A NEW ARTIFICIAL DIFFUSION FACTOR IN THE STREAMLINE UPWIND/PETROV GALERKIN FORMULATION
无
2002-01-01
For the incompressible Navier-Stokes equa-tions, a new artificial diffusion factor is put forward in theStreamline Upwind/Petrov Galerkin formulation. The corre-sponding formulae of finite element methods are derived inNewton-Raphson form, in which velocity and pressure are it-erated synchronously. An element with nine nodes satisfyinginf-sup condition is established, which has a parabolic velocityinterpolation and linear pressure distribution. Four numericalexamples are presented, and solutions obtained demonstratethe effectivity of the method proposed.
Jagtap, Ameya Dilip
2015-01-01
A novel explicit and implicit Kinetic Streamlined-Upwind Petrov Galerkin (KSUPG) scheme is presented for hyperbolic equations such as Burgers equation and compressible Euler equations. The proposed scheme performs better than the original SUPG stabilized method in multi-dimensions. To demonstrate the numerical accuracy of the scheme, various numerical experiments have been carried out for 1D and 2D Burgers equation as well as for 1D and 2D Euler equations using Q4 and T3 elements. Furthermore, spectral stability analysis is done for the explicit 2D formulation. Finally, a comparison is made between explicit and implicit versions of the KSUPG scheme.
Carlos Humberto Galeano Urueña
2010-05-01
Full Text Available This article describes the streamline upwind Petrov-Galerkin (SUPG method as being a stabilisation technique for resolving the diffusion-advection-reaction equation by finite elements. The first part of this article has a short analysis of the importance of this type of differential equation in modelling physical phenomena in multiple fields. A one-dimensional description of the SUPG me- thod is then given to extend this basis to two and three dimensions. The outcome of a strongly advective and a high numerical complexity experiment is presented. The results show how the version of the implemented SUPG technique allowed stabilised approaches in space, even for high Peclet numbers. Additional graphs of the numerical experiments presented here can be downloaded from www.gnum.unal.edu.co.
Petrov-Galerkin Spectral Element Method for Mixed Inhomogeneous Boundary Value Problems on Polygons
Hongli JIA; Benyu GUO
2010-01-01
The authors investigate Petrov-Galerkin spectral element method.Some results on Legendre irrational quasi-orthogonal approximations are established,which play important roles in Petrov-Galerkin spectral element method for mixed inhomogeneous boundary value problems of partial differential equations defined on polygons.As examples of applications,spectral element methods for two model problems,with the spectral accuracy in certain Jacobi weighted Sobolev spaces,are proposed.The techniques developed in this paper are also applicable to other higher order methods.
Global Error Bounds for the Petrov-Galerkin Discretization of the Neutron Transport Equation
Chang, B; Brown, P; Greenbaum, A; Machorro, E
2005-01-21
In this paper, we prove that the numerical solution of the mono-directional neutron transport equation by the Petrov-Galerkin method converges to the true solution in the L{sup 2} norm at the rate of h{sup 2}. Since consistency has been shown elsewhere, the focus here is on stability. We prove that the system of Petrov-Galerkin equations is stable by showing that the 2-norm of the inverse of the matrix for the system of equations is bounded by a number that is independent of the order of the matrix. This bound is equal to the length of the longest path that it takes a neutron to cross the domain in a straight line. A consequence of this bound is that the global error of the Petrov-Galerkin approximation is of the same order of h as the local truncation error. We use this result to explain the widely held observation that the solution of the Petrov-Galerkin method is second accurate for one class of problems, but is only first order accurate for another class of problems.
Yang Xiu-Li; Dai Bao-Dong; Zhang Wei-Wei
2012-01-01
Based on the complex variable moving least-square (CVMLS) approximation and a local symmetric weak form,the complex variable meshless local Petrov-Galerkin (CVMLPG) method of solving two-dimensional potential problems is presented in this paper.In the present formulation,the trial function of a two-dimensional problem is formed with a one-dimensional basis function.The number of unknown coefficients in the trial function of the CVMLS approximation is less than that in the trial function of the moving least-square (MLS) approximation.The essential boundary conditions are imposed by the penalty method.The main advantage of this approach over the conventional meshless local PetrovGalerkin (MLPG) method is its computational efficiency.Several numerical examples are presented to illustrate the implementation and performance of the present CVMLPG method.
Streamline upwind finite element method for conjugate heat transfer problems
Niphon Wansophark; Atipong Malatip; Pramote Dechaumphai; Yunming Chen
2005-01-01
This paper presents a combined finite element method for solving conjugate heat transfer problems where heat conduction in a solid is coupled with heat convection in viscous fluid flow. The streamline upwind finite element method is used for the analysis of thermal viscous flow in the fluid region, whereas the analysis of heat conduction in solid region is performed by the Galerkin method. The method uses the three-node triangular element with equal-order interpolation functions for all the variables of the velocity components,the pressure and the temperature. The main advantage of the proposed method is to consistently couple heat transfer along the fluid-solid interface. Three test cases, i.e. conjugate Couette flow problem in parallel plate channel, counter-flow in heat exchanger, and conjugate natural convection in a square cavity with a conducting wall, are selected to evaluate the efficiency of the present method.
Mejía De Alba, Manuel Felipe
2011-01-01
El presente trabajo analiza y compara los problemas numéricos derivados al modelar problemas altamente convectivos empleando diversos métodos espectrales y el método Streamline Petrov-Galerkin de elementos finitos (SUPG). El análisis comparativo de las gráficas de convergencia para diferentes números de Peclet, mostraron la superioridad de los métodos espectrales sobre las técnicas convencionales usadas para tratar problemas de advección dominante: elementos finitos SUPG y diferen...
Diego Alexander Garzón Alvarado
2009-01-01
Full Text Available El presente artículo estudia el método Streamline Upwind Petrov Galerkin como técnica de estabilización de la solución numérica de las ecuaciones diferenciales de advección-difusión-reacción; se analiza el método a la luz de la naturaleza no auto adjunta del operador diferencial convectivo y de las transformaciones necesarias para la estabilización de la solución por medio de la eliminación del efecto no autoadjunto inducido por el término convectivo. Se desarrollaron seis diversos ejemplos numéricos, los cuales incluyen problemas de coeficientes variables, altamente convectivos, fuertemente reactivos, sistemas de ecuaciones diferenciales y soluciones transitorias. Se encuentra un excelente desempeño de esta técnica de estabilización para todos los casos anteriormente mencionados, exceptuando los problemas con términos reactivos fuertes.
A Jacobi Dual-Petrov-Galerkin Method for Solving Some Odd-Order Ordinary Differential Equations
E. H. Doha
2011-01-01
Full Text Available A Jacobi dual-Petrov-Galerkin (JDPG method is introduced and used for solving fully integrated reformulations of third- and fifth-order ordinary differential equations (ODEs with constant coefficients. The reformulated equation for the Jth order ODE involves n-fold indefinite integrals for n=1,…,J. Extension of the JDPG for ODEs with polynomial coefficients is treated using the Jacobi-Gauss-Lobatto quadrature. Numerical results with comparisons are given to confirm the reliability of the proposed method for some constant and polynomial coefficients ODEs.
A MESHLESS LOCAL PETROV-GALERKIN METHOD FOR GEOMETRICALLY NONLINEAR PROBLEMS
Xiong Yuanbo; Long Shuyao; Hu De'an; Li Guangyao
2005-01-01
Nonlinear formulations of the meshless local Petrov-Galerkin (MLPG) method are presented for geometrically nonlinear problems. The method requires no mesh in computation and therefore avoids mesh distortion difficulties in the large deformation analysis. The essential boundary conditions in the present formulation are imposed by a penalty method. An incremental and iterative solution procedure is used to solve geometrically nonlinear problems. Several examples are presented to demonstrate the effectiveness of the method in geometrically nonlinear problems analysis. Numerical results show that the MLPG method is an effective one and that the values of the unknown variable are quite accurate.
Roberts, Nathan V.; Demkowiz, Leszek; Moser, Robert
2015-11-15
The discontinuous Petrov-Galerkin methodology with optimal test functions (DPG) of Demkowicz and Gopalakrishnan [18, 20] guarantees the optimality of the solution in an energy norm, and provides several features facilitating adaptive schemes. Whereas Bubnov-Galerkin methods use identical trial and test spaces, Petrov-Galerkin methods allow these function spaces to differ. In DPG, test functions are computed on the fly and are chosen to realize the supremum in the inf-sup condition; the method is equivalent to a minimum residual method. For well-posed problems with sufficiently regular solutions, DPG can be shown to converge at optimal rates—the inf-sup constants governing the convergence are mesh-independent, and of the same order as those governing the continuous problem [48]. DPG also provides an accurate mechanism for measuring the error, and this can be used to drive adaptive mesh refinements. We employ DPG to solve the steady incompressible Navier-Stokes equations in two dimensions, building on previous work on the Stokes equations, and focusing particularly on the usefulness of the approach for automatic adaptivity starting from a coarse mesh. We apply our approach to a manufactured solution due to Kovasznay as well as the lid-driven cavity flow, backward-facing step, and flow past a cylinder problems.
NUMERICAL ANALYSIS OF MINDLIN SHELL BY MESHLESS LOCAL PETROV-GALERKIN METHOD
Di Li; Zhongqin Lin; Shuhui Li
2008-01-01
The objectives of this study are to employ the meshless local Petrov-Galerkin method (MLPGM) to solve three-dimensional shell problems. The computational accuracy of MLPGM for shell problems is affected by many factors, including the dimension of compact support domain, the dimension of quadrture domain, the number of integral cells and the number of Gauss points. These factors' sensitivity analysis is to adopt the Taguchi experimental design technology and point out the dimension of the quadrature domain with the largest influence on the computational accuracy of the present MLPGM for shells and give out the optimum combination of these factors. A few examples are given to verify the reliability and good convergence of MLPGM for shell problems compared to the theoretical or the finite element results.
A complex variable meshless local Petrov-Galerkin method for transient heat conduction problems
Wang Qi-Fang; Dai Bao-Dong; Li Zhen-Feng
2013-01-01
On the basis of the complex variable moving least-square (CVMLS) approximation,a complex variable meshless local Petrov-Galerkin (CVMLPG) method is presented for transient heat conduction problems.The method is developed based on the CVMLS approximation for constructing shape functions at scattered points,and the Heaviside step function is used as a test function in each sub-domain to avoid the need for a domain integral in symmetric weak form.In the construction of the well-performed shape function,the trial function of a two-dimensional (2D) problem is formed with a one-dimensional (1 D) basis function,thus improving computational efficiency.The numerical results are compared with the exact solutions of the problems and the finite element method (FEM).This comparison illustrates the accuracy as well as the capability of the CVMLPG method.
Sladek, J.; Sladek, V.; Zhang, Ch.
2008-02-01
A meshless local Petrov-Galerkin (MLPG) formulation is presented for analysis of shear deformable shallow shells with orthotropic material properties and continuously varying material properties through the shell thickness. Shear deformation of shells described by the Reissner theory is considered. Analyses of shells under static and dynamic loads are given here. For transient elastodynamic case the Laplace-transform is used to eliminate the time dependence of the field variables. A weak formulation with a unit test function transforms the set of the governing equations into local integral equations on local subdomains in the plane domain of the shell. The meshless approximation based on the Moving Least-Squares (MLS) method is employed for the implementation.
Bernstein dual-Petrov-Galerkin method: application to 2D time fractional diffusion equation
Jani, Mostafa; Babolian, Esmail
2016-01-01
In this paper, we develop a dual-Petrov-Galerkin method using Bernstein polynomials. The method is then implemented for the numerical simulation of the two-dimensional subdiffusion equation. The method is based on a finite difference discretization in time and a spectral method in space utilizing a suitable compact combinations of dual Bernstein basis as the test functions and the Bernstein polynomials as the trial ones. We derive the exact sparse operational matrix of differentiation for the dual Bernstein basis which provides a matrix-based approach for spatial discretization of the problem. It is also shown that the proposed method leads to banded linear systems. Finally some numerical examples are provided to show the efficiency and accuracy of the method.
Shu-hua Zhang; Tao Lin; Yan-ping Lin; Ming Rao
2001-01-01
In this paper we will show that the Richardson extrapolation can be used to enhance the numerical solution generated by a Petrov-Galerkin finite element method for the initialvalue problem for a nonlinear Volterra integro-differential equation. As by-products, we will also show that these enhanced approximations can be used to form a class of aposteriori estimators for this Petrov-Galerkin finite element method. Numerical examples are supplied to illustrate the theoretical results.
L. Jones Tarcius Doss
2012-01-01
Full Text Available A quadrature-based mixed Petrov-Galerkin finite element method is applied to a fourth-order linear ordinary differential equation. After employing a splitting technique, a cubic spline trial space and a piecewise linear test space are considered in the method. The integrals are then replaced by the Gauss quadrature rule in the formulation itself. Optimal order a priori error estimates are obtained without any restriction on the mesh.
Meshless Local Discontinuous Petrov-Galerkin Method with Application to Blasting Problems
QIANG Hongfu; GAO Weiran
2008-01-01
A meshless local discontinuous Petrov-Galerkin (MLDPG)method based on the local symmetric weak form(LSWF)is presented with the application to blasting problems.The derivation is similar to that of mesh-based Runge-Kutta Discontinuous Galerkin(RKDG)method.The solutions are reproduced in a set of overlapped spherical sub-domains.and the test functions are employed from a partition of unlty of the lpeal basis functions.There is no need of any traditional nonoverlapping mesh either for lpeal approximation purpose or for Galerkin integration purpose in the presented method.The resulting MLDPG method is a meshless.stable.high-order accurate and highly parallelizable scheme which inherits both the advantages of RKDG and meshless method (MM),and it can handle the problems with extremely complicated physics and geometries easily.Three numerical exampies of the one-dimensional Sod shock-tube problem.the blast-wave problem and the Woodward-Cpiella interacting shock wave problem are given.All the numerical results are in good agreement with the closed solutions.The higher-order MLDPG schemes can reproduce more accurate solution than the lower-order schemes.
Petrov-Galerkin Method for the Coupled Schrödinger-KdV Equation
M. S. Ismail
2014-01-01
Full Text Available Petrov-Galerkin method is used to derive a numerical scheme for the coupled Schrödinger-KdV (SKdV equations, where we have used the cubic B-splines as a test functions and a linear B-splines as a trial functions. Product approximation technique is used to deal with the nonlinear terms. An implicit midpoint rule and the Runge-Kutta method of fourth-order (RK4 are used to discretize in time. A block nonlinear pentadiagonal system is obtained. We solve this system by the fixed point method. The resulting scheme has a fourth-order accuracy in space direction and second-order in time direction in case of the implicit midpoint rule and it is unconditionally stable by von Neumann method. Using the RK4 method the scheme will be linear and fourth-order in time and space directions, and it is also conditionally stable. The exact soliton solution and the conserved quantities are used to assess the accuracy and to show the robustness and the efficiency of the proposed schemes.
A Jacobi Dual-Petrov Galerkin-Jacobi Collocation Method for Solving Korteweg-de Vries Equations
Bhrawy, Ali H.; Al-Shomrani, M. M.
2012-01-01
The present paper is devoted to the development of a new scheme to solve the initial-boundary value Korteweg-de Vries equation which models many physical phenomena such as surface water waves in a channel. The scheme consists of Jacobi dual-Petrov Galerkin-Jacobi collocation method in space combined with Crank-Nicholson-leap-frog method in time such that at each time step only a sparse banded linear algebraic system needs to be solved. Numerical results are presented to show that the proposed...
Niemi, Antti H.
2011-05-14
We revisit the finite element analysis of convection dominated flow problems within the recently developed Discontinuous Petrov-Galerkin (DPG) variational framework. We demonstrate how test function spaces that guarantee numerical stability can be computed automatically with respect to the so called optimal test space norm by using an element subgrid discretization. This should make the DPG method not only stable but also robust, that is, uniformly stable with respect to the Ṕeclet number in the current application. The e_ectiveness of the algorithm is demonstrated on two problems for the linear advection-di_usion equation.
Niemi, Antti H.
2013-12-01
We investigate the application of the discontinuous Petrov-Galerkin (DPG) finite element framework to stationary convection-diffusion problems. In particular, we demonstrate how the quasi-optimal test space norm improves the robustness of the DPG method with respect to vanishing diffusion. We numerically compare coarse-mesh accuracy of the approximation when using the quasi-optimal norm, the standard norm, and the weighted norm. Our results show that the quasi-optimal norm leads to more accurate results on three benchmark problems in two spatial dimensions. We address the problems associated to the resolution of the optimal test functions with respect to the quasi-optimal norm by studying their convergence numerically. In order to facilitate understanding of the method, we also include a detailed explanation of the methodology from the algorithmic point of view. © 2013 Elsevier Ltd. All rights reserved.
Niemi, Antti
2013-05-01
We revisit the finite element analysis of convection-dominated flow problems within the recently developed Discontinuous Petrov-Galerkin (DPG) variational framework. We demonstrate how test function spaces that guarantee numerical stability can be computed automatically with respect to the optimal test space norm. This makes the DPG method not only stable but also robust, that is, uniformly stable with respect to the Péclet number in the current application. We employ discontinuous piecewise Bernstein polynomials as trial functions and construct a subgrid discretization that accounts for the singular perturbation character of the problem to resolve the corresponding optimal test functions. We also show that a smooth B-spline basis has certain computational advantages in the subgrid discretization. The overall effectiveness of the algorithm is demonstrated on two problems for the linear advection-diffusion equation. © 2011 Elsevier B.V.
Calo, Victor M.
2014-01-01
We analyze the discontinuous Petrov-Galerkin (DPG) method with optimal test functions when applied to solve the Reissner-Mindlin model of plate bending. We prove that the hybrid variational formulation underlying the DPG method is well-posed (stable) with a thickness-dependent constant in a norm encompassing the L2-norms of the bending moment, the shear force, the transverse deflection and the rotation vector. We then construct a numerical solution scheme based on quadrilateral scalar and vector finite elements of degree p. We show that for affine meshes the discretization inherits the stability of the continuous formulation provided that the optimal test functions are approximated by polynomials of degree p+3. We prove a theoretical error estimate in terms of the mesh size h and polynomial degree p and demonstrate numerical convergence on affine as well as non-affine mesh sequences. © 2013 Elsevier Ltd. All rights reserved.
Carlberg, Kevin
2010-10-28
A Petrov-Galerkin projection method is proposed for reducing the dimension of a discrete non-linear static or dynamic computational model in view of enabling its processing in real time. The right reduced-order basis is chosen to be invariant and is constructed using the Proper Orthogonal Decomposition method. The left reduced-order basis is selected to minimize the two-norm of the residual arising at each Newton iteration. Thus, this basis is iteration-dependent, enables capturing of non-linearities, and leads to the globally convergent Gauss-Newton method. To avoid the significant computational cost of assembling the reduced-order operators, the residual and action of the Jacobian on the right reduced-order basis are each approximated by the product of an invariant, large-scale matrix, and an iteration-dependent, smaller one. The invariant matrix is computed using a data compression procedure that meets proposed consistency requirements. The iteration-dependent matrix is computed to enable the least-squares reconstruction of some entries of the approximated quantities. The results obtained for the solution of a turbulent flow problem and several non-linear structural dynamics problems highlight the merit of the proposed consistency requirements. They also demonstrate the potential of this method to significantly reduce the computational cost associated with high-dimensional non-linear models while retaining their accuracy. © 2010 John Wiley & Sons, Ltd.
Ansari, R.; Arjangpay, A.
2014-09-01
The meshless local Petrov-Galerkin (MLPG) method is implemented to analyze the free vibration and axial buckling characteristics of single-walled carbon nanotubes (SWCNTs) with different boundary conditions. To this end, a nonlocal shell model accounting for the small scale effect is used. In the theoretical formulations, a variational form of the Donnell shell equations is constructed over a local sub-domain which leads to derivation of the mass, stiffness and geometrical stiffness matrices. Comprehensive results for the resonant frequencies and critical axial buckling loads of SWCNTs are presented. The influences of boundary conditions, nonlocal parameter and geometrical parameters on the mechanical behavior of SWCNTs are fully investigated. The results obtained from the present numerical scheme are shown to be in good agreement with those from exact solution for simply-supported SWCNTs and those of molecular dynamics simulations. It is shown that the natural frequencies and critical axial buckling loads of SWCNTs are strongly dependent on the small scale effect and geometrical parameters.
Niphon Wansophark; Pramote Dechaumphai
2008-01-01
A streamline upwind finite element method using 6-node triangular element is presented.The method is applied to the convection term of the governing transport equation directly along local streamlines.Several convective-diffusion examples are used to evaluate efficiency of the method.Results show that the method is monotonic and does not produce any oscillation.In addition,an adaptive meshing technique is combined with the method to further increase accuracy of the solution,and at the same time,to minimize computational time and computer memory requirement.
Doha, E H; Abd-Elhameed, W M; Youssri, Y H
2015-09-01
Two families of certain nonsymmetric generalized Jacobi polynomials with negative integer indexes are employed for solving third- and fifth-order two point boundary value problems governed by homogeneous and nonhomogeneous boundary conditions using a dual Petrov-Galerkin method. The idea behind our method is to use trial functions satisfying the underlying boundary conditions of the differential equations and the test functions satisfying the dual boundary conditions. The resulting linear systems from the application of our method are specially structured and they can be efficiently inverted. The use of generalized Jacobi polynomials simplify the theoretical and numerical analysis of the method and also leads to accurate and efficient numerical algorithms. The presented numerical results indicate that the proposed numerical algorithms are reliable and very efficient.
Merton, S. R.; Smedley-Stevenson, R. P. [Computational Physics Group, AWE Aldermaston, Reading, Berkshire RG7 4PR (United Kingdom); Pain, C. C. [Dept. of Earth Science and Engineering, Imperial College London, London SW7 2AZ (United Kingdom)
2012-07-01
This paper describes a Non-Linear Discontinuous Petrov-Galerkin method and its application to the one-speed Boltzmann Transport Equation (BTE) for space-time problems. The purpose of the method is to remove unwanted oscillations in the transport solution which occur in the vicinity of sharp flux gradients, while improving computational efficiency and numerical accuracy. This is achieved by applying artificial dissipation in the solution gradient direction, internal to an element using a novel finite element (FE) Riemann approach. The added dissipation is calculated at each node of the finite element mesh based on local behaviour of the transport solution on both the spatial and temporal axes of the problem. Thus a different dissipation is used in different elements. The magnitude of dissipation that is used is obtained from a gradient-informed scaling of the advection velocities in the stabilisation term. This makes the method in its most general form non-linear. The method is implemented within a very general finite element Riemann framework. This makes it completely independent of choice of angular basis function allowing one to use different descriptions of the angular variation. Results show the non-linear scheme performs consistently well in demanding time-dependent multi-dimensional neutron transport problems. (authors)
Zitelli, J.
2011-04-01
The phase error, or the pollution effect in the finite element solution of wave propagation problems, is a well known phenomenon that must be confronted when solving problems in the high-frequency range. This paper presents a new method with no phase errors for one-dimensional (1D) time-harmonic wave propagation problems using new ideas that hold promise for the multidimensional case. The method is constructed within the framework of the discontinuous Petrov-Galerkin (DPG) method with optimal test functions. We have previously shown that such methods select solutions that are the best possible approximations in an energy norm dual to any selected test space norm. In this paper, we advance by asking what is the optimal test space norm that achieves error reduction in a given energy norm. This is answered in the specific case of the Helmholtz equation with L2-norm as the energy norm. We obtain uniform stability with respect to the wave number. We illustrate the method with a number of 1D numerical experiments, using discontinuous piecewise polynomial hp spaces for the trial space and its corresponding optimal test functions computed approximately and locally. A 1D theoretical stability analysis is also developed. © 2010 Elsevier Inc.
DIEGO GARZÓN
2010-01-01
Full Text Available El presente artículo analiza la estabilidad espacial y temporal de una solución numérica de la ecuación de difusiónadvección, a través del método de PetrovGalerkin en contracorriente (SUPG, junto con una discretización temporal BackwardEuler. En la primera parte del artículo se plantean los conceptos fundamentales de la técnica de estabilización espacial SUPG para dos dimensiones y posteriormente se presentan las consideraciones empleadas para la discretización temporal. A continuación se trata la metodología y las expresiones necesarias para la implementación computacional del método. Se analizan dos casos de estudio en los cuales se compara la estabilidad espacial y temporal de la solución implementada, con la obtenida por medio de la aproximación convencional BubnovGalerkin. Se emplea el error en norma de energía para analizar la estabilidad de las aproximaciones obtenidas. Videos y gráficas adicionales de los problemas presentados en este artículo pueden ser descargados de www.gnum.unal.edu.co
A Numerical Development in the Dynamical Equations of Solitons in Optical Fibers
Érica Regina Takano Natti
2006-02-01
Full Text Available It was evaluated the numerical resolution of a nonlinear differential equations system that describes the solitons propagation in dielectric optical fibers, through the method of finite elements, which is implemented based on Streamline Upwind Petrov-Galerkin (SUPG and Consistent Approximate Upwind (CAU formulations.
NUMERICAL ANALYSIS OF A FEM FOR A TRANSIENT VISCOELASTIC FLOW
穆君; 冯民富
2004-01-01
We present the numerical analysis of a coupled method for the numerical simulation of transient viscoelastic flow obeying a differential constitutive equation with a Newtonian viscosity. The scheme used is based on Euler implicit method in time and maintains at each time step a couple of the velocity u and the viscoelastic part of the stress σ. Approximation in space is made by finite element method. The approximate stress, velocity and pressure are, respectively, P1-continuous, p2-continuous, and p1continuous. Upwinding needed for convection of σ is made by a "Streamline Upwind Petrov Galerkin" method (SUPG).
Cheng HUANG; Dai ZHOU; Yan BAO
2011-01-01
A numerical algorithm using a bilinear or linear finite element and semi-implicit three-step method is presented for the analysis of incompressible viscous fluid problems. The streamline upwind/Petrov-Galerkin (SUPG) stabilization scheme is used for the formulation of the Navier-Stokes equations. For the spatial discretization, the convection term is treated explicitly, while the viscous term is treated implicitly, and for the temporal discretization, a three-step method is employed. The present method is applied to simulate the lid driven cavity problems with different geometries at low and high Reynolds numbers. The results compared with other numerical experiments are found to be feasible and satisfactory.
Le Hardy, D.; Favennec, Y.; Rousseau, B.
2016-08-01
The 2D radiative transfer equation coupled with specular reflection boundary conditions is solved using finite element schemes. Both Discontinuous Galerkin and Streamline-Upwind Petrov-Galerkin variational formulations are fully developed. These two schemes are validated step-by-step for all involved operators (transport, scattering, reflection) using analytical formulations. Numerical comparisons of the two schemes, in terms of convergence rate, reveal that the quadratic SUPG scheme proves efficient for solving such problems. This comparison constitutes the main issue of the paper. Moreover, the solution process is accelerated using block SOR-type iterative methods, for which the determination of the optimal parameter is found in a very cheap way.
Advanced numerical methods and software approaches for semiconductor device simulation
CAREY,GRAHAM F.; PARDHANANI,A.L.; BOVA,STEVEN W.
2000-03-23
In this article the authors concisely present several modern strategies that are applicable to drift-dominated carrier transport in higher-order deterministic models such as the drift-diffusion, hydrodynamic, and quantum hydrodynamic systems. The approaches include extensions of upwind and artificial dissipation schemes, generalization of the traditional Scharfetter-Gummel approach, Petrov-Galerkin and streamline-upwind Petrov Galerkin (SUPG), entropy variables, transformations, least-squares mixed methods and other stabilized Galerkin schemes such as Galerkin least squares and discontinuous Galerkin schemes. The treatment is representative rather than an exhaustive review and several schemes are mentioned only briefly with appropriate reference to the literature. Some of the methods have been applied to the semiconductor device problem while others are still in the early stages of development for this class of applications. They have included numerical examples from the recent research tests with some of the methods. A second aspect of the work deals with algorithms that employ unstructured grids in conjunction with adaptive refinement strategies. The full benefits of such approaches have not yet been developed in this application area and they emphasize the need for further work on analysis, data structures and software to support adaptivity. Finally, they briefly consider some aspects of software frameworks. These include dial-an-operator approaches such as that used in the industrial simulator PROPHET, and object-oriented software support such as those in the SANDIA National Laboratory framework SIERRA.
A variational multiscale method for particle-cloud tracking in turbomachinery flows
Corsini, A.; Rispoli, F.; Sheard, A. G.; Takizawa, K.; Tezduyar, T. E.; Venturini, P.
2014-11-01
We present a computational method for simulation of particle-laden flows in turbomachinery. The method is based on a stabilized finite element fluid mechanics formulation and a finite element particle-cloud tracking method. We focus on induced-draft fans used in process industries to extract exhaust gases in the form of a two-phase fluid with a dispersed solid phase. The particle-laden flow causes material wear on the fan blades, degrading their aerodynamic performance, and therefore accurate simulation of the flow would be essential in reliable computational turbomachinery analysis and design. The turbulent-flow nature of the problem is dealt with a Reynolds-Averaged Navier-Stokes model and Streamline-Upwind/Petrov-Galerkin/Pressure-Stabilizing/Petrov-Galerkin stabilization, the particle-cloud trajectories are calculated based on the flow field and closure models for the turbulence-particle interaction, and one-way dependence is assumed between the flow field and particle dynamics. We propose a closure model utilizing the scale separation feature of the variational multiscale method, and compare that to the closure utilizing the eddy viscosity model. We present computations for axial- and centrifugal-fan configurations, and compare the computed data to those obtained from experiments, analytical approaches, and other computational methods.
Corsini, A.; Rispoli, F.; Sheard, A. G.; Tezduyar, T. E.
2012-12-01
The paper illustrates how a computational fluid mechanic technique, based on stabilized finite element formulations, can be used in analysis of noise reduction devices in axial fans. Among the noise control alternatives, the study focuses on the use of end-plates fitted at the blade tips to control the leakage flow and the related aeroacoustic sources. The end-plate shape is configured to govern the momentum transfer to the swirling flow at the blade tip. This flow control mechanism has been found to have a positive link to the fan aeroacoustics. The complex physics of the swirling flow at the tip, developing under the influence of the end-plate, is governed by the rolling up of the jet-like leakage flow. The RANS modelling used in the computations is based on the streamline-upwind/Petrov-Galerkin and pressure-stabilizing/Petrov-Galerkin methods, supplemented with the DRDJ stabilization. Judicious determination of the stabilization parameters involved is also a part of our computational technique and is described for each component of the stabilized formulation. We describe the flow physics underlying the design of the noise control device and illustrate the aerodynamic performance. Then we investigate the numerical performance of the formulation by analysing the inner workings of the stabilization operators and of their interaction with the turbulence model.
Zhou, Hu; Wan, Decheng
2015-03-01
Although the upwind configuration is more popular in the field of wind energy, the downwind one is a promising type for the offshore wind energy due to its special advantages. Different configurations have different aerodynamic performance and it is important to predict the performance of both downwind and upwind configurations accurately for designing and developing more reliable wind turbines. In this paper, a numerical investigation on the aerodynamic performance of National Renewable Energy Laboratory (NREL) phase VI wind turbine in downwind and upwind configurations is presented. The open source toolbox OpenFOAM coupled with arbitrary mesh interface (AMI) method is applied to tackle rotating problems of wind turbines. Two 3D numerical models of NREL phase VI wind turbine with downwind and upwind configurations under four typical working conditions of incoming wind velocities are set up for the study of different unsteady characteristics of the downwind and upwind configurations, respectively. Numerical results of wake vortex structure, time histories of thrust, pressure distribution on the blade and limiting streamlines which can be used to identify points of separation in a 3D flow are presented. It can be concluded that thrust reduction due to blade-tower interaction is small for upwind wind turbines but relatively large for downwind wind turbines and attention should be paid to the vibration at a certain frequency induced by the cyclic reduction for both configurations. The results and conclusions are helpful to analyze the different aerodynamic performance of wind turbines between downwind and upwind configurations, providing useful references for practical design of wind turbine.
Hu Zhou; Decheng Wan
2015-01-01
Although the upwind configuration is more popular in the field of wind energy, the downwind one is a promising type for the offshore wind energy due to its special advantages. Different configurations have different aerodynamic performance and it is important to predict the performance of both downwind and upwind configurations accurately for designing and developing more reliable wind turbines. In this paper, a numerical investigation on the aerodynamic performance of National Renewable Energy Laboratory (NREL) phase VI wind turbine in downwind and upwind configurations is presented. The open source toolbox OpenFOAM coupled with arbitrary mesh interface (AMI) method is applied to tackle rotating problems of wind turbines. Two 3D numerical models of NREL phase VI wind turbine with downwind and upwind configurations under four typical working conditions of incoming wind velocities are set up for the study of different unsteady characteristics of the downwind and upwind configurations, respectively. Numerical results of wake vortex structure, time histories of thrust, pressure distribution on the blade and limiting streamlines which can be used to identify points of separation in a 3D flow are presented. It can be concluded that thrust reduction due to blade-tower interaction is small for upwind wind turbines but relatively large for downwind wind turbines and attention should be paid to the vibration at a certain frequency induced by the cyclic reduction for both configurations. The results and conclusions are helpful to analyze the different aerodynamic performance of wind turbines between downwind and upwind configurations, providing useful references for practical design of wind turbine.
Meshless Local Petrov-Galerkin Method for Solving Contact, Impact and Penetration Problems
2006-11-30
cylindrical rod is modeled as being elasto- plastic, and the material is chosen as AISI 310 steel with the following material constants: density: 8.027 g...H.G.; Atluri S.N. (2002): “Conducting cracks in dissimilar piezoelectric media” International Journal of Fracture, 118 (4): 285- 301 Beom H.G.; Atluri
Upwind dynamic soaring of albatrosses and UAVs
Richardson, Philip L.
2015-01-01
Albatrosses have been observed to soar in an upwind direction using what is called here an upwind mode of dynamic soaring. The upwind mode was modeled using the dynamics of a two-layer Rayleigh cycle in which the lower layer has zero velocity and the upper layer has a uniform wind speed of W. The upwind mode consists of a climb across the wind-shear layer headed upwind, a 90° turn and descent across the wind-shear layer perpendicular to the wind, followed by a 90° turn into the wind. The increase of airspeed gained from crossing the wind-shear layer headed upwind was balanced by the decrease of airspeed caused by drag. Results show that a wandering albatross can soar over the ocean in an upwind direction at a mean speed of 8.4 m/s in a 3.6 m/s wind, which is the minimum wind speed necessary for sustained dynamic soaring. A main result is that albatrosses can soar upwind much faster than the wind speed. Furthermore, albatrosses were found to be able to increase upwind speeds in winds greater than 3.6 m/s, reaching an upwind speed of 12.1 m/s in a wind speed of 7 m/s (for example). The upwind dynamic soaring mode of a possible robotic albatross UAV (Unmanned Aerial Vehicle) was modeled using a Rayleigh cycle and characteristics of a high-performance glider. Maximum possible airspeeds are equal to approximately 9.5 times the wind speed of the upper layer. In a wind of 10 m/s, the maximum possible upwind (56 m/s) and across-wind (61 m/s) components of UAV velocity over the ocean result in a diagonal upwind velocity of 83 m/s. In sufficient wind, a UAV could, in principle, use fast diagonal speeds to rapidly survey large areas of the ocean surface and the marine boundary layer. In practice, the maximum speeds of a UAV soaring over the ocean could be significantly less than these predictions. Some limitations to achieving fast travel velocities over the ocean are discussed and suggestions are made for further studies to test the concept of a robotic albatross.
Almeida, Regina Celia Cerqueira de
1993-12-31
A space-time finite element finite element formulation for the compressible Euler and Navier-Stokes equations is proposed. The present work develops a stable generalized CAU method which represents shocks and boundary-layers accurately. An h-adaptive remeshing refinement, which takes into account directional stretching and stretching ratio, is used leading to a very good way to indicate and refine the flow regions with singularities. Numerical experiment were conducted for some steady and unsteady problems and the performance of the proposed methods is discussed. (author) 63 refs., 40 figs.
Acquisition streamlining: A cultural change
Stewart, Jesse
1992-01-01
The topics are presented in viewgraph form and include the following: the defense systems management college, educational philosophy, the defense acquisition environment, streamlining initiatives, organizational streamlining types, defense law review, law review purpose, law review objectives, the Public Law Pilot Program, and cultural change.
UPWIND 1A2 Metrology. Final Report
Eecen, P.J.; Wagenaar, J.W.; Stefanatos, N.
The UpWind project is a European research project that focuses on the necessary up-scaling of wind energy in 2020. Among the problems that hinder the development of wind energy are measurement problems. For example: to experimentally confirm a theoretical improvement in energy production of a few...... percent of a new design by field experiments is very hard to almost impossible. As long as convincing field tests have not confirmed the actual improvement, the industry will not invest much to change the turbine design. This is an example that clarifies why the development of wind energy is hindered...... by metrology problems (measurement problems). Other examples are in the fields of: • Warranty performance measurements • Improvement of aerodynamic codes • Assessment of wind resources In general terms the uncertainties of the testing techniques and methods are typically much higher than the requirements...
Iterated upwind schemes for gas dynamics
Smolarkiewicz, Piotr K.; Szmelter, Joanna
2009-01-01
A class of high-resolution schemes established in integration of anelastic equations is extended to fully compressible flows, and documented for unsteady (and steady) problems through a span of Mach numbers from zero to supersonic. The schemes stem from iterated upwind technology of the multidimensional positive definite advection transport algorithm (MPDATA). The derived algorithms employ standard and modified forms of the equations of gas dynamics for conservation of mass, momentum and either total or internal energy as well as potential temperature. Numerical examples from elementary wave propagation, through computational aerodynamics benchmarks, to atmospheric small- and large-amplitude acoustics with intricate wave-flow interactions verify the approach for both structured and unstructured meshes, and demonstrate its flexibility and robustness.
Noise generation of upwind motor wind turbine generators
Spencer, R. H.
1981-01-01
Noise sources of wind turbines with rotors upstream of the support structure are discussed along with methodology for sound level prediction. Estimated noise levels for the MOD-2 wind turbine are presented operating in both the upwind and downwind configurations. Results indicate that upwind rotor configurations may be advantageous from an acoustical standpoint.
Regulatory Streamlining and Improvement
Mark A. Carl
2006-07-11
The Interstate Oil and Gas Compact Commission (IOGCC) engaged in numerous projects outlined under the scope of work discussed in the United States Department of Energy (DOE) grant number DE-FC26-04NT15456 awarded to the IOGCC. Numerous projects were completed that were extremely valuable to state oil and gas agencies as a result of work performed utilizing resources provided by the grant. There are numerous areas in which state agencies still need assistance. This additional assistance will need to be addressed under future scopes of work submitted annually to DOE's Project Officer for this grant. This report discusses the progress of the projects outlined under the grant scope of work for the 2005-2006 areas of interest, which are as follows: Area of Interest No. 1--Regulatory Streamlining and Improvement: This area of interest continues to support IOGCC's regulatory streamlining efforts that include the identification and elimination of unnecessary duplications of efforts between and among state and federal programs dealing with exploration and production on public lands. Area of Interest No. 2--Technology: This area of interest seeks to improve efficiency in states through the identification of technologies that can reduce costs. Area of Interest No. 3--Training and Education: This area of interest is vital to upgrading the skills of regulators and industry alike. Within the National Energy Policy, there are many appropriate training and education opportunities. Education was strongly endorsed by the President's National Energy Policy Development group. Acting through the governors offices, states are very effective conduits for the dissemination of energy education information. While the IOGCC favors the development of a comprehensive, long-term energy education plan, states are also supportive of immediate action on important concerns, such as energy prices, availability and conservation. Area of Interest No. 4--Resource Assessment and
Margot Gerritsen
2008-10-31
the redundant work generally done in the near-well regions. We improved the accuracy of the streamline simulator with a higher order mapping from pressure grid to streamlines that significantly reduces smoothing errors, and a Kriging algorithm is used to map from the streamlines to the background grid. The higher accuracy of the Kriging mapping means that it is not essential for grid blocks to be crossed by one or more streamlines. The higher accuracy comes at the price of increased computational costs, but allows coarser coverage and so does not generally increase the overall costs of the computations. To reduce errors associated with fixing the pressure field between pressure updates, we developed a higher order global time-stepping method that allows the use of larger global time steps. Third-order ENO schemes are suggested to propagate components along streamlines. Both in the two-phase and three-phase experiments these ENO schemes outperform other (higher order) upwind schemes. Application of the third order ENO scheme leads to overall computational savings because the computational grid used can be coarsened. Grid adaptivity along streamlines is implemented to allow sharp but efficient resolution of solution fronts at reduced computational costs when displacement fronts are sufficiently separated. A correction for Volume Change On Mixing (VCOM) is implemented that is very effective at handling this effect. Finally, a specialized gravity operator splitting method is proposed for use in compositional streamline methods that gives an effective correction of gravity segregation. A significant part of our effort went into the development of a parallelization strategy for streamline solvers on the next generation shared memory machines. We found in this work that the built-in dynamic scheduling strategies of OpenMP lead to parallel efficiencies that are comparable to optimal schedules obtained with customized explicit load balancing strategies as long as the ratio of
UPWIND DISCONTINUOUS GALERKIN METHODS FOR TWO DIMENSIONAL NEUTRON TRANSPORT EQUATIONS
袁光伟; 沈智军; 闫伟
2003-01-01
In this paper the upwind discontinuous Galerkin methods with triangle meshes for two dimensional neutron transport equations will be studied.The stability for both of the semi-discrete and full-discrete method will be proved.
The standard upwind compact difference schemes for incompressible flow simulations
Fan, Ping
2016-10-01
Compact difference schemes have been used extensively for solving the incompressible Navier-Stokes equations. However, the earlier formulations of the schemes are of central type (called central compact schemes, CCS), which are dispersive and susceptible to numerical instability. To enhance stability of CCS, the optimal upwind compact schemes (OUCS) are developed recently by adding high order dissipative terms to CCS. In this paper, it is found that OUCS are essentially not of the upwind type because they do not use upwind-biased but central type of stencils. Furthermore, OUCS are not the most optimal since orders of accuracy of OUCS are at least one order lower than the maximum achievable orders. New upwind compact schemes (called standard upwind compact schemes, SUCS) are developed in this paper. In contrast to OUCS, SUCS are constructed based completely on upwind-biased stencils and hence can gain adequate numerical dissipation with no need for introducing optimization calculations. Furthermore, SUCS can achieve the maximum achievable orders of accuracy and hence be more compact than OUCS. More importantly, SUCS have prominent advantages on combining the stable and high resolution properties which are demonstrated from the global spectral analyses and typical numerical experiments.
许星明; 赵国群; 秦升学; 王威
2011-01-01
The numerical simulation of extrudate swell is significant in extrusion processing. Precise prediction of extrudate swell is propitious to the control of melt flow and the quality of final products. A mathematical model of three-dimensional (3D) viscoelastic flow through elliptical ring die for polymer extrusion was investigated. The penalty function formulation of viscoelastic incompressible fluid was introduced to the finite element model to analyze 3D extrusion problem. The discrete elastic viscous split stress (DEVSS) and streamline-upwind PetrovGalerkin (SUPG) technology were used to obtain stable simulation results. Free surface was updated by updating the streamlines which needs less memory space. According to numerical simulation results, the effect of zero-shear viscosity and elongation parameter on extrudate swell was slight, but with the increase of volumetric flow rate and relax time the extrudate swell ratio increased markedly. Finally, the numerical simulation of extrudate swell flow for low-density polyethylene (LDPE) melts was investigated and the results agreed well with others' work. These conclusions provided quantitative basis for the forecasting extrudate swell ratio and the controlling of extrusion productivity shape.
Interactive Streamline Exploration and Manipulation Using Deformation
Tong, Xin; Chen, Chun-Ming; Shen, Han-Wei; Wong, Pak C.
2015-01-12
Occlusion presents a major challenge in visualizing three-dimensional flow fields with streamlines. Displaying too many streamlines at once makes it difficult to locate interesting regions, but displaying too few streamlines risks missing important features. A more ideal streamline exploration model is to allow the viewer to freely move across the field that has been populated with interesting streamlines and pull away the streamlines that cause occlusion so that the viewer can inspect the hidden ones in detail. In this paper, we present a streamline deformation algorithm that supports such user-driven interaction with three-dimensional flow fields. We define a view-dependent focus+context technique that moves the streamlines occluding the focus area using a novel displacement model. To preserve the context surrounding the user-chosen focus area, we propose two shape models to define the transition zone for the surrounding streamlines, and the displacement of the contextual streamlines is solved interactively with a goal of preserving their shapes as much as possible. Based on our deformation model, we design an interactive streamline exploration tool using a lens metaphor. Our system runs interactively so that users can move their focus and examine the flow field freely.
Margot Gerritsen
2008-10-31
the redundant work generally done in the near-well regions. We improved the accuracy of the streamline simulator with a higher order mapping from pressure grid to streamlines that significantly reduces smoothing errors, and a Kriging algorithm is used to map from the streamlines to the background grid. The higher accuracy of the Kriging mapping means that it is not essential for grid blocks to be crossed by one or more streamlines. The higher accuracy comes at the price of increased computational costs, but allows coarser coverage and so does not generally increase the overall costs of the computations. To reduce errors associated with fixing the pressure field between pressure updates, we developed a higher order global time-stepping method that allows the use of larger global time steps. Third-order ENO schemes are suggested to propagate components along streamlines. Both in the two-phase and three-phase experiments these ENO schemes outperform other (higher order) upwind schemes. Application of the third order ENO scheme leads to overall computational savings because the computational grid used can be coarsened. Grid adaptivity along streamlines is implemented to allow sharp but efficient resolution of solution fronts at reduced computational costs when displacement fronts are sufficiently separated. A correction for Volume Change On Mixing (VCOM) is implemented that is very effective at handling this effect. Finally, a specialized gravity operator splitting method is proposed for use in compositional streamline methods that gives an effective correction of gravity segregation. A significant part of our effort went into the development of a parallelization strategy for streamline solvers on the next generation shared memory machines. We found in this work that the built-in dynamic scheduling strategies of OpenMP lead to parallel efficiencies that are comparable to optimal schedules obtained with customized explicit load balancing strategies as long as the ratio of
Improvement of Mixing Function for Modified Upwinding Compact Scheme
Fu, Huankun; Liu, Chaoqun
2014-01-01
The compact scheme has high order accuracy and high resolution, but cannot be used to capture the shock. WENO is a great scheme for shock capturing, but is too dissipative for turbulence and small length scales. We developed a modified upwinding compact scheme which uses an effective shock detector to block compact scheme to cross the shock and a control function to mix the flux with WENO scheme near the shock. The new scheme makes the original compact scheme able to capture the shock sharply and, more important, keep high order accuracy and high resolution in the smooth area, which is particularly important for shock boundary layer and shock acoustic interactions. This work is a continuation to modify the control function for the modified up-winding compact scheme (MUCS). Numerical results show the scheme is successful for 2-D Euler.
In-flight measurement of upwind dynamic soaring in albatrosses
Sachs, Gottfried
2016-03-01
In-flight measurement results on upwind flight of albatrosses using dynamic soaring are presented. It is shown how the birds manage to make progress against the wind on the basis of small-scale dynamic soaring maneuvers. For this purpose, trajectory features, motion quantities and mechanical energy relationships as well as force characteristics are analyzed. The movement on a large-scale basis consists of a tacking type flight technique which is composed of dynamic soaring cycle sequences with alternating orientation to the left and right. It is shown how this is performed by the birds so that they can achieve a net upwind flight without a transversal large-scale movement and how this compares with downwind or across wind flight. Results on upwind dynamic soaring are presented for low and high wind speed cases. It is quantified how much the tacking trajectory length is increased when compared with the beeline distance. The presented results which are based on in-flight measurements of free flying albatrosses were achieved with an in-house developed GPS-signal tracking method yielding the required high precision for the small-scale dynamic soaring flight maneuvers.
Large eddy simulation for wind field analysis based on stabilized finite element method
Cheng HUANG; Yan BAO; Dai ZHOU; Jin-quan XU
2011-01-01
In this paper, a stabilized finite element technique, actualized by streamline upwind Petrov-Galerkin (SUPG) stabilized method and three-step finite element method (FEM), for large eddy simulation (LES) is developed to predict the wind flow with high Reynolds numbers. Weak form of LES motion equation is combined with the SUPG stabilized term for the spatial finite element discretization. An explicit three-step scheme is implemented for the temporal discretization. For the numerical example of 2D wind flow over a square rib at Re=4.2×105, the Smagorinsky's subgrid-scale (SSGS) model, the DSGS model, and the DSGS model with Cabot near-wall model are applied, and their results are analyzed and compared with experimental results. Furthermore, numerical examples of 3D wind flow around a surface-mounted cube with different Reynolds numbers are performed using DSGS model with Cabot near-wall model based on the present stabilized method to study the wind field and compared with experimental and numerical results. Finally, vortex structures for wind flow around a surface-mounted cube are studied by present numerical method. Stable and satisfactory results are obtained, which are consistent with most of the measurements even under coarse mesh.
A numerical study of the target system of an ADSS with different flow guides
K Arul Prakash; B V Rathish Kumar; G Biswas
2007-02-01
The mechanical design of the target module of an accelerator driven sub-critical nuclear reactor system (ADSS) calls for an analysis of the related thermal-hydraulic issues because of large amount of heat deposition in the spallation region during the course of nuclear interactions with the molten lead bismuth eutectic (LBE) target. The LBE also should carry the entire heat generated as a consequence of the spallation reaction. The problem of heat removal by the LBE is a challenging thermal-hydraulic issue. For this, one has to examine the flows of low Prandtl number fluids (LBE) in a complex ADSS geometry. In this study, the equations governing the laminar flow and thermal energy are solved numerically using the streamline upwind Petrov-Galerkin (SUPG) finite element (FE) method. The target systems with a straight and a nozzle guide have been considered. The principal purpose of the analysis is to trace the flow and temperature distribution and thereby to check the suitability of the flow guide in avoiding the recirculation or stagnation zones in the flow space that may lead to hot spots.
Multilevel first-order system least squares for PDEs
McCormick, S.
1994-12-31
The purpose of this talk is to analyze the least-squares finite element method for second-order convection-diffusion equations written as a first-order system. In general, standard Galerkin finite element methods applied to non-self-adjoint elliptic equations with significant convection terms exhibit a variety of deficiencies, including oscillations or nonmonotonicity of the solution and poor approximation of its derivatives, A variety of stabilization techniques, such as up-winding, Petrov-Galerkin, and stream-line diffusion approximations, have been introduced to eliminate these and other drawbacks of standard Galerkin methods. Yet, although significant progress has been made, convection-diffusion problems remain among the more difficult problems to solve numerically. The first-order system least-squares approach promises to overcome these deficiencies. This talk develops ellipticity estimates and discretization error bounds for elliptic equations (with lower order terms) that are reformulated as a least-squares problem for an equivalent first-order system. The main results are the proofs of ellipticity and optimal convergence of multiplicative and additive solvers of the discrete systems.
Study on the wind field and pollutant dispersion in street canyons using a stable numerical method
XIA Ji-yang; Dennis Y.C.LEUNG
2005-01-01
A stable finite element method for the time dependent Navier-Stokes equations was used for studying the wind flow and pollutant dispersion within street canyons. A three-step fractional method was used to solve the velocity field and the pressure field separately from the governing equations. The Streamline Upwind Petrov-Galerkin (SUPG) method was used to get stable numerical results. Numerical oscillation was minimized and satisfactory results can be obtained for flows at high Reynolds numbers. Simulating the flow over a square cylinder within a wide range of Reynolds numbers validates the wind field model. The Strouhal numbers obtained from the numerical simulation had a good agreement with those obtained from experiment. The wind field model developed in the present study is applied to simulate more complex flow phenomena in street canyons with two different building configurations. The results indicated that the flow at rooftop of buildings might not be assumed parallel to the ground as some numerical modelers did. A counter-clockwise rotating vortex may be found in street canyons with an inflow from the left to right. In addition, increasing building height can increase velocity fluctuations in the street canyon under certain circumstances, which facilitate pollutant dispersion. At high Reynolds numbers, the flow regimes in street canyons do not change with inflow velocity.
Feng, D.; Neuweiler, I.; Nackenhorst, U.
2017-02-01
We consider a model for biofilm growth in the continuum mechanics framework, where the growth of different components of biomass is governed by a time dependent advection-reaction equation. The recently developed time-discontinuous Galerkin (TDG) method combined with two different stabilization techniques, namely the Streamline Upwind Petrov Galerkin (SUPG) method and the finite increment calculus (FIC) method, are discussed as solution strategies for a multi-dimensional multi-species biofilm growth model. The biofilm interface in the model is described by a convective movement following a potential flow coupled to the reaction inside of the biofilm. Growth limiting substrates diffuse through a boundary layer on top of the biofilm interface. A rolling ball method is applied to obtain a boundary layer of constant height. We compare different measures of the numerical dissipation and dispersion of the simulation results in particular for those with non-trivial patterns. By using these measures, a comparative study of the TDG-SUPG and TDG-FIC schemes as well as sensitivity studies on the time step size, the spatial element size and temporal accuracy are presented.
NUMERICAL INVESTIGATION ON EXTRUDATE SWELL FOR VISCOELASTIC FLUID:USING MAXWELL MODEL
HUANG Shu-xin; LU Chuan-jing; JIANG Ti-qian
2004-01-01
The numerical investigation on extrudate swell through capillary die for viscoelastic fluid characteried by integral-type Maxwell constitutive equation was conducted by employing the finite element method with the calculation of viscoelastic extra stress in the conventional finite element. The method of avoiding singularity was also adopted by integrating the strain history of the Gauss points for each element near the wall and the free surface. The convergence solutions at high Weissenberg number can be obtained by using the appropriate methods to reduce errors and improve the speed of convergence of the calculation, which include adding a relaxation factor of velocity in iteration process, or enlarging the reference viscosity, or reducing the elapsed time. The highest Weissenberg number obtained here is up to 3.8, while the solution at the Weissenberg number of 3.75 was given in the previous work with similar extrudate swell ratio and the exit pressure drop by using differential Maxwell model with Elastic-Viscous Stress Split (EVSS) combined with Streamline Upwind Petrov-Galerkin (SUPG) scheme. The calculations indicated that the method of dealing with integral consti- tutive equation introduced in this paper is suitable in simulating viscoelastic flow characterized by integral constitutive equation at high elastic level.
Feng, D.; Neuweiler, I.; Nackenhorst, U.
2017-06-01
We consider a model for biofilm growth in the continuum mechanics framework, where the growth of different components of biomass is governed by a time dependent advection-reaction equation. The recently developed time-discontinuous Galerkin (TDG) method combined with two different stabilization techniques, namely the Streamline Upwind Petrov Galerkin (SUPG) method and the finite increment calculus (FIC) method, are discussed as solution strategies for a multi-dimensional multi-species biofilm growth model. The biofilm interface in the model is described by a convective movement following a potential flow coupled to the reaction inside of the biofilm. Growth limiting substrates diffuse through a boundary layer on top of the biofilm interface. A rolling ball method is applied to obtain a boundary layer of constant height. We compare different measures of the numerical dissipation and dispersion of the simulation results in particular for those with non-trivial patterns. By using these measures, a comparative study of the TDG-SUPG and TDG-FIC schemes as well as sensitivity studies on the time step size, the spatial element size and temporal accuracy are presented.
View-Dependent Streamline Deformation and Exploration
Tong, Xin; Edwards, John; Chen, Chun-Ming; Shen, Han-Wei; Johnson, Chris R.; Wong, Pak Chung
2016-07-01
Occlusion presents a major challenge in visualizing 3D flow and tensor fields using streamlines. Displaying too many streamlines creates a dense visualization filled with occluded structures, but displaying too few streams risks losing important features. We propose a new streamline exploration approach by visually manipulating the cluttered streamlines by pulling visible layers apart and revealing the hidden structures underneath. This paper presents a customized view-dependent deformation algorithm and an interactive visualization tool to minimize visual cluttering for visualizing 3D vector and tensor fields. The algorithm is able to maintain the overall integrity of the fields and expose previously hidden structures. Our system supports both mouse and direct-touch interactions to manipulate the viewing perspectives and visualize the streamlines in depth. By using a lens metaphor of different shapes to select the transition zone of the targeted area interactively, the users can move their focus and examine the vector or tensor field freely.
Sound propagation over screened ground under upwind conditions
Rasmussen, Karsten Bo
1996-01-01
in the frequency domain. The meteorological data representing the wind conditions have been determined by means of hot-wire anemometry in positions on both sides of the screen as well as directly over the screen. The theoretical model used for comparison is a hybrid approach. The sound field without a barrier......A screen on an absorbing ground is investigated experimentally and theoretically under upwind conditions. The experimental data are the result of scale model experiments in a 1:25 scale model. The sound propagation is measured using a triggered spark source with signal spectrum averaging...
