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Sample records for stringent performance criteria

  1. The effect of increasingly stringent diagnostic criteria on sex ...

    African Journals Online (AJOL)

    Sex differences in premorbid function and symptomatology were examined as increasingly stringent criteria for schizophrenia were applied to 182 male and 139 female . psychotic patients. The male/female ratio rose from 1.6 among those meeting the CATEGO 'broad' criteria for schizophrenia to 3.7 among those satisfying ...

  2. Legal status and source of offenders' firearms in states with the least stringent criteria for gun ownership.

    Science.gov (United States)

    Vittes, Katherine A; Vernick, Jon S; Webster, Daniel W

    2013-02-01

    Gun possession by high-risk individuals presents a serious threat to public safety. U.S. federal law establishes minimum criteria for legal purchase and possession of firearms; many states have laws disqualifying additional categories for illegal possession. We used data from a national survey of state prison inmates to calculate: 1) the proportion of offenders, incarcerated for crimes committed with firearms in 13 states with the least restrictive firearm purchase and possession laws, who would have been prohibited if their states had stricter gun laws; and 2) the source of gun acquisition for offenders who were and were not legally permitted to purchase and possess firearms. Nearly three of ten gun offenders (73 of 253 or 28.9%) were legal gun possessors but would have been prohibited from purchasing or possessing firearms when committing their most recent offense if their states had stricter prohibitions. Offenders who were already prohibited under current law acquired their gun from a licensed dealer, where a background check is required, five times less often than offenders who were not prohibited (3.9% vs. 19.9%; χ(2)=13.31; p≤0.001). Nearly all (96.1%) offenders who were legally prohibited, acquired their gun from a supplier not required to conduct a background check. Stricter gun ownership laws would have made firearm possession illegal for many state prison inmates who used a gun to commit a crime. Requiring all gun sales to be subject to a background check would make it more difficult for these offenders to obtain guns.

  3. Criteria for performance evaluation

    Directory of Open Access Journals (Sweden)

    David J. Weiss

    2009-03-01

    Full Text Available Using a cognitive task (mental calculation and a perceptual-motor task (stylized golf putting, we examined differential proficiency using the CWS index and several other quantitative measures of performance. The CWS index (Weiss and Shanteau, 2003 is a coherence criterion that looks only at internal properties of the data without incorporating an external standard. In Experiment 1, college students (n = 20 carried out 2- and 3-digit addition and multiplication problems under time pressure. In Experiment 2, experienced golfers (n = 12, also college students, putted toward a target from nine different locations. Within each experiment, we analyzed the same responses using different methods. For the arithmetic tasks, accuracy information (mean absolute deviation from the correct answer, MAD using a coherence criterion was available; for golf, accuracy information using a correspondence criterion (mean deviation from the target, also MAD was available. We ranked the performances of the participants according to each measure, then compared the orders using Spearman's rextsubscript{s}. For mental calculation, the CWS order correlated moderately (rextsubscript{s} =.46 with that of MAD. However, a different coherence criterion, degree of model fit, did not correlate with either CWS or accuracy. For putting, the ranking generated by CWS correlated .68 with that generated by MAD. Consensual answers were also available for both experiments, and the rankings they generated correlated highly with those of MAD. The coherence vs. correspondence distinction did not map well onto criteria for performance evaluation.

  4. Are Dutch residents ready for a more stringent policy to enhance the energy performance of their homes?

    International Nuclear Information System (INIS)

    Middelkoop, Manon van; Vringer, Kees; Visser, Hans

    2017-01-01

    Investments in the energy performance of houses offer good prospects for reducing energy consumption and CO 2 emissions. However, people are not easily convinced of the need to take measures to improve the energy performance of their houses, even when financial benefits outweigh the costs. This article analyses the factors that influence the decision for improving the energy performance of existing homes, including policy instruments. Subsequently, the article provides policy suggestions on how to stimulate energy performance improvements. Both owners and tenants (50–70%) support government policy on energy performance improvements to existing homes. Nevertheless, people also have strong feelings of autonomy regarding their homes. Our results underline the importance of well-informed and competent decision-makers. Introducing the use of Energy Performance Certificates (EPCs) into the tax system for energy and residential buildings might therefore be an effective way to increase the interest of owners in the EPC, improve the use and effect of this informative instrument, and make the first step towards bridging the tension between autonomy and more stringent instruments.

  5. Impact of ANSI 2009 criteria for performance testing in TLD personnel monitoring

    International Nuclear Information System (INIS)

    MeenaI, P.; Rakesh, R.B.; Srivastava, Kshama; KoIambe, D.H.; Sapra, B.K.

    2014-01-01

    External Quality Assurance in TLD Personnel Monitoring Service was initiated in 1985, for periodic performance evaluation of various TLD Laboratories through postal exercise. Presently, all the 16 laboratories involved in Personnel Monitoring Service are covered under QA exercise. Since beginning, American National Standards Institute (ANSI) criteria have been adopted for performance testing in QA exercise. Presently, ANSI 2001 performance criteria along with ISO trumpet curve analysis method are being used for performance evaluation. In 2009, ANSI modified the performance evaluation criteria and this study evaluates its impact and feasibility of implementation of ANSI 2009 criteria in the quality assurance program for personnel monitoring. The performance of some laboratories evaluated using both ANSI 2001 and ANSI 2009 criteria have been discussed. The study shows that the ANSI 2009 criteria is more stringent and encourages even distribution of bias and standard deviation. This can be implemented with suitable modifications for performance evaluation

  6. Diagnostic criteria for sarcopenia and physical performance

    NARCIS (Netherlands)

    Bijlsma, A.Y.; Meskers, C.G.M.; van den Eshof, N.; Westendorp, R.G.; Sipila, S.; Stenroth, L.; Sillanpaa, E.; McPhee, J.S.; Jones, D.A.; Narici, M.V.; Gapeyeva, H.; Paasuke, M.; Voit, T.; Barnouin, Y.; Hogrel, J.Y.; Butler-Browne, G.; Maier, A.B.

    2014-01-01

    Relative and absolute muscle mass and muscle strength are used as diagnostic criteria for sarcopenia.We aimed to assess which diagnostic criteria are most associated with physical performance in 180 young (18-30 years) and 281 healthy old participants (69-81 years) of the European study MYOAGE.

  7. Education Criteria for Performance Excellence, 2002.

    Science.gov (United States)

    National Inst. of Standards and Technology, Gaithersburg, MD.

    The education criteria presented in this guide are designed to help organizations use an integrated approach to organizational performance management that results in delivery of ever-improving value to students and stakeholders. Implementation of the criteria will contribute to improvement of education quality, improvement of overall…

  8. Pulsed Inductive Plasma Acceleration: Performance Optimization Criteria

    Science.gov (United States)

    Polzin, Kurt A.

    2014-01-01

    Optimization criteria for pulsed inductive plasma acceleration are developed using an acceleration model consisting of a set of coupled circuit equations describing the time-varying current in the thruster and a one-dimensional momentum equation. The model is nondimensionalized, resulting in the identification of several scaling parameters that are varied to optimize the performance of the thruster. The analysis reveals the benefits of underdamped current waveforms and leads to a performance optimization criterion that requires the matching of the natural period of the discharge and the acceleration timescale imposed by the inertia of the working gas. In addition, the performance increases when a greater fraction of the propellant is initially located nearer to the inductive acceleration coil. While the dimensionless model uses a constant temperature formulation in calculating performance, the scaling parameters that yield the optimum performance are shown to be relatively invariant if a self-consistent description of energy in the plasma is instead used.

  9. Good Criteria for Supply Chain Performance Measurement

    Directory of Open Access Journals (Sweden)

    Elisa Kusrini

    2014-03-01

    conducted by distributing questionnaires to supply chain actors from different industry fields (both manufacturing and services in Indonesia using random sampling techniques. Data analysis using pairwise comparisons with an analytical Hierarchy Process model showed that efficient criteria were more important than effective criteria. Efficient criteria consisted of three sub-criteria: the amount of data is not too much and low cost and output is presented in a simple form. Effective criteria consisted of the criteria in the order of importance as follows: clarity, validity, comprehensiveness, responsiveness and dynamics. Further research is needed for developing a model that meets these criteria

  10. Models and criteria for waste repository performance

    International Nuclear Information System (INIS)

    Smith, C.F.; Cohen, J.J.

    1981-03-01

    A primary objective of the Waste Management Program is to assure that public health is protected. Predictive modeling, to some extent, will play a role in assuring that this objective is met. This paper considers the requirements and limitations of predictive modeling in providing useful inputs to waste management decision making. Criteria development needs and the relation between criteria and models are also discussed

  11. NWTS program criteria for mined geologic disposal of nuclear wasite: site performance criteria

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-02-01

    This report states ten criteria governing the suitability of sites for mined geologic disposal of high-level radioactive waste. The Department of Energy will use these criteria in its search for sites and will reevaluate their use when the Nuclear Regulatory Commission issues radioactive waste repository rules. These criteria encompass site geometry, geohydrology, geochemistry, geologic characteristics, tectonic environment, human intrusion, surface characteristics, environment, and potential socioeconomic impacts. The contents of this document include background discussion, site performance criteria, and appendices. The background section describes the waste disposal system, the application of the site criteria, and applicable criteria from NWTS-33(1) - Program Objectives, Functional Requirements and System Performance Criteria. Appendix A, entitled Comparison with Other Siting Criteria compares the NWTS criteria with those recommended by other agencies. Appendix B contains DOE responses to public comments received on the January 1980 draft of this document. Appendix C is a glossary.

  12. NWTS program criteria for mined geologic disposal of nuclear wasite: site performance criteria

    International Nuclear Information System (INIS)

    1981-02-01

    This report states ten criteria governing the suitability of sites for mined geologic disposal of high-level radioactive waste. The Department of Energy will use these criteria in its search for sites and will reevaluate their use when the Nuclear Regulatory Commission issues radioactive waste repository rules. These criteria encompass site geometry, geohydrology, geochemistry, geologic characteristics, tectonic environment, human intrusion, surface characteristics, environment, and potential socioeconomic impacts. The contents of this document include background discussion, site performance criteria, and appendices. The background section describes the waste disposal system, the application of the site criteria, and applicable criteria from NWTS-33(1) - Program Objectives, Functional Requirements and System Performance Criteria. Appendix A, entitled Comparison with Other Siting Criteria compares the NWTS criteria with those recommended by other agencies. Appendix B contains DOE responses to public comments received on the January 1980 draft of this document. Appendix C is a glossary

  13. Models and criteria for LLW disposal performance

    International Nuclear Information System (INIS)

    Smith, C.F.; Cohen, J.J.

    1980-12-01

    A primary objective of the Low Level Waste (LLW) Management Program is to assure that public health is protected. Predictive modeling, to some extent, will play a role in meeting this objective. This paper considers the requirements and limitations of predictive modeling in providing useful inputs to waste mangement decision making. In addition, criteria development needs and the relation between criteria and models are discussed

  14. Models and criteria for LLW disposal performance

    International Nuclear Information System (INIS)

    Smith, C.F.; Cohen, J.J.

    1980-01-01

    A primary objective of the Low Level Waste (LLW) Management Program is to assure that public health is protected. Predictive modeling, to some extent, will play a role in meeting this objective. This paper considers the requirements and limitations of predictive modeling in providing useful inputs to waste management decision making. In addition, criteria development needs and the relation between criteria and models are discussed

  15. The Impact on IPO Performance of More Stringent Listing Rules with a Pre-listing Earnings Requirement: Evidence from Hong Kong

    OpenAIRE

    Wai-yan Cheng; Yan-leung Cheung; Yuen-ching Tse

    2005-01-01

    This study considers the impact of a change to listing rules covering IPO performance in the Hong Kong stock market. The change, introduced in 1994, imposed a three-year pre-listing earning requirement on new issues. The objective of this research is to screen out a subset of poor IPO performers. We find there is no significant difference in performance between IPOs before and after the regulatory change. We further divide our sample of IPOs registered before the regulatory change into two su...

  16. Identifying the connective strength between model parameters and performance criteria

    Directory of Open Access Journals (Sweden)

    B. Guse

    2017-11-01

    Full Text Available In hydrological models, parameters are used to represent the time-invariant characteristics of catchments and to capture different aspects of hydrological response. Hence, model parameters need to be identified based on their role in controlling the hydrological behaviour. For the identification of meaningful parameter values, multiple and complementary performance criteria are used that compare modelled and measured discharge time series. The reliability of the identification of hydrologically meaningful model parameter values depends on how distinctly a model parameter can be assigned to one of the performance criteria. To investigate this, we introduce the new concept of connective strength between model parameters and performance criteria. The connective strength assesses the intensity in the interrelationship between model parameters and performance criteria in a bijective way. In our analysis of connective strength, model simulations are carried out based on a latin hypercube sampling. Ten performance criteria including Nash–Sutcliffe efficiency (NSE, Kling–Gupta efficiency (KGE and its three components (alpha, beta and r as well as RSR (the ratio of the root mean square error to the standard deviation for different segments of the flow duration curve (FDC are calculated. With a joint analysis of two regression tree (RT approaches, we derive how a model parameter is connected to different performance criteria. At first, RTs are constructed using each performance criterion as the target variable to detect the most relevant model parameters for each performance criterion. Secondly, RTs are constructed using each parameter as the target variable to detect which performance criteria are impacted by changes in the values of one distinct model parameter. Based on this, appropriate performance criteria are identified for each model parameter. In this study, a high bijective connective strength between model parameters and performance criteria

  17. State-wide performance criteria for international safeguards

    International Nuclear Information System (INIS)

    Budlong-Sylvester, K.W.; Pilat, Joseph F.; Stanbro, W.D.

    2001-01-01

    Traditionally, the International Atomic Energy Agency (IAEA) has relied upon prescriptive criteria to guide safeguards implementation. The prospect of replacing prescriptive safeguards criteria with more flexible performance criteria would constitute a structural change in safeguards and raises several important questions. Performance criteria imply that while safeguards goals will be fixed, the means of attaining those goals will not be explicitly prescribed. What would the performance objectives be under such a system? How would they be formulated? How would performance be linked to higher level safeguards objectives? How would safeguards performance be measured State-wide? The implementation of safeguards under performance criteria would also signal a dramatic change in the manner the Agency does business. A higher degree of flexibility could, in principle, produce greater effectiveness and efficiency, but would come with a need for increased Agency responsibility in practice. To the extent that reliance on prescriptive criteria decreases, the burden of justifying actions and ensuring their transparency will rise. Would there need to be limits to safeguards implementation? What would be the basis for setting such limits? This paper addresses these and other issues and questions relating to both the formulation and the implementation of performance-based criteria.

  18. Performance Criteria of Nuclear Space Propulsion Systems

    Science.gov (United States)

    Shepherd, L. R.

    Future exploration of the solar system on a major scale will require propulsion systems capable of performance far greater than is achievable with the present generation of rocket engines using chemical propellants. Viable missions going deeper into interstellar space will be even more demanding. Propulsion systems based on nuclear energy sources, fission or (eventually) fusion offer the best prospect for meeting the requirements. The most obvious gain coming from the application of nuclear reactions is the possibility, at least in principle, of obtaining specific impulses a thousandfold greater than can be achieved in chemically energised rockets. However, practical considerations preclude the possibility of exploiting the full potential of nuclear energy sources in any engines conceivable in terms of presently known technology. Achievable propulsive power is a particularly limiting factor, since this determines the acceleration that may be obtained. Conventional chemical rocket engines have specific propulsive powers (power per unit engine mass) in the order of gigawatts per tonne. One cannot envisage the possibility of approaching such a level of performance by orders of magnitude in presently conceivable nuclear propulsive systems. The time taken, under power, to reach a given terminal velocity is proportional to the square of the engine's exhaust velocity and the inverse of its specific power. An assessment of various nuclear propulsion concepts suggests that, even with the most optimistic assumptions, it could take many hundreds of years to attain the velocities necessary to reach the nearest stars. Exploration within a range of the order of a thousand AU, however, would appear to offer viable prospects, even with the low levels of specific power of presently conceivable nuclear engines.

  19. Comparison of urine iodine/creatinine ratio between patients following stringent and less stringent low iodine diet for radioiodine remnant ablation of thyroid cancer

    International Nuclear Information System (INIS)

    Roh, Jee Ho; Kim, Byung Il; Ha, Ji Su; Chang, Sei Joong; Shin, Hye Young; Choi, Joon Hyuk; Kim, Do Min; Kim, Chong Soon

    2006-01-01

    A low iodine diet (LID) for 1 ∼ 2 weeks is recommended for patients who undergoing radioiodine remnant ablation. However, the LID educations for patients are different among centers because there is no concrete recommendation for protocol of LID. In this investigation, we compared two representative types of LID protocols performed in several centers in Korea using urine iodine to creatinine tatio (urine I/Cr). From 2006, April to June, patients referred to our center for radioiodine remnant ablation of thyroid cancer from several local hospitals which had different LID protocols were included. We divided into two groups, stringent LID for 1 week and less stringent LID for 2 weeks, then measured their urine I/Cr ratio with spot urine when patients were admitted to the hospital. Total 27 patients were included in this investigation (M:F = 1:26; 13 in one-week stringent LID; 14 in two-week less stringent LID). Average of urine I/Cr ratio was 127.87 ± 78.52 μ g/g in stringent LID for 1 week, and 289.75 ± 188.24 μ g/g in less stringent LID for 2 weeks. It was significantly lower in stringent LID for 1 week group (ρ = 0.008). The number of patients whose urine I/Cr ratios were below 100 μ g/g was 6 of 13 in stringent LID for 1 week group, and 3 of 14 in less stringent LID for 2 weeks group. Stringent LID for 1 week resulted in better urinary I/Cr ratio in our investigation compared with the other protocol. However it still resulted in plenty of inadequate range of I/Cr ratio, so more stringent protocol such as stringent LID for 2 weeks is expected more desirable

  20. Interim performance criteria for photovoltaic energy systems. [Glossary included

    Energy Technology Data Exchange (ETDEWEB)

    DeBlasio, R.; Forman, S.; Hogan, S.; Nuss, G.; Post, H.; Ross, R.; Schafft, H.

    1980-12-01

    This document is a response to the Photovoltaic Research, Development, and Demonstration Act of 1978 (P.L. 95-590) which required the generation of performance criteria for photovoltaic energy systems. Since the document is evolutionary and will be updated, the term interim is used. More than 50 experts in the photovoltaic field have contributed in the writing and review of the 179 performance criteria listed in this document. The performance criteria address characteristics of present-day photovoltaic systems that are of interest to manufacturers, government agencies, purchasers, and all others interested in various aspects of photovoltaic system performance and safety. The performance criteria apply to the system as a whole and to its possible subsystems: array, power conditioning, monitor and control, storage, cabling, and power distribution. They are further categorized according to the following performance attributes: electrical, thermal, mechanical/structural, safety, durability/reliability, installation/operation/maintenance, and building/site. Each criterion contains a statement of expected performance (nonprescriptive), a method of evaluation, and a commentary with further information or justification. Over 50 references for background information are also given. A glossary with definitions relevant to photovoltaic systems and a section on test methods are presented in the appendices. Twenty test methods are included to measure performance characteristics of the subsystem elements. These test methods and other parts of the document will be expanded or revised as future experience and needs dictate.

  1. Operator performance evaluation using multi criteria decision making methods

    Science.gov (United States)

    Rani, Ruzanita Mat; Ismail, Wan Rosmanira; Razali, Siti Fatihah

    2014-06-01

    Operator performance evaluation is a very important operation in labor-intensive manufacturing industry because the company's productivity depends on the performance of its operators. The aims of operator performance evaluation are to give feedback to operators on their performance, to increase company's productivity and to identify strengths and weaknesses of each operator. In this paper, six multi criteria decision making methods; Analytical Hierarchy Process (AHP), fuzzy AHP (FAHP), ELECTRE, PROMETHEE II, Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) and VlseKriterijumska Optimizacija I Kompromisno Resenje (VIKOR) are used to evaluate the operators' performance and to rank the operators. The performance evaluation is based on six main criteria; competency, experience and skill, teamwork and time punctuality, personal characteristics, capability and outcome. The study was conducted at one of the SME food manufacturing companies in Selangor. From the study, it is found that AHP and FAHP yielded the "outcome" criteria as the most important criteria. The results of operator performance evaluation showed that the same operator is ranked the first using all six methods.

  2. Detection methods and performance criteria for genetically modified organisms.

    Science.gov (United States)

    Bertheau, Yves; Diolez, Annick; Kobilinsky, André; Magin, Kimberly

    2002-01-01

    Detection methods for genetically modified organisms (GMOs) are necessary for many applications, from seed purity assessment to compliance of food labeling in several countries. Numerous analytical methods are currently used or under development to support these needs. The currently used methods are bioassays and protein- and DNA-based detection protocols. To avoid discrepancy of results between such largely different methods and, for instance, the potential resulting legal actions, compatibility of the methods is urgently needed. Performance criteria of methods allow evaluation against a common standard. The more-common performance criteria for detection methods are precision, accuracy, sensitivity, and specificity, which together specifically address other terms used to describe the performance of a method, such as applicability, selectivity, calibration, trueness, precision, recovery, operating range, limit of quantitation, limit of detection, and ruggedness. Performance criteria should provide objective tools to accept or reject specific methods, to validate them, to ensure compatibility between validated methods, and be used on a routine basis to reject data outside an acceptable range of variability. When selecting a method of detection, it is also important to consider its applicability, its field of applications, and its limitations, by including factors such as its ability to detect the target analyte in a given matrix, the duration of the analyses, its cost effectiveness, and the necessary sample sizes for testing. Thus, the current GMO detection methods should be evaluated against a common set of performance criteria.

  3. Seismic design and evaluation criteria based on target performance goals

    International Nuclear Information System (INIS)

    Murray, R.C.; Nelson, T.A.; Kennedy, R.P.; Short, S.A.

    1994-04-01

    The Department of Energy utilizes deterministic seismic design/evaluation criteria developed to achieve probabilistic performance goals. These seismic design and evaluation criteria are intended to apply equally to the design of new facilities and to the evaluation of existing facilities. In addition, the criteria are intended to cover design and evaluation of buildings, equipment, piping, and other structures. Four separate sets of seismic design/evaluation criteria have been presented each with a different performance goal. In all these criteria, earthquake loading is selected from seismic hazard curves on a probabilistic basis but seismic response evaluation methods and acceptable behavior limits are deterministic approaches with which design engineers are familiar. For analytical evaluations, conservatism has been introduced through the use of conservative inelastic demand-capacity ratios combined with ductile detailing requirements, through the use of minimum specified material strengths and conservative code capacity equations, and through the use of a seismic scale factor. For evaluation by testing or by experience data, conservatism has been introduced through the use of an increase scale factor which is applied to the prescribed design/evaluation input motion

  4. Catalysis for biorefineries-performance criteria for industrial operation

    NARCIS (Netherlands)

    Lange, Jean Paul

    2016-01-01

    Past analyses of industrial processes for fuel and chemical manufacturing led to a few performance criteria that are critical for viable industrial operation. The present paper reviews these factors and provides a target window for each of them. It then illustrates their relevance for biorefineries

  5. Relating microbiological criteria to food safety objectives and performance objectives

    NARCIS (Netherlands)

    Schothorst, van M.; Zwietering, M.H.; Ross, T.; Buchanan, R.L.; Cole, M.B.

    2009-01-01

    Microbiological criteria, food safety objectives and performance objectives, and the relationship between them are discussed and described in the context of risk-based food safety management. A modified method to quantify the sensitivity of attributes sampling plans is presented to show how sampling

  6. Quality improvement using the Baldrige Criteria for Organizational Performance Excellence.

    Science.gov (United States)

    DeJong, Douglas J

    2009-06-01

    The criteria needed to achieve the Malcolm Baldrige National Quality Award (MBNQA) are described. The MBNQA was created in 1987 to recognize quality and performance and to encourage excellence in American companies. In 2003, Saint Luke's Hospital, the largest hospital in the Saint Luke's Health System, received the MBNQA. In the years since, the hospital has continued to use the Baldrige approach and has pursued the award on the health-system level. The Baldrige Criteria for Organizational Performance Excellence provide a framework that focuses on obtaining the highest levels of organizational excellence. These criteria consist of seven categories-leadership; strategic planning; focus on patients, customers, and markets; measurement, analysis, and knowledge management; work-force focus; process management; and results. At Saint Luke's Hospital, a category leader was designated for each of the seven categories in order to fully apply the criteria to the organization. Pharmacy leaders worked closely with each category leader to ensure that the appropriate format was being followed and to contribute positively to the written application and the site visit conducted by MBNQA examiners. The MBNQA involves its own vernacular and pattern. Effort should be made to fully understand and embrace the path that the organization's leaders have chosen. Departmental activities should be placed in front of an individual's leadership so that he or she can play an active part in demonstrating quality-improvement success stories. The criteria for the MBNQA are structured around seven categories that form a framework by which any organization or department can structure its own pursuit of quality and excellence. Pharmacy leaders can play an important role in the successful pursuit of quality within their organization.

  7. Automated cephalometry: system performance reliability using landmark-dependent criteria.

    Science.gov (United States)

    Tanikawa, Chihiro; Yagi, Masakazu; Takada, Kenji

    2009-11-01

    The purpose of the present study was to evaluate reliability of a system that performs automatic recognition of anatomic landmarks and adjacent structures on lateral cephalograms using landmark-dependent criteria unique to each landmark. To evaluate the reliability of the system, the system was used to examine 65 lateral cephalograms. The area of each system-identified anatomic structure surrounding the landmark and the position of each system-identified landmark were compared with norms using confidence ellipses with alpha = .01, which were derived from the scattergrams of 100 estimates obtained according to the method reported by Baumrind and Frantz. When the system-identified area overlapped with the norm area, anatomic structure recognition was considered successful. In addition, when the system-identified point was located within the norm area, landmark identification was considered successful. Based on these judgment criteria, success rates were calculated for all landmarks. The system successfully identified all specified anatomic structures in all the images and determined the positions of the landmarks with a mean success rate of 88% (range, 77%- 100%). With the incorporation of the rational assessment criteria provided by confidence ellipses, the proposed system was confirmed to be reliable.

  8. The strategic selecting criteria and performance by using the multiple criteria method

    Directory of Open Access Journals (Sweden)

    Lisa Y. Chen

    2008-02-01

    Full Text Available As the increasing competitive intensity in the current service market, organizational capabilities have been recognized as the importance of sustaining competitive advantage. The profitable growth for the firms has been fueled a need to systematically assess and renew the organization. The purpose of this study is to analyze the financial performance of the firms to create an effective evaluating structure for the Taiwan's service industry. This study utilized TOPSIS (technique for order preference by similarity to ideal solution method to evaluate the operating performance of 12 companies. TOPSIS is a multiple criteria decision making method to identify solutions from a finite set of alternatives based upon simultaneous minimization of distance from an ideal point and maximization of distance from a nadir point. By using this approach, this study measures the financial performance of firms through two aspects and ten indicators. The result indicated e-life had outstanding performance among the 12 retailers. The findings of this study provided managers to better understand their market position, competition, and profitability for future strategic planning and operational management.

  9. Correlating selection criteria with subsequent performance as residents.

    Science.gov (United States)

    Dirschl, Douglas R; Dahners, Laurence E; Adams, George L; Crouch, John H; Wilson, Frank C

    2002-06-01

    The objective of this study was to determine which criteria in the residency application had the highest correlation with subsequent performance of orthopaedic residents. Data collected from the application files of 58 residents included scores on standardized tests, number of honors grades in the basic and clinical years of medical school, election to Alpha Omega Alpha, numbers of research projects and publications, and numbers of extracurricular activities. Measures of performance included scores on the Orthopaedic In-Training Examination and American Board of Orthopaedic Surgery Part I Examination, and faculty evaluations of overall, cognitive, affective, and psychomotor performance. The number of honors grades on clinical rotations was the strongest predictor of performance, whereas election to Alpha Omega Alpha was second. The only other significant correlation was between the number of fine motor activities and psychomotor performance. None of the predictor variables had a significant correlation with Orthopaedic In-Training Examination or American Board of Orthopaedic Surgery Examination scores. Consistency between faculty rankings in each of the four categories was supported by regression analysis. From the results of this study, it appears that academic performance in clinical clerkships in medical school is the most predictive of resident performance. Range restriction in the data available for orthopaedic residency applicants, however, likely precludes the development of a reliable model to assist in the selection of orthopaedic residents.

  10. Performance Criteria for Capture and/or Immobilization Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Jubin, R. T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Bruffey, S. H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Strachan, D. M. [Strata-G, LLC, Knoxville, TN (United States); Soelberg, N. R. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Spencer, B. B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Riley, B. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-02-01

    The capture and subsequent immobilization of the four volatile radionuclides (3H, 14C, 85Kr, and 129I) from the off-gas streams of a used nuclear fuel reprocessing facility has been a topic of substantial research interest for the US DOE and international colleagues. Regulations set forth by the US EPA direct that some or all of these radionuclides (based upon fuel burnup, fuel type, cooling time, etc.) will require removal, to some extent, from the plant effluent streams prior to discharge to the environment. Upon removal, the radionuclide, as well as any associated sorbent, is destined for waste. Research of separation and capture methodologies has included a wide range of technologies including liquid caustic scrubbing systems, solid adsorbents, and cryogenic distillation. The studies of waste forms have been correspondingly diverse. In considering the technologies available for future development and implementation of both sorbents and waste forms, it will be necessary to use benchmarked measures of performance to objectively evaluate each sorbent system or waste form. This document is intended to provide initial guidance on the types of performance criteria for capture materials and waste forms intended for use in the recycling removal and disposal of UNF and, where possible, the minimum acceptable values for those criteria.

  11. NWTS program criteria for mined geologic disposal of nuclear waste: repository performance and development criteria. Public draft

    Energy Technology Data Exchange (ETDEWEB)

    None

    1982-07-01

    This document, DOE/NWTS-33(3) is one of a series of documents to establish the National Waste Terminal Storage (NWTS) program criteria for mined geologic disposal of high-level radioactive waste. For both repository performance and repository development it delineates the criteria for design performance, radiological safety, mining safety, long-term containment and isolation, operations, and decommissioning. The US Department of Energy will use these criteria to guide the development of repositories to assist in achieving performance and will reevaluate their use when the US Nuclear Regulatory Commission issues radioactive waste repository rules.

  12. NWTS program criteria for mined geologic disposal of nuclear waste: repository performance and development criteria. Public draft

    International Nuclear Information System (INIS)

    1982-07-01

    This document, DOE/NWTS-33(3) is one of a series of documents to establish the National Waste Terminal Storage (NWTS) program criteria for mined geologic disposal of high-level radioactive waste. For both repository performance and repository development it delineates the criteria for design performance, radiological safety, mining safety, long-term containment and isolation, operations, and decommissioning. The US Department of Energy will use these criteria to guide the development of repositories to assist in achieving performance and will reevaluate their use when the US Nuclear Regulatory Commission issues radioactive waste repository rules

  13. MHA admission criteria and program performance: do they predict career performance?

    Science.gov (United States)

    Porter, J; Galfano, V J

    1987-01-01

    The purpose of this study was to determine to what extent admission criteria predict graduate school and career performance. The study also analyzed which objective and subjective criteria served as the best predictors. MHA graduates of the University of Minnesota from 1974 to 1977 were surveyed to assess career performance. Student files served as the data base on admission criteria and program performance. Career performance was measured by four variables: total compensation, satisfaction, fiscal responsibility, and level of authority. High levels of MHA program performance were associated with women who had high undergraduate GPAs from highly selective undergraduate colleges, were undergraduate business majors, and participated in extracurricular activities. High levels of compensation were associated with relatively low undergraduate GPAs, high levels of participation in undergraduate extracurricular activities, and being single at admission to graduate school. Admission to MHA programs should be based upon both objective and subjective criteria. Emphasis should be placed upon the selection process for MHA students since admission criteria are shown to explain 30 percent of the variability in graduate program performance, and as much as 65 percent of the variance in level of position authority.

  14. Performance Criteria of Spatial Development Projects Based on Interregional Integration

    Directory of Open Access Journals (Sweden)

    Elena Viktorovna Kurushina

    2018-03-01

    Full Text Available The search of efficient ways for the development of regional socio-economic space is a relevant problem. The authors consider the models of spatial organization according to the Spatial Development Strategy of the Russian Federation until 2030. We conduct the comparative analysis of scenarios for the polarized and diversified spatial growth. Many investigations consider the concepts of polarized and endogenous growth. This study proposes a methodology to assess the development of macroregions and to increase the viability of interregional integration projects. To develop this methodology, we formulate scientific principles and indirect criteria of the project performance conforming to the theory of regional integration. In addition to the territorial community and complementarity of the development potentials, regional integration in the country should be based on the principles of security, networking, limited quantity and awareness of the potential project participants. Integration should ensure synergetic effects and take into account cultural and historical closeness, that manifests in the common mentality and existing economic relations among regions. The calculation results regarding the indirect criteria are obtained using the methods of classification and spatial correlation. This study confirms the hypothesis, that the formation of the Western Siberian and Ural macro-regions is appropriate. We have concluded this on the basis of the criteria of economic development, economic integration, the similarity of regional spaces as habitats, and a number of participants for the subjects of the Ural Federal District. The projection of the patterns of international economic integration to the interregional level allows predicting the highest probability for the successful cooperation among the Western Siberian regions with a high level of economic development. The authors’ method has revealed a high synchronization between the economies of

  15. The effects of performance-based assessment criteria on student performance and self-assessment skills

    NARCIS (Netherlands)

    Fastré, Greet; Van der Klink, Marcel; Van Merriënboer, Jeroen

    2010-01-01

    Fastré, G. M. J., Van der Klink, M. R., & Van Merriënboer, J. J. G. (2010). The effects of performance-based assessment criteria on student performance and self-assessment skills. Advances in Health Science Education, 15(4), 517-532.

  16. Labs21 environmental performance criteria Version 2.0

    Energy Technology Data Exchange (ETDEWEB)

    Mathew, Paul A.

    2002-10-01

    Laboratory facilities present a unique challenge for energy efficient and sustainable design, with their inherent complexity of systems, health and safety requirements, long-term flexibility and adaptability needs, energy use intensity, and environmental impacts. The typical laboratory is about five times as energy intensive as a typical office building and costs about three times as much per unit area. The Labs21 Environmental Performance Criteria (EPC) is a rating system for use by laboratory building project stakeholders to assess the environmental performance of laboratory facilities. Currently, the U.S. Green Building Council's LEED{trademark} Rating System is the primary tool used. However, LEED{trademark} was designed for U.S. commercial office buildings and as such, lacks some attributes essential to the sustainable design of this unique and complex building type. To facilitate widespread use and to avoid ''re-inventing the wheel'' this effort builds on the existing LEED{trademark} Rating System 2.0.

  17. 78 FR 38735 - Autopsy Performance Criteria: Standards, Guidelines and Best Practices

    Science.gov (United States)

    2013-06-27

    ... DEPARTMENT OF JUSTICE Office of Justice Programs [OJP (NIJ) Docket No. 1626] Autopsy Performance Criteria: Standards, Guidelines and Best Practices AGENCY: National Institute of Justice, DOJ. ACTION... entitled, ``Autopsy Performance Criteria: Standards, Guidelines and Best Practices''. The opportunity to...

  18. Distortion product otoacoustic emission test performance for a priori criteria and for multifrequency audiometric standards.

    Science.gov (United States)

    Gorga, M P; Neely, S T; Dorn, P A

    1999-08-01

    1) To describe distortion product otoacoustic emission (DPOAE) test performance when a priori response criteria are applied to a large set of DPOAE data. 2) To describe DPOAE test performance when multifrequency definitions of auditory function are used. 3) To determine DPOAE test performance when a single decision regarding auditory status is made for an ear, based on DPOAE data from several frequencies. 4) To compare univariate and multivariate test performance when multifrequency gold standard definitions and response criteria are applied to DPOAE data. DPOAE and audiometric data were analyzed from 1267 ears of 806 subjects. These data were evaluated for three different frequency combinations (2, 3, 4 kHz; 2, 3, 4, 6 kHz; 1.5, 2, 3, 4, 6 kHz). DPOAE data were collected for each of the f2 frequencies listed above, using primary levels (L1/L2) of 65/55 dB SPL and a primary ratio (f2/f1) of 1.22. Sensitivity and specificity were evaluated for signal to noise ratios (SNRs) of 3, 6, and 9 dB, which are in common clinical use. In addition, test performance was evaluated using clinical decision theory, following the convention we have used in previous reports on otoacoustic emission test performance. Both univariate and multivariate analyses techniques were applied to the data. In addition to evaluating DPOAE test performance for the case when audiometric and f2 frequency were equal, multifrequency gold standards and multifrequency criterion responses were evaluated. Three new gold standards were used to assess test performance: average pure-tone thresholds, extrema thresholds that took into account both the magnitude of the loss and the number of frequencies at which hearing loss existed, and a combination of the two. These new gold standards were applied to each of the three frequency groups described above. As expected, SNR criteria of 3, 6, and 9 dB never resulted in perfect DPOAE test performance. Even the most stringent of these criteria (9 dB SNR) did not result

  19. Performance objectives and criteria for conducting DOE environmental audits

    International Nuclear Information System (INIS)

    1994-01-01

    This document contains the Performance Objectives and Criteria (POC) that have been developed for environmental audits and assessments conducted by the Office of the Assistant Secretary for Environment, Safety and Health. The Environmental POC can serve multiple purposes. Primarily, they are to serve as guidelines for the technical specialists conducted the audits and assessments, and for the team management. The POC can also serve as supporting documents for training of technical discipline specialists and Team Leaders and as bases for DOE programs and field offices and contractors conducting audit or assessment activities or improving environmental protection programs. It must be recognized that not all of the POC will necessarily apply to all DOE facilities. The users of this document must rely upon their knowledge of the facility and their professional judgment, or the judgment of qualified environmental professionals to determine the applicability of each POC. The POC cover eleven technical disciplines: air; surface water and drinking water quality; groundwater; waste management; toxic and chemical materials; radiation; quality assurance; inactive waste sites and releases; ecological and cultural resources; the National Environmental Policy Act (NEPA); and environmental management systems

  20. Performance objectives and criteria for conducting DOE environmental audits

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-01-01

    This document contains the Performance Objectives and Criteria (POC) that have been developed for environmental audits and assessments conducted by the Office of the Assistant Secretary for Environment, Safety and Health. The Environmental POC can serve multiple purposes. Primarily, they are to serve as guidelines for the technical specialists conducted the audits and assessments, and for the team management. The POC can also serve as supporting documents for training of technical discipline specialists and Team Leaders and as bases for DOE programs and field offices and contractors conducting audit or assessment activities or improving environmental protection programs. It must be recognized that not all of the POC will necessarily apply to all DOE facilities. The users of this document must rely upon their knowledge of the facility and their professional judgment, or the judgment of qualified environmental professionals to determine the applicability of each POC. The POC cover eleven technical disciplines: air; surface water and drinking water quality; groundwater; waste management; toxic and chemical materials; radiation; quality assurance; inactive waste sites and releases; ecological and cultural resources; the National Environmental Policy Act (NEPA); and environmental management systems.

  1. Dynamic Performance Characteristic Tests of Real Scale Lead Rubber Bearing for the Evaluation of Performance Criteria

    International Nuclear Information System (INIS)

    Kim, Min Kyu; Kim, Jung-Han; Choi, In-Kil

    2014-01-01

    Dynamic characteristic tests of full scale lead rubber bearing were performed for the evaluation of performance criteria of isolation system for nuclear power plants. For the dynamic test for a full scale rubber bearing, two 1500mm diameter lead rubber bearings were manufactured. The viewpoints of this dynamic test are determination of an ultimate shear strain level of lead rubber bearing, behavior of rubber bearing according to static and dynamic input motion, sinusoidal and random (earthquake) motion, and 1-dimentional and 2-dimensional input motion. In this study, seismic isolation device tests were performed for the evaluation of performance criteria of isolation system. Through this test, it can be recognized that in the case of considering a mechanical property test, dynamic and multi degree of loading conditions should be determined. But these differences should be examined how much affect to the global structural behavior

  2. Bulk development and stringent selection of microsatellite markers in the western flower thrips Frankliniella occidentalis.

    Science.gov (United States)

    Cao, Li-Jun; Li, Ze-Min; Wang, Ze-Hua; Zhu, Liang; Gong, Ya-Jun; Chen, Min; Wei, Shu-Jun

    2016-05-20

    Recent improvements in next-generation sequencing technologies have enabled investigation of microsatellites on a genome-wide scale. Faced with a huge amount of candidates, the use of appropriate marker selection criteria is crucial. Here, we used the western flower thrips Frankliniella occidentalis for an empirical microsatellite survey and validation; 132,251 candidate microsatellites were identified, 92,102 of which were perfect. Dinucleotides were the most abundant category, while (AG)n was the most abundant motif. Sixty primer pairs were designed and validated in two natural populations, of which 30 loci were polymorphic, stable, and repeatable, but not all in Hardy-Weinberg equilibrium (HWE) and linkage equilibrium. Four marker panels were constructed to understand effect of marker selection on population genetic analyses: (i) only accept loci with single nucleotide insertions (SNI); (ii) only accept the most polymorphic loci (MP); (iii) only accept loci that did not deviate from HWE, did not show SNIs, and had unambiguous peaks (SS) and (iv) all developed markers (ALL). Although the MP panel resulted in microsatellites of highest genetic diversity followed by the SNI, the SS performed best in individual assignment. Our study proposes stringent criteria for selection of microsatellites from a large-scale number of genomic candidates for population genetic studies.

  3. Flight Hardware Packaging Design for Stringent EMC Radiated Emission Requirements

    Science.gov (United States)

    Lortz, Charlene L.; Huang, Chi-Chien N.; Ravich, Joshua A.; Steiner, Carl N.

    2013-01-01

    This packaging design approach can help heritage hardware meet a flight project's stringent EMC radiated emissions requirement. The approach requires only minor modifications to a hardware's chassis and mainly concentrates on its connector interfaces. The solution is to raise the surface area where the connector is mounted by a few millimeters using a pedestal, and then wrapping with conductive tape from the cable backshell down to the surface-mounted connector. This design approach has been applied to JPL flight project subsystems. The EMC radiated emissions requirements for flight projects can vary from benign to mission critical. If the project's EMC requirements are stringent, the best approach to meet EMC requirements would be to design an EMC control program for the project early on and implement EMC design techniques starting with the circuit board layout. This is the ideal scenario for hardware that is built from scratch. Implementation of EMC radiated emissions mitigation techniques can mature as the design progresses, with minimal impact to the design cycle. The real challenge exists for hardware that is planned to be flown following a built-to-print approach, in which heritage hardware from a past project with a different set of requirements is expected to perform satisfactorily for a new project. With acceptance of heritage, the design would already be established (circuit board layout and components have already been pre-determined), and hence any radiated emissions mitigation techniques would only be applicable at the packaging level. The key is to take a heritage design with its known radiated emissions spectrum and repackage, or modify its chassis design so that it would have a better chance of meeting the new project s radiated emissions requirements.

  4. On the choice of performance assessment criteria and their impact on the overall system performance

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik; Green, Torben

    2010-01-01

    The aim of this paper is to illuminate the impact of the choice of a system’s performance criteria on the quality of the corresponding monitoring system’s assessment results. Special attention is given to the performance issues that are caused by or can be solved by control actions. The compressor...... capacity gap issue in the supermarket refrigeration systems is used as a case study to elaborate on the problem through employment of both real life field data as well as simulation data. A performance function that can capture the compressor capacity gap problem is presented in the paper and used...... to evaluate both data from the real supermarket system and the data generated by the simulation model....

  5. Are regulation-driven performance criteria still acceptable? - The German point of view.

    Science.gov (United States)

    Orth, Matthias

    2015-05-01

    Performance criteria should be a challenge for the laboratories to improve their quality. In countries with mandatory proficiency testing, the definition of performance criteria is a particular issue. If the definition of performance criteria is mandated from the regulatory bodies to medico-scientific institutions, scientific approaches (i.e., based on biological variation), the state-of-the-art approach (i.e., based on technical feasibility) as well as medical needs can be used to set up performance criteria such as the Richtlinie der Bundesärztekammer (RiliBÄK; Guideline of the German Medical Association on Quality Assurance in Medical Laboratory Examinations) in Germany. The experiences with RiliBÄK show that these performance criteria have to be revised on an ongoing basis.

  6. The performance profile: A multi–criteria performance evaluation method for test–based problems

    Directory of Open Access Journals (Sweden)

    Jaśkowski Wojciech

    2016-03-01

    Full Text Available In test-based problems, solutions produced by search algorithms are typically assessed using average outcomes of interactions with multiple tests. This aggregation leads to information loss, which can render different solutions apparently indifferent and hinder comparison of search algorithms. In this paper we introduce the performance profile, a generic, domain-independent, multi-criteria performance evaluation method that mitigates this problem by characterizing the performance of a solution by a vector of outcomes of interactions with tests of various difficulty. To demonstrate the usefulness of this gauge, we employ it to analyze the behavior of Othello and Iterated Prisoner’s Dilemma players produced by five (coevolutionary algorithms as well as players known from previous publications. Performance profiles reveal interesting differences between the players, which escape the attention of the scalar performance measure of the expected utility. In particular, they allow us to observe that evolution with random sampling produces players coping well against the mediocre opponents, while the coevolutionary and temporal difference learning strategies play better against the high-grade opponents. We postulate that performance profiles improve our understanding of characteristics of search algorithms applied to arbitrary test-based problems, and can prospectively help design better methods for interactive domains.

  7. Private and social costs of surface mine reforestation performance criteria.

    Science.gov (United States)

    Sullivan, Jay; Amacher, Gregory S

    2010-02-01

    We study the potentially unnecessary costs imposed by strict performance standards for forest restoration of surface coal mines in the Appalachian region under the Surface Mining Control and Reclamation Act of 1977 (SMCRA) that can vary widely across states. Both the unnecessary private costs to the mine operator and costs to society (social costs) are reported for two performance standards, a ground cover requirement, and a seedling survival target. These standards are examined using numerical analyses under a range of site productivity class and market conditions. We show that a strict (90%) ground cover standard may produce an unnecessary private cost of more than $700/ha and a social cost ranging from $428/ha to $710/ha, as compared with a 70% standard. A strict tree survival standard of 1235 trees/ha, as compared with the more typical 1087 trees/ha standard, may produce an unnecessary private cost of approximately $200/ha, and a social cost in the range of $120 to $208/ha. We conclude that strict performance standards may impose substantial unnecessary private costs and social costs, that strict performance standards may be discouraging the choice of forestry as a post-mining land use, and that opportunities exist for reform of reforestation performance standards. Our study provides a basis for evaluating tradeoffs between regulatory efficiency and optimal reforestation effort.

  8. Establishing Pass/Fail Criteria for Bronchoscopy Performance

    DEFF Research Database (Denmark)

    Konge, Lars; Clementsen, Paul; Larsen, Klaus Richter

    2012-01-01

    Background: Several tools have been created to assess competence in bronchoscopy. However, educational guidelines still use an arbitrary number of performed procedures to decide when basic competency is acquired. Objectives: The purpose of this study was to define pass/fail scores for two...... method. In the first we compared bronchoscopy performance scores of 14 novices with the scores of 14 experienced consultants to find the score that best discriminated between the two groups. In the second we asked an expert group of 7 experienced bronchoscopists to judge how a borderline trainee would...

  9. Performance criteria for structural concrete | Dinku | Zede Journal

    African Journals Online (AJOL)

    In this paper, the durability of concrete in general and the gaf permeability of concrete in pariicular are theoretically explained and some durability test results obtained from laboratory investigation are discussed. A simple and practical gaf permeability meafurement apparatus. which enables to assess the performance ...

  10. Performance Based Criteria for Ship Collision and Grounding

    DEFF Research Database (Denmark)

    Pedersen, Preben Terndrup

    2009-01-01

    The paper outlines a probabilistic procedure whereby the maritime industry can develop performance based rules to reduce the risk associated with human, environmental and economic costs of collision and grounding events and identify the most economic risk control options associated with prevention...

  11. Performance criteria for reference measurement procedures and reference materials.

    Science.gov (United States)

    Schimmel, Heinz; Zegers, Ingrid

    2015-05-01

    The concept of metrological traceability of measurement results to property values assigned to measurement standards of higher metrological order or to the International System of Units (SI) through sequential calibrations, using reference materials and reference measurement procedures, plays a key role in ensuring that end user measurement procedures perform at an acceptable level in the clinical context. The aim is that measurement results produced over time or by different end users or with different end user measurement procedures for the same measurand will be equivalent within their corresponding uncertainties. These goals can only be reached under certain conditions and if requirements laid down in international standards on calibration concepts, reference measurement procedures and reference materials are fulfilled. Calibration hierarchies have to be implemented correctly and parameters contributing to measurement uncertainty and systematic bias need to be controlled and eliminated, respectively, by technically improving methods and reference materials and intermediate calibrators used for effectively achieving equivalence of measurement results and for meeting analytical performance requirements for in vitro diagnostic devices.

  12. Performance criteria for solidified high-level radioactive wastes. Environmental impact statement. Revision 1

    International Nuclear Information System (INIS)

    1977-09-01

    This draft Environmental Impact Statement on performance criteria for solidified high-level radioactive wastes (PCSHLW) covers: considerations for PCSHLW development, the proposed rulemaking, characteristics of the PCSHLW, environmental impacts of the proposed PCSHLW, alternatives to the PCSHLW criteria, and cost/benefit/risk evaluation. Five appendices are included to support the technical data required in the Environmental Impact Statement

  13. 40 CFR 262.104 - What are the minimum performance criteria?

    Science.gov (United States)

    2010-07-01

    ...) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE University Laboratories... criteria? The Minimum Performance Criteria that each University must meet in managing its Laboratory Waste are: (a) Each University must label all laboratory waste with the general hazard class and either the...

  14. Circuitry linking the Csr and stringent response global regulatory systems.

    Science.gov (United States)

    Edwards, Adrianne N; Patterson-Fortin, Laura M; Vakulskas, Christopher A; Mercante, Jeffrey W; Potrykus, Katarzyna; Vinella, Daniel; Camacho, Martha I; Fields, Joshua A; Thompson, Stuart A; Georgellis, Dimitris; Cashel, Michael; Babitzke, Paul; Romeo, Tony

    2011-06-01

    CsrA protein regulates important cellular processes by binding to target mRNAs and altering their translation and/or stability. In Escherichia coli, CsrA binds to sRNAs, CsrB and CsrC, which sequester CsrA and antagonize its activity. Here, mRNAs for relA, spoT and dksA of the stringent response system were found among 721 different transcripts that copurified with CsrA. Many of the transcripts that copurified with CsrA were previously determined to respond to ppGpp and/or DksA. We examined multiple regulatory interactions between the Csr and stringent response systems. Most importantly, DksA and ppGpp robustly activated csrB/C transcription (10-fold), while they modestly activated csrA expression. We propose that CsrA-mediated regulation is relieved during the stringent response. Gel shift assays confirmed high affinity binding of CsrA to relA mRNA leader and weaker interactions with dksA and spoT. Reporter fusions, qRT-PCR and immunoblotting showed that CsrA repressed relA expression, and (p)ppGpp accumulation during stringent response was enhanced in a csrA mutant. CsrA had modest to negligible effects on dksA and spoT expression. Transcription of dksA was negatively autoregulated via a feedback loop that tended to mask CsrA effects. We propose that the Csr system fine-tunes the stringent response and discuss biological implications of the composite circuitry. © Published 2011. This article is a US Government work and is in the public domain in the USA.

  15. Admissions Criteria and Academic Performance in the AFIT Graduate Cost Analysis Program

    National Research Council Canada - National Science Library

    Garwood, Kenneth

    2002-01-01

    .... Using the cumulative graduate grade point average earned at AFIT as the measure of academic performance, comparisons were made between the predictive capability of the current criteria and other potential factors...

  16. 77 FR 19391 - Notice of Proposed Intelligent Mail Indicia Performance Criteria With Request for Comments

    Science.gov (United States)

    2012-03-30

    ... replacement of the current Information-Based Indicia Performance Criteria (IBI PC) with new Intelligent Mail.... Provides the minimum required information, both human- and machine-readable, for all pre-paid evidence of...

  17. Final waste forms project: Performance criteria for phase I treatability studies

    International Nuclear Information System (INIS)

    Gilliam, T.M.; Hutchins, D.A.; Chodak, P. III

    1994-06-01

    This document defines the product performance criteria to be used in Phase I of the Final Waste Forms Project. In Phase I, treatability studies will be performed to provide open-quotes proof-of-principleclose quotes data to establish the viability of stabilization/solidification (S/S) technologies. This information is required by March 1995. In Phase II, further treatability studies, some at the pilot scale, will be performed to provide sufficient data to allow treatment alternatives identified in Phase I to be more fully developed and evaluated, as well as to reduce performance uncertainties for those methods chosen to treat a specific waste. Three main factors influence the development and selection of an optimum waste form formulation and hence affect selection of performance criteria. These factors are regulatory, process-specific, and site-specific waste form standards or requirements. Clearly, the optimum waste form formulation will require consideration of performance criteria constraints from each of the three categories. Phase I will focus only on the regulatory criteria. These criteria may be considered the minimum criteria for an acceptable waste form. In other words, a S/S technology is considered viable only if it meet applicable regulatory criteria. The criteria to be utilized in the Phase I treatability studies were primarily taken from Environmental Protection Agency regulations addressed in 40 CFR 260 through 265 and 268; and Nuclear Regulatory Commission regulations addressed in 10 CFR 61. Thus the majority of the identified criteria are independent of waste form matrix composition (i.e., applicable to cement, glass, organic binders etc.)

  18. Final waste forms project: Performance criteria for phase I treatability studies

    Energy Technology Data Exchange (ETDEWEB)

    Gilliam, T.M. [Oak Ridge National Lab., TN (United States); Hutchins, D.A. [Martin Marietta Energy Systems, Inc., Oak Ridge, TN (United States); Chodak, P. III [Massachusetts Institute of Technology (United States)

    1994-06-01

    This document defines the product performance criteria to be used in Phase I of the Final Waste Forms Project. In Phase I, treatability studies will be performed to provide {open_quotes}proof-of-principle{close_quotes} data to establish the viability of stabilization/solidification (S/S) technologies. This information is required by March 1995. In Phase II, further treatability studies, some at the pilot scale, will be performed to provide sufficient data to allow treatment alternatives identified in Phase I to be more fully developed and evaluated, as well as to reduce performance uncertainties for those methods chosen to treat a specific waste. Three main factors influence the development and selection of an optimum waste form formulation and hence affect selection of performance criteria. These factors are regulatory, process-specific, and site-specific waste form standards or requirements. Clearly, the optimum waste form formulation will require consideration of performance criteria constraints from each of the three categories. Phase I will focus only on the regulatory criteria. These criteria may be considered the minimum criteria for an acceptable waste form. In other words, a S/S technology is considered viable only if it meet applicable regulatory criteria. The criteria to be utilized in the Phase I treatability studies were primarily taken from Environmental Protection Agency regulations addressed in 40 CFR 260 through 265 and 268; and Nuclear Regulatory Commission regulations addressed in 10 CFR 61. Thus the majority of the identified criteria are independent of waste form matrix composition (i.e., applicable to cement, glass, organic binders etc.).

  19. Evaluation criteria for enhanced solar–coal hybrid power plant performance

    International Nuclear Information System (INIS)

    Zhao, Yawen; Hong, Hui; Jin, Hongguang

    2014-01-01

    Attention has been directed toward hybridizing solar energy with fossil power plants since the 1990s to improve reliability and efficiency. Appropriate evaluation criteria were important in the design and optimization of solar–fossil hybrid systems. Two new criteria to evaluate the improved thermodynamic performances in a solar hybrid power plant were developed in this study. Correlations determined the main factors influencing the improved thermodynamic performances. The proposed criteria can be used to effectively integrate solar–coal hybridization systems. Typical 100 MW–1000 MW coal-fired power plants hybridized with solar heat at approximately 300 °C, which was used to preheat the feed water before entering the boiler, were evaluated using the criteria. The integration principle of solar–coal hybrid systems was also determined. The proposed evaluation criteria may be simple and reasonable for solar–coal hybrid systems with multi-energy input, thus directing system performance enhancement. - Highlights: • New criteria to evaluate the solar hybrid power plant were developed. • Typical solar–coal hybrid power plants were evaluated using the criteria. • The integration principle of solar–coal hybrid systems was determined. • The benefits of the solar–coal hybrid system are enhanced at lower solar radiation

  20. Evaluation of Flagging Criteria of United States Kidney Transplant Center Performance: How to Best Define Outliers?

    Science.gov (United States)

    Schold, Jesse D; Miller, Charles M; Henry, Mitchell L; Buccini, Laura D; Flechner, Stuart M; Goldfarb, David A; Poggio, Emilio D; Andreoni, Kenneth A

    2017-06-01

    Scientific Registry of Transplant Recipients report cards of US organ transplant center performance are publicly available and used for quality oversight. Low center performance (LP) evaluations are associated with changes in practice including reduced transplant rates and increased waitlist removals. In 2014, Scientific Registry of Transplant Recipients implemented new Bayesian methodology to evaluate performance which was not adopted by Center for Medicare and Medicaid Services (CMS). In May 2016, CMS altered their performance criteria, reducing the likelihood of LP evaluations. Our aims were to evaluate incidence, survival rates, and volume of LP centers with Bayesian, historical (old-CMS) and new-CMS criteria using 6 consecutive program-specific reports (PSR), January 2013 to July 2015 among adult kidney transplant centers. Bayesian, old-CMS and new-CMS criteria identified 13.4%, 8.3%, and 6.1% LP PSRs, respectively. Over the 3-year period, 31.9% (Bayesian), 23.4% (old-CMS), and 19.8% (new-CMS) of centers had 1 or more LP evaluation. For small centers (evaluations (52 vs 13 PSRs) for 1-year mortality with Bayesian versus new-CMS criteria. For large centers (>183 transplants/PSR), there were 3-fold additional LP evaluations for 1-year mortality with Bayesian versus new-CMS criteria with median differences in observed and expected patient survival of -1.6% and -2.2%, respectively. A significant proportion of kidney transplant centers are identified as low performing with relatively small survival differences compared with expected. Bayesian criteria have significantly higher flagging rates and new-CMS criteria modestly reduce flagging. Critical appraisal of performance criteria is needed to assess whether quality oversight is meeting intended goals and whether further modifications could reduce risk aversion, more efficiently allocate resources, and increase transplant opportunities.

  1. Is ionizing radiation regulated more stringently than chemical carcinogens

    International Nuclear Information System (INIS)

    Travis, C.C.; Pack, S.R.; Hattemer-Frey, H.A.

    1989-01-01

    It is widely believed that United States government agencies regulate exposure to ionizing radiation more stringently than exposure to chemical carcinogens. It is difficult to verify this perception, however, because chemical carcinogens and ionizing radiation are regulated using vastly different strategies. Chemical carcinogens are generally regulated individually. Regulators consider the risk of exposure to one chemical rather than the cumulative radiation exposure from all sources. Moreover, standards for chemical carcinogens are generally set in terms of quantities released or resultant environmental concentrations, while standards for ionizing radiation are set in terms of dose to the human body. Since chemicals and ionizing radiation cannot be compared on the basis of equal dose to the exposed individual, standards regulating chemicals and ionizing radiation cannot be compared directly. It is feasible, however, to compare the two sets of standards on the basis of equal risk to the exposed individual, assuming that standards for chemicals and ionizing radiation are equivalent if estimated risk levels are equitable. This paper compares risk levels associated with current standards for ionizing radiation and chemical carcinogens. The authors do not attempt to determine whether either type of risk is regulated too stringently or not stringently enough but endeavor only to ascertain if ionizing radiation is actually regulated more strictly than chemical carcinogens

  2. A study on the establishment of component/equipment performance criteria considering Heavy Water Reactor characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Keun Sun; Kwon, Young Chul; Lee, Min Kyu; Lee, Yun Soo [Sunmoon Univ., Asan (Korea, Republic of); Chang, Seong Hoong; Ryo, Chang Hyun [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Kim, Soong Pyung; Hwnag, Jung Rye; Chung, Chul Kee [Chosun Univ., Gwangju (Korea, Republic of)

    2002-03-15

    Foreign and domestic technology trends, regulatory requirements, design and researches for heavy water reactors are analyzed. Safety design guides of Canada industry and regulatory documents and consultative documents of Canada regulatory agency are reviewed. Applicability of MOST guidance 16 Revision 'guidance for technical criteria of nuclear reactor facility' is reviewed. Specific performance criteria are established for components and facilities for heavy water reactor.

  3. Lean Information Management: Criteria For Selecting Key Performance Indicators At Shop Floor

    Science.gov (United States)

    Iuga, Maria Virginia; Kifor, Claudiu Vasile; Rosca, Liviu-Ion

    2015-07-01

    Most successful organizations worldwide use key performance indicators as an important part of their corporate strategy in order to forecast, measure and plan their businesses. Performance metrics vary in their purpose, definition and content. Therefore, the way organizations select what they think are the optimal indicators for their businesses varies from company to company, sometimes even from department to department. This study aims to answer the question of what is the most suitable way to define and select key performance indicators. More than that, it identifies the right criteria to select key performance indicators at shop floor level. This paper contributes to prior research by analysing and comparing previously researched selection criteria and proposes an original six-criteria-model, which caters towards choosing the most adequate KPIs. Furthermore, the authors take the research a step further by further steps to closed research gaps within this field of study.

  4. Comparison of approaches to weighting of multiple criteria for selecting equipment to optimize performance and safety.

