WorldWideScience

Sample records for stringent environmental regulations

  1. Is ionizing radiation regulated more stringently than chemical carcinogens

    International Nuclear Information System (INIS)

    Travis, C.C.; Pack, S.R.; Hattemer-Frey, H.A.

    1989-01-01

    It is widely believed that United States government agencies regulate exposure to ionizing radiation more stringently than exposure to chemical carcinogens. It is difficult to verify this perception, however, because chemical carcinogens and ionizing radiation are regulated using vastly different strategies. Chemical carcinogens are generally regulated individually. Regulators consider the risk of exposure to one chemical rather than the cumulative radiation exposure from all sources. Moreover, standards for chemical carcinogens are generally set in terms of quantities released or resultant environmental concentrations, while standards for ionizing radiation are set in terms of dose to the human body. Since chemicals and ionizing radiation cannot be compared on the basis of equal dose to the exposed individual, standards regulating chemicals and ionizing radiation cannot be compared directly. It is feasible, however, to compare the two sets of standards on the basis of equal risk to the exposed individual, assuming that standards for chemicals and ionizing radiation are equivalent if estimated risk levels are equitable. This paper compares risk levels associated with current standards for ionizing radiation and chemical carcinogens. The authors do not attempt to determine whether either type of risk is regulated too stringently or not stringently enough but endeavor only to ascertain if ionizing radiation is actually regulated more strictly than chemical carcinogens

  2. The stringent response regulates adaptation to darkness in the cyanobacterium Synechococcus elongatus.

    Science.gov (United States)

    Hood, Rachel D; Higgins, Sean A; Flamholz, Avi; Nichols, Robert J; Savage, David F

    2016-08-16

    The cyanobacterium Synechococcus elongatus relies upon photosynthesis to drive metabolism and growth. During darkness, Synechococcus stops growing, derives energy from its glycogen stores, and greatly decreases rates of macromolecular synthesis via unknown mechanisms. Here, we show that the stringent response, a stress response pathway whose genes are conserved across bacteria and plant plastids, contributes to this dark adaptation. Levels of the stringent response alarmone guanosine 3'-diphosphate 5'-diphosphate (ppGpp) rise after a shift from light to dark, indicating that darkness triggers the same response in cyanobacteria as starvation in heterotrophic bacteria. High levels of ppGpp are sufficient to stop growth and dramatically alter many aspects of cellular physiology, including levels of photosynthetic pigments and polyphosphate, DNA content, and the rate of translation. Cells unable to synthesize ppGpp display pronounced growth defects after exposure to darkness. The stringent response regulates expression of a number of genes in Synechococcus, including ribosomal hibernation promoting factor (hpf), which causes ribosomes to dimerize in the dark and may contribute to decreased translation. Although the metabolism of Synechococcus differentiates it from other model bacterial systems, the logic of the stringent response remains remarkably conserved, while at the same time having adapted to the unique stresses of the photosynthetic lifestyle.

  3. Emission reductions in transition economies: A result of output contraction or more stringent environmental policy?

    Energy Technology Data Exchange (ETDEWEB)

    Zugravu, N.; Millock, K. [University Paris 1 Pantheon-Sorbonne (France); Duchene, G. [University Paris 12, Creteil (France)

    2007-07-01

    Countries in Central and Eastern Europe significantly reduced their CO{sub 2} emissions between 1996 and 2001. Was this emission reduction just the fortuitous result of the major economic transformation undergone by those countries in the transition away from a centralized plan economy? Or is the emission reduction rather a result of more stringent environmental policy? The objective of the article is to answer this question through a model of the relation between environmental quality and enforcement, on the one hand, and environmental quality and economic growth, on the other hand. The authors develop structural equations for the demand (emissions) and supply (environmental stringency) of pollution. The supply equation takes into account the institutional quality of the country (control of corruption and political stability) as well as consumer preferences for environmental quality, as proxied by per capita revenue and unemployment. The system is estimated by three stage least squares on a sample of three groups of countries for comparative analysis: Central and Eastern European countries, Western European countries, and emerging economies. The results indicate that, all else equal, the scale effect on its own would have increased industrial CO{sub 2} emissions in the Central and Eastern European countries in the sample by 44.6% between 1996 and 2001. The composition effect accounted for a corresponding reduction in emissions by 16%. The technique effect had the largest marginal impact, corresponding to a 37.4% reduction in emissions.

  4. The Stringent Response Promotes Antibiotic Resistance Dissemination by Regulating Integron Integrase Expression in Biofilms

    Directory of Open Access Journals (Sweden)

    Emilie Strugeon

    2016-08-01

    Full Text Available Class 1 integrons are genetic systems that enable bacteria to capture and express gene cassettes. These integrons, when isolated in clinical contexts, most often carry antibiotic resistance gene cassettes. They play a major role in the dissemination of antibiotic resistance among Gram-negative bacteria. The key element of integrons is the integrase, which allows gene cassettes to be acquired and shuffled. Planktonic culture experiments have shown that integrase expression is regulated by the bacterial SOS response. In natural settings, however, bacteria generally live in biofilms, which are characterized by strong antibiotic resilience and by increased expression of stress-related genes. Here, we report that under biofilm conditions, the stringent response, which is induced upon starvation, (i increases basal integrase and SOS regulon gene expression via induction of the SOS response and (ii exerts biofilm-specific regulation of the integrase via the Lon protease. This indicates that biofilm environments favor integron-mediated acquisition of antibiotic resistance and other adaptive functions encoded by gene cassettes.

  5. Stringency of environmental regulation and aquaculture growth

    DEFF Research Database (Denmark)

    Gedefaw Abate, Tenaw; Nielsen, Rasmus; Tveterås, Ragnar

    2016-01-01

    remarkable growth in aquaculture while others have stagnated or even declined have not been determined. In this article, we investigate whether environmental regulations have an impact on aquaculture growth. Using a cross-country regression analysis, we show that stringent environmental regulations...... contributed to lower growth rates and that these countries are falling behind emerging and developing economies that have more lenient environmental regulations....

  6. Air Quality and Health Benefits of China's Recent Stringent Environmental Policy

    Science.gov (United States)

    Zheng, Y.; Xue, T.; Zhang, Q.; Geng, G.; He, K.

    2016-12-01

    Aggressive emission control measures were taken by China's central and local governments after the promulgation of the "Air Pollution Prevention and Control Action Plan" in 2013. We evaluated the air quality and health benefits of this ever most stringent air pollution control policy during 2013-2015 by utilizing a two-stage data fusion model and newly-developed cause-specific integrated exposure-response functions (IER) developed for the Global Burden of Disease (GBD). The two-stage data fusion model predicts spatiotemporal continuous PM2.5 (particulate matter with aerodynamic diameter less than 2.5 µm) concentrations by integrating satellite-derived aerosol optical depth (AOD) measurements, PM2.5 concentrations from measurement and air quality model, and other ancillary information. During the years of analysis, PM2.5 concentration dropped significantly on national average and over heavily polluted regions as identified by Mann-Kendall analysis. The national PM2.5-attributable mortality decreased by 72.8 (95% CI: 59.4, 85.2) thousand (6%) from 1.23 (95% CI: 1.06, 1.39) million in 2013 to 1.15 (95% CI: 0.98, 1.31) million in 2015 due to considerable reduction (i.e. 18%) of population-weighted PM2.5 from 61.4 to 50.5 µg/m3. Meteorological variations between 2013 and 2015 were estimated to raise the PM2.5 levels by 0.24 µg/m3 and national mortality by 2.1 (95% CI: 1.6, 2.6) thousand through sensitivity tests, which implies the dominant role of anthropogenic impacts on PM2.5 abatement and attributable mortality reduction. Our study affirms the effectiveness of China's recent air quality policy, however, due to the possible supralinear shape of C-R functions, health benefits induced by air quality improvement in these years are limited. We therefore appeal for continuous implementation of current policies and further stringent measures from both air quality improvement and public health protection perspectives.

  7. Direct-to-physician and direct-to-consumer advertising: Time to have stringent regulations.

    Science.gov (United States)

    Kannan, S; Gowri, S; Tyagi, V; Kohli, S; Jain, R; Kapil, P; Bhardwaj, A

    2015-01-01

    the opinion regarding DTCA, 69.9% physicians had a patient discussing DTCA that was clinically inappropriate. One hundred (64.5%) out of 155 physicians opined that DTCA encourage patients to attend physicians regarding preventive healthcare. On the contrary, 82/155 (52.9%) physicians felt that DTCA would damage the same. Similarly, 69 out of the total 100 patients felt that drug advertisements aid them to have better discussions with their treating physicians. Surprisingly, a large majority (91/100) were of the opinion that only safe drugs are allowed to be advertised. To conclude, from the findings of this study both the physicians and patients should be cautious and not overzealous while dealing with drug advertisements or promotional literature. More stringent scrutiny and issue of WLs or blacklisting of indulging pharmaceutical companies are mandatory by the regulatory agency to contain the same.

  8. Inducible Expression of Agrobacterium Virulence Gene VirE2 for Stringent Regulation of T-DNA Transfer in Plant Transient Expression Systems.

    Science.gov (United States)

    Denkovskienė, Erna; Paškevičius, Šarūnas; Werner, Stefan; Gleba, Yuri; Ražanskienė, Aušra

    2015-11-01

    Agrotransfection with viral vectors is an effective solution for the transient production of valuable proteins in plants grown in contained facilities. Transfection methods suitable for field applications are desirable for the production of high-volume products and for the transient molecular reprogramming of plants. The use of genetically modified (GM) Agrobacterium strains for plant transfections faces substantial biosafety issues. The environmental biosafety of GM Agrobacterium strains could be improved by regulating their T-DNA transfer via chemically inducible expression of virE2, one of the essential Agrobacterium virulence genes. In order to identify strong and stringently regulated promoters in Agrobacterium strains, we evaluated isopropyl-β-d-thiogalactoside-inducible promoters Plac, Ptac, PT7/lacO, and PT5/lacOlacO and cumic acid-inducible promoters PlacUV5/CuO, Ptac/CuO, PT5/CuO, and PvirE/CuO. Nicotiana benthamiana plants were transfected with a virE2-deficient A. tumefaciens strain containing transient expression vectors harboring inducible virE2 expression cassettes and containing a marker green fluorescent protein (GFP) gene in their T-DNA region. Evaluation of T-DNA transfer was achieved by counting GFP expression foci on plant leaves. The virE2 expression from cumic acid-induced promoters resulted in 47 to 72% of wild-type T-DNA transfer. Here, we present efficient and tightly regulated promoters for gene expression in A. tumefaciens and a novel approach to address environmental biosafety concerns in agrobiotechnology.

  9. Stringent and reproducible tetracycline-regulated transgene expression by site-specific insertion at chromosomal loci with pre-characterised induction characteristics

    Directory of Open Access Journals (Sweden)

    Papanastasiou Antigoni M

    2007-05-01

    Full Text Available Abstract Background The ability to regulate transgene expression has many applications, mostly concerning the analysis of gene function. Desirable induction characteristics, such as low un-induced expression, high induced expression and limited cellular heterogeneity, can be seriously impaired by chromosomal position effects at the site of transgene integration. Many clones may therefore need to be screened before one with optimal induction characteristics is identified. Furthermore, such screens must be repeated for each new transgene investigated, and comparisons between clones with different transgenes is complicated by their different integration sites. Results To circumvent these problems we have developed a "screen and insert" strategy in which clones carrying a transgene for a fluorescent reporter are first screened for those with optimal induction characteristics. Site-specific recombination (SSR is then be used repeatedly to insert any new transgene at the reporter transgene locus of such clones so that optimal induction characteristics are conferred upon it. Here we have tested in a human fibrosarcoma cell line (HT1080 two of many possible implementations of this approach. Clones (e.g. Rht14-10 in which a GFP reporter gene is very stringently regulated by the tetracycline (tet transactivator (tTA protein were first identified flow-cytometrically. Transgenes encoding luciferase, I-SceI endonuclease or Rad52 were then inserted by SSR at a LoxP site adjacent to the GFP gene resulting stringent tet-regulated transgene expression. In clone Rht14-10, increases in expression from essentially background levels (+tet to more than 104-fold above background (-tet were reproducibly detected after Cre-mediated insertion of either the luciferase or the I-SceI transgenes. Conclusion Although previous methods have made use of SSR to integrate transgenes at defined sites, none has effectively combined this with a pre-selection step to identify

  10. Dual Regulation of Bacillus subtilis kinB Gene Encoding a Sporulation Trigger by SinR through Transcription Repression and Positive Stringent Transcription Control

    Directory of Open Access Journals (Sweden)

    Yasutaro Fujita

    2017-12-01

    Full Text Available It is known that transcription of kinB encoding a trigger for Bacillus subtilis sporulation is under repression by SinR, a master repressor of biofilm formation, and under positive stringent transcription control depending on the adenine species at the transcription initiation nucleotide (nt. Deletion and base substitution analyses of the kinB promoter (PkinB region using lacZ fusions indicated that either a 5-nt deletion (Δ5, nt -61/-57, +1 is the transcription initiation nt or the substitution of G at nt -45 with A (G-45A relieved kinB repression. Thus, we found a pair of SinR-binding consensus sequences (GTTCTYT; Y is T or C in an inverted orientation (SinR-1 between nt -57/-42, which is most likely a SinR-binding site for kinB repression. This relief from SinR repression likely requires SinI, an antagonist of SinR. Surprisingly, we found that SinR is essential for positive stringent transcription control of PkinB. Electrophoretic mobility shift assay (EMSA analysis indicated that SinR bound not only to SinR-1 but also to SinR-2 (nt -29/-8 consisting of another pair of SinR consensus sequences in a tandem repeat arrangement; the two sequences partially overlap the ‘-35’ and ‘-10’ regions of PkinB. Introduction of base substitutions (T-27C C-26T in the upstream consensus sequence of SinR-2 affected positive stringent transcription control of PkinB, suggesting that SinR binding to SinR-2 likely causes this positive control. EMSA also implied that RNA polymerase and SinR are possibly bound together to SinR-2 to form a transcription initiation complex for kinB transcription. Thus, it was suggested in this work that derepression of kinB from SinR repression by SinI induced by Spo0A∼P and occurrence of SinR-dependent positive stringent transcription control of kinB might induce effective sporulation cooperatively, implying an intimate interplay by stringent response, sporulation, and biofilm formation.

  11. The impact of environmental regulations on drilling fluid technology

    International Nuclear Information System (INIS)

    Clark, R.K.

    1994-01-01

    A multitude of new drilling fluid products, systems, and treatment processes have been developed in recent years in response to increasingly stringent environmental regulations. Many fluid additives and systems that once played a major role in the drilling industry are little used today or are no longer available. New water-base mud systems are approaching the performance levels typical of conventional oil-base muds, levels largely achieved by the new synthetic-base fluids. However, these new drilling fluids do not have the adverse environmental impact associated with oil-base systems when waste fluids and cuttings are discarded. 65 refs., 3 tabs

  12. addressing environmental contamination through market regulations

    African Journals Online (AJOL)

    RAYAN_

    environmental releases from new and existing chemical substances, which amounts to, if not more stringent, than ... environment.1 Though the mere detection of a chemical does not amount to risk per se, its presence in ... wildlife, water, and sediment) for specific classes of chemicals, particularly those that are persistent in ...

  13. Environmental regulation and the export dynamics of energy technologies

    International Nuclear Information System (INIS)

    Costantini, Valeria; Crespi, Francesco

    2008-01-01

    The pollution haven hypothesis affirms that an open market regime will encourage the flow of low-technology polluting industries towards developing countries because of potential comparative advantages related to low environmental standards. In contrast, the hypothesis suggested by Porter and van der Linde claims that innovating firms operate in a dynamic competitive situation which allows global diffusion of environmental-friendly technologies. Environmental regulation may represent a relevant mechanism through which technological change is induced. In this way, countries that are subject to more stringent environmental regulations may become net exporters of environmental technologies. This paper provides new evidence on the evolution of export flows of environmental technologies across different countries for the energy sector. Advanced economies, particularly the European Union, have increasingly focused on the role of energy policies as tools for sustaining the development path. The Kyoto Protocol commitments, together with growing import dependence on energy products, have brought attention to the analysis of innovation processes in this specific sector. The analysis uses a gravity model in order to test the determinants and the transmission channels through which environmental technologies for renewable energies and energy efficiency are exported to advanced and developing countries. Our results are consistent with the Porter and van der Linde hypothesis where environmental regulation represents a significant source of comparative advantages. What strongly emerges is that the stringency of environmental regulation supplemented by the strength of the National Innovation System is a crucial driver of export performance in the field of energy technologies. (author)

  14. Environmental considerations and regulations

    International Nuclear Information System (INIS)

    Blanco, R.E.

    1976-01-01

    Methods used to control the radiological impact of the nuclear fuel cycle are described. This control is exercised through the application of a series of federal laws and regulations that are used as the basis for licensing nuclear facilities. The control is exercised more directly by the use of radwaste treatment equipment at the nuclear facilities to limit the release of radioactive materials. Federal laws and regulations are summarized and their applications in licensing actions are discussed. Radiological doses from materials released from licensed facilities are compared with doses from natural background. A series of cost/benefit engineering surveys are being made to determine the cost and effectiveness of radwaste systems for decreasing the release of radioactive materials from model fuel cycle facilities and to determine the benefits in terms of reduction in dose commitment to individuals and populations in surrounding areas

  15. Ownership and environmental regulation: Evidence from the European electricity industry

    International Nuclear Information System (INIS)

    Clò, Stefano; Ferraris, Matteo; Florio, Massimo

    2017-01-01

    The paper investigates how ownership affects the environmental performance in developed countries where environmental regulation is introduced in the form of market-based instrument. By looking at a cross-country panel dataset of 29 power markets around Europe over the period 1990–2012, we find empirical evidence that an increase of public ownership, as measured by the OECD ETCR index, is associated with a reduction of both greenhouse gas emissions and carbon intensity. We also find that the implementation of the European Emissions Trading Scheme (ETS) had a limited impact on emissions' reduction due to lax allocation of allowances. The positive effect of public ownership on environmental performance has been significant even after the introduction of the ETS, giving additional incentives to mitigate emissions when the ETS cap was not stringent enough. This evidence suggests that government control over power companies in Europe can has created idiosyncratic incentives to improve environmental quality, complementing environmental regulation in the achievement of environmental goals when the latter was absent or sub-optimal. - Highlights: • We analyse the power industry's environmental performance in 29 European countries. • Public ownership is associated with lower emissions than private ownership. • Mixed oligopoly is superior to private oligopoly in environmental terms. • The ETS had a limited impact on emissions' reduction due to over-allocation. • Public ownership mitigates the effects of sub-optimal environmental regulation.

  16. Federal Environmental Regulations Impacting Hydrocarbon Exploration, Drilling, and Production Operations

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, Herbert B.; Johnson, William I.

    1999-04-27

    Waste handling and disposal from hydrocarbon exploration, drilling, and production are regulated by the US Environmental Protection Agency (EPA) through federal and state regulations and/or through implementation of federal regulations. Some wastes generated in these operations are exempt under the Resource Conservation and Recovery Act (RCRA) but are not exempt under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), Superfund Amendments and Reauthorization Act (SARA), and other federal environmental laws. Exempt wastes remain exempt only if they are not mixed with hazardous wastes or hazardous substances. Once mixture occurs, the waste must be disposed as a hazardous material in an approved hazardous waste disposal facility. Before the Clean Air Act as amended in 1990, air emissions from production, storage, steam generation, and compression facilities associated with hydrocarbon exploration, drilling, and production industry were not regulated. A critical proposed regulatory change which will significantly effect Class II injection wells for disposal of produced brine and injection for enhanced oil recovery is imminent. Federal regulations affecting hydrocarbon exploration, drilling and production, proposed EPA regulatory changes, and a recent significant US Court of Appeals decision are covered in this report. It appears that this industry will, in the future, fall under more stringent environmental regulations leading to increased costs for operators.

  17. Environmental Regulation, Industrial Heterogeneity and Value Compensation

    OpenAIRE

    Chen Lisha; Ding Changqing

    2017-01-01

    This article divided environmental regulation tools into market-oriented environmental regulation, environmental administrative control and environmental pollution regulation, divided enterprises into pollution intensive and clean production enterprises. Take Chinese manufacturing listed companies as research object, through panel data analysis, this article measured short-term and long-term value compensation effect and the possible existence of the threshold effect and cumulative effect of ...

  18. Industrial Innovation and Environmental Regulation: Developing ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    What role should governments play in protecting the environment and controlling the environmental impacts of industry? Do regulations benefit the environment, and how do they affect industrial innovation?

  19. Environmentally Regulated Facilities in Iowa

    Data.gov (United States)

    Iowa State University GIS Support and Research Facility — A unique record for each facility site with an environmental interest by DNR (such as permits). This brings together core environmental information in one place for...

  20. Circuitry linking the Csr and stringent response global regulatory systems.

    Science.gov (United States)

    Edwards, Adrianne N; Patterson-Fortin, Laura M; Vakulskas, Christopher A; Mercante, Jeffrey W; Potrykus, Katarzyna; Vinella, Daniel; Camacho, Martha I; Fields, Joshua A; Thompson, Stuart A; Georgellis, Dimitris; Cashel, Michael; Babitzke, Paul; Romeo, Tony

    2011-06-01

    CsrA protein regulates important cellular processes by binding to target mRNAs and altering their translation and/or stability. In Escherichia coli, CsrA binds to sRNAs, CsrB and CsrC, which sequester CsrA and antagonize its activity. Here, mRNAs for relA, spoT and dksA of the stringent response system were found among 721 different transcripts that copurified with CsrA. Many of the transcripts that copurified with CsrA were previously determined to respond to ppGpp and/or DksA. We examined multiple regulatory interactions between the Csr and stringent response systems. Most importantly, DksA and ppGpp robustly activated csrB/C transcription (10-fold), while they modestly activated csrA expression. We propose that CsrA-mediated regulation is relieved during the stringent response. Gel shift assays confirmed high affinity binding of CsrA to relA mRNA leader and weaker interactions with dksA and spoT. Reporter fusions, qRT-PCR and immunoblotting showed that CsrA repressed relA expression, and (p)ppGpp accumulation during stringent response was enhanced in a csrA mutant. CsrA had modest to negligible effects on dksA and spoT expression. Transcription of dksA was negatively autoregulated via a feedback loop that tended to mask CsrA effects. We propose that the Csr system fine-tunes the stringent response and discuss biological implications of the composite circuitry. © Published 2011. This article is a US Government work and is in the public domain in the USA.

  1. Cogeneration: Effects of environmental laws and regulations

    International Nuclear Information System (INIS)

    Dean, J.E.

    1994-01-01

    The new list of environmental regulations caused by the 1990 Clean Air Act Amendments and the expected effects of other environmental and related regulation on American industry is truly staggering. The author's brief overview is limited to the effects on utility customer power generation. In his opinion, the regulations favor the use of clean burning waste materials to generate steam and electricity. The environmental requirements for all industry are expected to tighten significantly. Some of the issues of interest are: timing; clean burning power generation; future projected issues (5 years or more); waste power cogeneration; and Internal Revenue guidelines

  2. Environmental regulations handbook for enhanced oil recovery

    Energy Technology Data Exchange (ETDEWEB)

    Madden, M.P. [National Inst. for Petroleum and Energy Research, Bartlesville, OK (United States); Blatchford, R.P.; Spears, R.B. [Spears and Associates, Inc., Tulsa, OK (United States)

    1991-12-01

    This handbook is intended to assist owners and operators of enhanced oil recovery (EOR) operations in acquiring some introductory knowledge of the various state agencies, the US Environmental Protection Agency, and the many environmental laws, rules and regulations which can have jurisdiction over their permitting and compliance activities. It is a compendium of summarizations of environmental rules. It is not intended to give readers specific working details of what is required from them, nor can it be used in that manner. Readers of this handbook are encouraged to contact environmental control offices nearest to locations of interest for current regulations affecting them.

  3. Environmental regulations handbook for enhanced oil recovery

    International Nuclear Information System (INIS)

    Madden, M.P.; Blatchford, R.P.; Spears, R.B.

    1991-12-01

    This handbook is intended to assist owners and operators of enhanced oil recovery (EOR) operations in acquiring some introductory knowledge of the various state agencies, the US Environmental Protection Agency, and the many environmental laws, rules and regulations which can have jurisdiction over their permitting and compliance activities. It is a compendium of summarizations of environmental rules. It is not intended to give readers specific working details of what is required from them, nor can it be used in that manner. Readers of this handbook are encouraged to contact environmental control offices nearest to locations of interest for current regulations affecting them

  4. Industrial Innovation and Environmental Regulation: Developing ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2007-03-01

    Mar 1, 2007 ... What role should governments play in protecting the environment and controlling the environmental impacts of industry? Do regulations benefit the environment, and how do they affect industrial innovation?

  5. Industrial Innovation and Environmental Regulation: Developing ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The purpose of environmental regulation has been to coerce producers of goods and services into internalizing environmental costs of production. ...... Replacement of PCB in transformers; replacement of heavy metals – lead, chromium and cadmium – in pigments, with calcium, strontium and barium counter ions.

  6. Pollution Under Environmental Regulation in Energy Markets

    CERN Document Server

    Gullì, Francesco

    2013-01-01

    Pollution Under Environmental Regulation in Energy Markets provides a study of environmental regulation when energy markets are imperfectly competitive. This theoretical treatment focuses on three relevant cases of energy markets. First, the residential space heating sector where hybrid regulation such as taxation and emissions trading together are possible. Second, the electricity market where transactions are organized in the form of multi-period auctions. Third, namely natural gas (input) and electricity (output) markets where there is combined imperfect competition in vertical related energy markets.   The development of free or low carbon technologies supported by energy policies, aiming at increasing security of supply, is also explored whilst considering competition policies that reduce market power in energy markets thus improving market efficiency. Pollution Under Environmental Regulation in Energy Markets discusses the key issues of whether imperfect competition can lessen the ability of environmen...

  7. Environmental regulation, asymmetric information and foreign ownership

    OpenAIRE

    Vislie,J.

    2001-01-01

    Regulating an export firm (or a homogeneous industry) with private information about emission technology is analysed, when the firm, owned partly by foreigners, has an option to bypass domestic regulation through costly relocation. If the firm chooses to relocate, it will set up a new plant in a region practicing environmental dumping, at a cost that is correlated with emission efficiency, so as to make the firm’s reservation utility type-dependent. We characterise the set of optimal contract...

  8. Environmental Regulations as Drivers of Materials Obsolescence

    Science.gov (United States)

    Scroggins, Sharon

    2010-01-01

    This slide presentation reviews the operations of the Principal Center for Regulatory Risk Analysis and Communication (RRAC-PC) and the impact of environmental regulations in making some materials obsolete. The center is NASA's resource for identifying and managing risks associated with changing environmental regulations. To this end the center acts as an regulatory early warning system, to review track and analyze emerging regulations, collaborate with the technical community on regulatory risk analysis and interpretation and to represent NASA's interests to the regulatory agencies. Regulations frequently result in making some materials unavailable forcing a change to another material. Processes may also be changed due to environmental regulations. For example some items that were sprayed with a chemical may now have to be painted or dipped with the chemical. Sometimes a regulation changes the use of a certain product, which does not affect the usage on Earth, but has significant implications in space. An example of this is the use of lead-free solders of basically tin, which don't appear to have any problem on Earth, but in space applications tin whiskers have resulted in several confirmed satellite failures.

  9. Industrial Innovation and Environmental Regulation : Developing ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Couverture du livre Industrial Innovation and Environmental Regulation : Developing Workable Solutions ... Il ressort de cet ouvrage que la complexité des relations entre l'environnement et l'économie n'admet pas de solutions uniformes et que le rôle des mesures de réglementation dans l'innovation environnementale doit ...

  10. Industrial Innovation and Environmental Regulation : Developing ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 mars 2007 ... Couverture du livre Industrial Innovation and Environmental Regulation : Developing Workable Solutions. Directeur(s) : Saeed Parto et ... L'Initiative des conseils subventionnaires de la recherche scientifique en Afrique subsaharienne remporte le prix de la diplomatie scientifique. L'Initiative des conseils ...

  11. Sustainable mining, local communities and environmental regulation

    Directory of Open Access Journals (Sweden)

    Kokko Kai

    2015-12-01

    Full Text Available Sustainable mining is an objective as well as a tool for balancing economic, social, and environmental considerations. Each of these three dimensions of mining – and sustainable development – has many components, some of which were chosen for closer study in the SUMILCERE project. While there is no single component that in itself provides a definitive argument for or against sustainable mining, the research reveals some that have proven valuable in the process of balancing the different dimensions of sustainability. In the SUMILCERE project, comparative studies enabled us to identify factors such as the following, which are essential when discussing the balancing in practice of the three dimensions of sustainable mining cited above: the framework and functionality of environmental regulation to protect the environment (environmental sustainability; competitiveness of the mining industry in light of environmental regulation and its enforcement (economic sustainability; public participation and the opportunities local communities have to influence their surroundings, as well as communities’ acceptance of projects (social sustainability before and during operations; and the protection of Sámi cultural rights in mining projects (social and cultural sustainability. Although each of the three dimensions of sustainability leaves room for discretion in the weight assigned to it, ecological sustainability, protected by smart environmental regulation and minimum standards, sets essential boundaries that leave no room for compromises. Economic and social sustainability are possible only within these limits. Details of the analyses in the Kolarctic area and accounts of the methods used can befound in the cited SUMILCERE articles.

  12. Environmental radiation exposure: Regulation, monitoring, and assessment

    International Nuclear Information System (INIS)

    Chen, S.Y.; Yu, C.; Hong, K.J.

    1991-01-01

    Radioactive releases to the environment from nuclear facilities constitute a public health concern. Protecting the public from such releases can be achieved through the establishment and enforcement of regulatory standards. In the United States, numerous standards have been promulgated to regulate release control at nuclear facilities. Most recent standards are more restrictive than those in the past and require that radioactivity levels be as low as reasonably achievable (ALARA). Environmental monitoring programs and radiological dose assessment are means of ensuring compliance with regulations. Environmental monitoring programs provide empirical information on releases, such as the concentrations of released radioactivity in environmental media, while radiological dose assessment provides the analytical means of quantifying dose exposures for demonstrating compliance

  13. Environmental Regulation Impacts on Eastern Interconnection Performance

    Energy Technology Data Exchange (ETDEWEB)

    Markham, Penn N [ORNL; Liu, Yilu [ORNL; Young II, Marcus Aaron [ORNL

    2013-07-01

    In the United States, recent environmental regulations will likely result in the removal of nearly 30 GW of oil and coal-fired generation from the power grid, mostly in the Eastern Interconnection (EI). The effects of this transition on voltage stability and transmission line flows have previously not been studied from a system-wide perspective. This report discusses the results of power flow studies designed to simulate the evolution of the EI over the next few years as traditional generation sources are replaced with environmentally friendlier ones such as natural gas and wind.

  14. Motivation for Compliance with Environmental Regulation

    DEFF Research Database (Denmark)

    Winter, Søren; May, Peter J.

    2001-01-01

    A combination of calculated, normative, and social motivations as well as awareness of rules and capacity to comply are thought to foster compliance with regulations. Hypotheses about these factors were tested with data concerning Danish farmers’ compliance with agro-environmental regulations....... Three key findings emerge: that farmers’ awareness of rules plays a critical role; that normative and social motivations are as influential as calculated motivations in enhancing compliance; and that inspectors’ enforcement style affects compliance differently from that posited in much of the literature...

  15. Environmental regulations on air pollution in China and their impact on infant mortality.

    Science.gov (United States)

    Tanaka, Shinsuke

    2015-07-01

    This study explores the impact of environmental regulations in China on infant mortality. In 1998, the Chinese government imposed stringent air pollution regulations, in one of the first large-scale regulatory attempts in a developing country. We find that the infant mortality rate fell by 20 percent in the treatment cities designated as "Two Control Zones." The greatest reduction in mortality occurred during the neonatal period, highlighting an important pathophysiologic mechanism, and was largest among infants born to mothers with low levels of education. The finding is robust to various alternative hypotheses and specifications. Further, a falsification test using deaths from causes unrelated to air pollution supports these findings. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Environmental regulations and their effects on the nuclear regulator

    International Nuclear Information System (INIS)

    McManus, J.G.

    1994-01-01

    Environmental regulations are discussed from the point of view of the Canadian Atomic Energy Control Board (AECB). The AECB's mission includes the environment, namely 'to ensure that the use of nuclear energy in Canada does not pose any undue risk to health, safety, security or the environment'. The regulatory process was governed by the Atomic Energy Control Act, which at the time of the conference was outdated and due for replacement by a new version, and by the Environmental Assessment and Review Process Guidelines Order, which was due to be replaced by the Canadian Environmental Assessment Act, still not in force at the time of the conference. Through court decisions, the Guidelines Order had effectively acquired statutory authority. Public hearings and review can result in some considerable delay to the approval of a project, yet the AECB has no choice but to ensure that the requirements of the Guidelines Order are fulfilled. Collaboration between the federal and provincial governments is very evident in Saskatchewan. Of six mining projects being considered by the AECB, five were being reviewed by a joint federal provincial panel. For the future, it was hoped that the new Atomic Energy Control Act would increase fines and the powers of inspectors, require financial guarantees for decommissioning, regularize cooperation with the provinces, and empower the AECB to hold hearings that could effectively substitute for those prescribed by the Canadian Environmental Assessment Act

  17. Manual: environmental impact statement and intervention regulation

    International Nuclear Information System (INIS)

    Neumann, K.

    1992-01-01

    In order to be able to fulfil also legally the important tasks of environmental protection and natural preservation in the last ten years numerous legal provisions have been issued. Many of these laws require that the environmental impact of projects and constructional measures is taken into account to a higher degree. Two important instruments in this connection are the impact statement and the intervention regulation of natural preservation. Their importance and consequences for the planning and realization of projects are until now not sufficiently know. This manual is to fill this gap. This booklet shall help builder-owners and investors to realize their building projects in a way which is compatible with the environment. For architects and planners information is given in this manual about the requirements to be fulfilled in the individual planning and licensing procedures. The booklet is structured in a way that builder-owners, consultants and authorities find quickly the information needed. (orig./KW) [de

  18. Environmental regulation of tourism: impact on business innovation

    DEFF Research Database (Denmark)

    Hjalager, Anne-Mette

    1998-01-01

    Tourism and environmental issues are particularly critical in small islands. This article compares environmental constraints and regulations on Bornholm, Isle of Wight and Mallorca.......Tourism and environmental issues are particularly critical in small islands. This article compares environmental constraints and regulations on Bornholm, Isle of Wight and Mallorca....

  19. Human exposure, health hazards, and environmental regulations

    International Nuclear Information System (INIS)

    Steinemann, Anne

    2004-01-01

    United States environmental regulations, intended to protect human health, generally fail to address major sources of pollutants that endanger human health. These sources are surprisingly close to us and within our control, such as consumer products and building materials that we use within our homes, workplaces, schools, and other indoor environments. Even though these indoor sources account for nearly 90% of our pollutant exposure, they are virtually unregulated by existing laws. Even pollutant levels found in typical homes, if found outdoors, would often violate federal environmental standards. This article examines the importance of human exposure as a way to understand and reduce effects of pollutants on human health. Results from exposure studies challenge traditional thinking about pollutant hazards, and reveal deficiencies in our patchwork of laws. And results from epidemiological studies, showing increases in exposure-related diseases, underscore the need for new protections. Because we cannot rely solely on regulations to protect us, and because health effects from exposures can develop insidiously, greater efforts are needed to reduce and prevent significant exposures before they occur. Recommendations include the development and use of safer alternatives to common products, public education on ways to reduce exposure, systematic monitoring of human exposure to pollutants, and a precautionary approach in decision-making

  20. The effect of environmental regulation on firms' competitive performance: the case of the building & construction sector in some EU regions.

    Science.gov (United States)

    Testa, Francesco; Iraldo, Fabio; Frey, Marco

    2011-09-01

    There is a considerable debate on the effects of environmental regulation on competitive performance. Based on survey data, this paper analyzes the two main research questions, derived from literature, on the links between environmental regulation and competitiveness, by focusing on firms operating in the building and construction sector, i.e.: 1) whether environmental policy stringency affects the competitive performance of firms in the building and construction sector 2) and how a specific form of environmental regulation (direct regulation, economic instruments and soft instruments) affects this performance? By applying a regression analysis, we find that a more stringent environmental regulation, measured by inspection frequency, provides a positive impulse for increasing investments in advanced technological equipment and innovative products and on business performance. Moreover, a well-designed "direct regulation" appears to be the most effective policy instrument for prompting the positive impact of environmental policies on innovation and intangible performance while economic instruments do negatively affect business performance. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. Consideration of environmental externality costs in electric utility resource selections and regulation

    International Nuclear Information System (INIS)

    Ottinger, R.L.

    1990-01-01

    A surprising number of state electric utility regulatory commissions (half) have started to require consideration of environmental externality costs in utility planning and resource selection. The principal rationale for doing so is that electric utility operations impose very real and large damages to human health and the environment which are not taken into account by traditional utility least cost planning, resource selection procedures, or by government pollution regulation. These failures effectively value the residual environmental costs to society of utility operations at zero. The likely future prospect for more stringent governmental pollution regulation renders imprudent the selection of resources without taking environmental externality costs into consideration. Most regulatory commissions requiring environmental externality consideration have left it to the utilities to compute the societal costs, although a few have either set those costs themselves or used a proxy adder to polluting resource costs (or bonus for non-polluting resources). These commissions have used control or pollution mitigation costs, rather than societal damage costs, in their regulatory computations. This paper recommends that damage costs be used where adequate studies exist to permit quantification, discusses the methodologies for their measurement, and describes the means that have been and might be used for their incorporation

  2. The innovation inducement impact of environmental regulations on maritime transport

    DEFF Research Database (Denmark)

    Makkonen, Teemu; Repka, Sari

    2016-01-01

    Maritime transport is facing wide-ranking challenges due to stricter environmental regulations. It has been positioned that these stricter environmental regulations will significantly hamper the competitiveness of the shipping industry and other export/import oriented industries. However, contras......Maritime transport is facing wide-ranking challenges due to stricter environmental regulations. It has been positioned that these stricter environmental regulations will significantly hamper the competitiveness of the shipping industry and other export/import oriented industries. However......), in general, and the economic impacts of environmental regulations (here Annex VI of the MARPOL Convention) as it applies to shipping in Northern Europe, in particular. According to the review, the literature is still inconclusive and lacks a clear consensus on the economic and innovation inducement impacts...... of environmental regulations on maritime transport. Therefore, the review concludes in suggestions for further studies on the use of marine scrubber systems as an illustrative case study example....

  3. Synthetic Peptides to Target Stringent Response-Controlled Virulence in a Pseudomonas aeruginosa Murine Cutaneous Infection Model

    Directory of Open Access Journals (Sweden)

    Daniel Pletzer

    2017-09-01

    Full Text Available Microorganisms continuously monitor their surroundings and adaptively respond to environmental cues. One way to cope with various stress-related situations is through the activation of the stringent stress response pathway. In Pseudomonas aeruginosa this pathway is controlled and coordinated by the activity of the RelA and SpoT enzymes that metabolize the small nucleotide secondary messenger molecule (pppGpp. Intracellular ppGpp concentrations are crucial in mediating adaptive responses and virulence. Targeting this cellular stress response has recently been the focus of an alternative approach to fight antibiotic resistant bacteria. Here, we examined the role of the stringent response in the virulence of P. aeruginosa PAO1 and the Liverpool epidemic strain LESB58. A ΔrelA/ΔspoT double mutant showed decreased cytotoxicity toward human epithelial cells, exhibited reduced hemolytic activity, and caused down-regulation of the expression of the alkaline protease aprA gene in stringent response mutants grown on blood agar plates. Promoter fusions of relA or spoT to a bioluminescence reporter gene revealed that both genes were expressed during the formation of cutaneous abscesses in mice. Intriguingly, virulence was attenuated in vivo by the ΔrelA/ΔspoT double mutant, but not the relA mutant nor the ΔrelA/ΔspoT complemented with either gene. Treatment of a cutaneous P. aeruginosa PAO1 infection with anti-biofilm peptides increased animal welfare, decreased dermonecrotic lesion sizes, and reduced bacterial numbers recovered from abscesses, resembling the phenotype of the ΔrelA/ΔspoT infection. It was previously demonstrated by our lab that ppGpp could be targeted by synthetic peptides; here we demonstrated that spoT promoter activity was suppressed during cutaneous abscess formation by treatment with peptides DJK-5 and 1018, and that a peptide-treated relA complemented stringent response double mutant strain exhibited reduced peptide

  4. Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Encoded mRNases

    DEFF Research Database (Denmark)

    Tian, Chengzhe; Roghanian, Mohammad; Jørgensen, Mikkel Girke

    2016-01-01

    Escherichia coli regulates its metabolism to adapt to changes in the environment, in particular to stressful downshifts in nutrient quality. Such shifts elicit the so-called stringent response coordinated by the alarmone guanosine tetra- and pentaphosphate [(p)ppGpp]. At sudden amino-acid (aa......RNase-encoding TA modules present in the wt strain. This observation suggested that toxins are part of the negative feedback to control the (p)ppGpp level during early stringent response. We built a ribosome trafficking model to evaluate the fold of increase in the RelA activity just after the onset of aa...... %. IMPORTANCE: The early stringent response elicited by amino-acid starvation is controlled by a sharp increase of the cellular (p)ppGpp level. Toxin-antitoxin encoded mRNases are activated by (p)ppGpp through enhanced degradation of antitoxins. The present work shows that this activation happens at a very...

  5. Essays on environmental regulations in electricity markets

    Science.gov (United States)

    Sun, Yanming

    Reducing the Greenhouse Gas pollution and promoting energy efficiency among consumers' energy use have been major public policy issues recently. Currently, both the United States and the European Union have set up explicit percentage requirements that require energy generators or consumers to undertake a certain percentage of their energy production or consumption from renewable sources. To achieve their renewable targets, the Tradable Green Certificates (TGC) system has been introduced in their electricity markets. Moreover, in order to promote energy conservation and achieve energy efficiency targets, price policies and price changes derived from environmental regulations have played a more important role in reducing electricity consumption. My research studies problems associated with these policy implementations. In Chapter 1, I analyze a competitive electricity market with two countries operated under a common TGC system. By using geometric illustrations, I compare the two countries' welfare when the renewable quota is chosen optimally under the common certificate market with three different situations. The policy recommendation is that when the value of damage parameter is sufficiently small, full integration with a TGC market is welfare superior to full integration of an all fossil-fuel based market with an optimal emissions standard. In Chapter 2, by analyzing a stylized theoretical model and numerical examples, I investigate the performance of the optimal renewables policy under full separation and full integration scenarios for two countries' electricity markets operated under TGC systems. In my third chapter, I look at residential electricity consumption responsiveness to increases of electricity price in the U.S. and the different effect of a price increase on electricity use for states of different income levels. My analysis reveals that raising the energy price in the short run will not give consumers much incentive to adjust their appliances and make

  6. Environmental Regulation and Food Safety: Studies of Protection ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Environmental Regulation and Food Safety: Studies of Protection and Protectionism. Book cover Environmental Regulation and Food Safety: Studies of Protection and Protectionism. Directeur(s) : Veena Jha. Maison(s) d'édition : Edward Elgar, IDRC. 1 janvier 2006. ISBN : 184542512X. 250 pages. e-ISBN : 155250185X.

  7. Phylogenetic analysis of proteins involved in the stringent response in plant cells.

    Science.gov (United States)

    Ito, Doshun; Ihara, Yuta; Nishihara, Hidenori; Masuda, Shinji

    2017-07-01

    The nucleotide (p)ppGpp is a second messenger that controls the stringent response in bacteria. The stringent response modifies expression of a large number of genes and metabolic processes and allows bacteria to survive under fluctuating environmental conditions. Recent genome sequencing analyses have revealed that genes responsible for the stringent response are also found in plants. These include (p)ppGpp synthases and hydrolases, RelA/SpoT homologs (RSHs), and the pppGpp-specific phosphatase GppA/Ppx. However, phylogenetic relationship between enzymes involved in bacterial and plant stringent responses is as yet generally unclear. Here, we investigated the origin and evolution of genes involved in the stringent response in plants. Phylogenetic analysis and primary structures of RSH homologs from different plant phyla (including Embryophyta, Charophyta, Chlorophyta, Rhodophyta and Glaucophyta) indicate that RSH gene families were introduced into plant cells by at least two independent lateral gene transfers from the bacterial Deinococcus-Thermus phylum and an unidentified bacterial phylum; alternatively, they were introduced into a proto-plant cell by a lateral gene transfer from the endosymbiotic cyanobacterium followed by gene loss of an ancestral RSH gene in the cyanobacterial linage. Phylogenetic analysis of gppA/ppx families indicated that plant gppA/ppx homologs form an individual cluster in the phylogenetic tree, and show a sister relationship with some bacterial gppA/ppx homologs. Although RSHs contain a plastidial transit peptide at the N terminus, GppA/Ppx homologs do not, suggesting that plant GppA/Ppx homologs function in the cytosol. These results reveal that a proto-plant cell obtained genes for the stringent response by lateral gene transfer events from different bacterial phyla and have utilized them to control metabolism in plastids and the cytosol.

  8. Review of Chinese Environmental Risk Assessment Regulations and Case Studies

    Science.gov (United States)

    Meng, Xiaojie; Zhang, Yan; Zhao, Yuchao; Lou, In Chio; Gao, Jixi

    2012-01-01

    Environmental risk assessment is an essential step in the development of solutions for pollution problems and new environmental regulations. An assessment system for environmental risks has been developed in China in recent decades. However, many of the Chinese technical guidelines, standards, and regulations were directly adapted from those of developed countries, and were not based on the Chinese environmental and socioeconomic context. Although existing environmental regulations for pollutants are usually obtained by extrapolations from high-dose toxicological data to low-dose scenarios using linear-non-threshold (LNT) models, toxicologists have argued that J-shaped or inverse J-shaped curves may dominate the dose–response relationships for environmental pollutants at low doses because low exposures stimulate biological protective mechanisms that are ineffective at higher doses. The costs of regulations based on LNT and J-shaped models could therefore be dramatically different. Since economic factors strongly affect the decision-making process, particularly for developing countries, it is time to strengthen basic research to provide more scientific support for Chinese environmental regulations. In this paper, we summarize current Chinese environmental policies and standards and the application of environmental risk assessment in China, and recommend a more scientific approach to the development of Chinese regulations. PMID:22740787

  9. Analyzing Environmental Policies for Chlorinated Solvents with a Model of Markets and Regulations

    Science.gov (United States)

    1991-01-01

    contributes to stratospheric ozone depletion. TCA is now being regulated more stringently, and one of the major substitute solvents contains d- limonene , which...ingredient of most cleaning formulations, d- limonene , has generated positive carcinogenicity results in male rats. -2- 500 TCE + S400 TCA 3 00 200 C 100 - 0...Regulators banned CFC propellants from aerosol products in December 1978. - 17 - OSlA. The Occupational Safety and Health Administration (OSHA) regulates

  10. ENVIRONMENTAL REGULATIONS ON AIR POLLUTION IN CHINA AND THEIR IMPACT ON INFANT MORTALITY

    OpenAIRE

    Tanaka, Shinsuke

    2012-01-01

    Developing countries rank highest in air pollution worldwide, yet regulations of such pollution are still rare in these countries, thereby whether, and to what extent, those regulations lead to health benefits remain an open question. Since 1995, the Chinese government has imposed stringent regulations on pollutant emissions from power plants, as one of the first regulatory attempts on a large scale in a developing country. Exploiting the variation in the regulatory status across time and spa...

  11. Competitiveness Implications of Environmental Regulations: Case Studies (1992- 1997)

    Science.gov (United States)

    This collection of reports is part of a series of case studies designed to examine Michael Porter’s hypothesis that innovative companies responding to environmental regulation can create competitive advantage through lower costs or higher sales.

  12. Environmental Regulations and Economic Activity: Influence on Market Structure

    OpenAIRE

    Daniel L. Millimet; Santanu Roy; Aditi Sengupta

    2009-01-01

    We survey recent developments in the theoretical and empirical literature on the economic effects of environmental regulation on various aspects of market structure including entry, exit, and size distribution of firms and market concentration.

  13. Environmental protection and traffic regulation in Slovenia

    Directory of Open Access Journals (Sweden)

    Aljaš Plevnik

    1998-01-01

    Full Text Available The article summarises the proposed chapter on traffic in the National programme for environmental protection. The main theme focuses on the suggested goals and measures to reach sustainable development in Slovenia. The goals and measures are derived from the current situation and traffic development trends and their influence on the environment, from international guidelines and the current Slovene policies.

  14. Environmental signaling and regulation of mushroom formation

    NARCIS (Netherlands)

    Pelkmans, J.F.

    2016-01-01

    Mushrooms are of great value as a food source. The Netherlands has a large share of the European white button mushroom (Agaricus bisporus) production. This market will increase in the future due to larger demand for high quality food with a growing world population. Environmental factors play a role

  15. Addressing environmental contamination through market regulations

    African Journals Online (AJOL)

    The existing legal frameworks in the United States (US) and the European Commission (EC) that regulate industrial chemicals represent divergent methods for controlling market entry, market restriction, and subsequent regulatory oversight when enforcement of these mechanisms fail. Contrary to the prevailing view that the ...

  16. The effect of increasingly stringent diagnostic criteria on sex ...

    African Journals Online (AJOL)

    Sex differences in premorbid function and symptomatology were examined as increasingly stringent criteria for schizophrenia were applied to 182 male and 139 female . psychotic patients. The male/female ratio rose from 1.6 among those meeting the CATEGO 'broad' criteria for schizophrenia to 3.7 among those satisfying ...

  17. Environmental regulations and emissions trading in China

    International Nuclear Information System (INIS)

    Chang, Y.-C.; Wang Nannan

    2010-01-01

    This paper begins with the international context concerning climate change and how China fits into this context. Concentration is then turning into the emissions control system in China including environmental planning, legislation, policy instruments and measures as well as institutional setting in China's environmental governance system. Special attentions also being paid to emissions control in China's power sector. It should be noted that the pollution discharge permit system in China only exists superficially in many places. Insufficient resources are applied to the implementation of the said permit system, which in turn means that the system is applied according to differing standards in different parts of the country. The findings of this paper suggested that emissions trading programmes are usually introduced alongside the existing policies. The power sector usually has numerous other policy objectives and therefore the design and implementation of emissions trading programmes in the sector will have to address concern about the compatibility of existing industry policies.

  18. Environmentally Friendly Concept in Spatial Regulation

    Directory of Open Access Journals (Sweden)

    T Taryono

    2004-01-01

    Full Text Available Spatial order of a region include purpose of structure and interrelatedness of spatial order which as a unity of development mechanism. Spatial order can’t be part from law basic that is UUD’45 and GBHN, in order to the management can be integrated and keep the environment. Spatial order also take note of physical factor and non physical factor. Physical factor consist of soil, water, flora, and fauna. Non physical factors consist of environment, social, economic, and soon. The principle of arrangement of spatial order in a region include national region, regional and local, and a region as an administrative baoundary, that is local government authority, like province, district, subdistrict, and village. The effort for spatial ordering of the environment, for example ordering resource, arrangement of allocation and location, arrangement of environmental aesthetic  and arrangement of environmental quality.

  19. Regulating Environmental Impacts of Mining in Norway

    OpenAIRE

    Fauchald, Ole Kristian

    2014-01-01

    The article examines how environmental concerns of mining can be addressed under the Minerals Act, the Planning and Building Act and the Pollution Control Act, as well as potential effects of the principles set out in the Nature Diversity Act. One objective of the article is to contribute to a discussion of distribution of power and responsibility for management of ecosystem services among central public authorities, local communities and market actors. The regulatory and administrative re...

  20. Study on effects of environmental regulation on competitiveness

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Man Ok; Lim, Hyun Jeong [Korea Environment Institute, Seoul (Korea)

    1999-12-01

    For Korea, the claim that the enhancement of environmental regulation is worsening the international competitiveness of the business is dominant. However, it is too early to reestablish a relationship between environmental regulation and competitiveness with the above new aspect. In fact, the economic development, which is brought a quantitative growth, and the maintenance of environmental quality, which is brought a qualitative growth, are very important on decision making in economic and social policy. In this study, it represents the results of existing positive studies on the relationship between the enhancement of environmental regulation, trade and productivity. Moreover, the objective of this study is on applying it based on the data of Korea. 86 refs., 13 figs., 35 tabs.

  1. [Environmental damage assessment: international regulations and revelation to China].

    Science.gov (United States)

    Zhang, Hong-zhen; Cao, Dong; Yu, Fang; Wang, Jin-nan; Qi, Ji; Jia, Qian; Zhang, Tian-zhu; Luo, Yong-ming

    2013-05-01

    As the whole society gradually realizes the scarcity of nature resources and environmental value, countries all over the world have evolved and improved the system of environmental damage assessment through the practices of pollution prevention and ecological environmental protection. On one hand, in the research prospective, the practices of environmental damage assessment brought new challenges to environmental law, environmental economics, environmental science, environmental engineering, etc. On the other hand, they constantly promoted and developed relevant laws and regulations, techniques, working mechanism, and guidelines on procedure in practice. On the hasis of comparison and analysis of international practices and experiences from US, EU, and Japan, etc., this article identified relevant concepts, content, and scope of environmental damage assessment, and presented its scientific positioning and development direction. At present, both theory and practice of environmental damage assessment in China are in their infancy period. Considering current environmental situation and socioeconomic development features of China, learning international practices and experiences and raising the orientation of environmental damage assessment have great meaning in exploring the suitable environmental damage assessment system.

  2. Environmental regulation of a power investment in an international market

    International Nuclear Information System (INIS)

    Vennemo, H.; Halseth, A.

    2001-01-01

    We examine the optimal environmental regulation of three Norwegian power projects: energy conservation, a natural gas fired CCGT and a new hydro project. All projects reduce emissions elsewhere in the Nordic region, and the environmental costs of these emissions are not, in general, fully reflected in market prices. We develop a theory of second best optimal regulation for this case. The optimal regulation is found to deviate substantially from a purely domestic regulation. For instance, we find it optimal to grant a substantial credit to energy conservation. The credit is sensitive to the value of reduced CO 2 emissions and whether the current Norwegian end user tax should be interpreted as an environmental or a fiscal tax

  3. Extended Producer Responsibility and corporate performance: Effects of environmental regulation and environmental strategy.

    Science.gov (United States)

    Peng, Benhong; Tu, Yu; Elahi, Ehsan; Wei, Guo

    2018-04-18

    While contemporary manufacturing technologies stimulate the industrial revolution and promote the rapidly changing global economy, it has caused enormous environmental negative externalities and managing the industrial waste remains a primary challenge, especially for fast developing countries such as China. Though existing studies explored the influence of Extended Producer Responsibility (EPR) legislations on environmental externalities, only fewer researches aimed at policy issues. Particularly, the relationship among environmental regulations, environmental strategies and corporate performance in the EPR system has not been deeply investigated. To fill this gap, this research will focus to assess the economic aspect and environmental performance associated with the environmental regulations and strategies. For this purpose, 208 cross-sectional questionnaires were administered with three major high-pollution industries, electrical and electronic, automobile and lead-acid storage battery industries. To accomplish this study objective, we employ a two-step approach: firstly, validity tests for environmental regulation and environmental strategy along with the corporate performance are performed by the factor analysis method, and secondly, the structural equation model is utilized to test the study hypotheses. Results reveal that command and control (CAC) and market-based incentive (MBI) environmental regulations are significantly impacting on the reactive environmental strategy (RES); however, the proactive environmental strategy (PES) only has a significant relationship with MBI regulation. On the other hand, RES only has a significant relationship with the enterprises economics performance, while PES has a statistically significant relationship with both economic and environmental performance of enterprises. Therefore, the central government and its local offices are strongly urged to coordinate the industries by making, implementing and monitoring necessary and

  4. Is environmental impact assessment regulation a 'burden' to private firms?

    International Nuclear Information System (INIS)

    Annandale, David; Taplin, Ross

    2003-01-01

    The impact of environmental regulation on macroeconomic performance has been studied in some depth over the last 15 years. Similarly, impact on profit performance, investment intention and location decisions of firms has also been studied, although in less depth. There has been less academic interest, however, in the impact that environmental regulation has on the strategic objectives of companies. This article reports on a research project that focused on the impact that environmental approvals regulation (predominantly environmental impact assessment, EIA) has on proposed new development in the international mining sector. Based on a large and externally valid survey of senior mining company executives in Australia and Canada in the late 1990s, the research indicated that a significant majority of firms consider the environmental approvals process to be an important determinant of investment strategy. An initial reaction to these figures might suggest that the majority of respondents believe the environmental approvals process to be a negative influence. However, further questioning indicated that only a small proportion of companies in both countries thought of the environmental approvals process as an impediment to development. Instead, it is clear that most firms see EIA as a catalyst for integrating environmental design into the early planning of a project, thereby alleviating the need to spend money on overcoming environmental problems once a poorly designed project has been commissioned. The somewhat surprising conclusion that companies see environmental approvals regulation as important, but as an encouragement to development rather than as an impediment, goes against much previous industry and academic comment and, at least in relation to the mining sector, refutes the idea that EIA is ''burdensome''

  5. Institutionalizing environmental protection through self-regulation: the case of environmental standards adoption in Lithuania.

    Science.gov (United States)

    Bileisis, Mantas; Misiune, Ieva

    2017-04-01

    The impacts of human activity in the environment have a global dimension, but there are no effective global governance instruments to enforce environmental standards. At the same time, many national governments lack incentives to pursue strict environmental policies. In this context, self-regulation is seen as an alternative venue to address environmental challenges. This work aims to identify factors that influence companies to engage in environmental self-regulation? For this aim in March 2015 a survey of 482 companies was conducted. The target group were companies operating in Lithuania that hold ISO14001 certificates - one of the most prolific instruments for self-regulation. The questionnaire was designed to test assumptions developed in new institutionalist literature which claim that common practices can emerge through isomorphism.- The results showed that the main motive for environmental self-regulation is the desire to improve company image, rather than protecting the environment per se. Another important finding was that the main source of pressure to adopt self-regulation was based less on the perceived demands but the customers. Rather the driver for the adoption was a feeling of a need no to fall behind industry leaders. Thus, normative isomorphism is the main mechanism through which environmental self-regulation proliferates. We claim for a rapid proliferation of environmental self-regulation perceived industry leaders need to be identified and they need to be persuaded that environmental standards are key for the development of the industry. However, this also raises questions of sustainability. Few industries have long standing leaders, and through successful investment and technological development new actors can arise and this may risk stalling or even reversing self-regulation.

  6. Environmental regulations handbook for enhanced oil recovery. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, T.D.

    1980-08-01

    A guide to environmental laws and regulations which have special significance for enhanced oil recovery (EOR) is presented. The Clean Air Act, the Clean Water Act, the Safe Drinking Water Act, Resource Conservation and Recovery Act, federal regulations, and state regulations are discussed. This handbook has been designed as a planning tool and a convenient reference source. The 16 states included comprise the major oil-producing states in various regions of the state. The major topics covered are: general guidelines for complying with environmental laws and regulations; air pollution control; water pollution control; protecting drinking water: underground injection control; hazardous waste management; and federal laws affecting siting or operation of EOR facilities. (DMC)

  7. Environmental Regulation and Food Safety: Studies of Protection ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2006-01-01

    Jan 1, 2006 ... ... standard setting, not simply the technical process, North–South issues, and the political economy of organic food markets. Environmental Regulation and Food Safety will appeal to policymakers and NGOs, researchers and scholars of international and development economics, as well industry strategists.

  8. Mechanisms for the environmental regulation of gene expression ...

    Indian Academy of Sciences (India)

    Unknown

    The environment can play a significant role in the production of phenotypes. However, the ... phenotype production by the environment should be considered a normal component of development and devel- opmental biology. .... Hormonal regulation mediates the environmentally controlled pigmentation of Araschnia. In the.

  9. Environmental Regulation and Food Safety: Studies of Protection ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 janv. 2006 ... Environmental Regulation and Food Safety intéressera les artisans des politiques et les ONG , les chercheurs et les spécialistes de l'économie ... This funding will help strengthen the Science, Technology and Innovation Policy Research Organization's (STIPRO) role as a credible public policy institution in ...

  10. Strategic choices in the environmental debate: Environmental regulation and self-regulation

    DEFF Research Database (Denmark)

    Ulhøi, John Parm

    Den aktuelle miljødebat, der føres i litteraturen, kan give direkte anledning til den uheldige opfattelse, at det overvejende er et spørgsmål om miljøregulering eller indirekte regulering baseret på markedskræfterne. Dette er i modstrid med den kendsgerning, at der findes mange kombinationer i...

  11. Environmental regulation incidences towards international oligopolies: pollution taxes vs emission permits

    OpenAIRE

    PRATLONG Florent

    2005-01-01

    The purpose of this paper is to analyze whether the choice between two instruments of environmental policy (pollution taxes vs emission permits) affects the market shares in the presence of imperfectly competitive product markets. We consider two countries, referred to as the Domestic country and the Foreign country, agreeing on an equally stringent exogenous ceiling on pollution. These countries are also suppliers on the international markets of two commodities produced by two separate secto...

  12. Effects of new environmental regulations on coal-fired generation

    International Nuclear Information System (INIS)

    LaCount, R.

    1999-01-01

    As restructuring of the electricity industry places downward pressure on power production costs, new environmental regulations are having the opposite effect. Although power plants may be subject to a variety of environmental regulations over the next ten years including reductions in mercury, toxics, and carbon dioxide, new regulations for sulfur dioxide (SO2) and nitrogen oxides (NOX) are poised to impact the electricity industry in the very short term. The cost for coal-fired power plants to comply with these new regulations has the potential to alter their competitive position. January 1, 2000 marks the beginning of Phase II for the Environmental Protection Agency's SO2 allowance market. Starting in January, all coal and oil plants above 25 MW will be required to comply with the federal SO2 provisions. Regulatory deadlines for NOX are also fast approaching; though the ultimate requirements are still subject to change. On May 1, 1999, a NOX allowance market began for states within the Northeast Ozone Transport Commission (OTC). A second phase of this program is scheduled to begin in 2003 that will lower the overall cap for allowable NOX emissions in the participating states. EPA is also working to expand the reach of regional NOX reductions in 2003 through its NOX SIP call. This program, which is currently subject to litigation, would require NOX reductions in 14 states outside of the OTC. A new study by Resource Data International (RDI), Coal-Fired Generation in Competitive Power Markets, assessed the potential impact that the new SO2 and NOX regulations may have on the competitiveness of coal-fired generation. Overall, the study shows that coal-fired generation will continue to grow despite significant environmental costs and competition from natural gas-fired units. The new environmental regulations have the effect of increasing the dispatch cost of coal-fired units from $0.65/MWh on average in the WSCC to $4.14/MWh on average in the MAAC region. The addition

  13. Review of orders and regulations requiring environmental protection

    International Nuclear Information System (INIS)

    Kelly, E.; Cunningham, R.; Michael, D.

    1996-01-01

    With the increased awareness of and interest in potential ecological risks associated with past, current, and future Department of Energy (DOE) activities, DOE's Defense Programs (DP) Office of Technical and Environmental Support sponsored a study to (1) evaluate the effectiveness of the current compliance-driven environmental protection and assessment efforts relative to ecological concerns; (2) explore the need for a more focused, integrated approach to address ecological impacts; and (3) identify the requirements for an integrated approach. The study explored four questions. (a) Which federal regulations and DOE orders either explicitly require ecological assessments or implicitly require them through environmental protection language? (b) What currently is being done at selected DOE facilities to implement these regulations and orders? (c) What are private sector industries doing in terms of ecological risk assessments and how do industry approaches and issues compare with those of DOE? (d) What, if anything, in addition to current efforts is needed to ensure the protection of ecological resources associated with DOE facilities, to support defensible decision making, and to improve efficiency? The results of this study are presented in a report titled open-quotes Integrated, Comprehensive Ecological Impact Assessments In Support of Department of Energy Decision Makingclose quotes. This report is a companion document to that report. This report provides a more detailed discussion of the document reviews of the relevant environmental protection regulations and current and pending DOE orders. The main goal of the document reviews was to understand existing requirements for ecological data collection and impact assessments

  14. Environmental regulation of exploration and mining operations in Asian countries

    International Nuclear Information System (INIS)

    Otto, J.; Naito, Koh; Pring, G.

