WorldWideScience

Sample records for strike-slip focal mechanisms

  1. Combining Earthquake Focal Mechanism Inversion and Coulomb Friction Law to Yield Tectonic Stress Magnitudes in Strike-slip Faulting Regime

    Science.gov (United States)

    Soh, I.; Chang, C.

    2017-12-01

    The techniques for estimating present-day stress states by inverting multiple earthquake focal mechanism solutions (FMS) provide orientations of the three principal stresses and their relative magnitudes. In order to estimate absolute magnitudes of the stresses that are generally required to analyze faulting mechanics, we combine the relative stress magnitude parameter (R-value) derived from the inversion process and the concept of frictional equilibrium of stress state defined by Coulomb friction law. The stress inversion in Korean Peninsula using 152 FMS data (magnitude≥2.5) conducted at regularly spaced grid points yields a consistent strike-slip faulting regime in which the maximum (S1) and the minimum (S3) principal stresses act in horizontal planes (with an S1 azimuth in ENE-WSW) and the intermediate principal stress (S2) close to vertical. However, R-value varies from 0.28 to 0.75 depending on locations, systematically increasing eastward. Based on the assumptions that the vertical stress is lithostatic, pore pressure is hydrostatic, and the maximum differential stress (S1-S3) is limited by Byerlee's friction of optimally oriented faults for slip, we estimate absolute magnitudes of the two horizontal principal stresses using R-value. As R-value increases, so do the magnitudes of the horizontal stresses. Our estimation of the stress magnitudes shows that the maximum horizontal principal stress (S1) normalized by vertical stress tends to increase from 1.3 in the west to 1.8 in the east. The estimated variation of stress magnitudes is compatible with distinct clustering of faulting types in different regions. Normal faulting events are densely populated in the west region where the horizontal stress is relatively low, whereas numerous reverse faulting events prevail in the east offshore where the horizontal stress is relatively high. Such a characteristic distribution of distinct faulting types in different regions can only be explained in terms of stress

  2. Shell Tectonics: A Mechanical Model for Strike-slip Displacement on Europa

    Science.gov (United States)

    Rhoden, Alyssa Rose; Wurman, Gilead; Huff, Eric M.; Manga, Michael; Hurford, Terry A.

    2012-01-01

    We introduce a new mechanical model for producing tidally-driven strike-slip displacement along preexisting faults on Europa, which we call shell tectonics. This model differs from previous models of strike-slip on icy satellites by incorporating a Coulomb failure criterion, approximating a viscoelastic rheology, determining the slip direction based on the gradient of the tidal shear stress rather than its sign, and quantitatively determining the net offset over many orbits. This model allows us to predict the direction of net displacement along faults and determine relative accumulation rate of displacement. To test the shell tectonics model, we generate global predictions of slip direction and compare them with the observed global pattern of strike-slip displacement on Europa in which left-lateral faults dominate far north of the equator, right-lateral faults dominate in the far south, and near-equatorial regions display a mixture of both types of faults. The shell tectonics model reproduces this global pattern. Incorporating a small obliquity into calculations of tidal stresses, which are used as inputs to the shell tectonics model, can also explain regional differences in strike-slip fault populations. We also discuss implications for fault azimuths, fault depth, and Europa's tectonic history.

  3. Active strike-slip faulting in El Salvador, Central America

    Science.gov (United States)

    Corti, Giacomo; Carminati, Eugenio; Mazzarini, Francesco; Oziel Garcia, Marvyn

    2005-12-01

    Several major earthquakes have affected El Salvador, Central America, during the Past 100 yr as a consequence of oblique subduction of the Cocos plate under the Caribbean plate, which is partitioned between trench-orthogonal compression and strike-slip deformation parallel to the volcanic arc. Focal mechanisms and the distribution of the most destructive earthquakes, together with geomorphologic evidence, suggest that this transcurrent component of motion may be accommodated by a major strike-slip fault (El Salvador fault zone). We present field geological, structural, and geomorphological data collected in central El Salvador that allow the constraint of the kinematics and the Quaternary activity of this major seismogenic strike-slip fault system. Data suggest that the El Salvador fault zone consists of at least two main ˜E-W fault segments (San Vicente and Berlin segments), with associated secondary synthetic (WNW-ESE) and antithetic (NNW-SSE) Riedel shears and NW-SE tensional structures. The two main fault segments overlap in a dextral en echelon style with the formation of an intervening pull-apart basin. Our original geological and geomorphologic data suggest a late Pleistocene Holocene slip rate of ˜11 mm/yr along the Berlin segment, in contrast with low historical seismicity. The kinematics and rates of deformation suggested by our new data are consistent with models involving slip partitioning during oblique subduction, and support the notion that a trench-parallel component of motion between the Caribbean and Cocos plates is concentrated along E-W dextral strike-slip faults parallel to the volcanic arc.

  4. The significance of strike-slip faulting in the basement of the Zagros fold and thrust belt

    Energy Technology Data Exchange (ETDEWEB)

    Hessami, K.; Koyi, H.A.; Talbot, C.J. [Uppsala University (Sweden). Institute of Earth Sciences

    2000-01-01

    Lateral offsets in the pattern of seismicity along the Zagros fold and thrust belt indicate that transverse faults segmenting the Arabian basement are active deep-seated strike-slip faults. The dominant NW-SE trending features of the belt have undergone repeated horizontal displacements along these transverse faults. These reactivated basement faults, which are inherited from the Pan-African construction phase, controlled both deposition of the Phanerozoic cover before Tertiary-Recent deformation of the Zagros and probably the entrapment of hydrocarbons on the NE margin of Arabia and in the Zagros area. We have used observations of faulting recognized on Landsat satellite images, in conjunction with the spatial distribution of earthquakes and their focal mechanism solutions, to infer a tectonic model for the Zagros basement. Deformation in the NW Zagros appears to be concentrated on basement thrusts and a few widely-spaced north-south trending strike-slip faults which separate major structural segments. In the SE Zagros, two main structural domains can be distinguished. A domain of NNW-trending right-lateral faults in the northern part of the SE Zagros implies that fault-bounded blocks are likely to have rotated anticlockwise about vertical axes relative to both Arabia and Central Iran. In contrast, the predominance of NNE-trending left-lateral faults in the southern part of the SE Zagros implies that fault-bounded blocks may have rotated clockwise about vertical axes. We propose a tectonic model in which crustal blocks bounded by strike-slip faults in a zone of simple shear rotate about vertical axes relative to both Arabia and Central Iran. The presence of domains of strike-slip and thrust faulting in the Zagros basement suggest that some of the convergence between Arabia and Central Iran is accommodated by rotation and possible lateral movement of crust along the belt by strike-slip faults, as well as by obvious crustal shortening and thickening along thrust

  5. Origin and structure of major orogen-scale exhumed strike-slip

    Science.gov (United States)

    Cao, Shuyun; Neubauer, Franz

    2016-04-01

    The formation of major exhumed strike-slip faults represents one of the most important dynamic processes affecting the evolution of the Earth's lithosphere and surface. Detailed models of the potential initiation and properties and architecture of orogen-scale exhumed strike-slip faults and how these relate to exhumation are rare. In this study, we deal with key properties controlling the development of major exhumed strike-slip fault systems, which are equivalent to the deep crustal sections of active across fault zones. We also propose two dominant processes for the initiation of orogen-scale exhumed strike-slip faults: (1) pluton-controlled and (2) metamorphic core complex-controlled strike-slip faults. In these tectonic settings, the initiation of faults occurs by rheological weakening along hot-to-cool contacts and guides the overall displacement and ultimate exhumation. These processes result in a specific thermal and structural architecture of such faults. These types of strike-slip dominated fault zones are often subparallel to mountain ranges and expose a wide variety of mylonitic, cataclastic and non-cohesive fault rocks, which were formed at different structural levels of the crust during various stages of faulting. The high variety of distinctive fault rocks is a potential evidence for recognition of these types of strike-slip faults. Exhumation of mylonitic rocks is, therefore, a common feature of such reverse oblique-slip strike-slip faults, implying major transtensive and/or transpressive processes accompanying pure strike-slip motion during exhumation. Some orogen-scale strike-slip faults nucleate and initiate along rheologically weak zones, e.g. at granite intrusions, zones of low-strength minerals, thermally weakened crust due to ascending fluids, and lateral borders of hot metamorphic core complexes. A further mechanism is the juxtaposition of mechanically strong mantle lithosphere to hot asthenosphere in continental transform faults (e.g., San

  6. Strike-slip tectonics during rift linkage

    Science.gov (United States)

    Pagli, C.; Yun, S. H.; Ebinger, C.; Keir, D.; Wang, H.

    2017-12-01

    The kinematics of triple junction linkage and the initiation of transforms in magmatic rifts remain debated. Strain patterns from the Afar triple junction provide tests of current models of how rifts grow to link in area of incipient oceanic spreading. Here we present a combined analysis of seismicity, InSAR and GPS derived strain rate maps to reveal that the plate boundary deformation in Afar is accommodated primarily by extensional tectonics in the Red Sea and Gulf of Aden rifts, and does not require large rotations about vertical axes (bookshelf faulting). Additionally, models of stress changes and seismicity induced by recent dykes in one sector of the Afar triple junction provide poor fit to the observed strike-slip earthquakes. Instead we explain these patterns as rift-perpendicular shearing at the tips of spreading rifts where extensional strains terminate against less stretched lithosphere. Our results demonstrate that rift-perpendicular strike-slip faulting between rift segments achieves plate boundary linkage during incipient seafloor spreading.

  7. The 2005 - 2007 Bala (Ankara, central Turkey) earthquakes: a case study for strike-slip fault terminations

    OpenAIRE

    Esat, K.; Çivgin, B.; Kaypak, B.; Isik, V.; Ecevitoglu, B.; Seyitoglu, G.

    2014-01-01

    An intense seismic activity has been observed after the Bala (Ankara, NW central Turkey) earthquakes (30 July 2005: Mw=5.3, 20 December 2007: Mw=5.4, and 26 December 2007: Mw=5.3), continuing up to the present. The epicenters and the focal mechanism solutions of the earthquakes indicate that the right lateral strike-slip Afşar fault, trending N55-60°W, is responsible for the main shocks. The Afşar fault is thought to be the NW continuation of the Tuzgölü fault zone, which is one of the main n...

  8. Onset of aseismic creep on major strike-slip faults

    KAUST Repository

    Ç akir, Ziyadin; Ergintav, Semih; Ö zener, Haluk; Doǧan, Uǧur; Akoglu, Ahmet; Meghraoui, Mustapha; Reilinger, Robert E.

    2012-01-01

    Time series analysis of spaceborne synthetic aperture radar (SAR) data, GPS measurements, and fi eld observations reveal that the central section of the Izmit (Turkey) fault that slipped with a supershear rupture velocity in the A.D. 1999, Mw7.4, Izmit earthquake began creeping aseismically following the earthquake. Rapid initial postseismic afterslip decayed logarithmically with time and appears to have reached a steady rate comparable to the preearthquake full fault-crossing rate, suggesting that it may continue for decades and possibly until late in the earthquake cycle. If confi rmed by future monitoring, these observations identify postseismic afterslip as a mechanism for initiating creep behavior along strike-slip faults. Long-term afterslip and/or creep has signifi cant implications for earthquake cycle models, recurrence intervals of large earthquakes, and accordingly, seismic hazard estimation along mature strike-slip faults, in particular for Istanbul which is believed to lie adjacent to a seismic gap along the North Anatolian fault in the Sea of Marmara. © 2012 Geological Society of America.

  9. Onset of aseismic creep on major strike-slip faults

    KAUST Repository

    Çakir, Ziyadin

    2012-10-02

    Time series analysis of spaceborne synthetic aperture radar (SAR) data, GPS measurements, and fi eld observations reveal that the central section of the Izmit (Turkey) fault that slipped with a supershear rupture velocity in the A.D. 1999, Mw7.4, Izmit earthquake began creeping aseismically following the earthquake. Rapid initial postseismic afterslip decayed logarithmically with time and appears to have reached a steady rate comparable to the preearthquake full fault-crossing rate, suggesting that it may continue for decades and possibly until late in the earthquake cycle. If confi rmed by future monitoring, these observations identify postseismic afterslip as a mechanism for initiating creep behavior along strike-slip faults. Long-term afterslip and/or creep has signifi cant implications for earthquake cycle models, recurrence intervals of large earthquakes, and accordingly, seismic hazard estimation along mature strike-slip faults, in particular for Istanbul which is believed to lie adjacent to a seismic gap along the North Anatolian fault in the Sea of Marmara. © 2012 Geological Society of America.

  10. Inferences about the local stress field from focal mechanisms: Applications to earthquakes in the southern Great Basin of Nevada

    International Nuclear Information System (INIS)

    Harmsen, S.C.; Rogers, A.M.

    1986-01-01

    Focal mechanisms determined from regional-network earthquake data or aftershock field investigation often contain members ranging from strike slip to normal slip in extensional tectonic environments or from strike slip to thrust slip in compressional environments. Although the coexistence of normal and strike-slip faulting has suggested to some investigators that the maximum and intermediate principal stresses are of approximately equal magnitude, several have asserted that the directions of principle stresses can or must interchange to accommodate both types of mechanisms (Zoback and Zoback 1980b; Vetter and Ryall, 1983). A Coulomb-Navier criterion of slip is invoked to demonstrate that both types of mechanisms, as well as oblique members having preferred nodal-plane dips intermediate between those of the strike-slip and normal mechanisms, may be observed in a region where the stress field, resolved into principal components, is axially symmetric. The proximate coexistence of earthquakes having diverse focal mechanisms could be interpreted as evidence for an approximately axially symmetric stress field in a region where optimally oriented planes of weakness are known to exist in the host rock. 10 refs., 6 figs

  11. What causes an icy fault to slip? Investigating strike-slip failure conditions on Ganymede at Dardanus and Tiamat Sulcus.

    Science.gov (United States)

    Cameron, M. E.; Smith-Konter, B. R.; Burkhard, L. M.; Collins, G. C.; Seifert, F.; Pappalardo, R. T.

    2015-12-01

    Ganymede exhibits two geologically distinct terrains known as dark and light (grooved) terrain. The mechanism for a transition from dark to light terrain remains unclear; however, inferences of strike-slip faulting and distributed shear zones suggest that strike-slip tectonism may be important to the structural development of Ganymede's surface and in this transition. Here we investigate the role of tidal stresses on Ganymede in the formation and evolution of strike-slip structures in both dark and grooved terrains. Using numerical code SatStress, we calculate both diurnal and non-synchronous rotation (NSR) tidal stresses at Ganymede's surface. Specifically, we investigate the role of fault friction and orbital eccentricity in the development of ~45 km of right-lateral offset at Dardanus Sulcus and a possible case of study with a detailed morphological mapping of strike-slip morphologies (en echelon structures, strike-slip duplexes, laterally offset pre-existing features, and possible strained craters) at Nun Sulcus and several other locations. These structures serve as example regions to provide improved constraints for global stress mechanisms responsible for strike-slip fault evolution on Ganymede.

  12. The 2012 Strike-slip Earthquake Sequence in Black Sea and its Link to the Caucasus Collision Zone

    Science.gov (United States)

    Tseng, T. L.; Hsu, C. H.; Legendre, C. P.; Jian, P. R.; Huang, B. S.; Karakhanian, A.; Chen, C. W.

    2016-12-01

    The Black Sea formed as a back-arc basin in Late Cretaceous to Paleogene with lots of extensional features. However, the Black Sea is now tectonically stable and absent of notable earthquakes except for the coastal region. In this study we invert regional waveforms of a new seismic array to constrain the focal mechanisms and depths of the 2012/12/23 earthquake sequence occurred in northeastern Black Sea basin that can provide unique estimates on the stress field in the region. The results show that the focal mechanisms for the main shock and 5 larger aftershocks are all strike-slip faulting and resembling with each other. The main rupture fall along the vertical dipping, NW-SE trending sinistral fault indicated by the lineation of most aftershocks. The fault strike and aftershock distribution are both consistent with the Shatsky Ridge, which is continental in nature but large normal faults was created by previous subsidence. The occurrence of 2012 earthquakes can be re-activated, as strike-slip, on one of the pre-existing normal fault cutting at depth nearly 20-30 km in the extended crust. Some of the aftershocks, including a larger one occurred 5 days later, are distributed toward NE direction 20 km away from main fault zone. Those events might be triggered by the main shock along a conjugate fault, which is surprisingly at the extension of proposed transform fault perpendicular to the rift axis of eastern Black Sea Basin. The focal mechanisms also indicate that the maximum compression in northeast Black Sea is at E-W direction, completely different from the N-S compression in the Caucasus and East Turkey controlled by Arabia-Eurasia collision. The origin of E-W maximum compression is probably the same as the secondary stress inferred from earthquakes in Racha region of the Greater Caucasus.

  13. FMC: a one-liner Python program to manage, classify and plot focal mechanisms

    Science.gov (United States)

    Álvarez-Gómez, José A.

    2014-05-01

    The analysis of earthquake focal mechanisms (or Seismic Moment Tensor, SMT) is a key tool on seismotectonics research. Each focal mechanism is characterized by several location parameters of the earthquake hypocenter, the earthquake size (magnitude and scalar moment tensor) and some geometrical characteristics of the rupture (nodal planes orientations, SMT components and/or SMT main axes orientations). The aim of FMC is to provide a simple but powerful tool to manage focal mechanism data. The data should be input to the program formatted as one of two of the focal mechanisms formatting options of the GMT (Generic Mapping Tools) package (Wessel and Smith, 1998): the Harvard CMT convention and the single nodal plane Aki and Richards (1980) convention. The former is a SMT format that can be downloaded directly from the Global CMT site (http://www.globalcmt.org/), while the later is the simplest way to describe earthquake rupture data. FMC is programmed in Python language, which is distributed as Open Source GPL-compatible, and therefore can be used to develop Free Software. Python runs on almost any machine, and has a wide support and presence in any operative system. The program has been conceived with the modularity and versatility of the classical UNIX-like tools. Is called from the command line and can be easily integrated into shell scripts (*NIX systems) or batch files (DOS/Windows systems). The program input and outputs can be done by means of ASCII files or using standard input (or redirection "") and pipes ("|"). By default FMC will read the input and write the output as a Harvard CMT (psmeca formatted) ASCII file, although other formats can be used. Optionally FMC will produce a classification diagram representing the rupture type of the focal mechanisms processed. In order to count with a detailed classification of the focal mechanisms I decided to classify the focal mechanism in a series of fields that include the oblique slip regimes. This approximation

  14. Assemblage of strike-slip faults and tectonic extension and ...

    Indian Academy of Sciences (India)

    12

    the formation, evolution and distribution of these strike-slip faults have important. 80 ...... function of coal-derived gas study for natural gas industry development in China; .... Bohai-Zhangjiakou seismotectonic zone based on 3D visco-elastic ...

  15. The rupture process of the Manjil, Iran earthquake of 20 june 1990 and implications for intraplate strike-slip earthquakes

    Science.gov (United States)

    Choy, G.L.; Zednik, J.

    1997-01-01

    In terms of seismically radiated energy or moment release, the earthquake of 20 January 1990 in the Manjil Basin-Alborz Mountain region of Iran is the second largest strike-slip earthquake to have occurred in an intracontinental setting in the past decade. It caused enormous loss of life and the virtual destruction of several cities. Despite a very large meizoseismal area, the identification of the causative faults has been hampered by the lack of reliable earthquake locations and conflicting field reports of surface displacement. Using broadband data from global networks of digitally recording seismographs, we analyse broadband seismic waveforms to derive characteristics of the rupture process. Complexities in waveforms generated by the earthquake indicate that the main shock consisted of a tiny precursory subevent followed in the next 20 seconds by a series of four major subevents with depths ranging from 10 to 15 km. The focal mechanisms of the major subevents, which are predominantly strike-slip, have a common nodal plane striking about 285??-295??. Based on the coincidence of this strike with the dominant tectonic fabric of the region we presume that the EW striking planes are the fault planes. The first major subevent nucleated slightly south of the initial precursor. The second subevent occurred northwest of the initial precursor. The last two subevents moved progressively southeastward of the first subevent in a direction collinear with the predominant strike of the fault planes. The offsets in the relative locations and the temporal delays of the rupture subevents indicate heterogeneous distribution of fracture strength and the involvement of multiple faults. The spatial distribution of teleseismic aftershocks, which at first appears uncorrelated with meizoseismal contours, can be decomposed into stages. The initial activity, being within and on the periphery of the rupture zone, correlates in shape and length with meizoseismal lines. In the second stage

  16. Rheological structure of the lithosphere in plate boundary strike-slip fault zones

    Science.gov (United States)

    Chatzaras, Vasileios; Tikoff, Basil; Kruckenberg, Seth C.; Newman, Julie; Titus, Sarah J.; Withers, Anthony C.; Drury, Martyn R.

    2016-04-01

    How well constrained is the rheological structure of the lithosphere in plate boundary strike-slip fault systems? Further, how do lithospheric layers, with rheologically distinct behaviors, interact within the strike-slip fault zones? To address these questions, we present rheological observations from the mantle sections of two lithospheric-scale, strike-slip fault zones. Xenoliths from ˜40 km depth (970-1100 ° C) beneath the San Andreas fault system (SAF) provide critical constraints on the mechanical stratification of the lithosphere in this continental transform fault. Samples from the Bogota Peninsula shear zone (BPSZ, New Caledonia), which is an exhumed oceanic transform fault, provide insights on lateral variations in mantle strength and viscosity across the fault zone at a depth corresponding to deformation temperatures of ˜900 ° C. Olivine recrystallized grain size piezometry suggests that the shear stress in the SAF upper mantle is 5-9 MPa and in the BPSZ is 4-10 MPa. Thus, the mantle strength in both fault zones is comparable to the crustal strength (˜10 MPa) of seismogenic strike-slip faults in the SAF system. Across the BPSZ, shear stress increases from 4 MPa in the surrounding rocks to 10 MPa in the mylonites, which comprise the core of the shear zone. Further, the BPSZ is characterized by at least one order of magnitude difference in the viscosity between the mylonites (1018 Paṡs) and the surrounding rocks (1019 Paṡs). Mantle viscosity in both the BPSZ mylonites and the SAF (7.0ṡ1018-3.1ṡ1020 Paṡs) is relatively low. To explain our observations from these two strike-slip fault zones, we propose the "lithospheric feedback" model in which the upper crust and lithospheric mantle act together as an integrated system. Mantle flow controls displacement and the upper crust controls the stress magnitude in the system. Our stress data combined with data that are now available for the middle and lower crustal sections of other transcurrent fault

  17. A recent Mw 4.3 earthquake proving activity of a shallow strike-slip fault in the northern part of the Western Desert, Egypt

    Science.gov (United States)

    Ezzelarab, Mohamed; Ebraheem, Mohamed O.; Zahradník, Jiří

    2018-03-01

    The Mw 4.3 earthquake of September 2015 is the first felt earthquake since 1900 A.D in the northern part of the Western Desert, Egypt, south of the El-Alamein City. The available waveform data observed at epicentral distances 52-391 km was collected and carefully evaluated. Nine broad-band stations were selected to invert full waveforms for the centroid position (horizontal and vertical) and for the focal mechanism solution. The first-arrival travel times, polarities and low-frequency full waveforms (0.03-0.08 Hz) are consistently explained in this paper as caused by a shallow source of the strike-slip mechanism. This finding indicates causal relation of this earthquake to the W-E trending South El-Alamein fault, which developed in Late Cretaceous as dextral strike slip fault. Recent activity of this fault, proven by the studied rare earthquake, is of fundamental importance for future seismic hazard evaluations, underlined by proximity (∼65 km) of the source zone to the first nuclear power plant planned site in Egypt. Safe exploration and possible future exploitation of hydrocarbon reserves, reported around El-Alamein fault in the last decade, cannot be made without considering the seismic potential of this fault.

  18. COMPARISON OF COSEISMIC IONOSPHERIC DISTURBANCE WAVEFORMS REVISITED: STRIKE-SLIP, NORMAL, AND REVERSE FAULT EARTHQUAKE

    Directory of Open Access Journals (Sweden)

    Mokhamad Nur Cahyadi

    2015-02-01

    Full Text Available Using Total Electron Content (TEC measurements with Global Positioning System we studied ionospheric responses to three large earthquakes with difference focal mechanism that occurred in the Sumatra Andaman 26 December 2004, North off Sumatra 11 April 2012, and North Japan 7 December 2012. These earthquakes have different focal mechanisms, i.e. high-angle reverse, strike-slip, and normal faulting, respectively. TEC responses to the Sumatra Andaman 2004 and north Japan 2012 events initiated with positive changes. On the other hand, the initial TEC changes in the Sumatra 2012 earthquake showed both positive and negative polarities depending on the azimuth around the focal area. Such a variety may reflect differences in coseismic vertical crustal displacements, which are dominated by uplift and subsidence in the Sumatra 2012 event. This phenomena has same characteristic with 1994 Kuril Arch earthquake. There are three different propagation velocity in the Sumatra 2012 earthquake, within the first 300 km until 430 km, the CID propagation velocity was ~3 km/s, which is equal to the secod sound speed at the height of the ionospheric F-layer. Starting from 380 km until 750 km out from the epicenter, the disturbance seems to divide into two separate perturbations, with each propagating at a different velocity, about 1 km/s for the one and about 0.4 m/s for the other. The apparent velocity in the Sumatra Andaman 2004 and Japan 2012 propagated ~ 1 km/s and ~ 0.3 km/s, consistent with the sound speed at the ionospheric F layer height and internal gravity wave respectively. Resonant oscillation of TEC with a frequency of ~ 3.7 mHZ and ~4.4 mHz have been found in the Sumatra 2012 and Sumatra Andaman 2004 events. Those earthquakes, which occurred during a period of quiet geomagnetic activity, also showed clear preseismic TEC anomalies similar to those before the 2011 Tohoku-Oki and 2007 Bengkulu earthquake.   The positive anomalies started 30-60 minutes

  19. Evidence of extensional and strike-slip deformation in the offshore Gökova-Kos area affected by the July 2017 Mw6.6 Bodrum-Kos earthquake, eastern Aegean Sea

    Science.gov (United States)

    Ocakoğlu, Neslihan; Nomikou, Paraskevi; İşcan, Yeliz; Loreto, Maria Filomena; Lampridou, Danai

    2018-01-01

    The interpretation of new multichannel seismic profiles and previously published high-resolution swath and seismic reflection data from the Gökova Gulf and southeast of Kos Island in the eastern Aegean Sea revealed new morphotectonic features related to the July 20, 2017 Mw6.6 Bodrum-Kos earthquake offshore between Kos Island and the Bodrum Peninsula. The seafloor morphology in the northern part of the gulf is characterized by south-dipping E-W-oriented listric normal faults. These faults bend to a ENE-WSW direction towards Kos Island, and then extend parallel to the southern coastline. A left-lateral SW-NE strike-slip fault zone is mapped with segments crossing the Gökova Gulf from its northern part to south of Kos Island. This fault zone intersects and displaces the deep basins in the gulf. The basins are thus interpreted as the youngest deformed features in the study area. The strike-slip faults also produce E-W-oriented ridges between the basin segments, and the ridge-related vertical faults are interpreted as reverse faults. This offshore study reveals that the normal and strike-slip faults are well correlated with the focal mechanism solutions of the recent earthquake and general seismicity of the Gökova Gulf. Although the complex morphotectonic features could suggest that the area is under a transtensional regime, kinematic elements normally associated with a transtensional system are missing. At present, the Gökova Gulf is experiencing strike-slip motion with dominant extensional deformation, rather than transtensional deformation.

  20. Evidence of extensional and strike-slip deformation in the offshore Gökova-Kos area affected by the July 2017 Mw6.6 Bodrum-Kos earthquake, eastern Aegean Sea

    Science.gov (United States)

    Ocakoğlu, Neslihan; Nomikou, Paraskevi; İşcan, Yeliz; Loreto, Maria Filomena; Lampridou, Danai

    2018-06-01

    The interpretation of new multichannel seismic profiles and previously published high-resolution swath and seismic reflection data from the Gökova Gulf and southeast of Kos Island in the eastern Aegean Sea revealed new morphotectonic features related to the July 20, 2017 Mw6.6 Bodrum-Kos earthquake offshore between Kos Island and the Bodrum Peninsula. The seafloor morphology in the northern part of the gulf is characterized by south-dipping E-W-oriented listric normal faults. These faults bend to a ENE-WSW direction towards Kos Island, and then extend parallel to the southern coastline. A left-lateral SW-NE strike-slip fault zone is mapped with segments crossing the Gökova Gulf from its northern part to south of Kos Island. This fault zone intersects and displaces the deep basins in the gulf. The basins are thus interpreted as the youngest deformed features in the study area. The strike-slip faults also produce E-W-oriented ridges between the basin segments, and the ridge-related vertical faults are interpreted as reverse faults. This offshore study reveals that the normal and strike-slip faults are well correlated with the focal mechanism solutions of the recent earthquake and general seismicity of the Gökova Gulf. Although the complex morphotectonic features could suggest that the area is under a transtensional regime, kinematic elements normally associated with a transtensional system are missing. At present, the Gökova Gulf is experiencing strike-slip motion with dominant extensional deformation, rather than transtensional deformation.

  1. Strike-Slip Fault Deformation and Its Control in Hydrocarbon Trapping in Ketaling Area, Jambi Subbasin, Indonesia

    Science.gov (United States)

    Ramadhan, Aldis; Badai Samudra, Alexis; Jaenudin; Puji Lestari, Enik; Saputro, Julian; Sugiono; Hirosiadi, Yosi; Amrullah, Indi

    2018-03-01

    Geologically, Ketaling area consists of a local high considered as flexure margin of Tempino-Kenali Asam Deep in west part and graben in east part also known as East Ketaling Deep. Numerous proven plays were established in Ketaling area with reservoir in early Miocene carbonate and middle Miocene sand. This area underwent several major deformations. Faults are developed widely, yet their geometrical features and mechanisms of formation remained so far indistinct, which limited exploration activities. With new three-dimensional seismic data acquired in 2014, this area evidently interpreted as having strike-slip mechanism. The objective of this study is to examine characteristic of strike slip fault and its affect to hydrocarbon trapping in Ketaling Area. Structural pattern and characteristic of strike slip fault deformation was examined with integration of normal seismic with variance seismic attribute analysis and the mapping of Syn-rift to Post-rift horizon. Seismic flattening on 2D seismic cross section with NW-SE direction is done to see the structural pattern related to horst (paleohigh) and graben. Typical flower structure, branching strike-slip fault system and normal fault in synrift sediment clearly showed in section. An echelon pattern identified from map view as the result of strike slip mechanism. Detail structural geology analysis show the normal fault development which has main border fault in the southern of Ketaling area dipping to the Southeast-East with NE-SW lineament. These faults related to rift system in Ketaling area. NW-SE folds with reactive NE-SW fault which act as hydrocarbon trapping in the shallow zone. This polyphase tectonic formed local graben, horst and inverted structure developed a good kitchen area (graben) and traps (horst, inverted structure). Subsequently, hydrocarbon accumulation potentials such as basement fractures, inverted syn-rift deposit and shallow zone are very interesting to explore in this area.

  2. Magma storage in a strike-slip caldera.

    Science.gov (United States)

    Saxby, J; Gottsmann, J; Cashman, K; Gutiérrez, E

    2016-07-22

    Silicic calderas form during explosive volcanic eruptions when magma withdrawal triggers collapse along bounding faults. The nature of specific interactions between magmatism and tectonism in caldera-forming systems is, however, unclear. Regional stress patterns may control the location and geometry of magma reservoirs, which in turn may control the spatial and temporal development of faults. Here we provide new insight into strike-slip volcano-tectonic relations by analysing Bouguer gravity data from Ilopango caldera, El Salvador, which has a long history of catastrophic explosive eruptions. The observed low gravity beneath the caldera is aligned along the principal horizontal stress orientations of the El Salvador Fault Zone. Data inversion shows that the causative low-density structure extends to ca. 6 km depth, which we interpret as a shallow plumbing system comprising a fractured hydrothermal reservoir overlying a magmatic reservoir with vol% exsolved vapour. Fault-controlled localization of magma constrains potential vent locations for future eruptions.

  3. The 2014 Mw6.9 Gokceada and 2017 Mw6.3 Lesvos Earthquakes in the Northern Aegean Sea: The Transition from Right-Lateral Strike-Slip Faulting on the North Anatolian Fault to Extension in the Central Aegean

    Science.gov (United States)

    Cetin, S.; Konca, A. O.; Dogan, U.; Floyd, M.; Karabulut, H.; Ergintav, S.; Ganas, A.; Paradisis, D.; King, R. W.; Reilinger, R. E.

    2017-12-01

    The 2014 Mw6.9 Gokceada (strike-slip) and 2017 Mw6.3 Lesvos (normal) earthquakes represent two of the set of faults that accommodate the transition from right-lateral strike-slip faulting on the North Anatolian Fault (NAF) to normal faulting along the Gulf of Corinth. The Gokceada earthquake was a purely strike-slip event on the western extension of the NAF where it enters the northern Aegean Sea. The Lesvos earthquake, located roughly 200 km south of Gokceada, occurred on a WNW-ESE-striking normal fault. Both earthquakes respond to the same regional stress field, as indicated by their sub-parallel seismic tension axis and far-field coseismic GPS displacements. Interpretation of GPS-derived velocities, active faults, crustal seismicity, and earthquake focal mechanisms in the northern Aegean indicates that this pattern of complementary faulting, involving WNW-ESE-striking normal faults (e.g. Lesvos earthquake) and SW-NE-striking strike-slip faults (e.g. Gokceada earthquake), persists across the full extent of the northern Aegean Sea. The combination of these two "families" of faults, combined with some systems of conjugate left-lateral strike-slip faults, complement one another and culminate in the purely extensional rift structures that form the large Gulfs of Evvia and Corinth. In addition to being consistent with seismic and geodetic observations, these fault geometries explain the increasing velocity of the southern Aegean and Peloponnese regions towards the Hellenic subduction zone. Alignment of geodetic extension and seismic tension axes with motion of the southern Aegean towards the Hellenic subduction zone suggests a direct association of Aegean extension with subduction, possibly by trench retreat, as has been suggested by prior investigators.

  4. Strike-slip pull-apart process and emplacement of Xiangshan uranium-producing volcanic basin

    International Nuclear Information System (INIS)

    Qiu Aijin; Guo Lingzhi; Shu Liangshu

    2001-01-01

    Xiangshan volcanic basin is one of the famous uranium-producing volcanic basins in China. Emplacement mechanism of Xiangshan uranium-producing volcanic basin is discussed on the basis of the latest research achievements of deep geology in Xiangshan area and the theory of continental dynamics. The study shows that volcanic activity in Xiangshan volcanic basin may be divided into two cycles, and its emplacement is controlled by strike-ship pull-apart process originated from the deep regional faults. Volcanic apparatus in the first cycle was emplaced in EW-trending structure activated by clockwise strike-slipping of NE-trending deep fault, forming the EW-trending fissure-type volcanic effusion belt. Volcanic apparatus in the second cycle was emplaced at junction points of SN-trending pull-apart structure activated by sinistral strike-slipping of NE-trending deep faults and EW-trending basement faults causing the center-type volcanic magma effusion and extrusion. Moreover, the formation mechanism of large-rich uranium deposits is discussed as well

  5. Earthquake focal mechanism forecasting in Italy for PSHA purposes

    Science.gov (United States)

    Roselli, Pamela; Marzocchi, Warner; Mariucci, Maria Teresa; Montone, Paola

    2018-01-01

    In this paper, we put forward a procedure that aims to forecast focal mechanism of future earthquakes. One of the primary uses of such forecasts is in probabilistic seismic hazard analysis (PSHA); in fact, aiming at reducing the epistemic uncertainty, most of the newer ground motion prediction equations consider, besides the seismicity rates, the forecast of the focal mechanism of the next large earthquakes as input data. The data set used to this purpose is relative to focal mechanisms taken from the latest stress map release for Italy containing 392 well-constrained solutions of events, from 1908 to 2015, with Mw ≥ 4 and depths from 0 down to 40 km. The data set considers polarity focal mechanism solutions until to 1975 (23 events), whereas for 1976-2015, it takes into account only the Centroid Moment Tensor (CMT)-like earthquake focal solutions for data homogeneity. The forecasting model is rooted in the Total Weighted Moment Tensor concept that weighs information of past focal mechanisms evenly distributed in space, according to their distance from the spatial cells and magnitude. Specifically, for each cell of a regular 0.1° × 0.1° spatial grid, the model estimates the probability to observe a normal, reverse, or strike-slip fault plane solution for the next large earthquakes, the expected moment tensor and the related maximum horizontal stress orientation. These results will be available for the new PSHA model for Italy under development. Finally, to evaluate the reliability of the forecasts, we test them with an independent data set that consists of some of the strongest earthquakes with Mw ≥ 3.9 occurred during 2016 in different Italian tectonic provinces.

  6. Finite element models of earthquake cycles in mature strike-slip fault zones

    Science.gov (United States)

    Lynch, John Charles

    The research presented in this dissertation is on the subject of strike-slip earthquakes and the stresses that build and release in the Earth's crust during earthquake cycles. Numerical models of these cycles in a layered elastic/viscoelastic crust are produced using the finite element method. A fault that alternately sticks and slips poses a particularly challenging problem for numerical implementation, and a new contact element dubbed the "Velcro" element was developed to address this problem (Appendix A). Additionally, the finite element code used in this study was bench-marked against analytical solutions for some simplified problems (Chapter 2), and the resolving power was tested for the fault region of the models (Appendix B). With the modeling method thus developed, there are two main questions posed. First, in Chapter 3, the effect of a finite-width shear zone is considered. By defining a viscoelastic shear zone beneath a periodically slipping fault, it is found that shear stress concentrates at the edges of the shear zone and thus causes the stress tensor to rotate into non-Andersonian orientations. Several methods are used to examine the stress patterns, including the plunge angles of the principal stresses and a new method that plots the stress tensor in a manner analogous to seismic focal mechanism diagrams. In Chapter 4, a simple San Andreas-like model is constructed, consisting of two great earthquake producing faults separated by a freely-slipping shorter fault. The model inputs of lower crustal viscosity, fault separation distance, and relative breaking strengths are examined for their effect on fault communication. It is found that with a lower crustal viscosity of 1018 Pa s (in the lower range of estimates for California), the two faults tend to synchronize their earthquake cycles, even in the cases where the faults have asymmetric breaking strengths. These models imply that postseismic stress transfer over hundreds of kilometers may play a

  7. Focal mechanism of the seismic series prior to the 2011 El Hierro eruption

    Science.gov (United States)

    del Fresno, C.; Buforn, E.; Cesca, S.; Domínguez Cerdeña, I.

    2015-12-01

    The onset of the submarine eruption of El Hierro (10-Oct-2011) was preceded by three months of low-magnitude seismicity (Mw3.5). Amplitude spectra was fitted at local distances (<20km). Reliability and stability of the results were evaluated with synthetic data. Results show a change in the focal mechanism pattern within the first days of October, varying from complex sources of higher non-double-couple components before that date to a simpler strike-slip mechanism with horizontal tension axes on E-W direction the week prior to the eruption onset. A detailed study was carried out for the 8 October 2011 earthquake (Mw=4.0). Focal mechanism was retrieved using a MT inversion at regional and local distances. Results indicate an important component of strike-slip fault and null isotropic component. The stress pattern obtained corresponds to horizontal compression in a NNW-SSE direction, parallel to the southern ridge of the island, and a quasi-horizontal extension in an EW direction. Finally, a simple source time function of 0.3s has been estimated for this shock using the Empirical Green function methodology.

  8. San Andreas-sized Strike-slip Fault on Europa

    Science.gov (United States)

    1998-01-01

    This mosaic of the south polar region of Jupiter's moon Europa shows the northern 290 kilometers (180 miles) of a strike-slip fault named Astypalaea Linea. The entire fault is about 810 kilometers (500 miles) long, about the size of the California portion of the San Andreas fault, which runs from the California-Mexico border north to the San Francisco Bay. In a strike-slip fault, two crustal blocks move horizontally past one another, similar to two opposing lanes of traffic. Overall motion along the fault seems to have followed a continuous narrow crack along the feature's entire length, with a path resembling steps on a staircase crossing zones that have been pulled apart. The images show that about 50 kilometers (30 miles) of displacement have taken place along the fault. The fault's opposite sides can be reconstructed like a puzzle, matching the shape of the sides and older, individual cracks and ridges broken by its movements. [figure removed for brevity, see original site] The red line marks the once active central crack of the fault. The black line outlines the fault zone, including material accumulated in the regions which have been pulled apart. Bends in the fault have allowed the surface to be pulled apart. This process created openings through which warmer, softer ice from below Europa's brittle ice shell surface, or frozen water from a possible subsurface ocean, could reach the surface. This upwelling of material formed large areas of new ice within the boundaries of the original fault. A similar pulling-apart phenomenon can be observed in the geological trough surrounding California's Salton Sea, in Death Valley and the Dead Sea. In those cases, the pulled-apart regions can include upwelled materials, but may be filled mostly by sedimentary and eroded material from above. One theory is that fault motion on Europa is induced by the pull of variable daily tides generated by Jupiter's gravitational tug on Europa. Tidal tension opens the fault and

  9. Stress regimes in the northwest of Iran from stress inversion of earthquake focal mechanisms

    Science.gov (United States)

    Afra, Mahsa; Moradi, Ali; Pakzad, Mehrdad

    2017-11-01

    Northwestern Iran is one of the seismically active regions with a high seismic risk in the world. This area is a part of the complex tectonic system due to the interaction between Arabia, Anatolia and Eurasia. The purpose of this study is to deduce the stress regimes in the northwestern Iran and surrounding regions from stress inversion of earthquake focal mechanisms. We compile 92 focal mechanisms data from the Global CMT catalogue and other sources and also determine the focal mechanisms of 14 earthquakes applying the moment tensor inversion. We divide the studied region into 9 zones using similarity of the horizontal GPS velocities and existing focal mechanisms. We implement two stress inversion methods, Multiple Inverse Method and Iterative Joint Inversion Method, which provide comparable results in terms of orientations of maximum horizontal stress axes SHmax. The similar results of the two methods should make us more confident about the interpretations. We consider zones of exclusion surrounding all the earthquakes according to independent focal mechanisms hypothesis. The hypothesis says that the inversion should involve events that are far enough from each other in order that any previous event doesn't affect the stress field near the earthquake under consideration. Accordingly we deal with the matter by considering zones of exclusion around all the events. The result of exclusion is only significant for eastern Anatolia. The stress regime in this region changes from oblique to strike slip faulting because of the exclusion. In eastern Anatolia, the direction of maximum horizontal stress is nearly north-south. The direction alters to east-west in Talesh region. Errors of σ1 are lower in all zones comparing with errors of σ2 and σ3 and there is a trade-off between data resolution and covariance of the model. The results substantiate the strike-slip and thrust faulting stress regimes in the northwest of Iran.

  10. Geometry and kinematics of adhesive wear in brittle strike-slip fault zones

    Science.gov (United States)

    Swanson, Mark T.

    2005-05-01

    Detailed outcrop surface mapping in Late Paleozoic cataclastic strike-slip faults of coastal Maine shows that asymmetric sidewall ripouts, 0.1-200 m in length, are a significant component of many mapped faults and an important wall rock deformation mechanism during faulting. The geometry of these structures ranges from simple lenses to elongate slabs cut out of the sidewalls of strike-slip faults by a lateral jump of the active zone of slip during adhesion along a section of the main fault. The new irregular trace of the active fault after this jump creates an indenting asperity that is forced to plow through the adjoining wall rock during continued adhesion or be cut off by renewed motion along the main section of the fault. Ripout translation during adhesion sets up the structural asymmetry with trailing extensional and leading contractional ends to the ripout block. The inactive section of the main fault trace at the trailing end can develop a 'sag' or 'half-graben' type geometry due to block movement along the scallop-shaped connecting ramp to the flanking ripout fault. Leading contractional ramps can develop 'thrust' type imbrication and forces the 'humpback' geometry to the ripout slab due to distortion of the inactive main fault surface by ripout translation. Similar asymmetric ripout geometries are recognized in many other major crustal scale strike-slip fault zones worldwide. Ripout structures in the 5-500 km length range can be found on the Atacama fault system of northern Chile, the Qujiang and Xiaojiang fault zones in western China, the Yalakom-Hozameen fault zone in British Columbia and the San Andreas fault system in southern California. For active crustal-scale faults the surface expression of ripout translation includes a coupled system of extensional trailing ramps as normal oblique-slip faults with pull-apart basin sedimentation and contractional leading ramps as oblique thrust or high angle reverse faults with associated uplift and erosion. The

  11. Strike-slip faults offshore southern Taiwan: implications for the oblique arc-continent collision processes

    Science.gov (United States)

    Fuh, Shi-Chie; Liu, Char-Shine; Lundberg, Neil; Reed, Donald L.

    1997-06-01

    Taiwan is the site of present-day oblique arc-continent collision between the Luzon arc of the Philippine Sea plate and the Chinese continental margin. The major structural pattern revealed from marine geophysical studies in the area offshore southern Taiwan is that of a doubly-vergent orogenic belt, bounded by significant zones of thrusting on the west and east of the submarine accretionary wedge. Due to the oblique collision process, strike-slip faults could play an important role in this convergent domain. Topographic lineaments revealed from new digital bathymetry data and seismic reflection profiles confirm the existence of three sets of strike-slip faults in the collision-subduction zone offshore southern Taiwan: the N-S-trending left-lateral strike-slip faults within the Luzon volcanic arc, the NE-SW-trending right-lateral strike-slip faults across the accretionary wedge, and the NNE-SSW-trending left-lateral strike-slip faults lie in the frontal portion of the accretionary wedge. These strike-slip faults overprint pre-existing folds and thrusts and may convert into oblique thrusts or thrusts as the forearc blocks accrete to the mountain belt. A bookshelf rotation model is used to explain the observed geometrical relationships of these strike-slip fault systems. Based on this model, the counter-clockwise rotation of the forearc blocks in the area offshore southern Taiwan could have caused extrusion of the accretionary wedge material into the forearc basin. The originally continuous forearc basin is thus deformed into several closed and separate proto-collisional basins such as the Southern Longitudinal Trough and Taitung Trough. A tectonic evolution model which emphasizes on the development of various structures at different stages of the oblique arc-continent collision for the Taiwan mountain belt is proposed.

  12. Earthquake focal mechanisms and stress orientations in the eastern Swiss Alps

    International Nuclear Information System (INIS)

    Marschall, I.; Deichmann, N.; Marone, F.

    2013-01-01

    This study presents an updated set of earthquake focal mechanisms in the Helvetic and Penninic/Austroalpine domains of the eastern Swiss Alps. In eight cases, based on high-precision relative hypocentre locations of events within individual earthquake sequences, it was possible to identify the active fault plane. Whereas the focal mechanisms in the Helvetic domain are mostly strike-slip, the Penninic/Austroalpine domain is dominated by normal-faulting mechanisms. Given this systematic difference in faulting style, an inversion for the stress field was performed separately for the two regions. The stress field in the Penninic/Austroalpine domain is characterized by extension oriented obliquely to the E-W strike of the orogen. Hence, the Penninic nappes, which were emplaced as large-scale compressional structures during the Alpine orogenesis, are now deforming in an extensional mode. This contrasts with the more compressional strike-slip regime in the Helvetic domain towards the northern Alpine front. Relative to the regional stress field seen in the northern Alpine foreland with a NNW-SSE compression and an ENE-WSW extension, the orientation of the least compressive stress in the Penninic/Austroalpine domain is rotated counter-clockwise by about 40 °C. Following earlier studies, the observed rotation of the orientation of the least compressive stress in the Penninic/Austroalpine region can be explained as the superposition of the regional stress field of the northern foreland and a uniaxial extensional stress perpendicular to the local trend of the Alpine mountain belt. (authors)

  13. Analysis of the growth of strike-slip faults using effective medium theory

    Energy Technology Data Exchange (ETDEWEB)

    Aydin, A.; Berryman, J.G.

    2009-10-15

    Increases in the dimensions of strike-slip faults including fault length, thickness of fault rock and the surrounding damage zone collectively provide quantitative definition of fault growth and are commonly measured in terms of the maximum fault slip. The field observations indicate that a common mechanism for fault growth in the brittle upper crust is fault lengthening by linkage and coalescence of neighboring fault segments or strands, and fault rock-zone widening into highly fractured inner damage zone via cataclastic deformation. The most important underlying mechanical reason in both cases is prior weakening of the rocks surrounding a fault's core and between neighboring fault segments by faulting-related fractures. In this paper, using field observations together with effective medium models, we analyze the reduction in the effective elastic properties of rock in terms of density of the fault-related brittle fractures and fracture intersection angles controlled primarily by the splay angles. Fracture densities or equivalent fracture spacing values corresponding to the vanishing Young's, shear, and quasi-pure shear moduli were obtained by extrapolation from the calculated range of these parameters. The fracture densities or the equivalent spacing values obtained using this method compare well with the field data measured along scan lines across the faults in the study area. These findings should be helpful for a better understanding of the fracture density/spacing distribution around faults and the transition from discrete fracturing to cataclastic deformation associated with fault growth and the related instabilities.

  14. The Trans-Rocky Mountain Fault System - A Fundamental Precambrian Strike-Slip System

    Science.gov (United States)

    Sims, P.K.

    2009-01-01

    Recognition of a major Precambrian continental-scale, two-stage conjugate strike-slip fault system - here designated as the Trans-Rocky Mountain fault system - provides new insights into the architecture of the North American continent. The fault system consists chiefly of steep linear to curvilinear, en echelon, braided and branching ductile-brittle shears and faults, and local coeval en echelon folds of northwest strike, that cut indiscriminately across both Proterozoic and Archean cratonic elements. The fault system formed during late stages of two distinct tectonic episodes: Neoarchean and Paleoproterozoic orogenies at about 2.70 and 1.70 billion years (Ga). In the Archean Superior province, the fault system formed (about 2.70-2.65 Ga) during a late stage of the main deformation that involved oblique shortening (dextral transpression) across the region and progressed from crystal-plastic to ductile-brittle deformation. In Paleoproterozoic terranes, the fault system formed about 1.70 Ga, shortly following amalgamation of Paleoproterozoic and Archean terranes and the main Paleoproterozoic plastic-fabric-producing events in the protocontinent, chiefly during sinistral transpression. The postulated driving force for the fault system is subcontinental mantle deformation, the bottom-driven deformation of previous investigators. This model, based on seismic anisotropy, invokes mechanical coupling and subsequent shear between the lithosphere and the asthenosphere such that a major driving force for plate motion is deep-mantle flow.

  15. High tsunami frequency as a result of combined strike-slip faulting and coastal landslides

    Science.gov (United States)

    Hornbach, Matthew J.; Braudy, Nicole; Briggs, Richard W.; Cormier, Marie-Helene; Davis, Marcy B.; Diebold, John B.; Dieudonne, Nicole; Douilly, Roby; Frohlich, Cliff; Gulick, Sean P.S.; Johnson, Harold E.; Mann, Paul; McHugh, Cecilia; Ryan-Mishkin, Katherine; Prentice, Carol S.; Seeber, Leonardo; Sorlien, Christopher C.; Steckler, Michael S.; Symithe, Steeve Julien; Taylor, Frederick W.; Templeton, John

    2010-01-01

    Earthquakes on strike-slip faults can produce devastating natural hazards. However, because they consist predominantly of lateral motion, these faults are rarely associated with significant uplift or tsunami generation. And although submarine slides can generate tsunami, only a few per cent of all tsunami are believed to be triggered in this way. The 12 January Mw 7.0 Haiti earthquake exhibited primarily strike-slip motion but nevertheless generated a tsunami. Here we present data from a comprehensive field survey that covered the onshore and offshore area around the epicentre to document that modest uplift together with slope failure caused tsunamigenesis. Submarine landslides caused the most severe tsunami locally. Our analysis suggests that slide-generated tsunami occur an order-of-magnitude more frequently along the Gonave microplate than global estimates predict. Uplift was generated because of the earthquake's location, where the Caribbean and Gonave microplates collide obliquely. The earthquake also caused liquefaction at several river deltas that prograde rapidly and are prone to failure. We conclude that coastal strike-slip fault systems such as the Enriquillo-Plantain Garden fault produce relief conducive to rapid sedimentation, erosion and slope failure, so that even modest predominantly strike-slip earthquakes can cause potentially catastrophic slide-generated tsunami - a risk that is underestimated at present.

  16. Strike-slip deformation reflects complex partitioning of strain in the Nankai Accretionary Prism (SE Japan)

    Science.gov (United States)

    Azevedo, Marco C.; Alves, Tiago M.; Fonseca, Paulo E.; Moore, Gregory F.

    2018-01-01

    Previous studies have suggested predominant extensional tectonics acting, at present, on the Nankai Accretionary Prism (NAP), and following a parallel direction to the convergence vector between the Philippine Sea and Amur Plates. However, a complex set of thrusts, pop-up structures, thrust anticlines and strike-slip faults is observed on seismic data in the outer wedge of the NAP, hinting at a complex strain distribution across SE Japan. Three-dimensional (3D) seismic data reveal three main families of faults: (1) NE-trending thrusts and back-thrusts; (2) NNW- to N-trending left-lateral strike-slip faults; and (3) WNW-trending to E-W right-lateral strike-slip faults. Such a fault pattern suggests that lateral slip, together with thrusting, are the two major styles of deformation operating in the outer wedge of the NAP. Both styles of deformation reflect a transpressional tectonic regime in which the maximum horizontal stress is geometrically close to the convergence vector. This work is relevant because it shows a progressive change from faults trending perpendicularly to the convergence vector, to a broader partitioning of strain in the form of thrusts and conjugate strike-slip faults. We suggest that similar families of faults exist within the inner wedge of the NAP, below the Kumano Basin, and control stress accumulation and strain accommodation in this latter region.

  17. A note on 2-D lithospheric deformation due to a blind strike-slip fault

    Indian Academy of Sciences (India)

    mic deformation. Several researchers have devel- oped models of coseismic lithospheric deformation. Rybicki (1971) found a closed-form analytical solu- tion for the problem of a long vertical strike-slip fault in a two-layer model of the earth. Chinnery and Jovanovich (1972) extended the solution to a three-layer model.

  18. Carpathian Shear Corridor – A strike-slip boundary of an extruded crustal segment

    Czech Academy of Sciences Publication Activity Database

    Marko, F.; Andriessen, P.A.M.; Tomek, Č.; Bezák, V.; Fojtíková, Lucia; Bošanský, M.; Piovarči, M.; Reichenwalder, P.

    703-704, APR 22 (2017), s. 119-134 ISSN 0040-1951 Grant - others:Slovak Foundation Grant(SK) VEGA 2/0188/15 Institutional support: RVO:67985891 Keywords : extrusion * Neo-alpine evolution * strike-slip faulting * uplift history * Western Carpathians Subject RIV: DC - Siesmology, Volcanology, Earth Structure OBOR OECD: Geology Impact factor: 2.693, year: 2016

  19. The Role of Near-Fault Relief in Creating and Maintaining Strike-Slip Landscape Features

    Science.gov (United States)

    Harbert, S.; Duvall, A. R.; Tucker, G. E.

    2016-12-01

    Geomorphic landforms, such as shutter ridges, offset river terraces, and deflected stream channels, are often used to assess the activity and slip rates of strike-slip faults. However, in some systems, such as parts of the Marlborough Fault System (South Island, NZ), an active strike-slip fault does not leave a strong landscape signature. Here we explore the factors that dampen or enhance the landscape signature of strike-slip faulting using the Channel-Hillslope Integrated Landscape Development model (CHILD). We focus on variables affecting the length of channel offsets, which enhance the signature of strike-slip motion, and the frequency of stream captures, which eliminate offsets and reduce this signature. We model a strike-slip fault that passes through a mountain ridge, offsetting streams that drain across this fault. We use this setup to test the response of channel offset length and capture frequency to fault characteristics, such as slip rate and ratio of lateral to vertical motion, and to landscape characteristics, such as relief contrasts controlled by erodibility. Our experiments show that relief downhill of the fault, whether generated by differential uplift across the fault or by an erodibility contrast, has the strongest effect on offset length and capture frequency. This relief creates shutter ridges, which block and divert streams while being advected along a fault. Shutter ridges and the streams they divert have long been recognized as markers of strike-slip motion. Our results show specifically that the height of shutter ridges is most responsible for the degree to which they create long channel offsets by preventing stream captures. We compare these results to landscape metrics in the Marlborough Fault System, where shutter ridges are common and often lithologically controlled. We compare shutter ridge length and height to channel offset length in order to assess the influence of relief on offset channel features in a real landscape. Based on our

  20. Strike slip faulting inferred from offsetting of drainages: Lower ...

    Indian Academy of Sciences (India)

    Two levels of fluvial terraces have developed along the ... (a) Two levels of alluvial terraces abutting against the .... source mechanics; (eds) Das J, Boatwright J, Scholz C H, ... tectonics and alluvial rivers; Cambridge University Press. NY, 276 ...

  1. Strike-slip tectonics and Quaternary basin formation along the Vienna Basin fault system inferred from Bouguer gravity derivatives

    NARCIS (Netherlands)

    Salcher, B. C.; Meurers, B.; Smit, J.; Decker, K.; HöLzel, M.; Wagreich, M.

    2012-01-01

    The Vienna Basin at the transition between the Alpine and Carpathian belt hosts a number of large Pleistocene sub-basins forming along an active continental scale strike-slip fault (Vienna Basin strike-slip fault). We utilize first-order derivatives from industrial Bouguer gravity data to unravel

  2. Long term fault system reorganization of convergent and strike-slip systems

    Science.gov (United States)

    Cooke, M. L.; McBeck, J.; Hatem, A. E.; Toeneboehn, K.; Beyer, J. L.

    2017-12-01

    Laboratory and numerical experiments representing deformation over many earthquake cycles demonstrate that fault evolution includes episodes of fault reorganization that optimize work on the fault system. Consequently, the mechanical and kinematic efficiencies of fault systems do not increase monotonically through their evolution. New fault configurations can optimize the external work required to accommodate deformation, suggesting that changes in system efficiency can drive fault reorganization. Laboratory evidence and numerical results show that fault reorganization within accretion, strike-slip and oblique convergent systems is associated with increasing efficiency due to increased fault slip (frictional work and seismic energy) and commensurate decreased off-fault deformation (internal work and work against gravity). Between episodes of fault reorganization, fault systems may become less efficient as they produce increasing off fault deformation. For example, laboratory and numerical experiments show that the interference and interaction between different fault segments may increase local internal work or that increasing convergence can increase work against gravity produced by a fault system. This accumulation of work triggers fault reorganization as stored work provides the energy required to grow new faults that reorganize the system to a more efficient configuration. The results of laboratory and numerical experiments reveal that we should expect crustal fault systems to reorganize following periods of increasing inefficiency, even in the absence of changes to the tectonic regime. In other words, fault reorganization doesn't require a change in tectonic loading. The time frame of fault reorganization depends on fault system configuration, strain rate and processes that relax stresses within the crust. For example, stress relaxation may keep pace with stress accumulation, which would limit the increase in the internal work and gravitational work so that

  3. The cenozoic strike-slip faults and TTHE regional crust stability of Beishan area

    International Nuclear Information System (INIS)

    Guo Zhaojie; Zhang Zhicheng; Zhang Chen; Liu Chang; Zhang Yu; Wang Ju; Chen Weiming

    2008-01-01

    The remote sensing images and geological features of Beishan area indicate that the Altyn Tagh fault, Sanweishan-Shuangta fault, Daquan fault and Hongliuhe fault are distributed in Beishan area from south to north. The faults are all left-lateral strike-slip faults with trending of NE40-50°, displaying similar distribution pattern. The secondary branch faults are developed at the end of each main strike-slip fault with nearly east to west trending form dendritic oblique crossings at the angle of 30-50°. Because of the left-lateral slip of the branch faults, the granites or the blocks exposed within the branch faults rotate clockwisely, forming 'Domino' structures. So the structural style of Beishan area consists of the Altyn Tagh fault, Sanweishan-Shuangta fault, Daquan fault, Hongliuhe fault and their branch faults and rotational structures between different faults. Sedimentary analysis on the fault valleys in the study area and ESR chronological test of fault clay exhibit that the Sanweishan-Shuangta fault form in the late Pliocene (N2), while the Daquan fault displays formation age of l.5-1.2 Ma, and the activity age of the relevant branch faults is Late Pleistocene (400 ka). The ages become younger from the Altyn Tagh fault to the Daquan fault and strike-slip faults display NW trending extension, further revealing the lateral growth process of the strike-slip boundary at the northern margin during the Cenozoic uplift of Tibetan Plateau. The displacement amounts on several secondary faults caused by the activities of the faults are slight due to the above-mentioned structural distribution characteristics of Beishan area, which means that this area is the most stable active area with few seismic activities. We propose the main granitic bodies in Beishan area could be favorable preselected locations for China's high level radioactive waste repository. (authors)

  4. A note on 2-D lithospheric deformation due to a blind strike-slip fault

    Indian Academy of Sciences (India)

    Analytical solution for the problem of a surface-breaking long strike-slip fault in an elastic layer overlying an elastic half-space is well known. The purpose of this note is to obtain the corresponding solution for a blind fault. Since the solution is valid for arbitrary values of the fault-depth and the dip angle, the effects of these ...

  5. The morphology of strike-slip faults - Examples from the San Andreas Fault, California

    Science.gov (United States)

    Bilham, Roger; King, Geoffrey

    1989-01-01

    The dilatational strains associated with vertical faults embedded in a horizontal plate are examined in the framework of fault kinematics and simple displacement boundary conditions. Using boundary element methods, a sequence of examples of dilatational strain fields associated with commonly occurring strike-slip fault zone features (bends, offsets, finite rupture lengths, and nonuniform slip distributions) is derived. The combinations of these strain fields are then used to examine the Parkfield region of the San Andreas fault system in central California.

  6. Evolution of strike-slip fault systems and associated geomorphic structures. Model test

    International Nuclear Information System (INIS)

    Ueta, Keichi

    2003-01-01

    Sandbox experiments were performed to investigate evolution of fault systems and its associated geomorphic structures caused by strike-slip motion on basement faults. A 200 cm long, 40 cm wide, 25 cm high sandbox was used in a strike-slip fault model test. Computerized X-ray tomography applied to the sandbox experiments made it possible to analyze the kinematic evaluation, as well as the three-dimensional geometry, of the faults. The deformation of the sand pack surface was analyzed by use of a laser method 3D scanner, which is a three-dimensional noncontact surface profiling instrument. A comparison of the experimental results with natural cases of active faults reveals the following: In the left-lateral strike-slip fault experiments, the deformation of the sand pack with increasing basement displacement is observed as follows. 1) In three dimensions, the right-stepping shears that have a cirque'/'shell'/'shipbody' shape develop on both sides of the basement fault. The shears on one side of the basement fault join those on the other side, resulting in helicoidal shaped shear surfaces. Shears reach the surface of the sand near or above the basement fault and en echelon Riedel shears are observed at the surface of the sand. The region between two Riedels is always an up-squeezed block. 2) lower-angle shears generally branch off from the first Riedel shears. 3) Pressure ridges develop within the zone defined by the right-stepping helicoidal shaped lower-angle shears. 4) Grabens develop between the pressure ridges. 5) Y-shears offset the pressure ridges. 6) With displacement concentrated on the central throughgoing fault zone, a liner trough developed directly above the basement fault. R1 shear and P foliation are observed in the liner trough. Such evolution of the shears and its associated structures in the fault model tests agrees well with that of strike-slip fault systems and its associated geomorphic structures. (author)

  7. Characterization of Aftershock Sequences from Large Strike-Slip Earthquakes Along Geometrically Complex Faults

    Science.gov (United States)

    Sexton, E.; Thomas, A.; Delbridge, B. G.

    2017-12-01

    Large earthquakes often exhibit complex slip distributions and occur along non-planar fault geometries, resulting in variable stress changes throughout the region of the fault hosting aftershocks. To better discern the role of geometric discontinuities on aftershock sequences, we compare areas of enhanced and reduced Coulomb failure stress and mean stress for systematic differences in the time dependence and productivity of these aftershock sequences. In strike-slip faults, releasing structures, including stepovers and bends, experience an increase in both Coulomb failure stress and mean stress during an earthquake, promoting fluid diffusion into the region and further failure. Conversely, Coulomb failure stress and mean stress decrease in restraining bends and stepovers in strike-slip faults, and fluids diffuse away from these areas, discouraging failure. We examine spatial differences in seismicity patterns along structurally complex strike-slip faults which have hosted large earthquakes, such as the 1992 Mw 7.3 Landers, the 2010 Mw 7.2 El-Mayor Cucapah, the 2014 Mw 6.0 South Napa, and the 2016 Mw 7.0 Kumamoto events. We characterize the behavior of these aftershock sequences with the Epidemic Type Aftershock-Sequence Model (ETAS). In this statistical model, the total occurrence rate of aftershocks induced by an earthquake is λ(t) = λ_0 + \\sum_{i:t_i

  8. Tectonic stress orientations and magnitudes, and friction of faults, deduced from earthquake focal mechanism inversions over the Korean Peninsula

    Science.gov (United States)

    Soh, Inho; Chang, Chandong; Lee, Junhyung; Hong, Tae-Kyung; Park, Eui-Seob

    2018-05-01

    We characterize the present-day stress state in and around the Korean Peninsula using formal inversions of earthquake focal mechanisms. Two different methods are used to select preferred fault planes in the double-couple focal mechanism solutions: one that minimizes average misfit angle and the other choosing faults with higher instability. We invert selected sets of fault planes for estimating the principal stresses at regularly spaced grid points, using a circular-area data-binning method, where the bin radius is optimized to yield the best possible stress inversion results based on the World Stress Map quality ranking scheme. The inversions using the two methods yield well constrained and fairly comparable results, which indicate that the prevailing stress regime is strike-slip, and the maximum horizontal principal stress (SHmax) is oriented ENE-WSW throughout the study region. Although the orientation of the stresses is consistent across the peninsula, the relative stress magnitude parameter (R-value) varies significantly, from 0.22 in the northwest to 0.89 in the southeast. Based on our knowledge of the R-values and stress regime, and using a value for vertical stress (Sv) estimated from the overburden weight of rock, together with a value for the maximum differential stress (based on the Coulomb friction of faults optimally oriented for slip), we estimate the magnitudes of the two horizontal principal stresses. The horizontal stress magnitudes increase from west to east such that SHmax/Sv ratio rises from 1.5 to 2.4, and the Shmin/Sv ratio from 0.6 to 0.8. The variation in the magnitudes of the tectonic stresses appears to be related to differences in the rigidity of crustal rocks. Using the complete stress tensors, including both orientations and magnitudes, we assess the possible ranges of frictional coefficients for different types of faults. We show that normal and reverse faults have lower frictional coefficients than strike-slip faults, suggesting that

  9. Fault structure and kinematics of the Long Valley Caldera region, California, revealed by high-accuracy earthquake hypocenters and focal mechanism stress inversions

    Science.gov (United States)

    Prejean, Stephanie; Ellsworth, William L.; Zoback, Mark; Waldhauser, Felix

    2002-01-01

    We have determined high-resolution hypocenters for 45,000+ earthquakes that occurred between 1980 and 2000 in the Long Valley caldera area using a double-difference earthquake location algorithm and routinely determined arrival times. The locations reveal numerous discrete fault planes in the southern caldera and adjacent Sierra Nevada block (SNB). Intracaldera faults include a series of east/west-striking right-lateral strike-slip faults beneath the caldera's south moat and a series of more northerly striking strike-slip/normal faults beneath the caldera's resurgent dome. Seismicity in the SNB south of the caldera is confined to a crustal block bounded on the west by an east-dipping oblique normal fault and on the east by the Hilton Creek fault. Two NE-striking left-lateral strike-slip faults are responsible for most seismicity within this block. To understand better the stresses driving seismicity, we performed stress inversions using focal mechanisms with 50 or more first motions. This analysis reveals that the least principal stress direction systematically rotates across the studied region, from NE to SW in the caldera's south moat to WNW-ESE in Round Valley, 25 km to the SE. Because WNW-ESE extension is characteristic of the western boundary of the Basin and Range province, caldera area stresses appear to be locally perturbed. This stress perturbation does not seem to result from magma chamber inflation but may be related to the significant (???20 km) left step in the locus of extension along the Sierra Nevada/Basin and Range province boundary. This implies that regional-scale tectonic processes are driving seismic deformation in the Long Valley caldera.

  10. Magmatic control along a strike-slip volcanic arc: The central Aeolian arc (Italy)

    Science.gov (United States)

    Ruch, J.; Vezzoli, L.; De Rosa, R.; Di Lorenzo, R.; Acocella, V.

    2016-02-01

    The regional stress field in volcanic areas may be overprinted by that produced by magmatic activity, promoting volcanism and faulting. In particular, in strike-slip settings, the definition of the relationships between the regional stress field and magmatic activity remains elusive. To better understand these relationships, we collected stratigraphic, volcanic, and structural field data along the strike-slip central Aeolian arc (Italy): here the islands of Lipari and Vulcano separate the extensional portion of the arc (to the east) from the contractional one (to the west). We collected >500 measurements of faults, extension fractures, and dikes at 40 sites. Most structures are NNE-SSW to NNW-SSE oriented, eastward dipping, and show almost pure dip-slip motion, consistent with an E-W extension direction, with minor dextral and sinistral shear. Our data highlight six eruptive periods during the last 55 ka, which allow considering both islands as a single magmatic system, in which tectonic and magmatic activities steadily migrated eastward and currently focus on a 10 km long × 2 km wide active segment. Faulting appears to mostly occur in temporal and spatial relation with magmatic events, supporting that most of the observable deformation derives from transient magmatic activity (shorter term, days to months), rather than from steady longer-term regional tectonics (102-104 years). More in general, the central Aeolian case shows how magmatic activity may affect the structure and evolution of volcanic arcs, overprinting any strike-slip motion with magma-induced extension at the surface.

  11. Magmatic control along a strike-slip volcanic arc: The central Aeolian arc (Italy)

    KAUST Repository

    Ruch, Joel

    2016-01-23

    The regional stress field in volcanic areas may be overprinted by that produced by magmatic activity, promoting volcanism and faulting. In particular, in strike-slip settings, the definition of the relationships between the regional stress field and magmatic activity remains elusive. To better understand these relationships, we collected stratigraphic, volcanic and structural field data along the strike-slip Central Aeolian arc (Italy): here the islands of Lipari and Vulcano separate the extensional portion of the arc (to the east) from the contractional one (to the west). We collected >500 measurements of faults, extension fractures and dikes at 40 sites. Most structures are NNE-SSW to NNW-SSE oriented, eastward dipping, and show almost pure dip-slip motion; consistent with an E-W extension direction, with minor dextral and sinistral shear. Our data highlight six eruptive periods during the last 55 ka, which allow considering both islands as a single magmatic system, in which tectonic and magmatic activity steadily migrated eastward and currently focus on a 10 km long x 2 km wide active segment. Faulting appears to mostly occur in temporal and spatial relation with magmatic events, supporting that most of the observable deformation derives from transient magmatic activity (shorter-term, days to months), rather than from steady longer-term regional tectonics (102-104 years). More in general, the Central Aeolian case shows how magmatic activity may affect the structure and evolution of volcanic arcs, overprinting any strike-slip motion with magma-induced extension at the surface.

  12. Non-Andersonian conjugate strike-slip faults: Observations, theory, and tectonic implications

    International Nuclear Information System (INIS)

    Yin, A; Taylor, M H

    2008-01-01

    Formation of conjugate strike-slip faults is commonly explained by the Anderson fault theory, which predicts a X-shaped conjugate fault pattern with an intersection angle of ∼30 degrees between the maximum compressive stress and the faults. However, major conjugate faults in Cenozoic collisional orogens, such as the eastern Alps, western Mongolia, eastern Turkey, northern Iran, northeastern Afghanistan, and central Tibet, contradict the theory in that the conjugate faults exhibit a V-shaped geometry with intersection angles of 60-75 degrees, which is 30-45 degrees greater than that predicted by the Anderson fault theory. In Tibet and Mongolia, geologic observations can rule out bookshelf faulting, distributed deformation, and temporal changes in stress state as explanations for the abnormal fault patterns. Instead, the GPS-determined velocity field across the conjugate fault zones indicate that the fault formation may have been related to Hagen-Poiseuille flow in map view involving the upper crust and possibly the whole lithosphere based on upper mantle seismicity in southern Tibet and basaltic volcanism in Mongolia. Such flow is associated with two coeval and parallel shear zones having opposite shear sense; each shear zone produce a set of Riedel shears, respectively, and together the Riedel shears exhibit the observed non-Andersonian conjugate strike-slip fault pattern. We speculate that the Hagen-Poiseuille flow across the lithosphere that hosts the conjugate strike-slip zones was produced by basal shear traction related to asthenospheric flow, which moves parallel and away from the indented segment of the collisional fronts. The inferred asthenospheric flow pattern below the conjugate strike-slip fault zones is consistent with the magnitude and orientations of seismic anisotropy observed across the Tibetan and Mongolian conjugate fault zones, suggesting a strong coupling between lithospheric deformation and asthenospheric flow. The laterally moving

  13. Non-Andersonian conjugate strike-slip faults: Observations, theory, and tectonic implications

    Energy Technology Data Exchange (ETDEWEB)

    Yin, A [Department of Earth and Space Sciences and Institute of Geophysics and Planetary Physics, University of California, Los Angeles, Los Angeles, CA 90025-1567 (United States); Taylor, M H [Department of Geology, University of Kansas, 1475 Jayhawk Blvd., Lawrence, KS 66044 (United States)], E-mail: yin@ess.ucla.edu

    2008-07-01

    Formation of conjugate strike-slip faults is commonly explained by the Anderson fault theory, which predicts a X-shaped conjugate fault pattern with an intersection angle of {approx}30 degrees between the maximum compressive stress and the faults. However, major conjugate faults in Cenozoic collisional orogens, such as the eastern Alps, western Mongolia, eastern Turkey, northern Iran, northeastern Afghanistan, and central Tibet, contradict the theory in that the conjugate faults exhibit a V-shaped geometry with intersection angles of 60-75 degrees, which is 30-45 degrees greater than that predicted by the Anderson fault theory. In Tibet and Mongolia, geologic observations can rule out bookshelf faulting, distributed deformation, and temporal changes in stress state as explanations for the abnormal fault patterns. Instead, the GPS-determined velocity field across the conjugate fault zones indicate that the fault formation may have been related to Hagen-Poiseuille flow in map view involving the upper crust and possibly the whole lithosphere based on upper mantle seismicity in southern Tibet and basaltic volcanism in Mongolia. Such flow is associated with two coeval and parallel shear zones having opposite shear sense; each shear zone produce a set of Riedel shears, respectively, and together the Riedel shears exhibit the observed non-Andersonian conjugate strike-slip fault pattern. We speculate that the Hagen-Poiseuille flow across the lithosphere that hosts the conjugate strike-slip zones was produced by basal shear traction related to asthenospheric flow, which moves parallel and away from the indented segment of the collisional fronts. The inferred asthenospheric flow pattern below the conjugate strike-slip fault zones is consistent with the magnitude and orientations of seismic anisotropy observed across the Tibetan and Mongolian conjugate fault zones, suggesting a strong coupling between lithospheric deformation and asthenospheric flow. The laterally moving

  14. Source study of the Jan Mayen transform fault strike-slip earthquakes

    Science.gov (United States)

    Rodríguez-Pérez, Q.; Ottemöller, L.

    2014-07-01

    Seismic source parameters of oceanic transform zone earthquakes have been relatively poorly studied. Previous studies showed that this type of earthquakes has unique characteristics such as not only the relatively common occurrence of slow events with weak seismic radiation at high frequencies but also the occurrence of some events that have high apparent stress indicating strong high frequency radiation. We studied 5 strike-slip earthquakes in the Jan Mayen fracture zone with magnitudes in the range of 5.9 centroid time delay compared to other oceanic transform fault earthquakes.

  15. Crimea-Kopet Dagh zone of concentrated orogenic deformations as a transregional late collisional right-lateral strike-slip fault

    Science.gov (United States)

    Patina, I. S.; Leonov, Yu. G.; Volozh, Yu. A.; Kopp, M. L.; Antipov, M. P.

    2017-07-01

    It is shown that the Crimea, Caucasus, and Kopet Dagh fold systems make up a single whole unified by a lithospheric strike-slip fault zone of concentrated dislocations. The strike-slip fault that dissects the sedimentary cover and consolidated crust is rooted in subcrustal layers of the mantle. The notions about strike-slip dislocations in the structure of the Crimea-Kopet Dagh System are considered. Comparative analysis of structure, age, and amplitude of strike-slip fault segments is carried out. The effect of strike-slip faulting on the deep-seated and near-surface structure of the Earth's crust is considered. Based on estimation of strike-slip offsets, the paleogeography of Paleogene basins is refined; their initial contours, which have been disturbed and fragmented by slipping motion strike-slip displacement, have been reconstructed.

  16. A Study of Interactions Between Thrust and Strike-slip Faults

    Directory of Open Access Journals (Sweden)

    Jeng-Cheng Wang

    2013-01-01

    Full Text Available A 3-D finite difference method is applied in this study to investigate a spontaneous rupture within a fault system which includes a primary thrust fault and two strike-slip sub-faults. With the occurrence of a rupture on a fault, the rupture condition follows Coulomb¡¦s friction law wherein the stress-slip obeys the slip-weakening fracture criteria. To overcome the geometrical complexity of such a system, a finite difference method is encoded in two different coordinate systems; then, the calculated displacements are connected between the two systems using a 2-D interpolation technique. The rupture is initiated at the center of the main fault under the compression of regional tectonic stresses and then propagates to the boundaries whereby the main fault rupture triggers two strike-slip sub-faults. Simulation results suggest that the triggering of two sub-faults is attributed to two primary factors, regional tectonic stresses and the relative distances between the two sub-faults and the main fault.

