WorldWideScience

Sample records for strictly doe-sr-titled and-issued

  1. Savannah River Site Patented Technologies Summaries

    Energy Technology Data Exchange (ETDEWEB)

    Rabold, D.E.

    1995-07-18

    This information represents SRS`s contribution of the DOE technology information network, an internet service coordinated out of Los Alamos. The information provided is strictly DOE-SR-titled and-issued patented technologies including environmental remediation, robotics, sensors, materials science, biomedical applications, hydrogen, and consumer products.

  2. Strict confluent drawing

    Directory of Open Access Journals (Sweden)

    David Eppstein

    2016-01-01

    Full Text Available We define strict confluent drawing, a form of confluent drawing in which the existence of an edge is indicated by the presence of a smooth path through a system of arcs and junctions (without crossings, and in which such a path, if it exists, must be unique. We prove that it is NP-complete to determine whether a given graph has a strict confluent drawing but polynomial to determine whether it has an outerplanar strict confluent drawing with a fixed vertex ordering (a drawing within a disk, with the vertices placed in a given order on the boundary.

  3. Strictly convex renormings

    Czech Academy of Sciences Publication Activity Database

    Moltó, A.; Orihuela, J.; Troyanski, S.; Zizler, Václav

    2007-01-01

    Roč. 75, č. 3 (2007), s. 647-658 ISSN 0024-6107 R&D Projects: GA AV ČR IAA100190502 Institutional research plan: CEZ:AV0Z10190503 Keywords : strictly convex norms * lattice norm * quasi-diagonal sets Subject RIV: BA - General Mathematics Impact factor: 0.733, year: 2007

  4. Quine's "Strictly Vegetarian" Analyticity

    NARCIS (Netherlands)

    Decock, L.B.

    2017-01-01

    I analyze Quine’s later writings on analyticity from a linguistic point of view. In Word and Object Quine made room for a “strictly vegetarian” notion of analyticity. In later years, he developed this notion into two more precise notions, which I have coined “stimulus analyticity” and “behaviorist

  5. Efficient Strictness Analysis of Haskell

    DEFF Research Database (Denmark)

    Jensen, Kristian Damm; Hjæresen, Peter; Rosendahl, Mads

    1994-01-01

    Strictness analysis has been a living field of investigation since Mycroft's original work in 1980, and is getting increasingly significant with the still wider use of lazy functional programming languages. This paper focuses on an actual implementation of a strictness analyser for Haskell...

  6. Species Protection in the European Union : How Strict is Strict?

    NARCIS (Netherlands)

    Schoukens, Hendrik; Bastmeijer, Kees; Born et al., Charles-Hubert

    2015-01-01

    European Union law to protect wild species of plants and animals is generally considered as ‘strict’. Opponents of nature conservation law often pick the species protection components of the EU Bird Directive and Habitat Directive as a prime example of an unnecessary strict regulatory scheme that

  7. Strictness Analysis for Attribute Grammars

    DEFF Research Database (Denmark)

    Rosendahl, Mads

    1992-01-01

    interpretation of attribute grammars. The framework is used to construct a strictness analysis for attribute grammars. Results of the analysis enable us to transform an attribute grammar such that attributes are evaluated during parsing, if possible. The analysis is proved correct by relating it to a fixpoint...... semantics for attribute grammars. An implementation of the analysis is discussed and some extensions to the analysis are mentioned....

  8. Flexible or Strict Taxonomic Organization?

    DEFF Research Database (Denmark)

    Glückstad, Fumiko Kano; Mørup, Morten

    2012-01-01

    This work compares methods for constructing feature-based ontologies that are supposed to be used for culturally-specific knowledge transfer. The methods to be compared are the Terminological Ontology (TO) [1], a method of constructing ontology based on strict principles and rules, and the Infinite...... Relational Model (IRM) [2], a novel unsupervised machine learning method that learns multi-dimensional relations among concepts and features from loosely structured datasets. These methods are combined with a novel cognitive model, the Bayesian Model of Generalization (BMG) [3] that maps culturally...

  9. Extremely strict ideals in Banach spaces

    Indian Academy of Sciences (India)

    Motivated by the notion of an ideal introduced by Godefroy {\\it et al.} ({\\it Studia Math.} {\\bf 104} (1993) 13–59), in this article, we introduce and study the notion of an extremely strict ideal. For a Poulsen simplex K , we show that the space of affine continuous functions on K is an extremely strict ideal in the space of continuous ...

  10. Hyperbolic spaces are of strictly negative type

    DEFF Research Database (Denmark)

    Hjorth, Poul G.; Kokkendorff, Simon L.; Markvorsen, Steen

    2002-01-01

    We study finite metric spaces with elements picked from, and distances consistent with, ambient Riemannian manifolds. The concepts of negative type and strictly negative type are reviewed, and the conjecture that hyperbolic spaces are of strictly negative type is settled, in the affirmative...

  11. Extremely strict ideals in Banach spaces

    Indian Academy of Sciences (India)

    Abstract. Motivated by the notion of an ideal introduced by Godefroy et al. (Stu- dia Math. 104 (1993) 13–59), in this article, we introduce and study the notion of an extremely strict ideal. For a Poulsen simplex K, we show that the space of affine contin- uous functions on K is an extremely strict ideal in the space of continuous ...

  12. Finite Metric Spaces of Strictly negative Type

    DEFF Research Database (Denmark)

    Hjorth, Poul G.

    If a finite metric space is of strictly negative type then its transfinite diameter is uniquely realized by an infinite extent (“load vector''). Finite metric spaces that have this property include all trees, and all finite subspaces of Euclidean and Hyperbolic spaces. We prove that if the distance...... matrix of a finite metric space is both hypermetric and regular, then it is of strictly negative type. We show that the strictly negative type finite subspaces of spheres are precisely those which do not contain two pairs of antipodal points....

  13. Hyperbolic spaces are of strictly negative type

    DEFF Research Database (Denmark)

    Hjorth, Poul G.; Kokkendorff, Simon L.; Markvorsen, Steen

    2002-01-01

    We study finite metric spaces with elements picked from, and distances consistent with, ambient Riemannian manifolds. The concepts of negative type and strictly negative type are reviewed, and the conjecture that hyperbolic spaces are of strictly negative type is settled, in the affirmative....... The technique of the proof is subsequently applied to show that every compact manifold of negative type must have trivial fundamental group, and to obtain a necessary criterion for product manifolds to be of negative type....

  14. Strictly convex functions on complete Finsler manifolds

    Indian Academy of Sciences (India)

    ... Refresher Courses · Symposia · Live Streaming. Home; Journals; Proceedings – Mathematical Sciences; Volume 126; Issue 4. Strictly convex functions on complete Finsler manifolds. YOE ITOKAWA KATSUHIRO SHIOHAMA BANKTESHWAR TIWARI. Research Article Volume 126 Issue 4 October 2016 pp 623-627 ...

  15. Finite Metric Spaces of Strictly Negative Type

    DEFF Research Database (Denmark)

    Hjorth, Poul; Lisonek, P.; Markvorsen, Steen

    1998-01-01

    We prove that, if a finite metric space is of strictly negative type, then its transfinite diameter is uniquely realized by the infinite extender (load vector). Finite metric spaces that have this property include all spaces on two, three, or four points, all trees, and all finite subspaces of Eu...

  16. Extremely strict ideals in Banach spaces

    Indian Academy of Sciences (India)

    the space of regular Borel measures, it is easy to see that with respect to the projection μ → μ|(0, 1), M is an extremely strict ideal in C([0, 1]) but as the Lebesgue measure is non-atomic, M. ∗. 1 is not the norm closed ..... (Grenoble) 28 (1978) 35–65. [10] Rao T S S R K, On ideals in Banach spaces, Rocky Mountain J. Math.

  17. Strictness Analysis and Denotational Abstract Interpretation

    DEFF Research Database (Denmark)

    Nielson, Flemming

    1988-01-01

    there and this sufices to make the framework applicable to strictness analysis for the lambda-calculus. This shows the possibility of a general theory for the analysis of functional programs and it gives more insight into the relative precision of the various analyses. In particular it is shown that a collecting (static......A theory of abstract interpretation () is developed for a typed lambda-calculus. The typed lambda-calculus may be viewed as the ''static'' part of a two-level denotational metalanguage for which abstract interpretation was developed by ). The present development relaxes a condition imposed...

  18. 7 CFR 28.441 - Strict Middling Yellow Stained Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Yellow Stained Color. 28.441 Section... Strict Middling Yellow Stained Color. Strict Middling Yellow Stained Color is color which is deeper than that of Strict Middling Tinged Color. [57 FR 34498, Aug. 5, 1992] ...

  19. 7 CFR 28.412 - Strict Middling Light Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Light Spotted Color. 28.412 Section 28... Light Spotted Color. Strict Middling Light Spotted Color is color which in spot or color, or both, is between Strict Middling Color and Strict Middling Spotted Color. ...

  20. Geometrical optimization for strictly localized structures

    Science.gov (United States)

    Mo, Yirong

    2003-07-01

    Recently we proposed the block localized wavefunction (BLW) approach which takes the advantages of valence bond theory and molecular orbital theory and defines the wavefunctions for resonance structures based on the assumption that all electrons and orbitals are partitioned into a few subgroups. In this work, we implement the geometrical optimization of the BLW method based on the algorithm proposed by Gianinetti and coworkers. Thus, we can study the conjugation effect on not only the molecular stability, but also the molecular geometry. With this capability, the π conjugation effect in trans-polyenes C2nH2n+2 (n=2-5) as well as in formamide and its analogs are studied by optimizing their delocalized and strictly localized forms with the 6-31G(d) and 6-311+G(d,p) basis sets. Although it has been well presumed that the π resonance shortens the single bonds and lengthens the double bonds with the delocalization of π electrons across the whole line in polyenes, our optimization of the strictly localized structures quantitatively shows that when the conjugation effect is "turned off," the double bond lengths will be identical to the CC bond length in ethylene and the single Csp2-Csp2 bond length will be about 1.513-1.517 Å. In agreement with the classical Hückel theory, the resonance energies in polyenes are approximately in proportion to the number of double bonds. Similarly, resonance is responsible not only for the planarity of formamide, thioformamide, and selenoformamide, but also for the lengthening of the CX (X=O,S,Se) double bond and the shortening of the CN bonds. Although it is assumed that the CX bond polarization decreases in the order of O>S>Se, the π electronic delocalization increases in the opposite order, i.e., formamide

  1. From Regular to Strictly Locally Testable Languages

    Directory of Open Access Journals (Sweden)

    Stefano Crespi Reghizzi

    2011-08-01

    Full Text Available A classical result (often credited to Y. Medvedev states that every language recognized by a finite automaton is the homomorphic image of a local language, over a much larger so-called local alphabet, namely the alphabet of the edges of the transition graph. Local languages are characterized by the value k=2 of the sliding window width in the McNaughton and Papert's infinite hierarchy of strictly locally testable languages (k-slt. We generalize Medvedev's result in a new direction, studying the relationship between the width and the alphabetic ratio telling how much larger the local alphabet is. We prove that every regular language is the image of a k-slt language on an alphabet of doubled size, where the width logarithmically depends on the automaton size, and we exhibit regular languages for which any smaller alphabetic ratio is insufficient. More generally, we express the trade-off between alphabetic ratio and width as a mathematical relation derived from a careful encoding of the states. At last we mention some directions for theoretical development and application.

  2. 7 CFR 28.404 - Strict Low Middling Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Low Middling Color. 28.404 Section 28.404... for the Color Grade of American Upland Cotton § 28.404 Strict Low Middling Color. Strict Low Middling Color is color which is within the range represented by a set of samples in the custody of the United...

  3. 7 CFR 28.406 - Strict Good Ordinary Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Good Ordinary Color. 28.406 Section 28.406... for the Color Grade of American Upland Cotton § 28.406 Strict Good Ordinary Color. Strict Good Ordinary Color is color which is within the range represented by a set of samples in the custody of the...

  4. 7 CFR 28.402 - Strict Middling Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Color. 28.402 Section 28.402... for the Color Grade of American Upland Cotton § 28.402 Strict Middling Color. Strict Middling Color is color which is within the range represented by a set of samples in the custody of the United States...

  5. Mammalian evolution may not be strictly bifurcating.

    Science.gov (United States)

    Hallström, Björn M; Janke, Axel

    2010-12-01

    The massive amount of genomic sequence data that is now available for analyzing evolutionary relationships among 31 placental mammals reduces the stochastic error in phylogenetic analyses to virtually zero. One would expect that this would make it possible to finally resolve controversial branches in the placental mammalian tree. We analyzed a 2,863,797 nucleotide-long alignment (3,364 genes) from 31 placental mammals for reconstructing their evolution. Most placental mammalian relationships were resolved, and a consensus of their evolution is emerging. However, certain branches remain difficult or virtually impossible to resolve. These branches are characterized by short divergence times in the order of 1-4 million years. Computer simulations based on parameters from the real data show that as little as about 12,500 amino acid sites could be sufficient to confidently resolve short branches as old as about 90 million years ago (Ma). Thus, the amount of sequence data should no longer be a limiting factor in resolving the relationships among placental mammals. The timing of the early radiation of placental mammals coincides with a period of climate warming some 100-80 Ma and with continental fragmentation. These global processes may have triggered the rapid diversification of placental mammals. However, the rapid radiations of certain mammalian groups complicate phylogenetic analyses, possibly due to incomplete lineage sorting and introgression. These speciation-related processes led to a mosaic genome and conflicting phylogenetic signals. Split network methods are ideal for visualizing these problematic branches and can therefore depict data conflict and possibly the true evolutionary history better than strictly bifurcating trees. Given the timing of tectonics, of placental mammalian divergences, and the fossil record, a Laurasian rather than Gondwanan origin of placental mammals seems the most parsimonious explanation.

  6. Modal Inclusion Logic: Being Lax is Simpler than Being Strict

    DEFF Research Database (Denmark)

    Hella, Lauri; Kuusisto, Antti Johannes; Meier, Arne

    2015-01-01

    We investigate the computational complexity of the satisfiability problem of modal inclusion logic. We distinguish two variants of the problem: one for strict and another one for lax semantics. The complexity of the lax version turns out to be complete for EXPTIME, whereas with strict semantics...

  7. 7 CFR 28.431 - Strict Middling Tinged Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Tinged Color. 28.431 Section 28.431 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Color. Strict Middling Tinged Color is color which is better than Middling Tinged Color. ...

  8. 7 CFR 28.433 - Strict Low Middling Tinged Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Low Middling Tinged Color. 28.433 Section 28.433 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Tinged Color. Strict Low Middling Tinged Color is color which is within the range represented by a set of...

  9. 7 CFR 28.424 - Strict Low Middling Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Low Middling Spotted Color. 28.424 Section 28.424 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Spotted Color. Strict Low Middling Spotted Color is color which is within the range represented by a set...

  10. 7 CFR 28.426 - Strict Good Ordinary Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Good Ordinary Spotted Color. 28.426 Section 28.426 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Spotted Color. Strict Good Ordinary Spotted Color is color which is within the range represented by a set...

  11. 7 CFR 28.422 - Strict Middling Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Spotted Color. 28.422 Section 28.422 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Color. Strict Middling Spotted Color is color which is within the range represented by a set of samples...

  12. Strictly-regular number system and data structures

    DEFF Research Database (Denmark)

    Elmasry, Amr Ahmed Abd Elmoneim; Jensen, Claus; Katajainen, Jyrki

    2010-01-01

    We introduce a new number system that we call the strictly-regular system, which efficiently supports the operations: digit-increment, digit-decrement, cut, concatenate, and add. Compared to other number systems, the strictly-regular system has distinguishable properties. It is superior to the re...

  13. Strategy and Aspects of Monitoring / Control Strictly in Coordinated Subsystems

    Directory of Open Access Journals (Sweden)

    William José Borges

    2012-06-01

    Full Text Available This paper aims to discuss the approach structures of the strictly coordinated theoretical framework developed by Zylbersztajn and Farina (1999 as an expanded perspective of the firm, taking into account the food supply chains as an extension of the nexus of contracts proposed by Coase (1937 and taken up by Williamson (1985. The structures stand out as strictly coordinated. Zylbersztajn and Farina (1999 turn to identifying points of common interests that encourage firms to promote contracts between themselves in a strictly coordinated way, considering the degree of asset specificity involved in the transaction and the competitive forces that determine the search for strategic positioning organizations to achieve sustainable superior results.

  14. Strict finitism and the logic of mathematical applications

    CERN Document Server

    Ye, Feng

    2011-01-01

    Exploring the logic behind applied mathematics to the physical world, this volume illustrates how radical naturalism, nominalism and strict finitism can account for the applications of classical mathematics in current theories about natural phenomena.

  15. Strict monotonicity and unique continuation of the biharmonic operator

    Directory of Open Access Journals (Sweden)

    Najib Tsouli

    2012-01-01

    Full Text Available In this paper, we will show that the strict monotonicity of the eigenvalues of the biharmonic operator holds if and only if some unique continuation property is satisfied by the corresponding eigenfunctions.

  16. Two examples of non strictly convex large deviations

    OpenAIRE

    De Marco, Stefano; Jacquier, Antoine; Roome, Patrick

    2016-01-01

    We present two examples of a large deviations principle where the rate function is not strictly convex. This is motivated by a model used in mathematical finance (the Heston model), and adds a new item to the zoology of non strictly convex large deviations. For one of these examples, we show that the rate function of the Cramer-type of large deviations coincides with that of the Freidlin-Wentzell when contraction principles are applied.

  17. Strictly contractive quantum channels and physically realizable quantum computers

    International Nuclear Information System (INIS)

    Raginsky, Maxim

    2002-01-01

    We study the robustness of quantum computers under the influence of errors modeled by strictly contractive channels. A channel T is defined to be strictly contractive if, for any pair of density operators ρ, σ in its domain, parallel Tρ-Tσ parallel 1 ≤k parallel ρ-σ parallel 1 for some 0≤k 1 denotes the trace norm). In other words, strictly contractive channels render the states of the computer less distinguishable in the sense of quantum detection theory. Starting from the premise that all experimental procedures can be carried out with finite precision, we argue that there exists a physically meaningful connection between strictly contractive channels and errors in physically realizable quantum computers. We show that, in the absence of error correction, sensitivity of quantum memories and computers to strictly contractive errors grows exponentially with storage time and computation time, respectively, and depends only on the constant k and the measurement precision. We prove that strict contractivity rules out the possibility of perfect error correction, and give an argument that approximate error correction, which covers previous work on fault-tolerant quantum computation as a special case, is possible

  18. Convergence theorems for strictly hemi-contractive maps

    International Nuclear Information System (INIS)

    Chidume, C.E.; Osilike, M.O.

    1992-04-01

    It is proved that each of two well-known fixed point iteration methods (the Mann and the Ishikawa iteration methods) converges strongly to the fixed point of strictly hemi-contractive map in real Banach spaces with property (U, λ, m+1,m), λ is an element of R, m is an element of IN. The class of strictly hemi-contractive maps includes all strictly pseudo-contractive maps with nonempty fixed point sets; and Banach spaces with property (U, λ, m+1, m), λ is an element of R, m is an element of IN include the L p (or l p ) spaces, p≥2. Our theorems generalize important known results. (author). 22 refs

  19. Mann iteration with errors for strictly pseudo-contractive mappings ...

    African Journals Online (AJOL)

    It is well known that any fixed point of a Lipschitzian strictly pseudo-contractive self mapping of a nonempty closed convex and bounded subset K of a Banach space X is unique [6] and may be norm approximated by an iterative procedure. In this paper, we show that Mann iteration with errors can be used to approximate the ...

  20. Dominated operators, absolutely summing operators and the strict ...

    African Journals Online (AJOL)

    b(X;E) be the space of all E-valued bounded continuous functions on X, equipped with the strict topology β. We study dominated and absolutely summing operators T : Cb(X;E) → F. We derive that if X is a locally compact Hausdorff space and E ...

  1. Convergence of GAOR Iterative Method with Strictly Diagonally Dominant Matrices

    Directory of Open Access Journals (Sweden)

    Guangbin Wang

    2011-01-01

    Full Text Available We discuss the convergence of GAOR method for linear systems with strictly diagonally dominant matrices. Moreover, we show that our results are better than ones of Darvishi and Hessari (2006, Tian et al. (2008 by using three numerical examples.

  2. Runaway selection for cooperation and strict-and-severe punishment.

    Science.gov (United States)

    Nakamaru, Mayuko; Dieckmann, Ulf

    2009-03-07

    Punishing defectors is an important means of stabilizing cooperation. When levels of cooperation and punishment are continuous, individuals must employ suitable social standards for defining defectors and for determining punishment levels. Here we investigate the evolution of a social reaction norm, or psychological response function, for determining the punishment level meted out by individuals in dependence on the cooperation level exhibited by their neighbors in a lattice-structured population. We find that (1) cooperation and punishment can undergo runaway selection, with evolution towards enhanced cooperation and an ever more demanding punishment reaction norm mutually reinforcing each other; (2) this mechanism works best when punishment is strict, so that ambiguities in defining defectors are small; (3) when the strictness of punishment can adapt jointly with the threshold and severity of punishment, evolution favors the strict-and-severe punishment of individuals who offer slightly less than average cooperation levels; (4) strict-and-severe punishment naturally evolves and leads to much enhanced cooperation when cooperation without punishment would be weak and neither cooperation nor punishment are too costly; and (5) such evolutionary dynamics enable the bootstrapping of cooperation and punishment, through which defectors who never punish gradually and steadily evolve into cooperators who punish those they define as defectors.

  3. Dominance on Strict Triangular Norms and Mulholland Inequality

    Czech Academy of Sciences Publication Activity Database

    Petrík, Milan

    2018-01-01

    Roč. 335, 15 March (2018), s. 3-17 ISSN 0165-0114 R&D Projects: GA ČR GJ15-07724Y Institutional support: RVO:67985807 Keywords : dominance relation * Mulholland inequality * strict triangular norm * transitivity Subject RIV: BA - General Mathematics Impact factor: 2.718, year: 2016

  4. Relaxation Methods for Strictly Convex Regularizations of Piecewise Linear Programs

    International Nuclear Information System (INIS)

    Kiwiel, K. C.

    1998-01-01

    We give an algorithm for minimizing the sum of a strictly convex function and a convex piecewise linear function. It extends several dual coordinate ascent methods for large-scale linearly constrained problems that occur in entropy maximization, quadratic programming, and network flows. In particular, it may solve exact penalty versions of such (possibly inconsistent) problems, and subproblems of bundle methods for nondifferentiable optimization. It is simple, can exploit sparsity, and in certain cases is highly parallelizable. Its global convergence is established in the recent framework of B -functions (generalized Bregman functions)

  5. Non-strictly black body spectrum from the tunnelling mechanism

    International Nuclear Information System (INIS)

    Corda, Christian

    2013-01-01

    The tunnelling mechanism is widely used to explain Hawking radiation. However, in many cases the analysis used to obtain the Hawking temperature only involves comparing the emission probability for an outgoing particle with the Boltzmann factor. Banerjee and Majhi improved this approach by explicitly finding a black body spectrum associated with black holes. Their result, obtained using a reformulation of the tunnelling mechanism, is in contrast to that of Parikh and Wilczek, who found an emission probability that is compatible with a non-strictly thermal spectrum. Using the recently identified effective state for a black hole, we solve this contradiction via a slight modification of the analysis by Banerjee and Majhi. The final result is a non-strictly black body spectrum from the tunnelling mechanism. We also show that for an effective temperature, we can express the corresponding effective metric using Hawking’s periodicity arguments. Potential important implications for the black hole information puzzle are discussed. -- Highlights: •We review an important result by Banerjee and Majhi on the tunnelling mechanism in the framework of Hawking radiation. •This result is in contrast to another result reported by Parikh and Wilczek. •We introduce the effective state of a black hole. •We explain the contrast via a slight modification of the analysis by Banerjee and Majhi. •We discuss potential important implications for the black hole information puzzle

  6. Effects of a strict cutoff on Quantum Field Theory

    International Nuclear Information System (INIS)

    Sturnfield, J.F.

    1987-01-01

    Standard Quantum Field Theory has a number of integrals which are infinite. Although these are eliminated for some cases by renormalization, this aspect of the theory is not fully satisfactory. A number of theories with fundamental lengths have been introduced as alternatives and it would be useful to be able to distinguish between them. In particular, the effects that a strict cutoff would have on Quantum Field Theory is studied. It is noted that care must be taken in the method used to apply a strict cutoff. This lead to considering a theory where the cutoffs are defined by restricting each internal line. This theory is only piece-wise analytic. The resulting scattering matrix is frame dependent, yet the theory still satisfies the special relativity view that all frames are subjectively identical. The renormalization of this theory is finite. The change in mass from the electron self-energy will be a spinor operator. The main distinctions of this theory from standard theory will occur at super high energies. New poles and resonances which arise from new endpoint singularities will be found. The locations of these singularities will be frame dependent. Some of these singularities will correspond to creations or interactions of the normal particles with tachyons. It will be shown that for the one loop diagram, the form of the cutoff singularities are closely related to the standard singularities. When there is more than one loop, there can appear some new type of behavior. In particular, a cube root type of behavior in the two loop self-energy diagram will be found. Also the asymptotic behavior of the ladder diagram is studied

  7. 7 CFR 28.414 - Strict Low Middling Light Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... CONTAINER REGULATIONS COTTON CLASSING, TESTING, AND STANDARDS Standards Light Spotted Cotton § 28.414 Strict Low Middling Light Spotted Color. Strict Low Middling Light Spotted Color is color which in spot or...

  8. On N. Chomsky’s strict subcategorization of verbs

    Directory of Open Access Journals (Sweden)

    Janez Orešnik

    1966-12-01

    Full Text Available This paper studies the so-called strict subcategorization rules, and the theory associated with them, in the transformational grammar of. Erigl·ish as proposed by Noarn Chomsky in his Aspects. The syntactic component of English transformational grammar consists of two mutually ordered parts, viz., the base and the transformational subcomponents. The initial part of the base are the so-called categorial rules, which are of almost exclusive interest to us here. Their primary task is to generate what are usually called basic sentence patterns, and will here, with Chomsky (Aspects, p.ll3, be designated with the expression, frames of category symbols.- The rules of the transformational subcomponent modify, in various ways, the frames generated by the base. For several reasons - one of them being that the correct work of the transformational subcomponent quite often depends on the kind of lexical items with which the syntactic positions in the frames of category symbols have been filled, the lexical items must be introduced from the lexicon into the empty positions in the frames before the rules of the transformational subcomponent can be allowed to modify the frames.

  9. Managing Hanford Site solid waste through strict acceptance criteria

    International Nuclear Information System (INIS)

    Jasen, W.G.; Pierce, R.D.; Willis, N.P.

    1993-02-01

    Various types of waste have been generated during the 50-year history of the Hanford Site. Regulatory changes in the last 20 years have provided the emphasis for better management of these wastes. Interpretations of the Atomic Energy Act of 1954 (AEA) and the Resource Conservation and Recovery Act of 1976 (RCRA) have led to the definition of a group of wastes called radioactive mixed wastes (RMW). As a result of the radioactive and hazardous properties of these wastes, strict management programs have been implemented for the management of these wastes. Solid waste management is accomplished through a systems performance approach to waste management that used best-demonstrated available technology (BDAT) and best management practices. The solid waste program at the Hanford Site strives to integrate all aspects of management relative to the treatment, storage and disposal (TSD) of solid waste. Often there are many competing and important needs. It is a difficult task to balance these needs in a manner that is both equitable and productive. Management science is used to help the process of making decisions. Tools used to support the decision making process include five-year planning, cost estimating, resource allocation, performance assessment, waste volume forecasts, input/output models, and waste acceptance criteria. The purpose of this document is to describe how one of these tools, waste acceptance criteria, has helped the Hanford Site manage solid wastes

  10. Effects of strict prolonged bed rest on cardiorespiratory fitness

    DEFF Research Database (Denmark)

    Ried-Larsen, Mathias; Aarts, Hugo M; Joyner, Michael J

    2017-01-01

    with larger declines in V̇o2max). Furthermore, the systematic review revealed a gap in the knowledge about the cardiovascular response to extreme physical inactivity, particularly in older subjects and women of any age group. In addition to its relevance to spaceflight, this lack of data has significant....... Since 1949, 80 studies with a total of 949 participants (>90% men) have been published with data on strict bed rest and V̇o2max The studies were conducted mainly in young participants [median age (interquartile range) 24.5 (22.4-34.0) yr]. The duration of bed rest ranged from 1 to 90 days. V̇o2max...... declined linearly across bed rest duration. No statistical difference in the decline among studies reporting V̇o2max as l/min (-0.3% per day) compared with studies reporting V̇o2max normalized to body weight (ml·kg-1·min-1; -0.43% per day) was observed. Although both total body weight and lean body mass...

  11. Fixed point iterations for strictly hemi-contractive maps in uniformly smooth Banach spaces

    International Nuclear Information System (INIS)

    Chidume, C.E.; Osilike, M.O.

    1993-05-01

    It is proved that the Mann iteration process converges strongly to the fixed point of a strictly hemi-contractive map in real uniformly smooth Banach spaces. The class of strictly hemi-contractive maps includes all strictly pseudo-contractive maps with nonempty fixed point sets. A related result deals with the Ishikawa iteration scheme when the mapping is Lipschitzian and strictly hemi-contractive. Our theorems generalize important known results. (author). 29 refs

  12. Strict or graduated punishment? Effect of punishment strictness on the evolution of cooperation in continuous public goods games.

    Directory of Open Access Journals (Sweden)

    Hajime Shimao

    Full Text Available Whether costly punishment encourages cooperation is one of the principal questions in studies on the evolution of cooperation and social sciences. In society, punishment helps deter people from flouting rules in institutions. Specifically, graduated punishment is a design principle for long-enduring common-pool resource institutions. In this study, we investigate whether graduated punishment can promote a higher cooperation level when each individual plays the public goods game and has the opportunity to punish others whose cooperation levels fall below the punisher's threshold. We then examine how spatial structure affects evolutionary dynamics when each individual dies inversely proportional to the game score resulting from the social interaction and another player is randomly chosen from the population to produce offspring to fill the empty site created after a player's death. Our evolutionary simulation outcomes demonstrate that stricter punishment promotes increased cooperation more than graduated punishment in a spatially structured population, whereas graduated punishment increases cooperation more than strict punishment when players interact with randomly chosen opponents from the population. The mathematical analysis also supports the results.

  13. Strict or Graduated Punishment? Effect of Punishment Strictness on the Evolution of Cooperation in Continuous Public Goods Games

    Science.gov (United States)

    Shimao, Hajime; Nakamaru, Mayuko

    2013-01-01

    Whether costly punishment encourages cooperation is one of the principal questions in studies on the evolution of cooperation and social sciences. In society, punishment helps deter people from flouting rules in institutions. Specifically, graduated punishment is a design principle for long-enduring common-pool resource institutions. In this study, we investigate whether graduated punishment can promote a higher cooperation level when each individual plays the public goods game and has the opportunity to punish others whose cooperation levels fall below the punisher’s threshold. We then examine how spatial structure affects evolutionary dynamics when each individual dies inversely proportional to the game score resulting from the social interaction and another player is randomly chosen from the population to produce offspring to fill the empty site created after a player’s death. Our evolutionary simulation outcomes demonstrate that stricter punishment promotes increased cooperation more than graduated punishment in a spatially structured population, whereas graduated punishment increases cooperation more than strict punishment when players interact with randomly chosen opponents from the population. The mathematical analysis also supports the results. PMID:23555826

  14. The Success Rate of Initial {sup 131I} Ablation in Differentiated Thyroid Cancer: Comparison Between Less strict and Very Strict Low Iodine Diets

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Ik Dong; Kim, Sung Hoon; Seo, Ye Young; Oh, Jin Kyoung; O, Joo Hyun; Chung, Soo Kyo [The Catholic Univ. of Korea, Seoul (Korea, Republic of)

    2012-03-15

    To decrease the risk of recurrence or metastasis in differentiated thyroid cancer (DTC), selected patients receive radioactive iodine ablation of remnant thyroid tissue or tumor. A low iodine diet can enhance uptake of radioactive iodine. We compared the success rates of radioactive iodine ablation therapy in patients who followed two different low iodine diets (LIDs). The success rates of postsurgical radioactive iodine ablation in DTC patients receiving empiric doses of 150 mCi were retrospectively reviewed. First-time radioactive iodine ablation therapy was done in 71 patients following less strict LID. Less strict LID restricted seafood, iodized salt, egg yolk, dairy products, processed meat, instant prepared meals, and multivitamins. Very strict LID additionally restricted rice, freshwater fish, spinach, and soybean products. Radioactive iodine ablation therapy was considered successful when follow up {sup 123I} whole body scan was negative and stimulated serum thyroglobulin level was less than 2.0 ng/mL. The success rate of patients following less strict LID was 80.3% and for very strict LID 75.6%. There was no statistically significant difference in the success rates between the two LID groups (P=0.48). Very strict LID may not contribute to improving the success rate of initial radioactive iodine ablation therapy at the cost of great inconvenience to the patient.

  15. Validation of an automatic diagnosis of strict left bundle branch block criteria using 12-lead electrocardiograms

    DEFF Research Database (Denmark)

    Xia, Xiaojuan; Ruwald, Anne-Christine; Ruwald, Martin H

    2017-01-01

    AIMS: Strict left bundle branch block (LBBB) criteria were recently proposed to identify LBBB patients to benefit most from cardiac resynchronization therapy (CRT). The aim of our study was to automate identification of strict LBBB in order to facilitate its broader application. METHODS: We devel...

  16. 7 CFR 28.416 - Strict Good Ordinary Light Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... CONTAINER REGULATIONS COTTON CLASSING, TESTING, AND STANDARDS Standards Light Spotted Cotton § 28.416 Strict Good Ordinary Light Spotted Color. Strict Good Ordinary Light Spotted Color is color which in spot or... Cotton Source: 57 FR 34498, Aug. 5, 1992, unless otherwise noted. ...

  17. Synchronization control of cross-strict feedback hyperchaotic system based on cross active backstepping design

    International Nuclear Information System (INIS)

    Wang Jing; Gao Jinfeng; Ma Xikui

    2007-01-01

    This Letter presents a novel cross active backstepping design method for synchronization control of cross-strict feedback hyperchaotic system, in which the ordinary backstepping design is unavailable. The proposed control method, combining backstepping design and active control approach, extends the application of backstepping technique in chaos control. Based on this method, different combinations of controllers can be designed to meet the needs of different applications. The proposed method is applied to achieve chaos synchronization of two identical cross-strict feedback hyperchaotic systems. Also it is used to implement synchronization between cross-strict feedback hyperchaotic system and Roessler hyperchaotic system. Numerical examples illustrate the validity of the control method

  18. The Effect of Strict Segregation on Pseudomonas aeruginosa in Cystic Fibrosis Patients

    NARCIS (Netherlands)

    van Mansfeld, Rosa; de Vrankrijker, Angelica; Brimicombe, Roland; Heijerman, Harry; Teding van Berkhout, Ferdinand; Spitoni, Cristian|info:eu-repo/dai/nl/304625957; Grave, Sanne; van der Ent, Cornelis; Wolfs, Tom; Willems, Rob; Bonten, Marc

    2016-01-01

    INTRODUCTION: Segregation of patients with cystic fibrosis (CF) was implemented to prevent chronic infection with epidemic Pseudomonas aeruginosa strains with presumed detrimental clinical effects, but its effectiveness has not been carefully evaluated. METHODS: The effect of strict segregation on

  19. Strict deformation quantization for actions of a class of symplectic lie groups

    International Nuclear Information System (INIS)

    Bieliavsky, Pierre; Massar, Marc

    2002-01-01

    We present explicit universal strict deformation quantization formulae for actions of Iwasawa subgroups AN of SN(1, n). This answers a question raised by Rieffel in [Contemp. Math. 228 (1998), 315]. (author)

  20. Strict optical orthogonal codes for purely asynchronous code-division multiple-access applications

    Science.gov (United States)

    Zhang, Jian-Guo

    1996-12-01

    Strict optical orthogonal codes are presented for purely asynchronous optical code-division multiple-access (CDMA) applications. The proposed code can strictly guarantee the peaks of its cross-correlation functions and the sidelobes of any of its autocorrelation functions to have a value of 1 in purely asynchronous data communications. The basic theory of the proposed codes is given. An experiment on optical CDMA systems is also demonstrated to verify the characteristics of the proposed code.

  1. Plant use in the medicinal practices known as "strict diets" in Chazuta valley (Peruvian Amazon).

    Science.gov (United States)

    Sanz-Biset, Jaume; Cañigueral, Salvador

    2011-09-01

    Strict diets are traditional medicinal practices where plant remedies are consumed with nearly fasting and with some sort of social seclusion. The aim of this work was to describe these practices of Chazuta and the use of plants within, as well as to analyse the possible functions of the last. The information was obtained through interviews to the 6.3% of the district rural adult population (140 individuals, 75% of which was considered Quechua). In total, 122 strict diets were recorded and 106 different plant species were reported to be used. Strict diets present a characteristic structure and plant use. The main effects reported in strict diets were antinflammatory, antiinfective, brain function alteration and depuration. Strict diets are well structured traditional medicinal practices, also with a symbolic significance in the life cycle of chazutian men. Plants used in strict diets can contribute to the main effects through antinflammation, antiinfective actions, psychoactivity and depurative related activities. The correlation between literature evidence of activity of most used plants and effects reported for the correspondent diet (i.e. in which the plant was used) are 36% for antinflammatory activity, 29% for antimicrobial activity, 18% for psychoactivity and 5% for depurative related activities. The percentages go to 77%, 64%, 73% and 32%, respectively, when literature evidences on related taxa are also considered. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  2. Actions of a separately strict cpo-monoid on pointed directed complete posets

    Directory of Open Access Journals (Sweden)

    Halimeh Moghbeli Damaneh

    2015-07-01

    Full Text Available ‎ In the present article‎, ‎we study some categorical properties of the category {$bf‎ Cpo_{Sep}$-$S$} of all {separately strict $S$-cpo's}; cpo's equipped with‎ a compatible right action of a separately strict cpo-monoid $S$ which is‎ strict continuous in each component‎. ‎In particular‎, we show that this category is reflective and coreflective in the‎ category of $S$-cpo's‎, ‎find the free and cofree functors‎, characterize products and coproducts‎. ‎Furthermore‎, ‎epimorphisms and‎  monomorphisms in {$bf Cpo_{Sep}$-$S$} are studied‎, ‎and show that‎ {$bf Cpo_{Sep}$-$S$} is not cartesian closed‎.

  3. The photon is no strict particle and nonlocality is far from being proven

    Energy Technology Data Exchange (ETDEWEB)

    Greulich, Karl Otto [Fritz Lipmann Institut, Jena (Germany)

    2010-07-01

    Two aspects of philosophical discussions on physics are the wave particle dualism and non locality including entanglement. However the strict particle aspect of the photon, in the common sense view, has never been proven. The accumulation time argument, the only experimental verification of a strictly particle like photon, has so far not yet been satisfied. Also, experiments thought to prove nonlocality have loophole which have so far not yet been safely closed, and now an even more serious loophole emerges. Thus, also nonlocality cannot be seen as proven. This demands some fine tuning of philosophical discussions on critical experiments in physics.

  4. More strictly protected areas are not necessarily more protective: evidence from Bolivia, Costa Rica, Indonesia, and Thailand

    International Nuclear Information System (INIS)

    Ferraro, Paul J; Hanauer, Merlin M; Miteva, Daniela A; Pattanayak, Subhrendu K; Canavire-Bacarreza, Gustavo Javier; Sims, Katharine R E

    2013-01-01

    National parks and other protected areas are at the forefront of global efforts to protect biodiversity and ecosystem services. However, not all protection is equal. Some areas are assigned strict legal protection that permits few extractive human uses. Other protected area designations permit a wider range of uses. Whether strictly protected areas are more effective in achieving environmental objectives is an empirical question: although strictly protected areas legally permit less anthropogenic disturbance, the social conflicts associated with assigning strict protection may lead politicians to assign strict protection to less-threatened areas and may lead citizens or enforcement agents to ignore the strict legal restrictions. We contrast the impacts of strictly and less strictly protected areas in four countries using IUCN designations to measure de jure strictness, data on deforestation to measure outcomes, and a quasi-experimental design to estimate impacts. On average, stricter protection reduced deforestation rates more than less strict protection, but the additional impact was not always large and sometimes arose because of where stricter protection was assigned rather than regulatory strictness per se. We also show that, in protected area studies contrasting y management regimes, there are y 2 policy-relevant impacts, rather than only y, as earlier studies have implied. (letter)

  5. Strict Monotonicity and Unique Continuation for the Third-Order Spectrum of Biharmonic Operator

    Directory of Open Access Journals (Sweden)

    Khalil Ben Haddouch

    2012-01-01

    Full Text Available We will study the spectrum for the biharmonic operator involving the laplacian and the gradient of the laplacian with weight, which we call third-order spectrum. We will show that the strict monotonicity of the eigenvalues of the operator , where , holds if some unique continuation property is satisfied by the corresponding eigenfunctions.

  6. "Let the Master Respond": Should Schools Be Strictly Liable When Employees Sexually Abuse Children?

    Science.gov (United States)

    Fossey, Richard; DeMitchell, Todd

    Although sexual abuse against children is a problem in the public schools, school officials have generally not acted aggressively to stop it. This paper argues for a strict liability standard--the assessment of liability without fault--against a school district in cases of student sexual abuse by a school employee. Part 1 explores the principle of…

  7. Detection of low numbers of microplastics in North Sea fish using strict quality assurance criteria

    NARCIS (Netherlands)

    Hermsen, E.; Pompe, R.; Besseling, E.; Koelmans, A.A.

    2017-01-01

    We investigated 400 individual fish of four North Sea species: Atlantic Herring, Sprat, Common Dab, and Whiting on ingestion of > 20 μm microplastic. Strict quality assurance criteria were followed in order to control contamination during the study. Two plastic particles were found in only 1 (a

  8. History, administration, goals, values, and long-term data of Russia's strictly protected scientific nature reserves

    Science.gov (United States)

    Martin A. Spetich; Anna E. Kvashnina; Y.D. Nukhimovskya; Olin E. Jr. Rhodes

    2009-01-01

    One of the most comprehensive attempts at biodiversity conservation in Russia and the former Soviet Union has been the establishment of an extensive network of protected natural areas. Among all types of protected areas in Russia, zapovedniks (strictly protected scientific preserve) have been the most effective in protecting biodiversity at the ecosystem scale. Russia...

  9. The Preventive Effect of Strict Gun Control Laws on Suicide and Homicide.

    Science.gov (United States)

    Lester, David; Murrell, Mary E.

    1982-01-01

    Examined state gun control laws and used a multidimensional scaling technique to study the relationship of strictness and death rates. Results showed states with stricter laws had lower suicide rates by firearms but higher rates by other means. No effect on homicide was found. (JAC)

  10. A Criterium for the Strict Positivity of the Density of the Law of a Poisson Process

    Directory of Open Access Journals (Sweden)

    Léandre Rémi

    2011-01-01

    Full Text Available We translate in semigroup theory our result (Léandre, 1990 giving a necessary condition so that the law of a Markov process with jumps could have a strictly positive density. This result express, that we have to jump in a finite number of jumps in a "submersive" way from the starting point to the end point if the density of the jump process is strictly positive in . We use the Malliavin Calculus of Bismut type of (Léandre, (2008;2010 translated in semi-group theory as a tool, and the interpretation in semi-group theory of some classical results of the stochastic analysis for Poisson process as, for instance, the formula giving the law of a compound Poisson process.

  11. The effect of 8 days of strict bed rest on the incretin effect in healthy volunteers

    DEFF Research Database (Denmark)

    Nielsen, Signe Tellerup; Harder-Lauridsen, Nina Majlund; Benatti, Fabiana Braga

    2016-01-01

    in the levels of GLP-1 and Glucagon. Bed rest led to a mean loss of 2.4 kg of fat-free mass, and induced insulin resistance evaluated by the Matsuda index, but did not affect the incretin effect (P = 0.6). In conclusion, 8 days of bed rest induces insulin resistance, but we did not see evidence of an associated......Bed rest and physical inactivity are the consequences of hospital admission for many patients. Physical inactivity induces changes in glucose metabolism, but its effect on the incretin effect, which is reduced in, e.g., Type 2 diabetes, is unknown. To investigate how 8 days of strict bed rest...... affects the incretin effect, 10 healthy nonobese male volunteers underwent 8 days of strict bed rest. Before and after the intervention, all volunteers underwent an oral glucose tolerance test (OGTT) followed by an intravenous glucose infusion (IVGI) on the following day to mimic the blood glucose profile...

  12. Detection of low numbers of microplastics in North Sea fish using strict quality assurance criteria.

    Science.gov (United States)

    Hermsen, Enya; Pompe, Renske; Besseling, Ellen; Koelmans, Albert A

    2017-09-15

    We investigated 400 individual fish of four North Sea species: Atlantic Herring, Sprat, Common Dab, and Whiting on ingestion of >20μm microplastic. Strict quality assurance criteria were followed in order to control contamination during the study. Two plastic particles were found in only 1 (a Sprat) out of 400 individuals (0.25%, with a 95% confidence interval of 0.09-1.1%). The particles were identified to consist of polymethylmethacrylate (PMMA) through FTIR spectroscopy. No contamination occurred during the study, showing the method applied to be suitable for microplastic ingestion studies in biota. We discuss the low particle count for North Sea fish with those in other studies and suggest a relation between reported particle count and degree of quality assurance applied. Microplastic ingestion by fish may be less common than thought initially, with low incidence shown in this study, and other studies adhering to strict quality assurance criteria. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. A strict anaerobic extreme thermophilic hydrogen-producing culture enriched from digested household waste

    DEFF Research Database (Denmark)

    Karakashev, Dimitar Borisov; Kotay, Shireen Meher; Trably, Eric

    2009-01-01

    sources. Growth on glucose produced acetate, H-2 and carbon dioxide. Maximal H-2 production rate on glucose was 1.1 mmol l(-1) h(-1) with a maximum H-2 yield of 1.9 mole H-2 per mole glucose. 16S ribosomal DNA clone library analyses showed that the culture members were phylogenetically affiliated......The aim of this study was to enrich, characterize and identify strict anaerobic extreme thermophilic hydrogen (H-2) producers from digested household solid wastes. A strict anaerobic extreme thermophilic H-2 producing bacterial culture was enriched from a lab-scale digester treating household...... wastes at 70 degrees C. The enriched mixed culture consisted of two rod-shaped bacterial members growing at an optimal temperature of 80 degrees C and an optimal pH 8.1. The culture was able to utilize glucose, galactose, mannose, xylose, arabinose, maltose, sucrose, pyruvate and glycerol as carbon...

  14. A Hybrid P2P Overlay Network for Non-strictly Hierarchically Categorized Content

    Science.gov (United States)

    Wan, Yi; Asaka, Takuya; Takahashi, Tatsuro

    In P2P content distribution systems, there are many cases in which the content can be classified into hierarchically organized categories. In this paper, we propose a hybrid overlay network design suitable for such content called Pastry/NSHCC (Pastry for Non-Strictly Hierarchically Categorized Content). The semantic information of classification hierarchies of the content can be utilized regardless of whether they are in a strict tree structure or not. By doing so, the search scope can be restrained to any granularity, and the number of query messages also decreases while maintaining keyword searching availability. Through simulation, we showed that the proposed method provides better performance and lower overhead than unstructured overlays exploiting the same semantic information.

  15. Weak asymptotic solution for a non-strictly hyperbolic system of conservation laws-II

    Directory of Open Access Journals (Sweden)

    Manas Ranjan Sahoo

    2016-04-01

    Full Text Available In this article we introduce a concept of entropy weak asymptotic solution for a system of conservation laws and construct the same for a prolonged system of conservation laws which is highly non-strictly hyperbolic. This is first done for Riemann type initial data by introducing $\\delta,\\delta',\\delta''$ waves along a discontinuity curve and then for general initial data by piecing together the Riemann solutions.

  16. Multiple-Set Split Feasibility Problems for κ-Strictly Pseudononspreading Mapping in Hilbert Spaces

    Directory of Open Access Journals (Sweden)

    Jing Quan

    2013-01-01

    Full Text Available The purpose of this paper is to prove some weak and strong convergence theorems for solving the multiple-set split feasibility problems for κ-strictly pseudononspreading mapping in infinite-dimensional Hilbert spaces by using the proposed iterative method. The main results presented in this paper extend and improve the corresponding results of Xu et al. (2006, of Osilike et al. (2011, and of many other authors.

  17. Multiobjective Optimization for the Forecasting Models on the Base of the Strictly Binary Trees

    OpenAIRE

    Nadezhda Astakhova; Liliya Demidova; Evgeny Nikulchev

    2016-01-01

    The optimization problem dealing with the development of the forecasting models on the base of strictly binary trees has been considered. The aim of paper is the comparative analysis of two optimization variants which are applied for the development of the forecasting models. Herewith the first optimization variant assumes the application of one quality indicator of the forecasting model named as the affinity indicator and the second variant realizes the application of two quality indicators ...

  18. Cannabis legalization with strict regulation, the overall superior policy option for public health.

    Science.gov (United States)

    Rehm, J; Fischer, B

    2015-06-01

    Cannabis is the most prevalently used drug globally, with many jurisdictions considering varying reform options to current policies to deal with this substance and associated harm. Three policy options are available: prohibition, decriminalization, and legalization, with prohibition currently the dominant model globally. This contribution gives reasons why legalization with strict regulation should be considered superior to other options with respect to public health in high income countries in North America. © 2015 ASCPT.

  19. Examination of the PCICE method in the nearly incompressible, as well as strictly incompressible, limits

    International Nuclear Information System (INIS)

    Berry, Ray A.; Martineau, Richard C.

    2007-01-01

    The conservative-form, pressure-based PCICE numerical method (Martineau and Berry, 2004) (Berry, 2006), recently developed for computing transient fluid flows of all speeds from very low to very high (with strong shocks), is simplified and generalized. Though the method automatically treats a continuous transition of compressibility, three distinct, limiting compressibility regimes are formally defined for purposes of discussion and comparison with traditional methods - the strictly incompressible limit, the nearly incompressible limit, and the fully compressible limit. The PCICE method's behavior is examined in each limiting regime. In the strictly incompressible limit the PCICE algorithm reduces to the traditional MAC-type method with velocity divergence driving the pressure Poisson equation. In the nearly incompressible limit the PCICE algorithm is found to reduce to a generalization of traditional incompressible methods, i.e. to one in which not only the velocity divergence effect, but also the density gradient effect is included as a driving function in the pressure Poisson equation. This nearly incompressible regime has received little attention, and it appears that in the past, strictly incompressible methods may have been conveniently applied to flows in this regime at the expense of ignoring a potentially important coupling mechanism. This could be significant in many important flows; for example, in natural convection flows resulting from high heat flux. In the fully compressible limit or regime, the algorithm is found to reduce to an expression equivalent to density-based methods for high-speed flow. (author)

  20. Frequency effect on p-nitrophenol degradation under conditions of strict acoustic and electric control

    Directory of Open Access Journals (Sweden)

    Chang-ping Zhu

    2011-03-01

    Full Text Available The process of decomposing p-nitrophenol (PNP with power ultrasound requires strict control of acoustic and electric conditions. In this study, the conditions, including acoustic power and acoustic intensity, but not ultrasonic frequency, were controlled strictly at constant levels. The absorbency and the COD concentrations of the samples were measured in order to show the variation of the sample concentration. The results show significant differences in the trend of the solution degradation rate as acoustic power increases after the PNP solution (with a concentration of 114 mg/L and a pH value of 5.4 is irradiated for 60 min with ultrasonic frequencies of 530.8 kHz, 610.6 kHz, 855.0 kHz, and 1 130.0 kHz. The degradation rate of the solution increases with time and acoustic power (acoustic intensity. On the other hand, the degradation rate of the solution is distinctly dependent on frequency when the acoustic power and intensity are strictly controlled and maintained at constant levels. The degradation rate of the PNP solution declines with ultrasonic frequencies of 530.8 kHz, 610.6 kHz, 855.0 kHz, and 1 130.0 kHz; the COD concentration, on the contrary, increase.

  1. TESTING STRICT HYDROSTATIC EQUILIBRIUM IN SIMULATED CLUSTERS OF GALAXIES: IMPLICATIONS FOR A1689

    International Nuclear Information System (INIS)

    Molnar, S. M.; Umetsu, K.; Chiu, I.-N.; Chen, P.; Hearn, N.; Broadhurst, T.; Bryan, G.; Shang, C.

    2010-01-01

    Accurate mass determination of clusters of galaxies is crucial if they are to be used as cosmological probes. However, there are some discrepancies between cluster masses determined based on gravitational lensing and X-ray observations assuming strict hydrostatic equilibrium (i.e., the equilibrium gas pressure is provided entirely by thermal pressure). Cosmological simulations suggest that turbulent gas motions remaining from hierarchical structure formation may provide a significant contribution to the equilibrium pressure in clusters. We analyze a sample of massive clusters of galaxies drawn from high-resolution cosmological simulations and find a significant contribution (20%-45%) from non-thermal pressure near the center of relaxed clusters, and, in accord with previous studies, a minimum contribution at about 0.1 R vir , growing to about 30%-45% at the virial radius, R vir . Our results strongly suggest that relaxed clusters should have significant non-thermal support in their core region. As an example, we test the validity of strict hydrostatic equilibrium in the well-studied massive galaxy cluster A1689 using the latest high-resolution gravitational lensing and X-ray observations. We find a contribution of about 40% from non-thermal pressure within the core region of A1689, suggesting an alternate explanation for the mass discrepancy: the strict hydrostatic equilibrium is not valid in this region.

  2. Temporary Strict Maternal Avoidance of Cow’s Milk and Infantile Colic

    Directory of Open Access Journals (Sweden)

    Firoozeh Sajedi

    2009-12-01

    Full Text Available Infant colic is a common problem characterized by excessive crying and fussing. We examined whether colic symptoms of exclusively breast-milk-fed infants would be improved by temporary strict maternal avoidance of cows milk. This study is analytic and experimental. Sixty-six subjects were recruited during winter of 2006 from a clinic in Isfahan, Iran. Breast-milk-fed in-fants with "colic", age 3-6 months and to be in otherwise good health were referred by pediatri-cians. The intervention was 1 week period of strict maternal avoidance of cows milk while they continued exclusive breast-milk-feeding. All infants showed improvement in distressed behavior (crying and fussing during intervention. The total recorded crying and fussing time was reduced by an average of 31%. A significant difference was found in cry and fuss time between first and last 2 days of intervention (P = 0.000. Cows milk proteins may play an etiologic role in colic. We propose that a brief intervention with strict maternal avoidance of cows milk may be an effective treatment for colic in some breast-milk-fed infants.