    1999-01-01

    This paper offers a new perspective on the environmental laws in Asian nations affecting the exploration, mining, and reclamation activities of the mineral resource industry: the perspective of the senior government officials in those countries, whose job is to enforce these new environmental laws. The article presents the results of a 1998 survey of national environmental officials in Asia conducted by the Colorado School of Mines and the Metal Mining Agency of Japan. Officials in 10 diverse countries - Cambodia, China, Indonesia, Lao PDR, Malaysia, Myanmar, Mongolia, Philippines, Thailand and Vietnam - responded to a detailed questionnaire covering applicable laws, agencies, protected areas, covered mineral activities, financial assurance, environmental impact assessment, public involvement, environmental standards, permit and reclamation requirements. The survey confirms that Asian nations are part of the global trend towards national government regulatory structures that balance mineral development objectives with environmental considerations. The survey also shows developing regulatory systems (some embryonic, some more mature) utilizing a combination of mining and environmental acts, and often an 'insider' perspective of the national officials administering the laws. While that perspective is not without its biases (not least the rigor of enforcement), it may nevertheless be of use in company planning. The emerging regulatory picture contradicts the conventional notion that it is the 'lower' level of regulation in Asia that is attracting foreign direct investment in mining. (author)

  15. How Does Environmental Regulation Affect Industrial Transformation? A Study Based on the Methodology of Policy Simulation

    Directory of Open Access Journals (Sweden)

    Wei Liu

    2016-01-01

    Full Text Available The difference of factor input structure determines different response to environmental regulation. This paper constructs a theoretical model including environmental regulation, factor input structure, and industrial transformation and conducts a policy simulation based on the difference of influencing mechanism of environmental regulation considering industrial heterogeneity. The findings show that the impact of environmental regulation on industrial transformation presents comparison of distortion effect of resource allocation and technology effect. Environmental regulation will promote industrial transformation when technology effect of environmental regulation is stronger than distortion effect of resource allocation. Particularly, command-control environmental regulation has a significant incentive effect and spillover effect of technological innovation on cleaning industries, but these effects do not exist in pollution-intensive industries. Command-control environmental regulation promotes industrial transformation. The result of simulation showed that environmental regulation of market incentives is similar to that of command-control.

  16. Flight Hardware Packaging Design for Stringent EMC Radiated Emission Requirements

    Science.gov (United States)

    Lortz, Charlene L.; Huang, Chi-Chien N.; Ravich, Joshua A.; Steiner, Carl N.

    2013-01-01

    This packaging design approach can help heritage hardware meet a flight project's stringent EMC radiated emissions requirement. The approach requires only minor modifications to a hardware's chassis and mainly concentrates on its connector interfaces. The solution is to raise the surface area where the connector is mounted by a few millimeters using a pedestal, and then wrapping with conductive tape from the cable backshell down to the surface-mounted connector. This design approach has been applied to JPL flight project subsystems. The EMC radiated emissions requirements for flight projects can vary from benign to mission critical. If the project's EMC requirements are stringent, the best approach to meet EMC requirements would be to design an EMC control program for the project early on and implement EMC design techniques starting with the circuit board layout. This is the ideal scenario for hardware that is built from scratch. Implementation of EMC radiated emissions mitigation techniques can mature as the design progresses, with minimal impact to the design cycle. The real challenge exists for hardware that is planned to be flown following a built-to-print approach, in which heritage hardware from a past project with a different set of requirements is expected to perform satisfactorily for a new project. With acceptance of heritage, the design would already be established (circuit board layout and components have already been pre-determined), and hence any radiated emissions mitigation techniques would only be applicable at the packaging level. The key is to take a heritage design with its known radiated emissions spectrum and repackage, or modify its chassis design so that it would have a better chance of meeting the new project s radiated emissions requirements.

  17. A study on the relationship of environmental regulations and economic performances

    Science.gov (United States)

    Nisha, Jia; Chen, Shen

    2017-11-01

    This paper analyzes the mechanism transmission of environmental regulation affecting on economic performance from a new perspective. It shows that environmental regulations affect country’s economic performance through direct transmission and indirect transmission. Direct transmission means that environmental regulations affect economic performance from influencing corporation’s cost and revenue, and indirect transmission is that environmental regulations affect economic performance through leading to the increased effort of corporations in improving the quality of environment and building the image of fulfilling environmental responsibility.

  18. Comparison of urine iodine/creatinine ratio between patients following stringent and less stringent low iodine diet for radioiodine remnant ablation of thyroid cancer

    International Nuclear Information System (INIS)

    Roh, Jee Ho; Kim, Byung Il; Ha, Ji Su; Chang, Sei Joong; Shin, Hye Young; Choi, Joon Hyuk; Kim, Do Min; Kim, Chong Soon

    2006-01-01

    A low iodine diet (LID) for 1 ∼ 2 weeks is recommended for patients who undergoing radioiodine remnant ablation. However, the LID educations for patients are different among centers because there is no concrete recommendation for protocol of LID. In this investigation, we compared two representative types of LID protocols performed in several centers in Korea using urine iodine to creatinine tatio (urine I/Cr). From 2006, April to June, patients referred to our center for radioiodine remnant ablation of thyroid cancer from several local hospitals which had different LID protocols were included. We divided into two groups, stringent LID for 1 week and less stringent LID for 2 weeks, then measured their urine I/Cr ratio with spot urine when patients were admitted to the hospital. Total 27 patients were included in this investigation (M:F = 1:26; 13 in one-week stringent LID; 14 in two-week less stringent LID). Average of urine I/Cr ratio was 127.87 ± 78.52 μ g/g in stringent LID for 1 week, and 289.75 ± 188.24 μ g/g in less stringent LID for 2 weeks. It was significantly lower in stringent LID for 1 week group (ρ = 0.008). The number of patients whose urine I/Cr ratios were below 100 μ g/g was 6 of 13 in stringent LID for 1 week group, and 3 of 14 in less stringent LID for 2 weeks group. Stringent LID for 1 week resulted in better urinary I/Cr ratio in our investigation compared with the other protocol. However it still resulted in plenty of inadequate range of I/Cr ratio, so more stringent protocol such as stringent LID for 2 weeks is expected more desirable

  19. Economic growth and energy regulation in the environmental Kuznets curve.

    Science.gov (United States)

    Lorente, Daniel Balsalobre; Álvarez-Herranz, Agustín

    2016-08-01

    This study establishes the existence of a pattern of behavior, between economic growth and environmental degradation, consistent with the environmental Kuznets curve (EKC) hypothesis for 17 Organization for Economic Cooperation and Development (OECD) countries between 1990 and 2012. Based on this EKC pattern, it shows that energy regulation measures help reduce per capita greenhouse gas (GHG) emissions. To validate this hypothesis, we also add the explanatory variables: renewable energy promotion, energy innovation processes, and the suppression effect of income level on the contribution of renewable energy sources to total energy consumption. It aims to be a tool for decision-making regarding energy policy. This paper provides a two-stage econometric analysis of instrumental variables with the aim of correcting the existence of endogeneity in the variable GDP per capita, verifying that the instrumental variables used in this research are appropriate for our aim. To this end, it first makes a methodological contribution before incorporating additional variables associated with environmental air pollution into the EKC hypothesis and showing how they positively affect the explanation of the correction in the GHG emission levels. This study concludes that air pollution will not disappear on its own as economic growth increases. Therefore, it is necessary to promote energy regulation measures to reduce environmental pollution.

  20. Incorporating Environmental Regulation and Litigation in Earth Science Curriculum

    Science.gov (United States)

    Flegal, A. R.

    2004-12-01

    Fundamental knowledge of geological processes is not only needed for effective environmental regulation and litigation, but Earth Science students find that relevance motivating in their studies of those processes. Crustal abundance and redox reactions suddenly become personally meaningful when they are used to account for the presence of high levels of carcinogenic Cr(VI) in the students' drinking water. Similarly, epithermal mercury deposits and the element's speciation gain new importance when they are related to the warning signs on the consumption of fish that the students catch and eat. And even those students that are not motivated by these, and many other, applications of geology find solace in learning that anthropogenic perturbations of the global lead cycle may partially account for their short attention span, lack of interest, and inability to learn the material. Consequently, a number of courses in environmental toxicology and ground water contamination have been developed that are based on (1) case studies in environmental regulation and litigation and (2) active student participation as "expert witnesses" opining on the scientific basis of environmental decisions.

  1. Environmental effects on hormonal regulation of testicular descent

    DEFF Research Database (Denmark)

    Toppari, J; Virtanen, H E; Skakkebaek, N E

    2006-01-01

    Regulation of testicular descent is hormonally regulated, but the reasons for maldescent remain unknown in most cases. The main regulatory hormones are Leydig cell-derived testosterone and insulin-like factor 3 (INSL3). Luteinizing hormone (LH) stimulates the secretion of these hormones, but the ...... hypothesize that an exposure to a mixture of chemicals with anti-androgenic or estrogenic properties (either their own activity or their effect on androgen-estrogen ratio) may be involved in cryptorchidism....... cause some cases of undescended testis. Similarly, androgen insensitivity or androgen deficiency can cause cryptorchidism. Estrogens have been shown to down regulate INSL3 and thereby cause maldescent. Thus, a reduced androgen-estrogen ratio may disturb testicular descent. Environmental effects changing...

  2. The Stringent Response Induced by Phosphate Limitation Promotes Purine Salvage in Agrobacterium fabrum.

    Science.gov (United States)

    Sivapragasam, Smitha; Deochand, Dinesh K; Meariman, Jacob K; Grove, Anne

    2017-10-31

    Agrobacterium fabrum induces tumor growth in susceptible plant species. The upregulation of virulence genes that occurs when the bacterium senses plant-derived compounds is enhanced by acidic pH and limiting inorganic phosphate. Nutrient starvation may also trigger the stringent response, and purine salvage is among the pathways expected to be favored under such conditions. We show here that phosphate limitation induces the stringent response, as evidenced by production of (p)ppGpp, and that the xdhCSML operon encoding the purine salvage enzyme xanthine dehydrogenase is upregulated ∼15-fold. The xdhCSML operon is under control of the TetR family transcription factor XdhR; direct binding of ppGpp to XdhR attenuates DNA binding, and the enhanced xdhCSML expression correlates with increased cellular levels of (p)ppGpp. Xanthine dehydrogenase may also divert purines away from salvage pathways to form urate, the ligand for the transcription factor PecS, which in the plant pathogen Dickeya dadantii is a key regulator of virulence gene expression. However, urate levels remain low under conditions that produce increased levels of xdhCSML expression, and neither acidic pH nor limiting phosphate results in induction of genes under control of PecS. Instead, expression of such genes is induced only by externally supplemented urate. Taken together, our data indicate that purine salvage is favored during the stringent response induced by phosphate starvation, suggesting that control of this pathway may constitute a novel approach to modulating virulence. Because bacterial purine catabolism appears to be unaffected, as evidenced by the absence of urate accumulation, we further propose that the PecS regulon is induced by only host-derived urate.

  3. Environmental policies and regulations on the electricity market in EC

    International Nuclear Information System (INIS)

    Boucher, J.

    1990-01-01

    The use of natural resources like ground and water, the emissions of noxious gases and particles, the thermal rejections, the production of waste and the noise are the main environmental impacts associated with the production of electricity. Emission regulations and standards have been selected so far by the European Community (EC) and the different Member States to deal with the abatement problem. They simply consist in defining some ceilings or regulations for the different types of noxious gases and particles which are emitted by power plants and forcing the power generation companies to comply with these norms within some pre-determined time period. They can also take the form of a general constraint on the sulfur content of the fuel, for example. Tables of emission limits for various gases from existing and new plants are presented. 3 figs., 8 tabs

  4. Study on environmental results improvement plan through flexible industrial environmental regulation system

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Hyun Joo; Chang, Kee Bok; Lee, Young Soon [Korea Environment Institute, Seoul (Korea)

    1999-12-01

    As the economic environment has been changed to the direction of decentralization and diversification, there shows various changes in the area and method of market intervention by the government. In the environmental sector, it has been discussed to extend its use of economic incentive coming out of an existing direct regulation policy. Recently the importance on the new forms of government role such as voluntary agreements and information opening have been emphasized. Although the existing direct regulation policy has an advantage of visible and direct effect, it blocked the chance to explore technological and economical alternatives toward environmental problems by business sector. Therefore it is recognized that there is a fundamental limit on inducing the efficient pollution resisting activities from the business sector. Therefore this study analyzed and recommended theoretical characteristics on mechanism that a voluntary approach can bring appropriate results on policy objectives. 98 refs. 7 figs., 47 tabs.

  5. Environmental Policy with Collective Waste Disposal

    OpenAIRE

    Hamilton, Stephen F.; Sproul, Thomas W.; Sunding, David; Zilberman, David

    2013-01-01

    Centralized collection and disposal is an integral component of waste management strategies for many solid and liquid wastes, and carbon capture and storage is currently being considered for gaseous waste. In this paper we show how collective waste disposal systems introduce essential changes in the design of optimal environmental policy. Absent collective disposal, an optimal environmental policy imposes relatively stringent regulations on polluters in regions where local environmental damag...

  6. Heterogeneity of the environmental regulation of industrial wastewater: European wineries.

    Science.gov (United States)

    Román-Sánchez, Isabel M; Aznar-Sánchez, José A; Belmonte-Ureña, Luis J

    2015-01-01

    The European legislation of the pollution of industrial wastewater shows a high degree of heterogeneity. This fact implies that there is a market failure with relevant consequences. Within the European Union, each Member State performs a specific transposition of the Water Framework Directive 2000/60. The member states introduce different sanitation fees to correct water pollution. In this paper, the case of the European wine industry is analyzed. It studies the sanitation fees of the five major wine producing countries: France, Italy, Spain, Germany and Portugal. Results show significant differences among the wastewater fees and the study reveals how such heterogeneity leads to relevant market distortions. The research concludes that more homogeneous environmental regulation would promote more sustainable wine production processes with more efficient water management and purification systems, as well as the introduction of cutting edge technologies.

  7. Molecular targets of epigenetic regulation and effectors of environmental influences

    International Nuclear Information System (INIS)

    Choudhuri, Supratim; Cui Yue; Klaassen, Curtis D.

    2010-01-01

    The true understanding of what we currently define as epigenetics evolved over time as our knowledge on DNA methylation and chromatin modifications and their effects on gene expression increased. The current explosion of research on epigenetics and the increasing documentation of the effects of various environmental factors on DNA methylation, chromatin modification, as well as on the expression of small non-coding RNAs (ncRNAs) have expanded the scope of research on the etiology of various diseases including cancer. The current review briefly discusses the molecular mechanisms of epigenetic regulation and expands the discussion with examples on the role of environment, such as the immediate environment during development, in inducing epigenetic changes and modulating gene expression.

  8. Compliance with Environmental Regulations through Complex Geo-Event Processing

    Directory of Open Access Journals (Sweden)

    Federico Herrera

    2017-11-01

    Full Text Available In a context of e-government, there are usually regulatory compliance requirements that support systems must monitor, control and enforce. These requirements may come from environmental laws and regulations that aim to protect the natural environment and mitigate the effects of pollution on human health and ecosystems. Monitoring compliance with these requirements involves processing a large volume of data from different sources, which is a major challenge. This volume is also increased with data coming from autonomous sensors (e.g. reporting carbon emission in protected areas and from citizens providing information (e.g. illegal dumping in a voluntary way. Complex Event Processing (CEP technologies allow processing large amount of event data and detecting patterns from them. However, they do not provide native support for the geographic dimension of events which is essential for monitoring requirements which apply to specific geographic areas. This paper proposes a geospatial extension for CEP that allows monitoring environmental requirements considering the geographic location of the processed data. We extend an existing platform-independent, model-driven approach for CEP adding the geographic location to events and specifying patterns using geographic operators. The use and technical feasibility of the proposal is shown through the development of a case study and the implementation of a prototype.

  9. Some problems of risk balancing for regulating environmental hazards

    International Nuclear Information System (INIS)

    Gilbert, T.L.

    1984-01-01

    Rational regulation of environmental hazards may be based on the implicit underlying principles that government actions should enhance the average quality of life for those governed and maintain some degree of equity in the distribution of benefits, costs, and risks. Issues arising from these principles have practical implications for risk management policy in general and for the development and application of radiological protection criteria in particular. One of the issues is the appropriate distribution of expenditures for regulating different risks. The total resources available for risk regulation are finite; hence, minimizing the total risk subject to this constraint is an appropriate strategy for optimum risk management. Using a simple model, it is shown that this strategy leads to a distribution of expenditures between different risks such that a greater fraction is allocated to a risk with a higher cost of mitigation or control but the allocation is limited in such a manner that the fractional contribution of that risk to the total risk is also higher. The effect of deviating from this strategy is examined. It is shown that reducing a single risk of concern below the optimum value by a factor 1/F can increase the total risk by about F times the risk of concern. Taking into account the large uncertainties in risk assessment for establishing radiological protection criteria, it is argued that an optimum strategy for remedial action should (1) set basic risk limits as high as reasonable; (2) use realistic, case-specific data and analyses in deriving allowable residual contamination levels from basic risk limits; and (3) implement a policy of reducing residual contamination to levels that are as low as reasonably achievable (ALARA) within the constraints imposed by optimum resource allocation. 10 references

  10. Problems of risk balancing for regulating environmental hazards

    International Nuclear Information System (INIS)

    Gilbert, T.L.

    1985-01-01

    Rational regulation of environmental hazards may be based on the implicit underlying principles that government actions should enhance the average quality of life for those governed and maintain some degree of equity in the distribution of benefits, costs, and risks. Issues arising from these principles have practical implications for risk management policy in general and for the development and application of radiological protection criteria in particular. One of the issues is the appropriate distribution of expenditures for regulating different risks. The total resources available for risk regulation are finite; hence, minimizing the total risk subject to this constraint is an appropriate strategy for optimum risk management. Using a simple model, it is shown that this strategy leads to a distribution of expenditures between different risks such that a greater fraction is allocated to a risk with a higher cost of mitigation or control but the allocation is limited in such a manner that the fractional contribution of that risk to the total risk is also higher. The effect of deviating from this strategy is examined. It is shown that reducing a single risk of concern below the optimum value by a factor 1/F can increase the total risk by about F times the risk of concern. Taking into account the large uncertainties in risk assessment for establishing radiological protection criteria, it is argued that an optimum strategy for remedial action should (1) set basic risk limits as high as reasonable; (2) use realistic, case-specific data and analyses in deriving allowable residual contamination levels from basic risk limits; and (3) implement a policy of reducing residual contamination to levels that are as low as reasonably achievable (ALARA) within the constraints imposed by optimum resource allocation. 10 references, 1 figure

  11. Environmental contaminants and microRNA regulation: Transcription factors as regulators of toxicant-altered microRNA expression

    International Nuclear Information System (INIS)

    Sollome, James; Martin, Elizabeth; Sethupathy, Praveen; Fry, Rebecca C.

    2016-01-01

    MicroRNAs (miRNAs) regulate gene expression by binding mRNA and inhibiting translation and/or inducing degradation of the associated transcripts. Expression levels of miRNAs have been shown to be altered in response to environmental toxicants, thus impacting cellular function and influencing disease risk. Transcription factors (TFs) are known to be altered in response to environmental toxicants and play a critical role in the regulation of miRNA expression. To date, environmentally-responsive TFs that are important for regulating miRNAs remain understudied. In a state-of-the-art analysis, we utilized an in silico bioinformatic approach to characterize potential transcriptional regulators of environmentally-responsive miRNAs. Using the miRStart database, genomic sequences of promoter regions for all available human miRNAs (n = 847) were identified and promoter regions were defined as − 1000/+500 base pairs from the transcription start site. Subsequently, the promoter region sequences of environmentally-responsive miRNAs (n = 128) were analyzed using enrichment analysis to determine overrepresented TF binding sites (TFBS). While most (56/73) TFs differed across environmental contaminants, a set of 17 TFs was enriched for promoter binding among miRNAs responsive to numerous environmental contaminants. Of these, one TF was common to miRNAs altered by the majority of environmental contaminants, namely SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 3 (SMARCA3). These identified TFs represent candidate common transcriptional regulators of miRNAs perturbed by environmental toxicants. - Highlights: • Transcription factors that regulate environmentally-modulated miRNA expression are understudied • Transcription factor binding sites (TFBS) located within DNA promoter regions of miRNAs were identified. • Specific transcription factors may serve as master regulators of environmentally-mediated microRNA expression

  12. Environmental Strategies of Affect Regulation and Their Associations With Subjective Well-Being

    Directory of Open Access Journals (Sweden)

    Kalevi M. Korpela

    2018-04-01

    Full Text Available Environmental strategies of affect regulation refer to the use of natural and urban socio-physical settings in the service of regulation. We investigated the perceived use and efficacy of environmental strategies for regulation of general affect and sadness, considering them in relation to other affect regulation strategies and to subjective well-being. Participants from Australia, Finland, Germany, Great Britain, Italy, India, the Netherlands, Portugal, and Sweden (N = 507 evaluated the frequency of use and perceived efficacy of affect regulation strategies using a modified version of the Measure of Affect Regulation Styles (MARS. The internet survey also included the Satisfaction with Life Scale (SWLS, emotional well-being items from the RAND 36-Item Health Survey, and a single-item measure of perceived general health. Environmental regulation formed a separate factor of affect regulation in the exploratory structural equation models (ESEM. Although no relations of environmental strategies with emotional well-being were found, both the perceived frequency of use and efficacy of environmental strategies were positively related to perceived health. Moreover, the perceived efficacy of environmental strategies was positively related to life satisfaction in regulating sadness. The results encourage more explicit treatment of environmental strategies in research on affect regulation.

  13. 10 CFR 20.2007 - Compliance with environmental and health protection regulations.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Compliance with environmental and health protection regulations. 20.2007 Section 20.2007 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2007 Compliance with environmental and health protection regulations. Nothing...

  14. Drivers and drawbacks: regulation and environmental risk management systems

    OpenAIRE

    Marius Aalders

    2002-01-01

    In the literature on environmental risk management in firms, it is often proposed that environmental performance and innovation are driven primarily by external forces, such as regulatory or market pressures. But gradually, organisational forces in business itself are also suggested as drivers for the improvement of environmental performance (Andrews et al, 2001). Many companies have adopted systems approaches in their corporate strategy. Organisational strategies include quality, health and ...

  15. Essential amino acids: master regulators of nutrition and environmental footprint?

    OpenAIRE

    Tessari, Paolo; Lante, Anna; Mosca, Giuliano

    2016-01-01

    The environmental footprint of animal food production is considered several-fold greater than that of crops cultivation. Therefore, the choice between animal and vegetarian diets may have a relevant environmental impact. In such comparisons however, an often neglected issue is the nutritional value of foods. Previous estimates of nutrients? environmental footprint had predominantly been based on either food raw weight or caloric content, not in respect to human requirements. Essential amino a...

  16. Environmental regulation in the new exploration climate: After Rio, what next?

    International Nuclear Information System (INIS)

    Millison, D.

    1993-01-01

    Exploration activities of U.S.-headquartered petroleum companies have increasingly shifted to international targets, in large part due to excessive environmental regulation. However, governments hosting new exploration venues are promulgating environmental regulations, often based on U.S. EPA regulations, which affect the economics of oil and gas operations. New host-country regulations, combined with a growing worldwide open-quotes green movement,close quotes require the new exploration climate to be evaluated in terms of environmental restrictions on drilling, production, and downstream operations. Is the industry truly fleeing regulation, but destined to dead-end in a never-never land of dwindling opportunity? Or is there hope for a system of reasonable regulations which encourage open-quotes sustainable developmentclose quotes of new petroleum resources? The green movement now places a new burden on trade. Exporters must verify to open-quotes greenclose quotes consumers that their products are open-quotes environmentally friendlyclose quotes, effectively introducing a non-tariff trade restriction. The playing field of international trade is leveled by adaption of US or European-style environmental regulation. THe UNCED conference in Rio has further promoted a system of international environmental regulation which will likely grow stronger as globalization of trade increases. This presentation focuses on the increasing standardization of international regulations which affect petroleum development. Key issues discussed are: the effect of atmospheric emissions controls on energy development policy and petroleum operations, environmental regulations in Latin America-risk vs. technology-based policies, and linking environmental regulations and international trade

  17. Environmental regulation in the new exploration climate: After Rio, what next

    Energy Technology Data Exchange (ETDEWEB)

    Millison, D. (Ecology and Environment Inc., Houston, TX (United States))

    1993-02-01

    Exploration activities of U.S.-headquartered petroleum companies have increasingly shifted to international targets, in large part due to excessive environmental regulation. However, governments hosting new exploration venues are promulgating environmental regulations, often based on U.S. EPA regulations, which affect the economics of oil and gas operations. New host-country regulations, combined with a growing worldwide [open quotes]green movement,[close quotes] require the new exploration climate to be evaluated in terms of environmental restrictions on drilling, production, and downstream operations. Is the industry truly fleeing regulation, but destined to dead-end in a never-never land of dwindling opportunity Or is there hope for a system of reasonable regulations which encourage [open quotes]sustainable development[close quotes] of new petroleum resources The green movement now places a new burden on trade. Exporters must verify to [open quotes]green[close quotes] consumers that their products are [open quotes]environmentally friendly[close quotes], effectively introducing a non-tariff trade restriction. The playing field of international trade is leveled by adaption of US or European-style environmental regulation. THe UNCED conference in Rio has further promoted a system of international environmental regulation which will likely grow stronger as globalization of trade increases. This presentation focuses on the increasing standardization of international regulations which affect petroleum development. Key issues discussed are: the effect of atmospheric emissions controls on energy development policy and petroleum operations, environmental regulations in Latin America-risk vs. technology-based policies, and linking environmental regulations and international trade.

  18. Mechanisms for the environmental regulation of gene expression ...

    Indian Academy of Sciences (India)

    2005-01-07

    Jan 7, 2005 ... Keywords. Ecological developmental biology; environmental agents; symbiosis. Abstract. The environment can play a significant role in the production of phenotypes. However, the developmental mechanisms by which the environmental agents effect normal development are just becoming known. At least ...

  19. The regulation of the EC on the environmental impact statement

    International Nuclear Information System (INIS)

    Cupei, J.

    1985-01-01

    In March 1985, the Council of Ministers of the European Communities agreed on a draft directive for an environmental impact assessment. Preparations and difficult negotiations lasted for nearly ten years. An important step was the draft of the Commission of 1980. Besides the history of the draft topics of discussion are the following: Scope of the directive, procedural problems of the environmental impact assessment, phases of the investigation, content and scope of the assessment, periodical control of the installation and its environmental effects, problems of communication. (DR)

  20. Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (pppGpp synthase

    Directory of Open Access Journals (Sweden)

    Kalinowski Jörn

    2006-09-01

    Full Text Available Background The stringent response is the initial reaction of microorganisms to nutritional stress. During stringent response the small nucleotides (pppGpp act as global regulators and reprogram bacterial transcription. In this work, the genetic network controlled by the stringent response was characterized in the amino acid-producing Corynebacterium glutamicum. Results The transcriptome of a C. glutamicum rel gene deletion mutant, unable to synthesize (pppGpp and to induce the stringent response, was compared with that of its rel-proficient parent strain by microarray analysis. A total of 357 genes were found to be transcribed differentially in the rel-deficient mutant strain. In a second experiment, the stringent response was induced by addition of DL-serine hydroxamate (SHX in early exponential growth phase. The time point of the maximal effect on transcription was determined by real-time RT-PCR using the histidine and serine biosynthetic genes. Transcription of all of these genes reached a maximum at 10 minutes after SHX addition. Microarray experiments were performed comparing the transcriptomes of SHX-induced cultures of the rel-proficient strain and the rel mutant. The differentially expressed genes were grouped into three classes. Class A comprises genes which are differentially regulated only in the presence of an intact rel gene. This class includes the non-essential sigma factor gene sigB which was upregulated and a large number of genes involved in nitrogen metabolism which were downregulated. Class B comprises genes which were differentially regulated in response to SHX in both strains, independent of the rel gene. A large number of genes encoding ribosomal proteins fall into this class, all being downregulated. Class C comprises genes which were differentially regulated in response to SHX only in the rel mutant. This class includes genes encoding putative stress proteins and global transcriptional regulators that might be

  1. After 'dieselgate': Regulations or economic incentives for a successful environmental policy?

    Science.gov (United States)

    Zachariadis, Theodoros

    2016-08-01

    In September 2015 the U.S. Environmental Protection Agency announced that it started investigations against the automaker Volkswagen for illegally installing software that allowed some diesel-powered vehicle models to pass stringent emission tests for type-approval. Although generally prohibited, modern software makes it feasible for vehicles to detect an emission test and modulate engine operation or emission control accordingly. It has also been well known to experts worldwide - and readers of this Journal - that emission tests for motor vehicles are conducted with outdated test procedures which do not reflect today's actual driving conditions and enable automakers to exploit 'flexibilities' so as to yield artificially low emission results. For example, on-road carbon dioxide (CO2) emissions of cars that entered the European market in 2014 were reportedly 40% higher than their formal test emissions, while this gap was less than 10% in the early 2000s (Tietge et al., 2015). In the case of health-related pollutant nitrogen oxides (NOx), this gap seems to be markedly higher, in particular for diesel-powered cars (Weiss et al., 2012) - whereas this does not seem to be a serious problem for other air pollutants. In internal combustion engines of motor vehicles there is still a trade-off between NOx emissions and fuel efficiency (and hence CO2 emissions): a fast combustion with high temperatures is optimal for maximum fuel efficiency and minimum CO2 emissions, whereas these conditions give rise to higher NOx emissions. Conversely, NOx control techniques such as exhaust gas recirculation reduce combustion temperature and often lead to lower fuel efficiency. In short, it becomes ever more difficult for internal combustion engines to meet the increasingly stringent legislated standards for some air pollutants and carbon dioxide at the same time. This increases the probability of applying legal and illegal defeat strategies.

  2. Essential amino acids: master regulators of nutrition and environmental footprint?

    Science.gov (United States)

    Tessari, Paolo; Lante, Anna; Mosca, Giuliano

    2016-01-01

    The environmental footprint of animal food production is considered several-fold greater than that of crops cultivation. Therefore, the choice between animal and vegetarian diets may have a relevant environmental impact. In such comparisons however, an often neglected issue is the nutritional value of foods. Previous estimates of nutrients’ environmental footprint had predominantly been based on either food raw weight or caloric content, not in respect to human requirements. Essential amino acids (EAAs) are key parameters in food quality assessment. We re-evaluated here the environmental footprint (expressed both as land use for production and as Green House Gas Emission (GHGE), of some animal and vegetal foods, titrated to provide EAAs amounts in respect to human requirements. Production of high-quality animal proteins, in amounts sufficient to match the Recommended Daily Allowances of all the EAAs, would require a land use and a GHGE approximately equal, greater o smaller (by only ±1-fold), than that necessary to produce vegetal proteins, except for soybeans, that exhibited the smallest footprint. This new analysis downsizes the common concept of a large advantage, in respect to environmental footprint, of crops vs. animal foods production, when human requirements of EAAs are used for reference. PMID:27221394

  3. Adaptation to fluctuating temperatures in an RNA virus is driven by the most stringent selective pressure.

    Directory of Open Access Journals (Sweden)

    María Arribas

    Full Text Available The frequency of change in the selective pressures is one of the main factors driving evolution. It is generally accepted that constant environments select specialist organisms whereas changing environments favour generalists. The particular outcome achieved in either case also depends on the relative strength of the selective pressures and on the fitness costs of mutations across environments. RNA viruses are characterized by their high genetic diversity, which provides fast adaptation to environmental changes and helps them evade most antiviral treatments. Therefore, the study of the adaptive possibilities of RNA viruses is highly relevant for both basic and applied research. In this study we have evolved an RNA virus, the bacteriophage Qβ, under three different temperatures that either were kept constant or alternated periodically. The populations obtained were analyzed at the phenotypic and the genotypic level to characterize the evolutionary process followed by the virus in each case and the amount of convergent genetic changes attained. Finally, we also investigated the influence of the pre-existent genetic diversity on adaptation to high temperature. The main conclusions that arise from our results are: i under periodically changing temperature conditions, evolution of bacteriophage Qβ is driven by the most stringent selective pressure, ii there is a high degree of evolutionary convergence between replicated populations and also among populations evolved at different temperatures, iii there are mutations specific of a particular condition, and iv adaptation to high temperatures in populations differing in their pre-existent genetic diversity takes place through the selection of a common set of mutations.

  4. Environmental regulation impacts on international trade: aggregate and sectoral analyses with a bilateral trade flow model

    NARCIS (Netherlands)

    van Beers, C.; van den Bergh, J.C.J.M.

    2003-01-01

    An important barrier to the implementation of strict environmental regulations is that they are perceived to negatively affect a country's competitiveness, visible through changes in international trade. Whereas theoretical analyses of trade and the environment indicate that relatively strict

  5. 76 FR 72391 - Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense...

    Science.gov (United States)

    2011-11-23

    ... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2011-OS-0055] Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense Logistics Agency Actions AGENCY: Defense Logistics Agency, Department of Defense. ACTION: Revised Defense Logistics Agency...

  6. Evolutionary Game Analysis of Government Regulation and Enterprise Emission from the Perspective of Environmental Tax

    Science.gov (United States)

    Mai, Yazong

    2017-12-01

    In the context of the upcoming implementation of the environmental tax policy, there is a need for a focus on the relationship between government regulation and corporate emissions. To achieve the real effect of environmental tax policy, government need to regulate the illegal emissions of enterprises. Based on the hypothesis of bounded rationality, this paper analyses the strategic set of government regulators and polluting enterprises in the implementation of environmental tax policy. By using the evolutionary game model, the utility function and payoff matrix of the both sides are constructed, and the evolutionary analysis and strategy adjustment of the environmental governance target and the actual profit of the stakeholders are carried out. Thus, the wrong behaviours could be corrected so that the equilibrium of the evolutionary system can be achieved gradually, which could also get the evolutionary stable strategies of the government and the polluting enterprises in the implementation of environmental tax policy.

  7. Environmental legislation and the regulation of waste management in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-01

    This study examines the regulatory aspects of waste management in Sweden, with a particular emphasis on regulating organic compounds produced by waste-to-energy facilities. Since the early 1960s, waste-to-energy has played a significant role in managing waste in Sweden. In 1993, more than 50% of the municipal solid waste available for treatment or disposal following source separation efforts was processed in one of the 21 waste-to-energy facilities operating in Sweden. This report examines Sweden`s regulatory environment, its history of setting emission limits on waste management facilities, and the current status of regulations.

  8. Environmental Regulation, Economic Network and Sustainable Growth of Urban Agglomerations in China

    OpenAIRE

    Zhaohui Chong; Chenglin Qin; Xinyue Ye

    2016-01-01

    In this paper, we examine the influence of environmental regulation on sustainable economic growth from both theoretical and empirical perspectives. Our research is twofold. First, we apply a modified NEG (New Economic Geography) model to analyze how environmental regulation influences firms’ location choices and cities’ sustainable economic growth. Second, we test a spatial econometric model employing panel data of the three largest urban agglomerations in China from 2003 to 2013 to study th...

  9. Informal environmental regulation of industrial air pollution: Does neighborhood inequality matter?

    OpenAIRE

    Zwickl, Klara; Moser, Mathias

    2014-01-01

    This paper analyzes if neighborhood income inequality has an effect on informal regulation of environmental quality, using census tract-level data on industrial air pollution exposure from EPA´s Risk Screening Environmental Indicators and income and demographic variables from the American Community Survey and EPA´s Smart Location Database. Estimating a spatial lag model and controlling for formal regulation at the states level, we find evidence that overall neighborhood inequality - as measur...

  10. Environmental Regulation and Food Safety: Studies of Protection ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    HACCP is not confined to food production, however, but is also used in many other industries such as healthcare. 5. See Tsunehiro Otsukti ... The revised Uruguay Round Agreement now defines technical regulations as rules which refer to 'product characteristics and their related production methods'. However, this wording ...

  11. Review of Antimicrobial Resistance in the Environment and its Relevance to Environmental Regulators

    Directory of Open Access Journals (Sweden)

    Andrew C Singer

    2016-11-01

    Full Text Available The environment is increasingly being recognised for the role it might play in the global spread of clinically-relevant antibiotic resistance. Environmental regulators monitor and control many of the pathways responsible for the release of resistance-driving chemicals into the environment (e.g., antimicrobials, metals, biocides. Hence, environmental regulators should be contributing significantly to the development of global and national antimicrobial resistance (AMR action plans. It is argued that the lack of environment-facing mitigation actions included in existing AMR action plans is likely a function of our poor fundamental understanding of many of the key issues. Here, we aim to present the problem with AMR in the environment through the lens of an environmental regulator, using the Environment Agency (England’s regulator as an example from which parallels can be drawn globally. The issues that are pertinent to environmental regulators are drawn out to answer: What are the drivers and pathways of AMR? How do these relate to the normal work, powers and duties of environmental regulators? What are the knowledge gaps that hinder the delivery of environmental protection from AMR? We offer several thought experiments for how different mitigation strategies might proceed. We conclude that: 1 AMR Action Plans do not tackle all the potentially relevant pathways and drivers of AMR in the environment; and 2 AMR Action Plans are deficient, in part, because the science to inform policy is lacking and this needs to be addressed.

  12. Environmental Regulation, Economic Network and Sustainable Growth of Urban Agglomerations in China

    Directory of Open Access Journals (Sweden)

    Zhaohui Chong

    2016-05-01

    Full Text Available In this paper, we examine the influence of environmental regulation on sustainable economic growth from both theoretical and empirical perspectives. Our research is twofold. First, we apply a modified NEG (New Economic Geography model to analyze how environmental regulation influences firms’ location choices and cities’ sustainable economic growth. Second, we test a spatial econometric model employing panel data of the three largest urban agglomerations in China from 2003 to 2013 to study the relationship between environmental regulation and sustainable economic growth as well as the spillover channels of economic activities. The results reveal a remarkable negative effect of environmental regulation on economic growth. In addition, we find no sufficient evidence to prove the existence of long-term effects of environmental regulation on economic growth in the three urban agglomerations. Furthermore, using different weight matrices to illustrate the different economic networks of the urban agglomeration, we validate the difference in spillover mechanisms across these three urban agglomerations. Specifically, the disparity in environmental regulation acts as a spillover channel for the Yangtze River Delta and the Pearl River Delta, while it is not significant for Jing-Jin-Ji.

  13. Decree 435/994 Environmental Impacts : establish a standard joint complex named Evaluation Regulations

    International Nuclear Information System (INIS)

    1994-01-01

    The Regulation of Evaluation of environmental Impact in the chapter I art.2 item 14 it establishes that It will require the previous Environmental Authorization the activities that refer to the construction of production factories and transformation of Nuclear Energy r, without damage of that settled down for the articulate 215 of the law 16.226 of October 29 1991 [es

  14. Lobbying against Environmental Regulation vs. Lobbying for Loopholes

    OpenAIRE

    Andreas Polk; Armin Schmutzler

    2003-01-01

    We analyze the determinants of environmental policy when two firms engage in two types of lobbying against a restriction on allowed pollution: General lobbying increases the total amount of allowed pollution, which is beneficial for both firms. Private lobbying increases the individual pollution standard of the lobbying firm, but has a negative or zero effect on the allowed emissions of the competitor. We determine the lobbying equilibrium and discuss the resulting emission level. In many cas...

  15. Environmental Regulation: Effective or Defective? Assessing whether criminal sanctions provide adequate protection of the environment

    OpenAIRE

    Bethell, Emma

    2009-01-01

    Issues, such as climate change and global warming, have seen environmental protection grow in the global consciousness into something worthy and in need of regulation. In response, a number of laws have been enacted which make certain environmental actions criminal offences, enforced through the criminal justice system. These environmental crimes are enforced using the same mechanisms and must satisfy the same procedural safeguards as 'traditional' criminal offences in order to secure convict...

  16. Strict Liability Versus Policy and Regulation for Environmental Protection and Agricultural Waste Management in Malaysia

    Directory of Open Access Journals (Sweden)

    Mohd Bakri Ishak

    2010-01-01

    Full Text Available Basically, strict liability is part of the mechanism for expressing judgment or sentence by using direct evidence. This principle is very useful in order to obtain remedies from any damage either directly or indirectly. The principle in Rylands v Fletcher is responsible on imposing strict liability where if something brought onto land or collected there escapes liability under this rule can include not only the owner of land but also those who control or occupation on it. However, as a matter of fact, policy and regulation are also important in taking any action against any party who are responsible for environmental pollution or damage, which may include mismanagement of waste or industrial waste or agricultural waste. There are certain policies and regulations on environmental protection such as the National Environmental Policy, certain Acts and several regulations under the Environmental Quality Act 1974 (Act 127, which are very useful for agricultural waste management inter alia: Waters Act 1920 (Act 418, Environmental Quality (Prescribed Premises (Crude Palm Oil Regulations 1977, Environmental Quality (Prescribed Premises (Raw Natural Rubber Regulations 1978, Environmental Quality (Sewage and Industrial Effluents Regulations 1979, and Environmental Quality (Compounding of Offences Rules 1978. As a matter of fact, we should realize that time is of an essence for any parties which are involved in court cases and especially in avoiding the element of externality, which is commonly suffered by the government. In making this paper, therefore, some element of comparison with certain developed jurisdiction such as in the United Kingdom and Japan could not be avoided in order to obtain better outcome and to be more practical for the purpose of environmental protection and agricultural waste management.

  17. Eco-Efficiency Assessments as a Tool for Revealing the Environmental Improvement Potential of New Regulations

    Directory of Open Access Journals (Sweden)

    Ottar Michelsen

    2010-01-01

    Full Text Available Public regulations can result in improved environmental performance of products. In this paper eco-efficiency is used to assess the most likely outcome of potential new regulations. The paper presents a case study of furniture production in Norway where different scenarios for improving the environmental performance of the products are presented. Four regulatory options for imposing environmental improvements are assessed; (1 an introduction of a tax on emissions, (2 an increase of the tax on landfills, (3 an introduction of a tax on raw material consumption, and (4 introduction of take-back legislation.

  18. Environmental laws regulating chemicals: Uses of information in decision making under environmental statutes

    Energy Technology Data Exchange (ETDEWEB)

    Gaba, J.M. [Southern Methodist Univ., Dallas, TX (United States)

    1990-12-31

    Three areas are addressed in this paper: generic issues that arise simply in the process of decision-making under environmental statutes; different decision-making standards under various environmental statutes; and efforts to legislate a {open_quotes}safe{close_quotes} or {open_quotes}acceptable{close_quotes} risk from exposure to carcinogenic chemicals.

  19. Leading trends in environmental regulation that affect energy development. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Steele, R V; Attaway, L D; Christerson, J A; Kikel, D A; Kuebler, J D; Lupatkin, B M; Liu, C S; Meyer, R; Peyton, T O; Sussin, M H

    1980-01-01

    Major environmental issues that are likely to affect the implementation of energy technologies between now and the year 2000 are identified and assessed. The energy technologies specifically addressed are: oil recovery and processing; gas recovery and processing; coal liquefaction; coal gasification (surface); in situ coal gasification; direct coal combustion; advanced power systems; magnetohydrodynamics; surface oil shale retorting; true and modified in situ oil shale retorting; geothermal energy; biomass energy conversion; and nuclear power (fission). Environmental analyses of these technologies included, in addition to the main processing steps, the complete fuel cycle from resource extraction to end use. A comprehensive survey of the environmental community (including environmental groups, researchers, and regulatory agencies) was carried out in parallel with an analysis of the technologies to identify important future environmental issues. Each of the final 20 issues selected by the project staff has the following common attributes: consensus of the environmental community that the issue is important; it is a likely candidate for future regulatory action; it deals with a major environmental aspect of energy development. The analyses of the 20 major issues address their environmental problem areas, current regulatory status, and the impact of future regulations. These analyses are followed by a quantitative assessment of the impact on energy costs and nationwide pollutant emissions of possible future regulations. This is accomplished by employing the Strategic Environmental Assessment System (SEAS) for a subset of the 20 major issues. The report concludes with a more general discussion of the impact of environmental regulatory action on energy development.

  20. Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family

    DEFF Research Database (Denmark)

    Kristensen, Ole; Laurberg, Martin; Liljas, Anders

    2004-01-01

    Exopolyphosphatase/guanosine pentaphosphate phosphohydrolase (PPX/GPPA) enzymes play central roles in the bacterial stringent response induced by starvation. The high-resolution crystal structure of the putative Aquifex aeolicus PPX/GPPA phosphatase from the actin-like ATPase domain superfamily h...

  1. Environmental Policies, Product Market Regulation and Innovation in Renewable Energy

    International Nuclear Information System (INIS)

    Nesta, Lionel; Vona, Francesco; Nicolli, Francesco

    2012-10-01

    We investigate the effectiveness of policies in favor of innovation in renew- able energy under different levels of competition. Using information regarding renewable energy policies, product market regulation and high-quality green patents for OECD countries since the late 1970's, we develop a pre-sample mean count-data econometric specification that also accounts for the endogeneity of policies. We find that renewable energy policies are significantly more effective in fostering green innovation in countries with deregulated energy markets. We also find that public support for renewable energy is crucial only in the generation of high-quality green patents, whereas competition enhances the generation of green patents irrespective of their quality. (authors)

  2. Environmental compliance assessment review

    International Nuclear Information System (INIS)

    Hilliday, G.H.

    1991-01-01

    During the period 1972-1991, The United States Congress passed stringent environmental statues which the Environment Protection Agency implemented via regulations. The statues and regulations contain severe civil and criminal penalties. Civil violations resulted in fines, typically payable by the company. The act of willfully and knowingly violating the permit conditions or regulations can result in criminal charges being imposed upon the responsible part, i.e., either the company or individual. Criminal charges can include fines, lawyer fees, court costs and incarceration. This paper describes steps necessary to form an effective Environmental Compliance Assessment Review [CAR] program, train field and engineering personnel and perform a CAR audit. Additionally, the paper discusses the findings of a number of Exploration and Production [E and P] field audits

  3. Can local environmental regulation of companies deal with a broader environmental view?

    DEFF Research Database (Denmark)

    Dirckinck-Holmfeld, Kasper; Smink, Carla

    Environmental concern of companies has gradually expanded from a focus on local environmental problems to a broader inclusion of inputs as well as lifecycle perspectives. At the same time, the regulatory approach has changed from a “pure” command-and-control regime, towards a governance regime...... to include more facilitating and catalytic aspects as well as promoting cleaner technology and pollution prevention have been tried out. However today, most municipalities still rely on traditional command-and-control mechanisms as well as targeting at the traditional local environmental concerns. However...... the reason years renewed focus on Climate and Energy seems to provide perspectives to reintroduces this more facilitating role and focus on broader environmental aspects....

  4. Survey of environmental regulations applying to geothermal exploration, development, and use.

    Energy Technology Data Exchange (ETDEWEB)

    Beeland, G.V.

    1984-03-01

    Federal, State, and local environmental laws and regulations that apply to geothermal energy development are summarized. Most attention is given to those regulations which deal with air pollution, water pollution, solid wastes and impact assessments. Analyses are made of the regulations with respect to resource definition, pollutants currently not controlled, duplicity and overlap in permit and impact assessment requirements, the lack of uniformity of regulations between states, and the probable future approaches to the regulatory problems. This project updates a similar document (EPA/600/7-78-014) dated February 1978.

  5. Impact of Executive Order 13211 on environmental regulation: An empirical study

    International Nuclear Information System (INIS)

    Geltman, Elizabeth Glass; Gill, Gunwant; Jovanovic, Miriam

    2016-01-01

    A great deal has been written about the Energy Policy Act of 2005 exempting oil and gas operations using hydraulic fracturing from the purview of certain federal environmental laws. Far less attention has been paid to George W. Bush's Executive Order 13211 (EO 13211), entitled “Actions Concerning Regulations that Significantly Affect Energy Supply, Distribution or Use.” The Executive Order requires federal agencies to evaluate the impact of federal regulations on “supply, distribution and use of energy.” This study examined the impact of EO 13211 on United States environmental and conservation regulations proposed and promulgated by federal agencies. The study found that during rule making proceedings, EO 13211 had almost no effect on environmental and conservation actions taken by federal agencies. Most federal agency rules, both proposed and final, evaluating energy impacts pursuant to EO 13211 found no “significant energy action” and accordingly did not necessitate further regulatory review. In most cases, energy evaluation was routine, did not alter environmental or health policy and was reflected in brief, boilerplate language. - Highlights: • We examined the impact of Executive Order 13211 on US environmental and conservation regulations. • EO 13211 had little effect on environmental and conservation actions during federal rulemaking. • Most agencies found no “significant energy action” and no need for detailed regulatory review.

  6. Determinants of Renewable Energy Innovation: Environmental Policies vs. Market Regulation

    International Nuclear Information System (INIS)

    Vona, Francesco; Nesta, Lionel; Nicolli, Francesco

    2012-02-01

    This paper carries out a comprehensive analysis of renewable energy innovations considering four mechanisms suggested by innovation models: 1. policy-inducement; 2. market structure; 3. demand and social cohesion- mainly proxied by income inequality; 4. characteristics of country knowledge base. For OECD countries and years 1970-2005, we build a unique dataset containing time-varying information on quality-adjusted patent production in renewable energy, the latter being a function of environmental policies, green R and D, entry barriers, knowledge stock, knowledge diversity and income inequality. We develop count data models using the Generalized Method of Moments (GMM) to account for endogeneity of policy support. Our synthetic policy index positively affects innovations especially in countries with deregulated energy markets and low entry barriers. The effect of entry barriers and inequality is negative and of similar magnitude as that of policy. Product market liberalization positively affects green patent generation, especially so when ambitious policies are adopted, when the initial level of public R and D expenditures and when the initial share of distributed energy generation is high. Our results are robust to alternative specifications, to the inclusion of technology-specific effects and to the use of quality-adjusted patents as dependent variables. In the latter case, the estimated effect of lowering entry barriers and of knowledge diversity almost double on citation count relatively to patent count. (authors)

  7. Source to sink transport and regulation by environmental factors

    Directory of Open Access Journals (Sweden)

    Remi eLemoine

    2013-07-01

    Full Text Available Source-to-sink transport of sugar is one of the major determinants of plant growth and relies on the efficient and controlled distribution of sucrose (and some other sugars such as raffinose and polyols across plant organs through the phloem. However, sugar transport through the phloem can be affected by many environmental factors that alter source/sink relationships. In this paper, we summarize current knowledge about the phloem transport mechanisms and review the effects of several abiotic (water and salt stress, mineral deficiency, CO2, light, temperature, air and soil pollutants and biotic (mutualistic and pathogenic microbes, viruses, aphids and parasitic plants factors. Concerning abiotic constraints, alteration of the distribution of sugar among sinks is often reported, with some sinks as roots favoured in case of mineral deficiency. Many of these constraints impair the transport function of the phloem but the exact mechanisms are far from being completely known. Phloem integrity can be disrupted (e.g. by callose deposition and under certain conditions, phloem transport is affected, earlier than photosynthesis. Photosynthesis inhibition could result from the increase in sugar concentration due to phloem transport decrease. Biotic interactions (aphids, fungi, viruses… also affect crop plant productivity. Recent breakthroughs have identified some of the sugar transporters involved in these interactions on the host and pathogen sides. The different data are discussed in relation to the phloem transport pathways. When possible, the link with current knowledge on the pathways at the molecular level will be highlighted.

  8. Quorum Regulated Resistance of Vibrio cholerae against Environmental Bacteriophages.

    Science.gov (United States)

    Hoque, M Mozammel; Naser, Iftekhar Bin; Bari, S M Nayeemul; Zhu, Jun; Mekalanos, John J; Faruque, Shah M

    2016-11-28

    Predation by bacteriophages can significantly influence the population structure of bacterial communities. Vibrio cholerae the causative agent of cholera epidemics interacts with numerous phages in the aquatic ecosystem, and in the intestine of cholera patients. Seasonal epidemics of cholera reportedly collapse due to predation of the pathogen by phages. However, it is not clear how sufficient number of the bacteria survive to seed the environment in the subsequent epidemic season. We found that bacterial cell density-dependent gene expression termed "quorum sensing" which is regulated by signal molecules called autoinducers (AIs) can protect V. cholerae against predatory phages. V. cholerae mutant strains carrying inactivated AI synthase genes were significantly more susceptible to multiple phages compared to the parent bacteria. Likewise when mixed cultures of phage and bacteria were supplemented with exogenous autoinducers CAI-1 or AI-2 produced by recombinant strains carrying cloned AI synthase genes, increased survival of V. cholerae and a decrease in phage titer was observed. Mutational analyses suggested that the observed effects of autoinducers are mediated in part through the quorum sensing-dependent production of haemaglutinin protease, and partly through downregulation of phage receptors. These results have implication in developing strategies for phage mediated control of cholera.

  9. Regulation Systems of Bacteria such as Escherichia coli in Response to Nutrient Limitation and Environmental Stresses

    Directory of Open Access Journals (Sweden)

    Kazuyuki Shimizu

    2013-12-01

    Full Text Available An overview was made to understand the regulation system of a bacterial cell such as Escherichia coli in response to nutrient limitation such as carbon, nitrogen, phosphate, sulfur, ion sources, and environmental stresses such as oxidative stress, acid shock, heat shock, and solvent stresses. It is quite important to understand how the cell detects environmental signals, integrate such information, and how the cell system is regulated. As for catabolite regulation, F1,6B P (FDP, PEP, and PYR play important roles in enzyme level regulation together with transcriptional regulation by such transcription factors as Cra, Fis, CsrA, and cAMP-Crp. αKG plays an important role in the coordinated control between carbon (C- and nitrogen (N-limitations, where αKG inhibits enzyme I (EI of phosphotransferase system (PTS, thus regulating the glucose uptake rate in accordance with N level. As such, multiple regulation systems are co-ordinated for the cell synthesis and energy generation against nutrient limitations and environmental stresses. As for oxidative stress, the TCA cycle both generates and scavenges the reactive oxygen species (ROSs, where NADPH produced at ICDH and the oxidative pentose phosphate pathways play an important role in coping with oxidative stress. Solvent resistant mechanism was also considered for the stresses caused by biofuels and biochemicals production in the cell.

  10. 10 CFR 51.10 - Purpose and scope of subpart; application of regulations of Council on Environmental Quality.

    Science.gov (United States)

    2010-01-01

    ... of Council on Environmental Quality. 51.10 Section 51.10 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy Act-Regulations Implementing Section 102(2) § 51.10 Purpose and scope of...

  11. Competition policies and environmental quality: Empirical analysis of the electricity sector in OECD countries

    International Nuclear Information System (INIS)

    Asane-Otoo, Emmanuel

    2016-01-01

    Over the last decades, electricity markets across OECD countries have been subjected to profound structural changes with far-reaching implications on the economy and the environment. This paper investigates the effect of restructuring – changes in entry regulations, the degree of vertical integration and ownership structure – on GHG emissions. The findings show that competition policies – particularly reducing the degree of vertical integration and increasing privatization – correlate negatively with emission intensity. However, the environmental effect of reducing market entry barriers is generally insignificant. Integration of competition and stringent environmental policies are required to reduce GHG emissions and improve environmental quality. - Highlights: •Empirical study on competition policies and GHG emissions from the electricity sector. •Product market regulation scores for OECD countries are used to measure the extent of competition. •Evidence of a positive relationship between competition policies and environmental quality. •Integration of competition and stringent environmental policies is recommended.

  12. Genetic and environmental influences on emotion regulation: A twin study of cognitive reappraisal and expressive suppression.

    Science.gov (United States)

    McRae, Kateri; Rhee, Soo Hyun; Gatt, Justine M; Godinez, Detre; Williams, Leanne M; Gross, James J

    2017-08-01

    Previous studies have established that personality traits related to emotionality are moderately heritable. However, the relative heritability of the strategies people use to regulate emotions is unknown. The present study compared the magnitude of additive genetic, shared environmental, and nonshared environmental influences on 2 commonly used emotion regulation strategies: cognitive reappraisal and expressive suppression. In 743 twin pairs (1,486 twins), we replicated previous estimates of heritability of neuroticism (a2 = .41). Furthermore, cognitive reappraisal was significantly less heritable and more influenced by nonshared environment (a2 = .20; e2 = .80) than either neuroticism or suppression (a2 = .35; e2 = .65), another emotion regulation strategy. Finally, Cholesky decomposition modeling suggested that while there were common genetic and environmental influences on neuroticism, reappraisal and suppression, there were also significant nonshared environmental influences common between reappraisal and adaptive emotional functioning after controlling for neuroticism and suppression. These findings highlight that different aspects of emotional processing, even the use of different emotion regulation strategies, are differentially heritable. The importance of the nonshared environmental influences specific to reappraisal and adaptive emotional functioning speaks to the potential impact of social context, social partners, and psychosocial interventions on reappraisal habits. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Regulating the environmental impacts of factory farming in South Africa: legal perspectives

    OpenAIRE

    Grobler, Ruché

    2012-01-01

    The main purpose of this study was to determine the impact of factory farming on the environment in South Africa. It also determined whether the current existing environmental legislation in the country adequately regulates the growing industry. The various impacts that factory farms may have on the environment are discussed in detail and they include water pollution, air pollution and desertification. The applicable laws are discussed in detail and also applied to the environmental impact...

  14. Consumers' Ecological Awareness, Environmental Regulation and MNCs' Choices in a Global Economy

    OpenAIRE

    Fabrice Darrigues; Jean-Marc Montaud

    2012-01-01

    Using a monopolistic competition model with mobile capital, in which firms may choose between ¡°dirty¡± or ¡°clean¡± technology, this paper investigates the relationship between the environment, trade liberalization, and the geographical and technical choices of multinational firms. Simulation results show that beyond environmental regulations, the ecological sensitivity of consumers can serve as a market mechanism that urges firms to self-regulate. In particular, local sensitivity to environ...

  15. Hold-up Problems with Respect to R&D Investment and Licensing in Environmental Regulation

    OpenAIRE

    Breitscheidel, Jörg

    2005-01-01

    We explore the design of self-financing tax-subsidy schemes to solve hold-up problems in environmental regulation. The announcement of the tax rate seems to be preferable to solve hold-up problems with respect to the investment in environmental R&D. In contrast, only the announcement of the subsidy rate is adequate to solve hold-up problems with respect to the licensing of environmentally friendly technologies. Altogether, the announcement of the subsidy rate yields higher expected social wel...

  16. 76 FR 53119 - Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense...

    Science.gov (United States)

    2011-08-25

    ... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2011-OS-0055] Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense Logistics Agency Actions AGENCY: Defense Logistics Agency, Department of Defense. ACTION: Comment Addressed on Notice of...

  17. 76 FR 28757 - Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense...

    Science.gov (United States)

    2011-05-18

    ... DEPARTMENT OF DEFENSE Office of the Secretary [DOCKET ID DOD-2011-OS-0055] Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense Logistics Agency Actions AGENCY: Defense Logistics Agency, Department of Defense. ACTION: Notice of Availability (NOA) of Revised...

  18. Genetic and Environmental Regulation on Longitudinal Change of Metabolic Phenotypes in Danish and Chinese Adult Twins

    DEFF Research Database (Denmark)

    Li, Shuxia; Kyvik, Kirsten Ohm; Pang, Zengchang

    2016-01-01

    OBJECTIVE: The rate of change in metabolic phenotypes can be highly indicative of metabolic disorders and disorder-related modifications. We analyzed data from longitudinal twin studies on multiple metabolic phenotypes in Danish and Chinese twins representing two populations of distinct ethnic, c...... differential patterns of genetic and common environmental regulation on changes over time in metabolic phenotypes across the two samples....

  19. 75 FR 8299 - Draft Environmental Impact Statement; Determination of Regulated Status of Alfalfa Genetically...

    Science.gov (United States)

    2010-02-24

    ...] Draft Environmental Impact Statement; Determination of Regulated Status of Alfalfa Genetically... making a determination on the status of the Monsanto Company and Forage Genetics International alfalfa... status of the Monsanto Company and Forage Genetics International alfalfa lines designated as events J101...

  20. Environmental cues from CNS, PNS, and ENS cells regulate CNS progenitor differentiation

    DEFF Research Database (Denmark)

    Brännvall, Karin; Corell, Mikael; Forsberg-Nilsson, Karin

    2008-01-01

    Cellular origin and environmental cues regulate stem cell fate determination. Neuroepithelial stem cells form the central nervous system (CNS), whereas neural crest stem cells generate the peripheral (PNS) and enteric nervous system (ENS). CNS neural stem/progenitor cell (NSPC) fate determination...

  1. Energy-economy relationship and environmental regulation in the presence of unrecorded economy

    International Nuclear Information System (INIS)

    Karanfil, F.

    2008-12-01

    This PhD thesis including five manuscripts and a brief international comparison analysis proposes a multi-field study on the economic and environmental effects of energy consumption. It first investigates the causal relationship between economic growth and energy consumption in Turkey and then offers a new methodology for the estimation of unrecorded economy based on environmental data. The thesis develops also asymmetric information models, where the regulator does not know the true emission level of each firm that it wishes to regulate, so as to examine to what extend different enforcement mechanisms affect incentives for the firms to reduce polluting emissions and to invest in clean energy technologies. In order to provide a complete insight on the effects of both fiscal and environmental enforcement policies, some similar analysis are conducted taking into account the existence of unrecorded economy. The results in this thesis essentially show that: first, energy conservation policies can be implemented in order to reduce greenhouse gas emissions without any adverse effect on the recorded economic activities; second, different audit mechanisms should be used depending on the environmental objective of the enforcement agency; third, in some cases, environmental regulations may increase the size of unrecorded economy; fourth, economic policies to combat unrecorded economy may not serve as a complement to energy conservation policies. (author)

  2. Implications of environmental regulations on refinery product specification, operation and investment

    International Nuclear Information System (INIS)

    Amin, M.M.

    1992-01-01

    During the 1980s, refiners mainly in OECD countries were occupied with improving their refinery configurations for producing high-value light products which would not only satisfy the product demand slate but also meet the increasingly restrictive environmental regulations. In the 1990s refiners will continue to be challenged to improve the world's air quality not only by producing products that minimize emissions of toxic and hazardous hydrocarbons, but also through the refinery operation itself by investment in upgrading the industry and products to cope with the constant flow of new regulations. These investments will not only be limited to consuming centres but will also be extended to cover exporting refineries as well due to competition of acquiring market shares for product exports. The additional cost will be directly related to product quality and site regulations and will vary from one country to the other. This paper deals mainly with the air pollution and the impact of related environmental issues on the refining industry. Environmental regulations for refinery products in the USA and Europe are examined and international regulations for the tanker industry are noted. (author)

  3. Coordinated regulation of photosynthesis in rice increases yield and tolerance to environmental stress.

    Science.gov (United States)

    Ambavaram, Madana M R; Basu, Supratim; Krishnan, Arjun; Ramegowda, Venkategowda; Batlang, Utlwang; Rahman, Lutfor; Baisakh, Niranjan; Pereira, Andy

    2014-10-31

    Plants capture solar energy and atmospheric carbon dioxide (CO2) through photosynthesis, which is the primary component of crop yield, and needs to be increased considerably to meet the growing global demand for food. Environmental stresses, which are increasing with climate change, adversely affect photosynthetic carbon metabolism (PCM) and limit yield of cereals such as rice (Oryza sativa) that feeds half the world. To study the regulation of photosynthesis, we developed a rice gene regulatory network and identified a transcription factor HYR (HIGHER YIELD RICE) associated with PCM, which on expression in rice enhances photosynthesis under multiple environmental conditions, determining a morpho-physiological programme leading to higher grain yield under normal, drought and high-temperature stress conditions. We show HYR is a master regulator, directly activating photosynthesis genes, cascades of transcription factors and other downstream genes involved in PCM and yield stability under drought and high-temperature environmental stress conditions.

  4. Effects of environmental regulations on heavy metal pollution decline in core sediments from Manila Bay

    International Nuclear Information System (INIS)

    Hosono, Takahiro; Su, Chih-Chieh; Siringan, Fernando; Amano, Atsuko; Onodera, Shin-ichi

    2010-01-01

    We investigated the high-resolution heavy metal pollution history of Manila Bay using heavy metal concentrations and Pb isotope ratios together with 210 Pb dating to find out the effects of environmental regulations after the 1990s. Our results suggested that the rate of decline in heavy metal pollution increased dramatically from the end of the 1990s due to stricter environmental regulations, Administrative Order No. 42, being enforced by the Philippines government. The presented data and methodology should form the basis for future monitoring, leading to pollution control, and to the generation of preventive measures at the pollution source for the maintenance of environmental quality in the coastal metropolitan city of Manila. Although this is the first report of a reduction in pollution in Asian developing country, our results suggest that we can expect to find similar signs of pollution decline in other parts of the world as well.