  17. Evolution of the stress fields in the Zagros Foreland Folded Belt using focal mechanisms and kinematic analyses: the case of the Fars salient, Iran

    Science.gov (United States)

    Sarkarinejad, Khalil; Zafarmand, Bahareh; Oveisi, Behnam

    2018-03-01

    The NW-SE trending Zagros orogenic belt was initiated during the convergence of the Afro-Arabian continent and the Iranian microcontinent in the Late Cretaceous. Ongoing convergence is confirmed by intense seismicity related to compressional stresses collision-related in the Zagros orogenic belt by reactivation of an early extensional faulting to latter compressional segmented strike-slip and dip-slip faulting. These activities are strongly related either to the deep-seated basement fault activities (deep-seated earthquakes) underlies the sedimentary cover or gently dipping shallow-seated décollement horizon of the rheological weak rocks of the infra-Cambrian Hormuz salt. The compressional stress regimes in the different units play an important role in controlling the stress conditions between the different units within the sedimentary cover and basement. A significant set of nearly N-S trending right-lateral strike-slip faults exists throughout the study area in the Fars area in the Zagros Foreland Folded Belt. Fault-slip and focal mechanism data were analyzed using the stress inversion method to reconstruct the paleo and recent stress conditions. The results suggest that the current direction of maximum principal stress averages N19°E, with N38°E that for the past from Cretaceous to Tertiary (although a few sites on the Kar-e-Bass fault yield a different direction). The results are consistent with the collision of the Afro-Arabian continent and the Iranian microcontinent. The difference between the current and paleo-stress directions indicates an anticlockwise rotation in the maximum principle stress direction over time. This difference resulted from changes in the continental convergence path, but was also influenced by the local structural evolution, including the lateral propagation of folds and the presence of several local décollement horizons that facilitated decoupling of the deformation between the basement and the sedimentary cover. The obliquity of

  18. Tsunamis from strike-slip earthquakes in the Wharton Basin, northeast Indian Ocean: March 2016 Mw7.8 event and its relationship with the April 2012 Mw 8.6 event

    Science.gov (United States)

    Heidarzadeh, Mohammad; Harada, Tomoya; Satake, Kenji; Ishibe, Takeo; Takagawa, Tomohiro

    2017-12-01

    The Wharton Basin, off southwest Sumatra, ruptured to a large intraplate left-lateral strike-slip Mw 7.8 earthquake on 2016 March 2. The epicentre was located ∼800 km to the south of another similar-mechanism intraplate Mw 8.6 earthquake in the same basin on 2012 April 11. Small tsunamis from these strike-slip earthquakes were registered with maximum amplitudes of 0.5-1.5 cm on DARTs and 1-19 cm on tide gauges for the 2016 event, and the respective values of 0.5-6 and 6-40 cm for the 2012 event. By using both teleseismic body waves and tsunami observations of the 2016 event, we obtained optimum slip models with rupture velocity (Vr) in the range of 2.8-3.6 km s-1 belonging to both EW and NS faults. While the EW fault plane cannot be fully ruled out, we chose the best model as the NS fault plane with a Vr of 3.6 km s-1, a maximum slip of 7.7 m and source duration of 33 s. The tsunami energy period bands were 4-15 and 7-24 min for the 2016 and 2012 tsunamis, respectively, reflecting the difference in source sizes. Seismicity in the Wharton Basin is dominated by large strike-slip events including the 2012 (Mw 8.6 and 8.2) and 2016 (Mw 7.8) events, indicating that these events are possible tsunami sources in the Wharton Basin. Cumulative number and cumulative seismic-moment curves revealed that most earthquakes are of strike-slip mechanisms and the largest seismic-moment is provided by the strike-slip earthquakes in this basin.

  19. The role of post-collisional strike-slip tectonics in the geological evolution of the late Neoproterozoic volcano-sedimentary Guaratubinha Basin, southern Brazil

    Science.gov (United States)

    Barão, Leonardo M.; Trzaskos, Barbara; Vesely, Fernando F.; de Castro, Luís Gustavo; Ferreira, Francisco J. F.; Vasconcellos, Eleonora M. G.; Barbosa, Tiago C.

    2017-12-01

    The Guaratubinha Basin is a late Neoproterozoic volcano-sedimentary basin included in the transitional-stage basins of the South American Platform. The aim of this study is to investigate its tectonic evolution through a detailed structural analysis based on remote sensing and field data. The structural and aerogeophysics data indicate that at least three major deformational events affected the basin. Event E1 caused the activation of the two main basin-bounding fault zones, the Guaratubinha Master Fault and the Guaricana Shear Zone. These structures, oriented N20-45E, are associated with well-defined right-lateral to oblique vertical faults, conjugate normal faults and vertical flow structures. Progressive transtensional deformation along the two main fault systems was the main mechanism for basin formation and the deposition of thick coarse-grained deposits close to basin-borders. The continuous opening of the basin provided intense intermediate and acid magmatism as well as deposition of volcaniclastic sediments. Event E2 characterizes generalized compression, recorded as minor thrust faults with tectonic transport toward the northwest and left-lateral activation of the NNE-SSW Palmital Shear Zone. Event E3 is related to the Mesozoic tectonism associated with the South Atlantic opening, which generated diabase dykes and predominantly right-lateral strike-slip faults oriented N10-50W. Its rhomboidal geometry with long axis parallel to major Precambrian shear zones, the main presence of high-angle, strike-slip or oblique faults, the asymmetric distribution of geological units and field evidence for concomitant Neoproterozoic magmatism and strike-slip movements are consistent with pull-apart basins reported in the literature.

  20. Tectonics earthquake distribution pattern analysis based focal mechanisms (Case study Sulawesi Island, 1993–2012)

    International Nuclear Information System (INIS)

    Ismullah M, Muh. Fawzy; Lantu,; Aswad, Sabrianto; Massinai, Muh. Altin

    2015-01-01

    Indonesia is the meeting zone between three world main plates: Eurasian Plate, Pacific Plate, and Indo – Australia Plate. Therefore, Indonesia has a high seismicity degree. Sulawesi is one of whose high seismicity level. The earthquake centre lies in fault zone so the earthquake data gives tectonic visualization in a certain place. This research purpose is to identify Sulawesi tectonic model by using earthquake data from 1993 to 2012. Data used in this research is the earthquake data which consist of: the origin time, the epicenter coordinate, the depth, the magnitude and the fault parameter (strike, dip and slip). The result of research shows that there are a lot of active structures as a reason of the earthquake in Sulawesi. The active structures are Walannae Fault, Lawanopo Fault, Matano Fault, Palu – Koro Fault, Batui Fault and Moluccas Sea Double Subduction. The focal mechanism also shows that Walannae Fault, Batui Fault and Moluccas Sea Double Subduction are kind of reverse fault. While Lawanopo Fault, Matano Fault and Palu – Koro Fault are kind of strike slip fault

  1. Tectonics earthquake distribution pattern analysis based focal mechanisms (Case study Sulawesi Island, 1993–2012)

    Energy Technology Data Exchange (ETDEWEB)

    Ismullah M, Muh. Fawzy, E-mail: mallaniung@gmail.com [Master Program Geophysical Engineering, Faculty of Mining and Petroleum Engineering (FTTM), Bandung Institute of Technology (ITB), Jl. Ganesha no. 10, Bandung, 40116, Jawa Barat (Indonesia); Lantu,; Aswad, Sabrianto; Massinai, Muh. Altin [Geophysics Program Study, Faculty of Mathematics and Natural Sciences, Hasanuddin University (UNHAS), Jl. PerintisKemerdekaan Km. 10, Makassar, 90245, Sulawesi Selatan (Indonesia)

    2015-04-24

    Indonesia is the meeting zone between three world main plates: Eurasian Plate, Pacific Plate, and Indo – Australia Plate. Therefore, Indonesia has a high seismicity degree. Sulawesi is one of whose high seismicity level. The earthquake centre lies in fault zone so the earthquake data gives tectonic visualization in a certain place. This research purpose is to identify Sulawesi tectonic model by using earthquake data from 1993 to 2012. Data used in this research is the earthquake data which consist of: the origin time, the epicenter coordinate, the depth, the magnitude and the fault parameter (strike, dip and slip). The result of research shows that there are a lot of active structures as a reason of the earthquake in Sulawesi. The active structures are Walannae Fault, Lawanopo Fault, Matano Fault, Palu – Koro Fault, Batui Fault and Moluccas Sea Double Subduction. The focal mechanism also shows that Walannae Fault, Batui Fault and Moluccas Sea Double Subduction are kind of reverse fault. While Lawanopo Fault, Matano Fault and Palu – Koro Fault are kind of strike slip fault.

  2. A Possible Differentially Shortened Strike-slip Plate Boundary: the Okhotsk Plate Example.

    Science.gov (United States)

    Hindle, D.; Egorov, V.; Mackey, K. G.; Fujita, K.

    2004-12-01

    The Okhotsk plate has been postulated based on a combination of GPS geodetic inversions (REVEL1), seimsicity, geologic and lineament data. Lying between the North American and Eurasian plates, its northwestern corner would appear to be undergoing compression in a scissors motion between the two bounding plates. Extrusion tectonics along multiple, large strike-slip faults within the Okhotsk plate itself have been suggested to allow the escape of material away from the apex of Eurasia-North America. The plate boundary between Okhotsk and North America has been suggested to be diffuse, based on widely scattered minor seismicity. However, the large, left lateral, Ulakhan fault has also been suggested as a candidate plate boundary. We present field geological and geomorphological evidence of the partitioning of deformation between the Ulakhan fault, and several parallel and oblique, linked faults. The Ulakhan fault strand appears to have a maximum displacement of 24 km based on river valley offsets and closing large pull apart basins. Some of the displacement from the Ulakhan fault appears relayed into the plate margin along oblique trending, thrust/oblique slip faults. Estimated shortening over these faults is equivalent to the amount of shortening relayed into the plate margin from the plate boundary. There may be several thrust/oblique slip faults along the Ulakhan fault, which leads to the interesting situation of a segmented, strike-slip plate boundary being actively shortened in a margin parallel direction. This may be the result of postulated extrusion of the Okhotsk plate due to North America/Eurasia convergence. Such a situation would have important consequences for the interpretation of GPS data in a plate tectonic context.

  3. Seismicity, focal mechanisms, and stress distribution in the Tres Virgenes volcanic and geothermal region, Baja California Sur, Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Wong, Victor; Munguia, Luis [Centro de Investigacion Cientifica y de Educacion Superior de Ensenada (Mexico)

    2006-01-15

    In October 1993 we carried out a seismic monitoring in the Tres Virgenes volcanic region in order to record the background seismicity associated with the volcanic structures, the geothermal field and the tectonic features of the area. Hypocenters for 257 microearthquakes were located in the volcanic edifices and along the northwest right-lateral, strike-slip La Virgen fault. Focal depths range from close to the Earth surface to about 8 km. Shallow depths occur mainly in the volcanic edifices. Deeper seismic events occurred outside the volcanic area. The duration magnitudes of the located microearthquakes range between 1 and 3. The Vp/Vs ratio and the low-Q values estimated suggest heterogeneous material properties in the volcanic structures mainly toward the El Azufre fault and the El Aguajito Caldera, where hydrothermal activity has been reported. The P- and T-axes of focal mechanisms for 90 microearthquakes suggest that the region is under N-S compression and E-W extension, in agreement with the regional tectonic stress field of the NW-SE right-lateral strike-slip transform fault system of the Gulf of California. [Spanish] En octubre de 1993 se llevo a cabo un monitoreo sismico en la region volcanica Las Tres Virgenes con el proposito de registrar la actividad sismica asociada a las estructuras volcanicas, al campo geotermico y a la tectonica local. Se localizaron 257 microsismos con hipocentros en los edificios volcanicos y a lo largo de la falla de rumbo, lateral derecha conocida como falla La Virgen. La profundidad focal de los sismos varia desde los muy cercanos a la superficie de la Tierra hasta los 8 km. Las profundidades someras ocurren principalmente en los edificios volcanicos. Los sismos mas profundos ocurren fuera del area volcanica. La magnitud de duracion de los microsismos localizados varia entre 1 y 3. La razon Vp/Vs y los valores bajos de Q que se estimaron en la zona sugieren un material con propiedades heterogeneas bajo las estructuras

  4. The role of the East Asian active margin in widespread extensional and strike-slip deformation in East Asia

    NARCIS (Netherlands)

    Schellart, Wouter P.; Lister, G. S.

    2005-01-01

    East Asia is a region of widespread deformation, dominated by normal and strike-slip faults. Deformation has been interpreted to result from extrusion tectonics related to the India-Eurasia collision, which started in the Early Eocene. In East and SE China, however, deformation started earlier than

  5. Fault Branching and Long-Term Earthquake Rupture Scenario for Strike-Slip Earthquake

    Science.gov (United States)

    Klinger, Y.; CHOI, J. H.; Vallage, A.

    2017-12-01

    Careful examination of surface rupture for large continental strike-slip earthquakes reveals that for the majority of earthquakes, at least one major branch is involved in the rupture pattern. Often, branching might be either related to the location of the epicenter or located toward the end of the rupture, and possibly related to the stopping of the rupture. In this work, we examine large continental earthquakes that show significant branches at different scales and for which ground surface rupture has been mapped in great details. In each case, rupture conditions are described, including dynamic parameters, past earthquakes history, and regional stress orientation, to see if the dynamic stress field would a priori favor branching. In one case we show that rupture propagation and branching are directly impacted by preexisting geological structures. These structures serve as pathways for the rupture attempting to propagate out of its shear plane. At larger scale, we show that in some cases, rupturing a branch might be systematic, hampering possibilities for the development of a larger seismic rupture. Long-term geomorphology hints at the existence of a strong asperity in the zone where the rupture branched off the main fault. There, no evidence of throughgoing rupture could be seen along the main fault, while the branch is well connected to the main fault. This set of observations suggests that for specific configurations, some rupture scenarios involving systematic branching are more likely than others.

  6. Influence of fault steps on rupture termination of strike-slip earthquake faults

    Science.gov (United States)

    Li, Zhengfang; Zhou, Bengang

    2018-03-01

    A statistical analysis was completed on the rupture data of 29 historical strike-slip earthquakes across the world. The purpose of this study is to examine the effects of fault steps on the rupture termination of these events. The results show good correlations between the type and length of steps with the seismic rupture and a poor correlation between the step number and seismic rupture. For different magnitude intervals, the smallest widths of the fault steps (Lt) that can terminate the rupture propagation are variable: Lt = 3 km for Ms 6.5 6.9, Lt = 4 km for Ms 7.0 7.5, Lt = 6 km for Ms 7.5 8.0, and Lt = 8 km for Ms 8.0 8.5. The dilational fault step is easier to rupture through than the compression fault step. The smallest widths of the fault step for the rupture arrest can be used as an indicator to judge the scale of the rupture termination of seismic faults. This is helpful for research on fault segmentation, as well as estimating the magnitude of potential earthquakes, and is thus of significance for the assessment of seismic risks.

  7. Preliminary results of very fast computation of Moment Magnitude and focal mechanism in the context of tsunami warning

    Science.gov (United States)

    Schindelé, François; Roch, Julien; Rivera, Luis

    2015-04-01

    Various methodologies were recently developed to compute the moment magnitude and the focal mechanism, thanks to the real time access to numerous broad-band seismic data. Several methods were implemented at the CENALT, in particular the W-Phase method developed by H. Kanamori and L. Rivera. For earthquakes of magnitudes in the range 6.5-9.0, this method provides accurate results in less than 40 minutes. The context of the tsunami warning in Mediterranean, a small basin impacted in less than one hour, and with small sources but some with high tsunami potential (Boumerdes 2003), a comprehensive tsunami warning system in that region should include very fast computation of the seismic parameters. The results of the values of Mw, the focal depth and the type of fault (reverse, normal, strike-slip) are the most relevant parameters expected for the tsunami warning. Preliminary results will be presented using data in the North-eastern and Mediterranean region for the recent period 2010-2014. This work is funded by project ASTARTE - - Assessment, Strategy And Risk Reduction for Tsunamis in Europe - FP7-ENV2013 6.4-3, Grant 603839

  8. Structural characteristics and implication on tectonic evolution of the Daerbute strike-slip fault in West Junggar area, NW China

    Science.gov (United States)

    Wu, Kongyou; Pei, Yangwen; Li, Tianran; Wang, Xulong; Liu, Yin; Liu, Bo; Ma, Chao; Hong, Mei

    2018-03-01

    The Daerbute fault zone, located in the northwestern margin of the Junggar basin, in the Central Asian Orogenic Belt, is a regional strike-slip fault with a length of 400 km. The NE-SW trending Daerbute fault zone presents a distinct linear trend in plain view, cutting through both the Zair Mountain and the Hala'alate Mountain. Because of the intense contraction and shearing, the rocks within the fault zone experienced high degree of cataclasis, schistosity, and mylonization, resulting in rocks that are easily eroded to form a valley with a width of 300-500 m and a depth of 50-100 m after weathering and erosion. The well-exposed outcrops along the Daerbute fault zone present sub-horizontal striations and sub-vertical fault steps, indicating sub-horizontal shearing along the observed fault planes. Flower structures and horizontal drag folds are also observed in both the well-exposed outcrops and high-resolution satellite images. The distribution of accommodating strike-slip splay faults, e.g., the 973-pluton fault and the Great Jurassic Trough fault, are in accordance with the Riedel model of simple shear. The seismic and time-frequency electromagnetic (TFEM) sections also demonstrate the typical strike-slip characteristics of the Daerbute fault zone. Based on detailed field observations of well-exposed outcrops and seismic sections, the Daerbute fault can be subdivided into two segments: the western segment presents multiple fault cores and damage zones, whereas the eastern segment only presents a single fault core, in which the rocks experienced a higher degree of rock cataclasis, schistosity, and mylonization. In the central overlapping portion between the two segments, the sediments within the fault zone are primarily reddish sandstones, conglomerates, and some mudstones, of which the palynological tests suggest middle Permian as the timing of deposition. The deformation timing of the Daerbute fault was estimated by integrating the depocenters' basinward

  9. The 2015 M7.2 Sarez, Central Pamir, Earthquake And The Importance Of Strike-Slip Faulting In The Pamir Interior: Insights From Geodesy And Field Observations

    Science.gov (United States)

    Metzger, Sabrina; Schurr, Bernd; Ratschbacher, Lothar; Schöne, Tilo; Kufner, Sofia-Katerina; Zhang, Yong; Sudhaus, Henriette

    2017-04-01

    The Pamir mountain range, located in the Northwest of the India-Asia collision zone, accommodates approximately one third of the northward advance of the Indian continent at this longitude (i. e. ˜34 mm/yr) mostly by shortening at its northern thrust system. Geodetic and seismic data sets reveal here a narrow zone of high deformation and M7+ earthquakes of mostly thrust type with some dextral strike-slip faulting observed, too. The Pamir interior shows sinistral strike-slip and normal faulting indicating north-south compression and east-west extension. In this tectonic setting the two largest instrumentally recorded earthquakes, the M7+ 1911 and 2015 earthquake events in the central Pamir occurred with left-lateral shear along a NE-SW rupture plane. We present the co-seismic deformation field of the 2015 earthquake observed by radar satellite interferometry (InSAR), SAR amplitude pixel offsets and high-rate Global Positioning System (GPS). The InSAR and pixel offset results suggest a 50+ km long rupture with sinistral fault offsets at the surface of more than 2 m on a yet unmapped fault trace of the Sarez Karakul Fault System (SKFS). A distributed slip model with a data-driven slip patch resolution yields a sub-vertical fault plane with a strike of N39.5 degrees and a rupture area of ˜80 x 40 km with a maximum slip of 2 m in the upper 10 km of the crust near the surface rupture. Field observations collected some nine months after the earthquake confirm the rupture mechanism, surface trace location and fault offset measurements as constrained by geodetic data. Diffuse deformation was observed across a 1-2 km wide zone, hosting primary fractures sub-parallel to the rupture strike with offsets of 2 m and secondary, en echelon fractures including Riedel shears and hybrid fractures often related to gravitational mass movements. The 1911 and 2015 earthquakes demonstrate the importance of sinistral strike-slip faulting on the SKFS, contributing both to shear between the

  10. Analysis of Focal Mechanism and Microseismicity around the Lusi Mud Eruption Site, East Java, Indonesia

    Science.gov (United States)

    Karyono, Karyono; Obermann, Anne; Mazzini, Adriano; Lupi, Matteo; Syafri, Ildrem; Abdurrokhim, Abdurrokhim; Masturyono, Masturyono; Hadi, Soffian

    2016-04-01

    The 29th of May 2006 numerous eruption sites started in northeast Java, Indonesia following to a M6.3 earthquake striking the island.Within a few weeks an area or nearly 2 km2 was covered by boiling mud and rock fragments and a prominent central crater (named Lusi) has been erupting for the last 9.5 years. The M.6.3 seismic event also triggered the activation of the Watukosek strike slip fault system that originates from the Arjuno-Welirang volcanic complex and extends to the northeast of Java hosting Lusi and other mud volcanoes. Since 2006 this fault system has been reactivated in numerous instances mostly following to regional seismic and volcanic activity. However the mechanism controlling this activity have never been investigated and remain poorly understood. In order to investigate the relationship existing between seismicity, volcanism, faulting and Lusi activity, we have deployed a network of 31 seismometers in the framework of the ERC-Lusi Lab project. This network covers a large region that monitors the Lusi activity, the Watukosek fault system and the neighboring Arjuno-Welirang volcanic complex. In particular, to understand the consistent pattern of the source mechanism, relative to the general tectonic stress in the study area, a detailed analysis has been carried out by performing the moment tensor inversion for the near field data collected from the network stations. Furthermore these data have been combined with the near field data from the regional network of the Meteorological, Climatological and Geophysical Agency of Indonesia that covers the whole country on a broader scale. Keywords: Lusi, microseismic event, focal mechanism

  11. The Damage and Geochemical Signature of a Crustal Scale Strike-Slip Fault Zone

    Science.gov (United States)

    Gomila, R.; Mitchell, T. M.; Arancibia, G.; Jensen Siles, E.; Rempe, M.; Cembrano, J. M.; Faulkner, D. R.

    2013-12-01

    Fluid-flow migration in the upper crust is strongly controlled by fracture network permeability and connectivity within fault zones, which can lead to fluid-rock chemical interaction represented as mineral precipitation in mesh veins and/or mineralogical changes (alteration) of the host rock. While the dimensions of fault damage zones defined by fracture intensity is beginning to be better understood, how such dimensions compare to the size of alteration zones is less well known. Here, we show quantitative structural and chemical analyses as a function of distance from a crustal-scale strike-slip fault in the Atacama Fault System, Northern Chile, to compare fault damage zone characteristics with its geochemical signature. The Jorgillo Fault (JF) is a ca. 18 km long NNW striking strike-slip fault cutting Mesozoic rocks with sinistral displacement of ca. 4 km. In the study area, the JF cuts through orthogranulitic and gabbroic rocks at the west (JFW) and the east side (JFE), respectively. A 200 m fault perpendicular transect was mapped and sampled for structural and XRF analyses of the core, damage zone and protolith. The core zone consists of a ca. 1 m wide cataclasite zone bounded by two fault gouge zones ca. 40 cm. The damage zone width defined by fracture density is ca. 50 m wide each side of the core. The damage zone in JFW is characterized by NW-striking subvertical 2 cm wide cataclastic rocks and NE-striking milimetric open fractures. In JFE, 1-20 mm wide chlorite, quartz-epidote and quartz-calcite veins, cut the gabbro. Microfracture analysis in JFW reveal mm-wide cataclasitic/ultracataclasitic bands with clasts of protolith and chlorite orientated subparallel to the JF in the matrix, calcite veins in a T-fractures orientation, and minor polidirectional chlorite veins. In JFE, chlorite filled conjugate fractures with syntaxial growth textures and evidence for dilational fracturing processes are seen. Closest to the core, calcite veins crosscut chlorite veins

  12. The Implications of Strike-Slip Earthquake Source Properties on the Transform Boundary Development Process

    Science.gov (United States)

    Neely, J. S.; Huang, Y.; Furlong, K.

    2017-12-01

    Subduction-Transform Edge Propagator (STEP) faults, produced by the tearing of a subducting plate, allow us to study the development of a transform plate boundary and improve our understanding of both long-term geologic processes and short-term seismic hazards. The 280 km long San Cristobal Trough (SCT), formed by the tearing of the Australia plate as it subducts under the Pacific plate near the Solomon and Vanuatu subduction zones, shows along-strike variations in earthquake behaviors. The segment of the SCT closest to the tear rarely hosts earthquakes > Mw 6, whereas the SCT sections more than 80 - 100 km from the tear experience Mw7 earthquakes with repeated rupture along the same segments. To understand the effect of cumulative displacement on SCT seismicity, we analyze b-values, centroid-time delays and corner frequencies of the SCT earthquakes. We use the spectral ratio method based on Empirical Green's Functions (eGfs) to isolate source effects from propagation and site effects. We find high b-values along the SCT closest to the tear with values decreasing with distance before finally increasing again towards the far end of the SCT. Centroid time-delays for the Mw 7 strike-slip earthquakes increase with distance from the tear, but corner frequency estimates for a recent sequence of Mw 7 earthquakes are approximately equal, indicating a growing complexity in earthquake behavior with distance from the tear due to a displacement-driven transform boundary development process (see figure). The increasing complexity possibly stems from the earthquakes along the eastern SCT rupturing through multiple asperities resulting in multiple moment pulses. If not for the bounding Vanuatu subduction zone at the far end of the SCT, the eastern SCT section, which has experienced the most displacement, might be capable of hosting larger earthquakes. When assessing the seismic hazard of other STEP faults, cumulative fault displacement should be considered a key input in

  13. Earthquake Activities Along the Strike-Slip Fault System on the Thailand-Myanmar Border

    Directory of Open Access Journals (Sweden)

    Santi Pailoplee

    2014-01-01

    Full Text Available This study investigates the present-day seismicity along the strike-slip fault system on the Thailand-Myanmar border. Using the earthquake catalogue the earthquake parameters representing seismic activities were evaluated in terms of the possible maximum magnitude, return period and earthquake occurrence probabilities. Three different hazardous areas could be distinguished from the obtained results. The most seismic-prone area was located along the northern segment of the fault system and can generate earthquakes of magnitude 5.0, 5.8, and 6.8 mb in the next 5, 10, and 50 years, respectively. The second most-prone area was the southern segment where earthquakes of magnitude 5.0, 6.0, and 7.0 mb might be generated every 18, 60, and 300 years, respectively. For the central segment, there was less than 30 and 10% probability that 6.0- and 7.0-mb earthquakes will be generated in the next 50 years. With regards to the significant infrastructures (dams in the vicinity, the operational Wachiralongkorn dam is situated in a low seismic hazard area with a return period of around 30 - 3000 years for a 5.0 - 7.0 mb earthquake. In contrast, the Hut Gyi, Srinakarin and Tha Thung Na dams are seismically at risk for earthquakes of mb 6.4 - 6.5 being generated in the next 50 years. Plans for a seismic-retrofit should therefore be completed and implemented while seismic monitoring in this region is indispensable.

  14. The San Andreas Fault and a Strike-slip Fault on Europa

    Science.gov (United States)

    1998-01-01

    The mosaic on the right of the south polar region of Jupiter's moon Europa shows the northern 290 kilometers (180 miles) of a strike-slip fault named Astypalaea Linea. The entire fault is about 810 kilometers (500 miles) long, the size of the California portion of the San Andreas fault on Earth which runs from the California-Mexico border north to the San Francisco Bay. The left mosaic shows the portion of the San Andreas fault near California's san Francisco Bay that has been scaled to the same size and resolution as the Europa image. Each covers an area approximately 170 by 193 kilometers(105 by 120 miles). The red line marks the once active central crack of the Europan fault (right) and the line of the San Andreas fault (left). A strike-slip fault is one in which two crustal blocks move horizontally past one another, similar to two opposing lanes of traffic. The overall motion along the Europan fault seems to have followed a continuous narrow crack along the entire length of the feature, with a path resembling stepson a staircase crossing zones which have been pulled apart. The images show that about 50 kilometers (30 miles) of displacement have taken place along the fault. Opposite sides of the fault can be reconstructed like a puzzle, matching the shape of the sides as well as older individual cracks and ridges that had been broken by its movements. Bends in the Europan fault have allowed the surface to be pulled apart. This pulling-apart along the fault's bends created openings through which warmer, softer ice from below Europa's brittle ice shell surface, or frozen water from a possible subsurface ocean, could reach the surface. This upwelling of material formed large areas of new ice within the boundaries of the original fault. A similar pulling apart phenomenon can be observed in the geological trough surrounding California's Salton Sea, and in Death Valley and the Dead Sea. In those cases, the pulled apart regions can include upwelled materials, but may

  15. Role of N-S strike-slip faulting in structuring of north-eastern Tunisia; geodynamic implications

    Science.gov (United States)

    Arfaoui, Aymen; Soumaya, Abdelkader; Ben Ayed, Noureddine; Delvaux, Damien; Ghanmi, Mohamed; Kadri, Ali; Zargouni, Fouad

    2017-05-01

    Three major compressional events characterized by folding, thrusting and strike-slip faulting occurred in the Eocene, Late Miocene and Quaternary along the NE Tunisian domain between Bou Kornine-Ressas-Msella and Cap Bon Peninsula. During the Plio-Quaternary, the Grombalia and Mornag grabens show a maximum of collapse in parallelism with the NNW-SSE SHmax direction and developed as 3rd order distensives zones within a global compressional regime. Using existing tectonic and geophysical data supplemented by new fault-kinematic observations, we show that Cenozoic deformation of the Mesozoic sedimentary sequences is dominated by first order N-S faults reactivation, this sinistral wrench system is responsible for the formation of strike-slip duplexes, thrusts, folds and grabens. Following our new structural interpretation, the major faults of N-S Axis, Bou Kornine-Ressas-Messella (MRB) and Hammamet-Korbous (HK) form an N-S first order compressive relay within a left lateral strike-slip duplex. The N-S master MRB fault is dominated by contractional imbricate fans, while the parallel HK fault is characterized by a trailing of extensional imbricate fans. The Eocene and Miocene compression phases in the study area caused sinistral strike-slip reactivation of pre-existing N-S faults, reverse reactivation of NE-SW trending faults and normal-oblique reactivation of NW-SE faults, creating a NE-SW to N-S trending system of east-verging folds and overlaps. Existing seismic tomography images suggest a key role for the lithospheric subvertical tear or STEP fault (Slab Transfer Edge Propagator) evidenced below this region on the development of the MRB and the HK relay zone. The presence of extensive syntectonic Pliocene on top of this crustal scale fault may be the result of a recent lithospheric vertical kinematic of this STEP fault, due to the rollback and lateral migration of the Calabrian slab eastward.

  16. Analogue modelling on the interaction between shallow magma intrusion and a strike-slip fault: Application on the Middle Triassic Monzoni Intrusive Complex (Dolomites, Italy)

    Science.gov (United States)

    Michail, Maria; Coltorti, Massimo; Gianolla, Piero; Riva, Alberto; Rosenau, Matthias; Bonadiman, Costanza; Galland, Olivier; Guldstrand, Frank; Thordén Haug, Øystein; Rudolf, Michael; Schmiedel, Tobias

    2017-04-01

    The southwestern part of the Dolomites in Northern Italy has undergone a short-lived Ladinian (Middle Triassic) tectono-magmatic event, forming a series of significant magmatic features. These intrusive bodies deformed and metamorphosed the Permo-Triassic carbonate sedimentary framework. In this study we focus on the tectono-magmatic evolution of the shallow shoshonitic Monzoni Intrusive Complex of this Ladinian event (ca 237 Ma), covering an area of 20 km^2. This NW-SE elongated intrusive structure (5 km length) shows an orogenic magmatic affinity which is in contrast to the tectonic regime at the time of intrusion. Strain analysis shows anorogenic transtensional displacement in accordance with the ENE-WSW extensional pattern in the central Dolomites during the Ladinian. Field interpretations led to a detailed description of the regional stratigraphic sequence and the structural features of the study area. However, the geodynamic context of this magmatism and the influence of the inherited strike-slip fault on the intrusion, are still in question. To better understand the specific natural prototype and the general mechanisms of magma emplacement in tectonically active areas, we performed analogue experiments defined by, but not limited to, first order field observations. We have conducted a systematic series of experiments in different tectonic regimes (static conditions, strike-slip, transtension). We varied the ratio of viscous to brittle stresses between magma and country rock, by injecting Newtonian fluids both of high and low viscosity (i.e. silicone oil/vegetable oil) into granular materials of varying cohesion (sand, silica flour, glass beads). The evolving surface and side view of the experiments were monitored by photogrammetric techniques for strain analyses and topographic evolution. In our case, the combination of the results from field and analogue experiments brings new insights regarding the tectonic regime, the geometry of the intrusive body, and

  17. The 2015 Mw7.2 Sarez Strike-Slip Earthquake in the Pamir Interior: Response to the Underthrusting of India's Western Promontory

    Science.gov (United States)

    Metzger, Sabrina; Schurr, Bernd; Ratschbacher, Lothar; Sudhaus, Henriette; Kufner, Sofia-Katerina; Schöne, Tilo; Zhang, Yong; Perry, Mason; Bendick, Rebecca

    2017-11-01

    The Pamir orogen, Central Asia, is the result of the ongoing northward advance of the Indian continent causing shortening inside Asia. Geodetic and seismic data place the most intense deformation along the northern rim of the Pamir, but the recent 7 December 2015, Mw7.2 Sarez earthquake occurred in the Pamir's interior. We present a distributed slip model of this earthquake using coseismic geodetic data and postseismic field observations. The earthquake ruptured an ˜80 km long, subvertical, sinistral fault consisting of three right-stepping segments from the surface to ˜30 km depth with a maximum slip of three meters in the upper 10 km of the crust. The coseismic slip model agrees well with en échelon secondary surface breaks that are partly influenced by liquefaction-induced mass movements. These structures reveal up to 2 m of sinistral offset along the northern, low-offset segment of modeled rupture. The 2015 event initiated close to the presumed epicenter of the 1911 Mw˜7.3 Lake Sarez earthquake, which had a similar strike-slip mechanism. These earthquakes highlight the importance of NE trending sinistral faults in the active tectonics of the Pamir. Strike-slip deformation accommodates shear between the rapidly northward moving eastern Pamir and the Tajik basin in the west and is part of the westward (lateral) extrusion of thickened Pamir plateau crust into the Tajik basin. The Sarez-Karakul fault system and the two large Sarez earthquakes likely are crustal expressions of the underthrusting of the northwestern leading edge of the Indian mantle lithosphere beneath the Pamir.

  18. Using an Earthquake Simulator to Model Tremor Along a Strike Slip Fault

    Science.gov (United States)

    Cochran, E. S.; Richards-Dinger, K. B.; Kroll, K.; Harrington, R. M.; Dieterich, J. H.

    2013-12-01

    We employ the earthquake simulator, RSQSim, to investigate the conditions under which tremor occurs in the transition zone of the San Andreas fault. RSQSim is a computationally efficient method that uses rate- and state- dependent friction to simulate a wide range of event sizes for long time histories of slip [Dieterich and Richards-Dinger, 2010; Richards-Dinger and Dieterich, 2012]. RSQSim has been previously used to investigate slow slip events in Cascadia [Colella et al., 2011; 2012]. Earthquakes, tremor, slow slip, and creep occurrence are primarily controlled by the rate and state constants a and b and slip speed. We will report the preliminary results of using RSQSim to vary fault frictional properties in order to better understand rupture dynamics in the transition zone using observed characteristics of tremor along the San Andreas fault. Recent studies of tremor along the San Andreas fault provide information on tremor characteristics including precise locations, peak amplitudes, duration of tremor episodes, and tremor migration. We use these observations to constrain numerical simulations that examine the slip conditions in the transition zone of the San Andreas Fault. Here, we use the earthquake simulator, RSQSim, to conduct multi-event simulations of tremor for a strike slip fault modeled on Cholame section of the San Andreas fault. Tremor was first observed on the San Andreas fault near Cholame, California near the southern edge of the 2004 Parkfield rupture [Nadeau and Dolenc, 2005]. Since then, tremor has been observed across a 150 km section of the San Andreas with depths between 16-28 km and peak amplitudes that vary by a factor of 7 [Shelly and Hardebeck, 2010]. Tremor episodes, comprised of multiple low frequency earthquakes (LFEs), tend to be relatively short, lasting tens of seconds to as long as 1-2 hours [Horstmann et al., in review, 2013]; tremor occurs regularly with some tremor observed almost daily [Shelly and Hardebeck, 2010; Horstmann

  19. Effects of Strike-Slip Fault Segmentation on Earthquake Energy and Seismic Hazard

    Science.gov (United States)

    Madden, E. H.; Cooke, M. L.; Savage, H. M.; McBeck, J.

    2014-12-01

    Many major strike-slip faults are segmented along strike, including those along plate boundaries in California and Turkey. Failure of distinct fault segments at depth may be the source of multiple pulses of seismic radiation observed for single earthquakes. However, how and when segmentation affects fault behavior and energy release is the basis of many outstanding questions related to the physics of faulting and seismic hazard. These include the probability for a single earthquake to rupture multiple fault segments and the effects of segmentation on earthquake magnitude, radiated seismic energy, and ground motions. Using numerical models, we quantify components of the earthquake energy budget, including the tectonic work acting externally on the system, the energy of internal rock strain, the energy required to overcome fault strength and initiate slip, the energy required to overcome frictional resistance during slip, and the radiated seismic energy. We compare the energy budgets of systems of two en echelon fault segments with various spacing that include both releasing and restraining steps. First, we allow the fault segments to fail simultaneously and capture the effects of segmentation geometry on the earthquake energy budget and on the efficiency with which applied displacement is accommodated. Assuming that higher efficiency correlates with higher probability for a single, larger earthquake, this approach has utility for assessing the seismic hazard of segmented faults. Second, we nucleate slip along a weak portion of one fault segment and let the quasi-static rupture propagate across the system. Allowing fractures to form near faults in these models shows that damage develops within releasing steps and promotes slip along the second fault, while damage develops outside of restraining steps and can prohibit slip along the second fault. Work is consumed in both the propagation of and frictional slip along these new fractures, impacting the energy available

  20. Holocene paleoearthquakes on the strike-slip Porters Pass Fault, Canterbury, New Zealand

    International Nuclear Information System (INIS)

    Howard, M.; Nicol, A.; Campbell, J.; Pettinga, J.R.

    2005-01-01

    The Porters Pass Fault comprises a series of discontinuous Holocene active traces which extend for c. 40 km between the Rakaia and Waimakariri Rivers in the foothills of the Southern Alps. There have been no historical earthquakes on the Porters Pass Fault (i.e., within the last 150 yr), and the purpose of this paper is to establish the timing and magnitudes of displacements on the fault at the ground surface during Holocene paleoearthquakes. Displaced geomorphic features (e.g., relict streams, stream channels, and ridge crests), measured using either tape measure (n = 20) or surveying equipment (n = 5), range from 5.5 to 33 m right lateral strike slip and are consistent with six earthquakes characterised by slip per event of c. 5-7 m. The timing of these earthquakes is constrained by radiocarbon dates from four trenches excavated across the fault and two auger sites from within swamps produced by ponding of drainage along the fault scarp. These data indicate markedly different Holocene earthquake histories along the fault length separated by a behavioural segment boundary near Lake Coleridge. On the eastern segment at least six Holocene earthquakes were identified at 8400-9000, 5700-6700, 4500-6000, 2300-2500, 800-1100, and 500-600 yr BP, producing an average recurrence interval of c. 1500 yr. On the western segment of the fault in the Rakaia River valley, a single surface-rupturing earthquake displaced Acheron Advance glacial deposits (c.10,000-14,000 yr in age) and may represent the southward continuation of the 2300-2500 yr event identified on the eastern segment. These data suggest Holocene slip rates of 3.2-4.1 mm/yr and 0.3-0.9 mm/yr on the eastern and western sections of the fault, respectively. Displacement and timing data suggest that earthquakes ruptured the western segment of the fault in no more than one-sixth of cases and that for a sample period of 10,000 yr the recurrence intervals were not characteristic. (auth). 45 refs., 10 figs., 3 tabs

  1. Transition from strike-slip faulting to oblique subduction: active tectonics at the Puysegur Margin, South New Zealand

    Science.gov (United States)

    Lamarche, Geoffroy; Lebrun, Jean-Frédéric

    2000-01-01

    South of New Zealand the Pacific-Australia (PAC-AUS) plate boundary runs along the intracontinental Alpine Fault, the Puysegur subduction front and the intraoceanic Puysegur Fault. The Puysegur Fault is located along Puysegur Ridge, which terminates at ca. 47°S against the continental Puysegur Bank in a complex zone of deformation called the Snares Zone. At Puysegur Trench, the Australian Plate subducts beneath Puysegur Bank and the Fiordland Massif. East of Fiordland and Puysegur Bank, the Moonlight Fault System (MFS) represents the Eocene strike-slip plate boundary. Interpretation of seafloor morphology and seismic reflection profiles acquired over Puysegur Bank and the Snares Zone allows study of the transition from intraoceanic strike-slip faulting along the Puysegur Ridge to oblique subduction at the Puysegur Trench and to better understand the genetic link between the Puysegur Fault and the MFS. Seafloor morphology is interpreted from a bathymetric dataset compiled from swath bathymetry data acquired during the 1993 Geodynz survey, and single beam echo soundings acquired by the NZ Royal Navy. The Snares Zone is the key transition zone from strike-slip faulting to subduction. It divides into three sectors, namely East, NW and SW sectors. A conspicuous 3600 m-deep trough (the Snares Trough) separates the NW and East sectors. The East sector is characterised by the NE termination of Puysegur Ridge into right-stepping en echelon ridges that accommodate a change of strike from the Puysegur Fault to the MFS. Between 48°S and 47°S, in the NW sector and the Snares Trough, a series of transpressional faults splay northwards from the Puysegur Fault. Between 49°50'S and 48°S, thrusts develop progressively at Puysegur Trench into a decollement. North of 48°S the Snares Trough develops between two splays of the Puysegur Fault, indicating superficial extension associated with the subsidence of Puysegur Ridge. Seismic reflection profiles and bathymetric maps show a

  2. Insights on the seismotectonics of the western part of northern Calabria (southern Italy) by integrated geological and geophysical data: Coexistence of shallow extensional and deep strike-slip kinematics

    Science.gov (United States)

    Ferranti, L.; Milano, G.; Pierro, M.

    2017-11-01

    We assess the seismotectonics of the western part of the border area between the Southern Apennines and Calabrian Arc, centered on the Mercure extensional basin, by integrating recent seismicity with a reconstruction of the structural frame from surface to deep crust. The analysis of low-magnitude (ML ≤ 3.5) events occurred in the area during 2013-2017, when evaluated in the context of the structural model, has revealed an unexpected complexity of seismotectonics processes. Hypocentral distribution and kinematics allow separating these events into three groups. Focal mechanisms of the shallower (kinematics. These results are consistent with the last kinematic event recorded on outcropping faults, and with the typical depth and kinematics of normal faulting earthquakes in the axial part of southern Italy. By contrast, intermediate ( 9-17 km) and deep ( 17-23 km) events have fault plane solutions characterized by strike- to reverse-oblique slip, but they differ from each other in the orientation of the principal axes. The intermediate events have P axes with a NE-SW trend, which is at odds with the NW-SE trend recorded by strike-slip earthquakes affecting the Apulia foreland plate in the eastern part of southern Italy. The intermediate events are interpreted to reflect reactivation of faults in the Apulia unit involved in thrust uplift, and appears aligned along an WNW-ESE trending deep crustal, possibly lithospheric boundary. Instead, deep events beneath the basin, which have P-axis with a NW-SE trend, hint to the activity of a deep overthrust of the Tyrrhenian back-arc basin crust over the continental crust of the Apulia margin, or alternatively, to a tear fault in the underthrust Apulia plate. Results of this work suggest that extensional faulting, as believed so far, does not solely characterizes the seismotectonics of the axial part of the Southern Apennines.

  3. Focal adhesions, stress fibers and mechanical tension

    Energy Technology Data Exchange (ETDEWEB)

    Burridge, Keith, E-mail: Keith_Burridge@med.unc.edu [Department of Cell Biology and Physiology, and Lineberger Comprehensive Cancer Center, 12-016 Lineberger, CB#7295, University of North Carolina, Chapel Hill, NC (United States); Guilluy, Christophe, E-mail: christophe.guilluy@univ-nantes.fr [Inserm UMR-S1087, CNRS UMR-C6291, L' institut du Thorax, and Université de Nantes, Nantes (France)

    2016-04-10

    Stress fibers and focal adhesions are complex protein arrays that produce, transmit and sense mechanical tension. Evidence accumulated over many years led to the conclusion that mechanical tension generated within stress fibers contributes to the assembly of both stress fibers themselves and their associated focal adhesions. However, several lines of evidence have recently been presented against this model. Here we discuss the evidence for and against the role of mechanical tension in driving the assembly of these structures. We also consider how their assembly is influenced by the rigidity of the substratum to which cells are adhering. Finally, we discuss the recently identified connections between stress fibers and the nucleus, and the roles that these may play, both in cell migration and regulating nuclear function. - Highlights: • The different types of stress fiber and focal adhesion are described. • We discuss the controversy about tension and assembly of these structures. • We describe the different models used to investigate assembly of these structures. • The influence of substratum rigidity is discussed. • Stress fiber connections to the nucleus are reviewed.

  4. Strike-slip linked core complexes: A new kinematic model of basement rock exhumation in a crustal-scale fault system

    Science.gov (United States)

    Meyer, Sven Erik; Passchier, Cees; Abu-Alam, Tamer; Stüwe, Kurt

    2014-05-01

    Metamorphic core complexes usually develop as extensional features during continental crustal thinning, such as the Basin and Range and the Aegean Terrane. The Najd fault system in Saudi Arabia is a 2000 km-long and 400 km-wide complex network of crustal-scale strike-slip shear zones in a Neoproterozoic collision zone. Locally, the anastomosing shear zones lead to exhumation of lower crustal segments and represent a new kinematic model for the development of core complexes. We report on two such structures: the Qazaz complex in Saudi Arabia and the Hafafit complex in Egypt. The 15 km-wide Qazaz complex is a triangular dome of gently dipping mylonitic foliations within the 140 km-long sinistral strike-slip Qazaz mylonite zone. The gneissic dome consists of high-grade rocks, surrounded by low-grade metasediments and metavolcanics. The main SE-trending strike-slip Qazaz shear zone splits southwards into two branches around the gneiss dome: the western branch is continuous with the shallow dipping mylonites of the dome core, without overprinting, and changes by more than 90 degrees from a NS-trending strike-slip zone to an EW-trending 40 degree south-dipping detachment that bounds the gneiss dome to the south. The eastern SE-trending sinistral strike-slip shear zone branch is slightly younger and transects the central dome fabrics. The gneiss dome appears to have formed along a jog in the strike-slip shear zone during 40 km of horizontal strike-slip motion, which caused local exhumation of lower crustal rocks by 25 km along the detachment. The eastern shear zone branch formed later during exhumation, transacted the gneiss dome and offset the two parts by another 70 km. The Hafafit core complex in Egypt is of similar shape and size to the Qazaz structure, but forms the northern termination of a sinistral strike-slip zone that is at least 100 km in length. This zone may continue into Saudi Arabia as the Ajjaj shear zone for another 100 km. The NW trending strike slip

  5. Analysis of Seismotektonic Patterns in Sumatra Region Based on the Focal Mechanism of Earthquake Period 1976-2016

    Science.gov (United States)

    Indah, F. P.; Syafriani, S.; Andiyansyah, Z. S.

    2018-04-01

    Sumatra is in an active subduction zone between the indo-australian plate and the eurasian plate and is located at a fault along the sumatra fault so that sumatra is vulnerable to earthquakes. One of the ways to find out the cause of earthquake can be done by identifying the type of earthquake-causing faults based on earthquake of focal mechanism. The data used to identify the type of fault cause of earthquake is the earth tensor moment data which is sourced from global cmt period 1976-2016. The data used in this research using magnitude m ≥ 6 sr. This research uses gmt software (generic mapping tolls) to describe the form of fault. From the research result, it is found that the characteristics of fault field that formed in every region in sumatera island based on data processing and data of earthquake history of 1976-2016 period that the type of fault in sumatera fault is strike slip, fault type in mentawai fault is reverse fault (rising faults) and dip-slip, while the fault type in the subduction zone is dip-slip.

  6. Structural setting and kinematics of Nubian fault system, SE Western Desert, Egypt: An example of multi-reactivated intraplate strike-slip faults

    Science.gov (United States)

    Sakran, Shawky; Said, Said Mohamed

    2018-02-01

    Detailed surface geological mapping and subsurface seismic interpretation have been integrated to unravel the structural style and kinematic history of the Nubian Fault System (NFS). The NFS consists of several E-W Principal Deformation Zones (PDZs) (e.g. Kalabsha fault). Each PDZ is defined by spectacular E-W, WNW and ENE dextral strike-slip faults, NNE sinistral strike-slip faults, NE to ENE folds, and NNW normal faults. Each fault zone has typical self-similar strike-slip architecture comprising multi-scale fault segments. Several multi-scale uplifts and basins were developed at the step-over zones between parallel strike-slip fault segments as a result of local extension or contraction. The NNE faults consist of right-stepping sinistral strike-slip fault segments (e.g. Sin El Kiddab fault). The NNE sinistral faults extend for long distances ranging from 30 to 100 kms and cut one or two E-W PDZs. Two nearly perpendicular strike-slip tectonic regimes are recognized in the NFS; an inactive E-W Late Cretaceous - Early Cenozoic dextral transpression and an active NNE sinistral shear.

  7. Late Pleistocene-Holocene Activity of the Strike-slip Xianshuihe Fault Zone, Tibetan Plateau, Inferred from Tectonic Landforms

    Science.gov (United States)

    Lin, A.; Yan, B.

    2017-12-01

    Knowledges on the activity of the strike-slip fault zones on the Tibetan Plateau have been promoted greatly by the interpretation of remote sensing images (Molnar and Tapponnier, 1975; Tapponnier and Molnar, 1977). The active strike-slip Xianshuihe-Xiaojiang Fault System (XXFS), with the geometry of an arc projecting northeastwards, plays an important role in the crustal deformation of the Tibetan Plateau caused by the continental collision between the Indian and Eurasian plates. The Xianshuihe Fault Zone (XFZ) is located in the central segment of the XXFS and extends for 370 km, with a maximum sinistral offset of 60 km since 13‒5 Ma. In this study, we investigated the tectonic landforms and slip rate along the central segment of the left-lateral strike-slip XFZ. Field investigations and analysis of ttectonic landforms show that horizontal offset has been accumulated on the topographical markers of different scales that developed since the Last Glacial Maximum (LGM). The central segment of the XFZ is composed of three major faults: Yalahe, Selaha, and Zheduotang faults showing a right-stepping echelon pattern, that is characterized by systematical offset of drainages, alluvial fans and terrace risers with typical scissoring structures, indicating a structural feature of left-lateral strike-slip fault. Based on the offset glacial morphology and radiocarbon dating ages, we estimate the Late Pleistocene-Holocene slip rate to be 10 mm/yr for the central segment of the XFZ, which is consistent with that estimated from the GPS observations and geological evidence as reported previously. Across the central segment of the XFZ, the major Selaha and Zheduotang faults participate a slip rate of 5.8 mm/yr and 3.4 mm/yr, respectively. Detailed investigations of tectonic landforms are essential for the understanding the activity of active faults. Our findings suggest that the left-lateral slipping of the XFZ partitions the deformation of eastward extrusion and northeastward

  8. DESI focal plate mechanical integration and cooling

    Science.gov (United States)

    Lambert, A. R.; Besuner, R. W.; Claybaugh, T. M.; Silber, J. H.

    2016-08-01

    The Dark Energy Spectroscopic Instrument (DESI) is under construction to measure the expansion history of the Universe using the Baryon Acoustic Oscillation technique[1]. The spectra of 40 million galaxies over 14000 sq. deg will be measured during the life of the experiment. A new prime focus corrector for the KPNO Mayall telescope will deliver light to 5000 fiber optic positioners. The fibers in turn feed ten broad-band spectrographs. This paper describes the mechanical integration of the DESI focal plate and the thermal system design. The DESI focal plate is comprised of ten identical petal assemblies. Each petal contains 500 robotic fiber positioners. Each petal is a complete, self-contained unit, independent from the others, with integrated power supply, controllers, fiber routing, and cooling services. The major advantages of this scheme are: (1) supports installation and removal of complete petal assemblies in-situ, without disturbing the others, (2) component production, assembly stations, and test procedures are repeated and parallelizable, (3) a complete, full-scale prototype can be built and tested at an early date, (4) each production petal can be surveyed and tested as a complete unit, prior to integration, from the fiber tip at the focal surface to the fiber slit at the spectrograph. The ten petal assemblies will be installed in a single integration ring, which is mounted to the DESI corrector. The aluminum integration ring attaches to the steel corrector barrel via a flexured steel adapter, isolating the focal plate from differential thermal expansions. The plate scale will be kept stable by conductive cooling of the petal assembly. The guider and wavefront sensors (one per petal) will be convectively cooled by forced flow of air. Heat will be removed from the system at ten liquid-cooled cold plates, one per petal, operating at ambient temperature. The entire focal plate structure is enclosed in an insulating shroud, which serves as a thermal barrier

  9. Three-dimensional shuffling of horses in a strike-slip duplex: an example from the Lambertville sill, New Jersey

    Science.gov (United States)

    Laney, Stephen E.; Gates, Alexander E.

    1996-06-01

    Detailed analysis of a dextral strike-slip duplex within the relatively isotropic rocks of the Lambertville sill, New Jersey indicates that horses have experienced vertical, horizontal and oblique movements resulting from extrusional shuffling within a restraining bend. This is the first documentation of the three-dimensional movement of horses within a strike-slip duplex. Deformation within the duplex shows a complex system of early synthetic fractures and reverse faults followed by antithetic fractures which dissect previously continuous slab-shaped horses into diamond-shaped lenses. Most faults are oblique slip. Antithetic fault movements and clockwise rigid rotation of horses dominate the south half of the duplex and synthetic movements and counterclockwise rotations dominate the north half. Slickenline plunges on curved horse-bounding fault surfaces within the duplex range from nearly horizontal to 40° resulting in both lateral movements (middle) to normal movements (tails) on a single horse. Curved slickensides commonly have opposite senses of movement on either side of individual horses indicating relative emergence or submergence. Such a geometry could also result from a group of horses moving in the same oblique direction but at different rates. These complex extrusional-type movements were observed in both cross-sectional and plan views. The net result of the movements is a contraction or flattening of the duplex normal to the bounding faults. The horses shifted to accommodate this flattening as overall displacement was transferred between the bounding faults along curved internal faults.

  10. Multispectral linear array (MLA) focal plane mechanical and thermal design

    Science.gov (United States)

    Mitchell, A. S.; Kaminski, E. F.

    1982-01-01

    The mechanical and thermal design of an integrated focal plane subsystem of a Multispectral Linear Array (MLA) instrument is discussed in terms of focal-plane alignment, thermoelastic performance, and thermal requirements. The modular construction and thermal control of the focal plane array are discussed.

  11. Right-lateral shear and rotation as the explanation for strike-slip faulting in eastern Tibet

    Science.gov (United States)

    England, Philip; Molnar, Peter

    1990-01-01

    Bounds are placed here on the rate of rotation proposed by Cobbold and Davy (1988) for the major strike-slip faults in the eastern Tibetan Plateau. It is also concluded here that the image of lateral transport on such faults, known also as continental escape, extrusion, or expulsion, is an illusion, and that instead the left-lateral slip on east-striking plates in eastern Tibet is a manifestation of north-striking right-lateral simple shear. If this conclusion is correct, the east-striking left-lateral faults and the crustal blocks between them are rotating clockwise at 1-2 deg/Myr, the east-west dimension of eastern Tibet is shortening at 10-20 mm/yr, and little material is moving eastward out of India's path into Eursasia by left-lateral simple shear.

  12. A nonlinear least-squares inverse analysis of strike-slip faulting with application to the San Andreas fault

    Science.gov (United States)

    Williams, Charles A.; Richardson, Randall M.

    1988-01-01

    A nonlinear weighted least-squares analysis was performed for a synthetic elastic layer over a viscoelastic half-space model of strike-slip faulting. Also, an inversion of strain rate data was attempted for the locked portions of the San Andreas fault in California. Based on an eigenvector analysis of synthetic data, it is found that the only parameter which can be resolved is the average shear modulus of the elastic layer and viscoelastic half-space. The other parameters were obtained by performing a suite of inversions for the fault. The inversions on data from the northern San Andreas resulted in predicted parameter ranges similar to those produced by inversions on data from the whole fault.

  13. Stress near geometrically complex strike-slip faults - Application to the San Andreas fault at Cajon Pass, southern California

    Science.gov (United States)

    Saucier, Francois; Humphreys, Eugene; Weldon, Ray, II

    1992-01-01

    A model is presented to rationalize the state of stress near a geometrically complex major strike-slip fault. Slip on such a fault creates residual stresses that, with the occurrence of several slip events, can dominate the stress field near the fault. The model is applied to the San Andreas fault near Cajon Pass. The results are consistent with the geological features, seismicity, the existence of left-lateral stress on the Cleghorn fault, and the in situ stress orientation in the scientific well, found to be sinistral when resolved on a plane parallel to the San Andreas fault. It is suggested that the creation of residual stresses caused by slip on a wiggle San Andreas fault is the dominating process there.

  14. Analogue Modeling of Oblique Convergent Strike-Slip Faulting and Application to The Seram Island, Eastern Indonesia

    Directory of Open Access Journals (Sweden)

    Benyamin Sapiie

    2014-12-01

    Full Text Available DOI:10.17014/ijog.v1i3.189Sandbox experiment is one of the types of analogue modeling in geological sciences in which the main purpose is simulating deformation style and structural evolution of the sedimentary basin.  Sandbox modeling is one of the effective ways in conducting physically modeling and evaluates complex deformation of sedimentary rocks. The main purpose of this paper is to evaluate structural geometry and deformation history of oblique convergent deformation using of integrated technique of analogue sandbox modeling applying to deformation of Seram Fold-Thrust-Belt (SFTB in the Seram Island, Eastern Indonesia. Oblique convergent strike-slip deformation has notoriously generated area with structural complex geometry and pattern resulted from role of various local parameters that control stress distributions. Therefore, a special technique is needed for understanding and solving such problem in particular to relate 3D fault geometry and its evolution. The result of four case (Case 1 to 4 modeling setting indicated that two of modeling variables clearly affected in our sandbox modeling results; these are lithological variation (mainly stratigraphy of Seram Island and pre-existing basement fault geometry (basement configuration. Lithological variation was mainly affected in the total number of faults development.  On the other hand, pre-existing basement fault geometry was highly influenced in the end results particularly fault style and pattern as demonstrated in Case 4 modeling.  In addition, this study concluded that deformation in the Seram Island is clearly best described using oblique convergent strike-slip (transpression stress system.

  15. Geologic Inheritance and Earthquake Rupture Processes: The 1905 M ≥ 8 Tsetserleg-Bulnay Strike-Slip Earthquake Sequence, Mongolia

    Science.gov (United States)

    Choi, Jin-Hyuck; Klinger, Yann; Ferry, Matthieu; Ritz, Jean-François; Kurtz, Robin; Rizza, Magali; Bollinger, Laurent; Davaasambuu, Battogtokh; Tsend-Ayush, Nyambayar; Demberel, Sodnomsambuu

    2018-02-01

    In 1905, 14 days apart, two M 8 continental strike-slip earthquakes, the Tsetserleg and Bulnay earthquakes, occurred on the Bulnay fault system, in Mongolia. Together, they ruptured four individual faults, with a total length of 676 km. Using submetric optical satellite images "Pleiades" with ground resolution of 0.5 m, complemented by field observation, we mapped in detail the entire surface rupture associated with this earthquake sequence. Surface rupture along the main Bulnay fault is 388 km in length, striking nearly E-W. The rupture is formed by a series of fault segments that are 29 km long on average, separated by geometric discontinuities. Although there is a difference of about 2 m in the average slip between the western and eastern parts of the Bulnay rupture, along-fault slip variations are overall limited, resulting in a smooth slip distribution, except for local slip deficit at segment boundaries. We show that damage, including short branches and secondary faulting, associated with the rupture propagation, occurred significantly more often along the western part of the Bulnay rupture, while the eastern part of the rupture appears more localized and thus possibly structurally simpler. Eventually, the difference of slip between the western and eastern parts of the rupture is attributed to this difference of rupture localization, associated at first order with a lateral change in the local geology. Damage associated to rupture branching appears to be located asymmetrically along the extensional side of the strike-slip rupture and shows a strong dependence on structural geologic inheritance.

  16. Effect of inherited structures on strike-slip plate boundaries: insight from analogue modelling of the central Levant Fracture System, Lebanon

    Science.gov (United States)

    Ghalayini, Ramadan; Daniel, Jean-Marc; Homberg, Catherine; Nader, Fadi

    2015-04-01

    Analogue sandbox modeling is a tool to simulate deformation style and structural evolution of sedimentary basins. The initial goal is to test what is the effect of inherited and crustal structures on the propagation, evolution, and final geometry of major strike-slip faults at the boundary between two tectonic plates. For this purpose, we have undertaken a series of analogue models to validate and reproduce the structures of the Levant Fracture System, a major NNE-SSW sinistral strike-slip fault forming the boundary between the Arabian and African plates. Onshore observations and recent high quality 3D seismic data in the Levant Basin offshore Lebanon demonstrated that Mesozoic ENE striking normal faults were reactivated into dextral strike-slip faults during the Late Miocene till present day activity of the plate boundary which shows a major restraining bend in Lebanon with a ~ 30°clockwise rotation in its trend. Experimental parameters consisted of a silicone layer at the base simulating the ductile crust, overlain by intercalated quartz sand and glass sand layers. Pre-existing structures were simulated by creating a graben in the silicone below the sand at an oblique (>60°) angle to the main throughgoing strike-slip fault. The latter contains a small stepover at depth to create transpression during sinistral strike-slip movement and consequently result in mountain building similarly to modern day Lebanon. Strike-slip movement and compression were regulated by steady-speed computer-controlled engines and the model was scanned using a CT-scanner continuously while deforming to have a final 4D model of the system. Results showed that existing normal faults were reactivated into dextral strike-slip faults as the sinistral movement between the two plates accumulated. Notably, the resulting restraining bend is asymmetric and segmented into two different compartments with differing geometries. One compartment shows a box fold anticline, while the second shows an

  17. Analogue modelling of a reactivated, basement controlled strike-slip zone, Sierra de Albarracín, Spain: application of sandbox modelling to polyphase deformation

    NARCIS (Netherlands)

    Merten, S.; Smit, W.G.; Nieuwland, D.A.; Rondeel, H.E.

    2006-01-01

    This paper presents the results of an analogue modelling study on the reactivation of Riedel shears generated by basement-induced sinistral strike-slip faulting. It is based on a natural example in the Sierra de Albarracín, Iberian Range (Spain). The area has a polyphase deformation history, defined

  18. NW transverse fault system in Southern Bogota, Colombia: New seismologic and structural evidences derived from focal mechanisms and stress field determination

    Science.gov (United States)

    Angel Amaya, J.; Fierro Morales, J.; Ordoñez Potes, M.; Blanco, M.

    2012-12-01

    We present new seismological, morphotectonic and structural data of the Southern Bogota area. The goals of the study were to characterize the NW transverse fault system and to evaluate its effect on seismic wave's generation and propagation. The data set included epicenters of the RSNC (Red Sismologica Nacional de Colombia) catalog over the period 1993-2012, historical description of seismic events (period 1644-1921), structural field data (scale 1:100000) and remote sensors interpretation. The methodology included the structural analysis of over 476 faults having a known sense of offset by using a least squares iterative inversion outlined by Angelier (1984) to determinate the mean deviatoric principal stress tensor. Preliminary conclusions showed that both propagation medium and direction are determined by the structural and mechanic conditions of the Southern Bogota Shear Zone (SBSZ) defined by Fierro & Angel, (2008) as a NW-SE oblique-slip fault zone within sinistral and normal regimes. Based on both data sources (focal mechanism and field structural data) we attempted to reconstruct the stress field starting with a strike slip faulting stress regime (S2 vertical), the solution yielded a ENE-WSW orientation for horizontal principal stress (S1). It is hypothesized that the NW oblique-slip fault zone may generate and/or propagate seismic waves, as a local source, implying local hazard to Bogota the capital city of Colombia with over 8 million habitants.

  19. A Physical Analog Model of Strike-Slip Faulting for Model-Based Inquiry in the Classroom

    Science.gov (United States)

    Curren, I. S.; Glesener, G.

    2013-12-01

    Geoscience educators often use qualitative physical analog models to demonstrate natural processes; while these are effective teaching tools, they often neglect the fundamental scientific practices that make up the core of scientific work. Physical analog models with dynamic properties that can be manipulated and measured quantitatively in real-time, on the other hand, can give students the opportunity to explore, observe and empirically test their own ideas and hypotheses about the relevant target concepts within a classroom setting. Providing classroom content for inquiry, such as a hands-on physical analog model, which fosters students' production and refinement of their mental models in participatory and discursive activities have been argued by many education researchers to help students build a deeper understanding of science and scientific reasoning. We present a physical analog model that was originally developed by UCLA's Modeling and Educational Demonstrations Laboratory (MEDL) for the purpose of engaging students in the study of elastic rebound on a strike-slip fault; it was later modified to accommodate research of complex tectonic processes associated with strike-slip faulting, which are currently debated by scientists in both the geology and geophysics disciplines. During experimentation, it became clear that this new design could be used as a relevant resource for inquiry from which students would be able to make and discuss real-time empirical measurements and observations to help them infer causal accounts of theoretical and/or unobservable dynamic processes within the Earth's crust. In our poster session, we will: 1) demonstrate the physical analog model; 2) describe various real-time data collection tools, as well as quantitative methods students can use to process their data; and 3) describe the surficial, structural and relational similarities between the physical analog model and the target concepts intended for students to explore in the

  20. The geometry of pull-apart basins in the southern part of Sumatran strike-slip fault zone

    Science.gov (United States)

    Aribowo, Sonny

    2018-02-01

    Models of pull-apart basin geometry have been described by many previous studies in a variety tectonic setting. 2D geometry of Ranau Lake represents a pull-apart basin in the Sumatran Fault Zone. However, there are unclear geomorphic traces of two sub-parallel overlapping strike-slip faults in the boundary of the lake. Nonetheless, clear geomorphic traces that parallel to Kumering Segment of the Sumatran Fault are considered as inactive faults in the southern side of the lake. I demonstrate the angular characteristics of the Ranau Lake and Suoh complex pull-apart basins and compare with pull-apart basin examples from published studies. I use digital elevation model (DEM) image to sketch the shape of the depression of Ranau Lake and Suoh Valley and measure 2D geometry of pull-apart basins. This study shows that Ranau Lake is not a pull-apart basin, and the pull-apart basin is actually located in the eastern side of the lake. Since there is a clear connection between pull-apart basin and volcanic activity in Sumatra, I also predict that the unclear trace of the pull-apart basin near Ranau Lake may be covered by Ranau Caldera and Seminung volcanic products.

  1. Structure of the Melajo clay near Arima, Trinidad and strike-slip motion in the El Pilar fault zone

    Science.gov (United States)

    Robertson, P.; Burke, K.; Wadge, G.

    1985-01-01

    No consensus has yet emerged on the sense, timing and amount of motion in the El Pilar fault zone. As a contribution to the study of this problem, a critical area within the zone in North Central Trinidad has been mapped. On the basis of the mapping, it is concluded that the El Pilar zone has been active in right-lateral strike-slip motion during the Pleistocene. Recognition of structural styles akin to those of the mapped area leads to the suggestion that the El Pilar zone is part of a 300 km wide plate boundary zone extending from the Orinoco delta northward to Grenada. Lateral motion of the Caribbean plate with respect to South America has been suggested to amount to 1900 km in the last 38 Ma. Part of this displacement since the Miocene can be readily accommodated within the broad zone identified here. No one fault system need account for more than a fraction of the total motion and all faults need not be active simultaneously.

  2. Domino structures evolution in strike-slip shear zones; the importance of the cataclastic flow

    Science.gov (United States)

    Moreira, N.; Dias, R.

    2018-05-01

    The Porto-Tomar-Ferreira do Alentejo dextral Shear Zone is one of the most important structures of the Iberian Variscides. In its vicinity, close to Abrantes (Central Portugal), a localized heterogeneous strain pattern developed in a decimetric metamorphic siliceous multilayer. This complex pattern was induced by the D2 dextral shearing of the early S0//S1 foliation in brittle-ductile conditions, giving rise to three main shear zone families. One of these families, with antithetic kinematics, delimits blocks with rigid clockwise rotation surrounded by coeval cataclasites, generating a local domino structure. The proposed geometrical and kinematic analysis, coupled with statistical studies, highlights the relation between subsidiary shear zones and the main shear zone. Despite the heterogeneous strain pattern, a quantitative approach of finite strain was applied based on the restoration of the initial fracture pattern. This approach shows the importance of the cataclastic flow coupled with the translational displacement of the domino domain in solving space problems related to the rigid block rotation. Such processes are key in allowing the rigid block rotation inside shear zones whenever the simple shear component is a fundamental mechanism.

  3. Active stress from earthquake focal mechanisms along the Padan-Adriatic side of the Northern Apennines (Italy), with considerations on stress magnitudes and pore-fluid pressures

    Science.gov (United States)

    Boncio, Paolo; Bracone, Vito

    2009-10-01

    The active tectonic regime along the outer Northern Apennines (Padan-Adriatic area) is a matter of debate. We analyse the active tectonic regime by systematically inverting earthquake focal mechanisms in terms of their driving stress field, comparing two different stress inversion methods. Earthquakes within the area often deviate from Andersonian conditions, being characterized by reverse or transpressional slip on high-angle faults even if the regime is almost purely thrust faulting (e.g. Reggio Emilia 1996 and Faenza 2000 earthquakes). We analyse the stress conditions at faulting for the Reggio Emilia and Faenza earthquakes in order to infer the stress magnitudes and the possible role of fluid pressures. The stress analysis defines a consistent pattern of sub-horizontal active deviatoric compression arranged nearly perpendicular to the eastern front of the Padan-Adriatic fold-and-thrust system, independent of the stress inversion method used. The results are consistent with active compression operating within the Padan-Adriatic belt. The stress field is thrust faulting (sub-vertical σ3), except for the Cesena-Forlì and Ancona areas, where a strike-slip regime (sub-vertical or steeply-plunging σ2) operates. The strike-slip regimes are interpreted as being caused by the superposition of local tensional stresses due to oroclinal bending (i.e. rotations of the belt about vertical axes) on the regional compressional stress field. Kinematic complexities characterize the 1996 Reggio Emilia seismic sequence. The distribution of these complexities is not random, suggesting that they are due to local variations of the regional stress field within the unfaulted rocks surrounding the coseismic rupture. The stress conditions at faulting for the Reggio Emilia 1996 and Faenza 2000 earthquakes, coupled with the observation that seismicity in the Padan-Adriatic area often occurs in swarms, suggest that high pore-fluid pressures (Pf ≥ 70% of the lithostatic load) operate

  4. The feature of the focal mechanism solutions and tectonic stress field around the focus of Zaduo earthquake (Ms 6.3) in eastern Tibet

    Science.gov (United States)

    Yang, Y.; Zeng, Z.; Shuang, X.; Li, X.

    2017-12-01

    On 17th October, 2016, an earthquake of Ms6.3 occurred in Zaduo County, Qinghai Province (32.9°N, 95.0°E), 159 km away from the epicenter of Yushu Ms7.3 earthquake in 2011. The earthquake is located in the eastern Tibet Plateau and the north region of Eastern Himalayan Syntaxis. Using the broadband seismic waveform data form regional networks, we determined the focal mechanism solutions (FMSs) of 83 earthquakes (M>3.5) occurred in Zaduo and its adjacent areas from 2009 to 2017. We also collected another 63 published FMSs and then inversed the current tectonic stress field in study region using the damped linear inversion method. The results show that the Zaduo earthquake is a normal oblique earthquake. The FMSs in our study region are mainly in strike-slip and normal fault patterns. The strike-slip earthquakes are mainly distributed in Yushu-Ganzi, Zaduo and Yanshiping fault zones, and the normal faulting events occurred in Nu Jiang fault zone and Nierong County and its vicinity, the south and southwest of the study areas. The tectonic stress field results indicate that the stress distribution in the north and east of the study region changes homogeneously and slowly. From west to east, the σ1 gradually changes from NNE to NE direction, and the σ3 varies from NWW to NW direction. Both the maximum (σ1) and minimum (σ3) principal stress axes in the study area are nearly horizontal, except in the Nu Jiang fault zone and its vicinity, the south of the study area, which is in a normal faulting stress regime (σ1 is vertical and σ3 is horizontal). The localized normal faulting stress field in the south area, which is almost limited in a semicircle, indicates that a high pressure and low viscosity body with low S-wave velocity and high conductivity might exists beneath the anomaly area. And there may be another semicircle abnormal area beyond the south of the study region. Waveform data for this study are provided by Data Management Centre of China National Seismic

  5. Dynamic response to strike-slip tectonic control on the deposition and evolution of the Baranof Fan, Gulf of Alaska

    Science.gov (United States)

    Walton, Maureen A. L.; Gulick, Sean P. S.; Reece, Robert S.; Barth, Ginger A.; Christeson, Gail L.; VanAvendonk, Harm J.

    2014-01-01

    The Baranof Fan is one of three large deep-sea fans in the Gulf of Alaska, and is a key component in understanding large-scale erosion and sedimentation patterns for southeast Alaska and western Canada. We integrate new and existing seismic reflection profiles to provide new constraints on the Baranof Fan area, geometry, volume, and channel development. We estimate the fan’s area and total sediment volume to be ∼323,000 km2 and ∼301,000 km3, respectively, making it among the largest deep-sea fans in the world. We show that the Baranof Fan consists of channel-levee deposits from at least three distinct aggradational channel systems: the currently active Horizon and Mukluk channels, and the waning system we call the Baranof channel. The oldest sedimentary deposits are in the northern fan, and the youngest deposits at the fan’s southern extent; in addition, the channels seem to avulse southward consistently through time. We suggest that Baranof Fan sediment is sourced from the Coast Mountains in southeastern Alaska, transported offshore most recently via fjord to glacial sea valley conduits. Because of the translation of the Pacific plate northwest past sediment sources on the North American plate along the Queen Charlotte strike-slip fault, we suggest that new channel formation, channel beheadings, and southward-migrating channel avulsions have been influenced by regional tectonics. Using a simplified tectonic reconstruction assuming a constant Pacific plate motion of 4.4 cm/yr, we estimate that Baranof Fan deposition initiated ca. 7 Ma.

  6. (Plio-)Pleistocene alluvial-lacustrine basin infill evolution in a strike-slip active zone (Northern Andes, Western-Central Cordilleras, Colombia)

    OpenAIRE

    SUTER, F.; NEUWERTH, R.; GORIN, G.; GUZMÁN, C.

    2009-01-01

    The (Plio)-Pleistocene Zarzal Formation was deposited in the Cauca Depression and Quindío-Risaralda Basin between the Western and Central Cordilleras (Northern Andes). This area is structurally located on the transcurrent Romeral Fault System (RFS). Because of the interaction between the Nazca plate and the Chocó-Panamá block (an active indenter), the RFS strike-slip component changes direction around the study zone (dextral in the south, senestral in the north). Zarzal sediments are the olde...

  7. THE ILICA BRANCH OF THE SOUTHEASTERN ESKIŞEHIR FAULT ZONE: AN ACTIVE RIGHT LATERAL STRIKE-SLIP STRUCTURE IN CENTRAL ANATOLIA, TURKEY

    Directory of Open Access Journals (Sweden)

    Korhan ESAT

    2016-12-01

    Full Text Available The Eskişehir Fault Zone is one of the prominent neotectonic structures of Turkey. It separates the west  Anatolian extensional province and the strike-slip induced northwest central Anatolian contractional area in the Anatolian Block. Its southeastern part is generally divided into three branches, namely the Ilıca, Yeniceoba, and Cihanbeyli from north to south, respectively. The right lateral strike-slip Ilıca branch (IB is an approximately 100-km-long fault and it is composed of several segments in a northwest-southeast direction. The slickensides, subsidiary fractures, cataclastic zone, fracture-controlled drainage pattern, right lateral stream deflections, deformation in the Quaternary unit observing in the seismic reflection sections, and seismicity of the region all indicate that the IB is an active right lateral strike-slip fault. The IB has also a regional tectonic importance as a boundary fault between the contractional and the extensional regions in central Anatolia considering that it is the southern limit of the contraction-related structures in the west-southwest of Ankara.

