WorldWideScience

Sample records for street chicago il

  1. 78 FR 46810 - Safety Zone; Motion Picture Filming; Chicago River; Chicago, IL

    Science.gov (United States)

    2013-08-02

    ... portion of the Chicago River due to the filming of a motion picture. These temporary safety zones are...-AA00 Safety Zone; Motion Picture Filming; Chicago River; Chicago, IL AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing three temporary safety [[Page 46811

  2. 78 FR 27304 - Safety Zone; Melrose Pyrotechnics Fireworks Display; Chicago Harbor, Chicago, IL

    Science.gov (United States)

    2013-05-10

    ... environmental risk to health or risk to safety that may disproportionately affect children. 11. Indian Tribal... Pier in Chicago Harbor, Chicago, IL. The Captain of the Port, Lake Michigan, has determined that these fireworks displays will pose a significant risk to public safety and property. Such hazards include falling...

  3. 75 FR 45478 - Safety Zone; Transformers 3 Movie Filming, Chicago River, Chicago, IL

    Science.gov (United States)

    2010-08-03

    ...-AA00 Safety Zone; Transformers 3 Movie Filming, Chicago River, Chicago, IL AGENCY: Coast Guard, DHS... the different types of stunts that will be performed during the filming of this movie. DATES... our analyses based on 13 of these statutes or executive orders. Regulatory Planning and Review This...

  4. 75 FR 41760 - Safety Zone; Transformers 3 Movie Filming, Chicago River, Chicago, IL

    Science.gov (United States)

    2010-07-19

    ...-AA00 Safety Zone; Transformers 3 Movie Filming, Chicago River, Chicago, IL AGENCY: Coast Guard, DHS... that will be performed during the filming of this movie. DATES: Effective Date: this rule is effective.... Regulatory Planning and Review This rule is not a significant regulatory action under section 3(f) of...

  5. 76 FR 58108 - Safety Zone; Ryder Cup Captain's Duel Golf Shot, Chicago River, Chicago, IL

    Science.gov (United States)

    2011-09-20

    ...-AA00 Safety Zone; Ryder Cup Captain's Duel Golf Shot, Chicago River, Chicago, IL AGENCY: Coast Guard... the Chicago River during a golfing event that will involve hitting golf balls from land onto a... vessels from the hazards associated with golf balls being hit from land onto a stationary barge in the...

  6. 33 CFR 100.909 - Chinatown Chamber of Commerce Dragon Boat Race; Chicago, IL.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Chinatown Chamber of Commerce Dragon Boat Race; Chicago, IL. 100.909 Section 100.909 Navigation and Navigable Waters COAST GUARD... Chinatown Chamber of Commerce Dragon Boat Race; Chicago, IL. (a) Regulated Area. All waters of the South...

  7. 77 FR 55139 - Safety Zone; Chicago Red Bull Flugtag, Lake Michigan, Chicago, IL

    Science.gov (United States)

    2012-09-07

    ..., Protection of Children from Environmental Health Risks and Safety Risks. This rule is not an economically significant rule and does not create an environmental risk to health or risk to safety that may..., Chicago, IL. The Captain of the Port, Sector Lake Michigan, has determined that the Red Bull Flugtag event...

  8. C. Walker-Said and J. D. Kelly (eds), Corporate Social Responsibility? Human Rights in the New Global Economy (Chicago, IL: The University of Chicago Press, 2015), 392 pp

    DEFF Research Database (Denmark)

    Whelan, Glen

    2017-01-01

    Book review of: Charlotte Walker-Said and John D. Kelly (eds), Corporate Social Responsibility? Human Rights in the New Global Economy (Chicago, IL: The University of Chicago Press, 2015), 392 pp.......Book review of: Charlotte Walker-Said and John D. Kelly (eds), Corporate Social Responsibility? Human Rights in the New Global Economy (Chicago, IL: The University of Chicago Press, 2015), 392 pp....

  9. 76 FR 11334 - Safety Zone; Soil Sampling; Chicago River, Chicago, IL

    Science.gov (United States)

    2011-03-02

    ...The Coast Guard is establishing a temporary safety zone on the North Branch of the Chicago River near Chicago, Illinois. This zone is intended to restrict vessels from a portion of the North Branch of the Chicago River due to soil sampling in this area. This temporary safety zone is necessary to protect the surrounding public and vessels from the hazards associated with the soil sampling efforts.

  10. 75 FR 435 - Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL

    Science.gov (United States)

    2010-01-05

    ... Natural History, Chicago, IL. The human remains were removed from the Channel Islands in Santa Barbara and.... A detailed assessment of the human remains was made by Field Museum of Natural History professional... 407). The human remains were accessioned into the Field Museum of Natural History the same year. No...

  11. 75 FR 45659 - Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL

    Science.gov (United States)

    2010-08-03

    ... possession of the Field Museum of Natural History, Chicago, IL. The human remains and associated funerary... assessment of the human remains was made by the Field Museum of Natural History professional staff in... History have determined that, pursuant to 25 U.S.C. 3001(9), the human remains described above represent...

  12. 75 FR 4343 - Foreign-Trade Zone 22-Chicago, IL; Application for Manufacturing Authority; LG Electronics...

    Science.gov (United States)

    2010-01-27

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket 3-2010] Foreign-Trade Zone 22--Chicago, IL; Application for Manufacturing Authority; LG Electronics MobileComm USA, Inc. (Cell Phone Kitting... authority on behalf of LG Electronics MobileComm USA, Inc. (LGEMU), located in Bolingbrook, Illinois. The...

  13. 78 FR 34130 - Notice of Intent to Repatriate Cultural Items: The Field Museum, Chicago, IL

    Science.gov (United States)

    2013-06-06

    ... Indian tribes or Native Hawaiian organizations, has determined that the cultural items listed in this... tribe or Native Hawaiian organization not identified in this notice that wish to claim these cultural....R50000] Notice of Intent to Repatriate Cultural Items: The Field Museum, Chicago, IL AGENCY: National...

  14. 77 FR 75610 - Foreign-Trade Zone 22-Chicago, IL, Notification of Proposed Production Activity, Abbott...

    Science.gov (United States)

    2012-12-21

    ..., Notification of Proposed Production Activity, Abbott Laboratories, Inc., AbbVie, Inc. (Pharmaceutical Production), North Chicago, IL, Area Abbott Laboratories, Inc. (Abbott) and AbbVie, Inc. (AbbVie) submitted a... Abbott facilities to AbbVie, now designated as Subzone 22S (S-66-2012). Abbott and Abbvie are now...

  15. 77 FR 47918 - Chicago Central and Pacific Railroad Company-Abandonment Exemption-in Cook County, IL

    Science.gov (United States)

    2012-08-10

    ... Central and Pacific Railroad Company--Abandonment Exemption--in Cook County, IL Chicago Central and... North Riverside, Cook County, Ill. The line traverses United States Postal Service Zip Codes 60546 and... system. A copy of any petition filed with the Board should be sent to CCP's representative: Thomas J...

  16. 76 FR 34145 - Safety Zone, Barrier Testing Operations, Chicago Sanitary and Ship Canal, Romeoville, IL

    Science.gov (United States)

    2011-06-13

    ...-AA00 Safety Zone, Barrier Testing Operations, Chicago Sanitary and Ship Canal, Romeoville, IL AGENCY.... Construction on Barrier IIB has been completed. Operational and safety testing was conducted in February 2011... dispersal barrier IIA and IIB. This safety zone will be enforced daily from 7 a.m. to 11 a.m. and from 1 p.m...

  17. 75 FR 39460 - Prevailing Rate Systems; Redefinition of the Chicago, IL; Fort Wayne-Marion, IN; Indianapolis, IN...

    Science.gov (United States)

    2010-07-09

    ...-AM21 Prevailing Rate Systems; Redefinition of the Chicago, IL; Fort Wayne-Marion, IN; Indianapolis, IN... wage area. These changes are based on recent consensus recommendations of the Federal Prevailing Rate... below. The Federal Prevailing Rate Advisory Committee (FPRAC), the national labor-management committee...

  18. Elastomeric Materials for Acoustical Applications

    Science.gov (United States)

    1989-09-15

    fluorine . The classes of materials marketed as Fluorel and Viton by 3M and DuPont, respectively, are copolymers of vinylidene fluoride and...Street Sullivan Varnish Co. Chicago, IL 60632 420 N. Hiart Street- (312) 523-1412 Chicago, IL 60622 (312) 666-8080 Testworth Laboratories, Inc. 139

  19. 75 FR 36288 - Amended Safety Zone and Regulated Navigation Area, Chicago Sanitary and Ship Canal, Romeoville, IL

    Science.gov (United States)

    2010-06-25

    ...The Coast Guard is revising its safety zone and Regulated Navigation Area (RNA) on the Chicago Sanitary and Ship Canal (CSSC) near Romeoville, IL. This revised temporary interim rule reduces the areas covered by the safety zone and RNA, and places additional restrictions on vessels that may transit the RNA.

  20. 78 FR 21413 - Notice of Intent To Repatriate Cultural Items: The Field Museum of Natural History, Chicago, IL

    Science.gov (United States)

    2013-04-10

    ... cultural items listed in this notice meet the definition of sacred objects and objects of cultural... Natural History, Chicago, IL, that meet the definition of sacred objects and objects of cultural patrimony... ``Apache's Medicine-man's effigy.'' Charles Owen had previously seen the figure on the Apache Reservation...

  1. 77 FR 65896 - Award of a Single-Source Replacement Grant to SOS Children's Villages Illinois in Chicago, IL

    Science.gov (United States)

    2012-10-31

    ....623] Award of a Single-Source Replacement Grant to SOS Children's Villages Illinois in Chicago, IL... (FYSB) announces the award of a single-source replacement grant to SOS Children's Villages Illinois in... grant. ACYF/FYSB has designated SOS Children's Villages Illinois, a 501(c)(3) non-profit organization...

  2. 33 CFR 165.T09-1080 - Safety Zone and Regulated Navigation Area, Chicago Sanitary and Ship Canal, Romeoville, IL.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety Zone and Regulated Navigation Area, Chicago Sanitary and Ship Canal, Romeoville, IL. 165.T09-1080 Section 165.T09-1080 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED...

  3. 78 FR 5800 - Clean Water Act Class II: Proposed Administrative Settlement, Penalty Assessment and Opportunity...

    Science.gov (United States)

    2013-01-28

    ... P110. 2 IL-52R 5201 Rose Street...... Chicago IL. 3 MA-SUM 1 Summer Street....... Boston MA. 4 PA-401... Commission (LEPC), the State Emergency Response Commission (SERC), and/or the fire department with...

  4. "American" Abjection: "Chicanos," Gangs, and Mexican/Migrant Transnationality in Chicago

    Science.gov (United States)

    De Genova, Nicholas

    2008-01-01

    Crime and street violence often evoke racialized discourses about urban space. In this ethnographic research in Chicago, however, the disdain that many Mexican migrants articulated about street gangs principally concerned issues "internal" to the Mexican/Chicano community, notably a profound ambivalence about U.S.-born Mexicans and a…

  5. 76 FR 35227 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-06-16

    ... Special Emphasis Panel; Small Business: Non-HIV Diagnostics, Food Safety, Sterilization/Disinfection and... applications. Place: Avenue Crowne Plaza Hotel, 160 East Huron, Chicago, IL 60611. Contact Person: Gagan Pandya...: Avenue Crowne Plaza Hotel and Suites, 160 East Huron Street, Chicago, IL 60611. Contact Person: Kenneth M...

  6. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Saint Clair Street Chicago, IL 60611-3295 Toll free: 800-621-4111 (P) 312-202-5000 (F) 312-202-5001 (E) postmaster@facs.org Copyright © 1996-2018 by the American College of Surgeons, Chicago, IL 60611-3295 | Privacy Policy | Terms of Use

  7. Your Lung Operation: After Your Operation

    Medline Plus

    Full Text Available ... Saint Clair Street Chicago, IL 60611-3295 Toll free: 800-621-4111 (P) 312-202-5000 (F) 312-202-5001 (E) postmaster@facs.org Copyright © 1996-2018 by the American College of Surgeons, Chicago, IL 60611-3295 | Privacy Policy | Terms of Use

  8. 78 FR 64968 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-30

    ... Biology and Technology Study Section, October 16, 2013, 8:30 a.m. to October 17, 2013, 1:00 p.m., Avenue Hotel Chicago, 160 E. Huron Street, Chicago, IL 60611 which was published in the Federal Register on...

  9. 75 FR 32955 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-06-10

    ... evaluate grant applications. Place: Ritz Carlton Hotel, 1150 22nd Street, NW., Washington, DC 20037... grant applications. Place: Ritz-Carlton Hotel, 1150 22nd Street, NW., Boardroom, Washington, DC 20037... Hotel, 701 North Michigan Avenue, Chicago, IL 60611. Contact Person: Biao Tian, PhD, Scientific Review...

  10. Making Health Easier: Healthy Schools in Chicago, IL PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2013-05-21

    To help Chicago schools increase access to healthy food, Health Educator April Lillstrom utilized community partnerships to provide school gardens, salad bars, and nutrition education to students.  Created: 5/21/2013 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 5/21/2013.

  11. 40 CFR 59.409 - Addresses of EPA Offices.

    Science.gov (United States)

    2010-07-01

    ..., Tennessee), Director, Air, Pesticides, and Toxics Management Division, 61 Forsyth Street, Atlanta, GA 30303... Division, 77 West Jackson Boulevard, Chicago, IL 60604-3507. EPA Region VI (Arkansas, Louisiana, New Mexico...

  12. Fertility Preservation for Children Diagnosed with Cancer

    Medline Plus

    Full Text Available ... Northwestern University Careers Disclaimer Campus Emergency Information University Policies Oncofertility Consortium 303 E Superior Street, Suite 10-121 Chicago, IL, 60611 (312) 503-2504 Social Media Parking Maps Shuttles Directory Bookstore Library

  13. Fertility Preservation for Children Diagnosed with Cancer

    Medline Plus

    Full Text Available ... Contact Northwestern University Careers Disclaimer Campus Emergency Information University Policies Oncofertility Consortium 303 E Superior Street, Suite 10-121 Chicago, IL, 60611 (312) 503-2504 Social Media Parking Maps Shuttles Directory Bookstore Library

  14. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... You Want to Be a Surgeon Resident Resources Teaching Resources Online Guide to Choosing a Surgical Residency ... Shop My Profile American College of Surgeons 633 N Saint Clair Street Chicago, IL 60611-3295 Toll ...

  15. Your Lung Operation: After Your Operation

    Medline Plus

    Full Text Available ... You Want to Be a Surgeon Resident Resources Teaching Resources Online Guide to Choosing a Surgical Residency ... Shop My Profile American College of Surgeons 633 N Saint Clair Street Chicago, IL 60611-3295 Toll ...

  16. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... About OGB Volunteer and Partner Portal Domestic Surgical Free Access Clinics Opportunities Resources and Toolkits Surgical Volunteerism ... Saint Clair Street Chicago, IL 60611-3295 Toll free: 800-621-4111 (P) 312-202-5000 (F) ...

  17. Your Lung Operation: After Your Operation

    Medline Plus

    Full Text Available ... About OGB Volunteer and Partner Portal Domestic Surgical Free Access Clinics Opportunities Resources and Toolkits Surgical Volunteerism ... Saint Clair Street Chicago, IL 60611-3295 Toll free: 800-621-4111 (P) 312-202-5000 (F) ...

  18. Review of The Chicago Guide to Writing about Numbers by Jane E. Miller

    Directory of Open Access Journals (Sweden)

    Neil Lutsky

    2009-01-01

    Full Text Available Miller, J. E. 2004. The Chicago Guide to Writing about Numbers. Chicago, IL: University of Chicago Press. 304 pp. Cloth $45 ISBN: 9780226526300, Softcover $17. ISBN: 9780226526317.The Chicago Guide to Writing about Numbers is a reference work suitable for anyone interested in understanding, using, or promoting quantitative thinking. Its primary aim is to identify and illustrate ways in which information associated with numbers can be conveyed most effectively given a particular communication purpose and context. The book is directed at writers who incorporate numbers in verbal or visual displays in documents, in oral presentations, or on the Web. The Chicago Guide to Writing about Numbers identifies overarching principles, offers concrete advice, and presents illuminating examples and models. The book can be used for instructional purposes for undergraduates, and a means of doing so is described. The review concludes by considering the book’s contributions to a wider call to help citizens write or argue more effectively by using numbers.

  19. Libraries in Illinois: MedlinePlus

    Science.gov (United States)

    ... John H. Stroger, Jr. Hospital of Cook County Academic Center-Library 1900 West Polk Street 2nd floor Chicago, IL ... 312-864-0506 http://www.cookcountyhhs.org/educationresearch/academic-center-library/ Shriners Hospitals for Children Professional Library 2211 North ...

  20. 76 FR 23524 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2011-04-27

    ...-AA00 Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago... safety zone from Brandon Road Lock and Dam to Lake Michigan. This proposed safety zone will cover 77.... This TIR established a 77 mile long safety zone from Brandon Road Lock to Lake Michigan in Chicago, IL...

  1. Enhancing Quality of Orthotic Services with Process and Outcome Information

    Science.gov (United States)

    2017-10-01

    PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Allen Heinemann-----Principal Investigator 5e. TASK NUMBER E -Mail:aheinemann@sralab.org 5f...of Chicago dba Shirley Ryan AbilityLab 355 E . Erie Street, Chicago, IL 60611 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10...Name and address of the Funding Agency’s Procuring Contracting/Grants Officer: Vera Pollard USA MED RESEARCH ACQ ACTIVITY Fort Detrick MD 21702

  2. 75 FR 18841 - Office for Civil Rights; Privacy Act of 1974, Amended System of Records

    Science.gov (United States)

    2010-04-13

    ... measures to mitigate damage to automated information system resources caused by fire, electricity, water... mitigate damage to automated information system resources caused by fire, electricity, water, and.... Michigan Ave, Suite 240, Chicago, IL 60601. Region VI, Regional Manager, OCR/HHS, 1301 Young Street, Suite...

  3. 76 FR 56157 - University of Chicago, et al.; Notice of Decision on Applications for Duty-Free Entry of...

    Science.gov (United States)

    2011-09-12

    .... Instrument: Magneto-optical Kerr Microscope System. Manufacturer: Evico Magnetics GmgH, Germany. Intended Use... Biology, Chicago, IL 60637. Instrument: Digital Scanned Laser Microscope. Manufacturer: Emblem GMBH...

  4. Commercial Maritime Information: A Critical Appraisal.

    Science.gov (United States)

    1981-01-01

    Arthur Howard, Chief Inspector U.S. Customs Service, 555 Battery Street, San Francisco, CA 94111 Peter Mel Hughes , Traffic Manager, Port of Richmond...832, Federal Bldg. 10-A, Washington, DC 20591 Perla Londers, Trans-America Realco, 175 W. Jackman Blvd., Chicago, IL 60604 Edward M. MacCutcheon

  5. 75 FR 64393 - Approval of Noise Compatibility Program for Chicago Executive Airport, Prospect Heights and...

    Science.gov (United States)

    2010-10-19

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Approval of Noise Compatibility Program for Chicago Executive Airport, Prospect Heights and Wheeling, IL AGENCY: Federal Aviation Administration, DOT. ACTION: Notice. SUMMARY: The Federal Aviation Administration (FAA) announces its findings on...

  6. Marriage/Family Issues and Wife Styles Across Naval Officer Career Stages: Their Implications for Career Success

    Science.gov (United States)

    1979-05-01

    Rapoport, Leisure and the Family Life Cycle (London: Routledge and Kegan Paul, 1975). Rapoport, R., R. Rapoport and J. Bumstead, eds., Working Couples (New...Street doston, KA 02210 Psychologist Office o! Naval Research Branch Office 1030 East Green Street P’asad’na, CA 9110b Head, Hanpower Training and...Office 536 S. Clark St. Chicago, IL 60605 DirectorI 1030 E. Green St. Pasadena, CA 91106 Sam L. Renneker Ot4R Resident Representative Georgia Institute of

  7. 77 FR 17105 - Identification of Interstate Motor Vehicles: City of Chicago, IL Registration Emblem Requirement...

    Science.gov (United States)

    2012-03-23

    ... section 31704; (2) Under the International Fuel Tax Agreement under section 31705 or under an applicable... through the International Fuel Tax Agreement; (3) Under a State law regarding motor vehicle license plates... Chicago Ground Transportation Tax is preempted by Federal law. Federal law prohibits States and their...

  8. Prevalence and covariates of food insecurity among residents of single-room occupancy housing in Chicago, IL, USA.

    Science.gov (United States)

    Bowen, Elizabeth A; Bowen, Sarah K; Barman-Adhikari, Anamika

    2016-04-01

    Emerging evidence suggests that food insecurity is a significant public health concern among people who are homeless or marginally housed. The present study assessed prevalence of food insecurity and its covariates among a group of marginally housed individuals living in single-room occupancy (SRO) dwellings, a population for which there is little extant health or nutrition research. Cross-sectional survey incorporating the Household Food Insecurity Access Scale. Ten private SRO residences in the Uptown neighbourhood of Chicago, IL, USA, 2013. SRO residents over 18 years of age who were able to communicate verbally in English (n 153). Food insecurity was widespread among SRO residents, with 75 % of the sample considered food insecure and 52 % meeting criteria for severe food insecurity. Bivariate analyses indicated that female gender, eating most meals at a soup kitchen, having a mental health condition, problem drinking, having at least one chronic health condition, and diabetes were all significantly associated with food insecurity. In the multivariate ordered logistic regression model, eating most meals at a soup kitchen remained as the only significant correlate of food insecurity (OR=10·13). SRO residents and other marginally housed populations face unique food access challenges. Although targeted assistance in the form of food stamps and congregate meal programmes remains critical, efforts to prevent and address food insecurity among homeless and marginally housed individuals should include policy interventions that recognize poverty as the root cause of food insecurity and aim to increase overall income and improve housing conditions.

  9. Structural Assessment of Knowledge and Skill

    Science.gov (United States)

    1992-08-01

    Street San Diego, CA 92152-6800 Chicago, IL 60616 Dr. Menucha Birenbaum Educational Testing Serv. Library, Code 231 Dr. Lorraine 0. Eyde Princeton, NJ...University Dr. Norman Frederiksen Educational Testing Service Rosedale Road Department of Psychology Educational Testing Service Princeton, NJ 08541... Psychology Educational Testing Service Arlington, VA 22207 Carnegie-Mellon University Princeton, NJ 08541 5000 Forbes Avenue Dr. Delwyn Harnisch Pittsburgh

  10. Chicago's urban forest ecosystem: results of the Chicago Urban Forest Climate Project

    Science.gov (United States)

    Gregory E. McPherson; David J. Nowak; Rowan A. Rowntree

    1994-01-01

    Results of the 3-year Chicago Urban Forest Climate Project indicate that there are an estimated 50.8 million trees in the Chicago area of Cook and DuPage Counties; 66 percent of these trees rated in good or excellent condition. During 1991, trees in the Chicago area removed an estimated 6,145 tons of air pollutants, providing air cleansing valued at $9.2 million...

  11. Street outreach with no streets.

    Science.gov (United States)

    Self, Bruce; Peters, Heather

    2005-01-01

    A street nurse position in the rural and small-town interior of British Columbia has been addressing the needs of street-involved or otherwise marginalized client populations by bringing healthcare services to wherever those clients are, rather than waiting for the clients to seek care. The primary reason for a street outreach approach is that marginalized populations face a variety of barriers to accessing traditional healthcare services--barriers such as homelessness, mental health problems, criminal involvement, lack of transportation, lack of ability to pay for prescriptions, lack of specialized or knowledgeable providers and provider discrimination. In the rural street nurse program, the target population includes the usual street nurse populations of illegal drug users and sex trade workers, which are more hidden in small communities than in larger urban centres, creating the community denial that is a barrier to healthcare access. Yet another barrier is the co-locaton of services common in small communities, where public health clinics might share a building with police services, making marginalized clients reluctant to attend clinics. The rural street nurse collaborates with public health nurses and other care providers (mental health workers, social workers, etc) with collegial advice and support, making and receiving referrals, and generally assisting one another--the street nurse through his rapport with the marginalized individuals and the others with their specialized knowledge. Rural street services are delivered whereverthe clientsfeel comfortable: a school, a drop-in centre, a mall, a youth centre or simplythe street. Services provided include sexually transmitted infection testing, chlamydia treatments, pregnancy testing emergency contraception pills and assistance with filling out forms for financial support. Accordingly, the street nurse's truck is equipped as a mobile treatment centre and office, with a cellphone and a stock of testing and

  12. Teaching about City Life in Chicago.

    Science.gov (United States)

    LaBianco, Claudine R.

    These materials discuss the history of Chicago, Illinois, including prominent persons in the city's past, and landmarks for which Chicago is well known. A number of activities are suggested, some of which concern Chicago's industries, historical sites, architecture, newspapers, ethnic groups, and history. A list of books about Chicago for…

  13. Atmospheric Mercury Transport Across Southern Lake Michigan: Influence from the Chicago/Gary Urban Area

    Science.gov (United States)

    Gratz, L. E.; Keeler, G. J.; Dvonch, J. T.

    2008-12-01

    The local and regional impacts of mercury emissions from major urban and industrial areas are critical to quantify in order to further understand mercury cycling in the environment. The Chicago/Gary urban area is one such location in which mercury emissions from industrial sources are significant and regional mercury transport needs to be further examined. Speciated atmospheric mercury was measured in Chicago, IL and Holland, MI from July to November 2007 to better characterize the impact of Chicago/Gary on southwest Michigan. Previous work under the 1994-1995 Lake Michigan Mass Balance Study (LMMBS) indicated that the highest levels of mercury deposition in southwest Michigan occurred with transport from the Chicago/Gary area, particularly with rapid transport where less mercury was deposited close to sources(1). However, at that time it was not possible to measure reactive gas phase mercury (RGM), a highly-soluble form of mercury in industrial emissions that is readily removed from the atmosphere. Since the LMMBS, the development of speciated mercury systems has made it possible to continuously monitor gaseous elemental mercury (Hg0), particulate mercury (HgP), and RGM. These measurements are useful for understanding atmospheric mercury chemistry and differentiating between local and regional source impacts due to the different behaviors of reactive and elemental mercury. Results from 2007 show that, on average, Hg0 and HgP were 1.5 times higher and RGM was 2 times higher in Chicago than in Holland. Mean mercury wet deposition was nearly 3 times higher in Chicago than in Holland. Meteorological analysis indicates that transport across the lake from Chicago/Gary occurred frequently during the study. Additional measurements of O3, SO2, meteorological parameters, event mercury and trace element precipitation samples, and modeled back-trajectories are used to discern regional transport events from local deposition and characterize the impact of the Chicago/Gary urban

  14. Developing a Data Visualization System for the Bank of America Chicago Marathon (Chicago, Illinois USA).

    Science.gov (United States)

    Hanken, Taylor; Young, Sam; Smilowitz, Karen; Chiampas, George; Waskowski, David

    2016-10-01

    As one of the largest marathons worldwide, the Bank of America Chicago Marathon (BACCM; Chicago, Illinois USA) accumulates high volumes of data. Race organizers and engaged agencies need the ability to access specific data in real-time. This report details a data visualization system designed for the Chicago Marathon and establishes key principles for event management data visualization. The data visualization system allows for efficient data communication among the organizing agencies of Chicago endurance events. Agencies can observe the progress of the race throughout the day and obtain needed information, such as the number and location of runners on the course and current weather conditions. Implementation of the system can reduce time-consuming, face-to-face interactions between involved agencies by having key data streams in one location, streamlining communications with the purpose of improving race logistics, as well as medical preparedness and response. Hanken T , Young S , Smilowitz K , Chiampas G , Waskowski D . Developing a data visualization system for the Bank of America Chicago Marathon (Chicago, Illinois USA). Prehosp Disaster Med. 2016;31(5):572-577.

  15. Tackling Absenteeism in Chicago

    Science.gov (United States)

    Allensworth, Elaine; Evans, Shayne

    2016-01-01

    Incisive research from the University of Chicago Urban Education Institute on the prevalence and consequences of absenteeism in Chicago schools has highlighted the dramatic effects of even moderate amounts of absences on grades, graduation rates, and student success in college. These insights spurred not only an ambitious 98% attendance goal on…

  16. 33 CFR 165.923 - Regulated Navigation Area between mile markers 296.1 and 296.7 of the Chicago Sanitary and Ship...

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Regulated Navigation Area between mile markers 296.1 and 296.7 of the Chicago Sanitary and Ship Canal located near Romeoville, IL. 165.923 Section 165.923 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED...

  17. Street children

    Directory of Open Access Journals (Sweden)

    Rončević Nevenka

    2013-01-01

    Full Text Available According to UNICEF, street child is any child under the age of 18 for whom the street has become home and/or source of income and which is not adequately protected or supervised by adult, responsible person. It has been estimated that there are between 100 and 150 million street children worldwide. Life and work on the street have long term and far-reaching consequences for development and health of these children. By living and working in the street, these children face the highest level of risk. Street children more often suffer from the acute illness, injuries, infection, especially gastrointestinal, acute respiratory infections and sexually transmitted diseases, inadequate nutrition, mental disorders, and drug abuse. They are more often victims of abuse, sexual exploitation, trafficking; they have higher rate of adolescent pregnancy than their peers from poor families. Street children and youth have higher rates of hospitalization and longer hospital stay due to seriousness of illness and delayed health care. Street children/youth are reluctant to seek health care, and when they try, they face many barriers. Street children are invisible to the state and their number in Serbia is unknown. Recently, some non­governmental organizations from Belgrade, Novi Sad and Nis have recognized this problem and tried to offer some help to street children, by opening drop­in centers, but this is not enough. To solve this problem, an engagement of the state and the whole community is necessary, and primary responsibility lies in health, social and educational sector. The best interests of the child must serve as a basic guideline in all activities aimed at improving health, quality of life and rights of children involved in the life and work in the street.

  18. Early history of cosmic rays at Chicago

    Science.gov (United States)

    Yodh, Gaurang B.

    2013-02-01

    Cosmic ray studies at the University of Chicago were started by Arthur Compton during the late 1920s. The high points of cosmic ray studies at Chicago under Compton and Marcel Schein are the focus of this report, which summarizes the research done at Chicago up to the end of World War II.

  19. Urban streets

    NARCIS (Netherlands)

    Schönfeld, von Kim Carlotta; Bertolini, Luca

    2017-01-01

    Today's urban streets are usually planned for purposes of mobility: pedestrians, as well as a variety of vehicles such as cars, trucks, and sometimes bicycles, are usually factored into an urban street plan. However, urban streets are also increasingly recognized as public spaces, accommodating

  20. 33 CFR 110.83 - Chicago Harbor, Ill.

    Science.gov (United States)

    2010-07-01

    .... Beginning at a point 2,120 feet South of the intersection of the North line of the Chicago Yacht Club... the first described line, passing 100 feet East of the Chicago Yacht Club bulkhead, 440 feet; thence.... Beginning at a point 145 feet North of the North line of the Chicago Yacht Club bulkhead, as constructed in...

  1. 46th Street pilot street lighting project.

    Science.gov (United States)

    2013-01-01

    Street lighting improvements provide an opportunity for governments to save money and to reduce their : environmental footprint. New energy-efficient technologies are being perfected that are more efficient than : standard high-pressure sodium street...

  2. 77 FR 24233 - Actuarial Advisory Committee With Respect to the Railroad Retirement Account; Notice of Public...

    Science.gov (United States)

    2012-04-23

    ... Actuary of the U.S. Railroad Retirement Board, 844 North Rush Street, Chicago, Illinois, on the conduct of... Actuary, U.S. Railroad Retirement Board, 844 North Rush Street, Chicago, Illinois 60611-2092. Dated: April...

  3. John Dewey and early Chicago functionalism.

    Science.gov (United States)

    Backe, A

    2001-11-01

    John Dewey and James Angell are regarded respectively as the founder and systematizer of the Chicago school of functional psychology. The early Chicago school traditionally has been portrayed as a unified theoretical approach based primarily on William James's naturalist theory of mental processes. It is argued in this article that although the psychology systematized by Angell bore a close affinity to James's naturalism, Dewey's own psychology was based primarily on the neo-Hegelian philosophy of Thomas Hill Green. Through a review of a number of Dewey's major writings, Green's neo-Hegelian philosophy is shown to have influenced Dewey's views on psychological concepts such as reaction, emotion, and perception during the formative period of the Chicago school. The interpretation of Dewey's psychology developed in this article leads to the conclusion that early Chicago functionalism should not be regarded as a unified theoretical approach.

  4. [Sharing and distrusting: street merchants' view of children in street situations].

    Science.gov (United States)

    Sánchez-Suárez, Diana M; Giraldo-Puerta, Alexandra; Giraldo-Pineda, Álvaro; Forero-Pulido, Constanza

    2016-06-01

    Objective To understand the meanings, through the description of experiences that street merchants have of their interactions with children in a street situation in downtown of Medellin in 2013. Methodology Qualitative investigation with ethnographic approach. Observations were made in the zone at different times of the day. Twelve interviews with street merchants were held in their work places. Records were kept in a field journal. Results The street merchants and children in street situations share the same space. Both groups try to survive and their relationship is mediated by the trust-distrust that is established between them. The coexistence generates ambivalent feelings. For the street merchants, children in street situations are the result of abandonment by the family, the state and society. They live in a hard world in which they are exposed to a series of risks that they must face. Conclusion The interaction between street merchants and children in street situations is good to the extent that conflicts are avoided, establishing norms of coexistence. The element that determines this relationship is trust-distrust. In trust, strong affective ties are generated, considering each other family. Distrust generates a preventative attitude.

  5. 78 FR 21537 - Drawbridge Operation Regulations; Upper Mississippi River, Rock Island, IL

    Science.gov (United States)

    2013-04-11

    ... Operation Regulations; Upper Mississippi River, Rock Island, IL AGENCY: Coast Guard, DHS. ACTION: Notice of... operating schedule that governs the Rock Island Railroad and Highway Drawbridge across the Upper Mississippi River, mile 482.9, at Rock Island, Illinois. The deviation is necessary to allow the Front Street 5K Run...

  6. Chicago-St. Louis high speed rail plan

    International Nuclear Information System (INIS)

    Stead, M.E.

    1994-01-01

    The Illinois Department of Transportation (IDOT), in cooperation with Amtrak, undertook the Chicago-St. Louis High Speed Rail Financial and Implementation Plan study in order to develop a realistic and achievable blueprint for implementation of high speed rail in the Chicago-St. Louis corridor. This report presents a summary of the Price Waterhouse Project Team's analysis and the Financial and Implementation Plan for implementing high speed rail service in the Chicago-St. Louis corridor

  7. Chicago-St. Louis high speed rail plan

    Energy Technology Data Exchange (ETDEWEB)

    Stead, M.E.

    1994-12-31

    The Illinois Department of Transportation (IDOT), in cooperation with Amtrak, undertook the Chicago-St. Louis High Speed Rail Financial and Implementation Plan study in order to develop a realistic and achievable blueprint for implementation of high speed rail in the Chicago-St. Louis corridor. This report presents a summary of the Price Waterhouse Project Team`s analysis and the Financial and Implementation Plan for implementing high speed rail service in the Chicago-St. Louis corridor.

  8. The Berlin tradition in Chicago: Franz Alexander and the Chicago Institute for Psychoanalysis.

    Science.gov (United States)

    Schmidt, Erika S

    2010-01-01

    Freud considered Franz Alexander, the first graduate of the Berlin Psychoanalytic Institute and an assistant in the Berlin Polyclinic, to be "one of our strongest hopes for the future." Alexander went on to become the first director of the Chicago Institute for Psychoanalysis in 1932 and modeled some of the Chicago Institute's mission on his Berlin experiences. He was also a researcher in psychosomatic medicine, a prolific writer about psychoanalysis and prominent in psychoanalytic organizations. As he proposed modifications in psychoanalytic technique, he became a controversial figure, especially in the elaboration of his ideas about brief therapy and the corrective emotional experience. This paper puts Alexander's achievements in historical context, draws connections between the Berlin and Chicago Institutes and suggests that, despite his quarrels with traditional psychoanalysis, Alexander's legacy may be in his attitude towards psychoanalysis, characterized by a commitment to scientific study, a willingness to experiment, and a conviction about the role of psychoanalysis within the larger culture.

  9. Street as Public Space - Measuring Street Life of Kuala Lumpur

    Science.gov (United States)

    Sulaiman, Normah; Ayu Abdullah, Yusfida; Hamdan, Hazlina

    2017-10-01

    Kuala Lumpur has envisioning in becoming World Class City by the year 2020. Essential elements of form and function of the urban environment are streets. Streets showcase the community and connect people. It’s one of the most comfortable social environment that provides aesthetical and interaction pleasure for everyone. Classified as main shopping streets in the local Kuala Lumpur urban design guidelines, Jalan Masjid India (JMI) has its uniqueness of shopping experience and social interaction. This conceptual paper will study the physical and cultural characteristics of the street that will generate the street character by mapping its original characters. The findings will focus on strengthening the methodology applied to promote improvements in evaluating it as a great public space. Results will also contribute to understanding the overall site context, the street connectivity, and urban dynamics. This paper is part of a larger study that addresses on transforming the sociability of public space.

  10. Simple street tree sampling

    Science.gov (United States)

    David J. Nowak; Jeffrey T. Walton; James Baldwin; Jerry. Bond

    2015-01-01

    Information on street trees is critical for management of this important resource. Sampling of street tree populations provides an efficient means to obtain street tree population information. Long-term repeat measures of street tree samples supply additional information on street tree changes and can be used to report damages from catastrophic events. Analyses of...

  11. Violence in the Street, Violence of the Street

    DEFF Research Database (Denmark)

    Heinskou, Marie Bruvik; Liebst, Lasse Suonperä

    While in his early and general theory of interaction rituals Randall Collins emphasised that social situations are both ’symbolic’ and ’material’, the latter dimension is largely absent from Collins’ theory of violence(Collins 2004; 1993: 214). Compared with criminology’s more recent situational...... studies of violence, it is noticeable that the analytical success of these studies is closely linked with understanding street violence as a spatial-situational phenomenon (Clarke 1997; Eck & Weisburd 1995; Bragand & Weisburd; 2010; Wikström et al. 2012; Sampson et al. 1997). In light of evidence...... for the spatial concentration of street violence, this paper takes its point of departure in a large study of Street Violence among youth in Copenhagen, Denmark (combining quantitative data from filed police reports (N = 501), data from CCTV (N=100) and qualitative analysis of selected cases of street violence...

  12. Chicago's Dearborn Observatory: a study in survival

    Science.gov (United States)

    Bartky, Ian R.

    2000-12-01

    The Dearborn Observatory, located on the Old University of Chicago campus from 1863 until 1888, was America's most promising astronomical facility when it was founded. Established by the Chicago Astronomical Society and directed by one of the country's most gifted astronomers, it boasted the largest telescope in the world and virtually unlimited operating funds. The Great Chicago Fire of 1871 destroyed its funding and demolished its research programme. Only via the sale of time signals and the heroic efforts of two amateur astronomers did the Dearborn Observatory survive.

  13. Genetic characterization of interleukins (IL-1α, IL-1β, IL-2, IL-4, IL-8, IL-10, IL-12A, IL-12B, IL-15 and IL-18) with relevant biological roles in lagomorphs

    Science.gov (United States)

    Neves, Fabiana; Abrantes, Joana; Almeida, Tereza; de Matos, Ana Lemos; Costa, Paulo P

    2015-01-01

    ILs, as essential innate immune modulators, are involved in an array of biological processes. In the European rabbit (Oryctolagus cuniculus) IL-1α, IL-1β, IL-2, IL-4, IL-8, IL-10, IL-12A, IL-12B, IL-15 and IL-18 have been implicated in inflammatory processes and in the immune response against rabbit hemorrhagic disease virus and myxoma virus infections. In this study we characterized these ILs in six Lagomorpha species (European rabbit, pygmy rabbit, two cottontail rabbit species, European brown hare and American pika). Overall, these ILs are conserved between lagomorphs, including in their exon/intron structure. Most differences were observed between leporids and American pika. Indeed, when comparing both, some relevant differences were observed in American pika, such as the location of the stop codon in IL-1α and IL-2, the existence of a different transcript in IL8 and the number of cysteine residues in IL-1β. Changes at N-glycosylation motifs were also detected in IL-1, IL-10, IL-12B and IL-15. IL-1α is the protein that presents the highest evolutionary distances, which is in contrast to IL-12A where the distances between lagomorphs are the lowest. For all these ILs, sequences of human and European rabbit are more closely related than between human and mouse or European rabbit and mouse. PMID:26395994

  14. Creating a marketplace for green roofs in Chicago

    International Nuclear Information System (INIS)

    Vitt Sale, L.; Berkshire, M.

    2004-01-01

    Since 2003, the Chicago Department of Planning and Development has been encouraging city developers to consider installing green roofs on buildings in Chicago, with the belief that this practice results in mitigation of the urban heat island effect, cleaner runoff leaving green roofs, sound attenuation, aesthetic value, oxygen production, and mitigation of carbon dioxide emissions. However, the benefits to developers, which include reduced stormwater runoff, extended roof life and energy savings, in total do not offset the first cost premium of a green roof. Despite this, and with no mandate requiring green roofs, the marketplace is growing. After seeing green roofs on a tour in Europe, the mayor of Chicago encouraged the first design and installation of a 20,300 square foot demonstration green roof in Chicago, and other city-sponsored pilot projects followed shortly after. Since then, the number of green roofs in Chicago has grown to over one million square feet. A map of Chicago showing locations of most of the projects was presented. It was suggested that lower prices for green roofs, higher energy costs and an inclination to invest in long-term strategies would accelerate the market. In an effort to engage the public in dialogue, the Department of Planning and Development held seminars to promote the benefits of green roofs . Participants had many questions about the applicability of green roofs to Chicago, expressing skepticism that Chicago's climate would provide the same benefits as in Europe. Other concerns were expressed regarding the devaluation of property values resulting from placing green roofs on buildings; doubts about roof leaks; maintenance practices; and, bugs and mold. Since the first cost premium of the system remains a question, most participants expressed interest in some kind of incentive program, but remained open-minded if benefits could be proved. 6 figs

  15. Creating a marketplace for green roofs in Chicago

    Energy Technology Data Exchange (ETDEWEB)

    Vitt Sale, L. [Wright and Co. Chicago, IL (United States); Berkshire, M. [City of Chicago, IL (United States)

    2004-07-01

    Since 2003, the Chicago Department of Planning and Development has been encouraging city developers to consider installing green roofs on buildings in Chicago, with the belief that this practice results in mitigation of the urban heat island effect, cleaner runoff leaving green roofs, sound attenuation, aesthetic value, oxygen production, and mitigation of carbon dioxide emissions. However, the benefits to developers, which include reduced stormwater runoff, extended roof life and energy savings, in total do not offset the first cost premium of a green roof. Despite this, and with no mandate requiring green roofs, the marketplace is growing. After seeing green roofs on a tour in Europe, the mayor of Chicago encouraged the first design and installation of a 20,300 square foot demonstration green roof in Chicago, and other city-sponsored pilot projects followed shortly after. Since then, the number of green roofs in Chicago has grown to over one million square feet. A map of Chicago showing locations of most of the projects was presented. It was suggested that lower prices for green roofs, higher energy costs and an inclination to invest in long-term strategies would accelerate the market. In an effort to engage the public in dialogue, the Department of Planning and Development held seminars to promote the benefits of green roofs . Participants had many questions about the applicability of green roofs to Chicago, expressing skepticism that Chicago's climate would provide the same benefits as in Europe. Other concerns were expressed regarding the devaluation of property values resulting from placing green roofs on buildings; doubts about roof leaks; maintenance practices; and, bugs and mold. Since the first cost premium of the system remains a question, most participants expressed interest in some kind of incentive program, but remained open-minded if benefits could be proved. 6 figs.

  16. Land of California?: The ambiguities of sweet home Chicago.

    Science.gov (United States)

    Kimsey, John

    2005-01-01

    This essay examines some historical questions and cultural constructions surrounding the song Sweet Home Chicago and its composer Robert Johnson. Noting that while the song has enjoyed long life, Johnson's lyric (describing Chicago as a land of California) has not, the essay critiques primitivist readings of Johnson while posing an African American cultural myth-Chicago as promised land of the Great Migration-as the subtext of his puzzling line. Finally, it considers whether mundane-sounding revisions of Johnson's lyric indicate a reduction in Chicago's mythic status, from safe haven to same old place.

  17. Safety of street: The role of street design

    Science.gov (United States)

    Rashid, Suhaila Abdul; Wahab, Mohammad Hussaini; Rani, Wan Nurul Mardiah Wan Mohd.; Ismail, Syuhaida

    2017-10-01

    Living in the cities poses many challenges for the vulnerable group of user especially women where they are exposed to many issues related to safety. With the changing of lifestyle and demands, women are expected to play multiple roles in the society and working is one of the tasks. When women are expected to be working as men do, they are no longer occupied at one place. Women nowadays travel on a daily basis and being in the streets is one of the important activities. With the influx of diverse group of people into the country, our streets are dominated by different types of people from different background. Due to these factors, there are possibilities of challenges and threats for users especially women. Therefore, city spaces especially the street become an important public realm for women. The design of the street should be able to make women feel safe as these are the public space where they spend time getting to and from work. The way women perceived their environment might be different from men especially when they fear of crime. Perception of safety will affect the quality of life where fear is an important psychological factor in human life. Living in fear will restrict human's freedom. Therefore, this study aimed to explore women's perception of safety in the streets of Kuala Lumpur. The study adopted a mixed-method approach of qualitative and quantitative in order to understand the safety perception among women that will later establish the relationship between built environment and human psychology. 120 respondents were selected randomly around Jalan Benteng, Jalan Tun Perak, Jalan Melaka and Jalan Melayu. Questionnaire survey forms were distributed and structured observation was conducted at interval period at these streets to examined and assess women's behavior. Finding shows that fear does affect women's perception and physical design of the streets are important in affecting their behavior.

  18. Chicago exploration days

    International Nuclear Information System (INIS)

    Zeitler, Elmar

    2012-01-01

    Single heavy atoms supported on thin carbon film were first imaged by Crewe, Wall and Langmore with their dark-field STEM. This glimpse into a hitherto invisible world we owe undeniably to Crewe's vision and determination, and to his gift to electrify, engage and encourage talented students. Since this successful event happened during my sabbatical stay in Crewe's group, the editors of this memorial volume asked me to write an account of its early history, which I gladly composed mostly from memory. The circumstances that led to my collaboration with Albert Crew in Chicago are reviewed, and the main project that we jointly embarked on the Chicago 1 MeV STEM is described. It is shown that the project was nearing completion and would have likely been successful, had funding been continued. The paper concludes with a tribute to Albert I wrote many years ago. -- Highlights: ►► Reasons and motivations for Crewe's interest in electron microscopy are reviewed. ► Reasons and motivations for Crewe's interest in electron microscopy are reviewed. ► Early theoretical work on STEM imaging is summarized. The design of the Chicago 1 MeV Scanning Transmission Electron Microscope is described. ► Construction details are illustrated. Reasons for the project not reaching a successful conclusion are given. ► Tribute is paid to Albert Crewe.

  19. Medline Plus

    Full Text Available ... of Chicago Medical Center, Chicago, IL, 6/26/2014) Aortic Aneurysm Hybrid Arch Debranching (University of Maryland ... of Chicago Medical Center, Chicago, IL, 6/26/2014) Heart Diseases Transesophageal Echocardiogram (TEE) (Shawnee Mission Medical ...

  20. Medline Plus

    Full Text Available ... Intervention (University of Chicago Medical Center, Chicago, IL, 6/26/2014) Aortic Aneurysm Hybrid Arch Debranching (University ... Intervention (University of Chicago Medical Center, Chicago, IL, 6/26/2014) Heart Diseases Transesophageal Echocardiogram (TEE) (Shawnee ...

  1. POLICY EVALUATION OF RESTRUCTURING STREET VENDORS IN SURAKARTA CITY (Study of Street Vendors in Monument Park Banjarsari and Street Vendors in Manahan Stadium

    Directory of Open Access Journals (Sweden)

    Frahlevi Prajasari

    2015-08-01

    Full Text Available This study examined the policy evaluation of restructuring street vendors in Surakarta city. Street vendors represent the economic actors in the informal sector of urban economic activity. The government of City/District usually removes these street vendors by disguising this activity behind the reason of structuring, . The study used descriptive research with a qualitative approach. The relocation of street vendors in Surakarta City is orderly and smooth without violence which may impact badly on physic and material because the government of Surakarta City, especially Surakarta Mayor, uses persuasive approach. Notoharjo Market is a relocation place for street vendors at Banjarsari Monument Park. In the beginning, Notoharjo Market is crowded with buyers but current days, street vendors who occupy Notoharjo Market complain about lack of buyers. The lack of buyers at Notoharjo Market is because the facilities previously provided by the government of Surakarta City are not well maintained. The government of Surakarta City must listening all complains of street vendors for the smoothness and orderliness of trading activity of street vendors. Not only listening, but the government of Surakarta City also gives appropriate and best solution to street vendors such that street vendors feel comfort in selling and their income is better than before.

  2. Street Children and Employment Opportunities

    International Nuclear Information System (INIS)

    Enos, H.N.; Njoka, M.

    1999-01-01

    Although there is a general realization that there are 'people' in the streets, we often take the phenomenon for granted probably because we wake up and go home only to come to the streets the following morning and still find the people. This situation is however changing with the emergence of 'birth' and increase of street children as we begin to take into consideration the category of people to be routinely found on the streets. The phrase 'street children' refer to the children below the statutory adult age living on or found on the streets. These children derive their livelihood from the streets. While the children on the streets may have a 'home' to go to, the latter are an integral part of the street having nowhere to retire to at the end of the day. The street children live in abject poverty and are exposed to many risks. They suffer from malnutrition and deficiency diseases due to low and poor nutrition intake. The street girls get trapped in teenage prostitution quite early in life. Of concern are the issues related to the working street children. Many street children engage in collecting and selling waste paper, bottles and plastics. They are referred to as 'chokora' because of their work of turning garbage upside down as they look for something useful. Unfortunately they have to sell these wastes to powerful forces including people who underpay and harrass them

  3. Chicago exploration days

    Energy Technology Data Exchange (ETDEWEB)

    Zeitler, Elmar, E-mail: zr@fhi-berlin.mpg.de [Fritz-Haber-Institut der Max-Planck-Gesellschaft Faradayweg 4-6 D-1000 Berlin 33 (Dahlem) (Germany)

    2012-12-15

    Single heavy atoms supported on thin carbon film were first imaged by Crewe, Wall and Langmore with their dark-field STEM. This glimpse into a hitherto invisible world we owe undeniably to Crewe's vision and determination, and to his gift to electrify, engage and encourage talented students. Since this successful event happened during my sabbatical stay in Crewe's group, the editors of this memorial volume asked me to write an account of its early history, which I gladly composed mostly from memory. The circumstances that led to my collaboration with Albert Crew in Chicago are reviewed, and the main project that we jointly embarked on the Chicago 1 MeV STEM is described. It is shown that the project was nearing completion and would have likely been successful, had funding been continued. The paper concludes with a tribute to Albert I wrote many years ago. -- Highlights: Black-Right-Pointing-Pointer Black-Right-Pointing-Pointer Reasons and motivations for Crewe's interest in electron microscopy are reviewed. Black-Right-Pointing-Pointer Reasons and motivations for Crewe's interest in electron microscopy are reviewed. Black-Right-Pointing-Pointer Early theoretical work on STEM imaging is summarized. The design of the Chicago 1 MeV Scanning Transmission Electron Microscope is described. Black-Right-Pointing-Pointer Construction details are illustrated. Reasons for the project not reaching a successful conclusion are given. Black-Right-Pointing-Pointer Tribute is paid to Albert Crewe.

  4. The Economic Outlook and the Role of Credit Intermediation

    OpenAIRE

    Evans, Charles L.

    2008-01-01

    Remarks by Charles L. Evans, President and Chief Executive Officer,Federal Reserve Bank of Chicago Chartered Financial Analysts Society of Chicago Lunch Mid-America Club 200 East Randolph Street Chicago, Illinois

  5. Street children and political violence: a socio-demographic analysis of street children in Rwanda.

    Science.gov (United States)

    Veale, Angela; Donà, Giorgia

    2003-03-01

    The aims were: (1) to examine the profile of African street children and to assess the link between street children in Africa and political violence; (2) to undertake a systematic examination of causal factors of street children in postgenocide Rwanda; and (3) to situate this analysis in the context of the socio-cultural and political impact of the genocide on Rwandan communities. Observational mapping examined the profile and activities of Rwandan street children. Structured interviews were carried out with 290 children in four regional towns to obtain information on socio-demographic, familial, educational background, causal factors surrounding street life involvement, psychological well-being, and relationship to the street. Focus group discussions and key informant interviews examined the relationship between street children and the broader Rwandan society. Street children in Rwanda were predominantly adolescent boys, almost half of whom were homeless (42%), with a high proportion of orphaned children or children who had lost at least one parent. Two variables predicted homelessness: child's guardian and reason for being in street. Qualitative accounts of children conveyed the impact of death of family members, repatriation, imprisonment of parents, and poverty on their lives. The analysis highlighted the need for community based support for children in alternative guardianship care and for policies to support the reintegration of male youths in postconflict welfare strategies as prevention strategies for street migration.