  5. Environmental Regulation

    Data.gov (United States)

    Kansas Data Access and Support Center — KR305b 1994 coverage, used to support water quality programs, references water quality use designations and support levels. The KR305b 1994 coverage is available for...

  6. Can Environmental Regulations Promote Corporate Environmental Responsibility? Evidence from the Moderated Mediating Effect Model and an Empirical Study in China

    Directory of Open Access Journals (Sweden)

    Benhong Peng

    2018-02-01

    Full Text Available Based on the Stakeholder theory, a moderated mediating effect model is developed to reach the study objective, revealing an important connection that suggests environmental regulations (ERs influence corporate environmental responsibility (CER (Porter Hypothesis. In building the model, the validity of the questionnaire data was analyzed with factor analysis. By employing a two-step approach, a regression analysis is utilized to discuss the mediating effect of altruistic motivation and moderating effect of green innovation, and a structural equation model is used to explore the interactive mechanism of different variables. It is found that altruistic motivation plays a medium role in the relationship between ERs and CER, and green innovation engages a positive coordination in the relationship. The empirical study identifies factors affecting enterprises’ willingness to undertake environmental responsibility, including environment policies, corporate culture, and personal characters among others. It is also revealed that altruistic motivation is conducive to forming a community interests among enterprises and enhancing their resistance to market risks, which explains and corroborates the Stakeholder theory; and the higher the level of green innovation, the more willing enterprises are to implement environmentally friendly operations.

  7. Environmental Regulation, Foreign Direct Investment and Green Technological Progress—Evidence from Chinese Manufacturing Industries

    Directory of Open Access Journals (Sweden)

    Jiangfeng Hu

    2018-01-01

    Full Text Available This study examines the spillover effects of foreign direct investment (FDI on green technology progress rate (as measured by the green total factor productivity. The analysis utilizes two measures of FDI, labor-based FDI and capital-based FDI, and separately investigates four sets of industry classifications—high/low discharge regulation and high/low emission standard regulation. The results indicate that in the low discharge regulation and low emission standard regulation industry, labor-based FDI has a significant negative spillover effect, and capital-based FDI has a significant positive spillover effect. However, in the high-intensity environmental regulation industry, the negative influence of labor-based FDI is completely restrained, and capital-based FDI continues to play a significant positive green technological spillover effects. These findings have clear policy implications: the government should be gradually reducing the labor-based FDI inflow or increasing stringency of environmental regulation in order to reduce or eliminate the negative spillover effect of the labor-based FDI.

  8. Environmental Regulation, Foreign Direct Investment and Green Technological Progress-Evidence from Chinese Manufacturing Industries.

    Science.gov (United States)

    Hu, Jiangfeng; Wang, Zhao; Lian, Yuehan; Huang, Qinghua

    2018-01-29

    This study examines the spillover effects of foreign direct investment (FDI) on green technology progress rate (as measured by the green total factor productivity). The analysis utilizes two measures of FDI, labor-based FDI and capital-based FDI, and separately investigates four sets of industry classifications-high/low discharge regulation and high/low emission standard regulation. The results indicate that in the low discharge regulation and low emission standard regulation industry, labor-based FDI has a significant negative spillover effect, and capital-based FDI has a significant positive spillover effect. However, in the high-intensity environmental regulation industry, the negative influence of labor-based FDI is completely restrained, and capital-based FDI continues to play a significant positive green technological spillover effects. These findings have clear policy implications: the government should be gradually reducing the labor-based FDI inflow or increasing stringency of environmental regulation in order to reduce or eliminate the negative spillover effect of the labor-based FDI.

  9. Environmental Regulation, Foreign Direct Investment and Green Technological Progress—Evidence from Chinese Manufacturing Industries

    Science.gov (United States)

    Hu, Jiangfeng; Wang, Zhao; Lian, Yuehan; Huang, Qinghua

    2018-01-01

    This study examines the spillover effects of foreign direct investment (FDI) on green technology progress rate (as measured by the green total factor productivity). The analysis utilizes two measures of FDI, labor-based FDI and capital-based FDI, and separately investigates four sets of industry classifications—high/low discharge regulation and high/low emission standard regulation. The results indicate that in the low discharge regulation and low emission standard regulation industry, labor-based FDI has a significant negative spillover effect, and capital-based FDI has a significant positive spillover effect. However, in the high-intensity environmental regulation industry, the negative influence of labor-based FDI is completely restrained, and capital-based FDI continues to play a significant positive green technological spillover effects. These findings have clear policy implications: the government should be gradually reducing the labor-based FDI inflow or increasing stringency of environmental regulation in order to reduce or eliminate the negative spillover effect of the labor-based FDI. PMID:29382112

  10. Egyptian Environmental Activities and Regulations for Management of Hazardous Substances and Hazardous Wastes

    International Nuclear Information System (INIS)

    El Zarka, M.

    1999-01-01

    A substantial use of hazardous substances is essential to meet the social and economic goals of the community in Egypt. Agrochemicals are being used extensively to increase crop yield. The outdated agrochemicals and their empty containers represent a serious environmental problem. Industrial development in different sectors in Egypt obligates handling of huge amounts of hazardous substances and hazardous wastes. The inappropriate handling of such hazardous substances creates several health and environmental problems. Egypt faces many challenges to control safe handling of such substances and wastes. Several regulations are governing handling of hazardous substances in Egypt. The unified Environmental Law 4 for the year 1994 includes a full chapter on the Management of Hazardous Substances and Hazardous Wastes. National and international activities have been taken to manage hazardous substances and hazardous wastes in an environmental sound manner

  11. Environmental regulation of households. An empirical review of economic and psychological factors

    International Nuclear Information System (INIS)

    Van den Bergh, Jeroen C.J.M.

    2008-01-01

    The literature on sustainable consumption and environmental regulation of household behavior is dominated by conceptual and normative approaches. As a result, many suggestions lack a firm empirical basis. To overcome this deficiency, econometric studies in three areas of environmentally relevant activities of households are reviewed: residential use of energy, generation of solid waste and recycling, and residential use of water. Next to price and income elasticities, attention is devoted to individual socio-economic features and psychological factors, such as attitudes, knowledge, perceptions and values. Potential psychological determinants and related insights are further examined by discussing a range of representative and illustrative statistical-psychological studies of environmental behavior. One important general finding is that there are very few empirical studies that systematically combine socio-economic and psychological determinants. A range of insights for environmental policy is derived, and research recommendations are offered. (author)

  12. Life cycle environmental impacts of vacuum cleaners and the effects of European regulation

    International Nuclear Information System (INIS)

    Gallego-Schmid, Alejandro; Mendoza, Joan Manuel F.; Jeswani, Harish Kumar; Azapagic, Adisa

    2016-01-01

    Energy efficiency of vacuum cleaners has been declining over the past decades while at the same time their number in Europe has been increasing. The European Commission has recently adopted an eco-design regulation to improve the environmental performance of vacuum cleaners. In addition to the existing directive on waste electrical and electronic equipment (WEEE), the regulation could potentially have significant effects on the environmental performance of vacuum cleaners. However, the scale of the effects is currently unknown, beyond scant information on greenhouse gas emissions. Thus, this paper considers for the first time life cycle environmental impacts of vacuum cleaners and the effects of the implementation of these regulations at the European level. The effects of electricity decarbonisation, product lifetime and end-of-life disposal options are also considered. The results suggest that the implementation of the eco-design regulation alone will reduce significantly the impacts from vacuum cleaners (37%–44%) by 2020 compared with current situation. If business as usual continued and the regulation was not implemented, the impacts would be 82%–109% higher by 2020 compared to the impacts with the implementation of the regulation. Improvements associated with the implementation of the WEEE directive will be much smaller (< 1% in 2020). However, if the WEEE directive did not exist, then the impacts would be 2%–21% higher by 2020 relative to the impacts with the implementation of the directive. Further improvements in most impacts (6%–20%) could be achieved by decarbonising the electricity mix. Therefore, energy efficiency measures must be accompanied by appropriate actions to reduce the environmental impacts of electricity generation; otherwise, the benefits of improved energy efficiency could be limited. Moreover, because of expected lower life expectancy of vacuum cleaners and limited availability of some raw materials, the eco-design regulation should

  13. Environmental regulation and competition in the U.S. electricity industry

    International Nuclear Information System (INIS)

    Peck, S.C.; Weyant, J.P.

    1990-01-01

    The structural evolution of the electric utility industry, with reference to its dynamics with environmental regulation, is described, explicitly including suppliers to the industry, the consumers of the products of the industry, and the industries that produce substitutes for the products. The structure of the industry has changed dramatically over the years 1970-1990, and is likely to continue to evolve throughout the 1990s. This evolution has resulted from changes in the milieu within which the industry operates, for example changes in fuel and capital markets, as well as federal, state and local regulations governing its activities. The environmental regulations of the 1970s have had a significant impact on the structure, behavior and performance of the industry and changes in the structure have had a feedback effect on the types of environmental regulations likely to be successful within the industry in reducing emissions of SO 2 , NOx and CO 2 . This and numerous other studies using the framework designed by Michael Porter of the Harvard Business School have demonstrated that this expanded view of competition frequently provides a much better explanation for changes in industry structure and corporate strategy than conventional analyses. 10 refs., 3 figs

  14. Environmental regulation and competitiveness: Empirical evidence on the Porter Hypothesis from European manufacturing sectors

    International Nuclear Information System (INIS)

    Rubashkina, Yana; Galeotti, Marzio; Verdolini, Elena

    2015-01-01

    This paper investigates the “weak” and “strong” versions of Porter Hypothesis (PH) focusing on the manufacturing sectors of 17 European countries between 1997 and 2009. The hypothesis that well-crafted and well-enforced regulation would benefit both the environment and the firm was originally proposed by Porter (1991) and Porter and van der Linde (1995). To date, the literature has analyzed the impact of environmental regulation on innovation and on productivity mostly in separate analyses and focusing on the USA. The few existing contributions on Europe study the effect of environmental regulation either on green innovation or on performance indicators such as exports. We instead look at overall innovation and productivity impacts. First, focusing on overall innovative activity allows us to account for potential opportunity costs of induced innovations. Second, productivity impacts are arguably the most relevant indicators for the “strong” PH. As a proxy of environmental policy stringency we use pollution abatement and control expenditures (PACE), one of the few sectoral level indicators available. We remedy upon its main drawback, namely potential endogeneity, by adopting an instrumental variable estimation approach. We find evidence of a positive impact of environmental regulation on the output of innovation activity, as proxied by patents, thus providing support in favor of the “weak” PH. This result is in line with most of the literature. On the other front, we find no evidence in favor of the “strong” PH, as productivity appears to be unaffected by the degree of pollution control and abatement efforts. -- Highlights: •Weak and strong Porter Hypothesis. •Panel of manufacturing sectors of 17 European countries between 1997 and 2009. •Look at overall innovation and productivity impacts. •Pollution abatement & control expenditures proxy of environmental policy stringency. •Account for potential endogeneity of PACE by adopting

  15. The Application of Biodiesel as an Environmental Friendly Drilling Fluid to Drill Oil and Gas Wells

    OpenAIRE

    Ismail, Abdul Razak

    2014-01-01

    The oil and gas industries need to use oil based drilling fluids to drill troublesome rock layers such as sensitive shale formation or to drill very deep oil and gas wells. However, using oil based drilling fluids will create pollution and therefore, environmental regulations on discharge of such drilling fluids have become more stringent because it will give tremendous impacts on the marine life and ecosystem. This research is conducted to formulate a new environmental friendly drilling flui...

  16. Plant responses to environmental stress: regulation and functions of the Arabidopsis TCH genes

    Science.gov (United States)

    Braam, J.; Sistrunk, M. L.; Polisensky, D. H.; Xu, W.; Purugganan, M. M.; Antosiewicz, D. M.; Campbell, P.; Johnson, K. A.; McIntire, L. V. (Principal Investigator)

    1997-01-01

    Expression of the Arabidopsis TCH genes is markedly upregulated in response to a variety of environmental stimuli including the seemingly innocuous stimulus of touch. Understanding the mechanism(s) and factors that control TCH gene regulation will shed light on the signaling pathways that enable plants to respond to environmental conditions. The TCH proteins include calmodulin, calmodulin-related proteins and a xyloglucan endotransglycosylase. Expression analyses and localization of protein accumulation indicates that the potential sites of TCH protein function include expanding cells and tissues under mechanical strain. We hypothesize that at least a subset of the TCH proteins may collaborate in cell wall biogenesis.

  17. Response of present urban regulation conceptions to social environmental challenges in Belém (PA.

    Directory of Open Access Journals (Sweden)

    Ana Cláudia Duarte Cardoso

    2015-12-01

    Full Text Available This article discusses built form management of Brazilian cities, with the aim of evaluating the effectiveness of ordinary urban regulations applied to tackle social and environmental challenges experienced in two neighborhoods of Belém, Pará. Studied areas had thermal and acoustic measurements, which were associated to a survey with dwellers in order to qualify the human experience in these neighborhoods. Results show that a wider number of variables, than those already found in zoning and urban regulation, should be considered to obtain a more efficient microclimate control and to reduce dependency on energy and income for a better city experience.

  18. The community regulation for environmental management and audit: an opportunity for firms. Some Enea promotion actions

    International Nuclear Information System (INIS)

    Andriola, L.; Brunetti, N.; Caropreso, G.; Luciani, R.; Merelli, A.

    1999-01-01

    EMAS (Environmental Management and Audit Scheme), introduced by the 1836/93 Community regulation, is one of the tools activated by the European Union in the field of firm-environment interactions, to overcome the old Command and Control logic by means of the new Moral Suasion one. EMAS has a voluntary character: it intends to replace conflicting relations between control authority and firm with relations centred on a dialogue and action agreed upon by the parties, on the basis of impartial and reliable information. The report illustrates the procedure for applying this regulation, EMAS advantages for firms, its implementation in Italy and the most important pilot actions carried out by ENEA [it

  19. Genetic and environmental influences on individual differences in emotion regulation and its relation to working memory in toddlerhood.

    Science.gov (United States)

    Wang, Manjie; Saudino, Kimberly J

    2013-12-01

    This is the first study to explore genetic and environmental contributions to individual differences in emotion regulation in toddlers, and the first to examine the genetic and environmental etiology underlying the association between emotion regulation and working memory. In a sample of 304 same-sex twin pairs (140 MZ, 164 DZ) at age 3, emotion regulation was assessed using the Behavior Rating Scale of the Bayley Scales of Infant Development (BRS; Bayley, 1993), and working memory was measured by the visually cued recall (VCR) task (Zelazo, Jacques, Burack, & Frye, 2002) and several memory tasks from the Mental Scale of the BSID. Based on model-fitting analyses, both emotion regulation and working memory were significantly influenced by genetic and nonshared environmental factors. Shared environmental effects were significant for working memory, but not for emotion regulation. Only genetic factors significantly contributed to the covariation between emotion regulation and working memory.

  20. The Fit Between the UK Environmental Information Regulations and the Freedom of Information Act

    Directory of Open Access Journals (Sweden)

    Colin Pelton

    2008-08-01

    Full Text Available The Natural Environment Research Council (NERC is one of seven UK Research Councils. It delivers independent research, survey, training and knowledge transfer in the environmental sciences. All the UK Research Councils are public bodies falling under the Freedom of Information Act 2000 and the Environmental Information Regulations 2004. This open access legislation came into force on January 1, 2005 and since then the authors have built up substantial experience in managing NERC’s data and information under both the Act and the Regulations. This article aims to explain how to manage the, often blurred, boundary between these two pieces of legislation, and the overlap between data management and the legislation.

  1. Impacts of new environmental and safety regulations on uranium mining, milling and waste management in China

    International Nuclear Information System (INIS)

    Wang Yongping; Zheng Yuhui; Shi Xiangjun

    2001-01-01

    Nuclear power progress has triggered the development and innovation of nuclear fuel industries in China. At present the Chinese government has put more emphasis on industrial readjustment and technical innovation in uranium mining and milling in order to fuel the nuclear power development, satisfy environmental protection and improve economic efficiency of the industry. The current organizations and approval procedure for establishing regulations and the implementation and consequences of the regulations, technical polices and development strategies concerning uranium mining, milling, treatment of waste ores and mill tailings, and reduction of the workers' suffered exposure dose etc. in China are discussed and the economic, health and environmental impacts of the uranium mining and metallurgy with reformation achievement and the introduction of advanced technologies such as the in-situ leaching and heap leaching mining technologies are assessed in this paper. (author)

  2. The economic value of the flow regulation environmental service in a Brazilian urban watershed

    Science.gov (United States)

    Marques, Guilherme F.; de Souza, Verônica B. F. S.; Moraes, Natália V.

    2017-11-01

    Urban flood management have often focused either on the capacity expansion of drainage systems or on artificial detention storage. While flood control should take part early on urban planning, not enough is known to guide such plans and provide incentive to land use decisions that minimize the vulnerability to localized floods. In this paper, we offer a broader perspective on flood protection, by treating the original hydrologic flow regulation as an environmental service, and exploring how the value of this environmental service drives economic land use decisions that convert original (permeable) land into urbanized (impermeable). We investigate the relationship between land use decisions and their hydrologic consequences explicitly, and use this relationship to simulate resulting land use scenarios depending on the value attached to the environmental service of flow regulation. Rainfall-runoff simulation model results are combined to an optimization model based on two-stage stochastic programming approach to model economic land use decisions. The objective function maximizes the total expected land use benefit in an urban area, considering the opportunity cost of permeable areas in the first stage and the resulting loss of the environmental service of flow regulation on the second stage, under several probable hydrological events. A watershed in the city of Belo Horizonte, Brazil, is used to demonstrate the approach. Different values attached to the environmental service were tested, from zero to higher than the opportunity cost of land, and artificial detention infrastructure was included to calculate the resulting land use change and the loss in the environmental service value. Results indicate that by valuing the environmental service loss and discounting it from the economic benefits of land use, alternative solutions to land use are found, with decreased peak flows and lower flood frequency. Combined solutions including structural and non

  3. Vulnerability of US thermoelectric power generation to climate change when incorporating state-level environmental regulations

    Science.gov (United States)

    Liu, Lu; Hejazi, Mohamad; Li, Hongyi; Forman, Barton; Zhang, Xiao

    2017-08-01

    Previous modelling studies suggest that thermoelectric power generation is vulnerable to climate change, whereas studies based on historical data suggest the impact will be less severe. Here we explore the vulnerability of thermoelectric power generation in the United States to climate change by coupling an Earth system model with a thermoelectric power generation model, including state-level representation of environmental regulations on thermal effluents. We find that the impact of climate change is lower than in previous modelling estimates due to an inclusion of a spatially disaggregated representation of environmental regulations and provisional variances that temporarily relieve power plants from permit requirements. More specifically, our results indicate that climate change alone may reduce average generating capacity by 2-3% by the 2060s, while reductions of up to 12% are expected if environmental requirements are enforced without waivers for thermal variation. Our work highlights the significance of accounting for legal constructs and underscores the effects of provisional variances in addition to environmental requirements.

  4. Short-term regulation of hydro powerplants. Studies on the environmental effects

    International Nuclear Information System (INIS)

    Sinisalmi, T.; Riihimaeki, J.; Vehanen, T.; Yrjaenae, T.

    1997-01-01

    The publication is a final report on a project studying effects of short-term regulation of hydro power plants. The project consists of two parts: (1) examining and developing methods for evaluation, (2) applying methods in a case study at the Oulujoki River. The economic value of short-term regulation was studied with a model consisting of an optimization model and a river simulation model. Constraints on water level or discharge variations could be given to the power plants and their economical influence could be studied. Effects on shoreline recreation use due to water level fluctuation were studied with a model where various effects are made commensurable and expressed in monetary terms. A literature survey and field experiments were used to study the methods for assessing effects of short-term regulation on river habitats. The state and development needs of fish stocks and fisheries in large regulated rivers were studied and an environmental classification was made. Remedial measures for the short-term regulated rivers were studied with a literature survey and enquiries. A comprehensive picture of the various effects of short-term regulation was gained in the case study in Oulujoki River (110 km long, 7 power plants). Harmful effects can be reduced with the given recommendations of remedial measures on environment and the usage of the hydro power plants. (orig.) 52 refs

  5. Short-term regulation of hydro powerplants. Studies on the environmental effects

    Energy Technology Data Exchange (ETDEWEB)

    Sinisalmi, T. [ed.; Forsius, J.; Muotka, J.; Soimakallio, H. [Imatran Voima Oy, Vantaa (Finland); Riihimaeki, J. [VTT, Espoo (Finland); Vehanen, T. [Finnish Game and Fisheries Research Inst. (Finland); Yrjaenae, T. [North Ostrobothnia Regional Environmental Centre, Oulu (Finland)

    1997-12-31

    The publication is a final report on a project studying effects of short-term regulation of hydro power plants. The project consists of two parts: (1) examining and developing methods for evaluation, (2) applying methods in a case study at the Oulujoki River. The economic value of short-term regulation was studied with a model consisting of an optimization model and a river simulation model. Constraints on water level or discharge variations could be given to the power plants and their economical influence could be studied. Effects on shoreline recreation use due to water level fluctuation were studied with a model where various effects are made commensurable and expressed in monetary terms. A literature survey and field experiments were used to study the methods for assessing effects of short-term regulation on river habitats. The state and development needs of fish stocks and fisheries in large regulated rivers were studied and an environmental classification was made. Remedial measures for the short-term regulated rivers were studied with a literature survey and enquiries. A comprehensive picture of the various effects of short-term regulation was gained in the case study in Oulujoki River (110 km long, 7 power plants). Harmful effects can be reduced with the given recommendations of remedial measures on environment and the usage of the hydro power plants. (orig.) 52 refs.

  6. Economic effects of environmental regulations on finding and developing crude oil in the U.S

    International Nuclear Information System (INIS)

    Godec, M.L.; Biglarbigi, K.

    1991-01-01

    A number of legislative and regulatory initiatives being considered to protect the environment could affect the economics of U.S. oil and gas E and P. This paper summarizes the results of a comprehensive assessment of the potential cumulative energy and economic impacts of some of these initiatives on U.S. crude oil supplies. The results of the analysis clearly demonstrate that increased environmental regulations on U.S. crude oil E and P can significantly affect ultimate crude oil recovery. The extent of regulations imposed will determine the level of impact, but significant effects could be felt over a wide range of regulations, crude oil prices, and levels of development of extraction technologies

  7. [Research advance in nitrogen metabolism of plant and its environmental regulation].

    Science.gov (United States)

    Xu, Zhenzhu; Zhou, Guangsheng

    2004-03-01

    Nitrogen metabolism is not only one of the basic processes of plant physiology, but also one of the important parts of global chemical cycle. Plant nitrogen assimilation directly takes part in the synthesis and conversion of amino acid through the reduction of nitrate. During this stage, some key enzymes, e.g., nitrate reductase (NR), glutamine synthetase (GS), glutamate dehydrogenase (GDH), glutamine synthase (GOGAT), aspargine synthetase (AS), and asparate aminotransferase (AspAT) participate these processes. The protein is assimilated in plant cell through amino acid, and becomes a part of plant organism through modifying, classifying, transporting and storing processes, etc. The nitrogen metabolism is associated with carbonic metabolism through key enzyme regulations and the conversion of products, which consists of basic life process. Among these amino acids in plant cell, glutamic acid (Glu), glutamine (Gln), aspartic acid (Asp) and asparagines (Asn), etc., play a key role, which regulates their conversion each other and their contents in the plant cell through regulating formation and activity of those key enzymes. Environmental factors also affect the conversion and recycle of the key amino acids through regulating gene expression of the key enzymes and their activities. Nitrate and light intensity positively regulate the gene transcription of NR, but ammonium ions and Glu, Gln do the negative way. Water deficit is a very serious constraint on N2 fixation rate and soybean (Glycine max Merr.) grain yield, in which, ureide accumulation and degradation under water deficit appear to be the key issues of feedback mechanism on nitrogen fixation. Water stress decreases NR activity, but increases proteinase activity, and thus, they regulate plant nitrogen metabolism, although there are some different effects among species and cultivars. Water stress also decreases plant tissue protein content, ratio of protein and amino acid, and reduces the absorption of amino

  8. jurisprudence precedent on the instruments of environmental regulation of the electrical colombian sector

    International Nuclear Information System (INIS)

    Arcila R, Jaime Leon; Velasquez A, Hector I

    2009-01-01

    What the authors of the Law of the Environment have named the green Constitution or the ecological Constitution of 1991, necessarily it has consequences in the legal practice of the instruments of environmental management in all the levels and sectors of the economy, especially if the previous thing is analyzed in the frame of the Social State of Law in the Constitution of 1991, under this perspective, it is possible to understand the emptiness and inconsistencies of the environmental management in the electrical Colombian sector (SEC), from the critical analysis of the instruments of environmental regulation established in the in the Law in addition it is possible to check these instruments in his role of tools for the environmental management, to identify a constitutional and legal conceptualization adapted for the development of the same ones and to determine the necessary adjustments to realize in his environmental role of management tools in the SEC. The attainment of the previous aims carries an own methodology of the social qualitative research in his juridical political levels. The content of this article realizes the first advances in order to study from a juriprudential and not merely legal optics, since up to the moment the topic has been approached.

  9. Benefits and disadvantages of self-regulation of environmental noise from military training

    Science.gov (United States)

    Luz, George A.

    2002-05-01

    In a 1981 Executive decision, the Administration's Office of Management and Budget (OMB) told the Environmental Protection Agency to end funding of the Office of Noise Abatement and Control (ONAC). This decision, coupled with a specific exemption for military equipment contained in the Noise Control Act of 1972, ensured that the military departments would be self-regulating in regard to noise. This self-regulation for noise stands in contrast to the external regulation of other pollutants, such as air and water emissions. Two possible disadvantages of self-regulation are (1) reduced funding for noise management compared with funding for externally regulated pollutants, and (2) lack of an independent and external set of standards for determining acceptable limits on community noise exposure. Three possible benefits are (1) avoiding the costs of mitigating trivial violations of external standards, (2) maintaining a long-standing policy of preventing noise problems through land use planning, and (3) enabling negotiated solutions between installations and their neighboring communities. The paper ends with an examination of a negotiated solution for a community subjected to noise from the detonation of obsolete ammunition.

  10. Environmental regulation of leaf colour in red 35S:PAP1 Arabidopsis thaliana.

    Science.gov (United States)

    Rowan, Daryl D; Cao, Mingshu; Lin-Wang, Kui; Cooney, Janine M; Jensen, Dwayne J; Austin, Paul T; Hunt, Martin B; Norling, Cara; Hellens, Roger P; Schaffer, Robert J; Allan, Andrew C

    2009-01-01

    * High-temperature, low-light (HTLL) treatment of 35S:PAP1 Arabidopsis thaliana over-expressing the PAP1 (Production of Anthocyanin Pigment 1) gene results in reversible reduction of red colouration, suggesting the action of additional anthocyanin regulators. High-performance liquid chromatography (HPLC), liquid chromatography mass spectrometry (LCMS) and Affimetrix-based microarrays were used to measure changes in anthocyanin, flavonoids, and gene expression in response to HTLL. * HTLL treatment of control and 35S:PAP1 A. thaliana resulted in a reversible reduction in the concentrations of major anthocyanins despite ongoing over-expression of the PAP1 MYB transcription factor. Twenty-one anthocyanins including eight cis-coumaryl esters were identified by LCMS. The concentrations of nine anthocyanins were reduced and those of three were increased, consistent with a sequential process of anthocyanin degradation. Analysis of gene expression showed down-regulation of flavonol and anthocyanin biosynthesis and of transport-related genes within 24 h of HTLL treatment. No catabolic genes up-regulated by HTLL were found. * Reductions in the concentrations of anthocyanins and down-regulation of the genes of anthocyanin biosynthesis were achieved by environmental manipulation, despite ongoing over-expression of PAP1. Quantitative PCR showed reduced expression of three genes (TT8, TTG1 and EGL3) of the PAP1 transcriptional complex, and increased expression of the potential transcriptional repressors AtMYB3, AtMYB6 and AtMYBL2 coincided with HTLL-induced down-regulation of anthocyanin biosynthesis. * HTLL treatment offers a model system with which to explore anthocyanin catabolism and to discover novel genes involved in the environmental control of anthocyanins.

  11. Study on influence over approaching a market in the international trade by enhancing the international environmental regulation

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Sang In; Park, Joon Young [Korea Environment Institute, Seoul (Korea)

    1999-12-01

    The focal point of connecting trade and environment is what kind of influence over a national competitiveness of a national economy can be brought by enhancing environmental regulations. Traditionally it was accepted that the enhancement of environmental policy had a negative impact on competitiveness. However, recent study results show that the enhancement of environmental policy can strengthen industrial competitiveness for a long term. This study analyzes the significance of enhancing the international environmental regulation from a developing country's standpoint in association with this. 27 refs., 8 tabs.

  12. Bottom-up risk regulation? How nanotechnology risk knowledge gaps challenge federal and state environmental agencies.

    Science.gov (United States)

    Powell, Maria C; Griffin, Martin P A; Tai, Stephanie

    2008-09-01

    Nanotechnologies have been called the "Next Industrial Revolution." At the same time, scientists are raising concerns about the potential health and environmental risks related to the nano-sized materials used in nanotechnologies. Analyses suggest that current U.S. federal regulatory structures are not likely to adequately address these risks in a proactive manner. Given these trends, the premise of this paper is that state and local-level agencies will likely deal with many "end-of-pipe" issues as nanomaterials enter environmental media without prior toxicity testing, federal standards, or emissions controls. In this paper we (1) briefly describe potential environmental risks and benefits related to emerging nanotechnologies; (2) outline the capacities of the Toxic Substances Control Act, the Clean Air Act, the Clean Water Act, and the Resources Conservation and Recovery Act to address potential nanotechnology risks, and how risk data gaps challenge these regulations; (3) outline some of the key data gaps that challenge state-level regulatory capacities to address nanotechnologies' potential risks, using Wisconsin as a case study; and (4) discuss advantages and disadvantages of state versus federal approaches to nanotechnology risk regulation. In summary, we suggest some ways government agencies can be better prepared to address nanotechnology risk knowledge gaps and risk management.

  13. Workshop on environmental assessment. [Regulation of applications of nuclear energy and related ancillary systems

    Energy Technology Data Exchange (ETDEWEB)

    Watson, E.C. (comp.)

    1982-07-01

    Objectives of the workshop were: to review and evaluate the state-of-the-art of environmental impact assessments as applied to the regulation of applications of nuclear energy and related ancillary systems; to identify areas where existing technology allows establishing acceptable methods or standard practices that will meet the requirements of the NRC regulations, standards and guides for both normal operations and off-standard conditions including accident considerations; to illuminate topics where existing models or analytical methods are deficient because of unverified assumptions, a paucity of empirical data, conflicting results reported in the literature or a need for observation of operation systems; to compile, analyze and synthesize a prioritized set of research needs to advance the state-of-the-art to the level which will meet all of the requirements of the Commission's regulations, standards and guides; and to develop bases for maintaining the core of regulatory guidance at the optimum level balancing technical capabilities with practical considerations of cost and value to the regulatory process. The discussion held in small group sessions on aquatic, atmospheric, and terrestrial pathways are presented. The following research needs were identified as common to all three groups: validation of models; characterization of source terms; development of screening techniques; basis for de minimis levels of contamination; and updating of objectives for environmental monitoring programs.

  14. Airborne PCDD/Fs in two e-waste recycling regions after stricter environmental regulations.

    Science.gov (United States)

    Zhang, Manwen; Feng, Guixian; Yin, Wenhua; Xie, Bing; Ren, Mingzhong; Xu, Zhencheng; Zhang, Sukun; Cai, Zongwei

    2017-12-01

    Since the 2010s, the authorities of Guangdong province and local governments have enhanced law enforcement and environmental regulations to abolish open burning, acid washing, and other uncontrolled e-waste recycling activities. In this study, ambient air and indoor dust near different kinds of e-waste recycling processes were collected in Guiyu and Qingyuan to investigate the pollution status of particles and polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) after stricter environmental regulations. PM 2.5 and PCDD/Fs both showed significantly reduced levels in the two regions compared with the documented data. The congener distribution and principal component analysis results also confirmed the significant differences between the current PCDD/Fs pollution characterizations and the historical ones. The estimated total intake doses via air inhalation and dust ingestion of children in the recycling region of Guiyu ranged from 10 to 32pgTEQ/(kg•day), which far exceeded the tolerable daily intake (TDI) limit (1-4pgTEQ/(kg•day). Although the measurements showed a significant reduction of the release of PCDD/Fs, the pollution status was still considered severe in Guiyu town after stricter regulations were implemented. Copyright © 2017. Published by Elsevier B.V.

  15. Can green consumerism replace environmental regulation? A differentiated-products example

    Energy Technology Data Exchange (ETDEWEB)

    Eriksson, Clas [Department of Economics, Swedish University of Agricultural Sciences, P.O. Box 7013, S-750 07 Uppsala (Sweden)

    2004-09-01

    This paper assumes that consumers are willing to pay an extra premium for a good if it has a low impact on the environment. We examine if a little dose of such idealistic behavior has a large impact on the market equilibrium, and to what extent it can replace the environmental regulation. The analysis is carried out in a model with product differentiation, where consumers differ in their preferences for product quality. Consumers' willingness to pay the environmental premium may be uniformly or non-uniformly distributed. Green consumerism will only be modestly influential in both cases, despite the fact that product differentiation leads to relaxed competition and increased profits, and thereby creates leverage.

  16. Can green consumerism replace environmental regulation? A differentiated-products example

    International Nuclear Information System (INIS)

    Eriksson, Clas

    2004-01-01

    This paper assumes that consumers are willing to pay an extra premium for a good if it has a low impact on the environment. We examine if a little dose of such idealistic behavior has a large impact on the market equilibrium, and to what extent it can replace the environmental regulation. The analysis is carried out in a model with product differentiation, where consumers differ in their preferences for product quality. Consumers' willingness to pay the environmental premium may be uniformly or non-uniformly distributed. Green consumerism will only be modestly influential in both cases, despite the fact that product differentiation leads to relaxed competition and increased profits, and thereby creates leverage

  17. Green Taxation in Question: Politics and Economic Efficiency in Environmental Regulation

    DEFF Research Database (Denmark)

    Daugbjerg, Carsten; Svendsen, Gert Tinggaard

    Environmental economists have in general paid little or no attention to the political context within which green taxation would be introduced. In order to understand the real-life politics of green taxation, it is necessary to establish which political constraints determine the actual design...... of green taxes. Daugbjerg and Svendsen identify rent-seeking, party politics, and policy networks as the three main constraints in environmental regulation. This analysis forms the basis of policy recommendations on the future design of green taxation and international permit trading. Even though...... these policy recommendations are second best in strict economic terms, they are the best economic designs given that they must be politically feasible. Understanding the politics of green taxation is the prerequisite for the development of effective green taxation models which have a chance of being...

  18. Are environmental regulations keeping up with innovation? A case study of the nanotechnology industry.

    Science.gov (United States)

    Fairbrother, Anne; Fairbrother, Jennifer R

    2009-07-01

    Manufactured nanomaterials entered the marketplace of consumer goods in the mid-1990s. With the exception of pending reporting requirements in Canada, no new regulatory requirements have been imposed on the manufacture or use of nanomaterials or their commercial products, although in the past three years governments, industry, and nongovernmental organizations have questioned the need for new regulatory approaches. The debate hinges on whether current scientific information is sufficient for making risk-based decisions, if nanomaterial effects differ from macroscale products, and how much knowledge about potential risk governments should require before products are brought to market. The debate over when and how to regulate manufactured nanomaterials opens the door for a renewed discussion on regulatory environmental policy and suggests that the public may be demanding increased precaution and assurances from government. How government, in concert with industry and the open market, responds will set the bar for future regulations of emerging technologies.

  19. The impact of environmental regulations on United States crude oil supplies

    International Nuclear Information System (INIS)

    Godec, M.L.; Biglarbigi, K.

    1991-01-01

    A number of legislative and regulatory initiatives being considered to protect the environment could affect the economics of oil and gas exploration and production (E and P) in the Unites States. This paper summarizes the results of a comprehensive assessment of the potential cumulative energy and economic impacts of environmental regulatory initiatives on United States crude oil supplies. The results of the analysis clearly will determine the level of impact, but the results show that significant impacts are felt over a wide range of regulations, over a wide range of crude oil prices, and at two levels of development for extraction technologies. The regulations evaluated all have an impact on all resource categories analyzed in the study

  20. Corruption in the commons: why bribery hampers enforcement of environmental regulations in South African fisheries

    Directory of Open Access Journals (Sweden)

    Aksel Sundström

    2013-08-01

    Full Text Available Few studies have explored on the micro-level why corruption hampers environmental regulations. The relationship between corruption and regulatory compliance is here investigated through confidential in-depth interviews with South African small-scale fishermen. Respondents describe how the expected behavior of inspectors and other resource users to ask for or accept bribes are vital in their compliance decisions. The interviews also shed some light on the puzzling role of trust and trustworthiness of public officials. While resource users often knows inspectors personally – and uphold discretion necessary for bribery to continue – they depict them as dishonest and describe how corrupt acts decrease their trustworthiness. The findings from the South African case illustrate the importance of curbing both grand and petty corruption to increase the effectiveness of regulations in natural resource management.

  1. A study on environmental regulation and public inquiry system of nuclear facilities

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang Hun [Korea Association for Nuclear Technology, Taejon (Korea, Republic of); Kang, Chang Sun; Son, Ki Yon; Cho, Young Ho; Yang, Ji Won; Lee, Young Wook; Ko, Hyun Suk [Seoul National Univ., Seoul (Korea, Republic of)

    2000-03-15

    Public hearing system for domestic and foreign nuclear facilities are investigated and analyzed. As a result, Korean public hearing system are developed. Atomic Energy Act, Environmental Impact Assessment Act and Administrative Procedure Act of Korea are reviewed and appropriate acts, regulations, procedures and mandates of foreign countries including U.S.A are reviewed and analyzed. On the basis of these results the role of device to collect public opinion is identified for nuclear facility of Korea and the elementary principle of the system and recommendations are developed.

  2. Epigenetic Regulation of Centromere Chromatin Stability by Dietary and Environmental Factors.

    Science.gov (United States)

    Hernández-Saavedra, Diego; Strakovsky, Rita S; Ostrosky-Wegman, Patricia; Pan, Yuan-Xiang

    2017-11-01

    The centromere is a genomic locus required for the segregation of the chromosomes during cell division. This chromosomal region together with pericentromeres has been found to be susceptible to damage, and thus the perturbation of the centromere could lead to the development of aneuploidic events. Metabolic abnormalities that underlie the generation of cancer include inflammation, oxidative stress, cell cycle deregulation, and numerous others. The micronucleus assay, an early clinical marker of cancer, has been shown to provide a reliable measure of genotoxic damage that may signal cancer initiation. In the current review, we will discuss the events that lead to micronucleus formation and centromeric and pericentromeric chromatin instability, as well transcripts emanating from these regions, which were previously thought to be inactive. Studies were selected in PubMed if they reported the effects of nutritional status (macro- and micronutrients) or environmental toxicant exposure on micronucleus frequency or any other chromosomal abnormality in humans, animals, or cell models. Mounting evidence from epidemiologic, environmental, and nutritional studies provides a novel perspective on the origination of aneuploidic events. Although substantial evidence exists describing the role that nutritional status and environmental toxicants have on the generation of micronuclei and other nuclear aberrations, limited information is available to describe the importance of macro- and micronutrients on centromeric and pericentromeric chromatin stability. Moving forward, studies that specifically address the direct link between nutritional status, excess, or deficiency and the epigenetic regulation of the centromere will provide much needed insight into the nutritional and environmental regulation of this chromosomal region and the initiation of aneuploidy. © 2017 American Society for Nutrition.

  3. Identification and Transcription Profiling of NDUFS8 in Aedes taeniorhynchus (Diptera: Culicidae): Developmental Regulation and Environmental Response

    Science.gov (United States)

    2014-12-18

    Identification and transcription profiling of NDUFS8 in Aedes taeniorhynchus ( Diptera : Culicidae): developmental regulation and environmental response...mtDNA-encoded ND6 gene mutation.14 Aedes taeniorhynchus Wiedemann, a nuisance species, has attracted much attention recently.9,15–20 The aim of...taeniorhynchus ( Diptera : Culicidae): Developmental Regulation and Environmental Response 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER

  4. Stringent Expression Control of Pathogenic R-body Production in Legume Symbiont Azorhizobium caulinodans

    Directory of Open Access Journals (Sweden)

    Jun-ichi Matsuoka

    2017-07-01

    Full Text Available R bodies are insoluble large polymers consisting of small proteins encoded by reb genes and are coiled into cylindrical structures in bacterial cells. They were first discovered in Caedibacter species, which are obligate endosymbionts of paramecia. Caedibacter confers a killer trait on the host paramecia. R-body-producing symbionts are released from their host paramecia and kill symbiont-free paramecia after ingestion. The roles of R bodies have not been explained in bacteria other than Caedibacter. Azorhizobium caulinodans ORS571, a microsymbiont of the legume Sesbania rostrata, carries a reb operon containing four reb genes that are regulated by the repressor PraR. Herein, deletion of the praR gene resulted in R-body formation and death of host plant cells. The rebR gene in the reb operon encodes an activator. Three PraR binding sites and a RebR binding site are present in the promoter region of the reb operon. Expression analyses using strains with mutations within the PraR binding site and/or the RebR binding site revealed that PraR and RebR directly control the expression of the reb operon and that PraR dominantly represses reb expression. Furthermore, we found that the reb operon is highly expressed at low temperatures and that 2-oxoglutarate induces the expression of the reb operon by inhibiting PraR binding to the reb promoter. We conclude that R bodies are toxic not only in paramecium symbiosis but also in relationships between other bacteria and eukaryotic cells and that R-body formation is controlled by environmental factors.

  5. Does dishonesty really invite third-party punishment? Results of a more stringent test.

    Science.gov (United States)

    Konishi, Naoki; Ohtsubo, Yohsuke

    2015-05-01

    Many experiments have demonstrated that people are willing to incur cost to punish norm violators even when they are not directly harmed by the violation. Such altruistic third-party punishment is often considered an evolutionary underpinning of large-scale human cooperation. However, some scholars argue that previously demonstrated altruistic third-party punishment against fairness-norm violations may be an experimental artefact. For example, envy-driven retaliatory behaviour (i.e. spite) towards better-off unfair game players may be misidentified as altruistic punishment. Indeed, a recent experiment demonstrated that participants ceased to inflict third-party punishment against an unfair player once a series of key methodological problems were systematically controlled for. Noticing that a previous finding regarding apparently altruistic third-party punishment against honesty-norm violations may have been subject to methodological issues, we used a different and what we consider to be a more sound design to evaluate these findings. Third-party punishment against dishonest players withstood this more stringent test. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  6. Bulk development and stringent selection of microsatellite markers in the western flower thrips Frankliniella occidentalis.

    Science.gov (United States)

    Cao, Li-Jun; Li, Ze-Min; Wang, Ze-Hua; Zhu, Liang; Gong, Ya-Jun; Chen, Min; Wei, Shu-Jun

    2016-05-20

    Recent improvements in next-generation sequencing technologies have enabled investigation of microsatellites on a genome-wide scale. Faced with a huge amount of candidates, the use of appropriate marker selection criteria is crucial. Here, we used the western flower thrips Frankliniella occidentalis for an empirical microsatellite survey and validation; 132,251 candidate microsatellites were identified, 92,102 of which were perfect. Dinucleotides were the most abundant category, while (AG)n was the most abundant motif. Sixty primer pairs were designed and validated in two natural populations, of which 30 loci were polymorphic, stable, and repeatable, but not all in Hardy-Weinberg equilibrium (HWE) and linkage equilibrium. Four marker panels were constructed to understand effect of marker selection on population genetic analyses: (i) only accept loci with single nucleotide insertions (SNI); (ii) only accept the most polymorphic loci (MP); (iii) only accept loci that did not deviate from HWE, did not show SNIs, and had unambiguous peaks (SS) and (iv) all developed markers (ALL). Although the MP panel resulted in microsatellites of highest genetic diversity followed by the SNI, the SS performed best in individual assignment. Our study proposes stringent criteria for selection of microsatellites from a large-scale number of genomic candidates for population genetic studies.

  7. Regulations and decisions in environmental impact assessment of residues radioactivity content

    International Nuclear Information System (INIS)

    Santos, Adir Janete Godoy dos

    2005-01-01

    Surveillance of natural radionuclides in the environment did not have high priority over many years compared to that of man-made radioactivity. There is, however, an increasing interest in such measurements since enhanced exposure to natural radioactivity is receiving the same legal weight as any other radiation exposure. In this context the surveillance of technologically enhanced naturally occurring materials, called TENORM becomes important. In Brazil, the industries of processing and chemical compounds production were developed based on mining, milling, transformation and manufacture of ores from sedimentary origin, ignea or metamorphic, which must determine the radioactive composition of the generated solid wastes and residues. Many solids residues stored in the environment has been of environmental concern facing the industries and environmentalists in Brazil as it presents a potential threat to the surrounding environment and to individuals occupationally exposed. Radiation protection regulations have not been applied yet to these industries, as the Brazilian regulatory agency (Comissao Nacional de Energia Nuclear - CNEN) has only recently published a regulatory guide concerning mining and milling of naturally occurring radioactive materials, which may generate enhanced concentrations of radionuclides. With respect to external and internal exposure to natural radionuclides from the solid residues storage, the nuclides of 232 Th, 235 U and 238 U decay chains are relevant, due to the exposure of workers as well as of members of the public. Radionuclides released from a source can be present as ions, molecules, complexes, mononuclear or polynuclear species, colloids, pseudocolloids, particles or fragments varying in size (nominal molecular mass), structure, morphology, density, valence and charge properties. One of the main points in environmental impact assessment is to identify whether the chemical availability is under influence of these speciation

  8. NEAT--non-exercise activity thermogenesis--egocentric & geocentric environmental factors vs. biological regulation.

    Science.gov (United States)

    Levine, J A; Kotz, C M

    2005-08-01

    Non-exercise activity thermogenesis (NEAT) is the energy expenditure of all physical activities other than volitional sporting-like exercise. NEAT includes all those activities that render us vibrant, unique and independent beings such as going to work, playing guitar, toe-tapping and dancing. The factors that account for the 2000 kcal day(-1) variability of NEAT can be categorized as environmental or biological. The environmental determinants of NEAT can be view using one of two models. In the egocentric model we consider a single person as the focus, e.g. 'my job'. In the geocentric model we consider the 'environment' as the focus, e.g. well-lit and safe walk ways. These models provide us with a theoretical framework to understand NEAT and how best to intervene to promote NEAT. As well as environmental effectors of NEAT, there are also biological regulatory mechanisms that enable us to account for three-quarters of the biological variance in susceptibility and resistance to fat gain with human over-feeding. NEAT is likely to be regulated through a central mechanism that integrates NEAT with energy intake and energy stores so that NEAT is activated with over-feeding and suppressed with under-feeding. In conclusion, NEAT is likely to serve as a crucial thermoregulatory switch between energy storage and dissipation that is biologically regulated and influenced, and perhaps over-ridden, by environment. Deciphering the role of NEAT may lead to a better understanding of the pathogenesis, prevention and treatment of obesity.

  9. Vulnerability of US thermoelectric power generation to climate change when incorporating state-level environmental regulations

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Lu; Hejazi, Mohamad; Li, Hongyi; Forman, Barton; Zhang, Xiao

    2017-07-10

    This study explores the interactions between climate and thermoelectric generation in the U.S. by coupling an Earth System Model with a thermoelectric power generation model. We validated model simulations of power production for selected power plants (~44% of existing thermoelectric capacity) against reported values. In addition, we projected future usable capacity for existing power plants under two different climate change scenarios. Results indicate that climate change alone may reduce average thermoelectric generating capacity by 2%-3% by the 2060s. Reductions up to 12% are expected if environmental requirements are enforced without waivers for thermal variation. This study concludes that the impact of climate change on the U.S. thermoelectric power system is less than previous estimates due to an inclusion of a spatially-disaggregated representation of environmental regulations and provisional variances that temporarily relieve power plants from permit requirements. This work highlights the significance of accounting for legal constructs in which the operation of power plants are managed, and underscores the effects of provisional variances in addition to environmental requirements.

  10. Nanotechnology research and regulation: A plan to ensure human and environmental safety

    Science.gov (United States)

    Reddy, Anitha

    The influence of nanotechnology spans numerous fields and is increasing rapidly due to the financial and research contributions to the field. The impact of nanotechnologybased products on human health and the environment is far from being understood. Research output related to environmental, health, and safety issues is too slow and far behind developments to address the vast number of types of nanoparticles and new uses being discovered. This thesis summarizes nanotechnology related regulations, applications, and current research related to environmental and human toxicity in order to put into perspective the gaping holes existing in the safe production, use, and disposal of nanotechnology. There were a number of conclusions that were determined following the literature survey of this thesis. There is currently a lack of international cooperation between regulatory agencies and research institutions who are involved with nanotechnology. The only entities that have made regulatory progress include the United States, European Union, and Australia. The toxicological impacts of nanotechnology are not fully understood due to the dearth of research, as well as the absence of testing and measuring infrastructure. Chapter 6 of this thesis proposes an effective and specific research strategy to expedite the creation of enforceable regulations in order to protect the environment, workers, and general public based on the conclusions described in the paragraph above. The strategy outlines the need for the development of an interagency committee, precationary limits, nanomaterial tracer system, nanomaterial data gathering, priority list, funds for toxicity research, and open database to information and materials. The aspects of the outline strategy will ensure the successful and efficient regulation of nanotechnology.

  11. Appetite self-regulation: Environmental and policy influences on eating behaviors.

    Science.gov (United States)

    Schwartz, Marlene B; Just, David R; Chriqui, Jamie F; Ammerman, Alice S

    2017-03-01

    Appetite regulation is influenced by the environment, and the environment is shaped by food-related policies. This review summarizes the environment and policy research portion of an NIH Workshop (Bethesda, MD, 2015) titled "Self-Regulation of Appetite-It's Complicated." In this paper, we begin by making the case for why policy is an important tool in efforts to improve nutrition, and we introduce an ecological framework that illustrates the multiple layers that influence what people eat. We describe the state of the science on how policies influence behavior in several key areas: the federal food programs, schools, child care, food and beverage pricing, marketing to youth, behavioral economics, and changing defaults. Next, we propose novel approaches for multidisciplinary prevention and intervention strategies to promote breastfeeding, and examine interactions between psychology and the environment. Policy and environmental change are the most distal influences on individual-level appetite regulation, yet these strategies can reach many people at once by changing the environment in which food choices are made. We note the need for more research to understand compensatory behavior, reactance, and how to effectively change social norms. To move forward, we need a more sophisticated understanding of how individual psychological and biological factors interact with the environment and policy influences. © 2017 The Obesity Society.

  12. The rapidly evolving centromere-specific histone has stringent functional requirements in Arabidopsis thaliana.

    Science.gov (United States)

    Ravi, Maruthachalam; Kwong, Pak N; Menorca, Ron M G; Valencia, Joel T; Ramahi, Joseph S; Stewart, Jodi L; Tran, Robert K; Sundaresan, Venkatesan; Comai, Luca; Chan, Simon W-L

    2010-10-01

    Centromeres control chromosome inheritance in eukaryotes, yet their DNA structure and primary sequence are hypervariable. Most animals and plants have megabases of tandem repeats at their centromeres, unlike yeast with unique centromere sequences. Centromere function requires the centromere-specific histone CENH3 (CENP-A in human), which replaces histone H3 in centromeric nucleosomes. CENH3 evolves rapidly, particularly in its N-terminal tail domain. A portion of the CENH3 histone-fold domain, the CENP-A targeting domain (CATD), has been previously shown to confer kinetochore localization and centromere function when swapped into human H3. Furthermore, CENP-A in human cells can be functionally replaced by CENH3 from distantly related organisms including Saccharomyces cerevisiae. We have used cenh3-1 (a null mutant in Arabidopsis thaliana) to replace endogenous CENH3 with GFP-tagged variants. A H3.3 tail domain-CENH3 histone-fold domain chimera rescued viability of cenh3-1, but CENH3's lacking a tail domain were nonfunctional. In contrast to human results, H3 containing the A. thaliana CATD cannot complement cenh3-1. GFP-CENH3 from the sister species A. arenosa functionally replaces A. thaliana CENH3. GFP-CENH3 from the close relative Brassica rapa was targeted to centromeres, but did not complement cenh3-1, indicating that kinetochore localization and centromere function can be uncoupled. We conclude that CENH3 function in A. thaliana, an organism with large tandem repeat centromeres, has stringent requirements for functional complementation in mitosis.

  13. Inferences on the biochemical and environmental regulation of universal stress proteins from Schistosomiasis parasites

    Directory of Open Access Journals (Sweden)

    Mbah AN

    2013-05-01

    Full Text Available Andreas N Mbah,1,2 Ousman Mahmud,1 Omotayo R Awofolu,2 Raphael D Isokpehi11Center for Bioinformatics and Computational Biology, Department of Biology, Jackson State University, Jackson, MS, USA; 2Department of Environmental Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Pretoria, South AfricaBackground: Human schistosomiasis is a freshwater snail-transmitted disease caused by parasitic flatworms of the Schistosoma genus. Schistosoma haematobium, Schistosoma mansoni, and Schistosoma japonicum are the three major species infecting humans. These parasites undergo a complex developmental life cycle, in which they encounter a plethora of environmental signals. The presence of genes encoding the universal stress protein (USP domain in the genomes of Schistosoma spp. suggests these flatworms are equipped to respond to unfavorable conditions. Though data on gene expression is available for USP genes, their biochemical and environmental regulation are incompletely understood. The identification of additional regulatory molecules for Schistosoma. USPs, which may be present in the human, snail, or water environments, could also be useful for schistosomiasis interventions.Methods: We developed a protocol that includes a visual analytics stage to facilitate integration, visualization, and decision making, from the results of sequence analyses and data collection on a set of 13 USPs from S. mansoni and S. japonicum.Results: Multiple sequence alignment identified conserved sites that could be key residues regulating the function of USPs of the Schistosoma spp. Based on the consistency and completeness of sequence annotation, we prioritized for further research the gene for a 184-amino-acid-long USP that is present in the genomes of the three human-infecting Schistosoma spp. Calcium, zinc, and magnesium ions were predicted to interact with the protein product of the gene.Conclusion: Given that the initial effects of

  14. Inferences on the biochemical and environmental regulation of universal stress proteins from Schistosomiasis parasites

    Science.gov (United States)

    Mbah, Andreas N; Mahmud, Ousman; Awofolu, Omotayo R; Isokpehi, Raphael D

    2013-01-01

    Background Human schistosomiasis is a freshwater snail-transmitted disease caused by parasitic flatworms of the Schistosoma genus. Schistosoma haematobium, Schistosoma mansoni, and Schistosoma japonicum are the three major species infecting humans. These parasites undergo a complex developmental life cycle, in which they encounter a plethora of environmental signals. The presence of genes encoding the universal stress protein (USP) domain in the genomes of Schistosoma spp. suggests these flatworms are equipped to respond to unfavorable conditions. Though data on gene expression is available for USP genes, their biochemical and environmental regulation are incompletely understood. The identification of additional regulatory molecules for Schistosoma. USPs, which may be present in the human, snail, or water environments, could also be useful for schistosomiasis interventions. Methods We developed a protocol that includes a visual analytics stage to facilitate integration, visualization, and decision making, from the results of sequence analyses and data collection on a set of 13 USPs from S. mansoni and S. japonicum. Results Multiple sequence alignment identified conserved sites that could be key residues regulating the function of USPs of the Schistosoma spp. Based on the consistency and completeness of sequence annotation, we prioritized for further research the gene for a 184-amino-acid-long USP that is present in the genomes of the three human-infecting Schistosoma spp. Calcium, zinc, and magnesium ions were predicted to interact with the protein product of the gene. Conclusion Given that the initial effects of praziquantel on schistosomes include the influx of calcium ions, additional investigations are required to (1) functionally characterize the interactions of calcium ions with the amino acid residues of Schistosoma USPs; and (2) determine the transcriptional response of Schistosoma. USP genes to praziquantel. The data sets produced, and the visual analytics

  15. Environmental oxygen tension regulates the energy metabolism and self-renewal of human embryonic stem cells.

    Science.gov (United States)

    Forristal, Catherine E; Christensen, David R; Chinnery, Fay E; Petruzzelli, Raffaella; Parry, Kate L; Sanchez-Elsner, Tilman; Houghton, Franchesca D

    2013-01-01

    Energy metabolism is intrinsic to cell viability but surprisingly has been little studied in human embryonic stem cells (hESCs). The current study aims to investigate the effect of environmental O2 tension on carbohydrate utilisation of hESCs. Highly pluripotent hESCs cultured at 5% O2 consumed significantly more glucose, less pyruvate and produced more lactate compared to those maintained at 20% O2. Moreover, hESCs cultured at atmospheric O2 levels expressed significantly less OCT4, SOX2 and NANOG than those maintained at 5% O2. To determine whether this difference in metabolism was a reflection of the pluripotent state, hESCs were cultured at 5% O2 in the absence of FGF2 for 16 hours leading to a significant reduction in the expression of SOX2. In addition, these cells consumed less glucose and produced significantly less lactate compared to those cultured in the presence of FGF2. hESCs maintained at 5% O2 were found to consume significantly less O2 than those cultured in the absence of FGF2, or at 20% O2. GLUT1 expression correlated with glucose consumption and using siRNA and chromatin immunoprecipitation was found to be directly regulated by hypoxia inducible factor (HIF)-2α at 5% O2. In conclusion, highly pluripotent cells associated with hypoxic culture consume low levels of O2, high levels of glucose and produce large amounts of lactate, while at atmospheric conditions glucose consumption and lactate production are reduced and there is an increase in oxidative metabolism. These data suggest that environmental O2 regulates energy metabolism and is intrinsic to the self-renewal of hESCs.

  16. Environmental Regulations on Waste Electrical Equipment Industry: The Production Chain to the Final Consumer

    Directory of Open Access Journals (Sweden)

    Marilia Tunes Mazon

    2012-06-01

    Full Text Available The relevance of the electronics industry requires its transition to sustainable production patterns, as defined by the European directives WEEE, RoHS, and the National Policy on Solid Waste. In 2010, the group began a national project whose purpose is to support sustainability with a focus on the triple bottom line Brazilian electronics industry. The implementation of these proposals began with the implementation of a pilot project with nine companies of electromedical equipment, chosen because they are technology intensive, and require exporters suit environmental regulations. This paper aims to present the main results obtained in the studies with these nine companies in the period Apr/2011 Mar/2012 regarding the suitability of its products, processes, management systems and supply chains. The study was divided into three stages: an assessment to identify general aspects of each organization, a thorough assessment to understand the characteristics of each organization ahead of the general characteristics of the group analyzed and a detailed diagnosis, performed individually during visits in companies. The main findings were that the waste management and reverse logistics associated are still incipient, the products still have dangerous substances and supply chain is still very poorly prepared for the challenges. The level of employment of employees and costs associated with the adequacy of its products and processes, constitute the two biggest problems for companies fit the relevant environmental legislation.

  17. Challenges of the growing African cement market – environmental issues, regulative framework, and quality infrastructure requirements

    Directory of Open Access Journals (Sweden)

    Schmidt Wolfram

    2018-01-01

    Full Text Available The African cement, concrete and construction business is growing at rapid pace. The cement sales are expected to grow rapidly until 2050. The number of newly built cement plants increases dramatically and in addition more cements are being imported from outside the continent, e.g. from Turkey, Pakistan, Indonesia, and China, driven by overcapacities in the countries of origin. This causes a high number of potentials and challenges at the same time. Newly built cement plants can operate directly at best technological state of the art and thus incorporate more sustainable technologies as well as produce new and more sustainable products such as cements blended with sustainable supplementary cementitious materials such as calcined clays, and industrial or agricultural by products. At the same time the new variety of binding agent as well as the international imports, which are driven by price considerations, make the cement market prone to quality scatter. This puts pressure on the quality control regulations and institutions to ensure safety of construction, healthy application, and environmental safety for the population. The paper presents possible solutions to build up the rapidly increasing African cement production more sustainably than in the rest of the world as well as the related challenges and obstacles that need to be overcome. Based on experiences with a series of pan-African cement testing laboratory proficiency schemes conclusions are made on technical, regulative and political level.

  18. On the developmental and environmental regulation of secondary metabolism in Vaccinium spp. berries

    Directory of Open Access Journals (Sweden)

    Katja eKarppinen

    2016-05-01

    Full Text Available Secondary metabolites have important defense and signaling roles, and they contribute to the overall quality of developing and ripening fruits. Blueberries, bilberries, cranberries and other Vaccinium berries are fleshy berry fruits recognized for the high levels of bioactive compounds, especially anthocyanin pigments. Besides anthocyanins and other products of the phenylpropanoid and flavonoid pathways, these berries also contain other metabolites of interest, such as carotenoid derivatives, vitamins and flavor compounds. Recently, new information has been achieved on the mechanisms related with developmental, environmental and genetic factors involved in the regulation of secondary metabolism in Vaccinium fruits. Especially light conditions and temperature are demonstrated to have a prominent role on the composition of phenolic compounds. The present review focuses on the studies on mechanisms associated with the regulation of key secondary metabolites, mainly phenolic compounds, in Vaccinium berries. The advances in the research concerning biosynthesis of phenolic compounds in Vaccinium species, including specific studies with mutant genotypes in addition to controlled and field experiments on the genotype x environment (GxE interaction, are discussed. The recently published Vaccinium transcriptome and genome databases provide new tools for the studies on the metabolic routes.

  19. Reaction of simple sterile sugar beet hybrids to regulated environmental factors for sugar yield

    Directory of Open Access Journals (Sweden)

    М. О. Корнєєва

    2014-03-01

    Full Text Available Sugar yield, an important indicator, is resulting from interaction of two components: the yield and sugar content, both they are controlled by polygenes, and influenced significantly by environment. A.V. Kilchevskyi and L.V. Hotyliova pointed to the fact that in breeding, contrary to evolution, stabilizing forms are dominated by driving ones, which determine the growth response to regulated factors and decreased resistance to non-regulated environmental factors [1]. A relevant breeding trend is to create the genotypes adequate with certain technologies, so to say «low input variety high input variety» i.e. varieties with low and high energy contribution to technology. From this perspective, selection of stable in their manifestation lines against the analyzing backgrounds has become an important element of the breeding process [2]. Home scientists, such as A.L. Mazmulov and M.S. Hrytsyk have contributed greatly to the development and application of the agro-backgrounds [3, 4].

  20. The interaction of new environmental regulations and the financing of waste processing facilities

    International Nuclear Information System (INIS)

    Rowley, D.A.

