WorldWideScience

Sample records for strict performance requirements

  1. Study on Environment Performance Evaluation and Regional Differences of Strictly-Environmental-Monitored Cities in China

    Directory of Open Access Journals (Sweden)

    Ji Guo

    2017-12-01

    Full Text Available With the rapid economic growth and development, the problem of environmental pollution in China’s cities is becoming increasingly serious, and environmental pollution takes on a regional difference. There is, however, little comprehensive evaluation on the environmental performance and the regional difference of strictly-environmental-monitored cities in China. In this paper, the environmental performance of 109 strictly-environmental-monitored cities in China is evaluated in terms of natural performance, management performance, and scale performance by Data Envelopment Analysis (DEA, incorporating PM2.5 and PM10 as undesirable outputs. The empirical results show that: (1 At present, the natural performance is quite high, while the management performance is noticeably low for most cities. (2 The gap between the level of economic development and environmental protection among cities in China is large, and the scale efficiency of big cities is better than that of smaller cities. The efficiency value of large-scale cities such as Beijing, Shanghai, Guangzhou, Shenzhen, etc. is high, equaling 1; the value of smaller cities such as Sanmenxia, Baoding, Mudanjiang, and Pingdingshan is low, close to 0, indicating that big cities are characterized by high environmental efficiency. (3 From the perspective of region, the level of environmental performance in China is very uneven. For example, the environmental efficiency level of the Pan-Pearl River Delta region is superior to that of the Pan-Yangtze River region and the Bahia Rim region, whose values of environmental efficiency are 0.858, 0.658, and 0.622 respectively. The average efficiency of the Southern Coastal Economic Zone, Eastern Coastal Comprehensive Economic Zone, and the Comprehensive Economic Zone in the middle reaches of the Yangtze River is higher than that of other regions. Finally, corresponding countermeasures and suggestions are put forward. The method used in this paper is applicable

  2. A non-permselective membrane reactor for chemical processes normally requiring strict stoichiometric feed rates of reactants

    NARCIS (Netherlands)

    Sloot, H.J.; Versteeg, Geert; van Swaaij, Willibrordus Petrus Maria

    1990-01-01

    A novel type of membrane reactor with separated feeding of the reactants is presented for chemical processes normally requiring strict stoichiometric feed rates of premixed reactants. The reactants are fed in the reactor to the different sides of a porous membrane which is impregnated with a

  3. Pseudouridine synthase 1: a site-specific synthase without strict sequence recognition requirements

    Science.gov (United States)

    Sibert, Bryan S.; Patton, Jeffrey R.

    2012-01-01

    Pseudouridine synthase 1 (Pus1p) is an unusual site-specific modification enzyme in that it can modify a number of positions in tRNAs and can recognize several other types of RNA. No consensus recognition sequence or structure has been identified for Pus1p. Human Pus1p was used to determine which structural or sequence elements of human tRNASer are necessary for pseudouridine (Ψ) formation at position 28 in the anticodon stem-loop (ASL). Some point mutations in the ASL stem of tRNASer had significant effects on the levels of modification and compensatory mutation, to reform the base pair, restored a wild-type level of Ψ formation. Deletion analysis showed that the tRNASer TΨC stem-loop was a determinant for modification in the ASL. A mini-substrate composed of the ASL and TΨC stem-loop exhibited significant Ψ formation at position 28 and a number of mutants were tested. Substantial base pairing in the ASL stem (3 out of 5 bp) is required, but the sequence of the TΨC loop is not required for modification. When all nucleotides in the ASL stem other than U28 were changed in a single mutant, but base pairing was retained, a near wild-type level of modification was observed. PMID:22102571

  4. The LHC Continuous Cryostat Interconnections The Organization of a Logistically Complex Worksite Requiring Strict Quality Standards and High Output

    CERN Document Server

    Fessia, P; Bozzini, D; Cruikshank, P; Jacquemod, A; Maan, W; Musso, A; Oberli, L; Poncet, A; Russenschuck, Stephan; Savary, F; Struik, M; Tock, J Ph; Tommasini, D; Völlinger, C; Kotarba, A; Olek, S; Sulek, Z; Grimaud, A; Vaudaux, L

    2008-01-01

    The interconnections of the Large Hadron Collider (LHC) continuous cryostat have been completed in fall 2007: 1695 interconnections magnet to magnet and 224 interconnections between the continuous cryostat and the cryogenic distribution line have been executed along the 27 km of the LHC. The very tight schedule, the complexity of the interconnection sequence, the strict quality standards applied have required the creation of an ad hoc organization in order to steer and coordinate the activities on the worksite dispersed along the whole accelerator ring. The concatenation of construction and test phases carried out by CERN staff, CERN collaborating institutes and contractors have led to the necessity of a common approach and of a very effective information flow. In this paper, after having recalled the main technical challenges, we review the organizational choices that have been taken and we briefly analyze the development of the worksite in term of allocated resources and production.

  5. Strict confluent drawing

    Directory of Open Access Journals (Sweden)

    David Eppstein

    2016-01-01

    Full Text Available We define strict confluent drawing, a form of confluent drawing in which the existence of an edge is indicated by the presence of a smooth path through a system of arcs and junctions (without crossings, and in which such a path, if it exists, must be unique. We prove that it is NP-complete to determine whether a given graph has a strict confluent drawing but polynomial to determine whether it has an outerplanar strict confluent drawing with a fixed vertex ordering (a drawing within a disk, with the vertices placed in a given order on the boundary.

  6. Strictly convex renormings

    Czech Academy of Sciences Publication Activity Database

    Moltó, A.; Orihuela, J.; Troyanski, S.; Zizler, Václav

    2007-01-01

    Roč. 75, č. 3 (2007), s. 647-658 ISSN 0024-6107 R&D Projects: GA AV ČR IAA100190502 Institutional research plan: CEZ:AV0Z10190503 Keywords : strictly convex norms * lattice norm * quasi-diagonal sets Subject RIV: BA - General Mathematics Impact factor: 0.733, year: 2007

  7. Quine's "Strictly Vegetarian" Analyticity

    NARCIS (Netherlands)

    Decock, L.B.

    2017-01-01

    I analyze Quine’s later writings on analyticity from a linguistic point of view. In Word and Object Quine made room for a “strictly vegetarian” notion of analyticity. In later years, he developed this notion into two more precise notions, which I have coined “stimulus analyticity” and “behaviorist

  8. Efficient Strictness Analysis of Haskell

    DEFF Research Database (Denmark)

    Jensen, Kristian Damm; Hjæresen, Peter; Rosendahl, Mads

    1994-01-01

    Strictness analysis has been a living field of investigation since Mycroft's original work in 1980, and is getting increasingly significant with the still wider use of lazy functional programming languages. This paper focuses on an actual implementation of a strictness analyser for Haskell...

  9. Sequestration Coating Performance Requirements for ...

    Science.gov (United States)

    symposium paper The EPA’s National Homeland Security Research Center (NHSRC), in collaboration with ASTM International, developed performance standards for materials which could be applied to exterior surfaces contaminated by an RDD to mitigate the spread and migration of radioactive contamination.

  10. Species Protection in the European Union : How Strict is Strict?

    NARCIS (Netherlands)

    Schoukens, Hendrik; Bastmeijer, Kees; Born et al., Charles-Hubert

    2015-01-01

    European Union law to protect wild species of plants and animals is generally considered as ‘strict’. Opponents of nature conservation law often pick the species protection components of the EU Bird Directive and Habitat Directive as a prime example of an unnecessary strict regulatory scheme that

  11. Higher speed freight truck design : performance requirements.

    Science.gov (United States)

    2013-10-01

    This proposed requirements document combines a set of requirements for high-speed freight car truck design and performance : from the generally accepted standards in the U.S. Code of Federal Regulation (CFR), the Association of American Railroads : (...

  12. Strictness Analysis for Attribute Grammars

    DEFF Research Database (Denmark)

    Rosendahl, Mads

    1992-01-01

    interpretation of attribute grammars. The framework is used to construct a strictness analysis for attribute grammars. Results of the analysis enable us to transform an attribute grammar such that attributes are evaluated during parsing, if possible. The analysis is proved correct by relating it to a fixpoint...... semantics for attribute grammars. An implementation of the analysis is discussed and some extensions to the analysis are mentioned....

  13. Flexible or Strict Taxonomic Organization?

    DEFF Research Database (Denmark)

    Glückstad, Fumiko Kano; Mørup, Morten

    2012-01-01

    This work compares methods for constructing feature-based ontologies that are supposed to be used for culturally-specific knowledge transfer. The methods to be compared are the Terminological Ontology (TO) [1], a method of constructing ontology based on strict principles and rules, and the Infinite...... Relational Model (IRM) [2], a novel unsupervised machine learning method that learns multi-dimensional relations among concepts and features from loosely structured datasets. These methods are combined with a novel cognitive model, the Bayesian Model of Generalization (BMG) [3] that maps culturally...

  14. Comparison of energy performance requirements levels

    DEFF Research Database (Denmark)

    Spiekman, Marleen; Thomsen, Kirsten Engelund; Rose, Jørgen

    This summary report provides a synthesis of the work within the EU SAVE project ASIEPI on developing a method to compare the energy performance (EP) requirement levels among the countries of Europe. Comparing EP requirement levels constitutes a major challenge. From the comparison of for instance...... the present Dutch requirement level (EPC) of 0,8 with the present Flemish level of E80, it can easily be seen that direct comparison is not possible. The conclusions and recommendations of the study are presented in part A. These constitute the most important result of the project. Part B gives an overview...

  15. Extremely strict ideals in Banach spaces

    Indian Academy of Sciences (India)

    Motivated by the notion of an ideal introduced by Godefroy {\\it et al.} ({\\it Studia Math.} {\\bf 104} (1993) 13–59), in this article, we introduce and study the notion of an extremely strict ideal. For a Poulsen simplex K , we show that the space of affine continuous functions on K is an extremely strict ideal in the space of continuous ...

  16. Hyperbolic spaces are of strictly negative type

    DEFF Research Database (Denmark)

    Hjorth, Poul G.; Kokkendorff, Simon L.; Markvorsen, Steen

    2002-01-01

    We study finite metric spaces with elements picked from, and distances consistent with, ambient Riemannian manifolds. The concepts of negative type and strictly negative type are reviewed, and the conjecture that hyperbolic spaces are of strictly negative type is settled, in the affirmative...

  17. Extremely strict ideals in Banach spaces

    Indian Academy of Sciences (India)

    Abstract. Motivated by the notion of an ideal introduced by Godefroy et al. (Stu- dia Math. 104 (1993) 13–59), in this article, we introduce and study the notion of an extremely strict ideal. For a Poulsen simplex K, we show that the space of affine contin- uous functions on K is an extremely strict ideal in the space of continuous ...

  18. Finite Metric Spaces of Strictly negative Type

    DEFF Research Database (Denmark)

    Hjorth, Poul G.

    If a finite metric space is of strictly negative type then its transfinite diameter is uniquely realized by an infinite extent (“load vector''). Finite metric spaces that have this property include all trees, and all finite subspaces of Euclidean and Hyperbolic spaces. We prove that if the distance...... matrix of a finite metric space is both hypermetric and regular, then it is of strictly negative type. We show that the strictly negative type finite subspaces of spheres are precisely those which do not contain two pairs of antipodal points....

  19. Predicting sample size required for classification performance

    Directory of Open Access Journals (Sweden)

    Figueroa Rosa L

    2012-02-01

    Full Text Available Abstract Background Supervised learning methods need annotated data in order to generate efficient models. Annotated data, however, is a relatively scarce resource and can be expensive to obtain. For both passive and active learning methods, there is a need to estimate the size of the annotated sample required to reach a performance target. Methods We designed and implemented a method that fits an inverse power law model to points of a given learning curve created using a small annotated training set. Fitting is carried out using nonlinear weighted least squares optimization. The fitted model is then used to predict the classifier's performance and confidence interval for larger sample sizes. For evaluation, the nonlinear weighted curve fitting method was applied to a set of learning curves generated using clinical text and waveform classification tasks with active and passive sampling methods, and predictions were validated using standard goodness of fit measures. As control we used an un-weighted fitting method. Results A total of 568 models were fitted and the model predictions were compared with the observed performances. Depending on the data set and sampling method, it took between 80 to 560 annotated samples to achieve mean average and root mean squared error below 0.01. Results also show that our weighted fitting method outperformed the baseline un-weighted method (p Conclusions This paper describes a simple and effective sample size prediction algorithm that conducts weighted fitting of learning curves. The algorithm outperformed an un-weighted algorithm described in previous literature. It can help researchers determine annotation sample size for supervised machine learning.

  20. Hyperbolic spaces are of strictly negative type

    DEFF Research Database (Denmark)

    Hjorth, Poul G.; Kokkendorff, Simon L.; Markvorsen, Steen

    2002-01-01

    We study finite metric spaces with elements picked from, and distances consistent with, ambient Riemannian manifolds. The concepts of negative type and strictly negative type are reviewed, and the conjecture that hyperbolic spaces are of strictly negative type is settled, in the affirmative....... The technique of the proof is subsequently applied to show that every compact manifold of negative type must have trivial fundamental group, and to obtain a necessary criterion for product manifolds to be of negative type....

  1. Dosimeter characteristics and service performance requirements

    International Nuclear Information System (INIS)

    Ambrosi, P.; Bartlett, D.T.

    1999-01-01

    The requirements for personal dosimeters and dosimetry services given by ICRP 26, ICRP 35, ICRP 60 and ICRP 75 are summarised and compared with the requirements given in relevant international standards. Most standards could be made more relevant to actual workplace conditions. In some standards, the required tests of energy and angular dependence of the response are not sufficient, or requirements on overall uncertainty are lacking. (author)

  2. Towards performance requirements for structural connections

    NARCIS (Netherlands)

    Stark, J.W.B.

    1999-01-01

    There is a tendency in the Construction Industry to move from solution driven specifications towards performance specifications. Traditionally structural specifications including those for steel construction used to be mainly solution driven. In this paper the position of the draft European

  3. Strictly convex functions on complete Finsler manifolds

    Indian Academy of Sciences (India)

    ... Refresher Courses · Symposia · Live Streaming. Home; Journals; Proceedings – Mathematical Sciences; Volume 126; Issue 4. Strictly convex functions on complete Finsler manifolds. YOE ITOKAWA KATSUHIRO SHIOHAMA BANKTESHWAR TIWARI. Research Article Volume 126 Issue 4 October 2016 pp 623-627 ...

  4. Finite Metric Spaces of Strictly Negative Type

    DEFF Research Database (Denmark)

    Hjorth, Poul; Lisonek, P.; Markvorsen, Steen

    1998-01-01

    We prove that, if a finite metric space is of strictly negative type, then its transfinite diameter is uniquely realized by the infinite extender (load vector). Finite metric spaces that have this property include all spaces on two, three, or four points, all trees, and all finite subspaces of Eu...

  5. Cost optimal levels for energy performance requirements

    DEFF Research Database (Denmark)

    Thomsen, Kirsten Engelund; Aggerholm, Søren; Kluttig-Erhorn, Heike

    This report summarises the work done within the Concerted Action EPBD from December 2010 to April 2011 in order to feed into the European Commission's proposal for a common European procedure for a Cost-Optimal methodology under the Directive on the Energy Performance of Buildings (recast) 2010/3...

  6. Performance requirements for locomotive braking systems

    CSIR Research Space (South Africa)

    Vermaak, P

    2000-02-01

    Full Text Available that affect braking performance, or the distance within which a train can be stopped, include: • The speed of the train. • The driver’s reaction time. • Wet or muddy track. • Mechanical condition of the track. • Super-elevation or the lack of super-elevation...

  7. Extremely strict ideals in Banach spaces

    Indian Academy of Sciences (India)

    the space of regular Borel measures, it is easy to see that with respect to the projection μ → μ|(0, 1), M is an extremely strict ideal in C([0, 1]) but as the Lebesgue measure is non-atomic, M. ∗. 1 is not the norm closed ..... (Grenoble) 28 (1978) 35–65. [10] Rao T S S R K, On ideals in Banach spaces, Rocky Mountain J. Math.

  8. Strictness Analysis and Denotational Abstract Interpretation

    DEFF Research Database (Denmark)

    Nielson, Flemming

    1988-01-01

    there and this sufices to make the framework applicable to strictness analysis for the lambda-calculus. This shows the possibility of a general theory for the analysis of functional programs and it gives more insight into the relative precision of the various analyses. In particular it is shown that a collecting (static......A theory of abstract interpretation () is developed for a typed lambda-calculus. The typed lambda-calculus may be viewed as the ''static'' part of a two-level denotational metalanguage for which abstract interpretation was developed by ). The present development relaxes a condition imposed...

  9. 7 CFR 28.441 - Strict Middling Yellow Stained Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Yellow Stained Color. 28.441 Section... Strict Middling Yellow Stained Color. Strict Middling Yellow Stained Color is color which is deeper than that of Strict Middling Tinged Color. [57 FR 34498, Aug. 5, 1992] ...

  10. 7 CFR 28.412 - Strict Middling Light Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Light Spotted Color. 28.412 Section 28... Light Spotted Color. Strict Middling Light Spotted Color is color which in spot or color, or both, is between Strict Middling Color and Strict Middling Spotted Color. ...

  11. A performance requirements analysis of the SSC control system

    International Nuclear Information System (INIS)

    Hunt, S.M.; Low, K.

    1992-01-01

    This paper presents the results of analysis of the performance requirements of the Superconducting Super Collider Control System. We quantify the performance requirements of the system in terms of response time, throughput and reliability. We then examine the effect of distance and traffic patterns on control system performance and examine how these factors influence the implementation of the control network architecture and compare the proposed system against those criteria. (author)

  12. Engineered Barrier System performance requirements systems study report. Revision 02

    International Nuclear Information System (INIS)

    Balady, M.A.

    1997-01-01

    This study evaluates the current design concept for the Engineered Barrier System (EBS), in concert with the current understanding of the geologic setting to assess whether enhancements to the required performance of the EBS are necessary. The performance assessment calculations are performed by coupling the EBS with the geologic setting based on the models (some of which were updated for this study) and assumptions used for the 1995 Total System Performance Assessment (TSPA). The need for enhancements is determined by comparing the performance assessment results against the EBS related performance requirements. Subsystem quantitative performance requirements related to the EBS include the requirement to allow no more than 1% of the waste packages (WPs) to fail before 1,000 years after permanent closure of the repository, as well as a requirement to control the release rate of radionuclides from the EBS. The EBS performance enhancements considered included additional engineered components as well as evaluating additional performance available from existing design features but for which no performance credit is currently being taken

  13. Engineered Barrier System performance requirements systems study report. Revision 02

    Energy Technology Data Exchange (ETDEWEB)

    Balady, M.A.

    1997-01-14

    This study evaluates the current design concept for the Engineered Barrier System (EBS), in concert with the current understanding of the geologic setting to assess whether enhancements to the required performance of the EBS are necessary. The performance assessment calculations are performed by coupling the EBS with the geologic setting based on the models (some of which were updated for this study) and assumptions used for the 1995 Total System Performance Assessment (TSPA). The need for enhancements is determined by comparing the performance assessment results against the EBS related performance requirements. Subsystem quantitative performance requirements related to the EBS include the requirement to allow no more than 1% of the waste packages (WPs) to fail before 1,000 years after permanent closure of the repository, as well as a requirement to control the release rate of radionuclides from the EBS. The EBS performance enhancements considered included additional engineered components as well as evaluating additional performance available from existing design features but for which no performance credit is currently being taken.

  14. Performance requirements for integrated voice/data networks

    Science.gov (United States)

    Gruber, J. G.; Le, N. H.

    1983-12-01

    This paper addresses top-down end-to-end user-oriented performance requirements pertaining primarily to voice and digital data services. The discussion of requirements for voice parameters accounts for the performance of existing analog and mixed analog/digital networks, as well as the likely effects on performance of short, medium, and long term evolution toward the ultimate all digital ISDN. The requirements for digital data parameters necessarily reflect an evolutionary process which is less consistent than for voice, and therefore these requirements are less definitive in nature. The discussions of voice and digital data performance apply largely to a wide variety of appropriate network designs, transmission schemes, and switching architectures. Both traditional parameters, as well as contemporary parameters associated with new and evolving systems, are considered. The emphasis is on the performance of nation-wide public and private networks, but the paper also considers the constraints of international connections.

  15. The contribution of material control to meeting performance requirements

    International Nuclear Information System (INIS)

    Rivers, J.D.

    1989-01-01

    The U.S. Dept. of Energy (DOE) is in the process of implementing a set of performance requirements for material control and accountability (MC ampersand A). These graded requirements set a uniform level of performance for similar materials at various facilities with respect to the threat of an insider adversary stealing special nuclear material (SNM). These requirements are phrased in terms of detecting the theft of a goal quantity of SNM within a specified time period and with a probability greater than or equal to a specified value and include defense in-depth requirements

  16. Geometrical optimization for strictly localized structures

    Science.gov (United States)

    Mo, Yirong

    2003-07-01

    Recently we proposed the block localized wavefunction (BLW) approach which takes the advantages of valence bond theory and molecular orbital theory and defines the wavefunctions for resonance structures based on the assumption that all electrons and orbitals are partitioned into a few subgroups. In this work, we implement the geometrical optimization of the BLW method based on the algorithm proposed by Gianinetti and coworkers. Thus, we can study the conjugation effect on not only the molecular stability, but also the molecular geometry. With this capability, the π conjugation effect in trans-polyenes C2nH2n+2 (n=2-5) as well as in formamide and its analogs are studied by optimizing their delocalized and strictly localized forms with the 6-31G(d) and 6-311+G(d,p) basis sets. Although it has been well presumed that the π resonance shortens the single bonds and lengthens the double bonds with the delocalization of π electrons across the whole line in polyenes, our optimization of the strictly localized structures quantitatively shows that when the conjugation effect is "turned off," the double bond lengths will be identical to the CC bond length in ethylene and the single Csp2-Csp2 bond length will be about 1.513-1.517 Å. In agreement with the classical Hückel theory, the resonance energies in polyenes are approximately in proportion to the number of double bonds. Similarly, resonance is responsible not only for the planarity of formamide, thioformamide, and selenoformamide, but also for the lengthening of the CX (X=O,S,Se) double bond and the shortening of the CN bonds. Although it is assumed that the CX bond polarization decreases in the order of O>S>Se, the π electronic delocalization increases in the opposite order, i.e., formamide

  17. Ensemble Time in GNSS - Performance Requirements and Algorithm Tests

    National Research Council Canada - National Science Library

    Suess, Mattgias; Moudrak, Alexandre; Frolova, E

    2007-01-01

    Any Global Navigation Satellite System (GNSS) relies on a highly stable and reliable System Time that has to meet high-performance requirements to enable GNSS services suitable for navigation and timing communities...

  18. From Regular to Strictly Locally Testable Languages

    Directory of Open Access Journals (Sweden)

    Stefano Crespi Reghizzi

    2011-08-01

    Full Text Available A classical result (often credited to Y. Medvedev states that every language recognized by a finite automaton is the homomorphic image of a local language, over a much larger so-called local alphabet, namely the alphabet of the edges of the transition graph. Local languages are characterized by the value k=2 of the sliding window width in the McNaughton and Papert's infinite hierarchy of strictly locally testable languages (k-slt. We generalize Medvedev's result in a new direction, studying the relationship between the width and the alphabetic ratio telling how much larger the local alphabet is. We prove that every regular language is the image of a k-slt language on an alphabet of doubled size, where the width logarithmically depends on the automaton size, and we exhibit regular languages for which any smaller alphabetic ratio is insufficient. More generally, we express the trade-off between alphabetic ratio and width as a mathematical relation derived from a careful encoding of the states. At last we mention some directions for theoretical development and application.

  19. 7 CFR 28.404 - Strict Low Middling Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Low Middling Color. 28.404 Section 28.404... for the Color Grade of American Upland Cotton § 28.404 Strict Low Middling Color. Strict Low Middling Color is color which is within the range represented by a set of samples in the custody of the United...

  20. 7 CFR 28.406 - Strict Good Ordinary Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Good Ordinary Color. 28.406 Section 28.406... for the Color Grade of American Upland Cotton § 28.406 Strict Good Ordinary Color. Strict Good Ordinary Color is color which is within the range represented by a set of samples in the custody of the...

  1. 7 CFR 28.402 - Strict Middling Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Color. 28.402 Section 28.402... for the Color Grade of American Upland Cotton § 28.402 Strict Middling Color. Strict Middling Color is color which is within the range represented by a set of samples in the custody of the United States...

  2. Cost-optimal levels for energy performance requirements

    DEFF Research Database (Denmark)

    Thomsen, Kirsten Engelund; Aggerholm, Søren; Kluttig-Erhorn, Heike

    2011-01-01

    The CA conducted a study on experiences and challenges for setting cost optimal levels for energy performance requirements. The results were used as input by the EU Commission in their work of establishing the Regulation on a comparative methodology framework for calculating cost optimal levels...... of minimum energy performance requirements. In addition to the summary report released in August 2011, the full detailed report on this study is now also made available, just as the EC is about to publish its proposed Regulation for MS to apply in their process to update national building requirements....

  3. Input data required for specific performance assessment codes

    International Nuclear Information System (INIS)

    Seitz, R.R.; Garcia, R.S.; Starmer, R.J.; Dicke, C.A.; Leonard, P.R.; Maheras, S.J.; Rood, A.S.; Smith, R.W.

    1992-02-01

    The Department of Energy's National Low-Level Waste Management Program at the Idaho National Engineering Laboratory generated this report on input data requirements for computer codes to assist States and compacts in their performance assessments. This report gives generators, developers, operators, and users some guidelines on what input data is required to satisfy 22 common performance assessment codes. Each of the codes is summarized and a matrix table is provided to allow comparison of the various input required by the codes. This report does not determine or recommend which codes are preferable

  4. Mammalian evolution may not be strictly bifurcating.

    Science.gov (United States)

    Hallström, Björn M; Janke, Axel

    2010-12-01

    The massive amount of genomic sequence data that is now available for analyzing evolutionary relationships among 31 placental mammals reduces the stochastic error in phylogenetic analyses to virtually zero. One would expect that this would make it possible to finally resolve controversial branches in the placental mammalian tree. We analyzed a 2,863,797 nucleotide-long alignment (3,364 genes) from 31 placental mammals for reconstructing their evolution. Most placental mammalian relationships were resolved, and a consensus of their evolution is emerging. However, certain branches remain difficult or virtually impossible to resolve. These branches are characterized by short divergence times in the order of 1-4 million years. Computer simulations based on parameters from the real data show that as little as about 12,500 amino acid sites could be sufficient to confidently resolve short branches as old as about 90 million years ago (Ma). Thus, the amount of sequence data should no longer be a limiting factor in resolving the relationships among placental mammals. The timing of the early radiation of placental mammals coincides with a period of climate warming some 100-80 Ma and with continental fragmentation. These global processes may have triggered the rapid diversification of placental mammals. However, the rapid radiations of certain mammalian groups complicate phylogenetic analyses, possibly due to incomplete lineage sorting and introgression. These speciation-related processes led to a mosaic genome and conflicting phylogenetic signals. Split network methods are ideal for visualizing these problematic branches and can therefore depict data conflict and possibly the true evolutionary history better than strictly bifurcating trees. Given the timing of tectonics, of placental mammalian divergences, and the fossil record, a Laurasian rather than Gondwanan origin of placental mammals seems the most parsimonious explanation.

  5. Assessment of Performance-based Requirements for Structural Design

    DEFF Research Database (Denmark)

    Hertz, Kristian Dahl

    2005-01-01

    The paper presents how actions can be assessed for a performance-based structural fire safety design from the first formulations in the building program to the final derivations of the fire load to be applied for each structural member. In order to indicate what is of importance for the assessment...... of the requirements, a couple of simple analyses of structural response are made. The examples are chosen deliberately to show the difference between a traditional design based on standard fire resistance and a performance-based approach. A methodology is developed for a decision on the safety level...... and for a detailed assessment of the requirements. The design requirements to be used for a factory producing elements for industrial housing for unknown costumers are discussed, and a fully developed fire is recommended as a common requirement for domestic houses, hotels, offices, schools and hospitals. In addition...

  6. 42 CFR 84.103 - Man tests; performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Man tests; performance requirements. 84.103 Section 84.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.103 Man tests;...

  7. 14 CFR 171.259 - Performance requirements: General.

    Science.gov (United States)

    2010-01-01

    ... System (ISMLS) § 171.259 Performance requirements: General. (a) The ISMLS consists of the following basic... purposes, the tolerances given in parentheses indicated by an asterisk apply to the test instruments used to measure these parameters. Elevation, 0 to 10,000 ft. above sea level. Duty, continuous, unattended...

  8. 42 CFR 84.1156 - Pesticide respirators; performance requirements; general.

    Science.gov (United States)

    2010-10-01

    ... DEVICES Dust, Fume, and Mist; Pesticide; Paint Spray; Powered Air-Purifying High Efficiency Respirators and Combination Gas Masks § 84.1156 Pesticide respirators; performance requirements; general... gas mask 70 85 20 Chin-style gas mask 65 80 20 Powered air-purifying 2 2 50 2 70 20 Chemical Cartridge...

  9. High performance sealing - meeting nuclear and aerospace requirements

    International Nuclear Information System (INIS)

    Wensel, R.; Metcalfe, R.

    1994-11-01

    Although high performance sealing is required in many places, two industries lead all others in terms of their demand-nuclear and aerospace. The factors that govern the high reliability and integrity of seals, particularly elastomer seals, for both industries are discussed. Aerospace requirements include low structural weight and a broad range of conditions, from the cold vacuum of space to the hot, high pressures of rocket motors. It is shown, by example, how a seal can be made an integral part of a structure in order to improve performance, rather than using a conventional handbook design. Typical processes are then described for selection, specification and procurement of suitable elastomers, functional and accelerated performance testing, database development and service-life prediction. Methods for quality assurance of elastomer seals are summarized. Potentially catastrophic internal dejects are a particular problem for conventional non-destructive inspection techniques. A new method of elastodynamic testing for these is described. (author)

  10. Required performance to the concrete structure of the accelerator facilities

    International Nuclear Information System (INIS)

    Irie, Masaaki; Yoshioka, Masakazu; Miyahara, Masanobu

    2006-01-01

    As for the accelerator facility, there is many a thing which is constructed as underground concrete structure from viewpoint such as cover of radiation and stability of the structure. Required performance to the concrete structure of the accelerator facility is the same as the general social infrastructure, but it has been possessed the feature where target performance differs largely. As for the body sentence, expressing the difference of the performance which is required from the concrete structure of the social infrastructure and the accelerator facility, construction management of the concrete structure which it plans from order of the accelerator engineering works facility, reaches to the design, supervision and operation it is something which expresses the method of thinking. In addition, in the future of material structural analysis of the concrete which uses the neutron accelerator concerning view it showed. (author)

  11. Performance Requirements on Remodeling Apartment Housing and TOPSIS Evaluation

    Directory of Open Access Journals (Sweden)

    Jaeho Cho

    2015-01-01

    Full Text Available Functional improvement needed in remodeling projects is determined by users in a complex manner since remodeling projects require performance improvement against deterioration. This study defines fundamental Remodeling Performance Criteria (RPC for apartment housing by referring to performance criteria of both domestic and international performance-related systems. In this case study, performance evaluation of Construction Element Method (CEM for remodeling projects was conducted based on RPC. For the objective evaluation of CEM, performance scores were calculated and normalized by using the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS model, which is used in a multicriteria decision-making method. The TOPSIS evaluation model allows for a comprehensive and comparative analysis on the performance of the remodeling solution. The TOPSIS model in this study suggests a standard logic of performance evaluation for aged buildings as it analyzes the degree of deterioration at the prior remodeling phase and predicts the performance improvement level for CEM at the remodeling planning phase.

  12. Performance Evaluation and Requirements Assessment for Gravity Gradient Referenced Navigation

    Directory of Open Access Journals (Sweden)

    Jisun Lee

    2015-07-01

    Full Text Available In this study, simulation tests for gravity gradient referenced navigation (GGRN are conducted to verify the effects of various factors such as database (DB and sensor errors, flight altitude, DB resolution, initial errors, and measurement update rates on the navigation performance. Based on the simulation results, requirements for GGRN are established for position determination with certain target accuracies. It is found that DB and sensor errors and flight altitude have strong effects on the navigation performance. In particular, a DB and sensor with accuracies of 0.1 E and 0.01 E, respectively, are required to determine the position more accurately than or at a level similar to the navigation performance of terrain referenced navigation (TRN. In most cases, the horizontal position error of GGRN is less than 100 m. However, the navigation performance of GGRN is similar to or worse than that of a pure inertial navigation system when the DB and sensor errors are 3 E or 5 E each and the flight altitude is 3000 m. Considering that the accuracy of currently available gradiometers is about 3 E or 5 E, GGRN does not show much advantage over TRN at present. However, GGRN is expected to exhibit much better performance in the near future when accurate DBs and gravity gradiometer are available.

  13. ASC-ATDM Performance Portability Requirements for 2015-2019

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, Harold C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Computing Research Center; Trott, Christian Robert [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Computing Research Center

    2015-03-01

    This report outlines the research, development, and support requirements for the Advanced Simulation and Computing (ASC ) Advanced Technology, Development, and Mitigation (ATDM) Performance Portability (a.k.a., Kokkos) project for 2015 - 2019 . The research and development (R&D) goal for Kokkos (v2) has been to create and demonstrate a thread - parallel programming model a nd standard C++ library - based implementation that enables performance portability across diverse manycore architectures such as multicore CPU, Intel Xeon Phi, and NVIDIA Kepler GPU. This R&D goal has been achieved for algorithms that use data parallel pat terns including parallel - for, parallel - reduce, and parallel - scan. Current R&D is focusing on hierarchical parallel patterns such as a directed acyclic graph (DAG) of asynchronous tasks where each task contain s nested data parallel algorithms. This five y ear plan includes R&D required to f ully and performance portably exploit thread parallelism across current and anticipated next generation platforms (NGP). The Kokkos library is being evaluated by many projects exploring algorithm s and code design for NGP. Some production libraries and applications such as Trilinos and LAMMPS have already committed to Kokkos as their foundation for manycore parallelism an d performance portability. These five year requirements includes support required for current and antic ipated ASC projects to be effective and productive in their use of Kokkos on NGP. The greatest risk to the success of Kokkos and ASC projects relying upon Kokkos is a lack of staffing resources to support Kokkos to the degree needed by these ASC projects. This support includes up - to - date tutorials, documentation, multi - platform (hardware and software stack) testing, minor feature enhancements, thread - scalable algorithm consulting, and managing collaborative R&D.

  14. Modal Inclusion Logic: Being Lax is Simpler than Being Strict

    DEFF Research Database (Denmark)

    Hella, Lauri; Kuusisto, Antti Johannes; Meier, Arne

    2015-01-01

    We investigate the computational complexity of the satisfiability problem of modal inclusion logic. We distinguish two variants of the problem: one for strict and another one for lax semantics. The complexity of the lax version turns out to be complete for EXPTIME, whereas with strict semantics...

  15. 7 CFR 28.431 - Strict Middling Tinged Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Tinged Color. 28.431 Section 28.431 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Color. Strict Middling Tinged Color is color which is better than Middling Tinged Color. ...

  16. 7 CFR 28.433 - Strict Low Middling Tinged Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Low Middling Tinged Color. 28.433 Section 28.433 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Tinged Color. Strict Low Middling Tinged Color is color which is within the range represented by a set of...

  17. 7 CFR 28.424 - Strict Low Middling Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Low Middling Spotted Color. 28.424 Section 28.424 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Spotted Color. Strict Low Middling Spotted Color is color which is within the range represented by a set...

  18. 7 CFR 28.426 - Strict Good Ordinary Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Good Ordinary Spotted Color. 28.426 Section 28.426 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Spotted Color. Strict Good Ordinary Spotted Color is color which is within the range represented by a set...

  19. 7 CFR 28.422 - Strict Middling Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Spotted Color. 28.422 Section 28.422 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Color. Strict Middling Spotted Color is color which is within the range represented by a set of samples...

  20. Strictly-regular number system and data structures

    DEFF Research Database (Denmark)

    Elmasry, Amr Ahmed Abd Elmoneim; Jensen, Claus; Katajainen, Jyrki

    2010-01-01

    We introduce a new number system that we call the strictly-regular system, which efficiently supports the operations: digit-increment, digit-decrement, cut, concatenate, and add. Compared to other number systems, the strictly-regular system has distinguishable properties. It is superior to the re...

  1. Performance and design requirements for a graphics display research facility

    International Nuclear Information System (INIS)

    Tillitt, D.N.; Petersen, R.J.; Smith, R.L.

    1982-06-01

    Performance and design requirements for a Graphics Display Research Facility (GDRF) are presented. The GDRF is an evolutionary, computer-based, human-engineering experimentation center that is specifically designed to address long-term research issues associated with automation, human performance, and risk in the operation of nuclear facilities. Research capabilities provided by this facility will directly support the licensing and regulation of nuclear facilities within the United States. Research provided by this facility is intended to satisfy the Nuclear Regulatory Commission's (NRC) needs to: (a) confirm design adequacy of, and develop evaluation criteria for, computerized graphic displays and other information presentation mechanisms proposed for use in nuclear power plants, and (b) assess the possible effects on operator performance of computer-based operator-support concepts. The ultimate goal of this research is to support regulatory directives for minimizing the risk of human error in the operation of nuclear facilities

  2. Are strict vegetarians protected against prostate cancer?

    Science.gov (United States)

    Tantamango-Bartley, Yessenia; Knutsen, Synnove F; Knutsen, Raymond; Jacobsen, Bjarne K; Fan, Jing; Beeson, W Lawrence; Sabate, Joan; Hadley, David; Jaceldo-Siegl, Karen; Penniecook, Jason; Herring, Patti; Butler, Terry; Bennett, Hanni; Fraser, Gary

    2016-01-01

    According to the American Cancer Society, prostate cancer accounts for ∼27% of all incident cancer cases among men and is the second most common (noncutaneous) cancer among men. The relation between diet and prostate cancer is still unclear. Because people do not consume individual foods but rather foods in combination, the assessment of dietary patterns may offer valuable information when determining associations between diet and prostate cancer risk. This study aimed to examine the association between dietary patterns (nonvegetarian, lacto-ovo-vegetarian, pesco-vegetarian, vegan, and semi-vegetarian) and prostate cancer incidence among 26,346 male participants of the Adventist Health Study-2. In this prospective cohort study, cancer cases were identified by matching to cancer registries. Cox proportional hazards regression analysis was performed to estimate HRs by using age as the time variable. In total, 1079 incident prostate cancer cases were identified. Around 8% of the study population reported adherence to the vegan diet. Vegan diets showed a statistically significant protective association with prostate cancer risk (HR: 0.65; 95% CI: 0.49, 0.85). After stratifying by race, the statistically significant association with a vegan diet remained only for the whites (HR: 0.63; 95% CI: 0.46, 0.86), but the multivariate HR for black vegans showed a similar but nonsignificant point estimate (HR: 0.69; 95% CI: 0.41, 1.18). Vegan diets may confer a lower risk of prostate cancer. This lower estimated risk is seen in both white and black vegan subjects, although in the latter, the CI is wider and includes the null. © 2016 American Society for Nutrition.

  3. Design requirements and performance requirements for reactor fuel recycle manipulator systems

    International Nuclear Information System (INIS)

    Grundmann, J.G.

    1975-01-01

    The development of a new generation of remote handling devices for remote production work in support of reactor fuel recycle systems is discussed. These devices require greater mobility, speed and visual capability than remote handling systems used in research activities. An upgraded manipulator system proposed for a High-Temperature Gas-Cooled Reactor fuel refabrication facility is described. Design and performance criteria for the manipulators, cranes, and TV cameras in the proposed system are enumerated

  4. Turboelectric Aircraft Drive Key Performance Parameters and Functional Requirements

    Science.gov (United States)

    Jansen, Ralph H.; Brown, Gerald V.; Felder, James L.; Duffy, Kirsten P.

    2016-01-01

    The purpose of this paper is to propose specific power and efficiency as the key performance parameters for a turboelectric aircraft power system and investigate their impact on the overall aircraft. Key functional requirements are identified that impact the power system design. Breguet range equations for a base aircraft and a turboelectric aircraft are found. The benefits and costs that may result from the turboelectric system are enumerated. A break-even analysis is conducted to find the minimum allowable electric drive specific power and efficiency that can preserve the range, initial weight, operating empty weight, and payload weight of the base aircraft.

  5. Optical performance requirements for MEMS-scanner-based microdisplays

    Science.gov (United States)

    Urey, Hakan; Wine, David W.; Osborn, Thor D.

    2000-08-01

    High-resolution and high frame rate dynamic microdisplays can be implemented by scanning a photon beam in a raster format across the viewer's retina. Microvision is developing biaxial MEMS scanners for such video display applications. This paper discusses the optical performance requirements for scanning display systems. The display resolution directly translates into a scan-angle-mirror-size product and the frame rate translates into vertical and horizontal scanner frequencies. (theta) -product and fh are both very important figures of merit for scanner performance comparison. In addition, the static and dynamic flatness of the scanners, off-axis motion and scan repeatability, scanner position sensor accuracy all have a direct impact on display image quality.

  6. Strategy and Aspects of Monitoring / Control Strictly in Coordinated Subsystems

    Directory of Open Access Journals (Sweden)

    William José Borges

    2012-06-01

    Full Text Available This paper aims to discuss the approach structures of the strictly coordinated theoretical framework developed by Zylbersztajn and Farina (1999 as an expanded perspective of the firm, taking into account the food supply chains as an extension of the nexus of contracts proposed by Coase (1937 and taken up by Williamson (1985. The structures stand out as strictly coordinated. Zylbersztajn and Farina (1999 turn to identifying points of common interests that encourage firms to promote contracts between themselves in a strictly coordinated way, considering the degree of asset specificity involved in the transaction and the competitive forces that determine the search for strategic positioning organizations to achieve sustainable superior results.

  7. Managing Hanford Site solid waste through strict acceptance criteria

    International Nuclear Information System (INIS)

    Jasen, W.G.; Pierce, R.D.; Willis, N.P.

    1993-02-01

    Various types of waste have been generated during the 50-year history of the Hanford Site. Regulatory changes in the last 20 years have provided the emphasis for better management of these wastes. Interpretations of the Atomic Energy Act of 1954 (AEA) and the Resource Conservation and Recovery Act of 1976 (RCRA) have led to the definition of a group of wastes called radioactive mixed wastes (RMW). As a result of the radioactive and hazardous properties of these wastes, strict management programs have been implemented for the management of these wastes. Solid waste management is accomplished through a systems performance approach to waste management that used best-demonstrated available technology (BDAT) and best management practices. The solid waste program at the Hanford Site strives to integrate all aspects of management relative to the treatment, storage and disposal (TSD) of solid waste. Often there are many competing and important needs. It is a difficult task to balance these needs in a manner that is both equitable and productive. Management science is used to help the process of making decisions. Tools used to support the decision making process include five-year planning, cost estimating, resource allocation, performance assessment, waste volume forecasts, input/output models, and waste acceptance criteria. The purpose of this document is to describe how one of these tools, waste acceptance criteria, has helped the Hanford Site manage solid wastes

  8. An Approach for Performance Based Glove Mobility Requirements

    Science.gov (United States)

    Aitchison, Lindsay; Benson, Elizabeth; England, Scott

    2016-01-01

    The Space Suit Assembly (SSA) Development Team at NASA Johnson Space Center has invested heavily in the advancement of rear-entry planetary exploration suit design but largely deferred development of extravehicular activity (EVA) glove designs, and accepted the risk of using the current flight gloves, Phase VI, for exploration missions. However, as design reference missions mature, the risks of using heritage hardware have highlighted the need for developing robust new glove technologies. To address the technology gap, the NASA Space Technology Mission Directorate's Game-Changing Development Program provided start-up funding for the High Performance EVA Glove (HPEG) Element as part of the Next Generation Life Support (NGLS) Project in the fall of 2013. The overarching goal of the HPEG Element is to develop a robust glove design that increases human performance during EVA and creates pathway for implementation of emergent technologies, with specific aims of increasing pressurized mobility to 60% of barehanded capability, increasing the durability in on-pristine environments, and decreasing the potential of gloves to cause injury during use. The HPEG Element focused initial efforts on developing quantifiable and repeatable methodologies for assessing glove performance with respect to mobility, injury potential, thermal conductivity, and abrasion resistance. The team used these methodologies to establish requirements against which emerging technologies and glove designs can be assessed at both the component and assembly levels. The mobility performance testing methodology was an early focus for the HPEG team as it stems from collaborations between the SSA Development team and the JSC Anthropometry and Biomechanics Facility (ABF) that began investigating new methods for suited mobility and fit early in the Constellation Program. The combined HPEG and ABF team used lessons learned from the previous efforts as well as additional reviews of methodologies in physical and

  9. Strict finitism and the logic of mathematical applications

    CERN Document Server

    Ye, Feng

    2011-01-01

    Exploring the logic behind applied mathematics to the physical world, this volume illustrates how radical naturalism, nominalism and strict finitism can account for the applications of classical mathematics in current theories about natural phenomena.

  10. Strict monotonicity and unique continuation of the biharmonic operator

    Directory of Open Access Journals (Sweden)

    Najib Tsouli

    2012-01-01

    Full Text Available In this paper, we will show that the strict monotonicity of the eigenvalues of the biharmonic operator holds if and only if some unique continuation property is satisfied by the corresponding eigenfunctions.

  11. Two examples of non strictly convex large deviations

    OpenAIRE

    De Marco, Stefano; Jacquier, Antoine; Roome, Patrick

    2016-01-01

    We present two examples of a large deviations principle where the rate function is not strictly convex. This is motivated by a model used in mathematical finance (the Heston model), and adds a new item to the zoology of non strictly convex large deviations. For one of these examples, we show that the rate function of the Cramer-type of large deviations coincides with that of the Freidlin-Wentzell when contraction principles are applied.

  12. Strictly contractive quantum channels and physically realizable quantum computers

    International Nuclear Information System (INIS)

    Raginsky, Maxim

    2002-01-01

    We study the robustness of quantum computers under the influence of errors modeled by strictly contractive channels. A channel T is defined to be strictly contractive if, for any pair of density operators ρ, σ in its domain, parallel Tρ-Tσ parallel 1 ≤k parallel ρ-σ parallel 1 for some 0≤k 1 denotes the trace norm). In other words, strictly contractive channels render the states of the computer less distinguishable in the sense of quantum detection theory. Starting from the premise that all experimental procedures can be carried out with finite precision, we argue that there exists a physically meaningful connection between strictly contractive channels and errors in physically realizable quantum computers. We show that, in the absence of error correction, sensitivity of quantum memories and computers to strictly contractive errors grows exponentially with storage time and computation time, respectively, and depends only on the constant k and the measurement precision. We prove that strict contractivity rules out the possibility of perfect error correction, and give an argument that approximate error correction, which covers previous work on fault-tolerant quantum computation as a special case, is possible

  13. Convergence theorems for strictly hemi-contractive maps

    International Nuclear Information System (INIS)

    Chidume, C.E.; Osilike, M.O.

    1992-04-01

    It is proved that each of two well-known fixed point iteration methods (the Mann and the Ishikawa iteration methods) converges strongly to the fixed point of strictly hemi-contractive map in real Banach spaces with property (U, λ, m+1,m), λ is an element of R, m is an element of IN. The class of strictly hemi-contractive maps includes all strictly pseudo-contractive maps with nonempty fixed point sets; and Banach spaces with property (U, λ, m+1, m), λ is an element of R, m is an element of IN include the L p (or l p ) spaces, p≥2. Our theorems generalize important known results. (author). 22 refs

  14. Assessment of Performance-based Requirements for Structural Design

    DEFF Research Database (Denmark)

    Hertz, Kristian Dahl

    2005-01-01

    and for a detailed assessment of the requirements. The design requirements to be used for a factory producing elements for industrial housing for unknown costumers are discussed, and a fully developed fire is recommended as a common requirement for domestic houses, hotels, offices, schools and hospitals. In addition...

  15. Evaluation of the Trade Space Between UAS Maneuver Performance and SAA System Performance Requirements

    Science.gov (United States)

    Jack, Devin P.; Hoffler, Keith D.; Johnson, Sally C.

    2014-01-01

    A need exists to safely integrate Unmanned Aircraft Systems (UAS) into the National Airspace System. Replacing manned aircraft's see-and-avoid capability in the absence of an onboard pilot is one of the key challenges associated with safe integration. Sense-and-avoid (SAA) systems will have to achieve yet-to-be-determined required separation distances for a wide range of encounters. They will also need to account for the maneuver performance of the UAS they are paired with. The work described in this paper is aimed at developing an understanding of the trade space between UAS maneuver performance and SAA system performance requirements. An assessment of current manned and unmanned aircraft performance was used to establish potential UAS performance test matrix bounds. Then, nearterm UAS integration work was used to narrow down the scope. A simulator was developed with sufficient fidelity to assess SAA system performance requirements for a wide range of encounters. The simulator generates closest-point-of-approach (CPA) data from the wide range of UAS performance models maneuvering against a single intruder with various encounter geometries. The simulator is described herein and has both a graphical user interface and batch interface to support detailed analysis of individual UAS encounters and macro analysis of a very large set of UAS and encounter models, respectively. Results from the simulator using approximate performance data from a well-known manned aircraft is presented to provide insight into the problem and as verification and validation of the simulator. Analysis of climb, descent, and level turn maneuvers to avoid a collision is presented. Noting the diversity of backgrounds in the UAS community, a description of the UAS aerodynamic and propulsive design and performance parameters is included. Initial attempts to model the results made it clear that developing maneuver performance groups is required. Discussion of the performance groups developed and how

  16. Mann iteration with errors for strictly pseudo-contractive mappings ...

    African Journals Online (AJOL)

    It is well known that any fixed point of a Lipschitzian strictly pseudo-contractive self mapping of a nonempty closed convex and bounded subset K of a Banach space X is unique [6] and may be norm approximated by an iterative procedure. In this paper, we show that Mann iteration with errors can be used to approximate the ...

  17. Dominated operators, absolutely summing operators and the strict ...

    African Journals Online (AJOL)

    b(X;E) be the space of all E-valued bounded continuous functions on X, equipped with the strict topology β. We study dominated and absolutely summing operators T : Cb(X;E) → F. We derive that if X is a locally compact Hausdorff space and E ...

  18. Convergence of GAOR Iterative Method with Strictly Diagonally Dominant Matrices

    Directory of Open Access Journals (Sweden)

    Guangbin Wang

    2011-01-01

    Full Text Available We discuss the convergence of GAOR method for linear systems with strictly diagonally dominant matrices. Moreover, we show that our results are better than ones of Darvishi and Hessari (2006, Tian et al. (2008 by using three numerical examples.

  19. Runaway selection for cooperation and strict-and-severe punishment.

    Science.gov (United States)

    Nakamaru, Mayuko; Dieckmann, Ulf

    2009-03-07

    Punishing defectors is an important means of stabilizing cooperation. When levels of cooperation and punishment are continuous, individuals must employ suitable social standards for defining defectors and for determining punishment levels. Here we investigate the evolution of a social reaction norm, or psychological response function, for determining the punishment level meted out by individuals in dependence on the cooperation level exhibited by their neighbors in a lattice-structured population. We find that (1) cooperation and punishment can undergo runaway selection, with evolution towards enhanced cooperation and an ever more demanding punishment reaction norm mutually reinforcing each other; (2) this mechanism works best when punishment is strict, so that ambiguities in defining defectors are small; (3) when the strictness of punishment can adapt jointly with the threshold and severity of punishment, evolution favors the strict-and-severe punishment of individuals who offer slightly less than average cooperation levels; (4) strict-and-severe punishment naturally evolves and leads to much enhanced cooperation when cooperation without punishment would be weak and neither cooperation nor punishment are too costly; and (5) such evolutionary dynamics enable the bootstrapping of cooperation and punishment, through which defectors who never punish gradually and steadily evolve into cooperators who punish those they define as defectors.

  20. Dominance on Strict Triangular Norms and Mulholland Inequality

    Czech Academy of Sciences Publication Activity Database

    Petrík, Milan

    2018-01-01

    Roč. 335, 15 March (2018), s. 3-17 ISSN 0165-0114 R&D Projects: GA ČR GJ15-07724Y Institutional support: RVO:67985807 Keywords : dominance relation * Mulholland inequality * strict triangular norm * transitivity Subject RIV: BA - General Mathematics Impact factor: 2.718, year: 2016

  1. Optimizing cementious content in concrete mixtures for required performance.

    Science.gov (United States)

    2012-01-01

    "This research investigated the effects of changing the cementitious content required at a given water-to-cement ratio (w/c) on workability, strength, and durability of a concrete mixture. : An experimental program was conducted in which 64 concrete ...

  2. EFSUMB Minimum Training Requirements for Rheumatologists Performing Musculoskeletal Ultrasound

    DEFF Research Database (Denmark)

    Terslev, L; Hammer, H B; Torp-Pedersen, S

    2013-01-01

    In order to optimize and standardize musculoskeletal ultrasonography education for rheumatologists, there is a need for competency assessments addressing the required training and practical and theoretical skills. This paper describes how these competency assessments for rheumatologists were deve...

  3. Musical Performances in Library: Is a License from ASCAP Required?

    Science.gov (United States)

    Wynbrandt, Robert A.

    1990-01-01

    Prepared at the request of the American Library Association by its attorneys, this article discusses federal copyright law as it pertains to musical performances in libraries. Guidelines are presented for determining whether a license from the American Society of Composers, Authors, and Publishers (ASCAP) or any other performing rights…

  4. 10 CFR 63.114 - Requirements for performance assessment.

    Science.gov (United States)

    2010-01-01

    ... processes of engineered barriers in the performance assessment, including those processes that would adversely affect the performance of natural barriers. Degradation, deterioration, or alteration processes of... surrounding region to the extent necessary, and information on the design of the engineered barrier system...

  5. Student Performance Requirements: Minitary Service. Continuation Education System Development Project.

    Science.gov (United States)

    La Puente Union High School District, CA.

    Funded under Title III of the Elementary and Secondary Education Act of 1965, the La Puente, California, continuation education project investigated (1) attitudes of former students concerning the success of the school in preparing them for entry into military service, (2) the minimal skills and knowledge required by each of the armed forces, (3)…

  6. Energy performance requirements using the cost-optimal methodology

    DEFF Research Database (Denmark)

    Wittchen, Kim Bjarne; Thomsen, Kirsten Engelund

    2013-01-01

    The Concerted Action EPBD (CA EPBD) has the main objective of assisting the EU Member States (MS) transpose and implement the recast Directive 2010/31/EU on the Energy Performance of Buildings (EPBD), published on 19 May 2010, as well as the continued implementation of the actions initiated with ...

  7. Performance Requirements Modeling andAssessment for Active Power Ancillary Services

    DEFF Research Database (Denmark)

    Bondy, Daniel Esteban Morales; Thavlov, Anders; Tougaard, Janus Bundsgaard Mosbæk

    2017-01-01

    system operation, a reliable service delivery is required, yet it may not be appropriate to apply conventional performance requirements to new technologies and methods. The service performance requirements and assessment methods therefore need to be generalized and standardized in order to include future...... ancillary service sources. This paper develops a modeling method for ancillary services performance requirements, including performance and verification indices. The use of the modeling method and the indices is exemplified in two case studies....

  8. ITER-EDA physics design requirements and plasma performance assessments

    International Nuclear Information System (INIS)

    Uckan, N.A.; Galambos, J.; Wesley, J.; Boucher, D.; Perkins, F.; Post, D.; Putvinski, S.

    1996-01-01

    Physics design guidelines, plasma performance estimates, and sensitivity of performance to changes in physics assumptions are presented for the ITER-EDA Interim Design. The overall ITER device parameters have been derived from the performance goals using physics guidelines based on the physics R ampersand D results. The ITER-EDA design has a single-null divertor configuration (divertor at the bottom) with a nominal plasma current of 21 MA, magnetic field of 5.68 T, major and minor radius of 8.14 m and 2.8 m, and a plasma elongation (at the 95% flux surface) of ∼1.6 that produces a nominal fusion power of ∼1.5 GW for an ignited burn pulse length of ≥1000 s. The assessments have shown that ignition at 1.5 GW of fusion power can be sustained in ITER for 1000 s given present extrapolations of H-mode confinement (τ E = 0.85 x τ ITER93H ), helium exhaust (τ* He /τ E = 10), representative plasma impurities (n Be /n e = 2%), and beta limit [β N = β(%)/(I/aB) ≤ 2.5]. The provision of 100 MW of auxiliary power, necessary to access to H-mode during the approach to ignition, provides for the possibility of driven burn operations at Q = 15. This enables ITER to fulfill its mission of fusion power (∼ 1--1.5 GW) and fluence (∼1 MWa/m 2 ) goals if confinement, impurity levels, or operational (density, beta) limits prove to be less favorable than present projections. The power threshold for H-L transition, confinement uncertainties, and operational limits (Greenwald density limit and beta limit) are potential performance limiting issues. Improvement of the helium exhaust (τ* He /τ E ≤ 5) and potential operation in reverse-shear mode significantly improve ITER performance

  9. Development of DSRC device and communication system performance measures recommendations for DSRC OBE performance and security requirements.