A 3-D nonisothermal flow simulation and pulling force model for injection pultrusion processes
Mustafa, Ibrahim
1998-12-01
Injected Pultrusion (IP) is an efficient way of producing high quality, low cost, high volume and constant cross-section polymeric composites. This process has been developed recently, and the efforts to optimize it are still underway. This work is related to the development of a 3-D non-isothermal flow model for the IP processes. The governing equations for transport of mass, momentum and, energy are formulated by using a local volume averaging approach, and the Finite Element/Control Volume method is used to solve the system of equations numerically. The chemical species balance equation is solved in the Lagrangian frame of reference whereas the energy equation is solved using Galerkin, SU (Streamline Upwind), and SUPG (Streamline Upwind Petrov Galerkin) approaches. By varying degrees of freedom and the flow rates of the resin, it is shown that at high Peclet numbers the SUPG formulation performs better than the SU and the Galerkin methods in all cases. The 3-D model predictions for degree of cure and temperature are compared with a one dimensional analytical solution and the results are found satisfactory. Moreover, by varying the Brinkman Number, it is shown that the effect of viscous dissipation is insignificant. The 3-D flow simulations have been carried out for both thin and thick parts and the results are compared with the 2-D model. It is shown that for thick parts 2-D simulations render erroneous results. The effect of changing permeability on the flow fronts is also addressed. The effect of increasing taper angle on the model prediction is also investigated. A parametric study is conducted to isolate optimum conditions for both isothermal and non-isothermal cases using a straight rectangular die and a die with a tapered inlet. Finally, a simple pulling force model is developed and the pulling force required to pull the carbon-epoxy fiber resin system is estimated for dies of varying tapered inlet.
Streamlined Islands in Ares Valles
2002-01-01
(Released 10 June 2002) The Science Although liquid water is not stable on the surface of Mars today, there is substantial geologic evidence that large quantities of water once flowed across the surface in the distant past. Streamlined islands, shown here, are one piece of evidence for this ancient water. The tremendous force of moving water, possibly from a catastrophic flood, carved these teardrop-shaped islands within a much larger channel called Ares Valles. The orientation of the islands can be used as an indicator of the direction the water flowed. The islands have a blunt end that is usually associated with an obstacle, commonly an impact crater. The crater is resistant to erosion and creates a geologic barrier around which the water must flow. As the water flows past the obstacle, its erosive power is directed outward, leaving the area in the lee of the obstacle relatively uneroded. However, some scientists have also argued that the area in the lee of the obstacle might be a depositional zone, where material is dropped out of the water as it briefly slows. The ridges observed on the high-standing terrain in the leeward parts of the islands may be benches carved into the rock that mark the height of the water at various times during the flood, or they might be indicative of layering in the leeward rock. As the water makes its way downstream, the interference of the water flow by the obstacle is reduced, and the water that was diverted around the obstacle rejoins itself at the narrow end of the island. Therefore, the direction of the water flow is parallel to the orientation of the island, and the narrow end of the island points downstream. In addition to the streamlined islands, the channel floor exhibits fluting that is also suggestive of flowing water. The flutes (also known as longitudinal grooves) are also parallel to the direction of flow, indicating that the water flow was turbulent and probably quite fast, which is consistent with the hypothesized
Creating customer value by streamlining business processes.
Vantrappen, H
1992-02-01
Much of the strategic preoccupation of senior managers in the 1990s is focusing on the creation of customer value. Companies are seeking competitive advantage by streamlining the three processes through which they interact with their customers: product creation, order handling and service assurance. 'Micro-strategy' is a term which has been coined for the trade-offs and decisions on where and how to streamline these three processes. The article discusses micro-strategies applied by successful companies.
无
2006-01-01
In this paper, we study the semi-discrete mortar upwind finite volume element method with the Crouzeix-Raviart element for the parabolic convection diffusion problems.It is proved that the semi-discrete mortar upwind finite volume element approximations derived are convergent in the H1- and L2-norms.
POINTWISE AND UPWIND DISCRETIZATIONS OF SOURCE TERMS IN OPEN-CHANNEL FLOOD ROUTING
MENG Jian; CAO Zhi-xian; CARLING Paul A.
2006-01-01
Upwind algorithms are becoming progressively popular for river flood routing due to their capability of resolving trans-critical flow regimes. For consistency, these algorithms suggest natural upwind discretization of the source term, which may be essential for natural channels with irregular geometry. Yet applications of these upwind algorithms to natural river flows are rare, and in such applications the traditional and simpler pointwise, rather than upwind discretization of the source term is used. Within the framework of a first-order upwind algorithm, this paper presents a comparison of upwind and pointwise discretizations of the source term. Numerical simulations were carried out for a selected irregular channel comprising a pool-riffle sequence in the River Lune, England with observed data. It is shown that the impact of pointwise discretization, compared to the upwind, is appreciable mainly in flow zones with the Froude number closer to or larger than unity. The discrepancy due to pointwise and upwind discretizations of the source term is negligible in flow depth and hence in water surface elevation, but well manifested in mean velocity and derived flow quantities. Also the occurrence of flow reversal and equalisation over the pool-riffle sequence in response to increasing discharges is demonstrated.
Impact assessment: Eroding benefits through streamlining?
Bond, Alan, E-mail: alan.bond@uea.ac.uk [School of Environmental Sciences, University of East Anglia (United Kingdom); School of Geo and Spatial Sciences, North-West University (South Africa); Pope, Jenny, E-mail: jenny@integral-sustainability.net [Integral Sustainability (Australia); Curtin University Sustainability Policy Institute (Australia); Morrison-Saunders, Angus, E-mail: A.Morrison-Saunders@murdoch.edu.au [School of Geo and Spatial Sciences, North-West University (South Africa); Environmental Science, Murdoch University (Australia); Retief, Francois, E-mail: francois.retief@nwu.ac.za [School of Geo and Spatial Sciences, North-West University (South Africa); Gunn, Jill A.E., E-mail: jill.gunn@usask.ca [Department of Geography and Planning and School of Environment and Sustainability, University of Saskatchewan (Canada)
2014-02-15
This paper argues that Governments have sought to streamline impact assessment in recent years (defined as the last five years) to counter concerns over the costs and potential for delays to economic development. We hypothesise that this has had some adverse consequences on the benefits that subsequently accrue from the assessments. This hypothesis is tested using a framework developed from arguments for the benefits brought by Environmental Impact Assessment made in 1982 in the face of the UK Government opposition to its implementation in a time of economic recession. The particular benefits investigated are ‘consistency and fairness’, ‘early warning’, ‘environment and development’, and ‘public involvement’. Canada, South Africa, the United Kingdom and Western Australia are the jurisdictions tested using this framework. The conclusions indicate that significant streamlining has been undertaken which has had direct adverse effects on some of the benefits that impact assessment should deliver, particularly in Canada and the UK. The research has not examined whether streamlining has had implications for the effectiveness of impact assessment, but the causal link between streamlining and benefits does sound warning bells that merit further investigation. -- Highlights: • Investigation of the extent to which government has streamlined IA. • Evaluation framework was developed based on benefits of impact assessment. • Canada, South Africa, the United Kingdom, and Western Australia were examined. • Trajectory in last five years is attrition of benefits of impact assessment.
Systems Biology and Ecology of Streamlined Bacterioplankton
Giovannoni, S. J.
2014-12-01
The salient feature of streamlined cells is their small genome size, but "streamlining" refers more generally to selection that favors minimization of cell size and complexity. The essence of streamlining theory is that selection is most efficient in organisms that have large effective population sizes, and, in nutrient-limited systems, favors cell architecture that minimizes resources required for replication. Regardless of the cause of genome reduction, lost coding potential eventually dictates loss of function, raising the questions, what genome features are expendable, and how do cells become highly successful with a minimal genomic repertoire? One consequence of reductive evolution in streamlined organisms is atypical patterns of prototrophy, for example the recent discovery of a requirement for the thiamin precursor 4-amino-5-hydroxymethyl-2-methylpyrimidine in some plankton taxa. Examples such as this fit within the framework of the Black Queen Hypothesis, which describes genome reduction that results in reliance on community goods and increased community connectivity. Other examples of genome reduction include losses of regulatory functions, or replacement with simpler regulatory systems, and increased metabolic integration. In one such case, in the order Pelagibacterales, the PII system for regulating responses to N limitation has been replaced with a simpler system composed of fewer genes. Both the absence of common regulatory systems and atypical patterns of prototrophy have been linked to difficulty in culturing Pelagibacterales, lending credibility to the idea that streamlining might broadly explain the phenomenon of the uncultured microbial majority. The success of streamlined osmotrophic bacterioplankton suggests that they successfully compete for labile organic matter and capture a large share of this resource, but an alternative theory postulates they are not good resource competitors and instead prosper by avoiding predation. The answers to these
77 FR 14700 - Streamlining Inherited Regulations
2012-03-13
... April 3, 2012. \\1\\ 76 FR 75825. The Bureau received a joint request from several industry and consumer... Consumer Law Center. For the reasons described in the joint request for an extension, the Bureau is...; ] BUREAU OF CONSUMER FINANCIAL PROTECTION 12 CFR Chapter X Streamlining Inherited Regulations...
Streamlining the Bankability Process using International Standards
Kurtz, Sarah [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Repins, Ingrid L [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kelly, George [Sunset Technology, Mount Airy, MD; Ramu, Govind [SunPower, San Jose, California; Heinz, Matthias [TUV Rheinland, Cologne, Germany; Chen, Yingnan [CGC (China General Certification Center), Beijing; Wohlgemuth, John [PowerMark, Union Hall, VA; Lokanath, Sumanth [First Solar, Tempe, Arizona; Daniels, Eric [Suncycle USA, Frederick MD; Hsi, Edward [Swiss RE, Zurich, Switzerland; Yamamichi, Masaaki [RTS, Trumbull, CT
2017-09-27
NREL has supported the international efforts to create a streamlined process for documenting bankability and/or completion of each step of a PV project plan. IECRE was created for this purpose in 2014. This poster describes the goals, current status of this effort, and how individuals and companies can become involved.
Streamlining Exceptional Student Placement with PERT.
Radencich, Marguerite C.
1985-01-01
The article explains the usefulness of PERT (Program Evaluation and Review Technique) in streamlining exceptional student referral processes. With PERT, realistic time and personnel needs can be established, and the status of every referral can be known at all times. The initial step in PERT breaks the process into small manageable units and…
Probabilistic Analysis of the Upwind Scheme for Transport Equations
Delarue, François; Lagoutière, Frédéric
2011-01-01
We provide a probabilistic analysis of the upwind scheme for d-dimensional transport equations. We associate a Markov chain with the numerical scheme and then obtain a backward representation formula of Kolmogorov type for the numerical solution. We then understand that the error induced by the scheme is governed by the fluctuations of the Markov chain around the characteristics of the flow. We show, in various situations, that the fluctuations are of diffusive type. As a by-product, we recover recent results due to Merlet and Vovelle (Numer Math 106: 129-155, 2007) and Merlet (SIAM J Numer Anal 46(1):124-150, 2007): we prove that the scheme is of order 1/2 in {L^{infty}([0,T],L^1(mathbb R^d))} for an integrable initial datum of bounded variation and of order 1/2- ɛ, for all ɛ > 0, in {L^{infty}([0,T] × mathbb R^d)} for an initial datum of Lipschitz regularity. Our analysis provides a new interpretation of the numerical diffusion phenomenon.
Applying Upwind Godunov Methods to Calculate Two—Phase Mixture Conservation Laws
Zeidan, D.
2010-09-01
This paper continues a previous work (ICNAAM 2009; AIP Conference Proceedings, 1168, 601-604) on solving a hyperbolic conservative model for compressible gas—solid mixture flow using upwind Godunov methods. The numerical resolution of the model from Godunov first—order upwind and MUSCL—Hancock methods are reported. Both methods are based on the HLL Riemann solver in the framework of finite volume techniques. Calculation results are presented for a series of one—dimensional test problems. The results show that upwind Godunov methods are accurate and robust enough for two—phase mixture conservation laws.
Hydrodynamic Drag on Streamlined Projectiles and Cavities
Jetly, Aditya
2016-04-19
The air cavity formation resulting from the water-entry of solid objects has been the subject of extensive research due to its application in various fields such as biology, marine vehicles, sports and oil and gas industries. Recently we demonstrated that at certain conditions following the closing of the air cavity formed by the initial impact of a superhydrophobic sphere on a free water surface a stable streamlined shape air cavity can remain attached to the sphere. The formation of superhydrophobic sphere and attached air cavity reaches a steady state during the free fall. In this thesis we further explore this novel phenomenon to quantify the drag on streamlined shape cavities. The drag on the sphere-cavity formation is then compared with the drag on solid projectile which were designed to have self-similar shape to that of the cavity. The solid projectiles of adjustable weight were produced using 3D printing technique. In a set of experiments on the free fall of projectile we determined the variation of projectiles drag coefficient as a function of the projectiles length to diameter ratio and the projectiles specific weight, covering a range of intermediate Reynolds number, Re ~ 104 – 105 which are characteristic for our streamlined cavity experiments. Parallel free fall experiment with sphere attached streamlined air cavity and projectile of the same shape and effective weight clearly demonstrated the drag reduction effect due to the stress-free boundary condition at cavity liquid interface. The streamlined cavity experiments can be used as the upper bound estimate of the drag reduction by air layers naturally sustained on superhydrophobic surfaces in contact with water. In the final part of the thesis we design an experiment to test the drag reduction capacity of robust superhydrophobic coatings deposited on the surface of various model vessels.
Thornton, E. A.
1979-01-01
Three practical problems in conduction/forced convection heat transfer are analyzed using a simplified engineering formulation of convective finite elements. Upwind and conventional finite element solutions are compared for steady-state and transient applications.
48 CFR 52.207-2 - Notice of Streamlined Competition.
2010-10-01
... Competition. 52.207-2 Section 52.207-2 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION....207-2 Notice of Streamlined Competition. As prescribed in 7.305(b), insert the following provision: Notice of Streamlined Competition (MAY 2006) (a) This solicitation is part of a streamlined...
Simulation of upwind maneuvering of a sailing yacht
Harris, Daniel Hartrick
A time domain maneuvering simulation of an IACC class yacht suitable for the analysis of unsteady upwind sailing including tacking is presented. The simulation considers motions in six degrees of freedom. The hydrodynamic and aerodynamic loads are calculated primarily with unsteady potential theory supplemented by empirical viscous models. The hydrodynamic model includes the effects of incident waves. Control of the rudder is provided by a simple rate feedback autopilot which is augmented with open loop additions to mimic human steering. The hydrodynamic models are based on the superposition of force components. These components fall into two groups, those which the yacht will experience in calm water, and those due to incident waves. The calm water loads are further divided into zero Froude number, or "double body" maneuvering loads, hydrostatic loads, gravitational loads, free surface radiation loads, and viscous/residual loads. The maneuvering loads are calculated with an unsteady panel code which treats the instantaneous geometry of the yacht below the undisturbed free surface. The free surface radiation loads are calculated via convolution of impulse response functions derived from seakeeping strip theory. The viscous/residual loads are based upon empirical estimates. The aerodynamic model consists primarily of a database of steady state sail coefficients. These coefficients treat the individual contributions to the total sail force of a number of chordwise strips on both the main and jib. Dynamic effects are modeled by using the instantaneous incident wind velocity and direction as the independent variables for the sail load contribution of each strip. The sail coefficient database was calculated numerically with potential methods and simple empirical viscous corrections. Additional aerodynamic load calculations are made to determine the parasitic contributions of the rig and hull. Validation studies compare the steady sailing hydro and aerodynamic loads
Reduction of air pollution levels downwind of a road with an upwind noise barrier
Enayati Ahangar, Faraz; Heist, David; Perry, Steven; Venkatram, Akula
2017-04-01
We propose a dispersion model to estimate the impact of a solid noise barrier upwind of a highway on air pollution concentrations downwind of the road. The model, based on data from wind tunnel experiments conducted by Heist et al. (2009), assumes that the upwind barrier has two main effects: 1) it creates a recirculation zone behind the barrier that sweeps the emissions from the highway back towards the wall, and 2) it enhances vertical dispersion and initial mixing. By combining the upwind barrier model with the mixed wake model for a downwind barrier described in Schulte et al. (2014), we are able to model dispersion of emissions from a highway with noise barriers on both sides. The model provides a good description of measurements made in the wind tunnel. The presence of an upwind barrier causes reductions in concentrations relative to those measured downwind of a road with no barriers. The reduction can be as large as that caused by a downwind barrier if the recirculation zone covers the width of the highway. Barriers on both sides of the highway result in larger reductions downwind of the barriers than those caused by a single barrier either upwind or downwind. As expected, barrier effects are small beyond 10 barrier heights downwind of the highway. We also propose a tentative model to estimate on-road concentrations within the recirculation zone induced by the upwind barrier.
Streamlining of Plant Patches in Streams
Sand-Jensen, Kaj; Pedersen, Morten Lauge
2008-01-01
area or root area was significantly lower in shallow water . Canopy shape and indices of streamlining did not change significantly with approach velocity (0.02-0.40 m s)1), either because canopy shape is not sensitive to approach velocity or summer velocities were too low to induce such changes. 3......1. Plants in shallow streams often grow in well-defined monospecific patches experiencing a predictable unidirectional flow, though of temporally variable velocity. During maximum patch development in summer we studied: (i) the shape and streamlining of 59 patches of Callitriche cophocarpa, (ii...... averaged 0.25. The canopy and root area of the patches were more elongate and slender in sites with shallow water, where currents accelerate alongside patches and restrict lateral expansion, compared to deeper sites where currents can pass above the canopy. Similarly, the frontal area relative to planform...
Fast placement of evenly spaced streamlines on curvilinear grid surfaces
Mao, Xiaoyang; Higashida, Hidenori; Imamiya, Atsumi
2000-02-01
The success of using streamline technique for visualizing a vector field usually depends largely on the choosing of adequate seed points. This paper propose a new technique for automatically placing seed points to create evenly spaced streamlines on 3D parametric surfaces found in curvilinear grids. The new technique extends Jobard and Lefer's distance-based single pass approach for placing streamlines in the 2D computational space of the surface. Experimental result show that the new technique produces streamline images of competitive quality at much lower computational expense image-guided progressive refinement approach. A method for compensating the visual streamline density distortion caused by projection is also presented.
Streamlining the RI/FS process
Dumas, L.; Doss, R.C.
1998-07-01
In 1994, Pacific Gas and Electric Company (PG and E) contracted with CH2M HILL to manage remedial investigations and feasibility studies (RI/FS) at its former manufactured gas plant (MGP) sites in Chico, Willows, and Marysville, California. These three sites had similar histories, MGP-related contaminants, similar geologic settings, and geographically were close together. Recognizing the advantages that may be gained, both in time and money, by streamlining the RI/FS process, PG and E and CH2M HILL combined the sites into one project. From the start of the project, PG and E and CH2M HILL looked for an implemented changes to the RI/FS process to streamline the project. These changes included combining deliverables, linking field programs at the three sites, and negotiating bulk discounts on laboratory and other services by combining the work to be done at the three sites under one contract. CH2M HILL later proposed additional measures to streamline the project that were eventually adopted by both PG and E and the regulatory agencies. PG and E and CH2M HILL are currently working with the regulatory agencies to negotiate realistic measures to address contaminants in soil and groundwater, and are jointly preparing the FS with the regulatory agencies using a unique means of documentation.
Analysis and Improvement of Upwind and Centered Schemes on Quadrilateral and Triangular Meshes
Huynh, H. T.
2003-01-01
Second-order accurate upwind and centered schemes are presented in a framework that facilitates their analysis and comparison. The upwind scheme employed consists of a reconstruction step (MUSCL approach) followed by an upwind step (Roe's flux-difference splitting). The two centered schemes are of Lax-Friedrichs (L-F) type. They are the nonstaggered versions of the Nessyahu-Tadmor (N-T) scheme and the CE/SE method with epilson = 1/2. The upwind scheme is extended to the case of two spatial dimensions (2D) in a straightforward manner. The N-T and CE/SE schemes are extended in a manner similar to the 2D extensions of the CE/SE scheme by Wang and Chang for a triangular mesh and by Zhang, Yu, and Chang for a quadrilateral mesh. The slope estimates, however, are simplified. Fourier stability and accuracy analyses are carried out for these schemes for the standard 1D and the 2D quadrilateral mesh cases. In the nonstandard case of a triangular mesh, the triangles must be paired up when analyzing the upwind and N-T schemes. An observation resulting in an extended N-T scheme which is faster and uses only one-third of the storage for flow data compared with the CE/SE method is presented. Numerical results are shown. Other improvements to the schemes are discussed.
Lightroom 5 streamlining your digital photography process
Sylvan, Rob
2014-01-01
Manage your images with Lightroom and this beautifully illustrated guide Image management can soak up huge amounts of a photographer's time, but help is on hand. This complete guides teaches you how to use Adobe Lightroom 5 to import, manage, edit, and showcase large quantities of images with impressive results. The authors, both professional photographers and Lightroom experts, walk you through step by step, demonstrating real-world techniques as well as a variety of practical tips, tricks, and shortcuts that save you time. Streamline image management tasks like a pro, and get back to doing
Streamlining environmental product declarations: a stage model
Lefebvre, Elisabeth; Lefebvre, Louis A.; Talbot, Stephane; Le Hen, Gael
2001-02-01
General public environmental awareness and education is increasing, therefore stimulating the demand for reliable, objective and comparable information about products' environmental performances. The recently published standard series ISO 14040 and ISO 14025 are normalizing the preparation of Environmental Product Declarations (EPDs) containing comprehensive information relevant to a product's environmental impact during its life cycle. So far, only a few environmentally leading manufacturing organizations have experimented the preparation of EPDs (mostly from Europe), demonstrating its great potential as a marketing weapon. However the preparation of EPDs is a complex process, requiring collection and analysis of massive amounts of information coming from disparate sources (suppliers, sub-contractors, etc.). In a foreseeable future, the streamlining of the EPD preparation process will require product manufacturers to adapt their information systems (ERP, MES, SCADA) in order to make them capable of gathering, and transmitting the appropriate environmental information. It also requires strong functional integration all along the product supply chain in order to ensure that all the information is made available in a standardized and timely manner. The goal of the present paper is two fold: first to propose a transitional model towards green supply chain management and EPD preparation; second to identify key technologies and methodologies allowing to streamline the EPD process and subsequently the transition toward sustainable product development
The Influence of Streamlined Music on Cognition and Mood
Mossbridge, Julia
2016-01-01
Recent advances in sound engineering have led to the development of so-called streamlined music designed to reduce exogenous attention and improve endogenous attention. Although anecdotal reports suggest that streamlined music does indeed improve focus on daily work tasks and may improve mood, the specific influences of streamlined music on cognition and mood have yet to be examined. In this paper, we report the results of a series of online experiments that examined the impact of one form of...
Similarity-Guided Streamline Placement with Error Evaluation
Chen, Y; Cohen, J D; Krolik, J H
2007-08-15
Most streamline generation algorithms either provide a particular density of streamlines across the domain or explicitly detect features, such as critical points, and follow customized rules to emphasize those features. However, the former generally includes many redundant streamlines, and the latter requires Boolean decisions on which points are features (and may thus suffer from robustness problems for real-world data). We take a new approach to adaptive streamline placement for steady vector fields in 2D and 3D. We define a metric for local similarity among streamlines and use this metric to grow streamlines from a dense set of candidate seed points. The metric considers not only Euclidean distance, but also a simple statistical measure of shape and directional similarity. Without explicit feature detection, our method produces streamlines that naturally accentuate regions of geometric interest. In conjunction with this method, we also propose a quantitative error metric for evaluating a streamline representation based on how well it preserves the information from the original vector field. This error metric reconstructs a vector field from points on the streamline representation and computes a difference of the reconstruction from the original vector field.
姚磊华
1997-01-01
A generalized upwind scheme with fractional steps for 3-D mathematical models of convection dominating groundwater quality is suggested. The mass transport equation is split into a convection equation and a dispersive equation. The generalized upwind scheme is used to solve the convection equation and the finite element method is used to compute the dispersive equation. These procedures which not only overcome the phenomenon of the negative concentration and numerical dispersion appear frequently with normal FEM or FDM to solve models of convection dominating groundwater transport but also avoid the step for computing each node velocity give a more suitable method to calculate the concentrations of the well points.
Large Scale Modelling of Glow Discharges or Non - Plasmas
Shankar, Sadasivan
The Electron Velocity Distribution Function (EVDF) in the cathode fall of a DC helium glow discharge was evaluated from a numerical solution of the Boltzmann Transport Equation(BTE). The numerical technique was based on a Petrov-Galerkin technique and a unique combination of streamline upwinding with self -consistent feedback-based shock-capturing. EVDF for the cathode fall was solved at 1 Torr, as a function of position x, axial velocity v_{rm x}, radial velocity v_{rm r}, and time t. The electron-neutral collisions consisted of elastic, excitation, and ionization processes. The algorithm was optimized and vectorized to speed execution by more than a factor of 10 on CRAY-XMP. Efficient storage schemes were used to save the memory allocation required by the algorithm. The analysis of the solution of BTE was done in terms of the 8-moments that were evaluated. Higher moments were found necessary to study the momentum and energy fluxes. The time and length scales were estimated and used as a basis for the characterization of DC glow discharges. Based on an exhaustive study of Knudsen numbers, it was observed that the electrons in the cathode fall were in the transition or Boltzmann regime. The shortest relaxation time was the momentum relaxation and the longest times were the ionization and energy relaxation times. The other times in the processes were that for plasma reaction, diffusion, convection, transit, entropy relaxation, and that for mean free flight between the collisions. Different models were classified based on the moments, time scales, and length scales in their applicability to glow discharges. These consisted of BTE with different number af phase and configuration dimensions, Bhatnagar-Gross-Krook equation, moment equations (e.g. Drift-Diffusion, Drift-Diffusion-Inertia), and spherical harmonic expansions.
Sahai, A.; Mansour, N. N.; Lopez, B.; Panesi, M.
2017-05-01
This work addresses the modeling of high pressure electric discharge in an arc-heated wind tunnel. The combined numerical solution of Poisson’s equation, radiative transfer equations, and the set of Favre-averaged thermochemical nonequilibrium Navier-Stokes equations allows for the determination of the electric, radiation, and flow fields, accounting for their mutual interaction. Semi-classical statistical thermodynamics is used to determine the plasma thermodynamic properties, while transport properties are obtained from kinetic principles with the Chapman-Enskog method. A multi-temperature formulation is used to account for thermal non-equilibrium. Finally, the turbulence closure of the flow equations is obtained by means of the Spalart-Allmaras model, which requires the solution of an additional scalar transport equation. A Streamline upwind Petrov-Galerkin stabilized finite element formulation is employed to solve the Navier-Stokes equation. The electric field equation is solved using the standard Galerkin formulation. A stable formulation for the radiative transfer equations is obtained using the least-squares finite element method. The developed simulation framework has been applied to investigate turbulent plasma flows in the 20 MW Aerodynamic Heating Facility at NASA Ames Research Center. The current model is able to predict the process of energy addition and re-distribution due to Joule heating and thermal radiation, resulting in a hot central core surrounded by colder flow. The use of an unsteady three-dimensional treatment also allows the asymmetry due to a dynamic electric arc attachment point in the cathode chamber to be captured accurately. The current work paves the way for detailed estimation of operating characteristics for arc-heated wind tunnels which are critical in testing thermal protection systems.
Quantum mechanical streamlines. I - Square potential barrier
Hirschfelder, J. O.; Christoph, A. C.; Palke, W. E.
1974-01-01
Exact numerical calculations are made for scattering of quantum mechanical particles hitting a square two-dimensional potential barrier (an exact analog of the Goos-Haenchen optical experiments). Quantum mechanical streamlines are plotted and found to be smooth and continuous, to have continuous first derivatives even through the classical forbidden region, and to form quantized vortices around each of the nodal points. A comparison is made between the present numerical calculations and the stationary wave approximation, and good agreement is found between both the Goos-Haenchen shifts and the reflection coefficients. The time-independent Schroedinger equation for real wavefunctions is reduced to solving a nonlinear first-order partial differential equation, leading to a generalization of the Prager-Hirschfelder perturbation scheme. Implications of the hydrodynamical formulation of quantum mechanics are discussed, and cases are cited where quantum and classical mechanical motions are identical.
A streamlined failure mode and effects analysis
Ford, Eric C., E-mail: eford@uw.edu; Smith, Koren; Terezakis, Stephanie; Croog, Victoria; Gollamudi, Smitha; Gage, Irene; Keck, Jordie; DeWeese, Theodore; Sibley, Greg [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD 21287 (United States)
2014-06-15
Purpose: Explore the feasibility and impact of a streamlined failure mode and effects analysis (FMEA) using a structured process that is designed to minimize staff effort. Methods: FMEA for the external beam process was conducted at an affiliate radiation oncology center that treats approximately 60 patients per day. A structured FMEA process was developed which included clearly defined roles and goals for each phase. A core group of seven people was identified and a facilitator was chosen to lead the effort. Failure modes were identified and scored according to the FMEA formalism. A risk priority number,RPN, was calculated and used to rank failure modes. Failure modes with RPN > 150 received safety improvement interventions. Staff effort was carefully tracked throughout the project. Results: Fifty-two failure modes were identified, 22 collected during meetings, and 30 from take-home worksheets. The four top-ranked failure modes were: delay in film check, missing pacemaker protocol/consent, critical structures not contoured, and pregnant patient simulated without the team's knowledge of the pregnancy. These four failure modes hadRPN > 150 and received safety interventions. The FMEA was completed in one month in four 1-h meetings. A total of 55 staff hours were required and, additionally, 20 h by the facilitator. Conclusions: Streamlined FMEA provides a means of accomplishing a relatively large-scale analysis with modest effort. One potential value of FMEA is that it potentially provides a means of measuring the impact of quality improvement efforts through a reduction in risk scores. Future study of this possibility is needed.
袁益让
2002-01-01
For compressible two-phase displacement problem, a kind of upwind operator splitting finite difference schemes is put forward and make use of operator splitting, of calculus of variations, multiplicative commutation rule of difference operators, decomposition of high order difference operators and prior estimates are adopted. Optimal order estinates in L2 norm are derived to determine the error in the approximate solution.
Effects of upwinding on the solution of a 1-D advection-diffusion problem
Sahai, V.
1991-12-01
A one-dimensional advection-diffusion problem whose solution is known was solved using TOPAZ2D. Two numerical upwinding techniques were used to damp out the numerical oscillations that occur. Comparisons between the exact and numerical solution were made.
Flow and wakes in large wind farms: Final report for UpWind WP8
Barthelmie, Rebecca Jane; Frandsen, Sten Tronæs; Rathmann, Ole;
This report summarises the research undertaken through the European Commission funded project UpWind Wp8:Flow. The objective of the work was to develop understanding of flow in large wind farms and to evaluate models of power losses due to wind turbine wakes focusing on complex terrain and offsho...
Streamline curvature and bed resistance in shallow water flow
De Vriend, H.J.
1979-01-01
The relationship between streamline curvature and bed resistance in shallow water flow with little side constraint, as derived in 1970 by H.J. Schoemaker, is reconsidered. Schoemaker concluded that the bed resistance causes the curvature of a free streamline to grow exponentially with the distance a
Scalable Computation of Streamlines on Very Large Datasets
Pugmire, David; Childs, Hank; Garth, Christoph; Ahern, Sean; Weber, Gunther H.
2009-09-01
Understanding vector fields resulting from large scientific simulations is an important and often difficult task. Streamlines, curves that are tangential to a vector field at each point, are a powerful visualization method in this context. Application of streamline-based visualization to very large vector field data represents a significant challenge due to the non-local and data-dependent nature of streamline computation, and requires careful balancing of computational demands placed on I/O, memory, communication, and processors. In this paper we review two parallelization approaches based on established parallelization paradigms (static decomposition and on-demand loading) and present a novel hybrid algorithm for computing streamlines. Our algorithm is aimed at good scalability and performance across the widely varying computational characteristics of streamline-based problems. We perform performance and scalability studies of all three algorithms on a number of prototypical application problems and demonstrate that our hybrid scheme is able to perform well in different settings.
Streamlining HIV Testing for HIV Preexposure Prophylaxis
Leigler, Teri; Kallas, Esper; Schechter, Mauro; Sharma, Usha; Glidden, David; Grant, Robert M.
2014-01-01
HIV-testing algorithms for preexposure prophylaxis (PrEP) should be optimized to minimize the risk of drug resistance, the time off PrEP required to evaluate false-positive screening results, and costs and to expedite the start of therapy for those confirmed to be infected. HIV rapid tests (RTs) for anti-HIV antibodies provide results in less than 1 h and can be conducted by nonlicensed staff at the point of care. In many regions, Western blot (WB) testing is required to confirm reactive RT results. WB testing, however, causes delays in diagnosis and adds expense. The iPrEx study evaluated the safety and efficacy of daily oral emtricitabine-tenofovir disoproxil fumarate among HIV-seronegative men and transgender women who have sex with men: HIV infection was assessed with two RTs plus WB confirmation, followed by HIV-1 plasma viral load testing. During the iPrEx study, there were 51,260 HIV status evaluations among 2,499 volunteers using RTs: 142 (0.28%) had concordant positive results (100% were eventually confirmed) and 19 (0.04%) had discordant results among 14 participants; 11 were eventually determined to be HIV infected. A streamlined approach using only one RT to screen and a second RT to confirm (without WB) would have had nearly the same accuracy. Discrepant RT results are best evaluated with nucleic acid testing, which would also increase sensitivity. PMID:25378570
Streamlined expressed protein ligation using split inteins.
Vila-Perelló, Miquel; Liu, Zhihua; Shah, Neel H; Willis, John A; Idoyaga, Juliana; Muir, Tom W
2013-01-09
Chemically modified proteins are invaluable tools for studying the molecular details of biological processes, and they also hold great potential as new therapeutic agents. Several methods have been developed for the site-specific modification of proteins, one of the most widely used being expressed protein ligation (EPL) in which a recombinant α-thioester is ligated to an N-terminal Cys-containing peptide. Despite the widespread use of EPL, the generation and isolation of the required recombinant protein α-thioesters remain challenging. We describe here a new method for the preparation and purification of recombinant protein α-thioesters using engineered versions of naturally split DnaE inteins. This family of autoprocessing enzymes is closely related to the inteins currently used for protein α-thioester generation, but they feature faster kinetics and are split into two inactive polypeptides that need to associate to become active. Taking advantage of the strong affinity between the two split intein fragments, we devised a streamlined procedure for the purification and generation of protein α-thioesters from cell lysates and applied this strategy for the semisynthesis of a variety of proteins including an acetylated histone and a site-specifically modified monoclonal antibody.
Ricchiuto, M.; Filippini, A. G.
2014-08-01
In this paper we consider the solution of the enhanced Boussinesq equations of Madsen and Sørensen (1992) [55] by means of residual based discretizations. In particular, we investigate the applicability of upwind and stabilized variants of continuous Galerkin finite element and Residual Distribution schemes for the simulation of wave propagation and transformation over complex bathymetries. These techniques have been successfully applied to the solution of the nonlinear Shallow Water equations (see e.g. Hauke (1998) [39] and Ricchiuto and Bollermann (2009) [61]). In a first step toward the construction of a hybrid model coupling the enhanced Boussinesq equations with the Shallow Water equations in breaking regions, this paper shows that equal order and even low order (second) upwind/stabilized techniques can be used to model non-hydrostatic wave propagation over complex bathymetries. This result is supported by theoretical (truncation and dispersion) error analyses, and by thorough numerical validation.
CONVERGENCE OF AN EXPLICIT UPWIND FINITE ELEMENT METHOD TO MULTI-DIMENSIONAL CONSERVATION LAWS
Jin-chao Xu; Lung-an Ying
2001-01-01
An explicit upwind finite element method is given for the numerical computation to multi-dimensional scalar conservation laws. It is proved that this scheme is consistent to the equation and monotone, and the approximate solution satisfies discrete entropy inequality.To guarantee the limit of approximate solutions to be a measure valued solution, we prove an energy estimate. Then the Lp strong convergence of this scheme is proved.
Proposal - Streamline forest data analysis on R4 refuges
US Fish and Wildlife Service, Department of the Interior — Proposal to obtain software to streamline analysis of forested habitat inventories that use parameters from Desired Forest Condition. This would include data upload...
Central upwind scheme for a compressible two-phase flow model.
Munshoor Ahmed
Full Text Available In this article, a compressible two-phase reduced five-equation flow model is numerically investigated. The model is non-conservative and the governing equations consist of two equations describing the conservation of mass, one for overall momentum and one for total energy. The fifth equation is the energy equation for one of the two phases and it includes source term on the right-hand side which represents the energy exchange between two fluids in the form of mechanical and thermodynamical work. For the numerical approximation of the model a high resolution central upwind scheme is implemented. This is a non-oscillatory upwind biased finite volume scheme which does not require a Riemann solver at each time step. Few numerical case studies of two-phase flows are presented. For validation and comparison, the same model is also solved by using kinetic flux-vector splitting (KFVS and staggered central schemes. It was found that central upwind scheme produces comparable results to the KFVS scheme.
Scanning of wind turbine upwind conditions: numerical algorithm and first applications
Calaf, Marc; Cortina, Gerard; Sharma, Varun; Parlange, Marc B.
2014-11-01
Wind turbines still obtain in-situ meteorological information by means of traditional wind vane and cup anemometers installed at the turbine's nacelle, right behind the blades. This has two important drawbacks: 1-turbine misalignment with the mean wind direction is common and energy losses are experienced; 2-the near-blade monitoring does not provide any time to readjust the profile of the wind turbine to incoming turbulence gusts. A solution is to install wind Lidar devices on the turbine's nacelle. This technique is currently under development as an alternative to traditional in-situ wind anemometry because it can measure the wind vector at substantial distances upwind. However, at what upwind distance should they interrogate the atmosphere? A new flexible wind turbine algorithm for large eddy simulations of wind farms that allows answering this question, will be presented. The new wind turbine algorithm timely corrects the turbines' yaw misalignment with the changing wind. The upwind scanning flexibility of the algorithm also allows to track the wind vector and turbulent kinetic energy as they approach the wind turbine's rotor blades. Results will illustrate the spatiotemporal evolution of the wind vector and the turbulent kinetic energy as the incoming flow approaches the wind turbine under different atmospheric stability conditions. Results will also show that the available atmospheric wind power is larger during daytime periods at the cost of an increased variance.
Lee, S. H.; Efendiev, Y.
2016-10-01
Three-phase flow in a reservoir model has been a major challenge in simulation studies due to slowly convergent iterations in Newton solution of nonlinear transport equations. In this paper, we examine the numerical characteristics of three-phase flow and propose a consistent, "C1-continuous discretization" (to be clarified later) of transport equations that ensures a convergent solution in finite difference approximation. First, we examine three-phase relative permeabilities that are critical in solving nonlinear transport equations. Three-phase relative permeabilities are difficult to measure in the laboratory, and they are often correlated with two-phase relative permeabilities (e.g., oil-gas and water-oil systems). Numerical convergence of non-linear transport equations entails that three-phase relative permeability correlations are a monotonically increasing function of the phase saturation and the consistency conditions of phase transitions are satisfied. The Modified Stone's Method II and the Linear Interpolation Method for three-phase relative permeability are closely examined for their mathematical properties. We show that the Linear Interpolation Method yields C1-continuous three-phase relative permeabilities for smooth solutions if the two phase relative permeabilities are monotonic and continuously differentiable. In the second part of the paper, we extend a Hybrid-Upwinding (HU) method of two-phase flow (Lee, Efendiev and Tchelepi, ADWR 82 (2015) 27-38) to three phase flow. In the HU method, the phase flux is divided into two parts based on the driving forces (in general, it can be divided into several parts): viscous and buoyancy. The viscous-driven and buoyancy-driven fluxes are upwinded differently. Specifically, the viscous flux, which is always co-current, is upwinded based on the direction of the total velocity. The pure buoyancy-induced flux is shown to be only dependent on saturation distributions and counter-current. In three-phase flow, the
Streamlined Modeling for Characterizing Spacecraft Anomalous Behavior
Klem, B.; Swann, D.
2011-09-01
Anomalous behavior of on-orbit spacecraft can often be detected using passive, remote sensors which measure electro-optical signatures that vary in time and spectral content. Analysts responsible for assessing spacecraft operational status and detecting detrimental anomalies using non-resolved imaging sensors are often presented with various sensing and identification issues. Modeling and measuring spacecraft self emission and reflected radiant intensity when the radiation patterns exhibit a time varying reflective glint superimposed on an underlying diffuse signal contribute to assessment of spacecraft behavior in two ways: (1) providing information on body component orientation and attitude; and, (2) detecting changes in surface material properties due to the space environment. Simple convex and cube-shaped spacecraft, designed to operate without protruding solar panel appendages, may require an enhanced level of preflight characterization to support interpretation of the various physical effects observed during on-orbit monitoring. This paper describes selected portions of the signature database generated using streamlined signature modeling and simulations of basic geometry shapes apparent to non-imaging sensors. With this database, summarization of key observable features for such shapes as spheres, cylinders, flat plates, cones, and cubes in specific spectral bands that include the visible, mid wave, and long wave infrared provide the analyst with input to the decision process algorithms contained in the overall sensing and identification architectures. The models typically utilize baseline materials such as Kapton, paints, aluminum surface end plates, and radiators, along with solar cell representations covering the cylindrical and side portions of the spacecraft. Multiple space and ground-based sensors are assumed to be located at key locations to describe the comprehensive multi-viewing aspect scenarios that can result in significant specular reflection
Animating streamlines with repeated asymmetric patterns for steady flow visualization
Yeh, Chih-Kuo; Liu, Zhanping; Lee, Tong-Yee
2012-01-01
Animation provides intuitive cueing for revealing essential spatial-temporal features of data in scientific visualization. This paper explores the design of Repeated Asymmetric Patterns (RAPs) in animating evenly-spaced color-mapped streamlines for dense accurate visualization of complex steady flows. We present a smooth cyclic variable-speed RAP animation model that performs velocity (magnitude) integral luminance transition on streamlines. This model is extended with inter-streamline synchronization in luminance varying along the tangential direction to emulate orthogonal advancing waves from a geometry-based flow representation, and then with evenly-spaced hue differing in the orthogonal direction to construct tangential flow streaks. To weave these two mutually dual sets of patterns, we propose an energy-decreasing strategy that adopts an iterative yet efficient procedure for determining the luminance phase and hue of each streamline in HSL color space. We also employ adaptive luminance interleaving in the direction perpendicular to the flow to increase the contrast between streamlines.
Yi-rang Yuan
2004-01-01
For compressible two-phase displacement problem,the modified upwind finite difference fractional steps schemes are put forward.Some techniques,such as calculus of variations,commutative law of multiplication of difference operators,decomposition of high order difference operators,the theory of prior estimates and techniques are used.Optimal order estimates in L 2 norm are derived for the error in the approximate solution.This method has already been applied to the numerical simulation of seawater intrusion and migration-accumulation of oil resources.
Advancements in Wind Energy Metrology – UPWIND 1A2.3
Angelou, Nikolas; Bingöl, Ferhat; Courtney, Michael
An overview of wind related metrology research made at Risø DTU over the period of the UPWIND project is given. A main part of the overview is devoted to development of the Lidar technology with several sub-chapters considering different topics of the research. Technical problems are not rare...... has a good chance of being implemented in the present revision of the IEC performance standard. Also, a turbulence normalization method has been tested but not found efficient enough for inclusion in the IEC standard. In relation to the coming IEC standard on performance verification with the use...
Flow and wakes in large wind farms. Final report for UpWind WP8
Barthelmie, R.J.; Frandsen, S.T.; Rathmann, O. (Risoe DTU (Denmark)); Hansen, K. (Technical Univ. of Denmark (DTU), Kgs. Lyngby (Denmark)); Politis, E.; Prospathopoulos, J. (CRES (Greece)); Schepers, J.G. (ECN, Petten (Netherlands)); Rados, K. (NTUA, Athens (Greece)); Cabezon, D. (CENER, Sarriguren (Spain)); Schlez, W.; Neubert, A.; Heath, M. (Garrad Hassan and Partners (Germany) (United Kingdom))
2011-02-15
This report summarises the research undertaken through the European Commission funded project UpWind Wp8:Flow. The objective of the work was to develop understanding of flow in large wind farms and to evaluate models of power losses due to wind turbine wakes focusing on complex terrain and offshore. A crosscutting activity was to improve and compare the performance of computational fluid dynamics models with wind farm models. The report contains 6 deliverable reports and guideline to wind farm wake analysis as appendices. (Author)
2D numerical comparison of trailing edge flaps - UpWind WP1B3
Buhl, Thomas; Andersen, Peter Bjørn; Barlas, T.K.
This report covers the investigations and comparisons of trailing edge flaps carried out by Delft and Risø. The work is a part of the W1B3 work package of the UpWind EU-project. This report covers only 2D test cases with simple control of the trailing edge flap with the objective of keeping CL......, and the performance of the flaps is investigated. The two different codes from Delft and Risø are compared in the mentioned cases....
Streamline topologies near a fixed wall using normal forms
Hartnack, Johan
1999-01-01
Streamline patterns and their bifurcations in two-dimensional incompressible viscous flow in the vicinity of a fixed wall have been investigated from a topological point of view by Bakker [11]. Bakker's work is revisited in a more general setting allowing a curvature of the fixed wall and a time...... dependence of the streamlines. The velocity field is expanded at a point on the wall, and the expansion coefficients are considered as bifurcation parameters. A series of nonlinear coordinate changes results in a much simplified system of differential equations for the streamlines (a normal form......) encapsulating all the features of the original system. From this, a complete description of bifurcations up to codimension three close to a simple linear degeneracy is obtained. Further, the case of a non-simple degeneracy is considered. Finally the effect of the Navier-Stokes equations on the local topology...
Vision and air flow combine to streamline flying honeybees.
Taylor, Gavin J; Luu, Tien; Ball, David; Srinivasan, Mandyam V
2013-01-01
Insects face the challenge of integrating multi-sensory information to control their flight. Here we study a 'streamlining' response in honeybees, whereby honeybees raise their abdomen to reduce drag. We find that this response, which was recently reported to be mediated by optic flow, is also strongly modulated by the presence of air flow simulating a head wind. The Johnston's organs in the antennae were found to play a role in the measurement of the air speed that is used to control the streamlining response. The response to a combination of visual motion and wind is complex and can be explained by a model that incorporates a non-linear combination of the two stimuli. The use of visual and mechanosensory cues increases the strength of the streamlining response when the stimuli are present concurrently. We propose this multisensory integration will make the response more robust to transient disturbances in either modality.
Streamline topologies near a fixed wall using normal forms
Hartnack, Johan
1998-01-01
Streamline patterns and their bifurcations in two-dimensional incompressible flow in the vicinity of a fixed wall has been investigated from a topological point of view by Bakker [Bifurcations in Flow Patterns. Kluwer Academic Publishers, 1991]. Bakkers work is revisited in a more general setting...... allowing curvature of the fixed wall and a time dependence of the streamlines. The velocity field is expanded at a point on the wall, and the expansion coefficients are considered as bifurcation parameters. A series of non-linear coordinate changes results in a much simplified system of differential...... of the Navier-Stokes equations on the local topology is considered....
Numerical Investigation of Thin Film Spreading Driven by Surfactant Using Upwind Schemes
E. Momoniat
2013-01-01
Full Text Available Numerical solutions of a coupled system of nonlinear partial differential equations modelling the effects of surfactant on the spreading of a thin film on a horizontal substrate are investigated. A CFL condition is obtained from a von Neumann stability analysis of a linearised system of equations. Numerical solutions obtained from a Roe upwind scheme with a third-order TVD Runge-Kutta approximation to the time derivative are compared to solutions obtained with a Roe-Sweby scheme coupled to a minmod limiter and a TVD approximation to the time derivative. Results from both of these schemes are compared to a Roe upwind scheme and a BDF approximation to the time derivative. In all three cases high-order approximations to the spatial derivatives are employed on the interior points of the spatial domain. The Roe-BDF scheme is shown to be an efficient numerical scheme for capturing sharp changes in gradient in the free surface profile and surfactant concentration. Numerical simulations of an initial exponential free surface profile coupled with initial surfactant concentrations for both exogenous and endogenous surfactants are considered.
Computer program calculates velocities and streamlines in turbomachines
Katsanis, T.
1968-01-01
Computer program calculates the velocity distribution and streamlines over widely separated blades of turbomachines. It gives the solutions of a two dimensional, subsonic, compressible nonviscous flow problem for a rotating or stationary circular cascade of blades on a blade-to-blade surface of revolution.
75 FR 4031 - Streamlining Hard-Copy Postage Statement Processing
2010-01-26
... From the Federal Register Online via the Government Publishing Office POSTAL SERVICE 39 CFR Part 111 Streamlining Hard-Copy Postage Statement Processing AGENCY: Postal Service\\TM\\. ACTION: Proposed rule. SUMMARY: The Postal Service\\TM\\ is proposing to revise Mailing Standards of the United States...
On stagnation points and streamline topology in vortex flows
Aref, Hassan; Brøns, Morten
1998-01-01
of the stagnation point in a flow produced by three vortices with sum of strengths zero is found. Using topological arguments the distinct streamline patterns for flow about three vortices are also determined. Partial results are given for two special sets of vortex strengths on the changes between these patterns...
On periodic water waves with Coriolis effects and isobaric streamlines
Matioc, Anca-Voichita
2012-01-01
In this paper we prove that solutions of the f-plane approximation for equatorial geophysical deep water waves, which have the property that the pressure is constant along the streamlines and do not possess stagnation points,are Gerstner-type waves. Furthermore, for waves traveling over a flat bed, we prove that there are only laminar flow solutions with these properties.
Streamline topology: Patterns in fluid flows and their bifurcations
Brøns, Morten
2007-01-01
Using dynamical systems theory, we consider structures such as vortices and separation in the streamline patterns of fluid flows. Bifurcation of patterns under variation of external parameters is studied using simplifying normal form transformations. Flows away from boundaries, flows close to fixed...
STREAMLINING THE POWERS AND DUTIES OF A RECEIVER ...
Mofasony
would contain the essential terms of the contract. ... shares of the company, ows the assets of the company, a proposition rightly ... Streamlining the Powers and Duties of a Receiver/ Manager and Liquidator in the Organization of ... Oman P., Corporate Governance and National Development, OCED Research Papers, No.
Merton, S.R. [Computational Physics Group, AWE, Aldermaston, Reading, Berkshire RG7 4PR (United Kingdom)], E-mail: simon.merton@awe.co.uk; Pain, C.C. [Computational Physics and Geophysics Group, Department of Earth Science and Engineering, Imperial College London, London SW7 2A7 (United Kingdom); Smedley-Stevenson, R.P. [Computational Physics Group, AWE, Aldermaston, Reading, Berkshire RG7 4PR (United Kingdom); Buchan, A.G.; Eaton, M.D. [Computational Physics and Geophysics Group, Department of Earth Science and Engineering, Imperial College London, London SW7 2A7 (United Kingdom)
2008-09-15
This paper describes the development of two optimal discontinuous finite element (FE) Riemann methods and their application to the one-speed Boltzmann transport equation in the steady-state. The proposed methods optimise the amount of dissipation applied in the streamline direction. This dissipation is applied within an element using a novel Riemann FE method, which is based on an analogy between control volume discretisation methods and finite element methods when integration by parts is applied to the transport terms. In one-dimension the optimal finite element solutions match the analytical solution exactly at each outlet node. Both schemes couple elements in space via a Riemann approach. The first of the two schemes is a Petrov-Galerkin (PG) method which introduces dissipation via the equation residual. The second scheme uses a streamline diffusion stabilisation term in the discretisation. These two methods provide a discontinuous Petrov-Galerkin (DPG) scheme that can stabilise an element across the full range of radiation regimes, obtaining robust solutions with suppressed oscillation. Three basis functions in angle of particle travel have been implemented in an optimal DPG Riemann solver, which include the P{sub N} (spherical harmonic), S{sub N} (discrete ordinate) and LW{sub N} (linear octahedral wavelet) angular expansions. These methods are applied to a series of demanding two-dimensional radiation transport problems.
Simulation of incompressible flows with heat and mass transfer using parallel finite element method
Jalal Abedi
2003-02-01
Full Text Available The stabilized finite element formulations based on the SUPG (Stream-line-Upwind/Petrov-Galerkin and PSPG (Pressure-Stabilization/Petrov-Galerkin methods are developed and applied to solve buoyancy-driven incompressible flows with heat and mass transfer. The SUPG stabilization term allows us to solve flow problems at high speeds (advection dominant flows and the PSPG term eliminates instabilities associated with the use of equal order interpolation functions for both pressure and velocity. The finite element formulations are implemented in parallel using MPI. In parallel computations, the finite element mesh is partitioned into contiguous subdomains using METIS, which are then assigned to individual processors. To ensure a balanced load, the number of elements assigned to each processor is approximately equal. To solve nonlinear systems in large-scale applications, we developed a matrix-free GMRES iterative solver. Here we totally eliminate a need to form any matrices, even at the element levels. To measure the accuracy of the method, we solve 2D and 3D example of natural convection flows at moderate to high Rayleigh numbers.
Guermond, Jean-Luc
2010-01-01
We revisit some results from M. L. Adams [Nu cl. Sci. Engrg., 137 (2001), pp. 298- 333]. Using functional analytic tools we prove that a necessary and sufficient condition for the standard upwind discontinuous Galerkin approximation to converge to the correct limit solution in the diffusive regime is that the approximation space contains a linear space of continuous functions, and the restrictions of the functions of this space to each mesh cell contain the linear polynomials. Furthermore, the discrete diffusion limit converges in the Sobolev space H1 to the continuous one if the boundary data is isotropic. With anisotropic boundary data, a boundary layer occurs, and convergence holds in the broken Sobolev space H with s < 1/2 only © 2010 Society for Industrial and Applied Mathematics.
Central-Upwind Schemes for Two-Layer Shallow Water Equations
Kurganov, Alexander
2009-01-01
We derive a second-order semidiscrete central-upwind scheme for one- and two-dimensional systems of two-layer shallow water equations. We prove that the presented scheme is well-balanced in the sense that stationary steady-state solutions are exactly preserved by the scheme and positivity preserving; that is, the depth of each fluid layer is guaranteed to be nonnegative. We also propose a new technique for the treatment of the nonconservative products describing the momentum exchange between the layers. The performance of the proposed method is illustrated on a number of numerical examples, in which we successfully capture (quasi) steady-state solutions and propagating interfaces. © 2009 Society for Industrial and Applied Mathematics.
Multi-dimensional upwind fluctuation splitting scheme with mesh adaption for hypersonic viscous flow
Wood, William Alfred, III
A multi-dimensional upwind fluctuation splitting scheme is developed and implemented for two dimensional and axisymmetric formulations of the Navier-Stokes equations on unstructured meshes. Key features of the scheme are the compact stencil, full upwinding, and non-linear discretization which allow for second-order accuracy with enforced positivity. Throughout, the fluctuation splitting scheme is compared to a current state-of-the-art finite volume approach, a second-order, dual mesh upwind flux difference splitting scheme (DMFDSFV), and is shown to produce more accurate results using fewer computer resources for a wide range of test cases. The scalar test cases include advected shear, circular advection, non-linear advection with coalescing shock and expansion fans, and advection-diffusion. For all scalar cases the fluctuation splitting scheme is more accurate, and the primary mechanism for the improved fluctuation splitting performance is shown to be the reduced production of artificial dissipation relative to DMFDSFV. The most significant scalar result is for combined advection-diffusion, where the present fluctuation splitting scheme is able to resolve the physical dissipation from the artificial dissipation on a much coarser mesh than DMFDSFV is able to, allowing order-of-magnitude reductions in solution time. Among the inviscid test cases the converging supersonic streams problem is notable in that the fluctuation splitting scheme exhibits superconvergent third-order spatial accuracy. For the inviscid cases of a supersonic diamond airfoil, supersonic slender cone, and incompressible circular bump the fluctuation splitting drag coefficient errors are typically half the DMFDSFV drag errors. However, for the incompressible inviscid sphere the fluctuation splitting drag error is larger than for DMFDSFV. A Blasius flat plate viscous validation case reveals a more accurate v-velocity profile for fluctuation splitting, and the reduced artificial dissipation
Yi-rang YUAN; Chang-feng LI; Cheng-shun YANG; Yu-ji HAN
2009-01-01
The research of the miscible oil and water displacement problem with moving boundary values is of great value to the history of oil-gas transport and accumulation in the basin evolution as well as to the rational evaluation in prospecting and exploiting oil-gas resources. The mathematical model can be described as a coupled system of nonlinear partial differential equations with moving boundary values. For the two-dimensional bounded region, the upwind finite difference schemes are proposed. Some techniques, such as the calculus of variations, the change of variables, and the theory of a priori estimates, are used. The optimal order l2-norm estimates are derived for the errors in the approximate solutions. The research is important both theoretically and practically for the model analysis in the field, the model numerical method, and the software development.