    1991-01-01

    This paper will first explore new EPA regulations and how they are driving demand for environmental facilities. Special attention will be paid to the legal interaction of technology and federal and state policymaking. Attention also will be paid to the barriers to capital formation caused by federal regulation and the legal inadequacy of many infrastructure systems at the state and local level. Next, the paper will consider the implication of various financing techniques in light of these regulatory developments. Particular attention will be paid to existing legal and structural difficulties to the use of each of these three approaches, including tax incentives at the federal level, inability to use pollution control financing mechanisms in states, and the general decline of the availability of industrial revenue bond mechanisms. Finally, the paper will explore alternate credit support techniques that might be used to fill gaps between the regulatory pressures and the possible finance structures. It will examine possible uses of letters of credit, guarantees, forms of equity investment. Other, more difficult credit support devices such as insurance will be given brief consideration. Finally, there will be a brief overview of the liability implication for the various participants (debt inequity) in the financing of these facilities

  1. Stringently Defined Otitis Prone Children Demonstrate Deficient Naturally Induced Mucosal Antibody Response to Moraxella catarrhalis Proteins

    Directory of Open Access Journals (Sweden)

    Dabin Ren

    2017-08-01

    Full Text Available Moraxella catarrhalis (Mcat is a prominent mucosal pathogen causing acute otitis media (AOM. We studied Mcat nasopharyngeal (NP colonization, AOM frequency and mucosal antibody responses to four vaccine candidate Mcat proteins: outer membrane protein (OMP CD, oligopeptide permease (Opp A, hemagglutinin (Hag, and Pilin A clade 2 (PilA2 from stringently defined otitis prone (sOP children, who experience the greatest burden of disease, compared to non-otitis prone (NOP children. sOP children had higher NP colonization of Mcat (30 vs. 22%, P = 0.0003 and Mcat-caused AOM rates (49 vs. 24%, P < 0.0001 than NOP children. Natural acquisition of mucosal antibodies to Mcat proteins OMP CD (IgG, P < 0.0001, OppA (IgG, P = 0.018, Hag (IgG and IgA, both P < 0.0001, and PilA2 (IgA, P < 0.0001 was lower in sOP than NOP children. Higher levels of mucosal IgG to Hag (P = 0.039 and PilA2 (P = 0.0076, and IgA to OMP CD (P = 0.010, OppA (P = 0.030, and PilA2 (P = 0.043 were associated with lower carriage of Mcat in NOP but not sOP children. Higher levels of mucosal IgG to OMP CD (P = 0.0070 and Hag (P = 0.0003, and IgA to Hag (P = 0.0067 at asymptomatic colonization than those at onset of AOM were associated with significantly lower rate of Mcat NP colonization progressing to AOM in NOP compared to sOP children (3 vs. 26%, P < 0.0001. In conclusion, sOP children had a diminished mucosal antibody response to Mcat proteins, which was associated with higher frequencies of asymptomatic NP colonization and NP colonization progressing to Mcat-caused AOM. Enhancing Mcat antigen-specific mucosal immune responses to levels higher than achieved by natural exposure will be necessary to prevent AOM in sOP children.

  2. Role of the Stringent Stress Response in the Antibiotic Resistance Phenotype of Methicillin-Resistant Staphylococcus aureus.

    Science.gov (United States)

    Aedo, Sandra; Tomasz, Alexander

    2016-04-01

    Resistance to beta-lactam antibiotics in methicillin-resistantStaphylococcus aureus(MRSA) requires the presence of an acquired genetic determinant,mecAormecC, which encode penicillin-binding protein PBP2A or PBP2A', respectively. Although all MRSA strains share a mechanism of resistance, the phenotypic expression of beta-lactam resistance shows considerable strain-to-strain variation. The stringent stress response, a stress response that results from nutrient limitation, was shown to play a key role in determining the resistance level of an MRSA strain. In the present study, we validated the impact of the stringent stress response on transcription and translation ofmecAin the MRSA clinical isolate strain N315, which also carries known regulatory genes (mecI/mecR1/mecR2andblaI/blaR1) formecAtranscription. We showed that the impact of the stringent stress response on the resistance level may be restricted to beta-lactam resistance based on a "foreign" determinant such asmecA, as opposed to resistance based on mutations in the nativeS. aureusdeterminantpbpB(encoding PBP2). Our observations demonstrate that high-level resistance mediated by the stringent stress response follows the current model of beta-lactam resistance in which the native PBP2 protein is also essential for expression of the resistance phenotype. We also show that theStaphylococcus sciuri pbpDgene (also calledmecAI), the putative evolutionary precursor ofmecA, confers oxacillin resistance in anS. aureusstrain, generating a heterogeneous phenotype that can be converted to high and homogenous resistance by induction of the stringent stress response in the bacteria. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  3. Efficiency on execution of environmental regulations for hydroelectric enterprising; Eficiencia na execucao das normas ambientais para empreendimentos hidroeletricos

    Energy Technology Data Exchange (ETDEWEB)

    Nadaud, Gabriela Caiuby Ariani; Young, Carlos Eduardo Frickmann [Universidade Federal do Rio de Janeiro (IE/GEMA/UFRJ), RJ (Brazil). Inst. de Economia. Grupo de Economia do Meio Ambiente e do Desenvolvimento Sustentavel], E-mail: young@ie.ufrj.br

    2010-07-01

    Viewing a more efficiency in the accomplishment of environmental regulations related to hydroelectric enterprises, this paper presents a proposal for indexes which can help the enterprise. From the verification that the accomplishment of legal requests to obtain the licensing does not minimizes the conflict risks and the consequent expenses, this index methodology presents himself as an tool which allows more efficient compensation measurements and the consequent reduction of the social-environmental costs of the hydroelectric enterprises.

  4. Arabidopsis MADS-Box Transcription Factor AGL21 Acts as Environmental Surveillance of Seed Germination by Regulating ABI5 Expression.

    Science.gov (United States)

    Yu, Lin-Hui; Wu, Jie; Zhang, Zi-Sheng; Miao, Zi-Qing; Zhao, Ping-Xia; Wang, Zhen; Xiang, Cheng-Bin

    2017-06-05

    Seed germination is a crucial checkpoint for plant survival under unfavorable environmental conditions. Abscisic acid (ABA) signaling plays a vital role in integrating environmental information to regulate seed germination. It has been well known that MCM1/AGAMOUS/DEFICIENS/SRF (MADS)-box transcription factors are key regulators of seed and flower development in Arabidopsis. However, little is known about their functions in seed germination. Here we report that MADS-box transcription factor AGL21 is a negative regulator of seed germination and post-germination growth by controlling the expression of ABA-INSENSITIVE 5 (ABI5) in Arabidopsis. The AGL21-overexpressing plants were hypersensitive to ABA, salt, and osmotic stresses during seed germination and early post-germination growth, whereas agl21 mutants were less sensitive. We found that AGL21 positively regulated ABI5 expression in seeds. Consistently, genetic analyses showed that AGL21 is epistatic to ABI5 in controlling seed germination. Chromatin immunoprecipitation assays further demonstrated that AGL21 could directly bind to the ABI5 promoter in plant cells. Moreover, we found that AGL21 responded to multiple environmental stresses and plant hormones during seed germination. Taken together, our results suggest that AGL21 acts as a surveillance integrator that incorporates environmental cues and endogenous hormonal signals into ABA signaling to regulate seed germination and early post-germination growth. Copyright © 2017 The Author. Published by Elsevier Inc. All rights reserved.

  5. Response of an invasive native wetland plant to environmental flows: implications for managing regulated floodplain ecosystems.

    Science.gov (United States)

    Vivian, Lyndsey M; Marshall, David J; Godfree, Robert C

    2014-01-01

    The natural flow regimes of rivers underpin the health and function of floodplain ecosystems. However, infrastructure development and the over-extraction of water has led to the alteration of natural flow regimes, resulting in the degradation of river and floodplain habitats globally. In many catchments, including Australia's Murray-Darling Basin, environmental flows are seen as a potentially useful tool to restore natural flow regimes and manage the degradation of rivers and their associated floodplains. In this paper, we investigated whether environmental flows can assist in controlling an invasive native floodplain plant in Barmah Forest, south-eastern Australia. We experimentally quantified the effects of different environmental flow scenarios, including a shallow (20 cm) and deeper (50 cm) flood of different durations (12 and 20 weeks), as well as drought and soil-saturated conditions, on the growth and survival of seedlings of Juncus ingens, a native emergent macrophyte that has become invasive in some areas of Barmah Forest following river regulation and alteration of natural flow regimes. Three height classes of J. ingens (33 cm, 17 cm and 12 cm) were included in the experiment to explicitly test for relationships between treatments, plant survival and growth, and plant height. We found that seedling mortality occurred in the drought treatment and in the 20-week flood treatments of both depths; however, mortality rates in the flood treatments depended on initial plant height, with medium and short plants (initial heights of ≤17 cm) exhibiting the highest mortality rates. Both the 20 cm and 50 cm flood treatments of only 12 weeks duration were insufficient to cause mortality in any of the height classes; indeed, shoots of plants in the 20 cm flood treatment were able to elongate through the water surface at rapid rates. Our findings have important implications for management of Barmah Forest and floodplain ecosystems elsewhere, as it demonstrates

  6. Preliminary analysis of environmental regulations related to remedial action activities at the Oak Ridge National Laboratory: Environmental Sciences Division Publication No. 2695

    International Nuclear Information System (INIS)

    Voorhees, L.D.; Saylor, R.E.

    1986-11-01

    Past research and development activities at Oak Ridge National Laboratory (ORNL) have resulted in the presence of several areas where low-level radioactive and/or hazardous waste have been disposed of or that have been contaminated through accidental spills or planned releases of radionuclides. Although these areas have been monitored and controlled to ensure that on-site and off-site releases of contaminants are within applicable Department of Energy (DOE) guidelines, ORNL established the Environmental Restoration and Facilities Upgrade (ERFU) Program to address formally the immediate and long-range needs of meeting all applicable federal and state regulations regarding waste disposal. The environmental laws, regulations, and DOE Orders governing the cleanup activities are numerous and complex. Hence, a synthesis of the principal regulations related to the ERFU Program is presented to facilitate efficient planning for characterization and cleanup of contaminated sites. Because of regulatory decisions made after this report was finalized, several statements presented herein may no longer apply to the ERFU Program. Nevertheless, the report is issued as originally written so that ORNL's early planning efforts to comply with environmental laws and legislation are formally documented. Several general principles to consider when developing a plan for environmental compliance - which would be of use to others who must comply with legislation related to the cleanup of sites contaminated with radionuclides and hazardous chemicals - are also discussed

  7. Legal issues of the environmental safety regulation in the sphere of nanotechnology in Russian Federation

    International Nuclear Information System (INIS)

    Belokrylova, Ekaterina A

    2013-01-01

    Nowadays one of the principal innovative spheres in Russia is considered to be a rapid development of nanotechnology and nanomaterials and implementation its products into almost all fields of social and industrial life. Nevertheless, despite the pointed advantages an appearance of nano products has set not only a positive example of the scientific progress development and dynamics, but also a potential threat of possible risks for the environment and people's health in the case of its massive use when there is a lack of research about its impacts. In Russian Federation the problem of nanosafety regulation is extremely actual. A number of international documents have noted a lack of legal regulation in the sphere of nanotechnologies in Russian Federation. Thus, according to the strategic EU program, it's mentioned that in 2009 on an annual meeting of OECD Tour de Table Meeting in Paris (November, 2007) Russia took responsibility to develop a long term program of nanoindustry development by 2015 (Nanotechnology Action Plan for Russia-2015). The key role should be dedicated to the nanosafety aspects and potential risk assessment of nanomaterials for environment and humans' health. Unfortunately, until now Russia did not provide this document for discussion at the international level by the partners of nanoconsortcium. Indeed, from 2007 until nowadays in Russian Federation there are no a single federal act of legislation (federal'nyi zakon), establishing the state foundations of regulation of nanosafety. The only one Federeal Legal Act in the described sphere is the Federalniy Zakon from 19 July 2007 A bout the Russian corporation of nanotechnologies , which has established the principles of organization, activites, functions and termination of Rosnanotech. However, there are no articles dedicated to the environmental safety provision in regards of nano products applications. Also there is no complex federal act consolidating legal status of action in the field of

  8. Legal issues of the environmental safety regulation in the sphere of nanotechnology in Russian Federation

    Science.gov (United States)

    Belokrylova, Ekaterina A.

    2013-04-01

    Nowadays one of the principal innovative spheres in Russia is considered to be a rapid development of nanotechnology and nanomaterials and implementation its products into almost all fields of social and industrial life. Nevertheless, despite the pointed advantages an appearance of nano products has set not only a positive example of the scientific progress development and dynamics, but also a potential threat of possible risks for the environment and people's health in the case of its massive use when there is a lack of research about its impacts. In Russian Federation the problem of nanosafety regulation is extremely actual. A number of international documents have noted a lack of legal regulation in the sphere of nanotechnologies in Russian Federation. Thus, according to the strategic EU program, it's mentioned that in 2009 on an annual meeting of OECD Tour de Table Meeting in Paris (November, 2007) Russia took responsibility to develop a long term program of nanoindustry development by 2015 (Nanotechnology Action Plan for Russia-2015). The key role should be dedicated to the nanosafety aspects and potential risk assessment of nanomaterials for environment and humans' health. Unfortunately, until now Russia did not provide this document for discussion at the international level by the partners of nanoconsortcium. Indeed, from 2007 until nowadays in Russian Federation there are no a single federal act of legislation (federal'nyi zakon), establishing the state foundations of regulation of nanosafety. The only one Federeal Legal Act in the described sphere is the Federalniy Zakon from 19 July 2007 "About the Russian corporation of nanotechnologies", which has established the principles of organization, activites, functions and termination of Rosnanotech. However, there are no articles dedicated to the environmental safety provision in regards of nano products applications. Also there is no complex federal act consolidating legal status of action in the field of

  9. International trade agreements, environmental policy, and relocation of production

    International Nuclear Information System (INIS)

    Eerola, Essi

    2006-01-01

    This paper studies the influence of free trade agreements on national environmental policies and location strategies of polluting firms. It is shown that banning export subsidies makes relocation of production more attractive for firms. When export subsidies are banned relocation is profitable because: (1) the rival firm reduces output due to more stringent emission regulation in the host country of the investment and (2) relocation leads to lower emission tax rate in the original home country of the investing firm. When export subsidies are used, the first effect is absent because the host government is able to use the export subsidy to compensate the negative effect of more stringent emission taxation on domestic shareholders. (author)

  10. Impact of Environmental Regulation and Technical Progress on Industrial Carbon Productivity: An Approach Based on Proxy Measure

    Directory of Open Access Journals (Sweden)

    Huan Zhang

    2016-08-01

    Full Text Available This research aims to study the main influencing factors of China’s industrial carbon productivity by incorporating environmental regulation and technical progress into an econometric model. The paper focuses on data from 35 of China’s industrial sectors and covers the period from 2006 to 2014, in order to examine the impact of environmental regulation and technical progress on carbon productivity. Methods applied include panel fixed effect model, panel random effect model and two stage least squares with instrumental variables (IV-2SLS. The effect of environmental regulation and technical progress has industrial heterogeneity. The paper subdivides industrial sectors into capital and technology intensive, resource intensive and labor intensive sectors according to factor intensiveness. The estimation results of the subgroups have uncovered that for capital and technology intensive and resource intensive sectors, environmental regulation has a more significant impact than technical progress; while for labor intensive sectors, innovation more significantly influences carbon productivity. In addition, foreign direct investment (FDI and industrialization level facilitate improving carbon productivity for the full sample. By contrast, industrial structure inhibits the overall industrial carbon productivity. The industry-specific results indicate that for capital and technology intensive sectors, optimizing of the industrial structure can improve carbon productivity; for resource intensive sectors, FDI and energy consumption structure should be emphasized more; for labor intensive sectors, industrialization levels help enhance carbon productivity. Finally the industrial sector-specific policy suggestions are proposed.

  11. Environmental concerns and regulatory initiatives related to hydraulic fracturing in shale gas formations: potential implications for North American gas supply

    Energy Technology Data Exchange (ETDEWEB)

    Sumi, Lisa [Earthworks (Canada)

    2010-09-15

    Shale gas resources have been referred to as a game changer for North America and it is expected that shale gas will account for over 30% of the natural gas production in North America by 2020. However, the development of this resource has raised several concerns, notably in terms of water use and contamination; more stringent regulations could be implemented in the coming years. The aim of this paper is to present the effect that more stringent regulations would have on gas development in the Marcellus shale, which accounts for 20% of North American shale gas production. Information on hydraulic fracturing and its environmental impacts is provided herein, along with information on the regulatory initiatives underway in the Marcellus shale region. This paper pointed out that novel regulations relating to shale gas development could significantly reduce the growth in shale gas production.

  12. Recent developments in environmental regulations and their impact on the U.S. refining industry

    International Nuclear Information System (INIS)

    Tahmassebi, C.H.

    1991-01-01

    Public concern over the environment has heightened considerably since the hot, dry summer of 1988. Responding to these concerns, the administration and Congress have initiated a number of measures to address such issues as acid rain, ozone depletion, smog, and global climate change. Most of these measures are aimed at the oil industry or energy-producing companies. They cone on the heels of other costly environmental legislation, to phase out lead in gasoline and reduce gasoline volatility. Additional measures aimed at different segments of the oil industry (production, refining, and retailing) are expected. In analyzing the merits of these policies, one must address the following issues: the feasibility of reaching an optimum point for these regulatory measures, considering the potential costs and benefits; the ramifications of such measures on the U.S. oil industry, particularly on the U.S. refining industry; the costs to the final consumer and the economy; and the effects of the implementation of such regulations by other countries and our trading partners. The purpose of this paper is to discuss the concerns raised above, particularly as they relate to the U.S. refining industry

  13. Life cycle environmental evaluation of kettles: Recommendations for the development of eco-design regulations in the European Union.

    Science.gov (United States)

    Gallego-Schmid, Alejandro; Jeswani, Harish Kumar; Mendoza, Joan Manuel F; Azapagic, Adisa

    2018-06-01

    Between 117 and 200 million kettles are used in the European Union (EU) every year. However, the full environmental impacts of kettles remain largely unknown. This paper presents a comprehensive life cycle assessment of conventional plastic and metallic kettles in comparison with eco-kettles. The results show that the use stage contributes 80% to the impacts. For this reason, the eco-kettle has over 30% lower environmental impacts due to a greater water efficiency and related lower energy consumption. These results have been extrapolated to the EU level to consider the implications for proposed eco-design regulations. For these purposes, the effects on the impacts of durability of kettles and improvements in their energy and water efficiency have been assessed as they have been identified as two key parameters in the proposed regulations. The results suggest that increasing the current average durability from 4.4 to seven years would reduce the impacts by less than 5%. Thus, improving durability is not a key issue for improving the environmental performance of kettles and does not justify the need for an eco-design regulation based exclusively on it. However, improvements in water and energy efficiency through eco-design can bring relevant environmental savings. Boiling the exact amount of water needed would reduce the impacts by around a third and using water temperature control by further 2%-5%. The study has also considered the effects of reducing significantly the number of kettles in use after the UK (large user of kettles) leaves the EU and reducing the excess water typically boiled by the consumer. Even under these circumstances, the environmental savings justify the development of a specific EU eco-design regulation for kettles. However, consumer engagement will be key to the implementation and achievement of the expected environmental benefits. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Impacts of proposed RCRA regulations and other related federal environmental regulations on Fossil Fuel-Fired Facilities: Final report, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1987-03-01

    In order to fulfill its responsibilities, DOE contracted with Engineering-Science to perform a multi-phase engineering and economics study to evaluate the impact of the proposed RCRA regulations and other related federal environmental regulations on coal-fired utilities. This Interim Phase I report presents the findings of the impacts of proposed RCRA and related federal regulations on the utility sector fossil fuel-fired facilities. Subsequent phases involve parallel engineering studies on the industrial sector as well as economic evaluations. The framework of this study was based on the development and analysis (engineering and economic) of four regulatory scenarios for the disposal of fly ash, bottom ash and FGD sludge from the utility industry.

  15. Stringent factor and proteolysis control of sigma factor RpoS expression in Vibrio cholerae.

    Science.gov (United States)

    Wurm, Philipp; Tutz, Sarah; Mutsam, Beatrice; Vorkapic, Dina; Heyne, Barbara; Grabner, Claudia; Kleewein, Katharina; Halscheidt, Anja; Schild, Stefan; Reidl, Joachim

    2017-04-01

    Vibrio cholerae can colonize the gastrointestinal track of humans and cause the disease cholera. During colonization, the alternative sigma factor, RpoS, controls a process known as "mucosal escape response," defining a specific spatial and temporal response and effecting chemotaxis and motility. In this report, the expression and proteolytic control of RpoS in V. cholerae was characterized. To date, aspects of proteolysis control, the involved components, and proteolysis regulation have not been addressed for RpoS in V. cholerae. Similar to Escherichia coli, we find that the RpoS protein is subjected to regulated intracellular proteolysis, which is mediated by homologues of the proteolysis-targeting factor RssB and the protease complex ClpXP. As demonstrated, RpoS expression transiently peaks after cells are shifted from rich to minimal growth medium. This peak level is dependent on (p)ppGpp-activated rpoS transcription and controlled RpoS proteolysis. The RpoS peak level also correlates with induction of a chemotaxis gene, encoding a methyl-accepting chemotaxis protein, earlier identified to belong to the mucosal escape response pathway. These results suggest that the RpoS expression peak is linked to (p)ppGpp alarmone increase, leading to enhanced motility and chemotaxis, and possibly contributing to the mucosal escape response. Copyright © 2017 Elsevier GmbH. All rights reserved.

  16. An evaluation of a risk-based environmental regulation in Brazil: Limitations to risk management of hazardous installations

    International Nuclear Information System (INIS)

    Naime, Andre

    2017-01-01

    The environmental regulation of hazardous projects with risk-based decision-making processes can lead to a deficient management of human exposure to technological hazards. Such an approach for regulation is criticized for simplifying the complexity of decisions involving the economic, social, and environmental aspects of the installation and operation of hazardous facilities in urban areas. Results of a Brazilian case study indicate that oil and gas transmission pipelines may represent a threat to diverse communities if the relationship between such linear projects and human populations is overlooked by regulatory bodies. Results also corroborate known challenges to the implementation of EIA processes and outline limitations to an effective environmental and risk management. Two preliminary topics are discussed to strengthen similar regulatory practices. Firstly, an effective integration between social impact assessment and risk assessment in EIA processes to have a more comprehensive understanding of the social fabric. Secondly, the advancement of traditional management practices for hazardous installations to pursue a strong transition from assessment and evaluation to management and control and to promote an effective interaction between land-use planning and environmental regulation.

  17. An Investigation of Taiwan's Education Regulations and Policies for Pursuing Environmental Sustainability

    Science.gov (United States)

    Tsai, Wen-Tien

    2012-01-01

    With the rapid industrialization and economic development in the past decades, heavy environmental loads caused some serious environmental scenarios in Taiwan, an island country with a dense population and only limited natural resources. As a result, environmental education in Taiwan has been a leading tool to promote sustainable development since…

  18. Differential regulation of c-di-GMP metabolic enzymes by environmental signals modulates biofilm formation in Yersinia pestis

    Directory of Open Access Journals (Sweden)

    Gai-Xian eRen

    2016-06-01

    Full Text Available Cyclic diguanylate (c-di-GMP is essential for Yersinia pestis biofilm formation, which is important for flea-borne blockage-dependent plague transmission. Two diguanylate cyclases (DGCs, HmsT and HmsD and one phosphodiesterase (PDE, HmsP are responsible for the synthesis and degradation of c-di-GMP in Y. pestis. Here, we systematically analyzed the effect of various environmental signals on regulation of the biofilm phenotype, the c-di-GMP levels, and expression of HmsT, HmsD and HmsP in Y. pestis. Biofilm formation was higher in the presence of nonlethal high concentration of CaCl2, MgCl2, CuSO4, sucrose, sodium dodecyl sulfonate, or dithiothreitol, and was lower in the presence of FeCl2 or NaCl. In addition, we found that HmsD plays a major role in biofilm formation in acidic or redox environments. These environmental signals differentially regulated expression of HmsT, HmsP and HmsD, resulting in changes in the intracellular levels of c-di-GMP in Y. pestis. Our results suggest that bacteria can sense various environmental signals, and differentially regulates their DGCs and PDEs to coordinately regulate and adapt metabolism of c-di-GMP and biofilm formation to changing environments.

  19. Environmental and Genetic Factors Regulating Localization of the Plant Plasma Membrane H+-ATPase.

    Science.gov (United States)

    Haruta, Miyoshi; Tan, Li Xuan; Bushey, Daniel B; Swanson, Sarah J; Sussman, Michael R

    2018-01-01

    A P-type H + -ATPase is the primary transporter that converts ATP to electrochemical energy at the plasma membrane of higher plants. Its product, the proton-motive force, is composed of an electrical potential and a pH gradient. Many studies have demonstrated that this proton-motive force not only drives the secondary transporters required for nutrient uptake, but also plays a direct role in regulating cell expansion. Here, we have generated a transgenic Arabidopsis ( Arabidopsis thaliana ) plant expressing H + -ATPase isoform 2 (AHA2) that is translationally fused with a fluorescent protein and examined its cellular localization by live-cell microscopy. Using a 3D imaging approach with seedlings grown for various times under a variety of light intensities, we demonstrate that AHA2 localization at the plasma membrane of root cells requires light. In dim light conditions, AHA2 is found in intracellular compartments, in addition to the plasma membrane. This localization profile was age-dependent and specific to cell types found in the transition zone located between the meristem and elongation zones. The accumulation of AHA2 in intracellular compartments is consistent with reduced H + secretion near the transition zone and the suppression of root growth. By examining AHA2 localization in a knockout mutant of a receptor protein kinase, FERONIA, we found that the intracellular accumulation of AHA2 in the transition zone is dependent on a functional FERONIA-dependent inhibitory response in root elongation. Overall, this study provides a molecular underpinning for understanding the genetic, environmental, and developmental factors influencing root growth via localization of the plasma membrane H + -ATPase. © 2018 American Society of Plant Biologists. All Rights Reserved.

  20. Toward the definition of specific protection goals for the environmental risk assessment of chemicals: A perspective on environmental regulation in Europe.

    Science.gov (United States)

    Brown, A Ross; Whale, Graham; Jackson, Mathew; Marshall, Stuart; Hamer, Mick; Solga, Andreas; Kabouw, Patrick; Galay-Burgos, Malyka; Woods, Richard; Nadzialek, Stephanie; Maltby, Lorraine

    2017-01-01

    This critical review examines the definition and implementation of environmental protection goals for chemicals in current European Union (EU) legislation, guidelines, and international agreements to which EU countries are party. The European chemical industry is highly regulated, and prospective environmental risk assessments (ERAs) are tailored for different classes of chemical, according to their specific hazards, uses, and environmental exposure profiles. However, environmental protection goals are often highly generic, requiring the prevention of "unacceptable" or "adverse" impacts on "biodiversity" and "ecosystems" or the "environment as a whole." This review aims to highlight working examples, challenges, solutions, and best practices for defining specific protection goals (SPGs), which are seen to be essential for refining and improving ERA. Specific protection goals hinge on discerning acceptable versus unacceptable adverse effects on the key attributes of relevant, sensitive ecological entities (ranging from organisms to ecosystems). Some isolated examples of SPGs for terrestrial and aquatic biota can be found in prospective ERA guidance for plant protection products (PPPs). However, SPGs are generally limited to environmental or nature legislation that requires environmental monitoring and retrospective ERA. This limitation is due mainly to the availability of baselines, which define acceptable versus unacceptable environmental effects on the key attributes of sentinel species, populations and/or communities, such as reproductive status, abundance, or diversity. Nevertheless, very few regulatory case examples exist in which SPGs incorporate effect magnitude, spatial extent, and temporal duration. We conclude that more holistic approaches are needed for defining SPGs, particularly with respect to protecting population sustainability, ecosystem function, and integrity, which are implicit in generic protection goals and explicit in the International

  1. Constraints upon the response of fish and crayfish to environmental flow releases in a regulated headwater stream network.

    Directory of Open Access Journals (Sweden)

    Edwin T Chester

    Full Text Available In dry climate zones, headwater streams are often regulated for water extraction causing intermittency in perennial streams and prolonged drying in intermittent streams. Regulation thereby reduces aquatic habitat downstream of weirs that also form barriers to migration by stream fauna. Environmental flow releases may restore streamflow in rivers, but are rarely applied to headwaters. We sampled fish and crayfish in four regulated headwater streams before and after the release of summer-autumn environmental flows, and in four nearby unregulated streams, to determine whether their abundances increased in response to flow releases. Historical data of fish and crayfish occurrence spanning a 30 year period was compared with contemporary data (electrofishing surveys, Victoria Range, Australia; summer 2008 to summer 2010 to assess the longer-term effects of regulation and drought. Although fish were recorded in regulated streams before 1996, they were not recorded in the present study upstream or downstream of weirs despite recent flow releases. Crayfish (Geocharax sp. nov. 1 remained in the regulated streams throughout the study, but did not become more abundant in response to flow releases. In contrast, native fish (Gadopsis marmoratus, Galaxias oliros, Galaxias maculatus and crayfish remained present in unregulated streams, despite prolonged drought conditions during 2006-2010, and the assemblages of each of these streams remained essentially unchanged over the 30 year period. Flow release volumes may have been too small or have operated for an insufficient time to allow fish to recolonise regulated streams. Barriers to dispersal may also be preventing recolonisation. Indefinite continuation of annual flow releases, that prevent the unnatural cessation of flow caused by weirs, may eventually facilitate upstream movement of fish and crayfish in regulated channels; but other human-made dispersal barriers downstream need to be identified and

  2. Management practices in Australasian ethical investment products: a role for environmental regulation?

    OpenAIRE

    Haigh, Matthew; Guthrie, James

    2010-01-01

    This paper adds to the literatures on socially responsible investment (SRI), investment management, regulation of financial services and social accounting by providing a comprehensive survey of investment methods used in SRI products and regulated social reporting in financial services. Australian and New Zealand regulations require issuers of self-declarative SRI products to provide details on methods used in portfolio construction. Regulators' objectives to standardize the reporting of port...

  3. Integrating environmental management into food safety and food packaging in Malaysia: review of the food regulation 1985

    Science.gov (United States)

    Nordin, N. H.; Hara, H.; Kaida, N.

    2017-05-01

    Food safety is an important issue that is related to public safety to prevent the toxicity threats of the food. Management through legal approach has been used in Malaysia as one of the predominant approaches to manage the environment. In this regard, the Food Regulation 1985 has been one of the mechanisms of environmental management through legal approach in controlling the safety of packaged food in food packaging industry in Malaysia. The present study aims to analyse and to explain the implementation of the Food Regulation 1985 in controlling the safety of packaged food in Malaysia and to integrate the concept of environmental management into the food safety issue. Qualitative analysis on the regulation document revealed that there are two main themes, general and specific, while their seven sub themes are included harmful packages, safety packages, reuse packages, polyvinyl chloride (PVC), alcoholic bottle, toys, money and others and iron powder. The implementation of the Food Regulation 1985 in controlling the safety of packaged food should not be regarded solely for regulation purposes but should be further developed for a broader sense of food safety from overcoming the food poisoning.

  4. A rapid response air quality analysis system for use in projects having stringent quality assurance requirements

    International Nuclear Information System (INIS)

    Bowman, A.W.

    1990-01-01

    This paper describes an approach to solve air quality problems which frequently occur during iterations of the baseline change process. From a schedule standpoint, it is desirable to perform this evaluation in as short a time as possible while budgetary pressures limit the size of the staff available to do the work. Without a method in place to deal with baseline change proposal requests the environment analysts may not be able to produce the analysis results in the time frame expected. Using a concept called the Rapid Response Air Quality Analysis System (RAAS), the problems of timing and cost become tractable. The system could be adapted to assess other atmospheric pathway impacts, e.g., acoustics or visibility. The air quality analysis system used to perform the EA analysis (EA) for the Salt Repository Project (part of the Civilian Radioactive Waste Management Program), and later to evaluate the consequences of proposed baseline changes, consists of three components: Emission source data files; Emission rates contained in spreadsheets; Impact assessment model codes. The spreadsheets contain user-written codes (macros) that calculate emission rates from (1) emission source data (e.g., numbers and locations of sources, detailed operating schedules, and source specifications including horsepower, load factor, and duty cycle); (2) emission factors such as those published by the U.S. Environmental Protection Agency, and (3) control efficiencies

  5. Financial and environmental behavior of the regulated firm: A case study of the US nuclear power industry, 1974-1984

    International Nuclear Information System (INIS)

    Mitchell, E.P.

    1991-01-01

    This study of the US commercial nuclear power industry from 1974-1984 covers the operations of 87 power plants. It seeks to help explain the actions of a regulated firm faced with environmental constraints from the Nuclear Regulatory Commission and financial constraints from State regulatory bodies. Theoretical and applied conceptions of the regulated monopoly are reviewed in a historical and integrated format using both the neoclassical and institutional positions. For the neoclassical approach, the author seeks empirical support for the Averch-Johnson hypothesis by including profit-maximizing and environmental constraints in his econometric model. For the institutionalist approach, he tries to look into the institutional reasons for the behavior exhibited by the firms. A date base which consists of financial, radioactive emissions, and technical operations information has been compiled in order to allow testing of various hypotheses drawn from theoretical and applied sources. The results of the analysis support five very clear conclusions which are presented

  6. A stringently controlled expression system for analysing lateral gene transfer between bacteria.

    Science.gov (United States)

    Jaenecke, S; de Lorenzo, V; Timmis, K N; Díaz, E

    1996-07-01

    The lateral transfer of genetic information among microorganisms is a major force driving the outstanding adaptability of microbial communities to environmental changes. Until now little information has been obtained on gene transfer in natural ecosystems. We present here a genetic circuit for detecting and quantifying horizontal gene transfer from a defined donor microorganism to recipient organisms in the absence of selection for a recipient-specific phenotype. The system consists of an engineered lacZ (encoding beta-galactosidase) reporter gene whose expression is controlled by a synthetic regulatory element based on a fusion between the Pr promoter-operator from lambda bacteriophage and the 5' non-coding leader region of the inp gene encoding the IS 10 transposase function. Expression of this reporter cassette in the recombinant microorganism is completely shut down by two chromosomally encoded trans-acting repressors working at the level of transcription (the Cl-EK117 protein from the lambda phage), and at the level of translation (the antisense RNA-OUT of the IS 10 element). When the reporter element is transferred to a different host by any mechanism, it escapes repression and becomes expressed. The system was validated with Pseudo-monas putida, and conjugational transfer frequencies of the reporter element as low as 10(-6) were detected. The modular design and broad host range of the genetic circuit, in combination with biomarkers which permit real-time in situ detection, will facilitate the monitor-ing of gene flow in a non-disruptive manner within the environment.

  7. Moderate forest disturbance as a stringent test for gap and big-leaf models

    Science.gov (United States)

    Bond-Lamberty, B.; Fisk, J. P.; Holm, J. A.; Bailey, V.; Bohrer, G.; Gough, C. M.

    2015-01-01

    Disturbance-induced tree mortality is a key factor regulating the carbon balance of a forest, but tree mortality and its subsequent effects are poorly represented processes in terrestrial ecosystem models. It is thus unclear whether models can robustly simulate moderate (non-catastrophic) disturbances, which tend to increase biological and structural complexity and are increasingly common in aging US forests. We tested whether three forest ecosystem models - Biome-BGC (BioGeochemical Cycles), a classic big-leaf model, and the ZELIG and ED (Ecosystem Demography) gap-oriented models - could reproduce the resilience to moderate disturbance observed in an experimentally manipulated forest (the Forest Accelerated Succession Experiment in northern Michigan, USA, in which 38% of canopy dominants were stem girdled and compared to control plots). Each model was parameterized, spun up, and disturbed following similar protocols and run for 5 years post-disturbance. The models replicated observed declines in aboveground biomass well. Biome-BGC captured the timing and rebound of observed leaf area index (LAI), while ZELIG and ED correctly estimated the magnitude of LAI decline. None of the models fully captured the observed post-disturbance C fluxes, in particular gross primary production or net primary production (NPP). Biome-BGC NPP was correctly resilient but for the wrong reasons, and could not match the absolute observational values. ZELIG and ED, in contrast, exhibited large, unobserved drops in NPP and net ecosystem production. The biological mechanisms proposed to explain the observed rapid resilience of the C cycle are typically not incorporated by these or other models. It is thus an open question whether most ecosystem models will simulate correctly the gradual and less extensive tree mortality characteristic of moderate disturbances.

  8. Public Participation Planning of Environmental Impact Assessment (EIA and Regulations: Analysis of Inconsistency for Some Cases in Indonesia

    Directory of Open Access Journals (Sweden)

    Hindrayani Aniek

    2018-01-01

    Full Text Available The failure in community involvement during the environmental documents planning may result in the failure of the planned project implementation. This study aims to determine the gap between practices and regulations that apply to the process of community involvement in the environmental documents planning, and find out inconsistency of implementation on each stakeholder in the planning of the Environmental Impact Assessment (EIA and the environmental permit. The method used was qualitative through interview and literature study which is analyzed using triangulation model and presented in the form of concept map. The results of the study indicate that 1 the determination of community representatives based on the criteria of the impacted communities is not clearly described, 3 suggestions, opinions, and responses to the environmental impact management are not well implemented by the project proponent, 3 implementation of the environmental management of other licensed activities affecting the behavior (4 stakeholders (project proponent, EIA consultants, and EIA appraisal committee do not play their role as mandated in applicable legislation.

  9. Public Participation Planning of Environmental Impact Assessment (EIA) and Regulations: Analysis of Inconsistency for Some Cases in Indonesia

    Science.gov (United States)

    Hindrayani, Aniek; Purwanto

    2018-02-01

    The failure in community involvement during the environmental documents planning may result in the failure of the planned project implementation. This study aims to determine the gap between practices and regulations that apply to the process of community involvement in the environmental documents planning, and find out inconsistency of implementation on each stakeholder in the planning of the Environmental Impact Assessment (EIA) and the environmental permit. The method used was qualitative through interview and literature study which is analyzed using triangulation model and presented in the form of concept map. The results of the study indicate that 1) the determination of community representatives based on the criteria of the impacted communities is not clearly described, 3) suggestions, opinions, and responses to the environmental impact management are not well implemented by the project proponent, 3) implementation of the environmental management of other licensed activities affecting the behavior (4) stakeholders (project proponent, EIA consultants, and EIA appraisal committee) do not play their role as mandated in applicable legislation.

  10. Multi-layered environmental regulation on the homeostasis of stem cells: The saga of hair growth and alopecia

    Science.gov (United States)

    Chen, Chih-Chiang; Chuong, Cheng Ming

    2013-01-01

    Stem cells are fascinating because of their potential in regenerative medicine. Stem cell homeostasis has been thought to be mainly regulated by signals from their adjacent micro-environment named the “stem cell niche”. However, recent studies reveal that there can be multiple layers of environmental controls. Here we review these environmental controls using the paradigm of hair stem cells, because to observe and analyze the growth of hair is easier due to their characteristic cyclic regeneration pattern. The length of hair fibers is regulated by the duration of the growth period. In the hair follicles, hair stem cells located in the follicle bulge interact with signals from the dermal papilla. Outside of the follicle, activation of hair stem cells has been shown to be modulated by molecules released from the intra-dermal adipose tissue as well as body hormone status, immune function, neural activities, and aging. The general physiological status of an individual is further influenced by circadian rhythms and changing seasons. The interactive networks of these environmental factors provide new understanding on how stem cell homeostasis is regulated, inspiring new insights for regenerative medicine. Therapies do not necessarily have to be achieved by using stem cells themselves which may constitute a higher risk but by modulating stem cell activity through targeting one or multiple layers of their micro- and macro-environments. PMID:22391240

  11. The role of cis-zeatin-type cytokinins in plant growth regulation and mediating responses to environmental interactions

    DEFF Research Database (Denmark)

    Schäfer, Martin; Brütting, Christoph; Meza-Canales, Ivan David

    2015-01-01

    -zeatin and isopentenyladenine-type CKs, have been studied in detail, the role of cis-zeatin-type CKs (cZs) in plant development and in mediating environmental interactions is less well defined. Here we provide a comprehensive summary of the current knowledge about abundance, metabolism and activities of cZs in plants. We...... outline the history of their analysis and the metabolic routes comprising cZ biosynthesis and degradation. Further we provide an overview of changes in the pools of cZs during plant development and environmental interactions. We summarize studies that investigate the role of cZs in regulating plant...... experimental approaches using transgenic plants altered in cZ levels to further uncover their roles in plant growth and environmental interactions and their potential for crop improvement....

  12. Regulatory analysis for amendments to regulations for the environmental review for renewal of nuclear power plant operating licenses. Final report

    International Nuclear Information System (INIS)

    1996-05-01

    This regulatory analysis provides the supporting information for a proposed rule that will amend the Nuclear Regulatory Commission's environmental review requirements for applications for renewal of nuclear power plant operating licenses. The objective of the proposed rulemaking is to improve regulatory efficiency by providing for the generic evaluation of certain environmental impacts associated with nuclear plant license renewal. After considering various options, the staff identified and analyzed two major alternatives. With Alternative A, the existing regulations would not be amended. This option requires that environmental reviews be performed under the existing regulations. Alternative B is to assess, on a generic basis, the environmental impacts of renewing the operating license of individual nuclear power plants, and define the issues that will need to be further analyzed on a case-by-case basis. In addition, Alternative B removes from NRC's review certain economics-related issues. The findings of this assessment are to be codified in 10 CFR 51. The staff has selected Alternative B as the preferred alternative

  13. 76 FR 40368 - Federal Acquisition Regulation; Submission for OMB Review; Environmentally Sound Products

    Science.gov (United States)

    2011-07-08

    ...; Submission for OMB Review; Environmentally Sound Products AGENCIES: Department of Defense (DOD), General... submitting to the Office of Management and Budget (OMB) a request to review and approve an extension of a previously approved information collection requirement concerning environmentally sound products. DATES...

  14. 28 CFR 91.68 - Compliance with other Federal environmental statutes, regulations and executive orders.

    Science.gov (United States)

    2010-07-01

    ..., (6) Federal Water Pollution Control Act, (7) Endangered Species Act, (8) Wild and Scenic Rivers Act... OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review Procedures for... applicable, to the environmental impact analysis requirements of the following statutes, their implementing...

  15. The Effect of Environmental Regulation on Employment in Resource-Based Areas of China—An Empirical Research Based on the Mediating Effect Model

    Science.gov (United States)

    Cao, Wenbin; Wang, Hui; Ying, Huihui

    2017-01-01

    While environmental pollution is becoming more and more serious, many countries are adopting policies to control pollution. At the same time, the environmental regulation will inevitably affect economic and social development, especially employment growth. The environmental regulation will not only affect the scale of employment directly, but it will also have indirect effects by stimulating upgrades in the industrial structure and in technological innovation. This paper examines the impact of environmental regulation on employment, using a mediating model based on the data from five typical resource-based provinces in China from 2000 to 2015. The estimation is performed based on the system GMM (Generalized Method of Moments) estimator. The results show that the implementation of environmental regulation in resource-based areas has both a direct effect and a mediating effect on employment. These findings provide policy implications for these resource-based areas to promote the coordinating development between the environment and employment. PMID:29257068

  16. The Effect of Environmental Regulation on Employment in Resource-Based Areas of China-An Empirical Research Based on the Mediating Effect Model.

    Science.gov (United States)

    Cao, Wenbin; Wang, Hui; Ying, Huihui

    2017-12-19

    While environmental pollution is becoming more and more serious, many countries are adopting policies to control pollution. At the same time, the environmental regulation will inevitably affect economic and social development, especially employment growth. The environmental regulation will not only affect the scale of employment directly, but it will also have indirect effects by stimulating upgrades in the industrial structure and in technological innovation. This paper examines the impact of environmental regulation on employment, using a mediating model based on the data from five typical resource-based provinces in China from 2000 to 2015. The estimation is performed based on the system GMM (Generalized Method of Moments) estimator. The results show that the implementation of environmental regulation in resource-based areas has both a direct effect and a mediating effect on employment. These findings provide policy implications for these resource-based areas to promote the coordinating development between the environment and employment.

  17. The effects of customer benefit and regulation on environmental product innovation. Empirical evidence from appliance manufacturers in Germany

    International Nuclear Information System (INIS)

    Kammerer, Daniel

    2009-01-01

    Environmental product (EP) innovations and their determinants have received increasing attention from researchers during the past years. So far, empirical studies have shown inconsistent results, especially regarding the impact of regulation. In this paper, I seek to advance the understanding of EP-innovation by introducing and testing a novel research framework. First, a novel unit of analysis, the environmental issue level, is applied. EP-innovation is not studied in broad terms but specifically for four environmental issues that are relevant to the electrical and electronic appliances industry: energy efficiency, toxic substances, material efficiency, and electromagnetic fields. Second, the customer benefit, a concept from the green marketing literature, is included as an explanatory variable for EP-innovation for the first time. The argument is that green products which besides their public benefits have private environmental benefits for the customer (e.g., energy savings) will generate stronger consumer demand and can thus constitute the firm's motivation to implement those innovations in the first place. Third, EP-innovation is observed more comprehensively, measuring its extent and level of novelty. I apply this research framework to study EP-innovations of German manufacturers of electrical and electronic appliances. My results support the issue level as unit of analysis. The impact of customer benefit and regulation on EP-innovation is analyzed with logit regression and the results clearly show that both customer benefit and regulation play a key role for EP-innovation. They not only foster the implementation of EP-innovations but also their broad application and their level of novelty. (author)

  18. New insights into the regulatory pathways associated with the activation of the stringent response in bacterial resistance to the PBP2-targeted antibiotics, mecillinam and OP0595/RG6080.

    Science.gov (United States)

    Doumith, M; Mushtaq, S; Livermore, D M; Woodford, N

    2016-10-01

    The diazabicyclooctane β-lactamase inhibitor OP0595 (RG6080) also acts as an antibiotic, targeting PBP2 in Enterobacteriaceae, but this activity is vulnerable to mutational resistance. We used WGS to investigate the basis of this resistance. Twenty OP0595-selected mutants, comprising four derived from each of five different Escherichia coli strains, were sequenced on Illumina HiSeq. Reads from each mutant were mapped to the assembled genome of the corresponding parent. A variant-calling file generated with Samtools was parsed to determine genetic alterations. Besides OP0595, the mutants consistently showed decreased susceptibility to mecillinam, which likewise targets PBP2, and grew as stable round forms in the presence of subinhibitory concentrations of OP0595. Among the 20 mutants, 18 had alterations in genes encoding tRNA synthase and modification functions liable to induce expression of the RpoS sigma factor through activation of the stringent response or had mutations suppressing inactivators of RpoS or the stringent response signal-degrading enzyme, SpoT. TolB was inactivated in one mutant: this activates RcsBC regulation and was previously associated with mecillinam resistance. The mechanism of resistance remained unidentified in one mutant. Both the RpoS and RcsBC systems regulate genes of cell division, including ftsAQZ that can compensate for loss or inhibition of PBP2, allowing survival of the challenged bacteria as stable round forms, as seen. WGS identified the global stringent response signal, entailing induction of RpoS, as the main mediator of mutational resistance to OP0595 in E. coli. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  19. The Role of Environmental Civil Liability in Regulation of Marine Oil Pollution in Norway

    OpenAIRE

    Denissova, Ekaterina

    2008-01-01

    Awareness of domestic and international environmental issues has long been high in Norway. As far as marine oil pollution is concerned, Norway is exposed to coastal water pollution arising from such strategically important sectors as the petroleum industry and oil transportation. This paper is an attempt to make a positive economic analysis of environmental civil liability for marine oil pollution in these two sectors. In the theoretical part of this paper (section 2) the standard model o...

  20. Off-road compression-ignition engine emission regulations under the Canadian Environmental Protection Act 1999 : guidance document

    International Nuclear Information System (INIS)

    2006-03-01

    This guide explained the requirements for Off-Road Compression Ignition Engine Emission Regulations established under the Canadian Environmental Protection Act. The regulations are enforced by Environment Canada, which authorizes and monitors the use of the national emissions mark. The regulations prescribe standards for off-road engines that operate as reciprocating, internal combustion engines, other than those that operate under characteristics similar to the Otto combustion cycle and that use a spark plug or other sparking device. The regulations apply to engines that are typically diesel-fuelled and found in construction, mining, farming and forestry machines such as tractors, excavators and log skidders. Four different types of persons are potentially affected by the regulations: Canadian engine manufacturers; distributors of Canadian engines or machines containing Canadian engines; importers of engines or machines for the purpose of sale; and persons not in companies importing engines or machines. Details of emission standards were presented, as well as issues concerning evidence of conformity, importing engines, and special engine cases. Compliance and enforcement details were reviewed, as well as applicable standards and provisions for emission control systems and defeat devices; exhaust emissions; crankcase and smoke emissions; and adjustable parameters. Details of import declarations were reviewed, as well as issues concerning defects and maintenance instructions. 4 tabs., 4 figs

  1. Integrated cropping systems : an answer to environmental regulations imposed on nursery stock in the Netherlands

    NARCIS (Netherlands)

    Pronk, A.A.; Challa, H.

    2000-01-01

    Government regulations in the Netherlands are increasingly constraining and sometimes even banning conventional cultivation practices in nursery stock cropping systems. As a consequence, growers face problems concerning the use of manure, fertilisers and irrigation. In this study we analysed the

  2. The implementation of modern digital technology in x-ray medical diagnosis in Republic of Moldova - a stringent necessity

    International Nuclear Information System (INIS)

    Rosca, Andrei

    2011-01-01

    The study includes analyses of current technical state of radiodiagnostic equipment from the Public Medico-Sanitary Institution of Ministry of Health of Republic of Moldova (IMSP MS RM). The traditional radiodiagnostic apparatuses were morally and physically outrun at 96,6% (in regional MSPI - 93,5%), inclusive the dental one - 92,0% (in raional MSPI - 97,2%), X-Ray exam -100%, mobile - 84,1% etc. The exploitation of the traditional radiodiagnostic apparatuses with high degree of physical and moral wear essentially diminished the quality of profile investigation, creates premises for diagnostic error perpetrating, increase the collective ionizing irradiation of population etc. In recent years the subvention of MSPI HM RM with digital radiodiagnostic equipment was started. This process is very hard unfold because of grave socio-economic crises in Republic of Moldova. Despite these obstacles the subvention of MSPI HM RM with digital equipment represents a stringent necessity and a time request.

  3. The mechanism of heterogeneous beta-lactam resistance in MRSA: key role of the stringent stress response.

    Directory of Open Access Journals (Sweden)

    Choonkeun Kim

    Full Text Available All methicillin resistant S. aureus (MRSA strains carry an acquired genetic determinant--mecA or mecC--which encode for a low affinity penicillin binding protein -PBP2A or PBP2A'--that can continue the catalysis of peptidoglycan transpeptidation in the presence of high concentrations of beta-lactam antibiotics which would inhibit the native PBPs normally involved with the synthesis of staphylococcal cell wall peptidoglycan. In contrast to this common genetic and biochemical mechanism carried by all MRSA strains, the level of beta-lactam antibiotic resistance shows a very wide strain to strain variation, the mechanism of which has remained poorly understood. The overwhelming majority of MRSA strains produce a unique--heterogeneous--phenotype in which the great majority of the bacteria exhibit very poor resistance often close to the MIC value of susceptible S. aureus strains. However, cultures of such heterogeneously resistant MRSA strains also contain subpopulations of bacteria with extremely high beta-lactam MIC values and the resistance level and frequency of the highly resistant cells in such strain is a characteristic of the particular MRSA clone. In the study described in this communication, we used a variety of experimental models to understand the mechanism of heterogeneous beta-lactam resistance. Methicillin-susceptible S. aureus (MSSA that received the mecA determinant in the laboratory either on a plasmid or in the form of a chromosomal SCCmec cassette, generated heterogeneously resistant cultures and the highly resistant subpopulations that emerged in these models had increased levels of PBP2A and were composed of bacteria in which the stringent stress response was induced. Each of the major heterogeneously resistant clones of MRSA clinical isolates could be converted to express high level and homogeneous resistance if the growth medium contained an inducer of the stringent stress response.

  4. Global energy scenarios meeting stringent CO2 constraints - cost-effective fuel choices in the transportation sector

    International Nuclear Information System (INIS)

    Azar, Christian; Lindgren, Kristian; Andersson, B.A.

    2003-01-01

    The purpose of this paper is to assess fuel choices in the transportation sector under stringent global carbon constraints. Three key questions are asked: (i) when is it cost-effective to carry out the transition away from gasoline/diesel; (ii) to which fuel is it cost-effective to shift; and (iii) in which sector is biomass most cost-effectively used? These questions are analyzed using a global energy systems model (GET 1.0), with a transportation module, where vehicle costs (fuel cell, reformer and storage tank), infrastructure and primary energy availability are treated explicitly. The model is run under the assumption that atmospheric concentrations of CO 2 should be stabilized at 400 ppm. Three main results emerge: (i) despite the stringent CO 2 constraints, oil-based fuels remain dominant in the transportation sector over the next 50 years; and (ii) once a transition towards alternative fuels takes place, the preferred choice of fuel is hydrogen, even if we assume that hydrogen fuel cell vehicles are substantially more costly than methanol fuel cell vehicles. There may, under some circumstances, be a transient period of several decades with a significant share of methanol in the transportation sector. (iii) Biomass is most cost-effectively used in the heat and process heat sectors. If carbon sequestration from biomass is allowed, biomass is primarily used for hydrogen generation since small-scale heat applications are not suitable for carbon sequestration. Detailed sensitivity analyses show that these results are robust with respect to several parameters. Some policy conclusions are drawn

  5. Does environmental regulation affect energy efficiency in China's thermal power generation? Empirical evidence from a slacks-based DEA model

    International Nuclear Information System (INIS)

    Bi, Gong-Bing; Song, Wen; Zhou, P.; Liang, Liang

    2014-01-01

    Data envelopment analysis (DEA) has gained much popularity in performance measurement of power industry. This paper presents a slack-based measure approach to investigating the relationship between fossil fuel consumption and the environmental regulation of China's thermal power generation. We first calculate the total-factor energy efficiency without considering environmental constraints. An environmental performance indicator is proposed through decomposing the total-factor energy efficiency. The proposed approach is then employed to examine whether environmental regulation affects the energy efficiency of China's thermal power generation. We find that the environmental efficiency plays a significant role in affecting energy performance of China's thermal generation sector. Decreasing the discharge of major pollutants can improve both energy performance and environmental efficiency. Besides, we also have three main findings: (1) The energy efficiency and environmental efficiency were relatively low. (2) The energy and environmental efficiency scores show great variations among provinces. (3) Both energy efficiency and environmental efficiency are of obvious geographical characteristics. According to our findings, we suggest some policy implications. - Highlights: • We assess the energy efficiency and the environmental efficiency of China's thermal power generation simultaneously. • The energy efficiency and the environmental efficiency were relatively low during 2007–2009. • The energy efficiency and environmental efficiency show obvious geographic characters. • The environmental performance of a DMU plays a decisive role in the energy performance

  6. Nuclear controls are stringent

    International Nuclear Information System (INIS)

    Sonnekus, D.

    1983-01-01

    The peace-time application of nuclear power in South Africa, the organisations concerned and certain provisions laid down by the Act on Nuclear Energy, aimed at safeguarding the general public, are discussed

  7. Environmental impact evaluation: law no. 16.466 of 1994 01 14 and regulations

    International Nuclear Information System (INIS)

    2007-01-01

    No.16.466 law of January 9, 1994, known as the Law on Prevention and Environmental Impact Assessment EIA or just law is probably the law marked the beginning of a new generation of environmental standards in Uruguay, together with other like Hazardous Waste Act (Act 17 220 1999), the law of Natural Protected Areas System (Law 17 234 2000) and especially the General Law Protection Environment (Law no. 17 283 of November 28, 2000), but which also reaches to the Constitution of the Republic, with the inclusion of environment in the new wording of Article 47 of the 1996 reform.

  8. Legal regulations of subsoil use and environmental protection in the Khanti-Mansiisk Autonomous Okrug of the Russian Federation

    Energy Technology Data Exchange (ETDEWEB)

    Chebotarev, G.; Gladun, E. F. [Tyumen State University, (Russian Federation)

    2001-06-30

    Factors involved in the development of legislation to define the legal basis for subsoil-use regulation and environmental protection in the Khanti-Mansiisk Autonomous Okrug, a constituent part of the Russian Federation, is described. A parallel is drawn between these efforts and the protection afforded in Canada, and especially in the Province of Alberta, to subsoil use, with particular praise reserved for the involvement of indigenous people in formulating the Canadian legislation. The process in Canada was aided by the much clearer definition of the powers of the different levels of governments. In the opinion of the authors a more precise delimitation of the of the authority of government agencies of the Russian Federation, its subjects and local government agencies is essential before effective environmental protection legislation can be developed. The Canadian experience is cited as a good example of how these changes could be implemented in Russia. 11 end notes.

  9. CARABID BEATLES AS INDICATORS REFLECTING RIVERINE ENVIRONMENTAL CONDITIONS IN DIFFERENT TYPES OF RIVER REGULATIONS

    Directory of Open Access Journals (Sweden)

    Renata Kędzior

    2014-10-01

    Full Text Available The aim of the investigation was to estimate factors responsible for sustaining riverine communities in stream sections with various bank regulation systems. The research were conducted on Porebianka stream in the Polish Western Carpathians, where 10 different types of river regulations were chosen for the analysis (strong incision without alluvial deposits, redeposition with sand and gravel banks, concrete revetment walls along the banks, channel with banks lined with rip-rap and reference unmanaged cross- section. We conclude that the carabid beetles assemblages of the studied river sections respond mainly to hydraulic parameters of the stream. Elimination of frequent natural bank inundation (due to the regulations of the banks is the main factor responsible for the impoverishment and extinction of riverine communities.

  10. Environmental impact assessment modern dressed? To the amendment of the EIA act and other acts and regulations

    International Nuclear Information System (INIS)

    Feldmann, Ulrike

    2017-01-01

    On 22 December 2016, the Federal Ministry for the Environment (BMUB) presented the ''Draft Act for the Modernization of the Act on the Environmental Impact Assessment'' within the framework of the association consultation, as well as the ''Draft first Ordinance Amending the Ordinance on the Approval Procedure - 9. BImSchV''. The EIA Modernization Act as well as the Atomic Act Procedure Regulation and the Federal Mining Act should be revised by terms of an omnibus act. The association consultation was held on 18 January 2017.

  11. Energy and environmental quality of buildings and open space. Public administration regulations

    International Nuclear Information System (INIS)

    1998-01-01

    Residential sector is responsible of a third of total energy consumption in Italy and 30-40% of CO 2 emission. An energy efficient buildings reduce cost and save energy and emission. The energy recovery is possible also with bioclimatic architecture that represents a contribution at the economic and environmental balance [it

  12. 75 FR 8935 - Environmental Impact Statements and Regulations; Availability of EPA Comments

    Science.gov (United States)

    2010-02-26

    ... (ERP), under section 309 of the Clean Air Act and Section 102(2)(c) of the National Environmental... of availability of EPA comments in the Federal Register. Draft EISs EIS No. 20090272, ERP No. D-UAF.... Rating EC2. EIS No. 20090363, ERP No. D-SFW-G99004-TX, Hays County Regional Habitat Conservation Plan...

  13. 75 FR 6025 - Environmental Impact Statements and Regulations; Availability of EPA Comments

    Science.gov (United States)

    2010-02-05

    ... (ERP), under section 309 of the Clean Air Act and Section 102(2)(c) of the National Environmental.... 20090210, ERP No. D-FRC-A03087-00, Ruby Pipeline Project, Proposed Natural Gas Pipeline Facilities, Right... hydrostatic pipeline testing. Rating EC2. EIS No. 20090267, ERP No. D-AFS-J65546-MT, Bitterroot National...

  14. Inducible gene expression and environmentally regulated genes in lactic acid bacteria

    NARCIS (Netherlands)

    Kok, Jan

    1996-01-01

    Relatively recently, a number of genes and operons have been identified in lactic acid bacteria that are inducible and respond to environmental factors. Some of these genes/operons had been isolated and analysed because of their importance in the fermentation industry and, consequently, their

  15. Tackling the Relevance of Packaging in Life Cycle Assessment of Virgin Olive Oil and the Environmental Consequences of Regulation.

    Science.gov (United States)

    Navarro, Alejandra; Puig, Rita; Martí, Elena; Bala, Alba; Fullana-I-Palmer, Pere

    2018-04-12

    Production and consumption of olive oil is very important in Europe, being this product a basic element in the Mediterranean diet since long ago. The project objective is two-fold: a study of the contribution of virgin olive oils (VOOs) usual packaging to the whole life cycle of the product and a study of the environmental consequences of the Spanish Government regulation on VOO packaging. A life cycle assessment (LCA) according to ISO 14044 has been performed using the CML methodology for the impact assessment. The results show that the packaging influence varies from 2 to 300%, depending on the impact category and type of packaging (glass, tin or polyethylene terephtalate). Glass, which is related to higher quality perception by consumers, was found to be the most influencing material (due to its weight); however, this impact may be fairly reduced by applying ecodesign strategies (such as weight reduction and recycled-glass percentage increase). A new Spanish regulation on the mandatory use of non-refillable oilers in HORECA establishments (hotels, restaurants and caterings) aims to provide more quality assurance and better information to consumers; however, it was also found to mean a 74% increase in greenhouse gases emissions. This regulation was deeply discussed at European level and its application was withdraw due to consumers rejection, except for Spain. The findings of the present case study show that LCA and ecodesign should be important tools to be promoted and applied in policy making to reduce non-desirable consequences of regulation.

  16. Reconsidering the relevance of social license pressure and government regulation for environmental performance of European SMEs

    NARCIS (Netherlands)

    Graafland, Johan; Smid, Hugo

    Whereas social license pressure is held as a strong motive for the corporate social performance (CSP) of large enterprises, it is argued in literature that it will not sufficiently motivate small and medium-sized enterprises (SMEs). In this view, government regulation is the most effective way to

  17. Environmental Regulations: Impact on the United States Petroleum Exploration and Production Industry

    Science.gov (United States)

    1993-12-01

    through the following: " A permit program (NPDES) " Minimum national effluent standards for each industry "* Water quality standards "* Provisions...chromium thinner (a) Lignosufonate/Lignite Sulfomethylated tannin / chromium thinner (a) dichromate Sodium dichromate/ chromium corrosion (b) chromate...local effluent requirements. Solid wastes, such as garbage, paper, etc. should be disposed of in accordance with state solid waste regulations. Empty

  18. 78 FR 32686 - Final Supplemental Environmental Impact Statement on the Issuance of Annual Regulations...

    Science.gov (United States)

    2013-05-31

    ... special regulations. (5) Management scale for the harvest of migratory birds. We define management scale... comments in revising the document. The SEIS analyzes a range of management alternatives for addressing the... Representative, Division of Migratory Bird Management, (503) 231-6162; or Brad Bortner, Chief, Division of...

  19. Environmental light and suprachiasmatic nucleus interact in the regulation of body temperature.

    NARCIS (Netherlands)

    Scheer, F.A.J.L.; Pirovano, C.; Someren, E.J.W. van; Buijs, R.M.

    2005-01-01

    The mammalian biological clock, located in the suprachiasmatic nucleus (SCN), is crucial for circadian rhythms in physiology and behavior. However, equivocal findings have been reported on its role in the circadian regulation of body temperature. The goal of the present studies was to investigate

  20. Vehicle to Grid regulation services of electric delivery trucks: Economic and environmental benefit analysis

    International Nuclear Information System (INIS)

    Zhao, Yang; Noori, Mehdi; Tatari, Omer

    2016-01-01

    Highlights: • Potential net present revenues of electric truck based V2G regulation services are investigated. • GHG emission mitigation of V2G regulation services provided by electric trucks are quantified. • The total cost of ownership and the life-cycle GHG emissions of electric trucks are also analyzed. • V2G regulation services for electric trucks could yield considerable revenues and GHG emission savings. - Abstract: Concerns regarding the fuel costs and climate change impacts associated with petroleum combustion are among the main driving factors for the adoption of electric vehicles. Future commercial delivery truck fleets may include Battery Electric Vehicles (BEVs) and Extended Range Electric Vehicles (EREVs); in addition to savings on fuel and maintenance costs, the introduction of these grid accessible electric vehicles will also provide fleet owners with possible Vehicle to Grid (V2G) opportunities. This study investigates the potential net present revenues and greenhouse gas (GHG) emission mitigation of V2G regulation services provided by electric trucks in a typical fleet. The total cost of ownership and the life-cycle GHG emissions of electric trucks are also analyzed and compared to those of traditional diesel trucks. To account for uncertainties, possible ranges for key parameters are considered instead of only considering fixed single data values for each parameter. The results of this research indicate that providing V2G regulation services for electric trucks could yield considerable additional revenues ($20,000–50,000) and significant GHG emission savings (approximately 300 ton CO 2 ) compared to conventional diesel trucks.

  1. Environmental policy and regulation for oil exploration and shipping activities in the Barents Sea

    International Nuclear Information System (INIS)

    Futsaeter, G.

    1994-01-01

    The Barents Ses has one of the highest levels of biological production of all the world's oceans, and holds some of the largest fish stocks and concentrations of seabirds. Environmental conditions in the area make it particularly vulnerable to damage from human activities. The Norwegian Pollution Control Authority gives priority to preventive measures that can lower the probability of accidents and particular emphasis will be given to conditions attached to production licenses and controls on activities in areas that have not yet been opened for petroleum activities. Within the Arctic Environmental Protection Strategy (the Rovaniemi-process), Norway has proposed that efforts should be made to improve the protection of Arctic marine areas, and further that a working group including representatives of all the Arctic countries should assess various legal instruments and possible measures, and make recommendations for action. (author)

  2. Agri-environmental Regulation on the Back of a Data Envelopment Analysis

    OpenAIRE

    White, Benedict; Raguragavan, Jananee; Chambers, Robert G.