    Science.gov (United States)

    2016-05-22

    This report presents recommendations for minimum DSRC device communication performance and security : requirements to ensure effective operation of the DSRC system. The team identified recommended DSRC : communications requirements aligned to use cas...

  10. Operational requirements of spherical HTR fuel elements and their performance

    International Nuclear Information System (INIS)

    Roellig, K.; Theymann, W.

    1985-01-01

    The German development of spherical fuel elements with coated fuel particles led to a product design which fulfils the operational requirements for all HTR applications with mean gas exit temperatures from 700 deg C (electricity and steam generation) up to 950 deg C (supply of nuclear process heat). In spite of this relatively wide span for a parameter with strong impact on fuel element behaviour, almost identical fuel specifications can be used for the different reactor purposes. For pebble bed reactors with relatively low gas exit temperatures of 700 deg C, the ample design margins of the fuel elements offer the possibility to enlarge the scope of their in-service duties and, simultaneously, to improve fuel cycle economics. This is demonstrated for the HTR-500, an electricity and steam generating 500 MWel eq plant presently proposed as follow-up project to the THTR-300. Due to the low operating temperatures of the HTR-500 core, the fuel can be concentrated in about 70% of the pebbles of the core thus saving fuel cycle costs. Under all design accident conditions fuel temperatures are maintained below 1250 deg C. This allows a significant reduction in the engineered activity barriers outside the primary circuit, in particular for the loss of coolant accident. Furthermore, access to major primary circuit components and the reuse of the fuel elements after any design accident are possible. (author)

  11. A Hybrid P2P Overlay Network for Non-strictly Hierarchically Categorized Content

    Science.gov (United States)

    Wan, Yi; Asaka, Takuya; Takahashi, Tatsuro

    In P2P content distribution systems, there are many cases in which the content can be classified into hierarchically organized categories. In this paper, we propose a hybrid overlay network design suitable for such content called Pastry/NSHCC (Pastry for Non-Strictly Hierarchically Categorized Content). The semantic information of classification hierarchies of the content can be utilized regardless of whether they are in a strict tree structure or not. By doing so, the search scope can be restrained to any granularity, and the number of query messages also decreases while maintaining keyword searching availability. Through simulation, we showed that the proposed method provides better performance and lower overhead than unstructured overlays exploiting the same semantic information.

  12. Strict Criteria for Selection of Laparoscopy for Women with Adnexal Mass

    Science.gov (United States)

    Sallum, Luis Felipe; Sarian, Luis Otávio; Bastos, Joana Fróes Bragança; Derchain, Sophie

    2014-01-01

    Objectives: We compared the indication of laparoscopy for treatment of adnexal masses based on the risk scores and tumor diameters with the indication based on gynecology-oncologists' experience. Methods: This was a prospective study of 174 women who underwent surgery for adnexal tumors (116 laparotomies, 58 laparoscopies). The surgeries begun and completed by laparoscopy, with benign pathologic diagnosis, were considered successful. Laparoscopic surgeries that required conversion to laparotomy, led to a malignant diagnosis, or facilitated cyst rupture were considered failures. Two groups were defined for laparoscopy indication: (1) absence of American College of Obstetrics and Gynecology (ACOG) guideline for referral of high-risk adnexal masses criteria (ACOG negative) associated with 3 different tumor sizes (10, 12, and 14 cm); and (2) Index of Risk of Malignancy (IRM) with cutoffs at 100, 200, and 300, associated with the same 3 tumor sizes. Both groups were compared with the indication based on the surgeon's experience to verify whether the selection based on strict rules would improve the rate of successful laparoscopy. Results: ACOG-negative and tumors ≤10 cm and IRM with a cutoff at 300 points and tumors ≤10cm resulted in the same best performance (78% success = 38/49 laparoscopies). However, compared with the results of the gynecology-oncologists' experience, those were not statistically significant. Discussion: The selection of patients with adnexal mass to laparoscopy by the use of the ACOG guideline or IRM associated with tumor diameter had similar performance as the experience of gynecology-oncologists. Both methods are reproducible and easy to apply to all women with adnexal masses and could be used by general gynecologists to select women for laparoscopic surgery; however, referral to a gynecology-oncologist is advisable when there is any doubt. PMID:25392617

  13. Relaxation Methods for Strictly Convex Regularizations of Piecewise Linear Programs

    International Nuclear Information System (INIS)

    Kiwiel, K. C.

    1998-01-01

    We give an algorithm for minimizing the sum of a strictly convex function and a convex piecewise linear function. It extends several dual coordinate ascent methods for large-scale linearly constrained problems that occur in entropy maximization, quadratic programming, and network flows. In particular, it may solve exact penalty versions of such (possibly inconsistent) problems, and subproblems of bundle methods for nondifferentiable optimization. It is simple, can exploit sparsity, and in certain cases is highly parallelizable. Its global convergence is established in the recent framework of B -functions (generalized Bregman functions)

  14. Performance requirements of the MedAustron beam delivery system

    CERN Document Server

    AUTHOR|(CDS)2073034

    The Austrian hadron therapy center MedAustron is currently under construction with patient treatment planned to commence in 2015. Tumors will be irradiated using proton and carbon ions, for which the steeply rising Bragg curve and finite range offer a better conformity of the dose to the geometrical shape of the tumor compared to conventional photon irradiation. The current trend is to move from passive scattering toward active scanning using a narrow pencil beam in order to reach an even better dose conformation and limit the need of patient specific hardware. The quality of the deposited dose will ultimately depend on the performance of the beam delivery chain: beam profile and extraction stability of the extracted beam, accuracy and ramp rate of the scanning magnet power supplies, and precision of the beam monitors used for verifying the delivered dose. With a sharp lateral penumbra, the transverse dose fall-off can be minimized. This is of particular importance in situations where the lesion is adjace...

  15. Frequency effect on p-nitrophenol degradation under conditions of strict acoustic and electric control

    Directory of Open Access Journals (Sweden)

    Chang-ping Zhu

    2011-03-01

    Full Text Available The process of decomposing p-nitrophenol (PNP with power ultrasound requires strict control of acoustic and electric conditions. In this study, the conditions, including acoustic power and acoustic intensity, but not ultrasonic frequency, were controlled strictly at constant levels. The absorbency and the COD concentrations of the samples were measured in order to show the variation of the sample concentration. The results show significant differences in the trend of the solution degradation rate as acoustic power increases after the PNP solution (with a concentration of 114 mg/L and a pH value of 5.4 is irradiated for 60 min with ultrasonic frequencies of 530.8 kHz, 610.6 kHz, 855.0 kHz, and 1 130.0 kHz. The degradation rate of the solution increases with time and acoustic power (acoustic intensity. On the other hand, the degradation rate of the solution is distinctly dependent on frequency when the acoustic power and intensity are strictly controlled and maintained at constant levels. The degradation rate of the PNP solution declines with ultrasonic frequencies of 530.8 kHz, 610.6 kHz, 855.0 kHz, and 1 130.0 kHz; the COD concentration, on the contrary, increase.

  16. Non-strictly black body spectrum from the tunnelling mechanism

    International Nuclear Information System (INIS)

    Corda, Christian

    2013-01-01

    The tunnelling mechanism is widely used to explain Hawking radiation. However, in many cases the analysis used to obtain the Hawking temperature only involves comparing the emission probability for an outgoing particle with the Boltzmann factor. Banerjee and Majhi improved this approach by explicitly finding a black body spectrum associated with black holes. Their result, obtained using a reformulation of the tunnelling mechanism, is in contrast to that of Parikh and Wilczek, who found an emission probability that is compatible with a non-strictly thermal spectrum. Using the recently identified effective state for a black hole, we solve this contradiction via a slight modification of the analysis by Banerjee and Majhi. The final result is a non-strictly black body spectrum from the tunnelling mechanism. We also show that for an effective temperature, we can express the corresponding effective metric using Hawking’s periodicity arguments. Potential important implications for the black hole information puzzle are discussed. -- Highlights: •We review an important result by Banerjee and Majhi on the tunnelling mechanism in the framework of Hawking radiation. •This result is in contrast to another result reported by Parikh and Wilczek. •We introduce the effective state of a black hole. •We explain the contrast via a slight modification of the analysis by Banerjee and Majhi. •We discuss potential important implications for the black hole information puzzle

  17. 13 CFR 126.700 - What are the performance of work requirements for HUBZone contracts?

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What are the performance of work requirements for HUBZone contracts? 126.700 Section 126.700 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION HUBZONE PROGRAM Contract Performance Requirements § 126.700 What are the performance of work...

  18. Effects of a strict cutoff on Quantum Field Theory

    International Nuclear Information System (INIS)

    Sturnfield, J.F.

    1987-01-01

    Standard Quantum Field Theory has a number of integrals which are infinite. Although these are eliminated for some cases by renormalization, this aspect of the theory is not fully satisfactory. A number of theories with fundamental lengths have been introduced as alternatives and it would be useful to be able to distinguish between them. In particular, the effects that a strict cutoff would have on Quantum Field Theory is studied. It is noted that care must be taken in the method used to apply a strict cutoff. This lead to considering a theory where the cutoffs are defined by restricting each internal line. This theory is only piece-wise analytic. The resulting scattering matrix is frame dependent, yet the theory still satisfies the special relativity view that all frames are subjectively identical. The renormalization of this theory is finite. The change in mass from the electron self-energy will be a spinor operator. The main distinctions of this theory from standard theory will occur at super high energies. New poles and resonances which arise from new endpoint singularities will be found. The locations of these singularities will be frame dependent. Some of these singularities will correspond to creations or interactions of the normal particles with tachyons. It will be shown that for the one loop diagram, the form of the cutoff singularities are closely related to the standard singularities. When there is more than one loop, there can appear some new type of behavior. In particular, a cube root type of behavior in the two loop self-energy diagram will be found. Also the asymptotic behavior of the ladder diagram is studied

  19. An Assessment of Performance and Condition Monitoring Requirements of Foreign Marine Diesel Propulsion Systems

    National Research Council Canada - National Science Library

    1982-01-01

    This report presents a synopsis of the requirements and recommended practices for diesel engine diagnostic, performance and condition monitoring systems for medium and slow speed diesel propulsion systems...

  20. Single molecule experiments challenge the strict wave-particle dualism of light.

    Science.gov (United States)

    Greulich, Karl Otto

    2010-01-21

    Single molecule techniques improve our understanding of the photon and light. If the single photon double slit experiment is performed at the "single photon limit" of a multi-atom light source, faint light pulses with more than one photon hamper the interpretation. Single molecules, quantum dots or defect centres in crystals should be used as light source. "Single photon detectors" do not meet their promise-only "photon number resolving single photon detectors" do so. Particularly, the accumulation time argument, the only safe basis for the postulate of a strictly particle like photon, has so far not yet been verified.

  1. Single Molecule Experiments Challenge the Strict Wave-Particle Dualism of Light

    Directory of Open Access Journals (Sweden)

    Karl Otto Greulich

    2010-01-01

    Full Text Available Single molecule techniques improve our understanding of the photon and light. If the single photon double slit experiment is performed at the “single photon limit” of a multi-atom light source, faint light pulses with more than one photon hamper the interpretation. Single molecules, quantum dots or defect centres in crystals should be used as light source. “Single photon detectors” do not meet their promise―only “photon number resolving single photon detectors” do so. Particularly, the accumulation time argument, the only safe basis for the postulate of a strictly particle like photon, has so far not yet been verified.

  2. 40 CFR 158.2160 - Microbial pesticides product performance data requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Microbial pesticides product... AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Microbial Pesticides § 158.2160 Microbial pesticides product performance data requirements. Product performance data must be developed for...

  3. Performance-Based Competency Requirements for Student Teachers and How to Assess Them

    NARCIS (Netherlands)

    Leijen, Ali; Slof, B.|info:eu-repo/dai/nl/296567132; L, Malva; P., Hunt,; van Tartwijk, J.W.F.|info:eu-repo/dai/nl/112629385; van der Schaaf, M.F.|info:eu-repo/dai/nl/073361917

    2017-01-01

    This paper reports a validation study of the performance-based competency requirements model for initial teacher education. An assessment rubric of student teachers’ performance-based competency requirements was developed in collaboration between Dutch and Estonian researchers and teacher educators.

  4. 10 CFR 34.20 - Performance requirements for industrial radiography equipment.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Performance requirements for industrial radiography equipment. 34.20 Section 34.20 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL RADIOGRAPHIC OPERATIONS Equipment § 34.20 Performance...

  5. 42 CFR 456.245 - Number of studies required to be performed.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Number of studies required to be performed. 456.245 Section 456.245 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Ur Plan: Medical Care Evaluation Studies § 456.245 Number of studies required to be performed. The...

  6. 42 CFR 456.145 - Number of studies required to be performed.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Number of studies required to be performed. 456.145 Section 456.145 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN...: Medical Care Evaluation Studies § 456.145 Number of studies required to be performed. The hospital must...

  7. Assessing students' performance in software requirements engineering education using scoring rubrics

    Science.gov (United States)

    Mkpojiogu, Emmanuel O. C.; Hussain, Azham

    2017-10-01

    The study investigates how helpful the use of scoring rubrics is, in the performance assessment of software requirements engineering students and whether its use can lead to students' performance improvement in the development of software requirements artifacts and models. Scoring rubrics were used by two instructors to assess the cognitive performance of a student in the design and development of software requirements artifacts. The study results indicate that the use of scoring rubrics is very helpful in objectively assessing the performance of software requirements or software engineering students. Furthermore, the results revealed that the use of scoring rubrics can also produce a good achievement assessments direction showing whether a student is either improving or not in a repeated or iterative assessment. In a nutshell, its use leads to the performance improvement of students. The results provided some insights for further investigation and will be beneficial to researchers, requirements engineers, system designers, developers and project managers.

  8. 7 CFR 28.414 - Strict Low Middling Light Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... CONTAINER REGULATIONS COTTON CLASSING, TESTING, AND STANDARDS Standards Light Spotted Cotton § 28.414 Strict Low Middling Light Spotted Color. Strict Low Middling Light Spotted Color is color which in spot or...

  9. On N. Chomsky’s strict subcategorization of verbs

    Directory of Open Access Journals (Sweden)

    Janez Orešnik

    1966-12-01

    Full Text Available This paper studies the so-called strict subcategorization rules, and the theory associated with them, in the transformational grammar of. Erigl·ish as proposed by Noarn Chomsky in his Aspects. The syntactic component of English transformational grammar consists of two mutually ordered parts, viz., the base and the transformational subcomponents. The initial part of the base are the so-called categorial rules, which are of almost exclusive interest to us here. Their primary task is to generate what are usually called basic sentence patterns, and will here, with Chomsky (Aspects, p.ll3, be designated with the expression, frames of category symbols.- The rules of the transformational subcomponent modify, in various ways, the frames generated by the base. For several reasons - one of them being that the correct work of the transformational subcomponent quite often depends on the kind of lexical items with which the syntactic positions in the frames of category symbols have been filled, the lexical items must be introduced from the lexicon into the empty positions in the frames before the rules of the transformational subcomponent can be allowed to modify the frames.

  10. Effects of strict prolonged bed rest on cardiorespiratory fitness

    DEFF Research Database (Denmark)

    Ried-Larsen, Mathias; Aarts, Hugo M; Joyner, Michael J

    2017-01-01

    with larger declines in V̇o2max). Furthermore, the systematic review revealed a gap in the knowledge about the cardiovascular response to extreme physical inactivity, particularly in older subjects and women of any age group. In addition to its relevance to spaceflight, this lack of data has significant....... Since 1949, 80 studies with a total of 949 participants (>90% men) have been published with data on strict bed rest and V̇o2max The studies were conducted mainly in young participants [median age (interquartile range) 24.5 (22.4-34.0) yr]. The duration of bed rest ranged from 1 to 90 days. V̇o2max...... declined linearly across bed rest duration. No statistical difference in the decline among studies reporting V̇o2max as l/min (-0.3% per day) compared with studies reporting V̇o2max normalized to body weight (ml·kg-1·min-1; -0.43% per day) was observed. Although both total body weight and lean body mass...

  11. Fixed point iterations for strictly hemi-contractive maps in uniformly smooth Banach spaces

    International Nuclear Information System (INIS)

    Chidume, C.E.; Osilike, M.O.

    1993-05-01

    It is proved that the Mann iteration process converges strongly to the fixed point of a strictly hemi-contractive map in real uniformly smooth Banach spaces. The class of strictly hemi-contractive maps includes all strictly pseudo-contractive maps with nonempty fixed point sets. A related result deals with the Ishikawa iteration scheme when the mapping is Lipschitzian and strictly hemi-contractive. Our theorems generalize important known results. (author). 29 refs

  12. Cost optimal building performance requirements. Calculation methodology for reporting on national energy performance requirements on the basis of cost optimality within the framework of the EPBD

    Energy Technology Data Exchange (ETDEWEB)

    Boermans, T.; Bettgenhaeuser, K.; Hermelink, A.; Schimschar, S. [Ecofys, Utrecht (Netherlands)

    2011-05-15

    On the European level, the principles for the requirements for the energy performance of buildings are set by the Energy Performance of Buildings Directive (EPBD). Dating from December 2002, the EPBD has set a common framework from which the individual Member States in the EU developed or adapted their individual national regulations. The EPBD in 2008 and 2009 underwent a recast procedure, with final political agreement having been reached in November 2009. The new Directive was then formally adopted on May 19, 2010. Among other clarifications and new provisions, the EPBD recast introduces a benchmarking mechanism for national energy performance requirements for the purpose of determining cost-optimal levels to be used by Member States for comparing and setting these requirements. The previous EPBD set out a general framework to assess the energy performance of buildings and required Member States to define maximum values for energy delivered to meet the energy demand associated with the standardised use of the building. However it did not contain requirements or guidance related to the ambition level of such requirements. As a consequence, building regulations in the various Member States have been developed by the use of different approaches (influenced by different building traditions, political processes and individual market conditions) and resulted in different ambition levels where in many cases cost optimality principles could justify higher ambitions. The EPBD recast now requests that Member States shall ensure that minimum energy performance requirements for buildings are set 'with a view to achieving cost-optimal levels'. The cost optimum level shall be calculated in accordance with a comparative methodology. The objective of this report is to contribute to the ongoing discussion in Europe around the details of such a methodology by describing possible details on how to calculate cost optimal levels and pointing towards important factors and

  13. Effects of growth temperature and strictly anaerobic recovery on the survival of Listeria monocytogenes during pasteurization.

    Science.gov (United States)

    Knabel, S J; Walker, H W; Hartman, P A; Mendonca, A F

    1990-02-01

    Listeria monocytogenes F5069 was suspended in either Trypticase soy broth-0.6% yeast extract (TSBYE) or sterile, whole milk and heated at 62.8 degrees C in sealed thermal death time tubes. Severely heat-injured cells were recovered in TSBYE within sealed thermal death time tubes because of the formation of reduced conditions in the depths of the TSBYE. Also, the use of strictly anaerobic Hungate techniques significantly increased recovery in TSBYE containing 1.5% agar compared with aerobically incubated controls. The exogenous addition of catalase, but not superoxide dismutase, slightly increased the recovery of heat-injured cells in TSBYE containing 1.5% agar incubated aerobically. Growth of cells at 43 degrees C caused a greater increase in heat resistance as compared with cells heat shocked at 43 degrees C or cells grown at lower temperatures. Growth of L. monocytogenes at 43 degrees C and enumeration by the use of strictly anaerobic Hungate techniques resulted in D62.8 degrees C values that were at least sixfold greater than those previously obtained by using cells grown at 37 degrees C and aerobic plating. Results indicate that, under the conditions of the present study, high levels of L. monocytogenes would survive the minimum low-temperature, long-time treatment required by the U.S. Food and Drug Administration for pasteurizing milk. The possible survival of low levels of L. monocytogenes during high-temperature, short-time pasteurization and enumeration of injured cells by recovery on selective media under strictly anaerobic conditions are discussed.

  14. Analytical Performance Requirements for Systems for Self-Monitoring of Blood Glucose With Focus on System Accuracy

    Science.gov (United States)

    Freckmann, Guido; Schmid, Christina; Baumstark, Annette; Rutschmann, Malte; Haug, Cornelia; Heinemann, Lutz

    2015-01-01

    In the European Union (EU), the ISO (International Organization for Standardization) 15197 standard is applicable for the evaluation of systems for self-monitoring of blood glucose (SMBG) before the market approval. In 2013, a revised version of this standard was published. Relevant revisions in the analytical performance requirements are the inclusion of the evaluation of influence quantities, for example, hematocrit, and some changes in the testing procedures for measurement precision and system accuracy evaluation, for example, number of test strip lots. Regarding system accuracy evaluation, the most important change is the inclusion of more stringent accuracy criteria. In 2014, the Food and Drug Administration (FDA) in the United States published their own guidance document for the premarket evaluation of SMBG systems with even more stringent system accuracy criteria than stipulated by ISO 15197:2013. The establishment of strict accuracy criteria applicable for the premarket evaluation is a possible approach to further improve the measurement quality of SMBG systems. However, the system accuracy testing procedure is quite complex, and some critical aspects, for example, systematic measurement difference between the reference measurement procedure and a higher-order procedure, may potentially limit the apparent accuracy of a given system. Therefore, the implementation of a harmonized reference measurement procedure for which traceability to standards of higher order is verified through an unbroken, documented chain of calibrations is desirable. In addition, the establishment of regular and standardized post-marketing evaluations of distributed test strip lots should be considered as an approach toward an improved measurement quality of available SMBG systems. PMID:25872965

  15. Application of systems engineering to determine performance requirements for repository waste packages

    International Nuclear Information System (INIS)

    Aitken, E.A.; Stimmell, G.L.

    1987-01-01

    The waste package for a nuclear waste repository in salt must contribute substantially to the performance objectives defined by the Salt Repository Project (SRP) general requirements document governing disposal of high-level waste. The waste package is one of the engineered barriers providing containment. In establishing the performance requirements for a project focused on design and fabrication of the waste package, the systems engineering methodology has been used to translate the hierarchy requirements for the repository system to specific performance requirements for design and fabrication of the waste package, a subsystem of the repository. This activity is ongoing and requires a methodology that provides traceability and is capable of iteration as baseline requirements are refined or changed. The purpose of this summary is to describe the methodology being used and the way it can be applied to similar activities in the nuclear industry

  16. Strict or graduated punishment? Effect of punishment strictness on the evolution of cooperation in continuous public goods games.

    Directory of Open Access Journals (Sweden)

    Hajime Shimao

    Full Text Available Whether costly punishment encourages cooperation is one of the principal questions in studies on the evolution of cooperation and social sciences. In society, punishment helps deter people from flouting rules in institutions. Specifically, graduated punishment is a design principle for long-enduring common-pool resource institutions. In this study, we investigate whether graduated punishment can promote a higher cooperation level when each individual plays the public goods game and has the opportunity to punish others whose cooperation levels fall below the punisher's threshold. We then examine how spatial structure affects evolutionary dynamics when each individual dies inversely proportional to the game score resulting from the social interaction and another player is randomly chosen from the population to produce offspring to fill the empty site created after a player's death. Our evolutionary simulation outcomes demonstrate that stricter punishment promotes increased cooperation more than graduated punishment in a spatially structured population, whereas graduated punishment increases cooperation more than strict punishment when players interact with randomly chosen opponents from the population. The mathematical analysis also supports the results.

  17. Strict or Graduated Punishment? Effect of Punishment Strictness on the Evolution of Cooperation in Continuous Public Goods Games

    Science.gov (United States)

    Shimao, Hajime; Nakamaru, Mayuko

    2013-01-01

    Whether costly punishment encourages cooperation is one of the principal questions in studies on the evolution of cooperation and social sciences. In society, punishment helps deter people from flouting rules in institutions. Specifically, graduated punishment is a design principle for long-enduring common-pool resource institutions. In this study, we investigate whether graduated punishment can promote a higher cooperation level when each individual plays the public goods game and has the opportunity to punish others whose cooperation levels fall below the punisher’s threshold. We then examine how spatial structure affects evolutionary dynamics when each individual dies inversely proportional to the game score resulting from the social interaction and another player is randomly chosen from the population to produce offspring to fill the empty site created after a player’s death. Our evolutionary simulation outcomes demonstrate that stricter punishment promotes increased cooperation more than graduated punishment in a spatially structured population, whereas graduated punishment increases cooperation more than strict punishment when players interact with randomly chosen opponents from the population. The mathematical analysis also supports the results. PMID:23555826

  18. Exploration of the Trade Space Between Unmanned Aircraft Systems Descent Maneuver Performance and Sense-and-Avoid System Performance Requirements

    Science.gov (United States)

    Jack, Devin P.; Hoffler, Keith D.; Johnson, Sally C.

    2014-01-01

    A need exists to safely integrate Unmanned Aircraft Systems (UAS) into the United States' National Airspace System. Replacing manned aircraft's see-and-avoid capability in the absence of an onboard pilot is one of the key challenges associated with safe integration. Sense-and-avoid (SAA) systems will have to achieve yet-to-be-determined required separation distances for a wide range of encounters. They will also need to account for the maneuver performance of the UAS they are paired with. The work described in this paper is aimed at developing an understanding of the trade space between UAS maneuver performance and SAA system performance requirements, focusing on a descent avoidance maneuver. An assessment of current manned and unmanned aircraft performance was used to establish potential UAS performance test matrix bounds. Then, near-term UAS integration work was used to narrow down the scope. A simulator was developed with sufficient fidelity to assess SAA system performance requirements. The simulator generates closest-point-of-approach (CPA) data from the wide range of UAS performance models maneuvering against a single intruder with various encounter geometries. Initial attempts to model the results made it clear that developing maneuver performance groups is required. Discussion of the performance groups developed and how to know in which group an aircraft belongs for a given flight condition and encounter is included. The groups are airplane, flight condition, and encounter specific, rather than airplane-only specific. Results and methodology for developing UAS maneuver performance requirements are presented for a descent avoidance maneuver. Results for the descent maneuver indicate that a minimum specific excess power magnitude can assure a minimum CPA for a given time-to-go prediction. However, smaller amounts of specific excess power may achieve or exceed the same CPA if the UAS has sufficient speed to trade for altitude. The results of this study will

  19. [Precautions of physical performance requirements and test methods during product standard drafting process of medical devices].

    Science.gov (United States)

    Song, Jin-Zi; Wan, Min; Xu, Hui; Yao, Xiu-Jun; Zhang, Bo; Wang, Jin-Hong

    2009-09-01

    The major idea of this article is to discuss standardization and normalization for the product standard of medical devices. Analyze the problem related to the physical performance requirements and test methods during product standard drafting process and make corresponding suggestions.

  20. 42 CFR 84.1140 - Dust, fume, and mist respirators; performance requirements; general.

    Science.gov (United States)

    2010-10-01

    ... PROTECTIVE DEVICES Dust, Fume, and Mist; Pesticide; Paint Spray; Powered Air-Purifying High Efficiency Respirators and Combination Gas Masks § 84.1140 Dust, fume, and mist respirators; performance requirements...

  1. 40 CFR 80.815 - What are the gasoline toxics performance requirements for refiners and importers?

    Science.gov (United States)

    2010-07-01

    ... toxics requirements of this subpart apply separately for each of the following types of gasoline produced...) The gasoline toxics performance requirements of this subpart apply to gasoline produced at a refinery... not apply to gasoline produced by a refinery approved under § 80.1334, pursuant to § 80.1334(c). (2...

  2. 10 CFR Appendix II to Part 960 - NRC and EPA Requirements for Preclosure Repository Performance

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false NRC and EPA Requirements for Preclosure Repository... SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. II Appendix II to Part 960—NRC and EPA Requirements for Preclosure Repository Performance Under proposed 40 CFR part 191, subpart A...

  3. On Electrical Design and Technical Performance Requirements for Large Scale Wind Farms

    DEFF Research Database (Denmark)

    Gordon, Mark; Keerthipala, W.; Fernando, A.

    2009-01-01

    plant operating limits for ensuring power system security at the high voltage point of connection. Experiences presented here refer mainly to few of the selected technical requirements and issues encountered during the process of wind farms connections into Eastern Australian power system. In particular......This paper presents and discusses technical performance requirements for connection of large scale wind turbine generating systems into HV transmission networks. Requirements have been presented for the purpose of achieving performance enhanced operation, reliability and assessment of the power...

  4. 46 CFR 160.037-3 - Materials, workmanship, construction, and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, workmanship, construction, and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand Orange Smoke Distress Signals § 160.037-3 Materials, workmanship, construction, and performance requirements. (a...

  5. 46 CFR 160.021-3 - Materials, workmanship, construction and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, workmanship, construction and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand Red Flare Distress Signals § 160.021-3 Materials, workmanship, construction and performance requirements. (a...

  6. Performance requirements for the double-shell tank system: Phase 1

    International Nuclear Information System (INIS)

    Claghorn, R.D.

    1998-01-01

    This document establishes performance requirements for the double-shell tank system. These requirements, in turn, will be incorporated in the System Specification for the Double-Shell Tank System (Grenard and Claghorn 1998). This version of the document establishes requirements that are applicable to the first phase (Phase 1) of the Tank Waste Remediation System (TWRS) mission described in the TWRS Mission Analysis Report (Acree 1998). It does not specify requirements for either the Phase 2 mission or the double-shell tank system closure period

  7. Input data requirements for performance modelling and monitoring of photovoltaic plants

    DEFF Research Database (Denmark)

    Gavriluta, Anamaria Florina; Spataru, Sergiu; Sera, Dezso

    2018-01-01

    This work investigates the input data requirements in the context of performance modeling of thin-film photovoltaic (PV) systems. The analysis focuses on the PVWatts performance model, well suited for on-line performance monitoring of PV strings, due to its low number of parameters and high...... accuracy. The work aims to identify the minimum amount of input data required for parameterizing an accurate model of the PV plant. The analysis was carried out for both amorphous silicon (a-Si) and cadmium telluride (CdTe), using crystalline silicon (c-Si) as a base for comparison. In the studied cases...

  8. The Success Rate of Initial {sup 131I} Ablation in Differentiated Thyroid Cancer: Comparison Between Less strict and Very Strict Low Iodine Diets

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Ik Dong; Kim, Sung Hoon; Seo, Ye Young; Oh, Jin Kyoung; O, Joo Hyun; Chung, Soo Kyo [The Catholic Univ. of Korea, Seoul (Korea, Republic of)

    2012-03-15

    To decrease the risk of recurrence or metastasis in differentiated thyroid cancer (DTC), selected patients receive radioactive iodine ablation of remnant thyroid tissue or tumor. A low iodine diet can enhance uptake of radioactive iodine. We compared the success rates of radioactive iodine ablation therapy in patients who followed two different low iodine diets (LIDs). The success rates of postsurgical radioactive iodine ablation in DTC patients receiving empiric doses of 150 mCi were retrospectively reviewed. First-time radioactive iodine ablation therapy was done in 71 patients following less strict LID. Less strict LID restricted seafood, iodized salt, egg yolk, dairy products, processed meat, instant prepared meals, and multivitamins. Very strict LID additionally restricted rice, freshwater fish, spinach, and soybean products. Radioactive iodine ablation therapy was considered successful when follow up {sup 123I} whole body scan was negative and stimulated serum thyroglobulin level was less than 2.0 ng/mL. The success rate of patients following less strict LID was 80.3% and for very strict LID 75.6%. There was no statistically significant difference in the success rates between the two LID groups (P=0.48). Very strict LID may not contribute to improving the success rate of initial radioactive iodine ablation therapy at the cost of great inconvenience to the patient.

  9. L-Band Digital Aeronautical Communications System Engineering - Concepts of Use, Systems Performance, Requirements, and Architectures

    Science.gov (United States)

    Zelkin, Natalie; Henriksen, Stephen

    2010-01-01

    This NASA Contractor Report summarizes and documents the work performed to develop concepts of use (ConUse) and high-level system requirements and architecture for the proposed L-band (960 to 1164 MHz) terrestrial en route communications system. This work was completed as a follow-on to the technology assessment conducted by NASA Glenn Research Center and ITT for the Future Communications Study (FCS). ITT assessed air-to-ground (A/G) communications concepts of use and operations presented in relevant NAS-level, international, and NAS-system-level documents to derive the appropriate ConUse relevant to potential A/G communications applications and services for domestic continental airspace. ITT also leveraged prior concepts of use developed during the earlier phases of the FCS. A middle-out functional architecture was adopted by merging the functional system requirements identified in the bottom-up assessment of existing requirements with those derived as a result of the top-down analysis of ConUse and higher level functional requirements. Initial end-to-end system performance requirements were derived to define system capabilities based on the functional requirements and on NAS-SR-1000 and the Operational Performance Assessment conducted as part of the COCR. A high-level notional architecture of the L-DACS supporting A/G communication was derived from the functional architecture and requirements.

  10. Selvester scoring in patients with strict LBBB using the QUARESS software.

    Science.gov (United States)

    Xia, Xiaojuan; Chaudhry, Uzma; Wieslander, Björn; Borgquist, Rasmus; Wagner, Galen S; Strauss, David G; Platonov, Pyotr; Ugander, Martin; Couderc, Jean-Philippe

    2015-01-01

    Estimation of the infarct size from body-surface ECGs in post-myocardial infarction patients has become possible using the Selvester scoring method. Automation of this scoring has been proposed in order to speed-up the measurement of the score and improving the inter-observer variability in computing a score that requires strong expertise in electrocardiography. In this work, we evaluated the quality of the QuAReSS software for delivering correct Selvester scoring in a set of standard 12-lead ECGs. Standard 12-lead ECGs were recorded in 105 post-MI patients prescribed implantation of an implantable cardiodefibrillator (ICD). Amongst the 105 patients with standard clinical left bundle branch block (LBBB) patterns, 67 had a LBBB pattern meeting the strict criteria. The QuAReSS software was applied to these 67 tracings by two independent groups of cardiologists (from a clinical group and an ECG core laboratory) to measure the Selvester score semi-automatically. Using various level of agreement metrics, we compared the scores between groups and when automatically measured by the software. The average of the absolute difference in Selvester scores measured by the two independent groups was 1.4±1.5 score points, whereas the difference between automatic method and the two manual adjudications were 1.2±1.2 and 1.3±1.2 points. Eighty-two percent score agreement was observed between the two independent measurements when the difference of score was within two point ranges, while 90% and 84% score agreements were reached using the automatic method compared to the two manual adjudications. The study confirms that the QuAReSS software provides valid measurements of the Selvester score in patients with strict LBBB with minimal correction from cardiologists. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Evaluation of a strict protocol approach in managing women with ...

    African Journals Online (AJOL)

    3. Respiratory system. Respiratory rate, lung sounds and oxygen saturation. If the respiratory rate was increased, the oxygen saturation decreased or lung sounds were abnormal, arterial blood gas measurement and a chest X-ray was performed. 4. The hepatic system was evaluated by examining for jaundice and signs of ...

  12. 15 TOWARDS THE STRICT LEGAL ENFORCEMENT OF BEST ...

    African Journals Online (AJOL)

    Fr. Ikenga

    production has the potential to cause severe environmental degradation, not only to the physical environment, but also to ... approaches to achieving high environmental performance in the oil and gas sector and made some ..... bribes; the number of forums organised to discuss employee conditions; and the level of local.

  13. Prerequisites, requirements, stresses and strains, training and performance tests for the horses

    OpenAIRE

    Westermann, Katharina

    2013-01-01

    One aim of this study was to investigate the emphasis (requirements, stresses and strains) and the actual qualifying (training guide, performance test) of horses in EAI. Another aim was to work out proposals for a standardizable quality management for those horses (development of a guideline for the utilisation and training as well as a performance test for horses in EAI, an instructor licence “EAI” for suppliers, additions to the education guidelines within the horse-related apprenticeships ...

  14. Construction products performances and basic requirements for fire safety of facades in energy rehabilitation of buildings

    Directory of Open Access Journals (Sweden)

    Laban Mirjana Đ.

    2015-01-01

    Full Text Available Construction product means any product or kit which is produced and placed on the market for incorporation in a permanent manner in construction works, or parts thereof, and the performance of which has an effect on the performance of the construction works with respect to the basic requirements for construction works. Safety in case of fire and Energy economy and heat retention represent two among seven basic requirements which building has to meet according to contemporary technical rules on planning and construction. Performances of external walls building materials (particularly reaction to fire could significantly affect to fire spread on the façade and other building parts. Therefore, façade shaping and materialization in building renewal process, has to meet the fire safety requirement, as well as the energy requirement. Brief survey of fire protection regulations development in Serbia is presented in the paper. Preventive measures for fire risk reduction in building façade energy renewal are proposed according to contemporary fire safety requirements.

  15. Validation of an automatic diagnosis of strict left bundle branch block criteria using 12-lead electrocardiograms

    DEFF Research Database (Denmark)

    Xia, Xiaojuan; Ruwald, Anne-Christine; Ruwald, Martin H

    2017-01-01

    AIMS: Strict left bundle branch block (LBBB) criteria were recently proposed to identify LBBB patients to benefit most from cardiac resynchronization therapy (CRT). The aim of our study was to automate identification of strict LBBB in order to facilitate its broader application. METHODS: We devel...

  16. 7 CFR 28.416 - Strict Good Ordinary Light Spotted Color.

    Science.gov (United States)

    2010-01-01

    ... CONTAINER REGULATIONS COTTON CLASSING, TESTING, AND STANDARDS Standards Light Spotted Cotton § 28.416 Strict Good Ordinary Light Spotted Color. Strict Good Ordinary Light Spotted Color is color which in spot or... Cotton Source: 57 FR 34498, Aug. 5, 1992, unless otherwise noted. ...

  17. 40 CFR 158.220 - Experimental use permit data requirements for product performance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Experimental use permit data requirements for product performance. 158.220 Section 158.220 Protection of Environment ENVIRONMENTAL... pesticide product bears a claim to control pest microorganisms that pose a threat to human health and whose...

  18. 40 CFR 158.2070 - Biochemical pesticides product performance data requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Biochemical pesticides product performance data requirements. 158.2070 Section 158.2070 Protection of Environment ENVIRONMENTAL PROTECTION... efficacy data unless the pesticide product bears a claim to control public health pests, such as pest...

  19. 29 CFR 1620.16 - Jobs requiring equal effort in performance.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Jobs requiring equal effort in performance. 1620.16 Section 1620.16 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION THE... factors which cause mental fatigue and stress, as well as those which alleviate fatigue, are to be...

  20. 42 CFR 460.134 - Minimum requirements for quality assessment and performance improvement program.

    Science.gov (United States)

    2010-10-01

    ... well being. (ii) Functional status. (iii) Cognitive ability. (iv) Social/behavioral functioning. (v... 42 Public Health 4 2010-10-01 2010-10-01 false Minimum requirements for quality assessment and performance improvement program. 460.134 Section 460.134 Public Health CENTERS FOR MEDICARE & MEDICAID...

  1. 20 CFR 641.879 - What are the fiscal and performance reporting requirements for recipients?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What are the fiscal and performance reporting requirements for recipients? 641.879 Section 641.879 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION... Quarterly Progress Report (QPR) to the Department in electronic format via the Internet within 30 days after...

  2. 40 CFR Table 3 to Subpart Lllll of... - Requirements for Performance Tests a,b

    Science.gov (United States)

    2010-07-01

    ... particulate matter, total hydrocarbon, carbon monoxide, and carbon dioxide emission tests a. Select sampling... particulate matter, total hydrocarbon, carbon monoxide, and carbon dioxide emission tests Measure moisture... 40 Protection of Environment 13 2010-07-01 2010-07-01 false Requirements for Performance Tests a,b...

  3. 76 FR 52669 - Report on the Performance of Drug and Biologics Firms in Conducting Postmarketing Requirements...

    Science.gov (United States)

    2011-08-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0332] Report on the Performance of Drug and Biologics Firms in Conducting Postmarketing Requirements and Commitments; Availability; Correction AGENCY: Food and Drug Administration, HHS. ACTION: Notice of...

  4. Estimation of waste package performance requirements for a nuclear waste repository in basalt

    International Nuclear Information System (INIS)

    Wood, B.J.

    1980-07-01

    A method of developing waste package performance requirements for specific nuclides is described, and based on federal regulations concerning permissible concentrations in solution at the point of discharge to the accessible environment, a simple and conservative transport model, and baseline and potential worst-case release scenarios

  5. Requirements for high performance computing for lattice QCD. Report of the ECFA working panel

    International Nuclear Information System (INIS)

    Jegerlehner, F.; Kenway, R.D.; Martinelli, G.; Michael, C.; Pene, O.; Petersson, B.; Petronzio, R.; Sachrajda, C.T.; Schilling, K.

    2000-01-01

    This report, prepared at the request of the European Committee for Future Accelerators (ECFA), contains an assessment of the High Performance Computing resources which will be required in coming years by European physicists working in Lattice Field Theory and a review of the scientific opportunities which these resources would open. (orig.)

  6. Comparison of exertion required to perform standard and active compression-decompression cardiopulmonary resuscitation.

    Science.gov (United States)

    Shultz, J J; Mianulli, M J; Gisch, T M; Coffeen, P R; Haidet, G C; Lurie, K G

    1995-02-01

    Active compression-decompression (ACD) cardiopulmonary resuscitation (CPR) utilizes a hand-held suction device with a pressure gauge that enables the operator to compress as well as actively decompress the chest. This new CPR method improves hemodynamic and ventilatory parameters when compared with standard CPR. ACD-CPR is easy to perform but may be more labor intensive. The purpose of this study was to quantify and compare the work required to perform ACD and standard CPR. Cardiopulmonary testing was performed on six basic cardiac life support- and ACD-trained St. Paul, MN fire-fighter personnel during performance of 10 min each of ACD and standard CPR on a mannequin equipped with a compression gauge. The order of CPR techniques was determined randomly with > 1 h between each study. Each CPR method was performed at 80 compressions/min (timed with a metronome), to a depth of 1.5-2 inches, and with a 50% duty cycle. Baseline cardiopulmonary measurements were similar at rest prior to performance of both CPR methods. During standard and ACD-CPR, respectively, rate-pressure product was 18.2 +/- 3.0 vs. 23.8 +/- 1.7 (x 1000, P CPR compared with standard CPR. Both methods require subanaerobic energy expenditure and can therefore be sustained for a sufficient length of time by most individuals to optimize resuscitation efforts. Due to the slightly higher work requirement, ACD-CPR may be more difficult to perform compared with standard CPR for long periods of time, particularly by individuals unaccustomed to the workload requirement of CPR, in general.

  7. Applying Required Navigation Performance Concept for Traffic Management of Small Unmanned Aircraft Systems

    Science.gov (United States)

    Jung, Jaewoo; D'Souza, Sarah N.; Johnson, Marcus A.; Ishihara, Abraham K.; Modi, Hemil C.; Nikaido, Ben; Hasseeb, Hashmatullah

    2016-01-01

    In anticipation of a rapid increase in the number of civil Unmanned Aircraft System(UAS) operations, NASA is researching prototype technologies for a UAS Traffic Management (UTM) system that will investigate airspace integration requirements for enabling safe, efficient low-altitude operations. One aspect a UTM system must consider is the correlation between UAS operations (such as vehicles, operation areas and durations), UAS performance requirements, and the risk to people and property in the operational area. This paper investigates the potential application of the International Civil Aviation Organizations (ICAO) Required Navigation Performance (RNP) concept to relate operational risk with trajectory conformance requirements. The approach is to first define a method to quantify operational risk and then define the RNP level requirement as a function of the operational risk. Greater operational risk corresponds to more accurate RNP level, or smaller tolerable Total System Error (TSE). Data from 19 small UAS flights are used to develop and validate a formula that defines this relationship. An approach to assessing UAS-RNP conformance capability using vehicle modeling and wind field simulation is developed to investigate how this formula may be applied in a future UTM system. The results indicate the modeled vehicles flight path is robust to the simulated wind variation, and it can meet RNP level requirements calculated by the formula. The results also indicate how vehicle-modeling fidelity may be improved to adequately verify assessed RNP level.

  8. Reliability Capacity of Half-Duplex Channels with Strict Deadlines

    DEFF Research Database (Denmark)

    Costa, Rui; Roetter, Daniel Enrique Lucani; Vinhoza, Tiago

    2015-01-01

    of transmissions and provide closed-form upper and lower bounds for this capacity. We show that the reliability capacity converges to the capacity of a classical erasure channel as the deadline constraint is relaxed. In our framework, the effect of feedback is analyzed both in terms of the reliability capacity...... and in terms of its advantages towards the mean number of packets that can be transmitted reliably. Optimal schemes for leveraging feedback are presented and the results show that a judicious use of even a single feedback packet can have a significant impact on the mean performance....

  9. Use of simple transport equations to estimate waste package performance requirements

    International Nuclear Information System (INIS)

    Wood, B.J.

    1982-01-01

    A method of developing waste package performance requirements for specific nuclides is described. The method is based on: Federal regulations concerning permissible concentrations in solution at the point of discharge to the accessible environment; a simple and conservative transport model; baseline and potential worst-case release scenarios. Use of the transport model enables calculation of maximum permissible release rates within a repository in basalt for each of the scenarios. The maximum permissible release rates correspond to performance requirements for the engineered barrier system. The repository was assumed to be constructed in a basalt layer. For the cases considered, including a well drilled into an aquifer 1750 m from the repository center, little significant advantage is obtained from a 1000-yr as opposed to a 100-yr waste package. A 1000-yr waste package is of importance only for nuclides with half-lives much less than 100 yr which travel to the accessible environment in much less than 1000 yr. Such short travel times are extremely unlikely for a mined repository. Among the actinides, the most stringent maximum permissible release rates are for 236 U and 234 U. A simple solubility calculation suggests, however, that these performance requirements can be readily met by the engineered barrier system. Under the reducing conditions likely to occur in a repository located in basalt, uranium would be sufficiently insoluble that no solution could contain more than about 0.01% of the maximum permissible concentration at saturation. The performance requirements derived from the one-dimensional modeling approach are conservative by at least one to two orders of magnitude. More quantitative three-dimensional modeling at specific sites should enable relaxation of the performance criteria derived in this study. 12 references, 8 figures, 8 tables

  10. Are strict vegetarians protected against prostate cancer?1

    Science.gov (United States)

    Knutsen, Synnove F; Knutsen, Raymond; Jacobsen, Bjarne K; Fan, Jing; Beeson, W Lawrence; Sabate, Joan; Hadley, David; Jaceldo-Siegl, Karen; Penniecook, Jason; Herring, Patti; Butler, Terry; Bennett, Hanni; Fraser, Gary

    2016-01-01

    Background: According to the American Cancer Society, prostate cancer accounts for ∼27% of all incident cancer cases among men and is the second most common (noncutaneous) cancer among men. The relation between diet and prostate cancer is still unclear. Because people do not consume individual foods but rather foods in combination, the assessment of dietary patterns may offer valuable information when determining associations between diet and prostate cancer risk. Objective: This study aimed to examine the association between dietary patterns (nonvegetarian, lacto-ovo-vegetarian, pesco-vegetarian, vegan, and semi-vegetarian) and prostate cancer incidence among 26,346 male participants of the Adventist Health Study-2. Design: In this prospective cohort study, cancer cases were identified by matching to cancer registries. Cox proportional hazards regression analysis was performed to estimate HRs by using age as the time variable. Results: In total, 1079 incident prostate cancer cases were identified. Around 8% of the study population reported adherence to the vegan diet. Vegan diets showed a statistically significant protective association with prostate cancer risk (HR: 0.65; 95% CI: 0.49, 0.85). After stratifying by race, the statistically significant association with a vegan diet remained only for the whites (HR: 0.63; 95% CI: 0.46, 0.86), but the multivariate HR for black vegans showed a similar but nonsignificant point estimate (HR: 0.69; 95% CI: 0.41, 1.18). Conclusion: Vegan diets may confer a lower risk of prostate cancer. This lower estimated risk is seen in both white and black vegan subjects, although in the latter, the CI is wider and includes the null. PMID:26561618

  11. Conflict Resolution for Product Performance Requirements Based on Propagation Analysis in the Extension Theory

    Directory of Open Access Journals (Sweden)

    Yanwei Zhao

    2014-01-01

    Full Text Available Traditional product data mining methods are mainly focused on the static data. Performance requirements are generally met as possible by finding some cases and changing their structures. However, when one is satisfied with the structures changed, the other effects are not taken into account by analyzing the correlations; that is, design conflicts are not identified and resolved. An approach to resolving the conflict problems is proposed based on propagation analysis in Extension Theory. Firstly, the extension distance is improved to better fit evaluating the similarity among cases, then, a case retrieval method is developed. Secondly, the transformations that can be made on selected cases are formulated by understanding the conflict natures in the different performance requirements, which leads to the extension transformation strategy development for coordinating conflicts using propagation analysis. Thirdly, the effects and levels of propagation are determined by analyzing the performance values before and after the transformations, thus the co-existing conflict coordination strategy of multiple performances is developed. The method has been implemented in a working prototype system for supporting decision-making. And it has been demonstrated the feasible and effective through resolving the conflicts of noise, exhaust, weight and intake pressure for the screw air compressor performance design.

  12. Performances of ionizing radiation detectors required as part of a space weather service system

    Science.gov (United States)

    Cyamukungu, Mathias; Benck, Sylvie

    2012-07-01

    The selection of space radiation monitoring instruments is an essential phase in the planning of a space science mission, specifically when the data are acquired for use in the frame of a space weather service. Customer requirements for space weather services have been expressed by users and collected in reference documents like the ESA's "SSA Space Weather Segment Customer Requirement Document", among others. A review of these requirements and their implications for measurements at LEO, HEO, GTO, MEO and GEO will be presented enriched with thoroughly derived priority ranks associated with each measurable parameter. Then, the authors will describe a Global Performance Index (GPI) on various orbits for more than a dozen of currently developed or existing instruments, to conclude on an optimal selection of instruments that would be suitable to acquire the highest quality data usable for space weather applications.

  13. Application and performance requirements of hydraulic expanding technique for nuclear heat-exchanger

    International Nuclear Information System (INIS)

    Zhang Zhenhua

    2013-01-01

    The paper introduces the process and advantages of the hydraulic expanding method, and analyzes the mechanism and method of hydraulic expansion by graphical methods. Meanwhile, three performance requirements of the hydraulic expanding are described. Especially through the introduction to a typical nuclear heat exchanger tube expanding process, the importance of hydraulic expansion of tubes in design and manufacturing of nuclear heat exchanger is further illustrated. (authors)

  14. LABOUR FORCE PERCEPTIONS ABOUT THE RELATIONSHIP BETWEEN EDUCATION SYSTEM PERFORMANCES AND LABOUR MARKET REQUIREMENTS

    OpenAIRE

    Gina Cristina DIMIAN; Monica ROMAN; Laura MURESAN

    2012-01-01

    The purpose of this paper is to investigate some of the educational mismatches occurred in the Romanian labour market and to try to find solutions for a more rapid adaptation of the education system to labour market transformations. The analysis is based on a quantitative research aimed at studying employers’ opinions related to the relationship between education system performances and labour market requirements.The results show that even in a crisis period when unemployment is at high value...

  15. Synchronization control of cross-strict feedback hyperchaotic system based on cross active backstepping design

    International Nuclear Information System (INIS)

    Wang Jing; Gao Jinfeng; Ma Xikui

    2007-01-01

    This Letter presents a novel cross active backstepping design method for synchronization control of cross-strict feedback hyperchaotic system, in which the ordinary backstepping design is unavailable. The proposed control method, combining backstepping design and active control approach, extends the application of backstepping technique in chaos control. Based on this method, different combinations of controllers can be designed to meet the needs of different applications. The proposed method is applied to achieve chaos synchronization of two identical cross-strict feedback hyperchaotic systems. Also it is used to implement synchronization between cross-strict feedback hyperchaotic system and Roessler hyperchaotic system. Numerical examples illustrate the validity of the control method

  16. Defining brain-machine interface applications by matching interface performance with device requirements.

    Science.gov (United States)

    Tonet, Oliver; Marinelli, Martina; Citi, Luca; Rossini, Paolo Maria; Rossini, Luca; Megali, Giuseppe; Dario, Paolo

    2008-01-15

    Interaction with machines is mediated by human-machine interfaces (HMIs). Brain-machine interfaces (BMIs) are a particular class of HMIs and have so far been studied as a communication means for people who have little or no voluntary control of muscle activity. In this context, low-performing interfaces can be considered as prosthetic applications. On the other hand, for able-bodied users, a BMI would only be practical if conceived as an augmenting interface. In this paper, a method is introduced for pointing out effective combinations of interfaces and devices for creating real-world applications. First, devices for domotics, rehabilitation and assistive robotics, and their requirements, in terms of throughput and latency, are described. Second, HMIs are classified and their performance described, still in terms of throughput and latency. Then device requirements are matched with performance of available interfaces. Simple rehabilitation and domotics devices can be easily controlled by means of BMI technology. Prosthetic hands and wheelchairs are suitable applications but do not attain optimal interactivity. Regarding humanoid robotics, the head and the trunk can be controlled by means of BMIs, while other parts require too much throughput. Robotic arms, which have been controlled by means of cortical invasive interfaces in animal studies, could be the next frontier for non-invasive BMIs. Combining smart controllers with BMIs could improve interactivity and boost BMI applications.

  17. Clinical impact of strict criteria for selectivity and lateralization in adrenal vein sampling.

    Science.gov (United States)

    Gasparetto, Alessandro; Angle, John F; Darvishi, Pasha; Freeman, Colbey W; Norby, Ray G; Carey, Robert M

    2015-04-01

    Selectivity index (SI) and lateralization index (LI) thresholds determine the adequacy of adrenal vein sampling (AVS) and the degree of lateralization. The purpose of this study was investigate the clinical outcome of patients whose adrenal vein sampling was interpreted using "strict criteria" (SC) (SIpre-stimuli≥3, SIpost-stimuli≥5 and LIpre-stimuli≥4, LIpost-stimuli≥4). A retrospective review of 73 consecutive AVS procedures was performed and 67 were technically successful. Forty-three patients showed lateralization and underwent surgery, while 24 did not lateralize and were managed conservatively. Systolic blood pressure (SBP), diastolic blood pressure (DBP), kalemia (K(+)), and the change in number of blood pressure (BP) medications were recorded for each patient before and after AVS and potential surgery were performed. In the surgery group, BP and K(+) changed respectively from 160±5.3/100±2.0 mmHg to 127±3.3/80±1.9 (p blood pressure medications were six (14.0%) in the lateralized group and 22 (91.7%) in the non-lateralized group (p <0.001). AVS interpretation with SC leads to significant clinical improvement in both patients who underwent surgery and those managed conservatively.

  18. Energy analysis of batteries in photovoltaic systems. Part I: Performance and energy requirements

    International Nuclear Information System (INIS)

    Rydh, Carl Johan; Sanden, Bjoern A.

    2005-01-01

    The technical performance and energy requirements for production and transportation of a stand alone photovoltaic (PV)-battery system at different operating conditions are presented. Eight battery technologies are evaluated: lithium-ion (Li-ion), sodium-sulphur (NaS), nickel-cadmium (NiCd), nickel-metal hydride (NiMH), lead-acid (PbA), vanadium-redox (VRB), zinc-bromine (ZnBr) and polysulfide-bromide (PSB). In the reference case, the energy requirements for production and transport of PV-battery systems that use the different battery technologies differ by up to a factor of three. Production and transport of batteries contribute 24-70% to the energy requirements, and the PV array contributes 26-68%. The contribution from other system components is less than 10%. The contribution of transport to energy requirements is 1-9% for transportation by truck, but may be up to 73% for air transportation. The energy requirement for battery production and transport is dominant for systems based on NiCd, NiMH and PbA batteries. The energy requirements for these systems are, therefore, sensitive to changes in battery service life and gravimetric energy density. For systems with batteries with relatively low energy requirement for production and transportation (Li-ion, NaS, VRB, ZnBr, PSB), the battery charge-discharge efficiency has a larger impact. In Part II, the data presented here are used to calculate energy payback times and overall battery efficiencies of the PV-battery systems

  19. Electronic Nose Testing Procedure for the Definition of Minimum Performance Requirements for Environmental Odor Monitoring.

    Science.gov (United States)

    Eusebio, Lidia; Capelli, Laura; Sironi, Selena

    2016-09-21

    Despite initial enthusiasm towards electronic noses and their possible application in different fields, and quite a lot of promising results, several criticalities emerge from most published research studies, and, as a matter of fact, the diffusion of electronic noses in real-life applications is still very limited. In general, a first step towards large-scale-diffusion of an analysis method, is standardization. The aim of this paper is describing the experimental procedure adopted in order to evaluate electronic nose performances, with the final purpose of establishing minimum performance requirements, which is considered to be a first crucial step towards standardization of the specific case of electronic nose application for environmental odor monitoring at receptors. Based on the experimental results of the performance testing of a commercialized electronic nose type with respect to three criteria (i.e., response invariability to variable atmospheric conditions, instrumental detection limit, and odor classification accuracy), it was possible to hypothesize a logic that could be adopted for the definition of minimum performance requirements, according to the idea that these are technologically achievable.