    Science.gov (United States)

    Agarski, Boris; Hadzistevic, Miodrag; Budak, Igor; Moraca, Slobodan; Vukelic, Djordje

    2017-12-08

    Nowadays every piece of working equipment and tools has to comply with safety standards and laws. This study investigated multi-criteria methods for selecting working equipment in order to optimize performance and occupational safety. The multi-criteria decision-making (MDCM) method was applied to the problem of selecting optimal working equipment using four different criterion weighting approaches (direct weighting, revised Simos procedure, Fuller's triangle and analytic hierarchy process). Groups of economic, technical and safety criteria were defined and five weighting scenarios were developed. Although the four weighting methods produced similar results, in some situations they produced different criterion weighting factors. The final output of the MCDM method was the identification of the optimal forklift in the five weighting scenarios. Although we have applied the MCDM method to a forklift selection problem, it can be applied to all sorts of working equipment in contexts where economic, technical and safety selection criteria can be identified.

  5. NWTS program criteria for mined geologic disposal of nuclear waste: program objectives, functional requirements, and system performance criteria

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-04-01

    At the present time, final repository criteria have not been issued by the responsible agencies. This document describes general objectives, requirements, and criteria that the DOE intends to apply in the interim to the National Waste Terminal Storage (NWTS) Program. These objectives, requirements, and criteria have been developed on the basis of DOE's analysis of what is needed to achieve the National objective of safe waste disposal in an environmentally acceptable and economic manner and are expected to be consistent with anticipated regulatory standards. The qualitative statements in this document address the broad issues of public and occupational health and safety, institutional acceptability, engineering feasibility, and economic considerations. A comprehensive set of criteria, general and project specific, of which these are a part, will constitute a portion of the technical basis for preparation and submittal by the DOE of formal documents to support future license applications for nuclear waste repositories.

  6. NWTS program criteria for mined geologic disposal of nuclear waste: program objectives, functional requirements, and system performance criteria

    International Nuclear Information System (INIS)

    1981-04-01

    At the present time, final repository criteria have not been issued by the responsible agencies. This document describes general objectives, requirements, and criteria that the DOE intends to apply in the interim to the National Waste Terminal Storage (NWTS) Program. These objectives, requirements, and criteria have been developed on the basis of DOE's analysis of what is needed to achieve the National objective of safe waste disposal in an environmentally acceptable and economic manner and are expected to be consistent with anticipated regulatory standards. The qualitative statements in this document address the broad issues of public and occupational health and safety, institutional acceptability, engineering feasibility, and economic considerations. A comprehensive set of criteria, general and project specific, of which these are a part, will constitute a portion of the technical basis for preparation and submittal by the DOE of formal documents to support future license applications for nuclear waste repositories

  7. Interpolation in Time Series : An Introductive Overview of Existing Methods, Their Performance Criteria and Uncertainty Assessment

    NARCIS (Netherlands)

    Lepot, M.J.; Aubin, Jean Baptiste; Clemens, F.H.L.R.

    2017-01-01

    A thorough review has been performed on interpolation methods to fill gaps in time-series, efficiency criteria, and uncertainty quantifications. On one hand, there are numerous available methods: interpolation, regression, autoregressive, machine learning methods, etc. On the other hand, there are

  8. Drawing students' attention to relevant assessment criteria: effects on self-assessment skills and performance

    NARCIS (Netherlands)

    Fastré, Greet; Van der Klink, Marcel; Sluijsmans, Dominique; Van Merriënboer, Jeroen

    2012-01-01

    Fastré, G. M. J., Van der Klink, M. R., Sluijsmans, D., & Van Merriënboer, J. J. G. (2012). Drawing students’ attention to relevant assessment criteria: effects on self-assessment skills and performance. Journal of Vocational Education & Training, 64(2), 185-198. doi:10.1080/13636820.2011.630537

  9. Functional Performance Measures Used For Return-to-Sport Criteria in Youth Following Lower Extremity Injury.

    Science.gov (United States)

    Powell, Christie; Jensen, Jody; Johnson, Samantha

    2018-02-06

    As sport participation increases globally, so will the injury-related risks. The process used to determine return-to-sport, following injury, is vital to future sport participation and injury prevention. Early specialization along with poor management of sport participation causes an increase in injury risk and potential long-term health consequences for youth athletes. Previous injury is a common intrinsic risk factor for new injuries. Identifying functional performance deficits, defined by return-to-sport criteria, minimizes these risk factors and provides athletes guidelines to return safely to sport. The purpose of this clinical commentary and literature review is to provide a summary of current concepts and clinical practices and identify functional performance measures as clinical assessment tools for return-to-play criteria in the youth population. A literature review was completed using numerous databases where 154 relevant articles were reviewed and 22 articles were included in this commentary. Of the 22 articles using functional performance measures for return-to-sport criteria, six were specific to youth, 12 had mixed populations of adults and youth, and four were normative samples for specific youth populations. The gaps in the literature pertaining to functional performance measures in the youth population are addressed and future research needs for return-to-sport criteria is identified.

  10. Health system professionals, attitude towards necessary criteria for hospitals managers, performance assessment

    Directory of Open Access Journals (Sweden)

    ali janati

    2012-09-01

    Materials and Methods: This study was a qualitative research with thematic analysis method. By using semi structured questionnaire with 2 health system experts interview was conducted and 20 experts participated in focus group discussion. After each interview and group discussion withdrawals were checked with participants. The initial interviews were analyzed by two faculty members and then were combined. Results: 7 main themes about necessary criteria for hospital managers, performance assessment were obtained from experts, views. These themes are: skills related to planning, organization and staff performance management, leadership, information management, clinical governance and performance indicators. Conclusion: All participants in the study had a history of hospital management therefore their comments will be an effective step in identifying the criteria for making hospital managers, performance assessment tool. In addition to Professionals, perspectives and studies done in other countries, in order to design this kind of tools, it is necessary to adjust the obtained findings according to the local hospital conditions.

  11. Development of a business plan for women's health services, using Malcolm Baldrige Performance Excellence Criteria.

    Science.gov (United States)

    Caramanica, L; Maxwell, S; Curry, S

    2000-06-01

    A new process for business planning at Hartford Hospital was needed to achieve critical business results. This article describes the Hospital's use of the Malcolm Baldrige Performance Excellence Criteria as a way to standardize and improve business planning. Women's Health Services is one of Hartford Hospital's "centers for excellence" and one of the first to use these criteria to improve its service. Staff learned how to build their business plan upon a set of core values and concepts such as customer-driven quality, leadership that sets high expectations, continuous improvement and learning, valuing employees, faster response to market demands, management by fact, and a long-range view of the future.

  12. Interpolation in Time Series: An Introductive Overview of Existing Methods, Their Performance Criteria and Uncertainty Assessment

    Directory of Open Access Journals (Sweden)

    Mathieu Lepot

    2017-10-01

    Full Text Available A thorough review has been performed on interpolation methods to fill gaps in time-series, efficiency criteria, and uncertainty quantifications. On one hand, there are numerous available methods: interpolation, regression, autoregressive, machine learning methods, etc. On the other hand, there are many methods and criteria to estimate efficiencies of these methods, but uncertainties on the interpolated values are rarely calculated. Furthermore, while they are estimated according to standard methods, the prediction uncertainty is not taken into account: a discussion is thus presented on the uncertainty estimation of interpolated/extrapolated data. Finally, some suggestions for further research and a new method are proposed.

  13. Comparison Criteria and Performance Levels for Soundproofing Panels Made in Different Constructive Variants

    Directory of Open Access Journals (Sweden)

    Ana Gheorghe

    2013-09-01

    Full Text Available This paper presents an analysis of the performance lavels and comparison criteria for panels made from different soundproofing materials, in different constructive variants. Setting the performance level, on the basis of normative and regulatory documents, for soundproofing materials contained inside of noise reduction devices, is determined so that it can be defined, tested and established feasible technical solutions for sound absorbing protection, through a dissemination of obtained results as well for ensuring requirements for implementing the technology transfer for manufacturing.

  14. Ethnic and social disparities in performance on medical school selection criteria.

    Science.gov (United States)

    Stegers-Jager, Karen M; Steyerberg, Ewout W; Lucieer, Susanna M; Themmen, Axel P N

    2015-01-01

    Medical schools in Western societies seek measures to increase the diversity of their student bodies with respect to ethnicity and social background. Currently, little is known about the effects of different selection procedures on student diversity. This prospective cohort study aimed to determine performance differences between traditional and non-traditional (i.e. ethnic minority and first-generation university candidates) medical school applicants in academic and non-academic selection criteria. Applicants in 2013 (n = 703) were assessed on academic and non-academic selection criteria. They also completed a questionnaire on ethnicity and social background. Main outcome measures were 'not selected' (i.e. failure on any criteria), 'failure on academic criteria' and 'failure on non-academic criteria'. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated by logistic regression analysis for ethnic subgroups (Surinamese/Antillean, Turkish/Moroccan/African, Asian, Western) compared with Dutch applicants, adjusted for age, gender, additional socio-demographic variables (first-generation immigrant, first-generation university applicant, first language, medical doctor as parent) and pre-university grade point average (pu-GPA). Similar analyses were performed for first-generation university applicants. Compared with Dutch applicants, Surinamese/Antillean applicants underperformed in the selection procedure (failure rate: 78% versus 57%; adjusted OR 2.52, 95% CI 1.07-5.94), in particular on academic criteria (failure rate: 66% versus 34%; adjusted OR 3.00, 95% CI 1.41-6.41). The higher failure rate of first-generation university applicants on academic criteria (50% versus 37%; unadjusted OR 1.66, 95% CI 1.18-2.33) was partly explained by additional socio-demographic variables and pu-GPA. The outcome measure 'failure on non-academic criteria' showed no significant differences among the ethnic or social subgroups. The absence of differences on non

  15. A Framework for Human Performance Criteria for Advanced Reactor Operational Concepts

    Energy Technology Data Exchange (ETDEWEB)

    Jacques V Hugo; David I Gertman; Jeffrey C Joe

    2014-08-01

    This report supports the determination of new Operational Concept models needed in support of the operational design of new reactors. The objective of this research is to establish the technical bases for human performance and human performance criteria frameworks, models, and guidance for operational concepts for advanced reactor designs. The report includes a discussion of operating principles for advanced reactors, the human performance issues and requirements for human performance based upon work domain analysis and current regulatory requirements, and a description of general human performance criteria. The major findings and key observations to date are that there is some operating experience that informs operational concepts for baseline designs for SFR and HGTRs, with the Experimental Breeder Reactor-II (EBR-II) as a best-case predecessor design. This report summarizes the theoretical and operational foundations for the development of a framework and model for human performance criteria that will influence the development of future Operational Concepts. The report also highlights issues associated with advanced reactor design and clarifies and codifies the identified aspects of technology and operating scenarios.

  16. A proposed framework for establishing integrated cost and performance criteria for environmental technologies: A summary report

    International Nuclear Information System (INIS)

    1994-05-01

    This document presents a summary of results of a joint EPA/DOE project aimed at establishing a suite of standard cost and performance criteria for evaluating environmental cleanup technologies for DOE sites. Project findings include: (1) decisionmakers have quite different perspectives with interests and information needs varying among decisionmaker groups, (2) previous criteria development efforts may be too narrowly focused to apply to all decisionmakers, (3) criteria must include social/political/economic interests of decisionmakers as well as site-specific variations, and (4) there are 5 core questions that all decisionmakers are likely to ask when considering a technology for use at a site. The resource developed in the project offers decisionmakers a first-time comprehensive assessment of major technology evaluation issues

  17. Containment design, performance criteria and research needs for advanced reactor designs

    International Nuclear Information System (INIS)

    Bagdi, G.; Ali, S.; Costello, J

    2004-01-01

    This paper points out some important shifts in the basic expectations in the performance requirements for containment structures and discusses the areas where the containment structure design requirements and acceptance criteria can be integrated with ultimate test based insights. Although there has not been any new reactor construction in the United States for over thirty years, several designs of evolutionary and advanced reactors have already been certified. Performance requirements for containment structures under design basis and severe accident conditions and explicit consideration of seismic margins have been used in the design certification process. In the United States, the containment structure design code is the American Society of Mechanical Engineers, Boiler and Pressure Vessel Code, Section III, Division 1, Subsection NE-Class MC for the steel containment and Section III, Division 2 for reinforced and prestressed concrete reactor vessels and containments. This containment design code was based on the early concept of applying design basis internal pressure and associated load combinations that included the operating basis and safe shutdown earthquake ground motion. These early design criteria served the nuclear industry and the regulatory authorities in maintaining public health and safety. However, these early design criteria do not incorporate the performance criteria related to containment function in an integrated fashion. Research in large scale model testing of containment structures to failure from over pressurization and shake table testing using simulated ground motion, have produced insights related to failure modes and material behavior at failure. The results of this research provide the opportunity to integrate these observations into design and acceptance criteria. This integration process would identify 'gaps' in the present knowledge and future research needs. This knowledge base is important for gleaning risk-informed insights into

  18. Determination of performance criteria for high-level solidified nuclear waste

    Energy Technology Data Exchange (ETDEWEB)

    Heckman, R.A.; Holdsworth, T.

    1979-05-07

    To minimize radiological risk from the operation of a waste management system, performance limits on volatilization, particulate dispersion, and dissolution characteristics of solidified high level waste must be specified. The results show clearly that the pre-emplacement environs are more limiting in establishing the waste form performance criteria than the post-emplacement environs. Absolute values of expected risk are very sensitive to modeling assumptions. The transportation and interim storage operations appear to be most limiting in determining the performance characteristics required. The expected values of risk do not rely upon the repositories remaining intact over the potentially hazardous lifetime of the waste.

  19. Wind turbine performance: Methods and criteria for reliability of measured power curves

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, D.A. [Advanced Wind Turbines Inc., Seattle, WA (United States)

    1996-12-31

    In order to evaluate the performance of prototype turbines, and to quantify incremental changes in performance through field testing, Advanced Wind Turbines (AWT) has been developing methods and requirements for power curve measurement. In this paper, field test data is used to illustrate several issues and trends which have resulted from this work. Averaging and binning processes, data hours per wind-speed bin, wind turbulence levels, and anemometry methods are all shown to have significant impacts on the resulting power curves. Criteria are given by which the AWT power curves show a high degree of repeatability, and these criteria are compared and contrasted with current published standards for power curve measurement. 6 refs., 5 figs., 5 tabs.

  20. Cumulative prospect theory and second order stochastic dominance criteria: an application to mutual funds performance

    OpenAIRE

    Giuseppe De Nadai; Paolo Pianca

    2007-01-01

    In this note using the rules of stochastic dominance of the second order and the recent cumulative prospect theory for classified, according to their performance, a set of common funds. The criteria used are closely linked to the preferences of decision maker and refer to either hypothesis of aversion and of seeking to risk both hypothesis on the sign of derived second of the function which characterizes the losses and gains.

  1. Multiple criteria for evaluating pollinator performance in highbush blueberry (Ericales: Ericaceae) agroecosystems.

    Science.gov (United States)

    Rogers, Shelley R; Tarpy, David R; Burrack, Hannah J

    2013-12-01

    Numerous bee species provide pollination services in agricultural ecosystems. Evaluating a pollinator's performance with regard to a crop is an important step in attributing pollination services and predicting how changes in a bee community or foraging environment will affect those services. We used multiple criteria to evaluate pollinators of North Carolina highbush blueberry, Vaccinium corymbosum L., agroecosystems. For five groups of bees (Apis mellifera L., Bombus spp., Habropoda laboriosa F., small native bees, and Xylocopa virginica L.), we measured forager abundance through transect observations, quantified per-visit efficiency as viable seed set resulting from a single visit, and analyzed bee presence in different weather conditions. We also considered two other criteria affecting pollinator performance-visitation rate and interspecific influence. A. mellifera was the most abundant bee in the majority of our survey sites, yet had low per-visit efficiency and reduced foraging activity in inclement weather. Small native bees were highly efficient pollinators. Their visits resulted in nearly twice as many seeds as A. mellifera or H. laboriosa. Bombus spp., H. laboriosa, and small native bees were more resilient to fluctuations in temperature, wind speed, and solar radiation than A. mellifera. Although nectar-robbing X. virginica contributed to little pollination through direct flower visits, their presence within the crop impacts the behavior and performance of other individuals. Underscoring the importance of evaluating pollinator performance via multiple criteria, our results show that bee groups contribute to pollination in different ways. These differences may provide functional complementarity and stability of pollination services to agricultural systems.

  2. Student performance during the medical course: role of pre-admission eligibility and selection criteria.

    Science.gov (United States)

    Gupta, Neelima; Nagpal, Gaurav; Dhaliwal, Upreet

    2013-01-01

    Marks scored in class XII determine the eligibility to apply to a medical course in India; selection is through an entrance test. Some students do poorly in the medical course. We assessed the eligibility and selection criteria as predictors of in-course performance. This cross-sectional study included marks in class XII and in each professional examination, and the Delhi University Medical-Dental Entrance Test (DUMET) rank for five batches of medical students. Students were grouped as those who passed professionals in the first attempt and those who did not. Unpaired t-test and Mann-Whitney U test compared class XII marks and mean DUMET scores between the two groups; ROC analysis determined class XII cut-off marks above which no student failed a professional. Students who passed a professional in the first attempt had higher marks in class XII (p0.001). DUMET rank, however, was comparable for the two groups (p>0.05 each). Above a cut-off of 77.8% (in physics, chemistry and biology) students were significantly likely to never fail any professional. Prior academic achievement is a useful measure of in-course performance; however, the current eligibility cut-off results in poor in-course performance by some students. The DUMET is a poor predictor of performance. There is need to reform eligibility and selection criteria to admit students who will do well in the medical course. Copyright 2013, NMJI.

  3. Integrated shape and material selection for single and multi-performance criteria

    International Nuclear Information System (INIS)

    Singh, Jasveer; Mirjalili, Vahid; Pasini, Damiano

    2011-01-01

    Research highlights: → The method of shape transformers is extended to torsional stiffness and combined load design. → The method is generalized for multi-criteria selection of shape and material. → Performance charts are presented for single and multi-objective selection of cross-section shape and material. → A four quadrant performance chart is presented to visualize the relation between objective function space and design variable space. -- Abstract: A shape and material selection method, based on the concept of shape transformers, has been recently introduced to characterize the mass efficiency of lightweight beams under bending and shear. This paper extends this method to deal with the case of torsional stiffness design, and generalize it to single and multi-crieria selection of lightweight shafts subjected to a combination of bending, shear, and torsional load. The novel feature of the paper is the useful integration of shape and material to model and visualize multi-objective selection problems. The scheme is centered on concept selection in structural design, and hinges on measures that govern the shape properties of a cross-section regardless of its size. These measures, referred as shape transformers, can classify shapes in a way similar to material classification. The procedure is exemplified by considering torsional stiffness as a constraint. The performance charts are developed for single and multi-criteria to visualize in a glance the whole range of cross-sectional shapes for each material. Each design chart is explained with a brief example.

  4. Performance criteria for EM rail launchers with solid or transition armatures and laminated rails

    International Nuclear Information System (INIS)

    James, T.E.

    1991-01-01

    Velocity limitations of EM Rail Launchers with solid armatures due to the velocity skin-effect are assessed for a range of homogeneous materials (copper, aluminium, molybdenum and tungsten). Performance criteria as limited by armature melting in the region adjacent to the rail/armature contact surface and by rail surface melting are deduced analytically based on defined electro-thermal reference conditions. The performance criteria predict the reference transition velocity at which the solid contact surface changes to mainly a melted contact surface which is shown to be a fundamental property of the materials. The paper shows that the critical factors in obtaining a high transition velocity are a relatively high resistivity armature material combined with high temperature rail surface coatings. For example a transition velocity of >2.0 km/s for a molybdenum armature and a tungsten rail surface coating on a copper rail are predicted compared with <0.5 km/s for the aluminium/copper combination frequently used

  5. Numerical simulations of crashworthiness performance of multi-cell structures considering damage evolution criteria

    Directory of Open Access Journals (Sweden)

    Estrada Quirino

    2017-01-01

    Full Text Available In this paper finite element software Abaqus was used to analyse the effect of cross-sectional shape on the crashworthiness performance of multi-cell profiles. An emphasis was placed on the modelling of the damage initiation criteria and its evolution during the crash event. The structures evaluated included square and circular multi-cell cross-sections fabricated with aluminium alloy EN AW-7108 T6. During the crash simulations, the structures were subjected to axial impact loads using a 500-kg rigid body striker with an initial velocity of 10 m/s. Accordingly to our results, profiles with circular cross-section base presented better crashworthiness performance than square profiles. An increase in crush force efficiency to 36.9% and specific energy to 35.4% was observed when a circular cross-section has been reinforced in the transversal and longitudinal directions. Finally, it was corroborated that the addition of the damage initiation criteria allowed for more reliable crash simulations of the structures.

  6. Clinical performance of aesthetic restorative materials in primary teeth according to the FDI criteria.

    Science.gov (United States)

    Bektas Donmez, S; Uysal, S; Dolgun, A; Turgut, M D

    2016-09-01

    The purpose of this study is to evaluate the clinical performance of three different restorative materials in primary teeth according to the FDI criteria. Resin-modified glass ionomer cement, compomer and composite resin restorations (n=93) were made in 31 patients. The restorations were clinically evaluated at baseline, 6th, 12th and 18th month with the FDI criteria. The cumulative survival rate after 18 months was found to be 90.3% for resin modified glass ionomer cement restorations, 100% for compomer restorations and 80.6% for composite resin restorations. Statistically significant increase in surface roughness, colour mismatch, anatomic form loss and marginal deterioration were detected in resin- modified glass ionomer group (p<0.05). The most frequent reason for restoration failure in composite resin group was restoration fractures. The resin-modified glass ionomer restorations necessitates close follow-up because of the risk of increase in surface roughness, changes in colour and loss in anatomic form and marginal adaptation. The clinical performance of compomer restorations is superior to resin-modified glass ionomer and composite resin restorations in primary teeth.

  7. Correlations between PANCE performance, physician assistant program grade point average, and selection criteria.

    Science.gov (United States)

    Brown, Gina; Imel, Brittany; Nelson, Alyssa; Hale, LaDonna S; Jansen, Nick

    2013-01-01

    The purpose of this study was to examine correlations between first-time Physician Assistant National Certifying Exam (PANCE) scores and pass/fail status, physician assistant (PA) program didactic grade point average (GPA), and specific selection criteria. This retrospective study evaluated graduating classes from 2007, 2008, and 2009 at a single program (N = 119). There was no correlation between PANCE performance and undergraduate grade point average (GPA), science prerequisite GPA, or health care experience. There was a moderate correlation between PANCE pass/fail and where students took science prerequisites (r = 0.27, P = .003) but not with the PANCE score. PANCE scores were correlated with overall PA program GPA (r = 0.67), PA pharmacology grade (r = 0.68), and PA anatomy grade (r = 0.41) but not with PANCE pass/fail. Correlations between selection criteria and PANCE performance were limited, but further research regarding the influence of prerequisite institution type may be warranted and may improve admission decisions. PANCE scores and PA program GPA correlations may guide academic advising and remediation decisions for current students.

  8. Performance measurement for supply chain management and evaluation criteria determination for reverse supply chain management

    Science.gov (United States)

    Kongar, N. Elif

    2004-12-01

    Today, since customers are able to obtain similar-quality products for similar prices, the lead time has become the only preference criterion for most of the consumers. Therefore, it is crucial that the lead time, i.e., the time spent from the raw material phase till the manufactured good reaches the customer, is minimized. This issue can be investigated under the title of Supply Chain Management (SCM). An efficiently managed supply chain can lead to reduced response time for customers. To achieve this, continuous observation of supply chain efficiency, i.e., a constant performance evaluation of the current SCM is required. Widely used conventional performance measurement methods lack the ability to evaluate a SCM since the supply chain is a dynamic system that requires a more thorough and flexible performance measurement technique. Balanced Scorecard (BS) is an efficient tool for measuring the performance of dynamic systems and has a proven capability of providing the decision makers with the appropriate feedback data. In addition to SCM, a relatively new management field, namely reverse supply chain management (RSCM), also necessitates an appropriate evaluation approach. RSCM differs from SCM in many aspects, i.e., the criteria used for evaluation, the high level of uncertainty involved etc., not allowing the usage of identical evaluation techniques used for SCM. This study proposes a generic Balanced Scorecard to measure the performance of supply chain management while defining the appropriate performance measures for SCM. A scorecard prototype, ESCAPE, is presented to demonstrate the evaluation process.

  9. Determining the microbiological criteria for lot rejection from the performance objective or food safety objective.

    Science.gov (United States)

    Whiting, R C; Rainosek, A; Buchanan, R L; Miliotis, M; Labarre, D; Long, W; Ruple, A; Schaub, S

    2006-08-01

    The Microbiological Criteria (MC) is a set of parameters used to determine whether a specific lot of food is acceptable or not. These parameters are the microbial test protocol and its sensitivity, the confidence level that an unacceptable lot will be detected, the number of samples to be taken and the number of positive samples that are allowed before rejecting the lot. Determining the microbiological criteria begins with knowledge of the distribution of contamination from samples within a lot, particularly within a lot that is just at the unacceptable level of the microbial hazard. The just unacceptable lot can be defined by the Food Safety Objective (FSO) or Performance Objectives (PO), the small fraction of samples that can exceed these values and the standard deviation of the samples from the lot. With this information, a microbial test protocol is chosen to have a sensitivity level that would detect between approximately 15% and 45% of the samples. A confidence level for the MC and the number of positive samples that would be acceptable (c value which is usually zero) are also chosen. With this information the number of samples (n) required can be calculated. A critical factor in setting the microbiological criteria is the sensitivity of the microbiological test (m value). The sample size (weight) and sampling procedure can affect the standard deviation of the samples, particularly foods with non-homogeneous distribution and low numbers of microorganisms. Sampling, sample preparation and analytical procedures that reduce the variation between the samples will affect the choice of m value and maximum lot mean that meets the MC.

  10. Performance analysis of irreversible quantum Stirling cryogenic refrigeration cycles and their parametric optimum criteria

    International Nuclear Information System (INIS)

    Lin Bihong; Chen Jincan

    2006-01-01

    The influence of both the quantum degeneracy and the finite-rate heat transfer between the working substance and the heat reservoirs on the optimal performance of an irreversible Stirling cryogenic refrigeration cycle using an ideal Fermi or Bose gas as the working substance is investigated, based on the theory of statistical mechanics and thermodynamic properties of ideal quantum gases. The inherent regeneration losses of the cycle are analysed. Expressions for several important performance parameters such as the coefficient of performance, cooling rate and power input are derived. By using numerical solutions, the cooling rate of the cycle is optimized for a given power input. The maximum cooling rate and the corresponding parameters are calculated numerically. The optimal regions of the coefficient of performance and power input are determined. In particular, the optimal performance of the cycle in the strong and weak gas degeneracy cases and the high temperature limit are discussed in detail. The analytic expressions of some optimized parameters are derived. Some optimum criteria are given. The distinctions and connections between the Stirling refrigeration cycles working with the ideal quantum and classical gases are revealed

  11. The reference building--one approach in the evolution of building energy performance criteria for houses

    Energy Technology Data Exchange (ETDEWEB)

    Heldenbrand, J.L.; Petersen, S.R.

    1982-12-01

    The reference building approach described in this paper was introduced in the context of the National Bureau of Standards support for the building energy conservation criteria program of the Office of Buildings and Community Systems, U.S. Department of Energy. The role of NBS is to develop technical data and methods for design, construction, and retrofitting of energy efficient buildings. Recent federal initiatives to regulate energy use at the design stage of new buildings support the broadening of performance standards to the whole-building level. A logical means of developing such standards is to provide a methodology for linking component performance standards to the whole-building design-energy-performance level. A side benefit of such a methodology is the assurance that these two paths to building design are consistent and complementary. The ''Reference Building Approach'' (RBA) reported here is one such method. As described here, the RBA approach is not a complete package suitable as a substitute for the Department of Energy's proposed Building Energy Performance Standards (BEPS). However, the paper deals with an element of BEPS and offers a possible improvement to it.

  12. Proposed waste form performance criteria and testing methods for low-level mixed waste

    International Nuclear Information System (INIS)

    Franz, E.M.; Fuhrmann, M.; Bowerman, B.; Bates, S.; Peters, R.

    1994-08-01

    This document describes proposed waste form performance criteria and testing method that could be used as guidance in judging viability of a waste form as a physico-chemical barrier to releases of radionuclides and RCRA regulated hazardous components. It is assumed that release of contaminants by leaching is the single most important property by which the effectiveness of a waste form is judged. A two-tier regimen is proposed. The first tier includes a leach test required by the Environmental Protection Agency and a leach test designed to determine the net forward leach rate for a variety of materials. The second tier of tests are to determine if a set of stresses (i.e., radiation, freeze-thaw, wet-dry cycling) on the waste form adversely impact its ability to retain contaminants and remain physically intact. It is recommended that the first tier tests be performed first to determine acceptability. Only on passing the given specifications for the leach tests should other tests be performed. In the absence of site-specific performance assessments (PA), two generic modeling exercises are described which were used to calculate proposed acceptable leach rates

  13. Chemical Technology Division Comprehensive Self-Assessment and Upgrade Program (CSAUP). Performance Objectives and Criteria

    International Nuclear Information System (INIS)

    1990-05-01

    The U.S. Department of Energy (DOE) has placed strong emphasis on a new way of doing business patterned on the lessons learned in the nuclear power industry after the accident at Three Mile Island Unit 2. The new way relies on strict adherence to policies and procedures, a greatly expanded training program, and much more rigor and formality in operations. Another key element is more visible oversight by upper management and auditability by DOR Although the Chemical Technology Division (Chem Tech) has functioned in a safe manner since its beginning, the policies and methods of the past are no longer appropriate. Therefore, in accordance with these directives, Chem Tech is improving its operational performance by making a transition to greater formality in the observance of policies and procedures and a more deliberate consideration of the interrelationships between organizations at ORNL. This transition to formality is vitally important because both our staff and our facilities are changing with time. For example, some of the inventors and developers of the processes and facilities in use are now ''passing the torch'' to the next generation of Chem Tech staff. Our faculties have also served us well for many years, but the newest of these are now over 20 years old. All have increasing needs of refurbishment and repair, and some of the older ones need to be replaced. The Comprehensive Self-Assessment and Upgrade Program (CSAUP) has been patterned on a similar activity performed at the High Flux Isotope Reactor. Using the Draft DOE Performance Objectives and Criteria for Technical Safety Appraisals (May 1987) as a starting point, it was determined that 14 functional areas for evaluation listed in the report were suitable for Chem Tech use. An additional 5 functional areas were added for completeness since Chem Tech has a broader set of missions than a reactor facility. The Performance Objectives and Criteria (POC) for each functional area in the DOE report were

  14. Neuroimaging criteria and cognitive performance in vascular mild cognitive impairment: A systematic review

    Science.gov (United States)

    Sudo, Felipe Kenji; Alves, Gilberto Sousa; Tiel, Chan; Ericeira-Valente, Letice; Moreira, Denise Madeira; Laks, Jerson; Engelhardt, Eliasz

    2015-01-01

    The recognition of Cerebrovascular Disease (CVD) at earlier clinical stages may favor the control of vascular risk factors and prevention of dementia. However, operational criteria for symptomatic phases at non-dementia stages are often difficult, as the current criteria normally require the evidence of extensive subcortical disease. Objective To identify the neuroimaging profile of Vascular Mild Cognitive Impairment (VaMCI), the impact of those aspects over cognition and the neuropsychological tests that distinguished VaMCI from other groups. Methods Searches were performed in Scopus, ISI and PsycINFO, using the following key terms: "vascular mild cognitive impairment" OR "vascular cognitive impairment no dementia" OR "vascular cognitive impairment not demented" OR "subcortical mild cognitive impairment". Results Of 249 papers, 20 studies were selected. Ten of those included only patients with severe White Matter Hyperintensities (WMH), whereas 10 others admitted subjects with moderate-to-severe WMH. Both groups showed poor performances in Executive Function (EF) tasks in comparison to normal controls and other diagnostic groups. Among EF tests, those assessing "complex" EF abilities consistently distinguished VaMCI from other groups, regardless of the severity of WMH. VaMCI subjects with severe or moderate-to-severe WMH showed cognitive deficits in comparison with other groups. "Complex" EF tests were the most useful in differentiating those patients from the other groups. Conclusion The occurrence of VaMCI may be associated with the presence of CVD at moderate levels; the detection of vascular damage at earlier stages may allow the adoption of therapeutic actions with significant effect-sizes. PMID:29213989

  15. Performance criteria of control rod absorbers of new VVER reactors and a possibility to increase their lifetime

    International Nuclear Information System (INIS)

    Zakharov, A.V.; Risovany, V.D.; Vasilchenko, I.N.; Kurakin, K.Y.; Kushmanov, S.A.; Makhin, V.M.

    2015-01-01

    At present, the lifetime of control rod absorbers of the existing VVER-100 and constructed VVER-1200 is designed to be ten years; they are operated as control rods for three years and as scram rods for seven years. The examination of spent absorbers did not show any degradation in their performance so their lifetime specification might be too conservative. The criteria of the control rod absorbers performance, together with an adequate computational model, can be a methodological basis to develop a system to manage the VVER-1000 control rod absorbers lifetime to fully use their design and material capacities. The criteria for control rod absorbers performance can be split into 5 groups: 1) criteria for physical efficiency, 2) criteria for dynamic characteristics, 3) criteria for radiation resistance, 4) criteria for thermo-mechanical resistance and 5) criteria for corrosion resistance. There is a need in an analytical model to define the neutron-physical and thermo-hydraulic operating conditions as well as thermo-mechanical state of an absorbing element. At present, the key components of the model have been developed (neutron physics and thermo-hydraulics) and the thermo-mechanical model is under development. The analytical models have been used for the justification of a design of absorbing elements combining dysprosium hafnate pellets at the bottom and boron carbide at the top

  16. Multi-criteria group decision making for evaluating the performance of e-waste recycling programs under uncertainty.

    Science.gov (United States)

    Wibowo, Santoso; Deng, Hepu

    2015-06-01

    This paper presents a multi-criteria group decision making approach for effectively evaluating the performance of e-waste recycling programs under uncertainty in an organization. Intuitionistic fuzzy numbers are used for adequately representing the subjective and imprecise assessments of the decision makers in evaluating the relative importance of evaluation criteria and the performance of individual e-waste recycling programs with respect to individual criteria in a given situation. An interactive fuzzy multi-criteria decision making algorithm is developed for facilitating consensus building in a group decision making environment to ensure that all the interest of individual decision makers have been appropriately considered in evaluating alternative e-waste recycling programs with respect to their corporate sustainability performance. The developed algorithm is then incorporated into a multi-criteria decision support system for making the overall performance evaluation process effectively and simple to use. Such a multi-criteria decision making system adequately provides organizations with a proactive mechanism for incorporating the concept of corporate sustainability into their regular planning decisions and business practices. An example is presented for demonstrating the applicability of the proposed approach in evaluating the performance of e-waste recycling programs in organizations. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. ASYMMETRIC PRICE TRANSMISSION MODELING: THE IMPORTANCE OF MODEL COMPLEXITY AND THE PERFORMANCE OF THE SELECTION CRITERIA

    Directory of Open Access Journals (Sweden)

    Henry de-Graft Acquah

    2013-01-01

    Full Text Available Information Criteria provides an attractive basis for selecting the best model from a set of competing asymmetric price transmission models or theories. However, little is understood about the sensitivity of the model selection methods to model complexity. This study therefore fits competing asymmetric price transmission models that differ in complexity to simulated data and evaluates the ability of the model selection methods to recover the true model. The results of Monte Carlo experimentation suggest that in general BIC, CAIC and DIC were superior to AIC when the true data generating process was the standard error correction model, whereas AIC was more successful when the true model was the complex error correction model. It is also shown that the model selection methods performed better in large samples for a complex asymmetric data generating process than with a standard asymmetric data generating process. Except for complex models, AIC's performance did not make substantial gains in recovery rates as sample size increased. The research findings demonstrate the influence of model complexity in asymmetric price transmission model comparison and selection.

  18. Extrapolating power-ramp performance criteria for current and advanced CANDU fuels

    International Nuclear Information System (INIS)

    Tayal, M.; Chassie, G.G.

    2000-06-01

    To improve the precision and accuracy of power-ramp performance criteria for high-burnup fuel, we have examined in-reactor fuel performance data as well as out-reactor test data. The data are consistent with some of the concepts used in the current formulations for defining fuel failure thresholds, such as size of power-ramp and extent of burnup. Our review indicates that there is a need to modify some other aspects of the current formulations; therefore, a modified formulation is presented in this paper. The improvements mainly concern corrodent concentration and its relationships with threshold stress for failure. The new formulation is consistent with known and expected trends such as strength of Zircaloy in corrosive environment, timing of the release of fission products to the pellet-to-sheath gap, CANLUB coating, and fuel burnup. Because of the increased precision and accuracy, the new formulation is better able to identify operational regimes that are at risk of power-ramp failures; this predictive ability provides enhanced protection to fuel against power-ramp defects. At die same time, by removing unnecessary conservatisms in other areas, the new formulation permits a greater range of defect-free operational envelope as well as larger operating margins in regions that are, in fact, not prone to power-ramp failures. (author)

  19. Diagnostic Performance of Three Phase Bone Scan for Complex Regional Pain Syndrome Type 1 with Optimally Modified Image Criteria

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Hyun Woo; Paeng, Jin Chul; Nahm, Francins Sahngun; Kim, Seog Gyun; Zehra, Tanzeel; Oh, So Won; Lee, Hyo Sang; Kang, Keon Wook; Chung, June Key; Lee, Myung Chul; Lee, Dong Soo [Seoul National Univ. College of Medicine, Seoul (Korea, Republic of)

    2011-12-15

    Although the three phase bone scan (TBPS) is one of the widely used imaging studies for diagnosing complex regional pain syndrome type 1 (CRPS 1), there is some controversy regarding the TPBS image criteria for CRPS 1. In this study, we modified the image criteria using image pattern and quantitative analysis in the patients diagnosed using the most recent consensus clinical diagnostic criteria. The study included 140 patients with suspected CRPS 1 (CRPS 1, n=79; non CRPS, n=61; mean age 39{+-}15 years) who underwent TPBS. The clinical diagnostic criteria for CRPS 1 revised by the Budapest consensus group were used for confirmative diagnosis. Patients were classified according to flow/pool and delayed uptake (DU) image patterns, and the time interval between the initiating event and TPBS (TI{sup eventscan)}. Quantitative analysis for lesion to contralateral ratio (LCR) was performed. Modified TPBS image criteria were created and evaluated for optimal diagnostic performance. Both increased and decreased periarticular DU were significant image findings for CRPS 1 (CRPS 1 positive rate=73% in the increased DU group, 75% in the decreased DU group). The TI{sup eventscand}id not differ significantly between the different image pattern groups. Quantitative analysis revealed an LCR of 1.43 was the optimal cutoff value for CRPS 1 and diagnostic performance was significantly improved in the increased DU group (area under the curve=0.732). Given the modified image criteria, the sensitivity and specificity of TPBS for diagnosing CRPS 1 were 80% and 72%, respectively. Optimally modified TPBS image criteria for CRPS 1 were suggested using image pattern and quantitative analysis. With the criteria, TPBS is an effective imaging study for CRPS 1 even with the most recent consensus clinical diagnostic criteria.

  20. Diagnostic Performance of Three Phase Bone Scan for Complex Regional Pain Syndrome Type 1 with Optimally Modified Image Criteria

    International Nuclear Information System (INIS)

    Kwon, Hyun Woo; Paeng, Jin Chul; Nahm, Francins Sahngun; Kim, Seog Gyun; Zehra, Tanzeel; Oh, So Won; Lee, Hyo Sang; Kang, Keon Wook; Chung, June Key; Lee, Myung Chul; Lee, Dong Soo

    2011-01-01

    Although the three phase bone scan (TBPS) is one of the widely used imaging studies for diagnosing complex regional pain syndrome type 1 (CRPS 1), there is some controversy regarding the TPBS image criteria for CRPS 1. In this study, we modified the image criteria using image pattern and quantitative analysis in the patients diagnosed using the most recent consensus clinical diagnostic criteria. The study included 140 patients with suspected CRPS 1 (CRPS 1, n=79; non CRPS, n=61; mean age 39±15 years) who underwent TPBS. The clinical diagnostic criteria for CRPS 1 revised by the Budapest consensus group were used for confirmative diagnosis. Patients were classified according to flow/pool and delayed uptake (DU) image patterns, and the time interval between the initiating event and TPBS (TI eventscan) . Quantitative analysis for lesion to contralateral ratio (LCR) was performed. Modified TPBS image criteria were created and evaluated for optimal diagnostic performance. Both increased and decreased periarticular DU were significant image findings for CRPS 1 (CRPS 1 positive rate=73% in the increased DU group, 75% in the decreased DU group). The TI eventscand id not differ significantly between the different image pattern groups. Quantitative analysis revealed an LCR of 1.43 was the optimal cutoff value for CRPS 1 and diagnostic performance was significantly improved in the increased DU group (area under the curve=0.732). Given the modified image criteria, the sensitivity and specificity of TPBS for diagnosing CRPS 1 were 80% and 72%, respectively. Optimally modified TPBS image criteria for CRPS 1 were suggested using image pattern and quantitative analysis. With the criteria, TPBS is an effective imaging study for CRPS 1 even with the most recent consensus clinical diagnostic criteria.

  1. Sensitivity tests to define the source apportionment performance criteria in the DeltaSA tool

    Science.gov (United States)

    Pernigotti, Denise; Belis, Claudio A.

    2017-04-01

    Identification and quantification of the contribution of emission sources to a given area is a key task for the design of abatement strategies. Moreover, European member states are obliged to report this kind of information for zones where the pollution levels exceed the limit values. At present, little is known about the performance and uncertainty of the variety of methodologies used for source apportionment and the comparability between the results of studies using different approaches. The source apportionment Delta (SA Delta) is a tool developed by the EC-JRC to support the particulate matter source apportionment modellers in the identification of sources (for factor analysis studies) and/or in the measure of their performance. The source identification is performed by the tool measuring the proximity of any user chemical profile to preloaded repository data (SPECIATE and SPECIEUROPE). The model performances criteria are based on standard statistical indexes calculated by comparing participants' source contribute estimates and their time series with preloaded references data. Those preloaded data refer to previous European SA intercomparison exercises: the first with real world data (22 participants), the second with synthetic data (25 participants) and the last with real world data which was also extended to Chemical Transport Models (38 receptor models and 4 CTMs). The references used for the model performances are 'true' (predefined by JRC) for the synthetic while they are calculated as ensemble average of the participants' results in real world intercomparisons. The candidates used for each source ensemble reference calculation were selected among participants results based on a number of consistency checks plus the similarity between their chemical profiles to the repository measured data. The estimation of the ensemble reference uncertainty is crucial in order to evaluate the users' performances against it. For this reason a sensitivity analysis on

  2. Performance of different diagnostic criteria of overweight and obesity as predictors of metabolic syndrome in adolescents

    Directory of Open Access Journals (Sweden)

    Raphael Gonçalves de Oliveira

    2017-09-01

    Conclusions: Overweight and obesity using BMI showed a moderate association with MetS, regardless of the diagnostic criteria used. However, the IOTF criterion showed better predictive capacity for the presence of MetS than the WHO and the Conde and Monteiro criteria.

  3. Development of performance assessment methodology for establishment of quantitative acceptance criteria of near-surface radioactive waste disposal

    Energy Technology Data Exchange (ETDEWEB)

    Kim, C. R.; Lee, E. Y.; Park, J. W.; Chang, G. M.; Park, H. Y.; Yeom, Y. S. [Korea Hydro and Nuclear Power Co., Ltd., Seoul (Korea, Republic of)

    2002-03-15

    The contents and the scope of this study are as follows : review of state-of-the-art on the establishment of waste acceptance criteria in foreign near-surface radioactive waste disposal facilities, investigation of radiological assessment methodologies and scenarios, investigation of existing models and computer codes used in performance/safety assessment, development of a performance assessment methodology(draft) to derive quantitatively radionuclide acceptance criteria of domestic near-surface disposal facility, preliminary performance/safety assessment in accordance with the developed methodology.

  4. Performance Based Failure Criteria of the Base Isolation System for Nuclear Power Plants

    International Nuclear Information System (INIS)

    Kim, Jung Han; Kim, Min Kyu; Choi, In Kil

    2013-01-01

    The realistic approach to evaluate the failure state of the base isolation system is necessary. From this point of view, several concerns are reviewed and discussed in this study. This is the preliminary study for the performance based risk assessment of a base isolated nuclear power plant. The items to evaluate the capacity and response of an individual base isolator and a base isolation system were briefly outlined. However, the methodology to evaluate the realistic fragility of a base isolation system still needs to be specified. For the quantification of the seismic risk for a nuclear power plant structure, the failure probabilities of the structural component for the various seismic intensity levels need to be calculated. The failure probability is evaluated as the probability when the seismic response of a structure exceeds the failure criteria. Accordingly, the failure mode of the structural system caused by an earthquake vibration should be defined first. The type of a base isolator appropriate for a nuclear power plant structure is regarded as an elastometric rubber bearing with a lead core. The failure limit of the lead-rubber bearing (LRB) is not easy to be predicted because of its high nonlinearity and a complex loading condition by an earthquake excitation. Furthermore, the failure mode of the LRB system installed below the nuclear island cannot be simply determined because the basemat can be sufficiently supported if the number of damaged isolator is not much

  5. Monitoring performance of progression assessment criteria for cancer antigen 125 among patients with ovarian cancer compared by computer simulation

    DEFF Research Database (Denmark)

    Abu Hassan, Suher Othman; Petersen, Per Hyltoft; Lund, Flemming

    2015-01-01

    BACKGROUND: Cancer antigen 125 (CA125) is used to monitor tumor burden among patients with advanced serous epithelial ovarian cancer. The purpose is to compare the monitoring performance of seven previously proposed criteria. MATERIALS & METHODS: The CA125 assessment criteria were applied...... to simulated datasets. We investigated the ability to provide information on CA125 increments as well as their robustness against false positive signals. RESULTS: For baseline concentrations above cut-off, the best performing criterion was based on a confirmed increment ≥2.5-times the nadir concentration...

  6. 49 CFR Appendix B to Part 238 - Test Methods and Performance Criteria for the Flammability and Smoke Emission Characteristics of...

    Science.gov (United States)

    2010-10-01

    ..., and Laminated Apparel Fabrics. (iii) ASTM D 3574-95, Standard Test Methods for Flexible Cellular..., fabric layers, upholstery) according to ASTM E 1537-99 using the pass/fail criteria of Cal TB 133, and... equivalent fire performance properties to the original components tested. A fire hazard analysis must also be...

  7. Performance of classification criteria for gout in early and established disease

    DEFF Research Database (Denmark)

    Taylor, William J; Fransen, Jaap; Dalbeth, Nicola

    2016-01-01

    OBJECTIVES: To compare the sensitivity and specificity of different classification criteria for gout in early and established disease. METHODS: This was a cross-sectional study of consecutive rheumatology clinic patients with joint swelling in which gout was defined by presence or absence of mono...

  8. Collaborative Design of Assessment Criteria to Improve Undergraduate Student Engagement and Performance

    Science.gov (United States)

    Leslie, Laura J.; Gorman, Paul C.

    2017-01-01

    Student engagement is vital in enhancing the student experience and encouraging deeper learning. Involving students in the design of assessment criteria is one way in which to increase student engagement. In 2011, a marking matrix was used at Aston University (UK) for logbook assessment (Group One) in a project-based learning module. The next…

  9. 77 FR 58607 - Office of Commercial Space Transportation Safety Approval Performance Criteria

    Science.gov (United States)

    2012-09-21

    ...: Notification of criteria used to evaluate the National Aerospace Training and Research (NASTAR) Center safety... approval for the ability of its Falcon 12/4 Altitude Chamber to replicate pressures experienced at altitude...). NASTAR's Falcon 12/4 Altitude Chamber is capable of replicating any pressure experienced at altitudes...

  10. 78 FR 28275 - Office of Commercial Space Transportation; Safety Approval Performance Criteria

    Science.gov (United States)

    2013-05-14

    ... provide as a service, scenario based physiology training, which includes hypobaric chamber training. BST may offer its scenario based physiology altitude training as a service to a prospective launch and...: Notification of criteria used to evaluate the Black Sky Training, Inc. (BST) safety approval application...

  11. Application Criteria for Nine-Switch Power Conversion Systems with Improved Thermal Performance

    DEFF Research Database (Denmark)

    Qin, Zian; Loh, Poh Chiang; Blaabjerg, Frede

    2015-01-01

    -switch converter can at times be lower than the twelve-switch back-to-back converter. The scope of this paper is thus to identify application criteria for the nine-switch converter, which upon met, will lead to lower conduction and hence total losses. Loss distribution among switches of the nine-switch converter...

  12. A conceptual framework for a sports knee injury performance profile (SKIPP and return to activity criteria (RTAC

    Directory of Open Access Journals (Sweden)

    David Logerstedt

    2015-10-01

    Full Text Available ABSTRACTInjuries to the knee, including intra-articular fractures, ligamentous ruptures, and meniscal and articular cartilage lesions, are commonplace within sports. Despite advancements in surgical techniques and enhanced rehabilitation, athletes returning to cutting, pivoting, and jumping sports after a knee injury are at greater risk of sustaining a second injury. The clinical utility of objective criteria presents a decision-making challenge to ensure athletes are fully rehabilitated and safe to return to sport. A system centered on specific indicators that can be used to develop a comprehensive profile to monitor rehabilitation progression and to establish return to activity criteria is recommended to clear athletes to begin a progressive and systematic approach to activities and sports. Integration of a sports knee injury performance profile with return to activity criteria can guide clinicians in facilitating an athlete's safe return to sport, prevention of subsequent injury, and life-long knee joint health.

  13. A conceptual framework for a sports knee injury performance profile (SKIPP) and return to activity criteria (RTAC).

    Science.gov (United States)

    Logerstedt, David; Arundale, Amelia; Lynch, Andrew; Snyder-Mackler, Lynn

    2015-01-01

    Injuries to the knee, including intra-articular fractures, ligamentous ruptures, and meniscal and articular cartilage lesions, are commonplace within sports. Despite advancements in surgical techniques and enhanced rehabilitation, athletes returning to cutting, pivoting, and jumping sports after a knee injury are at greater risk of sustaining a second injury. The clinical utility of objective criteria presents a decision-making challenge to ensure athletes are fully rehabilitated and safe to return to sport. A system centered on specific indicators that can be used to develop a comprehensive profile to monitor rehabilitation progression and to establish return to activity criteria is recommended to clear athletes to begin a progressive and systematic approach to activities and sports. Integration of a sports knee injury performance profile with return to activity criteria can guide clinicians in facilitating an athlete's safe return to sport, prevention of subsequent injury, and life-long knee joint health.

  14. Achievement of VO2max criteria during a continuous graded exercise test and a verification stage performed by college athletes.

    Science.gov (United States)

    Mier, Constance M; Alexander, Ryan P; Mageean, Amanda L

    2012-10-01

    The purpose of this study was to determine the incidence of meeting specific VO2max criteria and to test the effectiveness of a VO2max verification stage in college athletes. Thirty-five subjects completed a continuous graded exercise test (GXT) to volitional exhaustion. The frequency of achieving various respiratory exchange ratio (RER) and age-predicted maximum heart rate (HRmax) criteria and a VO2 plateau within 2 and 2.2 ml·kg(-1)·min(-1) (active recovery, 10 subjects who did not demonstrate a plateau completed a verification stage performed at supramaximal intensity. From the GXT, the number of subjects meeting VO2max plateau was 5 (≤2 ml·kg(-1)·min(-1)) and 7 (≤2.2 ml·kg(-1)·min(-1)), RER criteria 34 (≥1.05), 32 (≥1.10), and 24 (≥1.15), HRmax criteria, 35 (athlete's ability to achieve VO2max plateau and certain RER and HR criteria. The use of a verification stage increases the frequency of VO2max achievement and may be an effective method to improve the accuracy of VO2max measurements in college athletes.

  15. Multi-Criteria Evaluation of End-of-Life Vehicles’ Dismantling Scenarios with Respect to Technical Performance and Sustainability Issues

    Directory of Open Access Journals (Sweden)

    Alexis Schmid

    2016-12-01

    Full Text Available Three scenarios of dismantling and shredding operations of end-of-life vehicles (ELVs were compared in this study with respect to technical and sustainability criteria, according to the level of dismantling applied to the vehicles. The scenarios differed from each other in the extent of the dismantling operations. They were implemented experimentally at the industrial scale on representative samples of 120 vehicles. The data collected from the monitoring of the experimental campaigns were used as feed data for the multi-criteria analysis of the scenarios using the PROMETHEE method. Nine criteria of evaluation were selected, namely global warming, local environmental impacts, tropospheric ozone production, ecotoxicity, operational costs, investment costs, occupational risks, employability, and technical performance. The medium-level dismantling scenario was identified as the best scenario with respect to the criteria of evaluation. This scenario included the steps of depollution, followed by the removal of easily accessible and identifiable plastics and glasses. Reasonable changes in the ponderation of the evaluation criteria did not significantly affect the ranking.

  16. A comparative study on the ranking performance of some multi-criteria decision-making methods for industrial robot selection

    Directory of Open Access Journals (Sweden)

    Vijay Manikrao Athawale

    2011-10-01

    Full Text Available Industrial robots are mainly employed to perform repetitive and hazardous production jobs, multi-shift operations etc. to reduce the delivery time, improve the work environment, lower the production cost and even increase the product range to fulfill the customers’ needs. When a choice is to be made from among several alternative robots for a given industrial application, it is necessary to compare their performance characteristics in a decisive way. As the industrial robot selection problem involves multiple conflicting criteria and a finite set of candidate alternatives, different multi-criteria decision-making (MCDM methods can be effectively used to solve such type of problem. In this paper, ten most popular MCDM methods are considered and their relative performance are compared with respect to the rankings of the alternative robots as engaged in some industrial pick-n-place operation. It is observed that all these methods give almost the same rankings of the alternative robots, although the performance of WPM, TOPSIS and GRA methods are slightly better than the others. It can be concluded that for a given industrial robot selection problem, more attention is to be paid on the proper selection of the relevant criteria and alternatives, not on choosing the most appropriate MCDM method to be employed.

  17. The diagnostic performance of radiographic criteria to detect aseptic acetabular component loosening after revision total hip arthroplasty.

    Science.gov (United States)

    Abrahams, J M; Kim, Y S; Callary, S A; De Ieso, C; Costi, K; Howie, D W; Solomon, L B

    2017-04-01

    This study aimed to determine the diagnostic performance of radiographic criteria to detect aseptic acetabular loosening after revision total hip arthroplasty (THA). Secondary aims were to determine the predictive values of different thresholds of migration and to determine the predictive values of radiolucency criteria. Acetabular component migration to re-revision was measured retrospectively using Ein-Bild-Rontgen-Analyse (EBRA-Cup) and manual measurements (Sutherland method) in two groups: Group A, 52 components (48 patients) found not loose at re-revision and Group B, 42 components (36 patients) found loose at re-revision between 1980 and 2015. The presence and extent of radiolucent lines was also assessed. Using EBRA, both proximal translation and sagittal rotation were excellent diagnostic tests for detecting aseptic loosening. The area under the receiver operating characteristic (ROC) curves was 0.94 and 0.93, respectively. The thresholds of 2.5 mm proximal translation or 2° sagittal rotation (EBRA) in combination with radiolucency criteria had a sensitivity of 93% and specificity of 88% to detect aseptic loosening. The sensitivity, specificity, positive predictive value and negative predictive value (NPV) of radiolucency criteria were 41%, 100%, 100% and 68% respectively. Manual measurements of both proximal translation and sagittal rotation were very good diagnostic tests. The area under the ROC curve was 0.86 and 0.92 respectively. However, manual measurements had a decreased specificity compared with EBRA. Radiolucency criteria had a poor sensitivity and NPV of 41% and 68% respectively. This study shows that EBRA and manual migration measurements can be used as accurate diagnostic tools to detect aseptic loosening of cementless acetabular components used at revision THA. Radiolucency criteria should not be used in isolation to exclude loosening of cementless acetabular components used at revision THA given their poor sensitivity and NPV. Cite this

  18. Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Encoded mRNases

    DEFF Research Database (Denmark)

    Tian, Chengzhe; Roghanian, Mohammad; Jørgensen, Mikkel Girke

    2016-01-01

    Escherichia coli regulates its metabolism to adapt to changes in the environment, in particular to stressful downshifts in nutrient quality. Such shifts elicit the so-called stringent response coordinated by the alarmone guanosine tetra- and pentaphosphate [(p)ppGpp]. At sudden amino-acid (aa......RNase-encoding TA modules present in the wt strain. This observation suggested that toxins are part of the negative feedback to control the (p)ppGpp level during early stringent response. We built a ribosome trafficking model to evaluate the fold of increase in the RelA activity just after the onset of aa...... %. IMPORTANCE: The early stringent response elicited by amino-acid starvation is controlled by a sharp increase of the cellular (p)ppGpp level. Toxin-antitoxin encoded mRNases are activated by (p)ppGpp through enhanced degradation of antitoxins. The present work shows that this activation happens at a very...

  19. Phylogenetic analysis of proteins involved in the stringent response in plant cells.

    Science.gov (United States)

    Ito, Doshun; Ihara, Yuta; Nishihara, Hidenori; Masuda, Shinji

    2017-07-01

    The nucleotide (p)ppGpp is a second messenger that controls the stringent response in bacteria. The stringent response modifies expression of a large number of genes and metabolic processes and allows bacteria to survive under fluctuating environmental conditions. Recent genome sequencing analyses have revealed that genes responsible for the stringent response are also found in plants. These include (p)ppGpp synthases and hydrolases, RelA/SpoT homologs (RSHs), and the pppGpp-specific phosphatase GppA/Ppx. However, phylogenetic relationship between enzymes involved in bacterial and plant stringent responses is as yet generally unclear. Here, we investigated the origin and evolution of genes involved in the stringent response in plants. Phylogenetic analysis and primary structures of RSH homologs from different plant phyla (including Embryophyta, Charophyta, Chlorophyta, Rhodophyta and Glaucophyta) indicate that RSH gene families were introduced into plant cells by at least two independent lateral gene transfers from the bacterial Deinococcus-Thermus phylum and an unidentified bacterial phylum; alternatively, they were introduced into a proto-plant cell by a lateral gene transfer from the endosymbiotic cyanobacterium followed by gene loss of an ancestral RSH gene in the cyanobacterial linage. Phylogenetic analysis of gppA/ppx families indicated that plant gppA/ppx homologs form an individual cluster in the phylogenetic tree, and show a sister relationship with some bacterial gppA/ppx homologs. Although RSHs contain a plastidial transit peptide at the N terminus, GppA/Ppx homologs do not, suggesting that plant GppA/Ppx homologs function in the cytosol. These results reveal that a proto-plant cell obtained genes for the stringent response by lateral gene transfer events from different bacterial phyla and have utilized them to control metabolism in plastids and the cytosol.

  20. Observer Variability and the Performance between Faculties and Residents: US Criteria for Benign and Malignant Thyroid Nodules

    International Nuclear Information System (INIS)

    Kim, Sung Hun; Park, Chang Suk; Jung, So Lyung

    2010-01-01

    To evaluate the interobserver variability and performance in the interpretation of ultrasonographic (US) findings of thyroid nodules. 72 malignant nodules and 61 benign nodules were enrolled as part of this study. Five faculty radiologists and four residents independently performed a retrospective analysis of the US images. The observers received one training session after the first interpretation and then performed a secondary interpretation. Agreement was analyzed by Cohen's kappa statistic. Degree of performance was analyzed using receiver operating characteristic (ROC) curves. Agreement between the faculties was fair-to-good for all criteria; however, between residents, agreement was poor-to-fair. The area under the ROC curves was 0.72, 0.62, and 0.60 for the faculties, senior residents, and junior residents, respectively. There was a significant difference in performance between the faculties and the residents (p < 0.05). There was a significant increase in the agreement for some criteria in the faculties and the senior residents after the training session, but no significant increase in the junior residents. Independent reporting of thyroid US performed by residents is undesirable. A continuous and specialized resident training is essential to enhance the degree of agreement and performance

  1. A BSC- EFQM method for evaluating and detecting performance measurement criteria: A case study of Malavan Footbal team

    Directory of Open Access Journals (Sweden)

    Heydar Shojaee Vazhnani

    2013-08-01

    Full Text Available This paper presents an empirical investigation to find important criteria for performance measurement based on two methods of balanced score card (BSC as well as European Foundation of Quality Management (EFQM methods. In order to determine the mission, vision, strategy and values we first review different documents including International Federation of football documentations, AFC and Football Federation of the Islamic Republic of Iran and Charter Club. Next, we determine the necessary criteria for performance measurement using interview with decision makers, design a questionnaire and distribute it among 57 players and coaching staff as well as experts, veterans and supporters club. Next, we study the results using t-student test and analyze them. The results are categorized in terms of four criteria of BSC method including internal processes, learning and growth, costumer and financial. In addition, key performance results based on the Excellence Model are classified according to nine areas of leadership, strategy, human resources, partnerships and resources, processes, customer results, human resource results and society.