  6. Alternative Fuels Data Center: City of Chicago Program Encourages Petroleum

    Science.gov (United States)

    lacked the funds to support such a project, but officials worked with the Chicago Area Clean Cities (CACC networking opportunities. This photo shows a parked compressed natural gas van the City of Chicago's fleet Infrastructure: 11 private E85 fueling stations Related Links Ethanol Natural Gas Chicago Area Clean Cities

  7. Adolescent Hopefulness in Tanzania: Street Youth, Former Street Youth, and School Youth

    Science.gov (United States)

    Nalkur, Priya G.

    2009-01-01

    This study compares hope in street youth, former street youth, and school youth (aged 12-18) in Tanzania. Responding to Snyder's hope theory, the author argues that not only personal agency but also the stability of living context (street, shelter, home) shapes hopefulness. Employing qualitative and quantitative analyses, the author presents a…

  8. A Mobilization Planning Study: Leadtimes for Movement of Army Plant Equipment to Mobilization Producers

    Science.gov (United States)

    1979-04-01

    dimension) ,.,’.: or overweight (exceeding .,’.:’.;■■.’. ’.’\\ ■■’:■ 80,000 lbs). (Dunensions and weight of commodities referred to are for exclusive...508 Lebanon, IN 488 Chicago, IL 487 Bellwood, IL 487 Chicago, IL 487 Peru , IL • 448 New Brighton, MN 428 New Brighton, MN 428 Rock Island...MK Eau Claire, WI Antigo, WI Rock Island, IL Peru , IL Chicago, IL DISTANCE 720 miles 657 512 DISTANCE I45O 1|29 DISIAa’CE 532 532

  9. Chicago-metoden

    DEFF Research Database (Denmark)

    Kurrild-Klitgaard, Peter

    2010-01-01

    nærmeste medarbejder, stabschef Rahm Emmanuel, har begge trådt deres politiske børnesko i det rå miljø i Demokraternes Chicago, hvor korruption og politiske trusler hører til hverdagen for alle, der når toppen. I en tid, hvor der næsten ugentligt afsløres nye skandaler, og hvor Obama stik imod sine...

  10. Streets? Where We're Going, We Don't Need Streets

    Science.gov (United States)

    Bailey, J.

    2017-12-01

    In 2007 Google Street View started as a project to provide 360-degree imagery along streets, but in the decade since has evolved into a platform through which to explore everywhere from the slope of everest, to the middle of the Amazon rainforest to under the ocean. As camera technology has evolved it has also become a tool for ground truthing maps, and provided scientific observations, storytelling and education. The Google Street View "special collects" team has undertaken increasingly more challenging projects across 80+ countries and every continent. All of which culminated in possibly the most ambitious collection yet, the capture of Street View on board the International Space Station. Learn about the preparation and obstacles behind this and other special collects. Explore these datasets through both Google Earth and Google Expeditions VR, an educational tool to take students on virtual field trips using 360 degree imagery.

  11. Thermal Comfort Assessment in The Open Space in Bandung Case Study Dago Street and Riau Street

    Science.gov (United States)

    Sugangga, M.; Janesonia, K. I.; Illiyin, D. F.; Donny Koerniawan, M.

    2018-05-01

    Bandung’s temperature has been higher since last years. This phenomenon affects the level of thermal comfort in open space. One indicator that determines the thermal comfort level is the type of activity performed by the open space user. Riau Street and Dago Street are corridors that are often used by the people for strolling, jogging, shopping. Dago Street has special event every Sunday namely car free day. Both corridors have different orientation; Dago Street is North to South corridor while Riau Street’s is West to East. The goal of the study is to compare people’s perception of thermal comfort in both corridors. This research uses two methods, namely qualitative method and quantitative method. Based on the results of qualitative analysis found that the thermal conditions in Dago Street more comfortable than the Riau Street. The result of quantitative analysis found that the average PET (thermal comfort indices) value of Dago Street was at 27.5 °C PET and Riau Street 28.6 °C PET. Dago Street is considered more convenient because it has a lower PET value than Riau Street. The people perception of thermal comfort is very important to start the steps for designing the orientation of street in urban design.

  12. Potential reductions of street solids and phosphorus in urban watersheds from street cleaning, Cambridge, Massachusetts, 2009-11

    Science.gov (United States)

    Sorenson, Jason R.

    2013-01-01

    Material accumulating and washing off urban street surfaces and ultimately into stormwater drainage systems represents a substantial nonpoint source of solids, phosphorus, and other constituent loading to waterways in urban areas. Cost and lack of usable space limit the type and number of structural stormwater source controls available to municipalities and other public managers. Non-structural source controls such as street cleaning are commonly used by cities and towns for construction, maintenance and aesthetics, and may reduce contaminant loading to waterways. Effectiveness of street cleaning is highly variable and potential improvements to water quality are not fully understood. In 2009, the U.S. Geological Survey, in cooperation with the Massachusetts Department of Environmental Protection, the U.S. Environmental Protection Agency, and the city of Cambridge, Massachusetts, and initiated a study to better understand the physical and chemical nature of the organic and inorganic solid material on street surfaces, evaluate the performance of a street cleaner at removing street solids, and make use of the Source Loading and Management Model (SLAMM) to estimate potential reductions in solid and phosphorus loading to the lower Charles River from various street-cleaning technologies and frequencies. Average yield of material on streets collected between May and December 2010, was determined to be about 740 pounds per curb-mile on streets in multifamily land use and about 522 pounds per curb-mile on commercial land-use streets. At the end-of-winter in March 2011, about 2,609 and 4,788 pounds per curb-mile on average were collected from streets in multifamily and commercial land-use types, respectively. About 86 percent of the total street-solid yield from multifamily and commercial land-use streets was greater than or equal to 0.125 millimeters in diameter (or very fine sand). Observations of street-solid distribution across the entire street width indicated that as

  13. Wall Street som kreationistisk forkynder

    DEFF Research Database (Denmark)

    Ekman, Susanne

    2016-01-01

    Artiklen gennemgår Karen Hos etnografi om Wall Street: "Liquidated: An ethnography of Wall Street" set i lyset af den offentlige debat vedrørende Goldman Sachs opkøb af Dong......Artiklen gennemgår Karen Hos etnografi om Wall Street: "Liquidated: An ethnography of Wall Street" set i lyset af den offentlige debat vedrørende Goldman Sachs opkøb af Dong...

  14. Chicago arhitektuuribiennaal / Eve Komp

    Index Scriptorium Estoniae

    Komp, Eve, 1982-

    2015-01-01

    Chicagos esimest korda korraldatud arhitektuuribiennaali nimi oli "The State of the Art of Architecture", mis toimus 03. oktoober 2015.a. - 03. jaanuar 2016.a. Biennaali eesmärk oli pakkuda rahvusvahelist arhitektuurisündmust kohalikule arhitektuurikogukonnale.

  15. School Violent Crime and Academic Achievement in Chicago.

    Science.gov (United States)

    Burdick-Will, Julia

    2013-10-01

    Educational outcomes vary dramatically across schools in the United States. Many under-performing schools, especially in Chicago, also deal with high levels of violent crime on school grounds. Exposure to this type of frequent violence may be an important factor shaping already disadvantaged students' educational experiences. However, estimating the effect of school violence on learning is difficult due to potential selection bias and the confounding of other school-level problems. Using detailed crime data from the Chicago Police Department, complete administrative records from the Chicago Public Schools, and school climate surveys conducted by the Consortium on Chicago School Research (2002-10), this study exploits variation in violent crime rates within schools over time to estimate its effect on academic achievement. School and neighborhood fixed-effects models show that violent crime rates have a negative effect on test scores, but not on grades. This effect is more likely related to direct reductions in learning, through cognitive stress and classroom disruptions, than changes in perceived safety, general school climate, or discipline practices.

  16. RACE, CODE OF THE STREET, AND VIOLENT DELINQUENCY: A MULTILEVEL INVESTIGATION OF NEIGHBORHOOD STREET CULTURE AND INDIVIDUAL NORMS OF VIOLENCE*

    Science.gov (United States)

    Stewart, Eric A.; Simons, Ronald L.

    2011-01-01

    The study outlined in this article drew on Elijah Anderson’s (1999) code of the street perspective to examine the impact of neighborhood street culture on violent delinquency. Using data from more than 700 African American adolescents, we examined 1) whether neighborhood street culture predicts adolescent violence above and beyond an adolescent’s own street code values and 2) whether neighborhood street culture moderates individual-level street code values on adolescent violence. Consistent with Anderson’s hypotheses, neighborhood street culture significantly predicts violent delinquency independent of individual-level street code effects. Additionally, neighborhood street culture moderates individual-level street code values on violence in neighborhoods where the street culture is widespread. In particular, the effect of street code values on violence is enhanced in neighborhoods where the street culture is endorsed widely. PMID:21666759

  17. Chicago's urban forest ecosystem: Results of the Chicago Urban Forest Climate Project. (Includes executive summary). Forest Service general technical report (Final)

    International Nuclear Information System (INIS)

    McPherson, E.G.; Nowak, D.J.; Rowntree, R.A.

    1994-06-01

    Results of the 3-year Chicago Urban Forest Climate Project indicate that there are an estimated 50.8 million trees in the Chicago area of Cook and DuPage Counties; 66 percent of these trees rated in good or excellent condition. During 1991, trees in the Chicago area removed an estimated 6,145 tons of air pollutants, providing air cleansing valued at $9.2 million dollars. These trees also sequester approximately 155,000 tons of carbon per year, and provide residential heating and cooling energy savings that, in turn, reduce carbon emissions from power plants by about 12,600 tons annually. Shade, lower summer air temperatures, and a reduction in windspeed associated with increasing tree cover by 10 percent can lower total heating and cooling energy use by 5 to 10 percent annually ($50 to $90 per dwelling unit). The projected net present value of investment in planting and care of 95,000 trees in Chicago is $38 million ($402 per planted tree), indicating that the long-term benefits of trees are more than twice their costs

  18. Changing industrial patterns in the metroplitan Chicago area

    Energy Technology Data Exchange (ETDEWEB)

    Allardice, D.

    1994-12-31

    The industrial base of Chicago, and most Midwestern cities, continues to change. These changes are particularly visible in the manufacturing sector where the exodus of companies has left behind abandoned factories and industrial sites that now blight the urban landscape. As urban centers have seen a steady decline in their ability to attract and maintain their manufacturing base, great interest has been placed in seeing what can be done to attract economic activity back into the urban center. For most Midwestern cities, this often means trying to either replace or stem the tide of manufacturing facilities that have left the city for {open_quotes}greenfields{close_quotes} in suburban or rural locations or have simply moved overseas. On the replacement front, to compensate for the loss of manufacturing, some cities such as Chicago have managed to expand other areas of their economies, such as business services, finance, and tourism and recreation to maintain their vitality. This paper discusses three aspects of the changing economic landscape of Chicago and other Midwestern urban areas. First, some historical perspective will be provided on how Chicago came to be a manufacturing center and what factors since World War II have led manufacturing facilities to move away from the urban center. Second, the future prospects for manufacturing in the central city will be examined. Finally, what policies may help increase (or at the very least maintain) the concentration of manufacturing in Chicago will be discussed.

  19. Changing industrial patterns in the metroplitan Chicago area

    International Nuclear Information System (INIS)

    Allardice, D.

    1994-01-01

    The industrial base of Chicago, and most Midwestern cities, continues to change. These changes are particularly visible in the manufacturing sector where the exodus of companies has left behind abandoned factories and industrial sites that now blight the urban landscape. As urban centers have seen a steady decline in their ability to attract and maintain their manufacturing base, great interest has been placed in seeing what can be done to attract economic activity back into the urban center. For most Midwestern cities, this often means trying to either replace or stem the tide of manufacturing facilities that have left the city for open-quotes greenfieldsclose quotes in suburban or rural locations or have simply moved overseas. On the replacement front, to compensate for the loss of manufacturing, some cities such as Chicago have managed to expand other areas of their economies, such as business services, finance, and tourism and recreation to maintain their vitality. This paper discusses three aspects of the changing economic landscape of Chicago and other Midwestern urban areas. First, some historical perspective will be provided on how Chicago came to be a manufacturing center and what factors since World War II have led manufacturing facilities to move away from the urban center. Second, the future prospects for manufacturing in the central city will be examined. Finally, what policies may help increase (or at the very least maintain) the concentration of manufacturing in Chicago will be discussed

  20. Simulating the impacts of on-street vehicle parking on traffic operations on urban streets using cellular automation

    Science.gov (United States)

    Chen, Jingxu; Li, Zhibin; Jiang, Hang; Zhu, Senlai; Wang, Wei

    2017-02-01

    In recent years, many bicycle lanes on urban streets are replaced with vehicle parking places. Spaces for bicycle riding are reduced, resulting in changes in bicycle and vehicle operational features. The objective of this study is to estimate the impacts of on-street parking on heterogeneous traffic operation on urban streets. A cellular automaton (CA) model is developed and calibrated to simulate bicycle lane-changing on streets with on-street parking. Two types of street segments with different bicycle lane width are considered. From the simulation, two types of conflicts between bicycles and vehicles are identified which are frictional conflicts and blocking conflicts. Factors affecting the frequency of conflicts are also identified. Based on the results, vehicle delay is estimated for various traffic situations considering the range of occupancy levels for on-street parking. Later, a numerical network example is analyzed to estimate the network impact of on-street parking on traffic assignment and operation. Findings of the study are helpful to policies and design regarding on-street vehicle parking to improve the efficiency of traffic operations.

  1. Street-art

    OpenAIRE

    Rybnikářová, Klára

    2009-01-01

    This thesis is concerned with the street-art and graffiti phenomenon. The theoretical research is focused on presenting the essence and character of this art style, while also watching it from socio-cultural point of view and observing it in context of art history. The theoretical study is followed by the didactical part of thesis, where I present possibilities of using the street-art theme in art education programs in the school setting. My thesis is concluded with a discussion of a practica...

  2. Citygml and the Streets of New York - a Proposal for Detailed Street Space Modelling

    Science.gov (United States)

    Beil, C.; Kolbe, T. H.

    2017-10-01

    Three-dimensional semantic city models are increasingly used for the analysis of large urban areas. Until now the focus has mostly been on buildings. Nonetheless many applications could also benefit from detailed models of public street space for further analysis. However, there are only few guidelines for representing roads within city models. Therefore, related standards dealing with street modelling are examined and discussed. Nearly all street representations are based on linear abstractions. However, there are many use cases that require or would benefit from the detailed geometrical and semantic representation of street space. A variety of potential applications for detailed street space models are presented. Subsequently, based on related standards as well as on user requirements, a concept for a CityGML-compliant representation of street space in multiple levels of detail is developed. In the course of this process, the CityGML Transportation model of the currently valid OGC standard CityGML2.0 is examined to discover possibilities for further developments. Moreover, a number of improvements are presented. Finally, based on open data sources, the proposed concept is implemented within a semantic 3D city model of New York City generating a detailed 3D street space model for the entire city. As a result, 11 thematic classes, such as roadbeds, sidewalks or traffic islands are generated and enriched with a large number of thematic attributes.

  3. Street Children as M arginal People: The Relationship between Life History and Social Networks on the Street

    OpenAIRE

    SUCHARITKUL, Juthathip

    2007-01-01

    This paper assumes that street children are victims of socioeconomic development policy. As a consequence of the street life experience, children are labeled as street children by society and their way of their life is different from ordinary children, thus pushing them to become marginalized people. The purpose of this paper is to examine the Street Children phenomenon, and especially to study the relationship between their life history and personal networks on the street. The focus is to...

  4. MAPCERN links to Google Street View

    CERN Multimedia

    Matilda Heron

    2015-01-01

    CERN’s online maps, MAPCERN, now have the added bonus of Google Street View, thanks to the new release of images of many CERN sites captured by Google.   New Street View images of CERN sites have been added to MAPCERN, see bottom-right-hand image in the screenshot above.   Google Street View, an integrated service of Google Maps introduced in 2007, links 360-degree panoramic photos into a virtual tour. CERN and Google began collaborating on this Street View project in 2010 and now these Street View images have been embedded into MAPCERN, accessible by clicking the “Street View” tab in MAPCERN’s bottom-right-hand window. If you need to locate a building at CERN, or plan an operation on some equipment, you can save time by using the Street View images to check out the area in advance. The CERN Meyrin site has been fully mapped, as well as the surfaces of the eight LHC points, BA2 and BA3. New Street View images of CERN, including the Pr...

  5. Urban trees and forests of the Chicago region

    Science.gov (United States)

    David J. Nowak; Robert E. III Hoehn; Allison R. Bodine; Daniel E. Crane; John F. Dwyer; Veta Bonnewell; Gary Watson

    2013-01-01

    An analysis of trees in the Chicago region of Illinois reveals that this area has about 157,142,000 trees with tree and shrub canopy that covers 21.0 percent of the region. The most common tree species are European buckthorn, green ash, boxelder, black cherry, and American elm. Trees in the Chicago region currently store about 16.9 million tons of carbon (61.9 million...

  6. Allegheny County Street Centerlines

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset contains the locations of the street centerlines for vehicular and foot traffic in Allegheny County. Street Centerlines are classified as Primary Road,...

  7. Street Politics

    Directory of Open Access Journals (Sweden)

    Michael J. Shapiro

    2012-03-01

    Full Text Available I write from Prague, where, unlike in most urban formations, the main city street plays an iconic role; it references a history of political protest. However, before elaborating on the protest iconography of the Prague street, Vaclavske nam, I want to locate the ways in which the design of urban space is actualized in everyday life in the cities of the world. Three functions stand out; the first involves dwelling, the second seeing, and the third moving. With respect to the first function – dwelling – the design partitions and coordinates residential, commercial and leisure functions. At times these are organized to segregate different classes (Robert Moses’ redesign of much of New York stands out with respect to the segregation function. With respect to the second function – seeing – the design of urban space is allegiance-inspiring; it involves sight lines that afford urban dwellers and visitors views of iconic buildings and statues, which reference key founding moments in the past and/or authoritative political functions in the present (Here, L’Enfants design for Washington DC stands out as exemplary. Its manifest intention was to make the buildings housing executive, legislative and judicial functions visible from many vantage points. Rarely are the streets themselves iconic. Their dominant role is involved with the effectuation of movement. As for this third function: As Lewis Mumford famously points out, streets were once part of an asterisk design, radiating out from an exemplary, often spiritual center...

  8. Road and Street Centerlines, Street-The data set is a line feature consisting of 13948 line segments representing streets. It was created to maintain the location of city and county based streets., Published in 1989, Davis County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Road and Street Centerlines dataset current as of 1989. Street-The data set is a line feature consisting of 13948 line segments representing streets. It was created...

  9. 78 FR 13378 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-02-27

    ... Monastery, 5700 N. Harlem Dr., Chicago, 13000048 Storkline Furniture Corporation Factory, 4400-4418 W. 26th St., Chicago, 13000049 MASSACHUSETTS Essex County North Street Fire Station, 142 North St., Salem...

  10. Mean Streets: An analysis on street level pollution in NYC

    Science.gov (United States)

    Parker, G.

    2017-12-01

    The overarching objective of this study is to quantify the spatial and temporal variability in particulatematter concentration (PM 2.5) along crowded streets in New York City. Due to their fine size and lowdensity PM 2.5 stays longer in the atmosphere and could bypass human nose and throat and penetratedeep in to the lungs and even enter the circulatory system. PM 2.5 is a by-product of automobilecombustion and is a primary cause of respiratory malfunction in NYC. The study would monitor streetlevel concentration of PM2.5 across three different routes that witness significant pedestrian traffic;observations will be conducted along these three routes at different time periods. The study will use theAirBeam community air quality monitor. The monitor tracks PM 2.5 concentration along with GPS, airtemperature and relative humidity. The surface level concentration monitored by AirBeam will becompared with atmospheric concentration of PM 2.5 that are monitored at the NOAA CREST facility onCCNY campus. The lower atmospheric values will be correlated with street level values to assess thevalidity of using of lower atmospheric values to predict street level concentrations. The street levelconcentration will be compared to the air quality forecasted by the New York Department ofEnvironment Conservation to estimate its accuracy and applicability.

  11. Street art - vandalismus nebo umění?

    OpenAIRE

    Grabmüllerová, Eva

    2012-01-01

    The diploma thesis ‚Street Art - Vandalism or Art?' deals with a world-wide phenomenon of contemporary art. The thesis focuses on the characterization of street art and history of street art (its origin and development) and analyzes the difference between street art and graffiti. The thesis presents street art techniques as well as notable street artists. The thesis also observes street art scene in the Czech Republic and depicts features that street art has in common with other art movements...

  12. Personal and Familial Properties of Street Children--"Street Children: The Forgotten or Not Remembered Ones"

    Science.gov (United States)

    Özbas, Mehmet

    2015-01-01

    With this research it is aimed to determine the personal traits of Street Children depending on them and also the socio-economic variables of Street Children resulting from their families. For this main aim in the research process, it is provided to have communication directly with the parents of Street Children using one-to-one and face-to-face…

  13. The social world of street children : street children's peer friendship, group life and subculture in Addis Ababa, Ethiopia

    OpenAIRE

    Fikre, Kaleab

    2016-01-01

    This study attempts to explore the street children’s social world, focusing on their peer friendship, group life, and street subculture in Addis Ababa, Ethiopia. The study shows how street children’s peer friendship, street group, and subculture are part and parcel of children’s quest for survival in the street in the absence of guardians conventionally considered as responsible for the provision and protection of children. The main perspective of the study is grounded in the p...

  14. COMMON GROUNDS BETWEEN PRINTMAKING AND STREET ART

    Directory of Open Access Journals (Sweden)

    Burcak Balamber

    2016-09-01

    Full Text Available Graffiti movement, born as a result of an effort of the youth, who felt themselves socially excluded and alone, to show their existence and identities during the 1960s, expanded its scope owing to street based artists such as Keith Haring and Jean-Michel Basquiat entering to the galleries, and transformed into an artistic manner of expression having aesthetic concerns by adopting a more inclusive definition ‘street art’. During this transformation of street art,street artists experimented with various methods from many different disciplines and hence created works in a wide range of varieties in terms of plastic and artistic values. Among these disciplines, printmakinghastaken its own place in street artas a discipline thatdeeply influenced street artists.Printmaking has fascinated street artists and become a part of their production process, not only with its philosophy sharing common grounds with street art and advantages in terms of its tecnical practices but also its unique plastic and linear values.Thanks to the opportunities of printmaking, street art has succeeded creating a tremendous impression worldwide, and even positioned itself into today’s greatest museums/gallery halls. This article aims to show how and in what way printmaking has influenced street art being in a transformation since the 1960s, and to put an emphasis on theimportance of printmaking on today’s street art.

  15. Intelligent street lighting clustering

    NARCIS (Netherlands)

    Verhoeven, R.; Jovanovic, N.; Lukkien, J.J.

    2014-01-01

    The advances in dynamic street lighting introduce new functionality for control and maintenance of the street lighting infrastructure. Vital elements in this infrastructure are the powerful controlling devices that control separate groups of light poles and collect information from the system. For

  16. 75 FR 1621 - Change in Bank Control Notices; Acquisition of Shares of Bank or Bank Holding Companies

    Science.gov (United States)

    2010-01-12

    ..., 2010. A. Federal Reserve Bank of Chicago (Colette A. Fried, Assistant Vice President) 230 South LaSalle Street, Chicago, Illinois 60690-1414: 1. John E. Helgerson, Ottumwa, Iowa; to acquire additional shares...

  17. Treatment of Active Tuberculosis in Chicago, 2008-2011: The Role of Public Health Departments.

    Directory of Open Access Journals (Sweden)

    Reid Fletcher

    Full Text Available Evaluate differences in TB outcomes among different provider types in Chicago, IL.We retrospectively reviewed all TB cases reported to the Chicago Department of Public Health (CDPH from 2008 through 2011. Provider type was stratified into three groups: public, public-private, and private providers. Multivariate regression was used to evaluate treatment duration and time to sputum culture conversion. A Cox proportional hazard model was used to assess treatment completion.Of 703 cases, 203 (28.9%, 314 (44.7%, and 186 (26.5% were treated by public, public-private and private providers, respectively. Adjusted regression showed private provider patients had a 48-day (95% CI 22.0-74.3 increase in treatment duration and a 30-day (95% C.I. 9.5-51.1 increase in time to sputum culture conversion. Cox model showed increased risk of remaining on treatment was associated with extra-pulmonary TB (aHR 0.78, 95% C.I. 0.62-0.98, being foreign-born (aHR 0.74, 95% C.I. 0.58-0.95, and any drug resistance (aHR 0.59, 95% C.I. 0.46-0.76. There were no differences in outcomes between public and public-private providers.Patients treated solely in the private sector had prolonged time to sputum culture conversion and treatment duration which lead to increased cost for treatment, prolonged infectiousness, potential for transmission, and the possibility for increased medication side effects.

  18. StreetMekka - Ledelse af Københavns nye streetkulturhus

    OpenAIRE

    Gjelstrup, Mikkel

    2009-01-01

    Street culture is spreading out through the streets of Denmark and in the summer of 2009 the City of Copenhagen will open up an indoor street culture facility called StreetMekka. Moving street culture from its natural concrete habitat to a communal facility presents challenges. The City of Copenhagen has made official guideline for the StreetMekka facility to follow, but the free and self organized street culture is not an easy thing to keep within guidelines. This master thesis discusses fro...

  19. Road and Street Centerlines, StreetLabels-The data set is a text feature consisting of 6329 label points representing street names. It was created to show the names of city and county based streets., Published in 1989, Davis County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Road and Street Centerlines dataset current as of 1989. StreetLabels-The data set is a text feature consisting of 6329 label points representing street names. It was...

  20. Road and Street Centerlines - COUNTY_STREET_CENTERLINES_IDHS_IN: Street Centerlines Maintained by County Agencies in Indiana (Indiana Department of Homeland Security, Line Shapefile)

    Data.gov (United States)

    NSGIC State | GIS Inventory — COUNTY_STREET_CENTERLINES_IDHS_IN is a line feature class that contains street centerlines maintained by county agencies in Indiana, provided by personnel of Indiana...

  1. 76 FR 16388 - Fees for Reviews of the Rule Enforcement Programs of Contract Markets and Registered Futures...

    Science.gov (United States)

    2011-03-23

    ... Chicago Climate Futures Exchange 21,705 0.0205 10,853 US Futures Exchange 0 0.0001 0 OneChicago 1,157 0... 62,449 (30,420) 32,029 HedgeStreet 14,375 8 14,383 Chicago Climate Futures Exchange 12,259 7 12,266... 10,194 13 10,207 Chicago Climate Futures Exchange 8,306 3 8,309 US Futures Exchange 14,602 68 14,670...

  2. Partnering with diabetes educators to improve patient outcomes

    OpenAIRE

    Burke SD; Sherr D; Lipman RD

    2014-01-01

    Sandra D Burke,1,2 Dawn Sherr,3 Ruth D Lipman3 1American Association of Diabetes Educators, Chicago, IL, USA; 2University of Illinois at Chicago College of Nursing, Urbana, IL, USA; 3Science and Practice, American Association of Diabetes Educators, Chicago, IL, USA Abstract: Diabetes is a chronic, progressive disease that affects millions worldwide. The paradigm of diabetes management has shifted to focus on empowering the person with diabetes to manage the disease successfully and to improv...

  3. Do suburban residents want to pay for wide streets? a survey on consumer preference and ability to afford towards wide street and on-street parking in American suburbia.

    Science.gov (United States)

    2016-08-01

    All local governments in the U.S. set the street minimum width and cross-section design for local : neighborhood streets. Because local streets typically require no more than two traffic lanes (approx. 20 feet : wide), a minimum width of 26 feet or w...

  4. Chicago particle accelerator conference

    International Nuclear Information System (INIS)

    Southworth, Brian

    1989-01-01

    Naturally, emphasis at the Particle Accelerator Conference in Chicago in March was on work in the US, just as the newly instituted European Particle Accelerator Conference places emphasis on work in the 'old continent'. All will come together at the international conference in Japan in August. The proposed US Superconducting Supercollider (SSC) was highlighted in the opening talk at Chicago. Progress on this inchoate project to explore the TeV (1000 GeV) energy region by colliding 20 TeV proton beams was reported by the recently-appointed Director of the SSC Laboratory, Roy Schwitters. He reviewed the physics challenges and described progress and plans towards full authorization of construction.This year, the SSC conceptual design will be transformed into a 'site specific' report, now that the location at Waxahachie in Ellis County, Texas, has been selected. The Central Design Group, based in Berkeley for the past few years, will soon move to the Waxahachie region. The top management structure is taking shape and an International Advisory Committee is being formed

  5. Chicago particle accelerator conference

    Energy Technology Data Exchange (ETDEWEB)

    Southworth, Brian

    1989-06-15

    Naturally, emphasis at the Particle Accelerator Conference in Chicago in March was on work in the US, just as the newly instituted European Particle Accelerator Conference places emphasis on work in the 'old continent'. All will come together at the international conference in Japan in August. The proposed US Superconducting Supercollider (SSC) was highlighted in the opening talk at Chicago. Progress on this inchoate project to explore the TeV (1000 GeV) energy region by colliding 20 TeV proton beams was reported by the recently-appointed Director of the SSC Laboratory, Roy Schwitters. He reviewed the physics challenges and described progress and plans towards full authorization of construction.This year, the SSC conceptual design will be transformed into a 'site specific' report, now that the location at Waxahachie in Ellis County, Texas, has been selected. The Central Design Group, based in Berkeley for the past few years, will soon move to the Waxahachie region. The top management structure is taking shape and an International Advisory Committee is being formed.

  6. Street Lines, US, 2015, NAVTEQ

    Data.gov (United States)

    U.S. Environmental Protection Agency — NAVTEQ Streets for the United States. The Streets layer contains all roads plus all Road Network attributes such as direction of travel, lanes, dividers, speed...

  7. Street as Sustainable City Structural Element

    Science.gov (United States)

    Leyzerova, A. V.; Bagina, E. J.

    2017-11-01

    Sustainability in architecture is nowadays of particular significance in the course of globalization and information density. The technospehere spontaneous development poses a threat to the sustainability of traditional urban forms where a street is one of the essential forming elements in the urban structure. The article proposes to consider formally compositional street features in relation to one of the traditional streets in the historic center of Ekaterinburg. The study examines the street-planning structure, the development of its skeleton elements, silhouette and fabric elevation characteristics as well as the scale characteristics and visual complexity of objects. The study provided architectural and artistic aspects of street sustainability, and limits of the appropriate scale and composition consistency under which the compatibility of alternative compositional forms existing at different times is possible.

  8. Street Prostitution Zones and Crime

    OpenAIRE

    Bisschop, Paul; Kastoryano, Stephen; van der Klaauw, Bas

    2015-01-01

    This paper studies the effects of introducing legal street prostitution zones on both registered and perceived crime. We exploit a unique setting in the Netherlands where legal street prostitution zones were opened in nine cities under different regulation systems. We provide evidence that the opening of these zones was not in response to changes in crime. Our difference-in-difference analysis using data on the largest 25 Dutch cities between 1994 and 2011 shows that opening a legal street pr...

  9. IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice.

    Science.gov (United States)

    Kolumam, Ganesh; Wu, Xiumin; Lee, Wyne P; Hackney, Jason A; Zavala-Solorio, Jose; Gandham, Vineela; Danilenko, Dimitry M; Arora, Puneet; Wang, Xiaoting; Ouyang, Wenjun

    2017-01-01

    Diabetic foot ulcers (DFU) are one of the major complications in type II diabetes patients and can result in amputation and morbidity. Although multiple approaches are used clinically to help wound closure, many patients still lack adequate treatment. Here we show that IL-20 subfamily cytokines are upregulated during normal wound healing. While there is a redundant role for each individual cytokine in this subfamily in wound healing, mice deficient in IL-22R, the common receptor chain for IL-20, IL-22, and IL-24, display a significant delay in wound healing. Furthermore, IL-20, IL-22 and IL-24 are all able to promote wound healing in type II diabetic db/db mice. Mechanistically, when compared to other growth factors such as VEGF and PDGF that accelerate wound healing in this model, IL-22 uniquely induced genes involved in reepithelialization, tissue remodeling and innate host defense mechanisms from wounded skin. Interestingly, IL-22 treatment showed superior efficacy compared to PDGF or VEGF in an infectious diabetic wound model. Taken together, our data suggest that IL-20 subfamily cytokines, particularly IL-20, IL-22, and IL-24, might provide therapeutic benefit for patients with DFU.

  10. 40 CFR 81.14 - Metropolitan Chicago Interstate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... Quality Control Region. 81.14 Section 81.14 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.14 Metropolitan Chicago Interstate Air Quality Control Region. The Metropolitan Chicago Interstate Air Quality Control Region (Illinois-Indiana) is revised to consist of the...

  11. Medline Plus

    Full Text Available ... Medical Center, Chicago, IL, 6/26/2014) Heart Failure Surgical Ventricular Reconstruction (Montefiore Medical Center, New York, ... Medical Center, Chicago, IL, 6/26/2014) Heart Failure Surgical Ventricular Reconstruction (Montefiore Medical Center, New York, ...

  12. Cleaning up the Streets of Denver

    International Nuclear Information System (INIS)

    Stegen, R.L.; Wood, T.R.; Hackett, J.R.; Sogue, A.

    2006-01-01

    Between 1913 and 1924, several Denver area facilities extracted radium from carnotite ore mined from the Paradox basin region of Colorado. Tailings or abandoned ores from these facilities were apparently incorporated into asphalt used to pave approximately 7.2 kilometers (4.5 miles) of streets in Denver. A majority of the streets are located in residential areas. The radionuclides are bound within the asphalt matrix and pose minimal risk unless they are disturbed. The City and County of Denver (CCoD) is responsible for controlling repairs and maintenance on these impacted streets. Since 2002, the CCoD has embarked on a significant capital improvement project to remove the impacted asphalt for secure disposal followed by street reconstruction. To date, Parsons has removed approximately 55 percent of the impacted asphalt. This paper discusses the history of the Denver Radium Streets and summarizes on-going project efforts. (authors)

  13. Street level society

    DEFF Research Database (Denmark)

    Vinum, Christine; Nissen, Morten

    2006-01-01

    This paper aims to reflect on research findings from different empirical studies of social work with young drug users and socially excluded young people in Copenhagen. In the paper we account for historical changes in social policy and interventions into young people's drug taking in Copenhagen......, and partly from the decentralizing and specializing efforts characteristic of the Danish welfare state and its institutions. We discuss a general turn towards street level interventions to address the problems of social exclusion, as well as different attempts to create what we term street level heterotopias...

  14. Th-17 regulatory cytokines IL-21, IL-23, and IL-6 enhance neutrophil production of IL-17 cytokines during asthma.

    Science.gov (United States)

    Halwani, Rabih; Sultana, Asma; Vazquez-Tello, Alejandro; Jamhawi, Amer; Al-Masri, Abeer A; Al-Muhsen, Saleh

    2017-11-01

    In a subset of severe asthma patients, chronic airway inflammation is associated with infiltration of neutrophils, Th-17 cells and elevated expression of Th-17-derived cytokines (e.g., interleukin [IL]-17, IL-21, IL-22). Peripheral neutrophils from allergic asthmatics are known to express higher IL-17 cytokine levels than those from healthy subjects, but the regulatory mechanisms involved are not well understood. We hypothesize that Th-17 regulatory cytokines could modulate IL-17 expression in neutrophils. Peripheral blood neutrophils isolated from asthmatics were stimulated with IL-21, IL-23, and IL-6 cytokines and their ability to produce IL-17A and IL-17F was determined relative to healthy controls. Signal transducer and activator of transcription 3 (STAT3) phosphorylation levels were measured in stimulated neutrophil using flow cytometry. The requirement for STAT3 phosphorylation was determined by blocking its activation using a specific chemical inhibitor. Stimulating asthmatic neutrophils with IL-21, 23, and 6 enhanced the production of IL-17A and IL-17F at significantly higher levels comparatively to healthy controls. Stimulating neutrophils with IL-21, IL-23, and IL-6 cytokines enhanced STAT3 phosphorylation, in all cases. Interestingly, inhibiting STAT3 phosphorylation using a specific chemical inhibitor dramatically blocked the ability of neutrophils to produce IL-17, demonstrating that STAT3 activation is the major factor mediating IL-17 gene expression. These findings suggest that neutrophil infiltration in lungs of severe asthmatics may represent an important source of pro-inflammatory IL-17A and -F cytokines, a production enhanced by Th-17 regulatory cytokines, and thus providing a feedback mechanism that sustains inflammation. Our results suggest that STAT3 pathway could be a potential target for regulating neutrophilic inflammation during severe asthma.

  15. Hepatitis B Stigma and Knowledge among Vietnamese in Ho Chi Minh City and Chicago

    Directory of Open Access Journals (Sweden)

    Lan Dam

    2016-01-01

    Full Text Available Stigma regarding viral hepatitis and liver disease has psychological and social consequences including causing negative self-image, disrupting relationships, and providing a barrier to prevention, testing, and treatment. The aim of this study was to characterize and compare HBV knowledge and stigma in Vietnamese in Ho Chi Minh City and Chicago and to begin to evaluate the cultural context of HBV stigma. Methods. A written survey including knowledge questions and a validated HBV stigma questionnaire was distributed to Vietnamese in Ho Chi Minh City and Chicago. 842 surveys from Ho Chi Minh City and 170 from Chicago were analyzed. Results. Vietnamese living in Chicago had better understanding of HBV transmission and that HBV can cause chronic infection and liver cancer. Vietnamese in Chicago had higher stigma scores on a broad range of items including guilt and shame about HBV and were more likely to feel that persons with HBV can bring harm to others and should be isolated. Conclusions. Vietnamese in Ho Chi Minh City and Chicago have knowledge deficits about HBV, particularly regarding modes of transmission. Persons in Ho Chi Minh City expressed lower levels of HBV stigma than Vietnamese living in Chicago, likely reflecting changing cultural attitudes in Vietnam. Culturally appropriate educational initiatives are needed to address the problem of HBV stigma.

  16. 75 FR 67731 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2010-11-03

    ... November 16, 2010. A. Federal Reserve Bank of Chicago (Colette A. Fried, Assistant Vice President) 230 South LaSalle Street, Chicago, Illinois 60690-1414: 1. Robert John Dentel, Victor, Iowa, and Mary P...; 8:45 am] BILLING CODE 6210-01-P ...

  17. Air quality considerations for stormwater green street design.

    Science.gov (United States)

    Shaneyfelt, Kathryn M; Anderson, Andrew R; Kumar, Prashant; Hunt, William F

    2017-12-01

    Green streets are increasingly being used as a stormwater management strategy to mitigate stormwater runoff at its source while providing other environmental and societal benefits, including connecting pedestrians to the street. Simultaneously, human exposure to particulate matter from urban transportation is of major concern worldwide due to the proximity of pedestrians, drivers, and cyclists to the emission sources. Vegetation used for stormwater treatment can help designers limit the exposure of people to air pollutants. This goal can be achieved through the deliberate placement of green streets, along with strategic planting schemes that maximize pollutant dispersion. This communication presents general design considerations for green streets that combine stormwater management and air quality goals. There is currently limited guidance on designing green streets for air quality considerations; this is the first communication to offer suggestions and advice for the design of green stormwater streets in regards to their effects on air quality. Street characteristics including (1) the width to height ratio of the street to the buildings, (2) the type of trees and their location, and (3) any prevailing winds can have an impact on pollutant concentrations within the street and along sidewalks. Vegetation within stormwater control measures has the ability to reduce particulate matter concentrations; however, it must be carefully selected and placed within the green street to promote the dispersion of air flow. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Air quality considerations for stormwater green street design

    International Nuclear Information System (INIS)

    Shaneyfelt, Kathryn M.; Anderson, Andrew R.; Kumar, Prashant; Hunt, William F.

    2017-01-01

    Green streets are increasingly being used as a stormwater management strategy to mitigate stormwater runoff at its source while providing other environmental and societal benefits, including connecting pedestrians to the street. Simultaneously, human exposure to particulate matter from urban transportation is of major concern worldwide due to the proximity of pedestrians, drivers, and cyclists to the emission sources. Vegetation used for stormwater treatment can help designers limit the exposure of people to air pollutants. This goal can be achieved through the deliberate placement of green streets, along with strategic planting schemes that maximize pollutant dispersion. This communication presents general design considerations for green streets that combine stormwater management and air quality goals. There is currently limited guidance on designing green streets for air quality considerations; this is the first communication to offer suggestions and advice for the design of green stormwater streets in regards to their effects on air quality. Street characteristics including (1) the width to height ratio of the street to the buildings, (2) the type of trees and their location, and (3) any prevailing winds can have an impact on pollutant concentrations within the street and along sidewalks. Vegetation within stormwater control measures has the ability to reduce particulate matter concentrations; however, it must be carefully selected and placed within the green street to promote the dispersion of air flow. - Highlights: • Green streets can be used for both stormwater and air quality management. • Design considerations must be made to minimize human exposure to air pollutants. • Urban vegetation can improve air quality with careful selection and placement.

  19. IL-6/IL-12 Cytokine Receptor Shuffling of Extra- and Intracellular Domains Reveals Canonical STAT Activation via Synthetic IL-35 and IL-39 Signaling.

    Science.gov (United States)

    Floss, D M; Schönberg, M; Franke, M; Horstmeier, F C; Engelowski, E; Schneider, A; Rosenfeldt, E M; Scheller, J

    2017-11-09

    IL-35 and IL-39 are recently discovered shared members of the IL-6- and IL-12-type cytokine family with immune-suppressive capacity. IL-35 has been reported to induce the formation of four different receptor complexes: gp130:IL-12β2, gp130:gp130, IL-12β2:IL-12β2, and IL-12β2:WSX-1. IL-39 was proposed to form a gp130:IL-23R receptor complex. IL-35, but not IL-39, has been reported to activate non-conventional STAT signaling, depending on the receptor complex and target cell. Analyses of IL-35 and IL-39 are, however, hampered by the lack of biologically active recombinant IL-35 and IL-39 proteins. Therefore, we engineered chimeric cytokine receptors to accomplish synthetic IL-35 and IL- 39 signaling by shuffling the extra- and intracellular domains of IL-6/IL-12-type cytokine receptors, resulting in biological activity for all previously described IL-35 receptor complexes. Moreover, we found that the proposed IL-39 receptor complex is biologically active and discovered two additional biologically active synthetic receptor combinations, gp130/IL-12Rβ1 and IL-23R/IL-12Rβ2. Surprisingly, synthetic IL-35 activation led to more canonical STAT signaling of all receptor complexes. In summary, our receptor shuffling approach highlights an interchangeable, modular domain structure among IL-6- and IL-12-type cytokine receptors and enabled synthetic IL-35 and IL-39 signaling.

  20. Vecchia e nuova scuola di Chicago

    Directory of Open Access Journals (Sweden)

    G.S. TAVLAS

    1977-09-01

    Full Text Available This paper traces the evolvement of monetary-policy proposals at Chicago from the early 1930s up until the appearance of Friedman’s classic “Restatement” of the quantity theory in 1956. First, the pragmatic nature of Chicagoan monetary economics during the depression-dominated 1930s is examined. The emergence of the Chicagoan affirmation in the efficiency of traditional monetary policy is then described. It is argued that rather than representing a transmogrification of the monetary views of his predecessors, Friedman’s “Restatement” more accurately reflects a culmination of post-Keynesian Chicago contributions on money. In addition, the interpretation of budget deficits financed by money creation as the implementation of monetary, as opposed to fiscal, policy is shown to be a common link among Chicagoans throughout the entire period under consideration. JEL: E51, E52, E40

  1. Universal design characteristic on themed streets

    Science.gov (United States)

    Harsritanto, Bangun IR; Indriastjario; Wijayanti

    2017-12-01

    People around the world can access the streets to fulfil their daily activities regardless of their gender, age, and abilities. The streetscape is an urban public space which is built to facilitate the basic needs of people as social being. The themed street is an urban streetscape designed and built in detail with a theme or special purpose in an of urban development process. Universal design facilitates the full range of human diversity as physical appearance, perception, cognitive abilities, sizes, and shapes. By designing for the diversity, the specialized streets become more functional and user-friendly. The purpose of this study is to examine several design characteristics of themed streets in several countries from three different continents using universal design principles for giving proper directions to develop more user-friendly streets. Literature review and case study were used as research methods. The literature review was extracted and compiled from manuscripts, streetscape design books, and from universal design principles. Furthermore, the constructed theory were used to examine the case studies of themed streets. The findings indicated that themed streets’ character design were strongly influenced by local cultural aspect even though the basic guidelines were universal design principles; the resumed design direction can be suggested universal along with the richness of local aspects.

  2. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... established by Robert Hill and Thea Flaum. 737 N. Michigan Ave., Suite 1560 , Chicago, IL 60611. © 2011 – ... established by Robert Hill and Thea Flaum. 737 N. Michigan Ave., Suite 1560 , Chicago, IL 60611. © 2011 – ...

  3. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available ... established by Robert Hill and Thea Flaum. 737 N. Michigan Ave., Suite 1560 , Chicago, IL 60611. © 2011 – ... established by Robert Hill and Thea Flaum. 737 N. Michigan Ave., Suite 1560 , Chicago, IL 60611. © 2011 – ...

  4. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... established by Robert Hill and Thea Flaum. 737 N. Michigan Ave., Suite 1560 , Chicago, IL 60611. © 2011 – ... established by Robert Hill and Thea Flaum. 737 N. Michigan Ave., Suite 1560 , Chicago, IL 60611. © 2011 – ...

  5. Sex and Fertility After SCI

    Medline Plus

    Full Text Available ... established by Robert Hill and Thea Flaum. 737 N. Michigan Ave., Suite 1560 , Chicago, IL 60611. © 2011 – ... established by Robert Hill and Thea Flaum. 737 N. Michigan Ave., Suite 1560 , Chicago, IL 60611. © 2011 – ...

  6. The Regulation of Street Foods

    DEFF Research Database (Denmark)

    Forkour, John Boulard; Samuelsen, Helle; Yeboah, Eric Henry

    2017-01-01

    the challenges and negotiating strategies of regulators of street-vended foods in Ghana and analyses the implication for their relationship with street food vendors. The paper reveals that regulators operate in a context of limited resources, leading to a general feeling of neglect. In coping, regulators adopt...

  7. Street Papers, Work, and Begging

    DEFF Research Database (Denmark)

    Cockburn, Patrick Joseph

    2014-01-01

    Street papers are publications produced specifically for sale by the homeless and other vulnerable people in many countries around the world. Their social status is, however, often conspicuously unstable: ‘Get a job!’ has been reported as a common insult addressed to vendors, and street paper...

  8. Street Pastors : on security, care and faith

    NARCIS (Netherlands)

    van Steden, R.

    2018-01-01

    This paper presents a study of Street Pastors in Cardiff, the capital city of Wales. Street Pastors are Christian volunteers who look after vulnerable people in the night-time economy. In this manner, they provide ‘securitas’ through empathy and care. The motives of Street Pastors for engaging with

  9. High resolution esophageal manometry--the switch from "intuitive" visual interpretation to Chicago classification.

    Science.gov (United States)

    Srinivas, M; Balakumaran, T A; Palaniappan, S; Srinivasan, Vijaya; Batcha, M; Venkataraman, Jayanthi

    2014-03-01

    High resolution esophageal manometry (HREM) has been interpreted all along by visual interpretation of color plots until the recent introduction of Chicago classification which categorises HREM using objective measurements. It compares HREM diagnosis of esophageal motor disorders by visual interpretation and Chicago classification. Using software Trace 1.2v, 77 consecutive tracings diagnosed by visual interpretation were re-analyzed by Chicago classification and findings compared for concordance between the two systems of interpretation. Kappa agreement rate between the two observations was determined. There were 57 males (74 %) and cohort median age was 41 years (range: 14-83 years). Majority of the referrals were for gastroesophageal reflux disease, dysphagia and achalasia. By "intuitive" visual interpretation, the tracing were reported as normal in 45 (58.4 %), achalasia 14 (18.2 %), ineffective esophageal motility 3 (3.9 %), nutcracker esophagus 11 (14.3 %) and nonspecific motility changes 4 (5.2 %). By Chicago classification, there was 100 % agreement (Kappa 1) for achalasia (type 1: 9; type 2: 5) and ineffective esophageal motility ("failed peristalsis" on visual interpretation). Normal esophageal motility, nutcracker esophagus and nonspecific motility disorder on visual interpretation were reclassified as rapid contraction and esophagogastric junction (EGJ) outflow obstruction by Chicago classification. Chicago classification identified distinct clinical phenotypes including EGJ outflow obstruction not identified by visual interpretation. A significant number of unclassified HREM by visual interpretation were also classified by it.

  10. City Streets

    Data.gov (United States)

    Minnesota Department of Natural Resources — This data set contains roadway centerlines for city streets found on the USGS 1:24,000 mapping series. In some areas, these roadways are current through the 2000...

  11. Spatial Character Analysis of Streets as Public Spaces: The Case of Izmit Hurriyet and Cumhuriyet Street, Turkey

    Science.gov (United States)

    Özbayraktar, Mehtap; Pekdemir, Merve; Mırzaliyeva, Gumru

    2017-10-01

    The word “public” was first used to refer to the theatre audience in France in the mid-17th century. In the 18th century, it turned into the meaning of “public space incorporating a large variety of people and composed of acquaintances and strangers”. The concepts of publicity, public space, and public realm have been studied and described by many researchers in the course of time. These descriptions show the development of public space as well. In the very general sense, public spaces are areas of personal and social happiness; collective living spaces of the society; areas of expression of natural and cultural variety; and key elements providing a ground for the establishment of an identity. In the United Nations’ report on public spaces, public space is addressed under six groups: 1. The spaces we intensely used in our daily life; 2. Green open public spaces; 3. Public activity spaces which users can go in without any difficulty, are open to public, and are under protection; 4. Public sector realm (social agreements in which the people are represented, contribute to collective goods, and trust in the administrators elected); 5. City as a public space; 6. Cyberspace. As cities grow, public spaces transform and diversify. Attempts are made to meet the changing needs through types of space developed. However, the character of the existing public spaces, the distribution of open spaces and parks and their inadequacy, the destruction of public space, and the things that are required to be done stand as important issues to be addressed. One of the public spaces going through transformation are streets which we intensely use in our daily life. In general, streets are defined as roads with buildings on both sides in settlements such as provinces and districts whose boundaries are determined by neighbouring buildings. Some researchers have defined streets based on their social functions. According to them, streets are meeting spaces; spaces to deal with

  12. At University of Chicago, Dispute over Friedman Center Continues to Simmer

    Science.gov (United States)

    Glenn, David

    2008-01-01

    This article reports on the dispute about the creation of an institute named for the late economist and free-market advocate Milton Friedman at the University of Chicago. Five months after the University of Chicago announced plans to invest $200-million in an economics institute named for the late Milton Friedman, the project is still generating…

  13. PLC based Smart Street Lighting Control

    OpenAIRE

    D.V.Pushpa Latha; K.R.Sudha; Swati Devabhaktuni

    2013-01-01

    Conventional street lighting systems in most of the areas are Online at regular intervals of time irrespective of the seasonal variations. The street lights are simply switched on at afternoon and turned off in the morning. The consequence is that a large amount of Power is wasted meaninglessly. As energy consumption is an issue of increasing interest, possible energy savings in public street lighting systems are recently discussed from different viewpoints. The purpose of this work is to des...

  14. 24 CFR 3280.4 - Incorporation by reference.

    Science.gov (United States)

    2010-04-01

    ... AISC—American Institute of Steel Construction, One East Wacker Drive, Chicago, IL 60601 AISI—American..., Chicago, IL 60616 MIL—Military Specifications and Standards, Naval Publications and Forms Center, 5801...—National Fire Protection Association, Batterymarch Park, Quincy, MA 02269 NPA—National Particleboard...