A set of strongly coupled, upwind algorithms for computing flows in chemical nonequilibrium
Molvik, Gregory A.; Merkle, Charles L.
1989-01-01
Two new algorithms have been developed to predict the flow of viscous, hypersonic, chemically reacting gases over three-dimensional bodies. Both take advantage of the benefits of upwind differencing, Total Variation Diminishing (TVD) techniques and of a finite-volume framework, but obtain their solution in two separate manners. The first algorithym is a time-marching scheme, and is generally used to obtain solutions in the subsonic portions of the flow field. The second algorithm is a much less expensive, space-marching scheme and can be used for the computation of the larger, supersonic portion of the flow field. Both codes compute their interface fluxes with a new temporal Riemann solver and the resulting schemes are made fully implicit including the chemical source terms.
A multi-dimensional kinetic-based upwind solver for the Euler equations
Eppard, W. M.; Grossman, B.
1993-01-01
A multidimensional kinetic fluctuation-splitting scheme has been developed for the Euler equations. The scheme is based on an N-scheme discretization of the Boltzmann equation at the kinetic level for triangulated Cartesian meshes with a diagonal-adaptive strategy. The resulting Euler scheme is a cell-vertex fluctuation-splitting scheme where fluctuations in the conserved-variable vector Q are obtained as moments of the fluctuation in the Maxwellian velocity distribution function at the kinetic level. Encouraging preliminary results have been obtained for perfect gases on Cartesian meshes with first-order spatial accuracy. The present approach represents an improvement to the well-established dimensionally-split upwind schemes.
An efficient and robust implicit operator for upwind point Gauss Seidel method
Kim, Joo Sung; Kwon, Oh Joon
2007-06-01
An efficient and robust implicit operator for the point Gauss-Seidel method is presented for solving the compressible Euler equations. The new implicit operator was derived by adding a scalar form of artificial dissipation to the upwind implicit side. The amount of artificial dissipation was locally adjusted using a weighting factor based on the solution gradient. For validation, the performance of the new implicit operator was compared in detail with that of several existing implicit operators which have been widely used for solving the flow equations. Numerical experiments showed that the stability and convergence characteristics of the new implicit operator are significantly better than those of other existing implicit operators for calculating flows ranging from subsonic to hypersonic speeds.
THE UPWIND FINITE DIFFERENCE METHOD FOR MOVING BOUNDARY VALUE PROBLEM OF COUPLED SYSTEM
Yuan Yirang
2011-01-01
Coupled system of multilayer dynamics of fluids in porous media is to describe the history of oil-gas transport and accumulation in basin evolution. It is of great value in rational evaluation of prospecting and exploiting oil-gas resources. The mathematical model can be described as a coupled system of nonlinear partial differential equations with moving boundary values. The upwind finite difference schemes applicable to parallel arith- metic are put forward and two-dimensional and three-dimensional schemes are used to form a complete set. Some techniques, such as change of variables, calculus of variations, multiplicative commutation rule of difference operators, decomposition of high order dif- ference operators and prior estimates, are adopted. The estimates in 12 norm are derived to determine the error in the approximate solution. This method was already applied to the numerical simulation of migration-accumulation of oil resources.
2010-11-30
... COMMISSION 47 CFR Part 73 Policies To Promote Rural Radio Service and To Streamline Allotment and Assignment... and to Streamline Allotment and Assignment Procedures, MB Docket No. 09-52, FCC 09-30, 24 FCC Rcd 5239... to Promote Rural Radio Service and to Streamline Allotment and Assignment Procedures (the ``Order...
Müller, K.; van Pinxteren, D.; Plewka, A.; Svrcina, B.; Kramberger, H.; Hofmann, D.; Bächmann, K.; Herrmann, H.
An extensive set of gaseous and particulate organic compounds was quantified before an orographic cloud passage at the upwind site of the research region in Thüringer Wald. Samples were collected with two different time resolutions, 2 h for gaseous species and spray absorber samples and the whole cloud event duration to determine the concentrations of ketones, aldehydes, monocarboxylic acids, dicarboxylic acids (DCA), hydrocarbons, biogenic sugars and alcohols in both the gas and particle phase. The measurement of different groups of organic compounds delivered size-segregated concentrations at the upwind site of a cloud experiment. The size distribution of DCA showed a peak in the mass-rich impactor stage 3 (0.42-1.2 μm). The concentrations of DCA from the filters, the impactor foils as well as the spray absorber samples decreased with increasing C-number. The time resolved measurements revealed an increasing mixing ratio from night time to midday for carboxylic and DCA, and related carbonyl compounds. The biogenic compounds xylitol (up to 103 ng m -3), levoglucosan (up to 62 ng m -3) and pinonaldehyde (up to 34 ng m -3) were the compounds found in highest concentrations in the particle phase beside the oxalate (up to 104 ng m -3). The organic trace gases with the highest mixing ratios identified were formaldehyde (up to 1.47 ppbv), acetaldehyde (up to 0.84 ppbv) and acetone (up to 0.65 ppbv), acetic acid (up to 0.43 ppbv) and formic acid (up to 0.41 ppbv).
Loh, Ching Y.; Jorgenson, Philip C. E.
2007-01-01
A time-accurate, upwind, finite volume method for computing compressible flows on unstructured grids is presented. The method is second order accurate in space and time and yields high resolution in the presence of discontinuities. For efficiency, the Roe approximate Riemann solver with an entropy correction is employed. In the basic Euler/Navier-Stokes scheme, many concepts of high order upwind schemes are adopted: the surface flux integrals are carefully treated, a Cauchy-Kowalewski time-stepping scheme is used in the time-marching stage, and a multidimensional limiter is applied in the reconstruction stage. However even with these up-to-date improvements, the basic upwind scheme is still plagued by the so-called "pathological behaviors," e.g., the carbuncle phenomenon, the expansion shock, etc. A solution to these limitations is presented which uses a very simple dissipation model while still preserving second order accuracy. This scheme is referred to as the enhanced time-accurate upwind (ETAU) scheme in this paper. The unstructured grid capability renders flexibility for use in complex geometry; and the present ETAU Euler/Navier-Stokes scheme is capable of handling a broad spectrum of flow regimes from high supersonic to subsonic at very low Mach number, appropriate for both CFD (computational fluid dynamics) and CAA (computational aeroacoustics). Numerous examples are included to demonstrate the robustness of the methods.
Barlas, A.; Van Kuik, G.A.M.
2009-01-01
A newly developed comprehensive aeroelastic model is used to investigate active flap concepts on the Upwind 5MW reference wind turbine. The model is specially designed to facilitate distributed control concepts and advanced controller design. Different concepts of centralized and distributed control
Barlas, A.; van Kuik, G.A.M.
2009-01-01
A newly developed comprehensive aeroelastic model is used to investigate active flap concepts on the Upwind 5MW reference wind turbine. The model is specially designed to facilitate distributed control concepts and advanced controller design. Different concepts of centralized and distributed control
Streamlining Throughput with the Implementation of a CT Coordinator.
Johnson, Kathleen; Johnson, Charles E; Porter, Linda; Bryant, Karen
2016-01-01
Imaging departments today are challenged with streamlining processes to keep up with advancements in healthcare, the increasing complexity of imaging studies and procedures, and bundling of charges for services rendered. Ordering providers are often required to get insurance pre-authorizations for imaging orders, and what is pre-authorized must be the study/procedure performed or reimbursement is not guaranteed. Insurance companies have inhibited radiologists from providing optimal service by placing restrictions on changing orders per radiologist protocol to best meet the individual needs of each patient. Many healthcare systems that are using a central scheduling model are losing money due to scans and procedures being inappropriately ordered and pre-authorized. Implementing a computed tomography (CT) coordinator can streamline throughput of imaging services in radiology departments. The CT improvement project described here used a Lean methodology Plan-Do-Check-Act (PDCA) approach to increase the effectiveness of an organization's ability to maximize process efficiency and revenue.
Streamline topologies and their bifurcations for mixed convective peristaltic flow
Z. Asghar
2015-09-01
Full Text Available In this work our focus is on streamlines patterns and their bifurcations for mixed convective peristaltic flow of Newtonian fluid with heat transfer. The flow is considered in a two dimensional symmetric channel and the governing equations are simplified under widely taken assumptions of large wavelength and low Reynolds number in a wave frame of reference. In order to study the streamlines patterns, a system of nonlinear autonomous differential equations are established and dynamical systems approach is used to discuss the local bifurcations and their topological changes. We have discussed all types of bifurcations and their topological changes are presented graphically. We found that the vortices contract along the vertical direction whereas they expand along horizontal direction. A global bifurcations diagram is used to summarize the bifurcations. The trapping and backward flow regions are mainly affected by increasing Grashof number and constant heat source parameter in such a way that trapping region increases whereas backward flow region shrinks.
Implementation science in the real world: a streamlined model.
Knapp, Herschel; Anaya, Henry D
2012-01-01
The process of quality improvement may involve enhancing or revising existing practices or the introduction of a novel element. Principles of Implementation Science provide key theories to guide these processes, however, such theories tend to be highly technical in nature and do not provide pragmatic nor streamlined approaches to real-world implementation. This paper presents a concisely comprehensive six step theory-based Implementation Science model that we have successfully used to launch more than two-dozen self-sustaining implementations. In addition, we provide an abbreviated case study in which we used our streamlined theoretical model to successfully guide the development and implementation of an HIV testing/linkage to care campaign in homeless shelter settings in Los Angeles County.
Energy of Unmanned Aerial Vehicle (UAV Windmill (theory, streamlined airflow
L. I. Grechikhin
2010-01-01
Full Text Available A windmill theory as an open power system is resolved in the paper. The paper presents a mechanism of a frontal resistance and a thrust load of the operating windmill which is based on occurrence of an active environmental component and formulates the conditions under which any minimum resistance and maximum thrust load are realized. An algorithm and software for calculation of windmill streamlining pattern are developed in the paper. The calculation results are given the paper.
Zephyr: an internet-based process to streamline engineering
Alford, F A; Cavitt, R E; Jordan, C W; Mauvais, M J; Niven, W A; Taylor, J M; Taylor, S S; Vickers, D L; Warren, F E; Weaver, R L
1998-07-01
Lawrence Livermore National Laboratory (LLNL) is implementing an Internet-based process pilot called 'Zephyr' to streamline engineering and commerce using the internet. Major benefits have accrued by using Zephyr in facilitating industrial collaboration, speeding the engineering development cycle, reducing procurement time, and lowering overall costs. Programs at LLNL are potentializing the efficiencies introduced since implementing Zephyr. Zephyr"s pilot functionality is undergoing full integration with Business Systems, Finance, and Vendors to support major programs at the Laboratory.
Zephyr: A secure Internet process to streamline engineering
Jordan, C.W.; Niven, W.A.; Cavitt, R.E. [and others
1998-05-12
Lawrence Livermore National Laboratory (LLNL) is implementing an Internet-based process pilot called `Zephyr` to streamline engineering and commerce using the Internet. Major benefits have accrued by using Zephyr in facilitating industrial collaboration, speeding the engineering development cycle, reducing procurement time, and lowering overall costs. Programs at LLNL are potentializing the efficiencies introduced since implementing Zephyr. Zephyr`s pilot functionality is undergoing full integration with Business Systems, Finance, and Vendors to support major programs at the Laboratory.
Streamlining CubeSat Solar Panel Fabrication Processes
Sandberg, Ariel; Smith, Timothy
2016-01-01
A critical facet of CubeSat fabrication is solar panel characterization and assembly. Though capable of producing flight quality solar subsystems, traditional methods of solar panel fabrication contain intrinsic inefficiencies and inconsistencies that compromise the subsystem’s overall reliability. Taking Michigan Exploration Laboratory’s (MXL) heritage solar panel procedures as a case study, this investigation sought to streamline the solar panel fabrication process to increase its yield, co...
Streamline segment scaling behavior in a turbulent wavy channel flow
Rubbert, A.; Hennig, F.; Klaas, M.; Pitsch, H.; Schröder, W.; Peters, N.
2017-02-01
A turbulent flow in a wavy channel was investigated by tomographic particle-image velocimetry measurements and direct numerical simulations. To analyze the turbulent structures and their scaling behavior in a flow undergoing favorable and adverse pressure gradients, the streamline segmentation method proposed by Wang (J Fluid Mech 648:183-203, 2010) was employed. This method yields joint statistical information about velocity fluctuations and length scale distributions of non-overlapping structures within the flow. In particular, the joint statistical properties are notably influenced by the pressure distribution. Previous findings from flat channel flows and synthetic turbulence simulations concerning the normalized segment length distribution could be reproduced and therefore appear to be largely universal. However, the mean streamline segment length of accelerating and decelerating segments varies within one wavelength typically elongating segments of the type which corresponds to the local mean flow. Furthermore, the local pressure gradient was found to significantly impact local joint streamline segmentation statistics as a main influence on their inherent asymmetry.
Dividing Streamline Formation Channel Confluences by Physical Modeling
Minarni Nur Trilita
2010-02-01
Full Text Available Confluence channels are often found in open channel network system and is the most important element. The incoming flow from the branch channel to the main cause various forms and cause vortex flow. Phenomenon can cause erosion of the side wall of the channel, the bed channel scour and sedimentation in the downstream confluence channel. To control these problems needed research into the current width of the branch channel. The incoming flow from the branch channel to the main channel flow bounded by a line distributors (dividing streamline. In this paper, the wide dividing streamline observed in the laboratory using a physical model of two open channels, a square that formed an angle of 30º. Observations were made with a variety of flow coming from each channel. The results obtained in the laboratory observation that the width of dividing streamline flow is influenced by the discharge ratio between the channel branch with the main channel. While the results of a comparison with previous studies showing that the observation in the laboratory is smaller than the results of previous research.
Reduced energy consumption by using streamlined gating systems
Seren Skov-Hansen; Niels Skat Tiedje
2008-01-01
In foundries a lot of effort is done to minimize energy consumption in the production to reduce costs and hence increase the competitiveness. At the same time the foundries must live up to the increased demands for high quality castings.Traditional gating systems are known for a straight tapered down runner, a well base and 90° bends in the runner system. Previous work has shown that the traditional way of designing gating systems creates high inconsistency in flow patterns during filling. In the streamlined gating systems there are no sharp changes in direction and a large effort is done to confine and control the flow of the molten metal during mould filling. The main objective in the work presented here is to use the principles of the streamlined gating systems to reduce the weight of the gating system relative to the traditional layouts. By reducing the weight of gating system and thereby improving yield, the amount of molten iron needed is also reduced, hence reducing the energy consumption for melting.Experiments in real production lines have proven that it is possible to achieve a reduction in the poured weight by using the streamlined gating systems. In a layout for casting of three valve housings in a vertically parted mould the weight of the gating system was reduced by 1.1 kg changing from the traditional layouts to the streamlined gating systems. This weight reduction corresponds in this case to a 20% weight reduction for the gating system. Using streamlined gating systems with fan gates to give a beneficial heat distribution in the castings may be an efficient tool to eliminate the need for heat treatment. In the experiments the change in gating system from the traditional layout to the streamlined layout removed the need for heat treatment. This obviously means a huge energy saving in the foundry. The energy consumption for heat treatment of iron has been found to be 0.489 kWh/kg. The valve housing in the experiments weighs 3 kg so when the need for
Application of Central Upwind Scheme for Solving Special Relativistic Hydrodynamic Equations.
Muhammad Yousaf
Full Text Available The accurate modeling of various features in high energy astrophysical scenarios requires the solution of the Einstein equations together with those of special relativistic hydrodynamics (SRHD. Such models are more complicated than the non-relativistic ones due to the nonlinear relations between the conserved and state variables. A high-resolution shock-capturing central upwind scheme is implemented to solve the given set of equations. The proposed technique uses the precise information of local propagation speeds to avoid the excessive numerical diffusion. The second order accuracy of the scheme is obtained with the use of MUSCL-type initial reconstruction and Runge-Kutta time stepping method. After a discussion of the equations solved and of the techniques employed, a series of one and two-dimensional test problems are carried out. To validate the method and assess its accuracy, the staggered central and the kinetic flux-vector splitting schemes are also applied to the same model. The scheme is robust and efficient. Its results are comparable to those obtained from the sophisticated algorithms, even in the case of highly relativistic two-dimensional test problems.
Incompressible Turbulent Flow Simulation Using the κ-ɛ Model and Upwind Schemes
V. G. Ferreira
2007-01-01
Full Text Available In the computation of turbulent flows via turbulence modeling, the treatment of the convective terms is a key issue. In the present work, we present a numerical technique for simulating two-dimensional incompressible turbulent flows. In particular, the performance of the high Reynolds κ-ɛ model and a new high-order upwind scheme (adaptative QUICKEST by Kaibara et al. (2005 is assessed for 2D confined and free-surface incompressible turbulent flows. The model equations are solved with the fractional-step projection method in primitive variables. Solutions are obtained by using an adaptation of the front tracking GENSMAC (Tomé and McKee (1994 methodology for calculating fluid flows at high Reynolds numbers. The calculations are performed by using the 2D version of the Freeflow simulation system (Castello et al. (2000. A specific way of implementing wall functions is also tested and assessed. The numerical procedure is tested by solving three fluid flow problems, namely, turbulent flow over a backward-facing step, turbulent boundary layer over a flat plate under zero-pressure gradients, and a turbulent free jet impinging onto a flat surface. The numerical method is then applied to solve the flow of a horizontal jet penetrating a quiescent fluid from an entry port beneath the free surface.
A Five-Parameter Wind Field Estimation Method Based on Spherical Upwind Lidar Measurements
Kapp, S.; Kühn, M.
2014-12-01
Turbine mounted scanning lidar systems of focussed continuous-wave type are taken into consideration to sense approaching wind fields. The quality of wind information depends on the lidar technology itself but also substantially on the scanning technique and reconstruction algorithm. In this paper a five-parameter wind field model comprising mean wind speed, vertical and horizontal linear shear and homogeneous direction angles is introduced. A corresponding parameter estimation method is developed based on the assumption of upwind lidar measurements scanned over spherical segments. As a main advantage of this method all relevant parameters, in terms of wind turbine control, can be provided. Moreover, the ability to distinguish between shear and skew potentially increases the quality of the resulting feedforward pitch angles when compared to three-parameter methods. It is shown that minimal three measurements, each in turn from two independent directions are necessary for the application of the algorithm, whereas simpler measurements, each taken from only one direction, are not sufficient.
A central-upwind scheme with artificial viscosity for shallow-water flows in channels
Hernandez-Duenas, Gerardo; Beljadid, Abdelaziz
2016-10-01
We develop a new high-resolution, non-oscillatory semi-discrete central-upwind scheme with artificial viscosity for shallow-water flows in channels with arbitrary geometry and variable topography. The artificial viscosity, proposed as an alternative to nonlinear limiters, allows us to use high-resolution reconstructions at a low computational cost. The scheme recognizes steady states at rest when a delicate balance between the source terms and flux gradients occurs. This balance in irregular geometries is more complex than that taking place in channels with vertical walls. A suitable technique is applied by properly taking into account the effects induced by the geometry. Incorporating the contributions of the artificial viscosity and an appropriate time step restriction, the scheme preserves the positivity of the water's depth. A description of the proposed scheme, its main properties as well as the proofs of well-balance and the positivity of the scheme are provided. Our numerical experiments confirm stability, well-balance, positivity-preserving properties and high resolution of the proposed method. Comparisons of numerical solutions obtained with the proposed scheme and experimental data are conducted, showing a good agreement. This scheme can be applied to shallow-water flows in channels with complex geometry and variable bed topography.
Comparison of upwind and downwind operation of the NREL Phase VI Experiment
Larwood, S. M.; Chow, R.
2016-09-01
Wind tunnel data are presented comparing upwind versus downwind operation of the National Renewable Energy Laboratory's Phase VI wind turbine. Power was not reduced as expected with downwind operation, which may be attributed to inboard three-dimensional effects. Average flap bending loads were reduced with downwind coning and compared well with prediction. Blade fatigue loads were increased with downwind operation; however, fatigue was mitigated with an aerodynamic tower shroud (fairing). The shroud needs to remain aligned with the freestream, demonstrated by an increase in fatigue loads from a 10° error in shroud alignment. Pressure data were acquired of the tower wake at the rotor location with and without the shroud installed. The bare-tower wake data compared well with previously published work. The shroud wake data at 10° error in alignment showed velocity reduction and turbulence approaching the bare tower values. Downwind operation, with an aligning tower shroud, should be considered for future designs given the load benefits of downwind coning.
An upwind vertex centred Finite Volume solver for Lagrangian solid dynamics
Aguirre, Miquel; Gil, Antonio J.; Bonet, Javier; Lee, Chun Hean
2015-11-01
A vertex centred Jameson-Schmidt-Turkel (JST) finite volume algorithm was recently introduced by the authors (Aguirre et al., 2014 [1]) in the context of fast solid isothermal dynamics. The spatial discretisation scheme was constructed upon a Lagrangian two-field mixed (linear momentum and the deformation gradient) formulation presented as a system of conservation laws [2-4]. In this paper, the formulation is further enhanced by introducing a novel upwind vertex centred finite volume algorithm with three key novelties. First, a conservation law for the volume map is incorporated into the existing two-field system to extend the range of applications towards the incompressibility limit (Gil et al., 2014 [5]). Second, the use of a linearised Riemann solver and reconstruction limiters is derived for the stabilisation of the scheme together with an efficient edge-based implementation. Third, the treatment of thermo-mechanical processes through a Mie-Grüneisen equation of state is incorporated in the proposed formulation. For completeness, the study of the eigenvalue structure of the resulting system of conservation laws is carried out to demonstrate hyperbolicity and obtain the correct time step bounds for non-isothermal processes. A series of numerical examples are presented in order to assess the robustness of the proposed methodology. The overall scheme shows excellent behaviour in shock and bending dominated nearly incompressible scenarios without spurious pressure oscillations, yielding second order of convergence for both velocities and stresses.
Paardekooper, S.-J.
2017-08-01
We present a new method for numerical hydrodynamics which uses a multidimensional generalization of the Roe solver and operates on an unstructured triangular mesh. The main advantage over traditional methods based on Riemann solvers, which commonly use one-dimensional flux estimates as building blocks for a multidimensional integration, is its inherently multidimensional nature, and as a consequence its ability to recognize multidimensional stationary states that are not hydrostatic. A second novelty is the focus on graphics processing units (GPUs). By tailoring the algorithms specifically to GPUs, we are able to get speedups of 100-250 compared to a desktop machine. We compare the multidimensional upwind scheme to a traditional, dimensionally split implementation of the Roe solver on several test problems, and we find that the new method significantly outperforms the Roe solver in almost all cases. This comes with increased computational costs per time-step, which makes the new method approximately a factor of 2 slower than a dimensionally split scheme acting on a structured grid.
Xin Wen; Shi Jin
2008-01-01
We study the L1-error estimates for the upwind scheme to the linear advection equations with a piecewise constant coefficients modeling linear waves crossing interfaces.Here the interface condition is immersed into the upwind scheme.We prove that,for initial data with a bounded variation,the numerical solution of the immersed interface upwind scheme converges in L1-norm to the differential equation with the corresponding interface condition.We derive the one-halfth order L1-error bounds with explicit coefficients following a technique used in [25].We also use some inequalities on binomial coefficients proved in a consecutive paper[32].
Streamlining digital signal processing a tricks of the trade guidebook
2012-01-01
Streamlining Digital Signal Processing, Second Edition, presents recent advances in DSP that simplify or increase the computational speed of common signal processing operations and provides practical, real-world tips and tricks not covered in conventional DSP textbooks. It offers new implementations of digital filter design, spectrum analysis, signal generation, high-speed function approximation, and various other DSP functions. It provides:Great tips, tricks of the trade, secrets, practical shortcuts, and clever engineering solutions from seasoned signal processing professionalsAn assortment.
Streamlined library programming how to improve services and cut costs
Porter-Reynolds, Daisy
2014-01-01
In their roles as community centers, public libraries offer many innovative and appealing programs; but under current budget cuts, library resources are stretched thin. With slashed budgets and limited staff hours, what can libraries do to best serve their publics? This how-to guide provides strategies for streamlining library programming in public libraries while simultaneously maintaining-or even improving-quality delivery. The wide variety of principles and techniques described can be applied on a selective basis to libraries of all sizes. Based upon the author's own extensive experience as
A streamlined ribosome profiling protocol for the characterization of microorganisms
Latif, Haythem; Szubin, Richard; Tan, Justin
2015-01-01
in the microbial research community. Here we present a streamlined ribosome profiling protocol with reduced barriers to entry for microbial characterization studies. Our approach provides simplified alternatives during harvest, lysis, and recovery of monosomes and also eliminates several time-consuming steps......Ribosome profiling is a powerful tool for characterizing in vivo protein translation at the genome scale, with multiple applications ranging from detailed molecular mechanisms to systems-level predictive modeling. Though highly effective, this intricate technique has yet to become widely used...
High-Order Semi-Discrete Central-Upwind Schemes for Multi-Dimensional Hamilton-Jacobi Equations
Bryson, Steve; Levy, Doron; Biegel, Bryan (Technical Monitor)
2002-01-01
We present the first fifth order, semi-discrete central upwind method for approximating solutions of multi-dimensional Hamilton-Jacobi equations. Unlike most of the commonly used high order upwind schemes, our scheme is formulated as a Godunov-type scheme. The scheme is based on the fluxes of Kurganov-Tadmor and Kurganov-Tadmor-Petrova, and is derived for an arbitrary number of space dimensions. A theorem establishing the monotonicity of these fluxes is provided. The spacial discretization is based on a weighted essentially non-oscillatory reconstruction of the derivative. The accuracy and stability properties of our scheme are demonstrated in a variety of examples. A comparison between our method and other fifth-order schemes for Hamilton-Jacobi equations shows that our method exhibits smaller errors without any increase in the complexity of the computations.
Eco-friendly streamlined process for sporopollenin exine capsule extraction
Mundargi, Raghavendra C.; Potroz, Michael G.; Park, Jae Hyeon; Seo, Jeongeun; Tan, Ee-Lin; Lee, Jae Ho; Cho, Nam-Joon
2016-01-01
Sporopollenin exine capsules (SECs) extracted from Lycopodium clavatum spores are an attractive biomaterial possessing a highly robust structure suitable for microencapsulation strategies. Despite several decades of research into SEC extraction methods, the protocols commonly used for L. clavatum still entail processing with both alkaline and acidolysis steps at temperatures up to 180 °C and lasting up to 7 days. Herein, we demonstrate a significantly streamlined processing regimen, which indicates that much lower temperatures and processing durations can be used without alkaline lysis. By employing CHN elemental analysis, scanning electron microscopy (SEM), confocal laser scanning microscopy (CLSM), and dynamic image particle analysis (DIPA), the optimum conditions for L. clavatum SEC processing were determined to include 30 hours acidolysis at 70 °C without alkaline lysis. Extending these findings to proof-of-concept encapsulation studies, we further demonstrate that our SECs are able to achieve a loading of 0.170 ± 0.01 g BSA per 1 g SECs by vacuum-assisted loading. Taken together, our streamlined processing method and corresponding characterization of SECs provides important insights for the development of applications including drug delivery, cosmetics, personal care products, and foods.
Analysis of Jupiter's Oval BA: A Streamlined Approach
Sussman, Michael G.; Chanover, Nancy J.; Simon-Miller, Amy A.; Vasavada, Ashwin R.; Beebe, Reta F.
2010-01-01
We present a novel method of constructing streamlines to derive wind speeds within jovian vortices and demonstrate its application to Oval BA for 2001 pre-reddened Cassini flyby data, 2007 post-reddened New Horizons flyby data, and 1998 Galileo data of precursor Oval DE. Our method, while automated, attempts to combine the advantages of both automated and manual cloud tracking methods. The southern maximum wind speed of Oval BA does not show significant changes between these data sets to within our measurement uncertainty. The northern maximum dries appear to have increased in strength during this time interval, tvhich likely correlates with the oval's return to a symmetric shape. We demonstrate how the use of closed streamlines can provide measurements of vorticity averaged over the encircled area with no a priori assumptions concerning oval shape. We find increased averaged interior vorticity between pre- and post-reddened Oval BA, with the precursor Oval DE occupying a middle value of vorticity between these two.
Stratified Flow Past a Hill: Dividing Streamline Concept Revisited
Leo, Laura S.; Thompson, Michael Y.; Di Sabatino, Silvana; Fernando, Harindra J. S.
2016-06-01
The Sheppard formula (Q J R Meteorol Soc 82:528-529, 1956) for the dividing streamline height H_s assumes a uniform velocity U_∞ and a constant buoyancy frequency N for the approach flow towards a mountain of height h, and takes the form H_s/h=( {1-F} ) , where F=U_{∞}/Nh. We extend this solution to a logarithmic approach-velocity profile with constant N. An analytical solution is obtained for H_s/h in terms of Lambert-W functions, which also suggests alternative scaling for H_s/h. A `modified' logarithmic velocity profile is proposed for stably stratified atmospheric boundary-layer flows. A field experiment designed to observe H_s is described, which utilized instrumentation from the spring field campaign of the Mountain Terrain Atmospheric Modeling and Observations (MATERHORN) Program. Multiple releases of smoke at F≈ 0.3-0.4 support the new formulation, notwithstanding the limited success of experiments due to logistical constraints. No dividing streamline is discerned for F≈ 10, since, if present, it is too close to the foothill. Flow separation and vortex shedding is observed in this case. The proposed modified logarithmic profile is in reasonable agreement with experimental observations.
Assessment of RANS to predict flows with large streamline curvature
Yin, J. L.; Wang, D. Z.; Cheng, H.; Gu, W. G.
2013-12-01
In order to provide a guideline for choosing turbulence models in computation of complex flows with large streamline curvature, this paper presents a comprehensive comparison investigation of different RANS models widely used in engineering to check each model's sensibility on the streamline curvature. First, different models including standard k-ε, Realizable k-ε, Renormalization-group (RNG) k-ε model, Shear-stress transport k-ω model and non-linear eddy-viscosity model v2-f model are tested to simulated the flow in a 2D U-bend which has the standard bench mark available. The comparisons in terms of non-dimensional velocity and turbulent kinetic energy show that large differences exist among the results calculated by various models. To further validate the capability to predict flows with secondary flows, the involved models are tested in a 3D 90° bend flow. Also, the velocities are compared. As a summary, the advantages and disadvantages of each model are analysed and guidelines for choice of turbulence model are presented.
Analytis, G.Th. [Paul Scherrer Institute (PSI), Villigen (Switzerland)
1995-09-01
As is well-known, both TRAC-BF1 and TRAC-PF are using the first upwind scheme when finite-differencing the phasic momentum equations. In contrast, RELAP5 uses the second upwind which is less diffusive. In this work, we shall assess the differences between the two schemes with our modified version of RELAP5/MOD3 by analyzing some transients of interest. These will include the LOFT LP-LB-1 and LOBI small break LOCA (SB-LOCA) BL34 tests, and a commercial PWR 200% hypothetical large break LOCA (LB-LOCA). In particular, we shall show that for some of these transients, the employment of the first upwind scheme results in significantly different code predictions than the ones obtained when the second upwind scheme is used.
Aggelidis, Costas Nickolaos
2007-12-01
nip. Two-dimensional modeling of calendering elasto-visco-plastic materials with a slight modification of the discrete elasto-viscous split stress, independent velocity gradient interpolation, streamline upwind Petrov-Galerkin (DEVSS-G/SUPG) method, predicts distributions of the departure of the current material state in the nip from the elastic stress-free state in a warped material space and of stresses in the calendering nip.
Corsini, A.; Rispoli, F.; Santoriello, A.; Tezduyar, T. E.
2006-09-01
Recent advances in turbulence modeling brought more and more sophisticated turbulence closures (e.g. k-ɛ, k-ɛ - v 2- f, Second Moment Closures), where the governing equations for the model parameters involve advection, diffusion and reaction terms. Numerical instabilities can be generated by the dominant advection or reaction terms. Classical stabilized formulations such as the Streamline Upwind/Petrov Galerkin (SUPG) formulation (Brook and Hughes, comput methods Appl Mech Eng 32:199 255, 1982; Hughes and Tezduyar, comput methods Appl Mech Eng 45: 217 284, 1984) are very well suited for preventing the numerical instabilities generated by the dominant advection terms. A different stabilization however is needed for instabilities due to the dominant reaction terms. An additional stabilization term, called the diffusion for reaction-dominated (DRD) term, was introduced by Tezduyar and Park (comput methods Appl Mech Eng 59:307 325, 1986) for that purpose and improves the SUPG performance. In recent years a new class of variational multi-scale (VMS) stabilization (Hughes, comput methods Appl Mech Eng 127:387 401, 1995) has been introduced, and this approach, in principle, can deal with advection diffusion reaction equations. However, it was pointed out in Hanke (comput methods Appl Mech Eng 191:2925 2947) that this class of methods also need some improvement in the presence of high reaction rates. In this work we show the benefits of using the DRD operator to enhance the core stabilization techniques such as the SUPG and VMS formulations. We also propose a new operator called the DRDJ (DRD with the local variation jump) term, targeting the reduction of numerical oscillations in the presence of both high reaction rates and sharp solution gradients. The methods are evaluated in the context of two stabilized methods: the classical SUPG formulation and a recently-developed VMS formulation called the V-SGS (Corsini et al. comput methods Appl Mech Eng 194:4797 4823, 2005
Study on increasing calculation precision and convergence speed of streamline strip element method
彭艳; 刘宏民
2004-01-01
The calculation precision and convergence speed of streamline strip element method are increased by using the method whose initial value of the exit lateral displacement is determined with strip element variation method, and the accurate tension lateral distribution model is adopted based on the original third power spline function streamline strip element method. The basic theory of the strip element method is developed. The calculated results by the improved streamline strip element method and the original streamline strip element method are compared with the measured results, showing that the calculated results of the improved method are in good agreement with the measured results.
Hybrid Upwinding for Two-Phase Flow in Heterogeneous Porous Media with Buoyancy and Capillarity
Hamon, F. P.; Mallison, B.; Tchelepi, H.
2016-12-01
In subsurface flow simulation, efficient discretization schemes for the partial differential equations governing multiphase flow and transport are critical. For highly heterogeneous porous media, the temporal discretization of choice is often the unconditionally stable fully implicit (backward-Euler) method. In this scheme, the simultaneous update of all the degrees of freedom requires solving large algebraic nonlinear systems at each time step using Newton's method. This is computationally expensive, especially in the presence of strong capillary effects driven by abrupt changes in porosity and permeability between different rock types. Therefore, discretization schemes that reduce the simulation cost by improving the nonlinear convergence rate are highly desirable. To speed up nonlinear convergence, we present an efficient fully implicit finite-volume scheme for immiscible two-phase flow in the presence of strong capillary forces. In this scheme, the discrete viscous, buoyancy, and capillary spatial terms are evaluated separately based on physical considerations. We build on previous work on Implicit Hybrid Upwinding (IHU) by using the upstream saturations with respect to the total velocity to compute the relative permeabilities in the viscous term, and by determining the directionality of the buoyancy term based on the phase density differences. The capillary numerical flux is decomposed into a rock- and geometry-dependent transmissibility factor, a nonlinear capillary diffusion coefficient, and an approximation of the saturation gradient. Combining the viscous, buoyancy, and capillary terms, we obtain a numerical flux that is consistent, bounded, differentiable, and monotone for homogeneous one-dimensional flow. The proposed scheme also accounts for spatially discontinuous capillary pressure functions. Specifically, at the interface between two rock types, the numerical scheme accurately honors the entry pressure condition by solving a local nonlinear problem
Topology of streamlines and vorticity contours for two - dimensional flows
Andersen, Morten
Considering a coordinate-free formulation of helical symmetry rather than more traditional definitions based on coordinates, we discuss basic properties of helical vector fields and compare results from the literature. For inviscid flow where a velocity field is generated by a sum of helical vortex...... generated by a helical vortex filament in an ideal fluid. The classical expression for the stream function obtained by Hardin (Phys. Fluids 25, 1982) contains an infinite sum of modified Bessel functions. Using the approach by Okulov (Russ. J. Eng. Thermophys. 5, 1995) we obtain a closed-form approximation...... by a point vortex above a wall in inviscid fluid. There is no reason to a priori expect equivalent results of the three vortex definitions. However, the study is mainly motivated by the findings of Kudela & Malecha (Fluid Dyn. Res. 41, 2009) who find good agreement between the vorticity and streamlines...
A Streamlined Strategy for Biohydrogen Production with an Alkaliphilic Bacterium
Elias, Dwayne A [ORNL; Wall, Judy D. [University of Missouri; Mormile, Dr. Melanie R. [Missouri University of Science and Technology; Begemann, Matthew B [University of Wisconsin, Madison
2012-01-01
Biofuels are anticipated to enable a shift from fossil fuels for renewable transportation and manufacturing fuels, with biohydrogen considered attractive since it could offer the largest reduction of global carbon budgets. Currently, biohydrogen production remains inefficient and heavily fossil fuel-dependent. However, bacteria using alkali-treated biomass could streamline biofuel production while reducing costs and fossil fuel needs. An alkaliphilic bacterium, Halanaerobium strain sapolanicus, is described that is capable of biohydrogen production at levels rivaling neutrophilic strains, but at pH 11 and hypersaline conditions. H. sapolanicus ferments a variety of 5- and 6- carbon sugars derived from hemicellulose and cellulose including cellobiose, and forms the end products hydrogen and acetate. Further, it can also produce biohydrogen from switchgrass and straw pretreated at temperatures far lower than any previously reported and in solutions compatible with growth. Hence, this bacterium can potentially increase the efficiency and efficacy of biohydrogen production from renewable biomass resources.
The Cassini Solstice Mission: Streamlining Operations by Sequencing with PIEs
Vandermey, Nancy; Alonge, Eleanor K.; Magee, Kari; Heventhal, William
2014-01-01
The Cassini Solstice Mission (CSM) is the second extended mission phase of the highly successful Cassini/Huygens mission to Saturn. Conducted at a much-reduced funding level, operations for the CSM have been streamlined and simplified significantly. Integration of the science timeline, which involves allocating observation time in a balanced manner to each of the five different science disciplines (with representatives from the twelve different science instruments), has long been a labor-intensive endeavor. Lessons learned from the prime mission (2004-2008) and first extended mission (Equinox mission, 2008-2010) were utilized to design a new process involving PIEs (Pre-Integrated Events) to ensure the highest priority observations for each discipline could be accomplished despite reduced work force and overall simplification of processes. Discipline-level PIE lists were managed by the Science Planning team and graphically mapped to aid timeline deconfliction meetings prior to assigning discrete segments of time to the various disciplines. Periapse segments are generally discipline-focused, with the exception of a handful of PIEs. In addition to all PIEs being documented in a spreadsheet, allocated out-of-discipline PIEs were entered into the Cassini Information Management System (CIMS) well in advance of timeline integration. The disciplines were then free to work the rest of the timeline internally, without the need for frequent interaction, debate, and negotiation with representatives from other disciplines. As a result, the number of integration meetings has been cut back extensively, freeing up workforce. The sequence implementation process was streamlined as well, combining two previous processes (and teams) into one. The new Sequence Implementation Process (SIP) schedules 22 weeks to build each 10-week-long sequence, and only 3 sequence processes overlap. This differs significantly from prime mission during which 5-week-long sequences were built in 24 weeks
Streamlined analysis of lactose-free dairy products.
Morlock, Gertrud E; Morlock, Lauritz P; Lemo, Carot
2014-01-10
Functional food for lactose-intolerant consumers and its global prevalence has created a large market for commercially available lactose-free food products. The simplest approach for detection and quantitation of lactose in lactose-free dairy products was developed. A one-step sample preparation was employed and the resulting 10% sample solution was directly subjected to the chromatographic system. LODs down to 0.04 mg/L were obtained for dairy products by application volumes up to 250 μL on a rectangular start zone, which is the lowest LOD reported in matrix so far. The highly matrix-robust, streamlined approach was demonstrated for a broad range of dairy products, even with high fat and protein contents. The mean recovery rate for 11 types of dairy products spiked at the strictest lactose content discussed (0.01%) was 90.5±10.5% (n=11). The mean repeatability for 11 dairy products spiked at the 0.01% level was 1.3±1.0% (n=11). It is the simplest approach with regard to sample preparation at low running costs (0.3 Euro or 0.4 USD/analysis) and fast analysis time (3 min/analysis). It enabled an efficient product screening, and at the same time, the quantitation of lactose in relevant samples. This streamlined analysis is highly attractive to the field of food safety and quality control of lactose-free dairy products, for which a limit value for lactose is expected soon in the EU. This methodological concept can be transferred to other challenging fields.
Streamlined bioreactor-based production of human cartilage tissues.
Tonnarelli, B; Santoro, R; Adelaide Asnaghi, M; Wendt, D
2016-05-27
Engineered tissue grafts have been manufactured using methods based predominantly on traditional labour-intensive manual benchtop techniques. These methods impart significant regulatory and economic challenges, hindering the successful translation of engineered tissue products to the clinic. Alternatively, bioreactor-based production systems have the potential to overcome such limitations. In this work, we present an innovative manufacturing approach to engineer cartilage tissue within a single bioreactor system, starting from freshly isolated human primary chondrocytes, through the generation of cartilaginous tissue grafts. The limited number of primary chondrocytes that can be isolated from a small clinically-sized cartilage biopsy could be seeded and extensively expanded directly within a 3D scaffold in our perfusion bioreactor (5.4 ± 0.9 doublings in 2 weeks), bypassing conventional 2D expansion in flasks. Chondrocytes expanded in 3D scaffolds better maintained a chondrogenic phenotype than chondrocytes expanded on plastic flasks (collagen type II mRNA, 18-fold; Sox-9, 11-fold). After this "3D expansion" phase, bioreactor culture conditions were changed to subsequently support chondrogenic differentiation for two weeks. Engineered tissues based on 3D-expanded chondrocytes were more cartilaginous than tissues generated from chondrocytes previously expanded in flasks. We then demonstrated that this streamlined bioreactor-based process could be adapted to effectively generate up-scaled cartilage grafts in a size with clinical relevance (50 mm diameter). Streamlined and robust tissue engineering processes, as the one described here, may be key for the future manufacturing of grafts for clinical applications, as they facilitate the establishment of compact and closed bioreactor-based production systems, with minimal automation requirements, lower operating costs, and increased compliance to regulatory guidelines.
The Cassini Solstice Mission: Streamlining Operations by Sequencing with PIEs
Vandermey, Nancy; Alonge, Eleanor K.; Magee, Kari; Heventhal, William
2014-01-01
The Cassini Solstice Mission (CSM) is the second extended mission phase of the highly successful Cassini/Huygens mission to Saturn. Conducted at a much-reduced funding level, operations for the CSM have been streamlined and simplified significantly. Integration of the science timeline, which involves allocating observation time in a balanced manner to each of the five different science disciplines (with representatives from the twelve different science instruments), has long been a labor-intensive endeavor. Lessons learned from the prime mission (2004-2008) and first extended mission (Equinox mission, 2008-2010) were utilized to design a new process involving PIEs (Pre-Integrated Events) to ensure the highest priority observations for each discipline could be accomplished despite reduced work force and overall simplification of processes. Discipline-level PIE lists were managed by the Science Planning team and graphically mapped to aid timeline deconfliction meetings prior to assigning discrete segments of time to the various disciplines. Periapse segments are generally discipline-focused, with the exception of a handful of PIEs. In addition to all PIEs being documented in a spreadsheet, allocated out-of-discipline PIEs were entered into the Cassini Information Management System (CIMS) well in advance of timeline integration. The disciplines were then free to work the rest of the timeline internally, without the need for frequent interaction, debate, and negotiation with representatives from other disciplines. As a result, the number of integration meetings has been cut back extensively, freeing up workforce. The sequence implementation process was streamlined as well, combining two previous processes (and teams) into one. The new Sequence Implementation Process (SIP) schedules 22 weeks to build each 10-week-long sequence, and only 3 sequence processes overlap. This differs significantly from prime mission during which 5-week-long sequences were built in 24 weeks
2012-05-31
... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Policies To Promote Rural Radio Service and To Streamline Allotment and Assignment... policies to promote rural radio service and to streamline allotment and assignment procedures. This notice...
2012-12-04
... COMMISSION 47 CFR Part 73 Policies To Promote Rural Radio Service and To Streamline Allotment and Assignment... policies to promote rural radio service and to streamline allotment and assignment procedures. This notice...: Control Number: 3060-0031. Title: Application for Consent to Assignment of Broadcast Station Construction...
A Vocabulary Approach to Partial Streamline Matching and Exploratory Flow Visualization.
Tao, Jun; Wang, Chaoli; Shene, Ching-Kuang; Shaw, Raymond A
2016-05-01
Measuring the similarity of integral curves is fundamental to many important flow data analysis and visualization tasks such as feature detection, pattern querying, streamline clustering, and hierarchical exploration. In this paper, we introduce FlowString, a novel vocabulary approach that extracts shape invariant features from streamlines and utilizes a string-based method for exploratory streamline analysis and visualization. Our solution first resamples streamlines by considering their local feature scales. We then classify resampled points along streamlines based on the shape similarity around their local neighborhoods. We encode each streamline into a string of well-selected shape characters, from which we construct meaningful words for querying and retrieval. A unique feature of our approach is that it captures intrinsic streamline similarity that is invariant under translation, rotation and scaling. We design an intuitive interface and user interactions to support flexible querying, allowing exact and approximate searches for partial streamline matching. Users can perform queries at either the character level or the word level, and define their own characters or words conveniently for customized search. We demonstrate the effectiveness of FlowString with several flow field data sets of different sizes and characteristics. We also extend FlowString to handle multiple data sets and perform an empirical expert evaluation to confirm the usefulness of this approach.
Advancements in Wind Energy Metrology - UPWIND 1A2.3
Pedersen, Troels F.; Wagner, R.
2011-02-15
An overview of wind related metrology research made at Risoe DTU over the period of the UPWIND project is given. A main part of the overview is devoted to development of the Lidar technology with several sub-chapters considering different topics of the research. Technical problems are not rare for this new technology, and testing against a traditional met mast have shown to be efficient for gaining confidence with the ground based Lidar technology and for trust in accuracy of measurements. In principle, Lidar measurements could be traceable through the fundamental measurement principles, but at this stage of development it is not found feasible. Instead, traceability is secured through comparison with met masts that are traceable through wind tunnel calibrations of cup anemometers. The ground based Lidar measurement principle works almost acceptable in flat terrain. In complex terrain and close to woods the measurement volume is disturbed because the flow is no longer horizontally homogeneous. These conditions require special attention and correction methods. Due to the large measurement volume, ground based Lidars perform a spatial averaging which has the effect of a low pass filter on turbulence measurements. Theory and measurements seem to be in good agreement. Lidar measurements from a rotating spinner have been performed. The analysis show good perspectives for scanning the incoming wind, which may lead to better controlled wind turbines. Lidars have also been used to scan the wake of wind turbines. These measurements document the meandering wake pattern. The second part of the overview considers power performance measurements. A new investigation on the influence of wind shear points to a revision of the definition of a power curve. A new measurement method has been developed which has a good chance of being implemented in the present revision of the IEC performance standard. Also, a turbulence normalization method has been tested but not found efficient
Introduction to COFFE: The Next-Generation HPCMP CREATE-AV CFD Solver
Glasby, Ryan S.; Erwin, J. Taylor; Stefanski, Douglas L.; Allmaras, Steven R.; Galbraith, Marshall C.; Anderson, W. Kyle; Nichols, Robert H.
2016-01-01
HPCMP CREATE-AV Conservative Field Finite Element (COFFE) is a modular, extensible, robust numerical solver for the Navier-Stokes equations that invokes modularity and extensibility from its first principles. COFFE implores a flexible, class-based hierarchy that provides a modular approach consisting of discretization, physics, parallelization, and linear algebra components. These components are developed with modern software engineering principles to ensure ease of uptake from a user's or developer's perspective. The Streamwise Upwind/Petrov-Galerkin (SU/PG) method is utilized to discretize the compressible Reynolds-Averaged Navier-Stokes (RANS) equations tightly coupled with a variety of turbulence models. The mathematics and the philosophy of the methodology that makes up COFFE are presented.
Hu, L H; Peng, W; Huo, R
2008-01-15
In case of a tunnel fire, toxic gas and smoke particles released are the most fatal contaminations. It is important to supply fresh air from the upwind side to provide a clean and safe environment upstream from the fire source for people evacuation. Thus, the critical longitudinal wind velocity for arresting fire induced upwind gas and smoke dispersion is a key criteria for tunnel safety design. Former studies and thus, the models built for estimating the critical wind velocity are all arbitrarily assuming that the fire takes place at the centre of the tunnel. However, in many real cases in road tunnels, the fire originates near the sidewall. The critical velocity of a near-wall fire should be different with that of a free-standing central fire due to their different plume entrainment process. Theoretical analysis and CFD simulation were performed in this paper to estimate the critical velocity for the fire near the sidewall. Results showed that when fire originates near the sidewall, it needs larger critical velocity to arrest the upwind gas and smoke dispersion than when fire at the centre. The ratio of critical velocity of a near-wall fire to that of a central fire was ideally estimated to be 1.26 by theoretical analysis. Results by CFD modelling showed that the ratio decreased with the increase of the fire size till near to unity. The ratio by CFD modelling was about 1.18 for a 500kW small fire, being near to and a bit lower than the theoretically estimated value of 1.26. However, the former models, including those of Thomas (1958, 1968), Dangizer and Kenndey (1982), Oka and Atkinson (1995), Wu and Barker (2000) and Kunsch (1999, 2002), underestimated the critical velocity needed for a fire near the tunnel sidewall.
Sánchez Burillo, Guillermo; Beguería, Santiago; Latorre, Borja; Burguete, Javier
2014-05-01
Debris flows, snow and rock avalanches, mud and earth flows are often modeled by means of a particular realization of the so called shallow water equations (SWE). Indeed, a number of simulation models have been already developed [1], [2], [3], [4], [5], [6], [7]. Debris flow equations differ from shallow water equations in two main aspects. These are (a) strong bed gradient and (b) rheology friction terms that differ from the traditional SWE. A systematic analysis of the numerical solution of the hyperbolic system of equations rising from the shallow water equations with different rheological laws has not been done. Despite great efforts have been done to deal with friction expressions common in hydraulics (such as Manning friction), landslide rheologies are characterized by more complicated expressions that may deal to unphysical solutions if not treated carefully. In this work, a software that solves the time evolution of sliding masses over complex bed configurations is presented. The set of non- linear equations is treated by means of a first order upwind explicit scheme, and the friction contribution to the dynamics is treated with a suited numerical scheme [8]. In addition, the software incorporates various rheological models to accommodate for different flow types, such as the Voellmy frictional model [9] for rock and debris avalanches, or the Herschley-Bulkley model for debris and mud flows. The aim of this contribution is to release this code as a free, open source tool for the simulation of mass movements, and to encourage the scientific community to make use of it. The code uses as input data the friction coefficients and two input files: the topography of the bed and the initial (pre-failure) position of the sliding mass. In addition, another file with the final (post-event) position of the sliding mass, if desired, can be introduced to be compared with the simulation obtained result. If the deposited mass is given, an error estimation is computed by
YUAN Yirang; LIANG Dong; RUI Hongxing
2006-01-01
Numerical simulation and analysis of seawater intrusion is the mathematical basis for modern environmental science. Its mathematical model is the nonlinear coupled system of partial differential equations with initial-boundary problems. For a generic case of a three-dimensional bounded region, the modified method of upwind with finite difference fractional steps procedure is put forward. Optimal order estimates in L2 norm are derived for the error in the approximation solution. The present method has been successfully used in predicting the consequences of seawater intrusion and protection projects.
Bryson, Steve
2010-10-11
We introduce a new second-order central-upwind scheme for the Saint-Venant system of shallow water equations on triangular grids. We prove that the scheme both preserves "lake at rest" steady states and guarantees the positivity of the computed fluid depth. Moreover, it can be applied to models with discontinuous bottom topography and irregular channel widths. We demonstrate these features of the new scheme, as well as its high resolution and robustness in a number of numerical examples. © EDP Sciences, SMAI, 2010.
YUAN; Yiran(袁益让)
2002-01-01
For combinatorial system of multilayer dynamics of fluids in porous media, the second order and first order upwind finite difference fractional steps schemes applicable to parallel arithmetic are put forward and two-dimensional and three-dimensional schemes are used to form a complete set. Some techniques,such as implicit-explicit difference scheme, calculus of variations, multiplicative commutation rule of difference operators, decomposition of high order difference operators and prior estimates, are adopted. Optimal order estimates in L2 norm are derived to determine the error in the second order approximate solution. This method has already been applied to the numerical simulation of migration-accumulation of oil resources.
Yirang YUAN
2006-01-01
For nonlinear coupled system of multilayer dynamics of fluids in porous media, the second order and first order upwind finite difference fractional steps schemes applicable to parallel arithmetic are put forward, and two-dimensional and three-dimensional schemes are used to form a complete set. Some techniques, such as calculus of variations, multiplicative commutation rule of difference operators, decomposition of high order difference operators and prior estimates, are adopted. Optimal order estimates in L2 norm are derived to determine the error in the second order approximate solution.This method has already been applied to the numerical simulation of migration-accumulation of oil resources.
Hamon, F. P.; Mallison, B.; Tchelepi, H.
2015-12-01
The systems of algebraic equations arising from implicit (backward-Euler) finite-volume discretization of the conservation laws governing multiphase flow in porous media are quite challenging for nonlinear solvers. In the presence of counter-current flow due to buoyancy, the coupling between flow (pressure) and transport (saturations) is often the cause of nonlinear problems when single-point Phase-Potential Upwinding (PPU) is used. To overcome such convergence problems in practice, the time step is reduced and Newton's method is restarted from the solution at the previous converged time step. Here, we generalize the work of Lee, Efendiev and Tchelepi [Advances in Water Resources, 2015] to propose an Implicit Hybrid Upwinding (IHU) scheme for coupled flow and transport. In the pure transport problem, we show that the numerical flux obtained with IHU is differentiable, monotone and consistent for two and three-phase flow. For coupled flow and transport, we prove saturation physical bounds as well as the existence of a solution to our scheme. Challenging two- and three-phase heterogeneous multi-dimensional numerical tests confirm that the new scheme is non-oscillatory and convergent, and illustrate the superior convergence rate of our IHU-based Newton solver for large time steps.
Unexpectedly Streamlined Mitochondrial Genome of the Euglenozoan Euglena gracilis.
Dobáková, Eva; Flegontov, Pavel; Skalický, Tomáš; Lukeš, Julius
2015-11-20
In this study, we describe the mitochondrial genome of the excavate flagellate Euglena gracilis. Its gene complement is reduced as compared with the well-studied sister groups Diplonemea and Kinetoplastea. We have identified seven protein-coding genes: Three subunits of respiratory complex I (nad1, nad4, and nad5), one subunit of complex III (cob), and three subunits of complex IV (cox1, cox2, and a highly divergent cox3). Moreover, fragments of ribosomal RNA genes have also been identified. Genes encoding subunits of complex V, ribosomal proteins and tRNAs were missing, and are likely located in the nuclear genome. Although mitochondrial genomes of diplonemids and kinetoplastids possess the most complex RNA processing machineries known, including trans-splicing and editing of the uridine insertion/deletion type, respectively, our transcriptomic data suggest their total absence in E. gracilis. This finding supports a scenario in which the complex mitochondrial processing machineries of both sister groups evolved relatively late in evolution from a streamlined genome and transcriptome of their common predecessor.
VISMASHUP: streamlining the creation of custom visualization applications
Ahrens, James P [Los Alamos National Laboratory; Santos, Emanuele [UNIV OF UTAH; Lins, Lauro [UNIV OF UTAH; Freire, Juliana [UNIV OF UTAH; Silva, Cl' audio T [UNIV OF UTAH
2010-01-01
Visualization is essential for understanding the increasing volumes of digital data. However, the process required to create insightful visualizations is involved and time consuming. Although several visualization tools are available, including tools with sophisticated visual interfaces, they are out of reach for users who have little or no knowledge of visualization techniques and/or who do not have programming expertise. In this paper, we propose VISMASHUP, a new framework for streamlining the creation of customized visualization applications. Because these applications can be customized for very specific tasks, they can hide much of the complexity in a visualization specification and make it easier for users to explore visualizations by manipulating a small set of parameters. We describe the framework and how it supports the various tasks a designer needs to carry out to develop an application, from mining and exploring a set of visualization specifications (pipelines), to the creation of simplified views of the pipelines, and the automatic generation of the application and its interface. We also describe the implementation of the system and demonstrate its use in two real application scenarios.