    2007-01-01

    A land retirement policy whereby land is taken out of agriculture and converted to natural vegetation or forestry has the potential to reduce environmental damage related to dryland salinity in Western Australia. This paper uses some recent results in the theory of directional distance functions (Chambers and Fare, 2004) to analyse alternative policy designs for a land retirement scheme. The results indicate that a fixed price scheme is inefficient compared with a first-best solution, but per...

  3. The coastal regulation zone of Goa: Oceanographic, environmental and societal perspectives

    Digital Repository Service at National Institute of Oceanography (India)

    Mascarenhas, A.

    of tourism on coasts worldwide6, the Goan coast offers an opportunity to test the use and effectiveness of coastal legislations with respect to human activity and ecosensitive coastal systems. This paper attempts to analyse issues related to the CRZ of Goa... notification5 issued under the Environment Protection Act of 1986. Its main purpose was to control, minimize and protect environmental damage to sensitive coastal stretches from unplanned human interference. The Government of India therefore declared coastal...

  4. Environmental regulation of lateral root emergence in Medicago truncatula requires the HD-Zip I transcription factor HB1.

    Science.gov (United States)

    Ariel, Federico; Diet, Anouck; Verdenaud, Marion; Gruber, Véronique; Frugier, Florian; Chan, Raquel; Crespi, Martin

    2010-07-01

    The adaptation of root architecture to environmental constraints is a major agricultural trait, notably in legumes, the third main crop worldwide. This root developmental plasticity depends on the formation of lateral roots (LRs) emerging from primary roots. In the model legume Medicago truncatula, the HD-Zip I transcription factor HB1 is expressed in primary and lateral root meristems and induced by salt stress. Constitutive expression of HB1 in M. truncatula roots alters their architecture, whereas hb1 TILLING mutants showed increased lateral root emergence. Electrophoretic mobility shift assay, promoter mutagenesis, and chromatin immunoprecipitation-PCR assays revealed that HB1 directly recognizes a CAATAATTG cis-element present in the promoter of a LOB-like (for Lateral Organ Boundaries) gene, LBD1, transcriptionally regulated by auxin. Expression of these genes in response to abscisic acid and auxin and their behavior in hb1 mutants revealed an HB1-mediated repression of LBD1 acting during LR emergence. M. truncatula HB1 regulates an adaptive developmental response to minimize the root surface exposed to adverse environmental stresses.

  5. Maryland Power Plant Cooling-Water Intake Regulations and their Application in Evaluation of Adverse Environmental Impact

    Directory of Open Access Journals (Sweden)

    Richard McLean

    2002-01-01

    Full Text Available Maryland’s cooling-water intake and discharge regulations, the Code of Maryland Regulations (COMAR 26.08.03, stem from Sections 316(a and (b of the Clean Water Act (CWA. COMAR 26.08.03.05 and litigative and administrative rulings stipulate that the location, design, construction, and capability of cooling-water intake structures must reflect the best technology available (BTA for minimizing adverse environmental impacts (AEIs, providing that the costs of implementing the BTA are not wholly disproportionate to the expected environmental benefits. Maryland law exempts facilities that withdraw less than 10 million gallons/day (MGD and less than 20% of stream or net flow by the intake. If not exempt, BTA must be installed if the cost of doing so is less than five times the value of fish impinged annually. Through site-specific studies and the use of a Spawning and Nursery Area of Consequence (SNAC model applied to Representative Important Species, several power plants were evaluated to determine if they have had an adverse effect on spawning and nursery areas of consequence. Examples of application of the Maryland law to a number of power plants in the state are presented, together with the outcome of their evaluation.

  6. Implications of research on endocrine disruption for the environmental risk assessment, regulation and monitoring of chemicals in the European Union

    International Nuclear Information System (INIS)

    Matthiessen, Peter; Johnson, Ian

    2007-01-01

    We assess the implications which research on endocrine disrupting chemicals (EDCs) has for the regulation of synthetic substances and for the protection of the environment, particularly under the forthcoming European Union (EU) REACH legislation. EDCs present regulatory problems inter alia because they can act additively at concentrations which are individually harmless, and they may have non-classical dose (concentration)-response relationships at low exposure levels. Furthermore, current in vivo testing routines were not specifically designed to assess the endocrine disrupting properties of chemicals, whilst in silico and in vitro methods have only limited applicability and availability for this purpose. We need to ensure that the assessment approaches specified in the draft REACH legislation and Technical Guidance are able to evaluate EDCs efficiently. However, it must also be recognised that environmental monitoring procedures in Europe will need to be improved to detect EDCs that have evaded identification, and where appropriate, control, under REACH. - The challenges associated with the environmental risk assessment and regulation of endocrine disrupting chemicals are discussed

  7. Identifying Critical Habitat for Australian Freshwater Turtles in a Large Regulated Floodplain: Implications for Environmental Water Management

    Science.gov (United States)

    Ocock, J. F.; Bino, G.; Wassens, S.; Spencer, J.; Thomas, R. F.; Kingsford, R. T.

    2018-03-01

    Freshwater turtles face many threats, including habitat loss and river regulation reducing occupancy and contributing to population decline. Limited knowledge of hydrological conditions required to maintain viable turtle populations in large floodplain wetlands hinders effective adaptive management of environmental water in regulated rivers. We surveyed three turtle species over 4 years across the Lower Murrumbidgee River floodplain, a large wetland complex with a long history of water resource development. Using site and floodplain metrics and generalized linear models, within a Bayesian Model Averaging framework, we quantified the main drivers affecting turtle abundance. We also used a hierarchical modeling approach, requiring large sample sizes, quantifying possible environmental effects while accounting for detection probabilities of the eastern long-necked turtle ( Chelodina longicollis). The three species varied in their responses to hydrological conditions and connectivity to the main river channel. Broad-shelled turtles ( Chelodina expansa) and Macquarie River turtles ( Emydura macquarii macquarii) had restricted distributions, centered on frequently inundated wetlands close to the river, whereas the eastern long-necked turtles were more widely distributed, indicating an ability to exploit variable habitats. We conclude that turtle communities would benefit from long-term management strategies that maintain a spatiotemporal mosaic of hydrological conditions. More specifically, we identified characteristics of refuge habitats and stress the importance of maintaining their integrity during dry periods. Neighboring habitats can be targeted during increased water availability years to enhance feeding and dispersal opportunities for freshwater turtles.

  8. Evaluation 2000 and regulation and method. Release monitoring and environmental surveillance around Cea centers

    International Nuclear Information System (INIS)

    2001-06-01

    This publication counts for the year 2000 for the evaluation of liquid and gaseous radioactive effluents releases and the radioactivity levels measured in the vicinity of Cea centers, through the air, water, vegetation and milk surveillance. An analysis of the results from 1996 to 2000 allows to follow their evolution. A second booklet develops the sampling and measurement methods made on effluents in environment. It present besides the regulation applied to effluents monitoring. (N.C.)

  9. Developmental and Environmental Regulation of AaeIAP1 Transcript in Aedes aegypti

    Science.gov (United States)

    2008-01-01

    present the developmental regulation of an IAP1 homolog from Aedes aegypti (L.), AaeIAP1, the vector of yellow fever and dengue viruses, both of which...swine fever virus IAP ho- molog is a late structural polypeptide. Virology 214: 670Ð 674. Christophers, S. R. 1960. Aedes aegypti (L.) the yellow fever ...and J. Zhang. 2007. The Aedes albopictus inhibitor of apoptosis 1 gene protects verte- brate cells from bluetongue virus-induced apoptosis. In- sect

  10. Impact of environmental regulations on control of copper ion concentration in the DIII-D cooling water system

    International Nuclear Information System (INIS)

    Gootgeld, A.M.

    1993-10-01

    Tokamaks and industrial users are faced with the task of maintaining closed-loop, low conductivity, low impurity, cooling water systems. Operating these systems concentrates the impurities in the water requiring subsequent disposal. Environmental regulations are making this increasingly difficult. This paper will discuss the solution to the problem of removing and disposing of copper ions in the DIII-D low conductivity water system. Since the commissioning of the Doublet facility, the quality of the water in the 3000 gpm system that cools the DIII-D vacuum vessel coils, power supplies and auxiliary heating components has been controlled with mixed-bed ion exchangers. Low ion levels, particularly copper, are required to operate this equipment. In early 1992, the company that leases and regenerates DIII-D ion exchangers said they no longer can accept these resin beds for regeneration due to the level of copper ion on the resin. This change in policy, a change that has been adopted throughout their industry, was necessary to assure that the Metropolitan Sewerage System of the City of San Diego stays in compliance with State of California regulations and EPA-mandated national pretreatment standards and regulations. A cost effective solution was implemented which utilizes a reverse osmosis filtration system with the ion exchangers for make-up water. Levels of copper ion disposed to the sewer are in compliance with government standards. These measures have thus far proved effective in maintaining low conductivity and overall good quality cooling water. Specifically, this paper discusses DIII-D deionized cooling water quality requirements and an affective means to meet these requirements in order to be in compliance with government regulations for copper ion disposal. The problems discussed, the alternatives considered and the approach taken would be readily applicable to any deionized cooling water system containing copper where EPA standards and regulations are mandated

  11. Management Innovation for Environmental Sustainability in Seaports: Managerial Accounting Instruments and Training for Competitive Green Ports beyond the Regulations

    Directory of Open Access Journals (Sweden)

    Assunta Di Vaio

    2018-03-01

    Full Text Available In the last 30 years, environmental sustainability has been receiving increasing attention by scholars and operators. All the seaport stakeholders, including port authorities (PAs, policy-makers, port users, any port stakeholders, and local communities, must invest substantial resources to achieve high competitiveness with respect of the environment. Drawing from the extant regulations system and conducting a deep review of the main contributions on the phenomenon, this conceptual study suggests managerial accounting instruments and training, which are still under-researched, as effective measures for enforcing and encouraging green port development. This three-step study consists of a systematic review of the regulatory frameworks and literature on the phenomenon, and an outline of the gap of the legislative framework and research, from a management innovation perspective, where effective managerial practices for environmental sustainability are not successfully suggested and implemented within seaports. On the one hand, the Balanced Scorecard and Tableau de Bord are identified and proposed as managerial accounting instruments for assessing, monitoring, measuring, controlling, and reporting the organizational processes of port players, mainly PAs, for developing competitive green ports. On the other hand, training has been suggested to educate and guide the human resources at all organizational levels within seaports, for supporting and developing awareness and behavioral attitudes in the direction of environmental sustainability.

  12. Public choice and environmental regulation. Tradable permit systems in the United States and CO{sub 2} taxation in Europe

    Energy Technology Data Exchange (ETDEWEB)

    Tinggaard Svendsen, G. [The Aarhus School of Business, Dept. of Economics (Denmark)

    1996-05-01

    The thesis raises the question whether taxation or permit markets are most cost-effective in environmental regulation. The general answer given by the author is that a combination of these two economic control measures would minimize the cost of CO{sub 2} abatement. A `grandfather` permit market can prove to be more cost-effective than a CO{sub 2} tax with regard to organized interests: first because in the near future both industry and electric utilities will experience a growing competition in the common market, secondly because permit markets offer essential results to the environmental organizations. Taxation can come in useful where interests are poorly organized, like in households and transportation sector. Taxes can force environmental improvements through as well as eliminate tax distortion due to income tax reduction. Thus the state has a strong economic interest in development of economic incentive measures, increasing production and exports. The use of a comparative method and the rationale for transferring US experience to European ground is considered. CO{sub 2} taxation in Denmark and the failed attempt to introduce a common CO{sub 2} tax in the EU is analyzed. Perspectives of a CO{sub 2} market on an EU scale and global scale are discussed. (EG) 139 refs.

  13. Public choice and environmental regulation. Tradable permit systems in the United States and CO2 taxation in Europe

    International Nuclear Information System (INIS)

    Tinggaard Svendsen, G.

    1996-05-01

    The thesis raises the question whether taxation or permit markets are most cost-effective in environmental regulation. The general answer given by the author is that a combination of these two economic control measures would minimize the cost of CO 2 abatement. A 'grandfather' permit market can prove to be more cost-effective than a CO 2 tax with regard to organized interests: first because in the near future both industry and electric utilities will experience a growing competition in the common market, secondly because permit markets offer essential results to the environmental organizations. Taxation can come in useful where interests are poorly organized, like in households and transportation sector. Taxes can force environmental improvements through as well as eliminate tax distortion due to income tax reduction. Thus the state has a strong economic interest in development of economic incentive measures, increasing production and exports. The use of a comparative method and the rationale for transferring US experience to European ground is considered. CO 2 taxation in Denmark and the failed attempt to introduce a common CO 2 tax in the EU is analyzed. Perspectives of a CO 2 market on an EU scale and global scale are discussed. (EG) 139 refs

  14. Regulation of migration in Mythimna separata (Walker) in China: a review integrating environmental, physiological, hormonal, genetic, and molecular factors.

    Science.gov (United States)

    Jiang, Xingfu; Luo, Lizhi; Zhang, Lei; Sappington, Thomas W; Hu, Yi

    2011-06-01

    Each year the Mythimna separate (Walker), undertakes a seasonal, long-distance, multigeneration roundtrip migration between southern and northern China. Despite its regularity, the decision to migrate is facultative, and is controlled by environmental, physiological, hormonal, genetic, and molecular factors. Migrants take off on days 1 or 2 after eclosion, although the preoviposition period lasts ≈7 d. The trade-offs among the competing physiological demands of migration and reproduction are coordinated in M. separata by the "oogenesis-flight syndrome." Larvae that experience temperatures above or below certain thresholds accompanied by appropriate humidity, short photoperiod, poor nutrition, and moderate density tend to develop into migrants. However, there is a short window of sensitivity within 24 h after adult eclosion when migrants can be induced to switch to reproductive residents if they encounter extreme environmental factors including starvation, low temperature and long photoperiod. Juvenile hormone (JH) titer is low before migration but high titers are associated with termination of migratory behavior and the switch to reproduction. Early release of JH by the corpora allata in environmentally stressed 1-d old adults, otherwise destined by larval conditions to be migrants, switches them to residents. Offspring inherit parental additive genetic effects governing migratory behavior. However, they also retain flexibility in expression of both flight and reproductive life history traits. The insect neuropeptide, allatotropin, which activates corpora allata to synthesize JH, controls adult flight and reproduction. Future research directions to better understand regulation of migration in this species are discussed.

  15. Acid-base regulation in tadpoles of Rana catesbeiana exposed to environmental hypercapnia

    DEFF Research Database (Denmark)

    Busk, Morten; Larsen, Erik Hviid; Jensen, Frank B.

    1997-01-01

    Tadpoles of Rana catesbeiana were exposed to different levels of environmental hypercapnia. The acid-base regulatory response differed from that in adult amphibians in showing a high degree of pH compensation in the extracellular fluid (65-85%) and complete compensation in the intracellular fluid......). It is suggested that the large bicarbonate efflux from the animal is a consequence of the dissolution of CaCO3 stores and the delayed adjustment of bicarbonate-retaining mechanisms. Re-exposure of tadpoles to hypercapnia after 1-3 weeks of normocapnic recovery only affected transepithelial fluxes of acid-base...

  16. Are Dutch residents ready for a more stringent policy to enhance the energy performance of their homes?

    International Nuclear Information System (INIS)

    Middelkoop, Manon van; Vringer, Kees; Visser, Hans

    2017-01-01

    Investments in the energy performance of houses offer good prospects for reducing energy consumption and CO 2 emissions. However, people are not easily convinced of the need to take measures to improve the energy performance of their houses, even when financial benefits outweigh the costs. This article analyses the factors that influence the decision for improving the energy performance of existing homes, including policy instruments. Subsequently, the article provides policy suggestions on how to stimulate energy performance improvements. Both owners and tenants (50–70%) support government policy on energy performance improvements to existing homes. Nevertheless, people also have strong feelings of autonomy regarding their homes. Our results underline the importance of well-informed and competent decision-makers. Introducing the use of Energy Performance Certificates (EPCs) into the tax system for energy and residential buildings might therefore be an effective way to increase the interest of owners in the EPC, improve the use and effect of this informative instrument, and make the first step towards bridging the tension between autonomy and more stringent instruments.

  17. Shifting trends: detecting environmentally mediated regulation in long-lived marine vertebrates using time-series data.

    Science.gov (United States)

    McMahon, Clive R; Bester, Marthán N; Hindell, Mark A; Brook, Barry W; Bradshaw, Corey J A

    2009-02-01

    Assessing the status and trends in animal populations is essential for effective species conservation and management practices. However, unless time-series abundance data demonstrate rapid and reliable fluctuations, objective appraisal of directionality of trends is problematic. We adopted a multiple-working hypotheses approach based on information-theoretic and Bayesian multi-model inference to examine the population trends and form of intrinsic regulation demonstrated by a long-lived species, the southern elephant seal. We also determined the evidence for density dependence in 11 other well-studied marine mammal species. (1) We tested the type of population regulation for elephant seals from Marion Island (1986-2004) and from 11 other marine mammal species, and (2) we described the trends and behavior of the 19-year population time series at Marion Island to identify changes in population trends. We contrasted five plausible trend models using information-theoretic and Bayesian-inference estimates of model parsimony. Our analyses identified two distinct phases of population growth for this population with the inflexion occurring in 1998. Thus, the population decreased between 1986 and 1997 (-3.7% per annum) and increased between 1997 and 2004 (1.9% per annum). An index of environmental stochasticity, the Southern Oscillation Index, explained some of the variance in r and N. We determined analytically that there was good evidence for density dependence in the Marion Island population and that density dependence was widespread among marine mammal species (67% of species showed evidence for population regulation). This approach demonstrates the potential functionality of a relatively simple technique that can be applied to short time series to identify the type of regulation, and the uncertainty associated with the phenomenon, operating in populations of large mammals.

  18. Gene expression of thyrotropin- and corticotrophin-releasing hormones is regulated by environmental salinity in the euryhaline teleost Sparus aurata.

    Science.gov (United States)

    Ruiz-Jarabo, Ignacio; Martos-Sitcha, J A; Barragán-Méndez, C; Martínez-Rodríguez, G; Mancera, J M; Arjona, F J

    2018-04-01

    In euryhaline teleosts, the hypothalamus-pituitary-thyroid and hypothalamus-pituitary-interrenal axes (HPT and HPI, respectively) are regulated in response to environmental stimuli such as salinity changes. However, the molecular players participating in this physiological process in the gilthead seabream (Sparus aurata), a species of high value for aquaculture, are still not identified and/or fully characterized in terms of gene expression regulation. In this sense, this study identifies and isolates the thyrotropin-releasing hormone (trh) mRNA sequence from S. aurata, encoding prepro-Trh, the putative factor initiating the HPT cascade. In addition, the regulation of trh expression and of key brain genes in the HPI axis, i.e., corticotrophin-releasing hormone (crh) and corticotrophin-releasing hormone-binding protein (crhbp), was studied when the osmoregulatory status of S. aurata was challenged by exposure to different salinities. The deduced amino acid structure of trh showed 65-81% identity with its teleostean orthologs. Analysis of the tissue distribution of gene expression showed that trh mRNA is, though ubiquitously expressed, mainly found in brain. Subsequently, regulation of gene expression of trh, crh, and crhbp was characterized in fish acclimated to 5-, 15-, 40-, and 55-ppt salinities. In this regard, the brain gene expression pattern of trh mRNA was similar to that found for the crh gene, showing an upregulation of gene expression in seabream acclimated to the highest salinity tested. Conversely, crhbp did not change in any of the groups tested. Our results suggest that Trh and Crh play an important role in the acclimation of S. aurata to hypersaline environments.

  19. Designing Green Taxes in a Political Context: From Optimal to Feasible Environmental Regulation

    DEFF Research Database (Denmark)

    Daugbjerg, Carsten; Svendsen, Gert Tinggaard

    2003-01-01

    How should green taxation be designed? We argue that to design green taxes which are high enough to have the desired incentive effects, tax revenues must be reimbursed, either by earmarking them for environmental subsidies or by reducing other taxes directed at industry. If green tax schemes can...... be designed this way, industry will have little incentive to mobilise strong opposition to green taxation. However, in practice, the requirement of reimbursement may be difficult to fulfil because, with few exceptions, polluting industries are not homogeneous. This means that reimbursement will redistribute...... financial resources within industry and thus create winners and losers. Still, we demonstrate how green taxation can be used in heterogeneous industries which can be created by operating separate tax schemes for each branch of industry....

  20. Designing Green Taxes in a Political Context: From Optimal to Feasible Environmental Regulation

    DEFF Research Database (Denmark)

    Daugbjerg, Carsten; Svendsen, Gert Tinggaard

    2001-01-01

    How should green taxation be designed so that it accommodates producer interests? We argue that to design green taxes which are high enough to have the desired incentive effects, tax revenues must be reimbursed, either by earmarking them for environmental subsidies or by reducing other taxes...... directed at industry. If green tax schemes can be designed this way, industry will have little incentive to mobilise strong opposition to green taxation. However, in practice, the requirement of reimbursement may be difficult to fulfil because, with few exceptions, polluting industries are not homogeneous....... This means that reimbursement will redistribute financial resources within industry and thus create winners and losers. Still, green taxes can be used in heterogeneous industries which can be created by operating separate tax schemes for each branch of industry. The Danish case of pesticide taxation...

  1. Modelling the interactions between regional farming structure, nitrogen losses and environmental regulation

    DEFF Research Database (Denmark)

    Happe, Kathrin; Hutchings, Nick; Dalgaard, Tommy

    2011-01-01

    by one livestock unit. Substantial changes in the structure of agricultural production were shown for both scenarios. The effect on the regional nitrogen surpluses was predicted to differ between scenarios and the contribution of the different farm types to change with time. Predicted ammonia emission......Changes in the structure of agriculture are known to affect emissions of environmental pollutants from agriculture. Such changes are often driven by structural changes in agricultural production, so structural changes are likely to have indirect effects on emissions. In a pilot study, we consider...... how linking two complementary simulation models might be used to explore these effects. The agent-based AgriPoliS model was used to simulate the structural dynamics of agricultural production. The results from AgriPoliS were passed via a number of intermediate models to the Farm-N model, which...

  2. United States import safety, environmental health, and food safety regulation in China.

    Science.gov (United States)

    Nyambok, Edward O; Kastner, Justin J

    2012-01-01

    China boasts a rapidly growing economy and is a leading food exporter. Since China has dominated world export markets in food, electronics, and toys, many safety concerns about Chinese exports have emerged. For example, many countries have had problems with Chinese food products and food-processing ingredients. Factors behind food safety and environmental health problems in China include poor industrial waste management, the use of counterfeit agricultural inputs, inadequate training of farmers on good farm management practices, and weak food safety laws and poor enforcement. In the face of rising import safety problems, the U.S. is now requiring certification of products and foreign importers, pursuing providing incentives to importers who uphold good safety practices, and considering publicizing the names of certified importers.

  3. Proceedings: An international workshop on offshore lease abandonment and platform disposal: Technology, regulation, and environmental effects

    Energy Technology Data Exchange (ETDEWEB)

    Pulsipher, A. [ed.] [Louisiana State Univ., Baton Rouge, LA (United States). Center for Energy Studies

    1997-03-01

    This Proceedings volume includes papers prepared for an international workshop on lease abandonment and offshore platform disposal. The workshop was held April 15, 16, and 17, 1996, in New Orleans, Louisiana. Included in the volume are several plenary speeches and issue papers. prepared by six working groups, who discussed: Abandoning Wells; Abandoning Pipelines; Removing Facilities; Site Clearance; Habitat Management, Maintenance, and Planning; and Regulation and Policy. Also included are an introduction, an afterword (reprinted with the permission of its author, John Lohrenz), and, as Appendix C, the complete report of the National Research Council Marine Boards An Assessment of Techniques for Removing Fixed Offshore Structures, around which much of the discussion at the workshop was organized. Short biographies of many speakers, organizers, and chairpersons are included as Appendix A. Appendix B is a list of conference participants. Selected papers have been processes separately for inclusion in the Energy Science and Technology database.

  4. The impact of U.S. environmental regulations on fuel quality

    International Nuclear Information System (INIS)

    Strauss, K.H.; Dukek, W.G.

    1993-01-01

    The amendments to the Clean Air Act passed in 1990 focused attention on the emissions from mobile sources, such as automobiles and trucks, as they degrade air quality, particularly in urban areas. In legislating the 1990 amendments, it was recognized that a change in gasoline composition could have as great an effect on improved air quality as design changes in the automobile itself. Without lead available to meet vehicle octane requirements, the refiners increased the use of isoparaffinic and aromatic streams as blending components and began a search for replacement octane enhancers. More reforming units were added in refineries to produce streams of high aromatic content, a step that fortuitously produced more hydrogen gas for treating other products, such as jet fuel and heavier middle distillates, to reduce sulfur content and improve stability. The close relationship between motor gasoline and the quality of other products explains why the advent of reformulated gasoline in the 1990s is viewed with concern by refiners, particularly because the government has now decided to also mandate improvements in diesel fuel quality that will require much of the hydrogen that was counted on to treat jet fuels. As a consequence, the fuel subcommittees of Committee D-2 on Petroleum Products decided that the best forum for highlighting the interrelationships between all major fuels and the impending regulations to improve air quality was a symposium. The symposium began with the latest thinking of the Federal and State governments on air quality regulations and results were then presented from the industry Auto/Oil Air Quality Research Program. The impact of these pending changes on petroleum refining was then discussed. Later, the impact on fuel users for various applications and the effect on ASTM standards was presented. Papers have been processed separately for inclusion on the data base

  5. Environmental regulation of the long polar fimbriae 2 of enterohemorrhagic Escherichia coli O157:H7.

    Science.gov (United States)

    Arenas-Hernández, Margarita M; Rojas-López, Maricarmen; Medrano-López, Abraham; Nuñez-Reza, Karen J; Puente, José Luis; Martínez-Laguna, Ygnacio; Torres, Alfredo G

    2014-08-01

    The molecular mechanisms controlling expression of the long polar fimbriae 2 (Lpf2) of enterohemorrhagic Escherichia coli (EHEC) O157:H7 were evaluated. Primer extension was used to locate the lpfA2 transcriptional start site in EHEC strain EDL933 at 171 bp upstream of the lpfA2 start codon. Semi-quantitative RT-PCR demonstrated that the highest lpfA2 expression occurs between an OD600 of 1.0 and 1.2 in DMEM at pH 6.5 and 37 °C. The level of lpfA2 transcription at OD600 1.2 and pH 6.5 was four times greater than that at pH 7.2. Although lpfA2 expression was decreased under iron-depleted conditions, its expression was increased in a ferric-uptake-regulator (Fur) mutant strain. The lpfA2 transcript was 0.7 and 2 times more abundant in wt EHEC grown in DMEM pH 6.5 plus iron and MacConkey broth at 25 °C, respectively, than in DMEM at pH 6.5. The lpf2 expression in DMEM pH 6.5 plus iron and bile salts was 2.7 times more abundant than baseline conditions. Further, transcription in the EDL933∆fur was 0.6 and 0.8 times higher as compared with the wt strain grown in DMEM pH 6.5 plus iron and MacConkey broth, respectively. Electrophoretic mobility shift assays showed that purified Fur interacts with the lpf2 regulatory region, indicating that Fur repression is exerted by direct binding to the promoter region. In summary, we demonstrated that the EHEC lpf2 operon is regulated in response to temperature, pH, bile salts and iron, during the exponential phase of growth, and is controlled by Fur. © 2014 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.

  6. Stringently Defined Otitis Prone Children Demonstrate Deficient Naturally Induced Mucosal Antibody Response toMoraxella catarrhalisProteins.

    Science.gov (United States)

    Ren, Dabin; Murphy, Timothy F; Lafontaine, Eric R; Pichichero, Michael E

    2017-01-01

    Moraxella catarrhalis ( Mcat ) is a prominent mucosal pathogen causing acute otitis media (AOM). We studied Mcat nasopharyngeal (NP) colonization, AOM frequency and mucosal antibody responses to four vaccine candidate Mcat proteins: outer membrane protein (OMP) CD, oligopeptide permease (Opp) A, hemagglutinin (Hag), and Pilin A clade 2 (PilA2) from stringently defined otitis prone (sOP) children, who experience the greatest burden of disease, compared to non-otitis prone (NOP) children. sOP children had higher NP colonization of Mcat (30 vs. 22%, P  = 0.0003) and Mcat -caused AOM rates (49 vs. 24%, P  P  P  = 0.018), Hag (IgG and IgA, both P  P  P  = 0.039) and PilA2 ( P  = 0.0076), and IgA to OMP CD ( P  = 0.010), OppA ( P  = 0.030), and PilA2 ( P  = 0.043) were associated with lower carriage of Mcat in NOP but not sOP children. Higher levels of mucosal IgG to OMP CD ( P  = 0.0070) and Hag ( P  = 0.0003), and IgA to Hag ( P  = 0.0067) at asymptomatic colonization than those at onset of AOM were associated with significantly lower rate of Mcat NP colonization progressing to AOM in NOP compared to sOP children (3 vs. 26%, P  NP colonization and NP colonization progressing to Mcat -caused AOM. Enhancing Mcat antigen-specific mucosal immune responses to levels higher than achieved by natural exposure will be necessary to prevent AOM in sOP children.

  7. Stringent constraints on the dark matter annihilation cross section from subhalo searches with the Fermi Gamma-Ray Space Telescope

    Energy Technology Data Exchange (ETDEWEB)

    Berlin, Asher; Hooper, Dan

    2014-01-01

    The dark matter halo of the Milky Way is predicted to contain a very large number of smaller subhalos. As a result of the dark matter annihilations taking place within such objects, the most nearby and massive subhalos could appear as point-like or spatially extended gamma-ray sources, without observable counterparts at other wavelengths. In this paper, we use the results of the Aquarius simulation to predict the distribution of nearby subhalos, and compare this to the characteristics of the unidentified gamma-ray sources observed by the Fermi Gamma-Ray Space Telescope. Focusing on the brightest high latitude sources, we use this comparison to derive limits on the dark matter annihilation cross section. For dark matter particles lighter than ~200 GeV, the resulting limits are the strongest obtained to date, being modestly more stringent than those derived from observations of dwarf galaxies or the Galactic Center. We also derive independent limits based on the lack of unidentified gamma-ray sources with discernible spatial extension, but these limits are a factor of ~2-10 weaker than those based on point-like subhalos. Lastly, we note that four of the ten brightest high-latitude sources exhibit a similar spectral shape, consistent with 30-60 GeV dark matter particles annihilating to b quarks with an annihilation cross section on the order of sigma v ~ (5-10) x 10^-27 cm^3/s, or 8-10 GeV dark matter particles annihilating to taus with sigma v ~ (2.0-2.5) x 10^-27 cm^3/s.

  8. Designing green taxes in a political context: From optimal to feasible environmental regulation

    International Nuclear Information System (INIS)

    Daugbjerg, C.; Tinggaard Svendsen, G.

    2001-01-01

    How should green taxation be designed so that it accommodates producer interests? We argue that to design green taxes which are high enough to have the desired incentive effects, tax revenues must be reimbursed, either by earmarking them for environmental subsidies or by reducing other taxes directed at industry. If green tax schemes can be designed this way, industry will have little incentive to mobilise strong opposition to green taxation. However, in practice, the requirement of reimbursement may be difficult to fulfil because, with few exceptions, polluting industries are not homogeneous. This means that reimbursement will redistribute financial resources within industry and thus create winners and losers. Still, green taxes can be used in heterogeneous industries which can be created by operating separate tax schemes for each branch of industry. The Danish case of pesticide taxation demonstrates that relatively high tax levels can be implemented if an equal relationship between the tax object and the object determining the level of refunds exists throughout the sector. This means that revenues can be reimbursed without creating redistribution within producer communities. (au)

  9. Designing green taxes in a political context: From optimal to feasible environmental regulation

    Energy Technology Data Exchange (ETDEWEB)

    Daugbjerg, C.; Tinggaard Svendsen, G.

    2001-07-01

    How should green taxation be designed so that it accommodates producer interests? We argue that to design green taxes which are high enough to have the desired incentive effects, tax revenues must be reimbursed, either by earmarking them for environmental subsidies or by reducing other taxes directed at industry. If green tax schemes can be designed this way, industry will have little incentive to mobilise strong opposition to green taxation. However, in practice, the requirement of reimbursement may be difficult to fulfil because, with few exceptions, polluting industries are not homogeneous. This means that reimbursement will redistribute financial resources within industry and thus create winners and losers. Still, green taxes can be used in heterogeneous industries which can be created by operating separate tax schemes for each branch of industry. The Danish case of pesticide taxation demonstrates that relatively high tax levels can be implemented if an equal relationship between the tax object and the object determining the level of refunds exists throughout the sector. This means that revenues can be reimbursed without creating redistribution within producer communities. (au)

  10. Management, regulation and environmental impacts of nitrogen fertilization in Northwestern Europe under the Nitrates Directive

    DEFF Research Database (Denmark)

    van Grinsven, H.; ten Berge, H.; Dalgaard, Tommy

    2012-01-01

    Implementation of the Nitrates Directive (NiD) and its environmental impacts were compared for member states in the Northwest of the European Union (Ireland, UK, Denmark, The Netherlands, Belgium, Northern France and Germany). The main sources of data were national reports for the third reporting......D remains an important piece of legislation for protecting drinking water quality in regions with many private or small public production facilities and controlling aquatic eutrophication from agricultural sources....... is a major contribution to the decrease of the soil N balance (N surplus), particularly in Belgium, Denmark, Ireland, The Netherlands and the UK. This decrease is accompanied by a modest decrease of nitrate concentrations since 2000 in fresh surface waters in most countries. This decrease is less prominent...... and tenacious exceedance of the water quality standards. On average the gross N balance in 2008 for the seven member states in EUROSTAT and in national reports was about 20 kg N ha−1 lower than by MITERRA. The major cause is higher estimates of N removal in national reports which can amount to more than 50kg N...

  11. Management, regulation and environmental impacts of nitrogen fertilization in northwestern Europe under the Nitrates Directive

    DEFF Research Database (Denmark)

    van Grinsven, H.J.M.; ten Berge, H.F.M.; Dalgaard, Tommy

    2012-01-01

    Implementation of the Nitrates Directive (NiD) and its environmental impacts were compared for member states in the northwest of the European Union (Ireland, United Kingdom, Denmark, the Netherlands, Belgium, Northern France and Germany). The main sources of data were national reports for the thi...... Commission and its member states, as the NiD remains an important piece of legislation for protecting drinking water quality in regions with many private or small public production facilities and controlling aquatic eutrophication from agricultural sources....... 1995 is a major contribution to the decrease of the soil N balance (N surplus), particularly in Belgium, Denmark, Ireland, the Netherlands and the United Kingdom. This decrease is accompanied by a modest decrease of nitrate concentrations since 2000 in fresh surface waters in most countries...... leaching fractions to groundwater and tenacious exceedance of the water quality standards. On average the gross N balance in 2008 for the seven member states in EUROSTAT and in national reports was about 20 kgNha-1 yr-1 lower than by MITERRA. The major cause is higher estimates of N removal in national...

  12. Petroleum movements and investments in the refining industry: The impact of worldwide environmental regulations

    International Nuclear Information System (INIS)

    Guariguata U., G.

    1995-01-01

    Since the enactment of the US Clean Air Act Amendments of 1990, the worldwide refining industry has aligned itself to become increasing attuned to the future well-being of the environment. Refiners must now develop strategies which address careful selection of crude slates, significant increases and changes in product movements, and upgrading of facilities to meet growing demand--in short, strategies which allow them to make substantial increases in capital investments. The objective of this paper is to determine the regional capital investments refiners must make in order to comply with environmental legislation. The methodology in making this determination was founded on a comprehensive analysis of worldwide petroleum supply/demand and distribution patterns for the coming five years, and included evaluation of a set of linear programming (LP) models based on forecasts for regional product demands and projections of regional specifications. The models considered two scenarios, in which either (1) refinery expansion occurs chiefly in the market consuming regions, or (2) crude producers take control of incremental crude volumes and further expand their planned refining projects and the marketing of refined products. The results of these models, coupled with an understanding of geopolitical situations and economic analyses, provided estimates for capital expenditures for the coming decade. In specific, the following issues were addressed, and are discussed in this paper: refined product trade outlook; crude supply; crude quality; shipping; and capital investments

  13. Hovering in the heat: effects of environmental temperature on heat regulation in foraging hummingbirds.

    Science.gov (United States)

    Powers, Donald R; Langland, Kathleen M; Wethington, Susan M; Powers, Sean D; Graham, Catherine H; Tobalske, Bret W

    2017-12-01

    At high temperature (greater than 40°C) endotherms experience reduced passive heat dissipation (radiation, conduction and convection) and increased reliance on evaporative heat loss. High temperatures challenge flying birds due to heat produced by wing muscles. Hummingbirds depend on flight for foraging, yet inhabit hot regions. We used infrared thermography to explore how lower passive heat dissipation during flight impacts body-heat management in broad-billed ( Cynanthus latirostris , 3.0 g), black-chinned ( Archilochus alexandri , 3.0 g), Rivoli's ( Eugenes fulgens , 7.5 g) and blue-throated ( Lampornis clemenciae , 8.0 g) hummingbirds in southeastern Arizona and calliope hummingbirds ( Selasphorus calliope , 2.6 g) in Montana. Thermal gradients driving passive heat dissipation through eye, shoulder and feet dissipation areas are eliminated between 36 and 40°C. Thermal gradients persisted at higher temperatures in smaller species, possibly allowing them to inhabit warmer sites. All species experienced extended daytime periods lacking thermal gradients. Broad-billed hummingbirds lacking thermal gradients regulated the mean total-body surface temperature at approximately 38°C, suggesting behavioural thermoregulation. Blue-throated hummingbirds were inactive when lacking passive heat dissipation and hence might have the lowest temperature tolerance of the four species. Use of thermal refugia permitted hummingbirds to tolerate higher temperatures, but climate change could eliminate refugia, forcing distributional shifts in hummingbird populations.

  14. External Knowledge Sourcing and Green Innovation Growth with Environmental and Energy Regulations: Evidence from Manufacturing in China

    Directory of Open Access Journals (Sweden)

    Jian Hou

    2017-02-01

    Full Text Available This paper adopts the slacks-based measure-directional distance function (SBM-DDF, 2009 method for deriving the “Green Innovation Growth” rates of 28 manufacturing industries in China. The results indicate that the overall level of green innovation growth in China’s manufacturing is relatively low, with a declining trend. The tradeoffs among energy, environment and economy are rather sharp, and the “Porter Effect (1995” (environmental regulation will promote green technology innovation is not currently realized quickly in manufacturing. These evaluations imply an unsustainable development model in China, with significant differences among industries. By using a dynamic panel threshold model and employing an industry-level panel dataset for 2008–2014, we show that external knowledge sourcing has a significant negative impact on green innovation growth but with different constraints on R&D levels among industries. With the strengthening of R&D levels, gradually surpassing “critical mass”, the negative role of external knowledge sourcing in driving this mechanism becomes smaller and smaller; it has a non-linear relationship with the “threshold effect”. Consequently, we provide insights into the relationship among energy consumption, environmental pollution and technology innovation, and show how the heterogeneity of the R&D threshold affects differences in external knowledge sourcing and green innovation growth. These insights lead to a better understanding of the driving force, realizing path and policy design for green innovation growth.

  15. Functional regulation of Pb-Ti/MoS2 composite coatings for environmentally adaptive solid lubrication

    Science.gov (United States)

    Ren, Siming; Li, Hao; Cui, Mingjun; Wang, Liping; Pu, Jibin

    2017-04-01

    The lubrication of molybdenum disulfide coatings has commonly been limited by the application environments, for instance, the crystal MoS2 are easily affected by water to form MoO3 that causes a higher friction coefficient and short lifetime. Therefore, to improve the tribolgical performance of MoS2 in high humidity condition, the co-doped Pb-Ti/MoS2 composite coatings are deposited by unbalanced magnetron sputtering system. The design of the co-doping elements in MoS2-based coatings can not only maintain the characteristic of low humidity-sensitivity as the Ti/MoS2 coating but also improve the mechanical properties and tribological performance of coatings as a comparison with single-doped ones. Moreover, the ultra-low friction coefficient with a minimum value of 0.006 under the vacuum condition is achieved for Pb-Ti/MoS2 composite coating containing about 4.6 at.% Pb, depending on the densification structure of coating. Intriguingly, the wear behaviours of Pb-Ti/MoS2 composite coatings are in accordance with the variation in H/E (hardness to the elastic modulus) ratio that the coating with higher H/E exhibits lower wear rate. These results demonstrate that the lubricating properties of MoS2 coatings in both humid environment and vacuum condition can be achieved through the Pb and Ti co-doped, which is of great significant for developing MoS2 coatings as the environmentally adaptive lubricants.

  16. Compliance of the Savannah River Site D-Area cooling system with environmental regulations

    Energy Technology Data Exchange (ETDEWEB)

    Specht, W.L.; Mackey, H.E.; Paller, M.H.; Wike, L.D.; Wilde, E.W. (eds.)

    1990-08-01

    This document presents information relating to a demonstration under Section 316(a) of the Clean Water Act for the 400-D Area cooling system at the Savannah River Site (SRS) near Aiken, South Carolina. The demonstration was mandated because the National Pollution Discharge Elimination System (NPDES) permit for SRS (SC0000175), granted on January 1, 1984, specified in-stream temperature limits in SRS streams of 32.2{degree}C and a {Delta}T limit of 2.8{degree}C above ambient. To achieve compliance with in-stream temperature limits, the Department of Energy (DOE) and the South Carolina Department of Health and Environmental Control (SCDHEC) entered into a Consent Order (84-4-W) which temporarily superseded the temperature requirements and identified a process for attaining compliance. The preferred option for achieving thermal compliance in Beaver Dam Creek consisted of increased flow, with mixing of the raw water basin overflow with the cooling water discharge during the summer months. Although this action can achieve instream temperatures of less than 32.2{degree}C, {Delta}T's still exceed 2.8{degree}C. Therefore, a 316 (a) Demonstration was initiated to determine whether a balanced indigenous biological community can be supported in the receiving stream with {Delta}T's in excess of 2.8{degree}C. A Biological Monitoring Program for Beaver Dam Creek was approved by SCDHEC in June 1988 and implemented in September 1988. The program monitored the water quality, habitat formers, zooplankton, macroinvertebrates, fish, other vertebrate wildlife and threatened and endangered species in Beaver Dam Creek for an 18-month period (September 1988-February 1990). This document summarizes information collected during the monitoring program and evaluates the data to determine whether Beaver Dam Creek presently supports a balanced indigenous biological community. 97 refs., 32 figs., 51 tabs.

  17. The Biochemistry of Sensing: Enteric Pathogens Regulate Type III Secretion in Response to Environmental and Host Cues.

    Science.gov (United States)

    De Nisco, Nicole J; Rivera-Cancel, Giomar; Orth, Kim

    2018-01-16

    Enteric pathogens employ sophisticated strategies to colonize and infect mammalian hosts. Gram-negative bacteria, such as Escherichia coli , Salmonella , and Campylobacter jejuni , are among the leading causes of gastrointestinal tract infections worldwide. The virulence strategies of many of these Gram-negative pathogens rely on type III secretion systems (T3SSs), which are macromolecular syringes that translocate bacterial effector proteins directly into the host cytosol. However, synthesis of T3SS proteins comes at a cost to the bacterium in terms of growth rate and fitness, both in the environment and within the host. Therefore, expression of the T3SS must be tightly regulated to occur at the appropriate time and place during infection. Enteric pathogens have thus evolved regulatory mechanisms to control expression of their T3SSs in response to specific environmental and host cues. These regulatory cascades integrate multiple physical and chemical signals through complex transcriptional networks. Although the power of bacterial genetics has allowed elucidation of many of these networks, the biochemical interactions between signal and sensor that initiate the signaling cascade are often poorly understood. Here, we review the physical and chemical signals that Gram-negative enteric pathogens use to regulate T3SS expression during infection. We highlight the recent structural and functional studies that have elucidated the biochemical properties governing both the interaction between sensor and signal and the mechanisms of signal transduction from sensor to downstream transcriptional networks. Copyright © 2018 De Nisco et al.

  18. The Biochemistry of Sensing: Enteric Pathogens Regulate Type III Secretion in Response to Environmental and Host Cues

    Directory of Open Access Journals (Sweden)

    Nicole J. De Nisco

    2018-01-01

    Full Text Available Enteric pathogens employ sophisticated strategies to colonize and infect mammalian hosts. Gram-negative bacteria, such as Escherichia coli, Salmonella, and Campylobacter jejuni, are among the leading causes of gastrointestinal tract infections worldwide. The virulence strategies of many of these Gram-negative pathogens rely on type III secretion systems (T3SSs, which are macromolecular syringes that translocate bacterial effector proteins directly into the host cytosol. However, synthesis of T3SS proteins comes at a cost to the bacterium in terms of growth rate and fitness, both in the environment and within the host. Therefore, expression of the T3SS must be tightly regulated to occur at the appropriate time and place during infection. Enteric pathogens have thus evolved regulatory mechanisms to control expression of their T3SSs in response to specific environmental and host cues. These regulatory cascades integrate multiple physical and chemical signals through complex transcriptional networks. Although the power of bacterial genetics has allowed elucidation of many of these networks, the biochemical interactions between signal and sensor that initiate the signaling cascade are often poorly understood. Here, we review the physical and chemical signals that Gram-negative enteric pathogens use to regulate T3SS expression during infection. We highlight the recent structural and functional studies that have elucidated the biochemical properties governing both the interaction between sensor and signal and the mechanisms of signal transduction from sensor to downstream transcriptional networks.

  19. Environmental factors regulating the recruitment of walleye Sander vitreus and white bass Morone chrysops in irrigation reservoirs

    Science.gov (United States)

    DeBoer, Jason A.; Pope, Kevin L.; Koupal, Keith D.

    2013-01-01

    Understanding the environmental factors that regulate fish recruitment is essential for effective management of fisheries. Generally, first-year survival, and therefore recruitment, is inherently less consistent in systems with high intra- and interannual variability. Irrigation reservoirs display sporadic patterns of annual drawdown, which can pose a substantial challenge to recruitment of fishes. We developed species-specific models using an 18-year data set compiled from state and federal agencies to investigate variables that regulate the recruitment of walleye Sander vitreus and white bass Morone chrysops in irrigation reservoirs in south-west Nebraska, USA. The candidate model set for walleye included only abiotic variables (water-level elevation, minimum daily air temperature during winter prior to hatching, annual precipitation, spring warming rate and May reservoir discharge), and the candidate model set for white bass included primarily biotic variables (catch per unit effort (CPUE) of black crappie Pomoxis nigromaculatus, CPUE of age-0 walleye, CPUE of bluegill Lepomis macrochirus and CPUE of age-3 and older white bass), each of which had a greater relative importance than the single abiotic variable (minimum daily air temperature during winter after hatching). Our findings improve the understanding of the recruitment of fishes in irrigation reservoirs and the relative roles of abiotic and biotic factors.

  20. Using Mechanistic Studies to Model Riparian Tree Establishment Under Environmental Flow Scenarios on Regulated Rivers

    Science.gov (United States)

    Stella, J. C.; Battles, J. J.; McBride, J. R.; Orr, B. K.

    2007-12-01

    In the Central Valley of California, pioneer cottonwood and willow species dominate the near-river forests. Historically, seedling recruitment for these disturbance-adapted species coincided with spring floods. Changes in flow timing and magnitude due to river regulation have decreased the success of seedling cohorts and contributed to the decline of these riparian tree populations. In order to address gaps in our understanding of these species and potential restoration strategies, we field-calibrated a conceptual model of seedling recruitment for the dominant pioneer woody species, Populus fremontii, Salix gooddingii, and S. exigua. We conducted experiments to identify seedling desiccation thresholds and seed longevity, used field studies to measure seedling competition and seasonal seed release patterns, and modeled interannual differences in dispersal timing using a degree-day model. These studies were integrated into a recruitment model that generates annual estimates of seedling density and bank elevation based on inputs of seasonal river discharge, seed dispersal timing, and seedling mortality from desiccation. The model predictions successfully captured interannual and species-level patterns in recruitment observed independently throughout a 20-km reach of the lower Tuolumne River from 2002-04. The model correctly predicted that seedling densities were highest in 2004 and lowest in 2003, and that S. exigua recruitment would be less extensive than for the two tree species. This work shows promise as both a quantitative approach linking hydrology, climate and plant community dynamics, and as a process-based framework for guiding flow releases and other management actions to restore riparian tree population along Central Valley rivers.

  1. The environmental regulation of maturation in goldfish, Carassius auratus: effects of various LED light spectra.

    Science.gov (United States)

    Shin, Hyun Suk; Habibi, Hamid R; Choi, Cheol Young

    2014-02-01

    While there have been a number of studies on the effects of photoperiod and duration of light and dark exposure, much less information is available on the importance of light intensity. This study investigated the effects of exposure of goldfish, Carassius auratus exposed to white fluorescent bulbs, and red (peak at 630nm), and green (530nm) light emitting diodes (LEDs) at approximately 0.9W/m(2) (12-h light:12-h dark) for four months on a number of hormones of the hypothalamus-pituitary-gonad (HPG) axis, in vivo and in vitro. We investigated the effects of native GnRH molecules (gonadotropin-releasing hormones; salmon GnRH, sGnRH; and chicken GnRH-II, cGnRH-II), gonadotropin hormones (GTHα; follicle-stimulating hormone, FSH-β; luteinizing hormone, LH-β2), kisspeptin 1 (Kiss1) and G protein-coupled receptor 54 (GPR54) mRNA levels. Furthermore, we measured LH and 17α-hydroxypregnenolone levels in plasma and we performed gonad histological observations. GnRHs, Kiss1, GPR54 and GTH mRNA and plasma LH and 17α-hydroxypregnenolone levels in the in vivo and in vitro groups exposed to green LEDs were significantly higher than the other groups. Histological analysis revealed the presence of oocytes in the yolk stage in fish exposed to green light. These results suggest that green wavelengths regulate the HPG axis and enhance sexual maturation in goldfish. Copyright © 2013 Elsevier Inc. All rights reserved.

  2. [Peculiarities of regulation of legal relations in the field of environmental and hygiene safety of the population in The Russian Federation at the present stage].

    Science.gov (United States)

    Karelin, A O; Eremin, G B; Lomtev, A Iu

    2012-01-01

    The results of the comparative legal analysis of the legislation of the Russian Federation in the field of environmental security have been presented, theoretical and legal basis for the subsequent development of recommendations for the development and harmonization of legislation in the field of providing environmental security and environmental protection has been defined. The formation of ecological civil law and conceptual questions of territory development guaranteeing ecological safety have been considered. Objects of the study were international treaties, Constitution of Russian Federation, Law on Environmental Protection, Land Code and other laws containing positions concerning ecological safety and environmental protection. Identified as a result of the present study the contradictions in the area of law allow to develop and submit proposals for the improvement of legal regulation in the field of environmental and hygienic safety.

  3. Why small and medium chemical companies continue to pose severe environmental risks in rural China.

    Science.gov (United States)

    He, Guizhen; Zhang, Lei; Mol, Arthur P J; Wang, Tieyu; Lu, Yonglong

    2014-02-01

    In China, rural chemical SMEs are often believed to still largely operate below the sustainability radar. This paper investigates to what extent and how chemical SMEs are already experiencing pressure to improve their environmental performance, using an in-depth case study in Jasmine County, Hebei province. The results show that local residents had rather low trust in the environmental improvement promises made by the enterprises and the local government, and disagreed with the proposed improvement plans. Although the power of local residents to influence decision making remained limited, the chemical SMEs started to feel increasing pressures to clean up their business, from governments, local communities and civil society, and international value chain stakeholders. Notwithstanding these mounting pressures chemical SME's environmental behavior and performance has not changed radically for the better. The strong economic ties between local county governments and chemical SMEs continue to be a major barrier for stringent environmental regulation. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. Effects of the lipid regulating drug clofibric acid on PPARα-regulated gene transcript levels in common carp (Cyprinus carpio) at pharmacological and environmental exposure levels

    Energy Technology Data Exchange (ETDEWEB)

    Corcoran, Jenna, E-mail: J.F.Corcoran@exeter.ac.uk [University of Exeter, Biosciences, College of Life & Environmental Sciences, Exeter EX4 4QD (United Kingdom); Winter, Matthew J., E-mail: M.Winter@exeter.ac.uk [AstraZeneca Global Environment, Brixham Laboratory, Freshwater Quarry, Brixham TQ5 8BA (United Kingdom); Lange, Anke, E-mail: A.Lange@exeter.ac.uk [University of Exeter, Biosciences, College of Life & Environmental Sciences, Exeter EX4 4QD (United Kingdom); Cumming, Rob, E-mail: Rob.Cumming@astrazeneca.com [AstraZeneca Global Environment, Brixham Laboratory, Freshwater Quarry, Brixham TQ5 8BA (United Kingdom); Owen, Stewart F., E-mail: Stewart.Owen@astrazeneca.com [AstraZeneca Global Environment, Brixham Laboratory, Freshwater Quarry, Brixham TQ5 8BA (United Kingdom); Tyler, Charles R., E-mail: C.R.Tyler@exeter.ac.uk [University of Exeter, Biosciences, College of Life & Environmental Sciences, Exeter EX4 4QD (United Kingdom)

    2015-04-15

    Highlights: • CFA appears to have a low propensity to bioconcentrate and has a plasma half-life of <4 days in carp. • CFA increases levels of mRNA of a number of genes known to be regulated by PPARα in mammals. • PPARα activation changes levels of mRNA of genes involved with several detoxification/ biotransformation system components in carp. • CFA alters levels of mRNA and activity of the inducible β-oxidation pathway enzyme Acox1, a known indicator of peroxisome proliferator exposure. - Abstract: In mammals, the peroxisome proliferator-activated receptor α (PPARα) plays a key role in regulating various genes involved in lipid metabolism, bile acid synthesis and cholesterol homeostasis, and is activated by a diverse group of compounds collectively termed peroxisome proliferators (PPs). Specific PPs have been detected in the aquatic environment; however little is known on their pharmacological activity in fish. We investigated the bioavailability and persistence of the human PPARα ligand clofibric acid (CFA) in carp, together with various relevant endpoints, at a concentration similar to therapeutic levels in humans (20 mg/L) and for an environmentally relevant concentration (4 μg/L). Exposure to pharmacologically-relevant concentrations of CFA resulted in increased transcript levels of a number of known PPARα target genes together with increased acyl-coA oxidase (Acox1) activity, supporting stimulation of lipid metabolism pathways in carp which are known to be similarly activated in mammals. Although Cu,Zn-superoxide dismutase (Sod1) activity was not affected, mRNA levels of several biotransformation genes were also increased, paralleling previous reports in mammals and indicating a potential role in hepatic detoxification for PPARα in carp. Importantly, transcription of some of these genes (and Acox1 activity) were affected at exposure concentrations comparable with those reported in effluent discharges. Collectively, these data suggest that CFA

  5. Federal Environmental and Occupational Toxicology Regulations and Reporting Requirements: a Practical Approach to What the Medical Toxicologist Needs to Know, Part 2

    OpenAIRE

    Schwartz, Michael D.; Dell’Aglio, Damon M.; Nickle, Richard; Hornsby-Myers, Jennifer

    2014-01-01

    Toxicologists are often called upon to assist in environmental, industrial, occupational and public health assessments. Accordingly, medical toxicologists may find it prudent to be aware of applicable federal toxicological regulations and reporting requirements and of the roles of relevant federal agencies. These regulations are numerous, complex, and have evolved and expanded over time, making it difficult for toxicologists to sustain a current knowledge base. This article reviews the pertin...

  6. Federal Environmental and Occupational Toxicology Regulations and Reporting Requirements: A Practical Approach to What the Medical Toxicologist Needs to Know, Part 1

    OpenAIRE

    Schwartz, Michael D.; Dell’Aglio, Damon M.; Nickle, Richard; Hornsby-Myers, Jennifer

    2014-01-01

    Toxicologists are often called upon to assist in environmental, industrial, occupational and public health assessments. Accordingly, medical toxicologists may find it prudent to be aware of applicable federal toxicological regulations and reporting requirements and of the roles of relevant federal agencies. These regulations are numerous, complex, and have evolved and expanded over time, making it difficult for toxicologists to sustain a current knowledge base. This article reviews the pertin...

  7. Issues of environmental compliance in developing countries.

    Science.gov (United States)

    Singh, S; Rajamani, S

    2003-01-01

    Environmental laws define the scarcity of environmental resources as they affect the factor endowment of a country and therefore its position in the international division of labour. There is now also a general agreement that applying the "polluter pays" principle should solve environmental problems. As the burden of abatement increases, as measured by the ratio of abatement expenditure to sales, there is definitely an incentive for firms to either invest in cleaner technology or more efficient abatement technology. There is also evidence that taxes and charges, designed to internalise externalities, can actually affect trade. It is interesting to know if the developing countries face particular market access problems in the face of stringent environmental standards and regulations. While it is true that stringent measures impose market access restrictions and cause limitations on competitiveness, this is much more widely felt by the developing countries because of lack of infrastructure and monitoring facilities, limited technology choices, inadequate access to environment-friendly raw materials, lack of complete information, presence of small-scale exporters and emergence of environmental standards in sectors of export interest to developing countries. The small and medium enterprises often divert sales either to the domestic market or to external markets where environmental requirements are less stringent, in order to save on their costs. In developing countries, 80% of the tanning industry is comprised of small and medium enterprises (SMEs) processing raw to semi-finished leather, usually less than 2 tons per day. In Europe and other developed countries the SMEs in the leather sector have vanished due to strict environmental legislation and this will likely occur in developing countries also. The environmental legislation has not always been practical, either because the laws are too ambitious or unrealistic in certain parameters, or because they have lacked

  8. Economic and environmental performance of future fusion plants in comparison

    International Nuclear Information System (INIS)

    Hamacher, T.; Saez, R.M.; Lako, P.

    2001-01-01

    If the good performance of fusion as technology with no CO 2 emission during normal operation and rather low external costs, reflecting the advantageous environmental and safety characteristics, are considered in future energy regulations, fusion can win considerable market shares in future electricity markets. The economic performance was elaborated for Western Europe for the time period till 2100. The software tool MARKAL widely used in energy research was used to simulate and optimise the development of the Western European energy system. Two different scenarios were considered, the main difference was the interest rate for investments. Stringent CO 2 -emission strategies lead to considerable market shares for fusion. As a comprehensive indicator of the environmental and safety performance of fusion plants the external costs following the ExternE method was used. External costs of fusion are rather low, much below the cost of electricity, and are in the same range as photovoltaics and wind energy. (author)

  9. Energy-economy relationship and environmental regulation in the presence of unrecorded economy; Relation energie-economie et regulation environnementale en presence de l'economie non-enregistree

    Energy Technology Data Exchange (ETDEWEB)

    Karanfil, F.

    2008-12-15

    This PhD thesis including five manuscripts and a brief international comparison analysis proposes a multi-field study on the economic and environmental effects of energy consumption. It first investigates the causal relationship between economic growth and energy consumption in Turkey and then offers a new methodology for the estimation of unrecorded economy based on environmental data. The thesis develops also asymmetric information models, where the regulator does not know the true emission level of each firm that it wishes to regulate, so as to examine to what extend different enforcement mechanisms affect incentives for the firms to reduce polluting emissions and to invest in clean energy technologies. In order to provide a complete insight on the effects of both fiscal and environmental enforcement policies, some similar analysis are conducted taking into account the existence of unrecorded economy. The results in this thesis essentially show that: first, energy conservation policies can be implemented in order to reduce greenhouse gas emissions without any adverse effect on the recorded economic activities; second, different audit mechanisms should be used depending on the environmental objective of the enforcement agency; third, in some cases, environmental regulations may increase the size of unrecorded economy; fourth, economic policies to combat unrecorded economy may not serve as a complement to energy conservation policies. (author)

  10. Incentives and regulation in banking

    NARCIS (Netherlands)

    Martynova, N.

    2015-01-01

    The financial crisis of 2007-2008 has unveiled the hidden flaws in the regulatory framework of the financial sector. The rules of the game established by regulators were not stringent enough and provided bankers with wrong incentives to gamble with depositors’ money. There are two major challenges

  11. New approach to the assessment and reduction of health risks and environmental impacts originating from TENORM according to EC regulation

    Energy Technology Data Exchange (ETDEWEB)

    Poffijn, A. [Laboratory for Nuclear Physics, Gent (Belgium); Kraus, W.D. [Bundesamt fur Strahlenschutz, Berlin (Germany)

    2001-07-01

    The New Basic Safety Standards as laid down in the Directive 96/29/Euratom differ from the earlier versions in that specific provisions have been formulated in Title VII for exposure to natural radiation sources. The scope of its application involves work activities, within which the presence of natural radiation sources may lead to exposures of workers and/or members of the public that cannot be ignored form the point of view of radiation protection. Two groups of work activities are of particular concern : the processing and/or storage of materials with enhanced concentrations of naturally occurring radionuclides and the production of residues causing a significant increase in the exposure of workers and members of the public. The Member States have to identity the activities of concern and they are given a high degree of flexibility in implementing the articles on natural radiation sources into national legislation. There is, however, a great need to harmonize the national approaches. Therefore guidance on the likely level of regulation of various materials and recommendations on the identification of such workplaces and on the nature of appropriate control have been prepared. The proposed set of screening and reference levels is intended as a first order approach, needing in some cases more detailed investigations. As a particular case, the detailed investigations done in relation to the phosphate industry and its environmental impact will be described and discussed. (authors)

  12. Analysis of celery (Apium graveolens) mannitol dehydrogenase (Mtd) promoter regulation in Arabidopsis suggests roles for MTD in key environmental and metabolic responses.

    Science.gov (United States)

    Zamski, E; Guo, W W; Yamamoto, Y T; Pharr, D M; Williamson, J D

    2001-11-01

    Of the growing list of promising genes for plant improvement, some of the most versatile appear to be those involved in sugar alcohol metabolism. Mannitol, one of the best characterized sugar alcohols, is a significant photosynthetic product in many higher plants. The roles of mannitol as both a metabolite and an osmoprotectant in celery (Apium graveolens) are well documented. However, there is growing evidence that 'metabolites' can also have key roles in other environmental and developmental responses in plants. For instance, in addition to its other properties, mannitol is an antioxidant and may have significant roles in plant-pathogen interactions. The mannitol catabolic enzyme mannitol dehydrogenase (MTD) is a prime modulator of mannitol accumulation in plants. Because the complex regulation of MTD is central to the balanced integration of mannitol metabolism in celery, its study is crucial in clarifying the physiological role(s) of mannitol metabolism in environmental and metabolic responses. In this study we used transformed Arabidopsis to analyze the multiple environmental and metabolic responses of the Mtd promoter. Our data show that all previously described changes in Mtd RNA accumulation in celery cells mirrored changes in Mtd transcription in Arabidopsis. These include up-regulation by salicylic acid, hexokinase-mediated sugar down-regulation, and down-regulation by salt, osmotic stress and ABA. In contrast, the massive up-regulation of Mtd expression in the vascular tissues of salt-stressed Arabidopsis roots suggests a possible role for MTD in mannitol translocation and unloading and its interrelation with sugar metabolism.

  13. Co-ordinate regulation of Salmonella typhimurium invasion genes by environmental and regulatory factors is mediated by control of hilA expression.

    Science.gov (United States)

    Bajaj, V; Lucas, R L; Hwang, C; Lee, C A

    1996-11-01

    During infection of their hosts, salmonellae enter intestinal epithelial cells. It has been proposed that when Salmonella typhimurium is present in the intestinal lumen, several environmental and regulatory conditions modulate the expression of invasion factors required for bacterial entry into host cells. We report here that the expression of six different S. typhimurium invasion genes encoded on SPI1 (Salmonella pathogenicity island 1) is co-ordinately regulated by oxygen, osmolarity, pH, PhoPQ, and HilA. HilA is a transcriptional activator of the OmpR/ToxR family that is also encoded on SPI1. We have found that HilA plays a central role in the co-ordinated regulation of invasion genes by environmental and regulatory conditions. HilA can activate the expression of two invasion gene-lacZY fusions on reporter plasmids in Escherichia coll, suggesting that HilA acts directly at invasion-gene promoters in S. typhimurium. We have found that the regulation of invasion genes by oxygen, osmolarity, pH, and PhoPQ is indirect and is mediated by regulation of hilA expression by these environmental and regulatory factors. We hypothesize that the complex and co-ordinate regulation of Invasion genes by HilA is an important feature of salmonella pathogenesis and allows salmonellae to enter intestinal epithelial cells.