  15. Vecchia e nuova scuola di Chicago

    Directory of Open Access Journals (Sweden)

    G.S. TAVLAS

    2014-03-01

    Full Text Available This paper traces the evolvement of monetary-policy proposals at Chicago from the early 1930s up until the appearance of Friedman’s classic “Restatement” of the quantity theory in 1956. First, the pragmatic nature of Chicagoan monetary economics during the depression-dominated 1930s is examined. The emergence of the Chicagoan affirmation in the efficiency of traditional monetary policy is then described. It is argued that rather than representing a transmogrification of the monetary views of his predecessors, Friedman’s “Restatement” more accurately reflects a culmination of post-Keynesian Chicago contributions on money. In addition, the interpretation of budget deficits financed by money creation as the implementation of monetary, as opposed to fiscal, policy is shown to be a common link among Chicagoans throughout the entire period under consideration. JEL: E51, E52, E40

  16. [Addictive behavior of street children: interculturation and resilience].

    Science.gov (United States)

    Kommegne, T; Denoux, P; Bernoussi, A; Njiengwe, E F

    2014-09-01

    This research belongs to a more comprehensive study on the care of street children in Cameroon. The idea is to develop an analysis of the street pathology where symptoms such as addictive behavior and drug addiction can be found. Beside HIV AIDS, addictive behaviors are the main risk factors that many professionals have to face with while dealing with the street problems today. Through an intercultural approach, we examined the practices of addictive typology, their initiatory role and their function in the integration of the street system. We also analysed their importance in the survival strategies. After an overview of theoretical controversies that feed the debate on addictions, we questioned the impact of these practices on the street career through the prism of general theory of addictions, particularly the hedonic management model. Addiction helps to resist adversity, it helps to desist and then to begin a harmonious neo development despite the horrors of the street experience. We undertook a quantitative and qualitative study on a sample of 148 street children. We proposed to 128 of them a questionnaire focused on addictive behaviors and survival strategies in the street context. We notably evaluated the street career of 24 of them, using interviews and standardized tests to assess self-esteem (Coopersmith's SEI) frustration tolerance (Rosenweig's P-F) and self-efficacy (Sherer's SE Scale) in order to measure the impact of addictive behaviors on the resilience process. We found that the street career is essentially traumatic, and that addictive behaviors involving various integration strategies are strongly linked to the interculturation process through the identity strategies and the intercultural competences. Addiction itself is not significantly related to self-esteem issues but strongly impacts on self-efficacy and the ability to tolerate frustration. They allow the street children to withstand the street adversity but are a real obstacle to their

  17. The street school Srikandi as an empowerment model of humane education for the street girls of non halfway house in Surabaya

    Science.gov (United States)

    Setyowati, RRN; Yani, MT; Imron, A.

    2018-01-01

    The street children have not had a solid emotional mental, however they must deal into the life of street that harsh, competitive and tend to affect negatively for their personality development. Their where abouts on the street is not motivated by family economic factor only, but it is also influenced by the disharmony of role and function of family rules and social environment influences. The street children empowerment that had been conducted by the halfway house does not run effectively. This research was aimed to identify problems faced by the street girls, to describe the efforts to overcome the problems faced by the street girls, and also developing the empowerment model for the street girls in Surabaya who do not stay in the halfway house. This research used qualitative method. The problems are often experienced by the street girls, for instance violence. Besides, imitative behavior arises as a respond towards behavior that happened to them. The parents also play role in the process of social control. The empowerment model that is designed is the educational empowerment through revitalization of family rules. Moreover, life skills education has to be strengthened to improve the welfare standard of living.

  18. Testing Under Fire: Chicago's Problem.

    Science.gov (United States)

    Byrd, Manford, Jr.

    The history and development of city-wide testing programs in Chicago since 1936 are reviewed and placed in context with the impact on testing of Sputnik and the passage of the National Defense Education Act of 1958. Current testing problems include the time lag between events and curricular changes and new test construction, the time lag between…

  19. Chicago, Illinois: The Windy City

    Science.gov (United States)

    McIntosh, Phyllis

    2008-01-01

    Once famous mainly for stockyards and steel mills, Chicago now boasts more top-rated five-star restaurants than any other city in the United States and has been voted by various publications as one of the "Top 10 U.S. Destinations," one of the "Best Walking Cities" in the United States, and one of the "Ten Best Places to…

  20. The Chicago classification of motility disorders: an update.

    Science.gov (United States)

    Roman, Sabine; Gyawali, C Prakash; Xiao, Yinglian; Pandolfino, John E; Kahrilas, Peter J

    2014-10-01

    The Chicago Classification defines esophageal motility disorders in high resolution manometry. This is based on individual scoring of 10 swallows performed in supine position. Disorders of esophago-gastric junction (EGJ) outflow obstruction are defined by a median integrated relaxation pressure above the limit of normal and divided into 3 achalasia subtypes and EGJ outflow obstruction. Major motility disorders (aperistalsis, distal esophageal spasm, and hypercontractile esophagus) are patterns not encountered in controls in the context of normal EGJ relaxation. Finally with the latest version of the Chicago Classification, only two minor motor disorders are considered: ineffective esophageal motility and fragmented peristalsis. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. The Education Rights of Street-Involved Children

    Directory of Open Access Journals (Sweden)

    Sonja Grover

    2010-05-01

    Full Text Available This paper provides an overview of certain key aspects of the practical and legal situation of street-involved children globally. The inadequate protection of these children under both domestic and international law is addressed. The diversity of the population of street-involved children is considered as is the fact that this group is composed of both legally stateless and de facto stateless children. The relationship of street involvement to child labor, various health risks and victimization is discussed. The educational needs of older street-involved children are addressed including their right to participate in decision-making regarding aspects of educational service design and delivery. The overall objective of this paper is to encourage those who are involved in, or could impact upon educational policy to include street-involved children in their educational planning implementation and advocacy efforts.

  2. Edificio de viviendas. Lake Meadows Chicago

    Directory of Open Access Journals (Sweden)

    Skidmore - Owings y Merrill, Arquitectos

    1958-09-01

    Full Text Available "Lake Meadows" es una amplia parcela, de cuatrocientos mil metros cuadrados, situada en las afueras de Chicago, con vistas dominantes sobre el lago Michigan. En tan bello emplazamiento se ha construido uno de los más atractivos conjuntos residenciales norteamericanos.

  3. Modelling traffic pollution in streets

    Energy Technology Data Exchange (ETDEWEB)

    Berkowicz, R.; Hertel, O. [National Environmental Research Inst., Dept. of Atmospheric Environment, Roskilde (Denmark); Larsen, S.E.; Soerensen, N.N.; Nielsen, M. [Risoe National Lab., Dept. of Meteorology and Wind Energy, Roskilde (Denmark)

    1997-01-01

    This report concerns mainly the subject related to modelling air pollution from traffic in urban streets. A short overview is presented over the theoretical aspects and examples of most commonly used methods and models are given. Flow and dispersion conditions in street canyons are discussed and the presentation is substantiated with the analysis of the experimental data. The main emphasis is on the modelling methods that are suitable for routine applications and a more detailed presentation is given of the Operational Street Pollution Model (OSPM), which was developed by the National Environmental Research Institute. The model is used for surveillance of air pollution from traffic in Danish cities and also for special air pollution studies. (au) 76 refs.

  4. Smart street lighting : The advantages of LED street lighting and a smart control system in Uppsala municipality

    OpenAIRE

    Sjöberg, Inga; Gidén Hember, Amanda; Wallerström, Carolina

    2017-01-01

    The purpose of this bachelor thesis is to examine how LED street lights and a smart street light control system can reduce the energy consumption, costs and in extension the CO2 equivalents in a geographically delimited area. In 2015 the municipality of Sala installed LED armatures connected to a smart control system in the whole municipality. The smart control system enables for instance adjustment of the light intensity at specific times during the day and a supervision of the street light ...

  5. IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans

    DEFF Research Database (Denmark)

    Steensberg, Adam; Fischer, Christian Philip; Keller, Charlotte

    2003-01-01

    compared with saline infusion. In addition, C-reactive protein increased 3 h post-rhIL-6 infusion and was further elevated 16 h later compared with saline infusion. rhIL-6 induced increased levels of plasma cortisol and, consequently, an increase in circulating neutrophils and a decrease in the lymphocyte......-alpha, enhances the levels not only of IL-1ra but also of IL-10. Furthermore, IL-6 induces an increase in cortisol and, consequently, in neutrocytosis and late lymphopenia to the same magnitude and with the same kinetics as during exercise, suggesting that muscle-derived IL-6 has a central role in exercise...

  6. The 9th International Countercurrent Chromatography Conference held at Dominican University, Chicago, USA, August 1-3, 2016.

    Science.gov (United States)

    Friesen, J Brent; McAlpine, James B; Chen, Shao-Nong; Pauli, Guido F

    2017-10-20

    The 9th International Countercurrent Chromatography Conference (CCC 2016) was held at Dominican University near Chicago, IL (USA), from August 1st-3rd, 2016. The biennial CCC 20XX conferences provide an opportunity for countercurrent chromatography and centrifugal partition chromatography (CCC/CPC) manufactures, marketers, theorists, and research scientists to gather together socially, learn from each other, and advance countercurrent separation technology. A synopsis of the conference proceedings as well as a series of short reviews of the special edition articles is included in this document. Many productive discussions and collegial conversation at CCC 2016 attested to the liveliness, connectivity, and productivity of the global countercurrent research community and bodes well for the success of the 10th conference at the University of Braunschweig, Germany on August 1-3, 2018. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Formerly utilized MED/AEC sites remedial action program: radiological survey of the Museum of Science and Industry, 57th Street and Lake Shore Drive, Chicago, Illinois. Final report

    International Nuclear Information System (INIS)

    1979-02-01

    From August 15, 1946 until July 15, 1953, ANL occupied part of the Museum of Science and Industry in Chicago; some handling of radioactive materials took place. In a radiation survey taken of the areas in 1977, instrument and smear surveys were made, and air and soil samples were counted. Results indicate there is no identifiable residual radioactivity remaining from MED/AEC operations during the period 1946 through 1953

  8. Internalization of interleukin 1 (IL 1) correlates with IL 1-induced IL 2 receptor expression and IL 2 secretion of EL4 thymoma cells

    OpenAIRE

    Von Hoegen, I.; Falk, Werner; Kojouharoff, G.; Krammer, P. H.

    1989-01-01

    The cytokine interleukin 1 (IL 1) plays an important role in the induction of IL 2 secretion and high-affinity IL 2 receptor (IL 2R) expression by T cells. The events that follow binding of IL 1 to IL 1R, however, are still unknown. In this study we describe two variants of the murine thymoma EL4 (5D3 and D6/76) that express comparable numbers of cell surface IL 1 receptors and bind IL 1 with the same affinity, but show distinct IL 1-dependent IL 2 secretion and IL 2R expression. In the prese...

  9. Teatrireisikiri. USA. Chicago. Aprill 2009 / Rednar Annus

    Index Scriptorium Estoniae

    Annus, Rednar, 1970-

    2009-01-01

    Chicago Improv Festivalist. Kahest nähtud lavastustest: William Gibsoni "The Miracle worker" ja Alan Bennetti "Ajaloopoisid". Kahest nähtud muusikalist: Michael Bennetti "A Corus Line" ja Disney ning Cameron Macintoshi "Mary Poppins"

  10. Generative Street Addresses from Satellite Imagery

    Directory of Open Access Journals (Sweden)

    İlke Demir

    2018-03-01

    Full Text Available We describe our automatic generative algorithm to create street addresses from satellite images by learning and labeling roads, regions, and address cells. Currently, 75% of the world’s roads lack adequate street addressing systems. Recent geocoding initiatives tend to convert pure latitude and longitude information into a memorable form for unknown areas. However, settlements are identified by streets, and such addressing schemes are not coherent with the road topology. Instead, we propose a generative address design that maps the globe in accordance with streets. Our algorithm starts with extracting roads from satellite imagery by utilizing deep learning. Then, it uniquely labels the regions, roads, and structures using some graph- and proximity-based algorithms. We also extend our addressing scheme to (i cover inaccessible areas following similar design principles; (ii be inclusive and flexible for changes on the ground; and (iii lead as a pioneer for a unified street-based global geodatabase. We present our results on an example of a developed city and multiple undeveloped cities. We also compare productivity on the basis of current ad hoc and new complete addresses. We conclude by contrasting our generative addresses to current industrial and open solutions.

  11. Public Reactions to New Street Tree Planting

    Directory of Open Access Journals (Sweden)

    Ruth A. Rae

    2010-01-01

    Full Text Available MillionTreesNYC, which has the goal of planting one million trees in New York City by 2017, is intended to make New York City a greener, more sustainable city and is part of the Mayor’s comprehensive long term strategic plan, PlaNYC. Through planting a tree at every suitable sidewalk location in the city, the City of New York is transforming blocks and communities, and providing a variety of environmental, social and aesthetic benefits. This article examines the large scale municipal planting of new street trees and the reaction by some of the pubic to this planting.Trees offer benefits to the city overall, but the public may not understand these benefits or the street tree planting process. Between 2007 and 2009, the Department of Parks & Recreation planted 53,235 new street trees, and received 4,108 items of correspondence from the public. The majority of this correspondence consisted of public comments about the City’s new street tree planting policies and processes including placement objections, maintenance concerns, reports of resultant damage from tree planting operations, requests for new street trees and reports of tree conditions.This study describes the operational policies that guide New York City's municipal street tree planting, and results of content and spatial analysis of the correspondence. Qualitative analysis of the correspondence revealed the public perceptions and concerns related to the MillionTreesNYC program. Spatial analysis explored the relationship between the planting locations of new street trees and the locations of the citizen correspondence.Public reactions to this large scale municipal planting are related to the dual public and private nature of the sidewalk, issues of territoriality, responsibility, aesthetics and place attachment. Correspondence volume was associated with the scale of the new street tree block planting program, and the effectiveness of NYC’s 311 Customer Service Center. The discussion

  12. Passive control potentials of trees and on-street parked cars in reduction of air pollution exposure in urban street canyons

    International Nuclear Information System (INIS)

    Abhijith, K.V.; Gokhale, Sharad

    2015-01-01

    This study investigates the passive-control-potentials of trees and on-street parked cars on pedestrian exposure to air pollutants in a street canyon using three-dimensional CFD. Since, according to some studies trees deteriorate air quality and cars parked roadside improve it, the combine as well as separate effects of trees and on-street parked cars have been examined. For this, different tree canopy layouts and parking configurations have been developed and pedestrian exposure for each has been analysed. The results showed, for example, tree crown with high porosity and low-stand density in combination with parallel or perpendicular car parking reduced the pedestrian exposure considerably. - Highlights: • Trees and on-street parked cars can manipulate pollutant levels in street canyons. • Low stand density trees with 0° or 90° car parking reduce pedestrian exposure. • Trees with medium crown, high porosity, low stand density reduce pollutant levels. - This study investigated the combination of trees and on-street parked cars to manipulate pollutant levels in urban street canyons to reduce pedestrian exposure

  13. 76 FR 38891 - Companies Holding Certificates of Authority as Acceptable Sureties on Federal Bonds and as...

    Science.gov (United States)

    2011-07-01

    ...) BUSINESS ADDRESS: 333 S. WABASH AVE, CHICAGO, IL 60604. PHONE: (312) 822-5000. UNDERWRITING LIMITATION b... IN: Indiana. American Fire and Casualty Company (NAIC 24066) BUSINESS ADDRESS: 9450 Seward Road... ADDRESS: 333 S. WABASH AVE, CHICAGO, IL 60604. PHONE: (312) 822-5000. UNDERWRITING LIMITATION b/: $795,783...

  14. 78 FR 39439 - Companies Holding Certificates of Authority as Acceptable Sureties on Federal Bonds and as...

    Science.gov (United States)

    2013-07-01

    ... Company of Reading, Pennsylvania (NAIC 20427) BUSINESS ADDRESS: 333 S. WABASH AVE, CHICAGO, IL 60604..., UT, VA, WA, WV, WI, WY. INCORPORATED IN: California. American Fire and Casualty Company (NAIC 24066... Carolina. Continental Casualty Company (NAIC 20443) BUSINESS ADDRESS: 333 S. WABASH AVE, CHICAGO, IL 60604...

  15. Tappev kuulsus viib Chicago lavale / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2003-01-01

    Muusikafilm "Chicago", mille aluseks John Kanderi - Fred Ebb'i muusikal : režissöör Rob Marshall : Ameerika Ühendriigid 2002. 1975.a. selle muusikali Broadwayl lavale toonud Bob Fosse mõjust filmi stiilile

  16. The Chicago guide to communicating science

    CERN Document Server

    Montgomery, Scott L

    2017-01-01

    For more than a decade, The Chicago Guide to Communicating Science has been the go-to reference for anyone who needs to write or speak about their research. Whether a student writing a thesis, a faculty member composing a grant proposal, or a public information officer crafting a press release, Scott Montgomery’s advice is perfectly adaptable to any scientific writer’s needs. This new edition has been thoroughly revised to address crucial issues in the changing landscape of scientific communication, with an increased focus on those writers working in corporate settings, government, and nonprofit organizations as well as academia. Half a dozen new chapters tackle the evolving needs and paths of scientific writers. These sections address plagiarism and fraud, writing graduate theses, translating scientific material, communicating science to the public, and the increasing globalization of research. The Chicago Guide to Communicating Science recognizes that writers come to the table with different needs and...

  17. 75 FR 70691 - World Color Mt. Morris, IL LLC, Premedia Chicago Division, Currently Known as Quad/Graphics, Inc...

    Science.gov (United States)

    2010-11-18

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,142] World Color Mt. Morris... to Apply for Worker Adjustment Assistance on May 24, 2010, applicable to workers of World Color Mt... that on July 2, 2010, World Color Mt. Morris, IL LLC was purchased by Quad/Graphics, Inc. and is...

  18. 76 FR 7849 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2011-02-11

    ... Federal Reserve Bank indicated. The notices also will be available for inspection at the offices of the... South LaSalle Street, Chicago, Illinois 60690-1414: 1. Charles M. Shea, Wilmette, Illinois; as an..., Chicago, Illinois, Charles M. Shea, Wilmette, Illinois, as Trustee, and Molly Boed, Wassenaar, Netherlands...

  19. [Street social education: historical, political and pedagogical bases].

    Science.gov (United States)

    de Oliveira, Walter Ferreira

    2007-01-01

    This work is about street social education as a pedagogical system that started in Latin America in the late 1970s, as the street population formed mostly by children and adolescents called for attention. The first street social educators were 'pastoral' agents working at the praça da Sé a place with large numbers of street children in São Paulo. Based on the Liberation Theology and on the pedagogies developed by Paulo Freire, Celestine Freinet, Anton Makarenko, and Emília Ferreiro, the street educators developed a conceptual field and participated in the promulgation of the 1988 Federal Constitution, particularly by writing and introducing the 'Estatuto da Criança e do Adolescente' (the 'Child and Adolescent Statute'). Street social education is currently latent and suffering the consequences of program discontinuity caused by successive changes of government. It is, therefore important to know the conceptual proposals.

  20. Alcohol in urban streetscapes: a comparison of the use of Google Street View and on-street observation.

    Science.gov (United States)

    Clews, Chris; Brajkovich-Payne, Roza; Dwight, Emily; Ahmad Fauzul, Ayob; Burton, Madeleine; Carleton, Olivia; Cook, Julie; Deroles, Charlotte; Faulkner, Ruby; Furniss, Mary; Herewini, Anahera; Huband, Daymen; Jones, Nerissa; Kim, Cho Wool; Li, Alice; Lu, Jacky; Stanley, James; Wilson, Nick; Thomson, George

    2016-05-26

    Alcohol-related harm is a major global health issue, and controls on alcohol marketing are one intervention utilized by governments. This study investigated the use of Google Street View (GSV) as a novel research method for collecting alcohol-related data in the urban environment. The efficacy of GSV and on-street observation by observer teams was compared by surveying 400 m stretches of 12 streets in Wellington, the capital city of New Zealand. Data on alcohol sale, alcohol-related advertising, health promotion materials, regulatory information and visible alcohol consumption were collected. A total of 403 retailers with evidence of alcohol sales and 1161 items of alcohol-related communication were identified in on-street observation. Of the latter, 1028 items (89 %) were for alcohol marketing and 133 (11 %) were for alcohol-related health promotion and alcohol regulation. GSV was found to be a less sensitive tool than on-street observation with only 50 % of the alcohol venues identified and 52 % of the venue-associated brand marketing identified. A high degree of inter-observer reliability was generally found between pairs of observers e.g., for the detection of alcohol retail venues the intra-class correlation coefficient (ICC) was 0.93 (95 % CI: 0.78 to 0.98) for on-street observation and 0.85 (95 % CI: 0.49 to 0.96) for using GSV. GSV does not seem suitable for the comprehensive study of the influences on alcohol consumption in the urban streetscape. However, it may still have value for large, static objects in the environment and be more time efficient than traditional on-street observation measures, especially when used to collect data across a wide geographical area. Furthermore, GSV might become a more useful research tool in settings with better image quality (such as more 'footpath views') and with more regularly updated GSV imagery.

  1. Chicago section activities to enhance public acceptance of nuclear power

    International Nuclear Information System (INIS)

    Snyder, T.L.; Keffer, J.W.

    1992-01-01

    The Chicago section of the American Nuclear Society (ANS) is an active organization with ∼450 members. The local section territory encompasses northern Illinois and includes in its territory all six of Commonwealth Edison Company's (CECo's) nuclear generating stations as well as Argonne National Laboratory (ANL). Included in the territory are several large engineering firms - ABB Impell, Bechtel, Fluor Daniel, and Sargent ampersand Lundy. The national headquarters of the ANS is also located within the local section boundaries. All these organizations are represented in the local section membership and provide access to abundant technical resources that can be used to enhance public acceptance of nuclear power. An important attribute of any local section that enables it to perform interesting programs and be active in the community is its financial resources. The Chicago section has a strong financial base because of its ability to raise funds by participating in and sponsoring ANS topical and other meetings. For instance, in 1991, they sponsored and were actively involved in the Emergency Preparedness Topical Meeting held in Chicago. In 1992, they were actively involved in sponsoring the organizational activities of the ANS/ENS International Meeting, which will celebrate the 50th year of nuclear fission. The financial and technical resources of the Chicago section continue to contribute to a successful program of public education and public acceptance activities regarding the nuclear industry

  2. HYDROGEOLOGIC CASE STUDIES (CHICAGO, IL)

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  3. Detecting Themed Streets Using a Location Based Service Application

    Directory of Open Access Journals (Sweden)

    Byeongsuk Ji

    2016-07-01

    Full Text Available Various themed streets have recently been developed by local governments in order to stimulate local economies and to establish the identity of the corresponding places. However, the motivations behind the development of some of these themed street projects has been based on profit, without full considerations of people’s perceptions of their local areas, resulting in marginal effects on the local economies concerned. In response to this issue, this study proposed a themed street clustering method to detect the themed streets of a specific region, focusing on the commercial themed street, which is more prevalent than other types of themed streets using location based service data. This study especially uses “the street segment” as a basic unit for analysis. The Sillim and Gangnam areas of Seoul, South Korea were chosen for the evaluation of the adequacy of the proposed method. By comparing trade areas that were sourced from a market analysis report by a reliable agent with the themed streets detected in this study, the experiment results showed high proficiency of the proposed method.

  4. Clinical significance of determination of changes of serum IL-6, IL-8, IL-10 and IL-18 levels after treatment in patients with chronic renal diseases

    International Nuclear Information System (INIS)

    Liu Congjiang; Li Fen; Zhang Lei; Liu Jianhua

    2008-01-01

    Objective: To explore the changes of serum IL-6, IL-8, IL-10 and IL-18 levels after treatment in patients with chronic renal diseases. Methods: Serum IL-6, IL-8, IL-10 levels were determined with RIA and IL-18 levels with ELISA in 32 patients with chronic renal diseases both before and after treatment as well as in 35 controls. Results: Before treatment the serum IL -6, IL-8, IL-10 and IL-18 levels were significantly higher in the patients than those in controls (P<0.01). After 6 months of treatment, the levels though dropped markedly remained significantly higher (P<0.05). Conclusion: Levels of serum IL-6, IL- 8, IL-10 and IL-18 increased significantly in patients with chronic renal diseases, especially in those advanced cases. (authors)

  5. Modelling Pollutant Dispersion in a Street Network

    Science.gov (United States)

    Salem, N. Ben; Garbero, V.; Salizzoni, P.; Lamaison, G.; Soulhac, L.

    2015-04-01

    This study constitutes a further step in the analysis of the performances of a street network model to simulate atmospheric pollutant dispersion in urban areas. The model, named SIRANE, is based on the decomposition of the urban atmosphere into two sub-domains: the urban boundary layer, whose dynamics is assumed to be well established, and the urban canopy, represented as a series of interconnected boxes. Parametric laws govern the mass exchanges between the boxes under the assumption that the pollutant dispersion within the canopy can be fully simulated by modelling three main bulk transfer phenomena: channelling along street axes, transfers at street intersections, and vertical exchange between street canyons and the overlying atmosphere. Here, we aim to evaluate the reliability of the parametrizations adopted to simulate these phenomena, by focusing on their possible dependence on the external wind direction. To this end, we test the model against concentration measurements within an idealized urban district whose geometrical layout closely matches the street network represented in SIRANE. The analysis is performed for an urban array with a fixed geometry and a varying wind incidence angle. The results show that the model provides generally good results with the reference parametrizations adopted in SIRANE and that its performances are quite robust for a wide range of the model parameters. This proves the reliability of the street network approach in simulating pollutant dispersion in densely built city districts. The results also show that the model performances may be improved by considering a dependence of the wind fluctuations at street intersections and of the vertical exchange velocity on the direction of the incident wind. This opens the way for further investigations to clarify the dependence of these parameters on wind direction and street aspect ratios.

  6. Psychosocial profile of institutionalised street children in Alexandria ...

    African Journals Online (AJOL)

    Objective: The phenomenon of street children in Egypt constitutes a public health concern. This study aimed to investigate the characteristics of institutionalised street children in Alexandria, to compare the prevalence of substance abuse and conduct disorder between street children and school children, and to identify ...

  7. Street Food Consumption and its associated socio-demographic ...

    African Journals Online (AJOL)

    Street Food Consumption and its associated socio-demographic factors in Oyo town, Nigeria. ... Abstract. Background: Contemporary life-styles have made street foods to be an important meal option in Nigeria. They contribute ... Nutrition education is suggested for people to make a better choice of nourishing street foods.

  8. 75 FR 38191 - Companies Holding Certificates of Authority as Acceptable Sureties on Federal Bonds and as...

    Science.gov (United States)

    2010-07-01

    ..., Pennsylvania (NAIC 20427) BUSINESS ADDRESS: 333 S. WABASH AVE, CHICAGO, IL 60604. PHONE: (312) 822-5000.... INCORPORATED IN: Indiana. American Fire and Casualty Company (NAIC 24066) BUSINESS ADDRESS: 9450 Seward Road... Casualty Company (NAIC 20443) BUSINESS ADDRESS: 333 S. WABASH AVE, CHICAGO, IL 60604. PHONE: (312) 822-5000...

  9. 75 FR 70921 - Simon Property Group, Inc.; Analysis of Proposed Agreement Containing Consent Orders To Aid...

    Science.gov (United States)

    2010-11-19

    ... tenant in either of the following geographic areas: the Chicago, IL, metropolitan area or Orlando, FL... Orlando, Prime Outlets Orlando Marketplace, and Orlando Premium Outlets may unilaterally opt to extend any... competition in the provision of retail space at outlet centers in the Southwest Ohio; Chicago, IL; and Orlando...

  10. Back to Bed: From Hospital to Home Obstetrics in the City of Chicago.

    Science.gov (United States)

    Kline, Wendy

    2018-01-01

    This article analyzes the role of doctors and activists in Chicago who successfully redefined the practice and politics of childbirth both locally and ultimately nationwide. It begins with the story of Joseph DeLee's Chicago Maternity Center, responsible for supervising over 100,000 home births between 1932 and 1972. Most of the mothers cared for by the Center were nonwhite, poor, and had little or no access to prenatal care, yet their babies had a far higher survival rate than the nationwide average. Thousands of medical students from all over the Midwest experienced their first deliveries not in hospitals, but in these homes. The article then addresses a very different demographic: a rising number of middle-class white families in the suburbs of Chicago who, beginning in the 1950s, opted for out-of-hospital births. Many of them learned about home birth through their involvement in La Leche League, the breastfeeding organization formed in a Chicago suburb in 1956. Seemingly separated by class, race, and locale, the link between these two groups of home birthers was the philosophy and training in place at the Chicago Maternity Center. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  11. On the escape of pollutants from urban street canyons

    Energy Technology Data Exchange (ETDEWEB)

    Baik, J.J.; Kim, J.J. [Kwangju Inst. of Science and Technology (Korea). Dept. of Environmental Science and Engineering

    2002-07-01

    Pollutant transport from urban street canyons is numerically investigated using a two-dimensional flow and dispersion model. The ambient wind blows perpendicular to the street and passive pollutants are released at the street level. Results from the control experiment with a street aspect ratio of 1 show that at the roof level of the street canyon, the vertical turbulent flux of pollutants is upward everywhere and the vertical flux of pollutants by mean flow is upward or downward. The horizontally integrated vertical flux of pollutants by mean flow at the roof level of the street canyon is downward and its magnitude is much smaller than that by turbulent process. These results indicate that pollutants escape from the street canyon mainly by turbulent process and that the net effect of mean flow is to make some escaped pollutants reenter the street canyon. Further experiments with different inflow turbulence intensities, inflow wind speeds, and street aspect ratio confirm the findings from the control experiment. In the case of two isolated buildings, the horizontally integrated vertical flux of pollutants by mean flow is upward due to flow separation but the other main results are the same as those from the control experiment. (author)

  12. Chicago's water market: Dynamics of demand, prices and scarcity rents

    Science.gov (United States)

    Ipe, V.C.; Bhagwat, S.B.

    2002-01-01

    Chicago and its suburbs are experiencing an increasing demand for water from a growing population and economy and may experience water scarcity in the near future. The Chicago metropolitan area has nearly depleted its groundwater resources to a point where interstate conflicts with Wisconsin could accompany an increased reliance on those sources. Further, the withdrawals from Lake Michigan is limited by the Supreme Court decree. The growing demand and indications of possible scarcity suggest a need to reexamine the pricing policies and the dynamics of demand. The study analyses the demand for water and develops estimates of scarcity rents for water in Chicago. The price and income elasticities computed at the means are -0.002 and 0.0002 respectively. The estimated scarcity rents ranges from $0.98 to $1.17 per thousand gallons. The results indicate that the current prices do not fully account for the scarcity rents and suggest a current rate with in the range $1.53 to $1.72 per thousand gallons.

  13. IFN-γ, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13

    Directory of Open Access Journals (Sweden)

    Michoud Marie-Claire

    2008-12-01

    Full Text Available Abstract Background IL-13 is a critical mediator of allergic asthma and associated airway hyperresponsiveness. IL-13 acts through a receptor complex comprised of IL-13Rα1 and IL-4Rα subunits with subsequent activation of signal transducer and activator of transcription 6 (STAT6. The IL-13Rα2 receptor may act as a decoy receptor. In human airway smooth muscle (HASM cells, IL-13 enhances cellular proliferation, calcium responses to agonists and induces eotaxin production. We investigated the effects of pre-treatment with IL-4, IL-13 and IFN-γ on the responses of HASM cells to IL-13. Methods Cultured HASM were examined for expression of IL-13 receptor subunits using polymerase chain reaction, immunofluorescence microscopy and flow cytometry. Effects of cytokine pre-treatment on IL-13-induced cell responses were assessed by looking at STAT6 phosphorylation using Western blot, eotaxin secretion and calcium responses to histamine. Results IL-13Rα1, IL-4Rα and IL-13Rα2 subunits were expressed on HASM cells. IL-13 induced phosphorylation of STAT6 which reached a maximum by 30 minutes. Pre-treatment with IL-4, IL-13 and, to a lesser degree, IFN-γ reduced peak STAT6 phosphorylation in response to IL-13. IL-13, but not IFN-γ, pre-treatment abrogated IL-13-induced eotaxin secretion. Pre-treatment with IL-4 or IL-13 abrogated IL-13-induced augmentation of the calcium transient evoked by histamine. Cytokine pre-treatment did not affect expression of IL-13Rα1 and IL-4Rα but increased expression of IL-13Rα2. An anti-IL-13Rα2 neutralizing antibody did not prevent the cytokine pre-treatment effects on STAT6 phosphorylation. Cytokine pre-treatment increased SOCS-1, but not SOCS-3, mRNA expression which was not associated with significant increases in protein expression. Conclusion Pre-treatment with IL-4 and IL-13, but not IFN-γ, induced desensitization of the HASM cells to IL-13 as measured by eotaxin secretion and calcium transients to histamine

  14. 78 FR 27246 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-09

    ... personal privacy. Name of Committee: Bioengineering Sciences & Technologies Integrated Review Group....m. Agenda: To review and evaluate grant applications. Place: St. Gregory Hotel, 2033 M Street NW.... Agenda: To review and evaluate grant applications. Place: Avenue Hotel Chicago, 160 E. Huron Street...

  15. Social and economic characteristics of street youth by gender and level of street involvement in Eldoret, Kenya.

    Directory of Open Access Journals (Sweden)

    Rebecca Sorber

    Full Text Available Street-connected youth are a neglected and vulnerable population, particularly in resource-constrained settings. The development of interventions and supports for this population requires insight into how they live. This study describes the social and economic characteristics of a convenience sample of street youth (SY in Eldoret, Kenya.Participants were eligible if they were aged 12-21, living in Eldoret, spending days only (part-time, or nights and days on the street (full-time and able and willing to consent or assent. Data were collected using a standardized interview conducted in English or Kiswahili. Binary dependent variables were having been arrested and/or jailed, and first priority for spending money (food vs. other. Nominal categorical dependent variables included major source of support, and major reason for being street-involved. Multivariable analysis used logistic regression models to examine the association of gender and level of street-involvement with social and economic factors of interest adjusting for age and length of time on the street. Data were analyzed using SAS 9.3.Of the 200 SY enrolled, 41% were female, mean age of 16.3 years; 71% were on the street full-time, and 29% part-time. Compared with part-time SY, full-time SY were more likely to have been arrested (Adjusted Odds Ratio [AOR]: 2.33, 95% Confidence Interval [95%CI]:1.01-5.35, name food as their first spending priority (AOR: 2.57, 95%CI:1.03-6.45, have left home due to violence (AOR: 5.54, 95%CI: 1.67-18.34, and more likely to report friends on the street as a major source of support (AOR: 3.59, 95% CI: 1.01-12.82. Compared with females, males were more likely to have ever been arrested (AOR: 2.66, 95%CI:1.14-6.18, and to have ever been jailed (AOR: 3.22, 95%CI:1.47-7.02.These results suggest a high degree of heterogeneity and vulnerability among SY in this setting. There is an urgent need for interventions taking into consideration these characteristics.

  16. OpenStreetMap over WMS

    Directory of Open Access Journals (Sweden)

    Přemysl Vohnout

    2010-02-01

    Full Text Available This paper discuss the issues which we faced, while preparing WMS server with OpenStreetMap data of whole Europe. This article is divided into three sections. First is about mandatory applications which are required for working WMS service with OpenStreetMap data. Second is focused on tuning up PostgreSQL. Third is focused on rendering time improvement of layers.

  17. IL-33 Enhanced the Proliferation and Constitutive Production of IL-13 and IL-5 by Fibrocytes

    Directory of Open Access Journals (Sweden)

    Hisako Hayashi

    2014-01-01

    Full Text Available Interleukin-33 appears to play important roles in the induction of allergic airway inflammation. However, whether IL-33 is involved in airway remodeling remains unclear. Because fibrocytes contribute to tissue remodeling in the setting of chronic inflammation, we examined the effects of IL-33 on fibrocyte functions. Fibrocytes were generated in vitro from peripheral blood mononuclear cells by culturing in the presence of platelet derived growth factors and the cells were stimulated with IL-33. IL-33 enhanced cell proliferation, α-SMA expression, and pro-MMP-9 activity by the fibrocytes without increasing endogenous transforming growth factor-β1 production. Fibrocytes constitutively expressed IL-13 and IL-5, and their production was augmented by stimulation with IL-33. Dexamethasone inhibited the functions of fibrocytes, but IL-33 made fibrocytes slightly refractory to the inhibitory effect of dexamethasone in terms of IL-13 production. Montelukast suppressed IL-13 production by nonstimulated fibrocytes but not those stimulated by IL-33. These findings suggest that IL-33 is involved in the airway remodeling process through its modulation of fibrocyte function independent of antigen stimulation. IL-33 might partially reduce the therapeutic effects of glucocorticoid and cysteinyl leukotriene receptor antagonist on fibrocyte-mediated Th2 responses.

  18. POLE-LIKE STREET FURNITURE DECOMPOSTION IN MOBILE LASER SCANNING DATA

    Directory of Open Access Journals (Sweden)

    F. Li

    2016-06-01

    Full Text Available Automatic semantic interpretation of street furniture has become a popular topic in recent years. Current studies detect street furniture as connected components of points above the street level. Street furniture classification based on properties of such components suffers from large intra class variability of shapes and cannot deal with mixed classes like traffic signs attached to light poles. In this paper, we focus on the decomposition of point clouds of pole-like street furniture. A novel street furniture decomposition method is proposed, which consists of three steps: (i acquirement of prior-knowledge, (ii pole extraction, (iii components separation. For the pole extraction, a novel global pole extraction approach is proposed to handle 3 different cases of street furniture. In the evaluation of results, which involves the decomposition of 27 different instances of street furniture, we demonstrate that our method decomposes mixed classes street furniture into poles and different components with respect to different functionalities.

  19. Pole-Like Street Furniture Decompostion in Mobile Laser Scanning Data

    Science.gov (United States)

    Li, F.; Oude Elberink, S.; Vosselman, G.

    2016-06-01

    Automatic semantic interpretation of street furniture has become a popular topic in recent years. Current studies detect street furniture as connected components of points above the street level. Street furniture classification based on properties of such components suffers from large intra class variability of shapes and cannot deal with mixed classes like traffic signs attached to light poles. In this paper, we focus on the decomposition of point clouds of pole-like street furniture. A novel street furniture decomposition method is proposed, which consists of three steps: (i) acquirement of prior-knowledge, (ii) pole extraction, (iii) components separation. For the pole extraction, a novel global pole extraction approach is proposed to handle 3 different cases of street furniture. In the evaluation of results, which involves the decomposition of 27 different instances of street furniture, we demonstrate that our method decomposes mixed classes street furniture into poles and different components with respect to different functionalities.

  20. 75 FR 69444 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2010-11-12

    ... November 26, 2010. A. Federal Reserve Bank of Chicago (Colette A. Fried, Assistant Vice President) 230 South LaSalle Street, Chicago, Illinois 60690-1414: 1. Robert John Dentel, Victor, Iowa, and Mary P. Howell, Ames, Iowa, individually; and the Robert John Dentel Family (Robert J. Dentel, Patricia A. Dentel...

  1. A review of variables of urban street connectivity for spatial connection

    International Nuclear Information System (INIS)

    Mohamad, W S N W; Said, I

    2014-01-01

    Several studies on street connectivity in cities and towns have been modeled on topology, morphology, technology and psychology of people living in the urban environment. Street connectivity means the connection of streets that offers people alternative routes. However, there emerge difficulties to determine the suitable variables and analysis to be chosen in defining the accurate result for studies street connectivity. The aim of this paper is to identify variables of street connectivity by applying GIS and Space Syntax. This paper reviews the variables of street connectivity from 15 past articles done in 1990s to early 2000s from journals of nine disciplines on Environment and Behavior, Planning and Design, Computers, Environment and Urban Systems, Applied Earth Observation and Geo-information, Environment and Planning, Physica A: Statistical Mechanics and its Applications, Environmental Psychology, Social Science and Medicine and Building and Environment. From the review, there are four variables found for street connectivity: link (streets-streets, street-nodes or node-streets, nodes-nodes), accessibility, least-angle, and centrality. Space syntax and GIS are suitable tools to analyze the four variables relating to systematic street systems for pedestrians. This review implies that planners of the street systems, in the aspect of street connectivity in cities and towns, should consider these four variables

  2. A review of variables of urban street connectivity for spatial connection

    Science.gov (United States)

    Mohamad, W. S. N. W.; Said, I.

    2014-02-01

    Several studies on street connectivity in cities and towns have been modeled on topology, morphology, technology and psychology of people living in the urban environment. Street connectivity means the connection of streets that offers people alternative routes. However, there emerge difficulties to determine the suitable variables and analysis to be chosen in defining the accurate result for studies street connectivity. The aim of this paper is to identify variables of street connectivity by applying GIS and Space Syntax. This paper reviews the variables of street connectivity from 15 past articles done in 1990s to early 2000s from journals of nine disciplines on Environment and Behavior, Planning and Design, Computers, Environment and Urban Systems, Applied Earth Observation and Geo-information, Environment and Planning, Physica A: Statistical Mechanics and its Applications, Environmental Psychology, Social Science and Medicine and Building and Environment. From the review, there are four variables found for street connectivity: link (streets-streets, street-nodes or node-streets, nodes-nodes), accessibility, least-angle, and centrality. Space syntax and GIS are suitable tools to analyze the four variables relating to systematic street systems for pedestrians. This review implies that planners of the street systems, in the aspect of street connectivity in cities and towns, should consider these four variables.

  3. IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis.

    Directory of Open Access Journals (Sweden)

    Paméla Gasse

    Full Text Available BACKGROUND: Idiopathic pulmonary fibrosis is a devastating as yet untreatable disease. We demonstrated recently the predominant role of the NLRP3 inflammasome activation and IL-1β expression in the establishment of pulmonary inflammation and fibrosis in mice. METHODS: The contribution of IL-23 or IL-17 in pulmonary inflammation and fibrosis was assessed using the bleomycin model in deficient mice. RESULTS: We show that bleomycin or IL-1β-induced lung injury leads to increased expression of early IL-23p19, and IL-17A or IL-17F expression. Early IL-23p19 and IL-17A, but not IL-17F, and IL-17RA signaling are required for inflammatory response to BLM as shown with gene deficient mice or mice treated with neutralizing antibodies. Using FACS analysis, we show a very early IL-17A and IL-17F expression by RORγt(+ γδ T cells and to a lesser extent by CD4αβ(+ T cells, but not by iNKT cells, 24 hrs after BLM administration. Moreover, IL-23p19 and IL-17A expressions or IL-17RA signaling are necessary to pulmonary TGF-β1 production, collagen deposition and evolution to fibrosis. CONCLUSIONS: Our findings demonstrate the existence of an early IL-1β-IL-23-IL-17A axis leading to pulmonary inflammation and fibrosis and identify innate IL-23 and IL-17A as interesting drug targets for IL-1β driven lung pathology.

  4. Sensation Seeking in Street Violence

    DEFF Research Database (Denmark)

    Heinskou, Marie Bruvik; Liebst, Lasse Suonperä

    Sensation seeking leads to violence—runs an influential hypothesis in the social scientific study of violent behavior. Although studies confirm that violence is sometimes structured by sensation-seeking motives, the literature seldom comments on the limits to this explanation of violence....... The present study examines the scale of violence motivated by sensation seeking and the degree to which there are several distinct forms of sensation seeking motives operative in violence, rather than a sensation-seeking motive in the singular. The study draws on a sample of situations from Copenhagen...... involving street violence, which are coded quantitatively and qualitatively. Our analysis shows that sensation seeking only seldom seems to play a role in the structuring of street violence. Moreover, the data indicate that sensation seeking finds expression in street violence situations in two different...

  5. Emergency epinephrine use for food allergy reactions in Chicago Public Schools.

    Science.gov (United States)

    DeSantiago-Cardenas, Lilliana; Rivkina, Victoria; Whyte, Stephanie A; Harvey-Gintoft, Blair C; Bunning, Bryan J; Gupta, Ruchi S

    2015-02-01

    Given the increase in childhood food allergy, national and local policies have been developed to encourage schools to stock undesignated epinephrine auto-injectors in case of an anaphylactic emergency. To describe the use of epinephrine auto-injectors in Chicago Public Schools during the 2012-2013 school year, specifically for food-induced allergic reactions. District-issued epinephrine auto-injectors were distributed to all public and charter schools in Chicago prior to the start of the 2012-2013 school year. Data on their use were collected, and frequencies were computed in the autumn of 2013. Thirty-eight district-issued epinephrine auto-injectors were administered during the inaugural year of the Chicago Public Schools initiative. Epinephrine auto-injectors were administered to students (92.1%) and school staff (7.9%). Most district-issued epinephrine auto-injectors were administered in elementary schools (63.2%) and on Chicago's North-Northwest Side (36.8%). More than half (55.0%) of all district-issued epinephrine auto-injectors were administered for first-time anaphylactic events. Food-induced reactions accounted for more than half (55.3%) of all reactions requiring epinephrine auto-injector use, whereas the trigger of more than one third (34.2%) of all reactions requiring the use of an epinephrine auto-injector remained unknown. Chicago Public Schools is the first large, urban school district in the U.S. to develop and implement the District-Issued Emergency Epinephrine Initiative, which helped 38 students and staff avoid potential morbidity and mortality. The impact of this initiative during its first year underscores the need for stocking undesignated epinephrine in schools across the country. Copyright © 2015 American Journal of Preventive Medicine. All rights reserved.

  6. Characteristics of flow and reactive pollutant dispersion in urban street canyons

    Science.gov (United States)

    Park, Soo-Jin; Kim, Jae-Jin; Kim, Minjoong J.; Park, Rokjin J.; Cheong, Hyeong-Bin

    2015-05-01

    In this study, the effects of aspect ratio defined as the ratio of building height to street width on the dispersion of reactive pollutants in street canyons were investigated using a coupled CFD-chemistry model. Flow characteristics for different aspect ratios were analyzed first. For each aspect ratio, six emission scenarios with different VOC-NOX ratios were considered. One vortex was generated when the aspect ratio was less than 1.6 (shallow street canyon). When the aspect ratio was greater than 1.6 (deep street canyon), two vortices were formed in the street canyons. Comparing to previous studies on two-dimensional street canyons, the vortex center is slanted toward the upwind building and reverse and downward flows are dominant in street canyons. Near the street bottom, there is a marked difference in flow pattern between in shallow and deep street canyons. Near the street bottom, reverse and downward flows are dominant in shallow street canyon and flow convergence exists near the center of the deep street canyons, which induces a large difference in the NOX and O3 dispersion patterns in the street canyons. NOX concentrations are high near the street bottom and decreases with height. The O3 concentrations are low at high NO concentrations near the street bottom because of NO titration. At a low VOC-NOX ratio, the NO concentrations are sufficiently high to destroy large amount of O3 by titration, resulting in an O3 concentration in the street canyon much lower than the background concentration. At high VOC-NOX ratios, a small amount of O3 is destroyed by NO titration in the lower layer of the street canyons. However, in the upper layer, O3 is formed through the photolysis of NO2 by VOC degradation reactions. As the aspect ratio increases, NOX (O3) concentrations averaged over the street canyons decrease (increase) in the shallow street canyons. This is because outward flow becomes strong and NOX flux toward the outsides of the street canyons increases

  7. Quantitative Contribution of IL2Rγ to the Dynamic Formation of IL2-IL2R Complexes.

    Directory of Open Access Journals (Sweden)

    Luis F Ponce

    Full Text Available Interleukin-2 (IL2 is a growth factor for several immune cells and its function depends on its binding to IL2Rs in the cell membrane. The most accepted model for the assembling of IL2-IL2R complexes in the cell membrane is the Affinity Conversion Model (ACM. This model postulates that IL2R receptor association is sequential and dependent on ligand binding. Most likely free IL2 binds first to IL2Rα, and then this complex binds to IL2Rβ, and finally to IL2Rγ (γc. However, in previous mathematical models representing this process, the binding of γc has not been taken into account. In this work, the quantitative contribution of the number of IL2Rγ chain to the IL2-IL2R apparent binding affinity and signaling is studied. A mathematical model of the affinity conversion process including the γ chain in the dynamic, has been formulated. The model was calibrated by fitting it to experimental data, specifically, Scatchard plots obtained using human cell lines. This paper demonstrates how the model correctly explains available experimental observations. It was estimated, for the first time, the value of the kinetic coefficients of IL2-IL2R complexes interaction in the cell membrane. Moreover, the number of IL2R components in different cell lines was also estimated. It was obtained a variable distribution in the number of IL2R components depending on the cell type and the activation state. Of most significance, the study predicts that not only the number of IL2Rα and IL2Rβ, but also the number of γc determine the capacity of the cell to capture and retain IL2 in signalling complexes. Moreover, it is also showed that different cells might use different pathways to bind IL2 as consequence of its IL2R components distribution in the membrane.

  8. 78 FR 32418 - Extension of the Designation of El Salvador for Temporary Protected Status

    Science.gov (United States)

    2013-05-30

    ... on the so-called Ring of Fire (an arc of fault lines circling the Pacific Basin), makes it vulnerable..., Illinois, Indiana, Kentucky, TPS El Salvador, P.O. Box Maine, Maryland, Massachusetts, 8635, Chicago, IL..., West Immigration Services, Attn: Virginia. TPS El Salvador, 131 S. Dearborn--3rd Floor Chicago, IL...

  9. 78 FR 36223 - Extension and Redesignation of Syria for Temporary Protected Status

    Science.gov (United States)

    2013-06-17

    ... children died in military offensives, sniper fire, attacks on protests, and massacres. Children have... Postal Service. Immigration Services, Attn: TPS Syria, P.O. Box 6943, Chicago, IL 60680-6943. You are... Syria, 131 S. Dearborn 3rd Floor, Chicago, IL 60603-5517. If you were granted TPS by an Immigration...

  10. Chicago classification criteria of esophageal motility disorders defined in high resolution esophageal pressure topography

    NARCIS (Netherlands)

    Bredenoord, A. J.; Fox, M.; Kahrilas, P. J.; Pandolfino, J. E.; Schwizer, W.; Smout, A. J. P. M.; Conklin, Jeffrey L.; Cook, Ian J.; Gyawali, C. Prakash; Hebbard, Geoffrey; Holloway, Richard H.; Ke, Meiyun; Keller, Jutta; Mittal, Ravinder K.; Peters, Jeff; Richter, Joel; Roman, Sabine; Rommel, Nathalie; Sifrim, Daniel; Tutuian, Radu; Valdovinos, Miguel; Vela, Marcelo F.; Zerbib, Frank

    2012-01-01

    Background The Chicago Classification of esophageal motility was developed to facilitate the interpretation of clinical high resolution esophageal pressure topography (EPT) studies, concurrent with the widespread adoption of this technology into clinical practice. The Chicago Classification has been

  11. Diffusion of Complete Streets policies Across US communities.

    Science.gov (United States)

    Moreland-Russell, Sarah; Eyler, Amy; Barbero, Colleen; Hipp, J Aaron; Walsh, Heidi

    2013-01-01

    Complete Streets policies guide planning in communities by making the transportation system accommodating to all users including vehicle drivers, pedestrians, and bicyclists, as well as those using public transportation. While the number of Complete Streets policies has increased over the past decade, no research has explored the factors attributing to the widespread diffusion of these policies. The purpose of this study was to apply concepts of the Diffusion of Innovation Theory to data related to Complete Streets policies in order to identify potential patterns and correlates. The main outcome of this study was policy adoption. Using the Diffusion of Innovation Theory and results from previous literature, we identified several factors that had the potential to affect the rate of Complete Streets policy diffusion: rural/urban status, state obesity rate, state funding for transportation, state obesity prevention funding, percentage of people who walk or bike to work in the state, presence of a state Complete Streets policy, and the number of bordering communities with Complete Streets policy. We used event history analysis as the main analysis method. Data from 49 community-level policies were analyzed, with a "community" defined as a city, a county, or a regional/Metropolitan Planning Organization. Three variables were significant predictors of Complete Streets policy adoption: state obesity rate (odds ratio [OR] = 1.465; confidence interval [CI] = 1.10-1.96) percentage of people who bike or walk to work in the state (OR = 1.726; CI = 1.069-2.79), and presence of a border community with a Complete Streets policy (OR = 3.859; CI = 1.084-13.742). Communities with Complete Streets policies varied in geographic and sociodemographic factors. Information about communities that are more likely to adopt a policy can be a tool for advocates and policy makers interested in this topic. Because adoption does not imply implementation, further research is needed to study

  12. Individuals with severely impaired vision can learn useful orientation and mobility skills in virtual streets and can use them to improve real street safety.