The Single Crew Module Concept a Streamlined Way to Explore
Chambliss, Joe
2012-01-01
Many concepts have been proposed for exploring space. In early 2010 presidential direction called for reconsidering the approach to address changes in exploration destinations, use of new technologies and development of new capabilities to support exploration of space. Considering the proposed new technology and capabilities that NASA was directed to pursue, the single crew module (SCM) concept for a more streamlined approach to the infrastructure and conduct of exploration missions was developed. The SCM concept combines many of the new promising technologies with a central concept of mission architectures that uses a single habitat module for all phases of an exploration mission. Integrating mission elements near Earth and fully fueling them prior to departure of the vicinity of Earth provides the capability of using the single habitat both in transit to an exploration destination and while exploring the destination. The concept employs the capability to return the habitat and interplanetary propulsion system to Earth vicinity so that those elements can be reused on subsequent exploration missions. This paper describes the SCM concept, and the advantages it provides to accomplish exploration objectives.
STUDY FOR STREAMLINE OF ARBITRARY SHAPED HOMOGENEOUS RESERVOIRS WITH IMPERMEABLE BARRIERS
YIN Hong-jun; FU Chun-quan; HE Ying-fu
2006-01-01
The steady-state flow mathematical model of arbitrary shaped homogeneous reservoirs with impermeable barrier is constructed in this paper. By using Boundary Element Method (BEM), the mathematical model is solved. And a streamline generating technique is presented. The figures of streamlines are plotted and analyzed considering the effect of complex boundary and impermeable barriers. Through analyzing, it indicates that the size, shape and orientation of impermeable barriers have various degree of influence on the streamlines. So, if there are impermeable barriers in reservoir according to the geological materials, the influence of impermeable barriers must be considered when adjusting flood pattern and injection strategy.
Stream-lined Gating Systems with Improved Yield - Dimensioning and Experimental Validation
Tiedje, Niels Skat; Skov-Hansen, Søren Peter
The paper describes how a stream-lined gating system where the melt is confined and controlled during filling can be designed. Commercial numerical modelling software has been used to compare the stream-lined design with a traditional gating system. These results are confirmed by experiments where...... the two types of lay-outs are cast in production. It is shown that flow in the stream-lined lay-out is well controlled and that the quality of the castings is as at least equal to that of castings produced with a traditional lay-out. Further, the yield is improved by 4 % relative to a traditional lay-out....
Streamlining of the RELAP5-3D Code
Mesina, George L; Hykes, Joshua; Guillen, Donna Post
2007-11-01
RELAP5-3D is widely used by the nuclear community to simulate general thermal hydraulic systems and has proven to be so versatile that the spectrum of transient two-phase problems that can be analyzed has increased substantially over time. To accommodate the many new types of problems that are analyzed by RELAP5-3D, both the physics and numerical methods of the code have been continuously improved. In the area of computational methods and mathematical techniques, many upgrades and improvements have been made decrease code run time and increase solution accuracy. These include vectorization, parallelization, use of improved equation solvers for thermal hydraulics and neutron kinetics, and incorporation of improved library utilities. In the area of applied nuclear engineering, expanded capabilities include boron and level tracking models, radiation/conduction enclosure model, feedwater heater and compressor components, fluids and corresponding correlations for modeling Generation IV reactor designs, and coupling to computational fluid dynamics solvers. Ongoing and proposed future developments include improvements to the two-phase pump model, conversion to FORTRAN 90, and coupling to more computer programs. This paper summarizes the general improvements made to RELAP5-3D, with an emphasis on streamlining the code infrastructure for improved maintenance and development. With all these past, present and planned developments, it is necessary to modify the code infrastructure to incorporate modifications in a consistent and maintainable manner. Modifying a complex code such as RELAP5-3D to incorporate new models, upgrade numerics, and optimize existing code becomes more difficult as the code grows larger. The difficulty of this as well as the chance of introducing errors is significantly reduced when the code is structured. To streamline the code into a structured program, a commercial restructuring tool, FOR_STRUCT, was applied to the RELAP5-3D source files. The
Streamline Integration using MPI-Hybrid Parallelism on a Large Multi-Core Architecture
Camp, David; Garth, Christoph; Childs, Hank; Pugmire, Dave; Joy, Kenneth I.
2010-11-01
Streamline computation in a very large vector field data set represents a significant challenge due to the non-local and datadependentnature of streamline integration. In this paper, we conduct a study of the performance characteristics of hybrid parallel programmingand execution as applied to streamline integration on a large, multicore platform. With multi-core processors now prevalent in clustersand supercomputers, there is a need to understand the impact of these hybrid systems in order to make the best implementation choice.We use two MPI-based distribution approaches based on established parallelization paradigms, parallelize-over-seeds and parallelize-overblocks,and present a novel MPI-hybrid algorithm for each approach to compute streamlines. Our findings indicate that the work sharing betweencores in the proposed MPI-hybrid parallel implementation results in much improved performance and consumes less communication andI/O bandwidth than a traditional, non-hybrid distributed implementation.
Changes in the adiabatic invariant and streamline chaos in confined incompressible Stokes flow
Vainshtein, D. L.; Vasiliev, A. A.; Neishtadt, A. I.
1996-03-01
The steady incompressible flow in a unit sphere introduced by Bajer and Moffatt [J. Fluid Mech. 212, 337 (1990)] is discussed. The velocity field of this flow differs by a small perturbation from an integrable field whose streamlines are almost all closed. The unperturbed flow has two stationary saddle points (poles of the sphere) and a two-dimensional separatrix passing through them. The entire interior of the unit sphere becomes the domain of streamline chaos for an arbitrarily small perturbation. This phenomenon is explained by the nonconservation of a certain adiabatic invariant that undergoes a jump when a streamline crosses a small neighborhood of the separatrix of the unperturbed flow. An asymptotic formula is obtained for the jump in the adiabatic invariant. The accumulation of such jumps in the course of repeated crossings of the separatrix results in the complete breaking of adiabatic invariance and streamline chaos.
Streamline integration using MPI-hybrid parallelism on a large multicore architecture.
Camp, David; Garth, Christoph; Childs, Hank; Pugmire, Dave; Joy, Kenneth I
2011-11-01
Streamline computation in a very large vector field data set represents a significant challenge due to the nonlocal and data-dependent nature of streamline integration. In this paper, we conduct a study of the performance characteristics of hybrid parallel programming and execution as applied to streamline integration on a large, multicore platform. With multicore processors now prevalent in clusters and supercomputers, there is a need to understand the impact of these hybrid systems in order to make the best implementation choice. We use two MPI-based distribution approaches based on established parallelization paradigms, parallelize over seeds and parallelize over blocks, and present a novel MPI-hybrid algorithm for each approach to compute streamlines. Our findings indicate that the work sharing between cores in the proposed MPI-hybrid parallel implementation results in much improved performance and consumes less communication and I/O bandwidth than a traditional, nonhybrid distributed implementation.
Streamlining genomes: toward the generation of simplified and stabilized microbial systems
Leprince, A.; Passel, van M.W.J.; Martins Dos Santos, V.A.P.
2012-01-01
At the junction between systems and synthetic biology, genome streamlining provides a solid foundation both for increased understanding of cellular circuitry, and for the tailoring of microbial chassis towards innovative biotechnological applications. Iterative genomic deletions (targeted and random
Streamlined, Inexpensive 3D Printing of the Brain and Skull.
Jason S Naftulin
Full Text Available Neuroimaging technologies such as Magnetic Resonance Imaging (MRI and Computed Tomography (CT collect three-dimensional data (3D that is typically viewed on two-dimensional (2D screens. Actual 3D models, however, allow interaction with real objects such as implantable electrode grids, potentially improving patient specific neurosurgical planning and personalized clinical education. Desktop 3D printers can now produce relatively inexpensive, good quality prints. We describe our process for reliably generating life-sized 3D brain prints from MRIs and 3D skull prints from CTs. We have integrated a standardized, primarily open-source process for 3D printing brains and skulls. We describe how to convert clinical neuroimaging Digital Imaging and Communications in Medicine (DICOM images to stereolithography (STL files, a common 3D object file format that can be sent to 3D printing services. We additionally share how to convert these STL files to machine instruction gcode files, for reliable in-house printing on desktop, open-source 3D printers. We have successfully printed over 19 patient brain hemispheres from 7 patients on two different open-source desktop 3D printers. Each brain hemisphere costs approximately $3-4 in consumable plastic filament as described, and the total process takes 14-17 hours, almost all of which is unsupervised (preprocessing = 4-6 hr; printing = 9-11 hr, post-processing = <30 min. Printing a matching portion of a skull costs $1-5 in consumable plastic filament and takes less than 14 hr, in total. We have developed a streamlined, cost-effective process for 3D printing brain and skull models. We surveyed healthcare providers and patients who confirmed that rapid-prototype patient specific 3D models may help interdisciplinary surgical planning and patient education. The methods we describe can be applied for other clinical, research, and educational purposes.
Streamlined, Inexpensive 3D Printing of the Brain and Skull.
Naftulin, Jason S; Kimchi, Eyal Y; Cash, Sydney S
2015-01-01
Neuroimaging technologies such as Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) collect three-dimensional data (3D) that is typically viewed on two-dimensional (2D) screens. Actual 3D models, however, allow interaction with real objects such as implantable electrode grids, potentially improving patient specific neurosurgical planning and personalized clinical education. Desktop 3D printers can now produce relatively inexpensive, good quality prints. We describe our process for reliably generating life-sized 3D brain prints from MRIs and 3D skull prints from CTs. We have integrated a standardized, primarily open-source process for 3D printing brains and skulls. We describe how to convert clinical neuroimaging Digital Imaging and Communications in Medicine (DICOM) images to stereolithography (STL) files, a common 3D object file format that can be sent to 3D printing services. We additionally share how to convert these STL files to machine instruction gcode files, for reliable in-house printing on desktop, open-source 3D printers. We have successfully printed over 19 patient brain hemispheres from 7 patients on two different open-source desktop 3D printers. Each brain hemisphere costs approximately $3-4 in consumable plastic filament as described, and the total process takes 14-17 hours, almost all of which is unsupervised (preprocessing = 4-6 hr; printing = 9-11 hr, post-processing = Printing a matching portion of a skull costs $1-5 in consumable plastic filament and takes less than 14 hr, in total. We have developed a streamlined, cost-effective process for 3D printing brain and skull models. We surveyed healthcare providers and patients who confirmed that rapid-prototype patient specific 3D models may help interdisciplinary surgical planning and patient education. The methods we describe can be applied for other clinical, research, and educational purposes.
A Method for Streamlining and Assessing Sound Velocity Profiles Based on Improved D-P Algorithm
Zhao, D.; WU, Z. Y.; Zhou, J.
2015-12-01
A multi-beam system transmits sound waves and receives the round-trip time of their reflection or scattering, and thus it is possible to determine the depth and coordinates of the detected targets using the sound velocity profile (SVP) based on Snell's Law. The SVP is determined by a device. Because of the high sampling rate of the modern device, the operational time of ray tracing and beam footprint reduction will increase, lowering the overall efficiency. To promote the timeliness of multi-beam surveys and data processing, redundant points in the original SVP must be screened out and at the same time, errors following the streamlining of the SVP must be evaluated and controlled. We presents a new streamlining and evaluation method based on the Maximum Offset of sound Velocity (MOV) algorithm. Based on measured SVP data, this method selects sound velocity data points by calculating the maximum distance to the sound-velocity-dimension based on an improved Douglas-Peucker Algorithm to streamline the SVP (Fig. 1). To evaluate whether the streamlined SVP meets the desired accuracy requirements, this method is divided into two parts: SVP streamlining, and an accuracy analysis of the multi-beam sounding data processing using the streamlined SVP. Therefore, the method is divided into two modules: the streamlining module and the evaluation module (Fig. 2). The streamlining module is used for streamlining the SVP. Its core is the MOV algorithm.To assess the accuracy of the streamlined SVP, we uses ray tracing and the percentage error analysis method to evaluate the accuracy of the sounding data both before and after streamlining the SVP (Fig. 3). By automatically optimizing the threshold, the reduction rate of sound velocity profile data can reach over 90% and the standard deviation percentage error of sounding data can be controlled to within 0.1% (Fig. 4). The optimized sound velocity profile data improved the operational efficiency of the multi-beam survey and data post
Department of pharmacy-initiated program for streamlining empirical antibiotic therapy.
Pastel, D A; Chang, S; Nessim, S; Shane, R; Morgan, M A
1992-07-01
The outcome of a department of pharmacy-initiated "streamlining" study designed to promote cost-conscious modifications of empirically selected antibiotic therapy is described. Two hundred forty-one evaluable adult patients started on restricted-use antibiotics at this university-affiliated community private teaching hospital were enrolled in a 9-week prospective streamlining study. Patients were alternately assigned to a Control (i.e., no pharmacist-initiated streamlining recommendations offered based on culture and susceptibility reports) or a Pharmacist Intervention group (i.e., pharmacist offers recommendations to streamline therapy). A statistically significant greater number of patients had their empiric antibiotic treatment courses modified to more appropriate antibiotic choices after receipt of culture and susceptibility reports among private prescribers in the Pharmacist Intervention group (83%) than in the Control group (38%) (p = .006). Additionally, pharmacists were overall successful in gaining prescriber acceptance for 64% of recommended changes of empiric antibiotic treatment courses before the receipt of culture and susceptibility reports (e.g., dose and/or frequency changes). There was no program effect observed with respect to improved physician response to microbiologic data that would allow streamlining empirical antibiotic choices in the Housestaff (i.e., medical or surgical residents), or infectious disease consultant prescriber groups. Projected overall annual cost savings that would be achieved as a result of continued efforts by pharmacists directed at streamlining empirical "restricted" antibiotic regimens is approximately +40,000.
Kou, Jisheng
2014-03-22
Discontinuous Galerkin methods with interior penalties and upwind schemes are applied to the original formulation modeling incompressible two-phase flow in porous media with the capillary pressure. The pressure equation is obtained by summing the discretized conservation equations of two phases. This treatment is very different from the conventional approaches, and its great merit is that the mass conservations hold for both phases instead of only one phase in the conventional schemes. By constructing a new continuous map and using the fixed-point theorem, we prove the global existence of discrete solutions under the proper conditions, and furthermore, we obtain a priori hp error estimates of the pressures in L 2 (H 1) and the saturations in L ∞(L 2) and L 2 (H 1). © 2014 Wiley Periodicals, Inc.
Managing Written Directives: A Software Solution to Streamline Workflow.
Wagner, Robert H; Savir-Baruch, Bital; Gabriel, Medhat Sam; Halama, James; Bova, Davide
2017-03-09
retrieve active and prior completed directives at any stage of completion and at time. Conclusion: A software solution for the management of WDs streamlines and structures the workflow in the department. Implementation of this solution saves time, centralizes the information for all staff to share and decreases any confusion surrounding the creation, completion, filing, and retrieval of WDs.
Hongxing RUI; Chunjia BI
2008-01-01
In this paper we construct an upwind finite volume element scheme based on the Crouzeix-Raviart nonconforming element for nonselfadjoint elliptic problems. These problems often appear in dealing with flow in porous media. We establish the optimal order H1-norm error estimate. We also give the uniform convergence under minimal elliptic regularity assumption.
A STREAMLINE-BASED PREDICTIVE MODEL FOR ENHANCED-OIL-RECOVERY POTENTIALITY
HOU Jian; ZHANG Shun-kang; DU Qing-jun; LI Yu-bin
2008-01-01
A pseudo-three-dimensional model of potentiality prediction is proposed for enhanced oil recovery, based on the streamline method described in this article. The potential distribution of the flow through a porous medium under a complicated boundary condition is solved with the boundary element method. Furthermore, the method for tracing streamlines between injection wells and producing wells is presented. Based on the results, a numerical solution can be obtained by solving the seepage problem of the stream-tube with consideration of different methods of Enhanced Oil Recovery(EOR). The advantage of the method given in this article is that it can obtain dynamic calculation with different well patterns of any shape by easily considering different physicochemical phenomena having less calculation time and good stability. Based on the uniform theory basis-streamline method, different models, including CO2 miscible flooding, polymer flooding, alkaline/surfactant/polymer flooding and microbial flooding, are established in this article.
The length distribution of streamline segments in homogeneous isotropic decaying turbulence
Schaefer, P.; Gampert, M.; Peters, N.
2012-04-01
Based on the profile of the absolute value u of the velocity field ui along streamlines, the latter are partitioned into segments at their extreme points as proposed by Wang [J. Fluid Mech. 648, 183-203 (2010)], 10.1017/S0022112009993041. It is found that the boundaries of all streamline segments, i.e., points where the gradient projected in streamline direction ∂u/∂s vanishes, define a surface in space. This surface also contains all local extreme points of the scalar u-field, i.e., points where the gradient in all directions of the field of the absolute value of the velocity and thereby those of the turbulent kinetic energy (k = u2/2, where k is the instantaneous turbulent kinetic energy) vanishes. Such points also include stagnation points of the flow field, which are absolute minimum points of the turbulent kinetic energy. As local extreme points are the ending points of dissipation elements, an approach for space-filling geometries in turbulent scalar fields, such elements in the turbulent kinetic energy field also end and begin on the surface and the temporal evolution of dissipation elements and streamline segments are intimately related. Streamline segments by construction evolve both morphologically and topologically. A morphological evolution of a streamline segment corresponds to a continuous deformation when it is subject to stretching or compression and thus also implies a continuous evolution of the arclength l with time. Such an evolution does not change the number of the overall streamline segments and hence does not involve counting. On the other hand a topological evolution corresponds to either a cutting of a large segment into smaller ones or a connection of two smaller ones to form a larger segment. Such a process changes the number of segments and thus involves counting. This change of integer variables (i.e., counting) yields discrete jumps in the length of the streamline segment which are discontinuous in time. Following the terminology
Stable, streamlined and helical cavity formation by the impact of Leidenfrost spheres
Mansoor, Mohammad; Vakarelski, Ivan; Marston, Jeremy; Truscott, Tadd; Thoroddsen, Sigurdur
2016-11-01
This work reports results from an experimental study on the formation of stable-streamlined and helical cavity wakes following the free-surface impact of Leidenfrost spheres. The Leidenfrost effect encapsulates the sphere by a vapor layer to prevent any physical contact with the surrounding liquid. This phenomenon is essential for the pacification of acoustic rippling along the cavity interface to result in a stable-streamlined cavity wake. Such a streamlined configuration experiences drag coefficients an order of magnitude lower than those acting on room temperature spheres. A striking observation is the formation of helical cavities which occur for impact Reynolds numbers Re0 >= 1 . 4 ×105 and are characterized by multiple interfacial ridges, stemming from and rotating synchronously about an evident contact line around the sphere equator. This helical configuration has 40 - 55 % smaller overall force coefficients than those obtained in the formation of stable cavity wakes.
Using a 3-dimensional laser anemometer to determine mean streamline patterns in a turbulent flow
Orloff, K. L.; Snyder, P. K.
1984-01-01
The determination of mean streamline patterns by moving the test point in the direction of the measured velocity is shown to produce cumulative errors that are unacceptable. A two-dimensional algorithm that minimizes these errors is presented and is analytically validated using simple potential flows. The algorithm is extended to three-dimensional flows and is again validated analytically. Finally, as an example of a typical application of the algorithm, mean streamlines are measured in a complex, turbulent flow with a three-dimensional laser anemometer.
Streamline Patterns and their Bifurcations near a wall with Navier slip Boundary Conditions
Tophøj, Laust; Møller, Søren; Brøns, Morten
2006-01-01
We consider the two-dimensional topology of streamlines near a surface where the Navier slip boundary condition applies. Using transformations to bring the streamfunction in a simple normal form, we obtain bifurcation diagrams of streamline patterns under variation of one or two external parameters....... Topologically, these are identical with the ones previously found for no-slip surfaces. We use the theory to analyze the Stokes flow inside a circle, and show how it can be used to predict new bifurcation phenomena. ©2006 American Institute of Physics...
Analysis of Streamline Separation at Infinity Using Time-Discrete Markov Chains.
Reich, W; Scheuermann, G
2012-12-01
Existing methods for analyzing separation of streamlines are often restricted to a finite time or a local area. In our paper we introduce a new method that complements them by allowing an infinite-time-evaluation of steady planar vector fields. Our algorithm unifies combinatorial and probabilistic methods and introduces the concept of separation in time-discrete Markov-Chains. We compute particle distributions instead of the streamlines of single particles. We encode the flow into a map and then into a transition matrix for each time direction. Finally, we compare the results of our grid-independent algorithm to the popular Finite-Time-Lyapunov-Exponents and discuss the discrepancies.
An upwind, kinetic flux-vector splitting method for flows in chemical and thermal non-equilibrium
Eppard, W. M.; Grossman, B.
1993-01-01
We have developed new upwind kinetic difference schemes for flows with non-equilibrium thermodynamics and chemistry. These schemes are derived from the Boltzmann equation with the resulting Euler schemes developed as moments of the discretized Boltzmann scheme with a locally Maxwellian velocity distribution. Splitting the velocity distribution at the Boltzmann level is seen to result in a flux-split Euler scheme and is called Kinetic Flux Vector Splitting (KFVS). Extensions to flows with finite-rate chemistry and vibrational relaxation is accomplished utilizing nonequilibrium kinetic theory. Computational examples are presented comparing KFVS with the schemes of Van Leer and Roe for a quasi-one-dimensional flow through a supersonic diffuser, inviscid flow through two-dimensional inlet, and viscous flow over a cone at zero angle-of-attack. Calculations are also shown for the transonic flow over a bump in a channel and the transonic flow over an NACA 0012 airfoil. The results show that even though the KFVS scheme is a Riemann solver at the kinetic level, its behavior at the Euler level is more similar to the existing flux-vector splitting algorithms than to the flux-difference splitting scheme of Roe.
An upwind, kinetic flux-vector splitting method for flows in chemical and thermal non-equilibrium
Eppard, W. M.; Grossman, B.
1993-01-01
We have developed new upwind kinetic difference schemes for flows with non-equilibrium thermodynamics and chemistry. These schemes are derived from the Boltzmann equation with the resulting Euler schemes developed as moments of the discretized Boltzmann scheme with a locally Maxwellian velocity distribution. Splitting the velocity distribution at the Boltzmann level is seen to result in a flux-split Euler scheme and is called Kinetic Flux Vector Splitting (KFVS). Extensions to flows with finite-rate chemistry and vibrational relaxation is accomplished utilizing nonequilibrium kinetic theory. Computational examples are presented comparing KFVS with the schemes of Van Leer and Roe for a quasi-one-dimensional flow through a supersonic diffuser, inviscid flow through two-dimensional inlet, and viscous flow over a cone at zero angle-of-attack. Calculations are also shown for the transonic flow over a bump in a channel and the transonic flow over an NACA 0012 airfoil. The results show that even though the KFVS scheme is a Riemann solver at the kinetic level, its behavior at the Euler level is more similar to the existing flux-vector splitting algorithms than to the flux-difference splitting scheme of Roe.
Badrot-Nico, Fabiola; Brissaud, François; Guinot, Vincent
2007-09-01
A finite volume upwind numerical scheme for the solution of the linear advection equation in multiple dimensions on Cartesian grids is presented. The small-stencil, Modified Discontinuous Profile Method (MDPM) uses a sub-cell piecewise constant reconstruction and additional information at the cell interfaces, rather than a spatial extension of the stencil as in usual methods. This paper presents the MDPM profile reconstruction method in one dimension and its generalization and algorithm to two- and three-dimensional problems. The method is extended to the advection-diffusion equation in multiple dimensions. The MDPM is tested against the MUSCL scheme on two- and three-dimensional test cases. It is shown to give high-quality results for sharp gradients problems, although some scattering appears. For smooth gradients, extreme values are best preserved with the MDPM than with the MUSCL scheme, while the MDPM does not maintain the smoothness of the original shape as well as the MUSCL scheme. However the MDPM is proved to be more efficient on coarse grids in terms of error and CPU time, while on fine grids the MUSCL scheme provides a better accuracy at a lower CPU.
2011-07-19
... Assignment Procedures AGENCY: Federal Communications Commission. ACTION: Final rules; announcement of... Matter of Policies to Promote Rural Radio Service and to Streamline Allotment and Assignment Procedures... assignments (AM) over the current facility. Applications that are submitted to change an existing radio...
2010-03-04
... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Policies To Promote Rural Radio Service and To Streamline Allotment and Assignment Procedures AGENCY: Federal Communications Commission. ACTION: Proposed rule. SUMMARY: In this document, the...
2010-03-04
... COMMISSION 47 CFR Part 73 Policies To Promote Rural Radio Service and To Streamline Allotment and Assignment... suggested by commenters. First, the Commission will allow assignments or transfers within the four-year... modifications: (1) It will allow assignments or transfers of permits or licenses obtained using the Tribal...
2012-01-20
... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Policies To Promote Rural Radio Service and To Streamline Allotment and Assignment...-year prohibition on assignment or transfer (but will still be subject to a four-year prohibition on...
2011-03-16
... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Policies To Promote Rural Radio Service and To Streamline Allotment and Assignment Procedures AGENCY: Federal Communications Commission. ACTION: Proposed rule. SUMMARY: In this document, the...
A. M. Treguier
2007-07-01
Full Text Available An eddying global model is used to study the characteristics of the Antarctic Circumpolar Current (ACC in a streamline-following framework. In the upper layers, the meridional circulation across streamlines agrees with the theoretical view: an equatorward mean flow partially cancelled by a poleward eddy mass flux. The same calculation in a zonal average gives a completely different view and underestimates the eddy effects. Two model simulations, in which the buoyancy forcing above the ACC changes from positive to negative, suggest that the relationship between the residual meridional circulation and the surface buoyancy flux is not as straightforward as assumed by some recent theoretical studies: even the sign of the residual circulation cannot be inferred from the buoyancy forcing. Heat and salt transports by the time-mean flow are important even in the streamline framework. Streamline-averaged, two-dimensional models cannot account quantitatively for the complex three-dimensional structure of the ACC. Heat and salt are balanced in the ACC, the model drift being small, but the nonlinearity of the equation of state cannot be ignored in the density balance.
Mathematical Model of Hydrodynamic Torque Converter and Analytic Description of Streamline
LIU Shiping; QUAN Long
2009-01-01
The mathematical model of a 3-element centripetal-turbine hydrodynamic torque converter and analytic description of fluid flow inside the hydrodynamic torque converter are investigated. A new torus coordinate system is proposed so as to quantitatively describe fluid movement inside the hydrodynamic torque converter. The particle movement inside the hydrodynamic torque converter is decomposed into meridional component movement and torus component movement, and a universal meridional streamline equation is derived. According to the relationship between the converter wheel velocity polygon and its blade angle, a torus streamline differential equation is established. The universal meridional streamline equation is approximated with square polynomials. The approximation error curve is given and the percentage error is not greater than 0.86%. Considered as a function of polar angle, the blade angle cotangent of each converter wheel varies linearly with polar angle. By using integral calculus, torus streamline equations are obtained. As a result, the problem of difficult flow description of the hydrodynamic torque converter is solved and a new analytic research system is established.
Micro-Doppler Effect of Extended Streamlined Targets Based on Sliding Scattering Centre Model
Bo Tang
2016-06-01
Full Text Available The scattering center of extended streamlined targets can slide when the direction of radiation is changed. The sliding scattering center has influence on the micro-Doppler effect of micro-motion of the extended streamlined target. This paper focused on the micro-Doppler of the extended streamlined target for the bistatic radar. Based on the analysis, the analytical expressions of the micro-Doppler of coning motion with sliding scattering center model were given for bistatic radar. And the results were validated by the simulated results of the scattering field based on the full-wave method of the electromagnetic computation. The results showed that the sliding of the scattering center can make the micro-Doppler be less and distorted, and the influence of the sliding is different for two different types of the sliding scattering centers: sliding on the surface and sliding on the bottom circle. The analytical expressions of the micro-Doppler are helpful to analyze the time-frequency presentations (TFR of the coning motion of the extended streamlined target and to estimate the parameters of the target.
A. M. Treguier
2007-12-01
Full Text Available An eddying global model is used to study the characteristics of the Antarctic Circumpolar Current (ACC in a streamline-following framework. Previous model-based estimates of the meridional circulation were calculated using zonal averages: this method leads to a counter-intuitive poleward circulation of the less dense waters, and underestimates the eddy effects. We show that on the contrary, the upper ocean circulation across streamlines agrees with the theoretical view: an equatorward mean flow partially cancelled by a poleward eddy mass flux. Two model simulations, in which the buoyancy forcing above the ACC changes from positive to negative, suggest that the relationship between the residual meridional circulation and the surface buoyancy flux is not as straightforward as assumed by the simplest theoretical models: the sign of the residual circulation cannot be inferred from the surface buoyancy forcing only. Among the other processes that likely play a part in setting the meridional circulation, our model results emphasize the complex three-dimensional structure of the ACC (probably not well accounted for in streamline-averaged, two-dimensional models and the distinct role of temperature and salinity in the definition of the density field. Heat and salt transports by the time-mean flow are important even across time-mean streamlines. Heat and salt are balanced in the ACC, the model drift being small, but the nonlinearity of the equation of state cannot be ignored in the density balance.
Remy, Charlie
2012-01-01
This paper provides an overview of EBSCO's new Usage Consolidation product designed to streamline the harvesting, storage, and analysis of usage statistics from electronic resources. Strengths and weaknesses of the product are discussed as well as an early beta partner's experience. In the current atmosphere of flat or declining budgets, libraries…
Fast Automatic Segmentation of White Matter Streamlines Based on a Multi-Subject Bundle Atlas.
Labra, Nicole; Guevara, Pamela; Duclap, Delphine; Houenou, Josselin; Poupon, Cyril; Mangin, Jean-François; Figueroa, Miguel
2017-01-01
This paper presents an algorithm for fast segmentation of white matter bundles from massive dMRI tractography datasets using a multisubject atlas. We use a distance metric to compare streamlines in a subject dataset to labeled centroids in the atlas, and label them using a per-bundle configurable threshold. In order to reduce segmentation time, the algorithm first preprocesses the data using a simplified distance metric to rapidly discard candidate streamlines in multiple stages, while guaranteeing that no false negatives are produced. The smaller set of remaining streamlines is then segmented using the original metric, thus eliminating any false positives from the preprocessing stage. As a result, a single-thread implementation of the algorithm can segment a dataset of almost 9 million streamlines in less than 6 minutes. Moreover, parallel versions of our algorithm for multicore processors and graphics processing units further reduce the segmentation time to less than 22 seconds and to 5 seconds, respectively. This performance enables the use of the algorithm in truly interactive applications for visualization, analysis, and segmentation of large white matter tractography datasets.
Benbassat, Jochanan; Baumal, Reuben
2012-01-01
Undergraduate medical education is too long; it does not meet the needs for physicians' workforce; and its content is inconsistent with the job characteristics of some of its graduates. In this paper we attempt to respond to these problems by streamlining medical education along the following three reforms. First, high school graduates would be…
Brøns, Morten; Hartnack, Johan Nicolai
1999-01-01
Streamline patterns and their bifurcations in two-dimensional incompressible flow are investigated from a topological point of view. The velocity field is expanded at a point in the fluid, and the expansion coefficients are considered as bifurcation parameters. A series of nonlinear coordinate...
Brøns, Morten; Hartnack, Johan Nicolai
1998-01-01
Streamline patterns and their bifurcations in two-dimensional incompressible flow are investigated from a topological point of view. The velocity field is expanded at a point in the fluid, and the expansion coefficients are considered as bifurcation parameters. A series of non-linear coordinate...
Remy, Charlie
2012-01-01
This paper provides an overview of EBSCO's new Usage Consolidation product designed to streamline the harvesting, storage, and analysis of usage statistics from electronic resources. Strengths and weaknesses of the product are discussed as well as an early beta partner's experience. In the current atmosphere of flat or declining budgets, libraries…
The design of the Comet streamliner: An electric land speed record motorcycle
McMillan, Ethan Alexander
The development of the land speed record electric motorcycle streamliner, the Comet, is discussed herein. Its design process includes a detailed literary review of past and current motorcycle streamliners in an effort to highlight the main components of such a vehicle's design, while providing baseline data for performance comparisons. A new approach to balancing a streamliner at low speeds is also addressed, a system henceforth referred to as landing gear, which has proven an effective means for allowing the driver to control the low speed instabilities of the vehicle with relative ease compared to tradition designs. This is accompanied by a dynamic stability analysis conducted on a test chassis that was developed for the primary purpose of understanding the handling dynamics of streamliners, while also providing a test bed for the implementation of the landing gear system and a means to familiarize the driver to the operation and handling of such a vehicle. Data gathered through the use of GPS based velocity tracking, accelerometers, and a linear potentiometer provided a means to validate a dynamic stability analysis of the weave and wobble modes of the vehicle through linearization of a streamliner model developed in the BikeSIM software suite. Results indicate agreement between the experimental data and the simulation, indicating that the conventional recumbent design of a streamliner chassis is in fact highly stable throughout the performance envelope beyond extremely low speeds. A computational fluid dynamics study was also performed, utilized in the development of the body of the Comet to which a series of tests were conducted in order to develop a shape that was both practical to transport and highly efficient. By creating a hybrid airfoil from a NACA 0018 and NACA 66-018, a drag coefficient of 0.1 and frontal area of 0.44 m2 has been found for the final design. Utilizing a performance model based on the proposed vehicle's motor, its rolling resistance, and
Emami, Fereshteh; Masiol, Mauro; Hopke, Philip K
2017-09-11
There have been many changes in the air pollutant sources in the northeastern United States since 2001. To assess the effect of these changes, trend analyses of the monthly average values were performed on PM2.5 and its components including major ions, elemental carbon (EC), organic carbon (OC), and gaseous pollutant concentrations measured between 2001 (in some cases 1999) and 2015 at the NYS Department of Environmental Conservation sites in Rochester, NY. Mann-Kendall regression with Sen's slope was applied to estimate the trends and seasonality. Using piecewise regression, significant reductions in the air pollution of Rochester area were observed between 2008 and 2010 when a 260MW coal-fired power plant was decommissioned, new heavy-duty diesel trucks had to be equipped with catalytic regenerator traps, and the economic recession that began in 2008 reduced traffic and other activities. The monthly average PM2.5 mass showed a downward trend (-5μg/m(3); -41%) in Rochester between 2001 and 2015. This change is largely due to reductions in particulate sulfate that showed a 65% decrease. The sulfate concentrations were compared to changes in SO2 emissions in seventeen upwind source domains, and other systematic changes by multivariate linear regression. Selectivity ratio obtained from target projection discriminated the most important source domains that are SO2 emissions from Georgia for winter, North Carolina for transition (spring and fall) and Ohio along with other influences for summer. North Carolina and Michigan were identified as the main sources for entire period. These observations suggest that any further reductions in the specified regional SO2 emissions would result in a proportional decrease in sulfate in Rochester. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.
Duvall, R. M.; Norris, G. A.; Willis, R. D.; Turner, J. R.; Kaleel, R.; Sweitzer, T.; Preston, B.; Hays, M. D.
2009-04-01
St. Louis is currently in nonattainment of the annual PM2.5 National Ambient Air Quality Standard (NAAQS). Granite City Steel Works (GSCW), located in Granite City, IL is considered to be a significant source impacting the St. Louis area and the largest PM2.5 point source contributor. Twelve grab samples were collected in and around the steel facility including the basic oxygen furnace, steel and iron slag crushing, coal pulverizing, baghouse dust, paved road dust, and unpaved road dust. The bulk samples were resuspended in a resuspension chamber using a PM2.5 cutpoint and collected on Teflon, quartz and polycarbonate filters. Fine particulate matter (PM) samples (12-hr and 24-hr) were collected upwind and downwind of GSCW from October 13 to December 13, 2007 to identify sources contributing to nonattainment in St. Louis. The samples were analyzed for trace metals (X-Ray Fluorescence), ions (Ion Chromatography), elemental and organic carbon (thermal optical analysis), and organic species (solvent extraction Gas Chromatography/Mass Spectrometry). Source apportionment was conducted using the EPA Chemical Mass Balance (CMB) Model (v 8.2). Major sources impacting the 12-hr samples included the blast oxygen furnace, secondary sulfate, and road dust. Higher excess steel and coke works contributions were associated with higher wind speeds (greater than 5 mph) and more variability in source impacts was observed. Major sources impacting the 24-hr samples included secondary sulfate and motor vehicles (diesel and gasoline). Contributions were similar between the coke and steel works sources. Disclaimer: Although this work was reviewed by EPA and approved for publication, it may not necessarily reflect official Agency policy.
Junkermann, W.; Steinbrecher, R.
2009-04-01
During the MILAGRO Campaign March/April 2006 a series of aircraft flights with the FZK microlight D-MIFU were performed in the area southeast of Mexico City starting from Puebla airport, circling the national park area of Ixtachiuatl and Popocatepetl and scanning the Chalco valley down to Cuautla in the Cuernavaca province. All flights were combined with vertical profiles up to 4500 m a.s.l. in several locations, typically north of volcano Ixtachiuatl on the Puebla side, above Chalco or Tenago del Aire and south of volcano Popocatepetl, either at Cuautla or Atlixco. In Tenango del Aire a ceilometer was additionally operated continuously for characterization of the planetary boundary layer. The aircraft carried a set of aerosol instrumentation, fine and coarse particles and size distributions as well as a 7 wavelength aethalometer. Additionally meteorological parameters, temperature and dewpoint, global radiation and actinic radiation balance, respectively photolysis rates, and ozone concentrations were measured. The instrumentation allowed to characterize the aerosol according to their sources and also their impact on radiation transfer. Biomass burning aerosol, windblown dust and volcanic ash were identified within the upwind area of Mexico City with large differences between the dry season in the first weeks of the campaign and the by far cleaner situation after beginning thunderstorm activity towards the end of the campaign. Also the aerosol characteristics inside and outside the Mexico City basin were often completely different. With wind speeds of ~ 5 m/sec from southerly directions in the Chalco valley the aerosol mixture can reach the City within ~ 2 h. Rural aerosol mixtures from the Cuernavaca plain were mixed during the transport with dust from the MC basin. Very high intensity biomass burning plumes normally reached higher altitudes and produced pyrocumulus clouds. These aerosols were injected mainly into the free troposphere. Within the MC basin a large
Sørensen, Niels; Johansen, Jeppe
2007-01-01
Traditionally, rotor computations using CFD (Computational Fluid Dynamics) are performed assuming a uniform inflow with zero shear over the rotor disc. In the present work, time true simulations of a rotor in an atmospheric boundary layer are performed to investigate the unsteady effects due...... to variation of the mean velocity over the rotor disc. The main purpose of these computations are to provide new input to the BEM (Blade Element Momentum) type models used in most engineering codes, concerning the dynamic induction and an eventual phase shifting of the force response with respect...
无
2000-01-01
New form of the constitutive equations for the Oldroyd-B model, which have physical meaning, is developed to facilitate theoretical analysis. The new equations are used to simulate planar 4∶1 contraction flow of a Maxwell fluid using a third-order upwind finite volume method. The numerical results compare well with the theoretical solutions and the results of other references to show the effectiveness of the numerical method. Numerical experiments suggest that the present method not only converges fairly rapidly, but can also generate a highly resolved approximation to an Oldroyd-B fluid flow at a high Weissenberg number.
Xin Wen
2009-01-01
In this paper we give proof of three binomial coefficient inequalities. These inequalities are key ingredients in [Wen and Jin, J. Comput. Math. 26, (2008), 1-22] to establish the L1-error estimates for the upwind difference scheme to the linear advection equations with a piecewise constant wave speed and a general interface condition, which were further used to establish the L1-error estimates for a Hamiltonian-preserving scheme developed in [Jin and Wen, Commun. Math. Sci. 3, (2005), 285-315] to the Liouville equation with piecewise constant potentials [Wen and Jin, SIAM J. Numer. Anal. 46, (2008), 2688-2714].
U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office; Bechtel Nevada
2004-05-01
This Streamlined Approach for Environmental Restoration (SAFER) plan details the activities necessary to close Corrective Action Unit 496: Buried Rocket Site, Antelope Lake. CAU 496 consists of one site located at the Tonopah Test Range, Nevada.
H.D. Pruijt (Hans)
2010-01-01
textabstractInterviewStreamliner is a free, open source, minimalist alternative to complex computer-assisted qualitative data analysis packages. It builds on the flexibility of relational database management technology.
Papaloizou, J C B
2004-01-01
We carry out a general study of the stability of astrophysical flows that appear steady in a uniformly rotating frame. Such a flow might correspond to a stellar pulsation mode or an accretion disk with a free global distortion giving it finite eccentricity. We consider perturbations arbitrarily localized in the neighbourhood of unperturbed fluid streamlines.When conditions do not vary around them, perturbations take the form of oscillatory inertial or gravity modes. However, when conditions do vary so that a circulating fluid element is subject to periodic variations, parametric instability may occur. For nearly circular streamlines, the dense spectra associated with inertial or gravity modes ensure that resonance conditions can always be satisfied when twice the period of circulation round a streamline falls within. We apply our formalism to a differentially rotating disk for which the streamlines are Keplerian ellipses, with free eccentricity up to 0.7, which do not precess in an inertial frame. We show tha...
Schmidt Paulsen, U.
2011-02-15
The present report is the final effort of tasks carried out under UPWIND WP1B2 transmission and conversion, which describes: 1) results and recommendations developed in the course of developing the long-term load measurement technique. 2) the hardware details, type of sensors and location, data storage and. 3) data analysis technique to verify design load assumptions. The work is carried out under Contract no 019945 (SES6) 'UPWIND' within the European Commission The interaction between the mechanical and electrical generator subsystems is described rudimentarily, based primarily on HAWC2 simulations below stall of the mechanical system with simple generator and gearbox systems. The electrical system simulations were not carried out as intended in DOW[2], but indications of the conditions for establishing the interaction have been described by measurements and by argument, that this might have an effect as indicated. The hypothesis stating, that the power signal can be utilized as a basic signal for extended analysis of mechanical as well as electrical power signal with static and dynamic features, has been demonstrated on performance and dynamic bandwidth capability. It is however from present analysis obvious that improved signal conditions could be achieved with other mechanical joint solutions than with the present torque signal as measured with the cardan joint. For the reasons mentioned, the comparison with a signal showing the mechanical properties could be improved, with a likely gain on the accuracy as a result. (Author)
Methodology for the Design of Streamline-Traced External-Compression Supersonic Inlets
Slater, John W.
2014-01-01
A design methodology based on streamline-tracing is discussed for the design of external-compression, supersonic inlets for flight below Mach 2.0. The methodology establishes a supersonic compression surface and capture cross-section by tracing streamlines through an axisymmetric Busemann flowfield. The compression system of shock and Mach waves is altered through modifications to the leading edge and shoulder of the compression surface. An external terminal shock is established to create subsonic flow which is diffused in the subsonic diffuser. The design methodology was implemented into the SUPIN inlet design tool. SUPIN uses specified design factors to design the inlets and computes the inlet performance, which includes the flow rates, total pressure recovery, and wave drag. A design study was conducted using SUPIN and the Wind-US computational fluid dynamics code to design and analyze the properties of two streamline-traced, external-compression (STEX) supersonic inlets for Mach 1.6 freestream conditions. The STEX inlets were compared to axisymmetric pitot, two-dimensional, and axisymmetric spike inlets. The STEX inlets had slightly lower total pressure recovery and higher levels of total pressure distortion than the axisymmetric spike inlet. The cowl wave drag coefficients of the STEX inlets were 20% of those for the axisymmetric spike inlet. The STEX inlets had external sound pressures that were 37% of those of the axisymmetric spike inlet, which may result in lower adverse sonic boom characteristics. The flexibility of the shape of the capture cross-section may result in benefits for the integration of STEX inlets with aircraft.
Stable–streamlined and helical cavities following the impact of Leidenfrost spheres
Mansoor, Mohammad M.
2017-06-23
We report results from an experimental study on the formation of stable–streamlined and helical cavity wakes following the free-surface impact of Leidenfrost spheres. Similar to the observations of Mansoor et al. (J. Fluid Mech., vol. 743, 2014, pp. 295–326), we show that acoustic ripples form along the interface of elongated cavities entrained in the presence of wall effects as soon as the primary cavity pinch-off takes place. The crests of these ripples can act as favourable points for closure, producing multiple acoustic pinch-offs, which are found to occur in an acoustic pinch-off cascade. We show that these ripples pacify with time in the absence of physical contact between the sphere and the liquid, leading to extremely smooth cavity wake profiles. More importantly, the downward-facing jet at the apex of the cavity is continually suppressed due to a skin-friction drag effect at the colliding cavity-wall junction, which ultimately produces a stable–streamlined cavity wake. This streamlined configuration is found to experience drag coefficients an order of a magnitude lower than those acting on room-temperature spheres. A striking observation is the formation of helical cavities which occur for impact Reynolds numbers and are characterized by multiple interfacial ridges, stemming from and rotating synchronously about an evident contact line around the sphere equator. The contact line is shown to result from the degeneration of Kelvin–Helmholtz billows into turbulence which are observed forming along the liquid–vapour interface around the bottom hemisphere of the sphere. Using sphere trajectory measurements, we show that this helical cavity wake configuration has 40 %–55 % smaller force coefficients than those obtained in the formation of stable cavity wakes.
A majority rule approach for region-of-interest-guided streamline fiber tractography.
Colon-Perez, L M; Triplett, W; Bohsali, A; Corti, M; Nguyen, P T; Patten, C; Mareci, T H; Price, C C
2016-12-01
Hand-drawn gray matter regions of interest (ROI) are often used to guide the estimation of white matter tractography, obtained from diffusion-weighted magnetic resonance imaging (DWI), in healthy and in patient populations. However, such ROIs are vulnerable to rater bias of the individual segmenting the ROIs, scan variability, and individual differences in neuroanatomy. In this report, a "majority rule" approach is introduced for ROI segmentation used to guide streamline tractography in white matter structures. DWI of one healthy participant was acquired in ten separate sessions using a 3 T scanner over the course of a month. Four raters identified ROIs within the left hemisphere [Cerebral Peduncle (CPED); Internal Capsule (IC); Hand Portion of the Motor Cortex, or Hand Bump, (HB)] using a group-established standard operating procedure for ROI definition to guide the estimation of streamline tracts within the corticospinal tract (CST). Each rater traced the ROIs twice for each scan session. The overlap of each rater's two ROIs was used to define a representative ROI for each rater. These ROIs were combined to create a "majority rules" ROI, in which the rule requires that each voxel is selected by at least three of four raters. Reproducibility for ROIs and CST segmentations were analyzed with the Dice Similarity Coefficient (DSC). Intra-rater reliability for each ROI was high (DSCs ≥ 0.83). Inter-rater reliability was moderate to adequate (DSC range 0.54-0.75; lowest for IC). Using intersected majority rules ROIs, the resulting CST showed improved overlap (DSC = 0.82) in the estimated streamline tracks for the ten sessions. Despite high intra-rater reliability, there was lower inter-rater reliability consistent with the expectation of rater bias. Employing the majority rules method improved reliability in the overlap of the CST.
Streamlined mean field variational Bayes for longitudinal and multilevel data analysis.
Lee, Cathy Yuen Yi; Wand, Matt P
2016-07-01
Streamlined mean field variational Bayes algorithms for efficient fitting and inference in large models for longitudinal and multilevel data analysis are obtained. The number of operations is linear in the number of groups at each level, which represents a two orders of magnitude improvement over the naïve approach. Storage requirements are also lessened considerably. We treat models for the Gaussian and binary response situations. Our algorithms allow the fastest ever approximate Bayesian analyses of arbitrarily large longitudinal and multilevel datasets, with little degradation in accuracy compared with Markov chain Monte Carlo. The modularity of mean field variational Bayes allows relatively simple extension to more complicated scenarios.
Hawkins, S.C. [Eckenfelder Inc., Greenville, SC (United States)
1997-12-31
In today`s competitive work environment it is becoming increasingly important for industry to comply with environmental regulations and standards while minimizing cost on pollution control systems. This often requires innovative new solutions to existing environmental challenges. Strategic environmental planning and process optimization are key elements in cost-effective environmental management. The permanent total enclosure can be a useful tool in the strategic environmental planning process. This paper discusses the installation of a permanent total enclosure at a southeastern printing and publishing industry. By constructing the total enclosure the industry was able to streamline the permitting process and reduce pollutant emissions while simultaneously reducing cost and saving money.
Health Equity and Financial Protection Streamlined Analysis with ADePT Software
Bank, World
2011-01-01
Two key policy goals in the health sector are equity and financial protection. New methods, data and powerful computers have led to a surge of interest in quantitative analysis that permits monitoring progress toward these objectives, and comparisons across countries. ADePT is a new computer program that streamlines and automates such work, ensuring that results are genuinely comparable and allowing them to be produced with a minimum of programming skills. This book provides a step-by-step guide to the use of ADePT for quantitative analysis of equity and financial protection in the health sect
Burr, D. M.; Emery, J. P.; Lorenz, R. D.
2005-01-01
The Cassini Imaging Science System (ISS) has been returning images of Titan, along with other Saturnian satellites. Images taken through the 938 nm methane window see down to Titan's surface. One of the purposes of the Cassini mission is to investigate possible fluid cycling on Titan. Lemniscate features shown recently and radar evidence of surface flow prompted us to consider theoretically the creation by methane fluid flow of streamlined forms on Titan. This follows work by other groups in theoretical consideration of fluid motion on Titan's surface.
Non-invasive Estimation of Pressure Changes along a Streamline using Vector Velocity Ultrasound
Olesen, Jacob Bjerring; Villagómez Hoyos, Carlos Armando; Traberg, Marie Sand;
2015-01-01
estimator is evaluated by comparing its results to a 3-D numerical simulation model. The study showed pressure drops across the constricted phantom varying from -5 Pa to 7 Pa with a standard deviation of 4%. The proposed method had a normalised rootmean-square error of 10% in reference to the simulation......A non-invasive method for estimating pressure changes along a streamline using ultrasound is presented. The suggested method estimates pressure gradients from 2-D vector velocity fields. Changes in pressure are derived using a model based on the Navier-Stokes equations. Scans of a carotid...
Adaptive finite element simulation of flow and transport applications on parallel computers
Kirk, Benjamin Shelton
design and to demonstrate the capability for resolving complex multiscale processes efficiently and reliably. The first application considered is the simulation of chemotactic biological systems such as colonies of Escherichia coli. This work appears to be the first application of AMR to chemotactic processes. These systems exhibit transient, highly localized features and are important in many biological processes, which make them ideal for simulation with adaptive techniques. A nonlinear reaction-diffusion model for such systems is described and a finite element formulation is developed. The solution methodology is described in detail. Several phenomenological studies are conducted to study chemotactic processes and resulting biological patterns which use the parallel adaptive refinement capability developed in this work. The other application study is much more extensive and deals with fine scale interactions for important hypersonic flows arising in aerospace applications. These flows are characterized by highly nonlinear, convection-dominated flowfields with very localized features such as shock waves and boundary layers. These localized features are well-suited to simulation with adaptive techniques. A novel treatment of the inviscid flux terms arising in a streamline-upwind Petrov-Galerkin finite element formulation of the compressible Navier-Stokes equations is also presented and is found to be superior to the traditional approach. The parallel adaptive finite element formulation is then applied to several complex flow studies, culminating in fully three-dimensional viscous flows about complex geometries such as the Space Shuttle Orbiter. Physical phenomena such as viscous/inviscid interaction, shock wave/boundary layer interaction, shock/shock interaction, and unsteady acoustic-driven flowfield response are considered in detail. A computational investigation of a 25°/55° double cone configuration details the complex multiscale flow features and investigates a
Modelling free surface flow with curvilinear streamlines by a non-hydrostatic model
Zerihun Yebegaeshet T.
2016-09-01
Full Text Available This study addresses a particular phenomenon in open channel flows for which the basic assumption of hydrostatic pressure distribution is essentially invalid, and expands previous suggestions to flows where streamline curvature is significant. The proposed model incorporates the effects of the vertical curvature of the streamline and steep slope, in making the pressure distribution non-hydrostatic, and overcomes the accuracy problem of the Saint-Venant equations when simulating curvilinear free surface flow problems. Furthermore, the model is demonstrated to be a higher-order one-dimensional model that includes terms accounting for wave-like variations of the free surface on a constant slope channel. Test results of predicted flow surface and pressure profiles for flow in a channel transition from mild to steep slopes, transcritical flow over a short-crested weir and flow with dual free surfaces are compared with experimental data and previous numerical results. A good agreement is attained between the experimental and computed results. The overall simulation results reveal the satisfactory performance of the proposed model in simulating rapidly varied gravity-driven flows with predominant non-hydrostatic pressure distribution effects. This study suggests that a higher-order pressure equation should be used for modelling the pressure distribution of a curvilinear flow in a steeply sloping channel.
Streamlining the process: A strategy for making NEPA work better and cost less
Hansen, R.P.; Hansen, J.D. [Hansen Environmental Consultants, Englewood, CO (United States); Wolff, T.A. [Sandia National Labs., Albuquerque, NM (United States)
1998-05-01
When the National Environmental Policy Act (NEPA) was enacted in 1969, neither Congress nor the Federal Agencies affected anticipated that implementation of the NEPA process would result in the intolerable delays, inefficiencies, duplication of effort, commitments of excessive financial and personnel resources, and bureaucratic gridlock that have become institutionalized. The 1975 Council on Environmental Quality (CEQ) regulations, which were intended to make the NEPA process more efficient and more useful to decision makers and the public, have either been largely ignored or unintentionally subverted. Agency policy mandates, like those of former Secretary of Energy Hazel R. O`Leary, to ``make NEPA work better and cost less`` have, so far, been disappointingly ineffectual. Federal Agencies have reached the point where almost every constituent of the NEPA process must be subjected to crisis management. This paper focuses on a ten-point strategy for streamlining the NEPA process in order to achieve the Act`s objectives while easing the considerable burden on agencies, the public, and the judicial system. How the ten points are timed and implemented is critical to any successful streamlining.
Streamlining and core genome conservation among highly divergent members of the SAR11 clade.
Grote, Jana; Thrash, J Cameron; Huggett, Megan J; Landry, Zachary C; Carini, Paul; Giovannoni, Stephen J; Rappé, Michael S
2012-01-01
SAR11 is an ancient and diverse clade of heterotrophic bacteria that are abundant throughout the world's oceans, where they play a major role in the ocean carbon cycle. Correlations between the phylogenetic branching order and spatiotemporal patterns in cell distributions from planktonic ocean environments indicate that SAR11 has evolved into perhaps a dozen or more specialized ecotypes that span evolutionary distances equivalent to a bacterial order. We isolated and sequenced genomes from diverse SAR11 cultures that represent three major lineages and encompass the full breadth of the clade. The new data expand observations about genome evolution and gene content that previously had been restricted to the SAR11 Ia subclade, providing a much broader perspective on the clade's origins, evolution, and ecology. We found small genomes throughout the clade and a very high proportion of core genome genes (48 to 56%), indicating that small genome size is probably an ancestral characteristic. In their level of core genome conservation, the members of SAR11 are outliers, the most conserved free-living bacteria known. Shared features of the clade include low GC content, high gene synteny, a large hypervariable region bounded by rRNA genes, and low numbers of paralogs. Variation among the genomes included genes for phosphorus metabolism, glycolysis, and C1 metabolism, suggesting that adaptive specialization in nutrient resource utilization is important to niche partitioning and ecotype divergence within the clade. These data provide support for the conclusion that streamlining selection for efficient cell replication in the planktonic habitat has occurred throughout the evolution and diversification of this clade. IMPORTANCE The SAR11 clade is the most abundant group of marine microorganisms worldwide, making them key players in the global carbon cycle. Growing knowledge about their biochemistry and metabolism is leading to a more mechanistic understanding of organic carbon
SIMULATION OF STRONG TURBULENCE FLOW WITH FREE SURFACE INCLUDING THE EFFECTS OF STREAMLINE CURVATURE
DAI Hui-chao; LIU Yu-ling; WEI Wen-li
2005-01-01
This paper is concerned with a mathematical model for two-dimensional strong turbulence flow with free surface including the effects of streamline curvature in orthogonal curvilinear coordinate system, with which the characteristics of the turbulence flow field on the ogee spillway was numerical simulated. In the numerical simulation, the flow control equations in orthogonal curvilinear coordinate system were discretized by the finite volume method, the physical parameters( P, U,V,K,ε,γt,etc.) were arranged on a staggered grid, the discretized equations were solved with the SIMPLEC method, and the complex free surface was dealt with VOF method. The computed results show that the velocity fields, pressure field, shear stress distribution and kinetic energy of turbulent flow on the ogee spillway are in agreement with experimental data. This confirms that the model can be used for numerical simulation of the turbulence flow on ogee spillway.