  20. Electronic Nose Testing Procedure for the Definition of Minimum Performance Requirements for Environmental Odor Monitoring

    Directory of Open Access Journals (Sweden)

    Lidia Eusebio

    2016-09-01

    Full Text Available Despite initial enthusiasm towards electronic noses and their possible application in different fields, and quite a lot of promising results, several criticalities emerge from most published research studies, and, as a matter of fact, the diffusion of electronic noses in real-life applications is still very limited. In general, a first step towards large-scale-diffusion of an analysis method, is standardization. The aim of this paper is describing the experimental procedure adopted in order to evaluate electronic nose performances, with the final purpose of establishing minimum performance requirements, which is considered to be a first crucial step towards standardization of the specific case of electronic nose application for environmental odor monitoring at receptors. Based on the experimental results of the performance testing of a commercialized electronic nose type with respect to three criteria (i.e., response invariability to variable atmospheric conditions, instrumental detection limit, and odor classification accuracy, it was possible to hypothesize a logic that could be adopted for the definition of minimum performance requirements, according to the idea that these are technologically achievable.

  1. Strictly hyperbolic models of co-current three-phase flow withgravity

    Energy Technology Data Exchange (ETDEWEB)

    Juanes, Ruben; Patzek, Tadeusz W.

    2002-11-18

    We study the character of the equations in the traditional formulation of one-dimensional immiscible three-phase flow with gravity, in the limit of negligible capillarity. We restrict our analysis to co-current flow required for a displacement process; in cases of mixed co-current and counter-current flow, capillarity effects cannot be dropped from the formulation. The model makes use of the classical multiphase extension of Darcy's equation. It is well known that, if relative permeabilities are taken as fixed functions of saturations, the model yields regions in the saturation space where the system of equations is locally elliptic. We regard elliptic behavior as a nonphysical artifact of an incomplete formulation, and derive conditions on the relative permeabilities that ensure strict hyperbolicity of the governing equations. The key point is to acknowledge that a Darcy-type formulation is insufficient to capture all the physics of three-phase flow and that, consequently, the relative permeabilities are functionals that depend on the fluid viscosity ratio and the gravity number. The derived conditions are consistent with the type of displacements that take place in porous media. By means of an illustrative example, we show how elliptic behavior can be removed, even when using simplistic relative permeability models.

  2. The Effect of Strict Segregation on Pseudomonas aeruginosa in Cystic Fibrosis Patients

    NARCIS (Netherlands)

    van Mansfeld, Rosa; de Vrankrijker, Angelica; Brimicombe, Roland; Heijerman, Harry; Teding van Berkhout, Ferdinand; Spitoni, Cristian|info:eu-repo/dai/nl/304625957; Grave, Sanne; van der Ent, Cornelis; Wolfs, Tom; Willems, Rob; Bonten, Marc

    2016-01-01

    INTRODUCTION: Segregation of patients with cystic fibrosis (CF) was implemented to prevent chronic infection with epidemic Pseudomonas aeruginosa strains with presumed detrimental clinical effects, but its effectiveness has not been carefully evaluated. METHODS: The effect of strict segregation on

  3. Strict deformation quantization for actions of a class of symplectic lie groups

    International Nuclear Information System (INIS)

    Bieliavsky, Pierre; Massar, Marc

    2002-01-01

    We present explicit universal strict deformation quantization formulae for actions of Iwasawa subgroups AN of SN(1, n). This answers a question raised by Rieffel in [Contemp. Math. 228 (1998), 315]. (author)

  4. Strict optical orthogonal codes for purely asynchronous code-division multiple-access applications

    Science.gov (United States)

    Zhang, Jian-Guo

    1996-12-01

    Strict optical orthogonal codes are presented for purely asynchronous optical code-division multiple-access (CDMA) applications. The proposed code can strictly guarantee the peaks of its cross-correlation functions and the sidelobes of any of its autocorrelation functions to have a value of 1 in purely asynchronous data communications. The basic theory of the proposed codes is given. An experiment on optical CDMA systems is also demonstrated to verify the characteristics of the proposed code.

  5. Plant use in the medicinal practices known as "strict diets" in Chazuta valley (Peruvian Amazon).

    Science.gov (United States)

    Sanz-Biset, Jaume; Cañigueral, Salvador

    2011-09-01

    Strict diets are traditional medicinal practices where plant remedies are consumed with nearly fasting and with some sort of social seclusion. The aim of this work was to describe these practices of Chazuta and the use of plants within, as well as to analyse the possible functions of the last. The information was obtained through interviews to the 6.3% of the district rural adult population (140 individuals, 75% of which was considered Quechua). In total, 122 strict diets were recorded and 106 different plant species were reported to be used. Strict diets present a characteristic structure and plant use. The main effects reported in strict diets were antinflammatory, antiinfective, brain function alteration and depuration. Strict diets are well structured traditional medicinal practices, also with a symbolic significance in the life cycle of chazutian men. Plants used in strict diets can contribute to the main effects through antinflammation, antiinfective actions, psychoactivity and depurative related activities. The correlation between literature evidence of activity of most used plants and effects reported for the correspondent diet (i.e. in which the plant was used) are 36% for antinflammatory activity, 29% for antimicrobial activity, 18% for psychoactivity and 5% for depurative related activities. The percentages go to 77%, 64%, 73% and 32%, respectively, when literature evidences on related taxa are also considered. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  6. Position requirements for space station personnel and linkages to portable microcomputer performance assessment

    Science.gov (United States)

    Jeanneret, P. R.

    1988-01-01

    The development and use of a menu of performance tests that can be self-administered on a portable microcomputer are investigated. In order to identify, develop, or otherwise select the relevant human capabilities/attributes to measure and hence include in the performance battery, it is essential that an analysis be conducted of the jobs or functions that will be performed throughout a space shuttle mission. The primary job analysis instrument, the Position Analysis Questionnaire (PAQ), is discussed in detail so the reader will have sufficient background for understanding the application of the instrument to the various work activities included within the scope of the study, and the derivation of the human requirements (abilities/attributes) from the PAQ analyses. The research methodology is described and includes the procedures used for gathering the PAQ data. The results are presented in detail with specific emphasis on identifying critical requirements that can be measured with a portable computerized assessment battery. A discussion of the results is given with implications for future research.

  7. Do admission requirements to dentistry predicts the academic performance over the first year?

    Directory of Open Access Journals (Sweden)

    Alejandra Medina

    2012-07-01

    Full Text Available Introduction: Having clear which are de predictors of academic development, the selection of students that enter University, can be improved, assuring that they are in possession of the competitions that guaranty a good performance. Objectives: To determine the predictive capacity of the entering requirements and the PSU process, for the academic performance of the students of first year in the Odontology career. Material and Method: Descriptive observational study, of transversal cut with students that went through first year between 2004 and 2008. The entering schedules of de Unity of Admission and Academic Student Register (UDARAE, were checked, obtaining information about the gender, entering year, average notes of senior year (NEM, selection score (PSU-SEL and the score of the language (PSU-L, math (PSU-M and science (PSU-C exams. For the academic performance the schedule of marks of the Register and Faculty Control Office was checked. Results: The bigger percentage of contribution to the explanation of the academic performance corresponded to the NEM average, with 10%, then the PSU-C with 5.6%. The PSU-L and PSU-M, had a 0% of contribution and the PSUSEL a 23.4%. Conclusions: The most strong variable that can be associated with the academic performance is the NEM average, followed by the PSU-C. The PSU-L and the PSU-M presented a void predictive capacity. The PSU process presented a limited predictive capacity.

  8. Sequestration Coating Performance Requirements for Mitigation of Contamination from a Radiological Dispersion Device

    International Nuclear Information System (INIS)

    Drake, J.

    2009-01-01

    Immediate action would be necessary to minimize the effects of a radiological 'dirty bomb' detonation in a major city. After a dirty bomb has been detonated, vehicular and pedestrian traffic, as well as weather effects, would increase the spread of loose contamination, making control and recovery more difficult and costly. While contaminant migration and chemical binding into surface materials can be relatively rapid, the immediate treatment of surfaces with large quantities of an appropriate compound could alleviate much of the difficulty in decontamination. The EPA's National Homeland Security Research Center (NHSRC), in collaboration with ASTM International, is currently developing performance standards for materials which could be applied to exterior surfaces contaminated by an RDD to mitigate the spread and migration of radioactive contamination. These performance standards are being promulgated via an ASTM Standard Specification to be published by ASTM International. Test methods will be developed to determine if candidate coatings meet the performance requirements stipulated in the ASTM performance standard. These test methods will be adapted from existing standard methods, or will be devised through laboratory research. The final set of test methods will be codified in an ASTM or other standard test method. The principal market for products described in the ASTM performance standard would be federal, state and local government emergency responders and response planners, decontamination service providers and those whose interests include protection and recovery of real estate potentially at risk from radiological terrorism. (authors)

  9. Base technology development enhances state-of-the-art in meeting performance requirements

    International Nuclear Information System (INIS)

    Freedman, J.M.; Allen, G.C. Jr.; Luna, R.E.

    1987-01-01

    Sandia National Laboratories (SNL) has responsibility to the United States Department of Energy (DOE) for baseline technology to support the design of radioactive material transportation packages. To fulfill this responsibility, SNL works with industry, government agencies, and national laboratories to identify and develop state-of-the-art technology required to design and test safe, cost-effective radioactive materials packages. Principal elements of the base technology program include: 1) analysis techniques, 2) testing, 3) subsystem and component development, 4) packaging systems development support, and 5) technical support for policy development. These program elements support a systems approach for meeting performance requirements and assure that there is a sound underlying technical basis for both transportation packaging design and associated policy decisions. Highlights from the base technology program included in this paper are testing, design and analysis methods, advanced materials, risk assessment and logistics models, and transportation package support

  10. Base technology development enhances state-of-the-art in meeting performance requirements

    International Nuclear Information System (INIS)

    Freedman, J.M.; Allen, G.C. Jr.; Luna, R.E.

    1987-01-01

    Sandia National Laboratories (SNL) has responsibility to the United States Department of Energy (DOE) for baseline technology to support the design of radioactive material transportation packages. To fulfill this responsibility, SNL works with industry, government agencies, and national laboratories to identify and develop state-of-the-art technology required to design and test safe, cost-effective radioactive materials packages. Principal elements of the base technology program include: (1) analysis techniques; (2) testing; (3) subsystem and component development; (4) packaging systems development support; and (5) technical support for policy development. These program elements support a systems approach for meeting performance requirements and assure that there is a sound underlying technical basis for both transportation packaging design and associated policy decisions. Highlights from the base technology program included in this paper are testing, design and analysis methods, advanced materials, risk assessment and logistics models, and transportation package support

  11. Immediate effect of instrumentation on the subgingival microflora in deep inflamed pockets under strict plaque control.

    Science.gov (United States)

    Rhemrev, G E; Timmerman, M F; Veldkamp, I; Van Winkelhoff, A J; Van der Velden, U

    2006-01-01

    To investigate (1) reduction in the number of microorganisms obtained directly after subgingival instrumentation, (2) rate of bacterial re-colonization during 2 weeks, under supragingival plaque-free conditions. Effects of subgingival instrumentation were measured at one deep pocket in 22 patients (11 smokers and 11 non-smokers). Immediately after initial therapy, experimental sites, under strict plaque control, were instrumented subgingivally. Microbiological evaluation was performed at pre-instrumentation, immediate post-instrumentation and 1 and 2 weeks post-instrumentation. Mean total anaerobic colony forming units (CFUs) dropped from 3.9 x 10(6) before to 0.09 x 10(6) immediately following instrumentation. Significant reductions were found for Tannerella forsythia, Micromonas micros, Fusobacterium nucleatum and spirochetes. Significant reductions were not observed for Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia and Campylobacter rectus. Except for spirochetes, no reduction in prevalence of specific periodontal bacteria was found immediately after instrumentation. During follow-up, mean total CFU tended to increase. Prevalence of periodontal bacteria further reduced. No effect of smoking was found. Results indicate that subgingival mechanical cleaning in itself, has a limited effect, in actually removing bacteria. The subsequent reduction in prevalence of specific periodontal bacteria shows that it is apparently difficult for these species to survive in treated pockets.

  12. Magnetic resonance imaging quantitation of changes in muscle volume during 7 days of strict bed rest.

    Science.gov (United States)

    Ferrando, A A; Stuart, C A; Brunder, D G; Hillman, G R

    1995-10-01

    Prolonged bed rest results in a loss of leg lean body mass. Previous studies using bed rest as a model for microgravity have shown decreases in leg mass after 12 and 14 d, 5 and 17 wk. As magnetic resonance imaging (MRI) can provide a precise and non-invasive means of determining muscle volume, we sought to determine if changes in leg muscle volume could be detected in bed rest periods as short as 7 d. Five young, healthy, male volunteers were subjected to 7 d of absolute bed rest. Each subject underwent MRI quantitation of segmental muscle volumes of the calves and thighs before and after bed rest. Eleven (calf) and nine (thigh) contiguous 1-cm thick transaxial images were generated over prescribed regions using a Technicare MRI imager with a 0.6T superconducting magnet and body coil. Image processing was performed using a generalized 8-bit medical image analysis package developed at University of Texas Medical Branch. Images were analyzed for muscle and non-muscle volumes (including fat, blood vessel, and bone marrow volumes). The MRI quantitation demonstrated bed rest-induced significant decreases in segmental thigh muscle (approximately 3.0%, p image analysis of MRI images provides a sensitive tool capable of detecting leg volume changes of as little as 3.0% over a 7-d period of strict bed rest.

  13. Aerated lagooning of agro-industrial wastewater: depuration performance and energy requirements

    Directory of Open Access Journals (Sweden)

    Serafina Andiloro

    2013-09-01

    Full Text Available Intensive depuration plants have often shown low reliability and economic sustainability, when utilised for agro-industrial wastewater treatment, due to the particular wastewater properties: high organic load and essential oil concentrations, acidity, nutrient scarcity and qualitative-quantitative variability of effluents. Aerated lagooning systems represent a suitable alternative, because they are able to assure good reliability and low energy requirements, avoiding the drawbacks shown by the intensive depuration plants. In order to optimize performance of the lagooning systems, particularly in terms of energy requirements, depuration processes of aerobic-anaerobic aerated lagoons were investigated, both at full- and laboratory-scale. Citrus processing wastewater were subject to bubble aeration with low flow rates and limited time; the removal rate of organic load was evaluated and energy requirements of different depuration schemes were compared. The experimental investigations in full-scale aerated lagoons showed a low energy supply (0.21-0.59 kWh per kg of COD (Chemical Oxygen Demand removed with an average value of 0.45 kWh kgCOD –1, an adequate equalisation capability and constantly good depurative performance also with high concentrations of essential oil (500-1000 ppm. The experimental investigations in lab-scale aerated tanks under controlled conditions indicated the possibility of decreasing energy requirements (down to 0.16 kWh kgCOD –1 by reducing aeration power (down to 0.6 W m–3 and limiting aeration time to night 12 hours only, when energy price is lower. In spite of the low aeration, the COD removal rates were on the average six-fold higher compared to the anaerobic tank. Other outcomes indicated an ability of the spontaneous microflora to adapt to high concentrations of essential oils, which however did not provide an increase of the removal rate of the organic load in the experimented scheme.

  14. Job Language Performance Requirements for Pre-BT Extended English Language Course.

    Science.gov (United States)

    1982-07-01

    I AD-A117 8󈧮 DEFENSErLANGUAGE INST LACKLAND AFB TX ENGLISH LANGUA--ETC FIG 5/iS JOB LANGUAGE PERFORMANCE REQUIREMENTS FOR PRE-BT EXTENDED ENGLI ...muzzle. A2-7 VERBS 1. VERB TENSES Make sure you clearly understand the task you are to teach . --You will be tested. --If they elect to take it, they must...mask. A2-10 LIST OF LEXICAL AND STRUCTURAL ITEMS FOR ENGLISH LANGUAGE STRUCTURES Sentences: A. Declarative statement B. Interrogative question 1. wh

  15. High Performance Computing and Storage Requirements for Nuclear Physics: Target 2017

    Energy Technology Data Exchange (ETDEWEB)

    Gerber, Richard [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Wasserman, Harvey [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2014-04-30

    In April 2014, NERSC, ASCR, and the DOE Office of Nuclear Physics (NP) held a review to characterize high performance computing (HPC) and storage requirements for NP research through 2017. This review is the 12th in a series of reviews held by NERSC and Office of Science program offices that began in 2009. It is the second for NP, and the final in the second round of reviews that covered the six Office of Science program offices. This report is the result of that review

  16. Dose-homogeneity Driven Beam Delivery System Performance Requirements for MedAustron

    CERN Document Server

    Palm, M; Moser, F; Benedikt, M

    2011-01-01

    MedAustron [1], the Austrian hadron therapy center is currently under construction. Irradiation will be performed using active scanning with proton and carbon ion pencil beams. Major beam delivery system contributors to dose heterogeneities are evaluated: beam position, beam size and spot weight errors. Their individual and combined effect on the dose distribution is quantified, using semianalytical models of lateral beam spread in the nozzle and target and depth-dose curves for protons and carbon ions. Deduced requirements on critical parts of the beam delivery system are presented. Preventive and active methods to suppress the impact of beam delivery inaccuracies are proposed.

  17. Performance requirements of an inertial-fusion-energy source for hydrogen production

    International Nuclear Information System (INIS)

    Hovingh, J.

    1983-01-01

    Performance of an inertial fusion system for the production of hydrogen is compared to a tandem-mirror-system hydrogen producer. Both systems use the General Atomic sulfur-iodine hydrogen-production cycle and produce no net electric power to the grid. An ICF-driven hydrogen producer will have higher system gains and lower electrical-consumption ratios than the design point for the tandem-mirror system if the inertial-fusion-energy gain eta Q > 8.8. For the ICF system to have a higher hydrogen production rate per unit fusion power than the tandem-mirror system requires that eta Q > 17. These can be achieved utilizing realistic laser and pellet performances

  18. Summary of Requirements for Sewage Sludge Incinerators (SSI): New Source Performance Standards (NSPS) and Emission Guidelines (EG)

    Science.gov (United States)

    This November 2011 document summarizes the various requirements of the sewage sludge incinerators (SSI) new source performance standards (NSPS) and emission guidelines (EG), broken down into compliance categories.

  19. Determination of Orientation and Practice Requirements When Using an Obstacle Course for Mobility Performance Assessment.

    Science.gov (United States)

    Karakolis, Thomas; Sinclair, Brittany A; Kelly, Alison; Terhaar, Phil; Bossi, Linda L M

    2017-06-01

    Determine effect of orientation (introduction and familiarization) and practice (repeated performance) on human performance under various load conditions as assessed by an obstacle course. Obstacle courses are commonly used as screening tools by military, police, and firefighters or to assess human capabilities and the effect of wearing personal protective equipment (PPE) and other occupationally necessary equipment on mobility task performance. Unfortunately, little is formally documented about the effect of orientation and practice on performance outcomes of obstacle or mobility courses being used. Forty-eight participants were recruited from the Canadian Army Infantry and Combat Engineer population. Participants either received regular or extensive orientation of the course before completing it. Following orientation, participants completed the course five consecutive times while wearing their PPE with full fighting order (FFO) and five consecutive times while wearing no PPE and non-FFO across a five-day period (maximum two runs per day), with ensemble presentation order counterbalanced. Total course completion time and individual obstacle completion times were measured for each run of the course. While wearing FFO, participants continued to decrease the time required for completing the course; however, while wearing non-FFO, time to course completion did not significantly change over the five runs. There were no differences in course completion times for the regular and extensive course orientation groups. Considerations required to mitigate orientation and practicing effects can differ depending on type or complexity of load condition. While wearing FFO, practicing effects can introduce undesired confounding factors into data collection. Any practice runs on an obstacle course prior to its use as an assessment tool should focus on the loaded (e.g., FFO) condition because improvement on loaded runs is likely transferred to unloaded, but this does not apply in

  20. Sleep-related offline improvements in gross motor task performance occur under free recall requirements

    Directory of Open Access Journals (Sweden)

    Andreas eMalangre

    2016-03-01

    Full Text Available Nocturnal sleep effects on memory consolidation following gross motor sequence learning were examined using a complex arm movement task. This task required participants to produce non-regular spatial patterns in the horizontal plane by successively fitting a small peg into different target-holes on an electronic pegboard. The respective reaching movements typically differed in amplitude and direction. Targets were visualized prior to each transport movement on a computer screen. With this task we tested 18 subjects (22.6 +/- 1.9 years; 8 female using a between-subjects design. Participants initially learned a 10-element arm movement sequence either in the morning or in the evening. Performance was retested under free recall requirements 15 minutes post training, as well as 12 hrs and 24 hrs later. Thus each group was provided with one sleep-filled and one wake retention interval. Dependent variables were error rate (number of erroneous sequences and average sequence execution time (correct sequences only. Performance improved during acquisition. Error rate remained stable across retention. Sequence execution time (inverse to execution speed significantly decreased again during the sleep-filled retention intervals, but remained stable during the respective wake intervals. These results corroborate recent findings on sleep-related enhancement consolidation in ecological valid, complex gross motor tasks. At the same time they suggest this effect to be truly memory-based and independent from repeated access to extrinsic sequence information during retests.

  1. Minimum Performance Requirements for Microbial Fuel Cells to Achieve Energy-Neutral Wastewater Treatment

    Directory of Open Access Journals (Sweden)

    Zachary A. Stoll

    2018-02-01

    Full Text Available Microbial fuel cells (MFCs have recently achieved energy-positive wastewater treatment at pilot scale. Despite these achievements, there is still a limited understanding as to whether all wastewaters contain sufficient amounts of energy and, if so, whether MFCs can capture a sufficient amount of energy to offset electrical energy requirements in the wastewater treatment process. Currently, there are no tools or methods available that can determine whether an MFC can be energy-neutral a priori. To address this, we derived a simple relationship by setting the electrical energy requirements of a wastewater treatment facility equal to the net energy output of the MFC, such that the resulting expression describes the minimum chemical oxygen demand (COD removal needed to achieve energy-neutral treatment. The resulting equation is simply a function of electrical energy requirements, Coulombic Efficiency, and cell voltage. This work provides the first ever quantitative method for determining if the MFCs are feasible to achieve energy-neutral treatment for a given wastewater and what level of performance is needed.

  2. Virtual environment to quantify the influence of colour stimuli on the performance of tasks requiring attention.

    Science.gov (United States)

    Silva, Alessandro P; Frère, Annie F

    2011-08-19

    Recent studies indicate that the blue-yellow colour discrimination is impaired in ADHD individuals. However, the relationship between colour and performance has not been investigated. This paper describes the development and the testing of a virtual environment that is capable to quantify the influence of red-green versus blue-yellow colour stimuli on the performance of people in a fun and interactive way, being appropriate for the target audience. An interactive computer game based on virtual reality was developed to evaluate the performance of the players.The game's storyline was based on the story of an old pirate who runs across islands and dangerous seas in search of a lost treasure. Within the game, the player must find and interpret the hints scattered in different scenarios. Two versions of this game were implemented. In the first, hints and information boards were painted using red and green colours. In the second version, these objects were painted using blue and yellow colours. For modelling, texturing, and animating virtual characters and objects the three-dimensional computer graphics tool Blender 3D was used. The textures were created with the GIMP editor to provide visual effects increasing the realism and immersion of the players. The games were tested on 20 non-ADHD volunteers who were divided into two subgroups (A1 and A2) and 20 volunteers with ADHD who were divided into subgroups B1 and B2. Subgroups A1 and B1 used the first version of the game with the hints painted in green-red colors, and subgroups A2 and B2 the second version using the same hints now painted in blue-yellow. The time spent to complete each task of the game was measured. Data analyzed with ANOVA two-way and posthoc TUKEY LSD showed that the use of blue/yellow instead of green/red colors decreased the game performance of all participants. However, a greater decrease in performance could be observed with ADHD participants where tasks, that require attention, were most affected

  3. Virtual environment to quantify the influence of colour stimuli on the performance of tasks requiring attention

    Directory of Open Access Journals (Sweden)

    Frère Annie F

    2011-08-01

    where tasks, that require attention, were most affected. Conclusions The game proved to be a user-friendly tool capable to detect and quantify the influence of color on the performance of people executing tasks that require attention and showed to be attractive for people with ADHD.

  4. L-Band System Engineering - Concepts of Use, Systems Performance Requirements, and Architecture

    Science.gov (United States)

    Henriksen, Stephen; Zelkin, Natalie

    2011-01-01

    This document is being provided as part of ITT s NASA Glenn Research Center Aerospace Communication Systems Technical Support (ACSTS) contract NNC05CA85C, Task 7: New ATM Requirements-Future Communications, C-band and L-band Communications Standard Development. Task 7 was motivated by the five year technology assessment performed for the Federal Aviation Administration (FAA) under the joint FAA-EUROCONTROL cooperative research Action Plan (AP-17), also known as the Future Communications Study (FCS). It was based on direction provided by the FAA project-level agreement (PLA FY09_G1M.02-02v1) for "New ATM Requirements-Future Communications." Task 7 was separated into two distinct subtasks, each aligned with specific work elements and deliverable items. Subtask 7-1 addressed C-band airport surface data communications standards development, systems engineering, test bed development, and tests/demonstrations to establish operational capability for what is now referred to as the Aeronautical Mobile Airport Communications System (AeroMACS). Subtask 7-2, which is the subject of this report, focused on preliminary systems engineering and support of joint FAA/EUROCONTROL development and evaluation of a future L-band (960 to 1164 MHz) air/ground (A/G) communication system known as the L-band digital aeronautical communications system (L-DACS), which was defined during the FCS. The proposed L-DACS will be capable of providing ATM services in continental airspace in the 2020+ timeframe. Subtask 7-2 was performed in two phases. Phase I featured development of Concepts of Use, high level functional analyses, performance of initial L-band system safety and security risk assessments, and development of high level requirements and architectures. It also included the aforementioned support of joint L-DACS development and evaluation, including inputs to L-DACS design specifications. Phase II provided a refinement of the systems engineering activities performed during Phase I, along

  5. Integration plan required by performance agreement SM 7.2.1

    International Nuclear Information System (INIS)

    Diediker, L.P.

    1997-01-01

    Fluor Daniel Hanford, Inc. and its major subcontractors are in agreement that environmental monitoring performed under the Project Hanford Management Contract is to be done in accordance with a single, integrated program. The purpose of this Integration Plan for Environmental Monitoring is to document the policies, systems, and processes being put in place to meet one key objective: manage and integrate a technically competent, multi-media ambient environmental monitoring program, in an efficient, cost effective manner. Fluor Daniel Hanford, Inc. and its major subcontractors also commit to conducting business in a manner consistent with the International Standards Organization 14000 Environmental Management System concepts. Because the integration of sitewide groundwater monitoring activities is managed by the Environmental Restoration Contractor, groundwater monitoring it is outside the scope of this document. Therefore, for the purpose of this Integration Plan for Environmental Monitoring, the Integrated Environmental Monitoring Program is defined as applicable to all environmental media except groundwater. This document provides recommendations on future activities to better integrate the overall environmental monitoring program, with emphasis on the near-field program. In addition, included is the Fluor Daniel Hanford, Inc. team review of the environmental monitoring activities on the Hanford Site, with concurrence of Pacific Northwest National Laboratory and Bechtel Hanford, Inc. (The narrative provided later in the Discussion Section describes the review and consideration given to each topic.) This document was developed to meet the requirements of the Project Hanford Management Contract performance agreement (SM7.2) and the tenets of the U.S. Department of Energy's Effluent and Environmental Monitoring Planning Process. This Plan is prepared for the U.S. Department of Energy, Richland Operations Office, Environmental Assurance, Permits, and Policy Division

  6. Actions of a separately strict cpo-monoid on pointed directed complete posets

    Directory of Open Access Journals (Sweden)

    Halimeh Moghbeli Damaneh

    2015-07-01

    Full Text Available ‎ In the present article‎, ‎we study some categorical properties of the category {$bf‎ Cpo_{Sep}$-$S$} of all {separately strict $S$-cpo's}; cpo's equipped with‎ a compatible right action of a separately strict cpo-monoid $S$ which is‎ strict continuous in each component‎. ‎In particular‎, we show that this category is reflective and coreflective in the‎ category of $S$-cpo's‎, ‎find the free and cofree functors‎, characterize products and coproducts‎. ‎Furthermore‎, ‎epimorphisms and‎  monomorphisms in {$bf Cpo_{Sep}$-$S$} are studied‎, ‎and show that‎ {$bf Cpo_{Sep}$-$S$} is not cartesian closed‎.

  7. LABOUR FORCE PERCEPTIONS ABOUT THE RELATIONSHIP BETWEEN EDUCATION SYSTEM PERFORMANCES AND LABOUR MARKET REQUIREMENTS

    Directory of Open Access Journals (Sweden)

    Gina Cristina DIMIAN

    2012-07-01

    Full Text Available The purpose of this paper is to investigate some of the educational mismatches occurred in the Romanian labour market and to try to find solutions for a more rapid adaptation of the education system to labour market transformations. The analysis is based on a quantitative research aimed at studying employers’ opinions related to the relationship between education system performances and labour market requirements.The results show that even in a crisis period when unemployment is at high values, employers have difficulties in fi nding appropriate qualifications for some jobs, or the right candidate for the vacancies. Even current employees lack some important abilities or skills such us: motivation, loyalty or responsibility.

  8. Saccharomyces cerevisiae vineyard strains have different nitrogen requirements that affect their fermentation performances.

    Science.gov (United States)

    Lemos Junior, W J F; Viel, A; Bovo, B; Carlot, M; Giacomini, A; Corich, V

    2017-11-01

    In this work the fermentation performances of seven vineyard strains, together with the industrial strain EC1118, have been investigated at three differing yeast assimilable nitrogen (YAN) concentrations (300 mg N l -1 , 150 mg N l -1 and 70 mg N l -1 ) in synthetic musts. The results indicated that the response to different nitrogen levels is strain dependent. Most of the strains showed a dramatic decrease of the fermentation at 70 mg N l -1 but no significant differences in CO 2 production were found when fermentations at 300 mg N l -1 and 150 mg N l -1 were compared. Only one among the vineyard strains showed a decrease of the fermentation when 150 mg N l -1 were present in the must. These results contribute to shed light on strain nitrogen requirements and offer new perspectives to manage the fermentation process during winemaking. Selected vineyard Saccharomyces cerevisiae strains can improve the quality and the complexity of local wines. Wine quality is also influenced by nitrogen availability that modulates yeast fermentation activity. In this work, yeast nitrogen assimilation was evaluated to clarify the nitrogen requirements of vineyard strains. Most of the strains needed high nitrogen levels to express the best fermentation performances. The results obtained indicate the critical nitrogen levels. When the nitrogen concentration was above the critical level, the fermentation process increased, but if the level of nitrogen was further increased no effect on the fermentation was found. © 2017 The Society for Applied Microbiology.

  9. A modal H∞-norm-based performance requirement for damage-tolerant active controller design

    Science.gov (United States)

    Genari, Helói F. G.; Mechbal, Nazih; Coffignal, Gérard; Nóbrega, Eurípedes G. O.

    2017-04-01

    Damage-tolerant active control (DTAC) is a recent research area that encompasses control design methodologies resulting from the application of fault-tolerant control methods to vibration control of structures subject to damage. The possibility of damage occurrence is not usually considered in the active vibration control design requirements. Damage changes the structure dynamics, which may produce unexpected modal behavior of the closed-loop system, usually not anticipated by the controller design approaches. A modal H∞ norm and a respective robust controller design framework were recently introduced, and this method is here extended to face a new DTAC strategy implementation. Considering that damage affects each vibration mode differently, this paper adopts the modal H∞ norm to include damage as a design requirement. The basic idea is to create an appropriate energy distribution over the frequency range of interest and respective vibration modes, guaranteeing robustness, damage tolerance, and adequate overall performance, taking into account that it is common to have previous knowledge of the structure regions where damage may occur during its operational life. For this purpose, a structural health monitoring technique is applied to evaluate modal modifications caused by damage. This information is used to create modal weighing matrices, conducting to the modal H∞ controller design. Finite element models are adopted for a case study structure, including different damage severities, in order to validate the proposed control strategy. Results show the effectiveness of the proposed methodology with respect to damage tolerance.

  10. Bearings for high performance requirements in two-stroke and four-stroke diesel engines

    Energy Technology Data Exchange (ETDEWEB)

    Ederer, U.G.

    1983-11-01

    Most measures to reduce fuel consumption in diesel engines lead, directly or indirectly, to more severe operating conditions for the engine bearings. In ever more instances the bearings become the components which limit useful engine life and the time between overhauls. Bearings with improved performance characteristics are required. During recent years, Miba Gleitlager AG has developed several solutions to meet these requirements. They consist of either material improvements, such as a cast white metal (SnSb 12Cu 3 NiCd) with higher fatigue strength, or an electroplated overlay (PbSn 18 Cu) with improved fatigue and wear resistance. New design solutions found included the steel-Al Sn 6-WM 85 bearing for two-stroke engines, the steel-Al Sn 6 PbSn 18 Cu bearing applied to two-stroke crosshead bearings, the steel-AlZn 4,5 PbSn 18 Cu bearing for high bearing loads in four-stroke engines, and the Miba-Rillenlager with its radically new running-surface structure for extreme load and wear conditions. The application potential of these bearings and the operating experience with them are discussed in this article.

  11. The Physics of Hard Spheres Experiment on MSL-1: Required Measurements and Instrument Performance

    Science.gov (United States)

    Doherty, Michael P.; Lant, Christian T.; Ling, Jerri S.

    1998-01-01

    The Physics of HArd Spheres Experiment (PHaSE), one of NASA Lewis Research Center's first major light scattering experiments for microgravity research on complex fluids, flew on board the Space Shuttle's Microgravity Science Laboratory (MSL-1) in 1997. Using colloidal systems of various concentrations of micron-sized plastic spheres in a refractive index-matching fluid as test samples, illuminated by laser light during and after crystallization, investigations were conducted to measure the nucleation and growth rate of colloidal crystals as well as the structure, rheology, and dynamics of the equilibrium crystal. Together, these measurements support an enhanced understanding of the nature of the liquid-to-solid transition. Achievement of the science objectives required an accurate experimental determination of eight fundamental properties for the hard sphere colloidal samples. The instrument design met almost all of the original measurement requirements, but with compromise on the number of samples on which data were taken. The instrument performs 2-D Bragg and low angle scattering from 0.4 deg. to 60 deg., dynamic and single-channel static scattering from 10 deg. to 170 deg., rheology using fiber optics, and white light imaging of the sample. As a result, PHaSE provided a timely microgravity demonstration of critical light scattering measurement techniques and hardware concepts, while generating data already showing promise of interesting new scientific findings in the field of condensed matter physics.

  12. Selection of the battery pack parameters for an electric vehicle based on performance requirements

    Science.gov (United States)

    Koniak, M.; Czerepicki, A.

    2017-06-01

    Each type of vehicle has specific power requirements. Some require a rapid charging, other make long distances between charges, but a common feature is the longest battery life time. Additionally, the battery is influenced by factors such as temperature, depth of discharge and the operation current. The article contain the parameters of chemical cells that should be taken into account during the design of the battery for a specific application. This is particularly important because the batteries are not properly matched and can wear prematurely and cause an additional costs. The method of selecting the correct cell type should take previously discussed features and operating characteristics of the vehicle into account. The authors present methods of obtaining such characteristics along with their assessment and examples. Also there has been described an example of the battery parameters selection based on design assumptions of the vehicle and the expected performance characteristics. Selecting proper battery operating parameters is important due to its impact on the economic result of investments in electric vehicles. For example, for some Li-Ion technologies, the earlier worn out of batteries in a fleet of cruise boats or buses having estimated lifetime of 10 years is not acceptable, because this will cause substantial financial losses for the owner of the rolling stock. The presented method of choosing the right cell technology in the selected application, can be the basis for making the decision on future battery technical parameters.

  13. The photon is no strict particle and nonlocality is far from being proven

    Energy Technology Data Exchange (ETDEWEB)

    Greulich, Karl Otto [Fritz Lipmann Institut, Jena (Germany)

    2010-07-01

    Two aspects of philosophical discussions on physics are the wave particle dualism and non locality including entanglement. However the strict particle aspect of the photon, in the common sense view, has never been proven. The accumulation time argument, the only experimental verification of a strictly particle like photon, has so far not yet been satisfied. Also, experiments thought to prove nonlocality have loophole which have so far not yet been safely closed, and now an even more serious loophole emerges. Thus, also nonlocality cannot be seen as proven. This demands some fine tuning of philosophical discussions on critical experiments in physics.

  14. More strictly protected areas are not necessarily more protective: evidence from Bolivia, Costa Rica, Indonesia, and Thailand

    International Nuclear Information System (INIS)

    Ferraro, Paul J; Hanauer, Merlin M; Miteva, Daniela A; Pattanayak, Subhrendu K; Canavire-Bacarreza, Gustavo Javier; Sims, Katharine R E

    2013-01-01

    National parks and other protected areas are at the forefront of global efforts to protect biodiversity and ecosystem services. However, not all protection is equal. Some areas are assigned strict legal protection that permits few extractive human uses. Other protected area designations permit a wider range of uses. Whether strictly protected areas are more effective in achieving environmental objectives is an empirical question: although strictly protected areas legally permit less anthropogenic disturbance, the social conflicts associated with assigning strict protection may lead politicians to assign strict protection to less-threatened areas and may lead citizens or enforcement agents to ignore the strict legal restrictions. We contrast the impacts of strictly and less strictly protected areas in four countries using IUCN designations to measure de jure strictness, data on deforestation to measure outcomes, and a quasi-experimental design to estimate impacts. On average, stricter protection reduced deforestation rates more than less strict protection, but the additional impact was not always large and sometimes arose because of where stricter protection was assigned rather than regulatory strictness per se. We also show that, in protected area studies contrasting y management regimes, there are y 2 policy-relevant impacts, rather than only y, as earlier studies have implied. (letter)

  15. 42 CFR 493.53 - Notification requirements for laboratories issued a certificate for provider-performed microscopy...

    Science.gov (United States)

    2010-10-01

    ... certificate for provider-performed microscopy (PPM) procedures. 493.53 Section 493.53 Public Health CENTERS... CERTIFICATION LABORATORY REQUIREMENTS Registration Certificate, Certificate for Provider-performed Microscopy... certificate for provider-performed microscopy (PPM) procedures. Laboratories issued a certificate for PPM...

  16. Strict Monotonicity and Unique Continuation for the Third-Order Spectrum of Biharmonic Operator

    Directory of Open Access Journals (Sweden)

    Khalil Ben Haddouch

    2012-01-01

    Full Text Available We will study the spectrum for the biharmonic operator involving the laplacian and the gradient of the laplacian with weight, which we call third-order spectrum. We will show that the strict monotonicity of the eigenvalues of the operator , where , holds if some unique continuation property is satisfied by the corresponding eigenfunctions.

  17. "Let the Master Respond": Should Schools Be Strictly Liable When Employees Sexually Abuse Children?

    Science.gov (United States)

    Fossey, Richard; DeMitchell, Todd

    Although sexual abuse against children is a problem in the public schools, school officials have generally not acted aggressively to stop it. This paper argues for a strict liability standard--the assessment of liability without fault--against a school district in cases of student sexual abuse by a school employee. Part 1 explores the principle of…

  18. Detection of low numbers of microplastics in North Sea fish using strict quality assurance criteria

    NARCIS (Netherlands)

    Hermsen, E.; Pompe, R.; Besseling, E.; Koelmans, A.A.

    2017-01-01

    We investigated 400 individual fish of four North Sea species: Atlantic Herring, Sprat, Common Dab, and Whiting on ingestion of > 20 μm microplastic. Strict quality assurance criteria were followed in order to control contamination during the study. Two plastic particles were found in only 1 (a

  19. History, administration, goals, values, and long-term data of Russia's strictly protected scientific nature reserves

    Science.gov (United States)

    Martin A. Spetich; Anna E. Kvashnina; Y.D. Nukhimovskya; Olin E. Jr. Rhodes

    2009-01-01

    One of the most comprehensive attempts at biodiversity conservation in Russia and the former Soviet Union has been the establishment of an extensive network of protected natural areas. Among all types of protected areas in Russia, zapovedniks (strictly protected scientific preserve) have been the most effective in protecting biodiversity at the ecosystem scale. Russia...

  20. The Preventive Effect of Strict Gun Control Laws on Suicide and Homicide.

    Science.gov (United States)

    Lester, David; Murrell, Mary E.

    1982-01-01

    Examined state gun control laws and used a multidimensional scaling technique to study the relationship of strictness and death rates. Results showed states with stricter laws had lower suicide rates by firearms but higher rates by other means. No effect on homicide was found. (JAC)

  1. Adaptive terminal sliding mode control for hypersonic flight vehicles with strictly lower convex function based nonlinear disturbance observer.

    Science.gov (United States)

    Wu, Yun-Jie; Zuo, Jing-Xing; Sun, Liang-Hua

    2017-11-01

    In this paper, the altitude and velocity tracking control of a generic hypersonic flight vehicle (HFV) is considered. A novel adaptive terminal sliding mode controller (ATSMC) with strictly lower convex function based nonlinear disturbance observer (SDOB) is proposed for the longitudinal dynamics of HFV in presence of both parametric uncertainties and external disturbances. First, for the sake of enhancing the anti-interference capability, SDOB is presented to estimate and compensate the equivalent disturbances by introducing a strictly lower convex function. Next, the SDOB based ATSMC (SDOB-ATSMC) is proposed to guarantee the system outputs track the reference trajectory. Then, stability of the proposed control scheme is analyzed by the Lyapunov function method. Compared with other HFV control approaches, key novelties of SDOB-ATSMC are that a novel SDOB is proposed and drawn into the (virtual) control laws to compensate the disturbances and that several adaptive laws are used to deal with the differential explosion problem. Finally, it is illustrated by the simulation results that the new method exhibits an excellent robustness and a better disturbance rejection performance than the convention approach. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

  2. Digital Image Display Station Performance Requirements Based on Physician Experience with a Prototype System

    Science.gov (United States)

    Fisher, Paul D.; Grover, Brent; Brauer, Gerhard W.; Ritchie, Gordon W.

    1989-05-01

    The authors report on observations of, and interviews with, physicians using a prototype digital image display and reporting station. While the users generally agree that image quality is clinically satisfactory they are unanimous in their opinion that improvements in the man-machine interface are required before case review by this mechanism is clinically acceptable in a production environment. A model image and information user interface is presented. It was developed in answer to the needs of radiologists and referring physicians operating in the imaging department of a community acute care facility. In such an environment images and related information must be communicated quickly and often simultaneously to different parts of the department and hospital. The user interface to the management system and the management system itself must address the varied functions and the needs of both the medical and clerical staff that perform them. Image enhancement processes, for example, must be restricted to those which quickly provide significantly more perceivable diagnostic information. Little used processes that may occupy significant portions of the display and the console's computing power must be trimmed or eliminated.

  3. Performance of methods for estimation of table beet water requirement in Alagoas

    Directory of Open Access Journals (Sweden)

    Daniella P. dos Santos

    Full Text Available ABSTRACT Optimization of water use in agriculture is fundamental, particularly in regions where water scarcity is intense, requiring the adoption of technologies that promote increased irrigation efficiency. The objective of this study was to evaluate evapotranspiration models and to estimate the crop coefficients of beet grown in a drainage lysimeter in the Agreste region of Alagoas. The experiment was conducted at the Campus of the Federal University of Alagoas - UFAL, in the municipality of Arapiraca, AL, between March and April 2014. Crop evapotranspiration (ETc was estimated in drainage lysimeters and reference evapotranspiration (ETo by Penman-Monteith-FAO 56 and Hargreaves-Samani methods. The Hargreaves-Samani method presented a good performance index for ETo estimation compared with the Penman-Monteith-FAO method, indicating that it is adequate for the study area. Beet ETc showed a cumulative demand of 202.11 mm for a cumulative reference evapotranspiration of 152.00 mm. Kc values determined using the Penman-Monteith-FAO 56 and Hargreaves-Samani methods were overestimated, in comparison to the Kc values of the FAO-56 standard method. With the obtained results, it is possible to correct the equations of the methods for the region, allowing for adequate irrigation management.

  4. Iterative algorithms for the input and state recovery from the approximate inverse of strictly proper multivariable systems

    Science.gov (United States)

    Chen, Liwen; Xu, Qiang

    2018-02-01

    This paper proposes new iterative algorithms for the unknown input and state recovery from the system outputs using an approximate inverse of the strictly proper linear time-invariant (LTI) multivariable system. One of the unique advantages from previous system inverse algorithms is that the output differentiation is not required. The approximate system inverse is stable due to the systematic optimal design of a dummy feedthrough D matrix in the state-space model via the feedback stabilization. The optimal design procedure avoids trial and error to identify such a D matrix which saves tremendous amount of efforts. From the derived and proved convergence criteria, such an optimal D matrix also guarantees the convergence of algorithms. Illustrative examples show significant improvement of the reference input signal tracking by the algorithms and optimal D design over non-iterative counterparts on controllable or stabilizable LTI systems, respectively. Case studies of two Boeing-767 aircraft aerodynamic models further demonstrate the capability of the proposed methods.

  5. Reducing the Surface Performance Requirements of a Primary Mirror by Adding a Deformable Mirror in its Optical Path

    Science.gov (United States)

    2015-12-01

    REQUIREMENTS OF A PRIMARY MIRROR BY ADDING A DEFORMABLE MIRROR IN ITS OPTICAL PATH by Ernesto R. Villalba December 2015 Thesis Advisor: Brij...TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE REDUCING THE SURFACE PERFORMANCE REQUIREMENTS OF A PRIMARY MIRROR BY ADDING A...DEFORMABLE MIRROR IN ITS OPTICAL PATH 5. FUNDING NUMBERS 6. AUTHOR(S) Ernesto R. Villalba 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval

  6. Detectors with Improved Near-to-Mid IR Performance and Reduced Cooling Requirements, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — This program will develop an ultra-high performance infrared detector manufacturing technology with improved performance and cost effectiveness, and reduced cooling...

  7. Study on the requirement for the fuel test loop performance in the HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Chul; Kim, Hark Rho

    2000-06-01

    The requirement of the FTL (Fuel Test Loop) performance were investigated to reaffirm the technical feasibility of the FTL facility which is in consideration to install at the HANARO. LH hole in the reflector region and OR3 in the outer core region are considered as candidate sites for the IPS (In-Pile Section) for the analysis purpose. The achievable linear power at test fuel pin(s) and neutron flux levels at the cladding are analyzed in the IPS, which accommodates CANDU or PWR test fuel. The enrichment of test fuels is assumed as natural uranium for CANDU and 3.5% or 5% for PWR. The test fuel configuration is bundle or 7-pin in LH hole but 1-pin in OR site. For the CANDU test fuel, the target linear power of 60kW/m can not be achieved for all cases. For the PWR test fuel, the target linear power of 40kW/m is obtained at fuels located in the direction of the core for only the case of 5% bundle irradiation. From a sensitivity study, the linear power at test fuel is expected to increase at least 30% of the present results if the core bumup effect, optimization of the ratio of fuel-to-moderator number density, etc., are considered in the detail design. Thus, the linear power for PWR fuel is expected to reach the target value, and that for CANDU fuel will reach the target value if enriched fuel is used. The fast neutron flux at the test fuel cladding is estimated for most cases to be lower than one-third of the target value of 10{sup 1}4 n/cm{sup 2}-sec and expected not to reach the target value.

  8. Requirements with rationale and quantitative rules for EMC on future ships

    NARCIS (Netherlands)

    van Leersum, B.J.A.M.

    2016-01-01

    To ensure the performance on equipment and subsystem level in a naval environment, the conventional approach has been to strictly require national and international military standards on equipment and installations. This approach made Electromagnetic Compatibility (EMC) a cost driver in naval

  9. Principles of students’ independent work organization and requirements to its realization

    Directory of Open Access Journals (Sweden)

    Анна Володимирівна Котова

    2015-10-01

    Full Text Available The notion of independent work as didactic phenomenon is analyzed. Its main principles of organization (students’ performance, individualization of learning, affordability of educational material, strictness of tasks, visualization, systematicity and succession in the formation of independent work skills, consciousness and independence of learning etc are elucidated and requirements to its realization are given

  10. Private and social costs of surface mine reforestation performance criteria.

    Science.gov (United States)

    Sullivan, Jay; Amacher, Gregory S

    2010-02-01

    We study the potentially unnecessary costs imposed by strict performance standards for forest restoration of surface coal mines in the Appalachian region under the Surface Mining Control and Reclamation Act of 1977 (SMCRA) that can vary widely across states. Both the unnecessary private costs to the mine operator and costs to society (social costs) are reported for two performance standards, a ground cover requirement, and a seedling survival target. These standards are examined using numerical analyses under a range of site productivity class and market conditions. We show that a strict (90%) ground cover standard may produce an unnecessary private cost of more than $700/ha and a social cost ranging from $428/ha to $710/ha, as compared with a 70% standard. A strict tree survival standard of 1235 trees/ha, as compared with the more typical 1087 trees/ha standard, may produce an unnecessary private cost of approximately $200/ha, and a social cost in the range of $120 to $208/ha. We conclude that strict performance standards may impose substantial unnecessary private costs and social costs, that strict performance standards may be discouraging the choice of forestry as a post-mining land use, and that opportunities exist for reform of reforestation performance standards. Our study provides a basis for evaluating tradeoffs between regulatory efficiency and optimal reforestation effort.

  11. Amino Acid and Protein Requirements: Cognitive Performance, Stress, and Brain Function

    National Research Council Canada - National Science Library

    Lieberman, Harris

    2000-01-01

    .... A particular focus will be the possibility that central demands for amino acids may modify nutritional requirements when individuals are exposed to extreme environments and other stresses associated...

  12. Research on performance requirements of turbofan engine used on carrier-based UAV

    Science.gov (United States)

    Zhao, Shufan; Li, Benwei; Zhang, Wenlong; Wu, Heng; Feng, Tang

    2017-05-01

    According to the mission requirements of the carrier-based unmanned aerial vehicle (UAV), a mode level flight was established to calculate the thrust requirements from altitude 9 km to 13 km. Then, the estimation method of flight profile was used to calculate the weight of UAV in each stage to get the specific fuel consumption requirements of the UAV in standby stage. The turbofan engine of carrier-based UAV should meet the thrust and specific fuel consumption requirements. Finally, the GSP software was used to verify the simulation of a small high-bypass turbofan engine. The conclusion is useful for the turbofan engine selection of carrier-based UAV.

  13. 40 CFR 80.820 - What gasoline is subject to the toxics performance requirements of this subpart?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false What gasoline is subject to the toxics... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Gasoline Toxics Performance Requirements § 80.820 What gasoline is subject to the toxics performance...

  14. 17 CFR 250.95 - Reports required from affiliate service companies and companies principally engaged in performing...

    Science.gov (United States)

    2010-04-01

    ... affiliate service companies and companies principally engaged in performing services. 250.95 Section 250.95... REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service, Sales and Construction Contracts § 250.95 Reports required from affiliate service companies and companies principally engaged in performing services...

  15. A Criterium for the Strict Positivity of the Density of the Law of a Poisson Process

    Directory of Open Access Journals (Sweden)

    Léandre Rémi

    2011-01-01

    Full Text Available We translate in semigroup theory our result (Léandre, 1990 giving a necessary condition so that the law of a Markov process with jumps could have a strictly positive density. This result express, that we have to jump in a finite number of jumps in a "submersive" way from the starting point to the end point if the density of the jump process is strictly positive in . We use the Malliavin Calculus of Bismut type of (Léandre, (2008;2010 translated in semi-group theory as a tool, and the interpretation in semi-group theory of some classical results of the stochastic analysis for Poisson process as, for instance, the formula giving the law of a compound Poisson process.

  16. The effect of 8 days of strict bed rest on the incretin effect in healthy volunteers

    DEFF Research Database (Denmark)

    Nielsen, Signe Tellerup; Harder-Lauridsen, Nina Majlund; Benatti, Fabiana Braga

    2016-01-01

    in the levels of GLP-1 and Glucagon. Bed rest led to a mean loss of 2.4 kg of fat-free mass, and induced insulin resistance evaluated by the Matsuda index, but did not affect the incretin effect (P = 0.6). In conclusion, 8 days of bed rest induces insulin resistance, but we did not see evidence of an associated......Bed rest and physical inactivity are the consequences of hospital admission for many patients. Physical inactivity induces changes in glucose metabolism, but its effect on the incretin effect, which is reduced in, e.g., Type 2 diabetes, is unknown. To investigate how 8 days of strict bed rest...... affects the incretin effect, 10 healthy nonobese male volunteers underwent 8 days of strict bed rest. Before and after the intervention, all volunteers underwent an oral glucose tolerance test (OGTT) followed by an intravenous glucose infusion (IVGI) on the following day to mimic the blood glucose profile...

  17. Detection of low numbers of microplastics in North Sea fish using strict quality assurance criteria.

    Science.gov (United States)

    Hermsen, Enya; Pompe, Renske; Besseling, Ellen; Koelmans, Albert A

    2017-09-15

    We investigated 400 individual fish of four North Sea species: Atlantic Herring, Sprat, Common Dab, and Whiting on ingestion of >20μm microplastic. Strict quality assurance criteria were followed in order to control contamination during the study. Two plastic particles were found in only 1 (a Sprat) out of 400 individuals (0.25%, with a 95% confidence interval of 0.09-1.1%). The particles were identified to consist of polymethylmethacrylate (PMMA) through FTIR spectroscopy. No contamination occurred during the study, showing the method applied to be suitable for microplastic ingestion studies in biota. We discuss the low particle count for North Sea fish with those in other studies and suggest a relation between reported particle count and degree of quality assurance applied. Microplastic ingestion by fish may be less common than thought initially, with low incidence shown in this study, and other studies adhering to strict quality assurance criteria. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. A strict anaerobic extreme thermophilic hydrogen-producing culture enriched from digested household waste

    DEFF Research Database (Denmark)

    Karakashev, Dimitar Borisov; Kotay, Shireen Meher; Trably, Eric

    2009-01-01

    sources. Growth on glucose produced acetate, H-2 and carbon dioxide. Maximal H-2 production rate on glucose was 1.1 mmol l(-1) h(-1) with a maximum H-2 yield of 1.9 mole H-2 per mole glucose. 16S ribosomal DNA clone library analyses showed that the culture members were phylogenetically affiliated......The aim of this study was to enrich, characterize and identify strict anaerobic extreme thermophilic hydrogen (H-2) producers from digested household solid wastes. A strict anaerobic extreme thermophilic H-2 producing bacterial culture was enriched from a lab-scale digester treating household...... wastes at 70 degrees C. The enriched mixed culture consisted of two rod-shaped bacterial members growing at an optimal temperature of 80 degrees C and an optimal pH 8.1. The culture was able to utilize glucose, galactose, mannose, xylose, arabinose, maltose, sucrose, pyruvate and glycerol as carbon...

  19. Weak asymptotic solution for a non-strictly hyperbolic system of conservation laws-II

    Directory of Open Access Journals (Sweden)

    Manas Ranjan Sahoo

    2016-04-01

    Full Text Available In this article we introduce a concept of entropy weak asymptotic solution for a system of conservation laws and construct the same for a prolonged system of conservation laws which is highly non-strictly hyperbolic. This is first done for Riemann type initial data by introducing $\\delta,\\delta',\\delta''$ waves along a discontinuity curve and then for general initial data by piecing together the Riemann solutions.

  20. Multiple-Set Split Feasibility Problems for κ-Strictly Pseudononspreading Mapping in Hilbert Spaces

    Directory of Open Access Journals (Sweden)

    Jing Quan

    2013-01-01

    Full Text Available The purpose of this paper is to prove some weak and strong convergence theorems for solving the multiple-set split feasibility problems for κ-strictly pseudononspreading mapping in infinite-dimensional Hilbert spaces by using the proposed iterative method. The main results presented in this paper extend and improve the corresponding results of Xu et al. (2006, of Osilike et al. (2011, and of many other authors.

  1. Multiobjective Optimization for the Forecasting Models on the Base of the Strictly Binary Trees

    OpenAIRE

    Nadezhda Astakhova; Liliya Demidova; Evgeny Nikulchev

    2016-01-01

    The optimization problem dealing with the development of the forecasting models on the base of strictly binary trees has been considered. The aim of paper is the comparative analysis of two optimization variants which are applied for the development of the forecasting models. Herewith the first optimization variant assumes the application of one quality indicator of the forecasting model named as the affinity indicator and the second variant realizes the application of two quality indicators ...

  2. Cannabis legalization with strict regulation, the overall superior policy option for public health.

    Science.gov (United States)

    Rehm, J; Fischer, B

    2015-06-01

    Cannabis is the most prevalently used drug globally, with many jurisdictions considering varying reform options to current policies to deal with this substance and associated harm. Three policy options are available: prohibition, decriminalization, and legalization, with prohibition currently the dominant model globally. This contribution gives reasons why legalization with strict regulation should be considered superior to other options with respect to public health in high income countries in North America. © 2015 ASCPT.

  3. Online Recorded Data-Based Composite Neural Control of Strict-Feedback Systems With Application to Hypersonic Flight Dynamics.