  2. Utilizing an ANP framework for prioritizing effective criteria on performance management in cooperative organization

    Directory of Open Access Journals (Sweden)

    Hosein Akhavan Alavi

    2012-09-01

    Full Text Available Performance management plays an essential role on increasing efficiency of business units. It helps find important barriers against a business unit helping us setup better strategies for handling troubles. In this paper, we present an empirical study to find important factors influencing performance management in cooperative organizations. The proposed study uses analytical hierarchy process to rank important factors in three groups of team level, individual and organization levels. The survey is based on receiving feedbacks from decision makers and making a pairwise comparison on measuring the relative importance of each criterion influencing performance management. The results of our survey indicate that setting appropriate standards for performance management is the most important item followed by relationship between organization structure and performance management, performance management based on future events. The other three factors including continuous improvement and updating systems, encouraging employee for change culture and relationship between future outlook and performance management are other important factors.

  3. NF ISO 12790-1. Radiation protection. Performance criteria for the radio-toxicologic analysis. Part 1: general principles

    International Nuclear Information System (INIS)

    2002-03-01

    This standard document deals with: the exactness of the in-vivo direct measurements of the activity and quantity of the main radionuclides selected for ghost-tests, and the exactness of the indirect in-vitro measurements performed on test samples; the methods of determination of the minimum detectable quantity; the minimum levels of tests and their range; the radio-toxicology reports made by laboratories of medical biology analysis; the quality assurance in such laboratories; the protocol of transmission of test evaluation results; the by-default mode of operation when no performance criteria are precised. (J.S.)

  4. The stringent response regulates adaptation to darkness in the cyanobacterium Synechococcus elongatus.

    Science.gov (United States)

    Hood, Rachel D; Higgins, Sean A; Flamholz, Avi; Nichols, Robert J; Savage, David F

    2016-08-16

    The cyanobacterium Synechococcus elongatus relies upon photosynthesis to drive metabolism and growth. During darkness, Synechococcus stops growing, derives energy from its glycogen stores, and greatly decreases rates of macromolecular synthesis via unknown mechanisms. Here, we show that the stringent response, a stress response pathway whose genes are conserved across bacteria and plant plastids, contributes to this dark adaptation. Levels of the stringent response alarmone guanosine 3'-diphosphate 5'-diphosphate (ppGpp) rise after a shift from light to dark, indicating that darkness triggers the same response in cyanobacteria as starvation in heterotrophic bacteria. High levels of ppGpp are sufficient to stop growth and dramatically alter many aspects of cellular physiology, including levels of photosynthetic pigments and polyphosphate, DNA content, and the rate of translation. Cells unable to synthesize ppGpp display pronounced growth defects after exposure to darkness. The stringent response regulates expression of a number of genes in Synechococcus, including ribosomal hibernation promoting factor (hpf), which causes ribosomes to dimerize in the dark and may contribute to decreased translation. Although the metabolism of Synechococcus differentiates it from other model bacterial systems, the logic of the stringent response remains remarkably conserved, while at the same time having adapted to the unique stresses of the photosynthetic lifestyle.

  5. Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family

    DEFF Research Database (Denmark)

    Kristensen, Ole; Laurberg, Martin; Liljas, Anders

    2004-01-01

    Exopolyphosphatase/guanosine pentaphosphate phosphohydrolase (PPX/GPPA) enzymes play central roles in the bacterial stringent response induced by starvation. The high-resolution crystal structure of the putative Aquifex aeolicus PPX/GPPA phosphatase from the actin-like ATPase domain superfamily h...

  6. Admissions Criteria as Predictors of Academic Performance in a Three-Year Pharmacy Program at a Historically Black Institution

    Science.gov (United States)

    Parmar, Jayesh R.; Purnell, Miriam; Lang, Lynn A.

    2016-01-01

    Objective. To determine the ability of University of Maryland Eastern Shore School of Pharmacy’s admissions criteria to predict students’ academic performance in a 3-year pharmacy program and to analyze transferability to African-American students. Methods. Statistical analyses were conducted on retrospective data for 174 students. Didactic and experiential scores were used as measures of academic performance. Results. Pharmacy College Admission Test (PCAT), grade point average (GPA), interview, and observational scores combined with previous pharmacy experience and biochemistry coursework predicted the students' academic performance except second-year (P2) experiential performance. For African-American students, didactic performance positively correlated with PCAT writing subtests, while the experiential performance positively correlated with previous pharmacy experience and observational score. For nonAfrican-American students, didactic performance positively correlated with PCAT multiple-choice subtests, and experiential performance with interview score. The prerequisite GPA positively correlated with both of the student subgroups’ didactic performance. Conclusion. Both PCAT and GPA were predictors of didactic performance, especially in nonAfrican-Americans. Pharmacy experience and observational scores were predictors of experiential performance, especially in African-Americans. PMID:26941432

  7. IMPROVEMENT OF THE ASSESSMENT CRITERIA FOR SCIENTIFIC RESEARCH PROJECTS - A PREMISE OF INCREASING THE UNIVERSITY SCIENTIFIC RESEARCH PERFORMANCE

    Directory of Open Access Journals (Sweden)

    Cristian Marius TOMA

    2013-10-01

    Full Text Available The National Plan for Research, Development and Innovation 2007 – 2013, called herein the National Plan II, represents the main instrument used to implement the National Strategy for Research, Development and Innovation. Universities play a unique role in the development of the knowledge-based society, through its contribution to knowledge generation, transmission, dissemination and utilization. The essential role of the university is to shape the highly qualified human resource, a process that implies a symbiosis between the education and research, the education system performances contributing in this way to a great extent to the society development. The highly qualified human resource represents an important asset of a nation. This study is dedicated to the analysis of the assessment criteria for the Exploratory Research Projects (ERP handed in the competitions in 2007, 2008, 2011 and 2012 and to highlight the importance of improving the assessment criteria in order to improve their quality.

  8. A fuzzy multi criteria approach for measuring sustainability performance of a supplier based on triple bottom line approach

    DEFF Research Database (Denmark)

    Govindan, Kannan; Khodaverdi, R.; Jafarian, A.

    2013-01-01

    . Traditionally, organizations consider criteria such as price, quality, flexibility, etc. when evaluating supplier performance. While the articles on the selection and evaluation of suppliers are abundant, those that consider sustainability issues are rather limited. This paper explores sustainable supply chain...... responsibility. Sustainable supply chain initiatives like supplier environmental and social collaboration can play a significant role in achieving the "triple bottom line" of social, environmental, and economic benefits. Supplier selection plays an important role in the management of a supply chain...... initiatives and examines the problem of identifying an effective model based on the Triple Bottom Line (TBL) approach (economic, environmental, and social aspects) for supplier selection operations in supply chains by presenting a fuzzy multi criteria approach. We use triangular fuzzy numbers to express...

  9. PERFORMANCE CRITERIA of RUBBER UKM BASED ON COOPERATIVE USING BALANCED SCORECARD METHOD

    Directory of Open Access Journals (Sweden)

    Dessy Iriani Putri

    2017-01-01

    Full Text Available Small and Medium Enterprises (UKM of Usaha Mandiri is the only UKM in Putri Hijau district, North Bengkulu that carries out its activities based on cooperative principles. The UKM was established in 2010 due to the rubber farmer’s concern about their future. In the last few years, the rubber price has declined, resulting in the decreasing performance of UKM Usaha Mandiri’s.  The objective of this research is to analyze the performance of UKM of Usaha Mandiri.  The method used is balanced scorecard (BSC and Focus Group Discussion (FGD to identify the UKM’s strategic aim and the BSC value. The result of the research shows that the performance of UKM of Usaha Mandiri   started to decline from 2013–2015.  The BSC score from 2011–2015 was 112.93 (excellent, 141.84 (excellent, 95.41 (excellent, 47.42 (average and 81.62 (very good.  The decline of the performance was due to the decline of natural rubber price.  The conclusion for the research is that in 2015 the performance of UKM of Usaha Mandiri   was categorized as very good (BSC method with the most contribution from growth and learning perspective.        Keywords : Balanced scorecard, BSC, cooperation, performance measurement, UKM

  10. Improving behavioral performance under full attention by adjusting response criteria to changes in stimulus predictability.

    Science.gov (United States)

    Katzner, Steffen; Treue, Stefan; Busse, Laura

    2012-09-04

    One of the key features of active perception is the ability to predict critical sensory events. Humans and animals can implicitly learn statistical regularities in the timing of events and use them to improve behavioral performance. Here, we used a signal detection approach to investigate whether such improvements in performance result from changes of perceptual sensitivity or rather from adjustments of a response criterion. In a regular sequence of briefly presented stimuli, human observers performed a noise-limited motion detection task by monitoring the stimulus stream for the appearance of a designated target direction. We manipulated target predictability through the hazard rate, which specifies the likelihood that a target is about to occur, given it has not occurred so far. Analyses of response accuracy revealed that improvements in performance could be accounted for by adjustments of the response criterion; a growing hazard rate was paralleled by an increasing tendency to report the presence of a target. In contrast, the hazard rate did not affect perceptual sensitivity. Consistent with previous research, we also found that reaction time decreases as the hazard rate grows. A simple rise-to-threshold model could well describe this decrease and attribute predictability effects to threshold adjustments rather than changes in information supply. We conclude that, even under conditions of full attention and constant perceptual sensitivity, behavioral performance can be optimized by dynamically adjusting the response criterion to meet ongoing changes in the likelihood of a target.

  11. An Analysis of Unglazed Transpired Solar Collectors Based on Exergetic Performance Criteria

    OpenAIRE

    Motahar, Sadegh

    2010-01-01

    In this paper, an exergetic performance analysis of unglazed transpired collectors (UTC), as well as an exergetic optimization of a typical UTC is performed. A fuzzy multi criteria approach for evaluating green supplier's performance in green supply chain with linguistic preferences

    DEFF Research Database (Denmark)

    Shen, Lixin; Olfat, Laya; Govindan, Kannan

    2013-01-01

    Today's international business environment has forced many firms to focus on supply chain management to gain a competitive advantage. During recent years, supplier selection process in the supply chain has become a key strategic consideration. With the growing worldwide awareness of environmental...... multi criteria approach for green suppliers' evaluation. We apply fuzzy set theory to translate the subjective human perceptions into a solid crisp value. These linguistic preferences are combined through fuzzy TOPSIS to generate an overall performance score for each supplier. A numerical example...... is presented to demonstrate the effectiveness of the proposed approach....

  12. The need for performance criteria in evaluating the durability of wood products

    Science.gov (United States)

    Stan Lebow; Bessie Woodward; Patricia Lebow; Carol Clausen

    2010-01-01

    Data generated from wood-product durability evaluations can be difficult to interpret. Standard methods used to evaluate the potential long-term durability of wood products often provide little guidance on interpretation of test results. Decisions on acceptable performance for standardization and code compliance are based on the judgment of reviewers or committees....

  13. Key Performance Indicators of Public Universities Based on Quality Assessment Criteria in Thailand

    Science.gov (United States)

    Sukboonyasatit, Kritsana; Thanapaisarn, Chaiwit; Manmar, Lampang

    2011-01-01

    The research objective was to develop public universities' key performance indicators. Qualitative research and interviews were employed with each public university's senior executive and quality assessors. The sample group was selected by the office of the public sector development commission and Thailand's public universities can be separated…

  14. Designing sustainable concrete on the basis of equivalence performance: assessment criteria for safety

    NARCIS (Netherlands)

    Visser, J.H.M.; Bigaj, A.J.

    2014-01-01

    In order not to hampers innovations, the Dutch National Building Regulations (NBR), allow an alternative approval route for new building materials. It is based on the principles of equivalent performance which states that if the solution proposed can be proven to have the same level of safety,

  15. Long-term pavement performance monitoring and the revision of performance criteria for high modulus asphalt in South Africa

    CSIR Research Space (South Africa)

    Komba, Julius

    2016-09-01

    Full Text Available Enrobé à Module Élevé (EME) technology, a High Modulus Asphalt (HiMA), was originally developed in France. The technology is primarily suitable for construction of heavily trafficked routes, airports and container terminals. The key performance...

  16. Optimizing the use of the "state-of-the-art" performance criteria.

    Science.gov (United States)

    Haeckel, Rainer; Wosniok, Werner; Streichert, Thomas

    2015-05-01

    The organizers of the first EFLM Strategic Conference "Defining analytical performance goals" identified three models for defining analytical performance goals in laboratory medicine. Whereas the highest level of model 1 (outcome studies) is difficult to implement, the other levels are more or less based on subjective opinions of experts, with models 2 (based on biological variation) and 3 (defined by the state-of-the-art) being more objective. A working group of the German Society of Clinical Chemistry and Laboratory Medicine (DGKL) proposes a combination of models 2 and 3 to overcome some disadvantages inherent to both models. In the new model, the permissible imprecision is not defined as a constant proportion of biological variation but by a non-linear relationship between permissible analytical and biological variation. Furthermore, the permissible imprecision is referred to the target quantity value. The biological variation is derived from the reference interval, if appropriate, after logarithmic transformation of the reference limits.

  17. Criteria for the Collection of Useful Respirator Performance Data in the Workplace

    OpenAIRE

    Janssen, Larry; Zhuang, Ziqing; Shaffer, Ronald

    2014-01-01

    Workplace protection factors (WPFs) are intended to measure the ability of a respiratory protective device (RPD) to reduce contaminant exposure when used in the context of an effective respiratory protection program. In 1992, members of the American Industrial Hygiene Association Respiratory Protection Committee (RPC) published a review of important issues and considerations for measuring respirator performance in the workplace. The RPC recognized that respirator testing in workplaces can hav...

  18. Criteria for the collection of useful respirator performance data in the workplace.

    Science.gov (United States)

    Janssen, Larry; Zhuang, Ziqing; Shaffer, Ronald

    2014-01-01

    Workplace protection factors (WPFs) are intended to measure the ability of a respiratory protective device (RPD) to reduce contaminant exposure when used in the context of an effective respiratory protection program. In 1992, members of the American Industrial Hygiene Association Respiratory Protection Committee (RPC) published a review of important issues and considerations for measuring respirator performance in the workplace. The RPC recognized that respirator testing in workplaces can have a variety of objectives and endpoints, and that not all workplace measurements are WPFs. That paper addressed concerns in the general categories of 1) study objectives; 2) site selection; 3) subject selection and preparation; 4) sampling and analytical methods; and 5) data analysis. No specific protocol for measuring WPFs was recommended by the RPC, and attempts to reach a U.S. consensus on a WPF protocol since 1992 have not succeeded. Numerous studies have implemented the principles for WPF measurement described in the RPC paper. Modifications to the original recommendations have been made to reflect the current state of the art. This article describes what has been learned in recent years in each of the five categories identified in the 1992 discussion. Because of the wide variety of workplaces and work activities, contaminants and respiratory protective devices, a strict protocol is not appropriate for collecting WPF data. Rather, the minimum requirements for the collection and presentation of meaningful respirator performance data in the workplace are described. Understanding of these principles will permit useful RPD performance data to be generated.

  19. Multi-rate h2 tracking control with mixed continuous-discrete performance criteria

    International Nuclear Information System (INIS)

    Kahane, A.C.; Palmor, Z.J.; Mirkin, L.

    1998-01-01

    Control goals defined both in continuous and discrete time arise naturally in many sampled-data tracking control problems. The design methods found in the literature deal with each kind of those control goals separately, over-emphasizing one kind at the expense of the other. We formulate and solve these tracking control problems as an H2 optimization problem with a mixed continuous/discrete performance criterion. It is argued that the proposed setup enables tradeoff between the various control goals in a natural manner and thus leads to better tracking characteristics

  1. Review of EPA, DOE, and NRC regulations on establishing solid waste performance criteria

    International Nuclear Information System (INIS)

    Mattus, A.J.; Gilliam, T.M.; Dole, L.R.

    1988-07-01

    This report provides a comprehensive review of the regulations concerning hazardous and radioactive waste disposal that have been issued by the US Department of Energy, the US Environmental Protection Agency, and the US Nuclear Regulatory Commission. This document addresses regulations pertaining to performance and testing requirements for solid waste forms. In cases where performance and testing requirements are tied to classification of waste forms or setting of minimum standards for groundwater, these latter topics were also reviewed. This report summarizes and compares the various regulations regarding waste disposal, and to present those regulations in an easily understandable fashion. The primary uses of this document should be to become familiar with the regulations and to compare the requirements of the various agencies. Because this is a summary document, references are made to the original regulatory documents when decisions concerning testing or waste disposal are affected by the regulations concerned herein. Also new regulations and updates are continuously being issued and should be reviewed frequently to stay abreast of possible regulatory changes. 19 refs., 1 fig. 5 tabs

  2. Pilot test of ANSI draft standard N13.29 environmental dosimetry -- Performance criteria for testing

    Energy Technology Data Exchange (ETDEWEB)

    Klemic, G.; Shebell, P.; Monetti, M.; Raccah, F. [Dept. of Energy, New York, NY (United States). Environmental Measurement Lab.; Shobe, J.; Lamperti, P.; Soares, C. [National Inst. of Standards and Technology, Gaithersburg, MD (United States); Sengupta, S. [Brookhaven National Lab., Upton, NY (United States)

    1998-09-01

    American National Standards Institute Draft N13.29 describes performance tests for environmental radiation dosimetry providers. If approved it would be the first step toward applying the types of performance testing now required in personnel dosimetry to environmental radiation monitoring. The objective of this study was to pilot test the draft standard, before it undergoes final balloting, on a small group of dosimetry providers that were selected to provide a mix of facility types, thermoluminescent dosimeter designs and monitoring program applications. The first phase of the pilot test involved exposing dosimeters to laboratory photon, beta, and x-ray sources at routine and accident dose levels. In the second phase, dosimeters were subjected to ninety days of simulated environmental conditions in an environmental chamber that cycled through extremes of temperature and humidity. Two out of seven participants passed all categories of the laboratory testing phase, and all seven passed the environmental test phase. While some relatively minor deficiencies were uncovered in the course of the pilot test, the results show that draft N13.29 describes useful tests that could be appropriate for environmental dosimetry providers. An appendix to this report contains recommendations that should be addressed by the N13.29 working group before draft N13.29 is submitted for balloting.

  3. Comprehensive Self-Assessment and Upgrade Program (CSAUP) performance objectives and criteria

    Energy Technology Data Exchange (ETDEWEB)

    1990-05-01

    The US Department of Energy (DOE) has placed strong emphasis on a new way of doing business patterned on the lessons learned in the nuclear power industry after the accident at Three Mile Island Unit 2. The new way relies on strict adherence to policies and procedures, a greatly expanded training program, and much more rigor and formality in operations. Another key element is more visible oversight by upper management and auditability by DOE. Although the Chemical Technology Division (Chem Tech) has functioned in a safe manner since its beginning, the policies and methods of the past are no longer appropriate. Therefore, in accordance with these directives, Chem Tech is improving its operational performance by making a transition to greater formality in the observance of policies and procedures and a more deliberate consideration of the interrelationships between organizations at ORNL. This transition to formality is vitally important because both our staff and our facilities are changing with time. For example, some of the inventors and developers of the processes and facilities in use are now passing the torch'' to the next generation of Chem Tech staff. Our facilities have also served us well for many years, but the newest of these are now over 20 years old All have increasing needs of refurbishment and repair, and some of the older ones need to be replaced. This procedure, based on the lessons learned in the nuclear industry, will enhance Chem Tech's operational performance in some important ways, while maintaining the special factors that have allowed the Chem Tech staff to be creative and successful in the RD D activities.

  4. Physiological, physical and on-ice performance criteria for selection of elite ice hockey teams

    Directory of Open Access Journals (Sweden)

    R Roczniok

    2016-01-01

    Full Text Available The purpose of this study was to examine physiological and physical determinants of ice-hockey performance in order to assess their impact on the result during a selection for ice hockey. A total of 42 ice hockey players took part in the selection camp. At the end of the camp 20 best players were selected by team of expert coaches to the ice hockey team and created group G1, while the second group (G2 consisted of not selected players (non-successful group Evaluation of goodness of fit of the model to the data was based on the Hosmer Lemeshow test Ice hockey players selected to the team were taller 181.95±4.02 cm, had lower % body fat 13.17±3.17%, a shorter time to peak power 2.47±0.35 s , higher relative peak power 21.34±2.41 W • kg-1 and higher relative total work 305.18±28.41 J • kg-1. The results of the aerobic capacity test showed significant differences only in case of two variables. Ice hockey players in the G1 had higher VO2max 4.07±0.31 l • min-1 values than players in the G2 as well as ice hockey players in G1 showed a higher level of relative VO2max 51.75±2.99 ml • min-1 • kg-1 than athletes in G2. Ice hockey players selected to the team (G1 performed better in the 30 m Forwards Sprint 4.28±0.31 s; 6x9 Turns 12.19±0.75 s; 6x9 stops 12.79±0.49 s and Endurance test (6x30 m stops 32.01±0.80 s than players in G2. The logistic regression model showed that the best predictors of success in the recruitment process of top level ice hockey players were time to peak power, relative peak power, VO2max and 30 m sprint forwards on ice. On the basis of the constructed predictive logistic regression model it will be possible to determine the probability of success of the athletes during following the selection processes to the team.

  5. Performance Criteria for Capture and/or Immobilization Technologies - Milestone Report

    Energy Technology Data Exchange (ETDEWEB)

    Bruffey, Stephanie H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Jubin, Robert Thomas [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Spencer, Barry B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Soelberg, Nick [Idaho National Lab. (INL), Idaho Falls, ID (United States); Riley, Brian [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-02-01

    The capture and subsequent immobilization of the four regulated volatile radionuclides (3H, 14C, 85Kr, and 129I) from the off-gas streams of a used nuclear fuel (UNF) reprocessing facility has been a topic of substantial research interest for the US Department of Energy and its international colleagues. Removal of some or all of these radionuclides (e.g., based upon fuel burnup, fuel type, cooling time) from the plant effluent streams prior to discharge to the environment is required to meet regulations set forth by the US Environmental Protection Agency. Upon removal, the radionuclide, as well as associated sorbents that cannot be cost-effectively regenerated, is destined for conversion to a waste form. Research in separation and capture methodologies has included a wide range of technologies, including liquid caustic scrubbing systems, solid adsorbents, and cryogenic distillation. The studies of waste forms have been correspondingly diverse. In considering the technologies available for future development and implementation of both sorbents and waste forms, it is necessary to identify benchmark measures of performance to evaluate objectively each sorbent system or waste form.

  6. Performance characteristics and parametric optimum criteria of a Brownian micro-refrigerator in a spatially periodic temperature field

    International Nuclear Information System (INIS)

    Lin Bihong; Chen Jincan

    2009-01-01

    It is shown that a microscopic system consisting of Brownian particles moving in a spatially asymmetric but periodic potential (ratchet) and contacting with the alternating hot and cold reservoirs along space coordinate and an external force applying on the particles may work as a refrigerator. In order to clarify the underlying physical pictures of the system, the heat flows via both the potential energy and the kinetic energy of the particles are considered simultaneously. Based on an Arrhenius' factor describing the forward and backward particle currents, expressions for some important performance parameters of the refrigerator, such as the coefficient of performance, cooling rate and power input, are derived analytically. The maximum coefficient of performance and cooling rate are numerically calculated for some given parameters. The influence of the main parameters such as the external force, barrier height of the potential, asymmetry of the potential and temperature ratio of the heat reservoirs on the performance of the Brownian refrigerator is discussed. The optimum criteria of some characteristic parameters are given. It is found that the Brownian refrigerator may be controlled to operate in different regions through the choice of several parameters

  7. Microwave induced plasma for solid fuels and waste processing: A review on affecting factors and performance criteria.

    Science.gov (United States)

    Ho, Guan Sem; Faizal, Hasan Mohd; Ani, Farid Nasir

    2017-11-01

    High temperature thermal plasma has a major drawback which consumes high energy. Therefore, non-thermal plasma which uses comparatively lower energy, for instance, microwave plasma is more attractive to be applied in gasification process. Microwave-induced plasma gasification also carries the advantages in terms of simplicity, compactness, lightweight, uniform heating and the ability to operate under atmospheric pressure that gains attention from researchers. The present paper synthesizes the current knowledge available for microwave plasma gasification on solid fuels and waste, specifically on affecting parameters and their performance. The review starts with a brief outline on microwave plasma setup in general, and followed by the effect of various operating parameters on resulting output. Operating parameters including fuel characteristics, fuel injection position, microwave power, addition of steam, oxygen/fuel ratio and plasma working gas flow rate are discussed along with several performance criteria such as resulting syngas composition, efficiency, carbon conversion, and hydrogen production rate. Based on the present review, fuel retention time is found to be the key parameter that influences the gasification performance. Therefore, emphasis on retention time is necessary in order to improve the performance of microwave plasma gasification of solid fuels and wastes. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Determination of performance criteria of safety systems in a nuclear power plant via simulated annealing optimization method

    International Nuclear Information System (INIS)

    Jung, Woo Sik

    1993-02-01

    This study presents and efficient methodology that derives design alternatives and performance criteria of safety functions/systems in commercial nuclear power plants. Determination of design alternatives and intermediate-level performance criteria is posed as a reliability allocation problem. The reliability allocation is performed for determination of reliabilities of safety functions/systems from top-level performance criteria. The reliability allocation is a very difficult multi objective optimization problem (MOP) as well as a global optimization problem with many local minima. The weighted Chebyshev norm (WCN) approach in combination with an improved Metropolis algorithm of simulated annealing is developed and applied to the reliability allocation problem. The hierarchy of probabilistic safety criteria (PSC) may consist of three levels, which ranges from the overall top level (e.g., core damage frequency, acute fatality and latent cancer fatality) through the interlnediate level (e.g., unavailiability of safety system/function) to the low level (e.g., unavailability of components, component specifications or human error). In order to determine design alternatives of safety functions/systems and the intermediate-level PSC, the reliability allocation is performed from the top-level PSC. The intermediated level corresponds to an objective space and the top level is related to a risk space. The reliability allocation is performed by means of a concept of two-tier noninferior solutions in the objective and risk spaces within the top-level PSC. In this study, two kinds of towtier noninferior solutions are defined: intolerable intermediate-level PSC and desirable design alternatives of safety functions/systems that are determined from Sets 1 and 2, respectively. Set 1 is obtained by maximizing simultaneously not only safety function/system unavailabilities but also risks. Set 1 reflects safety function/system unavailabilities in the worst case. Hence, the

  9. The Stringent Response Induced by Phosphate Limitation Promotes Purine Salvage in Agrobacterium fabrum.

    Science.gov (United States)

    Sivapragasam, Smitha; Deochand, Dinesh K; Meariman, Jacob K; Grove, Anne

    2017-10-31

    Agrobacterium fabrum induces tumor growth in susceptible plant species. The upregulation of virulence genes that occurs when the bacterium senses plant-derived compounds is enhanced by acidic pH and limiting inorganic phosphate. Nutrient starvation may also trigger the stringent response, and purine salvage is among the pathways expected to be favored under such conditions. We show here that phosphate limitation induces the stringent response, as evidenced by production of (p)ppGpp, and that the xdhCSML operon encoding the purine salvage enzyme xanthine dehydrogenase is upregulated ∼15-fold. The xdhCSML operon is under control of the TetR family transcription factor XdhR; direct binding of ppGpp to XdhR attenuates DNA binding, and the enhanced xdhCSML expression correlates with increased cellular levels of (p)ppGpp. Xanthine dehydrogenase may also divert purines away from salvage pathways to form urate, the ligand for the transcription factor PecS, which in the plant pathogen Dickeya dadantii is a key regulator of virulence gene expression. However, urate levels remain low under conditions that produce increased levels of xdhCSML expression, and neither acidic pH nor limiting phosphate results in induction of genes under control of PecS. Instead, expression of such genes is induced only by externally supplemented urate. Taken together, our data indicate that purine salvage is favored during the stringent response induced by phosphate starvation, suggesting that control of this pathway may constitute a novel approach to modulating virulence. Because bacterial purine catabolism appears to be unaffected, as evidenced by the absence of urate accumulation, we further propose that the PecS regulon is induced by only host-derived urate.

  10. KETERKAITAN KATEGORI KEPEMIMPINAN DENGAN ENAM KATEGORI LAINNYA DALAM MALCOLM BALDRIGE CRITERIA FOR PERFORMANCE EXCELLENCE (MBCFPE PADA BADAN USAHA MILIK NEGARA

    Directory of Open Access Journals (Sweden)

    Rudjito Rudjito

    2011-08-01

    Full Text Available Normal 0 false false false MicrosoftInternetExplorer4 Some State Own Enterprises (SOEs have measured their performance based on Malcolm Baldrige Criteria for Performance Excellence method yearly since 2005 and participated in Indonesia Quality Award (IQA to recognize their performances. The MBCfPE method measures company performance based on seven criterion categories, which Leadership as the first category is stated in the method that must be visionary, motivator and as the driver to lead people and entire organization to achieve performance excellence. The purposes of this study is to analyze the interrelatation of Leadership as first category to category second up to category seventh of MBCfPE.Convenience and purposive (judgmental sampling techniques are used to choose twelve SOEs, which consist of two groups of six SOEs: “Good Performance” and “Below Good Performance”. Two hundred seventy two respondents consist of SOEs’ CEO, management and employees who understand MBCfPE method have participated in this study which selected by judgmental sampling technique. Reseacher used Rank Spearman and Discriminant anlysis for analyzing the interrelation of leadership category to category second up to seventh of MBCfPE. According to rank-spearman correlation analysis results, in overall, most of variables X (areas to address of Laedership category, have relation with variables Y (areas to address of category second up category seventh of MBCfPE, except for variable X4 (Legal and ethical behavior and variable X5 (Societal Responsibility and Support of key communities to variable Y1 (Strategy development process. From Discriminant analysis, it can be concluded that Communication and Company Performance is variable that discriminate between SOEs “Good Performance” and SOEs “Below Good Performance”.

  11. Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (pppGpp synthase

    Directory of Open Access Journals (Sweden)

    Kalinowski Jörn

    2006-09-01

    Full Text Available Background The stringent response is the initial reaction of microorganisms to nutritional stress. During stringent response the small nucleotides (pppGpp act as global regulators and reprogram bacterial transcription. In this work, the genetic network controlled by the stringent response was characterized in the amino acid-producing Corynebacterium glutamicum. Results The transcriptome of a C. glutamicum rel gene deletion mutant, unable to synthesize (pppGpp and to induce the stringent response, was compared with that of its rel-proficient parent strain by microarray analysis. A total of 357 genes were found to be transcribed differentially in the rel-deficient mutant strain. In a second experiment, the stringent response was induced by addition of DL-serine hydroxamate (SHX in early exponential growth phase. The time point of the maximal effect on transcription was determined by real-time RT-PCR using the histidine and serine biosynthetic genes. Transcription of all of these genes reached a maximum at 10 minutes after SHX addition. Microarray experiments were performed comparing the transcriptomes of SHX-induced cultures of the rel-proficient strain and the rel mutant. The differentially expressed genes were grouped into three classes. Class A comprises genes which are differentially regulated only in the presence of an intact rel gene. This class includes the non-essential sigma factor gene sigB which was upregulated and a large number of genes involved in nitrogen metabolism which were downregulated. Class B comprises genes which were differentially regulated in response to SHX in both strains, independent of the rel gene. A large number of genes encoding ribosomal proteins fall into this class, all being downregulated. Class C comprises genes which were differentially regulated in response to SHX only in the rel mutant. This class includes genes encoding putative stress proteins and global transcriptional regulators that might be

  12. Performance of seven criteria to assess CA125 increments among ovarian cancer patients monitored during first-line chemotherapy and the post-therapy follow-up period

    DEFF Research Database (Denmark)

    Abu Hassan, Suher O; Nielsen, Dorte L; Tuxen, Malgorzata K

    2017-01-01

    AIM: To investigate seven CA125 criteria to monitor progressive ovarian cancer among patients with stage IC-IV disease. MATERIALS & METHODS: Four criteria were used to asses CA125 increments starting from concentrations ≥35 U/ml and three criteria to asses increments starting from concentrations...... CA125 monitoring. The performances of the CA125 criteria were similar with sensitivities of 30-55%, negative predictive values of 28-46%, positive predictive values of 90-100% and median lead times of 26-87 days. CONCLUSION: The criteria...... showed low sensitivity and inability to exclude progressive ovarian cancer. The study suggests that CA125 information cannot stand alone but should be considered used in conjunction with other investigative procedures....

  13. Accommodating those Most at Risk. Responding to a Mismatch in Programme Selection Criteria and Foundation Biology Performance

    Science.gov (United States)

    Kirby, Nicola F.; Dempster, Edith R.

    2015-12-01

    In South Africa, foundation programmes are a well-established alternative access route to tertiary science study for educationally disadvantaged students. Student access to, and performance in, one such foundation programme has been researched by the authors seeking opportunities to improve student retention. The biology module in particular has been recognised to place students at risk of failing the foundation programme, thereby reducing throughput into mainstream science programmes. This study uses decision tree analysis to provide a detailed description of foundation biology student performance so that points of weakness and opportunities for remedial action may be pinpointed. While students' alternative-entry selection scores have previously been found to most effectively account for performance in the programme as a whole, no similar positive relationship was identified for any subgroup of students in the foundation biology module. Conversely, academic language proficiency in the medium of instruction (English), formerly found to play no role in overall student performance, was revealed as primary in explaining achievement in foundation biology, most adversely affecting students rendered particularly vulnerable by an additional academic and/or socio-economic disadvantage. A pass in the stand-alone foundation academic literacy module did not necessarily correspond to a pass in biology. Compromised by educational disadvantage, compounded by a mismatch in programme selection criteria and inadequate academic literacy support, discipline-specific, fundamental literacy development in the biology curriculum is proposed to enable students towards epistemic access in the module. Pending this intervention, formal access to mainstream study is unlikely for the foundation students most at risk of failure.

  14. Performance characteristics of seven bilevel mechanical ventilators in pressure-support mode with different cycling criteria: a comparative bench study.

    Science.gov (United States)

    Chen, Yuqing; Cheng, Kewen; Zhou, Xin

    2015-01-26

    Pressure support ventilation from a bilevel device is a standard technique for non-invasive home ventilation. A bench study was designed to compare the performance and patient-ventilator synchronization of 7 bilevel ventilators, in the presence of system leaks. Ventilators were connected to a Hans Rudolph Series 1101 lung simulator (compliance, 50 mL/cmH2O; expiratory resistance, 20 cmH2O/L/s; respiratory rate, 15 breaths/min; inspiratory time, 1.0 s). All ventilators were set at 15 cmH2O pressure support and 5 cmH2O positive end-expiratory pressure. Tests were conducted at 2 system leaks (12-15 and 25-28 L/min). The performance characteristics and patient-ventilator asynchrony were assessed, including flow, airway pressure, time, and workload. The Breas Vivo30 could not synchronize with the simulator (frequent auto-triggering) at a leak of 25-28 L/min, but provided stable assisted ventilation when the leak was 12-15 L/min. Missed efforts and back-up ventilation occurred for the Weinmann VENTImotion and Airox Smartair Plus, requiring adjustment of trigger effort. All ventilators had a short trigger delay time (ventilators, possibly due to software algorithm differences. Adjusting the cycling criteria settings can alter the shape of the inspiratory phase and peak expiratory flow, and improve patient-ventilator synchrony.

  15. Radiation protection - Performance criteria for laboratories performing cytogenetic triage for assessment of mass casualties in radiological or nuclear emergencies - General principles and application to dicentric assay

    International Nuclear Information System (INIS)

    2008-01-01

    The potential for nuclear and radiological emergencies involving mass casualties from accidental or malicious acts or terrorism requires generic procedures for emergency dose assessment to help the development of medical response capabilities. A mass-casualties incident is defined here as an event that exceeds the local medical resources. Biological dosimetry, based on cytogenetic analysis using the dicentric assay, typically applied for accidental dose assessment, has been defined in ISO 19238. Cytogenetic triage is the use of chromosome damage to evaluate and assess approximately and rapidly radiation doses received by individuals in order to supplement the clinical categorization of casualties. This International Standard focuses on the use of the dicentric assay for rapid cytogenetic triage involving mass-casualty incidents. The primary purpose of this International Standard is to provide a guideline to all laboratories in order to perform the dicentric-bioassay - cytogenetic triage for dose assessment using documented and validated procedures. Secondly, it can facilitate the application of cytogenetic biodosimetry networks to permit comparison of results obtained in different laboratories. Finally, it is expected that laboratories newly commissioned to carry out the cytogenetic triage conform to this International Standard in order to perform the triage reproducibly and accurately. This International Standard is written in the form of procedures to adopt for dicentric-bioassay - cytogenetic triage biological dosimetry for overexposures involving mass radiological casualties. The criteria required for such measurements usually depend on the application of the results: medical management when appropriate, radiation-protection management, record keeping and medical/legal requirements. For example, selected cases can be analysed to produce a more accurate evaluation of high partial-body exposure; secondly, doses can be estimated for persons exposed below the

  16. Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

    DEFF Research Database (Denmark)

    Petri, Michelle; Orbai, Ana-Maria; Alarcón, Graciela S

    2012-01-01

    The Systemic Lupus International Collaborating Clinics (SLICC) group revised and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) classification criteria in order to improve clinical relevance, meet stringent methodology requirements, and incorporate new...

  17. Performance of the 2012 Systemic Lupus International Collaborating Clinics classification criteria versus the 1997 American College of Rheumatology classification criteria in adult and juvenile systemic lupus erythematosus. A systematic review and meta-analysis.

    Science.gov (United States)

    Hartman, Esther A R; van Royen-Kerkhof, Annet; Jacobs, Johannes W G; Welsing, Paco M J; Fritsch-Stork, Ruth D E

    2018-03-01

    To evaluate the performance in classifying systemic lupus erythematosus by the 2012 Systemic Lupus International Collaborating Clinics criteria (SLICC'12), versus the revised American College of Rheumatology criteria from 1997 (ACR'97) in adult and juvenile SLE patients. A systematic literature search was conducted in PubMed and Embase for studies comparing SLICC'12 and ACR'97 with clinical diagnosis. A meta-analysis was performed to estimate the sensitivity and specificity of SLICC'12 and ACR'97. To assess classification earlier in the disease by either set, sensitivity and specificity were compared for patients with disease duration <5years. Sensitivity and specificity of individual criteria items were also assessed. In adult SLE (nine studies: 5236 patients, 1313 controls), SLICC'12 has higher sensitivity (94.6% vs. 89.6%) and similar specificity (95.5% vs. 98.1%) compared to ACR'97. For juvenile SLE (four studies: 568 patients, 339 controls), SLICC'12 demonstrates higher sensitivity (99.9% vs. 84.3%) than ACR'97, but much lower specificity (82.0% vs. 94.1%). SLICC'12 classifies juvenile SLE patients earlier in disease course. Individual items contributing to diagnostic accuracy are low complement, anti-ds DNA and acute cutaneous lupus in SLICC'12, and the immunologic and hematologic disorder in ACR'97. Based on sensitivity and specificity SLICC'12 is best for adult SLE. Following the view that higher specificity, i.e. avoidance of false positives, is preferable, ACR'97 is best for juvenile SLE even if associated with lower sensitivity. Our results on the contribution of the individual items of SLICC'12 and ACR´97 may be of value in future efforts to update classification criteria. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  18. Air Quality and Health Benefits of China's Recent Stringent Environmental Policy

    Science.gov (United States)

    Zheng, Y.; Xue, T.; Zhang, Q.; Geng, G.; He, K.

    2016-12-01

    Aggressive emission control measures were taken by China's central and local governments after the promulgation of the "Air Pollution Prevention and Control Action Plan" in 2013. We evaluated the air quality and health benefits of this ever most stringent air pollution control policy during 2013-2015 by utilizing a two-stage data fusion model and newly-developed cause-specific integrated exposure-response functions (IER) developed for the Global Burden of Disease (GBD). The two-stage data fusion model predicts spatiotemporal continuous PM2.5 (particulate matter with aerodynamic diameter less than 2.5 µm) concentrations by integrating satellite-derived aerosol optical depth (AOD) measurements, PM2.5 concentrations from measurement and air quality model, and other ancillary information. During the years of analysis, PM2.5 concentration dropped significantly on national average and over heavily polluted regions as identified by Mann-Kendall analysis. The national PM2.5-attributable mortality decreased by 72.8 (95% CI: 59.4, 85.2) thousand (6%) from 1.23 (95% CI: 1.06, 1.39) million in 2013 to 1.15 (95% CI: 0.98, 1.31) million in 2015 due to considerable reduction (i.e. 18%) of population-weighted PM2.5 from 61.4 to 50.5 µg/m3. Meteorological variations between 2013 and 2015 were estimated to raise the PM2.5 levels by 0.24 µg/m3 and national mortality by 2.1 (95% CI: 1.6, 2.6) thousand through sensitivity tests, which implies the dominant role of anthropogenic impacts on PM2.5 abatement and attributable mortality reduction. Our study affirms the effectiveness of China's recent air quality policy, however, due to the possible supralinear shape of C-R functions, health benefits induced by air quality improvement in these years are limited. We therefore appeal for continuous implementation of current policies and further stringent measures from both air quality improvement and public health protection perspectives.

  19. GIS-based multicriteria municipal solid waste landfill suitability analysis: a review of the methodologies performed and criteria implemented.

    Science.gov (United States)

    Demesouka, O E; Vavatsikos, A P; Anagnostopoulos, K P

    2014-04-01

    Multicriteria spatial decision support systems (MC-SDSS) have emerged as an integration of the geographical information systems (GIS) and multiple criteria decision analysis (MCDA) methods. GIS-based MCDA allows the incorporation of conflicting objectives and decision maker (DM) preferences into spatial decision models. During recent decades, a variety of research articles have been published regarding the implementation of methods and/or tools in a variety of real-world case studies. The article discusses, in detail, the criteria and methods that are implemented in GIS-based landfill siting suitability analysis and especially the exclusionary and non-exclusionary criteria that can be considered when selecting sites for municipal solid waste (MSW) landfills. This paper reviews 36 seminal articles in which the evaluation of candidate landfill sites is conducted using MCDA methods. After a brief description of the main components of a MC-SDSS and the applied decision rules, the review focuses on the criteria incorporated into the decision models. The review provides a comprehensive guide to the landfill siting analysis criteria, providing details regarding the utilization methods, their decision or exclusionary nature and their monotonicity.

  20. A proposed framework for establishing integrated cost and performance criteria for environmental technologies. A summary report to the U.S. Department of Energy

    International Nuclear Information System (INIS)

    1994-05-01

    Through an Interagency Agreement between the US Environmental Protection Agency (EPA) and the US Department of Energy (DOE), EPA directed a project to establish a suite of standard cost and performance criteria to guide the evaluation of environmental cleanup technologies for DOE sites. Ideally, these criteria would be ''generic'' in that they could be used as a basis for evaluating any cleanup technology for any DOE site. To be most useful, however, these criteria would also reflect the interests of diverse decisionmakers who influence DOE technology evaluation. The project was conducted by the National Environmental Technology Applications Center (NETAC), a nonprofit organization specializing in the development and commercialization of new and innovative environmental technologies for national and international markets. To accomplish the project objective, NETAC (1) developed a data gathering questionnaire, (2) interviewed government and industry decisionmakers, (3) identified previous criteria development efforts, (4) conducted a workshop, (5) evaluated workshop discussions, and (6) applied its five years' experience in commercializing environmental technologies to analyze project findings. The project resulted in the development of a unique and comprehensive resource or tool to enhance communication among decisionmakers. This resource, a ''Proposed Framework for Establishing Integrated Cost and Performance Criteria for Evaluating Environmental Cleanup Technologies for DOE Sites,'' offers decisionmakers a first-time comprehensive assessment of major technology evaluation issues by a decisionmaker group

  1. Alignment of University Information Technology Resources with the Malcolm Baldrige Results Criteria for Performance Excellence in Education: A Balanced Scorecard Approach

    Science.gov (United States)

    Beard, Deborah F.; Humphrey, Roberta L.

    2014-01-01

    The authors suggest using a balanced scorecard (BSC) approach to evaluate information technology (IT) resources in higher education institutions. The BSC approach illustrated is based on the performance criteria of the Malcolm Baldrige National Quality Award in Education. This article suggests areas of potential impact of IT on BSC measures in…

  2. Does dishonesty really invite third-party punishment? Results of a more stringent test.

    Science.gov (United States)

    Konishi, Naoki; Ohtsubo, Yohsuke

    2015-05-01

    Many experiments have demonstrated that people are willing to incur cost to punish norm violators even when they are not directly harmed by the violation. Such altruistic third-party punishment is often considered an evolutionary underpinning of large-scale human cooperation. However, some scholars argue that previously demonstrated altruistic third-party punishment against fairness-norm violations may be an experimental artefact. For example, envy-driven retaliatory behaviour (i.e. spite) towards better-off unfair game players may be misidentified as altruistic punishment. Indeed, a recent experiment demonstrated that participants ceased to inflict third-party punishment against an unfair player once a series of key methodological problems were systematically controlled for. Noticing that a previous finding regarding apparently altruistic third-party punishment against honesty-norm violations may have been subject to methodological issues, we used a different and what we consider to be a more sound design to evaluate these findings. Third-party punishment against dishonest players withstood this more stringent test. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  3. Emission reductions in transition economies: A result of output contraction or more stringent environmental policy?

    Energy Technology Data Exchange (ETDEWEB)

    Zugravu, N.; Millock, K. [University Paris 1 Pantheon-Sorbonne (France); Duchene, G. [University Paris 12, Creteil (France)

    2007-07-01

    Countries in Central and Eastern Europe significantly reduced their CO{sub 2} emissions between 1996 and 2001. Was this emission reduction just the fortuitous result of the major economic transformation undergone by those countries in the transition away from a centralized plan economy? Or is the emission reduction rather a result of more stringent environmental policy? The objective of the article is to answer this question through a model of the relation between environmental quality and enforcement, on the one hand, and environmental quality and economic growth, on the other hand. The authors develop structural equations for the demand (emissions) and supply (environmental stringency) of pollution. The supply equation takes into account the institutional quality of the country (control of corruption and political stability) as well as consumer preferences for environmental quality, as proxied by per capita revenue and unemployment. The system is estimated by three stage least squares on a sample of three groups of countries for comparative analysis: Central and Eastern European countries, Western European countries, and emerging economies. The results indicate that, all else equal, the scale effect on its own would have increased industrial CO{sub 2} emissions in the Central and Eastern European countries in the sample by 44.6% between 1996 and 2001. The composition effect accounted for a corresponding reduction in emissions by 16%. The technique effect had the largest marginal impact, corresponding to a 37.4% reduction in emissions.

  4. The Stringent Response Promotes Antibiotic Resistance Dissemination by Regulating Integron Integrase Expression in Biofilms

    Directory of Open Access Journals (Sweden)

    Emilie Strugeon

    2016-08-01

    Full Text Available Class 1 integrons are genetic systems that enable bacteria to capture and express gene cassettes. These integrons, when isolated in clinical contexts, most often carry antibiotic resistance gene cassettes. They play a major role in the dissemination of antibiotic resistance among Gram-negative bacteria. The key element of integrons is the integrase, which allows gene cassettes to be acquired and shuffled. Planktonic culture experiments have shown that integrase expression is regulated by the bacterial SOS response. In natural settings, however, bacteria generally live in biofilms, which are characterized by strong antibiotic resilience and by increased expression of stress-related genes. Here, we report that under biofilm conditions, the stringent response, which is induced upon starvation, (i increases basal integrase and SOS regulon gene expression via induction of the SOS response and (ii exerts biofilm-specific regulation of the integrase via the Lon protease. This indicates that biofilm environments favor integron-mediated acquisition of antibiotic resistance and other adaptive functions encoded by gene cassettes.

  5. Diagnostic performance of Baveno IV criteria in cirrhotic patients with upper gastrointestinal bleeding: analysis of the F7 liver-1288 study population.

    Science.gov (United States)

    Thabut, D; D'Amico, G; Tan, P; De Franchis, R; Fabricius, S; Lebrec, D; Bosch, J; Bendtsen, F

    2010-12-01

    The definition of failure to control bleeding agreed upon at the Baveno IV consensus meeting, included the Adjusted Blood Requirement Index [ABRI: number of blood units/(final-initial hematocrit+0.01)]. ABRI ≥0.75 denotes failure. However, timing for hematocrit measurements was not defined. The aims of this study were: (1) to assess the Baveno IV criteria performance to classify treatment success or failure to control bleeding at 5 days, (2) to determine the appropriate timing for hematocrit. Two hundred and forty-two cirrhotic patients with gastrointestinal bleeding were independently classified by three clinical experts according to the Baveno IV criteria, by analysis of the database of a randomized trial. ABRI was calculated by using the closest hematocrit to the 5 day time point from the first trial product administration (ABRI-1) or after the latest transfusion within the 5-day period (ABRI-2). The gold standard for success/failure for 5-day control of bleeding was the clinical judgment of the three independent observers based on all the clinical and follow-up data. Inter-observer agreement for the final outcome assessment was 0.82 and a final consensus was obtained in 236/242 patients. Inter-observer agreement on patient classification with Baveno IV criteria was 0.70 with ABRI-1 and 0.84 with ABRI-2. c-statistics for correct patients classification were 0.86 for ABRI-1, 0.84 for ABRI-2, and 0.88 for Baveno IV criteria without ABRI. ABRI-1 caused misclassification of 27 patients and ABRI-2 of 39. Baveno IV criteria are accurate to assess outcome of patients with variceal bleeding. There is a substantial observer variability linked to timing of hematocrits for ABRI calculation. With the current definition ABRI does not add to the performance of the other criteria. Copyright © 2010 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

  6. Adaptation to fluctuating temperatures in an RNA virus is driven by the most stringent selective pressure.

    Directory of Open Access Journals (Sweden)

    María Arribas

    Full Text Available The frequency of change in the selective pressures is one of the main factors driving evolution. It is generally accepted that constant environments select specialist organisms whereas changing environments favour generalists. The particular outcome achieved in either case also depends on the relative strength of the selective pressures and on the fitness costs of mutations across environments. RNA viruses are characterized by their high genetic diversity, which provides fast adaptation to environmental changes and helps them evade most antiviral treatments. Therefore, the study of the adaptive possibilities of RNA viruses is highly relevant for both basic and applied research. In this study we have evolved an RNA virus, the bacteriophage Qβ, under three different temperatures that either were kept constant or alternated periodically. The populations obtained were analyzed at the phenotypic and the genotypic level to characterize the evolutionary process followed by the virus in each case and the amount of convergent genetic changes attained. Finally, we also investigated the influence of the pre-existent genetic diversity on adaptation to high temperature. The main conclusions that arise from our results are: i under periodically changing temperature conditions, evolution of bacteriophage Qβ is driven by the most stringent selective pressure, ii there is a high degree of evolutionary convergence between replicated populations and also among populations evolved at different temperatures, iii there are mutations specific of a particular condition, and iv adaptation to high temperatures in populations differing in their pre-existent genetic diversity takes place through the selection of a common set of mutations.

  7. The rapidly evolving centromere-specific histone has stringent functional requirements in Arabidopsis thaliana.

    Science.gov (United States)

    Ravi, Maruthachalam; Kwong, Pak N; Menorca, Ron M G; Valencia, Joel T; Ramahi, Joseph S; Stewart, Jodi L; Tran, Robert K; Sundaresan, Venkatesan; Comai, Luca; Chan, Simon W-L

    2010-10-01

    Centromeres control chromosome inheritance in eukaryotes, yet their DNA structure and primary sequence are hypervariable. Most animals and plants have megabases of tandem repeats at their centromeres, unlike yeast with unique centromere sequences. Centromere function requires the centromere-specific histone CENH3 (CENP-A in human), which replaces histone H3 in centromeric nucleosomes. CENH3 evolves rapidly, particularly in its N-terminal tail domain. A portion of the CENH3 histone-fold domain, the CENP-A targeting domain (CATD), has been previously shown to confer kinetochore localization and centromere function when swapped into human H3. Furthermore, CENP-A in human cells can be functionally replaced by CENH3 from distantly related organisms including Saccharomyces cerevisiae. We have used cenh3-1 (a null mutant in Arabidopsis thaliana) to replace endogenous CENH3 with GFP-tagged variants. A H3.3 tail domain-CENH3 histone-fold domain chimera rescued viability of cenh3-1, but CENH3's lacking a tail domain were nonfunctional. In contrast to human results, H3 containing the A. thaliana CATD cannot complement cenh3-1. GFP-CENH3 from the sister species A. arenosa functionally replaces A. thaliana CENH3. GFP-CENH3 from the close relative Brassica rapa was targeted to centromeres, but did not complement cenh3-1, indicating that kinetochore localization and centromere function can be uncoupled. We conclude that CENH3 function in A. thaliana, an organism with large tandem repeat centromeres, has stringent requirements for functional complementation in mitosis.

  8. A conceptual framework for a sports knee injury performance profile (SKIPP) and return to activity criteria (RTAC)

    OpenAIRE

    Logerstedt, David; Arundale, Amelia; Lynch, Andrew; Snyder-Mackler, Lynn

    2015-01-01

    ABSTRACTInjuries to the knee, including intra-articular fractures, ligamentous ruptures, and meniscal and articular cartilage lesions, are commonplace within sports. Despite advancements in surgical techniques and enhanced rehabilitation, athletes returning to cutting, pivoting, and jumping sports after a knee injury are at greater risk of sustaining a second injury. The clinical utility of objective criteria presents a decision-making challenge to ensure athletes are fully rehabilitated and ...

  9. Ability of admissions criteria to predict early academic performance among students of health science colleges at King Saud University, Saudi Arabia.

    Science.gov (United States)

    Alhadlaq, Adel M; Alshammari, Osama F; Alsager, Saleh M; Neel, Khalid A Fouda; Mohamed, Ashry G

    2015-06-01

    The aim of this study was to evaluate the ability of admissions criteria at King Saud University (KSU), Riyadh, Saudi Arabia, to predict students' early academic performance at three health science colleges (medicine, dentistry, and pharmacy). A retrospective cohort study was conducted with data from the records of students enrolled in the three colleges from the 2008-09 to 2010-11 academic years. The admissions criteria-high school grade average (HSGA), aptitude test (APT) score, and achievement test (ACT) score-were the independent variables. The dependent variable was the average of students' first- and second-year grade point average (GPA). The results showed that the ACT was a better predictor of the students' early academic performance than the HSGA (β=0.368, β=0.254, respectively). No significant relationship was found between the APT and students' early academic performance (β=-0.019, p>0.01). The ACT was most predictive for pharmacy students (β=0.405), followed by dental students (β =0.392) and medical students (β=0.195). Overall, the current admissions criteria explained only 25.5% of the variance in the students' early academic performance. While the ACT and HSGA were found to be predictive of students' early academic performance in health colleges at KSU, the APT was not a strong predictor. Since the combined current admissions criteria for the health science colleges at KSU were weak predictors of the variance in early academic performance, it may be necessary to consider noncognitive evaluation methods during the admission process.

  10. Uncertainties in the Forecasted Performance of Sediment Diversions Associated with Differences Between "Optimized" Diversion Design Criteria and the Natural Crevasse-Splay Sub-Delta Life-Cycle

    Science.gov (United States)

    Brown, G.

    2017-12-01

    Sediment diversions have been proposed as a crucial component of the restoration of Coastal Louisiana. They are generally characterized as a means of creating land by mimicking natural crevasse-splay sub-delta processes. However, the criteria that are often promoted to optimize the performance of these diversions (i.e. large, sand-rich diversions into existing, degraded wetlands) are at odds with the natural processes that govern the development of crevasse-splay sub-deltas (typically sand-lean or sand-neutral diversions into open water). This is due in large part to the fact that these optimization criteria have been developed in the absence of consideration for the natural constraints associated with fundamental hydraulics: specifically, the conservation of mechanical energy. Although the implementation of the aforementioned optimization criteria have the potential to greatly increase the land-building capacity of a given diversion, the concomitant widespread inundation of the existing wetlands (an unavoidable consequence of diverting into a shallow, vegetated embayment), and the resultant stresses on existing wetland vegetation, have the potential to dramatically accelerate the loss of these existing wetlands. Hence, there are inherent uncertainties in the forecasted performance of sediment diversions that are designed according to the criteria mentioned above. This talk details the reasons for these uncertainties, using analytic and numerical model results, together with evidence from field observations and experiments. The likelihood that, in the foreseeable future, these uncertainties can be reduced, or even rationally bounded, is discussed.

  11. Stringently Defined Otitis Prone Children Demonstrate Deficient Naturally Induced Mucosal Antibody Response to Moraxella catarrhalis Proteins

    Directory of Open Access Journals (Sweden)

    Dabin Ren

    2017-08-01

    Full Text Available Moraxella catarrhalis (Mcat is a prominent mucosal pathogen causing acute otitis media (AOM. We studied Mcat nasopharyngeal (NP colonization, AOM frequency and mucosal antibody responses to four vaccine candidate Mcat proteins: outer membrane protein (OMP CD, oligopeptide permease (Opp A, hemagglutinin (Hag, and Pilin A clade 2 (PilA2 from stringently defined otitis prone (sOP children, who experience the greatest burden of disease, compared to non-otitis prone (NOP children. sOP children had higher NP colonization of Mcat (30 vs. 22%, P = 0.0003 and Mcat-caused AOM rates (49 vs. 24%, P < 0.0001 than NOP children. Natural acquisition of mucosal antibodies to Mcat proteins OMP CD (IgG, P < 0.0001, OppA (IgG, P = 0.018, Hag (IgG and IgA, both P < 0.0001, and PilA2 (IgA, P < 0.0001 was lower in sOP than NOP children. Higher levels of mucosal IgG to Hag (P = 0.039 and PilA2 (P = 0.0076, and IgA to OMP CD (P = 0.010, OppA (P = 0.030, and PilA2 (P = 0.043 were associated with lower carriage of Mcat in NOP but not sOP children. Higher levels of mucosal IgG to OMP CD (P = 0.0070 and Hag (P = 0.0003, and IgA to Hag (P = 0.0067 at asymptomatic colonization than those at onset of AOM were associated with significantly lower rate of Mcat NP colonization progressing to AOM in NOP compared to sOP children (3 vs. 26%, P < 0.0001. In conclusion, sOP children had a diminished mucosal antibody response to Mcat proteins, which was associated with higher frequencies of asymptomatic NP colonization and NP colonization progressing to Mcat-caused AOM. Enhancing Mcat antigen-specific mucosal immune responses to levels higher than achieved by natural exposure will be necessary to prevent AOM in sOP children.

  12. Role of the Stringent Stress Response in the Antibiotic Resistance Phenotype of Methicillin-Resistant Staphylococcus aureus.

    Science.gov (United States)

    Aedo, Sandra; Tomasz, Alexander

    2016-04-01

    Resistance to beta-lactam antibiotics in methicillin-resistantStaphylococcus aureus(MRSA) requires the presence of an acquired genetic determinant,mecAormecC, which encode penicillin-binding protein PBP2A or PBP2A', respectively. Although all MRSA strains share a mechanism of resistance, the phenotypic expression of beta-lactam resistance shows considerable strain-to-strain variation. The stringent stress response, a stress response that results from nutrient limitation, was shown to play a key role in determining the resistance level of an MRSA strain. In the present study, we validated the impact of the stringent stress response on transcription and translation ofmecAin the MRSA clinical isolate strain N315, which also carries known regulatory genes (mecI/mecR1/mecR2andblaI/blaR1) formecAtranscription. We showed that the impact of the stringent stress response on the resistance level may be restricted to beta-lactam resistance based on a "foreign" determinant such asmecA, as opposed to resistance based on mutations in the nativeS. aureusdeterminantpbpB(encoding PBP2). Our observations demonstrate that high-level resistance mediated by the stringent stress response follows the current model of beta-lactam resistance in which the native PBP2 protein is also essential for expression of the resistance phenotype. We also show that theStaphylococcus sciuri pbpDgene (also calledmecAI), the putative evolutionary precursor ofmecA, confers oxacillin resistance in anS. aureusstrain, generating a heterogeneous phenotype that can be converted to high and homogenous resistance by induction of the stringent stress response in the bacteria. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  13. Diagnostic performance of Baveno IV criteria in cirrhotic patients with upper gastrointestinal bleeding: analysis of the F7 liver-1288 study population

    DEFF Research Database (Denmark)

    Thabut, D; D'Amico, G; Tan, P

    2010-01-01

    The definition of failure to control bleeding agreed upon at the Baveno IV consensus meeting, included the Adjusted Blood Requirement Index [ABRI: number of blood units/(final-initial hematocrit+0.01)]. ABRI =0.75 denotes failure. However, timing for hematocrit measurements was not defined....... The aims of this study were: (1) to assess the Baveno IV criteria performance to classify treatment success or failure to control bleeding at 5 days, (2) to determine the appropriate timing for hematocrit....

  14. Diagnostic performance of Baveno IV criteria in cirrhotic patients with upper gastrointestinal bleeding: analysis of the F7 liver-1288 study population

    DEFF Research Database (Denmark)

    Thabut, D; D'Amico, G; Tan, P

    2010-01-01

    The definition of failure to control bleeding agreed upon at the Baveno IV consensus meeting, included the Adjusted Blood Requirement Index [ABRI: number of blood units/(final-initial hematocrit+0.01)]. ABRI ≥0.75 denotes failure. However, timing for hematocrit measurements was not defined....... The aims of this study were: (1) to assess the Baveno IV criteria performance to classify treatment success or failure to control bleeding at 5 days, (2) to determine the appropriate timing for hematocrit....

  15. Evaluating the performance of clinical criteria for predicting mismatch repair gene mutations in Lynch syndrome: a comprehensive analysis of 3,671 families.