  14. Austria's environmental law in comparison with the environmental law of the EC

    International Nuclear Information System (INIS)

    Jantscher, S.H.

    1991-11-01

    The thesis describes and compares the environmental legislation in Austria and the EC. A short introduction into structure and organization of EC-institutions and EC-legislation in followed by an examination of the constitutional foundations of environmental policy in Austria and the EC respectively. After the adoption for the Single European Act, the EEC-Treaty provides for objectives, orientation criteria and instruments regarding environmental protection. These provisions constitute a valid basis for environmental action. The adoption of a constitutional law does equally declare environmental protection as an objective of the state in Austria, however, its significance is regarded as rather controversial. Some provinces ('Laender') have shown a higher degree of sensitivity in their constitutions . The distribution of powers between the EC and its member stated in the field of environmental protection is of particular interests. It is shown, that the principle of subsidiarity and the safeguard-clauses leave discretion to the member states. Much will be determined by the European Court of Justice (ECJ) . Main emphasis has been placed on the description and comparison of Austria's and the EEC-environmental legislation. Environmental legislation of Austria as well as the EC is outlined sector by sector (i.e. water, air, chemicals, waste, soil, fauna and flora) and subsequently the object of a detailed comparison. Criteria, such as - preventiveness -stringency - focus, depth and comprehensiveness - clearness and legal force of the regulations have been applied. For most of the mentioned sectors it is correct to state, that Austria's legislation is more preventive, advanced, comprehensive and stringent (especially regulations related to water, waste, chemicals, also air) . However, there are particular areas (e.g. air quality objectives, noise limits for construction plants) where Austria' s legislation may well get a fresh impetus

  15. Electron accelerators for environmental protection

    International Nuclear Information System (INIS)

    Zimek, Z.

    1998-01-01

    The primary objective of this publication is to provide information suitable for electron accelerators implementation in facilities applying radiation technology for environmental protection. It should be noticed that radiation processing has been successfully used in the fields of crosslinking polymer curing and medical products sterilization for more than 40 years. Practical application of radiation technology today extends on SO 2 and NO x removal from the flue gas (one of major power intensive radiation processing), destruction and removal of organic chemicals from water, decreasing bacteria content in the irradiated sludge and waste water. On the other hand the increased awareness of environmental pollution hazards and more stringent waste regulations in many countries may open stronger support for environmentally oriented technologies. This publication provides an evaluation of electron accelerators capabilities in respect of environmental applications where technological and economical criteria are now well defined. In order to determine the potential of electron accelerators, the literature data were examined as well visits and meetings with various accelerator manufacturers were performed by the author. Experience of the author in accelerator facilities construction and exploitation including those which were used for environmental protection are significant part of this publication. The principle of accelerator action was described in Chapter 1. Early development, accelerator classification and fields of accelerators application were included to this chapter as well. Details of accelerator construction was described in Chapter 2 to illustrate physical capability of accelerators to perform the function of ionizing radiation source. Electron beam extraction devices, under beam equipment, electron beam parameters and measuring methods were characterized in this chapter as well. Present studies of accelerator technology was described in Chapter 3, where

  16. A review of the methods used by the US Environmental Protection Agency to assess the financial impacts of the repository regulations

    Energy Technology Data Exchange (ETDEWEB)

    Pflum, C.G.; Mattson, S.R.; Matthusen, A.C.

    1994-02-16

    All Federal agencies must consider the financial impacts of their regulations. When costs significantly outweigh benefits, the Office of Management and Budget can recommend that Congress not provide the funds needed to implement the regulation. Without funds, the agency is forced to either revise or retract the regulation. This has happened previously with a regulation on uranium mill tailings proposed by the US Nuclear Regulatory Commission (NRC) and it could happen again with the US Environmental Protection Agency (EPA) regulations that govern the disposal of high-level radioactive waste (HLW). The EPA (1985, 1992) claims that its regulation: ``Environmental Standards for the Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Waste`` (40 CFR Part 191 or standards) does not increase costs above what the US Department of Energy (DOE) would spend anyway or, at most, what the DOE would spend to comply with 10 CFR Part 60: a regulation promulgated by the NRC. This report reviews and disputes the EPA claim. In Chapter 2 a summary of the basis for the EPA claim is presented and in Chapter 3 a critique of the basis of the claim is presented. This critique finds the EPA basis unrealistic, incomplete, and misleading. According to the EPA, a repository at Yucca Mountain would easily meet 40 CFR Part 191 even without the use of special engineered barriers. Because the NRC regulation (10 CFR Part 60) requires engineered barriers, the EPA places the onus for regulatory costs on the NRC. We disagree; the EPA standards drive regulatory costs as much as NRC regulations. The EPA has the higher responsibility for setting the overall standard for safety while the NRC can only implement this standard.

  17. A review of the methods used by the US Environmental Protection Agency to assess the financial impacts of the repository regulations

    International Nuclear Information System (INIS)

    Pflum, C.G.; Mattson, S.R.; Matthusen, A.C.

    1994-01-01

    All Federal agencies must consider the financial impacts of their regulations. When costs significantly outweigh benefits, the Office of Management and Budget can recommend that Congress not provide the funds needed to implement the regulation. Without funds, the agency is forced to either revise or retract the regulation. This has happened previously with a regulation on uranium mill tailings proposed by the US Nuclear Regulatory Commission (NRC) and it could happen again with the US Environmental Protection Agency (EPA) regulations that govern the disposal of high-level radioactive waste (HLW). The EPA (1985, 1992) claims that its regulation: ''Environmental Standards for the Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Waste'' (40 CFR Part 191 or standards) does not increase costs above what the US Department of Energy (DOE) would spend anyway or, at most, what the DOE would spend to comply with 10 CFR Part 60: a regulation promulgated by the NRC. This report reviews and disputes the EPA claim. In Chapter 2 a summary of the basis for the EPA claim is presented and in Chapter 3 a critique of the basis of the claim is presented. This critique finds the EPA basis unrealistic, incomplete, and misleading. According to the EPA, a repository at Yucca Mountain would easily meet 40 CFR Part 191 even without the use of special engineered barriers. Because the NRC regulation (10 CFR Part 60) requires engineered barriers, the EPA places the onus for regulatory costs on the NRC. We disagree; the EPA standards drive regulatory costs as much as NRC regulations. The EPA has the higher responsibility for setting the overall standard for safety while the NRC can only implement this standard

  18. Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice

    Directory of Open Access Journals (Sweden)

    Allison R. Rogala

    2018-02-01

    Full Text Available Crohn's disease (CD represents a chronic inflammatory disorder of the intestinal tract. Several susceptibility genes have been linked to CD, though their precise role in the pathogenesis of this disorder remains unclear. Immunity-related GTPase M (IRGM is an established risk allele in CD. We have shown previously that conventionally raised (CV mice lacking the IRGM ortholog, Irgm1 exhibit abnormal Paneth cells (PCs and increased susceptibility to intestinal injury. In the present study, we sought to utilize this model system to determine if environmental conditions impact these phenotypes, as is thought to be the case in human CD. To accomplish this, wild-type and Irgm1−/− mice were rederived into specific pathogen-free (SPF and germ-free (GF conditions. We next assessed how these differential housing environments influenced intestinal injury patterns, and epithelial cell morphology and function in wild-type and Irgm1−/− mice. Remarkably, in contrast to CV mice, SPF Irgm1−/− mice showed only a slight increase in susceptibility to dextran sodium sulfate-induced inflammation. SPF Irgm1−/− mice also displayed minimal abnormalities in PC number and morphology, and in antimicrobial peptide expression. Goblet cell numbers and epithelial proliferation were also unaffected by Irgm1 in SPF conditions. No microbial differences were observed between wild-type and Irgm1−/− mice, but gut bacterial communities differed profoundly between CV and SPF mice. Specifically, Helicobacter sequences were significantly increased in CV mice; however, inoculating SPF Irgm1−/− mice with Helicobacter hepaticus was not sufficient to transmit a pro-inflammatory phenotype. In summary, our findings suggest the impact of Irgm1-deficiency on susceptibility to intestinal inflammation and epithelial function is critically dependent on environmental influences. This work establishes the importance of Irgm1−/− mice as a model to elucidate host

  19. pOp6/LhGR: a stringently regulated and highly responsive dexamethasone-inducible gene expression system for tobacco

    Czech Academy of Sciences Publication Activity Database

    Šámalová, Markéta; Brzobohatý, Břetislav; Moore, Ian

    2005-01-01

    Roč. 41, - (2005), s. 919-935 ISSN 0960-7412 R&D Projects: GA AV ČR(CZ) IAA5004001; GA AV ČR(CZ) KSK5052113 Institutional research plan: CEZ:AV0Z50040507 Keywords : chemically inducible gene expression * cytokinin-biosynthetic gene ipt * tobacco Subject RIV: BO - Biophysics Impact factor: 6.969, year: 2005

  20. Impact of a More Stringent Blood Lead Level Recommendation for Children (Ages 1-5): Vulnerabilities Related to Housing, Food Security, Vitamins, and Environmental Toxicants

    Science.gov (United States)

    The adverse health effects of lead (Pb) exposure in young children are well known. Non-Hispanic black children historically have higher blood Pb levels (BLL) compared to Mexican-Americans and non- Hispanic white children (CDC-MMWR). In the past, BLL tests below 10 µg/dL m...

  1. Regulating chemical accumulation in the environment: the integration of toxicology and economics in environmental policy-making

    National Research Council Canada - National Science Library

    Swanson, Timothy M; Vighi, M

    1998-01-01

    ... particular region (the European Union), the book forms a general study of the value of interdisciplinary approaches in environmental policy-making. This volume will be a valuable resource for a broad group of academics and researchers in the area of environmental science and environmental policy. It will also form a useful supplementary reference tex...

  2. Transcriptional regulation of receptor-like protein genes by environmental stresses and hormones and their overexpression activities in Arabidopsis thaliana.

    Science.gov (United States)

    Wu, Jinbin; Liu, Zhijun; Zhang, Zhao; Lv, Yanting; Yang, Nan; Zhang, Guohua; Wu, Menyao; Lv, Shuo; Pan, Lixia; Joosten, Matthieu H A J; Wang, Guodong

    2016-05-01

    Receptor-like proteins (RLPs) have been implicated in multiple biological processes, including plant development and immunity to microbial infection. Fifty-seven AtRLP genes have been identified in Arabidopsis, whereas only a few have been functionally characterized. This is due to the lack of suitable physiological screening conditions and the high degree of functional redundancy among AtRLP genes. To overcome the functional redundancy and further understand the role of AtRLP genes, we studied the evolution of AtRLP genes and compiled a comprehensive profile of the transcriptional regulation of AtRLP genes upon exposure to a range of environmental stresses and different hormones. These results indicate that the majority of AtRLP genes are differentially expressed under various conditions that were tested, an observation that will help to select certain AtRLP genes involved in a specific biological process for further experimental studies to eventually dissect their function. A large number of AtRLP genes were found to respond to more than one treatment, suggesting that one single AtRLP gene may be involved in multiple physiological processes. In addition, we performed a genome-wide cloning of the AtRLP genes, and generated and characterized transgenic Arabidopsis plants overexpressing the individual AtRLP genes, presenting new insight into the roles of AtRLP genes, as exemplified by AtRLP3, AtRLP11 and AtRLP28 Our study provides an overview of biological processes in which AtRLP genes may be involved, and presents valuable resources for future investigations into the function of these genes. © The Author 2016. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  3. Environmental variables regulating soil carbon dioxide efflux following clear-cutting of a Pinus radiata D. Don plantation

    Science.gov (United States)

    Arneth, A.; Kelliher, F. M.; Gower, S. T.; Scott, N. A.; Byers, J. N.; McSeveny, T. M.

    1998-03-01

    The regulation of soil surface CO2 efflux (Fs) from a dryland Pinus radiata clear-cut in New Zealand (658-mm annual rainfall, 50-mm soil water storage over 0.5-m depth of soil) was quantified using a multiplicative, soil moisture and temperature constraint model. Model parameters were determined from measurements of Fs by eddy covariance and by two portable CO2 analyzers equipped with soil chambers during 8 consecutive days in November 1995. Fs from the two chamber systems agreed consistently, but agreement between chamber and eddy covariance measurements was confined to a very small flux-range (1.5-2.5 μmol m-2 s-1). When the soil surface was wet and wind speed (u, a surrogate for static pressure fluctuations) was high, eddy covariance fluxes were >3 μmol m-2 s-1 (maximum 5.0 m-2 s-1), significantly higher than the chamber values. Including u as a third constraint in the model facilitated good predictions of Fs over the entire range of environmental conditions. Daily Fs during the study period ranged from 0.8 to 2.9 g C m-2. Driven by weather data from the forest fire station and subroutines for soil water balance and temperature, modeled Fs for the year ending in June 1996 was 0.37 kg C m-2. This year had below average (547 mm) rainfall. For a year with 640-mm rainfall, a significant increase of annual Fs (0.44 kg C m-2) demonstrated the severe restriction of soil microbial activity by moisture deficit at dryland sites. Moreover, when the soil was adequately watered, Fs was frequently restricted by low wind speed.

  4. A comparison of different regulatory approaches, analysis of the relative benefits of command and control, reflexive law and social licensing in ensuring oil industry compliance with environmentally sustainable practices and obligations

    Science.gov (United States)

    Ghanaati, Sahar

    This paper explores the relative benefits of command and control, reflexive law and social licensing in ensuring oil industry compliance with environmentally sustainable practices and obligations. Recognizing why oil sands and their development are significant, the background and development are reviewed first, and then the focus is shifted to look at its economics including the benefits, uncertainties and environmental costs of development. This paper examines how lawmakers in Canada have failed to meet their respective obligation. Drawing on environmental provisions, case law and legal scholars’ articles, books and reports, this paper examines the very problematic issue of oil sands regulation. It proposes to provide an in depth analysis of each regulatory forms and their application to the oil sands. It concludes that in order to solve the oil sands regulation challenges, a collaborative stringent enforcement of regulation from both federal and provincial governments, oil industry and public Pressure is required.

  5. Understanding environmental drivers in the regulation of soil respiration dynamics after fire in semi-arid ecosystems

    Science.gov (United States)

    Muñoz-Rojas, Miriam; Lewandrowski, Wolfgang; Erickson, Todd E.; Dixon, Kingsley W.; Merritt, David J.

    2016-04-01

    Keywords: Pilbara, soil CO2 efflux, soil C, soil moisture, soil temperature Introduction Soil respiration (Rs) has become a major research focus given the increase in atmospheric CO2 emissions and the large contribution of these CO2 fluxes from soils (Van Groenigen et al., 2014). In addition to its importance in the global C cycle, Rs is a fundamental indicator of soil health and quality that reflects the level of microbial activity and provides an indication of the ability of soils to support plant growth (Oyonarte et al., 2012; Munoz-Rojas et al., 2015). Wildfires can have a significant impact on Rs rates, with the scale of the impact depending on environmental factors such as temperature and moisture, and organic C content in the soil. Vegetation cover can have a significant effect on regulating organic C contents; and while advances are made into understanding the effects of fire on organic C contents and CO2 fluxes (Granged et al., 2011; Willaarts et al., 2015; Muñoz-Rojas et al., 2016), there is limited knowledge of the variability of Rs across ecosystem types, vegetation communities, and responses to fire. In this research we aimed to assess the impacts of a wildfire on the soil CO2 fluxes and soil respiration in a semi-arid ecosystem of Western Australia (Pilbara biogeographical region), and to understand the main environmental drivers controlling these fluxes in different vegetation types. The study has application for other arid and semi-arid regions of the world. Methods The study area was selected following a wildfire that affected 25 ha in February 2014. Twelve plots were established in the burnt site (B) within a 400 m2 area, and 12 plots in an adjacent unburnt control site. At each site, three plots were installed below the canopy of each of the most representative vegetation types of the areas: Eucalyptus trees, Acacia shrubs and Triodia grasses, and three on bare soil. Soil sampling and measurement of soil CO2 efflux, temperature and moisture were

  6. Analysis of the environmental control technology for oil shale development

    Energy Technology Data Exchange (ETDEWEB)

    de Nevers, N.; Eckhoff, D.; Swanson, S.; Glenne, B.; Wagner, F.

    1978-02-01

    The environmental control technology proposed in the various oil shale projects which are under development are examined. The technologies for control of air pollution, water pollution, and for the disposal, stabilization, and vegetation of the processed shale were thoroughly investigated. Although some difficulties may be encountered in any of these undertakings, it seems clear that the air and water pollution problems can be solved to meet any applicable standard. There are no published national standards against which to judge the stabilization and vegetation of the processed shale. However, based on the goal of producing an environmentally and aesthetically acceptable finished processed shale pile, it seems probable that this can be accomplished. It is concluded that the environmental control technology is available to meet all current legal requirements. This was not the case before Colorado changed their applicable Air Pollution regulations in August of 1977; the previous ones for the oil shale region were sufficiently stringent to have caused a problem for the current stage of oil shale development. Similarly, the federal air-quality, non-deterioration regulations could be interpreted in the future in ways which would be difficult for the oil shale industry to comply with. The Utah water-quality, non-deterioration regulations could also be a problem. Thus, the only specific regulations which may be a problem are the non-deterioration parts of air and water quality regulations. The unresolved areas of environmental concern with oil shale processing are mostly for the problems not covered by existing environmental law, e.g., trace metals, polynuclear organics, ground water-quality changes, etc. These may be problems, but no evidence is yet available that these problems will prevent the successful commercialization of oil shale production.

  7. The decision on the application to carry out a decommissioning project at Hinkley Point A Power Station under the Nuclear Reactors (Environmental Impact Assessment for Decommissioning) Regulations 1999

    International Nuclear Information System (INIS)

    2003-01-01

    European Council Directive 85/337/EEC, as amended by Council Directive 97/1 I/EC, sets out a framework on the assessment of the effects of certain public and private projects on the environment. The Directive is implemented in Great Britain for decommissioning nuclear reactor projects by the Nuclear Reactors (Environmental Impact Assessment for Decommissioning) Regulations 1999. The intention of the Directive and Regulations is to involve the public through consultation in considering the potential environmental impacts of a decommissioning project, and to make the decision-making process on granting consent open and transparent. The Regulations require the licensee to undertake an environmental impact assessment, prepare an environmental statement that summarises the environmental effects of the project, and apply to the Health and Safety Executive (HSE) for consent to carry out a decommissioning project. There is an optional stage where the licensee may request from HSE an opinion on what the environmental statement should contain (called a pre-application opinion). The licensee of Hinkley Point A Power Station, Magnox Electric pie, requested a pre-application opinion and provided information in a scoping report in December 2000. HSE undertook a public consultation on the scoping report and provided its pre- application opinion in April 2001. The licensee applied to HSE for consent to carry out a decommissioning project and provided an environmental statement in December 2001. Following a public consultation on the environmental statement, HSE requested further information that was subsequently provided by the licensee. A further public consultation was undertaken on the further information that ended in March 2003. All these public consultations involved around 60 organisations. HSE granted consent to carry out a decommissioning project at Hinkley Point A Power Station under the Regulations in July 2003, and attached conditions to the Consent. HSE took relevant

  8. Nevada Nuclear Waste Storage Investigations: A review of requirements for biological information in federal, state, and local environmental laws and regulations

    International Nuclear Information System (INIS)

    Collins, E.; O'Farrell, T.P.

    1987-01-01

    Biological information concerning Yucca Mountain collected since 1980 is evaluated to determine if it is sufficient to satisfy the requirements of the various federal, state, and local laws and regulations that pertain to environmental protection or to development of waste repositories. The pertinent requirements of each law are summarized, missing information is identified, and recommendations are made for studies to fill these gaps. 11 refs., 2 figs., 1 tab

  9. Can individual cognitions, self-regulation and environmental variables explain educational differences in vegetable consumption?: a cross-sectional study among Dutch adults

    OpenAIRE

    Springvloet, Linda; Lechner, Lilian; Oenema, Anke

    2014-01-01

    Background Educational differences in health-related behaviors, where low- and moderate-educated individuals have poorer outcomes than high-educated individuals, are persistent. The reasons for these differences remain poorly understood. This study explored whether individual cognitions, self-regulation and environmental-level factors may explain educational differences in vegetable consumption. Methods A cross-sectional study was conducted among 1,342 Dutch adults, of whom 54.5% were low/mod...

  10. The law concerning the environmental impact assessment. Vol. 1. Collection of regulations with an introduction to EIA law

    International Nuclear Information System (INIS)

    Peters, H.J.

    1995-01-01

    The present book contains all regulations relevant to EIA in compact form: The EU EIA Directive; the Federal Law on the EIA; the Procedural Rules of Atomic Energy Law; the Ninth Ordinance on the Federal Emissions Control Law including the pertinent general administrative regulation; the Federal Mining Law; the Federal Building Law; the Federal Regional Planning Law; and the EIA laws of the Laender such as implementing regulations, the Land EIA Laws, and the Land Planning Laws. There is a basic introduction to EIA law preceding this collection of regulations and laws. (orig./HP) [de

  11. Public choice and environmental regulation: tradable permit systems in the United States and CO2 taxation in Europe. New Horizons in Environmental Economics series

    DEFF Research Database (Denmark)

    Svendsen, Gert Tinggaard

    Svendsen provides a comprehensive description and assessment of the actual experience with systems of tradable permits for environmental management. Moreover, he puts this treatment in a public-choice framework so that we can understand why policy makers in Europe have chosen green taxes, while t...... their counterparts in the United States have opted for systems of tradable permits. The book is a valuable source for a basic understanding of the theory, the and the political economy of incentive-based policy instruments....

  12. Impact of new environmental and safety regulations on uranium exploration, mining, milling and management of its waste. Proceedings of a technical committee meeting

    International Nuclear Information System (INIS)

    2001-09-01

    Concern for health, safety and the environment has grown rapidly during the last two decades. Exploitation of any mineral commodity, including uranium, involves the modification of the surrounding environment. Appropriate regulations governing such activities can assure good practices and minimize possible negative impacts on the environment and the health and safety of the workers and the general public. During the past few years, a number of countries have promulgated new regulations related to uranium exploitation, mining, milling and the related waste management. Recent regulations are stricter in terms of environmental assessment, mitigation, radiation protection and control of waste. The impact of those regulations in developed countries has resulted in better planning of operations, improvement in mine and mill designs and a more efficient approach to tailings management. The Meeting was attended by 25 participants from 17 countries representing government organizations and private industry. This document includes 21 papers presented at the Meeting on new experiences in major uranium producing countries on the subject, past producers, as well as on country where regulations and related regulatory structure are still at the early evolutionary stage. Each of the papers was indexed separately

  13. New Features on the Environmental Regulation of Metabolism Revealed by Modeling the Cellular Proteomic Adaptations Induced by Light, Carbon, and Inorganic Nitrogen in Chlamydomonas reinhardtii.

    Science.gov (United States)

    Gérin, Stéphanie; Leprince, Pierre; Sluse, Francis E; Franck, Fabrice; Mathy, Grégory

    2016-01-01

    Microalgae are currently emerging to be very promising organisms for the production of biofuels and high-added value compounds. Understanding the influence of environmental alterations on their metabolism is a crucial issue. Light, carbon and nitrogen availability have been reported to induce important metabolic adaptations. So far, the influence of these variables has essentially been studied while varying only one or two environmental factors at the same time. The goal of the present work was to model the cellular proteomic adaptations of the green microalga Chlamydomonas reinhardtii upon the simultaneous changes of light intensity, carbon concentrations (CO2 and acetate), and inorganic nitrogen concentrations (nitrate and ammonium) in the culture medium. Statistical design of experiments (DOE) enabled to define 32 culture conditions to be tested experimentally. Relative protein abundance was quantified by two dimensional differential in-gel electrophoresis (2D-DIGE). Additional assays for respiration, photosynthesis, and lipid and pigment concentrations were also carried out. A hierarchical clustering survey enabled to partition biological variables (proteins + assays) into eight co-regulated clusters. In most cases, the biological variables partitioned in the same cluster had already been reported to participate to common biological functions (acetate assimilation, bioenergetic processes, light harvesting, Calvin cycle, and protein metabolism). The environmental regulation within each cluster was further characterized by a series of multivariate methods including principal component analysis and multiple linear regressions. This metadata analysis enabled to highlight the existence of a clear regulatory pattern for every cluster and to mathematically simulate the effects of light, carbon, and nitrogen. The influence of these environmental variables on cellular metabolism is described in details and thoroughly discussed. This work provides an overview of the

  14. Can individual cognitions, self-regulation and environmental variables explain educational differences in vegetable consumption?: a cross-sectional study among Dutch adults.

    Science.gov (United States)

    Springvloet, Linda; Lechner, Lilian; Oenema, Anke

    2014-12-06

    Educational differences in health-related behaviors, where low- and moderate-educated individuals have poorer outcomes than high-educated individuals, are persistent. The reasons for these differences remain poorly understood. This study explored whether individual cognitions, self-regulation and environmental-level factors may explain educational differences in vegetable consumption. A cross-sectional study was conducted among 1,342 Dutch adults, of whom 54.5% were low/moderate-educated. Individuals completed an online questionnaire, assessing education, vegetable consumption, demographics, individual cognitions (attitude towards consuming 200 grams of vegetables a day, self-efficacy, subjective norm, intention, perception of vegetables as being expensive), self-regulation (general self-regulation, vegetable-specific action- and coping planning) and environmental-level factors (perception of availability of vegetables in the supermarket and availability of vegetables at home). The joint-significance test was used to determine significant mediation effects. Low/moderate-educated individuals consumed less vegetables (M = 151.2) than high-educated individuals (M = 168.1, β = -0.15, P education and vegetable consumption (percentage mediated effect: 24.46%). Since attitude and availability of vegetables at home partially explain the difference in vegetable consumption between low/moderate- and high-educated individuals, these variables may be good target points for interventions to promote vegetable consumption among low/moderate-educated individuals.

  15. Achieving stringent climate targets. An analysis of the role of transport and variable renewable energies using energy-economy-climate models

    Energy Technology Data Exchange (ETDEWEB)

    Pietzcker, Robert Carl

    2014-07-01

    Anthropogenic climate change is threatening the welfare of mankind. Accordingly, policy makers have repeatedly stated the goal of slowing climate change and limiting the increase of global mean temperature to less than 2 C above pre-industrial times (the so-called ''two degree target''). Stabilizing the temperature requires drastic reductions of greenhouse gas (GHG) emissions to nearly zero. As the global system of energy supply currently relies on fossil fuels, reducing GHG emissions can only be achieved through a full-scale transformation of the energy system. This thesis investigates the economic requirements and implications of different scenarios that achieve stringent climate mitigation targets. It starts with the analysis of characteristic decarbonization patterns and identifies two particularly relevant aspects of mitigation scenarios: deployment of variable renewable energies (VRE) and decarbonization of the transport sector. After investigating these fields in detail, we turned towards one of the most relevant questions for policy makers and analyzed the trade-off between the stringency of a climate target and its economic requirements and implications. All analyses are based on the improvement, application, comparison, and discussion of large-scale IAMs. The novel ''mitigation share'' metric allowed us to identify the relevance of specific technology groups for mitigation and to improve our understanding of the decarbonization patterns of different energy subsectors. It turned out that the power sector is decarbonized first and reaches lowest emissions, while the transport sector is slowest to decarbonize. For the power sector, non-biomass renewable energies contribute most to emission reductions, while the transport sector strongly relies on liquid fuels and therefore requires biomass in combination with carbon capture and sequestration (CCS) to reduce emissions. An in-depth investigation of the solar power

  16. REVIEW OF THE METHODS USED IN STRATEGIC ENVIRONMENTAL ASSESSMENT OF PROJECTS OF REGULATIONS ON DETERMINING THE USE OF WATER CONDITIONS IN WATER REGIONS

    Directory of Open Access Journals (Sweden)

    Krzysztof Pyszny

    2014-10-01

    The aim of this study was to determine what methods of assessment are used for the strategic environmental assessment, and what is the range of usage of Geographic Information Systems (GIS in strategic environmental assessment of projects of regulations on determining the conditions for use of water in water regions in Poland. Based on the analysis it can be concluded that in most of the analyzed documents, the assessment criteria are not explicitly defined and not applying quantitative methods of forecasting the impact on the environment makes it impossible to compare the nature and primarily the scale of the impact on the individual components of the environment.Wider use of Geographic Information Systems in strategic environmental assessment is recommended, not only for data visualization but mainly for the use of tools helping to conduct spatial analysis and decision making. The results confirm that methods currently used in strategic environmental assessment are not sufficiently rewarding and provide technical and methodological challenge for experts working on their development. Solving the problem requires the development of more innovative and effective methods of evaluation.

  17. Management, regulation and environmental impacts of nitrogen fertilization in northwestern Europe under the Nitrates Directive; a benchmark study

    NARCIS (Netherlands)

    Grinsven, van H.J.M.; Berge, ten H.F.M.; Dalgaard, T.; Fraters, B.; Durand, P.; Hart, A.; Hofman, G.; Jacobsen, B.H.; Lalor, S.T.J.; Lesschen, J.P.; Osterburg, B.; Richards, K.G.; Techen, A.K.; Vertes, F.; Webb, J.; Willems, W.J.

    2012-01-01

    Implementation of the Nitrates Directive (NiD) and its environmental impacts were compared for member states in the northwest of the European Union (Ireland, United Kingdom, Denmark, the Netherlands, Belgium, Northern France and Germany). The main sources of data were national reports for the third

  18. Environmental sensor networks and continuous data quality assurance to manage salinity within a highly regulated river basin

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, N.W.T.; Ortega, R.; Holm, L.

    2010-01-05

    This paper describes a new approach to environmental decision support for salinity management in the San Joaquin Basin of California that focuses on web-based data sharing using YSI Econet technology and continuous data quality management using a novel software tool, Aquarius.

  19. Regional impacts of environmental regulations and technical change in the US forestry sector: a multiregional CGE analysis

    Science.gov (United States)

    Gouranga G. Das; Janki R.R. Alavalapati; Douglas R. Carter; Marions E. Tsigas

    2005-01-01

    In this paper, a multiregional computable general equilibrium model, which divides the United States (US) into four broad geographical regions and aggregates other nations into the rest of the world, is used to analyze the effects associated with environmental and technological policy shifts in the US forest sector. In particular, we analyze the impacts of: (i) a 20%...

  20. Historic and future trends of vehicle emissions in Beijing, 1998-2020: A policy assessment for the most stringent vehicle emission control program in China

    Science.gov (United States)

    Zhang, Shaojun; Wu, Ye; Wu, Xiaomeng; Li, Mengliang; Ge, Yunshan; Liang, Bin; Xu, Yueyun; Zhou, Yu; Liu, Huan; Fu, Lixin; Hao, Jiming

    2014-06-01

    As a pioneer in controlling vehicle emissions within China, Beijing released the Clean Air Action Plan 2013-2017 document in August 2013 to improve its urban air quality. It has put forward this plan containing the most stringent emission control policies and strategies to be adopted for on-road vehicles of Beijing. This paper estimates the historic and future trends and uncertainties in vehicle emissions of Beijing from 1998 to 2020 by applying a new emission factor model for the Beijing vehicle fleet (EMBEV). Our updated results show that total emissions of CO, THC, NOx and PM2.5 from the Beijing vehicle fleet are 507 (395-819) kt, 59.1 (41.2-90.5) kt, 74.7 (54.9-103.9) kt and 2.69 (1.91-4.17) kt, respectively, at a 95% confidence level. This represents significant reductions of 58%, 59%, 31% and 62%, respectively, relative to the total vehicle emissions in 1998. The past trends clearly posed a challenge to NOx emission mitigation for the Beijing vehicle fleet, especially in light of those increasing NOx emissions from heavy-duty diesel vehicles (HDDVs) which have partly offset the reduction benefit from light-duty gasoline vehicles (LDGVs). Because of recently announced vehicle emission controls to be adopted in Beijing, including tighter emissions standards, limitations on vehicle growth by more stringent license control, promotion of alternative fuel technologies (e.g., natural gas) and the scrappage of older vehicles, estimated vehicle emissions in Beijing will continue to be mitigated by 74% of CO, 68% of THC, 56% of NOx and 72% of PM2.5 in 2020 compared to 2010 levels. Considering that many of the megacities in China are facing tremendous pressures to mitigate emissions from on-road vehicles, our assessment will provide a timely case study of significance for policy-makers in China.

  1. Impact of environmental pollutants on the endocrine regulation of reproduction. Experimental report. Final report; Auswirkungen von Umweltschadstoffen auf die endokrine Regulation der Fortpflanzung. T. A. Sachlicher Bericht. Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1992-12-31

    The investigation had the aim to establish the impact of environmentally relevant biocides on different aspects of reproduction. The human granulosa lutein cells used stemmed from patients of an in-vitro fertilization programme. In 29 to 71 per cent of cases, in-vitro exposure of granulosa cells to the biocides PCB, DDT, DDD, DDE, HCB and HCE resulted in reduced progesterone secretions. The impact of biocide exposure on in-vitro secretion of estradiol was less unequivocal. Parallel testing of progesterone and estradiol secretion in the same cell populations showed that biocides do not affect the two steroids in the same degree. The conclusion to be drawn from the results is that steroid, and especially progesterone, production in women who are exposed to lipophilic biocides is impaired. (UG) [Deutsch] Das Ziel der Untersuchung war, inwieweit umweltrelevante Biozide fuer verschiedene Aspekte der Fortpflanzung von Bedeutung sind. Die untersuchten menschlichen Granulosa-Luteinzellen stammten von Patientinnen eines in vitro-Fertilisationsprogrammes. Die in vitro-Exposition von Granulosa-Zellen mit den Bioziden PCB, DDT, DDD, DDE, HCB und HCE fuehrten in 29%-71% zu verringerten Progesteron-Sekretionen. Die Auswirkungen der Biozidbelastung auf die in vitro-Estradiol-Sektretion war weniger eindeutig. Parallele Testung von Progesteron- und Estradiol-Sekretion an den gleichen Zellpopulationen zeigten, dass die Biozidwirkungen auf die beiden Steroide nicht gleichmaessig gerichtet waren. Aufgrund der Ergebnisse muss eine Beeintraechtigung der Steroid-, insbesondere der Progesteron-Produktion, bei der Frau durch Belastung mit lipophilen Bioziden angenommen werden. (UG)

  2. New environmental policy instruments to realize forest expansion in Flanders (northern Belgium): A base for smart regulation?

    NARCIS (Netherlands)

    Gossum, Van P.; Ledene, L.; Arts, B.J.M.; Vreese, De R.; Langenhove, Van G.; Verheyen, K.

    2009-01-01

    This paper evaluates the current instrument mix, designs options for smart regulation and estimates the support base of new instruments for the forest expansion policy in Flanders (northern Belgium). The framework applied is a combination of theories on instrument choice (ICT), policy transfer and

  3. Voluntary Environmental Governance Arrangements

    NARCIS (Netherlands)

    van der Heijden, J.

    2012-01-01

    Voluntary environmental governance arrangements have focal attention in studies on environmental policy, regulation and governance. The four major debates in the contemporary literature on voluntary environmental governance arrangements are studied. The literature falls short of sufficiently

  4. The influence of environmental factors on heart rate chronostructure depending on the individual characteristics of autonomic regulation. Results of long-term medical-ecological studies.

    Science.gov (United States)

    Isaeva, Olga; Zenchenko, Tatiana; Breus, Tamara; Chernikova, Anna; Baevsky, Roman

    It was previously shown [Baevsky, Petrov, 1998] that during space flight under influence of geomagnetic disturbances there are both specific response of the autonomic regulation system in the form of vasomotor cardiovascular center activation (LF spectral components) and non-specific stress response, which depends on the actual autonomic balance [Breus, Baevsky, 2002]. Within the project "Mars-500" the parallel medical-ecological studies were conducted in 10 groups (10-16 people), that lived in different regions of the world under the influence of various environmental factors - climatic, geographic, industrial, social and other. It allowed us to obtain a sufficiently large number of variants of adaptive reactions caused by differences in external impacts. The main research method was the heart rate variability (HRV) analysis in short ECG samples (5 minutes) for assessing heart rate chronostructure and functional status of autonomic regulation. Results of studies have demonstrated that environmental loads on the regulatory mechanisms is higher in the northern and north-eastern regions of Russia - Magadan and Syktyvkar. Stress-index of regulatory systems and adaptive risk indicator is significantly higher in these groups [Baevsky, Berseneva, 2013]. The preliminary search of weather factors (atmospheric pressure, air temperature, humidity and magnetic index Kp) influence on the autonomic regulation of heart rate showed that there are no any significant changes and relationships in the entire group of participants. We have assumed that the character of adaptive responses, including responses to changing weather and geomagnetic conditions, is associated with the individual characteristics and the initial functional state of autonomic regulation. To test this hypothesis, we have identified two groups of subjects with different autonomic balance. The first group included individuals with a pronounced predominance of sympathetic regulation (n = 127), the second - with a

  5. Environmental occurrences

    International Nuclear Information System (INIS)

    Black, D.G.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report summarizes the onsite and offsite releases of radioactive and regulated materials. The specific agencies notified of the releases depended on the type, amount, and location of the individual occurrences. The more significant of these off-normal environmental occurrences are summarized in this section

  6. Identifying gene coexpression networks underlying the dynamic regulation of wood-forming tissues in Populus under diverse environmental conditions.

    Science.gov (United States)

    Zinkgraf, Matthew; Liu, Lijun; Groover, Andrew; Filkov, Vladimir

    2017-06-01

    Trees modify wood formation through integration of environmental and developmental signals in complex but poorly defined transcriptional networks, allowing trees to produce woody tissues appropriate to diverse environmental conditions. In order to identify relationships among genes expressed during wood formation, we integrated data from new and publically available datasets in Populus. These datasets were generated from woody tissue and include transcriptome profiling, transcription factor binding, DNA accessibility and genome-wide association mapping experiments. Coexpression modules were calculated, each of which contains genes showing similar expression patterns across experimental conditions, genotypes and treatments. Conserved gene coexpression modules (four modules totaling 8398 genes) were identified that were highly preserved across diverse environmental conditions and genetic backgrounds. Functional annotations as well as correlations with specific experimental treatments associated individual conserved modules with distinct biological processes underlying wood formation, such as cell-wall biosynthesis, meristem development and epigenetic pathways. Module genes were also enriched for DNase I hypersensitivity footprints and binding from four transcription factors associated with wood formation. The conserved modules are excellent candidates for modeling core developmental pathways common to wood formation in diverse environments and genotypes, and serve as testbeds for hypothesis generation and testing for future studies. No claim to original US government works. New Phytologist © 2017 New Phytologist Trust.

  7. Differences in the regulation of chemicals and radionuclides

    International Nuclear Information System (INIS)

    Travis, C.C.

    1993-12-01

    Government regulations limiting public exposure to radionuclides and chemicals have historically been developed by regulatory agencies using different approaches with the result that levels of protection vary for the two classes of contaminants. These differences create difficulties in determining equitable regulatory measures when both radionuclides and chemical pollutants are involved. Generally, radiation exposure is not regulated as stringently as chemical exposure (Travis et al, 1989). The International commission on Radiological Protection (ICRP) recommends limiting excess environmental radiation exposure to the general public to 100 millirem per year (mrem/yr) (ICRP, 1991), a lifetime cancer risk of about 3.5E-3. An acceptable level of risk for chemical exposures is generally considered to be below 1E-6. Differences in regulatory approach for radionuclides and chemicals evoke debate over why they are different and which regulation strategy is better. Because these pollutants often coexist (mixed waste sites, contaminated metals and facilities, etc.), it is important to analyze inconsistencies in the regulation of chemicals and radionuclides and establish a more consistent approach to defining an acceptable level of exposure for these contaminants

  8. Annual Site Environmental Report

    Energy Technology Data Exchange (ETDEWEB)

    Holden, Gene

    1999-09-23

    This report provides information about environmental programs and compliance with environmental regulations in calendar year 1998 (CY98) at the Stanford Linear Accelerator Center (SLAC). The most significant information in this report is summarized in the following sections: (1) Environmental Compliance--Section 2 contains the complete Environmental Compliance information; (2) Environmental Non-Radiological Program--Section 3 contains the complete Environmental Non-Radiological information; and (3) Environmental Radiological Program--Section 4 contains the complete Environmental Radiological information.

  9. Elements of an environmental decision support system for seasonal wetland salt management in a river basin subjected to water quality regulation

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, N.W.T.

    2009-06-01

    Seasonally managed wetlands in the Grasslands Basin on the west-side of California's San Joaquin Valley provide food and shelter for migratory wildfowl during winter months and sport for waterfowl hunters during the annual duck season. Surface water supply to these wetlands contain salt which, when drained to the San Joaquin River during the annual drawdown period, can negatively impact water quality and cause concern to downstream agricultural riparian water diverters. Recent environmental regulation, limiting discharges salinity to the San Joaquin River and primarily targeting agricultural non-point sources, now also targets return flows from seasonally managed wetlands. Real-time water quality management has been advocated as a means of continuously matching salt loads discharged from agricultural, wetland and municipal operations to the assimilative capacity of the San Joaquin River. Past attempts to build environmental monitoring and decision support systems (EDSS's) to implement this concept have enjoyed limited success for reasons that are discussed in this paper. These reasons are discussed in the context of more general challenges facing the successful implementation of a comprehensive environmental monitoring, modelling and decision support system for the San Joaquin River Basin.

  10. Environmental regulation, productive efficiency and cost of pollution abatement: a case study of the sugar industry in India.

    Science.gov (United States)

    Murty, M N; Kumar, Surender; Paul, Mahua

    2006-04-01

    In this paper the input distance function is estimated for the Indian Sugar industry under alternative assumptions of weak and strong disposability of bad outputs. The estimated distance function is used to make the estimates of environmental efficiency, Malmquist productivity index and shadow prices of pollutants. The technical efficiency measure estimated under the assumption of weak disposability of bad outputs is utilized to test the Porter hypothesis. Marginal costs of pollution abatement functions are estimated for different pollutants of water. Pollutant specific taxes are computed using the tax-standards method.

  11. Environmental gradients regulate the spatio-temporal variability of phytoplankton assemblages in the Can Gio Mangrove Biosphere Reserve, Vietnam

    Science.gov (United States)

    Pham, Thanh-Luu

    2017-12-01

    This paper covers spatial and temporal variation in phytoplankton communities and physico-chemical variables in the Can Gio Mangrove Biosphere Reserve (CGMBR), Vietnam, based on field measurement conducted monthly at nine stations during February 2009 to January 2010. Species diversity, richness and phytoplankton abundance were calculated. Canonical Correspondence Analysis (CCA) was used to investigate the relationship between environmental factors and phytoplankton community. A total of 126 species were recorded with a clear dominance of Bacillariophyceae, which formed about 76.4% of the total phytoplankton counts with an annual average of 44.900 cells/L. Other algal classes like Dinophyceae, Cyanophyceae and Chrysophyceae sustained low counts, forming collectively about 14% of the total abundance of phytoplankton. Although Chaetoceros and Coscinodiscus were the most dominant genera, Schroederella and Skeletonema showed high abundance during the studied period. Among the nine environmental parameters tested in this study, salinity, nitrate and ammonium were found to be significantly different between two seasons. On the other hand, no significant difference was found between stations for the studied variables. Results of CCA indicated that phytoplankton assemblage in the CGMBR was influenced by salinity, nitrate and phosphate concentration. This is the first study simultaneously investigating the phytoplankton communities and their environment in this area and it is essential in order to set up the baseline of future studies.

  12. A Novel Small RNA Regulates Tolerance and Virulence in Shigella flexneri by Responding to Acidic Environmental Changes

    Directory of Open Access Journals (Sweden)

    Ligui eWang

    2016-03-01

    Full Text Available Shigella flexneri is an important cause of bacillary dysentery in developing countries. Small regulatory RNAs (sRNAs play essential roles in diverse cellular processes. We found a novel sRNA Ssr1 based on RT-PCR, northern blot, and 5´RACE in S. flexneri. Ssr1 responds to acidic environmental changes, as shown by a strong linear correlation between the pH value and Ssr1 expression (R = 0.785, P < 0.05 using the qRT-PCR method. Deletion of Ssr1 results in growth retardation at pH values ranging from 5.0 to 7.0 (P < 0.05, and the survival rate was reduced by 22% in acidic conditions (pH 3.0. Additionally, virulence was significantly increased in an Ssr1 mutant strain, as revealed in a murine lung invasion model and survival model assays. By using the sTarPicker method and proteomic analysis, we considered that DnaK, which is a major factor that confers acidic stress tolerance, may be a direct target of Ssr1. We also found that Ssr1 may enhance virulence by directly targeting OmpA; this leads to altered expression of genes in the type three secretion system. This work provides new insight into the mechanism of adaptation to environmental stress and into the pathogenesis of Shigella.

  13. Technological innovation and environmental regulation at the petroleum refining industry: the Paulinia refinery case; Inovacao tecnologica e regulacao ambiental na industria de refino de petroleo: o caso da Refinaria de Paulinia

    Energy Technology Data Exchange (ETDEWEB)

    Azevedo, Adalberto Mantovani Martiniano de; Pereira, Newton Mueller [Universidade Estadual de Campinas (UNICAMP), Campinas, SP (Brazil). Inst. de Geociencias. Dept. de Politica Cientifica e Tecnologica]. E-mails: adalba@ige.unicamp.br; newpe@ige.unicamp.br

    2006-07-01

    This article discusses the influence of environmental regulation on the adoption of new production techniques and on the improvement of existing techniques in the refining petroleum industry, namely at the Paulinia refinery (REPLAN). Describes the techniques adopted in order to fit refining processes into the regulation about environmental impacts (related to the protection of resources like water, air and soil), and also techniques adopted in order to produce less pollutant diesel and gasoline. This article has support on bibliographic research and data collected in REPLAN and CENPES, which permit characterize technologies adopted in REPLAN at the end of the 90s and the regulatory rules that drive them. The regulation is presented under an evolutionary approach, considering that technology develops along whit the socio-economic context, the environmental regulation is a related element which determines the search and selection of technologies able to comply with regulation ensuring economic viability. Regulation is also a determinant factor for the adoption of innovations in the refining industry. Specifically in REPLAN, the environmental regulation has required large investments in order to comply processes and products with the established standards. (author)

  14. Regulators as agents: Modelling personality and power as evidence is brokered to support decisions on environmental risk

    Energy Technology Data Exchange (ETDEWEB)

    Davies, G.J. [Cranfield University, Centre for Environmental Risks and Futures, School of Applied Sciences, Cranfield MK43 0AL (United Kingdom); Kendall, G. [University of Nottingham, School of Computer Science, Nottingham NG8 1BB (United Kingdom); University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan (Malaysia); Soane, E. [London School of Economics and Political Science, Department of Management, London WC2A 2AE (United Kingdom); Li, J. [University of Nottingham, School of Computer Science, Nottingham NG8 1BB (United Kingdom); Rocks, S.A.; Jude, S.R. [Cranfield University, Centre for Environmental Risks and Futures, School of Applied Sciences, Cranfield MK43 0AL (United Kingdom); Pollard, S.J.T., E-mail: s.pollard@cranfield.ac.uk [Cranfield University, Centre for Environmental Risks and Futures, School of Applied Sciences, Cranfield MK43 0AL (United Kingdom)

    2014-01-01

    Complex regulatory decisions about risk rely on the brokering of evidence between providers and recipients, and involve personality and power relationships that influence the confidence that recipients may place in the sufficiency of evidence and, therefore, the decision outcome. We explore these relationships in an agent-based model; drawing on concepts from environmental risk science, decision psychology and computer simulation. A two-agent model that accounts for the sufficiency of evidence is applied to decisions about salt intake, animal carcass disposal and radioactive waste. A dynamic version of the model assigned personality traits to agents, to explore their receptivity to evidence. Agents with ‘aggressor’ personality sets were most able to imbue fellow agents with enhanced receptivity (with ‘avoider’ personality sets less so) and clear confidence in the sufficiency of evidence. In a dynamic version of the model, when both recipient and provider were assigned the ‘aggressor’ personality set, this resulted in 10 successful evidence submissions in 71 days, compared with 96 days when both agents were assigned the ‘avoider’ personality set. These insights suggest implications for improving the efficiency and quality of regulatory decision making by understanding the role of personality and power. - Highlights: •The role of personality and power in regulatory decision-making is poorly represented. •We built a rudimentary two-agent model to explore environmental risk decisions. •Our two agent model accounted for decisions about the sufficiency of evidence. •We examined the influence personality and power has on confidence gained. •By giving agents personality we might predict the time taken to reach consensus.

  15. Toward a workable biosafety system for regulating genetically modified organisms in Ethiopia: balancing conservation and competitiveness.

    Science.gov (United States)

    Abraham, Adane

    2013-01-01

    On September 9, 2009, Ethiopia enacted a highly restrictive biosafety law firmly based on precautionary principles as a foundation for its GMO regulation system. Its drafting process, led by the country's Environmental Protection Authority, was judged as biased, focusing only on protecting the environment from perceived risks, giving little attention to potential benefits of GMOs. Many of its provisions are very stringent, exceeding those of Cartagena Protocol on Biosafety, while others cannot be fulfilled by applicants, collectively rendering the emerged biosafety system unworkable. These provisions include requirements for advance informed agreement and rigorous socioeconomic assessment in risk evaluation for all GMO transactions, including contained research use-which requires the head of the competent national authority of the exporting country to take full responsibility for GMO-related information provided-and stringent labeling, insurance and monitoring requirements for all GMO activities. Furthermore, there is no provision to establish an independent national biosafety decision-making body(ies). As a result, foreign technology owners that provide highly demanded technologies like Bt cotton declined to work with Ethiopia. There is a fear that the emerged biosafety system might also continue to suppress domestic genetic engineering research and development. Thus, to benefit from GMOs, Ethiopia has to revise its biosafety system, primarily by making changes to some provisions of the law in a way that balances its diverse interests of conserving biodiversity, protecting the environment and enhancing competition in agricultural and other economic sectors.

  16. Environmental statement

    International Nuclear Information System (INIS)

    Iannone, G.

    1995-01-01

    This paper focusses on one of the basic points of EU (European Union) regulation 1863/1993, namely the disclosure of information via an environmental statement. The author examines the uses to which the data may be put, emphasizes the importance of the environmental statement's contents and addressee, and describes the key function of external data control by an environmental verifier. Lastly, the author shows that the environmental statement could replace a number of documents that companies are now required to file with various agencies; this would reduce their administrative burden

  17. Management, regulation and environmental impacts of nitrogen fertilization in northwestern Europe under the Nitrates Directive; a benchmark study

    Directory of Open Access Journals (Sweden)

    H. J. M. van Grinsven

    2012-12-01

    Full Text Available Implementation of the Nitrates Directive (NiD and its environmental impacts were compared for member states in the northwest of the European Union (Ireland, United Kingdom, Denmark, the Netherlands, Belgium, Northern France and Germany. The main sources of data were national reports for the third reporting period for the NiD (2004–2007 and results of the MITERRA-EUROPE model. Implementation of the NiD in the considered member states is fairly comparable regarding restrictions for where and when to apply fertilizer and manure, but very different regarding application limits for N fertilization. Issues of concern and improvement of the implementation of the NiD are accounting for the fertilizer value of nitrogen in manure, and relating application limits for total nitrogen (N to potential crop yield and N removal. The most significant environmental effect of the implementation of the NiD since 1995 is a major contribution to the decrease of the soil N balance (N surplus, particularly in Belgium, Denmark, Ireland, the Netherlands and the United Kingdom. This decrease is accompanied by a modest decrease of nitrate concentrations since 2000 in fresh surface waters in most countries. This decrease is less prominent for groundwater in view of delayed response of nitrate in deep aquifers. In spite of improved fertilization practices, the southeast of the Netherlands, the Flemish Region and Brittany remain to be regions of major concern in view of a combination of a high nitrogen surplus, high leaching fractions to groundwater and tenacious exceedance of the water quality standards. On average the gross N balance in 2008 for the seven member states in EUROSTAT and in national reports was about 20 kg N ha−1 yr−1 lower than by MITERRA. The major cause is higher estimates of N removal in national reports which can amount to more than 50 kg N ha−1 yr−1. Differences between procedures in member states to

  18. Management, regulation and environmental impacts of nitrogen fertilization in northwestern Europe under the Nitrates Directive; a benchmark study

    Science.gov (United States)

    van Grinsven, H. J. M.; ten Berge, H. F. M.; Dalgaard, T.; Fraters, B.; Durand, P.; Hart, A.; Hofman, G.; Jacobsen, B. H.; Lalor, S. T. J.; Lesschen, J. P.; Osterburg, B.; Richards, K. G.; Techen, A.-K.; Vertès, F.; Webb, J.; Willems, W. J.

    2012-12-01

    Implementation of the Nitrates Directive (NiD) and its environmental impacts were compared for member states in the northwest of the European Union (Ireland, United Kingdom, Denmark, the Netherlands, Belgium, Northern France and Germany). The main sources of data were national reports for the third reporting period for the NiD (2004-2007) and results of the MITERRA-EUROPE model. Implementation of the NiD in the considered member states is fairly comparable regarding restrictions for where and when to apply fertilizer and manure, but very different regarding application limits for N fertilization. Issues of concern and improvement of the implementation of the NiD are accounting for the fertilizer value of nitrogen in manure, and relating application limits for total nitrogen (N) to potential crop yield and N removal. The most significant environmental effect of the implementation of the NiD since 1995 is a major contribution to the decrease of the soil N balance (N surplus), particularly in Belgium, Denmark, Ireland, the Netherlands and the United Kingdom. This decrease is accompanied by a modest decrease of nitrate concentrations since 2000 in fresh surface waters in most countries. This decrease is less prominent for groundwater in view of delayed response of nitrate in deep aquifers. In spite of improved fertilization practices, the southeast of the Netherlands, the Flemish Region and Brittany remain to be regions of major concern in view of a combination of a high nitrogen surplus, high leaching fractions to groundwater and tenacious exceedance of the water quality standards. On average the gross N balance in 2008 for the seven member states in EUROSTAT and in national reports was about 20 kg N ha-1 yr-1 lower than by MITERRA. The major cause is higher estimates of N removal in national reports which can amount to more than 50 kg N ha-1 yr-1. Differences between procedures in member states to assess nitrogen balances and water quality and a lack of cross

  19. Energy and environmental profile of the U.S. iron and steel industry

    International Nuclear Information System (INIS)

    Margolis, N.; Sousa, L.

    1997-01-01

    The iron and steel industry, which accounts for between two and three percent of all energy consumed in this country, is also striving to improve its energy efficiency. The amount of energy required to produce a ton of steel has decreased by more than 40% since 1975. This reduction has been accomplished in part through adoption of more energy-efficient and productive processing steps. However, the capital to invest in new technologies is increasingly limited, especially as the costs of environmental control continue to rise. Other than foreign competition, the biggest challenge facing the industry today is compliance with environmental regulations. The Clean Air Act and the Resource Conservation and Recovery Act have had significant impacts on the industry. Since 1970, the industry has invested approximately $6 billion in pollution control systems. The industry spent approximately $230 million in both 1993 and 1994 on capital expenditures for pollution abatement. In a typical year, 15% of the industry's capital investments go to environmental projects. The industry faces even more challenges in the future as new, more stringent regulations are enacted. Topics covered here are: market trends and statistics; energy and materials consumption; and an environmental overview

  20. Cellular manganese content is developmentally regulated in human dopaminergic neurons

    Science.gov (United States)

    Kumar, Kevin K.; Lowe, Edward W., Jr.; Aboud, Asad A.; Neely, M. Diana; Redha, Rey; Bauer, Joshua A.; Odak, Mihir; Weaver, C. David; Meiler, Jens; Aschner, Michael; Bowman, Aaron B.

    2014-10-01

    Manganese (Mn) is both an essential biological cofactor and neurotoxicant. Disruption of Mn biology in the basal ganglia has been implicated in the pathogenesis of neurodegenerative disorders, such as parkinsonism and Huntington's disease. Handling of other essential metals (e.g. iron and zinc) occurs via complex intracellular signaling networks that link metal detection and transport systems. However, beyond several non-selective transporters, little is known about the intracellular processes regulating neuronal Mn homeostasis. We hypothesized that small molecules that modulate intracellular Mn could provide insight into cell-level Mn regulatory mechanisms. We performed a high throughput screen of 40,167 small molecules for modifiers of cellular Mn content in a mouse striatal neuron cell line. Following stringent validation assays and chemical informatics, we obtained a chemical `toolbox' of 41 small molecules with diverse structure-activity relationships that can alter intracellular Mn levels under biologically relevant Mn exposures. We utilized this toolbox to test for differential regulation of Mn handling in human floor-plate lineage dopaminergic neurons, a lineage especially vulnerable to environmental Mn exposure. We report differential Mn accumulation between developmental stages and stage-specific differences in the Mn-altering activity of individual small molecules. This work demonstrates cell-level regulation of Mn content across neuronal differentiation.

  1. Master Plan for Environmental Education

    Science.gov (United States)

    1992-10-01

    This Task investigated the general question of environmental education from the standpoint of the shipyard industry. Personal interviews were...a listing of the environmental regulations and statutes that bear on environmental education . Analysis of the findings suggests that environmental ... education programs in most shipyards are limited to what is required by the regulations. Little or no additional environmental education is being

  2. Seed dormancy cycling in Arabidopsis: chromatin remodelling and regulation of DOG1 in response to seasonal environmental signals.

    Science.gov (United States)

    Footitt, Steven; Müller, Kerstin; Kermode, Allison R; Finch-Savage, William E

    2015-02-01

    The involvement of chromatin remodelling in dormancy cycling in the soil seed bank (SSB) is poorly understood. Natural variation between the winter and summer annual Arabidopsis ecotypes Cvi and Bur was exploited to investigate the expression of genes involved in chromatin remodelling via histone 2B (H2B) ubiquitination/de-ubiquitination and histone acetylation/deacetylation, the repressive histone methyl transferases CURLY LEAF (CLF) and SWINGER (SWN), and the gene silencing repressor ROS1 (REPRESSOR OF SILENCING1) and promoter of silencing KYP/SUVH4 (KRYPTONITE), during dormancy cycling in the SSB. ROS1 expression was positively correlated with dormancy while the reverse was observed for CLF and KYP/SUVH4. We propose ROS1 dependent repression of silencing and a sequential requirement of CLF and KYP/SUVH4 dependent gene repression and silencing for the maintenance and suppression of dormancy during dormancy cycling. Seasonal expression of H2B modifying genes was correlated negatively with temperature and positively with DOG1 expression, as were histone acetyltransferase genes, with histone deacetylases positively correlated with temperature. Changes in the histone marks H3K4me3 and H3K27me3 were seen on DOG1 (DELAY OF GERMINATION1) in Cvi during dormancy cycling. H3K4me3 activating marks remained stable along DOG1. During relief of dormancy, H3K27me3 repressive marks slowly accumulated and accelerated on exposure to light completing dormancy loss. We propose that these marks on DOG1 serve as a thermal sensing mechanism during dormancy cycling in preparation for light repression of dormancy. Overall, chromatin remodelling plays a vital role in temporal sensing through regulation of gene expression. © 2014 The Authors The Plant Journal published by Society for Experimental Biology and John Wiley & Sons Ltd.

  3. Functional regulation of Pb-Ti/MoS{sub 2} composite coatings for environmentally adaptive solid lubrication

    Energy Technology Data Exchange (ETDEWEB)

    Ren, Siming [Key Laboratory of Marine Materials and Related Technologies, Key Laboratory of Marine Materials and Protective Technologies of Zhejiang Province, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201 (China); University of Chinese Academy of Sciences, Beijing 100039 (China); Li, Hao [Key Laboratory of Advanced Technologies of Materials (Ministry of Education), School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031 (China); Cui, Mingjun [Key Laboratory of Marine Materials and Related Technologies, Key Laboratory of Marine Materials and Protective Technologies of Zhejiang Province, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201 (China); University of Chinese Academy of Sciences, Beijing 100039 (China); Wang, Liping, E-mail: wangliping@nimte.ac.cn [Key Laboratory of Marine Materials and Related Technologies, Key Laboratory of Marine Materials and Protective Technologies of Zhejiang Province, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201 (China); Pu, Jibin, E-mail: pujibin@nimte.ac.cn [Key Laboratory of Marine Materials and Related Technologies, Key Laboratory of Marine Materials and Protective Technologies of Zhejiang Province, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201 (China)

    2017-04-15

    Highlights: • Co-doped Pb-Ti/MoS{sub 2} composite coatings were successfully fabricated by unbalanced magnetron sputtering system. • Co-doped Pb-Ti/MoS{sub 2} composite coatings showed lower friction coefficient and longer wear life in both humid and vacuum environments than that of single-doped ones. • The wear behaviours of Pb-Ti/MoS{sub 2} composite coatings with the increase of Pb content is in accordance with the variation in H/E ratio that higher H/E is corresponding to the lower wear rate of coating. - Abstract: The lubrication of molybdenum disulfide coatings has commonly been limited by the application environments, for instance, the crystal MoS{sub 2} are easily affected by water to form MoO{sub 3} that causes a higher friction coefficient and short lifetime. Therefore, to improve the tribolgical performance of MoS{sub 2} in high humidity condition, the co-doped Pb-Ti/MoS{sub 2} composite coatings are deposited by unbalanced magnetron sputtering system. The design of the co-doping elements in MoS{sub 2}-based coatings can not only maintain the characteristic of low humidity-sensitivity as the Ti/MoS{sub 2} coating but also improve the mechanical properties and tribological performance of coatings as a comparison with single-doped ones. Moreover, the ultra-low friction coefficient with a minimum value of 0.006 under the vacuum condition is achieved for Pb-Ti/MoS{sub 2} composite coating containing about 4.6 at.% Pb, depending on the densification structure of coating. Intriguingly, the wear behaviours of Pb-Ti/MoS{sub 2} composite coatings are in accordance with the variation in H/E (hardness to the elastic modulus) ratio that the coating with higher H/E exhibits lower wear rate. These results demonstrate that the lubricating properties of MoS{sub 2} coatings in both humid environment and vacuum condition can be achieved through the Pb and Ti co-doped, which is of great significant for developing MoS{sub 2} coatings as the environmentally adaptive

  4. WARM JUPITERS NEED CLOSE ''FRIENDS'' FOR HIGH-ECCENTRICITY MIGRATION—A STRINGENT UPPER LIMIT ON THE PERTURBER'S SEPARATION

    Energy Technology Data Exchange (ETDEWEB)

    Dong, Subo [Kavli Institute for Astronomy and Astrophysics, Peking University, Yi He Yuan Road 5, Hai Dian District, Beijing 100871 (China); Katz, Boaz; Socrates, Aristotle [Institute for Advanced Study, 1 Einstein Dr., Princeton, NJ 08540 (United States)

    2014-01-20

    We propose a stringent observational test on the formation of warm Jupiters (gas-giant planets with 10 days ≲ P ≲ 100 days) by high-eccentricity (high-e) migration mechanisms. Unlike hot Jupiters, the majority of observed warm Jupiters have pericenter distances too large to allow efficient tidal dissipation to induce migration. To access the close pericenter required for migration during a Kozai-Lidov cycle, they must be accompanied by a strong enough perturber to overcome the precession caused by general relativity, placing a strong upper limit on the perturber's separation. For a warm Jupiter at a ∼ 0.2 AU, a Jupiter-mass (solar-mass) perturber is required to be ≲ 3 AU (≲ 30 AU) and can be identified observationally. Among warm Jupiters detected by radial velocities (RVs), ≳ 50% (5 out of 9) with large eccentricities (e ≳ 0.4) have known Jovian companions satisfying this necessary condition for high-e migration. In contrast, ≲ 20% (3 out of 17) of the low-e (e ≲ 0.2) warm Jupiters have detected additional Jovian companions, suggesting that high-e migration with planetary perturbers may not be the dominant formation channel. Complete, long-term RV follow-ups of the warm-Jupiter population will allow a firm upper limit to be put on the fraction of these planets formed by high-e migration. Transiting warm Jupiters showing spin-orbit misalignments will be interesting to apply our test. If the misalignments are solely due to high-e migration as commonly suggested, we expect that the majority of warm Jupiters with low-e (e ≲ 0.2) are not misaligned, in contrast with low-e hot Jupiters.