  8. Oblique strike-slip motion off the Southeastern Continental Margin of India: Implication for the separation of Sri Lanka from India

    Science.gov (United States)

    Desa, Maria Ana; Ismaiel, Mohammad; Suresh, Yenne; Krishna, Kolluru Sree

    2018-05-01

    The ocean floor in the Bay of Bengal has evolved after the breakup of India from Antarctica since the Early Cretaceous. Recent geophysical investigations including updated satellite derived gravity map postulated two phases for the tectonic evolution of the Bay of Bengal, the first phase of spreading occurred in the NW-SE direction forming its Western Basin, while the second phase occurred in the N-S direction resulting in its Eastern Basin. Lack of magnetic data along the spreading direction in the Western Basin prompted us to acquire new magnetic data along four tracks (totaling ∼3000 km) to validate the previously identified magnetic anomaly picks. Comparison of the synthetic seafloor spreading model with the observed magnetic anomalies confirmed the presence of Mesozoic anomalies M12n to M0 in the Western Basin. Further, the model suggests that this spreading between India and Antarctica took place with half-spreading rates of 2.7-4.5 cm/yr. The trend of the fracture zones in the Western Basin with respect to that of the Southeastern Continental Margin of India (SCMI) suggests that SCMI is an oblique transform margin with 37° obliquity. Further, the SCMI consists of two oblique transform segments separated by a small rift segment. The strike-slip motion along the SCMI is bounded by the rift segments of the Northeastern Continental Margin of India and the southern margin of Sri Lanka. The margin configuration and fracture zones inferred in its conjugate Western Enderby Basin, East Antarctica helped in inferring three spreading corridors off the SCMI in the Western Basin of the Bay of Bengal. Detailed grid reconstruction models traced the oblique strike-slip motion off the SCMI since M12n time. The strike-slip motion along the short northern transform segment ended by M11n time. The longer transform segment, found east of Sri Lanka lost its obliquity and became a pure oceanic transform fault by M0 time. The eastward propagation of the Africa

  9. Excitation of tsunami by a pure strike-slip earthquake. ; Izu Oshima kinkai earthquake tsunami on Feb. 20, 1990. Yokozure danso jishin ni yoru tsunami no reiki. ; 1990 nen 2 gatsu 20 nichi Izu Oshima kinkai jishin tsunami

    Energy Technology Data Exchange (ETDEWEB)

    Abe, K. (Nippon Dental University, Tokyo (Japan). Niigata Junior College); Okada, M. (Meteorological Research Institute, Tsukuba (Japan))

    1993-06-24

    A numerical experiment was performed to reproduce the tsunami from the Izu-Oshima Kinkai Earthquake which occurred on February 20, 1990, using a tsunami excited by a pure strike-slip fault. An existence of a vertical fault with a length of 15 km and a width of 12 km was hypothesized in the south-north direction on the ocean bottom around the focal region. Then, a tsunami was assumed to have been excited when the fault was given a side-slip movement to create discrepancies of 1 m in the fault. Water level change for one hour after onset of the tsunami was calculated in one-second interval in each unit square with a side length of 1 km over an ocean area of 200 km from east to west and 150 km from north to south centering on the wave source. The results obtained from the calculation were harmonious with tsunami waveforms observed at five stations in the subject region and their spectral analytic results. Reproduced were the two predominant frequencies commonly observed at more than two stations, and difference in predominant cycles that appear according to azimuths of the observation points to the epicenter. These facts endorse the reasonability of the above hypothesis. 9 refs., 11 figs.

  10. Timing of metamorphism of the Lansang gneiss and implications for left-lateral motion along the Mae Ping (Wang Chao) strike-slip fault, Thailand

    Science.gov (United States)

    Palin, R. M.; Searle, M. P.; Morley, C. K.; Charusiri, P.; Horstwood, M. S. A.; Roberts, N. M. W.

    2013-10-01

    The Mae Ping fault (MPF), western Thailand, exhibits dominantly left-lateral strike-slip motion and stretches for >600 km, reportedly branching off the right-lateral Sagaing fault in Myanmar and extending southeast towards Cambodia. Previous studies have suggested that the fault assisted the large-scale extrusion of Sundaland that occurred during the Late Eocene-Early Oligocene, with a geological offset of ˜120-150 km estimated from displaced high-grade gneisses and granites of the Chiang Mai-Lincang belt. Exposures of high-grade orthogneiss in the Lansang National Park, part of this belt, locally contain strong mylonitic textures and are bounded by strike-slip ductile shear zones and brittle faults. Geochronological analysis of monazite from a sample of sheared biotite-K-feldspar orthogneiss suggests two episodes of crystallization, with core regions documenting Th-Pb ages between c. 123 and c. 114 Ma and rim regions documenting a significantly younger age range between c. 45-37 Ma. These data are interpreted to represent possible magmatic protolith emplacement for the Lansang orthogneiss during the Early Cretaceous, with a later episode of metamorphism occurring during the Eocene. Textural relationships provided by in situ analysis suggest that ductile shearing along the MPF occurred during the latter stages of, or after, this metamorphic event. In addition, monazite analyzed from an undeformed garnet-two-mica granite dyke intruding metamorphic units at Bhumipol Lake outside of the Mae Ping shear zone produced a Th-Pb age of 66.2 ± 1.6 Ma. This age is interpreted to date the timing of dyke emplacement, implying that the MPF cuts through earlier formed magmatic and high-grade metamorphic rocks. These new data, when combined with regional mapping and earlier geochronological work, show that neither metamorphism, nor regional cooling, was directly related to strike-slip motion.

  11. Late Quaternary strike-slip along the Taohuala Shan-Ayouqi fault zone and its tectonic implications in the Hexi Corridor and the southern Gobi Alashan, China

    Science.gov (United States)

    Yu, Jing-xing; Zheng, Wen-jun; Zhang, Pei-zhen; Lei, Qi-yun; Wang, Xu-long; Wang, Wei-tao; Li, Xin-nan; Zhang, Ning

    2017-11-01

    The Hexi Corridor and the southern Gobi Alashan are composed of discontinuous a set of active faults with various strikes and slip motions that are located to the north of the northern Tibetan Plateau. Despite growing understanding of the geometry and kinematics of these active faults, the late Quaternary deformation pattern in the Hexi Corridor and the southern Gobi Alashan remains controversial. The active E-W trending Taohuala Shan-Ayouqi fault zone is located in the southern Gobi Alashan. Study of the geometry and nature of slip along this fault zone holds crucial value for better understanding the regional deformation pattern. Field investigations combined with high-resolution imagery show that the Taohuala Shan fault and the E-W trending faults within the Ayouqi fault zone (F2 and F5) are left-lateral strike-slip faults, whereas the NW or WNW-trending faults within the Ayouqi fault zone (F1 and F3) are reverse faults. We collected Optically Stimulated Luminescence (OSL) and cosmogenic exposure age dating samples from offset alluvial fan surfaces, and estimated a vertical slip rate of 0.1-0.3 mm/yr, and a strike-slip rate of 0.14-0.93 mm/yr for the Taohuala Shan fault. Strata revealed in a trench excavated across the major fault (F5) in the Ayouqi fault zone and OSL dating results indicate that the most recent earthquake occurred between ca. 11.05 ± 0.52 ka and ca. 4.06 ± 0.29 ka. The geometry and kinematics of the Taohuala Shan-Ayouqi fault zone enable us to build a deformation pattern for the entire Hexi Corridor and the southern Gobi Alashan, which suggest that this region experiences northeastward oblique extrusion of the northern Tibetan Plateau. These left-lateral strike-slip faults in the region are driven by oblique compression but not associated with the northeastward extension of the Altyn Tagh fault.

  12. Mass Equivalent Pantographs for Synthesis of Balanced Focal Mechanisms

    NARCIS (Netherlands)

    van der Wijk, V.; Lenarcic, Jadran; Merlet, Jean-Pierre

    2016-01-01

    Force balance is an important property in the design of high-speed high precision machinery to reduce base vibrations and also for the design of inherently safe large movable structures. This paper presents the synthesis of inherently balanced overconstrained focal mechanisms with mass equivalent

  13. Silurian to Devonian magmatism, molybdenite mineralization, regional exhumation and brittle strike-slip deformation along the Loch Shin Line, NW Scotland

    OpenAIRE

    Holdsworth, R.; Dempsey, E.; Selby, D.; Darling, James Richard; Feely, M.; Costanzo, A.; Strachan, Robin A; Waters, P.; Finlay, A.J.

    2015-01-01

    The Loch Shin Line is a geological–geophysical lineament associated with a zone of mantle-derived appinites, granites and strike-slip faulting that runs NW–SE across the Moine Nappe, northern Scotland. U–Pb zircon and Re–Os molybdenite dating of the Loch Shin and Grudie plutons, which lie immediately SW of the NW–SE Loch Shin–Strath Fleet fault system, yield c. 427–430 Ma ages that overlap within error. They also coincide with previously obtained U–Pb zircon ages for the Rogart pluton, which ...

  14. The Evolution from Late Miocene West Salton Detachment Faulting to Cross-Cutting Pleistocene Oblique Strike-Slip Faults in the SW Salton Trough, Southern California

    OpenAIRE

    Steely, Alexander N.

    2006-01-01

    Field studies in the southwest Salton Trough between Yaqui Ridge and Borrego Mountain show that the West Salton detachment fault was active during the Pliocene and may have initiated during the latest Miocene. At Yaqui Ridge dominantly east-directed extension is recorded by slickenlines on the NW-striking detachment fault, and shows that the fault is actually a low-angle dextral oblique strike-slip fault. Crustal inheritance is responsible for the position of the fault at Yaqui Ridge, which r...

  15. Structural analysis of S-wave seismics around an urban sinkhole: evidence of enhanced dissolution in a strike-slip fault zone

    Science.gov (United States)

    Wadas, Sonja H.; Tanner, David C.; Polom, Ulrich; Krawczyk, Charlotte M.

    2017-12-01

    In November 2010, a large sinkhole opened up in the urban area of Schmalkalden, Germany. To determine the key factors which benefited the development of this collapse structure and therefore the dissolution, we carried out several shear-wave reflection-seismic profiles around the sinkhole. In the seismic sections we see evidence of the Mesozoic tectonic movement in the form of a NW-SE striking, dextral strike-slip fault, known as the Heßleser Fault, which faulted and fractured the subsurface below the town. The strike-slip faulting created a zone of small blocks ( sinkholes and dissolution-induced depressions. Since the processes are still ongoing, the occurrence of a new sinkhole cannot be ruled out. This case study demonstrates how S-wave seismics can characterize a sinkhole and, together with geological information, can be used to study the processes that result in sinkhole formation, such as a near-surface fault zone located in soluble rocks. The more complex the fault geometry and interaction between faults, the more prone an area is to sinkhole occurrence.

  16. States of stress and slip partitioning in a continental scale strike-slip duplex: Tectonic and magmatic implications by means of finite element modeling

    Science.gov (United States)

    Iturrieta, Pablo Cristián; Hurtado, Daniel E.; Cembrano, José; Stanton-Yonge, Ashley

    2017-09-01

    Orogenic belts at oblique convergent subduction margins accommodate deformation in several trench-parallel domains, one of which is the magmatic arc, commonly regarded as taking up the margin-parallel, strike-slip component. However, the stress state and kinematics of volcanic arcs is more complex than usually recognized, involving first- and second-order faults with distinctive slip senses and mutual interaction. These are usually organized into regional scale strike-slip duplexes, associated with both long-term and short-term heterogeneous deformation and magmatic activity. This is the case of the 1100 km-long Liquiñe-Ofqui Fault System in the Southern Andes, made up of two overlapping margin-parallel master faults joined by several NE-striking second-order faults. We present a finite element model addressing the nature and spatial distribution of stress across and along the volcanic arc in the Southern Andes to understand slip partitioning and the connection between tectonics and magmatism, particularly during the interseismic phase of the subduction earthquake cycle. We correlate the dynamics of the strike-slip duplex with geological, seismic and magma transport evidence documented by previous work, showing consistency between the model and the inferred fault system behavior. Our results show that maximum principal stress orientations are heterogeneously distributed within the continental margin, ranging from 15° to 25° counter-clockwise (with respect to the convergence vector) in the master faults and 10-19° clockwise in the forearc and backarc domains. We calculate the stress tensor ellipticity, indicating simple shearing in the eastern master fault and transpressional stress in the western master fault. Subsidiary faults undergo transtensional-to-extensional stress states. The eastern master fault displays slip rates of 5 to 10 mm/yr, whereas the western and subsidiary faults show slips rates of 1 to 5 mm/yr. Our results endorse that favorably oriented

  17. Rupture model of the 2015 M7.2 Sarez, Central Pamir, earthquake and the importance of strike-slip faulting in the Pamir interior

    Science.gov (United States)

    Metzger, S.; Schurr, B.; Schoene, T.; Zhang, Y.; Sudhaus, H.

    2016-12-01

    The Pamir mountain range, located in the Northwest of the India-Asia collision zone, accommodates approximately one third of the northward advance of the Indian continent at this longitude (i.e. 34 mm/yr) mostly by shortening at its northern thrust system. Geodetic and seismic data sets reveal here a narrow zone of high deformation and M7+ earthquakes of mostly thrust type with some dextral strike-slip faulting observed, too. The Pamir interior shows sinistral strike-slip and normal faulting indicating north-south compression and east-west extension. In this tectonic setting the two largest instrumentally recorded earthquakes, the M7+ 1911 and 2015 earthquake events in the central Pamir occurred with left-lateral shear along a NE-SW rupture plane. We present the co-seismic deformation field of the 2015 earthquake observed by Radar satellite interferometry (InSAR), SAR amplitude offsets and high-rate Global Positioning System (GPS). The InSAR and offset results reveal that the earthquake created a 50 km long surface rupture with maximum left-lateral offsets of more than two meters on a yet unmapped fault trace of the Sarez Karakul Fault System (SKFS). We further derive a distributed slip-model including a thorough model parameter uncertainty study. Using a two-step approach to first find the optimal rupture geometry and then invert for slip on discrete patches, we show that a data-driven patch resolution produces yields a better representation of the near-surface slip and an increased slip precision than a uniform patch approach without increasing the number of parameters and thus calculation time. Our best-fit model yields a sub-vertical fault plane with a strike of N39.5 degrees and a rupture area of 80 x 40 km2 with a maximum slip of 2 meters in the upper 10 km of the crust near the surface rupture. The 1911 and 2015 earthquakes demonstrate the importance of sinistral strike-slip faulting on the SKFS, contributing both to shear between the western and eastern

  18. An Iterative Travel Time Inversion and Waveform Modeling Method to Determine the Crust Structure and Focal Mechanism: Case Study of 2015 Alxa Left Banner Ms5.8 Earthquake

    Science.gov (United States)

    Song, C.; Ge, Z.

    2017-12-01

    The boundary region between Alxa Block and Ordos Block is an area of stress concentration with strong seismicity and frequent small earthquakes. However, the knowledge of this area is limited since only a few seismic stations were deployed in this area. The 2015 Ms5.8 Alxa Left Banner Earthquake on April 15 is the largest one occurred in the surroundings since the 1976 Ms6.2 Bayinmuren Earthquake. Abundant stations built in the northern part of Chinese North-South Seismic Belt recorded this event sequence well within short distance, which provides us a great opportunity to carry out studies. We use these data to obtain a mean 1-D layered velocity structure via iterative inversion based on both travel time and waveform misfits. Then we use the travel time difference between data and synthetic seismograms to relocate the epicenter. Finally we invert the best double-couple focal mechanism and centroid depths of the source. As the result, the source is located at (39.7027° N, 106.4207° E) with a depth of 18 km and Mw 5.28. Nodal plane Ⅰ has strike 86°, dip angle 90° and slip angle -3°, while plane Ⅱ has strike 176°, dip angle 87° and slip angle 180°. Considering the dynamic structure of regional fault zone, we believe this earthquake is caused by a nearly pure left-lateral strike-slip fault with nodal plane Ⅰ being the fault plane. The seismogenic structure is likely to be an E-W striking buried fault nearby. There develops several groups of NE, NEE and E-W striking faults in Jilantai tectonic zone, parts of which have been verified by geophysical investigations. But we still know little about the dynamic nature of them. From our study, the corresponding fault of this event may indicate all groups of faults with same E-W strike has the common character of large-dip left-lateral strike-slip. Moreover, there may be some buried faults being newly born or not found yet. These results could be an important supplement to the future research of seismicity and

  19. Structural analysis of S-wave seismics around an urban sinkhole: evidence of enhanced dissolution in a strike-slip fault zone

    Directory of Open Access Journals (Sweden)

    S. H. Wadas

    2017-12-01

    Full Text Available In November 2010, a large sinkhole opened up in the urban area of Schmalkalden, Germany. To determine the key factors which benefited the development of this collapse structure and therefore the dissolution, we carried out several shear-wave reflection-seismic profiles around the sinkhole. In the seismic sections we see evidence of the Mesozoic tectonic movement in the form of a NW–SE striking, dextral strike-slip fault, known as the Heßleser Fault, which faulted and fractured the subsurface below the town. The strike-slip faulting created a zone of small blocks ( < 100 m in size, around which steep-dipping normal faults, reverse faults and a dense fracture network serve as fluid pathways for the artesian-confined groundwater. The faults also acted as barriers for horizontal groundwater flow perpendicular to the fault planes. Instead groundwater flows along the faults which serve as conduits and forms cavities in the Permian deposits below ca. 60 m depth. Mass movements and the resulting cavities lead to the formation of sinkholes and dissolution-induced depressions. Since the processes are still ongoing, the occurrence of a new sinkhole cannot be ruled out. This case study demonstrates how S-wave seismics can characterize a sinkhole and, together with geological information, can be used to study the processes that result in sinkhole formation, such as a near-surface fault zone located in soluble rocks. The more complex the fault geometry and interaction between faults, the more prone an area is to sinkhole occurrence.

  20. The last interglacial period at Guantanamo Bay, Cuba and an estimate of late Quaternary tectonic uplift rate in a strike-slip regime

    Science.gov (United States)

    Schweig, E. S.; Muhs, D. R.; Simmons, K. R.; Halley, R. B.

    2015-12-01

    Guantanamo Bay, Cuba is an area dominated by a strike-slip tectonic regime and is therefore expected to have very low Quaternary uplift rates. We tested this hypothesis by study of an unusually well preserved emergent reef terrace around the bay. Up to 12 m of unaltered, growth-position reef corals are exposed at about 40 sections examined around ˜40 km of coastline. Maximum reef elevations in the protected, inner part of the bay are ˜11-12 m, whereas outer-coast shoreline angles of wave-cut benches are as high as ˜14 m. Fifty uranium-series analyses of unrecrystallized corals from six localities yield ages ranging from ˜134 ka to ˜115 ka, when adjusted for small biases due to slightly elevated initial 234U/238U values. Thus, ages of corals correlate this reef to the peak of the last interglacial period, marine isotope stage (MIS) 5.5. Previously, we dated the Key Largo Limestone to the same high-sea stand in the tectonically stable Florida Keys. Estimates of paleo-sea level during MIS 5.5 in the Florida Keys are ~6.6 to 8.3 m above present. Assuming a similar paleo-sea level in Cuba, this yields a long-term tectonic uplift rate of 0.04-0.06 m/ka over the past ~120 ka. This estimate supports the hypothesis that the tectonic uplift rate should be low in this strike-slip regime. Nevertheless, on the southeast coast of Cuba, east of our study area, we have observed flights of multiple marine terraces, suggesting either (1) a higher uplift rate or (2) an unusually well-preserved record of pre-MIS 5.5 terraces not observed at Guantanamo Bay.

  1. 'Extra-regional' strike-slip fault systems in Chile and Alaska: the North Pacific Rim orogenic Stream vs. Beck's Buttress

    Science.gov (United States)

    Redfield, T. F.; Scholl, D. W.; Fitzgerald, P. G.

    2010-12-01

    The ~2000 km long Denali Fault System (DFS) of Alaska is an example of an extra-regional strike-slip fault system that terminates in a zone of widely-distributed deformation. The ~1200 km long Liquiñe-Ofqui Fault Zone (LOFZ) of Patagonia (southern Chile) is another. Both systems are active, having undergone large-magnitude seismic rupture is 2002 (DFS) and 2007 (LOFZ). Both systems appear to be long-lived: the DFS juxtaposes terranes that docked in at least early Tertiary time, whilst the central LOFZ appears to also record early Tertiary or Mesozoic deformation. Both fault systems comprise a relatively well-defined central zone where individual fault traces can be identified from topographic features or zones of deformed rock. In both cases the proximal and distal traces are much more diffuse tributary and distributary systems of individual, branching fault traces. However, since their inception the DFS and LOFZ have followed very different evolutionary paths. Copious Alaskan paleomagnetic data are consistent with vertical axis small block rotation, long-distance latitudinal translation, and a recently-postulated tectonic extrusion towards a distributary of subordinate faults that branch outward towards the Aleution subduction zone (the North Pacific Rim orogenic Stream; see Redfield et al., 2007). Paleomagnetic data from the LOFZ region are consistent with small block rotation but preclude statistically-significant latitudinal transport. Limited field data from the southernmost LOFZ suggest that high-angle normal and reverse faults dominate over oblique to strike-slip structures. Rather than the high-angle oblique 'slivering regime' of the southeasternmost DFS, the initiation of the LOFZ appears to occur across a 50 to 100 km wide zone of brittly-deformed granitic and gneissic rock characterized by bulk compression and vertical pathways of exhumation. In both cases, relative plate motions are consistent with the hypothetical style, and degree, of offset, leading

  2. Palaeopermeability anisotropies of a strike-slip fault damage zone: 3D Insights of quantitative fluid flow from µCT analysis.

    Science.gov (United States)

    Gomila, R.; Arancibia, G.; Nehler, M.; Bracke, R.; Morata, D.

    2017-12-01

    Fault zones and their related structural permeability are a key aspect in the migration of fluids through the continental crust. Therefore, the estimation of the hydraulic properties (palaeopermeability conditions; k) and the spatial distribution of the fracture mesh within the damage zone (DZ) are critical in the assessment of fault zones behavior for fluids. The study of the real spatial distribution of the veinlets of the fracture mesh (3D), feasible with the use of µCT analyses, is a first order factor to unravel both, the real structural permeability conditions of a fault-zone, and the validation of previous (and classical) estimations made in 2D analyses in thin-sections. This work shows the results of a fault-related fracture mesh and its 3D spatial distribution in the damage-zone of the Jorgillo Fault (JF), an ancient subvertical left-lateral strike-slip fault exposed in the Atacama Fault System in northern Chile. The JF is a ca. 20 km long NNW-striking strike-slip fault with sinistral displacement of ca. 4 km. The methodology consisted of drilling 5 mm vertically oriented plugs at several locations within the JF damage zone. Each specimen was scanned with an X-Ray µCT scanner, to assess the fracture mesh, with a voxel resolution of ca. 4.5 µm in the 3D reconstructed data. Tensor permeability modeling, using Lattice-Boltzmann Method, through the segmented microfracture mesh show GMkmin (geometric mean values) of 2.1x10-12 and 9.8x10-13 m2, and GMkmax of 6.4x10-12 and 2.1x10-12 m2. A high degree of anisotropy of the DZ permeability tensor both sides of the JF (eastern and western side, respectively) is observed, where the k values in the kmax plane are 2.4 and 1.9 times higher than the kmin direction at the time of fracture sealing. This style of anisotropy is consistent with the obtained for bedded sandstones supporting the idea that damage zones have an analogous effect - but vertically orientated - on bulk permeability (in low porosity rocks) as

  3. Near N-S paleo-extension in the western Deccan region, India: Does it link strike-slip tectonics with India-Seychelles rifting?

    Science.gov (United States)

    Misra, Achyuta Ayan; Bhattacharya, Gourab; Mukherjee, Soumyajit; Bose, Narayan

    2014-09-01

    This is the first detailed report and analyses of deformation from the W part of the Deccan large igneous province (DLIP), Maharashtra, India. This deformation, related to the India-Seychelles rifting during Late Cretaceous-Early Paleocene, was studied, and the paleostress tensors were deduced. Near N-S trending shear zones, lineaments, and faults were already reported without significant detail. An E-W extension was envisaged by the previous workers to explain the India-Seychelles rift at ~64 Ma. The direction of extension, however, does not match with their N-S brittle shear zones and also those faults (sub-vertical, ~NE-SW/~NW-SE, and few ~N-S) we report and emphasize in this work. Slickenside-bearing fault planes, brittle shear zones, and extension fractures in meso-scale enabled us to estimate the paleostress tensors (directions and relative magnitudes). The field study was complemented by remote sensing lineament analyses to map dykes and shear zones. Dykes emplaced along pre-existing ~N-S to ~NE-SW/~NW-SE shears/fractures. This information was used to derive regional paleostress trends. A ~NW-SE/NE-SW minimum compressive stress in the oldest Kalsubai Subgroup and a ~N-S direction for the younger Lonavala, Wai, and Salsette Subgroups were deciphered. Thus, a ~NW/NE to ~N-S extension is put forward that refutes the popular view of E-W India-Seychelles extension. Paleostress analyses indicate that this is an oblique rifted margin. Field criteria suggest only ~NE-SW and ~NW-SE, with some ~N-S strike-slip faults/brittle shear zones. We refer this deformation zone as the "Western Deccan Strike-slip Zone" (WDSZ). The observed deformation was matched with offshore tectonics deciphered mainly from faults interpreted on seismic profiles and from magnetic seafloor spreading anomalies. These geophysical findings too indicate oblique rifting in this part of the W Indian passive margin. We argue that the Seychelles microcontinent separated from India only after much of

  4. The geometry of the active strike-slip El Tigre Fault, Precordillera of San Juan, Central-Western Argentina: integrating resistivity surveys with structural and geomorphological data

    Science.gov (United States)

    Fazzito, Sabrina Y.; Cortés, José M.; Rapalini, Augusto E.; Terrizzano, Carla M.

    2013-07-01

    The geometry and related geomorphological features of the right-lateral strike-slip El Tigre Fault, one of the main morphostructural discontinuities in the Central-Western Precordillera of Argentina, were investigated. Achievements of this survey include: recognition of structural and geometrical discontinuities along the fault trace, identification and classification of landforms associated with local transpressional and transtensional sectors, observation of significant changes in the fault strike and detection of right and left bends of different wavelength. In the Central Segment of the El Tigre Fault, 2D electrical resistivity tomography surveys were carried out across the fault zone. The resistivity imaging permitted to infer the orientation of the main fault surface, the presence of blind fault branches along the fault zone, tectonic tilting of the Quaternary sedimentary cover, subsurface structure of pressure ridges and depth to the water table. Based on this information, it is possible to characterize the El Tigre Fault also as an important hydro-geological barrier. Our survey shows that the main fault surface changes along different segments from a high-angle to a subvertical setting whilst the vertical-slip component is either reverse or normal, depending on the local transpressive or transtensive regime induced by major bends along the trace. These local variations are expressed as sections of a few kilometres in length with relatively homogeneous behaviour and frequently separated by oblique or transversal structures.

  5. Determination of Focal Mechanisms of Non-Volcanic Tremors Based on S-Wave Polarization Data Corrected for the Effects of Anisotropy

    Science.gov (United States)

    Imanishi, K.; Uchide, T.; Takeda, N.

    2014-12-01

    We propose a method to determine focal mechanisms of non-volcanic tremors (NVTs) based on S-wave polarization angles. The successful retrieval of polarization angles in low S/N tremor signals owes much to the observation that NVTs propagate slowly and therefore they do not change their location immediately. This feature of NVTs enables us to use a longer window to compute a polarization angle (e.g., one minute or longer), resulting in a stack of particle motions. Following Zhang and Schwartz (1994), we first correct for the splitting effect to recover the source polarization angle (anisotropy-corrected angle). This is a key step, because shear-wave splitting distorts the particle motion excited by a seismic source. We then determine the best double-couple solution using anisotropy-corrected angles of multiple stations. The present method was applied to a tremor sequence at Kii Peninsula, southwest Japan, which occurred at the beginning of April 2013. A standard splitting and polarization analysis were subject to a one-minute-long moving window to determine the splitting parameters as well as anisotropy-corrected angles. A grid search approach was performed at each hour to determine the best double-couple solution satisfying one-hour average polarization angles. Most solutions show NW-dipping low-angle planes consistent with the plate boundary or SE-dipping high-angle planes. Because of 180 degrees ambiguity in polarization angles, the present method alone cannot distinguish compressional quadrant from dilatational one. Together with the observation of very low-frequency earthquakes near the present study area (Ito et al., 2007), it is reasonable to consider that they represent shear slip on low-angle thrust faults. It is also noted that some of solutions contain strike-slip component. Acknowledgements: Seismograph stations used in this study include permanent stations operated by NIED (Hi-net), JMA, Earthquake Research Institute, together with Geological Survey of

  6. Mechanical design and analysis of focal plate for gravity deformation

    Science.gov (United States)

    Wang, Jianping; Chu, Jiaru; Hu, Hongzhuan; Li, Kexuan; Zhou, Zengxiang

    2014-07-01

    The surface accuracy of astronomical telescope focal plate is a key indicator to precision stellar observation. To conduct accurate deformation measurement for focal plate in different status, a 6-DOF hexapod platform was used for attitude adjustment. For the small adjustment range of a classic 6-DOF hexapod platform, an improved structural arrangement method was proposed in the paper to achieve ultimate adjustment of the focal plate in horizontal and vertical direction. To validate the feasibility of this method, an angle change model which used ball hinge was set up for the movement and base plate. Simulation results in MATLAB suggested that the ball hinge angle change of movement and base plate is within the range of the limiting angle in the process of the platform plate adjusting to ultimate attitude. The proposed method has some guiding significance for accurate surface measurement of focal plate.

  7. Focal mechanism determination for voIcanic microearthquakes

    Directory of Open Access Journals (Sweden)

    G. De Natale

    1994-06-01

    Full Text Available Classical methods to infer focal mechanisms from first P wave motions are of limited use for the analysis of small magnitude events occurring in volcanic areas, due to structure complexity. This work presents an alternative way to compute focal mechanisms of earthquakes in volcanic areas, based on a Bayesian approach. The probability density on the whole space spanned by source parameters is graphically represented, by a method originally due to Bernard and Zollo (1989. The data used to infer the probability density function can be of various kinds, like P wave polarities, S wave polarizations and S/P direct wave amplitude ratios. S wave polarizations are left practically unchanged by smooth variations of velocity, and are only sensitive to strong discontinuities and/or seismic anisotropy. S/P amplitude ratios of direct waves are also good observables, not very sensitive to frequency independent amplification effects. They are still affected by differential S-P anelastic attenuation, although to a much lesser extent than absolute S and P amplitudes. In fact, the use of complete waveforms is not desiderable in volcanic areas because wave amplitudes may be strongly biased by not well known path and site effects, mainly for non direct waves which are most affected by medium heterogeneities. Such unmodeled elastic and anelastic features of the medium can be traded off for source characteristics, leading to bad results. The use of the probabilistic approach, and the seloction of robust observables, allow us to solve many problems of classical methods. The determination of the whole probability density on the parameter space visualizes all the information contained in the data set, checking completely the goodness of the solution, and its univoqueness. Furthermore, the use of different kinds of robust data sets helps to constrain the solution, and to minimize the influence of unmodeled medium heterogeneities. In the present method, it is possible to

  8. A Comparison of Geodetic and Geologic Rates Prior to Large Strike-Slip Earthquakes: A Diversity of Earthquake-Cycle Behaviors?

    Science.gov (United States)

    Dolan, James F.; Meade, Brendan J.

    2017-12-01

    Comparison of preevent geodetic and geologic rates in three large-magnitude (Mw = 7.6-7.9) strike-slip earthquakes reveals a wide range of behaviors. Specifically, geodetic rates of 26-28 mm/yr for the North Anatolian fault along the 1999 MW = 7.6 Izmit rupture are ˜40% faster than Holocene geologic rates. In contrast, geodetic rates of ˜6-8 mm/yr along the Denali fault prior to the 2002 MW = 7.9 Denali earthquake are only approximately half as fast as the latest Pleistocene-Holocene geologic rate of ˜12 mm/yr. In the third example where a sufficiently long pre-earthquake geodetic time series exists, the geodetic and geologic rates along the 2001 MW = 7.8 Kokoxili rupture on the Kunlun fault are approximately equal at ˜11 mm/yr. These results are not readily explicable with extant earthquake-cycle modeling, suggesting that they may instead be due to some combination of regional kinematic fault interactions, temporal variations in the strength of lithospheric-scale shear zones, and/or variations in local relative plate motion rate. Whatever the exact causes of these variable behaviors, these observations indicate that either the ratio of geodetic to geologic rates before an earthquake may not be diagnostic of the time to the next earthquake, as predicted by many rheologically based geodynamic models of earthquake-cycle behavior, or different behaviors characterize different fault systems in a manner that is not yet understood or predictable.

  9. Seismically-triggered soft-sediment deformation structures close to a major strike-slip fault system in the Eastern Alps (Hirlatz cave, Austria)

    Science.gov (United States)

    Salomon, Martina Lan; Grasemann, Bernhard; Plan, Lukas; Gier, Susanne; Schöpfer, Martin P. J.

    2018-05-01

    We investigate episodic soft-sediment deformation structures cross-cut by normal faults preserved in unlithified finely laminated calcite rich sediments in the Hirlatz cave in the Northern Calcareous Alps (Austria). These sediments comprise varve-like alternations of brighter carbonate/quartz rich layers, and darker clay mineral rich layers. The deformed sediments contain abundant millimeter to centimeter-scale soft-sediment structures (load casts, ball-and-pillow structures), sheet slumps (thrust faults and folds), erosive channels filled with slides and chaotic slumps. After deposition and soft-sediment deformation normal faults developed within the entire sedimentary succession, an event that probably correlates with an offset of c. 10 cm of the passage wall above the outcrop. Our major conclusions are: (i) The sediments have a glacial origin and were deposited in the Hirlatz cave under phreatic fluvio-lacustrine conditions. The deposition and the soft-sediment deformation occurred most likely during the last glaciation (i.e. around 25 ka ago); (ii) The liquefaction and formation of the soft-sediment structures in water-saturated stratified layers was triggered by episodic seismic events; (iii) The internally deformed sediments were later displaced by normal faults; (iv) A possible source for the seismic events is the active sinistral Salzach-Ennstal-Mariazeller-Puchberger (SEMP) strike-slip fault which is located about 10 km south of the outcrop and plays a major role in accommodating the extrusion of the Eastern Alps towards the Pannonian Basin. To our knowledge, the described structures are the first report of liquefaction and seismically induced soft-sediment deformations in Quaternary sediments in the Eastern Alps.

  10. 3D deformation in strike-slip systems: Analogue modelling and numerical restoration Deformación 3D en sistemas de rumbo: modelación analógica y restauración numérica

    Directory of Open Access Journals (Sweden)

    Daniel González

    2012-05-01

    Full Text Available Regional and local strike-slip systems in Chile are complex and pose interesting questions, such as the interaction between strike-slip and reverse faults, how they evolve, and the relationship between shortening, rotation and uplift. Within this context, we developed a new analytical method based on analogue and numerical modelling applied to 3D, pure and transtensional-transpressional strike-slip systems. Analogue modelling results indicate that in restraining stepovers of strike-slip fault systems, where antiformal pop-up structures are usually formed, pre-existent basement structures with a high angle to the main strike-slip fault will generate a higher rotation of blocks. However, when these structures are oriented at a high angle with respect to the main stress convergence vector, the rotation will be less and therefore a higher tendency to uplift will be produced. These results were applied to NW- and SE-striking basement faults oblique to N-S mega-thrust faults in central Chile (32°-35°S, for which we propose a simultaneous development based on the analogue model results. Moreover, we propose that strike-slip movement occurred on thrust faults in central Chile. Furthermore, we performed a numerical restoration of an analogue experiment which modeled a pure strike-slip system, and concluded that the restoration is very sensitive to shortening data as well as to rotational data. These results are extremely important for future numerical and regional analysis of strike-slip systems.Los sistemas de rumbo regionales y locales en Chile son complejos y plantean interesantes preguntas, tales como la interacción entre fallas de rumbo y fallas inversas, cómo evolucionan ellas, y la relación entre acortamiento, rotación y alzamiento. En este contexto, desarrollamos un nuevo método analítico basado en modelamiento analógico y numérico de sistemas de rumbo de cizalle puro y sistemas transpresionales-trantensionales en 3D. Los resultados del

  11. Focal mechanisms and tidal modulation for tectonic tremors in Taiwan

    Science.gov (United States)

    Ide, S.; Yabe, S.; Tai, H. J.; Chen, K. H.

    2015-12-01

    Tectonic tremors in Taiwan have been discovered beneath the southern Central Range, but their hosting structure has been unknown. Here we constrain the focal mechanism of underground deformation related to tremors, using moment tensor inversion in the very low frequency band and tidal stress analysis. Three types of seismic data are used for two analysis steps: detection of tremors and the moment tensor inversion. Short-period seismograms from CWBSN are used for tremor detection. Broadband seismograms from BATS and the TAIGER project are used for both steps. About 1000 tremors were detected using an envelope correlation method in the high frequency band (2-8 Hz). Broadband seismograms are stacked relative to the tremor timing, and inverted for a moment tensor in the low frequency band (0.02-0.05 Hz). The best solution was obtained at 32 km depth, as a double-couple consistent with a low-angle thrust fault dipping to the east-southeast, or a high-angle thrust with a south-southwest strike. Almost all tremors occur when tidal shear stress is positive and normal stress is negative (clamping). Since the clamping stress is high for a high-angle thrust fault, the low-angle thrust fault is more likely to be the fault plane. Tremor rate increases non-linearly with increasing shear stress, suggesting a velocity strengthening friction law. The high tidal sensitivity is inconsistent with horizontal slip motion suggested by previous studies, and normal faults that dominates regional shallow earthquakes. Our results favor thrust slip on a low-angle fault dipping to the east-southeast, consistent with the subduction of the Eurasian plate. The tremor region is characterized by a deep thermal anomaly with decrease normal stress. This region has also experienced enough subduction to produce metamorphic fluids. A large amount of fluid and low vertical stress may explain the high tidal sensitivity.

  12. Hematite (U-Th)/He thermochronometry constrains intraplate strike-slip faulting on the Kuh-e-Faghan Fault, central Iran

    Science.gov (United States)

    Calzolari, Gabriele; Rossetti, Federico; Ault, Alexis K.; Lucci, Federico; Olivetti, Valerio; Nozaem, Reza

    2018-03-01

    The Kuh-e-Faghan strike-slip fault system (KFF), located to the northern edge of the Lut Block in central Iran, developed through a Neogene-Quaternary pulsed history of eastward fault propagation and fault-related exhumation. This system is a consequence of the residual stresses transmitted from the Arabia-Eurasia convergent plate boundary. Here we integrate structural and textural analysis with new and previously published apatite fission-track (AFT) and apatite (U-Th)/He (apatite He) results, chlorite thermomentry, and hematite (U-Th)/He data from hematite-coated brittle fault surfaces to constrain the timing of tectonic activity and refine patterns of late Miocene-Pliocene burial and exhumation associated with the propagation of the KFF. Twenty-nine hematite (U-Th)/He (hematite He) dates from three striated hematite coated slip surfaces from the KFF fault core and damage zone yield individual dates from 12-2 Ma. Petrographic analysis and chlorite thermometry of a polyphase, fossil fluid system in the KFF fault core document that fluid circulation and mineralization transitioned from a closed system characterized by pressure solution and calcite growth to an open system characterized by hot hydrothermal (T = 239 ± 10 °C) fluids and hematite formation. Hematite microtextures and grain size analysis reveal primary and secondary syntectonic hematite fabrics, no evidence of hematite comminution and similar hematite He closure temperatures ( 60-85 °C) in each sample. Integration of these results with thermal history modeling of AFT and apatite He data shows that KFF activity in the late Miocene is characterized by an early stage of fault nucleation, fluid circulation, hematite mineralization, and eastward propagation not associated with vertical movement that lasted from 12 to 7 Ma. Hematite He, AFT, and apatite He data track a second phase of fault system activity involving fault-related exhumation initiating at 7 Ma and continuing until present time. Our new data

  13. Middle Pleistocene infill of Hinkley Valley by Mojave River sediment and associated lake sediment: Depositional architecture and deformation by strike-slip faults

    Science.gov (United States)

    Miller, David; Haddon, Elizabeth; Langenheim, Victoria; Cyr, Andrew J.; Wan, Elmira; Walkup, Laura; Starratt, Scott W.

    2018-01-01

    avulsed through the valley, rather than continuing toward Lake Manix, during the late Pleistocene. Two dextral strike-slip fault zones, the Lockhart and the Mt. General, fold and displace the distinctive stratigraphic units, as well as surficial late Pleistocene and Holocene deposits. The sedimentary architecture and the two fault zones provide a framework for evaluating groundwater flow in Hinkley Valley.

  14. Constraints on the rheology of the lower crust in a strike-slip plate boundary: evidence from the San Quintín xenoliths, Baja California, Mexico

    Science.gov (United States)

    van der Werf, Thomas; Chatzaras, Vasileios; Marcel Kriegsman, Leo; Kronenberg, Andreas; Tikoff, Basil; Drury, Martyn R.

    2017-12-01

    The rheology of lower crust and its transient behavior in active strike-slip plate boundaries remain poorly understood. To address this issue, we analyzed a suite of granulite and lherzolite xenoliths from the upper Pleistocene-Holocene San Quintín volcanic field of northern Baja California, Mexico. The San Quintín volcanic field is located 20 km east of the Baja California shear zone, which accommodates the relative movement between the Pacific plate and Baja California microplate. The development of a strong foliation in both the mafic granulites and lherzolites, suggests that a lithospheric-scale shear zone exists beneath the San Quintín volcanic field. Combining microstructural observations, geothermometry, and phase equilibria modeling, we estimated that crystal-plastic deformation took place at temperatures of 750-890 °C and pressures of 400-560 MPa, corresponding to 15-22 km depth. A hot crustal geotherm of 40 ° C km-1 is required to explain the estimated deformation conditions. Infrared spectroscopy shows that plagioclase in the mafic granulites is relatively dry. Microstructures are interpreted to show that deformation in both the uppermost lower crust and upper mantle was accommodated by a combination of dislocation creep and grain-size-sensitive creep. Recrystallized grain size paleopiezometry yields low differential stresses of 12-33 and 17 MPa for plagioclase and olivine, respectively. The lower range of stresses (12-17 MPa) in the mafic granulite and lherzolite xenoliths is interpreted to be associated with transient deformation under decreasing stress conditions, following an event of stress increase. Using flow laws for dry plagioclase, we estimated a low viscosity of 1.1-1.3×1020 Pa ṡ s for the high temperature conditions (890 °C) in the lower crust. Significantly lower viscosities in the range of 1016-1019 Pa ṡ s, were estimated using flow laws for wet plagioclase. The shallow upper mantle has a low viscosity of 5.7×1019 Pa ṡ s

  15. Seismic attribute detection of faults and fluid pathways within an active strike-slip shear zone: New insights from high-resolution 3D P-Cable™ seismic data along the Hosgri Fault, offshore California

    Science.gov (United States)

    Kluesner, Jared W.; Brothers, Daniel

    2016-01-01

    Poststack data conditioning and neural-network seismic attribute workflows are used to detect and visualize faulting and fluid migration pathways within a 13.7 km2 13.7 km2 3D P-Cable™ seismic volume located along the Hosgri Fault Zone offshore central California. The high-resolution 3D volume used in this study was collected in 2012 as part of Pacific Gas and Electric’s Central California Seismic Imaging Project. Three-dimensional seismic reflection data were acquired using a triple-plate boomer source (1.75 kJ) and a short-offset, 14-streamer, P-Cable system. The high-resolution seismic data were processed into a prestack time-migrated 3D volume and publically released in 2014. Postprocessing, we employed dip-steering (dip and azimuth) and structural filtering to enhance laterally continuous events and remove random noise and acquisition artifacts. In addition, the structural filtering was used to enhance laterally continuous edges, such as faults. Following data conditioning, neural-network based meta-attribute workflows were used to detect and visualize faults and probable fluid-migration pathways within the 3D seismic volume. The workflow used in this study clearly illustrates the utility of advanced attribute analysis applied to high-resolution 3D P-Cable data. For example, results from the fault attribute workflow reveal a network of splayed and convergent fault strands within an approximately 1.3 km wide shear zone that is characterized by distinctive sections of transpressional and transtensional dominance. Neural-network chimney attribute calculations indicate that fluids are concentrated along discrete faults in the transtensional zones, but appear to be more broadly distributed amongst fault bounded anticlines and structurally controlled traps in the transpressional zones. These results provide high-resolution, 3D constraints on the relationships between strike-slip fault mechanics, substrate deformation, and fluid migration along an active

  16. Focal plane mechanical design of the NISP/Euclid instrument

    Science.gov (United States)

    Bonnefoi, Anne; Bon, William; Niclas, Mathieu; Solheim, Bjarte G. B.; Torvanger, Oyvind; Schistad, Robert; Foulon, Benjamin; Garcia, José; Vives, Sébastien

    2016-07-01

    Currently in phase C, the Euclid mission selected by ESA in the Cosmic Vision program is dedicated to understand dark energy and dark matter. NISP (standing for Near Infrared Spectro-Photometer) is one of the two instruments of the mission. NISP will combine a photometer and a spectrometer working in the near-IR (0.9-2 microns). Its detection subsystem (called NI-DS) is based on a mosaic of 16 IR detectors cooled down to 90K which are supported by a molybdenum plate. The front-end readout electronics (working at 130K) are supported by another structure in Aluminum. The NI-DS is mounted on the rest of the instrument thanks to a panel in Silicon Carbide (SiC). Finally an optical baffle in Titanium will prevent the rogue light to reach the detectors. On top of the complexity due to the wide range of temperatures and the various materials imposed at the interfaces; the NI-DS has also to incorporate an internal adjustment capability of the position of the focal plane in tip/tilt and focus. This article will present current status of the development of the detection system of NISP.

  17. Analysis of the impact of fault mechanism radiation patterns on macroseismic fields in the epicentral area of 1998 and 2004 Krn Mountains earthquakes (NW Slovenia).

    Science.gov (United States)

    Gosar, Andrej

    2014-01-01

    Two moderate magnitude (Mw = 5.6 and 5.2) earthquakes in Krn Mountains occurred in 1998 and 2004 which had maximum intensity VII-VIII and VI-VII EMS-98, respectively. Comparison of both macroseismic fields showed unexpected differences in the epicentral area which cannot be explained by site effects. Considerably, different distribution of the highest intensities can be noticed with respect to the strike of the seismogenic fault and in some localities even higher intensities have been estimated for the smaller earthquake. Although hypocentres of both earthquakes were only 2 km apart and were located on the same seismogenic Ravne fault, their focal mechanisms showed a slight difference: almost pure dextral strike-slip for the first event and a strike-slip with small reverse component on a steep fault plane for the second one. Seismotectonically the difference is explained as an active growth of the Ravne fault at its NW end. The radiation patterns of both events were studied to explain their possible impact on the observed variations in macroseismic fields and damage distribution. Radiation amplitude lobes were computed for three orthogonal directions: radial P, SV, and SH. The highest intensities of both earthquakes were systematically observed in directions of four (1998) or two (2004) large amplitude lobes in SH component (which corresponds mainly to Love waves), which have significantly different orientation for both events. On the other hand, radial P direction, which is almost purely symmetrical for the strike-slip mechanism of 1998 event, showed for the 2004 event that its small reverse component of movement has resulted in a very pronounced amplitude lobe in SW direction where two settlements are located which expressed higher intensities in the case of the 2004 event with respect to the 1998 one. Although both macroseismic fields are very complex due to influences of multiple earthquakes, retrofitting activity after 1998, site effects, and sparse

  18. Focal mechanism of seismic events with a dipolar component

    Directory of Open Access Journals (Sweden)

    R. Console

    1995-06-01

    Full Text Available In this paper we model the geometry of a seismic source as a dislocation occurring on an elemental flat fault in an arbitrary direction with respect to the fault plane. This implies the use of a fourth parameter in addition to the three usual ones describing a simple double couple mechanism. We applied the radiation pattern obtained from the theory to a computer code written for the inversion of the observation data (amplitudes and polarities of the first onsets recorded by a network of stations. It allows the determination of the fault mechanism gener- alized in the above mentioned way. The computer code was verified on synthetic data and then applied to real data recorded by the seismic network operated by the Ente Nazionale per l'Energia Elettrica (ENEL, monitoring the geothermal field of Larderello. The experimental data show that for some events the source mechanism exhibits a significant dipolar component. However, due to the high standard deviation of the amplitude data, F-test applied to the results of the analysis shows that only for two events the confidence level for the general- ized model exceeds 90%.

  19. Substrate, focal adhesions, and actin filaments: a mechanical unit with a weak spot for mechanosensitive proteins

    International Nuclear Information System (INIS)

    Kirchenbuechler, David; Born, Simone; Kirchgessner, Norbert; Houben, Sebastian; Hoffmann, Bernd; Merkel, Rudolf

    2010-01-01

    Mechanosensing is a vital prerequisite for dynamic remodeling of focal adhesions and cytoskeletal structures upon substrate deformation. For example, tissue formation, directed cell orientation or cell differentiation are regulated by such mechanosensing processes. Focal adhesions and the actin cytoskeleton are believed to be involved in these processes, but where mechanosensing molecules are located and how elastic substrate, focal adhesions and the cytoskeleton couple with each other upon substrate deformation still remains obscure. To approach these questions we have developed a sensitive method to apply defined spatially decaying deformation fields to cells cultivated on ultrasoft elastic substrates and to accurately quantify the resulting displacements of the actin cytoskeleton, focal adhesions, as well as the substrate. Displacement fields were recorded in live cell microscopy by tracking either signals from fluorescent proteins or marker particles in the substrate. As model cell type we used myofibroblasts. These cells are characterized by highly stable adhesion and force generating structures but are still able to detect mechanical signals with high sensitivity. We found a rigid connection between substrate and focal adhesions. Furthermore, stress fibers were found to be barely extendable almost over their whole lengths. Plastic deformation took place only at the very ends of actin filaments close to focal adhesions. As a result, this area became elongated without extension of existing actin filaments by polymerization. Both ends of the stress fibers were mechanically coupled with detectable plastic deformations on either site. Interestingly, traction force dependent substrate deformation fields remained mostly unaffected even when stress fiber elongations were released. These data argue for a location of mechanosensing proteins at the ends of actin stress fibers and describe, except for these domains, the whole system to be relatively rigid for tensile

  20. Fast characterization of moment magnitude and focal mechanism in the context of tsunami warning in the NEAM region : W-phase and PDFM2 algorithms.

    Science.gov (United States)

    Schindelé, François; Roch, Julien; Duperray, Pierre; Reymond, Dominique

    2016-04-01

    Over past centuries, several large earthquakes (Mw ≥ 7.5) have been reported in the North East Atlantic and Mediterranenan sea (NEAM) region. Most of the tsunami potential seismic sources in the NEAM region, however, are in a magnitude range of 6.5 ≤ Mw ≤ 7.5 (e.g. tsunami triggered by the earthquake of Boumerdes in 2003 of Mw = 6.9). The CENALT (CENtre d'ALerte aux Tsunamis) in operation since 2012 as the French National Tsunami Warning Centre (NTWC) and Candidate Tsunami Service Provider (CTSP) has to issue warning messages within 15 minutes of the earthquake origin time. The warning level is currently based on a decision matrix depending on the magnitude, and the location of the hypocenter. Two seismic source inversion methods are implemented at CENALT: the W-phase algorithm, based on the so-called W-phase and PDFM2 algorithm , based on the surface waves and first P wave motions. They both give accurate moment magnitude and focal magnitude respectively in 10 min and 20 min. The results of the Mw magnitude, focal depth and type of fault (reverse, normal, strike-slip) are the most relevant parameters used to issue tsunami warnings. In this context, we assess the W-phase and PDFM2 methods with 29 events of magnitude Mw ≥ 5.8 for the period 2010-2015 in the NEAM region. Results with 10 and 20 min for the W-phase algorithm and with 20 and 30 min for the PDFM2 algorithm are compared to the Global Centroid Moment Tensor catalog. The W-phase and PDFM2 methods gives accurate results respectively in 10 min and 20 min. This work is funded by project ASTARTE -- Assessment, Strategy And Risk Reduction for Tsunamis in Europe - FP7-ENV2013 6.4-3, Grant 603839

  1. Theory of the mechanical response of focal adhesions to shear flow

    International Nuclear Information System (INIS)

    Biton, Y Y; Safran, S A

    2010-01-01

    The response of cells to shear flow is primarily determined by the asymmetry of the external forces and moments that are sensed by each member of a focal adhesion pair connected by a contractile stress fiber. In the theory presented here, we suggest a physical model in which each member of such a pair of focal adhesions is treated as an elastic body subject to both a myosin-activated contractile force and the shear stress induced by the external flow. The elastic response of a focal adhesion complex is much faster than the active cellular processes that determine the size of the associated focal adhesions and the direction of the complex relative to the imposed flow. Therefore, the complex attains its mechanical equilibrium configuration which may change because of the cellular activity. Our theory is based on the experimental observation that focal adhesions modulate their cross-sectional area in order to attain an optimal shear. Using this assumption, our elastic model shows that such a complex can passively change its orientation to align parallel to the direction of the flow.

  2. Comparing the mechanical influence of vinculin, focal adhesion kinase and p53 in mouse embryonic fibroblasts

    International Nuclear Information System (INIS)

    Klemm, Anna H.; Diez, Gerold; Alonso, Jose-Luis; Goldmann, Wolfgang H.

    2009-01-01

    Cytoskeletal reorganization is an ongoing process when cells adhere, move or invade extracellular substrates. The cellular force generation and transmission are determined by the intactness of the actomyosin-(focal adhesion complex)-integrin connection. We investigated the intracellular course of action in mouse embryonic fibroblasts deficient in the focal adhesion proteins vinculin and focal adhesion kinase (FAK) and the nuclear matrix protein p53 using magnetic tweezer and nanoparticle tracking techniques. Results show that the lack of these proteins decrease cellular stiffness and affect cell rheological behavior. The decrease in cellular binding strength was higher in FAK- to vinculin-deficient cells, whilst p53-deficient cells showed no effect compared to wildtype cells. The intracellular cytoskeletal activity was lowest in wildtype cells, but increased in the following order when cells lacked FAK+p53 > p53 > vinculin. In summary, cell mechanical processes are differently affected by the focal adhesion proteins vinculin and FAK than by the nuclear matrix protein, p53.

  3. Focal Mechanism of Semi-Volcanic Deep Low-Frequency Earthquakes in Eastern Shimane

    Science.gov (United States)

    Aso, N.; Ohta, K.; Ide, S.

    2012-12-01

    Many deep low-frequency earthquakes (LFEs) occur near the island arc Mohorovicic discontinuities and far from both active volcanoes and plate boundaries. They are quite similar to volcanic LFEs beneath active volcanoes, which infers some fluid movement in the source region, and we regard them as "semi-volcanic" LFEs [Aso et al., 2011; 2012 (submitted)]. Several previous studies determined the focal mechanisms of volcanic and semi-volcanic LFEs using a small portion of information of the waveforms. Although the estimated focal mechanisms are various, they may not necessary support the variety of the actual physical process, owing to the large determination error [e.g., Nishidomi and Takeo, 1996; Ohmi and Obara, 2002; Nakamichi et al., 2003]. Here we determine the focal mechanisms by waveform inversion for LFEs in eastern Shimane in western Japan, where many LFEs occurred in a quiet region. The locations are also close to the fault plane of the 2000 western Tottori earthquake of Mw6.6, and right beneath Yokota volcano, which is a Quaternary volcanic cluster. We estimated the focal mechanisms of semi-volcanic LFEs in eastern Shimane by moment tensor inversion. The data are velocity seismograms at five stations of Hi-net near the epicenters. For each seismogram, we extracted a 1.5-second time window beginning from 0.2 seconds before the arrivals of either P-wave in a vertical component or S-wave in a horizontal component. The arrival time of each phase is picked manually first, and then corrected to minimize the variance between observed and synthetic waveforms. The local site amplification is estimated using far-field body waves from deep intraslab earthquakes, and collected for each seismogram. The synthetic waveforms were calculated using the discrete wavenumber integration method developed by Takeo [1985] for a horizontally layered structure. For 38 LFEs, which are equal to or larger than M1.2 (JMA magnitude) and recorded at all five stations, the focal mechanisms

  4. Sensitivity of stress inversion of focal mechanisms to pore pressure changes

    Czech Academy of Sciences Publication Activity Database

    Martínez-Garzón, P.; Vavryčuk, Václav; Kwiatek, G.; Bohnhoff, M.

    2016-01-01

    Roč. 43, č. 16 (2016), s. 8441-8450 ISSN 0094-8276 R&D Projects: GA ČR(CZ) GAP210/12/1491; GA ČR(CZ) GC16-19751J Institutional support: RVO:67985530 Keywords : fault ing regime * fluid-induced seismicity * focal mechanisms Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 4.253, year: 2016

  5. Joint Source Location and Focal Mechanism Inversion: efficiency, accuracy and applications

    Science.gov (United States)

    Liang, C.; Yu, Y.

    2017-12-01

    The analysis of induced seismicity has become a common practice to evaluate the results of hydraulic fracturing treatment. Liang et al (2016) proposed a joint Source Scanning Algorithms (jSSA for short) to obtain microseismic events and focal mechanisms simultaneously. The jSSA is superior over traditional SSA in many aspects, but the computation cost is too significant to be applied in real time monitoring. In this study, we have developed several scanning schemas to reduce computation time. A multi-stage scanning schema is proved to be able to improve the efficiency significantly while also retain its accuracy. A series of tests have been carried out by using both real field data and synthetic data to evaluate the accuracy of the method and its dependence on noise level, source depths, focal mechanisms and other factors. The surface-based arrays have better constraints on horizontal location errors (0.5). For sources with varying rakes, dips, strikes and depths, the errors are mostly controlled by the partition of positive and negative polarities in different quadrants. More evenly partitioned polarities in different quadrants yield better results in both locations and focal mechanisms. Nevertheless, even with bad resolutions for some FMs, the optimized jSSA method can still improve location accuracies significantly. Based on much more densely distributed events and focal mechanisms, a gridded stress inversion is conducted to get a evenly distributed stress field. The full potential of the jSSA has yet to be explored in different directions, especially in earthquake seismology as seismic array becoming incleasingly dense.

  6. Influencia de un bloque rígido en un sistema de fallas de rumbo: modelamiento análogo Influence of a rigid block in a strike-slip fault system: analogue modelling

    Directory of Open Access Journals (Sweden)

    Thierry Nalpas

    2011-01-01

    Full Text Available En este trabajo se presenta un estudio de modelamiento análogo sobre la naturaleza, geometría y cinemática de la deformación a lo largo de fallas de rumbo dada la presencia de un bloque rígido en su trayectoria de deformación. Los modelos análogos están apropiadamente escalados considerando las características reológicas de los materiales que se desean contrastar en la deformación. Dos grandes parámetros fueron probados: la configuración del bloque rígido, variando su forma y tamaño, y el monto del desplazamiento. Los resultados experimentales muestran el desarrollo de rotaciones, fallas y pliegues como producto de la presencia de un bloque rígido en la trayectoria de falla. Los diversos casos geométricos probados pueden ser empleados para su comparación con sistemas de fallas de rumbo en los cuales existen diferencias litológicas de comportamiento reológico diferencial, como por ejemplo el caso del 'Núcleo rígido de Limón Verde' al sur de Chuquicamata, ubicado en la trayectoria del sistema de fallas de Domeyko.This work addresses the kinematic effects of a rigid block in strike-slip systems by using analogue models. The experiments (size, behaviour of materials were scaled down in order to represent deformation of the tested rheologic contrast conditions in deformation. Two main parameters were tested: the configuration of the rigid block, changing its form and size, and the amount of displacement. The experiments evidenced the development of rotations, faults and folds along the fault trajectory, as resulting from the presence of the rigid block during the deformation. Testing of diverse geometric situations may be used for comparison to strike-slip fault systems in which different lithologies and rheologic behaviour exist, for example, presence of the 'Limón Verde rigid core' along the Domeyko fault system, just south of Chuquicamata.

  7. The role of focal adhesion kinase in the regulation of cellular mechanical properties

    International Nuclear Information System (INIS)

    Mierke, Claudia Tanja

    2013-01-01

    The regulation of mechanical properties is necessary for cell invasion into connective tissue or intra- and extravasation through the endothelium of blood or lymph vessels. Cell invasion is important for the regulation of many healthy processes such as immune response reactions and wound healing. In addition, cell invasion plays a role in disease-related processes such as tumor metastasis and autoimmune responses. Until now the role of focal adhesion kinase (FAK) in regulating mechanical properties of cells and its impact on cell invasion efficiency is still not well known. Thus, this review focuses on mechanical properties regulated by FAK in comparison to the mechano-regulating protein vinculin. Moreover, it points out the connection between cancer cell invasion and metastasis and FAK by showing that FAK regulates cellular mechanical properties required for cellular motility. Furthermore, it sheds light on the indirect interaction of FAK with vinculin by binding to paxillin, which then impairs the binding of paxillin to vinculin. In addition, this review emphasizes whether FAK fulfills regulatory functions similar to vinculin. In particular, it discusses the differences and the similarities between FAK and vinculin in regulating the biomechanical properties of cells. Finally, this paper highlights that both focal adhesion proteins, vinculin and FAK, synergize their functions to regulate the mechanical properties of cells such as stiffness and contractile forces. Subsequently, these mechanical properties determine cellular invasiveness into tissues and provide a source sink for future drug developments to inhibit excessive cell invasion and hence, metastases formation. (paper)

  8. The role of focal adhesion kinase in the regulation of cellular mechanical properties

    Science.gov (United States)

    Mierke, Claudia Tanja

    2013-12-01

    The regulation of mechanical properties is necessary for cell invasion into connective tissue or intra- and extravasation through the endothelium of blood or lymph vessels. Cell invasion is important for the regulation of many healthy processes such as immune response reactions and wound healing. In addition, cell invasion plays a role in disease-related processes such as tumor metastasis and autoimmune responses. Until now the role of focal adhesion kinase (FAK) in regulating mechanical properties of cells and its impact on cell invasion efficiency is still not well known. Thus, this review focuses on mechanical properties regulated by FAK in comparison to the mechano-regulating protein vinculin. Moreover, it points out the connection between cancer cell invasion and metastasis and FAK by showing that FAK regulates cellular mechanical properties required for cellular motility. Furthermore, it sheds light on the indirect interaction of FAK with vinculin by binding to paxillin, which then impairs the binding of paxillin to vinculin. In addition, this review emphasizes whether FAK fulfills regulatory functions similar to vinculin. In particular, it discusses the differences and the similarities between FAK and vinculin in regulating the biomechanical properties of cells. Finally, this paper highlights that both focal adhesion proteins, vinculin and FAK, synergize their functions to regulate the mechanical properties of cells such as stiffness and contractile forces. Subsequently, these mechanical properties determine cellular invasiveness into tissues and provide a source sink for future drug developments to inhibit excessive cell invasion and hence, metastases formation.

  9. Towards routine determination of focal mechanisms obtained from first motion P-wave arrivals

    Science.gov (United States)

    Lentas, K.

    2018-03-01

    The Bulletin of the International Seismological Centre (ISC) contains information on earthquake mechanisms collected from many different sources including national and global agencies, resulting in a satisfactory coverage over a wide magnitude range (M ˜2-9). Nevertheless, there are still a vast number of earthquakes with no reported source mechanisms especially for magnitudes up to 5. This study investigates the possibility of calculating earthquake focal mechanisms in a routine and systematic way based on P-wave first motion polarities. Any available parametric data in the ISC database is being used, as well as auto-picked polarities from waveform data up to teleseismic epicentral distances (90°) for stations that are not reported to the ISC. The determination of the earthquake mechanisms is carried out with a modified version of the HASH algorithm that is compatible with a wide range of epicentral distances and takes into account the ellipsoids defined by the ISC location errors, and the Earth's structure uncertainties. Initially, benchmark tests for a set of ISC reviewed earthquakes (mb > 4.5) are carried out and the HASH mechanism classification scheme is used to define the mechanism quality. Focal mechanisms of quality A, B and C with an azimuthal gap up to 90° compare well to the benchmark mechanisms. Nevertheless, the majority of the obtained mechanisms fall into class D as a result of limited polarity data from stations in local/regional epicentral distances. Specifically, the computation of the minimum rotation angle between the obtained mechanisms and the benchmarks, reveals that 41 per cent of the examined earthquakes show rotation angles up to 35°. Finally, the current technique is applied to a small set of earthquakes from the reviewed ISC bulletin where 62 earthquakes, with no previously reported source mechanisms, are successfully obtained.

  10. Earthquake source parameter and focal mechanism estimates for the Western Quebec Seismic Zone in eastern Canada

    Science.gov (United States)

    Rodriguez Padilla, A. M.; Onwuemeka, J.; Liu, Y.; Harrington, R. M.

    2017-12-01

    The Western Quebec Seismic Zone (WQSZ) is a 160-km-wide band of intraplate seismicity extending 500 km from the Adirondack Highlands (United States) to the Laurentian uplands (Canada). Historically, the WQSZ has experienced over fifteen earthquakes above magnitude 5, with the noteworthy MN5.2 Ladysmith event on May 17, 2013. Previous studies have associated seismicity in the area to the reactivation of Early Paleozoic normal faults within a failed Iapetan rift arm, or strength contrasts between mafic intrusions and felsic rocks due to the Mesozoic track of the Great Meteor hotspot. A good understanding of seismicity and its relation to pre-existing structures requires information about event source properties, such as static stress drop and fault plane orientation, which can be constrained via spectral analysis and focal mechanism solutions. Using data recorded by the CNSN and USArray Transportable Array, we first characterize b-value for 709 events between 2012 and 2016 in WQSZ, obtaining a value of 0.75. We then determine corner frequency and seismic moment values by fitting S-wave spectra on transverse components at all stations for 35 events MN 2.7+. We select event pairs with highly similar waveforms, proximal hypocenters, and magnitudes differing by 1-2 units. Our preliminary results using single-station spectra show corner frequencies of 15 to 40 Hz and stress drop values between 7 and 130 MPa, typical of intraplate seismicity. Last, we solve focal mechanism solutions of 35 events with impulsive P-wave arrivals at a minimum of 8 stations using the hybridMT moment tensor inversion algorithm. Our preliminary results suggest predominantly thrust faulting mechanisms, and at times oblique thrust faulting. The P-axis trend of the focal mechanism solutions suggests a principal stress orientation of NE-SW, which is consistent with that derived from focal mechanisms of earthquakes prior to 2013. We plan to fit the event pair spectral ratios to correct for attenuation

  11. Determination Hypocentre and Focal Mechanism Earthquake of Oct 31, 2016 in Bone, South Sulawesi

    Science.gov (United States)

    Altin Massinai, Muhammad; Fawzy Ismullah M, Muhammad

    2018-03-01

    Indonesian Meteorology, Climatology and Geophysics Agency (BMKG) recorded an earthquake with M4.6 on at October 31, 2016 at Bone District, around 80 Km northeast form Makassar, South Sulawesi. The earthquake occurred 18:18:14 local time in 4.7°S, 120°E with depth 10 Km. Seismicity around location predicted caused by activity Walennae fault. We reprocessed earthquake data to determine precise hypocentre location and focal mechanism. The P- and S-wave arrival time got from BMKG used as input HYPOELLIPSE code to determine hypocentre. The results showed that the earthquake occurred 10:18:14.46 UTC in 4.638°S, 119.966°E with depth 24.76 Km. The hypocentre resolved 10 Km fix depth and had lower travel time residual than BMKG result. Focal mechanism determination used Azmtak code based on the first arrival polarity at earthquake waveform manually picked. The result showed a reverse mechanism with strike direction 38°, dip 44°, rake angle 134° on fault plane I and strike direction 164°, dip 60°, rake angle 56° on fault plane II. So, the earthquake which may be related to a reverse East Walennae Fault.

  12. Significado tectónico y migración de fluidos hidrotermales en una red de fallas y vetas de un Dúplex de rumbo: un ejemplo del Sistema de Falla de Atacama Tectonic significance and hydrothermal fluid migration within a strike-slip duplex fault-vein network: an example from the Atacama Fault System

    Directory of Open Access Journals (Sweden)

    Viviana Olivares

    2010-07-01

    (extension veins and oblique-extension veins, whereas others show mineral fibers that are parallel to striae of the hosting faults (fault-veins. The latter show kinematic indicators that are compatible with those of the faults, suggesting they were synkinematic with strike-slip duplex development. The vein microstructure suggests that they form from fluid-filled open fractures under subhydrosthatic pressures suggesting that mineral precipitation was triggered by pressure drops at shallow crustal levels (<4 km consistent with the suction pump mechanism. 40Ar/39Ar and K-Ar ages between 119 and 141 Ma are interpreted as the approximate time window within which the duplex and veins were developed.

  13. Irregular focal mechanisms observed at Salton Sea Geothermal Field: Possible influences of anthropogenic stress perturbations

    Science.gov (United States)

    Crandall-Bear, Aren; Barbour, Andrew J.; Schoenball, Martin; Schoenball, Martin

    2018-01-01

    At the Salton Sea Geothermal Field (SSGF), strain accumulation is released through seismic slip and aseismic deformation. Earthquake activity at the SSGF often occurs in swarm-like clusters, some with clear migration patterns. We have identified an earthquake sequence composed entirely of focal mechanisms representing an ambiguous style of faulting, where strikes are similar but deformation occurs due to steeply-dipping normal faults with varied stress states. In order to more accurately determine the style of faulting for these events, we revisit the original waveforms and refine estimates of P and S wave arrival times and displacement amplitudes. We calculate the acceptable focal plane solutions using P-wave polarities and S/P amplitude ratios, and determine the preferred fault plane. Without constraints on local variations in stress, found by inverting the full earthquake catalog, it is difficult to explain the occurrence of such events using standard fault-mechanics and friction. Comparing these variations with the expected poroelastic effects from local production and injection of geothermal fluids suggests that anthropogenic activity could affect the style of faulting.

  14. Stress fields in the Antarctic plate inferred from focal mechanisms of intraplate earthquakes

    Directory of Open Access Journals (Sweden)

    Atsuki Kubo

    1999-03-01

    Full Text Available Typical directional features of intraplate stresses are extracted from focal mechanism solutions of earthquakes in the Antarctic plate. Typical directions of stresses are obtained in the following regions, 1 Bellingshausen Sea, 2 south of Juan-Fernandez microplate, 3 Balleny Island region and 4 Kerguelen region. P axes in regions 1 and 2 have been interpreted by ridge push force. However these interpretations are based on one focal mechanism for each event and on crude physical concept of ridge push. It is difficult to explain intraplate stress fields in these regions only by the local ridge push force. The stress direction in region 3 can be interpreted by both deformation near triple junction and deformation due to deglaciation. Earthquakes near region 4 appear to be normal fault event. Because normal fault events appear only in the younger ocean floor, the stress field may be affected by thermal features such as hot spots Quantitative modeling and superposition of various stress factors are required to discriminate among stress origins. It is difficult to discuss stress directions in and around Antarctic continent, because number of the earthquakes is not enough.

  15. The Scenic performance mechanism in the Aristophanes' comedies: the prompter and the focalization

    Directory of Open Access Journals (Sweden)

    Jane Kelly de Oliveira

    2017-07-01

    Full Text Available In this article, we aimed to point two important mechanisms of scenic performance in the plays of the Greek comedy writer Aristophanes (V BC. Our start assumption is that it is possible to find in the text important marks for the scenic operationalization of those comedies. In the time when those comedies were composed, the author knew the material conditions of scenic performance and he used some interesting strategies, and we highlight two of them: (i he inserted reminder-speech inside the sing of chorus to work as a prompter for the coreutas' choreography; (ii he used the chorus' collective body to indicate to the spectator which scenic elements deserve the attention for being important for the progress of the plot. These two play composition strategies are similar, but not equal, to the contemporary concepts of prompter and focalization.

  16. Analytical magmatic source modelling from a joint inversion of ground deformation and focal mechanisms data

    Science.gov (United States)

    Cannavo', Flavio; Scandura, Danila; Palano, Mimmo; Musumeci, Carla

    2014-05-01

    Seismicity and ground deformation represent the principal geophysical methods for volcano monitoring and provide important constraints on subsurface magma movements. The occurrence of migrating seismic swarms, as observed at several volcanoes worldwide, are commonly associated with dike intrusions. In addition, on active volcanoes, (de)pressurization and/or intrusion of magmatic bodies stress and deform the surrounding crustal rocks, often causing earthquakes randomly distributed in time within a volume extending about 5-10 km from the wall of the magmatic bodies. Despite advances in space-based, geodetic and seismic networks have significantly improved volcano monitoring in the last decades on an increasing worldwide number of volcanoes, quantitative models relating deformation and seismicity are not common. The observation of several episodes of volcanic unrest throughout the world, where the movement of magma through the shallow crust was able to produce local rotation of the ambient stress field, introduces an opportunity to improve the estimate of the parameters of a deformation source. In particular, during these episodes of volcanic unrest a radial pattern of P-axes of the focal mechanism solutions, similar to that of ground deformation, has been observed. Therefore, taking into account additional information from focal mechanisms data, we propose a novel approach to volcanic source modeling based on the joint inversion of deformation and focal plane solutions assuming that both observations are due to the same source. The methodology is first verified against a synthetic dataset of surface deformation and strain within the medium, and then applied to real data from an unrest episode occurred before the May 13th 2008 eruption at Mt. Etna (Italy). The main results clearly indicate as the joint inversion improves the accuracy of the estimated source parameters of about 70%. The statistical tests indicate that the source depth is the parameter with the highest

  17. Microseismic Event Relocation and Focal Mechanism Estimation Based on PageRank Linkage

    Science.gov (United States)

    Aguiar, A. C.; Myers, S. C.

    2017-12-01

    Microseismicity associated with enhanced geothermal systems (EGS) is key in understanding how subsurface stimulation can modify stress, fracture rock, and increase permeability. Large numbers of microseismic events are commonly associated with hydroshearing an EGS, making data mining methods useful in their analysis. We focus on PageRank, originally developed as Google's search engine, and subsequently adapted for use in seismology to detect low-frequency earthquakes by linking events directly and indirectly through cross-correlation (Aguiar and Beroza, 2014). We expand on this application by using PageRank to define signal-correlation topology for micro-earthquakes from the Newberry Volcano EGS in Central Oregon, which has been stimulated two times using high-pressure fluid injection. We create PageRank signal families from both data sets and compare these to the spatial and temporal proximity of associated earthquakes. PageRank families are relocated using differential travel times measured by waveform cross-correlation (CC) and the Bayesloc approach (Myers et al., 2007). Prior to relocation events are loosely clustered with events at a distance from the cluster. After relocation, event families are found to be tightly clustered. Indirect linkage of signals using PageRank is a reliable way to increase the number of events confidently determined to be similar, suggesting an efficient and effective grouping of earthquakes with similar physical characteristics (ie. location, focal mechanism, stress drop). We further explore the possibility of using PageRank families to identify events with similar relative phase polarities and estimate focal mechanisms following Shelly et al. (2016) method, where CC measurements are used to determine individual polarities within event clusters. Given a positive result, PageRank might be a useful tool in adaptive approaches to enhance production at well-instrumented geothermal sites. Prepared by LLNL under Contract DE-AC52-07NA27344

  18. Faulting mechanisms and stress regime at the European HDR site of Soultz-sous-Forets, France

    International Nuclear Information System (INIS)

    Cuenot, Nicolas; Charlety, Jean; Haessler, Henri; Dorbath, Louis

    2006-01-01

    The state of stress and its implications for shear on fault planes during fluid injection are crucial issues for the HDR (Hot Dry Rock) or EGS (Enhanced or Engineered Geothermal System) concept. This is especially true for hydraulic stimulation experiments, aimed at enhancing the connectivity of a borehole to the natural fracture network, since they tend to induce the shearing of fractures, which is controlled by the local stress regime. During the 2000 and 2003 stimulation tests at Soultz-sous-Forets, France, about 10,000 microearthquakes were located with a surface seismological network. Hundreds of double-couple (DC) focal mechanisms were automatically determined from first-motion polarities using the FPFIT program [Reasenberg, P.A., Oppenheimer, D., 1985. FPFIT, FPPLOT and FPPAGE: Fortran computer programs for calculating and displaying earthquake fault-plane solutions. US Geological Survey Open-File Report 85-739, 25 pp.]. The majority of these mechanisms indicate normal-faulting movement with a more or less pronounced strike-slip component. Some quasi-pure strike-slip events also occurred, especially in the deeper part of the stimulated rock volume, at more than 5 km depth. Although we found a double-couple solution for all events, we tried to observe and quantify the proportion of the non-double-couple (NDC) component in the seismic moment tensor for several microseisms from the 2003 data. The study shows that the NDC is higher for the events in the vicinity of the injection well than for the events far from the well. We used the method of Rivera and Cisternas [Rivera, L., Cisternas, A., 1990. Stress tensor and fault-plane solutions for a population of earthquakes. Bull. Seismol. Soc. Am. 80, 600-614.] to perform the inversion of the deviatoric part of the stress tensor from P-wave polarities. This method was applied to different datasets from the 2000 test, taken from the shallower and deeper parts of the stimulated region. The results show a stable

  19. Faulting mechanisms and stress regime at the European HDR site of Soultz-sous-Forets, France

    Energy Technology Data Exchange (ETDEWEB)

    Cuenot, Nicolas; Charlety, Jean; Haessler, Henri [Institut de Physique du Globe de Strasbourg, Ecole et Observatoire des Sciences de la Terre (IPGS-EOST), 5 rue Rene Descartes, 67084 Strasbourg Cedex (France); Dorbath, Louis [Institut de Physique du Globe de Strasbourg, Ecole et Observatoire des Sciences de la Terre (IPGS-EOST), 5 rue Rene Descartes, 67084 Strasbourg Cedex (France); Institut de Recherche pour le Developpement, Laboratoire des Mecanismes et Transferts en Geologie (IRD, LMTG), 14 Avenue Edouard Belin, 31400 Toulouse (France)

    2006-10-15

    The state of stress and its implications for shear on fault planes during fluid injection are crucial issues for the HDR (Hot Dry Rock) or EGS (Enhanced or Engineered Geothermal System) concept. This is especially true for hydraulic stimulation experiments, aimed at enhancing the connectivity of a borehole to the natural fracture network, since they tend to induce the shearing of fractures, which is controlled by the local stress regime. During the 2000 and 2003 stimulation tests at Soultz-sous-Forets, France, about 10,000 microearthquakes were located with a surface seismological network. Hundreds of double-couple (DC) focal mechanisms were automatically determined from first-motion polarities using the FPFIT program [Reasenberg, P.A., Oppenheimer, D., 1985. FPFIT, FPPLOT and FPPAGE: Fortran computer programs for calculating and displaying earthquake fault-plane solutions. US Geological Survey Open-File Report 85-739, 25 pp.]. The majority of these mechanisms indicate normal-faulting movement with a more or less pronounced strike-slip component. Some quasi-pure strike-slip events also occurred, especially in the deeper part of the stimulated rock volume, at more than 5 km depth. Although we found a double-couple solution for all events, we tried to observe and quantify the proportion of the non-double-couple (NDC) component in the seismic moment tensor for several microseisms from the 2003 data. The study shows that the NDC is higher for the events in the vicinity of the injection well than for the events far from the well. We used the method of Rivera and Cisternas [Rivera, L., Cisternas, A., 1990. Stress tensor and fault-plane solutions for a population of earthquakes. Bull. Seismol. Soc. Am. 80, 600-614.] to perform the inversion of the deviatoric part of the stress tensor from P-wave polarities. This method was applied to different datasets from the 2000 test, taken from the shallower and deeper parts of the stimulated region. The results show a stable

  20. Analogue modelling of strike-slip fault propagation across a rheological/morphological crustal anisotropy: implications for the morphotectonic evolution of the Gloria Fault - Tore Madeira Rise area in NE Atlantic.