    Science.gov (United States)

    Steinke, Verena; Holzapfel, Stefanie; Loeffler, Markus; Holinski-Feder, Elke; Morak, Monika; Schackert, Hans K; Görgens, Heike; Pox, Christian; Royer-Pokora, Brigitte; von Knebel-Doeberitz, Magnus; Büttner, Reinhard; Propping, Peter; Engel, Christoph

    2014-07-01

    Carriers of mismatch repair (MMR) gene mutations have a high lifetime risk for colorectal and endometrial cancers, as well as other malignancies. As mutation analysis to detect these patients is expensive and time-consuming, clinical criteria and tumor-tissue analysis are widely used as pre-screening methods. The aim of our study was to evaluate the performance of commonly applied clinical criteria (the Amsterdam I and II Criteria, and the original and revised Bethesda Guidelines) and the results of tumor-tissue analysis in predicting MMR gene mutations. We analyzed 3,671 families from the German HNPCC Registry and divided them into nine mutually exclusive groups with different clinical criteria. A total of 680 families (18.5%) were found to have a pathogenic MMR gene mutation. Among all 1,284 families with microsatellite instability-high (MSI-H) colorectal cancer, the overall mutation detection rate was 53.0%. Mutation frequencies and their distribution between the four MMR genes differed significantly between clinical groups (p small-bowel cancer (p small-bowel cancer were clinically relevant predictors for Lynch syndrome. © 2013 UICC.

  16. Symptom presentations and other characteristics of colorectal cancer patients and the diagnostic performance of the Auckland Regional Grading Criteria for Suspected Colorectal Cancer in the South Auckland population.

    Science.gov (United States)

    Hsiang, John C; Bai, Wayne; Lal, Dinesh

    2013-09-13

    This study reviews the presenting symptoms of colorectal cancer in the ethnically diverse Middlemore Hospital referral population of South Auckland, New Zealand. The performance of the newly introduced Auckland Regional Grading Criteria as prediction tool for selecting colorectal cancer cases referred from primary care was evaluated in this group. Retrospective review of all colorectal cancer (CRC) cases diagnosed between January 2006 and January 2011. Information extracted from case note review was used to grade patients using the Auckland Regional Grading Criteria. A total of 799 patients were included. The commonest symptoms were: rectal bleeding (25.5-42.3%) and change in bowel habit (20.6-26.8%). Low-risk symptoms including abdominal pain (16.3-46.8%) and weight loss (18.4-26.1%) were not uncommon. 64.4% of Maori and 64.9% of Pacific patients had stage III or IV cancers. Pacific patients had more stage IV disease, 37.7% (pAuckland Regional Grading Criteria would miss 24.7% of the patients with CRC in the referral population. While rectal bleeding and change in bowel habit are frequent presenting symptoms, low-risk atypical symptoms including constipation, weight loss and abdominal pain were not uncommon. Significant proportion of Pacific patients present with late-stage disease. The current Auckland Regional grading criteria would miss significant proportion of our study population with colorectal cancer.

  17. Cross-Cultural Scaling Studies in the Development of Probabilistic Teaching Performance Criteria Anchored to Utility and Time Scales.

    Science.gov (United States)

    Pfeiffer, Mark G.; And Others

    Previous cross-cultural scaling studies are incorporated into a training and performance model of the classroom teaching job of the college professor. The model, based on German and American data, describes and sets a norm for the improvement of classroom performance. Eight teaching performance factors and a set of seven continua (six predictors…

  18. Acceptance criteria considerations for miscellaneous wastes

    International Nuclear Information System (INIS)

    Irvine, A.R.; Forsberg, C.W.

    1987-01-01

    EPA standards set forth limitations regarding releases to the accessible environment adjacent to a geologic repository. The NRC criteria pertaining to waste form and engineered barrier performance place certain restrictions on the physical and chemical nature of the waste form and require substantially complete confinement of radioactivity until the high-heat-production period is past. After this period, the annual release of radionuclides from the waste package is normally limited to 1 part in 100,000 of the amounts calculated to be present at 1000-y decay. The regulation permits deviation from these criteria in exceptional circumstances. One such circumstance might be the absence of a significant perturbation in temperature around the stored waste. The lack of significant heat release will eliminate the hydrologic driving force for dispersal of radionuclides. Exceptional circumstances which potentially could justify a less stringent long-term release criterion are: small quantity of radioactivity, the nature of the radioactive species, and the nature of the geology in which the waste is to be emplaced. Because the MW after a suitable decay period have low heat release rates per unit volume, they apparently could be so emplaced in a repository that there would be no compelling need, according to the reasoning presented in 10 CFR 60, for a 1000-y container. Regarding attainment of the specified long-term release rate criterion, neither the solubility limits for the various waste forms nor the conductance of potential migration barriers are currently adequately characterized. The relatively small total heat generation rate for the MW in combination with the usual low volumetric heat generation rate apparently will allow application of migration barriers in a low temperature environment where barrier performance would be expected to be unchanged with time

  19. Criteria CSR

    OpenAIRE

    Vovk, V.; Zateyshikova, O.

    2014-01-01

    In the article the theoretical aspects regarding criteria for assessing CSR proposed by A. Carroll, including: economic, legal, ethical, philanthropic. Based on this, it is proposed to characterize these criteria with respect to the interested parties (stakeholders), including: investors, shareholders suppliers, customers, employees, society and the state. This will make a qualitative assessment of the presence and depth using social responsibility in the company, as well as determine the ext...

  20. Direct-to-physician and direct-to-consumer advertising: Time to have stringent regulations.

    Science.gov (United States)

    Kannan, S; Gowri, S; Tyagi, V; Kohli, S; Jain, R; Kapil, P; Bhardwaj, A

    2015-01-01

    the opinion regarding DTCA, 69.9% physicians had a patient discussing DTCA that was clinically inappropriate. One hundred (64.5%) out of 155 physicians opined that DTCA encourage patients to attend physicians regarding preventive healthcare. On the contrary, 82/155 (52.9%) physicians felt that DTCA would damage the same. Similarly, 69 out of the total 100 patients felt that drug advertisements aid them to have better discussions with their treating physicians. Surprisingly, a large majority (91/100) were of the opinion that only safe drugs are allowed to be advertised. To conclude, from the findings of this study both the physicians and patients should be cautious and not overzealous while dealing with drug advertisements or promotional literature. More stringent scrutiny and issue of WLs or blacklisting of indulging pharmaceutical companies are mandatory by the regulatory agency to contain the same.

  1. Perceptions of the Principal Evaluation Process and Performance Criteria: A Qualitative Study of the Challenge of Principal Evaluation

    Science.gov (United States)

    Faginski-Stark, Erica; Casavant, Christopher; Collins, William; McCandless, Jason; Tencza, Marilyn

    2012-01-01

    Recent federal and state mandates have tasked school systems to move beyond principal evaluation as a bureaucratic function and to re-imagine it as a critical component to improve principal performance and compel school renewal. This qualitative study investigated the district leaders' and principals' perceptions of the performance evaluation…

  2. Derivation and Validation of Systemic Lupus International Collaborating Clinics Classification Criteria for Systemic Lupus Erythematosus

    Science.gov (United States)

    Petri, Michelle; Orbai, Ana-Maria; Alarcón, Graciela S.; Gordon, Caroline; Merrill, Joan T.; Fortin, Paul R.; Bruce, Ian N.; Isenberg, David; Wallace, Daniel J.; Nived, Ola; Sturfelt, Gunnar; Ramsey-Goldman, Rosalind; Bae, Sang-Cheol; Hanly, John G.; Sanchez-Guerrero, Jorge; Clarke, Ann; Aranow, Cynthia; Manzi, Susan; Urowitz, Murray; Gladman, Dafna; Kalunian, Kenneth; Costner, Melissa; Werth, Victoria P.; Zoma, Asad; Bernatsky, Sasha; Ruiz-Irastorza, Guillermo; Khamashta, Munther A.; Jacobsen, Soren; Buyon, Jill P.; Maddison, Peter; Dooley, Mary Anne; van Vollenhoven, Ronald F.; Ginzler, Ellen; Stoll, Thomas; Peschken, Christine; Jorizzo, Joseph L.; Callen, Jeffrey P.; Lim, S. Sam; Fessler, Barri J.; Inanc, Murat; Kamen, Diane L.; Rahman, Anisur; Steinsson, Kristjan; Franks, Andrew G.; Sigler, Lisa; Hameed, Suhail; Fang, Hong; Pham, Ngoc; Brey, Robin; Weisman, Michael H.; McGwin, Gerald; Magder, Laurence S.

    2012-01-01

    Objective The Systemic Lupus Collaborating Clinics (SLICC) revised and validated the American College of Rheumatology (ACR) SLE classification criteria in order to improve clinical relevance, meet stringent methodology requirements and incorporate new knowledge in SLE immunology. Methods The classification criteria were derived from a set of 702 expert-rated patient scenarios. Recursive partitioning was used to derive an initial rule that was simplified and refined based on SLICC physician consensus. SLICC validated the classification criteria in a new validation sample of 690 SLE patients and controls. Results Seventeen criteria were identified. The SLICC criteria for SLE classification requires: 1) Fulfillment of at least four criteria, with at least one clinical criterion AND one immunologic criterion OR 2) Lupus nephritis as the sole clinical criterion in the presence of ANA or anti-dsDNA antibodies. In the derivation set, the SLICC classification criteria resulted in fewer misclassifications than the current ACR classification criteria (49 versus 70, p=0.0082), had greater sensitivity (94% versus 86%, p<0.0001) and equal specificity (92% versus 93%, p=0.39). In the validation set, the SLICC Classification criteria resulted in fewer misclassifications (62 versus 74, p=0.24), had greater sensitivity (97% versus 83%, p<0.0001) but less specificity (84% versus 96%, p<0.0001). Conclusions The new SLICC classification criteria performed well on a large set of patient scenarios rated by experts. They require that at least one clinical criterion and one immunologic criterion be present for a classification of SLE. Biopsy confirmed nephritis compatible with lupus (in the presence of SLE autoantibodies) is sufficient for classification. PMID:22553077

  3. Green Supplier Selection Criteria

    DEFF Research Database (Denmark)

    Nielsen, Izabela Ewa; Banaeian, Narges; Golinska, Paulina

    2014-01-01

    to determine prevalent general and environmental supplier selection criteria and develop a framework which can help decision makers to determine and prioritize suitable green supplier selection criteria (general and environmental). In this research we considered several parameters (evaluation objectives......) to establish suitable criteria for GSS such as their production type, requirements, policy and objectives instead of applying common criteria. At first a comprehensive and deep review on prevalent and green supplier selection literatures performed. Then several evaluation objectives defined to assess the green......Green supplier selection (GSS) criteria arise from an organization inclination to respond to any existing trends in environmental issues related to business management and processes, so GSS is integrating environmental thinking into conventional supplier selection. This research is designed...

  4. Synthetic Peptides to Target Stringent Response-Controlled Virulence in a Pseudomonas aeruginosa Murine Cutaneous Infection Model

    Directory of Open Access Journals (Sweden)

    Daniel Pletzer

    2017-09-01

    Full Text Available Microorganisms continuously monitor their surroundings and adaptively respond to environmental cues. One way to cope with various stress-related situations is through the activation of the stringent stress response pathway. In Pseudomonas aeruginosa this pathway is controlled and coordinated by the activity of the RelA and SpoT enzymes that metabolize the small nucleotide secondary messenger molecule (pppGpp. Intracellular ppGpp concentrations are crucial in mediating adaptive responses and virulence. Targeting this cellular stress response has recently been the focus of an alternative approach to fight antibiotic resistant bacteria. Here, we examined the role of the stringent response in the virulence of P. aeruginosa PAO1 and the Liverpool epidemic strain LESB58. A ΔrelA/ΔspoT double mutant showed decreased cytotoxicity toward human epithelial cells, exhibited reduced hemolytic activity, and caused down-regulation of the expression of the alkaline protease aprA gene in stringent response mutants grown on blood agar plates. Promoter fusions of relA or spoT to a bioluminescence reporter gene revealed that both genes were expressed during the formation of cutaneous abscesses in mice. Intriguingly, virulence was attenuated in vivo by the ΔrelA/ΔspoT double mutant, but not the relA mutant nor the ΔrelA/ΔspoT complemented with either gene. Treatment of a cutaneous P. aeruginosa PAO1 infection with anti-biofilm peptides increased animal welfare, decreased dermonecrotic lesion sizes, and reduced bacterial numbers recovered from abscesses, resembling the phenotype of the ΔrelA/ΔspoT infection. It was previously demonstrated by our lab that ppGpp could be targeted by synthetic peptides; here we demonstrated that spoT promoter activity was suppressed during cutaneous abscess formation by treatment with peptides DJK-5 and 1018, and that a peptide-treated relA complemented stringent response double mutant strain exhibited reduced peptide

  5. A pilot study to determine the diagnostic criteria of spiculated masses for BI-RADS MRI category 5: when to perform re-biopsy after discordant pathologic result?

    Science.gov (United States)

    Onishi, Natsuko; Kataoka, Masako; Kanao, Shotaro; Kawai, Makiko; Iima, Mami; Ohashi, Akane; Toi, Masakazu; Togashi, Kaori

    2017-01-01

    This study aimed to investigate (1) the MRI and clinical findings useful to differentiate malignant from benign spiculated masses and (2) the diagnostic criteria of spiculated masses for BI-RADS MRI category 5, for which any non-malignant biopsy result is considered discordant and a re-biopsy is recommended. Spiculated breast masses, depicted by 3.0/1.5-T contrast-enhanced MRI between June 2008 and March 2014, were retrospectively analyzed. Patient's age, lesion size, minimum/average apparent diffusion coefficient values (ADCmin/ADCave), and BI-RADS descriptors were compared between malignant and benign lesions. Based on these results, we assessed criteria to define category 5 spiculated masses with a ≥95 % probability of malignancy and evaluated their diagnostic performance. A total of 140 lesions (Malignant group, n = 131; Benign group, n = 9) were analyzed. Patient's age, lesion size, ADCmin and ADCave showed significant differences between the two groups, while none of the BI-RADS descriptors, including kinetic curve assessment, showed any significant difference in frequency. Multivariate logistic regression analysis demonstrated that patient's age and lesion size were the significant predictive factors of malignancy. Of all the assessed criteria for category 5 spiculated masses, "age >50 years or size >9 mm, or both" were selected as the best criteria to minimize the possibility of unnecessary re-biopsies and inappropriate follow-up for malignancies. Patient's age and lesion size are useful to differentiate malignant from benign spiculated breast masses. In cases with non-malignant biopsy results, spiculated masses with "age >50 years or size >9 mm, or both" are more likely malignant.

  6. Work in support of biosphere assessments for solid radioactive waste disposal. 1. performance assessments, requirements and methodology; criteria for radiological environmental protection

    International Nuclear Information System (INIS)

    Egan, M.J.; Loose, M.; Smith, G.M.; Watkins, B.M.

    2001-10-01

    The first part of this report is intended to assess how the recent Swedish regulatory developments and resulting criteria impose requirements on what should be included in a performance assessment (PA) for the SFR low and medium level waste repository and for a potential deep repository for high level waste. The second part of the report has been prepared by QuantiSci as an input to the development of SSI's PA review methodology. The aim of the third part is to provide research input to the development of radiological protection framework for the environment, for use in Sweden. This is achieved through a review of various approaches used in other fields

  7. Accommodating Those Most at Risk. Responding to a Mismatch in Programme Selection Criteria and Foundation Biology Performance

    Science.gov (United States)

    Kirby, Nicola F.; Dempster, Edith R.

    2015-01-01

    In South Africa, foundation programmes are a well-established alternative access route to tertiary science study for educationally disadvantaged students. Student access to, and performance in, one such foundation programme has been researched by the authors seeking opportunities to improve student retention. The biology module in particular has…

  8. An Evaluation of Computerized Tests as Predictors of Job Performance: II. Differential Validity for Global and Job Element Criteria

    Science.gov (United States)

    1976-01-01

    provide more reliable and valid measures of performance than the commonly used global marks (Lawshe, 1952; Guion , 1965; Mecham & McCormick, 1969). Thus...Memory Test Radio Code Aptitude Test Electronic Technician Selection Test Shop Practices AFOT GCT ARI MECH CLER SONR RADO ETST SHOP...multiple regression for a global criterion were carried out using a modification of the methodology used in a study by Guion (1965). The

  9. Achieving stringent climate targets. An analysis of the role of transport and variable renewable energies using energy-economy-climate models

    Energy Technology Data Exchange (ETDEWEB)

    Pietzcker, Robert Carl

    2014-07-01

    the demonstration phase. Delaying stringent policies and extending the current period of fragmented and weak action will substantially increase mitigation costs, such that stringent climate targets might be pushed out of reach. Should the current weak climate policies be extended until 2030, the transitional mitigation costs for keeping the 2 C target would increase three-fold compared to a world in which global cooperative action is decided on in 2015 and where first deep emission reductions are achieved in 2020. In case of technology limitations, the urgency of reaching a global climate agreement is even higher. In this thesis, we performed a comprehensive analysis of stringent mitigation scenarios and their economic implications, with a special focus on VRE deployment and transport decarbonization. Based on extensive modeling work and global cross-model analyses, this thesis provides crucial insights and identifies strategies for achieving stringent mitigation targets.

  10. Esophageal surgery in Italy. Criteria to identify the hospital units and the tertiary referral centers entitled to perform it.

    Science.gov (United States)

    Parise, Paolo; Elmore, Ugo; Fumagalli, Uberto; De Manzoni, Giovanni; Giacopuzzi, Simone; Rosati, Riccardo

    2016-06-01

    Esophageal cancer incidence is rapidly increasing in the western countries. Adenocarcinoma has recently become the most frequent subtype because of the changes in lifestyle. As observed for other types of surgery, even for esophageal surgery better results have been observed in centers with high volume of activity. Countries with formal policies of centralization, as Great Britain and The Netherlands, have got lower mortality and longer survival than those obtained before the centralization program introduction and of those countries without centralization programs. However, concerns about accessibility to high volume hospitals for lower level social strata have emerged in different countries. In Italy most of the esophagectomies for cancer are performed in very low volume centers with limited experience. High volume centers with >20 cases/year are few but, even if managing patients with more severe comorbidities have got a lower mortality and a shorter length of stay. The Aim of this paper is to identify the organizational, structural and volume requirements for accreditation of a center as an esophageal surgery center. Special attention must be given to a multidisciplinary approach involving different highly skilled specialists with the creation of a multidisciplinary team and individualized diagnostic and therapeutic pathways.

  11. Thermodynamic performance analysis and optimization of DMC (Dual Miller Cycle) cogeneration system by considering exergetic performance coefficient and total exergy output criteria

    International Nuclear Information System (INIS)

    Ust, Yasin; Arslan, Feyyaz; Ozsari, Ibrahim; Cakir, Mehmet

    2015-01-01

    Miller cycle engines are one of the popular engine concepts that are available for improving performance, reducing fuel consumption and NO x emissions. There are many research studies that investigated the modification of existing conventional engines for operation on a Miller cycle. In this context, a comparative performance analysis and optimization based on exergetic performance criterion, total exergy output and exergy efficiency has been carried out for an irreversible Dual–Miller Cycle cogeneration system having finite-rate of heat transfer, heat leak and internal irreversibilities. The EPC (Exergetic Performance Coefficient) criterion defined as the ratio of total exergy output to the loss rate of availability. Performance analysis has been also extended to the Otto–Miller and Diesel-Miller cogeneration cycles which may be considered as two special cases of the Dual–Miller cycle. The effect of the design parameters such as compression ratio, pressure ratio, cut-off ratio, Miller cycle ratio, heat consumer temperature ratio, allocation ratio and the ratio of power to heat consumed have also been investigated. The results obtained from this paper will provide guidance for the design of Dual–Miller Cycle cogeneration system and can be used for selection of optimal design parameters. - Highlights: • A thermodynamic performance estimation tool for DM cogeneration cycle is presented. • Using the model two special cases OM and dM cogeneration cycles can be analyzed. • The effects of r M , ψ, χ 2 and R have been investigated. • The results evaluate exergy output and environmental aspects together.

  12. A rapid response air quality analysis system for use in projects having stringent quality assurance requirements

    International Nuclear Information System (INIS)

    Bowman, A.W.

    1990-01-01

    This paper describes an approach to solve air quality problems which frequently occur during iterations of the baseline change process. From a schedule standpoint, it is desirable to perform this evaluation in as short a time as possible while budgetary pressures limit the size of the staff available to do the work. Without a method in place to deal with baseline change proposal requests the environment analysts may not be able to produce the analysis results in the time frame expected. Using a concept called the Rapid Response Air Quality Analysis System (RAAS), the problems of timing and cost become tractable. The system could be adapted to assess other atmospheric pathway impacts, e.g., acoustics or visibility. The air quality analysis system used to perform the EA analysis (EA) for the Salt Repository Project (part of the Civilian Radioactive Waste Management Program), and later to evaluate the consequences of proposed baseline changes, consists of three components: Emission source data files; Emission rates contained in spreadsheets; Impact assessment model codes. The spreadsheets contain user-written codes (macros) that calculate emission rates from (1) emission source data (e.g., numbers and locations of sources, detailed operating schedules, and source specifications including horsepower, load factor, and duty cycle); (2) emission factors such as those published by the U.S. Environmental Protection Agency, and (3) control efficiencies

  13. Clinical Neuropathology practice news 1-2014: pyrosequencing meets clinical and analytical performance criteria for routine testing of MGMT promoter methylation status in glioblastoma.

    Science.gov (United States)

    Preusser, Matthias; Berghoff, Anna S; Manzl, Claudia; Filipits, Martin; Weinhäusel, Andreas; Pulverer, Walter; Dieckmann, Karin; Widhalm, Georg; Wöhrer, Adelheid; Knosp, Engelbert; Marosi, Christine; Hainfellner, Johannes A

    2014-01-01

    Testing of the MGMT promoter methylation status in glioblastoma is relevant for clinical decision making and research applications. Two recent and independent phase III therapy trials confirmed a prognostic and predictive value of the MGMT promoter methylation status in elderly glioblastoma patients. Several methods for MGMT promoter methylation testing have been proposed, but seem to be of limited test reliability. Therefore, and also due to feasibility reasons, translation of MGMT methylation testing into routine use has been protracted so far. Pyrosequencing after prior DNA bisulfite modification has emerged as a reliable, accurate, fast and easy-to-use method for MGMT promoter methylation testing in tumor tissues (including formalin fixed and paraffin-embedded samples). We performed an intra- and inter-laboratory ring trial which demonstrates a high analytical performance of this technique. Thus, pyrosequencing- based assessment of MGMT promoter methylation status in glioblastoma meets the criteria of high analytical test performance and can be recommended for clinical application, provided that strict quality control is performed. Our article summarizes clinical indications, practical instructions and open issues for MGMT promoter methylation testing in glioblastoma using pyrosequencing.

  14. Stringent upper limit of CH4 on Mars based on SOFIA/EXES observations

    Science.gov (United States)

    Aoki, S.; Richter, M. J.; DeWitt, C.; Boogert, A.; Encrenaz, T.; Sagawa, H.; Nakagawa, H.; Vandaele, A. C.; Giuranna, M.; Greathouse, T. K.; Fouchet, T.; Geminale, A.; Sindoni, G.; McKelvey, M.; Case, M.; Kasaba, Y.

    2018-03-01

    Discovery of CH4 in the Martian atmosphere has led to much discussion since it could be a signature of biological and/or geological activities on Mars. However, the presence of CH4 and its temporal and spatial variations are still under discussion because of the large uncertainties embedded in the previous observations. We performed sensitive measurements of Martian CH4 by using the Echelon-Cross-Echelle Spectrograph (EXES) onboard the Stratospheric Observatory for Infrared Astronomy (SOFIA) on 16 March 2016, which corresponds to summer (Ls = 123.2∘) in the northern hemisphere on Mars. The high altitude of SOFIA ( 13.7 km) enables us to significantly reduce the effects of terrestrial atmosphere. Thanks to this, SOFIA/EXES improves our chances of detecting Martian CH4 lines because it reduces the impact of telluric CH4 on Martian CH4, and allows us to use CH4 lines in the 7.5 μm band which has less contamination. However, our results show no unambiguous detection of Martian CH4. The Martian disk was spatially resolved into 3 × 3 areas, and the upper limits on the CH4 volume mixing ratio range from 1 to 9 ppb across the Martian atmosphere, which is significantly less than detections in several other studies. These results emphasize that release of CH4 on Mars is sporadic and/or localized if the process is present.

  15. Work in support of biosphere assessments for solid radioactive waste disposal. 1. performance assessments, requirements and methodology; criteria for radiological environmental protection

    Energy Technology Data Exchange (ETDEWEB)

    Egan, M.J.; Loose, M.; Smith, G.M.; Watkins, B.M. [QuantiSci Ltd., Henley-on-Thames (United Kingdom)

    2001-10-01

    The first part of this report is intended to assess how the recent Swedish regulatory developments and resulting criteria impose requirements on what should be included in a performance assessment (PA) for the SFR low and medium level waste repository and for a potential deep repository for high level waste. The second part of the report has been prepared by QuantiSci as an input to the development of SSI's PA review methodology. The aim of the third part is to provide research input to the development of radiological protection framework for the environment, for use in Sweden. This is achieved through a review of various approaches used in other fields.

  16. The Future Through the Past: The Use of Analog Sites for Design Criteria and Long Term Performance Assessment of Evapotranspiration Landfill Covers

    Energy Technology Data Exchange (ETDEWEB)

    Shafer, D. S.; Miller, J. J.; Young, M. H.; Edwards, S. C.; Rawlinson, S. E.

    2002-02-26

    There is growing support for using evapotranspiration (ET) covers for closure of low-level waste (LLW) and other types of waste disposal sites, particularly in the lower latitude arid regions of the western United States. At the Nevada Test Site (NTS), monolayer ET covers are the baseline technology for closure of LLW and mixed LLW cells. To better predict the long-term performance of monolayer ET covers, as well as to identify design criteria that will potentially improve their performance, the properties of, and processes occurring on, analog sites for ET covers on the NTS are being studied. The project is funded through the Subsurface Contaminants Focus Area of the U.S. Department of Energy. Four analog sites on the NTS have been selected to predict performance of ET covers over a 1,000-year compliance period. Two sites are relatively recently disturbed (within the last 50 years) and have been selected to evaluate processes and changes on ET covers for the early period after active cover maintenance is discontinued. Two other sites, late to mid-Holocene in age, are intended as analogs for the end of the compliance period (1,000 years or more); both surfaces are abandoned alluvial/colluvial deposits. The history of the early post-institutional control analog sites are being evaluated by an archaeologist to help determine when the sites were last disturbed or modified, and the mode of disturbance to help set baseline conditions. Similar to other ''landforms,'' ET covers will evolve over time because of pedogenic, biotic, and climatic processes. Properties of analog sites that could affect ET water balance performance will be evaluated to help understand ET cover performance over time.

  17. The implementation of modern digital technology in x-ray medical diagnosis in Republic of Moldova - a stringent necessity

    International Nuclear Information System (INIS)

    Rosca, Andrei

    2011-01-01

    The study includes analyses of current technical state of radiodiagnostic equipment from the Public Medico-Sanitary Institution of Ministry of Health of Republic of Moldova (IMSP MS RM). The traditional radiodiagnostic apparatuses were morally and physically outrun at 96,6% (in regional MSPI - 93,5%), inclusive the dental one - 92,0% (in raional MSPI - 97,2%), X-Ray exam -100%, mobile - 84,1% etc. The exploitation of the traditional radiodiagnostic apparatuses with high degree of physical and moral wear essentially diminished the quality of profile investigation, creates premises for diagnostic error perpetrating, increase the collective ionizing irradiation of population etc. In recent years the subvention of MSPI HM RM with digital radiodiagnostic equipment was started. This process is very hard unfold because of grave socio-economic crises in Republic of Moldova. Despite these obstacles the subvention of MSPI HM RM with digital equipment represents a stringent necessity and a time request.

  18. The mechanism of heterogeneous beta-lactam resistance in MRSA: key role of the stringent stress response.

    Directory of Open Access Journals (Sweden)

    Choonkeun Kim

    Full Text Available All methicillin resistant S. aureus (MRSA strains carry an acquired genetic determinant--mecA or mecC--which encode for a low affinity penicillin binding protein -PBP2A or PBP2A'--that can continue the catalysis of peptidoglycan transpeptidation in the presence of high concentrations of beta-lactam antibiotics which would inhibit the native PBPs normally involved with the synthesis of staphylococcal cell wall peptidoglycan. In contrast to this common genetic and biochemical mechanism carried by all MRSA strains, the level of beta-lactam antibiotic resistance shows a very wide strain to strain variation, the mechanism of which has remained poorly understood. The overwhelming majority of MRSA strains produce a unique--heterogeneous--phenotype in which the great majority of the bacteria exhibit very poor resistance often close to the MIC value of susceptible S. aureus strains. However, cultures of such heterogeneously resistant MRSA strains also contain subpopulations of bacteria with extremely high beta-lactam MIC values and the resistance level and frequency of the highly resistant cells in such strain is a characteristic of the particular MRSA clone. In the study described in this communication, we used a variety of experimental models to understand the mechanism of heterogeneous beta-lactam resistance. Methicillin-susceptible S. aureus (MSSA that received the mecA determinant in the laboratory either on a plasmid or in the form of a chromosomal SCCmec cassette, generated heterogeneously resistant cultures and the highly resistant subpopulations that emerged in these models had increased levels of PBP2A and were composed of bacteria in which the stringent stress response was induced. Each of the major heterogeneously resistant clones of MRSA clinical isolates could be converted to express high level and homogeneous resistance if the growth medium contained an inducer of the stringent stress response.

  19. Global energy scenarios meeting stringent CO2 constraints - cost-effective fuel choices in the transportation sector

    International Nuclear Information System (INIS)

    Azar, Christian; Lindgren, Kristian; Andersson, B.A.

    2003-01-01

    The purpose of this paper is to assess fuel choices in the transportation sector under stringent global carbon constraints. Three key questions are asked: (i) when is it cost-effective to carry out the transition away from gasoline/diesel; (ii) to which fuel is it cost-effective to shift; and (iii) in which sector is biomass most cost-effectively used? These questions are analyzed using a global energy systems model (GET 1.0), with a transportation module, where vehicle costs (fuel cell, reformer and storage tank), infrastructure and primary energy availability are treated explicitly. The model is run under the assumption that atmospheric concentrations of CO 2 should be stabilized at 400 ppm. Three main results emerge: (i) despite the stringent CO 2 constraints, oil-based fuels remain dominant in the transportation sector over the next 50 years; and (ii) once a transition towards alternative fuels takes place, the preferred choice of fuel is hydrogen, even if we assume that hydrogen fuel cell vehicles are substantially more costly than methanol fuel cell vehicles. There may, under some circumstances, be a transient period of several decades with a significant share of methanol in the transportation sector. (iii) Biomass is most cost-effectively used in the heat and process heat sectors. If carbon sequestration from biomass is allowed, biomass is primarily used for hydrogen generation since small-scale heat applications are not suitable for carbon sequestration. Detailed sensitivity analyses show that these results are robust with respect to several parameters. Some policy conclusions are drawn

  20. Key Performance Criteria Affecting the Most the Safety of a Nuclear Waste Long Term Storage : A Case Study Commissioned by CEA

    Energy Technology Data Exchange (ETDEWEB)

    Marvy, A.; Lioure, A; Heriard-Dubreuil, G.; Gadbois, S.; Schneider, T.; Schieber, C.

    2003-02-24

    As part of the work scope set in the French law on high level long lived waste R&D passed in 1991, CEA is conducting a research program to establish the scientific basis and assess the feasibility of long term storage as an option for the safe management of nuclear waste for periods as long as centuries. This goal is a significant departure from the current industrial practice where storage facilities are usually built to last only a few decades. From a technical viewpoint such an extension in time seems feasible provided care and maintenance is exercised. Considering such long periods of time, the risk for Society of loosing oversight and control of such a facility is real, which triggers the question of whether and how long term storage safety can be actually achieved. Therefore CEA commissioned a study (1) in which MUTADIS Consultants (2) and CEPN (3) were both involved. The case study looks into several past and actual human enterprises conducted over significant periods o f time, one of them dating back to the end of the 18th century, and all identified out of the nuclear field. Then-prevailing societal behavior and organizational structures are screened out to show how they were or are still able to cope with similar oversight and control goals. As a result, the study group formulated a set of performance criteria relating to issues like responsibility, securing funds, legal and legislative implications, economic sustainable development, all being areas which are not traditionally considered as far as technical studies are concerned. These criteria can be most useful from the design stage onward, first in an attempt to define the facility construction and operating guiding principles, and thereafter to substantiate the safety case for long term storage and get geared to the public dialogue on that undertaking should it become a reality.

  1. A look at new key performance criteria that could most affect the safety of long term storage of nuclear waste. A case study commissioned by CEA

    International Nuclear Information System (INIS)

    Marvy, A.; Lioure, A.; Heriard-Dubreuil, G.; Gadbois, S.; Schneider, T.; Schieber, C

    2002-01-01

    As part of the work scope set in the French law on high level long lived waste R and D passed in 1991, CEA is conducting research work to establish the scientific basis and assess the feasibility of long term storage as an option for the safe management of nuclear waste for periods as long as a few centuries. This goal is a significant departure from current industrial practice where storage facilities are usually built to last only a few decades. From a technical viewpoint such an extension in time seems feasible provided care and maintenance is exercised. Considering such long periods of time risk for Society of loosing oversight and control of such a facility is real which triggers the question of whether and how long term storage safety can be actually achieved. Therefore CEA commissioned a study in which MUTADIS Consultants and CEPN were both involved. The case study looks into several past and actual human enterprises conducted over significant periods of time - one dating back to the end of the 18th century - and identified off the nuclear field. Then-prevailing societal behaviour and organizational structures are screened out to show how they were and are still able to cope with similar oversight and control goals. As a result the study group obtained a set of performance criteria relating to issues like responsibility, securing funds, legal and legislative implications, economic sustainable development, all being areas which are not traditionally considered when technical studies are conducted. These criteria can be most useful from the design stage onward, first in an attempt to define the facility construction and operating guiding principles, and thereafter to substantiate the safety case for long term storage and get geared to the public dialogue on that undertaking should it become a reality. (author)

  2. Nuclear controls are stringent

    International Nuclear Information System (INIS)

    Sonnekus, D.

    1983-01-01

    The peace-time application of nuclear power in South Africa, the organisations concerned and certain provisions laid down by the Act on Nuclear Energy, aimed at safeguarding the general public, are discussed

  3. Performance criteria for testosterone measurements based on biological variation in adult males: recommendations from the Partnership for the Accurate Testing of Hormones.

    Science.gov (United States)

    Yun, Yeo-Min; Botelho, Julianne Cook; Chandler, Donald W; Katayev, Alex; Roberts, William L; Stanczyk, Frank Z; Vesper, Hubert W; Nakamoto, Jon M; Garibaldi, Luigi; Clarke, Nigel J; Fitzgerald, Robert L

    2012-12-01

    Testosterone measurements that are accurate, reliable, and comparable across methodologies are crucial to improving public health. Current US Food and Drug Administration-cleared testosterone assays have important limitations. We sought to develop assay performance requirements on the basis of biological variation that allow physiologic changes to be distinguished from assay analytical errors. From literature review, the technical advisory subcommittee of the Partnership for the Accurate Testing of Hormones compiled a database of articles regarding analytical and biological variability of testosterone. These data, mostly from direct immunoassay-based methodologies, were used to specify analytical performance goals derived from within- and between-person variability of testosterone. The allowable limits of desirable imprecision and bias on the basis of currently available biological variation data were 5.3% and 6.4%, respectively. The total error goal was 16.7%. From recent College of American Pathologists proficiency survey data, most currently available testosterone assays missed these analytical performance goals by wide margins. Data from the recently established CDC Hormone Standardization program showed that although the overall mean bias of selected certified assays was within 6.4%, individual sample measurements could show large variability in terms of precision, bias, and total error. Because accurate measurement of testosterone across a wide range of concentrations [approximately 2-2000 ng/dL (0.069-69.4 nmol/L)] is important, we recommend using available data on biological variation to calculate performance criteria across the full range of expected values. Additional studies should be conducted to obtain biological variation data on testosterone from women and children, and revisions should be made to the analytical goals for these patient populations. © 2012 American Association for Clinical Chemistry

  4. The effects of performance criteria including accounting, market, and economy on the quality of financial reporting: A case study on Tehran Stock Exchange

    Directory of Open Access Journals (Sweden)

    Mohammad Mahdi Hosseini

    2013-01-01

    Full Text Available This research studies the effects of performance criteria (accounting, market and economy on the quality of financial reporting in Iran. To evaluate the variable financial reporting quality, the scores given to each company are applied based on the checklist introduced by Iranian Association of Certified Public Accountants and used for the disclosure of the information of the annual financial statements of companies. The statistical population of this research consists of the companies listed on Tehran Stock Exchange over the period 2006-2011. This research, which is classified as applied research, uses the methods of multivariate regression test. The data and hypotheses of this research are analyzed and tested using correlation test and means difference test. The results of the tests conducted on 99 companies indicate that there is a significant and positive relation between the rate of return on equity and the equality of financial reporting. There is also a significant and positive relation between earnings per share and the equality of financial reporting. However, there is no relationship between QTOBIN and the equality of financial reporting. Finally, our results indicate there is a significant and positive relation between market value-added and the equality of financial reporting.

  5. Perspectives on the revised Ghent criteria for the diagnosis of Marfan syndrome

    Science.gov (United States)

    von Kodolitsch, Yskert; De Backer, Julie; Schüler, Helke; Bannas, Peter; Behzadi, Cyrus; Bernhardt, Alexander M; Hillebrand, Mathias; Fuisting, Bettina; Sheikhzadeh, Sara; Rybczynski, Meike; Kölbel, Tilo; Püschel, Klaus; Blankenberg, Stefan; Robinson, Peter N

    2015-01-01

    Three international nosologies have been proposed for the diagnosis of Marfan syndrome (MFS): the Berlin nosology in 1988; the Ghent nosology in 1996 (Ghent-1); and the revised Ghent nosology in 2010 (Ghent-2). We reviewed the literature and discussed the challenges and concepts of diagnosing MFS in adults. Ghent-1 proposed more stringent clinical criteria, which led to the confirmation of MFS in only 32%–53% of patients formerly diagnosed with MFS according to the Berlin nosology. Conversely, both the Ghent-1 and Ghent-2 nosologies diagnosed MFS, and both yielded similar frequencies of MFS in persons with a causative FBN1 mutation (90% for Ghent-1 versus 92% for Ghent-2) and in persons not having a causative FBN1 mutation (15% versus 13%). Quality criteria for diagnostic methods include objectivity, reliability, and validity. However, the nosology-based diagnosis of MFS lacks a diagnostic reference standard and, hence, quality criteria such as sensitivity, specificity, or accuracy cannot be assessed. Medical utility of diagnosis implies congruency with the historical criteria of MFS, as well as with information about the etiology, pathogenesis, diagnostic triggers, prognostic triggers, and potential complications of MFS. In addition, social and psychological utilities of diagnostic criteria include acceptance by patients, patient organizations, clinicians and scientists, practicability, costs, and the reduction of anxiety. Since the utility of a diagnosis or exclusion of MFS is context-dependent, prioritization of utilities is a strategic decision in the process of nosology development. Screening tests for MFS should be used to identify persons with MFS. To confirm the diagnosis of MFS, Ghent-1 and Ghent-2 perform similarly, but Ghent-2 is easier to use. To maximize the utility of the diagnostic criteria of MFS, a fair and transparent process of nosology development is essential. PMID:26124674

  6. Perspectives on the revised Ghent criteria for the diagnosis of Marfan syndrome.

    Science.gov (United States)

    von Kodolitsch, Yskert; De Backer, Julie; Schüler, Helke; Bannas, Peter; Behzadi, Cyrus; Bernhardt, Alexander M; Hillebrand, Mathias; Fuisting, Bettina; Sheikhzadeh, Sara; Rybczynski, Meike; Kölbel, Tilo; Püschel, Klaus; Blankenberg, Stefan; Robinson, Peter N

    2015-01-01

    Three international nosologies have been proposed for the diagnosis of Marfan syndrome (MFS): the Berlin nosology in 1988; the Ghent nosology in 1996 (Ghent-1); and the revised Ghent nosology in 2010 (Ghent-2). We reviewed the literature and discussed the challenges and concepts of diagnosing MFS in adults. Ghent-1 proposed more stringent clinical criteria, which led to the confirmation of MFS in only 32%-53% of patients formerly diagnosed with MFS according to the Berlin nosology. Conversely, both the Ghent-1 and Ghent-2 nosologies diagnosed MFS, and both yielded similar frequencies of MFS in persons with a causative FBN1 mutation (90% for Ghent-1 versus 92% for Ghent-2) and in persons not having a causative FBN1 mutation (15% versus 13%). Quality criteria for diagnostic methods include objectivity, reliability, and validity. However, the nosology-based diagnosis of MFS lacks a diagnostic reference standard and, hence, quality criteria such as sensitivity, specificity, or accuracy cannot be assessed. Medical utility of diagnosis implies congruency with the historical criteria of MFS, as well as with information about the etiology, pathogenesis, diagnostic triggers, prognostic triggers, and potential complications of MFS. In addition, social and psychological utilities of diagnostic criteria include acceptance by patients, patient organizations, clinicians and scientists, practicability, costs, and the reduction of anxiety. Since the utility of a diagnosis or exclusion of MFS is context-dependent, prioritization of utilities is a strategic decision in the process of nosology development. Screening tests for MFS should be used to identify persons with MFS. To confirm the diagnosis of MFS, Ghent-1 and Ghent-2 perform similarly, but Ghent-2 is easier to use. To maximize the utility of the diagnostic criteria of MFS, a fair and transparent process of nosology development is essential.

  7. THREE THEORIES OF COGNITIVE REPRESENTATION AND CRITERIA FOR EVALUATING TRAINING EFFECTS

    NARCIS (Netherlands)

    Tomic, W.; Kingma, J.

    2008-01-01

    The development of cognitive representation is the main theme of the three classic theories on how children learn new concepts (Piaget, Bruner, Vygotsky). However, these theories do not agree on evaluation standards for training effectiveness. According to Piaget, it is only when stringent criteria

  8. Sensitivity and Specificity of Proposed DSM-5 Criteria for Autism Spectrum Disorder in Toddlers

    Science.gov (United States)

    Barton, Marianne L.; Robins, Diana L.; Jashar, Dasal; Brennan, Laura; Fein, Deborah

    2013-01-01

    Autism spectrum disorder (ASD) diagnosis is based on behavioral presentation; changes in conceptual models or defining behaviors may significantly impact diagnosis and uptake of ASD-specific interventions. The literature examining impact of DSM-5 criteria is equivocal. Toddlers may be especially vulnerable to the stringent requirements of…

  9. Stringently Defined Otitis Prone Children Demonstrate Deficient Naturally Induced Mucosal Antibody Response toMoraxella catarrhalisProteins.

    Science.gov (United States)

    Ren, Dabin; Murphy, Timothy F; Lafontaine, Eric R; Pichichero, Michael E

    2017-01-01

    Moraxella catarrhalis ( Mcat ) is a prominent mucosal pathogen causing acute otitis media (AOM). We studied Mcat nasopharyngeal (NP) colonization, AOM frequency and mucosal antibody responses to four vaccine candidate Mcat proteins: outer membrane protein (OMP) CD, oligopeptide permease (Opp) A, hemagglutinin (Hag), and Pilin A clade 2 (PilA2) from stringently defined otitis prone (sOP) children, who experience the greatest burden of disease, compared to non-otitis prone (NOP) children. sOP children had higher NP colonization of Mcat (30 vs. 22%, P  = 0.0003) and Mcat -caused AOM rates (49 vs. 24%, P  P  P  = 0.018), Hag (IgG and IgA, both P  P  P  = 0.039) and PilA2 ( P  = 0.0076), and IgA to OMP CD ( P  = 0.010), OppA ( P  = 0.030), and PilA2 ( P  = 0.043) were associated with lower carriage of Mcat in NOP but not sOP children. Higher levels of mucosal IgG to OMP CD ( P  = 0.0070) and Hag ( P  = 0.0003), and IgA to Hag ( P  = 0.0067) at asymptomatic colonization than those at onset of AOM were associated with significantly lower rate of Mcat NP colonization progressing to AOM in NOP compared to sOP children (3 vs. 26%, P  NP colonization and NP colonization progressing to Mcat -caused AOM. Enhancing Mcat antigen-specific mucosal immune responses to levels higher than achieved by natural exposure will be necessary to prevent AOM in sOP children.

  10. Stringent constraints on the dark matter annihilation cross section from subhalo searches with the Fermi Gamma-Ray Space Telescope

    Energy Technology Data Exchange (ETDEWEB)

    Berlin, Asher; Hooper, Dan

    2014-01-01

    The dark matter halo of the Milky Way is predicted to contain a very large number of smaller subhalos. As a result of the dark matter annihilations taking place within such objects, the most nearby and massive subhalos could appear as point-like or spatially extended gamma-ray sources, without observable counterparts at other wavelengths. In this paper, we use the results of the Aquarius simulation to predict the distribution of nearby subhalos, and compare this to the characteristics of the unidentified gamma-ray sources observed by the Fermi Gamma-Ray Space Telescope. Focusing on the brightest high latitude sources, we use this comparison to derive limits on the dark matter annihilation cross section. For dark matter particles lighter than ~200 GeV, the resulting limits are the strongest obtained to date, being modestly more stringent than those derived from observations of dwarf galaxies or the Galactic Center. We also derive independent limits based on the lack of unidentified gamma-ray sources with discernible spatial extension, but these limits are a factor of ~2-10 weaker than those based on point-like subhalos. Lastly, we note that four of the ten brightest high-latitude sources exhibit a similar spectral shape, consistent with 30-60 GeV dark matter particles annihilating to b quarks with an annihilation cross section on the order of sigma v ~ (5-10) x 10^-27 cm^3/s, or 8-10 GeV dark matter particles annihilating to taus with sigma v ~ (2.0-2.5) x 10^-27 cm^3/s.

  11. Creating a New Learning Community: A Case Study of School Leaders' Perceptions of the Baldrige Criteria for Performance Excellence and Their Implementation in a Suburban School District

    Science.gov (United States)

    Adams, Denean

    2013-01-01

    The Baldrige Criteria for Performance Excellence (Baldrige categories) are increasingly being used throughout the health, education, and business sectors to drive continuous improvement in quality organizations. In each industry, specific categories are available to assist in identifying quality practices deployed throughout an organization. The…

  12. Côte D’Ivoire; Fifth Review Under the Three-Year Arrangement Under the Extended Credit Facility and Requests for Modification of Performance Criteria and Extension of the Current Arrangement

    OpenAIRE

    International Monetary Fund

    2014-01-01

    This paper discusses Côte d’Ivoire’s Fifth Review Under the Three-Year Arrangement Under the Extended Credit Facility (ECF) and Requests for Modification of Performance Criteria (PC) and Extension of the Current Arrangement. Program performance has been strong. All end-December PCs and all but one indicative target were met. On the downside, fiscal discipline and structural reform momentum could be adversely affected during the run-up to the October 2015 presidential elections. The IMF staff ...

  13. Time Line for Noncopers to Pass Return-to-Sports Criteria After Anterior Cruciate Ligament Reconstruction

    Science.gov (United States)

    Hartigan, Erin H.; Axe, Michael J.; Snyder-Mackler, Lynn

    2013-01-01

    STUDY DESIGN Randomized clinical trial. OBJECTIVES Determine effective interventions for improving readiness to return to sports post-operatively in patients with complete, unilateral, anterior cruciate ligament (ACL) rupture who do not compensate well after the injury (noncopers). Specifically, we compared the effects of 2 preoperative interventions on quadriceps strength and functional outcomes. BACKGROUND The percentage of athletes who return to sports after ACL reconstruction varies considerably, possibly due to differential responses after acute ACL rupture and different management. Prognostic data for noncopers following ACL reconstruction is absent in the literature. METHODS Forty noncopers were randomly assigned to receive either progressive quadriceps strength-training exercises (STR group) or perturbation training in conjunction with strength-training exercises (PERT group) for 10 preoperative rehabilitation sessions. Postoperative rehabilitation was similar between groups. Data on quadriceps strength indices [(involved limb/uninvolved limb force) ×100], 4 hop score indices, and 2 self-report questionnaires were collected preoperatively and 3, 6, and 12 months postoperatively. Mann-Whitney U tests were used to compare functional differences between the groups. Chi-square tests were used to compare frequencies of passing functional criteria and reasons for differences in performance between groups postoperatively. RESULTS Functional outcomes were not different between groups, except a greater number of patients in the PERT group achieved global rating scores (current knee function expressed as a percentage of overall knee function prior to injury) necessary to pass return-to-sports criteria 6 and 12 months after surgery. Mean scores for each functional outcome met return-to-sports criteria 6 and 12 months postoperatively. Frequency counts of individual data, however, indicated that 5% of noncopers passed RTS criteria at 3, 48% at 6, and 78% at 12 months

  14. Choice of external criteria in back pain research: Does it matter? Recommendations based on analysis of responsiveness

    DEFF Research Database (Denmark)

    Lauridsen, Henrik H; Hartvigsen, Jan; Korsholm, Lars

    2007-01-01

    standardised response mean (SRM). Results demonstrated small variations in ROC(auc) across the external criteria for all outcome measures. 7% more patients were classified as improved in the group receiving the 15-point TQ compared to the 7-point TQ (stringent standard). SRMs were higher for the retrospective......Understanding a change score is indispensable for interpretation of results from clinical studies. One way of determining the relevance of change scores is through the use of transition questions that assesses patients' retrospective perception of treatment effect. Unfortunately, results from...... scale evaluating the importance of the perceived change. Four external criteria were generated using both stringent and less stringent standards to dichotomise patients. Discrimination was determined using area under the receiver operating characteristic curve (ROC(auc)) and responsiveness using...

  15. Dual Regulation of Bacillus subtilis kinB Gene Encoding a Sporulation Trigger by SinR through Transcription Repression and Positive Stringent Transcription Control

    Directory of Open Access Journals (Sweden)

    Yasutaro Fujita

    2017-12-01

    Full Text Available It is known that transcription of kinB encoding a trigger for Bacillus subtilis sporulation is under repression by SinR, a master repressor of biofilm formation, and under positive stringent transcription control depending on the adenine species at the transcription initiation nucleotide (nt. Deletion and base substitution analyses of the kinB promoter (PkinB region using lacZ fusions indicated that either a 5-nt deletion (Δ5, nt -61/-57, +1 is the transcription initiation nt or the substitution of G at nt -45 with A (G-45A relieved kinB repression. Thus, we found a pair of SinR-binding consensus sequences (GTTCTYT; Y is T or C in an inverted orientation (SinR-1 between nt -57/-42, which is most likely a SinR-binding site for kinB repression. This relief from SinR repression likely requires SinI, an antagonist of SinR. Surprisingly, we found that SinR is essential for positive stringent transcription control of PkinB. Electrophoretic mobility shift assay (EMSA analysis indicated that SinR bound not only to SinR-1 but also to SinR-2 (nt -29/-8 consisting of another pair of SinR consensus sequences in a tandem repeat arrangement; the two sequences partially overlap the ‘-35’ and ‘-10’ regions of PkinB. Introduction of base substitutions (T-27C C-26T in the upstream consensus sequence of SinR-2 affected positive stringent transcription control of PkinB, suggesting that SinR binding to SinR-2 likely causes this positive control. EMSA also implied that RNA polymerase and SinR are possibly bound together to SinR-2 to form a transcription initiation complex for kinB transcription. Thus, it was suggested in this work that derepression of kinB from SinR repression by SinI induced by Spo0A∼P and occurrence of SinR-dependent positive stringent transcription control of kinB might induce effective sporulation cooperatively, implying an intimate interplay by stringent response, sporulation, and biofilm formation.

  16. Laser Safety Inspection Criteria

    International Nuclear Information System (INIS)

    Barat, K

    2005-01-01

    A responsibility of the Laser Safety Officer (LSO) is to perform laser safety audits. The American National Standard Z136.1 Safe use of Lasers references this requirement in several sections: (1) Section 1.3.2 LSO Specific Responsibilities states under Hazard Evaluation, ''The LSO shall be responsible for hazards evaluation of laser work areas''; (2) Section 1.3.2.8, Safety Features Audits, ''The LSO shall ensure that the safety features of the laser installation facilities and laser equipment are audited periodically to assure proper operation''; and (3) Appendix D, under Survey and Inspections, it states, ''the LSO will survey by inspection, as considered necessary, all areas where laser equipment is used''. Therefore, for facilities using Class 3B and or Class 4 lasers, audits for laser safety compliance are expected to be conducted. The composition, frequency and rigueur of that inspection/audit rests in the hands of the LSO. A common practice for institutions is to develop laser audit checklists or survey forms. In many institutions, a sole Laser Safety Officer (LSO) or a number of Deputy LSO's perform these audits. For that matter, there are institutions that request users to perform a self-assessment audit. Many items on the common audit list and the associated findings are subjective because they are based on the experience and interest of the LSO or auditor in particular items on the checklist. Beam block usage is an example; to one set of eyes a particular arrangement might be completely adequate, while to another the installation may be inadequate. In order to provide more consistency, the National Ignition Facility Directorate at Lawrence Livermore National Laboratory (NIF-LLNL) has established criteria for a number of items found on the typical laser safety audit form. These criteria are distributed to laser users, and they serve two broad purposes: first, it gives the user an expectation of what will be reviewed by an auditor, and second, it is an

  17. Environmental quality and sustainability in the province of Reggio Emilia (Italy): using multi-criteria analysis to assess and compare municipal performance.

    Science.gov (United States)

    Ferrarini, A; Bodini, A; Becchi, M

    2001-10-01

    Sustainability has become an increasingly significant issue, although practical implementation remains difficult. In Italy, promoting sustainability is particularly problematic at the provincial and municipal level, where the lack of resources and expertise, and the effects of uncoordinated policies make it difficult to achieve minimum requirements to make sustainable policies operational. One essential requirement is knowledge of baseline environmental conditions in each municipality. In the province of Reggio Emilia (Northern Italy) Legambiente, an environmental association, launched an initiative called 'Ecopaese' aimed at gathering data on environmental conditions and stimulating local administrations to implement sustainable policies. To this end, the state of the environment in the 45 municipalities within the province has been monitored using 25 indicators. Their values have been used to rank the municipalities by multiple criteria analysis (MCA). The results of this comparative approach provide information about the level of sustainability attained in the province as a whole as well as in the single municipalities. It is hoped that it will provide the basis for direct action plans at the provincial level by identifying areas for remedial action, as recommended by Agenda 21, the declaration adopted by many countries attending the Rio Summit in 1992.

  18. Curriculum content, structure and ECTS for European dental schools. Part II: methods of learning and teaching, assessment procedures and performance criteria.

    NARCIS (Netherlands)

    Plasschaert, A.J.M.; Manogue, M.; Lindh, C.; McLoughlin, J.; Murtomaa, H.; Nattestad, A.; Sanz, M.

    2007-01-01

    This paper presents a brief context of dental undergraduate curricular structure and content and lays out the Association for Dental Education in Europe's views on requirements and recommendations for learning, teaching and assessment procedures/performance.

  19. Are More Stringent NCLB State Accountability Systems Associated with Better Student Outcomes? An Analysis of NAEP Results across States

    Science.gov (United States)

    Wei, Xin

    2012-01-01

    This study developed a comprehensive measure of the stringency level of NCLB states' accountability systems, including the strength of their annual measurable objectives, confidence intervals, performance indexing, retesting, minimum subgroup size, and the difficulty levels of proficiency standards. This study related accountability stringency in…

  20. User Performance Evaluation of Four Blood Glucose Monitoring Systems Applying ISO 15197:2013 Accuracy Criteria and Calculation of Insulin Dosing Errors.

    Science.gov (United States)

    Freckmann, Guido; Jendrike, Nina; Baumstark, Annette; Pleus, Stefan; Liebing, Christina; Haug, Cornelia

    2018-04-01

    The international standard ISO 15197:2013 requires a user performance evaluation to assess if intended users are able to obtain accurate blood glucose measurement results with a self-monitoring of blood glucose (SMBG) system. In this study, user performance was evaluated for four SMBG systems on the basis of ISO 15197:2013, and possibly related insulin dosing errors were calculated. Additionally, accuracy was assessed in the hands of study personnel. Accu-Chek ® Performa Connect (A), Contour ® plus ONE (B), FreeStyle Optium Neo (C), and OneTouch Select ® Plus (D) were evaluated with one test strip lot. After familiarization with the systems, subjects collected a capillary blood sample and performed an SMBG measurement. Study personnel observed the subjects' measurement technique. Then, study personnel performed SMBG measurements and comparison measurements. Number and percentage of SMBG measurements within ± 15 mg/dl and ± 15% of the comparison measurements at glucose concentrations performed by lay-users. The study was registered at ClinicalTrials.gov (NCT02916576). Ascensia Diabetes Care Deutschland GmbH.

  1. Laser Safety Inspection Criteria

    International Nuclear Information System (INIS)

    Barat, K.

    2005-01-01

    A responsibility of the Laser Safety Officer (LSO) is to perform laser audits. The American National Standard Z136.1 Safe Use of Lasers references this requirement through several sections. One such reference is Section 1.3.2.8, Safety Features Audits, ''The LSO shall ensure that the safety features of the laser installation facilities and laser equipment are audited periodically to assure proper operation''. The composition, frequency and rigor of that inspection/audit rests in the hands of the LSO. A common practice for institutions is to develop laser audit checklists or survey forms It is common for audit findings from one inspector or inspection to the next to vary even when reviewing the same material. How often has one heard a comment, ''well this area has been inspected several times over the years and no one ever said this or that was a problem before''. A great number of audit items, and therefore findings, are subjective because they are based on the experience and interest of the auditor to particular items on the checklist. Beam block usage, to one set of eyes might be completely adequate, while to another, inadequate. In order to provide consistency, the Laser Safety Office of the National Ignition Facility Directorate has established criteria for a number of items found on the typical laser safety audit form. The criteria are distributed to laser users. It serves two broad purposes; first, it gives the user an expectation of what will be reviewed by an auditor. Second, it is an opportunity to explain audit items to the laser user and thus the reasons for some of these items, such as labelling of beam blocks

  2. The influence of validity criteria on Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) test-retest reliability among high school athletes.

    Science.gov (United States)

    Brett, Benjamin L; Solomon, Gary S

    2017-04-01

    Research findings to date on the stability of Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) Composite scores have been inconsistent, requiring further investigation. The use of test validity criteria across these studies also has been inconsistent. Using multiple measures of stability, we examined test-retest reliability of repeated ImPACT baseline assessments in high school athletes across various validity criteria reported in previous studies. A total of 1146 high school athletes completed baseline cognitive testing using the online ImPACT test battery at two time periods of approximately two-year intervals. No participant sustained a concussion between assessments. Five forms of validity criteria used in previous test-retest studies were applied to the data, and differences in reliability were compared. Intraclass correlation coefficients (ICCs) ranged in composite scores from .47 (95% confidence interval, CI [.38, .54]) to .83 (95% CI [.81, .85]) and showed little change across a two-year interval for all five sets of validity criteria. Regression based methods (RBMs) examining the test-retest stability demonstrated a lack of significant change in composite scores across the two-year interval for all forms of validity criteria, with no cases falling outside the expected range of 90% confidence intervals. The application of more stringent validity criteria does not alter test-retest reliability, nor does it account for some of the variation observed across previously performed studies. As such, use of the ImPACT manual validity criteria should be utilized in the determination of test validity and in the individualized approach to concussion management. Potential future efforts to improve test-retest reliability are discussed.

  3. Variation in performance measure criteria significantly affects cardiology practice rankings: Insights from the National Cardiovascular Data Registry's Practice Innovation and Clinical Excellence Registry.

    Science.gov (United States)

    Eapen, Zubin J; Tang, Fengming; Jones, Phil G; Maddox, Thomas M; Oetgen, William J; Spertus, John A; Rumsfeld, John S; Heidenreich, Paul A; Peterson, Eric D; Drozda, Joseph P

    2015-06-01

    Million Hearts is a national initiative to prevent 1 million heart attacks and strokes over 5 years by improving cardiovascular prevention. An important tool in the success of programs like Million Hearts is public ranking on the quality of practices, yet different measures may provide different rankings, so the true quality of practices is difficult to discern. We evaluated the quality of ambulatory cardiology care using performance measure metrics. We compared rankings of practices participating in the National Cardiovascular Data Registry's Practice Innovation and Clinical Excellence Registry using measures from (1) the physician quality reporting system and (2) the American College of Cardiology/American Heart Association/Physician Consortium for Performance Improvement. We compared achievement rates for measures between the 2 frameworks and determined correlations in rankings using Spearman correlation coefficients. From January 1, 2008 to December 31, 2012, there were 1,711,326 patients enrolled from 111 US practices. Among eligible patients, the physician quality reporting system and American College of Cardiology/American Heart Association/Physician Consortium for Performance Improvement measures were achieved in 76.1% versus 77.4% for antiplatelet prescription (P performance and failing to achieve public health goals. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Optimization of the reversed-phase high-performance liquid chromatographic separation of synthetic estrogenic and progestogenic steroids using the multi-criteria decision making method

    NARCIS (Netherlands)

    Smilde, A. K.; Bruins, C. H.; Doornbos, D. A.; Vink, J.

    1987-01-01

    The optimization of the reversed-phase high-performance liquid chromatographic separation of a mixture of ethynylestradiol, desogestrel and three related compounds is described. A procedure is used that allows the prediction of the capacity factors of each individual synthetic steroid, depending on

  5. Biological Water Quality Criteria

    Science.gov (United States)

    Page contains links to Technical Documents pertaining to Biological Water Quality Criteria, including, technical assistance documents for states, tribes and territories, program overviews, and case studies.