Streamlining the analytical workflow for multiplex MS/MS allergen detection in processed foods.
Pilolli, Rosa; De Angelis, Elisabetta; Monaci, Linda
2017-04-15
Allergenic ingredients in pre-packaged foods are regulated by EU legislation mandating their inclusion on labels. In order to protect allergic consumers, sensitive analytical methods are required for detect allergen traces in different food products. As a follow-up to our previous investigations, an optimized, sensitive, label-free LC-MS/MS method for multiplex detection of five allergenic ingredients in a processed food matrix is proposed. A cookie base was chosen as a complex food matrix and home-made cookies incurred with whole egg, skimmed milk, soy flour, ground hazelnut and ground peanut were prepared at laboratory scale. In order to improve the analytical workflow both protein extraction and purification protocols were optimized and finally a sensitive streamlined SRM based analytical method for allergens detection in incurred cookies was devised. The effect of baking on the detection of selected markers was also investigated. Copyright © 2016 Elsevier Ltd. All rights reserved.
Off-Design Performance of a Streamline-Traced, External-Compression Supersonic Inlet
Slater, John W.
2017-01-01
A computational study was performed to explore the aerodynamic performance of a streamline-traced, external-compression inlet designed for Mach 1.664 at off-design conditions of freestream Mach number, angle-of-attack, and angle-of-sideslip. Serious degradation of the inlet performance occurred for negative angles-of-attack and angles-of-sideslip greater than 3 degrees. At low subsonic speeds, the swept leading edges of the inlet created a pair of vortices that propagated to the engine face. Increasing the bluntness of the cowl lip showed no real improvement in the inlet performance at the low speeds, but did improve the inlet performance at the design conditions. Reducing the inlet flow rate improved the inlet performance, but at the likely expense of reduced thrust of the propulsion system. Deforming the cowl lip for low-speed operation of the inlet increased the inlet capture area and improved the inlet performance.
Begemann, Matthew B; Mormile, Melanie R; Sitton, Oliver C; Wall, Judy D; Elias, Dwayne A
2012-01-01
Biofuels are anticipated to enable a shift from fossil fuels for renewable transportation and manufacturing fuels, with biohydrogen considered attractive since it could offer the largest reduction of global carbon budgets. Currently, lignocellulosic biohydrogen production remains inefficient with pretreatments that are heavily fossil fuel-dependent. However, bacteria using alkali-treated biomass could streamline biofuel production while reducing costs and fossil fuel needs. An alkaliphilic bacterium, Halanaerobiumhydrogeniformans, is described that is capable of biohydrogen production at levels rivaling neutrophilic strains, but at pH 11 and hypersaline conditions. H. hydrogeniformans ferments a variety of 5- and 6-carbon sugars derived from hemicellulose and cellulose including cellobiose, and forms the end products hydrogen, acetate, and formate. Further, it can also produce biohydrogen from switchgrass and straw pretreated at temperatures far lower than any previously reported and in solutions compatible with growth. Hence, this bacterium can potentially increase the efficiency and efficacy of biohydrogen production from renewable biomass resources.
Matthew eBegemann
2012-03-01
Full Text Available Biofuels are anticipated to enable a shift from fossil fuels for renewable transportation and manufacturing fuels, with biohydrogen considered attractive since it could offer the largest reduction of global carbon budgets. Currently, lignocellulosic biohydrogen production remains inefficient with pretreatments that are heavily fossil fuel-dependent. However, bacteria using alkali-treated biomass could streamline biofuel production while reducing costs and fossil fuel needs. An alkaliphilic bacterium, Halanaerobium hydrogeniformans, is described that is capable of biohydrogen production at levels rivaling neutrophilic strains, but at pH 11 and hypersaline conditions. H. hydrogeniformans ferments a variety of 5- and 6- carbon sugars derived from hemicellulose and cellulose including cellobiose, and forms the end products hydrogen, acetate and formate. Further, it can also produce biohydrogen from switchgrass and straw pretreated at temperatures far lower than any previously reported and in solutions compatible with growth. Hence, this bacterium can potentially increase the efficiency and efficacy of biohydrogen production from renewable biomass resources.
Signatures of quantum chaos in nodal points and streamlines in electron transport through billiards
Berggren, K F; Sadreev, A F; Starikov, A A; Berggren, Karl-Fredrik; Pichugin, Konstantin N.; Sadreev, Almas F.; Starikov, Anton
1999-01-01
Streamlines and distributions of nodal points are used as signatures of chaos in coherent electron transport through three types of billiards, Sinai, Bunimovich and rectangular. Numerical averaged distribution functions of nearest distances between nodal points are presented. We find the same form for the Sinai and Bunimovich billiards and suggest that there is a universal form that can be used as a signature of quantum chaos for electron transport in open billiards. The universal distribution function is found to be insensitive to the way avaraging is performed (over positions of leads, over an energy interval with a few conductance fluctuations, or both). The integrable rectangular billiard, on the other hand, displays nonuniversal distribution with a central peak related to partial order of nodal points for the case of symmetric attachment of leads. However cases with nonsymmetric leads tend to the universal form. Also it is shown how nodal points in rectangular billiard can lead to "channeling of quantum ...
Schulz, Matthias; Short, Michael D; Peters, Gregory M
2012-01-01
Water supply is a key consideration in sustainable urban planning. Ideally, detailed quantitative sustainability assessments are undertaken during the planning stage to inform the decision-making process. In reality, however, the significant time and cost associated with undertaking such detailed environmental and economic assessments is often cited as a barrier to wider implementation of these key decision support tools, particularly for decisions made at the local or regional government level. In an attempt to overcome this barrier of complexity, 4 water service providers in Melbourne, Australia, funded the development of a publicly available streamlined Environmental Sustainability Assessment Tool, which is aimed at a wide range of decision makers to assist them in broadening the type and number of water servicing options that can be considered for greenfield or backlog developments. The Environmental Sustainability Assessment Tool consists of a simple user interface and draws on life cycle inventory data to allow for rapid estimation of the environmental and economic performance of different water servicing scenarios. Scenario options can then be further prioritized by means of an interactive multicriteria analysis. The intent of this article is to identify the key issues to be considered in a streamlined sustainability assessment tool for the urban water industry, and to demonstrate the feasibility of generating accurate life cycle assessments and life cycle costings, using such a tool. We use a real-life case study example consisting of 3 separate scenarios for a planned urban development to show that this kind of tool can emulate life cycle assessments and life cycle costings outcomes obtained through more detailed studies. This simplified approach is aimed at supporting "sustainability thinking" early in the decision-making process, thereby encouraging more sustainable water and sewerage infrastructure solutions.
Locke, Edward
2009-01-01
This article presents a proposed model for a clear description of K-12 age-possible engineering knowledge content, in terms of the selection of analytic principles and predictive skills for various grades, based on the mastery of mathematics and science pre-requisites, as mandated by national or state performance standards; and a streamlined,…
NONE
2006-07-01
This Streamlined Approach for Environmental Restoration Plan identifies the activities required for the closure of Corrective Action Unit 116, Area 25 Test Cell C Facility. The Test Cell C Facility is located in Area 25 of the Nevada Test Site approximately 25 miles northwest of Mercury, Nevada.
Glocer, A.; Toth, G.; Ma, Y.; Gombosi, T.; Zhang, J.-C.; Kistler, L. M.
2009-01-01
The magnetosphere contains a significant amount of ionospheric O+, particularly during geomagnetically active times. The presence of ionospheric plasma in the magnetosphere has a notable impact on magnetospheric composition and processes. We present a new multifluid MHD version of the Block-Adaptive-Tree Solar wind Roe-type Upwind Scheme model of the magnetosphere to track the fate and consequences of ionospheric outflow. The multifluid MHD equations are presented as are the novel techniques for overcoming the formidable challenges associated with solving them. Our new model is then applied to the May 4, 1998 and March 31, 2001 geomagnetic storms. The results are juxtaposed with traditional single-fluid MHD and multispecies MHD simulations from a previous study, thereby allowing us to assess the benefits of using a more complex model with additional physics. We find that our multifluid MHD model (with outflow) gives comparable results to the multispecies MHD model (with outflow), including a more strongly negative Dst, reduced CPCP, and a drastically improved magnetic field at geosynchronous orbit, as compared to single-fluid MHD with no outflow. Significant differences in composition and magnetic field are found between the multispecies and multifluid approach further away from the Earth. We further demonstrate the ability to explore pressure and bulk velocity differences between H+ and O+, which is not possible when utilizing the other techniques considered
Glocer, A.; Toth, G.; Ma, Y.; Gombosi, T.; Zhang, J.-C.; Kistler, L. M.
2009-01-01
The magnetosphere contains a significant amount of ionospheric O+, particularly during geomagnetically active times. The presence of ionospheric plasma in the magnetosphere has a notable impact on magnetospheric composition and processes. We present a new multifluid MHD version of the Block-Adaptive-Tree Solar wind Roe-type Upwind Scheme model of the magnetosphere to track the fate and consequences of ionospheric outflow. The multifluid MHD equations are presented as are the novel techniques for overcoming the formidable challenges associated with solving them. Our new model is then applied to the May 4, 1998 and March 31, 2001 geomagnetic storms. The results are juxtaposed with traditional single-fluid MHD and multispecies MHD simulations from a previous study, thereby allowing us to assess the benefits of using a more complex model with additional physics. We find that our multifluid MHD model (with outflow) gives comparable results to the multispecies MHD model (with outflow), including a more strongly negative Dst, reduced CPCP, and a drastically improved magnetic field at geosynchronous orbit, as compared to single-fluid MHD with no outflow. Significant differences in composition and magnetic field are found between the multispecies and multifluid approach further away from the Earth. We further demonstrate the ability to explore pressure and bulk velocity differences between H+ and O+, which is not possible when utilizing the other techniques considered
Darwin Core Based Data Streamlining with DigiMus 2.0
Aditya P Kakodkar
2009-01-01
Full Text Available Cataloguing biological specimen is a important activity of biological museums world over. Software developed especially for this purpose have evolved overtime to achieve more accuracy in retrieving data from large and diverse datasets. Combining smaller datasets in to a larger information system requires uniformity of data based on a single data standard. In the developing world smaller datasets are maintained by individual researchers or small college and university groups. For standardizing data from such datasets, software needs to be developed, which require expertise and sufficient funds which are often unavailable. We present a simple open source web based tool developed using PHP to enable an individual with little or no knowledge of information systems or databases, to effectively streamline specimen data with data standard Darwin Core 1.2 ( DwC 1.2. Such data can then be shared and easily provided to larger datasets like Ocean Biogeographic Information Systems (OBIS and Global Biodiversity Information Facility (GBIF. This tool can be accessed at http://www.niobioinformatics.in/digimus.php and its source code is freely available at http://www.niobioinformatics.in/digimus_source.php
Horan, Thomas A; Daniels, Susan M; Feldman, Sue S
2009-07-01
The disability community could benefit significantly from the widespread adoption of health information technology, in particular from its ability to streamline and accelerate processing of the estimated 3 million disability benefits applications filed with the Social Security Administration each year. Disability determination is an inefficient, largely paper-based process requiring large volumes of clinical data compiled from multiple provider sources. That, coupled with a lack of transparency within the process, adds unnecessary delays and expense. The objective of this paper is to outline the case for how personal health records, particularly those populated with information from provider-held electronic health records and payer claims data, offer a means to achieve financial savings from shortened disability determination processes, as well as a tool for disability health self-management and care coordination. Drawing from research and policy forums and testimony before the American Health Information Community, the importance of including the disability community as the nation moves forward with health information technology initiatives is explored. Our research suggests that systemwide improvements such as the Nationwide Health Information Network and other such health information technology initiatives could be used to bring benefits to the disability community. The time has come to use health information technology initiatives so that federal policy makers can takes steps to reduce the inefficiencies in the Social Security Administration disability determination process while improving the program's value to those who need it the most.
Surrogate Based Optimization of Aerodynamic Noise for Streamlined Shape of High Speed Trains
Zhenxu Sun
2017-02-01
Full Text Available Aerodynamic noise increases with the sixth power of the running speed. As the speed increases, aerodynamic noise becomes predominant and begins to be the main noise source at a certain high speed. As a result, aerodynamic noise has to be focused on when designing new high-speed trains. In order to perform the aerodynamic noise optimization, the equivalent continuous sound pressure level (SPL has been used in the present paper, which could take all of the far field observation probes into consideration. The Non-Linear Acoustics Solver (NLAS approach has been utilized for acoustic calculation. With the use of Kriging surrogate model, a multi-objective optimization of the streamlined shape of high-speed trains has been performed, which takes the noise level in the far field and the drag of the whole train as the objectives. To efficiently construct the Kriging model, the cross validation approach has been adopted. Optimization results reveal that both the equivalent continuous sound pressure level and the drag of the whole train are reduced in a certain extent.
Pinhal, Danillo; Shivji, Mahmood S; Nachtigall, Pedro G; Chapman, Demian D; Martins, Cesar
2012-01-01
Obtaining accurate species-specific landings data is an essential step toward achieving sustainable shark fisheries. Globally distributed sharpnose sharks (genus Rhizoprionodon) exhibit life-history characteristics (rapid growth, early maturity, annual reproduction) that suggests that they could be fished in a sustainable manner assuming an investment in monitoring, assessment and careful management. However, obtaining species-specific landings data for sharpnose sharks is problematic because they are morphologically very similar to one another. Moreover, sharpnose sharks may also be confused with other small sharks (either small species or juveniles of large species) once they are processed (i.e., the head and fins are removed). Here we present a highly streamlined molecular genetics approach based on seven species-specific PCR primers in a multiplex format that can simultaneously discriminate body parts from the seven described sharpnose shark species commonly occurring in coastal fisheries worldwide. The species-specific primers are based on nucleotide sequence differences among species in the nuclear ribosomal internal transcribed spacer 2 locus (ITS2). This approach also distinguishes sharpnose sharks from a wide range of other sharks (52 species) and can therefore assist in the regulation of coastal shark fisheries around the world.
Streamlining Metadata Ingest and Discovery Using ECHO's REST-based API
Ericson, R.; Baynes, K.; Pilone, D.
2012-12-01
Enabling user access to Earth science data is a primary goal of NASA's Earth Observing System Data and Information Systems (EOSDIS) programs. NASA's Earth Observing System ClearingHOuse (ECHO) acts as the core metadata repository for EOSDIS's data centers, providing a centralized mechanism for metadata and data discovery and retrieval. ECHO has recently made strides to restructure its API; allowing data partners to streamline and synchronize their metadata ingest using RESTful web services. ECHO's legacy ingest process involves data uploads via FTP with asynchronous result reporting. Data centers provide single xml files or compressed data (zip) files that are unpacked, indexed and stored in ECHO data tables for future search and retrieval. Any problems related to metadata validation and ingest are reported after batch processing of discrete jobs have been completed. With ECHO's new REST-based web services, data providers will receive immediate feedback about the status of their ingested data and can ensure that their data exports are successful as soon as the data is posted to our repository. This presentation will introduce ECHO's potential new and existing data partners to the process of implementing data ingest via its RESTful web services API, providing real-world examples of end-to-end metadata management. Examples of ECHO's support of multi-format metadata ingest using both ECHO10 and ISO 19115 metadata formats will be showcased. This presentation will also pay special attention to tuning a provider's metadata, making it more easily searched and accessed via ECHO's various interfaces.
Azizian, Morvarid; Grant, Stanley B; Kessler, Adam J; Cook, Perran L M; Rippy, Megan A; Stewardson, Michael J
2015-09-15
Bedforms are a focal point of carbon and nitrogen cycling in streams and coastal marine ecosystems. In this paper, we develop and test a mechanistic model, the "pumping and streamline segregation" or PASS model, for nitrate removal in bedforms. The PASS model dramatically reduces computational overhead associated with modeling nitrogen transformations in bedforms and reproduces (within a factor of 2 or better) previously published measurements and models of biogeochemical reaction rates, benthic fluxes, and in-sediment nutrient and oxygen concentrations. Application of the PASS model to a diverse set of marine and freshwater environments indicates that (1) physical controls on nitrate removal in a bedform include the pore water flushing rate, residence time distribution, and relative rates of respiration and transport (as represented by the Damkohler number); (2) the biogeochemical pathway for nitrate removal is an environment-specific combination of direct denitrification of stream nitrate and coupled nitrification-denitrification of stream and/or sediment ammonium; and (3) permeable sediments are almost always a net source of dissolved inorganic nitrogen. The PASS model also provides a mechanistic explanation for previously published empirical correlations showing denitrification velocity (N2 flux divided by nitrate concentration) declines as a power law of nitrate concentration in a stream (Mulholland et al. Nature, 2008, 452, 202-205).
Uhlmann, Wendy R; Schwalm, Katie; Raymond, Victoria M
2017-08-01
Obtaining genetic testing insurance authorizations for patients is a complex, time-involved process often requiring genetic counselor (GC) and physician involvement. In an effort to mitigate this complexity and meet the increasing number of genetic testing insurance authorization requests, GCs formed a novel partnership with an industrial engineer (IE) and a patient services associate (PSA) to develop a streamlined work flow. Eight genetics clinics and five specialty clinics at the University of Michigan were surveyed to obtain benchmarking data. Tasks needed for genetic testing insurance authorization were outlined and time-saving work flow changes were introduced including 1) creation of an Excel password-protected shared database between GCs and PSAs, used for initiating insurance authorization requests, tracking and follow-up 2) instituting the PSAs sending GCs a pre-clinic email noting each patients' genetic testing insurance coverage 3) inclusion of test medical necessity documentation in the clinic visit summary note instead of writing a separate insurance letter and 4) PSAs development of a manual with insurance providers and genetic testing laboratories information. These work flow changes made it more efficient to request and track genetic testing insurance authorizations for patients, enhanced GCs and PSAs communication, and reduced tasks done by clinicians.
Localized Plasticity in the Streamlined Genomes of Vinyl Chloride Respiring Dehalococcoides
McMurdie, Paul J.; Behrens, Sebastien F.; Muller, Jochen A.; Goke, Jonathan; Ritalahti, Kirsti M.; Wagner, Ryan; Goltsman, Eugene; Lapidus, Alla; Holmes, Susan; Loffler, Frank E.; Spormann, Alfred M.
2009-06-30
Vinyl chloride (VC) is a human carcinogen and widespread priority pollutant. Here we report the first, to our knowledge, complete genome sequences of microorganisms able to respire VC, Dehalococcoides sp. strains VS and BAV1. Notably, the respective VC reductase encoding genes, vcrAB and bvcAB, were found embedded in distinct genomic islands (GEIs) with different predicted integration sites, suggesting that these genes were acquired horizontally and independently by distinct mechanisms. A comparative analysis that included two previously sequenced Dehalococcoides genomes revealed a contextually conserved core that is interrupted by two high plasticity regions (HPRs) near the Ori. These HPRs contain the majority of GEIs and strain-specific genes identified in the four Dehalococcoides genomes, an elevated number of repeated elements including insertion sequences (IS), as well as 91 of 96 rdhAB, genes that putatively encode terminal reductases in organohalide respiration. Only three core rdhA orthologous groups were identified, and only one of these groups is supported by synteny. The low number of core rdhAB, contrasted with the high rdhAB numbers per genome (up to 36 in strain VS), as well as their colocalization with GEIs and other signatures for horizontal transfer, suggests that niche adaptation via organohalide respiration is a fundamental ecological strategy in Dehalococccoides. This adaptation has been exacted through multiple mechanisms of recombination that are mainly confined within HPRs of an otherwise remarkably stable, syntenic, streamlined genome among the smallest of any free-living microorganism.
The Benefits of Streamlined Hip Fracture Management in a Regional Hospital.
Mow, T C; Lukeis, Jen; Sutherland, A G
2017-06-01
Hip fracture is an increasingly common injury in the growing elderly population. The morbidity and mortality associated with this injury can be reduced by minimizing delays to surgical treatment. We describe the impact of a regional hospital service redesign project that utilized the principles of smart simplicity, a management strategy that lays emphasis on collaboration to achieve desired goals. Prior to the redesign, patients with hip fractures were taking an average of 72 hours for surgical treatment. A hip fracture working group was created to examine closely the process of hip fracture care, and a single key performance indicator (KPI) of "surgery within 48 hours" was adopted. This allowed identification of processes that could be clarified and streamlined, with the agreement of relevant stakeholders, in the creation of a new hip fracture pathway. In the first 3 months of the pathway's implementation, 16 of 18 patients had surgery within 48 hours of presentation. In a 6-month follow-up audit after 2 years of implementation, 36 of 39 patients were treated within 48 hours. This was significantly different to the time to surgery seen in the 12 months prior to the redesign (P KPI has allowed a significant culture shift in the treatment of hip fractures in our institution in the months following its institution. Collaborative, multidisciplinary collaboration has facilitated a higher standard of care and demonstrated significant cost benefit.
Adsorption of the inulinase from Kluyveromyces marxianus NRRL Y-7571 on Streamline® DEAE resin
Y. Makino
2005-12-01
Full Text Available The enzyme inulinase is used to produce oligosaccharides and fructose, with up to 95% fructose in a single stage of inulina hydrolysis. With in the aim to purify the enzyme, studies on the conditions of enzyme adsorption in an expanded-bed column were conducted using phosphate and tris-HCl buffers. The inulinase used in this work was obtained from Kluyveromyces marxianus NRRL Y-7571 by fermentation in an industrial medium. Using the anionic resin Streamline DEAE, the adsorption equilibrium time was determined. It was observed that the adsorption isotherm follows the Langmuir model; the parameters for the maximum amount of adsorbed inulinase (Qm and the dissociation constant (k d were determined. With 0.05 M sodium phosphate buffer at pH 6.0, the parameter values 1428 UI/mL and 2 UI/mL with a correlation coefficient of 0.96 were obtained. For 0.02 M tris-HCl buffer at pH 7.5, the same parameters were 5000 UI/mL and 0.05 UI/mL with a correlation coefficient of 0.99. The best purification conditions for the fixed bed were shown to be a 0.4 M phosphate buffer with NaCl as eluter, a purification factor of 11.4, and a recovery yield of up to 79%.
An automated perfusion bioreactor for the streamlined production of engineered osteogenic grafts.
Ding, Ming; Henriksen, Susan S; Wendt, David; Overgaard, Søren
2016-04-01
A computer-controlled perfusion bioreactor was developed for the streamlined production of engineered osteogenic grafts. This system automated the required bioprocesses, from the initial filling of the system through the phases of cell seeding and prolonged cell/tissue culture. Flow through chemo-optic micro-sensors allowed to non-invasively monitor the levels of oxygen and pH in the perfused culture medium throughout the culture period. To validate its performance, freshly isolated ovine bone marrow stromal cells were directly seeded on porous scaffold granules (hydroxyapatite/β-tricalcium-phosphate/poly-lactic acid), bypassing the phase of monolayer cell expansion in flasks. Either 10 or 20 days after culture, engineered cell-granule grafts were implanted in an ectopic mouse model to quantify new bone formation. After four weeks of implantation, histomorphometry showed more bone in bioreactor-generated grafts than cell-free granule controls, while bone formation did not show significant differences between 10 days and 20 days of incubation. The implanted granules without cells had no bone formation. This novel perfusion bioreactor has revealed the capability of activation larger viable bone graft material, even after shorter incubation time of graft material. This study has demonstrated the feasibility of engineering osteogenic grafts in an automated bioreactor system, laying the foundation for a safe, regulatory-compliant, and cost-effective manufacturing process. © 2015 Wiley Periodicals, Inc.
Streamlining gene expression analysis: integration of co-culture and mRNA purification.
Berry, Scott M; Singh, Chandresh; Lang, Jessica D; Strotman, Lindsay N; Alarid, Elaine T; Beebe, David J
2014-02-01
Co-culture of multiple cell types within a single device enables the study of paracrine signaling events. However, extracting gene expression endpoints from co-culture experiments is laborious, due in part to pre-PCR processing of the sample (i.e., post-culture cell sorting and nucleic acid purification). Also, a significant loss of nucleic acid may occur during these steps, especially with microfluidic cell culture where lysate volumes are small and difficult to access. Here, we describe an integrated platform for performing microfluidic cell culture and extraction of mRNA for gene expression analysis. This platform was able to recover 30-fold more mRNA than a similar, non-integrated system. Additionally, using a breast cancer/bone marrow stroma co-culture, we recapitulated stromal-dependent, estrogen-independent growth of the breast cancer cells, coincident with transcriptional changes. We anticipate that this platform will be used for streamlined analysis of paracrine signaling events as well as for screening potential drugs and/or patient samples.
Streamline integration as a method for two-dimensional elliptic grid generation
Wiesenberger, Matthias; Einkemmer, Lukas
2016-01-01
We propose a new numerical algorithm to construct a structured numerical grid of a doubly connected domain that is bounded by the contour lines of a given function. It is based on the integration of the streamlines of the two vector fields that form the basis of the coordinate system. These vector fields are either built directly from the given function or from the solution of a suitably chosen elliptic equation (which can be solved once an initial grid has been constructed). We are able to construct conformal, orthogonal and curvilinear coordinates. The method is parallelizable and the metric elements can be computed with high accuracy. Furthermore, it is easy to implement as only the integration of well-behaved ordinary differential equations and the inversion of a linear elliptic equation are required. All our grids are orthogonal to the boundary of the domain, which is the major advantage over previously suggested grids. We assess the quality of our grids with the solution of an elliptic equation and the ...
Effectiveness of streamlined admissions to methadone treatment: a simplified time-series analysis.
Dennis, M L; Ingram, P W; Burks, M E; Rachal, J V
1994-01-01
Increasing the availability of, and streamlining the admissions process to, methadone treatment have consistently been the focus of national plans to address the acquired immune deficiency syndrome (AIDS) epidemic. This article uses simplified time-series analysis to evaluate one of the first methadone treatment Waiting List Reduction Demonstration Grants. The demonstration grant significantly increased both the number of people requesting intake appointments from 35 to 100 per month and the percentage of kept appointments from 33% to 54%. An additional 100 slots (an entire year's waiting list) were filled in fewer than three months and actually resulted in a net increase in the length of the waiting list. Relative to the preceding two years, new clients during the grant period were significantly more likely to be 41 or older, African-American, unemployed, daily opioid users, daily cocaine users, and dependent on public assistance to finance treatment. Controlling for the source of treatment financing (a case-mix adjustment), there were no significant changes in retention rates. The program's static client capacity rose from 310 prior to the grant to a peak of 449 during the grant, with a leveling to 410 after the grant. Given that it is clearly more humane and less expensive to treat people who want treatment rather than wait for them to commit a crime and be arrested or even executed, this study strongly suggests the need to make more treatment available on demand.
Streamlining the Design-to-Build Transition with Build-Optimization Software Tools.
Oberortner, Ernst; Cheng, Jan-Fang; Hillson, Nathan J; Deutsch, Samuel
2017-03-17
Scaling-up capabilities for the design, build, and test of synthetic biology constructs holds great promise for the development of new applications in fuels, chemical production, or cellular-behavior engineering. Construct design is an essential component in this process; however, not every designed DNA sequence can be readily manufactured, even using state-of-the-art DNA synthesis methods. Current biological computer-aided design and manufacture tools (bioCAD/CAM) do not adequately consider the limitations of DNA synthesis technologies when generating their outputs. Designed sequences that violate DNA synthesis constraints may require substantial sequence redesign or lead to price-premiums and temporal delays, which adversely impact the efficiency of the DNA manufacturing process. We have developed a suite of build-optimization software tools (BOOST) to streamline the design-build transition in synthetic biology engineering workflows. BOOST incorporates knowledge of DNA synthesis success determinants into the design process to output ready-to-build sequences, preempting the need for sequence redesign. The BOOST web application is available at https://boost.jgi.doe.gov and its Application Program Interfaces (API) enable integration into automated, customized DNA design processes. The herein presented results highlight the effectiveness of BOOST in reducing DNA synthesis costs and timelines.
Numerical Investigation on Aerodynamic Force of Streamlined Box Girder with Uniform Air Suction
Tang Ke
2014-06-01
Full Text Available In the present study, the flow around a streamlined box girder with uniform air suction has been investigated numerically. Two-dimensional incompressible unsteady Reynolds averaged Navier-Stokes (URANS equations are solved in conjunction with the SST k −ω turbulence model in simulations. Taking the Great Belt Bridge girder as an example, cases of different suction positions on the girder section were discussed. The effect of the suction ratio and the angle of attack (AOA of wind also were investigated. The result showed that the aerodynamic drag force was influenced by the uniform suction through either upper surface or lower surface of the box girder. The larger the suction ratio was, the more the drag-reducing could be. The suction position and AOA had a comprehensive effect on the drag force. The vortex shedding frequency was also affected by air suction. For the aerodynamic lift force and moment, air suction showed no obvious influence. If necessary, using a combined suction scheme to reduce the aerodynamic drag force or to control the flow wake would be more efficient in engineering design.
Leyer D. V.
2016-05-01
Full Text Available Expansion and increasing of the Krasnodar region transport infrastructure during the construction of the Olympic facilities together with the new land development created a necessity for construction in the remote areas of landslide slopes with the complex engineering-geological conditions. Constructions of bored piles, jammed by in nondisplaceable soil are often used as one of the measures for the protection of surface rocks landslide movement and tightening the slope weak sections. Such constructive solution is often being considered the best, and sometimes the only acceptable solution. When designing engineering protection it is recommended to consider the use of a number of active protection activities, aimed at the landslide processes stabilization. However, in case of construction production impossibility due to terms of organization, it is necessary to provide passive protection which would secure that the landslide streamlines the construction. Currently, the mechanism of the soil landslides interaction with constructions of detached objects spot protection isn’t studied enough. Known methods adopt simplifications and assumptions which lead to definite significant errors in the design of slope protection structures. Security and reliability of such structures can only be achieved with the adoption of high factor of safety values. This leads to increased material consumption and labor input for the erection of defensive structures also reduces the economic efficiency of these structures. In addition the process of designing protective structures in the Krasnodar region is further complicated by fact that the landslide of construction area is mainly folded by flowing clay soils
Streamlining Building Efficiency Evaluation with DOE's Asset Score Preview
Goel, Supriya; Wang, Nora; Gonzalez, Juan; Horsey, Henry; Long, Nicholas
2016-08-26
Building Energy Asset Score (Asset Score), developed by the Pacific Northwest National Laboratory (PNNL) for the U.S. Department of Energy (DOE), is a tool to help building owners and managers assess the efficiency of a building's energy-related systems and encourage investment in cost-effective improvements. The Asset Score uses an EnergyPlus model to provide a quick assessment of building energy performance with minimum user inputs of building characteristics and identifies upgrade opportunities. Even with a reduced set of user inputs, data collection remains a challenge for wide-spread adoption, especially when evaluating a large number of buildings. To address this, Asset Score Preview was developed to allow users to enter as few as seven building characteristics to quickly assess their buildings before a more in-depth analysis. A streamlined assessment from Preview to full Asset Score provides an easy entry point and also enables users who manage a large number of buildings to screen and prioritize buildings that can benefit most from a more detailed evaluation and possible energy efficiency upgrades without intensive data collection.
Gao, Zhao-Ming
2014-04-01
"Candidatus Synechococcus spongiarum" is a cyanobacterial symbiont widely distributed in sponges, but its functions at the genome level remain unknown. Here, we obtained the draft genome (1.66 Mbp, 90% estimated genome recovery) of "Ca. Synechococcus spongiarum" strain SH4 inhabiting the Red Sea sponge Carteriospongia foliascens. Phylogenomic analysis revealed a high dissimilarity between SH4 and free-living cyanobacterial strains. Essential functions, such as photosynthesis, the citric acid cycle, and DNA replication, were detected in SH4. Eukaryoticlike domains that play important roles in sponge-symbiont interactions were identified exclusively in the symbiont. However, SH4 could not biosynthesize methionine and polyamines and had lost partial genes encoding low-molecular-weight peptides of the photosynthesis complex, antioxidant enzymes, DNA repair enzymes, and proteins involved in resistance to environmental toxins and in biosynthesis of capsular and extracellular polysaccharides. These genetic modifications imply that "Ca. Synechococcus spongiarum" SH4 represents a low-light-adapted cyanobacterial symbiont and has undergone genome streamlining to adapt to the sponge\\'s mild intercellular environment. 2014 Gao et al.
Christensen, Steen; Serbus, Laura Renee
2015-03-24
Two-component regulatory systems are commonly used by bacteria to coordinate intracellular responses with environmental cues. These systems are composed of functional protein pairs consisting of a sensor histidine kinase and cognate response regulator. In contrast to the well-studied Caulobacter crescentus system, which carries dozens of these pairs, the streamlined bacterial endosymbiont Wolbachia pipientis encodes only two pairs: CckA/CtrA and PleC/PleD. Here, we used bioinformatic tools to compare characterized two-component system relays from C. crescentus, the related Anaplasmataceae species Anaplasma phagocytophilum and Ehrlichia chaffeensis, and 12 sequenced Wolbachia strains. We found the core protein pairs and a subset of interacting partners to be highly conserved within Wolbachia and these other Anaplasmataceae. Genes involved in two-component signaling were positioned differently within the various Wolbachia genomes, whereas the local context of each gene was conserved. Unlike Anaplasma and Ehrlichia, Wolbachia two-component genes were more consistently found clustered with metabolic genes. The domain architecture and key functional residues standard for two-component system proteins were well-conserved in Wolbachia, although residues that specify cognate pairing diverged substantially from other Anaplasmataceae. These findings indicate that Wolbachia two-component signaling pairs share considerable functional overlap with other α-proteobacterial systems, whereas their divergence suggests the potential for regulatory differences and cross-talk.
Danillo Pinhal
Full Text Available Obtaining accurate species-specific landings data is an essential step toward achieving sustainable shark fisheries. Globally distributed sharpnose sharks (genus Rhizoprionodon exhibit life-history characteristics (rapid growth, early maturity, annual reproduction that suggests that they could be fished in a sustainable manner assuming an investment in monitoring, assessment and careful management. However, obtaining species-specific landings data for sharpnose sharks is problematic because they are morphologically very similar to one another. Moreover, sharpnose sharks may also be confused with other small sharks (either small species or juveniles of large species once they are processed (i.e., the head and fins are removed. Here we present a highly streamlined molecular genetics approach based on seven species-specific PCR primers in a multiplex format that can simultaneously discriminate body parts from the seven described sharpnose shark species commonly occurring in coastal fisheries worldwide. The species-specific primers are based on nucleotide sequence differences among species in the nuclear ribosomal internal transcribed spacer 2 locus (ITS2. This approach also distinguishes sharpnose sharks from a wide range of other sharks (52 species and can therefore assist in the regulation of coastal shark fisheries around the world.
An upwind super compact difference scheme for KdV-Burgers equation%一种求解 KdV-Burgers 方程的迎风超紧致差分格式
孙建安; 郭小霞; 贾伟
2015-01-01
In this paper , an upwind super compact difference scheme (USCD ) is proposed . The numerical characteristics of USCD are analyzed by using Fourier analysis , and compared with other upwind difference schemes and upwind compact difference schemes . According to analysis , it is found that USCD has better resolution and lower dissipation . Numerical solutions of the Burgers and KdV‐Burgers equations show that the USCD scheme has high‐order accuracy and is effective for long time evolution .%提出了一种迎风超紧致差分格式（USCD），利用Fourier分析方法对该格式的数值特性进行了分析，并与其他的迎风差分格式和迎风紧致差分格式做了对比。结果反映出USCD具有更好的分辨率和更低的耗散。通过对Burgers方程和KdV‐Burgers方程的数值模分析，进一步证实了USCD格式有更高的精度和对长时间演化问题的有效性。
Galerkin ﬁnite element methods for wave problems
T K Sengupta; S B Talla; S C Pradhan
2005-10-01
We compare here the accuracy, stability and wave propagation properties of a few Galerkin methods. The basic Galerkin methods with piecewise linear basis functions (called G1FEM here) and quadratic basis functions (called G2FEM) have been compared with the streamwise-upwind Petrov Galerkin (SUPG) method for their ability to solve wave problems. It is shown here that when the piecewise linear basis functions are replaced by quadratic polynomials, the stencils become much larger (involving ﬁve overlapping elements), with only a very small increase in spectral accuracy. It is also shown that all the three Galerkin methods have restricted ranges of wave numbers and circular frequencies over which the numerical dispersion relation matches with the physical dispersion relation - a central requirement for wave problems. The model one-dimensional convection equation is solved with a very ﬁne uniform grid to show the above properties. With the help of discontinuous initial condition, we also investigate the Gibbs’ phenomenon for these methods.
Enjilela, Vali; Salimi, Davood; Tavasoli, Ali; Lotfi, Mohsen
2016-02-01
In the present work, the meshless local Petrov-Galerkin vorticity-stream function (MLPG-VF) method is extended to solve two-dimensional laminar fluid flow and heat transfer equations for high Reynolds and Rayleigh numbers. The characteristic-based split (CBS) scheme which uses unity test function is employed for discretization, and the moving least square (MLS) method is used for interpolation of the field variables. Four test cases are considered to evaluate the present algorithm, namely lid-driven cavity flow with Reynolds numbers up to and including 104, flow over a backward-facing step at Reynolds number of 800, natural convection in a square cavity for Rayleigh numbers up to and including 108, and natural convection in a concentric square outer cylinder and circular inner cylinder annulus for Rayleigh numbers up to and including 107. In each case, the result obtained using the proposed algorithm is either compared with the results from the literatures or with those obtained using conventional numerical techniques. The present algorithm shows stable results at lower or equal computational cost compared to the other upwinding schemes usually employed in the MLPG method. Close agreements between the compared results as well as higher accuracy of the proposed method show the ability of this stabilized algorithm.
Holland, Thomas L; Mikita, Stephen; Bloom, Diane; Roberts, Jamie; McCall, Jonathan; Collyar, Deborah; Santiago, Jonas; Tiernan, Rosemary; Toerner, Joseph
2016-01-01
Objectives To explore patient, caregiver and physician perceptions and attitudes regarding the balance of benefit and risk in using antibacterial drugs developed through streamlined development processes. Design Semistructured focus groups and in-depth interviews were conducted to elicit perceptions and attitudes about the use of antibacterial drugs to treat multidrug-resistant infections. Participants were given background information about antibiotic resistance, streamlined drug development programmes and FDA drug approval processes. Audio recordings of focus groups/interviews were reviewed and quotes excerpted and categorised to identify key themes. Participants Two primary stakeholder groups were engaged: one comprising caregivers, healthy persons and patients who had recovered from or were at risk of resistant infection (N=67; 11 focus groups); and one comprising physicians who treat resistant infections (N=23). Results Responses from focus groups/interviews indicated widespread awareness among patients/caregivers and physicians of the seriousness of the problem of antibacterial resistance. Both groups were willing to accept a degree of uncertainty regarding the balance of risk and benefit in a new therapy where a serious unmet need exists, but also expressed a desire for rigorous monitoring and rapid, transparent reporting of safety/effectiveness data. Both groups wanted to ensure that >1 physician had input on whether to treat patients with antibiotics developed through a streamlined process. Some patients/caregivers unfamiliar with exigencies of critical care suggested a relatively large multidisciplinary team, while physicians believed individual expert consultations would be preferable. Both groups agreed that careful oversight and stewardship of antibacterial drugs are needed to ensure patient safety, preserve efficacy and prevent abuse. Conclusions Groups comprising patients/caregivers and physicians were aware of serious issues posed by resistant
Pham, Minh D.; Ting-Chun Wen; Hung-Cheng Li; Pei-Hsuan Hsieh; Yet-Ran Chen; Huan-Cheng Chang; Chau-Chung Han
2016-01-01
While mass spectrometry (MS) plays a key role in proteomics research, characterization of membrane proteins (MP) by MS has been a challenging task because of the presence of a host of interfering chemicals in the hydrophobic protein extraction process, and the low protease digestion efficiency. We report a sample preparation protocol, two-phase separation with Triton X-100, induced by NaCl, with coomassie blue added for visualizing the detergent-rich phase, which streamlines MP preparation fo...
el-Masry, O A; Feuerstein, I A; Round, G F
1978-10-01
Flow conditions in four models representing the aortic bifurcation, iliac bifuraction, and a renal artery branch were investigated at volumetric flow rates corresponding to Reynolds numbers from 1000 to 4000 over the complete range of flow division between daughter vessels. Qualitative flow streamline patterns and quantitative definition of those flow conditions leading to disturbed flow (flow separation ) were determined primarily at steady flow with a limited set of pulsatie experiments. Under conditions of no flow separation, common characteristic streamline patterns not parallel to the center lines of parent or daughter tubes were found for all models. These effects were accentuated with increasing Reynolds number. Flow separation was inducible through alteration of flow division between daughter vessels or by an increase in flow rate. Each of the four models had distinct combinations of flow division ratio and flow rate which gave: (1) no flow separation, (2) flow separation at the outside of the right daughter tube, and (3) flow separation at the outside of the left daughter tube. Models representing the renal artery also had regions of simultaneous left- and righthand separation on the outside of their daughter tubes. The separated flows observed here displayed streamlines forming an open vortex with flows entering and leaving. These regions, which occur only at distinct combinations of flow rate and flow division, may be key centers where platelet aggregates may form, release constituents, and cause vessel injury.
种山
2011-01-01
基于传统的Van Leer格式提出了一种改进的Van Leer(NVL)格式,解决了Van Leer格式在低马赫数下数值耗散过大,不能求解有粘流场等问题,同时保持Van Leer格式的计算效率.通过二维平板流动算例比较了NVL格式与传统Van Leer格式的数值耗散程度,并以NACA0012翼型的亚声速和跨声速流场以及M6机翼的跨声速流场求解为算例,与Roe格式和传统Van Leer格式进行比较,进一步验证了NVL格式的低耗散性和高效性.%Traditional Van Leer scheme cant be used to resolve viscous flow problems at low Mach number because of its high numerical dissipation. A new upwind discretization scheme new Van Leer (NVL)is proposed to solve this problem. The umerical discretizations of NVL Scheme and traditional VanLeer Scheme are compared by taking the calculation example of Blasiu' s flow. And by taking three numerical experiments including subsonic and transonic flows over NACA0012 airfoil and transonic flows over M6 wing, Roe and traditional Van Leer scheme are compared to illustrate the performance of this new approach. The results indicate that NVL scheme is characterized with low discreization and high efficiency.
Allen, G.; O'Shea, S.; Muller, J.; Jones, B.; O'Sullivan, D.; Lee, J. D.; Bauguitte, S.; Gallagher, M. W.; Percival, C.; Barratt, B.; McQuaid, J. B.; Illingworth, S.
2013-12-01
This study presents airborne in situ and remote sensing measurements recorded during July and August 2012, across the period of the London 2012 Summer Olympics and simultaneous with the Clear air for London (ClearfLo) ground-based measurement and modelling campaign. Through long-term (2-year) and intensive observation periods (Winter 2011 and Summer 2012), the ClearfLo programme aims to better understand emissions, as well as the chemical, dynamical and micro-meteorological processes which modulate air quality in the London urban environment - an important risk factor for both acute and chronic health effects. The work presented here focuses on two contrasting case studies within the summer ClearfLo period: 30 July 2012 and 9 August 2012, representing relatively clean background and polluted background cases, respectively, and characterised by well-mixed Atlantic westerly maritime inflow in the former and stagnant air (high pressure) in the latter. Measurements of CO, CO2, CH4, N2O, O3, HCN, and other gases measured on board the UK Facility for Airborne Atmospheric Measurement (FAAM) BAe-146 aircraft will be presented and interpreted, with emphasis on observed concentration gradients and tracer-tracer correlations as well as airmass vertical structure and airmass history upwind and downwind of central London in each case. By applying a simple advective model and making use of vertically resolved thermodynamic and composition data, we are able to derive emission strengths for these gases that are representative of the total enclosed surface area. Example emissions for these two cases range between 6x105 kg(C)/hr and 9x105 kg(C)/hr for CO2, and ~0.6x105 kg(C)/hr for CH4. This airborne sampling methodology highlights the unique utility of aircraft measurements to routinely and climatologically characterise emissions from area sources such as cities, and points to future missions to target localised hotspots and distributed point sources.
Improving and streamlining the workflow in the graphic arts and printing industry
Tuijn, Chris
2003-01-01
In order to survive in the economy of today, an ever-increasing productivity is required from all the partners participating in a specific business process. This is not different for the printing industry. One of the ways to remain profitable is, on one hand, to reduce costs by automation and aiming for large-scale projects and, on the other hand, to specialize and become an expert in the area in which one is active. One of the ways to realize these goals is by streamlining the communication of the different partners and focus on the core business. If we look at the graphic arts and printing industry, we can identify different important players that eventually help in the realization of printed material. For the printing company (as is the case for any other company), the most important player is the customer. This role can be adopted by many different players including publishers, companies, non-commercial institutions, private persons etc. Sometimes, the customer will be the content provider as well but this is not always the case. Often, the content is provided by other organizations such as design and prepress agencies, advertising companies etc. In most printing organizations, the customer has one contact person often referred to as the CSR (Customers Service Representative). Other people involved at the printing organization include the sales representatives, prepress operators, printing operators, postpress operators, planners, the logistics department, the financial department etc. In the first part of this article, we propose a solution that will improve the communication between all the different actors in the graphic arts and printing industry considerably and will optimize and streamline the overall workflow as well. This solution consists of an environment in which the customer can communicate with the CSR to ask for a quote based on a specific product intent; the CSR will then (after the approval from the customer's side) organize the work and brief
Determining the tube bundle streamlining critical parameters using the numerical experiment method
Kaplunov, S. M.; Val'es, N. G.; Samolysov, A. V.; Marchevskaya, O. A.
2015-08-01
The article is devoted to development and application of mathematical models describing the most dangerous mechanisms through which vibrations are excited in tube bundles and blunt cylindrically shaped structures, and to development of reliable calculation methods for describing these models, which would make it possible to obtain prompt data for designing and subsequent operation of the considered structural elements. For solving such problems, a comprehensive approach is required, which should be based on a combined use of numerical experiments on computers and experimental investigations on full-scale equipment. The authors have developed a procedure for numerically investigating the hydrodynamic forces arising during stalled streamlining and the tube bundle vibrations caused by these forces. The procedure is based on using the developed mathematical model describing fluid-elastic excitation of vibrations in a bundle of elastic tubes placed in external cross flow. The problem of studying fluid-elastic excitation is brought to stability analysis, which is carried out with the assumption about a linear behavior of destabilizing forces for undisturbed state of elastic tubes. A theoretical investigation of the developed mathematical model was carried out, from which the necessary and sufficient condition of system stability has been obtained in terms of system dimensionless parameters (mass, damping, and velocity). An algorithm for numerically determining the matrices of linear hydrodynamic coupling coefficients for particular tube bundles is developed. The validity of the algorithm and the computer programs developed on its basis are checked by comparing the results of test calculations with the bank of known experimental data. A procedure is proposed for determining the matrices of linear hydrodynamic coupling coefficients in bundles having a regular layout of their cross section and a large number of tubes through calculating these matrices for a relatively small
Vortex Generators in a Streamline-Traced, External-Compression Supersonic Inlet
Baydar, Ezgihan; Lu, Frank K.; Slater, John W.; Trefny, Charles J.
2017-01-01
Vortex generators within a streamline-traced, external-compression supersonic inlet for Mach 1.66 were investigated to determine their ability to increase total pressure recovery and reduce total pressure distortion. The vortex generators studied were rectangular vanes arranged in counter-rotating and co-rotating arrays. The vane geometric factors of interest included height, length, spacing, angle-of-incidence, and positions upstream and downstream of the inlet terminal shock. The flow through the inlet was simulated numerically through the solution of the steady-state, Reynolds-averaged Navier-Stokes equations on multi-block, structured grids using the Wind-US flow solver. The vanes were simulated using a vortex generator model. The inlet performance was characterized by the inlet total pressure recovery and the radial and circumferential total pressure distortion indices at the engine face. Design of experiments and statistical analysis methods were applied to quantify the effect of the geometric factors of the vanes and search for optimal vane arrays. Co-rotating vane arrays with negative angles-of-incidence positioned on the supersonic diffuser were effective in sweeping low-momentum flow from the top toward the sides of the subsonic diffuser. This distributed the low-momentum flow more evenly about the circumference of the subsonic diffuser and reduced distortion. Co-rotating vane arrays with negative angles-of-incidence or counter-rotating vane arrays positioned downstream of the terminal shock were effective in mixing higher-momentum flow with lower-momentum flow to increase recovery and decrease distortion. A strategy of combining a co-rotating vane array on the supersonic diffuser with a counter-rotating vane array on the subsonic diffuser was effective in increasing recovery and reducing distortion.
New vectors for simple and streamlined CRISPR-Cas9 genome editing in Saccharomyces cerevisiae.
Laughery, Marian F; Hunter, Tierra; Brown, Alexander; Hoopes, James; Ostbye, Travis; Shumaker, Taven; Wyrick, John J
2015-12-01
Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 technology is an important tool for genome editing because the Cas9 endonuclease can induce targeted DNA double-strand breaks. Targeting of the DNA break is typically controlled by a single-guide RNA (sgRNA), a chimeric RNA containing a structural segment important for Cas9 binding and a 20mer guide sequence that hybridizes to the genomic DNA target. Previous studies have demonstrated that CRISPR-Cas9 technology can be used for efficient, marker-free genome editing in Saccharomyces cerevisiae. However, introducing the 20mer guide sequence into yeast sgRNA expression vectors often requires cloning procedures that are complex, time-consuming and/or expensive. To simplify this process, we have developed a new sgRNA expression cassette with internal restriction enzyme sites that permit rapid, directional cloning of 20mer guide sequences. Here we describe a flexible set of vectors based on this design for cloning and expressing sgRNAs (and Cas9) in yeast using different selectable markers. We anticipate that the Cas9-sgRNA expression vector with the URA3 selectable marker (pML104) will be particularly useful for genome editing in yeast, since the Cas9 machinery can be easily removed by counter-selection using 5-fluoro-orotic acid (5-FOA) following successful genome editing. The availability of new vectors that simplify and streamline the technical steps required for guide sequence cloning should help accelerate the use of CRISPR-Cas9 technology in yeast genome editing.
Dowling, Tom; Möller, Per; Greenwood, Sarah; Spagnolo, Matteo; Åkesson, Maria; Fraser, Stephen; Hughs, Anna; Clark, Chris
2016-04-01
Much work has qualitatively shown that there appears to be a relationship between the morphology of streamlined subglacial bedforms (drumlinoids) and the geological/geographical environment in which said bedforms are located upon, particularly in terms of bedrock influence. However, the one quantitative study that has been carried out on this connectivity (Greenwood and Clark, 2010) found that there appears to be a connection between bedrock type and morphology only at a local scale. At a regional scale the most important geological factor seemed to be the properties of the substrate, usually till. In order to investigate these connections further, self-organising maps (SOM) are used to investigate the role of contextual geology/geography in drumlinoid morphology. The SOM method allows the statistical exploration of data that cannot normally be evaluated by traditional means; categorical data (e.g. bedrock type) can be used in the same analysis as continuous/vector data (e.g. drift depth). Here, three large morphological data sets from Sweden (20 041), Britain (36 104) and Ireland (13 454) are combined with bedrock type, drift depth, basal elevation and distance to esker to see if there are any relationships to be found between them. The results indicate that there are pervasive, statistically significant, and weak to very weak correlations between contextual geological/geographical factors and drumlinoid morphology. The most important contextual factor appears to be 'drift depth', followed by 'distance to esker'. Therefore, models of drumlinoid formation and any efforts to use such features for palaeo-ice reconstruction must take into account the geological and geographical environment in which they are situated. The logical extension of this is that models of ice-sheet growth and retreat must also take into account and be sensitive to the type of substratum present beneath the ice. Further research into the effect of drift properties on the flow of ice is needed.
Fisher Alfred L
2008-12-01
Full Text Available Abstract Background The nematode Caenorhabditis elegans has emerged as a powerful system to study biologic questions ranging from development to aging. The generation of transgenic animals is an important experimental tool and allows use of GFP fusion proteins to study the expression of genes of interest or generation of epitope tagged versions of specific genes. Transgenes are often generated by placing a promoter upstream of a reporter gene or cDNA. This often produces a representative expression pattern, but important exceptions have been observed. To better capture the genuine expression pattern and timing, several investigators have modified large pieces of DNA carried by BACs or fosmids for use in the construction of transgenic animals via recombineering. However, these techniques are not in widespread use despite the advantages when compared to traditional approaches. Additionally, some groups have encountered problems with employing these techniques. Hence, we sought identify ways to improve the simplicity and reliability of the procedure. Results We describe here several important modifications we have made to existing protocols to make the procedure simpler and more robust. Among these are the use of galK gene as a selection marker for both the positive and negative selection steps in recombineering, the use of R6K based plasmids which eliminate the need for extensive PCR product purification, a means to integrate the unc-119 marker on to the fosmid backbone, and placement of homology arms to commonly used GFP and TAP fusion genes flanking the galK cassette which reduces the cost of oligos by 50%. Conclusion We have made several significant changes that allow the production of C. elegans transgenes from a commercially available fosmid library in a robust and streamlined manner. These changes make the technique more attractive especially to small academic labs unfamiliar with recombineering.
Zhang, Cindy; Cao, June; Kenyon, James R; Panzica-Kelly, Julieta M; Gong, Lei; Augustine-Rauch, Karen
2012-06-01
This study describes a novel rat whole embryo culture (rWEC) teratogenicity assay that applies a simplified experimental design and statistical prediction model, resulting in reduced animal requirements and increased throughput with low prediction error rate for classifying teratogenic potential of compounds. A total of 70 compounds (38 teratogens and 32 nonteratogens) were evaluated, and the prediction model was generated from a dataset of 59 compounds. The rWEC assay requires only one test concentration (1μM) and three structural endpoints (group average morphological scores of spinal cord, heart, and number of somite pairs), which are used in a recursive partition model for classifying teratogenic liability. The model fitting concordance between the WEC assay and in vivo outcome was 83% with a standard deviation (SD) of 4.9%. The predictivity for future compounds was evaluated by using two statistical methods. Fivefold cross-validation estimated the predictivity of this model at 73% (SD 5.8%). A second estimation of predictivity was obtained from an independent test set of 11 compounds that were not used to build the prediction model and reached 82% (SD 11.6%). The overall estimate for prediction concordance is 74% (SD 5.2%). There is no statistically significant difference (p value > 0.50) in the predictivity between this model and the model supporting European Center for the Validation of Alternative Methods WEC assay with predictivity of 80% (SD 10.6%). Overall, the streamlined WEC assay is estimated to reduce animal use and operational costs by more than 50%. It substantially improves results turnaround with no loss of predictivity.
Streamlined protein expression and purification using cleavable self-aggregating tags
Zhou Bihong
2011-06-01
Full Text Available Abstract Background Recombinant protein expression and purification remains a fundamental issue for biotechnology. Recently we found that two short self-assembling amphipathic peptides 18A (EWLKAFYEKVLEKLKELF and ELK16 (LELELKLKLELELKLK can induce the formation of active protein aggregates in Escherichia coli (E. coli, in which the target proteins retain high enzymatic activities. Here we further explore this finding to develop a novel, facile, matrix-free protein expression and purification approach. Results In this paper, we describe a streamlined protein expression and purification approach by using cleavable self-aggregating tags comprising of one amphipathic peptide (18A or ELK16 and an intein molecule. In such a scheme, a target protein is first expressed as active protein aggregate, separated by simple centrifugation, and then released into solution by intein-mediated cleavage. Three target proteins including lipase A, amadoriase II and β-xylosidase were used to demonstrate the feasibility of this approach. All the target proteins released after cleavage were highly active and pure (over 90% in the case of intein-ELK16 fusions. The yields were in the range of 1.6-10.4 μg/mg wet cell pellet at small laboratory scale, which is comparable with the typical yields from the classical his-tag purification, the IMPACT-CN system (New England Biolabs, Beverly, MA, and the ELP tag purification scheme. Conclusions This tested single step purification is capable of producing proteins with high quantity and purity. It can greatly reduce the cost and time, and thus provides application potentials for both industrial scale up and laboratorial usage.
White, K. D.; Friedman, D.; Schechter, J.; Foley, P.; Mueller, C.; Baker, B.; Huber, M.; Veatch, W.