    Science.gov (United States)

    Bowman, Ellen Lambert; Liu, Lei

    2017-01-01

    Virtual reality has great potential in training road safety skills to individuals with low vision but the feasibility of such training has not been demonstrated. We tested the hypotheses that low vision individuals could learn useful skills in virtual streets and could apply them to improve real street safety. Twelve participants, whose vision was too poor to use the pedestrian signals were taught by a certified orientation and mobility specialist to determine the safest time to cross the street using the visual and auditory signals made by the start of previously stopped cars at a traffic-light controlled street intersection. Four participants were trained in real streets and eight in virtual streets presented on 3 projection screens. The crossing timing of all participants was evaluated in real streets before and after training. The participants were instructed to say "GO" at the time when they felt the safest to cross the street. A safety score was derived to quantify the GO calls based on its occurrence in the pedestrian phase (when the pedestrian sign did not show DON'T WALK). Before training, > 50% of the GO calls from all participants fell in the DON'T WALK phase of the traffic cycle and thus were totally unsafe. 20% of the GO calls fell in the latter half of the pedestrian phase. These calls were unsafe because one initiated crossing this late might not have sufficient time to walk across the street. After training, 90% of the GO calls fell in the early half of the pedestrian phase. These calls were safer because one initiated crossing in the pedestrian phase and had at least half of the pedestrian phase for walking across. Similar safety changes occurred in both virtual street and real street trained participants. An ANOVA showed a significant increase of the safety scores after training and there was no difference in this safety improvement between the virtual street and real street trained participants. This study demonstrated that virtual reality

  13. The changes of IL-8, IL-10, IL-12 and IgE in serum of patients with asthma

    International Nuclear Information System (INIS)

    Zhang Chao; Liu Deyi; Hou Guihua; Wang Haodan

    2002-01-01

    To evaluate the relationship and the clinical significance between the serum IL-8, IL-10, IL-12 and IgE in patients with asthma, the serum IL-8, IL-10 are measured by radioimmunoassay method and the serum IL-12, IgE by ELISA in 55 patients with asthma. The level of serum IL-8, IgE at stage of episode are significantly higher than that at stage of remission (P<0.01); the level of serum IL-10, IL-12 at stage of episode are significantly lower than that at stage of remission (P<0.01). Linear regression shows that the decrease of IL-12 relate to the increase of IgE. The results suggests that the change of the level of serum IL-8, IL-10, IL-12 and IgE could be a maker for the aggravation of asthma

  14. Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33 and asthma

    Directory of Open Access Journals (Sweden)

    Rahim Farahani

    2014-01-01

    Full Text Available Asthma is a reversible airway obstruction that is characterized by constriction of airway smooth muscle, hyper secretion of mucus, edema and airway hyper responsiveness (AHR, mucus secretion and thickening of the basement membrane underlying the airway epithelium. During the process of airway inflammation, complex interactions of innate and adaptive immune cells as well as structural cells and their cytokines have many important roles. It was believed that airway inflammation is orchestrated by allergen specific T helper (Th 2 cells, which recruit and accumulate in the lungs and produce a range of different effector cytokines. However, more recent studies have revealed the potential collaboration of other helper T cells and their cytokines in this process. Th17 cell may have a role in severe asthma and chronic obstructive pulmonary disease (COPD. Interleukin (IL-9-producing subset called Th9 cell, Th22 cells which primarily secrete IL-22, IL-13 and tumor necrosis factor-α and Th25 cells via producing IL-25 are believed to be important for initiating allergic reactions and developing airway inflammation. Cytokines are important in asthma and play a critical role in orchestrating the allergic inflammatory response, although the precise role of each cytokine remains to be determined. The aim of this review is to summarize the current knowledge about the possible roles of newly identified helper T cells derived cytokines (IL-9, 17, 22, 25 and IL-33 in asthma. The potential therapeutic applications emerging from the roles of these cytokines will be discussed as well.

  15. Street Choice Logit Model for Visitors in Shopping Districts

    Science.gov (United States)

    Kawada, Ko; Yamada, Takashi; Kishimoto, Tatsuya

    2014-01-01

    In this study, we propose two models for predicting people’s activity. The first model is the pedestrian distribution prediction (or postdiction) model by multiple regression analysis using space syntax indices of urban fabric and people distribution data obtained from a field survey. The second model is a street choice model for visitors using multinomial logit model. We performed a questionnaire survey on the field to investigate the strolling routes of 46 visitors and obtained a total of 1211 street choices in their routes. We proposed a utility function, sum of weighted space syntax indices, and other indices, and estimated the parameters for weights on the basis of maximum likelihood. These models consider both street networks, distance from destination, direction of the street choice and other spatial compositions (numbers of pedestrians, cars, shops, and elevation). The first model explains the characteristics of the street where many people tend to walk or stay. The second model explains the mechanism underlying the street choice of visitors and clarifies the differences in the weights of street choice parameters among the various attributes, such as gender, existence of destinations, number of people, etc. For all the attributes considered, the influences of DISTANCE and DIRECTION are strong. On the other hand, the influences of Int.V, SHOPS, CARS, ELEVATION, and WIDTH are different for each attribute. People with defined destinations tend to choose streets that “have more shops, and are wider and lower”. In contrast, people with undefined destinations tend to choose streets of high Int.V. The choice of males is affected by Int.V, SHOPS, WIDTH (positive) and CARS (negative). Females prefer streets that have many shops, and couples tend to choose downhill streets. The behavior of individual persons is affected by all variables. The behavior of people visiting in groups is affected by SHOP and WIDTH (positive). PMID:25379274

  16. Street Choice Logit Model for Visitors in Shopping Districts

    Directory of Open Access Journals (Sweden)

    Ko Kawada

    2014-07-01

    Full Text Available In this study, we propose two models for predicting people’s activity. The first model is the pedestrian distribution prediction (or postdiction model by multiple regression analysis using space syntax indices of urban fabric and people distribution data obtained from a field survey. The second model is a street choice model for visitors using multinomial logit model. We performed a questionnaire survey on the field to investigate the strolling routes of 46 visitors and obtained a total of 1211 street choices in their routes. We proposed a utility function, sum of weighted space syntax indices, and other indices, and estimated the parameters for weights on the basis of maximum likelihood. These models consider both street networks, distance from destination, direction of the street choice and other spatial compositions (numbers of pedestrians, cars, shops, and elevation. The first model explains the characteristics of the street where many people tend to walk or stay. The second model explains the mechanism underlying the street choice of visitors and clarifies the differences in the weights of street choice parameters among the various attributes, such as gender, existence of destinations, number of people, etc. For all the attributes considered, the influences of DISTANCE and DIRECTION are strong. On the other hand, the influences of Int.V, SHOPS, CARS, ELEVATION, and WIDTH are different for each attribute. People with defined destinations tend to choose streets that “have more shops, and are wider and lower”. In contrast, people with undefined destinations tend to choose streets of high Int.V. The choice of males is affected by Int.V, SHOPS, WIDTH (positive and CARS (negative. Females prefer streets that have many shops, and couples tend to choose downhill streets. The behavior of individual persons is affected by all variables. The behavior of people visiting in groups is affected by SHOP and WIDTH (positive.

  17. Health policy making for street children: challenges and strategies.

    Science.gov (United States)

    Abdi, Fatemeh; Saeieh, Sara Esmaelzadeh; Roozbeh, Nasibeh; Yazdkhasti, Mansoureh

    2017-08-17

    Background The phenomenon of street children is a bio-psychological and social issue that not only harms children, but also endangers the health of a society. In line with the national programs for the development and promotion of street children's health in Iran, health policy making and essential strategies for this group of children will be presented in this paper. This paper will discuss the main issues and challenges of street children's health and, also, health policy and guidelines for this population. Methods In this review study, the keywords; street children, health, challenges, policy, and health policy making were searched through PubMed, SID, Iranmedex, World Health Organization (WHO), Emro, the Cochran Library, Medline and Google scholar to collect data. The search resulted in 84 related resources from which 48 cases that were more relevant to this research and covered the issue more comprehensively, were used. All data published during 2002-2015 have been included in this paper. Results Key concepts including street children and their health, health policy, strategies to improve the health of street children, health policy approaches for street children, the WHO's strategies, and social support program for street children must be considered in the health policy making processes for street children, as precise identification of the relevant information makes planning more effective in health policy making for this group of children. Conclusion The phenomenon of street children is a growing problem in the world and it has turned into a serious concern in many countries including Iran. The findings of this study can be used for identifying necessary measures in order to use research outcomes more effectively in policy making processes and reforming street children's health policies in Iran.

  18. The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation.

    Directory of Open Access Journals (Sweden)

    Gaëlle Chognard

    Full Text Available IL-12 and IL-23 cytokines respectively drive Th1 and Th17 type responses. Yet, little is known regarding the biology of these receptors. As the IL-12 and IL-23 receptors share a common subunit, it has been assumed that these receptors are co-expressed. Surprisingly, we find that the expression of each of these receptors is restricted to specific cell types, in both mouse and human. Indeed, although IL-12Rβ2 is expressed by NK cells and a subset of γδ T cells, the expression of IL-23R is restricted to specific T cell subsets, a small number of B cells and innate lymphoid cells. By exploiting an IL-12- and IL-23-dependent mouse model of innate inflammation, we demonstrate an intricate interplay between IL-12Rβ2 NK cells and IL-23R innate lymphoid cells with respectively dominant roles in the regulation of systemic versus local inflammatory responses. Together, these findings support an unforeseen lineage-specific dichotomy in the in vivo role of both the IL-12 and IL-23 pathways in pathological inflammatory states, which may allow more accurate dissection of the roles of these receptors in chronic inflammatory diseases in humans.

  19. Whose Bay Street? Competing Narratives of Nassau's City Centre

    Directory of Open Access Journals (Sweden)

    Nona Patara Martin

    2009-05-01

    Full Text Available Bay Street has always been at the centre of commercial, cultural and political life in the Bahama Islands. It also acts as a gateway for millions of tourists who come to Nassau, the Bahamian capital, via cruise ships every year. Not surprisingly, Bahamians and non-Bahamians have widely divergent impressions of Bay Street. The need to accommodate the tourists who are critical to the Bahamian economy has meant that Bay Street, despite its deep social significance for Bahamians, has increasingly become a tourist space. With reference to the ‘sense of place’ and place attachment literature, this paper traces the transformation of Bay Street and attempts to tease out the most obvious tensions between the Bay Street that Bahamians experience and Bay Street as a port of call.

  20. Alcohol in urban streetscapes: a comparison of the use of Google Street View and on-street observation

    Directory of Open Access Journals (Sweden)

    Chris Clews

    2016-05-01

    Full Text Available Abstract Background Alcohol-related harm is a major global health issue, and controls on alcohol marketing are one intervention utilized by governments. This study investigated the use of Google Street View (GSV as a novel research method for collecting alcohol-related data in the urban environment. Methods The efficacy of GSV and on-street observation by observer teams was compared by surveying 400 m stretches of 12 streets in Wellington, the capital city of New Zealand. Data on alcohol sale, alcohol-related advertising, health promotion materials, regulatory information and visible alcohol consumption were collected. Results A total of 403 retailers with evidence of alcohol sales and 1161 items of alcohol-related communication were identified in on-street observation. Of the latter, 1028 items (89 % were for alcohol marketing and 133 (11 % were for alcohol-related health promotion and alcohol regulation. GSV was found to be a less sensitive tool than on-street observation with only 50 % of the alcohol venues identified and 52 % of the venue-associated brand marketing identified. A high degree of inter-observer reliability was generally found between pairs of observers e.g., for the detection of alcohol retail venues the intra-class correlation coefficient (ICC was 0.93 (95 % CI: 0.78 to 0.98 for on-street observation and 0.85 (95 % CI: 0.49 to 0.96 for using GSV. Conclusions GSV does not seem suitable for the comprehensive study of the influences on alcohol consumption in the urban streetscape. However, it may still have value for large, static objects in the environment and be more time efficient than traditional on-street observation measures, especially when used to collect data across a wide geographical area. Furthermore, GSV might become a more useful research tool in settings with better image quality (such as more ‘footpath views’ and with more regularly updated GSV imagery.

  1. Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma.

    Science.gov (United States)

    Agrawal, Swati; Townley, Robert G

    2014-02-01

    Asthma markedly diminishes quality of life due to limited activity, absences from work or school and hospitalizations. Patients with severe asthma which are not controlled despite taking effective therapy are most in need of new treatment approaches. IL-13 was demonstrated as 'central mediator of allergic asthma'. IL-13 has been implicated in the pathogenesis of asthma, idiopathic pulmonary fibrosis and COPD. IL-13 levels in the sputum and bronchial biopsy samples remain elevated in severe asthma despite the use of inhaled and systemic corticosteroids. Thus, IL-13 is a mediator involved in corticosteroid resistance. Periostin enhances profibrotic TGF-β signaling in subepithelial fibrosis associated with asthma. IL-13 induces bronchial epithelial cells to secrete periostin. Periostin may be a biomarker for Th2 induced airway inflammation. Lebrikizumab is a monoclonal antibody against IL-13. Lebrikizumab improved lung function in asthmatics who were symptomatic despite treatment with long acting beta agonist and inhaled corticosteroids and provided benefit in the treatment of severe uncontrolled asthma. Lebrikizumab block IL-13 signaling through the IL-13Rα1/IL-4Rα receptor. There was a larger reduction in FENO in the high periostin subgroup than in the low periostin subgroup (34.4 vs 4.3%). Serum CCL17, CCL13 and total IgE levels decreased in the lebrikizumab group.

  2. 75 FR 32778 - Change in Bank Control Notices; Acquisition of Shares of Bank or Bank Holding Companies

    Science.gov (United States)

    2010-06-09

    ... June 23, 2010. A. Federal Reserve Bank of Chicago (Colette A. Fried, Assistant Vice President) 230 South LaSalle Street, Chicago, Illinois 60690-1414: 1. John V. Tippmann, Sr., as an individual, and John V. Tippman, Sr.; John and Helen McCarthy; Richard and Sally Ley; John Tippman, Jr.; Patrick Tippman...

  3. 75 FR 38097 - Change in Bank Control Notices; Acquisition of Shares of Bank or Bank Holding Companies

    Science.gov (United States)

    2010-07-01

    ..., 2010. A. Federal Reserve Bank of Chicago (Colette A. Fried, Assistant Vice President) 230 South LaSalle Street, Chicago, Illinois 60690-1414: 1. John V. Tippmann, Sr., as an individual; John V. Tippmann, Sr.; John and Helen McCarthy; Richard and Sally Ley; John Tippmann, Jr.; Patrick Tippmann; and Brian and...

  4. 78 FR 77711 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-12-24

    ... Cook County Bush Temple of Music, 100 W. Chicago Ave., 800 N. Clark St., Chicago, 13001001 Stony Island... Independent city Waverly Main Street Historic District, Roughly bounded by E. 29th & E. 35th Sts., Old York Rd., Greenmount Ave., Baltimore (Independent City), 13001020 Nebraska Madison County Stubbs--Ballah House, 1000...

  5. 77 FR 25723 - Extension and Redesignation of Somalia for Temporary Protected Status

    Science.gov (United States)

    2012-05-01

    ... unlawfully in densely populated civilian neighborhoods and at times used civilians as ``shields'' to fire... applying for an initial Attn: TPS Somalia, P.O. Box registration: 6943, Chicago, IL 60680-6943. Non-U.S. Postal Delivery Service: USCIS, Attn: TPS Somalia, 131 S. Dearborn--3rd Floor, Chicago, IL 60603-5517. If...

  6. 75 FR 24734 - Extension of the Designation of Honduras for Temporary Protected Status and Automatic Extension...

    Science.gov (United States)

    2010-05-05

    ... for food production and the increased likelihood of flooding, landslides, and forest fires. All health... Service. Box 6943, Chicago, IL 60680- 6943. You are applying for the first time as U.S. Citizenship and a... 6943, Chicago, IL 60680-6943. You are using a Non-US Postal Service USCIS, Attn: TPS Honduras, 131...

  7. Into a Mapping of Copenhagen Street Lighting 2014

    DEFF Research Database (Denmark)

    Bülow, Katja; Asp, Claus; Kongshaug, Jesper

    LED lighting is a new lighting component in urban Spaces. How does LED lighting change the visual experience of a street, how did it use to be and how will it become? The book presents a mapping method in which an overview map of light sources in the Copenhagen streets is combined with a video...... recording and a series of photos from a route, whick goes through different city parts and types of streets. The mapping is done in the crucial changing fase, in which the street lighting in Copenhagen is a mix of previously used light sources and LED....

  8. IL-5 and IL-5 receptor in asthma

    Directory of Open Access Journals (Sweden)

    ATC Kotsimbos

    1997-12-01

    Full Text Available Eosinophils, along with mast cells are key cells involved in the innate immune response against parasitic infection whereas the adaptive immune response is largely dependent on lymphocytes. In chronic parasitic disease and in chronic allergic disease, IL-5 is predominantly a T cell derived cytokine which is particularly important for the terminal differentiation, activation and survival of committed eosinophil precursors. The human IL-5 gene is located on chromosome 5 in a gene cluster that contains the evolutionary related IL-4 family of cytokine genes. The human IL-5 receptor complex is a heterodimer consisting of a unique a subunit (predominantly expressed on eosinophils and a beta subunit which is shared between the receptors for IL-3 & GM-CSF (more widely expressed. The a subunit is required for ligand-specific binding whereas association with the beta subunit results in increased binding affinity. The alternative splicing of the alphaIL-5R gene which contains 14 exons can yield several alphaIL-5R isoforms including a membrane-anchored isoform (alphaIL-5Rm and a soluble isoform (alphaIL-5Rs. Cytokines such as IL-5 produce specific and non-specific cellular responses through specific cell membrane receptor mediated activation of intracellular signal transduction pathways which, to a large part, regulate gene expression. The major intracellular signal transduction mechanism is activation of non-receptor associated tyrosine kinases including JAK and MAP kinases which can then transduce signals via a novel family of transcriptional factors named signal transducers and activators of transcription (STATS. JAK2, STAT1 and STAT 5 appear to be particularly important in IL-5 mediated eosinophil responses. Asthma is characterized by episodic airways obstruction, increased bronchial responsiveness, and airway inflammation. Several studies have shown an association between the number of activated T cells and eosinophils in the airways and abnormalities

  9. Chicago Business Leadership and School Reform. Supporting Leaders for Tomorrow, Occasional Paper #3.

    Science.gov (United States)

    Bednarik, David

    Chicago's city leaders, unlike other city leaders, are going after fundamental and radical restructuring of the nation's third largest school system, but have found that it is hard to achieve. This paper provides a snapshot of the growing political involvement of Chicago's business leadership with the city's troubled school system. The need for…

  10. 78 FR 23220 - Foreign-Trade Zone 22-Chicago, Illinois, Authorization of Production Activity, Abbott...

    Science.gov (United States)

    2013-04-18

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-91-2012] Foreign-Trade Zone 22--Chicago, Illinois, Authorization of Production Activity, Abbott Laboratories, Inc., AbbVie, Inc. (Pharmaceutical Production), North Chicago, Illinois, Area On December 14, 2012, Abbott Laboratories, Inc., and AbbVie, Inc...

  11. The Chicago Landscape of Career and Technical Education. Feature on Research and Leadership. Vol. 2, No. 1

    Science.gov (United States)

    Owens, Devean R.; Welton, Anjalé D.

    2016-01-01

    In this brief, Owens and Welton provide an introductory overview of career and technical education (CTE) programs in both Chicago Public Schools (CPS) and the City Colleges of Chicago (CCC). They report that the State of Illinois, and the City of Chicago in particular, have some of the highest unemployment rates in the country for youth ages 16 to…

  12. POLE-LIKE STREET FURNITURE DECOMPOSTION IN MOBILE LASER SCANNING DATA

    OpenAIRE

    Li, F.; Oude Elberink, S.; Vosselman, G.

    2016-01-01

    Automatic semantic interpretation of street furniture has become a popular topic in recent years. Current studies detect street furniture as connected components of points above the street level. Street furniture classification based on properties of such components suffers from large intra class variability of shapes and cannot deal with mixed classes like traffic signs attached to light poles. In this paper, we focus on the decomposition of point clouds of pole-like street furniture. A nove...

  13. Street canyon ventilation control by proper planning and development

    Directory of Open Access Journals (Sweden)

    Balakin Vladimir Vasil'evich

    2014-05-01

    Full Text Available The objective of street canyon ventilation control in major streets is a tool of air pollution prevention in them, protection of housing areas from excessive wind or preservation and intensification of existing wind speed in case of insufficient ventilation. The maximum permissible concentration of car exhaust pollutants with wind speed within comfortable and permissible values by physiological and hygienic criteria, are ensured as from 40 to 70 % of thoroughfares in major cities. The dependence of air pollution level on wind speed is comparable to its dependence on traffic intensity and ratio of buildings height (H to street width. But one has to take into account that, if the wind blows across the street, vortices form within the street canyon, which results in higher concentration of car exhaust pollutants near the downwind buildings. The objective of this work is to find the functional dependences of wind speed in a major street on its width and density of buildings, and also to find out which street configurations are favorable for formation of closed air circulation within it, resulting in insufficient aeration. The experimental research was done on a site for large-scale modeling of built-up urban territory, using cup anemometers. The coefficients of dependence of wind speed within a street on the types of buildings and on the street width were obtained. Characteristics of street layouts for control of aeration were determined. Building density rates for maximizing or optimizing the wind speed were determined. Street layouts are considered where stable vortices form between the buildings. For example, vortices within the street canyon’s cross-section appear when buildings squarish in ground plan situated far apart are replaced by oblong ones with the minimum allowed intervals of 15 meters between them (for 5-storeyed buildings; or intervals equal to the buildings’ height, or where the buildings are long and close together. With

  14. Allergic Rhinitis and Its Relationship with IL-10, IL-17, TGF-β, IFN-γ, IL 22, and IL-35

    Directory of Open Access Journals (Sweden)

    P. Bayrak Degirmenci

    2018-01-01

    Full Text Available Background. We aimed in our study to research the role of new cytokines such as IL-35, IL-22, and IL-17 that may form a target for novel treatment approaches. Methods. IL-10, IL-17, TGF-β, IFN-γ, IL-22, and IL-35 serum levels of allergic rhinitis (AR patients were measured using ELISA method. Allergic sensitization was demonstrated by the skin prick test. Patients only with olive tree sensitivity were evaluated for seasonal AR (SAR. Patients only with mite sensitivity were included in the study for perennial AR (PAR. AR clinic severity was demonstrated by the nasal symptom scores (NSS. Results. In total, 65 AR patients (patient group, having 31 PAR and 34 SAR patients, and 31 healthy individuals (control group participated in the study. Cytokine levels between the patient group and the control group were compared; IL-17 (p=0.038, IL-22 (p=0.001, and TGF-β (p=0.031 were detected as high in the patient group, and IFN-γ (p<0.001 was detected as low in the patient group. When correlation analysis was made between age, gender, prick test result, NSS, AR duration, and cytokine levels in the patient group, a negative correlation was detected only between IFN-γ (p=0.032/r=−0.266 level and NSS. Conclusions. Accompanied by the literature information, these results made us think that T cell subgroups and cytokines have an important role in AR immunopathogenesis. It is thought that future studies to be conducted relating to this subject will form new targets in treatment.

  15. Street children of India -- a glimpse.

    Science.gov (United States)

    Nigam, S

    1994-01-01

    In India, 90% of street children are working children with regular family ties who live with their families, but are on the streets due to poverty and their parents' unemployment. The remaining 10% are either working children with few family ties who view the streets as their homes or abandoned and neglected children with no family ties. The National Policy for Children established in 1974 emphasizes the provision of equal opportunities for the development to all children during their growing years. Policy stresses programs to maintain, educate, and train destitute children and orphans. Policy is also to protect children against neglect, cruelty, and exploitation, but this is only on paper. An UNICEF study found that almost 40,000 children die every day in developing countries, 25% of whom are in India. Studies in some major cities indicate that the street children in India are of moderate health status, suffering from various chronic diseases and undernourishment. They are deprived of all health programs, but seem to prefer government hospitals in case of dire need. Street children often have to pay for water. Almost 97% in Calcutta, 99% in Bangalore, and 90% in Madras reported having no access to toilet and bathing facilities; 83% in Kanpur, however, had access to such facilities. Nothing has been heard in recent years of the National Children's Board established in 1975. Apparently the board has gradually waned. Various schemes were planned in 1992 by the Union Welfare Ministry in association with UNICEF. Extending extra health facilities, establishing nutrition programs, providing vocational training, protecting children from abuse, distributing dry-food polypacks, providing night shelters, providing ration cards, and creating bathing and toilet facilities would go far in improving the quality of life and the future of street children in India.

  16. 75 FR 71744 - Fifth Street Finance Corp., et al.; Notice of Application

    Science.gov (United States)

    2010-11-24

    ... Street Finance Corp., et al.; Notice of Application November 18, 2010. AGENCY: Securities and Exchange... Street Finance Corp. (``Fifth Street''), Fifth Street Management LLC, Fifth Street Mezzanine Partners IV... regulated as a business development company (``BDC'') under the Act. Fifth Street is a specialty finance...

  17. Getting to the CORE of the Chicago Teachers’ Union Transformation

    Directory of Open Access Journals (Sweden)

    Peter Brogan

    2014-05-01

    Full Text Available This article draws on a comparative study of urban change and rank-and-file teacher rebellion in New York City and Chicago, to explore the contemporary dynamics of what Jamie Peck (2013 calls “austerity urbanism” and its relationship to a rebirth of a social justice, grassroots teacher unionism in US urban centres. Tracing the trajectories of one group of rank-and-file teacher dissidents in Chicago, it argues that municipal unions are uniquely situated to lead the fight against austerity urbanism and the crisis tendencies of contemporary capitalism. To do this, however, trade unions will need to be reinvented and a different form of working class politic forged, grounded both in and outside of the trade union movement. Only then may we see organized labour in North America contribute to a movement for radical and systemic change, which is key to building a more socially just urbanism and society more broadly. The case of the Chicago teachers is highly instructive for activists, both inside and outside of the North American labour movement.

  18. 78 FR 21603 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2013-04-11

    ... April 26, 2013. A. Federal Reserve Bank of Chicago (Colette A. Fried, Assistant Vice President) 230 South LaSalle Street, Chicago, Illinois 60690-1414: 1. MBG Investors I, LP, Mexico City, Mexico, and its... Pablo del Valle Perochena, Ignacio del Valle Ruiz and Adolfo del Valle Ruiz, all of Mexico City, Mexico...

  19. A Study on Evaluation for Street Space using AHP Method

    OpenAIRE

    小塚, みすず; 許, 彦; 川本, 義海; 本多, 義明

    2004-01-01

    Street space is an important public area which forms the framework of city space. In addition, from the view of the traffic functions, street space also plays a role to support people's activities performed in city. This paper examines the evaluations of street space among the cities of Fukui (Japan), Toyota (Japan) and Suzhou (China). Therefore, a questionnaire has been carried out and actual conditions of street space are grasped. In addition street functions were evaluated with the AHP met...

  20. "Street Love": How Street Life Oriented U. S. Born African Men Frame Giving Back to One Another and the Local Community

    Science.gov (United States)

    Payne, Yasser Arafat; Hamdi, Hanaa A.

    2009-01-01

    This Participatory Action Research (PAR) project worked with four active street life oriented U. S. born African men, to document how a community sample of street life oriented U. S. born African men between the ages of 16-65, frame and use "street life" as a Site of Resiliency (Payne, Dissertation, 2005; "Journal of Black Psychology" 34(1):3-31,…

  1. The (Street) Art of Resistance

    DEFF Research Database (Denmark)

    Awad, Sarah H.; Wagoner, Brady; Glaveanu, Vlad Petre

    2017-01-01

    This chapter focuses on the interrelation between resistance, novelty and social change We will consider resistance as both a social and individual phenomenon, a constructive process that articulates continuity and change and as an act oriented towards an imagined future of different communities....... In this account, resistance is thus a creative act having its own dynamic and, most of all, aesthetic dimension. In fact, it is one such visibly artistic form of resistance that will be considered here, the case of street art as a tool of social protest and revolution in Egypt. Street art is commonly defined...... in sharp contrast with high or fine art because of its collective nature and anonymity, its different kind of aesthetics, and most of all its disruptive, ‘anti-social’ outcomes. With the use of illustrations, we will argue here that street art is prototypical of a creative form of resistance, situated...

  2. 78 FR 49684 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2013-08-15

    ...-AA00 Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago... the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago... the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago...

  3. Street children: “Running from” or “running to”?

    Directory of Open Access Journals (Sweden)

    J. le Roux

    1997-03-01

    Full Text Available The street child phenomenon presents a complex issue resulting from a diversity of integrated factors. The problem should therefore preferably be explained and addressed holistically. A search of available literature on street children clearly indicates that street children per se are not the primary problem. The phenomenon o f street children is merely a symptom of a problem underlying the intolerable situation of these children's family and community lives. In this article it is explained that the street child phenomenon is thus symptomatic of contemporary twentieth century conditions. "Running from " and “running to " are in fact intereffective tendencies or reactions to a complicated polarised society: two sides of a common coin.

  4. Designing safe and inclusive streets in India | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    17 nov. 2016 ... Safe streets play a crucial role in enabling livelihoods, mobility, and access to services. In fast-growing Indian cities such as Ahmedabad, streets are also the site of conflict. With incomes and vehicle ownership on the rise, traffic has replaced people as the central point of street design. Vehicle-focused street ...

  5. School Me, School Me Not, Street Me, Street Me Not…

    DEFF Research Database (Denmark)

    Gravesen, David Thore; Frostholm, Peter Hornbæk

    School Me, School Me Not, Street Me, Street Me Not… (1099) David Thore Gravesen, Peter Hornbæk Frostholm ECER 2016, 14. Communities, Families and Schooling in Educational Research, Session: 14 SES 10 A When picking leaves of a marguerite, whilst doing the “she loves me, she loves me not” game, you....... Obviously, the skaters attend the site to skate. But also other, more vulnerable groupings, use the site to socialize, meet peers and perhaps escape an unreliable and risky family arena. One particular group, the self-named Thugz, primarily formed around a number of young boys with non-Danish ethnic...... milieu. With a criminal gang-like behavior (Hoeben & Weerman 2013; Hviid 2007; Rasmussen 2012) involving petty crime and violence, one would think the group members would be indifferent towards their schooling and future careers. This was not the case. The informants proved to be very aware...

  6. Improving urban visibility through fractal analysis of street edges: The case of John Evans Atta Mills High Street in Accra, Ghana

    Directory of Open Access Journals (Sweden)

    R.A. Oppong

    2017-06-01

    Full Text Available Streets are a representation of cities, and the image of a city is a reflection of its home country. Although attempts to ensure harmonious spatial and environmental development in Ghanaian settlements date back to the colonial era, these efforts have minimal physical manifestation in the urban fabric of the city of Accra. The Independence Arch of Ghana, an important landmark in the urban fabric and history of Accra, lacks the striking vista and approach it deserves. This paper introduces the use of fractal analysis of street edges to understand the characteristics of the John Evans Atta Mills (JEAM High Street for developing recommendations to improve visibility along its stretch and the overall image of the city. The box-counting method with visual survey was used in research. The pertinent questions this paper seeks to address are as follows: What factors affect the visibility and imageability of JEAM High Street? What design aspects should be considered to improve urban visibility along JEAM High Street? What is the link of fractals to urban design and architecture? The paper recommends various design considerations and qualities to improve the urban visibility and imageability of JEAM High Street.

  7. 76 FR 65609 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2011-10-24

    ... Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship Canal... Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal, Chicago... INFORMATION: The Coast Guard will enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake...

  8. 78 FR 36091 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2013-06-17

    ... Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal... the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago...

  9. 76 FR 63199 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2011-10-12

    ... Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal...

  10. Complementary and alternative medicine use for arthritis pain in 2 Chicago community areas.

    Science.gov (United States)

    Feinglass, Joe; Lee, Chin; Rogers, Michelle; Temple, Leslie Mendoza; Nelson, Cynthia; Chang, Rowland W

    2007-01-01

    To compare the use of complementary and alternative medicine (CAM) for arthritis between 2 ethnically distinct metropolitan Chicago community areas. A telephone interview survey of adults age 45 years or above living in North (88.9% white) or South (79.7% African American) areas. Of 763 respondents, 405 reported arthritis or chronic joint symptoms and were asked about use and satisfaction with 7 CAM therapies. Differences between areas were compared with population-weighted tests; multiple logistic regression was used to analyze the likelihood of CAM use controlled for demographics, behavioral risk factors, and arthritis severity. South Chicago respondents had a higher prevalence and more severe arthritis symptoms such as mean joint pain and more functional limitations. Use of CAM therapy by South Chicago respondents, most commonly massage and relaxation techniques, was 10% greater than North Chicago respondents (61.5% to 51%) but this was not significantly different. Among CAM users, South Chicago respondents reported higher satisfaction with 6 of the 7 CAM therapies and greater future interest in CAM therapies. Poor overall health status (P=0.03), arthritis pain (P=0.005), and concomitant use of prescription medications (P=0.03) were the only significant predictors of CAM use. Although there were only small differences in overall CAM use by area, older residents of largely African American communities were enthusiastic users of relaxation, massage, and nutritional and dietary techniques. CAM modalities could be important adjuncts to traditional medical treatment of arthritis pain for minority communities.

  11. La historia olvidada de las mujeres de la Escuela de Chicago

    Directory of Open Access Journals (Sweden)

    Silvia García Dauder

    2010-01-01

    Full Text Available Si bien muchos manuales sitúan parte de los orígenes de la historia de la sociología en la Escuela de Chicago con Mead, Dewey, Thomas, etc., pocos son los que recogen los nombres, los retratos y los trabajos de las mujeres que desde la Universidad de Chicago aunaron teoría, investigación y activismo, contribuyendo al afianzamiento de las ciencias sociales dentro y fuera de la academia. Este artículo analiza la obra colectiva de las mujeres de la Escuela de Chicago desde posiciones interdisciplinares y desde la confusión cienciareforma en el contexto de EE.UU. de principios del siglo XX. Para ello recoge a modo de muestra sus trabajos publicados en la American Journal of Sociology desde su número inaugural hasta 1920. Con ello se pretende reflexionar sobre las políticas de género y reconocimiento dentro de las ciencias sociales y sobre la supuesta neutralidad de su historia.

  12. Diversity of contexts in drug use among street adolescents.

    Science.gov (United States)

    Goncalves de Moura, Yone; van der Meer Sanchez, Zila; Noto, Ana Regina

    2010-09-01

    In this study we aimed to investigate through ethnographic methods the different contexts of drug use by street adolescents in Sao Paulo, Brazil. Participant observations and semistructured interviews were performed at 11 major points of adolescent concentration in the streets of the city and in 10 care institutions. The sample was composed of 17 adolescents between 12 and 17 years of age. Data showed diverse patterns of drug use distributed by geographic situation and street circumstances. Observations were grouped into three main contexts: (a) immersion: greater intensity of drug use associated with greater involvement in the street culture; (b) surface: less drug use associated with family closeness; and (c) alternative-migratory: greater involvement with drug trafficking and prostitution associated with less family closeness and street culture. The drug use patterns varied in accordance with the diversity of street situations. Therefore, the peculiarities of each context should be taken into consideration in the development of social/ health policies.

  13. Asian longhorned beetle (ALB) Anoplophora gabripennis: advancements in the eradication program

    Science.gov (United States)

    Christine Markham; Joe Gittleman; Tom Denholm; Clint. McFarland

    2011-01-01

    Current detections of Asian longhorned beetle (ALB): August 1996--Brooklyn, NY, later detected on Long Island and in other parts of New York City; July 1998--Chicago, IL; October 2002--Jersey City, NJ; August 2004--Carteret, NJ; August 2008--Worcester, MA. Declared eradication of ALB infestations: April 2008--Chicago, IL, and Jersey City, NJ. Currently regulated for...

  14. THE DEVELOPMENT OF STREET PATTERNS IN ISRAELI CITIES

    Directory of Open Access Journals (Sweden)

    Itzhak OMER

    2015-12-01

    Full Text Available Street patterns of Israeli cities were investigated by comparing three time periods of urban development: (I the late 19th century until the establishment of the state of Israel in 1948; (II 1948 until the 1980s; and (III the late 1980s until the present. These time periods are related respectively to the pre-modern, modern and late-modern urban planning approach. Representative urban street networks were examined in selected cities by means of morphological analysis of typical street pattern properties: curvature, fragmentation, connectivity, continuity and differentiation. The study results reveal significant differences between the street patterns of the three examined periods in the development of cities in Israel. The results show clearly the gradual trends in the intensification of curvature, fragmentation, complexity and hierarchical organization of street networks as well as the weakening of the network's internal and external connectivity. The implications of these changes on connectivity and spatial integration are discussed with respect to planning approaches.

  15. THE DEVELOPMENT OF STREET PATTERNS IN ISRAELI CITIES

    Directory of Open Access Journals (Sweden)

    Itzhak OMER

    2016-07-01

    Full Text Available Street patterns of Israeli cities were investigated by comparing three time periods of urban development: (I the late 19th century until the establishment of the state of Israel in 1948; (II 1948 until the 1980s; and (III the late 1980s until the present. These time periods are related respectively to the pre-modern, modern and late-modern urban planning approach. Representative urban street networks were examined in selected cities by means of morphological analysis of typical street pattern properties: curvature, fragmentation, connectivity, continuity and differentiation. The study results reveal significant differences between the street patterns of the three examined periods in the development of cities in Israel. The results show clearly the gradual trends in the intensification of curvature, fragmentation, complexity and hierarchical organization of street networks as well as the weakening of the network's internal and external connectivity. The implications of these changes on connectivity and spatial integration are discussed with respect to planning approaches.

  16. Socio - demographic characteristics of child street vendors in Nnewi ...

    African Journals Online (AJOL)

    Background: Involvement of children in street trading is inimical, contrary to the Rights of the Child, and threatens holistic child development. Objective: To describe the sociodemographic characteristics of child street vendors in Nnewi. Method: A cross-sectional questionnaire survey of children selling wares on the streets of ...

  17. Socio-demographic characteristics of street children in rural ... - Ibadan

    African Journals Online (AJOL)

    15.0%), part-time driving (9.5%) and car washing (5.0%) were the commonest types of work. Of those still schooling, 41.6% had no form of part-time work on the streets. None of the street children lived on the street with 65% still living with parents.

  18. Space Livability of Street Vendors in Simpang Lima Public Space, Semarang

    Science.gov (United States)

    Widjajanti, R.; Wahyono, H.

    2018-02-01

    Street vendors in Semarang have been growing rapidly and uncontrolled. They always use public space such as public roads, sidewalks, parks and fields as trading locations. The street vendors’ activities in the public space are considered as the cause of declining on environmental quality and aesthetics of the city. All these years, the government often evicted the street vendors than organized and provides adequate space for them. As one of the actual urban activities, the street vendors’ activities should be accommodated by the government and the location for them is managed in the urban spatial plan. Street vendors need spaces which livable and suitable to their activities’ requirements, has a relationship with users (street vendors’ doers and consumers) and the activities of street vendors themselves. Research on the aspect of space for street vendors is still less in quantity, whereas space for them is an urgent matter for the government in managing their activities. This study aims to identify the livability of space based on the street vendors’ behavior in their location. This research used descriptive quantitative method with questionnaires and GIS as the mapping tool for street vendors’ location. The result of the research shows that the livability of street vendor space is based on the activity of street vendors (type of merchandise, trading places’ size, trade place assessment, space dimension, trading time, duration and period) and space conditions (access, natural elements, safety and parking space).

  19. [Street Outreach Offices: visibility, invisibility, and enhanced visibility].

    Science.gov (United States)

    Hallais, Janaína Alves da Silveira; Barros, Nelson Filice de

    2015-07-01

    This article discusses care for street people from a socio-anthropological perspective, using participant observation conducted with a team from a street outreach project. Based on observations, street people are historically viewed as marginal and rarely obtain access to health services, thus making them invisible to the Brazilian Unified National Health System. Brazil's National Policy for the Homeless provides for their access to health care, but such care is not always guaranteed in practice, because health services and professionals have little experience in dealing with homeless persons. The study concludes that enhanced visibility is needed to ensure care for people living on the street, establishing a therapeutic bond that deconstructs stigmatizing practice.

  20. Il nucleo terrestre: il cuore magnetico della Terra

    OpenAIRE

    De Santis, A.

    2006-01-01

    Il campo magnetico terrestre è una proprietà intrinseca del nostro pianeta e di altri oggetti del sistema solare. Il Sole stesso possiede un forte campo magnetico che si inverte quasi ciclicamente ogni 10-11 anni; tale comportamento è visibile attraverso la medesima ciclicità delle macchie solari che denotano sulla superficie l’intensa attività magnetica della nostra stella. Il campo magnetico terrestre è importantissimo per la vita sulla Terra. Esso protegge il pianeta dalle p...

  1. A social work study on family patterns and street children

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Iravani

    2014-06-01

    Full Text Available This paper presents a social work study on relationship between various family characteristics and street children in rural area as well as city of Esfahan, Iran. The proposed study selects a sample of 150 street children, 75 from city and 75 from rural area, and using some statistical tests verifies the effects of three factors including family income, place of residency and family size on street children. The results indicate that the city residence had more street children than rural residence did. In addition, there was a meaningful difference between the number of street children in low-income families and high-income families. Finally, the survey results indicate that big size families more likely suffered from street children than low size families did.

  2. IL-17A, IL-17RC polymorphisms and IL17 plasma levels in Tunisian patients with rheumatoid arthritis

    Science.gov (United States)

    Chahbi, Mayssa; Haouami, Youssra; Sfar, Imen; Abdelmoula, Leila; Ben Abdallah, Taieb; Gorgi, Yousr

    2018-01-01

    Background Interleukin-17 (IL-17), a cytokine mainly secreted by Th17 cells, seems to play a significant role in the pathogenesis of rheumatoid arthritis (RA). Functional genetic polymorphisms in IL-17 and its receptor genes can influence either qualitatively or quantitatively their functions. Therefore, we aimed to study the impact of IL17-A and IL17RC polymorphisms on plasma level of IL-17 and RA susceptibility and severity. Methods In this context, IL-17A*rs2275913 and IL-17RC*rs708567 polymorphisms were investigated together with the quantification of IL17 plasma level in 115 RA patients and 91 healthy control subjects matched in age, sex and ethnic origin. Results There were no statistically significant associations between IL-17A and IL-17RC studied polymorphisms and RA susceptibility. In contrast, IL-17A plasma levels were significantly higher in patients (55.07 pg/ml) comparatively to controls (4.75 pg/ml), p<10E-12. A ROC curve was used to evaluate the performance of plasma IL-17 in detecting RA. Given 100% specificity, the highest sensitivity of plasma IL-17A was 61.7% at a cut-off value of 18.25 pg/ml; p < 10E-21, CI = [0.849–0.939]. Analytic results showed that the IgM-rheumatoid factor and anti-CCP antibodies were significantly less frequent in patients with the IL-17RC*A/A genotype than those carrying *G/G and *G/A genotypes; p = 0.013 and p = 0.015, respectively. Otherwise, IL-17 plasma levels’ analysis showed a significant association with the activity of RA (DAS28≥5.1 = 74.71 pg/ml vs. DAS28<5.1 = 11.96 pg/ml), p<10E-6. Conclusion IL-17A*rs2275913 (G/A) and IL-17RC*rs708567 (G/A) polymorphisms did not seem to influence RA susceptibility in Tunisian population. This result agrees with those reported previously. Plasma IL-17A level seems to be predictive of severe RA occurrence. PMID:29584788

  3. Genetic polymorphism of interleukin-1A (IL-1A), IL-1B, and IL-1 receptor antagonist (IL-1RN) and prostate cancer risk.

    Science.gov (United States)

    Xu, Hua; Ding, Qiang; Jiang, Hao-Wen

    2014-01-01

    We aimed to investigate the associations between polymorphisms of interleukin-1A (IL-1A), IL-1B, and IL-1 receptor antagonist (IL-1RN) and prostate cancer (PCa) risk. A comprehensive search for articles of MEDLINE and EMBASE databases and bibliographies of retrieved articles published up to August 3, 2014 was performed. Methodological quality assessment of the trials was based on a standard quality scoring system. The meta-analysis was performed using STATA 12.0. We included 9 studies (1 study for IL-1A, 5 studies for IL-1B, and 3 studies for IL-1RN), and significant association was found between polymorphisms of IL-1B-511 (rs16944) as well as IL-1B-31 (rs1143627) and PCa risk. IL-1B-511 (rs16944) polymorphism was significantly associated with PCa risk in homozygote and recessive models, as well as allele contrast (TT vs CC: OR, 0.74; 95%CI, 0.58-0.94; P=0.012; TT vs TC+CC; OR, 0.79; 95%CI, 0.63-0.98; P=0.033; T vs C: OR, 0.86; 95%CI, 0.77-0.96; P=0.008). The association between IL-1B-31 (rs1143627) polymorphism and PCa risk was weakly significant under a heterozygote model (OR, 1.35; 95%CI, 1.00-1.80; P=0.047). Sequence variants in IL-1B-511 (rs16944) and IL-1B-31 (rs1143627) are significantly associated with PCa risk, which provides additional novel evidence that proinflammatory cytokines and inflammation play an important role in the etiology of PCa.

  4. Risk behaviour of street children in Colombo.

    Science.gov (United States)

    Senaratna, B C V; Wijewardana, B V N

    2012-09-01

    Sri Lankan street children live in insecure and disadvantaged environments and have disrupted and poorly functioning families resulting in their poor socialisation. In this backdrop they are at high risk of adopting delinquent and antisocial behaviour and becoming victims of abuse. Despite recognition of this as a social problem, an in-depth exploration of their behaviour and its correlates has not been attempted. To describe risk behaviour among street children in Colombo city and the determinants of such behaviour. A cross sectional qualitative study in Colombo Fort, Pettah, Slave Island, and Maradana areas was conducted using focus group discussions (FGDs) with street children and semi-structured interviews (SSIs) with street children and key informants in their environment. Data generated were used to profile 283 children identified through referral sampling. An observation study was conducted to validate data generated through FGDs and SSIs. Semi-structured questionnaires, a moderator guide, an interviewer-administered questionnaire, and an observational checklist were used for SSIs, FGDs, profiling, and observational study, respectively. Majority of street children were boys and were aged 14 years or less. Nearly 18% lived alone without a guardian. Two thirds had never enrolled in a school. Many children were used for begging, neglecting their health vulnerabilities. Occupational risk behaviour included heavy manual labour, transportation and sale of illicit alcohol and narcotics, robbing/pick-pocketing, commercial sex work, and pimping. Recreational risk behaviour included abuse of alcohol/narcotics, smoking, sexual promiscuity, and patronising commercial sex workers. Increased awareness and strategies are required to minimise threats to street children and society.

  5. Analyzing Thermal Characteristics of Urban Streets Using a Thermal Imaging Camera: A Case Study on Commercial Streets in Seoul, Korea

    Directory of Open Access Journals (Sweden)

    Sugie Lee

    2018-02-01

    Full Text Available Due to continuing city growth and global warming over the past decades, urban heat island (UHI effects, referring to the phenomena wherein the ambient air temperatures in cities are higher than those in rural areas, have become a serious threat to urban populations. Impervious surfaces, buildings with low-albedo materials, and a lack of vegetated areas are the major causes of poor urban thermal environments, particularly during the summer. Previous research has focused primarily on the thermal characteristics of individual building units. Few studies consider the impact of the street-scale thermal environments on the surface temperature, which affects pedestrian thermal comfort. The purpose of this study is to analyze the thermal characteristics of various physical elements on urban streets using thermal imaging cameras, and present policy implications for improving pedestrian thermal comfort. This study examines street-scale thermal environments of three major commercial streets: Garosu road, Serosu road, and Narosu road, in Seoul, Korea. This study conducted field measurements both during the day and the night in June 2017 in order to investigate changes in the urban surface temperatures across time. The results show that street trees are the most effective mitigation element for reducing surface temperatures. With regard to building use types, the highest surface temperatures are typically measured near restaurant buildings. Building façades that are dark-colored or partially covered with a metal contribute to high surface temperatures. Similarly, the temperatures of artificial turf or wooden decks on urban streets are also significantly high during the daytime. The thermal characteristics of various urban street elements should be considered to reduce the surface temperature and mitigate the urban heat island effect.

  6. 77 FR 4844 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Order Approving a...

    Science.gov (United States)

    2012-01-31

    ... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-66235; File No. SR-CBOE-2011-114] Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Order Approving a Proposed Rule Change Relating to Complex Order Processing in Hybrid 3.0 Classes January 25, 2012. I. Introduction On November 29, 2011, the Chicago Board Options...

  7. Competition for the Elements of the City Environment for Irkutsk’s Public Spaces: Street Furniture, Street Design

    Directory of Open Access Journals (Sweden)

    Tatyana Danilova

    2016-10-01

    Full Text Available The article reviews the contest «Street furniture. Street design», which was held this summer by manufacturing company «PalpNord», International research laboratory of study and design of the urban environment «Urban Planning School» and the Union of Architects of Russia. The winners and their projects are also listed in the article.

  8. Mapping Urban Land Use at Street Block Level Using OpenStreetMap, Remote Sensing Data, and Spatial Metrics

    Directory of Open Access Journals (Sweden)

    Taïs Grippa

    2018-06-01

    Full Text Available Up-to-date and reliable land-use information is essential for a variety of applications such as planning or monitoring of the urban environment. This research presents a workflow for mapping urban land use at the street block level, with a focus on residential use, using very-high resolution satellite imagery and derived land-cover maps as input. We develop a processing chain for the automated creation of street block polygons from OpenStreetMap and ancillary data. Spatial metrics and other street block features are computed, followed by feature selection that reduces the initial datasets by more than 80%, providing a parsimonious, discriminative, and redundancy-free set of features. A random forest (RF classifier is used for the classification of street blocks, which results in accuracies of 84% and 79% for five and six land-use classes, respectively. We exploit the probabilistic output of RF to identify and relabel blocks that have a high degree of uncertainty. Finally, the thematic precision of the residential blocks is refined according to the proportion of the built-up area. The output data and processing chains are made freely available. The proposed framework is able to process large datasets, given that the cities in the case studies, Dakar and Ouagadougou, cover more than 1000 km2 in total, with a spatial resolution of 0.5 m.

  9. Cord Blood Cells Responses to IL2, IL7 and IL15 Cytokines for mTOR Expression

    Directory of Open Access Journals (Sweden)

    Anahita Mohammadian

    2017-04-01

    Full Text Available Purpose: Mammalian target of rapamycin (mTORis important in hematopoiesis and affect cell growth,differentiation and survival. Although previous studies were identified the effect of cytokines on the mononuclear cells development however the cytokines effect on mTOR in cord blood mononuclear cells was unclear. The aim of this study was to evaluate mTOR expression in cord blood mononuclear and cord blood stem cells (CD34+ cells in culture conditions for lymphoid cell development. Methods: Isolation of The mononuclear cells (MNCs from umbilical cord blood were done with use of Ficollpaque density gradient. We evaluated cultured cord blood mononuclear and CD34+ cells in presece of IL2, IL7 and IL15 at distinct time points during 21 days by using flow cytometry. In this study, we presented the role of IL2, IL7 and IL15 on the expression of mTOR in cord blood cells. Results: mTOR expression were increased in peresence of IL2, IL7 and IL15 in day 14 and afterword reduced. However in persence of IL2 and IL15 expression of mTOR significantly reduced. mTOR expression in CD34+ cells decreased significantly from day7 to day 21 in culture. Conclusion: cytokines play important role in mTOR expression during hematopoiesis and development of cord blood mononuclear cells.

  10. Chicago Classification of Esophageal Motility Disorders: Lessons Learned

    NARCIS (Netherlands)

    Rohof, W. O. A.; Bredenoord, A. J.

    2017-01-01

    High-resolution manometry (HRM) is increasingly performed worldwide, to study esophageal motility. The Chicago classification is subsequently applied to interpret the manometric findings and facilitate a diagnosis of esophageal motility disorders. This review will discuss new insights regarding the

  11. Chicago transit authority train noise exposure.

    Science.gov (United States)

    Phan, Linh T; Jones, Rachael M

    2017-06-01

    To characterize noise exposure of riders on Chicago Transit Authority (CTA) trains, we measured noise levels twice on each segment of 7 of the 8 CTA train lines, which are named after colors, yielding 48 time-series measurements. We found the Blue Line has the highest noise levels compared to other train lines, with mean 76.9 dBA; and that the maximum noise level, 88.9 dBA occurred in the tunnel between the Chicago and Grand stations. Train segments involving travel through a tunnel had significantly higher noise levels than segments with travel on elevated and ground level tracks. While 8-hr doses inside the passenger cars were not estimated to exceed occupational exposure limits, train operators ride in a separate cab with operational windows and may therefore have higher noise exposures than riders. Despite the low risk of hearing loss for riders on CTA trains, in part because transit noise accounts for a small part of total daily noise exposure, 1-min average noise levels exceeded 85 dBA at times. This confirms anecdotal observations of discomfort due to noise levels, and indicates a need for noise management, particularly in tunnels.