  6. Functional design criteria for project W-252, phase II liquid effluent treatment and disposal. Revision 2

    International Nuclear Information System (INIS)

    Hatch, C.E.

    1995-05-01

    This document is the Functional Design Criteria for Project W-252. Project W-252 provides the scope to provide BAT/AKART (best available technology...) to 200 Liquid Effluent Phase II streams (B-Plant). This revision (Rev. 2) incorporates a major descoping of the project. The descoping was done to reflect a combination of budget cutting measures allowed by a less stringent regulatory posture toward the Phase II streams

  7. Validation of the abrasion resistance test protocols and performance criteria of EN13595: The probability of soft tissue injury to motorcycle riders by abrasion resistance of their clothing.

    Science.gov (United States)

    Meredith, Lauren; Hurren, Christopher; Clarke, Elizabeth; Fitzharris, Michael; Baldock, Matthew; de Rome, Liz; Olivier, Jake; Brown, Julie

    2017-06-01

    Motorcyclists represent an increasing proportion of road users globally and are increasingly represented in crash statistics. Soft tissue injuries are the most common type of injuries to crashed motorcyclists. These injuries can be prevented through the use of protective clothing designed for motorcycle use. However, the quality of such clothing is not controlled in many countries around the world. A European Standard was developed to assess the performance of clothing but as this is not mandatory, clothing certified to this Standard is difficult to obtain. Given the importance of this Standard, and that it has been validated only once, further validation work is required. In-depth crash investigation data were used to investigate the relationship between the abrasion resistance performance of clothing and real-world injury outcome. Clothing was collected from riders who crashed on public roads in Sydney and Newcastle, Australia. This clothing was tested according to the EU Standard and the time to hole was recorded. Hospital medical records were reviewed and the association between a rider suffering a soft tissue injury and the time-to-hole for the garment was examined. The probability of soft tissue injury for Level 1 Standard garments was between 40-60%, but more than 60% of garments tested failed to meet the minimum requirement. The findings of this study provide qualified support for the Standard, with a marginal association between time-to-hole and injury being found. This work supports the need for improved safety performance and an increased number of high performing garments being available to motorcyclists. Copyright © 2017 Elsevier Ltd and National Safety Council. All rights reserved.

  8. Weighting Performance Evaluation Criteria Base in Balanced Score Card Approach with Use of Combination Method Shapley value & Bull\\'s-eye

    Directory of Open Access Journals (Sweden)

    Mohammad Hassan Kamfiroozi

    2014-05-01

    Full Text Available Performance evaluation as a control tool was considered by managers in the organizations and manufactures. In this paper we decide to present a new model for performance evaluation and industrial companies ranking at uncertain conditions. Based on this, we implemented performance evaluation based on balance score card (BSC method. Beside, we tried to use three parameter interval grey numbers in lieu of linguistic variables. Then evaluation and weighting of fourth indicators is done with use of Bulls-eye-Shapley combination method that is counted as new approach in this article. Reason of utilization of three parameter interval grey numbers and combination method was decreasing of environmental uncertainty on data and model. This combination weighting method can be used as a new method in decision making Science. At final of this paper case study was implemented on industrial companies (nail makers that ranking of these companies is obtained by use of grey-TOPSIS method (that is a generalization of classic TOPSIS for three parameter interval grey numbers.

  9. Presentation of the EURODELTA III intercomparison exercise – evaluation of the chemistry transport models' performance on criteria pollutants and joint analysis with meteorology

    Directory of Open Access Journals (Sweden)

    B. Bessagnet

    2016-10-01

    Full Text Available The EURODELTA III exercise has facilitated a comprehensive intercomparison and evaluation of chemistry transport model performances. Participating models performed calculations for four 1-month periods in different seasons in the years 2006 to 2009, allowing the influence of different meteorological conditions on model performances to be evaluated. The exercise was performed with strict requirements for the input data, with few exceptions. As a consequence, most of differences in the outputs will be attributed to the differences in model formulations of chemical and physical processes. The models were evaluated mainly for background rural stations in Europe. The performance was assessed in terms of bias, root mean square error and correlation with respect to the concentrations of air pollutants (NO2, O3, SO2, PM10 and PM2.5, as well as key meteorological variables. Though most of meteorological parameters were prescribed, some variables like the planetary boundary layer (PBL height and the vertical diffusion coefficient were derived in the model preprocessors and can partly explain the spread in model results. In general, the daytime PBL height is underestimated by all models. The largest variability of predicted PBL is observed over the ocean and seas. For ozone, this study shows the importance of proper boundary conditions for accurate model calculations and then on the regime of the gas and particle chemistry. The models show similar and quite good performance for nitrogen dioxide, whereas they struggle to accurately reproduce measured sulfur dioxide concentrations (for which the agreement with observations is the poorest. In general, the models provide a close-to-observations map of particulate matter (PM2.5 and PM10 concentrations over Europe rather with correlations in the range 0.4–0.7 and a systematic underestimation reaching −10 µg m−3 for PM10. The highest concentrations are much more underestimated, particularly in

  10. Rethinking Dental School Admission Criteria: Correlation Between Pre-Admission Variables and First-Year Performance for Six Classes at One Dental School.

    Science.gov (United States)

    Rowland, Kevin C; Rieken, Susan

    2018-04-01

    Admissions committees in dental schools are charged with the responsibility of selecting candidates who will succeed in school and become successful members of the profession. Identifying students who will have academic difficulty is challenging. The aim of this study was to determine the predictive value of pre-admission variables for the first-year performance of six classes at one U.S. dental school. The authors hypothesized that the variables undergraduate grade point average (GPA), undergraduate science GPA (biology, chemistry, and physics), and Dental Admission Test (DAT) scores would predict the level of performance achieved in the first year of dental school, measured by year-end GPA. Data were collected in 2015 from school records for all 297 students in the six cohorts who completed the first year (Classes of 2007 through 2013). In the results, statistically significant correlations existed between all pre-admission variables and first-year GPA, but the associations were only weak to moderate. Lower performing students at the end of the first year (lowest 10% of GPA) had, on average, lower pre-admission variables than the other students, but the differences were small (≤10.8% in all categories). When all the pre-admission variables were considered together in a multiple regression analysis, a significant association was found between pre-admission variables and first-year GPA, but the association was weak (adjusted R 2 =0.238). This weak association suggests that these students' first-year dental school GPAs were mostly determined by factors other than the pre-admission variables studied and has resulted in the school's placing greater emphasis on other factors for admission decisions.

  11. Stormwater Tank Performance: Design and Management Criteria for Capture Tanks Using a Continuous Simulation and a Semi-Probabilistic Analytical Approach

    Directory of Open Access Journals (Sweden)

    Flavio De Martino

    2013-10-01

    Full Text Available Stormwater tank performance significantly depends on management practices. This paper proposes a procedure to assess tank efficiency in terms of volume and pollutant concentration using four different capture tank management protocols. The comparison of the efficiency results reveals that, as expected, a combined bypass—stormwater tank system achieves better results than a tank alone. The management practices tested for the tank-only systems provide notably different efficiency results. The practice of immediately emptying after the end of the event exhibits significant levels of efficiency and operational advantages. All other configurations exhibit either significant operational problems or very low performances. The continuous simulation and semi-probabilistic approach for the best tank management practice are compared. The semi-probabilistic approach is based on a Weibull probabilistic model of the main characteristics of the rainfall process. Following this approach, efficiency indexes were established. The comparison with continuous simulations shows the reliability of the probabilistic approach even if this last is certainly very site sensitive.

  12. Perspectives on the revised Ghent criteria for the diagnosis of Marfan syndrome

    Directory of Open Access Journals (Sweden)

    von Kodolitsch Y

    2015-06-01

    Full Text Available Yskert von Kodolitsch,1 Julie De Backer,2 Helke Schüler,1 Peter Bannas,3 Cyrus Behzadi,3 Alexander M Bernhardt,1 Mathias Hillebrand,1 Bettina Fuisting,4 Sara Sheikhzadeh,1 Meike Rybczynski,1 Tilo Kölbel,1 Klaus Püschel,5 Stefan Blankenberg,1 Peter N Robinson61Centre of Cardiology, University Hospital Eppendorf, Hamburg, Germany; 2Centre for Medical Genetics, University Hospital Ghent, Ghent, Belgium; 3Diagnostic and Interventional Radiology Department and Clinic, 4Department of Ophthalmology, 5Department of Legal Medicine, University Hospital Eppendorf, Hamburg, Germany; 6Institute of Medical Genetics and Human Genetics, Charité Universitätsmedizin, Berlin, Germany Abstract: Three international nosologies have been proposed for the diagnosis of Marfan syndrome (MFS: the Berlin nosology in 1988; the Ghent nosology in 1996 (Ghent-1; and the revised Ghent nosology in 2010 (Ghent-2. We reviewed the literature and discussed the challenges and concepts of diagnosing MFS in adults. Ghent-1 proposed more stringent clinical criteria, which led to the confirmation of MFS in only 32%–53% of patients formerly diagnosed with MFS according to the Berlin nosology. Conversely, both the Ghent-1 and Ghent-2 nosologies diagnosed MFS, and both yielded similar frequencies of MFS in persons with a causative FBN1 mutation (90% for Ghent-1 versus 92% for Ghent-2 and in persons not having a causative FBN1 mutation (15% versus 13%. Quality criteria for diagnostic methods include objectivity, reliability, and validity. However, the nosology-based diagnosis of MFS lacks a diagnostic reference standard and, hence, quality criteria such as sensitivity, specificity, or accuracy cannot be assessed. Medical utility of diagnosis implies congruency with the historical criteria of MFS, as well as with information about the etiology, pathogenesis, diagnostic triggers, prognostic triggers, and potential complications of MFS. In addition, social and psychological utilities of

  13. Dual Criteria Decisions

    DEFF Research Database (Denmark)

    Andersen, Steffen; Harrison, Glenn W.; Lau, Morten Igel

    2014-01-01

    The most popular models of decision making use a single criterion to evaluate projects or lotteries. However, decision makers may actually consider multiple criteria when evaluating projects. We consider a dual criteria model from psychology. This model integrates the familiar tradeoffs between...

  14. VALIDATION OF ANSI N42.34 AMERICAN NATIONAL STANDARD PERFORMANCE CRITERIA FOR HAND-HELD INSTRUMENTS FOR THE DETECTION AND IDENTIFICATION OF RADIONUCLIDES

    Energy Technology Data Exchange (ETDEWEB)

    Lorier, T.

    2014-09-03

    SRNL’s validation of ANSI N42.34-D6 for the Domestic Nuclear Detection Office (DNDO) was performed utilizing one hand-held instrument (or RID) – the FLIR identiFINDER 2. Each section of the standard was evaluated via a walk-through or test. NOTE: In Table 1, W = walk-through and T = test, as directed by the Domestic Nuclear Detection Office (DNDO). For a walk-through, the experiment was either setup or reviewed for setup; for a test, the N42.34-D6 procedures were followed with some exceptions and comments noted. SRNL is not fully able to evaluate a RID against Sections 7 (Environmental), 8 (Electromagnetic), and 9 (Mechanical) of N42.34, so those portions of this validation were done in collaboration with Qualtest, Inc. in Orlando, Florida. The walk-throughs and tests of Sections 7, 8, and 9 were performed in Qualtest, Inc. facilities with SRNL providing radiological sources as necessary. Where applicable, assessment results and findings of the walk-throughs and tests were recorded on datasheets and a validation summary is provided. A general comment pertained to test requirements found in another standard and referenced in N42.34-D6. For example, step 1 of the test method in section 8.1.2 states “RF test set up information can be found in IEC 61000-4-3.” It is recommended that any information from other standards necessary for conducting the tests within N42.34 should be posted in N42.34 for simplicity and to prevent the user from having to peruse other documents. Another general comment, as noted by Qualtest, is that a tolerance reference is not listed for each test in sections 7-9. Overall, the N42.34-D6 was proven to be practicable, but areas for improvement and recommendations were identified for consideration prior to final ballot submittal.

  15. FHR Generic Design Criteria

    Energy Technology Data Exchange (ETDEWEB)

    Flanagan, G.F.; Holcomb, D.E.; Cetiner, S.M.

    2012-06-15

    The purpose of this document is to provide an initial, focused reference to the safety characteristics of and a licensing approach for Fluoride-Salt-Cooled High-Temperature Reactors (FHRs). The document does not contain details of particular reactor designs nor does it attempt to identify or classify either design basis or beyond design basis accidents. Further, this document is an initial attempt by a small set of subject matter experts to document the safety and licensing characteristics of FHRs for a larger audience. The document is intended to help in setting the safety and licensing research, development, and demonstration path forward. Input from a wider audience, further technical developments, and additional study will be required to develop a consensus position on the safety and licensing characteristics of FHRs. This document begins with a brief overview of the attributes of FHRs and then a general description of their anticipated safety performance. Following this, an overview of the US nuclear power plant approval process is provided that includes both test and power reactors, as well as the role of safety standards in the approval process. The document next describes a General Design Criteria (GDC)–based approach to licensing an FHR and provides an initial draft set of FHR GDCs. The document concludes with a description of a path forward toward developing an FHR safety standard that can support both a test and power reactor licensing process.

  16. FHR Generic Design Criteria

    Energy Technology Data Exchange (ETDEWEB)

    Flanagan, George F [ORNL; Holcomb, David Eugene [ORNL; Cetiner, Sacit M [ORNL

    2012-06-01

    The purpose of this document is to provide an initial, focused reference to the safety characteristics of and a licensing approach for Fluoride-Salt-Cooled High-Temperature Reactors (FHRs). The document does not contain details of particular reactor designs nor does it attempt to identify or classify either design basis or beyond design basis accidents. Further, this document is an initial attempt by a small set of subject matter experts to document the safety and licensing characteristics of FHRs for a larger audience. The document is intended to help in setting the safety and licensing research, development, and demonstration path forward. Input from a wider audience, further technical developments, and additional study will be required to develop a consensus position on the safety and licensing characteristics of FHRs. This document begins with a brief overview of the attributes of FHRs and then a general description of their anticipated safety performance. Following this, an overview of the US nuclear power plant approval process is provided that includes both test and power reactors, as well as the role of safety standards in the approval process. The document next describes a General Design Criteria (GDC) - based approach to licensing an FHR and provides an initial draft set of FHR GDCs. The document concludes with a description of a path forward toward developing an FHR safety standard that can support both a test and power reactor licensing process.

  17. Stringent and reproducible tetracycline-regulated transgene expression by site-specific insertion at chromosomal loci with pre-characterised induction characteristics

    Directory of Open Access Journals (Sweden)

    Papanastasiou Antigoni M

    2007-05-01

    Full Text Available Abstract Background The ability to regulate transgene expression has many applications, mostly concerning the analysis of gene function. Desirable induction characteristics, such as low un-induced expression, high induced expression and limited cellular heterogeneity, can be seriously impaired by chromosomal position effects at the site of transgene integration. Many clones may therefore need to be screened before one with optimal induction characteristics is identified. Furthermore, such screens must be repeated for each new transgene investigated, and comparisons between clones with different transgenes is complicated by their different integration sites. Results To circumvent these problems we have developed a "screen and insert" strategy in which clones carrying a transgene for a fluorescent reporter are first screened for those with optimal induction characteristics. Site-specific recombination (SSR is then be used repeatedly to insert any new transgene at the reporter transgene locus of such clones so that optimal induction characteristics are conferred upon it. Here we have tested in a human fibrosarcoma cell line (HT1080 two of many possible implementations of this approach. Clones (e.g. Rht14-10 in which a GFP reporter gene is very stringently regulated by the tetracycline (tet transactivator (tTA protein were first identified flow-cytometrically. Transgenes encoding luciferase, I-SceI endonuclease or Rad52 were then inserted by SSR at a LoxP site adjacent to the GFP gene resulting stringent tet-regulated transgene expression. In clone Rht14-10, increases in expression from essentially background levels (+tet to more than 104-fold above background (-tet were reproducibly detected after Cre-mediated insertion of either the luciferase or the I-SceI transgenes. Conclusion Although previous methods have made use of SSR to integrate transgenes at defined sites, none has effectively combined this with a pre-selection step to identify

  18. On approximating multi-criteria TSP

    NARCIS (Netherlands)

    Manthey, Bodo; Albers, S.; Marion, J.-Y.

    2009-01-01

    We present approximation algorithms for almost all variants of the multi-criteria traveling salesman problem (TSP), whose performances are independent of the number $k$ of criteria and come close to the approximation ratios obtained for TSP with a single objective function. We present randomized

  19. 45 CFR 1801.21 - Evaluation criteria.

    Science.gov (United States)

    2010-10-01

    ...) Academic performance and writing and analytical skills; and (4) Suitability of the nominee's proposed... 45 Public Welfare 4 2010-10-01 2010-10-01 false Evaluation criteria. 1801.21 Section 1801.21... HARRY S. TRUMAN SCHOLARSHIP PROGRAM The Competition § 1801.21 Evaluation criteria. (a) The Foundation...

  20. Historic and future trends of vehicle emissions in Beijing, 1998-2020: A policy assessment for the most stringent vehicle emission control program in China

    Science.gov (United States)

    Zhang, Shaojun; Wu, Ye; Wu, Xiaomeng; Li, Mengliang; Ge, Yunshan; Liang, Bin; Xu, Yueyun; Zhou, Yu; Liu, Huan; Fu, Lixin; Hao, Jiming

    2014-06-01

    As a pioneer in controlling vehicle emissions within China, Beijing released the Clean Air Action Plan 2013-2017 document in August 2013 to improve its urban air quality. It has put forward this plan containing the most stringent emission control policies and strategies to be adopted for on-road vehicles of Beijing. This paper estimates the historic and future trends and uncertainties in vehicle emissions of Beijing from 1998 to 2020 by applying a new emission factor model for the Beijing vehicle fleet (EMBEV). Our updated results show that total emissions of CO, THC, NOx and PM2.5 from the Beijing vehicle fleet are 507 (395-819) kt, 59.1 (41.2-90.5) kt, 74.7 (54.9-103.9) kt and 2.69 (1.91-4.17) kt, respectively, at a 95% confidence level. This represents significant reductions of 58%, 59%, 31% and 62%, respectively, relative to the total vehicle emissions in 1998. The past trends clearly posed a challenge to NOx emission mitigation for the Beijing vehicle fleet, especially in light of those increasing NOx emissions from heavy-duty diesel vehicles (HDDVs) which have partly offset the reduction benefit from light-duty gasoline vehicles (LDGVs). Because of recently announced vehicle emission controls to be adopted in Beijing, including tighter emissions standards, limitations on vehicle growth by more stringent license control, promotion of alternative fuel technologies (e.g., natural gas) and the scrappage of older vehicles, estimated vehicle emissions in Beijing will continue to be mitigated by 74% of CO, 68% of THC, 56% of NOx and 72% of PM2.5 in 2020 compared to 2010 levels. Considering that many of the megacities in China are facing tremendous pressures to mitigate emissions from on-road vehicles, our assessment will provide a timely case study of significance for policy-makers in China.

  1. Risk based seismic design criteria

    International Nuclear Information System (INIS)

    Kennedy, R.P.

    1999-01-01

    In order to develop a risk based seismic design criteria the following four issues must be addressed: (1) What target annual probability of seismic induced unacceptable performance is acceptable? (2) What minimum seismic margin is acceptable? (3) Given the decisions made under Issues 1 and 2, at what annual frequency of exceedance should the safe-shutdown-earthquake (SSE) ground motion be defined? (4) What seismic design criteria should be established to reasonably achieve the seismic margin defined under Issue 2? The first issue is purely a policy decision and is not addressed in this paper. Each of the other three issues are addressed. Issues 2 and 3 are integrally tied together so that a very large number of possible combinations of responses to these two issues can be used to achieve the target goal defined under Issue 1. Section 2 lays out a combined approach to these two issues and presents three potentially attractive combined resolutions of these two issues which reasonably achieves the target goal. The remainder of the paper discusses an approach which can be used to develop seismic design criteria aimed at achieving the desired seismic margin defined in resolution of Issue 2. Suggestions for revising existing seismic design criteria to more consistently achieve the desired seismic margin are presented. (orig.)

  2. Water Quality Criteria

    Science.gov (United States)

    EPA develops water quality criteria based on the latest scientific knowledge to protect human health and aquatic life. This information serves as guidance to states and tribes in adopting water quality standards.

  3. Aquatic Life Criteria - Atrazine

    Science.gov (United States)

    Documents pertaining to Acute and Chronic Ambient Water Quality Aquatic Life Criteria for Atrazine (Freshwater and Salt Water). This document contains the safe levels of Atrazine in water that should protect to the majority of species.

  4. Aquatic Life Criteria - Copper

    Science.gov (United States)

    Documents pertain to Aquatic Life Ambient Water Quality criteria for Copper (2007 Freshwater, 2016 Estuarine/marine). These documents contain the safe levels of Copper in water that should protect to the majority of species.

  5. Aquatic Life Criteria - Ammonia

    Science.gov (United States)

    Documents related to EPA's final 2013 Aquatic Life Ambient Water Quality Criteria for Ammonia (Freshwater). These documents pertain to the safe levels of Ammonia in water that should protect to the majority of species.

  6. Criteria Air Emissions Trends

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Air Emissions Trends site provides national trends of criteria pollutant and precursor emissions data based on the the National Emissions Inventory (NEI) from...

  7. Multimodal freight investment criteria.

    Science.gov (United States)

    2010-07-01

    Literature was reviewed on multi-modal investment criteria for freight projects, examining measures and techniques for quantifying project benefits and costs, as well as ways to describe the economic importance of freight transportation. : A limited ...

  8. Aquatic Life Criteria - Cadmium

    Science.gov (United States)

    Documents pertaining to 2016 Acute and Chronic Aquatic Life Ambient Water Quality Criteria for Cadmium (Freshwater, Estuarine/marine). These documents contain the safe levels of Cadmium in water that should protect to the majority of species.

  9. Criteria for Evaluating the Performance of Compilers

    Science.gov (United States)

    1974-10-01

    value of ease oZ use factors can then be added into the anaiyais in a straightforward manner. To apply this approach therefore requires research (beyond...used in commercially available compilers, or which are currently being investigated in various research environments. Each of these optimization...r- Statement. E fcrm in FOR Statement. 3. F form in FOR Statement,I, G form in FOR Statement. 5. X form in FOR Staterent . 6. X form in IF Statement

  10. 24 CFR 214.303 - Performance criteria.

    Science.gov (United States)

    2010-04-01

    ... mortgage lenders, brokers, builders, or real estate sales agents or brokers in which the officer, employee... referring a client to mortgage lenders, brokers, builders, or real estate sales agents or brokers. (3) A...) Conflicts of interest. (1) A director, employee, officer, contractor, or agent of a participating agency...

  11. Leadership Criteria under Maximum Performance Conditions

    Science.gov (United States)

    2011-03-01

    metacognitive prompting) due to cross loading once results less than .4 were suppressed. Thus, upon further analysis of the SOS 31 factors, factor 1...to cross loading as mentioned previously (i.e. honesty and metacognitive prompting). A discussion of the SOS factors is presented. In the AIB...Reciprocal effects of teacher behavior and student engagement across the school year. Journal of Educational Psychology, 85(4), 571. Society for

  12. Summarized water quality criteria

    International Nuclear Information System (INIS)

    Kempster, P.L.; Hattingh, W.H.J.; Van Vliet, H.R.

    1980-08-01

    The available world literature from 27 sources on existing water quality criteria are summarized for the 15 main uses of water. The minimum, median and maximum specified values for 96 different determinands are included. Under each water use the criteria are grouped according to the functional significance of the determinands e.g. aesthetic/physical effects, high toxic potential, low toxic potential etc. A synopsis is included summarizing salient facts for each determinand such as the conditions under which it is toxic and its relationship to other determinands. The significance of the criteria is briefly discussed and the importance of considering functional interactions between determinands emphasized in evaluating the potential for toxic or beneficial effects. From the source literature it appears that the toxic potential, in addition to being determined by concentration, is also affected by the origin of the substance concerned, i.e. whether from natural sources or from anthropogenic pollution

  13. Effectiveness of cleanup criteria relative to an accidental nuclear release

    International Nuclear Information System (INIS)

    Chen, S.Y.; Yuan, Y.C.

    1988-01-01

    In the event of an accidental nuclear release, the associated long-term radiological risks would result primarily from ground contamination pathways. Cleanup of the contaminated ground surfaces is a necessary step toward reducing the radiological risk to the general population. Ideally, the radiological risk decreases as the level of cleanup effort increases; however, as the cleanup criterion (i.e., the required contaminant concentration after cleanup) becomes more stringent, the cleanup effort may become prohibitively costly. This study examines several factors that are important in determining the effectiveness of the cleanup criteria for selected radionuclides: (a) annual individual dose commitment (mrem/yr), (b) total population environmental dose commitment (person-rem), and (c) total area (km 2 ) requiring cleanup following an accident. To effectively protect the general population, the benefits of cleanup should be weighed against the potentially large increase in cleanup area (and the associated costs) as the cleanup criterion becomes more stringent. The effectiveness of cleanup will vary, depending largely on site-specific parameters such as population density and agricultural productivity as well as on the amount and type of radionuclide released. Determination of an optimum cleanup criterion should account for all factors, including a comprehensive cost/benefit analysis

  14. Genetic Algorithms to Optimizatize Lecturer Assessment's Criteria

    Science.gov (United States)

    Jollyta, Deny; Johan; Hajjah, Alyauma

    2017-12-01

    The lecturer assessment criteria is used as a measurement of the lecturer's performance in a college environment. To determine the value for a criteriais complicated and often leads to doubt. The absence of a standard valuefor each assessment criteria will affect the final results of the assessment and become less presentational data for the leader of college in taking various policies relate to reward and punishment. The Genetic Algorithm comes as an algorithm capable of solving non-linear problems. Using chromosomes in the random initial population, one of the presentations is binary, evaluates the fitness function and uses crossover genetic operator and mutation to obtain the desired crossbreed. It aims to obtain the most optimum criteria values in terms of the fitness function of each chromosome. The training results show that Genetic Algorithm able to produce the optimal values of lecturer assessment criteria so that can be usedby the college as a standard value for lecturer assessment criteria.

  15. Radiological design criteria

    International Nuclear Information System (INIS)

    Selby, J.M.; Andersen, B.V.; Carter, L.A.; Waite, D.A.

    1977-01-01

    Many new nuclear facilities are unsatisfactory from a radiation protection point of view, particularly when striving to maintain occupational exposure as low as practicable 'ALAP'. Radiation protection is achieved through physical protective features supplemented by administrative controls. Adequate physical protective feature should be achieved during construction so that supplemental administrative controls may be kept simple and workable. Many nuclear facilities fall short of adequate physical protective features, thus, remedial and sometimes awkward administrative procedures are required to safely conduct work. In reviewing the various handbooks, reports and regulations which deal with radiation protection, it may be noted that there is minimal radiological design guidance for application to nuclear facilities. A set of criteria or codes covering functional areas rather than specific nuclear facility types is badly needed. The following are suggested as functional areas to be considered: characterization of the Facility; siting and access; design exposure limits; layout (people and materials flow); ventilation and effluent control; radiation protection facilities and systems. The application of such radiological design criteria early in the design process would provide some assurance that nuclear facilities will be safe, flexible, and efficient with a minimum of costly retrofitting or administrative restrictions. Criteria which we have found helpful in these functional areas is discussed together with justification for adoption of such criteria and identification of problems which still require solution

  16. Comments on confinement criteria

    International Nuclear Information System (INIS)

    Kurak, V.; Schroer, B.; Swieca, J.A.

    1977-01-01

    For a QED 2 model with SU(n) flavour, the nature of the physical states space is more subtle than one expects on the basis of the loop criterion for confinement. One may have colour confinement without confinement of the fundamental flavour representation. Attempts to formulate confinement criteria in which the quark fields play a more fundamental role are discussed [pt

  17. Redefining design criteria for Pu-238 gloveboxes

    International Nuclear Information System (INIS)

    Acosta, S.V.

    1998-01-01

    Enclosures for confinement of special nuclear materials (SNM) have evolved into the design of gloveboxes. During the early stages of glovebox technology, established practices and process operation requirements defined design criteria. Proven boxes that performed and met or exceeded process requirements in one group or area, often could not be duplicated in other areas or processes, and till achieve the same success. Changes in materials, fabrication and installation methods often only met immediate design criteria. Standardization of design criteria took a big step during creation of ''Special-Nuclear Materials R and D Laboratory Project, Glovebox standards''. The standards defined design criteria for every type of process equipment in its most general form. Los Alamos National Laboratory (LANL) then and now has had great success with Pu-238 processing. However with ever changing Environment Safety and Health (ES and H) requirements and Ta-55 Facility Configuration Management, current design criteria are forced to explore alternative methods of glovebox design fabrication and installation. Pu-238 fuel processing operations in the Power Source Technologies Group have pushed the limitations of current design criteria. More than half of Pu-238 gloveboxes are being retrofitted or replaced to perform the specific fuel process operations. Pu-238 glovebox design criteria are headed toward process designed single use glovebox and supporting line gloveboxes. Gloveboxes that will house equipment and processes will support TA-55 Pu-238 fuel processing needs into the next century and extend glovebox expected design life

  18. Kütüphanelerde Performans Ölçümü: IFLA Performans Ölçütlerinin Değerlendirilmesi = Performance Measurement in Libraries: Evaluation of IFLA Performance Measurement Criteria

    Directory of Open Access Journals (Sweden)

    Yıldız, Asiye Kakırman

    2010-04-01

    Full Text Available Bu çalışmada, IFLA tarafından 1996 yılında ilk baskısı yapılan "Akademik Kütüphanelerde Performans Ölçümü" adlı kitabın, 2007 yılında gözden geçirilerek ikinci baskısının "Kütüphanelerde Performans Ölçümü" adı altında yapılmasının nedenleri ve bu iki baskının karşılaştırmalı bir değerlendirmesi yapılmıştır. Aradan geçen 11 yıllık süre içerisinde meydana gelen değişimlerin, kütüphanelerin performansını değerlendirmek için kullanılan ölçütlerde nasıl değişiklik yarattığı görülecek ve bu kitaplar çerçevesinde, yaşanan değişimlerin kütüphanelere olan etkisi tartışılacaktır. This study consists of a comparative analysis of the reasons that led to the production of two diff erent editions of the book "Performance Measurement in Libraries" (2007, which had previously been published as "Performance Measurement in Academic Libraries" in 1996. This study will discuss the innovations and changes that took place during the eleven years between two editions and their impacts on the performance evaluation of libraries.

  19. TAPS safety evaluation criteria for reload fueling

    International Nuclear Information System (INIS)

    Mahendra Nath; Veeraraghavan, N.

    1976-01-01

    To improve operating performance of Tarapur reactors, several proposals are under consideration such as core expansion, change-over to an improved fuel design with lower heat rating, extension of fuel cycle lengths etc., which have a bearing on overall plant operating characteristics and reactor safety. For evaluating safety implications of the various proposals, it is necessary to formulate safety evaluation criteria for reload fuelling. Salient features of these criteria are discussed. (author)

  20. İnovasyon Süreci Performansı Ölçüm Kriterlerini Nitel Bir Araştırma İle Belirleme: Bilişim Sektöründen Bulgular - Defining Innovation Process Performance Measurement Criteria with a Qualitative Research: Findings from IT Sector

    Directory of Open Access Journals (Sweden)

    Yunus Emre TAŞGİT

    2016-06-01

    Full Text Available The aim of this study is to define innovation performance measurement criteria for firms and measure their performance through these criteria. IT firms in technoparks at TR42 East Marmara Region are included in the study and qualitative research method is used. Data are collected through the interviews conducted with managers of IT firms and are analyzed with descriptive and content analysis techniques. After the analysis, some measurement criteria are introduced to measure the innovation performance. Results show that “Idea Generation” stage is not taken seriously by these firms. Performances of “Beta Version Development” and “Full Version Development” stages are high. Firms have to analyze “Sale” stage carefully.

  1. Human Systems Design Criteria

    DEFF Research Database (Denmark)

    Rasmussen, Jens

    1982-01-01

    This paper deals with the problem of designing more humanised computer systems. This problem can be formally described as the need for defining human design criteria, which — if used in the design process - will secure that the systems designed get the relevant qualities. That is not only...... the necessary functional qualities but also the needed human qualities. The author's main argument is, that the design process should be a dialectical synthesis of the two points of view: Man as a System Component, and System as Man's Environment. Based on a man's presentation of the state of the art a set...... of design criteria is suggested and their relevance discussed. The point is to focus on the operator rather than on the computer. The crucial question is not to program the computer to work on its own conditions, but to “program” the operator to function on human conditions....

  2. Intelligent intefrace design criteria

    International Nuclear Information System (INIS)

    Sicard, Y.; Siebert, S.; Thebault, M.H.

    1990-01-01

    Optimum adequation between control means and the capacities of the teams of operators is sought for to achieve computerization of control and monitoring interfaces. Observation of the diagnosis activity of populations of operators in incident situations on a simulator enables design criteria well-suited to the characteristics of the detection, interpretation of symptoms and incident location tasks to be defined. A software tool based on a qualitative approach enables the design process to be systematized

  3. 24 CFR 594.17 - General criteria for competitive selection.

    Science.gov (United States)

    2010-04-01

    ... selection. 594.17 Section 594.17 Housing and Urban Development Regulations Relating to Housing and Urban... Allocation and Criteria § 594.17 General criteria for competitive selection. (a) Criteria. HUD will use the... neighborhood; (2) The past performance in carrying out eligible activities, and staff capability; (3) The...

  4. Structural acceptance criteria Remote Handling Building Tritium Extraction Facility

    International Nuclear Information System (INIS)

    Mertz, G.

    1999-01-01

    This structural acceptance criteria contains the requirements for the structural analysis and design of the Remote Handling Building (RHB) in the Tritium Extraction Facility (TEF). The purpose of this acceptance criteria is to identify the specific criteria and methods that will ensure a structurally robust building that will safely perform its intended function and comply with the applicable Department of Energy (DOE) structural requirements

  5. Reflection on the efficiency criteria for a long duration disposal with respect to temporary abandonment situations; Reflexion sur les criteres de performance d'un entreposage de longue duree (ELD) vis-a-vis des situations de delaissement temporaire

    Energy Technology Data Exchange (ETDEWEB)

    Heriard-Dubreuil, G.; Gadbois, S. [Mutadis, 75 - Paris (France); Chieber, C.; Schneider, Th. [Centre d' Etude sur l' Evaluation de la Protection dans le Domaine Nucleaire, 92 - Fontenay aux Roses (France)

    2002-08-15

    A study carried out by Mutadis and CEPN, on request of the CEA, aimed at supplying some elements allowing to elaborate some performance criteria for a long-term management system in front of situations of temporary abandonment of radioactive waste disposal facilities. The first part of the study has been the identification of case studies illustrating situations of loss of maintenance or temporary abandonment. The second phase has been the selection and analysis of 4 case studies (the ancient underground cavities in Ile-de-France, the regulation relative to new underground quarries, the abandoned mines in Loraine basin, and Unesco's approach for the protection of mankind world patrimony). These cases have been analysed with respect to various aspects: actors involved, construction management and memory preservation, liabilities in time and space, prevention means, scheduling, and resumption strategies. The concepts of abandonment, scheduling and resumption have been precised and analysed in a third part according to the case studies. Three goals - avoiding abandonment, encouraging scheduling and resumption - and eight characteristics are drawn from this analysis, which are indicators of the robustness of the system implemented to fulfill these 3 goals. These characteristics appear as strongly interdependent. (J.S.)

  6. WARM JUPITERS NEED CLOSE ''FRIENDS'' FOR HIGH-ECCENTRICITY MIGRATION—A STRINGENT UPPER LIMIT ON THE PERTURBER'S SEPARATION

    Energy Technology Data Exchange (ETDEWEB)

    Dong, Subo [Kavli Institute for Astronomy and Astrophysics, Peking University, Yi He Yuan Road 5, Hai Dian District, Beijing 100871 (China); Katz, Boaz; Socrates, Aristotle [Institute for Advanced Study, 1 Einstein Dr., Princeton, NJ 08540 (United States)

    2014-01-20

    We propose a stringent observational test on the formation of warm Jupiters (gas-giant planets with 10 days ≲ P ≲ 100 days) by high-eccentricity (high-e) migration mechanisms. Unlike hot Jupiters, the majority of observed warm Jupiters have pericenter distances too large to allow efficient tidal dissipation to induce migration. To access the close pericenter required for migration during a Kozai-Lidov cycle, they must be accompanied by a strong enough perturber to overcome the precession caused by general relativity, placing a strong upper limit on the perturber's separation. For a warm Jupiter at a ∼ 0.2 AU, a Jupiter-mass (solar-mass) perturber is required to be ≲ 3 AU (≲ 30 AU) and can be identified observationally. Among warm Jupiters detected by radial velocities (RVs), ≳ 50% (5 out of 9) with large eccentricities (e ≳ 0.4) have known Jovian companions satisfying this necessary condition for high-e migration. In contrast, ≲ 20% (3 out of 17) of the low-e (e ≲ 0.2) warm Jupiters have detected additional Jovian companions, suggesting that high-e migration with planetary perturbers may not be the dominant formation channel. Complete, long-term RV follow-ups of the warm-Jupiter population will allow a firm upper limit to be put on the fraction of these planets formed by high-e migration. Transiting warm Jupiters showing spin-orbit misalignments will be interesting to apply our test. If the misalignments are solely due to high-e migration as commonly suggested, we expect that the majority of warm Jupiters with low-e (e ≲ 0.2) are not misaligned, in contrast with low-e hot Jupiters.

  7. Inducible Expression of Agrobacterium Virulence Gene VirE2 for Stringent Regulation of T-DNA Transfer in Plant Transient Expression Systems.

    Science.gov (United States)

    Denkovskienė, Erna; Paškevičius, Šarūnas; Werner, Stefan; Gleba, Yuri; Ražanskienė, Aušra

    2015-11-01

    Agrotransfection with viral vectors is an effective solution for the transient production of valuable proteins in plants grown in contained facilities. Transfection methods suitable for field applications are desirable for the production of high-volume products and for the transient molecular reprogramming of plants. The use of genetically modified (GM) Agrobacterium strains for plant transfections faces substantial biosafety issues. The environmental biosafety of GM Agrobacterium strains could be improved by regulating their T-DNA transfer via chemically inducible expression of virE2, one of the essential Agrobacterium virulence genes. In order to identify strong and stringently regulated promoters in Agrobacterium strains, we evaluated isopropyl-β-d-thiogalactoside-inducible promoters Plac, Ptac, PT7/lacO, and PT5/lacOlacO and cumic acid-inducible promoters PlacUV5/CuO, Ptac/CuO, PT5/CuO, and PvirE/CuO. Nicotiana benthamiana plants were transfected with a virE2-deficient A. tumefaciens strain containing transient expression vectors harboring inducible virE2 expression cassettes and containing a marker green fluorescent protein (GFP) gene in their T-DNA region. Evaluation of T-DNA transfer was achieved by counting GFP expression foci on plant leaves. The virE2 expression from cumic acid-induced promoters resulted in 47 to 72% of wild-type T-DNA transfer. Here, we present efficient and tightly regulated promoters for gene expression in A. tumefaciens and a novel approach to address environmental biosafety concerns in agrobiotechnology.

  8. Web site Evaluation Criteria

    Directory of Open Access Journals (Sweden)

    Mojdgan binesh

    2008-07-01

    Full Text Available The ever-increasing evolution of the Internet and the growing number of the resources accessible through this medium, has turned the issue of resource evaluation of the internet-based information into a controversial and cogent issue. By nature, the internet milieu is uncontrollable. It concomitantly contains both verifiable and unverifiable information. Thus it behooves the internet users to develop resource evaluation and critical thinking skills in order to discern appropriate quality resources. Through review and comparison of the available checklists, the present paper endeavors to offer criteria for website evaluation

  9. Generalized Lawson Criteria for Inertial Confinement Fusion

    Energy Technology Data Exchange (ETDEWEB)

    Tipton, Robert E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-08-27

    The Lawson Criterion was proposed by John D. Lawson in 1955 as a general measure of the conditions necessary for a magnetic fusion device to reach thermonuclear ignition. Over the years, similar ignition criteria have been proposed which would be suitable for Inertial Confinement Fusion (ICF) designs. This paper will compare and contrast several ICF ignition criteria based on Lawson’s original ideas. Both analytical and numerical results will be presented which will demonstrate that although the various criteria differ in some details, they are closely related and perform similarly as ignition criteria. A simple approximation will also be presented which allows the inference of each ignition parameter directly from the measured data taken on most shots fired at the National Ignition Facility (NIF) with a minimum reliance on computer simulations. Evidence will be presented which indicates that the experimentally inferred ignition parameters on the best NIF shots are very close to the ignition threshold.

  10. Safety and reliability criteria

    International Nuclear Information System (INIS)

    O'Neil, R.

    1978-01-01

    Nuclear power plants and, in particular, reactor pressure boundary components have unique reliability requirements, in that usually no significant redundancy is possible, and a single failure can give rise to possible widespread core damage and fission product release. Reliability may be required for availability or safety reasons, but in the case of the pressure boundary and certain other systems safety may dominate. Possible Safety and Reliability (S and R) criteria are proposed which would produce acceptable reactor design. Without some S and R requirement the designer has no way of knowing how far he must go in analysing his system or component, or whether his proposed solution is likely to gain acceptance. The paper shows how reliability targets for given components and systems can be individually considered against the derived S and R criteria at the design and construction stage. Since in the case of nuclear pressure boundary components there is often very little direct experience on which to base reliability studies, relevant non-nuclear experience is examined. (author)

  11. Criteria to Extract High-Quality Protein Data Bank Subsets for Structure Users.

    Science.gov (United States)

    Carugo, Oliviero; Djinović-Carugo, Kristina

    2016-01-01

    It is often necessary to build subsets of the Protein Data Bank to extract structural trends and average values. For this purpose it is mandatory that the subsets are non-redundant and of high quality. The first problem can be solved relatively easily at the sequence level or at the structural level. The second, on the contrary, needs special attention. It is not sufficient, in fact, to consider the crystallographic resolution and other feature must be taken into account: the absence of strings of residues from the electron density maps and from the files deposited in the Protein Data Bank; the B-factor values; the appropriate validation of the structural models; the quality of the electron density maps, which is not uniform; and the temperature of the diffraction experiments. More stringent criteria produce smaller subsets, which can be enlarged with more tolerant selection criteria. The incessant growth of the Protein Data Bank and especially of the number of high-resolution structures is allowing the use of more stringent selection criteria, with a consequent improvement of the quality of the subsets of the Protein Data Bank.

  12. National Recommended Water Quality Criteria

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Recommended Water Quality Criteria is a compilation of national recommended water quality criteria for the protection of aquatic life and human health...

  13. Sample quality criteria.

    Science.gov (United States)

    Ramsey, Charles A; Wagner, Claas

    2015-01-01

    The concept of Sample Quality Criteria (SQC) is the initial step in the scientific approach to representative sampling. It includes the establishment of sampling objectives, Decision Unit (DU), and confidence. Once fully defined, these criteria serve as input, in addition to material properties, to the Theory of Sampling for developing a representative sampling protocol. The first component of the SQC establishes these questions: What is the analyte(s) of concern? What is the concentration level of interest of the analyte(s)? How will inference(s) be made from the analytical data to the DU? The second component of the SQC establishes the DU, i.e., the scale at which decisions are to be made. On a large scale, a DU could be a ship or rail car; examples for small-scale DUs are individual beans, seeds, or kernels. A well-defined DU is critical because it defines the spatial and temporal boundaries of sample collection. SQC are not limited to a single DU; they can also include multiple DUs. The third SQC component, the confidence, establishes the desired probability that a correct inference (decision) can be made. The confidence level should typically correlate to the potential consequences of an incorrect decision (e.g., health or economic). The magnitude of combined errors in the sampling, sample processing and analytical protocols determines the likelihood of an incorrect decision. Thus, controlling error to a greater extent increases the probability of a correct decision. The required confidence level directly affects the sampling effort and QC measures.

  14. Criteria for Assessing Naturalistic Inquiries as Reports.

    Science.gov (United States)

    Lincoln, Yvonna S.; Guba, Egon G.

    Research on the assessment of naturalistic inquiries is reviewed, and criteria for assessment are outlined. Criteria reviewed include early foundational and non-foundational criteria, trustworthiness criteria, axiomatic criteria, rhetorical criteria, action criteria, and application/transferability criteria. Case studies that are reports of…

  15. The Quantitative Relationship Between ISO 15197 Accuracy Criteria and Mean Absolute Relative Difference (MARD) in the Evaluation of Analytical Performance of Self-Monitoring of Blood Glucose (SMBG) Systems.

    Science.gov (United States)

    Pardo, Scott; Simmons, David A

    2016-09-01

    The relationship between International Organization for Standardization (ISO) accuracy criteria and mean absolute relative difference (MARD), 2 methods for assessing the accuracy of blood glucose meters, is complex. While lower MARD values are generally better than higher MARD values, it is not possible to define a particular MARD value that ensures a blood glucose meter will satisfy the ISO accuracy criteria. The MARD value that ensures passing the ISO accuracy test can be described only as a probabilistic range. In this work, a Bayesian model is presented to represent the relationship between ISO accuracy criteria and MARD. Under the assumptions made in this work, there is nearly a 100% chance of satisfying ISO 15197:2013 accuracy requirements if the MARD value is between 3.25% and 5.25%. © 2016 Diabetes Technology Society.

  16. Decision criteria in PSA applications

    International Nuclear Information System (INIS)

    Holmberg, J.E.; Pulkkinen, U.; Rosqvist, T.; Simola, K.

    2001-11-01

    Along with the adoption of risk informed decision making principles, the need for formal probabilistic decision rule or criteria has been risen. However, there are many practical and theoretical problems in the application of probabilistic criteria. One has to think what is the proper way to apply probabilistic rules together with deterministic ones and how the criteria are weighted with respect to each other. In this report, we approach the above questions from the decision theoretic point of view. We give a short review of the most well known probabilistic criteria, and discuss examples of their use. We present a decision analytic framework for evaluating the criteria, and we analyse how the different criteria behave under incompleteness or uncertainty of the PSA model. As the conclusion of our analysis we give recommendations on the application of the criteria in different decision situations. (au)

  17. Admission Criteria for MBA Programs

    Directory of Open Access Journals (Sweden)

    Silvana Dakduk

    2016-11-01

    Full Text Available This paper reports a review of studies on admission criteria for MBA programs. The method consisted in a literary review based on a systematic search in international databases (Emerald, ABI/INFORM Global, ProQuest Education Journals, ProQuest European Business, ProQuest Science Journal, ProQuest Research Library, ProQuest Psychology Journals, ProQuest Social Science Journals and Business Source Complete of studies published from January 1990 to December 2013, which explore the academic performance of students or graduates of MBA programs. A quantitative review was performed. Results show that most researchers studied relations between GMAT (Graduate Management Admission Test and UGPA (Undergraduate Grade Point Average as predictors of GGPA (Graduate Grade Point Average. On the other hand, work experience and personal traits (such as personality, motivation, learning strategies, self-efficacy beliefs and achievement expectations and their relation with GGPA had been less studied, and results are not consistent enough to consider them valid predictors of student performance at this time.

  18. Comparison of Araoye's criteria with standard electrocardiographic ...

    African Journals Online (AJOL)

    Background: Left ventricular hypertrophy (LVH) is a major risk factor for cardiovascular morbidity and mortality. Various electrocardiographic (ECG) criteria for LHV give poorer performance in black subjects when compared with white subjects. Araoye proposed a code system for improved ECG diagnosis of LVH in blacks.

  19. 49 CFR 639.27 - Minimum criteria.

    Science.gov (United States)

    2010-10-01

    ... dollar value to any non-financial factors that are considered by using performance-based specifications..., DEPARTMENT OF TRANSPORTATION CAPITAL LEASES Cost-Effectiveness § 639.27 Minimum criteria. In making the... used where possible and appropriate: (a) Operation costs; (b) Reliability of service; (c) Maintenance...

  20. CDTI target selection criteria

    Science.gov (United States)

    Britt, C. L.; Davis, C. M.; Jackson, C. B.; Mcclellan, V. A.

    1984-01-01

    A Cockpit Display of Traffic Information (CDTI) is a cockpit instrument which provides information to the aircrew on the relative location of aircraft traffic in the vicinity of their aircraft (township). In addition, the CDTI may provide information to assist in navigation and in aircraft control. It is usually anticipated that the CDTI will be integrated with a horizontal situation indicator used for navigational purposes and/or with a weather radar display. In this study, several sets of aircraft traffic data are analyzed to determine statistics on the number of targets that will be displayed on a CDTI using various target selection criteria. Traffic data were obtained from an Atlanta Terminal Area Simulation and from radar tapes recorded at the Atlanta and Miami terminal areas. Results are given in the form of plots showing the average percentage of time (or probability) that an aircraft equipped with a CDTI would observe from 0 to 10 other aircraft on the display for range settings on the CDTI up to 30 n. mi. and using various target discrimination techniques.

  1. ACR appropriateness criteria jaundice.

    Science.gov (United States)

    Lalani, Tasneem; Couto, Corey A; Rosen, Max P; Baker, Mark E; Blake, Michael A; Cash, Brooks D; Fidler, Jeff L; Greene, Frederick L; Hindman, Nicole M; Katz, Douglas S; Kaur, Harmeet; Miller, Frank H; Qayyum, Aliya; Small, William C; Sudakoff, Gary S; Yaghmai, Vahid; Yarmish, Gail M; Yee, Judy

    2013-06-01

    A fundamental consideration in the workup of a jaundiced patient is the pretest probability of mechanical obstruction. Ultrasound is the first-line modality to exclude biliary tract obstruction. When mechanical obstruction is present, additional imaging with CT or MRI can clarify etiology, define level of obstruction, stage disease, and guide intervention. When mechanical obstruction is absent, additional imaging can evaluate liver parenchyma for fat and iron deposition and help direct biopsy in cases where underlying parenchymal disease or mass is found. Imaging techniques are reviewed for the following clinical scenarios: (1) the patient with painful jaundice, (2) the patient with painless jaundice, and (3) the patient with a nonmechanical cause for jaundice. The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed every 2 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances where evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment. Copyright © 2013 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  2. Criteria of site assessment

    International Nuclear Information System (INIS)

    Gibbs, P.; Fuchs, H.

    1975-01-01

    The criteria which lead to the choice of a particular site for a nuclear power station are in general very similar to those which would apply to any other type of power station. The principal differences derive from the simpler transport problems for the fuel compared with, say, solid fuel and the special safety considerations which attach to nuclear reactors. The search for a suitable site obviously starts by considering where the power is needed, i.e. where the load centers are and also the existing transmission network which may help to bring the power from a more remote site to the load centers. This economic incentive to put the plant close to loads conflicts directly with the nuclear safety argument which favours more remote siting, and part of the problem of site selection is to reconcile these two matters. In addition, there are many other important matters which will be considered later concerning the adequacy of cooling water supplies, foundation conditions, etc., all of which must be examined in considerable detail. (orig./TK) [de

  3. Criteria for safety-related operator actions

    International Nuclear Information System (INIS)

    Gray, L.H.; Haas, P.M.

    1983-01-01

    The Safety-Related Operator Actions (SROA) Program was designed to provide information and data for use by NRC in assessing the performance of nuclear power plant (NPP) control room operators in responding to abnormal/emergency events. The primary effort involved collection and assessment of data from simulator training exercises and from historical records of abnormal/emergency events that have occurred in operating plants (field data). These data can be used to develop criteria for acceptability of the use of manual operator action for safety-related functions. Development of criteria for safety-related operator actions are considered

  4. Multi-Criteria Recommender Systems

    Science.gov (United States)

    Adomavicius, Gediminas; Manouselis, Nikos; Kwon, Youngok

    This chapter aims to provide an overview of the class of multi-criteria recommender systems. First, it defines the recommendation problem as a multicriteria decision making (MCDM) problem, and reviews MCDM methods and techniques that can support the implementation of multi-criteria recommenders. Then, it focuses on the category of multi-criteria rating recommenders - techniques that provide recommendations by modelling a user's utility for an item as a vector of ratings along several criteria. A review of current algorithms that use multi-criteria ratings for calculating predictions and generating recommendations is provided. Finally, the chapter concludes with a discussion on open issues and future challenges for the class of multi-criteria rating recommenders.

  5. Heat exchanger staybolt acceptance criteria

    International Nuclear Information System (INIS)

    Lam, P.S.; Sindelar, R.L.; Barnes, D.M.

    1992-02-01

    The structural integrity demonstration of the primary coolant piping system includes evaluating the structural capacity of each component against a large break or equivalent Double-Ended Guillotine Break. A large break at the inlet or outlet heads of the heat exchangers would occur if the restraint members of the heads become inactive. The structural integrity of the heads is demonstrated by showing the redundant capacity of the staybolts to restrain the head at design conditions and under seismic loadings. The Savannah River Site heat exchanger head is attached to the tubesheet by 84 staybolts. Access to the staybolts is limited due to a welded seal cap over the staybolts. An ultrasonic testing (UT) inspection technique to provide an in-situ examination of the staybolts has recently been developed at SRS. Examination of the staybolts will be performed to ensure their service condition and configuration is within acceptance limits. An acceptance criteria methodology has been developed to disposition flaws reported in the staybolt inspections while ensuring adequate restraint capacity of the staybolts to maintain integrity of the heat exchanger heads against collapse. The methodology includes an approach for the baseline and periodic inspections of the staybolts. The heat exchanger head is analyzed with a three-dimensional finite element model. The restraint provided by the staybolts is evaluated for several postulated cases of inactive or missing staybolts. Evaluation of specific, inactive staybolt configurations based on the UT results can be performed with the finite element model and fracture methodology in this report

  6. Maintenance evaluation using risk based criteria

    International Nuclear Information System (INIS)

    Torres Valle, A.

    1996-01-01

    The maintenance evaluation is currently performed by using economic and, in some case, technical equipment failure criteria, however this is done to a specific equipment level. In general, when statistics are used the analysis for maintenance optimization are made isolated and whit a post mortem character; The integration provided by mean of Probabilistic Safety assessment (PSA) together with the possibilities of its applications, allow for evaluation of maintenance on the basis of broader scope criteria in regard to those traditionally used. The evaluate maintenance using risk based criteria, is necessary to follow a dynamic and systematic approach, in studying the maintenance strategy, to allow for updating the initial probabilistic models, for including operational changes that often take place during operation of complex facilities. This paper proposes a dynamic evaluation system of maintenance task. The system is illustrated by means of a practical example

  7. Plugging criteria for WWER SG tubes

    Energy Technology Data Exchange (ETDEWEB)

    Papp, L.; Wilam, M. [Vitkovice NPP Services (Switzerland); Herman, M. [Vuje, Trnava (Slovakia)

    1997-12-31

    At operated Czech and Slovak nuclear power plants the 80 % criteria for crack or other bulk defect depth is used for steam generator heat exchanging tubes plugging. This criteria was accepted as the recommendation of designer of WWER steam generators. Verification of this criteria was the objective of experimental program performed by Vitkovice, J.S.C., UJV Rez, J.S.C. and Vuje Trnava, J.S.C .. Within this program the following factors were studied: (1) Influence of secondary water chemistry on defects initiation and propagation, (2) Statistical evaluation of corrosion defects progression at operated SG, and (3) Determination of critical pressure for tube rupture as a function of eddy current indications. In this presentation items (2) and (3) are considered.

  8. Fibromyalgia diagnosis and diagnostic criteria.

    Science.gov (United States)

    Wolfe, Frederick; Häuser, Winfried

    2011-11-01

    Abstract Criteria for fibromyalgia developed from the conceptualization and hypotheses of Smythe and Moldofsky in 1977 and gradually evolved to a set of classification criteria endorsed by the American College of Rheumatology that emphasized tender points and widespread pain, measures of decreased pain threshold. In 2010, American College of Rheumatology fibromyalgia diagnostic criteria were published that abandoned the tender point count and placed increased emphasis of patient symptoms. The 2010 criteria also contained severity scales and offered physicians the opportunity to assess polysymptomatic distress on a continuous scale. This enabled physicians who were opposed to the idea of fibromyalgia to also assess and diagnose patients using an alternative nomenclature.

  9. Combining the IADPSG criteria with the WHO diagnostic criteria for ...

    African Journals Online (AJOL)

    Five pregnancy outcomes were observed, namely, pre‑eclampsia, shoulder dystocia or birth injury, birth weight ≥4.0 kg, clinical neonatal hypoglycaemia and birth asphyxia. Results: Twenty‑eight participants (21.5%) had GDM by the IADPSG criteria (GDMIADPSG) and 21 (16.2%) women had GDM by the WHO criteria ...

  10. New Two-Dimensional Polynomial Failure Criteria for Composite Materials

    OpenAIRE

    Zhao, Shi Yang; Xue, Pu

    2014-01-01

    The in-plane damage behavior and material properties of the composite material are very complex. At present, a large number of two-dimensional failure criteria, such as Chang-Chang criteria, have been proposed to predict the damage process of composite structures under loading. However, there is still no good criterion to realize it with both enough accuracy and computational performance. All these criteria cannot be adjusted by experimental data. Therefore, any special properties of composit...

  11. Principles and Criteria for Design

    DEFF Research Database (Denmark)

    Beghin, D.; Cervetto, D.; Hansen, Peter Friis

    1997-01-01

    The mandate of ISSC Committee IV.1 on principles and Criteria for Design is to report on the following:The ongoing concern for quantification of general economic and safety criteria for marine structures and for the development of appropriate principles for rational life cycle design using...

  12. AFRICAN PERSONALITY ASSESSMENT CRITERIA: YORUBA ...

    African Journals Online (AJOL)

    This analysis presents personality assessment criteria often used by the Yoruba as psychological tools to position an individual on the social responsibility scale and also to determine the norm compliant level of the Yoruba person. The study focused on four core criteria upon which such assessment is anchored, namely, ...

  13. Criteria for controlled atmosphere chambers

    International Nuclear Information System (INIS)

    Robinson, J.N.

    1980-03-01

    The criteria for design, construction, and operation of controlled atmosphere chambers intended for service at ORNL are presented. Classification of chambers, materials for construction, design criteria, design, controlled atmosphere chamber systems, and operating procedures are presented. ORNL Safety Manual Procedure 2.1; ORNL Health Physics Procedure Manual Appendix A-7; and Design of Viewing Windows are included in 3 appendices

  14. Mathematics Teachers' Criteria of Dimension

    Science.gov (United States)

    Ural, Alattin

    2014-01-01

    The aim of the study is to determine mathematics teachers' decisions about dimensions of the geometric figures, criteria of dimension and consistency of decision-criteria. The research is a qualitative research and the model applied in the study is descriptive method on the basis of general scanning model. 15 mathematics teachers attended the…

  15. Diagnostic criteria for vascular dementia

    NARCIS (Netherlands)

    Scheltens, P.; Hijdra, A. H.

    1998-01-01

    The term vascular dementia implies the presence of a clinical syndrome (dementia) caused by, or at least assumed to be caused by, a specific disorder (cerebrovascular disease). In this review, the various sets of criteria used to define vascular dementia are outlined. The various sets of criteria

  16. MHD-ETF design criteria

    Energy Technology Data Exchange (ETDEWEB)

    Retallick, F.D.

    1978-04-01

    This document establishes criteria to be utilized for the design of a pilot-scale (150 to 300 MW thermal) open cycle, coal-fired MHD/steam plant. Criteria for this Engineering Test Facility (ETF) are presented relative to plant siting, plant engineering and operations, MHD-ETF testing, costing and scheduling.

  17. New criteria to identify spectrum

    DEFF Research Database (Denmark)

    Jensen, Arne; Krishna, M.

    In this paper we give some new criteria for identifying the components of a probability measure, in its Lebesgue decomposition. This enables us to give new criteria to identify spectral types of self adjoint operators on Hilbert spaces, especially those of interest....

  18. New criteria to identify spectrum

    DEFF Research Database (Denmark)

    Jensen, Arne; Krishna, M.

    2005-01-01

    In this paper we give some new criteria for identifying the components of a probability measure, in its Lebesgue decomposition. This enables us to give new criteria to identify spectral types of self-adjoint operators on Hilbert spaces, especially those of interest....

  19. [Diagnostic criteria in acute neuromyelitis].

    Science.gov (United States)

    Panea, Cristina; Petrescu, Simona; Monica, Pop; Voinea, Liliana; Dascălu, Ana-Maria; Nicolae, Miruna; Ungureanu, E; Panca, Aida; Grădinaru, Sânziana

    2007-01-01

    Neuromyelitis optica, also known as Devic disease, was identified in the 19th century, is one of the inflammatory idiopathic demyelinating diseases of the central nervous system, often mistaken for severe multiple sclerosis. In 1999 it had been proposed diagnostic criteria for neuromyelitis optica, but in 2006 these criteria were revised by Dean Wingerchuck. These criteria are 99% sensitive and 90% specific for differentiating neuromyelitis optica from multiple sclerosis that present with optic neuritis or a myelitis syndrome. In the following article we present clinical, spinal and cerebral MR imaging, serological and aspects of cerebrospinal fluid examination features of neuromyelitis optica and the revised criteria of neuromyelitis optica established in 2006. The recently identified serum antibody biomarker: neuromyelitis optica immunoglobulin G (NMO Ig G), which target aquaporin 4 water channel, distinguish neuromyelitis optica from multiple sclerosis, is one of the revised criteria of neuromyelitis optica.