  3. FTIR Calibration Methods and Issues

    Science.gov (United States)

    Perron, Gaetan

    Over the past 10 years, several space-borne FTIR missions were launched for atmospheric research, environmental monitoring and meteorology. One can think of the Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) launched by the European Space Agency, the Atmospheric Chemistry Experiment (ACE) launched by the Canadian Space Agency, the Tropospheric Emission Spectrometer (TES) launched by NASA and the Infrared Atmospheric Sounding Interferometer (IASI) launched by Eumetsat in Europe. Others are near to be launched, namely the Cross-track Infrared Sounder (CrIS) from the Integrated Program Of- fice in the United States and the Thermal And Near infrared Sensor for carbon Observation (TANSO) from the Japan Aerospace Exploration Agency. Moreover, several missions under definition foresee the use of this technology as sensor, e.g. Meteosat Third Generation (MTG), Eumetsat Polar System (EPS) and the Premier mission, one of the six candidates of the next ESA Earth Explorer Core Mission. In order to produce good quality products, calibration is essential. Calibrated data is the output of three main sub-systems that are tightly coupled: the instrument, the calibration targets and the level 1B processor. Calibration requirements must be carefully defined and propagated to each sub-system. Often, they are carried out by different parties which add to the complexity. Under budget and schedule pressure, some aspects are sometimes neglected and jeopardized final quality. For space-borne FTIR, level 1B outputs are spectra that are radiometrically, spectrally calibrated and geolocated. Radiometric calibration means to assign an intensity value in units to the y-axis. Spectral calibration means to assign to the x-axis the proper frequency value in units. Finally, geolocated means to assign a target position over the earth geoid i.e. longitude, latitude and altitude. This paper will present calibration methods and issues related to space-borne FTIR missions, e.g. two

  4. Rate Control Efficacy in Permanent Atrial Fibrillation : Successful and Failed Strict Rate Control Against a Background of Lenient Rate Control

    NARCIS (Netherlands)

    Groenveld, Hessel F.; Tijssen, Jan G. P.; Crijns, Harry J. G. M.; Van den Berg, Maarten P.; Hillege, Hans L.; Alings, Marco; Van Veldhuisen, Dirk J.; Van Gelder, Isabelle C.

    2013-01-01

    Objectives This study sought to investigate differences in outcome between patients treated with successful strict, failed strict, and lenient rate control. Background The RACE II (Rate Control Efficacy in Permanent Atrial Fibrillation) study showed no difference in outcome between lenient and

  5. Strict versus liberal insulin therapy in the cardiac surgery patient: An evidence-based practice development, implementation and evaluation project.

    Science.gov (United States)

    Gordon, Jacqueline M; Lauver, Lori S; Buck, Harleah G

    2018-02-01

    Hyperglycemia post-cardiac surgery is associated with poor clinical outcomes. Recent studies suggest maintaining liberal glycemic control (liberal CII protocol. Retrospective review of 144 strict CII patient records and 147 liberal CII patient records. Mean blood glucose was 159.8mg/dL (liberal CII) compared to 143.3mg/dL (strict CII) (p≤0.001). No surgical site infections occurred in either group. Mean ICU length of stay was 4.5days (liberal) versus 4.4days (strict) (p=0.74). Two 30-day mortalities occurred for the liberal cohort compared to no deaths in the strict group (p=0.49). Hypoglycemia incidence within 24h after surgery was 0.1% (liberal) compared to 0.3% (strict) compared to (p=0.16). Use of a nurse managed liberal CII resulted in similar outcomes with fewer incidents of hypoglycemia. Copyright © 2017. Published by Elsevier Inc.

  6. Effects of growth temperature and strictly anaerobic recovery on the survival of Listeria monocytogenes during pasteurization.

    Science.gov (United States)

    Knabel, S J; Walker, H W; Hartman, P A; Mendonca, A F

    1990-02-01

    Listeria monocytogenes F5069 was suspended in either Trypticase soy broth-0.6% yeast extract (TSBYE) or sterile, whole milk and heated at 62.8 degrees C in sealed thermal death time tubes. Severely heat-injured cells were recovered in TSBYE within sealed thermal death time tubes because of the formation of reduced conditions in the depths of the TSBYE. Also, the use of strictly anaerobic Hungate techniques significantly increased recovery in TSBYE containing 1.5% agar compared with aerobically incubated controls. The exogenous addition of catalase, but not superoxide dismutase, slightly increased the recovery of heat-injured cells in TSBYE containing 1.5% agar incubated aerobically. Growth of cells at 43 degrees C caused a greater increase in heat resistance as compared with cells heat shocked at 43 degrees C or cells grown at lower temperatures. Growth of L. monocytogenes at 43 degrees C and enumeration by the use of strictly anaerobic Hungate techniques resulted in D62.8 degrees C values that were at least sixfold greater than those previously obtained by using cells grown at 37 degrees C and aerobic plating. Results indicate that, under the conditions of the present study, high levels of L. monocytogenes would survive the minimum low-temperature, long-time treatment required by the U.S. Food and Drug Administration for pasteurizing milk. The possible survival of low levels of L. monocytogenes during high-temperature, short-time pasteurization and enumeration of injured cells by recovery on selective media under strictly anaerobic conditions are discussed.

  7. RelTime Rates Collapse to a Strict Clock When Estimating the Timeline of Animal Diversification.

    Science.gov (United States)

    Lozano-Fernandez, Jesus; Dos Reis, Mario; Donoghue, Philip C J; Pisani, Davide

    2017-05-01

    Establishing an accurate timescale for the history of life is crucial to understand evolutionary processes. For this purpose, relaxed molecular clock models implemented in a Bayesian MCMC framework are generally used. However, these methods are time consuming. RelTime, a non-Bayesian method implementing a fast, ad hoc, algorithm for relative dating, was developed to overcome the computational inefficiencies of Bayesian software. RelTime was recently used to investigate the timing of origin of animals, yielding results consistent with early strict clock studies from the 1980s and 1990s, estimating metazoans to have a Mesoproterozoic origin-over a billion years ago. RelTime results are unexpected and disagree with the largest majority of modern, relaxed, Bayesian molecular clock analyses, which suggest animals originated in the Tonian-Cryogenian (less that 850 million years ago). Here, we demonstrate that RelTime-inferred divergence times for the origin of animals are spurious, a consequence of the inability of RelTime to relax the clock along the internal branches of the animal phylogeny. RelTime-inferred divergence times are comparable to strict-clock estimates because they are essentially inferred under a strict clock. Our results warn us of the danger of using ad hoc algorithms making implicit assumptions about rate changes along a tree. Our study roundly rejects a Mesoproterozoic origin of animals; metazoans emerged in the Tonian-Cryogenian, and diversified in the Ediacaran, in the immediate prelude to the routine fossilization of animals in the Cambrian associated with the emergence of readily preserved skeletons. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  8. Effect of cryopreservation and lyophilization on viability and growth of strict anaerobic human gut microbes.

    Science.gov (United States)

    Bircher, Lea; Geirnaert, Annelies; Hammes, Frederik; Lacroix, Christophe; Schwab, Clarissa

    2018-04-17

    Strict anaerobic gut microbes have been suggested as 'next-generation probiotics' for treating several intestinal disorders. The development of preservation techniques is of major importance for therapeutic application. This study investigated cryopreservation (-80°C) and lyophilization survival and storage stability (4°C for 3 months) of the strict anaerobic gut microbes Bacteroides thetaiotaomicron, Faecalibacterium prausnitzii, Roseburia intestinalis, Anaerostipes caccae, Eubacterium hallii and Blautia obeum. To improve preservation survival, protectants sucrose and inulin (both 5% w/v) were added for lyophilization and were also combined with glycerol (15% v/v) for cryopreservation. Bacterial fitness, evaluated by maximum growth rate and lag phase, viability and membrane integrity were determined using a standardized growth assay and by flow cytometry as markers for preservation resistance. Lyophilization was more detrimental to viability and fitness than cryopreservation, but led to better storage stability. Adding sucrose and inulin enhanced viability and the proportion of intact cells during lyophilization of all strains. Viability of protectant-free B. thetaiotaomicron, A. caccae and F. prausnitzii was above 50% after cryopreservation and storage and increased to above 80% if protectants were present. The addition of glycerol, sucrose and inulin strongly enhanced the viability of B. obeum, E. hallii and R. intestinalis from 0.03-2% in protectant-free cultures to 11-37%. This is the first study that quantitatively compared the effect of cryopreservation and lyophilization and the addition of selected protectants on viability and fitness of six strict anaerobic gut microbes. Our results suggest that efficiency of protectants is process- and species-specific. © 2018 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology.

  9. Effects of growth temperature and strictly anaerobic recovery on the survival of Listeria monocytogenes during pasteurization.

    OpenAIRE

    Knabel, S J; Walker, H W; Hartman, P A; Mendonca, A F

    1990-01-01

    Listeria monocytogenes F5069 was suspended in either Trypticase soy broth-0.6% yeast extract (TSBYE) or sterile, whole milk and heated at 62.8 degrees C in sealed thermal death time tubes. Severely heat-injured cells were recovered in TSBYE within sealed thermal death time tubes because of the formation of reduced conditions in the depths of the TSBYE. Also, the use of strictly anaerobic Hungate techniques significantly increased recovery in TSBYE containing 1.5% agar compared with aerobicall...

  10. The Dirichlet problem for the Monge-Ampere equation in convex (but not strictly convex domains

    Directory of Open Access Journals (Sweden)

    David Hartenstine

    2006-10-01

    Full Text Available It is well-known that the Dirichlet problem for the Monge-Amp`ere equation $det D^2 u = mu$ in a bounded strictly convex domain $Omega$ in $mathbb{R}^n$ has a weak solution (in the sense of Aleksandrov for any finite Borel measure $mu$ on $Omega$ and for any continuous boundary data. We consider the Dirichlet problem when $Omega$ is only assumed to be convex, and give a necessary and sufficient condition on the boundary data for solvability.

  11. Selections of the metric projection operator and strict solarity of sets with continuous metric projection

    Science.gov (United States)

    Alimov, A. R.

    2017-07-01

    In a broad class of finite-dimensional Banach spaces, we show that a closed set with lower semicontinuous metric projection is a strict sun, admits a continuous selection of the metric projection operator onto it, has contractible intersections with balls, and its (nonempty) intersection with any closed ball is a retract of this ball. For sets with continuous metric projection, a number of new results relating the solarity of such sets to the stability of the operator of best approximation are obtained. Bibliography 25 titles.

  12. Transplanting Diseases from Organ Donors in Western Europe: Fault Liability or Strict Liability?

    Science.gov (United States)

    Broeckx, Nils; Verhoeven, Dimitri

    2015-06-01

    This article will examine the problem of disease transmission through organ transplantation from a civil liability perspective. Both fault liability and strict product liability might be possible. These two types of liability will be compared, while applying them to the actions of the central parties involved in organ donation and transplantation, namely the physician/hospital, the donor and the organ exchange organisation. While product liability is generally an easier way to obtain compensation than fault liability, it might nevertheless place too heavy a burden on the transplant professionals.

  13. Single molecule experiments challenge the strict wave-particle dualism of light.

    Science.gov (United States)

    Greulich, Karl Otto

    2010-01-21

    Single molecule techniques improve our understanding of the photon and light. If the single photon double slit experiment is performed at the "single photon limit" of a multi-atom light source, faint light pulses with more than one photon hamper the interpretation. Single molecules, quantum dots or defect centres in crystals should be used as light source. "Single photon detectors" do not meet their promise-only "photon number resolving single photon detectors" do so. Particularly, the accumulation time argument, the only safe basis for the postulate of a strictly particle like photon, has so far not yet been verified.

  14. Single Molecule Experiments Challenge the Strict Wave-Particle Dualism of Light

    Directory of Open Access Journals (Sweden)

    Karl Otto Greulich

    2010-01-01

    Full Text Available Single molecule techniques improve our understanding of the photon and light. If the single photon double slit experiment is performed at the “single photon limit” of a multi-atom light source, faint light pulses with more than one photon hamper the interpretation. Single molecules, quantum dots or defect centres in crystals should be used as light source. “Single photon detectors” do not meet their promise―only “photon number resolving single photon detectors” do so. Particularly, the accumulation time argument, the only safe basis for the postulate of a strictly particle like photon, has so far not yet been verified.

  15. Fuzzy Adaptive Decentralized Optimal Control for Strict Feedback Nonlinear Large-Scale Systems.

    Science.gov (United States)

    Sun, Kangkang; Sui, Shuai; Tong, Shaocheng

    2018-04-01

    This paper considers the optimal decentralized fuzzy adaptive control design problem for a class of interconnected large-scale nonlinear systems in strict feedback form and with unknown nonlinear functions. The fuzzy logic systems are introduced to learn the unknown dynamics and cost functions, respectively, and a state estimator is developed. By applying the state estimator and the backstepping recursive design algorithm, a decentralized feedforward controller is established. By using the backstepping decentralized feedforward control scheme, the considered interconnected large-scale nonlinear system in strict feedback form is changed into an equivalent affine large-scale nonlinear system. Subsequently, an optimal decentralized fuzzy adaptive control scheme is constructed. The whole optimal decentralized fuzzy adaptive controller is composed of a decentralized feedforward control and an optimal decentralized control. It is proved that the developed optimal decentralized controller can ensure that all the variables of the control system are uniformly ultimately bounded, and the cost functions are the smallest. Two simulation examples are provided to illustrate the validity of the developed optimal decentralized fuzzy adaptive control scheme.

  16. Study on Environment Performance Evaluation and Regional Differences of Strictly-Environmental-Monitored Cities in China

    Directory of Open Access Journals (Sweden)

    Ji Guo

    2017-12-01

    Full Text Available With the rapid economic growth and development, the problem of environmental pollution in China’s cities is becoming increasingly serious, and environmental pollution takes on a regional difference. There is, however, little comprehensive evaluation on the environmental performance and the regional difference of strictly-environmental-monitored cities in China. In this paper, the environmental performance of 109 strictly-environmental-monitored cities in China is evaluated in terms of natural performance, management performance, and scale performance by Data Envelopment Analysis (DEA, incorporating PM2.5 and PM10 as undesirable outputs. The empirical results show that: (1 At present, the natural performance is quite high, while the management performance is noticeably low for most cities. (2 The gap between the level of economic development and environmental protection among cities in China is large, and the scale efficiency of big cities is better than that of smaller cities. The efficiency value of large-scale cities such as Beijing, Shanghai, Guangzhou, Shenzhen, etc. is high, equaling 1; the value of smaller cities such as Sanmenxia, Baoding, Mudanjiang, and Pingdingshan is low, close to 0, indicating that big cities are characterized by high environmental efficiency. (3 From the perspective of region, the level of environmental performance in China is very uneven. For example, the environmental efficiency level of the Pan-Pearl River Delta region is superior to that of the Pan-Yangtze River region and the Bahia Rim region, whose values of environmental efficiency are 0.858, 0.658, and 0.622 respectively. The average efficiency of the Southern Coastal Economic Zone, Eastern Coastal Comprehensive Economic Zone, and the Comprehensive Economic Zone in the middle reaches of the Yangtze River is higher than that of other regions. Finally, corresponding countermeasures and suggestions are put forward. The method used in this paper is applicable

  17. Disordered strictly jammed binary sphere packings attain an anomalously large range of densities

    Science.gov (United States)

    Hopkins, Adam B.; Stillinger, Frank H.; Torquato, Salvatore

    2013-08-01

    Previous attempts to simulate disordered binary sphere packings have been limited in producing mechanically stable, isostatic packings across a broad spectrum of packing fractions. Here we report that disordered strictly jammed binary packings (packings that remain mechanically stable under general shear deformations and compressions) can be produced with an anomalously large range of average packing fractions 0.634≤ϕ≤0.829 for small to large sphere radius ratios α restricted to α≥0.100. Surprisingly, this range of average packing fractions is obtained for packings containing a subset of spheres (called the backbone) that are exactly strictly jammed, exactly isostatic, and also generated from random initial conditions. Additionally, the average packing fractions of these packings at certain α and small sphere relative number concentrations x approach those of the corresponding densest known ordered packings. These findings suggest for entropic reasons that these high-density disordered packings should be good glass formers and that they may be easy to prepare experimentally. We also identify an unusual feature of the packing fraction of jammed backbones (packings with rattlers excluded). The backbone packing fraction is about 0.624 over the majority of the α-x plane, even when large numbers of small spheres are present in the backbone. Over the (relatively small) area of the α-x plane where the backbone is not roughly constant, we find that backbone packing fractions range from about 0.606 to 0.829, with the volume of rattler spheres comprising between 1.6% and 26.9% of total sphere volume. To generate isostatic strictly jammed packings, we use an implementation of the Torquato-Jiao sequential linear programming algorithm [Phys. Rev. EPLEEE81539-375510.1103/PhysRevE.82.061302 82, 061302 (2010)], which is an efficient producer of inherent structures (mechanically stable configurations at the local maxima in the density landscape). The identification and

  18. Disordered strictly jammed binary sphere packings attain an anomalously large range of densities.

    Science.gov (United States)

    Hopkins, Adam B; Stillinger, Frank H; Torquato, Salvatore

    2013-08-01

    Previous attempts to simulate disordered binary sphere packings have been limited in producing mechanically stable, isostatic packings across a broad spectrum of packing fractions. Here we report that disordered strictly jammed binary packings (packings that remain mechanically stable under general shear deformations and compressions) can be produced with an anomalously large range of average packing fractions 0.634≤φ≤0.829 for small to large sphere radius ratios α restricted to α≥0.100. Surprisingly, this range of average packing fractions is obtained for packings containing a subset of spheres (called the backbone) that are exactly strictly jammed, exactly isostatic, and also generated from random initial conditions. Additionally, the average packing fractions of these packings at certain α and small sphere relative number concentrations x approach those of the corresponding densest known ordered packings. These findings suggest for entropic reasons that these high-density disordered packings should be good glass formers and that they may be easy to prepare experimentally. We also identify an unusual feature of the packing fraction of jammed backbones (packings with rattlers excluded). The backbone packing fraction is about 0.624 over the majority of the α-x plane, even when large numbers of small spheres are present in the backbone. Over the (relatively small) area of the α-x plane where the backbone is not roughly constant, we find that backbone packing fractions range from about 0.606 to 0.829, with the volume of rattler spheres comprising between 1.6% and 26.9% of total sphere volume. To generate isostatic strictly jammed packings, we use an implementation of the Torquato-Jiao sequential linear programming algorithm [Phys. Rev. E 82, 061302 (2010)], which is an efficient producer of inherent structures (mechanically stable configurations at the local maxima in the density landscape). The identification and explicit construction of binary packings

  19. Lyme Neuroborreliosis: Preliminary Results from an Urban Referral Center Employing Strict CDC Criteria for Case Selection

    Directory of Open Access Journals (Sweden)

    David S. Younger

    2010-01-01

    Full Text Available Lyme neuroborreliosis or “neurological Lyme disease” was evidenced in 2 of 23 patients submitted to strict criteria for case selection of the Centers for Disease Control and Prevention employing a two-tier test to detect antibodies to Borrelia burgdorferi at a single institution. One patient had symptomatic polyradiculoneuritis, dysautonomia, and serological evidence of early infection; and another had symptomatic small fiber sensory neuropathy, distal polyneuropathy, dysautonomia, and serological evidence of late infection. In the remaining patients symptoms initially ascribed to Lyme disease were probably unrelated to B. burgdorferi infection. Our findings suggest early susceptibility and protracted involvement of the nervous system most likely due to the immunological effects of B. burgdorferi infection, although the exact mechanisms remain uncertain.

  20. On The Integral Representation of Strictly Continuous Set-Valued Maps

    Directory of Open Access Journals (Sweden)

    Anaté K. Lakmon

    2015-11-01

    Full Text Available Let T be a completely regular topological space and C(T be the space of bounded, continuous real-valued functions on T. C(T is endowed with the strict topology (the topology generated by seminorms determined by continuous functions vanishing at in_nity. R. Giles ([13], p. 472, Theorem 4.6 proved in 1971 that the dual of C(T can be identi_ed with the space of regular Borel measures on T. We prove this result for positive, additive set-valued maps with values in the space of convex weakly compact non-empty subsets of a Banach space and we deduce from this result the theorem of R. Giles ([13], theorem 4.6, p.473.

  1. A Total Variation Model Based on the Strictly Convex Modification for Image Denoising

    Directory of Open Access Journals (Sweden)

    Boying Wu

    2014-01-01

    Full Text Available We propose a strictly convex functional in which the regular term consists of the total variation term and an adaptive logarithm based convex modification term. We prove the existence and uniqueness of the minimizer for the proposed variational problem. The existence, uniqueness, and long-time behavior of the solution of the associated evolution system is also established. Finally, we present experimental results to illustrate the effectiveness of the model in noise reduction, and a comparison is made in relation to the more classical methods of the traditional total variation (TV, the Perona-Malik (PM, and the more recent D-α-PM method. Additional distinction from the other methods is that the parameters, for manual manipulation, in the proposed algorithm are reduced to basically only one.

  2. Residual diffeomorphisms and symplectic soft hairs: The need to refine strict statement of equivalence principle

    Science.gov (United States)

    Sheikh-Jabbari, M. M.

    2016-09-01

    General covariance is the cornerstone of Einstein’s general relativity (GR) and implies that any two metrics related by diffeomorphisms are physically equivalent. There are, however, many examples pointing to the fact that this strict statement of general covariance needs refinement. There are a very special (measure-zero) subset of diffeomorphisms, the residual diffeomorphisms, to which one can associate well-defined conserved charges. This would hence render these diffeomorphic geometries physically distinct. We discuss that these symmetries may be appropriately called “symplectic symmetries”. Existence of residual diffeomorphisms and symplectic symmetries can be a quite general feature and not limited to the examples discussed so far in the literature. We propose that, in the context of black holes, these diffeomorphic, but distinct, geometries may be viewed as “symplectic soft hair” on black holes. We comment on how this may remedy black hole microstate problem, which in this context are dubbed as “horizon fluffs”.

  3. Reactions to terror attacks in ultra-orthodox jews: the cost of maintaining strict identity.

    Science.gov (United States)

    Ankri, Yael L E; Bachar, Eytan; Shalev, Arieh Y

    2010-01-01

    Traumatic events can shatter faith and beliefs. The responses of Ultra-Orthodox survivors of deadly terrorist attacks illustrate an effort to reconcile dreadful experiences with deeply embedded beliefs. Qualified clinicians prospectively evaluated self-reported and interviewer-generated posttraumatic stress disorder (PTSD) symptoms and cognitive appraisal in Ultra-Orthodox (n = 20) and non-Ultra-Orthodox (n = 33) survivors of suicide bus-bombing incidents in Jerusalem. Ultra-Orthodox survivors reported higher levels of PTSD symptoms and more personal guilt. Their narratives reflected an unshaken belief in Just Providence, within which being a victim of terror was perceived as a Just retribution for known or unknown wrongdoing. Survivors' reactions to trauma often reflect an effort to reconcile incongruous experiences with previously held beliefs. When treating strict believers, helpers should be sensitive to the identity-preserving function of posttraumatic cognitions.

  4. On a class of adjustable rate mortgage loans subject to a strict balance principle

    DEFF Research Database (Denmark)

    Astrup Jensen, Bjarne

    We describe the background and the basic funding mechanisms for the type of adjustable rate mortgageloans that were introduced in the Danish market in 1996. Each loan is funded separately by tap issuingpass-through mortgage bonds (`strict balance principle'). The novelty is a funding mechanism...... that usesa roll-over strategy, where long term loans are funded by sequentially issuing short term pass-throughbonds, and the first issuer of these loans obtained a patent on the funding principles in 1999. Publiclyavailable descriptions of the principles leave an impression of very complicated numerical...... algorithms.The algorithms described here show that the essentials can be reduced to a `back of an envelope' complexity.Keywords: Adjustable rate mortgages, balance principle, patent, yield curve riding...

  5. Strict Liability Versus Policy and Regulation for Environmental Protection and Agricultural Waste Management in Malaysia

    Directory of Open Access Journals (Sweden)

    Mohd Bakri Ishak

    2010-01-01

    Full Text Available Basically, strict liability is part of the mechanism for expressing judgment or sentence by using direct evidence. This principle is very useful in order to obtain remedies from any damage either directly or indirectly. The principle in Rylands v Fletcher is responsible on imposing strict liability where if something brought onto land or collected there escapes liability under this rule can include not only the owner of land but also those who control or occupation on it. However, as a matter of fact, policy and regulation are also important in taking any action against any party who are responsible for environmental pollution or damage, which may include mismanagement of waste or industrial waste or agricultural waste. There are certain policies and regulations on environmental protection such as the National Environmental Policy, certain Acts and several regulations under the Environmental Quality Act 1974 (Act 127, which are very useful for agricultural waste management inter alia: Waters Act 1920 (Act 418, Environmental Quality (Prescribed Premises (Crude Palm Oil Regulations 1977, Environmental Quality (Prescribed Premises (Raw Natural Rubber Regulations 1978, Environmental Quality (Sewage and Industrial Effluents Regulations 1979, and Environmental Quality (Compounding of Offences Rules 1978. As a matter of fact, we should realize that time is of an essence for any parties which are involved in court cases and especially in avoiding the element of externality, which is commonly suffered by the government. In making this paper, therefore, some element of comparison with certain developed jurisdiction such as in the United Kingdom and Japan could not be avoided in order to obtain better outcome and to be more practical for the purpose of environmental protection and agricultural waste management.

  6. The Effect of Strict Segregation on Pseudomonas aeruginosa in Cystic Fibrosis Patients.

    Directory of Open Access Journals (Sweden)

    Rosa van Mansfeld

    Full Text Available Segregation of patients with cystic fibrosis (CF was implemented to prevent chronic infection with epidemic Pseudomonas aeruginosa strains with presumed detrimental clinical effects, but its effectiveness has not been carefully evaluated.The effect of strict segregation on the incidence of P. aeruginosa infection in CF patients was investigated through longitudinal protocolized follow-up of respiratory tract infection before and after segregation. In two nested cross-sectional studies in 2007 and 2011 the P. aeruginosa population structure was investigated and clinical parameters were determined in patients with and without infection with the Dutch epidemic P. aeruginosa clone (ST406.Of 784 included patients 315 and 382 were at risk for acquiring chronic P. aeruginosa infection before and after segregation. Acquisition rates were, respectively, 0.14 and 0.05 per 1,000 days at risk (HR: 0.66, 95% CI [0.2548-1.541]; p = 0.28. An exploratory subgroup analysis indicated lower acquisition after segregation in children < 15 years of age (HR: 0.43, 95% CI[0.21-0.95]; p = 0.04. P. aeruginosa population structure did not change after segregation and ST406 was not associated with lung function decline, death or lung transplantation.Strict segregation was not associated with a statistically significant lower acquisition of chronic P. aeruginosa infection and ST406 was not associated with adverse clinical outcome. After segregation there were no new acquisitions of ST406. In an unplanned exploratory analysis chronic acquisition of P. aeruginosa was lower after implementation of segregation in patients under 15 years of age.

  7. Weight of fitness deviation governs strict physical chaos in replicator dynamics

    Science.gov (United States)

    Pandit, Varun; Mukhopadhyay, Archan; Chakraborty, Sagar

    2018-03-01

    Replicator equation—a paradigm equation in evolutionary game dynamics—mathematizes the frequency dependent selection of competing strategies vying to enhance their fitness (quantified by the average payoffs) with respect to the average fitnesses of the evolving population under consideration. In this paper, we deal with two discrete versions of the replicator equation employed to study evolution in a population where any two players' interaction is modelled by a two-strategy symmetric normal-form game. There are twelve distinct classes of such games, each typified by a particular ordinal relationship among the elements of the corresponding payoff matrix. Here, we find the sufficient conditions for the existence of asymptotic solutions of the replicator equations such that the solutions—fixed points, periodic orbits, and chaotic trajectories—are all strictly physical, meaning that the frequency of any strategy lies inside the closed interval zero to one at all times. Thus, we elaborate on which of the twelve types of games are capable of showing meaningful physical solutions and for which of the two types of replicator equation. Subsequently, we introduce the concept of the weight of fitness deviation that is the scaling factor in a positive affine transformation connecting two payoff matrices such that the corresponding one-shot games have exactly same Nash equilibria and evolutionary stable states. The weight also quantifies how much the excess of fitness of a strategy over the average fitness of the population affects the per capita change in the frequency of the strategy. Intriguingly, the weight's variation is capable of making the Nash equilibria and the evolutionary stable states, useless by introducing strict physical chaos in the replicator dynamics based on the normal-form game.

  8. Selvester scoring in patients with strict LBBB using the QUARESS software.

    Science.gov (United States)

    Xia, Xiaojuan; Chaudhry, Uzma; Wieslander, Björn; Borgquist, Rasmus; Wagner, Galen S; Strauss, David G; Platonov, Pyotr; Ugander, Martin; Couderc, Jean-Philippe

    2015-01-01

    Estimation of the infarct size from body-surface ECGs in post-myocardial infarction patients has become possible using the Selvester scoring method. Automation of this scoring has been proposed in order to speed-up the measurement of the score and improving the inter-observer variability in computing a score that requires strong expertise in electrocardiography. In this work, we evaluated the quality of the QuAReSS software for delivering correct Selvester scoring in a set of standard 12-lead ECGs. Standard 12-lead ECGs were recorded in 105 post-MI patients prescribed implantation of an implantable cardiodefibrillator (ICD). Amongst the 105 patients with standard clinical left bundle branch block (LBBB) patterns, 67 had a LBBB pattern meeting the strict criteria. The QuAReSS software was applied to these 67 tracings by two independent groups of cardiologists (from a clinical group and an ECG core laboratory) to measure the Selvester score semi-automatically. Using various level of agreement metrics, we compared the scores between groups and when automatically measured by the software. The average of the absolute difference in Selvester scores measured by the two independent groups was 1.4±1.5 score points, whereas the difference between automatic method and the two manual adjudications were 1.2±1.2 and 1.3±1.2 points. Eighty-two percent score agreement was observed between the two independent measurements when the difference of score was within two point ranges, while 90% and 84% score agreements were reached using the automatic method compared to the two manual adjudications. The study confirms that the QuAReSS software provides valid measurements of the Selvester score in patients with strict LBBB with minimal correction from cardiologists. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Strict stoichiometric homeostasis of Cryptomonas pyrenoidifera (Cryptophyceae in relation to N:P supply ratios

    Directory of Open Access Journals (Sweden)

    Eloísa Ramos Rodríguez

    2016-11-01

    Full Text Available A common freshwater cryptophyte, Cryptomonas pyrenoidifera, was cultivated in batch-cultures to analyze intraspecific variation in elemental stoichiometry along a broad gradient of pulsed phosphorus (P enrichment during the early acclimation period and to determine the immediate homeostatic capacity of the nitrogen-to-phosphorus (N:P ratio of this alga when nutrients are at saturating levels. Experimental results revealed that nitrogen (N and P cell quotas significantly increased with increasing P concentration. However, despite the wide range of N:P ratios in the medium, Cryptomonas N:P ratios were highly stable at higher P-level treatments, indicating a highly conservative behavior and suggesting strict elemental homeostasis when nutrients are at saturating levels. The strictly homeostatic N:P ratio appears to be attributable to their high potential for a fast luxury consumption of both N and P after a brief and intense episode of increased resource availability and to physiological limits on their nutrient storage capacity. Most importantly, the N:P biomass ratio at nutrient saturating levels converged around 11:1, which was the observed ratio of maximum internal cell quotas for N and P (i.e. Qmax,N:Qmax,P under the prevailing experimental conditions. This value is particularly informative for C. pyrenoidifera because it represents cell storage quotients and may be a taxon-specific evolutionary optimum, providing a reference point to infer the grade of nutrient-limitation. The experimental data give ranges of variation in C. pyrenoidifera elemental composition permitting, among others, proper parameterization of cryptophyte stoichiometry models.

  10. Strict follow-up programme including CT and (18) F-FDG-PET after curative surgery for colorectal cancer

    DEFF Research Database (Denmark)

    Sørensen, N F; Jensen, A B; Wille-Jørgensen, P

    2010-01-01

    Aim  The risk of local recurrence following curative surgery for colorectal cancer (CRC) is up to 50%. A rigorous follow-up program may increase survival. Guidelines on suitable methods for scheduled follow up examinations are needed. This study evaluates a strict follow-up program including...... supported a strict follow-up program following curative surgery for colorectal cancer. FDG-PET combined with CT should be included in control programs....

  11. Distributed generation: definition, benefits and issues

    OpenAIRE

    Guido Pepermans; Johan Driesen; Dries Haeseldonckx

    2003-01-01

    This paper starts from the observation that there is a renewed interest in small-scale electricity generation. The authors start with a survey of existing small-scale generation technologies and then move on with a discussion of the major benefits and issues of small-scale electricity generation. Different technologies are evaluated in terms of their possible contribution to the listed benefits and issues. Small-scale generation is also commonly called distributed generation, embedded generat...

  12. Immediate effect of instrumentation on the subgingival microflora in deep inflamed pockets under strict plaque control.

    Science.gov (United States)

    Rhemrev, G E; Timmerman, M F; Veldkamp, I; Van Winkelhoff, A J; Van der Velden, U

    2006-01-01

    To investigate (1) reduction in the number of microorganisms obtained directly after subgingival instrumentation, (2) rate of bacterial re-colonization during 2 weeks, under supragingival plaque-free conditions. Effects of subgingival instrumentation were measured at one deep pocket in 22 patients (11 smokers and 11 non-smokers). Immediately after initial therapy, experimental sites, under strict plaque control, were instrumented subgingivally. Microbiological evaluation was performed at pre-instrumentation, immediate post-instrumentation and 1 and 2 weeks post-instrumentation. Mean total anaerobic colony forming units (CFUs) dropped from 3.9 x 10(6) before to 0.09 x 10(6) immediately following instrumentation. Significant reductions were found for Tannerella forsythia, Micromonas micros, Fusobacterium nucleatum and spirochetes. Significant reductions were not observed for Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia and Campylobacter rectus. Except for spirochetes, no reduction in prevalence of specific periodontal bacteria was found immediately after instrumentation. During follow-up, mean total CFU tended to increase. Prevalence of periodontal bacteria further reduced. No effect of smoking was found. Results indicate that subgingival mechanical cleaning in itself, has a limited effect, in actually removing bacteria. The subsequent reduction in prevalence of specific periodontal bacteria shows that it is apparently difficult for these species to survive in treated pockets.

  13. Magnetic resonance imaging quantitation of changes in muscle volume during 7 days of strict bed rest.

    Science.gov (United States)

    Ferrando, A A; Stuart, C A; Brunder, D G; Hillman, G R

    1995-10-01

    Prolonged bed rest results in a loss of leg lean body mass. Previous studies using bed rest as a model for microgravity have shown decreases in leg mass after 12 and 14 d, 5 and 17 wk. As magnetic resonance imaging (MRI) can provide a precise and non-invasive means of determining muscle volume, we sought to determine if changes in leg muscle volume could be detected in bed rest periods as short as 7 d. Five young, healthy, male volunteers were subjected to 7 d of absolute bed rest. Each subject underwent MRI quantitation of segmental muscle volumes of the calves and thighs before and after bed rest. Eleven (calf) and nine (thigh) contiguous 1-cm thick transaxial images were generated over prescribed regions using a Technicare MRI imager with a 0.6T superconducting magnet and body coil. Image processing was performed using a generalized 8-bit medical image analysis package developed at University of Texas Medical Branch. Images were analyzed for muscle and non-muscle volumes (including fat, blood vessel, and bone marrow volumes). The MRI quantitation demonstrated bed rest-induced significant decreases in segmental thigh muscle (approximately 3.0%, p image analysis of MRI images provides a sensitive tool capable of detecting leg volume changes of as little as 3.0% over a 7-d period of strict bed rest.

  14. Managing curriculum transformation within strict university governance structures: an example from Damascus University Medical School.

    Science.gov (United States)

    Kayyal, Mohammad; Gibbs, Trevor

    2012-01-01

    As the world of medical education moves forward, it becomes increasingly clear that the transformative process is not as easy a process for all. Across the globe, there appears to be many barriers that obstruct or threaten innovation and change, most of which cause almost insurmountable problems to many schools. If transformative education is to result in an equitable raising of standards across such an unlevel playing field, schools have to find ways in overcoming these barriers. One seemingly common barrier to development occurs when medical schools are trapped within strict University governance structures; rules and regulations which are frequently inappropriate and obstructive to the transformation that must occur in today's medical educational paradigm. The Faculty of Medicine at Damascus University, one of the oldest and foremost medical schools in the Middle East, is one such school where rigid rules and regulations and traditional values are obstructing transformative change. This paper describes the problems, which the authors believe to be common to many, and explores how attempts have been made to overcome them and move the school into the twenty-first century. It is the ultimate purpose of this paper to raise awareness of the issue, share the lessons learned in order to assist others who are experiencing similar problems and possibly create opportunities for dialogue between schools.

  15. On a holomorphic Lefschetz formula in strictly pseudoconvex subdomains of complex manifolds

    International Nuclear Information System (INIS)

    Kytmanov, A M; Myslivets, S G; Tarkhanov, N N

    2004-01-01

    The classical Lefschetz formula expresses the number of fixed points of a continuous map f:M→M in terms of the transformation induced by f on the cohomology of M. In 1966, Atiyah and Bott extended this formula to elliptic complexes over a compact closed manifold. In particular, they obtained a holomorphic Lefschetz formula on compact complex manifolds without boundary. Brenner and Shubin (1981, 1991) extended the Atiyah-Bott theory to compact manifolds with boundary. On compact complex manifolds with boundary the Dolbeault complex is not elliptic, therefore the Atiyah-Bott theory is not applicable. Bypassing difficulties related to the boundary behaviour of Dolbeault cohomology, Donnelly and Fefferman (1986) obtained a formula for the number of fixed points in terms of the Bergman metric. The aim of this paper is to obtain a Lefschetz formula on relatively compact strictly pseudoconvex subdomains of complex manifolds X with smooth boundary, that is, to find the total Lefschetz number for a holomorphic endomorphism f * of the Dolbeault complex and to express it in terms of local invariants of the fixed points of f.

  16. Divergent changes in serum sterols during a strict uncooked vegan diet in patients with rheumatoid arthritis.

    Science.gov (United States)

    Agren, J J; Tvrzicka, E; Nenonen, M T; Helve, T; Hänninen, O

    2001-02-01

    The effects of a strict uncooked vegan diet on serum lipid and sterol concentrations were studied in patients with rheumatoid arthritis. The subjects were randomized into a vegan diet group (n 16), who consumed a vegan diet for 2-3 months, or into a control group (n 13), who continued their usual omnivorous diets. Serum total and LDL-cholesterol and -phospholipid concentrations were significantly decreased by the vegan diet. The levels of serum cholestanol and lathosterol also decreased, but serum cholestanol:total cholesterol and lathosterol:total cholesterol did not change. The effect of a vegan diet on serum plant sterols was divergent as the concentration of campesterol decreased while that of sitosterol increased. This effect resulted in a significantly greater sitosterol:campesterol value in the vegan diet group than in the control group (1.48 (SD 0.39) v. 0.72 (SD 0.14); P vegan diet changes the relative absorption rates of these sterols and/or their biliary clearance.

  17. Model-Based Adaptive Event-Triggered Control of Strict-Feedback Nonlinear Systems.

    Science.gov (United States)

    Li, Yuan-Xin; Yang, Guang-Hong

    2018-04-01

    This paper is concerned with the adaptive event-triggered control problem of nonlinear continuous-time systems in strict-feedback form. By using the event-sampled neural network (NN) to approximate the unknown nonlinear function, an adaptive model and an associated event-triggered controller are designed by exploiting the backstepping method. In the proposed method, the feedback signals and the NN weights are aperiodically updated only when the event-triggered condition is violated. A positive lower bound on the minimum intersample time is guaranteed to avoid accumulation point. The closed-loop stability of the resulting nonlinear impulsive dynamical system is rigorously proved via Lyapunov analysis under an adaptive event sampling condition. In comparing with the traditional adaptive backstepping design with a fixed sample period, the event-triggered method samples the state and updates the NN weights only when it is necessary. Therefore, the number of transmissions can be significantly reduced. Finally, two simulation examples are presented to show the effectiveness of the proposed control method.

  18. DNA remodelling by Strict Partial Endoreplication in orchids, an original process in the plant kingdom.

    Science.gov (United States)

    Brown, Spencer C; Bourge, Mickaël; Maunoury, Nicolas; Wong, Maurice; Bianchi, Michele Wolfe; Lepers-Andrzejewski, Sandra; Besse, Pascale; Siljak-Yakovlev, Sonja; Dron, Michel; Satiat-Jeunemaître, Béatrice

    2017-04-13

    DNA remodelling during endoreplication appears to be a strong developmental characteristic in orchids. In this study, we analysed DNA content and nuclei in 41 species of orchids to further map the genome evolution in this plant family. We demonstrate that the DNA remodelling observed in 36 out of 41 orchids studied corresponds to strict partial endoreplication. Such process is developmentally regulated in each wild species studied. Cytometry data analyses allowed us to propose a model where nuclear states 2C, 4E, 8E, etc. form a series comprising a fixed proportion, the euploid genome 2C, plus 2 to 32 additional copies of a complementary part of the genome. The fixed proportion ranged from 89% of the genome in Vanilla mexicana down to 19% in V. pompona, the lowest value for all 148 orchids reported. Insterspecific hybridisation did not suppress this phenomenon. Interestingly, this process was not observed in mass-produced epiphytes. Nucleolar volumes grow with the number of endocopies present, coherent with high transcription activity in endoreplicated nuclei. Our analyses suggest species-specific chromatin rearrangement. Towards understanding endoreplication, V. planifolia constitutes a tractable system for isolating the genomic sequences that confer an advantage via endoreplication from those that apparently suffice at diploid level. © The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  19. Strictly hyperbolic models of co-current three-phase flow withgravity

    Energy Technology Data Exchange (ETDEWEB)

    Juanes, Ruben; Patzek, Tadeusz W.

    2002-11-18

    We study the character of the equations in the traditional formulation of one-dimensional immiscible three-phase flow with gravity, in the limit of negligible capillarity. We restrict our analysis to co-current flow required for a displacement process; in cases of mixed co-current and counter-current flow, capillarity effects cannot be dropped from the formulation. The model makes use of the classical multiphase extension of Darcy's equation. It is well known that, if relative permeabilities are taken as fixed functions of saturations, the model yields regions in the saturation space where the system of equations is locally elliptic. We regard elliptic behavior as a nonphysical artifact of an incomplete formulation, and derive conditions on the relative permeabilities that ensure strict hyperbolicity of the governing equations. The key point is to acknowledge that a Darcy-type formulation is insufficient to capture all the physics of three-phase flow and that, consequently, the relative permeabilities are functionals that depend on the fluid viscosity ratio and the gravity number. The derived conditions are consistent with the type of displacements that take place in porous media. By means of an illustrative example, we show how elliptic behavior can be removed, even when using simplistic relative permeability models.

  20. Clinical impact of strict criteria for selectivity and lateralization in adrenal vein sampling.

    Science.gov (United States)

    Gasparetto, Alessandro; Angle, John F; Darvishi, Pasha; Freeman, Colbey W; Norby, Ray G; Carey, Robert M

    2015-04-01

    Selectivity index (SI) and lateralization index (LI) thresholds determine the adequacy of adrenal vein sampling (AVS) and the degree of lateralization. The purpose of this study was investigate the clinical outcome of patients whose adrenal vein sampling was interpreted using "strict criteria" (SC) (SIpre-stimuli≥3, SIpost-stimuli≥5 and LIpre-stimuli≥4, LIpost-stimuli≥4). A retrospective review of 73 consecutive AVS procedures was performed and 67 were technically successful. Forty-three patients showed lateralization and underwent surgery, while 24 did not lateralize and were managed conservatively. Systolic blood pressure (SBP), diastolic blood pressure (DBP), kalemia (K(+)), and the change in number of blood pressure (BP) medications were recorded for each patient before and after AVS and potential surgery were performed. In the surgery group, BP and K(+) changed respectively from 160±5.3/100±2.0 mmHg to 127±3.3/80±1.9 (p blood pressure medications were six (14.0%) in the lateralized group and 22 (91.7%) in the non-lateralized group (p <0.001). AVS interpretation with SC leads to significant clinical improvement in both patients who underwent surgery and those managed conservatively.

  1. Generalized mechanical pain sensitivity over nerve tissues in patients with strictly unilateral migraine.

    Science.gov (United States)

    Fernández-de-las-Peñas, César; Arendt-Nielsen, Lars; Cuadrado, María Luz; Pareja, Juan A

    2009-06-01

    No study has previously analyzed pressure pain sensitivity of nerve trunks in migraine. This study aimed to examine the differences in mechanical pain sensitivity over specific nerves between patients with unilateral migraine and healthy controls. Blinded investigators assessed pressure pain thresholds (PPT) over the supra-orbital nerves (V1) and peripheral nerve trunks of both upper extremities (median, radial, and ulnar nerves) in 20 patients with strictly unilateral migraine and 20 healthy matched controls. Pain intensity after palpation over both supra-orbital nerves was also assessed. A pressure algometer was used to quantify PPT, whereas a 10-point numerical pain rate scale was used to evaluate pain to palpation over the supra-orbital nerve. The analysis of covariance revealed that pain to palpation over the supra-orbital nerve was significantly higher (P0.6). In patients with unilateral migraine, we found increased mechano-sensitivity of the supra-orbital nerve on the symptomatic side of the head. Outside the head, the same patients showed increased mechano-sensitivity of the main peripheral nerves of both upper limbs, without asymmetries. Such diffuse hypersensitivity of the peripheral nerves lends further evidence to the presence of a state of hyperexcitability of the central nervous system in patients with unilateral migraine.

  2. Strict Criteria for Selection of Laparoscopy for Women with Adnexal Mass

    Science.gov (United States)

    Sallum, Luis Felipe; Sarian, Luis Otávio; Bastos, Joana Fróes Bragança; Derchain, Sophie

    2014-01-01

    Objectives: We compared the indication of laparoscopy for treatment of adnexal masses based on the risk scores and tumor diameters with the indication based on gynecology-oncologists' experience. Methods: This was a prospective study of 174 women who underwent surgery for adnexal tumors (116 laparotomies, 58 laparoscopies). The surgeries begun and completed by laparoscopy, with benign pathologic diagnosis, were considered successful. Laparoscopic surgeries that required conversion to laparotomy, led to a malignant diagnosis, or facilitated cyst rupture were considered failures. Two groups were defined for laparoscopy indication: (1) absence of American College of Obstetrics and Gynecology (ACOG) guideline for referral of high-risk adnexal masses criteria (ACOG negative) associated with 3 different tumor sizes (10, 12, and 14 cm); and (2) Index of Risk of Malignancy (IRM) with cutoffs at 100, 200, and 300, associated with the same 3 tumor sizes. Both groups were compared with the indication based on the surgeon's experience to verify whether the selection based on strict rules would improve the rate of successful laparoscopy. Results: ACOG-negative and tumors ≤10 cm and IRM with a cutoff at 300 points and tumors ≤10cm resulted in the same best performance (78% success = 38/49 laparoscopies). However, compared with the results of the gynecology-oncologists' experience, those were not statistically significant. Discussion: The selection of patients with adnexal mass to laparoscopy by the use of the ACOG guideline or IRM associated with tumor diameter had similar performance as the experience of gynecology-oncologists. Both methods are reproducible and easy to apply to all women with adnexal masses and could be used by general gynecologists to select women for laparoscopic surgery; however, referral to a gynecology-oncologist is advisable when there is any doubt. PMID:25392617

  3. Strict Host-Symbiont Cospeciation and Reductive Genome Evolution in Insect Gut Bacteria

    Science.gov (United States)

    Hosokawa, Takahiro; Kikuchi, Yoshitomo; Nikoh, Naruo; Shimada, Masakazu; Fukatsu, Takema

    2006-01-01

    Host-symbiont cospeciation and reductive genome evolution have been identified in obligate endocellular insect symbionts, but no such example has been identified from extracellular ones. Here we first report such a case in stinkbugs of the family Plataspidae, wherein a specific gut bacterium is vertically transmitted via “symbiont capsule.” In all of the plataspid species, females produced symbiont capsules upon oviposition and their gut exhibited specialized traits for capsule production. Phylogenetic analysis showed that the plataspid symbionts constituted a distinct group in the γ-Proteobacteria, whose sister group was the aphid obligate endocellular symbionts Buchnera. Removal of the symbionts resulted in retarded growth, mortality, and sterility of the insects. The host phylogeny perfectly agreed with the symbiont phylogeny, indicating strict host-symbiont cospeciation despite the extracellular association. The symbionts exhibited AT-biased nucleotide composition, accelerated molecular evolution, and reduced genome size, as has been observed in obligate endocellular insect symbionts. These findings suggest that not the endocellular conditions themselves but the population genetic attributes of the vertically transmitted symbionts are probably responsible for the peculiar genetic traits of these insect symbionts. We proposed the designation “Candidatus Ishikawaella capsulata” for the plataspid symbionts. The plataspid stinkbugs, wherein the host-symbiont associations can be easily manipulated, provide a novel system that enables experimental approaches to previously untouched aspects of the insect-microbe mutualism. Furthermore, comparative analyses of the sister groups, the endocellular Buchnera and the extracellular Ishikawaella, would lead to insights into how the different symbiotic lifestyles have affected their genomic evolution. PMID:17032065

  4. Mining Process Variants: Goals and Issues

    NARCIS (Netherlands)

    Li, J.; Li, C.; Reichert, M.U.; Wombacher, Andreas

    Recently, Process-Aware Information Systems (PAIS) were introduced, which allow for dynamic process and service changes. This, in turn, has led to a large number of process model variants, which are difficult to maintain and expensive to configure. This paper deals with goals and issues related to

  5. Intelligence Community Spending: Trends and Issues

    Science.gov (United States)

    2016-11-08

    Intelligence Community Spending: Trends and Issues Anne Daugherty Miles Analyst in Intelligence and National Security Policy November 8, 2016......Summary This report examines Intelligence Community (IC) funding over the past several decades, with an emphasis on the period from 2007-2017—the

  6. Digital Library Education: Global Trends and Issues

    Science.gov (United States)

    Shem, Magaji

    2015-01-01

    The paper examines trends and issues in digital education programmes globally, drawing examples of developmental growth of Library Information Science (LIS), schools and digital education courses in North America, Britain, and Southern Asia, the slow growth of LIS schools and digital education in Nigeria and some countries in Africa and India. The…

  7. Analyses des discours non strictement mathematiques accompagnant des cours de mathematiques (Analysis of Not Strictly Mathematical Discourse in Mathematics Classes).

    Science.gov (United States)

    Robert, Aline

    1995-01-01

    Examines discourse, not strictly mathematical, that teachers might adopt in a mathematics class and presents three major functions of such discourse: communication; structuring and labeling; and reflection. Develops lines for further inquiry, notably on the third function, the most likely focus for specific preparation by the teacher. (13…

  8. Properties of N-person axiomatic bargaining solutions if the Pareto frontier is twice differentiable and strictly concave

    NARCIS (Netherlands)

    Douven, R.C.M.H.; Engwerda, J.C.

    1995-01-01

    In this paper we discuss properties of N-person axiomatic bargaining problems, where the Pareto frontier of S can be described by a strictly concave and twice differentiable function. These type of problems are characteristic for the empirical policy coordination literature. In that literature the

  9. Convergence of Implicit and Explicit Schemes for an Asymptotically Nonexpansive Mapping in -Uniformly Smooth and Strictly Convex Banach Spaces

    Directory of Open Access Journals (Sweden)

    Meng Wen

    2012-01-01

    Full Text Available We introduce a new iterative scheme with Meir-Keeler contractions for an asymptotically nonexpansive mapping in -uniformly smooth and strictly convex Banach spaces. We also proved the strong convergence theorems of implicit and explicit schemes. The results obtained in this paper extend and improve many recent ones announced by many others.

  10. A non-permselective membrane reactor for chemical processes normally requiring strict stoichiometric feed rates of reactants

    NARCIS (Netherlands)

    Sloot, H.J.; Versteeg, Geert; van Swaaij, Willibrordus Petrus Maria

    1990-01-01

    A novel type of membrane reactor with separated feeding of the reactants is presented for chemical processes normally requiring strict stoichiometric feed rates of premixed reactants. The reactants are fed in the reactor to the different sides of a porous membrane which is impregnated with a

  11. Strict Fathers, Competing Culture(s), and Racialized Poverty: White South African Teachers' Conceptions of Themselves as Racialized Actors

    Science.gov (United States)

    Casey, Zachary A.

    2016-01-01

    This article focuses in particular on four white South African female practicing P-12 teachers' narratives about their own racialized understanding of their classroom practice(s) and their (racio-cultural) self-identity. Each of the four participants reported growing up with what they described as "strict fathers" and shared ways in…

  12. Identité stricte ou partielle et identification dans les phrases à copule. Comment les identifier ?

    Directory of Open Access Journals (Sweden)

    Amary-Coudreau Valérie

    2014-07-01

    éristiques propres à l’identité, ainsi que celles propres à la spécification et à l’identification, pour lesquelles X et Y ont des degrés de référentialité et/ou de prédicativité différents. Enfin, cette hypothèse nous amène à distinguer l’identité de l’identification, sur la base de tests qui, à l’inverse de Larreya (2003, différencient l’identité stricte de l’identité partielle.

  13. Distributed generation: definition, benefits and issues

    International Nuclear Information System (INIS)

    Pepermans, G.; Driesen, J.; Haeseldonckx, D.; Belmans, R.; D'haeseleer, W.

    2005-01-01

    This paper starts from the observation that there is a renewed interest in small-scale electricity generation. The authors start with a survey of existing small-scale generation technologies and then move on with a discussion of the major benefits and issues of small-scale electricity generation. Different technologies are evaluated in terms of their possible contribution to the listed benefits and issues. Small-scale generation is also commonly called distributed generation, embedded generation or decentralised generation. In a final section, an attempt is made to define the latter concepts more precisely. It appears that there is no consensus on a precise definition as the concept encompasses many technologies and applications

  14. Challenges and Issues in Knowledge Management

    DEFF Research Database (Denmark)

    "Challenges and Issues in Knowledge Management" - the fifth volume in the "Research on Management Consulting" series - presents sixteen chapters that explore these various perspectives, focusing on knowledge management within the context of the management consulting industry, the dynamics...... associated with knowledge sharing and dissemination, methodological approaches to studying knowledge in organizations, and reflections on knowledge management and management consulting. As the chapters underscore, it is important to ensure that KM initiatives are aligned with the needs of the organization...