  12. Educators as Activists: Five Women from Chicago.

    Science.gov (United States)

    Munro, Petra

    1995-01-01

    Maintains that during the early 20th century the work of women teacher activists brought issues of social reform to the forefront. Describes the work of five Chicago women who helped advance women's rights, women's suffrage, and other social reform efforts. Contends that their work has not be adequately recognized. (CFR)

  13. Hiding in Plain Sight: Street artists online

    Directory of Open Access Journals (Sweden)

    Kim Barbour

    2013-10-01

    Full Text Available Identity and privacy concerns related to social media are the subject of widespread academic enquiry and mass media reporting. Although in most circumstances academic research tends to present identity play and online self­presentation as positive, media reporting in Australia makes much of the risks of identity theft, privacy breaches and online predators. This research explores the phenomenological experience of creating an online persona, focusing particularly on street artists. For street artists, the threat of unwanted exposure has to be balanced with the positive implications of sharing their creative work outside its geographical and temporal constraints. I argue that street artists use complex persona­creation strategies in order to both protect and promote themselves. The two street artists discussed in this article experience their engagement with social media and digital networks in ways that offer new insight into the opportunities and problems associated with the presentation of a persona online.

  14. ADCP measurements of gravity currents in the Chicago River, Illinois

    Science.gov (United States)

    Garcia, C.M.; Oberg, K.; Garcia, M.H.

    2007-01-01

    A unique set of observations of stratified flow phenomena in the Chicago River was made using an upward-looking acoustic Doppler current profiler (ADCP) during the period November 20, 2003 to February 1, 2004. Water density differences between the Chicago River and its North Branch (NB) seem to be responsible for the development of gravity currents. With the objective of characterizing the occurrence, frequency, and evolution of such currents, the ADCP was configured to continuously collect high-resolution water velocity and echo intensity profiles in the Chicago River at Columbus Drive. During the observation period, 28 gravity current events were identified, lasting a total of 77% of the time. Sixteen of these events were generated by underflows from the NB and 12 of these events were generated by overflows from the NB. On average, the duration of the underflow and overflow events was 52.3 and 42.1 h, respectively. A detailed analysis of one underflow event, which started on January 7, 2004, and lasted about 65h, was performed. This is the first time that ADCP technology has been used to continuously monitor gravity currents in a river. ?? 2007 ASCE.

  15. Evaluation of the Street Pollution Model OSPM for Measurements at 12 Streets Stations Using a Newly Developed and Freely Available Evaluation Tool

    DEFF Research Database (Denmark)

    Ketzel, Matthias; Jensen, Steen Solvang; Brandt, Jørgen

    2012-01-01

    In the present work, the Operational Street Pollution Model (OSPM) has been evaluated in comparison with continuous half-hourly measurements over a multi-year period for five permanent street monitor stations that constitute part of the Danish Air Quality Monitoring Programme as well as with pass......In the present work, the Operational Street Pollution Model (OSPM) has been evaluated in comparison with continuous half-hourly measurements over a multi-year period for five permanent street monitor stations that constitute part of the Danish Air Quality Monitoring Programme as well...... the observations well, especially for the most recent years, while for NO2 the model over-predicts in two cases. The explanation for this over-prediction is believed to be uncertainties in the traffic or emission input data, but also in model parameters, and the representativeness of the urban background data may....... OSPM calculations for nine streets with passive sampler measurements were conducted as ‘blind test’ i.e. without knowing the measured values. OSPM calculations were in good agreement with the measurements for seven out of nine street sections. Refinements of the input data lead to a significant...

  16. Exposure to maltreatment and urban violence in children working on the streets in São Paulo, Brazil: factors associated with street work

    Directory of Open Access Journals (Sweden)

    Andrea F. Mello

    2014-09-01

    Full Text Available Objective: To quantitatively study the exposure to childhood maltreatment and urban violence in children from families with at least one child working on the streets and to investigate the relationship between these factors and street work. Methods: Families who participated in a nongovernmental organization (NGO program to eliminate child labor were included. Data concerning sociodemographic characteristics, punishment methods used in the family environment against the children, five types of abuse and neglect perpetrated by the caregivers, urban violence exposure and family functioning were collected. Results: The sample included 126 children who were working on the streets and 65 siblings who were not working on the streets. Caregivers reported high levels of severe physical punishment. The children reported high levels of abuse and neglect, and high levels of urban violence exposure. The families showed a predominance of dysfunctional and unsatisfactory relationships. A multiple logistic regression model showed that age older than 12 years and severe physical punishment at home were associated with street work. Conclusion: Interventions to decrease the risk of child street work should be family-focused and should aim to reduce violence in the family environment.

  17. Occupy Wall Street

    DEFF Research Database (Denmark)

    Jensen, Michael J.; Bang, Henrik

    2013-01-01

    This article analyzes the political form of Occupy Wall Street on Twitter. Drawing on evidence contained within the profiles of over 50,000 Twitter users, political identities of participants are characterized using natural language processing. The results find evidence of a traditional...

  18. TO THE 70TH ANNIVERSARY OF THE CHICAGO CONVENTION ON INTERNATIONAL CIVIL AVIATION

    Directory of Open Access Journals (Sweden)

    A. V. Neradyiko

    2015-01-01

    Full Text Available The article is devoted to the prerequisite for the development and adoption of the Chicago Convention on International Civil Aviation of 1944. There are given the appreciation of the contents of the convention, it is shown its place and importance in the field of international air law. There is shown the current importance of the Chicago Convention for the development of international civil aviation.

  19. [Who told you to grow old and live on the streets?].

    Science.gov (United States)

    Brêtas, Ana Cristina Passarella; Marcolan, João Fernando; Rosa, Anderson da Silva; Fernandes, Flávia Saraiva Leão; Raizer, Milena Veiga

    2010-06-01

    This qualitative case study is part of another study: Aging, health and work. The objective of this excerpt was to identify the meaning of aging on the streets for the elderly living on the street. The subjects' statements were analyzed under the light of the following themes: history of aging and history of life on the streets. It was understood that the streets are usually a hostile environment for the elderly. It does not guarantee the basic life conditions, affecting the mental health of people who are forced to live on the streets, particularly the elderly. The street does not offer any way out and, together with to the life conditions of the elderly living on the streets leads to the gradual loss of self-esteem, significantly affecting self-care. In addition to these issues, we found that compromised functional capacity puts the life/survival of the elderly living on the streets at risk.

  20. Can activity support influence image of a street?

    Science.gov (United States)

    Tamiami Fachrudin, Hilma

    2018-03-01

    Activity support may affect the formation of the image of a corridor and street. Form, place, and character of activity support in an area will have the function attraction and usefulness of its activities. The aim of this research is to analyze how the influence of activity support on the image of a street, in this case, Dr.Mansyur street which located in front of Universitas Sumatera Utara. Along the street, there are various activities that conducted from morning until evening. The method used is a quantitative method with observation and questionnaire techniques. A population of this study is visitors and students of architecture department from Universitas Sumatera Utara (USU) with sample number is 100 respondents for visitors and 100 respondents for students. Independent variables are activity support factors that consist of the type of activity, form, color, dimension, material, position and lighting. The dependent variable is imageability by [1]. Data were analyzed using logistic regression analysis. The results show that activity support influences image Dr. Mansyur street that has an image as a campus and culinary area and easy to identify.

  1. Characteristics of street children in Cameroon: A cross-sectional study

    Science.gov (United States)

    Cumber, Samuel N.

    2016-01-01

    Introduction The issue of street children is one of the global social problems rising in low- and middle-income countries. These children are vulnerable, but because of a lack of sufficient information, it is very difficult for stakeholders to address their plight in Cameroon. Aim To examine the situation and characteristics of street children in three Cameroonian cities. Objectives To describe the demographic, socio-economic and behavioural profiles of street children. To identify challenges of street children and to compare the results from the three cities on account of their different settings, cultural history and challenges. Materials and methods The study was an analytical cross-sectional survey conducted through researcher-administered questionnaires to 399 street children (homeless for at least a month), in three Cameroonian cities from 1 January 2015 to 30 March 2015. Results The majority of the participants were boys, more than 70% were homeless for less than 12 months and poverty was found to be the most common reason for being on the street. Most of the participants earned less than 500CFA francs (USD 0.85), with many of them resorting to begging, drug abuse, sex work and other risky behaviours. Only two of the respondents (0.5%) regarded the public attitude towards them as supportive. Conclusion As children roam the streets in search of shelter, food and other basic needs, their future hangs in the balance. Understanding the plight of street children highlights the need for immediate design and implementation of intervention strategies to prevent children from living in the streets and assist those who have become street children. PMID:28155316

  2. Aloin Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.

    Science.gov (United States)

    Na, Hee Sam; Song, Yu Ri; Kim, Seyeon; Heo, Jun-Young; Chung, Hae-Young; Chung, Jin

    2016-06-01

    Interleukin (IL)-1β, which is elevated in oral diseases including gingivitis, stimulates epithelial cells to produce IL-8 and perpetuate inflammatory responses. This study investigates stimulatory effects of salivary IL-1β in IL-8 production and determines if aloin inhibits IL-1β-stimulated IL-8 production in epithelial cells. Saliva was collected from volunteers to determine IL-1β and IL-8 levels. Samples from volunteers were divided into two groups: those with low and those with high IL-1β levels. KB cells were stimulated with IL-1β or saliva with or without IL-1 receptor agonist or specific mitogen-activated protein kinase (MAPK) inhibitors. IL-8 production was measured by enzyme-linked immunosorbent assay (ELISA). MAPK protein expression involved in IL-1β-induced IL-8 secretion was detected by Western blot. KB cells were pretreated with aloin, and its effect on IL-1β-induced IL-8 production was examined by ELISA and Western blot analysis. Saliva with high IL-1β strongly stimulated IL-8 production in KB cells, and IL-1 receptor agonist significantly inhibited IL-8 production. Low IL-1β-containing saliva did not increase IL-8 production. IL-1β treatment of KB cells induced activation of MAPK signaling molecules as well as nuclear factor-kappa B. IL-1β-induced IL-8 production was decreased by p38 and extracellular signal-regulated kinase (ERK) inhibitor treatment. Aloin pretreatment inhibited IL-1β-induced IL-8 production in a dose-dependent manner and inhibited activation of the p38 and ERK signaling pathway. Finally, aloin pretreatment also inhibited saliva-induced IL-8 production. Results indicated that IL-1β in saliva stimulates epithelial cells to produce IL-8 and that aloin effectively inhibits salivary IL-1β-induced IL-8 production by mitigating the p38 and ERK pathway. Therefore, aloin may be a good candidate for modulating oral inflammatory diseases.

  3. IL-1 family members IL-18 and IL-33 upregulate the inflammatory potential of differentiated human Th1 and Th2 cultures

    DEFF Research Database (Denmark)

    Blom, Lars; Poulsen, Lars K.

    2012-01-01

    The IL-1 family members IL-1ß, IL-18, and IL-33 are potent cytokines in relationship to amplifying the CD4(+) T cell cytokine production. To evaluate their impact on in vitro-differentiated human Th1 and Th2 cultures, such cultures were established from naive T cells, purified from healthy blood...... donors, and reactivated in the presence of IL-1ß, IL-18, or IL-33. Interestingly, we observe modifying responses in Th1 and Th2 cultures induced by IL-18 or IL-33 but not by IL-1ß, both contributing to amplify production of IL-5, IL-13, and IFN-¿. IL-18 or IL-33 stimulation of Th1 cultures resulted...... in increased IFN-¿ and IL-13 production concurrent with reduced IL-10 gene transcription and secretion even though Th1 cultures, in contrast to IL-18Ra, had low ST2L expression. Furthermore, adding IL-18 to Th1 cultures promoted Tbet mRNA expression and production. Th2 cultures stimulated with IL-18 or IL-33...

  4. Infinite Dimensional Dynamical Systems and their Finite Dimensional Analogues.

    Science.gov (United States)

    1987-01-01

    Rolla ____t___e ___o, __.Paul Steen Cornell Univ.Andrew Szeri Cornell Univ. ByEdriss Titi Univ. of Chicago _Distributi-on/ -S. Tsaltas Unvcrsity of...Cornell University Ithaca, NY 14853 Edriss Titi University of Chicago Dept. of Mathematics 5734 S. University Ave.Chicago, IL 60637 Spiros Tsaltas Dept

  5. Playing With the City: Street Art and Videogames

    OpenAIRE

    Vazques Marquez, Israel; Pajares Tosca, Susana

    2017-01-01

    In this paper we introduce and describe the phenomenon of videogame street art as a specific kind of street art. We consider its materiality and significance, and conceptualize it in the light of a double manifestation of play: the playful appropriation of the city by the artist and the fact that street art encapsulates the act of playing videogames in a visual form. Digital play spills out of our computer screens and occupies the urban space with the explicit intention of involving spectator...

  6. 76 FR 56246 - Self-Regulatory Organizations; Chicago Stock Exchange, Inc.; Notice of Filing and Immediate...

    Science.gov (United States)

    2011-09-12

    ... Organizations; Chicago Stock Exchange, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule..., 2011, the Chicago Stock Exchange, Inc. (``CHX'' or ``Exchange'') filed with the Securities and Exchange... methodology is less subject to manipulation and will allow the Exchange to recoup some of the costs of...

  7. Solar radiation and street temperature as function of street orientation. An analysis of the status quo and simulation of future scenarios towards sustainability in Bahrain

    Science.gov (United States)

    Silva, Joao Pinelo

    2017-11-01

    This paper discusses the contribution of street orientation towards the development of a comfortable microclimate for pedestrians in Bahrain. Increasing walkability is a global agenda to address issues such as a) transportation, b) energy consumption, c) health, and d) air pollution, all of which are topics of the sustainability agenda. Thermal comfort is one of the pre-requisites for walkability. In warm climates, this is a challenging goal. Street design is paramount for pedestrian comfort in warm climates. The roles of street orientation and aspect ratio are of particular importance as they determine the intake of solar radiation into the urban canyon. We investigate the state of affairs in Bahrain, by measuring the frequency with which the street orientations E-W, N-S, NE-SW, and NW-SE, currently occur. Research suggests that the street orientation E-W presents the lesser performance for mitigating the effects of heat gain. The ideal grid orientation would, therefore, be N-S, and NE-SW - NW-SE, avoiding street segments with E-W orientation. A countrywide analysis shows that E-W orientation accounts for the highest overall street length with 37%. The second most frequent orientation is N-S (29%), the best performer. NW-SE and NE-SW both have frequencies of only 17%. Preference for a street grid with N-S, NW-SE, and NE-SW orientation would improve the thermal performance of streets and provide a continuous network of a comfortable pedestrian environment. We simulate two future scenarios based on avoiding new E-W streets, or not. We measure their potential reduction in thermal gain and conclude that a simple policy could reduce solar exposition in 40%.

  8. Parametric laws to model urban pollutant dispersion with a street network approach

    Science.gov (United States)

    Soulhac, L.; Salizzoni, P.; Mejean, P.; Perkins, R. J.

    2013-03-01

    This study discusses the reliability of the street network approach for pollutant dispersion modelling in urban areas. This is essentially based on a box model, with parametric relations that explicitly model the main phenomena that contribute to the street canyon ventilation: the mass exchanges between the street and the atmosphere, the pollutant advection along the street axes and the pollutant transfer at street intersections. In the first part of the paper the focus is on the development of a model for the bulk transfer street/atmosphere, which represents the main ventilation mechanisms for wind direction that are almost perpendicular to the axis of the street. We then discuss the role of the advective transfer along the street axis on its ventilation, depending on the length of the street and the direction of the external wind. Finally we evaluate the performances of a box model integrating parametric exchange laws for these transfer phenomena. To that purpose we compare the prediction of the model to wind tunnel experiments of pollutant dispersion within a street canyon placed in an idealised urban district.

  9. Purification, crystallization and preliminary X-ray diffraction analysis of the IL-20-IL-20R1-IL-20R2 complex

    Energy Technology Data Exchange (ETDEWEB)

    Logsdon, Naomi J.; Allen, Christopher E.; Rajashankar, Kanagalaghatta R.; Walter, Mark R. (Cornell); (UAB)

    2012-02-08

    Interleukin-20 (IL-20) is an IL-10-family cytokine that regulates innate and adaptive immunity in skin and other tissues. In addition to protecting the host from various external pathogens, dysregulated IL-20 signaling has been shown to contribute to the pathogenesis of human psoriasis. IL-20 signals through two cell-surface receptor heterodimers, IL-20R1-IL-20R2 and IL-22R1-IL-20R2. In this report, crystals of the IL-20-IL-20R1-IL-20R2 ternary complex have been grown from polyethylene glycol solutions. The crystals belonged to space group P4{sub 1}2{sub 1}2 or P4{sub 3}2{sub 1}2, with unit-cell parameters a = 111, c = 135 {angstrom}, and diffracted X-rays to 3 {angstrom} resolution. The crystallographic asymmetric unit contains one IL-20-IL-20R1-IL-20R2 complex, corresponding to a solvent content of approximately 54%.

  10. Study on the changes of serum IL-2, IL-6, IL-8 and TNF levels in patients with diabetic nephrosis

    International Nuclear Information System (INIS)

    Qin Wenjing

    2005-01-01

    Objective: To investigate the changes of serum IL-2, IL-6, IL-8 and TNF levels in patients with diabetic nephrosis. Methods: Serum IL-2, IL-6, IL-8 and TNF levels were measured with RIA in 38 patients with diabetic nephrosis and 36 controls. Results: Serum levels of IL-6, IL-8 and TNF were significantly higher in patients with diabetic nephrosis than those in controls (P<0.01), but serum IL-2 levels were significantly lower in the patients (P<0.01). Conclusion: These cytokines participated in the pathogenesis of diabetic nephrosis. Monitoring the changes of their serum levels was helpful for the management of the disease. (authors)

  11. Expression of IL-18, IL-18 Binding Protein, and IL-18 Receptor by Normal and Cancerous Human Ovarian Tissues: Possible Implication of IL-18 in the Pathogenesis of Ovarian Carcinoma

    Directory of Open Access Journals (Sweden)

    Liat Medina

    2014-01-01

    Full Text Available Proinflammatory cytokine IL-18 has been shown to be elevated in the sera of ovarian carcinoma patients. The aim of the study was to examine the levels and cellular origin of IL-18, IL-18 binding protein, and IL-18 receptor in normal and cancerous ovarian tissues. Ovarian tissue samples were examined by immunohistochemical staining for IL-18, IL-18BP, and IL-18R and mRNA of these cytokines was analyzed with semiquantitative PT-PCR. IL-18 levels were significantly higher in cancerous ovarian tissues (P=0.0007, IL-18BP levels were significantly higher in normal ovarian tissues (P=0.04, and the ratio of IL-18/IL-18BP was significantly higher in cancerous ovarian tissues (P=0.036. Cancerous ovarian tissues expressed significantly higher IL-18 mRNA levels (P=0.025, while there was no difference in the expression of IL-18BP mRNA and IL-18R mRNA between cancerous and normal ovarian tissues. IL-18 and IL-18BP were expressed dominantly in the epithelial cells of both cancerous and normal ovarian tissues, while IL-18R was expressed dominantly in the epithelial cells of cancerous ovarian tissues but expressed similarly in the epithelial and stromal cells of normal cancerous tissues. This study indicates a possible role of IL-18, IL-18BP, and IL-18R in the pathogenesis of epithelial ovarian carcinoma.

  12. Reproductive health behaviour of street youth and associated ...

    African Journals Online (AJOL)

    McRoy

    2014-03-30

    Mar 30, 2014 ... street, alcohol drinking, cigarette smoking and khat chewing. Among the .... Street youth: In this study, youth is defined as the people ... factors that influence sexual behaviours of ... means of preventing pregnancy. Condom ...

  13. [Effect of greenbelt on pollutant dispersion in street canyon].

    Science.gov (United States)

    Xu, Wei-Jia; Xing, Hong; Yu, Zhi

    2012-02-01

    The effect feature of greenbelt on flow field and pollutant dispersion in urban street canyon was researched. The greenbelt was assumed as uniform porous media and its aerodynamics property defined by the pressure loss coefficient. Subsequently, the pollutant dispersion in the street canyon of which there was greenbelt in the middle was simulated with the steady-state standard kappa-epsilon turbulence model and species transport equation. The simulated results agreed well with the wind-tunnel data. Compared with the treeless case, it finds that the street canyon contain a clockwise vortex, the pollutant concentration of the leeward was several times than the windward and the growth rate of pollutant concentration was 46.0%. The further simulation for the impact of tree crown position on the airflow and pollutant dispersion finds that the height of major vortex center in the street canyon increases with the height of tree crown and gradually closes the top of windward building This causes that the average wind speed in the street canyon decreases. Especially when the top of tree crown over the roof and hinder the air flow above the street canyon, the average pollutant concentration increases with the height of tree crown rapidly.

  14. History of transportation in Chicago: Its impact on the urban landscape

    Energy Technology Data Exchange (ETDEWEB)

    Plummer, A.V.

    1994-12-31

    In this paper the author presents some of his thoughts on the relationship between transportation and how Chicago used its land. He has chosen to do this by looking at the question from a historical perspective. He attempts to do this by tracking the link between transportation and the use of land. This linkage actually involves only a few simple human factors such as a desire to pay the least amount for land, getting from place to place as swiftly as possible, being paid the most for work done and living in a country-like setting with all of the serenity that image conjures. The author argues these factors are what brought Chicago to where it is, and makes no attempt to judge this as good or bad. The author argues that energy consumption or scarcity, like railroad or transit strikes, have had little long-term effect on how people travel and therefore how they use land. The notion that resources were inexhaustible permeated Chicago`s early history. Human factors appear to the author to have had and probably will continue to have a more profound effect on transportation than anything else. He does not believe society knows what individuals will pay in energy costs to maintain their real or perceived mobility. The real cost of fuel and vehicles is much higher (and so is transit usage) in Europe, but VMT and vehicle ownership still are growing at an astounding rate. Mobility is perceived as good, not bad. How does one convince people to limit their mobility when it is good?

  15. Homicide in Chicago from 1890 to 1930: prohibition and its impact on alcohol- and non-alcohol-related homicides.

    Science.gov (United States)

    Asbridge, Mark; Weerasinghe, Swarna

    2009-03-01

    The aim of the current paper is to examine the impact of the enactment of constitutional prohibition in the United States in 1920 on total homicides, alcohol-related homicides and non-alcohol-related homicides in Chicago. Data are drawn from the Chicago Historical Homicide Project, a data set chronicling 11 018 homicides in Chicago between 1870 and 1930. Interrupted time-series and autoregression integrated moving average (ARIMA) models are employed to examine the impact of prohibition on three separate population-adjusted homicide series. All models control for potential confounding from World War I demobilization and from trend data drawn from Wesley Skogan's Time-Series Data from Chicago. Total and non-alcohol-related homicide rates increased during prohibition by 21% and 11%, respectively, while alcohol-related homicides remained unchanged. For other covariates, alcohol-related homicides were related negatively to the size of the Chicago police force and positively to police expenditures and to the proportion of the Chicago population aged 21 years and younger. Non-alcohol-related homicides were related positively to police expenditures and negatively to the size of the Chicago police force. While total and non-alcohol-related homicides in the United States continued to rise during prohibition, a finding consistent with other studies, the rate of alcohol-related homicides remained unchanged. The divergent impact of prohibition on alcohol- and non-alcohol-related homicides is discussed in relation to previous studies of homicide in this era.

  16. Clinical significance of changes of levels of serum IL-2, IL-8, IL-10 and gastrin in patients with chronic eczema

    International Nuclear Information System (INIS)

    Huang Haifeng; Bi Mingye; Shi Hejian

    2009-01-01

    Objective: To study the significance of changes of serum IL-2, IL-8, IL-10 and Gastrin levels in patients with chronic eczema. Methods: Serum levels of IL-2, IL-8, IL-10 and Gastrin were determined with RIA in 30 patients with chronic eczema and 30 controls. Results: The levels of serum IL-2 were significantly lower in the eczema patients than those in controls (P 0.05). Both serum IL-10 and Gastrin levels were significantly higher in the patients than those in controls (P<0.01). Conclusion: Determination of serum IL-2, IL-8, IL-10 and Gastrin levels in patients with chronic eczema would be of help in monitoring the disease process and outcome prediction. (authors)

  17. Charitable collaborations in Bronzeville, 1928-1944: the "Chicago Defender" and the Regal Theater.

    Science.gov (United States)

    Semmes, Clovis E

    2011-01-01

    In the twentieth century, race-based residential and commercial segregation that supported racial oppression and inequality became an elemental characteristic of urban black communities. Conflict-ridden, black-white relationships were common. However, the Chicago Defender Charities, Inc., the entity that sponsors the largest African American parade in the country and that emerged in 1947, embodied a tradition of charitable giving, self-help, and community service initiated in 1921 by Chicago Defender newspaper founder and editor, Robert S. Abbott. The foundation of this charitable tradition matured as a result of an early and sustained collaboration between Chicago’s white-owned Regal Theater and the black-owned Chicago Defender newspaper. Thus, in segregated African American communities, black and white commercial institutions, under certain conditions, were able to find important points of collaboration to uplift the African American communities of which they were a part.

  18. Notes on LED Installations in Street Illumination

    Directory of Open Access Journals (Sweden)

    Elisabeta Spunei

    2014-09-01

    Full Text Available The paper presents a study made on choosing LED street lighting installations, such that the quality requirements for exterior artificial lighting are fulfilled. We analyze two types of LED street lighting installations from a technical point of view, together with lighting level and brightness values obtained during the measurements. Following on the field measurements, the lighting quality parameters are calculated, and, for the lighting installation with the best performance, optimal mounting suggestions are made. The optimal quality parameters are calculated by simulations using the Dialux software. The same software and the same light sources we also compute an optimal street lighting by determining the size of the installation that provides the best lighting parameter values.

  19. Childcare needs of female street vendors in Mexico City.

    Science.gov (United States)

    Hernandez, P; Zetina, A; Tapia, M; Ortiz, C; Soto, I C

    1996-06-01

    This article reports on strategies developed by female street vendors (vendedoras ambulantes) in Mexico City to ensure the care of their young children in the absence of a specific and operational government policy to fulfil this need. The information concerning child care and health was gathered by a survey of 426 street traders selected by multi-stage random cluster sampling in four of the administrative districts (delegaciones politicas) of Mexico City during 1990. It was found that, as mothers of young children, street vendors most frequently looked after their children personally on the street or left them with other members of the family. Related factors were availability of alternative child care providers in the family, the age of the children and working conditions of the mother. Children who remained on the streets with their mothers suffered more frequently from gastro-intestinal diseases and accidents than the national average. The incidence of acute respiratory diseases, however, was similar in the cases of maternal care in the street and care by family members in another environment. Existing public health measures show a greater concern for the health of food consumers than that of workers in this area. Current public policy seeks to regulate street vending activities and to concentrate traders in ad hoc areas and facilities. Our research results document the need for actions that can contribute to an improvement in the care and health conditions of these young children.

  20. Clinical significance of determination of some serum cytokines (IL-8, IL-10, IL-18, M-CSF) levels in patients with periodontitis

    International Nuclear Information System (INIS)

    Wei Dong; Zhang Xiaolei; Yang Chunxiu; Chen Guanghua

    2008-01-01

    Objective: To explore the significance of changes of serum IL-8, IL-10, IL-18 and M-CSF levels in patients with periodontitis. Methods: Serum levels of IL-8, IL-10, M-CSF (with RIA) and IL-18 (with ELISA) were measured in 55 patients with periodontitis both before and after treatment as well as in 35 controls. Results: Before treatment, serum levels of IL-8, IL-10, IL-18 and M-CSF were significantly higher in the patients than those in the controls (P<0.01). After one month of treatment, the serum IL-8, IL-10, IL-18 and M-CSF levels decreased somewhat, but were still significantly higher than those in controls (P<0.05). Conclusion: There was disturbance of immunomodulation in patients with periodontitis as expressed by the changes of several cytokines levels in the eourse of the diseases. (authors)

  1. Relations Between Serum Essential Fatty Acids, Cytokines (IL-6 & IL ...

    African Journals Online (AJOL)

    The aim of this study was to investigate the relations between free radical generation, interleukins (IL-6 & IL-8), apoptotic marker soluble Fas (sFas), and the level of ... IL-6, IL-8 and sFas whereas serum fatty acid revealed that Linoleicacid (LA) and alpha linolenic acid (ALA) were significantly decreased in the studied cases .

  2. Identification and Characterization of a Novel IL-4 Receptor α Chain (IL-4Rα Antagonist to Inhibit IL-4 Signalling

    Directory of Open Access Journals (Sweden)

    Nayyar Ahmed

    2015-05-01

    Full Text Available Background/Aims: In recent times, allergy has become a financial, physical and psychological burden to the society as a whole. In allergic cascades, cytokine IL-4 binds to IL-4 receptor (IL-4R, consequently producing allergen-specific IgE antibodies by B cells. In addition, among other functions, IL-4 is also responsible for B and T cell proliferation and differentiation. Hence, characterization of novel antagonists that inhibit IL-4 signalling forms the overall aim of this study. Methods: Phage display was used to screen a random 12-mer synthetic peptide library with a human IL-4Rα to identify peptide candidates. Once identified, the peptides were commercially synthesized and used for in vitro immunoassays. Results: We have successfully used phage display to identify M13 phage clones that demonstrated specific binding to IL-4Rα. The peptide N1 was synthesized for use in ELISA, demonstrating significant binding to IL-4Rα and inhibiting interaction with cytokine IL-4. Furthermore, the peptide was tested in a transfected HEK-Blue IL-4 reporter cell line model, which produces alkaline phosphatase (AP. QUANTI-Blue, a substrate, breaks down in the presence of AP producing a blue coloration. Using this colorimetric analysis, >50% inhibition of IL-4 signalling was achieved. Conclusion: We have successfully identified and characterised a synthetic peptide antagonist against IL-4Rα, which effectively inhibits IL-4 interaction with the IL-4Rα in vitro. Since IL-4 interaction with IL-4Rα is a common pathway for many allergies, a prophylactic treatment can be devised by inhibiting this interaction for future treatment of allergies.

  3. 5-Hydroxytryptamine 4 Receptor in the Endothelial Cells

    DEFF Research Database (Denmark)

    Profirovic, Jasmina; Vardya, Irina; Voyno-Yasenetskaya, Tatyana

    2006-01-01

    39 5-HYDROXYTRYPTAMINE 4 RECEPTOR IN THE ENDOTHELIAL CELLS. J. Profirovic, I. Vardya, T. Voyno-Yasenetskaya, Department of Pharmacology, University of Illinois at Chicago, Chicago, IL. Serotonin (5-hydroxytryptamine [5-HT]) is an important neurotransmitter that regulates multiple events in the ce......39 5-HYDROXYTRYPTAMINE 4 RECEPTOR IN THE ENDOTHELIAL CELLS. J. Profirovic, I. Vardya, T. Voyno-Yasenetskaya, Department of Pharmacology, University of Illinois at Chicago, Chicago, IL. Serotonin (5-hydroxytryptamine [5-HT]) is an important neurotransmitter that regulates multiple events...... gap formation in HUVECs. We are currently investigating the mechanism underlying 5-HT4 receptor-induced actin cytoskeleton changes in the endothelial cells. These data suggest that by activating 5-HT4 receptor, serotonin could be involved in regulation of actin cytoskeleton dynamics in the endothelial...

  4. Macrophage Responses to Epithelial Dysfunction Promote Lung Fibrosis in Aging

    Science.gov (United States)

    2017-10-01

    Alexander Misharin CONTRACTING ORGANIZATION: Northwestern University Chicago, IL 60611 REPORT DATE: October 2017 TYPE OF REPORT: Annual PREPARED FOR... University Feinberg School of Medicine Division of Pulmonary and Critical Care 240 E Huron, McGaw M300 Chicago, IL, 60611 9. SPONSORING / MONITORING...weeks, 6, 12, 18 and 24 months), FACSort alveolar macrophages, isolate RNA (Drs. Misharin, Soberanes and Chen). Prepare libraries for RNA-seq

  5. An Art of Resistance: From the Street to the Classroom

    Science.gov (United States)

    Chung, Sheng Kuan

    2009-01-01

    Rooted in graffiti culture and its attitude toward the world, street art is regarded as a postgraffiti movement. Street art encompasses a wide array of media and techniques, such as traditional spray-painted tags, stickers, stencils, posters, photocopies, murals, paper cutouts, mosaics, street installations, performances, and video projections…

  6. 78 FR 20160 - Self-Regulatory Organizations; Chicago Mercantile Exchange Inc.; Notice of Withdrawal of Proposed...

    Science.gov (United States)

    2013-04-03

    ... Organizations; Chicago Mercantile Exchange Inc.; Notice of Withdrawal of Proposed Rule Change Related to the Liquidity Factor of CME's CDS Margin Methodology March 28, 2013. On December 10, 2012, Chicago Mercantile... Section 19(b)(1) of the Securities Exchange Act of 1934 \\1\\ and Rule 19b-4 thereunder,\\2\\ a proposed rule...

  7. Constructing nature as constructing science: expertise, activist science, and public conflict in the Chicago wilderness

    Science.gov (United States)

    Reid M. Helford

    2000-01-01

    In April 1996 an exciting new project was announced, an unprecedented conservation undertaking in one of the nation's most densely populated regions. Chicago Wilderness is a collaborative effort among the more than 90 organizations that make up the Chicago Region Biodiversity Council (CRBC) to protect, restore, and manage the region's natural landscapes...

  8. Brighter future predicted at nuclear meetings in Chicago

    International Nuclear Information System (INIS)

    Stein, H.

    1993-01-01

    This article discusses the future of nuclear power in the United States and the rest of the world. It is a summary of a meeting of the American Nuclear Society/European Nuclear Society in Chicago. Some topics discussed include advanced reactor design, public relations, and nuclear safety

  9. 77 FR 35942 - Procurement List; Proposed Additions

    Science.gov (United States)

    2012-06-15

    ... List for production by the nonprofit agencies listed: Products Hose, Fire, Orange NSN: 4210-01-131-0247.... Contracting Activity: Dept. of Housing and Urban Development, Chicago Regional Office, RCO, Chicago, IL...

  10. 75 FR 70595 - Limited Service Domestic Voyage Load Lines for River Barges on Lake Michigan

    Science.gov (United States)

    2010-11-18

    ... similar request for an eastern Lake Michigan route between Chicago, IL, and Muskegon, MI. The motivation... tow loaded with wheat departed from Milwaukee and traveled southbound for Chicago. Although the 48...

  11. Medline Plus

    Full Text Available ... Cardiac Catheterization: The New Frontier of Coronary Intervention (University of Chicago Medical Center, Chicago, IL, 6/26/2014) Heart Failure Surgical Ventricular Reconstruction (Montefiore Medical Center, New York, ...

  12. Identifying hidden sexual bridging communities in Chicago.

    Science.gov (United States)

    Youm, Yoosik; Mackesy-Amiti, Mary Ellen; Williams, Chyvette T; Ouellet, Lawrence J

    2009-07-01

    Bridge populations can play a central role in the spread of human immunodeficiency virus (HIV) by providing transmission links between higher and lower prevalence populations. While social network methods are well suited to the study of bridge populations, analyses tend to focus on dyads (i.e., risk between drug and/or sex partners) and ignore bridges between distinct subpopulations. This study takes initial steps toward moving the analysis of sexual network linkages beyond individual and risk group levels to a community level in which Chicago's 77 community areas are examined as subpopulations for the purpose of identifying potential bridging communities. Of particular interest are "hidden" bridging communities; that is, areas with above-average levels of sexual ties with other areas but whose below-average AIDS prevalence may hide their potential importance for HIV prevention. Data for this analysis came from the first wave of recruiting at the Chicago Sexual Acquisition and Transmission of HIV Cooperative Agreement Program site. Between August 2005 through October 2006, respondent-driven sampling was used to recruit users of heroin, cocaine, or methamphetamine, men who have sex with men regardless of drug use, the sex partners of these two groups, and sex partners of the sex partners. In this cross-sectional study of the sexual transmission of HIV, participants completed a network-focused computer-assisted self-administered interview, which included questions about the geographic locations of sexual contacts with up to six recent partners. Bridging scores for each area were determined using a matrix representing Chicago's 77 community areas and were assessed using two measures: non-redundant ties and flow betweenness. Bridging measures and acquired immunodeficiency syndrome (AIDS) case prevalence rates were plotted for each community area on charts representing four conditions: below-average bridging and AIDS prevalence, below-average bridging and above

  13. Numerical simulation on pollutant dispersion from vehicle exhaust in street configurations.

    Science.gov (United States)

    Yassin, Mohamed F; Kellnerová, R; Janour, Z

    2009-09-01

    The impact of the street configurations on pollutants dispersion from vehicles exhausts within urban canyons was numerically investigated using a computational fluid dynamics (CFD) model. Three-dimensional flow and dispersion of gaseous pollutants were modeled using standard kappa - epsilon turbulence model, which was numerically solved based on Reynolds-averaged Navier-Stokes equations by the commercial CFD code FLUENT. The concentration fields in the urban canyons were examined in three cases of street configurations: (1) a regular-shaped intersection, (2) a T-shaped intersection and (3) a Skew-shaped crossing intersection. Vehicle emissions were simulated as double line sources along the street. The numerical model was validated against wind tunnel results in order to optimize the turbulence model. Numerical predictions agreed reasonably well with wind tunnel results. The results obtained indicate that the mean horizontal velocity was very small in the center near the lower region of street canyon. The lowest turbulent kinetic energy was found at the separation and reattachment points associated with the corner of the down part of the upwind and downwind buildings in the street canyon. The pollutant concentration at the upwind side in the regular-shaped street intersection was higher than that in the T-shaped and Skew-shaped street intersections. Moreover, the results reveal that the street intersections are important factors to predict the flow patterns and pollutant dispersion in street canyon.

  14. Street Connectivity is Negatively Associated with Physical Activity in Canadian Youth

    Directory of Open Access Journals (Sweden)

    Ian Janssen

    2011-08-01

    Full Text Available Street connectivity, defined as how well streets connect to one and other and the density of intersections, is positively associated with active transportation in adults. Our objective was to study the relation between street connectivity and physical activity in youth. Study participants consisted of 8,535 students in grades 6–10 from 180 schools across Canada who completed the 2006 Health Behaviour in School-aged Children (HBSC survey. Street connectivity was measured in a 5 km circular buffer around these schools using established geographic information system measures. Physical activity performed outside of school hours was assessed by questionnaire, and multi-level regression analyses were used to estimate associations with street connectivity after controlling for several covariates. Compared to students living in the highest street connectivity quartile, those in the second (relative risk = 1.22, 95% confidence interval = 1.10–1.35, third (1.25, 1.13–1.37, and fourth (1.21, 1.09–1.34 quartiles were more likely to be physically active outside of school. In conclusion, youth in neighbourhoods with the most highly connected streets reported less physical activity outside of school than youth from neighbourhoods with less connected streets. Relationships between street connectivity and physical activity reported in this national study are in the opposite direction to those previously observed for active transportation in adult populations.

  15. Analyzing Street Art to Present the Heritage of George Town, Malaysia

    Directory of Open Access Journals (Sweden)

    Seyedehelham Sadatiseyedmahalleh

    2015-08-01

    Full Text Available Street art comprises all kinds of art developed in public locations. This form of art has spread to all heritage streets in George Town, the capital of Penang Island, which is also a known UNESCO World Heritage Site. However, instead of its heritage, food, and interesting past life and structure, the rapid multiplication of street art in George Town has created a new and unusual art that attracts tourists. Street art has spread to small roads and heritage streets in the city. This art increases the awareness of spectators by introducing them to the rich history of these streets and inducing a lively concept in the inner city of George Town. Accordingly, the impact of iron rod sculptures and murals, which comprises approximately 90% of street art in George Town, were determined to explore and identify the effects of this street art on this world heritage site. The findings were obtained from 263 out of 306 questionnaires accomplished by tourists in George Town. The results confirm that tourists prefer murals over iron rod sculptures. Iron rod sculptures are designed to tell the history of the street, whereas murals are designed to create aesthetic value. The findings indicated that similar to iron rod sculptures, more control should be exercised on the subjects of murals.

  16. The City Street

    NARCIS (Netherlands)

    H.C. van der Wouden

    1999-01-01

    Original title: De stad op straat. The city street; the public space in perspective (De stad op straat; de openbare ruimte in perspectief) by the Netherlands Institute for Social Research/SCP is intended to contribute to the formation of new ideas about the public space and the future of

  17. Functional Implications of the IL-23/IL-17 Immune Axis in Schizophrenia.

    Science.gov (United States)

    Debnath, Monojit; Berk, Michael

    2017-12-01

    The aetiology of schizophrenia seems to stem from complex interactions amongst environmental, genetic, metabolic, immunologic and oxidative components. Chronic low-grade inflammation has been persistently linked to schizophrenia, and this has primarily been based on the findings derived from Th1/Th2 cytokine balance. While the IL-23/IL-17 axis plays crucial role in the pathogenesis of several immune-mediated disorders, it has remained relatively unexplored in neuropsychiatric disorders. Altered levels of cytokines related to IL-23/IL-17 axis have been observed in schizophrenia patients in a few studies. In addition, other indirect factors known to confer schizophrenia risk like complement activation and altered gut microbiota are shown to modulate the IL-23/IL-17 axis. These preliminary observations provide crucial clues about the functional implications of IL-23/IL-17 axis in schizophrenia. In this review, an attempt has been made to highlight the biology of IL-23/IL-17 axis and its relevance to schizophrenia risk and pathogenesis. Given the pathogenic potential of the IL-23/IL-17 axis, therapeutic targeting of this axis may be a promising approach to benefit patients suffering from this devastating disorder.

  18. Drug use among street children and adolescents: what helps?

    Directory of Open Access Journals (Sweden)

    Yone Gonçalves de Moura

    Full Text Available The aim of this study was to investigate factors associated to frequent and heavy drug use among street children and adolescents aged 10 to 18 years. A sample of 2,807 street children and adolescents from the 27 Brazilian state capital cities was analyzed. A World Health Organization questionnaire for non-students was adapted for use in Brazil. Data analysis was performed using logistic regression and decision tree models. Factors inversely associated with frequent and heavy drug use were: being age nine to 11 years (OR = 0.1; school attendance (OR = 0.3; daily time (one to five hours spent on the streets (OR = 0.3 and 0.4; not sleeping on the streets (OR = 0.4; being on the streets for less than one year (OR = 0.4; maintenance of some family bonds (OR = 0.5; presence on the streets of a family member (OR = 0.6; not suffering domestic violence (OR = 0.6; being female (OR = 0.8. All of these variables were significant at the p < 0.05 level. The findings suggest that being younger, having family bonds and engagement in school are important protective factors that affect drug use among this population and should be considered in the formulation of public policies.

  19. Rereading the Ethnographic Legacy of the Chicago School of Sociology: Symbolic Interactionism in The Age of Digital Ethnography

    OpenAIRE

    Morva, Oya

    2017-01-01

    The Chicago School of Sociology has made important theoretical and methodological contributions to the field of ethnographic studies. The urban monographs of the early Chicago School and the theory of symbolic interactionism are the most recognised of these contributions. The focus of this study is on the following question: What does the Chicago School’s ethnographic legacy in general and in particular its theory of symbolic interactionism mean for the current digital ethnographic studies? H...

  20. Psoriasis is not associated with IL-12p70/IL-12p40 production and IL12B promoter polymorphism

    DEFF Research Database (Denmark)

    Litjens, Nicolle H R; van der Plas, Mariena J A; Ravensbergen, Bep

    2004-01-01

    Psoriasis is a type-1 T cell-mediated, chronic inflammatory disease. Since interleukin (IL)-12p70 promotes the development of type-1 T cells, we investigated whether psoriasis is associated with an increased production of this cyctokine by blood cells. Results revealed that the production of IL-12p....... The frequencies of the various genotypes for the promoter region of the gene encoding IL-12p40 (IL12B) did not differ between psoriasis patients and controls. No association was observed between the various IL12B promoter genotypes and the LPS-stimulated production of IL-12p70 or IL-12p40 by blood cells. Together......, psoriasis is not associated with a promoter polymorphism in the IL12B gene nor with the production of IL-12p70 by LPS-stimulated blood cells....

  1. Identification on the street: A field comparison of police street identifications and video line-ups in England

    OpenAIRE

    Davis, Josh P.; Valentine, Tim; Memon, Amina; Roberts, Andrew J.

    2015-01-01

    A street identification or live show-up provides an eyewitness with an opportunity to identify a suspect shortly after a crime. In England, the majority of suspects identified are subsequently included in a video line-up for the same witness to view. In Study 1, robbery squad data from three English police forces recorded 696 crimes, the identification procedures employed and prosecution decisions. A street identification was the most frequent identification procedure, being attempted in 22.7...

  2. The Code of the Street and Violent Versus Property Crime Victimization.

    Science.gov (United States)

    McNeeley, Susan; Wilcox, Pamela

    2015-01-01

    Previous research has shown that individuals who adopt values in line with the code of the street are more likely to experience violent victimization (e.g., Stewart, Schreck, & Simons, 2006). This study extends this literature by examining the relationship between the street code and multiple types of violent and property victimization. This research investigates the relationship between street code-related values and 4 types of victimization (assault, breaking and entering, theft, and vandalism) using Poisson-based multilevel regression models. Belief in the street code was associated with higher risk of experiencing assault, breaking and entering, and vandalism, whereas theft victimization was not related to the street code. The results suggest that the code of the street influences victimization broadly--beyond violence--by increasing behavior that provokes retaliation from others in various forms.

  3. Street children in Mafikeng, North-West Province: A qualitative study ...

    African Journals Online (AJOL)

    The general perception, on the part of South African society, is that street children are a major social menace. Yet the reality is that, street children are a vulnerable group that suffer both psychological and physical violence including sexual abuse. This qualitative study investigated the social experiences of street children in ...

  4. Socio-economic and hygiene features of street food vending in ...

    African Journals Online (AJOL)

    The objectives of the study were firstly to determine the health risks associated with street food vending, secondly to determine the opinions of street food ... such as South Africa be allowed to earn their livelihood by means of an 'easy-to-enter' business such as street food vending when hygiene standards are acceptable.

  5. 76 FR 20371 - Notice of Lodging of Consent Decree Under the Comprehensive Environmental Response, Compensation...

    Science.gov (United States)

    2011-04-12

    ... decree, GM obtained a performance bond from Westchester Fire Insurance Company (``Westchester''). After... Dearborn St., Chicago, Illinois 60604, and at U.S. EPA Region 5, 77 W. Jackson Blvd., Chicago, IL 60604...

  6. Lead in Glasgow street dirt and soil

    Energy Technology Data Exchange (ETDEWEB)

    Farmer, J G [Univ. of Glasgow; Lyon, T D.B.

    1977-07-01

    The levels of lead in city street dirt and in soil from various locations in Glasgow were investigated during spring 1976. Lead concentrations in street dirt ranged from 150 to 2300 ppM, mean 960 ppM, and were significantly elevated with respect to the observed ''natural'' level of 78 ppM. Lead derived from anti-knock compounds in petrol and introduced to the environment via automobile exhausts was clearly implicated as the main source of lead pollution in a series of soil lead measurements at the centre and periphery of eight Glasgow parks. Various chemical leaching techniques were employed and compared. Less than 5 percent of street dirt and soil lead was found to be associated with the organic phase.

  7. Street-Level Bureaucrats as Individual Policymakers:

    DEFF Research Database (Denmark)

    Baviskar, Siddhartha; Winter, Søren

    2016-01-01

    Lipsky (1980) pointed out that street-level bureaucrats (SLBs) are important policymakers due to the discretion they exercise and argued from a structural perspective that these workers manifest relatively similar coping behaviors owing to their shared working conditions, characterized by chronic......Lipsky (1980) pointed out that street-level bureaucrats (SLBs) are important policymakers due to the discretion they exercise and argued from a structural perspective that these workers manifest relatively similar coping behaviors owing to their shared working conditions, characterized...

  8. Fasting induces IL-1 resistance and free fatty acid-mediated up-regulation of IL-1R2 and IL-1RA

    Directory of Open Access Journals (Sweden)

    jenifer j joesting

    2014-07-01

    Full Text Available Objective: Weight loss is a near societal obsession and many diet programs use significant calorie restriction (CR including fasting/short term starvation to generate rapid effects. Fasting is also a well-recognized cause of immunosuppression especially within the innate immune system. In this study, we sought to determine if the IL-1 arm of the neuroimmune system was down-regulated by a 24 hr fast and how fasting might generate this effect. Design: Mice were allowed ad libitum access to food or had food withheld for 24 hrs. Expression of the endogenous IL-1 antagonists IL-1 receptor type 2 (IL-1R2 and IL-1 receptor antagonist (IL-1RA were determined as were sickness behaviors before and after IL-1 administration.Results: Fasting markedly increased gene expression of IL-1R2 (83-fold in adipose tissue, 9.5-fold in liver and IL-1RA (68-fold in liver. Fasted mice were protected from IL-1-induced weight loss, hypoglycemia, loss of locomotor and social anxiety. These protections were coupled to a large positive interaction of fasting and IL-1 on IL-1R2 gene expression in adipose tissue and liver (2.6-fold and 1.6-fold, respectively. Fasting not only increased IL-1RA and IL-1R2 protein 2.5-fold and 3.2-fold, respectively, in liver; but also increased IL-1R2 1.8-fold in adipose tissue. Fasting, in turn, triggered a 2.4-fold increase in plasma free-fatty acids (FFAs and a 2.1-fold increase in plasma corticosterone. Inhibition, of glucocorticoid action with mifepristone did not impact fasting-dependent IL-1R2 or IL-1RA gene expression. Administration of the FFA, palmitate, to mice increased liver IL-1R2 and IL-1RA gene expression by 14-fold and 11-fold, respectively. Conclusion: These findings indicate that fasting augments expression of endogenous IL-1 antagonists inducing IL-1 resistance. Fasting-induced increases in plasma FFAs appears to be a signal that drives immunosuppression during fasting/short term starvation.

  9. Clinical significance of measurement of changes of serum IL-6, IL-18 and IL-1β levels after treatment in patients with endometriosis

    International Nuclear Information System (INIS)

    Zhang Chunyan; Zhang Shumin; Zhou Dongxia; Wang Enbo

    2008-01-01

    Objective: To explore the clinical significance of changes of serum IL-6, IL-18 and IL-1β levels after treatment in patients with endometriosis. Methods: Serum IL-6 (with RIA) and IL-18, IL-1β (with ELISA) levels were determined in 38 patients with endometriosis both before and after treatment as well as 35 controls. Results: Before treatment, the serum IL-6, IL- 18 and IL-1β levels were significantly higher in the patients than those in controls (P 0.05). Conclusion: Detection of serum IL-6, IL-18 and IL- 1β levels might reflect the progress of diseases in patients with endometriosis. (authors)

  10. CODASC : a database for the validation of street canyon dispersion models

    OpenAIRE

    Gromke, C.B.

    2013-01-01

    CODASC stands for Concentration Data of Street Canyons (CODASC 2008, www.codasc.de). It is a database which provides traffic pollutant concentrations in urban street canyons obtained from wind-tunnel dispersion experiments. CODASC comprises concentration data of street canyons with different aspect ratios subjected to various wind directions and also for street canyons with tree-avenues. The database includes concentration data of tree-avenue configurations of different tree arrangement, tree...

  11. Playing With the City: Street Art and Videogames

    DEFF Research Database (Denmark)

    Vazques Marquez, Israel; Pajares Tosca, Susana

    2017-01-01

    In this paper we introduce and describe the phenomenon of videogame street art as a specific kind of street art. We consider its materiality and significance, and conceptualize it in the light of a double manifestation of play: the playful appropriation of the city by the artist and the fact...... that street art encapsulates the act of playing videogames in a visual form. Digital play spills out of our computer screens and occupies the urban space with the explicit intention of involving spectators, who are invited to play in symbolic ways that actualize nostalgic memories of gaming and can be related...

  12. The Origin of the ‘Chicago Method’ Excavation Techniques: Contributions of William Nickerson and Frederick Starr

    Directory of Open Access Journals (Sweden)

    David Browman

    2013-09-01

    Full Text Available What were the origins of the ‘Chicago method’ of scientific excavation? What is it and how did it get that name? Does its origin predate its popular employment at excavations in the USA during the 1930s and 1940s, and go back to institutional competition between Frederic Ward Putnam of the Field Museum and Frederick Starr of the University of Chicago? Or was it the result of the fieldwork of avocational archaeologist and one of Putnam’s first students, William Baker Nickerson, who implemented it as the basis of his fieldwork, and proved its efficacy, for many years before he retired in 1921? Nickerson’s detailed notes on the results of his thorough stratigraphic excavation techniques, used at many archaeological sites in Iowa, Illinois, Ohio and Minnesota, were passed on to the first University of Chicago field party doing archaeological work in Illinois, that consequently became the foundations of the later ‘Chicago method’.