  20. User perspectives on relevance criteria

    DEFF Research Database (Denmark)

    Maglaughlin, Kelly L.; Sonnenwald, Diane H.

    2002-01-01

    , partially relevant, or not relevant to their information need; and explained their decisions in an interview. Analysis revealed 29 criteria, discussed positively and negatively, that were used by the participants when selecting passages that contributed or detracted from a document's relevance...... implications for relevance feedback in information retrieval systems, suggesting that systems accept and utilize multiple positive and negative relevance criteria from users. Systems designers may want to focus on supporting content criteria followed by full text criteria as these may provide the greatest cost....... These criteria can be grouped into six categories: abstract (e.g., citability, informativeness), author (e.g., novelty, discipline, affiliation, perceived status), content (e.g., accuracy/validity, background, novelty, contrast, depth/scope, domain, citations, links, relevant to other interests, rarity, subject...

  1. Failure Criteria for Reinforced Materials

    DEFF Research Database (Denmark)

    Rathkjen, Arne

    Failure of materials is often characterized as ductile yielding, brittle fracture, creep rupture, etc., and different criteria given in terms of different parameters have been used to describe different types of failure. Only criteria expressing failure in terms of stress are considered in what...... follows. The reinforcement here consists of long bars or fibres and complete bond between matrix and reinforcement is assumed so that no problems arising from incomplete transfer of adhesive and frictional forces are discussed. During loading, the reinforcement may yield, but total failure does not take...... certain restrictions on the form of the failure criteria for anisotropic materials. In section 2, some failure criteria for homogenous materials are reviewed. Both isotropic and anisotropic materials are described, and in particular the constraints imposed on the criteria from the symmetries orthotropy...

  2. Current quality criteria

    International Nuclear Information System (INIS)

    Sajaroff, Pedro M.

    1999-01-01

    The Safety Series 50-C/SG-Q 'Quality Assurance for Safety in Nuclear Power Plants and other Nuclear Installations' published by the IAEA in 1996, contains the Code and 14 Safety Guides. It is more addressed to operating organizations than to regulatory authorities. Priority is assigned to programme implementation and to work effectiveness. Emphasis is putted on doing work correctly from the very beginning (right first time attitude), and not on finding and correcting errors instead of preventing them. The essential aspects for assuring quality (that is, for achieving and maintaining an acceptable level of safety) cover the ten basic requirements established by the Code: Management (QA programme, training and qualification, non-conformance control and corrective actions, document control and records); Performance (work, design, procurement, inspection and testing for acceptance); and Assessment (management self-assessment, independent assessment). These requirements are applicable, on a graded approach basis, to the overall QA programme of the operating organization and its partial programmes during design, construction, commissioning, operation and decommissioning stages. The requirements can be also applied, with due adaptations, to other nuclear installations. The research and development activities related to such stages are comprised under the quality 'umbrella' as well. Therefore the scope of the traditional quality assurance is expanded and consolidated as a management tool more oriented to user. Responsibilities for achieving quality objectives are assigned to all involved individuals and organizations at all levels: management, working groups and assessment teams. Managers' is important but individual responsibilities are unavoidable. For the Argentine Nuclear Regulatory Authority, performance-based quality assurance was not a novelty. In line with the regulatory philosophy (which is essentially based on performance) the regulatory standard AR 3.6.1 (Rev.1

  3. Analytical Performance Requirements for Systems for Self-Monitoring of Blood Glucose With Focus on System Accuracy

    Science.gov (United States)

    Freckmann, Guido; Schmid, Christina; Baumstark, Annette; Rutschmann, Malte; Haug, Cornelia; Heinemann, Lutz

    2015-01-01

    In the European Union (EU), the ISO (International Organization for Standardization) 15197 standard is applicable for the evaluation of systems for self-monitoring of blood glucose (SMBG) before the market approval. In 2013, a revised version of this standard was published. Relevant revisions in the analytical performance requirements are the inclusion of the evaluation of influence quantities, for example, hematocrit, and some changes in the testing procedures for measurement precision and system accuracy evaluation, for example, number of test strip lots. Regarding system accuracy evaluation, the most important change is the inclusion of more stringent accuracy criteria. In 2014, the Food and Drug Administration (FDA) in the United States published their own guidance document for the premarket evaluation of SMBG systems with even more stringent system accuracy criteria than stipulated by ISO 15197:2013. The establishment of strict accuracy criteria applicable for the premarket evaluation is a possible approach to further improve the measurement quality of SMBG systems. However, the system accuracy testing procedure is quite complex, and some critical aspects, for example, systematic measurement difference between the reference measurement procedure and a higher-order procedure, may potentially limit the apparent accuracy of a given system. Therefore, the implementation of a harmonized reference measurement procedure for which traceability to standards of higher order is verified through an unbroken, documented chain of calibrations is desirable. In addition, the establishment of regular and standardized post-marketing evaluations of distributed test strip lots should be considered as an approach toward an improved measurement quality of available SMBG systems. PMID:25872965

  4. nuclear fuel design criteria

    International Nuclear Information System (INIS)

    Can, S.

    1997-01-01

    Nuclear fuel design is strictly dependent on reactor type and experiences obtained from performance of nuclear fuels. The objectives of the design are reliability, and economy. Nuclear fuel design requires an interdisciplinary work which has to cover, at least nuclear design, thermalhydraulic design, mechanical design, and material properties.The procedure of design, as describe in the quality assurance, consist of a number of steps. The most important parts are: Design description or inputs, preliminary design, detailed design and design output, and design verification. The first step covers objectives and requirements, as defined by the customer and by the regulatory authority for product performance,environmental factors, safety, etc. The second describes assumptions and alternatives, safety, economy and engineering analyses. The third covers technical specifications, design drawings, selection of QA program category, etc. The most important form of design verification is design review by qualified independent internal or external reviewers. The scope of the review depends on the specific character of the design work. Personnel involved in verification and review do not assume prime responsibility for detecting errors. Responsibility for the design remains with the personnel involved in the design work

  5. Optimal Control of Electrified Powertrains with the Use of Drive Quality Criteria

    Science.gov (United States)

    Bovee, Katherine

    In today's world, automotive manufacturers face the difficult challenge of building vehicles that are capable of meeting the increasingly stringent fuel economy and emissions standards, while also maintaining the performance and drive quality that consumers have come to expect. The automotive industry's response to this has been to make increasingly advanced vehicles that require more complex control systems, often resulting in longer development times and higher costs. One way to help reduce the development time and cost associated with these advanced vehicles is to use a model-based design approach. This approach allows engineers to design more of the vehicle's control system in a virtual environment, before hardware is available to test the control software. While model-based design techniques have helped reduce the amount of development time and cost that is needed to design the control system for a vehicle, these model-based techniques may not fully account for a vehicle's drive quality characteristics. Many of the energy management optimal control algorithms for hybrid vehicles designed in virtual environments today are capable of achieving high fuel economy numbers, but may result in poor drive quality characteristics when implemented on a vehicle. Therefore, a new methodology is needed to account for a vehicle's drive quality during the initial stages of a vehicle's control development. The research presented here describes a new methodology where drive quality metrics are added to the optimal control algorithm's cost function, in order to allow the algorithm to find a good balance between fuel economy and drive quality. Although some research has been previously published in this area, the majority of research does not specifically link the criteria used to improve drive quality to the physical behavior of the vehicle. Other research solves the optimal energy management problem to minimize fuel consumption, but then filters the results to prevent drive

  6. PERFORMANCE

    Directory of Open Access Journals (Sweden)

    M Cilli

    2014-10-01

    Full Text Available This study aimed to investigate the kinematic and kinetic changes when resistance is applied in horizontal and vertical directions, produced by using different percentages of body weight, caused by jumping movements during a dynamic warm-up. The group of subjects consisted of 35 voluntary male athletes (19 basketball and 16 volleyball players; age: 23.4 ± 1.4 years, training experience: 9.6 ± 2.7 years; height: 177.2 ± 5.7 cm, body weight: 69.9 ± 6.9 kg studying Physical Education, who had a jump training background and who were training for 2 hours, on 4 days in a week. A dynamic warm-up protocol containing seven specific resistance movements with specific resistance corresponding to different percentages of body weight (2%, 4%, 6%, 8%, 10% was applied randomly on non consecutive days. Effects of different warm-up protocols were assessed by pre-/post- exercise changes in jump height in the countermovement jump (CMJ and the squat jump (SJ measured using a force platform and changes in hip and knee joint angles at the end of the eccentric phase measured using a video camera. A significant increase in jump height was observed in the dynamic resistance warm-up conducted with different percentages of body weight (p 0.05. In jump movements before and after the warm-up, while no significant difference between the vertical ground reaction forces applied by athletes was observed (p>0.05, in some cases of resistance, a significant reduction was observed in hip and knee joint angles (p<0.05. The dynamic resistance warm-up method was found to cause changes in the kinematics of jumping movements, as well as an increase in jump height values. As a result, dynamic warm-up exercises could be applicable in cases of resistance corresponding to 6-10% of body weight applied in horizontal and vertical directions in order to increase the jump performance acutely.

  7. 45 CFR 1308.15 - Eligibility criteria: Autism.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Eligibility criteria: Autism. 1308.15 Section 1308... Services Performance Standards § 1308.15 Eligibility criteria: Autism. A child is classified as having autism when the child has a developmental disability that significantly affects verbal and non-verbal...

  8. Another Look at Some Information Order Selection Criteria in ...

    African Journals Online (AJOL)

    In this paper, the selection procedure of the order of an autoregressive process of order P, AR(p) using the information order selection criteria is considered. We compare the performance of three information criteria methods, the Akaike information criterion (AIC), Schwarz information criterion (BIC) and Hannan & Quinn ...

  9. Analysing and Comparing Encodability Criteria

    Directory of Open Access Journals (Sweden)

    Kirstin Peters

    2015-08-01

    Full Text Available Encodings or the proof of their absence are the main way to compare process calculi. To analyse the quality of encodings and to rule out trivial or meaningless encodings, they are augmented with quality criteria. There exists a bunch of different criteria and different variants of criteria in order to reason in different settings. This leads to incomparable results. Moreover it is not always clear whether the criteria used to obtain a result in a particular setting do indeed fit to this setting. We show how to formally reason about and compare encodability criteria by mapping them on requirements on a relation between source and target terms that is induced by the encoding function. In particular we analyse the common criteria full abstraction, operational correspondence, divergence reflection, success sensitiveness, and respect of barbs; e.g. we analyse the exact nature of the simulation relation (coupled simulation versus bisimulation that is induced by different variants of operational correspondence. This way we reduce the problem of analysing or comparing encodability criteria to the better understood problem of comparing relations on processes.

  10. Foreign criteria and programs

    International Nuclear Information System (INIS)

    Swinth, K.L.; Thompson, I.M.G.

    1993-03-01

    The concept of measurement quality assurance (MQA) as embodied in National Institute of Standards and Technology (NIST) programs is not generally used within European programs for testing or accreditation. Although the essential elements of quality control and quality assurance are in the European programs, the concept of testing the capability of the laboratory itself, in terms of its performance for the designated measurements, may not be included. Rather, the European programs use the concept of periodic calibration of laboratory reference standards against the next highest level of standards. Thus, they embody the concept of measurement traceability to appropriate primary standards. Within Europe a series of calibration accreditation programs has been established in the various countries tied together through a multilateral agreement. The radiation measurement programs are based on the International Organization for Standardization (ISO) 9000 series of standards. The purpose of this paper is to outline the overall operation of European Accreditation Programs in the radiation calibration and measurement areas. The operation of the radiation measurement programs of the National Measurement Accreditation Service (NAMAS) in the United Kingdom is described in detail along with other European programs. The manner in which these programs relate to individual dosimetry service programs is also described

  11. Criteria of Progress in Child Psychotherapies According to Psychotherapists

    Directory of Open Access Journals (Sweden)

    Lilian Pereira de Medeiros Guimarães

    2014-04-01

    Full Text Available This study aimed to perform a survey with psychotherapists, regarding the criteria they consider relevant to measure the progress of children in psychotherapy and whether the criteria indicated by them differ according to the therapist’s theoretical approach. Therapists were contacted electronically and answered a questionnaire composed of items with criteria of positive change present in the literature. Participants were 154 child therapists from different regions of Brazil. The analysis regarding the criteria of positive change that the participants indicated and their theoretical approach suggested that, despite the theoretical differences, in practice psychotherapists seem to adopt similar criteria to interpret progress in child psychotherapies. The criteria mentioned may be useful for a better systematization of the psychotherapy techniques for children. However, due to the lack of elements to evaluate the sample’s representativeness, caution is advised in generalizing the results.

  12. Nuclear Fuel Safety Criteria Technical Review - Second edition

    International Nuclear Information System (INIS)

    Beck, Winfried; Blanpain, Patrick; Fuketa, Toyoshi; Gorzel, Andreas; Hozer, Zoltan; Kamimura, Katsuichiro; Koo, Yang-Hyun; Maertens, Dietmar; Nechaeva, Olga; Petit, Marc; Rehacek, Radomir; Rey-Gayo, Jose Maria; Sairanen, Risto; Sonnenburg, Heinz-Guenther; Valach, Mojmir; Waeckel, Nicolas; Yueh, Ken; Zhang, Jinzhao; Voglewede, John

    2012-01-01

    Most of the current nuclear fuel safety criteria were established during the 1960's and early 1970's. Although these criteria were validated against experiments with fuel designs available at that time, a number of tests were based on unirradiated fuels. Additional verification was performed as these designs evolved, but mostly with the aim of showing that the new designs adequately complied with existing criteria, and not to establish new limits. In 1996, the OECD Nuclear Energy Agency (NEA) reviewed existing fuel safety criteria, focusing on new fuel and core designs, new cladding materials and industry manufacturing processes. The results were published in the Nuclear Fuel Safety Criteria Technical Review of 2001. The NEA has since re-examined the criteria. A brief description of each criterion and its rationale are presented in this second edition, which will be of interest to both regulators and industry (fuel vendors, utilities)

  13. Risk acceptance criteria of the Nuclear Regulatory Authority

    International Nuclear Information System (INIS)

    Felizia, Eduardo R.

    2005-01-01

    This report describes some of the regulatory and control functions legally conferred upon the Argentine Nuclear Regulatory Authority concerning radiological risks, as well as a critical analysis of the radiological risk acceptance criteria contained in the Argentine regulatory system. A summary of the application of regulatory standards AR 3.1.3. - 'Radiological criteria related to accidents in nuclear power reactors' and AR 4.1.3. - 'Radiological criteria related to accidents in research reactors' to concrete cases is made, while the favourable and unfavourable aspects of the risk acceptance criteria are discussed. The conclusion is that the Argentine regulatory system contains adequate radiological risk acceptance criteria, that the latter are consistent with the radiological protection principles applicable to man and that, for the moment, there is no need to perform any modifications that would broaden the conceptual framework on which such criteria are based. (author) [es

  14. Resource allocation criteria in a hospital

    OpenAIRE

    Bodina, A.; Pavan, A.; Castaldi, S.

    2017-01-01

    Summary Introduction. Allocate fixed resources among competing users is a challenge in terms of hospital management in order to obtain the best performance considering strategic objectives. In order to address this need, a system of evaluation in an important research and teaching hospital was designed. This study describes resource allocation criteria in a hospital focusing on the evaluation system and its developed application methodology. Methods. The indicator system allows the strategic ...

  15. Criteria for core sampling bit temperature monitor

    International Nuclear Information System (INIS)

    Francis, P.M.

    1994-08-01

    A temperature monitoring device needs to be developed for the tank core sampling trucks. It will provide an additional indication of safe drill bit temperatures and give the operator a better feel for the effects of changing drill settings. This document defines the criteria for the bit monitoring system, including performance requirements, information on the core sampling system, and other conditions that may be encountered

  16. New insights into the regulatory pathways associated with the activation of the stringent response in bacterial resistance to the PBP2-targeted antibiotics, mecillinam and OP0595/RG6080.

    Science.gov (United States)

    Doumith, M; Mushtaq, S; Livermore, D M; Woodford, N

    2016-10-01

    The diazabicyclooctane β-lactamase inhibitor OP0595 (RG6080) also acts as an antibiotic, targeting PBP2 in Enterobacteriaceae, but this activity is vulnerable to mutational resistance. We used WGS to investigate the basis of this resistance. Twenty OP0595-selected mutants, comprising four derived from each of five different Escherichia coli strains, were sequenced on Illumina HiSeq. Reads from each mutant were mapped to the assembled genome of the corresponding parent. A variant-calling file generated with Samtools was parsed to determine genetic alterations. Besides OP0595, the mutants consistently showed decreased susceptibility to mecillinam, which likewise targets PBP2, and grew as stable round forms in the presence of subinhibitory concentrations of OP0595. Among the 20 mutants, 18 had alterations in genes encoding tRNA synthase and modification functions liable to induce expression of the RpoS sigma factor through activation of the stringent response or had mutations suppressing inactivators of RpoS or the stringent response signal-degrading enzyme, SpoT. TolB was inactivated in one mutant: this activates RcsBC regulation and was previously associated with mecillinam resistance. The mechanism of resistance remained unidentified in one mutant. Both the RpoS and RcsBC systems regulate genes of cell division, including ftsAQZ that can compensate for loss or inhibition of PBP2, allowing survival of the challenged bacteria as stable round forms, as seen. WGS identified the global stringent response signal, entailing induction of RpoS, as the main mediator of mutational resistance to OP0595 in E. coli. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  17. Aquatic Life Criteria - Tributyltin (TBT)

    Science.gov (United States)

    Documents pertaining to 2004 Final Acute and Chronic Ambient Aquatic Life Water Quality Criteria for Tributyltin (TBT) for freshwater and saltwater. These documents include the safe levels of TBT that should protect the majority of species.

  18. Aquatic Life Criteria - Cadmium Documents

    Science.gov (United States)

    Documents pertaining to 2016 Acute and Chronic Aquatic Life Ambient Water Quality Criteria for Cadmium (Freshwater, Estuarine/marine). These documents contain the safe levels of Cadmium in water that should protect the majority of species.

  19. A Process For Performance Evaluation Of Real-Time Systems

    Directory of Open Access Journals (Sweden)

    Andrew J. Kornecki

    2003-12-01

    Full Text Available Real-time developers and engineers must not only meet the system functional requirements, but also the stringent timing requirements. One of the critical decisions leading to meeting these timing requirements is the selection of an operating system under which the software will be developed and run. Although there is ample documentation on real-time systems performance and evaluation, little can be found that combines such information into an efficient process for use by developers. As the software industry moves towards clearly defined processes, creation of appropriate guidelines describing a process for performance evaluation of real-time system would greatly benefit real-time developers. This technology transition research focuses on developing such a process. PROPERT (PROcess for Performance Evaluation of Real Time systems - the process described in this paper - is based upon established techniques for evaluating real-time systems. It organizes already existing real-time performance criteria and assessment techniques in a manner consistent with a well-formed process, based on the Personal Software Process concepts.

  20. Reliability criteria for voltage stability

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, Carson W.; Silverstein, Brian L. [Bonneville Power Administration, Portland, OR (United States)

    1994-12-31

    In face of costs pressures, there is need to allocate scare resources more effectively in order to achieve voltage stability. This naturally leads to development of probabilistic criteria and notions of rick management. In this paper it is presented a discussion about criteria for long term voltage stability limited to the case in which the time frames are topically several minutes. (author) 14 refs., 1 fig.

  1. Toxic chemical risk acceptance criteria

    International Nuclear Information System (INIS)

    Craig, D.K.; Davis, J.; Lee, L.; Lein, P.; Omberg, S.

    1992-01-01

    This paper presents recommendations of a subcommittee of the Westinghouse M ampersand 0 Nuclear Facility Safety Committee concerning toxic chemical risk acceptance criteria. Two sets of criteria have been developed, one for use in the hazard classification of facilities, and the second for use in comparing risks in DOE non-reactor nuclear facility Safety Analysis Reports. The Emergency Response Planning Guideline (ERPG) values are intended to provide estimates of concentration ranges for specific chemicals above which exposure would be expected to lead to adverse heath effects of increasing severity for ERPG-1, -2, and -3s. The subcommittee recommends that criteria for hazard class or risk range be based on ERPGs for all chemicals. Probability-based Incremental Cancer Risk (ICR) criteria are recommended for additional analyses of risks from all known or suspected human carcinogens. Criteria are given for both on-site and off-site exposure. The subcommittee also recommends that the 5-minute peak concentration be compared with the relevant criterion with no adjustment for exposure time. Since ERPGs are available for only a limited number of chemicals, the subcommittee has developed a proposed hierarchy of concentration limit parameters for the different criteria

  2. Stellarator optimization under several criteria using metaheuristics

    International Nuclear Information System (INIS)

    Castejón, F; Gómez-Iglesias, A; Vega-Rodríguez, M A; Jiménez, J A; Velasco, J L; Romero, J A

    2013-01-01

    A new algorithm based on metaheuristics has been developed to perform stellarator optimization. This algorithm, which is inspired by the behaviour of bees and is called distributed asynchronous bees, has been used for the optimization under three criteria: minimization of B × grad(B) drift, Mercier and ballooning stability. This algorithm is tested by partially optimizing TJ-II and, afterwards, a three-period optimized configuration is found by performing a full optimization that starts from a three-period heliac. (paper)

  3. Social Advertising Quality: Assessment Criteria

    Directory of Open Access Journals (Sweden)

    S. B. Kalmykov

    2017-01-01

    Full Text Available Purpose: the The purpose of the publication is development of existing criterial assessment in social advertising sphere. The next objectives are provided for its achievement: to establish research methodology, to develop the author’s version of necessary notional apparatus and conceptual generalization, to determine the elements of social advertising quality, to establish the factors of its quality, to conduct the systematization of existing criteria and measuring instruments of quality assessment, to form new criteria of social advertising quality, to apply received results for development of criterial assessment to determine the further research perspectives. Methods: the methodology of research of management of social advertising interaction with target audience, which has dynamic procedural character with use of sociological knowledge multivariate paradigmatic status, has been proposed. Results: the primary received results: the multivariate paradigmatic research basis with use of works of famous domestic and foreign scientists in sociology, qualimetry and management spheres; the definitions of social advertising, its quality, sociological quality provision system, target audience behavior model during social advertising interaction are offered; the quality factors with three groups by level of effect on consumer are established; the systematization of existing quality and its measure instruments assessment criteria by detected social advertising quality elements are conducted; the two new criteria and its management quality assessment measuring instruments in social advertising sphere are developed; the one of the common groups of production quality criteria – adaptability with considering of new management quality criteria and conducted systematization of existing social advertising creative quality assessment criteria development; the perspective of further perfection of quality criterial assessment based on social advertising

  4. Seismic re-evaluation criteria for Bohunice V1 reconstruction

    International Nuclear Information System (INIS)

    Campbell, R.; Schlund, H.; Warnken, L.

    2001-01-01

    Bohunice V1 in Slovakia is a Russian designed two unit WWER 440, Model 230 Pressurized Water Reactor. The plant was not originally designed for earthquake. Subsequent and ongoing reassessments now confirm that the seismic hazard at the site is significant. EBO, the plant owner has contracted with a consortium lead by Siemens AG (REKON) to do major reconstruction of the plant to significantly enhance its safety systems by the addition of new systems and the upgrading of existing systems. As part of the reconstruction, a complete seismic assessment and upgrading is required for existing safety relevant structures, systems and components. It is not practical to conduct this reassessment and upgrading using criteria applied to new design of nuclear power plants. Alternate criteria may be used to achieve adequate safety goals. Utilities in the U.S. have faced several seismic issues with operating NPPs and to resolve these issues, alternate criteria have been developed which are much more cost effective than use of criteria for new design. These alternate criteria incorporate the knowledge obtained from investigation of the performance of equipment in major earthquakes and include provisions for structures and passive equipment to deform beyond the yield point, yet still provide their essential function. IAEA has incorporated features of these alternate criteria into draft Technical Guidelines for application to Bohunice V1 and V2. REKON has developed plant specific criteria and procedures for the Bohunice V1 reconstruction that incorporate major features of the U.S. developed alternate criteria, comply to local codes and which envelop the draft IAEA Technical Guidelines. Included in these criteria and procedures are comprehensive walkdown screening criteria for equipment, piping, HVAC and cable raceways, analytical criteria which include inelastic energy absorption factors defined on an element basis and testing criteria which include specific guidance on interpretation

  5. Reactor tank UT acceptance criteria

    International Nuclear Information System (INIS)

    Daugherty, W.L.

    1990-01-01

    The SRS reactor tanks are constructed of type 304 stainless steel, with 0.5 inch thick walls. An ultrasonic (UT) in-service inspection program has been developed for examination of these tanks, in accordance with the ISI Plan for the Savannah River Production Reactors Process Water System (DPSTM-88-100-1). Prior to initiation of these inspections, criteria for the disposition of any indications that might be found are required. A working group has been formed to review available information on the SRS reactor tanks and develop acceptance criteria. This working group includes nationally recognized experts in the nuclear industry. The working group has met three times and produced three documents describing the proposed acceptance criteria, the technical basis for the criteria and a proposed initial sampling plan. This report transmits these three documents, which were prepared in accordance with the technical task plan and quality assurance plan for this task, task 88-001-A- 1. In addition, this report summarizes the acceptance criteria and proposed sampling plan, and provides further interpretation of the intent of these three documents where necessary

  6. Patient selection criteria for outpatient joint arthroplasty.

    Science.gov (United States)

    Kort, Nanne P; Bemelmans, Yoeri F L; van der Kuy, P Hugo M; Jansen, Jacqueline; Schotanus, Martijn G M

    2017-09-01

    General consensus of patient selection criteria for outpatient joint arthroplasty is lacking, which is paramount to prevent prolonged hospital stay, adverse events and/or readmissions. This review highlights patient selection criteria for OJA based on the current literature and expert opinion. A search of the English and International electronic healthcare databases including MEDLINE/PubMed, EMBASE, AMED and the Cochrane library was performed in November 2015 to include studies published during the last 10 years. Furthermore, a survey of physicians from different specialties was performed. Fourteen studies described results regarding outpatient joint arthroplasty. Studies on outpatient hip and/or knee arthroplasty resulted in similar outcome in preselected patients. Patients who are able and willing to participate, with a low ASA classification (II), bleeding disorders, poorly controlled and/or severe cardiac (e.g. heart failure, arrhythmia) or pulmonary (e.g. embolism, respiratory failure) comorbidities, uncontrolled DM (type I or II), a high BMI (>30 m 2 /kg), chronic opioid consumption, functional neurological impairments, dependent functional status, chronic/end-stage renal disease and/or reduced preoperative cognitive capacity should be excluded from outpatient joint arthroplasty. The expert opinion-based selection criteria were comparable to literature with a further extension of exclusion for patients with practical issue's, urologic medical history and/or severe mobility disorders. Based on the current literature, the presented patient selection criteria provide a basis for outpatient joint arthroplasty and can be useful when selecting patients. Together with a change in mindset, a multidisciplinary approach and literature-based protocols, outpatient joint arthroplasty can be applied in daily orthopaedic practice while ensuring patients' safety. Clinical review, Level III.

  7. Common criteria for usability review.

    Science.gov (United States)

    Nassar, Victor

    2012-01-01

    The propose of this paper is to present a literature review, in a grouping of common criteria for usability approaches of Bastien and Scapin (1993), Nielsen (1994), Shnneiderman(1998), Dix et al (1998), Preece et al (2005) and ISO 9241-110 (2006). After establishment of prerequisites for knowledge of the general characteristics of the users who will use the system, are defined and explained the criteria in common: consistency, user control, ease of learning, flexibility, errors management, reduction of excess and visibility system status. Although there is no determination as to which criteria should be considered when developing an interface and each author presents some specificity in their approach, it is observed that there is equivalence in the measures adopted usability.

  8. Combining the IADPSG criteria with the WHO diagnostic criteria for ...

    African Journals Online (AJOL)

    Background: Gestational diabetes mellitus (GDM) is associated with adverse pregnancy outcomes, yet there are no universally accepted diagnostic ... pregnancy outcome than a diagnosis that meets only WHO or IADPSG criteria. Key words: .... GDM, hypertensive disorder, maternal age, maternal obesity, family history of ...

  9. Combining the IADPSG criteria with the WHO diagnostic criteria for ...

    African Journals Online (AJOL)

    glucose, 1‑hour and 2‑hour serum glucose. Serum glucose was analysed on the Roche/Hitachi 902 automatic analyzer. The women were classified as gestational diabetics and non‑gestational diabetic according to the WHO and IADPSG diagnostic criteria. Five pregnancy outcome parameters were observed during the ...

  10. Design criteria for advanced reactors

    International Nuclear Information System (INIS)

    Dennielou, Y.

    1991-01-01

    Design criteria for advanced reactors are discussed, including safety aspects, site selection, problems related to maintenance and possibility of repairing or replacing structures or components of a nuclear power plant, the human factor considerations. Bearing in mind that some of these criteria are the subject of consensus at international level, the author suggests to establish a table of different operator requirements, to prepare a dossier on the comparison of input data for probabilistic risk analysis, to take into consideration the means to control a severe accident from the very start of the design

  11. Decision modeling and acceptance criteria

    DEFF Research Database (Denmark)

    Ditlevsen, Ove Dalager

    2003-01-01

    formulation of decision criteria and public acceptance criteria connected to risk analysis of technical operations that may endanger human life and property. Public restrictions on the decisions concerning the design, construction and managing of the technical operation have in the past been imposed......, the owner that tries to optimize the net gain of the operation, and the public that has somewhat different preferences than the owner, but also strong interests in the success of the owner. The principles of rational decision are needed for appreciation of the problem. Recognizing that there is an insurance...

  12. Criteria and procedures for stability studies - adopted measures for improving system dynamic performance; Criterios e procedimentos para estudos de estabilidade - definicao de acoes para a melhoria do desempenho em regime transitorio e dinamico de sistemas de transmissao

    Energy Technology Data Exchange (ETDEWEB)

    Figueiredo, Erli F. [FURNAS, Rio de Janeiro, RJ (Brazil); Fontoura, Roberto N. [ELETROBRAS, Rio de Janeiro, RJ (Brazil); Souza, Luiz Gastao C. [ELETROSUL, Curitiba, PR (Brazil); Barros, Joao Ricardo P. de [Companhia Hidroeletrica do Sao Francisco (CHESF), Recife, PE (Brazil); Aires, Joao C. de O. [Light Servicos de Eletricidade S.A., Rio de Janeiro, RJ (Brazil); Etrusco, Wellignton [Companhia Energetica de Sao Paulo (CESP), SP (Brazil); Rosa, Aciron B. de [Companhia Estadual de Energia Eletrica do Estado do Rio Grande do Sul (CEEE), Porto Alegre, RS (Brazil); Daldagan, Maria L. [Companhia Paranaense de Energia (COPEL), Curitiba, PR (Brazil); Bastos, Jose R. [Eletricidade de Sao Paulo, Sao Paulo, SP (Brazil); Yamamura, Paulo [ELETRONORTE, Belem, PA (Brazil); Luz, Ariosto [Companhia de Energia Eltrica da Bahia, Salvador, BA (Brazil); Oliveira, Elizabeth F. [CELG (Brazil); Mello, Albert C.G. de [Centro de Pesquisas de Energia Eletrica (CEPEL), Rio de Janeiro, RJ (Brazil); Souza, Itamar [Centrais Eletricas de Santa Catarina S.A. (CELESC), Florianopolis, SC (Brazil); Oliveira, Amaury R.C. [Companhia Energetica de Minas Gerais (CEMIG), Belo Horizonte, MG (Brazil); Martins Junior, Jose A. [Companhia Paulista de Forca e Luz (CPFL), Campinas, SP (Brazil); Ferreira, Jose S. [Espirito Santo Centrias Eletricas S.A. (ESCELSA), Vitotia, ES (Brazil); Molina, Jair M. [Empresa Energetica do Mato Grosso do Sul S.A. (ENERSUL), Campo Grande, MS (Brazil); Pereira, Marcel J.A. [Centrais Eltricas do Para S.A. (CELPA)]|[Belem, PA (Brazil); Rocha Neto, Cassiano, C. [Companhia Energetica do Ceara (COELCE), Fortaleza, CE (Brazil); Coelho, Simone N. [CELPE (Brazil); Silva, Robson P. [CEAL (Brazil)

    1994-12-31

    This work presents criterion and proceedings to the analysis of the performance of AC and DC transmission systems point to point and multi-terminal, in dynamic and transient regime. (author) 9 refs., 2 figs., 2 tabs.

  13. 7 CFR 1570.20 - Criteria.

    Science.gov (United States)

    2010-01-01

    ... Criteria § 1570.20 Criteria. The criteria considered by FAS in reviewing proposals for SOAP and COAP... initiatives will make toward realizing U.S. agricultural export goals and, in particular, in developing...

  14. Pressure broadening of the electric dipole and Raman lines of CO2 by argon: Stringent test of the classical impact theory at different temperatures on a benchmark system

    International Nuclear Information System (INIS)

    Ivanov, Sergey V.; Buzykin, Oleg G.

    2016-01-01

    A classical approach is applied to calculate pressure broadening coefficients of CO 2 vibration–rotational spectral lines perturbed by Ar. Three types of spectra are examined: electric dipole (infrared) absorption; isotropic and anisotropic Raman Q branches. Simple and explicit formulae of the classical impact theory are used along with exact 3D Hamilton equations for CO 2 –Ar molecular motion. The calculations utilize vibrationally independent most accurate ab initio potential energy surface (PES) of Hutson et al. expanded in Legendre polynomial series up to l max = 24. New improved algorithm of classical rotational frequency selection is applied. The dependences of CO 2 half-widths on rotational quantum number J up to J=100 are computed for the temperatures between 77 and 765 K and compared with available experimental data as well as with the results of fully quantum dynamical calculations performed on the same PES. To make the picture complete, the predictions of two independent variants of the semi-classical Robert-Bonamy formalism for dipole absorption lines are included. This method. however, has demonstrated poor accuracy almost for all temperatures. On the contrary, classical broadening coefficients are in excellent agreement both with measurements and with quantum results at all temperatures. The classical impact theory in its present variant is capable to produce quickly and accurately the pressure broadening coefficients of spectral lines of linear molecules for any J value (including high Js) using full-dimensional ab initio - based PES in the cases where other computational methods are either extremely time consuming (like the quantum close coupling method) or give erroneous results (like semi-classical methods). - Highlights: • Classical and semi-classical Ar-broadening coefficients for CO 2 . • Infrared absorption and Raman isotropic and anisotropic lines of CO 2 . Low and high temperatures. • Application of very accurate potential energy

  15. Assessment criteria weight in ranking land consolidation projects

    Directory of Open Access Journals (Sweden)

    Lazić Jelena

    2015-01-01

    Full Text Available The initiation and implementation of land consolidation projects are a complex and serious job, which carries a large financial investments, so fair and objective selection of cadastral municipality in which is going to be performed land redistribution of agricultural land is very important. Application of criteria optimization in recent times is an unavoidable segment in all spheres of science and profession, and therefore in the initiation of land consolidation projects is done too. The subject of this paper is multiple- criteria COPRAS method, with emphasis on different ways of subjective and objective assessments of the weight of defined criteria. The aim of the research was to determine the effect of different ways of assessing the weight of the criteria for the final ranking of alternatives in the application of multi-criteria COPRAS methods for ranking cadastral municipalities in the City of Ruma.

  16. Validation of proposed diagnostic criteria (the "Budapest Criteria") for Complex Regional Pain Syndrome

    NARCIS (Netherlands)

    Harden, R.N.; Bruehl, S.; Perez, R.S.G.M.; Birklein, F.; Marinus, J.; Maihofner, C.; Lubenow, T.; Buvanendran, A.; Mackey, S.; Graciosa, J.; Mogilevski, M.; Ramsden, C.; Chont, M.; Vatine, J.J.

    2010-01-01

    Current IASP diagnostic criteria for CRPS have low specificity, potentially leading to overdiagnosis. This validation study compared current IASP diagnostic criteria for CRPS to proposed new diagnostic criteria (the "Budapest Criteria") regarding diagnostic accuracy. Structured evaluations of

  17. Geomembrane selection criteria for uranium tailings ponds

    International Nuclear Information System (INIS)

    Mitchell, D.H.; Cuello, R.

    1986-09-01

    The selection criteria, particularly those involving chemical compatibility, of geomembranes to be used in ponds at uranium mill operations are discussed. The principal functional criteria which a geomembrane must meet for this application are: (1) a specified service life and (2) low permeability. Chemical compatibility with the waste is essential in meeting these functional criteria. In two different types of aging tests using simulated acidic uranium mill waste, degradation of chemical and physical properties were examined in geomembranes of high-density polyethylene, polyvinyl chloride, and chlorosulfonated polyethylene. Compatibility tests according to the National Sanitation Foundation procedures are recommended to ascertain the stability of certain physical properties of the proposed geomembrane. Actual experience with a specific geomembrane in an identical application is probably the best method to assure compatibility; however, this experience is frequently not available. Experience with a geomembrane in similar applications is valuable in the selection process, however, small differences in either the geomembrane formulation or the waste composition may result in large differences in performance of the geomembrane. It is likely that many geomembranes have acceptable chemical stability for typical uranium mill applications, therefore, additional factors in the selection processes will include seaming characteristics, mechanical properties, site characteristics, and costs

  18. Evaluating Dependence Criteria for Caffeine.

    Science.gov (United States)

    Striley, Catherine L W; Griffiths, Roland R; Cottler, Linda B

    2011-12-01

    Background: Although caffeine is the most widely used mood-altering drug in the world, few studies have operationalized and characterized Diagnostic and Statistical Manual IV (DSM-IV) substance dependence criteria applied to caffeine. Methods: As a part of a nosological study of substance use disorders funded by the National Institute on Drug Abuse, we assessed caffeine use and dependence symptoms among high school and college students, drug treatment patients, and pain clinic patients who reported caffeine use in the last 7 days and also reported use of alcohol, nicotine, or illicit drugs within the past year ( n =167). Results: Thirty-five percent met the criteria for dependence when all seven of the adopted DSM dependence criteria were used. Rates of endorsement of several of the most applicable diagnostic criteria were as follows: 26% withdrawal, 23% desire to cut down or control use, and 44% continued use despite harm. In addition, 34% endorsed craving, 26% said they needed caffeine to function, and 10% indicated that they talked to a physician or counselor about problems experienced with caffeine. There was a trend towards increased caffeine dependence among those dependent on nicotine or alcohol. Within a subgroup that had used caffeine, alcohol, and nicotine in the past year, 28% fulfilled criteria for caffeine dependence compared to 50% for alcohol and 80% for nicotine. Conclusion: The present study adds to a growing literature suggesting the reliability, validity, and clinical utility of the caffeine dependence diagnosis. Recognition of caffeine dependence in the DSM-V may be clinically useful.

  19. Evolving fuzzy rules for relaxed-criteria negotiation.

    Science.gov (United States)

    Sim, Kwang Mong

    2008-12-01

    In the literature on automated negotiation, very few negotiation agents are designed with the flexibility to slightly relax their negotiation criteria to reach a consensus more rapidly and with more certainty. Furthermore, these relaxed-criteria negotiation agents were not equipped with the ability to enhance their performance by learning and evolving their relaxed-criteria negotiation rules. The impetus of this work is designing market-driven negotiation agents (MDAs) that not only have the flexibility of relaxing bargaining criteria using fuzzy rules, but can also evolve their structures by learning new relaxed-criteria fuzzy rules to improve their negotiation outcomes as they participate in negotiations in more e-markets. To this end, an evolutionary algorithm for adapting and evolving relaxed-criteria fuzzy rules was developed. Implementing the idea in a testbed, two kinds of experiments for evaluating and comparing EvEMDAs (MDAs with relaxed-criteria rules that are evolved using the evolutionary algorithm) and EMDAs (MDAs with relaxed-criteria rules that are manually constructed) were carried out through stochastic simulations. Empirical results show that: 1) EvEMDAs generally outperformed EMDAs in different types of e-markets and 2) the negotiation outcomes of EvEMDAs generally improved as they negotiated in more e-markets.

  20. DOE natural phenomenal hazards design and evaluation criteria

    International Nuclear Information System (INIS)

    Murray, R.C.; Nelson, T.A.; Short, S.A.; Kennedy, R.P.; Chander, H.; Hill, J.R.; Kimball, J.K.

    1994-10-01

    It is the policy of the Department of Energy (DOE) to design, construct, and operate DOE facilities so that workers, the general public, and the environment are protected from the impacts of natural phenomena hazards (NPH). Furthermore, DOE has established explicit goals of acceptable risk for NPH performance. As a result, natural phenomena hazard (earthquake, extreme wind, and flood) design and evaluation criteria for DOE facilities have been developed based on target probabilistic performance goals. These criteria include selection of design/evaluation NPH input from probabilistic hazard curves combined with commonly practiced deterministic response evaluation methods and acceptance criteria with controlled levels of conservatism. For earthquake considerations, conservatism is intentionally introduced in specification of material strengths and capacities, in the allowance of limited inelastic behavior, and by a seismic scale factor. Criteria have been developed following a graded approach for several performance goals ranging from that appropriate for normal-use facilities to that appropriate for facilities involving hazardous or critical operations. Performance goals are comprised of qualitative expressions of acceptable behavior and of target quantitative probabilities that acceptable limits of behavior are maintained. The criteria are simple procedures but have a rigorous basis. This paper addresses DOE seismic design and evaluation criteria

  1. GENERATION OF MATCHING CRITERIA: A CASE OF CREATIVE BEHAVIOR

    Directory of Open Access Journals (Sweden)

    CLAUDIO CARPIO

    2006-01-01

    Full Text Available Conceiving creative behavior as generation of novel criteria that give rise to different contingencies(Carpio, 1999; 2005, the effects of two levels of variability in the conditions of training were comparedon the effective performance in transference tests and on the generation of matching criteria. 20 universitystudents randomly assigned to 4 experimental groups that distinguished themselves by the level of variabilityin the problems to solve participated. The results indicate that the variability significantly affects theexecution in transference tests and facilitates the generation of matching criteria. Finally, the possibilitiesthat experimental analysis has on the study of creative behavior are discussed.

  2. The Optimal Operation Criteria for a Gas Turbine Cogeneration System

    Directory of Open Access Journals (Sweden)

    Atsushi Akisawa

    2009-04-01

    Full Text Available The study demonstrated the optimal operation criteria of a gas turbine cogeneration system based on the analytical solution of a linear programming model. The optimal operation criteria gave the combination of equipment to supply electricity and steam with the minimum energy cost using the energy prices and the performance of equipment. By the comparison with a detailed optimization result of an existing cogeneration plant, it was shown that the optimal operation criteria successfully provided a direction for the system operation under the condition where the electric power output of the gas turbine was less than the capacity

  3. Environmental criteria in the Spanish Public Works Procurement Process

    OpenAIRE

    Fuentes Bargues, José Luis; González-Cruz, María-Carmen; González-Gaya, Cristina

    2017-01-01

    [EN] Green Public Procurement (GPP) is defined as a process of contracting products, services, and works with the least possible damage to the environment during their life cycle. In order to improve the knowledge about GPP, a study of the use of environmental tendering criteria in the Spanish public construction sector has been performed. The results of this study show that the use of environmental criteria in Spanish public sector construction procurement is low in comparison to a certain g...

  4. Environmental Criteria in the Spanish Public Works Procurement Process

    OpenAIRE

    José Luis Fuentes-Bargues; Mª Carmen González-Cruz; Cristina González-Gaya

    2017-01-01

    Green Public Procurement (GPP) is defined as a process of contracting products, services, and works with the least possible damage to the environment during their life cycle. In order to improve the knowledge about GPP, a study of the use of environmental tendering criteria in the Spanish public construction sector has been performed. The results of this study show that the use of environmental criteria in Spanish public sector construction procurement is low in comparison to a certain group ...

  5. Ferrocyanide Safety Program: Safety criteria for ferrocyanide watch list tanks

    International Nuclear Information System (INIS)

    Postma, A.K.; Meacham, J.E.; Barney, G.S.

    1994-01-01

    This report provides a technical basis for closing the ferrocyanide Unreviewed Safety Question (USQ) at the Hanford Site. Three work efforts were performed in developing this technical basis. The efforts described herein are: 1. The formulation of criteria for ranking the relative safety of waste in each ferrocyanide tank. 2. The current classification of tanks into safety categories by comparing available information on tank contents with the safety criteria; 3. The identification of additional information required to resolve the ferrocyanide safety issue

  6. 40 CFR 258.24 - Air criteria.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Air criteria. 258.24 Section 258.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.24 Air criteria. (a) Owners or operators of all MSWLFs must ensure that the units not violate any...

  7. 46 CFR 385.51 - Criteria: Projects.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Criteria: Projects. 385.51 Section 385.51 Shipping... COOPERATIVE AGREEMENTS REGULATIONS Criteria for Award § 385.51 Criteria: Projects. The criteria to be used by MarAd in evaluating all projects prior to award of a grant or cooperative agreement are as follows: (a...

  8. Reflexive criteria of sociological research

    Directory of Open Access Journals (Sweden)

    R T Ubaydullaeva

    2014-12-01

    Full Text Available The article is devoted to the sociological criteria of explaining the way of thinking and actions of subjects, their spiritual and moral positions and intellectual forces that form the laws of social life. The author seeks to adapt such categories as ‘meaning of life’, ‘human dignity’, ‘rationality’ etc. for the purposes of sociological analysis by methodological construction of some real life dichotomies such as ‘subjective meaning and social function’, ‘the real and the ideal’, ‘the demanded and the excluded’. Thus, the author studies economic, political and technical processes in terms of both positivity and negativity of social interaction and states that given the increasing differentiation of the society and the contradictory trends of social development the reflexive criteria that take into account the socio-cultural nature of the man help to find one’s own model of development.

  9. Prioritizing Zakat Core Principles Criteria

    Directory of Open Access Journals (Sweden)

    Aam Slamet Rusydiana

    2017-06-01

    Full Text Available Prioriting Zakat Core Principles CriteriaZakat Institution (OPZ is the intermediary organizations based on social. The entire of operating expense is taken from the zakat and infaq funds collected. The Zakat Core Principles are a starting point for the frameworks and standards of zakat-based governance best practices. The Zakat Core Principles is mainly aimed to improve the quality of the zakat systems by identifying such weaknesses in the existing of supervision and regulation. This study try to prioritize the Principles of ZCP and also the essential criteria from each level using Analytic Hierarchy Process (AHP.There are five core principles of charity principle, consisting of: regulation, supervision, collection and disbursement management, risk management, and audit and transparency. From these principles, the main priority is regulation following with audit and transparency.DOI: 10.15408/ess.v7i2.5275

  10. Four Criteria for Design Theories

    Directory of Open Access Journals (Sweden)

    Peter Hodges

    Full Text Available The goal of this paper is to demonstrate that the adoption of the four criteria we outline will strengthen future design theories and encourage existing design theories to expand or reconfigure in useful directions. We propose four criteria for design theory creation and evaluation. These are (1 the theory should have substantial design applications, and be applicable to any topic; (2 the theory should use propositions—if-then language—as a way of describing, explaining, and predicting actual and existing aspects of designing; (3 where appropriate, a new theory should accept and adopt propositions and language contained in other design theories; and (4 the theory should accommodate, or at least acknowledge, generative activity. We are not proposing a new general design theory—this paper outlines a strong approach to studying and building theory. Please also note that this essay does not pretend to exhaust a topic that has been discussed for at least the last 50 years.

  11. Uso da MCDA na identificação e mensuração da performance dos critérios para a certificação dos hospitais de ensino no âmbito do SUS The usage of MCDA in identification and measurement of criteria performance for certification of public teaching hospitals in Brazil

    Directory of Open Access Journals (Sweden)

    André Andrade Longaray

    2013-01-01

    Full Text Available O sistema de gestão da saúde pública brasileira passou por um processo de reestruturação nos últimos anos. Uma das consequências foi o estabelecimento de nova relação entre o Ministério da Saúde (MS e o Ministério da Educação (MEC no que tange ao financiamento dos hospitais universitários das universidades federais. Nesse sentido, o Ministério da Saúde implementou o processo de certificação dos hospitais universitários - um conjunto de metas a serem atingidas nos processos financeiro, de gestão e educação, bem como do modelo assistencial a ser seguido. Este artigo apresenta um método de análise de decisão multicritério aplicado no desenvolvimento de um modelo para auxiliar gestores de hospitais universitários a avaliarem o desempenho institucional no atendimento das metas pactuadas com o MS/MEC para a certificação. O estudo de caso foi realizado em um hospital da rede federal de educação do Brasil.The public health system management in Brazil has undergone a certain amount of restructuring over the past years. One consequence of the restructuring was the establishment of a new relationship between the Ministry of Health (MS and the Ministry of Education (MEC regarding the funding of University Hospitals of Federal Universities. Therefore, the Brazilian Ministry of Health has implemented the certification process of University Hospitals - a set of goals to be met concerning financial, management and education processes, as well as the assistance model to be adopted. This article presents the use of Multi Criteria Decision Analysis to support the development of a model aimed at assisting managers of a university hospital in assessing institutional performance, so that their goals jointly agreed between the MS/MEC can be met and certification is obtained. The case study was conducted within a hospital of the federal network of education in Brazil.

  12. Evaluating Dependence Criteria for Caffeine

    OpenAIRE

    Striley, Catherine L.W.; Griffiths, Roland R.; Cottler, Linda B.

    2011-01-01

    Background: Although caffeine is the most widely used mood-altering drug in the world, few studies have operationalized and characterized Diagnostic and Statistical Manual IV (DSM-IV) substance dependence criteria applied to caffeine. Methods: As a part of a nosological study of substance use disorders funded by the National Institute on Drug Abuse, we assessed caffeine use and dependence symptoms among high school and college students, drug treatment patients, and pain clinic patients who re...

  13. Repository operational criteria comparative analysis

    Energy Technology Data Exchange (ETDEWEB)

    Hageman, J.P.; Chowdhury, A.H. [Southwest Research Inst., San Antonio, TX (United States). Center for Nuclear Waste Regulatory Analyses

    1994-06-01

    The objective of the ``Repository Operational Criteria (ROC) Feasibility Studies`` (or ROC task) was to conduct comprehensive and integrated analyses of repository design, construction, and operations criteria in 10 CFR Part 60 regulations considering the interfaces among the components of the regulations and impacts of any potential changes to those regulations. The ROC task addresses regulatory criteria and uncertainties related to the preclosure aspects of the geologic repository. Those parts of 10 CFR Part 60 that require routine guidance or minor changes to the rule were addressed in Hageman and Chowdhury, 1992. The ROC task shows a possible need for further regulatory clarity, by major changes to the rule, related to the design bases and siting of a geologic repository operations area and radiological emergency planning in order to assure defense-in-depth. The analyses, presented in this report, resulted in the development and refinement of regulatory concepts and their supporting rationale for recommendations for potential major changes to 10 CFR Pan 0 regulations.

  14. A Study of Failure Criteria of Fibrous Composite Materials

    Science.gov (United States)

    Paris, Federico; Jackson, Karen E. (Technical Monitor)

    2001-01-01

    The research described in this paper is focused on two areas: (1) evaluation of existing composite failure criteria in the nonlinear, explicit transient dynamic finite element code, MSC.Dytran, and (2) exploration of the possibilities for modification of material and failure models to account for large deformations, progressive failure, and interaction of damage accumulation with stress/strain response of laminated composites. Following a review of the MSC.Dytran user manual, a bibliographical review of existing failure criteria of composites was performed. The papers considered most interesting for the objective of this report are discussed in section 2. The failure criteria included in the code under consideration are discussed in section 3. A critical summary of the present procedures to perform analysis and design of composites is presented in section 4. A study of the most important historical failure criteria for fibrous composite materials and some of the more recent modifications proposed were studied. The result of this analysis highlighted inadequacies in the existing failure criteria and the need to perform some numerical analyses to elucidate the answer to questions on which some of the proposed criteria are based. A summary of these ideas, which is a proposal of studies to be developed, is presented in section 5. Finally, some ideas for future developments are summarized in section 6.

  15. Analysis of improved criteria for mold growth in ASHRAE standard 160 by comparison with field observations

    Science.gov (United States)

    Samuel V. Glass; Stanley D. Gatland II; Kohta Ueno; Christopher J. Schumacher

    2017-01-01

    ASHRAE Standard 160, Criteria for Moisture-Control Design Analysis in Buildings, was published in 2009. The standard sets criteria for moisture design loads, hygrothermal analysis methods, and satisfactory moisture performance of the building envelope. One of the evaluation criteria specifies conditions necessary to avoid mold growth. The current standard requires that...

  16. Automated Transportation Management System (ATMS) V2.0 logistics module PBI acceptance criteria

    International Nuclear Information System (INIS)

    Weidert, R.S.

    1995-01-01

    This document defines the acceptance criteria for the Automated Transportation Management System V2.0 Logistics Module Performance Based Incentive (PBI). This acceptance criteria will be the primary basis for the generation of acceptance test procedures. The purpose of this document is to define the minimum criteria that must be fulfilled to guarantee acceptance of the Logistics Module

  17. How Turkey Meets MPOWER Criteria?

    Directory of Open Access Journals (Sweden)

    Nazmi Bilir

    2013-02-01

    Full Text Available In 2003 World Health Assembly adopted an international treaty on tobacco control; FCTC, Framework Convention on Tobacco Control. Five year later World Health Organization (WHO declared the six effective approach for tobacco control, under the name of MPOWER. In the following years, WHO evaluated the level of implementation of MPOWER criteria in the countries. In this article, how Turkey implemented these six criteria will be discussed. Monitor tobacco use and prevention policies: Monitoring of tobacco use prevalence has been successfully monitored in Turkey through Global Adult Tobacco Survey, Global Youth Tobacco Survey and Health Professionals Tobacco Use Survey. Nevertheless, monitoring of tobacco industry activities was not successfully implemented. Protect people from tobacco smoke: Smoking was banned in most of the indoor public places in Turkey since 1996, and Turkey became a complete smoke-free country by the exposion of smoke-free places including the hospitality workplaces in 2008. Offer help to quit tobacco use: Although smoking cessation services has been a bit late in Turkey, availability of smoking cessation drugs and the establishment of free quitline services made Turkey successful in this regard. Warn about the dangers of tobacco: Since 1996, all TV channels have a duty of broadcasting programs on harms of tobacco use, not less than 90 minutes in a month and it has been implemented successfully. Additionally written messages indicating harms of tobacco has been printed on the packs since 1988 and pictures was added in 2010. But since the average surface area covered by the messages in less than 50% of the total surface of the pack, Turkey was not regarded as to meet the requirement. Enforce bans on tobacco advertising, promotion and sponsorship: All kinds of tobacco advertisement and promotion was banned by the Law in 1996. But the tobacco products was not in closed boxes at the sales points. Turkey was not found as successful

  18. Analytical Performance Requirements for Systems for Self-Monitoring of Blood Glucose With Focus on System Accuracy: Relevant Differences Among ISO 15197:2003, ISO 15197:2013, and Current FDA Recommendations.

    Science.gov (United States)

    Freckmann, Guido; Schmid, Christina; Baumstark, Annette; Rutschmann, Malte; Haug, Cornelia; Heinemann, Lutz

    2015-07-01

    In the European Union (EU), the ISO (International Organization for Standardization) 15197 standard is applicable for the evaluation of systems for self-monitoring of blood glucose (SMBG) before the market approval. In 2013, a revised version of this standard was published. Relevant revisions in the analytical performance requirements are the inclusion of the evaluation of influence quantities, for example, hematocrit, and some changes in the testing procedures for measurement precision and system accuracy evaluation, for example, number of test strip lots. Regarding system accuracy evaluation, the most important change is the inclusion of more stringent accuracy criteria. In 2014, the Food and Drug Administration (FDA) in the United States published their own guidance document for the premarket evaluation of SMBG systems with even more stringent system accuracy criteria than stipulated by ISO 15197:2013. The establishment of strict accuracy criteria applicable for the premarket evaluation is a possible approach to further improve the measurement quality of SMBG systems. However, the system accuracy testing procedure is quite complex, and some critical aspects, for example, systematic measurement difference between the reference measurement procedure and a higher-order procedure, may potentially limit the apparent accuracy of a given system. Therefore, the implementation of a harmonized reference measurement procedure for which traceability to standards of higher order is verified through an unbroken, documented chain of calibrations is desirable. In addition, the establishment of regular and standardized post-marketing evaluations of distributed test strip lots should be considered as an approach toward an improved measurement quality of available SMBG systems. © 2015 Diabetes Technology Society.

  19. Fuzzy Multiple Criteria Decision Making Model with Fuzzy Time Weight Scheme

    OpenAIRE

    Chin-Yao Low; Sung-Nung Lin

    2013-01-01

    In this study, we purpose a common fuzzy multiple criteria decision making model. A brand new concept - fuzzy time weighted scheme is adopted for considering in the model to establish a fuzzy multiple criteria decision making with time weight (FMCDMTW) model. A real case of fuzzy multiple criteria decision making (FMCDM) problems to be considering in this study. The performance evaluation of auction websites based on all criteria proposed in related literature. Obviously, the problem under in...

  20. STOPP/START criteria for potentially inappropriate prescribing in older people: version 2.

    Science.gov (United States)

    O'Mahony, Denis; O'Sullivan, David; Byrne, Stephen; O'Connor, Marie Noelle; Ryan, Cristin; Gallagher, Paul

    2015-03-01

    Screening tool of older people's prescriptions (STOPP) and screening tool to alert to right treatment (START) criteria were first published in 2008. Due to an expanding therapeutics evidence base, updating of the criteria was required. We reviewed the 2008 STOPP/START criteria to add new evidence-based criteria and remove any obsolete criteria. A thorough literature review was performed to reassess the evidence base of the 2008 criteria and the proposed new criteria. Nineteen experts from 13 European countries reviewed a new draft of STOPP & START criteria including proposed new criteria. These experts were also asked to propose additional criteria they considered important to include in the revised STOPP & START criteria and to highlight any criteria from the 2008 list they considered less important or lacking an evidence base. The revised list of criteria was then validated using the Delphi consensus methodology. The expert panel agreed a final list of 114 criteria after two Delphi validation rounds, i.e. 80 STOPP criteria and 34 START criteria. This represents an overall 31% increase in STOPP/START criteria compared with version 1. Several new STOPP categories were created in version 2, namely antiplatelet/anticoagulant drugs, drugs affecting, or affected by, renal function and drugs that increase anticholinergic burden; new START categories include urogenital system drugs, analgesics and vaccines. STOPP/START version 2 criteria have been expanded and updated for the purpose of minimizing inappropriate prescribing in older people. These criteria are based on an up-to-date literature review and consensus validation among a European panel of experts. © The Author 2014. Published by Oxford University Press on behalf of the British Geriatrics Society.

  1. The DSM diagnostic criteria for gender identity disorder in adolescents and adults.

    Science.gov (United States)

    Cohen-Kettenis, Peggy T; Pfäfflin, Friedemann

    2010-04-01

    Apart from some general issues related to the Gender Identity Disorder (GID) diagnosis, such as whether it should stay in the DSM-V or not, a number of problems specifically relate to the current criteria of the GID diagnosis for adolescents and adults. These problems concern the confusion caused by similarities and differences of the terms transsexualism and GID, the inability of the current criteria to capture the whole spectrum of gender variance phenomena, the potential risk of unnecessary physically invasive examinations to rule out intersex conditions (disorders of sex development), the necessity of the D criterion (distress and impairment), and the fact that the diagnosis still applies to those who already had hormonal and surgical treatment. If the diagnosis should not be deleted from the DSM, most of the criticism could be addressed in the DSM-V if the diagnosis would be renamed, the criteria would be adjusted in wording, and made more stringent. However, this would imply that the diagnosis would still be dichotomous and similar to earlier DSM versions. Another option is to follow a more dimensional approach, allowing for different degrees of gender dysphoria depending on the number of indicators. Considering the strong resistance against sexuality related specifiers, and the relative difficulty assessing sexual orientation in individuals pursuing hormonal and surgical interventions to change physical sex characteristics, it should be investigated whether other potentially relevant specifiers (e.g., onset age) are more appropriate.

  2. New Splitting Criteria for Decision Trees in Stationary Data Streams.

    Science.gov (United States)

    Jaworski, Maciej; Duda, Piotr; Rutkowski, Leszek

    2017-05-10

    The most popular tools for stream data mining are based on decision trees. In previous 15 years, all designed methods, headed by the very fast decision tree algorithm, relayed on Hoeffding's inequality and hundreds of researchers followed this scheme. Recently, we have demonstrated that although the Hoeffding decision trees are an effective tool for dealing with stream data, they are a purely heuristic procedure; for example, classical decision trees such as ID3 or CART cannot be adopted to data stream mining using Hoeffding's inequality. Therefore, there is an urgent need to develop new algorithms, which are both mathematically justified and characterized by good performance. In this paper, we address this problem by developing a family of new splitting criteria for classification in stationary data streams and investigating their probabilistic properties. The new criteria, derived using appropriate statistical tools, are based on the misclassification error and the Gini index impurity measures. The general division of splitting criteria into two types is proposed. Attributes chosen based on type-$I$ splitting criteria guarantee, with high probability, the highest expected value of split measure. Type-$II$ criteria ensure that the chosen attribute is the same, with high probability, as it would be chosen based on the whole infinite data stream. Moreover, in this paper, two hybrid splitting criteria are proposed, which are the combinations of single criteria based on the misclassification error and Gini index.