    Science.gov (United States)

    Tomás, Ricardo; Rosas, Filipe M.; Duarte, João C.; Terrinha, Pedro; Kullberg, Maria C.; Almeida, Jaime; Barata, Frederico; Carvalho, Bruno; Almeida, Pedro

    2015-04-01

    The Gloria Fault (GF) marks the E-W dextral transcurrent plate boundary between Eurasia and Africa in NE Atlantic, displaying complying high magnitude (historical and instrumental) seismic activity (e.g. M=7.1 in 1939 and M=8.4 in 1941, Bufforn et al., 1988), and cutting across a NNE-SSW 1000 km long bathymetric ridge: the so called Tore-Madeira Rise - TMR (rising in average 3km above the abyssal plain). The precise origin and tectono-magmatic evolution of the TMR is still not fully understood, although reported wide-angle refraction data points to a rheological configuration comprising an isostatically compensated thickened oceanic crust, possibly formed during a period of high accretion in the Mid-Atlantic Ridge (Pierce and Barton, 1991). Widespread evidence for volcanic activity has also been recognized, spanning from late Cretaceous to Present (Geldmacher et al. 2006, Merle et al. 2009), noticeably with the most recent volcanism (~500 Ky) occurring as tectonically aligned volcanic plugs, distributed along the E-W tectonic trend of the GF-related structures. To better understand the complex interference at play in this key area between the tectonic structures (essentially determined by the Gloria Fault system), the present and past magmatic activity and the resulting seafloor morphology, a series of dynamically scaled analogue modelling experiments have been conceived and carried out. The main focus of this experimental work was to decipher the potential influence of a rheological vs. morphological anisotropy (accounting for the TMR) on the lateral propagation of a major right-lateral strike-slip fault (representing the GF). The preliminary comparison of the obtained experimental results with the natural morphotectonic pattern in the study area reveals, not only a strong tectonic control of the ongoing volcanism, manifested by the observed preferred directions of aligned volcanic plugs, but also a so far unsuspected deflection/distributed pattern of several

  1. Constraints on the rheology of the lower crust in a strike-slip plate boundary: evidence from the San Quintín xenoliths, Baja California, Mexico

    Directory of Open Access Journals (Sweden)

    T. van der Werf

    2017-12-01

    Full Text Available The rheology of lower crust and its transient behavior in active strike-slip plate boundaries remain poorly understood. To address this issue, we analyzed a suite of granulite and lherzolite xenoliths from the upper Pleistocene–Holocene San Quintín volcanic field of northern Baja California, Mexico. The San Quintín volcanic field is located 20 km east of the Baja California shear zone, which accommodates the relative movement between the Pacific plate and Baja California microplate. The development of a strong foliation in both the mafic granulites and lherzolites, suggests that a lithospheric-scale shear zone exists beneath the San Quintín volcanic field. Combining microstructural observations, geothermometry, and phase equilibria modeling, we estimated that crystal-plastic deformation took place at temperatures of 750–890 °C and pressures of 400–560 MPa, corresponding to 15–22 km depth. A hot crustal geotherm of 40 ° C km−1 is required to explain the estimated deformation conditions. Infrared spectroscopy shows that plagioclase in the mafic granulites is relatively dry. Microstructures are interpreted to show that deformation in both the uppermost lower crust and upper mantle was accommodated by a combination of dislocation creep and grain-size-sensitive creep. Recrystallized grain size paleopiezometry yields low differential stresses of 12–33 and 17 MPa for plagioclase and olivine, respectively. The lower range of stresses (12–17 MPa in the mafic granulite and lherzolite xenoliths is interpreted to be associated with transient deformation under decreasing stress conditions, following an event of stress increase. Using flow laws for dry plagioclase, we estimated a low viscosity of 1.1–1.3×1020 Pa ⋅ s for the high temperature conditions (890 °C in the lower crust. Significantly lower viscosities in the range of 1016–1019 Pa ⋅ s, were estimated using flow laws for wet plagioclase. The

  2. Determinations of directions of the mean stress field in Sichuan-Yunnan region from a number of focal mechanism solutions

    Science.gov (United States)

    Zhong, Ji-Mao; Cheng, Wan-Zheng

    2006-07-01

    Based on the spatial orientation and slip direction of the fault plane solutions, we present the expression of corresponding mechanical axis tensor in geographic coordinate system, and then put forward a method for calculating average mechanical axis tensor and its eigenvalues, which involves solving the corresponding eigenequation. The method for deducing mean stress field from T, B, and P axes parameters of a number of focal mechanism solutions has been verified by inverting data of mean stress fields in Fuyun region and in Tangshan region with fitting method of slip direction, and both results are consistent. To study regional average stress field, we need to choose a population of focal mechanism solutions of earthquakes in the massifs where there are significant tectonic structures. According to the focal mechanism solutions of 256 moderate-strong earthquakes occurred in 13 seismic zones of Sichuan-Yunnan region, the quantitative analysis results of stress tensor in each seismic zone have been given. The algorithm of such method is simple and convenient, which makes the method for analyzing tectonic stress field with large amount of focal mechanism solution data become quantified.

  3. Transcurrencia a lo largo de la Falla Sierra de Varas (Sistema de fallas de la Cordillera de Domeyko, norte de Chile Strike-slip along the Sierra de Varas Fault (Cordillera de Domeyko Fault-System, northern Chile

    Directory of Open Access Journals (Sweden)

    Hans Niemeyer

    2009-01-01

    Aguada del Hornito-Aguada del Cerro Alto de Varas segment. Upper Paleozoic granitoids of the same composition, internal structure and age were cut and displaced by the fault. A sinistral horizontal separation of 15.6±1 kmwitha vertical componentof 4.9±0.1 km, suggests a sinistral-reverse net displacement of 16.4±1 km. Thisis consistent with the local stratigraphic section that was eroded from the eastern block. A kinematic and dynamic analysis of mesofaults spatially related to the SVF displacements was conducted to identify the different fault populations and to obtain the stress tensor. Two structural systems were identified: an early reverse-strike-slip system and a late dextral superposed system. The first one ocurred during late middle Eocene, and the second is post-Miocene with an horizontal displacement of 0.6 km. The presence of coeval strike-slip displacements along the Sierra de Varas Fault and reverse displacements in a 'reverse flower' in the studied segment show that the structural evolution of the Sierra de Varas was dominated by a bulk transpression during the late middle Eocene. The left-lateral displacement here demonstrated for the Sierra de Varas Fault and its inflection to the SE, south of the Aguada del Cerro Alto de Varas are compatible with the westward vergence of the folds and reverse faults in the El Profeta fault-and-thrust belt, which should be also the result of the transpression.

  4. Quantifying capability of a local seismic network in terms of locations and focal mechanism solutions of weak earthquakes

    Czech Academy of Sciences Publication Activity Database

    Fojtíková, Lucia; Kristeková, M.; Málek, Jiří; Sokos, E.; Csicsay, K.; Zahradník, J.

    2016-01-01

    Roč. 20, č. 1 (2016), 93-106 ISSN 1383-4649 R&D Projects: GA ČR GAP210/12/2336 Institutional support: RVO:67985891 Keywords : Focal-mechanism uncertainty * Little Carpathians * Relative location uncertainty * Seismic network * Uncertainty mapping * Waveform inversion * Weak earthquake s Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 1.089, year: 2016

  5. Contemporary Crustal Deformation Within the Pamir Plateau Constrained by Geodetic Observations and Focal Mechanism Solutions

    Science.gov (United States)

    Pan, Zhengyang; He, Jiankun; Li, Jun

    2018-04-01

    We used an updated data set of 192 GPS-derived surface velocities and 393 earthquake focal mechanisms (Mw > 3.0, hypocenter depths https://doi.org/10.1029/2005jb004144, 2006). The results show that the crustal stress field around the Pamir Plateau is predominantly characterized by NNW-SSE compression and E-W extension, which is consistent with the principal orientations of the two-dimensional surface strain rate tensor. This agreement supports the notion that the Pamir and southwestern Tien Shan are uniformly strained blocks. In particular, the fan-shaped rotational pattern between {Shmax} and the strain rate from the western Pamir to the Tajik Basin shows that the counterclockwise rotation of the {Shmax} orientation is associated with vertical deformation, which is consistent with the idea of Schurr et al. (Tectonics 33(8):2014TC003576, 2014) concerning the gravitational collapse and westward extrusion of the crust in the western Pamir. We propose that such a stress-strain pattern, dominated by NNW-ESE oriented compression and E-W trending extension, originated from a combination of the northward push of the Indian continent and the southward subduction of the Tien Shan.

  6. Robust automated classification of first-motion polarities for focal mechanism determination with machine learning

    Science.gov (United States)

    Ross, Z. E.; Meier, M. A.; Hauksson, E.

    2017-12-01

    Accurate first-motion polarities are essential for determining earthquake focal mechanisms, but are difficult to measure automatically because of picking errors and signal to noise issues. Here we develop an algorithm for reliable automated classification of first-motion polarities using machine learning algorithms. A classifier is designed to identify whether the first-motion polarity is up, down, or undefined by examining the waveform data directly. We first improve the accuracy of automatic P-wave onset picks by maximizing a weighted signal/noise ratio for a suite of candidate picks around the automatic pick. We then use the waveform amplitudes before and after the optimized pick as features for the classification. We demonstrate the method's potential by training and testing the classifier on tens of thousands of hand-made first-motion picks by the Southern California Seismic Network. The classifier assigned the same polarity as chosen by an analyst in more than 94% of the records. We show that the method is generalizable to a variety of learning algorithms, including neural networks and random forest classifiers. The method is suitable for automated processing of large seismic waveform datasets, and can potentially be used in real-time applications, e.g. for improving the source characterizations of earthquake early warning algorithms.

  7. High-Precision Locations and the Stress Field from Instrumental Seismicity, Moment Tensors, and Short-Period Mechanisms through the Mina Deflection, Central Walker Lane

    Science.gov (United States)

    Ruhl, C. J.; Smith, K. D.

    2012-12-01

    The Mina Deflection (MD) region of the central Walker Lane of eastern California and western Nevada, is a complex zone of northeast-trending normal, and primarily left-lateral strike-slip to oblique-slip faulting that separates the Southern Walker Lane (SWL) from a series of east-tilted normal fault blocks in the Central Walker Lane (CWL) (Faulds and Henry, 2008; Surpless, 2008). The MD accommodates the transfer of right-lateral strike-slip motion from northwest-striking faults in the SWL to a series of left-stepping northwest-striking right-lateral strike-slip faults in the CWL, east of the Wassuk Range near Hawthorne, NV. The ~50 km wide ~80 km long right-step is a distinct transition in regional physiography that has been attributed to strain accommodation through pre-Cenozoic lithospheric structures. Several slip transfer mechanisms have been proposed within the MD, from clockwise rotation of high-angle fault blocks (Wesnousky, 2005), to low-angle displacement within the Silver Peak-Lone Mountain complex (Oldow et al., 2001), and curved fault arrays associated with localized basins and tectonic depressions (Ferranti et al., 2009). The region has been a regular source of M4+ events, the most recent being an extended sequence that included twenty-seven M 3.5+ earthquakes (largest event M 4.6) south of Hawthorne in 2011. These earthquakes (Mina, NV, and the 1932 M 7.1 Cedar Mountains earthquake east of the Pilot Mountains. Another persistent feature in the seismicity is an ~40 km long arcuate distribution of activity extending from approximately Queen Valley, north of the White Mountains, to Mono Lake that appears to reflect a southwestern boundary to northeast-striking structures in the MD. Here we develop high-precision relocations of instrumental seismicity in the MD from 1984 through 2012, including relocations of the 2004 sequence, and account for the historical seismic record. MT solutions from published reports and computed from recent M 3.5+ earthquakes as

  8. The impact of static stress change, dynamic stress change, and the background stress on aftershock focal mechanisms

    Science.gov (United States)

    Hardebeck, Jeanne L.

    2014-01-01

    The focal mechanisms of earthquakes in Southern California before and after four M ≥ 6.7 main shocks provide insight into how fault systems respond to stress and changes in stress. The main shock static stress changes have two observed impacts on the seismicity: changing the focal mechanisms in a given location to favor those aligned with the static stress change and changing the spatial distribution of seismicity to favor locations where the static stress change aligns with the background stress. The aftershock focal mechanisms are significantly aligned with the static stress changes for absolute stress changes of ≥ 0.02 MPa, for up to ~20 years following the main shock. The dynamic stress changes have similar, although smaller, effects on the local focal mechanisms and the spatial seismicity distribution. Dynamic stress effects are best observed at long periods (30–60 s) and for metrics based on repeated stress cycling in the same direction. This implies that dynamic triggering operates, at least in part, through cyclic shear stress loading in the direction of fault slip. The background stress also strongly controls both the preshock and aftershock mechanisms. While most aftershock mechanisms are well oriented in the background stress field, 10% of aftershocks are identified as poorly oriented outliers, which may indicate limited heterogeneity in the postmain shock stress field. The fault plane orientations of the outliers are well oriented in the background stress, while their slip directions are not, implying that the background stress restricts the distribution of available fault planes.

  9. Compromising polarity and waveform constraints in focal-mechanism solutions; the Mara Rosa 2010 Mw 4 central Brazil earthquake revisited

    Czech Academy of Sciences Publication Activity Database

    Zahradník, J.; Fojtíková, Lucia; Carvalho, J.; Barros, L.V.; Sokos, E.; Janský, J.

    2015-01-01

    Roč. 63, NOV (2015), s. 323-333 ISSN 0895-9811 R&D Projects: GA ČR GAP210/12/2336 Institutional support: RVO:67985891 Keywords : weak events * focal mechanism * waveforms * polarities * uncertainties * Brazil * Mara Rosa Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 1.737, year: 2015 http://www. science direct.com/ science /article/pii/S0895981115300481

  10. Preliminary seismicity and focal mechanisms for the southern Great Basin of Nevada and California: January 1992 through September 1992

    International Nuclear Information System (INIS)

    Harmsen, S.C.

    1994-01-01

    The telemetered southern Great Basin seismic network (SGBSN) is operated for the Department of Energy's Yucca Mountain Project (YMP). The US Geological Survey, Branch of Earthquake and Landslide Hazards, maintained this network until September 30, 1992, at which time all operational and analysis responsibilities were transferred to the University of Nevada at Reno Seismological Laboratory (UNRSL). This report contains preliminary earthquake and chemical explosion hypocenter listings and preliminary earthquake focal mechanism solutions for USGS/SGBSN data for the period January 1, 1992 through September 30, 1992, 15:00 UTC

  11. Constraints on fault and crustal strength of the Main Ethiopian Rift from formal inversion of earthquake focal mechanism data

    Science.gov (United States)

    Muluneh, Ameha A.; Kidane, Tesfaye; Corti, Giacomo; Keir, Derek

    2018-04-01

    We evaluate the frictional strength of seismogenic faults in the Main Ethiopian Rift (MER) by inverting the available, well-constrained earthquake focal mechanisms. The regional stress field is given by - 119.6°/77.2°, 6.2°/7.6°, and 97.5°/10.2° for trend/plunge of σ1, σ2 and σ3, respectively agrees well with previous fault kinematic and focal mechanism inversions. We determine the coefficient of friction, μ, for 44 seismogenic faults by assuming the pore pressure to be at hydrostatic conditions. Slip on 36 seismogenic faults occurs with μ ≥ 0.4. Slip on the remaining eight faults is possible with low μ. In general, the coefficient of friction in the MER is compatible with a value of μ of 0.59 ± 0.16 (2σ standard deviation). The shear stresses range from 16 to 129 MPa, is similar to crustal shear stress observed in extensional tectonic regimes and global compilations of shear stresses from major fault zones. The maximum shear stress is observed in the ductile crust, below the seismologically determined brittle-ductile transition (BDT) zone. Below the BDT, the crust is assumed to be weak due to thermal modification and/or high pore fluid pressure. Our results indicate linearly increasing μ and shear stress with depth. We argue that in the MER upper crust is strong and deforms according to Coulomb frictional-failure criterion.

  12. Focal degeneration of basal cells and the resultant auto-immunoreactions: a novel mechanism for prostate tumor progression and invasion.

    Science.gov (United States)

    Man, Yan-Gao; Gardner, William A

    2008-01-01

    The development of human prostate cancer is believed to be a multistep process, progressing sequentially from normal, to hyperplasia, to prostatic intraepithelial neoplasia (PIN), and to invasive and metastatic lesions. High grade PIN has been generally considered as the direct precursor of invasive lesions, and the progression of PIN is believed to be triggered primarily, if not solely, by the overproduction of proteolytic enzymes predominately by cancer cells, which result in the degradation of the basement membrane. These theories, however, are hard to reconcile with two main facts: (1) only about 30% untreated PIN progress to invasive stage, while none of the current approaches could accurately identify the specific PIN or individuals at greater risk for progression, and (2) results from recent world-wide clinical trials with a wide variety of proteolytic enzyme inhibitors have been very disappointing, casting doubt on the validity of the proteolytic enzyme theory. Since over 90% of prostate cancer-related deaths result from invasion-related illness and the incidence of PIN could be up to 16.5-25% in routine or ultrasound guided prostate biopsy, there is an urgent need to uncover the intrinsic mechanism of prostate tumor invasion. Promoted by the facts that the basal cell population is the source of several tumor suppressors and the absence of the basal cell layer is the most distinct feature of invasive lesions, our recent studies have intended to identify the early alterations of basal cell layers and their impact on tumor invasion using multidisciplinary approaches. Our studies revealed that a subset of pre-invasive tumors contained focal disruptions (the absence of basal cells resulting in a gap greater than the combined size of at least three epithelial cells) in surrounding basal cell layers. Compared to their non-disrupted counterparts, focally disrupted basal cell layers had several unique features: (1) significantly lower proliferation; (2

  13. Interleukin 1β induces rapid phosphorylation and redistribution of talin: A possible mechanism for modulation of fibroblast focal adhesion

    International Nuclear Information System (INIS)

    Qwarnstroem, E.E.; MacFarlane, S.A.; Page, R.C.; Dower, S.K.

    1991-01-01

    The majority of interleukin 1 (IL-1) receptors in human fibroblasts has been shown to be localized at focal adhesions. This study describes rapid alterations caused by IL-1β/IL-1-receptor interaction at these sites. Fibroblast monolayers, incubated with IL-1β and prepared for electron microscopy, showed successive loss of cell-substratum contact and fewer and less-pronounced processes. Immunocytochemistry revealed loss and redistribution of the talin staining initially observed after 5-15 min of IL-1β incubation. Similarly, the cytoskeleton showed a decrease in staining and a disorganization starting from 15 to 30 min after IL-1 addition, whereas extracellular fibronectin appeared largely unaffected. Prelabeling with [ 32 P]phosphate showed a 2- to 3-fold increase in the level of talin phosphorylation, peaking at 15 min. Phospho amino acid analyses revealed a higher level of serine and threonine phosphorylation. The data suggest that the action of IL-1β on fibroblasts may be partially mediated by direct phosphorylation of talin via activation of a protein serine/threonine kinase, leading to changes in transmembrane linkage proteins and the cytoskeleton. Such alterations at focal adhesions may provide a mechanism by which IL-1 can rapidly modulate cell-matrix interactions during inflammation and wound healing

  14. Focal myositis

    International Nuclear Information System (INIS)

    Kransdorf, M.J.; Temple, H.T.; Sweet, D.E.

    1998-01-01

    Focal myositis is a pseudotumor of soft tissue that typically occurs in the deep soft tissue of the extremities, and is a relatively rare lesion. There is a wide clinical spectrum, with approximately one-third of patients with focal myositis subsequently developing polymyositis, and clinical symptoms of generalized weakness, fever, myalgia, and weight loss, with elevation of creatine phosphokinase. We report the case of a patient with focal myositis who subsequently developed myositis ossificans-like features. (orig.)

  15. Mechanical stimulation of C2C12 cells increases m-calpain expression, focal adhesion plaque protein degradation

    DEFF Research Database (Denmark)

    Grossi, Alberto; Karlsson, Anders H; Lawson, Moira Ann

    2008-01-01

    . Stimulation due to stretch- or load-induced signaling is now beginning to be understood as a factor which affects gene sequences, protein synthesis and an increase in Ca2+ influx in myocytes. Evidence of the involvement of Ca2+ -dependent activity in myoblast fusion, cell membrane and cytoskeleton component...... reorganization due to the activity of the ubiquitous proteolytic enzymes, calpains, has been reported. Whether there is a link between stretch- or load-induced signaling and calpain expression and activation is not known. Using a magnetic bead stimulation assay and C2C12 mouse myoblasts cell population, we have...... demonstrated that mechanical stimulation via laminin receptors leads to an increase in m-calpain expression, but no increase in the expression of other calpain isoforms. Our study revealed that after a short period of stimulation, m-calpain relocates into focal adhesion complexes and is followed by a breakdown...

  16. Quantifying capability of a local seismic network in terms of locations and focal mechanism solutions of weak earthquakes

    Science.gov (United States)

    Fojtíková, Lucia; Kristeková, Miriam; Málek, Jiří; Sokos, Efthimios; Csicsay, Kristián; Zahradník, Jiří

    2016-01-01

    Extension of permanent seismic networks is usually governed by a number of technical, economic, logistic, and other factors. Planned upgrade of the network can be justified by theoretical assessment of the network capability in terms of reliable estimation of the key earthquake parameters (e.g., location and focal mechanisms). It could be useful not only for scientific purposes but also as a concrete proof during the process of acquisition of the funding needed for upgrade and operation of the network. Moreover, the theoretical assessment can also identify the configuration where no improvement can be achieved with additional stations, establishing a tradeoff between the improvement and additional expenses. This paper presents suggestion of a combination of suitable methods and their application to the Little Carpathians local seismic network (Slovakia, Central Europe) monitoring epicentral zone important from the point of seismic hazard. Three configurations of the network are considered: 13 stations existing before 2011, 3 stations already added in 2011, and 7 new planned stations. Theoretical errors of the relative location are estimated by a new method, specifically developed in this paper. The resolvability of focal mechanisms determined by waveform inversion is analyzed by a recent approach based on 6D moment-tensor error ellipsoids. We consider potential seismic events situated anywhere in the studied region, thus enabling "mapping" of the expected errors. Results clearly demonstrate that the network extension remarkably decreases the errors, mainly in the planned 23-station configuration. The already made three-station extension of the network in 2011 allowed for a few real data examples. Free software made available by the authors enables similar application in any other existing or planned networks.

  17. Focal myositis

    International Nuclear Information System (INIS)

    Galloway, H.R.; Dahlstrom, J.E.; Bennett, G.M.

    2001-01-01

    Focal myositis is a rare, benign focal inflammation of muscle. The lesion often presents as a mass that may be mistaken for a soft tissue sarcoma. This report describes the MRI and histopathological features of a case and illustrates how the diagnosis may be suspected on the basis of the MR findings. Copyright (2001) Blackwell Science Pty Ltd

  18. Protective effect of tetraethyl pyrazine against focal cerebral ischemia/reperfusion injury in rats: therapeutic time window and its mechanism.

    Science.gov (United States)

    Jia, Jie; Zhang, Xi; Hu, Yong-Shan; Wu, Yi; Wang, Qing-Zhi; Li, Na-Na; Wu, Cai-Qin; Yu, Hui-Xian; Guo, Qing-Chuan

    2009-03-01

    Tetramethyl pyrazine has been considered an effective agent in treating neurons ischemia/reperfusion injury, but the mechanism of its therapeutic effect remains unclear. This study was to explore the therapeutic time window and mechanism of tetramethyl pyrazine on temporary focal cerebral ischemia/reperfusion injury. Middle cerebral artery occlusion was conducted in male Sprague-Dawley rats and 20 mg/kg of tetramethyl pyrazine was intraperitoneally injected at different time points. At 72 h after reperfusion, all animals' neurologic deficit scores were evaluated. Cerebrums were removed and cerebral infarction volume was measured. The expression of thioredoxin and thioredoxin reductase mRNA was determined at 6 and 24 h after reperfusion. Cerebral infarction volume and neurological deficit scores were significantly decreased in the group with tetramethyl pyrazine treatment. The expression of thioredoxin-1/thioredoxin-2 and thioredoxin reductase-1/thioredoxin reductase-2 was significantly decreased in rats with ischemia/reperfusion injury, while it was increased by tetramethyl pyrazine administration. Treatment with tetramethyl pyrazine, within 4 h after reperfusion, protects the brain from ischemic reperfusion injury in rats. The neuroprotective mechanism of tetramethyl pyrazine treatment is, in part, mediated through the upregulation of thioredoxin transcription.

  19. Improvements of Real Time First Motion Focal Mechanism and Noise Characteristics of New Sites at the Puerto Rico Seismic Network

    Science.gov (United States)

    Williams, D. M.; Lopez, A. M.; Huerfano, V.; Lugo, J.; Cancel, J.

    2011-12-01

    Seismic networks need quick and efficient ways to obtain information related to seismic events for the purposes of seismic activity monitoring, risk assessment, and scientific knowledge among others. As part of an IRIS summer internship program, two projects were performed to provide a tool for quick faulting mechanism and improve seismic data at the Puerto Rico Seismic Network (PRSN). First, a simple routine to obtain a focal mechanisms, the geometry of the fault, based on first motions was developed and implemented for data analysts routine operations at PRSN. The new tool provides the analyst a quick way to assess the probable faulting mechanism that occurred while performing the interactive earthquake location procedure. The focal mechanism is generated on-the-fly when data analysts pick P wave arrivals onsets and motions. Once first motions have been identified, an in-house PRSN utility is employed to obtain the double couple representation and later plotted using GMT's psmeca utility. Second, we addressed the issue of seismic noise related to thermal fluctuations inside seismic vaults. Seismic sites can be extremely noisy due to proximity to cultural activities and unattended thermal fluctuations inside sensor housings, thus resulting in skewed readings. In the past, seismologists have used different insulation techniques to reduce the amount of unwanted noise that a seismometers experience due to these thermal changes with items such as Styrofoam, and fiber glass among others. PRSN traditionally uses Styrofoam boxes to cover their seismic sensors, however, a proper procedure to test how these method compare to other new techniques has never been approached. The deficiency of properly testing these techniques in the Caribbean and especially Puerto Rico is that these thermal fluctuations still happen because of the intense sun and humidity. We conducted a test based on the methods employed by the IRIS Transportable Array, based on insulation by sand burial of

  20. Regulatory mechanism of endothelin receptor B in the cerebral arteries after focal cerebral ischemia

    DEFF Research Database (Denmark)

    Grell, Anne-Sofie; Thigarajah, Rushani; Edvinsson, Lars

    2014-01-01

    BACKGROUND AND PURPOSE: Increased expression of endothelin receptor type B (ETBR), a vasoactive receptor, has recently been implied in the reduced cerebral blood flow and exacerbated neuronal damage after ischemia-reperfusion (I/R). The study explores the regulatory mechanisms of ETBR to identify...... drug targets to restore normal cerebral artery contractile function as part of successful neuroprotective therapy. METHODS: We have employed in vitro methods on human and rat cerebral arteries to study the regulatory mechanisms and the efficacy of target selective inhibitor, Mithramycin A (Mit...... the ETBR mRNA and protein levels. It also significantly reduced the ETBR mediated cerebrovascular contractility. Detailed analysis indicated that ERK1/2 mediated phosphorylation of Sp1 might be essential for ETBR transcription. CONCLUSION: Transcription factor Sp1 regulates the ETBR mediated...

  1. Focal myositis

    Energy Technology Data Exchange (ETDEWEB)

    Kransdorf, M.J. [Saint Mary`s Hospital, Richmond, VA (United States). Dept. of Radiol.]|[Department of Radiologic Pathology, Armed Forces Institute of Pathology, Washington, DC (United States); Temple, H.T. [Department of Orthopedic Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia (United States)]|[Department of Orthopedic Pathology, Armed Forces Institute of Pathology, Washington, DC (United States); Sweet, D.E. [Department of Orthopedic Pathology, Armed Forces Institute of Pathology, Washington, DC (United States)

    1998-05-01

    Focal myositis is a pseudotumor of soft tissue that typically occurs in the deep soft tissue of the extremities, and is a relatively rare lesion. There is a wide clinical spectrum, with approximately one-third of patients with focal myositis subsequently developing polymyositis, and clinical symptoms of generalized weakness, fever, myalgia, and weight loss, with elevation of creatine phosphokinase. We report the case of a patient with focal myositis who subsequently developed myositis ossificans-like features. (orig.) With 3 figs., 25 refs.

  2. Focal and Reentrant Mechanisms of Torsades de Pointes: EAD, Reentry, or Chimera?

    Directory of Open Access Journals (Sweden)

    Yuji Murakawa, MD

    2011-01-01

    Full Text Available Torsades de pointes (TdP. is characterized not only by its electrocardiographic morphology but also by a tendency to spontaneously terminate. Although clinical and experimental studies suggested that TdP is triggered exclusively by early afterdepolarization, the reentrant mechanism seems to play a certain role in its maintenance. In this article, I review the studies that investigated the origin and activation sequences of the twisting QRS complexes of TdP, and discuss whether it is fortunate or unfortunate for us if TdP has something to do with reentry.

  3. Astragaloside IV for Experimental Focal Cerebral Ischemia: Preclinical Evidence and Possible Mechanisms

    Directory of Open Access Journals (Sweden)

    Hui-Lin Wang

    2017-01-01

    Full Text Available Astragaloside IV (AST-IV is a principal component of Radix Astragali seu Hedysari (Huangqi and exerts potential neuroprotection in experimental ischemic stroke. Here, we systematically assessed the effectiveness and possible mechanisms of AST-IV for experimental acute ischemic stroke. An electronic search in eight databases was conducted from inception to March 2016. The study quality score was evaluated using the CAMARADES. Rev Man 5.0 software was used for data analyses. Thirteen studies with 244 animals were identified. The study quality score of included studies ranged from 3/10 to 8/10. Eleven studies showed significant effects of AST-IV for ameliorating the neurological function score (P<0.05; seven studies for reducing the infarct volume (P<0.05; and three or two studies for reducing the brain water content and Evans blue leakage (P<0.05, respectively, compared with the control. The mechanisms of AST-IV for ischemic stroke are multiple such as antioxidative/nitration stress reaction, anti-inflammatory, and antiapoptosis. In conclusion, the findings of present study indicated that AST-IV could improve neurological deficits and infarct volume and reduce the blood-brain barrier permeability in experimental cerebral ischemia despite some methodological flaws. Thus, AST-IV exerted a possible neuroprotective effect during the cerebral ischemia/reperfusion injury largely through its antioxidant, anti-inflammatory, and antiapoptosis properties.

  4. Effects of cue focality on the neural mechanisms of prospective memory: A meta-analysis of neuroimaging studies.

    Science.gov (United States)

    Cona, Giorgia; Bisiacchi, Patrizia Silvia; Sartori, Giuseppe; Scarpazza, Cristina

    2016-05-17

    Remembering to execute pre-defined intentions at the appropriate time in the future is typically referred to as Prospective Memory (PM). Studies of PM showed that distinct cognitive processes underlie the execution of delayed intentions depending on whether the cue associated with such intentions is focal to ongoing activity processing or not (i.e., cue focality). The present activation likelihood estimation (ALE) meta-analysis revealed several differences in brain activity as a function of focality of the PM cue. The retrieval of intention is supported mainly by left anterior prefrontal cortex (Brodmann Area, BA 10) in nonfocal tasks, and by cerebellum and ventral parietal regions in focal tasks. Furthermore, the precuneus showed increased activation during the maintenance phase of intentions compared to the retrieval phase in nonfocal tasks, whereas the inferior parietal lobule showed increased activation during the retrieval of intention compared to maintenance phase in the focal tasks. Finally, the retrieval of intention relies more on the activity in anterior cingulate cortex for nonfocal tasks, and on posterior cingulate cortex for focal tasks. Such focality-related pattern of activations suggests that prospective remembering is mediated mainly by top-down and stimulus-independent processes in nonfocal tasks, whereas by more automatic, bottom-up, processes in focal tasks.

  5. Neuroprotective mechanism of BNG-1 against focal cerebral ischemia: a neuroimaging and neurotrophin study.

    Science.gov (United States)

    Chi, Nai-Fang; Liu, Ho-Ling; Yang, Jen-Tsung; Lin, Jr-Rung; Liao, Shu-Li; Peng, Bo-Han; Lee, Yen-Tung; Lee, Tsong-Hai

    2014-01-01

    BNG-1 is a herb complex used in traditional Chinese medicine to treat stroke. In this study, we attempted to identify the neuroprotective mechanism of BNG-1 by using neuroimaging and neurotrophin analyses of a stroke animal model. Rats were treated with either saline or BNG-1 for 7 d after 60-min middle cerebral artery occlusion by filament model. The temporal change of magnetic resonance (MR) imaging of brain was studied using a 7 Tesla MR imaging (MRI) system and the temporal expressions of neurotrophin-3 (NT-3), brain-derived neurotrophic factor (BDNF), and nerve growth factor (NGF) in brain were analyzed before operation and at 4 h, 2 d, and 7 d after operation. Compared with the saline group, the BNG-1 group exhibited a smaller infarction volume in the cerebral cortex in T2 image from as early as 4 h to 7 d, less edema in the cortex in diffusion weighted image from 2 to 7 d, earlier reduction of postischemic hyperperfusion in both the cortex and striatum in perfusion image at 4 h, and earlier normalization of the ischemic pattern in the striatum in susceptibility weighted image at 2 d. NT-3 and BDNF levels were higher in the BNG-1 group than the saline group at 7 d. We concluded that the protective effect of BNG-1 against cerebral ischemic injury might act through improving cerebral hemodynamics and recovering neurotrophin generation.

  6. The Amorgos, Greece earthquake and tsunami of 09 July 1956: Focal mechanism and field survey

    Science.gov (United States)

    Okal, E. A.; Synolakis, C. E.; Yalciner, A. C.

    2004-12-01

    The earthquake of 09 July 1956 near the Greek island of Amorgos (M sub PAS = 7.8) is the largest event of the past 75 years in the Aegean. It created the most damaging tsunami to hit Greece in the past century, with reported run-up of 25 m on the Eastern coast of Amorgos. This prompted Ambraseys [1960] to propose that underwater landslides may have occurred. We use the PDFM method introduced by Reymond and Okal [2000] to invert a moment tensor from a limited set of spectral amplitudes of mantle waves. Our solution features a normal faulting mechanism (phi = 245 deg; delta = 67 deg; lambda = 281 deg.) and a moment of 3.9 * 10**27 dyn-cm. In parallel, we have started a systematic survey of tsunami run-up heights in the Aegean Islands and the Asia Minor coast of Turkey, through the interview of elderly witnesses of the tsunami. Our growing dataset presently includes 29 data points on seven islands and at eight villages on the Turkish Coast. We confirm a single run-up value of 20 m on Eastern Amorgos, with measured run-up limited to 8 m on Astypalea and at most 3 m at other locations (1 m on the Turkish coast). The uniqueness of the large run-up value, in the proximity of locales with milder values, does suggest that it could be due to the influence of a localized underwater landslide.

  7. A Statistical Study on VLF Subionospheric Perturbations Associated with Major Earthquakes: A View from Focal Mechanism

    Science.gov (United States)

    Kawano, T.; Tatsuta, K.; Hobara, Y.

    2015-12-01

    Continuous monitoring of signal amplitudes of worldwide VLF transmitters is a powerful tool to study the lower ionospheric condition. Although, lower ionospheric perturbations prior to some of the major earthquakes have been reported for years, their occurrence and coupling mechanism between the ground and overlaying ionosphere prior to the earthquakes are not clear yet. In this paper, we carried out a statistical analysis based on the nighttime averaged signal amplitude data from the UEC's VLF/LF transmitter observation network. Two hundred forty three earthquakes were occurred within the 5th Fresnel zone of transmitter-receiver paths around Japan during the time period of 2007 to 2012. These earthquakes were characterized into three different groups based on the Centroid-Moment-Tensor (CMT) solution such as reverse fault type, normal fault type and stress slip type. The ionospheric anomaly was identified by a large change in the VLF/LF amplitude during nighttime. As a result, we found the ionospheric perturbations associated with both ground and sea earthquakes. Remarkably, the reverse fault type earthquakes have the highest occurrence rate of ionospheric perturbation among the three types both for sea (41%) and ground events (61%). The occurrence rates for normal type fault are 35% and 56% for sea and ground earthquakes respectively and the same for stress slip type are 39% and 20% for sea and ground earthquakes respectively. In both cases the occurrence rates are smaller than the reverse fault type. The clear difference of occurrence rate of the ionospheric perturbations may indicate that the coupling efficiency of seismic activity into the overlaying ionosphere is controlled by the pressure in the earth's crust. This gives us further physical insight of Lithosphere-Atmosphere-Ionosphere (LAI) coupling processes.

  8. Oncogenic Receptor Tyrosine Kinases Directly Phosphorylate Focal Adhesion Kinase (FAK) as a Resistance Mechanism to FAK-Kinase Inhibitors.

    Science.gov (United States)

    Marlowe, Timothy A; Lenzo, Felicia L; Figel, Sheila A; Grapes, Abigail T; Cance, William G

    2016-12-01

    Focal adhesion kinase (FAK) is a major drug target in cancer and current inhibitors targeted to the ATP-binding pocket of the kinase domain have entered clinical trials. However, preliminary results have shown limited single-agent efficacy in patients. Despite these unfavorable data, the molecular mechanisms that drive intrinsic and acquired resistance to FAK-kinase inhibitors are largely unknown. We have demonstrated that receptor tyrosine kinases (RTK) can directly bypass FAK-kinase inhibition in cancer cells through phosphorylation of FAK's critical tyrosine 397 (Y397). We also showed that HER2 forms a direct protein-protein interaction with the FAK-FERM-F1 lobe, promoting direct phosphorylation of Y397. In addition, FAK-kinase inhibition induced two forms of compensatory RTK reprogramming: (i) the rapid phosphorylation and activation of RTK signaling pathways in RTK High cells and (ii) the long-term acquisition of RTKs novel to the parental cell line in RTK Low cells. Finally, HER2 +: cancer cells displayed resistance to FAK-kinase inhibition in 3D growth assays using a HER2 isogenic system and HER2 + cancer cell lines. Our data indicate a novel drug resistance mechanism to FAK-kinase inhibitors whereby HER2 and other RTKs can rescue and maintain FAK activation (pY397) even in the presence of FAK-kinase inhibition. These data may have important ramifications for existing clinical trials of FAK inhibitors and suggest that individual tumor stratification by RTK expression would be important to predict patient response to FAK-kinase inhibitors. Mol Cancer Ther; 15(12); 3028-39. ©2016 AACR. ©2016 American Association for Cancer Research.

  9. A Comparison between Deep and Shallow Stress Fields in Korea Using Earthquake Focal Mechanism Inversions and Hydraulic Fracturing Stress Measurements

    Science.gov (United States)

    Lee, Rayeon; Chang, Chandong; Hong, Tae-kyung; Lee, Junhyung; Bae, Seong-Ho; Park, Eui-Seob; Park, Chan

    2016-04-01

    We are characterizing stress fields in Korea using two types of stress data: earthquake focal mechanism inversions (FMF) and hydraulic fracturing stress measurements (HF). The earthquake focal mechanism inversion data represent stress conditions at 2-20 km depths, whereas the hydraulic fracturing stress measurements, mostly conducted for geotechnical purposes, have been carried out at depths shallower than 1 km. We classified individual stress data based on the World Stress Map quality ranking scheme. A total of 20 FMF data were classified into A-B quality, possibly representing tectonic stress fields. A total of 83 HF data out of compiled 226 data were classified into B-C quality, which we use for shallow stress field characterization. The tectonic stress, revealed from the FMF data, is characterized by a remarkable consistency in its maximum stress (σ1) directions in and around Korea (N79±2° E), indicating a quite uniform deep stress field throughout. On the other hand, the shallow stress field, represented by HF data, exhibits local variations in σ1 directions, possibly due to effects of topography and geologic structures such as faults. Nonetheless, there is a general similarity in σ1 directions between deep and shallow stress fields. To investigate the shallow stress field statistically, we follow 'the mean orientation and wavelength analysis' suggested by Reiter et al. (2014). After the stress pattern analysis, the resulting stress points distribute sporadically over the country, not covering the entire region evenly. In the western part of Korea, the shallow σ1directions are generally uniform with their search radius reaching 100 km, where the average stress direction agrees well with those of the deep tectonic stress. We note two noticeable differences between shallow and deep stresses in the eastern part of Korea. First, the shallow σ1 orientations are markedly non-uniform in the southeastern part of Korea with their search radius less than 25 km

  10. High-resolution fault image from accurate locations and focal mechanisms of the 2008 swarm earthquakes in West Bohemia, Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Vavryčuk, Václav; Bouchaala, Fateh; Fischer, Tomáš

    2013-01-01

    Roč. 590, April (2013), s. 189-195 ISSN 0040-1951 R&D Projects: GA ČR(CZ) GAP210/12/1491; GA MŠk LM2010008 EU Projects: European Commission(XE) 230669 - AIM Institutional support: RVO:67985530 Keywords : earth quake location * failure criterion * fault friction * focal mechanism * tectonic stress Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 2.866, year: 2013

  11. Focal mechanisms in the southern Aegean from temporary seismic networks – implications for the regional stress field and ongoing deformation processes

    OpenAIRE

    Friederich, W.; Brüstle, A.; Küperkoch, L.; Meier, T.; Lamara, S.; Working Group, Egelados

    2014-01-01

    The lateral variation of the stress field in the southern Aegean plate and the subducting Hellenic slab is determined from recordings of seismicity obtained with the CYCNET and EGELADOS networks in the years from 2002 to 2007. First motions from 7000 well-located microearthquakes were analysed to produce 540 well-constrained focal mechanisms. They were complemented by another 140 derived by waveform matching of records from larger events. Most of these earth...

  12. Focal mechanisms and moment magnitudes of micro-earthquakes in central Brazil by waveform inversion with quality assessment and inference of the local stress field

    Science.gov (United States)

    Carvalho, Juraci; Barros, Lucas Vieira; Zahradník, Jiří

    2016-11-01

    This paper documents an investigation on the use of full waveform inversion to retrieve focal mechanisms of 11 micro-earthquakes (Mw 0.8 to 1.4). The events represent aftershocks of a 5.0 mb earthquake that occurred on October 8, 2010 close to the city of Mara Rosa in the state of Goiás, Brazil. The main contribution of the work lies in demonstrating the feasibility of waveform inversion of such weak events. The inversion was made possible thanks to recordings available at 8 temporary seismic stations in epicentral distances of less than 8 km, at which waveforms can be successfully modeled at relatively high frequencies (1.5-2.0 Hz). On average, the fault-plane solutions obtained are in agreement with a composite focal mechanism previously calculated from first-motion polarities. They also agree with the fault geometry inferred from precise relocation of the Mara Rosa aftershock sequence. The focal mechanisms provide an estimate of the local stress field. This paper serves as a pilot study for similar investigations in intraplate regions where the stress-field investigations are difficult due to rare earthquake occurrences, and where weak events must be studied with a detailed quality assessment.

  13. Focal mechanisms in the southern Aegean from temporary seismic networks - implications for the regional stress field and ongoing deformation processes

    Science.gov (United States)

    Friederich, W.; Brüstle, A.; Küperkoch, L.; Meier, T.; Lamara, S.; Egelados Working Group

    2014-05-01

    The lateral variation of the stress field in the southern Aegean plate and the subducting Hellenic slab is determined from recordings of seismicity obtained with the CYCNET and EGELADOS networks in the years from 2002 to 2007. First motions from 7000 well-located microearthquakes were analysed to produce 540 well-constrained focal mechanisms. They were complemented by another 140 derived by waveform matching of records from larger events. Most of these earthquakes fall into 16 distinct spatial clusters distributed over the southern Aegean region. For each cluster, a stress inversion could be carried out yielding consistent estimates of the stress field and its spatial variation. At crustal levels, the stress field is generally dominated by a steeply dipping compressional principal stress direction except in places where coupling of the subducting slab and overlying plate come into play. Tensional principal stresses are generally subhorizontal. Just behind the forearc, the crust is under arc-parallel tension whereas in the volcanic areas around Kos, Columbo and Astypalea tensional and intermediate stresses are nearly degenerate. Further west and north, in the Santorini-Amorgos graben and in the area of the islands of Mykonos, Andros and Tinos, tensional stresses are significant and point around the NW-SE direction. Very similar stress fields are observed in western Turkey with the tensional axis rotated to NNE-SSW. Intermediate-depth earthquakes below 100 km in the Nisyros region indicate that the Hellenic slab experiences slab-parallel tension at these depths. The direction of tension is close to east-west and thus deviates from the local NW-oriented slab dip presumably owing to the segmentation of the slab. Beneath the Cretan sea, at shallower levels, the slab is under NW-SE compression. Tensional principal stresses in the crust exhibit very good alignment with extensional strain rate principal axes derived from GPS velocities except in volcanic areas, where both

  14. The Mechanical Design of a Kinematic Mount for the Mid Infrared Instrument Focal Plane Module on the James Webb Space Telescope

    Science.gov (United States)

    Thelen, Michael P.; Moore, Donald M.

    2009-01-01

    The detector assembly for the Mid Infrared Instrument (MIRI) of the James Webb Space Telescope (JWST) is mechanically supported in the Focal Plane Module (FPM) Assembly with an efficient hexapod design. The kinematic mount design allows for precision adjustment of the detector boresight to assembly alignment fiducials and maintains optical alignment requirements during flight conditions of launch and cryogenic operations below 7 Kelvin. This kinematic mounting technique is able to be implemented in a variety of optical-mechanical designs and is capable of micron level adjustment control and stability over wide dynamic and temperature ranges.

  15. Earthquake Rupture at Focal Depth, Part I: Structure and Rupture of the Pretorius Fault, TauTona Mine, South Africa

    Science.gov (United States)

    Heesakkers, V.; Murphy, S.; Reches, Z.

    2011-12-01

    We analyze the structure of the Archaean Pretorius fault in TauTona mine, South Africa, as well as the rupture-zone that recently reactivated it. The analysis is part of the Natural Earthquake Laboratory in South African Mines (NELSAM) project that utilizes the access to 3.6 km depth provided by the mining operations. The Pretorius fault is a ~10 km long, oblique-strike-slip fault with displacement of up to 200 m that crosscuts fine to very coarse grain quartzitic rocks in TauTona mine. We identify here three structural zones within the fault-zone: (1) an outer damage zone, ~100 m wide, of brittle deformation manifested by multiple, widely spaced fractures and faults with slip up to 3 m; (2) an inner damage zone, 25-30 m wide, with high density of anastomosing conjugate sets of fault segments and fractures, many of which carry cataclasite zones; and (3) a dominant segment, with a cataclasite zone up to 50 cm thick that accommodated most of the Archaean slip of the Pretorius fault, and is regarded as the `principal slip zone' (PSZ). This fault-zone structure indicates that during its Archaean activity, the Pretorius fault entered the mature fault stage in which many slip events were localized along a single, PSZ. The mining operations continuously induce earthquakes, including the 2004, M2.2 event that rejuvenated the Pretorius fault in the NELSAM project area. Our analysis of the M2.2 rupture-zone shows that (1) slip occurred exclusively along four, pre-existing large, quasi-planer segments of the ancient fault-zone; (2) the slipping segments contain brittle cataclasite zones up to 0.5 m thick; (3) these segments are not parallel to each other; (4) gouge zones, 1-5 mm thick, composed of white `rock-flour' formed almost exclusively along the cataclasite-host rock contacts of the slipping segments; (5) locally, new, fresh fractures branched from the slipping segments and propagated in mixed shear-tensile mode; (6) the maximum observed shear displacement is 25 mm in

  16. A new strategy for earthquake focal mechanisms using waveform-correlation-derived relative polarities and cluster analysis: Application to the 2014 Long Valley Caldera earthquake swarm

    Science.gov (United States)

    Shelly, David R.; Hardebeck, Jeanne L.; Ellsworth, William L.; Hill, David P.

    2016-01-01

    In microseismicity analyses, reliable focal mechanisms can typically be obtained for only a small subset of located events. We address this limitation here, presenting a framework for determining robust focal mechanisms for entire populations of very small events. To achieve this, we resolve relative P and S wave polarities between pairs of waveforms by using their signed correlation coefficients—a by-product of previously performed precise earthquake relocation. We then use cluster analysis to group events with similar patterns of polarities across the network. Finally, we apply a standard mechanism inversion to the grouped data, using either catalog or correlation-derived P wave polarity data sets. This approach has great potential for enhancing analyses of spatially concentrated microseismicity such as earthquake swarms, mainshock-aftershock sequences, and industrial reservoir stimulation or injection-induced seismic sequences. To demonstrate its utility, we apply this technique to the 2014 Long Valley Caldera earthquake swarm. In our analysis, 85% of the events (7212 out of 8494 located by Shelly et al. [2016]) fall within five well-constrained mechanism clusters, more than 12 times the number with network-determined mechanisms. Of the earthquakes we characterize, 3023 (42%) have magnitudes smaller than 0.0. We find that mechanism variations are strongly associated with corresponding hypocentral structure, yet mechanism heterogeneity also occurs where it cannot be resolved by hypocentral patterns, often confined to small-magnitude events. Small (5–20°) rotations between mechanism orientations and earthquake location trends persist when we apply 3-D velocity models and might reflect a geometry of en echelon, interlinked shear, and dilational faulting.

  17. Identification of Focal Mechanisms of Seisms Occurring in the San Salvador Volcano-Ilopango Lake Area Between 1994 and March 2005

    International Nuclear Information System (INIS)

    Maria Mendez Martinez, Luz de; Portillo, Mercy

    2009-01-01

    We studied the geographic area located in the central part of El Salvador, between the San Salvador Volcano (Quezaltepec) and Ilopango Lake. Its latitude is between 13 deg. 36' and 13 deg. 54', and longitude is between -89 deg. 18' and -88 deg. 57'. This area is directly affected by the WNW axis, the most prominent weak tectonic system in the region. Our research aimed to determine the focal mechanisms of seisms occurring in the studied area between 1994 and March 2005. Our analysis provided information about displacement types of the geological faults, using the wave impulse P method and computer applications ARCGIS and SEISAN, with the subroutine FOCMEC. Information of the studied seisms was obtained from the National Service of Territorial Studies (SNET) database. Geographic models used in the preparation of maps are from the geographic information system of the School of Physics at the University of El Salvador. The 37 focal mechanisms on the map of faults were identified in digital seismographs to determinate the arrival polarity of the wave P for each seism station. Data from the focal mechanisms were analyzed and correlated with their replications. The analysis allowed us to identify evidences to consider the fault continuity not reported by the last geological mission in El Salvador conducted in the 1970s. The fault continuity is located northwest of the studied geographical area, between San Salvador City and the San Salvador Volcano. The compression and strain axes for this area are two main horizontal force axes. The average orientation for the strain axis is NNE-SSW, and WNW-SEE for the compression axis. There is also important seismic activity in the Ilopango Lake and surrounding area. However, data did not allow us to make any inference. The tensors distribution resulted in a high dispersion corresponding to typical fauces models.

  18. Analysis of the recent Plio-Quaternary deformation and the correlation with the focal mechanisms of the significant earthquakes in the Bokoya, Ras Tarf (Eastern Rif

    Directory of Open Access Journals (Sweden)

    El Mahsani A.

    2018-01-01

    surface. A reduced number of faults shows a generall direction NNE-SSO to N-S through the Quaternary formations in the NO of Al Hoceima city, the direction NO does not show a good correlation with the directions of surface rupture, as well as with the deducted directions from focals mechanisms. This study drives us to propose that faults of direction NNE-SSO to NE-SO, represent the major directions of the faults in the Al Hoceima region, which represents the main cause of the seismic activity in the region.

  19. Opto-mechanical design and development status of an all spherical five lenses focal reducer for the 2.3 m Thai National Telescope

    Science.gov (United States)

    Buisset, Christophe; Prasit, Apirat; Lépine, Thierry; Poshyachinda, Saran; Soonthornthum, Boonrucksar; Deboos, Alexis

    2016-07-01

    The National Astronomical Research Institute (NARIT) is currently developing an all spherical five lenses focal reducer to image a FOV circular of diameter Δθ = 14.6' on the 4K camera with a pixel scale equal to 0.42''/pixel. The spatial resolution will be better than 1.2'' over the full visible spectral domain [400 nm, 800 nm]. The relative irradiance between the ghost and the science images will be lower than 10-4. The maximum distortion will be lower than 1% and the maximum angle of incidence on the filters will be equal to 8°. The focal reducer comprises 1 doublet L1 located at the fork entrance and 1 triplet L2 located in front of the camera. The doublet L1 will be mounted on a tip-tilt mount placed on a robotic sliding rail. L1 will thus be placed in the optical path during the observations with the 4K camera and will be removed during the observations with the other instruments. The triplet L2 will be installed on the instrument cube in front of the camera equipped with the filter wheel. The glass will be manufactured in a specialized company, the mechanical parts will be manufactured by using the NARIT Computer Numerical Control machine and the lenses will be integrated at NARIT. In this paper, we describe the optical and mechanical designs and we present the geometrical performance, the transmission budget and the results of the stray light analyses.

  20. Mechanisms underlying the attachment and spreading of human osteoblasts: from transient interactions to focal adhesions on vitronectin-grafted bioactive surfaces.

    Science.gov (United States)

    Brun, Paola; Scorzeto, Michele; Vassanelli, Stefano; Castagliuolo, Ignazio; Palù, Giorgio; Ghezzo, Francesca; Messina, Grazia M L; Iucci, Giovanna; Battaglia, Valentina; Sivolella, Stefano; Bagno, Andrea; Polzonetti, Giovanni; Marletta, Giovanni; Dettin, Monica

    2013-04-01

    The features of implant devices and the reactions of bone-derived cells to foreign surfaces determine implant success during osseointegration. In an attempt to better understand the mechanisms underlying osteoblasts attachment and spreading, in this study adhesive peptides containing the fibronectin sequence motif for integrin binding (Arg-Gly-Asp, RGD) or mapping the human vitronectin protein (HVP) were grafted on glass and titanium surfaces with or without chemically induced controlled immobilization. As shown by total internal reflection fluorescence microscopy, human osteoblasts develop adhesion patches only on specifically immobilized peptides. Indeed, cells quickly develop focal adhesions on RGD-grafted surfaces, while HVP peptide promotes filopodia, structures involved in cellular spreading. As indicated by immunocytochemistry and quantitative polymerase chain reaction, focal adhesions kinase activation is delayed on HVP peptides with respect to RGD while an osteogenic phenotypic response appears within 24h on osteoblasts cultured on both peptides. Cellular pathways underlying osteoblasts attachment are, however, different. As demonstrated by adhesion blocking assays, integrins are mainly involved in osteoblast adhesion to RGD peptide, while HVP selects osteoblasts for attachment through proteoglycan-mediated interactions. Thus an interfacial layer of an endosseous device grafted with specifically immobilized HVP peptide not only selects the attachment and supports differentiation of osteoblasts but also promotes cellular migration. Copyright © 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  1. Mechanical stimuli on C2C12 myoblasts affect myoblast differentiation, focal adhesion kinase phosphorylation and galectin-1 expression

    DEFF Research Database (Denmark)

    Grossi, Alberto Blak; Lametsch, Rene; Karlsson, Anders H

    2011-01-01

    Mechanical forces are crucial in the regulation of cell morphology and function. At the cellular level, these forces influence myoblast differentiation and fusion. In this study we applied mechanical stimuli to embryonic muscle cells using magnetic microbeads, a method shown to apply stress...... by mechanical stimulation including Galectin-1, Annexin III, and RhoGDI. In this study we demonstrate how the combination of this method of mechanical stimuli and proteomic analysis can be a powerful tool to detect proteins that are potentially interacting in biochemical pathways or complex cellular mechanisms...... during the process of myoblast differentiation. We determined an increase in expression and changes in cellular localization of Galectin-1, in mechanically stimulated myoblasts. A potential involvement of Galectin-1 in myoblast differentiation is presented....

  2. Determination of focal mechanisms of intermediate-magnitude earthquakes in Mexico, based on Greens functions calculated for a 3D Earth model

    Science.gov (United States)

    Rodrigo Rodríguez Cardozo, Félix; Hjörleifsdóttir, Vala

    2015-04-01

    One important ingredient in the study of the complex active tectonics in Mexico is the analysis of earthquake focal mechanisms, or the seismic moment tensor. They can be determined trough the calculation of Green functions and subsequent inversion for moment-tensor parameters. However, this calculation is gets progressively more difficult as the magnitude of the earthquakes decreases. Large earthquakes excite waves of longer periods that interact weakly with laterally heterogeneities in the crust. For these earthquakes, using 1D velocity models to compute the Greens fucntions works well. The opposite occurs for smaller and intermediate sized events, where the relatively shorter periods excited interact strongly with lateral heterogeneities in the crust and upper mantle and requires more specific or regional 3D models. In this study, we calculate Greens functions for earthquakes in Mexico using a laterally heterogeneous seismic wave speed model, comprised of mantle model S362ANI (Kustowski et al 2008) and crustal model CRUST 2.0 (Bassin et al 1990). Subsequently, we invert the observed seismograms for the seismic moment tensor using a method developed by Liu et al (2004) an implemented by Óscar de La Vega (2014) for earthquakes in Mexico. By following a brute force approach, in which we include all observed Rayleigh and Love waves of the Mexican National Seismic Network (Servicio Sismológico Naciona, SSN), we obtain reliable focal mechanisms for events that excite a considerable amount of low frequency waves (Mw > 4.8). However, we are not able to consistently estimate focal mechanisms for smaller events using this method, due to high noise levels in many of the records. Excluding the noisy records, or noisy parts of the records manually, requires interactive edition of the data, using an efficient tool for the editing. Therefore, we developed a graphical user interface (GUI), based on python and the python library ObsPy, that allows the edition of observed and

  3. Earthquake rupture at focal depth, part II: mechanics of the 2004 M2.2 earthquake along the Pretorius Fault, TauTona Mine, South Africa

    Science.gov (United States)

    Heesakkers, V.; Murphy, S.; Lockner, D.A.; Reches, Z.

    2011-01-01

    We analyze here the rupture mechanics of the 2004, M2.2 earthquake based on our observations and measurements at focal depth (Part I). This event ruptured the Archean Pretorius fault that has been inactive for at least 2 Ga, and was reactivated due to mining operations down to a depth of 3.6 km depth. Thus, it was expected that the Pretorius fault zone will fail similarly to an intact rock body independently of its ancient healed structure. Our analysis reveals a few puzzling features of the M2.2 rupture-zone: (1) the earthquake ruptured four, non-parallel, cataclasite bearing segments of the ancient Pretorius fault-zone; (2) slip occurred almost exclusively along the cataclasite-host rock contacts of the slipping segments; (3) the local in-situ stress field is not favorable to slip along any of these four segments; and (4) the Archean cataclasite is pervasively sintered and cemented to become brittle and strong. To resolve these observations, we conducted rock mechanics experiments on the fault-rocks and host-rocks and found a strong mechanical contrast between the quartzitic cataclasite zones, with elastic-brittle rheology, and the host quartzites, with damage, elastic–plastic rheology. The finite-element modeling of a heterogeneous fault-zone with the measured mechanical contrast indicates that the slip is likely to reactivate the ancient cataclasite-bearing segments, as observed, due to the strong mechanical contrast between the cataclasite and the host quartzitic rock.

  4. Mechanical stimulation of C2C12 cells increases m-calpain expression and activity, focal adhesion plaque degradation and cell fusion

    DEFF Research Database (Denmark)

    Grossi, Alberto; Karlsson, Anders Hans; Lawson, Moira A.

    2005-01-01

    Abstract Mechanical Stimulation of C2C12 Cells Increases m-calpain Expression and Activity, Focal Adhesion Plaque Degradation and Cell Fusion A. Grossi, A. H. Karlsson, M. A. Lawson; Department of Dairy and Food Science, Royal Veterinary and Agricultural University, Frederiksberg C, Denmark...... Myogenesis is a complex sequence of events, including the irreversible transition from the proliferation-competent myoblast stage into fused, multinucleated myotubes. During embryonic development, myogenic differentiation is regulated by positive and negative signals from surrounding tissues. Stimulation due...... to the activity of ubiquitous proteolytic enzymes known as calpains has been reported. Whether there is a link between stretch- or load induced signaling and calpain expression and activation is not known. Using a magnetic bead stimulation assay and C2C12 mouse myoblasts cell population, we have demonstrated...

  5. Periodontitis in patients with focal tuberculosis

    Directory of Open Access Journals (Sweden)

    Alexandrova Е.А.

    2010-12-01

    Full Text Available The research goal is to investigate the mechanisms of formation and peculiarities of periodontitis in patients with focal tuberculosis. Patients with periodontitis and focal tuberculosis are proved to develop local inflammatory reaction with increased infection and activation of proinflammatory cytokines in parodontal pockets fluid. The main risk factor of frequent and durable recurrence of parodontal pathology in case of focal tuberculosis was the development of pathologic process as a cause of disbalance of lipid peroxidation and antioxidant system, endotoxicosis syndrome

  6. Tectonic Implication of the 5th March 2005, Doublet Earthquake in Ilan, Taiwan

    Directory of Open Access Journals (Sweden)

    En-Chao Yeh

    2016-01-01

    Full Text Available The 5th March 2005 earthquake doublet focal mechanism was determined as strike-slip faulting from Harvard and BATS moment tensor inversion. However, based on first motion polarities, the first shock has a normal focal mechanism (Wu et al. 2008a. This discrepancy has caused a debate over the focal mechanism solution because different focal mechanisms have different tectonic implications. Based on the dislocation determination from Global Position System (GPS measurements, we find this event includes both tensile and strike-slip components. This finding illustrates the reason for the differences in the determined focal mechanisms using two different types of seismic data and analyzing methods. Field mapping and microstructure examination results indicate that the ductile deformation around the study area was characterized by the evolution from transpression to transtension with a predominant strike-slip component, but present-day active structures may be dominated by normal faulting. Thus, the active tensile slip result determined from dislocation modeling strongly suggests that the back arc extension of the Okinawa trough influences the stress state in this region, and changes the major transtension from strike-slip faulting to normal faulting.

  7. Focal mechanisms and inter-event times of low-frequency earthquakes reveal quasi-continuous deformation and triggered slow slip on the deep Alpine Fault

    Science.gov (United States)

    Baratin, Laura-May; Chamberlain, Calum J.; Townend, John; Savage, Martha K.

    2018-02-01

    Characterising the seismicity associated with slow deformation in the vicinity of the Alpine Fault may provide constraints on the stresses acting on a major transpressive margin prior to an anticipated great (≥M8) earthquake. Here, we use recently detected tremor and low-frequency earthquakes (LFEs) to examine how slow tectonic deformation is loading the Alpine Fault late in its typical ∼300-yr seismic cycle. We analyse a continuous seismic dataset recorded between 2009 and 2016 using a network of 10-13 short-period seismometers, the Southern Alps Microearthquake Borehole Array. Fourteen primary LFE templates are used in an iterative matched-filter and stacking routine, allowing the detection of similar signals corresponding to LFE families sharing common locations. This yields an 8-yr catalogue containing 10,000 LFEs that are combined for each of the 14 LFE families using phase-weighted stacking to produce signals with the highest possible signal-to-noise ratios. We show that LFEs occur almost continuously during the 8-yr study period and highlight two types of LFE distributions: (1) discrete behaviour with an inter-event time exceeding 2 min; (2) burst-like behaviour with an inter-event time below 2 min. We interpret the discrete events as small-scale frequent deformation on the deep extent of the Alpine Fault and LFE bursts (corresponding in most cases to known episodes of tremor or large regional earthquakes) as brief periods of increased slip activity indicative of slow slip. We compute improved non-linear earthquake locations using a 3-D velocity model. LFEs occur below the seismogenic zone at depths of 17-42 km, on or near the hypothesised deep extent of the Alpine Fault. The first estimates of LFE focal mechanisms associated with continental faulting, in conjunction with recurrence intervals, are consistent with quasi-continuous shear faulting on the deep extent of the Alpine Fault.

  8. Slab Geometry and Deformation in the Northern Nazca Subduction Zone Inferred From The Relocation and Focal mechanisms of Intermediate-Depth Earthquakes

    Science.gov (United States)

    Chang, Y.; Warren, L. M.; Prieto, G. A.

    2015-12-01

    In the northern Nazca subduction zone, the Nazca plate is subducting to the east beneath the South American Plate. At ~5.6ºN, the subducting plate has a 240-km east-west offset associated with a slab tear, called the Caldas tear, that separates the northern and southern segments. Our study seeks to better define the slab geometry and deformation in the southern segment, which has a high rate of intermediate-depth earthquakes (50-300 km) between 3.6ºN and 5.2ºN in the Cauca cluster. From Jan 2010 to Mar 2014, 228 intermediate-depth earthquakes in the Cauca cluster with local magnitude Ml 2.5-4.7 were recorded by 65 seismic stations of the Colombian National Seismic Network. We review and, if necessary, adjust the catalog P and S wave arrival picks. We use the travel times to relocate the earthquakes using a double difference relocation method. For earthquakes with Ml ≥3.8, we also use waveform modeling to compute moment tensors . The distribution of earthquake relocations shows an ~15-km-thick slab dipping to the SE. The dip angle increases from 20º at the northern edge of the cluster to 38º at the southern edge. Two concentrated groups of earthquakes extend ~40 km vertically above the general downdip trend, with a 20 km quiet gap between them at ~100 km depth. The earthquakes in the general downdip seismic zone have downdip compressional axes, while earthquakes close to the quiet gap and in the concentrated groups have an oblique component. The general decrease in slab dip angle to the north may be caused by mantle flow through the Caldas tear. The seismicity gap in the slab may be associated with an active deformation zone and the concentrated groups of earthquakes with oblique focal mechanisms could be due to a slab fold.

  9. New Frontiers in Characterization of Sub-Catalog Microseismicity: Utilizing Inter-Event Waveform Cross Correlation for Estimating Precise Locations, Magnitudes, and Focal Mechanisms of Tiny Earthquakes

    Science.gov (United States)

    Ellsworth, W. L.; Shelly, D. R.; Hardebeck, J.; Hill, D. P.

    2017-12-01

    Microseismicity often conveys the most direct information about active processes in the earth's subsurface. However, routine network processing typically leaves most earthquakes uncharacterized. These "sub-catalog" events can provide critical clues to ongoing processes in the source region. To address this issue, we have developed waveform-based processing that leverages the existing routine catalog of earthquakes to detect and characterize "sub-catalog" events (those absent in routine catalogs). By correlating waveforms of cataloged events with the continuous data stream, we 1) identify events with similar waveform signatures in the continuous data across multiple stations, 2) precisely measure relative time lags across these stations for both P- and S-wave time windows, and 3) estimate the relative polarity between events by the sign of the peak absolute value correlations and its height above the secondary peak. When combined, these inter-event comparisons yield robust measurements, which enable sensitive event detection, relative relocation, and relative magnitude estimation. The most recent addition, focal mechanisms derived from correlation-based relative polarities, addresses a significant shortcoming in microseismicity analyses (see Shelly et al., JGR, 2016). Depending on the application, we can characterize 2-10 times as many events as included in the initial catalog. This technique is particularly well suited for compact zones of active seismicity such as seismic swarms. Application to a 2014 swarm in Long Valley Caldera, California, illuminates complex patterns of faulting that would have otherwise remained obscured. The prevalence of such features in other environments remains an important, as yet unresolved, question.

  10. Focal adhesions and cell-matrix interactions

    DEFF Research Database (Denmark)

    Woods, A; Couchman, J R

    1988-01-01

    Focal adhesions are areas of cell surfaces where specializations of cytoskeletal, membrane and extracellular components combine to produce stable cell-matrix interactions. The morphology of these adhesions and the components identified in them are discussed together with possible mechanisms...

  11. Focal dermal hypoplasia without focal dermal hypoplasia

    NARCIS (Netherlands)

    Contreras-Capetillo, Silvina N.; Lombardi, Maria Paola; Pinto-Escalante, Doris; Hennekam, Raoul C.

    2014-01-01

    Focal dermal hypoplasia (FDH; Goltz-Gorlin syndrome) is an X-linked dominant disorder affecting mainly tissues of ectodermal and mesodermal origin. The phenotype is characterized by hypoplastic linear skin lesions, eye malformations, hair and teeth anomalies, and multiple limbs malformations. The

  12. SCARDEC: a new technique for the rapid determination of seismic moment magnitude, focal mechanism and source time functions for large earthquakes using body-wave deconvolution

    Science.gov (United States)

    Vallée, M.; Charléty, J.; Ferreira, A. M. G.; Delouis, B.; Vergoz, J.

    2011-01-01

    the source parameters retrieved using the SCARDEC method explain the observed surface waves as well as the Global CMT parameters, thus confirming the existing trade-off. For some well-instrumented earthquakes, our results are also supported by independent studies based on local geodetic or strong motion data. This study is mainly focused on moment determination. However, the SCARDEC method also informs us about the focal mechanism and source depth, and can be a starting point to study systematically the complexity of the STF.

  13. Focal mechanisms in the southern Aegean from temporary seismic networks – implications for the regional stress field and ongoing deformation processes

    Directory of Open Access Journals (Sweden)

    W. Friederich

    2014-05-01

    Full Text Available The lateral variation of the stress field in the southern Aegean plate and the subducting Hellenic slab is determined from recordings of seismicity obtained with the CYCNET and EGELADOS networks in the years from 2002 to 2007. First motions from 7000 well-located microearthquakes were analysed to produce 540 well-constrained focal mechanisms. They were complemented by another 140 derived by waveform matching of records from larger events. Most of these earthquakes fall into 16 distinct spatial clusters distributed over the southern Aegean region. For each cluster, a stress inversion could be carried out yielding consistent estimates of the stress field and its spatial variation. At crustal levels, the stress field is generally dominated by a steeply dipping compressional principal stress direction except in places where coupling of the subducting slab and overlying plate come into play. Tensional principal stresses are generally subhorizontal. Just behind the forearc, the crust is under arc-parallel tension whereas in the volcanic areas around Kos, Columbo and Astypalea tensional and intermediate stresses are nearly degenerate. Further west and north, in the Santorini–Amorgos graben and in the area of the islands of Mykonos, Andros and Tinos, tensional stresses are significant and point around the NW–SE direction. Very similar stress fields are observed in western Turkey with the tensional axis rotated to NNE–SSW. Intermediate-depth earthquakes below 100 km in the Nisyros region indicate that the Hellenic slab experiences slab-parallel tension at these depths. The direction of tension is close to east–west and thus deviates from the local NW-oriented slab dip presumably owing to the segmentation of the slab. Beneath the Cretan sea, at shallower levels, the slab is under NW–SE compression. Tensional principal stresses in the crust exhibit very good alignment with extensional strain rate principal axes derived from GPS velocities except

  14. Focal retinal phlebitis.

    Science.gov (United States)

    Hoang, Quan V; Freund, K Bailey; Klancnik, James M; Sorenson, John A; Cunningham, Emmett T; Yannuzzi, Lawrence A

    2012-01-01

    To report three cases of solitary, focal retinal phlebitis. An observational case series. Three eyes in three patients were noted to have unilateral decreased vision, macular edema, and a focal retinal phlebitis, which was not at an arteriovenous crossing. All three patients developed a branch retinal vein occlusion at the site of inflammation. These patients had no other evidence of intraocular inflammation, including vitritis, retinitis, retinal vasculitis, or choroiditis, nor was there any systemic disorder associated with inflammation, infection, or coagulation identified. Focal retinal phlebitis appears to be an uncommon and unique entity that produces macular edema and ultimately branch retinal vein occlusion. In our patients, the focal phlebitis and venous occlusion did not occur at an arteriovenous crossing, which is the typical site for branch retinal venous occlusive disease. This suggests that our cases represent a distinct clinical entity, which starts with a focal abnormality in the wall of a retinal venule, resulting in surrounding exudation and, ultimately, ends with branch retinal vein occlusion.

  15. Recurrent Bilateral Focal Myositis.

    Science.gov (United States)

    Nagafuchi, Hiroko; Nakano, Hiromasa; Ooka, Seido; Takakuwa, Yukiko; Yamada, Hidehiro; Tadokoro, Mamoru; Shimojo, Sadatomo; Ozaki, Shoichi

    This report describes a rare case of recurrent bilateral focal myositis and its successful treatment via methotrexate. A 38-year-old man presented myalgia of the right gastrocnemius in May 2005. Magnetic resonance imaging showed very high signal intensity in the right gastrocnemius on short-tau inversion recovery images. A muscle biopsy revealed inflammatory CD4+ cell-dominant myogenic change. Focal myositis was diagnosed. The first steroid treatment was effective. Tapering of prednisolone, however, repeatedly induced myositis relapse, which progressed to multiple muscle lesions of both lower limbs. Initiation of methotrexate finally allowed successful tapering of prednisolone, with no relapse in the past 4 years.

  16. Experimental Focal Cerebral Ischemia

    DEFF Research Database (Denmark)

    Christensen, Thomas

    2007-01-01

    Focal cerebral ischemia due to occlusion of a major cerebral artery is the cause of ischemic stroke which is a major reason of mortality, morbidity and disability in the populations of the developed countries. In the seven studies summarized in the thesis focal ischemia in rats induced by occlusion...... in the penumbra is recruited in the infarction process leading to a progressive growth of the infarct. The penumbra hence constitutes an important target for pharmacological treatment because of the existence of a therapeutic time window during which treatment with neuroprotective compounds may prevent...

  17. Recent state of stress change in the Walker Lane zone, western Basin and Range province, United States

    Science.gov (United States)

    Bellier, Olivier; Zoback, Mary Lou

    1995-06-01

    The NW to north-trending Walker Lane zone (WLZ) is located along the western boundary of the northern Basin and Range province with the Sierra Nevada. This zone is distinguished from the surrounding Basin and Range province on the basis of irregular topography and evidence for both normal and strike-slip Holocene faulting. Inversion of slip vectors from active faults, historic fault offsets, and earthquake focal mechanisms indicate two distinct Quaternary stress regimes within the WLZ, both of which are characterized by a consistent WNW σ3 axis; these are a normal faulting regime with a mean σ3 axis of N85°±9°W and a mean stress ratio (R value) (R=(σ2-σ1)/(σ3-σ1)) of 0.63-0.74 and a younger strike-slip faulting regime with a similar mean σ3 axis (N65° - 70°W) and R values ranging between ˜ 0.1 and 0.2. This younger regime is compatible with historic fault offsets and earthquake focal mechanisms. Both the extensional and strike-slip stress regimes reactivated inherited Mesozoic and Cenozoic structures and also produced new faults. The present-day strike-slip stress regime has produced strike-slip, normal oblique-slip, and normal dip-slip historic faulting. Previous workers have explained the complex interaction of active strike-slip, oblique, and normal faulting in the WLZ as a simple consequence of a single stress state with a consistent WNW σ3 axis and transitional between strike-slip and normal faulting (maximum horizontal stress approximately equal to vertical stress, or R ≈ 0 in both regimes) with minor local fluctuations. The slip data reported here support previous results from Owens Valley that suggest deformation within temporally distinct normal and strike-slip faulting stress regimes with a roughly constant WNW trending σ3 axis (Zoback, 1989). A recent change from a normal faulting to a strike-slip faulting stress regime is indicated by the crosscutting striae on faults in basalts the dominantly strike-slip earthquake focal mechanisms and

  18. Alleviation of glutamate mediated neuronal insult by piroxicam in rodent model of focal cerebral ischemia: a possible mechanism of GABA agonism.

    Science.gov (United States)

    Bhattacharya, Pallab; Pandey, Anand Kumar; Paul, Sudip; Patnaik, Ranjana

    2014-12-01

    Neurotransmitter imbalance is an inevitable outcome in cerebral ischemia that leads to neuronal death. In the present study, we evaluated the effects of piroxicam, a nonsteroidal anti-inflammatory drug (NSAID), on extracellular brain glutamate and γ-aminobutyric acid (GABA) release, survival time, and neuronal cell death. Transient focal cerebral ischemia in male Charles Foster rat led to neuronal infarction and compromised intrinsic antioxidant status. Thirty-minute preadministration of piroxicam (10 mg/kg b.w.) showed a significant (P piroxicam administration in stroke rat significantly reduced (P piroxicam attenuates extracellular glutamate release and also reduces neuronal cell death due to reduction in oxidative stress in cerebral ischemia. Our results also indicate a consequent increase of extracellular GABA in brain regions administered with piroxicam, which hints that piroxicam alleviates glutamate excitotoxicity possibly by GABA agonism.