  13. Seasonal influenza A/H3N2 virus infection and IL-1Β, IL-10, IL-17, and IL-28 polymorphisms in Iranian population.

    Science.gov (United States)

    Rogo, Lawal Dahiru; Rezaei, Farhad; Marashi, Seyed Mahdi; Yekaninejad, Mir Saeed; Naseri, Maryam; Ghavami, Nastaran; Mokhtari-Azad, Talat

    2016-12-01

    Increased blood cytokines is the main immunopathological process that were attributed to severe clinical outcomes in cases of influenza A/H3N2 virus infection. The study was aimed to investigate the polymorphisms of IL-1β, IL-10, IL-17, and IL-28 genes to find the possibility of their association with the clinical outcome of influenza A/H3N2 virus infection among the infected patients in Iran. This is a Case-Control study in which influenza A/H3N2 virus positive confirmed with real-time PCR were the cases. DNA samples from groups were genotyped for polymorphisms in rs16944 (IL-1β), rs1800872 (IL-10), rs2275913 (IL-17), and rs8099917 (IL-28). Confidence interval (95%CI) and Odds ratio (OR) were calculated. IL-17 rs2275913 (GG and AG) were associated with risk of infection with that were statistically significant (P rs16944) (GG) was associated with reduced risk of infection (P < 0.01, OR = 0.46). Genotype GG and GT of IL-10 (rs1800872) were associated with increased risk of infection with influenza A/H3N2 virus (P < 0.05, OR = 2.04-2.58). In addition, IL-28 (rs8099917) genotypes GG (P < 0.05, OR = 0.49) and TG (P < 0.05, OR = 0.59) were associated with reduced risk of ILI symptom while genotype TT (P < 0.01, OR = 4.31) was associated with increased risk of ILI symptom. The results of this study demonstrated that polymorphisms of genes involved in the inflammatory and anti-inflammatory process affect the outcome of disease caused by influenza A/H3N2 virus. Thorough insight on host immune response at the time of influenza A virus infection is required to ensure adequate patient care in the case of feature outbreaks. J. Med. Virol. 88:2078-2084, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  14. A qualitative enquiry into OpenStreetMap making

    Science.gov (United States)

    Lin, Yu-Wei

    2011-04-01

    Based on a case study on the OpenStreetMap community, this paper provides a contextual and embodied understanding of the user-led, user-participatory and user-generated produsage phenomenon. It employs Grounded Theory, Social Worlds Theory, and qualitative methods to illuminate and explores the produsage processes of OpenStreetMap making, and how knowledge artefacts such as maps can be collectively and collaboratively produced by a community of people, who are situated in different places around the world but engaged with the same repertoire of mapping practices. The empirical data illustrate that OpenStreetMap itself acts as a boundary object that enables actors from different social worlds to co-produce the Map through interacting with each other and negotiating the meanings of mapping, the mapping data and the Map itself. The discourses also show that unlike traditional maps that black-box cartographic knowledge and offer a single dominant perspective of cities or places, OpenStreetMap is an embodied epistemic object that embraces different world views. The paper also explores how contributors build their identities as an OpenStreetMaper alongside some other identities they have. Understanding the identity-building process helps to understand mapping as an embodied activity with emotional, cognitive and social repertoires.

  15. Pregnancy, but not the allergic status, influences spontaneous and induced interleukin-1beta (IL-1beta), IL-6, IL-10 and IL-12 responses.

    Science.gov (United States)

    Amoudruz, Petra; Minang, Jacob Taku; Sundström, Yvonne; Nilsson, Caroline; Lilja, Gunnar; Troye-Blomberg, Marita; Sverremark-Ekström, Eva

    2006-09-01

    In this study, we investigated how pregnancy influences cytokine production in response to stimulation of the innate and the adaptive immune system, respectively. Peripheral blood mononuclear cells (PBMCs) from allergic (n = 44) and non-allergic (n = 36) women were collected at three time-points: during the third trimester, at delivery and at a non-pregnant state 2 years after delivery. The production of interleukin-1beta (IL-1beta), IL-6, IL-10 and IL-12 was measured by enzyme-linked immunosorbent assay (ELISA) or enzyme-linked immunospot assay (ELISPOT). The spontaneous cytokine production, and the response following stimulation with agents that primarily activate the adaptive part of the immune system [phytohaemagglutinin (PHA), allergen extracts from cat and birch], or lipopolysaccharide (LPS) that activate innate immunity was measured in vitro. There was a significantly higher spontaneous in vitro production of IL-1beta, IL-6 and IL-10 by PBMCs during pregnancy than 2 years after pregnancy, and this was not affected by the allergic status of the women. Conversely, in PHA-stimulated cell cultures there was a lower production of IL-10 and IL-12 during pregnancy than 2 years after pregnancy. LPS-induced IL-6 levels were significantly lower in PBMCs obtained during pregnancy than at 2 years after pregnancy. In addition, we made the interesting observation that in allergic women total immunoglobulin E (IgE) levels were significantly lower 2 years after pregnancy compared to the levels during pregnancy. Taken together, our results indicate that while atopic allergy in women does not have a substantial effect on cytokine production, pregnancy has an obvious effect on the immune system in terms of cytokine production as well as on the total IgE levels.

  16. Formerly Utilized MED/AEC Sites Remedial Action Program. Project management plan for the decontamination of Jones Laboratory, Ryerson Physical Laboratory, and Eckhart Hall, the University of Chicago, Chicago, Illinois

    International Nuclear Information System (INIS)

    Flynn, K.F.; Smith, W.H.; Wynveen, R.A.

    1984-01-01

    The Department of Energy (DOE) has in place a plan for the decontamination and decommissioning of contaminated sites that had been formerly utilized by the Manhattan Engineering District (MED) and/or the Atomic Energy Commission. This plan is referred to as the Formerly Utilized Sites Remedial Action Program (FUSRAP). Among these sites are Jones Laboratory, Ryerson Physical Laboratory and Eckhart Hall of The University of Chicago at Chicago, Illinois. This document represents the Project Management Plan for the decontamination of these facilities. 13 references, 3 figures, 1 table

  17. Formerly Utilized MED/AEC Sites Remedial Action Program. Project management plan for the decontamination of Jones Laboratory, Ryerson Physical Laboratory, and Eckhart Hall, the University of Chicago, Chicago, Illinois

    Energy Technology Data Exchange (ETDEWEB)

    Flynn, K.F.; Smith, W.H.; Wynveen, R.A.

    1984-01-01

    The Department of Energy (DOE) has in place a plan for the decontamination and decommissioning of contaminated sites that had been formerly utilized by the Manhattan Engineering District (MED) and/or the Atomic Energy Commission. This plan is referred to as the Formerly Utilized Sites Remedial Action Program (FUSRAP). Among these sites are Jones Laboratory, Ryerson Physical Laboratory and Eckhart Hall of The University of Chicago at Chicago, Illinois. This document represents the Project Management Plan for the decontamination of these facilities. 13 references, 3 figures, 1 table.

  18. Structure of IL-22 Bound to Its High-Affinity IL-22R1 Chain

    Energy Technology Data Exchange (ETDEWEB)

    Jones, B.C.; Logsdon, N.J.; Walter, M.R. (UAB)

    2008-09-29

    IL-22 is an IL-10 family cytokine that initiates innate immune responses against bacterial pathogens and contributes to immune disease. IL-22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2 receptor chains and further regulated by interactions with a soluble binding protein, IL-22BP, which shares sequence similarity with an extracellular region of IL-22R1 (sIL-22R1). IL-22R1 also pairs with the IL-20R2 chain to induce IL-20 and IL-24 signaling. To define the molecular basis of these diverse interactions, we have determined the structure of the IL-22/sIL-22R1 complex. The structure, combined with homology modeling and surface plasmon resonance studies, defines the molecular basis for the distinct affinities and specificities of IL-22 and IL-10 receptor chains that regulate cellular targeting and signal transduction to elicit effective immune responses.

  19. Street art a jeho vliv na současnou českou malbu

    OpenAIRE

    Grabmüllerová, Eva

    2009-01-01

    Street Art and Its Influence on Contemporary Czech Painting Street art as a concept refers to an artistic expression, which is, however, not defined by one homogenous technique or subject. The only attribute that conjoins the diverse forms and subjects of street art is a very specific urban area utilization. Although street art encompasses many diverse forms and techniques, the most prevalent ones are sticker art, street posters art, stencil graffiti, murals, traditional graffiti artwork, art...

  20. Social Sustainability of Shopping Streets in Ankara

    Directory of Open Access Journals (Sweden)

    Özge YALÇINER ERCOŞKUN

    2013-02-01

    Full Text Available Shopping streets are integral parts of public spaces in traditional shopping areas of Central Business Districts (CBD. Furthermore, as modern shopping venues, shopping centers offer advantages for modern lifestyles with spacious shopping areas, variety of commercial and social activities, and economic value of their investments. These advantages act in favor of shopping centers and improve the level of shopping street social sustainability and its relevant concepts. The aim of this study is to analyze the main shopping streets of Ankara, using the concepts of social sustainability. In this study, these concepts, such as locality, identity, vitality, viability, sense of place, conviviality, meaning and local characteristics of the shopping streets are investigated. For the first time, the retail unit locations in Ankara, their brands and their business types, are illustrated on thematic land use maps using Geographical Information Systems (GIS software. Next, population activities and consumer spatial behavior are observed and marked on maps that are also referred to as social sustainability maps. The results of the study can be useful in formulating strategies within the framework of social sustainability, which is a relatively new concept.

  1. A street rubbish detection algorithm based on Sift and RCNN

    Science.gov (United States)

    Yu, XiPeng; Chen, Zhong; Zhang, Shuo; Zhang, Ting

    2018-02-01

    This paper presents a street rubbish detection algorithm based on image registration with Sift feature and RCNN. Firstly, obtain the rubbish region proposal on the real-time street image and set up the CNN convolution neural network trained by the rubbish samples set consists of rubbish and non-rubbish images; Secondly, for every clean street image, obtain the Sift feature and do image registration with the real-time street image to obtain the differential image, the differential image filters a lot of background information, obtain the rubbish region proposal rect where the rubbish may appear on the differential image by the selective search algorithm. Then, the CNN model is used to detect the image pixel data in each of the region proposal on the real-time street image. According to the output vector of the CNN, it is judged whether the rubbish is in the region proposal or not. If it is rubbish, the region proposal on the real-time street image is marked. This algorithm avoids the large number of false detection caused by the detection on the whole image because the CNN is used to identify the image only in the region proposal on the real-time street image that may appear rubbish. Different from the traditional object detection algorithm based on the region proposal, the region proposal is obtained on the differential image not whole real-time street image, and the number of the invalid region proposal is greatly reduced. The algorithm has the high mean average precision (mAP).

  2. Beats on the Table: Beat Writing in the Chicago Review and Big Table

    Directory of Open Access Journals (Sweden)

    Jaap van der Bent

    2012-07-01

    Full Text Available Normal 0 21 false false false NL X-NONE X-NONE MicrosoftInternetExplorer4 Kleine literaire tijdschriften, zogenaamde little magazines, hebben een belangrijke rol gespeeld bij de doorbraak, in de loop van de jaren vijftig, van de Amerikaanse Beat Generation. Aangezien grotere uitgeverijen en de gevestigde tijdschriften lange tijd terugschrokken voor de zowel inhoudelijk als formeel van de norm afwijkende uitingen van de Beats, verscheen hun werk aanvankelijk vooral in kleinere tijdschriften als de twee waaraan in dit artikel aandacht wordt besteed: de Chicago Review en Big Table. Aan de hand van een beschrijving van de inhoud van deze twee tijdschriften wordt geprobeerd duidelijk te maken hoe het werk van de Beat Generation zich in deze tijdschriften gaandeweg een eigen plaats verwierf. Speciale aandacht wordt besteed aan de rol van de redacteuren Irving Rosenthal en Paul Carroll; door zijn uitgekiende strategie om voor het omstreden werk van Beat-auteur William S. Burroughs geleidelijk een steeds grotere plaats in te ruimen, bepaalde vooral Rosenthal het veranderende karakter van de Chicago Review. De veranderingen bij dat tijdschrift verliepen niet zonder slag of stoot en waren voor de eigenaar ervan, de University of Chicago, op een gegeven moment aanleiding om de Chicago Review aan censuur te onderwerpen. Ook deze censuur en de reactie erop, de oprichting van Big Table, worden in het artikel belicht.

  3. 77 FR 71680 - Buckeye East Chicago Railroad, LLC-Acquisition and Operation Exemption-Buckeye Partners, L.P.

    Science.gov (United States)

    2012-12-03

    ... Chicago Railroad, LLC--Acquisition and Operation Exemption--Buckeye Partners, L.P. Buckeye East Chicago... acquire from Buckeye Partners, L.P., a noncarrier, and to operate approximately 7,065 feet (1.34 miles) of..., 2012. By the Board, Rachel D. Campbell, Director, Office of Proceedings. Jeffrey Herzig, Clearance Unit...

  4. A Challenge to Change: Necessary Changes in the Library Classification System for the Chicago Public Schools.

    Science.gov (United States)

    Williams, Florence M.

    This report addresses the feasibility of changing the classification of library materials in the Chicago Public School libraries from the Dewey Decimal classification system (DDC) to the Library of Congress system (LC), thus patterning the city school libraries after the Chicago Public Library and strengthening the existing close relationship…

  5. Three-Dimensional Conformal Radiotherapy in Prostate Cancer Patients: Rise in Interleukin 6 (IL-6) but not IL-2, IL-4, IL-5, Tumor Necrosis Factor-{alpha}, MIP-1-{alpha}, and LIF Levels

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira Lopes, Carlos [Universidade do Vale do Paraiba, Centro de Oncologia Radioterapica do Vale do Paraiba, Universidade do Vale do Paraiba Instituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraiba, Sao Jose dos Campos, Sao Paulo (Brazil); Callera, Fernando, E-mail: fcallera@gmail.com [Centro de Hematologia Onco-hematologia e Transplantes de Medula Ossea do Vale do Paraiba, Sao Paulo (Brazil)

    2012-03-15

    Purpose: To investigate the effect of radiotherapy (RT) on serum levels of interleukin-2 (IL-2), IL-4, IL-5, IL-6, tumor necrosis factor alpha (TNF-{alpha}), macrophage inflammatory protein-1-alpha (MIP-1-{alpha}) and leukemia inhibitory factor (LIF) in patients with prostate cancer. Methods and Materials: Forty eight patients with prostate cancer received three-dimensional conformal blocking radiation therapy with a linear accelerator. IL-2, IL-4, IL-5, IL-6, TNF-{alpha}, MIP-1-{alpha}, and LIF levels were measured by the related immunoassay kit 1 day before the beginning of RT and during RT at days 15 and 30. Results: The mean IL-2 values were elevated before and during the RT in contrast with those of IL-4, IL-5, IL-6, TNF-{alpha}, MIP-1-{alpha}, and LIF, which were within the normal range under the same conditions. Regarding markers IL-2, IL-4, IL-5, TNF-{alpha}, MIP-1-{alpha}, and LIF, comparisons among the three groups (before treatment and 15 and 30 days during RT) did not show significant differences. Although values were within the normal range, there was a significant rise in IL-6 levels at day 15 of RT (p = 0.0049) and a decline at day 30 to levels that were similar to those observed before RT. Conclusions: IL-6 appeared to peak after 15 days of RT before returning to pre-RT levels. In contrast, IL-2, IL-4, IL-5, TNF-{alpha}, MIP-1-{alpha}, and LIF levels were not sensitive to irradiation. The increased levels of IL-6 following RT without the concurrent elevation of other cytokines involved in the acute phase reaction did not suggest a classical inflammatory response to radiation exposure. Further studies should be designed to elucidate the role of IL-6 levels in patients with prostate cancer treated with RT.

  6. Neighborhood sampling: how many streets must an auditor walk?

    Science.gov (United States)

    McMillan, Tracy E; Cubbin, Catherine; Parmenter, Barbara; Medina, Ashley V; Lee, Rebecca E

    2010-03-12

    This study tested the representativeness of four street segment sampling protocols using the Pedestrian Environment Data Scan (PEDS) in eleven neighborhoods surrounding public housing developments in Houston, TX. The following four street segment sampling protocols were used (1) all segments, both residential and arterial, contained within the 400 meter radius buffer from the center point of the housing development (the core) were compared with all segments contained between the 400 meter radius buffer and the 800 meter radius buffer (the ring); all residential segments in the core were compared with (2) 75% (3) 50% and (4) 25% samples of randomly selected residential street segments in the core. Analyses were conducted on five key variables: sidewalk presence; ratings of attractiveness and safety for walking; connectivity; and number of traffic lanes. Some differences were found when comparing all street segments, both residential and arterial, in the core to the ring. Findings suggested that sampling 25% of residential street segments within the 400 m radius of a residence sufficiently represents the pedestrian built environment. Conclusions support more cost effective environmental data collection for physical activity research.

  7. Saving Mango Street

    Science.gov (United States)

    Van Winkle, Katie

    2012-01-01

    The author first learned about cultural diversity and racial justice in Mr. Sanderson's middle school English class. They read a book called "The House on Mango Street" by Sandra Cisneros and learned about a different culture, but also about a community with striking similarities to their own. The main character in the novel, Esperanza,…

  8. Restoring Detroit's Street Lighting System

    Energy Technology Data Exchange (ETDEWEB)

    Kinzey, Bruce [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-09-30

    The City of Detroit is in the midst of a comprehensive restoration of its street lighting system that includes transitioning the existing HPS sources to LED. This report provides an objective review of the circumstances surrounding the system restoration, the processes undertaken and decisions made, and the results so far — and contains useful information about issues that arise during large-scale LED street lighting projects.

  9. IL-4 function can be transferred to the IL-2 receptor by tyrosine containing sequences found in the IL-4 receptor alpha chain.

    Science.gov (United States)

    Wang, H Y; Paul, W E; Keegan, A D

    1996-02-01

    IL-4 binds to a cell surface receptor complex that consists of the IL-4 binding protein (IL-4R alpha) and the gamma chain of the IL-2 receptor complex (gamma c). The receptors for IL-4 and IL-2 have several features in common; both use the gamma c as a receptor component, and both activate the Janus kinases JAK-1 and JAK-3. In spite of these similarities, IL-4 evokes specific responses, including the tyrosine phosphorylation of 4PS/IRS-2 and the induction of CD23. To determine whether sequences within the cytoplasmic domain of the IL-4R alpha specify these IL-4-specific responses, we transplanted the insulin IL-4 receptor motif (I4R motif) of the huIL-4R alpha to the cytoplasmic domain of a truncated IL-2R beta. In addition, we transplanted a region that contains peptide sequences shown to block Stat6 binding to DNA. We analyzed the ability of cells expressing these IL-2R-IL-4R chimeric constructs to respond to IL-2. We found that IL-4 function could be transplanted to the IL-2 receptor by these regions and that proliferative and differentiative functions can be induced by different receptor sequences.

  10. 77 FR 47671 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-08-09

    ... Chicago, IL February 26, 2012. Marketing, Chicago Division, Schawk, Creative Circle, Aquent, etc.. 81,790... section 222 has not been met. TA-W No. Subject firm Location Impact date 81,538 State Journal Springfield...

  11. Narcolepsy/Cataplexy and Occult Neuroblastoma

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2013-11-01

    Full Text Available Investigators at the University of Chicago and Northwestern University, Chicago, IL; University Hospital Southampton, UK; and Kiev Paediatric Hospital, Ukraine, report three children with narcolepsy and cataplexy subsequently diagnosed with neuroblastoma.

  12. Increased IL-10 mRNA and IL-23 mRNA expression in multiple sclerosis: interferon-beta treatment increases IL-10 mRNA expression while reducing IL-23 mRNA expression

    DEFF Research Database (Denmark)

    Krakauer, M.; Sorensen, P.; Khademi, M.

    2008-01-01

    volunteers served to confirm initial findings. mRNA was analyzed by real-time reverse transcriptase polymerase chain reaction (PCR). RESULTS: We found elevated expression of interleukin (IL)-23 and IL-10 in untreated MS patients. IFN-beta therapy increased IL-10 and decreased IL-23 expression independently...... of the regulatory cytokine IL-10. The elevated IL-23 mRNA levels in MS patients are noteworthy in view of the newly discovered IL-23-driven Th17 T-cell subset, which is crucial in animal models of MS. Since IFN-beta therapy resulted in decreased IL-23 mRNA levels, the Th17 axis could be another target of IFN...

  13. Theoretical high energy physics research at the University of Chicago

    International Nuclear Information System (INIS)

    Rosner, J.L.; Martinec, E.J.; Sachs, R.G.

    1990-09-01

    This report discusses research being done at the University of Chicago in High Energy Physics. Some topic covered are: CP violation; intermediate vector bosons; string models; supersymmetry; and rare decay of kaons

  14. CODASC : a database for the validation of street canyon dispersion models

    NARCIS (Netherlands)

    Gromke, C.B.

    2013-01-01

    CODASC stands for Concentration Data of Street Canyons (CODASC 2008, www.codasc.de). It is a database which provides traffic pollutant concentrations in urban street canyons obtained from wind-tunnel dispersion experiments. CODASC comprises concentration data of street canyons with different aspect

  15. 75 FR 12590 - Self-Regulatory Organizations; The Chicago Stock Exchange, Inc.; Order Approving a Proposed Rule...

    Science.gov (United States)

    2010-03-16

    ... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-61680; File No. SR-CHX-2009-18] Self-Regulatory Organizations; The Chicago Stock Exchange, Inc.; Order Approving a Proposed Rule Change To Amend Its Co-Location Fees March 10, 2010. I. Introduction On December 22, 2009, the Chicago Stock Exchange, Inc. (``CHX'' or...

  16. IL6 and IL10 are genetic susceptibility factors of periodontal disease

    Directory of Open Access Journals (Sweden)

    Luca Scapoli

    2012-01-01

    Conclusions: The present investigation indicated that polymorphisms of IL6 and IL10 constitute risk factors for chronic periodontitis, while there was no evidence implicating a specific IL1A or IL1B genotype.

  17. The lived experiences of children living on the streets of Hillbrow

    Directory of Open Access Journals (Sweden)

    Chris Myburgh

    2015-05-01

    Full Text Available Background: The effects of daily abuse and hardship on the streets lead to poor mental health in children living on the streets, resulting in them choosing ineffective and self-destructive coping strategies that impact their physical health and overall sense of wellbeing. The facilitation of the mental health of children living on the streets who are subjected to daily threats to their survival is thus crucial. Objectives: The aim of this research was to explore and describe the lived experiences of children living on the streets of Hillbrow, Johannesburg. Method: The research design was qualitative, exploratory, descriptive and contextual. A purposive sample was selected through a temporary shelter in Johannesburg, Gauteng, South Africa and consisted of 14 male children living on the streets. Data were collected using drawings, in-depth phenomenological interviews and field notes. The central interview opening statement was: ‘Tell me about your life on the street’. Results: The results obtained indicated that children living on the streets are threatened, exploited and exposed to physical, sexual and emotional abuse on a daily basis by the community, the authorities and other street dwellers. This leads to feelings of sadness, fear, anxiety, misery, despair, hopelessness, helplessness and suicide ideation, which in turn lead to drug abuse and criminal activities. In contrast, positive feelings of sympathy for other children living on the streets emerged and these children also displayed perseverance, resilience and a striving for autonomy. Conclusion: Street life exposes children to a variety of experiences, both positive and negative. A striving after autonomy is clearly depicted by these children, who are able to tap into a range of responses, both on- and off-street.

  18. Density and diversity of OpenStreetMap road networks in China

    Directory of Open Access Journals (Sweden)

    Yingjia Zhang

    2015-12-01

    Full Text Available OpenStreetMap is a geographic information platform designed to provide real-time updates and user-generated content related to its freely available global map, and it is one of the most widely used examples of volunteered geographic information, a technique associated with so-called neogeography. This paper, based on the data from China’s OpenStreetMap road network in May 2014, taking 340 prefecture-level cities in China as its study area, presents the geometric-related (road density and attribute-related (type diversity spatial patterns of the OpenStreetMap road network, and explores their relationship. The results are as follows. (1 The distribution of OpenStreetMap road density in Shenzhen, Shanghai, Hong Kong, and Macao predominantly obeys a “positive skewness distribution”. OpenStreetMap data for eastern China shows a higher overall and circular structure. In central China, there are noticeable discrepancies in the road density, whereas in western China, the road density is low. (2 The OpenStreetMap road diversity shows a normal distribution. The spatial pattern for the so-called “Hu Huanyong line” was broken by the effect of diplomatic and strategic factors, showing a high diversity along the peripheral border, coastal cities, and core inland cites. (3 China’s OpenStreetMap is partitioned into four parts according to road density and diversity: high density and high diversity; low density and low diversity; high density and low diversity; and low density high diversity. (4 The OpenStreetMap geographical information-collection process and mechanism were analyzed, demonstrating that the road density reflects the preponderance of traffic in the real world. OpenStreetMap road diversity reflects the road-related geographic information demand and value, and it also reflects the interests of users toward to OpenStreetMap geographical information.

  19. IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis.

    LENUS (Irish Health Repository)

    Reeves, Emer P

    2010-02-01

    Dysregulation of airway inflammation contributes to lung disease in cystic fibrosis (CF). Inflammation is mediated by inflammatory cytokines, including IL-8, which illustrates an increase in biological half-life and proinflammatory activity when bound to glycosaminoglycans (GAGs). The aim of this project was to compare IL-8 and IL-18 for their relative stability, activity, and interaction with GAGs, including chondroitin sulfate, hyaluronic acid, and heparan sulfate, present in high quantities in the lungs of patients with CF. Bronchoalveolar lavage fluid was collected from patients with CF (n = 28), non-CF controls (n = 14), and patients with chronic obstructive pulmonary disease (n = 12). Increased levels of IL-8 and reduced concentrations of IL-18 were detected in bronchial samples obtained from CF individuals. The low level of IL-18 was not a defect in IL-18 production, as the pro- and mature forms of the molecule were expressed and produced by CF epithelial cells and monocytes. There was, however, a marked competition between IL-8 and IL-18 for binding to GAGs. A pronounced loss of IL-18 binding capacity occurred in the presence of IL-8, which displaced IL-18 from these anionic-matrices, rendering the cytokine susceptible to proteolytic degradation by neutrophil elastase. As a biological consequence of IL-18 degradation, reduced levels of IL-2 were secreted by Jurkat T lymphocytes. In conclusion, a novel mechanism has been identified highlighting the potential of IL-8 to determine the fate of other inflammatory molecules, such as IL-18, within the inflammatory milieu of the CF lung.

  20. Study on the changes of serum TNF-α, IL-1β, IL-6 and IL-8 levels in patients with coronary cardiac heart diseases

    International Nuclear Information System (INIS)

    Lu Xiaozhuo; Yu Xian

    2003-01-01

    Objective: To study the role TNF-α, IL-1β, IL-6 and IL-8 played in the pathogenesis of coronary cardiac heart diseases. Methods: Serum levels of TNF-α, IL-1β, IL-6 and IL-8 levels were determined by chemiluminescence immunoassay in 32 patients with stable angina, 39 patients with acute myocardial infarction and 36 controls. Results: Serum TNF-α, IL-1β, IL-6 and IL-8 levels in all patients were higher than those in controls. Remarkably increased level were seen in acute myocardial infarction group. Difference between control and patient groups were: stable angina group TNF-α, p<0.05, IL-6, p<0.01 and IL-8, p<0.05; acute myocardial infarction group TNF-α, p<0.01, IL-1β, p<0.05, IL-6, p<0.001 and IL-8, p<0.001. Conclusion: There is close relationship between serum TNF-α, IL-1β, IL-6, IL-8 levels and development of coronary cardiac heart disease. They play an important role in the pathogenesis through mutual induction and synergistic actions

  1. A man of his time: thorstein veblen and the university of chicago darwinists.

    Science.gov (United States)

    Raymer, Emilie J

    2013-01-01

    The Darwinian economic theory that Thorstein Veblen proposed and refined while he served as a professor of Political Economy at the University of Chicago from 1891 to 1906 should be assessed in the context of the community of Darwinian scientists and social scientists with whom Veblen worked and lived at Chicago. It is important to identify Veblen as a member of this broad community of Darwinian-inclined philosophers, physiologists, geologists, astronomers, and biologists at Chicago because Veblen's involvement with this circle suggests that the possible sources of his engagement with Darwinism extend beyond the pragmatists and Continental socialists to whom scholars have typically ascribed Veblen's Darwinian roots. Additionally, that an extensive community continued to use Darwinian evolutionary theory to construct new models of scientific and social scientific analysis at the turn of the twentieth century, a period during which Darwinism was purportedly in decline, suggests that the "eclipse of Darwinism" narrative has been overstated in literature about Darwinism's intellectual arc.

  2. The secreted form of the p40 subunit of interleukin (IL)-12 inhibits IL-23 functions and abrogates IL-23-mediated antitumour effects

    Science.gov (United States)

    Shimozato, Osamu; Ugai, Shin-ichi; Chiyo, Masako; Takenobu, Hisanori; Nagakawa, Hiroyasu; Wada, Akihiko; Kawamura, Kiyoko; Yamamoto, Hiroshi; Tagawa, Masatoshi

    2006-01-01

    Interleukin (IL)-23 is a heterodimeric cytokine consisting of a novel p19 molecule and the p40 subunit of IL-12. Since secreted p40 can act as an antagonist for IL-12, we investigated whether p40 also inhibited IL-23-mediated immunological functions. p40 did not induce interferon (IFN)-γ or IL-17 production from splenocytes but impaired IL-23-induced cytokine production by competitive binding to the IL-23 receptors. Furthermore, a mixed population of murine colon carcinoma Colon 26 cells transduced with the p40 gene and those transduced with the IL-23 gene developed tumours in syngenic mice, whereas the IL-23-expressing Colon 26 cells were completely rejected. p40 also suppressed IFN-γ production of antigen-stimulated splenocytes and IL-23-mediated cytotoxic T-lymphocyte activities in the mice that rejected Colon 26 cells expressing IL-23. p40 can thereby antagonize IL-23 and is a possible therapeutic agent for suppression of IL-23 functions. PMID:16423037

  3. IL22/IL-22R pathway induces cell survival in human glioblastoma cells.

    Directory of Open Access Journals (Sweden)

    Hussein Akil

    Full Text Available Interleukin-22 (IL-22 is a member of the IL-10 cytokine family that binds to a heterodimeric receptor consisting of IL-22 receptor 1 (IL-22R1 and IL-10R2. IL-22R expression was initially characterized on epithelial cells, and plays an essential role in a number of inflammatory diseases. Recently, a functional receptor was detected on cancer cells such as hepatocarcinoma and lung carcinoma, but its presence was not reported in glioblastoma (GBM. Two GBM cell lines and 10 primary cell lines established from patients undergoing surgery for malignant GBM were used to investigate the expression of IL-22 and IL-22R by using quantitative RT-PCR, western blotting and confocal microscopy studies. The role of IL-22 in proliferation and survival of GBM cell lines was investigated in vitro by BrdU and ELISA cell death assays. We report herein that the two subunits of the IL-22R complex are expressed on human GBM cells. Their activation, depending on exogenous IL-22, induced antiapoptotic effect and cell proliferation. IL-22 treatment of GBM cells resulted in increased levels of phosphorylated Akt, STAT3 signaling protein and its downstream antiapoptotic protein Bcl-xL and decreased level of phosphorylated ERK1/2. In addition, IL-22R subunits were expressed in all the 10 tested primary cell lines established from GBM tumors. Our results showed that IL-22R is expressed on GBM established and primary cell lines. Depending on STAT3, ERK1/2 and PI3K/Akt pathways, IL-22 induced GBM cell survival. These data are consistent with a potential role of IL-22R in tumorigenesis of GBM. Since endogenous IL-22 was not detected in all studied GBM cells, we hypothesize that IL-22R could be activated by immune microenvironmental IL-22 producing cells.

  4. Trees as environmental modifier to improve street canyon for pedestrian activities in Muscat

    Science.gov (United States)

    Khudhayer, Wael A.; Shaaban, Awni K.; Sukor, Nur Sabahiah Abdul

    2017-10-01

    Street shading efficiency is a function of orientation and profile proportion of its height to width. Under high sun altitude conditions, minimization of solar irradiance within the urban environment may often be a significant criterion in urban design. This reduction in solar irradiance achieved when the obstruction angle is large (high H/W ratio, H=height, W=width). High H/W values often lessen the solar access to streets. The horizontal sprawl of Muscat region is an example of low H/W ratio represented the remarkable challenge that causes the lack of shading rates in the urban street. This characteristic proliferates the negative impact on the pedestrian activities in the urban street. This research aims to improve the morphology of the street to promote the pedestrian behavior. The amendment based on suggesting different configurations of trees to increase effective shading of the urban street in Muscat. The street canyon abstracted into a virtual elongated channel formed of floor and walls of equal heights on both sides. Four street orientations (E/W, N/S, NE/SW, NW/SE) and three H/W ratio (0.5,1 and 2) are considered sufficient representative of street typologies. A mathematical model developed for calculation of shading efficiency of each street canyon. The trees assumed in this study as canyon's modifier to adjust the low H/W ratio of a street canyon to a higher one. Local trees and other plants in Muscat were studied concerning their morphology. The analysis selected two case study in Muscat to investigate the shading performance of their street canyons subsequently propose the modifications to improve it. The research concluded that the suggested changes of the street canyon by using a particular type of trees could increase the H/W ratio of street canyon significantly.

  5. CURB-BASED STREET FLOOR EXTRACTION FROM MOBILE TERRESTRIAL LIDAR POINT CLOUD

    Directory of Open Access Journals (Sweden)

    S. Ibrahim

    2012-07-01

    Full Text Available Mobile terrestrial laser scanners (MTLS produce huge 3D point clouds describing the terrestrial surface, from which objects like different street furniture can be generated. Extraction and modelling of the street curb and the street floor from MTLS point clouds is important for many applications such as right-of-way asset inventory, road maintenance and city planning. The proposed pipeline for the curb and street floor extraction consists of a sequence of five steps: organizing the 3D point cloud and nearest neighbour search; 3D density-based segmentation to segment the ground; morphological analysis to refine out the ground segment; derivative of Gaussian filtering to detect the curb; solving the travelling salesman problem to form a closed polygon of the curb and point-inpolygon test to extract the street floor. Two mobile laser scanning datasets of different scenes are tested with the proposed pipeline. The results of the extracted curb and street floor are evaluated based on a truth data. The obtained detection rates for the extracted street floor for the datasets are 95% and 96.53%. This study presents a novel approach to the detection and extraction of the road curb and the street floor from unorganized 3D point clouds captured by MTLS. It utilizes only the 3D coordinates of the point cloud.

  6. IL-28 and IL-29 as protective markers in subject with dengue fever.

    Science.gov (United States)

    Hung, Chih-Hsing; Huang, Chung-Hao; Wang, Lin; Huang, Chun-Chi; Wu, Meng-Chieh; Chin, Yi-Ying; Lin, Chun-Yu; Chang, Ko; Wu, Deng-Chyang; Chen, Yen-Hsu

    2017-06-01

    About 400 million people every year are estimated to contract dengue virus infection, which causes prolonged morbidity and sometimes mortality. Interleukin (IL)-28 and IL-29 are relatively newly discovered cytokines and play an important role in our immune defense against pathogens, especially for viral infection. In the present study, we investigated serum IL-28 and IL-29 expression and the relationship to clinical and laboratory parameters in patients with dengue virus infection. Adult patients with dengue (n = 45) and control group (n = 24) were included prospectively. Clinical symptoms and laboratory data were collected from every patient. We investigated IL-28 and IL-29 levels in serum by ELISA. The concentrations of serum IL-28 and IL-29 were significantly higher in subjects with dengue when compared to those of control group. The patients with higher serum IL-28 and IL-29 levels had significantly lower ALAT and peripheral blood neutrophil percentage, but higher peripheral platelet, total white blood cell (WBC), monocyte, and lymphocyte counts. Patients with higher serum IL-28 and IL-29 levels also had more flu-like symptoms, but less vomiting. Increased level of IL-28 and IL-29 was associated with better liver function, platelet and WBC numbers and clinical symptom in subjects with dengue and could potentially serve as a protective marker.

  7. Il-legitimacy in the eyes of the il-legitimated

    DEFF Research Database (Denmark)

    Gerstroem, Anna

    2013-01-01

    The financial crisis has brought il-legitimacy to the center of organizational life in the banking industry. It is unfortunate that little is known about how organizational il-legitimacy is experienced and handled by the people who spend most of their wakening hours at work within...... these organizations. The purpose of this paper is to address this gap of knowledge by exploring how members of a bankrupted bank experience and handle attributions of organizational il-legitimacy: to investigate the phenomenon from an inside perspective - in the eyes of the people who undergo it. The paper has...... an inductive approach and offers an explorative analysis based on an in-depth study of qualitative interviews with 20 members of a bankrupted bank. The analysis shows that in bankers’ narrations, (il)legitimacy is central: as a problem and as a solution. The paper contributes to extant knowledge on (il...

  8. Street Cries and the urban refrain

    DEFF Research Database (Denmark)

    Kreutzfeldt, Jacob

    2012-01-01

    Rasmussen have investigated Danish street cries as respectably a musical and a spatial phenomenon. Such studies – from each their perspectives – can be said to explore the aesthetics of urban environments, since street calls are specifically developed and heard in the context of the city. Investigating...... the different methods employed in the two studies and presenting Deleuze and Guattaris theory about the refrain as a framework for further studies in the field, this article seeks to outline a fertile area of study for sound studies: the investigation of everyday refrains and the environmental relations...

  9. Recombinant human growth-regulated oncogene-alpha induces T lymphocyte chemotaxis. A process regulated via IL-8 receptors by IFN-gamma, TNF-alpha, IL-4, IL-10, and IL-13

    DEFF Research Database (Denmark)

    Jinquan, T; Frydenberg, Jane; Mukaida, N

    1995-01-01

    receptors on the cells. This process can be augmented by IFN-gamma and TNF-alpha, and inhibited by IL-4, IL-10, and IL-13. In addition, we also document that on T lymphocytes there exist IL-8 receptors that can be up-regulated by IFN-gamma, TNF-alpha, and IL-2. Our results demonstrate that rhGRO-alpha gene...

  10. Interleukin (IL)-8 and IL-36γ but not IL-36Ra are related to acrosyringia in pustule formation associated with palmoplantar pustulosis.

    Science.gov (United States)

    Xiaoling, Y; Chao, W; Wenming, W; Feng, L; Hongzhong, J

    2018-06-12

    Palmoplantar pustulosis (PPP) is a refractory, nonbacterial impetigo confined to the palms and soles. Its pathogenesis is still obscure, but it may be associated with the large eccrine sweat glands and pores of palmoplantar skin. PPP is considered to be a localized pustular psoriasis. Interleukin (IL)-8, IL-36γ and IL-36Ra play important roles in the pathogenesis of pustular psoriasis, but their role in PPP is unclear. To evaluate IL-8, IL-36γ and IL-36Ra expression in PPP, and their relationship with acrosyringia and pustule formation. mRNA expression was quantified in skin samples from patients with PPP (n = 7), patients with psoriasis vulgaris (PSV; n = 8) and healthy controls (HCs) (n = 6) by reverse-transcription-real-time PCR. Protein expression was characterized by immunohistochemistry (PPP, n = 17; PSV, n = 14; HCs, n = 12). Sweat ducts, including acrosyringia, were stained for epithelial membrane antigen (EMA). IL-8 mRNA and protein were markedly increased in PPP lesions compared with PSV lesions or HC skin. IL-36γ mRNA and protein were significantly more abundant in PPP lesions than in HC skin. IL-36Ra mRNA was significantly overexpressed in PPP lesions compared with HC skin, but there was no difference in IL-36Ra protein between PPP, PSV and HCs. IL-8 was abundantly expressed by neutrophils in PPP pustules, while IL36Ra was localized in the keratinocytes of PPP, PSV and HC skin. IL-36γ and EMA were colocalized in cells surrounding PPP pustules, and IL-36γ was also expressed in sweat duct cells in the dermis. IL-8, IL-36γ and IL-36Ra are overexpressed in PPP lesions. IL-8, IL-36γ and acrosyringia, rather than IL-36Ra, are associated with pustule formation in PPP. © 2018 British Association of Dermatologists.

  11. Trees in the city: valuing street trees in Portland, Oregon

    Science.gov (United States)

    G.H. Donovan; D.T. Butry

    2010-01-01

    We use a hedonic price model to simultaneously estimate the effects of street trees on the sales price and the time-on-market (TOM) of houses in Portland. Oregon. On average, street trees add $8,870 to sales price and reduce TOM by 1.7 days. In addition, we found that the benefits of street trees spill over to neighboring houses. Because the provision and maintenance...

  12. Genome-wide association study of genetic variants in LPS-stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α cytokine response in a Danish Cohort

    DEFF Research Database (Denmark)

    Larsen, Margit Hørup; Albrechtsen, Anders; Thørner, Lise Wegner

    2013-01-01

    Cytokine response plays a vital role in various human lipopolysaccharide (LPS) infectious and inflammatory diseases. This study aimed to find genetic variants that might affect the levels of LPS-induced interleukin (IL)-6, IL-8, IL-10, IL-1ra and tumor necrosis factor (TNF)-α cytokine production....

  13. Relationships as determinants of substance use amongst street ...

    African Journals Online (AJOL)

    Background: Unrestrained exposure to street life often makes the street child vulnerable to psychoactive substances. In other settings, the social relationships of the substance user with those around him or her and family norms of parenting have been docu-mented to modulate use. However, there is a dearth of literature on ...

  14. Teaching Pharmaceutical Biotechnology at the University of Illinois at Chicago.

    Science.gov (United States)

    Groves, Michael J.; Klegerman, Melvin E.

    1988-01-01

    The Department of Pharmaceutics at the University of Illinois at Chicago has been carrying out research in pharmaceutical biotechnology that has allowed unique student involvement and promises further interdisciplinary research and instructional activities. (MSE)

  15. The Influence of Vegetation Function towards the Langsep Street Thermal Comfort

    Science.gov (United States)

    Alfian, R.; Setyabudi, I.; Uran, R. S.

    2017-10-01

    Streetscape is an important element for character building of the environment, spatial, and visual in order to provide an urban identity, especially in Malang City protocol streets. Langsep Street is one of the protocol streets in Malang City. Langsep Street famous with central education and offices area. This study aims (1) to identify vegetation of streetscape; (2) to analyze the thermal comfort of the streetscape, and (3) to evaluate the comfort level of Langsep Street. The method used was the THI approach. THI value that obtained was analyzed using the standard of Laurie (1990). Based on observations, the THI value of Langsep Street was 27.60. This was influenced by the trees canopy density and spacing of the trees on the streetscape. It can be concluded that streetscape required (1) shaded plants that have root systems that do not damage the construction of roads, (2) the branching plants are not easily broken and easy to maintain, and (3) the combination of trees, shrubs and ground cover.

  16. The Ballet of the Streets: Teaching about Cities at Street Level

    Science.gov (United States)

    McGuire, Patrick A.; Spates, James L.

    2011-01-01

    The urban scholar Jane Jacobs once described city life as "the ballet of the streets." In more than a quarter century of joint teaching, the authors have used Jacobs' metaphor to help their students understand that cities are living organisms created and maintained, for good or ill, by the people who live and work in them. At heart their…

  17. Solar radiation and street temperature as function of street orientation. An analysis of the status quo and simulation of future scenarios towards sustainability in Bahrain

    Directory of Open Access Journals (Sweden)

    Silva Joao Pinelo

    2017-01-01

    A countrywide analysis shows that E-W orientation accounts for the highest overall street length with 37%. The second most frequent orientation is N-S (29%, the best performer. NW-SE and NE-SW both have frequencies of only 17%. Preference for a street grid with N-S, NW-SE, and NE-SW orientation would improve the thermal performance of streets and provide a continuous network of a comfortable pedestrian environment. We simulate two future scenarios based on avoiding new E-W streets, or not. We measure their potential reduction in thermal gain and conclude that a simple policy could reduce solar exposition in 40%.

  18. Renaming Zagreb Streets and Squares

    Directory of Open Access Journals (Sweden)

    Jelena Stanić

    2009-06-01

    Full Text Available The paper deals with changes in street names in the city of Zagreb. Taking the Lower Town (Donji grad city area as an example, the first part of the paper analyses diachronic street name changes commencing from the systematic naming of streets in 1878. Analysis of official changes in street names throughout Zagreb’s history resulted in categorisation of five periods of ideologically motivated naming/name-changing: 1. the Croatia modernisation period, when the first official naming was put into effect, with a marked tendency towards politicisation and nationalisation of the urban landscape; 2. the period of the Kingdom of the Serbs, Croatians and Slovenians/Yugoslavia, when symbols of the new monarchy, the idea of the fellowship of the Southern Slavs, Slavenophilism and the pro-Slavic geopolitical orientation were incorporated into the street names, and when the national idea was highly evident and remained so in that process; 3. the period of the NDH, the Independent State of Croatia, with decanonisation of the tokens of the Yugoslavian monarchy and the Southern Slavic orientation, and reference to the Ustashi and the German Nazi and Italian Fascist movement; 4. the period of Socialism, embedding the ideals and heroes of the workers’ movement and the War of National Liberation into the canonical system; and, 5. the period following the democratic changes in 1990, when almost all the signs of Socialism and the Communist/Antifascist struggle were erased, with the prominent presence of a process of installing new references to early national culture and historical tradition. The closing part of the paper deals with public discussions connected with the selection of a location for a square to bear the name of the first president of independent Croatia, Franjo Tuđman. Analysis of these public polemics shows two opposing discourses: the right-wing political option, which supports a central position for the square and considers the chosen area to

  19. Tobacco Taxation, Smuggling, and Street Tobacco Vendors in Eritrea

    International Development Research Centre (IDRC) Digital Library (Canada)

    The bulk of the smuggled cigarettes are sold by street vendors, many of them women and children, ... and its implications for government revenue;; identify the reasons why people sell on the streets; and, ... Agent(e) responsable du CRDI.

  20. Il danno alla persona del lavoratore: il mobbing orizzontale

    Directory of Open Access Journals (Sweden)

    Riccardo Gentile

    2011-12-01

    Full Text Available Sommario:1. Il mobbing tra diritto civile e diritto del lavoro – 2. Il fenomeno mobbing: gli studi iniziali e la definizione – 3. Le concrete condotte integranti fattispecie di mobbing – 4. Onere della prova – 5. Il mobbing orizzontale – 6. L’elemento soggettivo di colpevolezza del da­tore di lavoro nella responsabilità ex art. 2087 c.c. per mobbing orizzontale

  1. Identification of Avian and Hemoparasite DNA in Blood-Engorged Abdomens of Culex pipiens (Diptera; Culicidae) from a West Nile Virus Epidemic region in Suburban Chicago, Illinois.

    Science.gov (United States)

    Boothe, Emily; Medeiros, Matthew C I; Kitron, Uriel D; Brawn, Jeffrey D; Ruiz, Marilyn O; Goldberg, Tony L; Walker, Edward D; Hamer, Gabriel L

    2015-05-01

    Multiple mosquito-borne parasites cocirculate in nature and potentially interact. To understand the community of parasites cocirculating with West Nile virus (WNV), we screened the bloodmeal content of Culex pipiens L. mosquitoes for three common types of hemoparasites. Blood-fed Cx. pipiens were collected from a WNV-epidemic area in suburban Chicago, IL, from May to September 2005 through 2010. DNA was extracted from dissected abdomens and subject to PCR and direct sequencing to identify the vertebrate host. RNA was extracted from the head or thorax and screened for WNV using quantitative reverse transcriptase PCR. Seventy-nine engorged females with avian host origin were screened using PCR and amplicon sequencing for filarioid nematodes, Haemosporida, and trypanosomatids. Filarioid nematodes were identified in 3.8% of the blooded abdomens, Plasmodium sp. in 8.9%, Haemoproteus in 31.6%, and Trypanosoma sp. in 6.3%. The sequences from these hemoparasite lineages were highly similar to sequences from birds in prior studies in suburban Chicago. Overall, 50.6% of blood-fed Culex pipiens contained hemoparasite DNA in their abdomen, presumably from current or prior bloodmeals. Additionally, we detected hemoparasite DNA in the blooded abdomen of three of 10 Cx. pipiens infected with WNV. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. Exploring the World using Street View 360 Images

    Science.gov (United States)

    Bailey, J.

    2016-12-01

    The phrase "A Picture is Worth a Thousand Words" is an idiom of unknown 20th century origin. There is some belief that the modern use of the phrase stems from an article in a 1921 issue of a popular trade journal, that used "One Look is Worth A Thousand Words" to promote the use of images in advertisements on the sides of streetcars. There is a certain irony to this as nearly a century later the camera technologies on "Street View cars" are collecting images that look everywhere at once. However, while it can be to fun drive along the World's streets, it was the development of Street View imaging systems that could be mounted on other modes of transport or capture platforms (Street View Special Collects) that opened the door for these 360 images to become a tool for exploration and storytelling. Using Special Collect imagery captured in "off-road" and extreme locations, scientists are now using Street View images to assess changes to species habitats, show the impact of natural disasters and even perform "armchair" geology. A powerful example is the imagery captured before and after the 2011 earthquake and tsunami that devastated Japan. However, it is use of the immersive nature of 360 images that truly allows them to create wonder and awe, especially when combined with Virtual Reality (VR) viewers. Combined with the Street View App or Google Expeditions, VR provides insight into what it is like to swim with sealions in the Galapagos or climb El Capitan in Yosemite National Park. While these image could never replace experiencing these locations in real-life, they can inspire the viewer to explore and learn more about the many wonders of our planet. https://www.google.com/streetview/https://www.google.com/expeditions/

  3. 76 FR 11944 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2011-03-04

    ......... 1/3821 2/7/11 RNAV (GPS) RWY 19, Orig 7-Apr-11 SC Columbia Jim Hamilton L.B. 1/4017 2/8/11 GPS RWY.../11 RNAV (GPS) RWY 3, Orig 7-Apr-11 IL Chicago Chicago-O'Hare Intl. 0/7506 2/7/11 ILS OR LOC RWY 9L..... 0/8316 2/7/11 RNAV (GPS) RWY 15, Orig 7-Apr-11 NE Nebraska City....... Nebraska City Muni.. 0/8318 2...

  4. Associations of vascular endothelial growth factor (VEGF gene and cytokine (IL-1B, IL-4, IL-6, IL-10, TNFA genes combinations with type 2 diabetes mellitus in women

    Directory of Open Access Journals (Sweden)

    Vladimir Iosifovich Konenkov

    2012-09-01

    Full Text Available Aim. To study the association between vascular endothelial growth factor (VEGF and cytokine (IL1B, IL4, IL6, IL10 and TNFAgene polymorphism combinations with type 2 diabetes mellitus (T2DM in women. Materials and methods. 374 Caucasian women without carbohydrate metabolism disorders from 23 to 68 years of age and 212 womenwith T2DM from 28 to 69 years of age were included in the study. The combinations of polymorphism А-2578С, С+936Т in VEGFgene with polymorphism in IL1B С-31Т, IL4 С-590Т, IL6 G-174C, IL10 A-592C and А-1082G, TNFA А-238G, A-308G and A-863Cwere studied. Results. Analysis revealed 52 combined genetic variations with different rate of occurrence between diabetic and control groups(р

  5. Wind-induced single-sided natural ventilation in buildings near a long street canyon: CFD evaluation of street configuration and envelope design

    DEFF Research Database (Denmark)

    Ai, Z.T.; Mak, C.M.

    2018-01-01

    an urban context, this study investigates the wind-induced single-sided natural ventilation in buildings near a long street canyon under a perpendicular wind direction using CFD method. Four aspect ratios (AR) of the street canyon, from 1.0, 2.0, 4.0 to 6.0, are investigated to examine the influence...

  6. MAINTENANCE OF THE CARPARK AND STREET LIGHTING

    CERN Multimedia

    ST-FM Group

    2002-01-01

    The ST Division informs you that the control and maintenance of the carpark and street lighting will be carried out during the next few weeks. These lightings work normally by photocells but during these tests they will be turned on zone by zone during the day. So we ask the users not to be surprised to see the street lighting on during the day and thank them for their comprehension. ST-FM Group

  7. Designing safe and inclusive streets in India | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-11-17

    Nov 17, 2016 ... In fast-growing Indian cities such as Ahmedabad, streets are also the site of conflict. ... while instances of violence against women are partly linked to land ... by poor street design, and to develop people-centred alternatives.