  15. Strict liability as a legal mechanism protecting the aggrieved parties' interests within the nuclear liability regime

    International Nuclear Information System (INIS)

    Novotna, Marianna

    2016-01-01

    The no-fault liability principle of nuclear liability regime, its compensation schemes, sociological and legal grounds of its construction as well as liberation grounds are analysed. The simple existence of causation of damage and nuclear accident without necessity of proving negligence or any other type of fault on the part of the operator as an adequate basis for the operator’s strict liability is highlighted thus simplifying the litigation process eliminating potential obstacles, especially such as might exist with the burden of proof. The question of weighing the interests of society in the development of nuclear industry, the necessary extent of protection of victims of nuclear accidents and the interests of operators of nuclear facilities as main determinants of the strict nature of nuclear liability is also described. (orig.)

  16. The impact of Sleep Time-Related Information and Communication Technology (STRICT) on sleep patterns and daytime functioning in American adolescents.

    Science.gov (United States)

    Polos, Peter G; Bhat, Sushanth; Gupta, Divya; O'Malley, Richard J; DeBari, Vincent A; Upadhyay, Hinesh; Chaudhry, Saqib; Nimma, Anitha; Pinto-Zipp, Genevieve; Chokroverty, Sudhansu

    2015-10-01

    This cross-sectional study explored the extent and impact of mobile device-based Sleep Time-Related Information and Communication Technology (STRICT) use among American adolescents (N = 3139, 49.3% female, mean age = 13.3 years). Nearly 62% used STRICT after bedtime, 56.7% texted/tweeted/messaged in bed, and 20.8% awoke to texts. STRICT use was associated with insomnia, daytime sleepiness, eveningness, academic underperformance, later bedtimes and shorter sleep duration. Moderation analysis demonstrated that the association between STRICT use and insomnia increased with age, the association between STRICT use and daytime sleepiness decreased with age, and the association between STRICT use and shorter sleep duration decreased with age and was stronger in girls. Insomnia and daytime sleepiness partially mediated the relationship between STRICT use and academic underperformance. Our results illustrate the adverse interactions between adolescent STRICT use and sleep, with deleterious effects on daytime functioning. These worrisome findings suggest that placing reasonable limitations on adolescent STRICT use may be appropriate. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  17. Strict versus liberal target range for perioperative glucose in patients undergoing coronary artery bypass grafting: a prospective randomized controlled trial.

    Science.gov (United States)

    Desai, Shalin P; Henry, Linda L; Holmes, Sari D; Hunt, Sharon L; Martin, Chidima T; Hebsur, Shrinivas; Ad, Niv

    2012-02-01

    The purpose of this study was to test the hypothesis that a liberal blood glucose strategy (121-180 mg/dL) is not inferior to a strict blood glucose strategy (90-120 mg/dL) for outcomes in patients after first-time isolated coronary artery bypass grafting and is superior for glucose control and target blood glucose management. A total of 189 patients undergoing coronary artery bypass grafting were investigated in this prospective randomized study to compare 2 glucose control strategies on patient perioperative outcomes. Three methods of analyses (intention to treat, completer, and per protocol) were conducted. Observed power was robust (>80%) for significant results. The groups were similar on preoperative hemoglobin A(1c) and number of diabetic patients. The liberal group was found to be noninferior to the strict group for perioperative complications and superior on glucose control and target range management. The liberal group had significantly fewer patients with hypoglycemic events (liberal range after coronary artery bypass grafting led to similar outcomes compared with a strict target range and was superior in glucose control and target range management. On the basis of the results of this study, a target blood glucose range of 121 to 180 mg/dL is recommended for patients after coronary artery bypass grafting as advocated by the Society of Thoracic Surgeons. Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

  18. Challenges and Issues in Knowledge Management

    DEFF Research Database (Denmark)

    "Challenges and Issues in Knowledge Management" - the fifth volume in the "Research on Management Consulting" series - presents sixteen chapters that explore these various perspectives, focusing on knowledge management within the context of the management consulting industry, the dynamics...... associated with knowledge sharing and dissemination, methodological approaches to studying knowledge in organizations, and reflections on knowledge management and management consulting. As the chapters underscore, it is important to ensure that KM initiatives are aligned with the needs of the organization...... and its members, that the KM system is "owned" by organizational members with particular emphasis on executive sponsorship and team member acceptance, and that it be understood as an ongoing process rather than simply another management objective or faddish consulting tool. The focus, therefore, should...

  19. Depreciating Indian Rupee: Trends and Issues

    Directory of Open Access Journals (Sweden)

    BADAR ALAM IQBAL

    2015-05-01

    Full Text Available Indian rupee has been depreciating since May 2013 creating many dimensional trends and issues to be looked at or to be examined. If a currency is depreciating it implies that the value has gone down in relation to another currency. Presently, the value of rupee has declined from nearly Rs. 55 to a dollar to nearly 69 rupees a dollar. This is because portfolio investors are now taking back their money from emerging markets causing demand for dollars (international currency for payments to increase hence, pulling down Indian currency. The present paper analyzing the deprecating trends since independence in the context of Indian economy and also discusses issues which have come up due to depreciation of Indian rupee.

  20. Effectiveness of strict vs. multiple use protected areas in reducing tropical forest fires: a global analysis using matching methods.

    Directory of Open Access Journals (Sweden)

    Andrew Nelson

    Full Text Available Protected areas (PAs cover a quarter of the tropical forest estate. Yet there is debate over the effectiveness of PAs in reducing deforestation, especially when local people have rights to use the forest. A key analytic problem is the likely placement of PAs on marginal lands with low pressure for deforestation, biasing comparisons between protected and unprotected areas. Using matching techniques to control for this bias, this paper analyzes the global tropical forest biome using forest fires as a high resolution proxy for deforestation; disaggregates impacts by remoteness, a proxy for deforestation pressure; and compares strictly protected vs. multiple use PAs vs indigenous areas. Fire activity was overlaid on a 1 km map of tropical forest extent in 2000; land use change was inferred for any point experiencing one or more fires. Sampled points in pre-2000 PAs were matched with randomly selected never-protected points in the same country. Matching criteria included distance to road network, distance to major cities, elevation and slope, and rainfall. In Latin America and Asia, strict PAs substantially reduced fire incidence, but multi-use PAs were even more effective. In Latin America, where there is data on indigenous areas, these areas reduce forest fire incidence by 16 percentage points, over two and a half times as much as naïve (unmatched comparison with unprotected areas would suggest. In Africa, more recently established strict PAs appear to be effective, but multi-use tropical forest protected areas yield few sample points, and their impacts are not robustly estimated. These results suggest that forest protection can contribute both to biodiversity conservation and CO2 mitigation goals, with particular relevance to the REDD agenda. Encouragingly, indigenous areas and multi-use protected areas can help to accomplish these goals, suggesting some compatibility between global environmental goals and support for local livelihoods.

  1. Hydroxycinnamic acids used as external acceptors of electrons: an energetic advantage for strictly heterofermentative lactic acid bacteria.

    Science.gov (United States)

    Filannino, Pasquale; Gobbetti, Marco; De Angelis, Maria; Di Cagno, Raffaella

    2014-12-01

    The metabolism of hydroxycinnamic acids by strictly heterofermentative lactic acid bacteria (19 strains) was investigated as a potential alternative energy route. Lactobacillus curvatus PE5 was the most tolerant to hydroxycinnamic acids, followed by strains of Weissella spp., Lactobacillus brevis, Lactobacillus fermentum, and Leuconostoc mesenteroides, for which the MIC values were the same. The highest sensitivity was found for Lactobacillus rossiae strains. During growth in MRS broth, lactic acid bacteria reduced caffeic, p-coumaric, and ferulic acids into dihydrocaffeic, phloretic, and dihydroferulic acids, respectively, or decarboxylated hydroxycinnamic acids into the corresponding vinyl derivatives and then reduced the latter compounds to ethyl compounds. Reductase activities mainly emerged, and the activities of selected strains were further investigated in chemically defined basal medium (CDM) under anaerobic conditions. The end products of carbon metabolism were quantified, as were the levels of intracellular ATP and the NAD(+)/NADH ratio. Electron and carbon balances and theoretical ATP/glucose yields were also estimated. When CDM was supplemented with hydroxycinnamic acids, the synthesis of ethanol decreased and the concentration of acetic acid increased. The levels of these metabolites reflected on the alcohol dehydrogenase and acetate kinase activities. Overall, some biochemical traits distinguished the common metabolism of strictly heterofermentative strains: main reductase activity toward hydroxycinnamic acids, a shift from alcohol dehydrogenase to acetate kinase activities, an increase in the NAD(+)/NADH ratio, and the accumulation of supplementary intracellular ATP. Taken together, the above-described metabolic responses suggest that strictly heterofermentative lactic acid bacteria mainly use hydroxycinnamic acids as external acceptors of electrons. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  2. Fermentative Degradation of Polyethylene Glycol by a Strictly Anaerobic, Gram-Negative, Nonsporeforming Bacterium, Pelobacter venetianus sp. nov

    OpenAIRE

    1983-01-01

    The synthetic polyether polyethylene glycol (PEG) with a molecular weight of 20,000 was anaerobically degraded in enrichment cultures inoculated with mud of limnic and marine origins. Three strains (Gra PEG 1, Gra PEG 2, and Ko PEG 2) of rod-shaped, gram-negative, nonsporeforming, strictly anaerobic bacteria were isolated in mineral medium with PEG as the sole source of carbon and energy. All strains degraded dimers, oligomers, and polymers of PEG up to a molecular weight of 20,000 completely...

  3. An Iterative Algorithm Combining Viscosity Method with Parallel Method for a Generalized Equilibrium Problem and Strict Pseudocontractions

    Directory of Open Access Journals (Sweden)

    2009-03-01

    Full Text Available We introduce a new approximation scheme combining the viscosity method with parallel method for finding a common element of the set of solutions of a generalized equilibrium problem and the set of fixed points of a family of finitely strict pseudocontractions. We obtain a strong convergence theorem for the sequences generated by these processes in Hilbert spaces. Based on this result, we also get some new and interesting results. The results in this paper extend and improve some well-known results in the literature.

  4. Adaptive terminal sliding mode control for hypersonic flight vehicles with strictly lower convex function based nonlinear disturbance observer.

    Science.gov (United States)

    Wu, Yun-Jie; Zuo, Jing-Xing; Sun, Liang-Hua

    2017-11-01

    In this paper, the altitude and velocity tracking control of a generic hypersonic flight vehicle (HFV) is considered. A novel adaptive terminal sliding mode controller (ATSMC) with strictly lower convex function based nonlinear disturbance observer (SDOB) is proposed for the longitudinal dynamics of HFV in presence of both parametric uncertainties and external disturbances. First, for the sake of enhancing the anti-interference capability, SDOB is presented to estimate and compensate the equivalent disturbances by introducing a strictly lower convex function. Next, the SDOB based ATSMC (SDOB-ATSMC) is proposed to guarantee the system outputs track the reference trajectory. Then, stability of the proposed control scheme is analyzed by the Lyapunov function method. Compared with other HFV control approaches, key novelties of SDOB-ATSMC are that a novel SDOB is proposed and drawn into the (virtual) control laws to compensate the disturbances and that several adaptive laws are used to deal with the differential explosion problem. Finally, it is illustrated by the simulation results that the new method exhibits an excellent robustness and a better disturbance rejection performance than the convention approach. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

  5. Strictly monolayer large continuous MoS{sub 2} films on diverse substrates and their luminescence properties

    Energy Technology Data Exchange (ETDEWEB)

    Mohapatra, P. K.; Deb, S.; Singh, B. P.; Vasa, P.; Dhar, S., E-mail: dhar@phy.iitb.ac.in [Department of Physics, Indian Institute of Technology Bombay, Mumbai 400076 (India)

    2016-01-25

    Despite a tremendous interest on molybdenum disulfide as a thinnest direct band gap semiconductor, single step synthesis of a large area purely monolayer MoS{sub 2} film has not yet been reported. Here, we report a CVD route to synthesize a continuous film of strictly monolayer MoS{sub 2} covering an area as large as a few cm{sup 2} on a variety of different substrates without using any seeding material or any elaborate pretreatment of the substrate. This is achieved by allowing the growth to take place in the naturally formed gap between a piece of SiO{sub 2} coated Si wafer and the substrate, when the latter is placed on top of the former inside a CVD reactor. We propose a qualitative model to explain why the MoS{sub 2} films are always strictly monolayer in this method. The photoluminescence study of these monolayers shows the characteristic excitonic and trionic features associated with monolayer MoS{sub 2}. In addition, a broad defect related luminescence band appears at ∼1.7 eV. As temperature decreases, the intensity of this broad feature increases, while the band edge luminescence reduces.

  6. Event-Sampled Direct Adaptive NN Output- and State-Feedback Control of Uncertain Strict-Feedback System.

    Science.gov (United States)

    Szanto, Nathan; Narayanan, Vignesh; Jagannathan, Sarangapani

    2017-04-12

    In this paper, a novel event-triggered implementation of a tracking controller for an uncertain strict-feedback system is presented. Neural networks (NNs) are utilized in the backstepping approach to design a control input by approximating unknown dynamics of the strict-feedback nonlinear system with event-sampled inputs. The system state vector is assumed to be unknown and an NN observer is used to estimate the state vector. By using the estimated state vector and backstepping design approach, an event-sampled controller is introduced. As part of the controller design, first, input-to-state-like stability for a continuously sampled controller that has been injected with bounded measurement errors is demonstrated, and subsequently, an event-execution control law is derived, such that the measurement errors are guaranteed to remain bounded. Lyapunov theory is used to demonstrate that the tracking errors, the observer estimation errors, and the NN weight estimation errors for each NN are locally uniformly ultimately bounded in the presence bounded disturbances, NN reconstruction errors, as well as errors introduced by event sampling. Simulation results are provided to illustrate the effectiveness of the proposed controllers.

  7. Strict fibonacci heaps

    DEFF Research Database (Denmark)

    Brodal, Gerth Stølting; Lagogiannis, George; Tarjan, Robert E.

    2012-01-01

    We present the first pointer-based heap implementation with time bounds matching those of Fibonacci heaps in the worst case. We support make-heap, insert, find-min, meld and decrease-key in worst-case O(1) time, and delete and delete-min in worst-case O(lg n) time, where n is the size of the heap...... of the smaller heap when doing a meld. We use the pigeonhole principle in place of the redundant counter mechanism. We present the first pointer-based heap implementation with time bounds matching those of Fibonacci heaps in the worst case. We support make-heap, insert, find-min, meld and decrease-key in worst...

  8. Online Recorded Data-Based Composite Neural Control of Strict-Feedback Systems With Application to Hypersonic Flight Dynamics.

    Science.gov (United States)

    Xu, Bin; Yang, Daipeng; Shi, Zhongke; Pan, Yongping; Chen, Badong; Sun, Fuchun

    2017-09-25

    This paper investigates the online recorded data-based composite neural control of uncertain strict-feedback systems using the backstepping framework. In each step of the virtual control design, neural network (NN) is employed for uncertainty approximation. In previous works, most designs are directly toward system stability ignoring the fact how the NN is working as an approximator. In this paper, to enhance the learning ability, a novel prediction error signal is constructed to provide additional correction information for NN weight update using online recorded data. In this way, the neural approximation precision is highly improved, and the convergence speed can be faster. Furthermore, the sliding mode differentiator is employed to approximate the derivative of the virtual control signal, and thus, the complex analysis of the backstepping design can be avoided. The closed-loop stability is rigorously established, and the boundedness of the tracking error can be guaranteed. Through simulation of hypersonic flight dynamics, the proposed approach exhibits better tracking performance.

  9. Global neural dynamic surface tracking control of strict-feedback systems with application to hypersonic flight vehicle.

    Science.gov (United States)

    Xu, Bin; Yang, Chenguang; Pan, Yongping

    2015-10-01

    This paper studies both indirect and direct global neural control of strict-feedback systems in the presence of unknown dynamics, using the dynamic surface control (DSC) technique in a novel manner. A new switching mechanism is designed to combine an adaptive neural controller in the neural approximation domain, together with the robust controller that pulls the transient states back into the neural approximation domain from the outside. In comparison with the conventional control techniques, which could only achieve semiglobally uniformly ultimately bounded stability, the proposed control scheme guarantees all the signals in the closed-loop system are globally uniformly ultimately bounded, such that the conventional constraints on initial conditions of the neural control system can be relaxed. The simulation studies of hypersonic flight vehicle (HFV) are performed to demonstrate the effectiveness of the proposed global neural DSC design.

  10. Iterative algorithms for the input and state recovery from the approximate inverse of strictly proper multivariable systems

    Science.gov (United States)

    Chen, Liwen; Xu, Qiang

    2018-02-01

    This paper proposes new iterative algorithms for the unknown input and state recovery from the system outputs using an approximate inverse of the strictly proper linear time-invariant (LTI) multivariable system. One of the unique advantages from previous system inverse algorithms is that the output differentiation is not required. The approximate system inverse is stable due to the systematic optimal design of a dummy feedthrough D matrix in the state-space model via the feedback stabilization. The optimal design procedure avoids trial and error to identify such a D matrix which saves tremendous amount of efforts. From the derived and proved convergence criteria, such an optimal D matrix also guarantees the convergence of algorithms. Illustrative examples show significant improvement of the reference input signal tracking by the algorithms and optimal D design over non-iterative counterparts on controllable or stabilizable LTI systems, respectively. Case studies of two Boeing-767 aircraft aerodynamic models further demonstrate the capability of the proposed methods.

  11. Monolithic InP strictly non-blocking 8×8 switch for high-speed WDM optical interconnection.

    Science.gov (United States)

    Kwack, Myung-Joon; Tanemura, Takuo; Higo, Akio; Nakano, Yoshiaki

    2012-12-17

    A strictly non-blocking 8 × 8 switch for high-speed WDM optical interconnection is realized on InP by using the phased-array scheme for the first time. The matrix switch architecture consists of over 200 functional devices such as star couplers, phase-shifters and so on without any waveguide cross-section. We demonstrate ultra-broad optical bandwidth covering the entire C-band through several Input/Output ports combination with extinction ratio performance of more than 20dB. Also, nanoseconds reconfiguration time was successfully achieved by dynamic switching experiment. Error-free transmission was verified for 40-Gbps (10-Gbps × 4ch) WDM signal.

  12. The LHC Continuous Cryostat Interconnections The Organization of a Logistically Complex Worksite Requiring Strict Quality Standards and High Output

    CERN Document Server

    Fessia, P; Bozzini, D; Cruikshank, P; Jacquemod, A; Maan, W; Musso, A; Oberli, L; Poncet, A; Russenschuck, Stephan; Savary, F; Struik, M; Tock, J Ph; Tommasini, D; Völlinger, C; Kotarba, A; Olek, S; Sulek, Z; Grimaud, A; Vaudaux, L

    2008-01-01

    The interconnections of the Large Hadron Collider (LHC) continuous cryostat have been completed in fall 2007: 1695 interconnections magnet to magnet and 224 interconnections between the continuous cryostat and the cryogenic distribution line have been executed along the 27 km of the LHC. The very tight schedule, the complexity of the interconnection sequence, the strict quality standards applied have required the creation of an ad hoc organization in order to steer and coordinate the activities on the worksite dispersed along the whole accelerator ring. The concatenation of construction and test phases carried out by CERN staff, CERN collaborating institutes and contractors have led to the necessity of a common approach and of a very effective information flow. In this paper, after having recalled the main technical challenges, we review the organizational choices that have been taken and we briefly analyze the development of the worksite in term of allocated resources and production.

  13. Analysis of strictly bound modes in photonic crystal fibers by use of a source-model technique.

    Science.gov (United States)

    Hochman, Amit; Leviatan, Yehuda

    2004-06-01

    We describe a source-model technique for the analysis of the strictly bound modes propagating in photonic crystal fibers that have a finite photonic bandgap crystal cladding and are surrounded by an air jacket. In this model the field is simulated by a superposition of fields of fictitious electric and magnetic current filaments, suitably placed near the media interfaces of the fiber. A simple point-matching procedure is subsequently used to enforce the continuity conditions across the interfaces, leading to a homogeneous matrix equation. Nontrivial solutions to this equation yield the mode field patterns and propagation constants. As an example, we analyze a hollow-core photonic crystal fiber. Symmetry characteristics of the modes are discussed and exploited to reduce the computational burden.

  14. Development of a PCR assay based on the 16S-23S rDNA internal transcribed spacer for identification of strictly anaerobic bacterium Zymophilus

    Czech Academy of Sciences Publication Activity Database

    Felsberg, Jürgen; Jelínková, Markéta; Kubizniaková, P.; Matoulková, D.

    2015-01-01

    Roč. 33, June (2015), s. 85-89 ISSN 1075-9964 Institutional support: RVO:61388971 Keywords : Brewing microbiology * Strictly anaerobic bacteria * Yeast contamination Subject RIV: GM - Food Processing Impact factor: 2.424, year: 2015

  15. Strict blood glucose control by an artificial endocrine pancreas during hepatectomy may prevent postoperative acute kidney injury.

    Science.gov (United States)

    Mita, Naoji; Kawahito, Shinji; Soga, Tomohiro; Takaishi, Kazumi; Kitahata, Hiroshi; Matsuhisa, Munehide; Shimada, Mitsuo; Kinoshita, Hiroyuki; Tsutsumi, Yasuo M; Tanaka, Katsuya

    2017-03-01

    The aim of the present study was to evaluate the usefulness of a closed-loop system (STG-55; Nikkiso, Tokyo, Japan), a type of artificial endocrine pancreas for the continuous monitoring and control of intraoperative blood glucose, for preventing postoperative acute kidney injury (AKI) in patients undergoing hepatectomy. Thirty-eight patients were enrolled in this study. Glucose concentrations were controlled with either a manual injection of insulin based on a commonly used sliding scale (manual insulin group, n = 19) or the programmed infusion of insulin determined by the control algorithm of the artificial endocrine pancreas (programmed insulin group, n = 19). After the induction of anesthesia, a 20-G intravenous catheter was inserted into the peripheral forearm vein of patients in the programmed insulin group and connected to an artificial endocrine pancreas (STG-55). The target range for glucose concentrations was set to 100-150 mg/dL. The mean serum creatinine concentrations of preoperative, postoperative 24 and 48 h were 0.72, 0.78, and 0.79 mg/dL in the programmed insulin group, and 0.81, 0.95, and 1.03 mg/dL in the manual insulin group, respectively. Elevations in serum creatinine concentrations postoperative 48 h were significantly suppressed in the programmed insulin group. The STG-55 closed-loop system was effective for maintaining strict blood glucose control during hepatectomy with minimal variability in blood glucose concentrations and for suppressing elevations in serum creatinine concentrations. Strict blood glucose control by an artificial endocrine pancreas during hepatectomy may prevent postoperative AKI.

  16. Intra-Genomic Heterogeneity in 16S rRNA Genes in Strictly Anaerobic Clinical Isolates from Periodontal Abscesses

    Science.gov (United States)

    Chen, Jiazhen; Miao, Xinyu; Xu, Meng; He, Junlin; Xie, Yi; Wu, Xingwen; Chen, Gang; Yu, Liying; Zhang, Wenhong

    2015-01-01

    Background Members of the genera Prevotella, Veillonella and Fusobacterium are the predominant culturable obligate anaerobic bacteria isolated from periodontal abscesses. When determining the cumulative number of clinical anaerobic isolates from periodontal abscesses, ambiguous or overlapping signals were frequently encountered in 16S rRNA gene sequencing chromatograms, resulting in ambiguous identifications. With the exception of the genus Veillonella, the high intra-chromosomal heterogeneity of rrs genes has not been reported. Methods The 16S rRNA genes of 138 clinical, strictly anaerobic isolates and one reference strain were directly sequenced, and the chromatograms were carefully examined. Gene cloning was performed for 22 typical isolates with doublet sequencing signals for the 16S rRNA genes, and four copies of the rrs-ITS genes of 9 Prevotella intermedia isolates were separately amplified by PCR, sequenced and compared. Five conserved housekeeping genes, hsp60, recA, dnaJ, gyrB1 and rpoB from 89 clinical isolates of Prevotella were also amplified by PCR and sequenced for identification and phylogenetic analysis along with 18 Prevotella reference strains. Results Heterogeneity of 16S rRNA genes was apparent in clinical, strictly anaerobic oral bacteria, particularly in the genera Prevotella and Veillonella. One hundred out of 138 anaerobic strains (72%) had intragenomic nucleotide polymorphisms (SNPs) in multiple locations, and 13 strains (9.4%) had intragenomic insertions or deletions in the 16S rRNA gene. In the genera Prevotella and Veillonella, 75% (67/89) and 100% (19/19) of the strains had SNPs in the 16S rRNA gene, respectively. Gene cloning and separate amplifications of four copies of the rrs-ITS genes confirmed that 2 to 4 heterogeneous 16S rRNA copies existed. Conclusion Sequence alignment of five housekeeping genes revealed that intra-species nucleotide similarities were very high in the genera Prevotella, ranging from 94.3–100%. However, the

  17. Fermentative degradation of polyethylene glycol by a strictly anaerobic, gram-negative, nonsporeforming bacterium, Pelobacter venetianus sp. nov.

    Science.gov (United States)

    Schink, B; Stieb, M

    1983-06-01

    The synthetic polyether polyethylene glycol (PEG) with a molecular weight of 20,000 was anaerobically degraded in enrichment cultures inoculated with mud of limnic and marine origins. Three strains (Gra PEG 1, Gra PEG 2, and Ko PEG 2) of rod-shaped, gram-negative, nonsporeforming, strictly anaerobic bacteria were isolated in mineral medium with PEG as the sole source of carbon and energy. All strains degraded dimers, oligomers, and polymers of PEG up to a molecular weight of 20,000 completely by fermentation to nearly equal amounts of acetate and ethanol. The monomer ethylene glycol was not degraded. An ethylene glycol-fermenting anaerobe (strain Gra EG 12) isolated from the same enrichments was identified as Acetobacterium woodii. The PEG-fermenting strains did not excrete extracellular depolymerizing enzymes and were inhibited by ethylene glycol, probably owing to a blocking of the cellular uptake system. PEG, some PEG-containing nonionic detergents, 1,2-propanediol, 1,2-butanediol, glycerol, and acetoin were the only growth substrates utilized of a broad variety of sugars, organic acids, and alcohols. The isolates did not reduce sulfate, sulfur, thiosulfate, or nitrate and were independent of growth factors. In coculture with A. woodii or Methanospirillum hungatei, PEGs and ethanol were completely fermented to acetate (and methane). A marine isolate is described as the type strain of a new species, Pelobacter venetianus sp. nov. Its physiology and ecological significance, as well as the importance and possible mechanism of anaerobic polyether degradation, are discussed.

  18. Molecular mechanism of strict substrate specificity of an extradiol dioxygenase, DesB, derived from Sphingobium sp. SYK-6.

    Directory of Open Access Journals (Sweden)

    Keisuke Sugimoto

    Full Text Available DesB, which is derived from Sphingobium sp. SYK-6, is a type II extradiol dioxygenase that catalyzes a ring opening reaction of gallate. While typical extradiol dioxygenases show broad substrate specificity, DesB has strict substrate specificity for gallate. The substrate specificity of DesB seems to be required for the efficient growth of S. sp. SYK-6 using lignin-derived aromatic compounds. Since direct coordination of hydroxyl groups of the substrate to the non-heme iron in the active site is a critical step for the catalytic reaction of the extradiol dioxygenases, the mechanism of the substrate recognition and coordination of DesB was analyzed by biochemical and crystallographic methods. Our study demonstrated that the direct coordination between the non-heme iron and hydroxyl groups of the substrate requires a large shift of the Fe (II ion in the active site. Mutational analysis revealed that His124 and His192 in the active site are essential to the catalytic reaction of DesB. His124, which interacts with OH (4 of the bound gallate, seems to contribute to proper positioning of the substrate in the active site. His192, which is located close to OH (3 of the gallate, is likely to serve as the catalytic base. Glu377' interacts with OH (5 of the gallate and seems to play a critical role in the substrate specificity. Our biochemical and structural study showed the substrate recognition and catalytic mechanisms of DesB.

  19. Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight: a randomized controlled clinical trial.

    Science.gov (United States)

    Weidlich, Patricia; Moreira, Carlos Heitor C; Fiorini, Tiago; Musskopf, Marta L; da Rocha, José M; Oppermann, Maria Lucia R; Aass, Anne M; Gjermo, Per; Susin, Cristiano; Rösing, Cassiano K; Oppermann, Rui V

    2013-01-01

    This randomized controlled clinical trial was carried out to assess the effect of comprehensive nonsurgical periodontal treatment and strict plaque control performed during pregnancy on the reduction of preterm and/or low birth weight rates (PTLBW). Three hundred and three women were randomly allocated to receive periodontal treatment either during pregnancy (n = 147, test group) or after delivery (n = 156, control group). During pregnancy, the control group received only one session of supragingival scaling and oral hygiene instruction. In contrast, the test group received comprehensive periodontal treatment including multiple sessions of scaling and root planing, oral hygiene instructions, and frequent maintenance visits. At baseline, periodontal inflammation was observed in approximately 50% of sites and attachment loss affected controls, women in the test group had significant reductions in the percentage of sites with plaque (48.5% vs. 10.3%, p control significantly improved periodontal health; however, no reduction of PTLBW rates was observed. Thus, remaining periodontal inflammation posttreatment cannot explain the lack of effect of periodontal treatment on PTLBW. Clinical relevance This study demonstrated that periodontal diseases may be successfully treated during pregnancy. Our results do not support a potential beneficial effect of periodontal treatment on PTLBW.

  20. Nutritionally recommended food for semi- to strict vegetarian diets based on large-scale nutrient composition data.

    Science.gov (United States)

    Kim, Seunghyeon; Fenech, Michael F; Kim, Pan-Jun

    2018-03-12

    Diet design for vegetarian health is challenging due to the limited food repertoire of vegetarians. This challenge can be partially overcome by quantitative, data-driven approaches that utilise massive nutritional information collected for many different foods. Based on large-scale data of foods' nutrient compositions, the recent concept of nutritional fitness helps quantify a nutrient balance within each food with regard to satisfying daily nutritional requirements. Nutritional fitness offers prioritisation of recommended foods using the foods' occurrence in nutritionally adequate food combinations. Here, we systematically identify nutritionally recommendable foods for semi- to strict vegetarian diets through the computation of nutritional fitness. Along with commonly recommendable foods across different diets, our analysis reveals favourable foods specific to each diet, such as immature lima beans for a vegan diet as an amino acid and choline source, and mushrooms for ovo-lacto vegetarian and vegan diets as a vitamin D source. Furthermore, we find that selenium and other essential micronutrients can be subject to deficiency in plant-based diets, and suggest nutritionally-desirable dietary patterns. We extend our analysis to two hypothetical scenarios of highly personalised, plant-based methionine-restricted diets. Our nutrient-profiling approach may provide a useful guide for designing different types of personalised vegetarian diets.

  1. Lack of evidence for phase-only control of retinal photoisomerization in the strict one-photon limit

    Science.gov (United States)

    Liebel, M.; Kukura, P.

    2017-01-01

    The concept of shaping electric fields to steer light-induced processes coherently has fascinated scientists for decades. Despite early theoretical considerations that ruled out one-photon coherent control (CC), several experimental studies reported that molecular responses are sensitive to the shape of the excitation field in the weak-field limit. These observations were largely attributed to the presence of rapid-decay channels, but experimental verification is lacking. Here, we test this hypothesis by investigating the degree of achievable control over the photoisomerization of the retinal protonated Schiff-base in bacteriorhodopsin, isorhodopsin and rhodopsin, all of which exhibit similar chromophores but different isomerization yields and excited-state lifetimes. Irrespective of the system studied, we find no evidence for dissipation-dependent behaviour, nor for any CC in the strict one-photon limit. Our results question the extent to which a photochemical process at ambient conditions can be controlled at the amplitude level, and how the underlying molecular potential-energy surfaces and dynamics may influence this controllability.

  2. Effect of strict metabolic control on regulation of subcutaneous blood flow in insulin-dependent diabetic patients

    DEFF Research Database (Denmark)

    Kastrup, J; Mathiesen, E R; Saurbrey, Nina

    1987-01-01

    washout technique. Mean arterial blood pressure was reduced by a maximum of 23 mmHg by elevating the limb above heart level and elevated to a maximum of 65 mmHg by head-up tilt; in the latter position venous pressure was kept constantly low by activation of the leg muscle vein pump (heel raising......The effect of 10 weeks of improved metabolic control on the impaired autoregulation of the subcutaneous blood flow was studied at the level of the lateral malleolus in eight long-term insulin-dependent diabetic patients with clinical microangiopathy. Blood flow was measured by the local 133-Xenon......). Improved metabolic control was achieved using either continuous subcutaneous insulin infusion or multiple insulin injections. The blood glucose concentration declined from (median) 12.7 to 6.8 mmol/l and the HbA1C level from 10.1 to 7.5% during strict metabolic control (p less than 0.01 and p less than 0...

  3. 29 CFR 511.10 - Subjects and issues.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Subjects and issues. 511.10 Section 511.10 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS WAGE ORDER PROCEDURE FOR AMERICAN SAMOA § 511.10 Subjects and issues. (a) The declared policy of the Act with respect...

  4. 47 CFR 1.331 - Who may sign and issue.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Who may sign and issue. 1.331 Section 1.331 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Hearing Proceedings Subpenas § 1.331 Who may sign and issue. Subpenas requiring the attendance and testimony of witnesses, and subpenas...

  5. A novel strictly anaerobic recovery and enrichment system incorporating lithium for detection of heat-injured Listeria monocytogenes in pasteurized milk containing background microflora.

    Science.gov (United States)

    Mendonca, A F; Knabel, S J

    1994-11-01

    Heat-injured cells of Listeria monocytogenes were recovered from heated raw milk containing noninjured Enterococcus faecium by combining a simple method for obtaining strict anaerobiosis with a novel enrichment broth, Penn State University broth (PSU broth). Strictly anaerobic conditions were rapidly achieved by adding 0.5 g of filter-sterilized cysteine per liter to PSU broth and then purging the preparation with N2 gas. Little resuscitation or growth occurred in strictly anaerobic PSU broth without lithium chloride because of overgrowth by E. faecium. The growth of E. faecium decreased dramatically with increasing LiCl concentration; LiCl concentrations of 8 and 10 g/liter were completely bacteriostatic. The mechanism of inhibition by LiCl appeared to involve competition with the divalent cations Ca2+ and Mg2+. Heat-injured L. monocytogenes consistently recovered and grew rapidly in strictly anaerobic PSU broth containing 4, 6, or 7 g of LiCl per liter. The use of strictly anaerobic PSU broth containing 7 g of LiCl per liter permitted detection of severely heat-injured L. monocytogenes in one simple recovery-enrichment step by eliminating oxygen toxicity and inhibiting the growth of background microflora, without preventing the resuscitation and subsequent growth of heat-injured L. monocytogenes. L. monocytogenes heated in raw milk at 62.8 degrees C for 10, 15, and 20 min could be consistently recovered from strictly anaerobic PSU broth enrichment cultures at 30 degrees C after 48, 96, and 144 h, respectively, and hence, use of PSU broth may result in better recovery of both injured and noninjured cells from foods than currently used U.S. Department of Agriculture and Food and Drug Administration preenrichment procedures.

  6. Novel microsatellite DNA markers indicate strict parthenogenesis and few genotypes in the invasive willow sawfly Nematus oligospilus.

    Science.gov (United States)

    Caron, V; Norgate, M; Ede, F J; Nyman, T; Sunnucks, P

    2013-02-01

    Invasive organisms can have major impacts on the environment. Some invasive organisms are parthenogenetic in their invasive range and, therefore, exist as a number of asexual lineages (=clones). Determining the reproductive mode of invasive species has important implications for understanding the evolutionary genetics of such species, more especially, for management-relevant traits. The willow sawfly Nematus oligospilus Förster (Hymenoptera: Tenthredinidae) has been introduced unintentionally into several countries in the Southern Hemisphere where it has subsequently become invasive. To assess the population expansion, reproductive mode and host-plant relationships of this insect, microsatellite markers were developed and applied to natural populations sampled from the native and expanded range, along with sequencing of the cytochrome-oxidase I mitochondrial DNA (mtDNA) region. Other tenthredinids across a spectrum of taxonomic similarity to N. oligospilus and having a range of life strategies were also tested. Strict parthenogenesis was apparent within invasive N. oligospilus populations throughout the Southern Hemisphere, which comprised only a small number of genotypes. Sequences of mtDNA were identical for all individuals tested in the invasive range. The microsatellite markers were used successfully in several sawfly species, especially Nematus spp. and other genera of the Nematini tribe, with the degree of success inversely related to genetic divergence as estimated from COI sequences. The confirmation of parthenogenetic reproduction in N. oligospilus and the fact that it has a very limited pool of genotypes have important implications for understanding and managing this species and its biology, including in terms of phenotypic diversity, host relationships, implications for spread and future adaptive change. It would appear to be an excellent model study system for understanding evolution of invasive parthenogens that diverge without sexual reproduction and

  7. Sporothrix schenckii (sensu strict S. globosa) mating type 1-2 (MAT1-2) gene.

    Science.gov (United States)

    Kano, Rui; Anzawa, Kazushi; Mochizuki, Takashi; Nishimoto, Katsutaro; Hiruma, Masataro; Kamata, Hiroshi; Hasegawa, Atsuhiko

    2013-09-01

    Sporotix schenckii is a pathogenic fungus that causes human and animal sporotrichosis, and based on morphology of the sessile conidia and molecular analysis, it was recently recognized as a species complex comprising at least the following six sibling species: S. albicans, S. brasiliensis, S. globosa, S. luriei, S. mexicana and S. schenckii. However, apart from S. schenckii sensu strict, only S. brasiliensis, S. globosa and S. luriei are associated with human and animal infection. S. globosa has been most commonly isolated in Asia, Europe and the USA; therefore, molecular epidemiological study for S. globosa is important in relation to human sporotrichosis in Japan. To the best of our knowledge, this is the first study to determine the mating type 1-2 (MAT1-2) gene of Sporothrix schenckii with the aim of understanding the taxonomy of the genus Sporothrix. The MAT1-2 gene (1618 bp) encodes a protein sequence of 198 amino acids. Reverse transcription polymerase chain reaction analysis also detected MAT1-2 gene mRNA expression in all of the S. schenckii strains examined, indicating that this gene is expressed in S. schenckii cells. Phylogenetic analysis of the MAT1-2 gene fragments of Ophiostoma himal-ulmi, O. novo-ulmi, O. ulmi and S. schenckii indicated that these isolates could be classified into four clusters. MAT1-1 gene-specific polymerase chain reaction was positive in 15 isolates, but negative in four human isolates and one feline isolate. © 2013 Japanese Dermatological Association.

  8. Changes in Frequency Intake of Foods in Patients Undergoing Sleeve Gastrectomy and Following a Strict Dietary Control.

    Science.gov (United States)

    Ruiz-Tovar, Jaime; Bozhychko, Maryana; Del-Campo, Jone Miren; Boix, Evangelina; Zubiaga, Lorea; Muñoz, Jose Luis; Llavero, Carolina

    2017-12-17

    Dietary intake and food preferences change after bariatric surgery, secondary to gastrointestinal symptoms and dietitian counseling. The aim of this study was to evaluate the changes in the frequency intake of different foods in patients undergoing sleeve gastrectomy and following a strict dietary control. A prospective observational study of all the morbidly obese patients undergoing laparoscopic sleeve gastrectomy as bariatric procedure between 2007 and 2012 was performed. Dietary assessment was performed using the Alimentary Frequency Questionnaire 1991-2002, developed and validated by the Department of Epidemiology of Miguel Hernandez University (Elche, Alicante Spain). Ninety-three patients were included for analysis, 73 females and 20 males, with a mean preoperative BMI of 46.4 ± 7.9 kg/m 2 . One year after surgery, excess weight loss was 81.1 ± 8.3% and 5 years after surgery, 79.9 ± 6.4%. Total weight loss at 1 year was 38.8 ± 5.3% and at 5 years, 35.4 ± 4.9%. Postoperatively, a reduction in the intake of dairy products, red meat, deli meat products, shellfish, fried potatoes, sweets, rice, pasta, beer, and processed foods was observed. Vegetables, fruits, and legumes intake increased after surgery. In the first postoperative year, there was a slight intolerance to red meat, fruits, vegetables and legumes, dairy products, pasta, and rice that mostly disappeared 5 years after surgery. One year after sleeve gastrectomy, calibrated with a 50-French bougie, there are not important problems in the intake of foods a priori difficult to digest. These problems mostly disappeared 5 years after surgery. The decrease intake of other unhealthy foods is mostly based on the dietary counseling.

  9. Optimization of an effective growth medium for culturing probiotic bacteria for applications in strict vegetarian food products

    Directory of Open Access Journals (Sweden)

    Manju Pathak

    2012-10-01

    Full Text Available Background: This study aimed to modify de Man Rogosa Sharpe culture medium (termed MRS for selective cultivation of probiotics strain for the consumption by the strictly vegetarian human population. Vegetarian probiotic foods by definition must be free from all animal-derived ingredients. This not only includes the product ingredients but the probiotic inoculum as well. Probiotic starter cultures are traditionally grown and stored in media containing milk or meatderived ingredients. The presence of these ingredients makes the probiotic cell concentrates unsuitable for use in vegetarian products and thus creates the need for a growth medium which isfree from animal-derived ingredients. Present study investigated the growth of a strain of Lactobacillus lactis in MRS. The present invention relates in general to a bacterial culture media,and more specifically a complex microbial culture media, based on plant seed powder extract in place of animal extract for probiotic bacterial growth.Methods: Lactobacillus lactis, a probiotic, was grown in standard MRS culture medium as well as in our various test media (TM containing various vegetal source in place of beef extract, yeast extract and peptone as in case of MRS. The inoculated culture mediums were incubated at 37C for 72 hours and growth of probiotic is recorded at regular intervals. The growth was recorded as Colony Forming Units (CFUs.Results: The best growth of probiotic is observed in TM 2. TM 2 is the leguminous seed extract. Starter culture mediums for probiotics or other bacteria primarily contain protein from animal source. The possibility of using vegetal protein from TM 2 extract in place of peptones and meat extract for the nitrogen supplementation of culture media for the growth of lactic acid bacteria has been demonstrated.Functional Foods in Health and Disease 2012, 2(10:369-378 Conclusion: The absolute vegetarian culture medium containing TM 2 is better than standard MRS for the

  10. Lenient vs. strict rate control in patients with atrial fibrillation and heart failure: a post-hoc analysis of the RACE II study

    NARCIS (Netherlands)

    Mulder, Bart A.; van Veldhuisen, Dirk J.; Crijns, Harry J. G. M.; Tijssen, Jan G. P.; Hillege, Hans L.; Alings, Marco; Rienstra, Michiel; Groenveld, Hessel F.; van den Berg, Maarten P.; van Gelder, Isabelle C.

    2013-01-01

    It is unknown whether lenient rate control is an acceptable strategy in patients with AF and heart failure. We evaluated differences in outcome in patients with AF and heart failure treated with lenient or strict rate control. This post-hoc analysis of the RACE II trial included patients with an

  11. A Banach-Dieudonné theorem for the space of bounded continuous functions on a separable metric space with the strict topology

    NARCIS (Netherlands)

    Kraaij, R.C.

    2016-01-01

    Let X be a separable metric space and let β be the strict topology on the space of bounded continuous functions on X, which has the space of τ-additive Borel measures as a continuous dual space. We prove a Banach-Dieudonné type result for the space of bounded continuous functions equipped with β:

  12. The "high solubility" definition of the current FDA Guidance on Biopharmaceutical Classification System may be too strict for acidic drugs.

    Science.gov (United States)

    Yazdanian, Mehran; Briggs, Katherine; Jankovsky, Corinne; Hawi, Amale

    2004-02-01

    The purpose of this study was to assess if the definition of high solubility as proposed in the FDA Guidance on Biopharmaceutical Classification System (BCS) is too strict for highly permeable acidic drugs. The solubility and permeability values of 20 (18 acidic and 2 non-acidic) nonsteroidal anti-inflammatory drugs (NSAID) were determined. The NSAIDs were grouped into three different sets having acetic acid, propionic acid, or other acidic moieties such as fenamate, oxicam, and salicylate. Two nonacidic NSAIDs (celecoxib and rofecoxib) were also included for comparison purposes. Equilibrium solubility values were determined at pH 1.2, 5.0, 7.4, and in biorelevant media simulating fed intestinal fluid at pH 5.0. For a select number of acids, we also measured solubility values in media simulating gastric and fasted intestinal fluids. Permeability classification was established relative to that of reference drugs in the Caco-2 cell permeability model. Permeability coefficients for all drugs were measured at concentrations corresponding to the lowest and highest marketed dose strengths dissolved in 250 ml volume, and their potential interaction with cellular efflux pumps was investigated. All NSAIDs with different acidic functional groups were classified as highly permeable based on their Caco-2 cell permeability. Only ketorolac appeared to have a potential for interaction with cellular efflux pumps. Solubility classification was based on comparison of equilibrium solubility at pH 1.2, 5.0. and 7.4 relative to marketed dose strengths in 250 ml. The pKa values for the acidic NSAIDs studied were between 3.5 and 5.1. and, as expected, their solubility increased dramatically at pH 7.4 compared to pH 1.2. Only three NSAIDs, ketorolac, ketoprofen. and acetyl salicylic acid, meet the current criteria for high solubility over the entire pH range. However, with the exception of ibuprofen, oxaprozin, and mefenamic acid, the remaining compounds can be classified as Class I drugs

  13. An understanding of environmental concepts and issues among ...

    African Journals Online (AJOL)

    The major aim of this study is to assess the knowledge and understanding of Grade 10-12 students about selected environmental concepts and issues such as population, ozone layer, green house effect, and acid rain. Another aim of this study is to find out whether there is any difference between the knowledge and ...

  14. an understanding of environmental concepts and issues among

    African Journals Online (AJOL)

    environmental knowledge, attitudes and concern are also conflicting. As there is disagreement about the direction of relationships between different variables, therefore, there is a need to investigate the understanding of environmental concepts and issues among Grade 10-12 students from rural and urban schools.

  15. Trends and Issues in Distance Education: International Perspectives

    OpenAIRE

    EROGLU, Reviewed By Dr. Erhan

    2015-01-01

    Trends and Issues in Distance Education: International Perspectives Edited by Yusra Laila Visser, Lya Visser, Michael Simonsın, & Ray Amirault, 2005, United States of America: Information Age Publishing, Inc. pp. 315. ISBN 1-59311-212-2 Reviewed by Dr. Erhan EROGLU Anadolu University Eskisehir, TURKEY In this book, the terms of “distance education” has been discussed from different perspectives. The term “distance education” conjures up in many minds the image of modern, computer-enabled t...

  16. Safety Culture and Issue in the Malaysian Manufacturing Sector

    OpenAIRE

    Ali Danish; Yusof Yusri; Adam Anbia

    2017-01-01

    . This paper highlights the Safety culture and issue in the Malaysian Manufacturing Sector and emphasis the high occupational accidents due to lack of safety culture and non-compliance of the requirements of Occupational Safety and Health Act 1994. The aim of this study is to review the occupational accidents occurrence in the Malaysia workplace since 2012-2016. Malaysia aimed to reduce the occupational accidents, the results show by DOSH increase that Occupational Noise Induced Hearing Loss ...

  17. Trends and Issues in Distance Education: International Perspectives

    Directory of Open Access Journals (Sweden)

    Erhan EROGLU

    2006-04-01

    Full Text Available Trends and Issues in Distance Education: International Perspectives Edited by Yusra Laila Visser, Lya Visser, Michael Simonsın, & Ray Amirault, 2005, United States of America: Information Age Publishing, Inc. pp. 315. ISBN 1-59311-212-2 Reviewed by Dr. Erhan EROGLU Anadolu University Eskisehir, TURKEY In this book, the terms of “distance education” has been discussed from different perspectives. The term “distance education” conjures up in many minds the image of modern, computer-enabled technology that has blossomed in only the last twenty years. Many of the lessons learned over the last century of distance education research and practice have been implemented in a wide variety of distance education programs worldwide, from higher education online learning programs in the United States to rural, radio-based instructional programs in developing countries. Distance education is truly international discipline. While it is true that the term “distance education” has a universal definiton, local distance ducation experiences are often quite idiosyncratic. This idiosyncratic nature emerges from the need to integrate distance education within the constraints, oppurtunities, and realities of spesific cultural and geographic contexts. From these local distance education experiences, educators are developing new understandings of the broader field of distance education, including the trends and issues present in the field. ORGANIZATION OF THE SECTIONS This book has been organized by thematic content into four main sections. Each of these sections represents a unique level of analysis for trends and issues in distance education. Part I presents five distinct perspectives on the state of distance education and the trends and issues of the field. First perspective of five distinct perpectives is “a survey of progressive and conservative trends in education with implications for distance education practice.” Second perspective is

  18. Information technology research and development critical trends and issues

    CERN Document Server

    1985-01-01

    Information Technology Research and Development: Critical Trends and Issues is a report of the Office of Technology Assessment of the United States Government on the research and development in the area of information technology. The report discusses information technology research and development - its goals, nature, issues, and strategies; environment and its changes; the roles of the participants; and the health of its field. The book then goes on to four selected case studies in information technology: advanced computer architecture; fiber optic communications; software engineering; and ar

  19. Evaluation of a strict protocol approach in managing women with severe disease due to hypertension in pregnancy: A before and after study

    Directory of Open Access Journals (Sweden)

    Backer Fèbè

    2005-09-01

    Full Text Available Abstract Background To evaluate whether the introduction of a strict protocol based on the systemic evaluation of critically ill pregnant women with complications of hypertension affected the outcome of those women. Method Study group: Indigent South African women managed in the tertiary hospitals of the Pretoria Academic Complex. Since 1997 a standard definition of women with severe acute maternal morbidity (SAMM, also referred to as a Nearmiss, has been used in the Pretoria Academic Complex. All cases of SAMM and maternal deaths (MD were entered on the Maternal Morbidity and Mortality Audit System programme (MaMMAS. A comparison of outcome of severely ill women who had complications of hypertension in pregnancy was performed between 1997–1998 (original protocol and 2002–2003 (strict protocol. Data include women referred from outside the Pretoria Academic Complex area to the tertiary hospitals. Results Between 1997–1998 there were 79 women with SAMM and 18 maternal deaths due to complications of hypertension, compared with 91 women with SAMM and 13 maternal deaths in 2002–2003. The mortality index (MI declined from 18.6% to 12.5% (OR 0.62, 95% CI 0.27–1.45. Statistically significant fewer women had renal failure (RR 0.37, 95% CI 0.21 – 0.66 and cerebral complications (RR 0.52, 95%CI 0.34 – 0.81 during the second period, and liver dysfunction (RR 0.27 95%CI 0.06 – 1.25 tended to be lower. However, there tended to be an increase in the number of women, who had immune system failure (RR 4.2 95%CI 0.93 – 18.94 and respiratory failure (RR 1.42 95%CI 0.88 – 2.29 although it did not reach significance. Cardiac failure remained constant (RR 0.84 95%CI 0.54 – 1.30. Conclusion The strict protocol approach based on the systemic evaluation of severely ill pregnant women with complications of hypertension and an intensive, regular feedback mechanism has been associated with a reduction in the number of patients with renal failure and

  20. Strictly Limited Choice or Agency?

    DEFF Research Database (Denmark)

    Nell, Phillip Christopher; Puck, Jonas F.; Heidenreich, Stefan

    2015-01-01

    the external pressures are joined by strong firm-internal pressures. Our findings contribute to the scarce literature on firms’ political strategies in emerging markets. They also support recent criticism of institutional theory’s strong focus on isomorphism as the most important legitimacy-conveying mechanism......This article analyzes political strategies of MNC subsidiaries in emerging markets. We find that institutional pressures from public and private non-market actors in the emerging market lead to increased political activism. Furthermore, we find that these relationships become stronger, when....... We argue that the isomorphism-based either-or logic gives way to stronger agency of the subsidiary and to a logic of active negotiation and social construction of the subsidiary’s legitimacy in the emerging market. Our findings show support for this idea as political activism is one such way how...

  1. Mapping clinical journeys of Asian patients presenting to the Emergency Department with syncope: Strict adoption of international guidelines does not reduce hospitalisations.

    Science.gov (United States)

    Kojodjojo, Pipin; Boey, Elaine; Elangovan, Anita; Chen, Xianyi; Tan, Yuquan; Singh, Devinder; Yeo, Wee Tiong; Lim, Toon Wei; Seow, Swee Chong; Sim, Tiong Beng

    2016-09-01

    Limited data exists about management of syncope in Asia. The American College of Emergency Physicians (ACEP) and European Society of Cardiology (ESC) guidelines have defined the high-risk syncope patient. This study aims to determine the effectiveness of managing syncope in an Asian healthcare system and whether strict adherence of international guidelines would reduce hospitalizations. Patients attending the Emergency Department of a Singaporean tertiary hospital with syncope were identified. Clinical journeys of all patients were meticulously mapped by interrogation of a comprehensive electronic medical record system and linkages with national datasets. Primary endpoint was hospitalization. Secondary endpoints were recurrent syncope within 1year and all-cause mortality. Expected admission rates based on application of ACEP/ESC guidelines were calculated. 638 patients (43.8±22.4years, 49.0% male) presented with syncope. 48.9% were hospitalized for 2.9±3.2days. Yields of common investigations ranged from 0 to 11.5% and no diagnosis was reached in 51.5% of patients. Diuretics use (HR 5.1, p=0.01) and prior hospitalization for syncope (HR 6.9, psyncope. Over 2.8 SD 0.3years of follow-up, 40 deaths occurred. 24 patients who died within 12months of presentation were admitted or had a firm diagnosis upon discharge. Application of guidelines did not significantly reduce hospitalisations, with limited agreement which patients warrant admission. (Actual 376, ACEP 354, ESC 391 admissions, p=NS). Unstructured management of syncope results in nearly half of patients being admitted and substantial healthcare expenditures, yet with limited diagnostic yield. Strict adoption of ACEP or ESC guidelines does not reduce admissions. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  2. Deviation from strict homeostasis across multiple trophic levels in an invertebrate consumer assemblage exposed to high chronic phosphorus enrichment in a Neotropical stream.