    Science.gov (United States)

    Xu, Bin; Yang, Daipeng; Shi, Zhongke; Pan, Yongping; Chen, Badong; Sun, Fuchun

    2017-09-25

    This paper investigates the online recorded data-based composite neural control of uncertain strict-feedback systems using the backstepping framework. In each step of the virtual control design, neural network (NN) is employed for uncertainty approximation. In previous works, most designs are directly toward system stability ignoring the fact how the NN is working as an approximator. In this paper, to enhance the learning ability, a novel prediction error signal is constructed to provide additional correction information for NN weight update using online recorded data. In this way, the neural approximation precision is highly improved, and the convergence speed can be faster. Furthermore, the sliding mode differentiator is employed to approximate the derivative of the virtual control signal, and thus, the complex analysis of the backstepping design can be avoided. The closed-loop stability is rigorously established, and the boundedness of the tracking error can be guaranteed. Through simulation of hypersonic flight dynamics, the proposed approach exhibits better tracking performance.

  4. Global neural dynamic surface tracking control of strict-feedback systems with application to hypersonic flight vehicle.

    Science.gov (United States)

    Xu, Bin; Yang, Chenguang; Pan, Yongping

    2015-10-01

    This paper studies both indirect and direct global neural control of strict-feedback systems in the presence of unknown dynamics, using the dynamic surface control (DSC) technique in a novel manner. A new switching mechanism is designed to combine an adaptive neural controller in the neural approximation domain, together with the robust controller that pulls the transient states back into the neural approximation domain from the outside. In comparison with the conventional control techniques, which could only achieve semiglobally uniformly ultimately bounded stability, the proposed control scheme guarantees all the signals in the closed-loop system are globally uniformly ultimately bounded, such that the conventional constraints on initial conditions of the neural control system can be relaxed. The simulation studies of hypersonic flight vehicle (HFV) are performed to demonstrate the effectiveness of the proposed global neural DSC design.

  5. Monolithic InP strictly non-blocking 8×8 switch for high-speed WDM optical interconnection.

    Science.gov (United States)

    Kwack, Myung-Joon; Tanemura, Takuo; Higo, Akio; Nakano, Yoshiaki

    2012-12-17

    A strictly non-blocking 8 × 8 switch for high-speed WDM optical interconnection is realized on InP by using the phased-array scheme for the first time. The matrix switch architecture consists of over 200 functional devices such as star couplers, phase-shifters and so on without any waveguide cross-section. We demonstrate ultra-broad optical bandwidth covering the entire C-band through several Input/Output ports combination with extinction ratio performance of more than 20dB. Also, nanoseconds reconfiguration time was successfully achieved by dynamic switching experiment. Error-free transmission was verified for 40-Gbps (10-Gbps × 4ch) WDM signal.

  6. Examination of the PCICE method in the nearly incompressible, as well as strictly incompressible, limits

    International Nuclear Information System (INIS)

    Berry, Ray A.; Martineau, Richard C.

    2007-01-01

    The conservative-form, pressure-based PCICE numerical method (Martineau and Berry, 2004) (Berry, 2006), recently developed for computing transient fluid flows of all speeds from very low to very high (with strong shocks), is simplified and generalized. Though the method automatically treats a continuous transition of compressibility, three distinct, limiting compressibility regimes are formally defined for purposes of discussion and comparison with traditional methods - the strictly incompressible limit, the nearly incompressible limit, and the fully compressible limit. The PCICE method's behavior is examined in each limiting regime. In the strictly incompressible limit the PCICE algorithm reduces to the traditional MAC-type method with velocity divergence driving the pressure Poisson equation. In the nearly incompressible limit the PCICE algorithm is found to reduce to a generalization of traditional incompressible methods, i.e. to one in which not only the velocity divergence effect, but also the density gradient effect is included as a driving function in the pressure Poisson equation. This nearly incompressible regime has received little attention, and it appears that in the past, strictly incompressible methods may have been conveniently applied to flows in this regime at the expense of ignoring a potentially important coupling mechanism. This could be significant in many important flows; for example, in natural convection flows resulting from high heat flux. In the fully compressible limit or regime, the algorithm is found to reduce to an expression equivalent to density-based methods for high-speed flow. (author)

  7. TESTING STRICT HYDROSTATIC EQUILIBRIUM IN SIMULATED CLUSTERS OF GALAXIES: IMPLICATIONS FOR A1689

    International Nuclear Information System (INIS)

    Molnar, S. M.; Umetsu, K.; Chiu, I.-N.; Chen, P.; Hearn, N.; Broadhurst, T.; Bryan, G.; Shang, C.

    2010-01-01

    Accurate mass determination of clusters of galaxies is crucial if they are to be used as cosmological probes. However, there are some discrepancies between cluster masses determined based on gravitational lensing and X-ray observations assuming strict hydrostatic equilibrium (i.e., the equilibrium gas pressure is provided entirely by thermal pressure). Cosmological simulations suggest that turbulent gas motions remaining from hierarchical structure formation may provide a significant contribution to the equilibrium pressure in clusters. We analyze a sample of massive clusters of galaxies drawn from high-resolution cosmological simulations and find a significant contribution (20%-45%) from non-thermal pressure near the center of relaxed clusters, and, in accord with previous studies, a minimum contribution at about 0.1 R vir , growing to about 30%-45% at the virial radius, R vir . Our results strongly suggest that relaxed clusters should have significant non-thermal support in their core region. As an example, we test the validity of strict hydrostatic equilibrium in the well-studied massive galaxy cluster A1689 using the latest high-resolution gravitational lensing and X-ray observations. We find a contribution of about 40% from non-thermal pressure within the core region of A1689, suggesting an alternate explanation for the mass discrepancy: the strict hydrostatic equilibrium is not valid in this region.

  8. Temporary Strict Maternal Avoidance of Cow’s Milk and Infantile Colic

    Directory of Open Access Journals (Sweden)

    Firoozeh Sajedi

    2009-12-01

    Full Text Available Infant colic is a common problem characterized by excessive crying and fussing. We examined whether colic symptoms of exclusively breast-milk-fed infants would be improved by temporary strict maternal avoidance of cows milk. This study is analytic and experimental. Sixty-six subjects were recruited during winter of 2006 from a clinic in Isfahan, Iran. Breast-milk-fed in-fants with "colic", age 3-6 months and to be in otherwise good health were referred by pediatri-cians. The intervention was 1 week period of strict maternal avoidance of cows milk while they continued exclusive breast-milk-feeding. All infants showed improvement in distressed behavior (crying and fussing during intervention. The total recorded crying and fussing time was reduced by an average of 31%. A significant difference was found in cry and fuss time between first and last 2 days of intervention (P = 0.000. Cows milk proteins may play an etiologic role in colic. We propose that a brief intervention with strict maternal avoidance of cows milk may be an effective treatment for colic in some breast-milk-fed infants.

  9. An Empirical Assessment of the Impact of Requirements Uncertainty on Development Quality Performance

    National Research Council Canada - National Science Library

    Aldaijy, Ayad Y

    2004-01-01

    .... The main purpose of this research is to examine the impact of requirements uncertainty and task uncertainty on outcomes in software development projects, limiting the attention to process and product quality...

  10. 40 CFR 63.1207 - What are the performance testing requirements?

    Science.gov (United States)

    2010-07-01

    ... availability of the test plans and the location where the test plans are available for review. The test plans... on the carbon used during the performance test, if you elect not to specify and use the brand and... brand and type of carbon used during the comprehensive performance test, you must include in the...

  11. 46 CFR 160.057-3 - Materials, workmanship, construction, and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, workmanship, construction, and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Floating Orange Smoke Distress Signals (15 Minutes) § 160.057-3 Materials, workmanship, construction, and performance...

  12. 46 CFR 160.062-3 - Materials, construction, workmanship, and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, construction, workmanship, and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Releases. Lifesaving Equipment, Hydraulic and Manual § 160.062-3 Materials, construction, workmanship, and performance...

  13. 46 CFR 160.023-3 - Materials, workmanship, construction, and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, workmanship, construction, and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand Combination Flare and Smoke Distress Signals § 160.023-3 Materials, workmanship, construction, and performance...

  14. 46 CFR 160.028-3 - Materials, workmanship, construction, and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, workmanship, construction, and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Signal Pistols for Red Flare Distress Signals § 160.028-3 Materials, workmanship, construction, and performance...

  15. 46 CFR 160.022-3 - Materials, workmanship, construction, and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, workmanship, construction, and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Floating Orange Smoke Distress Signals (5 Minutes) § 160.022-3 Materials, workmanship, construction, and performance...

  16. 46 CFR 160.024-3 - Materials, workmanship, construction, and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, workmanship, construction, and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Pistol-Projected Parachute Red Flare Distress Signals § 160.024-3 Materials, workmanship, construction, and performance...

  17. 46 CFR 160.058-3 - Materials, workmanship, construction and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, workmanship, construction and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Desalter Kits, Sea Water, for Merchant Vessels § 160.058-3 Materials, workmanship, construction and performance...

  18. Rate Control Efficacy in Permanent Atrial Fibrillation : Successful and Failed Strict Rate Control Against a Background of Lenient Rate Control

    NARCIS (Netherlands)

    Groenveld, Hessel F.; Tijssen, Jan G. P.; Crijns, Harry J. G. M.; Van den Berg, Maarten P.; Hillege, Hans L.; Alings, Marco; Van Veldhuisen, Dirk J.; Van Gelder, Isabelle C.

    2013-01-01

    Objectives This study sought to investigate differences in outcome between patients treated with successful strict, failed strict, and lenient rate control. Background The RACE II (Rate Control Efficacy in Permanent Atrial Fibrillation) study showed no difference in outcome between lenient and

  19. Strict versus liberal insulin therapy in the cardiac surgery patient: An evidence-based practice development, implementation and evaluation project.

    Science.gov (United States)

    Gordon, Jacqueline M; Lauver, Lori S; Buck, Harleah G

    2018-02-01

    Hyperglycemia post-cardiac surgery is associated with poor clinical outcomes. Recent studies suggest maintaining liberal glycemic control (liberal CII protocol. Retrospective review of 144 strict CII patient records and 147 liberal CII patient records. Mean blood glucose was 159.8mg/dL (liberal CII) compared to 143.3mg/dL (strict CII) (p≤0.001). No surgical site infections occurred in either group. Mean ICU length of stay was 4.5days (liberal) versus 4.4days (strict) (p=0.74). Two 30-day mortalities occurred for the liberal cohort compared to no deaths in the strict group (p=0.49). Hypoglycemia incidence within 24h after surgery was 0.1% (liberal) compared to 0.3% (strict) compared to (p=0.16). Use of a nurse managed liberal CII resulted in similar outcomes with fewer incidents of hypoglycemia. Copyright © 2017. Published by Elsevier Inc.

  20. 40 CFR Table 4 to Subpart Zzzz of... - Requirements for Performance Tests

    Science.gov (United States)

    2010-07-01

    ... Internal Combustion Engines Pt. 63, Subpt. ZZZZ, Table 4 Table 4 to Subpart ZZZZ of Part 63—Requirements... followingrequirements . . . 1. 2SLB, 4SLB, and CI stationary RICE a. Reduce CO emissions i. Measure the O2 at the inlet... both CI and SI stationary RICE. b You may also use Method 320 of 40 CFR part 63, appendix A, or ASTM...

  1. Job Language Performance Requirements for MOS 16P. Short Range Air Defense Artillery Missile Crewman.

    Science.gov (United States)

    1982-10-01

    CONDITIONS: Givtn any requirement to produce b mitten re#rt STANDARDS: 100% legible written content I TASK NUMBER AND TITLE 441-16P-1001 Apply the four- lift...fcreign forward"- ( .1 rully gentile has head heart heartbeat high hold immediately important infants inserting interlace kept less (es likely lips

  2. 75 FR 76254 - Official Performance and Procedural Requirements for Grain Weighing Equipment and Related Grain...

    Science.gov (United States)

    2010-12-08

    ...: Section 1.10 General Code Section 2.20 Scales Section 2.22 Automatic Bulk Weighing Systems Section 2.23... Weighing Handbook, the General Code, the Scales Code, the Automatic Bulk Weighing Systems Code, and the... requirements are not incorporated by reference: Scales (2.20) S.1.8. Computing Scales S.1.8.2. Money-Value...

  3. 40 CFR 60.255 - Performance tests and other compliance requirements.

    Science.gov (United States)

    2010-07-01

    ... presence of visible emissions must meet the training requirements specified in § 2.3 of Method 22 of.... EPA); Office of Air Quality and Planning Standards; Sector Policies and Programs Division; Measurement... certified neutral density filter or other related technique to produce a known obscuration of the light beam...

  4. Minimizing the energy requirement of dewatering scenedesmus sp. by microfiltration: performance, costs, and feasibility.

    Science.gov (United States)

    Gerardo, Michael L; Oatley-Radcliffe, Darren L; Lovitt, Robert W

    2014-01-01

    The harvesting of the microalgae Scenedesmus species using a 200 L pilot-scale microfiltration system was investigated and critically assessed. The energy requirement was determined and correlated to the different operating parameters, such as transmembrane pressure (ΔP), membrane area, temperature, and initial biomass concentration. A filtration model was developed and showed a strong correlation with experimental data up to 20.0 g of dry cell weight (DCW)/L. The non-optimized filtration system had an energy requirement of 2.23 kWh/m(3) with an associated cost of $0.282/kg of microalgae. The investigation into the influence of the operating parameters and scale-up effects showed that the energy requirement could be substantially reduced to 0.90 kWh/m(3) and $0.058/kg of microalgae harvested. Maintenance costs associated with cleaning were estimated to be 0.23 kWh or $0.029/batch of microalgae processed. Dependent upon the operating conditions, harvesting may represent 6-45% of the energy embedded in the microalgae with a carbon footprint of 0.74-1.67 kg of CO2/kg of microalgae. Microfiltration was demonstrated to be a feasible microalgae harvesting technology allowing for more than 99% volume reduction. The energy requirement and associated carbon footprint of microalgae harvesting reported here do not forfeit the need for an industrial-scale study; however, the information provided presents a more realistic approximation than the literature reported to date.

  5. 14 CFR 135.183 - Performance requirements: Land aircraft operated over water.

    Science.gov (United States)

    2010-01-01

    ... operated over water. 135.183 Section 135.183 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... AND OPERATIONS OPERATING REQUIREMENTS: COMMUTER AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS... operated over water. No person may operate a land aircraft carrying passengers over water unless— (a) It is...

  6. 40 CFR Table 4 to Subpart Dddd of... - Requirements for Performance Tests

    Science.gov (United States)

    2010-07-01

    ... constructing a TTE according to the requirements of Method 204 and applying Methods 204A through 204F (as... option in table 1A to this subpart determine the percent capture efficiency a TTE and Methods 204 and 204A through 204F (as appropriate) of 40 CFR part 51, appendix M. As an alternative to installing a TTE...

  7. Detectors with Improved Near-to-Mid IR Performance and Reduced Cooling Requirements, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This STTR Phase I proposal addresses a NASA need for improved near-to-mid IR detectors for imaging and spectroscopy. High performance IR detectors with cutoff...

  8. Inspection Report: FAA's Alleged Circumvention of National Performance Review Staffing Requirements

    Science.gov (United States)

    1996-12-09

    This report responds to a complaint received by the Office of Inspector General : (OIG), Department of Transportation. The complainant alleges the Federal : Aviation Administration (FAA) planned to circumvent National Performance : Review (NPR) staff...

  9. Agronomic traits and deoxynivalenol contamination of two tetraploid wheat species (Triticum turgidum spp. durum, Triticum turgidum spp. turanicum grown strictly under low input conditions

    Directory of Open Access Journals (Sweden)

    Giovanni Dinelli

    2014-09-01

    Full Text Available An evaluation of the agronomic performance of two tetraploid wheat varieties (Triticum turgidum spp. durum, Claudio; Triticum turgidum spp. turanicum, Kamut® grown strictly under low input conditions was carried out over three consecutive cropping years. The study reported grain yield values ranging from 1.8 to 2.6 t ha-1. Productivity showed to be primarily affected by environmental conditions, while no differences were observed between the two genotypes. The study of the yield components highlighted that the durum wheat variety had a higher plant density than Kamut®, but this discrepancy was offset by a greater number of kernels per spike and the kernel weight of khorasan wheat. The investigated wheat genotypes were also analysed to assess the mycotoxin (DON levels of wholegrain semolina and the efficiency of cleaning treatments to reduce contamination. Results showed that both wheat varieties had a good hygienic and sanitary quality with a DON content ranging from 0.35 to 1.31 mg kg-1, which was lower than the maximum acceptable level set by the European regulation at 1.75 mg kg-1. In addition, our research work investigated the effects of premilling cleaning procedures, such as water washing and brushing, on mycotoxin levels, which yielded interesting results in terms of decontamination efficiency. These methods were particularly efficient with Kamut® semolina (46-93% DON reduction, suggesting that mycotoxins accumulate in this variety at more superficial levels than in the durum wheat variety. On the whole, our study provided additional knowledge on the traits to be further improved to respond to low input requirements and to enhance the potential adaptability of wheat genotypes to organic agriculture. Our results emphasized the need to develop wheat varieties that can provide adequate performance without high levels of nitrogen inputs by selecting specific traits, such as kernel weight, spike length and kernel/spike. This may help

  10. Virtual environment to quantify the influence of colour stimuli on the performance of tasks requiring attention

    OpenAIRE

    Frère Annie F; Silva Alessandro P

    2011-01-01

    Abstract Background Recent studies indicate that the blue-yellow colour discrimination is impaired in ADHD individuals. However, the relationship between colour and performance has not been investigated. This paper describes the development and the testing of a virtual environment that is capable to quantify the influence of red-green versus blue-yellow colour stimuli on the performance of people in a fun and interactive way, being appropriate for the target audience. Methods An interactive c...

  11. RelTime Rates Collapse to a Strict Clock When Estimating the Timeline of Animal Diversification.

    Science.gov (United States)

    Lozano-Fernandez, Jesus; Dos Reis, Mario; Donoghue, Philip C J; Pisani, Davide

    2017-05-01

    Establishing an accurate timescale for the history of life is crucial to understand evolutionary processes. For this purpose, relaxed molecular clock models implemented in a Bayesian MCMC framework are generally used. However, these methods are time consuming. RelTime, a non-Bayesian method implementing a fast, ad hoc, algorithm for relative dating, was developed to overcome the computational inefficiencies of Bayesian software. RelTime was recently used to investigate the timing of origin of animals, yielding results consistent with early strict clock studies from the 1980s and 1990s, estimating metazoans to have a Mesoproterozoic origin-over a billion years ago. RelTime results are unexpected and disagree with the largest majority of modern, relaxed, Bayesian molecular clock analyses, which suggest animals originated in the Tonian-Cryogenian (less that 850 million years ago). Here, we demonstrate that RelTime-inferred divergence times for the origin of animals are spurious, a consequence of the inability of RelTime to relax the clock along the internal branches of the animal phylogeny. RelTime-inferred divergence times are comparable to strict-clock estimates because they are essentially inferred under a strict clock. Our results warn us of the danger of using ad hoc algorithms making implicit assumptions about rate changes along a tree. Our study roundly rejects a Mesoproterozoic origin of animals; metazoans emerged in the Tonian-Cryogenian, and diversified in the Ediacaran, in the immediate prelude to the routine fossilization of animals in the Cambrian associated with the emergence of readily preserved skeletons. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  12. Effect of cryopreservation and lyophilization on viability and growth of strict anaerobic human gut microbes.

    Science.gov (United States)

    Bircher, Lea; Geirnaert, Annelies; Hammes, Frederik; Lacroix, Christophe; Schwab, Clarissa

    2018-04-17

    Strict anaerobic gut microbes have been suggested as 'next-generation probiotics' for treating several intestinal disorders. The development of preservation techniques is of major importance for therapeutic application. This study investigated cryopreservation (-80°C) and lyophilization survival and storage stability (4°C for 3 months) of the strict anaerobic gut microbes Bacteroides thetaiotaomicron, Faecalibacterium prausnitzii, Roseburia intestinalis, Anaerostipes caccae, Eubacterium hallii and Blautia obeum. To improve preservation survival, protectants sucrose and inulin (both 5% w/v) were added for lyophilization and were also combined with glycerol (15% v/v) for cryopreservation. Bacterial fitness, evaluated by maximum growth rate and lag phase, viability and membrane integrity were determined using a standardized growth assay and by flow cytometry as markers for preservation resistance. Lyophilization was more detrimental to viability and fitness than cryopreservation, but led to better storage stability. Adding sucrose and inulin enhanced viability and the proportion of intact cells during lyophilization of all strains. Viability of protectant-free B. thetaiotaomicron, A. caccae and F. prausnitzii was above 50% after cryopreservation and storage and increased to above 80% if protectants were present. The addition of glycerol, sucrose and inulin strongly enhanced the viability of B. obeum, E. hallii and R. intestinalis from 0.03-2% in protectant-free cultures to 11-37%. This is the first study that quantitatively compared the effect of cryopreservation and lyophilization and the addition of selected protectants on viability and fitness of six strict anaerobic gut microbes. Our results suggest that efficiency of protectants is process- and species-specific. © 2018 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology.

  13. Uncertainty Requirement Analysis for the Orbit, Attitude, and Burn Performance of the 1st Lunar Orbit Insertion Maneuver

    Directory of Open Access Journals (Sweden)

    Young-Joo Song

    2016-12-01

    Full Text Available In this study, the uncertainty requirements for orbit, attitude, and burn performance were estimated and analyzed for the execution of the 1st lunar orbit insertion (LOI maneuver of the Korea Pathfinder Lunar Orbiter (KPLO mission. During the early design phase of the system, associate analysis is an essential design factor as the 1st LOI maneuver is the largest burn that utilizes the onboard propulsion system; the success of the lunar capture is directly affected by the performance achieved. For the analysis, the spacecraft is assumed to have already approached the periselene with a hyperbolic arrival trajectory around the moon. In addition, diverse arrival conditions and mission constraints were considered, such as varying periselene approach velocity, altitude, and orbital period of the capture orbit after execution of the 1st LOI maneuver. The current analysis assumed an impulsive LOI maneuver, and two-body equations of motion were adapted to simplify the problem for a preliminary analysis. Monte Carlo simulations were performed for the statistical analysis to analyze diverse uncertainties that might arise at the moment when the maneuver is executed. As a result, three major requirements were analyzed and estimated for the early design phase. First, the minimum requirements were estimated for the burn performance to be captured around the moon. Second, the requirements for orbit, attitude, and maneuver burn performances were simultaneously estimated and analyzed to maintain the 1st elliptical orbit achieved around the moon within the specified orbital period. Finally, the dispersion requirements on the B-plane aiming at target points to meet the target insertion goal were analyzed and can be utilized as reference target guidelines for a mid-course correction (MCC maneuver during the transfer. More detailed system requirements for the KPLO mission, particularly for the spacecraft bus itself and for the flight dynamics subsystem at the ground

  14. Effects of growth temperature and strictly anaerobic recovery on the survival of Listeria monocytogenes during pasteurization.

    OpenAIRE

    Knabel, S J; Walker, H W; Hartman, P A; Mendonca, A F

    1990-01-01

    Listeria monocytogenes F5069 was suspended in either Trypticase soy broth-0.6% yeast extract (TSBYE) or sterile, whole milk and heated at 62.8 degrees C in sealed thermal death time tubes. Severely heat-injured cells were recovered in TSBYE within sealed thermal death time tubes because of the formation of reduced conditions in the depths of the TSBYE. Also, the use of strictly anaerobic Hungate techniques significantly increased recovery in TSBYE containing 1.5% agar compared with aerobicall...

  15. The Dirichlet problem for the Monge-Ampere equation in convex (but not strictly convex domains

    Directory of Open Access Journals (Sweden)

    David Hartenstine

    2006-10-01

    Full Text Available It is well-known that the Dirichlet problem for the Monge-Amp`ere equation $det D^2 u = mu$ in a bounded strictly convex domain $Omega$ in $mathbb{R}^n$ has a weak solution (in the sense of Aleksandrov for any finite Borel measure $mu$ on $Omega$ and for any continuous boundary data. We consider the Dirichlet problem when $Omega$ is only assumed to be convex, and give a necessary and sufficient condition on the boundary data for solvability.

  16. Selections of the metric projection operator and strict solarity of sets with continuous metric projection

    Science.gov (United States)

    Alimov, A. R.

    2017-07-01

    In a broad class of finite-dimensional Banach spaces, we show that a closed set with lower semicontinuous metric projection is a strict sun, admits a continuous selection of the metric projection operator onto it, has contractible intersections with balls, and its (nonempty) intersection with any closed ball is a retract of this ball. For sets with continuous metric projection, a number of new results relating the solarity of such sets to the stability of the operator of best approximation are obtained. Bibliography 25 titles.

  17. Transplanting Diseases from Organ Donors in Western Europe: Fault Liability or Strict Liability?

    Science.gov (United States)

    Broeckx, Nils; Verhoeven, Dimitri

    2015-06-01

    This article will examine the problem of disease transmission through organ transplantation from a civil liability perspective. Both fault liability and strict product liability might be possible. These two types of liability will be compared, while applying them to the actions of the central parties involved in organ donation and transplantation, namely the physician/hospital, the donor and the organ exchange organisation. While product liability is generally an easier way to obtain compensation than fault liability, it might nevertheless place too heavy a burden on the transplant professionals.

  18. Molecular mechanism of strict substrate specificity of an extradiol dioxygenase, DesB, derived from Sphingobium sp. SYK-6.

    Directory of Open Access Journals (Sweden)

    Keisuke Sugimoto

    Full Text Available DesB, which is derived from Sphingobium sp. SYK-6, is a type II extradiol dioxygenase that catalyzes a ring opening reaction of gallate. While typical extradiol dioxygenases show broad substrate specificity, DesB has strict substrate specificity for gallate. The substrate specificity of DesB seems to be required for the efficient growth of S. sp. SYK-6 using lignin-derived aromatic compounds. Since direct coordination of hydroxyl groups of the substrate to the non-heme iron in the active site is a critical step for the catalytic reaction of the extradiol dioxygenases, the mechanism of the substrate recognition and coordination of DesB was analyzed by biochemical and crystallographic methods. Our study demonstrated that the direct coordination between the non-heme iron and hydroxyl groups of the substrate requires a large shift of the Fe (II ion in the active site. Mutational analysis revealed that His124 and His192 in the active site are essential to the catalytic reaction of DesB. His124, which interacts with OH (4 of the bound gallate, seems to contribute to proper positioning of the substrate in the active site. His192, which is located close to OH (3 of the gallate, is likely to serve as the catalytic base. Glu377' interacts with OH (5 of the gallate and seems to play a critical role in the substrate specificity. Our biochemical and structural study showed the substrate recognition and catalytic mechanisms of DesB.

  19. 20 CFR 663.540 - What kind of performance and cost information is required for determinations of subsequent...

    Science.gov (United States)

    2010-04-01

    ...; or (2) The Governor must provide additional resources to assist providers in the collection of the... TITLE I OF THE WORKFORCE INVESTMENT ACT Eligible Training Providers § 663.540 What kind of performance and cost information is required for determinations of subsequent eligibility? (a) Eligible providers...

  20. 42 CFR 84.159 - Man tests for gases and vapors; supplied-air respirators; general performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Man tests for gases and vapors; supplied-air respirators; general performance requirements. 84.159 Section 84.159 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES...

  1. 42 CFR 433.123 - Notification of changes in system requirements, performance standards or other conditions for...

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Notification of changes in system requirements, performance standards or other conditions for approval or reapproval. 433.123 Section 433.123 Public Health... ASSISTANCE PROGRAMS STATE FISCAL ADMINISTRATION Mechanized Claims Processing and Information Retrieval...

  2. 48 CFR 225.7401 - Contracts requiring performance or delivery in a foreign country.

    Science.gov (United States)

    2010-10-01

    ... personnel other than host country personnel, or delivery of items to a Unified Combatant Command designated...://www.per.hqusareur.army.mil/cpd/docper/GermanyDefault.aspx. (c) For work performed in Japan or Korea, see PGI 225.7401(c) for information on bilateral agreements and policy relating to contractor...

  3. Determining required valve performance for discrete control of PTO cylinders for wave energy

    DEFF Research Database (Denmark)

    Hansen, Rico Hjerm; Andersen, Torben Ole; Pedersen, Henrik C.

    2012-01-01

    on a floating body, throttle-less force control by discrete variation of the effective cylinder area has been investigated and found feasible for the Wavestar wave energy concept. However, the feasibility study assumes adequate valve performance, such that only the compression loss remains. This paper...

  4. 40 CFR 63.344 - Performance test requirements and test methods.

    Science.gov (United States)

    2010-07-01

    ... be made available to the Administrator prior to the testing, if requested. (1) A brief process... this part, was used to demonstrate the performance of a control technique are not acceptable. (c) Test... chromium emissions. For the purposes of this standard, sources using chromic acid baths can demonstrate...

  5. 40 CFR Table 4 to Subpart Kkkkk of... - Requirements for Performance Tests

    Science.gov (United States)

    2010-07-01

    ..., appendix A. c. Conduct gas molecular weight analysis Method 3 of 40 CFR part 60, appendix A You may use... CFR part 60, appendix A. d. Measure moisture content of the stack gas Method 4 of 40 CFR part 60... the average scrubber liquid pH Data from the pH measurement device during the performance test You...

  6. 46 CFR 160.031-3 - Materials, construction, workmanship, and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, construction, workmanship, and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Line-Throwing Appliance, Shoulder Gun Type (and Equipment) § 160.031-3 Materials, construction, workmanship, and...

  7. 46 CFR 160.036-3 - Materials, workmanship, construction and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, workmanship, construction and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand-Held Rocket-Propelled Parachute Red Flare Distress Signals § 160.036-3 Materials, workmanship, construction and...

  8. 46 CFR 160.040-3 - Materials, construction, workmanship, and performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, construction, workmanship, and performance...) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Line-Throwing Appliance, Impulse-Projected Rocket Type (and Equipment) § 160.040-3 Materials, construction, workmanship...

  9. Fuzzy Adaptive Decentralized Optimal Control for Strict Feedback Nonlinear Large-Scale Systems.

    Science.gov (United States)

    Sun, Kangkang; Sui, Shuai; Tong, Shaocheng

    2018-04-01

    This paper considers the optimal decentralized fuzzy adaptive control design problem for a class of interconnected large-scale nonlinear systems in strict feedback form and with unknown nonlinear functions. The fuzzy logic systems are introduced to learn the unknown dynamics and cost functions, respectively, and a state estimator is developed. By applying the state estimator and the backstepping recursive design algorithm, a decentralized feedforward controller is established. By using the backstepping decentralized feedforward control scheme, the considered interconnected large-scale nonlinear system in strict feedback form is changed into an equivalent affine large-scale nonlinear system. Subsequently, an optimal decentralized fuzzy adaptive control scheme is constructed. The whole optimal decentralized fuzzy adaptive controller is composed of a decentralized feedforward control and an optimal decentralized control. It is proved that the developed optimal decentralized controller can ensure that all the variables of the control system are uniformly ultimately bounded, and the cost functions are the smallest. Two simulation examples are provided to illustrate the validity of the developed optimal decentralized fuzzy adaptive control scheme.

  10. AREVA's fuel assemblies addressing high performance requirements of the worldwide PWR fleet

    International Nuclear Information System (INIS)

    Anniel, Marc; Bordy, Michel-Aristide

    2009-01-01

    Taking advantage of its presence in the fuel activities since the start of commercial nuclear worldwide operation, AREVA is continuing to support the customers with the priority on reliability, to: >participate in plant operational performance for the in core fuel reliability, the Zero Tolerance for Failure ZTF as a continuous improvement target and the minimisation of manufacturing/quality troubles, >guarantee the supply chain a proven product stability and continuous availability, >support performance improvements with proven design and technology for fuel management updating and cycle cost optimization, >support licensing assessments for fuel assembly and reloads, data/methodologies/services, >meet regulatory challenges regarding new phenomena, addressing emergent performance issues and emerging industry challenges for changing operating regimes. This capacity is based on supplies by AREVA accumulating very large experience both in manufacturing and in plant operation, which is demonstrated by: >manufacturing location in 4 countries including 9 fuel factories in USA, Germany, Belgium and France. Up to now about 120,000 fuel assemblies and 8,000 RCCA have been released to PWR nuclear countries, from AREVA European factories, >irradiation performed or in progress in about half of PWR world wide nuclear plants. Our optimum performances cover rod burn ups of to 82GWD/tU and fuel assemblies successfully operated under various world wide fuel management types. AREVA's experience, which is the largest in the world, has the extensive support of the well known fuel components such as the M5'TM'cladding, the MONOBLOC'TM'guide tube, the HTP'TM' and HMP'TM' structure components and the comprehensive services brought in engineering, irradiation and post irradiation fields. All of AREVA's fuel knowledge is devoted to extend the definition of fuel reliability to cover the whole scope of fuel vendor support. Our Top Reliability and Quality provide customers with continuous

  11. Which are structural requirements for the effective performance of waste management institutions?

    International Nuclear Information System (INIS)

    Espejo, P.

    2000-01-01

    In this talk I offer a structural interpretation of the issue of transparency. Transparency requires fostering, producing and maintaining distributed dialogues and communications between those affected by ('the stakeholders') and those producing relevant expert knowledge ('the experts') and those producing related decisions ('the decision makers'). The issues raised in these dialogues will not only refer to questions of technical efficiency, but also to questions of what is right and fair and whether the decisions and their implementation reflect what society considers to be good. (author)

  12. High Performance Computing and Storage Requirements for Biological and Environmental Research Target 2017

    Energy Technology Data Exchange (ETDEWEB)

    Gerber, Richard [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). National Energy Research Scientific Computing Center (NERSC); Wasserman, Harvey [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). National Energy Research Scientific Computing Center (NERSC)

    2013-05-01

    The National Energy Research Scientific Computing Center (NERSC) is the primary computing center for the DOE Office of Science, serving approximately 4,500 users working on some 650 projects that involve nearly 600 codes in a wide variety of scientific disciplines. In addition to large-­scale computing and storage resources NERSC provides support and expertise that help scientists make efficient use of its systems. The latest review revealed several key requirements, in addition to achieving its goal of characterizing BER computing and storage needs.

  13. Use of performance curves in estimating number of procedures required to achieve proficiency in coronary angiography

    DEFF Research Database (Denmark)

    Räder, Sune B E W; Jørgensen, Erik; Bech, Bo

    2011-01-01

    .001 for all parameters. To approach the experts' level of DAP and contrast media use, trainees need 394 and 588 procedures, respectively. Performance curves showed large individual differences in the development of competence. Conclusion: On average, trainees needed 300 procedures to reach sufficient level...... needed for trainees to reach recommended reference levels was estimated as 226 and 353, for DAP and use of contrast media, respectively. After 300 procedures, trainees' procedure time, fluoroscopy time, DAP, and contrast media volume were significantly higher compared with experts' performance, P ...Background: Current guidelines in cardiology training programs recommend 100-300 coronary angiography procedures for certification. We aimed to assess the number of procedures needed to reach sufficient proficiency. Methods: Procedure time, fluoroscopy time, dose area product (DAP), and contrast...

  14. Army Officer Job Analysis: Identifying Performance Requirements to Inform Officer Selection and Assignment

    Science.gov (United States)

    2011-08-01

    officers spend time in these two positions, and they provide the earliest points at which officer job performance can be evaluated. Army-Wide...seems potentially relevant for the leadership MD labeled “Maintain mental health and well-being.”7 Job Embeddedness . Job embeddedness refers to...organization (referred to as sacrifice). Mitchell, Holtom, Lee, Sablynski, and Erez (2001) offered job embeddedness to help explain the fact that

  15. Validation of vertical refractivity profiles as required for performance prediction of coastal surveillance radars

    CSIR Research Space (South Africa)

    Naicker, K

    2011-04-01

    Full Text Available for modeling the detection performance of coastal surveillance radars. Validation is provided through meteorological and radio wave propagation measurements undertaken in False Bay, South Africa. Keywords-vertical refractive profiles, evaporation ducts.... An atmospheric duct is a horizontal layer in troposphere, where the refractive conditions are such that an EM wave will be channeled or guided as discussed above. This results in EM wave propagation over great ranges. In a littoral environment, evaporation...

  16. Capital Requirements and Banks' Leniency

    DEFF Research Database (Denmark)

    Dietrich, J. Kimball; Wihlborg, Clas

    2003-01-01

    We investigate the effect of changes in capital regulation on the strictness(leniency) of loan terms using a simple model of bank capital requirements andasset quality examinations. Banks offer different levels of `leniency' in the senseof willingness to offer automatic extensions of loans...... rates. As capital requirements increase thedifference between initial capital levels and between interest rates of strict andlenient banks decrease. Thus, higher capital requirements in recessions tend toreduce the interest rate premium paid for leniency. If a recession is interpreted asan increase...... in the required return, the interest rate premium paid for leniency isincreased in recession at a given level of required capital....

  17. Method of Estimating the Principal Characteristics of an Infantry Fighting Vehicle from Basic Performance Requirements

    Science.gov (United States)

    2013-08-01

    If we look only at combat vehicle applications over the last 40 years, we see a continuous evolution of engine design that has resulted in...so there is also a performance impact. Table C-2. Caterpillar 6-Cylinder Diesel Engines Model Power (kW) Weight (kg) Ratio (kW/kg) C6.6 205... Caterpillar , accessed 10 May 2013, http://www.cat.com/cda/files/ 2208849/7/LEGH0002.pdf. Since mean piston speed is a function of materials

  18. Defense Organization Officials Did Not Consistently Comply With Requirements for Assessing Contractor Performance

    Science.gov (United States)

    2017-02-01

    3 FAR Part 42, “Contract Administration and Audit Services ,” Subpart 42.15, “Contractor Performance Information,” 42.1502, “Policy,” 42.1502(a...contracting office, program management office, and where appropriate, quality assurance and end users of the product or service .”11 Contracts may have one or...2009. Introduction 4 │ DODIG-2017-052 Senate Armed Services Committee Request for Audit In a June 4, 2010, Senate Armed Services Committee report, the

  19. The data requirements for the verification and validation of a fuel performance code - the transuranus perspective

    International Nuclear Information System (INIS)

    Schubert, A.; Di Marcello, V.; Rondinella, V.; Van De Laar, J.; Van Uffelen, P.

    2013-01-01

    In general, the verification and validation (V and V) of a fuel performance code like TRANSURANUS consists of three basic steps: a) verifying the correctness and numerical stability of the sub-models; b) comparing the sub-models with experimental data; c) comparing the results of the integral fuel performance code with experimental data Only the second and third steps of the V and V rely on experimental information. This scheme can be further detailed according to the physical origin of the data: on one hand, in-reactor ('in-pile') experimental data are generated in the course of the irradiation; on the other hand ex-reactor ('out-of-pile') experimental data are obtained for instance from various postirradiation examinations (PIE) or dedicated experiments with fresh samples. For both categories, we will first discuss the V and V of sub-models of TRANSURANUS related to separate aspects of the fuel behaviour: this includes the radial variation of the composition and fissile isotopes, the thermal properties of the fuel (e.g. thermal conductivity, melting temperature, etc.), the mechanical properties of fuel and cladding (e.g. elastic constants, creep properties), as well as the models for the fission product behaviour. Secondly, the integral code verification will be addressed as it treats various aspects of the fuel behaviour, including the geometrical changes in the fuel and the gas pressure and composition of the free volume in the rod. (authors)

  20. Disordered strictly jammed binary sphere packings attain an anomalously large range of densities

    Science.gov (United States)

    Hopkins, Adam B.; Stillinger, Frank H.; Torquato, Salvatore

    2013-08-01

    Previous attempts to simulate disordered binary sphere packings have been limited in producing mechanically stable, isostatic packings across a broad spectrum of packing fractions. Here we report that disordered strictly jammed binary packings (packings that remain mechanically stable under general shear deformations and compressions) can be produced with an anomalously large range of average packing fractions 0.634≤ϕ≤0.829 for small to large sphere radius ratios α restricted to α≥0.100. Surprisingly, this range of average packing fractions is obtained for packings containing a subset of spheres (called the backbone) that are exactly strictly jammed, exactly isostatic, and also generated from random initial conditions. Additionally, the average packing fractions of these packings at certain α and small sphere relative number concentrations x approach those of the corresponding densest known ordered packings. These findings suggest for entropic reasons that these high-density disordered packings should be good glass formers and that they may be easy to prepare experimentally. We also identify an unusual feature of the packing fraction of jammed backbones (packings with rattlers excluded). The backbone packing fraction is about 0.624 over the majority of the α-x plane, even when large numbers of small spheres are present in the backbone. Over the (relatively small) area of the α-x plane where the backbone is not roughly constant, we find that backbone packing fractions range from about 0.606 to 0.829, with the volume of rattler spheres comprising between 1.6% and 26.9% of total sphere volume. To generate isostatic strictly jammed packings, we use an implementation of the Torquato-Jiao sequential linear programming algorithm [Phys. Rev. EPLEEE81539-375510.1103/PhysRevE.82.061302 82, 061302 (2010)], which is an efficient producer of inherent structures (mechanically stable configurations at the local maxima in the density landscape). The identification and

  1. Disordered strictly jammed binary sphere packings attain an anomalously large range of densities.

    Science.gov (United States)

    Hopkins, Adam B; Stillinger, Frank H; Torquato, Salvatore

    2013-08-01

    Previous attempts to simulate disordered binary sphere packings have been limited in producing mechanically stable, isostatic packings across a broad spectrum of packing fractions. Here we report that disordered strictly jammed binary packings (packings that remain mechanically stable under general shear deformations and compressions) can be produced with an anomalously large range of average packing fractions 0.634≤φ≤0.829 for small to large sphere radius ratios α restricted to α≥0.100. Surprisingly, this range of average packing fractions is obtained for packings containing a subset of spheres (called the backbone) that are exactly strictly jammed, exactly isostatic, and also generated from random initial conditions. Additionally, the average packing fractions of these packings at certain α and small sphere relative number concentrations x approach those of the corresponding densest known ordered packings. These findings suggest for entropic reasons that these high-density disordered packings should be good glass formers and that they may be easy to prepare experimentally. We also identify an unusual feature of the packing fraction of jammed backbones (packings with rattlers excluded). The backbone packing fraction is about 0.624 over the majority of the α-x plane, even when large numbers of small spheres are present in the backbone. Over the (relatively small) area of the α-x plane where the backbone is not roughly constant, we find that backbone packing fractions range from about 0.606 to 0.829, with the volume of rattler spheres comprising between 1.6% and 26.9% of total sphere volume. To generate isostatic strictly jammed packings, we use an implementation of the Torquato-Jiao sequential linear programming algorithm [Phys. Rev. E 82, 061302 (2010)], which is an efficient producer of inherent structures (mechanically stable configurations at the local maxima in the density landscape). The identification and explicit construction of binary packings

  2. Radiation therapists' perceptions of the minimum level of experience required to perform portal image analysis

    International Nuclear Information System (INIS)

    Rybovic, Michala; Halkett, Georgia K.; Banati, Richard B.; Cox, Jennifer

    2008-01-01

    Background and purpose: Our aim was to explore radiation therapists' views on the level of experience necessary to undertake portal image analysis and clinical decision making. Materials and methods: A questionnaire was developed to determine the availability of portal imaging equipment in Australia and New Zealand. We analysed radiation therapists' responses to a specific question regarding their opinion on the minimum level of experience required for health professionals to analyse portal images. We used grounded theory and a constant comparative method of data analysis to derive the main themes. Results: Forty-six radiation oncology facilities were represented in our survey, with 40 questionnaires being returned (87%). Thirty-seven radiation therapists answered our free-text question. Radiation therapists indicated three main themes which they felt were important in determining the minimum level of experience: 'gaining on-the-job experience', 'receiving training' and 'working as a team'. Conclusions: Radiation therapists indicated that competence in portal image review occurs via various learning mechanisms. Further research is warranted to determine perspectives of other health professionals, such as radiation oncologists, on portal image review becoming part of radiation therapists' extended role. Suitable training programs and steps for implementation should be developed to facilitate this endeavour

  3. Nutritionally recommended food for semi- to strict vegetarian diets based on large-scale nutrient composition data.

    Science.gov (United States)

    Kim, Seunghyeon; Fenech, Michael F; Kim, Pan-Jun

    2018-03-12

    Diet design for vegetarian health is challenging due to the limited food repertoire of vegetarians. This challenge can be partially overcome by quantitative, data-driven approaches that utilise massive nutritional information collected for many different foods. Based on large-scale data of foods' nutrient compositions, the recent concept of nutritional fitness helps quantify a nutrient balance within each food with regard to satisfying daily nutritional requirements. Nutritional fitness offers prioritisation of recommended foods using the foods' occurrence in nutritionally adequate food combinations. Here, we systematically identify nutritionally recommendable foods for semi- to strict vegetarian diets through the computation of nutritional fitness. Along with commonly recommendable foods across different diets, our analysis reveals favourable foods specific to each diet, such as immature lima beans for a vegan diet as an amino acid and choline source, and mushrooms for ovo-lacto vegetarian and vegan diets as a vitamin D source. Furthermore, we find that selenium and other essential micronutrients can be subject to deficiency in plant-based diets, and suggest nutritionally-desirable dietary patterns. We extend our analysis to two hypothetical scenarios of highly personalised, plant-based methionine-restricted diets. Our nutrient-profiling approach may provide a useful guide for designing different types of personalised vegetarian diets.

  4. Lyme Neuroborreliosis: Preliminary Results from an Urban Referral Center Employing Strict CDC Criteria for Case Selection

    Directory of Open Access Journals (Sweden)

    David S. Younger

    2010-01-01

    Full Text Available Lyme neuroborreliosis or “neurological Lyme disease” was evidenced in 2 of 23 patients submitted to strict criteria for case selection of the Centers for Disease Control and Prevention employing a two-tier test to detect antibodies to Borrelia burgdorferi at a single institution. One patient had symptomatic polyradiculoneuritis, dysautonomia, and serological evidence of early infection; and another had symptomatic small fiber sensory neuropathy, distal polyneuropathy, dysautonomia, and serological evidence of late infection. In the remaining patients symptoms initially ascribed to Lyme disease were probably unrelated to B. burgdorferi infection. Our findings suggest early susceptibility and protracted involvement of the nervous system most likely due to the immunological effects of B. burgdorferi infection, although the exact mechanisms remain uncertain.

  5. On The Integral Representation of Strictly Continuous Set-Valued Maps

    Directory of Open Access Journals (Sweden)

    Anaté K. Lakmon

    2015-11-01

    Full Text Available Let T be a completely regular topological space and C(T be the space of bounded, continuous real-valued functions on T. C(T is endowed with the strict topology (the topology generated by seminorms determined by continuous functions vanishing at in_nity. R. Giles ([13], p. 472, Theorem 4.6 proved in 1971 that the dual of C(T can be identi_ed with the space of regular Borel measures on T. We prove this result for positive, additive set-valued maps with values in the space of convex weakly compact non-empty subsets of a Banach space and we deduce from this result the theorem of R. Giles ([13], theorem 4.6, p.473.

  6. A Total Variation Model Based on the Strictly Convex Modification for Image Denoising

    Directory of Open Access Journals (Sweden)

    Boying Wu

    2014-01-01

    Full Text Available We propose a strictly convex functional in which the regular term consists of the total variation term and an adaptive logarithm based convex modification term. We prove the existence and uniqueness of the minimizer for the proposed variational problem. The existence, uniqueness, and long-time behavior of the solution of the associated evolution system is also established. Finally, we present experimental results to illustrate the effectiveness of the model in noise reduction, and a comparison is made in relation to the more classical methods of the traditional total variation (TV, the Perona-Malik (PM, and the more recent D-α-PM method. Additional distinction from the other methods is that the parameters, for manual manipulation, in the proposed algorithm are reduced to basically only one.

  7. Residual diffeomorphisms and symplectic soft hairs: The need to refine strict statement of equivalence principle

    Science.gov (United States)

    Sheikh-Jabbari, M. M.

    2016-09-01

    General covariance is the cornerstone of Einstein’s general relativity (GR) and implies that any two metrics related by diffeomorphisms are physically equivalent. There are, however, many examples pointing to the fact that this strict statement of general covariance needs refinement. There are a very special (measure-zero) subset of diffeomorphisms, the residual diffeomorphisms, to which one can associate well-defined conserved charges. This would hence render these diffeomorphic geometries physically distinct. We discuss that these symmetries may be appropriately called “symplectic symmetries”. Existence of residual diffeomorphisms and symplectic symmetries can be a quite general feature and not limited to the examples discussed so far in the literature. We propose that, in the context of black holes, these diffeomorphic, but distinct, geometries may be viewed as “symplectic soft hair” on black holes. We comment on how this may remedy black hole microstate problem, which in this context are dubbed as “horizon fluffs”.

  8. Reactions to terror attacks in ultra-orthodox jews: the cost of maintaining strict identity.

    Science.gov (United States)

    Ankri, Yael L E; Bachar, Eytan; Shalev, Arieh Y

    2010-01-01

    Traumatic events can shatter faith and beliefs. The responses of Ultra-Orthodox survivors of deadly terrorist attacks illustrate an effort to reconcile dreadful experiences with deeply embedded beliefs. Qualified clinicians prospectively evaluated self-reported and interviewer-generated posttraumatic stress disorder (PTSD) symptoms and cognitive appraisal in Ultra-Orthodox (n = 20) and non-Ultra-Orthodox (n = 33) survivors of suicide bus-bombing incidents in Jerusalem. Ultra-Orthodox survivors reported higher levels of PTSD symptoms and more personal guilt. Their narratives reflected an unshaken belief in Just Providence, within which being a victim of terror was perceived as a Just retribution for known or unknown wrongdoing. Survivors' reactions to trauma often reflect an effort to reconcile incongruous experiences with previously held beliefs. When treating strict believers, helpers should be sensitive to the identity-preserving function of posttraumatic cognitions.

  9. On a class of adjustable rate mortgage loans subject to a strict balance principle

    DEFF Research Database (Denmark)

    Astrup Jensen, Bjarne

    We describe the background and the basic funding mechanisms for the type of adjustable rate mortgageloans that were introduced in the Danish market in 1996. Each loan is funded separately by tap issuingpass-through mortgage bonds (`strict balance principle'). The novelty is a funding mechanism...... that usesa roll-over strategy, where long term loans are funded by sequentially issuing short term pass-throughbonds, and the first issuer of these loans obtained a patent on the funding principles in 1999. Publiclyavailable descriptions of the principles leave an impression of very complicated numerical...... algorithms.The algorithms described here show that the essentials can be reduced to a `back of an envelope' complexity.Keywords: Adjustable rate mortgages, balance principle, patent, yield curve riding...

  10. Strict Liability Versus Policy and Regulation for Environmental Protection and Agricultural Waste Management in Malaysia

    Directory of Open Access Journals (Sweden)

    Mohd Bakri Ishak

    2010-01-01

    Full Text Available Basically, strict liability is part of the mechanism for expressing judgment or sentence by using direct evidence. This principle is very useful in order to obtain remedies from any damage either directly or indirectly. The principle in Rylands v Fletcher is responsible on imposing strict liability where if something brought onto land or collected there escapes liability under this rule can include not only the owner of land but also those who control or occupation on it. However, as a matter of fact, policy and regulation are also important in taking any action against any party who are responsible for environmental pollution or damage, which may include mismanagement of waste or industrial waste or agricultural waste. There are certain policies and regulations on environmental protection such as the National Environmental Policy, certain Acts and several regulations under the Environmental Quality Act 1974 (Act 127, which are very useful for agricultural waste management inter alia: Waters Act 1920 (Act 418, Environmental Quality (Prescribed Premises (Crude Palm Oil Regulations 1977, Environmental Quality (Prescribed Premises (Raw Natural Rubber Regulations 1978, Environmental Quality (Sewage and Industrial Effluents Regulations 1979, and Environmental Quality (Compounding of Offences Rules 1978. As a matter of fact, we should realize that time is of an essence for any parties which are involved in court cases and especially in avoiding the element of externality, which is commonly suffered by the government. In making this paper, therefore, some element of comparison with certain developed jurisdiction such as in the United Kingdom and Japan could not be avoided in order to obtain better outcome and to be more practical for the purpose of environmental protection and agricultural waste management.

  11. The Effect of Strict Segregation on Pseudomonas aeruginosa in Cystic Fibrosis Patients.

    Directory of Open Access Journals (Sweden)

    Rosa van Mansfeld

    Full Text Available Segregation of patients with cystic fibrosis (CF was implemented to prevent chronic infection with epidemic Pseudomonas aeruginosa strains with presumed detrimental clinical effects, but its effectiveness has not been carefully evaluated.The effect of strict segregation on the incidence of P. aeruginosa infection in CF patients was investigated through longitudinal protocolized follow-up of respiratory tract infection before and after segregation. In two nested cross-sectional studies in 2007 and 2011 the P. aeruginosa population structure was investigated and clinical parameters were determined in patients with and without infection with the Dutch epidemic P. aeruginosa clone (ST406.Of 784 included patients 315 and 382 were at risk for acquiring chronic P. aeruginosa infection before and after segregation. Acquisition rates were, respectively, 0.14 and 0.05 per 1,000 days at risk (HR: 0.66, 95% CI [0.2548-1.541]; p = 0.28. An exploratory subgroup analysis indicated lower acquisition after segregation in children < 15 years of age (HR: 0.43, 95% CI[0.21-0.95]; p = 0.04. P. aeruginosa population structure did not change after segregation and ST406 was not associated with lung function decline, death or lung transplantation.Strict segregation was not associated with a statistically significant lower acquisition of chronic P. aeruginosa infection and ST406 was not associated with adverse clinical outcome. After segregation there were no new acquisitions of ST406. In an unplanned exploratory analysis chronic acquisition of P. aeruginosa was lower after implementation of segregation in patients under 15 years of age.

  12. Weight of fitness deviation governs strict physical chaos in replicator dynamics

    Science.gov (United States)

    Pandit, Varun; Mukhopadhyay, Archan; Chakraborty, Sagar

    2018-03-01

    Replicator equation—a paradigm equation in evolutionary game dynamics—mathematizes the frequency dependent selection of competing strategies vying to enhance their fitness (quantified by the average payoffs) with respect to the average fitnesses of the evolving population under consideration. In this paper, we deal with two discrete versions of the replicator equation employed to study evolution in a population where any two players' interaction is modelled by a two-strategy symmetric normal-form game. There are twelve distinct classes of such games, each typified by a particular ordinal relationship among the elements of the corresponding payoff matrix. Here, we find the sufficient conditions for the existence of asymptotic solutions of the replicator equations such that the solutions—fixed points, periodic orbits, and chaotic trajectories—are all strictly physical, meaning that the frequency of any strategy lies inside the closed interval zero to one at all times. Thus, we elaborate on which of the twelve types of games are capable of showing meaningful physical solutions and for which of the two types of replicator equation. Subsequently, we introduce the concept of the weight of fitness deviation that is the scaling factor in a positive affine transformation connecting two payoff matrices such that the corresponding one-shot games have exactly same Nash equilibria and evolutionary stable states. The weight also quantifies how much the excess of fitness of a strategy over the average fitness of the population affects the per capita change in the frequency of the strategy. Intriguingly, the weight's variation is capable of making the Nash equilibria and the evolutionary stable states, useless by introducing strict physical chaos in the replicator dynamics based on the normal-form game.

  13. Strict stoichiometric homeostasis of Cryptomonas pyrenoidifera (Cryptophyceae in relation to N:P supply ratios

    Directory of Open Access Journals (Sweden)

    Eloísa Ramos Rodríguez

    2016-11-01

    Full Text Available A common freshwater cryptophyte, Cryptomonas pyrenoidifera, was cultivated in batch-cultures to analyze intraspecific variation in elemental stoichiometry along a broad gradient of pulsed phosphorus (P enrichment during the early acclimation period and to determine the immediate homeostatic capacity of the nitrogen-to-phosphorus (N:P ratio of this alga when nutrients are at saturating levels. Experimental results revealed that nitrogen (N and P cell quotas significantly increased with increasing P concentration. However, despite the wide range of N:P ratios in the medium, Cryptomonas N:P ratios were highly stable at higher P-level treatments, indicating a highly conservative behavior and suggesting strict elemental homeostasis when nutrients are at saturating levels. The strictly homeostatic N:P ratio appears to be attributable to their high potential for a fast luxury consumption of both N and P after a brief and intense episode of increased resource availability and to physiological limits on their nutrient storage capacity. Most importantly, the N:P biomass ratio at nutrient saturating levels converged around 11:1, which was the observed ratio of maximum internal cell quotas for N and P (i.e. Qmax,N:Qmax,P under the prevailing experimental conditions. This value is particularly informative for C. pyrenoidifera because it represents cell storage quotients and may be a taxon-specific evolutionary optimum, providing a reference point to infer the grade of nutrient-limitation. The experimental data give ranges of variation in C. pyrenoidifera elemental composition permitting, among others, proper parameterization of cryptophyte stoichiometry models.