  19. Neuroprotection of Catalpol for Experimental Acute Focal Ischemic Stroke: Preclinical Evidence and Possible Mechanisms of Antioxidation, Anti-Inflammation, and Antiapoptosis

    Directory of Open Access Journals (Sweden)

    Xia-wei Zheng

    2017-01-01

    Full Text Available Neuroprotection is defined as using a therapy that affects the brain tissue in the still-viable ischemic penumbra to salvage or delay the infarction. Catalpol, the main active principle of the root of Radix Rehmanniae, was reported to have pleiotropic neuroprotective effects in neurodegenerative diseases including ischemic stroke. Here, we evaluated the neuroprotective effects of catalpol in experimental acute ischemic stroke. Studies on catalpol in animal models of acute ischemic stroke were identified from 6 databases. Twenty-five studies involving 805 animals were included. Twelve comparisons showed significant effects of catalpol on decreasing infarct size according to 2,3,5-triphenyltetrazolium chloride staining compared with the control (P<0.05. One study reported significant effect of catalpol on reducing infarct size according to magnetic resonance imaging scan compared with the control (P<0.05. Meta-analysis of these studies indicated that catalpol significantly improved the neurological function score according to Zea Longa score, Bederson score, balance beam-walking test, adhesive removal test, bar-grasping score, and corner test compared with the control (P<0.05. In conclusion, catalpol exerted neuroprotective effects for experimental acute focal ischemic stroke, largely through reducing oxidative reactions, inhibiting apoptosis, and repressing inflammatory reactions and autophagy. However, these apparently positive findings should be interpreted with caution because of the methodological flaws.

  20. Focal myositis: A review.

    Science.gov (United States)

    Devic, P; Gallay, L; Streichenberger, N; Petiot, P

    2016-11-01

    Amongst the heterogeneous group of inflammatory myopathies, focal myositis stands as a rare and benign dysimmune disease. Although it can be associated with root and/or nerve lesions, traumatic muscle lesions and autoimmune diseases, its triggering factors remain poorly understood. Defined as an isolated inflammatory pseudotumour usually restricted to one skeletal muscle, clinical presentation of focal myositis is that of a rapidly growing solitary mass within a single muscle, usually in the lower limbs. Electromyography shows spontaneous activity associated with a myopathic pattern. MRI reveals a contrast enhanced enlarged muscle appearing hyper-intense on FAT-SAT T2 weighted images. Adjacent structures are spared and there are no calcifications. Serum creatine kinase (CK) levels are usually moderately augmented and biological markers of systemic inflammation are absent in most cases. Pathological histological features include marked variation in fibre size, inflammatory infiltrates mostly composed of T CD4+ lymphocytes and macrophages, degenerating/regenerating fibres and interstitial fibrosis. Differential diagnoses are numerous and include myositis of other origin with focal onset. Steroid treatment should be reserved for patients who present with major pain, nerve lesions, associated autoimmune disease, or elevated C reactive protein or CK. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Tiechanshan-Tunghsiao anticline earthquake analysis: Implications for northwestern Taiwan potential carbon dioxide storage site seismic hazard

    Directory of Open Access Journals (Sweden)

    Ruey-Juin Rau

    2017-01-01

    Full Text Available We analyze the seismicity and earthquake focal mechanisms beneath the Tiechanshan-Tunghsiao (TCS-TH anticline over the last two decades for seismic hazard evaluation of a potential carbon dioxide storage site in northwestern Taiwan. Seismicity in the TCS-TH anticline indicates both spatial and temporal clustering at a depth range of 7 - 12 km. Thirteen 3.0 ≤ ML ≤ 5.2 earthquake focal mechanisms show a combination of thrust, strike-slip, and normal faulting mechanisms under the TCS-TH anticline. A 1992 ML 5.2 earthquake with a focal depth of ~10 km, the largest event ever recorded beneath the TCS-TH anticline during the last two decades, has a normal fault mechanism with the T-axis trending NNE-SSW and nodal planes oriented NNW-SSE, dipping either gently to the NNE or steeply to the SSW. Thrust fault mechanisms that occurred with mostly E-W or NWW-SEE striking P-axes and strike-slip faulting events indicate NWW-SEE striking P-axes and NNE-SSW trending T-axes, which are consistent with the regional plate convergence direction. For the strike-slip faulting events, if we take the N-S or NNW-SSE striking nodal planes as the fault planes, the strike-slip faults are sinistral motions and correspond to the Tapingting fault, which is a strike-slip fault reactivated from the inherited normal fault and intersects the Tiechanshan and Tunghsiao anticlines.

  2. Pathogenesis of Focal Segmental Glomerulosclerosis

    Directory of Open Access Journals (Sweden)

    Beom Jin Lim

    2016-11-01

    Full Text Available Focal segmental glomerulosclerosis (FSGS is characterized by focal and segmental obliteration of glomerular capillary tufts with increased matrix. FSGS is classified as collapsing, tip, cellular, perihilar and not otherwise specified variants according to the location and character of the sclerotic lesion. Primary or idiopathic FSGS is considered to be related to podocyte injury, and the pathogenesis of podocyte injury has been actively investigated. Several circulating factors affecting podocyte permeability barrier have been proposed, but not proven to cause FSGS. FSGS may also be caused by genetic alterations. These genes are mainly those regulating slit diaphragm structure, actin cytoskeleton of podocytes, and foot process structure. The mode of inheritance and age of onset are different according to the gene involved. Recently, the role of parietal epithelial cells (PECs has been highlighted. Podocytes and PECs have common mesenchymal progenitors, therefore, PECs could be a source of podocyte repopulation after podocyte injury. Activated PECs migrate along adhesion to the glomerular tuft and may also contribute to the progression of sclerosis. Markers of activated PECs, including CD44, could be used to distinguish FSGS from minimal change disease. The pathogenesis of FSGS is very complex; however, understanding basic mechanisms of podocyte injury is important not only for basic research, but also for daily diagnostic pathology practice.

  3. Interactions between strike-slip earthquakes and the subduction interface near the Mendocino Triple Junction

    Science.gov (United States)

    Gong, Jianhua; McGuire, Jeffrey J.

    2018-01-01

    The interactions between the North American, Pacific, and Gorda plates at the Mendocino Triple Junction (MTJ) create one of the most seismically active regions in North America. The earthquakes rupture all three plate boundaries but also include considerable intraplate seismicity reflecting the strong internal deformation of the Gorda plate. Understanding the stress levels that drive these ruptures and estimating the locking state of the subduction interface are especially important topics for regional earthquake hazard assessment. However owing to the lack of offshore seismic and geodetic instruments, the rupture process of only a few large earthquakes near the MTJ have been studied in detail and the locking state of the subduction interface is not well constrained. In this paper, first, we use the second moments inversion method to study the rupture process of the January 28, 2015 Mw 5.7 earthquake on the Mendocino transform fault that was unusually well recorded by both onshore and offshore strong motion instruments. We estimate the rupture dimension to be approximately 6 km by 3 km corresponding to a stress drop of ∼4 MPa for a crack model. Next we investigate the frictional state of the subduction interface by simulating the afterslip that would be expected there as a result of the stress changes from the 2015 earthquake and a 2010 Mw 6.5 intraplate earthquake within the subducted Gorda plate. We simulate afterslip scenarios for a range of depths of the downdip end of the locked zone defined as the transition to velocity strengthening friction and calculate the corresponding surface deformation expected at onshore GPS monuments. We can rule out a very shallow downdip limit owing to the lack of a detectable signal at onshore GPS stations following the 2010 earthquake. Our simulations indicate that the locking depth on the slab surface is at least 14 km, which suggests that the next M8 earthquake rupture will likely reach the coastline and strong shaking should be expected there.

  4. E-W strike slip shearing of Kinwat Granitoid at South East Deccan ...

    Indian Academy of Sciences (India)

    53

    Environmental Science Trans. Royal Soc. Edin. ... Hydrogeology of Deccan Traps and associated formations in Penninsular India. Geol. Soc. ... India: constraints from geochronology, Nd–Sr isotopes and whole rock geochemistry. Precamb.

  5. E–W strike slip shearing of Kinwat granitoid at South East Deccan ...

    Indian Academy of Sciences (India)

    R D Kaplay

    2017-07-21

    Jul 21, 2017 ... Roy S and Rao R U M 1999 Geothermal investigations in the. 1993 Latur earthquake area, Deccan Volcanic Province,. India; Tectonophys. 306 237–252. Sangode S J, Mesharm D C, Kulkarni Y R, Gudadhe. S S, Malpe D B and Herlekar M A 2013 Neotectonic response of the Godavari and Kaddam Rivers ...

  6. Pseudodynamic Source Characterization for Strike-Slip Faulting Including Stress Heterogeneity and Super-Shear Ruptures

    KAUST Repository

    Mena, B.

    2012-08-08

    Reliable ground‐motion prediction for future earthquakes depends on the ability to simulate realistic earthquake source models. Though dynamic rupture calculations have recently become more popular, they are still computationally demanding. An alternative is to invoke the framework of pseudodynamic (PD) source characterizations that use simple relationships between kinematic and dynamic source parameters to build physically self‐consistent kinematic models. Based on the PD approach of Guatteri et al. (2004), we propose new relationships for PD models for moderate‐to‐large strike‐slip earthquakes that include local supershear rupture speed due to stress heterogeneities. We conduct dynamic rupture simulations using stochastic initial stress distributions to generate a suite of source models in the magnitude Mw 6–8. This set of models shows that local supershear rupture speed prevails for all earthquake sizes, and that the local rise‐time distribution is not controlled by the overall fault geometry, but rather by local stress changes on the faults. Based on these findings, we derive a new set of relations for the proposed PD source characterization that accounts for earthquake size, buried and surface ruptures, and includes local rise‐time variations and supershear rupture speed. By applying the proposed PD source characterization to several well‐recorded past earthquakes, we verify that significant improvements in fitting synthetic ground motion to observed ones is achieved when comparing our new approach with the model of Guatteri et al. (2004). The proposed PD methodology can be implemented into ground‐motion simulation tools for more physically reliable prediction of shaking in future earthquakes.

  7. Magmatic control along a strike-slip volcanic arc: The central Aeolian arc (Italy)

    KAUST Repository

    Ruch, Joel; Vezzoli, L.; De Rosa, R.; Di Lorenzo, R.; Acocella, V

    2016-01-01

    -slip motion; consistent with an E-W extension direction, with minor dextral and sinistral shear. Our data highlight six eruptive periods during the last 55 ka, which allow considering both islands as a single magmatic system, in which tectonic and magmatic

  8. Lithosphere evolution during the pre devonian of Uruguay: Prevalence of strike slip faults

    International Nuclear Information System (INIS)

    Bossi, J.

    2010-01-01

    The available data about mega shear zones were analyzed. Also the geo chronological trusty data about pre devonian rocks from Uruguay were overlapped. Emphasizing in the basic rocks, four tecto no-stratigraphy c terranes might be recognized. The approximate age of those rocks is known as well as the displacement trend. It can be concluded that the transmazonian age Piedra Alta Terrane (transmazonian age 2000 ± 100 My) is the most ancient block followed by the Tandilla Terrane (ages 2200 ± 100 My) which was joined through 1700 Ma. The Nico Perez Terrane displaced itself towards South generating the continental N10W mega shear fault Sarandi del Yi- Piriapolis towards 1250 My. Finally, the Arachania called continent made tangential collision from SE towards 525 Ma generating the ultramylonites band of the Sierra Ballena share zone. Each one of these terranes have totally different stratigraphy and lithological associations, and the chronological ages did not agree with the arrival of each one of the identified terranes

  9. Pseudodynamic Source Characterization for Strike-Slip Faulting Including Stress Heterogeneity and Super-Shear Ruptures

    KAUST Repository

    Mena, B.; Dalguer, L. A.; Mai, Paul Martin

    2012-01-01

    . (2004), we propose new relationships for PD models for moderate‐to‐large strike‐slip earthquakes that include local supershear rupture speed due to stress heterogeneities. We conduct dynamic rupture simulations using stochastic initial stress

  10. High Frequency Near-Field Ground Motion Excited by Strike-Slip Step Overs

    Science.gov (United States)

    Hu, Feng; Wen, Jian; Chen, Xiaofei

    2018-03-01

    We performed dynamic rupture simulations on step overs with 1-2 km step widths and present their corresponding horizontal peak ground velocity distributions in the near field within different frequency ranges. The rupture speeds on fault segments are determinant in controlling the near-field ground motion. A Mach wave impact area at the free surface, which can be inferred from the distribution of the ratio of the maximum fault-strike particle velocity to the maximum fault-normal particle velocity, is generated in the near field with sustained supershear ruptures on fault segments, and the Mach wave impact area cannot be detected with unsustained supershear ruptures alone. Sub-Rayleigh ruptures produce stronger ground motions beyond the end of fault segments. The existence of a low-velocity layer close to the free surface generates large amounts of high-frequency seismic radiation at step over discontinuities. For near-vertical step overs, normal stress perturbations on the primary fault caused by dipping structures affect the rupture speed transition, which further determines the distribution of the near-field ground motion. The presence of an extensional linking fault enhances the near-field ground motion in the extensional regime. This work helps us understand the characteristics of high-frequency seismic radiation in the vicinities of step overs and provides useful insights for interpreting the rupture speed distributions derived from the characteristics of near-field ground motion.

  11. Seismicity and seismogenic structures of Central Apennines (Italy): constraints on the present-day stress field from focal mechanisms - The SLAM (Seismicity of Lazio-Abruzzo and Molise) project

    Science.gov (United States)

    Frepoli, Alberto; Battista Cimini, Giovanni; De Gori, Pasquale; De Luca, Gaetano; Marchetti, Alessandro; Montuori, Caterina; Pagliuca, Nicola

    2016-04-01

    We present new results for the microseismic activity in the Central Apennines recorded from a total of 81seismic stations. The large number of recording sites derives from the combination of temporary and permanent seismic networks operating in the study region. Between January 2009 and October 2013 we recorded 6923 earthquakes with local magnitudes ML ranging from 0.1 to 4.8. We located hypocentres by using a refined 1D crustal velocity model. The majority of the hypocenters are located beneath the axes of the Apenninic chain, while the seismic activity observed along the peri-Tyrrhenian margin is lower. The seismicity extends to a depth of 32 km; the hypocentral depth distribution exhibits a pronounced peak of seismic energy release in the depth range between 8 and 20 km. During the observation period we recorded two major seismic swarms and one seismic sequence in the Marsica-Sorano area in which we have had the largest detected magnitude (ML = 4.8). Fault plane solutions for a total of 600 earthquakes were derived from P-polarities. This new data set consists of a number of focal plane solutions that is about four times the data so far available for regional stress field study. The majority of the focal mechanisms show predominantly normal fault solutions. T-axis trends are oriented NE-SW confirming that the area is in extension. We also derived the azimuths of the principal stress axes by inverting the fault plane solutions and calculated the direction of the maximum horizontal stress, which is mainly sub-vertical oriented. The study region has been historically affected by many strong earthquakes, some of them very destructive. This work can give an important contribution to the seismic hazard assessment in an area densely populated as the city of Rome which is distant around 60 km from the main seismogenic structures of Central Apennine.

  12. Focal femoral condyle resurfacing.

    LENUS (Irish Health Repository)

    Brennan, S A

    2013-03-01

    Focal femoral inlay resurfacing has been developed for the treatment of full-thickness chondral defects of the knee. This technique involves implanting a defect-sized metallic or ceramic cap that is anchored to the subchondral bone through a screw or pin. The use of these experimental caps has been advocated in middle-aged patients who have failed non-operative methods or biological repair techniques and are deemed unsuitable for conventional arthroplasty because of their age. This paper outlines the implant design, surgical technique and biomechanical principles underlying their use. Outcomes following implantation in both animal and human studies are also reviewed. Cite this article: Bone Joint J 2013;95-B:301-4.

  13. Systemic focal epileptogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Remler, M.P.; Marcussen, W.H.

    1986-01-01

    Rats that receive radiation to 0.25 cc of one cerebral hemisphere are clinically and electroencephalographically normal until there is a breakdown of the blood-brain barrier (BBB) at 3 to 6 months postradiation. This BBB lesion can be detected by transient focal seizure activity produced by the BBB-excluded systemic convulsant bicuculline methiodide. In two rats the seizure activity induced by this one injection was self-sustaining. In seven of 15 other rats tested, the subsequent administration of repeated 2 mg/kg injections created a chronic focus that continued to spike with great frequency for 3 weeks or more without further administration of any convulsant. In three of eight other rats, implanted minipumps delivering 180 micrograms/h of bicuculline methiodide produced self-sustaining epileptic activity.

  14. Recombinant Tissue Plasminogen Activator Induces Neurological Side Effects Independent on Thrombolysis in Mechanical Animal Models of Focal Cerebral Infarction: A Systematic Review and Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Mei-Xue Dong

    Full Text Available Recombinant tissue plasminogen activator (rtPA is the only effective drug approved by US FDA to treat ischemic stroke, and it contains pleiotropic effects besides thrombolysis. We performed a meta-analysis to clarify effect of tissue plasminogen activator (tPA on cerebral infarction besides its thrombolysis property in mechanical animal stroke.Relevant studies were identified by two reviewers after searching online databases, including Pubmed, Embase, and ScienceDirect, from 1979 to 2016. We identified 6, 65, 17, 12, 16, 12 and 13 comparisons reporting effect of endogenous tPA on infarction volume and effects of rtPA on infarction volume, blood-brain barrier, brain edema, intracerebral hemorrhage, neurological function and mortality rate in all 47 included studies. Standardized mean differences for continuous measures and risk ratio for dichotomous measures were calculated to assess the effects of endogenous tPA and rtPA on cerebral infarction in animals. The quality of included studies was assessed using the Stroke Therapy Academic Industry Roundtable score. Subgroup analysis, meta-regression and sensitivity analysis were performed to explore sources of heterogeneity. Funnel plot, Trim and Fill method and Egger's test were obtained to detect publication bias.We found that both endogenous tPA and rtPA had not enlarged infarction volume, or deteriorated neurological function. However, rtPA would disrupt blood-brain barrier, aggravate brain edema, induce intracerebral hemorrhage and increase mortality rate.This meta-analysis reveals rtPA can lead to neurological side effects besides thrombolysis in mechanical animal stroke, which may account for clinical exacerbation for stroke patients that do not achieve vascular recanalization with rtPA.

  15. Focal midbrain tumors in children

    NARCIS (Netherlands)

    Vandertop, W. P.; Hoffman, H. J.; Drake, J. M.; Humphreys, R. P.; Rutka, J. T.; Amstrong, D. C.; Becker, L. E.

    1992-01-01

    The clinical and neuroradiological features of focal midbrain tumors in 12 children are described, and the results of their surgical management are presented. Patients with a focal midbrain tumor usually exhibit either symptoms and signs of raised intracranial pressure caused by an obstructive

  16. Focal Mechanism of a Catastrophic Earthquake of the Last Rococo Period (1783) in Southern Italy Retrieved by Inverting Historical Information on Damage

    Science.gov (United States)

    Sirovich, L.; Pettenati, F.

    2007-05-01

    Using geophysical inversion to discover the fault source of a blind earthquake, that took place before the invention of the seismograph, seemed impossible. We demonstrated that sometimes it is possible using our simplified KF model (Sirovich, 1996) through automatic genetic inversion (Gentile et al., 2004 in BSSA; Sirovich and Pettenati, 2004 in JGR), and determined it conclusively by treating the Coalinga 1983, Loma Prieta 1989, and Northridge 1994 earthquakes (Pettenati and Sirovich, 2007 in BSSA). KF is able to simulate the body-wave radiation from a linear source, and eleven source parameters are retrieved: the three nucleation coordinates, the fault-plane solution, the seismic moment, the rupture velocities and lengths along-strike and anti-strike, the shear wave velocity in the half-space. To find the minima on the hypersurface of the residuals in the multi-parameter model space, we use a genetic process with niching since we have already shown that the problem is bimodal for pure dip-slip mechanisms. The objective function of the nonlinear inversion is the sum of the squared residuals (calculated-minus-observed intensity at all sites). Here, we use the very good intensity data provided in the MCS scale by the INGV of Italy for the M 6.9 earthquake of Feb. 5, 1783 (see the Italian intensity data bank on http:emidius.mi.ingv.it/DOM/consultazione.html). The data of 1783 were created by seismologists and historians who interpreted the reports of the time and many other historical sources. Given the limitations of the KF approach, we limited our inversion to a square area of 200 by 200 km around the most heavily damaged zone. 341 surveyed towns and hamlets received intensity degrees by INGV (we discarded 6 of them as statistical outliers according to the classical Chauvenet method). Thus, 335 data were inverted. The match between experimental and synthetic isoseismals is really noteworthy. The found mechanism is almost pure dip-slip and, thus, the problem is

  17. Båth's law and its relation to the tectonic environment: A case study for earthquakes in Mexico

    Science.gov (United States)

    Rodríguez-Pérez, Q.; Zúñiga, F. R.

    2016-09-01

    We studied 66 mainshocks and their largest aftershocks in the Mexican subduction zone and in the Gulf of California with magnitudes in the range of 5.2 worldwide studies supporting the observation of mechanism dependence of radiated seismic energy. The statistical tests indicate that the only significant difference is for shallow thrust and strike-slip events for these parameters. The statistical comparison of stress drop of shallow thrust versus that of inslab events shows a strongly significant difference with a confidence better than 99%. The comparison of stress drop of shallow thrust events with that of strike-slip events, also indicates a strongly significant difference. We see no dependence of stress drop with magnitude, which is strong evidence of earthquake self-similarity. We do not observe a systematic depth dependence of stress drop. The results also reveal differences in the earthquake rupture among the events. The magnitude difference between the mainshock and the largest aftershock for inslab events is larger than interplate and strike-slip events suggesting focal mechanism dependence of Båth's law. For the case of this parameter, only that for inslab and strike-slip events present a significant difference with 95% confidence.

  18. Using focal mechanism solutions to correlate earthquakes with faults in the Lake Tahoe-Truckee area, California and Nevada, and to help design LiDAR surveys for active-fault reconnaissance

    Science.gov (United States)

    Cronin, V. S.; Lindsay, R. D.

    2011-12-01

    Geomorphic analysis of hillshade images produced from aerial LiDAR data has been successful in identifying youthful fault traces. For example, the recently discovered Polaris fault just northwest of Lake Tahoe, California/Nevada, was recognized using LiDAR data that had been acquired by local government to assist land-use planning. Subsequent trenching by consultants under contract to the US Army Corps of Engineers has demonstrated Holocene displacement. The Polaris fault is inferred to be capable of generating a magnitude 6.4-6.9 earthquake, based on its apparent length and offset characteristics (Hunter and others, 2011, BSSA 101[3], 1162-1181). Dingler and others (2009, GSA Bull 121[7/8], 1089-1107) describe paleoseismic or geomorphic evidence for late Neogene displacement along other faults in the area, including the West Tahoe-Dollar Point, Stateline-North Tahoe, and Incline Village faults. We have used the seismo-lineament analysis method (SLAM; Cronin and others, 2008, Env Eng Geol 14[3], 199-219) to establish a tentative spatial correlation between each of the previously mentioned faults, as well as with segments of the Dog Valley fault system, and one or more earthquake(s). The ~18 earthquakes we have tentatively correlated with faults in the Tahoe-Truckee area occurred between 1966 and 2008, with magnitudes between 3 and ~6. Given the focal mechanism solution for a well-located shallow-focus earthquake, the nodal planes can be projected to Earth's surface as represented by a DEM, plus-or-minus the vertical and horizontal uncertainty in the focal location, to yield two seismo-lineament swaths. The trace of the fault that generated the earthquake is likely to be found within one of the two swaths [1] if the fault surface is emergent, and [2] if the fault surface is approximately planar in the vicinity of the focus. Seismo-lineaments from several of the earthquakes studied overlap in a manner that suggests they are associated with the same fault. The surface

  19. Seismotectonics and fault structure of the California Central Coast

    Science.gov (United States)

    Hardebeck, Jeanne L.

    2010-01-01

    I present and interpret new earthquake relocations and focal mechanisms for the California Central Coast. The relocations improve upon catalog locations by using 3D seismic velocity models to account for lateral variations in structure and by using relative arrival times from waveform cross-correlation and double-difference methods to image seismicity features more sharply. Focal mechanisms are computed using ray tracing in the 3D velocity models. Seismicity alignments on the Hosgri fault confirm that it is vertical down to at least 12 km depth, and the focal mechanisms are consistent with right-lateral strike-slip motion on a vertical fault. A prominent, newly observed feature is an ~25 km long linear trend of seismicity running just offshore and parallel to the coastline in the region of Point Buchon, informally named the Shoreline fault. This seismicity trend is accompanied by a linear magnetic anomaly, and both the seismicity and the magnetic anomaly end where they obliquely meet the Hosgri fault. Focal mechanisms indicate that the Shoreline fault is a vertical strike-slip fault. Several seismicity lineations with vertical strike-slip mechanisms are observed in Estero Bay. Events greater than about 10 km depth in Estero Bay, however, exhibit reverse-faulting mechanisms, perhaps reflecting slip at the top of the remnant subducted slab. Strike-slip mechanisms are observed offshore along the Hosgri–San Simeon fault system and onshore along the West Huasna and Rinconada faults, while reverse mechanisms are generally confined to the region between these two systems. This suggests a model in which the reverse faulting is primarily due to restraining left-transfer of right-lateral slip.

  20. Analysis and Simulation of 3D Scattering due to Heterogeneous Crustal Structure and Surface Topography on Regional Phases; Magnitude and Discrimination

    Science.gov (United States)

    2009-07-07

    inversion technique that is based on different weights for relatively high frequency waveform modeling of Pnl and relatively long period surface waves (Tan...et al., 2006). Pnl and surface waves are also allowed to shift in time to take into account of uncertainties in velocity structure. Joint...inversion of Pnl and surface waves provides better constraints on focal depth as well as source mechanisms. The pure strike-slip mechanism of the earthquake

  1. Source mechanisms of persistent shallow earthquakes during eruptive and non-eruptive periods between 1981 and 2011 at Mount St. Helens, Washington

    Science.gov (United States)

    Lehto, Heather L.; Roman, Diana C.; Moran, Seth C.

    2013-01-01

    Shallow seismicity between 0 and 3-km depth has persisted at Mount St. Helens, Washington (MSH) during both eruptive and non-eruptive periods for at least the past thirty years. In this study we investigate the source mechanisms of shallow volcano-tectonic (VT) earthquakes at MSH by calculating high-quality hypocenter locations and fault plane solutions (FPS) for all VT events recorded during two eruptive periods (1981–1986 and 2004–2008) and two non-eruptive periods (1987–2004 and 2008–2011). FPS show a mixture of normal, reverse, and strike-slip faulting during all periods, with a sharp increase in strike-slip faulting observed in 1987–1997 and an increase in normal faulting in 1998–2004. FPS P-axis orientations show a ~ 90° rotation with respect to regional σ1 (N23°E) during 1981–1986 and 2004–2008, bimodal orientations (~ N-S and ~ E-W) during 1987–2004, and bimodal orientations at ~ N-E and ~ S-W from 2008–2011. We interpret these orientations to likely be due to pressurization accompanying the shallow intrusion and subsequent eruption of magma as domes during 1981–1986 and 2004–2008 and the buildup of pore pressure beneath a seismogenic volume (located at 0–1 km) with a smaller component due to the buildup of tectonic forces during 1987–2004 and 2008–2011.

  2. Diagnostic imaging in focal epilepsy

    International Nuclear Information System (INIS)

    Zlatareva, D.

    2013-01-01

    Focal epilepsies account for 60% of all seizure disorders worldwide. In this review the classic and new classification system of epileptic seizures and syndromes as well as genetic forms are discussed. Magnetic resonance (MR) is the technique of choice for diagnostic imaging in focal epilepsy because of its sensitivity and high tissue contrast. The review is focused on the lack of consensus of imaging protocols and reported findings in refractory epilepsy. The most frequently encountered MRI findings in epilepsy are reported and their imaging characteristics are depicted. Diagnosis of hippocampal sclerosis and malformations of cortical development as two major causes of refractory focal epilepsy is described in details. Some promising new techniques as positron emission tomography computed tomography (PET/CT) and MR and PET/CT fusion are briefly discussed. Also the relevance of adequate imaging in focal epilepsy, some practical points in imaging interpretation and differential diagnosis are highlighted. (author)

  3. The 1987 Whittier Narrows, California, earthquake: A Metropolitan shock

    OpenAIRE

    Hauksson, Egill; Stein, Ross S.

    1989-01-01

    Just 3 hours after the Whittier Narrows earthquake struck, it became clear that a heretofore unseen geological structure was seismically active beneath metropolitan Los Angeles. Contrary to initial expectations of strike-slip or oblique-slip motion on the Whittier fault, whose north end abuts the aftershock zone, the focal mechanism of the mainshock showed pure thrust faulting on a deep gently inclined surface [Hauksson et al., 1988]. This collection of nine research reports spans the spectru...

  4. Thermomechanical architecture of the VIS focal plane for Euclid

    International Nuclear Information System (INIS)

    Martignac, Jerome; Carty, Michael; Tourette, Thierry; Bachet, Damien; Berthe, Michel; Augueres, Jean-Louis; Amiaux, Jerome; Fontignie, Jean; Horeau, Benoit; Renaud, Diana

    2014-01-01

    One of the main challenges for current and near future space experiments is the increase of focal plane complexity in terms of amount of pixels. In the frame work of the ESA Euclid mission to be launched in 2020, the Euclid Consortium is developing an extremely large and stable focal plane for the VIS instrument. CEA has developed the thermomechanical architecture of that Focal Plane taking into account all the very stringent performance and mission related requirements. The VIS Focal Plane Assembly integrates 36 CCDs (operated at 150 K) connected to their front end electronics (operated at 280 K) as to obtain one of the largest focal plane (0.6 billion pixels) ever built for space application after the GAIA one. The CCDs are CCD273 type specially designed and provided by the e2v company under ESA contract, front end electronics is studied and provided by MSSL. In this paper we first recall the specific requirements that have driven the overall architecture of the VIS-FPA and especially the solutions proposed to cope with the scientific needs of an extremely stable focal plane, both mechanically and thermally. The mechanical structure based on SiC material used for the cold sub assembly supporting the CCDs is detailed. We describe also the modular architecture concept that we have selected taking into account AIT-AIV and programmatic constraints. (authors)

  5. Continuously variable focal length lens

    Science.gov (United States)

    Adams, Bernhard W; Chollet, Matthieu C

    2013-12-17

    A material preferably in crystal form having a low atomic number such as beryllium (Z=4) provides for the focusing of x-rays in a continuously variable manner. The material is provided with plural spaced curvilinear, optically matched slots and/or recesses through which an x-ray beam is directed. The focal length of the material may be decreased or increased by increasing or decreasing, respectively, the number of slots (or recesses) through which the x-ray beam is directed, while fine tuning of the focal length is accomplished by rotation of the material so as to change the path length of the x-ray beam through the aligned cylindrical slows. X-ray analysis of a fixed point in a solid material may be performed by scanning the energy of the x-ray beam while rotating the material to maintain the beam's focal point at a fixed point in the specimen undergoing analysis.

  6. Testing of focal plane arrays

    International Nuclear Information System (INIS)

    Merriam, J.D.

    1988-01-01

    Problems associated with the testing of focal plane arrays are briefly examined with reference to the instrumentation and measurement procedures. In particular, the approach and instrumentation used as the Naval Ocean Systems Center is presented. Most of the measurements are made with flooded illumination on the focal plane array. The array is treated as an ensemble of individual pixels, data being taken on each pixel and array averages and standard deviations computed for the entire array. Data maps are generated, showing the pixel data in the proper spatial position on the array and the array statistics

  7. Focal therapy in prostate cancer

    NARCIS (Netherlands)

    van den Bos, W.

    2016-01-01

    Interesting developments took place in the treatment of prostate cancer including focal therapy for less aggressive organ-confined prostate cancer. Fortunately, curative treatment is often still an option for patients suffering from the lower staged tumors. In carefully selected patients, the

  8. Gallbladder adenoma with focal adenocarcinoma.

    Science.gov (United States)

    Ciurea, S; Matei, E; Petrisor, P; Luca, L; Boros, Mirela; Herlea, V; Popescu, I

    2008-01-01

    The majority of polypoid lesions of the gallbladder are cholesterolosis pseudopolyps. True neoplastic GB polyps are represented mainly by adenomas. The case of a 52-year old male patient with an adenomatous polyp of the GB with focal adenocarcinoma is presented.

  9. Charging as a Focal Practice

    DEFF Research Database (Denmark)

    Bødker, Mads

    This position paper reflects on Borgmann’s notion of ‘focal things’ and its applicability in the discourse about interaction with technologies in nature. Using the example of a combined cooking burner and thermoelectric 5W smartphone charger (a BioLite cook stove), this position paper gives...

  10. The Sentinel-4 UVN focal plane assemblies

    Science.gov (United States)

    Hinger, Jürgen; Hohn, Rüdiger; Gebhardt, Eyk; Reichardt, Jörg

    2017-09-01

    The Sentinel-4 UVN Instrument is a dispersive imaging spectrometer covering the UV-VIS and the NIR wavelength. It is developed and built under an ESA contract by an industrial consortium led by Airbus Defence and Space. It will be accommodated on board of the MTG-S (Meteosat Third Generation - Sounder) satellite that will be placed in a geostationary orbit over Europe sampling data for generating two-dimensional maps of a number of atmospheric trace gases. The incoming light is dispersed by reflective gratings and detected by the two (UVVIS and NIR) CCDs mounted inside the focal plane assemblies. Both CCD detectors acquire spectral channels and spatial sampling in two orthogonal directions and will be operated at about 215 K mainly to minimize random telegraph signal effects and to reduce dark current. Stringent detector temperature as well as alignment stability requirements of less than +/-0.1 K per day respectively of less than 2 micrometers/2 arcseconds from ground to orbit are driving the FPA thermo-mechanical design. A specific FPA design feature is the redundant LED-calibration system for bad pixel detection as well as pixel gain and linearity monitoring. This paper reports on the design and qualification of the Focal Plane Assemblies with emphasis on thermo-mechanical as well as alignment stability verification.

  11. [Focal myositis: An unknown disease].

    Science.gov (United States)

    Gallay, L; Streichenberger, N; Benveniste, O; Allenbach, Y

    2017-10-01

    Focal myositis are inflammatory muscle diseases of unknown origin. At the opposite from the other idiopathic inflammatory myopathies, they are restricted to a single muscle or to a muscle group. They are not associated with extramuscular manifestations, and they have a good prognosis without any treatment. They are characterized by a localized swelling affecting mostly lower limbs. The pseudo-tumor can be painful, but is not associated with a muscle weakness. Creatine kinase level is normal. Muscle MRI shows an inflammation restricted to a muscle or a muscle group. Muscle biopsy and pathological analysis remain necessary for the diagnosis, showing inflammatory infiltrates composed by macrophages and lymphocytes without any specific distribution within the muscle. Focal overexpression of HLA-1 by the muscle fibers is frequently observed. The muscle biopsy permits to rule out differential diagnosis such a malignancy (sarcoma). Spontaneous remission occurs within weeks or months after the first symptoms, relapse is unusual. Copyright © 2017. Published by Elsevier SAS.

  12. A bottom-driven mechanism for distributed faulting in the Gulf of California rift

    Science.gov (United States)

    Persaud, Patricia; Tan, Eh; Contreras, Juan; Lavier, Luc

    2017-11-01

    Observations of active faulting in the continent-ocean transition of the Northern Gulf of California show multiple oblique-slip faults distributed in a 200 × 70 km2 area developed some time after a westward relocation of the plate boundary at 2 Ma. In contrast, north and south of this broad pull-apart structure, major transform faults accommodate Pacific-North America plate motion. Here we propose that the mechanism for distributed brittle deformation results from the boundary conditions present in the Northern Gulf, where basal shear is distributed between the Cerro Prieto strike-slip fault (southernmost fault of the San Andreas fault system) and the Ballenas Transform Fault. We hypothesize that in oblique-extensional settings whether deformation is partitioned in a few dip-slip and strike-slip faults, or in numerous oblique-slip faults may depend on (1) bottom-driven, distributed extension and shear deformation of the lower crust or upper mantle, and (2) the rift obliquity. To test this idea, we explore the effects of bottom-driven shear on the deformation of a brittle elastic-plastic layer with the help of pseudo-three dimensional numerical models that include side forces. Strain localization results when the basal shear abruptly increases in a step-function manner while oblique-slip on numerous faults dominates when basal shear is distributed. We further explore how the style of faulting varies with obliquity and demonstrate that the style of delocalized faulting observed in the Northern Gulf of California is reproduced in models with an obliquity of 0.7 and distributed basal shear boundary conditions, consistent with the interpreted obliquity and boundary conditions of the study area.

  13. Focal cortical dysplasia – review

    International Nuclear Information System (INIS)

    Kabat, Joanna; Król, Przemysław

    2012-01-01

    Focal cortical dysplasia is a malformation of cortical development, which is the most common cause of medically refractory epilepsy in the pediatric population and the second/third most common etiology of medically intractable seizures in adults. Both genetic and acquired factors are involved in the pathogenesis of cortical dysplasia. Numerous classifications of the complex structural abnormalities of focal cortical dysplasia have been proposed – from Taylor et al. in 1971 to the last modification of Palmini classification made by Blumcke in 2011. In general, three types of cortical dysplasia are recognized. Type I focal cortical dysplasia with mild symptomatic expression and late onset, is more often seen in adults, with changes present in the temporal lobe. Clinical symptoms are more severe in type II of cortical dysplasia usually seen in children. In this type, more extensive changes occur outside the temporal lobe with predilection for the frontal lobes. New type III is one of the above dysplasias with associated another principal lesion as hippocampal sclerosis, tumor, vascular malformation or acquired pathology during early life. Brain MRI imaging shows abnormalities in the majority of type II dysplasias and in only some of type I cortical dysplasias. The most common findings on MRI imaging include: focal cortical thickening or thinning, areas of focal brain atrophy, blurring of the gray-white junction, increased signal on T2- and FLAIR-weighted images in the gray and subcortical white matter often tapering toward the ventricle. On the basis of the MRI findings, it is possible to differentiate between type I and type II cortical dysplasia. A complete resection of the epileptogenic zone is required for seizure-free life. MRI imaging is very helpful to identify those patients who are likely to benefit from surgical treatment in a group of patients with drug-resistant epilepsy. However, in type I cortical dysplasia, MR imaging is often normal, and also in both

  14. Axial and focal-plane diffraction catastrophe integrals

    International Nuclear Information System (INIS)

    Berry, M V; Howls, C J

    2010-01-01

    Exact expressions in terms of Bessel functions are found for some of the diffraction catastrophe integrals that decorate caustics in optics and mechanics. These are the axial and focal-plane sections of the elliptic and hyperbolic umbilic diffraction catastrophes, and symmetric elliptic and hyperbolic unfoldings of the X 9 diffraction catastrophes. These representations reveal unexpected relations between the integrals.

  15. Serial neuroradiological studies in focal cerebritis

    International Nuclear Information System (INIS)

    Hatta, S.; Mochizuki, H.; Kuru, Y.; Miwa, H.; Kondo, T.; Mori, H.; Mizuno, Y.

    1994-01-01

    We report serial neuroradiological studies in a patient with focal cerebritis in the head of the left caudate nucleus. On the day after the onset of symptoms, CT showed an ill-defined low density lesion. The lack of contrast enhancement appeared to be the most important finding for differentiating focal cerebritis from an encapsulated brain abscess or a tumour. MRI two days later revealed the centre of the lesion to be of slightly low intensity on T1-weighted inversion recovery (IR) images and very low intensity on T2-weighted spin echo images, which appeared to correspond to the early cerebritis stage of experimentally induced cerebritis and brain abscess. Ten days after the onset of symptoms, CT revealed a thin ring of enhancement in the head of the caudate nucleus, and a similar small ring was seen in the hypothalamus 16 days after the onset, corresponding to the late cerebritis stage. MRI nine days later revealed ill-defined high signal lesions within the involved area on the T1-weighted IR images. To our knowledge, this is the first published MRI documentation of the early cerebritis stage developing into an encapsulated brain abscess. The mechanisms underlying of these radiographic changes are discussed. (orig.)

  16. Structural and effective connectivity in focal epilepsy

    Directory of Open Access Journals (Sweden)

    Christopher S. Parker

    2018-01-01

    Full Text Available Patients with medically-refractory focal epilepsy may be candidates for neurosurgery and some may require placement of intracranial EEG electrodes to localise seizure onset. Assessing cerebral responses to single pulse electrical stimulation (SPES may give diagnostically useful data. SPES produces cortico-cortical evoked potentials (CCEPs, which infer effective brain connectivity. Diffusion-weighted images and tractography may be used to estimate structural brain connectivity. This combination provides the opportunity to observe seizure onset and its propagation throughout the brain, spreading contiguously along the cortex explored with electrodes, or non-contiguously. We analysed CCEPs and diffusion tractography in seven focal epilepsy patients and reconstructed the effective and structural brain networks. We aimed to assess the inter-modal similarity of the networks at a large scale across the cortex, the effective and structural connectivity of the ictal-onset zone, and investigate potential mechanisms of non-contiguous seizure spread. We found a significant overlap between structural and effective networks. Effective network CCEP amplitude, baseline variation, and outward connectivity was higher at ictal-onset zones, while structural connection strength within the ictal-onset zone tended to be higher. These findings support the concept of hyperexcitable cortex being associated with seizure generation. The high prevalence of structural and effective connections from the ictal-onset zone to sites of non-contiguous spread suggests that macroscopic structural and effective connections are plausible routes for non-contiguous seizure spread.

  17. Ultrasound elastographic techniques in focal liver lesions.

    Science.gov (United States)

    Conti, Clara Benedetta; Cavalcoli, Federica; Fraquelli, Mirella; Conte, Dario; Massironi, Sara

    2016-03-07

    Elastographic techniques are new ultrasound-based imaging techniques developed to estimate tissue deformability/stiffness. Several ultrasound elastographic approaches have been developed, such as static elastography, transient elastography and acoustic radiation force imaging methods, which include point shear wave and shear wave imaging elastography. The application of these methods in clinical practice aims at estimating the mechanical tissues properties. One of the main settings for the application of these tools has been liver stiffness assessment in chronic liver disease, which has been studied mainly using transient elastography. Another field of application for these techniques is the assessment of focal lesions, detected by ultrasound in organs such as pancreas, prostate, breast, thyroid, lymph nodes. Considering the frequency and importance of the detection of focal liver lesions through routine ultrasound, some studies have also aimed to assess the role that elestography can play in studying the stiffness of different types of liver lesions, in order to predict their nature and thus offer valuable non-invasive methods for the diagnosis of liver masses.

  18. RMT focal plane sensitivity to seismic network geometry and faulting style

    Science.gov (United States)

    Johnson, Kendra L.; Hayes, Gavin; Herrmann, Robert B.; Benz, Harley M.; McNamara, Daniel E.; Bergman, Eric A.

    2016-01-01

    by Scenario 1, with a range of 26°. We draw two main conclusions from this study. (1) Station distribution impacts our ability to constrain RMTs using waveform time-series; however, in some tectonic settings, faulting style also plays a significant role and (2) increasing station density and data quantity (both the number of stations and the number of individual channels) does not necessarily improve RMT constraint. These results may be useful when organizing future seismic deployments (e.g. by concentrating stations in alignment with anticipated nodal planes), and in computing RMTs, either by guiding a more rigorous data selection process for input data or informing variable weighting among the selected data (e.g. by eliminating the transverse component when strike-slip mechanisms are expected).

  19. Systems considerations in mosaic focal planes

    Science.gov (United States)

    White, K. P., III

    1983-08-01

    Two key reasons for pursuing the development of mosaic focal planes are reviewed and it is shown that rapid frame repetition rate is the only requirement that can be solved no other way than through mosaic focal planes. With the view that spaceborne mosaic focal plane sensors are necessarily 'smart sensors' requiring a lot of onboard processing just to function, it is pointed out that various artificial intelligence techniques may be the most appropriate to incorporate in the data processing. Finally, a novel mosaic focal plane design is proposed, termed a virtual mosaic focal plane, in response to other system constraints.

  20. TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly

    Science.gov (United States)

    Uchil, Pradeep D.; Pawliczek, Tobias; Reynolds, Tracy D.; Ding, Siyuan; Hinz, Angelika; Munro, James B.; Huang, Fang; Floyd, Robert W.; Yang, Haitao; Hamilton, William L.; Bewersdorf, Joerg; Xiong, Yong; Calderwood, David A.; Mothes, Walther

    2014-01-01

    ABSTRACT Focal adhesions are macromolecular complexes that connect the actin cytoskeleton to the extracellular matrix. Dynamic turnover of focal adhesions is crucial for cell migration. Paxillin is a multi-adaptor protein that plays an important role in regulating focal adhesion dynamics. Here, we identify TRIM15, a member of the tripartite motif protein family, as a paxillin-interacting factor and a component of focal adhesions. TRIM15 localizes to focal contacts in a myosin-II-independent manner by an interaction between its coiled-coil domain and the LD2 motif of paxillin. Unlike other focal adhesion proteins, TRIM15 is a stable focal adhesion component with restricted mobility due to its ability to form oligomers. TRIM15-depleted cells display impaired cell migration and reduced focal adhesion disassembly rates, in addition to enlarged focal adhesions. Thus, our studies demonstrate a cellular function for TRIM15 as a regulatory component of focal adhesion turnover and cell migration. PMID:25015296

  1. Heterogeneity of Focal Adhesions and Focal Contacts in Motile Fibroblasts.

    Science.gov (United States)

    Gladkikh, Aleena; Kovaleva, Anastasia; Tvorogova, Anna; Vorobjev, Ivan A

    2018-01-01

    Cell-extracellular matrix (ECM) adhesion is an important property of virtually all cells in multicellular organisms. Cell-ECM adhesion studies, therefore, are very significant both for biology and medicine. Over the last three decades, biomedical studies resulted in a tremendous advance in our understanding of the molecular basis and functions of cell-ECM adhesion. Based on morphological and molecular criteria, several different types of model cell-ECM adhesion structures including focal adhesions, focal complexes, fibrillar adhesions, podosomes, and three-dimensional matrix adhesions have been described. All the subcellular structures that mediate cell-ECM adhesion are quite heterogeneous, often varying in size, shape, distribution, dynamics, and, to a certain extent, molecular constituents. The morphological "plasticity" of cell-ECM adhesion perhaps reflects the needs of cells to sense, adapt, and respond to a variety of extracellular environments. In addition, cell type (e.g., differentiation status, oncogenic transformation, etc.) often exerts marked influence on the structure of cell-ECM adhesions. Although molecular, genetic, biochemical, and structural studies provide important maps or "snapshots" of cell-ECM adhesions, the area of research that is equally valuable is to study the heterogeneity of FA subpopulations within cells. Recently time-lapse observations on the FA dynamics become feasible, and behavior of individual FA gives additional information on cell-ECM interactions. Here we describe a robust method of labeling of FA using plasmids with fluorescent markers for paxillin and vinculin and quantifying the morphological and dynamical parameters of FA.

  2. The 11 May 2011 earthquake at Lorca (SE Spain viewed in a structural-tectonic context

    Directory of Open Access Journals (Sweden)

    R. L. M. Vissers

    2011-10-01

    Full Text Available The Lorca earthquake of 11 May 2011 in the Betic Cordillera of SE Spain occurred almost exactly on the Alhama de Murcia fault, a marked fault that forms part of a NE-SW trending belt of faults and thrusts. The fault belt is reminiscent of a strike-slip corridor, but recent structural studies have provided clear evidence for reverse motions on these faults. Focal mechanisms of the main earthquake, but also of a foreshock, are strikingly consistent with structural observations on the Alhama de Murcia fault. This strengthens the conclusion that, rather than a strike-slip fault, the fault is at present a contractional fault with an oblique reverse sense of motion, presumably in response to the NW-directed motion of Africa with respect to Europe.

  3. Interferon Induced Focal Segmental Glomerulosclerosis

    Directory of Open Access Journals (Sweden)

    Yusuf Kayar

    2016-01-01

    Full Text Available Behçet’s disease is an inflammatory disease of unknown etiology which involves recurring oral and genital aphthous ulcers and ocular lesions as well as articular, vascular, and nervous system involvement. Focal segmental glomerulosclerosis (FSGS is usually seen in viral infections, immune deficiency syndrome, sickle cell anemia, and hyperfiltration and secondary to interferon therapy. Here, we present a case of FSGS identified with kidney biopsy in a patient who had been diagnosed with Behçet’s disease and received interferon-alpha treatment for uveitis and presented with acute renal failure and nephrotic syndrome associated with interferon.

  4. Focal nodular hyperplasia: imaging findings

    Energy Technology Data Exchange (ETDEWEB)

    Kehagias, D.; Moulopoulos, L.; Antoniou, A.; Hatziioannou, A.; Smyrniotis, V.; Trakadas, S.; Lahanis, S.; Vlahos, L. [Dept. of Radiology, University of Athens (Greece)

    2001-02-01

    Focal nodular hyperplasia is an uncommon benign hepatic tumor that continues to pose diagnostic dilemmas. Imaging techniques are of great value in diagnosis of this tumor. In this article we present the US, CT, MR imaging, scintigraphy, and angiography findings. The demonstration of a central vascular scar is very helpful. Although the radiologic features may be diagnostic, many atypical cases must be differentiated from other benign or malignant hepatic tumors. In these cases excisional biopsy and histopathologic examination are necessary to determine a definite diagnosis. (orig.)

  5. Focal nodular hyperplasia: imaging findings

    International Nuclear Information System (INIS)

    Kehagias, D.; Moulopoulos, L.; Antoniou, A.; Hatziioannou, A.; Smyrniotis, V.; Trakadas, S.; Lahanis, S.; Vlahos, L.

    2001-01-01

    Focal nodular hyperplasia is an uncommon benign hepatic tumor that continues to pose diagnostic dilemmas. Imaging techniques are of great value in diagnosis of this tumor. In this article we present the US, CT, MR imaging, scintigraphy, and angiography findings. The demonstration of a central vascular scar is very helpful. Although the radiologic features may be diagnostic, many atypical cases must be differentiated from other benign or malignant hepatic tumors. In these cases excisional biopsy and histopathologic examination are necessary to determine a definite diagnosis. (orig.)

  6. SNAP Satellite Focal Plane Development

    International Nuclear Information System (INIS)

    Bebek, C.; Akerlof, C.; Aldering, G.; Amanullah, R.; Astier, P.; Baltay, C.; Barrelet, E.; Basa, S.; Bercovitz, J.; Bergstrom, L.; Berstein, G.P.; Bester, M.; Bohlin, R.; Bonissent, A.; Bower, C.; Campbell, M.; Carithers, W.; Commins, E.; Day, C.; Deustua, S.; DiGennaro, R.; Ealet, A.; Ellis, R.; Emmett, W.; Eriksson, M.; Fouchez, D.; Fruchter, A.; Genat, J-F.; Goldhaber, G.; Goobar, A.; Groom, D.; Heetderks, H.; Holland, S.; Huterer, D.; Johnson, W.; Kadel, R.; Karcher, A.; Kim, A.; Kolbe, W.; Lafever, R.; Lamoureaux, J.; Lampton, M.; Lefevre, O.; Levi, M.; Levin, D.; Linder, E.; Loken, S.; Malina, R.; Mazure, A.; McKay, T.; McKee, S.; Miquel, R.; Morgan, N.; Mortsell, E.; Mostek, N.; Mufson, S.; Musser, J.; Roe, N.; Nugent, P.; Oluseyi, H.; Pain, R.; Palaio, N.; Pankow, D.; Perlmutter, S.; Prieto, E.; Rabinowitz, D.; Refregier, A.; Rhodes, J.; Schubnell, M.; Sholl, M.; Smadja, G.; Smith, R.; Smoot, G.; Snyder, J.; Spadafora, A.; Szymkowiak, A.; Tarle, G.; Taylor, K.; Tilquin, A.; Tomasch, A.; Vincent, D.; von der Lippe, H.; Walder, J-P.; Wang, G.

    2003-01-01

    The proposed SuperNova/Acceleration Probe (SNAP) mission will have a two-meter class telescope delivering diffraction-limited images to an instrumented 0.7 square degree field in the visible and near-infrared wavelength regime. The requirements for the instrument suite and the present configuration of the focal plane concept are presented. A two year R and D phase, largely supported by the Department of Energy, is just beginning. We describe the development activities that are taking place to advance our preparedness for mission proposal in the areas of detectors and electronics

  7. MRI of focal cortical dysplasia

    International Nuclear Information System (INIS)

    Lee, B.C.P.; Hatfield, G.A.; Bourgeois, B.; Park, T.S.

    1998-01-01

    We studied nine cases of focal cortical dysplasia (FCD) by MRI, with surface-rendered 3D reconstructions. One case was also examined using single-voxel proton MR spectroscopy (MRS). The histological features were reviewed and correlated with the MRI findings. The gyri affected by FCD were enlarged and the signal of the cortex was slightly increased on T1-weighted images. The gray-white junction was indistinct. Signal from the subcortical white matter was decreased on T1- and increased on T2-weighted images in most cases. Contrast enhancement was seen in two cases. Proton MRS showed a spectrum identical to that of normal brain. (orig.) (orig.)

  8. Using regional moment tensors to constrain the kinematics and stress evolution of the 2010–2013 Canterbury earthquake sequence, South Island, New Zealand

    Science.gov (United States)

    Herman, Matthew W.; Herrmann, Robert B.; Benz, Harley M.; Furlong, Kevin P.

    2014-01-01

    On September 3, 2010, a MW 7.0 (U.S. Geological Survey moment magnitude) earthquake ruptured across the Canterbury Plains in South Island, New Zealand. Since then, New Zealand GNS Science has recorded over 10,000 aftershocks ML 2.0 and larger, including three destructive ~ MW 6.0 earthquakes near Christchurch. We treat the Canterbury earthquake sequence as an intraplate earthquake sequence, and compare its kinematics to an Andersonian model for fault slip in a uniform stress field. We determined moment magnitudes and double couple solutions for 150 earthquakes having MW 3.7 and larger through the use of a waveform inversion technique using data from broadband seismic stations on South Island, New Zealand. The majority (126) of these double couple solutions have strike-slip focal mechanisms, with right-lateral slip on ENE fault planes or equivalently left-lateral slip on SSE fault planes. The remaining focal mechanisms indicate reverse faulting, except for two normal faulting events. The strike-slip segments have compatible orientations for slip in a stress field with a horizontal σ1 oriented ~ N115°E, and horizontal σ3. The preference for right lateral strike-slip earthquakes suggests that these structures are inherited from previous stages of deformation. Reverse slip is interpreted to have occurred on previously existing structures in regions with an absence of existing structures optimally oriented for strike-slip deformation. Despite the variations in slip direction and faulting style, most aftershocks had nearly the same P-axis orientation, consistent with the regional σ1. There is no evidence for significant changes in these stress orientations throughout the Canterbury earthquake sequence.

  9. Idiopathic focal epilepsies: the "lost tribe".

    Science.gov (United States)

    Pal, Deb K; Ferrie, Colin; Addis, Laura; Akiyama, Tomoyuki; Capovilla, Giuseppe; Caraballo, Roberto; de Saint-Martin, Anne; Fejerman, Natalio; Guerrini, Renzo; Hamandi, Khalid; Helbig, Ingo; Ioannides, Andreas A; Kobayashi, Katsuhiro; Lal, Dennis; Lesca, Gaetan; Muhle, Hiltrud; Neubauer, Bernd A; Pisano, Tiziana; Rudolf, Gabrielle; Seegmuller, Caroline; Shibata, Takashi; Smith, Anna; Striano, Pasquale; Strug, Lisa J; Szepetowski, Pierre; Valeta, Thalia; Yoshinaga, Harumi; Koutroumanidis, Michalis

    2016-09-01

    The term idiopathic focal epilepsies of childhood (IFE) is not formally recognised by the ILAE in its 2010 revision (Berg et al., 2010), nor are its members and boundaries precisely delineated. The IFEs are amongst the most commonly encountered epilepsy syndromes affecting children. They are fascinating disorders that hold many "treats" for both clinicians and researchers. For example, the IFEs pose many of the most interesting questions central to epileptology: how are functional brain networks involved in the manifestation of epilepsy? What are the shared mechanisms of comorbidity between epilepsy and neurodevelopmental disorders? How do focal EEG discharges impact cognitive functioning? What explains the age-related expression of these syndromes? Why are EEG discharges and seizures so tightly locked to slow-wave sleep? In the last few decades, the clinical symptomatology and the respective courses of many IFEs have been described, although they are still not widely appreciated beyond the specialist community. Most neurologists would recognise the core syndromes of IFE to comprise: benign epilepsy of childhood with centro-temporal spikes or Rolandic epilepsy (BECTS/RE); Panayiotopoulos syndrome; and the idiopathic occipital epilepsies (Gastaut and photosensitive types). The Landau-Kleffner syndrome and the related (idiopathic) epilepsy with continuous spikes and waves in sleep (CSWS or ESES) are also often included, both as a consequence of the shared morphology of the interictal discharges and their potential evolution from core syndromes, for example, CSWS from BECTS. Atypical benign focal epilepsy of childhood also has shared electro-clinical features warranting inclusion. In addition, a number of less well-defined syndromes of IFE have been proposed, including benign childhood seizures with affective symptoms, benign childhood epilepsy with parietal spikes, benign childhood seizures with frontal or midline spikes, and benign focal seizures of adolescence. The

  10. Stress sensitivity of fault seismicity: A comparison between limited-offset oblique and major strike-slip faults

    Science.gov (United States)

    Parsons, T.; Stein, R.S.; Simpson, R.W.; Reasenberg, P.A.

    1999-01-01

    We present a new three-dimensional inventory of the southern San Francisco Bay area faults and use it to calculate stress applied principally by the 1989 M = 7.1 Loma Prieta earthquake and to compare fault seismicity rates before and after 1989. The major high-angle right-lateral faults exhibit a different response to the stress change than do minor oblique (right-lateral/thrust) faults. Seismicity on oblique-slip faults in the southern Santa Clara Valley thrust belt increased where the faults were unclamped. The strong dependence of seismicity change on normal stress change implies a high coefficient of static friction. In contrast, we observe that faults with significant offset (>50-100 km) behave differently; microseismicity on the Hayward fault diminished where right-lateral shear stress was reduced and where it was unclamped by the Loma Prieta earthquake. We observe a similar response on the San Andreas fault zone in southern California after the Landers earthquake sequence. Additionally, the offshore San Gregorio fault shows a seismicity rate increase where right-lateral/oblique shear stress was increased by the Loma Prieta earthquake despite also being clamped by it. These responses are consistent with either a low coefficient of static friction or high pore fluid pressures within the fault zones. We can explain the different behavior of the two styles of faults if those with large cumulative offset become impermeable through gouge buildup; coseismically pressurized pore fluids could be trapped and negate imposed normal stress changes, whereas in more limited offset faults, fluids could rapidly escape. The difference in behavior between minor and major faults may explain why frictional failure criteria that apply intermediate coefficients of static friction can be effective in describing the broad distributions of aftershocks that follow large earthquakes, since many of these events occur both inside and outside major fault zones.

  11. Fault slip and earthquake recurrence along strike-slip faults — Contributions of high-resolution geomorphic data

    KAUST Repository

    Zielke, Olaf

    2015-01-01

    Understanding earthquake (EQ) recurrence relies on information about the timing and size of past EQ ruptures along a given fault. Knowledge of a fault\\'s rupture history provides valuable information on its potential future behavior, enabling seismic hazard estimates and loss mitigation. Stratigraphic and geomorphic evidence of faulting is used to constrain the recurrence of surface rupturing EQs. Analysis of the latter data sets culminated during the mid-1980s in the formulation of now classical EQ recurrence models, now routinely used to assess seismic hazard. Within the last decade, Light Detection and Ranging (lidar) surveying technology and other high-resolution data sets became increasingly available to tectono-geomorphic studies, promising to contribute to better-informed models of EQ recurrence and slip-accumulation patterns. After reviewing motivation and background, we outline requirements to successfully reconstruct a fault\\'s offset accumulation pattern from geomorphic evidence. We address sources of uncertainty affecting offset measurement and advocate approaches to minimize them. A number of recent studies focus on single-EQ slip distributions and along-fault slip accumulation patterns. We put them in context with paleoseismic studies along the respective faults by comparing coefficients of variation CV for EQ inter-event time and slip-per-event and find that a) single-event offsets vary over a wide range of length-scales and the sources for offset variability differ with length-scale, b) at fault-segment length-scales, single-event offsets are essentially constant, c) along-fault offset accumulation as resolved in the geomorphic record is dominated by essentially same-size, large offset increments, and d) there is generally no one-to-one correlation between the offset accumulation pattern constrained in the geomorphic record and EQ occurrence as identified in the stratigraphic record, revealing the higher resolution and preservation potential of the latter. While slip accumulation along a fault segment may be dominated by repetition of large, nearly constant offset increments, timing of surface-rupture is less regular. (C) 2014 Elsevier B.V. All rights reserved.

  12. Fault slip and earthquake recurrence along strike-slip faults — Contributions of high-resolution geomorphic data

    KAUST Repository

    Zielke, Olaf; Klinger, Yann; Arrowsmith, J. Ramon

    2015-01-01

    to contribute to better-informed models of EQ recurrence and slip-accumulation patterns. After reviewing motivation and background, we outline requirements to successfully reconstruct a fault's offset accumulation pattern from geomorphic evidence. We address

  13. Recurring extensional and strike-slip tectonics after the Neoproterozoic collisional events in the southern Mantiqueira province

    Directory of Open Access Journals (Sweden)

    Renato P. Almeida

    2012-06-01

    Full Text Available In Eastern South America, a series of fault-bounded sedimentary basins that crop out from Southern Uruguay to Southeastern Brazil were formed after the main collisional deformation of the Brasiliano Orogeny and record the tectonic events that affected the region from the Middle Ediacaran onwards. We address the problem of discerning the basin-forming tectonics from the later deformational events through paleostress analysis of more than 600 fault-slip data, mainly from the Camaquã Basin (Southern Brazil, sorted by stratigraphic level and cross-cutting relationships of superposed striations, and integrated with available stratigraphic and geochronological data. Our results show that the Camaquã Basin was formed by at least two distinct extensional events, and that rapid paleostress changes took place in the region a few tens of million years after the major collision (c.a. 630 Ma, probably due to the interplay between local active extensional tectonics and the distal effects of the continued amalgamation of plates and terranes at the margins of the still-forming Gondwana Plate. Preliminary paleostress data from the Castro Basin and published data from the Itajaí Basin suggest that these events had a regional nature.No Leste da América do Sul, um conjunto de bacias sedimentares que afloram do sul do Uruguai ao sudeste do Brasil formou-se após os eventos colisionais da Orogenia Brasiliana, registrando os eventos tectônicos que afetaram a região a partir do Mesoediacarano. O problema da distinção entre a tectônica formadora das bacias e os eventos deformacionais posteriores é aqui abordado através da análise de paleotensões de mais de 600 dados de falhas com estrias, obtidos principalmente na Bacia Camaquã (Sul do Brasil, que foram classificados por nível estratigráfico e relações de corte entre estrias sobrepostas, e intergrados a dados estratigráficos e geocronológicos disponíveis. Nossos resultados revelam que a Bacia Camaquã teve origem em ao menos dois eventos distensivos, e que modificações rápidas no campos de tensões ocorreram na região alguns poucos milhões de anos após a colisão principal (c.a. 630 Ma, provavelmente em decorrência da interação entre esforços distensivos locais e os efeitos distais da contínua amalgamação de placas e terrenos nas margens da placa Gondwana, ainda em formação. Dados preliminares de paleotensões da Bacia de Castro e dados publicados da Bacia Itajaí sugerem que esses eventos tiveram um caráter regional.

  14. RTG diagnostics of dental focal infection

    International Nuclear Information System (INIS)

    Petrasova, A.; Ondrasovicova, J.; Cecctkova, A.

    2008-01-01

    The theory of focal infection has always been and still is a controversial issue for many dentists and scientists. Even though the focal infection does not occupy the first place in modern medicine, its understanding is imperative. The authors summarized the knowledge about dental focal infection and its relationship to systemic the diseases of the whole body in their publication and they also focused on the radiodiagnostics of this disease. (authors)

  15. Flux dynamics in ultrasensitive superconducting focal planes

    Data.gov (United States)

    National Aeronautics and Space Administration — The performance of superconducting focal planes will drive the achievable specifications of ultrasensitive instruments for NASA astrophysics missions, yet they have...

  16. Game Movement as Enactive Focalization

    Directory of Open Access Journals (Sweden)

    Yotam Shibolet

    2018-01-01

    Full Text Available This paper integrates thought on game narrative and embodied cognition, in order to consider the significance of movement to the embodied narrative experience of games. If games are a mode of ‘environmental storytelling’, determining the player’s mobile situatedness within the gamespace is of crucial importance. The metaphor of game design as narrative architecture should be expanded to include te the design of movement dynamics, alongside geographical gamespace. I suggest a theoretical infrastructure that aims to enable further analysis of movement design’s role in this scope. The theory of enactive perception asserts that all perception is inherently negotiated through embodied understanding of moving within environment. According to this model, by giving meaning to perception, movement is also directly related to the structure of consciousness and thought. Cognitive definitions of ‘narrative’ that integrate embodiment are applied to argue it can relevantly account for part of thought’s role in enactive perception. Mieke Bal’s concept of focalization (1997 broaches narrative perspective by underscoring the constant “movement of the look”. For enactive perception, such mobility should be understood as inseparable from the movement of the body even when perspective could appear detached from embodiment. Therefore, I offer the supplementary concept of “enactive focalization” – narrative perception as interpreted through the interconnected dynamics or perspectival and physical movement. To exemplify my ideas and the potential of future research in this scope, I discuss the uniquely effective and affective movement dynamic design of Journey. This paper concludes by reflecting on enactive focalization in light of the increased utilization of embodiment in the contemporary digital media landscape.

  17. Prenatal sonographic diagnosis of focal musculoskeletal anomalies

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Jung Kyu; Cho, Jeong Yeon; Lee, Young Ho; Kim, Ei Jeong; Chun, Yi Kyeong [Samsung Cheil Hospital, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2002-09-15

    Focal musculoskeletal anomalies are various and may be an isolated finding or may be found in conjunction with numerous associations, including genetic syndromes, Karyotype abnormals, central nervous system anomalies and other general musculoskeletal disorders. Early prenatal diagnosis of these focal musculoskeletal anomalies nor only affects prenatal care and postnatal outcome but also helps in approaching other numerous associated anomalies.

  18. Prenatal sonographic diagnosis of focal musculoskeletal anomalies

    International Nuclear Information System (INIS)

    Ryu, Jung Kyu; Cho, Jeong Yeon; Lee, Young Ho; Kim, Ei Jeong; Chun, Yi Kyeong

    2002-01-01

    Focal musculoskeletal anomalies are various and may be an isolated finding or may be found in conjunction with numerous associations, including genetic syndromes, Karyotype abnormals, central nervous system anomalies and other general musculoskeletal disorders. Early prenatal diagnosis of these focal musculoskeletal anomalies nor only affects prenatal care and postnatal outcome but also helps in approaching other numerous associated anomalies.

  19. Early vision and focal attention

    Science.gov (United States)

    Julesz, Bela

    1991-07-01

    At the thirty-year anniversary of the introduction of the technique of computer-generated random-dot stereograms and random-dot cinematograms into psychology, the impact of the technique on brain research and on the study of artificial intelligence is reviewed. The main finding-that stereoscopic depth perception (stereopsis), motion perception, and preattentive texture discrimination are basically bottom-up processes, which occur without the help of the top-down processes of cognition and semantic memory-greatly simplifies the study of these processes of early vision and permits the linking of human perception with monkey neurophysiology. Particularly interesting are the unexpected findings that stereopsis (assumed to be local) is a global process, while texture discrimination (assumed to be a global process, governed by statistics) is local, based on some conspicuous local features (textons). It is shown that the top-down process of "shape (depth) from shading" does not affect stereopsis, and some of the models of machine vision are evaluated. The asymmetry effect of human texture discrimination is discussed, together with recent nonlinear spatial filter models and a novel extension of the texton theory that can cope with the asymmetry problem. This didactic review attempts to introduce the physicist to the field of psychobiology and its problems-including metascientific problems of brain research, problems of scientific creativity, the state of artificial intelligence research (including connectionist neural networks) aimed at modeling brain activity, and the fundamental role of focal attention in mental events.

  20. Flotillins Regulate Focal Adhesions by Interacting with α-Actinin and by Influencing the Activation of Focal Adhesion Kinase

    Directory of Open Access Journals (Sweden)

    Antje Banning

    2018-04-01

    Full Text Available Cell–matrix adhesion and cell migration are physiologically important processes that also play a major role in cancer spreading. In cultured cells, matrix adhesion depends on integrin-containing contacts such as focal adhesions. Flotillin-1 and flotillin-2 are frequently overexpressed in cancers and are associated with poor survival. Our previous studies have revealed a role for flotillin-2 in cell–matrix adhesion and in the regulation of the actin cytoskeleton. We here show that flotillins are important for cell migration in a wound healing assay and influence the morphology and dynamics of focal adhesions. Furthermore, anchorage-independent growth in soft agar is enhanced by flotillins. In the absence of flotillins, especially flotillin-2, phosphorylation of focal adhesion kinase and extracellularly regulated kinase is diminished. Flotillins interact with α-actinin, a major regulator of focal adhesion dynamics. These findings are important for understanding the molecular mechanisms of how flotillin overexpression in cancers may affect cell migration and, especially, enhance metastasis formation.

  1. Nitric oxide synthase-I containing cortical interneurons co-express antioxidative enzymes and anti-apoptotic Bcl-2 following focal ischemia: evidence for direct and indirect mechanisms towards their resistance to neuropathology.

    Science.gov (United States)

    Bidmon, H J; Emde, B; Kowalski, T; Schmitt, M; Mayer, B; Kato, K; Asayama, K; Witte, O W; Zilles, K

    2001-09-01

    Neuronal nitric oxide-I is constitutively expressed in approximately 2% of cortical interneurons and is co-localized with gamma-amino butric acid, somatostatin or neuropeptide Y. These interneurons additionally express high amounts of glutamate receptors which mediate the glutamate-induced hyperexcitation following cerebral injury, under these conditions nitric oxide production increases contributing to a potentiation of oxidative stress. However, perilesional nitric oxide synthase-I containing neurons are known to be resistant to ischemic and excitotoxic injury. In vitro studies show that nitrosonium and nitroxyl ions inactivate N-methyl-D-aspartate receptors, resulting in neuroprotection. The question remains of how these cells are protected against their own high intracellular nitric oxide production after activation. In this study, we investigated immunocytochemically nitric oxide synthase-I containing cortical neurons in rats after unilateral, cortical photothrombosis. In this model of focal ischemia, perilesional, constitutively nitric oxide synthase-I containing neurons survived and co-expressed antioxidative enzymes, such as manganese- and copper-zinc-dependent superoxide dismutases, heme oxygenase-2 and cytosolic glutathione peroxidase. This enhanced antioxidant expression was accompanied by a strong perinuclear presence of the antiapoptotic Bcl-2 protein. No colocalization was detectable with upregulated heme oxygenase-1 in glia and the superoxide and prostaglandin G(2)-producing cyclooxygenase-2 in neurons. These results suggest that nitric oxide synthase-I containing interneurons are protected against intracellular oxidative damage and apoptosis by Bcl-2 and several potent antioxidative enzymes. Since nitric oxide synthase-I positive neurons do not express superoxide-producing enzymes such as cyclooxygenase-1, xanthine oxidase and cyclooxygenase-2 in response to injury, this may additionally contribute to their resistance by reducing their internal

  2. METHOD FOR DETERMINATION OF FOCAL PLANE LOCATION OF FOCUSING COMPONENTS

    Directory of Open Access Journals (Sweden)

    A. I. Ivashko

    2017-01-01

    Full Text Available Mass-production of different laser systems often requires utilization of the focal spot size method for determination of output laser beam spatial characteristics. The main challenge of this method is high accuracy maintenance of a CCD camera beam profiler in the collecting lens focal plane. The aim of our work is development of new method for placing of photodetector array in the collecting lens focal plane with high accuracy.Proposed technique is based on focusing of several parallel laser beams. Determination of the focal plane position requires only longitudinal translation of the CCD-camera to find a point of laser beams intersection. Continuous-wave (CW diode-pumped laser emitting in the spectral region near 1μm was created to satisfy the requirements of the developed technique. Designed microchip laser generates two stigmatic Gaussian beams with automatically parallel beam axes due to independent pumping of different areas of the one microchip crystal having the same cavity mirrors.It was theoretically demonstrated that developed method provides possibility of the lenses focal plane determination with 1 % accuracy. The microchip laser generates two parallel Gaussian beams with divergence of about 10 mrad. Laser output power can be varied in the range of 0.1–1.5 W by changing the pumping laser diode electrical current. The distance between two beam axes can be changed in the range of 0.5–5.0 mm.We have proposed method for determination of positive lens focal plane location by using of CCDcamera and two laser beams with parallel axes without utilization of additional optical devices. We have developed CW longitudinally diode pumped microchip laser emitting in the 1-μm spectral region that can be used in the measuring instrument that doesn’t require precision mechanical components for determination of focal plane location with 1 % accuracy. The overall dimensions of laser head was 70 × 40 × 40 mm3 and maximum power consumption was

  3. Do focal colors look particularly "colorful"?

    Science.gov (United States)

    Witzel, Christoph; Franklin, Anna

    2014-04-01

    If the most typical red, yellow, green, and blue were particularly colorful (i.e., saturated), they would "jump out to the eye." This would explain why even fundamentally different languages have distinct color terms for these focal colors, and why unique hues play a prominent role in subjective color appearance. In this study, the subjective saturation of 10 colors around each of these focal colors was measured through a pairwise matching task. Results show that subjective saturation changes systematically across hues in a way that is strongly correlated to the visual gamut, and exponentially related to sensitivity but not to focal colors.

  4. Focal pancreatic enlargement: differentiation between pancreatic adenocarcinoma and focal pancreatitis on CT and ERCP

    International Nuclear Information System (INIS)

    Kim, Eun Kyung; Kim, Ki Whang; Lee, Jong Tae; Kim, Hee Soo; Yoo, Hyung Sik; Yu, Jeong Sik; Yoon, Sang Wook

    1995-01-01

    To differentiate the pancreatic adenocarcinoma from focal pancreatitis on CT and ERCP in cases of focal pancreatic enlargement. We analysed CT findings of 66 patients of pancreatic adenocarcinoma (n = 45) or focal pancreatitis (n = 21) with respect to size, density, calcification, pancreatic or biliary duct dilatation, fat plane obliteration around the vessels, direction of retroperitoneal extension, lymphadenopathy, pseudocyst formation and atrophy of pancreas. ERCP available in 48 patients were analysed in respect to morphologic appearance of CBD and pancreatic duct, and distance between the two ducts. The patients in focal pancreatitis were younger with more common history of alcohol drinking. There was no statistical difference in calcifications of the mass (18% in the adenocarcinoma, 33% in the focal pancreatitis), but a tendency of denser, larger number of calcifications was noted in focal pancreatitis. The finding of fat plane obliteration around the vessels were more common in pancreatic adenocarcinoma, and fascial thickenings were more prominent in focal pancreatitis, although not statistically significant. On ERCP, there were no differential points of CBD, pancreatic duct morphology, but distance between the two ducts at the lesion center was more wider in focal pancreatitis. Differentiating focal pancreatitis from pancreatic adenocarcinoma is difficult. However, we should consider the possibility of focal pancreatitis in cases of patients with young age, having alcoholic history in association with CT findings of large numbers of and dense calcifications, and ERCP findings of prominent separation of two duct at the lesion center

  5. Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-mediated Contractility via Activation of Focal Adhesion Kinase and Extra Cellular-regulated Kinase 1/2 in Cerebral Arteries from Rat

    DEFF Research Database (Denmark)

    Spray, Stine; Rasmussen, Marianne N P; Skovsted, Gry F

    2016-01-01

    that rapid and sustained reduction in wall tension/stretch is a possible trigger mechanism for this vascular remodelling. Isolated rat middle cerebral artery (MCA) segments were incubated in a wire-myograph with or without mechanical stretch, prior to assessment of their contractile response to the selective...... expression to SMC expression and 2) an increased calcium sensitivity of the SMCs due to an increased expression of the calcium channel transient receptor potential canonical 1. Collectively, our results present a possible mechanism linking lack of vessel wall stretch/tension to changes in ETB receptor...