  3. Quantitative Analysis of Criteria in University Building Maintenance in Malaysia

    Directory of Open Access Journals (Sweden)

    Olanrewaju Ashola Abdul-Lateef

    2010-10-01

    Full Text Available University buildings are a significant part of university assets and considerable resources are committed to their design, construction and maintenance. The core of maintenance management is to optimize productivity and user satisfaction with optimum resources. An important segment in the maintenance management system is the analysis of criteria that influence building maintenance. Therefore, this paper aims to identify quantify, rank and discuss the criteria that influence maintenance costs, maintenance backlogs, productivity and user satisfaction in Malaysian university buildings. The paper reviews the related literature and presents the outcomes of a questionnaire survey. Questionnaires were administered on 50 university maintenance organizations. Thirty-one criteria were addressed to the university maintenance organizations to evaluate the degree to which each of the criteria influences building maintenance management. With a 66% response rate, it was concluded that the consideration of the criteria is critical to the university building maintenance management system. The quality of components and materials, budget constraints and the age of the building were found to be the most influential criteria but information on user performance satisfaction, problems associated with in-house workforce and shortage of materials and components were the least influential criteria. The paper also outlined that maintenance management is a strategic function in university administration.

  4. Assessment of Clinical Criteria for Sepsis

    Science.gov (United States)

    Seymour, Christopher W.; Liu, Vincent X.; Iwashyna, Theodore J.; Brunkhorst, Frank M.; Rea, Thomas D.; Scherag, André; Rubenfeld, Gordon; Kahn, Jeremy M.; Shankar-Hari, Manu; Singer, Mervyn; Deutschman, Clifford S.; Escobar, Gabriel J.; Angus, Derek C.

    2016-01-01

    IMPORTANCE The Third International Consensus Definitions Task Force defined sepsis as “life-threatening organ dysfunction due to a dysregulated host response to infection.” The performance of clinical criteria for this sepsis definition is unknown. OBJECTIVE To evaluate the validity of clinical criteria to identify patients with suspected infection who are at risk of sepsis. DESIGN, SETTINGS, AND POPULATION Among 1.3 million electronic health record encounters from January 1, 2010, to December 31, 2012, at 12 hospitals in southwestern Pennsylvania, we identified those with suspected infection in whom to compare criteria. Confirmatory analyses were performed in 4 data sets of 706 399 out-of-hospital and hospital encounters at 165 US and non-US hospitals ranging from January 1, 2008, until December 31, 2013. EXPOSURES Sequential [Sepsis-related] Organ Failure Assessment (SOFA) score, systemic inflammatory response syndrome (SIRS) criteria, Logistic Organ Dysfunction System (LODS) score, and a new model derived using multivariable logistic regression in a split sample, the quick Sequential [Sepsis-related] Organ Failure Assessment (qSOFA) score (range, 0–3 points, with 1 point each for systolic hypotension [≤100 mm Hg], tachypnea [≥22/min], or altered mentation). MAIN OUTCOMES AND MEASURES For construct validity, pairwise agreement was assessed. For predictive validity, the discrimination for outcomes (primary: in-hospital mortality; secondary: in-hospital mortality or intensive care unit [ICU] length of stay ≥3 days) more common in sepsis than uncomplicated infection was determined. Results were expressed as the fold change in outcome over deciles of baseline risk of death and area under the receiver operating characteristic curve (AUROC). RESULTS In the primary cohort, 148 907 encounters had suspected infection (n = 74 453 derivation; n = 74 454 validation), of whom 6347 (4%) died. Among ICU encounters in the validation cohort (n = 7932 with suspected

  5. Summary of the evidence file demonstrating completion of the NIF Project Completion Criteria

    Energy Technology Data Exchange (ETDEWEB)

    Haynam, C. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2014-12-04

    This document summarizes the results of performance verification tests on NIF that demonstrate it has met its performance-related Project Completion Criteria (PCC). It includes measurements made on NIF with the NIF diagnostics, the calibration of these diagnostics and the supporting analyses that verify the NIF performance criteria have been met.

  6. Validating a Methodology for Establishing a Criteria and Proficiency Levels in Surgical Skills Simulators

    National Research Council Canada - National Science Library

    Heinrichs, LeRoy; Lukoff, Brian; Youngblood, Patricia; Dev, Parvati; Shavelson, Richard

    2006-01-01

    .... To establish training criteria, we have assessed the performance of 18 experienced laparoscopic surgeons basic technical surgical skills of recorded electronically in 26 basic skills modules selected...

  7. Patients with fibromyalgia rarely fulfil classification criteria for axial spondyloarthritis.

    Science.gov (United States)

    Baraliakos, Xenofon; Regel, Andrea; Kiltz, Uta; Menne, Hans-Jürgen; Dybowski, Friedrich; Igelmann, Manfred; Kalthoff, Ludwig; Krause, Dietmar; Saracbasi-Zender, Ertan; Schmitz-Bortz, Elmar; Braun, Jürgen

    2017-09-06

    The Assessments of Spondyloarthritis international Society (ASAS) classification criteria for axial spondyloarthritis (axSpA) have been criticized because of insufficient differentiation towards FM. The aim of this study was to compare the performance of currently used classification criteria in patients diagnosed with axSpA or FM. Patients were prospectively included if diagnosed with axSpA or FM by the treating rheumatologist and evaluated by an independent examiner for fulfilment of the classification criteria for axSpA (ASAS criteria) and/or FM (1990 ACR classification and 2010 ACR diagnostic criteria). Patients with axSpA were stratified based on classification as non-radiographic axSpA (nr-axSpA) or AS. Symptom severity was assessed by established disease-related questionnaires. Overall, 300 patients were included, 100 with FM and 200 with axSpA of which 100 each had nr-axSpA and AS. Almost all FM patients fulfilled the 2010 (100%) and 1990 ACR criteria (98%) for FM, but only 2% fulfilled the ASAS criteria. When calculations were based on only the FM patients with available HLA-B27 results (n = 40), the proportion fulfilling the ASAS criteria was 5%. All axSpA patients met the ASAS criteria but also the 2010 (24%) and 1990 (13.5%) FM criteria. More patients with AS (29% and 19%) than with nr-axSpA (19% and 8%) fulfilled the 2010 and 1990 FM criteria, respectively. FM patients only rarely fulfil classification criteria for axSpA but some axSpA patients also fulfil FM criteria. Since this was more frequent in patients with AS it may be related to the severity and duration of chronic pain in axSpA patients. Assessment instruments evaluated in axSpA are not disease-specific. The phenomenon of central pain sensitization in rheumatic diseases deserves more study. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  8. Quality criteria for landscape visualisation

    International Nuclear Information System (INIS)

    Waldi, H.-P.; Witt, U. de

    1996-01-01

    The rapid expansion of wind energy utilisation in Western Europe can strain the limits of social acceptance with citizens living in wind development areas. One of the problems wind farm engineers and local authorities face is the visual impact of wind turbines. To determine the influence on the landscape visualisations of wind farms photorealistic compositions are used. In many cases it is part of the planning procedure. The quality of this visualization can strongly influence the success of the permission procedure. We will give criteria which can give help to reduce the possibility of unwanted manipulations. (author)

  9. Training review criteria and procedures

    International Nuclear Information System (INIS)

    1993-01-01

    This document provides direction to NRC personnel for reviewing training programs at nuclear power plants to verify compliance with the requirements of 10 CFR 50. 120 and 10 CFR 55 as applicable. It describes the process for evaluating the effectiveness of training programs, provides aids for collection of information during interviews and observations, and provides criteria for evaluating the implementation of a systems approach to training. This document is not intended to have the effect of a regulation, it establishes no binding requirements or interpretations of NRC regulations. It is intended as guidance only

  10. [Diagnostics, classification and prognostic criteria of acute myeloid leukemia].

    Science.gov (United States)

    Heilmeier, Bernhard; Buske, Christian; Spiekermann, Karsten; Bohlander, Stefan; Feuring-Buske, Michaela; Hiddemann, Wolfgang; Braess, Jan

    2007-04-15

    The continuously growing knowledge about criteria important for biology, pathogenesis, prognosis and treatment of acute myeloid leukemia (AML) necessitates a broad spectrum of diagnostic methods for first diagnosis and for the further course of the disease. Relevant diagnostic techniques (cytomorphology with cytochemistry, immunophenotyping, cytogenetics and molecular genetics, DNA array) are described - with a focus on their mode of operation as well on their clinical significance. Due to the high clinical relevance and growing complexity, AML diagnostics should be performed in specialized laboratories. Compared to the FAB classification which is based primarily on morphological criteria, the classification recommended in 2001 by the WHO additionally takes cytogenetics, molecular genetics and further clinical factors into consideration. Both classifications are described. A wide range of prognostic criteria of AML is discussed on the basis of currently available clinical data. The most important criteria are the karyotype of the leukemic clone and the patient's age.

  11. Acceptability criteria for final underground disposal of radioactive waste

    International Nuclear Information System (INIS)

    Sousselier, Y.

    1984-01-01

    Specialists now generally agree that the underground disposal of suitably immobilized radioactive waste offers a means of attaining the basic objective of ensuring the immediate and long-term protection of man and the environment throughout the requisite period of time and in all foreseeable circumstances. Criteria of a more general as well as a more specific nature are practical means through which this basic protection objective can be reached. These criteria, which need not necessarily be quantified, enable the authorities to gauge the acceptability of a given project and provide those responsible for waste management with a basis for making decisions. In short, these principles constitute the framework of a suitably safety-oriented waste management policy. The more general criteria correspond to the protection objectives established by the national authorities on the basis of principles and recommendations formulated by international organizations, in particular the ICRP and the IAEA. They apply to any underground disposal system considered as a whole. The more specific criteria provide a means of evaluating the degree to which the various components of the disposal system meet the general criteria. They must also take account of the interaction between these components. As the ultimate aim is the overall safety of the disposal system, individual components can be adjusted to compensate for the performance of others with respect to the criteria. This is the approach adopted by the international bodies and national authorities in developing acceptability criteria for the final underground radioactive disposal systems to be used during the operational and post-operational phases respectively. The main criteria are reviewed and an attempt is made to assess the importance of the specific criteria according to the different types of disposal systems. (author)

  12. Nuclear reactor philosophy and criteria

    International Nuclear Information System (INIS)

    Atchison, R.J.

    1979-07-01

    Nuclear power plant safety criteria and principles developed in Canada are directed towards minimizing the chance of failure of the fuel and preventing or reducing to an acceptably low level the escape of fission products should fuel failure occur. Safety criteria and practices are set forth in the Reactor Siting Guide, which is based upon the concept of defence in depth. The Guide specifies that design and construction shall follow the best applicable code, standard or practice; the total of all serious process system failures shall not exceed one in three years; special safety systems are to be physically and functionally separate from process systems and each other; and safety systems shall be testable, with unavailability less than 10 - 3 . Doses to the most exposed member of the public due to normal operation, serious process failures, and dual failures are specified. Licensees are also required to consider the effects of extreme conditions due to airplane crashes, explosions, turbine disintegration, pipe burst, and natural disasters. Safety requirements are changing as nuclear power plant designs evolve and in response to social and economic pressures

  13. Donor selection criteria and procurement

    International Nuclear Information System (INIS)

    Agcaoili, N.R.

    1999-01-01

    Donor selection is one of the most important aspects of tissue banking practice. Without a good donor selection criteria, the results of any effort of trying to preserve tissues will have disastrous outcome for the recipient of these tissues. While with a very good and strict donor selection the Tissue Bank can guarantee safe and effective tissue allografts. There are significant aspects in the history and physical examination of the donor that must be emphasized. A donor exclusion criteria has also been formulated together with a list of all the needed laboratory examinations to eliminate possible diseases that may be transferred from the donor. The methods of procurement of tissue allografts from living and cadaver donors will be described. The limitations and advantages of each will be taken.There are also special restrictions that are important in the practice of removing the tissues from the donors. All the necessary equipment should be ready and the potential risk on the personnel should be known to all doing Tissue Banking

  14. Proposed Diagnostic Criteria for Smartphone Addiction.

    Science.gov (United States)

    Lin, Yu-Hsuan; Chiang, Chih-Lin; Lin, Po-Hsien; Chang, Li-Ren; Ko, Chih-Hung; Lee, Yang-Han; Lin, Sheng-Hsuan

    2016-01-01

    Global smartphone penetration has led to unprecedented addictive behaviors. The aims of this study are to develop diagnostic criteria of smartphone addiction and to examine the discriminative ability and the validity of the diagnostic criteria. We developed twelve candidate criteria for characteristic symptoms of smartphone addiction and four criteria for functional impairment caused by excessive smartphone use. The participants consisted of 281 college students. Each participant was systematically assessed for smartphone-using behaviors by psychiatrist's structured diagnostic interview. The sensitivity, specificity, and diagnostic accuracy of the candidate symptom criteria were analyzed with reference to the psychiatrists' clinical global impression. The optimal model selection with its cutoff point of the diagnostic criteria differentiating the smartphone addicted subjects from non-addicted subjects was then determined by the best diagnostic accuracy. Six symptom criteria model with optimal cutoff point were determined based on the maximal diagnostic accuracy. The proposed smartphone addiction diagnostic criteria consisted of (1) six symptom criteria, (2) four functional impairment criteria and (3) exclusion criteria. Setting three symptom criteria as the cutoff point resulted in the highest diagnostic accuracy (84.3%), while the sensitivity and specificity were 79.4% and 87.5%, respectively. We suggested determining the functional impairment by two or more of the four domains considering the high accessibility and penetration of smartphone use. The diagnostic criteria of smartphone addiction demonstrated the core symptoms "impaired control" paralleled with substance related and addictive disorders. The functional impairment involved multiple domains provide a strict standard for clinical assessment.

  15. Resource allocation criteria in a hospital.

    Science.gov (United States)

    Bodina, A; Pavan, A; Castaldi, S

    2017-06-01

    Allocate fixed resources among competing users is a challenge in terms of hospital management in order to obtain the best performance considering strategic objectives. In order to address this need, a system of evaluation in an important research and teaching hospital was designed. This study describes resource allocation criteria in a hospital focusing on the evaluation system and its developed application methodology. The indicator system allows the strategic management to rapidly detect the priorities in the evaluations of the Strategic, Organizational, Managerial, Economic, Research and Qualitative conditions of each unit. The chosen indicators are expressed with three numerical values, (1 indicating critical status, 2 acceptable conditions and 3 a good operational situation). The adopted evaluation system considered different thematic areas: Strategic, Organizational, Managerial, Economic, Research and Qualitative. In order to define each area, 3 fields of evaluation have been chosen. The indicators have been structured according to a pyramid system allowing creating a single indicator for each area for each unit. Furthermore, a single indicator has been fixed in order to facilitate a first consideration on whether to carry out or not closer examinations of the most critical units. This manuscript describes an attempt to define objective criteria for the allocation of scarce resources in order to achieve the hospital's strategic objectives. The indicators identified allow to obtain an overall score for each unit, which allows the management to prioritize the needs.

  16. [Occupational disability in epilepsy. The assessment criteria].

    Science.gov (United States)

    Vicente-Herrero, M T; Terradillos García, M J; Capdevila García, L; Ramírez Iñiguez de la Torre, M V; López-González, Á A; Aguilar Jiménez, E

    2016-03-01

    Epilepsy is a chronic disease cursing with recurrent and paroxysmal crises due to anomalies in the electrical activity of brain, and is controllable in most of the patients by using antiepileptic drugs, in single or combination therapy. Probably one of the most complex aspects of epilepsy is the assessment of disability for work of the affected person. For this purpose, multiple factors need to be taken into account for homogeneous decision-making, and according to criteria of approval and within the principle of equity inherent in the granting of Social Security disability benefits. This requires the cooperation of all professionals involved in the different specialties, with reports using common criteria and taking into account the disease itself, as well as the effects of the prescribed treatments, the effects of which can contribute to the limitations in the performance of certain professions of risk. Copyright © 2014 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España, S.L.U. All rights reserved.

  17. Quality criteria for phase change materials selection

    International Nuclear Information System (INIS)

    Vitorino, Nuno; Abrantes, João C.C.; Frade, Jorge R.

    2016-01-01

    Highlights: • Selection criteria of phase change materials for representative applications. • Selection criteria based on reliable solutions for latent heat transfer. • Guidelines for the role of geometry and heat transfer mechanisms. • Performance maps based on PCM properties, operating conditions, size and time scales. - Abstract: Selection guidelines are primary criterion for optimization of materials for specific applications in order to meet simultaneous and often conflicting requirements. This is mostly true for technologies and products required to meet the main societal needs, such as energy. In this case, gaps between supply and demand require strategies for energy conversion and storage, including thermal storage mostly based on phase change materials. Latent heat storage is also very versatile for thermal management and thermal control by allowing high storage density within narrow temperature ranges without strict dependence between stored thermal energy and temperature. Thus, this work addressed the main issues of latent heat storage from a materials selection perspective, based on expected requirements of applications in thermal energy storage or thermal regulation. Representative solutions for the kinetics of latent heat charge/discharge were used to derive optimization guidelines for high energy density, high power, response time (from fast response to thermal inertia), etc. The corresponding property relations were presented in graphical forms for a wide variety of prospective phase change materials, and for wide ranges of operating conditions, and accounting for changes in geometry and mechanisms.

  18. SELECTION CRITERIA FOR LIVER DONATION - A REVIEW

    NARCIS (Netherlands)

    PRUIM, J; KLOMPMAKER, IJ; HAAGSMA, EB; BIJLEVELD, CMA; SLOOFF, MJH

    An overview of the criteria that are currently being used for the selection of liver donors is presented. The validity of the different criteria is discussed. The potential benefits of introducing other modalities is dealt with.

  19. Resin selection criteria for tough composite structures

    Science.gov (United States)

    Chamis, C. C.; Smith, G. T.

    1983-01-01

    Resin selection criteria are derived using a structured methodology consisting of an upward integrated mechanistic theory and its inverse (top-down structured theory). These criteria are expressed in a "criteria selection space" which are used to identify resin bulk properties for improved composite "toughness". The resin selection criteria correlate with a variety of experimental data including laminate strength, elevated temperature effects and impact resistance.

  20. Criteria for onsite transfers of radioactive material

    International Nuclear Information System (INIS)

    Opperman, E.K.; Jackson, E.J.; Eggers, A.G.

    1992-01-01

    A general description of the requirements for making onsite transfers of radioactive material is provided in Chapter 2, along with the required sequencey of activities. Various criteria for package use are identified in Chapters 3-13. These criteria provide protection against undue radiation exposure. Package shielding, containment, and surface contamination requirements are established. Criteria for providing criticality safety are enumerated in Chapter 6. Criteria for providing hazards information are established in Chapter 13. A glossary is provided

  1. Proposed Diagnostic Criteria for Smartphone Addiction

    OpenAIRE

    Lin, Yu-Hsuan; Chiang, Chih-Lin; Lin, Po-Hsien; Chang, Li-Ren; Ko, Chih-Hung; Lee, Yang-Han; Lin, Sheng-Hsuan

    2016-01-01

    Background Global smartphone penetration has led to unprecedented addictive behaviors. The aims of this study are to develop diagnostic criteria of smartphone addiction and to examine the discriminative ability and the validity of the diagnostic criteria. Methods We developed twelve candidate criteria for characteristic symptoms of smartphone addiction and four criteria for functional impairment caused by excessive smartphone use. The participants consisted of 281 college students. Each parti...

  2. Criteria procedure development for tender in construction design

    Directory of Open Access Journals (Sweden)

    Malykha Galina Gennad’evna

    Full Text Available This article deals with the problem of criteria optimization in order to objectively evaluate the experience of an applicant (a project organization and the quality of a design product (project documentation. The methodology to be developed is based on introduction of new evaluation criteria (sub-criteria that in conjunction with the applicable criteria specified by the Law on the Contract System will allow developing the optimal procedure to evaluate competitive bids of the participants in tenders and determining the most appropriate candidate, with whom the contract will be further concluded. The article analyzes the existing criteria and their interaction with each other and describes the specifics of tenders for design in the form of open competition. The list decreases to three criteria, such as "contract price", "quality, functional and environmental characteristics of a procurement facility", "qualification of procurement participants, including availability of financial resources, equipment and other material resources necessary for the execution of the contract material resources, the presence of goodwill, professionals and other employees of a certain experience level". However, in order to upgrade the quality of assurance procedures for the design works to be performed, it was decided to apply new evaluation criteria (sub-criteria components, such as "availability of positive findings of the state out-of-departmental examination that are similar to the subject of competition, on a participant in placement of order", "availability of the certificate on approval of architectural and urban planning decisions that are similar to the subject of competition, on a participant in placement of order", "availability of the permit for the commissioning of facilities that are similar to the subject of competition, on a participant in placement of order", "availability of the contract for designer's supervision with a participant in placement of

  3. 49 CFR 80.15 - Selection criteria.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Selection criteria. 80.15 Section 80.15... § 80.15 Selection criteria. (a) The Secretary shall assign weights as indicated to the following eight selection criteria in evaluating and selecting among eligible projects to receive credit assistance: (1) The...

  4. 28 CFR 34.3 - Selection criteria.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Selection criteria. 34.3 Section 34.3....3 Selection criteria. (a) All individual project applications will, at a minimum, be subject to review based on the extent to which they meet the following general selection criteria: (1) The problem...

  5. 40 CFR 258.40 - Design criteria.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Design criteria. 258.40 Section 258.40... SOLID WASTE LANDFILLS Design Criteria § 258.40 Design criteria. (a) New MSWLF units and lateral... State or as specified in § 258.40(e) for unapproved States. The design must ensure that the...

  6. 30 CFR 104.3 - Pattern criteria.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Pattern criteria. 104.3 Section 104.3 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR PATTERN OF VIOLATIONS PATTERN OF VIOLATIONS § 104.3 Pattern criteria. (a) The criteria of this section shall be used to identify those mines...

  7. 45 CFR 1634.9 - Selection criteria.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Selection criteria. 1634.9 Section 1634.9 Public... FOR GRANTS AND CONTRACTS § 1634.9 Selection criteria. (a) The criteria to be used to select among... key staff; (6) The applicant's knowledge of the various components of the legal services delivery...

  8. Environmental Criteria in the Spanish Public Works Procurement Process.

    Science.gov (United States)

    Fuentes-Bargues, José Luis; González-Cruz, Mª Carmen; González-Gaya, Cristina

    2017-02-18

    Green Public Procurement (GPP) is defined as a process of contracting products, services, and works with the least possible damage to the environment during their life cycle. In order to improve the knowledge about GPP, a study of the use of environmental tendering criteria in the Spanish public construction sector has been performed. The results of this study show that the use of environmental criteria in Spanish public sector construction procurement is low in comparison to a certain group of countries, known as "Green 7", in the European Union. Environmental criteria is the fourth criterion in importance, but its weight in the global of the process is much lower than other criteria such as price, memory of the construction process and the delivery time. National administrations use environmental criteria more frequently because they have more resources and staff training about environmental issues. Environmental criteria are more used in the tendering of civil projects and works whose budget exceeds ten million euro due to the environmental impact of these kind and/or size of projects.

  9. New diagnostic criteria for fibromyalgia: Here to stay?

    Science.gov (United States)

    Moyano, Sebastián; Kilstein, Jorge Guillermo; Alegre de Miguel, Cayetano

    2015-01-01

    To assess the percentage of patients that fulfill the American College of Rheumatology (ACR) 1990 as well as the ACR 2010 classification criteria, to evaluate whether there is a correlation between tender points and the Widespread Pain Index (WPI) as well as signs and symptoms that predict a fibromyalgia (FM) subtype and to identify those which have greater impact on functioning. We performed a cross-sectional comparative study of 206 patients with previous clinical diagnosis of FM. The studied variables were age, sex, years of disease, tender points, control points, WPI, Symptom Severity Score, subtype of FM, presence of other rheumatic disorders and the Fibromyalgia Impact Questionnaire (FIQ) score. The new diagnostic criteria of FM correctly classified 87,03% of patients who satisfied the ACR 1990 criteria. Both criteria were equally effective in assessing the impact of the disease. FM had a severe impact on the quality of life in 74,87% of patients. Somatoform disorder was the predominant subtype. Hyperalgesic FM had a significantly lower FIQ score than the somatoform disorder and depressive subtypes. The ACR 2010 criteria are a simple evaluation tool to use in the primary care setting, that incorporate both peripheral pain and somatic symptoms. New and old criteria should coexist; they enable a major comprehension and ease the management of this prevalent disease. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

  10. Environmental Criteria in the Spanish Public Works Procurement Process

    Directory of Open Access Journals (Sweden)

    José Luis Fuentes-Bargues

    2017-02-01

    Full Text Available Green Public Procurement (GPP is defined as a process of contracting products, services, and works with the least possible damage to the environment during their life cycle. In order to improve the knowledge about GPP, a study of the use of environmental tendering criteria in the Spanish public construction sector has been performed. The results of this study show that the use of environmental criteria in Spanish public sector construction procurement is low in comparison to a certain group of countries, known as “Green 7”, in the European Union. Environmental criteria is the fourth criterion in importance, but its weight in the global of the process is much lower than other criteria such as price, memory of the construction process and the delivery time. National administrations use environmental criteria more frequently because they have more resources and staff training about environmental issues. Environmental criteria are more used in the tendering of civil projects and works whose budget exceeds ten million euro due to the environmental impact of these kind and/or size of projects.

  11. Review of constitutive models and failure criteria for concrete

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Jeong Moon; Choun, Young Sun [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-03-01

    The general behavior, constitutive models, and failure criteria of concrete are reviewed. The current constitutive models for concrete cannot satisfy all of mechanical behavior of concrete. Among several constitutive models, damage models are recommended to describe properly the structural behavior of concrete containment buildings, because failure modes and post-failure behavior are important in containment buildings. A constitutive model which can describe the concrete behavior in tension is required because the containment buildings will reach failure state due to ultimate internal pressure. Therefore, a thorough study on the behavior and models under tension stress state in concrete and reinforced concrete has to be performed. There are two types of failure criteria in containment buildings: structural failure criteria and leakage failure criteria. For reinforced or prestressed concrete containment buildings, concrete cracking does not mean the structural failure of containment building because the reinforcement or post-tensioning system is able to resist tensile stress up to yield stress. Therefore leakage failure criteria will be prior to structural failure criteria, and a strain failure criterion for concrete has to be established. 120 refs., 59 figs., 1 tabs. (Author)

  12. 78 FR 7820 - Notice of Intelligent Mail Indicia Performance Criteria

    Science.gov (United States)

    2013-02-04

    ... Replacement Document Volume I--PES Requirements. Provides the PES industry and test laboratories with detailed... human-readable and machine readable, for all postage evidence produced by a PES. This volume also...

  13. Performance criteria for graph clustering and Markov cluster experiments

    NARCIS (Netherlands)

    S. van Dongen

    2000-01-01

    textabstractIn~[1] a cluster algorithm for graphs was introduced called the Markov cluster algorithm or MCL~algorithm. The algorithm is based on simulation of (stochastic) flow in graphs by means of alternation of two operators, expansion and inflation. The results in~[2] establish an intrinsic

  14. Performance of modified WHO presumptive criteria for diagnosis of ...

    African Journals Online (AJOL)

    Background: Making a diagnosis of HIV infection in children aged less than 18 months remains a challenge in low resource settings like Zambia due to the limited availability of gold standard testing with HIV DNA PCR. Clinicians in rural areas have to depend on clinical diagnosis to start HAART asthey wait for the dry blood ...

  15. Potential Performance Criteria for Combat Ration Packs - Texture Profile Analysis

    Science.gov (United States)

    2014-11-01

    biscuit, apricot muesli bar, tropical muesli bar, forest fruits muesli bar, chocolate pudding, golden pudding and fruit pudding. • Dairy products ...were canned products with a semi-solid texture and were semi-moist product . Chocolate and golden puddings were self-saucing with a homogeneous matrix...TPA are discussed. UNCLASSIFIED UNCLASSIFIED 3. Significant changes in texture were observed for golden and chocolate self-saucing puddings and

  16. 36 CFR 1194.31 - Functional performance criteria.

    Science.gov (United States)

    2010-07-01

    ... important for the use of a product, at least one mode of operation and information retrieval shall be provided in an enhanced auditory fashion, or support for assistive hearing devices shall be provided. (e...

  17. Optimizing the design of very high power, high performance converters

    International Nuclear Information System (INIS)

    Edwards, R.J.; Tiagha, E.A.; Ganetis, G.; Nawrocky, R.J.

    1980-01-01

    This paper describes how various technologies are used to achieve the desired performance in a high current magnet power converter system. It is hoped that the discussions of the design approaches taken will be applicable to other power supply systems where stringent requirements in stability, accuracy and reliability must be met

  18. Operating experience and design criteria of sodium valves

    International Nuclear Information System (INIS)

    Markford, D.

    1974-01-01

    The information presented refers to sodium valve development for KNK and SNR-300 as well as for sodium test facilities on the INTERATOM site at Bensberg. Well in advance of KNK-I a number of sodium test facilities have been operated containing small and medium size valves of different design and manufacturer. The more stringent requirements for long range safe and reliable operation in KNK-I put forth a development program for the main primary and secondary circuit sodium valves. Operational experience gave rise to modification of the stem seal arrangement mainly, so KNK-II (which is the fast core for KNK reactor) will be run with modified sodium valves. Main pipe diameters in SNR-300 are in the range of 600 mm. Valve designs with rising shafts would require excessive space in the primary circuit cavities, therefore efforts have been directed towards introduction of different type valves. Due to the requirements of after-heat-removal a valve type with control capability had to be chosen. A special design of butterfly valves was selected for the primary and secondary circuits of SNR-300. The development and tests performed with this type of valve are described. In the field of small sodium valves, tests with a 50 mm diameter freeze-seal valve are reported, and the current status of bellows-seal-valves to be inserted into SNR-300 is discussed. (U.S.)

  19. Integral Criteria for Measuring the Quality of Teacher Evaluation

    Directory of Open Access Journals (Sweden)

    Olga Navickienė

    2012-07-01

    Full Text Available Purpose—To construct the knowledge evaluation quality integral criteria, which allows to ascertain whether the different teachers properly assess the students’ knowledge. The criteria has been tested setting up the educational experiment and examining the six mathematics lecturers’ assessments.Design/methodology/approach—This research involved the Mykolas Romeris University students of Public Administration degree second year and Management of Organizations degree first year. The test questions for students were designed using the mathematical knowledge assessment information system, which allows for closed-ended mathematical test, to obtain statistical data about test takers, to perform quality analysis of the test; in the middle and the end of the semester.Findings—The construction technique for the evaluation quality criteria of the students’ working results assessment, which were performed by six different lecturers, during practical trainings, seminars, laboratory and other sessions is proposed in this article.Research limitations/implications—The constructed evaluation criteria is universal: it does not depend on the particular subject; it can be applied to several groups, courses or lecturers. It depends on three calculated indicators I, S, K, which show in two ways obtained estimates of the measured information compatibility of degrees, marks matching and correlation terms.Practical implications—The integral criteria has been tested examining the six mathematics lecturers’ assessments.Originality/Value—Constructing the criteria have been used the educational measurement models of authors of this article and other researchers, however its’ connection to general (integral criteria, best of authors’ knowledge, is original and have not be researched before.Keywords: knowledge evaluation, quality of teacher evaluation, evaluation of teachers, mathematical modeling.Research type: research paper.

  20. 5 CFR 551.207 - Professional exemption criteria.

    Science.gov (United States)

    2010-01-01

    ... criteria. To qualify for the professional exemption, an employee's primary duty must be the performance of..., originality or talent in a recognized field of artistic or creative endeavor. Learned professionals, creative professionals, and computer employees are described in §§ 551.208, 551.209, and 551.210, respectively. ...

  1. 42 CFR 483.128 - PASARR evaluation criteria.

    Science.gov (United States)

    2010-10-01

    ... (including Alzheimer's Disease or a related disorder); or (ii) A non-primary diagnosis of dementia without a... criteria. (a) Level I: Identification of individuals with MI or MR. The State's PASARR program must... specialized services are needed. The State's performance of the Level I identification function must provide...

  2. Regulatory analysis on criteria for the release of patients administered radioactive material

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, S.; McGuire, S.A. [Nuclear Regulatory Commission, Washington, DC (United States). Div. of Regulatory Applications; Behling, U.H.; Behling, K.; Goldin, D. [Cohen (S.) and Associates, Inc., McLean, VA (United States)

    1994-05-01

    The Nuclear Regulatory Commission (NRC) has received two petitions to amend its regulations in 10 CFR Parts 20 and 35 as they apply to doses received by members of the public exposed to patients released from a hospital after they have been administered radioactive material. While the two petitions are not identical they both request that the NRC establish a dose limit of 5 millisieverts (0.5 rem) per year for individuals exposed to patients who have been administered radioactive materials. This Regulatory Analysis evaluates three alternatives. Alternative 1 is for the NRC to amend its patient release criteria in 10 CFR 35.75 to use the more stringent dose limit of 1 millisievert per year in 10 CFR 20.1301(a) for its patient release criteria. Alternative 2 is for the NRC to continue using the existing patient release criteria in 10 CFR 35.75 of 1,110 megabecquerels of activity or a dose rate at one meter from the patient of 0.05 millisievert per hour. Alternative 3 is for the NRC to amend the patient release criteria in 10 CFR 35.75 to specify a dose limit of 5 millisieverts for patient release. The evaluation indicates that Alternative 1 would cause a prohibitively large increase in the national health care cost from retaining patients in a hospital longer and would cause significant personal and psychological costs to patients and their families. The choice of Alternatives 2 or 3 would affect only thyroid cancer patients treated with iodine-131. For those patients, Alternative 3 would result in less hospitalization than Alternative 2. Alternative 3 has a potential decrease in national health care cost of $30,000,000 per year but would increase the potential collective dose from released therapy patients by about 2,700 person-rem per year, mainly to family members.

  3. Regulatory analysis on criteria for the release of patients administered radioactive material

    International Nuclear Information System (INIS)

    Schneider, S.; McGuire, S.A.

    1994-05-01

    The Nuclear Regulatory Commission (NRC) has received two petitions to amend its regulations in 10 CFR Parts 20 and 35 as they apply to doses received by members of the public exposed to patients released from a hospital after they have been administered radioactive material. While the two petitions are not identical they both request that the NRC establish a dose limit of 5 millisieverts (0.5 rem) per year for individuals exposed to patients who have been administered radioactive materials. This Regulatory Analysis evaluates three alternatives. Alternative 1 is for the NRC to amend its patient release criteria in 10 CFR 35.75 to use the more stringent dose limit of 1 millisievert per year in 10 CFR 20.1301(a) for its patient release criteria. Alternative 2 is for the NRC to continue using the existing patient release criteria in 10 CFR 35.75 of 1,110 megabecquerels of activity or a dose rate at one meter from the patient of 0.05 millisievert per hour. Alternative 3 is for the NRC to amend the patient release criteria in 10 CFR 35.75 to specify a dose limit of 5 millisieverts for patient release. The evaluation indicates that Alternative 1 would cause a prohibitively large increase in the national health care cost from retaining patients in a hospital longer and would cause significant personal and psychological costs to patients and their families. The choice of Alternatives 2 or 3 would affect only thyroid cancer patients treated with iodine-131. For those patients, Alternative 3 would result in less hospitalization than Alternative 2. Alternative 3 has a potential decrease in national health care cost of $30,000,000 per year but would increase the potential collective dose from released therapy patients by about 2,700 person-rem per year, mainly to family members

  4. Investigation of Sustainable Housing Criteria

    Directory of Open Access Journals (Sweden)

    roshanfekr Somayeh

    2016-01-01

    Full Text Available Recently, much attention has been paid to sustainable development in cities. The quality of human life is directly related to environmental quality. Because many people live in cities as a place of social, economic and cultural relationships, certain issues such as environmental crises, energy, air and noise pollution and traffic jams are some of the factors that can alter the quality of human life. Therefore, in order to improve the quality of human life, attention to sustainable development (or sustainability in cities is proposed. Sustainable building has a comprehensive significance that begins with the conception of negative and positive impacts on the environment. Several descriptions of sustainable or green buildings have been created; however, they all pursue one goal, which is to create sustainable urban developments and protection of the environment. The quality of indoor environments, materials, and energy consumption, water usage, the impact of building construction processes and building maintenance are some of the factors that affect the environment and sustainability. Sustainable building is an attempt to relieve the minus impacts on the environment that occur during a building’s lifetime. This research investigates the important factors that have relevance to green buildings and introduces several criteria of sustainable housing.

  5. Infecções relacionadas à assistência a saúde baseada em critérios internacionais, realizada em unidade neonatal de cuidados progressivos de referência de Belo Horizonte, MG Notification of healthcare associated infections based on international criteria performed in a reference neonatal progressive care unity in Belo Horizonte, MG

    Directory of Open Access Journals (Sweden)

    Roberta Maia de Castro Romanelli

    2013-03-01

    Full Text Available OBJETIVO: Descrever a ocorrência de infecções relacionadas à assistência à saúde em uma unidade neonatal de serviço público de referência em Belo Horizonte, MG, baseando-se em critérios internacionais. MÉTODOS: Trata-se de estudo descritivo, realizado por busca ativa, na Unidade Neonatal de Cuidados Progressivos do Hospital das Clínicas da Universidade Federal de Minas Gerais (HC/UFMG, de 2008 a 2009. A notificação de infecções baseou-se nos critérios do National Healthcare Safety Network (NHSN. O banco de dados e análise foi realizado em programa interno do serviço. RESULTADOS: Foram notificados 325 episódios de infecção nos recém-nascidos, com densidade de incidência de 22,8/1.000 pacientes-dia e incidência proporcional geral de infecção de 36,7%. A sepse foi a principal infecção (62,5% notificada. A densidade de incidência de infecções foi maior em neonatos com peso menor que 750g (42,4/1.000 pacientes-dia. Observou-se 18,15 episódios de Sepse Relacionada a Cateter/1.000 Cateter Venoso Central-dia e 19,29/1.000 episódios de Sepse Relacionada a Cateter Umbilical/1.000 Cateter umbilical-dia. Em 122 (37,5% casos de infecção notificada houve isolamento de microorganismos, predominando Staphylococcus coagulase negativo e Staphylococcus aureus (51 casos. A mortalidade e letalidade foram 4,3% e 17,12%, respectivamente. CONCLUSÃO: A utilização de critérios padronizados para notificação de infecções é necessária para a construção de indicadores em neonatologia, que são escassos no país e ressaltam a necessidade de avaliação dos critérios nacionais propostos pela Agencia Nacional de Vigilância Sanitária (ANVISA. OBJECTIVE: To describe occurence of Healthcare Related Infections in a neonatal unit of public reference service in Belo Horizonte-MG, based on international criteria. METHODS: This is a descriptive study, performed by active searching, in the Progressive Care Unit Neonatal Hospital das

  6. Evaluation of Web-Based Training Courses by Means of Criteria on Learning Support

    Energy Technology Data Exchange (ETDEWEB)

    Geisser, R.; Keefer, F.; Schoenfelder, C.

    2015-07-01

    In recent years, due to the widespread use of digital media and the internet, more and more traditional education and training measures have been replaced or enhanced by elearning. In the context of the nuclear industry, however, with its stringent demand for well qualified and motivated human resources, it is very important to know to what extent these new learning formats will contribute to effective education and training. In cooperation with AREVA and within the scope of a master thesis, it was first investigated as to which factors greatly support the effectiveness of learning by using digital media, from a learner’s point of view in particular. Then, several criteria were developed that could be used to evaluate web based training courses. Next, these criteria were applied to three courses that have already been implemented at AREVA for different target groups and training objectives. The investigation has shown that factors which support the effectiveness of learning are not well known and not systematically applied in the training development process. Consequently, the success of training implementation depends to a great extent on the competence of external suppliers for e-learning programming. (Author)

  7. Evaluation of Web-Based Training Courses by Means of Criteria on Learning Support

    International Nuclear Information System (INIS)

    Geisser, R.; Keefer, F.; Schoenfelder, C.

    2015-01-01

    In recent years, due to the widespread use of digital media and the internet, more and more traditional education and training measures have been replaced or enhanced by elearning. In the context of the nuclear industry, however, with its stringent demand for well qualified and motivated human resources, it is very important to know to what extent these new learning formats will contribute to effective education and training. In cooperation with AREVA and within the scope of a master thesis, it was first investigated as to which factors greatly support the effectiveness of learning by using digital media, from a learner’s point of view in particular. Then, several criteria were developed that could be used to evaluate web based training courses. Next, these criteria were applied to three courses that have already been implemented at AREVA for different target groups and training objectives. The investigation has shown that factors which support the effectiveness of learning are not well known and not systematically applied in the training development process. Consequently, the success of training implementation depends to a great extent on the competence of external suppliers for e-learning programming. (Author)

  8. Proposed Diagnostic Criteria for Smartphone Addiction.

    Directory of Open Access Journals (Sweden)

    Yu-Hsuan Lin

    Full Text Available Global smartphone penetration has led to unprecedented addictive behaviors. The aims of this study are to develop diagnostic criteria of smartphone addiction and to examine the discriminative ability and the validity of the diagnostic criteria.We developed twelve candidate criteria for characteristic symptoms of smartphone addiction and four criteria for functional impairment caused by excessive smartphone use. The participants consisted of 281 college students. Each participant was systematically assessed for smartphone-using behaviors by psychiatrist's structured diagnostic interview. The sensitivity, specificity, and diagnostic accuracy of the candidate symptom criteria were analyzed with reference to the psychiatrists' clinical global impression. The optimal model selection with its cutoff point of the diagnostic criteria differentiating the smartphone addicted subjects from non-addicted subjects was then determined by the best diagnostic accuracy.Six symptom criteria model with optimal cutoff point were determined based on the maximal diagnostic accuracy. The proposed smartphone addiction diagnostic criteria consisted of (1 six symptom criteria, (2 four functional impairment criteria and (3 exclusion criteria. Setting three symptom criteria as the cutoff point resulted in the highest diagnostic accuracy (84.3%, while the sensitivity and specificity were 79.4% and 87.5%, respectively. We suggested determining the functional impairment by two or more of the four domains considering the high accessibility and penetration of smartphone use.The diagnostic criteria of smartphone addiction demonstrated the core symptoms "impaired control" paralleled with substance related and addictive disorders. The functional impairment involved multiple domains provide a strict standard for clinical assessment.

  9. Proposed Diagnostic Criteria for Smartphone Addiction

    Science.gov (United States)

    Lin, Yu-Hsuan; Chiang, Chih-Lin; Lin, Po-Hsien; Chang, Li-Ren; Ko, Chih-Hung; Lee, Yang-Han

    2016-01-01

    Background Global smartphone penetration has led to unprecedented addictive behaviors. The aims of this study are to develop diagnostic criteria of smartphone addiction and to examine the discriminative ability and the validity of the diagnostic criteria. Methods We developed twelve candidate criteria for characteristic symptoms of smartphone addiction and four criteria for functional impairment caused by excessive smartphone use. The participants consisted of 281 college students. Each participant was systematically assessed for smartphone-using behaviors by psychiatrist’s structured diagnostic interview. The sensitivity, specificity, and diagnostic accuracy of the candidate symptom criteria were analyzed with reference to the psychiatrists’ clinical global impression. The optimal model selection with its cutoff point of the diagnostic criteria differentiating the smartphone addicted subjects from non-addicted subjects was then determined by the best diagnostic accuracy. Results Six symptom criteria model with optimal cutoff point were determined based on the maximal diagnostic accuracy. The proposed smartphone addiction diagnostic criteria consisted of (1) six symptom criteria, (2) four functional impairment criteria and (3) exclusion criteria. Setting three symptom criteria as the cutoff point resulted in the highest diagnostic accuracy (84.3%), while the sensitivity and specificity were 79.4% and 87.5%, respectively. We suggested determining the functional impairment by two or more of the four domains considering the high accessibility and penetration of smartphone use. Conclusion The diagnostic criteria of smartphone addiction demonstrated the core symptoms “impaired control” paralleled with substance related and addictive disorders. The functional impairment involved multiple domains provide a strict standard for clinical assessment. PMID:27846211

  10. Maintainability design criteria for packaging of spacecraft replaceable electronic equipment.

    Science.gov (United States)

    Kappler, J. R.; Folsom, A. B.

    1972-01-01

    Maintainability must be designed into long-duration spacecraft and equipment to provide the required high probability of mission success with the least cost and weight. The ability to perform repairs quickly and easily in a space environment can be achieved by imposing specific maintainability design criteria on spacecraft equipment design and installation. A study was funded to investigate and define design criteria for electronic equipment that would permit rapid removal and replacement in a space environment. The results of the study are discussed together with subsequent simulated zero-g demonstration tests of a mockup with new concepts for packaging.

  11. Photovoltaic module certification/laboratory accreditation criteria development

    Energy Technology Data Exchange (ETDEWEB)

    Osterwald, C.R. [National Renewable Energy Lab., Golden, CO (United States); Hammond, R.L.; Wood, B.D.; Backus, C.E.; Sears, R.L. [Arizona State Univ., Tempe, AZ (United States); Zerlaut, G.A. [SC-International Inc., Phoenix, AZ (United States); D`Aiello, R.V. [RD Associates, Tempe, AZ (United States)

    1995-04-01

    This document provides an overview of the structure and function of typical product certification/laboratory accreditation programs. The overview is followed by a model program which could serve as the basis for a photovoltaic (PV) module certification/laboratory accreditation program. The model covers quality assurance procedures for the testing laboratory and manufacturer, third-party certification and labeling, and testing requirements (performance and reliability). A 30-member Criteria Development Committee was established to guide, review, and reach a majority consensus regarding criteria for a PV certification/laboratory accreditation program. Committee members represented PV manufacturers, end users, standards and codes organizations, and testing laboratories.

  12. Multi-material topology design of laminates with strength criteria

    DEFF Research Database (Denmark)

    Lund, Erik

    2012-01-01

    The objective of this paper is to present a novel approach for multi-material topology optimization of laminated composite structures where strength constraints are taken into account together with other global structural performance measures. The topology design problem considered contains very...... many design variables, and when strength criteria are included in the problem, a very large number of criteria functions must be considered in the optimization problem to be solved. Thus, block aggregation methods are introduced, such that global strength measures are obtained. These formulations...... are illustrated for multi-material laminated design problems where the maximum failure index is minimized while compliance and mass constraints are taken into account....

  13. Liver Transplantation: Evolving Patient Selection Criteria

    Directory of Open Access Journals (Sweden)

    Andy S Yu

    2001-01-01

    Full Text Available The widespread recognition of the success of liver transplantation as a treatment for most types of acute and chronic liver failure has led to increased referrals for transplantation in the setting of a relatively fixed supply of cadaver donor organs. These events have led to a marked lengthening of the waiting time for liver transplantation, resulting in increased deaths of those on the waiting list and sicker patients undergoing transplantation. Nearly 5000 liver transplantations were performed in the United States in 2000, while the waiting list grew to over 17,000 patients. The mounting disparity between the number of liver transplant candidates and the limited supply of donor organs has led to reassessment of the selection and listing criteria for liver transplantation, as well as revision of organ allocation and distribution policies for cadaver livers. The development of minimal listing criteria for patients with chronic liver disease based on a specific definition for decompensation of cirrhosis has facilitated the more uniform listing of patients at individual centres across the United States. The United Network for Organ Sharing, under pressure from transplant professionals, patient advocacy groups and the federal government, has continuously revised allocation and distribution policies based on the ethical principles of justice for the individual patient versus optimal utility of the limited organ supply available annually. Beginning in 2002, it is likely that the Model for End-stage Liver Disease (MELD score will be implemented to determine disease severity and direct donor organs to the sickest patients rather than to those with the longest waiting times.

  14. Validation criteria of an internal dosimetry laboratory in vivo

    International Nuclear Information System (INIS)

    Alfaro L, M. de las M.

    2014-10-01

    People working with radioactive materials, under certain circumstances (e.g. not using the proper protective equipment, an incident not covered, etc.) could be incorporated into the body. The radiation protection programs include direct measurement methods -in vivo- or indirect -in vitro- or both, to know that radioactive material is incorporated into the body. The monitoring measurements of internal contamination or (Radio-bioassay) are carried out with the purpose of determining the amount of radioactive material incorporated in the body; estimate the effective dose and committed dose; management administration of radiation protection; appropriate medical management; and to provide the data necessary for the legal requirements and the preservation of records. The measurement methods used in the monitoring of internal contamination must be validated by the combination of the following processes: calibration, using standards reference materials and/or simulators; execute systematic research, using control samples; and intercomparison between laboratories and performance tests. In this paper the validation criteria of an internal dosimetry laboratory in vivo are presented following the information provided by the standard ANSI N13-30-1996 and ISO/TEC 17025-2005 as are the criteria of facilities, staff training, interpretation of measurements, performance criteria for monitoring of internal contamination in vivo, results reporting and records retention. Thereby we achieve standardized quantitative performance criteria of truthfulness, accuracy and detection limit and a consensus on statistical definitions to establish the validation plan of a monitoring laboratory of internal contamination in vivo. (Author)

  15. AAPT Diagnostic Criteria for Central Neuropathic Pain

    DEFF Research Database (Denmark)

    Widerstrom-Noga, Eva; Loeser, John D.; Jensen, Troels Staehelin

    2017-01-01

    ) initiative, invited a working group to develop diagnostic criteria for central neuropathic pain. The criteria for central neuropathic pain that were developed expand upon existing criteria for neuropathic pain and the International Classification of Diseases 11th Revision draft criteria to ensure consistency......: The AAPT chronic central neuropathic pain taxonomy provides a classification for central pain associated with spinal cord injury, stroke, and multiple sclerosis. The diagnostic criteria are organized according to the AAPT multidimensional framework, specifically: 1) core diagnostic criteria, 2) common......Central neuropathic pain, which is pain caused by a lesion or disease of the central somatosensory nervous system, is a serious consequence of spinal cord injury, stroke, multiple sclerosis, and other conditions affecting the central nervous system. A collaborative effort between the Analgesic...

  16. Assessment Criteria of Bentonite Binding Properties

    Directory of Open Access Journals (Sweden)

    S. Żymankowska-Kumon

    2012-09-01

    Full Text Available The criteria, with which one should be guided at the assessment of the binding properties of bentonites used for moulding sands, areproposed in the paper. Apart from the standard parameter which is the active bentonite content, the unrestrained growth indicator should be taken into account since it seems to be more adequate in the estimation of the sand compression strength. The investigations performed for three kinds of bentonites, applied in the Polish foundry plants, subjected to a high temperature influences indicate, that the pathway of changes of the unrestrained growth indicator is very similar to the pathway of changes of the sand compression strength. Instead, the character of changes of the montmorillonite content in the sand in dependence of the temperature is quite different. The sand exhibits the significant active bentonite content, and the sand compression strength decreases rapidly. The montmorillonite content in bentonite samples was determined by the modern copper complex method of triethylenetetraamine (Cu(II-TET. Tests were performed for bentonites and for sands with those bentonites subjected to high temperatures influences in a range: 100-700ºC.

  17. Selection criteria of residents for residency programs in Kuwait.

    Science.gov (United States)

    Marwan, Yousef; Ayed, Adel

    2013-01-19

    In Kuwait, 21 residency training programs were offered in the year 2011; however, no data is available regarding the criteria of selecting residents for these programs. This study aims to provide information about the importance of these criteria. A self-administered questionnaire was used to collect data from members (e.g. chairmen, directors, assistants …etc.) of residency programs in Kuwait. A total of 108 members were invited to participate. They were asked to rate the importance level (scale from 1 to 5) of criteria that may affect the acceptance of an applicant to their residency programs. Average scores were calculated for each criterion. Of the 108 members invited to participate, only 12 (11.1%) declined to participate. Interview performance was ranked as the most important criteria for selecting residents (average score: 4.63/5.00), followed by grade point average (average score: 3.78/5.00) and honors during medical school (average score: 3.67/5.00). On the other hand, receiving disciplinary action during medical school and failure in a required clerkship were considered as the most concerning among other criteria used to reject applicants (average scores: 3.83/5.00 and 3.54/5.00 respectively). Minor differences regarding the importance level of each criterion were noted across different programs. This study provided general information about the criteria that are used to accept/reject applicants to residency programs in Kuwait. Future studies should be conducted to investigate each criterion individually, and to assess if these criteria are related to residents' success during their training.

  18. INFLUENCE OF OPERABILITY CRITERIA LIMITING VALUES ON SHIP SPEED

    Directory of Open Access Journals (Sweden)

    Jasna Prpić-Oršić

    2016-09-01

    Full Text Available When the ship is caught in heavy seas, there are two manoeuvres that the shipmaster can undertake to avoid excessive ship motion and hull damage: changing course or voluntary speed reduction. This paper presents a study of the effect of the various voluntary speed reduction criteria to attainable speed of ship on seaway. The speed loss is calculated by taking into account wind and wave effect on ship speed, the engine and propeller performance in actual seas as well as the mass inertia of the ship. The attainable ship speed for ship in head, following and beam waves by accounting for voluntary speed reduction is estimated for various significant wave height. The criteria of slamming, deck wetness, propeller emergence, excessive accelerations and roll are taken into account. The impact of variations of the limiting values of certain criteria due to which the captain intentionally reduces the ship speed is analysed and discussed.

  19. [Primary childhood vasculitis new classification criteria

    DEFF Research Database (Denmark)

    Herlin, T.; Nielsen, Susan

    2008-01-01

    Primary vasculitis is seen in both adults and children, but some of the diseases like Kawasaki disease occur primarily in children. The Chapel Hill Classification Criteria for primary vasculitis refers to the size of vessels but has not been validated in children. Recently, new criteria for the c......Primary vasculitis is seen in both adults and children, but some of the diseases like Kawasaki disease occur primarily in children. The Chapel Hill Classification Criteria for primary vasculitis refers to the size of vessels but has not been validated in children. Recently, new criteria...

  20. News: Good chemical manufacturing process criteria

    Science.gov (United States)

    This news column covers topics relating to manufacturing criteria, machine to machine technology, novel process windows, green chemistry indices, business resilience, immobilized enzymes, and Bt crops.

  1. 2012 Provisional classification criteria for polymyalgia rheumatica

    DEFF Research Database (Denmark)

    Dasgupta, Bhaskar; Cimmino, Marco A; Kremers, Hilal Maradit

    2012-01-01

    The objective of this study was to develop European League Against Rheumatism/American College of Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new-onset PMR and 169 non-PMR compa......The objective of this study was to develop European League Against Rheumatism/American College of Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new-onset PMR and 169 non...

  2. Applicability of the Appropriate use Criteria for Myocardial Perfusion Scintigraphy

    International Nuclear Information System (INIS)

    Oliveira, Anderson de; Rezende, Maria Fernanda; Corrêa, Renato; Mousinho, Rodrigo; Azevedo, Jader Cunha; Miranda, Sandra Marina; Oliveira, Aline Ribeiro; Gutterres, Ricardo Fraga; Mesquita, Evandro Tinoco; Mesquita, Cláudio Tinoco

    2014-01-01

    Appropriateness Criteria for nuclear imaging exams were created by American College of Cardiology (ACC) e American Society of Nuclear Cardiology (ASNC) to allow the rational use of tests. Little is known whether these criteria have been followed in clinical practice. To evaluate whether the medical applications of myocardial perfusion scintigraphy (MPS) in a private nuclear medicine service of a tertiary cardiology hospital were suitable to the criteria of indications proposed by the American medical societies in 2005 and 2009 and compare the level of indication of both. We included records of 383 patients that underwent MPS, November 2008 up to February 2009. Demographic characteristics, patient's origin, coronary risk factors, time of medical graduation and appropriateness criteria of medical applications were studied. The criteria were evaluated by two independent physicians and, in doubtful cases, defined by a medical expert in MPS. Mean age was 65 ± 12 years. Of the 367 records reviewed, 236 (64.3%) studies were performed in men and 75 (20.4%) were internee. To ACC 2005, 255 (69.5%) were considered appropriate indication and 13 (3.5%) inappropriate. With ACC 2009, 249 (67.8%) were considered appropriate indications and 13 (5.2%) inappropriate. We observed a high rate of adequacy of medical indications for MPS. Compared to the 2005 version, 2009 did not change the results

  3. Refinement of pointwise linear regression criteria for determining glaucoma progression.

    Science.gov (United States)

    Kummet, Colleen M; Zamba, K D; Doyle, Carrie K; Johnson, Chris A; Wall, Michael

    2013-09-19

    A variety of pointwise linear regression (PLR) criteria have been proposed for determining glaucomatous visual field progression. However, alternative PLR criteria have only been assessed on a limited basis. The purpose of this study was to evaluate a range of PLR slope and significance criteria to define a clinically useful progression decision rule for longitudinal visual field examinations. Visual field data for each of 140 eyes (one per participant among 96 cases and 44 controls) were evaluated using the Humphrey Field Analyzer II program 24-2 Swedish interactive thresholding algorithm standard test strategy and Goldmann size III stimuli. The pointwise linear regression A2 (PLRA2) method was used to analyze the data, which included nine visual field examinations performed every 6 months for 4 years. Data from the Ocular Hypertension Treatment Study (OHTS) were used to validate the decision rule. Several slope criteria produced specificities of 0.90 or higher, particularly slope criteria of less than -1.2 dB/y. The use of the slope criterion less than -1.2 dB/y at a significance level of P refined by requiring a stricter slope criterion such as less than -1.2 dB/y and relaxing the significance criterion to P < 0.04. Increasing the hit rate of PLR will be useful for early detection and treatment of glaucoma.

  4. Criteria for Determination of Material Control and Accountability System Effectiveness

    International Nuclear Information System (INIS)

    John Wright

    2008-01-01

    The Nevada Test Site (NTS) is a test bed for implementation of the Safeguards First Principles Initiative (SFPI), a risk-based approach to Material Control and Accountability (MC and A) requirements. The Comprehensive Assessment of Safeguards Strategies (COMPASS) model is used to determine the effectiveness of MC and A systems under SFPI. Under this model, MC and A is divided into nine primary elements. Each element is divided into sub-elements. Then each sub-element is assigned two values, effectiveness and contribution, that are used to calculate the rating. Effectiveness is a measure of subelement implementation and how well it meets requirements. Contribution is a relative measure of the importance, and functions as a weighting factor. The COMPASS model provides the methodology for calculation of sub-element and element ratings, but not the actual criteria. Each site must develop its own criteria. For the rating to be meaningful, the effectiveness criteria must be objective and based on explicit, measurable criteria. Contribution (weights) must reflect the importance within the MC and A program. This paper details the NTS approach to system effectiveness and contribution values, and will cover the following: the basis for the ratings, an explanation of the contribution 'weights', and the objective, performance based effectiveness criteria. Finally, the evaluation process will be described

  5. Anticipating Potential Waste Acceptance Criteria for Defense Spent Nuclear Fuel

    International Nuclear Information System (INIS)

    Rechard, R.P.; Lord, M.E.; Stockman, C.T.; McCurley, R.D.

    1997-01-01

    The Office of Environmental Management of the U.S. Department of Energy is responsible for the safe management and disposal of DOE owned defense spent nuclear fuel and high level waste (DSNF/DHLW). A desirable option, direct disposal of the waste in the potential repository at Yucca Mountain, depends on the final waste acceptance criteria, which will be set by DOE's Office of Civilian Radioactive Waste Management (OCRWM). However, evolving regulations make it difficult to determine what the final acceptance criteria will be. A method of anticipating waste acceptance criteria is to gain an understanding of the DOE owned waste types and their behavior in a disposal system through a performance assessment and contrast such behavior with characteristics of commercial spent fuel. Preliminary results from such an analysis indicate that releases of 99Tc and 237Np from commercial spent fuel exceed those of the DSNF/DHLW; thus, if commercial spent fuel can meet the waste acceptance criteria, then DSNF can also meet the criteria. In large part, these results are caused by the small percentage of total activity of the DSNF in the repository (1.5%) and regulatory mass (4%), and also because commercial fuel cladding was assumed to provide no protection

  6. Applicability of the Appropriate use Criteria for Myocardial Perfusion Scintigraphy

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Anderson de [Universidade Federal Fluminense - UFF, Niterói, RJ (Brazil); Comissão Nacional de Energia Nuclear - CNEN (Brazil); Rezende, Maria Fernanda [Universidade Federal Fluminense - UFF, Niterói, RJ (Brazil); Hospital Pró-Cardíaco, Rio de Janeiro, RJ (Brazil); Corrêa, Renato; Mousinho, Rodrigo [Hospital Pró-Cardíaco, Rio de Janeiro, RJ (Brazil); Azevedo, Jader Cunha [Universidade Federal Fluminense - UFF, Niterói, RJ (Brazil); Hospital Pró-Cardíaco, Rio de Janeiro, RJ (Brazil); Miranda, Sandra Marina; Oliveira, Aline Ribeiro [Universidade Federal Fluminense - UFF, Niterói, RJ (Brazil); Gutterres, Ricardo Fraga [Comissão Nacional de Energia Nuclear - CNEN (Brazil); Mesquita, Evandro Tinoco; Mesquita, Cláudio Tinoco [Universidade Federal Fluminense - UFF, Niterói, RJ (Brazil); Hospital Pró-Cardíaco, Rio de Janeiro, RJ (Brazil)

    2014-11-15

    Appropriateness Criteria for nuclear imaging exams were created by American College of Cardiology (ACC) e American Society of Nuclear Cardiology (ASNC) to allow the rational use of tests. Little is known whether these criteria have been followed in clinical practice. To evaluate whether the medical applications of myocardial perfusion scintigraphy (MPS) in a private nuclear medicine service of a tertiary cardiology hospital were suitable to the criteria of indications proposed by the American medical societies in 2005 and 2009 and compare the level of indication of both. We included records of 383 patients that underwent MPS, November 2008 up to February 2009. Demographic characteristics, patient's origin, coronary risk factors, time of medical graduation and appropriateness criteria of medical applications were studied. The criteria were evaluated by two independent physicians and, in doubtful cases, defined by a medical expert in MPS. Mean age was 65 ± 12 years. Of the 367 records reviewed, 236 (64.3%) studies were performed in men and 75 (20.4%) were internee. To ACC 2005, 255 (69.5%) were considered appropriate indication and 13 (3.5%) inappropriate. With ACC 2009, 249 (67.8%) were considered appropriate indications and 13 (5.2%) inappropriate. We observed a high rate of adequacy of medical indications for MPS. Compared to the 2005 version, 2009 did not change the results.