  14. Overview of the Design, Fabrication and Performance Requirements of Micro-Spec, an Integrated Submillimeter Spectrometer

    Science.gov (United States)

    Barrentine, Emily M.; Noroozian, Omid; Brown, Ari D.; Cataldo, Giuseppe; Ehsan, Negar; Hsieh, Wen-Ting; Stevenson, Thomas R.; U-Yen, Kongpop; Wollack, Edward J.; Moseley, S. Harvey

    2015-01-01

    Micro-Spec is a compact submillimeter (350-700 GHz) spectrometer which uses low loss superconducting niobium microstrip transmission lines and a single-crystal silicon dielectric to integrate all of the components of a grating-analog spectrometer onto a single chip. Here we present details of the fabrication and design of a prototype Micro-Spec spectrometer with resolution, R64, where we use a high-yield single-flip wafer bonding process to realize instrument components on a 0.45 m single-crystal silicon dielectric. We discuss some of the electromagnetic design concerns (such as loss, stray-light, cross-talk, and fabrication tolerances) for each of the spectrometer components and their integration into the instrument as a whole. These components include a slot antenna with a silicon lens for optical coupling, a phase delay transmission line network, parallel plate waveguide interference region, and aluminum microstrip transmission line kinetic inductance detectors with extremely low cross-talk and immunity to stray light. We have demonstrated this prototype spectrometer with design resolution of R64. Given the optical performance of this prototype, we will also discuss the extension of this design to higher resolutions suitable for balloon-flight.

  15. Strict follow-up programme including CT and (18) F-FDG-PET after curative surgery for colorectal cancer

    DEFF Research Database (Denmark)

    Sørensen, N F; Jensen, A B; Wille-Jørgensen, P

    2010-01-01

    Aim  The risk of local recurrence following curative surgery for colorectal cancer (CRC) is up to 50%. A rigorous follow-up program may increase survival. Guidelines on suitable methods for scheduled follow up examinations are needed. This study evaluates a strict follow-up program including...... supported a strict follow-up program following curative surgery for colorectal cancer. FDG-PET combined with CT should be included in control programs....

  16. Preliminary Test Requirements for the Performance Test of Passive Decay Heat Removal System of Sodium-Cooled Fast Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Tae Ho; Kwon, Young Min; Kim, Tae Joon; Eoh, Jae Hyuk; Lee, Yong Bum; Ha, Kwi Seok; Hwang, In Koo

    2009-06-15

    In order to verify the concept of safety grade passive decay removal system PDRC (Passive Decay heat Removal Circuit) of KALIMER-600 and the design features to resolve the design issues for securing the cooling performance, the performance test is implemented. In this report, the preliminary test requirements for using as a guideline to the design of the experimental facility were established. Since the experimental facility should be designed so as to simulate the various thermal- hydraulic phenomena, as closely as possible, to be occurred in reference reactor during the decay heat removal operation, the design characteristics of the reference reactor (KALIMER-600) were analyzed for drawing major constitutive elements to be simulated in the facility. The preliminary test matrix was set up by the analysis of various design basis events and then the key test matrix was determined. Also, the priority for various thermal hydraulic phenomena which should be considered in the design of the experimental facility was determined by analyzing the phenomena for each key test matrix. Based on the analysis, the general design requirements for experimental facility were prepared and the design requirements for fluid systems and instrumentation were established. The test requirements in this report will be reflected in the scaling analysis and the basic design of the experimental facility. The test matrix specified in this report can be modified in the stage of main testing by considering the needs of experiments and circumstances at that time.

  17. Intra-Genomic Heterogeneity in 16S rRNA Genes in Strictly Anaerobic Clinical Isolates from Periodontal Abscesses

    Science.gov (United States)

    Chen, Jiazhen; Miao, Xinyu; Xu, Meng; He, Junlin; Xie, Yi; Wu, Xingwen; Chen, Gang; Yu, Liying; Zhang, Wenhong

    2015-01-01

    Background Members of the genera Prevotella, Veillonella and Fusobacterium are the predominant culturable obligate anaerobic bacteria isolated from periodontal abscesses. When determining the cumulative number of clinical anaerobic isolates from periodontal abscesses, ambiguous or overlapping signals were frequently encountered in 16S rRNA gene sequencing chromatograms, resulting in ambiguous identifications. With the exception of the genus Veillonella, the high intra-chromosomal heterogeneity of rrs genes has not been reported. Methods The 16S rRNA genes of 138 clinical, strictly anaerobic isolates and one reference strain were directly sequenced, and the chromatograms were carefully examined. Gene cloning was performed for 22 typical isolates with doublet sequencing signals for the 16S rRNA genes, and four copies of the rrs-ITS genes of 9 Prevotella intermedia isolates were separately amplified by PCR, sequenced and compared. Five conserved housekeeping genes, hsp60, recA, dnaJ, gyrB1 and rpoB from 89 clinical isolates of Prevotella were also amplified by PCR and sequenced for identification and phylogenetic analysis along with 18 Prevotella reference strains. Results Heterogeneity of 16S rRNA genes was apparent in clinical, strictly anaerobic oral bacteria, particularly in the genera Prevotella and Veillonella. One hundred out of 138 anaerobic strains (72%) had intragenomic nucleotide polymorphisms (SNPs) in multiple locations, and 13 strains (9.4%) had intragenomic insertions or deletions in the 16S rRNA gene. In the genera Prevotella and Veillonella, 75% (67/89) and 100% (19/19) of the strains had SNPs in the 16S rRNA gene, respectively. Gene cloning and separate amplifications of four copies of the rrs-ITS genes confirmed that 2 to 4 heterogeneous 16S rRNA copies existed. Conclusion Sequence alignment of five housekeeping genes revealed that intra-species nucleotide similarities were very high in the genera Prevotella, ranging from 94.3–100%. However, the

  18. Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight: a randomized controlled clinical trial.

    Science.gov (United States)

    Weidlich, Patricia; Moreira, Carlos Heitor C; Fiorini, Tiago; Musskopf, Marta L; da Rocha, José M; Oppermann, Maria Lucia R; Aass, Anne M; Gjermo, Per; Susin, Cristiano; Rösing, Cassiano K; Oppermann, Rui V

    2013-01-01

    This randomized controlled clinical trial was carried out to assess the effect of comprehensive nonsurgical periodontal treatment and strict plaque control performed during pregnancy on the reduction of preterm and/or low birth weight rates (PTLBW). Three hundred and three women were randomly allocated to receive periodontal treatment either during pregnancy (n = 147, test group) or after delivery (n = 156, control group). During pregnancy, the control group received only one session of supragingival scaling and oral hygiene instruction. In contrast, the test group received comprehensive periodontal treatment including multiple sessions of scaling and root planing, oral hygiene instructions, and frequent maintenance visits. At baseline, periodontal inflammation was observed in approximately 50% of sites and attachment loss affected controls, women in the test group had significant reductions in the percentage of sites with plaque (48.5% vs. 10.3%, p control significantly improved periodontal health; however, no reduction of PTLBW rates was observed. Thus, remaining periodontal inflammation posttreatment cannot explain the lack of effect of periodontal treatment on PTLBW. Clinical relevance This study demonstrated that periodontal diseases may be successfully treated during pregnancy. Our results do not support a potential beneficial effect of periodontal treatment on PTLBW.

  19. SHARP's systems engineering challenge: rectifying integrated product team requirements with performance issues in an evolutionary spiral development acquisition

    Science.gov (United States)

    Kuehl, C. Stephen

    2003-08-01

    Completing its final development and early deployment on the Navy's multi-role aircraft, the F/A-18 E/F Super Hornet, the SHAred Reconnaissance Pod (SHARP) provides the war fighter with the latest digital tactical reconnaissance (TAC Recce) Electro-Optical/Infrared (EO/IR) sensor system. The SHARP program is an evolutionary acquisition that used a spiral development process across a prototype development phase tightly coupled into overlapping Engineering and Manufacturing Development (EMD) and Low Rate Initial Production (LRIP) phases. Under a tight budget environment with a highly compressed schedule, SHARP challenged traditional acquisition strategies and systems engineering (SE) processes. Adopting tailored state-of-the-art systems engineering process models allowd the SHARP program to overcome the technical knowledge transition challenges imposed by a compressed program schedule. The program's original goal was the deployment of digital TAC Recce mission capabilities to the fleet customer by summer of 2003. Hardware and software integration technical challenges resulted from requirements definition and analysis activities performed across a government-industry led Integrated Product Team (IPT) involving Navy engineering and test sites, Boeing, and RTSC-EPS (with its subcontracted hardware and government furnished equipment vendors). Requirements development from a bottoms-up approach was adopted using an electronic requirements capture environment to clarify and establish the SHARP EMD product baseline specifications as relevant technical data became available. Applying Earned-Value Management (EVM) against an Integrated Master Schedule (IMS) resulted in efficiently managing SE task assignments and product deliveries in a dynamically evolving customer requirements environment. Application of Six Sigma improvement methodologies resulted in the uncovering of root causes of errors in wiring interconnectivity drawings, pod manufacturing processes, and avionics

  20. On the “cost-optimal levels” of energy performance requirements and its economic evaluation in Italy

    Directory of Open Access Journals (Sweden)

    Lamberto Tronchin

    2014-10-01

    Full Text Available The European energy policies about climate and energy package, known as the “20-20-20” targets define ambitious, but achievable, national energy objectives. As regards the Directives closely related to the 2020 targets, the EU Energy Performance of Buildings Directive (EPBD Recast- DIR 2010/31/EU is the main European legislative instrument for improving the energy performance of buildings, taking into account outdoor climatic and local conditions, as well as indoor climate requirements and cost-effectiveness. The EPBD recast now requests that Member States shall ensure that minimum energy performance requirements for buildings are set “with a view to achieving cost-optimal levels”. The cost optimum level shall be calculated in accordance with a comparative methodology framework, leaving the Member States to determine which of these calculations is to become the national benchmark against which national minimum energy performance requirements will be assessed. The European standards (ENs- Umbrella Document V7 (prCEN/TR 15615 are intended to support the EPBD by providing the calculation methods and associated material to obtain the overall energy performance of a building. For Italy the Energy Performance of Building Simulations EPBS must be calculated with standard UNITS 11300. The energy building behaviour is referred to standard and not to real use, nor climate or dynamic energy evaluation. Since retrofitting of existing buildings offers significant opportunities for reducing energy consumption and greenhouse gas emissions, a case study of retrofitting is described and the CostOptimal Level EU procedure in an Italian context is analysed. Following this procedure, it is shown not only that the energy cost depends on several conditions and most of them are not indexed at national level but also that the cost of improvement depends on local variables and contract tender. The case study highlights the difficulties to apply EU rules, and

  1. Army Sociocultural Performance Requirements

    Science.gov (United States)

    2014-06-01

    please see Pulakos, E.D., Arad, S., Donovan, M.A., Plamondon, K.E. (2000). Adaptability in the workplace : Development of a taxonomy of adaptive...actions within multicultural settings is integrated into the existing material. This could be done as needed for enlisted Soldiers (leader cross...describe specific actions that Soldiers may need to accomplish while deployed in a multicultural setting. Trends in the data informed recommendations

  2. Managing curriculum transformation within strict university governance structures: an example from Damascus University Medical School.

    Science.gov (United States)

    Kayyal, Mohammad; Gibbs, Trevor

    2012-01-01

    As the world of medical education moves forward, it becomes increasingly clear that the transformative process is not as easy a process for all. Across the globe, there appears to be many barriers that obstruct or threaten innovation and change, most of which cause almost insurmountable problems to many schools. If transformative education is to result in an equitable raising of standards across such an unlevel playing field, schools have to find ways in overcoming these barriers. One seemingly common barrier to development occurs when medical schools are trapped within strict University governance structures; rules and regulations which are frequently inappropriate and obstructive to the transformation that must occur in today's medical educational paradigm. The Faculty of Medicine at Damascus University, one of the oldest and foremost medical schools in the Middle East, is one such school where rigid rules and regulations and traditional values are obstructing transformative change. This paper describes the problems, which the authors believe to be common to many, and explores how attempts have been made to overcome them and move the school into the twenty-first century. It is the ultimate purpose of this paper to raise awareness of the issue, share the lessons learned in order to assist others who are experiencing similar problems and possibly create opportunities for dialogue between schools.

  3. On a holomorphic Lefschetz formula in strictly pseudoconvex subdomains of complex manifolds

    International Nuclear Information System (INIS)

    Kytmanov, A M; Myslivets, S G; Tarkhanov, N N

    2004-01-01

    The classical Lefschetz formula expresses the number of fixed points of a continuous map f:M→M in terms of the transformation induced by f on the cohomology of M. In 1966, Atiyah and Bott extended this formula to elliptic complexes over a compact closed manifold. In particular, they obtained a holomorphic Lefschetz formula on compact complex manifolds without boundary. Brenner and Shubin (1981, 1991) extended the Atiyah-Bott theory to compact manifolds with boundary. On compact complex manifolds with boundary the Dolbeault complex is not elliptic, therefore the Atiyah-Bott theory is not applicable. Bypassing difficulties related to the boundary behaviour of Dolbeault cohomology, Donnelly and Fefferman (1986) obtained a formula for the number of fixed points in terms of the Bergman metric. The aim of this paper is to obtain a Lefschetz formula on relatively compact strictly pseudoconvex subdomains of complex manifolds X with smooth boundary, that is, to find the total Lefschetz number for a holomorphic endomorphism f * of the Dolbeault complex and to express it in terms of local invariants of the fixed points of f.

  4. Divergent changes in serum sterols during a strict uncooked vegan diet in patients with rheumatoid arthritis.

    Science.gov (United States)

    Agren, J J; Tvrzicka, E; Nenonen, M T; Helve, T; Hänninen, O

    2001-02-01

    The effects of a strict uncooked vegan diet on serum lipid and sterol concentrations were studied in patients with rheumatoid arthritis. The subjects were randomized into a vegan diet group (n 16), who consumed a vegan diet for 2-3 months, or into a control group (n 13), who continued their usual omnivorous diets. Serum total and LDL-cholesterol and -phospholipid concentrations were significantly decreased by the vegan diet. The levels of serum cholestanol and lathosterol also decreased, but serum cholestanol:total cholesterol and lathosterol:total cholesterol did not change. The effect of a vegan diet on serum plant sterols was divergent as the concentration of campesterol decreased while that of sitosterol increased. This effect resulted in a significantly greater sitosterol:campesterol value in the vegan diet group than in the control group (1.48 (SD 0.39) v. 0.72 (SD 0.14); P vegan diet changes the relative absorption rates of these sterols and/or their biliary clearance.

  5. Model-Based Adaptive Event-Triggered Control of Strict-Feedback Nonlinear Systems.

    Science.gov (United States)

    Li, Yuan-Xin; Yang, Guang-Hong

    2018-04-01

    This paper is concerned with the adaptive event-triggered control problem of nonlinear continuous-time systems in strict-feedback form. By using the event-sampled neural network (NN) to approximate the unknown nonlinear function, an adaptive model and an associated event-triggered controller are designed by exploiting the backstepping method. In the proposed method, the feedback signals and the NN weights are aperiodically updated only when the event-triggered condition is violated. A positive lower bound on the minimum intersample time is guaranteed to avoid accumulation point. The closed-loop stability of the resulting nonlinear impulsive dynamical system is rigorously proved via Lyapunov analysis under an adaptive event sampling condition. In comparing with the traditional adaptive backstepping design with a fixed sample period, the event-triggered method samples the state and updates the NN weights only when it is necessary. Therefore, the number of transmissions can be significantly reduced. Finally, two simulation examples are presented to show the effectiveness of the proposed control method.

  6. DNA remodelling by Strict Partial Endoreplication in orchids, an original process in the plant kingdom.

    Science.gov (United States)

    Brown, Spencer C; Bourge, Mickaël; Maunoury, Nicolas; Wong, Maurice; Bianchi, Michele Wolfe; Lepers-Andrzejewski, Sandra; Besse, Pascale; Siljak-Yakovlev, Sonja; Dron, Michel; Satiat-Jeunemaître, Béatrice

    2017-04-13

    DNA remodelling during endoreplication appears to be a strong developmental characteristic in orchids. In this study, we analysed DNA content and nuclei in 41 species of orchids to further map the genome evolution in this plant family. We demonstrate that the DNA remodelling observed in 36 out of 41 orchids studied corresponds to strict partial endoreplication. Such process is developmentally regulated in each wild species studied. Cytometry data analyses allowed us to propose a model where nuclear states 2C, 4E, 8E, etc. form a series comprising a fixed proportion, the euploid genome 2C, plus 2 to 32 additional copies of a complementary part of the genome. The fixed proportion ranged from 89% of the genome in Vanilla mexicana down to 19% in V. pompona, the lowest value for all 148 orchids reported. Insterspecific hybridisation did not suppress this phenomenon. Interestingly, this process was not observed in mass-produced epiphytes. Nucleolar volumes grow with the number of endocopies present, coherent with high transcription activity in endoreplicated nuclei. Our analyses suggest species-specific chromatin rearrangement. Towards understanding endoreplication, V. planifolia constitutes a tractable system for isolating the genomic sequences that confer an advantage via endoreplication from those that apparently suffice at diploid level. © The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  7. Generalized mechanical pain sensitivity over nerve tissues in patients with strictly unilateral migraine.

    Science.gov (United States)

    Fernández-de-las-Peñas, César; Arendt-Nielsen, Lars; Cuadrado, María Luz; Pareja, Juan A

    2009-06-01

    No study has previously analyzed pressure pain sensitivity of nerve trunks in migraine. This study aimed to examine the differences in mechanical pain sensitivity over specific nerves between patients with unilateral migraine and healthy controls. Blinded investigators assessed pressure pain thresholds (PPT) over the supra-orbital nerves (V1) and peripheral nerve trunks of both upper extremities (median, radial, and ulnar nerves) in 20 patients with strictly unilateral migraine and 20 healthy matched controls. Pain intensity after palpation over both supra-orbital nerves was also assessed. A pressure algometer was used to quantify PPT, whereas a 10-point numerical pain rate scale was used to evaluate pain to palpation over the supra-orbital nerve. The analysis of covariance revealed that pain to palpation over the supra-orbital nerve was significantly higher (P0.6). In patients with unilateral migraine, we found increased mechano-sensitivity of the supra-orbital nerve on the symptomatic side of the head. Outside the head, the same patients showed increased mechano-sensitivity of the main peripheral nerves of both upper limbs, without asymmetries. Such diffuse hypersensitivity of the peripheral nerves lends further evidence to the presence of a state of hyperexcitability of the central nervous system in patients with unilateral migraine.

  8. Changes in Frequency Intake of Foods in Patients Undergoing Sleeve Gastrectomy and Following a Strict Dietary Control.

    Science.gov (United States)

    Ruiz-Tovar, Jaime; Bozhychko, Maryana; Del-Campo, Jone Miren; Boix, Evangelina; Zubiaga, Lorea; Muñoz, Jose Luis; Llavero, Carolina

    2017-12-17

    Dietary intake and food preferences change after bariatric surgery, secondary to gastrointestinal symptoms and dietitian counseling. The aim of this study was to evaluate the changes in the frequency intake of different foods in patients undergoing sleeve gastrectomy and following a strict dietary control. A prospective observational study of all the morbidly obese patients undergoing laparoscopic sleeve gastrectomy as bariatric procedure between 2007 and 2012 was performed. Dietary assessment was performed using the Alimentary Frequency Questionnaire 1991-2002, developed and validated by the Department of Epidemiology of Miguel Hernandez University (Elche, Alicante Spain). Ninety-three patients were included for analysis, 73 females and 20 males, with a mean preoperative BMI of 46.4 ± 7.9 kg/m 2 . One year after surgery, excess weight loss was 81.1 ± 8.3% and 5 years after surgery, 79.9 ± 6.4%. Total weight loss at 1 year was 38.8 ± 5.3% and at 5 years, 35.4 ± 4.9%. Postoperatively, a reduction in the intake of dairy products, red meat, deli meat products, shellfish, fried potatoes, sweets, rice, pasta, beer, and processed foods was observed. Vegetables, fruits, and legumes intake increased after surgery. In the first postoperative year, there was a slight intolerance to red meat, fruits, vegetables and legumes, dairy products, pasta, and rice that mostly disappeared 5 years after surgery. One year after sleeve gastrectomy, calibrated with a 50-French bougie, there are not important problems in the intake of foods a priori difficult to digest. These problems mostly disappeared 5 years after surgery. The decrease intake of other unhealthy foods is mostly based on the dietary counseling.

  9. Multi-Stage ADRs for Current and Future Astronomy Missions: Performance and Requirements for Cryogen-Free Operation

    Science.gov (United States)

    Shirron, Peter; Kimball, Mark; Vlahacos, Kosta

    2010-01-01

    The cooling requirements for current (e.g. Astro-H) and future (e.g. IXO and ASP) astronomy missions pose significant challenges for the sub-Kelvin Cooler. In particular, the use of large detector arrays increases the cooling power needed, and the variety of cryocoolers that can be used for pre-cooling greatly expands the range of temperatures at which the sub-Kelvin cooler can be designed to reject heat. In most cases, there is also a need for a stable higher temperature stage for cooling amplifiers or telescope components. NASA/GSFC is currently building a 3-stage ADR for the Astro-H mission, and is developing a 5-stage ADR suitable for IXO and ASP, as well as many other missions in the early planning stages. The architecture of these ADRs allows them to be adapted rather easily for different cooling requirements and to accommodate different cryocooler capabilities (operating temperature and cooling power). This paper will discuss the performance of these ADRs, which operate in both continuous, and single-shot cooling modes, and the minimum cryocooler capabilities needed to meet the requirements of future missions.

  10. Organic market gardening around the Paris agglomeration: agro-environmental performance and capacity to meet urban requirements.

    Science.gov (United States)

    Anglade, Juliette; Medina, Michael Ramos; Billen, Gilles; Garnier, Josette

    2016-05-04

    Organic market gardening is often promoted by urban municipalities as a way to resource part of the food supply, creating new social links and protecting groundwater resources. The agronomical and environmental performance of six commercial organic market gardening farms supplying vegetables in Paris were evaluated and compared with other vegetable production systems. When expressed in terms of protein production, the yield of these systems appears rather low compared with the productive capacity of open-field organic cropping systems where vegetable production is inserted into rotation with other crops. Moreover, the requirement of producing infiltrated water meeting the drinking water standards seriously limits the allowable rate of fertilisation, thus limiting production. The data reported herein show that to supply the amount of vegetables required by the Paris agglomeration (12 million inhabitants) only by organic market gardening, 160,000-205,000 ha, i.e. 28-36 % of the agricultural area of the surrounding Ile-de-France region, would be required. We conclude that organic market gardening is only one of several other farming systems which can contribute to a re-localised supply of vegetables to large cities.

  11. Thermosetting polyimide resin matrix composites with interpenetrating polymer networks for precision foil resistor chips based on special mechanical performance requirements

    International Nuclear Information System (INIS)

    Wang, X.Y.; Ma, J.X.; Li, C.G.; Wang, H.X.

    2014-01-01

    Highlights: • Macromolecular materials were chosen to modify thermosetting polyimide (TSPI). • The formation of IPN structure in TSPI composite polymers was discussed. • The special mechanical properties required were the main study object. • The desired candidate materials should have proper hardness and toughness. • The specific mechanical data are quantitatively determined by experiments. - Abstract: Based on interpenetrating networks (IPNs) different macromolecular materials such as epoxy, phenolic, and silicone resin were chosen to modify thermosetting polyimide (TSPI) resin to solve the lack of performance when used for protecting precision foil resistor chips. Copolymerization modification, controlled at curing stage, was used to prepare TSPI composites considering both performance and process requirements. The mechanical properties related to trimming process were mainly studied due to the special requirements of the regularity of scratch edges caused by a tungsten needle. The analysis on scratch edges reveals that the generation and propagation of microcracks caused by scratching together with crack closure effect may lead to regular scratch traces. Experiments show that the elongation at break of TSPI composites is the main reason that determines the special mechanical properties. The desired candidate materials should have proper hardness and toughness, and the specific mechanical data are that the mean elongation at break and tensile strength of polymer materials are in the range of 9.2–10.4% and 100–107 MPa, respectively. Possible reasons for the effect of the modifiers chosen on TSPI polymers, the reaction mechanisms on modified TSPI resin and the IPN structure in TSPI composite polymers were discussed based on IR and TG analysis

  12. Thermosetting polyimide resin matrix composites with interpenetrating polymer networks for precision foil resistor chips based on special mechanical performance requirements

    Energy Technology Data Exchange (ETDEWEB)

    Wang, X.Y., E-mail: wxy@tju.edu.cn [School of Electronic Information Engineering, Tianjin University, Tianjin 300072 (China); Ma, J.X.; Li, C.G. [School of Electronic Information Engineering, Tianjin University, Tianjin 300072 (China); Wang, H.X. [ZHENGHE electronics Co., Ltd, Jining 272023 (China)

    2014-04-01

    Highlights: • Macromolecular materials were chosen to modify thermosetting polyimide (TSPI). • The formation of IPN structure in TSPI composite polymers was discussed. • The special mechanical properties required were the main study object. • The desired candidate materials should have proper hardness and toughness. • The specific mechanical data are quantitatively determined by experiments. - Abstract: Based on interpenetrating networks (IPNs) different macromolecular materials such as epoxy, phenolic, and silicone resin were chosen to modify thermosetting polyimide (TSPI) resin to solve the lack of performance when used for protecting precision foil resistor chips. Copolymerization modification, controlled at curing stage, was used to prepare TSPI composites considering both performance and process requirements. The mechanical properties related to trimming process were mainly studied due to the special requirements of the regularity of scratch edges caused by a tungsten needle. The analysis on scratch edges reveals that the generation and propagation of microcracks caused by scratching together with crack closure effect may lead to regular scratch traces. Experiments show that the elongation at break of TSPI composites is the main reason that determines the special mechanical properties. The desired candidate materials should have proper hardness and toughness, and the specific mechanical data are that the mean elongation at break and tensile strength of polymer materials are in the range of 9.2–10.4% and 100–107 MPa, respectively. Possible reasons for the effect of the modifiers chosen on TSPI polymers, the reaction mechanisms on modified TSPI resin and the IPN structure in TSPI composite polymers were discussed based on IR and TG analysis.

  13. Strict Host-Symbiont Cospeciation and Reductive Genome Evolution in Insect Gut Bacteria

    Science.gov (United States)

    Hosokawa, Takahiro; Kikuchi, Yoshitomo; Nikoh, Naruo; Shimada, Masakazu; Fukatsu, Takema

    2006-01-01

    Host-symbiont cospeciation and reductive genome evolution have been identified in obligate endocellular insect symbionts, but no such example has been identified from extracellular ones. Here we first report such a case in stinkbugs of the family Plataspidae, wherein a specific gut bacterium is vertically transmitted via “symbiont capsule.” In all of the plataspid species, females produced symbiont capsules upon oviposition and their gut exhibited specialized traits for capsule production. Phylogenetic analysis showed that the plataspid symbionts constituted a distinct group in the γ-Proteobacteria, whose sister group was the aphid obligate endocellular symbionts Buchnera. Removal of the symbionts resulted in retarded growth, mortality, and sterility of the insects. The host phylogeny perfectly agreed with the symbiont phylogeny, indicating strict host-symbiont cospeciation despite the extracellular association. The symbionts exhibited AT-biased nucleotide composition, accelerated molecular evolution, and reduced genome size, as has been observed in obligate endocellular insect symbionts. These findings suggest that not the endocellular conditions themselves but the population genetic attributes of the vertically transmitted symbionts are probably responsible for the peculiar genetic traits of these insect symbionts. We proposed the designation “Candidatus Ishikawaella capsulata” for the plataspid symbionts. The plataspid stinkbugs, wherein the host-symbiont associations can be easily manipulated, provide a novel system that enables experimental approaches to previously untouched aspects of the insect-microbe mutualism. Furthermore, comparative analyses of the sister groups, the endocellular Buchnera and the extracellular Ishikawaella, would lead to insights into how the different symbiotic lifestyles have affected their genomic evolution. PMID:17032065

  14. Feed evaluation, nitrogen requirements and the effect of supplementary feeding on the performance of small ruminants in Cyprus

    International Nuclear Information System (INIS)

    Hadjipanayiotou, M.

    1988-01-01

    Experiments were carried out to evaluate the quality of various sources of roughage available in Cyprus as well as to determine the protein requirements of milk producing sheep and goats. Throughout the experimental programme comparisons were made between sheep and goats. A range of gramineous and leguminous hays were fed to Chios sheep in order to measure the digestibility of different constituents and digestible energy values. These hays were analysed chemically and digestibility was estimated in vitro. The leguminous hays were of higher digestibility (66.5%) than the gramineous (57.0%) despite having higher concentrations of acid detergent lignin (5.95 vs. 3.55%). There was good correlation between in vivo and in vitro measurements of digestibility. A series of experiments was conducted to measure various aspects of protein quality and requirements for production. In field trials, grazing goats were fed supplements of barley with or without a protein/mineral supplement. The inclusion of the protein/mineral supplement improved performance in suckling goats but not during pregnancy or mid-lactation. The mean retention time of protein in the rumen of lactating and dry ewes and goats was estimated using Cr-labelled soybean meal. Effective digestibility values (degradability values related to outflow rates) were similar in the two species, but were greater in lactating than dry animals. The requirements for protein in dairy goats were determined at various stages of lactation. In early lactation approximately 140 g CP/kg feed DM were required compared to around 100 g in late lactation. Two sources of protein, soybean and fishmeal, were compared in diets for ewes and goats. Significantly higher milk production was observed in ewes fed fishmeal but not in goats. (author). 29 refs, 9 tabs

  15. Entry qualifications and academic performance of architecture students in Nigerian Polytechnics: Are the admission requirements still relevant?

    Directory of Open Access Journals (Sweden)

    Peter O Adewale

    2014-03-01

    Full Text Available The competence of fresh graduates of architecture has been continuously criticized by the industry for inadequate knowledge. This is often blamed on the poor standard of education evidenced by poor performances in professional and degree/diploma examinations conducted by various schools of architecture in the country. Although, factors responsible for the scenario are well documented in the literature, most of these works are based on testimonial and circumstantial evidences relating to management of architectural education only. The aim of this paper is to investigate the relationship between entry qualifications and the performance of architecture students in Nigerian Polytechnics with a view to determining the relevance of current admission policy to architectural education in Nigeria. Data were obtained from official records in the Department of Architecture in four randomly selected polytechnics in the southwestern part of Nigeria. Pearson Product Moment Correlation (r was used to test the hypotheses. Findings reveal weak relationship between the two variables (physics and mathematics. This is contrary to the expectations of most scholars and policy makers who opine that students' proficiency in these subjects would enhance their performance at higher levels. The paper traces the contradiction to the poor handling of public examinations and misconception of architecture as being pure science. It holds that if these requirements are still relied upon for the admission of students into schools of architecture, wrong candidates would continue to gain entry into the profession. The paper concludes by recommending certain measures that are capable of reversing the trend.

  16. Analyses des discours non strictement mathematiques accompagnant des cours de mathematiques (Analysis of Not Strictly Mathematical Discourse in Mathematics Classes).

    Science.gov (United States)

    Robert, Aline

    1995-01-01

    Examines discourse, not strictly mathematical, that teachers might adopt in a mathematics class and presents three major functions of such discourse: communication; structuring and labeling; and reflection. Develops lines for further inquiry, notably on the third function, the most likely focus for specific preparation by the teacher. (13…

  17. Properties of N-person axiomatic bargaining solutions if the Pareto frontier is twice differentiable and strictly concave

    NARCIS (Netherlands)

    Douven, R.C.M.H.; Engwerda, J.C.

    1995-01-01

    In this paper we discuss properties of N-person axiomatic bargaining problems, where the Pareto frontier of S can be described by a strictly concave and twice differentiable function. These type of problems are characteristic for the empirical policy coordination literature. In that literature the

  18. Convergence of Implicit and Explicit Schemes for an Asymptotically Nonexpansive Mapping in -Uniformly Smooth and Strictly Convex Banach Spaces

    Directory of Open Access Journals (Sweden)

    Meng Wen

    2012-01-01

    Full Text Available We introduce a new iterative scheme with Meir-Keeler contractions for an asymptotically nonexpansive mapping in -uniformly smooth and strictly convex Banach spaces. We also proved the strong convergence theorems of implicit and explicit schemes. The results obtained in this paper extend and improve many recent ones announced by many others.

  19. Strict Fathers, Competing Culture(s), and Racialized Poverty: White South African Teachers' Conceptions of Themselves as Racialized Actors

    Science.gov (United States)

    Casey, Zachary A.

    2016-01-01

    This article focuses in particular on four white South African female practicing P-12 teachers' narratives about their own racialized understanding of their classroom practice(s) and their (racio-cultural) self-identity. Each of the four participants reported growing up with what they described as "strict fathers" and shared ways in…

  20. Maintaining Aura's Orbit Requirements While Performing Orbit Maintenance Maneuvers Containing an Orbit Normal Delta-V Component

    Science.gov (United States)

    Johnson, Megan R.; Petersen, Jeremy D.

    2014-01-01

    The Earth Observing System (EOS) Afternoon Constellation consists of five member missions (GCOM-W1, Aqua, CALIPSO, CloudSat, and Aura), each of which maintain a frozen, sun-synchronous orbit with a 16-day repeating ground track that follows the Worldwide Reference System-2 (WRS-2). Under nominal science operations for Aura, the propulsion system is oriented such that the resultant thrust vector is aligned 13.493 degrees away from the velocity vector along the yaw axis. When performing orbit maintenance maneuvers, the spacecraft performs a yaw slew to align the thrust vector in the appropriate direction. A new Drag Make Up (DMU) maneuver operations scheme has been implemented for Aura alleviating the need for the 13.493 degree yaw slew. The focus of this investigation is to assess the impact that no-slew DMU maneuver operations will have on Aura's Mean Local Time (MLT) which drives the required along track separation between Aura and the constellation members, as well as Aura's frozen orbit properties, eccentricity and argument of perigee. Seven maneuver strategies were analyzed to determine the best operational approach. A mirror pole strategy, with maneuvers alternating at the North and South poles, was implemented operationally to minimize impact to the MLT. Additional analysis determined that the mirror pole strategy could be further modified to include frozen orbit maneuvers and thus maintain both MLT and the frozen orbit properties under noslew operations.

  1. Performance and carcass yield of broilers fed with different digestible amino acid profiles recommended by nutrients requirements tables

    Directory of Open Access Journals (Sweden)

    Pedroso AC

    2003-01-01

    Full Text Available An experiment was conducted to evaluate the effect of different digestible amino acid profiles on the performance of broilers in two phases: from 1 to 21 days and from 22 to 42 days of age. At the end of the experiment, carcass yield and cut percentages were evaluated. Nine hundred and sixty AgRoss birds were distributed in a randomized block design with four treatments (four digestible amino acid profiles: Rostagno et al. (2000, Baker & Han (1994b, Degussa (1997 and those recommended by AgRoss (2000, with six repetitions and 40 birds per repetition (20 males and 20 females. The results showed that the four diets were able to provide the requirements of the birds, since no significant differences were seen among the treatments on the performance in the two phases and on the carcass yield and cuts at 42 days of age. Males had better yields of feet, head and neck, and lower percentage of abdominal fat (p<0.05. The best cost/benefit ratio was seen for the profile established by Rostagno et al. (2000 when diets were evaluated in an ideal protein situation.

  2. Analytical Performance Requirements for Systems for Self-Monitoring of Blood Glucose With Focus on System Accuracy: Relevant Differences Among ISO 15197:2003, ISO 15197:2013, and Current FDA Recommendations.

    Science.gov (United States)

    Freckmann, Guido; Schmid, Christina; Baumstark, Annette; Rutschmann, Malte; Haug, Cornelia; Heinemann, Lutz

    2015-07-01

    In the European Union (EU), the ISO (International Organization for Standardization) 15197 standard is applicable for the evaluation of systems for self-monitoring of blood glucose (SMBG) before the market approval. In 2013, a revised version of this standard was published. Relevant revisions in the analytical performance requirements are the inclusion of the evaluation of influence quantities, for example, hematocrit, and some changes in the testing procedures for measurement precision and system accuracy evaluation, for example, number of test strip lots. Regarding system accuracy evaluation, the most important change is the inclusion of more stringent accuracy criteria. In 2014, the Food and Drug Administration (FDA) in the United States published their own guidance document for the premarket evaluation of SMBG systems with even more stringent system accuracy criteria than stipulated by ISO 15197:2013. The establishment of strict accuracy criteria applicable for the premarket evaluation is a possible approach to further improve the measurement quality of SMBG systems. However, the system accuracy testing procedure is quite complex, and some critical aspects, for example, systematic measurement difference between the reference measurement procedure and a higher-order procedure, may potentially limit the apparent accuracy of a given system. Therefore, the implementation of a harmonized reference measurement procedure for which traceability to standards of higher order is verified through an unbroken, documented chain of calibrations is desirable. In addition, the establishment of regular and standardized post-marketing evaluations of distributed test strip lots should be considered as an approach toward an improved measurement quality of available SMBG systems. © 2015 Diabetes Technology Society.

  3. End-to-end performance of cooperative relaying in spectrum-sharing systems with quality of service requirements

    KAUST Repository

    Asghari, Vahid Reza

    2011-07-01

    We propose adopting a cooperative relaying technique in spectrum-sharing cognitive radio (CR) systems to more effectively and efficiently utilize available transmission resources, such as power, rate, and bandwidth, while adhering to the quality of service (QoS) requirements of the licensed (primary) users of the shared spectrum band. In particular, we first consider that the cognitive (secondary) user\\'s communication is assisted by an intermediate relay that implements the decode-and-forward (DF) technique onto the secondary user\\'s relayed signal to help with communication between the corresponding source and the destination nodes. In this context, we obtain first-order statistics pertaining to the first- and second-hop transmission channels, and then, we investigate the end-to-end performance of the proposed spectrum-sharing cooperative relaying system under resource constraints defined to assure that the primary QoS is unaffected. Specifically, we investigate the overall average bit error rate (BER), ergodic capacity, and outage probability of the secondary\\'s communication subject to appropriate constraints on the interference power at the primary receivers. We then consider a general scenario where a cluster of relays is available between the secondary source and destination nodes. In this case, making use of the partial relay selection method, we generalize our results for the single-relay scheme and obtain the end-to-end performance of the cooperative spectrum-sharing system with a cluster of L available relays. Finally, we examine our theoretical results through simulations and comparisons, illustrating the overall performance of the proposed spectrum-sharing cooperative system and quantify its advantages for different operating scenarios and conditions. © 2011 IEEE.

  4. Identité stricte ou partielle et identification dans les phrases à copule. Comment les identifier ?

    Directory of Open Access Journals (Sweden)

    Amary-Coudreau Valérie

    2014-07-01

    éristiques propres à l’identité, ainsi que celles propres à la spécification et à l’identification, pour lesquelles X et Y ont des degrés de référentialité et/ou de prédicativité différents. Enfin, cette hypothèse nous amène à distinguer l’identité de l’identification, sur la base de tests qui, à l’inverse de Larreya (2003, différencient l’identité stricte de l’identité partielle.

  5. The Strictly Conserved Arg-321 Residue in the Active Site of Escherichia coli Topoisomerase I Plays a Critical Role in DNA Rejoining*

    Science.gov (United States)

    Narula, Gagandeep; Annamalai, Thirunavukkarasu; Aedo, Sandra; Cheng, Bokun; Sorokin, Elena; Wong, Agnes; Tse-Dinh, Yuk-Ching

    2011-01-01

    The strictly conserved arginine residue proximal to the active site tyrosine of type IA topoisomerases is required for the relaxation of supercoiled DNA and was hypothesized to be required for positioning of the scissile phosphate for DNA cleavage to take place. Mutants of recombinant Yersinia pestis topoisomerase I with hydrophobic substitutions at this position were found in genetic screening to exhibit a dominant lethal phenotype, resulting in drastic loss in Escherichia coli viability when overexpressed. In depth biochemical analysis of E. coli topoisomerase I with the corresponding Arg-321 mutation showed that DNA cleavage can still take place in the absence of this arginine function if Mg2+ is present to enhance the interaction of the enzyme with the scissile phosphate. However, DNA rejoining is inhibited in the absence of this conserved arginine, resulting in accumulation of the cleaved covalent intermediate and loss of relaxation activity. These new experimental results demonstrate that catalysis of DNA rejoining by type IA topoisomerases has a more stringent requirement than DNA cleavage. In addition to the divalent metal ions, the side chain of this arginine residue is required for the precise positioning of the phosphotyrosine linkage for nucleophilic attack by the 3′-OH end to result in DNA rejoining. Small molecules that can interfere or distort the enzyme-DNA interactions required for DNA rejoining by bacterial type IA topoisomerases could be developed into novel antibacterial drugs. PMID:21478161

  6. A Methodology to Assess the Capability of Engine Designs to Meet Closed-Loop Performance and Operability Requirements

    Science.gov (United States)

    Zinnecker, Alicia M.; Csank, Jeffrey

    2015-01-01

    Designing a closed-loop controller for an engine requires balancing trade-offs between performance and operability of the system. One such trade-off is the relationship between the 95 percent response time and minimum high-pressure compressor (HPC) surge margin (SM) attained during acceleration from idle to takeoff power. Assuming a controller has been designed to meet some specification on response time and minimum HPC SM for a mid-life (nominal) engine, there is no guarantee that these limits will not be violated as the engine ages, particularly as it reaches the end of its life. A characterization for the uncertainty in this closed-loop system due to aging is proposed that defines elliptical boundaries to estimate worst-case performance levels for a given control design point. The results of this characterization can be used to identify limiting design points that bound the possible controller designs yielding transient results that do not exceed specified limits in response time or minimum HPC SM. This characterization involves performing Monte Carlo simulation of the closed-loop system with controller constructed for a set of trial design points and developing curve fits to describe the size and orientation of each ellipse; a binary search procedure is then employed that uses these fits to identify the limiting design point. The method is demonstrated through application to a generic turbofan engine model in closed-loop with a simplified controller; it is found that the limit for which each controller was designed was exceeded by less than 4.76 percent. Extension of the characterization to another trade-off, that between the maximum high-pressure turbine (HPT) entrance temperature and minimum HPC SM, showed even better results: the maximum HPT temperature was estimated within 0.76 percent. Because of the accuracy in this estimation, this suggests another limit that may be taken into consideration during design and analysis. It also demonstrates the extension

  7. Examining the Operational Effectiveness and Accountability of Federal Agencies as Indicated in the Performance and Accountability Reports Required by the Government Performance and Results Act of 1993

    National Research Council Canada - National Science Library

    Caron, Lenn E; Farricker, Daniel A; Underwood, Jeffrey R

    2007-01-01

    .... The agencies chosen were performing at different levels of effectiveness, according to the performance and accountability scorecard produced by the Mercatus Center at George Mason University, a non...

  8. STATUS KESEHATAN GIGI, PERFORMED TREATMENT INDEX DAN REQUIRED TREATMENT INDEX ANAK SEKOLAH DASAR DI KABUPATEN CIANJUR, KARAWANG DAN SERANG

    Directory of Open Access Journals (Sweden)

    Magdarina D. Agtini

    2012-10-01

    Full Text Available Community dental health status for permanent teeth in determined by the DMF-T (Decayed Misssing and Filled Teeth. The DMF-T in a number of industrialized nations shows a tendency to drop while the trend in developing nations is increasing. In Indonesia dental caries is still the foremost problem in oral and dental diseases, Prevalence of dental caries is around 85%-99%. The DMF-T is varied, reflect geographic and ages variations. In three decade's the intensity of dental caries is increasing with each decade, 0,70 DMF-T in 1970 to be 2,30 DMF-T in 1980 and 2,70 DMF-Tin 1990. Goal of dental caries control for 2010 is DMF-T ≤ 1 for 12 years age group. Baseline study is therefore necessary to ascertain DMF-T, PTI (Performed Treatment Index and RTI (Required Treatment Index. The study was implemented in the districts of Cianjur, Karawang and Serang in West Java for two years. The study design was cohort. The respondents  were 1200 pupils aged 8 years, randomly selected with a signifzcantcy grade of p < 0,05 and power of 0,20. The study results showed average of DMF-T at the beginning was 1,52 ± 1,21, and after two years the DMF-T was 2.45 ± 1.51 comprise only of the decayed component, and There was significant different (p=0,000. The DMF-T was low WHO criteria, nevertheless the PTI (1,2% was very low and the RTI (98% was very high. The DMF_T average shows a tendency to increase, with D as the largest component and F (Filling the smallest one. The control of dental caries faces several problems, like the limited number of manpower and facilities, and limited supply of water and electricity incertain areas. Therefore treatment of dental caries with GIC fillings using the ART method should be taken into consideration receive the necessary attention.   Key words:  Status kesehatan gigi, Karies, Performed treatment Index (PTI,  Required Treatment  Index (RTI

  9. Functional Mitochondrial Complex I Is Required by Tobacco Leaves for Optimal Photosynthetic Performance in Photorespiratory Conditions and during Transients1

    Science.gov (United States)

    Dutilleul, Christelle; Driscoll, Simon; Cornic, Gabriel; De Paepe, Rosine; Foyer, Christine H.; Noctor, Graham

    2003-01-01

    The importance of the mitochondrial electron transport chain in photosynthesis was studied using the tobacco (Nicotiana sylvestris) mutant CMSII, which lacks functional complex I. Rubisco activities and oxygen evolution at saturating CO2 showed that photosynthetic capacity in the mutant was at least as high as in wild-type (WT) leaves. Despite this, steady-state photosynthesis in the mutant was reduced by 20% to 30% at atmospheric CO2 levels. The inhibition of photosynthesis was alleviated by high CO2 or low O2. The mutant showed a prolonged induction of photosynthesis, which was exacerbated in conditions favoring photorespiration and which was accompanied by increased extractable NADP-malate dehydrogenase activity. Feeding experiments with leaf discs demonstrated that CMSII had a lower capacity than the WT for glycine (Gly) oxidation in the dark. Analysis of the postillumination burst in CO2 evolution showed that this was not because of insufficient Gly decarboxylase capacity. Despite the lower rate of Gly metabolism in CMSII leaves in the dark, the Gly to Ser ratio in the light displayed a similar dependence on photosynthesis to the WT. It is concluded that: (a) Mitochondrial complex I is required for optimal photosynthetic performance, despite the operation of alternative dehydrogenases in CMSII; and (b) complex I is necessary to avoid redox disruption of photosynthesis in conditions where leaf mitochondria must oxidize both respiratory and photorespiratory substrates simultaneously. PMID:12529534

  10. What are the required maintenance and consolidation activities to run at design performance levels (injectors and LHC) until 2035?

    CERN Document Server

    Baird, S

    2014-01-01

    Assuming that Linac4 is connected to the PSB in LS2, we will outline the maintenance and basic consolidation works that will be needed to maintain design performance of the LHC and its Injector chain until 2035, with an overall reliability as good as that achieved in the first LHC operation period 2009 to 2013. Using these data we will estimate the shutdown schedule needed throughout this period to complete these maintenance and consolidation works. These estimates will also include the required radiation cool-down periods, time for system re-commissioning and testing as well as the time needed to restart the accelerator chain for LHC colliding beam operation. As some of the consolidation activities needed for the PS and SPS machines are related to the radia tion dose taken by the machine equipment (e.g., irradiated cable replacement and magnet renovation) the variation of these time estimates as a function of beam losses in the Injector chain will also be covered.

  11. Airborne Laser Remote Sensor for Oil Detection and Classification : Engineering Requirements and Technical Considerations Relevant to a Performance Specification

    Science.gov (United States)

    1975-08-01

    This report outlines the engineering requirements for an Airborne Laser Remote Sensor for Oil Detection and Classification System. Detailed engineering requirements are given for the major units of the system. Technical considerations pertinent to a ...

  12. Strict liability as a legal mechanism protecting the aggrieved parties' interests within the nuclear liability regime

    International Nuclear Information System (INIS)

    Novotna, Marianna

    2016-01-01

    The no-fault liability principle of nuclear liability regime, its compensation schemes, sociological and legal grounds of its construction as well as liberation grounds are analysed. The simple existence of causation of damage and nuclear accident without necessity of proving negligence or any other type of fault on the part of the operator as an adequate basis for the operator’s strict liability is highlighted thus simplifying the litigation process eliminating potential obstacles, especially such as might exist with the burden of proof. The question of weighing the interests of society in the development of nuclear industry, the necessary extent of protection of victims of nuclear accidents and the interests of operators of nuclear facilities as main determinants of the strict nature of nuclear liability is also described. (orig.)

  13. The impact of Sleep Time-Related Information and Communication Technology (STRICT) on sleep patterns and daytime functioning in American adolescents.

    Science.gov (United States)

    Polos, Peter G; Bhat, Sushanth; Gupta, Divya; O'Malley, Richard J; DeBari, Vincent A; Upadhyay, Hinesh; Chaudhry, Saqib; Nimma, Anitha; Pinto-Zipp, Genevieve; Chokroverty, Sudhansu

    2015-10-01

    This cross-sectional study explored the extent and impact of mobile device-based Sleep Time-Related Information and Communication Technology (STRICT) use among American adolescents (N = 3139, 49.3% female, mean age = 13.3 years). Nearly 62% used STRICT after bedtime, 56.7% texted/tweeted/messaged in bed, and 20.8% awoke to texts. STRICT use was associated with insomnia, daytime sleepiness, eveningness, academic underperformance, later bedtimes and shorter sleep duration. Moderation analysis demonstrated that the association between STRICT use and insomnia increased with age, the association between STRICT use and daytime sleepiness decreased with age, and the association between STRICT use and shorter sleep duration decreased with age and was stronger in girls. Insomnia and daytime sleepiness partially mediated the relationship between STRICT use and academic underperformance. Our results illustrate the adverse interactions between adolescent STRICT use and sleep, with deleterious effects on daytime functioning. These worrisome findings suggest that placing reasonable limitations on adolescent STRICT use may be appropriate. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  14. Strict versus liberal target range for perioperative glucose in patients undergoing coronary artery bypass grafting: a prospective randomized controlled trial.

    Science.gov (United States)

    Desai, Shalin P; Henry, Linda L; Holmes, Sari D; Hunt, Sharon L; Martin, Chidima T; Hebsur, Shrinivas; Ad, Niv

    2012-02-01

    The purpose of this study was to test the hypothesis that a liberal blood glucose strategy (121-180 mg/dL) is not inferior to a strict blood glucose strategy (90-120 mg/dL) for outcomes in patients after first-time isolated coronary artery bypass grafting and is superior for glucose control and target blood glucose management. A total of 189 patients undergoing coronary artery bypass grafting were investigated in this prospective randomized study to compare 2 glucose control strategies on patient perioperative outcomes. Three methods of analyses (intention to treat, completer, and per protocol) were conducted. Observed power was robust (>80%) for significant results. The groups were similar on preoperative hemoglobin A(1c) and number of diabetic patients. The liberal group was found to be noninferior to the strict group for perioperative complications and superior on glucose control and target range management. The liberal group had significantly fewer patients with hypoglycemic events (liberal range after coronary artery bypass grafting led to similar outcomes compared with a strict target range and was superior in glucose control and target range management. On the basis of the results of this study, a target blood glucose range of 121 to 180 mg/dL is recommended for patients after coronary artery bypass grafting as advocated by the Society of Thoracic Surgeons. Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

  15. Examining the Operational Effectiveness and Accountability of Federal Agencies as Indicated in the Performance and Accountability Reports Required by the Government Performance and Results Act of 1993

    National Research Council Canada - National Science Library

    Caron, Lenn E; Farricker, Daniel A; Underwood, Jeffrey R

    2007-01-01

    The Government Performance and Results Act of 1993 (GPRA) was enacted to improve the confidence of the American people in the capability of the federal government and to initiate program performance improvement...

  16. Towards the strict legal enforcement of best practice principles in oil ...

    African Journals Online (AJOL)

    The article found that environmental regulations are often ineffective because they are substantively inadequate and/or inadequately enforced. This accounts for environmental pollution arising from oil and gas industry. The article highlighted some of the best approaches to achieving high environmental performance in the ...

  17. The Strict Liability Principle and the Human Rights of the Athlete in Doping Cases

    NARCIS (Netherlands)

    J.W. Soek

    2006-01-01

    textabstractAthletes who achieve extraordinary feats on the pitch stir up the imagination and enjoy a unique position within society. However, laurels received one day, may be just as quickly snatched back the next if it becomes known that the athlete achieved his or her exceptional performance

  18. The effect of joystick handle size and gain at two levels of required precision on performance and physical load on crane operators

    NARCIS (Netherlands)

    Huysmans, M.A.; Looze, M.P. de; Hoozemans, M.J.M.; Beek, A.J. van der; Dieën, J.H. van

    2006-01-01

    The study was designed to determine the effect of joystick handle size and (display-control) gain at two levels of required task precision on performance and physical load on crane operators. Eight experienced crane operators performed a simulated crane operation task on a computer by use of a

  19. 40 CFR Table 32 to Subpart Uuu of... - Requirements for Performance Tests for HAP Emissions From Sulfur Recovery Units Not Subject to...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 12 2010-07-01 2010-07-01 true Requirements for Performance Tests for HAP Emissions From Sulfur Recovery Units Not Subject to the New Source Performance Standards for...: Catalytic Cracking Units, Catalytic Reforming Units, and Sulfur Recovery Units Pt. 63, Subpt. UUU, Table 32...

  20. Evaluation of a strict protocol approach in managing women with severe disease due to hypertension in pregnancy: A before and after study

    Directory of Open Access Journals (Sweden)

    Backer Fèbè

    2005-09-01

    Full Text Available Abstract Background To evaluate whether the introduction of a strict protocol based on the systemic evaluation of critically ill pregnant women with complications of hypertension affected the outcome of those women. Method Study group: Indigent South African women managed in the tertiary hospitals of the Pretoria Academic Complex. Since 1997 a standard definition of women with severe acute maternal morbidity (SAMM, also referred to as a Nearmiss, has been used in the Pretoria Academic Complex. All cases of SAMM and maternal deaths (MD were entered on the Maternal Morbidity and Mortality Audit System programme (MaMMAS. A comparison of outcome of severely ill women who had complications of hypertension in pregnancy was performed between 1997–1998 (original protocol and 2002–2003 (strict protocol. Data include women referred from outside the Pretoria Academic Complex area to the tertiary hospitals. Results Between 1997–1998 there were 79 women with SAMM and 18 maternal deaths due to complications of hypertension, compared with 91 women with SAMM and 13 maternal deaths in 2002–2003. The mortality index (MI declined from 18.6% to 12.5% (OR 0.62, 95% CI 0.27–1.45. Statistically significant fewer women had renal failure (RR 0.37, 95% CI 0.21 – 0.66 and cerebral complications (RR 0.52, 95%CI 0.34 – 0.81 during the second period, and liver dysfunction (RR 0.27 95%CI 0.06 – 1.25 tended to be lower. However, there tended to be an increase in the number of women, who had immune system failure (RR 4.2 95%CI 0.93 – 18.94 and respiratory failure (RR 1.42 95%CI 0.88 – 2.29 although it did not reach significance. Cardiac failure remained constant (RR 0.84 95%CI 0.54 – 1.30. Conclusion The strict protocol approach based on the systemic evaluation of severely ill pregnant women with complications of hypertension and an intensive, regular feedback mechanism has been associated with a reduction in the number of patients with renal failure and

  1. On combination of strict Bayesian principles with model reduction technique or how stochastic model calibration can become feasible for large-scale applications

    Science.gov (United States)

    Oladyshkin, S.; Schroeder, P.; Class, H.; Nowak, W.

    2013-12-01

    Predicting underground carbon dioxide (CO2) storage represents a challenging problem in a complex dynamic system. Due to lacking information about reservoir parameters, quantification of uncertainties may become the dominant question in risk assessment. Calibration on past observed data from pilot-scale test injection can improve the predictive power of the involved geological, flow, and transport models. The current work performs history matching to pressure time series from a pilot storage site operated in Europe, maintained during an injection period. Simulation of compressible two-phase flow and transport (CO2/brine) in the considered site is computationally very demanding, requiring about 12 days of CPU time for an individual model run. For that reason, brute-force approaches for calibration are not feasible. In the current work, we explore an advanced framework for history matching based on the arbitrary polynomial chaos expansion (aPC) and strict Bayesian principles. The aPC [1] offers a drastic but accurate stochastic model reduction. Unlike many previous chaos expansions, it can handle arbitrary probability distribution shapes of uncertain parameters, and can therefore handle directly the statistical information appearing during the matching procedure. We capture the dependence of model output on these multipliers with the expansion-based reduced model. In our study we keep the spatial heterogeneity suggested by geophysical methods, but consider uncertainty in the magnitude of permeability trough zone-wise permeability multipliers. Next combined the aPC with Bootstrap filtering (a brute-force but fully accurate Bayesian updating mechanism) in order to perform the matching. In comparison to (Ensemble) Kalman Filters, our method accounts for higher-order statistical moments and for the non-linearity of both the forward model and the inversion, and thus allows a rigorous quantification of calibrated model uncertainty. The usually high computational costs of

  2. The Test of Logical Thinking as a predictor of first-year pharmacy students' performance in required first-year courses.

    Science.gov (United States)

    Etzler, Frank M; Madden, Michael

    2014-08-15

    To investigate the correlation of scores on the Test of Logical Thinking (TOLT) with first-year pharmacy students' performance in selected courses. The TOLT was administered to 130 first-year pharmacy students. The examination was administered during the first quarter in a single session. The TOLT scores correlated with grades earned in Pharmaceutical Calculations, Physical Pharmacy, and Basic Pharmacokinetics courses. Performance on the TOLT has been correlated to performance in courses that required the ability to use quantitative reasoning to complete required tasks. In the future, it may be possible to recommend remediation, retention, and/or admission based in part on the results from the TOLT.

  3. An Ultra-light PRNG Passing Strict Randomness Tests and Suitable for Low Cost Tags

    Directory of Open Access Journals (Sweden)

    OZCANHAN, M. H.