    Science.gov (United States)

    Small, Gaston E; Pringle, Catherine M

    2010-03-01

    A central tenet of ecological stoichiometry is that consumer elemental composition is relatively independent of food resource nutrient content. Although the P content of some invertebrate consumer taxa can increase as a consequence of P-enriched food resources, little is known about how ecosystem nutrient loading can affect the elemental composition of entire consumer assemblages. Here we examine the potential for P enrichment across invertebrate consumer assemblages in response to chronic high P loading. We measured elemental ratios in invertebrate consumers and basal food resources in a series of streams in lowland Costa Rica that range widely in P levels (2-135 microg l(-1) soluble reactive P). Streams with high P levels receive natural long-term (over millennia) inputs of solute-rich groundwater while low-P streams do not receive these solute-rich groundwater inputs. P content of leaf litter and epilithon increased fourfold across the natural P gradient, exceeding basal resource P content values reported in the literature from other nutrient-rich streams. Invertebrate consumers from the high-P study stream were elevated twofold in P content across multiple taxonomic and functional feeding groups, including predators. Our results strongly support the hypothesis that elevated P content in consumers feeding on P-enriched food resources is a consequence of deviation from strict homeostasis. In contrast to prior studies, we found that between-stream variation in P content of a given taxon greatly exceeded within-stream variation among different taxa, suggesting that environment may be as important as phylogeny in controlling consumer stoichiometry. Relaxing the assumption of strict homeostasis presents challenges and opportunities for advancing our understanding of how nutrient limitation affects consumer growth. Moreover, our findings may provide a window into the future of how chronic anthropogenic nutrient loading can alter stoichiometric relationships in food

  3. Assessing the Land Subsidence Governance in Ningbo City: By a Close Study of the Building Collapse at the Strictly Protected Land Subsidence Area

    Science.gov (United States)

    Yu, Xia

    2016-04-01

    Ningbo is a coastal city in East China, its land subsidence problem was noticed in the 1960s. However, scientific management was insufficient at that time, so with the fast city development from the 1980s, groundwater was used by a large amount of small factories, and tall buildings were built on the land. It was in 2008, scientists predicted that if without doing anything to prevent the land from subsiding, the city will be covered by the East Sea in 2030. From then on, the local government implied several policies, such as shut down most of the groundwater pumping wells, set up a new authority to enhance the cooperation among different administration departments, and also set up a land subsidence monitoring center for the city. Recently, it is declared that a Stereo regulatory system of land subsidence governance has been achieved. However, in 2012, a 23-years old building in the city center collapsed. According to the City Planning 2009, this building is located just in the strictly protected land subsidence area. The experts, however, think that land subsidence is not the main reason, since there are many illegal changes to the building during the past 23 years. The aim of my research is to assess the land subsidence governance in Ningbo city. I studied the collapsed building, how it was built, what has changed after building, how the environment changed in this area, and how this area became the strictly protected land subsidence area, and what kind of protections have been made. Actually, during the case study I discuss the land subsidence governance design of Ningbo, and to see what practices and lessons we can learn from this case.

  4. TECHNICAL TRAINING SEMINAR: High Temperature Superconductors: Progress and Issues

    CERN Multimedia

    Davide Vitè

    2002-01-01

    Monday 24 June from 14:30 to 15:30 - Training Centre Auditorium - bldg. 593-11 High Temperature Superconductors: Progress and Issues Prof. Jan Evetts / UNIVERSITY OF CAMBRIDGE, Department of Materials Science and Metallurgy, UK Grappling with grain boundaries: Current transport processes in granular High Temperature Superconductors (HTS) The development of High Temperature Superconductors, seen from a materials scientist's point of view, is relevant to the superconductivity community at CERN: their possible high current applications can include high performance magnets for future accelerators. There is an urgent need to develop a quantitative description of HTS conductors in terms of their complex anisotropy, inhomogeneity and dimensionality. This is essential both for the practical specification of a conductor and for charting routes to conductor optimisation. The critical current, the n-value, dissipation and quenching characteristics are amongst most important parameters that make up an engineering specifi...

  5. Adaptive management of natural resources-framework and issues

    Science.gov (United States)

    Williams, B.K.

    2011-01-01

    Adaptive management, an approach for simultaneously managing and learning about natural resources, has been around for several decades. Interest in adaptive decision making has grown steadily over that time, and by now many in natural resources conservation claim that adaptive management is the approach they use in meeting their resource management responsibilities. Yet there remains considerable ambiguity about what adaptive management actually is, and how it is to be implemented by practitioners. The objective of this paper is to present a framework and conditions for adaptive decision making, and discuss some important challenges in its application. Adaptive management is described as a two-phase process of deliberative and iterative phases, which are implemented sequentially over the timeframe of an application. Key elements, processes, and issues in adaptive decision making are highlighted in terms of this framework. Special emphasis is given to the question of geographic scale, the difficulties presented by non-stationarity, and organizational challenges in implementing adaptive management. ?? 2010.

  6. CONSTRUCTION STATUS AND ISSUES OF THE SPALLATION NEUTRON SOURCE RING.

    Energy Technology Data Exchange (ETDEWEB)

    WEI,J.

    2004-07-05

    The Spallation Neutron Source (SNS) ring is designed to accumulate beam pulses of 1.5 x 10{sup 14} protons of 1 GeV kinetic energy at a repetition rate of 60 Hz [1]. At such beam intensity and power, key design challenges include control of beam loss and radio-activation, construction of high-quality large-aperture magnets and power supplies, design of robust injection and extraction systems, minimization of beam-coupling impedances, and mitigation of electron-cloud effects. This paper discusses the status of the ring systems with emphasis on technical challenges and issues, and presents future perspectives towards a next-generation high-intensity facility.

  7. Health benefit from decreasing exposure to heavy metals and metalloid after strict pollution control measures near a typical river basin area in China.

    Science.gov (United States)

    Cao, Suzhen; Duan, Xiaoli; Ma, Yingqun; Zhao, Xiuge; Qin, Yanwen; Liu, Yan; Li, Sai; Zheng, Binghui; Wei, Fusheng

    2017-10-01

    The metal(loid) pollution still is a great concern due to the effects from urbanization and industrialization. While, the health risks from the toxic metal(loid)s could decrease if strict pollution control measures were adopted. However, few studies to date investigate the health risks of heavy metal(loid)s in a systematic river basin for the dependent residents, after taking pollution control measures. Thus, the contents of metal(loid)s (Cu, Pb, Zn, Cd, Mn, As) in surface water along a typical river basin were investigated in this study, and the potential non-carcinogenic and carcinogenic health risks posed to the residents were assessed. Although the soluble contents of Cu, Pb, Zn and Cd exceeded the respective thresholds in two sites located downstream the mine area, they were greatly decreased in comparison with previous contamination levels, and the soluble concentrations of all the metal(loid)s were within the relevant thresholds in the sites far away from the mining area. Moreover, the closer to the mining area, the higher the pollution levels of metal(loid)s. The total hazard index for non-carcinogenic risks of metal(loid)s were basically lower than the threshold (1) for the local population. Whereas, although the content of metal(loid)s were low (such as As), they could pose relative higher non-carcinogenic health risks. The result illustrated that pollution levels, toxicity of the contaminants and exposure behavior patterns all could contribute to the potential detrimental health risks. Additionally, the non-carcinogenic and carcinogenic risks from ingestion exposure were ∼2-∼4 orders of magnitude higher than those from dermal contact. The total carcinogenic risks were basically lower than the maximum tolerable levels (1.0 × 10 -4 ), indicating carcinogenic risks from most areas of the river could also be accepted. Among different population groups, heavy metal(loid)s posed relative higher non-carcinogenic and carcinogenic risks to the children in

  8. The cost of emergency obstetric care: concepts and issues.

    Science.gov (United States)

    Desai, J

    2003-04-01

    Emergency obstetric care (EmOC), like any health intervention, requires resources, and resources are almost always limited. This forces decision makers to take into account the costs (and effectiveness) of EmOC provision and compare them with the costs (and effectiveness) of other health interventions. This is not inordinately complicated, but it does require paying attention to the fact that EmOC services require different types of inputs and are produced in facilities that also provide other health care services. This paper discusses the basic concepts underlying the costing of EmOC services, and the essential issues one must take into account while assessing the cost-effectiveness of EmOC interventions. A definition of EmOC provision cost is offered and then explained by progressively refining a simple measure of expenditures on all that is used to provide EmOC services. Thereupon the process of collecting cost data and calculating costs is outlined using a simple spreadsheet format, and issues related to the analysis of costs and cost-effectiveness are discussed.

  9. Safety Culture and Issue in the Malaysian Manufacturing Sector

    Directory of Open Access Journals (Sweden)

    Ali Danish

    2017-01-01

    Full Text Available . This paper highlights the Safety culture and issue in the Malaysian Manufacturing Sector and emphasis the high occupational accidents due to lack of safety culture and non-compliance of the requirements of Occupational Safety and Health Act 1994. The aim of this study is to review the occupational accidents occurrence in the Malaysia workplace since 2012-2016. Malaysia aimed to reduce the occupational accidents, the results show by DOSH increase that Occupational Noise Induced Hearing Loss 83.7%, occupational musculoskeletal diseases, 4.4% and occupational lung diseases 2.3%. But the as per the record from DOSH that in last 5-Years, the increment in the fatal accidents by Average 26%, Permanent Disability by Average 71% and Non-Permanent Disability by 64 % are investigated only in Manufacturing Industries. The government must show their high interest on such a vulnerable employees to accomplish the above aim. This step will be helpful for planning to reduce the accidents in workplaces and it will also detect the prevention for the future accidents.

  10. When is it acceptable to kill a strictly protected carnivore? Exploring the legal constraints on wildlife management within Europe’s Bern Convention

    Directory of Open Access Journals (Sweden)

    John D. C. Linnell

    2017-09-01

    Full Text Available As wolf populations expand across Europe, many countries face challenges in finding ways to address the concerns of some elements among the rural stakeholders who are being asked to share their landscapes with wolves for the first time in several generations. In these recovery landscapes, wolves are associated with a wide range of conflicts that include economic, psychological, perceptional, social, cultural and political dimensions. A recurring demand concerns the desire to introduce the use of carefully regulated lethal control of wolves, through either culling by state employees or hunting conducted by rural hunters. Introducing such measures can be very controversial, and many critics challenge their legality under the international wildlife conservation instruments that have nurtured wolf recovery. We evaluate this issue for the case of wolves in Norway, which are strictly protected under the Bern Convention. Drawing on the latest results of social science research, we present the multiple lines of argumentation that are often used to justify killing wolves and relate these to the criteria for exceptions that exist under the Bern Convention. We conclude that while the Convention provides apparent scope for allowing the killing of wolves as a means to address conflicts, this must be clearly justified and proportional to the conservation status of wolves so as to not endanger their recovery.

  11. The Strictly Conserved Arg-321 Residue in the Active Site of Escherichia coli Topoisomerase I Plays a Critical Role in DNA Rejoining*

    Science.gov (United States)

    Narula, Gagandeep; Annamalai, Thirunavukkarasu; Aedo, Sandra; Cheng, Bokun; Sorokin, Elena; Wong, Agnes; Tse-Dinh, Yuk-Ching

    2011-01-01

    The strictly conserved arginine residue proximal to the active site tyrosine of type IA topoisomerases is required for the relaxation of supercoiled DNA and was hypothesized to be required for positioning of the scissile phosphate for DNA cleavage to take place. Mutants of recombinant Yersinia pestis topoisomerase I with hydrophobic substitutions at this position were found in genetic screening to exhibit a dominant lethal phenotype, resulting in drastic loss in Escherichia coli viability when overexpressed. In depth biochemical analysis of E. coli topoisomerase I with the corresponding Arg-321 mutation showed that DNA cleavage can still take place in the absence of this arginine function if Mg2+ is present to enhance the interaction of the enzyme with the scissile phosphate. However, DNA rejoining is inhibited in the absence of this conserved arginine, resulting in accumulation of the cleaved covalent intermediate and loss of relaxation activity. These new experimental results demonstrate that catalysis of DNA rejoining by type IA topoisomerases has a more stringent requirement than DNA cleavage. In addition to the divalent metal ions, the side chain of this arginine residue is required for the precise positioning of the phosphotyrosine linkage for nucleophilic attack by the 3′-OH end to result in DNA rejoining. Small molecules that can interfere or distort the enzyme-DNA interactions required for DNA rejoining by bacterial type IA topoisomerases could be developed into novel antibacterial drugs. PMID:21478161

  12. Modeling the adsorption of hydrogen, sodium, chloride and phthalate on goethite using a strict charge-neutral ion-exchange theory

    Science.gov (United States)

    Ndu, Udonna

    2017-01-01

    Simultaneous adsorption modeling of four ions was predicted with a strict net charge-neutral ion-exchange theory and its corresponding equilibrium and mass balance equations. An important key to the success of this approach was the proper collection of all the data, particularly the proton adsorption data, and the inclusion of variable concentrations of conjugate ions from the experimental pH adjustments. Using IExFit software, the ion-exchange model used here predicted the competitive retention of several ions on goethite by assuming that the co-adsorption or desorption of all ions occurred in the correct stoichiometries needed to maintain electroneutrality. This approach also revealed that the retention strength of Cl− ions on goethite increases in the presence of phthalate ions. That is, an anion-anion enhancement effect was observed. The retention of Cl− ions was much weaker than phthalate ions, and this also resulted in a higher sensitivity of the Cl− ions toward minor variations in the surface reactivity. The proposed model uses four goethite surface sites. The drop in retention of phthalate ions at low pH was fully described here as resulting from competitive Cl− reactions, which were introduced in increasing concentrations into the matrix as the conjugate base to the acid added to lower the pH. PMID:28464020

  13. Przewalski’ s Horse ( Equus ferus przewalskii Re-intr oduction in the Great Gobi B Strictly Protected Area: from Species to Ecosystem Conservation

    Directory of Open Access Journals (Sweden)

    P. Kaczensky

    2007-05-01

    Full Text Available The Przewalski’s horse ( Equus ferus przewalskii Po ljakov , 1881, or “T akhi” in Mongolian, became extinct in the wild by the mid 1960’ s. The last recorded sightings of Przewalski’s horses occurred in the Dzungarian Gobi desert in SW Mo ngolia, today’s Great Gobi B Strictly Protected Area (SP A. A re - introduction program was initiated in 1992 and the fi rs t group of captive-born Przewalski’s horses was airlifted to the SPA. Given the logistical challenges associated with such a venture, the initial project focus has been on transport logistics and the well-being of the re-introduced horses. Tod ay, conservation efforts are spread over the entire protected area. Present day ef forts include other mammals, vegetation and the local people. Due to its important symbolic value in Mongolian culture, the Przewalski’ s horse became an important fl agship species for the protected area’s conservation and management.

  14. Asymmetric reduction of ketopantolactone using a strictly (R)-stereoselective carbonyl reductase through efficient NADPH regeneration and the substrate constant-feeding strategy.

    Science.gov (United States)

    Zhao, Man; Gao, Liang; Zhang, Li; Bai, Yanbin; Chen, Liang; Yu, Meilan; Cheng, Feng; Sun, Jie; Wang, Zhao; Ying, Xiangxian

    2017-11-01

    To characterize a recombinant carbonyl reductase from Saccharomyces cerevisiae (SceCPR1) and explore its use in asymmetric synthesis of (R)-pantolactone [(R)-PL]. The NADPH-dependent SceCPR1 exhibited strict (R)-enantioselectivity and high activity in the asymmetric reduction of ketopantolactone (KPL) to (R)-PL. Escherichia coli, coexpressing SceCPR1 and glucose dehydrogenase from Exiguobacterium sibiricum (EsGDH), was constructed to fulfill efficient NADPH regeneration. During the whole-cell catalyzed asymmetric reduction of KPL, the spontaneous hydrolysis of KPL significantly affected the yield of (R)-PL, which was effectively alleviated by the employment of the substrate constant-feeding strategy. The established whole-cell bioreduction for 6 h afforded 458 mM (R)-PL with the enantiomeric excess value of >99.9% and the yield of 91.6%. Escherichia coli coexpressing SceCPR1 and EsGDH efficiently catalyzed the asymmetric synthesis of (R)-PL through the substrate constant-feeding strategy.

  15. 31 CFR 356.0 - What authority does the Treasury have to sell and issue securities?

    Science.gov (United States)

    2010-07-01

    ... to sell and issue securities? 356.0 Section 356.0 Money and Finance: Treasury Regulations Relating to... sell and issue securities? Chapter 31 of Title 31 of the United States Code authorizes the Secretary of... AND ISSUE OF MARKETABLE BOOK-ENTRY TREASURY BILLS, NOTES, AND BONDS (DEPARTMENT OF THE TREASURY...

  16. Enrichment of HLA Types and Single-Nucleotide Polymorphism Associated With Non-progression in a Strictly Defined Cohort of HIV-1 Controllers

    Directory of Open Access Journals (Sweden)

    Samantha J. Westrop

    2017-06-01

    Full Text Available HIV-1 controllers (HIC are extremely rare patients with the ability to control viral replication, maintain unchanging CD4 T-cell count, and evade disease progression for extensive periods of time, in the absence of antiretroviral therapy. In order to establish the representation of key genetic correlates of atypical disease progression within a cohort of HIV-1+ individuals who control viral replication, we examine four-digit resolution HLA type and single-nucleotide polymorphisms (SNP previously identified to be correlated to non-progressive infection, in strictly defined HIC. Clinical histories were examined to identify patients exhibiting HIC status. Genomic DNA was extracted, and high definition HLA typing and genome-wide SNP analysis was performed. Data were compared with frequencies of SNP in European long-term non-progressors (LTNP and primary infection cohorts. HLA-B alleles associated with atypical disease progression were at very high frequencies in the group of five HIC studied. All four HIC of European ancestry were HLA-B*57+ and half were also HLA-B*27+. All HIC, including one of self-reported African ethnicity, had the HLA-Cw*0602 allele, and the HLA-DQ9 allele was present only in HIC of European ancestry. A median 95% of the top 19 SNP known to be associated with LTNP status was observed in European HIC (range 78–100%; 17/19 of the SNP considered mapped to chromosome 6 in the HLA region, whereas 2/19 mapped to chromosome 8. The HIC investigated here demonstrated high enrichment of HLA types and SNP previously associated with long-term non-progression. These findings suggest that the extreme non-progressive phenotype considered here is associated with a genetic signature characterized by a single-genetic unit centered around the HLA-B*57 haplotype and the possible additive effect of HLA-B*27.

  17. Hepatitis A in Puglia (South Italy) after 10 years of universal vaccination: need for strict monitoring and catch-up vaccination

    Science.gov (United States)

    2012-01-01

    Background Raw seafood consumption was identified as the major risk factor for hepatitis A during the large epidemic of 1996 and 1997 in Puglia (South Italy). In Puglia, vaccination for toddlers and preadolescents has been recommended since 1998. The aim of the study was to evaluate the incidence, seroprevalence, molecular epidemiology, and environmental circulation of hepatitis A virus (HAV) in Puglia more than ten years after the introduction of anti-HAV vaccination in the regional immunization program. Methods Data on the incidence of acute hepatitis A in Puglia were analyzed. Characteristics and risk factors of 97 acute hepatitis A cases occurring in 2008–2009 were analyzed. Serum samples from 868 individuals aged 0 to 40 years were tested for anti-HAV antibodies. Fecal samples from 49 hepatitis A cases were analyzed by sequence analysis in the VP1/P2A region. In 2008, 203 mussel samples and 202 water samples from artesian wells were tested for HAV-RNA. Results Between 1998 and 2009, the incidence of acute hepatitis A declined from 14.8 to 0.8 per 100,000. The most frequent risk factors reported by cases in 2008–2009 were shellfish consumption (85%) and travel outside of Puglia or Italy (26%). Seroepidemiologic survey revealed high susceptibility to HAV in children and adults up to age 30 (65%-70%). None of the mussel or water samples were HAV-positive. Phylogenetic analysis revealed co-circulation of subtypes IA (74%) and IB (26%) and clustering of strains with strains from Germany and France, and those previously circulating in Puglia. Conclusion Vaccination and improved sanitation reduced the incidence of hepatitis A. Strict monitoring and improved vaccination coverage are needed to prevent disease resurgence. PMID:23098290

  18. Agronomic traits and deoxynivalenol contamination of two tetraploid wheat species (Triticum turgidum spp. durum, Triticum turgidum spp. turanicum grown strictly under low input conditions

    Directory of Open Access Journals (Sweden)

    Giovanni Dinelli

    2014-09-01

    Full Text Available An evaluation of the agronomic performance of two tetraploid wheat varieties (Triticum turgidum spp. durum, Claudio; Triticum turgidum spp. turanicum, Kamut® grown strictly under low input conditions was carried out over three consecutive cropping years. The study reported grain yield values ranging from 1.8 to 2.6 t ha-1. Productivity showed to be primarily affected by environmental conditions, while no differences were observed between the two genotypes. The study of the yield components highlighted that the durum wheat variety had a higher plant density than Kamut®, but this discrepancy was offset by a greater number of kernels per spike and the kernel weight of khorasan wheat. The investigated wheat genotypes were also analysed to assess the mycotoxin (DON levels of wholegrain semolina and the efficiency of cleaning treatments to reduce contamination. Results showed that both wheat varieties had a good hygienic and sanitary quality with a DON content ranging from 0.35 to 1.31 mg kg-1, which was lower than the maximum acceptable level set by the European regulation at 1.75 mg kg-1. In addition, our research work investigated the effects of premilling cleaning procedures, such as water washing and brushing, on mycotoxin levels, which yielded interesting results in terms of decontamination efficiency. These methods were particularly efficient with Kamut® semolina (46-93% DON reduction, suggesting that mycotoxins accumulate in this variety at more superficial levels than in the durum wheat variety. On the whole, our study provided additional knowledge on the traits to be further improved to respond to low input requirements and to enhance the potential adaptability of wheat genotypes to organic agriculture. Our results emphasized the need to develop wheat varieties that can provide adequate performance without high levels of nitrogen inputs by selecting specific traits, such as kernel weight, spike length and kernel/spike. This may help

  19. Altered Na+ transport after an intracellular alpha-subunit deletion reveals strict external sequential release of Na+ from the Na/K pump.

    Science.gov (United States)

    Yaragatupalli, Siddhartha; Olivera, J Fernando; Gatto, Craig; Artigas, Pablo

    2009-09-08

    The Na/K pump actively exports 3 Na(+) in exchange for 2 K(+) across the plasmalemma of animal cells. As in other P-type ATPases, pump function is more effective when the relative affinity for transported ions is altered as the ion binding sites alternate between opposite sides of the membrane. Deletion of the five C-terminal residues from the alpha-subunit diminishes internal Na(+) (Na(i)(+)) affinity approximately 25-fold [Morth et al. (2007) Nature 450:1043-1049]. Because external Na(+) (Na(o)(+)) binding is voltage-dependent, we studied the reactions involving this process by using two-electrode and inside-out patch voltage clamp in normal and truncated (DeltaKESYY) Xenopus-alpha1 pumps expressed in oocytes. We observed that DeltaKESYY (i) decreased both Na(o)(+) and Na(i)(+) apparent affinities in the absence of K(o)(+), and (ii) did not affect apparent Na(o)(+) affinity at high K(o)(+). These results support a model of strict sequential external release of Na(+) ions, where the Na(+)-exclusive site releases Na(+) before the sites shared with K(+) and the DeltaKESYY deletion only reduces Na(o)(+) affinity at the shared sites. Moreover, at nonsaturating K(o)(+), DeltaKESYY induced an inward flow of Na(+) through Na/K pumps at negative potentials. Guanidinium(+) can also permeate truncated pumps, whereas N-methyl-D-glucamine cannot. Because guanidinium(o)(+) can also traverse normal Na/K pumps in the absence of both Na(o)(+) and K(o)(+) and can also inhibit Na/K pump currents in a Na(+)-like voltage-dependent manner, we conclude that the normal pathway transited by the first externally released Na(+) is large enough to accommodate guanidinium(+).

  20. Lebetimonas natsushimae sp. nov., a novel strictly anaerobic, moderately thermophilic chemoautotroph isolated from a deep-sea hydrothermal vent polychaete nest in the Mid-Okinawa Trough.

    Science.gov (United States)

    Nagata, Ryousuke; Takaki, Yoshihiro; Tame, Akihiro; Nunoura, Takuro; Muto, Hisashi; Mino, Sayaka; Sawayama, Shigeki; Takai, Ken; Nakagawa, Satoshi

    2017-09-01

    A moderately thermophilic, strictly anaerobic, chemoautotrophic bacterium, designated strain HS1857 T , was isolated from a deep-sea hydrothermal vent at the Noho site in the Mid-Okinawa Trough. Strain HS1857 T grew between 35 and 63°C (optimum 55°C), in the presence of 10-55gl -1 NaCl (optimum 25gl -1 ), and pH 5.5-7.1 (optimum 6.4). Growth occurred with molecular hydrogen as the electron donor and elemental sulfur, nitrate, or selenate as the electron acceptors. Formate could serve as an alternative electron donor with nitrate as an electron acceptor. During growth with nitrate as the electron acceptor, strain HS1857 T produced ammonium and formed a biofilm. CO 2 was utilized as the sole carbon source. The G+C content of the genomic DNA was 33.2mol%. Phylogenetic analysis of the 16S rRNA gene sequence indicated that strain HS1857 T is a member of the order Nautiliales, showing a sequence similarity of 95.0% with Lebetimonas acidiphila Pd55 T . The fatty acid composition was similar to that of L. acidiphila, which was dominated by C 18:0 (47.0%) and C 18:1 (23.7%). Based on the genomic, chemotaxonomic, phenotypic characteristics, the name Lebetimonas natsushimae sp. nov., is proposed. The type strain is HS1857 T (=NBRC 112478 T =DSM 104102 T ). Copyright © 2017 Elsevier GmbH. All rights reserved.

  1. Fuel Cycle Externalities: Analytical Methods and Issues, Report 2

    International Nuclear Information System (INIS)

    Barnthouse, L.W.; Cada, G.F.; Cheng, M.-D.; Easterly, C.E.; Kroodsma, R.L.; Lee, R.; Shriner, D.S.; Tolbert, V.R.; Turner, R.S.

    1994-01-01

    that also have not been fully addressed. This document contains two types of papers that seek to fill part of this void. Some of the papers describe analytical methods that can be applied to one of the five steps of the damage function approach. The other papers discuss some of the complex issues that arise in trying to estimate externalities. This report, the second in a series of eight reports, is part of a joint study by the U.S. Department of Energy (DOE) and the Commission of the European Communities (EC)* on the externalities of fuel cycles. Most of the papers in this report were originally written as working papers during the initial phases of this study. The papers provide descriptions of the (non-radiological) atmospheric dispersion modeling that the study uses; reviews much of the relevant literature on ecological and health effects, and on the economic valuation of those impacts; contains several papers on some of the more complex and contentious issues in estimating externalities; and describes a method for depicting the quality of scientific information that a study uses. The analytical methods and issues that this report discusses generally pertain to more than one of the fuel cycles, though not necessarily to all of them. The report is divided into six parts, each one focusing on a different subject area

  2. Estimating Fuel Cycle Externalities: Analytical Methods and Issues, Report 2

    Energy Technology Data Exchange (ETDEWEB)

    Barnthouse, L.W.; Cada, G.F.; Cheng, M.-D.; Easterly, C.E.; Kroodsma, R.L.; Lee, R.; Shriner, D.S.; Tolbert, V.R.; Turner, R.S.

    1994-07-01

    of complex issues that also have not been fully addressed. This document contains two types of papers that seek to fill part of this void. Some of the papers describe analytical methods that can be applied to one of the five steps of the damage function approach. The other papers discuss some of the complex issues that arise in trying to estimate externalities. This report, the second in a series of eight reports, is part of a joint study by the U.S. Department of Energy (DOE) and the Commission of the European Communities (EC)* on the externalities of fuel cycles. Most of the papers in this report were originally written as working papers during the initial phases of this study. The papers provide descriptions of the (non-radiological) atmospheric dispersion modeling that the study uses; reviews much of the relevant literature on ecological and health effects, and on the economic valuation of those impacts; contains several papers on some of the more complex and contentious issues in estimating externalities; and describes a method for depicting the quality of scientific information that a study uses. The analytical methods and issues that this report discusses generally pertain to more than one of the fuel cycles, though not necessarily to all of them. The report is divided into six parts, each one focusing on a different subject area.

  3. On combination of strict Bayesian principles with model reduction technique or how stochastic model calibration can become feasible for large-scale applications

    Science.gov (United States)

    Oladyshkin, S.; Schroeder, P.; Class, H.; Nowak, W.

    2013-12-01

    Predicting underground carbon dioxide (CO2) storage represents a challenging problem in a complex dynamic system. Due to lacking information about reservoir parameters, quantification of uncertainties may become the dominant question in risk assessment. Calibration on past observed data from pilot-scale test injection can improve the predictive power of the involved geological, flow, and transport models. The current work performs history matching to pressure time series from a pilot storage site operated in Europe, maintained during an injection period. Simulation of compressible two-phase flow and transport (CO2/brine) in the considered site is computationally very demanding, requiring about 12 days of CPU time for an individual model run. For that reason, brute-force approaches for calibration are not feasible. In the current work, we explore an advanced framework for history matching based on the arbitrary polynomial chaos expansion (aPC) and strict Bayesian principles. The aPC [1] offers a drastic but accurate stochastic model reduction. Unlike many previous chaos expansions, it can handle arbitrary probability distribution shapes of uncertain parameters, and can therefore handle directly the statistical information appearing during the matching procedure. We capture the dependence of model output on these multipliers with the expansion-based reduced model. In our study we keep the spatial heterogeneity suggested by geophysical methods, but consider uncertainty in the magnitude of permeability trough zone-wise permeability multipliers. Next combined the aPC with Bootstrap filtering (a brute-force but fully accurate Bayesian updating mechanism) in order to perform the matching. In comparison to (Ensemble) Kalman Filters, our method accounts for higher-order statistical moments and for the non-linearity of both the forward model and the inversion, and thus allows a rigorous quantification of calibrated model uncertainty. The usually high computational costs of

  4. Sorption-induced reversible oxidation of Fe(2) at the smectite/water interface under strictly anoxic conditions. A Moessbauer spectroscopy study

    Energy Technology Data Exchange (ETDEWEB)

    Gehin, A.; Charlet, L. [Laboratoire de Geophysique Interne et Tectonophysique (LGIT), Universite de Grenoble, 38 - Grenoble (France); Gehin, A. [Agence Nationale pour la Gestion des Dechets Radioactifs, ANDRA, 92 - Chatenay Malabry (France); Greneche, J.M. [Laboratoire de Physique de l' Etat Condense, UMR-CNRS 6087, 72 - Le Mans (France); Brendle, J. [Universite de Haute Alsace, Lab. des Materiaux Mineraux (LMM), 68 - Mulhouse (France); Rancourt, D.G. [Ottawa Univ., Dept. of Physics, Ontario (Canada)

    2005-07-01

    Previous studies of Fe(II) sorption onto montmorillonite have been performed with the mineral extracted from the MX80 bentonite. These studies have shown that Fe(II) can be sorbed onto clay minerals in cation exchange position. The affinity of montmorillonite for Fe(II) and Ca(II) is identical. Fe(II) may also be specifically adsorbed onto montmorillonite clay edges. Moessbauer spectroscopy confirmed the high affinity of clay surfaces for Fe(II) sorption and showed that this sorption is mainly due to a two step mechanism: Fe(II) specific adsorption, followed by oxidation of the Fe(II) sorbed. The identification of the oxidizing agent was prohibited due to the complex chemistry of the natural MX80 montmorillonite. Thus, synthetic iron-free montmorillonite was used (chemical formula: Ca{sub 0.3} (A{sub 1.4}Mg{sub 0.6}) (Si{sub 4}) O{sub 10}(OH){sub 2} ). {sup 57}Fe(II) sorption experiments were conducted in a N{sub 2} atmosphere gloves-box, in strictly anoxic conditions. Solid samples were synthesized in order to confirm the clay high affinity for Fe(II), in absence of structural oxidant, and to have a better comprehension of the sorption mechanism. Moessbauer spectra were recorded for each sample. Whereas no Fe(III) is detected in solution as pH was increased and then, a significant amount of surface sorbed Fe(III) was found to be reversibly produced, which amounts for 0-3% of total Fe in the pre-sorption edge acid region, up to 7% of total Fe when all Fe is sorbed in the neutral to alkaline pH range. From pH {approx_equal} 2 to pH {approx_equal} 7, a sorption edge plateau is observed. In this plateau, the sorbed-Fe(III)/sorbed-Fe ratio increases with pH, up to 45% at pH 7. Moessbauer spectra comparison with ferrous hydroxide, synthesized in the same redox conditions at higher pH, show that this oxidation can not be due to the trace amounts Oz in the suspension. The Moessbauer spectra components of both Fe(II) and Fe(III) appears as paramagnetic doublets: iron has

  5. 78 FR 60998 - Proposed Collection: Information Collection Surrounding the Sale and Issue of Marketable Book...

    Science.gov (United States)

    2013-10-02

    ... Collection Surrounding the Sale and Issue of Marketable Book-Entry Securities ACTION: Notice and request for... Department of the Treasury is soliciting comments concerning the Sale and Issue of Marketable Book-Entry... Marketable Book-Entry Securities. OMB Number: 1535-0112. Abstract: The information is requested to ensure...

  6. Navy Lasers, Railgun, and Hypervelocity Projectile: Background and Issues for Congress

    Science.gov (United States)

    2017-03-17

    Navy Lasers , Railgun, and Hypervelocity Projectile: Background and Issues for Congress Ronald O’Rourke Specialist in Naval Affairs March 17...2017 Congressional Research Service 7-5700 www.crs.gov R44175 Navy Lasers , Railgun, and Hypervelocity Projectile: Background and Issues for...surface ships to defend themselves against enemy missiles—solid state lasers (SSLs), the electromagnetic railgun (EMRG), and the hypervelocity

  7. Navy Lasers, Railgun, and Hypervelocity Projectile: Background and Issues for Congress

    Science.gov (United States)

    2016-10-21

    and causing thermal damage to their interiors. Lasers can also be used to “ dazzle ” (i.e., interfere with) electro-optical sensors on a boat or...Navy Lasers , Railgun, and Hypervelocity Projectile: Background and Issues for Congress Ronald O’Rourke Specialist in Naval Affairs October...21, 2016 Congressional Research Service 7-5700 www.crs.gov R44175 Navy Lasers , Railgun, and Hypervelocity Projectile: Background and Issues for

  8. Comments on the thesis of Schopenhauer's psicology: "The strict distincttion between knowledge and will and the priority of the first one" from Complementos ao mundo como vontade e representação

    Directory of Open Access Journals (Sweden)

    André Luiz Simões Pedreira

    2015-04-01

    Full Text Available Our paper aims to review the theories of the psychology of Schopenhauer, namely, "strict distinction between will and knowledge and the primacy of the first", contained in the Book Room ons of The World as Will and Representation, in Chapter 41, entitled "on Death and its relationship with the indestructible character of our being itself." The review aimed to present some of the passages ons that ensure the distinction between Will and Intellect in order to provide data to avoid confusion, that many readers Schopenhauer are affected, the Will to confuse metaphysics with its phenomenon, namely the human will.

  9. Simple and versatile turbidimetric monitoring of bacterial growth in liquid cultures using a customized 3D printed culture tube holder and a miniaturized spectrophotometer: application to facultative and strictly anaerobic bacteria

    Directory of Open Access Journals (Sweden)

    Margarida R. G. Maia

    2016-08-01

    Full Text Available Here we introduce a novel strategy for turbidimetric monitoring of bacterial growth in liquid culture. The instrumentation comprises a light source, a customized 3D printed culture tube holder and a miniaturized spectrophotometer, connected through optical cables. Due to its small footprint and the possibility to operate with external light, bacterial growth was directly monitored from culture tubes in a simple and versatile fashion. This new portable measurement technique was used to monitor the growth of facultative (Escherichia coli ATCC/25922, and Staphylococcus aureus ATCC/29213 and strictly (Butyrivibrio fibrisolvens JW11, Butyrivibrio proteoclasticus P18, and Propionibacterium acnes DSMZ 1897 anaerobic bacteria. For E. coli and S. aureus, the growth rates calculated from normalized optical density values were compared with those ones obtained using a benchtop spectrophotometer without significant differences (P = 0.256. For the strictly anaerobic species, a high precision (RSD < 3.5% was observed between replicates up to 48 h. Regarding its potential for customization, this manifold could accommodate further developments for customized turbidimetric monitoring, such as the use of light-emitting diodes as a light source or flow cells.

  10. Simple and Versatile Turbidimetric Monitoring of Bacterial Growth in Liquid Cultures Using a Customized 3D Printed Culture Tube Holder and a Miniaturized Spectrophotometer: Application to Facultative and Strictly Anaerobic Bacteria.

    Science.gov (United States)

    Maia, Margarida R G; Marques, Sara; Cabrita, Ana R J; Wallace, R John; Thompson, Gertrude; Fonseca, António J M; Oliveira, Hugo M

    2016-01-01

    Here we introduce a novel strategy for turbidimetric monitoring of bacterial growth in liquid culture. The instrumentation comprises a light source, a customized 3D printed culture tube holder and a miniaturized spectrophotometer, connected through optical cables. Due to its small footprint and the possibility to operate with external light, bacterial growth was directly monitored from culture tubes in a simple and versatile fashion. This new portable measurement technique was used to monitor the growth of facultative (Escherichia coli ATCC/25922, and Staphylococcus aureus ATCC/29213) and strictly (Butyrivibrio fibrisolvens JW11, Butyrivibrio proteoclasticus P18, and Propionibacterium acnes DSMZ 1897) anaerobic bacteria. For E. coli and S. aureus, the growth rates calculated from normalized optical density values were compared with those ones obtained using a benchtop spectrophotometer without significant differences (P = 0.256). For the strictly anaerobic species, a high precision (relative standard deviation < 3.5%) was observed between replicates up to 48 h. Regarding its potential for customization, this manifold could accommodate further developments for customized turbidimetric monitoring, such as the use of light-emitting diodes as a light source or flow cells.

  11. The Black Man on Film: Racial Stereotyping. Hayden Film Attitudes and Issues Series.

    Science.gov (United States)

    Maynard, Richard A.

    Motion pictures have long been recognized as a mirror of society's values and attitudes, and for motivational and impression-making impact they are unsurpassed. The Hayden Film Attitudes and Issues Series is based on the teacher's source book, the Celluloid Curriculum: How to Use Movies in the Classroom. This series presents written sources…

  12. Information Security Trends and Issues in the Moodle E-Learning Platform: An Ethnographic Content Analysis

    Science.gov (United States)

    Schultz, Christopher

    2012-01-01

    Empirical research on information security trends and practices in e-learning is scarce. Many articles that have been published apply basic information security concepts to e-learning and list potential threats or propose frameworks for classifying threats. The purpose of this research is to identify, categorize and understand trends and issues in…

  13. A Study of Current Trends and Issues Related to Technical/Engineering Design Graphics.

    Science.gov (United States)

    Clark, Aaron C.; Scales Alice

    2000-01-01

    Presents results from a survey of engineering design graphics educators who responded to questions related to current trends and issues in the profession of graphics education. Concludes that there is a clear trend in institutions towards the teaching of constraint-based modeling and computer-aided manufacturing. (Author/YDS)

  14. Navy Ford (CVN-78) Class Aircraft Carrier Program: Background and Issues for Congress

    Science.gov (United States)

    2015-12-17

    construction of the Ford class aircraft carriers designated CVN–80 and CVN–81 in economic order quantities when cost savings are achievable. (2) LIABILITY ...Navy Ford (CVN-78) Class Aircraft Carrier Program: Background and Issues for Congress Ronald O’Rourke Specialist in Naval Affairs December 17...

  15. Navy Virginia (SSN-774) Class Attack Submarine Procurement: Background and Issues for Congress

    Science.gov (United States)

    2016-02-12

    Navy Virginia (SSN-774) Class Attack Submarine Procurement: Background and Issues for Congress Ronald O’Rourke Specialist in Naval Affairs......Congressional Research Service Summary The Navy has been procuring Virginia (SSN-774) class nuclear-powered attack submarines since FY1998. The two

  16. Navy Virginia (SSN 774) Class Attack Submarine Procurement: Background and Issues for Congress

    Science.gov (United States)

    2016-10-25

    Navy Virginia ( SSN -774) Class Attack Submarine Procurement: Background and Issues for Congress Ronald O’Rourke Specialist in Naval Affairs......Congressional Research Service Summary The Navy has been procuring Virginia ( SSN -774) class nuclear-powered attack submarines since FY1998. The two Virginia

  17. Patrones de distribución de la flora vascular acuática estricta en el estado de Tamaulipas, México Distributional patterns of the strictly aquatic vascular flora in the state of Tamaulipas, Mexico

    Directory of Open Access Journals (Sweden)

    Arturo Mora-Olivo

    2008-12-01

    Full Text Available Se analizaron los patrones de riqueza y distribución de las plantas vasculares acuáticas estrictas en el estado de Tamaulipas, México. Se registraron 93 especies, 62 de las cuales son típicas de ambientes lénticos. La subcuenca Río Tamesí fue la que registró el mayor número de especies (68, 73.1%. No se registraron especies endémicas del estado, aunque existen 2 especies restringidas al territorio mexicano (Lobelia purpusii y Oserya coulteriana. Se consideran como raras 29 especies (31.2% por presentarse en una sola subcuenca y sólo 2 especies están distribuidas ampliamente en la mayoría de éstas (Bacopa monnieri y Echinodorus berteroi. Un análisis de parsimonia de endemismos (PAE de las subcuencas hidrológicas del estado con base en la presencia compartida de especies reveló que las plantas acuáticas estrictas presentan un patrón de distribución anidado. Se concluye que las plantas vasculares acuáticas estrictas de Tamaulipas son parte de una misma unidad florística y que su distribución obedece a gradientes altitudinales, latitudinales y climáticos.Patterns of distribution and richness of strictly aquatic vascular plants of the state of Tamaulipas, Mexico, were analyzed. We registered 93 species of strictly aquatic vascular plants, which 62 are typical from lentic environments. The Río Tamesí sub-basin contains the highest number of species (68, 73.1%. There are no endemic species to the state of Tamaulipas, but we found 2 species endemic to Mexico (Lobelia purpusii and Oserya coulteriana. Twenty nine species (31.2% are considered rare, because they are present in a single sub-basin; only 2 species are widely distributed in most of them (Bacopa monnieri and Echinodorus berteroi. A parsimony analysis of endemicity (PAE of the hydrological sub-basins represented in this state based on the shared presence of species suggested that the strictly aquatic vascular plants have a nested distributional pattern. We conclude that

  18. Are strict vegetarians protected against prostate cancer?

    Science.gov (United States)

    Tantamango-Bartley, Yessenia; Knutsen, Synnove F; Knutsen, Raymond; Jacobsen, Bjarne K; Fan, Jing; Beeson, W Lawrence; Sabate, Joan; Hadley, David; Jaceldo-Siegl, Karen; Penniecook, Jason; Herring, Patti; Butler, Terry; Bennett, Hanni; Fraser, Gary

    2016-01-01

    According to the American Cancer Society, prostate cancer accounts for ∼27% of all incident cancer cases among men and is the second most common (noncutaneous) cancer among men. The relation between diet and prostate cancer is still unclear. Because people do not consume individual foods but rather foods in combination, the assessment of dietary patterns may offer valuable information when determining associations between diet and prostate cancer risk. This study aimed to examine the association between dietary patterns (nonvegetarian, lacto-ovo-vegetarian, pesco-vegetarian, vegan, and semi-vegetarian) and prostate cancer incidence among 26,346 male participants of the Adventist Health Study-2. In this prospective cohort study, cancer cases were identified by matching to cancer registries. Cox proportional hazards regression analysis was performed to estimate HRs by using age as the time variable. In total, 1079 incident prostate cancer cases were identified. Around 8% of the study population reported adherence to the vegan diet. Vegan diets showed a statistically significant protective association with prostate cancer risk (HR: 0.65; 95% CI: 0.49, 0.85). After stratifying by race, the statistically significant association with a vegan diet remained only for the whites (HR: 0.63; 95% CI: 0.46, 0.86), but the multivariate HR for black vegans showed a similar but nonsignificant point estimate (HR: 0.69; 95% CI: 0.41, 1.18). Vegan diets may confer a lower risk of prostate cancer. This lower estimated risk is seen in both white and black vegan subjects, although in the latter, the CI is wider and includes the null. © 2016 American Society for Nutrition.

  19. "Strict" Anadeixis, Discourse Deixis and Text Structuring

    Science.gov (United States)

    Cornish, Francis

    2011-01-01

    Taking English as the example language, the article begins by presenting a Scale of indexicality characterizing context-bound expression types, ranging from those signalling pure deixis at one pole, to ones expressing pure anaphora at the other. On the basis of this Scale, the article attempts to determine the specific way in which demonstratives…

  20. Unconditional bases and strictly convex dual renormings

    Czech Academy of Sciences Publication Activity Database

    Smith, Richard James; Troyanski, S.

    2009-01-01

    Roč. 41, č. 5 (2009), s. 831-840 ISSN 0024-6093 R&D Projects: GA AV ČR IAA100190801; GA ČR GA201/07/0394 Institutional research plan: CEZ:AV0Z10190503 Keywords : descroptive compact spaces * Banach spaces * norms Subject RIV: BA - General Mathematics Impact factor: 0.757, year: 2009 http://blms.oxfordjournals.org/content/41/5/831

  1. On Fixed Points of Strictly Causal Functions

    Science.gov (United States)

    2013-04-08

    languages such as VHDL (see [1]) and SystemC (see [2]), modeling and simulation tools such as Simulink and LabVIEW, network simulation tools such as ns-2/ns...interesting direction for future 49 work. References [1] IEEE standard VHDL language reference manual. IEEE Std 1076-2000, pages i–290, 2000. [2] IEEE

  2. Strictly convex functions on complete Finsler manifolds

    Indian Academy of Sciences (India)

    minimum set of a super Busemann function contains a soul of M. Clearly, a complete simply connected Riemannian manifold H of non-positive sec- tional curvature, called Hadamard manifold, has the property that the distance function to an arbitrary fixed point is strongly convex exhaustion. Also, the exponential map expp :.

  3. Strictly convex functions on complete Finsler manifolds

    Indian Academy of Sciences (India)

    convex functions on the metric structures of complete Finsler manifolds. More precisely we discuss ... map expp at some point p ∈ M (and hence at every point on M) is defined on the whole tangent space Mp to M at ... The influence of the existence of convex functions on the metric and topology of under- lying manifolds has ...

  4. Vocational technical and adult education: Status, trends and issues related to electronic delivery

    Science.gov (United States)

    Rothenberg, D.

    1973-01-01

    Data are analyzed, and trends and issues are discussed to provide information useful to the systems designer who wishes to identify and assess the opportunities for large scale electronic delivery in vocational/technical and adult education. Issues connected with vocational/technical education are investigated, with emphasis on those issues in the current spotlight which are relevant to the possibilities of electronic delivery. The current role of media is examined in vocational/technical instruction.

  5. The trends and issues about drive for thinness and eating behavior

    OpenAIRE

    Tazaki, Shinji

    2007-01-01

    The purpose of this study was to examine the recent trends and issues on the drive for thinness and eating behavior of adolescent females. In Japan, the number of eating disorders in adolescent female is rapidly increasing. And it is considered that the number of individuals who are not given a diagnosis of eating disorder but express a problematic eating behavior is on the increase. Through review researches, it was found that many psychological and sociocultural factors influenced the drive...

  6. Conventional Prompt Global Strike and Long-Range Ballistic Missiles: Background and Issues

    Science.gov (United States)

    2016-02-24

    Silver Bullet? Asking the Right Questions About Conventional Prompt Global Strike (Washington, DC: Carneige Endowment for International Peace, 2013), pp...124 James M. Acton, Silver Bullet? Asking the Right Questions About Prompt Global Strike (Washington, DC: Carnegie Endowment for International Peace, 2013), pp. 120-129. ...Conventional Prompt Global Strike and Long-Range Ballistic Missiles: Background and Issues Amy F. Woolf Specialist in Nuclear Weapons Policy

  7. Availability and Efficacy of Ballast Water Treatment Technology: Background and Issue Paper

    Science.gov (United States)

    2010-06-01

    Technology, Veolia Water Solutions & Technologies (CleanBallast) System and Greenship Sedinox® Ballast Water Management System. Note that the only...Cape Town - 4 2000+ MEPC 53/2/16 RWO GmbH Marine Water Technology, Veolia Water Solutions & Technologies (CleanBallast!) Filtration...Availability and Efficacy of Ballast Water Treatment Technology: Background and Issue Paper June 2010 Ryan Albert1, Rich

  8. Biological conversion of methane to chemicals and fuels: technical challenges and issues.

    Science.gov (United States)

    Hwang, In Yeub; Nguyen, Anh Duc; Nguyen, Thu Thi; Nguyen, Linh Thanh; Lee, Ok Kyung; Lee, Eun Yeol

    2018-04-01

    Methane is a promising next-generation carbon feedstock for industrial biotechnology due to its low price and huge availability. Biological conversion of methane to valuable products can mitigate methane-induced global warming as greenhouse gas. There have been challenges for the conversion of methane into various chemicals and fuels using engineered non-native hosts with synthetic methanotrophy or methanotrophs with the reconstruction of synthetic pathways for target products. Herein, we analyze the technical challenges and issues of potent methane bioconversion technology. Pros and cons of metabolic engineering of methanotrophs for methane bioconversion, and perspectives on the bioconversion of methane to chemicals and liquid fuels are discussed.

  9. Facts and issues of direct disposal of spent fuel; Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Parks, P.B.

    1993-10-01

    This report reviews those facts and issues that affect the direct disposal of spent reactor fuels. It is intended as a resource document for those impacted by the current Department of Energy (DOE) guidance that calls for the cessation of fuel reprocessing. It is not intended as a study of the specific impacts (schedules and costs) to the Savannah River Site (SRS) alone. Commercial fuels, other low enriched fuels, highly enriched defense-production, research, and naval reactor fuels are included in this survey, except as prevented by rules on classification.

  10. Supply Chain Management on IBS Implementation in Klang Valley Construction Industry: Challenges and Issues

    Science.gov (United States)

    Azrizal Fauzi, Mohd; Hasim, Sulaiman; Awang, Anizah; Ridzuan, Ahmad Ruslan Mohd; Nur Yunus, Juzailah

    2017-12-01

    Industrialized Building System (IBS) is a system where the components of the building are manufactured in a factory and it will be transported to the site to form the structures. The supply chain management (SCM) is a system where the delivery flows of the IBS products from manufacturers to the site. The aim of this research is to identify the major challenges and to analyze the issues on IBS implementation in SCM in Klang Valley from the manufacturers perspective. The methodology used in this paper is based on primary data through questionnaire and interview. Questionnaires were sent to the Manufacturers. It can be concluded that this paper attempts to present more on the challenges and issues that those companies of manufacturers faced during their success journey in finding integration in their supply chain. The main contributions of this paper are integrating all the supply chain integration challenges and issues on IBS. Therefore, these contributions will be helpful for the organization of manufacturers and IBS players that establish the integration in their SCM.

  11. Early Career Mentoring for Translational Researchers: Mentee Perspectives on Challenges and Issues

    Science.gov (United States)

    Keller, Thomas E.; Collier, Peter J.; Blakeslee, Jennifer E.; Logan, Kay; McCracken, Karen; Morris, Cynthia

    2014-01-01

    Background and purposes The education and training of early career biomedical translational researchers often involves formal mentoring by more experienced colleagues. This study investigated the nature of these mentoring relationships from the perspective of mentees. The objective was to understand the challenges and issues encountered by mentees in forming and maintaining productive mentoring relationships. Method Three focus groups (n=14) were conducted with early career researchers who had mentored career development awards. Thematic analysis identified, categorized, and illustrated the challenges and issues reported by mentees. Results The range of mentee challenges was reflected in five major categories: 1) network—finding appropriate mentors to meet various needs; 2) access—structuring schedules and opportunities to receive mentoring; 3) expectations—negotiating the mechanics of the mentoring relationship and its purpose; 4) alignment—managing mentor-mentee mismatches regarding interests, priorities, and goals; and 5) skills and supports—developing the institutional supports to be successful. Conclusions Mentoring relationships created for academic training and career development contend with tasks common to many other relationships, namely recognizing compatibility, finding time, establishing patterns, agreeing to goals, and achieving aims. Identifying challenges faced by mentees can facilitate the development of appropriate trainings and supports to foster mentoring relationships in academic and career settings. PMID:25010230

  12. Pedagogical Lexicography: Towards a New and Strict Typology Corresponding to the Present State-of-the-Art Pedagogiese leksikografie: Op weg na 'n nuwe en streng tipologie wat ooreenstem met die huidige gebruik daarvan.

    Directory of Open Access Journals (Sweden)

    Sven Tarp

    2012-01-01

    Full Text Available

    A frequent and well-known problem within lexicography is the use of various terms to denominate the same phenomenon as well as the use of the same term to denominate various, completely different phenomena. Such a non-systematic terminology may lead to confusion in the discipline and hamper its theoretical and practical development. The problem is especially severe within so-called pedagogical lexicography. A short panoramic review shows that especially the terms "pedagogical lexicography/dictionaries", "didactic lexicography/dictionaries", "school dictionaries" and "learners' dictionaries" are used with a lot of different meanings that vary from author to author, from country to country, from culture to culture. Although publishing houses could hardly be expected to use a strict terminology for their products, this should nevertheless be expected from theoretical lexicography. In order to overcome the present confusion, it is therefore urgent to establish a typology that can be used as reference by scholars dealing theoretically with the subfield of pedagogical lexicography. The article will first show the amazing variety of meanings addressed to the various terms in the theoretical literature. It will then approach the problem along two different lines: 1 establishing a clear definition of the terms "pedagogical", "didactic", "school" and "learner" in a lexicographical perspective, and 2 referring to the existing practice where the terms are frequently used in a much broader sense than in the theoretical literature. Based upon these considerations, a new and strict typology that corresponds to the present practice of pedagogical lexicography will be presented.