  7. Criteria for Determination of MC and A System Effectiveness

    International Nuclear Information System (INIS)

    Johnson, Geneva; Long, DeAnn; Albright, Ross; Wright, John

    2008-01-01

    The Nevada Test Site (NTS) is a test bed for implementation of the Safeguards First Principles Initiative (SFPI), a risk-based approach to Material Control and Accountability (MC and A) requirements. The Comprehensive Assessment of Safeguards Strategies (COMPASS) model is used to determine the effectiveness of safeguards systems under SFPI. Under this model, MC and A is divided into nine primary elements. Each element is divided into sub-elements. Then, each sub-element is assigned two values, effectiveness and contribution, that are used to calculate the rating. Effectiveness is a measure of sub-element implementation and how well it meets requirements. Contribution is a relative measure of the importance, and functions as a weighting factor. The COMPASS model provides the methodology for calculation of element and subelement, but not the actual criteria. Each site must develop its own criteria. For the rating to be meaningful, the effectiveness criteria must be objective and based on explicit, measurable criteria. Contribution (weights) must reflect the importance within the MC and A program. This paper details the NTS approach to system effectiveness and contribution values, and will cover the following: the basis for the ratings, an explanation of the contribution weights, and the objective, performance-based effectiveness criteria. Finally, the evaluation process will be described

  8. Training review criteria and procedures

    International Nuclear Information System (INIS)

    1986-07-01

    The industry, through commitment to the INPO-managed Training Accreditation Program, is implementing what is referred to as performance-based training, or the Systems Approach to Training (SAT). The NRC considers the following five elements as essential to these training programs: Systematic analysis of the jobs to be performed; learning objectives that are derived from the analysis and that describe desired performance after training; Training design and implementation based on the learning objectives; Evaluation of trainee mastery of the objectives during training; and evaluation and revision of the training based on the performance of trained personnel in the job setting. As indicated in the ''Commission Policy Statement on Training and Qualifications of Nuclear Power Plant Personnel'' of March 20, 1985,''the NRC will continue to closely monitor the process [INPO Accreditation] and its results, and ''It remains the continuing responsibility of the NRC to independently evaluate applicants' and licensees' implementation of improvement programs....'' These procedures provide a systematic means for implementing two of the NRC monitoring functions identified in the Commission Policy Statement: ''Continuing evaluation of industry training and qualification program effectiveness,''; and ''Monitoring plant and industry trends and events involving personnel errors.''

  9. Appendix B : Dichotomy and Criteria

    NARCIS (Netherlands)

    Boucherie, Richard; van Dijk, Nico M.; Boucherie, Richard; van Dijk, Nico

    2017-01-01

    The table below gives a compact overview of the dichotomy on Discrete or continous (time and state) modeling aspects. Here the distinction is made based upon the natural or primary description, i.e. not on the used solution procedure e.g. as by uniformization. It also states the performance measure

  10. Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation.

    Directory of Open Access Journals (Sweden)

    Nicola Gagliani

    Full Text Available BACKGROUND: A large pool of preexisting alloreactive effector T cells can cause allogeneic graft rejection following transplantation. However, it is possible to induce transplant tolerance by altering the balance between effector and regulatory T (Treg cells. Among the various Treg-cell types, Foxp3(+Treg and IL-10-producing T regulatory type 1 (Tr1 cells have frequently been associated with tolerance following transplantation in both mice and humans. Previously, we demonstrated that rapamycin+IL-10 promotes Tr1-cell-associated tolerance in Balb/c mice transplanted with C57BL/6 pancreatic islets. However, this same treatment was unsuccessful in C57BL/6 mice transplanted with Balb/c islets (classified as a stringent transplant model. We accordingly designed a protocol that would be effective in the latter transplant model by simultaneously depleting effector T cells and fostering production of Treg cells. We additionally developed and tested a clinically translatable protocol that used no depleting agent. METHODOLOGY/PRINCIPAL FINDINGS: Diabetic C57BL/6 mice were transplanted with Balb/c pancreatic islets. Recipient mice transiently treated with anti-CD45RB mAb+rapamycin+IL-10 developed antigen-specific tolerance. During treatment, Foxp3(+Treg cells were momentarily enriched in the blood, followed by accumulation in the graft and draining lymph node, whereas CD4(+IL-10(+IL-4(- T (i.e., Tr1 cells localized in the spleen. In long-term tolerant mice, only CD4(+IL-10(+IL-4(- T cells remained enriched in the spleen and IL-10 was key in the maintenance of tolerance. Alternatively, recipient mice were treated with two compounds routinely used in the clinic (namely, rapamycin and G-CSF; this drug combination promoted tolerance associated with CD4(+IL-10(+IL-4(- T cells. CONCLUSIONS/SIGNIFICANCE: The anti-CD45RB mAb+rapamycin+IL-10 combined protocol promotes a state of tolerance that is IL-10 dependent. Moreover, the combination of rapamycin+G-CSF induces

  11. Swiftness movement evaluation criteria in women's rowing

    Directory of Open Access Journals (Sweden)

    Volodymyr Bogush

    2017-08-01

    Full Text Available Purpose: to develop criteria for assessing the speed capabilities of the pace of movement, time and speed of one movement, the frequency of movements that ensure the performance of motor actions in certain conditions of a specific period of time. Material & Methods: the girls, students of the Higher School of Physical Culture and university students, specializing in rowing, various age groups and sports qualification were surveyed, all 73 athletes. According to the method of measuring the effect of the training action developed by us, we studied the speed capabilities that characterize the manifestation of the quality of swiftness. On a special stand athletes made hand movements from the target to target. In the first period of the test, with a duration of 15 seconds, the athletes were to gain maximum speed; In the second period, with a duration of 60 s, it was necessary to maintain the achieved speed – distance velocity was investigated; in the third period – 15 seconds, speed endurance was determined – the athletes were supposed to perform the motor task with the maximum speed. The pace, time and speed of single movement, the frequency of movements were determined, and sensorimotor responses to sound and light stimuli were studied in modeling the conditions of training and competitive activity. Result: formation and improvement of motor abilities in specific age ranges is caused by high rates of development of morphological and functional indicators in sensitive periods. Obtained results characterize the individual psycho-physiological characteristics of the athlete's body in the context of modeling sports activities, show a different reaction in the observed age groups, a different level of sports qualification, which makes it possible to make adjustments in improving the speed abilities and effectively manage the training process. Conclusion: based on a comparative analysis of the studies that carried out, criteria were developed for

  12. Diagnostic criteria for DCD : Past and future

    NARCIS (Netherlands)

    Smits-Engelsman, Bouwien; Schoemaker, Marina; Delabastita, Tijs; Hoskens, Jasmine; Geuze, Reint

    The aim of this review was to gather information on how well authors comply to DSM criteria in their description and selection of children with DCD. We investigated which selection criteria were used in experimental and intervention studies published in the last 5 years (2010-2014). Results on 176

  13. Criteria for Producing CLIL Learning Material

    Science.gov (United States)

    Mehisto, Peeter

    2012-01-01

    This article first describes some general criteria that can be applied to the development of any type of learning materials. Second, the article lists criteria for creating CLIL (content and language integrated learning)-specific learning materials, and provides examples of how to apply each proposed criterion whilst also providing a corresponding…

  14. Criteria for Environmentally Associated Autoimmune Diseases

    Science.gov (United States)

    Pollard, K. Michael; Parks, Christine G.; Germolec, Dori R.; Leung, Patrick S.C.; Selmi, Carlo; Humble, Michael C.; Rose, Noel R.

    2012-01-01

    Increasing evidence supports a role for the environment in the development of autoimmune diseases, as reviewed in the accompanying three papers from the National Institute of Environmental Health Sciences Expert Panel Workshop. An important unresolved issue, however, is the development of criteria for identifying autoimmune disease phenotypes for which the environment plays a causative role, herein referred to as environmentally associated autoimmune diseases. There are several different areas in which such criteria need to be developed, including: 1) identifying the necessary and sufficient data to define environmental risk factors for autoimmune diseases meeting current classification criteria; 2) establishing the existence of and criteria for new environmentally associated autoimmune disorders that do not meet current disease classification criteria; and 3) identifying in clinical practice specific environmental agents that induce autoimmune disease in individual patients. Here we discuss approaches that could be useful for developing criteria in these three areas, as well as factors that should be considered in evaluating the evidence for criteria that can distinguish individuals with such disorders from individuals without such disorders with high sensitivity and specificity. Current studies suggest that multiple lines of complementary evidence will be important and that in many cases there will be clinical, serologic, genetic, epigenetic, and/or other laboratory features that could be incorporated as criteria for environmentally associated autoimmune diseases to improve diagnosis and treatment and possibly allow for preventative strategies in the future. PMID:22771005

  15. Aspirational Model Teaching Criteria for Psychology

    Science.gov (United States)

    Richmond, Aaron S.; Boysen, Guy A.; Gurung, Regan A. R.; Tazeau, Yvette N.; Meyers, Steven A.; Sciutto, Mark J.

    2014-01-01

    In 2011, the Society for the Teaching of Psychology commissioned a presidential task force to document teaching criteria for model psychology teachers in undergraduate education. The resulting list of criteria reflects activities related to face-to-face course interaction and online teaching, training, and education; course design; implementation…

  16. 42 CFR 456.5 - Evaluation criteria.

    Science.gov (United States)

    2010-10-01

    ...) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL General Provisions § 456.5 Evaluation criteria. The agency must establish and use written criteria for evaluating the appropriateness and quality of Medicaid services. This section does not apply to services in hospitals and mental hospitals. For these facilities...

  17. 34 CFR 104.13 - Employment criteria.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Employment criteria. 104.13 Section 104.13 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION... Employment Practices § 104.13 Employment criteria. (a) A recipient may not make use of any employment test or...

  18. Who and Racist criteria on CT

    International Nuclear Information System (INIS)

    Servente, L.

    2012-01-01

    This presentation is about Who and Recist criteria on CT.These are rules to the evaluation of the solid tumors treatment response as well as different concepts of measurability criteria of blastic changes, target /non target lesions, adenopathies, lytic, cystic , non-measurable disease and progressive lesions

  19. 16 CFR 1301.5 - Banning criteria.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Banning criteria. 1301.5 Section 1301.5 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS BAN OF UNSTABLE REFUSE BINS § 1301.5 Banning criteria. (a) Any refuse bin of metal construction produced or...

  20. Revised diagnostic criteria for the Marfan syndrome

    NARCIS (Netherlands)

    de Paepe, A.; Devereux, R. B.; Dietz, H. C.; Hennekam, R. C.; Pyeritz, R. E.

    1996-01-01

    In 1986, the diagnosis of the Marfan syndrome was codified on the basis of clinical criteria in the Berlin nosology [Beighton et al., 1988]. Over time, weaknesses have emerged in these criteria, a problem accentuated by the advent of molecular testing. In this paper, we propose a revision of

  1. Hanford Site liquid waste acceptance criteria

    International Nuclear Information System (INIS)

    LUECK, K.J.

    1999-01-01

    This document provides the waste acceptance criteria for liquid waste managed by Waste Management Federal Services of Hanford, Inc. (WMH). These waste acceptance criteria address the various requirements to operate a facility in compliance with applicable environmental, safety, and operational requirements. This document also addresses the sitewide miscellaneous streams program

  2. [Primary childhood vasculitis new classification criteria

    DEFF Research Database (Denmark)

    Herlin, T.; Nielsen, Susan

    2008-01-01

    Primary vasculitis is seen in both adults and children, but some of the diseases like Kawasaki disease occur primarily in children. The Chapel Hill Classification Criteria for primary vasculitis refers to the size of vessels but has not been validated in children. Recently, new criteria...

  3. Deterministic algorithms for multi-criteria TSP

    NARCIS (Netherlands)

    Manthey, Bodo; Ogihara, Mitsunori; Tarui, Jun

    2011-01-01

    We present deterministic approximation algorithms for the multi-criteria traveling salesman problem (TSP). Our algorithms are faster and simpler than the existing randomized algorithms. First, we devise algorithms for the symmetric and asymmetric multi-criteria Max-TSP that achieve ratios of

  4. Learners' Epistemic Criteria for Good Scientific Models

    Science.gov (United States)

    Pluta, William J.; Chinn, Clark A.; Duncan, Ravit Golan

    2011-01-01

    Epistemic criteria are the standards used to evaluate scientific products (e.g., models, evidence, arguments). In this study, we analyzed epistemic criteria for good models generated by 324 middle-school students. After evaluating a range of scientific models, but before extensive instruction or experience with model-based reasoning practices,…

  5. 29 CFR 1904.4 - Recording criteria.

    Science.gov (United States)

    2010-07-01

    ... criteria. (Needlestick and sharps injury cases, tuberculosis cases, hearing loss cases, medical removal... Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR RECORDING AND REPORTING OCCUPATIONAL INJURIES AND ILLNESSES Recordkeeping Forms and Recording Criteria § 1904.4...

  6. Revised response criteria for malignant lymphoma

    DEFF Research Database (Denmark)

    Cheson, Bruce D; Pfistner, Beate; Juweid, Malik E

    2007-01-01

    PURPOSE: Standardized response criteria are needed to interpret and compare clinical trials and for approval of new therapeutic agents by regulatory agencies. METHODS: The International Working Group response criteria (Cheson et al, J Clin Oncol 17:1244, 1999) were widely adopted, but required re...

  7. Revised response criteria for malignant lymphoma

    NARCIS (Netherlands)

    Cheson, Bruce D.; Pfistner, Beate; Juweid, Malik E.; Gascoyne, Randy D.; Specht, Lena; Horning, Sandra J.; Coiffier, Bertrand; Fisher, Richard I.; Hagenbeek, Anton; Zucca, Emanuele; Rosen, Steven T.; Stroobants, Sigrid; Lister, T. Andrew; Hoppe, Richard T.; Dreyling, Martin; Tobinai, Kensei; Vose, Julie M.; Connors, Joseph M.; Federico, Massimo; Diehl, Volker

    2007-01-01

    PURPOSE: Standardized response criteria are needed to interpret and compare clinical trials and for approval of new therapeutic agents by regulatory agencies. METHODS: The International Working Group response criteria (Cheson et al, J Clin Oncol 17:1244, 1999) were widely adopted, but required

  8. Criteria for Selecting Document Delivery Suppliers.

    Science.gov (United States)

    Machovec, George S.

    1994-01-01

    Presents selection criteria for libraries choosing document delivery suppliers as an alternative to traditional interlibrary loan. Categories of commercial services are described, and selection criteria including ease of use, ordering options, charging and billing, copyright issues, enduser access, turnaround time, telecommunications options,…

  9. Proposed diagnostic criteria for internet addiction.

    Science.gov (United States)

    Tao, Ran; Huang, Xiuqin; Wang, Jinan; Zhang, Huimin; Zhang, Ying; Li, Mengchen

    2010-03-01

    The objective of this study was to develop diagnostic criteria for internet addiction disorder (IAD) and to evaluate the validity of our proposed diagnostic criteria for discriminating non-dependent from dependent internet use in the general population. This study was conducted in three stages: the developmental stage (110 subjects in the survey group; 408 subjects in the training group), where items of the proposed diagnostic criteria were developed and tested; the validation stage (n = 405), where the proposed criteria were evaluated for criterion-related validity; and the clinical stage (n = 150), where the criteria and the global clinical impression of IAD were evaluated by more than one psychiatrist to determine inter-rater reliability. The proposed internet addiction diagnostic criteria consisted of symptom criterion (seven clinical symptoms of IAD), clinically significant impairment criterion (functional and psychosocial impairments), course criterion (duration of addiction lasting at least 3 months, with at least 6 hours of non-essential internet usage per day) and exclusion criterion (exclusion of dependency attributed to psychotic disorders). A diagnostic score of 2 + 1, where the first two symptoms (preoccupation and withdrawal symptoms) and at least one of the five other symptoms (tolerance, lack of control, continued excessive use despite knowledge of negative effects/affects, loss of interests excluding internet, and use of the internet to escape or relieve a dysphoric mood) was established. Inter-rater reliability was 98%. Our findings suggest that the proposed diagnostic criteria may be useful for the standardization of diagnostic criteria for IAD.

  10. 2012 provisional classification criteria for polymyalgia rheumatica

    DEFF Research Database (Denmark)

    Dasgupta, Bhaskar; Cimmino, Marco A; Maradit-Kremers, Hilal

    2012-01-01

    The objective of this study was to develop EULAR/ACR classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring al...

  11. Hybrid multiple criteria decision-making methods

    DEFF Research Database (Denmark)

    Zavadskas, Edmundas Kazimieras; Govindan, K.; Antucheviciene, Jurgita

    2016-01-01

    Formal decision-making methods can be used to help improve the overall sustainability of industries and organisations. Recently, there has been a great proliferation of works aggregating sustainability criteria by using diverse multiple criteria decision-making (MCDM) techniques. A number of revi...

  12. Various criteria in the evaluation of biomedical named entity recognition

    Directory of Open Access Journals (Sweden)

    Lin Yu-Chun

    2006-02-01

    Full Text Available Abstract Background Text mining in the biomedical domain is receiving increasing attention. A key component of this process is named entity recognition (NER. Generally speaking, two annotated corpora, GENIA and GENETAG, are most frequently used for training and testing biomedical named entity recognition (Bio-NER systems. JNLPBA and BioCreAtIvE are two major Bio-NER tasks using these corpora. Both tasks take different approaches to corpus annotation and use different matching criteria to evaluate system performance. This paper details these differences and describes alternative criteria. We then examine the impact of different criteria and annotation schemes on system performance by retesting systems participated in the above two tasks. Results To analyze the difference between JNLPBA's and BioCreAtIvE's evaluation, we conduct Experiment 1 to evaluate the top four JNLPBA systems using BioCreAtIvE's classification scheme. We then compare them with the top four BioCreAtIvE systems. Among them, three systems participated in both tasks, and each has an F-score lower on JNLPBA than on BioCreAtIvE. In Experiment 2, we apply hypothesis testing and correlation coefficient to find alternatives to BioCreAtIvE's evaluation scheme. It shows that right-match and left-match criteria have no significant difference with BioCreAtIvE. In Experiment 3, we propose a customized relaxed-match criterion that uses right match and merges JNLPBA's five NE classes into two, which achieves an F-score of 81.5%. In Experiment 4, we evaluate a range of five matching criteria from loose to strict on the top JNLPBA system and examine the percentage of false negatives. Our experiment gives the relative change in precision, recall and F-score as matching criteria are relaxed. Conclusion In many applications, biomedical NEs could have several acceptable tags, which might just differ in their left or right boundaries. However, most corpora annotate only one of them. In our

  13. An objective approach to determining criteria weights

    Directory of Open Access Journals (Sweden)

    Milić R. Milićević

    2012-01-01

    Full Text Available This paper presents an objective approach to determining criteria weights that can be successfully used in multiple criteria models. The methods of entropy, CRITIC and FANMA are presented in this paper as well as a possible combination of the methods of objective and subjective approaches. Although based on different theoretical settings, and therefore with different algorithms of realization, all methods have a decision matrix as a starting point. An objective approach to determining the weight of criteria eliminates the negative impacts of a decision maker on criteria weights as well as on the final solution of multicriteria problems. The main aim of this paper is to systematize description procedures as a kind of help when encountering a problem of determining the criteria weights for solving multicriteria tasks. A possibility of the method application is shown in a numerical example.

  14. [Work capacity--approach and evaluation criteria].

    Science.gov (United States)

    Sarić, Marko; Sarić, Biserka

    2002-12-01

    In occupations involving specific risk factors, the employer is required by law to have his candidates/employees physically examined in the course of pre-placement/work, as a measure of health and safety protection. Upon examination, the occupational health physician issues to the employer a statement of the candidate's/employee's suitability for work. Mandatory pre-placement and periodic medical examinations are also required for workers who may affect the health and safety of the public such as workers in public transportation or food processing. This paper looks into the implementation of regulations and actual practice in performing relevant medical examinations. One of the issues described is the determination of a worker's temporary disability. Practicing physician determines a disability and rates the physical impairment. She or he has to translate clinical information into a decision about whether a patient is able to work. This decision is the basis for healthcare compensation and benefits and requires knowledge not only of the illness or injury and the patient, but also of the job tasks and exposure. From the medical standpoint, it may be difficult to determine when a period of temporary disability has ended or if a degree of impairment has remained, and when the temporary partial or total disability has become permanent. The paper discusses the assessment of total or partial permanent disabilities based on the new Pension Insurance Act (1998) and the differences from earlier criteria, summarising the implementation of new regulations for years 2000 and 2001.

  15. Criteria for achieving actinide reduction goals

    International Nuclear Information System (INIS)

    Liljenzin, J.O.

    1996-01-01

    In order to discuss various criteria for achieving actinide reduction goals, the goals for actinide reduction must be defined themselves. In this context the term actinides is interpreted to mean plutonium and the so called ''minor actinides'' neptunium, americium and curium, but also protactinium. Some possible goals and the reasons behind these will be presented. On the basis of the suggested goals it is possible to analyze various types of devices for production of nuclear energy from uranium or thorium, such as thermal or fast reactors and accelerator driven system, with their associated fuel cycles with regard to their ability to reach the actinide reduction goals. The relation between necessary single cycle burn-up values, fuel cycle processing losses and losses to waste will be defined and discussed. Finally, an attempt is made to arrange the possible systems on order of performance with regard to their potential to reduce the actinide inventory and the actinide losses to wastes. (author). 3 refs, 3 figs, 2 tabs

  16. Computational compliance criteria in water hammer modelling

    Science.gov (United States)

    Urbanowicz, Kamil

    2017-10-01

    Among many numerical methods (finite: difference, element, volume etc.) used to solve the system of partial differential equations describing unsteady pipe flow, the method of characteristics (MOC) is most appreciated. With its help, it is possible to examine the effect of numerical discretisation carried over the pipe length. It was noticed, based on the tests performed in this study, that convergence of the calculation results occurred on a rectangular grid with the division of each pipe of the analysed system into at least 10 elements. Therefore, it is advisable to introduce computational compliance criteria (CCC), which will be responsible for optimal discretisation of the examined system. The results of this study, based on the assumption of various values of the Courant-Friedrichs-Levy (CFL) number, indicate also that the CFL number should be equal to one for optimum computational results. Application of the CCC criterion to own written and commercial computer programmes based on the method of characteristics will guarantee fast simulations and the necessary computational coherence.

  17. Common QA/QM Criteria for Multinational Vendor Inspection

    International Nuclear Information System (INIS)

    2014-01-01

    This VICWG document provides the 'Common QA/QM Criteria' which will be used in Multinational Vendor Inspection. The 'Common QA/QM Criteria' provides the basic consideration when performing the Vendor Inspection. These criteria has been developed in conformity with International Codes and Standards such as IAEA, ISO and so on that MDEP member countries adopted. The purpose of the VICWG is to establish areas of co-operation in the Vendor Inspection practices among MDEP member countries as described in the MDEP issue-specific Terms of Reference (ToR). As part of this, from the beginning, a survey was performed to understand and to identify areas of commonality and differences between regulatory practices of member countries in the area of vendor inspection. The VICWG also collaborated by performing Witnessed Inspections and Joint Inspections. Through these activities, it was recognized that member countries commonly apply the IAEA safety standard (GS-R-3) to the vendor inspection criteria, and almost ail European member countries apply the ISO standard (ISO9001). In the US, the NRC regulatory requirement in 10 CFR, Part 50, Appendix B is used. South Korea uses the same criteria as in the US. As a result of the information obtained, a comparison table between codes and standards (IAEAGS-R-3, ISO 9001:2008.10CFR50 Appendix Band ASME NQA-1) has been developed in order to inform the development of 'Common QA/QM Criteria'. The result is documented in Table 1, 'MDEP CORE QA/QM Requirement and Comparison between Codes and Standards'. In addition, each country's criteria were compared with the US 10CFR50 Appendix B as a template. Table 2 shows VICWG Survey on Quality Assurance Program Requirements. Through these activities above, we considered that the core requirements should be consistent with both IAEA safety standard and ISO standard, and considered that the common requirements in the US 10CFR50 Appendix B used to the survey

  18. 78 FR 38091 - Airworthiness Criteria: Proposed Airship Design Criteria for Lockheed Martin Aeronautics Model...

    Science.gov (United States)

    2013-06-25

    ...] Airworthiness Criteria: Proposed Airship Design Criteria for Lockheed Martin Aeronautics Model LMZ1M Airship... on the proposed design criteria for the Lockheed Martin Aeronautics model LMZ1M airship. On March 12, 2012 Lockheed Martin Aeronautics submitted an application for type certification for the model LMZ1M...

  19. 40 CFR 63.91 - Criteria for straight delegation and criteria common to all approval options.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Criteria for straight delegation and... Criteria for straight delegation and criteria common to all approval options. (a) Applicable approval... following paragraphs. (1) Unchanged Federal section 112 rules (“straight delegation”). To obtain approval of...

  20. Selection criteria for scoring amplified fragment length polymorphisms (AFLPs) positively affect the reliability of population genetic parameter estimates.

    Science.gov (United States)

    Herrmann, Doris; Poncet, Bénédicte N; Manel, Stéphanie; Rioux, Delphine; Gielly, Ludovic; Taberlet, Pierre; Gugerli, Felix

    2010-04-01

    A reliable data set is a fundamental prerequisite for consistent results and conclusions in population genetic studies. However, marker scoring of genetic fingerprints such as amplified fragment length polymorphisms (AFLPs) is a highly subjective procedure, inducing inconsistencies owing to personal or laboratory-specific criteria. We applied two alternative marker selection algorithms, the newly developed script scanAFLP and the recently published AFLPScore, to a large AFLP genome scan to test how population genetic parameters and error rates were affected. These results were confronted with replicated random selections of marker subsets. We show that the newly developed marker selection criteria reduced the mismatch error rate and had a notable influence on estimates of genetic diversity and differentiation. Both effects are likely to influence biological inference. For example, genetic diversity (HS) was 29% lower while genetic differentiation (FST) was 8% higher when applying scanAFLP compared with AFLPScore. Likewise, random selections of markers resulted in substantial deviations of population genetic parameters compared with the data sets including specific selection criteria. These randomly selected marker sets showed surprisingly low variance among replicates. We conclude that stringent marker selection and phenotype calling reduces noise in the data set while retaining patterns of population genetic structure.

  1. Overall Equipment Effectiveness Implementation Criteria

    Science.gov (United States)

    Abramova, I. G.; Abramov, D. A.

    2018-01-01

    This article documents the methods applied in production control technics specifically focused on commonly used parameter OEE (Overall Equipment Effectiveness). The indicators of extensive and intensive use of equipment are considered. Their appointment this is comparison in the same type of production within the industry and comparison of single-type and / or different types of equipment in terms of capacity. However, it is shown that there is no possibility of revealing the reasons for the machine’s operation: productive / unproductive, with disturbances. Therefore, in the article reveals the approaches to calculating the indicator characterizing the direct operation of the equipment. The Machine Load coefficient is approaching closely to the indicator of the efficiency of the use of equipment. Methods analysis is proceeded through the historically applied techniques such as “Stopwatch” and “Motion” studies. Was performed the analysis of the efficiency index of OEE equipment using the comparable indexes performance of equipment in the Russian practice. An important indicator of OEE contains three components. The meaning of each of them reflects historically applicable indicators. The value of the availability of equipment indicator is close to the value of the equipment extensibility index. The value of the indicator of the efficiency of work can be compared with the characteristic of the capacity of the equipment and the indicator of the quality level can meet the requirements for compliance with the manufacturing technology. Shown that the sum of the values of the coefficient of “Availability” of the equipment and the value of the “Factor of compaction of working hours” are one. As well as the total value of the indicator “level of quality” and the coefficient of marriage given in the result unit. The measurability of the indicators makes it possible to make a prediction about efficiency of the equipment.

  2. Validity of helicopter emergency medical services dispatch criteria for traumatic injuries: A systematic review

    NARCIS (Netherlands)

    A.N. Ringburg (Akkie); G. de Ronde (Gijs); S. Thomas (Siep); E.M.M. van Lieshout (Esther); P. Patka (Peter); I.B. Schipper (Inger)

    2009-01-01

    textabstractObjective. This review provides an overview of the validity of Helicopter Emergency Medical Services (HEMS) dispatch criteria for severely injured patients. Methods. A systematic literature search was performed. English written and peer-reviewed publications on HEMS dispatch criteria

  3. Dynamic criteria for partitioning and transmutation

    International Nuclear Information System (INIS)

    Lu, A.H.

    1991-11-01

    This paper addresses dynamic criteria intended to optimize partitioning and transmutation (P-T) concept development supporting improved nuclear waste management. Six criteria are proposed initially and the rationale for each is briefly explained. Each criterion is used as a measure (or dimension) on which the developed concepts can be evaluated. The criteria allow the P-T concepts to be evaluated in an integral system including long-term energy needs, fuel cycle, and waste management. New criteria will be identified along with the P-T concept development, and each criterion will be realistically weighted so that it is comparable in an overall criteria evaluation. The weights are subject to change as a result of technical advancements and public perception on various issues. Incomplete criteria will result in a poor choice because important factors may not be considered when the decision is made. A successful decision on the optimal P-T system depends on the completeness of criteria (dimensions) as well as realistic weights assigned to each criterion

  4. Materials Selection Criteria for Nuclear Power Applications: A Decision Algorithm

    Science.gov (United States)

    Rodríguez-Prieto, Álvaro; Camacho, Ana María; Sebastián, Miguel Ángel

    2016-02-01

    An innovative methodology based on stringency levels is proposed in this paper and improves the current selection method for structural materials used in demanding industrial applications. This paper describes a new approach for quantifying the stringency of materials requirements based on a novel deterministic algorithm to prevent potential failures. We have applied the new methodology to different standardized specifications used in pressure vessels design, such as SA-533 Grade B Cl.1, SA-508 Cl.3 (issued by the American Society of Mechanical Engineers), DIN 20MnMoNi55 (issued by the German Institute of Standardization) and 16MND5 (issued by the French Nuclear Commission) specifications and determine the influence of design code selection. This study is based on key scientific publications on the influence of chemical composition on the mechanical behavior of materials, which were not considered when the technological requirements were established in the aforementioned specifications. For this purpose, a new method to quantify the efficacy of each standard has been developed using a deterministic algorithm. The process of assigning relative weights was performed by consulting a panel of experts in materials selection for reactor pressure vessels to provide a more objective methodology; thus, the resulting mathematical calculations for quantitative analysis are greatly simplified. The final results show that steel DIN 20MnMoNi55 is the best material option. Additionally, more recently developed materials such as DIN 20MnMoNi55, 16MND5 and SA-508 Cl.3 exhibit mechanical requirements more stringent than SA-533 Grade B Cl.1. The methodology presented in this paper can be used as a decision tool in selection of materials for a wide range of applications.

  5. A look at computer system selection criteria

    Science.gov (United States)

    Poole, E. W.; Flowers, F. L.; Stanley, W. I. (Principal Investigator)

    1979-01-01

    There is no difficulty in identifying the criteria involved in the computer selection process; complexity arises in objectively evaluating various candidate configurations against the criteria, based on the user's specific needs. A model for formalizing the selection process consists of two major steps: verifying that the candidate configuration is adequate to the user's programming requirements, and determining an overall system evaluation rating based on cost, usability, adaptability, and availability. A 36 step instruction for computer sizing evaluation is included in the appendix along with a sample application of the configuration adequacy model. Selection criteria and the weighting process are also discussed.

  6. Simplified Stability Criteria for Delayed Neutral Systems

    Directory of Open Access Journals (Sweden)

    Xinghua Zhang

    2014-01-01

    Full Text Available For a class of linear time-invariant neutral systems with neutral and discrete constant delays, several existing asymptotic stability criteria in the form of linear matrix inequalities (LMIs are simplified by using matrix analysis techniques. Compared with the original stability criteria, the simplified ones include fewer LMI variables, which can obviously reduce computational complexity. Simultaneously, it is theoretically shown that the simplified stability criteria and original ones are equivalent; that is, they have the same conservativeness. Finally, a numerical example is employed to verify the theoretic results investigated in this paper.

  7. Operational Criteria Evaluation for Collaboration of Innovative SMEs

    OpenAIRE

    Duzdar, Irem; Kayakutlu, Gülgün; Sennaroğlu, Bahar

    2015-01-01

    SMEs should organize alliances with universities or other research organizations, global business companies, and other SMEs. Each type of alliance has specific risk and success criteria to be studied. SMEs need to construct successful alliances in order to have sustainable business in a competitive environment. Pre-analysis of the path for successful alliances will lead to improvements in innovative power. This study attempts to perform qualitative analysis of the SME alliances in order to ex...

  8. Hydraulic Design Criteria for Spacer Grids of Nuclear Fuel Element

    International Nuclear Information System (INIS)

    Juanico, Luis; Brasnarof, Daniel

    2000-01-01

    In this paper a hydraulic model for calculating the pressure drop on the CARA spacer grids is extended.This model is validated and feedback from experimental hydraulic test performed in a low pressure loop.The importance of the spacer grid geometric parameter (that is, its thickness and length, the number and kind of their fix spacer), developing hydraulic design criteria for spacer grid on fuel element

  9. ECONOMIC UPDATE MECHANISM FIXED ASSETS. CRITERIA FOR ITS EFFECTIVENESS

    OpenAIRE

    Заржевский, П.В.

    2016-01-01

    The article describes the structure of the mechanism of renewal of fixed assets. The main structural elements: 1. The definition of the necessary requirements; 2. Formation of the order as part of the investment strategy; 3. Selection of sources of funding. The notion of an effective mechanism for renewal of fixed assets. Results and performance criteria described mechanism of renewal of fixed assets. The effect of accelerated depreciation on improving the efficiency of the mechanism of renew...

  10. Guidelines for Effective and Defensible Performance Appraisal Systems.

    Science.gov (United States)

    Wells, Ronald G.

    1982-01-01

    Areas to consider when conducting personnel performance evaluations are discussed. They include: job related criteria, subjective criteria, performance expectations, performance standards, regular scheduling of evaluations, and formal documentation. Guidelines to deal with problems in these areas are also presented. (CT)

  11. Validation of proposed diagnostic criteria (the "Budapest Criteria") for Complex Regional Pain Syndrome.

    Science.gov (United States)

    Harden, R Norman; Bruehl, Stephen; Perez, Roberto S G M; Birklein, Frank; Marinus, Johan; Maihofner, Christian; Lubenow, Timothy; Buvanendran, Asokumar; Mackey, Sean; Graciosa, Joseph; Mogilevski, Mila; Ramsden, Christopher; Chont, Melissa; Vatine, Jean-Jacques

    2010-08-01

    Current IASP diagnostic criteria for CRPS have low specificity, potentially leading to overdiagnosis. This validation study compared current IASP diagnostic criteria for CRPS to proposed new diagnostic criteria (the "Budapest Criteria") regarding diagnostic accuracy. Structured evaluations of CRPS-related signs and symptoms were conducted in 113 CRPS-I and 47 non-CRPS neuropathic pain patients. Discriminating between diagnostic groups based on presence of signs or symptoms meeting IASP criteria showed high diagnostic sensitivity (1.00), but poor specificity (0.41), replicating prior work. In comparison, the Budapest clinical criteria retained the exceptional sensitivity of the IASP criteria (0.99), but greatly improved upon the specificity (0.68). As designed, the Budapest research criteria resulted in the highest specificity (0.79), again replicating prior work. Analyses indicated that inclusion of four distinct CRPS components in the Budapest Criteria contributed to enhanced specificity. Overall, results corroborate the validity of the Budapest Criteria and suggest they improve upon existing IASP diagnostic criteria for CRPS. Copyright (c) 2010 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

  12. Fuel safety criteria technical review - Results of OECD/CSNI/PWG2 Task Force on Fuel Safety Criteria

    International Nuclear Information System (INIS)

    Hollasky, N.; Valtonen, K.; Hache, G.; Gross, H.; Bakker, K.; Recio, M.; Bart, G.; Zimmermann, M.; Van Doesburg, W.; Killeen, J.; Meyer, R.O.; Speis, T.

    2000-01-01

    With the advent of advanced fuel and core designs, the adoption of more aggressive operational modes and the implementation of more accurate (best estimate or statistical) design and analysis methods, there is a concern if safety margins have remained adequate. Most - if not all - of the currently existing safety criteria were established during the 60's and early 70's, and verified against experiments with fuel that was available at that time, mostly with unirradiated specimens. Verification was of course performed as designs progressed in later years, however mostly with the aim to be able to prove that these designs adequately complied with existing criteria, and not to establish new limits. The OECD/CSNI/PWG2 Task Force on Fuel Safety Criteria (TFFSC) was therefore given the mandate to technically review the existing fuel safety criteria, focusing on the 'new design' elements (new fuel and core design, cladding materials, manufacturing processes, high burnup, MOX, etc.) introduced by the industry. It should also identify if additional efforts may be required (experimental, analytical) to ensure that the basis for fuel safety criteria is adequate to address the relevant safety issues. In this report, fuel-related criteria are discussed without attempting to categorize them according to event type or risk significance. For each of these 20 criteria, we present a brief description of the criterion as it is used in several applications along with the rationale for having such a criterion. New design elements, such as different cladding materials, higher burnup, and the use of MOX fuels, can affect fuel-related margins and, in some cases, the criteria themselves. Some of the more important effects are mentioned in order to indicate whether the criteria need to be re-evaluated. The discussion may not cover all possible effects, but should be sufficient to identify those criteria that need to be addressed. A summary of these discussions is given in Section 7. As part

  13. Assessment of five different guideline indication criteria for spirometry, including modified GOLD criteria, in order to detect COPD: data from 5,315 subjects in the PLATINO study.

    Science.gov (United States)

    Luize, Ana P; Menezes, Ana Maria B; Perez-Padilla, Rogelio; Muiño, Adriana; López, Maria Victorina; Valdivia, Gonzalo; Lisboa, Carmem; Montes de Oca, Maria; Tálamo, Carlos; Celli, Bartolomé; Nascimento, Oliver A; Gazzotti, Mariana R; Jardim, José R

    2014-10-30

    Spirometry is the gold standard for diagnosing chronic obstructive pulmonary disease (COPD). Although there are a number of different guideline criteria for deciding who should be selected for spirometric screening, to date it is not known which criteria are the best based on sensitivity and specificity. Firstly, to evaluate the proportion of subjects in the PLATINO Study that would be recommended for spirometry testing according to Global initiative for Obstructive Lung Disease (GOLD)-modified, American College of Chest Physicians (ACCP), National Lung Health Education Program (NLHEP), GOLD and American Thoracic Society/European Respiratory Society (ATS/ERS) criteria. Secondly, we aimed to compare the sensitivity, specificity, and positive predictive and negative predictive values, of these five different criteria. Data from the PLATINO study included information on respiratory symptoms, smoking and previous spirometry testing. The GOLD-modified spirometry indication criteria are based on three positive answers out of five questions: the presence of cough, phlegm in the morning, dyspnoea, age over 40 years and smoking status. Data from 5,315 subjects were reviewed. Fewer people had an indication for spirometry (41.3%) according to the GOLD-modified criteria, and more people had an indication for spirometry (80.4%) by the GOLD and ATS/ERS criteria. A low percentage had previously had spirometry performed: GOLD-modified (14.5%); ACCP (13.2%); NLHEP (12.6%); and GOLD and ATS/ERS (12.3%). The GOLD-modified criteria showed the least sensitivity (54.9) and the highest specificity (61.0) for detecting COPD, whereas GOLD and ATS/ERS criteria showed the highest sensitivity (87.9) and the least specificity (20.8). There is a considerable difference in the indication for spirometry according to the five different guideline criteria. The GOLD-modified criteria recruit less people with the greatest sum of sensitivity and specificity.

  14. Waste acceptance criteria for the Waste Isolation Pilot Plant

    International Nuclear Information System (INIS)

    1996-04-01

    The Waste Isolation Pilot Plant (WIPP) Waste Acceptance Criteria (WAC), DOE/WIPP-069, was initially developed by a U.S. Department of Energy (DOE) Steering Committee to provide performance requirements to ensure public health and safety as well as the safe handling of transuranic (TRU) waste at the WIPP. This revision updates the criteria and requirements of previous revisions and deletes those which were applicable only to the test phase. The criteria and requirements in this document must be met by participating DOE TRU Waste Generator/Storage Sites (Sites) prior to shipping contact-handled (CH) and remote-handled (RH) TRU waste forms to the WIPP. The WIPP Project will comply with applicable federal and state regulations and requirements, including those in Titles 10, 40, and 49 of the Code of Federal Regulations (CFR). The WAC, DOE/WIPP-069, serves as the primary directive for assuring the safe handling, transportation, and disposal of TRU wastes in the WIPP and for the certification of these wastes. The WAC identifies strict requirements that must be met by participating Sites before these TRU wastes may be shipped for disposal in the WIPP facility. These criteria and requirements will be reviewed and revised as appropriate, based on new technical or regulatory requirements. The WAC is a controlled document. Revised/changed pages will be supplied to all holders of controlled copies

  15. Early Site Permit Demonstration Program: Regulatory criteria evaluation report

    International Nuclear Information System (INIS)

    1993-03-01

    The primary objective of the Early Site Plan Demonstration Program (ESPDP) is to demonstrate successfully the use of 10CFR52 to obtain ESPs for one or more US sites for one (or more) ALWR nuclear power plants. It is anticipated that preparation of the ESP application and interaction with NRC during the application review process will result not only in an ESP for the applicant(s) but also in the development of criteria and definition of processes, setting the precedent that facilitates ESPs for subsequent ESP applications. Because siting regulatory processes and acceptance criteria are contained in over 100 separate documents, comprehensive licensing and technical reviews were performed to establish whether the requirements and documentation are self-consistent, whether the acceptance criteria are sufficiently well-defined and clear, and whether the licensing process leading to the issuance of an ESP is unambiguously specified. This document provides appendices A and B of this report. Appendix A contains a list of regulations, regulatory guidance, and acceptance criteria; Appendix B contains a cross-reference index of siting-related documentation

  16. Establishing seismic design criteria to achieve an acceptable seismic margin

    International Nuclear Information System (INIS)

    Kennedy, R.P.

    1997-01-01

    In order to develop a risk based seismic design criteria the following four issues must be addressed: (1) What target annual probability of seismic induced unacceptable performance is acceptable? (2). What minimum seismic margin is acceptable? (3) Given the decisions made under Issues 1 and 2, at what annual frequency of exceedance should the Safe Shutdown Earthquake ground motion be defined? (4) What seismic design criteria should be established to reasonably achieve the seismic margin defined under Issue 2? The first issue is purely a policy decision and is not addressed in this paper. Each of the other three issues are addressed. Issues 2 and 3 are integrally tied together so that a very large number of possible combinations of responses to these two issues can be used to achieve the target goal defined under Issue 1. Section 2 lays out a combined approach to these two issues and presents three potentially attractive combined resolutions of these two issues which reasonably achieves the target goal. The remainder of the paper discusses an approach which can be used to develop seismic design criteria aimed at achieving the desired seismic margin defined in resolution of Issue 2. Suggestions for revising existing seismic design criteria to more consistently achieve the desired seismic margin are presented

  17. National Recommended Water Quality Criteria - Organoleptic Effects

    Science.gov (United States)

    These criteria are based on organoleptic (taste and odor) effects. Because of variations in chemical nomenclature systems, this listing of pollutants does not duplicate the listing in Appendix A of 40 CFR Part 423.

  18. application of decision theory based criteria

    African Journals Online (AJOL)

    2012-11-03

    Nov 3, 2012 ... APPLICATION OF DECISION THEORY BASED CRITERIA FOR. STRUCTURAL APPRAISAL OF A BUILDING DURING. CONSTRUCTION. C. Nwaobakata, S. Sulea. Department of Civil and Environmental Engineering, University of Port Harcourt, Rivers State, Nigeria. Email: asamvictoryahead@yahoo.com.

  19. Ebook Evaluation Criteria: A Proposed Checklist

    Directory of Open Access Journals (Sweden)

    Amir Ghaebi

    2010-09-01

    Full Text Available E-books embody diverse features, each of which could contribute towards increasing their user-agreeability and attracting more users. In order to select an Ebook best suited to their needs, both users and librarians consider a set of criteria. The present study aims at providing the evaluation criteria from the standpoint of both the users and librarys by employing two approaches, i.e. through considering the characteristics of the electronic environment, and also maintaining the desired features of the printed media in E-books. By reviewing the resources published in the field of E-books, 15 criteria along with 101 components have been collectively discussed for evaluation of the suitable E-book for users and libraries. Four criteria with 24 components have been solely devised for libraries and librarians.

  20. Criteria for Comparing Children's Web Search Tools.

    Science.gov (United States)

    Kuntz, Jerry

    1999-01-01

    Presents criteria for evaluating and comparing Web search tools designed for children. Highlights include database size; accountability; categorization; search access methods; help files; spell check; URL searching; links to alternative search services; advertising; privacy policy; and layout and design. (LRW)

  1. Proposed changes in intermediate pipe break criteria

    International Nuclear Information System (INIS)

    Schmitz, R.P.

    1984-01-01

    Bechtel Power Corporation proposed to the US NRC in 1983 that the NRC eliminate from their criteria all intermediate breaks. Bechtel's rationale for the proposal and support for their position are presented

  2. Infill sampling criteria to locate extremes

    CSIR Research Space (South Africa)

    Watson, AG

    1995-07-01

    Full Text Available Three problem-dependent meanings for engineering ''extremes'' are motivated, established, and translated into formal geostatistical (model-based) criteria for designing infill sample networks. (I) Locate an area within the domain of interest where a...

  3. The DSM diagnostic criteria for pedophilia.

    Science.gov (United States)

    Blanchard, Ray

    2010-04-01

    This paper contains the author's report on pedophilia, submitted on June 2, 2008, to the work group charged with revising the diagnoses concerning sexual and gender identity disorders for the fifth edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM). The author reviews the previously published criticisms and empirical research concerning the diagnostic criteria for pedophilia and presents criticism and relevant research of his own. The review shows that the DSM diagnostic criteria for pedophilia have repeatedly been criticized as unsatisfactory on logical or conceptual grounds, and that published empirical studies on the reliability and validity of these criteria have produced ambiguous results. It therefore seems that the current (i.e., DSM-IV-TR) diagnostic criteria need to be examined with an openness to major changes in the DSM-V.

  4. Individual Performance

    DEFF Research Database (Denmark)

    Andersen, Lotte Bøgh; Heinesen, Eskil; Pedersen, Lene Holm

    2016-01-01

    Performance is perhaps the most central concept in public administration research, and this article discusses theoretically and investigates empirically how we can obtain more consistent performance measures. Theoretically, we combine existing arguments in public administration with institutional...... theory and the sociology of professions. Empirically, we ask whether different measures of individual performance produce different results. The investigated performance measures vary with regard to risk of common data source bias, standardization of assessment criteria, and external verification...... of the assessment. Our investigated explanatory variables are intrinsic motivation, public service motivation, and job satisfaction. Combining survey and administrative data for 747 lower secondary school teachers (teaching 5,679 students in 85 schools), we analyze 4 different measures of the same performance...

  5. Natural phenomena hazards site characterization criteria

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    The criteria and recommendations in this standard shall apply to site characterization for the purpose of mitigating Natural Phenomena Hazards (wind, floods, landslide, earthquake, volcano, etc.) in all DOE facilities covered by DOE Order 5480.28. Criteria for site characterization not related to NPH are not included unless necessary for clarification. General and detailed site characterization requirements are provided in areas of meteorology, hydrology, geology, seismology, and geotechnical studies.

  6. MODELLING THE FINANCIAL PERFORMANCE OF THE INDUSTRIAL ENTERPRISES – CASE OF LIGHT, WINE AND MACHINERY INDUSTRIES

    Directory of Open Access Journals (Sweden)

    Nadejda BOTNARI

    2016-01-01

    Full Text Available The financial performance reflects the success in realization of financial objectives or in value creation. The evaluation of financial performance represents a stringent necessity for enterprise’s development, thus the estimated level of financial performance allows establishing the directions of enterprise activity improvement. The researchers use different methods of financial performance evaluation depending on their research objects. This paper aims to adapt the econometric model of financial performance evaluation for industrial enterprises.

  7. Rett Syndrome: Revised Diagnostic Criteria and Nomenclature

    Science.gov (United States)

    Neul, Jeffrey L.; Kaufmann, Walter E.; Glaze, Daniel G.; Christodoulou, John; Clarke, Angus J.; Bahi-Buisson, Nadia; Leonard, Helen; Bailey, Mark E. S.; Schanen, N. Carolyn; Zappella, Michele; Renieri, Alessandra; Huppke, Peter; Percy, Alan K.

    2010-01-01

    Objective Rett syndrome (RTT) is a severe neurodevelopmental disease that affects approximately 1 in 10,000 live female births and is often caused by mutations in Methyl-CpG-binding protein 2 (MECP2). Despite distinct clinical features, the accumulation of clinical and molecular information in recent years has generated considerable confusion regarding the diagnosis of RTT. The purpose of this work was revise and clarify 2002 consensus criteria for the diagnosis of RTT in anticipation of treatment trials. Method RettSearch members, representing the majority of the international clinical RTT specialists, participated in an iterative process to come to a consensus on a revised and simplified clinical diagnostic criteria for RTT. Results The clinical criteria required for the diagnosis of classic and atypical RTT were clarified and simplified. Guidelines for the diagnosis and molecular evaluation of specific variant forms of RTT were developed. Interpretation These revised criteria provide clarity regarding the key features required for the diagnosis of RTT and reinforce the concept that RTT is a clinical diagnosis based on distinct clinical criteria, independent of molecular findings. We recommend that these criteria and guidelines be utilized in any proposed clinical research. PMID:21154482

  8. 76 FR 46814 - Medicare Program; Evaluation Criteria and Standards for Quality Improvement Program Contracts...

    Science.gov (United States)

    2011-08-03

    ...] Medicare Program; Evaluation Criteria and Standards for Quality Improvement Program Contracts (10th... evaluate the effectiveness and efficiency of Quality Improvement Organizations (QIOs) that will enter into... and efficient performance of contract obligations by the Quality Improvement Organizations (QIOs), and...

  9. A hybrid fuzzy multi-criteria decision making model for green ...

    African Journals Online (AJOL)

    , quality and environmental performance. Hence,supplier selection is significant factor in supply chain success. Supplier selection is a multi-criteria problem, which involve uncertain qualitative and quantitative data. Thus, the aim of this paper ...

  10. Waste-acceptance criteria for greater-confinement disposal

    International Nuclear Information System (INIS)

    Gilbert, T.L.; Meshkov, N.K.

    1986-01-01

    A methodology for establishing waste-acceptance criteria based on quantitative performance factors that characterize the confinement capabilities of a waste-disposal site and facility has been developed. The methodology starts from the basic objective of protecting public health and safety by providing assurance that dispsoal of the waste will not result in a radiation dose to any member of the general public, in either the short or long term, in excess of an established basic dose limit. The method is based on an explicit, straightforward, and quantitative relationship among individual risk, confinement capabilities, and waste characteristics. A key aspect of the methodology is the introduction of a confinement factor that characterizes the overall confinement capability of a particular facility and can be used for quantitative assessments of the performance of different disposal sites and facilities, as well as for establishing site-specific waste-acceptance criteria. Confinement factors are derived by means of site-specific pathway analyses. They make possible a direct and simple conversion of a basic dose limit into waste-acceptance criteria, specified as concentration limits on radionuclides in the waste streams and expressed in quantitative form as a function of parameters that characterize the site, facility design, waste containers, and waste form. Waste-acceptance criteria can be represented visually as activity/time plots for various waste streams. These plots show the concentrations of radionuclides in a waste stream as a function of time and permit a visual, quantitative assessment of long-term performance, relative risks from different radionuclides in the waste stream, and contributions from ingrowth. 13 refs

  11. Utilize common criteria methodology for secure ubiquitous healthcare environment.

    Science.gov (United States)

    Yu, Yao-Chang; Hou, Ting-Wei

    2012-06-01

    RFID technology is widely used in healthcare environments to ensure patient safety. Therefore, the testing of RFID tags, such as performance tests and security evaluations, is necessary to ensure inter-operational functional compatibility with standards. A survey of the literature shows that while standards that are around RFID performance tests have been addressed, but the same is not true for security evaluations. Therefore, in this paper, we introduce the Common Criteria security evaluation methodology, also known as ISO/IEC 15408, for the security evaluation of RFID tags and propose a framework as a minimal requirement for RFID tags to improve security assurance.

  12. Seismic design and evaluation criteria for DOE facilities (DOE-STD-1020-XX)

    International Nuclear Information System (INIS)

    Short, S.A.; Kennedy, R.P.; Murray, R.C.

    1993-01-01

    Seismic design and evaluation criteria for DOE facilities are provided in DOE-STD-1020-XX. The criteria include selection of design/evaluation seismic input from probabilistic seismic hazard curves combined with commonly practiced deterministic response evaluation methods and acceptance criteria with controlled levels of conservatism. Conservatism is intentionally introduced in specification of material strengths and capacities, in the allowance of limited inelastic behavior and by a seismic load factor. These criteria are based on the performance or risk goals specified in DOE 5480.28. Criteria have been developed following a graded approach for several performance goals ranging from that appropriate for normal-use facilities to that appropriate for facilities involving hazardous or critical operations. Performance goals are comprised of desired behavior and of the probability of not achieving that behavior. Following the seismic design/evaluation criteria of DOE-STD-1020-XX is sufficient to demonstrate that the probabilistic performance or risk goals are achieved. The criteria are simple procedures but with a sound, rigorous basis for the achievement of goals

  13. Preliminary radiation criteria and nuclear analysis for ETF

    International Nuclear Information System (INIS)

    Engholm, B.A.

    1980-09-01

    Preliminary biological and materials radiation dose criteria for the Engineering Test Facility are described and tabulated. In keeping with the ETF Mission Statement, a key biological dose criterion is a 24-hour shutdown dose rate of 2 mrem/hr on the surface of the outboard bulk shield. Materials dose criteria, which primarily govern the inboard shield design, include 10 9 rads exposure limit to epoxy insulation, 3 x 10 -4 dpa damage to the TF coil copper stabilizer, and a total nuclear heating rate of 5 kW in the inboard TF coils. Nuclear analysis performed during FY 80 was directed primarily at the inboard and outboard bulk shielding, and at radiation streaming in the neutral beam drift ducts. Inboard and outboard shield thicknesses to achieve the biological and materials radiation criteria are 75 cm inboard and 125 cm outboard, the configuration consisting of alternating layers of stainless steel and borated water. The outboard shield also includes a 5 cm layer of lead. NBI duct streaming analyses performed by ORNL and LASL will play a key role in the design of the duct and NBI shielding in FY 81. The NBI aluminum cryopanel nuclear heating rate during the heating cycle is about 1 milliwatt/cm 3 , which is far less than the permissible limit

  14. Photovoltaic system criteria documents. Volume 3: Environmental issues and evaluation criteria for photovoltaic applications

    Science.gov (United States)

    Koenig, John C.; Billitti, Joseph W.; Tallon, John M.

    1979-01-01

    The environmental issues and evaluation criteria relating to the suitability of sites proposed for photovoltaic (PV) system deployment are identified. The important issues are defined, briefly discussed and then developed into evaluation criteria. System designers are provided with information on the environmental sensitivity of PV systems in realistic applications, background material which indicates the applicability of the siting issues identified, and evaluation criteria are defined to facilitate the selection of sites that maximize PV system operation.

  15. Use of simple transport equations to estimate waste package performance requirements

    International Nuclear Information System (INIS)

    Wood, B.J.

    1982-01-01

    A method of developing waste package performance requirements for specific nuclides is described. The method is based on: Federal regulations concerning permissible concentrations in solution at the point of discharge to the accessible environment; a simple and conservative transport model; baseline and potential worst-case release scenarios. Use of the transport model enables calculation of maximum permissible release rates within a repository in basalt for each of the scenarios. The maximum permissible release rates correspond to performance requirements for the engineered barrier system. The repository was assumed to be constructed in a basalt layer. For the cases considered, including a well drilled into an aquifer 1750 m from the repository center, little significant advantage is obtained from a 1000-yr as opposed to a 100-yr waste package. A 1000-yr waste package is of importance only for nuclides with half-lives much less than 100 yr which travel to the accessible environment in much less than 1000 yr. Such short travel times are extremely unlikely for a mined repository. Among the actinides, the most stringent maximum permissible release rates are for 236 U and 234 U. A simple solubility calculation suggests, however, that these performance requirements can be readily met by the engineered barrier system. Under the reducing conditions likely to occur in a repository located in basalt, uranium would be sufficiently insoluble that no solution could contain more than about 0.01% of the maximum permissible concentration at saturation. The performance requirements derived from the one-dimensional modeling approach are conservative by at least one to two orders of magnitude. More quantitative three-dimensional modeling at specific sites should enable relaxation of the performance criteria derived in this study. 12 references, 8 figures, 8 tables

  16. Clinical characteristics of migraine and episodic tension-type headache in relation to old and new diagnostic criteria

    DEFF Research Database (Denmark)

    Iversen, Helle Klingenberg; Langemark, M; Andersson, P G

    1990-01-01

    Eighty-one patients were diagnosed as having migraine, tension headache or both according to previously used criteria. Then we performed a standardized interview to determine the frequency and severity of headache characteristics used in the new operational diagnostic criteria of the International...... Headache Society (IHS). In every patient the original diagnosis fulfilled also the IHS criteria, but in 9 patients the criteria were only fulfilled in half or less of the attacks, and applying the IHS criteria they also achieved an additional diagnosis. In one patient these attacks did not fulfill the pain...

  17. Non-linear electromechanical behaviour of piezoelectric bimorph actuators: influence on performance and lifetime

    NARCIS (Netherlands)

    Ende, D.A. van den; Bos, B.; Groen, W.A.

    2009-01-01

    Piezoelectric bimorph bender actuators find application number of areas, ranging from automotive to health care. High voltage operation in harsh environments poses ever more stringent demands on functionality and lifetime. In these high performance benders, the trade-off between functionality and

  18. Objective Motion Cueing Criteria Investigation Based on Three Flight Tasks

    Science.gov (United States)

    Zaal, Petrus M. T.; Schroeder, Jeffery A.; Chung, William W.

    2015-01-01

    This paper intends to help establish fidelity criteria to accompany the simulator motion system diagnostic test specified by the International Civil Aviation Organization. Twelve air- line transport pilots flew three tasks in the NASA Vertical Motion Simulator under four different motion conditions. The experiment used three different hexapod motion configurations, each with a different tradeoff between motion filter gain and break frequency, and one large motion configuration that utilized as much of the simulator's motion space as possible. The motion condition significantly affected: 1) pilot motion fidelity ratings, and sink rate and lateral deviation at touchdown for the approach and landing task, 2) pilot motion fidelity ratings, roll deviations, maximum pitch rate, and number of stick shaker activations in the stall task, and 3) heading deviation after an engine failure in the takeoff task. Significant differences in pilot-vehicle performance were used to define initial objective motion cueing criteria boundaries. These initial fidelity boundaries show promise but need refinement.

  19. Dose Evaluation and Quality Criteria in Dental Radiology

    Energy Technology Data Exchange (ETDEWEB)

    Gori, C.; Rossi, F.; Stecco, A.; Villari, N.; Zatelli, G

    2000-07-01

    Radioprotection in dental radiology is of particular interest in the framework of the Revised Medical Exposure Directive for the great number of examinations involving the adult as well as the paediatric population (Article 9: Special Practice). The present study is intended to find the quality criteria of orthodontic imaging and for evaluating the dose absorbed within the dental and maxillary volume in connection with radiological examinations performed with either spiral CT, dental panoramic tomography or teleradiography. The X ray dose to organs sited in the body, neck, ocular and intracranial area was measured using lithium fluoride dosemeters, positioned in a Rando phantom. Quality criteria have been established by an expert radiologist considering the diagnostic information obtained in the images. The dosimetric data obtained were comparable with other authors', although with some differences due to technical characteristics. These result data are useful for choosing the patient's diagnostic path, considering the radiobiological risk associated with increasing orthodontic imaging. (author)

  20. Dose Evaluation and Quality Criteria in Dental Radiology

    International Nuclear Information System (INIS)

    Gori, C.; Rossi, F.; Stecco, A.; Villari, N.; Zatelli, G.

    2000-01-01

    Radioprotection in dental radiology is of particular interest in the framework of the Revised Medical Exposure Directive for the great number of examinations involving the adult as well as the paediatric population (Article 9: Special Practice). The present study is intended to find the quality criteria of orthodontic imaging and for evaluating the dose absorbed within the dental and maxillary volume in connection with radiological examinations performed with either spiral CT, dental panoramic tomography or teleradiography. The X ray dose to organs sited in the body, neck, ocular and intracranial area was measured using lithium fluoride dosemeters, positioned in a Rando phantom. Quality criteria have been established by an expert radiologist considering the diagnostic information obtained in the images. The dosimetric data obtained were comparable with other authors', although with some differences due to technical characteristics. These result data are useful for choosing the patient's diagnostic path, considering the radiobiological risk associated with increasing orthodontic imaging. (author)