  8. Influence of local parameters on the dispersion of traffic-related pollutants within street canyons

    Science.gov (United States)

    Karra, Styliani; Malki-Epshtein, Liora; Martin Hyde Collaboration

    2011-11-01

    Ventilation within urban cities and street canyons and the associated air quality is a problem of increasing interest in the last decades. It is important for to minimise exposure of the population to traffic-related pollutants at street level. The residence time of pollutants within the street canyons depends on the meteorological conditions such as wind speed and direction, geometry layout and local parameters (position of traffic lane within the street). An experimental study was carried out to investigate the influence of traffic lane position on the dispersion of traffic-related pollutants within different street canyons geometries: symmetrical (equal building heights on both sides of the street), non-symmetrical (uniform building heights but lower on one side of the street) and heterogeneous (non-uniform building heights on both sides of the street) under constant meteorological conditions. Laboratory experiments were carried out within a water channel and simultaneous measurements of velocity field and concentration scalar levels within and above the street canyons using PIV and PLIF techniques. Traffic -related emissions were simulated using a line emission source. Two positions were examined for all street geometries: line emission source was placed in the centre of the street canyon; line emission source was placed off the centre of the street. TSI Incorporated.

  9. Street trees reduce the negative effects of urbanization on birds.

    Science.gov (United States)

    Pena, João Carlos de Castro; Martello, Felipe; Ribeiro, Milton Cezar; Armitage, Richard A; Young, Robert J; Rodrigues, Marcos

    2017-01-01

    The effects of streets on biodiversity is an important aspect of urban ecology, but it has been neglected worldwide. Several vegetation attributes (e.g. street tree density and diversity) have important effects on biodiversity and ecological processes. In this study, we evaluated the influences of urban vegetation-represented by characteristics of street trees (canopy size, proportion of native tree species and tree species richness)-and characteristics of the landscape (distance to parks and vegetation quantity), and human impacts (human population size and exposure to noise) on taxonomic data and functional diversity indices of the bird community inhabiting streets. The study area was the southern region of Belo Horizonte (Minas Gerais, Brazil), a largely urbanized city in the understudied Neotropical region. Bird data were collected on 60 point count locations distributed across the streets of the landscape. We used a series of competing GLM models (using Akaike's information criterion for small sample sizes) to assess the relative contribution of the different sets of variables to explain the observed patterns. Seventy-three bird species were observed exploiting the streets: native species were the most abundant and frequent throughout this landscape. The bird community's functional richness and Rao's Quadratic Entropy presented values lower than 0.5. Therefore, this landscape was favoring few functional traits. Exposure to noise was the most limiting factor for this bird community. However, the average size of arboreal patches and, especially the characteristics of street trees, were able to reduce the negative effects of noise on the bird community. These results show the importance of adequately planning the urban afforestation process: increasing tree species richness, preserving large trees and planting more native trees species in the streets are management practices that will increase bird species richness, abundance and community functional aspects and

  10. A Solution for Street Lighting in Smart Cities

    Directory of Open Access Journals (Sweden)

    M. Popa

    2012-06-01

    Full Text Available Smart Cities is a domain of great interest in the modern society. The aim of a smart urban environment is to increase citizens’ comfort and quality of life with minimum resources and power consumption and without affecting the natural environment. Street lighting is one of the main interests in such a smart environment. This thesis focuses on implementing a lighting control system that makes street lighting to be an autonomous and efficient part of the urban environment. The performance of the proposed system is analyzed using an OMNET++ network simulation. The results lead to the conclusion that the smart control system improves some drawbacks of a classic street lighting system.

  11. Impacts of Street-Visible Greenery on Housing Prices: Evidence from a Hedonic Price Model and a Massive Street View Image Dataset in Beijing

    Directory of Open Access Journals (Sweden)

    Yonglin Zhang

    2018-03-01

    Full Text Available Street greenery is a component of urban green infrastructure. By forming foundational green corridors in urban ecological systems, street greenery provides vital ecological, social, and cultural functions, and benefits the wellbeing of citizens. However, because of the difficulty of quantifying people’s visual perceptions, the impact of street-visible greenery on housing prices has not been fully studied. Using Beijing, which has a mature real estate market, as an example, this study evaluated 22,331 transactions in 2014 in 2370 private housing estates. We selected 25 variables that were classified into three categories—location, housing, and neighbourhood characteristics—and introduced an index called the horizontal green view index (HGVI into a hedonic pricing model to measure the value of the visual perception of street greenery in neighbouring residential developments. The results show that (1 Beijing’s homebuyers would like to reside in residential units with a higher HGVI; (2 Beijing’s homebuyers favour larger lakes; and (3 Beijing’s housing prices were impacted by the spatial development patterns of the city centre and multiple business centres. We used computer vision to quantify the street-visible greenery and estimated the economic benefits that the neighbouring visible greenery would have on residential developments in Beijing. This study provides a scientific basis and reference for policy makers and city planners in road greening, and a tool for formulating street greening policy, studying housing price characteristics, and evaluating real estate values.

  12. Medline Plus

    Full Text Available ... surgical procedures. These are actual operations performed at medical centers in the United States. Please note that ... New Frontier of Coronary Intervention (University of Chicago Medical Center, Chicago, IL, 6/26/2014) Aortic Aneurysm ...

  13. Medline Plus

    Full Text Available ... procedures. These are actual operations performed at medical centers in the United States. Please note that you ... Frontier of Coronary Intervention (University of Chicago Medical Center, Chicago, IL, 6/26/2014) Aortic Aneurysm Hybrid ...

  14. Medline Plus

    Full Text Available ... to disable it to view the programs. Blood, Heart and Circulation Angioplasty Transradial Approach for Cardiac Catheterization: ... Chicago Medical Center, Chicago, IL, 6/26/2014) Heart Diseases Transesophageal Echocardiogram (TEE) (Shawnee Mission Medical Center, ...

  15. Land Use Correlates of Street Children in Ogbomoso, Nigeria

    African Journals Online (AJOL)

    There exist many locations in which street children are found: public spheres such as markets, bus stops, car parks, garages, street corners, and under the bridges .... attributes of space such as form, pattern and aspect and are descriptive in ...

  16. Do urban canyons influence street level grass pollen concentrations?

    DEFF Research Database (Denmark)

    Peel, Robert George; Kennedy, Roy; Smith, Matt

    2014-01-01

    In epidemiological studies, outdoor exposure to pollen is typically estimated using rooftop monitoring station data, whilst exposure overwhelmingly occurs at street level. In this study the relationship between street level and roof level grass pollen concentrations was investigated for city cent...

  17. The role of genetic variation across IL-1β, IL-2, IL-6, and BDNF in antipsychotic-induced weight gain.

    Science.gov (United States)

    Fonseka, Trehani M; Tiwari, Arun K; Gonçalves, Vanessa F; Lieberman, Jeffrey A; Meltzer, Herbert Y; Goldstein, Benjamin I; Kennedy, James L; Kennedy, Sidney H; Müller, Daniel J

    2015-01-01

    Antipsychotics with high weight gain-inducing propensities influence the expression of immune and neurotrophin genes, which have been independently related to obesity indices. Thus, we investigated whether variants in the genes encoding interleukin (IL)-1β, IL-2, and IL-6 and brain-derived neurotrophic factor (BDNF) Val66Met are associated with antipsychotic-induced weight gain (AIWG). Nineteen polymorphisms were genotyped using Taqman(®) assays in 188 schizophrenia patients on antipsychotic treatment for up to 14 weeks. Mean weight change (%) from baseline was compared across genotypic groups using analysis of covariance (ANCOVA). Epistatic effects between cytokine polymorphisms and BDNF Val66Met were tested using Model-Based Multifactor Dimensionality Reduction. In European patients, IL-1β rs16944*GA (P = 0.013, Pcorrected = 0.182), IL-1β rs1143634*G (P = 0.001, Pcorrected = 0.014), and BDNF Val66Met (Val/Val, P = 0.004, Pcorrected = 0.056) were associated with greater AIWG, as were IL-1β rs4849127*A (P = 0.049, Pcorrected = 0.784), and IL-1β rs16944*GA (P = 0.012, Pcorrected = 0.192) in African Americans. BDNF Val66Met interacted with both IL-1β rs13032029 (Val/Met+ TT, PPerm = 0.029), and IL-6 rs2069837 (Val/Val+ AA, PPerm = 0.021) in Europeans, in addition to IL-1β rs16944 (Val/Val+ GA, PPerm = 0.006) in African Americans. SNPs across IL-1β and BDNF Val66Met may influence AIWG. Replication of these findings in larger, independent samples is warranted.

  18. Creating Chicago History: Making Outreach Craft Activities Meaningful

    Science.gov (United States)

    Karp, Madeline

    2012-01-01

    When it comes to having a traveling outreach activity for a museum, a craft can seem like the perfect solution. It can seemingly be all things at once--educational, quick and fun. But, if poorly constructed, crafts can also have serious fallbacks. Using the Chicago History Museum and the Millennium Park Family Fun Festival as a case study, this…

  19. In vitro secretion profiles of interleukin (IL-1beta, IL-6, IL-8, IL-10, and TNF alpha after selective infection with Escherichia coli in human fetal membranes

    Directory of Open Access Journals (Sweden)

    Maida-Claros Rolando

    2007-12-01

    Full Text Available Abstract Background Chorioamniotic membranes infection is a pathologic condition in which an abnormal secretion of proinflammatory cytokines halts fetal immune tolerance. The aim of the present study was to evaluate the functional response of human chorioamniotic membranes, as well as the individual contribution of the amnion and choriodecidua after stimulation with Escherichia coli, a pathogen associated with preterm labor. Methods Explants of chorioamniotic membranes from 10 women (37–40 weeks of gestation were mounted and cultured in a Transwell system, which allowed us to test the amnion and choriodecidua compartments independently. Escherichia coli (1 × 10 6 CFU/mL was added to either the amniotic or the choriodecidual regions or both; after a 24-h incubation, the secretion of IL-1beta, IL-6, TNFalpha, IL-8, and IL-10 in both compartments was measured using a specific ELISA. Data were analyzed by Kruskal-Wallis one-way analysis of variance. Results After stimulation with Escherichia coli, the choriodecidua compartment showed an increase in the secretion of IL-1beta (21-fold, IL-6 (2-fold, IL-8 (6-fold, and IL-10 (37-fold, regardless of which side of the membrane was stimulated; TNFalpha secretion augmented (22-fold also but only when the stimulus was applied simultaneously to both sides. When the amnion was stimulated directly, the level of IL-1beta (13-fold rose significantly; however, the increase in IL-8 secretion was larger (20-fold, regardless of the primary site of infection. TNFalpha secretion in the amnion compartment rose markedly only when Escherichia coli was simultaneously applied to both sides. Conclusion Selective stimulation of fetal membranes with Escherichia coli results in a differential production of IL-1beta, IL-6, TNFalpha, IL-8, and IL-10. These tissues were less responsive when the amnion side was stimulated. This is in agreement with the hypothesis that the choriodecidua may play a primary role during an ascending

  20. Il laser

    CERN Document Server

    Smith, William V

    1974-01-01

    Verso il 1960, il laser era ancora "una soluzione alla ricerca di un problema", ma fin dagli anni immediatamente successivi si è rivelato uno strumento insostituibile per le applicazioni più svariate.

  1. NUTRIENTS INTAKE AND NUTRITIONAL STATUS OF STREET CHILDREN IN BANDUNG

    Directory of Open Access Journals (Sweden)

    Rita Patriasih

    2012-03-01

    Full Text Available 800x600 Normal 0 false false false IN X-NONE X-NONE MicrosoftInternetExplorer4 The objectives of this research were to analyze food habits and nutrients intake, and health and nutritional status of street children. The research was carried out in the City of Bandung, West Java; Indonesia. A sample of 324 street children was selected randomly. The sample consisted of 232 boys and 92 girls. The data obtained from questionnaires. Means, standard deviation, frequency and proportion were calculated with a combination of software applications:  Microsoft Excel and Statistical Analysis System. The result showed the level of consumption adequacy did not meet the recommended dietary allowances i.e. with the shortage of 10-15%, this is an indication that the street children should be aware of their daily food consumption. The most common diseases suffered by the respondents were acute respiratory infections (ARI (47%. In addition, 22.7 % and 18.4 % of them suffered from diarrhoea and skin diseases, respectively. Blood haemoglobin status of street children shows that the incidence of anemia was 29.3%. Based on the classification of nutritional status, 42.7% and 80.4 % of street children were underweight and stunted, respectively. Key words: nutrients intake, nutritional status, street children

  2. Green Street in District of Columbia Curbs Harmful Runoff

    Science.gov (United States)

    The name of the block hasn’t been changed to “Oh!” Street, but a revamped section of O Street NW in the District of Columbia is turning heads with green features that are keeping stormwater pollution out of the Anacostia River.

  3. The levels and patterns of resilience among male street children in Dhaka City.

    Science.gov (United States)

    Sayem, Amir M; Kidd, Sean A

    2013-01-01

    Abstract This study was carried out to identify the factors affecting resilience among street children. The study used a convenience sample of 366 male street children aged 14-17 years in Dhaka City, Bangladesh. The levels of resilience among the street children were mostly moderately low-low (54.1%), followed by low (29.0%), and moderately high-high resilience (16.9%). Multinomial logistic regression analyses indicated that the pre-street factors of education, economic constraint in the family, as well as experiencing and witnessing domestic violence were associated with resilience, with associated street characteristics being drug abuse, experiencing and witnessing violence on street, access to prevention services, and political involvement.

  4. Curcumin blocks interleukin (IL)-2 signaling in T-lymphocytes by inhibiting IL-2 synthesis, CD25 expression, and IL-2 receptor signaling

    International Nuclear Information System (INIS)

    Forward, Nicholas A.; Conrad, David M.; Power Coombs, Melanie R.; Doucette, Carolyn D.; Furlong, Suzanne J.; Lin, Tong-Jun; Hoskin, David W.

    2011-01-01

    Highlights: → Curcumin inhibits CD4 + T-lymphocyte proliferation. → Curcumin inhibits interleukin-2 (IL-2) synthesis and CD25 expression by CD4 + T-lymphocytes. → Curcumin interferes with IL-2 receptor signaling by inhibiting JAK3 and STAT5 phosphorylation. → IL-2-dependent regulatory T-lymphocyte function and Foxp3 expression is downregulated by curcumin. -- Abstract: Curcumin (diferulomethane) is the principal curcuminoid in the spice tumeric and a potent inhibitor of activation-induced T-lymphocyte proliferation; however, the molecular basis of this immunosuppressive effect has not been well studied. Here we show that micromolar concentrations of curcumin inhibited DNA synthesis by mouse CD4 + T-lymphocytes, as well as interleukin-2 (IL-2) and CD25 (α chain of the high affinity IL-2 receptor) expression in response to antibody-mediated cross-linking of CD3 and CD28. Curcumin acted downstream of protein kinase C activation and intracellular Ca 2+ release to inhibit IκB phosphorylation, which is required for nuclear translocation of the transcription factor NFκB. In addition, IL-2-dependent DNA synthesis by mouse CTLL-2 cells, but not constitutive CD25 expression, was impaired in the presence of curcumin, which demonstrated an inhibitory effect on IL-2 receptor (IL-2R) signaling. IL-2-induced phosphorylation of STAT5A and JAK3, but not JAK1, was diminished in the presence of curcumin, indicating inhibition of critical proximal events in IL-2R signaling. In line with the inhibitory action of curcumin on IL-2R signaling, pretreatment of CD4 + CD25 + regulatory T-cells with curcumin downregulated suppressor function, as well as forkhead box p3 (Foxp3) expression. We conclude that curcumin inhibits IL-2 signaling by reducing available IL-2 and high affinity IL-2R, as well as interfering with IL-2R signaling.

  5. 75 FR 6433 - Federal Aviation Administration

    Science.gov (United States)

    2010-02-09

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Availability of a Draft... 9, West Chicago, IL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of... Surveillance Radar, Model 9, West Chicago, Illinois. SUMMARY: The Federal Aviation Administration (FAA...

  6. A bicycle safety index for evaluating urban street facilities.

    Science.gov (United States)

    Asadi-Shekari, Zohreh; Moeinaddini, Mehdi; Zaly Shah, Muhammad

    2015-01-01

    The objectives of this research are to conceptualize the Bicycle Safety Index (BSI) that considers all parts of the street and to propose a universal guideline with microscale details. A point system method comparing existing safety facilities to a defined standard is proposed to estimate the BSI. Two streets in Singapore and Malaysia are chosen to examine this model. The majority of previous measurements to evaluate street conditions for cyclists usually cannot cover all parts of streets, including segments and intersections. Previous models also did not consider all safety indicators and cycling facilities at a microlevel in particular. This study introduces a new concept of a practical BSI to complete previous studies using its practical, easy-to-follow, point system-based outputs. This practical model can be used in different urban settings to estimate the level of safety for cycling and suggest some improvements based on the standards.

  7. Pühendusega isadele - Baker Street

    Index Scriptorium Estoniae

    2009-01-01

    Üritusest 7. novembril Kuressaares Arensburg lounge-restoranis Muusa toimuvast isadepäevahõngulisest üritusest, esinevad Virgo Veldi & Band kavaga "Baker Street", erikülalisena Villu Veski. Saksofonistist Virgo Veldist

  8. Estilo Chicago [Actualización 2017

    OpenAIRE

    Biblioteca Universitaria

    2017-01-01

    Mediante el estudio de este tema aprenderás a gestionar adecuadamente tu bibliografía adquiriendo una serie de competencias que te permitirán: - Actuar de manera responsable, ética y legal en el uso de la información empleada para realizar un trabajo académico. - Identificar el estilo de cita más adecuado para cada disciplina científica. - Identificar correctamente y elaborar las referencias bibliográficas correspondientes a distintos tipos de documentos, de acuerdo con el estilo Chicago. - A...

  9. Cesium-137 in various Chicago foods

    International Nuclear Information System (INIS)

    Karttunen, J.O.

    1979-01-01

    Since April 1961, the 137 Cs and potassium content of the Chicago portion of the Tri-City Diet Sampling Program has been determined in bulk food samples by gamma-ray spectrometry using a 4'' x 4'' NaI (TI) crystal. Each variety of food (all fresh vegetables, all fresh fruit, etc.) is composited before measurement, and each sample is counted 400 to 1000 minutes. From these measurements composite daily and yearly food intakes are obtained. The results for the October 1978 semi-annual sampling are tabulated

  10. Multi-scale modeling of urban air pollution: development of a Street-in-Grid model

    Science.gov (United States)

    Kim, Youngseob; Wu, You; Seigneur, Christian; Roustan, Yelva

    2016-04-01

    A new multi-scale model of urban air pollution is presented. This model combines a chemical-transport model (CTM) that includes a comprehensive treatment of atmospheric chemistry and transport at spatial scales greater than 1 km and a street-network model that describes the atmospheric concentrations of pollutants in an urban street network. The street-network model is based on the general formulation of the SIRANE model and consists of two main components: a street-canyon component and a street-intersection component. The street-canyon component calculates the mass transfer velocity at the top of the street canyon (roof top) and the mean wind velocity within the street canyon. The estimation of the mass transfer velocity depends on the intensity of the standard deviation of the vertical velocity at roof top. The effect of various formulations of this mass transfer velocity on the pollutant transport at roof-top level is examined. The street-intersection component calculates the mass transfer from a given street to other streets across the intersection. These mass transfer rates among the streets are calculated using the mean wind velocity calculated for each street and are balanced so that the total incoming flow rate is equal to the total outgoing flow rate from the intersection including the flow between the intersection and the overlying atmosphere at roof top. In the default option, the Leighton photostationary cycle among ozone (O3) and nitrogen oxides (NO and NO2) is used to represent the chemical reactions within the street network. However, the influence of volatile organic compounds (VOC) on the pollutant concentrations increases when the nitrogen oxides (NOx) concentrations are low. To account for the possible VOC influence on street-canyon chemistry, the CB05 chemical kinetic mechanism, which includes 35 VOC model species, is implemented in this street-network model. A sensitivity study is conducted to assess the uncertainties associated with the use of

  11. Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2.

    Science.gov (United States)

    Popovic, B; Breed, J; Rees, D G; Gardener, M J; Vinall, L M K; Kemp, B; Spooner, J; Keen, J; Minter, R; Uddin, F; Colice, G; Wilkinson, T; Vaughan, T; May, R D

    2017-01-20

    Interleukin (IL)-13 is a pleiotropic T helper type 2 cytokine frequently associated with asthma and atopic dermatitis. IL-13-mediated signalling is initiated by binding to IL-13Rα1, which then recruits IL-4Rα to form a heterodimeric receptor complex. IL-13 also binds to IL-13Rα2, considered as either a decoy or a key mediator of fibrosis. IL-13-neutralising antibodies act by preventing IL-13 binding to IL-13Rα1, IL-4Rα and/or IL-13Rα2. Tralokinumab (CAT-354) is an IL-13-neutralising human IgG4 monoclonal antibody that has shown clinical benefit in patients with asthma. To decipher how tralokinumab inhibits the effects of IL-13, we determined the structure of tralokinumab Fab in complex with human IL-13 to 2 Å resolution. The structure analysis reveals that tralokinumab prevents IL-13 from binding to both IL-13Rα1 and IL-13Rα2. This is supported by biochemical ligand-receptor interaction assay data. The tralokinumab epitope is mainly composed of residues in helices D and A of IL-13. It is mostly light chain complementarity-determining regions that are driving paratope interactions; the variable light complementarity-determining region 2 plays a key role by providing residue contacts for a network of hydrogen bonds and a salt bridge in the core of binding. The key residues within the paratope contributing to binding were identified as Asp50, Asp51, Ser30 and Lys31. This study demonstrates that tralokinumab prevents the IL-13 pharmacodynamic effect by binding to IL-13 helices A and D, thus preventing IL-13 from interacting with IL-13Rα1 and IL-13Rα2. Copyright © 2016 AstraZeneca. Published by Elsevier Ltd.. All rights reserved.

  12. Association study of IL10 and IL23R-IL12RB2 in Iranian patients with Behçet's disease.

    Science.gov (United States)

    Xavier, Joana M; Shahram, Farhad; Davatchi, Fereydoun; Rosa, Alexandra; Crespo, Jorge; Abdollahi, Bahar Sadeghi; Nadji, Abdolhadi; Jesus, Gorete; Barcelos, Filipe; Patto, José Vaz; Shafiee, Niloofar Mojarad; Ghaderibarim, Fahmida; Oliveira, Sofia A

    2012-08-01

    Independent replication of the findings from genome-wide association studies (GWAS) remains the gold standard for results validation. Our aim was to test the association of Behçet's disease (BD) with the interleukin-10 gene (IL10) and the IL-23 receptor-IL-12 receptor β2 (IL23R-IL12RB2) locus, each of which has been previously identified as a risk factor for BD in 2 different GWAS. Six haplotype-tagging single-nucleotide polymorphisms (SNPs) in IL10 and 42 in IL23R-IL12RB2 were genotyped in 973 Iranian patients with BD and 637 non-BD controls. Population stratification was assessed using a panel of 86 ancestry-informative markers. Subtle evidence of population stratification was found in our data set. In IL10, rs1518111 was nominally associated with BD before and after adjustment for population stratification (odds ratio [OR] for T allele 1.20, 95% confidence interval [95% CI] 1.02-1.40, unadjusted P [P(unadj) ] = 2.53 × 10(-2) ; adjusted P [P(adj) ] = 1.43 × 10(-2) ), and rs1554286 demonstrated a trend toward association (P(unadj) = 6.14 × 10(-2) ; P(adj) = 3.21 × 10(-2) ). Six SNPs in IL23R-IL12RB2 were found to be associated with BD after Bonferroni correction for multiple testing, the most significant of which were rs17375018 (OR for G allele 1.51, 95% CI 1.27-1.78, P(unadj) = 1.93 × 10(-6) ), rs7517847 (OR for T allele 1.48, 95% CI 1.26-1.74, P(unadj) = 1.23 × 10(-6) ), and rs924080 (OR for T allele 1.29, 95% CI 1.20-1.39, P = 1.78 × 10(-5) ). SNPs rs10489629, rs1343151, and rs1495965 were also significantly associated with BD in all tests performed. Results of meta-analyses of our data combined with data from other populations further confirmed the role of rs1518111, rs17375018, rs7517847, and rs924080 in the risk of BD, but no epistatic interactions between IL10 and IL23R-IL12RB2 were detected. Results of imputation analysis highlighted the importance of IL23R regulatory regions in the susceptibility to BD. These findings independently confirm

  13. Xinjiang Studies: The Third Wave

    Directory of Open Access Journals (Sweden)

    Peter C. Perdue

    2016-12-01

    Full Text Available Kwangmin Kim. Borderland Capitalism: Turkestan Produce, Qing Silver, and the Birth of an Eastern Market. Stanford, CA: Stanford University Press, 2016. 312 pp. $65 (cloth. Rian Thum. The Sacred Routes of Uyghur History. Cambridge, MA: Harvard University Press, 2014. 336 pp. $40 (cloth. David J. Brophy. Uyghur Nation: Reform and Revolution on the Russia-China Frontier. Cambridge, MA: Harvard University Press, 2016. 368 pp. $40 (cloth. Judd Kinzley. Production and Power in China’s Far West: Gold, Wool, and Oil in the Transformation of Xinjiang, 1893–1965. Chicago, IL: University of Chicago Press, forthcoming. Justin M. Jacobs. Xinjiang and the Modern Chinese State. Seattle: University of Washington Press, 2016. 320 pp. $50 (cloth. Tom Cliff. Oil and Water: Being Han in Xinjiang. Chicago, IL: University of Chicago Press, 2016. 280 pp. $90 (cloth; $30 (paper/e-book.

  14. 77 FR 25595 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2012-05-01

    ... Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal... Safety Zone; Brandon Road Lock and [[Page 25596

  15. Clinical significance of determination of changes in serum hs-CRP, IL-6, IL-10, and IL-18 levels after treatment in patients with acute conjunctivitis

    International Nuclear Information System (INIS)

    Liu Jun

    2007-01-01

    Objective: To study the clinical significance of changes of serum hs-CRP, IL-6, IL-10 and IL-18 levels in patients with acute conjunctivitis after treatment. Methods: Serum IL-6, IL-10 (with RIA) hs-CRP (with Immuno-turbidity) and IL-18 (with ELISA) levels were measured in 38 patients with acute conjunctivitis both before and after treatment as well as in 35 controls. Results: The serum hs-CRP, IL-6, IL-10 and IL-18 levels in the patients before treatment were significantly higher than those in the controls (P 0.05). Conclusion: Measurement of the changes of serum hs-CRP, IL-6, IL-10 and IL-18 levels after treatment might be inportant for outcome prediction in patients with acute conjunctivitis. (authors)

  16. Smart street lighting management

    Energy Technology Data Exchange (ETDEWEB)

    Pizzuti, S.; Annunziato, M. [Energy New Technologies and Sustainable Economic Development Agency ENEA, Rome (Italy); Moretti, F. [Automation and Computer Science Department, University & #x27; Roma Tre& #x27; , Rome (Italy)

    2013-08-15

    In this work, we propose a new street lighting energy management system in order to reduce energy consumption. The key idea we want to accomplish is that of 'energy on demand' meaning that energy, in this case light, is provided only when needed. In order to achieve this goal, it is critical to have a reliable demand model, which in the case of street lighting turns out to be a traffic flow rate forecasting model. In order to achieve this goal, several methods on the 1-h prediction have been compared and the one providing the best results is based on artificial neural networks. Moreover, several control strategies have been tested and the one which gave the best energy savings is the adaptive one we carried out. Experimentation has been carried out on real data and the study shows that with the proposed approach, it is possible to save up to 50 % of energy compared to no regulation systems.

  17. Playing Sport In The Stormy Sea Of Street Life | Human | African ...

    African Journals Online (AJOL)

    Currently, there are many street children in South Africa (SA). They have been robbed from the safe harbour of family life and on a daily basis experience the stormy sea of street life. Society has an obligation to intervene in the lives of these street children through, for example, quality education, basic health services and ...

  18. IL-17 mediates immunopathology in the absence of IL-10 following Leishmania major infection.

    Directory of Open Access Journals (Sweden)

    Claudia Gonzalez-Lombana

    2013-03-01

    Full Text Available Leishmaniasis, resulting from infection with the protozoan parasite Leishmania, consists of a wide spectrum of clinical manifestations, from healing cutaneous lesions to fatal visceral infections. A particularly severe form of cutaneous leishmaniasis, termed mucosal leishmaniasis, exhibits decreased IL-10 levels and an exaggerated inflammatory response that perpetuates the disease. Using a mouse model of leishmaniasis, we investigated what cytokines contribute to increased pathology when IL-10-mediated regulation is absent. Leishmania major infected C57BL/6 mice lacking IL-10 regulation developed larger lesions than controls, but fewer parasites. Both IFN-γ and IL-17 levels were substantially elevated in mice lacking the capacity to respond to IL-10. IFN-γ promoted an increased infiltration of monocytes, while IL-17 contributed to an increase in neutrophils. Surprisingly, however, we found that IFN-γ did not contribute to increased pathology, but instead regulated the IL-17 response. Thus, blocking IFN-γ led to a significant increase in IL-17, neutrophils and disease. Similarly, the production of IL-17 by cells from leishmaniasis patients was also regulated by IL-10 and IFN-γ. Additional studies found that the IL-1 receptor was required for both the IL-17 response and increased pathology. Therefore, we propose that regulating IL-17, possibly by downregulating IL-1β, may be a useful approach for controlling immunopathology in leishmaniasis.

  19. 78 FR 29763 - Final Flood Hazard Determinations

    Science.gov (United States)

    2013-05-21

    ... newspapers of local circulation and ninety (90) days have elapsed since that publication. The Deputy... School Street, Fisher, IL 61843. Village of Ivesdale Village Hall, 406 Third Street, Ivesdale, IL 61851...

  20. Travel Time Estimation on Urban Street Segment

    Directory of Open Access Journals (Sweden)

    Jelena Kajalić

    2018-02-01

    Full Text Available Level of service (LOS is used as the main indicator of transport quality on urban roads and it is estimated based on the travel speed. The main objective of this study is to determine which of the existing models for travel speed calculation is most suitable for local conditions. The study uses actual data gathered in travel time survey on urban streets, recorded by applying second by second GPS data. The survey is limited to traffic flow in saturated conditions. The RMSE method (Root Mean Square Error is used for research results comparison with relevant models: Akcelik, HCM (Highway Capacity Manual, Singapore model and modified BPR (the Bureau of Public Roads function (Dowling - Skabardonis. The lowest deviation in local conditions for urban streets with standardized intersection distance (400-500 m is demonstrated by Akcelik model. However, for streets with lower signal density (<1 signal/km the correlation between speed and degree of saturation is best presented by HCM and Singapore model. According to test results, Akcelik model was adopted for travel speed estimation which can be the basis for determining the level of service in urban streets with standardized intersection distance and coordinated signal timing under local conditions.

  1. Pecan Street Grid Demonstration Program. Final technology performance report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-02-10

    This document represents the final Regional Demonstration Project Technical Performance Report (TPR) for Pecan Street Inc.’s (Pecan Street) Smart Grid Demonstration Program, DE-OE-0000219. Pecan Street is a 501(c)(3) smart grid/clean energy research and development organization headquartered at The University of Texas at Austin (UT). Pecan Street worked in collaboration with Austin Energy, UT, Environmental Defense Fund (EDF), the City of Austin, the Austin Chamber of Commerce and selected consultants, contractors, and vendors to take a more detailed look at the energy load of residential and small commercial properties while the power industry is undergoing modernization. The Pecan Street Smart Grid Demonstration Program signed-up over 1,000 participants who are sharing their home or businesses’s electricity consumption data with the project via green button protocols, smart meters, and/or a home energy monitoring system (HEMS). Pecan Street completed the installation of HEMS in 750 homes and 25 commercial properties. The program provided incentives to increase the installed base of roof-top solar photovoltaic (PV) systems, plug-in electric vehicles with Level 2 charging, and smart appliances. Over 200 participants within a one square mile area took advantage of Austin Energy and Pecan Street’s joint PV incentive program and installed roof-top PV as part of this project. Of these homes, 69 purchased or leased an electric vehicle through Pecan Street’s PV rebate program and received a Level 2 charger from Pecan Street. Pecan Street studied the impacts of these technologies along with a variety of consumer behavior interventions, including pricing models, real-time feedback on energy use, incentive programs, and messaging, as well as the corresponding impacts on Austin Energy’s distribution assets.The primary demonstration site was the Mueller community in Austin, Texas. The Mueller development, located less than three miles from the Texas State Capitol

  2. Medline Plus

    Full Text Available ... Chicago Medical Center, Chicago, IL, 6/26/2014) Heart Diseases Transesophageal Echocardiogram (TEE) (Shawnee Mission Medical Center, Merriam, ... Callahan Eye Hospital, Birmingham, AL, 3/17/2014) Heart Diseases Transesophageal Echocardiogram (TEE) (Shawnee Mission Medical Center, Merriam, ...

  3. Interleukin-33 (IL-33): A nuclear cytokine from the IL-1 family.

    Science.gov (United States)

    Cayrol, Corinne; Girard, Jean-Philippe

    2018-01-01

    Interleukin-33 (IL-33) is a tissue-derived nuclear cytokine from the IL-1 family abundantly expressed in endothelial cells, epithelial cells and fibroblast-like cells, both during homeostasis and inflammation. It functions as an alarm signal (alarmin) released upon cell injury or tissue damage to alert immune cells expressing the ST2 receptor (IL-1RL1). The major targets of IL-33 in vivo are tissue-resident immune cells such as mast cells, group 2 innate lymphoid cells (ILC2s) and regulatory T cells (Tregs). Other cellular targets include T helper 2 (Th2) cells, eosinophils, basophils, dendritic cells, Th1 cells, CD8 + T cells, NK cells, iNKT cells, B cells, neutrophils and macrophages. IL-33 is thus emerging as a crucial immune modulator with pleiotropic activities in type-2, type-1 and regulatory immune responses, and important roles in allergic, fibrotic, infectious, and chronic inflammatory diseases. The critical function of IL-33/ST2 signaling in allergic inflammation is illustrated by the fact that IL33 and IL1RL1 are among the most highly replicated susceptibility loci for asthma. In this review, we highlight 15 years of discoveries on IL-33 protein, including its molecular characteristics, nuclear localization, bioactive forms, cellular sources, mechanisms of release and regulation by proteases. Importantly, we emphasize data that have been validated using IL-33-deficient cells. © 2017 The Authors. Immunological Reviews Published by John Wiley & Sons Ltd.

  4. Evaluation of impacts of trees on PM2.5 dispersion in urban streets

    Science.gov (United States)

    Jin, Sijia; Guo, Jiankang; Wheeler, Stephen; Kan, Liyan; Che, Shengquan

    2014-12-01

    Reducing airborne particulate matter (PM), especially PM2.5 (PM with aerodynamic diameters of 2.5 μm or less), in urban street canyons is critical to the health of central city population. Tree-planting in urban street canyons is a double-edged sword, providing landscape benefits while inevitably resulting in PM2.5 concentrating at street level, thus showing negative environmental effects. Thereby, it is necessary to quantify the impact of trees on PM2.5 dispersion and obtain the optimum structure of street trees for minimizing the PM2.5 concentration in street canyons. However, most of the previous findings in this field were derived from wind tunnel or numerical simulation rather than on-site measuring data. In this study, a seasonal investigation was performed in six typical street canyons in the residential area of central Shanghai, which has been suffering from haze pollution while having large numbers of green streets. We monitored and measured PM2.5 concentrations at five heights, structural parameters of street trees and weather. For tree-free street canyons, declining PM2.5 concentrations were found with increasing height. However, in presence of trees the reduction rate of PM2.5 concentrations was less pronounced, and for some cases, the concentrations even increased at the top of street canyons, indicating tree canopies are trapping PM2.5. To quantify the decrease of PM2.5 reduction rate, we developed the attenuation coefficient of PM2.5 (PMAC). The wind speed was significantly lower in street canyons with trees than in tree-free ones. A mixed-effects model indicated that canopy density (CD), leaf area index (LAI), rate of change of wind speed were the most significant predictors influencing PMAC. Further regression analysis showed that in order to balance both environmental and landscape benefits of green streets, the optimum range of CD and LAI was 50%-60% and 1.5-2.0 respectively. We concluded by suggesting an optimized tree-planting pattern and

  5. A Brief History of IL-1 and IL-1 Ra in Rheumatology

    Directory of Open Access Journals (Sweden)

    Jean-Michel Dayer

    2017-05-01

    Full Text Available The history of what, in 1979, was called interleukin-1 (IL-1, orchestrator of leukocyte inter-communication, began many years before then, initially by the observation of fever induction via the endogenous pyrogen (EP (1974 and then in rheumatology on the role in tissue destruction in rheumatoid diseases via the induction of collagenase and PGE2 in human synovial cells by a mononuclear cell factor (MCF (1977. Since then, the family has exploded to presently 11 members as well as many membrane-bound and soluble receptor forms. The discovery of a natural Interleukin-1 receptor antagonist (IL-1Ra in human biological fluids has highlighted the importance of IL-1 and IL-1Ra in human diseases. Evidence delineating its role in autoinflammatory syndromes and the elucidation of the macromolecular complex referred to as “inflammasome” have been instrumental to our understanding of the link with IL-1. At present, the IL-1blockade as therapeutic approach is crucial for many hereditary autoinflammatory diseases, as well as for adult-onset Still’s disease, crystal-induced arthropathies, certain skin diseases including neutrophil-triggered skin diseases, Behçet’s disease and deficiency of IL-1Ra and other rare fever syndromes. Its role is only marginally important in rheumatoid arthritis and is still under debate with regard to osteoarthritis, type 2 diabetes mellitus, cardiovascular diseases and cancer. This brief historical review focuses on some aspects of IL-1, mainly IL-1β and IL-Ra, in rheumatology. There are many excellent reviews focusing on the IL-1 family in general or with regard to specific diseases or biological discoveries.

  6. Hepatitis B virus induces IL-23 production in antigen presenting cells and causes liver damage via the IL-23/IL-17 axis.

    Directory of Open Access Journals (Sweden)

    Qinghong Wang

    Full Text Available IL-23 regulates myriad processes in the innate and adaptive immune systems, and is a critical mediator of the proinflammatory effects exerted by Th17 cells in many diseases. In this study, we investigated whether and how hepatitis B virus (HBV causes liver damage directly through the IL-23 signaling pathway. In biopsied liver tissues from HBV-infected patients, expression of both IL-23 and IL-23R was remarkably elevated. In vivo observations also indicated that the main sources of IL-23 were myeloid dendritic cells (mDCs and macrophages. Analysis of in vitro differentiated immature DCs and macrophages isolated from healthy donors revealed that the HBV surface antigen (HBsAg efficiently induces IL-23 secretion in a mannose receptor (MR-dependent manner. Culture with an endosomal acidification inhibitor and the dynamin inhibitor showed that, upon binding to the MR, the HBsAg is taken up by mDCs and macrophages through an endocytosis mechanism. In contrast, although the HBV core antigen (HBcAg can also stimulate IL-23 secretion from mDCs, the process was MR- and endocytosis-independent. In addition, IL-23 was shown to be indispensible for HBsAg-stimulated differentiation of naïve CD4(+ T cells into Th17 cells, which were determined to be the primary source of IL-17 in HBV-infected livers. The cognate receptor, IL-17R, was found to exist on the hepatic stellate cells and mDCs, both of which might represent the potential target cells of IL-17 in hepatitis B disease. These data provide novel insights into a yet unrecognized mechanism of HBV-induced hepatitis, by which increases in IL-23 expression, through an MR/endocytosis-dependent or -independent manner, produce liver damage through the IL-23/IL-17 axis.

  7. Farming Chicago: Prospects for Higher Education Support of Sustainable Urban Food Systems in the U.S. Heartland

    Science.gov (United States)

    Rosing, Howard; Block, Daniel R.

    2017-01-01

    The article highlights recent food policies in Chicago with the goal of exploring how higher education institutions can contribute to development of sustainable food resources for residents of North American cities. Thousands of Chicago residents face daily challenges accessing fresh food due to income constraints and/or lack of proximity to food…

  8. IL-25 or IL-17E protects against high-fat diet-induced hepatic steatosis in mice dependent upon IL-13 activation of STAT6

    Science.gov (United States)

    IL-25 is a member of IL-17 cytokine family and has immune-modulating activities. The role of IL-25 in maintaining lipid metabolic homeostasis remains unknown. Here, we investigated the effects of exogenous IL-25 or deficiency of IL-25 on lipid accumulation in the liver. Mice were injected with IL-25...

  9. The IL-17F/IL-17RC Axis Promotes Respiratory Allergy in the Proximal Airways

    Directory of Open Access Journals (Sweden)

    Antonella De Luca

    2017-08-01

    Full Text Available The interleukin 17 (IL-17 cytokine and receptor family is central to antimicrobial resistance and inflammation in the lung. Mice lacking IL-17A, IL-17F, or the IL-17RA subunit were compared with wild-type mice for susceptibility to airway inflammation in models of infection and allergy. Signaling through IL-17RA was required for efficient microbial clearance and prevention of allergy; in the absence of IL-17RA, signaling through IL-17RC on epithelial cells, predominantly by IL-17F, significantly exacerbated lower airway Aspergillus or Pseudomonas infection and allergic airway inflammation. In contrast, following infection with the upper respiratory pathogen Staphylococcus aureus, the IL-17F/IL-17RC axis mediated protection. Thus, IL-17A and IL-17F exert distinct biological effects during pulmonary infection; the IL-17F/IL-17RC signaling axis has the potential to significantly worsen pathogen-associated inflammation of the lower respiratory tract in particular, and should be investigated further as a therapeutic target for treating pathological inflammation in the lung.

  10. Beyond discourse and competence : Science and subjugated knowledge in street children studies

    NARCIS (Netherlands)

    Gigengack, Roy

    2014-01-01

    This article argues that street children studies (SCS) has reduced its central concept to a discursive construct, and the young street people themselves to capable 'agents'. One consequence is that street children are not recognized as distinct intergenerational groupings in society. The traditional

  11. Solar charge controller in solar street light

    OpenAIRE

    Dong, Haibo

    2014-01-01

    Recently, with the rapid development of scientific technology, the conventional energy cannot meet the requirement of human beings. People are looking for the utilization of renew energy. Solar en-ergy as a new clean energy has attract the eyes of people. The applications of solar energy are popular to human society. Solar street light is a good example. This thesis will focus on a deeper research of the popular and ubiquitous solar street light in China. However, solar charge controll...

  12. HIV knowledge and sexual risk behavior among street adolescents ...

    African Journals Online (AJOL)

    HIV knowledge and sexual risk behavior among street adolescents in rehabilitation centres in Kinshasa; DRC: gender differences. ... Background: Street children, common in Africa, are increasingly vulnerable to alcohol and drugs of abuse and lack access to both healthcare and knowledge about HIV and AIDS. Hence, this ...

  13. 77 FR 67689 - Fidelity Aberdeen Street Trust, et al.;

    Science.gov (United States)

    2012-11-13

    ...] Fidelity Aberdeen Street Trust, et al.; Notice of Application November 6, 2012. AGENCY: Securities and... arrangements (``Prior Order'').\\1\\ \\1\\ Colchester Street Trust, et al., Investment Company Act Release Nos... Trust, et al., Investment Company Act Release Nos. 23787 (Apr. 15, 1999) (notice) and 23831 (May 11...

  14. Curcumin blocks interleukin (IL)-2 signaling in T-lymphocytes by inhibiting IL-2 synthesis, CD25 expression, and IL-2 receptor signaling

    Energy Technology Data Exchange (ETDEWEB)

    Forward, Nicholas A.; Conrad, David M. [Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia (Canada); Power Coombs, Melanie R.; Doucette, Carolyn D. [Department of Pathology, Dalhousie University, Halifax, Nova Scotia (Canada); Furlong, Suzanne J. [Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia (Canada); Lin, Tong-Jun [Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia (Canada); Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia (Canada); Hoskin, David W., E-mail: d.w.hoskin@dal.ca [Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia (Canada); Department of Pathology, Dalhousie University, Halifax, Nova Scotia (Canada); Department of Surgery, Dalhousie University, Halifax, Nova Scotia (Canada)

    2011-04-22

    Highlights: {yields} Curcumin inhibits CD4{sup +} T-lymphocyte proliferation. {yields} Curcumin inhibits interleukin-2 (IL-2) synthesis and CD25 expression by CD4{sup +} T-lymphocytes. {yields} Curcumin interferes with IL-2 receptor signaling by inhibiting JAK3 and STAT5 phosphorylation. {yields} IL-2-dependent regulatory T-lymphocyte function and Foxp3 expression is downregulated by curcumin. -- Abstract: Curcumin (diferulomethane) is the principal curcuminoid in the spice tumeric and a potent inhibitor of activation-induced T-lymphocyte proliferation; however, the molecular basis of this immunosuppressive effect has not been well studied. Here we show that micromolar concentrations of curcumin inhibited DNA synthesis by mouse CD4{sup +} T-lymphocytes, as well as interleukin-2 (IL-2) and CD25 ({alpha} chain of the high affinity IL-2 receptor) expression in response to antibody-mediated cross-linking of CD3 and CD28. Curcumin acted downstream of protein kinase C activation and intracellular Ca{sup 2+} release to inhibit I{kappa}B phosphorylation, which is required for nuclear translocation of the transcription factor NF{kappa}B. In addition, IL-2-dependent DNA synthesis by mouse CTLL-2 cells, but not constitutive CD25 expression, was impaired in the presence of curcumin, which demonstrated an inhibitory effect on IL-2 receptor (IL-2R) signaling. IL-2-induced phosphorylation of STAT5A and JAK3, but not JAK1, was diminished in the presence of curcumin, indicating inhibition of critical proximal events in IL-2R signaling. In line with the inhibitory action of curcumin on IL-2R signaling, pretreatment of CD4{sup +}CD25{sup +} regulatory T-cells with curcumin downregulated suppressor function, as well as forkhead box p3 (Foxp3) expression. We conclude that curcumin inhibits IL-2 signaling by reducing available IL-2 and high affinity IL-2R, as well as interfering with IL-2R signaling.

  15. Chicago to Iowa City intercity passenger rail route : business plan.

    Science.gov (United States)

    2011-03-21

    This business plan describes the methods by which the Iowa Department of Transportation (DOT will partner with Iowa counties and cities to fund Iowas share of the operating and maintenance cost for the Chicago-Iowa City passenger-rail service, an ...

  16. A Numerical Simulation of Traffic-Related Air Pollution Exposures in Urban Street Canyons

    Science.gov (United States)

    Liu, J.; Fu, X.; Tao, S.

    2016-12-01

    Urban street canyons are usually associated with intensive vehicle emissions. However, the high buildings successively along both sides of a street block the dispersion of traffic-generated air pollutants, which enhances human exposure and adversely affects human health. In this study, an urban scale traffic pollution dispersion model is developed with the consideration of street distribution, canyon geometry, background meteorology, traffic assignment, traffic emissions and air pollutant dispersion. Vehicle exhausts generated from traffic flows will first disperse inside a street canyon along the micro-scale wind field (generated by computational fluid dynamics (CFD) model) and then leave the street canyon and further disperse over the urban area. On the basis of this model, the effects of canyon geometry on the distribution of NOx and CO from traffic emissions were studied over the center of Beijing, China. We found that an increase of building height along the streets leads to higher pollution levels inside streets and lower pollution levels outside, resulting in higher domain-averaged concentrations over the area. In addition, street canyons with equal (or highly uneven) building heights on two sides of a street tend to lower the urban-scale air pollution concentrations at pedestrian level. Our results indicate that canyon geometry strongly influences human exposure to traffic pollutants in the populated urban area. Carefully planning street layout and canyon geometry in consideration of traffic demand as well as local weather pattern may significantly reduce the chances of unhealthy air being inhaled by urban residents.

  17. Beyond discourse and competence: Science and subjugated knowledge in street children studies

    NARCIS (Netherlands)

    Gigengack, R.A.

    2014-01-01

    This article argues that street children studies (SCS) has reduced its central concept to a discursive construct, and the young street people themselves to capable ‘agents’. One consequence is that street children are not recognized as distinct intergenerational groupings in society. The traditional

  18. Lacrimal gland-derived IL-22 regulates IL-17-mediated ocular mucosal inflammation

    Science.gov (United States)

    Ji, Yong Woo; Mittal, Sharad K.; Hwang, Ho Sik; Chang, Eun-Ju; Lee, Joon H.; Seo, Yuri; Yeo, Areum; Noh, Hyemi; Lee, Hye Sun; Chauhan, Sunil K.; Lee, Hyung Keun

    2016-01-01

    Inflammatory damage of mucosal surface of the eye is a hallmark of dry eye disease (DED), and in severe cases can lead to significant discomfort, visual impairment, and blindness. DED is a multifactorial autoimmune disorder with a largely unknown pathogenesis. Using a cross-sectional patient study and a well-characterized murine model of DED, herein we investigated the immunoregulatory function of interleukin-22 (IL-22) in the pathogenesis of DED. We found that IL-22 levels were elevated in lacrimal fluids of DED patients and inversely correlated with severity of disease. Acinar cells of the lacrimal glands, not inflammatory immune cells, are the primary source of IL-22, which suppresses inflammation in ocular surface epithelial cells upon desiccating stress. Moreover, loss of function analyses using IL-22 knock-out mice demonstrated that IL-22 is essential for suppression of ocular surface infiltration of Th17 cells and inhibition of DED induction. Our novel findings elucidate immunoregulatory function of lacrimal gland-derived IL-22 in inhibiting IL-17-mediated ocular surface epitheliopathy in DED thus making IL-22 a new relevant therapeutic target. PMID:28051088

  19. Rates of firearm homicide by Chicago region, age, sex, and race/ethnicity, 2005-2010.

    Science.gov (United States)

    Walker, Garth Nyambi; McLone, Suzanne; Mason, Maryann; Sheehan, Karen

    2016-10-01

    The United States reports the highest levels of firearm homicide incidences compared to other high income countries, and the focus and causes of these incidences within the US differ by demographic characteristics and location such as urban versus rural environment. Despite these findings, few studies have published on rates varied by region within a city. This study aims to provide descriptive analysis of the rates of firearm homicide by age, sex, and race/ethnicity in each of the seven City of Chicago regions, and to determine if the rates of firearm homicide differ by demographics among the seven City of Chicago regions. The Illinois Violent Death Reporting System conducts routine surveillance of violent deaths. Decedents were selected according to the following criteria: manner of death was homicide, weapon type was firearm, and location of injury that led to death was the City of Chicago. Location of injury was broken down by regions: North, Northwest, Center, West, South, Southwest, and Far South. Multiyear rates per 100,000 and corresponding 95% confidence intervals were calculated. There were 2,254 victims of homicide by firearm in the City of Chicago. The overall rate across Chicago for all demographics was 12.9 (12.1-13.5 per 100,000) with an average age of 27.4. The highest age group (20-24) for firearm homicide rates was 43.2 (39.7-46.7) per 100,000. For the youngest age group (10-14), only the Southwest (3.3-10.4) region reported any firearm incidence. The 20 to 24 age group reported the highest rates of all age groups within the South (107.9-151.7), West (80.3-108.2), and Far South (69.6-105.3) regions, whereas the North and Northwest reported the lowest rates for all regions by age. Black firearm homicide rates were 33.5 (31.9-35.1) per 100,000 versus Hispanic and non-Hispanic white firearm homicide rates of 8.5 (7.7-9.3) and 1.2 (1-1.5) per 100,000, respectively. Lastly, the West reported the highest firearm rates at 29.1 (657). In conclusion

  20. Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing.

    Science.gov (United States)

    Clancy, Danielle M; Sullivan, Graeme P; Moran, Hannah B T; Henry, Conor M; Reeves, Emer P; McElvaney, Noel G; Lavelle, Ed C; Martin, Seamus J

    2018-03-13

    Neutrophil granule proteases are thought to function as anti-microbial effectors, cooperatively hydrolyzing microorganisms within phagosomes, or upon deployment into the extracellular space. However, evidence also suggests that neutrophil proteases play an important role in the coordination and escalation of inflammatory reactions, but how this is achieved has been obscure. IL-1 family cytokines are important initiators of inflammation and are typically released via necrosis but require proteolytic processing for activation. Here, we show that proteases liberated from activated neutrophils can positively or negatively regulate the activity of six IL-1 family cytokines (IL-1α, IL-1β, IL-33, IL-36α, IL-36β, and IL-36γ) with exquisite sensitivity. In contrast, extracellular neutrophil proteases displayed very poor bactericidal activity, exhibiting 100-fold greater potency toward cytokine processing than bacterial killing. Thus, in addition to their classical role as phagocytes, neutrophils play an important immunoregulatory role through deployment of their granule proteases into the extracellular space to process multiple IL-1 family cytokines. Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.