    Keywords: pedagogical lexicography; pedagogical dictionaries; learners' lexicography; learners' dictionaries; school dictionaries; children's dictionaries; desk dictionaries; college dictionaries; dictionaries for foreign-language learners; dictionaries

  13. An Effective Method to Detect Volatile Intermediates Generated in the Bioconversion of Coal to Methane by Gas Chromatography-Mass Spectrometry after In-Situ Extraction Using Headspace Solid-Phase Micro-Extraction under Strict Anaerobic Conditions.

    Science.gov (United States)

    Liu, Jianmin; Wang, Baoyu; Tai, Chao; Wu, Li; Zhao, Han; Guan, Jiadong; Chen, Linyong

    2016-01-01

    Bioconversion of coal to methane has gained increased attention in recent decades because of its economic and environmental advantages. However, the mechanism of this process is difficult to study in depth, partly because of difficulties associated with the analysis of intermediates generated in coal bioconversion. In this investigation, we report on an effective method to analyze volatile intermediates generated in the bioconversion of coal under strict anaerobic conditions. We conduct in-situ extraction of intermediates using headspace solid-phase micro-extraction followed by detection by gas chromatography-mass spectrometry. Bioconversion simulation equipment was modified and combined with a solid-phase micro-extraction device. In-situ extraction could be achieved by using the combined units, to avoid a breakdown in anaerobic conditions and to maintain the experiment continuity. More than 30 intermediates were identified qualitatively in the conversion process, and the variation in trends of some typical intermediates has been discussed. Volatile organic acids (C2-C7) were chosen for a quantitative study of the intermediates because of their importance during coal bioconversion to methane. Fiber coating, extraction time, and solution acidity were optimized in the solid-phase micro-extraction procedure. The pressure was enhanced during the bioconversion process to investigate the influence of headspace pressure on analyte extraction. The detection limits of the method ranged from 0.0006 to 0.02 mmol/L for the volatile organic acids and the relative standard deviations were between 4.6% and 11.5%. The volatile organic acids (C2-C7) generated in the bioconversion process were 0.01-1.15 mmol/L with a recovery range from 80% to 105%. The developed method is useful for further in-depth research on the bioconversion of coal to methane.

  14. Agathobaculum butyriciproducens gen. nov.  sp. nov., a strict anaerobic, butyrate-producing gut bacterium isolated from human faeces and reclassification of Eubacterium desmolans as Agathobaculum desmolans comb. nov.

    Science.gov (United States)

    Ahn, Sharon; Jin, Tae-Eun; Chang, Dong-Ho; Rhee, Moon-Soo; Kim, Hyun Ju; Lee, Sang Jun; Park, Doo-Sang; Kim, Byoung-Chan

    2016-09-01

    A novel bacterial strain, SR79T, was isolated from a Korean faecal sample and characterized using a polyphasic approach. SR79T was found to be a strictly anaerobic, Gram-stain-positive, non-spore-forming, non-motile, catalase- and oxidase-negative short rod with no flagella. SR79T grew optimally at 37 °C in the presence of 0.5 % (w/v) NaCl at pH 7. The NaCl range for growth was 0-1 % (w/v). The isolate produced butyric acid (>18  mM) as a major end product. A phylogenetic analysis based on 16S rRNA gene sequences revealed that the most closely related type strains were Eubacteriumdesmolans ATCC 43058T and Butyricicoccus pullicaecorum 25-3T (96.4 and 96.0 % similarity, respectively). The DNA G+C content was determined to be 52.9 mol%. The major cellular fatty acids (>10 %) were C16 : 0, C18 : 1cis-9, C19 : 1 cyc 9,10 and C14 : 0. Meso-diaminopimelic acid was present in the cell wall peptidoglycan and the cell wall hydrolysates contained ribose, glucose and galactose. The 16S rRNA gene sequence similarity, phylogenetic analysis, chemotaxonomic and phenotypic characteristics allowed differentiation of SR79T, which represents a novel species of a new genus within the family Ruminococcaceae, for which the name Agathobaculum butyriciproducens gen. nov. sp. nov. is proposed. The type strain is SR79T (=KCTC 15532T=DSM 100391T). Based on the results of this study, it is also proposed to transfer Eubacteriumdesmolans to this new genus, as Agathobaculum desmolans comb. nov. The type strain of Agathobaculum desmolans is ATCC 43058T (=CCUG 27818T).

  15. Book Review: Lobbying the European Union: Institutions, Actors and Issues, David Coen and Jeremy Richardson (eds.

    Directory of Open Access Journals (Sweden)

    Alexandra Pop

    2013-03-01

    Full Text Available The volume "Lobbying the European Union: Institutions, Actors and Issues", collects 16 articles on interest group politics at EU level, focusing on the main elements of European lobbying - the existing relations between the EU institutions and the special interests, the main differences between NGO and business lobbying, the specific lobbying strategies adopted in EU's main policy sectors or lobbying regulations. The volume captures the main changes that took place on the European lobbying scene in the last two decades, period in which most EU institutions developed new points of access for lobbyists, while the interest groups became more specialized. The success of an EU lobbying campaign seems to be determined by a combination of various factors such as: a good knowledge of the EU environment, a wise usage of both financial resources and expertise, direct lobbying complemented by an efficient usage of domestic routes and the capability of creating smart alliances.

  16. A BRIEF ANALYSIS OF THE TOURISM SECTOR - CURRENT TRENDS AND ISSUES IN THE BULGARIAN TOURIST BUSINESS

    Directory of Open Access Journals (Sweden)

    Kostadin Valkov

    2016-03-01

    Full Text Available Thе analysis presented in current article deepens and summarizes the results of an economic study focused on the management of human resources in the sector "Tourism". The expected changes in organizational and technological terms are taken into account. The law on tourism in the Republic of Bulgaria and the types of taxes that directly and indirectly affect those employed in tourism are considered. Leading accents are the current trends and issues that arise from the lack of skilled workers in this sector and their deficit caused by the seasonal nature of employment. Growing gray economy is concerned as a major obstacle to development of the tourism industry and its future.

  17. Cloud Based Educational Systems 
And Its Challenges And Opportunities And Issues

    Directory of Open Access Journals (Sweden)

    Prantosh Kr. PAUL

    2014-01-01

    Full Text Available Cloud Computing (CC is actually is a set of hardware, software, networks, storage, services an interface combines to deliver aspects of computing as a service. Cloud Computing (CC actually uses the central remote servers to maintain data and applications. Practically Cloud Computing (CC is extension of Grid computing with independency and smarter tools and technological gradients. Healthy Cloud Computing helps in sharing of software, hardware, application and other packages with the help of internet tools and wireless media. Cloud Computing, has benefits in several field and applications domain such as Agriculture, Business and Commerce, Health Care, Hospitality and Tourism, Education and Training sector and so on. In Education Systems, it may be applicable in general regular education and other education systems including general and vocational training. This paper is talks about opportunities that provide Cloud Computing (CC; however the intention would be challenges and issues in relation to Education, Education Systems and Training programme.

  18. 8 CFR 286.9 - Fee for processing applications and issuing documentation at land border Ports-of-Entry.

    Science.gov (United States)

    2010-01-01

    ... SECURITY IMMIGRATION REGULATIONS IMMIGRATION USER FEE § 286.9 Fee for processing applications and issuing... Card, issued by the DOS, or a passport and combined B-1/B-2 visa and non-biometric BCC (or similar...

  19. A Categorical Content Analysis of Highly Cited Literature Related to Trends and Issues in Special Education.

    Science.gov (United States)

    Arden, Sarah V; Pentimonti, Jill M; Cooray, Rochana; Jackson, Stephanie

    2017-07-01

    This investigation employs categorical content analysis processes as a mechanism to examine trends and issues in a sampling of highly cited (100+) literature in special education journals. The authors had two goals: (a) broadly identifying trends across publication type, content area, and methodology and (b) specifically identifying articles with disaggregated outcomes for students with learning disabilities (LD). Content analyses were conducted across highly cited (100+) articles published during a 20-year period (1992-2013) in a sample ( n = 3) of journals focused primarily on LD, and in one broad, cross-categorical journal recognized for its impact in the field. Results indicated trends in the article type (i.e., commentary and position papers), content (i.e., reading and behavior), and methodology (i.e., small proportions of experimental and quasi-experimental designs). Results also revealed stability in the proportion of intervention research studies when compared to previous analyses and a decline in the proportion of those that disaggregated data specifically for students with LD.

  20. Implementing standard setting into the Conjoint MAFP/FRACGP Part 1 examination - Process and issues.

    Science.gov (United States)

    Chan, S C; Mohd Amin, S; Lee, T W

    2016-01-01

    The College of General Practitioners of Malaysia and the Royal Australian College of General Practitioners held the first Conjoint Member of the College of General Practitioners (MCGP)/Fellow of Royal Australian College of General Practitioners (FRACGP) examination in 1982, later renamed the Conjoint MAFP/FRACGP examinations. The examination assesses competency for safe independent general practice and as family medicine specialists in Malaysia. Therefore, a defensible standard set pass mark is imperative to separate the competent from the incompetent. This paper discusses the process and issues encountered in implementing standard setting to the Conjoint Part 1 examination. Critical to success in standard setting were judges' understanding of the process of the modified Angoff method, defining the borderline candidate's characteristics and the composition of judges. These were overcome by repeated hands-on training, provision of detailed guidelines and careful selection of judges. In December 2013, 16 judges successfully standard set the Part 1 Conjoint examinations, with high inter-rater reliability: Cronbach's alpha coefficient 0.926 (Applied Knowledge Test), 0.921 (Key Feature Problems).

  1. An Update on Travel Vaccines and Issues in Travel and International Medicine.

    Science.gov (United States)

    Rogers, Bonnie; Bunn, William B; Connor, Bradley A

    2016-08-23

    The fields of travel and international medicine are rapidly changing and growing. The role of occupational and travel health nurses is expanding and should be a focus for the future. At the American Association of Occupational Health Nurses Annual meeting on March 24, 2015, in Boston, five presentations were included in the session, An Update on Travel Vaccines and Issues in Travel and International Medicine. This article summarizes three of the presentations and includes a portion of the information generated by the Centers for Disease Control and Prevention (CDC) included in the fourth presentation. The first section focuses on the Essential Elements of Travel Medicine Programs including the pre-travel care assessment, trip research and risk identification, medication intervention review, non-pharmaceutical and prevention strategies, and post-travel care. The next section is an overview of key issues for business travelers. The growth in the number of international business travelers and unique aspects of business travel are emphasized in a comprehensive travel health program. This section also includes a discussion of expatriates and their special risks identified in recent literature (e.g., an assessment of the significant costs of health events and productivity losses by both business travelers and expatriates). The final section offers a specific example of a vaccine-preventable disease, namely, Japanese encephalitis (JE) virus, and needed changes in JE vaccine recommendations. © 2016 The Author(s).

  2. Challenges and issues facing the future of nursing education: implications for ethnic minority faculty and students.

    Science.gov (United States)

    Davis, Sheila P; Davis, Danyetta D

    2010-01-01

    Current trends in higher education in the United States demand that nursing take stock of how it is prepared or being prepared to face challenges and issues impacting on its future. The intense effort made to attract students to pursue advanced training in science and engineering in the United States pales in comparison to the numbers of science and engineering majors produced yearly in international schools. As a result, more and more jobs are being outsourced to international markets. Could international outsourcing become a method of nursing education? Authors submit that to remain competitive, the nursing profession must attract a younger cohort of technologically savvy students and faculty reflective of the growing diverse population in the United States. Additionally, nursing programs in research universities face even more daunting challenges as it relates to mandates for funded research programs of educational units. This article offers suggestions and recommendations for nursing programs in higher education institutions on ways to attract and retain ethnic minorities and of how to harness the power of research to address burgeoning societal health challenges.

  3. Post-construction monitoring for birds and bats : an examination of methods and issues

    International Nuclear Information System (INIS)

    Ebner, D.; Korpijaakko, C.

    2009-01-01

    The Canadian Environmental Assessment Act (CEAA) stipulates that bird and bat monitoring studies should be conducted following the construction of most wind turbine projects in Canada. The objectives of the monitoring studies are to verify the accuracy of the environmental assessment; determine the effectiveness of any measures taken to mitigate the adverse environmental effects of a project; and to evaluate the cumulative effects on species diversity and numbers. This presentation discussed post-construction monitoring for birds and bats and provided an examination of methods and issues. It emphasized why post-construction monitoring is important. Environmental effects that were examined in the presentation were changes in breeding birds; changes in passage migrants or wintering birds; changes in bat activity; and mortality monitoring/carcass surveys. The key issues regarding the design and implementation of post-construction monitoring programs include variation in field and analytical methods; protocols implemented that can add uncertainty and bias to estimates of mortality; and comparisons of project-specific results with other projects. Other topics that were addressed included federal requirements; provincial requirements; post-construction surveys and carcass searches; search efficiency and analysis. The presentation concluded with a discussion regarding the need for standardization. figs.

  4. Two-wheeled motor vehicle technology in India: Evolution, prospects and issues

    International Nuclear Information System (INIS)

    Iyer, Narayan V.; Badami, Madhav G.

    2007-01-01

    By providing affordable mobility to millions of people, two-wheeled motor (M2W) vehicles play a vital role in urban transport in India and other low-income Asian countries. At the same time, these vehicles contribute significantly to urban transport impacts and energy consumption, and are characterized by high emissions and traffic mortalities per passenger-kilometre. Given the importance of technology in the popularity of these vehicles and their transport impacts, this paper discusses the evolution of M2W vehicle technology in India, and contributory factors including market forces, environmental regulation, and industry R and D efforts. It then discusses technologies that we expect to be implemented for M2W vehicles in India over the next two or three decades, the likely implications of these technologies in terms of vehicle price, emissions, fuel economy and service life, and issues related to vehicle technology development and implementation. The paper shows that while the Indian M2W vehicle industry has achieved a transformation in innovation, product development and quality in response to market demands and environmental concerns, various technological and institutional challenges need to be addressed by this and the oil and vehicle servicing industries, and government agencies at all levels, to successfully deploy advanced vehicle technologies

  5. Partner Country Series: Understanding Energy Challenges in India - Policies, Players and Issues

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    A combination of rapidly increasing energy demand and fuel imports plus growing concern about economic and environmental consequences is generating growing calls for effective and thorough energy governance in India. Numerous policy reforms over the past 20 years have shifted the country’s energy sector from a state-dominated system towards one that is based on market principles. However, with the reform process left unfinished, India now finds itself trapped halfway along the transition to an open and well-performing energy sector. India suffered from the largest power outage ever in late July 2012, affecting nearly half of the population. While this incident highlights the importance of modern and smart energy systems, it indicates that the country is increasingly unable to deliver a secure supply of energy to its population, a quarter of which still lacks access to electricity. Understanding Energy Challenges in India aims to provide an informative and holistic understanding of India’s energy sector to stakeholders in India as well as the broad public. The publication explores in detail the policies, players and issues of the country’s power, coal, oil and gas, renewables and nuclear sectors. It also highlights the key challenges India faces, challenges that must be resolved for the evolution of the fast-growing country’s energy sector towards a sustainable energy future and eventually critical for the prospects of the Indian and global economies.

  6. Methods and Issues for the Combined Use of Integral Experiments and Covariance Data

    International Nuclear Information System (INIS)

    Salvatores, M.; Palmiotti, G.; Aliberti, G.; McKnight, R.; Archier, P.; De Saint Jean, C.; Dupont, E.; Herman, M.; Ishikawa, M.; Sugino, K.; Ivanova, T.; Ivanov, E.; Kim, S.J.; Kodeli, I.; Trkov, A.; Manturov, G.; Pelloni, S.; Perfetti, C.; Rearden, B.T.; Plompen, A.; Rochman, D.; Wang, W.; Wu, H.; Yang, W.S.

    2013-01-01

    The Working Party on International Nuclear Data Evaluation Co-operation (WPEC) has been established under the aegis of the OECD/NEA Nuclear Science Committee (NSC) to promote the exchange of information on nuclear data evaluations, validation and related topics. Its aim is also to provide a framework for co-operative activities between the members of the major nuclear data evaluation projects. This includes the possible exchange of scientists in order to encourage co-operation. Requirements for experimental data resulting from this activity are compiled. The WPEC determines common criteria for evaluated nuclear data files with a view to assessing and improving the quality and completeness of evaluated data. The parties to the project are: BROND (Russian Federation), ENDF (United States), JENDL (Japan) and JEFF (other NEA Data Bank member countries). Co-operation with evaluation projects of non-NEA countries, specifically the Chinese CENDL project, is organised through the Nuclear Data Section of the International Atomic Energy Agency (IAEA). This report has been issued by the WPEC Subgroup 33, whose mission was to review methods and issues of the combined use of integral experiments and covariance data, with the objective of recommending a set of best and consistent practices in order to improve evaluated nuclear data files. In particular, it is shown that the statistical adjustment methodologies used worldwide are well understood and essentially equivalent. The results of the benchmark adjustment exercise indicate common trends for important data, even when they start from different basic nuclear data and different covariance matrices. In this respect, adjustment methodologies can provide a powerful tool to improve nuclear data (and associated uncertainties) if used in an appropriate manner

  7. Reversibility of Decisions and Retrievability of Radioactive Waste: An Overview of Regulatory Positions and Issues

    International Nuclear Information System (INIS)

    Ruiz-Lopez, Carmen; Pescatore, Claudio

    2015-02-01

    The Radioactive Waste Management Committee (RWMC) of the NEA has been at the forefront worldwide in examining the topic of Reversibility and Retrievability (R and R). As early as 2001, an NEA survey-based report entitled 'Reversibility and Retrievability in Geological Disposal of Radioactive Waste' provided an overview of R and R by an ad-hoc group of experts from 11 NEA Member countries. The 2001 report (NEA 2001) observed that national safety regulations dealt mainly with operational safety and design targets for long-term (post-closure) safety and relatively little consideration was given to retrievability/reversibility or its implications. Yet, policy frames saw benefits from retrievability. In 2007, the RWMC launched the NEA R and R project with participation from 15 countries and two international organisations. The project included, amongst its members, representatives of six organisations involved in regulation, five regulatory authorities of five countries and one technical support organisation to the safety authorities. The project aimed to improve awareness amongst the RWMC constituency of the breadth of issues and positions regarding the concepts of R and R with the goal of providing a neutral overview of relevant issues and viewpoints in OECD countries. Hence substantial attention was given to R and R regulatory issues mainly in the context of decision making for repository development. The report (NEA 2011) points out regulatory issues, including safety criteria and licensing considerations. The present document presents an overview of findings, positions, boundary conditions and issues based on the results of the R and R project of 2007-2011 (stepwise decision making and reversibility, regulatory authorisations and R and R, decision making for retrieval) and of the Reims conference of December 2010 (terminology and definitions, legal and policy context, motivations for R and R, practical aspects, stakeholders confidence aspects)

  8. Expert systems development: some problems, motives and issues in an exploratory study

    International Nuclear Information System (INIS)

    Mehdi Sagheb-Tehrani.

    1993-10-01

    Even though expert systems (ES) have been in use since the early eighties, there is a remarkable lack of a strong theoretical base for handling expert systems development problems. There is a requirement in the ES field for theories or explanatory models to formulate propositions, to conduct research and interpret findings in a coherent way. This work presents an exploratory investigation designed to identify some problems, motives and issues associated with developing expert systems. Totally, twenty-five expert systems were developed by various organizations which participated in the study. The study attempts to provide evidence that either supports or refutes the anecdotes, gossips and speculations currently being spread through the academic journals dealing with the expert systems development in organizations. This study provides evidence that knowledge acquisition is indeed the bottleneck of expert systems development. It also points out that most expert systems are still in the prototype stage, and that current expert systems are mostly used for aiding the decision making of less skilled domain personnel and to a lesser extent for advice to experts. The rationale behind these uses seems to be the search by organizations for better decision making in the hope of improving competitiveness. A conceptual model of expert systems development is introduced based upon theoretical studies and the findings of this study from which some hypotheses are drawn. The main objective of the model is to contribute to a larger theoretical framework. Another aim is to create a broader theoretical framework for expert systems development in order to implement such systems more successfully. The results of the study confirm that the linkages of various concepts involved in the expert systems development process are very important for the design of a successful expert system project

  9. 78 FR 59228 - Sale and Issue of Marketable Book-Entry Treasury Bills, Notes, and Bonds; Corrections

    Science.gov (United States)

    2013-09-26

    ... and Issue of Marketable Book-Entry Treasury Bills, Notes, and Bonds; Corrections AGENCY: Fiscal... accommodate the public offering of floating rate notes. This document corrects the final regulations by.... Accordingly, 31 CFR part 356 is corrected by making the following correcting amendments: PART 356--SALE AND...

  10. Dealing with symptoms and issues of hospitalized patients with cancer in indonesia: the role of families, nurses, and physicians

    NARCIS (Netherlands)

    Effendy, C.; Vissers, K.; Tejawinata, S.; Vernooij-Dassen, M.; Engels, Y.M.

    2015-01-01

    OBJECTIVE: Patients with cancer often face physical, psychological, social, spiritual, and emotional symptoms. Our aim was to study symptoms and issues of hospitalized patients with cancer in Indonesia, a country with strong family ties, and how family members, nurses, and physicians deal with them.

  11. Authoritative parenting and issue involvement as indicators of ad recall: an empirical investigation of anti-drug ads for parents.

    Science.gov (United States)

    Quick, Brian L; Stephenson, Michael T

    2007-01-01

    This investigation explores the role of authoritative parenting and issue involvement in regard to the recall of parental anti-drug ads encouraging child monitoring. In addition, the study tested whether issue involvement mediates the association between authoritative parenting and recall of parental anti-drug television ads among parents (N = 185) with adolescents in Grades 6, 7, and 8. The results indicate that (a) authoritative parenting is positively associated with favorable attitudes toward monitoring children and issue involvement regarding adolescent drug use, (b) issue involvement is associated with ad recall, (c) issue involvement mediates the relationship between authoritative parenting and ad recall, (d) ad recall is not associated with favorable attitudes toward parental monitoring, and (e) favorable attitudes regarding parental monitoring are positively associated with intentions to engage in monitoring within the next 6 months.

  12. RENDS AND ISSUES IN DISTANCE EDUCATION: International Perspectives, Second Edition Edited by Lya Visser, Yusra Visser, Ray Amirault & Michael Simonson

    Directory of Open Access Journals (Sweden)

    Reviewed by Dilek ALTUNAY

    2013-07-01

    Full Text Available Over the last decade, the field of distance education (and e-learning has substantially strengthened and assumed a more international scope. There has been an impressive growth in the conceptual, empirical and experiential foundations of the field. Trends and Issues in Distance Education: International Perspectives (2nd Ed captures a representative snapshot of the breadth of current global trends and issues in distance education theory, research, and practice. Through 21 chapters (from over 30 international authors, the book documents new developments in distance education scholarship and practice, presenting a diverse set of viewpoints on the trends and issues affecting this increasingly central discipline. The book is for researchers, practitioners, and students. Chapters speak to the many creative ways in which distance education addresses learning and human development needs around the world. They focus on distance education in dissimilar settings that extend beyond the limitations of the dominating paradigms of the highly developed economies. Contributing authors touch upon conceptual as well as practical issues. They critically reflect on both large- and small-scale distance education initiatives, discussing the use of everything from the most advanced technologies (e.g., 3-D computing to the most rudimentary technologies (e.g., wind-up radios (Quated Amazon Pages This book makes a contribution to the field of distance education by offering a comprehensive overview and analysis of the current trends and issues in distance education. In addition, the book is well-organized and coherent in terms of presentation. The reader is guided by section editors who provides introduction to the sectio

  13. Dealing with symptoms and issues of hospitalized patients with cancer in indonesia: the role of families, nurses, and physicians.

    Science.gov (United States)

    Effendy, Christantie; Vissers, Kris; Tejawinata, Sunaryadi; Vernooij-Dassen, Myrra; Engels, Yvonne

    2015-06-01

    Patients with cancer often face physical, psychological, social, spiritual, and emotional symptoms. Our aim was to study symptoms and issues of hospitalized patients with cancer in Indonesia, a country with strong family ties, and how family members, nurses, and physicians deal with them. In 2011, 150 hospitalized cancer patients in 3 general hospitals in Indonesia were invited to fill in a questionnaire, which was based on the validated Problems and Needs of Palliative Care (short version) questionnaire. Descriptive statistics were performed. Of 119 patients (79%) who completed the questionnaire, 85% stated that their symptoms and issues were addressed. According to these patients, financial (56%), autonomy (36%), and psychosocial (34%) issues were most often addressed by the family alone. Physical symptoms (52%) and spiritual issues (33%) were addressed mainly by a combination of family, nurses, and physicians. Hospitalized patients with cancer in Indonesia felt that most of their symptoms and issues had been addressed, and the family was highly involved. The strong family ties in Indonesian culture may have contributed to this family role. More research is needed to clarify how this influences patient outcome, quality of care, and quality of life of both the patients and their families, along with the degree of partnership between families and professionals. This information might help answer the question what advantages and disadvantages the family role in caring for a hospitalized patient with cancer generates for the patient, the family, and professional caregivers. © 2014 World Institute of Pain.

  14. Two-sided messages for health risk prevention: the role of argument type, refutation, and issue ambivalence.

    Science.gov (United States)

    Cornelis, Erlinde; Cauberghe, Veroline; De Pelsmacker, Patrick

    2013-06-01

    Two experiments were conducted among adolescents in 2011 in urban parts of Belgium, Europe. The effectiveness of two-sided binge drinking and marijuana prevention messages was investigated in relation to argument type, refutation, and issue ambivalence. Study 1 (n = 373) serves as a baseline study for study 2 (n = 156). Data were collected through a printed questionnaire in classrooms in Flemish secondary schools. Analysis of variance (ANOVA) was used to analyze the data. Implications for health practitioners, as well as limitations and suggestions for further research are given.

  15. Touch-input compatible portable terminal for receiving and issuing orders; Touch nyuryoku kanona keitai hacchu tanmatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    A portable terminal with an 800-times-600-dot color display has been developed, useful in receiving and issuing orders in the distribution industry or the like. The terminal runs on Microsoft Windows(reg sign) CE 2.11 embedded as the operating system (OS), and exhibits a high affinity with the system. It uses Toshiba's CPU TX3922 and dedicated ASIC (Application Specific Integrated Circuit), and achieves an energy efficient uninterrupted 7-hour operation without degrading augmentability involving various peripheral interfaces such as the PC card, infrared communication, USB (Universal Serial Bus), PS/2 (Personal System/2), and the like. Since the terminal is to be touch-operated, the operator can issue orders while checking the inventories and utilize presentation on the display at negotiations on business. (translated by NEDO)

  16. Current status and issues of nuclear human resource development/General activities of Japan nuclear human resource development network

    International Nuclear Information System (INIS)

    Murakami, Hiroyuki; Hino, Sadami; Tsuru, Hisanori

    2013-01-01

    The Japan Nuclear Human Resource Development Network (JN-HRD Net) was established in November 2010 with the aim of developing a framework for mutual cooperation and information sharing among nuclear-related organizations. Although the tasks and goals of developing human resources in the nuclear field have been shifted since the accident at the Tokyo Electric Power Company (TEPCO) Fukushima Daiichi Nuclear Power Plant, the necessity of fostering capable personnel in this field stays unchanged and the importance of our network activities has further emphasized. The meeting of JN-HRD Net was held on the 5th of February 2013, where its activities by each field were reported and views and opinions were actively exchanged between more than 90 participants. This paper briefly describes current status and issues of JN-HRD Net and its general activities conducted by the JN-HRD Net secretariat. (J.P.N.)

  17. Designing health care environments: Part I. Basic concepts, principles, and issues related to evidence-based design.

    Science.gov (United States)

    Cesario, Sandra K

    2009-06-01

    A 2001 Institute of Medicine report captured the nation's attention regarding the dangers that can result from the health care environment. This report, fueled by the need for new facilities to be constructed, led to an explosion of research that now links the physical structure and design of health care facilities to the health and well-being of patients, nurses, other health care workers, and visitors. Continuing nursing education that highlights the importance of evidence-based design has been associated with measurable improvement in health care facilities' clinical outcomes, economic performance, employee productivity, customer satisfaction, and cultural congruency. Three major categories of outcomes can be impacted by evidence-based design: stress reduction, safety, and overall health care quality and ecology. In this article, Part I of a two-part series, the basic concepts, principles, and issues related to evidence-based design are introduced. Part II will describe continuing education programs available for nurses.

  18. Towards generalized synchronization of strictly different chaotic systems

    International Nuclear Information System (INIS)

    Femat, R.; Kocarev, L.; Gerven, L. van; Monsivais-Perez, M.E.

    2005-01-01

    This contribution addresses the problem of the generalized synchronization (GS) in different chaotic systems, and departs from chaotic systems in a triangular from, which can be derived from Lie derivatives. A state-feedback (full knowledge of both master and slave systems) scheme is designed, which achieves GS. The work includes illustrative examples; moreover an experimental setup is used to corroborate the obtained results

  19. Pedagogical Lexicography: Towards a New and Strict Typology ...

    African Journals Online (AJOL)

    Hausmann, Franz Josef. 1990. Das Kinderwörterbuch. Hausmann, Franz Josef, Oskar Reichmann,. Herbert Ernst Wiegand and Ladislav Zgusta (Eds.). Wörterbücher, Dictionaries, Dictionnaires. An International Encyclopedia of Lexicography II: 1365-1368. Berlin/New York: Walter de Gruy- ter. Hernández, Humberto. 1989.

  20. Assessing birth asphyxia using strictly observational signs, the ARC ...

    African Journals Online (AJOL)

    developed by Dr Sultan Omar Sultan was pre-tested at St Francis Hospital Ifakara in 2008 , then tested on 340 newborns in Temeke Hospital and Mnazi Mmoja Hospital. It was found be more sensitive, more specific and more reliable and ultimately ...

  1. A Balanced and Representative Corpus: The Effects of Strict Corpus ...

    African Journals Online (AJOL)

    Theoretically the Northern Sotho language is made up of almost 30 dialects while practically it is not so, because the standard language was formed from very few of its dialects. As a result, even today the language has no corpus which is balanced or representative owing to the fact that almost all of the available corpora ...

  2. Strictly modular probabilistic neural networks for pattern recognition

    Czech Academy of Sciences Publication Activity Database

    Grim, Jiří; Just, P.; Pudil, Pavel

    2003-01-01

    Roč. 13, č. 6 (2003), s. 599-615 ISSN 1210-0552 R&D Projects: GA ČR GA402/01/0981 Institutional research plan: CEZ:AV0Z1075907 Keywords : neural networks * distribution mixtures * pattern recognition Subject RIV: BB - Applied Statistics, Operational Research

  3. Evaluation of a strict protocol approach in managing women with ...

    African Journals Online (AJOL)

    3. Respiratory system. Respiratory rate, lung sounds and oxygen saturation. If the respiratory rate was increased, the oxygen saturation decreased or lung sounds were abnormal, arterial blood gas measurement and a chest X-ray was performed. 4. The hepatic system was evaluated by examining for jaundice and signs of ...

  4. Mixed Causal-Noncausal Autoregressions with Strictly Exogenous Regressors

    NARCIS (Netherlands)

    Hecq, Alain; Issler, J.V.; Telg, Sean

    2017-01-01

    The mixed autoregressive causal-noncausal model (MAR) has been proposed to estimate economic relationships involving explosive roots in their autoregressive part, as they have stationary forward solutions. In previous work, possible exogenous variables in economic relationships are substituted into

  5. 15 TOWARDS THE STRICT LEGAL ENFORCEMENT OF BEST ...

    African Journals Online (AJOL)

    Fr. Ikenga

    production has the potential to cause severe environmental degradation, not only to the physical environment, but also to ... approaches to achieving high environmental performance in the oil and gas sector and made some ..... bribes; the number of forums organised to discuss employee conditions; and the level of local.

  6. Modular PNML revisited: Some ideas for strict typing

    DEFF Research Database (Denmark)

    Kindler, Ekkart

    2007-01-01

    The Petri Net Markup Language (PNML) is currently standardised by ISO/IEC JTC1/SC7 WG 19 as Part 2 of ISO/IEC 15909. But, there is not yet a mechanism for structuring large Petri nets and for constructing Petri nets from modules. To this end, modular PNML has been proposed some time ago. But......, modular PNML has some problems. These problems along with ideas for their solution will be discussed in this paper. As a first step toward standardising a module concept for PNML in Part 3 of ISO/IEC 15909, this paper proposes a refined concept of modular PNML, which is independent of a particular kind...

  7. Are strict vegetarians protected against prostate cancer?1

    Science.gov (United States)

    Knutsen, Synnove F; Knutsen, Raymond; Jacobsen, Bjarne K; Fan, Jing; Beeson, W Lawrence; Sabate, Joan; Hadley, David; Jaceldo-Siegl, Karen; Penniecook, Jason; Herring, Patti; Butler, Terry; Bennett, Hanni; Fraser, Gary

    2016-01-01

    Background: According to the American Cancer Society, prostate cancer accounts for ∼27% of all incident cancer cases among men and is the second most common (noncutaneous) cancer among men. The relation between diet and prostate cancer is still unclear. Because people do not consume individual foods but rather foods in combination, the assessment of dietary patterns may offer valuable information when determining associations between diet and prostate cancer risk. Objective: This study aimed to examine the association between dietary patterns (nonvegetarian, lacto-ovo-vegetarian, pesco-vegetarian, vegan, and semi-vegetarian) and prostate cancer incidence among 26,346 male participants of the Adventist Health Study-2. Design: In this prospective cohort study, cancer cases were identified by matching to cancer registries. Cox proportional hazards regression analysis was performed to estimate HRs by using age as the time variable. Results: In total, 1079 incident prostate cancer cases were identified. Around 8% of the study population reported adherence to the vegan diet. Vegan diets showed a statistically significant protective association with prostate cancer risk (HR: 0.65; 95% CI: 0.49, 0.85). After stratifying by race, the statistically significant association with a vegan diet remained only for the whites (HR: 0.63; 95% CI: 0.46, 0.86), but the multivariate HR for black vegans showed a similar but nonsignificant point estimate (HR: 0.69; 95% CI: 0.41, 1.18). Conclusion: Vegan diets may confer a lower risk of prostate cancer. This lower estimated risk is seen in both white and black vegan subjects, although in the latter, the CI is wider and includes the null. PMID:26561618

  8. The Fixed-Point Theory of Strictly Causal Functions

    Science.gov (United States)

    2013-06-09

    description languages such as VHDL (see [1]) and SystemC (see [2]), modeling and simulation tools such as Simulink and LabVIEW, network simulation tools such...context is another interesting direction for future work. References [1] IEEE standard VHDL language reference manual. IEEE Std 1076-2000, pages i–290, 2000

  9. Strict topoligies in non-Archimedean function spaces

    Directory of Open Access Journals (Sweden)

    A. K. Katsaras

    1984-01-01

    Full Text Available Let F be a non-trivial complete non-Archimedean valued field. Some locally F-convex topologies, on the space Cb(X,E of all bounded continuous functions from a zero-dimensional topological space X to a non-Archimedean locally F-convex space E, are studied. The corresponding dual spaces are also investigated.

  10. Indonesian parliament adopts strict anti-drug law.

    Science.gov (United States)

    2009-12-01

    On 14 September 2009, after four years of deliberations, the Indonesian House of Representatives passed the anti-narcotics bill into law. The House says that the law is designed to curb drug trafficking and to save youth from drug use. Critics say the law criminalizes drug users and will have a negative impact on their health.

  11. General aspects concerning strictly meat and fish transmitted parasitic infections

    Directory of Open Access Journals (Sweden)

    Daniele Crotti

    2012-03-01

    Full Text Available All helminths parasitosis transmitted to humans trough ingestion of infested fleshes, where man is definitive host too, are represented by four groups of helminths: the cestodes Dyphyllobothrium spp and Spirometra spp. (Sparganum proliferum is the name of the immature plerocercoid larva, the trematodes Opisthorchis Clonorchis “group” (many could be the genera and species involved, and the nematode Capillaria philippinensis. So, for fishes humans foods (fresh or salted water the control and prevention in veterinary health must be directed to investigation regarding intermediate stages of these parasites in fishes for human alimentation; if present, they must be eliminated. The helminths parasitosis transmitted to humans trough ingestion of infected mammals meats, are represented by taeniasis (Taenia saginata, T. solium and T. saginata asiatica, where man id definitive host and the infection is caused by ingestion of bovine or swine meat, containing larvae of these cestodes, and by trichinellosis, where humans represent a intermediate stage, and the eventual pathology is caused as by adult (acute infection as by larvae (chronic infection of this nematode: usually the meats responsible are infected pork, wild pork or horse (Trichinella spp. Is inside the meats of these animals. So the veterinary control and prophylaxis are necessary to avoid this disease and preventing the infection that could be severe.

  12. Reliability Capacity of Half-Duplex Channels with Strict Deadlines

    DEFF Research Database (Denmark)

    Costa, Rui; Roetter, Daniel Enrique Lucani; Vinhoza, Tiago

    2015-01-01

    of transmissions and provide closed-form upper and lower bounds for this capacity. We show that the reliability capacity converges to the capacity of a classical erasure channel as the deadline constraint is relaxed. In our framework, the effect of feedback is analyzed both in terms of the reliability capacity...... and in terms of its advantages towards the mean number of packets that can be transmitted reliably. Optimal schemes for leveraging feedback are presented and the results show that a judicious use of even a single feedback packet can have a significant impact on the mean performance....

  13. Strict Slaves of Slogans: Response to ''The Social Work Cartel''

    Science.gov (United States)

    Epstein, William M.

    2016-01-01

    The corruption of the social work enterprise is not simply episodic but systemic and long-standing including education, research, governance, and practice. Reform is unlikely since the constituency within the field and outside of it that wishes to change the situation is small and ineffective. The corruption of social work reflects the unfortunate…

  14. Pedagogical Lexicography: Towards a New and Strict Typology ...

    African Journals Online (AJOL)

    The problem is especially severe within so-called pedagogical lexicography. A short panoramic review shows that especially the terms "pedagogical lexicography/dictionaries", "didactic lexicography/dictionaries", "school dictionaries" and "learners' dictionaries" are used with a lot of different meanings that vary from author ...

  15. Strict Anatomical Colocalization of Vitiligo and Elastolytic Granulomas

    Directory of Open Access Journals (Sweden)

    N. Merino de Paz

    2010-02-01

    Full Text Available Vitiligo is the most common depigmenting disorder, with a worldwide occurrence of 0.1–2% in the general population. Multiple conditions have been described colocalized in vitiligo patches, like psoriasis or lichen planus. However, actinic granuloma has not been described in association with vitiligo lesions so far.

  16. Hankel operators and the Dixmier trace on strictly pseudoconvex domains

    Czech Academy of Sciences Publication Activity Database

    Engliš, Miroslav; Zhang, G.

    2010-01-01

    Roč. 15, - (2010), s. 601-622 ISSN 1431-0643 R&D Projects: GA AV ČR IAA100190802 Keywords : Hankel operator * Dixmier trace * Levi form Subject RIV: BA - General Mathematics Impact factor: 0.620, year: 2010 http://www.math.uiuc.edu/documenta/vol-15/18.html

  17. Evaluation of a strict protocol approach in managing women with ...

    African Journals Online (AJOL)

    original ... survived and a further 10 maternal deaths due to complications ..... Unsafe abortion. Administrative factors. Lack of health care facilities including ICU beds'. Barriers to entry. Communication problems. Medical personnel. Inadequate ...

  18. Year Class Coexistence or Competitive Exclusion for Strict Biennials?

    NARCIS (Netherlands)

    Davydova, N.V.; Diekmann, O.; van Gils, Stephanus A.

    2001-01-01

    We consider a discrete time model of semelparous biennial population dynamics. Interactions between individuals are modelled with the aid of an 'environmental'' variable I. The impact on and the sensitivity to the environmental condition is age specific. The main result is that competitive exclusion

  19. Year class coexistence or competitive exclusion for strict biennials?

    NARCIS (Netherlands)

    Davydova, N.V.; Diekmann, O.; van Gils, S.A.

    2003-01-01

    We consider a discrete time model of semelparous biennial population dynamics. Interactions between individuals are modelled with the aid of an ``environmental'' variable I. The impact on and the sensitivity to the environmental condition is age specific. The main result is that competitive

  20. Older adults' experiences and issues with hearing aids in the first six months after hearing aid fitting.

    Science.gov (United States)

    Solheim, Jorunn; Gay, Caryl; Hickson, Louise

    2018-01-01

    This study describes older adults' experiences with a new hearing aid (HA) during the first 6 months after fitting. In a longitudinally designed study, experiences and issues with HA use were assessed at a six-month follow-up appointment in individual structured interviews lasting 30 min. Associations between HA experiences and demographic factors, degree of hearing loss, and an objective measure of HA use (datalogging) were also examined. 181 HA recipients (≥60 years) attending a six-month follow-up appointment. Participants reported an average of 1.4 issues (range 0-5, median = 1, mode = 1) with HA use, the most common pertaining to the earmold (26.5%), sound quality (26.0%) and handling (25.5%). Participants who reported at least one issue had fewer hours of use per day, but were not more likely to be non-users (issues. Most older adults use their HAs regardless of reported issues. However, handling issues and no perceived need may interfere with HA usage among some adults with hearing impairment. Moreover, reported issues were associated with less frequent HA use. Follow-up support is thus important to address issues that may interfere with optimal use.

  1. Current status and future expectation concerning probabilistic risk assessment of NPPs. 1. Features and issues of probabilistic risk assessment methodology

    International Nuclear Information System (INIS)

    Yamashita, Masahiro

    2012-01-01

    Probabilistic risk assessment (PRA) of Nuclear Power Plants (NPPs) could play an important role in assuring safety of NPPs. However PRA had not always effectively used, which was indicated in Japanese government's report on Fukushima Daiichi NPP accident. At the Risk Technical Committee (RTC) of Standards Committee of Atomic Energy Society of Japan, preparation of standards (implementing criteria) focusing on PRA methodology and investigation on basic philosophy for use of PRA had been in progress. Based on activities of RTC, a serial in three articles including this described current status and future expectation concerning probabilistic risk assessment of NPPs. This article introduced features and issues of PRA methodology related to the use of PRA. Features of PRA methodology could be shown as (1) systematic and comprehensive understanding of risk, (2) support of grading approach, (3) identification of effective safety upgrade measures and (4) quantitative understanding of effects of uncertainty. Issues of PRA methodology were (1) extension of PRA application area, (2) upgrade of PRA methodology, (3) quality assurance of PRA, (4) treatment of uncertainty and (5) quantitative evaluation criteria. (T. Tanaka)

  2. [Current Status and Issues of Electronic Information Provision for Risk Minimization: Coordination between Electronic Medicine Notebook and Patient Drug Information].

    Science.gov (United States)

    Orii, Takao

    2018-01-01

     In the collaboration between community pharmacies and hospitals or clinics, the use of electronic medicine notebook may allow information sharing, including among out-of-network hospitals, clinics, and community pharmacies. For risk minimization, mobile or smart phones, which patients always carry with them, should be used as a tool allowing drug information to be accessed at any time. An advantage of the electronic conversion of patient drug information is that it allows patients not only to obtain round-the-clock information on drugs, etc. that they are receiving but also to check patient-oriented information selected and made easier to understand by pharmacists. In the collaboration between community pharmacies and hospitals or clinics, if, for example, patient discharge summaries are conveyed to community pharmacies via electronic medicine notebook, patients will feel reassured about the medical alliance and place more trust in pharmacists overall. This can improve patient drug awareness, thus contributing effectively to risk minimization. Drug information in electronic medicine notebook with 24-h access requires not only patients but also pharmacists to be proactive in its use. In addition, a system to facilitate the proactive use of that information needs to be established. For the electronic conversion of patient drug information and the establishment of a system promoting electronic medicine notebook use, the current status and issues need to be thoroughly examined from the viewpoint of risk communication.

  3. Methods and Issues for the Combined Use of Integral Experiments and Covariance Data: Results of a NEA International Collaborative Study

    Science.gov (United States)

    Salvatores, M.; Palmiotti, G.; Aliberti, G.; Archier, P.; De Saint Jean, C.; Dupont, E.; Herman, M.; Ishikawa, M.; Ivanova, T.; Ivanov, E.; Kim, S.-J.; Kodeli, I.; Manturov, G.; McKnight, R.; Pelloni, S.; Perfetti, C.; Plompen, A. J. M.; Rearden, B. T.; Rochman, D.; Sugino, K.; Trkov, A.; Wang, W.; Wu, H.; Yang, W.-S.

    2014-04-01

    The Working Party on International Nuclear Data Evaluation Cooperation (WPEC) of the Nuclear Science Committee under the Nuclear Energy Agency (NEA/OECD) established a Subgroup (called "Subgroup 33") in 2009 on "Methods and issues for the combined use of integral experiments and covariance data." The first stage was devoted to producing the description of different adjustment methodologies and assessing their merits. A detailed document related to this first stage has been issued. Nine leading organizations (often with a long and recognized expertise in the field) have contributed: ANL, CEA, INL, IPPE, JAEA, JSI, NRG, IRSN and ORNL. In the second stage a practical benchmark exercise was defined in order to test the reliability of the nuclear data adjustment methodology. A comparison of the results obtained by the participants and major lessons learned in the exercise are discussed in the present paper that summarizes individual contributions which often include several original developments not reported separately. The paper provides the analysis of the most important results of the adjustment of the main nuclear data of 11 major isotopes in a 33-group energy structure. This benchmark exercise was based on a set of 20 well defined integral parameters from 7 fast assembly experiments. The exercise showed that using a common shared set of integral experiments but different starting evaluated libraries and/or different covariance matrices, there is a good convergence of trends for adjustments. Moreover, a significant reduction of the original uncertainties is often observed. Using the a-posteriori covariance data, there is a strong reduction of the uncertainties of integral parameters for reference reactor designs, mainly due to the new correlations in the a-posteriori covariance matrix. Furthermore, criteria have been proposed and applied to verify the consistency of differential and integral data used in the adjustment. Finally, recommendations are given for an

  4. Methods and issues for the combined use of integral experiments and covariance data: results of a NEA international collaborative study

    International Nuclear Information System (INIS)

    Salvatores, M.; Palmiotti, G.; Aliberti, G.; McKnight, R.; Archier, P.; De Saint Jean, C.; Dupont, E.; Herman, M.

    2014-01-01

    The Working Party on International Nuclear Data Evaluation Cooperation (WPEC) of the Nuclear Science Committee under the Nuclear Energy Agency (NEA/OECD) established a Subgroup (called 'Subgroup 33') in 2009 on 'Methods and issues for the combined use of integral experiments and covariance data'. The first stage was devoted to producing the description of different adjustment methodologies and assessing their merits. A detailed document related to this first stage has been issued. Nine leading organizations (often with a long and recognized expertise in the field) have contributed: ANL, CEA, INL, IPPE, JAEA, JSI, NRG, IRSN and ORNL. In the second stage a practical benchmark exercise was defined in order to test the reliability of the nuclear data adjustment methodology. A comparison of the results obtained by the participants and major lessons learned in the exercise are discussed in the present paper that summarizes individual contributions which often include several original developments not reported separately. The paper provides the analysis of the most important results of the adjustment of the main nuclear data of 11 major isotopes in a 33-group energy structure. This benchmark exercise was based on a set of 20 well defined integral parameters from 7 fast assembly experiments. The exercise showed that using a common shared set of integral experiments but different starting evaluated libraries and/or different covariance matrices, there is a good convergence of trends for adjustments. Moreover, a significant reduction of the original uncertainties is often observed. Using the a-posteriori covariance data, there is a strong reduction of the uncertainties of integral parameters for reference reactor designs, mainly due to the new correlations in the a-posteriori covariance matrix. Furthermore, criteria have been proposed and applied to verify the consistency of differential and integral data used in the adjustment. Finally, recommendations

  5. Status report on energy recovery from municipal solid waste: technologies, lessons and issues. Information bulletin of the energy task force of the urban consortium

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-01-01

    A review is presented of the lessons learned and issues raised regarding the recovery of energy from solid wastes. The review focuses on technologies and issues significant to currently operating energy recovery systems in the US - waterwall incineration, modular incineration, refuse derived fuels systems, landfill gas recovery systems. Chapters are: Energy Recovery and Solid Waste Disposal; Energy Recovery Systems; Lessons in Energy Recovery; Issues in Energy Recovery. Some basic conclusions are presented concerning the state of the art of energy from waste. Plants in shakedown or under construction, along with technologies in the development stages, are briefly described. Sources of additional information and a bibliography are included. (MCW)

  6. 76 FR 18062 - U.S. Securities; Sale and Issue of Marketable Book-Entry Treasury Bills, Notes, and Bonds; Book...

    Science.gov (United States)

    2011-04-01

    ...[supreg], and Legacy Treasury Direct[supreg]--into which we issue marketable Treasury securities. We... DEPARTMENT OF THE TREASURY Fiscal Service 31 CFR Parts 306, 356, 357, and 363 U.S. Securities; Sale and Issue of Marketable Book-Entry Treasury Bills, Notes, and Bonds; Book-Entry Treasury Bonds...

  7. Identifying Computer-Supported Collaborative Learning (CSCL) Research in Selected Journals Published from 2003 to 2012: A Content Analysis of Research Topics and Issues

    Science.gov (United States)

    Zheng, Lanqin; Huang, Ronghuai; Yu, Junhui

    2014-01-01

    This study aims to identity the emerging research trends in the field of computed-supported collaborative learning (CSCL) so as to provide insights for researchers and educators into research topics and issues for further exploration. This paper analyzed the research topics, methods and technology adoption of CSCL from 2003 to 2012. A total of 706…

  8. Current Status and Issues of Women’s Education in India : A case study of women’s education in Birbhum, West Bengal

    OpenAIRE

    Kawai, Yuka

    2015-01-01

    The purpose of this paper is to clear current status and issues of women’s education in India. So, I have to clear the status in a state and a small area, more concretely. Then, I observe the status in rural area and perform a questionnaire survey by community residents and teachers in Birbhum, West Bengal. I will begin by taking a general view of Women’s Education in whole India. Next, I will consider about Women’s Education in Birbhum, West Bengal. This paper is based on the investigations ...

  9. Family reunification: policies and issues.

    Science.gov (United States)

    Battistella, G

    1995-01-01

    "International standards provide for protection of the family as the fundamental unit of society. However, a consequent right to family reunification for migrants is not sanctioned and continues to be resisted. This article reviews the formulation of the possibility for family reunification as provided for in international and regional standards and by migration policies. It argues that family separation, if inherent in some forms of migration, should not be institutionalized by migration policies and that state sovereignty is limited when dealing with human rights. More specifically it argues that labor migration, as currently developing in Asia, will require appropriate family reunification policies, because it will evolve into some form of settlement." excerpt

  10. School Finance. Trends and Issues.

    Science.gov (United States)

    Hadderman, Margaret, Comp.

    During the past several years, policymakers and practitioners have concentrated their energies on resolving equity/adequacy issues, reforming school tax structures, improving schools' efficiency and cost-effectiveness, developing school-based accountability, and exploring alternative cost-cutting and fundraising strategies. Total expenditures for…

  11. Gender identity development and issues.

    Science.gov (United States)

    Zucker, Kenneth J

    2004-07-01

    This article focuses on the psychosexual development of children and adolescents who have sex-typed behavioral patterns that correspond to the diagnosis of Gender Identity Disorder, as defined in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders. The author provides an update on phenomenology and diagnosis, associated behavior problems, developmental course, biologic and psychosocial influences, and treatment and ethical issues.

  12. ATPA Renewal: Background and Issues

    National Research Council Canada - National Science Library

    Villarreal, M. A

    2008-01-01

    .... The purpose of ATPA is to promote economic growth in the Andean region and to encourage a shift away from dependence on illegal drugs by supporting legitimate economic activities. The ATPA (Title II of P.L. 102-182...

  13. Discriminatory Discipline: Trends and Issues

    Science.gov (United States)

    Whitford, Denise K.; Katsiyannis, Antonis; Counts, Jennifer

    2016-01-01

    Discriminatory discipline has been widely documented for decades, yet little progress has been made to narrow the gap. Due to the long-standing history of discriminatory discipline, current nationwide data, and recent federal initiatives, there is a need for a comprehensive examination of this critical issue. Therefore, we discuss populations…

  14. The Crossmatch/Issue Ratio:  Use of a Novel Quality Indicator and Results of an International Survey on RBC Crossmatching and Issuing Practices

    DEFF Research Database (Denmark)

    Yazer, Mark H; Alcantara, Ramir; Beizai, Pouneh

    2016-01-01

    , and the mean ± SD was 1.30 ± 0.34. There was no difference in C/I ratios between services that use the electronic or serologic crossmatch techniques (P = .49). The ratio was the same at the four sites that crossmatch RBCs at the time of issue compared with the time of order receipt (mean ± SD, 1.11 ± 0.09 vs......OBJECTIVES: To understand the worldwide scope of RBC crossmatching and issuing practices and measure efficiency using a novel quality indicator, the crossmatch/issue (C/I) ratio. METHODS: An electronic survey was disseminated to hospital transfusion services collecting details about RBC...

  15. The use of mineral resources and issues of harmonization between spatial plans for the mining areas in Serbia with other strategic documents

    Directory of Open Access Journals (Sweden)

    Petrić Jasna

    2011-01-01

    Full Text Available Growing development needs and requirements for mineral resources endorsed by the contemporary society reopen the issues of mineral resources finitude and effects that mineral industry imposes on the global scene. Mining is certainly among the activities which raise numerous environmental and social concerns being enhanced by continuous demand for new exploitation areas. Experience supports the need for continuous process of planning in the mining areas and development of extensive research, both fundamental and applied. With particular focus on spatial plans for the mining areas in Serbia, this paper addresses current mining regulatory framework and issue of harmonization between spatial plans for the mining areas with other pertinent strategic documents on environmental and social protection. Regardless they have been prescriptive or legally binding, fundamental principles of these strategic documents serve as guidance towards sustainable development in the mining sector under the new institutional, organization and economic settings.

  16. Radioactive waste management practices and issues in developing countries. Proceedings of a seminar held in Beijing, China, 10-14 October 1994

    International Nuclear Information System (INIS)

    1995-12-01

    Radioactive waste is generated from the production of nuclear energy and from the use of radioactive materials in industrial applications, research and medicine. The importance of safe management of radioactive waste for the protection of human health and the environment has long been recognized and considerable experience has been gained in this field. While this programme is developing and various related Safety Series publications are becoming available, it is important to compare the existing national waste management regulations, organization, technologies and methods with internationally accepted requirements and practices. In response to the growing interest in this area, the IAEA, in co-operation with the Government of the People's Republic of China, held a Seminar on Radioactive Waste Management Practices and Issues in Developing Countries at Beijing from 10 to 14 October 1994. Refs, figs and tabs

  17. Basic concepts and issues: a primer on distribution and sales representative agreements in the medical device and durable medical equipment industries.