  6. Seismicity of the 24 May 2014 Mw 7.0 Aegean Sea earthquake sequence along the North Aegean Trough

    Science.gov (United States)

    Görgün, Ethem; Görgün, Burçak

    2015-11-01

    The northern Aegean Sea was hit by a large size (Mw = 7.0) earthquake on 2014 May 24. Centroid moment tensor solutions for 40 events with moment magnitudes (Mw) between 3.3 and 7.0 are computed by applying a waveform inversion method on data from the Turkish and Greek broadband seismic networks. The time span of data covers the period between 2014 May 24 and 2014 June 26. The mainshock is a shallow focus strike-slip event at a depth of 15 km. Focal depths of aftershocks range from 6 to 30 km. The seismic moment (Mo) of the mainshock is estimated as 4.60 × 1019 Nm. The calculated rupture duration of the North Aegean Sea mainshock is 40 s. The focal mechanisms of the aftershocks are mainly strike-slip faulting with a minor normal component. The geometry of focal mechanisms reveals a strike-slip faulting regime with NE-SW trending direction of T-axis in the entire activated region. A stress tensor inversion of focal mechanism data is performed to acquire a more accurate picture of the northern Aegean Sea stress field along the North Aegean Trough. The stress tensor inversion results indicate a predominant strike-slip stress regime with a NW-SE oriented maximum principal compressive stress (σ1). In the development of the North Aegean Trough in Aegean Sea is in good agreement with the resolved stress tensors. With respect the newly determined focal mechanisms, the effect of the propagating of the North Anatolian Fault into Aegean Sea is very clearly pronounced. According to high-resolution hypocenter relocation of the North Aegean Sea seismic sequence, three main clusters are revealed. The aftershock activity in the observation period between 2014 May 24 and 2014 July 31 extends from the mainshock cluster from NE to the SW direction. Seismic cross-sections indicate that a complex pattern of the hypocenter distribution with the activation of seventeen segments. The eastern cluster is associated with a fault plane trending mainly ENE-WSW and dipping vertical, while the

  7. Uncooled infrared focal plane array imaging in China

    Science.gov (United States)

    Lei, Shuyu

    2015-06-01

    This article reviews the development of uncooled infrared focal plane array (UIFPA) imaging in China in the past decade. Sensors based on optical or electrical read-out mechanism were developed but the latter dominates the market. In resistive bolometers, VOx and amorphous silicon are still the two major thermal-sensing materials. The specifications of the IRFPA made by different manufactures were collected and compared. Currently more than five Chinese companies and institutions design and fabricate uncooled infrared focal plane array. Some devices have sensitivity as high as 30 mK; the largest array for commercial products is 640×512 and the smallest pixel size is 17 μm. Emphasis is given on the pixel MEMS design, ROIC design, fabrication, and packaging of the IRFPA manufactured by GWIC, especially on design for high sensitivities, low noise, better uniformity and linearity, better stabilization for whole working temperature range, full-digital design, etc.

  8. Focal skin defect, limb anomalies and microphthalmia.

    NARCIS (Netherlands)

    Jackson, K.E.; Andersson, H.C.

    2004-01-01

    We describe two unrelated female patients with congenital single focal skin defects, unilateral microphthalmia and limb anomalies. Growth and psychomotor development were normal and no brain malformation was detected. Although eye and limb anomalies are commonly associated, clinical anophthalmia and

  9. Genetics Home Reference: focal dermal hypoplasia

    Science.gov (United States)

    ... in people with focal dermal hypoplasia is an omphalocele , which is an opening in the wall of ... Dermal Hypoplasia MedlinePlus Encyclopedia: Ectodermal dysplasia MedlinePlus Encyclopedia: Omphalocele General Information from MedlinePlus (5 links) Diagnostic Tests ...

  10. Focal lesions in the central nervous system

    International Nuclear Information System (INIS)

    Fabrikant, J.I.; Budinger, T.F.; Tobias, C.A.; Born, J.L.

    1980-01-01

    This report reviews the animal and human studies currently in progress at LBL with heavy-ion beams to induce focal lesions in the central nervous system, and discusses the potential future prospects of fundamental and applied brain research with heavy-ion beams. Methods are being developed for producing discrete focal lesions in the central nervous system using the Bragg ionization peak to investigate nerve pathways and neuroendocrine responses, and for treating pathological disorders of the brain

  11. The 12th June 2017 Mw = 6.3 Lesvos earthquake from detailed seismological observations

    Science.gov (United States)

    Papadimitriou, P.; Kassaras, I.; Kaviris, G.; Tselentis, G.-A.; Voulgaris, N.; Lekkas, E.; Chouliaras, G.; Evangelidis, C.; Pavlou, K.; Kapetanidis, V.; Karakonstantis, A.; Kazantzidou-Firtinidou, D.; Fountoulakis, I.; Millas, C.; Spingos, I.; Aspiotis, T.; Moumoulidou, A.; Skourtsos, E.; Antoniou, V.; Andreadakis, E.; Mavroulis, S.; Kleanthi, M.

    2018-04-01

    A major earthquake (Mwö=ö6.3) occurred on the 12th of June 2017 (12:28 GMT) offshore, south of the SE coast of Lesvos Island, at a depth of 13ökm, in an area characterized by normal faulting with an important strike-slip component in certain cases. Over 900 events of the sequence between 12 and 30 June 2017 were manually analyzed and located, employing an optimized local velocity model. Double-difference relocation revealed seven spatially separated groups of events, forming two linear branches, roughly aligned N130°E, compatible with the strike of known mapped faults along the southern coast of Lesvos Island. Spatiotemporal analysis indicated gradual migration of seismicity towards NW and SE from the margins of the main rupture, while a strong secondary sequence at a separate fault patch SE of the mainshock, oriented NW-SE, was triggered by the largest aftershock (Mwö=ö5.2) that occurred on 17 June. The focal mechanisms of the mainshock (φö=ö122°, δö=ö40° and λö=ö-83°) and of the major aftershocks were determined using regional moment tensor inversion. In most cases normal faulting was revealed with the fault plane oriented in a NW-SE direction, dipping SW, with the exception of the largest aftershock that was characterized by strike-slip faulting. Stress inversion revealed a complex stress field south of Lesvos, related both to normal, in an approximate E-W direction, and strike-slip faulting. All aftershocks outside the main rupture, where gradual seismicity migration was observed, are located within the positive lobes of static stress transfer determined by applying the Coulomb criterion for the mainshock. Stress loading on optimal faults under a strike-slip regime explains the occurrence of the largest aftershock and the seismicity that was triggered at the eastern patch of the rupture zone.

  12. Tectonic implications of the 2017 Ayvacık (Çanakkale) earthquakes, Biga Peninsula, NW Turkey

    Science.gov (United States)

    Özden, Süha; Över, Semir; Poyraz, Selda Altuncu; Güneş, Yavuz; Pınar, Ali

    2018-04-01

    The west to southwestward motion of the Anatolian block results from the relative motions between the Eurasian, Arabian and African plates along the right-lateral North Anatolian Fault Zone in the north and left-lateral East Anatolian Fault Zone in the east. The Biga Peninsula is tectonically influenced by the Anatolian motion originating along the North Anatolian Fault Zone which splits into two main (northern and southern) branches in the east of Marmara region: the southern branch extends towards the Biga Peninsula which is characterized by strike-slip to oblique normal faulting stress regime in the central to northern part. The southernmost part of peninsula is characterized by a normal to oblique faulting stress regime. The analysis of both seismological and structural field data confirms the change of stress regime from strike-slip character in the center and north to normal faulting character in the south of peninsula where the earthquake swarm recently occurred. The earthquakes began on 14 January 2017 (Mw: 4.4) on Tuzla Fault and migrated southward along the Kocaköy and Babakale's stepped-normal faults of over three months. The inversion of focal mechanisms yields a normal faulting stress regime with an approximately N-S (N4°E) σ3 axis. The inversion of earthquakes occurring in central and northern Biga Peninsula and the north Aegean region gives a strike-slip stress regime with approximately WNW-ESE (N85°W) σ1 and NNE-SSW (N17°E) σ3 axis. The strike-slip stress regime is attributed to westward Anatolian motion, while the normal faulting stress regime is attributed to both the extrusion of Anatolian block and the slab-pull force of the subducting African plate along the Hellenic arc.

  13. Sighting optics including an optical element having a first focal length and a second focal length

    Science.gov (United States)

    Crandall, David Lynn [Idaho Falls, ID

    2011-08-01

    One embodiment of sighting optics according to the teachings provided herein may include a front sight and a rear sight positioned in spaced-apart relation. The rear sight includes an optical element having a first focal length and a second focal length. The first focal length is selected so that it is about equal to a distance separating the optical element and the front sight and the second focal length is selected so that it is about equal to a target distance. The optical element thus brings into simultaneous focus, for a user, images of the front sight and the target.

  14. Transparent meta-analysis: does aging spare prospective memory with focal vs. non-focal cues?

    Directory of Open Access Journals (Sweden)

    Bob Uttl

    Full Text Available BACKGROUND: Prospective memory (ProM is the ability to become aware of a previously-formed plan at the right time and place. For over twenty years, researchers have been debating whether prospective memory declines with aging or whether it is spared by aging and, most recently, whether aging spares prospective memory with focal vs. non-focal cues. Two recent meta-analyses examining these claims did not include all relevant studies and ignored prevalent ceiling effects, age confounds, and did not distinguish between prospective memory subdomains (e.g., ProM proper, vigilance, habitual ProM (see Uttl, 2008, PLoS ONE. The present meta-analysis focuses on the following questions: Does prospective memory decline with aging? Does prospective memory with focal vs. non-focal cues decline with aging? Does the size of age-related declines with focal vs. non-focal cues vary across ProM subdomains? And are age-related declines in ProM smaller than age-related declines in retrospective memory? METHODS AND FINDINGS: A meta-analysis of event-cued ProM using data visualization and modeling, robust count methods, and conventional meta-analysis techniques revealed that first, the size of age-related declines in ProM with both focal and non-focal cues are large. Second, age-related declines in ProM with focal cues are larger in ProM proper and smaller in vigilance. Third, age-related declines in ProM proper with focal cues are as large as age-related declines in recall measures of retrospective memory. CONCLUSIONS: The results are consistent with Craik's (1983 proposal that age-related declines on ProM tasks are generally large, support the distinction between ProM proper vs. vigilance, and directly contradict widespread claims that ProM, with or without focal cues, is spared by aging.

  15. Focal thyroid inferno” on color Doppler ultrasonography: A specific feature of focal Hashimoto's thyroiditis

    International Nuclear Information System (INIS)

    Fu, Xianshui; Guo, Limei; Zhang, Huabin; Ran, Weiqiang; Fu, Peng; Li, Zhiqiang; Chen, Wen; Jiang, Ling; Wang, Jinrui; Jia, Jianwen

    2012-01-01

    Purpose: To evaluate color-Doppler features predictive of focal Hashimoto's thyroiditis. Materials and methods: A total of 521 patients with 561 thyroid nodules that underwent surgeries or gun biopsies were included in this study. These nodules were divided into three groups: focal Hashimoto's thyroiditis (104 nodules in 101 patients), benignity other than focal Hashimoto's thyroiditis (73 nodules in 70 patients), and malignancy (358 nodules in 350 patients). On color Doppler sonography, four vascularity types were determined as: hypovascularity, marked internal flow, marked peripheral flow and focal thyroid inferno. The χ 2 test was performed to seek the potential vascularity type with the predictive ability of certain thyroid pathology. Furthermore, the gray-scale features of each nodule were also studied. Results: The vascularity type I (hypovascularity) was more often seen in focal Hashimoto's thyroiditis than other benignity and malignancy (46% vs. 20.5% and 19%). While the type II (marked internal flow) showed the opposite tendency (26.9% [focal Hashimoto's thyroiditis] vs. 45.2% [other benignity] and 52.8% [malignancy]). However, type III (marked peripheral flow) was unable to predict any thyroid pathology. Importantly, type IV (focal thyroid inferno) was exclusive to focal Hashimoto's thyroiditis. All 8 type IV nodules appeared to be solid, hypoechoic, and well-defined. Using “focal thyroid inferno” as an indicator of FHT, the diagnostic sensitivity and specificity were 7.7% and 100% respectively. Conclusions: The vascularity type of “focal thyroid inferno” is specific for focal Hashimoto thyroiditis. Recognition of this particular feature may avoid unnecessary interventional procedures for some solid hypoechoic thyroid nodules suspicious of malignancy.

  16. Prenatal sonographic diagnosis of focal musculoskeletal anomalies

    International Nuclear Information System (INIS)

    Ryu, Jung-Kyu; Cho, Jeong-Yeon; Choi, Jong-Sun

    2003-01-01

    Focal musculoskeletal anomalies vary, and can manifest as part of a syndrome or be accompanied by numerous other conditions such as genetic disorders, karyotype abnormalities, central nervous system anomalies and other skeletal anomalies, lsolated focal musculoskeletal anomaly does, however, also occur; its early prenatal diagnosis is important in deciding prenatal care, and also helps in counseling parents about the postnatal effects of numerous possible associated anomalies. We have encountered 50 cases involving focal musculoskeletal anomalies, including total limb dysplasia [radial ray abnormality (n=3), mesomelic dysplasia (n=1)]; anomalies of the hand [polydactyly (n=8), syndactyly (n=3), ectrodactyly (n=1), clinodactyly (n=6), clenched hand (n=5)]; anomalies of the foot [clubfoot (n=10), rockerbottom foot (n=5), sandal gap deformity (n=1), curly toe (n=2)]; amniotic band syndrome (n=3); and anomalies of the focal spine [block vertebra (n=1), hemivertebra (n=1)]. Among these 50 cases, five [polydactyly (n=1), syndactyly (n=2) and curly toe (n=2) were confirmed by postnatal physical evaluation, two (focal spine anomalies) were diagnosed after postnatal radiologic examination, and the remaining 43 were proven at autopsy. For each condition, we describe the prenatal sonographic findings, and include a brief review

  17. Prenatal sonographic diagnosis of focal musculoskeletal anomalies

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Jung-Kyu; Cho, Jeong-Yeon; Choi, Jong-Sun [Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2003-12-15

    Focal musculoskeletal anomalies vary, and can manifest as part of a syndrome or be accompanied by numerous other conditions such as genetic disorders, karyotype abnormalities, central nervous system anomalies and other skeletal anomalies, lsolated focal musculoskeletal anomaly does, however, also occur; its early prenatal diagnosis is important in deciding prenatal care, and also helps in counseling parents about the postnatal effects of numerous possible associated anomalies. We have encountered 50 cases involving focal musculoskeletal anomalies, including total limb dysplasia [radial ray abnormality (n=3), mesomelic dysplasia (n=1)]; anomalies of the hand [polydactyly (n=8), syndactyly (n=3), ectrodactyly (n=1), clinodactyly (n=6), clenched hand (n=5)]; anomalies of the foot [clubfoot (n=10), rockerbottom foot (n=5), sandal gap deformity (n=1), curly toe (n=2)]; amniotic band syndrome (n=3); and anomalies of the focal spine [block vertebra (n=1), hemivertebra (n=1)]. Among these 50 cases, five [polydactyly (n=1), syndactyly (n=2) and curly toe (n=2) were confirmed by postnatal physical evaluation, two (focal spine anomalies) were diagnosed after postnatal radiologic examination, and the remaining 43 were proven at autopsy. For each condition, we describe the prenatal sonographic findings, and include a brief review.

  18. Seven tesla MRI improves detection of focal cortical dysplasia in patients with refractory focal epilepsy

    NARCIS (Netherlands)

    Veersema, Tim J; Ferrier, Cyrille H; van Eijsden, Pieter; Gosselaar, Peter H; Aronica, Eleonora; Visser, Fredy; Zwanenburg, Jaco M; de Kort, Gerard A P; Hendrikse, Jeroen; Luijten, Peter R; Braun, Kees P J

    Objective: The aim of this study is to determine whether the use of 7 tesla (T) MRI in clinical practice leads to higher detection rates of focal cortical dysplasias in possible candidates for epilepsy surgery. Methods: In our center patients are referred for 7 T MRI if lesional focal epilepsy is

  19. Expansive focal cemento-osseous dysplasia.

    Science.gov (United States)

    Bulut, Emel Uzun; Acikgoz, Aydan; Ozan, Bora; Zengin, Ayse Zeynep; Gunhan, Omer

    2012-01-01

    To present a case of expansive focal cemento-osseous dysplasia and emphasize the importance of differential diagnosis. Cemento-osseous dysplasia is categorized into three subtypes on the basis of the clinical and radiographic features: Periapical, focal and florid. The focal type exhibits a single site of involvement in any tooth-bearing or edentulous area of the jaws. These lesions are usually asymptomatic; therefore, they are frequently diagnosed incidentally during routine radiographic examinations. Lesions are usually benign, show limited growth, and do not require further surgical intervention, but periodic follow-up is recommended because occasionally, this type of dysplasia progresses into florid osseous dysplasia and simple bone cysts are formed. A 24-year-old female patient was referred to our clinic for swelling in the left edentulous mandibular premolarmolar region and felt discomfort when she wore her prosthetics. She had no pain, tenderness or paresthesia. Clinical examination showed that the swelling in the posterior mandible that was firm, nonfluctuant and covered by normal mucosa. On panoramic radiography and computed tomography, a well defined lesion of approximately 1.5 cm in diameter of mixed density was observed. The swelling increased slightly in size over 2 years making it difficult to use prosthetics and, therefore, the lesion was totally excised under local anesthesia, and surgical specimens were submitted for histopathological examination. The histopathological diagnosis was focal cemento-osseous dysplasia. In the present case, because of the increasing size of the swelling making it difficult to use prosthetics, young age of the patient and localization of the lesion, in the initial examination, cemento-ossifying fibroma was suspected, and the lesion was excised surgically; the histopathological diagnosis confirmed it as focal cemento-osseous dysplasia. We present a case of expansive focal cemento-osseous dysplasia. Differential diagnosis

  20. Extensive Focal Epithelial Hyperplasia: A Case Report.

    Science.gov (United States)

    Mansouri, Zahra; Bakhtiari, Sedigheh; Noormohamadi, Robab

    2015-01-01

    Focal epithelial hyperplasia (FEH) or Heck's disease is a rare viral infection of the oral mucosa caused by human papilloma virus especially subtypes 13 or 32. The frequency of this disease varies widely from one geographic region and ethnic groups to another. This paper reports an Iranian case of extensive focal epithelial hyperplasia. A 35-year-old man with FEH is described, in whom the lesions had persisted for more than 25 years. The lesion was diagnosed according to both clinical and histopathological features. Dental practitioner should be aware of these types of lesions and histopathological examination together and a careful clinical observation should be carried out for a definitive diagnosis.

  1. Rasmussen's encephalitis presenting as focal cortical dysplasia

    Directory of Open Access Journals (Sweden)

    D.J. O'Rourke

    2014-01-01

    Full Text Available Rasmussen's encephalitis is a rare syndrome characterized by intractable seizures, often associated with epilepsia partialis continua and symptoms of progressive hemispheric dysfunction. Seizures are usually the hallmark of presentation, but antiepileptic drug treatment fails in most patients and is ineffective against epilepsia partialis continua, which often requires surgical intervention. Co-occurrence of focal cortical dysplasia has only rarely been described and may have implications regarding pathophysiology and management. We describe a rare case of dual pathology of Rasmussen's encephalitis presenting as a focal cortical dysplasia (FCD and discuss the literature on this topic.

  2. Rasmussen's encephalitis presenting as focal cortical dysplasia

    Science.gov (United States)

    O'Rourke, D.J.; Bergin, A.; Rotenberg, A.; Peters, J.; Gorman, M.; Poduri, A.; Cryan, J.; Lidov, H.; Madsen, J.; Harini, C.

    2014-01-01

    Rasmussen's encephalitis is a rare syndrome characterized by intractable seizures, often associated with epilepsia partialis continua and symptoms of progressive hemispheric dysfunction. Seizures are usually the hallmark of presentation, but antiepileptic drug treatment fails in most patients and is ineffective against epilepsia partialis continua, which often requires surgical intervention. Co-occurrence of focal cortical dysplasia has only rarely been described and may have implications regarding pathophysiology and management. We describe a rare case of dual pathology of Rasmussen's encephalitis presenting as a focal cortical dysplasia (FCD) and discuss the literature on this topic. PMID:25667877

  3. Actinic Granuloma with Focal Segmental Glomerulosclerosis

    Directory of Open Access Journals (Sweden)

    Ruedee Phasukthaworn

    2016-02-01

    Full Text Available Actinic granuloma is an uncommon granulomatous disease, characterized by annular erythematous plaque with central clearing predominately located on sun-damaged skin. The pathogenesis is not well understood, ultraviolet radiation is recognized as precipitating factor. We report a case of a 52-year-old woman who presented with asymptomatic annular erythematous plaques on the forehead and both cheeks persisting for 2 years. The clinical presentation and histopathologic findings support the diagnosis of actinic granuloma. During that period of time, she also developed focal segmental glomerulosclerosis. The association between actinic granuloma and focal segmental glomerulosclerosis needs to be clarified by further studies.

  4. Focal splenic masses of the extramedullary hematopoiesis

    International Nuclear Information System (INIS)

    Incedayi, M.; Sivrioglu, A.

    2012-01-01

    Full text: Extramedullary hematopoiesis arises from pleuripotential stem cells distributed throughout the body. It is most common in patients with congenital hemolytic anemia, such as thalassemia, sickle cell anemia and hereditary spherocytosis as a response to ineffective red blood cell formation. Although microscopic foci of Extramedullary hematopoiesis are commonly seen in the spleen and liver parenchyma, focal mass-like lesion of extramedullary hematopoiesis in the liver and spleen are rare. We report a case of intrasplenic focal extramedullary hematopoiesis lesions and the imaging features of extramedullary hematopoiesis on computed tomography and magnetic resonance imaging. Extramedullary hematopoiesis should always be considered as a diagnosis in a patient with a known hematological disorder

  5. Causal mechanisms of seismo-EM phenomena during the 1965-1967 Matsushiro earthquake swarm

    Science.gov (United States)

    Enomoto, Yuji; Yamabe, Tsuneaki; Okumura, Nobuo

    2017-03-01

    The 1965-1967 Matsushiro earthquake swarm in central Japan exhibited two unique characteristics. The first was a hydro-mechanical crust rupture resulting from degassing, volume expansion of CO2/water, and a crack opening within the critically stressed crust under a strike-slip stress. The other was, despite the lower total seismic energy, the occurrence of complexed seismo-electromagnetic (seismo-EM) phenomena of the geomagnetic intensity increase, unusual earthquake lights (EQLs) and atmospheric electric field (AEF) variations. Although the basic rupture process of this swarm of earthquakes is reasonably understood in terms of hydro-mechanical crust rupture, the associated seismo-EM processes remain largely unexplained. Here, we describe a series of seismo-EM mechanisms involved in the hydro-mechanical rupture process, as observed by coupling the electric interaction of rock rupture with CO2 gas and the dielectric-barrier discharge of the modelled fields in laboratory experiments. We found that CO2 gases passing through the newly created fracture surface of the rock were electrified to generate pressure-impressed current/electric dipoles, which could induce a magnetic field following Biot-Savart’s law, decrease the atmospheric electric field and generate dielectric-barrier discharge lightning affected by the coupling effect between the seismic and meteorological activities.

  6. A bottom-driven mechanism for distributed faulting: Insights from the Gulf of California Rift

    Science.gov (United States)

    Persaud, P.; Tan, E.; Choi, E.; Contreras, J.; Lavier, L. L.

    2017-12-01

    The Gulf of California is a young oblique rift that displays a variation in rifting style along strike. Despite the rapid localization of strain in the Gulf at 6 Ma, the northern rift segment has the characteristics of a wide rift, with broadly distributed extensional strain and small gradients in topography and crustal thinning. Observations of active faulting in the continent-ocean transition of the Northern Gulf show multiple oblique-slip faults distributed in a 200 x 70 km2area developed some time after a westward relocation of the plate boundary at 2 Ma. In contrast, north and south of this broad pull-apart structure, major transform faults accommodate Pacific-North America plate motion. Here we propose that the mechanism for distributed brittle deformation results from the boundary conditions present in the Northern Gulf, where basal shear is distributed between the Cerro Prieto strike-slip fault (southernmost fault of the San Andreas fault system) and the Ballenas Transform fault. We hypothesize that in oblique-extensional settings whether deformation is partitioned in a few dip-slip and strike-slip faults, or in numerous oblique-slip faults may depend on (1) bottom-driven, distributed extension and shear deformation of the lower crust or upper mantle, and (2) the rift obliquity. To test this idea, we explore the effects of bottom-driven shear on the deformation of a brittle elastic-plastic layer with pseudo-three dimensional numerical models that include side forces. Strain localization results when the basal shear is a step-function while oblique-slip on numerous faults dominates when basal shear is distributed. We further investigate how the style of faulting varies with obliquity and demonstrate that the style of faulting observed in the Northern Gulf of California is reproduced in models with an obliquity of 0.7 and distributed basal shear boundary conditions, consistent with the interpreted obliquity and boundary conditions of the study area. Our

  7. Infrared MUSIC from Z technology focal planes

    International Nuclear Information System (INIS)

    Waters, C.R.; Sommese, A.; Johnston, D.; Landau, H.

    1989-01-01

    Presented is the Multiple Signal Classification (MUSIC) algorithm which uses the high frequency differences in sensed time signals to discriminate, count, and accurately locate closely spaced targets. Z technology focal planes allow the implementation of this algorithm and the trade-off between finer spatial resolution systems and systems with coarser resolution but higher sampling rates

  8. Focal dermal hypoplasia: A rare case report

    Directory of Open Access Journals (Sweden)

    Sahana M Srinivas

    2015-01-01

    Full Text Available Focal dermal hypoplasia (Goltz syndrome is a rare genetic multisystem disorder primarily involving the skin, skeletal system, eyes, and face. We report the case of an eight-month-old female child who presented with multiple hypopigmented atrophic macules along the lines of blaschko, skeletal anomalies, umbilical hernia, developmental delay, hypoplastic nails, syndactyly, and lobster claw deformity characteristic of Goltz syndrome.

  9. Reperfusion promotes mitochondrial dysfunction following focal cerebral ischemia in rats.

    Directory of Open Access Journals (Sweden)

    Jun Li

    Full Text Available BACKGROUND AND PURPOSE: Mitochondrial dysfunction has been implicated in the cell death observed after cerebral ischemia, and several mechanisms for this dysfunction have been proposed. Reperfusion after transient cerebral ischemia may cause continued and even more severe damage to the brain. Many lines of evidence have shown that mitochondria suffer severe damage in response to ischemic injury. The purpose of this study was to observe the features of mitochondrial dysfunction in isolated mitochondria during the reperfusion period following focal cerebral ischemia. METHODS: Male Wistar rats were subjected to focal cerebral ischemia. Mitochondria were isolated using Percoll density gradient centrifugation. The isolated mitochondria were fixed for electron microscopic examination; calcium-induced mitochondrial swelling was quantified using spectrophotometry. Cyclophilin D was detected by Western blotting. Fluorescent probes were used to selectively stain mitochondria to measure their membrane potential and to measure reactive oxidative species production using flow cytometric analysis. RESULTS: Signs of damage were observed in the mitochondrial morphology after exposure to reperfusion. The mitochondrial swelling induced by Ca(2+ increased gradually with the increasing calcium concentration, and this tendency was exacerbated as the reperfusion time was extended. Cyclophilin D protein expression peaked after 24 hours of reperfusion. The mitochondrial membrane potential was decreased significantly during the reperfusion period, with the greatest decrease observed after 24 hours of reperfusion. The surge in mitochondrial reactive oxidative species occurred after 2 hours of reperfusion and was maintained at a high level during the reperfusion period. CONCLUSIONS: Reperfusion following focal cerebral ischemia induced significant mitochondrial morphological damage and Ca(2+-induced mitochondrial swelling. The mechanism of this swelling may be mediated by

  10. ADAMTS9-Regulated Pericellular Matrix Dynamics Governs Focal Adhesion-Dependent Smooth Muscle Differentiation

    Directory of Open Access Journals (Sweden)

    Timothy J. Mead

    2018-04-01

    Full Text Available Summary: Focal adhesions anchor cells to extracellular matrix (ECM and direct assembly of a pre-stressed actin cytoskeleton. They act as a cellular sensor and regulator, linking ECM to the nucleus. Here, we identify proteolytic turnover of the anti-adhesive proteoglycan versican as a requirement for maintenance of smooth muscle cell (SMC focal adhesions. Using conditional deletion in mice, we show that ADAMTS9, a secreted metalloprotease, is required for myometrial activation during late gestation and for parturition. Through knockdown of ADAMTS9 in uterine SMC, and manipulation of pericellular versican via knockdown or proteolysis, we demonstrate that regulated pericellular matrix dynamics is essential for focal adhesion maintenance. By influencing focal adhesion formation, pericellular versican acts upstream of cytoskeletal assembly and SMC differentiation. Thus, pericellular versican proteolysis by ADAMTS9 balances pro- and anti-adhesive forces to maintain an SMC phenotype, providing a concrete example of the dynamic reciprocity of cells and their ECM. : Mead et al. identify a proteolytic mechanism that actively maintains a pericellular microenvironment conducive to uterine smooth muscle activation prior to parturition. They show that pericellular matrix proteolysis by the secreted metalloprotease ADAMTS9 is crucial for maintenance of focal adhesions in uterine smooth muscle cells, and its absence impairs parturition. Keywords: metalloprotease, extracellular matrix, smooth muscle, proteoglycan, myometrium, parturition, uterus, focal adhesion, proteolysis, interference reflection microscopy

  11. Determining the stress field in active volcanoes using focal mechanisms

    Directory of Open Access Journals (Sweden)

    Bruno Massa

    2016-11-01

    Full Text Available Stress inversion of seismological datasets became an essential tool to retrieve the stress field of active tectonics and volcanic areas. In particular, in volcanic areas, it is able to put constrains on volcano-tectonics and in general in a better understanding of the volcano dynamics. During the last decades, a wide range of stress inversion techniques has been proposed, some of them specifically conceived to manage seismological datasets. A modern technique of stress inversion, the BRTM, has been applied to seismological datasets available at three different regions of active volcanism: Mt. Somma-Vesuvius (197 Fault Plane Solutions, FPSs, Campi Flegrei (217 FPSs and Long Valley Caldera (38,000 FPSs. The key role of stress inversion techniques in the analysis of the volcano dynamics has been critically discussed. A particular emphasis was devoted to performances of the BRTM applied to volcanic areas.

  12. Radiopneumographic characteristics of focal pneumonia in children

    International Nuclear Information System (INIS)

    Smirnova, A.A.

    1980-01-01

    Zonal ventilation and blood flow were studied by the radiopneumography method in 50 children of school age with lower-lobe-of-the lung focal pneumonia (26 with left-side and 24 with right-side). It is established that during right-side localization of pneumonic focus preserved was the predomination of ventilation of right lung relative to left. Complete normalization of common and regional indexes of ventilation and blood flow was established by the 21st day from the beginning of treatment during right-side focal pneumonias. In case of left-side localization of pneumonic focus only partial reduction of external respiration and perfusion comes. Therefore, compensatory and reducing capabilities of right lung are preferrable

  13. Membership Functions for Fuzzy Focal Elements

    Directory of Open Access Journals (Sweden)

    Porębski Sebastian

    2016-09-01

    Full Text Available The paper presents a study on data-driven diagnostic rules, which are easy to interpret by human experts. To this end, the Dempster-Shafer theory extended for fuzzy focal elements is used. Premises of the rules (fuzzy focal elements are provided by membership functions which shapes are changing according to input symptoms. The main aim of the present study is to evaluate common membership function shapes and to introduce a rule elimination algorithm. Proposed methods are first illustrated with the popular Iris data set. Next experiments with five medical benchmark databases are performed. Results of the experiments show that various membership function shapes provide different inference efficiency but the extracted rule sets are close to each other. Thus indications for determining rules with possible heuristic interpretation can be formulated.

  14. Focal epilepsy in the Belgian shepherd

    DEFF Research Database (Denmark)

    Berendt, Mette; Gulløv, Christina Hedal; Fredholm, Merete

    2009-01-01

    and deceased) were ascertained through a telephone interview using a standardised questionnaire regarding seizure history and phenomenology. Living dogs were invited to a detailed clinical evaluation. Litters more than five years of age, or where epilepsy was present in all offspring before the age of five......, were included in the calculations of inheritance. results: Out of 199 family members, 66 dogs suffered from epilepsy. The prevalence of epilepsy in the family was 33%. Fifty-five dogs experienced focal seizures with or without secondary generalisation, while four dogs experienced primary generalised...... seizures. In seven dogs, seizures could not be classified. The mode of inheritance of epilepsy was simple Mendelian. CLINICAL SIGNIFICANCE: This study identified that the Belgian shepherd suffers from genetically transmitted focal epilepsy. The seizure phenomenology expressed by family members have...

  15. Chest pain in focal musculoskeletal disorders

    DEFF Research Database (Denmark)

    Stochkendahl, Mette Jensen; Christensen, Henrik Wulff

    2010-01-01

    overlapping conditions and syndromes of focal disorders, including Tietze syndrome, costochondritis, chest wall syndrome, muscle tenderness, slipping rib, cervical angina, and segmental dysfunction of the cervical and thoracic spine, have been reported to cause pain. For most of these syndromes, evidence......The musculoskeletal system is a recognized source of chest pain. However, despite the apparently benign origin, patients with musculoskeletal chest pain remain under-diagnosed, untreated, and potentially continuously disabled in terms of anxiety, depression, and activities of daily living. Several...... arises mainly from case stories and empiric knowledge. For segmental dysfunction, clinical features of musculoskeletal chest pain have been characterized in a few clinical trials. This article summarizes the most commonly encountered syndromes of focal musculoskeletal disorders in clinical practice....

  16. Characterization of LIL laser UV focal spot

    International Nuclear Information System (INIS)

    Mangeant, M.; Dubois, J.L.; Behar, G.; Arroyo, P.; Durand, V.; Lahonde, C.

    2006-01-01

    One way to get the fusion of hydrogen in laboratory consists in heating and compressing a DT fuel capsule by using a laser. To reach this aim requires a new generation of high power laser facility. Cea (French board for atomic energy) is developing for this purpose a new 240 laser line facility, the LMJ facility. The LIL which is the prototype of four LMJ laser lines is operational now. In order to confirm the technical choices, a systematic characterization of LIL was carried out. A particular effort has been provided to measure the 3ω high energy focal spot (1.5 kJ/700 ps and 5 ns for one beam) and the synchronization of laser beams onto the target, which are key issues for the plasma production. An experimental device, SAT-3ω (a 3ω laser focal spot analysis) has been designed to perform these measures. That diagnostic which is located at the end of the laser lines delivered its first results during the 2004 quadruplet qualification campaigns. The near field imaging showed no diaphony and vignetting. Low power spots allowed us to control we had no ghost. The energy measurement quality showed the photometric transfer function was perfectly known. Our caustic image are given with an average dynamic range of 800, a spatial resolution of 10 μm and diameter accuracy about 1% for 50% and 3% for 90% of encircled energy. The high energy focal spot diameters are in agreement with low and very low energy diameters. The phase plate and 14 GHz effects are similar to what we had expected. For a laser shot completed with a continuous phase plate at 14 GHz, and for an energy level of 1.5 kJ per beam at 351 nm, the focal beam diameter at 3% of the peak level is (875 ± 45) μm

  17. Proximal focal femoral deficiency: A case report

    Directory of Open Access Journals (Sweden)

    Shashank Sharma

    2015-01-01

    Full Text Available Proximal focal femoral deficiency (PFFD is a rare congenital anomaly resulting in limb shortening and disability in young. The exact cause of the disease is not known and it may present as varying grades of affection involving the proximal femur and the acetabulum. Recognition of this rare abnormality on radiographs can help manage these cases better since early institution of therapy may help in achieving adequate growth of the femur.

  18. Syndecan-4 and focal adhesion function

    DEFF Research Database (Denmark)

    Woods, A; Couchman, J R

    2001-01-01

    Two groups have now reported the viability of mice that lack syndecan-4. These mice have wound healing/angiogenesis problems, and fibroblasts from these animals differ in adhesion and migration from normal. This is consistent with recent in vitro data indicating a need for signaling via syndecan-4...... for focal adhesion formation, and reports that overexpression of proteins that bind syndecan-4 can modify cell adhesion and migration....

  19. Focal plane scanner with reciprocating spatial window

    Science.gov (United States)

    Mao, Chengye (Inventor)

    2000-01-01

    A focal plane scanner having a front objective lens, a spatial window for selectively passing a portion of the image therethrough, and a CCD array for receiving the passed portion of the image. All embodiments have a common feature whereby the spatial window and CCD array are mounted for simultaneous relative reciprocating movement with respect to the front objective lens, and the spatial window is mounted within the focal plane of the front objective. In a first embodiment, the spatial window is a slit and the CCD array is one-dimensional, and successive rows of the image in the focal plane of the front objective lens are passed to the CCD array by an image relay lens interposed between the slit and the CCD array. In a second embodiment, the spatial window is a slit, the CCD array is two-dimensional, and a prism-grating-prism optical spectrometer is interposed between the slit and the CCD array so as to cause the scanned row to be split into a plurality of spectral separations onto the CCD array. In a third embodiment, the CCD array is two-dimensional and the spatial window is a rectangular linear variable filter (LVF) window, so as to cause the scanned rows impinging on the LVF to be bandpass filtered into spectral components onto the CCD array through an image relay lens interposed between the LVF and the CCD array.

  20. Fethiye-Burdur Fault Zone (SW Turkey): a myth?

    Science.gov (United States)

    Kaymakci, Nuretdin; Langereis, Cornelis; Özkaptan, Murat; Özacar, Arda A.; Gülyüz, Erhan; Uzel, Bora; Sözbilir, Hasan

    2017-04-01

    Fethiye Burdur Fault Zone (FBFZ) is first proposed by Dumont et al. (1979) as a sinistral strike-slip fault zone as the NE continuation of Pliny-Strabo trench in to the Anatolian Block. The fault zone supposed to accommodate at least 100 km sinistral displacement between the Menderes Massif and the Beydaǧları platform during the exhumation of the Menderes Massif, mainly during the late Miocene. Based on GPS velocities Barka and Reilinger (1997) proposed that the fault zone is still active and accommodates sinistral displacement. In order to test the presence and to unravel its kinematics we have conducted a rigorous paleomagnetic study containing more than 3000 paleomagnetic samples collected from 88 locations and 11700 fault slip data collected from 198 locations distributed evenly all over SW Anatolia spanning from Middle Miocene to Late Pliocene. The obtained rotation senses and amounts indicate slight (around 20°) counter-clockwise rotations distributed uniformly almost whole SW Anatolia and there is no change in the rotation senses and amounts on either side of the FBFZ implying no differential rotation within the zone. Additionally, the slickenside pitches and constructed paleostress configurations, along the so called FBFZ and also within the 300 km diameter of the proposed fault zone, indicated that almost all the faults, oriented parallel to subparallel to the zone, are normal in character. The fault slip measurements are also consistent with earthquake focal mechanisms suggesting active extension in the region. We have not encountered any significant strike-slip motion in the region to support presence and transcurrent nature of the FBFZ. On the contrary, the region is dominated by extensional deformation and strike-slip components are observed only on the NW-SE striking faults which are transfer faults that accommodated extension and normal motion. Therefore, we claim that the sinistral Fethiye Burdur Fault (Zone) is a myth and there is no tangible

  1. Subduction and vertical coastal motions in the eastern Mediterranean

    Science.gov (United States)

    Howell, Andy; Jackson, James; Copley, Alex; McKenzie, Dan; Nissen, Ed

    2017-10-01

    Convergence in the eastern Mediterranean of oceanic Nubia with Anatolia and the Aegean is complex and poorly understood. Large volumes of sediment obscure the shallow structure of the subduction zone, and since much of the convergence is accommodated aseismically, there are limited earthquake data to constrain its kinematics. We present new source models for recent earthquakes, combining these with field observations, published GPS velocities and reflection-seismic data to investigate faulting in three areas: the Florence Rise, SW Turkey and the Pliny and Strabo Trenches. The depths and locations of earthquakes reveal the geometry of the subducting Nubian plate NE of the Florence Rise, a bathymetric high that is probably formed by deformation of sediment at the surface projection of the Anatolia-Nubia subduction interface. In SW Turkey, the presence of a strike-slip shear zone has often been inferred despite an absence of strike-slip earthquakes. We show that the GPS-derived strain-rate field is consistent with extension on the orthogonal systems of normal faults observed in the region and that strike-slip faulting is not required to explain observed GPS velocities. Further SW, the Pliny and Strabo Trenches are also often interpreted as strike-slip shear zones, but almost all nearby earthquakes have either reverse-faulting or normal-faulting focal mechanisms. Oblique convergence across the trenches may be accommodated either by a partitioned system of strike-slip and reverse faults or by oblique slip on the Aegean-Nubia subduction interface. The observed late-Quaternary vertical motions of coastlines close to the subduction zone are influenced by the interplay between: (1) thickening of the material overriding the subduction interface associated with convergence, which promotes coastal uplift; and (2) subsidence due to extension and associated crustal thinning. Long-wavelength gravity data suggest that some of the observed topographic contrasts in the eastern

  2. Classification of Focal and Non Focal Epileptic Seizures Using Multi-Features and SVM Classifier.

    Science.gov (United States)

    Sriraam, N; Raghu, S

    2017-09-02

    Identifying epileptogenic zones prior to surgery is an essential and crucial step in treating patients having pharmacoresistant focal epilepsy. Electroencephalogram (EEG) is a significant measurement benchmark to assess patients suffering from epilepsy. This paper investigates the application of multi-features derived from different domains to recognize the focal and non focal epileptic seizures obtained from pharmacoresistant focal epilepsy patients from Bern Barcelona database. From the dataset, five different classification tasks were formed. Total 26 features were extracted from focal and non focal EEG. Significant features were selected using Wilcoxon rank sum test by setting p-value (p z > 1.96) at 95% significance interval. Hypothesis was made that the effect of removing outliers improves the classification accuracy. Turkey's range test was adopted for pruning outliers from feature set. Finally, 21 features were classified using optimized support vector machine (SVM) classifier with 10-fold cross validation. Bayesian optimization technique was adopted to minimize the cross-validation loss. From the simulation results, it was inferred that the highest sensitivity, specificity, and classification accuracy of 94.56%, 89.74%, and 92.15% achieved respectively and found to be better than the state-of-the-art approaches. Further, it was observed that the classification accuracy improved from 80.2% with outliers to 92.15% without outliers. The classifier performance metrics ensures the suitability of the proposed multi-features with optimized SVM classifier. It can be concluded that the proposed approach can be applied for recognition of focal EEG signals to localize epileptogenic zones.

  3. VERIFICATION OF THE SENTINEL-4 FOCAL PLANE SUBSYSTEM

    Directory of Open Access Journals (Sweden)

    C. Williges

    2017-05-01

    Full Text Available The Sentinel-4 payload is a multi-spectral camera system which is designed to monitor atmospheric conditions over Europe. The German Aerospace Center (DLR in Berlin, Germany conducted the verification campaign of the Focal Plane Subsystem (FPS on behalf of Airbus Defense and Space GmbH, Ottobrunn, Germany. The FPS consists, inter alia, of two Focal Plane Assemblies (FPAs, one for the UV-VIS spectral range (305 nm … 500 nm, the second for NIR (750 nm … 775 nm. In this publication, we will present in detail the opto-mechanical laboratory set-up of the verification campaign of the Sentinel-4 Qualification Model (QM which will also be used for the upcoming Flight Model (FM verification. The test campaign consists mainly of radiometric tests performed with an integrating sphere as homogenous light source. The FPAs have mainly to be operated at 215 K ± 5 K, making it necessary to exploit a thermal vacuum chamber (TVC for the test accomplishment. This publication focuses on the challenge to remotely illuminate both Sentinel-4 detectors as well as a reference detector homogeneously over a distance of approximately 1 m from outside the TVC. Furthermore selected test analyses and results will be presented, showing that the Sentinel-4 FPS meets specifications.

  4. The Simbol-X Focal Plane

    Science.gov (United States)

    Laurent, P.

    2009-05-01

    The Simbol-X focal plane is designed to detect photons focused by the mirror in the 0.5 to 100 keV energy band. Composed of two detectors, it will measure the position, energy, and arrival time of each incoming X-ray. On top of it will be a collimator to shield all photons not coming from the mirror field of view. The whole system is surrounded by an active and passive shielding in order to ensure the required very low background.

  5. Focal inflammatory diseases of the liver

    International Nuclear Information System (INIS)

    Oto, Aytekin; Akhan, Okan; Oezmen, Mustafa

    1999-01-01

    Inflammatory lesions constitute an important subgroup of focal liver lesions. They may mimic primary or metastatic neoplastic lesions and their differentiation from neoplasia is clinically very important since management of the patient significantly changes. Radiologists should have an important role in both the diagnosis and therapy of these lesions by performing percutaneous aspirations and drainages. In this review we discussed the radiological findings of pyogenic abscesses, amebic abscesses, candidiasis, tuberculosis, hydatic cysts, fascioliasis, ascariasis, schistosomiasis, and sarcoidosis with a special emphasis on US, CT and MR characteristics

  6. Focal inflammatory diseases of the liver

    Energy Technology Data Exchange (ETDEWEB)

    Oto, Aytekin; Akhan, Okan; Oezmen, Mustafa

    1999-10-01

    Inflammatory lesions constitute an important subgroup of focal liver lesions. They may mimic primary or metastatic neoplastic lesions and their differentiation from neoplasia is clinically very important since management of the patient significantly changes. Radiologists should have an important role in both the diagnosis and therapy of these lesions by performing percutaneous aspirations and drainages. In this review we discussed the radiological findings of pyogenic abscesses, amebic abscesses, candidiasis, tuberculosis, hydatic cysts, fascioliasis, ascariasis, schistosomiasis, and sarcoidosis with a special emphasis on US, CT and MR characteristics.

  7. Characterization of DECam focal plane detectors

    Energy Technology Data Exchange (ETDEWEB)

    Diehl, H.Thomas; Angstadt, Robert; Campa, Julia; Cease, Herman; Derylo, Greg; Emes, John H.; Estrada, Juan; Kibik, Donna; Flaugher, Brenna L.; Holland, Steve E.; Jonas, Michelle; /Fermilab /Madrid, CIEMAT /LBL, Berkeley /Argonne /Pennsylvania U.

    2008-06-01

    DECam is a 520 Mpix, 3 square-deg FOV imager being built for the Blanco 4m Telescope at CTIO. This facility instrument will be used for the 'Dark Energy Survey' of the southern galactic cap. DECam has chosen 250 ?m thick CCDs, developed at LBNL, with good QE in the near IR for the focal plane. In this work we present the characterization of these detectors done by the DES team, and compare it to the DECam technical requirements. The results demonstrate that the detectors satisfy the needs for instrument.

  8. Plate boundary deformation of the Pacific plate. Two case studies. (1) Crustal structure of the northwestern Vizcaino block and Gorda escarpment, offshore northern California, and implications for postsubduction deformation of a paleoaccretionary margin. (2) A focused look at the Alpine fault, New Zealand: Seismicity, focal mechanisms and stress observations

    Science.gov (United States)

    Leitner, Beate

    Two examples of Pacific rim plate boundary deformation are presented. In the first part of the thesis crustal models are derived for the northwestern part of the Vizcaino block in California using marine seismic and gravity data collected by the Mendocino Triple Junction Seismic Experiment. A northwest-southeast trending kink in the Moho is imaged and interpreted to have formed under compression by reactivation of preexisting thrust faults in the paleoaccretionary prism at the seaward margin of the Vizcaino block. The study suggests that the deformation resulted from mainly north-south compression between the Pacific-Juan de Fuca plates across the Mendocino transform fault and predates late Pliocene Pacific-North America plate convergence. In the second part, 195 earthquakes recorded during the duration of the Southern Alps Passive Seismic Experiment (SAPSE) are analysed. Precise earthquake locations and focal mechanisms provide unprecedented detail of the seismotectonics in the central South Island. The short term (6 month) SAPSE seismicity is compared with long term (8 years) seismicity recorded by the New Zealand National Seismic network and the Lake Pukaki network. The seismicity rate of the Alpine fault is low, but comparable to locked sections of the San Andreas fault, with large earthquakes expected. Changes of the depth of the seismogenic zone, generally uniform at about 10--12 km, occur only localised over distances smaller than 30 km, suggesting that thermal perturbations must be of similar scale. This implies that the thermal effects of the uplift of the Southern Alps do not change the seismogenic depth significantly and are not in accordance with most of the present thermal models. Both the Hope and Porters Pass fault zones are seismically active and deformation is accommodated near the fault zones and in the adjacent crust. North of Mt Cook, a triangular shaped region along the Alpine fault is characterised by absence of earthquakes. We interpret this

  9. Mechanics

    CERN Document Server

    Hartog, J P Den

    1961-01-01

    First published over 40 years ago, this work has achieved the status of a classic among introductory texts on mechanics. Den Hartog is known for his lively, discursive and often witty presentations of all the fundamental material of both statics and dynamics (and considerable more advanced material) in new, original ways that provide students with insights into mechanical relationships that other books do not always succeed in conveying. On the other hand, the work is so replete with engineering applications and actual design problems that it is as valuable as a reference to the practicing e

  10. Focal Targeting of the Bacterial Envelope by Antimicrobial Peptides

    Directory of Open Access Journals (Sweden)

    Rafi eRashid

    2016-06-01

    Full Text Available Antimicrobial peptides (AMPs are utilized by both eukaryotic and prokaryotic organisms. AMPs such as the human beta defensins, human neutrophil peptides, human cathelicidin, and many bacterial bacteriocins are cationic and capable of binding to anionic regions of the bacterial surface. Cationic AMPs (CAMPs target anionic lipids (e.g. phosphatidylglycerol (PG and cardiolipins (CL in the cell membrane and anionic components (e.g. lipopolysaccharide (LPS and lipoteichoic acid (LTA of the cell envelope. Bacteria have evolved mechanisms to modify these same targets in order to resist CAMP killing, e.g. lysinylation of PG to yield cationic lysyl-PG and alanylation of LTA. Since CAMPs offer a promising therapeutic alternative to conventional antibiotics, which are becoming less effective due to rapidly emerging antibiotic resistance, there is a strong need to improve our understanding about the AMP mechanism of action. Recent literature suggests that AMPs often interact with the bacterial cell envelope at discrete foci. Here we review recent AMP literature, with an emphasis on focal interactions with bacteria, including (1 CAMP disruption mechanisms, (2 delocalization of membrane proteins and lipids by CAMPs, and (3 CAMP sensing systems and resistance mechanisms. We conclude with new approaches for studying the bacterial membrane, e.g., lipidomics, high resolution imaging and non-detergent-based membrane domain extraction.

  11. Laparoscopic Partial Hepatectomy of Focal Nodular Hyperplasia

    Directory of Open Access Journals (Sweden)

    Mayu Sakata

    2012-11-01

    Full Text Available Focal nodular hyperplasia is a benign liver lesion incidentally discovered with increasing frequency because of the proliferation of imaging studies. Radiographic characterization can diagnose this pathologic lesion and nonoperative therapy is the standard of care. However, surgical resection may be required for diagnostic reasons or symptomatic patients. Depending on the anatomic location of the lesion, biopsy and/or resection can be performed laparoscopically. We herein report the case of a 26-year-old Japanese woman with a hepatic tumor who required a medical examination. Her medical history was negative for alcohol abuse, oral contraceptive administration and trauma. Clinical examination showed no significant symptoms. Ultrasonography, computed tomography and magnetic resonance imaging showed a mass located in the left lateral segment of the liver with a diameter of about 40 mm. It was difficult to diagnose the tumor definitively from these imaging studies, so we performed laparoscopic partial hepatectomy with successive firing of endoscopic staplers. The histopathological diagnosis was focal nodular hyperplasia. Surgical procedures and postoperative course were uneventful and the patient was discharged from the hospital on postoperative day 5.

  12. CT scan findings in focal epilepsy

    International Nuclear Information System (INIS)

    Kobayashi, Eiki; Mihara, Tadahiro; Yamamoto, Kunimitsu; Yamashita, Kenji; Asakura, Tetsuhiko

    1980-01-01

    In 80 cases of focal epilepsy, excluding such cases as late onset after the age of 30 and traumatic or expansive lesions, the epileptogenic foci have been studied by comparing the CT findings with the seizure types and the EEG findings. The results were as follows: (1) Abnormal CT findings were observed in 36% of the patients. (2) These findings were classified into 4 large groups: localized cerebral atrophy, localized low density, localized high density with contrast enhancement and diffuse cerebral atrophy. (3) The incidence of CT abnormality was higher in the cases with continuous and localized EEG abnormality than in the cases with other types of EEG abnormality. In 48% of the cases, the location of the abnormal CT findings coincided with their EEG foci. (4) In the cases of temporal lobe epilepsy without abnormal CT images, the print-out data compared with the bilateral promised temporal regions, before and after contrast enhancement. The EMI-No. of the medial temporal focus increased more than that of the contralateral side in 3 cases out of 4 after contrast-media injection. (5) Moreover, for the purpose of comparing the CT findings on general seizures with those in focal seizures, we have studied 80 cases of general seizures. In the cases of the general seizures, abnormal CT findings were observed in only 16%. These abnormal findings were diffuse in 5 cases, localized in 6 cases, and combined in 3 cases. (author)

  13. The Sentinel 4 focal plane subsystem

    Science.gov (United States)

    Hohn, Rüdiger; Skegg, Michael P.; Hermsen, Markus; Hinger, Jürgen; Williges, Christian; Reulke, Ralf

    2017-09-01

    The Sentinel 4 instrument is an imaging spectrometer, developed by Airbus under ESA contract in the frame of the joint European Union (EU)/ESA COPERNICUS program with the objective of monitoring trace gas concentrations. Sentinel 4 will provide accurate measurements of key atmospheric constituents such as ozone, nitrogen dioxide, sulfur dioxide, formaldehyde, as well as aerosol and cloud properties. Sentinel 4 is unique in being the first geostationary UVN mission. The SENTINEL 4 space segment will be integrated on EUMETSAT's Meteosat Third Generation Sounder satellite (MTG-S). Sentinel 4 will provide coverage of Europe and adjacent regions. The Sentinel 4 instrument comprises as a major element two Focal Plane Subsystems (FPS) covering the wavelength ranges 305 nm to 500 nm (UVVIS) and 750 nm to 775 nm (NIR) respectively. The paper describes the Focal Plane Subsystems, comprising the detectors, the optical bench and the control electronics. Further the design and development approach will be presented as well as first measurement results of FPS Qualification Model.

  14. Focal CT abnormality and epileptogenic focus

    International Nuclear Information System (INIS)

    Yagi, Kazuichi; Mihara, Tadahiro; Tottori, Takayasu; Matsuda, Kazumi; Watanabe, Yutaka; Seino, Masakazu

    1989-01-01

    In 31 patients with temporal lobe epilepsy, the precise site of epileptogenic focus was determined by means of a depth EEG recording as one of the presurgical evaluations. In 13 patients, a CT scan revealed focal lesions; 7 in the left temporal lobe and 6 in the right temporal lobe. In 5 of the 7 patients and in 5 of the 6 patients the epileptogenic foci were determined in the temporal lobe on the side of a CT lesion. However, in 2 of the patients with a CT lesion in the left temporal lobe, independent epileptogenic foci were found in both the temporal lobes, and in the other patient with a CT lesion in the right temporal lobe, they were found in the right frontal and left temporal lobes. Thus, the CT lesions agreed in lateralization and focality with the epileptogenic foci in 10 of the 13 patients (77%), but they disagreed in 3 (23%). A CT lesion disclosed in the temporal lobe does not necessarily indicate the side and/or site where the epileptogenic focus may be localized. Although exceptions may be made, spatial disagreement was exemplified between the CT lesion and epileptogenic focus. Therefore, extreme caution has to be taken on the side and/or site of the epileptogenic focus when functional surgical indication is to be made. (author)

  15. Focal fatty infiltra- tion and focal fatty sparing of the liver

    African Journals Online (AJOL)

    Enrique

    Department of Radiology. Nelson Mandela School of Health Sciences. Durban. Fig. 1a. Unenhanced CT of the liver in case 1 demonstrates multiple focal low density regions in both lobes of the liver. Region of interest 1 over the fatty left lobe measured 10 HU while region of interest 2 over the right lobe measure 40 HU in.

  16. CT appearance of focal fatty infiltration of the liver

    International Nuclear Information System (INIS)

    Halvorsen, R.A.; Korobkin, M.; Ram, P.C.; Thompson, W.M.

    1982-01-01

    Focal fatty infiltration of the liver is an entity that may be confused with liver metastasis on computed tomography (CT). The imaging results and medical records of 16 patients with CT appearance suggestive of focal fatty liver were reviewed, three of whom had the simultaneous presence of metastitic liver disease. Focal fatty liver often has a distinctive appearance with CT, usually with a nonspherical shape, absence of mass effect, and density close to water. Liver metastases are usually round or oval, and unless cystic or necrotic, they have CT attenuation values closer to normal liver parenchyma than water. A radionuclide liver scan almost always resolves any confusion about the differential diagnosis of focal fatty liver: a well defined focus of photon deficiency is due to neoplasm rather than focal fatty infiltration. Sonography sometimes helps to confirm the CT impression, but may be misleading if the diagnosis of focal or diffuse fatty infiltration is not suspected before the examination

  17. The study of the focal trough in panoramic radiograph

    International Nuclear Information System (INIS)

    Park, C. S.; Kim, H. P.

    1982-01-01

    In the study of the focal trough of panoramic radiograph, using the Moritta company Panex EC a series of 48 exposures were taken with the 6-18 brass pins placed in the holes of the plastic model plate, then evaluated by 4 observers. The author analyzed the focal trough defined by the sharpness criteria and calculated the vertical and horizontal magnification range in the corrected focal trough. The results were as follows; 1. Continuous focal trough was not defined in the anterior region using a very high degree of sharpness. 2. As degree of sharpness used in the analysis became less, focal trough was continuous in the anterior and posterior regions, symmetrized bilaterally, and the widths of the focal trough increased more in the posterior region. 3. As sharpness criteria were reduced, the percentage range of image magnification increased in both vertical and horizontal magnification, and especially the percentage range of horizontal magnification was greater than that of vertical magnification.

  18. Multi-focal Vision and Gaze Control Improve Navigation Performance

    Directory of Open Access Journals (Sweden)

    Kolja Kuehnlenz

    2008-11-01

    Full Text Available Multi-focal vision systems comprise cameras with various fields of view and measurement accuracies. This article presents a multi-focal approach to localization and mapping of mobile robots with active vision. An implementation of the novel concept is done considering a humanoid robot navigation scenario where the robot is visually guided through a structured environment with several landmarks. Various embodiments of multi-focal vision systems are investigated and the impact on navigation performance is evaluated in comparison to a conventional mono-focal stereo set-up. The comparative studies clearly show the benefits of multi-focal vision for mobile robot navigation: flexibility to assign the different available sensors optimally in each situation, enhancement of the visible field, higher localization accuracy, and, thus, better task performance, i.e. path following behavior of the mobile robot. It is shown that multi-focal vision may strongly improve navigation performance.

  19. Focal cemento-osseous dysplasia of mandible.

    Science.gov (United States)

    Cankaya, Abdülkadir Burak; Erdem, Mehmet Ali; Olgac, Vakur; Firat, Deniz Refia

    2012-09-03

    Fibro-osseous lesions are disturbances in bone metabolism in which normal bone is replaced by a connective tissue matrix that then gradually develops into cemento-osseous tissue. Typically, the lesion is asymptomatic and is detected on routine radiographic examination. Radiologically, this lesion has three stages of maturation: pure radiolucent, radiopaque/mixed radiolucent, and radiopaque appearance. During these stages the lesion can be misdiagnosed. In this case report a 69-year- old patient with a a complaint of painless swelling of the left mandibular molar and premolar area is presented along with a review of the differential diagnoses considered in order to reach a final diagnosis of focal cemento-osseous dysplasia.

  20. Strong reducing of the laser focal volume

    CSIR Research Space (South Africa)

    Godin, T

    2011-08-01

    Full Text Available equal to -1 or +1 modeled on the p light rings of the incident TEMp0 beam. The transformation quality of a 30TEM beam into a single-lobed pattern in the focal plane is shown in Fig. 3. It is clear that the intensity pattern of the rectified beam... DOE (blue solid line), rectified 30TEM (red solid line) -3 -2 -1 0 1 2 3 0 1 2 3 4 z=0 z=f DOE Fig. 2 -60 -50 -40 -30 -20 -10 0 10 20 30 40 50 60 0,0 0,2 0,4 0,6 0,8 1,0 TEM30 without DOE "rectified" TEM30 TEM00 In te ns...

  1. Smart trigger logic for focal plane arrays

    Science.gov (United States)

    Levy, James E; Campbell, David V; Holmes, Michael L; Lovejoy, Robert; Wojciechowski, Kenneth; Kay, Randolph R; Cavanaugh, William S; Gurrieri, Thomas M

    2014-03-25

    An electronic device includes a memory configured to receive data representing light intensity values from pixels in a focal plane array and a processor that analyzes the received data to determine which light values correspond to triggered pixels, where the triggered pixels are those pixels that meet a predefined set of criteria, and determines, for each triggered pixel, a set of neighbor pixels for which light intensity values are to be stored. The electronic device also includes a buffer that temporarily stores light intensity values for at least one previously processed row of pixels, so that when a triggered pixel is identified in a current row, light intensity values for the neighbor pixels in the previously processed row and for the triggered pixel are persistently stored, as well as a data transmitter that transmits the persistently stored light intensity values for the triggered and neighbor pixels to a data receiver.

  2. Pharmacological response of systemically derived focal epileptic lesions

    Energy Technology Data Exchange (ETDEWEB)

    Remler, M.P.; Sigvardt, K.; Marcussen, W.H.

    1986-11-01

    Focal epileptic lesions were made in rats by systemic focal epileptogenesis. In this method, a focal lesion of the blood-brain barrier (BBB) is produced by focal alpha irradiation followed by repeated systemic injection of a convulsant drug that cannot cross the normal BBB, resulting in a chronic epileptic focus. Changes in the spike frequency of these foci in response to various drugs was recorded. The controls, saline and chlorpromazine, produced no change. Phenytoin, phenobarbital, chlordiazepoxide, and valproic acid produced the expected decrease in spike frequency. Pentobarbital and diazepam produced a paradoxical increase in spike frequency.

  3. Focal cryotherapy: step by step technique description

    Directory of Open Access Journals (Sweden)

    Cristina Redondo

    Full Text Available ABSTRACT Introduction and objective: Focal cryotherapy emerged as an efficient option to treat favorable and localized prostate cancer (PCa. The purpose of this video is to describe the procedure step by step. Materials and methods: We present the case of a 68 year-old man with localized PCa in the anterior aspect of the prostate. Results: The procedure is performed under general anesthesia, with the patient in lithotomy position. Briefly, the equipment utilized includes the cryotherapy console coupled with an ultrasound system, argon and helium gas bottles, cryoprobes, temperature probes and an urethral warming catheter. The procedure starts with a real-time trans-rectal prostate ultrasound, which is used to outline the prostate, the urethra and the rectal wall. The cryoprobes are pretested and placed in to the prostate through the perineum, following a grid template, along with the temperature sensors under ultrasound guidance. A cystoscopy confirms the right positioning of the needles and the urethral warming catheter is installed. Thereafter, the freeze sequence with argon gas is started, achieving extremely low temperatures (-40°C to induce tumor cell lysis. Sequentially, the thawing cycle is performed using helium gas. This process is repeated one time. Results among several series showed a biochemical disease-free survival between 71-93% at 9-70 month- follow-up, incontinence rates between 0-3.6% and erectile dysfunction between 0-42% (1–5. Conclusions: Focal cryotherapy is a feasible procedure to treat anterior PCa that may offer minimal morbidity, allowing good cancer control and better functional outcomes when compared to whole-gland treatment.

  4. Sighting optics including an optical element having a first focal length and a second focal length and methods for sighting

    Science.gov (United States)

    Crandall, David Lynn

    2011-08-16

    Sighting optics include a front sight and a rear sight positioned in a spaced-apart relation. The rear sight includes an optical element having a first focal length and a second focal length. The first focal length is selected so that it is about equal to a distance separating the optical element and the front sight and the second focal length is selected so that it is about equal to a target distance. The optical element thus brings into simultaneous focus for a user images of the front sight and the target.

  5. Seismogeodesy of the 2014 Mw6.1 Napa earthquake, California: Rapid response and modeling of fast rupture on a dipping strike-slip fault

    Science.gov (United States)

    Melgar, Diego; Geng, Jianghui; Crowell, Brendan W.; Haase, Jennifer S.; Bock, Yehuda; Hammond, William C.; Allen, Richard M.

    2015-07-01

    Real-time high-rate geodetic data have been shown to be useful for rapid earthquake response systems during medium to large events. The 2014 Mw6.1 Napa, California earthquake is important because it provides an opportunity to study an event at the lower threshold of what can be detected with GPS. We show the results of GPS-only earthquake source products such as peak ground displacement magnitude scaling, centroid moment tensor (CMT) solution, and static slip inversion. We also highlight the retrospective real-time combination of GPS and strong motion data to produce seismogeodetic waveforms that have higher precision and longer period information than GPS-only or seismic-only measurements of ground motion. We show their utility for rapid kinematic slip inversion and conclude that it would have been possible, with current real-time infrastructure, to determine the basic features of the earthquake source. We supplement the analysis with strong motion data collected close to the source to obtain an improved postevent image of the source process. The model reveals unilateral fast propagation of slip to the north of the hypocenter with a delayed onset of shallow slip. The source model suggests that the multiple strands of observed surface rupture are controlled by the shallow soft sediments of Napa Valley and do not necessarily represent the intersection of the main faulting surface and the free surface. We conclude that the main dislocation plane is westward dipping and should intersect the surface to the east, either where the easternmost strand of surface rupture is observed or at the location where the West Napa fault has been mapped in the past.

  6. Mesozoic strike-slip movement of the Dunhua-Mishan Fault Zone in NE China: A response to oceanic plate subduction

    Science.gov (United States)

    Liu, Cheng; Zhu, Guang; Zhang, Shuai; Gu, Chengchuan; Li, Yunjian; Su, Nan; Xiao, Shiye

    2018-01-01

    The NE-striking Dunhua-Mishan Fault Zone (DMFZ) is one of two branches of the continental-scale sinistral Tan-Lu Fault Zone in NE China. The field data presented here indicate that the ca. 1000 km long DMFZ records two phases of sinistral faulting. The structures produced by these two phases of faulting include NE-SW-striking ductile shear belts and brittle faults, respectively. Mylonite-hosted microstructures and quartz c-axis fabrics suggest deformation temperatures of 450 °C-500 °C for the ductile shear belts. Combining new zircon U-Pb dates for 14 igneous rock samples analyzed during this study with the geology of this region indicates these shear belts formed during the earliest Early Cretaceous. This phase of sinistral displacement represents the initial formation of the DMFZ in response to the northward propagation of the Tan-Lu Fault Zone into NE China. A phase of Early Cretaceous rifting was followed by a second phase of sinistral faulting at 102-96 Ma, as evidenced by our new U-Pb ages for associated igneous rocks. Combining our new data with the results of previous research indicates that the DFMZ records a four-stage Cretaceous evolutionary history, where initial sinistral faulting at the beginning of the Early Cretaceous gave way to rifting during the rest of the Early Cretaceous. This was followed by a second phase of sinistral faulting at the beginning of the Late Cretaceous and a second phase of local rifting during the rest of the Late Cretaceous. The Cretaceous evolution of the DMFZ records the synchronous tectonic evolution of the NE China continent bordering the Pacific Ocean. Two phases of regional N-S compression generated the two phases of sinistral faulting within the DMFZ, whereas two-stage regional extension generated the two phases of rifting. The two compressive events were the result of the rapid low-angle subduction of the Izanagi and Pacific plates, whereas the two-stage extension was caused by the roll-back of these respective plates. The final closure of the Mongol-Okhotsk Ocean at the beginning of the Early Cretaceous intensified the synchronous compression in NE China, causing the northward propagation of the Tan-Lu Fault Zone.

  7. SHRIMP U-Pb zircon dating of Archean core complex formatio and pancratonic strike-slip deformation in the East Pilbara Granite-Greenstone Terrain

    NARCIS (Netherlands)

    Zegers, T.E.; Nelson, D.R.; Wijbrans, J.R.; White, S.H.

    2001-01-01

    Sensitive high-resolution ion microprobe (SHRIMP) U-Pb dating of zircons from granitic rocks in the East Pilbara Granite-Greenstone Terrain has provided time constraints for main tectonic events in the Shaw Granitoid Complex and has shown that deformation was intricately related to granitoid

  8. Empirical Relationships Among Magnitude and Surface Rupture Characteristics of Strike-Slip Faults: Effect of Fault (System) Geometry and Observation Location, Dervided From Numerical Modeling

    Science.gov (United States)

    Zielke, O.; Arrowsmith, J.

    2007-12-01

    In order to determine the magnitude of pre-historic earthquakes, surface rupture length, average and maximum surface displacement are utilized, assuming that an earthquake of a specific size will cause surface features of correlated size. The well known Wells and Coppersmith (1994) paper and other studies defined empirical relationships between these and other parameters, based on historic events with independently known magnitude and rupture characteristics. However, these relationships show relatively large standard deviations and they are based only on a small number of events. To improve these first-order empirical relationships, the observation location relative to the rupture extent within the regional tectonic framework should be accounted for. This however cannot be done based on natural seismicity because of the limited size of datasets on large earthquakes. We have developed the numerical model FIMozFric, based on derivations by Okada (1992) to create synthetic seismic records for a given fault or fault system under the influence of either slip- or stress boundary conditions. Our model features A) the introduction of an upper and lower aseismic zone, B) a simple Coulomb friction law, C) bulk parameters simulating fault heterogeneity, and D) a fault interaction algorithm handling the large number of fault patches (typically 5,000-10,000). The joint implementation of these features produces well behaved synthetic seismic catalogs and realistic relationships among magnitude and surface rupture characteristics which are well within the error of the results by Wells and Coppersmith (1994). Furthermore, we use the synthetic seismic records to show that the relationships between magntiude and rupture characteristics are a function of the observation location within the regional tectonic framework. The model presented here can to provide paleoseismologists with a tool to improve magnitude estimates from surface rupture characteristics, by incorporating the regional and local structural context which can be determined in the field: Assuming a paleoseismologist measures the offset along a fault caused by an earthquake, our model can be used to determine the probability distribution of magnitudes which are capable of producing the observed offset, accounting for regional tectonic setting and observation location.

  9. Structure of the la VELA Offshore Basin, Western Venezuela: AN Obliquely-Opening Rift Basin Within the South America-Caribbean Strike-Slip Plate Boundary

    Science.gov (United States)

    Blanco, J. M.; Mann, P.

    2015-12-01

    Bathymetric, gravity and magnetic maps show that the east-west trend of the Cretaceous Great Arc of the Caribbean in the Leeward Antilles islands is transected by an en echelon series of obliquely-sheared rift basins that show right-lateral offsets ranging from 20 to 40 km. The basins are 75-100 km in length and 20-30 km in width and are composed of sub-parallel, oblique slip normal faults that define deep, bathymetric channels that bound the larger islands of the Leeward Antilles including Aruba, Curacao and Bonaire. A single basin of similar orientation and structure, the Urumaco basin, is present to the southwest in the Gulf of Venezuela. We mapped structures and sedimentation in the La Vela rift basin using a 3D seismic data volume recorded down to 6 seconds TWT. The basin can be mapped from the Falcon coast where it is correlative with the right-lateral Adicora fault mapped onshore, and its submarine extension. To the southeast of the 3D survey area, previous workers have mapped a 70-km-wide zone of northeast-striking, oblique, right-lateral faults, some with apparent right-lateral offsets of the coastline. On seismic data, the faults vary in dip from 45 to 60 degrees and exhibit maximum vertical offsets of 600 m. The La Vela and other obliquely-opening rifts accommodate right-lateral shear with linkages to intervening, east-west-striking right-lateral faults like the Adicora. The zone of oblique rifts is restricted to the trend of the Great Arc of the Caribbean and may reflect the susceptiblity of this granitic basement to active shearing. The age of onset for the basins known from previous studies on the Leeward Antilles is early Miocene. As most of these faults occur offshore their potential to generate damaging earthquakes in the densely populated Leeward Antilles is not known.

  10. Geomorphic Evidence of a Complex late-Cenozoic Uplift and Lateral Displacement History Along the 2013 M7.7 Baluchistan, Pakistan Strike-slip Rupture

    Science.gov (United States)

    Harbor, D. J.; Barnhart, W. D.

    2017-12-01

    The 2013 M7.7 Baluchistan earthquake in southern Pakistan ruptured 200 km of the north-dipping Hoshab reverse fault with dominantly lateral motion, clearly at odds with the regional topography created by previous reverse fault offsets. The kinematics of this earthquake led to the hypotheses that the Hoshab fault may alternatively slip in a reverse and lateral sense (bi-modal slip), and that the southeast Makran rotates as a uniform block around the fault (ball-and-socket rotation). Here, we use river profiles, regional relief, fault locations, and detailed geomorphic maps derived from optical imagery and DEMs to evaluate the recent uplift history of this region. We find that late Cenozoic fault zone geomorphology supports a spatially complex transition from lateral-dominated offsets in the NE to reverse-dominated offsets in the SW. Additionally, fault zone geomorphology suggests that the location of the Hoshab fault itself may change through time, leading to active incision of footwall alluvial fans and pediments. Stream profiles likewise record incision patterns that vary along the Hoshab fault. Incision and deposition in the SW are illustrative of relative footwall subsidence, consistent with recent uplift on the Hoshab fault; whereas incision and deposition in the NE are illustrative of relative footwall uplift consistent with ongoing regional uplift due to ball-and-socket rotations and dominantly lateral offsets along the northern Hoshab fault. The largest streams also record multiple, discrete, base-level drops, including the presence of convex-up river profiles in the hanging wall of the Hoshab fault. These profiles along hanging wall streams highlight a complex spatial and temporal history of reverse offset, lateral channel offset, and base-level resetting in regional streams that are altogether inconsistent with the kinematics of the 2013 earthquake alone, but that are consistent with the bi-modal slip model. Additionally, the evidence of footwall uplift in the NE is consistent with regional uplift due to ball-and-socket rotations superimposed on the Hoshab fault. These results indicate that the styles of fault slip in the Makran change in time and space in response to ongoing convergence and block rotations despite negligible uplift during the 2013 earthquake.

  11. Breaching of strike-slip faults and flooding of pull-apart basins to form the southern Gulf of California seaway from 8 to 6 Ma

    Science.gov (United States)

    Umhoefer, P. J.; Skinner, L. A.; Oskin, M. E.; Dorsey, R. J.; Bennett, S. E. K.; Darin, M. H.

    2017-12-01

    Studies from multiple disciplines delineate the development of the oblique-divergent Pacific - North America plate boundary in the southern Gulf of California. Integration of onshore data from the Loreto - Santa Rosalia margin with offshore data from the Pescadero, Farallon, and Guaymas basins provides a detailed geologic history. Our GIS-based paleotectonic maps of the plate boundary from 9 to 6 Ma show that evolution of pull-apart basins led to the episodic northwestward encroachment of the Gulf of California seaway. Because adjacent pull-apart basins commonly have highlands between them, juxtaposition of adjacent basin lows during translation and pull apart lengthening played a critical role in seaway flooding. Microfossils and volcanic units date the earliest marine deposits at 9(?) - 8 Ma at the mouth of the Gulf. By ca. 8 Ma, the seaway had flooded north to the Pescadero basin, while the Loreto fault and the related fault-termination basin was proposed to have formed along strike at the plate margin. East of Loreto basin, a short topographic barrier between the Pescadero and Farallon pull-apart basins suggests that the Farallon basin was either a terrestrial basin, or if breaching occurred, it may contain 8 Ma salt or marine deposits. This early southern seaway formed along a series of pull-apart basins within a narrow belt of transtension structurally similar to the modern Walker Lane in NV and CA. At ca. 7 Ma, a series of marine incursions breached a 75-100 km long transtensional fault barrier between the Farallon and Guaymas basins offshore Bahía Concepción. Repeated breaching events and the isolation of the Guaymas basin in a subtropical setting formed a 2 km-thick salt deposit imaged in offshore seismic data, and thin evaporite deposits in the onshore Santa Rosalia basin. Lengthening of the Guaymas, Yaqui, and Tiburon basins caused breaches of the intervening Guaymas and Tiburón transforms by 6.5-6.3 Ma, forming a permanent 1500 km-long marine seaway up to the Salton Trough. By 6 Ma, the Guaymas basin had uniquely evolved to oceanic seafloor spreading, while the marine seaway to the south remained a series of pull-apart and transtensional basins with seafloor spreading delayed until 3 - 2 Ma. There is evidence of rift flank uplift near the Loreto fault/basin in this 6 - 3 Ma transitional period.

  12. Structural evolution of Cenozoic basins in northeastern Tunisia, in response to sinistral strike-slip movement on the El Alia-Teboursouk Fault

    Science.gov (United States)

    Bejaoui, Hamida; Aïfa, Tahar; Melki, Fetheddine; Zargouni, Fouad

    2017-10-01

    This paper resolves the structural complexity of Cenozoic sedimentary basins in northeastern Tunisia. These basins trend NE-SW to ∼ E-W, and are bordered by old fracture networks. Detailed descriptions of the structural features in outcrop and in subsurface data suggest that the El Alia-Teboursouk Fault zone in the Bizerte area evolved through a series of tectonic events. Cross sections, lithostratigraphic correlations, and interpretation of seismic profiles through the basins show evidence for: (i) a Triassic until Jurassic-Early Cretaceous rifting phase that induced lateral variations of facies and strata thicknesses; (ii) a set of faults oriented NE-SW, NW-SE, N-S, and E-W that guided sediment accumulation in pull-apart basins, which were subject to compressive and transpressive deformation during Eocene (Lutetian-Priabonian), Miocene (Tortonian), and Pliocene-Quaternary; and (iii) NNW-SSE to NS contractional events that occurred during the Late Pliocene. Part of the latest phase has been the formation of different synsedimentary folded structures with significant subsidence inversion. Such events have been responsible for the reactivation of inherited faults, and the intrusion of Triassic evaporites, ensuring the role of a slip layer. The combined effects of the different paleoconstraints and halokinetic movements are at the origin of the evolution of these pull-apart basins. The subsurface data suggest that an important fault displacement occurred during the Mesozoic-Cenozoic. The patterns of sediment accumulation in the different basins reflect a high activity of deep ancient faults.