  5. Cosmetic Regulations: A Comparative Study.

    Science.gov (United States)

    Suhag, Jyoti; Dureja, Harish

    2015-01-01

    The regulatory framework, compliance requirement, efficacy, safety, and marketing of cosmetic products are considered the most important factors for growth of the cosmetic industry. There are different regulatory bodies across the globe that have their own insights for regulation; moreover, governments such as the United States, European Union, and Japan follow a stringent regulatory framework, whereas cosmetics are not so much strictly regulated in countries such as India, Brazil, and China. The alignment of a regulatory framework will play a significant role in the removal of barriers to trade, growth of market at an international level, innovation in the development and presentation of new products, and most importantly safety and efficacy of the marketed products. The present contribution gives insight into the important cosmetic regulations in areas of premarket approval, ingredient control, and labeling and warnings, with a special focus on the cosmetic regulatory environments in the United States, European Union, Japan, and India. Most importantly, the authors highlight the dark side of cosmetics associated with allergic reactions and even skin cancer. The importance of cosmetic regulations has been highlighted by dint of which the society can be healthier, accomplished by more stringent and harmonized regulations.

  6. Keratinocyte-derived IL-24 plays a role in the positive feedback regulation of epidermal inflammation in response to environmental and endogenous toxic stressors.

    Science.gov (United States)

    Jin, Sun Hee; Choi, Dalwoong; Chun, Young-Jin; Noh, Minsoo

    2014-10-15

    Keratinocytes are the major cellular components of human epidermis and play a key role in the modulating cutaneous inflammation and toxic responses. In human chronic skin diseases, the common skin inflammatory phenotypes like skin barrier disruption and epidermal hyperplasia are manifested in epidermal keratinocytes by interactions with T helper (Th) cells. To find a common gene expression signature of human keratinocytes in chronic skin diseases, we performed a whole genome microarray analysis on normal human epidermal keratinocytes (NHKs) treated with IFNγ, IL-4, IL-17A or IL-22, major cytokines from Th1, Th2, Th17 or Th22 cells, respectively. The microarray results showed that the four genes, IL-24, PDZK1IP1, H19 and filaggrin, had common expression profiles in NHKs exposed to Th cell cytokines. In addition, the acute phase pro-inflammatory cytokines, IL-1β, IL-6 and TNFα, also change the gene transcriptional profile of IL-24, PDZK1IP1, H19, and filaggrin in NHKs as those of Th cytokines. Therefore, the signature gene set, consisting of IL-24, PDZK1IP1, H19, and filaggrin, provides essential insights for understanding the process of cutaneous inflammation and toxic responses. We demonstrate that environmental toxic stressors, such as chemical irritants and ultraviolet irradiation stimulate the production of IL-24 in NHKs. IL-24 stimulates the JAK1-STAT3 and MAPK pathways in NHKs, and promotes the secretion of pro-inflammatory mediators IL-8, PGE2, and MMP-1. These results suggest that keratinocyte-derived IL-24 participates in the positive feedback regulation of epidermal inflammation in response to both endogenous and environmental toxic stressors. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Physical activity and environmental enrichment regulate the generation of neural precursors in the adult mouse substantia nigra in a dopamine-dependent manner

    Directory of Open Access Journals (Sweden)

    Klaissle Philipp

    2012-10-01

    Full Text Available Abstract Background Parkinson’s disease is characterized by a continuous loss of neurons within the substantia nigra (SN leading to a depletion of dopamine. Within the adult SN as a non-neurogenic region, cells with mainly oligodendrocytic precursor characteristics, expressing the neuro-glial antigen-2 (NG2 are continuously generated. Proliferation of these cells is altered in animal models of Parkinson’s disease (PD. Exercise and environmental enrichment re-increase proliferation of NG2+ cells in PD models, however, a possible mechanistic role of dopamine for this increase is not completely understood. NG2+ cells can differentiate into oligodendrocytes but also into microglia and neurons as observed in vitro suggesting a possible hint for endogenous regenerative capacity of the SN. We investigated the role of dopamine in NG2-generation and differentiation in the adult SN stimulated by physical activity and environmental enrichment. Results We used the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP-model for dopamine depletion and analysed newborn cells in the SN at different maturation stages and time points depending on voluntary physical activity, enriched environment and levodopa-treatment. We describe an activity- induced increase of new NG2-positive cells and also mature oligodendrocytes in the SN of healthy mice. Running and enriched environment refused to stimulate NG2-generation and oligodendrogenesis in MPTP-mice, an effect which could be reversed by pharmacological levodopa-induced rescue. Conclusion We suggest dopamine being a key regulator for activity-induced generation of NG2-cells and oliogodendrocytes in the SN as a potentially relevant mechanism in endogenous nigral cellular plasticity.

  8. NPR-9, a Galanin-Like G-Protein Coupled Receptor, and GLR-1 Regulate Interneuronal Circuitry Underlying Multisensory Integration of Environmental Cues in Caenorhabditis elegans.

    Directory of Open Access Journals (Sweden)

    Jason C Campbell

    2016-05-01

    Full Text Available C. elegans inhabit environments that require detection of diverse stimuli to modulate locomotion in order to avoid unfavourable conditions. In a mammalian context, a failure to appropriately integrate environmental signals can lead to Parkinson's, Alzheimer's, and epilepsy. Provided that the circuitry underlying mammalian sensory integration can be prohibitively complex, we analyzed nematode behavioral responses in differing environmental contexts to evaluate the regulation of context dependent circuit reconfiguration and sensorimotor control. Our work has added to the complexity of a known parallel circuit, mediated by interneurons AVA and AIB, that integrates sensory cues and is responsible for the initiation of backwards locomotion. Our analysis of the galanin-like G-protein coupled receptor NPR-9 in C. elegans revealed that upregulation of galanin signaling impedes the integration of sensory evoked neuronal signals. Although the expression pattern of npr-9 is limited to AIB, upregulation of the receptor appears to impede AIB and AVA circuits to broadly prevent backwards locomotion, i.e. reversals, suggesting that these two pathways functionally interact. Galanin signaling similarly plays a broadly inhibitory role in mammalian models. Moreover, our identification of a mutant, which rarely initiates backwards movement, allowed us to interrogate locomotory mechanisms underlying chemotaxis. In support of the pirouette model of chemotaxis, organisms that did not exhibit reversal behavior were unable to navigate towards an attractant peak. We also assessed ionotropic glutamate receptor GLR-1 cell-specifically within AIB and determined that GLR-1 fine-tunes AIB activity to modify locomotion following reversal events. Our research highlights that signal integration underlying the initiation and fine-tuning of backwards locomotion is AIB and NPR-9 dependent, and has demonstrated the suitability of C. elegans for analysis of multisensory integration

  9. Environmental Humidity Regulates Effects of Experimental Warming on Vegetation Index and Biomass Production in an Alpine Meadow of the Northern Tibet.

    Science.gov (United States)

    Fu, Gang; Shen, Zhen Xi

    2016-01-01

    Uncertainty about responses of vegetation index, aboveground biomass (AGB) and gross primary production (GPP) limits our ability to predict how climatic warming will influence plant growth in alpine regions. A field warming experiment was conducted in an alpine meadow at a low (4313 m), mid- (4513 m) and high elevation (4693 m) in the Northern Tibet since May 2010. Growing season vapor pressure deficit (VPD), soil temperature (Ts) and air temperature (Ta) decreased with increasing elevation, while growing season precipitation, soil moisture (SM), normalized difference vegetation index (NDVI), soil adjusted vegetation index (SAVI), AGB and GPP increased with increasing elevation. The growing season Ta, Ts and VPD in 2015 was greater than that in 2014, while the growing season precipitation, SM, NDVI, SAVI, AGB and GPP in 2015 was lower than that in 2014, respectively. Compared to the mean air temperature and precipitation during the growing season in 1963-2015, it was a warmer and wetter year in 2014 and a warmer and drier year in 2015. Experimental warming increased growing season Ts, Ta,VPD, but decreased growing season SM in 2014-2015 at all the three elevations. Experimental warming only reduced growing season NDVI, SAVI, AGB and GPP at the low elevation in 2015. Growing season NDVI, SAVI, AGB and GPP increased with increasing SM and precipitation, but decreased with increasing VPD, indicating vegetation index and biomass production increased with environmental humidity. The VPD explained more variation of growing season NDVI, SAVI, AGB and GPP compared to Ts, Ta and SM at all the three elevations. Therefore, environmental humidity regulated the effect of experimental warming on vegetation index and biomass production in alpine meadows on the Tibetan Plateau.

  10. The role of environmental factors in regulating the development of cartilaginous grafts engineered using osteoarthritic human infrapatellar fat pad-derived stem cells.

    Science.gov (United States)

    Liu, Yurong; Buckley, Conor T; Downey, Richard; Mulhall, Kevin J; Kelly, Daniel J

    2012-08-01

    Engineering functional cartilaginous grafts using stem cells isolated from osteoarthritic human tissue is of fundamental importance if autologous tissue engineering strategies are to be used in the treatment of diseased articular cartilage. It has previously been demonstrated that human infrapatellar fat pad (IFP)-derived stem cells undergo chondrogenesis in pellet culture; however, the ability of such cells to generate functional cartilaginous grafts has not been adequately addressed. The objective of this study was to explore how environmental conditions regulate the functional development of cartilaginous constructs engineered using diseased human IFP-derived stem cells (FPSCs). FPSCs were observed to display a diminished chondrogenic potential upon encapsulation in a three-dimensional hydrogel compared with pellet culture, synthesizing significantly lower levels of glycosaminoglycan and collagen on a per cell basis. To engineer more functional cartilaginous grafts, we next explored whether additional biochemical and biophysical stimulations would enhance chondrogenesis within the hydrogels. Serum stimulation was observed to partially recover the diminished chondrogenic potential within hydrogel culture. Over 42 days, stem cells that had first been expanded in a low-oxygen environment proliferated extensively on the outer surface of the hydrogel in response to serum stimulation, assembling a dense type II collagen-positive cartilaginous tissue resembling that formed in pellet culture. The application of hydrostatic pressure did not further enhance extracellular matrix synthesis within the hydrogels, but did appear to alter the spatial accumulation of extracellular matrix leading to the formation of a more compact tissue with superior mechanically functionality. Further work is required in order to recapitulate the environmental conditions present during pellet culture within scaffolds or hydrogels in order to engineer more functional cartilaginous grafts using

  11. Combinatorial effects of environmental parameters on transcriptional regulation in Saccharomyces cerevisiae: A quantitative analysis of a compendium of chemostat-based transcriptome data

    Directory of Open Access Journals (Sweden)

    de Winde Johannes H

    2009-01-01

    Full Text Available Abstract Background Microorganisms adapt their transcriptome by integrating multiple chemical and physical signals from their environment. Shake-flask cultivation does not allow precise manipulation of individual culture parameters and therefore precludes a quantitative analysis of the (combinatorial influence of these parameters on transcriptional regulation. Steady-state chemostat cultures, which do enable accurate control, measurement and manipulation of individual cultivation parameters (e.g. specific growth rate, temperature, identity of the growth-limiting nutrient appear to provide a promising experimental platform for such a combinatorial analysis. Results A microarray compendium of 170 steady-state chemostat cultures of the yeast Saccharomyces cerevisiae is presented and analyzed. The 170 microarrays encompass 55 unique conditions, which can be characterized by the combined settings of 10 different cultivation parameters. By applying a regression model to assess the impact of (combinations of cultivation parameters on the transcriptome, most S. cerevisiae genes were shown to be influenced by multiple cultivation parameters, and in many cases by combinatorial effects of cultivation parameters. The inclusion of these combinatorial effects in the regression model led to higher explained variance of the gene expression patterns and resulted in higher function enrichment in subsequent analysis. We further demonstrate the usefulness of the compendium and regression analysis for interpretation of shake-flask-based transcriptome studies and for guiding functional analysis of (uncharacterized genes and pathways. Conclusion Modeling the combinatorial effects of environmental parameters on the transcriptome is crucial for understanding transcriptional regulation. Chemostat cultivation offers a powerful tool for such an approach.

  12. Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease.

    Science.gov (United States)

    Mirochnic, Sebastian; Wolf, Susanne; Staufenbiel, Matthias; Kempermann, Gerd

    2009-10-01

    An active lifestyle is to some degree protective against Alzheimer's disease (AD), but the biological basis for this benefit is still far from clear. We hypothesize that physical and cognitive activity increase a reserve for plasticity by increasing adult neurogenesis in the hippocampal dentate gyrus (DG). We thus assessed how age affects the response to activity in the murine APP23 model of AD compared with wild type (WT) controls and studied the effects of physical exercise (RUN) and environmental enrichment (ENR) in comparison with standard housing (CTR) at two different ages (6 months and 18 months) and in both genotypes. At 18 months, both activity paradigms reduced the hippocampal human Abeta1-42/Abeta1-40 ratio when compared with CTR, despite a stable plaque load in the hippocampus. At this age, both RUN and ENR increased the number of newborn granule cells in the DG of APP23 mice when compared with CTR, whereas the levels of regulation were equivalent to those in WT mice under the same housing conditions. At 6 months, however, neurogenesis in ENR but not RUN mice responded like the WT. Quantifying the number of cells at the doublecortin-positive stage in relation to the number of cells on postmitotic stages we found that ENR overproportionally increased the number of the DCX-positive "late" progenitor cells, indicative of an increased potential to recruit even more new neurons. In summary, the biological substrates for activity-dependent regulation of adult hippocampal neurogenesis were preserved in the APP23 mice. We thus propose that in this model, ENR even more than RUN might contribute to a "neurogenic reserve" despite a stable plaque load and that age affects the outcome of an interaction based on "activity." Copyright 2008 Wiley-Liss, Inc.

  13. Environmental Compliance Mechanisms

    NARCIS (Netherlands)

    Merkouris, Panagiotis; Fitzmaurice, Malgosia

    2017-01-01

    Compliance mechanisms can be found in treaties regulating such diverse issues as human rights, disarmament law, and environmental law. In this bibliography, the focus will be on compliance mechanisms of multilateral environmental agreements (MEAs). Compliance with norms of international

  14. Assessment of the environmental impact statement for the proposed expansion of the Olympic Dam operations at Roxby Downs

    International Nuclear Information System (INIS)

    1997-01-01

    This Environmental Assessment Report assesses the social, environmental and economic impact of the proposal by Western Mining Corporation (Olympic Dam Corporation) Pty Ltd. (WMC) to increase their production at Olympic Dam mine from 150,000t/a of copper and associated products to 350,000t/a by a phased expansion. The first phase would take production to approximately 200,000t/a. The report reviews the 1997 Environmental Impact Statement (EIS), public comments on the EIS, and the proponent's responses to these comments in the Supplement to the EIS. It also relies on information, comments and advice provided by appropriate South Australian and Commonwealth government agencies (through the joint assessment process) and previous studies undertaken in the region.The focus of the contents of this assessment report are: water usage; tailing management; radiation management; economic and employment estimates; EIS process, regulation and monitoring as well as flora, fauna and town management issues. This report also recognises that the Olympic Dam mine has been subject to previous environmental assessments which resulted in the environmental regime currently in place for the existing operations.It is concluded that the risks to the biophysical, historical, cultural and social environments from the proposed Olympic dam expansion are acceptable provided the mine continues to operate under stringent environmental control

  15. Keratinocyte-derived IL-24 plays a role in the positive feedback regulation of epidermal inflammation in response to environmental and endogenous toxic stressors

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Sun Hee [Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 151-742 (Korea, Republic of); Choi, Dalwoong [Department of Public Health Science, Korea University, Seoul 136-701 (Korea, Republic of); Chun, Young-Jin [College of Pharmacy, Chung-Ang University, Seoul 156-756 (Korea, Republic of); Noh, Minsoo, E-mail: minsoo@alum.mit.edu [Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 151-742 (Korea, Republic of)

    2014-10-15

    Keratinocytes are the major cellular components of human epidermis and play a key role in the modulating cutaneous inflammation and toxic responses. In human chronic skin diseases, the common skin inflammatory phenotypes like skin barrier disruption and epidermal hyperplasia are manifested in epidermal keratinocytes by interactions with T helper (Th) cells. To find a common gene expression signature of human keratinocytes in chronic skin diseases, we performed a whole genome microarray analysis on normal human epidermal keratinocytes (NHKs) treated with IFNγ, IL-4, IL-17A or IL-22, major cytokines from Th1, Th2, Th17 or Th22 cells, respectively. The microarray results showed that the four genes, IL-24, PDZK1IP1, H19 and filaggrin, had common expression profiles in NHKs exposed to Th cell cytokines. In addition, the acute phase pro-inflammatory cytokines, IL-1β, IL-6 and TNFα, also change the gene transcriptional profile of IL-24, PDZK1IP1, H19, and filaggrin in NHKs as those of Th cytokines. Therefore, the signature gene set, consisting of IL-24, PDZK1IP1, H19, and filaggrin, provides essential insights for understanding the process of cutaneous inflammation and toxic responses. We demonstrate that environmental toxic stressors, such as chemical irritants and ultraviolet irradiation stimulate the production of IL-24 in NHKs. IL-24 stimulates the JAK1-STAT3 and MAPK pathways in NHKs, and promotes the secretion of pro-inflammatory mediators IL-8, PGE2, and MMP-1. These results suggest that keratinocyte-derived IL-24 participates in the positive feedback regulation of epidermal inflammation in response to both endogenous and environmental toxic stressors. - Highlights: • Cutaneous inflammatory gene signature consists of PDZK1IP1, IL-24, H19 and filaggrin. • Pro-inflammatory cytokines increase IL-24 production in human keratinocytes. • Environmental toxic stressors increase IL-24 production in human keratinocytes. • IL-24 stimulates human keratinocytes to

  16. Final environmental and regulatory assessment of using asphalt as a sealant in mine shafts

    International Nuclear Information System (INIS)

    1987-01-01

    This report discusses the properties of asphalt, the current regulatory status governing asphalt and future regulatory implications which may be pertinent in using asphalt as a waterproof shaft sealant. An understanding of the inherent organic composition of asphalt, an increase in the number of health and environmental research publications conducted on asphalt and an examination of the apparent trend of regulatory agencies toward more stringent environmental regulation governing the use of organic materials suggests asphalt could become regulated at a future time. This would only occur, however, if asphalt was found to conform to the present regulatory definitions of pollutants, contaminants or hazardous substances or if asphalt was included on a regulated substance list. In this regard, the study points out that asphalt contains very low levels of hazardous poly-nuclear aromatics (PNA's). These levels are significantly lower than the levels present in coal tars, a substance known to contain high levels of hazardous PNA's. Asphalt, however, has the inherent potential of producing higher concentrations of PNA's if the adverse condition of cracking should occur during the refinery production stage or on-site preparation of the asphalt. Also, unless existing control technology is applied, emission levels of sulfur dioxide, carbon monoxide, particulates and volatile organic carbons from the on-site preparation facilities could approach the permissible health standard levels of EPA. The study indicates, however, that available literature is limited on these issues

  17. Major weapon system environmental life-cycle cost estimating for Conservation, Cleanup, Compliance and Pollution Prevention (C3P2)

    Science.gov (United States)

    Hammond, Wesley; Thurston, Marland; Hood, Christopher

    1995-01-01

    The Titan 4 Space Launch Vehicle Program is one of many major weapon system programs that have modified acquisition plans and operational procedures to meet new, stringent environmental rules and regulations. The Environmental Protection Agency (EPA) and the Department of Defense (DOD) mandate to reduce the use of ozone depleting chemicals (ODC's) is just one of the regulatory changes that has affected the program. In the last few years, public environmental awareness, coupled with stricter environmental regulations, has created the need for DOD to produce environmental life-cycle cost estimates (ELCCE) for every major weapon system acquisition program. The environmental impact of the weapon system must be assessed and budgeted, considering all costs, from cradle to grave. The Office of the Secretary of Defense (OSD) has proposed that organizations consider Conservation, Cleanup, Compliance and Pollution Prevention (C(sup 3)P(sup 2)) issues associated with each acquisition program to assess life-cycle impacts and costs. The Air Force selected the Titan 4 system as the pilot program for estimating life-cycle environmental costs. The estimating task required participants to develop an ELCCE methodology, collect data to test the methodology and produce a credible cost estimate within the DOD C(sup 3)P(sup 2) definition. The estimating methodology included using the Program Office weapon system description and work breakdown structure together with operational site and manufacturing plant visits to identify environmental cost drivers. The results of the Titan IV ELCCE process are discussed and expanded to demonstrate how they can be applied to satisfy any life-cycle environmental cost estimating requirement.

  18. Environmental Concerns, Environmental Policy and Green Investment

    OpenAIRE

    Xuexian Gao; Haidong Zheng

    2017-01-01

    Environmental regulators often use environmental policy to induce green investment by firms. However, if an environmental policy fails to exert a long-run effect on regulating the economic agents’ behavior, it may be more reasonable to think of the firm as the leader in the game, since the investment in green technology is usually a strategic decision. In this paper, we consider a three-stage Stackelberg game to address the interaction between a profit-maximizing firm (Stackelberg leader) fac...

  19. Grandfather regulations, new source bias, and state air toxics regulations

    International Nuclear Information System (INIS)

    Levinson, Arik

    1999-01-01

    This paper uses plant-level data from the Census of Manufactures and the variation in toxic air pollution regulations across states to measure the effects of laws that are more stringent for new sources of pollution than for existing sources (so-called 'grandfather' regulations). Of particular interest is the resulting 'new source bias' and its effects on capital vintage and investment. Two industries are examined: commercial printing, which has a local product market; and paint manufacturing, which has a more national market. In general, there seem to be no statistically significant differences in capital vintage or investment between plants in states that grandfather new sources of pollution, plants in states that have no air toxics regulations, and plants in states that regulate both new and existing sources

  20. Analysis of the environmental control technology for tar sand development

    Energy Technology Data Exchange (ETDEWEB)

    de Nevers, N.; Glenne, B.; Bryner, C.

    1979-06-01

    The environmental technology for control of air pollution, water pollution, and for the disposal, stabilization, and vegetation of the waste tar sand were thoroughly investigated. Although some difficulties may be encountered in any of these undertakings, it seems clear that the air and water pollution problems can be solved to meet any applicable standard. Currently there are two large-scale plants producing liquid fuels from tar sands in Alberta, Canada which use similar technology involving surface mining, hot water extraction, and surface disposal of waste sand. These projects all meet the Canadian environmental control regulations in force at the time they began. The largest US deposits of tar sands are much smaller than the Canadian; 95 percent are located in the state of Utah. Their economics do not appear as attractive as the Canadian deposits. The environmental control costs are not large enough to make an otherwise economic project uneconomic. The most serious environmental conflict likely to occur over the recovery of liquid fuels from the US deposits of tar sands is that caused by the proximity of the deposits to national parks, national monuments, and a national recreation area in Utah. These areas have very stringent air pollution requirements; and even if the air pollution control requirements can be met, there may still be adequate opposition to large-scale mining ventures in these areas to prevent their commercial exploitation. Another environmental constraint may be water rights availability.Essentially all of the water running in the Colorado river basin is now legally allocated. Barring new interpretations of the legality of water rights purchase, Utah tar sands developments should be able to obtain water by purchasing existing irrigation water rights.

  1. Site Environmental Report for 2014

    Energy Technology Data Exchange (ETDEWEB)

    Pauer, Ronald O. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Baskin, David [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Borglin, Ned [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Fox, Robert [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Harvey, Zachary [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Jelinski, John [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Thorson, Patrick [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Wehle, Petra [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Xu, Suying [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-09-01

    The annual Site Environmental Report documents Lawrence Berkeley National Laboratory’s performance in reducing its environmental impacts, progress toward cleaning up groundwater contamination, and compliance with applicable Department of Energy, federal, state, and local environmental regulations.

  2. UK: disputing boundaries of biotechnology regulation

    OpenAIRE

    Les Levidow; Susan Carr

    1996-01-01

    UK biotechnology regulation has developed ‘precautionary controls’ for GMO releases. Stringent legislation was drafted and eventually implemented by the Department of Environment (DoE). In parallel, the DoE established a broadly-based advisory committee, which included ecologists and an implicit public-interest representation. The committee was assigned the task to advise on the release of all “novel organisms” — a term which implies an analogy between GMOs and non-indigenous organisms. Copyr...

  3. Green taxes, blue taxes: A comparative study of the use of fiscal policy to promote environmental quality

    International Nuclear Information System (INIS)

    Shaw, C.L.

    1991-01-01

    Central governments are facing increasingly stringent demands to lead the clean-up of public resources. Historically, governments have chosen legislation and regulation to address these concerns and achieved mixed results, but another tool of public policy holds significant promise and is gaining ground in the policy debate: 'green' taxes. The potential of a tax system is to mitigate environmental externalities is explored. The theory of pollution tax is reviewed and a comparison of two country cases where taxes have been designed explicitly to reduce industrial effluents and improve the quality of fresh water resources is presented. If structures to approximate social costs are federally mandated and regionally implemented, a comprehensive tax system can constitute an integral part of an effective response to private spoliation of the commons. (author). 17 refs, 2 figs, 4 tabs

  4. Environmental compliance management system

    Energy Technology Data Exchange (ETDEWEB)

    Cason, A. [Dow Chemical Co., Midland, MI (United States); Larrinaga, L.

    1995-12-01

    A cross-functional team of environmental regulatory experts, plant managers, and plant engineers have been working since 1991 on the development, implementation and maintenance of the Environmental Compliance Management System. The Environmental Compliance Management System is a practical and accurate method of determining the applicability of the state and federal environmental regulations and of establishing standard and straightforward procedures to meet these requirements. The Environmental Compliance Management System allows individual manufacturing facilities to avoid the additional manpower that would be required to read, digest and decide on the applicability and plan of action to meet the requirements of all the environmental regulations.

  5. Environmental policy in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Tsuru, Shigeto; Weidner, H. (eds.)

    1989-01-01

    This book deals in English with the most important features of Japanese environmental policy in a number of individual articles by different authors. The various sections report on: 1. History and organization of environmental policy; 2. The role of non-governmental actors in environmental policy (large industries); 3. Special features of environmental policies and problems; 4. Classical pollution control areas: Regulations and effects; 5. Environmental problems in a broader perspective (nature conservation); 6. Policy areas with influence on environmental quality; 7. Environmental monitoring and reporting; 8. Japanese environmental policy in an international perspective (preventive policies, developing countries). (HSCH).

  6. Environmental Concerns, Environmental Policy and Green Investment.

    Science.gov (United States)

    Gao, Xuexian; Zheng, Haidong

    2017-12-13

    Environmental regulators often use environmental policy to induce green investment by firms. However, if an environmental policy fails to exert a long-run effect on regulating the economic agents' behavior, it may be more reasonable to think of the firm as the leader in the game, since the investment in green technology is usually a strategic decision. In this paper, we consider a three-stage Stackelberg game to address the interaction between a profit-maximizing firm (Stackelberg leader) facing emission-dependent demand, and the environmental regulator (Stackelberg follower). The firm decides on the green technology level in the first stage of the game based on its understanding of the regulator's profits function, especially an environmental concern that is introduced as an exogenous variable. In the current research, we show that high levels of the regulator's environmental concerns do not necessarily lead to the choice of green technology by the firm, and green investment level depends on the combined effects of the market and operational factors for a given level of the regulator's environmental concerns. The result also shows that increasing environmental awareness amongst the consumers is an effective way to drive the firm's green investment.

  7. Regulated and unregulated emissions from highway heavy-duty diesel engines complying with U.S. Environmental Protection Agency 2007 emissions standards.

    Science.gov (United States)

    Khalek, Imad A; Bougher, Thomas L; Merritt, Patrick M; Zielinska, Barbara

    2011-04-01

    As part of the Advanced Collaborative Emissions Study (ACES), regulated and unregulated exhaust emissions from four different 2007 model year U.S. Environmental Protection Agency (EPA)-compliant heavy-duty highway diesel engines were measured on an engine dynamometer. The engines were equipped with exhaust high-efficiency catalyzed diesel particle filters (C-DPFs) that are actively regenerated or cleaned using the engine control module. Regulated emissions of carbon monoxide, nonmethane hydrocarbons, and particulate matter (PM) were on average 97, 89, and 86% lower than the 2007 EPA standard, respectively, and oxides of nitrogen (NOx) were on average 9% lower. Unregulated exhaust emissions of nitrogen dioxide (NO2) emissions were on, average 1.3 and 2.8 times higher than the NO, emissions reported in previous work using 1998- and 2004-technology engines, respectively. However, compared with other work performed on 1994- to 2004-technology engines, average emission reductions in the range of 71-99% were observed for a very comprehensive list of unregulated engine exhaust pollutants and air toxic contaminants that included metals and other elements, elemental carbon (EC), inorganic ions, and gas- and particle-phase volatile and semi-volatile organic carbon (OC) compounds. The low PM mass emitted from the 2007 technology ACES engines was composed mainly of sulfate (53%) and OC (30%), with a small fraction of EC (13%) and metals and other elements (4%). The fraction of EC is expected to remain small, regardless of engine operation, because of the presence of the high-efficiency C-DPF in the exhaust. This is different from typical PM composition of pre-2007 engines with EC in the range of 10-90%, depending on engine operation. Most of the particles emitted from the 2007 engines were mainly volatile nuclei mode in the sub-30-nm size range. An increase in volatile nanoparticles was observed during C-DPF active regeneration, during which the observed particle number was

  8. Regulated and unregulated emissions from modern 2010 emissions-compliant heavy-duty on-highway diesel engines.

    Science.gov (United States)

    Khalek, Imad A; Blanks, Matthew G; Merritt, Patrick M; Zielinska, Barbara

    2015-08-01

    The U.S. Environmental Protection Agency (EPA) established strict regulations for highway diesel engine exhaust emissions of particulate matter (PM) and nitrogen oxides (NOx) to aid in meeting the National Ambient Air Quality Standards. The emission standards were phased in with stringent standards for 2007 model year (MY) heavy-duty engines (HDEs), and even more stringent NOX standards for 2010 and later model years. The Health Effects Institute, in cooperation with the Coordinating Research Council, funded by government and the private sector, designed and conducted a research program, the Advanced Collaborative Emission Study (ACES), with multiple objectives, including detailed characterization of the emissions from both 2007- and 2010-compliant engines. The results from emission testing of 2007-compliant engines have already been reported in a previous publication. This paper reports the emissions testing results for three heavy-duty 2010-compliant engines intended for on-highway use. These engines were equipped with an exhaust diesel oxidation catalyst (DOC), high-efficiency catalyzed diesel particle filter (DPF), urea-based selective catalytic reduction catalyst (SCR), and ammonia slip catalyst (AMOX), and were fueled with ultra-low-sulfur diesel fuel (~6.5 ppm sulfur). Average regulated and unregulated emissions of more than 780 chemical species were characterized in engine exhaust under transient engine operation using the Federal Test Procedure cycle and a 16-hr duty cycle representing a wide dynamic range of real-world engine operation. The 2010 engines' regulated emissions of PM, NOX, nonmethane hydrocarbons, and carbon monoxide were all well below the EPA 2010 emission standards. Moreover, the unregulated emissions of polycyclic aromatic hydrocarbons (PAHs), nitroPAHs, hopanes and steranes, alcohols and organic acids, alkanes, carbonyls, dioxins and furans, inorganic ions, metals and elements, elemental carbon, and particle number were substantially (90

  9. Environmental law

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    This pocketbook contains major federal regulations on environmental protection. They serve to protect and cultivate mankind's natural foundations of life, to preserve the environment. The environmental law is devided as follows: Constitutional law on the environment, common administrative law on the environment, special administrative law on the environment including conservation of nature and preservation of rural amenities, protection of waters, waste management, protection against nuisances, nuclear energy and radiation protection, energy conservation, protection against dangerous substances, private law relating to the environment, criminal law relating to the environment. (HSCH) [de

  10. Environmental Survey preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    1988-04-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Sandia National Laboratories conducted August 17 through September 4, 1987. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with Sandia National Laboratories-Albuquerque (SNLA). The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at SNLA, and interviews with site personnel. 85 refs., 49 figs., 48 tabs.

  11. Regulation of acetyl-CoA synthetase transcription by the CrbS/R two-component system is conserved in genetically diverse environmental pathogens.

    Directory of Open Access Journals (Sweden)

    Kristin Jacob

    Full Text Available The CrbS/R two-component signal transduction system is a conserved regulatory mechanism through which specific Gram-negative bacteria control acetate flux into primary metabolic pathways. CrbS/R governs expression of acetyl-CoA synthase (acsA, an enzyme that converts acetate to acetyl-CoA, a metabolite at the nexus of the cell's most important energy-harvesting and biosynthetic reactions. During infection, bacteria can utilize this system to hijack host acetate metabolism and alter the course of colonization and pathogenesis. In toxigenic strains of Vibrio cholerae, CrbS/R-dependent expression of acsA is required for virulence in an arthropod model. Here, we investigate the function of the CrbS/R system in Pseudomonas aeruginosa, Pseudomonas entomophila, and non-toxigenic V. cholerae strains. We demonstrate that its role in acetate metabolism is conserved; this system regulates expression of the acsA gene and is required for growth on acetate as a sole carbon source. As a first step towards describing the mechanism of signaling through this pathway, we identify residues and domains that may be critical for phosphotransfer. We further demonstrate that although CrbS, the putative hybrid sensor kinase, carries both a histidine kinase domain and a receiver domain, the latter is not required for acsA transcription. In order to determine whether our findings are relevant to pathogenesis, we tested our strains in a Drosophila model of oral infection previously employed for the study of acetate-dependent virulence by V. cholerae. We show that non-toxigenic V. cholerae strains lacking CrbS or CrbR are significantly less virulent than are wild-type strains, while P. aeruginosa and P. entomophila lacking CrbS or CrbR are fully pathogenic. Together, the data suggest that the CrbS/R system plays a central role in acetate metabolism in V. cholerae, P. aeruginosa, and P. entomophila. However, each microbe's unique environmental adaptations and pathogenesis

  12. Safety and environmental aspects of zinc--chlorine hydrate batteries for electric-vehicle applications

    Energy Technology Data Exchange (ETDEWEB)

    Kodali, S.; Henriksen, G.L.; Whittlesey, C.C.; Warde, C.J.; Carr, P.; Symons, P.C.

    1978-03-01

    Public acceptance of high-performance cost-effective zinc--chlorine hydrate batteries for the random-use electric-vehicle application will require meeting stringent safety and environmental requirements. These requirements revolve mainly around the question of accidental release and spread of toxic amounts of chlorine gas, the only potential hazard in this battery system. Available information in the areas of physiological effects, environmental impact, and governmental regulation of chlorine were reviewed. The design, operation, and safety features of a first commercial electric-vehicle battery were conceived and analyzed from the chlorine release aspect. Two types of accident scenarios were analyzed in terms of chlorine release rates, atmospheric dispersion, health hazard, and possible clean-up operations. The worst-case scenario, a quite improbable accident, involves the spillage of chlorine hydrate onto the ground, while the other scenario, a more probable accident, involves the release of chlorine gas from a ruptured battery case. Heat-transfer and chlorine-dispersion models, developed to analyze these scenarios, establish a firm basis for a comprehenive and factual position statement on this topic. The results of this preliminary study suggest that electric vehicles powered by appropriately designed zinc--chlorine hydrate batteries will pose negligible health or environmental hazards on the nation's streets and highways. 8 figures, 14 tables.

  13. W. European refiners face tough environmental rules

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    This paper reports that western Europe's refiners are beginning to grapple with the kind of fundamental changes and huge outlays related to stringent new environmental standards their U.S. counterparts are encountering. Just as the 1990 amendments to the Clean Air Act (CAAA) is transforming the shape of U.S refining and imposing staggering costs on refiners there, new directives proposed by the European Community Commission threaten the same for western European refiners. Given the current state of the industry in Europe, industry officials warn, refiners there might not be able to fund those massive environmental outlays

  14. Corporate environmentalism and sustainable development

    International Nuclear Information System (INIS)

    Aslam, A.I.

    2005-01-01

    For generations environmental degradation was considered as a normal course and by-product of business activity but this has gradually changed during the last thirty years as environment has gradually move up on the international agenda forcing corporations to take the environment seriously. The last thirty years witnessed environmental laws becoming stringent and enforcement more rigorous, transformation in business models and operating procedures for the protection of the environment, as well as a gradual increase in influence of environmentalists and environmental pressure groups in decision making processes. The paper describes how businesses during the last 30 years changed their operating strategies from emphasis on pure financials to triple bottom line for addressing sustainability issues and in doing so positioned their brands and products as environmentally friendly. The paper explores major drivers and factors like environmental protection mechanism and regimes, pressure from stake holders and corporate social responsibility behind this change. It then establishes a link between regulatory requirements and current practices on environmental disclosures especially in financial statements and environmental reports. The paper also highlights shortcomings in business models as well as accounting standards and explains how those shortcomings have contributed to environmental degradation. (author)

  15. Policy and Strategies for Environmental Remediation

    International Nuclear Information System (INIS)

    2015-01-01

    In the environmental remediation of a given site, concerned and interested parties have diverse and often conflicting interests with regard to remediation goals, the time frames involved, reuse of the site, the efforts necessary and cost allocation. An environmental remediation policy is essential for establishing the core values on which remediation is to be based. It incorporates a set of principles to ensure the safe and efficient management of remediation situations. Policy is mainly established by the national government and may become codified in the national legislative system. An environmental remediation strategy sets out the means for satisfying the principles and requirements of the national policy. It is normally established by the relevant remediation implementer or by the government in the case of legacy sites. Thus, the national policy may be elaborated in several different strategies. To ensure the safe, technically optimal and cost effective management of remediation situations, countries are advised to formulate an appropriate policy and strategies. Situations involving remediation include remediation of legacy sites (sites where past activities were not stringently regulated or adequately supervised), remediation after emergencies (nuclear and radiological) and remediation after planned ongoing operation and decommissioning. The environmental policy involves the principles of justification, optimization of protection, protection of future generations and the environment, efficiency in the use of resources, and transparent interaction with stakeholders. A typical policy will also take into account the national legal framework and institutional structure and applicable international conventions while providing for the allocation of responsibilities and resources, in addition to safety and security objectives and public information and participation in the decision making process. The strategy reflects and elaborates the goals and requirements set

  16. Industrial pollution of the Moselle River: the birth, development and management of an environmental problem, 1850-2000

    International Nuclear Information System (INIS)

    Garcier, J.R.

    2005-12-01

    In the 1850's, the water quality of surface waters in the Moselle river drainage basin began to suffer from the development of heavy industrial activities (coal and iron ore mining, steel and soda making). Industrial development also fuelled a demographic impetus that proved detrimental to the quality of surface waters. This study uses archival sources to analyse the ineffectiveness of the policies that were launched to regulate pollution. In a region traumatized by the Prussian annexation of a quarter of its surface (1870), industrial production enjoyed a symbolic protection that allowed water pollution to go unabated. The fuzzy status of pollution in law contributed to the immunity of industrialists. From the 1950's on, fear that the region might experience severe water shortages due to the growth of water consumption by industries and cities alike enabled more stringent policies to be devised. They still had to take into account the interests of the heavy industry and their effectiveness is questionable. Hydrological planning was based upon a functionalist vision of water resources that did not take environmental issues into account. The situation changed in the 1970's and 1980's, when European integration and the Sandoz catastrophe in the Rhine (November 1986) tipped the scale in favour of more vigorous environmental policies. This study develops the concepts of a 'regional system' and of the 'mode of construction' of an environmental problem. These prove to be valuable theoretical elements to ground environmental geography studies. (author)

  17. Environmental protection

    International Nuclear Information System (INIS)

    Klinda, J.; Lieskovska, Z.

    1998-01-01

    In this chapter environmental protection in the Slovak Republic in 1997 are reviewed. The economics of environmental protection, state budget, Slovak state environmental fund, economic instruments, environmental laws, environmental impact assessment, environmental management systems, and environmental education are presented

  18. Hanford Site Environmental Report for Calendar Year 2000

    Energy Technology Data Exchange (ETDEWEB)

    Poston, Ted M.; Hanf, Robert W.; Dirkes, Roger L.; Morasch, Launa F.

    2001-09-25

    This Hanford Site environmental report is prepared annually to summarize environmental data and information, to describe environmental management performance, to demonstrate the status of compliance with environmental regulations, and to highlight major environmental programs and efforts.

  19. Hanford Site Environmental Report for Calendar Year 1999

    Energy Technology Data Exchange (ETDEWEB)

    Poston, Ted M.; Hanf, Robert W.; Dirkes, Roger L.

    2000-09-28

    The Hanford Site environmental report is prepared annually to summarize environmental data and information, to describe environmental management performance, to demonstrate the status of compliance with environmental regulations, and to highlight major environmental programs and efforts.

  20. Environmental protection implementation plan

    International Nuclear Information System (INIS)

    Holland, R.C.

    1998-03-01

    This Environmental Protection Implementation Plan is intended to ensure that the environmental program objectives of Department of Energy Order 5400.1 are achieved at SNL/California. This document states SNL/California's commitment to conduct its operations in an environmentally safe and responsible manner. The Environmental Protection Implementation Plan helps management and staff comply with applicable environmental responsibilities. SNL is committed to operating in full compliance with the letter and spirit of applicable environmental laws, regulations, and standards. Furthermore, SNL/California strives to go beyond compliance with legal requirements by making every effort practical to reduce impacts to the environment to levels as low as reasonably achievable

  1. Environmental impact statements

    International Nuclear Information System (INIS)

    Stewing, C.

    1986-01-01

    The adoption of US-type environmental impact statements is considered to be approaching. Environmental impact statements are defined as comprehensive analyses of the future effects of measures on environmental conditions with the aim of avoiding ecological disadvantages. The recommendation ratified by the European Communities on June 27, 1985 requires the environmental impact statement to be implemented as a mandatory procedure. The implementation is difficult to realize. Particular problems consist in the alignment of the environmental impact statement with existing administrative procedures and in the operationable formulation of the aims and results of the statement. Paragraph 72 of the administrative procedures law (VwVfG) shows that planning procedures and environmental impact statement are to be treated as two parallel regulations. The structural order of environmental impact statements must therefore be integrated into the regulations of planning procedures. (orig./HP) [de

  2. AtLa1 protein initiates IRES-dependent translation of WUSCHEL mRNA and regulates the stem cell homeostasis of Arabidopsis in response to environmental hazards.

    Science.gov (United States)

    Cui, Yuchao; Rao, Shaofei; Chang, Beibei; Wang, Xiaoshuang; Zhang, Kaidian; Hou, Xueliang; Zhu, Xueyi; Wu, Haijun; Tian, Zhaoxia; Zhao, Zhong; Yang, Chengwei; Huang, Tao

    2015-10-01

    Plant stem cells are hypersensitive to environmental hazards throughout their life cycle, but the mechanism by which plants safeguard stem cell homeostasis in response to environmental hazards is largely unknown. The homeodomain transcription factor WUSCHEL (WUS) protein maintains the stem cell pool in the shoot apical meristem of Arabidopsis. Here, we demonstrate that the translation of WUS mRNA is directed by an internal ribosomal entry site (IRES) located in the 5'-untranslated region. The AtLa1 protein, an RNA-binding factor, binds to the 5'-untranslated region and initiates the IRES-dependent translation of WUS mRNA. Knockdown of AtLa1 expression represses the WUS IRES-dependent translation and leads to the arrest of growth and development. The AtLa1 protein is mainly located in the nucleoplasm. However, environmental hazards promote the nuclear-to-cytoplasmic translocation of the AtLa1 protein, which further enhances the IRES-dependent translation of WUS mRNA. Genetic evidence indicates that the WUS protein increases the tolerance of the shoot apical meristem to environmental hazards. Based on these results, we conclude that the stem cell niche in Arabidopsis copes with environmental hazards by enhancing the IRES-dependent translation of WUS mRNA under the control of the AtLa1 protein. © 2015 John Wiley & Sons Ltd.

  3. Multinationals and international environmental policy

    International Nuclear Information System (INIS)

    Dam, L.; Scholtens, B.

    2009-01-01

    Multinationals with relatively poor environmental policy establish themselves in countries with weak environmental regulation. These activities are not undertaken in the poorest or most corrupt countries though. The question arises if multinationals with relatively developed environmental behavior settle less or more often in countries with environmental legislation. [mk] [nl

  4. Genome sequencing of environmental Escherichia coli expands understanding of the ecology and speciation of the model bacterial species.

    Science.gov (United States)

    Luo, Chengwei; Walk, Seth T; Gordon, David M; Feldgarden, Michael; Tiedje, James M; Konstantinidis, Konstantinos T

    2011-04-26

    Defining bacterial species remains a challenging problem even for the model bacterium Escherichia coli and has major practical consequences for reliable diagnosis of infectious disease agents and regulations for transport and possession of organisms of economic importance. E. coli traditionally is thought to live within the gastrointestinal tract of humans and other warm-blooded animals and not to survive for extended periods outside its host; this understanding is the basis for its widespread use as a fecal contamination indicator. Here, we report the genome sequences of nine environmentally adapted strains that are phenotypically and taxonomically indistinguishable from typical E. coli (commensal or pathogenic). We find, however, that the commensal genomes encode for more functions that are important for fitness in the human gut, do not exchange genetic material with their environmental counterparts, and hence do not evolve according to the recently proposed fragmented speciation model. These findings are consistent with a more stringent and ecologic definition for bacterial species than the current definition and provide means to start replacing traditional approaches of defining distinctive phenotypes for new species with omics-based procedures. They also have important implications for reliable diagnosis and regulation of pathogenic E. coli and for the coliform cell-counting test.

  5. Program of environmental radiological monitoring

    International Nuclear Information System (INIS)

    2005-11-01

    This Regulation refers to the requirement of the Regulation CNEN-NN.3.01, 'Basic Act of Radiological Protection', as expressed in the section 5.14, related to the Program of Environmental Radiological Monitoring (PMRA)

  6. Evaluating Environmental Governance along Cross-Border Electricity Supply Chains with Policy-Informed Life Cycle Assessment: The California-Mexico Energy Exchange.

    Science.gov (United States)

    Bolorinos, Jose; Ajami, Newsha K; Muñoz Meléndez, Gabriela; Jackson, Robert B

    2018-04-12

    This paper presents a "policy-informed" life cycle assessment of a cross-border electricity supply chain that links the impact of each unit process to its governing policy framework. An assessment method is developed and applied to the California-Mexico energy exchange as a unique case study. CO 2 -equivalent emissions impacts, water withdrawals, and air quality impacts associated with California's imports of electricity from Mexican combined-cycle facilities fueled by natural gas from the U.S. Southwest are estimated, and U.S. and Mexican state and federal environmental regulations are examined to assess well-to-wire consistency of energy policies. Results indicate most of the water withdrawn per kWh exported to California occurs in Baja California, most of the air quality impacts accrue in the U.S. Southwest, and emissions of CO 2 -equivalents are more evenly divided between the two regions. California energy policy design addresses generation-phase CO 2 emissions, but not upstream CO 2 -eq emissions of methane during the fuel cycle. Water and air quality impacts are not regulated consistently due to varying U.S. state policies and a lack of stringent federal regulation of unconventional gas development. Considering local impacts and the regulatory context where they occur provides essential qualitative information for functional-unit-based measures of life cycle impact and is necessary for a more complete environmental impact assessment.

  7. The Regulation of Major Risks in Relation to Large Nuclear Installations in France

    International Nuclear Information System (INIS)

    Phan Van, L.

    1991-01-01

    Recently, major risk prevention has generated legislative and regulatory texts in French law, particularly regarding nuclear installations. This article reviews the context and analyses the scope of the new regulations. They require the nuclear operator to take preventive measures, namely more stringent obligations from the safety viewpoint to inform the public. These include risk assessments and preparing emergency plans in case if accidents. (NEA)

  8. ENVIRONMENTAL CONCERN AND ENVIRONMENTALLY ...

    African Journals Online (AJOL)

    In this study, environmental concern has been conceptualised as the manifestation of attitudes that are directed at behavioural intentions of active personal involvement in caring about environmental matters. Based on a critique of theoretical approaches towards understanding the formation of environmental attitudes, ...

  9. BIOSENSORS FOR ENVIRONMENTAL APPLICATIONS

    Science.gov (United States)

    A review, with 19 references, is given on challenges and possible opportunities for the development of biosensors for environmental monitoring applications. The high cost and slow turnaround times typically associated with the measurement of regulated pollutants clearly indicates...

  10. Environmental impact assessment modern dressed? To the amendment of the EIA act and other acts and regulations; Umweltvertraeglichkeitspruefung im modernen Gewand? Zur Aenderung des UVP-Gesetzes und zahlreicher weiterer Gesetze und Verordnungen

    Energy Technology Data Exchange (ETDEWEB)

    Feldmann, Ulrike

    2017-03-15

    On 22 December 2016, the Federal Ministry for the Environment (BMUB) presented the ''Draft Act for the Modernization of the Act on the Environmental Impact Assessment'' within the framework of the association consultation, as well as the ''Draft first Ordinance Amending the Ordinance on the Approval Procedure - 9. BImSchV''. The EIA Modernization Act as well as the Atomic Act Procedure Regulation and the Federal Mining Act should be revised by terms of an omnibus act. The association consultation was held on 18 January 2017.

  11. Pale and dark reddish melanic tawny owls differentially regulate the level of blood circulating POMC prohormone in relation to environmental conditions

    NARCIS (Netherlands)

    Roulin, Alexandre; Emaresi, Guillaume; Bize, Pierre; Gasparini, Julien; Piault, Romain; Ducrest, Anne-Lyse

    Knowledge of the hormonal pathway controlling genotype-specific norms of reaction would shed light on the ecological factors to which each genotype is adapted. Environmentally mediated changes in the sign and magnitude of covariations between heritable melanin-based colouration and fitness

  12. The Swedish radiological environmental protection regulations applied in a review of a license application for a geological repository for spent nuclear fuel.

    Science.gov (United States)

    Andersson, Pål; Stark, Karolina; Xu, Shulan; Nordén, Maria; Dverstorp, Björn

    2017-11-01

    For the first time, a system for specific consideration of radiological environmental protection has been applied in a major license application in Sweden. In 2011 the Swedish Nuclear Fuel & Waste Management Co. (SKB) submitted a license application for construction of a geological repository for spent nuclear fuel at the Forsmark site. The license application is supported by a post-closure safety assessment, which in accordance with regulatory requirements includes an assessment of environmental consequences. SKB's environmental risk assessment uses the freely available ERICA Tool. Environmental media activity concentrations needed as input to the tool are calculated by means of complex biosphere modelling based on site-specific information gathered from site investigations, as well as from supporting modelling studies and projections of future biosphere conditions in response to climate change and land rise due to glacial rebound. SKB's application is currently being reviewed by the Swedish Radiation Safety Authority (SSM). In addition to a traditional document review with an aim to determine whether SKB's models are relevant, correctly implemented and adequately parametrized, SSM has performed independent modelling in order to gain confidence in the robustness of SKB's assessment. Thus, SSM has used alternative stylized reference biosphere models to calculate environmental activity concentrations for use in subsequent exposure calculations. Secondly, an alternative dose model (RESRAD-BIOTA) is used to calculate doses to biota that are compared with SKB's calculations with the ERICA tool. SSM's experience from this review is that existing tools for environmental dose assessment are possible to use in order to show compliance with Swedish legislation. However, care is needed when site representative species are assessed with the aim to contrast them to generic reference organism. The alternative modelling of environmental concentrations resulted in much lower

  13. Physical activity, but not environmental complexity, facilitates HPA axis response habituation to repeated audiogenic stress despite neurotrophin mRNA regulation in both conditions.

    Science.gov (United States)

    Nyhuis, Tara J; Masini, Cher V; Sasse, Sarah K; Day, Heidi E W; Campeau, Serge

    2010-11-29

    Stress exacerbates several physical and psychological disorders. Voluntary exercise can reduce susceptibility to many of these stress-associated disorders. In rodents, voluntary exercise can reduce hypothalamic-pituitary-adrenocortical (HPA) axis activity in response to various stressors as well as upregulate several brain neurotrophins. An important issue regarding voluntary exercise is whether its effect on the reduction of HPA axis activation in response to stress is due to the physical activity itself or simply the enhanced environmental complexity provided by the running wheels. The present study compared the effects of physical activity and environmental complexity (that did not increase physical activity) on HPA axis habituation to repeated stress and modulation of brain neurotrophin mRNA expression. For six weeks, male rats were given free access to running wheels (exercise group), given 4 objects that were repeatedly exchanged (increased environmental complexity group), or housed in standard cages. On week 7, animals were exposed to 11 consecutive daily 30-min sessions of 98-dBA noise. Plasma corticosterone and adrenocorticotropic hormone were measured from blood collected directly after noise exposures. Tissue, including brains, thymi, and adrenal glands was collected on Day 11. Although rats in both the exercise and enhanced environmental complexity groups expressed higher levels of BDNF and NGF mRNA in several brain regions, only exercise animals showed quicker glucocorticoid habituation to repeated audiogenic stress. These results suggest that voluntary exercise, independent from other environmental manipulations, accounts for the reduction in susceptibility to stress. Copyright © 2010 Elsevier B.V. All rights reserved.

  14. Environmental Regulation of Plant Gene Expression: An Rt-qPCR Laboratory Project for an Upper-Level Undergraduate Biochemistry or Molecular Biology Course

    Science.gov (United States)

    Eickelberg, Garrett J.; Fisher, Alison J.

    2013-01-01

    We present a novel laboratory project employing "real-time" RT-qPCR to measure the effect of environment on the expression of the "FLOWERING LOCUS C" gene, a key regulator of floral timing in "Arabidopsis thaliana" plants. The project requires four 3-hr laboratory sessions and is aimed at upper-level undergraduate…

  15. Environmental priorities in Komi

    International Nuclear Information System (INIS)

    Borg, D.

    1994-01-01

    The big Russian republic Komi situated in the Ural Mountain region, suffers tremendous pollution problems despite its scarce population members. The Danish company N and R Consult has prepared an ''Ecological environment report'' commissioned by the Komi government. The N and R Consult tries to map the most important pollution areas: the Workuta coal mining region and coal-fueled power plants, petroleum refinery at Ukhta, oil wells at Usinsk, natural gas industry at Sosnogorsk. All these industrial enterprises have practically no filters for their noxious gas emissions, the Pechora river is massively polluted by industrial waste water and occasional oil spills from leaking pipelines. Mountains of industrial slags add to ground water pollution. Concentrations of petroleum products, phenols, heavy metals and pesticides in river water are periodically totally unacceptable. The government of the Komi republic needs assistance in its environmental endeavours, the present pollution limit norms being as stringent as in the West Europe. Waste processing plants are planned. Standard procedures for Arctic environment protection in oil- and mineral recovelry processes are being prepared in a coordinated master plan. Special companies are established by the N and R Consult and the Komi State Oil Company in order to solve the problems of the environmental policy. (EG)

  16. 10 CFR 51.45 - Environmental report.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Environmental report. 51.45 Section 51.45 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy Act-Regulations Implementing Section 102(2) Environmental...

  17. International Symposium on Uranium Raw Material for the Nuclear Fuel Cycle: Exploration, Mining, Production, Supply and Demand, Economics and Environmental Issues. Book of Abstracts

    International Nuclear Information System (INIS)

    2014-01-01

    The long term sustainability of nuclear power will depend on, among several factors, an adequate supply of uranium resources that can be delivered to the marketplace at competitive prices. New exploration technologies and a better understanding of the genesis of uranium ores will be required to discover often deep-seated and increasingly hard to find uranium deposits. Exploration, mining and milling technologies should be environmentally benign, and site decommissioning plans should meet the requirements of increasingly stringent environmental regulations and societal expectations. The purpose of this symposium is to analyse uranium supply–demand scenarios and to present and discuss new developments in uranium geology, exploration, mining and processing, as well as in environmental requirements for uranium operations and site decommissioning. The presentations and discussions at URAM-2014 will: - Lead to a better understanding of the adequacy of uranium sources (both primary and secondary) to meet future demand; - Provide information on geological models, new exploration concepts, knowledge and technologies that will potentially lead to the discovery and development of new uranium resources; - Describe new production technologies that have the potential to more efficiently and sustainably develop new uranium resources; and - Document the environmental compatibility of uranium production and the overall effectiveness of progressive final decommissioning and, where required, remediation of production facilities.

  18. 2014 Site Environmental Report

    Energy Technology Data Exchange (ETDEWEB)

    Paquette, Douglas [Brookhaven National Lab. (BNL), Upton, NY (United States); Remien, Jason [Brookhaven National Lab. (BNL), Upton, NY (United States); Foley, Brian [Brookhaven National Lab. (BNL), Upton, NY (United States); Burke, John [Brookhaven National Lab. (BNL), Upton, NY (United States); Dorsch, William [Brookhaven National Lab. (BNL), Upton, NY (United States); Ratel, Karen [Brookhaven National Lab. (BNL), Upton, NY (United States); Howe, Robert [Brookhaven National Lab. (BNL), Upton, NY (United States); Welty, Tim [Brookhaven National Lab. (BNL), Upton, NY (United States); Williams, Jeffrey [Brookhaven National Lab. (BNL), Upton, NY (United States); Pohlpt, Peter [Brookhaven National Lab. (BNL), Upton, NY (United States); Lagattolla, Richard [Brookhaven National Lab. (BNL), Upton, NY (United States); Metz, Robert [Brookhaven National Lab. (BNL), Upton, NY (United States); Milligan, James [Brookhaven National Lab. (BNL), Upton, NY (United States); Lettieri, Lawrence [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-10-01

    BNL prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1B, Environment, Safety and Health Reporting. The report is written to inform the public, regulators, employees, and other stakeholders of the Laboratory’s environmental performance during the calendar year in review.

  19. Maintaining an Environmental Balance

    Science.gov (United States)

    Environmental Science and Technology, 1976

    1976-01-01

    A recent conference of the National Environmental Development Association focused on the concepts of environment, energy and economy and underscored the necessity for balancing the critical needs embodied in these issues. Topics discussed included: nuclear energy and wastes, water pollution control, federal regulations, environmental technology…

  20. Decree of the President of the Council of Ministers, 10 August 1988, No. 377, providing for the regulation of environmental compatibility in accordance with Section 6 of Act No. 349 of 8 July 1986 concerning the Ministry of the Environment and regulations in the field of environmental damage

    International Nuclear Information System (INIS)

    1988-01-01

    This Decree concerns the compatibility of industrial installations and equipment - both public and private - with environmental protection. The Decree entered into force on the day following its publication. It specifies the conditions for performing environmental impact assessments and the information to be provided at the planning stage of the installations involved. Those include nuclear power plants and other reactors. The Decree further provides that facilities for the final storage and disposal of radioactive waste also require an environmental impact assessment. (NEA) [fr

  1. The community regulation for environmental management and audit: an opportunity for firms. Some Enea promotion actions; Il regolamento comunitario di ecogestione e audit: un'opportunita' per le imprese. Alcune azioni promozionali ENEA

    Energy Technology Data Exchange (ETDEWEB)

    Andriola, L.; Brunetti, N.; Caropreso, G.; Luciani, R.; Merelli, A. [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dipt. Ambiente

    1999-07-01

    EMAS (Environmental Management and Audit Scheme), introduced by the 1836/93 Community regulation, is one of the tools activated by the European Union in the field of firm-environment interactions, to overcome the old Command and Control logic by means of the new Moral Suasion one. EMAS has a voluntary character: it intends to replace conflicting relations between control authority and firm with relations centred on a dialogue and action agreed upon by the parties, on the basis of impartial and reliable information. The report illustrates the procedure for applying this regulation, EMAS advantages for firms, its implementation in Italy and the most important pilot actions carried out by ENEA. [Italian] L'EMAS (Environmental Management and Audit Scheme), introdotto con il Regolamento comunitario 1836/93, rappresenta uno degli strumenti che l'Unione europea ha attivato nel campo delle interazioni impresa-ambiente, per superare la vecchia logica del Command and Control (imponi e controlla) mediante la nuova logica della Moral Suasion (persuasione morale). Lo strumento EMAS, che ha carattere di volontarieta', intende sostituire un rapporto di tipo conflittuale fra autorita' di controllo ed impresa con un rapporto centrato su un dialogo ed un'azione concertata tra le parti, sulle basi di un'informativa obiettiva ed affidabile. Il rapporto illustra il percorso per l'applicazione del regolamento, i vantaggi di EMAS per le aziende, il suo stato di attuazione in Italia e le principali azioni pilota svolte da ENEA.

  2. Environmental regulation of plant gene expression: an RT-qPCR laboratory project for an upper-level undergraduate biochemistry or molecular biology course.

    Science.gov (United States)

    Eickelberg, Garrett J; Fisher, Alison J

    2013-01-01

    We present a novel laboratory project employing "real-time" RT-qPCR to measure the effect of environment on the expression of the FLOWERING LOCUS C gene, a key regulator of floral timing in Arabidopsis thaliana plants. The project requires four 3-hr laboratory sessions and is aimed at upper-level undergraduate students in biochemistry or molecular biology courses. The project provides students with hands-on experience with RT-qPCR, the current "gold standard" for gene expression analysis, including detailed data analysis using the common 2-ΔΔCT method. Moreover, it provides a convenient starting point for many inquiry-driven projects addressing diverse questions concerning ecological biochemistry, naturally occurring genetic variation, developmental biology, and the regulation of gene expression in nature. Copyright © 2013 Wiley Periodicals, Inc.

  3. Environmental Productivity in China

    OpenAIRE

    Shunsuke Managi; Shinji Kaneko

    2004-01-01

    Environmental problems are threatening China's sustainable future. China began implementation of several environmental policies for the late 1970s and stringency of the regulations is increasing over time. We utilize a province-level economy wide data set over 1987-2001 to measure various components of productivity within a joint production model, which considers both market and environmental outputs. While productivity level of a joint production is relatively constant over time, environment...

  4. Transversalidad de conceptos de educación ambiental para un desarrollo sostenible presentes en la legislación argentina Environmental education as a crosscutting issue for sustainable developement concepts included in Argentine regulations

    Directory of Open Access Journals (Sweden)

    Lidia Giuffré

    2007-07-01

    instituciones de educación superior. Se asegura el derecho a la información, todo habitante podrá obtener de las autoridades la información ambiental que administren y que no se encuentre contemplada legalmente como reservada. Los aspectos más importantes acerca de la educación ambiental y el desarrollo sostenible son ejes transversales de leyes de distinta jurisdicción, pero deberá bregarse por el cumplimiento y control de dichos principios, debido a las características con las que se percibe al derecho ambiental, de baja eficacia y eficiencia.Population environmental education must be conveyed in all educational levels, in order to contribute to a deep knowledge of environmental protection laws. These include contents about environmental education, but with scarce diffusion and low adhesion. If environmental education could force a detailed knowledge about regulations, its application could be demanded by community actions. Moreover, environmental education is considered in regulations as a fundamental tool for sustainable development. There is a profuse legislation in Argentina, with more than 3,000 legal instruments of different hierarchical order and jurisdictional level. Three argentine laws were studied and compared: Environmental General Law (national: Law 25,675; La Pampa Environmental Law (province order: Law 1,914; and Environmental Education Law of Buenos Aires (city order: Law 1,687. These laws regulate the incorporation of environmental education in formal system (public and private schools and institutions, for all levels: initial, primary, secondary and university studies, non formal system (extra-curricular activities and/or extension inside the institutions, and non formal education (by means of massive instruments of communication and information. Environmental education is considered as the basic tool to generate values, behavior and attitudes according to a balanced environment, tending to the preservation of natural resources and their sustainable

  5. Building Transdisciplinary Environmental Studies

    DEFF Research Database (Denmark)

    Holm, Jesper

    We will in this paper approach the challenge of building integrated environmental studies by presenting a crude frame of analysis which take into account both the physical aspects and the social-discursive articulations of environmental problems. This framework partly mirrors the approach of our...... department (Dept. of Environment, Technology and Social Studies, Roskilde University), and has originally in another version been presented in the book “Miljøregulering - tværvidenskabelige studier (Environmental Regulation. Interdisciplinary Studies)” (Holm, Kjærgård & Pedersen eds. 1997, in Danish) written...

  6. The physiology of ex vitro pineapple (Ananas comosus L. Merr. var MD-2) as CAM or C3 is regulated by the environmental conditions: proteomic and transcriptomic profiles.