    Science.gov (United States)

    Burow, Heiko E; Kolls, Raymond C

    2006-01-01

    Counsel for a manufacturer of medical devices or durable medical equipment must have working knowledge of various legal disciplines to draft contracts with intermediaries (sales representatives and distributors) for the marketing and sale of the manufacturer's products. If the manufacturer wishes to sell its products abroad, counsel must become familiar with the laws and business practices of the target country, and methods of gaining access to the foreign market. This Article gives readers an overview of the applicable legal principles, under U.S. and foreign laws, in the areas of agency, contracts, healthcare regulation, consumer protection, intellectual property protection, and dealer protection. To aid counsel in drafting intermediary agreements, specific contractual terms and issues are explored in depth, including: appointment clauses, performance provisions, provisions concerning pricing and payment, protective clauses (shielding the manufacturer from liability), term and termination provisions, independent contractor clauses, export control clauses, recordkeeping and audit provisions, choice of law clauses, and dispute resolution clauses.

  18. Origins of the Electronic Apex Locator - Achieving Success with Strict Adherence to Business.

    Science.gov (United States)

    Gutmann, James L

    2017-01-01

    Current history would have you believe that the evolution and development of the electronic apex locator for use during root canal procedures emanated from the work of Suzuki in 1942, which was developed as a product by Sunada in 1962. Yes, this is partly correct, however the concept of using electrical means to locate the ends of root canals was brought to the dental profession as early as 1918 by Dr. Levitt Ellsworth Custer, which was not addressed until Suzuki revisited Custer's concepts. This contribution was only one of the many that Custer proffered as he championed the use of electricity in dentistry. Copyright American Academy of the History of Dentistry.

  19. Antithrombotic properties of aspirin and resistance to aspirin: beyond strictly antiplatelet actions

    OpenAIRE

    Undas, Anetta; Brummel-Ziedins, Kathleen E.; Mann, Kenneth G.

    2007-01-01

    Aspirin is effective in the prevention of cardiovascular events in high-risk patients. The primary established effect of aspirin on hemostasis is to impair platelet aggregation via inhibition of platelet thromboxane A2 synthesis, thus reducing thrombus formation on the surface of the damaged arterial wall. Growing evidence also indicates that aspirin exerts additional antithrombotic effects, which appear to some extent unrelated to platelet thromboxane A2 production. Aspirin can reduce thromb...

  20. Effect of scanner acoustic background noise on strict resting-state fMRI

    Directory of Open Access Journals (Sweden)

    C. Rondinoni

    2013-04-01

    Full Text Available Functional MRI (fMRI resting-state experiments are aimed at identifying brain networks that support basal brain function. Although most investigators consider a ‘resting-state' fMRI experiment with no specific external stimulation, subjects are unavoidably under heavy acoustic noise produced by the equipment. In the present study, we evaluated the influence of auditory input on the resting-state networks (RSNs. Twenty-two healthy subjects were scanned using two similar echo-planar imaging sequences in the same 3T MRI scanner: a default pulse sequence and a reduced “silent” pulse sequence. Experimental sessions consisted of two consecutive 7-min runs with noise conditions (default or silent counterbalanced across subjects. A self-organizing group independent component analysis was applied to fMRI data in order to recognize the RSNs. The insula, left middle frontal gyrus and right precentral and left inferior parietal lobules showed significant differences in the voxel-wise comparison between RSNs depending on noise condition. In the presence of low-level noise, these areas Granger-cause oscillations in RSNs with cognitive implications (dorsal attention and entorhinal, while during high noise acquisition, these connectivities are reduced or inverted. Applying low noise MR acquisitions in research may allow the detection of subtle differences of the RSNs, with implications in experimental planning for resting-state studies, data analysis, and ergonomic factors.

  1. Thermaerobacter litoralis sp. nov., a strictly aerobic and thermophilic bacterium isolated from a coastal hydrothermal field

    DEFF Research Database (Denmark)

    Tanaka, Reiji; Kawaichi, Satoshi; Nishimura, Hiroshi

    2006-01-01

    A novel thermophilic bacterium, strain KW1T, was isolated from a coastal hydrothermal field on the Satsuma Peninsula, Kagoshima Prefecture, Japan. The variably Gram-stained cells were motile rods with flagella, did not form spores and proliferated at 52-78°C (optimum, 70°C), pH 5-8 (optimum, pH 7...

  2. Assessment of different management systems in an area of cerrado sensu strict

    Directory of Open Access Journals (Sweden)

    Flávia Nascimento de Souza

    2011-03-01

    Full Text Available This study aims to evaluate the effect of different management systems on the floristic composition and diversity of a fragment of Cerrado sensu stricto vegetation located in Brasilândia de Minas (MG, eleven years after interventions. In 1997, 30 plots were installed in the study site, in a random block design, consisting of ten treatments with three replications: 50%, 60%, 70% and 80% removal of the basal area, involving 20% reduction and increase in the De Liocourt quotient value; clear cutting and control treatment. Prior to treatment installation, an inventory was compiled of original vegetation. In 2004 and 2008 further inventories were produced. It was observed that interventions in the relevant Cerrado area led to changes in the floristic composition and diversity of local vegetation, yet these changes were also observed in undisturbed areas which had not been subjected to management plans.

  3. Residuated Logics based on Strict Triangular Norms with an Involutive Negation

    Czech Academy of Sciences Publication Activity Database

    Cintula, Petr; Klement, E.P.; Mesiar, R.; Navara, M.

    2006-01-01

    Roč. 52, č. 3 (2006), s. 269-282 ISSN 0942-5616 R&D Projects: GA MŠk 1M0545 Grant - others:Grantová agentura SR(SK) VEGA 1/3006/06; COSPAL(EU) IST-2004-71567 Keywords : fuzzy logic * involutive negation * BL-algebra * variety * triangular norm * hamacher product Subject RIV: BA - General Mathematics Impact factor: 0.629, year: 2006

  4. Occurrence and Species Distribution of Strictly Anaerobic Bacterium Pectinatus in Brewery Bottling Halls

    Czech Academy of Sciences Publication Activity Database

    Matoulková, D.; Kosař, K.; Slabý, M.; Sigler, Karel

    2012-01-01

    Roč. 70, č. 4 (2012), s. 262-267 ISSN 0361-0470 Institutional support: RVO:61388971 Keywords : Beer spoilage * Biofilm * Conveyor belt Subject RIV: EE - Microbiology, Virology Impact factor: 1.000, year: 2012

  5. Maritime Transport of Environmentally Damaging Materials - A Balance Between Absolute Freedom and Strict Prohibition

    Directory of Open Access Journals (Sweden)

    Thaqal S. Al-Ajmi

    2007-06-01

    Full Text Available This study is intended to balance the rights of free navigation in all of its forms whether in the high seas or in the territorial waters of other States by resorting to the right of innocent passage and right of transit passage, which is enjoyable by all States and the obligation to protect the environment from any damaging materials as imposed upon all States at the same time, when such damaging materials are shipped from one State to another via seas or oceans. According to this study, which presented many evidence from international law and regional and even national practice, the obligation to protect the environment supersedes the right of free navigation, therefore restricting the right to ship or transport materials that could cause damage to the environment.

  6. Fermentation of animal components in strict carnivores: a comparative study with cheetah fecal inoculum

    NARCIS (Netherlands)

    Depauw, S.; Bosch, G.; Hesta, M.; Whitehouse-Tedd, K.; Hendriks, W.H.; Kaandorp, J.; Janssens, G.P.J.

    2012-01-01

    The natural diet of felids contains highly digestible animal tissues but also fractions resistant to small intestinal digestion, which enter the large intestine where they may be fermented by the resident microbial population. Little information exists on the microbial degradability of animal

  7. Towards the strict legal enforcement of best practice principles in oil ...

    African Journals Online (AJOL)

    The article found that environmental regulations are often ineffective because they are substantively inadequate and/or inadequately enforced. This accounts for environmental pollution arising from oil and gas industry. The article highlighted some of the best approaches to achieving high environmental performance in the ...

  8. Is it necessary to strictly diagnose fibromyalgia syndrome in patients with chronic widespread pain?

    Science.gov (United States)

    On, Arzu Yagiz; Aykanat, Dilek; Atamaz, Funda Calis; Eyigor, Can; Kocanogullari, Hayriye; Oksel, Fahrettin

    2015-08-01

    The applicability of the American College of Rheumatology (ACR) 1990 and 2010 criteria for the diagnosis of fibromyalgia syndrome (FMS) was determined in 284 patients with chronic widespread pain (CWP) including those with regional and systemic painful disorders. On the basis of initial evaluation, patients were classified into three groups. Group 1, those without any comorbid disease (N = 105), group 2, those having regional non-inflammatory painful disorders (N = 104), and group 3, those with a diagnosis of an inflammatory rheumatic disease (N = 75). Overall, 65 % of the patients fulfilled the 1990 criteria, while 94 % of them fulfilled the 2010 criteria. Almost all of the patients (97 %) with CWP did meet at least one of the criteria set, regardless of whether they have accompanying painful disorders. Widespread pain index (WPI), symptom severity scale (SS), and fibromyalgia impact questionnaire (FIQ) scores were found to be significantly higher in the patients who satisfied the 1990 criteria than those who did not (P classification of CWP to provide guidance to clinicians in selecting effective therapies.

  9. How strict is galactose restriction in adults with galactosaemia? International practice

    NARCIS (Netherlands)

    Adam, Siddig Momin; Akroyd, R.; Bernabei, S.; Bollhalder, S.; Boocock, S.; Burlina, A.; Coote, T.; Corthouts, K.; Dalmau, Judith; Dawson, S.; Defourny, S.; Meyer, A.; Desloovere, A.; Devlin, Y.; Diels, M.; Dokoupil, K.; Donald, S.; Evans, S.; Fasan, I.; Ferguson, C.; Ford, S.; Forga, M.; Gallo, G.; Grünert, S.C.; Heddrich-Ellerbrok, M.; Heidenborg, C.; Jonkers, C.F.; Lefebure, K.; Luyten, K.; MacDonald, A.; Meyer, U.; Micciche, A.; Müller, E.; Portnoi, P.; Ripley, S.; Robert, C.M.; Robertson, L.V.; Rosenbaum-Fabian, S.; Sahm, K.; Schultz, Erica S; Singleton, K.; Sjöqvist, E.; Stoelen, L.; Terry, A.; Thompson, S.; Timmer, C.; Vande Kerckhove, K.; van den Ploeg, L.; Van Driessche, M.; van Rijn, M.; van Teeffelen-Heithoff, A.; Vitoria, I.; Voillot, C.; Wenz, J.; Westbrook, M.; Wildgoose, J.; Zweers, H.

    2015-01-01

    Dietary management of 418 adult patients with galactosaemia (from 39 centres/12 countries) was compared. All centres advised lactose restriction, 6 restricted galactose from galactosides. ±. fruits and vegetables and 12 offal. 38% (n. =. 15) relaxed diet by: 1) allowing traces of lactose in

  10. How strict is galactose restriction in adults with galactosaemia? International practice

    NARCIS (Netherlands)

    Adam, S.; Akroyd, R.; Bernabei, S.; Bollhalder, S.; Boocock, S.; Burlina, A.; Coote, T.; Corthouts, K.; Dalmau, J.; Dawson, S.; Defourny, S.; de Meyer, A.; Desloovere, A.; Devlin, Y.; Diels, M.; Dokoupil, K.; Donald, S.; Evans, S.; Fasan, I.; Ferguson, C.; Ford, S.; Forga, M.; Gallo, G.; Grünert, S. C.; Heddrich-Ellerbrok, M.; Heidenborg, C.; Jonkers, C.; Lefebure, K.; Luyten, K.; Macdonald, A.; Meyer, U.; Micciche, A.; Müller, E.; Portnoi, P.; Ripley, S.; Robert, M.; Robertson, L. V.; Rosenbaum-Fabian, S.; Sahm, K.; Schultz, S.; Singleton, K.; Sjöqvist, E.; Stoelen, L.; Terry, A.; Thompson, S.; Timmer, C.; Vande Kerckhove, K.; van der Ploeg, L.; van Driessche, M.; van Rijn, M.; van Teeffelen-Heithoff, A.; Vitoria, I.; Voillot, C.; Wenz, J.; Westbrook, M.; Wildgoose, J.; Zweers, H.

    2015-01-01

    Dietary management of 418 adult patients with galactosaemia (from 39 centres/12 countries) was compared. All centres advised lactose restriction, 6 restricted galactose from galactosides +/- fruits and vegetables and 12 offal. 38% (n = 15) relaxed diet by: 1) allowing traces of lactose in

  11. How strict is galactose restriction in adults with galactosaemia? International practice

    NARCIS (Netherlands)

    Adam, S.; Akroyd, R.; Bernabei, S.; Bollhalder, S.; Boocock, S.; Burlina, A.; Coote, T.; Corthouts, K.; Dalmau, J.; Dawson, S.; Defourny, S.; Meijer, A; Desloovere, A.; Devlin, Y.; Diels, M.; Dokoupil, K.; Donald, S.; Evans, S.; Fasan, I.; Ferguson, C.; Ford, S.; Forga, M.; Gallo, G.; Grunert, S.C.; Heddrich-Ellerbrok, M.; Heidenborg, C.; Jonkers, C.; Lefebure, K.; Luyten, K.; Macdonald, A.; Meyer, U.; Micciche, A.; Muller, E.; Portnoi, P.; Ripley, S.; Robert, M.; Robertson, L.V.; Rosenbaum-Fabian, S.; Sahm, K.; Schultz, S.; Singleton, K.; Sjoqvist, E.; Stoelen, L.; Terry, A.; Thompson, S.; Timmer, C.; Kerckhove, K. Vande; Ploeg, L. van der; Driessche, M. Van; Rijn, M. van de; Teeffelen-Heithoff, A. van; Vitoria, I.; Voillot, C.; Wenz, J.; Westbrook, M.; Wildgoose, J.; Zweers, H.E.

    2015-01-01

    Dietary management of 418 adult patients with galactosaemia (from 39 centres/12 countries) was compared. All centres advised lactose restriction, 6 restricted galactose from galactosides +/- fruits and vegetables and 12 offal. 38% (n=15) relaxed diet by: 1) allowing traces of lactose in manufactured

  12. How strict is galactose restriction in adults with galactosaemia? International practice

    NARCIS (Netherlands)

    Adam, S.; Akroyd, R.; Bernabei, S.; Bollhalder, S.; Boocock, S.; Burlina, A.; Coote, T.; Corthouts, K.; Dalmau, J.; Dawson, S.; Defourny, S.; De Meyer, A.; Desloovere, A.; Devlin, Y.; Diels, M.; Dokoupil, K.; Donald, S.; Evans, S.; Fasan, I.; Ferguson, C.; Ford, S.; Forga, M.; Gallo, G.; Gruenert, S. C.; Heddrich-Ellerbrok, M.; Heidenborg, C.; Jonkers, C.; Lefebure, K.; Luyten, K.; MacDonald, A.; Meyer, U.; Micciche, A.; Mueller, E.; Portnoi, P.; Ripley, S.; Robert, M.; Robertson, L. V.; Rosenbaum-Fabian, S.; Sahm, K.; Schultz, S.; Singleton, K.; Sjoqvist, E.; Stoelen, L.; Terry, A.; Thompson, S.; Timmer, C.; Vande Kerckhove, K.; van der Ploeg, L.; Van Driessche, M.; van Rijn, M.; van Teeffelen-Heithoff, A.; Vitoria, I.; Voillot, C.; Wenz, J.; Westbrook, M.; Wildgoose, J.; Zweers, H.

    Dietary management of 418 adult patients with galactosaemia (from 39 centres/12 countries) was compared. All centres advised lactose restriction, 6 restricted galactose from galactosides +/- fruits and vegetables and 12 offal. 38% (n = 15) relaxed diet by: 1) allowing traces of lactose in

  13. The strict liability principle in antidoping rules and the human rights of athletes: an approach critical

    Directory of Open Access Journals (Sweden)

    R.C. Cunha

    2008-01-01

    Full Text Available Back Ground: the human lives in search of overrun at all levels, whether professional, emotional or in their interpersonal relationships. In the middle of sports this search becomes more visible, because hundredths of seconds can make the difference between the podium and the failure. Journals at any moment announces a new case of a positive doping in several sports. Objective: analyse the processes judged for doping in the STJD of the Brazilian athletism and verify if the pronounced sentences are in accordance with the Brazilian Constitution and with the Universal Declaration of the Human Rights. Materials and Methods: 18 cases were reviewed by the use of prohibited substance, between the years 2003 to 2006 by the STJD of Athletism. Results: of the 18 cases examined only 3 were acquitted by the STJD, however, these three, two have met suspension for two years, in order that WADA, not satisfied with the results asked the International Federation (IAAF to analyze them, and after guided them to the Court of Arbitration Sports (CAS. Conclusion: the rule of objective responsibility are not in accordance with the Brazilian Constitution and with the Universal Declaration of the Human Rights, leading athletes to respond irrespective proven their guilt.

  14. Strict limit on CPT violation from polarization of γ-ray bursts.

    Science.gov (United States)

    Toma, Kenji; Mukohyama, Shinji; Yonetoku, Daisuke; Murakami, Toshio; Gunji, Shuichi; Mihara, Tatehiro; Morihara, Yoshiyuki; Sakashita, Tomonori; Takahashi, Takuya; Wakashima, Yudai; Yonemochi, Hajime; Toukairin, Noriyuki

    2012-12-14

    We report the strictest observational verification of CPT invariance in the photon sector, as a result of γ-ray polarization measurement of distant gamma-ray bursts (GRBs), which are the brightest stellar-sized explosions in the Universe. We detected γ-ray polarization of three GRBs with high significance levels, and the source distances may be constrained by a well-known luminosity indicator for GRBs. For the Lorentz- and CPT-violating dispersion relation E(±)(2) = p(2) ± 2ξp(3)/M(Pl), where ± denotes different circular polarization states of the photon, the parameter ξ is constrained as |ξ|

  15. Scurvy in the present times: vitamin C allergy leading to strict fast food diet.

    Science.gov (United States)

    Shaath, Tarek; Fischer, Ryan; Goeser, Megan; Rajpara, Anand; Aires, Daniel

    2016-01-15

    Scurvy results from a deficiency of vitamin C, a nutrient otherwise known as ascorbic acid. Today, scurvy is rare yet emerges in select patients. The patient reported herein developed scurvy secondary to deliberate avoidance of vitamin C-rich foods. Classic cutaneous manifestations of scurvy include follicular hyperkeratosis and perifollicular hemorrhage encompassing coiled "corkscrew" hairs and hairs bent into "swan-neck" deformities. Ecchymoses, purpura, and petechiae are also characteristically prominent. Classic oral abnormalities include erythematous, swollen gingivae that hemorrhage from subtle microtrauma.Subungual linear splinter hemorrhages may also manifest as a sign of the disease. To establish the diagnosis requirements include characteristic physical exam findings, evidence of inadequate dietary intake, and rapid reversal of symptoms upon supplementation. Although unnecessary for diagnosis, histological findings demonstrate perifollicular inflammation and hemorrhage, fibrosis, and hyperkeratosis, amongst dilated hair follicles and keratin plugging. Although citrus fruit allergies have been historically documented, ascorbic acid has not been previously reported as an allergen. Although lacking absolute certainty, this report suggests a presumed case of ascorbic acid allergy based on patient history and favorable response to ascorbic acid desensitization therapy.

  16. Response of molars and non-molars to a strict supragingival control in periodontal patients

    Directory of Open Access Journals (Sweden)

    Patrícia Daniela Melchiors Angst

    2013-02-01

    Full Text Available The posterior position in the arches is one of the factors that underlies the poor prognosis of molar teeth (M. It is speculated that M do not benefit from the oral hygiene routine as well as non-molars (NM do. This study evaluated the response of M and NM to supragingival control during a 6-month period in 25 smokers (S and 25 never-smokers (NS with moderate-to-severe periodontitis. One calibrated examiner assessed visible plaque (VPI and gingival bleeding (GBI indexes, periodontal probing depth (PPD, bleeding on probing (BOP, and clinical attachment loss (CAL at days 0 (baseline, 30 and 180. At baseline, M showed significantly higher mean values of VPI (p = 0.017 and PPD (p < 0.001 compared with NM; CAL was also greater in M (p < 0.001 and was affected by smoking (p = 0.007. The reductions obtained for periodontal indicators at day 180 showed similar responses between M and NM. For CAL, M (NS 0.57 ± 0.50; S 0.67 ± 0.64 and NM (NS 0.38 ± 0.23; S 0.50 ± 0.33 reached an almost significant difference (p = 0.05. Smoking did not influence the response to treatment. Multilevel analysis revealed that, only for PDD reductions, the interaction between sites, teeth and patient was significant (p < 0.001. It was concluded that M benefit from an adequate regimen of supragingival biofilm control; therefore, supragingival condition should be considered in the prognosis of molar teeth.

  17. Pseudouridine synthase 1: a site-specific synthase without strict sequence recognition requirements

    Science.gov (United States)

    Sibert, Bryan S.; Patton, Jeffrey R.

    2012-01-01

    Pseudouridine synthase 1 (Pus1p) is an unusual site-specific modification enzyme in that it can modify a number of positions in tRNAs and can recognize several other types of RNA. No consensus recognition sequence or structure has been identified for Pus1p. Human Pus1p was used to determine which structural or sequence elements of human tRNASer are necessary for pseudouridine (Ψ) formation at position 28 in the anticodon stem-loop (ASL). Some point mutations in the ASL stem of tRNASer had significant effects on the levels of modification and compensatory mutation, to reform the base pair, restored a wild-type level of Ψ formation. Deletion analysis showed that the tRNASer TΨC stem-loop was a determinant for modification in the ASL. A mini-substrate composed of the ASL and TΨC stem-loop exhibited significant Ψ formation at position 28 and a number of mutants were tested. Substantial base pairing in the ASL stem (3 out of 5 bp) is required, but the sequence of the TΨC loop is not required for modification. When all nucleotides in the ASL stem other than U28 were changed in a single mutant, but base pairing was retained, a near wild-type level of modification was observed. PMID:22102571

  18. The Strict Liability Principle and the Human Rights of the Athlete in Doping Cases

    NARCIS (Netherlands)

    J.W. Soek

    2006-01-01

    textabstractAthletes who achieve extraordinary feats on the pitch stir up the imagination and enjoy a unique position within society. However, laurels received one day, may be just as quickly snatched back the next if it becomes known that the athlete achieved his or her exceptional performance

  19. Non-financial reporting beyond the strict minimum: is the workforce a well-informed stakeholder?

    NARCIS (Netherlands)

    Cremers, J.

    2013-01-01

    This working paper by Jan Cremers of the Amsterdam Institute of Advanced Labour Studies summarises the results of an inquiry by the SEEurope network on the current legal framework and practices in 28 European countries regarding non-financial and sustainability-related reporting by European

  20. Pay attention : strict assessors, rising rates make property taxes a field to watch

    International Nuclear Information System (INIS)

    Olstad, K.; Nelson, B.

    2000-01-01

    Some important information regarding the changing property tax regime for members within Alberta's oil and gas community were discussed. It was suggested that proper attention to property taxes, which are considered to be the third highest fixed cost within the industry, can give companies many advantages. New regulations in the taxation system in Alberta will affect linear property such as flowlines and pipelines, gas plants and compressor stations as well as petrochemical and fertilizer plants. Instead of relying on self-reporting, the provincial government will use data filed with the Alberta Energy and Utilities Board (AEUB). Under this new system, a company will have to take real steps to deactivate an asset. This will mean added expense and management time. In some cases companies will choose to avoid the additional steps and pay a higher active rate for assets producing no revenue. Another new change will lie in the fact that companies will have to pay close attention to the deadline of October 31 for filing changes of status with the AEUB, including filing changes in machinery and equipment. February 15 will be the winter deadline for companies to appeal any assessments. Another major tax change is that the province will make linear assessment in the name of the licensee of a well or pipeline. The Alberta government is also considering offsetting the adjustments of the tax rate. 1 fig

  1. Strictly NO3- Nutrition Alleviates Iron Deficiency Chlorosis in Arabidopsis thaliana Plants

    Directory of Open Access Journals (Sweden)

    Najoua Msilini

    2014-03-01

    Full Text Available The effects of NO3- nutrition on iron deficiency responses were investigated in Arabidopsis thaliana. Plants were grown with or without 5 µM Fe, and with NO3- alone or a mixture of NO3- and NH4+. The results indicated that, NO3- nutrition induced higher dry matter production, regardless the Fe concentration. Fe deficiency reduced growth activity, photosynthetic pigment concentration and Fe content of plants, whatever the N forms. This decrease was more pronounced in plants grown with mixed N source; those plants presented the highest EL and MDA and anthocyanin contents compared to plants grown under Fe sufficient conditions. In iron free-solutions, with NO3- as the sole nitrogen source, enhanced FC-R activity in the roots was observed. However, in the presence of NH4+, plants displayed some decrease in in FC-R and PEPC activities. The presence of NH4+ modified typical Fe stress responses in Arabidopsis thaliana plants.

  2. Composite Intelligent Learning Control of Strict-Feedback Systems With Disturbance.

    Science.gov (United States)

    Xu, Bin; Sun, Fuchun

    2018-02-01

    This paper addresses the dynamic surface control of uncertain nonlinear systems on the basis of composite intelligent learning and disturbance observer in presence of unknown system nonlinearity and time-varying disturbance. The serial-parallel estimation model with intelligent approximation and disturbance estimation is built to obtain the prediction error and in this way the composite law for weights updating is constructed. The nonlinear disturbance observer is developed using intelligent approximation information while the disturbance estimation is guaranteed to converge to a bounded compact set. The highlight is that different from previous work directly toward asymptotic stability, the transparency of the intelligent approximation and disturbance estimation is included in the control scheme. The uniformly ultimate boundedness stability is analyzed via Lyapunov method. Through simulation verification, the composite intelligent learning with disturbance observer can efficiently estimate the effect caused by system nonlinearity and disturbance while the proposed approach obtains better performance with higher accuracy.

  3. Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling.

    Science.gov (United States)

    Ermilov, Alexandre N; Kumari, Archana; Li, Libo; Joiner, Ariell M; Grachtchouk, Marina A; Allen, Benjamin L; Dlugosz, Andrzej A; Mistretta, Charlotte M

    2016-11-01

    For homeostasis, lingual taste papilla organs require regulation of epithelial cell survival and renewal, with sustained innervation and stromal interactions. To investigate a role for Hedgehog/GLI signaling in adult taste organs we used a panel of conditional mouse models to manipulate GLI activity within epithelial cells of the fungiform and circumvallate papillae. Hedgehog signaling suppression rapidly led to taste bud loss, papilla disruption, and decreased proliferation in domains of papilla epithelium that contribute to taste cells. Hedgehog responding cells were eliminated from the epithelium but retained in the papilla stromal core. Despite papilla disruption and loss of taste buds that are a major source of Hedgehog ligand, innervation to taste papillae was maintained, and not misdirected, even after prolonged GLI blockade. Further, vimentin-positive fibroblasts remained in the papilla core. However, retained innervation and stromal cells were not sufficient to maintain taste bud cells in the context of compromised epithelial Hedgehog signaling. Importantly taste organ disruption after GLI blockade was reversible in papillae that retained some taste bud cell remnants where reactivation of Hedgehog signaling led to regeneration of papilla epithelium and taste buds. Therefore, taste bud progenitors were either retained during epithelial GLI blockade or readily repopulated during recovery, and were poised to regenerate taste buds once Hedgehog signaling was restored, with innervation and papilla connective tissue elements in place. Our data argue that Hedgehog signaling is essential for adult tongue tissue maintenance and that taste papilla epithelial cells represent the key targets for physiologic Hedgehog-dependent regulation of taste organ homeostasis. Because disruption of GLI transcriptional activity in taste papilla epithelium is sufficient to drive taste organ loss, similar to pharmacologic Hedgehog pathway inhibition, the findings suggest that taste alterations in cancer patients using systemic Hedgehog pathway inhibitors result principally from interruption of signaling activity in taste papillae.

  4. Sponge-associated bacteria are strictly maintained in two closely related but geographically distant sponge hosts.

    Science.gov (United States)

    Montalvo, Naomi F; Hill, Russell T

    2011-10-01

    The giant barrel sponges Xestospongia muta and Xestospongia testudinaria are ubiquitous in tropical reefs of the Atlantic and Pacific Oceans, respectively. They are key species in their respective environments and are hosts to diverse assemblages of bacteria. These two closely related sponges from different oceans provide a unique opportunity to examine the evolution of sponge-associated bacterial communities. Mitochondrial cytochrome oxidase subunit I gene sequences from X. muta and X. testudinaria showed little divergence between the two species. A detailed analysis of the bacterial communities associated with these sponges, comprising over 900 full-length 16S rRNA gene sequences, revealed remarkable similarity in the bacterial communities of the two species. Both sponge-associated communities include sequences found only in the two Xestospongia species, as well as sequences found also in other sponge species and are dominated by three bacterial groups, Chloroflexi, Acidobacteria, and Actinobacteria. While these groups consistently dominate the bacterial communities revealed by 16S rRNA gene-based analysis of sponge-associated bacteria, the depth of sequencing undertaken in this study revealed clades of bacteria specifically associated with each of the two Xestospongia species, and also with the genus Xestospongia, that have not been found associated with other sponge species or other ecosystems. This study, comparing the bacterial communities associated with closely related but geographically distant sponge hosts, gives new insight into the intimate relationships between marine sponges and some of their bacterial symbionts.

  5. Highly demanding resistive vibration exercise program is tolerated during 56 days of strict bed-rest

    NARCIS (Netherlands)

    Rittweger, J.; Belavy, D.; Hunek, P.; Gast, U.; Boerst, H.; Feilcke, B.; Armbrecht, G.; Mulder, E.; Schubert, H.; Richardson, C.; Haan, A. de; Stegeman, D.F.; Schiessl, H.; Felsenberg, D.

    2006-01-01

    Several studies have tried to find countermeasures against musculoskeletal de-conditioning during bed-rest, but none of them yielded decisive results. We hypothesised that resistive vibration exercise (RVE) might be a suitable training modality. We have therefore carried out a bed-rest study to

  6. Highly demanding resistive vibration exercise program is tolerated during 56 days of strict bed-rest.

    NARCIS (Netherlands)

    Rittweger, J.; Belavy, D.; Hunek, P.; Gast, U.; Boerst, H.; Feilcke, B.; Armbrecht, G.; Mulder, E.R.; Schubert, H.; Richardson, C.; de Haan, A.; Stegeman, D.F.; Schiessl, H.; Felsenberg, D.

    2006-01-01

    Several studies have tried to find countermeasures against musculoskeletal de-conditioning during bed rest, but none of them yielded decisive results. We hypothesised that resistive vibration exercise (RVE) might be a suitable training modality. We have therefore carried out a bed-rest study to

  7. Strict molecular sieving over electrodeposited 2D-interspacing-narrowed graphene oxide membranes.

    Science.gov (United States)

    Qi, Benyu; He, Xiaofan; Zeng, Gaofeng; Pan, Yichang; Li, Guihua; Liu, Guojuan; Zhang, Yanfeng; Chen, Wei; Sun, Yuhan

    2017-10-10

    To separate small molecules/species, it's crucial but still challenging to narrow the 2D-interspacing of graphene oxide (GO) membranes without damaging the membrane. Here the fast deposition of ultrathin, defect-free and robust GO layers is realized on porous stainless steel hollow fibers (PSSHFs) by a facile and practical electrophoresis deposition (ED) method. In this approach, oxygen-containing groups of GO are selectively reduced, leading to a controlled decrease of the 2D channels of stacked GO layers. The resultant ED-GO@PSSHF composite membranes featured a sharp cutoff between C2 (ethane and ethene) and C3 (propane and propene) hydrocarbons and exhibited nearly complete rejections for the smallest alcohol and ion in aqueous solutions. This demonstrates the versatility of GO based membranes for the precise separation of various types of mixtures. At the same time, a robust mechanical strength of the ED-GO@PSSHF membrane is also achieved due to the enhanced interaction at GO/support and GO/GO interfaces.Producing graphene oxide membranes with narrow channels is desirable for small molecule separations, but methods to narrow the 2D spacing typically result in membrane damage. Here the authors exploit electrophoresis-deposition to prepare GO membranes that are reduced in situ, leading to narrow and uniform 2D channels.

  8. An Ultra-light PRNG Passing Strict Randomness Tests and Suitable for Low Cost Tags

    Directory of Open Access Journals (Sweden)

    OZCANHAN, M. H.

    2016-08-01

    Full Text Available A pseudo-random number generator for low-cost RFID tags is presented. The scheme is simple, sequential and secure, yet has a high performance. Despite its lowest hardware complexity, our proposal represents a better alternative than previous proposals for low-cost tags. The scheme is based on the well-founded pseudo random number generator, Mersenne Twister. The proposed generator takes low-entropy seeds extracted from a physical characteristic of the tag and produces outputs that pass popular randomness tests. Contrarily, previous proposal tests are based on random number inputs from a popular online source, which are simply unavailable to tags. The high performance and satisfactory randomness of present work are supported by extensive test results and compared with similar previous works. Comparison using proven estimation formulae indicates that our proposal has the best hardware complexity, power consumption, and the least cost.

  9. Proper feedback compensators for a strictly proper plant by polynominal equations

    Czech Academy of Sciences Publication Activity Database

    Callier, F. M.; Kraffer, Ferdinand

    2005-01-01

    Roč. 15, č. 4 (2005), s. 101-115 ISSN 1641-876X Institutional research plan: CEZ:AV0Z10750506 Keywords : linear time-invariant feedback control systems * polynomial matrix systems * row-column-reduced polynomial Subject RIV: BC - Control Systems Theory

  10. Adhésion à l'OMC : des conditions trop strictes ? | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    31 janv. 2011 ... L'adhésion comporte des coûts et des risques, déclare Siphana. Mais à tout considérer, les avantages dépassent les inconvénients. Nous avons choisi de ne pas tergiverser et de nous joindre au peloton même si nous sommes au nombre des PMA. Pour nous, c'est une question de survie. La compassion ...

  11. Oxidized LDL Is Strictly Limited to Hyperthyroidism Irrespective of Fat Feeding in Female Sprague Dawley Rats

    Directory of Open Access Journals (Sweden)

    Sieglinde Zelzer

    2015-05-01

    Full Text Available Metabolic dysfunctions might play a crucial role in the pathophysiology of thyroid dysfunctions. This study aimed to investigate the impact of a controlled diet (normal versus high fat feeding on hypothyroid and hyperthyroid Sprague Dawley rats. Female Sprague Dawley rats (n = 66 were grouped into normal diet (n = 30 and high-fat diet (n = 36 groups and subdivided into controls, hypothyroid and hyperthyroid groups, induced through propylthiouracil or triiodothyronine (T3 treatment, respectively. After 12 weeks of treatment metabolic parameters, such as oxidized LDL (oxLDL, malondialdehyde (MDA, 4-hydroxynonenal (HNE, the lipid profile, body weight and food intake parameters were analyzed. Successfully induced thyroid dysfunctions were shown by T3 levels, both under normal and high fat diet. Thyroid dysfunctions were accompanied by changes in calorie intake and body weight as well as in the lipid profile. In detail, hypothyroid rats showed significantly decreased oxLDL levels, whereas hyperthyroid rats showed significantly increased oxLDL levels. These effects were seen under high fat diet and were less pronounced with normal feeding. Taken together, we showed for the first time in female SD rats that only hyper-, but not hypothyroidism, is associated with high atherogenic oxidized LDL irrespective of normal or high-fat diet in Sprague Dawley rats.

  12. Immediate effect of instrumentation on the subgingival microflora in deep inflamed pockets under strict plaque control

    NARCIS (Netherlands)

    Rhemrev, GE; Timmerman, MF; Veldkamp, A; Van Winkelhoff, AJ; Van der Velden, U

    Objective: To investigate (1) reduction in the number of microorganisms obtained directly after subgingival instrumentation, (2) rate of bacterial re-colonization during 2 weeks, under supragingival plaque-free conditions. Materials and Method: Effects of subgingival instrumentation were measured at

  13. A strict experimental test of macroscopic realism in a superconducting flux qubit.

    Science.gov (United States)

    Knee, George C; Kakuyanagi, Kosuke; Yeh, Mao-Chuang; Matsuzaki, Yuichiro; Toida, Hiraku; Yamaguchi, Hiroshi; Saito, Shiro; Leggett, Anthony J; Munro, William J

    2016-11-04

    Macroscopic realism is the name for a class of modifications to quantum theory that allow macroscopic objects to be described in a measurement-independent manner, while largely preserving a fully quantum mechanical description of the microscopic world. Objective collapse theories are examples which aim to solve the quantum measurement problem through modified dynamical laws. Whether such theories describe nature, however, is not known. Here we describe and implement an experimental protocol capable of constraining theories of this class, that is more noise tolerant and conceptually transparent than the original Leggett-Garg test. We implement the protocol in a superconducting flux qubit, and rule out (by ∼84 s.d.) those theories which would deny coherent superpositions of 170 nA currents over a ∼10 ns timescale. Further, we address the 'clumsiness loophole' by determining classical disturbance with control experiments. Our results constitute strong evidence for the superposition of states of nontrivial macroscopic distinctness.

  14. Photoluminescence investigation of strictly ordered Ge dots grown on pit-patterned Si substrates

    International Nuclear Information System (INIS)

    Brehm, Moritz; Grydlik, Martyna; Tayagaki, Takeshi; Schmidt, Oliver G; Langer, Gregor; Schäffler, Friedrich

    2015-01-01

    We investigate the optical properties of ordered Ge quantum dots (QDs) by means of micro-photoluminescence spectroscopy (PL). These were grown on pit-patterned Si(001) substrates with a wide range of pit-periods and thus inter QD-distances (425–3400 nm). By exploiting almost arbitrary inter-QD distances achievable in this way we are able to choose the number of QDs that contribute to the PL emission in a range between 70 and less than three QDs. This well-defined system allows us to clarify, by PL-investigation, several points which are important for the understanding of the formation and optical properties of ordered QDs. We directly trace and quantify the amount of Ge transferred from the surrounding wetting layer (WL) to the QDs in the pits. Moreover, by exploiting different pit-shapes, we reveal the role of strain-induced activation energy barriers that have to be overcome for charge carriers generated outside the dots. These need to diffuse between the energy minimum of the WL in and between the pits, and the one in the QDs. In addition, we demonstrate that the WL in the pits is already severely intermixed with Si before upright QDs nucleate, which further enhances intermixing of ordered QDs as compared to QDs grown on planar substrates. Furthermore, we quantitatively determine the amount of Ge transferred by surface diffusion through the border region between planar and patterned substrate. This is important for the growth of ordered islands on patterned fields of finite size. We highlight that the Ge WL-facets in the pits act as PL emission centres, similar to upright QDs. (paper)

  15. In vitro effect of intracanal medicaments on strict anaerobes by means of the broth dilution method

    Directory of Open Access Journals (Sweden)

    ROSA Odila Pereira da Silva

    2002-01-01

    Full Text Available The determination of bacterial susceptibility to intracanal medicaments is a necessity. Nevertheless, few studies utilize the proper methodology to carry out that evaluation with anaerobes. In this study, the steps of a broth dilution method, carried out in microplates (microdilution and tubes (macrodilution, to test the effect of traditional intracanal medicaments on anaerobic bacteria are described. The results are presented as values of minimal inhibitory and bactericidal concentrations (MIC and MBC. Standardized inocula of the anaerobic bacteria Prevotella nigrescens (ATCC 33563, Fusobacterium nucleatum (ATCC 25586 and Clostridium perfringens (ATCC 13124, in reinforced Clostridium medium (RCM and supplemented Brucella broth, were submitted to different concentrations of calcium hydroxide, chlorhexidine digluconate, camphorated paramonochlorophenol and formocresol solutions. The drugs were diluted in the same culture broths, in microplates and tubes, and were then incubated in anaerobiosis jars at 37ºC for 48 or 96 hours. The determination of MICs was carried out through visual and spectrophotometric readings, and the determination of MBCs, through the plating of aliquots on RCM-blood agar. For that kind of study, the macromethod with spectrophotometric reading should be the natural choice. MICs and MBCs obtained with the macromethod were compatible with the known clinical performance of the studied medications, and the values varied according to the bacteria and culture media employed. RCM was the most effective medium and C. perfringens, the most resistant microorganism.

  16. Agricultural freight : network access and issues.

    Science.gov (United States)

    2010-04-01

    Objectives: Better understand inherent risk of highly : contagious disease spread among : Vermont dairy farms; Better prepare response agencies and : individuals; Stimulate continuity of business planning : among producers and allied industry

  17. Smart homes design, implementation and issues

    CERN Document Server

    Suryadevara, Nagender Kumar

    2015-01-01

    The book addresses issues towards the design and development of Wireless Sensor Network based Smart Home and fusion of Real-Time Data for Wellness Determination of an elderly person living alone in a Smart Home. The fundamentals of selection of sensor, fusion of sensor data, system design, modelling, characterizations, experimental investigations and analyses have been covered. This book will be extremely useful for the engineers and researchers especially higher undergraduate, postgraduate students as well as practitioners working on the development of Wireless Sensor Networks, Internet of Things and Data Mining.

  18. Current sociological theories and issues in tourism

    OpenAIRE

    Cohen, E; Cohen, SA

    2012-01-01

    This article reviews the changing nature of contemporary tourism and sociological approaches to its study. We examine the broad social trends and specific historical events that recently affected tourism and discuss how the focus of sociological inquiry in tourism studies shifted from earlier discourses of authenticity and the tourist gaze to three novel theoretical approaches, the mobilities “paradigm”, the performativity approach and actor-network theory (ANT), which each reflect a broader ...

  19. Becoming more sustainable: concepts and issues

    Energy Technology Data Exchange (ETDEWEB)

    Pirages, D.C. [Maryland Univ., Dep. of Government and Politics, Harrison Program on the Future Global Agenda, College Park, MD (United States)

    1996-11-01

    The automobile and associated mobility system have had a major economic and ecological impact on human societies. The industrial revolution, during which the internal combustion engine has played a major role, has shaped secular, materialistic societies and associated consumption patterns that cannot be sustained in a future world of eight billion people. Creating a more sustainable world means maximizing human satisfaction while minimizing human impact on nature. Becoming more sustainable is best envisioned as a continuing process in which constraints and possibilities change over time and space. The sustainable process raises major controversies including how to define and measure progress, how to apportion wealth among generations, and between free trade and environmental preservation. Sustainable mobility implies major changes in approaches to transportation including stressing psychological rather than physical mobility, designing speciality vehicles for emerging niches, and placing special emphasis on mass transit systems for emerging megacities. (author) 17 refs.

  20. E-Government: Initiatives, Developments, and Issues.

    Science.gov (United States)

    Aldrich, Duncan; Bertot, John Carlo; McClure, Charles R.

    2002-01-01

    Provides a background of government efforts to incorporate telecommunication and computer technologies to improve government performance and enhance citizen access to government information and services. Describes this symposium issue which discusses key issues that affect the success and implementation of electronic government initiatives. (LRW)

  1. Environmental Adult Education. Trends and Issues Alerts.

    Science.gov (United States)

    Imel, Susan

    Environmentalism has become a part of the culture, and environmentalists now constitute a major social movement. The solutions to many current environmental problems require a local or national response, but solutions to other problems will require a global response. Major United Nations reports have recognized that solving global environmental…

  2. National Security Education Program: Background and Issues

    Science.gov (United States)

    2005-01-21

    Education Board of designees of the Secretaries of Education and State , among others. However, there is no statutory provision for analogous...administered by the Departments of Education and State , they argue, those other programs have broader purposes than the NSEP. The statement of purpose in the

  3. Natural gas hydrate occurrence and issues

    Science.gov (United States)

    Kvenvolden, K.A.

    1994-01-01

    Naturally occurring gas hydrate is found in sediment of two regions: (1) continental, including continental shelves, at high latitudes where surface temperatures are very cold, and (2) submarine outer continental margins where pressures are very high and bottom-water temperatures are near 0??C. Continental gas hydrate is found in association with onshore and offshore permafrost. Submarine gas hydrate is found in sediment of continental slopes and rises. The amount of methane present in gas hydrate is thought to be very large, but the estimates that have been made are more speculative than real. Nevertheless, at the present time there has been a convergence of ideas regarding the amount of methane in gas hydrate deposits worldwide at about 2 x 1016 m3 or 7 x 1017 ft3 = 7 x 105 Tcf [Tcf = trillion (1012) ft3]. The potentially large amount of methane in gas hydrate and the shallow depth of gas hydrate deposits are two of the principal factors driving research concerning this substance. Such a large amount of methane, if it could be commercially produced, provides a potential energy resource for the future. Because gas hydrate is metastable, changes of surface pressure and temperature affect its stability. Destabilized gas hydrate beneath the sea floor leads to geologic hazards such as submarine mass movements. Examples of submarine slope failures attributed to gas hydrate are found worldwide. The metastability of gas hydrate may also have an effect on climate. The release of methane, a 'greenhouse' gas, from destabilized gas hydrate may contribute to global warming and be a factor in global climate change.

  4. The Culture War and Issue Salience

    DEFF Research Database (Denmark)

    Wroe, Andrew; Ashbee, Edward; Gosling, Amanda

    2014-01-01

    Despite much talk of a culture war, scholars continue to argue over whether the American public is divided on cultural and social issues. Some of the most prominent work in this area, such as Fiorina's Culture War?, has rejected the idea. However, this work has in turn been criticized for focussi...... culture. Both findings enhance but also complicate our theoretical understanding of the culture war, and have important real-world consequences for American politics.......Despite much talk of a culture war, scholars continue to argue over whether the American public is divided on cultural and social issues. Some of the most prominent work in this area, such as Fiorina's Culture War?, has rejected the idea. However, this work has in turn been criticized for focussing...... only on the distribution of attitudes within the American public and ignoring the possibility that the culture war may also be driven by the increasing strength with which sections of the population hold their opinions. This paper tests the strength, or saliency, hypothesis using individual-level over...

  5. Medical records and issues in negligence

    Directory of Open Access Journals (Sweden)

    Joseph Thomas

    2009-01-01

    Full Text Available It is very important for the treating doctor to properly document the management of a patient under his care. Medical record keeping has evolved into a science of itself. This will be the only way for the doctor to prove that the treatment was carried out properly. Moreover, it will also be of immense help in the scientific evaluation and review of patient management issues. Medical records form an important part of the management of a patient. It is important for the doctors and medical establishments to properly maintain the records of patients for two important reasons. The first one is that it will help them in the scientific evaluation of their patient profile, helping in analyzing the treatment results, and to plan treatment protocols. It also helps in planning governmental strategies for future medical care. But of equal importance in the present setting is in the issue of alleged medical negligence. The legal system relies mainly on documentary evidence in a situation where medical negligence is alleged by the patient or the relatives. In an accusation of negligence, this is very often the most important evidence deciding on the sentencing or acquittal of the doctor. With the increasing use of medical insurance for treatment, the insurance companies also require proper record keeping to prove the patient′s demand for medical expenses. Improper record keeping can result in declining medical claims. It is disheartening to note that inspite of knowing the importance of proper record keeping it is still in a nascent stage in India. It is wise to remember that "Poor records mean poor defense, no records mean no defense". Medical records include a variety of documentation of patient′s history, clinical findings, diagnostic test results, preoperative care, operation notes, post operative care, and daily notes of a patient′s progress and medications. A properly obtained consent will go a long way in proving that the procedures were conducted with the concurrence of the patient. A properly written operative note can protect a surgeon in case of alleged negligence due to operative complications. It is important that the prescription for drugs should be legible with the name of the patient, date, and the signature of the doctor. An undated prescription can land a doctor in trouble if the patient misuses it. There are also many records that are indirectly related to patient management such as accounts records, service records of the staff, and administrative records, which are also useful as evidences for litigation purposes. Medical recording needs the concerted effort of a number of people involved in patient care. The doctor is the prime person who has to oversee this process and is primarily responsible for history, physical examination, treatment plans, operative records, consent forms, medications used, referral papers, discharge records, and medical certificates. There should be proper recording of nursing care, laboratory data, reports of diagnostic evaluations, pharmacy records, and billing processes. This means that the paramedical and nursing staff also should be trained in proper maintenance of patient records. The medical scene in India extends from smaller clinics to large hospitals. Medical record keeping is a specialized area in bigger teaching and corporate hospitals with separate medical records officers handling these issues. However, it is yet to develop into a proper process in the large number of smaller clinics and hospitals that cater to a large section of the people in India.

  6. Carbon Pricing: Design, Experiences and Issues

    DEFF Research Database (Denmark)

    Carbon Pricing reflects upon and further develops the ongoing and worthwhile global debate into how to design carbon pricing, and how to utilize the financial proceeds in the best possible way for society. The world has recently witnessed a significant downward adjustment in fossil fuel prices......, which has negative implications for the future of our environment. In light of these negative developments, it is important to understand the benefits of environmental sustainability through well-documented research. This discerning book considers the design of carbon taxes and examines...

  7. Forms and Issues in Experiential Learning

    Science.gov (United States)

    Moore, David Thornton

    2010-01-01

    Programs falling under the general rubric of "experiential education" take a number of forms, varying on several dimensions; what is offered here is a schematic overview. In general, they all involve students in activities that look rather different from more traditional classroom-based methods: (1) the formal lecture and discussion; (2) the…

  8. Career Education Models. Trends and Issues Alert.

    Science.gov (United States)

    Brown, Bettina Lankard

    The evolution of the workplace has required changes in the guidance and counseling practices of career education (CE). Basic elements of CE strategies for enhancing students' career awareness, exploration, and planning are still in place, but contemporary issues such as life-work balance, involuntary career transitions, and mentoring have led to…

  9. Technology of disaster response robot and issues

    International Nuclear Information System (INIS)

    Tadokoro, Satoshi

    2013-01-01

    The needs, function structure , ability of disaster response robot are stated. Robots are classified by move mode such as Unmanned Ground Vehicle (UGV), Legged Robots, Exoskeleton, Unmanned Aerial Vehicle (UAV), Wall Climbing Robots, robots for narrow space. Quince, disaster response robot, collected at first information in the building of Fukushima Daiichi Nuclear Power Station. Functions of rescue robots and technical problems under disaster conditions, shape and characteristics of robots and TRL, PackBot, Pelican, Quince, scope camera, and three-dimensional map made by Quince are illustrated. (S.Y.)

  10. Digital telephony analysis model and issues

    Science.gov (United States)

    Keuthan, Lynn M.

    1995-09-01

    Experts in the fields of digital telephony and communications security have stated the need for an analytical tool for evaluating complex issues. Some important policy issues discussed by experts recently include implementing digital wire-taps, implementation of the 'Clipper Chip', required registration of encryption/decryption keys, and export control of cryptographic equipment. Associated with the implementation of these policies are direct costs resulting from implementation, indirect cost benefits from implementation, and indirect costs resulting from the risks of implementation or factors reducing cost benefits. Presented herein is a model for analyzing digital telephony policies and systems and their associated direct costs and indirect benefit and risk factors. In order to present the structure of the model, issues of national importance and business-related issues are discussed. The various factors impacting the implementation of the associated communications systems and communications security are summarized, and various implementation tradeoffs are compared based on economic benefits/impact. The importance of the issues addressed herein, as well as other digital telephony issues, has greatly increased with the enormous increases in communication system connectivity due to the advance of the National Information Infrastructure.

  11. National Security Education Program: Background and Issues

    National Research Council Canada - National Science Library

    Kuenzi, Jeffrey J; Riddle, Wayne C

    2005-01-01

    ... (NSEA, Title VIII of P.L. 102-183), provides aid for international education and foreign language studies by American undergraduate and graduate students, plus grants to institutions of higher education...

  12. The Corporate Library and Issues Management.

    Science.gov (United States)

    Lancaster, F. W.; Loescher, Jane

    1994-01-01

    Discussion of corporate library services and the role of the librarian focuses on the recognition and tracking of issues of potential significance to the corporation, or issues management. Topics addressed include environmental scanning of relevant literature, and the use of databases to track issues. (16 references) (LRW)

  13. MILSTRIP. MILitary, STandard, Requisitioning and Issue Procedures.

    Science.gov (United States)

    1987-05-01

    DTA Asset Support Request submitted for obsolete/inactive NSN which cannot be supported. (Applies to reference (cc) DZG trans- action rejects only...Republic of CV Cayman Islands CJ Chad CD Chile CI China (People’s Republic of) CH Colombia CO Colombia (International Narcotics Control) D5 Comoros CR...Liechtenstein LS Lithuania LH Luxembourg LX Macau MC Madagascar MA Malawi MI Malaysia MF Maldives MV Mali RM Malta MT Martinique MB Mauritania MR Mauritius

  14. The ingestion pathway comments and issues

    International Nuclear Information System (INIS)

    McDonnell, Lawrence J.