  13. Vertical-axis rotations and deformation along the active strike-slip El Tigre Fault (Precordillera of San Juan, Argentina) assessed through palaeomagnetism and anisotropy of magnetic susceptibility

    Science.gov (United States)

    Fazzito, Sabrina Y.; Rapalini, Augusto E.; Cortés, José M.; Terrizzano, Carla M.

    2017-03-01

    Palaeomagnetic data from poorly consolidated to non-consolidated late Cenozoic sediments along the central segment of the active El Tigre Fault (Central-Western Precordillera of the San Juan Province, Argentina) demonstrate broad cumulative deformation up to 450 m from the fault trace and reveal clockwise and anticlockwise vertical-axis rotations of variable magnitude. This deformation has affected in different amounts Miocene to late Pleistocene samples and indicates a complex kinematic pattern. Several inherited linear structures in the shear zone that are oblique to the El Tigre Fault may have acted as block boundary faults. Displacement along these faults may have resulted in a complex pattern of rotations. The maximum magnitude of rotation is a function of the age of the sediments sampled, with largest values corresponding to middle Miocene-lower Pliocene deposits and minimum values obtained from late Pleistocene deposits. The kinematic study is complemented by low-field anisotropy of magnetic susceptibility data to show that the local strain regime suggests a N-S stretching direction, subparallel to the strike of the main fault.

  14. Pleistocene Brawley and Ocotillo Formations: Evidence for initial strike-slip deformation along the San Felipe and San Jacinto fault zonez, Southern California

    Science.gov (United States)

    Kirby, S.M.; Janecke, S.U.; Dorsey, R.J.; Housen, B.A.; Langenheim, V.E.; McDougall, K.A.; Steeley, A.N.

    2007-01-01

    We examine the Pleistocene tectonic reorganization of the Pacific-North American plate boundary in the Salton Trough of southern California with an integrated approach that includes basin analysis, magnetostratigraphy, and geologic mapping of upper Pliocene to Pleistocene sedimentary rocks in the San Felipe Hills. These deposits preserve the earliest sedimentary record of movement on the San Felipe and San Jacinto fault zones that replaced and deactivated the late Cenozoic West Salton detachment fault. Sandstone and mudstone of the Brawley Formation accumulated between ???1.1 and ???0.6-0.5 Ma in a delta on the margin of an arid Pleistocene lake, which received sediment from alluvial fans of the Ocotillo Formation to the west-southwest. Our analysis indicates that the Ocotillo and Brawley formations prograded abruptly to the east-northeast across a former mud-dominated perennial lake (Borrego Formation) at ???1.1 Ma in response to initiation of the dextral-oblique San Felipe fault zone. The ???25-km-long San Felipe anticline initiated at about the same time and produced an intrabasinal basement-cored high within the San Felipe-Borrego basin that is recorded by progressive unconformities on its north and south limbs. A disconformity at the base of the Brawley Formation in the eastern San Felipe Hills probably records initiation and early blind slip at the southeast tip of the Clark strand of the San Jacinto fault zone. Our data are consistent with abrupt and nearly synchronous inception of the San Jacinto and San Felipe fault zones southwest of the southern San Andreas fault in the early Pleistocene during a pronounced southwestward broadening of the San Andreas fault zone. The current contractional geometry of the San Jacinto fault zone developed after ???0.5-0.6 Ma during a second, less significant change in structural style. ?? 2007 by The University of Chicago. All rights reserved.

  15. 40Ar/39Ar thermo-chronology and lithospheric mechanisms. Methodological and applied approach: the Kunlun range (Asia) and the Afar triple junction area (East Africa)

    International Nuclear Information System (INIS)

    Mock, C.

    1998-01-01

    A 40 Ar/ 39 Ar thermo-chronological study has been carried out for two contrasted geodynamic settings: - the Eastern Kunlun range (Northern Tibet), in order to characterize the lithospheric deformation mechanisms related to the India-Asia collision; - the Afar triple junction area (East Africa), in order to constrain the timing of mantle plume-related basement uplift in Ethiopia and Yemen, which will indicate whether rifting was active or passive. In the Kunlun, the cooling event (9-15 deg.C/Ma) outlined at 30 Ma for the granitoids (Bt = 128-138 Ma; Kf = 102-147 Ma) reflects a denudation event (0.2-0.3 km/Ma), related to ramp stacking and normal faulting with associated uplift. This unroofing period is coeval with the great Asian strike-slip faults. This suggests that 30 Ma ago, the India-Asia collision was accommodated by lateral extrusion along great strike-slip faults, which might have led to local crustal thickening because of the formation of anticlines from major thrusts 'branching' from the Kunlun fault. In the Afar area the Panafrican basement (granitoids = 462-678 Ma;metamorphic rocks 505-750 Ma) has undergone a reheating event during the Cenozoic; its temperature is estimated around 138-177 deg.C over the last 50 Ma for a depth of 2 km, implying a thermal gradient of 69-88 deg./km. This reheating event results from both heat conduction, related to the mantle plume. and heat advection. because of magma transfer. However, it was not possible to define the timing of the mantle plume-related basement uplift. This study outlines the important thermal effect of continental flood basalts on the crust and suggests that the 40 Ar/ 39 Ar thermo-chronology does not allow to characterize the denudation of the lithosphere for an extension-type geodynamic setting. Finally, some of the results suggest that diffusion in the laboratory and in nature may be different. 40 Ar/ 39 Ar thermo-chronological analysis thus might be tricky, especially in investigating geologic

  16. 2016-2017 Update of Hydraulic Fracturing Induced Earthquakes near Fox Creek, Alberta

    Science.gov (United States)

    Wang, R.; Gu, Y. J.; Zhang, M.

    2017-12-01

    With a reported Richter magnitude (ML) of 4.8, the January 12, 2016 earthquake near Fox Creek is the largest event in Alberta during the past decade. This event led to the suspension of a nearby hydraulic fracturing well, in compliance with the provincial "traffic-light" protocol. In previous study, we examine the hypocenter location and focal mechanism of this earthquake, and the results support an anthropogenic origin. Since then (until August 2017), no event reached ML=4, while several ML>3 events occurred in the Fox Creek area. Their focal mechanisms are consistent with the ones from previous events that were induced by hydraulic fracturing, suggesting a strike-slip mechanism with either N-S or E-W trending fault. In 2017, the near-source station (distance Fox Creek region.

  17. Second-hit mosaic mutation in mTORC1 repressor DEPDC5 causes focal cortical dysplasia-associated epilepsy.

    Science.gov (United States)

    Ribierre, Théo; Deleuze, Charlotte; Bacq, Alexandre; Baldassari, Sara; Marsan, Elise; Chipaux, Mathilde; Muraca, Giuseppe; Roussel, Delphine; Navarro, Vincent; Leguern, Eric; Miles, Richard; Baulac, Stéphanie

    2018-04-30

    DEP domain-containing 5 protein (DEPDC5) is a repressor of the recently recognized amino acid-sensing branch of the mTORC1 pathway. So far, its function in the brain remains largely unknown. Germline loss-of-function mutations in DEPDC5 have emerged as a major cause of familial refractory focal epilepsies, with case reports of sudden unexpected death in epilepsy (SUDEP). Remarkably, a fraction of patients also develop focal cortical dysplasia (FCD), a neurodevelopmental cortical malformation. We therefore hypothesized that a somatic second-hit mutation arising during brain development may support the focal nature of the dysplasia. Here, using postoperative human tissue, we provide the proof of concept that a biallelic 2-hit - brain somatic and germline - mutational mechanism in DEPDC5 causes focal epilepsy with FCD. We discovered a mutation gradient with a higher rate of mosaicism in the seizure-onset zone than in the surrounding epileptogenic zone. Furthermore, we demonstrate the causality of a Depdc5 brain mosaic inactivation using CRISPR-Cas9 editing and in utero electroporation in a mouse model recapitulating focal epilepsy with FCD and SUDEP-like events. We further unveil a key role of Depdc5 in shaping dendrite and spine morphology of excitatory neurons. This study reveals promising therapeutic avenues for treating drug-resistant focal epilepsies with mTORC1-targeting molecules.

  18. Mechanics

    CERN Document Server

    Chester, W

    1979-01-01

    When I began to write this book, I originally had in mind the needs of university students in their first year. May aim was to keep the mathematics simple. No advanced techniques are used and there are no complicated applications. The emphasis is on an understanding of the basic ideas and problems which require expertise but do not contribute to this understanding are not discussed. How­ ever, the presentation is more sophisticated than might be considered appropri­ ate for someone with no previous knowledge of the subject so that, although it is developed from the beginning, some previous acquaintance with the elements of the subject would be an advantage. In addition, some familiarity with element­ ary calculus is assumed but not with the elementary theory of differential equations, although knowledge of the latter would again be an advantage. It is my opinion that mechanics is best introduced through the motion of a particle, with rigid body problems left until the subject is more fully developed. Howev...

  19. Radiologic manifestations of focal cerebral hyperemia in acute stroke

    DEFF Research Database (Denmark)

    Olsen, Tom Skyhøj; Skriver, E B; Herning, M

    1991-01-01

    In 16 acute stroke patients with focal cerebral hyperemia angiography and regional cerebral blood flow (rCBF) were studied 1 to 4 days post stroke. CT was performed twice with and without contrast enhancement 3 +/- 1 days and 16 +/- 4 days post stroke. Angiographic evidence of focal cerebral hype...

  20. Focal decompositions for linear differential equations of the second order

    Directory of Open Access Journals (Sweden)

    L. Birbrair

    2003-01-01

    two-points problems to itself such that the image of the focal decomposition associated to the first equation is a focal decomposition associated to the second one. In this paper, we present a complete classification for linear second-order equations with respect to this equivalence relation.

  1. Focal necrotizing pneumonia is a distinct entity from lung abscess.

    Science.gov (United States)

    Seo, Hyewon; Cha, Seung-Ick; Shin, Kyung-Min; Lim, Jaekwang; Yoo, Seung-Soo; Lee, Jaehee; Lee, Shin-Yup; Kim, Chang-Ho; Park, Jae-Yong

    2013-10-01

    'Focal necrotizing pneumonia' was defined as a localized type of necrotizing pneumonia characterized by a single or few cavities of low density without rim enhancement on computed tomography (CT) scan. The purpose of this study was to investigate the clinical features and course of patients with focal necrotizing pneumonia, thereby elucidating its clinical relevance. The present study was conducted retrospectively in patients who had been interpreted as having lung abscess or necrotizing pneumonia on CT scan. Clinical and radiological characteristics were compared between the focal necrotizing pneumonia and lung abscess groups. Overall, 68 patients with focal necrotizing pneumonia (n = 35) or lung abscess (n = 33) were included in the present study. The frequency of risk factors for aspiration was significantly lower in the focal necrotizing group, compared with the lung abscess group (14.3% vs 45.5%, P = 0.005). Compared with lung abscess, focal necrotizing pneumonia was observed more commonly in non-gravity-dependent segments (66% vs 36%, P lung abscess group (31% vs 12%, P = 0.08). However, in terms of treatment outcomes, a similar high rate of success was observed in both groups: 97%, respectively. Compared to lung abscess, focal necrotizing pneumonia occurs more commonly in non-gravity-dependent segments with lower incidence of risk factors for aspiration. Similar to lung abscess, the rate of success for treatment of focal necrotizing pneumonia was high. © 2013 The Authors. Respirology © 2013 Asian Pacific Society of Respirology.

  2. Proximal Focal Femoral Deficiency in Ibadan a Developing ...

    African Journals Online (AJOL)

    The cultural aversion to amputation in our environment makes it difficult to employ that option of treatment. Proximal focal femoral deficiency in Ibadan a developing country's perspective and a review of the literature. Keywords: Proximal focal femoral deficiency , congenital malformations , limb malformations , lower limb ...

  3. Concordance of MRI and EEG Focal Slowing in Nonsyndromic Epilepsy

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2013-04-01

    Full Text Available Investigators at the Kangwon National University, Korea, and The Epilepsy Center, Lurie Children’s Hospital of Chicago, USA studied the correlation and significance of EEG focal slowing and focal MRI abnormalities in 253 children with nonsyndromic epilepsy.

  4. Antigen-driven focal inflammatory death of malaria liver stages

    Directory of Open Access Journals (Sweden)

    Ganchimeg eBayarsaikhan

    2015-02-01

    Full Text Available Multiple immunizations using live irradiated sporozoites, the infectious plasmodial stage delivered into the host skin during a mosquito bite, can elicit sterile immunity to malaria. CD8+ T cells seem to play an essential role in this protective immunity, since their depletion consistently abolishes sterilizing protection in several experimental models. So far, only a few parasite antigens are known to induce CD8+ T cell-dependent protection, but none of them can reach the levels of protection afforded by live attenuated parasites. Systematic attempts to identify novel antigens associated with this efficient cellular protection were so far unsuccessful. In addition, the precise mechanisms involved in the recognition and elimination of parasitized hepatocytes in vivo by CD8+ T cells still remain obscure. Recently, it has been shown that specific effector CD8+ T cells, after recognition of parasitized hepatocytes, recruit specific and non-specific activated CD8+ T cells to the site of infection, resulting in the formation of cellular clusters around and in the further elimination of intracellular parasites. The significance of this finding is discussed in the perspective of a general mechanism of antigen-dependent focalized inflammation and its consequences for the elimination of malaria liver stages.

  5. Focal Dystonia and the Sensory-Motor Integrative Loop for Enacting (SMILE)

    OpenAIRE

    David ePerruchoud; Micah M Murray; Micah M Murray; Jeremie eLefebvre; Silvio eIonta

    2014-01-01

    Performing accurate movements requires preparation, execution, and monitoring mechanisms. The first two are coded by the motor system, and the latter by the sensory system. To provide an adaptive neural basis to overt behaviors, motor and sensory information has to be properly integrated in a reciprocal feedback loop. Abnormalities in this sensory-motor loop are involved in movement disorders such as focal dystonia, a hyperkinetic alteration affecting only a specific body part and characteriz...

  6. Focal dystonia and the Sensory-Motor Integrative Loop for Enacting (SMILE)

    OpenAIRE

    Perruchoud David; Murray Micah; Lefebvre Jeremie; Ionta Silvio

    2014-01-01

    Performing accurate movements requires preparation, execution, and monitoring mechanisms. The first two are coded by the motor system, the latter by the sensory system. To provide an adaptive neural basis to overt behaviors, motor and sensory information has to be properly integrated in a reciprocal feedback loop. Abnormalities in this sensory-motor loop are involved in movement disorders such as focal dystonia, a hyperkinetic alteration affecting only a specific body part and characterized b...

  7. An empirical assessment of the focal species hypothesis.

    Science.gov (United States)

    Lindenmayer, D B; Lane, P W; Westgate, M J; Crane, M; Michael, D; Okada, S; Barton, P S

    2014-12-01

    Biodiversity surrogates and indicators are commonly used in conservation management. The focal species approach (FSA) is one method for identifying biodiversity surrogates, and it is underpinned by the hypothesis that management aimed at a particular focal species will confer protection on co-occurring species. This concept has been the subject of much debate, in part because the validity of the FSA has not been subject to detailed empirical assessment of the extent to which a given focal species actually co-occurs with other species in an assemblage. To address this knowledge gap, we used large-scale, long-term data sets of temperate woodland birds to select focal species associated with threatening processes such as habitat isolation and loss of key vegetation attributes. We quantified co-occurrence patterns among focal species, species in the wider bird assemblage, and species of conservation concern. Some, but not all, focal species were associated with high levels of species richness. One of our selected focal species was negatively associated with the occurrence of other species (i.e., it was an antisurrogate)-a previously undescribed property of nominated focal species. Furthermore, combinations of focal species were not associated with substantially elevated levels of bird species richness, relative to levels associated with individual species. Our results suggest that although there is some merit to the underpinning concept of the FSA, there is also a need to ensure that actions are sufficiently flexible because management tightly focused on a given focal species may not benefit some other species, including species of conservation concern, such of which might not occur in species-rich assemblages. © 2014 Society for Conservation Biology.

  8. [Sotos syndrome associated with focal dystonia].

    Science.gov (United States)

    Bravo, M; Chacón, J; Bautista, E; Pérez-Camacho, I; Trujillo, A; Grande, M A

    Sotos syndrome is a form of infantile gigantism characterized by excessive body size from the time of birth, particular facies, acromegalic changes and signs of non-progressive cerebral involvement. The etiology is unknown. Diagnosis is based on somatometric data and the particular phenotype traits. Biochemical and endocrine studies are normal. Torticollis is a focal dystonia and therefore more common in adults. A 20 year old woman with macrosomic features since birth presented with: weight 104 kg, height 182 cm; prognathism, hypertelorism, a broad over hanging forehead with a high hair line; large ears, hands and feet; torticollis towards the right with elevation and anteroversion of the right shoulder which caused symptomatic scoliosis. She was bradypsychic and rather slow in speech. The complementary tests done (cerebral and cervical CT and MR, bone gammography, evoked potentials, EMG-ENG, sural nerve biopsy, biopsy of skin and muscle, EEG and hormone and biochemistry studies) were normal. The torticollis was treated with botulinus toxin and improved considerably, as did the scoliosis. To date, dystonia has not been described in association with Sotos syndrome. This may be a causal association, or even perhaps hereditary, since the patient's mother had dystonia (in the form of blepharospasm).

  9. Depression in focal, segmental and generalized dystonia.

    Science.gov (United States)

    Lewis, L; Butler, A; Jahanshahi, M

    2008-11-01

    Dystonia causes body disfigurement in the majority of those affected. Our aim was to test the hypothesis that low self-esteem resulting from the sense of disfigurement is an important component of self-reported depression in focal, segmental and generalized dystonia. Questionnaires to assess self-reported depression, self-esteem, body concept, disfigurement, disability and quality of life were completed by 329 community based dystonia patients. Moderate to severe depression was reported by 30 %. Self-reported depression had a strong somatic component, but patients also showed a specific concern with self-image. Extent of dystonia, body parts affected and marital status influenced self-reported depression in dystonia. Self esteem, body concept, disfigurement and quality of life emerged as factors which accounted for the variance of self-reported depression in dystonia. These results suggest that in dystonia, disfigurement, negative body concept, low self-esteem, and the impact of the disease on quality of life make important contributions to depression. However, longitudinal followup is required to firmly establish the direction of causality between depression and these psychosocial variables in dystonia.

  10. Visual agnosia and focal brain injury.

    Science.gov (United States)

    Martinaud, O

    Visual agnosia encompasses all disorders of visual recognition within a selective visual modality not due to an impairment of elementary visual processing or other cognitive deficit. Based on a sequential dichotomy between the perceptual and memory systems, two different categories of visual object agnosia are usually considered: 'apperceptive agnosia' and 'associative agnosia'. Impaired visual recognition within a single category of stimuli is also reported in: (i) visual object agnosia of the ventral pathway, such as prosopagnosia (for faces), pure alexia (for words), or topographagnosia (for landmarks); (ii) visual spatial agnosia of the dorsal pathway, such as cerebral akinetopsia (for movement), or orientation agnosia (for the placement of objects in space). Focal brain injuries provide a unique opportunity to better understand regional brain function, particularly with the use of effective statistical approaches such as voxel-based lesion-symptom mapping (VLSM). The aim of the present work was twofold: (i) to review the various agnosia categories according to the traditional visual dual-pathway model; and (ii) to better assess the anatomical network underlying visual recognition through lesion-mapping studies correlating neuroanatomical and clinical outcomes. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  11. Nonhuman primate models of focal cerebral ischemia

    Directory of Open Access Journals (Sweden)

    Jingjing Fan

    2017-01-01

    Full Text Available Rodents have been widely used in the production of cerebral ischemia models. However, successful therapies have been proven on experimental rodent stroke model, and they have often failed to be effective when tested clinically. Therefore, nonhuman primates were recommended as the ideal alternatives, owing to their similarities with the human cerebrovascular system, brain metabolism, grey to white matter ratio and even their rich behavioral repertoire. The present review is a thorough summary of ten methods that establish nonhuman primate models of focal cerebral ischemia; electrocoagulation, endothelin-1-induced occlusion, microvascular clip occlusion, autologous blood clot embolization, balloon inflation, microcatheter embolization, coil embolization, surgical suture embolization, suture, and photochemical induction methods. This review addresses the advantages and disadvantages of each method, as well as precautions for each model, compared nonhuman primates with rodents, different species of nonhuman primates and different modeling methods. Finally it discusses various factors that need to be considered when modelling and the method of evaluation after modelling. These are critical for understanding their respective strengths and weaknesses and underlie the selection of the optimum model.

  12. Evaluation of Hemodynamics in Focal Steatosis and Focal Spared Lesion of the Liver Using Contrast-Enhanced Ultrasonography with Sonazoid

    International Nuclear Information System (INIS)

    Shiozawa, K.; Watanabe, M.; Ikehara, T.; Kogame, M.; Shinohara, M.; Shinohara, M.; Ishii, K.; Igarashi, Y.; Sumino, Y.; Shiozawa, K.; Makino, H.

    2014-01-01

    We aim to investigate the hemodynamics in focal steatosis and focal spared lesion of the liver using contrast-enhanced ultrasonography (CEUS) with Sonazoid. The subjects were 47 patients with focal steatosis and focal spared lesion. We evaluated enhancement patterns (hyper enhancement, iso enhancement, and hypo enhancement) in the vascular phase and the presence or absence of a hypoechoic area in the post vascular phase for these lesions using CEUS. Of the 24 patients with focal steatosis, the enhancement pattern was iso enhancement in 19 and hypo enhancement in 5. Hypoechoic areas were noted in the post vascular phase in 3 patients. Of the 23 patients with focal spared lesions, the enhancement pattern was iso enhancement in 18 and hyper enhancement in 5. No hypoechoic areas were noted in the post vascular phase in any patient. The hemodynamics in focal steatosis and focal spared lesions in non diffuse fatty liver can be observed using low-invasive procedures in real-time by CEUS. It was suggested that differences in the dynamics of enhancement in the vascular phase of CEUS were influenced by the fat deposits in the target lesion, the surrounding liver parenchyma, and the third inflow.

  13. Landsat 9 OLI 2 focal plane subsystem: design, performance, and status

    Science.gov (United States)

    Malone, Kevin J.; Schrein, Ronald J.; Bradley, M. Scott; Irwin, Ronda; Berdanier, Barry; Donley, Eric

    2017-09-01

    The Landsat 9 mission will continue the legacy of Earth remote sensing that started in 1972. The Operational Land Imager 2 (OLI 2) is one of two instruments on the Landsat 9 satellite. The OLI 2 instrument is essentially a copy of the OLI instrument flying on Landsat 8. A key element of the OLI 2 instrument is the focal plane subsystem, or FPS, which consists of the focal plane array (FPA), the focal plane electronics (FPE) box, and low-thermal conductivity cables. This paper presents design details of the OLI 2 FPS. The FPA contains 14 critically-aligned focal plane modules (FPM). Each module contains 6 visible/near-IR (VNIR) detector arrays and three short-wave infrared (SWIR) arrays. A complex multi-spectral optical filter is contained in each module. Redundant pixels for each array provide exceptional operability. Spare detector modules from OLI were recharacterized after six years of storage. Radiometric test results are presented and compared with data recorded in 2010. Thermal, optical, mechanical and structural features of the FPA will be described. Special attention is paid to the thermal design of the FPA since thermal stability is crucial to ensuring low-noise and low-drift operation of the detectors which operate at -63°C. The OLI 2 FPE provides power, timing, and control to the focal plane modules. It also digitizes the video data and formats it for the solid-state recorder. Design improvements to the FPA-FPE cables will be discussed and characterization data will be presented. The paper will conclude with the status of the flight hardware assembly and testing.

  14. Hemopexin induces neuroprotection in the rat subjected to focal cerebral ischemia.

    Science.gov (United States)

    Dong, Beibei; Cai, Min; Fang, Zongping; Wei, Haidong; Zhu, Fangyun; Li, Guochao; Dong, Hailong; Xiong, Lize

    2013-06-10

    The plasma protein hemopexin (HPX) exhibits the highest binding affinity to free heme. In vitro experiments and gene-knock out technique have suggested that HPX may have a neuroprotective effect. However, the expression of HPX in the brain was not well elucidated and its expression after cerebral ischemia-reperfusion injury was also poorly studied. Furthermore, no in vivo data were available on the effect of HPX given centrally on the prognosis of focal cerebral ischemia. In the present study, we systematically investigated expression of HPX in normal rat brain by immunofluorescent staining. The results showed that HPX was mainly expressed in vascular system and neurons, as well as in a small portion of astrocytes adjacent to the vessels in normal rat brain. Further, we determined the role of HPX in the process of focal cerebral ischemic injury and explored the effects of HPX treatment in a rat model of transient focal cerebral ischemia. After 2 h' middle cerebral artery occlusion (MCAO) followed by 24 h' reperfusion, the expression of HPX was increased in the neurons and astrocytes in the penumbra area, as demonstrated by immunohistochemistry and Western blot techniques. Intracerebroventricular injection of HPX at the onset of reperfusion dose-dependently reduced the infarct volumes and improved measurements of neurological function of the rat subjected to transient focal cerebral ischemia. The neuroprotective effects of HPX sustained for up to 7 days after experiments. Our study provides a new insight into the potential neuroprotective role of HPX as a contributing factor of endogenous protective mechanisms against focal cerebral ischemia injury, and HPX might be developed as a potential agent for treatment of ischemic stroke.

  15. Focal Atrichia: A Diagnostic Clue in Female Pattern Hair Loss.

    Science.gov (United States)

    Olsen, Elise A; Whiting, David A

    2017-10-07

    Focal atrichia is a common clinical finding in female pattern hair loss whose specificity and histologic findings need further clarification. To determine the frequency of focal atrichia in various types of hair loss and its histologic characteristics in female pattern hair loss. Part 1: Review of 250 consecutive female patients seen with hair loss for the presence of focal atrichia and Part 2: paired biopsies of haired areas vs focal atrichia in 18 subjects with female pattern hair loss RESULTS: Focal atrichia was seen in 46/104 (44%) of women with female pattern hair loss, including 67% of late onset vs 15% of early onset, compared to 3/146 (2%) of those with other hair disorders Biopsy findings of focal atrichia in female pattern hair loss showed primarily a more progressive miniaturization process than that of haired areas of the scalp. Some women with female pattern hair loss may have had concomitant chronic telogen effluvium CONCLUSIONS: When present, focal atrichia is a clinical clue to the diagnosis of female pattern hair loss, particularly late onset subtype. Copyright © 2017. Published by Elsevier Inc.

  16. The semiology of febrile seizures: Focal features are frequent.

    Science.gov (United States)

    Takasu, Michihiko; Kubota, Tetsuo; Tsuji, Takeshi; Kurahashi, Hirokazu; Numoto, Shingo; Watanabe, Kazuyoshi; Okumura, Akihisa

    2017-08-01

    To clarify the semiology of febrile seizures (FS) and to determine the frequency of FS with symptoms suggestive of focal onset. FS symptoms in children were reported within 24h of seizure onset by the parents using a structured questionnaire consisting principally of closed-ended questions. We focused on events at seizure commencement, including changes in behavior and facial expression, and ocular and oral symptoms. We also investigated the autonomic and motor symptoms developing during seizures. The presence or absence of focal and limbic features was determined for each patient. The associations of certain focal and limbic features with patient characteristics were assessed. Information was obtained on FS in 106 children. Various events were recorded at seizure commencement. Behavioral changes were observed in 35 children, changes in facial expression in 53, ocular symptoms in 78, and oral symptoms in 90. In terms of events during seizures, autonomic symptoms were recognized in 78, and convulsive motor symptoms were recognized in 68 children. Focal features were evident in 81 children; 38 children had two or more such features. Limbic features were observed in 44 children, 9 of whom had two or more such features. There was no significant relationship between any patient characteristic and the numbers of focal or limbic features. The semiology of FS varied widely among children, and symptoms suggestive of focal onset were frequent. FS of focal onset may be more common than is generally thought. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. The dispersion-focalization theory of sound systems

    Science.gov (United States)

    Schwartz, Jean-Luc; Abry, Christian; Boë, Louis-Jean; Vallée, Nathalie; Ménard, Lucie

    2005-04-01

    The Dispersion-Focalization Theory states that sound systems in human languages are shaped by two major perceptual constraints: dispersion driving auditory contrast towards maximal or sufficient values [B. Lindblom, J. Phonetics 18, 135-152 (1990)] and focalization driving auditory spectra towards patterns with close neighboring formants. Dispersion is computed from the sum of the inverse squared inter-spectra distances in the (F1, F2, F3, F4) space, using a non-linear process based on the 3.5 Bark critical distance to estimate F2'. Focalization is based on the idea that close neighboring formants produce vowel spectra with marked peaks, easier to process and memorize in the auditory system. Evidence for increased stability of focal vowels in short-term memory was provided in a discrimination experiment on adult French subjects [J. L. Schwartz and P. Escudier, Speech Comm. 8, 235-259 (1989)]. A reanalysis of infant discrimination data shows that focalization could well be the responsible for recurrent discrimination asymmetries [J. L. Schwartz et al., Speech Comm. (in press)]. Recent data about children vowel production indicate that focalization seems to be part of the perceptual templates driving speech development. The Dispersion-Focalization Theory produces valid predictions for both vowel and consonant systems, in relation with available databases of human languages inventories.

  18. Stretch activates human myometrium via ERK, caldesmon and focal adhesion signaling.

    Directory of Open Access Journals (Sweden)

    Yunping Li

    2009-10-01

    Full Text Available An incomplete understanding of the molecular mechanisms responsible for myometrial activation from the quiescent pregnant state to the active contractile state during labor has hindered the development of effective therapies for preterm labor. Myometrial stretch has been implicated clinically in the initiation of labor and the etiology of preterm labor, but the molecular mechanisms involved in the human have not been determined. We investigated the mechanisms by which gestation-dependent stretch contributes to myometrial activation, by using human uterine samples from gynecologic hysterectomies and Cesarean sections. Here we demonstrate that the Ca requirement for activation of the contractile filaments in human myometrium increases with caldesmon protein content during gestation and that an increase in caldesmon phosphorylation can reverse this inhibitory effect during labor. By using phosphotyrosine screening and mass spectrometry of stretched human myometrial samples, we identify 3 stretch-activated focal adhesion proteins, FAK, p130Cas, and alpha actinin. FAK-Y397, which signals integrin engagement, is constitutively phosphorylated in term human myometrium whereas FAK-Y925, which signals downstream ERK activation, is phosphorylated during stretch. We have recently identified smooth muscle Archvillin (SmAV as an ERK regulator. A newly produced SmAV-specific antibody demonstrates gestation-specific increases in SmAV protein levels and stretch-specific increases in SmAV association with focal adhesion proteins. Thus, whereas increases in caldesmon levels suppress human myometrium contractility during pregnancy, stretch-dependent focal adhesion signaling, facilitated by the ERK activator SmAV, can contribute to myometrial activation. These results suggest that focal adhesion proteins may present new targets for drug discovery programs aimed at regulation of uterine contractility.

  19. Widespread EEG changes precede focal seizures.

    Directory of Open Access Journals (Sweden)

    Piero Perucca

    Full Text Available The process by which the brain transitions into an epileptic seizure is unknown. In this study, we investigated whether the transition to seizure is associated with changes in brain dynamics detectable in the wideband EEG, and whether differences exist across underlying pathologies. Depth electrode ictal EEG recordings from 40 consecutive patients with pharmacoresistant lesional focal epilepsy were low-pass filtered at 500 Hz and sampled at 2,000 Hz. Predefined EEG sections were selected immediately before (immediate preictal, and 30 seconds before the earliest EEG sign suggestive of seizure activity (baseline. Spectral analysis, visual inspection and discrete wavelet transform were used to detect standard (delta, theta, alpha, beta and gamma and high-frequency bands (ripples and fast ripples. At the group level, each EEG frequency band activity increased significantly from baseline to the immediate preictal section, mostly in a progressive manner and independently of any modification in the state of vigilance. Preictal increases in each frequency band activity were widespread, being observed in the seizure-onset zone and lesional tissue, as well as in remote regions. These changes occurred in all the investigated pathologies (mesial temporal atrophy/sclerosis, local/regional cortical atrophy, and malformations of cortical development, but were more pronounced in mesial temporal atrophy/sclerosis. Our findings indicate that a brain state change with distinctive features, in the form of unidirectional changes across the entire EEG bandwidth, occurs immediately prior to seizure onset. We postulate that these changes might reflect a facilitating state of the brain which enables a susceptible region to generate seizures.

  20. Focal Segmental Glomerulosclerosis: A Single Center Experience

    Directory of Open Access Journals (Sweden)

    Yavuz Ayar

    2016-09-01

    Full Text Available Aim: Focal segmental glomerulosclerosis (FSGS is one of the most common glomerulonephritis (GNP worldwide. Despite treatment, it may progress to end-stage renal disease. In the present study, we compared clinical and histopathological data on FSGS with primary and secondary GNP retrospectively. Methods: We retrospectively analyzed data on clinical and laboratory findings, treatment response, and risk factors associated with mortality in patients, who had been diagnosed with FSGS and other GNP via renal biopsy between January 2009 and December 2014. The average follow-up time was 22 (8-76 months. Results: FSGS and primary GNP were more frequently seen in males than in females (55.9% vs. 65.3%, p=0.033. Nephrotic syndrome was more common in patients with FSGS (41.2% and primary GNP (57.7%, while chronic renal disease was more frequent in patients with secondary GNP (35%. In FSGS, the complete remission rate was 54.4%. 63.2% of patients had continued to receive treatment. According to the biopsy findings, interstitial inflammation and fibrosis were observed in 100% and 98.5% of patients with FSGS, respectively (p=0.010 and p<0.001, respectively. Serum albumin level was found to be increased and proteinuria, total cholesterol, triglyceride, and LDL levels to be decreased after treatment (p<0.001. Serum creatinine levels and type of GNP (secondary GNP were detected to be 1.48 and 8.14 fold increased in mortality analysis, respectively. Conclusion: Renal biopsy is the gold standard for the diagnosis of glomerular diseases. Renal function at the time of diagnosis, follow-up and appropriate immunosuppressive therapy have effects on mortality and clinical progress in FSGS as is the case in all GNPs.

  1. Focal Length Affects Depicted Shape and Perception of Facial Images.

    Directory of Open Access Journals (Sweden)

    Vít Třebický

    Full Text Available Static photographs are currently the most often employed stimuli in research on social perception. The method of photograph acquisition might affect the depicted subject's facial appearance and thus also the impression of such stimuli. An important factor influencing the resulting photograph is focal length, as different focal lengths produce various levels of image distortion. Here we tested whether different focal lengths (50, 85, 105 mm affect depicted shape and perception of female and male faces. We collected three portrait photographs of 45 (22 females, 23 males participants under standardized conditions and camera setting varying only in the focal length. Subsequently, the three photographs from each individual were shown on screen in a randomized order using a 3-alternative forced-choice paradigm. The images were judged for attractiveness, dominance, and femininity/masculinity by 369 raters (193 females, 176 males. Facial width-to-height ratio (fWHR was measured from each photograph and overall facial shape was analysed employing geometric morphometric methods (GMM. Our results showed that photographs taken with 50 mm focal length were rated as significantly less feminine/masculine, attractive, and dominant compared to the images taken with longer focal lengths. Further, shorter focal lengths produced faces with smaller fWHR. Subsequent GMM revealed focal length significantly affected overall facial shape of the photographed subjects. Thus methodology of photograph acquisition, focal length in this case, can significantly affect results of studies using photographic stimuli perhaps due to different levels of perspective distortion that influence shapes and proportions of morphological traits.

  2. The design of LMJ focal spots for indirect drive experiments

    International Nuclear Information System (INIS)

    Le Garrec, B J; Sajer, J M

    2008-01-01

    LMJ is a 240 high power laser beam facility for achieving laser matter interaction experiments, high energy density science, including the demonstration of fusion ignition through Inertial Confinement. The Laser Integration Line (LIL) facility is currently a 4-beam prototype for LMJ. The intensity I 0 at the focal spot centre drives hydrodynamic and plasma instabilities and the intensity in the wings must be low to go through the laser entrance Hohlraum. A simple model has been developed to compute the LMJ focal spot. The model gives the intensity at the centre as a function of the focal spot area at 3% of the maximum

  3. Focal cemento-osseous dysplasia: review and a case report.

    Science.gov (United States)

    Salem, Y M Y; Osman, Y I; Norval, E J G

    2010-10-01

    Focal cemento-osseous dysplasia is a benign fibro-osseous condition that can be seen in dentate and edentulous patients. It is an asymptomatic lesion and needs no treatment; however follow-up is essential due to the possibility that focal cemento-osseous dysplasia can progress to a condition called florid osseous dysplasia that involves multiple sites. A case report is presented here, along with a review of the differential diagnoses considered in order to reach a final diagnosis of focal cemento-osseous dysplasia.

  4. Benign focal liver lesions: discrimination from malignant mimickers.

    Science.gov (United States)

    Alobaidi, Mohammad; Shirkhoda, Ali

    2004-01-01

    Focal lesions of the liver often have various imaging characteristics which may be interpreted as either benign or malignant. Understanding the underlying pathophysiology of these liver lesions may lead to characteristic imaging manifestations, which direct the radiologist to the diagnosis. Benign lesions include congenital hepatic cyst, autosomal dominant polycystic disease, hemangioma, focal nodular hyperplasia (FNH), hepatic adenoma, inflammatory pseudotumor, peliosis hepatis, focal fatty infiltration, hamartoma, and infectious processes such as hepatic abscess, echinococcal cyst, and candidiasis. Characteristic imaging features, clinical symptoms, and treatment/prognosis will be discussed. Emphasis will be placed on key reliable features of each disease to develop a method of discriminating these lesions from other benign and malignant disorders.

  5. Focused seismicity triggered by flank instability on Kīlauea's Southwest Rift Zone

    Science.gov (United States)

    Judson, Josiah; Thelen, Weston A.; Greenfield, Tim; White, Robert S.

    2018-03-01

    Swarms of earthquakes at the head of the Southwest Rift Zone on Kīlauea Volcano, Hawai´i, reveal an interaction of normal and strike-slip faulting associated with movement of Kīlauea's south flank. A relocated subset of earthquakes between January 2012 and August 2014 are highly focused in space and time at depths that are coincident with the south caldera magma reservoir beneath the southern margin of Kīlauea Caldera. Newly calculated focal mechanisms are dominantly dextral shear with a north-south preferred fault orientation. Two earthquakes within this focused area of seismicity have normal faulting mechanisms, indicating two mechanisms of failure in very close proximity (10's of meters to 100 m). We suggest a model where opening along the Southwest Rift Zone caused by seaward motion of the south flank permits injection of magma and subsequent freezing of a plug, which then fails in a right-lateral strike-slip sense, consistent with the direction of movement of the south flank. The seismicity is concentrated in an area where a constriction occurs between a normal fault and the deeper magma transport system into the Southwest Rift Zone. Although in many ways the Southwest Rift Zone appears analogous to the more active East Rift Zone, the localization of the largest seismicity (>M2.5) within the swarms to a small volume necessitates a different model than has been proposed to explain the lineament outlined by earthquakes along the East Rift Zone.

  6. The intraplate Maranhão earthquake of 2017 January 3, northern Brazil: evidence for uniform regional stresses along the Brazilian equatorial margin

    Science.gov (United States)

    Dias, Fábio L.; Assumpção, M.; Bianchi, Marcelo B.; Barros, Lucas V.; Carvalho, Juraci M.

    2018-04-01

    Lithospheric stresses in intraplate regions can be characterized by many different wavelengths. In some areas, stresses vary over short distances of less than ˜100 km, but in other regions uniform stresses can be recognized for more than ˜1000 km or so. However, not all intraplate regions are well sampled with stress measurements to allow a good characterization of the lithospheric stresses. On 2017 January 3, a magnitude mb 4 earthquake occurred near the equatorial coast of the Maranhão State, an aseismic area of northern Brazil. Despite the few permanent stations in northern Brazil, a well-constrained strike-slip mechanism was obtained from regional moment-tensor inversion. A detailed analysis of the backazimuths of aftershocks recorded by the closest station (˜40 km away) allowed the identification of the fault plane to be the NNW-SSE trending nodal plane. An estimate of the rupture length, about 2 km, was also possible. The strike-slip mechanism has coast-parallel P axis and coast-perpendicular T axis, in agreement with most of the focal mechanisms found further to the east. The coast parallel P axis is also similar to the SHmax orientations from breakouts measurements further along the coast. The Maranhão earthquake fills an important gap of stress indicators in northern Brazil and suggests that the intraplate stress field is uniform along the 2000 km long northern coast.

  7. The 2016 south Alboran earthquake (Mw = 6.4): A reactivation of the Ibero-Maghrebian region?

    Science.gov (United States)

    Buforn, E.; Pro, C.; Sanz de Galdeano, C.; Cantavella, J. V.; Cesca, S.; Caldeira, B.; Udías, A.; Mattesini, M.

    2017-08-01

    On 25 January 2016, an earthquake of magnitude Mw = 6.4 occurred at the southern part of the Alboran Sea, between southern Spain and northern Morocco. This shock was preceded by a foreshock (Mw = 5.1) and followed by a long aftershock sequence. Focal mechanism of main shock has been estimated from slip inversion of body waves at teleseismic distances. Solution corresponds to left-lateral strike-slip motion, showing a complex bilateral rupture, formed by two sub-events, with most energy propagating along a plane oriented N30°E plane dipping to the NW. Relocation of larger events of the aftershock series, show two alignments of epicentres in NE-SW and NNE-SSW direction that intersect at the epicentre of the main shock. We have estimated the focal mechanisms of the largest aftershocks from moment tensor inversion at regional distances. We have obtained two families of focal mechanisms corresponding to strike slip for the NNE-SSW alignment and thrusting motion for the NE-SW alignment. Among the faults present in the area the Al Idrisi fault (or fault zone) may be a good candidate for the source of this earthquake. The study of Coulomb Failure Stress shows that it is possible that the 2016 earthquake was triggered by the previous nearby earthquakes of 1994 (Mw = 5.8) and 2004 (Mw = 6.3). The possible seismic reactivation of the central part of the Ibero-Maghrebian region is an open question, but it is clear that the occurrence of the 2016 earthquake confirms that from 1994 the seismicity of central part of IMR is increasing and that focal mechanism of largest earthquakes in this central part correspond to complex ruptures (or zone of fault).

  8. Unwinding focal segmental glomerulosclerosis [version 1; referees: 3 approved

    Directory of Open Access Journals (Sweden)

    Vasil Peev

    2017-04-01

    Full Text Available Focal segmental glomerulosclerosis (FSGS represents the most common primary glomerular disease responsible for the development of end-stage renal disease (ESRD in the United States (US. The disease progresses from podocyte injury to chronic kidney disease (CKD, ultimately leading to total nephron degeneration. Extensive basic science research has been conducted to unwind the mechanisms of FSGS and, with those insights, understand major contributors of CKD in general. As a result, several putative molecules and pathways have been studied, all implicated in the disease; some serve, in addition, as early biomarkers. The ongoing research is currently focusing on understanding how these molecules and pathways can interplay and be utilized as potential diagnostic and therapeutic targets. Among these molecules, the soluble urokinase plasminogen activating receptor (suPAR has been studied in detail, both clinically and from a basic science perspective. By now, it has emerged as the earliest and most robust marker of future CKD. Other circulating factors harming podocytes include anti-CD40 auto-antibody and possibly cardiotrophin-like cytokine factor-1. Understanding these factors will aid our efforts to ultimately cure FSGS and possibly treat a larger portion of CKD patients much more effectively.

  9. Neuronal network disturbance after focal ischemia in rats

    International Nuclear Information System (INIS)

    Kataoka, K.; Hayakawa, T.; Yamada, K.; Mushiroi, T.; Kuroda, R.; Mogami, H.

    1989-01-01

    We studied functional disturbances following left middle cerebral artery occlusion in rats. Neuronal function was evaluated by [14C]2-deoxyglucose autoradiography 1 day after occlusion. We analyzed the mechanisms of change in glucose utilization outside the infarct using Fink-Heimer silver impregnation, axonal transport of wheat germ agglutinin-conjugated-horseradish peroxidase, and succinate dehydrogenase histochemistry. One day after occlusion, glucose utilization was remarkably reduced in the areas surrounding the infarct. There were many silver grains indicating degeneration of the synaptic terminals in the cortical areas surrounding the infarct and the ipsilateral cingulate cortex. Moreover, in the left thalamus where the left middle cerebral artery supplied no blood, glucose utilization significantly decreased compared with sham-operated rats. In the left thalamus, massive silver staining of degenerated synaptic terminals and decreases in succinate dehydrogenase activity were observed 4 and 5 days after occlusion. The absence of succinate dehydrogenase staining may reflect early changes in retrograde degeneration of thalamic neurons after ischemic injury of the thalamocortical pathway. Terminal degeneration even affected areas remote from the infarct: there were silver grains in the contralateral hemisphere transcallosally connected to the infarct and in the ipsilateral substantia nigra. Axonal transport study showed disruption of the corticospinal tract by subcortical ischemia; the transcallosal pathways in the cortex surrounding the infarct were preserved. The relation between neural function and the neuronal network in the area surrounding the focal cerebral infarct is discussed with regard to ischemic penumbra and diaschisis

  10. Infection-Related Focal Segmental Glomerulosclerosis in Children

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    Anne Katrin Dettmar

    2016-01-01

    Full Text Available Focal segmental glomerulosclerosis (FSGS is the most common cause of steroid resistant nephrotic syndrome in children. It describes a unique histological picture of glomerular damage resulting from several causes. In the majority of patients the causing agent is still unknown, but in some cases viral association is evident. In adults, the most established FSGS causing virus is the human immune-deficiency virus, which is related to a collapsing variant of FSGS. Nevertheless, other viruses are also suspected for causing a collapsing or noncollapsing variant, for example, hepatitis B virus, parvovirus B19, and Cytomegalovirus. Although the systemic infection mechanism is different for these viruses, there are similarities in the pathomechanism for the induction of FSGS. As the podocyte is the key structure in the pathogenesis of FSGS, a direct infection of these cells or immediate damage through the virus or viral components has to be considered. Although viral infections are a very rare cause for FSGS in children, the treating pediatric nephrologist has to be aware of a possible underlying infection, as this has a relevant impact on therapy and prognosis.

  11. Dual-layer electrode-driven liquid crystal lens with electrically tunable focal length and focal plane

    Science.gov (United States)

    Zhang, Y. A.; Lin, C. F.; Lin, J. P.; Zeng, X. Y.; Yan, Q.; Zhou, X. T.; Guo, T. L.

    2018-04-01

    Electric-field-driven liquid crystal (ELC) lens with tunable focal length and their depth of field has been extensively applied in 3D display and imaging systems. In this work, a dual-layer electrode-driven liquid crystal (DELC) lens with electrically tunable focal length and controllable focal plane is demonstrated. ITO-SiO2-AZO electrodes with the dual-layer staggered structure on the top substrate are used as driven electrodes within a LC cell, which permits the establishment of an alternative controllability. The focal length of the DELC lens can be adjusted from 1.41 cm to 0.29 cm when the operating voltage changes from 15 V to 40 V. Furthermore, the focal plane of the DELC lens can selectively move by changing the driving method of the applied voltage to the next driven electrodes. This work demonstrates that the DELC lens has potential applications in imaging systems because of electrically tunable focal length and controllable focal plane.

  12. Experimental focal neocortical epilepsy is associated with reduced white matter volume growth : results from multiparametric MRI analysis

    NARCIS (Netherlands)

    Otte, Wim; van Meer, Maurits P A; van der Marel, Kajo; Zwartbol, René; Viergever, Max A.; Braun, Kees P J; Dijkhuizen, Rick M.

    2015-01-01

    Focal epilepsy has recently been associated with remote white matter damage, including reduced white matter volume. Longitudinal assessment of these white matter changes, in relation to functional mechanisms and consequences, may be ideally done by in vivo neuroimaging in well-controlled

  13. Angiogenin enhances cell migration by regulating stress fiber assembly and focal adhesion dynamics.

    Directory of Open Access Journals (Sweden)

    Saisai Wei

    Full Text Available Angiogenin (ANG acts on both vascular endothelial cells and cancer cells, but the underlying mechanism remains elusive. In this study, we carried out a co-immunoprecipitation assay in HeLa cells and identified 14 potential ANG-interacting proteins. Among these proteins, β-actin, α-actinin 4, and non-muscle myosin heavy chain 9 are stress fiber components and involved in cytoskeleton organization and movement, which prompted us to investigate the mechanism of action of ANG in cell migration. Upon confirmation of the interactions between ANG and the three proteins, further studies revealed that ANG co-localized with β-actin and α-actinin 4 at the leading edge of migrating cells. Down-regulation of ANG resulted in fewer but thicker stress fibers with less dynamics, which was associated with the enlargements of focal adhesions. The focal adhesion kinase activity and cell migration capacity were significantly decreased in ANG-deficient cells. Taken together, our data demonstrated that the existence of ANG in the cytoplasm optimizes stress fiber assembly and focal adhesion formation to accommodate cell migration. The finding that ANG promoted cancer cell migration might provide new clues for tumor metastasis research.

  14. EFFICACY OF RUFINAMIDE IN THE TREATMENT OF DRUG-RESISTANT FOCAL EPILEPSIES IN PAEDIATRIC PRACTICE

    Directory of Open Access Journals (Sweden)

    I. O. Shchederkina

    2016-01-01

    Full Text Available Among drug-resistant epilepsies, epileptic syndromes, characterized by combination of several types of seizures, are considered to be the most difficult in terms of treatment. Lennox–Gastaut syndrome is one of them. It manifests with polymorphic seizures (tonic axial, myatonic, atypical absence seizures, status epilepticus of minor motor seizures, myoclonic, generalized convulsive, and focal seizures. This is a heterogeneous disease, represented by a complex of clinical and electroencephalographic manifestations with various etiology. Current review is devoted to a novel antiepileptic drug rufinamide, which has a new mechanism of action. The drug has been registered in Russia in 2015. The authors also describe their own experience of rufinamide usage in the treatment of drug-resistant focal epilepsy as a part of multicomponent therapy for polymorphic seizures. One patient achieved clinical remission for 16 months; the second one had more than 50 % decrease in seizures frequency with a remission of drop-attacks.

  15. DEPDC5 takes a second hit in familial focal epilepsy.

    Science.gov (United States)

    Anderson, Matthew P

    2018-04-30

    Loss-of-function mutations in a single allele of the gene encoding DEP domain-containing 5 protein (DEPDC5) are commonly linked to familial focal epilepsy with variable foci; however, a subset of patients presents with focal cortical dysplasia that is proposed to result from a second-hit somatic mutation. In this issue of the JCI, Ribierre and colleagues provide several lines of evidence to support second-hit DEPDC5 mutations in this disorder. Moreover, the authors use in vivo, in utero electroporation combined with CRISPR-Cas9 technology to generate a murine model of the disease that recapitulates human manifestations, including cortical dysplasia-like changes, focal seizures, and sudden unexpected death. This study provides important insights into familial focal epilepsy and provides a preclinical model for evaluating potential therapies.

  16. Managing focal fields of vector beams with multiple polarization singularities.

    Science.gov (United States)

    Han, Lei; Liu, Sheng; Li, Peng; Zhang, Yi; Cheng, Huachao; Gan, Xuetao; Zhao, Jianlin

    2016-11-10

    We explore the tight focusing behavior of vector beams with multiple polarization singularities, and analyze the influences of the number, position, and topological charge of the singularities on the focal fields. It is found that the ellipticity of the local polarization states at the focal plane could be determined by the spatial distribution of the polarization singularities of the vector beam. When the spatial location and topological charge of singularities have even-fold rotation symmetry, the transverse fields at the focal plane are locally linearly polarized. Otherwise, the polarization state becomes a locally hybrid one. By appropriately arranging the distribution of the polarization singularities in the vector beam, the polarization distributions of the focal fields could be altered while the intensity maintains unchanged.

  17. Focal myositis of lower extremity responsive to botulinum A toxin.

    Science.gov (United States)

    Mitrovic, Josko; Prka, Zeljko; Zic, Rado; Marusic, Srecko; Morovic-Vergles, Jadranka

    2014-01-01

    Focal myositis is a rare, mostly benign disease (pseudotumor) of skeletal muscle, histopathologically characterized by interstitial myositis and tumorous enlargement of a single muscle. The etiology of focal myositis remains unknown; however, localized myopathy has been postulated to be caused by denervation lesions. This case report describes a patient that presented with clinical, laboratory, electromyoneurography, and magnetic resonance imaging features of focal myositis complicated with intervertebral disk protrusion in the lumbosacral spine affected with radicular distress. In most cases, focal myositic lesions show spontaneous regression, relapses are rare, and long-term prognosis is good. There is a wide spectrum of therapeutic options, from no therapy at all through nonsteroidal antirheumatics and glucocorticoids to radiotherapy, surgical excision, and immunosuppressants. In the patient presented, treatment with glucocorticoids, methotrexate, and surgical excision failed to produce satisfactory results. Clinical improvement, pain relief, and reduction in lower leg volume were only achieved by local infiltration of botulinum A toxin.

  18. FOCAL CORTICAL DYSPLASIAS: CLINICAL AND ELECTRO-NEUROIMAGING CHARACTERISTICS

    Directory of Open Access Journals (Sweden)

    K. Yu. Mukhin

    2016-01-01

    Full Text Available In spite of a notable advance made in epileptology, resistant epilepsies account for approximately 30 % of all forms of epilepsy particularly in patients with focal seizures. One of the main causes of therapy-resistant focal epilepsies is focal cortical dysplasias (FCD. This term was first introduced by D. Taylor et al. in 1971. FCD belongs to abnormal cortical development. Among all abnormalities of cortical development, FCD in surgically treated children amounts to 75 %. FCD is the most common cause of resistant epilepsy in children and the most frequent reason for diagnosing cryptogenic focal epilepsy with intractable seizures. The author gives a detailed literature review dedicated to FCD as a cause of resistant epilepsy, including the classification and histologic characteristics of FCD, its clinical manifestations and prognosis, and approaches to medical and surgical treatments. 

  19. Electrocorticographic discharge patterns in glioneuronal tumors and focal cortical dysplasia

    NARCIS (Netherlands)

    Ferrier, Cyrille H.; Aronica, Eleanora; Leijten, Frans S. S.; Spliet, Wim G. M.; van Huffelen, Alexander C.; van Rijen, Peter C.; Binnie, Colin D.

    2006-01-01

    PURPOSE: To determine whether highly epileptiform electrocorticographical discharge patterns occur in patients with glioneuronal tumors (GNTs) and focal cortical dysplasia (FCD) and whether specific histopathological features are related to such patterns. METHODS: The series consists of operated

  20. Adult-onset Rasmussen encephalitis associated with focal cortical dysplasia.

    Science.gov (United States)

    Hohenbichler, Katharina; Lelotte, Julie; Lhommel, Renaud; Tahry, Riëm El; Vrielynck, Pascal; Santos, Susana Ferrao

    2017-12-01

    Rasmussen encephalitis is a rare, devastating condition, typically presenting in childhood. Cases of adult-onset Rasmussen have also been described, but the clinical picture is less defined, rendering final diagnosis difficult. We present a case of adult-onset Rasmussen encephalitis with dual pathology, associated with focal cortical dysplasia and encephalitis. We interpreted the Rasmussen encephalitis to be caused by severe and continuous epileptic activity due to focal cortical dysplasia. The best therapeutic approach for such cases remains unclear.

  1. Focal plane for the next generation of earth observation instruments

    Science.gov (United States)

    Pranyies, P.; Toubhans, I.; Badoil, B.; Tanguy, F.; Descours, Francis

    2017-09-01

    Sodern is the French focal plane provider for Earth Observation (EO) satellites. Since the 1980's, Sodern has played an active role first in the SPOT program. Within the two-spacecraft constellation Pleiades 1A/1B over the next years, Sodern introduced advanced technologies as Silicon Carbide (SiC) focal plane structure and multispectral strip filters dedicated to multiple-lines detectors.

  2. Earthquake source parameters along the Hellenic subduction zone and numerical simulations of historical tsunamis in the Eastern Mediterranean

    Science.gov (United States)

    Yolsal-Çevikbilen, Seda; Taymaz, Tuncay

    2012-04-01

    We studied source mechanism parameters and slip distributions of earthquakes with Mw ≥ 5.0 occurred during 2000-2008 along the Hellenic subduction zone by using teleseismic P- and SH-waveform inversion methods. In addition, the major and well-known earthquake-induced Eastern Mediterranean tsunamis (e.g., 365, 1222, 1303, 1481, 1494, 1822 and 1948) were numerically simulated and several hypothetical tsunami scenarios were proposed to demonstrate the characteristics of tsunami waves, propagations and effects of coastal topography. The analogy of current plate boundaries, earthquake source mechanisms, various earthquake moment tensor catalogues and several empirical self-similarity equations, valid for global or local scales, were used to assume conceivable source parameters which constitute the initial and boundary conditions in simulations. Teleseismic inversion results showed that earthquakes along the Hellenic subduction zone can be classified into three major categories: [1] focal mechanisms of the earthquakes exhibiting E-W extension within the overriding Aegean plate; [2] earthquakes related to the African-Aegean convergence; and [3] focal mechanisms of earthquakes lying within the subducting African plate. Normal faulting mechanisms with left-lateral strike slip components were observed at the eastern part of the Hellenic subduction zone, and we suggest that they were probably concerned with the overriding Aegean plate. However, earthquakes involved in the convergence between the Aegean and the Eastern Mediterranean lithospheres indicated thrust faulting mechanisms with strike slip components, and they had shallow focal depths (h < 45 km). Deeper earthquakes mainly occurred in the subducting African plate, and they presented dominantly strike slip faulting mechanisms. Slip distributions on fault planes showed both complex and simple rupture propagations with respect to the variation of source mechanism and faulting geometry. We calculated low stress drop

  3. Reassessment of source parameters for three major earthquakes in the East African rift system from historical seismograms and bulletins

    Directory of Open Access Journals (Sweden)

    O. Kulhánek

    2000-06-01

    Full Text Available Source parameters for three majo earthquakes in the East African rift are re-computed from historical seismograms and bulletins. The main shock and the largest foreshock of the August 25, 1906 earthquake sequence in the main Ethiopian rift are re-located on the eastern shoulder of the rift segment.The magnitude of the main shock is estimated to be 6.5 (Mw from spectral analysis. The December 13, 1910 earthquake in the Rukwa rift (Western Tanzania indicated a significant strike-slip component from teleseismcs body-waveform inversion for fault mechanism and seismic moment. The January 6, 1928 earthquake in the Gregory rift (Kenya showed a multiple rupture process and unusually long duration for a size of 6.6(Mw. The May 20, 1990 earthquake in Southern Sudan, mentioned merely for the sake of comparison, is the largest of all instrumentally recorded events in the East African rift system. Despite the fact that the mode of deformation in the continental rift is predominantly of extensional nature, the three largest earthquakes known to occur in the circum-Tanzanian craton have shallow focal depths and significant strike-slip component in their fault mechanisms. This and similar works will enrich the database for seismic hazard assessment in East Africa.

  4. Microseismicity at the North Anatolian Fault in the Sea of Marmara offshore Istanbul, NW Turkey

    Science.gov (United States)

    Bulut, Fatih; Bohnhoff, Marco; Ellsworth, William L.; Aktar, Mustafa; Dresen, Georg

    2009-01-01

    The North Anatolian Fault Zone (NAFZ) below the Sea of Marmara forms a “seismic gap” where a major earthquake is expected to occur in the near future. This segment of the fault lies between the 1912 Ganos and 1999 İzmit ruptures and is the only NAFZ segment that has not ruptured since 1766. To monitor the microseismic activity at the main fault branch offshore of Istanbul below the Çınarcık Basin, a permanent seismic array (PIRES) was installed on the two outermost Prince Islands, Yassiada and Sivriada, at a few kilometers distance to the fault. In addition, a temporary network of ocean bottom seismometers was deployed throughout the Çınarcık Basin. Slowness vectors are determined combining waveform cross correlation and P wave polarization. We jointly invert azimuth and traveltime observations for hypocenter determination and apply a bootstrap resampling technique to quantify the location precision. We observe seismicity rates of 20 events per month for M etermine composite focal mechanisms implementing recordings of surrounding permanent land stations. Fault plane solutions have a predominant right-lateral strike-slip mechanism, indicating that normal faulting along this part of the NAFZ plays a minor role. Toward the west we observe increasing components of thrust faulting. This supports the model of NW trending, dextral strike-slip motion along the northern and main branch of the NAFZ below the eastern Sea of Marmara.

  5. Inverse-designed stretchable metalens with tunable focal distance

    Science.gov (United States)

    Callewaert, Francois; Velev, Vesselin; Jiang, Shizhou; Sahakian, Alan Varteres; Kumar, Prem; Aydin, Koray

    2018-02-01

    In this paper, we present an inverse-designed 3D-printed all-dielectric stretchable millimeter wave metalens with a tunable focal distance. A computational inverse-design method is used to design a flat metalens made of disconnected polymer building blocks with complex shapes, as opposed to conventional monolithic lenses. The proposed metalens provides better performance than a conventional Fresnel lens, using lesser amount of material and enabling larger focal distance tunability. The metalens is fabricated using a commercial 3D-printer and attached to a stretchable platform. Measurements and simulations show that the focal distance can be tuned by a factor of 4 with a stretching factor of only 75%, a nearly diffraction-limited focal spot, and with a 70% relative focusing efficiency, defined as the ratio between power focused in the focal spot and power going through the focal plane. The proposed platform can be extended for design and fabrication of multiple electromagnetic devices working from visible to microwave radiation depending on scaling of the devices.

  6. Blaschko Linear Enamel Defects - A Marker for Focal Dermal Hypoplasia: Case Report of Focal Dermal Hypoplasia

    Directory of Open Access Journals (Sweden)

    Stefan Gysin

    2015-05-01

    Full Text Available Focal dermal hypoplasia (FDH is a rare genetic skin disorder. The inheritance of FDH or Goltz-Gorlin syndrome is X-linked dominant and the disease is associated with a PORCN gene mutation. This gene plays a key role in the Wnt pathway, which has an impact on embryonic development. Every tissue derived from meso- and ectoderm can be affected. Patients suffer from cutaneous, ocular, osseous, oral and dental defects. The skin and dental alterations manifest along the Blaschko lines. We present a woman (born in 1962 suffering from FDH with congenital skin changes and Blaschko linear enamel defects. Typical symptoms (e.g. fat herniations, scoliosis, syndactyly, microphthalmia, caries and alopecia plus vertical grooving of all teeth gave a first indication. Molecular genetic testing confirmed the definitive diagnosis of FDH. We hypothesize that, in the context of typical skin changes, visible Blaschko lines on the teeth in the form of vertical grooves are almost pathognomonic for FDH.

  7. Extensional Tectonics of SW Anatolia In relation to Slab Edge Processes in the Eastern Mediterranean

    Science.gov (United States)

    Kaymakci, N.; Özacar, A.; Langereis, C. G.; Ozkaptan, M.; Koç, A.; Uzel, B.; Gulyuz, E.; Sözbilir, H.

    2017-12-01

    The tectonics of SW Anatolia is expressed in terms of emplacement of Lycian Nappes during the Eocene to Middle Miocene and synconvergent extension as part of the Aegean-West Anatolian extensional tectonic regime. Recent studies identified that there is a tear in the northwards subducting African Oceanic lithosphere along the Pliny-Strabo Trenches (PST). Such tears are coined as Subduction Transform-Edge Propagator (STEP) faults developed high angle to trenches. Hypothetically, the evolution of a STEP fault is somewhat similar to strike-slip fault zones and resultant asymmetric role-back of the subducting slab leads to differential block rotations and back arc type extension on the overriding plate. Recent studies claimed that the tear along the PST propagated NE on-land and developed Fethiye-Burdur Fault/Shear Zone (FBFZ) in SW Turkey. We have conducted a rigorous paleomagnetic study containing more than 3000 samples collected from 88 locations and 11700 fault slip data sets from 198 locations distributed evenly all over SW Anatolia spanning from Middle Miocene to Late Pliocene to test if FBFZ ever existed. The results show that there is slight (20°) counter-clockwise rotation distributed uniformly almost whole SW Anatolia and there is no change in the rotation senses and amounts on either side of the FBFZ implying no differential rotation within the zone. Additionally, constructed paleostress configurations, along the so-called FBFZ and within the 300 km diameter of the proposed fault zone, indicated that almost all the faults that are parallel to subparallel to the zone are almost pure normal faults similar to earthquake focal mechanisms suggesting active extension in the region. It is important to note that we have not encountered any significant strike-slip motion parallel to so-called "FBFZ" to support presence and transcurrent nature of it. On the contrary, the region is dominated by extensional deformation and strike-slip components are observed only on the

  8. Style and rate of quaternary deformation of the Hosgri Fault Zone, offshore south-central coastal California

    Science.gov (United States)

    Hanson, Kathryn L.; Lettis, William R.; McLaren, Marcia; Savage, William U.; Hall, N. Timothy; Keller, Mararget A.

    2004-01-01

    The Hosgri Fault Zone is the southernmost component of a complex system of right-slip faults in south-central coastal California that includes the San Gregorio, Sur, and San Simeon Faults. We have characterized the contemporary style of faulting along the zone on the basis of an integrated analysis of a broad spectrum of data, including shallow high-resolution and deep penetration seismic reflection data; geologic and geomorphic data along the Hosgri and San Simeon Fault Zones and the intervening San Simeon/Hosgri pull-apart basin; the distribution and nature of near-coast seismicity; regional tectonic kinematics; and comparison of the Hosgri Fault Zone with worldwide strike-slip, oblique-slip, and reverse-slip fault zones. These data show that the modern Hosgri Fault Zone is a convergent right-slip (transpressional) fault having a late Quaternary slip rate of 1 to 3 mm/yr. Evidence supporting predominantly strike-slip deformation includes (1) a long, narrow, linear zone of faulting and associated deformation; (2) the presence of asymmetric flower structures; (3) kinematically consistent localized extensional and compressional deformation at releasing and restraining bends or steps, respectively, in the fault zone; (4) changes in the sense and magnitude of vertical separation both along trend of the fault zone and vertically within the fault zone; (5) strike-slip focal mechanisms along the fault trace; (6) a distribution of seismicity that delineates a high-angle fault extending through the seismogenic crust; (7) high ratios of lateral to vertical slip along the fault zone; and (8) the separation by the fault of two tectonic domains (offshore Santa Maria Basin, onshore Los Osos domain) that are undergoing contrasting styles of deformation and orientations of crustal shortening. The convergent component of slip is evidenced by the deformation of the early-late Pliocene unconformity. In characterizing the style of faulting along the Hosgri Fault Zone, we assessed

  9. On the physical links between the dynamics of the Izu Islands 2000 dike intrusions and the statistics of the induced seismicity

    Science.gov (United States)

    Passarelli, Luigi; Rivalta, Eleonora; Simone, Cesca; Aoki, Yosuke

    2014-05-01

    The emplacement of magma-filled dikes often induce abundant seismicity in the surrounding host rocks. Most of the earthquakes are thought to occur close to the propagating tip (or edges, in 3D) of the dike, where stresses are concentrated. The resulting seismicity often appears as a swarm, controlled mainly by dike-induced stresses and stressing rate and by other factors, such as the background stressing rate, tectonic setting, regional stresses and tectonic history. The spatial distribution and focal mechanisms of the seismicity bear information on the interaction of the dike stress field and the tectonic setting of the area. The seismicity accompanying the intrusion of a dike is usually characterized by weak events, for which it is difficult to calculate the focal mechanisms. Therefore, only for a few well-recorded dike intrusions a catalog of focal mechanisms, allowing to perform a robust statistical analysis, is available. The 2000 dike intrusion at Miyakejima is in this sense an outstanding case, as about 18000 seismic events were recorded in a time span of three months. This seismic swarm was one of the most energetic ever recorded with five M>6 earthquakes. For this swarm a catalog of 1500 focal mechanisms is avalable (NIED, Japan). We perform a clustering analysis of the focal mechanism solutions, in order to infer the most frequent focal mechanism features prior to the intrusion (pre-diking period) and during the co-diking period. As previously suggested, we find that the dike stress field modified substantially the pre-existing seismicity pattern, by shadowing some non-optimally oriented strike-slip structures and increasing seismic rate on optimally oriented strike-slip tectonic structures. Alongside, during the co-diking period a large number of normal and oblique-normal faulting were observed. These events cannot be explained within the tectonics of the intrusion area. We suggest they are directly generated by the intense stress field induced at the

  10. Dentistry and internal medicine: from the focal infection theory to the periodontal medicine concept.

    Science.gov (United States)

    Pizzo, Giuseppe; Guiglia, Rosario; Lo Russo, Lucio; Campisi, Giuseppina

    2010-12-01

    During past decades the relationship between dentistry and internal medicine and especially the concept of the so-called focal infection theory have long been a matter of debate. The pathogenesis of focal diseases has been classically attributed to dental pulp pathologies and periapical infections. Nonetheless, in recent years, their role is being dismissed while increasing interest is being devoted to the possible associations between periodontal infection and systemic diseases. In fact, periodontal pathogens and their products, as well as inflammatory mediators produced in periodontal tissues, might enter the bloodstream, causing systemic effects and/or contributing to systemic diseases. On the basis of this mechanism, chronic periodontitis has been suggested as a risk factor for cardiovascular diseases associated with atherosclerosis, bacterial endocarditis, diabetes mellitus, respiratory disease, preterm delivery, rheumatoid arthritis, and, recently, osteoporosis, pancreatic cancer, metabolic syndrome, renal diseases and neurodegenerative diseases such as Alzheimer's disease. Various hypotheses, including common susceptibility, systemic inflammation, direct bacterial infection and cross-reactivity, or molecular mimicry, between bacterial antigens and self-antigens, have been postulated to explain these relationships. In this scenario, the association of periodontal disease with systemic diseases has set the stage for introducing the concept of periodontal medicine. This narrative review summarizes the evolution of focal infection theory up to the current pathophysiology of periodontal disease, and presents an update on the relationships between chronic periodontitis and systemic diseases. Copyright © 2010 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

  11. Electroacupuncture pretreatment induces tolerance against focal cerebral ischemia through activation of canonical Notch pathway

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    Zhao Yu

    2012-09-01

    Full Text Available Abstract Background Electroacupuncture (EA pretreatment can induce the tolerance against focal cerebral ischemia. However, the underlying mechanisms have not been fully understood. Emerging evidences suggest that canonical Notch signaling may be involved in ischemic brain injury. In the present study, we tested the hypothesis that EA pretreatment-induced tolerance against focal cerebral ischemia is mediated by Notch signaling. Results EA pretreatment significantly enhanced Notch1, Notch4 and Jag1 gene transcriptions in the striatum, except Notch1 intracellular domain level, which could be increased evidently by ischemia. After ischemia and reperfusion, Hes1 mRNA and Notch1 intracellular domain level in ischemic striatum in EA pretreatment group were increased and reached the peak at 2 h and 24 h, respectively, which were both earlier than the peak achieved in control group. Intraventricular injection with the γ-secretase inhibitor MW167 attenuated the neuroprotective effect of EA pretreatment. Conclusions EA pretreatment induces the tolerance against focal cerebral ischemia through activation of canonical Notch pathway.

  12. FAK dimerization controls its kinase-dependent functions at focal adhesions

    KAUST Repository

    Brami-Cherrier, Karen; Gervasi, Nicolas; Arsenieva, Diana A.; Walkiewicz, Katarzyna; Boutterin, Marie Claude; Ortega, Á lvaro Darí o; Leonard, Paul G.; Seantier, Bastien; Gasmi, Laï la; Bouceba, Tahar; Kadaré , Gress; Girault -, Jean Antoine; Arold, Stefan T.

    2014-01-01

    Focal adhesion kinase (FAK) controls adhesion-dependent cell motility, survival, and proliferation. FAK has kinase-dependent and kinase-independent functions, both of which play major roles in embryogenesis and tumor invasiveness. The precise mechanisms of FAK activation are not known. Using x-ray crystallography, small angle x-ray scattering, and biochemical and functional analyses, we show that the key step for activation of FAK's kinase-dependent functions-autophosphorylation of tyrosine-397-requires site-specific dimerization of FAK. The dimers form via the association of the N-terminal FERM domain of FAK and are stabilized by an interaction between FERM and the C-terminal FAT domain. FAT binds to a basic motif on FERM that regulates co-activation and nuclear localization. FAK dimerization requires local enrichment, which occurs specifically at focal adhesions. Paxillin plays a dual role, by recruiting FAK to focal adhesions and by reinforcing the FAT:FERM interaction. Our results provide a structural and mechanistic framework to explain how FAK combines multiple stimuli into a site-specific function. The dimer interfaces we describe are promising targets for blocking FAK activation. © 2014 The Authors.

  13. FAK dimerization controls its kinase-dependent functions at focal adhesions

    KAUST Repository

    Brami-Cherrier, Karen

    2014-01-30

    Focal adhesion kinase (FAK) controls adhesion-dependent cell motility, survival, and proliferation. FAK has kinase-dependent and kinase-independent functions, both of which play major roles in embryogenesis and tumor invasiveness. The precise mechanisms of FAK activation are not known. Using x-ray crystallography, small angle x-ray scattering, and biochemical and functional analyses, we show that the key step for activation of FAK\\'s kinase-dependent functions-autophosphorylation of tyrosine-397-requires site-specific dimerization of FAK. The dimers form via the association of the N-terminal FERM domain of FAK and are stabilized by an interaction between FERM and the C-terminal FAT domain. FAT binds to a basic motif on FERM that regulates co-activation and nuclear localization. FAK dimerization requires local enrichment, which occurs specifically at focal adhesions. Paxillin plays a dual role, by recruiting FAK to focal adhesions and by reinforcing the FAT:FERM interaction. Our results provide a structural and mechanistic framework to explain how FAK combines multiple stimuli into a site-specific function. The dimer interfaces we describe are promising targets for blocking FAK activation. © 2014 The Authors.

  14. Source parameters of the M 6.5 Skyros Island (North Aegean Sea earthquake of July 26, 2001

    Directory of Open Access Journals (Sweden)

    A. Kiratzi

    2002-06-01

    Full Text Available Teleseismic body wave modelling, time domain moment tensor inversion of regional waveforms and spectral analysis of the far-field P-wave pulses are used to derive the source parameters of the July 26, 2001 Skyros earthquake (M 6.5. Its epicentre is located south of the Sporades Islands in the North Aegean Sea (Greece. Previous focal mechanism solutions indicate motion on strike-slip faults. The time domain moment tensor inversion is applied for the first time to the regional waveforms of the recently established broadband network in Greece. Its application gave results which are highly consistent with teleseismic waveform modelling. The results of this study, in combination with the distribution of aftershocks, indicate left-lateral strike slip motion on a NW-SE striking fault with parameters: fault plane (strike = 151°, dip = 83°, rake = 7° and auxiliary plane (strike = 60°, dip = 84°, rake = 173°, depth 12 km and M 0 = 5.98e18 N m. Moreover, the time domain moment tensor inversion technique yielded a pure double couple source with negligible CLVD. The spectral analysis of the far-field P-wave pulses resulted in a fault length L ~ 32 km, stress drop ~ 9 bars and average displacement u ~ 30 cm.These values are in very good agreement with those estimated from empirical scaling relations applicable to the Aegean area.

  15. Multispecies, Integrative GWAS for Focal Segmental Glomerulosclerosis

    Science.gov (United States)

    2017-09-01

    searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments...is a frequent cause of end-stage renal disease (ESRD. We investigated the genetic basis of FSGS and recruited a heterogeneous population of...understanding the complex genetic mechanisms of FSGS. 15. SUBJECT TERMS FSGS, MCD, GWAS, CNV  16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT uu

  16. Reversed Procrastination by Focal Disruption of Medial Frontal Cortex.

    Science.gov (United States)

    Jha, Ashwani; Diehl, Beate; Scott, Catherine; McEvoy, Andrew W; Nachev, Parashkev

    2016-11-07

    An enduring puzzle in the neuroscience of voluntary action is the origin of the remarkably wide dispersion of the reaction time distribution, an interval far greater than is explained by synaptic or signal transductive noise [1, 2]. That we are able to change our planned actions-a key criterion of volition [3]-so close to the time of their onset implies decision-making must reach deep into the execution of action itself [4-6]. It has been influentially suggested the reaction time distribution therefore reflects deliberate neural procrastination [7], giving alternative response tendencies sufficient time for fair competition in pursuing a decision threshold that determines which one is behaviorally manifest: a race model, where action selection and execution are closely interrelated [8-11]. Although the medial frontal cortex exhibits a sensitivity to reaction time on functional imaging that is consistent with such a mechanism [12-14], direct evidence from disruptive studies has hitherto been lacking. If movement-generating and movement-delaying neural substrates are closely co-localized here, a large-scale lesion will inevitably mask any acceleration, for the movement itself could be disrupted. Circumventing this problem, here we observed focal intracranial electrical disruption of the medial frontal wall in the context of the pre-surgical evaluation of two patients with epilepsy temporarily reversing such hypothesized procrastination. Effector-specific behavioral acceleration, time-locked to the period of electrical disruption, occurred exclusively at a specific locus at the ventral border of the pre-supplementary motor area. A cardinal prediction of race models of voluntary action is thereby substantiated in the human brain. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  17. Computational model of neuron-astrocyte interactions during focal seizure generation

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    Davide eReato

    2012-10-01

    Full Text Available Empirical research in the last decade revealed that astrocytes can respond to neurotransmitters with Ca2+ elevations and generate feedback signals to neurons which modulate synaptic transmission and neuronal excitability. This discovery changed our basic understanding of brain function and provided new perspectives for how astrocytes can participate not only to information processing, but also to the genesis of brain disorders, such as epilepsy. Epilepsy is a neurological disorder characterized by recurrent seizures that can arise focally at restricted areas and propagate throughout the brain. Studies in brain slice models suggest that astrocytes contribute to epileptiform activity by increasing neuronal excitability through a Ca2+-dependent release of glutamate. The underlying mechanism remains, however, unclear. In this study, we implemented a parsimonious network model of neurons and astrocytes. The model consists of excitatory and inhibitory neurons described by Izhikevich's neuron dynamics. The experimentally observed Ca2+ change in astrocytes in response to neuronal activity was modeled with linear equations. We considered that glutamate is released from astrocytes above certain intracellular Ca2+ concentrations thus providing a non-linear positive feedback signal to neurons. Propagating seizure-like ictal discharges (IDs were reliably evoked in our computational model by repeatedly exciting a small area of the network, which replicates experimental results in a slice model of focal ID in entorhinal cortex. We found that the threshold of focal ID generation was lowered when an excitatory feedback-loop between astrocytes and neurons was included. Simulations show that astrocytes can contribute to ID generation by directly affecting the excitatory/inhibitory balance of the neuronal network. Our model can be used to obtain mechanistic insights into the distinct contributions of the different signaling pathways to the generation and

  18. Focal Plane Alignment Utilizing Optical CMM

    Science.gov (United States)

    Liebe, Carl Christian; Meras, Patrick L.; Clark, Gerald J.; Sedaka, Jack J.; Kaluzny, Joel V.; Hirsch, Brian; Decker, Todd A.; Scholtz, Christopher R.