    Science.gov (United States)

    Aragón, C; Pascual, P; González, J; Escalona, M; Carvalho, L; Amancio, S

    2013-11-01

    Proteomic and transcriptomic profiles of key enzymes were monitored in pineapple plants propagated under C3 and CAM-inducing metabolisms to obtain insight into the CAM-facultative metabolism and the relationship of CAM plants with oxidative stress. Pineapple is one of the most important tropical crops worldwide. The use of temporary immersion bioreactors for the first stages of pineapple propagation enables precise control of plant growth, increases the rate of plant multiplication, decreases space, energy and labor requirements for pineapple plants in commercial micropropagation. Once the plantlets are ready to be taken from the reactors, they are carefully acclimatized to natural environmental conditions, and a facultative C3/CAM metabolism in the first 2 months of growth is the characteristic of pineapple plants, depending on environmental conditions. We subjected two sets of micropropagated pineapple plants to C3 and CAM-inducing environmental conditions, determined by light intensity/relative humidity (respectively 40 μmol m−2 s−1/85 % and 260 μmol m−2 s−1/50 %). Leaves of pineapple plants grown under CAM-inducing conditions showed higher leaf thickness and more developed cuticles and hypodermic tissue. Proteomic profiles of several proteins, isoenzyme patterns and transcriptomic profiles were also measured. Five major spots were isolated and identified, two of them for the first time in Ananas comosus (OEE 1; OEE 2) and the other three corresponding to small fragments of the large subunit of Rubisco (LSU). PEPC and PEPCK were also detected by immunobloting of 2DE at the end of both ex vitro treatments (C3/CAM) during the dark period. Isoenzymes of SOD and CAT were identified by electrophoresis and the transcript levels of OEE 1 and CAT were associated with CAM metabolism in pineapple plants.

  7. Business self-regulation as a tool for environmental management in the European Union Auto-regulação empresarial com instrumento de gestão ambiental na União Européia

    Directory of Open Access Journals (Sweden)

    Viviane Passos Gomes

    2009-12-01

    Full Text Available The responsibility to preserve the environment can no longer be seen simply as an obligation of the State. It is also the responsibility of the business sector, mainly for being a major cause of environmental degradation, to seek appropriate solutions to internalize the social and environmental costs generated by their production. In recent years there has been a growing adherence of businesses to voluntary instruments of environmental management within the European Union, especially with the adoption of systems such as EMAS and ISO 14000, which combine efforts to regulate even matters that are not included in the current environmental legislation. A responsabilidade de preservar o meio ambiente não pode mais ser encarada como uma obrigação tão somente do Estado, cabe também ao setor empresarial, incluso por ser uma dos maiores causadores da degradação ambiental, buscar soluções adequadas para internalizar o custo sócio-ambiental gerado por sua produção. Nos últimos anos vem crescendo a adesão de empresas aos instrumentos voluntários de gestão ambiental no âmbito da União Européia, principalmente com adoção de sistemas como o EMAS e a ISO 14000, que combinam esforços no sentido regular inclusive questões que não estão normatizadas na legislação ambiental vigente.

  8. Hanford Site Environmental Report for Calendar Year 2003

    Energy Technology Data Exchange (ETDEWEB)

    Poston, Ted M.; Hanf, Robert W.; Dirkes, Roger L.; Morasch, Launa F.

    2004-09-01

    This report is published each year by DOE to summarize environmental data and information, describe environmental management performance, demonstrate the status of compliance with environmental regulations, and highlight major environmental programs and efforts.

  9. Environmental Compliance Management System

    International Nuclear Information System (INIS)

    Brownson, L.W.; Krsul, T.; Peralta, R.A.; Knudson, D.A.; Rosignolo, C.L.

    1992-01-01

    Argonne National Laboratory (ANL) is developing the Environmental Compliance Management System (ECMS) as a comprehensive, cost-effective tool to ensure (1) that the Laboratory complies with all applicable federal and state environmental laws and regulations, (2) that environmental issues and concerns are recognized and considered in the early phases of projects; and (3) that Laboratory personnel conduct Laboratory operations in the most environmentally acceptable manner. The ECMS is an expert computer system which is designed to allow project engineers to perform an environmental evaluation of their projects. The system includes a Master Program which collects basic project information, provide utility functions, and access the environmental expert modules, environmental expert system modules for each federal and state environmental law which allows the user to obtain specific information on how an individual law may affect his project; and site-specific databases which contain information necessary for effective management of the site under environmental regulations. The ECMS will have the capability to complete and print many of the necessary environmental forms required by federal and state agencies, including the Department of Energy

  10. Safety assessment and environmental impact assessment: Application to regulation of nuclear and radiation safety, with special consideration to Lepse related operations

    International Nuclear Information System (INIS)

    Makarov, V.G.; Smith, G.M.; Stone, D.M.

    2000-11-01

    This report discusses the links between safety assessment and environmental impact assessment as applied to operations for unloading of spent nuclear fuel from the Lepse storage vessel. Regulatory responsibilities and regulatory requirements in these areas are under discussion and development in the Russian Federation and in other countries. The authors provide a briefing, based on inputs from Russian and western organisations, of their understanding of the situation at the time the work was done. They also make a variety of suggestions according to their perspectives. These suggestions should be relevant to the Lepse situation and to some other nuclear activities, bur do not represent the position of any particular organisation. Accordingly, this report is published by the SSI with the intention to promote discussion and interaction among relevant authorities

  11. Safety assessment and environmental impact assessment: Application to regulation of nuclear and radiation safety, with special consideration to Lepse related operations

    Energy Technology Data Exchange (ETDEWEB)

    Makarov, V.G. [Gosatomnadzor (Russian Federation); Smith, G.M.; Stone, D.M. [QuantiSci Ltd., Henley-on-Thames (United Kingdom)

    2000-11-01

    This report discusses the links between safety assessment and environmental impact assessment as applied to operations for unloading of spent nuclear fuel from the Lepse storage vessel. Regulatory responsibilities and regulatory requirements in these areas are under discussion and development in the Russian Federation and in other countries. The authors provide a briefing, based on inputs from Russian and western organisations, of their understanding of the situation at the time the work was done. They also make a variety of suggestions according to their perspectives. These suggestions should be relevant to the Lepse situation and to some other nuclear activities, bur do not represent the position of any particular organisation. Accordingly, this report is published by the SSI with the intention to promote discussion and interaction among relevant authorities.

  12. 2006 SITE ENVIRONMENTAL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    BROOKHAVEN NATIONAL LABORATORY; RATEL,K.

    2007-10-01

    Each year, Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of BNL's environmental performance during the calendar year in review. The SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and compliance, restoration, and surveillance monitoring program performance. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception in 1947. The report is available in print and as a downloadable file on the BNL web page at http://www.bnl.gov/ewms/ser/. A summary of the SER is also prepared each year to provide a general overview of the report, and is distributed with a CD of the full report.

  13. 2009 Site Environmental Report

    Energy Technology Data Exchange (ETDEWEB)

    Ratel, K.M.; Brookhaven National Laboratory

    2010-09-30

    Each year, Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of BNL's environmental performance during the calendar year in review. The SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and compliance, restoration, and surveillance monitoring program performance. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception in 1947. The report is available in print and as a downloadable file on the BNL web page at http://www.bnl.gov/ewms/ser/. A summary of the SER is also prepared each year to provide a general overview of the report, and is distributed with a CD of the full report.

  14. Environmental security in North-West Russia

    International Nuclear Information System (INIS)

    Bjerke, S.

    1999-01-01

    The arms race and military security during the Cold War cost trillions of dollars. It has been claimed that the processes of disarmament, and the large-scale conversion from military to civilian production that is now under way, will be equally costly. This includes the cost of environmental clean up and other measures to deal with the environmental legacy of the Cold War. Norway strongly supports a holistic approach to environmental issues. The armed forces and military industry must also adapt to environmental demands and adopt the principles of modern environmental management. Our own defence forces have for some time been basing their choice of equipment partly on modern environmental criteria and are taking steps to remedy previous environmental damage. Field training and exercises are subject to stringent environmental restrictions. All along the former East-West divide the scope of military activity has been dramatically reduced. The time has come to focus more attention on military or arms-related environmental issues

  15. Federal environmental inspections handbook

    International Nuclear Information System (INIS)

    1991-10-01

    This Federal Environmental Inspection Handbook has been prepared by the Department of Energy (DOE), Office of Environmental Guidance, RCRA/CERCLA Division (EH-231). It is designed to provide DOE personnel with an easily accessible compilation of the environmental inspection requirements under Federal environmental statutes which may impact DOE operations and activities. DOE personnel are reminded that this Handbook is intended to be used in concert with, and not as a substitute for, the Code of Federal Regulations (CFR). Federal Register (FR), and other applicable regulatory documents

  16. PRODUCING IN COMPLIANCE WITH ENVIRONMENTAL ...

    African Journals Online (AJOL)

    with this objective, different Ethiopian environmental laws, together with the ... gravity of impact to the environment. Brewery is one of such industrial sectors that is subjected to environmental regulation according to environmental laws.This paper ... Brewery wastes are generated in liquid, gaseous, and solid form. The liquid.

  17. Site Environmental Report for 2015

    Energy Technology Data Exchange (ETDEWEB)

    Pauer, Ron O. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Baskin, David A. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Borglin, Ned K. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Fox, Robert A. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Harvey, Zachary R. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Jelinski, John A. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Kassis, Maram M. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Muhlholland, Brendan J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Thorson, Patrick A. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Xu, Suying Y. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sutherland, Nancy L. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Wehle, Petra C. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2016-09-30

    The annual Site Environmental Report documents Lawrence Berkeley National Laboratory’s performance in reducing its environmental impacts, progress toward cleaning up groundwater contamination, and compliance with applicable Department of Energy, federal, state, and local environmental regulations. The report is required by DOE Order 231.1B, Environment, Safety, and Health Reporting.

  18. Release monitoring and environmental surveillance of Cea centers. Assessment and regulation and method 1999; Controle des rejets et surveillance de l'environnement des centres CEA. Bilan et reglementation et methode 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    The quality of the natural environment around the centers of the Commissariat a l Energie Atomique is an important point of its safety policy. The environmental protection is based on the control of risks coming from research and development activities of its installations. It aims to reduce as low as possible, the impact of its activities on man and his environment. This publication develops the sampling and measurement methods that are made on effluents and in environment, according to the radionuclides characteristics, that are present. It gives also the regulation that applied to the effluents monitoring. The results of radioactive effluents releases (liquid and gaseous) and the surveillance of environment around cea centers is given in the 'Bilan 1999' publication. An analysis of these results on the 1995-1999 period allows to follow their evolution. (N.C.)

  19. Nuclear power plant Isar. Actualized environmental statement 2012 on the consolidated environmental statement 2010

    International Nuclear Information System (INIS)

    2012-01-01

    The actualized environmental statement 2012 for the NPP Isar covers the following issues: Direct environmental aspects: heat dissipation to the environment, water management, radioactive matter release onto the environment, environmental monitoring, waste management, operational materials supply, radioactive materials transport, safety of the nuclear facilities, remote monitoring and information system, environmental protection, communication; indirect environmental aspects; core indicators according EMAS III, development of the environmental targets and programs, reference to the valid environmental regulations, declaration of the environmental consultant.

  20. Importance of investigating epigenetic alterations for industry and regulators: An appraisal of current efforts by the Health and Environmental Sciences Institute

    International Nuclear Information System (INIS)

    Miousse, Isabelle R.; Currie, Richard; Datta, Kaushik; Ellinger-Ziegelbauer, Heidrun; French, John E.; Harrill, Alison H.; Koturbash, Igor; Lawton, Michael; Mann, Derek; Meehan, Richard R.; Moggs, Jonathan G.; O’Lone, Raegan; Rasoulpour, Reza J.

    2015-01-01

    Recent technological advances have led to rapid progress in the characterization of epigenetic modifications that control gene expression in a generally heritable way, and are likely involved in defining cellular phenotypes, developmental stages and disease status from one generation to the next. On November 18, 2013, the International Life Sciences Institute (ILSI) Health and Environmental Sciences Institute (HESI) held a symposium entitled “Advances in Assessing Adverse Epigenetic Effects of Drugs and Chemicals” in Washington, D.C. The goal of the symposium was to identify gaps in knowledge and highlight promising areas of progress that represent opportunities to utilize epigenomic profiling for risk assessment of drugs and chemicals. Epigenomic profiling has the potential to provide mechanistic information in toxicological safety assessments; this is especially relevant for the evaluation of carcinogenic or teratogenic potential and also for drugs that directly target epigenetic modifiers, like DNA methyltransferases or histone modifying enzymes. Furthermore, it can serve as an endpoint or marker for hazard characterization in chemical safety assessment. The assessment of epigenetic effects may also be approached with new model systems that could directly assess transgenerational effects or potentially sensitive stem cell populations. These would enhance the range of safety assessment tools for evaluating xenobiotics that perturb the epigenome. Here we provide a brief synopsis of the symposium, update findings since that time and then highlight potential directions for future collaborative efforts to incorporate epigenetic profiling into risk assessment

  1. Regulation of FoxO transcription factors by environmental NO(x). Influence of metal ions and polycyclic aromatic hydrocarbons; Regulation von FoxO-Transkriptionsfaktoren durch Umweltnoxen. Einfluss von Metallionen und polyzyklischen aromatischen Kohlenwasserstoffen

    Energy Technology Data Exchange (ETDEWEB)

    Eckers, Anna

    2009-12-15

    FoxO transcription factors are crucial modulators of various cellular processes, controlling the expression of target genes such as those coding for manganese superoxide dismutase (MnSOD) and selenoprotein P (SeP), thereby supporting defense against oxidative stress. Environmental stimuli such as heavy metal ions and polycyclic aromatic hydrocarbons (PAH) modulate signaling pathways both by interaction with proteins or by inducing the generation of reactive oxygen species (ROS). Exposure of hepatoma cells to nickel ions at subcytotoxic doses did not translate into modulation of FoxO activity despite an activation of the Ser/Thr-kinase Akt. The cellular response to nickel ions under these conditions is most likely independent of the formation of ROS, since there were no increased levels of glutathione disulfide detectable. FoxO activity was then found to be modulated in response to exposure of cells to PAH or the tryptophan photoproduct FICZ. Both PAH and FICZ caused an increased activity of a FoxO-responsive promoter construct as well as of glucose 6-phosphatase promoter activity. In contrast, the activities of promoters of genes coding for MnSOD or SeP were decreased in response to exposure to the PAH 3-methylcholanthrene (3-MC). In line with the promoter effects, 3-MC also decreased steady-state levels of SeP mRNA. The response of the SeP promoter to 3-MC was abrogated by point mutations introduced at the two identified FoxO binding elements of the SeP promoter, implying that interaction of FoxO proteins with these sites is essential for the downregulation of promoter activity. In addition to FoxO activity being modulated by xenobiotics, it was then demonstrated that FoxO expression was also modulated by exposure of cells to PAH or FICZ. FoxO4 mRNA levels were downregulated in hepatoma cells exposed to 3-MC or FICZ. Similarly, insulin treatment caused a downregulation of mRNA levels of FoxO 1a, 3a and 4 in hepatoma cells. (orig.)

  2. Effects of antihistamine on up-regulation of histamine H1 receptor mRNA in the nasal mucosa of patients with pollinosis induced by controlled cedar pollen challenge in an environmental exposure unit

    Directory of Open Access Journals (Sweden)

    Yoshiaki Kitamura

    2015-11-01

    Full Text Available In the present study, we examined the effects of antihistamine on the up-regulation of H1R mRNA in the nasal mucosa of patients with pollinosis induced by controlled exposure to pollen using an environmental exposure unit. Out of 20 patients, we designated 14 responders, whose levels of H1R mRNA in the nasal mucosa were increased after the first pollen exposure and excluded 6 non-responders. Accordingly, the first exposure to pollen without treatment significantly induced both nasal symptoms and the up-regulation of H1R mRNA in the nasal mucosa of the responders. Subsequently, prophylactic administration of antihistamine prior to the second pollen exposure significantly inhibited both of the above effects in the responders. Moreover, the nasal expression of H1R mRNA before the second pollen exposure in the responders pretreated with antihistamine was significantly decreased, as compared with that before the first pollen exposure without treatment. These findings suggest that antihistamines suppressed histamine-induced transcriptional activation of H1R gene in the nasal mucosa, in addition to their blocking effect against histamine on H1R, resulting in a decrease of nasal symptoms. These findings further suggest that by their inverse agonistic activity, antihistamines suppress the basal transcription of nasal H1R in the absence of histamine in responders.

  3. Effects of antihistamine on up-regulation of histamine H1 receptor mRNA in the nasal mucosa of patients with pollinosis induced by controlled cedar pollen challenge in an environmental exposure unit.

    Science.gov (United States)

    Kitamura, Yoshiaki; Nakagawa, Hideyuki; Fujii, Tatsuya; Sakoda, Takema; Enomoto, Tadao; Mizuguchi, Hiroyuki; Fukui, Hiroyuki; Takeda, Noriaki

    2015-11-01

    In the present study, we examined the effects of antihistamine on the up-regulation of H1R mRNA in the nasal mucosa of patients with pollinosis induced by controlled exposure to pollen using an environmental exposure unit. Out of 20 patients, we designated 14 responders, whose levels of H1R mRNA in the nasal mucosa were increased after the first pollen exposure and excluded 6 non-responders. Accordingly, the first exposure to pollen without treatment significantly induced both nasal symptoms and the up-regulation of H1R mRNA in the nasal mucosa of the responders. Subsequently, prophylactic administration of antihistamine prior to the second pollen exposure significantly inhibited both of the above effects in the responders. Moreover, the nasal expression of H1R mRNA before the second pollen exposure in the responders pretreated with antihistamine was significantly decreased, as compared with that before the first pollen exposure without treatment. These findings suggest that antihistamines suppressed histamine-induced transcriptional activation of H1R gene in the nasal mucosa, in addition to their blocking effect against histamine on H1R, resulting in a decrease of nasal symptoms. These findings further suggest that by their inverse agonistic activity, antihistamines suppress the basal transcription of nasal H1R in the absence of histamine in responders. Copyright © 2015 Japanese Pharmacological Society. Production and hosting by Elsevier B.V. All rights reserved.

  4. Hanford Site 1998 Environmental Report

    Energy Technology Data Exchange (ETDEWEB)

    RL Dirkes; RW Hanf; TM Poston

    1999-09-21

    This Hanford Site environmental report is prepared annually to summarize environmental data and information, to describe environmental management performance, to demonstrate the status of compliance with environmental regulations, and to highlight major environmental programs and efforts. The report is written to meet requirements and guidelines of the U.S. Department of Energy (DOE) and to meet the needs of the public. This summary has been written with a minimum of technical terminology. Individual sections of the report are designed to: describe the Hanford Site and its mission; summarize the status of compliance with environmental regulations; describe the environmental programs at the Hanford Site; discuss the estimated radionuclide exposure to the public from 1998 Hanford Site activities; present the effluent monitoring, environmental surveillance, and groundwater protection and monitoring information; and discuss the activities to ensure quality.

  5. Hanford Site Environmental Report 1993

    International Nuclear Information System (INIS)

    Dirkes, R.L.; Hanf, R.W.; Woodruff, R.K.

    1994-06-01

    The Hanford Site Environmental Report is prepared annually to summarize environmental data and information, describe environmental management performance, and demonstrate the status of compliance with environmental regulations. The report also highlights major environmental programs and efforts. The report is written to meet reporting requirements and Guidelines of the U.S. Department of Energy (DOE) an to meet the needs of the public. This summary has been written with a minimum of technical terminology. Individual sections of the report are designed to (a) describe the Hanford Site and its mission, (b) summarize the status in 1993 of compliance with environmental regulations, (c) describe the environmental programs at the Hanford Site, (d) discuss estimated radionuclide exposure to the public from 1993 Hanford activities, (e) present information on effluent monitoring and environmental surveillance, including ground-water protection and monitoring, (f) discuss activities to ensure quality. More detailed information can be found in the body of the report, the appendixes, and the cited references

  6. Hanford Site Environmental Report 1999

    Energy Technology Data Exchange (ETDEWEB)

    TM Poston; RW Hanf; RL Dirkes

    2000-09-28

    This Hanford Site environmental report is prepared annually to summarize environmental data and information, to describe environmental management performance, to demonstrate the status of compliance with environmental regulations, and to highlight major environmental programs and efforts. The report is written to meet requirements and guidelines of the U.S. Department of Energy (DOE) and to meet the needs of the public. This summary has been written with a minimum of technical terminology. Individual sections of the report are designed to: (1) describe the Hanford Site and its mission; (2) summarize the status of compliance with environmental regulations; (3) describe the environmental programs at the Hanford Site; (4) discuss the estimated radionuclide exposure to the public from 1999 Hanford Site activities; (5) present the effluent monitoring, environmental surveillance, groundwater protection and monitoring information; and (6) discuss the activities to ensure quality.

  7. Hanford Site Environmental Report 1999

    International Nuclear Information System (INIS)

    Poston, TM; Hanf, RW; Dirkes, RL

    2000-01-01

    This Hanford Site environmental report is prepared annually to summarize environmental data and information, to describe environmental management performance, to demonstrate the status of compliance with environmental regulations, and to highlight major environmental programs and efforts. The report is written to meet requirements and guidelines of the U.S. Department of Energy (DOE) and to meet the needs of the public. This summary has been written with a minimum of technical terminology. Individual sections of the report are designed to: (1) describe the Hanford Site and its mission; (2) summarize the status of compliance with environmental regulations; (3) describe the environmental programs at the Hanford Site; (4) discuss the estimated radionuclide exposure to the public from 1999 Hanford Site activities; (5) present the effluent monitoring, environmental surveillance, groundwater protection and monitoring information; and (6) discuss the activities to ensure quality

  8. Hanford Site Environmental Report 1993

    Energy Technology Data Exchange (ETDEWEB)

    Dirkes, R.L.; Hanf, R.W.; Woodruff, R.K. [eds.

    1994-06-01

    The Hanford Site Environmental Report is prepared annually to summarize environmental data and information, describe environmental management performance, and demonstrate the status of compliance with environmental regulations. The report also highlights major environmental programs and efforts. The report is written to meet reporting requirements and Guidelines of the U.S. Department of Energy (DOE) an to meet the needs of the public. This summary has been written with a minimum of technical terminology. Individual sections of the report are designed to (a) describe the Hanford Site and its mission, (b) summarize the status in 1993 of compliance with environmental regulations, (c) describe the environmental programs at the Hanford Site, (d) discuss estimated radionuclide exposure to the public from 1993 Hanford activities, (e) present information on effluent monitoring and environmental surveillance, including ground-water protection and monitoring, (f) discuss activities to ensure quality. More detailed information can be found in the body of the report, the appendixes, and the cited references.

  9. 10 CFR 51.30 - Environmental assessment.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Environmental assessment. 51.30 Section 51.30 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy Act-Regulations Implementing Section 102(2...

  10. Company environmental communication

    International Nuclear Information System (INIS)

    Andriola, L.; Luciani, R.; Borghini, S.

    2001-01-01

    Environmental communication is becoming a sine qua non for companies which are more and more pressed by the need to reinforce communication with interested parties: environmental groups, local communities, local and national authorities, employees, share-holders, banks, insurance companies, customers and consumers. Reliable environmental information, just like economical and property data, is now required during both company take-over and financing, and in some cases it can affect insurance premiums. In fact, environmental guarantees are more and more often required because breaching environmental regulations can entail legal sanctions going as far as suspension of business. There now also Green investment funds that engage their resources only against specific environmental guarantees on the part of the companies that, before being selected for the investment, are submitted to rather accurate questionnaires by the investment manager [it

  11. Environmental Regulatory Compliance Plan for Site Characterization

    International Nuclear Information System (INIS)

    1988-12-01

    The DOE is committed to conduct its operations in an environmentally safe and sound manner, and will comply with applicable environmental statutes and regulations. These objectives are described in DOE Order 5400.1 (Environmental Protection Program Requirements). This document -- the Environmental Regulatory Compliance Plan (ERCP) -- is one method of implementing the policy set forth in DOE Order 5400.1 and the NWPA. The ERCP describes the plan by which the DOE will comply with applicable Federal environmental statutes and regulations. The ERCP also discusses how DOE will address State and local environmental statutes and regulations. 180 refs., 27 figs., 1 tab

  12. Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception.

    Directory of Open Access Journals (Sweden)

    G Gregory Neely

    Full Text Available The ability to perceive noxious stimuli is critical for an animal's survival in the face of environmental danger, and thus pain perception is likely to be under stringent evolutionary pressure. Using a neuronal-specific RNAi knock-down strategy in adult Drosophila, we recently completed a genome-wide functional annotation of heat nociception that allowed us to identify α2δ3 as a novel pain gene. Here we report construction of an evolutionary-conserved, system-level, global molecular pain network map. Our systems map is markedly enriched for multiple genes associated with human pain and predicts a plethora of novel candidate pain pathways. One central node of this pain network is phospholipid signaling, which has been implicated before in pain processing. To further investigate the role of phospholipid signaling in mammalian heat pain perception, we analysed the phenotype of PIP5Kα and PI3Kγ mutant mice. Intriguingly, both of these mice exhibit pronounced hypersensitivity to noxious heat and capsaicin-induced pain, which directly mapped through PI3Kγ kinase-dead knock-in mice to PI3Kγ lipid kinase activity. Using single primary sensory neuron recording, PI3Kγ function was mechanistically linked to a negative regulation of TRPV1 channel transduction. Our data provide a systems map for heat nociception and reinforces the extraordinary conservation of molecular mechanisms of nociception across different species.

  13. Regulation of on-tree vitamin E biosynthesis in olive fruit during successive growing years: the impact of fruit development and environmental cues

    Directory of Open Access Journals (Sweden)

    Egli Christou Georgiadou

    2016-11-01

    Full Text Available The term vitamin E refers to a group of eight lipophilic compounds known as tocochromanols. The tocochromanols are divided into two groups, that is, tocopherols and tocotrienols, with four forms each, namely α-, β-, γ-, and δ-. In order to explore the temporal biosynthesis of tocochromanols in olive (Olea europaea cv. ‘Koroneiki’ fruit during on-tree development and ripening over successive growing years, a combined array of analytical, molecular, bioinformatic, immunoblotting and antioxidant techniques were employed. Fruits were harvested at eight successive developmental stages (10-30 weeks after flowering (WAF, over three consecutive years. Intriguingly, climatic conditions affected relative transcription levels of vitamin E biosynthetic enzymes; a general suppression to induction pattern (excluding VTE5 was monitored moving from the 1st to the 3rd growing year, probably correlated to decreasing rainfall levels and higher temperature, particularly at the fruit ripening stage. A gradual diminution of VTE5 protein content was detected during the fruit development of each year, with a marked decrease occurring after 16 WAF. Alpha-tocopherol was the most abundant metabolite with an average percentage of 96.82 ± 0.23%, 91.13 ± 0.95% and 88.53 ± 0.96% (during the 1st, 2nd and 3rd year, respectively of total vitamin E content in 10–30 WAF. The concentrations of α-tocopherol revealed a generally declining pattern, both during the on-tree ripening of the olive fruit and across the three years, accompanied by a parallel decline of the total antioxidant activity of the drupe. Contrarily, all other tocochromanols demonstrated an inverse pattern with lowest levels being recorded during the 1st year. It is likely that, in a defense attempt against water deficit conditions and increased air temperature, transcription of genes involved in vitamin E biosynthesis (excluding VTE5 is up-regulated in olive fruit, probably leading to the blocking

  14. ENVIRONMENTAL ACCOUNTING, AN ENVIRONMENTAL PROTECTION INSTRUMENT USED BY ENTITIES

    Directory of Open Access Journals (Sweden)

    IONELA CORNELIA STANCIU

    2011-01-01

    Full Text Available The purpose of this article is to present certain aspects regarding environmental accounting and the environmental costs, which are instruments that the entities can use to identify and prevent the effects of their activities on the environment. The main objectives aimed by the article were to present the state of knowledge starting with the 1970s, when the concept of environmental accounting emerged for the first time, up until now; to define the concepts of environmental accounting and environmental costs; to present an analysis of how economic agents in Romania, and implicitly, accounting regulations, are getting involved in environmental issues.

  15. Surface Environmental Surveillance Procedures Manual

    Energy Technology Data Exchange (ETDEWEB)

    RW Hanf; TM Poston

    2000-09-20

    Environmental surveillance data are used in assessing the impact of current and past site operations on human health and the environment, demonstrating compliance with applicable local, state, and federal environmental regulations, and verifying the adequacy of containment and effluent controls. SESP sampling schedules are reviewed, revised, and published each calendar year in the Hanford Site Environmental Surveillance Master Sampling Schedule. Environmental samples are collected by SESP staff in accordance with the approved sample collection procedures documented in this manual.

  16. Mars Surface Environmental Issues

    Science.gov (United States)

    Charles, John

    2002-01-01

    Planetary exploration by astronauts will require extended periods of habitation on a planet's surface, under the influence of environmental factors that are different from those of Earth and the spacecraft that delivered the crew to the planet. Human exploration of Mars, a possible near-term planetary objective, can be considered a challenging scenario. Mission scenarios currently under consideration call for surface habitation periods of from 1 to 18 months on even the earliest expeditions. Methods: Environmental issues associated with Mars exploration have been investigated by NASA and the National Space Biomedical Research Institute (NSBRI) as part of the Bioastronautics Critical Path Roadmap Project (see http ://criticalpath.jsc.nasa.gov). Results: Arrival on Mars will immediately expose the crew to gravity only 38% of that at Earth's surface in possibly the first prolonged exposure to gravity other than the 1G of Earth's surface and the zero G of weightless space flight, with yet unknown effects on crew physiology. The radiation at Mars' surface is not well documented, although the planet's bulk and even its thin atmosphere may moderate the influx of galactic cosmic radiation and energetic protons from solar flares. Secondary radiation from activated components of the soil must also be considered. Ultrafine and larger respirable and nonrespirable particles in Martian dust introduced into the habitat after surface excursions may induce pulmonary inflammation exacerbated by the additive reactive and oxidizing nature of the dust. Stringent decontamination cannot eliminate mechanical and corrosive effects of the dust on pressure suits and exposed machinery. The biohazard potential of putative indigenous Martian microorganisms may be assessed by comparison with analog environments on Earth. Even in their absence, human microorganisms, if not properly controlled, can be a threat to the crew's health. Conclusions: Mars' surface offers a substantial challenge to the

  17. Environmental concerns of deforestation

    International Nuclear Information System (INIS)

    Rahman, A.

    1995-01-01

    The loss of forests as a result of deforestation is a serious problem in Pakistan as well as in other developing world. The forests play important role in environmental protection through soil conservation, regulation of hydrological cycles and micro climate amelioration. At the global scale, forests act as carbon sinks, maintain biodiversity and regulate climate, especially in the context of greenhouse effect. The deforestation should be countered through enforcement of strict laws and elaborating environmental role of forests through media and local councils. Various economic analysis indicate that tropical forests have greater overall benefits if left intact, rather than destroying them for timber. (author)

  18. Environmental fiscal reforms

    OpenAIRE

    Ashish Chaturvedi; Manjeet S. Saluja; Abhijit Banerjee; Rachna Arora

    2014-01-01

    The paper presents concepts and instruments of environmental fiscal reforms (EFR) and their application in the Indian context. EFR can lead to environmental improvement more efficiently and cost effectively than traditional regulation. There is substantial experience of successful EFR implementation in the European Union. India has also adopted some EFR measures such as deregulation of petrol prices, coal cess, and subsidy for setting up common effluent treatment plants. The challenges of imp...

  19. Environmental guidance regulatory bulletin

    International Nuclear Information System (INIS)

    1997-01-01

    This document describes the background on expanding public participation in the Resource Conservation and Recovery Act and DOE's response. The bulletin also describes the changes made by the final rule to existing regulations, guidance provided by EPA in the preamble and in the revised RCRA Public Participation Manual, the relationship between public participation and environmental justice, and DOE's recent public participation and environmental justice initiatives

  20. ICAM-1 and AMPK regulate cell detachment and apoptosis by N-methyl-N′-nitro-N-nitrosoguanidine, a widely spread environmental chemical, in human hormone-refractory prostate cancers

    International Nuclear Information System (INIS)

    Chen, Yi-Cheng; Lu, Pin-Hsuan; Hsu, Jui-Ling; Yu, Chia-Chun; Guh, Jih-Hwa

    2011-01-01

    Poly(ADP-ribose) polymerase-1 (PARP-1), a sensor of DNA damage, plays a crucial role in the regulation of DNA repair. PARP-1 hyperactivation causes DNA damage and cell death. The underlying mechanism is complicated and is through diverse pathways. The understanding of responsible signaling pathways may offer implications for effective therapies. After concentration-response determination of N-Methyl-N′-Nitro-N-Nitrosoguanidine (MNNG, a PARP-1 activating agent and an environmental mutagen) in human hormone-refractory prostate cancers, the data showed that concentrations below 5 μM did not change cell survival but cause a time-dependent up-regulation of intracellular adhesion molecule-1 (ICAM-1) in mRNA, total protein and cell surface levels. Detection of phosphorylation and degradation of IκB-α and nuclear translocation of NF-κB showed that MNNG induced the activation of NF-κB that was responsible for the ICAM-1 up-regulation since PDTC (a NF-κB inhibitor) significantly abolished this effect. However, higher concentrations (e.g., 10 μM) of MNNG induced a 61% detachment of the cells which were apoptosis associated with the activation of AMP-activated protein kinase (AMPK), c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK). Further identification showed that both AMPK and JNK other than p38 MAPK functionally contributed to cell death. The remaining 39% attached cells were survival associated with high ICAM-1 expression. In conclusion, the data suggest that NF-κB-dependent up-regulation of ICAM-1 plays a key role on cell attachment and survival; whereas, activation of AMPK and JNK participates in cytotoxic signaling pathways in detached cells caused by PARP-1 activation. Highlights: ► Low level of DNA damage helps cell attachment and survival via ICAM-1 upregulation. ► High level of DNA damage causes AMPK- and JNK-involved cell detachment and death. ► The study provides an anticancer approach targeting PARP-1 and DNA damage

  1. Market, Regulation, Market, Regulation

    DEFF Research Database (Denmark)

    Frankel, Christian; Galland, Jean-Pierre

    2015-01-01

    This paper focuses on the European Regulatory system which was settled both for opening the Single Market for products and ensuring the consumers' safety. It claims that the New Approach and Standardization, and the Global Approach to conformity assessment, which suppressed the last technical...... barriers to trade in Europe, realized the free movement of products by organizing progressively several orders of markets and regulation. Based on historical and institutional documents, on technical publications, and on interviews, this article relates how the European Commission and the Member States had...... alternatively recourse to markets and to regulations, at the three main levels of the New Approach Directives implementation. The article focuses also more specifically on the Medical Devices sector, not only because this New Approach sector has long been controversial in Europe, and has recently been concerned...

  2. From bioavailability science to regulation of organic chemicals

    NARCIS (Netherlands)

    Ortega-Calvo, J.J.; Harmsen, J.; Parsons, J.R.; Semple, K.T.; Aitkin, M.D.; Ajao, C.; Eadsforth, C.; Galay-Burgos, M.; Naidu, R.; Oliver, R.; Peijnenburg, W.J.G.M.; Römbke, J.; Streck, G.; Versonnen, B.

    2015-01-01

    The bioavailability of organic chemicals in soil and sediment is an important area of scientific investigation for environmental scientists, although this area of study remains only partially recognized by regulators and industries working in the environmental sector. Regulators have recently

  3. Environmental Aesthetics

    DEFF Research Database (Denmark)

    Svabo, Connie; Ekelund, Kathrine

    2015-01-01

    The philosophical subfield environmental aesthetics can contribute to the design of sustainable futures. Environmental aesthetics provides a conceptual framework for understanding the relationship between nature and culture. Current positions in environmental aesthetics are lined out and used...

  4. Environmental recordkeeping: The administrative record

    Energy Technology Data Exchange (ETDEWEB)

    Sprouse, B.S.

    1991-08-01

    This document provides information on an environmental records management system. It includes information on environmental recordkeeping; environmental regulations with emphasis on the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA); and the administrative record including a case study of the Hanford Site's administrative record system. This paper will focus on the following objectives: (1) Identify resources that can be used as reference tools; (2) understand the reasons for developing and maintaining an administrative record; and, (3) evaluate an existing system and identify means of complying with the regulations. 15 refs., 2 figs.

  5. Environmental recordkeeping: The administrative record

    International Nuclear Information System (INIS)

    Sprouse, B.S.

    1991-08-01

    This document provides information on an environmental records management system. It includes information on environmental recordkeeping; environmental regulations with emphasis on the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA); and the administrative record including a case study of the Hanford Site's administrative record system. This paper will focus on the following objectives: (1) Identify resources that can be used as reference tools; (2) understand the reasons for developing and maintaining an administrative record; and, (3) evaluate an existing system and identify means of complying with the regulations. 15 refs., 2 figs

  6. Life cycle environmental impacts of UK shale gas

    International Nuclear Information System (INIS)

    Stamford, Laurence; Azapagic, Adisa

    2014-01-01

    Highlights: • First full life cycle assessment of shale gas used for electricity generation. • Comparison with coal, conventional and liquefied gas, nuclear, wind and solar PV. • Shale gas worse than coal for three impacts and better than renewables for four. • It has higher photochemical smog and terrestrial toxicity than the other options. • Shale gas a sound environmental option only if accompanied by stringent regulation. - Abstract: Exploitation of shale gas in the UK is at a very early stage, but with the latest estimates suggesting potential resources of 3.8 × 10 13 cubic metres – enough to supply the UK for next 470 years – it is viewed by many as an exciting economic prospect. However, its environmental impacts are currently unknown. This is the focus of this paper which estimates for the first time the life cycle impacts of UK shale gas, assuming its use for electricity generation. Shale gas is compared to fossil-fuel alternatives (conventional gas and coal) and low-carbon options (nuclear, offshore wind and solar photovoltaics). The results suggest that the impacts range widely, depending on the assumptions. For example, the global warming potential (GWP100) of electricity from shale gas ranges from 412 to 1102 g CO 2 -eq./kWh with a central estimate of 462 g. The central estimates suggest that shale gas is comparable or superior to conventional gas and low-carbon technologies for depletion of abiotic resources, eutrophication, and freshwater, marine and human toxicities. Conversely, it has a higher potential for creation of photochemical oxidants (smog) and terrestrial toxicity than any other option considered. For acidification, shale gas is a better option than coal power but an order of magnitude worse than the other options. The impact on ozone layer depletion is within the range found for conventional gas, but nuclear and wind power are better options still. The results of this research highlight the need for tight regulation and

  7. Policies and procedures for considering environmental impacts

    Science.gov (United States)

    2006-03-20

    This order updates the FAA agency-wide policies and procedures for compliance with the : National Environmental Policy Act (NEPA) and implementing regulations issued by the Council : on Environmental Quality (40 CFR parts 1500-1508). The provisions o...

  8. Environmental Sampling, Monitoring and Site Assessment Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — Quality Data Asset includes all current and historical data on environmental quality with regard to the presence of radiological contamination of all kinds regulated...

  9. Annual Site Environmental Report (ASER 1999)

    Energy Technology Data Exchange (ETDEWEB)

    Holden, Gene

    2000-08-28

    This report provides information about environmental programs and compliance with environmental regulations in calendar year 1999 (CY99) at the Stanford Linear Accelerator Center (SLAC). The most noteworthy information in this report is summarized in this section.

  10. 24 CFR 983.58 - Environmental review.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Environmental review. 983.58... DEVELOPMENT PROJECT-BASED VOUCHER (PBV) PROGRAM Selection of PBV Owner Proposals § 983.58 Environmental review. (a) HUD environmental regulations. Activities under the PBV program are subject to HUD environmental...

  11. 24 CFR 582.230 - Environmental review.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Environmental review. 582.230... Environmental review. (a) Activities under this part are subject to HUD environmental regulations in part 58 of this title, except that HUD will perform an environmental review in accordance with part 50 of this...

  12. 24 CFR 583.230 - Environmental review.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Environmental review. 583.230... § 583.230 Environmental review. (a) Activities under this part are subject to HUD environmental regulations in part 58 of this title, except that HUD will perform an environmental review in accordance with...

  13. 2013 BNL Site Environmental Report. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Ratel, K.; Remien, J.; Pohlot, P.; Williams, J.; Green, T.; Paquette, P.; Dorsch, W.; Welty, T.; Burke, J.

    2014-10-01

    A summary of Brookhaven National Laboratory’s (BNL) Site Environmental Report, meant to inform the public, regulators, employees, and other stakeholders of the Laboratory’s environmental performance in the lab’s surrounding area during the calendar year. The review is comprised of multiple volumes relevant to environmental data/environmental management performance and groundwater status report.

  14. 2003 SITE ENVIRONMENTAL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    ENVIRONMENT AND WASTE MANAGMENT SERVICES DIVISION; ET AL.

    2004-10-01

    Each year, Brookhaven National Laboratory (BNL), a multi-program national laboratory, prepares an annual Site Environmental Report (SER) in accordance with Order 231.1A, Environment, Safety and Health Reporting, of the U.S. Department of Energy (DOE). The SER is written to inform outside regulators, the public, and Laboratory employees of BNL's environmental performance during the calendar year in review, and to summarize BNL's on-site environmental data; environmental management performance; compliance with applicable DOE, Environmental Protection Agency (EPA), state, and local regulations; and environmental, restoration, and surveillance monitoring programs. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception in 1947. This report is intended to be a technical document. It is available in print and as a downloadable file on the BNL web page at http://www.bnl.ser.htm. A summary of the SER is also prepared each year to provide a general overview, and is distributed with a CD version of the full-length SER. The summary supports BNL's educational and community outreach program.

  15. Environmental Compliance Guide

    International Nuclear Information System (INIS)

    1981-02-01

    The Guide is intended to assist Department of Energy personnel by providing information on the NEPA process, the processes of other environmental statutes that bear on the NEPA process, the timing relationships between the NEPA process and these other processes, as well as timing relationships between the NEPA process and the development process for policies, programs, and projects. This information should be helpful not only in formulating environmental compliance plans but also in achieving compliance with NEPA and various other environmental statutes. The Guide is divided into three parts with related appendices: Part I provides guidance for developing environmental compliance plans for DOE actions; Part II is devoted to NEPA with detailed flowcharts depicting the compliance procedures required by CEQ regulations and Department of Energy NEPA Guidelines; and Part III contains a series of flowcharts for other Federal environmental requirements that may apply to DOE projects

  16. Environmental Compliance Guide

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-02-01

    The Guide is intended to assist Department of Energy personnel by providing information on the NEPA process, the processes of other environmental statutes that bear on the NEPA process, the timing relationships between the NEPA process and these other processes, as well as timing relationships between the NEPA process and the development process for policies, programs, and projects. This information should be helpful not only in formulating environmental compliance plans but also in achieving compliance with NEPA and various other environmental statutes. The Guide is divided into three parts with related appendices: Part I provides guidance for developing environmental compliance plans for DOE actions; Part II is devoted to NEPA with detailed flowcharts depicting the compliance procedures required by CEQ regulations and Department of Energy NEPA Guidelines; and Part III contains a series of flowcharts for other Federal environmental requirements that may apply to DOE projects.

  17. Environmental audit guidelines for pipelines

    International Nuclear Information System (INIS)

    1991-01-01

    Environmental auditing is a form of management control which provides an objective basis by which a company can measure the degree of compliance with environmental regulations. Other benefits of this type of auditing include improved environmental management, furthering communication on environmental issues of concern within the company, and provision of documentation on environmental diligence. A series of environmental audit guidelines for pipelines is presented in the form of lists of questions to be asked during an environmental audit followed by recommended actions in response to those questions. The questions are organized into seven main categories: environmental management and planning; operating procedures; spill prevention; management of wastes and hazardous materials; environmental monitoring; construction of pipelines; and pipeline abandonment, decommissioning and site reclamation

  18. Vehicle recycling regulations

    DEFF Research Database (Denmark)

    Smink, Carla

    2007-01-01

    The number of end-of-life vehicles (ELVs) in the EU is increasing continously. Around 75 percent of an ELV are recyclable metals. The forecast growth in the number of ELVs calls for regulation that aims to minimise the environmental impact of a car. Using Denmark as an example, this article...

  19. The challenge of legitimizing spatially differentiated regulation

    DEFF Research Database (Denmark)

    Thorsøe, Martin Hvarregaard; Graversgaard, Morten; Noe, Egon

    2017-01-01

    to the legitimacy of agri-environmental regulation that occurs when the regulatory regime changes from general regulation to differentiated regulation. The analysis is based on a case study of the implementation of the Buffer zone act in Denmark – a regulation that prevents agricultural production in a 10 (later 9...

  20. Epigenetic regulation of persistent pain

    Science.gov (United States)

    Bai, Guang; Ren, Ke; Dubner, Ronald

    2014-01-01

    Persistent or chronic pain is tightly associated with various environmental changes and linked to abnormal gene expression within cells processing nociceptive signaling. Epigenetic regulation governs gene expression in response to environmental cues. Recent animal model and clinical studies indicate that epigenetic regulation plays an important role in the development/maintenance of persistent pain and, possibly the transition of acute pain to chronic pain, thus shedding light in a direction for development of new therapeutics for persistent pain. PMID:24948399

  1. International environmental agreements

    NARCIS (Netherlands)

    de Zeeuw, Aart

    2015-01-01

    The regulation of environmental externalities at the global level requires international agreements between sovereign states. Game theory provides an appropriate theoretical tool for analysis. However, game theory can result in a wide range of outcomes, and therefore it is important to discuss the

  2. Environmental monitoring programme

    International Nuclear Information System (INIS)

    Schroeder, H.J.

    1981-01-01

    The tasks of the radiation protection department at a nuclear power plant are mentioned and described. Special attention is given to the environmental monitoring program. The consequences from regulations, the different items in the program and the results are described. (orig./RW)

  3. Environmental Report 2008

    International Nuclear Information System (INIS)

    Gallegos, G.; Bertoldo, N.A.; Campbell, C.G.; Cerruti, S.; Dibley, V.; Doman, J.L.; Grayson, A.R.; Jones, H.E.; Kumamoto, G.; MacQueen, D.H.; Nelson, J.C.; Paterson, L.; Revelli, M.A.; Wegrecki, A.M.; Wilson, K.; Woollett, J.

    2009-01-01

    The purposes of the Lawrence Livermore National Laboratory Environmental Report 2008 are to record Lawrence Livermore National Laboratory's (LLNL's) compliance with environmental standards and requirements, describe LLNL's environmental protection and remediation programs, and present the results of environmental monitoring at the two LLNL sites - the Livermore site and Site 300. The report is prepared for the U.S. Department of Energy (DOE) by LLNL's Environmental Protection Department. Submittal of the report satisfies requirements under DOE Order 231.1A, Environmental Safety and Health Reporting, and DOE Order 5400.5, Radiation Protection of the Public and Environment. The report is distributed electronically and is available at https://saer.lln.gov/, the website for the LLNL annual environmental report. Previous LLNL annual environmental reports beginning in 1994 are also on the website. Some references in the electronic report text are underlined, which indicates that they are clickable links. Clicking on one of these links will open the related document, data workbook, or website that it refers to. The report begins with an executive summary, which provides the purpose of the report and an overview of LLNL's compliance and monitoring results. The first three chapters provide background information: Chapter 1 is an overview of the location, meteorology, and hydrogeology of the two LLNL sites; Chapter 2 is a summary of LLNL's compliance with environmental regulations; and Chapter 3 is a description of LLNL's environmental programs with an emphasis on the Environmental Management System including pollution prevention. The majority of the report covers LLNL's environmental monitoring programs and monitoring data for 2008: effluent and ambient air (Chapter 4); waters, including wastewater, storm water runoff, surface water, rain, and groundwater (Chapter 5); and terrestrial, including soil, sediment, vegetation, foodstuff, ambient radiation, and special status

  4. 2007 Site Environmental Report

    Energy Technology Data Exchange (ETDEWEB)

    Ratel,K.

    2008-10-01

    Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of the Laboratory's environmental performance during the calendar year in review. Volume I of the SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and performance in restoration and surveillance monitoring programs. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception in 1947. Volume II of the SER, the Groundwater Status Report, also is prepared annually to report on the status of and evaluate the performance of groundwater treatment systems at the Laboratory. Volume II includes detailed technical summaries of groundwater data and its interpretation, and is intended for internal BNL users, regulators, and other technically oriented stakeholders. A brief summary of the information contained in Volume II is included in this volume in Chapter 7, Groundwater Protection. Both reports are available in print and as downloadable files on the BNL web page at http://www.bnl.gov/ewms/ser/. An electronic version on compact disc is distributed with each printed report. In addition, a summary of Volume I is prepared each year to provide a general overview of the report, and is distributed with a compact disc containing the-length report.

  5. Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation.

    Directory of Open Access Journals (Sweden)

    Nicola Gagliani

    Full Text Available BACKGROUND: A large pool of preexisting alloreactive effector T cells can cause allogeneic graft rejection following transplantation. However, it is possible to induce transplant tolerance by altering the balance between effector and regulatory T (Treg cells. Among the various Treg-cell types, Foxp3(+Treg and IL-10-producing T regulatory type 1 (Tr1 cells have frequently been associated with tolerance following transplantation in both mice and humans. Previously, we demonstrated that rapamycin+IL-10 promotes Tr1-cell-associated tolerance in Balb/c mice transplanted with C57BL/6 pancreatic islets. However, this same treatment was unsuccessful in C57BL/6 mice transplanted with Balb/c islets (classified as a stringent transplant model. We accordingly designed a protocol that would be effective in the latter transplant model by simultaneously depleting effector T cells and fostering production of Treg cells. We additionally developed and tested a clinically translatable protocol that used no depleting agent. METHODOLOGY/PRINCIPAL FINDINGS: Diabetic C57BL/6 mice were transplanted with Balb/c pancreatic islets. Recipient mice transiently treated with anti-CD45RB mAb+rapamycin+IL-10 developed antigen-specific tolerance. During treatment, Foxp3(+Treg cells were momentarily enriched in the blood, followed by accumulation in the graft and draining lymph node, whereas CD4(+IL-10(+IL-4(- T (i.e., Tr1 cells localized in the spleen. In long-term tolerant mice, only CD4(+IL-10(+IL-4(- T cells remained enriched in the spleen and IL-10 was key in the maintenance of tolerance. Alternatively, recipient mice were treated with two compounds routinely used in the clinic (namely, rapamycin and G-CSF; this drug combination promoted tolerance associated with CD4(+IL-10(+IL-4(- T cells. CONCLUSIONS/SIGNIFICANCE: The anti-CD45RB mAb+rapamycin+IL-10 combined protocol promotes a state of tolerance that is IL-10 dependent. Moreover, the combination of rapamycin+G-CSF induces

  6. Environmental requirements in thermochemical and biochemical conversion of biomass

    International Nuclear Information System (INIS)

    Frings, R.M.; Mackie, K.L.; Hunter, I.R.

    1992-01-01

    Many biological and thermochemical processing options exist for the conversion of biomass to fuels. Commercially, these options are assessed in terms of fuel product yield and quality. However, attention must also be paid to the environmental aspects of each technology so that any commercial plant can meet the increasingly stringent environmental legislation in the world today. The environmental aspects of biological conversion (biogasification and bioliquefaction) and thermal conversion (high pressure liquefaction, flash pyrolysis, and gasification) are reviewed. Biological conversion processes are likely to generate waste streams which are more treatable than those from thermal conversion processes but the available data for thermal liquefaction are very limited. Close attention to waste minimisation is recommended and processing options that greatly reduce or eliminate waste streams have been identified. Product upgrading and its effect on wastewater quality also requires attention. Emphasis in further research studies needs to be placed on providing authentic waste streams for environmental assessment. (author)

  7. Surface Environmental Surveillance Procedures Manual

    International Nuclear Information System (INIS)

    Hanf, Robert W.; Poston, Ted M.

    2000-01-01

    Shows and explains certain procedures needed for surface environmental surveillance. Hanford Site environmental surveillance is conducted by the Pacific Northwest National Laboratory (PNNL) for the U.S. Department of Energy (DOE) under the Surface Environmental Surveillance Project (SESP). The basic requirements for site surveillance are set fourth in DOE Order 5400.1, General Environmental Protection Program Requirements. Guidance for the SESP is provided in DOE Order 5484.1, Environmental Protection, Safety, and Health Protection Information Reporting Requirements and DOE Order 5400.5, Radiation Protection of the Public and Environment. Guidelines for environmental surveillance activities are provided in DOE/EH-0173T, Environmental Regulatory Guide for Radiological Effluent Monitoring and Environmental Surveillance. An environmental monitoring plan for the Hanford Site is outlined in DOE/RL 91-50 Rev. 2, Environmental Monitoring Plan, United States Department of Energy, Richland Operations Office. Environmental surveillance data are used in assessing the impact of current and past site operations on human health and the environment, demonstrating compliance with applicable local, state, and federal environmental regulations, and verifying the adequacy of containment and effluent controls. SESP sampling schedules are reviewed, revised, and published each calendar year in the Hanford Site Environmental Surveillance Master Sampling Schedule. Environmental samples are collected by SESP staff in accordance with the approved sample collection procedures documented in this manual. Personnel training requirements are documented in SESP-TP-01 Rev.2, Surface Environmental Surveillance Project Training Program.

  8. Footprints on Ammonia Concentrations from Environmental Regulations

    DEFF Research Database (Denmark)

    Skjøth, Carsten Ambelas; Ellermann, Thomas; Hertel, Ole

    2008-01-01

    Releases of ammonia (NH3) to the atmosphere contribute significantly to the desposition of nitrogen to both terrestrial and aquatic ecosystems. This is the background for the national NH3 emission ceilings in Europe. However, in some countries the national legislation aims not only to meet theese...

  9. Regulated Environmental Activity Sites - CriticalErosion

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Created based on the Critical Erosion Report for 2005. Indicates the condition of shoreline, determined by our staff of Coastal Engineers, for the year 2005. This...

  10. Environmental strategy

    DEFF Research Database (Denmark)

    Zabkar, Vesna; Cater, Tomaz; Bajde, Domen

    2013-01-01

    perspective, appropriate environmental strategies in compliance with environmental requirements aim at building competitive advantages through sustainable development. There is no universal “green” strategy that would be appropriate for each company, regardless of its market requirements and competitive......Environmental issues and the inclusion of environmental strategies in strategic thinking is an interesting subject of investigation. In general, managerial practices organized along ecologically sound principles contribute to a more environmentally sustainable global economy. From the managerial...

  11. Environmental management control. An empirical study on the use of environmental performance measures in management control systems

    NARCIS (Netherlands)

    Perego, P.M.

    2005-01-01

    Companies increasingly adapt their accounting systems to accommodate the internal demand of environmental-related information for making decisions and control their activities in compliance with extant environmental regulation. Prior research in environmental accounting has predominantly focused on

  12. Environmental exposures and gene regulation in disease etiology Exposição ambiental e regulação genética na etiologia de doenças

    Directory of Open Access Journals (Sweden)

    Thea M. Edwards

    2008-02-01

    Full Text Available Health or disease is shaped for all individuals by interactions between their genes and environment. Exactly how the environment changes gene expression and how this can lead to disease are being explored in a fruitful new approach to environmental health research, representative studies of which are reviewed here. We searched Web of Science and references of relevant publications to understand the diversity of gene regulatory mechanisms affected by environmental exposures with disease implications. Pharmaceuticals, pesticides, air pollutants, industrial chemicals, heavy metals, hormones, nutrition, and behavior can change gene expression through a broad array of gene regulatory mechanisms. Furthermore, chemically induced changes in gene regulation are associated with serious and complex human diseases, including cancer, diabetes and obesity, infertility, respiratory diseases, allergies, and neurodegenerative disorders such as Parkinson and Alzheimer diseases. The reviewed studies indicate that genetic predisposition for disease is best predicted in the context of environmental exposures. And the genetic mechanisms investigated in these studies offer new avenues for risk assessment research. Finally, we are likely to witness dramatic improvements in human health, and reductions in medical costs, if environmental pollution is decreased.Saúde e doença resultam da interação entre genes e o ambiente em que os indivíduos vivem. Vários estudos analisados neste artigo vêm explorando, com bons resultados, o modo como o ambiente modifica a expressão dos genes e como isso pode provocar doenças. Buscamos nas bases de dados científicas e referências de publicações relevantes, estudos que nos levaram a entender a diversidade de formas pelas quais os mecanismos regulatórios dos genes são afetados por exposições ambientais e implicam adoecimento. Medicamentos, pesticidas, poluentes do ar, produtos químicos, metais pesados, horm

  13. Renewable resource regulation and uncertain prices: The role of financial structure and bankruptcy

    International Nuclear Information System (INIS)

    Damania, Richard; Bulte, Erwin H.

    2006-01-01

    We analyze the interaction between regulatory policies and the financial structure of a fishery and show that firms with debts may respond differently to regulations than firms that have not accumulated debts. There are conditions where more stringent regulation is counterproductive, providing a perverse incentive to increase harvesting effort. We show that optimal regulation depends on the sector's financial structure, and demonstrate that there are cases when intervention is counterproductive, or too costly to implement. There are also cases where successful regulatory intervention can only be implemented when accompanied by a sufficiently large subsidy. (author)

  14. The CAMU Rule: A tool for implementing a protective, cost-effective remedy at the Fernald Environmental Management Project

    International Nuclear Information System (INIS)

    Dupuis-Nouille, E.M.; Goidell, L.C.; Strimbu, M.J.

    1995-01-01

    The Fernald Environmental Management Project (FEMP) is a former uranium processing facility currently under remediation pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act as amended (CERCLA). Contamination at the FEMP consists of low-level radioactivity, hazardous substances, hazardous wastes and/or mixed wastes. Regulations promulgated under the Resource Conservation and Recovery Act as amended (RCRA) are evaluated as applicable or relevant and appropriate requirements (ARARs) for remediation of the FEMP. Historically, joint CERCLA-RCRA guidance dictated that hazardous waste could not be treated, or moved out of the designated area of contiguous contamination (AOC), without triggering land disposal restrictions (LDRs) or minimum technology requirements (MTRs). To avoid invoking these stringent requirements, in situ capping was chosen as the lower cost remedy at many sites, although on-site disposal and/or treatment of hazardous wastes would have been more protective. The Corrective Action Management Units (CAMUs) and Temporary Units (TUs) Final Rule [58 FR 8658, Vol. 58, No. 29, hereinafter the open-quotes CAMU Ruleclose quotes], promulgated on February 16, 1993, provides facilities regulated under RCRA corrective action authority with greater flexibility to move, treat, and dispose of wastes on site without triggering LDRs or MTRs, thereby encouraging application of innovative technologies and more protective remedies. The waste acceptance criteria for the on-site disposal facility is based on site-specific considerations including the mobility of the contaminants through the underlying site geology and the protectiveness of the engineered liners. Application of the open-quotes CAMU Ruleclose quotes allows for disposition in the on-site facility based on these technical considerations rather than on regulatory classifications

  15. Environmental risk limits for zinc

    NARCIS (Netherlands)

    Bodar CWM; SEC

    2007-01-01

    Environmental Riks Limits (ERLs) were derived for zinc. ERLs serve as advisory values to set environmental quality standards in the Netherlands. The ERLs for zinc closely follow the outcomes of earlier discussions on zinc within the Water Framework Directive and EC Regulation 793/93. The ERLs refer

  16. Environmental risk limits for zinc

    NARCIS (Netherlands)

    Bodar CWM; SEC

    2007-01-01

    Environmental Riks Limits (ERLs) were derived for zinc. ERLs serve as advisory values to set environmental quality standards in the Netherlands. The ERLs for zinc closely follow the outcomes of earlier discussions on zinc within the Water Framework Directive and EC Regulation 793/93. The ERLs

  17. Environmental Requirements Management

    Energy Technology Data Exchange (ETDEWEB)

    Cusack, Laura J.; Bramson, Jeffrey E.; Archuleta, Jose A.; Frey, Jeffrey A.

    2015-01-08

    CH2M HILL Plateau Remediation Company (CH2M HILL) is the U.S. Department of Energy (DOE) prime contractor responsible for the environmental cleanup of the Hanford Site Central Plateau. As part of this responsibility, the CH2M HILL is faced with the task of complying with thousands of environmental requirements which originate from over 200 federal, state, and local laws and regulations, DOE Orders, waste management and effluent discharge permits, Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) response and Resource Conservation and Recovery Act (RCRA) corrective action documents, and official regulatory agency correspondence. The challenge is to manage this vast number of requirements to ensure they are appropriately and effectively integrated into CH2M HILL operations. Ensuring compliance with a large number of environmental requirements relies on an organization’s ability to identify, evaluate, communicate, and verify those requirements. To ensure that compliance is maintained, all changes need to be tracked. The CH2M HILL identified that the existing system used to manage environmental requirements was difficult to maintain and that improvements should be made to increase functionality. CH2M HILL established an environmental requirements management procedure and tools to assure that all environmental requirements are effectively and efficiently managed. Having a complete and accurate set of environmental requirements applicable to CH2M HILL operations will promote a more efficient approach to: • Communicating requirements • Planning work • Maintaining work controls • Maintaining compliance

  18. Trends in environmental management

    Energy Technology Data Exchange (ETDEWEB)

    Arnold, J.E. [Arthur D. Little of Canada Limited, Toronto, ON (Canada)

    1995-11-01

    Changes wrought by environmental regulations in the way companies produce, develop, and deliver their products and services were discussed. Some `tell-tale` signs of a vacuum of industry leadership in environmental affairs were identified. These included: lack of a `visible` corporate environmental policy, role confusion, limited action in response to plans, process myopia, poorly utilized data, hidden accomplishments, and an adversarial relationship with the regulatory bodies. Key trends in environmental management, and the necessary attributes for effective environmental management expected of the next generation of industry leaders were briefly described, including (1) the incorporation of environmental plans into the core of the business process, and into corporate strategy; (2) the formation of business-led, line-driven, rather than staff driven plans; and (3) increased measurement and broad dissemination of environmental successes, and their incorporation into the company`s strategic leverage. The overwhelming importance of commitment at the highest level, and the value of a business-oriented approach over a functional approach for effective environmental management were stressed.

  19. Magnetic fusion: Environmental Readiness Document

    International Nuclear Information System (INIS)

    1981-03-01

    Environmental Readiness Documents are prepared periodically to review and evaluate the environmental status of an energy technology during the several phases of development of that technology. Through these documents, the Office of Environment within the Department of Energy provides an independent and objective assessment of the environmental risks and potential impacts associated with the progression of the technology to the next stage of development and with future extensive use of the technology. This Environmental Readiness Document was prepared to assist the Department of Energy in evaluating the readiness of magnetic fusion technology with respect to environmental issues. An effort has been made to identify potential environmental problems that may be encountered based upon current knowledge, proposed and possible new environmental regulations, and the uncertainties inherent in planned environmental research

  20. Does environmental policy affect scaling laws between population and pollution? Evidence from American metropolitan areas.

    Science.gov (United States)

    Muller, Nicholas Z; Jha, Akshaya

    2017-01-01

    Modern cities are engines of production, innovation, and growth. However, urbanization also increases both local and global pollution from household consumption and firms' production. Do emissions change proportionately to city size or does pollution tend to outpace or lag urbanization? Do emissions scale differently with population versus economic growth or are emissions, population, and economic growth inextricably linked? How are the scaling relationships between emissions, population, and economic growth affected by environmental regulation? This paper examines the link between urbanization, economic growth and pollution using data from Metropolitan Statistical Areas (MSAs) in the United States between 1999 and 2011. We find that the emissions of local air pollution in these MSAs scale according to a ¾ power law with both population size and gross domestic product (GDP). However, the monetary damages from these local emissions scale linearly with both population and GDP. Counties that have previously been out of attainment with the local air quality standards set by the Clean Air Act show an entirely different relationship: local emissions scale according to the square root of population, while the monetary damages from local air pollution follow a 2/3rds power law with population. Counties out of attainment are subject to more stringent emission controls; we argue based on this that enforcement of the Clean Air Act induces sublinear scaling between emissions, damages, and city size. In contrast, we find that metropolitan GDP scales super-linearly with population in all MSAs regardless of attainment status. Summarizing, our findings suggest that environmental policy limits the adverse effects of urbanization without interfering with the productivity benefits that manifest in cities.