    2016-08-01

    Full Text Available A pseudo-random number generator for low-cost RFID tags is presented. The scheme is simple, sequential and secure, yet has a high performance. Despite its lowest hardware complexity, our proposal represents a better alternative than previous proposals for low-cost tags. The scheme is based on the well-founded pseudo random number generator, Mersenne Twister. The proposed generator takes low-entropy seeds extracted from a physical characteristic of the tag and produces outputs that pass popular randomness tests. Contrarily, previous proposal tests are based on random number inputs from a popular online source, which are simply unavailable to tags. The high performance and satisfactory randomness of present work are supported by extensive test results and compared with similar previous works. Comparison using proven estimation formulae indicates that our proposal has the best hardware complexity, power consumption, and the least cost.

  4. 75 FR 30159 - Automatic Dependent Surveillance-Broadcast (ADS-B) Out Performance Requirements To Support Air...

    Science.gov (United States)

    2010-05-28

    ... Organisation for Civil Aviation Equipment EUROCONTROL--European Organisation for the Safety of Air Navigation... transmit the large message structures required by FIS-B. The UAT broadcast link supports ADS-B In...

  5. Effectiveness of strict vs. multiple use protected areas in reducing tropical forest fires: a global analysis using matching methods.

    Directory of Open Access Journals (Sweden)

    Andrew Nelson

    Full Text Available Protected areas (PAs cover a quarter of the tropical forest estate. Yet there is debate over the effectiveness of PAs in reducing deforestation, especially when local people have rights to use the forest. A key analytic problem is the likely placement of PAs on marginal lands with low pressure for deforestation, biasing comparisons between protected and unprotected areas. Using matching techniques to control for this bias, this paper analyzes the global tropical forest biome using forest fires as a high resolution proxy for deforestation; disaggregates impacts by remoteness, a proxy for deforestation pressure; and compares strictly protected vs. multiple use PAs vs indigenous areas. Fire activity was overlaid on a 1 km map of tropical forest extent in 2000; land use change was inferred for any point experiencing one or more fires. Sampled points in pre-2000 PAs were matched with randomly selected never-protected points in the same country. Matching criteria included distance to road network, distance to major cities, elevation and slope, and rainfall. In Latin America and Asia, strict PAs substantially reduced fire incidence, but multi-use PAs were even more effective. In Latin America, where there is data on indigenous areas, these areas reduce forest fire incidence by 16 percentage points, over two and a half times as much as naïve (unmatched comparison with unprotected areas would suggest. In Africa, more recently established strict PAs appear to be effective, but multi-use tropical forest protected areas yield few sample points, and their impacts are not robustly estimated. These results suggest that forest protection can contribute both to biodiversity conservation and CO2 mitigation goals, with particular relevance to the REDD agenda. Encouragingly, indigenous areas and multi-use protected areas can help to accomplish these goals, suggesting some compatibility between global environmental goals and support for local livelihoods.

  6. Hydroxycinnamic acids used as external acceptors of electrons: an energetic advantage for strictly heterofermentative lactic acid bacteria.

    Science.gov (United States)

    Filannino, Pasquale; Gobbetti, Marco; De Angelis, Maria; Di Cagno, Raffaella

    2014-12-01

    The metabolism of hydroxycinnamic acids by strictly heterofermentative lactic acid bacteria (19 strains) was investigated as a potential alternative energy route. Lactobacillus curvatus PE5 was the most tolerant to hydroxycinnamic acids, followed by strains of Weissella spp., Lactobacillus brevis, Lactobacillus fermentum, and Leuconostoc mesenteroides, for which the MIC values were the same. The highest sensitivity was found for Lactobacillus rossiae strains. During growth in MRS broth, lactic acid bacteria reduced caffeic, p-coumaric, and ferulic acids into dihydrocaffeic, phloretic, and dihydroferulic acids, respectively, or decarboxylated hydroxycinnamic acids into the corresponding vinyl derivatives and then reduced the latter compounds to ethyl compounds. Reductase activities mainly emerged, and the activities of selected strains were further investigated in chemically defined basal medium (CDM) under anaerobic conditions. The end products of carbon metabolism were quantified, as were the levels of intracellular ATP and the NAD(+)/NADH ratio. Electron and carbon balances and theoretical ATP/glucose yields were also estimated. When CDM was supplemented with hydroxycinnamic acids, the synthesis of ethanol decreased and the concentration of acetic acid increased. The levels of these metabolites reflected on the alcohol dehydrogenase and acetate kinase activities. Overall, some biochemical traits distinguished the common metabolism of strictly heterofermentative strains: main reductase activity toward hydroxycinnamic acids, a shift from alcohol dehydrogenase to acetate kinase activities, an increase in the NAD(+)/NADH ratio, and the accumulation of supplementary intracellular ATP. Taken together, the above-described metabolic responses suggest that strictly heterofermentative lactic acid bacteria mainly use hydroxycinnamic acids as external acceptors of electrons. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  7. Scurvy in the present times: vitamin C allergy leading to strict fast food diet.

    Science.gov (United States)

    Shaath, Tarek; Fischer, Ryan; Goeser, Megan; Rajpara, Anand; Aires, Daniel

    2016-01-15

    Scurvy results from a deficiency of vitamin C, a nutrient otherwise known as ascorbic acid. Today, scurvy is rare yet emerges in select patients. The patient reported herein developed scurvy secondary to deliberate avoidance of vitamin C-rich foods. Classic cutaneous manifestations of scurvy include follicular hyperkeratosis and perifollicular hemorrhage encompassing coiled "corkscrew" hairs and hairs bent into "swan-neck" deformities. Ecchymoses, purpura, and petechiae are also characteristically prominent. Classic oral abnormalities include erythematous, swollen gingivae that hemorrhage from subtle microtrauma.Subungual linear splinter hemorrhages may also manifest as a sign of the disease. To establish the diagnosis requirements include characteristic physical exam findings, evidence of inadequate dietary intake, and rapid reversal of symptoms upon supplementation. Although unnecessary for diagnosis, histological findings demonstrate perifollicular inflammation and hemorrhage, fibrosis, and hyperkeratosis, amongst dilated hair follicles and keratin plugging. Although citrus fruit allergies have been historically documented, ascorbic acid has not been previously reported as an allergen. Although lacking absolute certainty, this report suggests a presumed case of ascorbic acid allergy based on patient history and favorable response to ascorbic acid desensitization therapy.

  8. Composite Intelligent Learning Control of Strict-Feedback Systems With Disturbance.

    Science.gov (United States)

    Xu, Bin; Sun, Fuchun

    2018-02-01

    This paper addresses the dynamic surface control of uncertain nonlinear systems on the basis of composite intelligent learning and disturbance observer in presence of unknown system nonlinearity and time-varying disturbance. The serial-parallel estimation model with intelligent approximation and disturbance estimation is built to obtain the prediction error and in this way the composite law for weights updating is constructed. The nonlinear disturbance observer is developed using intelligent approximation information while the disturbance estimation is guaranteed to converge to a bounded compact set. The highlight is that different from previous work directly toward asymptotic stability, the transparency of the intelligent approximation and disturbance estimation is included in the control scheme. The uniformly ultimate boundedness stability is analyzed via Lyapunov method. Through simulation verification, the composite intelligent learning with disturbance observer can efficiently estimate the effect caused by system nonlinearity and disturbance while the proposed approach obtains better performance with higher accuracy.

  9. Fermentative Degradation of Polyethylene Glycol by a Strictly Anaerobic, Gram-Negative, Nonsporeforming Bacterium, Pelobacter venetianus sp. nov

    OpenAIRE

    1983-01-01

    The synthetic polyether polyethylene glycol (PEG) with a molecular weight of 20,000 was anaerobically degraded in enrichment cultures inoculated with mud of limnic and marine origins. Three strains (Gra PEG 1, Gra PEG 2, and Ko PEG 2) of rod-shaped, gram-negative, nonsporeforming, strictly anaerobic bacteria were isolated in mineral medium with PEG as the sole source of carbon and energy. All strains degraded dimers, oligomers, and polymers of PEG up to a molecular weight of 20,000 completely...

  10. An Iterative Algorithm Combining Viscosity Method with Parallel Method for a Generalized Equilibrium Problem and Strict Pseudocontractions

    Directory of Open Access Journals (Sweden)

    2009-03-01

    Full Text Available We introduce a new approximation scheme combining the viscosity method with parallel method for finding a common element of the set of solutions of a generalized equilibrium problem and the set of fixed points of a family of finitely strict pseudocontractions. We obtain a strong convergence theorem for the sequences generated by these processes in Hilbert spaces. Based on this result, we also get some new and interesting results. The results in this paper extend and improve some well-known results in the literature.

  11. Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling.

    Science.gov (United States)

    Ermilov, Alexandre N; Kumari, Archana; Li, Libo; Joiner, Ariell M; Grachtchouk, Marina A; Allen, Benjamin L; Dlugosz, Andrzej A; Mistretta, Charlotte M

    2016-11-01

    For homeostasis, lingual taste papilla organs require regulation of epithelial cell survival and renewal, with sustained innervation and stromal interactions. To investigate a role for Hedgehog/GLI signaling in adult taste organs we used a panel of conditional mouse models to manipulate GLI activity within epithelial cells of the fungiform and circumvallate papillae. Hedgehog signaling suppression rapidly led to taste bud loss, papilla disruption, and decreased proliferation in domains of papilla epithelium that contribute to taste cells. Hedgehog responding cells were eliminated from the epithelium but retained in the papilla stromal core. Despite papilla disruption and loss of taste buds that are a major source of Hedgehog ligand, innervation to taste papillae was maintained, and not misdirected, even after prolonged GLI blockade. Further, vimentin-positive fibroblasts remained in the papilla core. However, retained innervation and stromal cells were not sufficient to maintain taste bud cells in the context of compromised epithelial Hedgehog signaling. Importantly taste organ disruption after GLI blockade was reversible in papillae that retained some taste bud cell remnants where reactivation of Hedgehog signaling led to regeneration of papilla epithelium and taste buds. Therefore, taste bud progenitors were either retained during epithelial GLI blockade or readily repopulated during recovery, and were poised to regenerate taste buds once Hedgehog signaling was restored, with innervation and papilla connective tissue elements in place. Our data argue that Hedgehog signaling is essential for adult tongue tissue maintenance and that taste papilla epithelial cells represent the key targets for physiologic Hedgehog-dependent regulation of taste organ homeostasis. Because disruption of GLI transcriptional activity in taste papilla epithelium is sufficient to drive taste organ loss, similar to pharmacologic Hedgehog pathway inhibition, the findings suggest that taste

  12. In vitro effect of intracanal medicaments on strict anaerobes by means of the broth dilution method

    Directory of Open Access Journals (Sweden)

    ROSA Odila Pereira da Silva

    2002-01-01

    Full Text Available The determination of bacterial susceptibility to intracanal medicaments is a necessity. Nevertheless, few studies utilize the proper methodology to carry out that evaluation with anaerobes. In this study, the steps of a broth dilution method, carried out in microplates (microdilution and tubes (macrodilution, to test the effect of traditional intracanal medicaments on anaerobic bacteria are described. The results are presented as values of minimal inhibitory and bactericidal concentrations (MIC and MBC. Standardized inocula of the anaerobic bacteria Prevotella nigrescens (ATCC 33563, Fusobacterium nucleatum (ATCC 25586 and Clostridium perfringens (ATCC 13124, in reinforced Clostridium medium (RCM and supplemented Brucella broth, were submitted to different concentrations of calcium hydroxide, chlorhexidine digluconate, camphorated paramonochlorophenol and formocresol solutions. The drugs were diluted in the same culture broths, in microplates and tubes, and were then incubated in anaerobiosis jars at 37ºC for 48 or 96 hours. The determination of MICs was carried out through visual and spectrophotometric readings, and the determination of MBCs, through the plating of aliquots on RCM-blood agar. For that kind of study, the macromethod with spectrophotometric reading should be the natural choice. MICs and MBCs obtained with the macromethod were compatible with the known clinical performance of the studied medications, and the values varied according to the bacteria and culture media employed. RCM was the most effective medium and C. perfringens, the most resistant microorganism.

  13. Strictly monolayer large continuous MoS{sub 2} films on diverse substrates and their luminescence properties

    Energy Technology Data Exchange (ETDEWEB)

    Mohapatra, P. K.; Deb, S.; Singh, B. P.; Vasa, P.; Dhar, S., E-mail: dhar@phy.iitb.ac.in [Department of Physics, Indian Institute of Technology Bombay, Mumbai 400076 (India)

    2016-01-25

    Despite a tremendous interest on molybdenum disulfide as a thinnest direct band gap semiconductor, single step synthesis of a large area purely monolayer MoS{sub 2} film has not yet been reported. Here, we report a CVD route to synthesize a continuous film of strictly monolayer MoS{sub 2} covering an area as large as a few cm{sup 2} on a variety of different substrates without using any seeding material or any elaborate pretreatment of the substrate. This is achieved by allowing the growth to take place in the naturally formed gap between a piece of SiO{sub 2} coated Si wafer and the substrate, when the latter is placed on top of the former inside a CVD reactor. We propose a qualitative model to explain why the MoS{sub 2} films are always strictly monolayer in this method. The photoluminescence study of these monolayers shows the characteristic excitonic and trionic features associated with monolayer MoS{sub 2}. In addition, a broad defect related luminescence band appears at ∼1.7 eV. As temperature decreases, the intensity of this broad feature increases, while the band edge luminescence reduces.

  14. Event-Sampled Direct Adaptive NN Output- and State-Feedback Control of Uncertain Strict-Feedback System.

    Science.gov (United States)

    Szanto, Nathan; Narayanan, Vignesh; Jagannathan, Sarangapani

    2017-04-12

    In this paper, a novel event-triggered implementation of a tracking controller for an uncertain strict-feedback system is presented. Neural networks (NNs) are utilized in the backstepping approach to design a control input by approximating unknown dynamics of the strict-feedback nonlinear system with event-sampled inputs. The system state vector is assumed to be unknown and an NN observer is used to estimate the state vector. By using the estimated state vector and backstepping design approach, an event-sampled controller is introduced. As part of the controller design, first, input-to-state-like stability for a continuously sampled controller that has been injected with bounded measurement errors is demonstrated, and subsequently, an event-execution control law is derived, such that the measurement errors are guaranteed to remain bounded. Lyapunov theory is used to demonstrate that the tracking errors, the observer estimation errors, and the NN weight estimation errors for each NN are locally uniformly ultimately bounded in the presence bounded disturbances, NN reconstruction errors, as well as errors introduced by event sampling. Simulation results are provided to illustrate the effectiveness of the proposed controllers.

  15. NWTS program criteria for mined geologic disposal of nuclear waste: program objectives, functional requirements, and system performance criteria

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-04-01

    At the present time, final repository criteria have not been issued by the responsible agencies. This document describes general objectives, requirements, and criteria that the DOE intends to apply in the interim to the National Waste Terminal Storage (NWTS) Program. These objectives, requirements, and criteria have been developed on the basis of DOE's analysis of what is needed to achieve the National objective of safe waste disposal in an environmentally acceptable and economic manner and are expected to be consistent with anticipated regulatory standards. The qualitative statements in this document address the broad issues of public and occupational health and safety, institutional acceptability, engineering feasibility, and economic considerations. A comprehensive set of criteria, general and project specific, of which these are a part, will constitute a portion of the technical basis for preparation and submittal by the DOE of formal documents to support future license applications for nuclear waste repositories.

  16. NWTS program criteria for mined geologic disposal of nuclear waste: program objectives, functional requirements, and system performance criteria

    International Nuclear Information System (INIS)

    1981-04-01

    At the present time, final repository criteria have not been issued by the responsible agencies. This document describes general objectives, requirements, and criteria that the DOE intends to apply in the interim to the National Waste Terminal Storage (NWTS) Program. These objectives, requirements, and criteria have been developed on the basis of DOE's analysis of what is needed to achieve the National objective of safe waste disposal in an environmentally acceptable and economic manner and are expected to be consistent with anticipated regulatory standards. The qualitative statements in this document address the broad issues of public and occupational health and safety, institutional acceptability, engineering feasibility, and economic considerations. A comprehensive set of criteria, general and project specific, of which these are a part, will constitute a portion of the technical basis for preparation and submittal by the DOE of formal documents to support future license applications for nuclear waste repositories

  17. The FAIR timing master: a discussion of performance requirements and architectures for a high-precision timing system

    International Nuclear Information System (INIS)

    Kreider, M.

    2012-01-01

    Production chains in a particle accelerator are complex structures with many inter-dependencies and multiple paths to consider. This ranges from system initialization and synchronization of numerous machines to interlock handling and appropriate contingency measures like beam dump scenarios. The FAIR facility will employ White-Rabbit, a time based system which delivers an instruction and a corresponding execution time to a machine. In order to meet the deadlines in any given production chain, instructions need to be sent out ahead of time. For this purpose, code execution and message delivery times need to be known in advance. The FAIR Timing Master needs to be reliably capable of satisfying these timing requirements as well as being fault tolerant. Event sequences of recorded production chains indicate that low reaction times to internal and external events and fast, parallel execution are required. This suggests a slim architecture, especially devised for this purpose. Using the thread model of an OS or other high level programs on a generic CPU would be counterproductive when trying to achieve deterministic processing times. This paper deals with the analysis of said requirements as well as a comparison of known processor and virtual machine architectures and the possibilities of parallelization in programmable hardware. In addition, existing proposals at GSI will be checked against these findings. The final goal will be to determine the best instruction set for modeling any given production chain and devising a suitable architecture to execute these models. (authors)

  18. Membrane-aerated biofilms for high rate biotreatment: performance appraisal, engineering principles, scale-up, and development requirements.

    Science.gov (United States)

    Syron, Eoin; Casey, Eoin

    2008-03-15

    Diffusion of the electron acceptor is the rate controlling step in virtually all biofilm reactors employed for aerobic wastewater treatment. The membrane-aerated biofilm reactor (MABR) is a technology that can deliver oxygen at high rates and transfer efficiencies, thereby enhancing the biofilm activity. This paper provides a comparative performance rate analysis of the MABR in terms of its application for carbonaceous pollutant removal, nitrification/denitrification and xenobiotic biotreatment. We also describe the mechanisms influencing process performance in the MABR and the inter-relationships between these factors. The challenges involved in scaling-up the process are discussed with recommendations for prioritization of research needs.

  19. Performance/Design Requirements and Detailed Technical Description for a Computer-Directed Training Subsystem for Integration into the Air Force Phase II Base Level System.

    Science.gov (United States)

    Butler, A. K.; And Others

    The performance/design requirements and a detailed technical description for a Computer-Directed Training Subsystem to be integrated into the Air Force Phase II Base Level System are described. The subsystem may be used for computer-assisted lesson construction and has presentation capability for on-the-job training for data automation, staff, and…

  20. The Impact on IPO Performance of More Stringent Listing Rules with a Pre-listing Earnings Requirement: Evidence from Hong Kong

    OpenAIRE

    Wai-yan Cheng; Yan-leung Cheung; Yuen-ching Tse

    2005-01-01

    This study considers the impact of a change to listing rules covering IPO performance in the Hong Kong stock market. The change, introduced in 1994, imposed a three-year pre-listing earning requirement on new issues. The objective of this research is to screen out a subset of poor IPO performers. We find there is no significant difference in performance between IPOs before and after the regulatory change. We further divide our sample of IPOs registered before the regulatory change into two su...

  1. Next Generation Microbiology Requirements

    Science.gov (United States)

    Ott, C. M.; Oubre, C. M.; Elliott, T. F.; Castro, V. A.; Pierson, D. L.

    2012-01-01

    As humans continue to explore deep into space, microorganisms will travel with them. The primary means to mitigate the risk of infectious disease are a combination of prudent spacecraft design and rigorous operational controls. The effectiveness of these methods are evaluated by microbiological monitoring of spacecraft, food, water, and the crew that is performed preflight, in-flight, and post-flight. Current NASA requirements associated with microbiological monitoring are based on culture-based methodology where microorganisms are grown on a semi-solid growth medium and enumerated. Subsequent identification of the organisms requires specialized labor and large equipment, which historically has been performed on Earth. Requirements that rely strictly on culture-based units limit the use of non-culture based monitoring technology. Specifically, the culture-based "measurement criteria" are Colony Forming Units (CFU, representing the growth of one microorganism at a single location on the agar medium) per a given volume, area, or sample size. As the CFU unit by definition is culture-based, these requirements limit alternative technologies for spaceflight applications. As spaceflight missions such as those to Mars extend further into space, culture-based technology will become difficult to implement due to the (a) limited shelf life of the culture media, (b) mass/volume necessary to carry these consumables, and (c) problems associated with the production of biohazardous material in the habitable volume of the spacecraft. In addition, an extensive amount of new knowledge has been obtained during the Space Shuttle, NASA-Mir, and International Space Station Programs, which gave direction for new or modified microbial control requirements for vehicle design and mission operations. The goal of this task is to develop and recommend a new set of requirements for vehicle design and mission operations, including microbiological monitoring, based upon "lessons learned" and new

  2. The Test of Logical Thinking as a Predictor of First-Year Pharmacy Students’ Performance in Required First-Year Courses

    Science.gov (United States)

    Madden, Michael

    2014-01-01

    Objectives. To investigate the correlation of scores on the Test of Logical Thinking (TOLT) with first-year pharmacy students’ performance in selected courses. Methods. The TOLT was administered to 130 first-year pharmacy students. The examination was administered during the first quarter in a single session. Results. The TOLT scores correlated with grades earned in Pharmaceutical Calculations, Physical Pharmacy, and Basic Pharmacokinetics courses. Conclusion. Performance on the TOLT has been correlated to performance in courses that required the ability to use quantitative reasoning to complete required tasks. In the future, it may be possible to recommend remediation, retention, and/or admission based in part on the results from the TOLT. PMID:25147393

  3. Strict fibonacci heaps

    DEFF Research Database (Denmark)

    Brodal, Gerth Stølting; Lagogiannis, George; Tarjan, Robert E.

    2012-01-01

    We present the first pointer-based heap implementation with time bounds matching those of Fibonacci heaps in the worst case. We support make-heap, insert, find-min, meld and decrease-key in worst-case O(1) time, and delete and delete-min in worst-case O(lg n) time, where n is the size of the heap...... of the smaller heap when doing a meld. We use the pigeonhole principle in place of the redundant counter mechanism. We present the first pointer-based heap implementation with time bounds matching those of Fibonacci heaps in the worst case. We support make-heap, insert, find-min, meld and decrease-key in worst...

  4. Analysis of strictly bound modes in photonic crystal fibers by use of a source-model technique.

    Science.gov (United States)

    Hochman, Amit; Leviatan, Yehuda

    2004-06-01

    We describe a source-model technique for the analysis of the strictly bound modes propagating in photonic crystal fibers that have a finite photonic bandgap crystal cladding and are surrounded by an air jacket. In this model the field is simulated by a superposition of fields of fictitious electric and magnetic current filaments, suitably placed near the media interfaces of the fiber. A simple point-matching procedure is subsequently used to enforce the continuity conditions across the interfaces, leading to a homogeneous matrix equation. Nontrivial solutions to this equation yield the mode field patterns and propagation constants. As an example, we analyze a hollow-core photonic crystal fiber. Symmetry characteristics of the modes are discussed and exploited to reduce the computational burden.

  5. Development of a PCR assay based on the 16S-23S rDNA internal transcribed spacer for identification of strictly anaerobic bacterium Zymophilus

    Czech Academy of Sciences Publication Activity Database

    Felsberg, Jürgen; Jelínková, Markéta; Kubizniaková, P.; Matoulková, D.

    2015-01-01

    Roč. 33, June (2015), s. 85-89 ISSN 1075-9964 Institutional support: RVO:61388971 Keywords : Brewing microbiology * Strictly anaerobic bacteria * Yeast contamination Subject RIV: GM - Food Processing Impact factor: 2.424, year: 2015

  6. Strict blood glucose control by an artificial endocrine pancreas during hepatectomy may prevent postoperative acute kidney injury.

    Science.gov (United States)

    Mita, Naoji; Kawahito, Shinji; Soga, Tomohiro; Takaishi, Kazumi; Kitahata, Hiroshi; Matsuhisa, Munehide; Shimada, Mitsuo; Kinoshita, Hiroyuki; Tsutsumi, Yasuo M; Tanaka, Katsuya

    2017-03-01

    The aim of the present study was to evaluate the usefulness of a closed-loop system (STG-55; Nikkiso, Tokyo, Japan), a type of artificial endocrine pancreas for the continuous monitoring and control of intraoperative blood glucose, for preventing postoperative acute kidney injury (AKI) in patients undergoing hepatectomy. Thirty-eight patients were enrolled in this study. Glucose concentrations were controlled with either a manual injection of insulin based on a commonly used sliding scale (manual insulin group, n = 19) or the programmed infusion of insulin determined by the control algorithm of the artificial endocrine pancreas (programmed insulin group, n = 19). After the induction of anesthesia, a 20-G intravenous catheter was inserted into the peripheral forearm vein of patients in the programmed insulin group and connected to an artificial endocrine pancreas (STG-55). The target range for glucose concentrations was set to 100-150 mg/dL. The mean serum creatinine concentrations of preoperative, postoperative 24 and 48 h were 0.72, 0.78, and 0.79 mg/dL in the programmed insulin group, and 0.81, 0.95, and 1.03 mg/dL in the manual insulin group, respectively. Elevations in serum creatinine concentrations postoperative 48 h were significantly suppressed in the programmed insulin group. The STG-55 closed-loop system was effective for maintaining strict blood glucose control during hepatectomy with minimal variability in blood glucose concentrations and for suppressing elevations in serum creatinine concentrations. Strict blood glucose control by an artificial endocrine pancreas during hepatectomy may prevent postoperative AKI.

  7. The food and drug administration is now preparing to establish tighter performance requirements for blood glucose monitors.

    Science.gov (United States)

    Klonoff, David C

    2010-05-01

    On March 16 and 17, 2010, the Food and Drug Administration (FDA) presented a public meeting about blood glucose monitoring at the Gaithersberg Hilton Hotel. The meeting was intended to present expert opinions and solicit input from the public about whether to develop new regulatory policies for blood glucose monitors. The meeting was divided into three sections: (1) Clinical Accuracy Requirements for Blood Glucose Monitors, (2) Interferences and Limitations of Blood Glucose Monitors, and (3) Tight Glycemic Control. Many officials from the Center for Devices and Radiologic Health and the Office of In Vitro Diagnostic Devices, which are the parts of FDA that regulate approval of blood glucose monitors, either spoke on the agenda or attended in the audience. Approximately 300 people attended; they were mostly clinicians (such as adult endocrinologists, pediatric endocrinologists, internists, clinical chemists, intensivists, surgeons, nurses, and diabetes educators) or industry officials from companies involved in glucose monitoring, pharmaceutical products, data analysis, or regulatory consulting. (c) 2010 Diabetes Technology Society.

  8. Reliable quantification of bite-force performance requires use of appropriate biting substrate and standardization of bite out-lever.

    Science.gov (United States)

    Lappin, A Kristopher; Jones, Marc E H

    2014-12-15

    Bite-force performance is an ecologically important measure of whole-organism performance that shapes dietary breadth and feeding strategies and, in some taxa, determines reproductive success. It also is a metric that is crucial to testing and evaluating biomechanical models. We reviewed nearly 100 published studies of a range of taxa that incorporate direct in vivo measurements of bite force. Problematically, methods of data collection and processing vary considerably among studies. In particular, there is little consensus on the appropriate substrate to use on the biting surface of force transducers. In addition, the bite out-lever, defined as the distance from the fulcrum (i.e. jaw joint) to the position along the jawline at which the jaws engage the transducer, is rarely taken into account. We examined the effect of bite substrate and bite out-lever on bite-force estimates in a diverse sample of lizards. Results indicate that both variables have a significant impact on the accuracy of measurements. Maximum bite force is significantly greater using leather as the biting substrate compared with a metal substrate. Less-forceful bites on metal are likely due to inhibitory feedback from mechanoreceptors that prevent damage to the feeding apparatus. Standardization of bite out-lever affected which trial produced maximum performance for a given individual. Indeed, maximum bite force is usually underestimated without standardization because it is expected to be greatest at the minimum out-lever (i.e. back of the jaws), which in studies is rarely targeted with success. We assert that future studies should use a pliable substrate, such as leather, and use appropriate standardization for bite out-lever. © 2014. Published by The Company of Biologists Ltd.

  9. Dizzy people perform no worse at a motor imagery task requiring whole body mental rotation; a case-control comparison

    Directory of Open Access Journals (Sweden)

    Sarah B Wallwork

    2013-06-01

    Full Text Available We wanted to find out whether people who suffer from dizziness take longer than people who do not, to perform a motor imagery task that involves implicit whole body rotation. Our prediction was that people in the ‘dizzy’ group would take longer at a left/right neck rotation judgment task but not a left/right hand judgment task, because actually performing the former, but not the latter, would exacerbate their dizziness. Secondly, we predicted that when dizzy participants responded to neck rotation images, responses would be greatest when images were in the upside-down orientation; an orientation with greatest dizzy-provoking potential. To test this idea, we used a case-control comparison design. One hundred and eighteen participants who suffered from dizziness and 118 age, gender, arm pain and neck pain matched controls took part in the study. Participants undertook two motor imagery tasks; a left/right neck rotation judgment task and a left/right hand judgment task. The tasks were completed using the Recognise program; an on-line reaction time task program. Images of neck rotation were shown in four different orientations; 0°, 90°, 180° and 270°. Participants were asked to respond to each ‘neck’ image identifying it as either ‘right neck rotation’ or a ‘left neck rotation’, or for hands, a right or a left hand. Results showed that participants in the ‘dizzy’ group were slower than controls at both tasks (p= 0.015, but this was not related to task (p= 0.498. Similarly, ‘dizzy’ participants were not proportionally worse at images of different orientations (p= 0.878. Our findings suggest impaired performance in dizzy people, an impairment that may be confined to motor imagery or may extend more generally.

  10. Job Language Performance Requirements for MOS 91B, Medical Specialist, Reference Soldier’s Manual Dated 30 August 1977.

    Science.gov (United States)

    1977-08-30

    sprayed have been corrected passive+verb+ing "task will be performed using procedures" modal+passive voice "can be determined" modal+negat ive+pass ive...dci 4G AI estCUwvVU .t "a4 icC.V UUS m 31 IT 30 A - U at9 0- U.;- W v0 IN VZW~ 0AW- 1:0- ~~~~~1 Ua tJ .2W V W~.’ wi4A :1 02scL WwU )1. 461- i A Wf

  11. Prevalence of augmented renal clearance and performance of glomerular filtration estimates in Indigenous Australian patients requiring intensive care admission.

    Science.gov (United States)

    Tsai, D; Udy, A A; Stewart, P C; Gourley, S; Morick, N M; Lipman, J; Roberts, J A

    2018-01-01

    Augmented renal clearance (ARC) refers to the enhanced renal excretion of circulating solute commonly demonstrated in numerous critically ill subgroups. This study aimed to describe the prevalence of ARC in critically ill Indigenous Australian patients and explore the accuracy of commonly employed mathematical estimates of glomerular filtration. We completed a single-centre, prospective, observational study in the intensive care unit (ICU), Alice Springs Hospital, Central Australia. Participants were critically ill adult Indigenous and non-Indigenous Australian patients with a urinary catheter in situ. Exclusion criteria were anuria, pregnancy or the requirement for renal replacement therapy. Daily eight-hour measured creatinine clearances (CrCLm) were collected throughout the ICU stay. ARC was defined by a CrCLm ≥130 ml/min/1.73 m2. The Cockcroft-Gault and Chronic Kidney Disease Epidemiology Collaboration equations were also used to calculate mathematical estimates for comparison. In total, 131 patients were recruited (97 Indigenous, 34 non-Indigenous) and 445 samples were collected. The median (range) CrCLm was 93.0 (5.14 to 205.2) and 90.4 (18.7 to 206.8) ml/min/1.73 m2 in Indigenous and non-Indigenous patients, respectively. Thirty-one of 97 (32%) Indigenous patients manifested ARC, compared to 7 of 34 (21%) non-Indigenous patients (P=0.21). Younger age, major surgery, higher baseline renal function and an absence of diabetes were all associated with ARC. Both mathematical estimates manifest limited accuracy. ARC was prevalent in critically ill Indigenous patients, which places them at significant risk of underdosing with renally excreted drugs. CrCLm should be obtained wherever possible to ensure accurate dosing.

  12. PENGARUH AKSES PELAYANAN KESEHATAN, PERFORMED TREAMENT INDEX/PTI REQUIREMENT TREATMENT INDEX/RTI, TERHADAP PERILAKU ORAL HYGIENE

    Directory of Open Access Journals (Sweden)

    Niniek L. Pratiwi

    2012-11-01

    affordability cross-subsidies required to increase purchasing power of a toothpaste containing fluoride levels and toothbrushes that can reach people, especially the poor. Key words: PTI, RTI, Perilaku Oral Hygiene, sosial ekonomi, akses pelayanan kesehatan

  13. Quantitative evaluation of yeast's requirement for glycerol formation in very high ethanol performance fed-batch process

    Directory of Open Access Journals (Sweden)

    Nevoigt Elke

    2010-05-01

    Full Text Available Abstract Background Glycerol is the major by-product accounting for up to 5% of the carbon in Saccharomyces cerevisiae ethanolic fermentation. Decreasing glycerol formation may redirect part of the carbon toward ethanol production. However, abolishment of glycerol formation strongly affects yeast's robustness towards different types of stress occurring in an industrial process. In order to assess whether glycerol production can be reduced to a certain extent without jeopardising growth and stress tolerance, the yeast's capacity to synthesize glycerol was adjusted by fine-tuning the activity of the rate-controlling enzyme glycerol 3-phosphate dehydrogenase (GPDH. Two engineered strains whose specific GPDH activity was significantly reduced by two different degrees were comprehensively characterized in a previously developed Very High Ethanol Performance (VHEP fed-batch process. Results The prototrophic strain CEN.PK113-7D was chosen for decreasing glycerol formation capacity. The fine-tuned reduction of specific GPDH activity was achieved by replacing the native GPD1 promoter in the yeast genome by previously generated well-characterized TEF promoter mutant versions in a gpd2Δ background. Two TEF promoter mutant versions were selected for this study, resulting in a residual GPDH activity of 55 and 6%, respectively. The corresponding strains were referred to here as TEFmut7 and TEFmut2. The genetic modifications were accompanied to a strong reduction in glycerol yield on glucose; the level of reduction compared to the wild-type was 61% in TEFmut7 and 88% in TEFmut2. The overall ethanol production yield on glucose was improved from 0.43 g g-1 in the wild type to 0.44 g g-1 measured in TEFmut7 and 0.45 g g-1 in TEFmut2. Although maximal growth rate in the engineered strains was reduced by 20 and 30%, for TEFmut7 and TEFmut2 respectively, strains' ethanol stress robustness was hardly affected; i.e. values for final ethanol concentration (117 ± 4 g

  14. PERFORMANCE

    Directory of Open Access Journals (Sweden)

    M Cilli

    2014-10-01

    Full Text Available This study aimed to investigate the kinematic and kinetic changes when resistance is applied in horizontal and vertical directions, produced by using different percentages of body weight, caused by jumping movements during a dynamic warm-up. The group of subjects consisted of 35 voluntary male athletes (19 basketball and 16 volleyball players; age: 23.4 ± 1.4 years, training experience: 9.6 ± 2.7 years; height: 177.2 ± 5.7 cm, body weight: 69.9 ± 6.9 kg studying Physical Education, who had a jump training background and who were training for 2 hours, on 4 days in a week. A dynamic warm-up protocol containing seven specific resistance movements with specific resistance corresponding to different percentages of body weight (2%, 4%, 6%, 8%, 10% was applied randomly on non consecutive days. Effects of different warm-up protocols were assessed by pre-/post- exercise changes in jump height in the countermovement jump (CMJ and the squat jump (SJ measured using a force platform and changes in hip and knee joint angles at the end of the eccentric phase measured using a video camera. A significant increase in jump height was observed in the dynamic resistance warm-up conducted with different percentages of body weight (p 0.05. In jump movements before and after the warm-up, while no significant difference between the vertical ground reaction forces applied by athletes was observed (p>0.05, in some cases of resistance, a significant reduction was observed in hip and knee joint angles (p<0.05. The dynamic resistance warm-up method was found to cause changes in the kinematics of jumping movements, as well as an increase in jump height values. As a result, dynamic warm-up exercises could be applicable in cases of resistance corresponding to 6-10% of body weight applied in horizontal and vertical directions in order to increase the jump performance acutely.

  15. Fermentative degradation of polyethylene glycol by a strictly anaerobic, gram-negative, nonsporeforming bacterium, Pelobacter venetianus sp. nov.

    Science.gov (United States)

    Schink, B; Stieb, M

    1983-06-01

    The synthetic polyether polyethylene glycol (PEG) with a molecular weight of 20,000 was anaerobically degraded in enrichment cultures inoculated with mud of limnic and marine origins. Three strains (Gra PEG 1, Gra PEG 2, and Ko PEG 2) of rod-shaped, gram-negative, nonsporeforming, strictly anaerobic bacteria were isolated in mineral medium with PEG as the sole source of carbon and energy. All strains degraded dimers, oligomers, and polymers of PEG up to a molecular weight of 20,000 completely by fermentation to nearly equal amounts of acetate and ethanol. The monomer ethylene glycol was not degraded. An ethylene glycol-fermenting anaerobe (strain Gra EG 12) isolated from the same enrichments was identified as Acetobacterium woodii. The PEG-fermenting strains did not excrete extracellular depolymerizing enzymes and were inhibited by ethylene glycol, probably owing to a blocking of the cellular uptake system. PEG, some PEG-containing nonionic detergents, 1,2-propanediol, 1,2-butanediol, glycerol, and acetoin were the only growth substrates utilized of a broad variety of sugars, organic acids, and alcohols. The isolates did not reduce sulfate, sulfur, thiosulfate, or nitrate and were independent of growth factors. In coculture with A. woodii or Methanospirillum hungatei, PEGs and ethanol were completely fermented to acetate (and methane). A marine isolate is described as the type strain of a new species, Pelobacter venetianus sp. nov. Its physiology and ecological significance, as well as the importance and possible mechanism of anaerobic polyether degradation, are discussed.

  16. Lack of evidence for phase-only control of retinal photoisomerization in the strict one-photon limit

    Science.gov (United States)

    Liebel, M.; Kukura, P.

    2017-01-01

    The concept of shaping electric fields to steer light-induced processes coherently has fascinated scientists for decades. Despite early theoretical considerations that ruled out one-photon coherent control (CC), several experimental studies reported that molecular responses are sensitive to the shape of the excitation field in the weak-field limit. These observations were largely attributed to the presence of rapid-decay channels, but experimental verification is lacking. Here, we test this hypothesis by investigating the degree of achievable control over the photoisomerization of the retinal protonated Schiff-base in bacteriorhodopsin, isorhodopsin and rhodopsin, all of which exhibit similar chromophores but different isomerization yields and excited-state lifetimes. Irrespective of the system studied, we find no evidence for dissipation-dependent behaviour, nor for any CC in the strict one-photon limit. Our results question the extent to which a photochemical process at ambient conditions can be controlled at the amplitude level, and how the underlying molecular potential-energy surfaces and dynamics may influence this controllability.

  17. Effect of strict metabolic control on regulation of subcutaneous blood flow in insulin-dependent diabetic patients

    DEFF Research Database (Denmark)

    Kastrup, J; Mathiesen, E R; Saurbrey, Nina

    1987-01-01

    washout technique. Mean arterial blood pressure was reduced by a maximum of 23 mmHg by elevating the limb above heart level and elevated to a maximum of 65 mmHg by head-up tilt; in the latter position venous pressure was kept constantly low by activation of the leg muscle vein pump (heel raising......The effect of 10 weeks of improved metabolic control on the impaired autoregulation of the subcutaneous blood flow was studied at the level of the lateral malleolus in eight long-term insulin-dependent diabetic patients with clinical microangiopathy. Blood flow was measured by the local 133-Xenon......). Improved metabolic control was achieved using either continuous subcutaneous insulin infusion or multiple insulin injections. The blood glucose concentration declined from (median) 12.7 to 6.8 mmol/l and the HbA1C level from 10.1 to 7.5% during strict metabolic control (p less than 0.01 and p less than 0...

  18. Building Envelope Thermal Performance Assessment Using Visual Programming and BIM, based on ETTV requirement of Green Mark and GreenRE

    Directory of Open Access Journals (Sweden)

    Taki Eddine Seghier

    2017-09-01

    Full Text Available Accomplishment of green building design requirements and the achievement of the targeted credit points under a specific green rating system are known to be a task that is very challenging. Building Information Modeling (BIM design process and tools have already made considerable advancements in green building design and performance analysis. However, Green building design process is still lack of tools and workflows that can provide real-time feedback of building sustainability and rating during the design stage. In this paper, a new workflow of green building design assessment and rating is proposed based on the integration of Visual Programing Language (VPL and BIM. Thus, the aim of this study is to develop a BIM-VPL based tool for building envelope design and assessment support. The focus performance metric in this research is building Envelope Thermal Transfer Value (ETTV which is an Energy Efficiency (EE prerequisite requirement (up to 15 credits in both Green Mark and GreenRE rating systems. The development of the tool begins first by creating a generic integration framework between BIM-VPL functionalities and ETTV requirements. Then, data is extracted from the BIM 3D model and managed using Revit, Excel and Dynamo for visual scripting. A sample project consisting of a hypothetical residential building is run and its envelope ETTV performance and rating score are obtained for the validation of the tool. This tool will support project team in building envelope design and assessment by allowing them to select the most appropriate façade configuration according to its performance efficiency and the green rating. Furthermore, this tool serves as proof of concept that building sustainability rating and compliance checking can be automatically processed through customized workflows developed based on BIM and VPL technologies.

  19. A novel strictly anaerobic recovery and enrichment system incorporating lithium for detection of heat-injured Listeria monocytogenes in pasteurized milk containing background microflora.

    Science.gov (United States)

    Mendonca, A F; Knabel, S J

    1994-11-01

    Heat-injured cells of Listeria monocytogenes were recovered from heated raw milk containing noninjured Enterococcus faecium by combining a simple method for obtaining strict anaerobiosis with a novel enrichment broth, Penn State University broth (PSU broth). Strictly anaerobic conditions were rapidly achieved by adding 0.5 g of filter-sterilized cysteine per liter to PSU broth and then purging the preparation with N2 gas. Little resuscitation or growth occurred in strictly anaerobic PSU broth without lithium chloride because of overgrowth by E. faecium. The growth of E. faecium decreased dramatically with increasing LiCl concentration; LiCl concentrations of 8 and 10 g/liter were completely bacteriostatic. The mechanism of inhibition by LiCl appeared to involve competition with the divalent cations Ca2+ and Mg2+. Heat-injured L. monocytogenes consistently recovered and grew rapidly in strictly anaerobic PSU broth containing 4, 6, or 7 g of LiCl per liter. The use of strictly anaerobic PSU broth containing 7 g of LiCl per liter permitted detection of severely heat-injured L. monocytogenes in one simple recovery-enrichment step by eliminating oxygen toxicity and inhibiting the growth of background microflora, without preventing the resuscitation and subsequent growth of heat-injured L. monocytogenes. L. monocytogenes heated in raw milk at 62.8 degrees C for 10, 15, and 20 min could be consistently recovered from strictly anaerobic PSU broth enrichment cultures at 30 degrees C after 48, 96, and 144 h, respectively, and hence, use of PSU broth may result in better recovery of both injured and noninjured cells from foods than currently used U.S. Department of Agriculture and Food and Drug Administration preenrichment procedures.

  20. Novel microsatellite DNA markers indicate strict parthenogenesis and few genotypes in the invasive willow sawfly Nematus oligospilus.

    Science.gov (United States)

    Caron, V; Norgate, M; Ede, F J; Nyman, T; Sunnucks, P

    2013-02-01

    Invasive organisms can have major impacts on the environment. Some invasive organisms are parthenogenetic in their invasive range and, therefore, exist as a number of asexual lineages (=clones). Determining the reproductive mode of invasive species has important implications for understanding the evolutionary genetics of such species, more especially, for management-relevant traits. The willow sawfly Nematus oligospilus Förster (Hymenoptera: Tenthredinidae) has been introduced unintentionally into several countries in the Southern Hemisphere where it has subsequently become invasive. To assess the population expansion, reproductive mode and host-plant relationships of this insect, microsatellite markers were developed and applied to natural populations sampled from the native and expanded range, along with sequencing of the cytochrome-oxidase I mitochondrial DNA (mtDNA) region. Other tenthredinids across a spectrum of taxonomic similarity to N. oligospilus and having a range of life strategies were also tested. Strict parthenogenesis was apparent within invasive N. oligospilus populations throughout the Southern Hemisphere, which comprised only a small number of genotypes. Sequences of mtDNA were identical for all individuals tested in the invasive range. The microsatellite markers were used successfully in several sawfly species, especially Nematus spp. and other genera of the Nematini tribe, with the degree of success inversely related to genetic divergence as estimated from COI sequences. The confirmation of parthenogenetic reproduction in N. oligospilus and the fact that it has a very limited pool of genotypes have important implications for understanding and managing this species and its biology, including in terms of phenotypic diversity, host relationships, implications for spread and future adaptive change. It would appear to be an excellent model study system for understanding evolution of invasive parthenogens that diverge without sexual reproduction and

  1. Sporothrix schenckii (sensu strict S. globosa) mating type 1-2 (MAT1-2) gene.

    Science.gov (United States)

    Kano, Rui; Anzawa, Kazushi; Mochizuki, Takashi; Nishimoto, Katsutaro; Hiruma, Masataro; Kamata, Hiroshi; Hasegawa, Atsuhiko

    2013-09-01

    Sporotix schenckii is a pathogenic fungus that causes human and animal sporotrichosis, and based on morphology of the sessile conidia and molecular analysis, it was recently recognized as a species complex comprising at least the following six sibling species: S. albicans, S. brasiliensis, S. globosa, S. luriei, S. mexicana and S. schenckii. However, apart from S. schenckii sensu strict, only S. brasiliensis, S. globosa and S. luriei are associated with human and animal infection. S. globosa has been most commonly isolated in Asia, Europe and the USA; therefore, molecular epidemiological study for S. globosa is important in relation to human sporotrichosis in Japan. To the best of our knowledge, this is the first study to determine the mating type 1-2 (MAT1-2) gene of Sporothrix schenckii with the aim of understanding the taxonomy of the genus Sporothrix. The MAT1-2 gene (1618 bp) encodes a protein sequence of 198 amino acids. Reverse transcription polymerase chain reaction analysis also detected MAT1-2 gene mRNA expression in all of the S. schenckii strains examined, indicating that this gene is expressed in S. schenckii cells. Phylogenetic analysis of the MAT1-2 gene fragments of Ophiostoma himal-ulmi, O. novo-ulmi, O. ulmi and S. schenckii indicated that these isolates could be classified into four clusters. MAT1-1 gene-specific polymerase chain reaction was positive in 15 isolates, but negative in four human isolates and one feline isolate. © 2013 Japanese Dermatological Association.

  2. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) ; Guidance on the scientific requirements for health claims related to physical performance

    DEFF Research Database (Denmark)

    Tetens, Inge

    The Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked by the European Food Safety Authority (EFSA) to draft guidance on scientific requirements for health claims related to physical performance. This guidance has been drawn from scientific opinions of the NDA Panel on such health...... claims. Thus, this guidance document represents the views of the NDA Panel based on the experience gained to date with the evaluation of health claims in this area. It is not intended that the document should include an exhaustive list of beneficial effects and studies/outcome measures which...

  3. Work in support of biosphere assessments for solid radioactive waste disposal. 1. performance assessments, requirements and methodology; criteria for radiological environmental protection

    International Nuclear Information System (INIS)

    Egan, M.J.; Loose, M.; Smith, G.M.; Watkins, B.M.

    2001-10-01

    The first part of this report is intended to assess how the recent Swedish regulatory developments and resulting criteria impose requirements on what should be included in a performance assessment (PA) for the SFR low and medium level waste repository and for a potential deep repository for high level waste. The second part of the report has been prepared by QuantiSci as an input to the development of SSI's PA review methodology. The aim of the third part is to provide research input to the development of radiological protection framework for the environment, for use in Sweden. This is achieved through a review of various approaches used in other fields

  4. Quality requirements for veterinary hematology analyzers in small animals-a survey about veterinary experts' requirements and objective evaluation of analyzer performance based on a meta-analysis of method validation studies: bench top hematology analyzer.

    Science.gov (United States)

    Cook, Andrea M; Moritz, Andreas; Freeman, Kathleen P; Bauer, Natali

    2016-09-01

    Scarce information exists about quality requirements and objective evaluation of performance of large veterinary bench top hematology analyzers. The study was aimed at comparing the observed total error (TEobs ) derived from meta-analysis of published method validation data to the total allowable error (TEa ) for veterinary hematology variables in small animals based on experts' opinions. Ideally, TEobs should be hematology analyzers (ADVIA 2120; Sysmex XT2000iV, and CellDyn 3500) was calculated based on method validation studies published between 2005 and 2013 (n = 4). The percent TEobs = 2 * CV (%) + bias (%). The CV was derived from published studies except for the ADVIA 2120 (internal data), and bias was estimated from the regression equation. A total of 41 veterinary experts (19 diplomates, 8 residents, 10 postgraduate students, 4 anonymous specialists) responded. The proposed range of TEa was wide, but generally ≤ 20%. The TEobs was < TEa for all variables and analyzers except for canine and feline HGB (high bias, low CV) and platelet counts (high bias, high CV). Overall, veterinary bench top analyzers fulfilled experts' requirements except for HGB due to method-related bias, and platelet counts due to known preanalytic/analytic issues. © 2016 American Society for Veterinary Clinical Pathology.

  5. Enrichment of HLA Types and Single-Nucleotide Polymorphism Associated With Non-progression in a Strictly Defined Cohort of HIV-1 Controllers

    Directory of Open Access Journals (Sweden)

    Samantha J. Westrop

    2017-06-01

    Full Text Available HIV-1 controllers (HIC are extremely rare patients with the ability to control viral replication, maintain unchanging CD4 T-cell count, and evade disease progression for extensive periods of time, in the absence of antiretroviral therapy. In order to establish the representation of key genetic correlates of atypical disease progression within a cohort of HIV-1+ individuals who control viral replication, we examine four-digit resolution HLA type and single-nucleotide polymorphisms (SNP previously identified to be correlated to non-progressive infection, in strictly defined HIC. Clinical histories were examined to identify patients exhibiting HIC status. Genomic DNA was extracted, and high definition HLA typing and genome-wide SNP analysis was performed. Data were compared with frequencies of SNP in European long-term non-progressors (LTNP and primary infection cohorts. HLA-B alleles associated with atypical disease progression were at very high frequencies in the group of five HIC studied. All four HIC of European ancestry were HLA-B*57+ and half were also HLA-B*27+. All HIC, including one of self-reported African ethnicity, had the HLA-Cw*0602 allele, and the HLA-DQ9 allele was present only in HIC of European ancestry. A median 95% of the top 19 SNP known to be associated with LTNP status was observed in European HIC (range 78–100%; 17/19 of the SNP considered mapped to chromosome 6 in the HLA region, whereas 2/19 mapped to chromosome 8. The HIC investigated here demonstrated high enrichment of HLA types and SNP previously associated with long-term non-progression. These findings suggest that the extreme non-progressive phenotype considered here is associated with a genetic signature characterized by a single-genetic unit centered around the HLA-B*57 haplotype and the possible additive effect of HLA-B*27.

  6. Optimization of an effective growth medium for culturing probiotic bacteria for applications in strict vegetarian food products

    Directory of Open Access Journals (Sweden)

    Manju Pathak

    2012-10-01

    Full Text Available Background: This study aimed to modify de Man Rogosa Sharpe culture medium (termed MRS for selective cultivation of probiotics strain for the consumption by the strictly vegetarian human population. Vegetarian probiotic foods by definition must be free from all animal-derived ingredients. This not only includes the product ingredients but the probiotic inoculum as well. Probiotic starter cultures are traditionally grown and stored in media containing milk or meatderived ingredients. The presence of these ingredients makes the probiotic cell concentrates unsuitable for use in vegetarian products and thus creates the need for a growth medium which isfree from animal-derived ingredients. Present study investigated the growth of a strain of Lactobacillus lactis in MRS. The present invention relates in general to a bacterial culture media,and more specifically a complex microbial culture media, based on plant seed powder extract in place of animal extract for probiotic bacterial growth.Methods: Lactobacillus lactis, a probiotic, was grown in standard MRS culture medium as well as in our various test media (TM containing various vegetal source in place of beef extract, yeast extract and peptone as in case of MRS. The inoculated culture mediums were incubated at 37C for 72 hours and growth of probiotic is recorded at regular intervals. The growth was recorded as Colony Forming Units (CFUs.Results: The best growth of probiotic is observed in TM 2. TM 2 is the leguminous seed extract. Starter culture mediums for probiotics or other bacteria primarily contain protein from animal source. The possibility of using vegetal protein from TM 2 extract in place of peptones and meat extract for the nitrogen supplementation of culture media for the growth of lactic acid bacteria has been demonstrated.Functional Foods in Health and Disease 2012, 2(10:369-378 Conclusion: The absolute vegetarian culture medium containing TM 2 is better than standard MRS for the

  7. Lenient vs. strict rate control in patients with atrial fibrillation and heart failure: a post-hoc analysis of the RACE II study

    NARCIS (Netherlands)

    Mulder, Bart A.; van Veldhuisen, Dirk J.; Crijns, Harry J. G. M.; Tijssen, Jan G. P.; Hillege, Hans L.; Alings, Marco; Rienstra, Michiel; Groenveld, Hessel F.; van den Berg, Maarten P.; van Gelder, Isabelle C.

    2013-01-01

    It is unknown whether lenient rate control is an acceptable strategy in patients with AF and heart failure. We evaluated differences in outcome in patients with AF and heart failure treated with lenient or strict rate control. This post-hoc analysis of the RACE II trial included patients with an

  8. A Banach-Dieudonné theorem for the space of bounded continuous functions on a separable metric space with the strict topology

    NARCIS (Netherlands)

    Kraaij, R.C.

    2016-01-01

    Let X be a separable metric space and let β be the strict topology on the space of bounded continuous functions on X, which has the space of τ-additive Borel measures as a continuous dual space. We prove a Banach-Dieudonné type result for the space of bounded continuous functions equipped with β:

  9. Requirements for existing buildings

    DEFF Research Database (Denmark)

    Thomsen, Kirsten Engelund; Wittchen, Kim Bjarne

    This report collects energy performance requirements for existing buildings in European member states by June 2012.......This report collects energy performance requirements for existing buildings in European member states by June 2012....

  10. Work in support of biosphere assessments for solid radioactive waste disposal. 1. performance assessments, requirements and methodology; criteria for radiological environmental protection

    Energy Technology Data Exchange (ETDEWEB)

    Egan, M.J.; Loose, M.; Smith, G.M.; Watkins, B.M. [QuantiSci Ltd., Henley-on-Thames (United Kingdom)

    2001-10-01

    The first part of this report is intended to assess how the recent Swedish regulatory developments and resulting criteria impose requirements on what should be included in a performance assessment (PA) for the SFR low and medium level waste repository and for a potential deep repository for high level waste. The second part of the report has been prepared by QuantiSci as an input to the development of SSI's PA review methodology. The aim of the third part is to provide research input to the development of radiological protection framework for the environment, for use in Sweden. This is achieved through a review of various approaches used in other fields.

  11. The "high solubility" definition of the current FDA Guidance on Biopharmaceutical Classification System may be too strict for acidic drugs.

    Science.gov (United States)

    Yazdanian, Mehran; Briggs, Katherine; Jankovsky, Corinne; Hawi, Amale

    2004-02-01

    The purpose of this study was to assess if the definition of high solubility as proposed in the FDA Guidance on Biopharmaceutical Classification System (BCS) is too strict for highly permeable acidic drugs. The solubility and permeability values of 20 (18 acidic and 2 non-acidic) nonsteroidal anti-inflammatory drugs (NSAID) were determined. The NSAIDs were grouped into three different sets having acetic acid, propionic acid, or other acidic moieties such as fenamate, oxicam, and salicylate. Two nonacidic NSAIDs (celecoxib and rofecoxib) were also included for comparison purposes. Equilibrium solubility values were determined at pH 1.2, 5.0, 7.4, and in biorelevant media simulating fed intestinal fluid at pH 5.0. For a select number of acids, we also measured solubility values in media simulating gastric and fasted intestinal fluids. Permeability classification was established relative to that of reference drugs in the Caco-2 cell permeability model. Permeability coefficients for all drugs were measured at concentrations corresponding to the lowest and highest marketed dose strengths dissolved in 250 ml volume, and their potential interaction with cellular efflux pumps was investigated. All NSAIDs with different acidic functional groups were classified as highly permeable based on their Caco-2 cell permeability. Only ketorolac appeared to have a potential for interaction with cellular efflux pumps. Solubility classification was based on comparison of equilibrium solubility at pH 1.2, 5.0. and 7.4 relative to marketed dose strengths in 250 ml. The pKa values for the acidic NSAIDs studied were between 3.5 and 5.1. and, as expected, their solubility increased dramatically at pH 7.4 compared to pH 1.2. Only three NSAIDs, ketorolac, ketoprofen. and acetyl salicylic acid, meet the current criteria for high solubility over the entire pH range. However, with the exception of ibuprofen, oxaprozin, and mefenamic acid, the remaining compounds can be classified as Class I drugs

  12. An Analysis of the Acquisition Process for Simplified Acquisition of Base Engineering Requirements (SABER) Contracts and Its Potential Impact on Contractor Performance

    National Research Council Canada - National Science Library

    Heaps, Brian

    2001-01-01

    The Simplified Acquisition of Base Engineering Requirements (SABER) contract's main purpose is to expedite contract award of civil engineer requirements through the issuance of individual delivery orders...