    2012-01-01

    In many applications, an optical detector has to be located relative to mechanical reference points. One solution is to specify stringent requirements on (1) mounting the optical detector relative to the chip carrier, (2) soldering the chip carrier onto the printed circuit board (PCB), and (3) installing the PCB to the mechanical structure of the subsystem. Figure 1 shows a sketch of an optical detector mounted relative to mechanical reference with high positional accuracy. The optical detector is typically a fragile wafer that cannot be physically touched by any measurement tool. An optical coordinate measuring machine (CMM) can be used to position optical detectors relative to mechanical reference points. This approach will eliminate all requirements on positional tolerances. The only requirement is that the PCB is manufactured with oversized holes. An exaggerated sketch of this situation is shown in Figure 2. The sketch shows very loose tolerances on mounting the optical detector in the chip carrier, loose tolerance on soldering the chip carrier to the PCB, and finally large tolerance on where the mounting screws are located. The PCB is held with large screws and oversized holes. The PCB is mounted loosely so it can move freely around. The optical CMM measures the mechanical reference points. Based on these measurements, the required positions of the optical detector corners can be calculated. The optical CMM is commanded to go to the position where one detector corner is supposed to be. This is indicated with the cross-hairs in Figure 2(a). This figure is representative of the image of the optical CMM monitor. Using a suitable tapping tool, the PCB is manually tapped around until the corner of the optical detector is at the crosshairs of the optical CMM. The CMM is commanded to another corner, and the process is repeated a number of times until all corners of the optical detector are within a distance of 10 to 30 microns of the required position. The situation

  19. CT findings of focal organizing pneumonia: correlation with pathologic findings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yang Soo; Kim, Young Goo; Park, Un Sup [College of Medicine, Chungang University, Seoul (Korea, Republic of)

    1994-11-15

    To evaluate the CT findings of focal organizing pneumonia and to correlate them with pathologic findings to help differentiating from lung cancer. We evaluated radiologic and pathologic findings of five patients with solitary pulmonary nodule which were confirmed as focal organizing pneumonia pathologically. On CT scan, focal organizing pneumonia had irregular margin contacting the pleura in all five cases. The shape of the nodules were spherical to wedge or elliptical and the size from 3.5cm to 5.5cm(average 4.2 cm) in largest diameter. On postcontrast CT scan, all nodules showed enhancement and four cases showed central low density components. Two nodules contained air within the nodule. In four cases, pleural changes such as effusion and/or focal thickening were noted. No lymphadenopathy was found in all cases. Pathologically, the enhancing portion on CT showed findings of organizing pneumonia such as granulation tissue with fibroblast proliferation in alveolar space and interstitial thickening. The central low density areas on CT were due to ischemic necrosis, abscess and exudate, transudate and infiltration of foamy histiocyte. The possibility of focal organizing pneumonia should be considered when peripherally located solitary pulmonary nodule had enhancing component with no combined lymphadenopathy on CT scan.

  20. CT findings of focal organizing pneumonia: correlation with pathologic findings

    International Nuclear Information System (INIS)

    Kim, Yang Soo; Kim, Young Goo; Park, Un Sup

    1994-01-01

    To evaluate the CT findings of focal organizing pneumonia and to correlate them with pathologic findings to help differentiating from lung cancer. We evaluated radiologic and pathologic findings of five patients with solitary pulmonary nodule which were confirmed as focal organizing pneumonia pathologically. On CT scan, focal organizing pneumonia had irregular margin contacting the pleura in all five cases. The shape of the nodules were spherical to wedge or elliptical and the size from 3.5cm to 5.5cm(average 4.2 cm) in largest diameter. On postcontrast CT scan, all nodules showed enhancement and four cases showed central low density components. Two nodules contained air within the nodule. In four cases, pleural changes such as effusion and/or focal thickening were noted. No lymphadenopathy was found in all cases. Pathologically, the enhancing portion on CT showed findings of organizing pneumonia such as granulation tissue with fibroblast proliferation in alveolar space and interstitial thickening. The central low density areas on CT were due to ischemic necrosis, abscess and exudate, transudate and infiltration of foamy histiocyte. The possibility of focal organizing pneumonia should be considered when peripherally located solitary pulmonary nodule had enhancing component with no combined lymphadenopathy on CT scan

  1. Detection is unaffected by the deployment of focal attention

    Directory of Open Access Journals (Sweden)

    Jeff eMoher

    2013-05-01

    Full Text Available There has been much debate regarding how much information humans can extract from their environment without the use of limited attentional resources. In a recent study, Theeuwes, Van der Burg, and Belopolsky (2008 argued that even detection of simple feature targets is not possible without selection by focal attention. Supporting this claim, they found response time benefits in a simple feature (color detection task when a target letter’s identity was repeated on consecutive trials, suggesting that the letter was selected by focal attention and identified prior to detection. This intertrial repetition benefit remained even when observers were required to simultaneously identify a central digit. However, we found that intertrial repetition benefits disappeared when a simple color target was presented among a heterogeneously (rather than homogeneously colored set of distractors, thus reducing its bottom-up salience. Still, detection performance remained high. Thus, detection performance was unaffected by whether a letter was focally attended and identified prior to detection or not. Intertrial identity repetition benefits also disappeared when observers were required to perform a simultaneous, attention-demanding central task (Experiment 2, or when unfamiliar Chinese characters were used (Experiment 3. Together, these results suggest that while shifts of focal attention can be affected by target salience, by the availability of excess cognitive resources, and by target familiarity, detection performance itself is unaffected by these manipulations and is thus unaffected by the deployment of focal attention.

  2. EEG dynamical correlates of focal and diffuse causes of coma.

    Science.gov (United States)

    Kafashan, MohammadMehdi; Ryu, Shoko; Hargis, Mitchell J; Laurido-Soto, Osvaldo; Roberts, Debra E; Thontakudi, Akshay; Eisenman, Lawrence; Kummer, Terrance T; Ching, ShiNung

    2017-11-15

    Rapidly determining the causes of a depressed level of consciousness (DLOC) including coma is a common clinical challenge. Quantitative analysis of the electroencephalogram (EEG) has the potential to improve DLOC assessment by providing readily deployable, temporally detailed characterization of brain activity in such patients. While used commonly for seizure detection, EEG-based assessment of DLOC etiology is less well-established. As a first step towards etiological diagnosis, we sought to distinguish focal and diffuse causes of DLOC through assessment of temporal dynamics within EEG signals. We retrospectively analyzed EEG recordings from 40 patients with DLOC with consensus focal or diffuse culprit pathology. For each recording, we performed a suite of time-series analyses, then used a statistical framework to identify which analyses (features) could be used to distinguish between focal and diffuse cases. Using cross-validation approaches, we identified several spectral and non-spectral EEG features that were significantly different between DLOC patients with focal vs. diffuse etiologies, enabling EEG-based classification with an accuracy of 76%. Our findings suggest that DLOC due to focal vs. diffuse injuries differ along several electrophysiological parameters. These results may form the basis of future classification strategies for DLOC and coma that are more etiologically-specific and therefore therapeutically-relevant.

  3. A targeted resequencing gene panel for focal epilepsy.

    Science.gov (United States)

    Hildebrand, Michael S; Myers, Candace T; Carvill, Gemma L; Regan, Brigid M; Damiano, John A; Mullen, Saul A; Newton, Mark R; Nair, Umesh; Gazina, Elena V; Milligan, Carol J; Reid, Christopher A; Petrou, Steven; Scheffer, Ingrid E; Berkovic, Samuel F; Mefford, Heather C

    2016-04-26

    We report development of a targeted resequencing gene panel for focal epilepsy, the most prevalent phenotypic group of the epilepsies. The targeted resequencing gene panel was designed using molecular inversion probe (MIP) capture technology and sequenced using massively parallel Illumina sequencing. We demonstrated proof of principle that mutations can be detected in 4 previously genotyped focal epilepsy cases. We searched for both germline and somatic mutations in 251 patients with unsolved sporadic or familial focal epilepsy and identified 11 novel or very rare missense variants in 5 different genes: CHRNA4, GRIN2B, KCNT1, PCDH19, and SCN1A. Of these, 2 were predicted to be pathogenic or likely pathogenic, explaining ∼0.8% of the cohort, and 8 were of uncertain significance based on available data. We have developed and validated a targeted resequencing panel for focal epilepsies, the most important clinical class of epilepsies, accounting for about 60% of all cases. Our application of MIP technology is an innovative approach that will be advantageous in the clinical setting because it is highly sensitive, efficient, and cost-effective for screening large patient cohorts. Our findings indicate that mutations in known genes likely explain only a small proportion of focal epilepsy cases. This is not surprising given the established clinical and genetic heterogeneity of these disorders and underscores the importance of further gene discovery studies in this complex syndrome. © 2016 American Academy of Neurology.

  4. Terapia Interpessoal: um modelo breve e focal Interpersonal Therapy: a brief and focal model

    Directory of Open Access Journals (Sweden)

    Marcelo Feijó de Mello

    2004-06-01

    Full Text Available A psicoterapia é uma forma particular de tratamento em psiquiatria. Seu uso é amplamente difundido e conta com várias linhas de abordagem. OBJETIVO: Neste trabalho, o autor faz considerações a respeito da terapia interpessoal (TIP, uma forma breve e focal de psicoterapia. Inicialmente usada para o tratamento da depressão, teve seu espectro de ação ampliado para outros transtornos. A TIP pode ser dividida em 3 fases: inicial, quando é feito um diagnóstico do transtorno nomeando os sintomas ao paciente e diagnosticando o foco interpessoal a ser trabalhado; fase intermediária, onde se trabalha o foco; e fase final, quando o paciente é encorajado a reconhecer e consolidar seus ganhos para usá-los no futuro. MÉTODOS: O autor faz uma revisão das evidências científicas da eficácia da TIP no tratamento da depressão. CONCLUSÕES: Os resultados mostram que a TIP é uma forma terapêutica eficaz e bem tolerada de tratamento para a depressão.Psychotherapy is a particular form of treatment in Psychiatry. Its use is widespread and has many different approaches. OBJECTIVE: In this article, the author makes some considerations about Interpersonal Therapy (IPT, a brief and focal psychotherapy. Initially created to treat depression, other researchers had successfully increase its spectrum. It could be divided in three phases. Initial, when the therapist makes the diagnosis of the disorder and also the interpersonal problematic is pointed out; the patient received a sick role. Intermediary when the focus is treated, and the final phase when the therapist encourages the patient to recognize and consolidate gains and prepare the patient to use it in the future. METHODS: It is stressed that IPT is a testable form of psychotherapy and the scientific evidences of its efficacy are showed. CONCLUSIONS: The results assure that IPT is an efficient form of psychotherapy for depression with a great acceptability from the patients.

  5. Managing Innovation Paradox in the Sustainable Innovation Ecosystem: A Case Study of Ambidextrous Capability in a Focal Firm

    Directory of Open Access Journals (Sweden)

    Delin Zeng

    2017-11-01

    Full Text Available To achieve sustainable development, focal firms should balance two paradoxical kinds of innovation activities: exploitative and exploratory ones. Published works found that ambidexterity is an effective way to resolve paradoxical tensions, but few in-depth studies have been conducted to explore the innovation paradox of focal firms in the innovation ecosystem from an ambidextrous capability perspective. This paper takes China Spacesat Co., Ltd. as the case to study focal firms’ management of innovation paradoxes in the sustainable innovation ecosystem and finds that: (1 Sustainable innovation is an ecosystem in which focal firms’ internal functional departments, including the product department, technical center, and Makers’ groups, cooperate with external organizations, including component suppliers, scientific research institutes, and government departments, closely and complementarily; (2 In the exploitative and exploratory innovations of complex products, focal firms in the sustainable innovation ecosystem mainly confront three paradoxes: profit drive vs. breakthroughs in the strategic intent of sustainable innovation of the profit-driven model, tight vs. loose coupling of sustainable innovation, and sustainable innovation driven by discipline vs. that by passion; (3 Focal firms in the innovation ecosystem resolve these three innovation paradoxes with structural, contextual, and coordinated ambidextrous capabilities, and build innovation paradox management mechanisms with three steps in sequence, namely by establishing dual sustainable strategic innovation units, strengthening sustainable organizational ties between the internal and external, while co-creating and sharing innovation values, and, finally, promoting the formation and development of their sustainable innovation ecosystem. This paper complements and enriches the innovation ecosystem and ambidextrous capability theory, providing significant practical guidance to the

  6. Role of scintigraphy in focally abnormal sonograms of fatty livers

    International Nuclear Information System (INIS)

    Lisbona, R.; Mishkin, S.; Derbekyan, V.; Novales-Diaz, J.A.; Roy, A.; Sanders, L.

    1988-01-01

    Fatty infiltration of the liver may cause a range of focal abnormalities on hepatic sonography which may simulate hepatic nodular lesions. Discrete deposits of fat or islands of normal tissue which are uninvolved by fatty infiltration may stand out as potential space-occupying lesions on the sonograms. Twelve patients with such focally abnormal ultrasound images were referred for liver scintigraphy with 133 Xe and /sup 99m/Tc colloidal SPECT studies to clarify the issue. These examinations helped identify, in nine of 12 patients, the innocent nature of the sonographic abnormalities which were simply related to the fat deposition process. Further, [/sup 99m/Tc]RBC scans defined the additional pathologic process in three patients in whom actual space-occupying lesions were indeed present in the liver. Scintigraphy has an important role to play in the understanding of focal hepatic ultrasound abnormalities particularly in unsuspected hepatic steatosis

  7. Role of scintigraphy in focally abnormal sonograms of fatty livers

    Energy Technology Data Exchange (ETDEWEB)

    Lisbona, R.; Mishkin, S.; Derbekyan, V.; Novales-Diaz, J.A.; Roy, A.; Sanders, L.

    1988-06-01

    Fatty infiltration of the liver may cause a range of focal abnormalities on hepatic sonography which may simulate hepatic nodular lesions. Discrete deposits of fat or islands of normal tissue which are uninvolved by fatty infiltration may stand out as potential space-occupying lesions on the sonograms. Twelve patients with such focally abnormal ultrasound images were referred for liver scintigraphy with /sup 133/Xe and /sup 99m/Tc colloidal SPECT studies to clarify the issue. These examinations helped identify, in nine of 12 patients, the innocent nature of the sonographic abnormalities which were simply related to the fat deposition process. Further, (/sup 99m/Tc)RBC scans defined the additional pathologic process in three patients in whom actual space-occupying lesions were indeed present in the liver. Scintigraphy has an important role to play in the understanding of focal hepatic ultrasound abnormalities particularly in unsuspected hepatic steatosis.

  8. US and CT findings in splenic focal lesions in AIDS

    International Nuclear Information System (INIS)

    Schinina, V.; Rizzi, E.B.; Mazzuoli, G.; Bibbolilno, C.; David, V.

    2000-01-01

    To evaluate the role of US and CT in focal splenic lesions in AIDS patients in relation to etiology. Material and Methods: A total of 66 patients with AIDS and focal splenic lesions were examined with sonography. CT with administration of contrast medium was performed in 12 cases. Results: Of the focal splenic lesions, 67% were correlated with an infective pathology with prevalence of Mycobacteria tuberculosis (75%), 26% were neoplastic and 6% splenic infarcts. The lesions were hypoechoic in 60% of the cases, while 10% were hypoanechoic and 1% anechoic. At CT, all lesions appeared hypodense, even after i.v. administration of contrast medium. Conclusion: The combination of echographic reports and clinical and laboratory data allows for a diagnosis that can be confirmed, and making a decision for effective therapy of AIDS is possible. CT does not provide any additional information

  9. Simulation of the Focal Spot of the Accelerator Bremsstrahlung Radiation

    Science.gov (United States)

    Sorokin, V.; Bespalov, V.

    2016-06-01

    Testing of thick-walled objects by bremsstrahlung radiation (BR) is primarily performed via high-energy quanta. The testing parameters are specified by the focal spot size of the high-energy bremsstrahlung radiation. In determining the focal spot size, the high- energy BR portion cannot be experimentally separated from the low-energy BR to use high- energy quanta only. The patterns of BR focal spot formation have been investigated via statistical modeling of the radiation transfer in the target material. The distributions of BR quanta emitted by the target for different energies and emission angles under normal distribution of the accelerated electrons bombarding the target have been obtained, and the ratio of the distribution parameters has been determined.

  10. MRI of a family with focal abnormalities of gyration

    International Nuclear Information System (INIS)

    Muntaner, L.; Perez-Ferron, J.J.; Herrera, M.; Rosell, J.; Taboada, D.; Climent, S.

    1997-01-01

    Focal abnormalities of gyration (FAG) are developmental disorders that may occur in isolated patients or, as in the case being reported, as part of a familial disorder. Analysis of individuals in a family spanning three generations was carried out using MRI. Abnormalities, present in all members of generations II and III, included focal cortical dysplasia (three patients), focal cortical infolding (two patients) and schizencephaly (one patient); associated minor anomalies, such as white matter abnormalities, were seen in the remaining three members of generations II and III. MRI recognition of FAG in the family being reported proved useful in defining their phenotypical expression and providing proper counselling for individual family members. (orig.). With 6 figs

  11. Protein kinase C involvement in focal adhesion formation

    DEFF Research Database (Denmark)

    Woods, A; Couchman, J R

    1992-01-01

    Matrix molecules such as fibronectin can promote cell attachment, spreading and focal adhesion formation. Although some interactions of fibronectin with cell surface receptors have now been identified, the consequent activation of intracellular messenger systems by cell/matrix interactions have...... still to be elucidated. We show here that the kinase inhibitors H7 and HA1004 reduce focal adhesion and stress fiber formation in response to fibronectin in a dose-dependent manner, and that activators of protein kinase C can promote their formation under conditions where they do not normally form....... Fibroblasts spread within 1h on substrata composed of fibronectin and formed focal adhesions by 3h, as monitored by interference reflection microscopy (IRM) and by labeling for talin, vinculin and integrin beta 1 subunits. In addition, stress fibers were visible. When cells were allowed to spread for 1h...

  12. Focal depth measurement of scanning helium ion microscope

    International Nuclear Information System (INIS)

    Guo, Hongxuan; Itoh, Hiroshi; Wang, Chunmei; Zhang, Han; Fujita, Daisuke

    2014-01-01

    When facing the challenges of critical dimension measurement of complicated nanostructures, such as of the three dimension integrated circuit, characterization of the focal depth of microscopes is important. In this Letter, we developed a method for characterizing the focal depth of a scanning helium ion microscope (HIM) by using an atomic force microscope tip characterizer (ATC). The ATC was tilted in a sample chamber at an angle to the scanning plan. Secondary electron images (SEIs) were obtained at different positions of the ATC. The edge resolution of the SEIs shows the nominal diameters of the helium ion beam at different focal levels. With this method, the nominal shapes of the helium ion beams were obtained with different apertures. Our results show that a small aperture is necessary to get a high spatial resolution and high depth of field images with HIM. This work provides a method for characterizing and improving the performance of HIM.

  13. Mapping and ablating stable sources for atrial fibrillation: summary of the literature on Focal Impulse and Rotor Modulation (FIRM).

    Science.gov (United States)

    Baykaner, Tina; Lalani, Gautam G; Schricker, Amir; Krummen, David E; Narayan, Sanjiv M

    2014-09-01

    Atrial fibrillation (AF) is the most common sustained arrhythmia and the most common indication for catheter ablation. However, despite substantial technical advances in mapping and energy delivery, ablation outcomes remain suboptimal. A major limitation to AF ablation is that the areas targeted for ablation are rarely of proven mechanistic importance, in sharp contrast to other arrhythmias in which ablation targets demonstrated mechanisms in each patient. Focal impulse and rotor modulation (FIRM) is a new approach to demonstrate the mechanisms that sustain AF ("substrates") in each patient that can be used to guide ablation then confirm elimination of each mechanism. FIRM mapping reveals that AF is sustained by 2-3 rotors and focal sources, with a greater number in patients with persistent than paroxysmal AF, lying within spatially reproducible 2.2 ± 1.4-cm(2) areas in diverse locations. This temporospatial reproducibility, now confirmed by several groups using various methods, changes the concepts regarding AF-sustaining mechanisms, enabling localized rather than widespread ablation. Mechanistically, the role of rotors and focal sources in sustaining AF has been demonstrated by the acute and chronic success of source (FIRM) ablation alone. Clinically, adding FIRM to conventional ablation substantially improves arrhythmia freedom compared with conventional ablation alone, and ongoing randomized trials are comparing FIRM-ablation with and without conventional ablation to conventional ablation alone. In conclusion, ablation of patient-specific AF-sustaining mechanisms (substrates), as exemplified by FIRM, may be central to substantially improving AF ablation outcomes.

  14. How to awaken your nanomachines: Site-specific activation of focal adhesion kinases through ligand interactions

    KAUST Repository

    Walkiewicz, Katarzyna Wiktoria

    2015-06-17

    The focal adhesion kinase (FAK) and the related protein-tyrosine kinase 2-beta (Pyk2) are highly versatile multidomain scaffolds central to cell adhesion, migration, and survival. Due to their key role in cancer metastasis, understanding and inhibiting their functions are important for the development of targeted therapy. Because FAK and Pyk2 are involved in many different cellular functions, designing drugs with partial and function-specific inhibitory effects would be desirable. Here, we summarise recent progress in understanding the structural mechanism of how the tug-of-war between intramolecular and intermolecular interactions allows these protein ‘nanomachines’ to become activated in a site-specific manner.

  15. Nodular focal fatty infiltration of the liver: CT appearance

    International Nuclear Information System (INIS)

    Baker, M.E.; Silverman, P.M.

    1985-01-01

    Focal fatty infiltration of the liver is a well recognized entity generally characterized by a nonspherical, low-density area without significant mass effect. CT usually distinguishes this from focal liver processes such as abscess or metastasis by its sharply marginated, geographic pattern and lack of mass effect on hepatic and portal veins. Recently, the authors formed a CT scan of the liver in one patient in whom fatty infiltration appeared nodular or rounded. The clinical presentation and radiographic and pathologic features form the basis of this report

  16. The radiological features of Goltz syndrome: Focal dermal hypoplasia

    International Nuclear Information System (INIS)

    Boothyrod, A.E.; Hall, C.M.

    1988-01-01

    Two female infants with Goltz syndrome (focal dermal hypoplasia) were recently investigated for severe feeding problems and failure to thrive. Both demonstrated severe skeletal malformations and marked gastrooesophageal reflux with laxity of the hiatus. One child (case 1) exhibited nasal regurgitation during feeding. Interestingly, both children had undergone surgery; Case 1 or a right parasagittal abdominal hernia associated with focal dermal hypoplasia of the abdominal wall and Case 2 for an exomphalos also associated with dermal hypoplasia. This observation suggests more widespread mesodermal abnormality. (orig./GDG)

  17. Focal myositis of the thigh: unusual MR pattern

    International Nuclear Information System (INIS)

    Llauger, Jaume; Palmer, Jaume; San Roman, Luis; Bague, Silvia; Matias-Guiu, Xavier; Doncel, Antonio

    2002-01-01

    Focal myositis is a commonly referenced, infrequently reported and poorly documented benign inflammatory pseudotumor which may be misdiagnosed clinically as a malignant tumor. We report the clinicopathologic features and magnetic resonance imaging findings in a case of focal myositis in the thigh of a 55-year-old woman. A different radiologic presentation of this disorder is described. The gross appearance of the lesion, previously undescribed, appears to be rather specific for such a pseudoneoplastic disorder, and correlates very well with the magnetic resonance imaging features. (orig.)

  18. Focal myositis of the thigh: unusual MR pattern

    Energy Technology Data Exchange (ETDEWEB)

    Llauger, Jaume; Palmer, Jaume; San Roman, Luis [Department of Radiology, Hospital de la Santa Creu i Sant Pau, Barcelona (Spain); Bague, Silvia; Matias-Guiu, Xavier [Department of Pathology, Hospital de la Santa Creu i Sant Pau, Barcelona (Spain); Doncel, Antonio [Department of Orthopedic Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona (Spain)

    2002-05-01

    Focal myositis is a commonly referenced, infrequently reported and poorly documented benign inflammatory pseudotumor which may be misdiagnosed clinically as a malignant tumor. We report the clinicopathologic features and magnetic resonance imaging findings in a case of focal myositis in the thigh of a 55-year-old woman. A different radiologic presentation of this disorder is described. The gross appearance of the lesion, previously undescribed, appears to be rather specific for such a pseudoneoplastic disorder, and correlates very well with the magnetic resonance imaging features. (orig.)

  19. Magnetic-resonance-guided biopsy of focal liver lesions

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Ethan A. [University of Michigan Health System, Section of Pediatric Radiology, C.S. Mott Children' s Hospital, Department of Radiology, Ann Arbor, MI (United States); Grove, Jason J. [University of Michigan Health System, Division of Interventional Radiology, C.S. Mott Children' s Hospital, Department of Radiology, Ann Arbor, MI (United States); Der Spek, Abraham F.L.V. [University of Michigan Health System, Department of Anesthesiology, C.S. Mott Children' s Hospital, Ann Arbor, MI (United States); Jarboe, Marcus D. [University of Michigan Health System, Division of Interventional Radiology, C.S. Mott Children' s Hospital, Department of Radiology, Ann Arbor, MI (United States); University of Michigan Health System, Section of Pediatric Surgery, C.S. Mott Children' s Hospital, Department of Surgery, Ann Arbor, MI (United States)

    2017-05-15

    Image-guided biopsy techniques are widely used in clinical practice. Commonly used methods employ either ultrasound (US) or computed tomography (CT) for image guidance. In certain patients, US or CT guidance may be suboptimal, or even impossible, because of artifacts, suboptimal lesion visualization, or both. We recently began performing magnetic resonance (MR)-guided biopsy of focal liver lesions in select pediatric patients with lesions that are not well visualized by US or CT. This report describes our experience performing MR-guided biopsy of focal liver lesions, with case examples to illustrate innovative techniques and novel aspects of these procedures. (orig.)

  20. Magnetic electroanatomical mapping for ablation of focal atrial tachycardias.

    Science.gov (United States)

    Marchlinski, F; Callans, D; Gottlieb, C; Rodriguez, E; Coyne, R; Kleinman, D

    1998-08-01

    Uniform success for ablation of focal atrial tachycardias has been difficult to achieve using standard catheter mapping and ablation techniques. In addition, our understanding of the complex relationship between atrial anatomy, electrophysiology, and surface ECG P wave morphology remains primitive. The magnetic electroanatomical mapping and display system (CARTO) offers an on-line display of electrical activation and/or signal amplitude related to the anatomical location of the recorded sites in the mapped chamber. A window of electrical interest is established based on signals timed from an electrical reference that usually represents a fixed electrogram recording from the coronary sinus or the atrial appendage. This window of electrical interest is established to include atrial activation prior to the onset of the P wave activity associated with the site of origin of a focal atrial tachycardia. Anatomical and electrical landmarks are defined with limited fluoroscopic imaging support and more detailed global chamber and more focal atrial mapping can be performed with minimal fluoroscopic guidance. A three-dimensional color map representing atrial activation or voltage amplitude at the magnetically defined anatomical sites is displayed with on-line data acquisition. This display can be manipulated to facilitate viewing from any angle. Altering the zoom control, triangle fill threshold, clipping plane, or color range can all enhance the display of a more focal area of interest. We documented the feasibility of using this single mapping catheter technique for localizing and ablating focal atrial tachycardias. In a consecutive series of 8 patients with 9 focal atrial tachycardias, the use of the single catheter CARTO mapping system was associated with ablation success in all but one patient who had a left atrial tachycardia localized to the medial aspect of the orifice of the left atrial appendage. Only low power energy delivery was used in this patient because of the

  1. Regional cerebral blood flow in focal cortical epilepsy

    DEFF Research Database (Denmark)

    Hougaard, Kristina Dupont; Oikawa, T; Sveinsdottir, E

    1976-01-01

    Regional cerebral blood flow (rCBF) was studied in ten patients with focal cortical epilepsy. The blood flow was measured by the intra-arterial injection of xenon 133 (133Xe), and the isotope clearance was recorded by a multidetector scintillation camera with 254 detectors. Three patients were....... This finding accords with earlier studies. All nine patients studied in the interictal phase showed, either spontaneously or during activation by intermittent light, focal flow increases in areas presumed to comprise the epileptic focus. These interictal hyperemic foci probably reflect subictal neuronal...

  2. Incidental Detection of Temporary Focal FDG Retention in the Spleen

    Energy Technology Data Exchange (ETDEWEB)

    Park, Youn Joon; Lee, Jai Hyuen; Jee, Keum Nahn; Namgung, Hwan [Dankook Univ. College of Medicine, Seoul (Korea, Republic of)

    2011-06-15

    F 18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is a valuable tool in discriminating malignancy from benign lesion. But because various false positive results reduce the diagnostic specificity, nuclear medicine physicians should be familiar with possible false positive cases. Although many cases of high FDG uptake mimicking malignancy have been reported, temporary intense focal FDG uptake of normal spleen has not been reported previously. We report herein a phenomenon of temporary intense focal FDG uptake of normal spleen without evidence of metastasis in a 46 year old woman with a history of anal cancer.

  3. Expansion characteristics of coronary stents in focal stenoses

    Directory of Open Access Journals (Sweden)

    Schmidt Wolfram

    2017-09-01

    Full Text Available The presented experimental in vitro approach was designed to assess the expansion behavior of stent systems in a resistant focal stenosis model with respect to a potential dog-boning effect. Five different stent systems (nominal diameter 3.0 mm were investigated. The focal stenosis was simulated by a stainless steel tube (ID ≤ 1.20 mm. Stent expansion was performed using a proprietary test device consisting of a test chamber with 37 °C water, 2-axis laser scanner and a pressure controller.

  4. Geodynamics and Stress State of the Earth's Crust in the Greater and Lesser Caucasus (Azerbaijan) collision region

    Science.gov (United States)

    Babayev, Gulam; Akhmedova, Elnare; Babayev, Elvin

    2017-04-01

    The current study researches the present-day stress state of the Earth's crust within the territory of Azerbaijan by using the database of the international research project "World Stress Map" (WSM). The present stress state was also assessed by exploring the effects of the contemporary topographic properties of Caucasus in three-dimensional frame. Aiming to explore the relative roles of regional tectonic conditions in the definition of stress state of Greater and Lesser Caucasus, stress distribution model was developed by the earthquake data (1998-2016) and by the standard techniques of stress field calculation. The results show that the stress orientations are influenced also by the combination of topography and crust thickness distribution even at very large depth. Stress data and earthquake focal mechanisms indicate that the stress state of the Earth's crust of the Greater and Lesser Caucasus is characterized by the compression predominantly oriented across the regional strike. The model results suggest that the Lesser Caucasus and Kur depression are rotating coherently, with little or no internal deformation in a counter-clockwise rotation located near the north-eastern corner of the Black Sea. Orientation of stress axes well consistent with earthquake focal mechanisms revealed that within Upper and Lower Crusts, earthquakes are predominantly thrust-faulting with a number of normal-faulting and some strike-slip faulting. The map of the focal mechanisms and stress distribution suggests that the research area is characterized by the thrust of horizontal compression trending north-north-east in the western part of the southern Caucasus. In the western part of Azerbaijan, the compression takes place between the Main Caucasus Fault and the Kur depression, which strikes south along the northern margin of the mountain range. In addition, a clear transition from the left-lateral strike slip to the predominantly right-lateral strike slip is observed in the southern of

  5. SU-G-206-02: Impact of Focal Spot Sizes On CT Image Quality

    International Nuclear Information System (INIS)

    Bache, S; Rong, J

    2016-01-01

    Purpose: To quantify a radiology team’s assessment of image quality differences between two CT scanner models currently in clinical use, with emphasis on spatial resolution that could be impacted by focal spot size. Methods: Modulation Transfer Functions (MTF) measurements were performed by scanning the impulse source insert module of the Catphan 600 at 120/140 kVp with both large (LFS) and small (SFS) focal spots and reconstructed to 2.5mm and 5.0mm thicknesses on a GE Discovery CT750 HD and a LightSpeed VCT CT scanner. MTFs were calculated by summing the 2D PSF along one-dimension to obtain line-spread-function (LSF), and calculating the Fourier Transform of the zero-padded and background corrected LSF. Spatial resolution performance was evaluated by comparing MTF curves, 50% and 10% MTF cutoff, and total area under the MTF curve (AUC). In addition, images of the Catphan high-contrast module and a Kagaku anthropomorphic body phantom were acquired from the HD scanner for visual comparisons. Results: For each scanner model, SFS was superior to LFS spatial resolution with respect to 50%/10% MTF cutoff and AUC. For the HD, 50%/10% cutoff was 4.29/7.22cm-1 for the LFS and 4.43/7.45cm-1 for the SFS. VCT outperformed HD, with 50%/10% cutoff of 4.40/7.29 cm-1 for LFS and 4.62/7.47cm-1 for SFS. Scanner model performance in order of decreasing AUC performance was VCT SFS (7.43), HD SFS (7.20), VCT LFS (7.09) and HD LFS (6.93). Visual evaluations of Kagaku phantom images confirmed that VCT outperformed HD. Conclusion: VCT outperformed HD and small focal spot is desired for either model over large focal spot in term of spatial resolution – in agreement with radiologist feedback of overall image quality. In-depth evaluations of clinical impact and focal spot selection mechanisms is currently being assessed.

  6. Focal symmetrical encephalomalacia in sheep Encefalomalacia focal simétrica em ovino

    Directory of Open Access Journals (Sweden)

    Luciano A. Pimentel

    2010-05-01

    Full Text Available Focal symmetrical encephalomalacia (FSE is the most prominent lesion seen in the chronic form of enterotoxemia by Clostridium perfringens type D. This paper reports FSE in sheep in Brazil. Six deaths occurred within a seven days period in a flock of 70, four to 30-month-old Santa Inês sheep in the state of Paraíba in the Brazilian semiarid. The flock was grazing a paddock of irrigated sprouting Cynodon dactylon (Tifton grass, and supplemented, ad libitum, with a concentrate of soybean, corn and wheat. Nervous signs included blindness and recumbence. A 19 month-old sheep was examined clinically and necropsied after a clinical course of three days. Gross lesions were herniation of the cerebellar vermis and multifocal, bilateral, symmetric brownish areas in the internal capsule, thalamus and cerebellar peduncles. Histologic lesions were multifocal, bilateral malacia with some neutrophils, swelling of blood vessels endothelium, perivascular edema, and hemorrhages. The flock was vaccinated, before the outbreak, with only one dose of Clostridium perfringens type D vaccine. Two factors are suggested to be important for the occurrence of the disease: insufficient immunity due to the incorrect vaccination; and high nutritional levels by the supplementation with highly fermentable carbohydrates.Encefalomalacia focal simétrica (EFS é a lesão mais proeminente vista nas formas subaguda ou crônica da enterotoxemia por Clostridium perfringens tipo D. Este trabalho relata EFS em ovinos no semiárido do estado da Paraíba. Seis ovinos morreram, em um período de sete dias, dentro de um rebanho de 70 animais, da raça Santa Inês, entre 4-30 meses de idade, que pastavam em piquete de Cynodon dactylon (capim Tifton, que estava rebrotando. Os ovinos eram suplementados com um concentrado de soja, trigo e milho. Os sinais nervosos incluíam cegueira e decúbito lateral. Um ovino de 19 meses de idade foi examinado clinicamente e necropsiado, depois de um curso

  7. Idiopathic focal segmental glomerulosclerosis: a favourable prognosis in untreated patients?

    NARCIS (Netherlands)

    Deegens, J.K.J.; Assmann, K.J.M.; Steenbergen, E.; Hilbrands, L.B.; Gerlag, P.G.G.; Jansen, J.L.; Wetzels, J.F.M.

    2005-01-01

    BACKGROUND: Patients with focal segmental glomerulosclerosis (FSGS) are considered to have a poor prognosis and spontaneous remissions are seldom reported. However, FSGS is not a single disease entity. Our aim was to describe the clinical course in initially untreated patients with recently

  8. Laser Beam Caustic Measurement with Focal Spot Analyser

    DEFF Research Database (Denmark)

    Olsen, Flemming Ove; Gong, Hui; Bagger, Claus

    2005-01-01

    In industrial applications of high power CO2-lasers the caustic characteristics of the laser beam have great effects on the performance of the lasers. A welldefined high intense focused spot is essential for reliable production results. This paper presents a focal spot analyser that is developed...

  9. A 1.3 giga pixels focal plane for GAIA

    Science.gov (United States)

    Laborie, Anouk; Pouny, Pierre; Vetel, Cyril; Collados, Emmanuel; Rougier, Gilles; Davancens, Robert; Zayer, Igor; Perryman, Michael; Pace, Oscar

    2004-06-01

    The astrometric mission GAIA is a cornerstone mission of the European Space Agency, due for launch in the 2010 time frame. Requiring extremely demanding performance GAIA calls for the development of an unprecedented large focal plane featuring innovative technologies. For securing the very challenging GAIA development, a significant number of technology activities have been initiated by ESA through a competitive selection process. In this context, an industrial consortium led by EADS-Astrium (France) with e2v technologies (UK) as major subcontractor was selected for the GAIA CCD and Focal Plane Technology Demonstrators programme, which is by far the most significant and the most critical GAIA pre-development for all aspects: science performance, development schedule and cost. This programme has started since August 2002 and will end early 2005 prior to commencement of the GAIA Phase B. While the GAIA payload will host three instruments and related focal planes, the major mission objectives are assigned to the Astrometric (ASTRO) Focal Plane, which is the subject of this presentation.

  10. A case of pathological rib fractures: focal osteolysis or osteoporosis?

    Science.gov (United States)

    Vrbanić, T S L; Novak, S; Sestan, B; Tudor, A; Gulan, G

    2008-03-01

    This paper reports on a unique, previously unreported, successful outcome in the case of a patient with focal osteolytic lesions of the ribs as a first sign of osteoporosis. The lesions were detected by chance after acute cough-induced rib fractures were seen on plain chest radiographs. The diagnosis had to be approached as a diagnosis of exclusion since known causes of the osteolytic process had to be eliminated. The authors describe multiple focal osteolytic lesions with rib fractures appearing in a pattern that could be confused with metastases. Laboratory results were normal. Final diagnosis was based on plain radiography, bone scan and bone densitometry. Pharmacomedical treatments for osteoporosis were applied. The patient was observed between the year 2000 and 2005. Five years later radiological and bone scintigraphy revealed resolution of the lesion. We conclude that osteoporosis should be included in the differential diagnosis of asymptomatic focal osteolysis of the ribs with rib fractures as a complication of acute cough. The case suggests that focal osteolytic lesions of the ribs may regress over time and become scintigraphically inactive.

  11. Shared Focal Plane Investigation for Serial Frame Cameras.

    Science.gov (United States)

    1980-03-01

    capability will be restored. 41. -.. TrABLE 1-1 SYSTEM LEADING P) ARTICULARS Lens Focal Length (inches) Range (ft) Contrast 12 18 24 Coverage 22.1...can be expected that signature bands will be apparent in the imagery. Such bands are at best distracting and at worst hindrances to image interpretation

  12. Tratamento focal e perifocal contra Aëdes aegypti

    Directory of Open Access Journals (Sweden)

    Milton Moura Lima

    1987-06-01

    Full Text Available Em quatro bairros da cidade do Rio de Janeiro, foram feitos ensaios de tratamento focal com abate granulado a 1 ppm e perifocal com pó molhável de Sumition a 2,5%. Esses tratamentos foram feitos tanto isoladamente quanto em conjunto e, também, associados à aplicação de inseticida a ultrabaixo volume. Os índices prediais, levantados um mês depois de terminado o trabalho, mostraram que o tratamento focal dispensa qualquer medida auxiliar. O tratamento perifocal mostrou-se inócuo e incapaz de impedir o aparecimento de larvas de Aëdes aegypti e de outros insetos, em pneus pintados, na face externa, com Sumition e com Malation.In four districts of the city of Rio dc Janeiro focal treatment essays with granulated Abate at 1 ppm and perifocal treatment essays with wettable powder of Sumithion at 2,5% were performed. These were made either alone or in combination as well as associated to insecticides applied at ultra low volume. The premise indices obtained one month after the treatments indicates that the focal treatment alone is effective, no other addicional methods being necessary. The perifocal treatment is not effective and did not prevent the development of Aedes aegypti larvae and other insects in tires which had their external surface painted with Sumithion and Malathion.

  13. Neurophysiological evidence for cerebellar dysfunction in primary focal dystonia.

    NARCIS (Netherlands)

    Teo, J.T.; Warrenburg, B.P.C. van de; Schneider, S.A.; Rothwell, J.C.; Bhatia, K.P.

    2009-01-01

    Recent studies have suggested that there may be functional and structural changes in the cerebellum of patients with adult onset primary focal dystonia. The aim of this study was to establish whether there is any neurophysiological indicator of abnormal cerebellar function, using the classic

  14. The Localizing Value Of Focal Delta Slowing In Temporal Lobe ...

    African Journals Online (AJOL)

    Slow wave EEG had a higher marginal probability than neuropsychological assessment of predicting the focus, and was equally effective as other investigative methods. Conclusion These results suggest that focal temporal delta slowing is useful in the localization of epileptogenic foci. There was no discordance with the ...

  15. Management of HIV-associated focal brain lesions in developing ...

    African Journals Online (AJOL)

    Background. HIV-associated focal brain lesions (FBLs) are caused by opportunistic infections, neoplasms, or cerebrovascular diseases. In developed countries toxoplasma encephalitis (TE) is the most frequent cause followed by primary CNS lymphoma (PCNSL). Guidelines based on these causes have been proposed ...

  16. Quantum-Well Infrared Photodetector (QWIP) Focal Plane Assembly

    Science.gov (United States)

    Jhabvala, Murzy; Jhabvala, Christine A.; Ewin, Audrey J.; Hess, Larry A.; Hartmann, Thomas M.; La, Anh T.

    2012-01-01

    A paper describes the Thermal Infrared Sensor (TIRS), a QWIP-based instrument intended to supplement the Operational Land Imager (OLI) for the Landsat Data Continuity Mission (LDCM). The TIRS instrument is a far-infrared imager operating in the pushbroom mode with two IR channels: 10.8 and 12 microns. The focal plane will contain three 640x512 QWIP arrays mounted on a silicon substrate. The silicon substrate is a custom-fabricated carrier board with a single layer of aluminum interconnects. The general fabrication process starts with a 4-in. (approx.10-cm) diameter silicon wafer. The wafer is oxidized, a single substrate contact is etched, and aluminum is deposited, patterned, and alloyed. This technology development is aimed at incorporating three large-format infrared detecting arrays based on GaAs QWIP technology onto a common focal plane with precision alignment of all three arrays. This focal plane must survive the rigors of flight qualification and operate at a temperature of 43 K (-230 C) for five years while orbiting the Earth. The challenges presented include ensuring thermal compatibility among all the components, designing and building a compact, somewhat modular system and ensuring alignment to very tight levels. The multi-array focal plane integrated onto a single silicon substrate is a new application of both QWIP array development and silicon wafer scale integration. The Invar-based assembly has been tested to ensure thermal reliability.

  17. [Primary focal dystonia: descriptive study of 205 patients].

    Science.gov (United States)

    Bartolomé, F M; Fanjul, S; Cantarero, S; Hernández, J; García Ruiz, P J

    2003-03-01

    To describe the clinical and epidemiologic aspects of different types of focal dystonia. A total of 205 patients with primary focal dystonia were studied retrospectively and the following variables were analyzed: gender, age of onset, age at examination, evolution time, history of trauma, association with other movement disorders, fluctuations of dystonic symptoms as well as a family history of dystonia, Parkinson's disease, tremor, and lefthandedness or stuttering. We compared these variables among the different clinical categories of focal dystonia. Those patients with cranial and laryngeal dystonia were significantly older at the onset of symptoms compared with patients with writer's cramp. Males were more prevalent than females in all categories of focal dystonia except for cranial dystonia. Prior history of trauma and association with tremor were more frequent in patients with cervical dystonia than in those with others dystonic categories. Most patients with cranial, cervical and laryngeal dystonia had fluctuations in the intensity of dystonic symptoms, unlike the patients with writer's cramp. There is a caudo-cranial gradient in age of onset and the age of onset increases as the cranial presentation becomes greater. Females are more prevalent in cranial dystonia and there is a preponderance of males in the dystonias with a lower location. The dystonias with cranial distribution frequently present fluctuations of symptoms during the day. Association with other movement disorders, such as tremor, and prior history of trauma, is common in patients with cervical dystonia.

  18. Focal fibrocartilaginous dysplasia and tibia vara: a case report

    International Nuclear Information System (INIS)

    Cockshott, W.P.; Martin, R.; Friedman, L.; Yuen, M.

    1994-01-01

    A 2-year-old black boy with focal fibrocartilaginous dysplasia is described with illustrations of the typical radiographic appearances supplemented by computed tomographic and magnetic resonance images. Since this rare condition is self-correcting, diagnosis is important so that surgical intervention and biopsy can be avoided and conservative management instituted. (orig.)

  19. Focal fibrocartilaginous dysplasia and tibia vara: a case report.

    Science.gov (United States)

    Cockshott, W P; Martin, R; Friedman, L; Yuen, M

    1994-07-01

    A 2-year-old black boy with focal fibrocartilaginous dysplasia is described with illustrations of the typical radiographic appearances supplemented by computed tomographic and magnetic resonance images. Since this rare condition is self-correcting, diagnosis is important so that surgical intervention and biopsy can be avoided and conservative management instituted.

  20. Focal fibrocartilaginous dysplasia and tibia vara: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Cockshott, W.P. (Dept. of Radiology, McMaster Univ. Medical Centre, Hamilton, ON (Canada)); Martin, R. (Dept. of Orthopedics, McMaster Univ. Medical Centre, Hamilton, ON (Canada)); Friedman, L. (Dept. of Radiology, McMaster Univ. Medical Centre, Hamilton, ON (Canada)); Yuen, M. (Dept. of Radiology, McMaster Univ. Medical Centre, Hamilton, ON (Canada))

    1994-07-01

    A 2-year-old black boy with focal fibrocartilaginous dysplasia is described with illustrations of the typical radiographic appearances supplemented by computed tomographic and magnetic resonance images. Since this rare condition is self-correcting, diagnosis is important so that surgical intervention and biopsy can be avoided and conservative management instituted. (orig.)

  1. Contrast enhanced ultrasound in CT-undetermined focal liver lesions

    DEFF Research Database (Denmark)

    Sandrose, Sebastian; Karstrup, S.; Gerke, Oke

    2016-01-01

    , surgical resection, PET/CT and clinical follow-up. Results: The 78 included patients had 163 undetermined focal liver lesions, mean size 1.1 cm, range 0.1–5.3 cm. There were 18 malignant and 145 benign liver lesions, as defined by the standard of reference. In differentiating between benign vs. malignant...

  2. Automatic test comes to focal plane array production

    Science.gov (United States)

    Skaggs, Frank L.; Barton, T. D.

    1992-08-01

    To meet the needs of military and commercial markets, the infrared focal plane array industry must develop new, effective and low cost methods of fabricating and testing imaging detectors. This paper describes Texas Instruments new concepts in automated testing and cold probe technology as they apply to volume production.

  3. Focal irreversible electroporation as primary treatment for localized prostate cancer

    NARCIS (Netherlands)

    van den Bos, Willemien; Scheltema, Matthijs J.; Siriwardana, Amila R.; Kalsbeek, Anton M. F.; Thompson, James E.; Ting, Francis; Böhm, Maret; Haynes, Anne-Maree; Shnier, Ron; Delprado, Warick; Stricker, Phillip D.

    2017-01-01

    To determine the safety, quality of life (QoL) and short-term oncological outcomes of primary focal IRE for the treatment of localized prostate cancer. To identify potential risk factors for oncological failure. Patients that met both the consensus guidelines on patient criteria and selection

  4. Position sensitive proportional counters as focal plane detectors

    International Nuclear Information System (INIS)

    Ford, J.L.C. Jr.

    1979-01-01

    The rise time and charge division techniques for position decoding with RC-line proportional counters are reviewed. The advantages that these detectors offer as focal plane counters for nuclear spectroscopy performed with magnetic spectrographs are discussed. The theory of operation of proportional counters as position sensing devices is summarized, as well as practical aspects affecting their application. Factors limiting the position and energy resolutions obtainable with a focal plane proportional counter are evaluated and measured position and energy loss values are presented for comparison. Detector systems capable of the multiparameter measurements required for particle identification, background suppression and ray-tracing are described in order to illustrate the wide applicability of proportional counters within complex focal plane systems. Examples of the use of these counters other than with magnetic spectrographs are given in order to demonstrate their usefulness in not only nuclear physics but also in fields such as solid state physics, biology, and medicine. The influence of the new focal plane detector systems on future magnetic spectrograph designs is discussed. (Auth.)

  5. White matter integrity and cerebral network topology in focal epilepsy

    NARCIS (Netherlands)

    Otte, W.M.

    2012-01-01

    Worldwide more than fifty million people suffer from recurrent spontaneous seizures. Seizures are considered to be harmful to the brain and may have adverse long-term behavioral and cognitive consequences in particular in people with focal epilepsies that do not respond to pharmacotherapy.

  6. Mutations in KCNT1 cause a spectrum of focal epilepsies

    Science.gov (United States)

    Møller, Rikke S.; Heron, Sarah E.; Larsen, Line H. G.; Lim, Chiao Xin; Ricos, Michael G.; Bayly, Marta A.; van Kempen, Marjan J. A.; Klinkenberg, Sylvia; Andrews, Ian; Kelley, Kent; Ronen, Gabriel M.; Callen, David; McMahon, Jacinta M.; Yendle, Simone C.; Carvill, Gemma L.; Mefford, Heather C.; Nabbout, Rima; Poduri, Annapurna; Striano, Pasquale; Baglietto, Maria G.; Zara, Federico; Smith, Nicholas J.; Pridmore, Clair; Gardella, Elena; Nikanorova, Marina; Dahl, Hans Atli; Gellert, Pia; Scheffer, Ingrid E.; Gunning, Boudewijn; Kragh-Olsen, Bente; Dibbens, Leanne M.

    2018-01-01

    Summary Autosomal dominant mutations in the sodium-gated potassium channel subunit gene KCNT1 have been associated with two distinct seizure syndromes, nocturnal frontal lobe epilepsy (NFLE) and malignant migrating focal seizures of infancy (MMFSI). To further explore the phenotypic spectrum associated with KCNT1, we examined individuals affected with focal epilepsy or an epileptic encephalopathy for mutations in the gene. We identified KCNT1 mutations in 12 previously unreported patients with focal epilepsy, multifocal epilepsy, cardiac arrhythmia, and in a family with sudden unexpected death in epilepsy (SUDEP), in addition to patients with NFLE and MMFSI. In contrast to the 100% penetrance so far reported for KCNT1 mutations, we observed incomplete penetrance. It is notable that we report that the one KCNT1 mutation, p.Arg398Gln, can lead to either of the two distinct phenotypes, ADNFLE or MMFSI, even within the same family. This indicates that genotype–phenotype relationships for KCNT1 mutations are not straightforward. We demonstrate that KCNT1 mutations are highly pleiotropic and are associated with phenotypes other than ADNFLE and MMFSI. KCNT1 mutations are now associated with Ohtahara syndrome, MMFSI, and nocturnal focal epilepsy. They may also be associated with multifocal epilepsy and cardiac disturbances. PMID:26122718

  7. Differential diagnosis of focal pancreatitis and pancreatic cancer

    NARCIS (Netherlands)

    van Gulik, T. M.; Moojen, T. M.; van Geenen, R.; Rauws, E. A.; Obertop, H.; Gouma, D. J.

    1999-01-01

    The differentiation of focal, chronic pancreatitis (CP) and pancreatic cancer (PAC) poses a diagnostic dilemma. Both conditions may present with the same symptoms and signs. The complexity of differential diagnosis is enhanced because PAC is frequently associated with secondary inflammatory changes

  8. Mutations in KCNT1 cause a spectrum of focal epilepsies

    DEFF Research Database (Denmark)

    Møller, Rikke Steensbjerre; Heron, Sarah E.; Larsen, Line H. G.

    2015-01-01

    Autosomal dominant mutations in the sodium-gated potassium channel subunit gene KCNT1 have been associated with two distinct seizure syndromes, nocturnal frontal lobe epilepsy (NFLE) and malignant migrating focal seizures of infancy (MMFSI). To further explore the phenotypic spectrum associated w...

  9. Dosimetry Modeling for Focal Low-Dose-Rate Prostate Brachytherapy

    Energy Technology Data Exchange (ETDEWEB)

    Al-Qaisieh, Bashar [Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds (United Kingdom); Mason, Josh, E-mail: joshua.mason@nhs.net [Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds (United Kingdom); Bownes, Peter; Henry, Ann [Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds (United Kingdom); Dickinson, Louise [Division of Surgery and Interventional Science, University College London, London (United Kingdom); Department of Radiology, Northwick Park Hospital, London North West NHS Trust, London (United Kingdom); Ahmed, Hashim U. [Division of Surgery and Interventional Science, University College London, London (United Kingdom); University College London Hospital, London (United Kingdom); Emberton, Mark [University College London Hospital, London (United Kingdom); Langley, Stephen [St Luke' s Cancer Centre, Guildford (United Kingdom)

    2015-07-15

    Purpose: Focal brachytherapy targeted to an individual lesion(s) within the prostate may reduce side effects experienced with whole-gland brachytherapy. The outcomes of a consensus meeting on focal prostate brachytherapy were used to investigate optimal dosimetry of focal low-dose-rate (LDR) prostate brachytherapy targeted using multiparametric magnetic resonance imaging (mp-MRI) and transperineal template prostate mapping (TPM) biopsy, including the effects of random and systematic seed displacements and interseed attenuation (ISA). Methods and Materials: Nine patients were selected according to clinical characteristics and concordance of TPM and mp-MRI. Retrospectively, 3 treatment plans were analyzed for each case: whole-gland (WG), hemi-gland (hemi), and ultra-focal (UF) plans, with 145-Gy prescription dose and identical dose constraints for each plan. Plan robustness to seed displacement and ISA were assessed using Monte Carlo simulations. Results: WG plans used a mean 28 needles and 81 seeds, hemi plans used 17 needles and 56 seeds, and UF plans used 12 needles and 25 seeds. Mean D90 (minimum dose received by 90% of the target) and V100 (percentage of the target that receives 100% dose) values were 181.3 Gy and 99.8% for the prostate in WG plans, 195.7 Gy and 97.8% for the hemi-prostate in hemi plans, and 218.3 Gy and 99.8% for the focal target in UF plans. Mean urethra D10 was 205.9 Gy, 191.4 Gy, and 92.4 Gy in WG, hemi, and UF plans, respectively. Mean rectum D2 cm{sup 3} was 107.5 Gy, 77.0 Gy, and 42.7 Gy in WG, hemi, and UF plans, respectively. Focal plans were more sensitive to seed displacement errors: random shifts with a standard deviation of 4 mm reduced mean target D90 by 14.0%, 20.5%, and 32.0% for WG, hemi, and UF plans, respectively. ISA has a similar impact on dose-volume histogram parameters for all plan types. Conclusions: Treatment planning for focal LDR brachytherapy is feasible. Dose constraints are easily met with a notable

  10. HAb18G/CD147 regulates vinculin-mediated focal adhesion and cytoskeleton organization in cultured human hepatocellular carcinoma cells.

    Directory of Open Access Journals (Sweden)

    Qiang Liang

    Full Text Available Focal adhesions (FAs, integrin-mediated macromolecular complexes located at the cell membrane extracellular interface, have been shown to regulate cell adhesion and migration. Our previous studies have indicated that HAb18G/CD147 (CD147 is involved in cytoskeleton reorganization and FA formation in human hepatocellular carcinoma (HCC cells. However, the precise mechanisms underlying these processes remain unclear. In the current study, we determined that CD147 was involved in vinculin-mediated FA focal adhesion formation in HCC cells. We also found that deletion of CD147 led to reduced vinculin-mediated FA areas (P<0.0001, length/width ratios (P<0.0001, and mean intensities (P<0.0001. CD147 promoted lamellipodia formation by localizing Arp2/3 to the leading edge of the cell. Deletion of CD147 significantly reduced the fluorescence (t1/2 recovery times (22.7±3.3 s of vinculin-mediated focal adhesions (P<0.0001. In cell-spreading assays, CD147 was found to be essential for dynamic focal adhesion enlargement and disassembly. Furthermore, the current data showed that CD147 reduced tyrosine phosphorylation in vinculin-mediated focal adhesions, and enhanced the accumulation of the acidic phospholipid phosphatidylinositol-4, 5-bisphosphate (PIP2. Together, these results revealed that CD147 is involved in vinculin-mediated focal adhesion formation, which subsequently promotes cytoskeleton reorganization to facilitate invasion and migration of human HCC cells.

  11. Context cue focality influences strategic prospective memory monitoring.

    Science.gov (United States)

    Hunter Ball, B; Bugg, Julie M

    2018-02-12

    Monitoring the environment for the occurrence of prospective memory (PM) targets is a resource-demanding process that produces cost (e.g., slower responding) to ongoing activities. However, research suggests that individuals are able to monitor strategically by using contextual cues to reduce monitoring in contexts in which PM targets are not expected to occur. In the current study, we investigated the processes supporting context identification (i.e., determining whether or not the context is appropriate for monitoring) by testing the context cue focality hypothesis. This hypothesis predicts that the ability to monitor strategically depends on whether the ongoing task orients attention to the contextual cues that are available to guide monitoring. In Experiment 1, participants performed an ongoing lexical decision task and were told that PM targets (TOR syllable) would only occur in word trials (focal context cue condition) or in items starting with consonants (nonfocal context cue condition). In Experiment 2, participants performed an ongoing first letter judgment (consonant/vowel) task and were told that PM targets would only occur in items starting with consonants (focal context cue condition) or in word trials (nonfocal context cue condition). Consistent with the context cue focality hypothesis, strategic monitoring was only observed during focal context cue conditions in which the type of ongoing task processing automatically oriented attention to the relevant features of the contextual cue. These findings suggest that strategic monitoring is dependent on limited-capacity processing resources and may be relatively limited when the attentional demands of context identification are sufficiently high.

  12. Standards and pitfalls of focal ischemia models in spontaneously hypertensive rats: With a systematic review of recent articles

    Directory of Open Access Journals (Sweden)

    Yao Hiroshi

    2012-07-01

    Full Text Available Abstract We reviewed the early development of various focal ischemia models in spontaneously hypertensive rats (SHR, and summarized recent reports on this topic. Among 6 focal ischemia models established in divergent substrains of SHR, distal middle cerebral artery occlusion is the most frequently used and relevant method of focal ischemia in the light of penumbra concept. We performed an online PubMed search (2001–2010, and identified 118 original articles with focal ischemia in SHR. Physiological parameters such as age, body weight, and even blood pressure were often neglected in the literature: the information regarding the physiological parameters of SHR is critical, and should be provided within the methodology section of all articles related to stroke models in SHR. Although the quality of recent studies on neuroprotective strategy is improving, the mechanisms underlying the protection should be more clearly recognized so as to facilitate the translation from animal studies to human stroke. To overcome the genetic heterogeneity in substrains of SHR, new approaches, such as a huge repository of genetic markers in rat strains and the congenic strategy, are currently in progress.

  13. Microstructural and seismic properties of the upper mantle underneath a rifted continental terrane (Baja California): An example of sub-crustal mechanical asthenosphere?

    NARCIS (Netherlands)

    Palasse, L.N.; Vissers, R.L.M.; Paulssen, H.; Basu, A.R.; Drury, M.R.

    2012-01-01

    The Gulf of California rift is a young and active plate boundary that links the San Andreas strike-slip fault system in California to the oceanic spreading system of the East Pacific Rise. The xenolith bearing lavas of the San Quintin volcanic area provide lower crust and upper mantle samples from

  14. Seismic evidence of conjugate normal faulting: The 1994 Devil Canyon earthquake sequence near Challis, Idaho

    International Nuclear Information System (INIS)

    Jackson, S.M.

    1994-08-01

    In this study, the term ''conjugate'' refers to faults that occur in two intersecting sets and coordinated kinematically, with each set being distinctive in both orientation and sense of shear (Davis, 1984). Contemporaneous activity along the conjugate faults is defined as occurring within the time frame of the mainshock-aftershock sequence (three weeks for this sequence and generally less than one month in other observed cases). Detailed recordings of microearthquakes from a dense array of temporary analog seismic stations are analyzed. The focal mechanisms and hypocenter spatial and temporal characteristics are combined with geological information to assess the style, geometry, timing, kinematics, and mechanics of conjugate normal faulting. The characteristics of conjugate normal faulting observed in the Devil Canyon sequence are compared to other conjugate normal faulting sequences, and strike-slip and thrust conjugate sequences worldwide

  15. Sulforaphane exerts neuroprotective effects via suppression of the inflammatory response in a rat model of focal cerebral ischemia

    OpenAIRE

    Ma, Li-Li; Xing, Guo-Ping; Yu, Yin; Liang, Hui; Yu, Tian-Xia; Zheng, Wei-Hong; Lai, Tian-Bao

    2015-01-01

    Inflammatory damage plays an important role in cerebral ischemic pathogenesis and may represent a promising target for treatment. Sulforaphane exerts protective effects in a rat model of focal cerebral ischemia/reperfusion injury by alleviating brain edema. However, the possible mechanisms of sulforaphane after cerebral ischemia/reperfusion injury have not been fully elucidated. Therefore, in the present study, we investigated the effect of sulforaphane on inflammatory reaction and the potent...

  16. The flexible engagement of monitoring processes in non-focal and focal prospective memory tasks with salient cues.

    Science.gov (United States)

    Hefer, Carmen; Cohen, Anna-Lisa; Jaudas, Alexander; Dreisbach, Gesine

    2017-09-01

    Prospective memory (PM) refers to the ability to remember to perform a delayed intention. Here, we aimed to investigate the ability to suspend such an intention and thus to confirm previous findings (Cohen, Gordon, Jaudas, Hefer, & Dreisbach, 2016) demonstrating the ability to flexibly engage in monitoring processes. In the current study, we presented a perceptually salient PM cue (bold and red) to rule out that previous findings were limited to non-salient and, thus, easy to ignore PM cues. Moreover, we used both a non-focal (Experiment 1) and a focal PM (Experiment 2) cue. In both Experiments, three groups of participants performed an Eriksen flanker task as an ongoing task with an embedded PM task (they had to remember to press the F1 key if a pre-specified cue appeared). Participants were assigned to either a control condition (performed solely the flanker task), a standard PM condition (performed the flanker task along with the PM task), or a PM delayed condition (performed the flanker task but were instructed to postpone their PM task intention). The results of Experiment 1 with the non-focal PM cue closely replicated those of Cohen et al. (2016) and confirmed that participants were able to successfully postpone the PM cue intention without additional costs even when the PM cue was a perceptually salient one. However, when the PM cue was focal (Experiment 2), it was much more difficult for participants to ignore it as evidenced by commission errors and slower latencies on PM cue trials. In sum, results showed that the focality of the PM cue plays a more crucial role in the flexibility of the monitoring process whereas the saliency of the PM cue does not. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Thermography Examination of Abdominal Area Skin Temperatures in Individuals With and Without Focal-Onset Epilepsy.

    Science.gov (United States)

    King, Hollis H; Cayce, Charles Thomas; Herrin, Jeph

    Early osteopathic theory and practice, and the work of the medical intuitive Edgar Cayce suggested that the abdominal areas of individuals with epilepsy would manifest "cold spots." The etiology for this phenomenon was thought to be abdominal adhesions caused by inflammation and viscero-somatic reflexes caused by adhesions or injury to visceral or musculoskeletal system structures. Indeed, until that advent of electroencephalography in the 1930s, medical practice regarding epilepsy focused on abdominal neural and visceral structures. Following two hypotheses were formulated to evaluate any abdominal temperature phenomena: (1) an abdominal quadrant division analysis would find one or more quadrants "colder" in the focal-onset epilepsy group (ICD9-CM 345.4 and 345.5) compared to controls. (2) Total abdominal areas of individuals with focal-onset epilepsy wound be colder than a control group. Overall, 50 patients with the diagnosis of focal-onset epilepsy were recruited from the office of the Epilepsy Foundation of Florida and 50 control subjects with no history of epilepsy were recruited through advertising to the public. Under controlled room conditions all subjects had infrared thermographic images made and recorded by Med-Hot Model MH-731 FLIR equipment. There were no significant demographic difference between experimental patients and control subjects, though the control group tended to be younger and more often male; however, these were controlled for in all analyses. In the quadrant analysis, there were significant differences in that more epileptic patients had colder left upper abdominal quadrant temperatures than the control group (66.8% versus 44.9%; P = .030). In the total abdominal analysis, however, there were no significant differences. The results support the hypothesis that individuals with focal-onset epilepsy have colder abdominal areas. If substantiated in further research, present study results will require further examination of the mechanisms of

  18. Natural-focal diseases: mapping experience in Russia.

    Science.gov (United States)

    Malkhazova, Svetlana M; Mironova, Varvara A; Kotova, Tatiana V; Shartova, Natalia V; Orlov, Dmitry S

    2014-06-14

    Natural-focal diseases constitute a serious hazard for human health. Agents and vectors of such diseases belong to natural landscapes. The aim of this study is to identify the diversity and geography of natural-focal diseases in Russia and to develop cartographic approaches for their mapping, including mathematical-cartographical modeling. Russian medico-geographical mapping of natural-focal diseases is highly developed regionally and locally but extremely limited at the national level. To solve this problem, a scientific team of the Faculty of Geography at Lomonosov Moscow State University has developed and implemented a project of a medico-geographical Atlas of Russia "Natural-Focal Diseases". The mapping is based on medical statistics data. The Atlas contains a series of maps on disease incidence, long-term dynamics of disease morbidity, etc. In addition, other materials available to the authors were used: mapping of the natural environment, field data, archival materials, analyzed satellite images, etc. The maps are processed using ArcGIS (ESRI) software application. Different methods of rendering of mapped phenomena are used (geographical ranges, diagrams, choropleth maps etc.). A series of analytical, integrated, and synthetic maps shows disease incidence in the population at both the national and regional levels for the last 15 years. Maps of the mean annual morbidity of certain infections and maps of morbidity dynamics and nosological profiles allow for a detailed analysis of the situation for each of 83 administrative units of the Russian Federation. The degree of epidemic hazard in Russia by natural-focal diseases is reflected in a synthetic medico-geographical map that shows the degree of epidemic risks due to such diseases in Russia and allows one to estimate the risk of disease manifestation in a given region. This is the first attempt at aggregation and public presentation of diverse and multifaceted information about natural-focal diseases in Russia

  19. CT and ERCP findings of chronic focal pancreatitis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hee Soo; Lee, Jong Tae; Yoo, Hyung Sik; Kim, Eun Kyeong [Yonsei Univ. College of Medicine, Seoul (Korea, Republic of)

    1996-10-01

    To evaluate the major radiologic features of chronic focal pancreatitis in various imaging studies, with special emphasis on CT and ERCP findings. From 1991 to 1995, twelve patients were pathologically proved to be suffering from focal chronic pancreatitis after pancreatico-duodenectomy;for retrospective evaluation, imaging studies were available for eight(seven men, one woman;mean age 58.9{+-}6.6, range 47 to 67). Clinical, surgical, and radiological findings, including CT(n=8), ultrasound(n=7), ERCP(n=8) and UGI(n=3) were analysed. Seven male patients had suffered from chronic alcoholism for between 20 and 50 years. Serum bilirubin levels were normal in eight patients and alkaline phosphatase levels were normal in seven patients. Serum CA 19-9 levels were normal in all five patients who had undergone preoperative evaluation. Seven patients(87.5%) showed focal enlargement without definable margin on CT, and five of the six lesions detectable on ultrasound(83.3%) were ill defined hypoechoic nodules. Dilated side branches within lesions were seen in five of eight patients(83.3%) on CT and ERCP. Double duct signs were observed in siven(87.5%) patients, and dilated intrahepatic ducts in six(75%), with diameters ranging from 5 to 8mm(average:5.42{+-}1.96mm). The average ratio of pancreatic duct caliber to gland width was 0.33{+-}0.19. None of the patients had calcification within the lesion and one case showed intraductal calcification. None showed perivascular fat obliteration around the superior mesenteric artery or celiac axis. The average biductal distance between abnormal common bile duct and the immediately adjacent pancreatic duct was 4.0{+-}1.15mm. One of three cases who under went a UGI examination showed severe luminal narrowing and mucosal thickening in the second protion of the duodenum, another showed double contour, and the other merely showed widening of the C-loop of the duodenum. Chronic focal pancreatitis mostly demonstrated ill defined focal

  20. CT and ERCP findings of chronic focal pancreatitis

    International Nuclear Information System (INIS)

    Kim, Hee Soo; Lee, Jong Tae; Yoo, Hyung Sik; Kim, Eun Kyeong

    1996-01-01

    To evaluate the major radiologic features of chronic focal pancreatitis in various imaging studies, with special emphasis on CT and ERCP findings. From 1991 to 1995, twelve patients were pathologically proved to be suffering from focal chronic pancreatitis after pancreatico-duodenectomy;for retrospective evaluation, imaging studies were available for eight(seven men, one woman;mean age 58.9±6.6, range 47 to 67). Clinical, surgical, and radiological findings, including CT(n=8), ultrasound(n=7), ERCP(n=8) and UGI(n=3) were analysed. Seven male patients had suffered from chronic alcoholism for between 20 and 50 years. Serum bilirubin levels were normal in eight patients and alkaline phosphatase levels were normal in seven patients. Serum CA 19-9 levels were normal in all five patients who had undergone preoperative evaluation. Seven patients(87.5%) showed focal enlargement without definable margin on CT, and five of the six lesions detectable on ultrasound(83.3%) were ill defined hypoechoic nodules. Dilated side branches within lesions were seen in five of eight patients(83.3%) on CT and ERCP. Double duct signs were observed in siven(87.5%) patients, and dilated intrahepatic ducts in six(75%), with diameters ranging from 5 to 8mm(average:5.42±1.96mm). The average ratio of pancreatic duct caliber to gland width was 0.33±0.19. None of the patients had calcification within the lesion and one case showed intraductal calcification. None showed perivascular fat obliteration around the superior mesenteric artery or celiac axis. The average biductal distance between abnormal common bile duct and the immediately adjacent pancreatic duct was 4.0±1.15mm. One of three cases who under went a UGI examination showed severe luminal narrowing and mucosal thickening in the second protion of the duodenum, another showed double contour, and the other merely showed widening of the C-loop of the duodenum. Chronic focal pancreatitis mostly demonstrated ill defined focal enlargement and

  1. LXW7 ameliorates focal cerebral ischemia injury and attenuates inflammatory responses in activated microglia in rats

    International Nuclear Information System (INIS)

    Fang, T.; Zhou, D.; Lu, L.; Tong, X.; Wu, J.; Yi, L.

    2016-01-01

    Inflammation plays a pivotal role in ischemic stroke, when activated microglia release excessive pro-inflammatory mediators. The inhibition of integrin αvβ3 improves outcomes in rat focal cerebral ischemia models. However, the mechanisms by which microglia are neuroprotective remain unclear. This study evaluated whether post-ischemic treatment with another integrin αvβ3 inhibitor, the cyclic arginine-glycine-aspartic acid (RGD) peptide-cGRGDdvc (LXW7), alleviates cerebral ischemic injury. The anti-inflammatory effect of LXW7 in activated microglia within rat focal cerebral ischemia models was examined. A total of 108 Sprague-Dawley rats (250–280 g) were subjected to middle cerebral artery occlusion (MCAO). After 2 h, the rats were given an intravenous injection of LXW7 (100 μg/kg) or phosphate-buffered saline (PBS). Neurological scores, infarct volumes, brain water content (BWC) and histology alterations were determined. The expressions of pro-inflammatory cytokines [tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β)], and Iba1-positive activated microglia, within peri-ischemic brain tissue, were assessed with ELISA, western blot and immunofluorescence staining. Infarct volumes and BWC were significantly lower in LXW7-treated rats compared to those in the MCAO + PBS (control) group. The LXW7 treatment lowered the expression of pro-inflammatory cytokines. There was a reduction of Iba1-positive activated microglia, and the TNF-α and IL-1β expressions were attenuated. However, there was no difference in the Zea Longa scores between the ischemia and LXW7 groups. The results suggest that LXW7 protected against focal cerebral ischemia and attenuated inflammation in activated microglia. LXW7 may be neuroprotective during acute MCAO-induced brain damage and microglia-related neurodegenerative diseases

  2. LXW7 ameliorates focal cerebral ischemia injury and attenuates inflammatory responses in activated microglia in rats

    Energy Technology Data Exchange (ETDEWEB)

    Fang, T.; Zhou, D.; Lu, L.; Tong, X.; Wu, J.; Yi, L. [Department of Neurology, Shenzhen Hospital, Peking University, Shenzhen (China)

    2016-08-01

    Inflammation plays a pivotal role in ischemic stroke, when activated microglia release excessive pro-inflammatory mediators. The inhibition of integrin αvβ3 improves outcomes in rat focal cerebral ischemia models. However, the mechanisms by which microglia are neuroprotective remain unclear. This study evaluated whether post-ischemic treatment with another integrin αvβ3 inhibitor, the cyclic arginine-glycine-aspartic acid (RGD) peptide-cGRGDdvc (LXW7), alleviates cerebral ischemic injury. The anti-inflammatory effect of LXW7 in activated microglia within rat focal cerebral ischemia models was examined. A total of 108 Sprague-Dawley rats (250–280 g) were subjected to middle cerebral artery occlusion (MCAO). After 2 h, the rats were given an intravenous injection of LXW7 (100 μg/kg) or phosphate-buffered saline (PBS). Neurological scores, infarct volumes, brain water content (BWC) and histology alterations were determined. The expressions of pro-inflammatory cytokines [tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β)], and Iba1-positive activated microglia, within peri-ischemic brain tissue, were assessed with ELISA, western blot and immunofluorescence staining. Infarct volumes and BWC were significantly lower in LXW7-treated rats compared to those in the MCAO + PBS (control) group. The LXW7 treatment lowered the expression of pro-inflammatory cytokines. There was a reduction of Iba1-positive activated microglia, and the TNF-α and IL-1β expressions were attenuated. However, there was no difference in the Zea Longa scores between the ischemia and LXW7 groups. The results suggest that LXW7 protected against focal cerebral ischemia and attenuated inflammation in activated microglia. LXW7 may be neuroprotective during acute MCAO-induced brain damage and microglia-related neurodegenerative diseases.

  3. Oral focal epithelial hyperplasia: report of three cases.

    Science.gov (United States)

    Ghalayani, Parichehr; Tavakoli, Payam; Eftekhari, Mehdi; Haghighi, Mohammad Akhondzadeh

    2015-01-01

    Focal epithelial hyperplasia or Heck's disease is an infrequent asymptomatic condition caused by human papillomavirus types 13 or 32 affecting the mucous membrane of the mouth and is commonly seen in young individuals. Firstly, it was described in Indians and Eskimos, but it exists in various populations. We present three cases of Heck's disease in an Afghan immigrant family group living in Iran that seem to have familial predominance. The disease was identified as oral focal epithelial hyperplasia on the basis of histopathologic and clinical findings. The lesions were reduced significantly after 4 months of good oral hygiene. Dentists should be familiar with the clinical manifestations of these types of lesions that affect the oral cavity. In fact, histopathologic assessment and clinical observation are necessary to establish the diagnosis.

  4. Focal points and principal solutions of linear Hamiltonian systems revisited

    Science.gov (United States)

    Šepitka, Peter; Šimon Hilscher, Roman

    2018-05-01

    In this paper we present a novel view on the principal (and antiprincipal) solutions of linear Hamiltonian systems, as well as on the focal points of their conjoined bases. We present a new and unified theory of principal (and antiprincipal) solutions at a finite point and at infinity, and apply it to obtain new representation of the multiplicities of right and left proper focal points of conjoined bases. We show that these multiplicities can be characterized by the abnormality of the system in a neighborhood of the given point and by the rank of the associated T-matrix from the theory of principal (and antiprincipal) solutions. We also derive some additional important results concerning the representation of T-matrices and associated normalized conjoined bases. The results in this paper are new even for completely controllable linear H