  1. The role of CD40L, IL-10 and IL-17 in radioprotection

    International Nuclear Information System (INIS)

    Li Ting

    2003-01-01

    CD40L/CD40 interaction is central to the control of thymus-dependent humoral immunity and cell mediated immune responses. IL-17 has been shown to induce the production of IL-6 and G-CSF, which can induce proliferation and differentiation of CD34 + hematopoietic progenitors. IL-10 can interfere with up-regulation of costimulatory molecules, thus suppressing the production of costimulatory cytokines, such as IL-12. IL-10 has been implicated as an essential mediator in the induction of systemic immune suppression following ultraviolet (UV) exposure. Treating UV-irradiated mice with anti-IL-10 blocks the induction of immune suppression

  2. An Analysis of the Street-Children Phenomenon in the City of Isfahan

    OpenAIRE

    Seyed Alireza Afshani; Abbas Askari-Nodoushan; Mohammad Heydari; Mohammad Noorian Najafabadi

    2013-01-01

    Introduction   In nearly all big cities around the world, the phenomenon of street children is one of the contemporary social issues. During past several decades, there is an increase in the volume of street children phenomenon around the world. The rising number of street children has many pathological and consequential negative impacts for children, youth, families, and the society at the whole . According to 2000 UN report, the number of street children is estimated between 100 to140 milli...

  3. An investigation on the effect of street morphology to ambient air quality using six real-world cases

    Science.gov (United States)

    Shen, Jialei; Gao, Zhi; Ding, Wowo; Yu, Ying

    2017-09-01

    Street canyons are vulnerable to air pollution mainly caused by vehicle emissions, which are therefore closely related to pedestrians' health. Previous studies have showed that air quality in street canyons is associated with street morphology, though the majority of them have focused on idealized street models. This paper attempts to investigate the relationship of street morphology to air quality for 6 irregular real-world cases selected from America, Europe, and China, i.e. Manhattan, Paris, Barcelona, Berlin, London and Nanjing. Each street is analyzed as a set of slices to propose a couple of morphology indices for quantitatively assessing the actual street morphology. Pollutant transport rate of mean flows and turbulent diffusion, net escape velocity and age of air are obtained from computational fluid dynamics (CFD) simulations to assess the ventilations and pollutant dispersion within street canyons with a parallel approaching wind. The results show that the street morphology characteristics, including the street width, lateral openings and intersections, are closely related to the air flows in street canyons. The air quality improves with a decreasing aspect ratio of central street owing to a larger vertical exchange through the street roof, which suggests an open central street is of better air quality. The lateral openings and intersections of streets have important effects on the air flows in street canyons, and the effects are particularly pronounced when the street widths are similar. The street continuity ratio indicates street continuity. It relates to the openings and the symmetry of a street and impacts on the air flows and pollutant dispersion through the lateral openings of the central street. The street spatial closure ratio is determined by the street continuity ratio and the aspect ratio of the central street. When the aspect ratio of central street is not excessively high, higher values of street continuity ratio and spatial closure ratio

  4. Role of the IL-12/IL-35 balance in patients with Sjögren syndrome.

    Science.gov (United States)

    Fogel, Olivier; Rivière, Elodie; Seror, Raphaèle; Nocturne, Gaetane; Boudaoud, Saida; Ly, Bineta; Gottenberg, Jacques-Eric; Le Guern, Véronique; Dubost, Jean-Jacques; Nititham, Joanne; Taylor, Kimberly E; Chanson, Philippe; Dieudé, Philippe; Criswell, Lindsey A; Jagla, Bernd; Thai, Alice; Mingueneau, Michael; Mariette, Xavier; Miceli-Richard, Corinne

    2017-09-12

    An interferon signature is involved in the pathogenesis of primary Sjögren syndrome (pSS), but whether the signature is type 1 or type 2 remains controversial. Mouse models and genetic studies suggest the involvement of T H 1 and type 2 interferon pathways. Likewise, polymorphisms of the IL-12A gene (IL12A), which encodes for IL-12p35, have been associated with pSS. The IL-12p35 subunit is shared by 2 heterodimers: IL-12 and IL-35. We sought to confirm genetic association of the IL12A polymorphism and pSS and elucidate involvement of the IL-12/IL-35 balance in patients with pSS by using functional studies. The genetic study involved 673 patients with pSS from 2 French pSS cohorts and 585 healthy French control subjects. Functional studies were performed on sorted monocytes, irrespective of whether they were stimulated. IL12A mRNA expression and IL-12 and IL-35 protein levels were assessed by using quantitative RT-PCR and ELISA and a multiplex kit for IL-35 and IL-12, respectively. We confirmed association of the IL12A rs485497 polymorphism and pSS and found an increased serum protein level of IL-12p70 in patients with pSS carrying the risk allele (P = .016). Serum levels of IL-12p70 were greater in patients than control subjects (P = .0001), especially in patients with more active disease (P = .05); conversely, IL-35 levels were decreased in patients (P = .0001), especially in patients with more active disease (P = .05). In blood cellular subsets both IL12p35 and EBV-induced gene protein 3 (EBI3) mRNAs were detected only in B cells, with a trend toward a lower level among patients with pSS. Our findings emphasize involvement of the IL-12/IL-35 balance in the pathogenesis of pSS. Serum IL-35 levels were associated with low disease activity, in contrast with serum IL-12p70 levels, which were associated with more active disease. Copyright © 2017 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  5. IL-2 absorption affects IFN-gamma and IL-5, but not IL-4 producing memory T cells in double color cytokine ELISPOT assays.

    Science.gov (United States)

    Quast, Stefan; Zhang, Wenji; Shive, Carey; Kovalovski, Damian; Ott, Patrick A; Herzog, Bernhard A; Boehm, Bernhard O; Tary-Lehmann, Magdalena; Karulin, Alexey Y; Lehmann, Paul V

    2005-09-01

    Cytokine assays are gaining increasing importance for human immune monitoring because they reliably detect antigen-specific T cells in primary PBMC, even at low clonal sizes. Double color ELISPOT assays permit the simultaneous visualization of cells producing two different cytokines. Permitting the simultaneous assessment of type 1 and 2 immunity and due to the limited numbers of PBMC available from human study subjects, double color assays should be particularly attractive for clinical trials. Since the performance of double color assays has not yet been validated, we set out to compare them to single color measurements. Testing the recall antigen-induced cytokine response of PBMC, we found that double color assays regularly provided lower numbers of IFN-gamma and IL-5 spots than single color measurements when IL-2 detection was part of the double color assay. We showed that the inhibitory effect resulted from IL-2 absorption and could be overcome by either antibody free preactivation cultures or by inclusion of anti-CD28 antibody. In contrast, the simultaneous detection of IL-2 did not affect the numbers of IL-4 spots. Therefore, unlike IL-2/IL-4 and IFN-gamma/IL-5 assays, IL-2/IFN-gamma, and IL-2/IL-5 assays require compensation for the IL-2 capture to provide accurate numbers for the frequencies of cytokine producing memory T cells.

  6. Clinical significance of determination of semen plasma IL-2, IL-6, IL-8 and TNF-α contents in infertile males

    International Nuclear Information System (INIS)

    Sun Baoyi; Li Jun; Zhang Jiyun

    2004-01-01

    Objective: To explore the influence of high semen plasma contents of the cytokines (IL-2, IL-6, IL-8, TNF-α) on male fertility. Methods: Semen plasma levels of IL-2, IL-6, IL-8, and TNF-α were determined with RIA in 126 infertile and 20 fertile males. Results: Semen plasma contents of the 4 cytokines in infertile subjects were significantly higher than those in fertile ones (p 4/HP, n=15) had significantly higher contents of cytokines than those without leucocytospermia (WBC<4/HP, n=111). Besides, TNF-α contents in subjects with lower sperm activity and less motility rate as well as IL-8 contents in subjects with less sperm motility rate were both significantly higher than those in subjects with more normal sperms (p<0.01, p<0.05). Conclusion: High semen plasma cytokines contents represent existing local infection and enhanced auto-immune status, both damaging to sperms. Infertility would be the inevitable consequence. Monitoring of changes of the cytokine contents should be a part of fertility studies

  7. Neglected populations: safeguarding the health of street-involved children in Ghana.

    Science.gov (United States)

    Osei-Twum, Jo-Ann; Wasan, Kishor M

    2012-10-01

    Ensuring the health of street-involved children is a growing public health challenge. These children are vulnerable, neglected, and rarely a priority for basic service providers and governments. Sizable populations of street-involved children are present in major urban areas worldwide and current trends in urbanization suggest these populations will grow in the coming years. Although migration offers employment and training opportunities, the health and wellbeing of children is negatively impacted by their interactions with the streets. However, systemic barriers may also prevent these children from achieving an adequate health status. The situation of street-involved children in Ghana, West Africa will be discussed. Copyright © 2012 Wiley Periodicals, Inc.

  8. Becoming a uCity: The Case of Chicago

    Directory of Open Access Journals (Sweden)

    Zorica Nedovic-Budic

    Full Text Available ABSTRACT: The concept of a ubiquitous city, or uCity, is gaining attention worldwide. In a uCity, anyone is enabled by information and communication technologies (ICT to do anything, anywhere, at any time. The uCity concept has spread more quickly than its implementation, which relies on a complex set of interrelated technologies, practices, and actors, including but not limited to the provision of ICT infrastructure, the availability and accessibility of information and services, and the adoption of mobile communication devices by a variety of users. To aid in measuring and implementing a uCity, we explore ways to measure the “ubiquity” of a city, with particular attention given to the first “A” above – i.e., “anyone”. Empirical findings from Chicago highlight: 1 ICT access, 2 the connectivity of institutions and individuals, and 3 the ubiquity of virtuality. A socio-technical perspective and social network and social capital theories guide this study. The underlying social and motivational processes are essential to all aspects of becoming a uCity. KEYWORDS: Ubiquitous city, urban planning, community informatics, Chicago

  9. Theoretical high energy physics research at the University of Chicago

    International Nuclear Information System (INIS)

    Rosner, J.L.; Martinec, E.J.; Sachs, R.G.

    1989-12-01

    This report contains brief discussions on theoretical High Energy Physics research done by the researchers at University of Chicago. Some topics covered are: lepton production; kaon decay; Higgs boson production; electric dipole moment of the neutron; string models; supersymmetry; and cosmic ray shower

  10. 76 FR 35106 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2011-06-16

    ...-AA00 Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago..., DHS. ACTION: Final rule. SUMMARY: The Coast Guard is establishing a permanent safety zone from Brandon... Safety Zones; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary...

  11. Increased IL-20 and IL-24 target osteoblasts and synovial monocytes in spondyloarthritis

    DEFF Research Database (Denmark)

    Kragstrup, Tue Wenzel; Andersen, Morten Nørgaard; Schiøttz-Christensen, Berit

    2017-01-01

    The pathogenesis of spondyloarthritis (SpA) involves activation of the innate immune system, inflammation and new bone formation. The two cytokines interleukin (IL)-20 and IL-24 have been shown to link innate immune activation and tissue homeostasis. We hypothesized that these two cytokines...... are secreted as part of activation of the innate immune system and affect bone homeostasis in SpA. IL-20 and IL-24 were measured in plasma from axial SpA patients (n = 83). Peripheral SpA patients (n = 16) were included for in-vitro cell culture studies. The plasma IL-20 and IL-24 levels were increased in Sp...

  12. Importance-satisfaction analysis of street food sanitation and choice factor in Korea and Taiwan

    OpenAIRE

    Joo, Nami; Park, Sanghyun; Lee, Bohee; Yoon, Jiyoung

    2015-01-01

    BACKGROUND/OBJECTIVES The present study investigated Korean and Taiwan adults on the importance of and the satisfaction with street food sanitation and street food choice factor, in order to present management and improvement measures for street foods. SUBJECTS/METHODS The present study conducted a survey on 400 randomly chosen adults (200 Korean, 200 Taiwanese). General characteristics, eating habits, street food intake frequency, and preference by type of street food of respondents were che...

  13. Eve in the renegade city: elite Jewish women’s philanthropy in Chicago, 1890–1900

    OpenAIRE

    Farmer, Hannah

    2012-01-01

    This thesis examines the philanthropic organisations and projects with which elite Jewish women in Chicago were concerned during the years 1890–1900. It concentrates on the National Council of Jewish Women, which was founded by a group of Chicago women in 1893 after the Jewish Women’s Congress at the World’s Columbian Exposition. The NCJW was this community’s highest-profile philanthropic organisation, bringing them local, national and international attention.The 1890s were a turbulent decade...

  14. Effect of stable stratification on dispersion within urban street canyons: A large-eddy simulation

    Science.gov (United States)

    Li, Xian-Xiang; Britter, Rex; Norford, Leslie K.

    2016-11-01

    This study employs a validated large-eddy simulation (LES) code with high tempo-spatial resolution to investigate the effect of a stably stratified roughness sublayer (RSL) on scalar transport within an urban street canyon. The major effect of stable stratification on the flow and turbulence inside the street canyon is that the flow slows down in both streamwise and vertical directions, a stagnant area near the street level emerges, and the vertical transport of momentum is weakened. Consequently, the transfer of heat between the street canyon and overlying atmosphere also gets weaker. The pollutant emitted from the street level 'pools' within the lower street canyon, and more pollutant accumulates within the street canyon with increasing stability. Under stable stratification, the dominant mechanism for pollutant transport within the street canyon has changed from ejections (flow carries high-concentration pollutant upward) to unorganized motions (flow carries high-concentration pollutant downward), which is responsible for the much lower dispersion efficiency under stable stratifications.

  15. [Correlation of serum IL-16, IL-18 levels and immunoglobulins in children with asthma].

    Science.gov (United States)

    Xue, Yi-Nan; Zou, Xian-De; Wu, Jia-Ling

    2006-02-01

    This study examined the changes of serum levels of interleukin (IL)-16, IL-18 and immunoglobulins and the correlation of serum IL-16, IL-18 levels and immunoglobulins in children with asthma and aimed to explore the role of IL-16, IL-18 and immunoglobulins in the pathogenesis of asthma. Thirty-four children with asthma and 21 age and gender-matched healthy children were enrolled in this study. The levels of IL-16, IL-18 and immunoglobulin E (IgE) were determined using ELISA. Immunoglobulin G (IgG), immunoglobulin M (IgM) and immunoglobulin A (IgA) were detected by immunoturbidimetry. The levels of IL-16, IL-18 and IgE in patients with asthma at both acute attack and convalescence stages were significantly higher than those in healthy controls. An increased IgG and a decreased IgA levels were found in asthmatic patients at the acute attack stage. There was a positive correlation between the IL-16 and IL-18 levels at both acute attack and convalescence stages of asthma (r=0.70, P attack stage of asthma (r=0.624, P asthma. The immunologic imbalance exists in children with asthma at both acute attack and convalescence stages. Anti-allergic therapy should be administered through the acute attack to the convalescence stages of asthma.

  16. The Initiation of Homeless Youth into the Street Economy

    Science.gov (United States)

    Gwadz, Marya Viorst; Gostnell, Karla; Smolenski, Carol; Willis, Brian; Nish, David; Nolan, Theresa C.; Tharaken, Maya; Ritchie, Amanda S.

    2009-01-01

    Homeless youth (HY) who lack employment in the formal economy typically turn to the street economy (e.g., prostitution, drug selling) for survival. Guided by the theory of social control, the present paper explores factors influencing HY's initiation into the street economy. Eighty HY (ages 15-23) were recruited from four community-based…

  17. Hygiene practices among street food vendors in Tamale Metropolis ...

    African Journals Online (AJOL)

    The study noted that street food business in the Tamale Metropolis was women dominated (76%). Majority of vendors (78%) were aged 20-39 years. Public toilets (pit latrines) were accessible to all vending sites. Though high number of street food vendors had some form of formal education (66%) and knowledge of food ...

  18. Commensal bacteria and MAMPs are necessary for stress-induced increases in IL-1β and IL-18 but not IL-6, IL-10 or MCP-1.

    Directory of Open Access Journals (Sweden)

    Thomas Maslanik

    Full Text Available Regular interactions between commensal bacteria and the enteric mucosal immune environment are necessary for normal immunity. Alterations of the commensal bacterial communities or mucosal barrier can disrupt immune function. Chronic stress interferes with bacterial community structure (specifically, α-diversity and the integrity of the intestinal barrier. These interferences can contribute to chronic stress-induced increases in systemic IL-6 and TNF-α. Chronic stress, however, produces many physiological changes that could indirectly influence immune activity. In addition to IL-6 and TNF-α, exposure to acute stressors upregulates a plethora of inflammatory proteins, each having unique synthesis and release mechanisms. We therefore tested the hypothesis that acute stress-induced inflammatory protein responses are dependent on the commensal bacteria, and more specifically, lipopolysaccharide (LPS shed from Gram-negative intestinal commensal bacteria. We present evidence that both reducing commensal bacteria using antibiotics and neutralizing LPS using endotoxin inhibitor (EI attenuates increases in some (inflammasome dependent, IL-1 and IL-18, but not all (inflammasome independent, IL-6, IL-10, and MCP-1 inflammatory proteins in the blood of male F344 rats exposed to an acute tail shock stressor. Acute stress did not impact α- or β- diversity measured using 16S rRNA diversity analyses, but selectively reduced the relative abundance of Prevotella. These findings indicate that commensal bacteria contribute to acute stress-induced inflammatory protein responses, and support the presence of LPS-mediated signaling in stress-evoked cytokine and chemokine production. The selectivity of the commensal bacteria in stress-evoked IL-1β and IL-18 responses may implicate the inflammasome in this response.

  19. Influence of the IL-1Ra gene polymorphism on in vivo synthesis of IL-1Ra and IL-1beta after live yellow fever vaccination.

    Science.gov (United States)

    Hacker, U T; Erhardt, S; Tschöp, K; Jelinek, T; Endres, S

    2001-09-01

    The inflammatory response in infectious and autoimmune diseases is regulated by the balance between pro- and anti-inflammatory cytokines. The IL-1 complex contains polymorphic genes coding for IL-1alpha, IL-1beta and IL-1Ra. The IL-1Ra (variable number of tanden repeat) VNTR polymorphism has been shown to influence the capacity to produce IL-1beta and IL-1Ra after in vitro stimulation. Allele 2 of this polymorphism is associated with a number of inflammatory diseases. To determine the impact of the IL-1Ra polymorphism on in vivo human cytokine synthesis, we used a yellow fever vaccination model for the induction of cytokine synthesis in healthy volunteers. Two different yellow fever vaccines were used. After administration of the RKI vaccine (34 volunteers), plasma TNF-alpha concentration increased from 13.4 +/- 0.9 pg/ml to 23.3 +/- 1.1 pg/ml (P < 0.001), and plasma IL-1Ra concentration increased from 308 +/- 25 pg/ml to 1019 +/- 111 pg/ml (P < 0.001), on day 2. Using Stamaril vaccine, no increase in the plasma concentrations of either TNF-alpha or IL-1Ra could be detected (n = 17). Only the RKI vaccine induced TNF-alpha synthesis after in vitro stimulation of MNC. Carriers of allele 2 of the IL-1Ra polymorphism had increased baseline concentrations of IL-1Ra (350 +/- 32 pg/ml) compared with non-carriers (222 +/- 18 pg/ml, P < 0.001), and decreased concentrations of IL-1beta (0.9 +/- 0.2 pg/ml for carriers versus 2.8 +/- 0.7 pg/ml for non-carriers, P = 0.017). After yellow fever vaccination (RKI vaccine), no significant differences in the increase of IL-1Ra plasma levels were detected between carriers and non-carriers of allele 2 of the IL-1Ra gene polymorphism. This is the first study to examine the influence of this genetic polymorphism on in vivo-induced human IL-1beta and IL-1Ra synthesis. Baseline concentrations of IL-1Ra and IL-1beta were significantly influenced by the IL-1Ra polymorphism. No influence of the IL-1Ra polymorphism on the in vivo

  20. Self-Localization at Street Intersections.

    Science.gov (United States)

    Fusco, Giovanni; Shen, Huiying; Coughlan, James M

    2014-05-01

    There is growing interest among smartphone users in the ability to determine their precise location in their environment for a variety of applications related to wayfinding, travel and shopping. While GPS provides valuable self-localization estimates, its accuracy is limited to approximately 10 meters in most urban locations. This paper focuses on the self-localization needs of blind or visually impaired travelers, who are faced with the challenge of negotiating street intersections. These travelers need more precise self-localization to help them align themselves properly to crosswalks, signal lights and other features such as walk light pushbuttons. We demonstrate a novel computer vision-based localization approach that is tailored to the street intersection domain. Unlike most work on computer vision-based localization techniques, which typically assume the presence of detailed, high-quality 3D models of urban environments, our technique harnesses the availability of simple, ubiquitous satellite imagery (e.g., Google Maps) to create simple maps of each intersection. Not only does this technique scale naturally to the great majority of street intersections in urban areas, but it has the added advantage of incorporating the specific metric information that blind or visually impaired travelers need, namely, the locations of intersection features such as crosswalks. Key to our approach is the integration of IMU (inertial measurement unit) information with geometric information obtained from image panorama stitchings. Finally, we evaluate the localization performance of our algorithm on a dataset of intersection panoramas, demonstrating the feasibility of our approach.

  1. 78 FR 17099 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago...

    Science.gov (United States)

    2013-03-20

    ...-AA00 Safety Zone, Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago... the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago... Guard will enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including...

  2. 78 FR 65874 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2013-11-04

    ...-AA00 Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago... the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago... Guard will enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including...

  3. 78 FR 4071 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2013-01-18

    ...-AA00 Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago... the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago... Coast Guard will enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan...

  4. 75 FR 64673 - Safety Zone, Brandon Road Lock and, Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2010-10-20

    ... Zone, Brandon Road Lock and, Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and... Safety Zone, Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Ship and...: The Coast Guard will enforce Safety Zone, Brandon Road Lock and Dam to Lake Michigan including Des...

  5. 77 FR 65478 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago...

    Science.gov (United States)

    2012-10-29

    ...-AA00 Safety Zone, Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago... the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago... segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River...

  6. 75 FR 64147 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2010-10-19

    ... Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Ship and Sanitary Canal... . SUPPLEMENTARY INFORMATION: The Coast Guard will enforce Safety Zone, Brandon Road Lock and Dam to Lake Michigan...

  7. 77 FR 60044 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2012-10-02

    ...-AA00 Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago... the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago... segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River...

  8. Analysis of the Treatment of a Biological Weapon Spread through a Transportation Network

    Science.gov (United States)

    2014-03-27

    public. Most of the skepticism stems from religion, rare complications, and parent concerns over a refuted study suggesting vaccines can cause autism. In...CHI 40 CHICAGO, IL MDW 22 CHICAGO, IL ORD 44 CINCINNATI, OH CVG 52 CLEVELAND, OH CLE 59 CODY, WY COD 2 COLLEGE STATION, TX CLL 1 COLORADO...CDC 1 COLLEGE STATION, TX CLL 1 COLUMBIA, MO COU 1 CORDOVA, AK CDV 1 DAYTONA BEACH, FL DAB 1 DUBUQUE, IA DBQ 1 DURANGO, CO DRO 1 DUTCH HARBOR

  9. IL-15 deficient tax mice reveal a role for IL-1α in tumor immunity.

    Directory of Open Access Journals (Sweden)

    Daniel A Rauch

    Full Text Available IL-15 is recognized as a promising candidate for tumor immunotherapy and has been described as both a promoter of cancer and a promoter of anti-cancer immunity. IL-15 was discovered in cells transformed by HTLV-1, the etiologic agent of adult T cell leukemia/lymphoma (ATL and the human retrovirus that carries the Tax oncogene. We have developed the TAX-LUC mouse model of ATL in which Tax expression drives both malignant transformation and luciferase expression, enabling non-invasive imaging of tumorigenesis in real time. To identify the role of IL-15 in spontaneous development of lymphoma in vivo, an IL-15(-/- TAX-LUC strain was developed and examined. The absence of IL-15 resulted in aggressive tumor growth and accelerated mortality and demonstrated that IL-15 was not required for Tax-mediated lymphoma but was essential for anti-tumor immunity. Further analysis revealed a unique transcriptional profile in tumor cells that arise in the absence of IL-15 that included a significant increase in the expression of IL-1α and IL-1α-regulated cytokines. Moreover, anti-IL-1α antibodies and an IL-1 receptor antagonist (Anakinra were used to interrogate the potential of IL-1α targeted therapies in this model. Taken together, these findings identify IL-15 and IL-1α as therapeutic targets in lymphoma.

  10. Temporal, spatial and social patterens of self-organization within street sport

    DEFF Research Database (Denmark)

    Sand, Anne-Lene

    Due to an increased urbanization and digitalization self-organized practices are becoming a central way of doing sports among contemporary young people and adults in urban contexts. The aim of this presentation is to contribute with knowledge about what it means to be self-organized within street...... young people can re-define urban space themselves (Skelton and Valentine 2007). During a multi-sited fieldwork (Marcus 1995) I followed people in Denmark that value to be able to improvise in the way they organize their own street-sport practices through temporal, spatial and social practices. Street...... among young people and adults, in order to redefine and reconstruct future leisure organizations (Rojek 1995) and understand contemporary forms of street sport....

  11. The propagation of sound in narrow street canyons

    Science.gov (United States)

    Iu, K. K.; Li, K. M.

    2002-08-01

    This paper addresses an important problem of predicting sound propagation in narrow street canyons with width less than 10 m, which are commonly found in a built-up urban district. Major noise sources are, for example, air conditioners installed on building facades and powered mechanical equipment for repair and construction work. Interference effects due to multiple reflections from building facades and ground surfaces are important contributions in these complex environments. Although the studies of sound transmission in urban areas can be traced back to as early as the 1960s, the resulting mathematical and numerical models are still unable to predict sound fields accurately in city streets. This is understandable because sound propagation in city streets involves many intriguing phenomena such as reflections and scattering at the building facades, diffusion effects due to recessions and protrusions of building surfaces, geometric spreading, and atmospheric absorption. This paper describes the development of a numerical model for the prediction of sound fields in city streets. To simplify the problem, a typical city street is represented by two parallel reflecting walls and a flat impedance ground. The numerical model is based on a simple ray theory that takes account of multiple reflections from the building facades. The sound fields due to the point source and its images are summed coherently such that mutual interference effects between contributing rays can be included in the analysis. Indoor experiments are conducted in an anechoic chamber. Experimental data are compared with theoretical predictions to establish the validity and usefulness of this simple model. Outdoor experimental measurements have also been conducted to further validate the model. copyright 2002 Acoustical Society of America.

  12. [Street food among children: a study in north Tunisia].

    Science.gov (United States)

    Neffati, Larbi; Ridha, Hamza; Kolsteren, Patrick; Hilderbrand, Katherine

    2004-01-01

    As urbanization increases in Tunisia, eating meals outside the home is becoming more frequent. Children are prime consumers for the fast food sold in the streets. Neither their nor their parents' attitude towards street food is well documented as yet. This study was conducted in the city of Bizerte in February 1998. Its aim was to gather information about street food and parents' and children's attitudes towards it to help organize educational sessions with the children, parents, teachers, and vendors. The study interviewed 421 primary school children, ranging in age from 6 to 15 years (mean age: 10 years), from 24 schools. Half received pocket money, a percentage that did not differ by sex. Three quarters of the children used more than 75% of their pocket money to buy street food. The items bought most frequently were candy (27.2%), sandwiches (23.9%), pastries (23.9%), sunflower seeds and peanuts (21%), and either pizza, chocolate, or cheese (20.3%); the largest proportion of money was spent on sandwiches. In more than half the cases (55.7% of the children), the main motivation for buying street food was either to replace or fill out a meal at home, with sandwiches or pastries. The parents' monthly income did not influence the children's purchasing behavior, but the rhythm of receiving pocket money did. Most children were satisfied with the nutritional and hygienic quality of the food available, but their opinion of this quality as well as the reasons for buying the food and the prices spent on it differed considerably from that of their parents. This study highlights the important role of street foods in the daily diet of schoolchildren and the need for appropriate nutrition education in primary schools.

  13. Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons ?

    Directory of Open Access Journals (Sweden)

    Heiko eMühl

    2013-02-01

    Full Text Available Interleukin (IL-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of transcription (STAT-3 as dominant signaling mode. IL-10, formerly known as cytokine synthesis inhibitory factor, is key to deactivation of monocytes/macrophages and dendritic cells. Accordingly, pre-clinical studies document its anti-inflammatory capacity. However, the outcome of clinical trials assessing the therapeutic potential of IL-10 in prototypic inflammatory disorders has been disappointing. In contrast to IL-10, IL-22 acts primarily on non-leukocytic cells, in particular epithelial cells of intestine, skin, liver, and lung. STAT3-driven proliferation, anti-apoptosis, and anti-microbial tissue protection is regarded a principal function of IL-22 at host/environment interfaces. In this hypothesis article, hidden/underappreciated pro-inflammatory characteristics of IL-10 and IL-22 are outlined and related to cellular priming by type I interferon. It is tempting to speculate that an inherent inflammatory potential of IL-10 and IL-22 confines their usage in tissue protective therapy and beyond that determines in some patients efficacy of type I interferon treatment.

  14. Expression of IL-8, IL-6 and IL-1β in Tears as a Main Characteristic of the Immune Response in Human Microbial Keratitis

    Science.gov (United States)

    Santacruz, Concepcion; Linares, Marisela; Garfias, Yonathan; Loustaunau, Luisa M.; Pavon, Lenin; Perez-Tapia, Sonia Mayra; Jimenez-Martinez, Maria C.

    2015-01-01

    Corneal infections are frequent and potentially vision-threatening diseases, and despite the significance of the immunological response in animal models of microbial keratitis (MK), it remains unclear in humans. The aim of this study was to describe the cytokine profile of tears in patients with MK. Characteristics of ocular lesions such as size of the epithelial defect, stromal infiltration, and hypopyon were analyzed. Immunological evaluation included determination of interleukine (IL)-1β, IL-6, IL-8, IL-10, IL-12 and tumor necrosis factor (TNF)-α in tear samples obtained from infected eyes of 28 patients with MK and compared with their contralateral non-infected eyes. Additionally, frequency of CD4+, CD8+, CD19+ and CD3−CD56+ cells was also determined in peripheral blood mononuclear cells in patients with MK, and compared with 48 healthy controls. Non-significant differences were observed in the size of the epithelial defect, stromal infiltration, and hypopyon. Nevertheless, we found an immunological profile apparently related to MK etiology. IL-8 > IL-6 in patients with bacterial keratitis; IL-8 > IL-6 > IL-1β and increased frequency of circulating CD3−CD56+ NK cells in patients with gram-negative keratitis; and IL-8 = IL-6 > IL-1β in patients with fungal keratitis. Characterization of tear cytokines from patients with MK could aid our understanding of the immune pathophysiological mechanisms underlying corneal damage in humans. PMID:25741769

  15. IL-10 and IL-27 producing dendritic cells capable of enhancing IL-10 production of T cells are induced in oral tolerance.

    Science.gov (United States)

    Shiokawa, Aya; Tanabe, Kosuke; Tsuji, Noriko M; Sato, Ryuichiro; Hachimura, Satoshi

    2009-06-30

    Oral tolerance is a key feature of intestinal immunity, generating systemic tolerance to ingested antigens (Ag). Dendritic cells (DC) have been revealed as important immune regulators, however, the precise role of DC in oral tolerance induction remains unclear. We investigated the characteristics of DC in spleen, mesenteric lymph node (MLN), and Peyer's patch (PP) after oral Ag administration in a TCR-transgenic mouse model. DC from PP and MLN of tolerized mice induced IL-10 production but not Foxp3 expression in cocultured T cells. IL-10 production was markedly increased after 5-7-day Ag administration especially in PP DC. On the other hand, IL-27 production was increased after 2-5-day Ag administration. CD11b(+) DC, which increased after ingestion of Ag, prominently expressed IL-10 and IL-27 compared with CD11b(-) DC. These results suggest that IL-10 and IL-27 producing DC are increased by interaction with antigen specific T cells in PP, and these DC act as an inducer of IL-10 producing T cells in oral tolerance.

  16. IL-7 Induces an Epitope Masking of γc Protein in IL-7 Receptor Signaling Complex

    Directory of Open Access Journals (Sweden)

    Tae Sik Goh

    2017-01-01

    Full Text Available IL-7 signaling via IL-7Rα and common γ-chain (γc is necessary for the development and homeostasis of T cells. Although the delicate mechanism in which IL-7Rα downregulation allows the homeostasis of T cell with limited IL-7 has been well known, the exact mechanism behind the interaction between IL-7Rα and γc in the absence or presence of IL-7 remains unclear. Additionally, we are still uncertain as to how only IL-7Rα is separately downregulated by the binding of IL-7 from the IL-7Rα/γc complex. We demonstrate here that 4G3, TUGm2, and 3E12 epitope masking of γc protein are induced in the presence of IL-7, indicating that the epitope alteration is induced by IL-7 binding to the preassembled receptor core. Moreover, the epitope masking of γc protein is inversely correlated with the expression of IL-7Rα upon IL-7 binding, implying that the structural alteration of γc might be involved in the regulation of IL-7Rα expression. The conformational change in γc upon IL-7 binding may contribute not only to forming the functional IL-7 signaling complex but also to optimally regulating the expression of IL-7Rα.

  17. IL-7 Induces an Epitope Masking of γc Protein in IL-7 Receptor Signaling Complex

    Science.gov (United States)

    Goh, Tae Sik; Jo, Yuna; Lee, Byunghyuk; Kim, Geona; Hwang, Hyunju; Ko, Eunhee; Kang, Seung Wan; Oh, Sae-Ock; Baek, Sun-Yong; Yoon, Sik; Lee, Jung Sub

    2017-01-01

    IL-7 signaling via IL-7Rα and common γ-chain (γc) is necessary for the development and homeostasis of T cells. Although the delicate mechanism in which IL-7Rα downregulation allows the homeostasis of T cell with limited IL-7 has been well known, the exact mechanism behind the interaction between IL-7Rα and γc in the absence or presence of IL-7 remains unclear. Additionally, we are still uncertain as to how only IL-7Rα is separately downregulated by the binding of IL-7 from the IL-7Rα/γc complex. We demonstrate here that 4G3, TUGm2, and 3E12 epitope masking of γc protein are induced in the presence of IL-7, indicating that the epitope alteration is induced by IL-7 binding to the preassembled receptor core. Moreover, the epitope masking of γc protein is inversely correlated with the expression of IL-7Rα upon IL-7 binding, implying that the structural alteration of γc might be involved in the regulation of IL-7Rα expression. The conformational change in γc upon IL-7 binding may contribute not only to forming the functional IL-7 signaling complex but also to optimally regulating the expression of IL-7Rα. PMID:28127156

  18. What information do Karman streets offer to flow sensing?

    Energy Technology Data Exchange (ETDEWEB)

    Akanyeti, Otar; Venturelli, Roberto; Visentin, Francesco; Fiorini, Paolo [Department of Computer Science, University of Verona, 37134 Verona (Italy); Chambers, Lily; Megill, William M, E-mail: otarakanyeti@yahoo.com [Department of Mechanical Engineering, University of Bath, Bath BA2 7AY (United Kingdom)

    2011-09-15

    In this work, we focus on biomimetic lateral line sensing in Karman vortex streets. After generating a Karman street in a controlled environment, we examine the hydrodynamic images obtained with digital particle image velocimetry (DPIV). On the grounds that positioning in the flow and interaction with the vortices govern bio-inspired underwater locomotion, we inspect the fluid in the swimming robot frame of reference. We spatially subsample the flow field obtained using DPIV to emulate the local flow around the body. In particular, we look at various sensor configurations in order to reliably identify the vortex shedding frequency, wake wavelength and downstream flow speed. Moreover, we propose methods that differentiate between being in and out of the Karman street with >70% accuracy, distinguish right from left with respect to Karman vortex street centreline (>80%) and highlight when the sensor system enters the vortex formation zone (>75%). Finally, we present a method that estimates the relative position of a sensor array with respect to the vortex formation point within 15% error margin.

  19. Characteristic, Emotional, and Behavioral Problems of Street Adolescent in Bandung October–December 2012

    Directory of Open Access Journals (Sweden)

    Annisa Nurfitriani

    2015-06-01

    Full Text Available Background: Street adolescents were psychosocial problem that increased in number each year and was worsened by their low-moral subculture-value that could cause them more vulnerable in having emotional and behavioral problems. This study aims to describe the characteristics, emotional and behavioral problems of the street adolescent in Bandung. Methods: A descriptive study was carried out in October–December 2012. From 22 shelters in Bandung, two shelters (RPA GANK and Pesantren Kolong Nurul Hayat were selected and organized into 4 areas: Cihampelas, ‘Samsat’, Laswi Street and Kiaracondong. A hundred-seven street adolescents aged 11 to 16 years were participated in this study. They were divided into small groups and filled in the sociodemographic questionnaire and the Indonesian version of standardized Strength and Difficulty Questionnaires (SDQ. Only 100 questionnaires were filled in completely. Data were analyzed using frequency tabulation and bar chart Results: Sixty-five percent were boys, 53% were aged 11–13 years, and 53% were students, 76% related to more than one sibling, still lived with their families (81%, and had parents. Their parents had low educational background, had job, and implemented authoritative parenting pattern (41%. In becoming street adolescent, 63% were caused by their own motivation, 81% were children on street, and 55% had lived in the street more than 5 years. Approximately 27% of street adolescents were rated as abnormal on the total difficulty score. Conclusion: Street adolescent in Bandung still have emotional and behavioral problems, which mostly were boys, in the early adolescence stage, school student, had more than one sibling, permissive parenting pattern, and lived in the street for more than 5 years.

  20. 76 FR 78161 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2011-12-16

    ... Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal... INFORMATION: The Coast Guard will enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake...

  1. 77 FR 20295 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago...

    Science.gov (United States)

    2012-04-04

    ... Zone, Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal... enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines...

  2. 75 FR 73966 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2010-11-30

    ... Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal... enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines...

  3. 77 FR 35854 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2012-06-15

    ... Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal... enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines...

  4. 78 FR 40635 - Safety Zone; Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2013-07-08

    ... Zone; Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal... Coast Guard will enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan...

  5. 78 FR 36092 - Safety Zone; Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2013-06-17

    ... Zone; Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal... Coast Guard will enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan...

  6. 76 FR 2829 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2011-01-18

    ... Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal... enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines...

  7. 75 FR 52462 - Safety Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago...

    Science.gov (United States)

    2010-08-26

    ... Zone, Brandon Road Lock and Dam to Lake Michigan Including Des Plaines River, Chicago Sanitary and Ship...; Brandon Road Lock and Dam to Lake Michigan including Des Plaines River, Chicago Sanitary and Ship Canal... enforce a segment of the Safety Zone; Brandon Road Lock and Dam to Lake Michigan including Des Plaines...

  8. Importance-satisfaction analysis of street food sanitation and choice factor in Korea and Taiwan.

    Science.gov (United States)

    Joo, Nami; Park, Sanghyun; Lee, Bohee; Yoon, Jiyoung

    2015-06-01

    The present study investigated Korean and Taiwan adults on the importance of and the satisfaction with street food sanitation and street food choice factor, in order to present management and improvement measures for street foods. The present study conducted a survey on 400 randomly chosen adults (200 Korean, 200 Taiwanese). General characteristics, eating habits, street food intake frequency, and preference by type of street food of respondents were checked. Respondents' importance and satisfaction of street food hygiene and selection attributes were also measured. In order to test for the difference between groups, χ(2)-test and t-test were performed. ISA was also performed to analyze importance and satisfaction. Results showed that the importance of sanitation was significantly higher than satisfaction on all items in both Korea and Taiwan, and the satisfaction with sanitation was higher in Taiwan than in Korea. According to ISA results with street food sanitation, satisfaction was low while importance was high in both Korea and Taiwan. In terms of street food choice factor, importance scores were significantly higher than satisfaction scores on all items. In addition, satisfaction scores on all items except 'taste' were significantly higher in Taiwan than in Korea. A manual on sanitation management of street foods should be developed to change the knowledge and attitude toward sanitation by putting into practice a regularly conducted education. Considering the popularity of street foods and its potential as a tourism resource to easily publicize our food culture, thorough management measures should be prepared on sanitation so that safe street food culture should be created.

  9. Virtual street-crossing performance in persons with multiple sclerosis: Feasibility and task performance characteristics.

    Science.gov (United States)

    Stratton, M E; Pilutti, L A; Crowell, J A; Kaczmarski, H; Motl, R W

    2017-01-02

    Multiple sclerosis (MS) is a neurological disease that commonly results in physical and cognitive dysfunction. Accordingly, MS might impact the ability to safely cross the street. The purpose of this study was to examine the feasibility of a simulated street-crossing task in persons with MS and to determine differences in street-crossing performance between persons with MS and non-MS controls. 26 participants with MS (median Expanded Disability Status Scale [EDSS] score = 3.5) and 19 controls completed 40 trials of a virtual street-crossing task. There were 2 crossing conditions (i.e., no distraction and phone conversation), and participants performed 20 trials per condition. Participants were instructed that the goal of the task was to cross the street successfully (i.e., without being hit be a vehicle). The primary outcome was task feasibility, assessed as completion and adverse events. Secondary outcomes were measures of street-crossing performance. Overall, the simulated street-crossing task was feasible (i.e., 90% completion, no adverse events) in participants with MS. Participants with MS waited longer and were less attentive to traffic before entering the street compared with controls (all P .05). A virtual street-crossing task is feasible for studying street-crossing behavior in persons with mild MS and most individuals with moderate MS. Virtual street-crossing performance is impaired in persons with MS compared to controls; however, persons with MS do not appear to be more vulnerable to a distracting condition. The virtual reality environment presents a safe and useful setting for understanding pedestrian behavior in persons with MS.

  10. Effect of asymmetrical street canyons on pedestrian thermal comfort in warm-humid climate of Cuba

    Science.gov (United States)

    Rodríguez-Algeciras, José; Tablada, Abel; Matzarakis, Andreas

    2017-07-01

    Walkability and livability in cities can be enhanced by creating comfortable environments in the streets. The profile of an urban street canyon has a substantial impact on outdoor thermal conditions at pedestrian level. This paper deals with the effect of asymmetrical street canyon profiles, common in the historical centre of Camagüey, Cuba, on outdoor thermal comfort. Temporal-spatial analyses are conducted using the Heliodon2 and the RayMan model, which enable the generation of accurate predictions about solar radiation and thermal conditions of urban spaces, respectively. On these models, urban settings are represented by asymmetrical street canyons with five different height-to-width ratios and four street axis orientations (N-S, NE-SW, E-W, SE-NW). Results are evaluated for daytime hours across the street canyon, by means of the physiologically equivalent temperature (PET index) which allows the evaluation of the bioclimatic conditions of outdoor environments. Our findings revealed that high profiles (façades) located on the east-facing side of N-S streets, on the southeast-facing side of NE-SW streets, on the south-facing side of E-W street, and on the southwest-facing side of SE-NW streets, are recommended to reduce the total number of hours under thermal stress. E-W street canyons are the most thermally stressed ones, with extreme PET values around 36 °C. Deviating from this orientation ameliorates the heat stress with reductions of up to 4 h in summer. For all analysed E-W orientations, only about one fifth of the street can be comfortable, especially for high aspect ratios (H/W > 3). Optimal subzones in the street are next to the north side of the E-W street, northwest side of the NE-SW street, and southwest side of the SE-NW street. Besides, when the highest profile is located on the east side of N-S streets, then the subzone next to the east-facing façade is recommendable for pedestrians. The proposed urban guidelines enable urban planners to create

  11. What caused Chicago bank failures in the Great Depression? A look at the 1920s.

    OpenAIRE

    Natacha Postel-Vinay

    2015-01-01

    This paper reassesses the causes of Chicago bank failures during the Great Depression by tracking the evolution of their balance sheets in the 1920s. I find that all Chicago banks suffered tremendous deposit withdrawals; however banks that failed earlier in the 1930s had invested more in mortgages in the 1920s. The main problem with mortgages was their lack of liquidity, not their quality. Banks heavily engaged in mortgages did not have enough liquid assets to face the withdrawals and failed....

  12. Study of locations’characteristics for stabilization of street vendors in Surakarta City

    Science.gov (United States)

    Rahayu, M. J.; Buchori, I.; Widjajanti, R.

    2018-01-01

    Street vendors are usually centered around particular areas where they have made adaptations based on their activities, instead of scattered all over the city. These locations tend to be close to street vendors’ primary activities and consumers, occupy the public lands, and are productive and accessible. The Municipality of Surakarta has managed the street vendors in the form of stabilization and relocation. In Surakarta, there are 24 areas used for stabilization of street vendors varying in characteristics and quantities. This study uses a spatial analysis aiming to explain the characteristics of locations used for stabilization of street vendors and to identify their physical condition and arrangement. Furthermore, all of the research results will be used as the criteria in choosing the new locations that are suitable for the street vendors’ characteristics and consumers’ preference. The results show that the locations are on the roadsides of the neighborhood, local, and secondary collector roads. The traffic conditions in the stabilization areas are ranging from the very busy until relatively busy level since they are close to activities for trade, education, recreation, offices, and settlements.

  13. IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival.

    Science.gov (United States)

    Webster, K E; Kim, H-O; Kyparissoudis, K; Corpuz, T M; Pinget, G V; Uldrich, A P; Brink, R; Belz, G T; Cho, J-H; Godfrey, D I; Sprent, J

    2014-09-01

    Natural killer T (NKT) cells are innate-like T cells that rapidly recognize pathogens and produce cytokines that shape the ensuing immune response. IL-17-producing NKT cells are enriched in barrier tissues, such as the lung, skin, and peripheral lymph nodes, and the factors that maintain this population in the periphery have not been elucidated. Here we show that NKT17 cells deviate from other NKT cells in their survival requirements. In contrast to conventional NKT cells that are maintained by IL-15, RORγt(+) NKT cells are IL-15 independent and instead rely completely on IL-7. IL-7 initiates a T-cell receptor-independent (TCR-independent) expansion of NKT17 cells, thus supporting their homeostasis. Without IL-7, survival is dramatically impaired, yet residual cells remain lineage committed with no downregulation of RORγt evident. Their preferential response to IL-7 does not reflect enhanced signaling through STAT proteins, but instead is modulated via the PI3K/AKT/mTOR signaling pathway. The ability to compete for IL-7 is dependent on high-density IL-7 receptor expression, which would promote uptake of low levels of IL-7 produced in the non-lymphoid sites of lung and skin. This dependence on IL-7 is also reported for RORγt(+) innate lymphoid cells and CD4(+) Th17 cells, and suggests common survival requirements for functionally similar cells.

  14. Concentrations of polycyclic aromatic hydrocarbons and inorganic constituents in ambient surface soils, Chicago, Illinois: 2001-2002

    Science.gov (United States)

    Kay, R.T.; Arnold, T.L.; Cannon, W.F.; Graham, D.

    2008-01-01

    Samples of ambient surface soils were collected from 56 locations in Chicago, Illinois, using stratified random sampling techniques and analyzed for polycyclic aromatic hydrocarbon (PAH) compounds and inorganic constituents. PAHs appear to be derived primarily from combustion of fossil fuels and may be affected by proximity to industrial operations, but do not appear to be substantially affected by the organic carbon content of the soil, proximity to nonindustrial land uses, or proximity to a roadway. Atmospheric settling of particulate matter appears to be an important mechanism for the placement of PAH compounds into soils. Concentrations of most inorganic constituents are affected primarily by soil-forming processes. Concentrations of lead, arsenic, mercury, calcium, magnesium, phosphorus, copper, molybdenum, zinc, and selenium are elevated in ambient surface soils in Chicago in comparison to the surrounding area, indicating anthropogenic sources for these elements in Chicago soils. Concentrations of calcium and magnesium in Chicago soils appear to reflect the influence of the carbonate bedrock parent material on the chemical composition of the soil, although the effects of concrete and road fill cannot be discounted. Concentrations of inorganic constituents appear to be largely unaffected by the type of nearby land use. Copyright ?? Taylor & Francis Group, LLC.

  15. Psychiatric Disorders and Substance Use in Homeless Youth: A Preliminary Comparison of San Francisco and Chicago

    Directory of Open Access Journals (Sweden)

    Ernika G. Quimby

    2012-08-01

    Full Text Available Youth homelessness is a growing problem in the United States. The experience of homelessness appears to have numerous adverse consequences, including psychiatric and substance use disorders. This study compared the frequencies of psychiatric disorders, including substance use, between homeless youth (18–24 years-old in San Francisco (N = 31 and Chicago (N = 56. Subjects were administered the Mini International Neuropsychiatric Interview (M.I.N.I. to assess DSM-IV-TR diagnoses and substance use disorders. Eighty-seven percent of the San Francisco youth, and 81% of the Chicago youth met criteria for at least one M.I.N.I. psychiatric diagnosis. Nearly two-thirds of the youth in both samples met criteria for a mood disorder. Approximately one-third met criteria for an anxiety disorder. Thirty-two percent of the San Francisco sample and 18% of the Chicago met criteria for Antisocial Personality Disorder. Approximately 84% of the San Francisco youth and 48% of the Chicago youth met criteria for a substance-related disorder, and more substances were used by San Francisco youth. In conclusion, the high rate of psychiatric disorders in homeless youth provides clear evidence that the mental health needs of this population are significant. Implications are discussed.

  16. Bacterial contamination of street vending food in Kumasi, Ghana ...

    African Journals Online (AJOL)

    Street vending foods are readily available sources of meals for many people but the biological safe-ty of such food is always in doubt. The aim of this study is to ascertain bacterial isolate and deter-mine total counts of bacterial species responsible for the contamination of the street vending food in Kumasi so as to determine ...

  17. INTRODUCTION The term street children has many definitions in ...

    African Journals Online (AJOL)

    this, the still schooling street children in this study may likely have gravitated to the streets due to the lack of recreational facilities to keep youths occupied after school hours in the rural areas. As at the time of study, no amusement parks, cinemas and other recreational places exists in the Local Government Area. It is known.

  18. India : Energy-Efficient Street Lighting--Implementation and Financing Solutions

    OpenAIRE

    World Bank

    2015-01-01

    There has been a clear need for energy-efficient (EE) technologies that can be applicable in the municipal street lighting sector. The objective of this manual is to support the preparation and implementation of street lighting projects in India, using performance contracting and other public private partnership-based delivery approaches. This manual draws upon global best practices, inclu...

  19. Drug Use among Street Children in Tehran, Iran: A Qualitative Study

    Directory of Open Access Journals (Sweden)

    Masoumeh eDejman

    2015-12-01

    Full Text Available Introduction and objective: Globally, children who work and live on the streets are at higher risk of undesired behavioral health outcomes, including increased drug use and abuse. Considering the rapid growth of this population in Iran and the lack of program planning that is partly due to a scarcity of research-based information, this study was conducted in 2013 to investigate drug use among street children in Tehran. Method: With a qualitative design, we conducted a Rapid Assessment and Response (RAS Survey of street children in Tehran, 2012-2013. Data were also obtained from ten focus group discussions with street children using semi-structured questionnaires and 27 in-depth interviews with key informants in governmental, non-governmental, and international organizations. Results: The variation in age at first use, type of drugs, and pattern of drug use were found based on ethnicity. Gypsy boys and girls reported consuming more alcohol than other groups. Drug use problems were commonly described among families of street children. Children whose parents had drug-use problems described using drugs earlier than other children. Informants reported that families with drug-related problems used children for procurement of drugs. Children themselves described using drugs to cope with stress, reduce physical and psychological stressors and problems such as fatigue, sadness, and pressure resulting from frequent failures in life. Conclusion: These results suggest that intervention and prevention programs dealing with drug use of street children in Iran should include family and peers when addressing drug use by street children.

  20. OpenStreetMap Collaborative Prototype, Phase 1

    Science.gov (United States)

    Wolf, Eric B.; Matthews, Greg D.; McNinch, Kevin; Poore, Barbara S.

    2011-01-01

    Phase One of the OpenStreetMap Collaborative Prototype (OSMCP) attempts to determine if the open source software developed for the OpenStreetMap (OSM, http://www.openstreetmap.org) can be used for data contributions and improvements that meet or exceed the requirements for integration into The National Map (http://www.nationalmap.gov). OpenStreetMap Collaborative Prototype Phase One focused on road data aggregated at the state level by the Kansas Data Access and Support Center (DASC). Road data from the DASC were loaded into a system hosted by the U.S. Geological Survey (USGS) National Geospatial Technical Operations Center (NGTOC) in Rolla, Missouri. U.S. Geological Survey editing specifications were developed by NGTOC personnel (J. Walters and G. Matthews, USGS, unpub. report, 2010). Interstate and U.S. Highways in the dataset were edited to the specifications by NGTOC personnel while State roads were edited by DASC personnel. Resulting data were successfully improved to meet standards for The National Map once the system and specifications were in place. The OSM software proved effective in providing a usable platform for collaborative data editing