2016-12-01
Observed and projected impacts of climate change are pronounced on the hydrologic cycle because of the sensitivity of hydroclimatic variables to changes in temperature. Well-documented climate change impacts to the hydrologic cycle include increases in extreme heat conditions, coastal flooding, heavy precipitation, and drought frequency and magnitude, all of which can combine in surprising ways to pose regionally varying threats to public health and safety, ecosystem functions, and the economy. Climate preparedness and resilience activities are therefore necessary for water infrastructure which provides flood risk reduction, navigation, water supply, ecosystem restoration, and hydropower services. Because this water infrastructure entails long lifetimes, up to or beyond 100 years, and significant public investment, accurate and timely information about climate impacts over both the near-and far-term is required to plan and implement climate preparedness and resilience measures. Engineers are natural translators of science into actionable information to support this type of decision-making, because they understand both the important physical processes and the processes, laws, standards, and criteria required for the planning and design of public infrastructure. Though engineers are capable of the data management activities needed to ingest, transform, and prepare climate information for use in these decisions, the US Army Corps of Engineers (USACE) has chosen to emphasize analysis of information over data management. In doing so, the USACE is developing and using web tools with visualization capabilities to streamline climate preparedness and resilience planning and implementation while ensuring repeatable analytical results nationally. Examples discussed here include calculation of sea level change, including a comparison of mean sea level and other tidal statistics against scenarios of change; detection of abrupt and slowly varying nonstationarities in observed
Gregg, C. E.; Sorensen, J. H.; Vogt Sorensen, B.; Whitmore, P.; Johnston, D. M.
2016-12-01
format and expanded punctuation, a practice which the NWS first started in 2010. Here we describe our application of a modification of the warning message metric to develop new streamlined messages using mixed-case text. These messages reflect current state-of-the-art knowledge on warning message effectiveness.
袁益让; 李长峰
2012-01-01
可压缩可混溶油、水三维渗流动边值问题的研究,对重建盆地发育中油气资源运移、聚集的历史和评估油气资源的勘探与开发有重要的价值,其数学模型是一组非线性耦合偏微分方程组的动边值问题.该文对有界域的动边值问题提出一类新的二阶修正迎风差分格式,应用区域变换、变分形式、能量方法、差分算子乘积交换性理论、高阶差分算子的分解、微分方程先验估计的理论和技巧,得到了最佳l2误差估计结果.该方法已成功应用到油资评估的数值模拟中.它对这一领域的模型分析,数值方法和软件研制均有重要的价值.%The research of the three-dimensional compressible miscible (oil and water) displace-ment problem with moving boundary values is of great value to the history of oil-gas transport and accumulation in basin evolution, as well as to the rational evaluation in prospecting and exploiting oil-gas resources. The mathematical model can be described as a coupled system of nonlinear partial differential equations with moving boundary values. For a generic case of three-dimensional bounded region, the authors put forward a kind of upwind finite difference schemes and make use the calculus of variations, the change of variables and the theory of a priori estimates and techniques. Optimal order estimates in l2 norm are derived for the errors in approximate solutions. The research is important both theoretically and practically for model analysis in the field, model numerical method and software development. Thus, the well-known problem is solved.
改进的二维三阶半离散中心迎风格式%Modified Two Dimensional Third-order Semi-discrete Central-upwind Scheme
侯天相; 纪珍
2012-01-01
对二维三阶半离散中心迎风格式中的权函数给出了简化改进.在保持格式精度的基础上,改进后的权函数在二维情况下具有更加简单直接的结构而且严格非负.该改进方法得到的格式仍然具有半离散中心迎风格式的优点,同时保持了重构函数的非振性.时间离散采用保持强稳定性的三阶Runge-Kutta方法,并利用四阶Lax-Wendroff（L-W）格式计算磁流体算例中的磁场散度.用该修正格式计算了二维磁流体数值算例,得到高精度无振荡的结果,验证了此方法的有效性.%The semi-discrete central-upwind scheme is a new Godunov type numerical method which is developed in 1990s. The scheme is widely used in the computational fluid dynamics and its advantages include the simple calculation process, the high calculation precision and so on. But for the third-order scheme, the positivity of the weight function and the non-oscillation of the WENO type reconstruction function in every direction cannot be preserved in two dimensional problems. In this article, a simple, direct modification is taken to the weight function of the two dimensional third-order semi-discrete central-upwind scheme. The modified weight function will keep the posi- tivity all the time while the accuracy of the semi-discrete central-upwind method is preserved. The revised scheme still has the advantages of central-upwind schemes and it keeps the non-oscillation of reconstruction. To explore the potential capability of application of this reformation of weight func- tion, two Magnetohydrodynamics （MHD） problems are simulated. In simulations, the third order Runge-Kutta method is used to solve the time evolution and the divergence of magnetic field was calculated by fourth-order Lax-Wendroff （L-W） scheme. All the numerical results demonstrate the modified scheme can solve the MHD equations stably, get high resolution and non-oscillatory results, keep the positivity of the weight
Anca Chiriac
Full Text Available BACKGROUND: Pluripotent stem cells produce tissue-specific lineages through programmed acquisition of sequential gene expression patterns that function as a blueprint for organ formation. As embryonic stem cells respond concomitantly to diverse signaling pathways during differentiation, extraction of a pro-cardiogenic network would offer a roadmap to streamline cardiac progenitor output. METHODS AND RESULTS: To resolve gene ontology priorities within precursor transcriptomes, cardiogenic subpopulations were here generated according to either growth factor guidance or stage-specific biomarker sorting. Innate expression profiles were independently delineated through unbiased systems biology mapping, and cross-referenced to filter transcriptional noise unmasking a conserved progenitor motif (55 up- and 233 down-regulated genes. The streamlined pool of 288 genes organized into a core biological network that prioritized the "Cardiovascular Development" function. Recursive in silico deconvolution of the cardiogenic neighborhood and associated canonical signaling pathways identified a combination of integrated axes, CXCR4/SDF-1, Flk-1/VEGF and BMP2r/BMP2, predicted to synchronize cardiac specification. In vitro targeting of the resolved triad in embryoid bodies accelerated expression of Nkx2.5, Mef2C and cardiac-MHC, enhanced beating activity, and augmented cardiogenic yield. CONCLUSIONS: Transcriptome-wide dissection of a conserved progenitor profile thus revealed functional highways that coordinate cardiogenic maturation from a pluripotent ground state. Validating the bioinformatics algorithm established a strategy to rationally modulate cell fate, and optimize stem cell-derived cardiogenesis.
Xu, Gang; Liang, Xifeng; Yao, Shuanbao; Chen, Dawei; Li, Zhiwei
2017-01-01
Minimizing the aerodynamic drag and the lift of the train coach remains a key issue for high-speed trains. With the development of computing technology and computational fluid dynamics (CFD) in the engineering field, CFD has been successfully applied to the design process of high-speed trains. However, developing a new streamlined shape for high-speed trains with excellent aerodynamic performance requires huge computational costs. Furthermore, relationships between multiple design variables and the aerodynamic loads are seldom obtained. In the present study, the Kriging surrogate model is used to perform a multi-objective optimization of the streamlined shape of high-speed trains, where the drag and the lift of the train coach are the optimization objectives. To improve the prediction accuracy of the Kriging model, the cross-validation method is used to construct the optimal Kriging model. The optimization results show that the two objectives are efficiently optimized, indicating that the optimization strategy used in the present study can greatly improve the optimization efficiency and meet the engineering requirements.
Sharma, A.; Leo, L. S.; Thompson, M. Y.; Di Sabatino, S.; Fernando, H. J.; Zhong, Q.; Wang, H.
2015-12-01
It is well known that, when a stably stratified flow with approach velocity U and buoyancy frequency N flows over an obstacle of height h, the low-level flow goes around the object while the rest flows over it for low F = U / N h. The streamline that separates the two types of flow is the dividing streamline, and the prediction of its height Hs is of great practical interest. Sheppard (1956) provided the analytical solution Hs = h (1 - F) and, because of its practical utility, the formula continues to be largely employed, notwithstanding the criticism it has attracted because of certain underlying assumptions, viz., 1) the crude approximation of constant N and uniform approach velocity U, which is unrealistic for atmospheric flows; 2) the incorrect assumption of a complete balance between kinetic and potential energy at the mountain summit, which neglects the energy contributions of the perturbation pressure field as well as viscous dissipation adjacent to the hill surface. In this study, the first limitation is addressed by considering a logarithmic approach velocity profile but with constant N. A modified logarithmic velocity profile for stably stratified flows is proposed, and an analytical solution is obtained for Hs in terms of Lambert-W functions. Results are tested against smoke visualization experiments and related field measurements made during the Mountain Terrain Atmospheric Modeling and Observations (MATERHORN) Program. Some of the assumptions and perceived violations of them are tested using laboratory experiments conducted in a stratified water channel.
Pierzga, M. J.
1980-05-01
To verify the results of a streamline curvature numerical analysis method, an investigation has been conducted in which comparisons are made between analytical and experimental data of an axial flow fan. Using loss model calculations to determine the proper outlet flow deviation angles, the flow field in the hub to tip plane of the turbomachine was calculated. These deviation angle calculations allow the inviscid streamline curvature (SLC) analysis to model a real fluid with viscous losses. The verification of this calculated flow field is the primary objective of the investigation; however, in addition to the hub to tip flow field, the numerical analysis of the blade-to-blade flow field was also investigated in some detail. To verify the accuracy of the numerical results, detailed flow surveys were conducted upstream and downstream of the test rotor of the axial flow fan. To obtain the necessary data to verify the blade-to-blade solution, internal blade row data were also collected. The internal blade row measurements were obtained by using a rotating circumferential traversing mechanism which was designed and implemented during this investigation. Along with these two sets of survey data, the static pressure distributions on the pressure and suction surfaces of the test rotor were also obtained.
Eyles, Nick; Doughty, Mike
2016-06-01
An extensive tract of glacially-streamlined terrain across a large part of Southern Ontario, Canada, is recognized as the footprint of the paleo-Ontario Ice Stream (OIS) within the easternmost Great Lakes sector of the last Laurentide Ice Sheet. The upstream part is a drumlinized and megagrooved 'hard bed' underlain by Cambro-Ordovician carbonates and sandstones. Subglacial plucking of jointed limestone on the lateral margins of drumlinized escarpment interfluves and rock drumlins generated a large flux of coarse debris within the ice base, recorded by sporadic spreads of hummocky rubble moraine. Downstream, the hard bed passes underneath a streamlined 'soft' bed of till-cored ('drift') drumlins and megaridges of the classic Peterborough and New York State drumlin fields. The boundary between the two bed types is a ~ 10 km wide 'mixed bed' of isolated drift drumlins resting on drumlinized rock suggesting a common erosional origin. Spatial variation in the geomorphology of ~ 2500 drift drumlins, indicates that megaridges are clones resulting from the erosion and dissection of larger parent drumlins. A large moraine system may mark the final collapse and melt of the ice stream, accompanying abrupt flow switching of its margin.
胡彦梅; 封建湖; 陈建忠
2014-01-01
对多车种LWR交通流模型，给出一种半离散中心迎风格式，该格式以五阶WENO⁃Z重构和半离散中心迎风数值通量为基础。 WENO⁃Z重构方法的引入提高了格式的精度，并保证格式具有基本无振荡的性质。时间的离散采用保持强稳定性的Runge⁃Kutta方法。通过数值算例验证了格式的有效性。%A semi⁃discrete central⁃upwind scheme for multi⁃class Lighthill⁃Whitham⁃Richards ( LWR ) traffic flow model is presented. It combines improved fifth⁃order weighted essentially non⁃oscillatory ( WENO) reconstruction called WENO⁃Z with semi⁃discrete central⁃upwind numerical flux. WENO⁃Z reconstruction improves accuracy of solution with non⁃oscillatory property. Time integration is carried out with strong stability preserving Runge⁃Kutta method. Numerical results demonstrate the scheme is efficient.
Clerc, S
1998-07-01
In this work, the numerical simulation of fluid dynamics equations is addressed. Implicit upwind schemes of finite volume type are used for this purpose. The first part of the dissertation deals with the improvement of the computational precision in unfavourable situations. A non-conservative treatment of some source terms is studied in order to correct some shortcomings of the usual operator-splitting method. Besides, finite volume schemes based on Godunov's approach are unsuited to compute low Mach number flows. A modification of the up-winding by preconditioning is introduced to correct this defect. The second part deals with the solution of steady-state problems arising from an implicit discretization of the equations. A well-posed linearized boundary value problem is formulated. We prove the convergence of a domain decomposition algorithm of Schwartz type for this problem. This algorithm is implemented either directly, or in a Schur complement framework. Finally, another approach is proposed, which consists in decomposing the non-linear steady state problem. (author)
Balci, Adnan; Andersen, Morten; Thompson, M. C.
2015-01-01
for the eruption process, which can account for all observed changes in the Reynolds number range we consider. The bifurcation diagram complements previously analyzes such that the classification of topological bifurcations of flows close to no-slip walls with up to three parameters is now complete.......A vortex close to a no-slip wall gives rise to the creation of new vorticity at the wall. This vorticity may organize itself into vortices that erupt from the separated boundary layer. We study how the eruption process in terms of the streamline topology is initiated and varies in dependence...... of the Reynolds number Re. We show that vortex structures are created in the boundary layer for Re around 600, but that these disappear again without eruption unless Re > 1000. The eruption process is topologically unaltered for Re up to 5000. Using bifurcation theory, we obtain a topological phase space...
Laniak, G.
2013-12-01
21st century environmental problems are wicked and require holistic systems thinking and solutions that integrate social and economic knowledge with knowledge of the environment. Computer-based technologies are fundamental to our ability to research and understand the relevant systems and to provide assessors and decision makers with appropriate data, tools, and strategies. There are significant science and technology challenges being confronted in an effort to streamline the movement of knowledge from its research and experience-based sources to its decision endpoints. In this presentation we explore this continuum and attempt to articulate a holistic and coherent picture of the relationship among the myriad elements of the environmental problem solving landscape. This is done in the hope that this view will enhance the ability of all environmental stakeholders to express their individual contributions in a technological form that will be accessible and usable to the greater community.
Kupczik, Kornelius; Stark, Heiko; Mundry, Roger; Neininger, Fabian T; Heidlauf, Thomas; Röhrle, Oliver
2015-10-07
Skeletal muscle models are used to investigate motion and force generation in both biological and bioengineering research. Yet, they often lack a realistic representation of the muscle's internal architecture which is primarily composed of muscle fibre bundles, known as fascicles. Recently, it has been shown that fascicles can be resolved with micro-computed tomography (µCT) following staining of the muscle tissue with iodine potassium iodide (I2KI). Here, we present the reconstruction of the fascicular spatial arrangement and geometry of the superficial masseter muscle of a dog based on a combination of pattern recognition and streamline computation. A cadaveric head of a dog was incubated in I2KI and µCT-scanned. Following segmentation of the masseter muscle a statistical pattern recognition algorithm was applied to create a vector field of fascicle directions. Streamlines were then used to transform the vector field into a realistic muscle fascicle representation. The lengths of the reconstructed fascicles and the pennation angles in two planes (frontal and sagittal) were extracted and compared against a tracked fascicle field obtained through cadaver dissection. Both fascicle lengths and angles were found to vary substantially within the muscle confirming the complex and heterogeneous nature of skeletal muscle described by previous studies. While there were significant differences in the pennation angle between the experimentally derived and µCT-reconstructed data, there was congruence in the fascicle lengths. We conclude that the presented approach allows for embedding realistic fascicle information into finite element models of skeletal muscles to better understand the functioning of the musculoskeletal system.
A previously reported multiresidue method for the analysis of 11 important beta-lactams in bovine kidney has been further streamlined. The method is based on a simple extraction using acetonitrile-water (4:1, v/v), followed by dispersive solid-phase extraction clean-up with C18 sorbent, concentrati...
Möller, Per; Dowling, Thomas P. F.
2016-08-01
A flow set of close to 1000 drumlins has been mapped by means of LiDAR-derived digital elevation models and investigated by trenching. The area is situated on the SW part of the Närke plain and its surrounding uplands in south-central Sweden, which was deglaciated in the early Preboreal in a glacioaquatic setting. We find that there is considerable morphological difference in drumlin distribution patterns over crystalline basement areas compared to streamlined terrain over Palaeozoic sedimentary rock basement. The former area is characterized by thin Quaternary drift and the drumlins are all of the rock-cored type, built due to active deposition of sediment around obstacles to glacier flow. The latter area is characterized by deep Quaternary drift and the drumlins are more elongate and also larger in all dimensions, as compared to rock-cored drumlins. Irrespective of these geomorphological differences on local landscape scale we find that drumlin morphometric values remain part of a morphological continuum at the regional scale. Based on the internal sediment architecture as revealed in two cross-drumlin sections we find that the soft-cored drumlins were formed by compressional constructive deformation, along with excavational deformation along the flanks of the emerging drumlins, which shaped the separating troughs. Intermediate-type drumlins are those that demonstrate a coupling between underlying Palaeozoic sediment strata in areas of shallow drift sheet. These are the result of differing rheological response between incorporated sedimentary rock and a deforming bed below the ice-bed interface. An overall conclusion is that we find geomorphic and architectural compositional differences between the drumlins and the flowset they form. We can closely relate these differences to contextual geological variations with respect to basement type and drift depth. We argue that drumlin formation is better explained not by one single 'unifying' process but rather a set of
Dawood, Ban B; Lowe, Gillian C; Lordkipanidzé, Marie; Bem, Danai; Daly, Martina E; Makris, Mike; Mumford, Andrew; Wilde, Jonathan T; Watson, Steve P
2012-12-13
Light transmission aggregometry (LTA) is used worldwide for the investigation of heritable platelet function disorders (PFDs), but interpretation of results is complicated by the feedback effects of ADP and thromboxane A(2) (TxA(2)) and by the overlap with the response of healthy volunteers. Over 5 years, we have performed lumi-aggregometry on 9 platelet agonists in 111 unrelated research participants with suspected PFDs and in 70 healthy volunteers. Abnormal LTA or ATP secretion test results were identified in 58% of participants. In 84% of these, the patterns of response were consistent with defects in Gi receptor signaling, the TxA(2) pathway, and dense granule secretion. Participants with defects in signaling to Gq-coupled receptor agonists and to collagen were also identified. Targeted genotyping identified 3 participants with function-disrupting mutations in the P2Y(12) ADP and TxA(2) receptors. The results of the present study illustrate that detailed phenotypic analysis using LTA and ATP secretion is a powerful tool for the diagnosis of PFDs. Our data also enable subdivision at the level of platelet-signaling pathways and in some cases to individual receptors. We further demonstrate that most PFDs can be reliably diagnosed using a streamlined panel of key platelet agonists and specified concentrations suitable for testing in most clinical diagnostic laboratories.
Ruskova, Lenka; Raclavsky, Vladislav
2011-09-01
Routine medical microbiology diagnostics relies on conventional cultivation followed by phenotypic techniques for identification of pathogenic bacteria and fungi. This is not only due to tradition and economy but also because it provides pure culture needed for antibiotic susceptibility testing. This review focuses on the potential of High Resolution Melting Analysis (HRMA) of double-stranded DNA for future routine medical microbiology. Search of MEDLINE database for publications showing the advantages of HRMA in routine medical microbiology for identification, strain typing and further characterization of pathogenic bacteria and fungi in particular. The results show increasing numbers of newly-developed and more tailor-made assays in this field. For microbiologists unfamiliar with technical aspects of HRMA, we also provide insight into the technique from the perspective of microbial characterization. We can anticipate that the routine availability of HRMA in medical microbiology laboratories will provide a strong stimulus to this field. This is already envisioned by the growing number of medical microbiology applications published recently. The speed, power, convenience and cost effectiveness of this technology virtually predestine that it will advance genetic characterization of microbes and streamline, facilitate and enrich diagnostics in routine medical microbiology without interfering with the proven advantages of conventional cultivation.
Pierzga, M. J.
1981-01-01
The experimental verification of an inviscid, incompressible through-flow analysis method is presented. The primary component of this method is an axisymmetric streamline curvature technique which is used to compute the hub-to-tip flow field of a given turbomachine. To analyze the flow field in the blade-to-blade plane of the machine, the potential flow solution of an infinite cascade of airfoils is also computed using a source model technique. To verify the accuracy of such an analysis method an extensive experimental verification investigation was conducted using an axial flow research fan. Detailed surveys of the blade-free regions of the machine along with intra-blade surveys using rotating pressure sensing probes and blade surface static pressure taps provide a one-to-one relationship between measured and predicted data. The results of this investigation indicate the ability of this inviscid analysis method to predict the design flow field of the axial flow fan test rotor to within a few percent of the measured values.
В. М. Меженський
2015-06-01
Full Text Available Purpose. Reviewing a history of formation and current state of the national nomenclature and streamlining the Ukrainian scientific species names for the genus Fragaria L. Results. Controversial attitudes towards the use of names «sunytsi» (= garden strawberry and «polunytsi» (= hill strawberry are inherently present in the Ukrainian nomenclature of the genus Fragaria L. The Ukrainian scientific names of species of this group of plants should be brought into line with the generic name “Sunytsi” in plural. Nothogeneric name x Fragophora Mezhenskyj (= Dasiphora Rafin. x Fragaria L. is proposed. Conclusions. In a professional environment it is necessary to use only scientific names of species of the genus Fragaria – Sunytsi (= garden strawberry that is used in plural in Ukrainian. Concerning garden strawberry, in every day life and popular literature the usage of a derivative sunytsia (in Ukrainian in singular as well as polunytsia, polunytsi (in Ukrainian may be permissible.
NSTec Environmental Restoration
2011-08-31
This Streamlined Approach for Environmental Restoration (SAFER) Plan identifies the activities required for closure of Corrective Action Unit (CAU) 574, Neptune. CAU 574 is included in the Federal Facility Agreement and Consent Order (FFACO) (1996 [as amended March 2010]) and consists of the following two Corrective Action Sites (CASs) located in Area 12 of the Nevada National Security Site: (1) CAS 12-23-10, U12c.03 Crater (Neptune); (2) CAS 12-45-01, U12e.05 Crater (Blanca). This plan provides the methodology for the field activities that will be performed to gather the necessary information for closure of the two CASs. There is sufficient information and process knowledge regarding the expected nature and extent of potential contaminants to recommend closure of CAU 574 using the SAFER process. Based on historical documentation, personnel interviews, site process knowledge, site visits, photographs, field screening, analytical results, the results of the data quality objective (DQO) process (Section 3.0), and an evaluation of corrective action alternatives (Appendix B), closure in place with administrative controls is the expected closure strategy for CAU 574. Additional information will be obtained by conducting a field investigation to verify and support the expected closure strategy and provide a defensible recommendation that no further corrective action is necessary. This will be presented in a Closure Report that will be prepared and submitted to the Nevada Division of Environmental Protection (NDEP) for review and approval.
Porcel, Betina M; Denoeud, France; Opperdoes, Fred; Noel, Benjamin; Madoui, Mohammed-Amine; Hammarton, Tansy C; Field, Mark C; Da Silva, Corinne; Couloux, Arnaud; Poulain, Julie; Katinka, Michael; Jabbari, Kamel; Aury, Jean-Marc; Campbell, David A; Cintron, Roxana; Dickens, Nicholas J; Docampo, Roberto; Sturm, Nancy R; Koumandou, V Lila; Fabre, Sandrine; Flegontov, Pavel; Lukeš, Julius; Michaeli, Shulamit; Mottram, Jeremy C; Szöőr, Balázs; Zilberstein, Dan; Bringaud, Frédéric; Wincker, Patrick; Dollet, Michel
2014-02-01
Members of the family Trypanosomatidae infect many organisms, including animals, plants and humans. Plant-infecting trypanosomes are grouped under the single genus Phytomonas, failing to reflect the wide biological and pathological diversity of these protists. While some Phytomonas spp. multiply in the latex of plants, or in fruit or seeds without apparent pathogenicity, others colonize the phloem sap and afflict plants of substantial economic value, including the coffee tree, coconut and oil palms. Plant trypanosomes have not been studied extensively at the genome level, a major gap in understanding and controlling pathogenesis. We describe the genome sequences of two plant trypanosomatids, one pathogenic isolate from a Guianan coconut and one non-symptomatic isolate from Euphorbia collected in France. Although these parasites have extremely distinct pathogenic impacts, very few genes are unique to either, with the vast majority of genes shared by both isolates. Significantly, both Phytomonas spp. genomes consist essentially of single copy genes for the bulk of their metabolic enzymes, whereas other trypanosomatids e.g. Leishmania and Trypanosoma possess multiple paralogous genes or families. Indeed, comparison with other trypanosomatid genomes revealed a highly streamlined genome, encoding for a minimized metabolic system while conserving the major pathways, and with retention of a full complement of endomembrane organelles, but with no evidence for functional complexity. Identification of the metabolic genes of Phytomonas provides opportunities for establishing in vitro culturing of these fastidious parasites and new tools for the control of agricultural plant disease.
Betina M Porcel
2014-02-01
Full Text Available Members of the family Trypanosomatidae infect many organisms, including animals, plants and humans. Plant-infecting trypanosomes are grouped under the single genus Phytomonas, failing to reflect the wide biological and pathological diversity of these protists. While some Phytomonas spp. multiply in the latex of plants, or in fruit or seeds without apparent pathogenicity, others colonize the phloem sap and afflict plants of substantial economic value, including the coffee tree, coconut and oil palms. Plant trypanosomes have not been studied extensively at the genome level, a major gap in understanding and controlling pathogenesis. We describe the genome sequences of two plant trypanosomatids, one pathogenic isolate from a Guianan coconut and one non-symptomatic isolate from Euphorbia collected in France. Although these parasites have extremely distinct pathogenic impacts, very few genes are unique to either, with the vast majority of genes shared by both isolates. Significantly, both Phytomonas spp. genomes consist essentially of single copy genes for the bulk of their metabolic enzymes, whereas other trypanosomatids e.g. Leishmania and Trypanosoma possess multiple paralogous genes or families. Indeed, comparison with other trypanosomatid genomes revealed a highly streamlined genome, encoding for a minimized metabolic system while conserving the major pathways, and with retention of a full complement of endomembrane organelles, but with no evidence for functional complexity. Identification of the metabolic genes of Phytomonas provides opportunities for establishing in vitro culturing of these fastidious parasites and new tools for the control of agricultural plant disease.
Charge Exchange Induced X-ray Emission of Fe XXV and Fe XXVI via a Streamlined Model
Mullen, P D; Lyons, D; Stancil, P C
2016-01-01
Charge exchange is an important process for the modeling of X-ray spectra obtained by the Chandra, XMM-Newton, and Suzaku X-ray observatories, as well as the anticipated Astro-H mission. The understanding of the observed X-ray spectra produced by many astrophysical environments is hindered by the current incompleteness of available atomic and molecular data -- especially for charge exchange. Here, we implement a streamlined program set that applies quantum defect methods and the Landau-Zener theory to generate total, n-resolved, and nlS-resolved cross sections for any given projectile ion/ target charge exchange collision. Using this data in a cascade model for X-ray emission, theoretical spectra for such systems can be predicted. With these techniques, Fe25+ and Fe26+ charge exchange collisions with H, He, H2, N2, H2O, and CO are studied for single electron capture. These systems have been selected as they illustrate computational difficulties for high projectile charges. Further, Fe XXV and Fe XXVI emission...
Baldassari, Laura E; Salter, Amber R; Longbrake, Erin E; Cross, Anne H; Naismith, Robert T
2017-07-01
The Expanded Disability Status Scale (EDSS) is the standard measure of disability in multiple sclerosis clinical trials. The EDSS has limited application in the clinical setting due to required completion time and scoring complexity. Systematically recording an objective, simplified, less time-intensive, and neurologist-derived disability score would be beneficial for patient care. To develop and validate a streamlined version of the Expanded Disability Status Scale (sEDSS) for clinical monitoring. The EDSS was modified by eliminating maneuvers with no impact on function, consolidating redundancies, and simplifying scoring. This sEDSS was refined and preliminarily validated using a pilot cohort of 102 patients. Subsequently, the sEDSS was retrospectively validated using 968 patients from the CombiRx trial. We evaluated correlation and agreement between each functional system as well as the overall sEDSS and EDSS. The sEDSS correlated strongly with the EDSS, both overall (Spearman's rho = 0.93) and for each functional system (Spearman's rho 0.65-0.97). Correlation was slightly lower for functional systems where scoring was modified for consolidation and simplification. The sEDSS had strong agreement and correlation with the existing EDSS and can provide a useful measure of disability in clinical practice.
Gonzalez-Esquer, C Raul; Shubitowski, Tyler B; Kerfeld, Cheryl A
2015-09-01
Bacterial microcompartments (BMCs) are self-assembling organelles that sequester segments of biochemical pathways within a protein shell. Given their functional diversity, BMCs constitute a rich source of metabolic modules for applications in synthetic biology. The carboxysome, the cyanobacterial BMC for CO(2) fixation, has attracted significant attention as a target for installation into chloroplasts and serves as the foundation for introducing other types of BMCs into plants. Carboxysome assembly involves a series of protein-protein interactions among at least six gene products to form a metabolic core, around which the shell assembles. This complexity creates significant challenges for the transfer, regulation, and assembly of carboxysomes, or any of the myriad of functionally distinct BMCs, into heterologous systems. To overcome this bottleneck, we constructed a chimeric protein in the cyanobacterium Synechococcus elongatus that structurally and functionally replaces four gene products required for carboxysome formation. The protein was designed based on protein domain interactions in the carboxysome core. The resulting streamlined carboxysomes support photosynthesis. This strategy obviates the need to regulate multiple genes and decreases the genetic load required for carboxysome assembly in heterologous systems. More broadly, the reengineered carboxysomes represent a proof of concept for a domain fusion approach to building multifunctional enzymatic cores that should be generally applicable to the engineering of BMCs for new functions and cellular contexts.
Minh D. Pham
2016-05-01
Full Text Available While mass spectrometry (MS plays a key role in proteomics research, characterization of membrane proteins (MP by MS has been a challenging task because of the presence of a host of interfering chemicals in the hydrophobic protein extraction process, and the low protease digestion efficiency. We report a sample preparation protocol, two-phase separation with Triton X-100, induced by NaCl, with coomassie blue added for visualizing the detergent-rich phase, which streamlines MP preparation for SDS-PAGE analysis of intact MP and shot-gun proteomic analyses. MP solubilized in the detergent-rich milieu were then sequentially extracted and fractionated by surface-oxidized nanodiamond (ND at three pHs. The high MP affinity of ND enabled extensive washes for removal of salts, detergents, lipids, and other impurities to ensure uncompromised ensuing purposes, notably enhanced proteolytic digestion and down-stream mass spectrometric (MS analyses. Starting with a typical membranous cellular lysate fraction harvested with centrifugation/ultracentrifugation, MP purities of 70%, based on number (not weight of proteins identified by MS, was achieved; the weight-based purity can be expected to be much higher.
Peng, Zhengwei; Yang, Bo; Mattaparti, Sarathy; Shulok, Thom; Thacher, Thomas; Kong, James; Kostrowicki, Jaroslav; Hu, Qiyue; Na, James; Zhou, Joe Zhongxiang; Klatte, David; Chao, Bo; Ito, Shogo; Clark, John; Sciammetta, Nunzio; Coner, Bob; Waller, Chris; Kuki, Atsuo
2011-01-01
PGVL Hub is an integrated molecular design desktop tool that has been developed and globally deployed throughout Pfizer discovery research units to streamline the design and synthesis of combinatorial libraries and singleton compounds. This tool supports various workflows for design of singletons, combinatorial libraries, and Markush exemplification. It also leverages the proprietary PGVL virtual space (which contains 10(14) molecules spanned by experimentally derived synthesis protocols and suitable reactants) for lead idea generation, lead hopping, and library design. There had been an intense focus on ease of use, good performance and robustness, and synergy with existing desktop tools such as ISIS/Draw and SpotFire. In this chapter we describe the three-tier enterprise software architecture, key data structures that enable a wide variety of design scenarios and workflows, major technical challenges encountered and solved, and lessons learned during its development and deployment throughout its production cycles. In addition, PGVL Hub represents an extendable and enabling platform to support future innovations in library and singleton compound design while being a proven channel to deliver those innovations to medicinal chemists on a global scale.
Millar Andrew J
2009-02-01
Full Text Available Abstract Generating and identifying transformants is essential for many studies of gene function. In Arabidopsis thaliana, a revolutionary protocol termed floral dip is now the most widely used transformation method. Although robust, it involves a number of relatively time-consuming and laborious steps, including manipulating an Agrobacterium tumefaciens culture and aseptic procedures for the selection of plant lines harboring antibiotic-selection markers. Furthermore, where multiple transgenes are to be introduced, achieving this by sequential transformations over multiple generations adds significantly to the time required. To circumvent these bottlenecks, we have developed three streamlined sub-protocols. First, we find that A. thaliana can be transformed by dipping directly into an A. tumefaciens culture supplemented with surfactant, eliminating the need for media exchange to a buffered solution. Next, we illustrate that A. thaliana lines possessing a double-transformation event can be readily generated by simply by floral-dipping into a mixture of two A. tumefaciens cultures harboring distinct transformation vectors. Finally, we report an alternative method of transformant selection on chromatography sand that does not require surface sterilization of seeds. These sub-protocols, which can be used separately or in combination, save time and money, and reduce the possibility of contamination.
Yu, K.; Takahashi, K.; Nonoshita, T.; Ikeo, S. [Sophia Univ., Tokyo (Japan)
2000-05-15
The present paper describes the numerical analysis of the flow through a poppet valve by a streamline-coordinate system. Using this system, poppet valves with various shapes can easily be analysed, because a streamline along a solid wall or a free surface can be chosen as a coordinate. Parameters used in this analysis are poppet shape (cone angle for conical type and radius for spherical type), seat chamfer width, seat chamfer angle, valve lift and flow rate. Discharge coefficients and flow forces acting on poppets were analysed in detail, The computed results were in good agreement with the experimental ones. The conclusions are as follows: The flow forces on the poppet decrease with an increase in valve lift; The flow force on the conical poppet with a sharp edge seat is larger than that with a chamfered seat; The flow force is almost independent of flow rate for sharp edge seat, but strongly dependent for chamfered seat. (author)
NSTec Environmental Restoration
2008-09-01
The following is an addendum to the Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 134: Aboveground Storage Tanks, Nevada Test Site, Nevada, DOE/NV--1275, dated May 2008. This addendum expands upon information provided in the May 2008 plan. It provides specific details regarding samples to be collected at Corrective Action Sites 15-01-05 and 29-01-01. It also provides discussion and rationale for establishing the spatial boundaries of Corrective Action Sites.
NSTec Environmental Restoration
2009-03-31
This Streamlined Approach for Environmental Restoration Plan covers activities associated with Corrective Action Unit (CAU) 107 of the Federal Facility Agreement and Consent Order (1996 [as amended February 2008]). CAU 107 consists of the following Corrective Action Sites (CASs) located in Areas 1, 2, 3, 4, 5, 9, 10, and 18 of the Nevada Test Site. {sm_bullet} CAS 01-23-02, Atmospheric Test Site - High Alt{sm_bullet} CAS 02-23-02, Contaminated Areas (2){sm_bullet} CAS 02-23-03, Contaminated Berm{sm_bullet} CAS 02-23-10, Gourd-Amber Contamination Area{sm_bullet} CAS 02-23-11, Sappho Contamination Area{sm_bullet} CAS 02-23-12, Scuttle Contamination Area{sm_bullet} CAS 03-23-24, Seaweed B Contamination Area{sm_bullet} CAS 03-23-27, Adze Contamination Area{sm_bullet} CAS 03-23-28, Manzanas Contamination Area{sm_bullet} CAS 03-23-29, Truchas-Chamisal Contamination Area{sm_bullet} CAS 04-23-02, Atmospheric Test Site T4-a{sm_bullet} CAS 05-23-06, Atmospheric Test Site{sm_bullet} CAS 09-23-06, Mound of Contaminated Soil{sm_bullet} CAS 10-23-04, Atmospheric Test Site M-10{sm_bullet} CAS 18-23-02, U-18d Crater (Sulky) Based on historical documentation, personnel interviews, site process knowledge, site visits, photographs, engineering drawings, field screening, analytical results, and the results of data quality objectives process (Section 3.0), closure in place with administrative controls or no further action will be implemented for CAU 107.
NSTec Environmental Restoration
2008-09-30
This Streamlined Approach for Environmental Restoration Plan covers activities associated with Corrective Action Unit (CAU) 107 of the Federal Facility Agreement and Consent Order (FFACO, 1996 [as amended February 2008]). CAU 107 consists of the following Corrective Action Sites (CASs) located in Areas 1, 2, 3, 4, 5, 9, 10, and 18 of the Nevada Test Site. (1) CAS 01-23-02, Atmospheric Test Site - High Alt; (2) CAS 02-23-02, Contaminated Areas (2); (3) CAS 02-23-03, Contaminated Berm; (4) CAS 02-23-10, Gourd-Amber Contamination Area; (5) CAS 02-23-11, Sappho Contamination Area; (6) CAS 02-23-12, Scuttle Contamination Area; (7) CAS 03-23-24, Seaweed B Contamination Area; (8) CAS 03-23-27, Adze Contamination Area; (9) CAS 03-23-28, Manzanas Contamination Area; (10) CAS 03-23-29, Truchas-Chamisal Contamination Area; (11) CAS 04-23-02, Atmospheric Test Site T4-a; (12) CAS 05-23-06, Atmospheric Test Site; (13) CAS 09-23-06, Mound of Contaminated Soil; (14) CAS 10-23-04, Atmospheric Test Site M-10; and (15) CAS 18-23-02, U-18d Crater (Sulky). Based on historical documentation, personnel interviews, site process knowledge, site visits, photographs, engineering drawings, field screening, analytical results, and the results of data quality objectives process (Section 3.0), closure in place with administrative controls or no further action will be implemented for CAU 107. CAU 107 closure activities will consist of verifying that the current postings required under Title 10 Code of Federal Regulations (CFR) Part 835 are in place and implementing use restrictions (URs) at two sites, CAS 03-23-29 and CAS 18-23-02. The current radiological postings combined with the URs are adequate administrative controls to limit site access and worker dose.
Charge Exchange-induced X-Ray Emission of Fe xxv and Fe xxvI via a Streamlined Model
Mullen, P. D.; Cumbee, R. S.; Lyons, D.; Stancil, P. C.
2016-06-01
Charge exchange (CX) is an important process for the modeling of X-ray spectra obtained by the Chandra, XMM-Newton, and Suzaku X-ray observatories, as well as the anticipated Astro-H mission. The understanding of the observed X-ray spectra produced by many astrophysical environments is hindered by the current incompleteness of available atomic and molecular data—especially for CX. Here, we implement a streamlined program set that applies quantum defect methods and the Landau-Zener theory to generate total, n-resolved, and n{\\ell }S-resolved cross sections for any given projectile ion/target CX collision. By using these data in a cascade model for X-ray emission, theoretical spectra for such systems can be predicted. With these techniques, Fe25+ and Fe26+ CX collisions with H, He, H2, N2, H2O, and CO are studied for single-electron capture (SEC). These systems have been selected because they illustrate computational difficulties for high projectile charges. Furthermore, Fe xxv and Fe xxvi emission lines have been detected in the Galactic center and Galactic ridge. Theoretical X-ray spectra for these collision systems are compared to experimental data generated by an electron-beam ion trap study. Several ℓ-distribution models have been tested for Fe25+ and Fe26+ SEC. Such analyses suggests that commonly used ℓ-distribution models struggle to accurately reflect the true distribution of electron capture as understood by more advanced theoretical methods.
Martin Wu
2004-03-01
Full Text Available The complete sequence of the 1,267,782 bp genome of Wolbachia pipientis wMel, an obligate intracellular bacteria of Drosophila melanogaster, has been determined. Wolbachia, which are found in a variety of invertebrate species, are of great interest due to their diverse interactions with different hosts, which range from many forms of reproductive parasitism to mutualistic symbioses. Analysis of the wMel genome, in particular phylogenomic comparisons with other intracellular bacteria, has revealed many insights into the biology and evolution of wMel and Wolbachia in general. For example, the wMel genome is unique among sequenced obligate intracellular species in both being highly streamlined and containing very high levels of repetitive DNA and mobile DNA elements. This observation, coupled with multiple evolutionary reconstructions, suggests that natural selection is somewhat inefficient in wMel, most likely owing to the occurrence of repeated population bottlenecks. Genome analysis predicts many metabolic differences with the closely related Rickettsia species, including the presence of intact glycolysis and purine synthesis, which may compensate for an inability to obtain ATP directly from its host, as Rickettsia can. Other discoveries include the apparent inability of wMel to synthesize lipopolysaccharide and the presence of the most genes encoding proteins with ankyrin repeat domains of any prokaryotic genome yet sequenced. Despite the ability of wMel to infect the germline of its host, we find no evidence for either recent lateral gene transfer between wMel and D. melanogaster or older transfers between Wolbachia and any host. Evolutionary analysis further supports the hypothesis that mitochondria share a common ancestor with the alpha-Proteobacteria, but shows little support for the grouping of mitochondria with species in the order Rickettsiales. With the availability of the complete genomes of both species and excellent genetic tools for
Mehmani, Yashar; Oostrom, Mart; Balhoff, Matthew T.
2014-03-01
Several approaches have been developed in the literature for solving flow and transport at the pore scale. Some authors use a direct modeling approach where the fundamental flow and transport equations are solved on the actual pore-space geometry. Such direct modeling, while very accurate, comes at a great computational cost. Network models are computationally more efficient because the pore-space morphology is approximated. Typically, a mixed cell method (MCM) is employed for solving the flow and transport system which assumes pore-level perfect mixing. This assumption is invalid at moderate to high Peclet regimes. In this work, a novel Eulerian perspective on modeling flow and transport at the pore scale is developed. The new streamline splitting method (SSM) allows for circumventing the pore-level perfect-mixing assumption, while maintaining the computational efficiency of pore-network models. SSM was verified with direct simulations and validated against micromodel experiments; excellent matches were obtained across a wide range of pore-structure and fluid-flow parameters. The increase in the computational cost from MCM to SSM is shown to be minimal, while the accuracy of SSM is much higher than that of MCM and comparable to direct modeling approaches. Therefore, SSM can be regarded as an appropriate balance between incorporating detailed physics and controlling computational cost. The truly predictive capability of the model allows for the study of pore-level interactions of fluid flow and transport in different porous materials. In this paper, we apply SSM and MCM to study the effects of pore-level mixing on transverse dispersion in 3-D disordered granular media.
MIXED COVOLUME-UPWIND FINITE VOLUME METHODS FOR SEMICONDUCTOR DEVICE%半导体瞬态问题的混合迎风有限体积格式
杨青
2011-01-01
The mathematical model of the semiconductor device is described by the initial boundary value problem for a system of three quasilinear partial differential equations. The electrostatic potential equation is approximated with the aid of mixed covolume method, while the electron and hole concentrations equations are approximated with upwind finite volume methods. The optimal error estimates are obtained. Finally, three numerical examples are given.%半导体器件的瞬时状态由包含3个拟线性偏微分方程所组成的方程组的初边值问题来描述.在三角剖分的基础上,对椭圆型的电子位势方程采用混合有限体积元法来逼近,对对流扩散型的电子浓度和空穴浓度方程采用迎风有限体积元方法来逼近,并进行了详细的理论分析,得到了最优阶的误差估计结果.最后,针对混合有限体积元法和迎风有限体积元法分别单独使用以及两种方法结合使用的情形给出了不同的数值算例.
多孔介质两相流的守恒迎风有限元法%CONSERVATIVE UPWIND FINITE ELEMENT METHOD FOR TWO-PHASE FLOW IN POROUS MEDIA
马纳·萨德; 胡健伟
2001-01-01
Two-phase, immiscible in compressible flow in porous media governed by a system of non-linear partial differential equations arised from reservoir simulation is discussed. Galerkin method is applied for the pressure equation. For the convection-dominated saturation equation, a kind of partial upwind finite element scheme is constructed. The numerical solution got by this scheme satisfies the discrete mass conservation law and converges to the solution in norm L∞(0,T;L2(Ω)).%本文讨论油藏模拟中描述多孔介质两相不可压非混溶流动的偏微分方程组.压力方程用Galerkin方法,而对流占优的饱和度方程用一类部分迎风有限元法.数值解满足离散的质量守恒原理,并以L∞(0,Y;L2(Ω))范收敛于原解.
Arianespace streamlines launch procedures
Lenorovitch, Jeffrey M.
1992-06-01
Ariane has entered a new operational phase in which launch procedures have been enhanced to reduce the length of launch campaigns, lower mission costs, and increase operational availability/flexibility of the three-stage vehicle. The V50 mission utilized the first vehicle from a 50-launcher production lot ordered by Arianespace, and was the initial flight with a stretched third stage that enhances Ariane's performance. New operational procedures were introduced gradually over more than a year, starting with the V42 launch in January 1991.
Thompson, Andrew G H; France, Emma F
2010-05-13
Obtaining the necessary approvals and permission for clinical research requires successful negotiation of the ethical and R&D layers of the NHS. Differences in structure and governance frameworks feature between the constituent nations of the UK (England, Scotland, Wales and Northern Ireland), which adds complexity to cross-national studies. Difficulties in carrying out research in the NHS in the UK due to bureaucratic and time-consuming governance processes have led to the development of a new system of application and co-ordination from 2009. This paper illustrates how this new system fails to be consistent and streamlined and is unlikely to become so unless changes are made to the implementation and management of the governance processes. We present a case study of the research governance process at the survey stage of an investigation into the use, preferences and need for information by people making choices or decisions about health care. The method involved home-based, face-to-face interviewing in a questionnaire survey in relation to decisions about lymphoma treatment, Down's syndrome screening in pregnancy, and caring for people with dementia. Our experience of the ethics stage was very positive, noting an efficient process of application and a speedy decision, both in relation to the initial application and to subsequent substantial amendments. By contrast, the R&D stages were very slow, most with unexplained delays, but some offering contradictory advice and exhibiting a lack of clear guidance and training for NHS staff. The R&D arrangements in Scotland were far quicker and more likely to be successful than in England. Overall, the delays were so severe that substantial parts of the research could not be delivered as planned within the funding timescale. If high-quality research in the NHS, particularly in England, is to be delivered in a timely and cost-effective way, R&D processes for gaining research governance approval need improvement. Attention is
K. B. Campbell
2001-11-01
This Streamlined Approach for Environmental Restoration (SAFER) plan addresses the activities necessary to close Corrective Action Unit (CAU) 398: Area 25 Spill Sites. CAU 398, located in Area 25 of the Nevada Test Site, is currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO) (FFACO, 1996), and consists of the following 13 Corrective Action Sites (CASs) (Figure 1): (1) CAS 25-44-01 , a fuel spill on soil that covers a concrete pad. The origins and use of the spill material are unknown, but the spill is suspected to be railroad bedding material. (2) CAS 25-44-02, a spill of liquid to the soil from leaking drums. (3) CAS 25-44-03, a spill of oil from two leaking drums onto a concrete pad and surrounding soil. (4) CAS 25-44-04, a spill from two tanks containing sulfuric acid and sodium hydroxide used for a water demineralization process. (5) CAS 25-25-02, a fuel or oil spill from leaking drums that were removed in 1992. (6) CAS 25-25-03, an oil spill adjacent to a tipped-over drum. The source of the drum is not listed, although it is noted that the drum was removed in 1991. (7) CAS 25-25-04, an area on the north side of the Engine-Maintenance, Assembly, and Disassembly (E-MAD) facility, where oils and cooling fluids from metal machining operations were poured directly onto the ground. (8) CAS 25-25-05, an area of oil and/or hydraulic fluid spills beneath the heavy equipment once stored there. (9) CAS 25-25-06, an area of diesel fuel staining beneath two generators that have since been removed. (10) CAS 25-25-07, an area of hydraulic oil spills associated with a tunnel-boring machine abandoned inside X-Tunnel. (11) CAS 25-25-08, an area of hydraulic fluid spills associated with a tunnel-boring machine abandoned inside Y-Tunnel. (12) CAS 25-25-16, a diesel fuel spill from an above-ground storage tank located near Building 3320 at Engine Test Stand-1 (ETS-1) that was removed in 1998. (13) CAS 25-25-17, a hydraulic oil spill
Mark Krauss
2010-06-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 114, Area 25 EMAD Facility, identified in the Federal Facility Agreement and Consent Order (FFACO). Corrective Action Unit 114 comprises the following corrective action site (CAS) located in Area 25 of the Nevada Test Site: • 25-41-03, EMAD Facility This plan provides the methodology for field activities needed to gather the necessary information for closing CAS 25-41-03. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 114 using the SAFER process. Additional information will be obtained by conducting a field investigation before selecting the appropriate corrective action for CAS 25-41-03. It is anticipated that the results of the field investigation and implementation of corrective actions will support a defensible recommendation that no further corrective action is necessary. If it is determined that complete clean closure cannot be accomplished during the SAFER, then a hold point will have been reached and the Nevada Division of Environmental Protection (NDEP) will be consulted to determine whether the remaining contamination will be closed under the alternative corrective action of closure in place. This will be presented in a closure report that will be prepared and submitted to NDEP for review and approval. The CAS will be investigated based on the data quality objectives (DQOs) developed on April 30, 2009, by representatives of NDEP and the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office. The DQO process was used to identify and define the type, amount, and quality of data needed to determine and implement appropriate corrective actions for CAS 25-41-03. The following text summarizes the SAFER
UPWIND SCHEME FOR IDEAL 2-D MHD FLOWS BASED ON UNSTRUCTURED MESH%非结构网格二维理想MHD绕流逆风格式解法
潘勇; 王江峰; 伍贻兆
2007-01-01
An upwind scheme based on the unstructured mesh is developed to solve ideal 2-D magnetohydrodynamics(MHD) equations. The inviscid fluxes are approximated by using the modified advection upstream splitting method(AUSM) scheme, and a 5-stage explicit Runge-Kutta scheme is adopted in the time integration. To avoid the influence of the magnetic field divergence created during the simulation, the hyperbolic divergence cleaning method is introduced. The shock-capturing properties of the method are verified by solving the MHD shock-tube problem. Then the 2-D nozzle flow with the magnetic field is numerically simulated on the unstructured mesh. Computational results demonstrate the effects of the magnetic field and agree well with those from references.%在非结构网格上发展了针对二维理想磁流体方程组的逆风格式求解方法.控制方程中的对流项采用AUSM格式处理,时间推进采用显式5步龙格-库塔方法.为了消除计算中产生的磁场散度的影响,引入了双曲型散度清除方法.通过对磁流体激波管问题的求解验证了该方法对激波的捕捉能力,对有均匀磁场干扰下的喷管流动情况进行了数值模拟,并与文献中结果进行了对比.计算结果显示了磁场对磁流体流动的干扰效应,该结果与参考文献中的数值模拟结果相吻合.
孔龙星; 汤晓安; 李欢
2014-01-01
The streamline method is an important method in the visualization of 3D vector fields.A view-dependent streamline simplification method for 3D vector fields based on feature-preservation was proposed to solve the problems of streamline occlusion and visual confusion caused by excessive streamlines,and to ensure the streamlines could present the variation law and important features of vector fields exactly.A streamline set of 3D vector fields was generated by particle tracking and was mapped between view-dependents.A feature-preservation computation of the streamline set was implemented.The streamline set is effectively simplified by computing visual effect metric based on iteration.Experimental results show that the visual effects of the streamlines are enhanced on the basis of valid feature-preservation of vector fields.%为了解决三维矢量场可视化中流线数量过多造成的遮挡与视觉混乱问题，同时保证流线能够准确描述矢量场变化规律与重要特征，提出了一种基于特征保持的视点相关三维矢量场流线简化方法。采用粒子跟踪生成3D矢量场流线集，并进行视点相关映射；对流线集进行特征保持计算；基于流线视觉效果度量对流线集进行迭代简化计算，从而实现流线集的有效简化。实验结果表明，能够有效保持矢量场的物理特征，且具有较好的流线视觉效果。
NSTec Environmental Restoration
2008-05-31
This Streamlined Approach for Environmental Restoration (SAFER) Plan identifies the activities required for the closure of Corrective Action Unit (CAU) 134, Aboveground Storage Tanks. CAU 134 is currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO) (FFACO, 1996; as amended February 2008) and consists of four Corrective Action Sites (CASs) located in Areas 3, 15, and 29 of the Nevada Test Site (NTS) (Figure 1): (1) CAS 03-01-03, Aboveground Storage Tank; (2) CAS 03-01-04, Tank; (3) CAS 15-01-05, Aboveground Storage Tank; and (4) CAS 29-01-01, Hydrocarbon Stain. CAS 03-01-03 consists of a mud tank that is located at the intersection of the 3-07 and the 3-12 Roads in Area 3 of the NTS. The tank and its contents are uncontaminated and will be dispositioned in accordance with applicable federal, state, and local regulations. This CAS will be closed by taking no further action. CAS 03-01-04 consists of a potable water tank that is located at the Core Complex in Area 3 of the NTS. The tank will be closed by taking no further action. CAS 15-01-05 consists of an aboveground storage tank (AST) and associated impacted soil, if any. This CAS is located on a steep slope near the Climax Mine in Area 15 of the NTS. The AST is empty and will be dispositioned in accordance with applicable federal, state, and local regulations. Soil below the AST will be sampled to identify whether it has been impacted by chemicals at concentrations exceeding the action levels. It appears that the tank is not at its original location. Soil will also be sampled at the original tank location, if it can be found. If soil at either location has been impacted at concentrations that exceed the action levels, then the extent of contamination will be identified and a use restriction (UR) will be implemented. The site may be clean closed if contamination is less than one cubic yard in extent and can be readily excavated. If action levels are not exceeded, then no
Mark Krauss
2010-06-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 566, EMAD Compound, identified in the Federal Facility Agreement and Consent Order (FFACO). Corrective Action Unit 566 comprises the following corrective action site (CAS) located in Area 25 of the Nevada Test Site: • 25-99-20, EMAD Compound This plan provides the methodology for field activities needed to gather the necessary information for closing CAS 25-99-20. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 566 using the SAFER process. Additional information will be obtained by conducting a field investigation before selecting the appropriate corrective action. It is anticipated that the results of the field investigation and implementation of a corrective action of clean closure will support a defensible recommendation that no further corrective action is necessary. If it is determined that complete clean closure cannot be accomplished during the SAFER, then a hold point will have been reached and the Nevada Division of Environmental Protection (NDEP) will be consulted to determine whether the remaining contamination will be closed under the alternative corrective action of closure in place. This will be presented in a closure report that will be prepared and submitted to NDEP for review and approval. The data quality objective (DQO) strategy for CAU 566 was developed at a meeting on April 30, 2009, by representatives of NDEP and the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office. The DQO process was used to identify and define the type, amount, and quality of data needed to determine and implement appropriate corrective actions for CAU 566. The following text summarizes the SAFER activities that will
王晓东; 欧阳洁; 王玉龙; 蒋涛
2012-01-01
A stable and efficient element-free Galerkin method is proposed for steady convection-diffusion problems. In the method integrations are computed with a local Taylor expansion nodal integral technique. According to convection-dominated degree, integration nodes are adaptively shifted opposite to the streamline direction. Compared with conventional element-free Galerkin method with stabilization, the method exhibits better stability and higher efficiency in solving convection-dominated convection-diffusion problems. It is a pure meshfree method, which is independent of background integral. Moreover, the method is easy to be implemented.%建立求解稳态对流-扩散方程的一种稳定、高效的无单元Galerkin方法.该方法计算积分时采用基于局部Taylor展开的节点积分,并根据对流占优的程度对积分节点进行自适应迎风偏移.与传统的使用稳定化的无单元Galerkin方法相比,该方法是一种不依赖于背景网格积分的纯无网格方法,具有更好的稳定性和较高的计算效率, 其程序实施更为简便.
王江峰; 伍贻兆
2007-01-01
A parallelized upwind flux splitting scheme for supersonic reacting flows on hybrid meshes is presented. The complexity of super/hyper-sonic combustion flows makes it necessary to establish solvers with higher resolution and efficiency for multi-component Euler/N-S equations. Hence, a spatial second-order van Leer type flux vector splitting scheme is established by introducing auxiliary points in interpolation, and a domain decomposition method used on unstructured hybrid meshes for obtaining high calculating efficiency. The numerical scheme with five-stage Runge-Kutta time step method is implemented to the simulation of combustion flows, including the supersonic hydrogen/air combustion and the normal injection of hydrogen into reacting flows. Satisfying results are obtained compared with limited references.%基于有限体积迎风格式对超声速燃烧流场进行了的数值模拟.由于超声速燃烧流场绕流的复杂性,要求对多组分Euler/N-S方程求解的数值模拟方法应具有较高的计算精度及效率.本文引用辅助点方法建立了具有空间二阶精度的van Leer迎风矢通量分裂格式,并应用于超声速燃烧流场绕流的数值模拟.化学反应为氢气/空气十反应模型,采用考虑了化学反应特征时间的当地时间步长显式Runge-Kutta时间推进格式.对钝头体模型爆轰现象、后向台阶氢气喷射及二维内外流超声速燃烧流场模型进行了区域分裂技术的并行计算.计算结果与参考文献作了对比,得到了满意的结果.