  13. Partial QoS-Aware Opportunistic Relay Selection Over Two-Hop Channels: End-to-End Performance Under Spectrum-Sharing Requirements

    KAUST Repository

    Yuli Yang,

    2014-10-01

    In this paper, we propose a partial quality-of-service (QoS)-oriented relay selection scheme with a decode-and-forward (DF) relaying protocol, to reduce the feedback amount required for relay selection. In the proposed scheme, the activated relay is the one with the maximum signal-to-noise power ratio (SNR) in the second hop among those whose packet loss rates (PLRs) in the first hop achieve a predetermined QoS level. For the purpose of evaluating the performance of the proposed scheme, we exploit it with transmission constraints imposed on the transmit power budget and interference to other users. By analyzing the statistics of received SNRs in the first and second hops, we obtain the end-to-end PLR of this scheme in closed form under the considered scenario. Moreover, to compare the proposed scheme with popular relay selection schemes, we also derive the closed-form PLR expressions for partial relay selection (PRS) and opportunistic relay selection (ORS) criteria in the same scenario under study. Illustrative numerical results demonstrate the accuracy of our derivations and substantiate that the proposed relay selection scheme is a promising alternative with respect to the tradeoff between performance and complexity.

  14. Comparison between mechanical power requirements of flight estimated using an aerodynamic model and in vitro muscle performance in the cockatiel (Nymphicus hollandicus).

    Science.gov (United States)

    Morris, Charlotte R; Askew, Graham N

    2010-08-15

    There have been few comparisons between the relationship between the mechanical power requirements of flight and flight speed obtained using different approaches. It is unclear whether differences in the power-speed relationships reported in the literature are due to the use of different techniques for determining flight power or due to inter-specific differences. Here we compare the power-speed relationships in cockatiels (Nymphicus hollandicus) determined using both an aerodynamic model and measurements of in vitro performance of bundles of pectoralis muscle fibres under simulated in vivo strain and activity patterns. Aerodynamic power was calculated using different ranges of values for the coefficients in the equations: induced power factor (k 1.0-1.4), the profile (C(D, pro) 0.01-0.03) and parasite drag (C(D, par) 0.05-0.195) coefficients. We found that the aerodynamic power-speed relationship was highly sensitive to the values assumed for these coefficients and best fit the power calculated from in vitro muscle performance when k=1.2, C(D, pro)=0.02 and C(D, par)=0.13.

  15. Association Between Flexible Duty Hour Policies and General Surgery Resident Examination Performance: A Flexibility in Duty Hour Requirements for Surgical Trainees (FIRST) Trial Analysis.

    Science.gov (United States)

    Blay, Eddie; Hewitt, D Brock; Chung, Jeanette W; Biester, Thomas; Fiore, James F; Dahlke, Allison R; Quinn, Christopher M; Lewis, Frank R; Bilimoria, Karl Y

    2017-02-01

    Concerns persist about the effect of current duty hour reforms on resident educational outcomes. We investigated whether a flexible, less-restrictive duty hour policy (Flexible Policy) was associated with differential general surgery examination performance compared with current ACGME duty hour policy (Standard Policy). We obtained examination scores on the American Board of Surgery In-Training Examination, Qualifying Examination (written boards), and Certifying Examination (oral boards) for residents in 117 general surgery residency programs that participated in the Flexibility in Duty Hour Requirements for Surgical Trainees (FIRST) Trial. Using bivariate analyses and regression models, we compared resident examination performance across study arms (Flexible Policy vs Standard Policy) for 2015 and 2016, and 1 year of the Qualifying Examination and Certifying Examination. Adjusted analyses accounted for program-level factors, including the stratification variable for randomization. In 2016, FIRST trial participants were 4,363 general surgery residents. Mean American Board of Surgery In-Training Examination scores for residents were not significantly different between study groups (Flexible Policy vs Standard Policy) overall (Flexible Policy: mean [SD] 502.6 [100.9] vs Standard Policy: 502.7 [98.6]; p = 0.98) or for any individual postgraduate year level. There was no difference in pass rates between study arms for either the Qualifying Examination (Flexible Policy: 90.4% vs Standard Policy: 90.5%; p = 0.99) or Certifying Examination (Flexible Policy: 86.3% vs Standard Policy: 88.6%; p = 0.24). Results from adjusted analyses were consistent with these findings. Flexible, less-restrictive duty hour policies were not associated with differences in general surgery resident performance on examinations during the FIRST Trial. However, more years under flexible duty hour policies might be needed to observe an effect. Copyright © 2016 American College of Surgeons

  16. Peculiarities of one-carbon metabolism in the strict carnivorous cat and the role in feline hepatic lipidosis.

    Science.gov (United States)

    Verbrugghe, Adronie; Bakovic, Marica

    2013-07-19

    Research in various species has indicated that diets deficient in labile methyl groups (methionine, choline, betaine, folate) produce fatty liver and links to steatosis and metabolic syndrome, but also provides evidence of the importance of labile methyl group balance to maintain normal liver function. Cats, being obligate carnivores, rely on nutrients in animal tissues and have, due to evolutionary pressure, developed several physiological and metabolic adaptations, including a number of peculiarities in protein and fat metabolism. This has led to specific and unique nutritional requirements. Adult cats require more dietary protein than omnivorous species, maintain a consistently high rate of protein oxidation and gluconeogenesis and are unable to adapt to reduced protein intake. Furthermore, cats have a higher requirement for essential amino acids and essential fatty acids. Hastened use coupled with an inability to conserve certain amino acids, including methionine, cysteine, taurine and arginine, necessitates a higher dietary intake for cats compared to most other species. Cats also seemingly require higher amounts of several B-vitamins compared to other species and are predisposed to depletion during prolonged inappetance. This carnivorous uniqueness makes cats more susceptible to hepatic lipidosis.

  17. Peculiarities of One-Carbon Metabolism in the Strict Carnivorous Cat and the Role in Feline Hepatic Lipidosis

    Directory of Open Access Journals (Sweden)

    Marica Bakovic

    2013-07-01

    Full Text Available Research in various species has indicated that diets deficient in labile methyl groups (methionine, choline, betaine, folate produce fatty liver and links to steatosis and metabolic syndrome, but also provides evidence of the importance of labile methyl group balance to maintain normal liver function. Cats, being obligate carnivores, rely on nutrients in animal tissues and have, due to evolutionary pressure, developed several physiological and metabolic adaptations, including a number of peculiarities in protein and fat metabolism. This has led to specific and unique nutritional requirements. Adult cats require more dietary protein than omnivorous species, maintain a consistently high rate of protein oxidation and gluconeogenesis and are unable to adapt to reduced protein intake. Furthermore, cats have a higher requirement for essential amino acids and essential fatty acids. Hastened use coupled with an inability to conserve certain amino acids, including methionine, cysteine, taurine and arginine, necessitates a higher dietary intake for cats compared to most other species. Cats also seemingly require higher amounts of several B-vitamins compared to other species and are predisposed to depletion during prolonged inappetance. This carnivorous uniqueness makes cats more susceptible to hepatic lipidosis.

  18. Compatibilidade entre exigências do mercado industrial e desempenho dos alunos de administração = Compatibility with industrial requirements and the performance of administration students

    Directory of Open Access Journals (Sweden)

    Leonardo Stephanin

    2017-07-01

    requirements of the administrator. Subsequently, a semi-structured questionnaire with 35 closed and one open ended questions was answered by 24 students in the last year of Administration in order to diagnose the performance in relation to contents given in class and inquired by companies. In the second stage, through an interview with the principal, it was diagnosed the position of the institution before the course and the market. The results revealed that there is a significant divergence between the two scopes, but themes such as the marketing mix strategies and the Customer Relantionship Management [CRM] tool stood out positively both in the industry requirements and in the performance of the students. In the same way, the Materials Requirements Planning [MRP] tool and the methods of the industrial location excelled in negative aspect and also being repeated in the two visions.

  19. MORA DEBITORIS AND THE PRINCIPLE OF STRICT LIABILITY: SCOIN TRADING (PTY LTD V BERNSTEIN 2011 2 SA 118 (SCA

    Directory of Open Access Journals (Sweden)

    SJ Cornelius

    2012-12-01

    Full Text Available Parties generally enter into contractual relations with the sincere intention to fulfil all the obligations created in terms of their contract. However, for various reasons, parties sometimes do not comply with the terms of their contract. Where a party fails to perform at the agreed date and time or after receiving a demand from the creditor, the debtor commits breach of contract in the form of mora debitoris. The question then arises whether or not a debtor would also commit breach in the form of mora debitoris if the delay in performance cannot be attributed to wilful disregard of the contract or a negligent failure to perform on time. This was the question which the court had to determine in Scoin Trading (Pty Ltd v Bernstein.

  20. Value management : functional expression of the need and functional performance specification : requirements for expressing and validating the need to be satisfied within the process of purchasing or obtaining a product

    CERN Document Server

    Association Française de Normalisation. Paris

    2013-01-01

    Value management : functional expression of the need and functional performance specification : requirements for expressing and validating the need to be satisfied within the process of purchasing or obtaining a product

  1. Performance study of hybrid photon detectors for the LHCb RICH

    International Nuclear Information System (INIS)

    Kanaya, N.; Aglieri-Rinella, G.; Gys, T.; Piedigrossi, D.; Wyllie, K.

    2005-01-01

    The LHCb experiment is designed to study CP violation and rare phenomena of B mesons with very high accuracy. The LHCb RICH detectors are essential for positive kaon identification, and several strict demands are required of its photon detectors to achieve excellent particle identification performance. In particular, they should have good single photon sensitivity for visible and UV wavelengths and large coverage with fine granularity. HPDs have been developed to meet these requirements in collaboration with industry. They have now been chosen as the photon detector for LHCb, and pre-series tubes are under test prior to mass production. At the same time, more detailed studies are on-going to understand more deeply their characteristics. The result of various performance tests of these tubes as well as the fraction of light reflection in the HPD are described in this paper

  2. Towards High Performance Processing In Modern Java Based Control Systems

    CERN Document Server

    Misiowiec, M; Buttner, M

    2011-01-01

    CERN controls software is often developed on Java foundation. Some systems carry out a combination of data, network and processor intensive tasks within strict time limits. Hence, there is a demand for high performing, quasi real time solutions. Extensive prototyping of the new CERN monitoring and alarm software required us to address such expectations. The system must handle dozens of thousands of data samples every second, along its three tiers, applying complex computations throughout. To accomplish the goal, a deep understanding of multithreading, memory management and interprocess communication was required. There are unexpected traps hidden behind an excessive use of 64 bit memory or severe impact on the processing flow of modern garbage collectors. Tuning JVM configuration significantly affects the execution of the code. Even more important is the amount of threads and the data structures used between them. Accurately dividing work into independent tasks might boost system performance. Thorough profili...

  3. The tendency of medical electrical equipment - IEC 60601-2-54: Particular requirements for the basic safety and essential performance of x-ray equipment for radiography and radioscopy

    International Nuclear Information System (INIS)

    Roh, Young Hoon; Kim, Jung Min

    2015-01-01

    Medical electrical equipment - Part 1: General requirement for basic safety and essential performance of MFDS was revised as 3th edition and Medical electrical equipment Part 2-54: Particular requirements for the basic safety and essential performance of X-ray equipment will be expected to be announced as notification. Therefore this technical report was written to introduce provision of the particular requirements, replacement, addition, amendment. The purpose of this particular requirements is to secure requirements for basic safety and essential performance of X-ray equipment for radiography and radioscopy. X-ray high voltage generator, mechanical protective device, protection against radiation is included in this particular requirements. Medical electrical equipment - Part 1, Part 1-2, Part 1-3 is applied to this particular requirements. If the requirements is announced as notification, It is expected to widen understanding for basic safety and essential performance of X-ray equipment for radiography and radioscopy and play a part to internationalize of medical equipment

  4. Infectious Gastroenteritis and the Need for Strict Contact Precaution Procedures in Adults Presenting in the Emergency Department

    DEFF Research Database (Denmark)

    Skyum, Florence; Andersen, Vibeke; Chen, Ming

    2018-01-01

    BACKGROUND: Acute infectious gastroenteritis requires contact precautions to prevent spreading. On acute admission the cause of diarrhoea is unknown, so the decision of whom to isolate has to be made on clinical information with a risk of inexpedient use of contact precautions. AIM: The aims...... of the study were to investigate how often gastroenteritis occurs, and thus the isolation indication has to be assessed, in Danish emergency departments, and how often patients have to remain on contact precaution according to the results of the faecal samples. METHODS: This Danish register based retrospective......: Among 66,885 acute admissions 4.3% patients had at least one feature of gastroenteritis: admission with a chief complaint of diarrhoea (1.6%); faecal sample microbiology examination (2.8%); discharged with a gastroenteritis diagnosis (1.7%). 19% of those who had a faecal sample tested were norovirus...

  5. Musical Formalism and Political Performances

    Directory of Open Access Journals (Sweden)

    Jonathan A. Neufeld

    2009-01-01

    Full Text Available Musical formalism, which strictly limits the type of thing any description of the music can tell us, is ill-equipped to account for contemporary performance practice. If performative interpretations are in a position to tell us something about musical works—that is if performance is a kind of description, as Peter Kivy argues—then we have to loosen the restrictions on notions of musical relevance to make sense of performance. I argue that musical formalism, which strictly limits the type of thing any description of the music can tell us, is inconsistent with Kivy's quite compelling account of performance. This shows the difficulty that actual performances pose to overly rigid conceptions of music. Daniel Barenboim's unannounced performance of Wagner in Israel in 2001 shows that the problem of the boundaries of musical relevance is no mere philosophical puzzle. It is a pressing problem in the musical public sphere.

  6. High Performance Single Nanowire Tunnel Diodes

    DEFF Research Database (Denmark)

    Wallentin, Jesper; Persson, Johan Mikael; Wagner, Jakob Birkedal

    Semiconductor nanowires (NWs) have emerged as a promising technology for future electronic and optoelectronic devices. Epitaxial growth of III-V materials on Si substrates have been demonstrated, allowing for low-cost production. As the lattice matching requirements are much less strict than...... for planar growth, many new materials combinations can be grown in a single NW. This opens up exciting opportunities for NW-based high-performance solar cells, where previously inaccessible materials combinations can now be chosen to match the solar spectrum. A key component of a multi-junction solar cell...... NWs were contacted in a NW-FET setup. Electrical measurements at room temperature display typical tunnel diode behavior, with a Peak-to-Valley Current Ratio (PVCR) as high as 8.2 and a peak current density as high as 329 A/cm2. Low temperature measurements show improved PVCR of up to 27.6....

  7. Harmonized Constraints in Software Engineering and Acquisition Process Management Requirements are the Clue to Meet Future Performance Goals Successfully in an Environment of Scarce Resources

    National Research Council Canada - National Science Library

    Reich, Holger

    2008-01-01

    This MBA project investigates the importance of correctly deriving requirements from the capability gap and operational environment, and translating them into the processes of contracting, software...

  8. Seamless Requirements

    OpenAIRE

    Naumchev, Alexandr; Meyer, Bertrand

    2017-01-01

    Popular notations for functional requirements specifications frequently ignore developers' needs, target specific development models, or require translation of requirements into tests for verification; the results can give out-of-sync or downright incompatible artifacts. Seamless Requirements, a new approach to specifying functional requirements, contributes to developers' understanding of requirements and to software quality regardless of the process, while the process itself becomes lighter...

  9. Sorption-induced reversible oxidation of Fe(2) at the smectite/water interface under strictly anoxic conditions. A Moessbauer spectroscopy study

    Energy Technology Data Exchange (ETDEWEB)

    Gehin, A.; Charlet, L. [Laboratoire de Geophysique Interne et Tectonophysique (LGIT), Universite de Grenoble, 38 - Grenoble (France); Gehin, A. [Agence Nationale pour la Gestion des Dechets Radioactifs, ANDRA, 92 - Chatenay Malabry (France); Greneche, J.M. [Laboratoire de Physique de l' Etat Condense, UMR-CNRS 6087, 72 - Le Mans (France); Brendle, J. [Universite de Haute Alsace, Lab. des Materiaux Mineraux (LMM), 68 - Mulhouse (France); Rancourt, D.G. [Ottawa Univ., Dept. of Physics, Ontario (Canada)

    2005-07-01

    Previous studies of Fe(II) sorption onto montmorillonite have been performed with the mineral extracted from the MX80 bentonite. These studies have shown that Fe(II) can be sorbed onto clay minerals in cation exchange position. The affinity of montmorillonite for Fe(II) and Ca(II) is identical. Fe(II) may also be specifically adsorbed onto montmorillonite clay edges. Moessbauer spectroscopy confirmed the high affinity of clay surfaces for Fe(II) sorption and showed that this sorption is mainly due to a two step mechanism: Fe(II) specific adsorption, followed by oxidation of the Fe(II) sorbed. The identification of the oxidizing agent was prohibited due to the complex chemistry of the natural MX80 montmorillonite. Thus, synthetic iron-free montmorillonite was used (chemical formula: Ca{sub 0.3} (A{sub 1.4}Mg{sub 0.6}) (Si{sub 4}) O{sub 10}(OH){sub 2} ). {sup 57}Fe(II) sorption experiments were conducted in a N{sub 2} atmosphere gloves-box, in strictly anoxic conditions. Solid samples were synthesized in order to confirm the clay high affinity for Fe(II), in absence of structural oxidant, and to have a better comprehension of the sorption mechanism. Moessbauer spectra were recorded for each sample. Whereas no Fe(III) is detected in solution as pH was increased and then, a significant amount of surface sorbed Fe(III) was found to be reversibly produced, which amounts for 0-3% of total Fe in the pre-sorption edge acid region, up to 7% of total Fe when all Fe is sorbed in the neutral to alkaline pH range. From pH {approx_equal} 2 to pH {approx_equal} 7, a sorption edge plateau is observed. In this plateau, the sorbed-Fe(III)/sorbed-Fe ratio increases with pH, up to 45% at pH 7. Moessbauer spectra comparison with ferrous hydroxide, synthesized in the same redox conditions at higher pH, show that this oxidation can not be due to the trace amounts Oz in the suspension. The Moessbauer spectra components of both Fe(II) and Fe(III) appears as paramagnetic doublets: iron has

  10. Legal consequences of not performing requisite pre-anaesthesia test

    Directory of Open Access Journals (Sweden)

    2008-01-01

    Full Text Available Suggested Precautions Perform sensitive test before giving anaesthesia and specifically record the said fact in pre-operative notes.Necessary precautions prescribed and followed in medicine must be strictly followed and duly recorded.

  11. The balanced scorecard: an integrative approach to performance evaluation.

    Science.gov (United States)

    Oliveira, J

    2001-05-01

    In addition to strict financial outcomes, healthcare financial managers should assess intangible assets that affect the organization's bottom line, such as clinical processes, staff skills, and patient satisfaction and loyalty. The balanced scorecard, coupled with data-warehousing capabilities, offers a way to measure an organization's performance against its strategic objectives while focusing on building capabilities to achieve these objectives. The balanced scorecard examines performance related to finance, human resources, internal processes, and customers. Because the balanced scorecard requires substantial amounts of data, it is a necessity to establish an organizational data warehouse of clinical, operational, and financial data that can be used in decision support. Because it presents indicators that managers and staff can influence directly by their actions, the balanced-scorecard approach to performance measurement encourages behavioral changes aimed at achieving corporate strategies.

  12. High performance computing system in the framework of the Higgs boson studies

    CERN Document Server

    Belyaev, Nikita; The ATLAS collaboration; Velikhov, Vasily; Konoplich, Rostislav

    2017-01-01

    The Higgs boson physics is one of the most important and promising fields of study in the modern high energy physics. It is important to notice, that GRID computing resources become strictly limited due to increasing amount of statistics, required for physics analyses and unprecedented LHC performance. One of the possibilities to address the shortfall of computing resources is the usage of computer institutes' clusters, commercial computing resources and supercomputers. To perform precision measurements of the Higgs boson properties in these realities, it is also highly required to have effective instruments to simulate kinematic distributions of signal events. In this talk we give a brief description of the modern distribution reconstruction method called Morphing and perform few efficiency tests to demonstrate its potential. These studies have been performed on the WLCG and Kurchatov Institute’s Data Processing Center, including Tier-1 GRID site and supercomputer as well. We also analyze the CPU efficienc...

  13. Kinesthetic imagery of musical performance

    Directory of Open Access Journals (Sweden)

    Martin eLotze

    2013-06-01

    Full Text Available Musicians use different kinds of imagery. This review focuses on kinesthetic imagery, which has been shown to be an effective complement to actively playing an instrument. However, experience in actual movement performance seems to be a requirement for a recruitment of those brain areas representing movement ideation during imagery. An internal model of movement performance might be more differentiated when training has been more intense or simply performed more often. Therefore, with respect to kinesthetic imagery, these strategies are predominantly found in professional musicians. There are a few possible reasons as to why kinesthetic imagery is used in addition to active training; one example is the need for mental rehearsal of the technically most difficult passages. Training difficult passages repeatedly has the potential to induce fatigue in tendons and muscles and can ultimately result in the development of dystonia. Another reason for mental practice is that mental rehearsal of the piece helps to improve performance if the instrument is not available for actual training as is the case for professional musicians when they are travelling to various appearances. Overall, mental imagery in musicians is not necessarily specific to motor, somatosensory, auditory or visual aspects of imagery, but integrates them all. In particular, the audiomotor loop is highly important, since auditory aspects are crucial for guiding motor performance. Furthermore, slight co-movement, for instance of the fingers, usually occurs when imagining musical performance, a situation different to the laboratory condition where movement execution is strictly controlled. All these aspects result in a distinctive representation map for the mental imagery of musical performance. This review summarizes behavioral data, and findings from functional brain imaging studies of mental imagery of musical performance.

  14. Performance Exploring the Role of Pianists' Emotional Engagement ...

    African Journals Online (AJOL)

    The results suggest that performers experience two categories of emotions during performance: musical emotions relating to the emotional content of the music, and performance-related emotions relating to performance circumstances. Performers maintain strict control of both categories of emotions in optimal performance.

  15. Minimal requirements for quality controls in radiotherapy with external beams

    International Nuclear Information System (INIS)

    1999-01-01

    Physical dosimetric guidelines have been developed by the Italian National Institute of Health study group on quality assurance in radiotherapy to define protocols for quality controls in external beam radiotherapy. While the document does not determine strict rules or firm recommendations, it suggests minimal requirements for quality controls necessary to guarantee an adequate degree of accuracy in external beam radiotherapy [it

  16. 18 CFR 358.4 - Non-discrimination requirements.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Non-discrimination... Non-discrimination requirements. (a) A transmission provider must strictly enforce all tariff... (including, but not limited to, issues of price, curtailments, scheduling, priority, ancillary services, or...

  17. 40 CFR Table 11 to Subpart Uuu of... - Requirements for Performance Tests for Organic HAP Emissions From Catalytic Cracking Units Not...

    Science.gov (United States)

    2010-07-01

    ... Refineries: Catalytic Cracking Units, Catalytic Reforming Units, and Sulfur Recovery Units Pt. 63, Subpt. UUU... Organic HAP Emissions From Catalytic Cracking Units Not Subject to New Source Performance Standard (NSPS... From Catalytic Cracking Units Not Subject to New Source Performance Standard (NSPS) for Carbon Monoxide...

  18. 40 CFR Table 4 to Subpart Uuu of... - Requirements for Performance Tests for Metal HAP Emissions From Catalytic Cracking Units Not...

    Science.gov (United States)

    2010-07-01

    ... Petroleum Refineries: Catalytic Cracking Units, Catalytic Reforming Units, and Sulfur Recovery Units Pt. 63... Metal HAP Emissions From Catalytic Cracking Units Not Subject to the New Source Performance Standard... Emissions From Catalytic Cracking Units Not Subject to the New Source Performance Standard (NSPS) for...

  19. Energy and economic evaluation of the single-family residential building energy performance standards

    Energy Technology Data Exchange (ETDEWEB)

    O' Neal, D.L.; Jones, J.L.

    1981-11-01

    The Energy Production and Conservation Act (EPCA) of 1976 mandated the setting of building energy performance standards (BEPS) for all newly constructed buildings. One of the classes of buildings included in EPCA is single-family residences. These standards cover the energy used for space heating, air conditioning, and water heating. This report describes the evaluation of direct energy and economic impacts of three proposed levels of single-family BEPS: lenient, mid, and strict. The lenient level is the least stringent in requiring improvements in eneryperformance of residence while the strict is the most stringent. Each of the levels and the method of developing them are also described. The ORNL residential energy model is used to calculate energy savings and economic impacts of BEPS to the nation. The model is also used to estimate the sensitivity of the results to several exogenous variables: projected fuel prices, baseline energy codes, capital csts, short-run price elasticities, and discount rates. The Net Present Value (NPV) and cumulative energy savings from 1980 to 2020 are the two measures used to compare the standards. Both the lenient and mid level standards provide a positive economic benefit to the country of 1.24 and 2.58 billion dollars, respectively. Even though the strict standard has the largest energy savings, it has a negative economic cost of 1.5 billion dollars to the nation. The cumulative energy savings of the lenient, mid, and strict level standards are 4.2, 10.2, and 20.1 EJ, respectively.

  20. Discovering system requirements

    Energy Technology Data Exchange (ETDEWEB)

    Bahill, A.T.; Bentz, B. [Univ. of Arizona, Tucson, AZ (United States). Systems and Industrial Engineering; Dean, F.F. [Sandia National Labs., Albuquerque, NM (United States)

    1996-07-01

    Cost and schedule overruns are often caused by poor requirements that are produced by people who do not understand the requirements process. This report provides a high-level overview of the system requirements process, explaining types, sources, and characteristics of good requirements. System requirements, however, are seldom stated by the customer. Therefore, this report shows ways to help you work with your customer to discover the system requirements. It also explains terminology commonly used in the requirements development field, such as verification, validation, technical performance measures, and the various design reviews.

  1. 40 CFR Table 7 to Subpart IIIi of... - Requirements for Performance Tests for Stationary CI ICE With a Displacement of ≥30 Liters per...

    Science.gov (United States)

    2010-07-01

    ... longer runs. b. Limit the concentration of NOX in the stationary CI internal combustion engine exhaust. i... concentration of PM in the stationary CI internal combustion engine exhaust i. Select the sampling port location... Combustion Engines Part 60, Subpt. IIII, Table 7 Table 7 to Subpart IIII of Part 60—Requirements for...

  2. Strictly Limited Choice or Agency?

    DEFF Research Database (Denmark)

    Nell, Phillip Christopher; Puck, Jonas F.; Heidenreich, Stefan

    2015-01-01

    the external pressures are joined by strong firm-internal pressures. Our findings contribute to the scarce literature on firms’ political strategies in emerging markets. They also support recent criticism of institutional theory’s strong focus on isomorphism as the most important legitimacy-conveying mechanism......This article analyzes political strategies of MNC subsidiaries in emerging markets. We find that institutional pressures from public and private non-market actors in the emerging market lead to increased political activism. Furthermore, we find that these relationships become stronger, when....... We argue that the isomorphism-based either-or logic gives way to stronger agency of the subsidiary and to a logic of active negotiation and social construction of the subsidiary’s legitimacy in the emerging market. Our findings show support for this idea as political activism is one such way how...

  3. Mapping clinical journeys of Asian patients presenting to the Emergency Department with syncope: Strict adoption of international guidelines does not reduce hospitalisations.

    Science.gov (United States)

    Kojodjojo, Pipin; Boey, Elaine; Elangovan, Anita; Chen, Xianyi; Tan, Yuquan; Singh, Devinder; Yeo, Wee Tiong; Lim, Toon Wei; Seow, Swee Chong; Sim, Tiong Beng

    2016-09-01

    Limited data exists about management of syncope in Asia. The American College of Emergency Physicians (ACEP) and European Society of Cardiology (ESC) guidelines have defined the high-risk syncope patient. This study aims to determine the effectiveness of managing syncope in an Asian healthcare system and whether strict adherence of international guidelines would reduce hospitalizations. Patients attending the Emergency Department of a Singaporean tertiary hospital with syncope were identified. Clinical journeys of all patients were meticulously mapped by interrogation of a comprehensive electronic medical record system and linkages with national datasets. Primary endpoint was hospitalization. Secondary endpoints were recurrent syncope within 1year and all-cause mortality. Expected admission rates based on application of ACEP/ESC guidelines were calculated. 638 patients (43.8±22.4years, 49.0% male) presented with syncope. 48.9% were hospitalized for 2.9±3.2days. Yields of common investigations ranged from 0 to 11.5% and no diagnosis was reached in 51.5% of patients. Diuretics use (HR 5.1, p=0.01) and prior hospitalization for syncope (HR 6.9, psyncope. Over 2.8 SD 0.3years of follow-up, 40 deaths occurred. 24 patients who died within 12months of presentation were admitted or had a firm diagnosis upon discharge. Application of guidelines did not significantly reduce hospitalisations, with limited agreement which patients warrant admission. (Actual 376, ACEP 354, ESC 391 admissions, p=NS). Unstructured management of syncope results in nearly half of patients being admitted and substantial healthcare expenditures, yet with limited diagnostic yield. Strict adoption of ACEP or ESC guidelines does not reduce admissions. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  4. Deviation from strict homeostasis across multiple trophic levels in an invertebrate consumer assemblage exposed to high chronic phosphorus enrichment in a Neotropical stream.

    Science.gov (United States)

    Small, Gaston E; Pringle, Catherine M

    2010-03-01

    A central tenet of ecological stoichiometry is that consumer elemental composition is relatively independent of food resource nutrient content. Although the P content of some invertebrate consumer taxa can increase as a consequence of P-enriched food resources, little is known about how ecosystem nutrient loading can affect the elemental composition of entire consumer assemblages. Here we examine the potential for P enrichment across invertebrate consumer assemblages in response to chronic high P loading. We measured elemental ratios in invertebrate consumers and basal food resources in a series of streams in lowland Costa Rica that range widely in P levels (2-135 microg l(-1) soluble reactive P). Streams with high P levels receive natural long-term (over millennia) inputs of solute-rich groundwater while low-P streams do not receive these solute-rich groundwater inputs. P content of leaf litter and epilithon increased fourfold across the natural P gradient, exceeding basal resource P content values reported in the literature from other nutrient-rich streams. Invertebrate consumers from the high-P study stream were elevated twofold in P content across multiple taxonomic and functional feeding groups, including predators. Our results strongly support the hypothesis that elevated P content in consumers feeding on P-enriched food resources is a consequence of deviation from strict homeostasis. In contrast to prior studies, we found that between-stream variation in P content of a given taxon greatly exceeded within-stream variation among different taxa, suggesting that environment may be as important as phylogeny in controlling consumer stoichiometry. Relaxing the assumption of strict homeostasis presents challenges and opportunities for advancing our understanding of how nutrient limitation affects consumer growth. Moreover, our findings may provide a window into the future of how chronic anthropogenic nutrient loading can alter stoichiometric relationships in food

  5. Assessing the Land Subsidence Governance in Ningbo City: By a Close Study of the Building Collapse at the Strictly Protected Land Subsidence Area

    Science.gov (United States)

    Yu, Xia

    2016-04-01

    Ningbo is a coastal city in East China, its land subsidence problem was noticed in the 1960s. However, scientific management was insufficient at that time, so with the fast city development from the 1980s, groundwater was used by a large amount of small factories, and tall buildings were built on the land. It was in 2008, scientists predicted that if without doing anything to prevent the land from subsiding, the city will be covered by the East Sea in 2030. From then on, the local government implied several policies, such as shut down most of the groundwater pumping wells, set up a new authority to enhance the cooperation among different administration departments, and also set up a land subsidence monitoring center for the city. Recently, it is declared that a Stereo regulatory system of land subsidence governance has been achieved. However, in 2012, a 23-years old building in the city center collapsed. According to the City Planning 2009, this building is located just in the strictly protected land subsidence area. The experts, however, think that land subsidence is not the main reason, since there are many illegal changes to the building during the past 23 years. The aim of my research is to assess the land subsidence governance in Ningbo city. I studied the collapsed building, how it was built, what has changed after building, how the environment changed in this area, and how this area became the strictly protected land subsidence area, and what kind of protections have been made. Actually, during the case study I discuss the land subsidence governance design of Ningbo, and to see what practices and lessons we can learn from this case.

  6. Predicting athletic performance with self-confidence and somatic and cognitive anxiety as a function of motor and physiological requirements in six sports.

    Science.gov (United States)

    Taylor, J

    1987-03-01

    The purpose of the present study is to examine the ability of certain psychological attributes to predict performance in six National Collegiate Athletic Association Division I collegiate sports. Eighty-four athletes from the varsity sports teams of cross country running, alpine and nordic skiing, tennis, basketball, and track and field at the University of Colorado completed a questionnaire adapted from Martens (1977; Martens et al., 1983) that measured their trait levels of self-confidence (Bandura, 1977), somatic anxiety, and cognitive anxiety (Martens, 1977; Martens et al., 1983). In addition, at three to six competitions during the season, the members of the cross country running and tennis teams filled out a state measure (Martens et al., 1983) of the three attributes from one to two hours prior to the competition. Following each competition, subjective and objective ratings of performance were obtained, and, for all sports, coaches' ratings of performance and an overall seasonal team ranking were determined as seasonal performance measures. The sports were dichotomized along motor and physiological dimensions. Results indicate that all three psychological attributes were significant predictors of performance in both fine motor, anaerobic sports and gross motor, aerobic sports. Further, clear differences in these relationships emerged as a function of the dichotomization. In addition, unexpected sex differences emerged. The findings are discussed relative to prior research and their implications for future research.

  7. Operating the EOSDIS at the Land Processes DAAC Managing Expectations, Requirements, and Performance Across Agencies, Missions, Instruments, Systems, and User Communities

    Science.gov (United States)

    Kalvelage, Thomas A.

    2002-09-01

    NASA developed the Earth Observing System (EOS) during the 1990's. At the Land Processes Distributed Active Archive Center (LP DAAC), located at the USGS EROS Data Center, the EOS Data and Information System (EOSDIS) is required to support heritage missions as well as Landsat 7, Terra, and Aqua. The original system concept of the early 1990's changed as each community had its say -- first the managers, then engineers, scientists, developers, operators, and then finally the general public. The systems at the LP DAAC -- particularly the largest single system, the EOSDIS Core System (ECS) -- are changing as experience accumulates, technology changes, and each user group gains influence. The LP DAAC has adapted as contingencies were planned for, requirements and therefore plans were modified, and expectations changed faster than requirements could hope to be satisfied. Although not responsible for Quality Assurance of the science data, the LP DAAC works to ensure the data are accessible and useable by influencing systems, capabilities, and data formats where possible, and providing tools and user support as necessary. While supporting multiple missions and instruments, the LP DAAC also works with and learns from multiple management and oversight groups as they review mission requirements, system capabilities, and the overall operation of the LP DAAC. Stakeholders, including the Land Science community, are consulted regularly to ensure that the LP DAAC remains cognizant and responsive to the evolving needs of the user community. Today, the systems do not look or function as originally planned, but they do work, and they allow customers to search and order of an impressive amount of diverse data.

  8. Proposal of requirements for performance in Brazil for systems of external individual monitoring for neutrons applying the TLD-albedo technique

    International Nuclear Information System (INIS)

    Martins, Marcelo M.; Mauricio, Claudia L.P.; Pereira, Walsan W.; Fonseca, Evaldo S. da; Silva, Ademir X.

    2009-01-01

    This work presents a criteria and conditions proposal for the regulations in Brazil of individual monitoring systems for neutrons applying the albedo technique with thermoluminescent detectors. Tests are proposed for the characterization performance of the system based on the Regulation ISO 21909 and on the experience of the authors

  9. Harmine treatment enhances short-term memory in old rats: Dissociation of cognition and the ability to perform the procedural requirements of maze testing.

    Science.gov (United States)

    Mennenga, Sarah E; Gerson, Julia E; Dunckley, Travis; Bimonte-Nelson, Heather A

    2015-01-01

    Harmine is a naturally occurring monoamine oxidase inhibitor that has recently been shown to selectively inhibit the dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A (DYRK1A). We investigated the cognitive effects of 1mg (low) Harmine and 5mg (high) Harmine using the delayed-match-to-sample (DMS) asymmetrical 3-choice water maze task to evaluate spatial working and recent memory, and the Morris water maze task (MM) to test spatial reference memory. Animals were also tested on the visible platform task, a water-escape task with the same motor, motivational, and reinforcement components as the other tasks used to evaluate cognition, but differing in its greater simplicity and that the platform was visible above the surface of the water. A subset of the Harmine-high treated animals showed clear motor impairments on all behavioral tasks, and the visible platform task confirmed a lack of competence to perform the procedural components of water maze testing. After excluding animals from the high dose group that could not perform the procedural components of a swim task, it was revealed that both high- and low-dose treatment with Harmine enhanced performance on the latter portion of DMS testing, but had no effect on MM performance. Thus, this study demonstrates the importance of confirming motor and visual competence when studying animal cognition, and verifies the one-day visible platform task as a reliable measure of ability to perform the procedural components necessary for completion of a swim task. Copyright © 2014. Published by Elsevier Inc.

  10. Dietary threonine requirement of Pekin ducks from 15 to 35 days of age based on performance, yield, serum natural antibodies, and intestinal mucin secretion.

    Science.gov (United States)

    Zhang, Q; Xu, L; Doster, A; Murdoch, R; Cotter, P; Gardner, A; Applegate, T J

    2014-08-01

    A study was conducted to establish the dietary Thr requirement of Pekin ducks from 15 to 35 d of age. Experimental diets were formulated to contain 0.55, 0.60, 0.65, 0.75, and 0.85% Thr (0.57, 0.60, 0.64, 0.72, and 0.80% on an analyzed basis) and were studied in 2 experiments. In experiment 1, each diet was fed to 10 pens of 52 drakes per pen. Samples were collected at d 35 for determinations of carcass yields, serum immune parameters, and intestinal characteristics. Experiment 2 was a digestibility study, wherein 0.5% chromic oxide was mixed into the experimental diets and fed from 15 to 19 d. Ileal digesta were collected at d 19 to analyze mucin secretions and apparent ileal Thr digestibility. The results showed that feeding 0.72% versus 0.64% Thr improved 15 to 35 d BW gain by 55 g (P increased carcass and breast meat yields by 22 and 24 g, respectively. Also, 0.72% Thr had the highest crude mucin secretion on a DM intake (DMI) basis (P increased (P increase. Using nonlinear regressions, Thr requirement was estimated to range from a low of 0.70% to maximize dry crude mucin secretion on a DMI basis to a high of 0.80% to maximize carcass weight and serum IgY production by the linear or quadratic regression. Equivalently, Thr requirement varied between a low of 0.62% to minimize mortality and a high of 0.73% to maximize dry crude mucin secretion expressed as DMI using the quadratic broken-line model. Correspondingly, the apparent ileal digestible Thr requirements were estimated to be 0.52 to 0.66% (0.70 to 0.80% dietary Thr) by quadratic and 0.47 to 0.56% (0.62 to 0.73% dietary Thr) by quadratic broken-line model. © Poultry Science Association Inc.

  11. Performing prototype distortion tasks requires no contribution from the explicit memory systems: evidence from amnesic MCI patients in a new experimental paradigm.

    Science.gov (United States)

    Zannino, Gian Daniele; Perri, Roberta; Zabberoni, Silvia; Caltagirone, Carlo; Marra, Camillo; Carlesimo, Giovanni A

    2012-10-01

    Evidence shows that amnesic patients are able to categorize new exemplars drawn from the same prototype as in previously encountered items. It is still unclear, however, whether this ability is due to a spared implicit learning system or residual explicit memory and/or working memory resources. In this study, we used a new paradigm devised expressly to rule out any possible contribution of episodic and working memory in performing a prototype distortion task. We enrolled patients with amnesic MCI and Normal Controls. Our paradigm consisted of a study phase and a test phase; two-thirds of the participants performed the study phase and all participants performed the test phase. In the study phase, participants had to judge how pleasant morphed faces, drawn from a single prototype, seemed to them. Half of the participants were shown faces drawn from the A-prototype and half from the B-prototype. A- and B-faces were opposite in a morphing space with a neutral human face at the center. In the test phase, participants had to judge the regularity of faces they had never seen before. Three different types of faces were shown in the test phase, that is, A-, B-, or neutral-faces. We expected that implicit learning of the category boundaries would lead to a category-specific increase in perceived regularity. The results confirmed our predictions. In fact, trained subjects (compared with subjects who did not undergo the study phase) assigned higher regularity scores to new faces drawn from the same prototype as the faces seen during training, and they gave lower regularity scores to new faces drawn from the opposite prototype. This effect was super imposable across subjects' groups. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. Health benefit from decreasing exposure to heavy metals and metalloid after strict pollution control measures near a typical river basin area in China.

    Science.gov (United States)

    Cao, Suzhen; Duan, Xiaoli; Ma, Yingqun; Zhao, Xiuge; Qin, Yanwen; Liu, Yan; Li, Sai; Zheng, Binghui; Wei, Fusheng

    2017-10-01

    The metal(loid) pollution still is a great concern due to the effects from urbanization and industrialization. While, the health risks from the toxic metal(loid)s could decrease if strict pollution control measures were adopted. However, few studies to date investigate the health risks of heavy metal(loid)s in a systematic river basin for the dependent residents, after taking pollution control measures. Thus, the contents of metal(loid)s (Cu, Pb, Zn, Cd, Mn, As) in surface water along a typical river basin were investigated in this study, and the potential non-carcinogenic and carcinogenic health risks posed to the residents were assessed. Although the soluble contents of Cu, Pb, Zn and Cd exceeded the respective thresholds in two sites located downstream the mine area, they were greatly decreased in comparison with previous contamination levels, and the soluble concentrations of all the metal(loid)s were within the relevant thresholds in the sites far away from the mining area. Moreover, the closer to the mining area, the higher the pollution levels of metal(loid)s. The total hazard index for non-carcinogenic risks of metal(loid)s were basically lower than the threshold (1) for the local population. Whereas, although the content of metal(loid)s were low (such as As), they could pose relative higher non-carcinogenic health risks. The result illustrated that pollution levels, toxicity of the contaminants and exposure behavior patterns all could contribute to the potential detrimental health risks. Additionally, the non-carcinogenic and carcinogenic risks from ingestion exposure were ∼2-∼4 orders of magnitude higher than those from dermal contact. The total carcinogenic risks were basically lower than the maximum tolerable levels (1.0 × 10 -4 ), indicating carcinogenic risks from most areas of the river could also be accepted. Among different population groups, heavy metal(loid)s posed relative higher non-carcinogenic and carcinogenic risks to the children in

  13. Requirements Engineering

    CERN Document Server

    Hull, Elizabeth; Dick, Jeremy

    2011-01-01

    Written for those who want to develop their knowledge of requirements engineering process, whether practitioners or students.Using the latest research and driven by practical experience from industry, Requirements Engineering gives useful hints to practitioners on how to write and structure requirements. It explains the importance of Systems Engineering and the creation of effective solutions to problems. It describes the underlying representations used in system modeling and introduces the UML2, and considers the relationship between requirements and modeling. Covering a generic multi-layer r

  14. Software requirements

    CERN Document Server

    Wiegers, Karl E

    2003-01-01

    Without formal, verifiable software requirements-and an effective system for managing them-the programs that developers think they've agreed to build often will not be the same products their customers are expecting. In SOFTWARE REQUIREMENTS, Second Edition, requirements engineering authority Karl Wiegers amplifies the best practices presented in his original award-winning text?now a mainstay for anyone participating in the software development process. In this book, you'll discover effective techniques for managing the requirements engineering process all the way through the development cy

  15. Design requirements for ERD in diffusion-dominated media: how do injection interval, bioactive zones and reaction kinetics affect remediation performance?

    DEFF Research Database (Denmark)

    Chambon, Julie Claire Claudia; Lemming, Gitte; Manoli, Gabriele

    groupings (such as the Damkohler number), which combine site specific (physical and biogeochemical) and design parameters, and graphs showing how the main parameters affect remediation timeframes. Finally it is shown how model results can be used as input to other decision making tools such as life cycle...... is to get contact between the injected bacteria and electron donor and the contaminants trapped in the low-permeability matrix. Sampling of intact cores from the low-permeability matrix has shown that the bioactive zones (where degradation occurs) are limited in the matrix, due to the slow diffusion...... transport processes, and this affects the timeframes for the remediation. Due to the limited ERD applications and the complex transport and reactive processes occurring in low-permeability media, design guidelines are currently not available for ERD in such settings, and remediation performance assessments...

  16. When is it acceptable to kill a strictly protected carnivore? Exploring the legal constraints on wildlife management within Europe’s Bern Convention

    Directory of Open Access Journals (Sweden)

    John D. C. Linnell

    2017-09-01

    Full Text Available As wolf populations expand across Europe, many countries face challenges in finding ways to address the concerns of some elements among the rural stakeholders who are being asked to share their landscapes with wolves for the first time in several generations. In these recovery landscapes, wolves are associated with a wide range of conflicts that include economic, psychological, perceptional, social, cultural and political dimensions. A recurring demand concerns the desire to introduce the use of carefully regulated lethal control of wolves, through either culling by state employees or hunting conducted by rural hunters. Introducing such measures can be very controversial, and many critics challenge their legality under the international wildlife conservation instruments that have nurtured wolf recovery. We evaluate this issue for the case of wolves in Norway, which are strictly protected under the Bern Convention. Drawing on the latest results of social science research, we present the multiple lines of argumentation that are often used to justify killing wolves and relate these to the criteria for exceptions that exist under the Bern Convention. We conclude that while the Convention provides apparent scope for allowing the killing of wolves as a means to address conflicts, this must be clearly justified and proportional to the conservation status of wolves so as to not endanger their recovery.

  17. Modeling the adsorption of hydrogen, sodium, chloride and phthalate on goethite using a strict charge-neutral ion-exchange theory

    Science.gov (United States)

    Ndu, Udonna

    2017-01-01

    Simultaneous adsorption modeling of four ions was predicted with a strict net charge-neutral ion-exchange theory and its corresponding equilibrium and mass balance equations. An important key to the success of this approach was the proper collection of all the data, particularly the proton adsorption data, and the inclusion of variable concentrations of conjugate ions from the experimental pH adjustments. Using IExFit software, the ion-exchange model used here predicted the competitive retention of several ions on goethite by assuming that the co-adsorption or desorption of all ions occurred in the correct stoichiometries needed to maintain electroneutrality. This approach also revealed that the retention strength of Cl− ions on goethite increases in the presence of phthalate ions. That is, an anion-anion enhancement effect was observed. The retention of Cl− ions was much weaker than phthalate ions, and this also resulted in a higher sensitivity of the Cl− ions toward minor variations in the surface reactivity. The proposed model uses four goethite surface sites. The drop in retention of phthalate ions at low pH was fully described here as resulting from competitive Cl− reactions, which were introduced in increasing concentrations into the matrix as the conjugate base to the acid added to lower the pH. PMID:28464020

  18. Przewalski’ s Horse ( Equus ferus przewalskii Re-intr oduction in the Great Gobi B Strictly Protected Area: from Species to Ecosystem Conservation

    Directory of Open Access Journals (Sweden)

    P. Kaczensky

    2007-05-01

    Full Text Available The Przewalski’s horse ( Equus ferus przewalskii Po ljakov , 1881, or “T akhi” in Mongolian, became extinct in the wild by the mid 1960’ s. The last recorded sightings of Przewalski’s horses occurred in the Dzungarian Gobi desert in SW Mo ngolia, today’s Great Gobi B Strictly Protected Area (SP A. A re - introduction program was initiated in 1992 and the fi rs t group of captive-born Przewalski’s horses was airlifted to the SPA. Given the logistical challenges associated with such a venture, the initial project focus has been on transport logistics and the well-being of the re-introduced horses. Tod ay, conservation efforts are spread over the entire protected area. Present day ef forts include other mammals, vegetation and the local people. Due to its important symbolic value in Mongolian culture, the Przewalski’ s horse became an important fl agship species for the protected area’s conservation and management.

  19. Asymmetric reduction of ketopantolactone using a strictly (R)-stereoselective carbonyl reductase through efficient NADPH regeneration and the substrate constant-feeding strategy.

    Science.gov (United States)

    Zhao, Man; Gao, Liang; Zhang, Li; Bai, Yanbin; Chen, Liang; Yu, Meilan; Cheng, Feng; Sun, Jie; Wang, Zhao; Ying, Xiangxian

    2017-11-01

    To characterize a recombinant carbonyl reductase from Saccharomyces cerevisiae (SceCPR1) and explore its use in asymmetric synthesis of (R)-pantolactone [(R)-PL]. The NADPH-dependent SceCPR1 exhibited strict (R)-enantioselectivity and high activity in the asymmetric reduction of ketopantolactone (KPL) to (R)-PL. Escherichia coli, coexpressing SceCPR1 and glucose dehydrogenase from Exiguobacterium sibiricum (EsGDH), was constructed to fulfill efficient NADPH regeneration. During the whole-cell catalyzed asymmetric reduction of KPL, the spontaneous hydrolysis of KPL significantly affected the yield of (R)-PL, which was effectively alleviated by the employment of the substrate constant-feeding strategy. The established whole-cell bioreduction for 6 h afforded 458 mM (R)-PL with the enantiomeric excess value of >99.9% and the yield of 91.6%. Escherichia coli coexpressing SceCPR1 and EsGDH efficiently catalyzed the asymmetric synthesis of (R)-PL through the substrate constant-feeding strategy.

  20. Requirement of n-6 and n-3 Fatty Acid in Broodstock Diets on Reproductive Performance of Green catfish, Hemibagrus nemurus Blkr.

    Directory of Open Access Journals (Sweden)

    Adharto Utiah

    2007-01-01

    Full Text Available This experiment was conducted to determine the optimum dietary level of n-6 and n-3 fatty acids on reproduction performance of green catfish. Four experimental diets with different level of n-6 and n-3 fatty acid (diet A: 0.77% n-6 fatty acid, 0.07% n-3 fatty acid; diet B: 1.56%,0.10 %; diet C: 1.74%, 0.13 % and diet D: 2%, 0.28% were used in this experiment during seven month. Diets given twice every day in the morning and evening. The 28 broodstock used in this research with density every waring seven broodstock. Samples of eggs were analyzed for fatty acid composition. The diameter of eggs, fecundity, hatching rate of the eggs, survival rate and percentage of abnormal larvae were determined. Results showed that different dietary level of n-6 and n-3 fatty acids of the broodstock significantly affect the reproductive performance especially fecundity and hatching rate of eggs. The maximum fecundity, egg diameter, and hatching rate were produced broodstock fed on 1.56% n-6 fatty acid and 0.10 % n-3 fatty acid in diet by at the level of 12.29% lipid. Keywords : n-6 and n-3 fatty acids, reproduction performance, green catfish, Hemibagrus nemurus.   Abstrak Penelitian ini dilakukan pada berbagai level asam lemak n-6 dan n-3 dalam pakan untuk melihat pengaruhnya terhadap penampilan reproduksi dari ikan baung. Penelitian dilaksanakan selama 7 bulan.  Empat jenis pakan  digunakan dalam percobaan ini dengan perbedaan kandungan asam lemak n-6 dan n-3 (pakan A: 0,77% asam lemak n-6, 0,56% asam lemak n-3; pakan B: 1,56%, 0,78%; pakan C: 1,74%, 1,00% and pakan D: 2,03%, 1,82%. Dalam penelitian ini 28 ekor induk digunakan dan ditebarkan kedalam waring dengan kepadatan 7 ekor tiap waring. Pakan diberikan pagi dan sore hari secara at satiation.  Sampel telur dan larva dianalisa komposisi asam lemak. Penampilan reproduksi yang diamati adalah diameter telur, fekunditas, derajat penetasan telur, derajat kelangsungan hidup larva dan persentase larva abnormal

  1. A review of horticultural export performance of Asian developing countries: aspects of quality, competitiveness and sustainability.

    NARCIS (Netherlands)

    Jansen, H.G.P.

    1994-01-01

    Many developing countries in Asia have a comparative advantage in the production of horticultural commodities. Drawing from the widely diverging experiences of six countries, it is concluded that government policies significantly influence horticultural export performance. In order to meet strict

  2. Recurrent fuzzy neural network backstepping control for the prescribed output tracking performance of nonlinear dynamic systems.

    Science.gov (United States)

    Han, Seong-Ik; Lee, Jang-Myung

    2014-01-01

    This paper proposes a backstepping control system that uses a tracking error constraint and recurrent fuzzy neural networks (RFNNs) to achieve a prescribed tracking performance for a strict-feedback nonlinear dynamic system. A new constraint variable was defined to generate the virtual control that forces the tracking error to fall within prescribed boundaries. An adaptive RFNN was also used to obtain the required improvement on the approximation performances in order to avoid calculating the explosive number of terms generated by the recursive steps of traditional backstepping control. The boundedness and convergence of the closed-loop system was confirmed based on the Lyapunov stability theory. The prescribed performance of the proposed control scheme was validated by using it to control the prescribed error of a nonlinear system and a robot manipulator. © 2013 ISA. Published by Elsevier Ltd. All rights reserved.

  3. Transportation System Requirements Document

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    This Transportation System Requirements Document (Trans-SRD) describes the functions to be performed by and the technical requirements for the Transportation System to transport spent nuclear fuel (SNF) and high-level radioactive waste (HLW) from Purchaser and Producer sites to a Civilian Radioactive Waste Management System (CRWMS) site, and between CRWMS sites. The purpose of this document is to define the system-level requirements for Transportation consistent with the CRWMS Requirement Document (CRD). These requirements include design and operations requirements to the extent they impact on the development of the physical segments of Transportation. The document also presents an overall description of Transportation, its functions, its segments, and the requirements allocated to the segments and the system-level interfaces with Transportation. The interface identification and description are published in the CRWMS Interface Specification.

  4. Hepatitis A in Puglia (South Italy) after 10 years of universal vaccination: need for strict monitoring and catch-up vaccination

    Science.gov (United States)

    2012-01-01

    Background Raw seafood consumption was identified as the major risk factor for hepatitis A during the large epidemic of 1996 and 1997 in Puglia (South Italy). In Puglia, vaccination for toddlers and preadolescents has been recommended since 1998. The aim of the study was to evaluate the incidence, seroprevalence, molecular epidemiology, and environmental circulation of hepatitis A virus (HAV) in Puglia more than ten years after the introduction of anti-HAV vaccination in the regional immunization program. Methods Data on the incidence of acute hepatitis A in Puglia were analyzed. Characteristics and risk factors of 97 acute hepatitis A cases occurring in 2008–2009 were analyzed. Serum samples from 868 individuals aged 0 to 40 years were tested for anti-HAV antibodies. Fecal samples from 49 hepatitis A cases were analyzed by sequence analysis in the VP1/P2A region. In 2008, 203 mussel samples and 202 water samples from artesian wells were tested for HAV-RNA. Results Between 1998 and 2009, the incidence of acute hepatitis A declined from 14.8 to 0.8 per 100,000. The most frequent risk factors reported by cases in 2008–2009 were shellfish consumption (85%) and travel outside of Puglia or Italy (26%). Seroepidemiologic survey revealed high susceptibility to HAV in children and adults up to age 30 (65%-70%). None of the mussel or water samples were HAV-positive. Phylogenetic analysis revealed co-circulation of subtypes IA (74%) and IB (26%) and clustering of strains with strains from Germany and France, and those previously circulating in Puglia. Conclusion Vaccination and improved sanitation reduced the incidence of hepatitis A. Strict monitoring and improved vaccination coverage are needed to prevent disease resurgence. PMID:23098290

  5. Altered Na+ transport after an intracellular alpha-subunit deletion reveals strict external sequential release of Na+ from the Na/K pump.