    1989-01-01

    Full text: The Ingestion Pathway and its recent emphasis on planning for nuclear power plant emergencies has created activity at all levels of government. Federal Emergency Management Agency (FEMA) guidelines have been developed and there has been an urgency placed on implementing these guides and planning standards at all levels of government. This global approach has led to confusion and in some cases rapid development of public brochures at the state level. These brochures are meant to educate the public in the need for protective action in the ingestion pathway. Some forethought on the planning process and the integration of the protective action guidelines seems in order. Some issues that should be addressed are listed below: Suggested consideration of issues to facilitate the planning process: - Review existing technical specifications of nuclear power plants requiring environmental monitoring. This should provide at least the baseline sampling of food products for site specific plants; - Review state monitoring/analysis of sampling programs and NRC contracts to states for radiological monitoring of nuclear power facilities; - Encourage each state to involve food producers at an early date in the planning development. Such producer associations as the Daily Associations, Marketing Boards, and Cooperatives are valuable resources in implementing plans because they represent the affected economic impacted parties; - Involve and educate the agricultural extension agencies in the planning process so they can inform the public through their usual points of contact; - Set up principle agency responsibilities in existing state specific framework. For example, the farm or food producers normally are familiar with their extension agents. Use this relationship to help the affected producers understand the protective actions that will be implemented in case of severe nuclear power plant accidents; - Recognize that the disaster services agencies are lead agencies for implementing evacuation procedures but may have no experience in relating to food production or farming practices in the area. Agriculture extension agents and their communication networks may be the primary notification and implementation method used in protecting the food pathways; - Integrate planning activities so that conflicts and confusion can be avoided. For instance, the requirements for monitoring the population in the EPZ require that 20% of the evacuated population require monitoring for contamination at reception centers located about 15 miles from the plant. Existing Food and Drug Administration (FDA) guides for protection of dairy products to 50 miles would indicate contamination of microcurie amounts of iodine and cesium at a reception center located 15 miles from the plant. This dilemma has been ignored in the planning process and makes one question the approach of the issuance of stand alone guides by the federal agencies; - Emergency workers should be considered the same as the general public. If samples are gathered by emergency workers at locations (50-100 miles) from the affected area, it does not seem sensible to imply by protective dress that the population in those areas may be contaminated. The protective measures for these workers should be comparable to the risk that is involved; - Standard Procedures and Analysis: One of the most difficult problems in assessing the radiological impacts for real events such as Three Mile Island has been interpreting the data. Often, the data is either incorrect or the errors are unknown. This leads to difficulty in taking correct protective action and loss of confidence in the entire emergency response system; - The total emergency response program must include the federal resources at the outset. It is unreasonable to assume that the state should duplicate the federal resources in meeting the federal guidelines. (author)

  15. Zakat Institution in Malaysia: Problems and Issues

    Directory of Open Access Journals (Sweden)

    Azman Ab Rahman

    2012-06-01

    Full Text Available Zakat administration in Malaysia is a State matter in particular relating to the passing of regulations and statutes. The respective Heads of States (the rulers are heads of Islam as enshrined in the Federal Constitution. This paper gives a chronicle of the transformation and phases of development of zakat institution in Malaysia. Zakat institution can play an important role in complementing the Government’s poverty eradication effort although its scope is for the poor and needy Muslims only. Besides the poorand needy, there are other beneficiaries allowed by the Syariah. Its success would also help to buffer the effects of recession of the economy on the poor through capacity building and mindsettransformation. The effectiveness of the zakat institution in carrying out its duties would depend on a number of factors viz. expansionof new resources for zakat, the collection of zakat from tangible and intangible properties, systematic zakat management, efficientzakat distribution and the thoroughness of implementation of Islamic rules. The article would discuss on matters that should be dealtwith in order to improve zakat institutions in Malaysia in terms of the inefficiency issue, prospective payers, and capacity building.

  16. Medical records and issues in negligence.

    Science.gov (United States)

    Thomas, Joseph

    2009-07-01

    It is very important for the treating doctor to properly document the management of a patient under his care. Medical record keeping has evolved into a science of itself. This will be the only way for the doctor to prove that the treatment was carried out properly. Moreover, it will also be of immense help in the scientific evaluation and review of patient management issues. Medical records form an important part of the management of a patient. It is important for the doctors and medical establishments to properly maintain the records of patients for two important reasons. The first one is that it will help them in the scientific evaluation of their patient profile, helping in analyzing the treatment results, and to plan treatment protocols. It also helps in planning governmental strategies for future medical care. But of equal importance in the present setting is in the issue of alleged medical negligence. The legal system relies mainly on documentary evidence in a situation where medical negligence is alleged by the patient or the relatives. In an accusation of negligence, this is very often the most important evidence deciding on the sentencing or acquittal of the doctor. With the increasing use of medical insurance for treatment, the insurance companies also require proper record keeping to prove the patient's demand for medical expenses. Improper record keeping can result in declining medical claims. It is disheartening to note that inspite of knowing the importance of proper record keeping it is still in a nascent stage in India. It is wise to remember that "Poor records mean poor defense, no records mean no defense". Medical records include a variety of documentation of patient's history, clinical findings, diagnostic test results, preoperative care, operation notes, post operative care, and daily notes of a patient's progress and medications. A properly obtained consent will go a long way in proving that the procedures were conducted with the concurrence of the patient. A properly written operative note can protect a surgeon in case of alleged negligence due to operative complications. It is important that the prescription for drugs should be legible with the name of the patient, date, and the signature of the doctor. An undated prescription can land a doctor in trouble if the patient misuses it. There are also many records that are indirectly related to patient management such as accounts records, service records of the staff, and administrative records, which are also useful as evidences for litigation purposes. Medical recording needs the concerted effort of a number of people involved in patient care. The doctor is the prime person who has to oversee this process and is primarily responsible for history, physical examination, treatment plans, operative records, consent forms, medications used, referral papers, discharge records, and medical certificates. There should be proper recording of nursing care, laboratory data, reports of diagnostic evaluations, pharmacy records, and billing processes. This means that the paramedical and nursing staff also should be trained in proper maintenance of patient records. The medical scene in India extends from smaller clinics to large hospitals. Medical record keeping is a specialized area in bigger teaching and corporate hospitals with separate medical records officers handling these issues. However, it is yet to develop into a proper process in the large number of smaller clinics and hospitals that cater to a large section of the people in India.

  17. Tacit Knowledge. Trends and Issues Alert.

    Science.gov (United States)

    Imel, Susan

    Tacit knowledge, the knowledge that workers possess but do not articulate, is associated with terms such as "skill,""know-how,""working knowledge," and "expertise" that are used to describe knowledge about and ability to perform work. Learning that takes place through apprenticeships draws heavily on tacit…

  18. Interpersonal communication and issues for autonomous vehicles.

    Science.gov (United States)

    2017-06-01

    Interpersonal roadway communication is a vital component of the transportation system. Road users communicate to coordinate movement and increase roadway safety. Future autonomous vehicle research needs to account for the role of interpersonal roadwa...

  19. Measuring Youth Joblessness: Concepts, Tools, and Issues.

    Science.gov (United States)

    Passmore, David Lynn

    1981-01-01

    Discusses the procedures for collecting unemployment statistics. Criticisms of and alternatives to this method are explored. The youth unemployment rate is discussed in relation to these problems and to the goals of vocational and technical education. (CT)

  20. Community Asset Mapping. Trends and Issues Alert.

    Science.gov (United States)

    Kerka, Sandra

    Asset mapping involves documenting tangible and intangible resources of a community viewed as a place with assets to be preserved and enhanced, not deficits to be remedied. Kretzmann and McKnight (1993) are credited with developing the concept of asset-based community development (ABCD) that draws on appreciative inquiry; recognition of social…

  1. Trends and issues in international development cooperation

    Directory of Open Access Journals (Sweden)

    Gilles Carbonnier

    2010-03-01

    Full Text Available Aid volume from OECD countries has set a new record. However, the assistance recorded as ODA includes categories that do not contribute to reducing poverty in developing countries. Emerging economies and private donors provide an increasing proportion of aid. Progress has been made in implementing the 2005 Paris Declaration on Aid Effectiveness in a few fields, such as untying aid, but the results do not meet expectations. The approach, too often purely technical, omits taking fully into consideration the political dimension which strongly affects aid effectiveness. The issue of overall policy coherence receives renewed attention at a time when the debate about climate change is leading development agencies to reconsider goals and strategies.

  2. Venous access: options, approaches and issues

    Energy Technology Data Exchange (ETDEWEB)

    Asch, M.R. [Univ. of Toronto, Mount Sinai Hospital, Dept. of Medical Imaging, Toronto, Ontario (Canada)

    2001-06-01

    Venous access is an essential part of medical practice. It is needed to obtain blood samples to make the diagnosis and to administer fluids or medicines as part of treatment. Although relatively new in the history of medicine, the placement and maintenance of the various venous access devices now occupies a significant portion of many vascular and interventional radiology practices. Thus, it is important to have a thorough understanding of these devices and their uses. The first long-term venous access devices were used in 1973. These were placed via a surgical cut-down on the subclavian vein. In 1982, the first subcutaneous implantable ports were described. These procedures were initially performed by surgeons, but over the last 5-10 years, both the insertion and management of these devices has shifted to interventional radiologists. Peripherally inserted central catheter (PICC) lines have almost completely supplanted the use of standard central lines (Fig. 1). A number of factors have facilitated this - namely, ready and less expensive room access, outpatient procedure and radiologists' accessibility and familiarity with image-guidance procedures and catheters and guide wires. (author)

  3. Venous access: options, approaches and issues

    International Nuclear Information System (INIS)

    Asch, M.R.

    2001-01-01

    Venous access is an essential part of medical practice. It is needed to obtain blood samples to make the diagnosis and to administer fluids or medicines as part of treatment. Although relatively new in the history of medicine, the placement and maintenance of the various venous access devices now occupies a significant portion of many vascular and interventional radiology practices. Thus, it is important to have a thorough understanding of these devices and their uses. The first long-term venous access devices were used in 1973. These were placed via a surgical cut-down on the subclavian vein. In 1982, the first subcutaneous implantable ports were described. These procedures were initially performed by surgeons, but over the last 5-10 years, both the insertion and management of these devices has shifted to interventional radiologists. Peripherally inserted central catheter (PICC) lines have almost completely supplanted the use of standard central lines (Fig. 1). A number of factors have facilitated this - namely, ready and less expensive room access, outpatient procedure and radiologists' accessibility and familiarity with image-guidance procedures and catheters and guide wires. (author)

  4. Cotton : Market setting, trade policies, and issues

    OpenAIRE

    Baffes, John

    2004-01-01

    The value of world cotton production in 2000-01 has been estimated at about $20 billion, down from $35 billion in 1996-97 when cotton prices were 50 percent higher. Although cotton's share in world merchandise trade is insignificant (about 0.12 percent), it is very important to a number of developing countries. Cotton accounts for approximately 40 percent of total merchandise export earnin...

  5. How Congruent Is a Strict Uniform Policy with Enhanced Academic Achievement and Self-Beliefs in Early Adolescence?

    Science.gov (United States)

    Hoskins, Jo A.

    2014-01-01

    This study focuses on the analysis of the impact of school uniforms on student self-esteem and self-efficacy. In the past, schools have implemented school uniform policies in order to help improve student achievement as well as strengthen discipline. However, previous research has indicated an association, which is tenuous at best, with regard to…

  6. Second harmonic generation in gallium phosphide microdisks on silicon: from strict \\bar{4} to random quasi-phase matching

    Science.gov (United States)

    Guillemé, P.; Dumeige, Y.; Stodolna, J.; Vallet, M.; Rohel, T.; Létoublon, A.; Cornet, C.; Ponchet, A.; Durand, O.; Léger, Y.

    2017-06-01

    The convergence of nonlinear optical devices and silicon photonics is a key milestone for the practical development of photonic integrated circuits. The associated technological issues often stem from material incompatibility. This is the case of second order nonlinear processes in monolithically integrated III-V semiconductor devices on silicon, where structural defects called antiphase domains strongly impact the optical properties of the material. We theoretically investigate the influence of antiphase domains on second harmonic generation in III-V whispering gallery mode microresonators on silicon and focus on the effects of the antiphase domains’ mean size (i.e. the correlation length of the distribution). We demonstrate that the domain distributions can have opposite effects depending on the nonlinear process under consideration: while antiphase domains negatively impact second harmonic generation under \\bar{4} quasi-phase matching conditions (independent of the correlation length), large conversion efficiencies can arise far from \\bar{4}-quasi-phase matching provided that the APD correlation length remains within an appropriate range, and is still compatible with the spontaneous emergence of such defects in the usual III-V on Si epilayers. Such a build-up can be explained by the occurrence of random quasi-phase matching in the system.

  7. Peculiarities of one-carbon metabolism in the strict carnivorous cat and the role in feline hepatic lipidosis.

    Science.gov (United States)

    Verbrugghe, Adronie; Bakovic, Marica

    2013-07-19

    Research in various species has indicated that diets deficient in labile methyl groups (methionine, choline, betaine, folate) produce fatty liver and links to steatosis and metabolic syndrome, but also provides evidence of the importance of labile methyl group balance to maintain normal liver function. Cats, being obligate carnivores, rely on nutrients in animal tissues and have, due to evolutionary pressure, developed several physiological and metabolic adaptations, including a number of peculiarities in protein and fat metabolism. This has led to specific and unique nutritional requirements. Adult cats require more dietary protein than omnivorous species, maintain a consistently high rate of protein oxidation and gluconeogenesis and are unable to adapt to reduced protein intake. Furthermore, cats have a higher requirement for essential amino acids and essential fatty acids. Hastened use coupled with an inability to conserve certain amino acids, including methionine, cysteine, taurine and arginine, necessitates a higher dietary intake for cats compared to most other species. Cats also seemingly require higher amounts of several B-vitamins compared to other species and are predisposed to depletion during prolonged inappetance. This carnivorous uniqueness makes cats more susceptible to hepatic lipidosis.

  8. Minimal L-infinity-type spaces on strictly pseudoconvex domains on which the Bergman projection is continuous

    Czech Academy of Sciences Publication Activity Database

    Engliš, Miroslav; Hänninen, T.; Taskinen, J.

    2006-01-01

    Roč. 32, č. 2 (2006), s. 253-275 ISSN 0362-1588 R&D Projects: GA ČR(CZ) GA201/03/0041; GA AV ČR(CZ) IAA1019304 Institutional research plan: CEZ:AV0Z10190503 Keywords : Bergman projection * weighted supremum norms * locally convex space Subject RIV: BA - General Mathematics Impact factor: 0.354, year: 2006

  9. Strictly by the Book: Textbooks and the Control of Production in the North American Pulp and Paper Industry.

    Science.gov (United States)

    Hull, James P.

    1998-01-01

    Uses the textbook, "The Manufacture of Pulp and Paper," as a case study of technical education in a process industry during the post-World War I period. Illustrates how codification of knowledge about industrial processes served the hegemony of university-trained scientists, the leaders and beneficiaries of this new period of industrial…

  10. Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)

    DEFF Research Database (Denmark)

    Verbrugghe, A; Hesta, M; Daminet, S

    2012-01-01

    In six normal-weight and six obese cats, the metabolic effect of propionate absorbed from the colon was assessed. Two colonic infusions were tested in a crossover design with intervals of 4 weeks. The test solution contained 4 mmol sodium propionate per kg ideal body weight in a 0.2% NaCl solution...

  11. MORA DEBITORIS AND THE PRINCIPLE OF STRICT LIABILITY: SCOIN TRADING (PTY LTD V BERNSTEIN 2011 2 SA 118 (SCA

    Directory of Open Access Journals (Sweden)

    SJ Cornelius

    2012-12-01

    Full Text Available Parties generally enter into contractual relations with the sincere intention to fulfil all the obligations created in terms of their contract. However, for various reasons, parties sometimes do not comply with the terms of their contract. Where a party fails to perform at the agreed date and time or after receiving a demand from the creditor, the debtor commits breach of contract in the form of mora debitoris. The question then arises whether or not a debtor would also commit breach in the form of mora debitoris if the delay in performance cannot be attributed to wilful disregard of the contract or a negligent failure to perform on time. This was the question which the court had to determine in Scoin Trading (Pty Ltd v Bernstein.

  12. Absence of strictly age-related resistance to Mycoplasma hyosynoviae infection in 6-week-old pigs

    DEFF Research Database (Denmark)

    Lauritsen, Klara Tølbøll; Hagedorn-Olsen, Tine; Filskov Friis, Niels

    2008-01-01

    intranasally with the agent and autopsied at day 11 or 13 after infection. One uninoculated pig per age group was included as a negative control. Just as the 13-week-old pigs, the 6-week-old piglets were susceptible to blood, joint and tonsillar infection with M. hyosynoviae and developed clinical arthritis...

  13. Impacts of Community Forest Management and Strictly Protected Areas on Deforestation and Human Well-Being in Madagascar

    DEFF Research Database (Denmark)

    Rasolofoson, Ranaivo Andriarilala

    , conditional on household proximity to forest and education level. In conclusion, the impacts of CFM vary with household characteristics: some may lose while others may gain. iii) The potential of the Global Person Generated Index (GPGI) for evaluating the perceived impact of conservation interventions......, these large scale studies may be of limited use for project managers who want to build locally legitimate interventions or those who want a deeper understanding of how conservation interventions affect local people. In the third manuscript, we used a subjective measure of well-being (the GPGI) in combination...... with participatory approach to establish cause-effect relationship between interventions and locally meaningful outcomes. This has limited value for quantitatively measuring the magnitude of impacts; but holds some promises for project managers who seek local participation and social sustainability. Conservation has...

  14. Fermentation of animal components in strict carnivores: A comparative study with cheetah fecal inoculum 1,2

    NARCIS (Netherlands)

    Depauw, S.; Bosch, Guido; Hesta, M.; Whitehouse-Tedd, K.; Hendriks, W.H.; Kaandorp, J.; Janssens, P.J.

    2012-01-01

    The natural diet of felids contains highly digestible animal tissues but also fractions resistant to small intestinal digestion, which enter the large intestine where they may be fermented by the resident microbial population. Little information exists on the microbial degradability of animal

  15. Functional Itô versus Banach space stochastic calculus and strict solutions of semilinear path-dependent equations

    Science.gov (United States)

    Cosso, Andrea; Russo, Francesco

    2016-11-01

    Functional Itô calculus was introduced in order to expand a functional F(t,Xṡ+t,Xt) depending on time t, past and present values of the process X. Another possibility to expand F(t,Xṡ+t,Xt) consists in considering the path Xṡ+t = {Xx+t,x ∈ [-T, 0]} as an element of the Banach space of continuous functions on C([-T, 0]) and to use Banach space stochastic calculus. The aim of this paper is threefold. (1) To reformulate functional Itô calculus, separating time and past, making use of the regularization procedures which match more naturally the notion of horizontal derivative which is one of the tools of that calculus. (2) To exploit this reformulation in order to discuss the (not obvious) relation between the functional and the Banach space approaches. (3) To study existence and uniqueness of smooth solutions to path-dependent partial differential equations which naturally arise in the study of functional Itô calculus. More precisely, we study a path-dependent equation of Kolmogorov type which is related to the window process of the solution to an Itô stochastic differential equation with path-dependent coefficients. We also study a semilinear version of that equation.

  16. Peculiarities of One-Carbon Metabolism in the Strict Carnivorous Cat and the Role in Feline Hepatic Lipidosis

    Directory of Open Access Journals (Sweden)

    Marica Bakovic

    2013-07-01

    Full Text Available Research in various species has indicated that diets deficient in labile methyl groups (methionine, choline, betaine, folate produce fatty liver and links to steatosis and metabolic syndrome, but also provides evidence of the importance of labile methyl group balance to maintain normal liver function. Cats, being obligate carnivores, rely on nutrients in animal tissues and have, due to evolutionary pressure, developed several physiological and metabolic adaptations, including a number of peculiarities in protein and fat metabolism. This has led to specific and unique nutritional requirements. Adult cats require more dietary protein than omnivorous species, maintain a consistently high rate of protein oxidation and gluconeogenesis and are unable to adapt to reduced protein intake. Furthermore, cats have a higher requirement for essential amino acids and essential fatty acids. Hastened use coupled with an inability to conserve certain amino acids, including methionine, cysteine, taurine and arginine, necessitates a higher dietary intake for cats compared to most other species. Cats also seemingly require higher amounts of several B-vitamins compared to other species and are predisposed to depletion during prolonged inappetance. This carnivorous uniqueness makes cats more susceptible to hepatic lipidosis.

  17. "Strictly in the Capacity of Servant": The Interconnection between Residential and School Segregation in Oxnard, California, 1934-1954

    Science.gov (United States)

    Garcia, David G.; Yosso, Tara J.

    2013-01-01

    To introduce their examination of the social production of segregated space and power relations in Oxnard, California from 1934 to 1954, the authors utilize portions of a letter written by Alice Shaffer, April 21, 1938, to the Oxnard School Board of Trustees. Shaffer outlines the seemingly shared concerns of her neighbors about a disruption of the…

  18. Classroom Management Strategies of Highly Effective Teachers in Diverse Middle Schools: Be Strict and Calm, Not Mean

    Science.gov (United States)

    McGregor, Katheryne L.

    2012-01-01

    This qualitative research study investigated and identified the classroom management strategies of 12 highly effective middle school teachers who served diverse student populations at two different school sites. In addition, this research explored the beliefs and experiences of 305 diverse middle school students regarding their experiences with…

  19. Mate choice for major histocompatibility complex complementarity in a strictly monogamous bird, the grey partridge (Perdix perdix)

    Czech Academy of Sciences Publication Activity Database

    Rymešová, D.; Králová, Tereza; Promerová, Marta; Bryja, Josef; Tomášek, Oldřich; Svobodová, J.; Šmilauer, P.; Šálek, M.; Albrecht, Tomáš

    2017-01-01

    Roč. 14, č. 1 (2017), č. článku 9. ISSN 1742-9994 R&D Projects: GA ČR GA206/08/1281 Institutional support: RVO:68081766 Keywords : Grey partridge * Mate choice * MHC genes * Ornaments * Sexual selection * Social monogamy * Inbreeding avoidance Subject RIV: EG - Zoology OBOR OECD: Zoology Impact factor: 2.781, year: 2016

  20. Probing the redox metabolism in the strictly anaerobic, extremely thermophilic, hydrogen-producing Caldicellulosiruptor saccharolyticus using amperometry

    DEFF Research Database (Denmark)

    Kostesha, Natalie; Willquist, Karin; Emnéus, Jenny

    2011-01-01

    Changes in the redox metabolism in the anaerobic, extremely thermophilic, hydrogen-forming bacterium Caldicellulosiruptor saccharolyticus were probed for the first time in vivo using mediated amperometry with ferricyanide as a thermotolerant external mediator. Clear differences in the intracellul...

  1. A note on finite-scale Navier–Stokes theory: The case of constant viscosity, strictly adiabatic flow

    International Nuclear Information System (INIS)

    Jordan, P.M.; Keiffer, R.S.

    2015-01-01

    We investigate the “piston problem” for the case of a viscous, but non-thermally conducting, gas with constant transport coefficients under the recently introduced generalization of the Navier–Stokes (NS) equations known as the finite-scale Navier–Stokes (FSNS) equations. Along with determining and analyzing the integral curves of the resulting kink-type traveling wave solutions (TWS)s, the present study also reveals the importance of the bulk viscosity vis-a-vis this special case of FSNS theory and highlights the impact that averaging has on the structure of the shock profile

  2. Gene function analysis in environmental isolates: The nif regulon of the strict iron oxidizing bacterium Leptospirillum ferrooxidans

    Science.gov (United States)

    Parro, Víctor; Moreno-Paz, Mercedes

    2003-01-01

    A random genomic library from an environmental isolate of the Gram-negative bacterium Leptospirillum ferrooxidans has been printed on a microarray. Gene expression analysis was carried out with total RNA extracted from L. ferrooxidans cultures in the presence or absence of ammonium as nitrogen source under aerobic conditions. Although practically nothing is known about the genome sequence of this bacterium, this approach allowed us the selection and sequencing of only those clones bearing genes that showed an altered expression pattern. By sequence comparison, we have identified most of the genes of nitrogen fixation regulon in L. ferrooxidans, like the nifHDKENX operon, encoding the structural components of Mo-Fe nitrogenase; nifSU-hesB-hscBA-fdx operon, for Fe-S cluster assembly; the amtB gene (ammonium transporter); modA (molybdenum ABC type transporter); some regulatory genes like ntrC, nifA (the specific activator of nif genes); or two glnB-like genes (encoding the PII regulatory protein). Our results show that shotgun DNA microarrays are very powerful tools to accomplish gene expression studies with environmental bacteria whose genome sequence is still unknown, avoiding the time and effort necessary for whole genome sequencing projects. PMID:12808145

  3. Strict mast fruiting for a tropical dipterocarp tree: a demographic cost–benefit analysis of delayed reproduction and seed predation

    NARCIS (Netherlands)

    Visser, M.D.; Jongejans, E.; Breugel, van M.; Zuidema, P.A.; Chen, Y.Y.; Kassim, A.R.; Kroon, de H.

    2011-01-01

    1. Masting, the production of large seed crops at intervals of several years, is a reproductive adaptation displayed by many tree species. The predator satiation hypothesis predicts that starvation of seed predators between mast years and satiation during mast years decreases seed predation and thus

  4. [How an outbreak of MRSA in Gothenburg was eliminated: by strict hygienic routines and massive control-culture program].

    Science.gov (United States)

    Seeberg, Staffan; Larsson, Leif; Welinder-Olsson, Christina; Sandberg, Torsten; Skyman, Eva; Bresky, Bo; Lindqvist, Anna; van Raalte, Margaretha

    2002-08-08

    The largest single-strain outbreak of methicillin resistant Staphylococcus aureus (MRSA) in Scandinavia so far occurred at Sahlgrenska University Hospital in Western Sweden 1997-2000. The strain identified was identical to the UK EMRSA-16 strain. 147 patients at 36 different wards became colonised or infected. Established routines for infection control had to be revised. The endemic situation necessitated an MRSA screening programme in October 1999 for all former hospital patients on re-admission. Since May 2000 no patient has been found with the outbreak strain at Sahlgrenska University Hospital.

  5. Synthesis of nanoparticles in a flame aerosol reactor with independent and strict control of their size, crystal phase and morphology

    Energy Technology Data Exchange (ETDEWEB)

    Jiang Jingkun; Chen, D-R; Biswas, Pratim [Aerosol and Air Quality Research Laboratory, Department of Energy, Environmental and Chemical Engineering, Washington University in St Louis, Campus Box 1180, St Louis, MO 63130 (United States)

    2007-07-18

    A flame aerosol reactor (FLAR) was developed to synthesize nanoparticles with desired properties (crystal phase and size) that could be independently controlled. The methodology was demonstrated for TiO{sub 2} nanoparticles, and this is the first time that large sets of samples with the same size but different crystal phases (six different ratios of anatase to rutile in this work) were synthesized. The degree of TiO{sub 2} nanoparticle agglomeration was determined by comparing the primary particle size distribution measured by scanning electron microscopy (SEM) to the mobility-based particle size distribution measured by online scanning mobility particle spectrometry (SMPS). By controlling the flame aerosol reactor conditions, both spherical unagglomerated particles and highly agglomerated particles were produced. To produce monodisperse nanoparticles, a high throughput multi-stage differential mobility analyser (MDMA) was used in series with the flame aerosol reactor. Nearly monodisperse nanoparticles (geometric standard deviation less than 1.05) could be collected in sufficient mass quantities (of the order of 10 mg) in reasonable time (1 h) that could be used in other studies such as determination of functionality or biological effects as a function of size.

  6. Kidney function during 12 months of strict metabolic control in insulin-dependent diabetic patients with incipient nephropathy

    DEFF Research Database (Denmark)

    Feldt-Rasmussen, B; Mathiesen, E R; Hegedüs, L

    1986-01-01

    Thirty-six patients with insulin-dependent diabetes mellitus who had Albustix-negative urine but elevated urinary albumin excretion (30 to 300 mg per 24 hours) were matched in pairs according to their urinary albumin level, blood glycosylated hemoglobin level, and sex and assigned randomly...... in all patients during insulin infusion, but no consistent change was observed in the control group. No significant change was observed in the glomerular filtration rate. Our data suggest that the pathologic processes causing microalbuminuria in early renal disease are not reversed during 12 months...

  7. Outcome of strict implementation of infection prevention control measures during an outbreak of Middle East respiratory syndrome.

    Science.gov (United States)

    El Bushra, Hassan E; Al Arbash, Hussain A; Mohammed, Mutaz; Abdalla, Osman; Abdallah, Mohamed N; Al-Mayahi, Zayid K; Assiri, Abdallah M; BinSaeed, Abdulaziz A

    2017-05-01

    The objective of this retrospective cohort study was to assess the impact of implementation of different levels of infection prevention and control (IPC) measures during an outbreak of Middle East respiratory syndrome (MERS) in a large tertiary hospital in Saudi Arabia. The setting was an emergency room (ER) in a large tertiary hospital and included primary and secondary MERS patients. Rapid response teams conducted repeated assessments of IPC and monitored implementation of corrective measures using a detailed structured checklist. We ascertained the epidemiologic link between patients and calculated the secondary attack rate per 10,000 patients visiting the ER (SAR/10,000) in 3 phases of the outbreak. In phase I, 6 primary cases gave rise to 48 secondary cases over 4 generations, including a case that resulted in 9 cases in the first generation of secondary cases and 21 cases over a chain of 4 generations. During the second and third phases, the number of secondary cases sharply dropped to 18 cases and 1 case, respectively, from a comparable number of primary cases. The SAR/10,000 dropped from 75 (95% confidence interval [CI], 55-99) in phase I to 29 (95% CI, 17-46) and 3 (95% CI, 0-17) in phases II and III, respectively. The study demonstrated salient evidence that proper institution of IPC measures during management of an outbreak of MERS could remarkably change the course of the outbreak. Copyright © 2017 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  8. Changes in Smoking Behavior Following a Strict No-Smoking Policy in U.S. Navy Recruit Training

    Science.gov (United States)

    1993-08-01

    Smoking and Health. DHHS Publication No. (CDC) 87-8396, 1990. Wilcox, N.S., Prochaska , J.D., Velicer, W.F., & DiClemente , C.C. •1985). Subject...the "entry" survey and had an expanded section on attitudes regarding Na,, y smoking policy. Specific questionnaire measures are described below...not expected, given the number of studies that have associated education level with smoking status (US DHI-iS, 1990; Wilcox, Prochaska , Velicer

  9. Sponge-Associated Bacteria Are Strictly Maintained in Two Closely Related but Geographically Distant Sponge Hosts ▿ † ‡ §

    Science.gov (United States)

    Montalvo, Naomi F.; Hill, Russell T.

    2011-01-01

    The giant barrel sponges Xestospongia muta and Xestospongia testudinaria are ubiquitous in tropical reefs of the Atlantic and Pacific Oceans, respectively. They are key species in their respective environments and are hosts to diverse assemblages of bacteria. These two closely related sponges from different oceans provide a unique opportunity to examine the evolution of sponge-associated bacterial communities. Mitochondrial cytochrome oxidase subunit I gene sequences from X. muta and X. testudinaria showed little divergence between the two species. A detailed analysis of the bacterial communities associated with these sponges, comprising over 900 full-length 16S rRNA gene sequences, revealed remarkable similarity in the bacterial communities of the two species. Both sponge-associated communities include sequences found only in the two Xestospongia species, as well as sequences found also in other sponge species and are dominated by three bacterial groups, Chloroflexi, Acidobacteria, and Actinobacteria. While these groups consistently dominate the bacterial communities revealed by 16S rRNA gene-based analysis of sponge-associated bacteria, the depth of sequencing undertaken in this study revealed clades of bacteria specifically associated with each of the two Xestospongia species, and also with the genus Xestospongia, that have not been found associated with other sponge species or other ecosystems. This study, comparing the bacterial communities associated with closely related but geographically distant sponge hosts, gives new insight into the intimate relationships between marine sponges and some of their bacterial symbionts. PMID:21856832

  10. Sponge-Associated Bacteria Are Strictly Maintained in Two Closely Related but Geographically Distant Sponge Hosts ▿ † ‡ §

    OpenAIRE

    Montalvo, Naomi F.; Hill, Russell T.

    2011-01-01

    The giant barrel sponges Xestospongia muta and Xestospongia testudinaria are ubiquitous in tropical reefs of the Atlantic and Pacific Oceans, respectively. They are key species in their respective environments and are hosts to diverse assemblages of bacteria. These two closely related sponges from different oceans provide a unique opportunity to examine the evolution of sponge-associated bacterial communities. Mitochondrial cytochrome oxidase subunit I gene sequences from X. muta and X. testu...

  11. Infectious Gastroenteritis and the Need for Strict Contact Precaution Procedures in Adults Presenting in the Emergency Department

    DEFF Research Database (Denmark)

    Skyum, Florence; Andersen, Vibeke; Chen, Ming

    2018-01-01

    BACKGROUND: Acute infectious gastroenteritis requires contact precautions to prevent spreading. On acute admission the cause of diarrhoea is unknown, so the decision of whom to isolate has to be made on clinical information with a risk of inexpedient use of contact precautions. AIM: The aims...... of the study were to investigate how often gastroenteritis occurs, and thus the isolation indication has to be assessed, in Danish emergency departments, and how often patients have to remain on contact precaution according to the results of the faecal samples. METHODS: This Danish register based retrospective......: Among 66,885 acute admissions 4.3% patients had at least one feature of gastroenteritis: admission with a chief complaint of diarrhoea (1.6%); faecal sample microbiology examination (2.8%); discharged with a gastroenteritis diagnosis (1.7%). 19% of those who had a faecal sample tested were norovirus...

  12. Three months of strictly controlled daily endurance exercise reduces thrombin generation and fibrinolytic risk markers in younger moderately overweight men

    DEFF Research Database (Denmark)

    Gram, Anne Sofie; Bladbjerg, Else-Marie; Skov, Jane

    2015-01-01

    PURPOSE: Physical activity is associated with a decreased risk of cardiovascular disease, but dose dependency of long-term physical exercise on biomarkers within coagulation and fibrinolysis is unknown. We aimed to investigate effects of two doses of daily endurance exercise on biomarkers...... of 600 kcal/day (HIGH), 300 kcal/day (MOD), or to maintain their habitual lifestyle (CON). Fasting blood samples were collected before and after the intervention and analysed for thrombin generation (endogenous thrombin potential, ETP) and concentrations of tissue-type plasminogen activator (t......-PA), plasminogen activator inhibitor type 1 (PAI-1), and von Willebrand factor (vWF). RESULTS: We observed significant within-group decreases in ETP (MOD 7 %; HIGH 6 %) and in t-PA (MOD 22 %; HIGH 21 %) and PAI-1 (MOD 16 %; HIGH 32 %) in both training groups, and no changes in the CON group. At 3 months, between...

  13. Strict tropism for CD71+/CD234+human reticulocytes limits the zoonotic potential ofPlasmodium cynomolgi.

    Science.gov (United States)

    Kosaisavee, Varakorn; Suwanarusk, Rossarin; Chua, Adeline C Y; Kyle, Dennis E; Malleret, Benoit; Zhang, Rou; Imwong, Mallika; Imerbsin, Rawiwan; Ubalee, Ratawan; Sámano-Sánchez, Hugo; Yeung, Bryan K S; Ong, Jessica J Y; Lombardini, Eric; Nosten, François; Tan, Kevin S W; Bifani, Pablo; Snounou, Georges; Rénia, Laurent; Russell, Bruce

    2017-09-14

    Two malaria parasites of Southeast Asian macaques, Plasmodium knowlesi and P cynomolgi , can infect humans experimentally. In Malaysia, where both species are common, zoonotic knowlesi malaria has recently become dominant, and cases are recorded throughout the region. By contrast, to date, only a single case of naturally acquired P cynomolgi has been found in humans. In this study, we show that whereas P cynomolgi merozoites invade monkey red blood cells indiscriminately in vitro, in humans, they are restricted to reticulocytes expressing both transferrin receptor 1 (Trf1 or CD71) and the Duffy antigen/chemokine receptor (DARC or CD234). This likely contributes to the paucity of detectable zoonotic cynomolgi malaria. We further describe postinvasion morphologic and rheologic alterations in P cynomolgi -infected human reticulocytes that are strikingly similar to those observed for P vivax These observations stress the value of P cynomolgi as a model in the development of blood stage vaccines against vivax malaria.

  14. Effect of two years of strict metabolic control on progression of incipient nephropathy in insulin-dependent diabetes

    DEFF Research Database (Denmark)

    Feldt-Rasmussen, B; Mathiesen, E R; Deckert, T

    1986-01-01

    36 patients with insulin-dependent diabetes mellitus who had 'Albustix'-negative urine but raised urinary albumin excretion (30 to 300 mg/24 h) were randomly assigned to either remaining on conventional insulin treatment or continuous subcutaneous insulin infusion and followed up for 2 years...... albumin excretion rate above 300 mg/24 h in at least two of three 24 h urine collections) developed in 5 patients in the conventional-treatment group, but not in the insulin-infusion group (p less than 0.05, two-tailed). Fractional albumin clearance (mean and range X 10(7] increased in the conventional...

  15. La escuela y la escolaridad como objetos históricos: facetas y problemas de la historia de la educación - School and schooling as historical objects. facets and issues in history of education

    Directory of Open Access Journals (Sweden)

    Antonio Viñao Frago

    2011-03-01

    Full Text Available A ESCOLA COMO E A ESCOLARIDADE COMO OBJETOS HISTÓRICOS. FACETAS E PROBLEMAS DA HISTÓRIA DA EDUCAÇÃO Resumo Este texto analisa a escola, em sua perspectiva histórica, em um duplo sentido: como instituição educativa formal que engloba todos os centros docentes de todos os níveis e modalidades de ensino, e como uma atividade que se leva a cabo em um espaço e tempo específicos (os espaços e tempos escolares. Meu propósito é analisar alguns dos enfoques ou olhares desde com os quais os historiadores têm cercado a instituição escolar, quer dizer, a escola e a escolaridade como um fato social derivado da existência da instituição escolar. Palavras-chave: história da educação; escola e escolaridade; educação espanhola.   SCHOOL AND SCHOOLING AS HISTORICAL OBJECTS. FACETS AND ISSUES IN HISTORY OF EDUCATION Abstract This text deals with the school and the schooling. First, it outlines the traditional history or approach of both issues. After, it analyses, in a successive way, how the paradigms of the social history, sociocultural history and socio-critical history have influenced the history, and the way of looking, from the historical standpoint, at both the school institution and the schooling process. All these aspects are dealt with a particular attention to the concepts and ideas of the grammar of schooling, school cultures, the socio-critical approach, the problem of the divergences existing between the political and cultural periodisations and the notion of progress. Keywords: history of education; schooling process; grammar of schooling; school cultures.   LA ESCUELA Y LA ESCOLARIDAD COMO OBJETOS HISTÓRICOS: FACETAS Y PROBLEMAS DE LA HISTORIA DE LA EDUCACIÓN Resumen Este texto trata sobre la escuela y la escolaridad. Expone, primero, la historia o enfoque tradicional de las mismas. Después, de modo sucesivo, analiza cómo los paradigmas de la historia social, la historia socio-cultural y la historia socio-crítica han

  16. Army Drawdown and Restructuring: Background and Issues for Congress

    Science.gov (United States)

    2013-01-03

    worn-out leftovers from World War II.”9 The low personnel and equipment readiness levels in 1950 became apparent during the initially weak U.S. military...the Vietnam War in 1968, the Army grew to over 1,570,000 men and women . The conscripted Army of the Vietnam War had a disproportionate...these numbers. Characterizing the Pacific region, the Army notes three of the world’s largest economies (United States, China , Japan); four of the

  17. National power grid simulation capability : need and issues

    Energy Technology Data Exchange (ETDEWEB)

    Petri, Mark C. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2009-06-02

    On December 9 and 10, 2008, the Department of Homeland Security (DHS) Science and Technology Directorate sponsored a national workshop at Argonne National Laboratory to explore the need for a comprehensive modeling and simulation capability for the national electric power grid system. The workshop brought together leading electric power grid experts from federal agencies, the national laboratories, and academia to discuss the current state of power grid science and engineering and to assess if important challenges are being met. The workshop helped delineate gaps between grid needs and current capabilities and identify issues that must be addressed if a solution is to be implemented. This report is a result of the workshop and highlights power grid modeling and simulation needs, the barriers that must be overcome to address them, and the benefits of a national power grid simulation capability.

  18. War in Afghanistan: Strategy, Operations, and Issues for Congress

    Science.gov (United States)

    2011-03-09

    ANSF appreciate their U.S. counterparts because “we drink from the same canteen .”100 The U.S. government has consistently urged ISAF troop...Afghanistan’s forces: from basic training, to military branch schools , to service academies, and eventually to “war college” (senior service school ). In each

  19. Trends and Issues in U.S. Navy Manpower

    Science.gov (United States)

    1985-01-01

    A Methodology for Using Draft Lottery Data To Estimate Volunteers, by Christopher Jehn and LCdr. Hugh E. Carroll, July 1973. 12. Center for Naval...Carroll, and Cdr. Robert A. Stephen, July 1972. 15. Center for Naval Analyses, Study 1050, The Use of Reenlistment Bonuses, by Christopher Jehn, Samuel D...for Naval Analyses, Research Contribution 272, User’s Guide to the QUIKPA Y Model, by Robert F. Hale, LCdr. John P. Aucella, and Leslie A. McCandless

  20. Waging the Wrong War: Drug War Strategy and Issues

    Science.gov (United States)

    1992-04-15

    will be fitted with a thermal imaging system which will support investigative efforts aimed at indoor cannabis cultivation.12’ However, as the legal...focus on DoD’s intelligence, legal, and law enforcement capabilities, and how each impacts on the national drug strategy. 10 PART III INTELLIGENCE The...individual drug shipments but also have had a "deterrent" effect against drug production and trafficking operations.49 However, despite the growing

  1. Provision of genetic services in Europe: current practices and issues.

    Science.gov (United States)

    Godard, Béatrice; Kääriäinen, Helena; Kristoffersson, Ulf; Tranebjaerg, Lisbeth; Coviello, Domenico; Aymé, Ségolène

    2003-12-01

    This paper examines the professional and scientific views on the social, ethical and legal issues that impact on the provision of genetic services in Europe. Many aspects have been considered, such as the definition and the aims of genetic services, their organization, the quality assessment, public education, as well as the partnership with patients support groups and the multicultural aspects. The methods was primarily the analysis of professional guidelines, legal frameworks and other documents related to the organization of genetic services, mainly from Europe, but also from USA and international organizations. Then, the method was to examine the background data emerging from an updated report produced by the Concerted Action on Genetic Services in Europe, as well as the issues debated by 43 experts from 17 European countries invited to an international workshop organized by the European Society of Human Genetics Public and Professional Policy Committee in Helsinki, Finland, 8 and 9 September 2000. Some conclusions were identified from the ESHG workshop to arrive at outlines for optimal genetic services. Participants were concerned about equal accessibility and effectiveness of clinical genetic services, quality assessment of services, professional education, multidisciplinarity and division of tasks as well as networking. Within European countries, adherence to the organizational principles of prioritization, regionalization and integration into related health services would maximize equal accessibility and effectiveness of genetic actions. There is a need for harmonization of the rules involved in financial coverage of DNA tests in order to make these available to all Europeans. Clear guidelines for the best practice will ensure that the provision of genetic services develops in a way that is beneficial to its customers, be they health professionals or the public, especially since the coordination of clinical, laboratory and research perspectives within a single organizational structure permits a degree of coherence not often found in other specialties.

  2. Framework on Economical Implication and Issues of SADU Implementation

    Directory of Open Access Journals (Sweden)

    Florin Postolache

    2011-04-01

    Full Text Available Due to software which plays an increasingly role in everyday life, interaction betweenhumans and computers will increase in importance; therefore, the ability to support interactions forefficient re-use of experience is a major challenge for systems in the future. Trace Based Reasoningwill have a significant impact on applications sharing experience, when they are based on the web inparticular, since traces allow us to imagine several ways of interaction in systems and to combinemultiple modes of interaction in a single system. In the conducted study we aimed at developing anAssist System of Human Diagnostician (SADU, meaning that this system will have the humanknowledge and then information retrieved by interaction with humans at the SADU request.

  3. Using Phenomenology to Conduct Environmental Education Research: Experience and Issues

    Science.gov (United States)

    Nazir, Joanne

    2016-01-01

    Recently, I applied a phenomenological methodology to study environmental education at an outdoor education center. In this article, I reflect on my experience of doing phenomenological research to highlight issues researchers may want to consider in using this type of methodology. The main premise of the article is that phenomenology, with its…

  4. Career Development Trends and Issues in the United States.

    Science.gov (United States)

    Hansen, L. Sunny

    1993-01-01

    Discusses global economic, political, and social trends affecting the workplace, families, education, and gender roles. Depicts current career development programs and practices with children and young, midlife, and older adults. Presents current issues in schools, adult education, and business/industry for career development. (SK)

  5. Rural Non Farm Employment in Assam: Trends and Issues

    OpenAIRE

    Chandrama Goswami; Manisha Bhattacharyya

    2014-01-01

    This study explores the rural labour market in Assam. The Work Participation Rates (WPR) for males has increased during the period 1993-94 to 2009-10, whereas the same for females has been fluctuating around a lower level of 15 to 20 per cent. Thus, unemployment rates for females have been higher than males. A sector-wise distribution of workers shows that the proportion of males employed in the farm sector has been declining in favour of the Non-Farm Sector (NFS), while the females are more ...

  6. Coast Guard Polar Icebreaker Modernization: Background and Issues for Congress

    Science.gov (United States)

    2016-11-10

    nine missions supported by polar ice operations are search and rescue; maritime safety; aids to navigation; ice operations; marine environmental...operations are search and rescue; maritime safety; aids to navigation; ice operations; marine environmental protection; living marine resources...1 (+0 +1) 1 Japan 1 1 Australia 1 1 Chile 1 1 Latvia 1 1 South Korea 1 1 South Africa 1 1 Argentina 1 1

  7. Feedback implementation options and issues for B factory accelerators

    International Nuclear Information System (INIS)

    Fox, J.D.; Briggs, D.; Eisen, N.; Hindi, H.; Hosseini, W.; Oxoby, G.; Linscott, I.; Coiro, O.; Ghigo, A.; Serio, M.; Lambertson, G.; Voelker, F.

    1992-09-01

    The proposed B factory accelerator facilities will require active feedback systems to control multibunch instabilities. These feedback systems must operate in machines with thousands of circulating bunches and with short (2--4 ns) interbunch intervals. The functional requirements for transverse (betatron) and longitudinal (synchrotron) feedback systems are presented. Several possible implementation options are discussed and system requirements developed. Conceptual designs are presented for the PEP II transverse and longitudinal feedback systems

  8. Changes and Issues in the Validation of Experience

    Science.gov (United States)

    Triby, Emmanuel

    2005-01-01

    This article analyses the main changes in the rules for validating experience in France and of what they mean for society. It goes on to consider university validation practices. The way in which this system is evolving offers a chance to identify the issues involved for the economy and for society, with particular attention to the expected…

  9. Defence Policy in the Italian Republic: Frames and Issues

    Directory of Open Access Journals (Sweden)

    Nicola Labanca

    2011-01-01

    Full Text Available El artículo se centra en las relaciones cívico-militares en la República Italiana. El nuevo modelo democrático de relaciones entre las autoridades políticas y el ejército tenía una marcada continuidad con el pasado, al mismo tiempo que en la nueva república las Fuerzas Armadas gozaban de una notable autonomía. Se pueden distinguir diferentes fases en la política de defensa italiana. En la fase de reconstrucción (1945-48, el Estado Mayor decidió tener de nuevo un ejército numeroso donde primase la cantidad sobre los elementos cualitativos. La pertenencia a la OTAN y el más duro periodo de la Guerra Fría (1949-53 aceleraron la transformación de las Fuerzas Armadas italianas. Reticencias al papel limitado que imponía la OTAN a la autonomía nacional fueron superadas gracias a la conciencia de que la Alianza proporcionaba importantes medios y posibilitaba la abolición de las limitaciones militares del tratado de paz de 1947. En los años 1954-62, las Fuerzas Armadas se vieron obligadas a reducir muchas de sus expectativas, pero al mismo tiempo avanzaron notablemente en la modernización, en gran parte gracias a las ayudas de los EEUU. El Ejército de Tierra fue el primer beneficiario, a la que le siguieron las Fuerzas Aéreas y finalmente (1958, la Armada. Ello fue así por dos razones: La Armada era el servicio que a finales de la guerra se encontraba en la mejor situación, al mismo tiempo que era en el Mediterráneo precisamente donde la amenaza soviética se hacía menos sentir. Sin embargo el Ejército de Tierra se centraba todavía en el número de tropas, con un bajo número de unidades acorazadas o motorizadas. En esos años Italia igualmente inauguró su política nuclear. Desde mediados de los años 60 hasta mediados de los 70 las Fuerzas Armadas iniciaron la “ristrutturazione” (reforma de “reestructuración” requerida por la nueva estrategia de respuesta flexible de la OTAN que se aceleró en los años 1975-78. El final de la Guerra Fría impuso cambios drásticos: en 1997 la organización y los poderes del Estado Mayor (inter-servicios fueron reforzados, en el año 2000 las mujeres fueron admitidas en las Fuerzas Armadas y en el 2005 el servicio militar fue totalmente abolido. Las Fuerzas Armadas fueron notablemente reducidas y empezaron a ser desplegadas en muchas operaciones a larga distancia. La impresión general es sin embargo que las Fueras Armadas, debido a un bajo presupuesto, sufren de sobre-extensión y se enfrentan a diversas dificultades, dadas las misiones que les son asignadas.

  10. Organization, activities, and issues with particular emphasis on coal

    International Nuclear Information System (INIS)

    Cole, D.R.

    1992-01-01

    The paper discusses Colorado's coal industry; the Colorado Mining Association; lobbying and legislative actions; industry networking, information, and communications; coal issues and activities; and Colorado issues and activities. Some of the latter include: land reclamation of mined lands; oil and gas drilling and coal mine conflicts; wild and scenic river designations; general permitting of coal mining discharges; and coal mine land reclamation awards

  11. CYBERQUEER – MAJOR TOPICS AND ISSUES IN CURRENT RESEARCH

    Directory of Open Access Journals (Sweden)

    SIMONA RODAT

    2014-12-01

    Full Text Available The emergence of the opportunities opened by the internet raises also questions of interest for research regarding the extent to which these have an impact on the formations of non heterosexual life and on the experience of marginalised sexual identities. There have been different approaches in this regard and answers vary from optimistic and utopian appraisals concerning cyberspace in the early 90s to the more moderate and sceptic visions in the 2000s. Starting from this framework of debates, the present paper aims to explore the meaning of the term “cyberqueer”, including the theoretical context of its occurrence, to briefly highlight some critical considerations relating to cyberqueer research and to look over the main recurrent themes linked up with this concept, such as queer and cyberqueer identity, body and (disembodied practices and the forthcoming process of blurring the dividing boundaries between real/virtual, online/offline and public/private

  12. How is health a security issue? Politics, responses and issues.

    Science.gov (United States)

    Lo Yuk-ping, Catherine; Thomas, Nicholas

    2010-11-01

    In the closing decade of the 20th century the myriad challenges posed by infectious disease in a globalized environment began to be re-conceptualized as threats to national and human security. The most widely applied model for identifying and responding to such threats is securitization theory, as proposed by the Copenhagen School. Although its analytical framework is generally accepted, its utility remains contested; especially in non-European and non-state settings. The papers in this special edition have several aims: (1) to analyse ways by which Asian states and international organizations have identified health challenges as security threats, (2) to draw upon the securitization model as a way of understanding the full extent to which these states and international organizations have responded to the health threat, and (3) to identify areas where the theory might be strengthened so as to provide greater analytical clarity in areas of health security. This paper acts as a broad introduction to a set of papers on 'Unhealthy governance' and explores some of the key findings from the subsequent papers.

  13. Chemical Facility Security: Regulation and Issues for Congress

    National Research Council Canada - National Science Library

    Shea, Dana A; Tatelman, Todd B

    2007-01-01

    The Department of Homeland Security (DHS) has proposed security regulations for chemical facilities, implementing the statutory authority granted in the Homeland Security Appropriations Act, 2007 (P.L...

  14. Wild edible mushrooms in the Blue Mountains: resource and issues.

    Science.gov (United States)

    Catherine G. Parks; Craig L. Schmitt

    1997-01-01

    This paper reviews the wild mushroom resource of the Blue Mountains of northeastern Oregon and southeastern Washington and summarizes issues and concerns for regulation, monitoring, and management. Existing biological information on the major available commercial mushrooms in the area, with emphasis on morels, is presented. Brief descriptions of the most commonly...

  15. Elder Learning in Hong Kong: Policies, Programmes, Provisions, and Issues

    Science.gov (United States)

    Tam, Maureen

    2012-01-01

    This paper explores the notions of active ageing and elder learning in Hong Kong where a strategic approach to elderly education is applied by the government to encourage lifelong learning. The paper outlines the policy development and support for elder learning in Hong Kong in two distinct periods: pre-1997 and post-1997. The post-1997 period is…

  16. Development and issues of nuclear industry in Taiwan

    International Nuclear Information System (INIS)

    Kuangchi Liu

    1994-01-01

    Industrial and economic developments in Taiwan have achieved a so-called 'miracle' in the last decades. Endeavors by the private enterprise, prudent planning by the government, and the devoted efforts by the diligent and creative labor forces have been credited jointly with the result. To develop a sustainable nuclear industry in support of an efficient and safe power generation and other applications of nuclear energy in Taiwan, continuing efforts from the private industry, government and each individual of the nuclear industry will be required. In this paper, milestones of the past and major issues for future developments will be discussed

  17. Nuclear weapons modernization: Plans, programs, and issues for Congress

    Science.gov (United States)

    Woolf, Amy F.

    2017-11-01

    The United States is currently recapitalizing each delivery system in its "nuclear triad" and refurbishing many of the warheads carried by those systems. The plans for these modernization programs have raised a number of questions, both within Congress and among analysts in the nuclear weapons and arms control communities, about the costs associated with the programs and the need to recapitalize each leg of the triad at the same time. This paper covers four distinct issues. It begins with a brief review of the planned modernization programs, then addresses questions about why the United States is pursuing all of these modernization programs at this time. It then reviews the debate about how much these modernization programs are likely to cost in the next decade and considers possible changes that might reduce the cost. It concludes with some comments about congressional views on the modernization programs and prospects for continuing congressional support in the coming years.

  18. Promoting Athletic Participation for Students with Disabilities: Trends and Issues

    Science.gov (United States)

    Morey, Melissa; Ennis, Robin Parks; Katsiyannis, Antonis

    2018-01-01

    Engaging in physical activity is important for school-age children, as it promotes a healthy and active lifestyle. However, barriers to participation in physical education and athletics often prevent students with disabilities from engaging in these important activities. There are several legal precedents that should be considered as schools seek…

  19. Examination of Capital Murder Jurors' Deliberations: Methods and Issues

    Science.gov (United States)

    Price, Keith; Coleman, Susan; Byrd, Gary R.

    2014-01-01

    The study of capital juries remains a subject of critical interest for the public and for legislative and judicial policy makers as well as legal scholars and social scientists. Cowan, Thompson, and Ellsworth established one of the standard methodologies for examination of this topic in their 1984 seminal study by observing the subjects' debate…

  20. Information Technology R&D: Critical Trends and Issues.

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Office of Technology Assessment.