Pereira, Luis Carlos Martins
1998-06-15
New Petrov-Galerkin formulations on the finite element methods for convection-diffusion problems with boundary layers are presented. Such formulations are based on a consistent new theory on discontinuous finite element methods. Existence and uniqueness of solutions for these problems in the new finite element spaces are demonstrated. Some numerical experiments shows how the new formulation operate and also their efficacy. (author)
J. L. Smith
2001-01-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the action necessary for the closure in place of Corrective Action Unit (CAU) 113 Area 25 Reactor Maintenance, Assembly, and Disassembly Facility (R-MAD). CAU 113 is currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO) (NDEP, 1996). The CAU is located in Area 25 of the Nevada Test Site (NTS) and consists of Corrective Action Site (CAS) 25-04-01, R-MAD Facility (Figures 1-2). This plan provides the methodology for closure in place of CAU 113. The site contains radiologically impacted and hazardous material. Based on preassessment field work, there is sufficient process knowledge to close in place CAU 113 using the SAFER process. At a future date when funding becomes available, the R-MAD Building (25-3110) will be demolished and inaccessible radiologic waste will be properly disposed in the Area 3 Radiological Waste Management Site (RWMS).
Alfred Wickline
2007-04-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses closure for Corrective Action Unit (CAU) 124, Areas 8, 15, and 16 Storage Tanks, identified in the Federal Facility Agreement and Consent Order. Corrective Action Unit 124 consists of five Corrective Action Sites (CASs) located in Areas 8, 15, and 16 of the Nevada Test Site as follows: • 08-02-01, Underground Storage Tank • 15-02-01, Irrigation Piping • 16-02-03, Underground Storage Tank • 16-02-04, Fuel Oil Piping • 16-99-04, Fuel Line (Buried) and UST This plan provides the methodology of field activities necessary to gather information to close each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 124 using the SAFER process.
NONE
1996-09-01
This plan addresses actions necessary for the restoration and closure of Corrective Action Unit (CAU) No. 430, Buried Depleted Uranium (DU) Artillery Round No. 1 (Corrective Action Site No. TA-55-003-0960), a buried and unexploded W-79 Joint Test Assembly (JTA) artillery test projectile with high explosives (HE), at the U.S. Department of Energy, Nevada Operations Office (DOE/NV) Tonopah Test Range (TTR) in south-central Nevada. It describes activities that will occur at the site as well as the steps that will be taken to gather adequate data to obtain a notice of completion from Nevada Division of Environmental Protection (NDEP). This plan was prepared under the Streamlined Approach for Environmental Restoration (SAFER) concept, and it will be implemented in accordance with the Federal Facility Agreement and Consent Order (FFACO) and the Resource Conservation and Recovery Act (RCRA) Industrial Sites Quality Assurance Project Plan.
Thornquist, Mark D; Edelstein, Cim; Goodman, Gary E; Omenn, Gilbert S
2002-02-01
With their extensive data and specimen repositories, clinical trials are a long-term, valuable resource to health researchers. However, assuring protection of participants' rights can be challenging, particularly when such trials are conducted at multiple sites with multiple Institutional Review Boards (IRBs). One little-used mechanism that can streamline IRB review in multisite trials while maintaining participants' protections is the single-study IRB Cooperative Agreement. This agreement is entirely different from reciprocity agreements between institutions. Beginning in 1996, the Beta-Carotene and Retinol Efficacy Trial established single-study IRB Cooperative Agreements among its performance sites, which reduced the average time to complete IRB approval from over 6 months to 1 month for each of many substudies. We describe our experience and make recommendations for other multisite clinical trials.
Jonas, Wayne B; Crawford, Cindy; Hilton, Lara; Elfenbaum, Pamela
2017-01-01
Answering the question of "what works" in healthcare can be complex and requires the careful design and sequential application of systematic methodologies. Over the last decade, the Samueli Institute has, along with multiple partners, developed a streamlined, systematic, phased approach to this process called the Scientific Evaluation and Review of Claims in Health Care (SEaRCH™). The SEaRCH process provides an approach for rigorously, efficiently, and transparently making evidence-based decisions about healthcare claims in research and practice with minimal bias. SEaRCH uses three methods combined in a coordinated fashion to help determine what works in healthcare. The first, the Claims Assessment Profile (CAP), seeks to clarify the healthcare claim and question, and its ability to be evaluated in the context of its delivery. The second method, the Rapid Evidence Assessment of the Literature (REAL(©)), is a streamlined, systematic review process conducted to determine the quantity, quality, and strength of evidence and risk/benefit for the treatment. The third method involves the structured use of expert panels (EPs). There are several types of EPs, depending on the purpose and need. Together, these three methods-CAP, REAL, and EP-can be integrated into a strategic approach to help answer the question "what works in healthcare?" and what it means in a comprehensive way. SEaRCH is a systematic, rigorous approach for evaluating healthcare claims of therapies, practices, programs, or products in an efficient and stepwise fashion. It provides an iterative, protocol-driven process that is customized to the intervention, consumer, and context. Multiple communities, including those involved in health service and policy, can benefit from this organized framework, assuring that evidence-based principles determine which healthcare practices with the greatest promise are used for improving the public's health and wellness.
罗万静; 王军磊; 王晓冬; 周英芳
2013-01-01
The mechanism of the fluid flow in low permeability reservoirs is different from that in middle-high permeability rese-rvoirs because of the existence of the Threshold Pressure Gradient (TPG). When the pressure gradient at some location is greater than the TPG, the fluid in porous media begins to flow. By applying the mirror image method and the principle of potential superposition, the steady-state pressure distribution and the stream function for infinite five-spot well patterns can be obtained for a low permea-bility reservoir with the TPG effect. Based on the streamlines distribution, the flowing and stagnant zones in five-spot well patterns can be clearly seen. By the definition of the effective startup coefficient (SUC), the ratio of the flowing and stagnant zones can be calculated accurately. It is shown that the SUC for five-spot well patterns is not constant, but decreases with the increase of the di-mensionless TPG. By increasing the effective permeability of the formation (such as by the acid treatment and the hydraulic fracture), in increasing the injection-production differential pressure or shortening the well space (such as by infilling well), the SUC can be improved. The results of the sensitivity analysis show that a better choice for the SUC enhancement is to shorten the well spacing for small permeability reservoirs and to increase the pressure difference for large permeability reservoirs. This streamline approach can be used to determine the distribution of remaining oil and provide guidance for infilling well.
Greene, Leasa A.; Isaac, Issa; Gray, Dean E.; Schwartz, Sarah A.
2007-01-01
Several species in the genus Echinacea are beneficial herbs popularly used for many ailments. The most popular Echinacea species for cultivation, wild collection, and herbal products include E. purpurea (L.) Moench, E. pallida (Nutt.) Nutt., and E. angustifolia (DC). Product adulteration is a key concern for the natural products industry, where botanical misidentification and introduction of other botanical and nonbotanical contaminants exist throughout the formulation and production process. Therefore, rapid and cost-effective methods that can be used to monitor these materials for complex product purity and consistency are of benefit to consumers and producers. The objective of this continuing research was to develop automated, high-throughput processing methods that, teamed with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis, differentiate Echinacea species by their mass profiles. Small molecules, peptide, and proteins from aerial parts (leaf/stem/flowers), seeds, and roots from E. purpurea and E. angustifolia; seeds and roots from E. pallida; and off-the-shelf Echinacea supplements were extracted and analyzed by MS using methods developed on the ProPrep liquid handling system (Genomic Solutions). Analysis of these samples highlighted key MS signal patterns from both small molecules and proteins that characterized the individual Echinacea materials analyzed. Based on analysis of pure Echinacea samples, off-the-shelf products containing Echinacea could then be evaluated in a streamlined process. Corresponding analysis of dietary supplements was used to monitor for product composition, including Echinacea species and plant materials used. These results highlight the potential for streamlined, automated approaches for agricultural species differentiation and botanical product evaluation. PMID:17916796
Gifford, Scott M; Becker, Jamie W; Sosa, Oscar A; Repeta, Daniel J; DeLong, Edward F
2016-11-22
The members of the OM43 clade of Betaproteobacteria are abundant coastal methylotrophs with a range of carbon-utilizing capabilities. However, their underlying transcriptional and metabolic responses to shifting conditions or different carbon substrates remain poorly understood. We examined the transcriptional dynamics of OM43 isolate NB0046 subjected to various inorganic nutrient, vitamin, and carbon substrate regimes over different growth phases to (i) develop a quantitative model of its mRNA content; (ii) identify transcriptional markers of physiological activity, nutritional state, and carbon and energy utilization; and (iii) identify pathways involved in methanol or naturally occurring dissolved organic matter (DOM) metabolism. Quantitative transcriptomics, achieved through addition of internal RNA standards, allowed for analyses on a transcripts-per-cell scale. This streamlined bacterium exhibited substantial shifts in total mRNA content (ranging from 1,800 to 17 transcripts cell(-1) in the exponential and deep stationary phases, respectively) and gene-specific transcript abundances (>1,000-fold increases in some cases), depending on the growth phase and nutrient conditions. Carbon metabolism genes exhibited substantial dynamics, including those for ribulose monophosphate, tricarboxylic acid (TCA), and proteorhodopsin, as well as methanol dehydrogenase (xoxF), which, while always the most abundant transcript, increased from 5 to 120 transcripts cell(-1) when cultures were nutrient and vitamin amended. In the DOM treatment, upregulation of TCA cycle, methylcitrate cycle, vitamin, and organic phosphorus genes suggested a metabolic route for this complex mixture of carbon substrates. The genome-wide inventory of transcript abundances produced here provides insight into a streamlined marine bacterium's regulation of carbon metabolism and energy flow, providing benchmarks for evaluating the activity of OM43 populations in situ IMPORTANCE: Bacteria exert a
P. V. Ramakrishna
2009-01-01
Full Text Available This article presents the study of Tip Chordline Sweeping (TCS and Axial Sweeping (AXS of low-speed axial compressor rotor blades against the performance of baseline unswept rotor (UNS for different tip clearance levels. The first part of the paper discusses the changes in design parameters when the blades are swept, while the second part throws light on the effect of sweep on tip leakage flow-related phenomena. 15 domains are studied with 5 sweep configurations (0∘, 20∘ TCS, 30∘ TCS, 20∘ AXS, and 30∘ AXS and for 3 tip clearances (0.0%, 0.7%, and 2.7% of the blade chord. A commercial CFD package is employed for the flow simulations and analysis. Results are well validated with experimental data. Forward sweep reduced the flow incidences. This is true all over the span with axial sweeping while little higher incidences below the mid span are observed with tip chordline sweeping. Sweeping is observed to lessen the flow turning. AXS rotors demonstrated more efficient energy transfer among the rotors. Tip chordline sweep deflected the flow towards the hub while effective positive dihedral induced with axial sweeping resulted in outward deflection of flow streamlines. These deflections are more at lower mass flow rates.
Brad Thomas Townsley
2015-05-01
Full Text Available Next Generation Sequencing (NGS is driving rapid advancement in biological understanding and RNA-sequencing (RNA-seq has become an indispensable tool for biology and medicine. There is a growing need for access to these technologies although preparation of NGS libraries remains a bottleneck to wider adoption. Here we report a novel method for the production of strand specific RNA-seq libraries utilizing inherent properties of double-stranded cDNA to capture and incorporate a sequencing adapter. Breath Adapter Directional sequencing (BrAD-seq reduces sample handling and requires far fewer enzymatic steps than most available methods to produce high quality strand-specific RNA-seq libraries. The method we present is optimized for 3-prime Digital Gene Expression (DGE libraries and can easily extend to full transcript coverage shotgun (SHO type strand-specific libraries and is modularized to accommodate a diversity of RNA and DNA input materials. BrAD-seq offers a highly streamlined and inexpensive option for RNA-seq libraries.
MacLeod, Daniel T; Antony, Jeyaraj; Martin, Aaron J; Moser, Rachel J; Hekele, Armin; Wetzel, Keith J; Brown, Audrey E; Triggiano, Melissa A; Hux, Jo Ann; Pham, Christina D; Bartsevich, Victor V; Turner, Caitlin A; Lape, Janel; Kirkland, Samantha; Beard, Clayton W; Smith, Jeff; Hirsch, Matthew L; Nicholson, Michael G; Jantz, Derek; McCreedy, Bruce
2017-04-05
Adoptive cellular therapy using chimeric antigen receptor (CAR) T cell therapies have produced significant objective responses in patients with CD19(+) hematological malignancies, including durable complete responses. Although the majority of clinical trials to date have used autologous patient cells as the starting material to generate CAR T cells, this strategy poses significant manufacturing challenges and, for some patients, may not be feasible because of their advanced disease state or difficulty with manufacturing suitable numbers of CAR T cells. Alternatively, T cells from a healthy donor can be used to produce an allogeneic CAR T therapy, provided the cells are rendered incapable of eliciting graft versus host disease (GvHD). One approach to the production of these cells is gene editing to eliminate expression of the endogenous T cell receptor (TCR). Here we report a streamlined strategy for generating allogeneic CAR T cells by targeting the insertion of a CAR transgene directly into the native TCR locus using an engineered homing endonuclease and an AAV donor template. We demonstrate that anti-CD19 CAR T cells produced in this manner do not express the endogenous TCR, exhibit potent effector functions in vitro, and mediate clearance of CD19(+) tumors in an in vivo mouse model. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.
Matthews, Patrick
2014-12-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 575, Area 15 Miscellaneous Sites, identified in the Federal Facility Agreement and Consent Order (FFACO). CAU 575 comprises the following four corrective action sites (CASs) located in Area 15 of the Nevada National Security Site: • 15-19-02, Waste Burial Pit • 15-30-01, Surface Features at Borehole Sites • 15-64-01, Decontamination Area • 15-99-03, Aggregate Plant This plan provides the methodology for field activities needed to gather the necessary information for closing each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 575 using the SAFER process. Additional information will be obtained by conducting a field investigation to document and verify the adequacy of existing information, to affirm the predicted corrective action decisions, and to provide sufficient data to implement the corrective actions. This will be presented in a closure report that will be prepared and submitted to the Nevada Division of Environmental Protection (NDEP) for review and approval.
Matthews, Patrick; Burmeister, Mark
2014-04-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 415, Project 57 No. 1 Plutonium Dispersion (NTTR). CAU 415 is located on Range 4808A of the Nevada Test and Training Range (NTTR) and consists of one corrective action site: NAFR-23-02, Pu Contaminated Soil. The CAU 415 site consists of the atmospheric release of radiological contaminants to surface soil from the Project 57 safety experiment conducted in 1957. The safety experiment released plutonium (Pu), uranium (U), and americium (Am) to the surface soil over an area of approximately 1.9 square miles. This area is currently fenced and posted as a radiological contamination area. Vehicles and debris contaminated by the experiment were subsequently buried in a disposal trench within the surface-contaminated, fenced area and are assumed to have released radiological contamination to subsurface soils. Potential source materials in the form of pole-mounted electrical transformers were also identified at the site and will be removed as part of closure activities.
Mark Krauss
2010-03-01
This Streamlined Approach for Environmental Restoration Plan addresses the actions needed to achieve closure of Corrective Action Unit (CAU) 408, Bomblet Target Area (TTR). Corrective Action Unit 408 is located at the Tonopah Test Range and is currently listed in Appendix III of the Federal Facility Agreement and Consent Order. Corrective Action Unit 408 comprises Corrective Action Site TA-55-002-TAB2, Bomblet Target Areas. Clean closure of CAU 408 will be accomplished by removal of munitions and explosives of concern within seven target areas and potential disposal pits. The target areas were used to perform submunitions related tests for the U.S. Department of Energy (DOE). The scope of CAU 408 is limited to submunitions released from DOE activities. However, it is recognized that the presence of other types of unexploded ordnance and munitions may be present within the target areas due to the activities of other government organizations. The CAU 408 closure activities consist of: • Clearing bomblet target areas within the study area. • Identifying and remediating disposal pits. • Collecting verification samples. • Performing radiological screening of soil. • Removing soil containing contaminants at concentrations above the action levels. Based on existing information, contaminants of potential concern at CAU 408 include unexploded submunitions, explosives, Resource Conservation Recovery Act metals, and depleted uranium. Contaminants are not expected to be present in the soil at concentrations above the action levels; however, this will be determined by radiological surveys and verification sample results.
Saeed Abedi; Ali Akbar Dehghan; Ali Saeidinezhad; Mojtaba Dehghan Manshadi
2016-01-01
A flow field around a streamlined body at an intermediate angle of incidence is dominated by cross-flow separation and vortical flow fields. The separated flow leads to a pair of vortices on the leeside of the body; therefore, it is essential to accurately determine this pair and estimate its size and location. This study utilizes the element-based finite volume method based on RANS equations to compute a 3D axisymmetric flow around a SUBOFF bare submarined hull. Cross-flow vortex structures are then numerically simulated and compared for a submarine with SUBOFF and DRDC STR bows. Computed results of pressure and shear stress distribution on the hull surface and the strength and locations of the vortex structures are presented at an intermediate incidence angle of 20°. A wind tunnel experiment is also conducted to experimentally visualize the vortex structures and measure their core locations. These experimental results are compared with the numerical data, and a good agreement is found.
Matthews, Patrick [Navarro-Intera, LLC (N-I), Las Vegas, NV (United States)
2014-12-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 575, Area 15 Miscellaneous Sites, identified in the Federal Facility Agreement and Consent Order (FFACO). CAU 575 comprises the following four corrective action sites (CASs) located in Area 15 of the Nevada National Security Site: 15-19-02, Waste Burial Pit, 15-30-01, Surface Features at Borehole Sites, 15-64-01, Decontamination Area, 15-99-03, Aggregate Plant This plan provides the methodology for field activities needed to gather the necessary information for closing each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 575 using the SAFER process. Additional information will be obtained by conducting a field investigation to document and verify the adequacy of existing information, to affirm the predicted corrective action decisions, and to provide sufficient data to implement the corrective actions. This will be presented in a closure report that will be prepared and submitted to the Nevada Division of Environmental Protection (NDEP) for review and approval.
Matthews, Patrick K.
2015-04-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 412. CAU 412 is located on the Tonopah Test Range and consists of a single corrective action site (CAS), TA-23-01CS, Pu Contaminated Soil. There is sufficient information and historical documentation from previous investigations and the 1997 interim corrective action to recommend closure of CAU 412 using the SAFER process. Based on existing data, the presumed corrective action for CAU 412 is clean closure. However, additional data will be obtained during a field investigation to document and verify the adequacy of existing information and determine whether the CAU 412 closure objectives have been achieved. This SAFER Plan provides the methodology to gather the necessary information for closing the CAU.The following summarizes the SAFER activities that will support the closure of CAU 412:• Collect environmental samples from designated target populations to confirm or disprove the presence of contaminants of concern (COCs) as necessary to supplement existing information.• If no COCs are present, establish clean closure as the corrective action. • If COCs are present, the extent of contamination will be defined and further corrective actions will be evaluated with the stakeholders (NDEP, USAF).• Confirm the preferred closure option is sufficient to protect human health and the environment.
Chen, Zengsheng; Zhan, Fan; Ding, Jun; Zhang, Xiwen; Deng, Xiaoyan
2016-01-01
We proposed a new stent with streamlined cross-sectional wires, which is different from the clinical coronary stents with square or round cross-sections. We believe the new stent might have better hemodynamic performance than the clinical metal stents. To test the hypothesis, we designed an experimental study to compare the performance of the new stent with the clinical stents in terms of monocyte (U-937 cells) adhesion. The results showed that when compared with the clinical stents, the adhesion of U-937 cells were much less in the new stent. The results also showed that, when Reynolds number increased from 180 (the rest condition for the coronary arteries) to 360 (the strenuous exercise condition for the coronary arteries), the flow disturbance zones in the clinical stents became larger, while they became smaller with the new stent. The present experimental study therefore suggests that the optimization of the cross-sectional shape of stent wires ought to be taken into consideration in the design of endovascular stents.
Abedi, Saeed; Dehghan, Ali Akbar; Saeidinezhad, Ali; Manshadi, Mojtaba Dehghan
2016-03-01
A flow field around a streamlined body at an intermediate angle of incidence is dominated by cross-flow separation and vortical flow fields. The separated flow leads to a pair of vortices on the leeside of the body; therefore, it is essential to accurately determine this pair and estimate its size and location. This study utilizes the element-based finite volume method based on RANS equations to compute a 3D axisymmetric flow around a SUBOFF bare submarined hull. Cross-flow vortex structures are then numerically simulated and compared for a submarine with SUBOFF and DRDC STR bows. Computed results of pressure and shear stress distribution on the hull surface and the strength and locations of the vortex structures are presented at an intermediate incidence angle of 20°. A wind tunnel experiment is also conducted to experimentally visualize the vortex structures and measure their core locations. These experimental results are compared with the numerical data, and a good agreement is found.
Alfred Wickline
2006-04-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions necessary for the closure of Corrective Action Unit (CAU) 538: Spill Sites, Nevada Test Site, Nevada. It has been developed in accordance with the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996) that was agreed to by the State of Nevada, the U.S. Department of Energy (DOE), and the U.S. Department of Defense. A SAFER may be performed when the following criteria are met: (1) Conceptual corrective actions are clearly identified (although some degree of investigation may be necessary to select a specific corrective action before completion of the Corrective Action Investigation [CAI]). (2) Uncertainty of the nature, extent, and corrective action must be limited to an acceptable level of risk. (3) The SAFER Plan includes decision points and criteria for making data quality objective (DQO) decisions. The purpose of the investigation will be to document and verify the adequacy of existing information; to affirm the decision for either clean closure, closure in place, or no further action; and to provide sufficient data to implement the corrective action. The actual corrective action selected will be based on characterization activities implemented under this SAFER Plan. This SAFER Plan identifies decision points developed in cooperation with the Nevada Division of Environmental Protection (NDEP) and where DOE will reach consensus with NDEP before beginning the next phase of work.
Laloš, Jernej; Babnik, Aleš; Možina, Janez; Požar, Tomaž
2016-03-01
The near-field, surface-displacement waveforms in plates are modeled using interwoven concepts of Green's function formalism and streamlined Huygens' principle. Green's functions resemble the building blocks of the sought displacement waveform, superimposed and weighted according to the simplified distribution. The approach incorporates an arbitrary circular spatial source distribution and an arbitrary circular spatial sensitivity in the area probed by the sensor. The displacement histories for uniform, Gaussian and annular normal-force source distributions and the uniform spatial sensor sensitivity are calculated, and the corresponding weight distributions are compared. To demonstrate the applicability of the developed scheme, measurements of laser ultrasound induced solely by the radiation pressure are compared with the calculated waveforms. The ultrasound is induced by laser pulse reflection from the mirror-surface of a glass plate. The measurements show excellent agreement not only with respect to various wave-arrivals but also in the shape of each arrival. Their shape depends on the beam profile of the excitation laser pulse and its corresponding spatial normal-force distribution.
She, Hoi Lam; Roest, Arno A W; Calkoen, Emmeline E; van den Boogaard, Pieter J; van der Geest, Rob J; Hazekamp, Mark G; de Roos, Albert; Westenberg, Jos J M
2017-01-01
To evaluate the inflow pattern and flow quantification in patients with functional univentricular heart after Fontan's operation using 4D flow magnetic resonance imaging (MRI) with streamline visualization when compared with the conventional 2D flow approach. Seven patients with functional univentricular heart after Fontan's operation and twenty-three healthy controls underwent 4D flow MRI. In two orthogonal two-chamber planes, streamline visualization was applied, and inflow angles with peak inflow velocity (PIV) were measured. Transatrioventricular flow quantification was assessed using conventional 2D multiplanar reformation (MPR) and 4D MPR tracking the annulus and perpendicular to the streamline inflow at PIV, and they were validated with net forward aortic flow. Inflow angles at PIV in the patient group demonstrated wide variation of angles and directions when compared with the control group (P functional univentricular heart with previous Fontan's procedure. 4D flow aided generation of measurement planes according to the blood flood dynamics and has proven to be more accurate than the fixed plane 2D flow measurements when calculating flow quantifications. © 2016 Wiley Periodicals, Inc.
Matthews, Patrick K. [Navarro-Intera, LLC (N-I), Las Vegas, NV (United States)
2015-03-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 411, Double Tracks Plutonium Dispersion (Nellis). CAU 411 is located on the Nevada Test and Training Range and consists of a single corrective action site (CAS), NAFR-23-01, Pu Contaminated Soil. There is sufficient information and historical documentation from previous investigations and the 1996 interim corrective action to recommend closure of CAU 411 using the SAFER process. Based on existing data, the presumed corrective action for CAU 411 is clean closure. However, additional data will be obtained during a field investigation to document and verify the adequacy of existing information, and to determine whether the CAU 411 closure objectives have been achieved. This SAFER Plan provides the methodology to gather the necessary information for closing the CAU. The results of the field investigation will be presented in a closure report that will be prepared and submitted to the Nevada Division of Environmental Protection (NDEP) for review and approval. The site will be investigated based on the data quality objectives (DQOs) developed on November 20, 2014, by representatives of NDEP, the U.S. Air Force (USAF), and the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office. The DQO process was used to identify and define the type, amount, and quality of data needed to determine whether CAU 411 closure objectives have been achieved. The following text summarizes the SAFER activities that will support the closure of CAU 411; Collect environmental samples from designated target populations to confirm or disprove the presence of contaminants of concern (COCs) as necessary to supplement existing information; If COCs are no longer present, establish clean closure as the corrective action; If COCs are present, the extent of contamination will be defined and further corrective actions
T. M. Fitzmaurice
2001-08-01
This Streamlined Approach for Environmental restoration (SAFER) plan addresses the action necessary for the closure of Corrective Action Unit (CAU) 330, Areas 6,22, and 23 Tanks and Spill Sites. The CAUs are currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO). This CAU is located at the Nevada Test Site (NTS) (Figure 1). CAU 330 consists of the following Corrective Action Sites (CASs): (1) CAS 06-02-04 - Consists of an underground tank and piping. This CAS is close to an area that was part of the Animal Investigation Program (AIP), conducted under the U.S. Public Health Service. Its purpose was to study and perform tests on the cattle and wild animals in and around the NTS that were exposed to radionuclides. It is unknown if this tank was part of these operations. (2) CAS 22-99-06 - Is a fuel spill that is believed to be a waste oil release which occurred when Camp Desert Rock was an active facility. This CAS was originally identified as being a small depression where liquids were poured onto the ground, located on the west side of Building T-1001. This building has been identified as housing a fire station, radio station, and radio net remote and telephone switchboard. (3) CAS 23-01-02 - Is a large aboveground storage tank (AST) farm that was constructed to provide gasoline and diesel storage in Area 23. The site consists of two ASTs, a concrete foundation, a surrounding earthen berm, associated piping, and unloading stations. (4) CAS 23-25-05 - Consists of an asphalt oil spill/tar release that contains a wash covered with asphalt oil/tar material, a half buried 208-liter (L) (55-gallon [gal]) drum, rebar, and concrete located in the vicinity.
Ashraf Abualhassan Abdellatif
2011-01-01
Full Text Available Context: Supraglottic airway devices have been used as an alternative to tracheal intubation during laparoscopic surgery. Aims: The study was designed to compare the efficacy of Streamlined Liner of the Pharynx Airway (SLIPA for positive pressure ventilation and postoperative complications with the Laryngeal Mask Airway ProSeal (PLMA for patients undergoing lower abdominal laparoscopies under general anesthesia with controlled ventilation. Settings and Design: Prospective, crossover randomized controlled trial performed on patients undergoing lower abdominal laparoscopic surgeries. Methods: A total of 120 patients undergoing lower abdominal laparoscopic surgeries were randomly allocated into two equal groups; PLMA and SLIPA groups. Number of intubation attempts, insertion time, ease of insertion, and fiberoptic bronchoscopic view were recorded. Lung mechanics data were collected 5 minutes after securing the airway, then after abdominal insufflation. Blood traces and regurgitation were checked for; postoperative sore throat and other complications were recorded. Statistical Analysis: Arithmetic mean and standard deviation values were calculated and statistical analyses were performed for each group. Independent sample t-test was used to compare continuous variables exhibiting normal distribution, and Chi-squared test for noncontinuous variables. P value <0.05 was considered significant. Results: Insertion time, first insertion success rate, and ease of insertion were comparable in both groups. Fiberoptic bronchoscopic view was significantly better and epiglottic downfolding was significantly lower in SLIPA group. Sealing pressure and lung mechanics were similar. Gastric distension was not observed in both groups. Postoperative sore throat was significantly higher in PACU in PLMA group. Blood traces on the device were significantly more in SLIPA group. Conclusions: SLIPA can be used as a useful alternative to PLMA in patients undergoing lower
A. T. Urbon
2001-09-01
This Streamlined Approach for Environmental Restoration (SAFER) plan addresses the action necessary for the closure of Corrective Action Unit (CAU) 326, Areas 6 and 27 Release Sites. This CAU is currently listed in the January 2001, Appendix III of the Federal Facilities Agreement and Consent Order (FFACO) (FFACO, 1996). CAU 326 is located on the Nevada Test Site (NTS) and consists of the following four Corrective Action Sites (CASS) (Figure 1): CAS 06-25-01--Is a rupture in an underground pipe that carried heating oil (diesel) from the underground heating oil tank (Tank 6-CP-1) located to the west of Building CP-70 to the boiler in Building CP-1 in the Area 6 Control Point (CP) compound. CAS 06-25-02--A heating oil spill that is a result of overfilling an underground heating oil tank (Tank 6-DAF-5) located at the Area 6 Device Assembly Facility (DAF). CAS 06-25-04--A release of waste oil that occurred while removing used oil to from Tank 6-619-4. Tank 6-619-4 is located northwest of Building 6-619 at the Area 6 Gas Station. CAS 27-25-01--Consists of an excavation that was created in an attempt to remove impacted stained soil from the Site Maintenance Yard in Area 27. Approximately 53.5 cubic meters (m{sup 3}) (70 cubic yards [yd{sup 3}]) of soil impacted by total petroleum hydrocarbons (TPH) and polychlorinated biphenyls (PCBs) was excavated before the excavation activities were halted. The excavation activities were stopped because the volume of impacted soil exceeded estimated quantities and budget.
Pat Matthews
2007-09-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 117, Pluto Disassembly Facility, identified in the Federal Facility Agreement and Consent Order. Corrective Action Unit 117 consists of one Corrective Action Site (CAS), CAS 26-41-01, located in Area 26 of the Nevada Test Site. This plan provides the methodology for field activities needed to gather the necessary information for closing CAS 26-41-01. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 117 using the SAFER process. Additional information will be obtained by conducting a field investigation before finalizing the appropriate corrective action for this CAS. The results of the field investigation will support a defensible recommendation that no further corrective action is necessary following SAFER activities. This will be presented in a Closure Report that will be prepared and submitted to the Nevada Division of Environmental Protection (NDEP) for review and approval. The site will be investigated to meet the data quality objectives (DQOs) developed on June 27, 2007, by representatives of NDEP; U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office; Stoller-Navarro Joint Venture; and National Security Technologies, LLC. The DQO process was used to identify and define the type, amount, and quality of data needed to determine and implement appropriate corrective actions for CAS 26-41-01 in CAU 117.
David Strand
2006-09-01
This Streamlined Approach for Environmental Restoration (SAFER) plan addresses closure for Corrective Action Unit (CAU) 118, Area 27 Super Kukla Facility, identified in the ''Federal Facility Agreement and Consent Order''. Corrective Action Unit 118 consists of one Corrective Action Site (CAS), 27-41-01, located in Area 27 of the Nevada Test Site. Corrective Action Site 27-41-01 consists of the following four structures: (1) Building 5400A, Reactor High Bay; (2) Building 5400, Reactor Building and access tunnel; (3) Building 5410, Mechanical Building; and (4) Wooden Shed, a.k.a. ''Brock House''. This plan provides the methodology for field activities needed to gather the necessary information for closing the CAS. There is sufficient information and process knowledge from historical documentation and site confirmation data collected in 2005 and 2006 to recommend closure of CAU 118 using the SAFER process. The Data Quality Objective process developed for this CAU identified the following expected closure option: closure in place with use restrictions. This expected closure option was selected based on available information including contaminants of potential concern, future land use, and assumed risks. There are two decisions that need to be answered for closure. Decision I is to determine the nature of contaminants of concern in environmental media or potential source material that could impact human health or the environment. Decision II is to determine whether or not sufficient information has been obtained to confirm that closure objectives were met. This decision includes determining whether the extent of any contamination remaining on site has been defined, and whether actions have been taken to eliminate exposure pathways.
Yang, Song; Sadilek, Martin; Lidstrom, Mary E
2010-11-19
Streamlined quantitative metabolomics in central metabolism of bacteria would be greatly facilitated by a high-efficiency liquid chromatography (LC) method in conjunction with accurate quantitation. To achieve this goal, a methodology for LC-tandem quadrupole mass spectrometry (LC-MS/MS) involving a pentafluorophenylpropyl (PFPP) column and culture-derived global (13)C-labeled internal standards (I.Ss.) has been developed and compared to hydrophilic interaction liquid chromatography (HILIC)-MS/MS and published combined two-dimensional gas chromatography and LC methods. All 50 tested metabolite standards from 5 classes (amino acids, carboxylic acids, nucleotides, acyl-CoAs and sugar phosphates) displayed good chromatographic separation and sensitivity on the PFPP column. In addition, many important critical pairs such as isomers/isobars (e.g. isoleucine/leucine, methylsuccinic acid/ethylmalonic acid and malonyl-CoA/3-hydroxybutyryl-CoA) and metabolites of similar structure (e.g. malate/fumarate) were resolved better on the PFPP than on the HILIC column. Compared to only one (13)C-labeled I.S., the addition of global (13)C-labeled I.Ss. improved quantitative linearity and accuracy. PFPP-MS/MS with global (13)C-labeled I.Ss. allowed the absolute quantitation of 42 metabolite pool sizes in Methylobacterium extorquens AM1. A comparison of metabolite level changes published previously for ethylamine (C2) versus succinate (C4) cultures of M. extorquens AM1 indicated a good consistency with the data obtained by PFPP-MS/MS, suggesting this single approach has the capability of providing comprehensive metabolite profiling similar to the combination of methods. The more accurate quantification obtained by this method forms a fundamental basis for flux measurements and can be used for metabolism modeling in bacteria in future studies. Published by Elsevier B.V.
Streamlining Iron and Steel Production
2008-01-01
Eliminating unproductive iron and steel facilities is vital to environmental protection and sustainable development of this industry The Chinese Government is once again shutting down unproductive plants in tune with its green policy and the march toward sustainable development.This time it’s the iron and steel industry to feel the brunt of the Chinese Government’s stringent measures. The deafening buzz of factory floors have
Organic chemistry: Streamlining drug synthesis
Hawkins, Joel M.
2015-04-01
Drug manufacture can benefit from flow synthesis, in which raw materials are fed into a sequence of reactors, producing the drug as a continuous output. A flow strategy that capitalizes on solid catalysts has now been realized. See Letter p.329
Streamlining Smart Meter Data Analytics
Liu, Xiufeng; Nielsen, Per Sieverts
2015-01-01
with the complexity of data processing and data analytics. The system offers an information integration pipeline to ingest smart meter data; scalable data processing and analytic platform for pre-processing and mining big smart meter data sets; and a web-based portal for visualizing data analytics results. The system......Today smart meters are increasingly used in worldwide. Smart meters are the advanced meters capable of measuring customer energy consumption at a fine-grained time interval, e.g., every 15 minutes. The data are very sizable, and might be from different sources, along with the other social......-economic metrics such as the geographic information of meters, the information about users and their property, geographic location and others, which make the data management very complex. On the other hand, data-mining and the emerging cloud computing technologies make the collection, management, and analysis...
Streamline topology of axisymmetric flows
Brøns, Morten
Topological fluid mechanics in the sense of the present paper is the study and classification of flow patterns close to a critical point. Here we discuss the topology of steady viscous incompressible axisymmetric flows in the vicinity of the axis. Following previous studies the velocity field $v......$ is expanded in a Taylor series at a point on the axis, and the expansion coefficients are considered as bifurcation parameters. After a normal form transformation we easily obtain the most common bifurcations of the flow patterns. The use of non-linear normal forms provide a gross simplification, which...... to the authors knowledge has not been used systematically to high orders in topological fluid mechanics. We compare the general results with experimental and computational results on the Vogel-Ronneberg flow. We show that the topology changes observed when recirculating bubbles on the vortex axis are created...
Streamlining Safety Testing for Munitions
1994-08-18
considerations. By comparison, a gas fire is cleaner and its outcome can be much more informative: - because the fire can stopped immediately after...the event; - and because its flame is transparent. Now, precisely because its flame is transparent, a gas fire differs from a fuel fire: gas flame...experimental inputs provided these are of good quality and their boundary conditions well defined, which is certainly easier to obtain with a gas fire than
Software Tools Streamline Project Management
2009-01-01
Three innovative software inventions from Ames Research Center (NETMARK, Program Management Tool, and Query-Based Document Management) are finding their way into NASA missions as well as industry applications. The first, NETMARK, is a program that enables integrated searching of data stored in a variety of databases and documents, meaning that users no longer have to look in several places for related information. NETMARK allows users to search and query information across all of these sources in one step. This cross-cutting capability in information analysis has exponentially reduced the amount of time needed to mine data from days or weeks to mere seconds. NETMARK has been used widely throughout NASA, enabling this automatic integration of information across many documents and databases. NASA projects that use NETMARK include the internal reporting system and project performance dashboard, Erasmus, NASA s enterprise management tool, which enhances organizational collaboration and information sharing through document routing and review; the Integrated Financial Management Program; International Space Station Knowledge Management; Mishap and Anomaly Information Reporting System; and management of the Mars Exploration Rovers. Approximately $1 billion worth of NASA s projects are currently managed using Program Management Tool (PMT), which is based on NETMARK. PMT is a comprehensive, Web-enabled application tool used to assist program and project managers within NASA enterprises in monitoring, disseminating, and tracking the progress of program and project milestones and other relevant resources. The PMT consists of an integrated knowledge repository built upon advanced enterprise-wide database integration techniques and the latest Web-enabled technologies. The current system is in a pilot operational mode allowing users to automatically manage, track, define, update, and view customizable milestone objectives and goals. The third software invention, Query-Based Document Management (QBDM) is a tool that enables content or context searches, either simple or hierarchical, across a variety of databases. The system enables users to specify notification subscriptions where they associate "contexts of interest" and "events of interest" to one or more documents or collection(s) of documents. Based on these subscriptions, users receive notification when the events of interest occur within the contexts of interest for associated document or collection(s) of documents. Users can also associate at least one notification time as part of the notification subscription, with at least one option for the time period of notifications.
Boehlecke, Robert F.
2006-11-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions necessary for the closure of Corrective Action Unit (CAU) 553: Areas 19, 20 Mud Pits and Cellars, Nevada Test Site (NTS), Nevada. It has been developed in accordance with the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996) that was agreed to by the State of Nevada, the U.S. Department of Energy (DOE), and the U.S. Department of Defense. A SAFER may be performed when the following criteria are met: (1) Conceptual corrective actions are clearly identified (although some degree of investigation may be necessary to select a specific corrective action before completion of the Corrective Action Investigation [CAI]); (2) Uncertainty of the nature, extent, and corrective action must be limited to an acceptable level of risk; (3) The SAFER Plan includes decision points and criteria for making data quality objective (DQO) decisions. The purpose of the investigation will be to document and verify the adequacy of existing information; to affirm the decision for clean closure, closure in place, or no further action; and to provide sufficient data to implement the corrective action. The actual corrective action selected will be based on characterization activities implemented under this SAFER Plan. This SAFER Plan identifies decision points developed in cooperation with the Nevada Department of Environmental Protection (NDEP), where the DOE, National Nuclear Security Administration Nevada Site Office (NNSA/NSO) will reach consensus with the NDEP before beginning the next phase of work. Corrective Action Unit 553 is located in Areas 19 and 20 of the NTS, approximately 65 miles (mi) northwest of Las Vegas, Nevada (Figure 1-1). Corrective Action Unit 553 is comprised of the four Corrective Action Sites (CASs) shown on Figure 1-1 and listed below: 19-99-01, Mud Spill; 19-99-11, Mud Spill; 20-09-09, Mud Spill; and 20-99-03, Mud Spill. There is sufficient
TIAN Xiao-pei; SHAN Peng
2013-01-01
Two strategies extended the single-cascade methods from a compressible three-dimensional inverse method for radial and mixed flow turbomachines to two three dimensional multi-cascade co-design methods for single-stage centrifugal compressors.These two three dimensional methods and a typical quasi-threedimensional streamline curvature through-flow inverse method were employed to design the same subsonic high-speed single-stage centrifugal compressors.The compressor performances were simulated by a commercial Reynolds averaged Navier-Stokes (RANS) equations solver.The studies show that two three-dimensional codesign methods are reasonable and feasible.It was found that:firstly the blade camber angle designed by the three-dimensional methods was larger than that designed by the quasi-three-dimensional method;and secondly with regard to two three-dimensional methods with different boundary conditions,the co-design result differences between the diffusers were small,but those between the deswirlers were relatively large.
Hartop, Emily A; Brown, Brian V
2014-01-01
A new Megaselia species, M.shadeae, with a large, central, pigmented and bubble-like wing spot and a greatly enlarged radial wing vein fork, is described from Zurquí de Moravia, Costa Rica. As part of the Zurquí All Diptera Biodiversity Inventory (ZADBI) project, it represents the first of an incredible number of new phorid species to be described from this one Costa Rican cloud forest site. A new, streamlined method of description for species of this enormous genus of phorid flies is presented.
Emily Hartop; Brian Brown
2014-01-01
Abstract A new Megaselia species, M. shadeae , with a large, central, pigmented and bubble-like wing spot and a greatly enlarged radial wing vein fork, is described from Zurquí de Moravia, Costa Rica. As part of the Zurquí All Diptera Biodiversity Inventory (ZADBI) project, it represents the first of an incredible number of new phorid species to be described from this one Costa Rican cloud forest site. A new, streamlined method of description for species of this enormous genus of phorid flies...
Emily Hartop
2014-11-01
Full Text Available A new Megaselia species, M. shadeae, with a large, central, pigmented and bubble-like wing spot and a greatly enlarged radial wing vein fork, is described from Zurquí de Moravia, Costa Rica. As part of the Zurquí All Diptera Biodiversity Inventory (ZADBI project, it represents the first of an incredible number of new phorid species to be described from this one Costa Rican cloud forest site. A new, streamlined method of description for species of this enormous genus of phorid flies is presented.
Patrick Matthews
2011-11-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 465, Hydronuclear, identified in the Federal Facility Agreement and Consent Order (FFACO). Corrective Action Unit 465 comprises the following four corrective action sites (CASs) located in Areas 6 and 27 of the Nevada National Security Site: (1) 00-23-01, Hydronuclear Experiment; (2) 00-23-02, Hydronuclear Experiment; (3) 00-23-03, Hydronuclear Experiment; (4) 06-99-01, Hydronuclear. The sites will be investigated based on the data quality objectives (DQOs) developed on July 6, 2011, by representatives of the Nevada Division of Environmental Protection (NDEP) and the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office. The DQO process was used to identify and define the type, amount, and quality of data needed to determine and implement appropriate corrective actions for each CAS in CAU 465. For CAU 465, two potential release components have been identified. The subsurface release component includes potential releases of radiological and nonradiological contaminants from the subsurface hydronuclear experiments and disposal boreholes. The surface release component consists of other potential releases of radiological and nonradiological contaminants to surface soils that may have occurred during the pre- and post-test activities. This plan provides the methodology for collection of the necessary information for closing each CAS component. There is sufficient information and process knowledge from historical documentation, contaminant characteristics, existing regional and site groundwater models, and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 465 using the SAFER process. For potential subsurface releases, flow and transport models will be developed to integrate existing data into a conservative
Alfred Wickline
2006-06-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses closure for Corrective Action Unit (CAU) 177, Mud Pits and Cellars, identified in the ''Federal Facility Agreement and Consent Order''. Corrective Action Unit 177 consists of the 12 following Corrective Action Sites (CASs) located in Areas 8, 9, 19, and 20 of the Nevada Test Site: (1) 08-23-01, Mud Pit and Cellar; (2) 09-09-41, Unknown No.3 Mud Pit/Disposal Area; (3) 09-09-45, U-9bz PS No.1A Mud Pit (1) and Cellar; (4) 09-23-05, Mud Pit and Cellar; (5) 09-23-08, Mud Pit and Cellar; (6) 09-23-09, U-9itsx20 PS No.1A Cellar; (7) 10-23-02, Mud Pit and Cellar; (8) 10-23-03, Mud Pit and Cellar; (9) 19-23-01, Mud Pit and Cellar; (10) 19-23-02, Cellar and Waste Storage Area; (11) 19-23-03, Cellar with Casing; and (12) 20-23-07, Cellar. This plan provides the methodology for field activities needed to gather the necessary information for closing each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 177 using the SAFER process. The data quality objective process developed for this CAU identified the following expected closure options: (1) investigation and confirmation that no contamination exists above the preliminary action levels (PALs), leading to a no further action declaration, or (2) characterization of the nature and extent of contamination, leading to closure in place with use restrictions. The expected closure options were selected based on available information including contaminants of potential concern, future land use, and assumed risks. A decision flow process was developed to outline the collection of data necessary to achieve closure. There are two decisions that need to be answered for closure. Decision I is to determine whether contaminants of potential concern are present in concentrations
Mark Krauss
2010-06-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 539, Areas 25 and 26 Railroad Tracks, as identified in the Federal Facility Agreement and Consent Order (FFACO). A modification to the FFACOwas approved in May 2010 to transfer the two Railroad Tracks corrective action sites (CASs) from CAU 114 into CAU539. The two CASs are located in Areas 25 and 26 of the Nevada Test Site: • 25-99-21, Area 25 Railroad Tracks • 26-99-05, Area 26 Railroad Tracks This plan provides the methodology for field activities needed to gather the necessary information for closing the two CASs. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of the CAU 539 Railroad Tracks CASs using the SAFER process. Additional information will be obtained by conducting a field investigation before selecting the appropriate corrective action for each CAS. The results of the field investigation should support a defensible recommendation that no further corrective action is necessary. If it is determined that complete clean closure cannot be accomplished during the SAFER, then a hold point will have been reached and the Nevada Division of Environmental Protection (NDEP) will be consulted to determine whether the remaining contamination will be closed under the alternative corrective action of closure in place with use restrictions. This will be presented in a closure report that will be prepared and submitted to the NDEP for review and approval. The sites will be investigated based on the data quality objectives (DQOs) developed on December 14, 2009, by representatives of U.S.Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office; Navarro Nevada Environmental Services, LLC (NNES); and National Security Technologies
U.S. Department of Energy, National Nuclear Security Administration Nevada Operations Office (NNSA/NV)
2001-08-21
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions necessary for the characterization and closure of Corrective Action Unit (CAU) 356, Mud Pits and Disposal Sites, as identified in the Federal Facility Agreement and Consent Order (FFACO). The CAU, located on the Nevada Test Site in Nevada, consists of seven Corrective Action Sites (CASs): CAS 03-04-01, Area 3 Change House Septic System; CAS 03-09-01, Mud Pit Spill Over; CAS 03-09-03, Mud Pit; CAS 03-09-04, Mud Pit; CAS 03-09-05, Mud Pit; CAS 20-16-01, Landfill; CAS 20-22-21, Drums. Sufficient information and process knowledge from historical documentation and investigations are the basis for the development of the phased approach chosen to address the data collection activities prior to implementing the preferred closure alternative for each CAS. The Phase I investigation will determine through collection of environmental samples from targeted populations (i.e., mud/soil cuttings above textural discontinuity) if contaminants of potential concern (COPCs) are present in concentrations exceeding preliminary action levels (PALs) at each of the CASs. If COPCs are present above PALs, a Phase II investigation will be implemented to determine the extent of contamination to support the appropriate corrective action alternative to complete closure of the site. Groundwater impacts from potentially migrating contaminants are not expected due to the depths to groundwater and limiting hydrologic drivers of low precipitation and high evaporation rates. Future land-use scenarios limit future uses to industrial activities; therefore, future residential uses are not considered. Potential exposure routes to site workers from contaminants of concern in septage and soils include oral ingestion, inhalation, or dermal contact (absorption) through in-advertent disturbance of contaminated structures and/or soils. Diesel within drilling muds is expected to be the primary COPC based on process
Mark Burmeister
2009-08-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 114, Area 25 EMAD Facility, identified in the Federal Facility Agreement and Consent Order (FFACO). Corrective Action Unit 114 comprises the following corrective action sites (CASs) located in Area 25 of the Nevada Test Site: • 25-41-03, EMAD Facility • 25-99-20, EMAD Facility Exterior Releases This plan provides the methodology for field activities needed to gather the necessary information for closing each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 114 using the SAFER process. Additional information will be obtained by conducting a field investigation before selecting the appropriate corrective action for each CAS. It is anticipated that the results of the field investigation and implementation of a corrective action of clean closure will support a defensible recommendation that no further corrective action is necessary. If it is determined that complete clean closure cannot be accomplished during the SAFER, then a hold point will have been reached and the Nevada Division of Environmental Protection (NDEP) will be consulted to determine whether the remaining contamination will be closed under the alternative corrective action of closure in place. This will be presented in a closure report that will be prepared and submitted to NDEP for review and approval. The sites will be investigated based on the data quality objectives (DQOs) developed on April 30, 2009, by representatives of NDEP; U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office; Stoller-Navarro Joint Venture; and National Security Technologies, LLC. The DQO process was used to identify and define the type, amount, and quality of data
STABILIZED FINITE ELEMENT METHODS FOR THE BRINKMAN EQUATION ON FITTED AND FICITITIOUS DOMAINS
Sogn, Jarle
2014-01-01
The parameter dependent Brinkman equation can be used to model viscous and porous flow. The equation covers a family of problems, ranging from the Stokes problem to the Darcy problem. We apply the stabilization methods; the pressure stabilized petrov--galerkin (PSPG) method and the continuous interior penalty (CIP) method, on the Brinkman equation with weakly imposed boundary conditions by the Nitsche method. An a priori error estimate is proved for the CIP stabilization with the Nitsche meth...
Characteristic-Based Split Meshless Solution for Couette Flow
Mužík Juraj
2014-05-01
Full Text Available The paper deals with use of the meshless method for incompressible fluid flow analysis. There are many formulations of the meshless methods. The article presents the Meshless Local Petrov-Galerkin method (MLPG - local weak formulation of the Navier-Stokes equations. The shape function construction is the crucial part of the meshless numerical analysis in the construction of shape functions. The article presents the radial point interpolation method (RPIM for the shape functions construction
Mark Krauss
2010-07-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 544, Cellars, Mud Pits, and Oil Spills, identified in the Federal Facility Agreement and Consent Order (FFACO). Corrective Action Unit 544 comprises the following 20 corrective action sites (CASs) located in Areas 2, 7, 9, 10, 12, 19, and 20 of the Nevada Test Site (NTS): • 02-37-08, Cellar & Mud Pit • 02-37-09, Cellar & Mud Pit • 07-09-01, Mud Pit • 09-09-46, U-9itsx20 PS #1A Mud Pit • 10-09-01, Mud Pit • 12-09-03, Mud Pit • 19-09-01, Mud Pits (2) • 19-09-03, Mud Pit • 19-09-04, Mud Pit • 19-25-01, Oil Spill • 19-99-06, Waste Spill • 20-09-01, Mud Pits (2) • 20-09-02, Mud Pit • 20-09-03, Mud Pit • 20-09-04, Mud Pits (2) • 20-09-06, Mud Pit • 20-09-07, Mud Pit • 20-09-10, Mud Pit • 20-25-04, Oil Spills • 20-25-05, Oil Spills This plan provides the methodology for field activities needed to gather the necessary information for closing each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 544 using the SAFER process. Using the approach approved for previous mud pit investigations (CAUs 530–535), 14 mud pits have been identified that • are either a single mud pit or a system of mud pits, • are not located in a radiologically posted area, and • have no evident biasing factors based on visual inspections. These 14 mud pits are recommended for no further action (NFA), and further field investigations will not be conducted. For the sites that do not meet the previously approved closure criteria, additional information will be obtained by conducting a field investigation before selecting the appropriate corrective action for each CAS. The results of the field investigation will support a defensible
NSTec Environmental Restoration
2008-12-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan identifies the activities required for the closure of Corrective Action Unit (CAU) 116, Area 25 Test Cell C Facility. The Test Cell C (TCC) Facility is located in Area 25 of the Nevada Test Site (NTS) approximately 25 miles northwest of Mercury, Nevada (Figure 1). CAU 116 is currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO) of 1996 (as amended February 2008) and consists of two Corrective Action Sites (CASs): (1) CAS 25-23-20, Nuclear Furnace Piping; and (2) CAS 25-41-05, Test Cell C Facility. CAS 25-41-05 is described in the FFACO as the TCC Facility but actually includes Building 3210 and attached concrete shield wall only. CAU 116 will be closed by demolishing Building 3210, the attached concrete shield wall, and the nuclear furnace piping. In addition, as a best management practice (BMP), Building 3211 (moveable shed) will be demolished due to its close proximity to Building 3210. This will aid in demolition and disposal operations. Radiological surveys will be performed on the demolition debris to determine the proper disposal pathway. As much of the demolition debris as space allows will be placed into the Building 3210 basement structure. After filling to capacity with demolition debris, the basement structure will be mounded or capped and closed with administrative controls. Prior to beginning demolition activities and according to an approved Sampling and Analysis Plan (SAP), representative sampling of surface areas that are known, suspected, or have the potential to contain hazardous constituents such as lead or polychlorinated biphenyls (PCBs) will be performed throughout all buildings and structures. Sections 2.3.2, 4.2.2.2, 4.2.2.3, 4.3, and 6.2.6.1 address the methodologies employed that assure the solid debris placed in the basement structure will not contain contaminants of concern (COCs) above hazardous waste levels. The anticipated post
周俊明; 金大永; 张书华
2007-01-01
This paper is devoted to studying the superconvergence of streamline diffusion finite element methods for convection-diffusion problems. In [8], under the condition that ε≤ h2 the optimal finite element error estimate was obtained in L2-norm. In the present paper, however, the same error estimate result is gained under the weaker condition that ε≤h.
US House of Representatives, 2011
2011-01-01
The purpose of this hearing was to shed light on wasteful federal government spending. At a time when the nation faces a historic fiscal crisis, everyone must make a concerted effort to reduce federal spending. A necessary step in this process is to eliminate and streamline federal programs. Now more than ever, it is critical to ensure taxpayer…
On High-Order Upwind Methods for Advection
Huynh, H. T.
2017-01-01
In the fourth installment of the celebrated series of five papers entitled "Towards the ultimate conservative difference scheme", Van Leer (1977) introduced five schemes for advection, the first three are piecewise linear, and the last two, piecewise parabolic. Among the five, scheme I, which is the least accurate, extends with relative ease to systems of equations in multiple dimensions. As a result, it became the most popular and is widely known as the MUSCL scheme (monotone upstream-centered schemes for conservation laws). Schemes III and V have the same accuracy, are the most accurate, and are closely related to current high-order methods. Scheme III uses a piecewise linear approximation that is discontinuous across cells, and can be considered as a precursor of the discontinuous Galerkin methods. Scheme V employs a piecewise quadratic approximation that is, as opposed to the case of scheme III, continuous across cells. This method is the basis for the on-going "active flux scheme" developed by Roe and collaborators. Here, schemes III and V are shown to be equivalent in the sense that they yield identical (reconstructed) solutions, provided the initial condition for scheme III is defined from that of scheme V in a manner dependent on the CFL number. This equivalence is counter intuitive since it is generally believed that piecewise linear and piecewise parabolic methods cannot produce the same solutions due to their different degrees of approximation. The finding also shows a key connection between the approaches of discontinuous and continuous polynomial approximations. In addition to the discussed equivalence, a framework using both projection and interpolation that extends schemes III and V into a single family of high-order schemes is introduced. For these high-order extensions, it is demonstrated via Fourier analysis that schemes with the same number of degrees of freedom ?? per cell, in spite of the different piecewise polynomial degrees, share the same sets of eigenvalues and thus, have the same stability and accuracy. Moreover, these schemes are accurate to order 2??-1, which is higher than the expected order of ??.
Hiking strap force decreases during sustained upwind sailing
Buchardt, R; Bay, Jonathan; Bojsen-Møller, Jens
2017-01-01
of the study, hMVC was measured dry land in a hiking bench and correlated with the overall results at a national championship. Hiking strap force decreased from the first to the last minute in both 10 min sailing periods (430 ± 131 vs. 285 ± 130 N, P ... causes sailing-specific fatigue as evidenced by a marked reduction in exerted hiking strap force. However, MVC of the knee extensors was not compromised ∼45 s after hiking was terminated. Additionally, sailing performance is related to maximal hiking force....