    Science.gov (United States)

    Yaragatupalli, Siddhartha; Olivera, J Fernando; Gatto, Craig; Artigas, Pablo

    2009-09-08

    The Na/K pump actively exports 3 Na(+) in exchange for 2 K(+) across the plasmalemma of animal cells. As in other P-type ATPases, pump function is more effective when the relative affinity for transported ions is altered as the ion binding sites alternate between opposite sides of the membrane. Deletion of the five C-terminal residues from the alpha-subunit diminishes internal Na(+) (Na(i)(+)) affinity approximately 25-fold [Morth et al. (2007) Nature 450:1043-1049]. Because external Na(+) (Na(o)(+)) binding is voltage-dependent, we studied the reactions involving this process by using two-electrode and inside-out patch voltage clamp in normal and truncated (DeltaKESYY) Xenopus-alpha1 pumps expressed in oocytes. We observed that DeltaKESYY (i) decreased both Na(o)(+) and Na(i)(+) apparent affinities in the absence of K(o)(+), and (ii) did not affect apparent Na(o)(+) affinity at high K(o)(+). These results support a model of strict sequential external release of Na(+) ions, where the Na(+)-exclusive site releases Na(+) before the sites shared with K(+) and the DeltaKESYY deletion only reduces Na(o)(+) affinity at the shared sites. Moreover, at nonsaturating K(o)(+), DeltaKESYY induced an inward flow of Na(+) through Na/K pumps at negative potentials. Guanidinium(+) can also permeate truncated pumps, whereas N-methyl-D-glucamine cannot. Because guanidinium(o)(+) can also traverse normal Na/K pumps in the absence of both Na(o)(+) and K(o)(+) and can also inhibit Na/K pump currents in a Na(+)-like voltage-dependent manner, we conclude that the normal pathway transited by the first externally released Na(+) is large enough to accommodate guanidinium(+).

  6. Lebetimonas natsushimae sp. nov., a novel strictly anaerobic, moderately thermophilic chemoautotroph isolated from a deep-sea hydrothermal vent polychaete nest in the Mid-Okinawa Trough.

    Science.gov (United States)

    Nagata, Ryousuke; Takaki, Yoshihiro; Tame, Akihiro; Nunoura, Takuro; Muto, Hisashi; Mino, Sayaka; Sawayama, Shigeki; Takai, Ken; Nakagawa, Satoshi

    2017-09-01

    A moderately thermophilic, strictly anaerobic, chemoautotrophic bacterium, designated strain HS1857 T , was isolated from a deep-sea hydrothermal vent at the Noho site in the Mid-Okinawa Trough. Strain HS1857 T grew between 35 and 63°C (optimum 55°C), in the presence of 10-55gl -1 NaCl (optimum 25gl -1 ), and pH 5.5-7.1 (optimum 6.4). Growth occurred with molecular hydrogen as the electron donor and elemental sulfur, nitrate, or selenate as the electron acceptors. Formate could serve as an alternative electron donor with nitrate as an electron acceptor. During growth with nitrate as the electron acceptor, strain HS1857 T produced ammonium and formed a biofilm. CO 2 was utilized as the sole carbon source. The G+C content of the genomic DNA was 33.2mol%. Phylogenetic analysis of the 16S rRNA gene sequence indicated that strain HS1857 T is a member of the order Nautiliales, showing a sequence similarity of 95.0% with Lebetimonas acidiphila Pd55 T . The fatty acid composition was similar to that of L. acidiphila, which was dominated by C 18:0 (47.0%) and C 18:1 (23.7%). Based on the genomic, chemotaxonomic, phenotypic characteristics, the name Lebetimonas natsushimae sp. nov., is proposed. The type strain is HS1857 T (=NBRC 112478 T =DSM 104102 T ). Copyright © 2017 Elsevier GmbH. All rights reserved.

  7. Modality-dependent dose requirements in the Austrian breast cancer early detection program. First results from technical quality assurance; Geraeteabhaengiger Dosisbedarf im Oesterreichischen Brustkrebsfrueherkennungsprogramm. Erste Ergebnisse aus der technischen Qualitaetssicherung

    Energy Technology Data Exchange (ETDEWEB)

    Osanna-Elliott, A.; Semturs, F.; Menhart, S.; Schloegl, C.; Wildner, S.; Zwettler, G. [AGES, Wien (Austria). Referenzzentrum fuer technische Qualitaetssicherung im Brustkrebsfrueherkennungsprogramm

    2015-07-01

    The Austrian Breast Cancer Early Detection Program (BKFP) has officially started in January 2014. In order to ensure that all participating women can rely on a sufficient cancer detection rate while at the same time the required dose is as low as reasonably achievable, all participating radiology institutes (approx. 200) have to fulfill strict quality assurance requirements. The control and certification is performed by the Reference Center for Technical Quality Assurance (RefZQS), which has been developing the methods and tolerances in a pilot project since 2007. The limits are defined in the EUREF-Oeprotocol which is based on the European EPQC guidelines. From the requirement for optimized image quality while simultaneously following the ALARA principle, we found modality-dependent dose requirements, which we had expected but which have now been compiled for the first time for Austria.

  8. Closure requirements

    International Nuclear Information System (INIS)

    Hutchinson, I.P.G.; Ellison, R.D.

    1992-01-01

    Closure of a waste management unit can be either permanent or temporary. Permanent closure may be due to: economic factors which make it uneconomical to mine the remaining minerals; depletion of mineral resources; physical site constraints that preclude further mining and beneficiation; environmental, regulatory or other requirements that make it uneconomical to continue to develop the resources. Temporary closure can occur for a period of several months to several years, and may be caused by factors such as: periods of high rainfall or snowfall which prevent mining and waste disposal; economic circumstances which temporarily make it uneconomical to mine the target mineral; labor problems requiring a cessation of operations for a period of time; construction activities that are required to upgrade project components such as the process facilities and waste management units; and mine or process plant failures that require extensive repairs. Permanent closure of a mine waste management unit involves the provision of durable surface containment features to protect the waters of the State in the long-term. Temporary closure may involve activities that range from ongoing maintenance of the existing facilities to the installation of several permanent closure features in order to reduce ongoing maintenance. This paper deals with the permanent closure features

  9. Congestion Management Requirements, Methods and Performance Indices

    Energy Technology Data Exchange (ETDEWEB)

    Kirby, B.J.

    2002-08-28

    Transmission congestion occurs when there is insufficient transmission capacity to simultaneously accommodate all requests for transmission service within a region. Historically, vertically integrated utilities managed this condition by constraining the economic dispatch of generators with the objective of ensuring security and reliability of their own and/or neighboring systems. Electric power industry restructuring has moved generation investment and operations decisions into the competitive market but has left transmission as a communal resource in the regulated environment. This mixing of competitive generation and regulated transmission makes congestion management difficult. The difficulty is compounded by increases in the amount of congestion resulting from increased commercial transactions and the relative decline in the amount of transmission. Transmission capacity, relative to peak load, has been declining in all regions of the U.S. for over a decade. This decline is expected to continue. Congestion management schemes used today have negative impacts on energy markets, such as disruptions and monetary penalties, under some conditions. To mitigate these concerns various congestion management methods have been proposed, including redispatch and curtailment of scheduled energy transmission. In the restructured electric energy industry environment, new congestion management approaches are being developed that strive to achieve the desired degree of reliability while supporting competition in the bulk power market. This report first presents an overview and background on key issues and emerging approaches to congestion management. It goes on to identify and describe policies affecting congestion management that are favored and/or are now being considered by FERC, NERC, and one of the regional reliability councils (WSCC). It reviews the operational procedures in use or proposed by three of the leading independent system operators (ISOs) including ERCOT, California ISO, and PJM. Finally, it presents recommendations for evaluating the competing alternative approaches and developing metrics to use in such evaluations. As with any report concerning electricity restructuring, specific details quickly become dated. Individual utilities, states and regions will inevitably change rules and procedures even during the time it takes to publish a report. Hopefully, the general conclusions are more robust and this report will continue to have value even after some of the specific details have changed.

  10. Double Arm Linkage precision Linear motion (DALL) Carriage, a simplified, rugged, high performance linear motion stage for the moving mirror of an Fourier Transform Spectrometer or other system requiring precision linear motion

    Science.gov (United States)

    Johnson, Kendall B.; Hopkins, Greg

    2017-08-01

    The Double Arm Linkage precision Linear motion (DALL) carriage has been developed as a simplified, rugged, high performance linear motion stage. Initially conceived as a moving mirror stage for the moving mirror of a Fourier Transform Spectrometer (FTS), it is applicable to any system requiring high performance linear motion. It is based on rigid double arm linkages connecting a base to a moving carriage through flexures. It is a monolithic design. The system is fabricated from one piece of material including the flexural elements, using high precision machining. The monolithic design has many advantages. There are no joints to slip or creep and there are no CTE (coefficient of thermal expansion) issues. This provides a stable, robust design, both mechanically and thermally and is expected to provide a wide operating temperature range, including cryogenic temperatures, and high tolerance to vibration and shock. Furthermore, it provides simplicity and ease of implementation, as there is no assembly or alignment of the mechanism. It comes out of the machining operation aligned and there are no adjustments. A prototype has been fabricated and tested, showing superb shear performance and very promising tilt performance. This makes it applicable to both corner cube and flat mirror FTS systems respectively.

  11. Grant Closeout Requirements and Reports

    Science.gov (United States)

    Requirements and reports to comply with grant closeout, including Final Federal Financial Report (FFR, SF425); Final Research Performance Progress Report (FRPPR); Interim Research Performance Progress Report (IRPPR); Final Invention Statement (FIS, HHS

  12. Leakage Performance of the GM + CCL Liner System for the MSW Landfill

    Directory of Open Access Journals (Sweden)

    Fan Jingjing

    2014-01-01

    Full Text Available The contaminants in the landfill leachate press pose a grave threat to environment of the soil and the groundwater beneath the landfill. Despite there being strict requirements in relevant provisions of both domestic and foreign countries for the design of the bottom liner system. Pollution of the soil and the groundwater still took place in a number of landfills because of the leakage. To investigate the leakage rate of the liner systems, the minimum design requirements of the liner systems are summarized according to the provisions of four countries, including China, USA, Germany, and Japan. Comparative analyses using one-dimensional transport model are conducted to study the leakage performance of these liner systems composed of geomembrance (GM and compacted clay layer (CCL meeting the relevant minimum design requirements. Then parametric analyses are conducted to study the effects of the hydraulic head, the thickness of GM, the hydraulic conductivity of CCL, and so forth on the leakage performance of the liner system. It is concluded that the liner system designed according to the minimum design requirements of Germany provide the best antileakage performance, while that of Japan performs the lowest. The key parameters affecting the failure time of the liner system are summarized. Finally, some suggestions for the design of the liner systems are made according to the analyses.

  13. Development and performances of a high statistics PMT test facility

    Directory of Open Access Journals (Sweden)

    Mollo Carlos Maximiliano

    2016-01-01

    Full Text Available Since almost a century photomultipliers have been the main sensors for photon detection in nuclear and astro-particle physics experiments. In recent years the search for cosmic neutrinos gave birth to enormous size experiments (Antares, Kamiokande, Super-Kamiokande, etc. and even kilometric scale experiments as ICECUBE and the future KM3NeT. A very large volume neutrino telescope like KM3NeT requires several hundreds of thousands photomultipliers. The performance of the telescope strictly depends on the performance of each PMT. For this reason, it is mandatory to measure the characteristics of each single sensor. The characterization of a PMT normally requires more than 8 hours mostly due to the darkening step. This means that it is not feasible to measure the parameters of each PMT of a neutrino telescope without a system able to test more than one PMT simultaneously. For this application, we have designed, developed and realized a system able to measure the main characteristics of 62 3-inch photomultipliers simultaneously. Two measurement sessions per day are possible. In this work, we describe the design constraints and how they have been satisfied. Finally, we show the performance of the system and the first results coming from the test of few thousand tested PMTs.

  14. Quality assurance requirements in the testing of packages to be used for safe transportation of RAM

    International Nuclear Information System (INIS)

    Vieru, Gheorghe; Nistor, Viorica; Mihaiu, Ramona

    2010-01-01

    The quality of the Type A, B or C packages used for transport and storage of Radioactive Material (RAM) has to be proved by performing qualification tests in accordance with the Transport Regulations, within the Reliability and Testing Laboratory, Institute for Nuclear Research (INR) Pitesti, where has designed and developed a new Romanian Testing Facility. The qualifications testing are performed under a strict quality assurance programme based on the specific procedures prior approved by the Romanian Nuclear Regulatory Body CNCAN (National Commission for Nuclear Activity Control). This paper describe the quality assurance programme in accordance with the quality management system developed in order to meet the requirements provided by the national regulations as well as to the requirements of the IAEA's safety standard TS-R-1 related to testing of packages to be used for transport of RAM and also provides an overview of the new Romanian Testing Facilities for RAM Packages, developed by the INR's Reliability and Testing Laboratory within an Excellence Scientific Contract. (authors)

  15. Effect of residual elements on high performance nickel base ...

    Indian Academy of Sciences (India)

    Unknown

    temperature properties coupled with corrosion resistance, have been widely used as gas turbine engine components. The physical metallurgy of superalloys demands the highest degree of process consistency and reproducibility, requiring melters of these alloys to exercise strict control and discipline during manufacture.

  16. Effect of residual elements on high performance nickel base ...

    Indian Academy of Sciences (India)

    Unknown

    highest degree of process consistency and reproducibility, requiring melters of these alloys to exercise strict control and discipline during manufacture. The need for improved gas turbine operating efficiency .... end of melt in order to desulphurize the bath. Otherwise,. 'sulphur' is mainly controlled through judicious selection.

  17. A Conserved GPG-Motif in the HIV-1 Nef Core Is Required for Principal Nef-Activities.

    Directory of Open Access Journals (Sweden)

    Marta Martínez-Bonet

    Full Text Available To find out new determinants required for Nef activity we performed a functional alanine scanning analysis along a discrete but highly conserved region at the core of HIV-1 Nef. We identified the GPG-motif, located at the 121-137 region of HIV-1 NL4.3 Nef, as a novel protein signature strictly required for the p56Lck dependent Nef-induced CD4-downregulation in T-cells. Since the Nef-GPG motif was dispensable for CD4-downregulation in HeLa-CD4 cells, Nef/AP-1 interaction and Nef-dependent effects on Tf-R trafficking, the observed effects on CD4 downregulation cannot be attributed to structure constraints or to alterations on general protein trafficking. Besides, we found that the GPG-motif was also required for Nef-dependent inhibition of ring actin re-organization upon TCR triggering and MHCI downregulation, suggesting that the GPG-motif could actively cooperate with the Nef PxxP motif for these HIV-1 Nef-related effects. Finally, we observed that the Nef-GPG motif was required for optimal infectivity of those viruses produced in T-cells. According to these findings, we propose the conserved GPG-motif in HIV-1 Nef as functional region required for HIV-1 infectivity and therefore with a potential interest for the interference of Nef activity during HIV-1 infection.

  18. Performance Characterization of UV Science Cameras Developed for the Chromospheric Lyman-Alpha Spectro-Polarimeter

    Science.gov (United States)

    Champey, P.; Kobayashi, K.; Winebarger, A.; Cirtain, J.; Hyde, D.; Robertson, B.; Beabout, D.; Beabout, B.; Stewart, M.

    2014-01-01

    The NASA Marshall Space Flight Center (MSFC) has developed a science camera suitable for sub-orbital missions for observations in the UV, EUV and soft X-ray. Six cameras will be built and tested for flight with the Chromospheric Lyman-Alpha Spectro-Polarimeter (CLASP), a joint National Astronomical Observatory of Japan (NAOJ) and MSFC sounding rocket mission. The goal of the CLASP mission is to observe the scattering polarization in Lyman-alpha and to detect the Hanle effect in the line core. Due to the nature of Lyman-alpha polarization in the chromosphere, strict measurement sensitivity requirements are imposed on the CLASP polarimeter and spectrograph systems; science requirements for polarization measurements of Q/I and U/I are 0.1 percent in the line core. CLASP is a dual-beam spectro-polarimeter, which uses a continuously rotating waveplate as a polarization modulator, while the waveplate motor driver outputs trigger pulses to synchronize the exposures. The CCDs are operated in frame-transfer mode; the trigger pulse initiates the frame transfer, effectively ending the ongoing exposure and starting the next. The strict requirement of 0.1 percent polarization accuracy is met by using frame-transfer cameras to maximize the duty cycle in order to minimize photon noise. Coating the e2v CCD57-10 512x512 detectors with Lumogen-E coating allows for a relatively high (30 percent) quantum efficiency at the Lyman-alpha line. The CLASP cameras were designed to operate with 10 e-/pixel/second dark current, 25 e- read noise, a gain of 2.0 +/- 0.5 and 1.0 percent residual non-linearity. We present the results of the performance characterization study performed on the CLASP prototype camera; dark current, read noise, camera gain and residual non-linearity.

  19. Requirement for digestible calcium by eleven- to twenty-five-kilogram pigs as determined by growth performance, bone ash concentration, calcium and phosphorus balances, and expression of genes involved in transport of calcium in intestinal and kidney cells.

    Science.gov (United States)

    González-Vega, J C; Liu, Y; McCann, J C; Walk, C L; Loor, J J; Stein, H H

    2016-08-01

    Two experiments were conducted to determine the requirement for standardized total tract digestible (STTD) Ca by 11- to 25-kg pigs based on growth performance, bone ash, or Ca and P retention and to determine the effect of dietary Ca on expression of genes related to Ca transport in the jejunum and kidneys. Six diets were formulated to contain 0.36% STTD P and 0.32, 0.40, 0.48, 0.56, 0.64, or 0.72% STTD Ca by including increasing quantities of calcium carbonate in the diets at the expense of cornstarch. Two additional diets contained 0.72% STTD Ca and 0.33% or 0.40% STTD P to determine if 0.36% STTD P had negative effects on the Ca requirement. The same batch of all diets was used in both experiments. In Exp. 1, 256 pigs (11.39 ± 1.21 kg initial BW) were randomly allotted to the 8 diets with 4 pigs per pen and 8 replicate pens per diet in a randomized complete block design. On the last day of the experiment, 1 pig from each pen was euthanized and the right femur and intestine and kidney samples were collected. Results indicated that ADG and G:F started to decline (linear and quadratic, urine samples were collected using the marker-to-marker approach. Results indicated that the requirement for STTD Ca to maximize Ca and P retention (g/d) was 0.60 and 0.49%, respectively. In conclusion, the STTD Ca requirement by 11- to 25-kg pigs to maximize bone ash was 0.48%; however, ADG and G:F declined if more than 0.54 or 0.50% STTD Ca, respectively, was fed, and the minimum concentration of Ca needed to maximize ADG and G:F could not be determined under the conditions of this experiment. Increasing dietary Ca decreased the mRNA expression of several genes related to transcellular Ca transport in the jejunum and the kidneys.

  20. Implementation of Statistical Process Control: Evaluating the Mechanical Performance of a Candidate Silicone Elastomer Docking Seal

    Science.gov (United States)

    Oravec, Heather Ann; Daniels, Christopher C.

    2014-01-01

    The National Aeronautics and Space Administration has been developing a novel docking system to meet the requirements of future exploration missions to low-Earth orbit and beyond. A dynamic gas pressure seal is located at the main interface between the active and passive mating components of the new docking system. This seal is designed to operate in the harsh space environment, but is also to perform within strict loading requirements while maintaining an acceptable level of leak rate. In this study, a candidate silicone elastomer seal was designed, and multiple subscale test articles were manufactured for evaluation purposes. The force required to fully compress each test article at room temperature was quantified and found to be below the maximum allowable load for the docking system. However, a significant amount of scatter was observed in the test results. Due to the stochastic nature of the mechanical performance of this candidate docking seal, a statistical process control technique was implemented to isolate unusual compression behavior from typical mechanical performance. The results of this statistical analysis indicated a lack of process control, suggesting a variation in the manufacturing phase of the process. Further investigation revealed that changes in the manufacturing molding process had occurred which may have influenced the mechanical performance of the seal. This knowledge improves the chance of this and future space seals to satisfy or exceed design specifications.

  1. Rasp21 sequences opposite the nucleotide binding pocket are required for GRF-mediated nucleotide release

    DEFF Research Database (Denmark)

    Leonardsen, L; DeClue, J E; Lybaek, H

    1996-01-01

    The substrate requirements for the catalytic activity of the mouse Cdc25 homolog Guanine nucleotide Release Factor, GRF, were determined using the catalytic domain of GRF expressed in insect cells and E. coli expressed H-Ras mutants. We found a requirement for the loop 7 residues in Ras (amino ac...... and the human Ras like proteins RhoA, Rap1A, Rac1 and G25K revealed a strict Ras specificity; of these only S. pombe Ras was GRF sensitive....

  2. Utility requirements for fusion

    International Nuclear Information System (INIS)

    Vondrasek, R.J.

    1982-02-01

    This report describes work done and results obtained during performance of Task 1 of a study of Utility Requirements and Criteria for Fusion Options. The work consisted of developing a list of utility requirements for fusion optics containing definition of the requirements and showing their relative importance to the utility industry. The project team members developed a preliminary list which was refined by discussions and literature searches. The refined list was recast as a questionnaire which was sent to a substantial portion of the utility industry in this country. Forty-three questionnaire recipients responded including thirty-two utilities. A workshop was held to develop a revised requirements list using the survey responses as a major input. The list prepared by the workshop was further refined by a panel consisting of vice presidents of the three project team firms. The results of the study indicate that in addition to considering the cost of energy for a power plant, utilities consider twenty-three other requirements. Four of the requirements were judged to be vital to plant acceptability: Plant Capital Cost, Financial Liability, Plant Safety and Licensability

  3. Requirement Assurance: A Verification Process

    Science.gov (United States)

    Alexander, Michael G.

    2011-01-01

    Requirement Assurance is an act of requirement verification which assures the stakeholder or customer that a product requirement has produced its "as realized product" and has been verified with conclusive evidence. Product requirement verification answers the question, "did the product meet the stated specification, performance, or design documentation?". In order to ensure the system was built correctly, the practicing system engineer must verify each product requirement using verification methods of inspection, analysis, demonstration, or test. The products of these methods are the "verification artifacts" or "closure artifacts" which are the objective evidence needed to prove the product requirements meet the verification success criteria. Institutional direction is given to the System Engineer in NPR 7123.1A NASA Systems Engineering Processes and Requirements with regards to the requirement verification process. In response, the verification methodology offered in this report meets both the institutional process and requirement verification best practices.

  4. Utility requirements for HTGRs

    International Nuclear Information System (INIS)

    Nicholls, D.R.

    1997-01-01

    Eskom, the state utility of South Africa, is currently evaluating the technical and economic feasibility of the helium cooled Pebble Bed Modular Reactor with a closed cycle gas turbine power conversion system for future power generating additions to its electric system. This paper provides an overview of the Eskom system including the needs of the utility for future generation capacity and the key performance requirements necessary for incorporation of this gas cooled reactor plant. (author)

  5. Comments on the thesis of Schopenhauer's psicology: "The strict distincttion between knowledge and will and the priority of the first one" from Complementos ao mundo como vontade e representação

    Directory of Open Access Journals (Sweden)

    André Luiz Simões Pedreira

    2015-04-01

    Full Text Available Our paper aims to review the theories of the psychology of Schopenhauer, namely, "strict distinction between will and knowledge and the primacy of the first", contained in the Book Room ons of The World as Will and Representation, in Chapter 41, entitled "on Death and its relationship with the indestructible character of our being itself." The review aimed to present some of the passages ons that ensure the distinction between Will and Intellect in order to provide data to avoid confusion, that many readers Schopenhauer are affected, the Will to confuse metaphysics with its phenomenon, namely the human will.

  6. Waste management system requirements document

    International Nuclear Information System (INIS)

    1991-02-01

    This volume defines the top level requirements for the Mined Geologic Disposal System (MGDS). It is designed to be used in conjunction with Volume 1 of the WMSR, General System Requirements. It provides a functional description expanding the requirements allocated to the MGDS in Volume 1 and elaborates on each requirement by providing associated performance criteria as appropriate. Volumes 1 and 4 of the WMSR provide a minimum set of requirements that must be satisfied by the final MGDS design. This document sets forth specific requirements that must be fulfilled. It is not the intent or purpose of this top level document to describe how each requirement is to be satisfied in the final MGDS design. Each subsequent level of the technical document hierarchy must provide further guidance and definition as to how each of these requirements is to be implemented in the design. It is expected that each subsequent level of requirements will be significantly more detailed. Section 2 of this volume provides a functional description of the MGDS. Each function is addressed in terms of requirements, and performance criteria. Section 3 provides a list of controlling documents. Each document cited in a requirement of Chapter 2 is included in this list and is incorporated into this document as a requirement on the final system. The WMSR addresses only federal requirements (i.e., laws, regulations and DOE orders). State and local requirements are not addressed. However, it will be specifically noted at the potentially affected WMSR requirements that there could be additional or more stringent regulations imposed by a state or local requirements or administering agency over the cited federal requirements

  7. What is 3D good for? A review of human performance on stereoscopic 3D displays

    Science.gov (United States)

    McIntire, John P.; Havig, Paul R.; Geiselman, Eric E.

    2012-06-01

    This work reviews the human factors-related literature on the task performance implications of stereoscopic 3D displays, in order to point out the specific performance benefits (or lack thereof) one might reasonably expect to observe when utilizing these displays. What exactly is 3D good for? Relative to traditional 2D displays, stereoscopic displays have been shown to enhance performance on a variety of depth-related tasks. These tasks include judging absolute and relative distances, finding and identifying objects (by breaking camouflage and eliciting perceptual "pop-out"), performing spatial manipulations of objects (object positioning, orienting, and tracking), and navigating. More cognitively, stereoscopic displays can improve the spatial understanding of 3D scenes or objects, improve memory/recall of scenes or objects, and improve learning of spatial relationships and environments. However, for tasks that are relatively simple, that do not strictly require depth information for good performance, where other strong cues to depth can be utilized, or for depth tasks that lie outside the effective viewing volume of the display, the purported performance benefits of 3D may be small or altogether absent. Stereoscopic 3D displays come with a host of unique human factors problems including the simulator-sickness-type symptoms of eyestrain, headache, fatigue, disorientation, nausea, and malaise, which appear to effect large numbers of viewers (perhaps as many as 25% to 50% of the general population). Thus, 3D technology should be wielded delicately and applied carefully; and perhaps used only as is necessary to ensure good performance.

  8. SDC detector foundation requirements

    International Nuclear Information System (INIS)

    Western, J.L.; Butalla, M.W.

    1992-01-01

    The Solenoidal Detector Collaboration (SDC) Detector weighs approximately 32,000 metric tons, and its ability to perform to design specifications is directly related to its internal alignment. The limits of the misalignment tolerance envelope in combination with the detector weight impose a set of tolerance limits of performance directly upon the foundation structure. The foundation must accommodate different detector loading conditions during installation, operation, maintenance, and future enhancements. The foundation must also respond to the loading conditions within a restrictive set of displacement limitations in order to maintain the detector's critical alignment, thereby guaranteeing its operational integrity. This paper will present the results of this study, which has been issued to the Architect Engineer/Construction Manager as user requirements of design. The total structural system performance of the combination of both the detector and its foundation will be discussed

  9. Do talento ao alto rendimento: indicadores de acesso à excelência no handebol From talent to a high level of performance: key requirements to access the excellence in handball

    Directory of Open Access Journals (Sweden)

    Luís Massuça

    2010-12-01

    Full Text Available O talento constitui uma das condições fundamentais para acender à excelência no desporto de competição e a sua identificação representa o primeiro passo de um longo processo de especialização que permite selecionar os sujeitos certos. Para conhecer as variáveis que os treinadores julgam mais influentes no sucesso do atleta de handebol (do sexo masculino, foi aplicado um questionário a 71 treinadores de handebol ("Questionário aos Técnicos de Andebol - QTA"; MASSUÇA, 2007. Neste instrumento, solicitava-se aos participantes que avaliassem o grau de importância de cada fator e indicador de rendimento no sucesso em geral (Handebolista, A e, que o fizessem igualmente para cada uma das posições de jogo que caracterizam a modalidade desportiva (Ponta, P; Lateral, L; Central, C; Pivot, Pi; Guarda-redes, GR. Os resultados permitem constatar que não existe um perfil de atleta de handebol, mas vários. Pode assim concluir-se que no jogo de handebol o sucesso pode ser experimentado por atletas com diferentes características. Em complemento, julgamos que o inventário apresentado (das qualidades necessárias ao atleta de handebol de alto rendimento poderá servir de referência para a construção de um modelo de seleção de talentos.Talent is a key requirement to access the excellence in a competitive sport and its identification is the first step of a long process of specialization that allows the correct selection of subjects. To understand what the most influent variables to achieve success are, a questionnaire was administered to 71 handball coaches ("Questionnaire to Handball Coaches - QTA"; MASSUÇA, 2007. The coaches were asked to rate the importance of each factor and performance indicator considering the success of the general male handball player (A and to do exactly the same for each specific playing position (wing, P; backward left/right, L; backward centre, C; pivot, Pi; goalkeeper, GR. Results showed that there is not a

  10. Performance Characterization of UV Science Cameras Developed for the Chromospheric Lyman-Alpha Spectro-Polarimeter (CLASP)

    Science.gov (United States)

    Champey, Patrick; Kobayashi, Ken; Winebarger, Amy; Cirtin, Jonathan; Hyde, David; Robertson, Bryan; Beabout, Brent; Beabout, Dyana; Stewart, Mike

    2014-01-01

    The NASA Marshall Space Flight Center (MSFC) has developed a science camera suitable for sub-orbital missions for observations in the UV, EUV and soft X-ray. Six cameras will be built and tested for flight with the Chromospheric Lyman-Alpha Spectro-Polarimeter (CLASP), a joint National Astronomical Observatory of Japan (NAOJ) and MSFC sounding rocket mission. The goal of the CLASP mission is to observe the scattering polarization in Lyman-alpha and to detect the Hanle effect in the line core. Due to the nature of Lyman-alpha polarization in the chromosphere, strict measurement sensitivity requirements are imposed on the CLASP polarimeter and spectrograph systems; science requirements for polarization measurements of Q/I and U/I are 0.1% in the line core. CLASP is a dual-beam spectro-polarimeter, which uses a continuously rotating waveplate as a polarization modulator, while the waveplate motor driver outputs trigger pulses to synchronize the exposures. The CCDs are operated in frame-transfer mode; the trigger pulse initiates the frame transfer, effectively ending the ongoing exposure and starting the next. The strict requirement of 0.1% polarization accuracy is met by using frame-transfer cameras to maximize the duty cycle in order to minimize photon noise. Coating the e2v CCD57-10 512x512 detectors with Lumogen-E coating allows for a relatively high (30%) quantum efficiency at the Lyman-$\\alpha$ line. The CLASP cameras were designed to operate with =10 e- /pixel/second dark current, = 25 e- read noise, a gain of 2.0 and =0.1% residual non-linearity. We present the results of the performance characterization study performed on the CLASP prototype camera; dark current, read noise, camera gain and residual non-linearity.

  11. Simple and versatile turbidimetric monitoring of bacterial growth in liquid cultures using a customized 3D printed culture tube holder and a miniaturized spectrophotometer: application to facultative and strictly anaerobic bacteria

    Directory of Open Access Journals (Sweden)

    Margarida R. G. Maia

    2016-08-01

    Full Text Available Here we introduce a novel strategy for turbidimetric monitoring of bacterial growth in liquid culture. The instrumentation comprises a light source, a customized 3D printed culture tube holder and a miniaturized spectrophotometer, connected through optical cables. Due to its small footprint and the possibility to operate with external light, bacterial growth was directly monitored from culture tubes in a simple and versatile fashion. This new portable measurement technique was used to monitor the growth of facultative (Escherichia coli ATCC/25922, and Staphylococcus aureus ATCC/29213 and strictly (Butyrivibrio fibrisolvens JW11, Butyrivibrio proteoclasticus P18, and Propionibacterium acnes DSMZ 1897 anaerobic bacteria. For E. coli and S. aureus, the growth rates calculated from normalized optical density values were compared with those ones obtained using a benchtop spectrophotometer without significant differences (P = 0.256. For the strictly anaerobic species, a high precision (RSD < 3.5% was observed between replicates up to 48 h. Regarding its potential for customization, this manifold could accommodate further developments for customized turbidimetric monitoring, such as the use of light-emitting diodes as a light source or flow cells.

  12. Simple and Versatile Turbidimetric Monitoring of Bacterial Growth in Liquid Cultures Using a Customized 3D Printed Culture Tube Holder and a Miniaturized Spectrophotometer: Application to Facultative and Strictly Anaerobic Bacteria.

    Science.gov (United States)

    Maia, Margarida R G; Marques, Sara; Cabrita, Ana R J; Wallace, R John; Thompson, Gertrude; Fonseca, António J M; Oliveira, Hugo M

    2016-01-01

    Here we introduce a novel strategy for turbidimetric monitoring of bacterial growth in liquid culture. The instrumentation comprises a light source, a customized 3D printed culture tube holder and a miniaturized spectrophotometer, connected through optical cables. Due to its small footprint and the possibility to operate with external light, bacterial growth was directly monitored from culture tubes in a simple and versatile fashion. This new portable measurement technique was used to monitor the growth of facultative (Escherichia coli ATCC/25922, and Staphylococcus aureus ATCC/29213) and strictly (Butyrivibrio fibrisolvens JW11, Butyrivibrio proteoclasticus P18, and Propionibacterium acnes DSMZ 1897) anaerobic bacteria. For E. coli and S. aureus, the growth rates calculated from normalized optical density values were compared with those ones obtained using a benchtop spectrophotometer without significant differences (P = 0.256). For the strictly anaerobic species, a high precision (relative standard deviation < 3.5%) was observed between replicates up to 48 h. Regarding its potential for customization, this manifold could accommodate further developments for customized turbidimetric monitoring, such as the use of light-emitting diodes as a light source or flow cells.

  13. MUSCLE STRENGTH AND GOLF PERFORMANCE: A CRITICAL REVIEW

    Directory of Open Access Journals (Sweden)

    Lorena Torres-Ronda

    2011-03-01

    Full Text Available Golf has become an increasingly popular sport and a growing body of research trying to identify its main physical requirements is being published. The aim of this review was twofold: first, to examine the existing scientific literature regarding strength training and golf in healthy, non-injured, subjects; and second, to reach conclusions that could provide information on how to design more effective strength training programs to improve golf performance as well as directions for future research. Studies which analyzed the relationship between muscle strength, swing performance variables (club head speed, driving distance, ball speed and skill (handicap, score were reviewed. Changes in swing performance following different strength training programs were also investigated. Finally, a critical analysis about the methodologies used was carried out. The results of the reviewed studies seem to indicate that: 1 a positive relationship exists between handicap and swing performance (even though few studies have investigated this issue; 2 there is a positive correlation between skill (handicap and/or score and muscle strength; and 3 there is a relationship between driving distance, swing speed, ball speed and muscle strength. Results suggest that training leg-hip and trunk power as well as grip strength is especially relevant for golf performance improvement. Studies that analyzed variations in swing performance following resistance-only training programs are scarce, thus it is difficult to prove whether the observed improvements are attributable to changes in strength levels. Many of the studies reviewed presented some methodological errors in their design and not all strength assessment protocols seemed appropriate. Further studies should determine muscle strength needs in relation to final swing performance, using well designed experiments and strict isoinertial assessment protocols which adequately relate to specific golf motion, age and skill level

  14. SOCIAL INCLUSION AND SOLIDARITY IN STRICT POST-GRADUATION: EXPERIENCING THE LABORATORY "SCIENTIFIC WAKE FOR THE FUTURE" (PRIMARY AND SECONDARY EDUCATION).

    Science.gov (United States)

    Noronha, Silvana Aparecida Alves Corrêa de; Bernardes, Linda; Noronha, Samuel Marcos Ribeiro de; Nascimento, Fernanda Amorim de Morais; Ferreira, Lydia Masako

    2015-01-01

    To stimulate and awakening the interest of students of high school or elementary public schools in research and science through scientific initiation stages in the Postgraduate Program in Translational Surgery. To stimulate and awakening the interest of students of high school or elementary public schools in research and science through scientific initiation stages in the Postgraduate Program in Translational Surgery. The target audience for the development of scientific activities were students enrolled in mid-level course (second year initially) and have approval of their participation in this project by the school and by legal guardians. The inclusion criteria were: physical proximity to the higher education institution, signing the consent form by the legal responsible for the students, and for the board of the school unit and the researcher. Initially, students performed diagnostic evaluation about the prior knowledge of biology, science and scientific research. From there, the classes were prepared based on the result of this test, then started the activities of Junior Scientific Initiation in basic education. The school chosen for this initial phase of the pilot project was the State School Rui Bloem which has 13 classrooms for the second year of medium education in a total of 390 students. Of these, 160 (41%) were interested but only 16 (10%) were eligible to start the pilot project in Translational Surgery Laboratory of Unifesp. These students showed average yield of 50% in diagnostic test and should start the next training in cell and molecular biology laboratory and also to attend scientific meetings. In the initial phase of the project, was observed the great student interest in scientific career, but at the same time, a great need for improvement. The choice of public school was for access to university and proximity. In addition, these students have more shortcomings and deficiencies. But this does not mean that the fascination for scientific career

  15. Waste Management System Requirement document

    International Nuclear Information System (INIS)

    1990-04-01

    This volume defines the top level technical requirements for the Monitored Retrievable Storage (MRS) facility. It is designed to be used in conjunction with Volume 1, General System Requirements. Volume 3 provides a functional description expanding the requirements allocated to the MRS facility in Volume 1 and, when appropriate, elaborates on requirements by providing associated performance criteria. Volumes 1 and 3 together convey a minimum set of requirements that must be satisfied by the final MRS facility design without unduly constraining individual design efforts. The requirements are derived from the Nuclear Waste Policy Act of 1982 (NWPA), the Nuclear Waste Policy Amendments Act of 1987 (NWPAA), the Environmental Protection Agency's (EPA) Environmental Standards for the Management and Disposal of Spent Nuclear Fuel (40 CFR 191), NRC Licensing Requirements for the Independent Storage of Spent Nuclear and High-Level Radioactive Waste (10 CFR 72), and other federal statutory and regulatory requirements, and major program policy decisions. This document sets forth specific requirements that will be fulfilled. Each subsequent level of the technical document hierarchy will be significantly more detailed and provide further guidance and definition as to how each of these requirements will be implemented in the design. Requirements appearing in Volume 3 are traceable into the MRS Design Requirements Document. Section 2 of this volume provides a functional breakdown for the MRS facility. 1 tab

  16. Patrones de distribución de la flora vascular acuática estricta en el estado de Tamaulipas, México Distributional patterns of the strictly aquatic vascular flora in the state of Tamaulipas, Mexico

    Directory of Open Access Journals (Sweden)

    Arturo Mora-Olivo

    2008-12-01

    Full Text Available Se analizaron los patrones de riqueza y distribución de las plantas vasculares acuáticas estrictas en el estado de Tamaulipas, México. Se registraron 93 especies, 62 de las cuales son típicas de ambientes lénticos. La subcuenca Río Tamesí fue la que registró el mayor número de especies (68, 73.1%. No se registraron especies endémicas del estado, aunque existen 2 especies restringidas al territorio mexicano (Lobelia purpusii y Oserya coulteriana. Se consideran como raras 29 especies (31.2% por presentarse en una sola subcuenca y sólo 2 especies están distribuidas ampliamente en la mayoría de éstas (Bacopa monnieri y Echinodorus berteroi. Un análisis de parsimonia de endemismos (PAE de las subcuencas hidrológicas del estado con base en la presencia compartida de especies reveló que las plantas acuáticas estrictas presentan un patrón de distribución anidado. Se concluye que las plantas vasculares acuáticas estrictas de Tamaulipas son parte de una misma unidad florística y que su distribución obedece a gradientes altitudinales, latitudinales y climáticos.Patterns of distribution and richness of strictly aquatic vascular plants of the state of Tamaulipas, Mexico, were analyzed. We registered 93 species of strictly aquatic vascular plants, which 62 are typical from lentic environments. The Río Tamesí sub-basin contains the highest number of species (68, 73.1%. There are no endemic species to the state of Tamaulipas, but we found 2 species endemic to Mexico (Lobelia purpusii and Oserya coulteriana. Twenty nine species (31.2% are considered rare, because they are present in a single sub-basin; only 2 species are widely distributed in most of them (Bacopa monnieri and Echinodorus berteroi. A parsimony analysis of endemicity (PAE of the hydrological sub-basins represented in this state based on the shared presence of species suggested that the strictly aquatic vascular plants have a nested distributional pattern. We conclude that

  17. The Performance test of Mechanical Sodium Pump with Water Environment

    International Nuclear Information System (INIS)

    Cho, Chungho; Kim, Jong-Man; Ko, Yung Joo; Jeong, Ji-Young; Kim, Jong-Bum; Ko, Bock Seong; Park, Sang Jun; Lee, Yoon Sang

    2015-01-01

    As contrasted with PWR(Pressurized light Water Reactor) using water as a coolant, sodium is used as a coolant in SFR because of its low melting temperature, high thermal conductivity, the high boiling temperature allowing the reactors to operate at ambient pressure, and low neutron absorption cross section which is required to achieve a high neutron flux. But, sodium is violently reactive with water or oxygen like the other alkali metal. So Very strict requirements are demanded to design and fabricate of sodium experimental facilities. Furthermore, performance testing in high temperature sodium environments is more expensive and time consuming and need an extra precautions because operating and maintaining of sodium experimental facilities are very difficult. The present paper describes performance test results of mechanical sodium pump with water which has been performed with some design changes using water test facility in SAM JIN Industrial Co. To compare the hydraulic characteristic of model pump with water and sodium, the performance test of model pump were performed using vender's experimental facility for mechanical sodium pump. To accommodate non-uniform thermal expansion and to secure the operability and the safety, the gap size of some parts of original model pump was modified. Performance tests of modified mechanical sodium pump with water were successfully performed. Water is therefore often selected as a surrogate test fluid because it is not only cheap, easily available and easy to handle but also its important hydraulic properties (density and kinematic viscosity) are very similar to that of the sodium. Normal practice to thoroughly test a design or component before applied or installed in reactor is important to ensure the safety and operability in the sodium-cooled fast reactor (SFR). So, in order to estimate the hydraulic behavior of the PHTS pump of DSFR (600 MWe Demonstraion SFR), the performance tests of the model pump such as performance

  18. Does Drinking Impair College Performance? Evidence from a Regression Discontinuity Approach. NBER Working Paper No. 16330

    Science.gov (United States)

    Carrell, Scott E.; Hoekstra, Mark; West, James E.

    2010-01-01

    This paper examines the effect of alcohol consumption on student achievement. To do so, we exploit the discontinuity in drinking at age 21 at a college in which the minimum legal drinking age is strictly enforced. We find that drinking causes significant reductions in academic performance, particularly for the highest-performing students. This…

  19. Avionics System Performance Management

    National Research Council Canada - National Science Library

    Damania, Bhavesh

    1998-01-01

    .... The reasons for improved performance management include advances in processor technology and architectures, increasingly integrated systems, and the requirement of reducing costs in developing and deploying the systems...

  20. "Strict" Anadeixis, Discourse Deixis and Text Structuring

    Science.gov (United States)

    Cornish, Francis

    2011-01-01

    Taking English as the example language, the article begins by presenting a Scale of indexicality characterizing context-bound expression types, ranging from those signalling pure deixis at one pole, to ones expressing pure anaphora at the other. On the basis of this Scale, the article attempts to determine the specific way in which demonstratives…

  1. Unconditional bases and strictly convex dual renormings

    Czech Academy of Sciences Publication Activity Database

    Smith, Richard James; Troyanski, S.

    2009-01-01

    Roč. 41, č. 5 (2009), s. 831-840 ISSN 0024-6093 R&D Projects: GA AV ČR IAA100190801; GA ČR GA201/07/0394 Institutional research plan: CEZ:AV0Z10190503 Keywords : descroptive compact spaces * Banach spaces * norms Subject RIV: BA - General Mathematics Impact factor: 0.757, year: 2009 http://blms.oxfordjournals.org/content/41/5/831

  2. On Fixed Points of Strictly Causal Functions

    Science.gov (United States)

    2013-04-08

    languages such as VHDL (see [1]) and SystemC (see [2]), modeling and simulation tools such as Simulink and LabVIEW, network simulation tools such as ns-2/ns...interesting direction for future 49 work. References [1] IEEE standard VHDL language reference manual. IEEE Std 1076-2000, pages i–290, 2000. [2] IEEE

  3. Strictly convex functions on complete Finsler manifolds

    Indian Academy of Sciences (India)

    minimum set of a super Busemann function contains a soul of M. Clearly, a complete simply connected Riemannian manifold H of non-positive sec- tional curvature, called Hadamard manifold, has the property that the distance function to an arbitrary fixed point is strongly convex exhaustion. Also, the exponential map expp :.

  4. Strictly convex functions on complete Finsler manifolds

    Indian Academy of Sciences (India)

    convex functions on the metric structures of complete Finsler manifolds. More precisely we discuss ... map expp at some point p ∈ M (and hence at every point on M) is defined on the whole tangent space Mp to M at ... The influence of the existence of convex functions on the metric and topology of under- lying manifolds has ...

  5. Performing Performance Design Anglonationally

    DEFF Research Database (Denmark)

    2016-01-01

    Video recording of pecha kucha style bricolage aural enactment of an international version of performance design......Video recording of pecha kucha style bricolage aural enactment of an international version of performance design...

  6. 40 CFR 63.707 - Reporting requirements.

    Science.gov (United States)

    2010-07-01

    ... proposed limit; and (iv) A statement signed by a responsible official of the company that the control... monitoring system performance report and summary reports shall be submitted as required by § 63.10(e). (1... the performance test required by § 63.7: (i) The performance test or CEM data collected to establish...

  7. Requirement analysis of the safety-critical software implementation for the nuclear power plant

    International Nuclear Information System (INIS)

    Chang, Hoon Seon; Jung, Jae Cheon; Kim, Jae Hack; Nam, Sang Ku; Kim, Hang Bae

    2005-01-01

    The safety critical software shall be implemented under the strict regulation and standards along with hardware qualification. In general, the safety critical software has been implemented using functional block language (FBL) and structured language like C in the real project. Software design shall comply with such characteristics as; modularity, simplicity, minimizing the use of sub-routine, and excluding the interrupt logic. To meet these prerequisites, we used the computer-aided software engineering (CASE) tool to substantiate the requirements traceability matrix that were manually developed using Word processors or Spreadsheets. And the coding standard and manual have been developed to confirm the quality of software development process, such as; readability, consistency, and maintainability in compliance with NUREG/CR-6463. System level preliminary hazard analysis (PHA) is performed by analyzing preliminary safety analysis report (PSAR) and FMEA document. The modularity concept is effectively implemented for the overall module configurations and functions using RTP software development tool. The response time imposed on the basis of the deterministic structure of the safety-critical software was measured

  8. Feed tank transfer requirements

    International Nuclear Information System (INIS)

    Freeman-Pollard, J.R.

    1998-01-01

    This document presents a definition of tank turnover; DOE responsibilities; TWRS DST permitting requirements; TWRS Authorization Basis (AB) requirements; TWRS AP Tank Farm operational requirements; unreviewed safety question (USQ) requirements; records and reporting requirements, and documentation which will require revision in support of transferring a DST in AP Tank Farm to a privatization contractor for use during Phase 1B

  9. Design requirement on HYPER blanket fuel assembly

    International Nuclear Information System (INIS)

    Hwang, Woan; Lee, B. O.; Nam, C.; Ryu, W. S.; Lee, B. S.; Park, W. S.

    2000-07-01

    This document describes design requirements which are needed for designing the blanket assembly of the HYPER as design guidance. The blanket assembly of the HYPER consists of blanket fuel rods, mounting rail, spacer, upper nozzle with handling socket, bottom nozzle with mounting rail and skeleton structure. The blanket fuel rod consists of top end plug, bottom end plug with key way, blanket fuel slug, and cladding. In the assembly, the rods are in a triangular pitch array. This report contains functional requirements, performance and operational requirements, interfacing systems requirements, core restraint and interface requirements, design limits and strength requirements, system configuration and essential feature requirements, seismic requirements, structural requirements, environmental requirements, reliability and safety requirements, standard and codes, QA programs, and other requirements for the blanket fuel assembly of the HYPER

  10. ArControl: An Arduino-Based Comprehensive Behavioral Platform with Real-Time Performance.

    Science.gov (United States)

    Chen, Xinfeng; Li, Haohong

    2017-01-01

    Studying animal behavior in the lab requires reliable delivering stimulations and monitoring responses. We constructed a comprehensive behavioral platform (ArControl: Arduino Control Platform) that was an affordable, easy-to-use, high-performance solution combined software and hardware components. The hardware component was consisted of an Arduino UNO board and a simple drive circuit. As for software, the ArControl provided a stand-alone and intuitive GUI (graphical user interface) application that did not require users to master scripts. The experiment data were automatically recorded with the built in DAQ (data acquisition) function. The ArControl also allowed the behavioral schedule to be entirely stored in and operated on the Arduino chip. This made the ArControl a genuine, real-time system with high temporal resolution (<1 ms). We tested the ArControl, based on strict performance measurements and two mice behavioral experiments. The results showed that the ArControl was an adaptive and reliable system suitable for behavioral research.

  11. ArControl: An Arduino-Based Comprehensive Behavioral Platform with Real-Time Performance

    Directory of Open Access Journals (Sweden)

    Xinfeng Chen

    2017-12-01

    Full Text Available Studying animal behavior in the lab requires reliable delivering stimulations and monitoring responses. We constructed a comprehensive behavioral platform (ArControl: Arduino Control Platform that was an affordable, easy-to-use, high-performance solution combined software and hardware components. The hardware component was consisted of an Arduino UNO board and a simple drive circuit. As for software, the ArControl provided a stand-alone and intuitive GUI (graphical user interface application that did not require users to master scripts. The experiment data were automatically recorded with the built in DAQ (data acquisition function. The ArControl also allowed the behavioral schedule to be entirely stored in and operated on the Arduino chip. This made the ArControl a genuine, real-time system with high temporal resolution (<1 ms. We tested the ArControl, based on strict performance measurements and two mice behavioral experiments. The results showed that the ArControl was an adaptive and reliable system suitable for behavioral research.

  12. Performance Monitoring Based on UML Performance Profile

    Science.gov (United States)

    Kim, Dong Kwan; Kim, Chul Jin; Cho, Eun Sook

    In this paper we propose a way of measuring software performance metrics such as response time, throughput, and resource utilization. It is obvious that performance-related Quality of Service (QoS) is one of the important factors which are satisfied for users' needs. The proposed approach uses UML performance profile for the performance specification and aspect-oriented paradigm for the performance measurement. Code instrumentation in AOP is a mechanism to insert source code for performance measurement into business logic code. We used AspectJ, an aspect-oriented extension to the Java. AspectJ code for performance measurement is separated from Java code for functional requirements. Both AspectJ and Java code can be woven together for the performance measurement. The key component of the proposed approach is an AspectJ code generator. It creates AspectJ code for the performance measurement from the UML [1] models containing performance profile.

  13. Feed tank transfer requirements

    Energy Technology Data Exchange (ETDEWEB)

    Freeman-Pollard, J.R.

    1998-09-16

    This document presents a definition of tank turnover. Also, DOE and PC responsibilities; TWRS DST permitting requirements; TWRS Authorization Basis (AB) requirements; TWRS AP Tank Farm operational requirements; unreviewed safety question (USQ) requirements are presented for two cases (i.e., tank modifications occurring before tank turnover and tank modification occurring after tank turnover). Finally, records and reporting requirements, and documentation which will require revision in support of transferring a DST in AP Tank Farm to a privatization contractor are presented.

  14. Development of NPP Safety Requirements into Kenya's Grid Codes

    International Nuclear Information System (INIS)

    Ndirangu, Nguni James; Koo, Chang Choong

    2015-01-01

    As presently drafted, Kenya's grid codes do not contain any NPP requirements. Through case studies of selected grid codes, this paper will study frequency, voltage and fault ride through requirements for NPP connection and operation, and offer recommendation of how these requirements can be incorporated in the Kenya's grid codes. Voltage and frequency excursions in Kenya's grid are notably frequently outside the generic requirement and the values observed by the German and UK grid codes. Kenya's grid codes require continuous operation for ±10% of nominal voltage and 45.0 to 52Hz on the grid which poses safety issues for an NPP. Considering stringent NPP connection to grid and operational safety requirements, and the importance of the TSO to NPP safety, more elaborate requirements need to be documented in the Kenya's grid codes. UK and Germany have a history of meeting high standards of nuclear safety and it is therefore recommended that format like the one in Table 1 to 3 should be adopted. Kenya's Grid code considering NPP should have: • Strict rules for voltage variation, that is, -5% to +10% of the nominal voltage • Strict rules for frequency variation, that is, 48Hz to 52Hz of the nominal frequencyand

  15. Human Computer Music Performance

    OpenAIRE

    Dannenberg, Roger B.

    2012-01-01

    Human Computer Music Performance (HCMP) is the study of music performance by live human performers and real-time computer-based performers. One goal of HCMP is to create a highly autonomous artificial performer that can fill the role of a human, especially in a popular music setting. This will require advances in automated music listening and understanding, new representations for music, techniques for music synchronization, real-time human-computer communication, music generation, sound synt...

  16. Requirement for digestible calcium by 25 to 50 kg pigs at different dietary concentrations of phosphorus as indicated by growth performance, bone ash concentration, and calcium and phosphorus balances.

    Science.gov (United States)

    González-Vega, J C; Walk, C L; Murphy, M R; Stein, H H

    2016-12-01

    Two experiments were conducted to determine the requirement for standardized total tract digestible (STTD) Ca by 25 to 50 kg pigs at different concentrations of STTD P. Twenty corn-soybean meal based diets were formulated with diets containing 4 concentrations of STTD P (0.15, 0.31, 0.39, or 0.47%) and 5 concentrations of STTD Ca (0.13, 0.27, 0.42, 0.57, or 0.72%). Diets were mixed in 1 batch and were used in both experiments. In Exp. 1, 240 pigs (initial average BW: 24.70 ± 1.27 kg) were randomly allotted to the 20 diets in 6 blocks with 1 pen per diet in each block using a 4 × 5 factorial design. There was 1 gilt and 1 barrow in each pen. At the conclusion of the 28 d experiment, all barrows were euthanized and the right femur was collected. Results indicated that there were interactions ( urine samples were collected. Results indicated that the predicted maximum retention of Ca in the body at STTD P concentrations of 0.15, 0.31, 0.39, and 0.47% were 4.7, 7.1, 8.6, and 10.2 g/d at STTD Ca concentrations of 0.77, 0.96, 1.06, and 1.15%, respectively, which correspond to STTD Ca:STTD P ratios of 5.13:1, 3.10:1, 2.72:1, and 2.45:1. These observations indicate that if STTD P meets or exceeds the requirement, the STTD Ca:STTD P ratio needed to maximize ADG and G:F by 25 to 50 kg pigs is between 1.16:1 and 1.43:1. However, a greater ratio may be needed to maximize bone ash or Ca retention.

  17. 10 CFR 61.40 - General requirement.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false General requirement. 61.40 Section 61.40 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Performance Objectives § 61.40 General requirement. Land disposal facilities must be sited, designed, operated, closed...

  18. Formalizing Theatrical Performances Using Multi-Agent Organizations

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt; Spurkeland, Johannes Svante; Villadsen, Jørgen

    2013-01-01

    Theatrical performances usually follow strict scripts and actors are not allowed to deviate. A Danish theatrical group, Theater 770◦ Celsius, has invented a new method called In Real Life, in which only certain events in the storyline are specified and the actors are supposed to improvise to reac...... these events. The method bears a resemblance to multi-agent systems and we show how it can be formalized using the multi-agent organizational model OperA....

  19. Praise in Public, Criticize in Private? An Assessment of Performance Feedback Transparency in a Classroom Setting

    Science.gov (United States)

    Seevers, Matthew T.; Rowe, William J.; Skinner, Steven J.

    2014-01-01

    Conventional wisdom in sales management encourages public delivery of positive feedback, and private delivery of negative feedback. In stark contrast, U.S. educators typically provide all performance feedback in relative (if not strict) privacy to comply with the Family Educational Rights and Privacy Act (FERPA). To investigate this discrepancy,…

  20. EMPIRICAL RESEARCH ON THE STRUCTURE OF A SYSTEM FOR ASSESSMENT OF THE GLOBAL PERFORMANCE OF ECONOMIC ENTITIES

    Directory of Open Access Journals (Sweden)

    Pintea Mirela-Oana

    2012-07-01

    Full Text Available Sustainable development and, therefore, globalization require new standards of performance that exceeds the economic field, both for domestic companies as well as international ones. So, these standards should be integrated into corporate strategy development to ensure sustainability of activities undertaken by harmonizing the economic, social and environmental objectives. For sustainable development of an entity, value creation can not be seen in strictly financial terms, therefore any strategies that are defined by entities concerns not only the quantitative aspects (economic-financial but also qualitative aspects (social and environmental. This study attempts to address the issue of building a set of indicators to assess overall performance and it stops at each of the three dimensions of performance, namely economic performance, social performance and environmental performance. In this scientific approach we try to stop on one of the priorities of economic research that is finding indicators that better reflect the three dimensions of performance. What indicators would best represent the overall performance?, What indicators would best represent the financial performance?, What indicators would best represent social performance?, What would be the best indicators of environmental performance? During this scientific approach will try to answer each of these questions through the empirical research conducted. To do this research we focused on statistical population consisting of the following categories of analysts: analysts from academic environment (Cluj-Napoca, Bucharest, Timisoara, Iasi, Craiova, Sibiu, Pitesti, Galati and financial analysts from the specific departments of the Financial Investment Services Company (Broker SA, BT Securities, Target Capital, Tradeville, Estinvest, Intercapital, KBC Securities, etc.. This distinction was made because we believe that in determining the optimal structure of such a model we need the views of