    This Office of Technology Assessment report on the current state of research and development in the telecommunications industry in the United States examines four specific areas of research as case studies: computer architecture, artificial intelligence, fiber optics, and software engineering. It discusses the structure and orientation of some…

  1. Unique topics and issues in rheumatology and clinical immunology.

    Science.gov (United States)

    Selmi, Carlo

    2014-08-01

    Clinicians are facing unexpected issues in everyday practice, and these may become counterintuitive or challenging. Illustrative examples are provided by the hypersensitivity to universally used immunosuppressants such as corticosteroids or antibiotics such as beta-lactam. Secondly, additional issues are represented by the discovery of new pathogenetic mechanisms involved in rheumatoid and psoriatic arthritis or other chronic inflammatory diseases, genomic susceptibility to enigmatic diseases such as giant cell arteritis, or the shared role of specific mediators such as semaphorins. Third, the therapeutic armamentarium has dramatically changed over the past decade following the introduction of biotechnological drugs, and new mechanisms are being proposed to reduce adverse events or increase the drug effectiveness, particularly on cardiovascular comorbidities. Finally, rare diseases continue to represent difficult cases, as for Cogan's syndrome, with limited literature available for clinical recommendations. For these reason, the present issue of Clinical Reviews in Allergy and Immunology is timely and dedicated to these and other unique topics in clinical immunology and allergy. The aim of this issue is thus to help clinicians involved in internal medicine as well as allergists and clinical immunologists while discussing new pathways that will prove important in the near future.

  2. Joint Light Tactical Vehicle (JLTV): Background and Issues for Congress

    Science.gov (United States)

    2017-01-10

    Lockheed Martin Corporation (Grand Prairie, TX); and Oshkosh Corporation (Oshkosh, WI). On September 3, 2013, the Army began JLTV testing at Aberdeen... body protection as the Mine-Resistant, Ambush-Protected All- Terrain Vehicle (M-ATV). DOD had planned to award two contracts for the EMD phase, which...LLC (South Bend, IN); Lockheed Martin Corporation (Grand Prairie, TX); and Oshkosh Corporation (Oshkosh, WI). The period of performance was for 27

  3. War in Afghanistan: Strategy, Military Operations, and Issues for Congress

    Science.gov (United States)

    2010-06-08

    Agribusiness Development Teams................................................................................. 56 A Civilian Surge...be good potential for drawing Hekmatyar away from the insurgent fight and into a constructive role.89 Others caution that his reputation for Islamic...U.S. officials as critical to security, governance and development. Agribusiness Development Teams Supplementing the work of battlespace owners

  4. Changes in the Arctic: Background and Issues for Congress

    Science.gov (United States)

    2017-01-05

    enlargement of an existing claim, to territorial sovereignty in Antarctica shall be asserted while the present Treaty is in force. Supporters of the Law of...economic ties with Canada, Norway, and Denmark; all four countries are members of NATO . Although the United States views Russia as an important partner in... enlargement ; six countries—China, India, Singapore, South Korea, Japan, and Italy—were approved for permanent observer status. 234 Prior to the meeting

  5. Spent fuel storage - dry storage options and issues

    International Nuclear Information System (INIS)

    Akins, M.J.

    2007-01-01

    The increase in the number of nuclear energy power generation facilities will require the ability to store the spent nuclear fuel for a long period until the host countries develop reprocessing or disposal options. Plants have storage pools which are closely associated with the operating units. These are excellent for short term storage, but require active maintenance and operations support which are not desirable for the long term. Over the past 25 years, dry storage options have been developed and implemented throughout the world. In recent years, protection against terrorist attack has become an increasing source of design objectives for these facilities, as well as the main nuclear plant. This paper explores the current design options of dry storage cask systems and examines some of the current design issues for above ground , in-ground, or below-ground storage of spent fuel in dry casks. (author)

  6. Worldwide overview of nuclear submarine decommissioning plans and issues

    International Nuclear Information System (INIS)

    Oelgaard, P.L.

    1995-06-01

    The number of nuclear propelled vessels that have reached the end of their useful life, is increasing. This raises the question of what to do with these vessels. In this paper the order of magnitude of the problem is first discussed, i.e. the number of nuclear ships built and the number already taken out of service. Next the problems of the first stages of decommissioning are discussed, i.e. the removal of the fuel and the preparation of the reactor parts for final disposal, including the amounts of radioactivity involved. Thirdly, the various methods of final disposal are considered, sea disposal, shallow land burial and deep land burial. Finally, the risks involved in nuclear submarine decommissioning are briefly discussed. (au)

  7. Operation Iraqi Freedom: Strategies, Approaches, Results, and Issues for Congress

    Science.gov (United States)

    2009-04-02

    Operations ( BESO ).56 In March 2009, the Army announced that new BESOs would deploy from Fort Bliss, TX, to Iraq and Afghanistan later in the year... BESOs , Army officials stressed, would not depart radically from the familiar BCT construct—they would “remain full-spectrum capable,” and would be “…a...56 Charmingly but surely unintentionally, the word “ beso ” means “kiss” in Spanish. 57 Kris Osborn, “New U.S. Army Unit Adds Stability

  8. American intergovernmental relations: foundations, perspectives, and issues, 5th ed.

    NARCIS (Netherlands)

    O'Toole, Laurence J.; Christensen, Robert K.

    2012-01-01

    With the addition of brand new co-editor, Robert Christensen, this trusted reader is back in a fresh and insightful fifth edition. To the general structure that has made American Intergovernmental Relations so enduring, the editors have added a new section that incorporates the importance of law and

  9. Environmental microbiology as a mosaic of explored ecosystems and issues.

    Science.gov (United States)

    Faure, Denis; Bonin, Patricia; Duran, Robert

    2015-09-01

    Microbes are phylogenetically (Archaea, Bacteria, Eukarya, and viruses) and functionally diverse. They colonize highly varied environments and rapidly respond to and evolve as a response to local and global environmental changes, including those induced by pollutants resulting from human activities. This review exemplifies the Microbial Ecology EC2CO consortium's efforts to explore the biology, ecology, diversity, and roles of microbes in aquatic and continental ecosystems.

  10. Steam generators regulatory practices and issues in Spain

    International Nuclear Information System (INIS)

    Mendoza, C.; Castelao, C.; Ruiz-Colino, J.; Figueras, J.M.

    1997-01-01

    This paper presents the actual status of Spanish Steam Generator tubes, actions developed by PWR plant owners and submitted to CSN, and regulatory activities related to tube degradation mechanisms analysis; NDT tube inspection techniques; tube, tubesheet and TSPs integrity studies; tube plugging/repair criteria; preventive and corrective measures including whole SGs replacement; tube leak measurement methods and other operational aspects

  11. Formats for Digital Preservation: A Review of Alternatives and Issues

    National Research Council Canada - National Science Library

    2007-01-01

    ...). This review of alternative formats and the issues related to them was undertaken in the interest of implementing best practices in information life-cycle management, to dispel any misunderstandings...

  12. Nuclear power plant alarm systems: Problems and issues

    International Nuclear Information System (INIS)

    O'Hara, J.M.; Brown, W.S.

    1991-01-01

    Despite the incorporation of advanced technology into nuclear power plant alarm systems, human factors problems remain. This paper identifies to be addressed in order to allow advanced technology to be used effectively in the design of nuclear power plant alarm systems. The operator's use and processing of alarm system information will be considered. Based upon a review of alarm system research, issues related to general system design, alarm processing, display and control are discussed. It is concluded that the design of effective alarm systems depends on an understanding of the information processing capabilities and limitations of the operator. 39 refs

  13. Modern role and issues of radiation therapy for benign diseases

    International Nuclear Information System (INIS)

    Miyashita, Tsuguhiro; Tateno, Atsushi; Kumazaki, Tatsuo

    1999-01-01

    Cases of radiation therapy for benign diseases have diminished in number because of recent alternative methods and knowledge about radiation carcinogenesis. In contrast to this tendency, our cases of benign diseases have recently increased. The facts made us reconsider today's radiation therapy of benign diseases. We reviewed 349 patients who were diagnosed as having benign tumors or non-neoplastic conditions and treated by radiation therapy in the past sixteen years. Analyzed items were the annual transition of treatment number, sorts of diseases, patients' age and sex, and the goal of therapy. Of all radiation therapy patients, benign diseases account for 9.26%. The annual percentages were 0.5%, 6.0%, 11.2% and 13.7% at intervals of five years since 1982. The majority was 246 post-operative irradiation for keloids (71%) and 41 pituitary adenomas (12%). Compared with malignant tumors, benign disease patients were statistically younger and female-dominant. Applications of radiation therapy in keloids and pituitary adenomas had definite goals, but were unclear in other rare diseases. Benign diseases should be treated by radiation therapy as the second or third option, provided the patients have serious symptoms and their diseases do not respond to other modalities. It seems to be widely accepted that favorite cases such as keloids and pituitary adenomas are treated by radiation therapy. But, optimal radiation therapies for other rare benign diseases have not been established. Therefore, the building of databases on radiation therapy on benign diseases should be pursued. Since benign disease patients were young and female-dominant and had many remaining years, their carcinogenicity potential should be considered. (author)

  14. Army Drawdown and Restructuring: Background and Issues for Congress

    Science.gov (United States)

    2014-02-28

    as “worn-out leftovers from World War II.” The low personnel and equipment readiness levels in Army Drawdown and Restructuring: Background and...grew to over 1,570,000 men and women . The conscripted Army of the Vietnam War had a disproportionate representation of lower-income and non- college

  15. Experiences with OHP and Issues for the Future

    DEFF Research Database (Denmark)

    Bouvin, Niels Olof

    2000-01-01

    The OHSWG has by now moved from specifications to running code. This is an important step, not only because this is the only way of maturing the specifications, but also because it strengthens the credibility of the OHSWG. Showing that the ideas expressed by the OHSWG can be implemented is howeve...... are living in interesting times. Based on the experiences of developing the Arakne Environment, the author attempts to point out some worthwhile directions for future work within the OHSWG....

  16. Problems and issues for short-haul air transportation.

    Science.gov (United States)

    Vittek, J. F., Jr.

    1972-01-01

    The problems of developing an efficient short-haul air system are not primarily technical, but economic and political. The key issues are whether the community will accept new and expanded air facilities, what standards of service the passengers will demand and how the system will evolve. The solutions recommended are national in scope and require the federal government to take a leading role.

  17. Defense Acquisition Reform: Background, Analysis, and Issues for Congress

    Science.gov (United States)

    2014-05-23

    press-center/press-releases/Pages/jl2197.aspx. 2 For purposes of this report, total obligations are defined as total direct obligations. Deflators for...Department of Defense, “Department of Defense Deflators – TOA by Category ‘Total Non- (continued...) Defense Acquisition Reform: Background...April 2013, p. 5. 37 The five largest 2012 defense budgets were China ($102.4B), United Kingdom ($60.8B), Russia ($59.9B), Japan ($59.4B), and

  18. Learning to Read Words: Theory, Findings, and Issues

    Science.gov (United States)

    Ehri, Linnea C.

    2005-01-01

    Reading words may take several forms. Readers may utilize decoding, analogizing, or predicting to read unfamiliar words. Readers read familiar words by accessing them in memory, called sight word reading. With practice, all words come to be read automatically by sight, which is the most efficient, unobtrusive way to read words in text. The process…

  19. Principles and issues in radiological ecological risk assessment.

    Science.gov (United States)

    Jones, Daniel; Domotor, Stephen; Higley, Kathryn; Kocher, David; Bilyard, Gordon

    2003-01-01

    This paper provides a bridge between the fields of ecological risk assessment (ERA) and radioecology by presenting key biota dose assessment issues identified in the US Department of Energy's Graded Approach for Evaluating Radiation Doses to Aquatic and Terrestrial Biota in a manner consistent with the US Environmental Protection Agency's framework for ERA. Current radiological ERA methods and data are intended for use in protecting natural populations of biota, rather than individual members of a population. Potentially susceptible receptors include vertebrates and terrestrial plants. One must ensure that all media, radionuclides (including short-lived radioactive decay products), types of radiations (i.e., alpha particles, electrons, and photons), and pathways (i.e., internal and external contamination) are combined in each exposure scenario. The relative biological effectiveness of alpha particles with respect to deterministic effects must also be considered. Expected safe levels of exposure are available for the protection of natural populations of aquatic biota (10 mGy d(-1)) and terrestrial plants (10 mGy d(-1)) and animals (1 mGy d(-1)) and are appropriate for use in all radiological ERA tiers, provided that appropriate exposure assumptions are used. Caution must be exercised (and a thorough justification provided) if more restrictive limits are selected, to ensure that the supporting data are of high quality, reproducible, and clearly relevant to the protection of natural populations.

  20. Principles and issues in radiological ecological risk assessment

    International Nuclear Information System (INIS)

    Jones, Daniel; Domotor, Stephen; Higley Kathryn; Kocher, David; Bilyard, Gordon

    2003-01-01

    This paper provides a bridge between the fields of ecological risk coefficients.variability o published particle-solution distribution coeffiissues identified in the US Department of Energy's Graded Approach fo Evaluating Radiation Doses to Aquatic and Terrestrial Biota in a manner consistent with the US Environmental Protection Agency's framework for ERA. Current radiological ERA methods and data are intended for use in protecting natural populations of biota, rather than individual members of a population. Potentially susceptible receptors include vertebrates and terrestrial plants One must ensure that all media, radionuclides (including short-lived radioactive decay products), types of radiations (i.e., alpha particles electrons, and photons), and pathways (i.e., internal and external contamination) are combined in each exposure scenario. The relative biological effectiveness of alpha particles with respect to deterministic effects must also be considered. Expected safe levels of exposure are available for the protection of natural populations of aquatic biota (10 mGy d -1 ) and terrestrial plants (10 mGy d -1 ) and animals (1 mGy d -1 ) and are appropriate for use in all radiological ERA tiers, provided that appropriate exposure assumptions are used. Caution must be exercised (and a thorough justification provided) if more restrictive limits are selected, to ensure that the supporting data are of high quality, reproducible, and clearly relevant to the protection of natural populations

  1. Changes in the Arctic: Background and Issues for Congress

    Science.gov (United States)

    2013-04-25

    States and Europe in 2009/2010 and in Europe in 2011/2012;33 and Indian summer monsoons and droughts . Hence, changing climate in the Arctic...protection against waterborne diseases.182 Changes in Arctic indigenous cultures may increase mental stress and behavioral problems.183 The response...2012 Chicago Summit – likely at the insistence of Canada. See “NATO in the Arctic: Challenges and Opportunities,” by Luke Coffee , Heritage

  2. Natural product-based nanomedicine: recent advances and issues.

    Science.gov (United States)

    Watkins, Rebekah; Wu, Ling; Zhang, Chenming; Davis, Richey M; Xu, Bin

    2015-01-01

    Natural products have been used in medicine for many years. Many top-selling pharmaceuticals are natural compounds or their derivatives. These plant- or microorganism-derived compounds have shown potential as therapeutic agents against cancer, microbial infection, inflammation, and other disease conditions. However, their success in clinical trials has been less impressive, partly due to the compounds' low bioavailability. The incorporation of nanoparticles into a delivery system for natural products would be a major advance in the efforts to increase their therapeutic effects. Recently, advances have been made showing that nanoparticles can significantly increase the bioavailability of natural products both in vitro and in vivo. Nanotechnology has demonstrated its capability to manipulate particles in order to target specific areas of the body and control the release of drugs. Although there are many benefits to applying nanotechnology for better delivery of natural products, it is not without issues. Drug targeting remains a challenge and potential nanoparticle toxicity needs to be further investigated, especially if these systems are to be used to treat chronic human diseases. This review aims to summarize recent progress in several key areas relevant to natural products in nanoparticle delivery systems for biomedical applications.

  3. National All-Age Career Guidance Services: Evidence and Issues

    Science.gov (United States)

    Watts, A. G.

    2010-01-01

    The three major national all-age career guidance services--in New Zealand, Scotland and Wales--have been reviewed using an adaptation of the methodology adopted in the OECD Career Guidance Policy Review. The main features of the three services are summarised, and some key differences and distinctive strengths are outlined. The alternative approach…

  4. [Cardiovascular disease and aircraft transportation: specificities and issues].

    Science.gov (United States)

    Touze, Jean-Étienne; Métais, Patrick; Zawieja, Philippe

    2012-02-01

    With the development of air transport and travel to distant destinations, the number of passengers and elderly passengers on board increases each year. In this population, cardiovascular events are a major concern. Among medical incidents occurring in-flight they are second-ranked (10%) behind gastrointestinal disorders (25%). Their occurrence may involve life-threatening events and require resuscitation, difficult to perform during flight or in a precarious health environment. Coronary heart disease and pulmonary thromboembolic disease are the most serious manifestations. They are the leading cause of hospitalization in a foreign country and sudden cardiac death occurring during or subsequent to the flight. Their occurrence is explained on aircraft by hypoxia, hypobaria and decreased humidity caused by cabin pressurization and upon arrival by a different environmental context (extreme climates, tropical diseases). Moreover, the occurrence of a cardiovascular event during flight can represent for the air carrier a major economic and logistic problem when diversion occurred. Furthermore, the liability of the practitioner passenger could be involved according to airlines or to the country in which the aircraft is registered. In this context, cardiovascular events during aircraft transportation can be easily prevented by identifying high risk patients, respect of cardiovascular indications to travel, the implementation of simple preventive measures and optimization of medical equipment in commercial flights. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  5. Design choices and issues in fixed-target B experiments

    International Nuclear Information System (INIS)

    Camilleri, L.

    1993-01-01

    The main priority of any experiment on B physics in the years to come will be an endeavour to observe CP violation in the B sector. Such measurements imply the following requirements of the experiment. Trigger: a muon trigger will be sensitive to J/ψ reactions and muon tags; an electron trigger will double the number of lepton events; in order to include kaon tags and self-tagging reactions, the experiment must not rely entirely on lepton triggers. Secondary Vertex triggers and hadron p T triggers should be included in order to have the maximum flexibility. Detector: vertex detector; particle identification; good momentum resolution; electromagnetic and hadronic calorimeters; muon detector. In addition the following issues have to be addressed: Collider or fixed-target mode? If fixed target, extracted beam or internal target? If internal target, gas jet or wire target? If a gas jet, hydrogen or a heavy gas? Beam pipe design. Silicon microvertex design and radiation damage. K s 0 decay path. Particle identification. Momentum resolution. Order of detectors. No single method stands out as the open-quotes obvious one.close quotes An extracted beam yields better vertex resolution and an internal target easier triggering. A flexible and diverse triggering scheme is of prime importance in order to be sensitive to as many reactions as possible, the experiment should not be limited to lepton triggers only. Proposed experiments (P867, HERA B) at existing machines will be invaluable for testing new devices and strategies for the LHC and SSC experiments

  6. Igoru Music and Issues of Leadership in Okpe | Idamoyibo ...

    African Journals Online (AJOL)

    Igoru is one of the oldest music genres in Okpe, performed by both men and women. Its primary roles are to represent the cultural identity of the Okpe, defend the ethos and territorial landmass, and the leadership question. It queries wanton sociomoral attitude, perversion, injustice, cruelty, and unnecessary associations ...

  7. Restructuring EPA's Libraries: Background and Issues for Congress

    National Research Council Canada - National Science Library

    Bearden, David M; Esworthy, Robert

    2007-01-01

    ...), expressing concerns about the continued availability of the agency's collections. Library professional associations and public interest groups raised similar questions about access to this information...

  8. Management of Slightly Contaminated Materials: Status and Issues

    International Nuclear Information System (INIS)

    Pescatore, C.

    2001-01-01

    Usually, when values in risk assessment are discussed, e.g., within RISCOM and VALDOR, it is said, that there are values behind the risk assessment by the experts and that these values are hidden within the basic assumptions made and are not easily visible, especially to the higher-level decision-makers. It is shown in this paper, that the opposite can also happen: the decision-makers, those that set the standards, may not be aware of the all the relevant facts or they may ignore them because of how their institutional role and mandate are framed. In particular, it is important to realise that while nuclear power by-products are indeed specifically recognised for their radioactive hazard, radioactive products, by-products and 'wastes' also arise from practices other than nuclear power generation. As the threshold radioactivity levels for classifying a material as waste - or, what is the same, for allowing it for free release - become lower and lower, a larger and larger amount of by-products of human activities become concerned by the question 'is this radioactively dangerous material?' and how to deal with it. A holistic look at radioactivity both of man-made and natural origin needs to be implemented in order to claim and achieve consistency in the protection of public health and avoid issues of intra- and inter-generational equity

  9. Problems and Issues in New Media Education in Hong Kong.

    Science.gov (United States)

    Fung, Anthony Y. H.

    2000-01-01

    Claims the "dot com" trend has pushed new media education to go more technical. Suggests that new media education (including the Internet, e-commerce, multimedia production, and other computer-related communication) refocus on the communicative dimension and new media management. Argues that only based on this understanding can…

  10. Research trends and issues in informal science education

    Science.gov (United States)

    Pinthong, Tanwarat; Faikhamta, Chatree

    2018-01-01

    Research in informal science education (ISE) become more interesting area in science education for a few decades. The main purpose of this research is to analyse research articles in 30 issues of top three international journals in science education; Journal of Research in Science Teaching, Science Education, and the International Journal of Science Education. The research articles during 2007 and 2016 were reviewed and analysed according to the authors' nationality, informal science education's research topics, research paradigms, methods of data collection and data analysis. The research findings indicated that there were 201 published papers related to informal science education, successfully submitted by 469 authors from 27 different countries. In 2008, there was no article related to informal science education. Statistical analyses showed that authors from USA are the most dominant, followed by UK and Israel. The top three ISE's research topics most frequently investigated by the researchers were regarding students' informal learning, public understanding in science, and informal perspectives, policies and paradigms. It is also found that theoretical framework used in informal science education which is becoming more strongly rooted is in a mix of the sociocultural and constructivist paradigms, with a growing acceptance of qualitative research methods and analyses.

  11. Human milk banking-facts and issues to resolve

    NARCIS (Netherlands)

    W.E. Corpeleijn (Willemijn); M. Vermeulen (Mark); I. van Vliet (Ineke); C. Kruger (Caroline); J.B. van Goudoever (Hans)

    2010-01-01

    textabstractThe number of human milk banks is increasing worldwide. Although the beneficial effects of feeding premature infants with their mother's milk are well documented, less is known about the effects of feeding these infants with pasteurized donor milk. We propose a randomized trial comparing

  12. Initial MPTS study results: Design considerations and issues

    Science.gov (United States)

    Maynard, O. E.

    1980-12-01

    One of the key issues identified during investigations of microwave power transmission systems from 1965 to 1976 was the need to assure that the billions of diodes on ground-based rectennas are sufficiently reliable to support long life times of approximately 30 years. Major systems studies conducted focused on waveguides; radio frequency interference and biological considerations; the relationship between performance, weight, and cost; risk assessment; crossed field directional amplifier noise; a 48 kW klystron; effects of the environment on propagation and phase control; rectenna technology; a rationale for the ground power density region; alternate technologies for orbital assembly; ionospheric effects and phase control; and reception conversion (rf to dc collector/converter).

  13. Rural Non Farm Employment in Assam: Trends and Issues

    Directory of Open Access Journals (Sweden)

    Chandrama Goswami

    2014-06-01

    Full Text Available This study explores the rural labour market in Assam. The Work Participation Rates (WPR for males has increased during the period 1993-94 to 2009-10, whereas the same for females has been fluctuating around a lower level of 15 to 20 per cent. Thus, unemployment rates for females have been higher than males. A sector-wise distribution of workers shows that the proportion of males employed in the farm sector has been declining in favour of the Non-Farm Sector (NFS, while the females are more concentrated in the farm sector. Thus, females stand in a more disadvantageous situation in the rural labour market as indicated by their low WPR, higher unemployment rates and low level of diversification into NFS. However, gender equality is necessary for growth. This is more so with regard to education and employment. India has introduced the concept of inclusive growth in the Eleventh Five Year Plan. Inclusive growth ensures opportunities for all sections of the population, with a special emphasis on the poor, particularly women and young people, who are most likely to be marginalised. A rapidly growing population in India has not only increased the size of the rural labour force but has also led to fragmentation of land holdings. Thus, this sector alone cannot create additional employment opportunities, even in high growth agriculture states of India. This has led to the growth of a vibrant non-farm sector. The study comes up with the suggestion that the NFS, with its greater potential of employment generation, can not only solve the unemployment problem, but can also lead to the increased access of women to resources and employment opportunities.

  14. Carbon footprint of Canadian dairy products: calculations and issues.

    Science.gov (United States)

    Vergé, X P C; Maxime, D; Dyer, J A; Desjardins, R L; Arcand, Y; Vanderzaag, A

    2013-09-01

    The Canadian dairy sector is a major industry with about 1 million cows. This industry emits about 20% of the total greenhouse gas (GHG) emissions from the main livestock sectors (beef, dairy, swine, and poultry). In 2006, the Canadian dairy herd produced about 7.7 Mt of raw milk, resulting in about 4.4 Mt of dairy products (notably 64% fluid milk and 12% cheese). An integrated cradle-to-gate model (field to processing plant) has been developed to estimate the carbon footprint (CF) of 11 Canadian dairy products. The on-farm part of the model is the Unified Livestock Industry and Crop Emissions Estimation System (ULICEES). It considers all GHG emissions associated with livestock production but, for this study, it was run for the dairy sector specifically. Off-farm GHG emissions were estimated using the Canadian Food Carbon Footprint calculator, (cafoo)(2)-milk. It considers GHG emissions from the farm gate to the exit gate of the processing plants. The CF of the raw milk has been found lower in western provinces [0.93 kg of CO2 equivalents (CO2e)/L of milk] than in eastern provinces (1.12 kg of CO2e/L of milk) because of differences in climate conditions and dairy herd management. Most of the CF estimates of dairy products ranged between 1 and 3 kg of CO2e/kg of product. Three products were, however, significantly higher: cheese (5.3 kg of CO2e/kg), butter (7.3 kg of CO2e/kg), and milk powder (10.1 kg of CO2e/kg). The CF results depend on the milk volume needed, the co-product allocation process (based on milk solids content), and the amount of energy used to manufacture each product. The GHG emissions per kilogram of protein ranged from 13 to 40 kg of CO2e. Two products had higher values: cream and sour cream, at 83 and 78 kg of CO2e/kg, respectively. Finally, the highest CF value was for butter, at about 730 kg of CO2e/kg. This extremely high value is due to the fact that the intensity indicator per kilogram of product is high and that butter is almost exclusively fat. Protein content is often used to compare the CF of products; however, this study demonstrates that the use of a common food component is not suitable as a comparison unit in some cases. Functionality has to be considered too, but it might be insufficient for food product labeling because different reporting units (adapted to a specific food product) will be used, and the resulting confusion could lead consumers to lose confidence in such labeling. Therefore, simple units might not be ideal and a more comprehensive approach will likely have to be developed. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  15. Restructuring EPA's Libraries: Background and Issues for Congress

    National Research Council Canada - National Science Library

    Bearden, David M; Esworthy, Robert

    2007-01-01

    ..., $2.0 million of which was attributed mainly to these closures. EPA reports that the closings are part of its efforts to restructure its libraries to respond to the increasing use of the Internet to access its collections...

  16. Department of Defense Energy Initiatives: Background and Issues for Congress

    Science.gov (United States)

    2012-12-10

    efforts to improve the energy efficiency of its buildings and installations, reduce consumption, mitigate its carbon footprint , invest in renewable...fuel data, provided March 6, 2012. The remainder is used by other missions, such as special forces and combat search and rescue. 16 Oliver Fritz...equipment, and to illustrate potential systems’ logistical footprints . Section 332(c) of P.L. 110-417 states that “The Secretary of Defense shall require

  17. Orphan drugs: trends and issues in drug development.

    Science.gov (United States)

    Rana, Proteesh; Chawla, Shalini

    2018-04-12

    Research in rare diseases has contributed substantially toward the current understanding in the pathophysiology of the common diseases. However, medical needs of patients with rare diseases have always been neglected by the society and pharmaceutical industries based on their small numbers and unprofitability. The Orphan Drug Act (1983) was the first serious attempt to address the unmet medical needs for patients with rare diseases and to provide impetus for the pharmaceutical industry to promote orphan drug development. The process of drug development for rare diseases is no different from common diseases but involves significant cost and infrastructure. Further, certain aspect of drug research may not be feasible for the rare diseases. The drug-approving authority must exercise their scientific judgment and ensure due flexibility while evaluating data at various stages of orphan drug development. The emergence of patent cliff combined with the government incentives led the pharmaceutical industry to realize the good commercial prospects in developing an orphan drug despite the small market size. Indeed, many drugs that were given orphan designation ended up being blockbusters. The orphan drug market is projected to reach $178 billion by 2020, and the prospects of research and development in rare diseases appears to be quite promising and rewarding.

  18. Establishment of Canada's National Forest Inventory: Approach and Issues

    Science.gov (United States)

    A. Y. Omule; Mark D. Gillis

    2005-01-01

    This paper describes Canada's National Forest Inventory (NFI) sampling design and implementation. It also describes issues related to annualizing the NFI using the approach of the U.S. Department of Agriculture Forest Service Enhanced Forest Inventory and Analysis program as a model. It concludes with an outline of plans to address the inventory annualization...

  19. Preferences for political decision-making processes and issue publics

    NARCIS (Netherlands)

    Wojcieszak, M.

    2014-01-01

    Research on public attitudes toward political decision-making has typically focused on politics in general. This study attends to issue-level as well as individual-level factors that can explain political process preferences. First, drawing on the classic distinction between easy and hard political

  20. Pedestrian-motorcycle collisions: associated risks and issues

    Directory of Open Access Journals (Sweden)

    Ariffin Aqbal Hafeez

    2017-01-01

    Full Text Available From the statistics, there are serious concerns over the relatively high number of fatal motor vehicle crashes involving pedestrianmotorcycle in Malaysia. The high number of motorcycle registration on road, compounded by its popularity as the major mode of transportation in the nation, imposes safety risk to pedestrians, as well as to other road users. Data from 1,626 related road crashes of Royal Malaysia Police (RMP for the 2009-2013 period were retrospectively collected via MIROS Road Accident Analysis and Database System (M-ROADS. The data were then analyzed via logistic regression method to determine associations between risks and injury severity in pedestrian-motorcycle collisions. The results indicate that five factors were significantly related to injury severity, which include age, location of body injury, as well as speed limit, road geometry and lighting condition of collision site. Subsequently, focus group discussions with stakeholders were also conducted to gather relevant data to identify related issues and suggestions on motorcycle safety technology with regards to collision with pedestrian.

  1. U.S.-Vietnam Relations: Background and Issues for Congress

    Science.gov (United States)

    2008-10-31

    the United States provided $3 million of humanitarian aid (mainly prosthetics and aid to abandoned or orphaned children ) for Vietnam; restored direct...Commissioner for Refugees; (3) resolve the issue of the estimated several thousand Amerasians (whose fathers are Americans and whose mothers are Vietnamese...adoptions of Vietnamese children , which Hanoi halted in 2002. Protesters, mainly Vietnamese-Americans, appeared at every stop on Khai’s trip. November

  2. EDUCATION QUALITY AND ISSUES OF PEDAGOGICAL STAFF TRAINING

    Directory of Open Access Journals (Sweden)

    Vladimir P. Borisenkov

    2015-01-01

    Full Text Available The aim of the investigation is to reveal the reasons of deterioration of education quality at the Soviet and Post-Soviet school and, adopting the best experience of the countries that are recognised as world leaders in education; to plan the solution ways to current problems and situation at the Russian school. Methods. The principle of a historicism that expresses the necessity of concrete historical studying of the public phenomena is put in a basis of methodology of the research conducted by the author; it includes pedagogical phenomena (in the course of its origin, its development and transformation, taking into account variety of its communications, dependences and mediations. The concrete methods used in work, are typical for theoretical research: the analysis, an estimation and reduction in system of the empirical and generalised material on the selected theme. Large corpus of the scientific literature is studied. The data of the published international researches on education in which our country is widely involved (PISA, TIMSS, and also the national researches undertaken in the USA, Great Britain and other countries are considered. Methods of expert estimations, and direct supervision of educational process in secondary and higher educational institutions are applied. Results. The general characteristic of evolution of quality of the Russian education is presented during the Soviet and Post-Soviet periods. The factors which have had negative influence on quality of school training during the various periods are revealed. The estimation of the reasons which have caused failures of school reforms, carried out in the USSR in the 60–80s and within two last decades in modern Russia is given. The concurrent important positive shifts in this sphere, taking place in the same years are noted. Results of the international researches on education (PISA and TIMSS are presented; the scoring of Russia among other states is defined, following the results of the testing of students revealing level of reading literacy, mathematical and natural-science competence. Scientific novelty. The author finds out the true reasons which have caused gradual decrease of quality indicators of education still long before disintegration of Soviet Union, aiming to overcome the settled representations and the stereotypes, concerning evolutions of school training quality in Russia. New elements of strategy of an education development in the countries which have become the powerful and leading nations in the given sphere are found out and considered based on the findings of the international researches. Practical significance. Perspective directions of preparation of the pedagogical personnel complying with the qualifying characteristics of modern requirements are allocated. Realisation of practical measures according to these directions and taking into account specificity of regions of Russia will promote training improvement of quality education in Russia that has the important strategic value for the future of our state. 

  3. Medicaid and Managed Care: Key Data, Trends, and Issues

    Science.gov (United States)

    ... only about 20% of total Medicaid spending on services. This is because disabled and elderly beneficiaries, who account for most Medicaid spending, largely remain in fee-for-service (FFS), and because expensive services, such as nursing ...

  4. Trends, Patterns and Issues of Child Malnutrition in Bangladesh ...

    African Journals Online (AJOL)

    ... education, knowledge about sound feeding practices and eating habits, growth monitoring and women supportive socio-cultural norms need to be given more emphasis to overcome the present situation. Key words: Child malnutrition, Health, Bangladesh, Child care, Food availability, Poverty, Education, Natural disaster.

  5. Changes in the Arctic: Background and Issues for Congress

    Science.gov (United States)

    2014-04-28

    involve the entire suite of species in an ecosystem (e.g., host plants might not move north (or up) as fast as their moth herbivores , nor as fast as...have adequate icebreaking capability to support research that advances fundamental understanding of the region and its evolution ,” and that “The

  6. Education of Females in China: Trends and Issues.

    Science.gov (United States)

    Liu, Jing-qui

    1998-01-01

    Describes a study that provides an overview of the status of Chinese female education. Argues that despite many positive changes in Chinese society, females still experience severe gender discrimination as a result of culture, local and large-scale economics, irregular geographical location, and lack of role models. Contains six data tables and 19…

  7. Trends and Issues of Women's Education in China

    Science.gov (United States)

    Liu, Jane; Carpenter, Marilyn

    2005-01-01

    China has a rich educational history dating back more than three thousand years, but women did not become part of the mainstream education system until the last sixty years. The Confucian ideology, which has been deeply rooted throughout Chinese history, confined females to an oppressed social status. Moreover, this historical ideology continues…

  8. U.S. Strategic Nuclear Forces: Background, Developments, and Issues

    Science.gov (United States)

    2017-02-10

    next 10 to 20 years. Each of these programs is likely to stress the budgets and financial capabilities of the services. Nevertheless, the Air Force...Aiming High: Boredom, Drugs, Low Morale. The millennials of the U.S. nuclear missile corps are struggling to stay on high alert for a nuclear Armageddon

  9. DOD Security Cooperation: An Overview of Authorities and Issues

    Science.gov (United States)

    2016-08-23

    establishment of co-production capacity in the United States for Israel’s Iron Dome rocket defense program. Only one authority, which permits the...provided for operations outside the U.S. land area only in emergency circumstances; a subsequent version permitted assistance to foreign governments, but...enforcement operations outside the U.S. land area requires joint approval of the Secretary of Defense, the Attorney General, and the Secretary of

  10. Library and information science practice in Nigeria: trends and issues

    African Journals Online (AJOL)

    It observes the trend in library and information science practice whereby the advent of new technologies has had a tremendous impact on the traditional service delivery; leading to some fundamental issues. These were discussed in relation to certain fundamental implications for the Nigerian library schools where future ...

  11. IGORU MUSIC AND ISSUES OF LEADERSHIP IN OKPE DR ...

    African Journals Online (AJOL)

    Mitch

    1999-06-04

    Warri had a fight on June 4, 1999, which was flashed on the cyberspace that evening as a joint operation between Ijaw and Urhobo in an effort to wipe out the Itsekiri. The Itsekiri. Survival Movement directly accused the Urhobo of engaging in “genocide'' and “ethnic cleansing'' while the Ugbajo Itsekiri, an aristocratic club of ...

  12. Establishment and issues of new educational system by nutrition teachers.

    Science.gov (United States)

    Maruya, Nobuko; Kaneda, Masayo; Namikawa, Shintaro; Nakajima, Tomoko; Tamon, Takako; Murai, Yoko

    2005-08-01

    The Japanese school lunch system, which has over 100 y of history, has gained world attention for its well-developed and steady system, healthy Japanese-style menus including rice, and educational programs utilizing the school lunch system. Meanwhile, risk factors of health among students have been continuously worsening for the past dozen years or so. Therefore, Japan had hastened to develop better educational programs utilizing the school lunch and nutritional teachers. Under such circumstances, the Japanese Diet passed a bill to amend the School Education Law (hereinafter called the Amendment) which includes the establishment of an educational system by nutrition teachers in May, 2004. This system will be enforced in April, 2005. This system by nutrition teachers in Japan is well organized in both the legal and administrative senses and is attracting domestic and international attention as an example of an educational measure to improve the dietary life of students. The reason for this article in English is the additional intention of enlightening other countries by showing the political promotion problems of educational administration agencies, educational contents of nutrition teachers and some issues of the new educational system by nutrition teachers.

  13. Political Justice, Schooling and Issues of Group Identity

    Science.gov (United States)

    Keddie, Amanda

    2014-01-01

    This article explores issues associated with schooling and political justice. Such issues are understood in light of the contention surrounding how Western schooling contexts might best represent marginalised groups--in ways that accord them a political voice. The significance of group identity politics is explored drawing on international debates…

  14. Department of Defense Energy Initiatives: Background and Issues for Congress

    Science.gov (United States)

    2012-07-20

    lighting technology at military facilities has demonstrated substantial energy efficiencies and cost savings. However, the Committee is aware that...limited to, photovoltaic panels, solar thermal roof coatings, rooftop direct use solar lighting technology , green roofs, and cool roofs. In an

  15. Navy Ship Deployments: New Approaches - Background and Issues for Congress

    National Research Council Canada - National Science Library

    O'Rourke, Ronald

    2004-01-01

    The Navy is implementing or experimenting with new kinds of naval formations, more flexible forward-deployment schedules, forward-homeporting additional Navy ships, and long-duration deployments with crew rotation...

  16. Learning to Spell Words: Findings, Theories, and Issues

    Science.gov (United States)

    Treiman, Rebecca

    2017-01-01

    There has been less research on how children learn to spell than on how they learn to read, but a good deal is now known about spelling development. This article reviews studies of normative development, beginning with children's early scribbles and proceeding to prephonological spelling involving letters, phonologically influenced invented…

  17. Current anthropogenes and issues of soil ecology of Kazakstan

    International Nuclear Information System (INIS)

    Bel'gibaev, M.E.; Faizov, K.Sh.

    1996-01-01

    Information on ecological condition of soils on the Kazakhstan territory is cited. Loss of soils fertility because of erosion, deflation and pollution by heavy metals has been registered almost in all regions. Total soil degradation conducts to its desertification and landscape destabilization. In particular, in West Kazakstan there is nuclear site 'Kapustin Yar' functioned more than 45 years. On the site with total area of 1.4 mil. ha there were 29 nuclear explosions carried out (19-underground, 10-atmosphere), 29 000 missiles were set off as well. In the result the vast territory of top-soil is contaminated by radionuclides, heavy metals, residues of missiles fuels. Today underground cavities, formed after nuclear explosions on the Azgir site, have used as depositories for storage of high contaminated biologically dangerous radioactive substances

  18. Canadian energy supply and demand 1993 - 2010: Trends and issues

    International Nuclear Information System (INIS)

    1994-07-01

    The National Energy Board has since 1959 prepared and maintained projections of energy supply requirements and has from time to time published reports on them. The objectives of this report are to provide a comprehensive 'all energy' market analysis and outlook to service as a standard of reference for all parties interested in Canadian energy issues; to provide a framework for public discussion on emerging energy issues of national importance and to monitor the prospects for the supply, demand and price of natural gas in Canada pursuant to the Market-Based Procedure for regulating. The focus being on the broad outlines of prospective energy market developments under different underlying assumptions about key variables. 7 tabs., 60 figs

  19. Operation Iraqi Freedom: Strategies, Approaches, Results, and Issues for Congress

    National Research Council Canada - National Science Library

    Dale, Catherine

    2008-01-01

    Operation Iraqi Freedom (OIF) was launched on March 20, 2003, with the immediate stated goal of removing Saddam Hussein's regime and destroying its ability to use weapons of mass destruction or to make them available to terrorists...

  20. Operation Iraqi Freedom: Strategies, Approaches, Results, and Issues for Congress

    National Research Council Canada - National Science Library

    Dale, Catherine

    2008-01-01

    Operation Iraqi Freedom (OIF) was launched on March 20,2003, with the immediate stated goal of removing Saddam Hussein's regime and destroying its ability to use weapons of mass destruction or to make them available to terrorists...

  1. Human Factors Implications and Issues in Network Enabled Operations

    Science.gov (United States)

    2006-08-28

    of the old verities no longer hold true. The technophiles argue that the US must do what is necessary to ensure its dominance in military... Hart and DeGaulle.” In Paret, ed., Makers of Modern Strategy, 598-623. Broad, William and Nicholas Wade. Betrayers of the Truth. New York: Simon

  2. Unmanned Aerial Vehicles: Background and Issues for Congress

    National Research Council Canada - National Science Library

    Geer, Harlan; Bolkcom, Christopher

    2005-01-01

    .... Furthermore, the military effectiveness of UAVs in recent conflicts such as Iraq (1990) and Kosovo (1999) opened the eyes of many to both the advantages and disadvantages provided by unmanned aircraft...

  3. Changes in the Arctic: Background and Issues for Congress

    Science.gov (United States)

    2016-05-12

    Arctic Council as a forum for facilitating Arctic states’ cooperation on myriad issues of mutual interest within its current mandate. 252...development, in the forms of resource extraction, adventure tourism , and trans-Arctic shipping drives much of the current maritime activity in the...Arctic Council should remain a high-level forum devoted to issues within its current mandate and not be transformed into a formal international

  4. Environmental governance as inclusion and exclusion of actors and issues

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard

    2016-01-01

    The chapter analyses recent governance in Denmark of the interaction between climate, energy and land use. Governance is seen as inclusion and exclusion of actors and their perspectives in decisions about problems and solutions. Inclusion and exclusion are discussed as decisions about members and...

  5. Nuclear power plant alarm systems: Problems and issues

    Energy Technology Data Exchange (ETDEWEB)

    O' Hara, J.M.; Brown, W.S.

    1991-01-01

    Despite the incorporation of advanced technology into nuclear power plant alarm systems, human factors problems remain. This paper identifies to be addressed in order to allow advanced technology to be used effectively in the design of nuclear power plant alarm systems. The operator's use and processing of alarm system information will be considered. Based upon a review of alarm system research, issues related to general system design, alarm processing, display and control are discussed. It is concluded that the design of effective alarm systems depends on an understanding of the information processing capabilities and limitations of the operator. 39 refs.

  6. Internet Medical Usage in Japan: Current Situation and Issues

    Science.gov (United States)

    Mitani, Hiroaki; Haruki, Yasuo; Ogushi, Youichi

    2001-01-01

    Internet use by physicians and patients has become very popular in Japan. Fifty percent of physicians use the Internet to search for medical and other information. Over the past year, 22% of patients used the Internet to obtain medical information. Because there are no restrictions within Japan on using Web sites to advertise medical treatment, information can be freely sent out, and over the past two or three years this practice has increased dramatically. Internet medical information provides information about illnesses and medications, and it helps improve the quality of life of patients and families. Yet, depending on the content of the information provided and the way this information is used, there is a potential negative side as well. On principle, users are responsible for the way information is used, but there is a need for information providers to consider users' safety and to make the information effective for use. Because there is no absolute standard for evaluating the value of medical information, it is necessary to establish a system that opens a dialogue with society and that continuously accumulates high-quality information through the collection of various evaluations, rather than rely on an established authority. For industries and organizations related to commercial pursuits, in particular, it is most effective to establish their own codes for ethical conduct, rather than rely on governmental regulations. At the same time, it is important to have a confirmation function to evaluate how goals set by the outside are being implemented. Aiming at establishing a framework for the Internet medical usage, the Japan Internet Medical Association (JIMA) was founded in 1998 by medical professionals, lawyers, researchers, consumer representatives, patients and their families. We propose a system that would combine feedback from users, who would take on the role of evaluators of the implementation of an ethical code, with a displayed mark that verifies the identity of the Web site. Objective evaluation of information is needed to ensure that users have the power to make choices. Medical experts or patient and family groups would assist in this task. The development of medical care will be promoted through patients and physicians' working together in the accumulation of shared resources for good medical care information. PMID:11720954

  7. Adult Education in American Society: Some Developments, Trends, and Issues.

    Science.gov (United States)

    Charters, Alexander N.

    1975-01-01

    A discussion of adult education in a changing American society is presented in the document. Section 1, Adult Education in American Society, examines societal changes and educational goals as well as the structure and organization of adult education programs. Section 2, The Delivery System of Adult Education, discusses: (1) the audience; (2)…

  8. Changes in the Arctic: Background and Issues for Congress

    Science.gov (United States)

    2016-12-07

    countries regarding the management of Arctic fish stocks. Changes in the Arctic could affect threatened and endangered species. Under the Endangered...Shelf Project. 48 Additional Points Some observers have suggested that a separate international legal regime be negotiated to address the changing ...circumstances in the Arctic. They maintain that these changing circumstances were not envisioned at the time UNCLOS was negotiated . Still others

  9. Federal Wildfire Activities. Current Strategy and Issues Needing Attention

    National Research Council Canada - National Science Library

    1999-01-01

    Concerned about the rising costs of preparing for and controlling wildfires, you asked us to provide information on how the Forest Service and the Bureau of Land Management manage their wildfire programs...

  10. Architecture Design Approaches and Issues in Cross Layer Systems

    DEFF Research Database (Denmark)

    Cattoni, Andrea Fabio; Sørensen, Troels Bundgaard; Mogensen, Preben

    2012-01-01

    Wireless communications are a fast grown part of the telecommunication market. While new types of traffic and challenges related to the wireless medium are appearing, the methodologies for designing system architectures are substantially remaining the same. Under the increasing pressure of market...... the traditional protocol stack design methodology. However, Cross Layer also carries a risk due to possibly unexpected and undesired effects. In this chapter we want to provide architecture designers with a set of tools and recommendations synthesized from an analysis of the state of art, but enriched...

  11. TRENDS AND ISSUES IN SAFE DRIVER ASSISTANCE SYSTEMS

    Directory of Open Access Journals (Sweden)

    Sadayuki TSUGAWA

    2006-01-01

    Full Text Available In recent years, ITS projects in Japan, Europe and the US have been characterized by a strong emphasis on safe driver assistance systems designed to prevent traffic accidents. As it has become clear that eradicating accidents will be impossible by means of vehicle passive safety and single-vehicle active safety efforts alone, research and development of systems for preventing accidents through road-vehicle cooperation and vehicle-vehicle cooperation have been promoted in Japan (ASV, AHS, Europe (PReVENT, SAFESPOT and the US (VII. The key to such technology is road-to-vehicle communications and inter-vehicle communications. On the other hand, a number of driver assistance systems have been brought to market, including lidar-based forward collision warnings, ACC, lane keeping support and drowsiness warnings, but their penetration rates in Japan are extremely low. Furthermore, one major challenge is that safe driver assistance systems based on road-vehicle and vehicle-vehicle cooperation are premised upon a high penetration rate. Finally, we introduce a system for improving driver acceptance of safe driver assistance systems based on driver monitoring and forward monitoring as well as cooperative driver assistance systems for elderly drivers, an issue now receiving attention in Japan.

  12. Coast Guard Cutter Procurement: Background and Issues for Congress

    Science.gov (United States)

    2016-09-16

    stabilized MK38 Mod 2, 25mm main gun ; improved sea keeping; and enhanced crew habitability. 28 The FRC program received approval from DHS to enter...Remains Unachievable, GAO-11-743, July 2011, p. 46. 46 The FMA Phase 1 and Phase 2 studies present acquisition and life-cycle ownership cost...aircraft. The study estimated the total ownership cost (i.e., procurement plus life- cycle O&S cost) of the objective fleet mix of cutters and aircraft at

  13. Evaluation of Airport Security Training Programs: Perspectives and Issues

    OpenAIRE

    Shim, Woohyun; Masacci, Fabio; De Gramatica, Martina; Tedeschi, Alessandra; Pollini, Alessandro

    2013-01-01

    While many governments and airport operators have emphasized the importance of security training and committed a large amount of budget to security training programs, the implementation of security training programs was not proactive but reactive. Moreover, most of the security training programs were employed as a demand or a trendchasing activity from the government. In order to identify issues in airport security training and to develop desirable security training procedures in ...

  14. Teaching Comparative Education: Trends and Issues Informing Practice

    Science.gov (United States)

    Kubow, Patricia K., Ed.; Blosser, Allison H., Ed.

    2016-01-01

    With chapter contributions from seminal scholars in the field of comparative and international education (CIE), this book examines the ways in which comparative education is being taught, or advocated for, in teacher education within higher education institutions worldwide. A particular concern raised by the authors--in locations as diverse as…

  15. The Logic and Issues of International Regional Tax Integration

    OpenAIRE

    Kudryashova, Ekaterina

    2016-01-01

    The article is devoted to the issues of international regional tax integration. The international economic integration has two mainstreams: global and regional economic integration. The global tax integration is concerned only with double taxation matters while the regional tax integration aims at procuring of four fundamental freedoms of common market and goes far beyond the elimination of double taxation. The legal solution for both global and regional international tax integration can not ...

  16. Natural product-based nanomedicine: recent advances and issues

    Directory of Open Access Journals (Sweden)

    Watkins R

    2015-09-01

    Full Text Available Rebekah Watkins,1,2,* Ling Wu,1,* Chenming Zhang,3–5 Richey M Davis,3,5,6 Bin Xu1,3 1Department of Biochemistry, 2Program in Nanoscience, 3Center for Drug Discovery, 4Department of Biological Systems Engineering, 5Institute for Critical Technology and Applied Science, 6Department of Chemical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA *These authors contributed equally to this work Abstract: Natural products have been used in medicine for many years. Many top-selling pharmaceuticals are natural compounds or their derivatives. These plant- or microorganism-derived compounds have shown potential as therapeutic agents against cancer, microbial infection, inflammation, and other disease conditions. However, their success in clinical trials has been less impressive, partly due to the compounds’ low bioavailability. The incorporation of nanoparticles into a delivery system for natural products would be a major advance in the efforts to increase their therapeutic effects. Recently, advances have been made showing that nanoparticles can significantly increase the bioavailability of natural products both in vitro and in vivo. Nanotechnology has demonstrated its capability to manipulate particles in order to target specific areas of the body and control the release of drugs. Although there are many benefits to applying nanotechnology for better delivery of natural products, it is not without issues. Drug targeting remains a challenge and potential nanoparticle toxicity needs to be further investigated, especially if these systems are to be used to treat chronic human diseases. This review aims to summarize recent progress in several key areas relevant to natural products in nanoparticle delivery systems for biomedical applications. Keywords: natural products, nanomedicine, drug delivery, bioavailability, targeting, controlled release

  17. Natural product-based nanomedicine: recent advances and issues

    Science.gov (United States)

    Watkins, Rebekah; Wu, Ling; Zhang, Chenming; Davis, Richey M; Xu, Bin

    2015-01-01

    Natural products have been used in medicine for many years. Many top-selling pharmaceuticals are natural compounds or their derivatives. These plant- or microorganism-derived compounds have shown potential as therapeutic agents against cancer, microbial infection, inflammation, and other disease conditions. However, their success in clinical trials has been less impressive, partly due to the compounds’ low bioavailability. The incorporation of nanoparticles into a delivery system for natural products would be a major advance in the efforts to increase their therapeutic effects. Recently, advances have been made showing that nanoparticles can significantly increase the bioavailability of natural products both in vitro and in vivo. Nanotechnology has demonstrated its capability to manipulate particles in order to target specific areas of the body and control the release of drugs. Although there are many benefits to applying nanotechnology for better delivery of natural products, it is not without issues. Drug targeting remains a challenge and potential nanoparticle toxicity needs to be further investigated, especially if these systems are to be used to treat chronic human diseases. This review aims to summarize recent progress in several key areas relevant to natural products in nanoparticle delivery systems for biomedical applications. PMID:26451111

  18. Ochratoxin A: Previous risk assessments and issues arising

    DEFF Research Database (Denmark)

    Walker, R.; Larsen, John Christian

    2005-01-01

    Ochratoxin A (OTA) causes nephropathy in all species tested with large sex and species differences in potency, pigs being most sensitive. It has been linked to Balkan endemic nephropathy (BEN) in humans. Embryotoxicity, teratogenicity, and immunotoxicity occur only at doses higher than those...

  19. Federal Wildfire Activities. Current Strategy and Issues Needing Attention

    National Research Council Canada - National Science Library

    1999-01-01

    .... Specifically, this report provides information on (1) the process the Forest Service and the Bureau of Land Management use to determine the amount of funds needed to prepare for fighting fires; (2...

  20. Ethical responsibilities in nursing: research findings and issues.

    Science.gov (United States)

    Cassidy, V R

    1991-01-01

    Discussions in the literature assert that nurses are becoming increasingly cognizant of their ethical responsibilities, but that they are often ill prepared to participate in ethical decision making. A review of selected research literature from 1970 to 1987 was undertaken to validate these assertions. A total of 12 studies related to ethical responsibilities was identified in the review; all studies were published between 1980 and 1987. The majority of studies were at the descriptive and exploratory levels and employed Kohlberg's cognitive theory of moral development as their conceptual framework. Significant findings related to educational level and ethical responsibilities were consistent across studies. Findings related to age and clinical experience were mixed; the effects of economic level, religion-religiosity, ethnicity, and other variables on ethical responsibilities were not significant. Issues raised in the light of the existing research include the use of Kohlberg's theory as a conceptual orientation in nursing groups and limited data on the reliability and validity of instruments used in measuring ethical constructs. Recommendations for future research on ethical responsibilities include the validation of Kohlberg's theory for nursing investigations, exploration of other frameworks for developing a multidimensional view of ethical responsibilities, and the use of qualitative research designs.