Upwind design basis (WP4: offshore foundations and support structures)
Fischer, T.; De Vries, W.E.; Schmidt, B.
2010-01-01
The presented design basis gives a summarized overview of relevant design properties for a later offshore wind turbine design procedures within work package 4. The described offshore site is located in the Dutch North Sea and has a water depth of 21m. Therefore it will be chosen as shallow site with
曹金良; 阮骆阳; 郑英文; 许晓梦; 杨作天; 巫宇丛
2011-01-01
目的:评价SLIPA喉罩应用于全身麻醉下乳癌手术气道管理的效果.方法:择期乳癌手术患者80例,AsA分级Ⅰ或Ⅱ级,年龄38-65岁,体重42-83kg,Mallampatis分级Ⅰ或Ⅱ级,随机均分为两组(n=40):SLIPA喉罩组(S组)、ProSeal喉罩组(P组).麻醉诱导后置入喉罩,行机械通气.记录手术时间、清醒时间、喉罩置入时间、置入成功率、置入喉罩前后MAP、HR的变化以及拔除喉罩时呛咳、返流、误吸及喉痉挛、术毕咽喉疼痛情况.结果:两组手术时间、清醒时间比较差异无统计学意义(P>0.05).置入喉罩期间两组MAP、HR组间比较差异无统计学意义(P>0.05).S组置入喉罩时间短于P组(P<0.05),S组一次置入喉罩成功率高于P组,差异有统计学意义(P<0.05).两组反流、误吸及喉痉挛的发生率差异无统计学意义.而S组术后喉罩带血、咽痛发生率较P组有所降低(P<0.05).结论:SLIPA喉罩通气效果好,易于置入,且对咽喉损伤较小,可安全有效用于乳癌手术患者的气道管理.%Objective: To assess the efficacy of streamlined liner pharynx airway (SLIPA) used in patients undergoing breast carcinoma surgery. Method: Eighty patients by ASA Ⅰ or Ⅱ, aged 38-65 ,weighing 42-83kg, undergoing selective breast carcinoma surgery, were randomized into two groups (n =40 each):streamlined liner pharynx airway group( group S ) and ProSeal largneal mask airway group( group P). Mallampati test was performed before operation in both groups. The patients were classified as Ⅰ or Ⅱ Streamlined liner pharynx airway and ProSeal laryngeal mask airway were inserted in group S and group P respectively after induction anesthesia. The number of attempt , success rate , LMA placement time were recorded, Mean arterial pressure( MAP) ,heart rate( HR) were recorded before and after LMA placement . Complications and the duration of surgery and emergence time were also recorded. Result:There＇s no significant differences in the
Provatas, Anthony A; Yevdokimov, Alexander V; King, Cory A; Gatley, Emma L; Stuart, James D; Evers, David C; Perkins, Christopher R
2015-08-01
A streamlined method has been developed for the isolation and analysis of polycyclic aromatic hydrocarbons in avian blood cells and plasma utilizing quick, easy, cheap, effective, rugged, and safe extraction in combination with novel phospholipid cleanup technology. A variety of traditional extraction and cleanup techniques have been employed in the preparation and analysis of polycyclic aromatic hydrocarbonsin a variety of matrices; liquid-liquid partitioning, solid-phase extractions, gel permeation chromatography, and column chromatography are all effective techniques, however they are laborious and time consuming processes that require large amounts of solvent. Using quick, easy, cheap, effective, rugged, and safe extraction coupled with phospholipid cleanup, samples can be quickly screened while maintaining high throughput and sensitivity. With a liquid chromatography approach, analysis times may be kept short at 16 min while maintaining high analyte recovery. Recoveries in quality control samples ranged from 70 to 109%, with average surrogate recoveries of 80.6 ± 1.10%. The result of using a quick, easy, cheap, effective, rugged, and safe extraction approach in conjunction with phospholipid cleanup is a methodology that significantly reduces sample preparation time and solvent use while maintaining high sensitivity and reproducibility.
None
2003-06-25
This Streamlined Approach for Environmental Restoration (SAFER) plan was prepared as a characterization and closure report for Corrective Action Unit (CAU) 357, Mud Pits and Waste Dump, in accordance with the Federal Facility Agreement and Consent Order. The CAU consists of 14 Corrective Action Sites (CASs) located in Areas 1, 4, 7, 8, 10, and 25 of the Nevada Test Site (NTS). All of the CASs are found within Yucca Flat except CAS 25-15-01 (Waste Dump). Corrective Action Site 25-15-01 is found in Area 25 in Jackass Flat. Of the 14 CASs in CAU 357, 11 are mud pits, suspected mud pits, or mud processing-related sites, which are by-products of drilling activities in support of the underground nuclear weapons testing done on the NTS. Of the remaining CASs, one CAS is a waste dump, one CAS contains scattered lead bricks, and one CAS has a building associated with Project 31.2. All 14 of the CASs are inactive and abandoned. Clean closure with no further action of CAU 357 will be completed if no contaminants are detected above preliminary action levels. A closure report will be prepared and submitted to the Nevada Division of Environmental Protection for review and approval upon completion of the field activities. Record of Technical Change No. 1 is dated 3/2004.
孙旭峰; Bitsuamlak G T; 胡超
2015-01-01
非高斯脉动风压对围护结构及局部结构构件有较大影响，在设计中应引起足够重视。目前，非高斯风压场的分区研究主要是建立在对实验数据的统计量分析基础上，并非普遍适用，且随机性较强，区内统计特征值亦相差很大，不足以显示不同区域的非高斯程度，故须结合其形成机理加以分析。考虑到在特定风场条件下分离流动及旋涡作用范围具有时均定常的特点，利用稳态数值方法求解的极限流线和粘性流动分离理论的基本结论，结合实验结果分析了典型屋盖结构脉动风压非高斯特性的形成和分布机理。结果表明，极限流线的分布形态与实验统计的偏度及峰态值分布高度相关，可以被很好地应用于风压场非高斯特性的生成及分布机理研究。%The non-Gaussian fluctuating wind pressure greatly affects a building envelope and its local structural elements,it should be paid attention to in the design.Currently,the identification of a non-Gaussian wind pressure field is mainly based on the statistical analysis of the measured data,but its results are not universally suitable.Besides,the method is highly random and the characteristic values of the non-Gaussian area are quite different,so they are not enough to show the non-Gaussian distribution levels in different areas.To overcome this difficulty,the mechanism of non-Gaussian property should also be considered.Here,considering that under conditions of a certain wind field the flow separation and the vortex action sphere were time-averaged stationary,the limiting streamline solved with the steady CFD and the basic conclusions of the viscous flow separation theory were used here,combined with the experimental results,the mechanisms of formation and distribution of the non-Gaussian properties of fluctuating wind pressure for typical roof structures were analyzed.The results showed that the distribution pattern of the
王骑; 廖海黎; 李明水; 马存明
2012-01-01
Taken a streamline box girder for example, the influence of aerodynamic shape on bridge flutter and vertex-induced vibration ( VIV) was studied in detail. Through wind tunnel test of a 1: 50 scale section model, the influences of railing, inspection rail, rostrum, guide wing and inclined web on the flutter and VIV were discussed respectively. The results indicate that railing and inspection rail could weaken the aerodynamic performance of bridge section, while rostrum and guide wing could be used to improve the flutter and VIV performance of bridge. Special indicating is that the increase of flutter wind speed and the vanishing of VIV were all satisfied under the same condition while the slope of inclined web was 15° The brief mechanism of this phenomenon is that the lower inclined web could restrain and delay the formation and shedding of the vertex at the downwind of streamline box girder, thus could remarkably weaken the influence of vertex shedding on VIV and flutter of bridges. But the detailed aerodynamic mechanism will be studied profoundly in future. This development would be beneficial to the wind resistant design of the bridge, and has been applied successfully in the aerodynamic shape design of several long-span bridges in China.%以某流线型钢箱梁断面为例,详细研究了主梁气动外形变化对桥梁颤振和涡振性能的影响.基于1∶50节段模型风洞试验,分别研究了箱梁的栏杆、检修车轨道、风嘴、导流板,以及斜腹板对桥梁颤振及涡振性能的影响.研究表明,栏杆和检修车轨道将弱化桥梁断面的气动性能,而风嘴和导流板则对桥梁的颤振和涡振性能有利.值得提出的是,在其他气动外形保持不变,而斜腹板倾角变为15°时,桥梁的颤振性能不仅获得了较大提升,且涡振现象还可得到消除.此现象的初步机理为:较小的斜腹板倾角可阻碍和廷后流线型箱梁下风侧漩涡的形成和脱落,从而显著削弱漩涡脱
Colvin Christopher J
2011-08-01
Full Text Available Abstract Background Task shifting and the integration of human immunodeficiency virus (HIV care into primary care services have been identified as possible strategies for improving access to antiretroviral treatment (ART. This paper describes the development and content of an intervention involving these two strategies, as part of the Streamlining Tasks and Roles to Expand Treatment and Care for HIV (STRETCH pragmatic randomised controlled trial. Methods: Developing the intervention The intervention was developed following discussions with senior management, clinicians, and clinic staff. These discussions revealed that the establishment of separate antiretroviral treatment services for HIV had resulted in problems in accessing care due to the large number of patients at ART clinics. The intervention developed therefore combined the shifting from doctors to nurses of prescriptions of antiretrovirals (ARVs for uncomplicated patients and the stepwise integration of HIV care into primary care services. Results: Components of the intervention The intervention consisted of regulatory changes, training, and guidelines to support nurse ART prescription, local management teams, an implementation toolkit, and a flexible, phased introduction. Nurse supervisors were equipped to train intervention clinic nurses in ART prescription using outreach education and an integrated primary care guideline. Management teams were set up and a STRETCH coordinator was appointed to oversee the implementation process. Discussion Three important processes were used in developing and implementing this intervention: active participation of clinic staff and local and provincial management, educational outreach to train nurses in intervention sites, and an external facilitator to support all stages of the intervention rollout. The STRETCH trial is registered with Current Control Trials ISRCTN46836853.
Wickline, Alfred
2005-07-01
This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses closure for the following six corrective action units (CAUs) identified in the ''Federal Facility Agreement and Consent Order'' (1996): (1) CAU 530 - LANL Preshot Mud Pits; (2) CAU 531 - LANL Postshot Mud Pits; (3) CAU 532 - LLNL Preshot Mud Pits; (4) CAU 533 - LLNL Postshot Mud Pits; (5) CAU 534 - Exploratory/Instrumentation Mud Pits; and (6) CAU 535 - Mud Pits/Disposal Areas. Corrective Action Units 530-535 consist of corrective action sites (CASs) located in Areas 1-10, 14, 17, 19, and 20 of the Nevada Test Site (NTS). This plan provides the approach for activities needed to gather the necessary information for closing all the CASs within these CAUs. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of all CASs within CAUs 530-535 using the SAFER process. The Data Quality Objective (DQO) process utilized in this investigation follows the approved risk-based closure strategy outlined in the ''Mud Pit Risk-Based Closure Strategy Report'' (NNSA/NSO, 2004b). The closure strategy was developed based on available information including historical documentation of process knowledge, analytical results from previous sampling activities for contaminants of potential concern at similar mud pits located at the NTS and at off-site locations, future land-use scenarios for each NTS area, and potential exposure scenarios along with the calculated risk for human and ecological receptors.
Ghiorso, M. S.
2014-12-01
Computational thermodynamics (CT) represents a collection of numerical techniques that are used to calculate quantitative results from thermodynamic theory. In the Earth sciences, CT is most often applied to estimate the equilibrium properties of solutions, to calculate phase equilibria from models of the thermodynamic properties of materials, and to approximate irreversible reaction pathways by modeling these as a series of local equilibrium steps. The thermodynamic models that underlie CT calculations relate the energy of a phase to temperature, pressure and composition. These relationships are not intuitive and they are seldom well constrained by experimental data; often, intuition must be applied to generate a robust model that satisfies the expectations of use. As a consequence of this situation, the models and databases the support CT applications in geochemistry and petrology are tedious to maintain as new data and observations arise. What is required to make the process more streamlined and responsive is a computational framework that permits the rapid generation of observable outcomes from the underlying data/model collections, and importantly, the ability to update and re-parameterize the constitutive models through direct manipulation of those outcomes. CT procedures that take models/data to the experiential reference frame of phase equilibria involve function minimization, gradient evaluation, the calculation of implicit lines, curves and surfaces, contour extraction, and other related geometrical measures. All these procedures are the mainstay of image processing analysis. Since the commercial escalation of video game technology, open source image processing libraries have emerged (e.g., VTK) that permit real time manipulation and analysis of images. These tools find immediate application to CT calculations of phase equilibria by permitting rapid calculation and real time feedback between model outcome and the underlying model parameters.
Nakamae, Kazuki; Nishimura, Yuki; Takenaga, Mitsumasa; Nakade, Shota; Sakamoto, Naoaki; Ide, Hiroshi; Sakuma, Tetsushi; Yamamoto, Takashi
2017-05-04
The emerging genome editing technology has enabled the creation of gene knock-in cells easily, efficiently, and rapidly, which has dramatically accelerated research in the field of mammalian functional genomics, including in humans. We recently developed a microhomology-mediated end-joining-based gene knock-in method, termed the PITCh system, and presented various examples of its application. Since the PITCh system only requires very short microhomologies (up to 40 bp) and single-guide RNA target sites on the donor vector, the targeting construct can be rapidly prepared compared with the conventional targeting vector for homologous recombination-based knock-in. Here, we established a streamlined pipeline to design and perform PITCh knock-in to further expand the availability of this method by creating web-based design software, PITCh designer ( http://www.mls.sci.hiroshima-u.ac.jp/smg/PITChdesigner/index.html ), as well as presenting an experimental example of versatile gene cassette knock-in. PITCh designer can automatically design not only the appropriate microhomologies but also the primers to construct locus-specific donor vectors for PITCh knock-in. By using our newly established pipeline, a reporter cell line for monitoring endogenous gene expression, and transgenesis (TG) or knock-in/knockout (KIKO) cell line can be produced systematically. Using these new variations of PITCh, an exogenous promoter-driven gene cassette expressing fluorescent protein gene and drug resistance gene can be integrated into a safe harbor or a specific gene locus to create transgenic reporter cells (PITCh-TG) or knockout cells with reporter knock-in (PITCh-KIKO), respectively.
牛占文; 郭梦真; 杨福东; 路振中
2016-01-01
选取以工程机械行业极具代表性的某发动机制造企业生产线为案例，进行作业系统优化和排产设计研究。针对生产线作业系统设计不合理的现状，按照产品原则进行生产线功能重组，实现发动机“整流化”生产；针对辅助人员冗余的情况，利用标准工时测定的方法，进行辅助人员定编，使其得到合理配置，并减少了30％的辅助人员。在此基础上，以生产线加工能力为指导进行排产方法设计，全面实现了生产资源的优化配置。%Take a production line of engine manufacturing enterprise which is a high representative of con-struction machinery industry as example to conduct the operating system optimization and production scheduling design research.Targeting at the current situation of unreasonable production line operating sys-tem design,conduct production line functional reorganization acco rding to the product principle and a-chieve the streamlining production of engine;targeting at the situation of auxiliary personnel redundancy, conduct the personnel allocation of auxiliary personnel by the mean of standard working hours determina-tion and make them has reasonable allocation which reduce 30% auxiliary personnel;on that basis,conduct the production scheduling method design taking the production line processing capability as the guidance, completely achieve the optimization arrangement of production resource.
Streamlining Policy Creation in Policy Frameworks
M.A. Hills (Mark); N. Martí-Oliet; M. Palomino
2012-01-01
textabstract{\\it Policy frameworks} provide a technique for improving reuse in program analysis: the same language frontend, and a core analysis semantics, can be shared among multiple analysis policies for the same language, while analysis domains (such as units of measurement) can be shared among
Streamlining Field Data Collection With Mobile Apps
Camp, Reid J.; Wheaton, Joseph M.
2014-12-01
Fieldwork is a major component of nearly every geoscience discipline. Over the past 3 decades, scientists have amassed an array of specialized instrumentation and equipment to help them measure and monitor a staggering assortment of geophysical phenomena.
76 FR 75825 - Streamlining Inherited Regulations
2011-12-05
... for the marketplace that the market will not generate on its own. For example, before adoption of the... frequently used; fail to reflect technologies that are now in use; or inhibit the use of existing or emerging... ethnicity. 12 CFR 202.913(a). Regulators can use these data to monitor compliance with fair...
Seven Ways to Streamline Student Services
Fredette, Michelle
2011-01-01
To meet the expectations of today's tech-savvy students, colleges and universities are looking for ways to speed up their processes and provide better services for their No. 1 customer. They have turned to technology to simplify processes, reduce costs, and meet the high expectations of a technically literate student body. In this article, the…
Streamlining HIV Testing for HIV Preexposure Prophylaxis
Guanira, Juan V.; Leigler, Teri; Kallas, Esper; Schechter, Mauro; Sharma, Usha; Glidden, David; Grant, Robert M.
2014-01-01
HIV-testing algorithms for preexposure prophylaxis (PrEP) should be optimized to minimize the risk of drug resistance, the time off PrEP required to evaluate false-positive screening results, and costs and to expedite the start of therapy for those confirmed to be infected. HIV rapid tests (RTs) for anti-HIV antibodies provide results in less than 1 h and can be conducted by nonlicensed staff at the point of care. In many regions, Western blot (WB) testing is required to confirm reactive RT r...
Streamlining geospatial metadata in the Semantic Web
Fugazza, Cristiano; Pepe, Monica; Oggioni, Alessandro; Tagliolato, Paolo; Carrara, Paola
2016-04-01
In the geospatial realm, data annotation and discovery rely on a number of ad-hoc formats and protocols. These have been created to enable domain-specific use cases generalized search is not feasible for. Metadata are at the heart of the discovery process and nevertheless they are often neglected or encoded in formats that either are not aimed at efficient retrieval of resources or are plainly outdated. Particularly, the quantum leap represented by the Linked Open Data (LOD) movement did not induce so far a consistent, interlinked baseline in the geospatial domain. In a nutshell, datasets, scientific literature related to them, and ultimately the researchers behind these products are only loosely connected; the corresponding metadata intelligible only to humans, duplicated on different systems, seldom consistently. Instead, our workflow for metadata management envisages i) editing via customizable web- based forms, ii) encoding of records in any XML application profile, iii) translation into RDF (involving the semantic lift of metadata records), and finally iv) storage of the metadata as RDF and back-translation into the original XML format with added semantics-aware features. Phase iii) hinges on relating resource metadata to RDF data structures that represent keywords from code lists and controlled vocabularies, toponyms, researchers, institutes, and virtually any description one can retrieve (or directly publish) in the LOD Cloud. In the context of a distributed Spatial Data Infrastructure (SDI) built on free and open-source software, we detail phases iii) and iv) of our workflow for the semantics-aware management of geospatial metadata.
Streamlining Site Cleanup in New York City
This joint effort, supported by the New York State Department of Environmental Conservation (NYS DEC), advances the environmental cleanup goals of PlaNYC 2030, the city's comprehensive sustainability plan.
Streamlining the accounts payable function with EDI.
Huntley, G; Shride, T; McLure, M L; Moynihan, J J
1997-01-01
Kaiser Permanente of Southern California is expanding its use of EDI as a way to enhance the efficiency of its procurement effort and reduce administrative costs. Based on the results of surveys of key suppliers, Kaiser executives identified four EDI-based process improvements: 1) using the X12 832 standard to reconcile contracting data, which can eliminate up to 33 percent of mismatches among purchase orders, invoices, and receiving documents; 2) using procurement cards for many purchases, which can eliminate 20 percent of all invoices and related check payments; 3) using the X12 810 standard to obtain electronic invoices from Kaiser's largest suppliers; and 4) implementing the X12 820 standard, which lowers both supplier and claims payment costs.
Streamlining Education System Through Waqf Enlargement
Imam Bahroni
2016-06-01
Full Text Available This paper is aimed at discussing the development of education systembased on the Waqf Empowerment. It is an experience of Gontor ModernIntegrated Islamic Institution to maintain its existence through the activitiesof Waqf Enlargement. The spirit of self-reliance which has been implementedby Gontor through various economic enterprise activities inside the campus isthe total processes of educational activities, carried out by students andteachers themselves. They act as the subjects and objects of the education atthe same time. They teach themselves through various activities, creativitiesand social interaction for their character and personality building. Thislearning process is purposely undertaken in Gontor, because the basicprinciple of this system is to actualize the community orientation throughwhich the students in the campus guided and prepared to have a spirit ofself reliance. So when they back to the society to undertake the real life theyconfidently take their role to develop their society for the sake of Allah andunity of muslim ummah.
How streamlining telecommunications can cut IT expense.
McIntyre, Greg
2016-02-01
Hospitals and health systems can save IT expenses by implementing more efficient processes in accordance with the principles of effective telecommunications expense management. This approach involves three primary steps: Inventory of existing infrastructure. Charge verification. Optimization of rates and design for continual improvement.
Streamlining Cooperative Office Education Student Selection
Herwick, Mary Jo; Regennitter, John F.
1977-01-01
When applicants for the cooperative office education program exceed space and funds, the coordinator must have a sound basis for selecting students. This article presents both fixed and variable selection criteria to enable the coordinator to evaluate applicants with minimum subjectivity. (MF)
Gust loading on streamlined bridge decks
Larose, Guy; Mann, Jakob
1998-01-01
The current analytical description of the buffeting action of wind on long-span bridges is based on the strip assumption. However, recent experiments on closed-box girder bridge decks have shown that this assumption is not valid and is the source of an important part of the error margin...... of the analytical prediction methods. In this paper, an analytical model that departs from the strip assumption is used to describe the gust loading on a thin airfoil. A parallel is drawn between the analytical model and direct measurements of gust loading on motionless closed-box girder bridge decks. Empirical...
Mobile technology: streamlining practice and improving care
Blake, Holly
2013-01-01
The use of mobile phones in care delivery has the potential to improve the way in which care is delivered. When implemented effectively, mobile technologies can empower patients and enhance communication between patients and their health-care providers. When barriers are recognised and addressed, mobile technologies can change working lives, facilitating rapid access to information and supporting efficiency in practice.
Streamlining Compliance Validation Through Automation Processes
2014-03-01
up to 16 data storage registers. By contrast, the Raspberry Pi is a credit card sized computer that is sold for $35 and comes “stock” with 512MB... Raspberry Pi Foundation. Raspberry Pi FAQs. [Online]. Available: http://www.raspberrypi.org/faqs [5] R. Meulen and C. Pettey. (2008, June). Gartner
A streamlined approach for pipeline integrity management
Porter, T.R. [Tuboscope Pipeline Services, Houston, TX (United States); Marr, J.E. [Marr and Associates, A Tuboscope Company, Calgary, AB (Canada)
2004-07-01
While regulations call for safe and reliable operation of pipelines, business calls for economic return and reduced liability. This paper presented a system that provides rapid, comprehensive and economic improvements for pipeline integrity decision support. The first phase of a pipeline integrity management plan (IMP) involves the identification of integrity threats to the pipeline. This may involve 22 root causes as defined by the Pipeline Research Council International (PRCI), grouped into 9 categories of related failure types, further grouped into time related defect types. Time dependent defects include external corrosion, internal corrosion and stress corrosion cracking. Stable defects include manufacturing related or welding defects, while time independent defects include mechanical damage, incorrect operations and outside forces. In designing an IMP, high consequence areas (HCAs) must be defined along with the integrity threats that could affect the pipeline. A baseline risk assessment is then performed using data from the integrity threat models to identify risks areas, individual lines, pipe segments or joints. Integrity management decisions are made based on the outcome of initial assessments, resulting in integrity assessment tools such as in line inspection (ILI) technologies, direct assessment (DA), and hydrostatic testing. Pipeline engineers benefit from having ILI, DA and other data integrated and interacting with geographic information system (GIS) data. This paper presented the LinaView PRO{sup TM} IMP tool developed by Tuboscope that enhances dig smart excavation decision making; remediation and mitigation planning; responding to one-call emergency response; implementation of government regulations; HCA identification; integration of a wide variety of data; comprehensive dynamic segmentation; and, data validation in support of risk assessment. The objective of an IMP is the safe and reliable delivery system for oil and gas product to markets. 9 refs., 6 figs.
Streamlining DOD Acquisitions: Balancing Schedule with Complexity
2006-09-01
spurring rapid aircraft development and production. After a relatively stagnant period in the interwar years, the mid- 1930s witnessed a burst of...1986), xiv. 105. Jacob Neufeld. Research and Development in the United States Air Force, 23. and http://www.boeing.com/history/boeing/ b17 .html 106
Streamlining the path from physics to medicine
2013-01-01
We all know them: the well-established cases of knowledge transfer from physics to medicine in which CERN has played an important role. From technology for PET scanners to dedicated accelerator designs for cancer therapy, we have contributed a lot over the years. But until recently, the pathway has been a little ad hoc, depending largely on enthusiastic individuals. That’s about to change. CERN’s commitment to formalising the transfer of knowledge to the field of medicine has been growing over recent years. Notable successes are the establishment of a new conference series, ICTR-PHE, that brings together medical practitioners and members of the physics community, and the establishment of cancer therapy centres like CNAO in Italy and MedAustron in Austria, built on CERN accelerator technology. These are important, but there’s still more that we can and should do. To this end, we’ve created a new Office for CERN Medical Applications, whose first head w...
Streamlining Policy Creation in Policy Frameworks
Hills, M.A.; Martí-Oliet, N.; Palomino, M.
2012-01-01
{\\it Policy frameworks} provide a technique for improving reuse in program analysis: the same language frontend, and a core analysis semantics, can be shared among multiple analysis policies for the same language, while analysis domains (such as units of measurement) can be shared among frameworks f
Morrison, Evan; Sullivan, Emma; Dam, Hoa Khanh
2016-01-01
Background Standardizing the background diet of participants during a dietary randomized controlled trial is vital to trial outcomes. For this process, dietary modeling based on food groups and their target servings is employed via a dietary prescription before an intervention, often using a manual process. Partial automation has employed the use of linear programming. Validity of the modeling approach is critical to allow trial outcomes to be translated to practice. Objective This paper describes the first-stage development of a tool to automatically perform dietary modeling using food group and macronutrient requirements as a test case. The Dietary Modeling Tool (DMT) was then compared with existing approaches to dietary modeling (manual and partially automated), which were previously available to dietitians working within a dietary intervention trial. Methods Constraint optimization techniques were implemented to determine whether nonlinear constraints are best suited to the development of the automated dietary modeling tool using food composition and food consumption data. Dietary models were produced and compared with a manual Microsoft Excel calculator, a partially automated Excel Solver approach, and the automated DMT that was developed. Results The web-based DMT was produced using nonlinear constraint optimization, incorporating estimated energy requirement calculations, nutrition guidance systems, and the flexibility to amend food group targets for individuals. Percentage differences between modeling tools revealed similar results for the macronutrients. Polyunsaturated fatty acids and monounsaturated fatty acids showed greater variation between tools (practically equating to a 2-teaspoon difference), although it was not considered clinically significant when the whole diet, as opposed to targeted nutrients or energy requirements, were being addressed. Conclusions Automated modeling tools can streamline the modeling process for dietary intervention trials
徐建设; 陈辉; 傅卫军; 唐靖
2010-01-01
Objective To compare the performance of the streamlined pharynx airway liner (SLIPA~(TM)) with the conventional laryngeal mask airway(LMA) for airway management in minor surgery under general anesthesia. Methods Sixty fasted adult patients with ASA status Ⅰ～Ⅱ were randomly designed to establish SLIPA~(TM) airway (SLIPA~(TM) group) or LMA airway(LMA group) for airway management during anesthesia. Article airway handling, pharynx sealing, ventilation maintenance and adverse reactions with SLIPA~(TM) group and LMA group were assessed. Results SLIPA~(TM) had comparable total rate of successful insertion and airway placement difficulty to LMA(P>0.05). Maximum seal pressure was (22±5) cm H_20 and (24±6) cm H_2O in SLIPA~(TM) group and LMA group (P>0.05), respectively. A leak was noticed in 20% and 16.7% of patiemts in LMA group when patients' lungs were ventilated using intermittent positive pressure ventilation mode after airway mask placment and during surgery, and 3.3% and 0 in SLIPA~(TM) group (P0.05).通气道插入后SLIPA~(TM)组1例患者(3.3%)、LMA组6例患者(20%)需进一步调整位置方可行间歇正压通气;术中lJMA组5例患者(16.7%)需重新调整方可维持间歇正压通气,SLIPA~(TM)组均顺利完成手术全程间歇正压通气(P<0.05).2种喉罩通气道喉损伤的发生率差异无统计学意义.结论 SLIPA~(TM)喉罩的临床性能与LMA相似,是一种可替代LMA的通气道.SLIPA~(TM)喉罩操作简便,对咽喉损伤较小,维持间歇正压通气较LMA更为稳定.
Kazemi A.
2013-05-01
Full Text Available It is becoming more and more common to use assisted history matching methods to find different combinations of reservoir simulation models that agree with production data. Models with a large number of cells contain millions of unknown parameters and selecting the correct property values can be difficult. In practice, not all are important but finding which parts of the reservoir require updating is a challenge. In this work, we investigate methods of history matching by focusing on sub-sets of the full array model parameters and we use streamlines to help us choose where the model requires change. We identify localities in the reservoir that affect particular wells and we update reservoir properties (net:gross and permeability within. We control changes using the pilot point method combined with a Neighbourhood Algorithm. We apply these approaches to the Nelson field (North Sea, UK where uncertainty of the shale distribution controls predictions. The field is divided into localities based on the performance of the worst well predictions. We history match to improve production rates. The localities that require change are sufficiently separate that we can modify them one at a time. We also compare our result with a more ad hoc approach where the whole area around the well is modified. We find that, for the wells of interest, the streamline guided approach gives a 70% improvement in the history match from our starting model and around 40% reduction of misfit in prediction. This improvement is twice that of modifying the properties all around the well. L’utilisation de méthodes de calage d’historique assisté est de plus en plus fréquente pour déterminer différentes combinaisons de modèles de réservoir reproduisant les données de production. Les modèles comprenant un grand nombre de cellules contiennent des millions de paramètres inconnus, et leur attribuer des valeurs appropriées peut s’avérer difficile. En pratique, tous les
阮嘉赓; 张农; Paul Walker; 方煜宏
2015-01-01
电动汽车当前阶段的首要设计目标是获得与传统汽车相近的驾驶性能和续驶里程，且制造成本要控制在合理范围。为实现这一目标，提出了一种精简型无级变速机构，并对采用了固定速比减速器和精简型无级变速器的两种纯电动汽车的驾驶性能和能源利用率进行对比。结果表明，相比于固定速比减速器，精简型无级变速器提高了电机的工作效率且减少了电能消耗，同时整车制造成本和使用费用也有所降低。%The primary objective of electric vehicle for the present time is to attain the driveability and driving range similar to that of conventional vehicle, and control the manufacturing cost in a reasonable range. For this end, we put forward a streamlined continuously variable transmission (CVT) mechanism, and compare the driveability and energy utilization rate of two pure electric vehicles equipped with fixed speed ratio reducer and streamlined CVT respectively. The results show that compared with the fixed speed ratio reducer, the streamlined CVT increases operating efficiency of motor, reduces power consumption, meanwhile cut down vehicle manufacturing cost and TCO.
张庆兵; 韩苗华; 周懿; 封丽丽; 刘佳; 刘毅
2014-01-01
Objective:To verify the factors associated with gas leakage in applying of streamlined liner of the pharyngeal airway ( SLIPA) with classic la-ryngeal mask airway (LMA) to mechanically ventilated patients in general anesthesia.Methods:260 patients undergone minor surgery with general anes-thesia were included and recorded regarding the gender, ages, body mass index, Mallampati classification, neck circumference, thyromental distance (TMD),mandibular length,width of mouth opening and status of teeth before anesthesia.Selection of the LMA size was complied to the width of thyroid cartilage of patients,and determination of LMA leakage was based on the operator′s experience and tidal volume monitoring.χ2 test was used to analyze the difference concerning the parameters described previously between the leakage group and the non-leakage group.Results:SLIPA LMAs were successfully applied in 254 patients,whereas LMA leakage was found in 17 cases.Higher incidence of the gas leakage was seen patients with shorter TMD (35% vs. 5%) and without teeth (29% vs.3% )when the two groups were compared (P<0.05).Conclusion:SLIPA LMA can be safely used in mechanically ventilated patients under general anesthesia,yet higher incidences of gas leakage may be involved in those with short TMD or without teeth.%目的：筛选全麻机械通气使用SLIPA喉罩时发生漏气的相关因素。方法：选取短小全麻手术260例，记录患者性别、年龄、体质量指数、Mallampati分级、颈围、甲颏距、下颌骨水平长度、张口度以及牙齿情况。根据甲状软骨宽度选取合适型号的喉罩。操作者根据临床经验和潮气量监测判断喉罩是否漏气。采用卡方检验比较喉罩漏气和未漏气两组患者间各项指标的差异。结果：260例患者成功置入SLIPA喉罩，其中17例出现喉罩漏气。与喉罩未漏气患者相比，喉罩漏气患者短颏甲距（35％vs．5％）和无牙（29％vs．3
陈作舟; 薛成海; 朱晟; 周丰丰; XUEFENG BRUCE LING; 刘国平; 陈良标
2005-01-01
high annotation specificity of 99.1% was achieved for a test dataset when the program was run in the "intersection" mode, which intersects the BLAST and InterProScan results,outperforming the specificity (81.1%) obtained from the InterProScan only. Statistical tools are also provided to compare GO distributions between different inputs, so that GO distributions of different sets of batch sequences can be compared,and differentially represented GO terms can be easily displayed. High specificity, speed and flexibility make GoPipe an ideal tool for streamlined GO annotation for batch sequences. The package is freely available at http://gopipe.fishgenome.org/or by contacting the authors.
Roberts, Nathan V. [Argonne National Lab. (ANL), Argonne, IL (United States). Argonne Leadership Computing Facility
2016-09-28
Camellia began as an effort to simplify implementation of efficient solvers for the discontinuous Petrov-Galerkin (DPG) finite element methodology of Demkowicz and Gopalakrishnan. Since then, the feature set has expanded, to allow implementation of traditional continuous Galerkin methods, as well as discontinuous Galerkin (DG) methods, hybridizable DG (HDG) methods, first-order-system least squares (FOSLS), and the primal DPG method. This manual serves as an introduction to using Camellia. We begin, in Section 1.1, by describing some of the core features of Camellia. In Section 1.2 we provide an outline of the manual as a whole.
Tahavori, Maryamsadat; Shaker, Hamid Reza
A method for model reduction of dynamical systems with the second order structure is proposed in this paper. The proposed technique preserves the second order structure of the system, and also preserves the stability of the original systems. The method uses the controllability and observability...... gramians within the time interval to build the appropriate Petrov-Galerkin projection for dynamical systems within the time interval of interest. The bound on approximation error is also derived. The numerical results are compared with the counterparts from other techniques. The results confirm...
Finite element method for extended KdV equations
Karczewska, Anna; Szczeciński, Maciej; Boguniewicz, Bartosz
2016-01-01
The finite element method (FEM) is applied to obtain numerical solutions to a recently derived nonlinear equation for the shallow water wave problem. A weak formulation and the Petrov-Galerkin method are used. It is shown that the FEM gives a reasonable description of the wave dynamics of soliton waves governed by extended KdV equations. Some new results for several cases of bottom shapes are presented. The numerical scheme presented here is suitable for taking into account stochastic effects, which will be discussed in a subsequent paper.
Burago, N. G.; Nikitin, I. S.; Yakushev, V. L.
2016-06-01
Techniques that improve the accuracy of numerical solutions and reduce their computational costs are discussed as applied to continuum mechanics problems with complex time-varying geometry. The approach combines shock-capturing computations with the following methods: (1) overlapping meshes for specifying complex geometry; (2) elastic arbitrarily moving adaptive meshes for minimizing the approximation errors near shock waves, boundary layers, contact discontinuities, and moving boundaries; (3) matrix-free implementation of efficient iterative and explicit-implicit finite element schemes; (4) balancing viscosity (version of the stabilized Petrov-Galerkin method); (5) exponential adjustment of physical viscosity coefficients; and (6) stepwise correction of solutions for providing their monotonicity and conservativeness.
Isaev, S. A.; Baranov, P. A.; Sudakov, A. G.; Popov, I. A.
2016-08-01
A modification of the popular model of shear stress transport aimed at calculating the separation flow of an incompressible viscous liquid is justified. The modification eliminates the nonphysical pumping of the vortex viscosity in the cores of large-scale vortices. It has been verified with regard to the influence of the streamline curvature on the vortex viscosity by introducing a reciprocal linear function of the turbulent Richardson number with the Isaev-Kharchenko-Usachov constant equal to 0.02.Verification is based on solving the test problem an axisymmetric steady flow about a disk-cylinder tandem with an optimally configured nose, which has an ultralow profile drag for a Reynolds number of 5 × 105. It has been shown that the Menter combined boundary conditions are valid if y + y of the wall does not exceed two.
Application of the FIDAP code to the 8:1 thermal cavity problem
Gresho, P. M.; Sutton, S. B.
2002-11-01
We present results using FIDAP on 3 meshes with 3 different elements (Q1Q0, Q2P-1, Q2Q-1) employed on each. Whereas the bulk of the results were obtained via the classical Galerkin finite element method (GFEM) and the trapezoidal (TR) time integrator, we also tested several alternative options: flux-conservative formulation, energy-conservative formulation, streamline upwinding, mass lumping, backward Euler time stepping, and one additional element (Q2Q1). The most accurate of these options was the Q2Q-1 element in the advective formulation, no upwinding, trapezoidal time integration, and consistent mass; i.e. straight GFEM.
Doppler lidar mounted on a wind turbine nacelle – UPWIND deliverable D6.7.1
Angelou, Nikolas; Mann, Jakob; Courtney, Michael
was the investigation of the turbulence attenuation induced in the lidar measurements. In this report are presented results from data analysis over a 21-hour period (2009-05-05 12:00 – 2009-05-06 09:00). During this period the wind turbine was not operating and the line-of-sight of the lidar was aligned with the wind...... measurements, was estimated by means of spectral analysis. An attempt to increase the resolution of the wind speed measurements of a cw lidar was performed, through the deconvolution of the lidar signal. A theoretical model of such a procedure is presented in this report. A simulation has validated...
Doppler lidar mounted on a wind turbine nacelle - UPWIND deliverable D6.7.1
Angelou, N.; Mann, J.; Courtney, M.; Sjoeholm, M.
2010-12-15
A ZephIR prototype wind lidar manufactured by QinetiQ was mounted on the nacelle of a Vestas V27 wind turbine and measurements of the incoming wind flow towards the rotor of the wind turbine were acquired for approximately 3 months (April - June 2009). The objective of this experiment was the investigation of the turbulence attenuation induced in the lidar measurements. In this report are presented results from data analysis over a 21-hour period (2009-05-05 12:00 - 2009-05-06 09:00). During this period the wind turbine was not operating and the line-of-sight of the lidar was aligned with the wind direction. The analysis included a correlation study between the ZephIR lidar and a METEK sonic anemometer. The correlation analysis was performed using both 10 minutes and 10 Hz wind speed values. The spectral transfer function which describes the turbulence attenuation, which is induced in the lidar measurements, was estimated by means of spectral analysis. An attempt to increase the resolution of the wind speed measurements of a cw lidar was performed, through the deconvolution of the lidar signal. A theoretical model of such a procedure is presented in this report. A simulation has validated the capability of the algorithm to deconvolve and consequently increase the resolution of the lidar system. However the proposed method was not efficient when applied to real lidar wind speed measurements, probably due to the effect, that the wind direction fluctuations along the lidar's line-of-sight have, on the lidar measurements. (Author)
2014-01-07
a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. Utah State University 1415 Old Main Hill - Room 64 Logan ...Folkner,† Aaron Katz,‡ Department of Mechanical and Aerospace Engineering, Utah State University, Logan , UT 84322 Venke Sankaran§ Rocket Propulsion
Doppler lidar mounted on a wind turbine nacelle – UPWIND deliverable D6.7.1
Angelou, Nikolas; Mann, Jakob; Courtney, Michael; Sjöholm, Mikael
2010-01-01
A ZephIR prototype wind lidar manufactured by QinetiQ was mounted on the nacelle of a Vestas V27 wind turbine and measurements of the incoming wind flow towards the rotor of the wind turbine were acquired for approximately 3 months (April - June 2009). The objective of this experiment was the investigation of the turbulence attenuation induced in the lidar measurements. In this report are presented results from data analysis over a 21-hour period (2009-05-05 12:00 – 2009-05-06 09:00). During ...
UPWIND Metrology, Deliverable D 1A2.1, List of measurement Parameters
Hansen, Kurt Schaldemose
as convincing field tests have not confirmed the actual improvement, the industry will not invest much to change the turbine design. This is an example that clarifies why the development of wind energy is hindered by metrology problems (measurement problems). Other examples are in the fields of: - Warranty...... activity. The problem is especially relevant for the following areas: Production related - Power performance testing especially in wind farms - Testing of turbine improvements in the order of several percent - Testing of aerodynamic codes - Testing of turbine response to effects such as turbulence...... and shear Load related - Mechanical load measurements in farms aimed at verification of aero elastic codes. (blade root moments, yaw moments, tower foot moments etc.) Wind related - Measurement of wake effects and wind resources inside wind farms - Measurements of inter farm effects (regarding velocity...
Upwind scheme for acoustic disturbances generated by low-speed flows
Ekaterinaris, J.A.
1997-01-01
, compressible how equations, A numerical method for the solution of the equations governing the acoustic field is presented. The primitive variable form of the governing equations is used for the numerical solution. Time integration is performed with a fourth-order, Runge-Kutta method, Discretization...
Sidilkover, David
1994-01-01
We present a new approach towards the construction of a genuinely multidimensional high-resolution scheme for computing steady-state solutions of the Euler equations of gas dynamics. The unique advantage of this approach is that the Gauss-Seidel relaxation is stable when applied directly to the high-resolution discrete equations, thus allowing us to construct a very efficient and simple multigrid steady-state solver. This is the only high-resolution scheme known to us that has this property. The two-dimensional scheme is presented in detail. It is formulated on triangular (structured and unstructured) meshes and can be interpreted as a genuinely two-dimensional extension of the Roe scheme. The quality of the solutions obtained using this scheme and the performance of the multigrid algorithm are illustrated by the numerical experiments. Construction of the three dimensional scheme is outlined briefly as well.
Accuracy of an unstructured-grid upwind-Euler algorithm for the ONERA M6 wing
Batina, John T.
1991-01-01
Improved algorithms for the solution of the three-dimensional, time-dependent Euler equations are presented for aerodynamic analysis involving unstructured dynamic meshes. The improvements have been developed recently to the spatial and temporal discretizations used by unstructured-grid flow solvers. The spatial discretization involves a flux-split approach that is naturally dissipative and captures shock waves sharply with at most one grid point within the shock structure. The temporal discretization involves either an explicit time-integration scheme using a multistage Runge-Kutta procedure or an implicit time-integration scheme using a Gauss-Seidel relaxation procedure, which is computationally efficient for either steady or unsteady flow problems. With the implicit Gauss-Seidel procedure, very large time steps may be used for rapid convergence to steady state, and the step size for unsteady cases may be selected for temporal accuracy rather than for numerical stability. Steady flow results are presented for both the NACA 0012 airfoil and the Office National d'Etudes et de Recherches Aerospatiales M6 wing to demonstrate applications of the new Euler solvers. The paper presents a description of the Euler solvers along with results and comparisons that assess the capability.
UpWind D1. Uncertainties in wind assessment with LIDAR
Lindeloew-Marsden, P.
2009-01-15
In this report sources influencing wind assessments with lidars are listed and discussed. Comparisons with mast mounted cup anemometers are presented and the magnitudes of the errors from the listed error sources are estimated. Finally an attempt to define uncertainty windows for the current state of the two commercial wind sensing lidars is presented. The results in this report give important feedback on system improvements to manufacturers and an estimation of the current ability for wind farm developers which are potential users. (author)
Predicting MBA Student Success and Streamlining the Admissions Process
Pratt, William R.
2015-01-01
Within this study the author examines factors commonly employed as master of business administration applicant evaluation criteria to see if these criteria are important in determining an applicant's potential for success. The findings indicate that the Graduate Management Admissions Test (GMAT) is not a significant predictor of student success…
Streamlining resummed QCD calculations using Monte Carlo integration
Farhi, David; Freytsis, Marat; Schwartz, Matthew D
2015-01-01
Some of the most arduous and error-prone aspects of precision resummed calculations are related to the partonic hard process, having nothing to do with the resummation. In particular, interfacing to parton-distribution functions, combining various channels, and performing the phase space integration can be limiting factors in completing calculations. Conveniently, however, most of these tasks are already automated in many Monte Carlo programs, such as MadGraph, Alpgen or Sherpa. In this paper, we show how such programs can be used to produce distributions of partonic kinematics with associated color structures representing the hard factor in a resummed distribution. These distributions can then be used to weight convolutions of jet, soft and beam functions producing a complete resummed calculation. In fact, only around 1000 unweighted events are necessary to produce precise distributions. A number of examples and checks are provided, including $e^+e^-$ two- and four-jet event shapes, $n$-jettiness and jet-mas...
Recording, editing, archiving, and distributing radiology lectures: a streamlined approach.
Purcell, Derk D; Hess, Christopher P; Durack, Jeremy C; Breiman, Richard S
2007-01-01
Recent advances in digital recording technology have simplified the recording of audio, video, and image information from didactic radiology conferences. Recording lectures in a suitable digital format has several advantages, including the ability to edit lecture content, combine lectures conducted at different times and places, store media digitally, and broadcast conferences electronically over the Internet. An inexpensive, commercially available conversion device was developed that allows straightforward capture and compression of multimedia audiovisual information, thus facilitating the use of this information by the conference presenter as well as the end user. A converter is connected to a personal computer (PC) by means of standard connections, and editing and compression of digital media are performed on the PC prior to their distribution and archiving. The result is a high-quality, highly compressed file that can be played back from any PC and from many portable video devices. This approach represents a simple and cost-effective means of creating and maintaining a library of didactic lectures for students and trainees in radiology. RSNA, 2007
Computer program /TURBLE/ for calculating velocities and streamlines in turbomachines
Katsanis, T.; Mcnally, W. D.
1971-01-01
Program is used in design of turbomachinery blade rows, where fluid velocities in blade to blade passage must be obtained. TURBLE requires input data on blade geometry, meridional stream-channel geometry, total flow conditions, weight flow, and inlet and outlet flow angles.
A framework for streamlining research workflow in neuroscience and psychology
Jonas eKubilius
2014-01-01
Full Text Available Successful accumulation of knowledge is critically dependent on the ability to verify and replicate every part of scientific conduct. However, such principles are difficult to enact when researchers continue to resort on ad hoc workflows and with poorly maintained code base. In this paper I examine the needs of neuroscience and psychology community, and introduce psychopy_ext, a unifying framework that seamlessly integrates popular experiment building, analysis and manuscript preparation tools by choosing reasonable defaults and implementing relatively rigid patterns of workflow. This structure allows for automation of multiple tasks, such as generated user interfaces, unit testing, control analyses of stimuli, single-command access to descriptive statistics, and publication quality plotting. Taken together, psychopy_ext opens an exciting possibility for faster, more robust code development and collaboration for researchers.
Alkalizing Reactions Streamline Cellular Metabolism in Acidogenic Microorganisms
Arioli, Stefania; Ragg, Enzio; Scaglioni, Leonardo; Fessas, Dimitrios; Signorelli, Marco; Karp, Matti; Daffonchio, Daniele; De Noni, Ivano; Mulas, Laura; Oggioni, Marco; Guglielmetti, Simone; Mora, Diego
2010-01-01
An understanding of the integrated relationships among the principal cellular functions that govern the bioenergetic reactions of an organism is necessary to determine how cells remain viable and optimise their fitness in the environment. Urease is a complex enzyme that catalyzes the hydrolysis of urea to ammonia and carbonic acid. While the induction of urease activity by several microorganisms has been predominantly considered a stress-response that is initiated to generate a nitrogen source in response to a low environmental pH, here we demonstrate a new role of urease in the optimisation of cellular bioenergetics. We show that urea hydrolysis increases the catabolic efficiency of Streptococcus thermophilus, a lactic acid bacterium that is widely used in the industrial manufacture of dairy products. By modulating the intracellular pH and thereby increasing the activity of β-galactosidase, glycolytic enzymes and lactate dehydrogenase, urease increases the overall change in enthalpy generated by the bioenergetic reactions. A cooperative altruistic behaviour of urease-positive microorganisms on the urease-negative microorganisms within the same environment was also observed. The physiological role of a single enzymatic activity demonstrates a novel and unexpected view of the non-transcriptional regulatory mechanisms that govern the bioenergetics of a bacterial cell, highlighting a new role for cytosol-alkalizing biochemical pathways in acidogenic microorganisms. PMID:21152088
Predicting MBA Student Success and Streamlining the Admissions Process
Pratt, William R.
2015-01-01
Within this study the author examines factors commonly employed as master of business administration applicant evaluation criteria to see if these criteria are important in determining an applicant's potential for success. The findings indicate that the Graduate Management Admissions Test (GMAT) is not a significant predictor of student success…
Streamlining the Process of Acquiring Secure Open Architecture Software Systems
2013-10-08
million copies of CS and its descendants ( Makuch , 2011). ^Åèìáëáíáçå=oÉëÉ~êÅÜ=mêçÖê~ã= dê~Çì~íÉ=pÅÜççä=çÑ=_ìëáåÉëë=C=mìÄäáÅ=mçäáÅó - 101 - k~î~ä...Addison-Wesley. Lamsweerde, A. v. (2009). Requirements engineering: From system goals to UML models to software specifications. Wiley. Makuch , E. (2011
DNA extraction for streamlined metagenomics of diverse environmental samples.
Marotz, Clarisse; Amir, Amnon; Humphrey, Greg; Gaffney, James; Gogul, Grant; Knight, Rob
2017-06-01
A major bottleneck for metagenomic sequencing is rapid and efficient DNA extraction. Here, we compare the extraction efficiencies of three magnetic bead-based platforms (KingFisher, epMotion, and Tecan) to a standardized column-based extraction platform across a variety of sample types, including feces, oral, skin, soil, and water. Replicate sample plates were extracted and prepared for 16S rRNA gene amplicon sequencing in parallel to assess extraction bias and DNA quality. The data demonstrate that any effect of extraction method on sequencing results was small compared with the variability across samples; however, the KingFisher platform produced the largest number of high-quality reads in the shortest amount of time. Based on these results, we have identified an extraction pipeline that dramatically reduces sample processing time without sacrificing bacterial taxonomic or abundance information.
76 FR 24339 - Streamlining Service Delivery and Improving Customer Service
2011-05-02
... standards and expectations, including, where appropriate, performance goals for customer service required by...; and (f) identifying ways to use innovative technologies to accomplish the customer service activities... Office of Science and Technology Policy shall assist and support agencies in developing customer service...
Streamlining U.S. Army Military Installation Map (MIM) Production
2010-06-01
Assurance Plans ( QAPs ). Serves as the standardized data structure across all Army training and testing installations. Once populated, this...produced NGA MIMs and supporting documentation. All aspects reflect the layout, fonts, and features which are common to MIMs. Based on SRP QAP (CIP
Darwin core based data streamlining with digimus 2.0
Kakodkar, A.P.; Kerkar, S.S.; Varghese, N.S.; Kavlekar, D.P.; Achuthankutty, C.T.
smaller datasets into a larger information system requires uniformity of data based on a single data standard. In the developing world smaller datasets are maintained by individual researchers or small college and university groups. To standardize data...
Aligning BIM with FM: streamlining the process for future projects
Colleen Kasprzak
2012-12-01
Full Text Available A study performed by the National Institute of Standards and Technology (NIST, USA in 2004 found that owners account for approximately $10.6 billion of the $15.8 billion total inadequate interoperability costs of U.S. capital facility projects in 2002. Because of these inefficiency costs, it becomes vital that information produced during the design and construction phases of a project be transferred into operations with maximum leverage to the end users. However, very few owners have defined these informational needs or developed an integration strategy into existing maintenance management systems. To increase operational efficiency, an organization must first develop an understanding of their operating systems, as well as identify how Building Information Modeling (BIM will add value to their daily tasks. The Pennsylvania State University (PSU has a unique opportunity to diversely implement BIM processes because not only does the University act as an owner, but also as designer and construction manager on the majority of projects. The struggle that PSU faces is one that is unique only to owners with a large, existing, multifaceted building inventory. This paper outlines the current initiative by the Office of Physical Plant (OPP, the asset manager at PSU, to develop an information exchange framework between BIM and FM applications to be used internally. As a result of this research, PSU has been able to define owner operational requirements for future projects and develop a flexible integration framework to support additional BIM tasks and information exchanges.
On Stagnation points and streamline topology in vortex flows
Aref, Hassan; Brøns, Morten
1997-01-01
The problem of locating stagnation points in the flow produced by a system of N interacting point vortices in two dimensions is considered. The general solution, which follows from an 1864 theorem by Siebeck, that the stagnation points are the foci of a certain plane curve of class N-1 that has a...
Linking and Streamlining the Defense Requirements, Acquisition, and Budget Processes
2012-08-01
Mr. William R. Phillips; Dr. Dov S. Zakheim; General Michael P.C. Carns , USAF (Ret); Admiral Vernon E. Clark, USN (Ret); and General Paul J. Kern... Carns , USAF (Ret) General Paul Kern, USA (Ret) Colonel Jack Curran, USA, DBB Military Assistant Task Group Overview 4 Analyzed Past Studies...Mvtlon An aty.ls Phn•- Technology Dev .. opm•nt Phno --- ---Engln .. rln g &. Manl.lfactvrlng Oovolopm.nt Ph •M--- ---:=:.:=::.:.:.==-==· r\\ DEFENSE
Tiers for Fears: Sensible, Streamlined Sharing of Special Collections
Massie, Dennis
2013-01-01
This report presents strategies for providing efficient and affordable interlending of actual physical items from special collections for research purposes, as well as advice on determining if a loan is the most appropriate way to fulfill a particular request. Lending physical items ranks among the most divisive issues in the field of archives and…
Streamlining workflow and automation to accelerate laboratory scale protein production.
Konczal, Jennifer; Gray, Christopher H
2017-03-19
Protein production facilities are often required to produce diverse arrays of proteins for demanding methodologies including crystallography, NMR, ITC and other reagent intensive techniques. It is common for these teams to find themselves a bottleneck in the pipeline of ambitious projects. This pressure to deliver has resulted in the evolution of many novel methods to increase capacity and throughput at all stages in the pipeline for generation of recombinant proteins. This review aims to describe current and emerging options to accelerate the success of protein production in Escherichia coli. We emphasize technologies that have been evaluated and implemented in our laboratory, including innovative molecular biology and expression vectors, small-scale expression screening strategies and the automation of parallel and multidimensional chromatography.
Streamlining Data for Cross-Platform Web Delivery
Watkins, Sean; Battles, Jason; Vacek, Rachel
2013-01-01
Smartphone users expect the presentation of Web sites on their mobile browsers to look and feel like native applications. With the pressure on library Web developers to produce app-like mobile sites, there is often a rush to get a site up without considering the importance of reusing or even restructuring the data driving the Web sites. An…
ADVANCING TECHNOLOGY AND METHODOLOGY TO STREAMLINE ENVIRONMENTAL COMPLIANCE
Ben Grunewald; Paul Jehn
2002-11-15
By early 2000, fifteen oil and gas State Agencies were using RBDMS or a RBDMS utility to handle a significant amount or all of their data management needs. There are three additional State slated to begin implementation this year. There are an additional twelve State agencies that are not utilizing this technology that have proven to be very useful for so many other States. This project will allow for the base RBDMS install in all State oil and gas agency that desire it.
Spherical Coordinate Systems for Streamlining Suited Mobility Analysis
Benson, Elizabeth; Cowley, Matthew S.; Harvill. Lauren; Rajulu, Sudhakar
2014-01-01
When describing human motion, biomechanists generally report joint angles in terms of Euler angle rotation sequences. However, there are known limitations in using this method to describe complex motions such as the shoulder joint during a baseball pitch. Euler angle notation uses a series of three rotations about an axis where each rotation is dependent upon the preceding rotation. As such, the Euler angles need to be regarded as a set to get accurate angle information. Unfortunately, it is often difficult to visualize and understand these complex motion representations. One of our key functions is to help design engineers understand how a human will perform with new designs and all too often traditional use of Euler rotations becomes as much of a hindrance as a help. It is believed that using a spherical coordinate system will allow ABF personnel to more quickly and easily transmit important mobility data to engineers, in a format that is readily understandable and directly translatable to their design efforts. Objectives: The goal of this project is to establish new analysis and visualization techniques to aid in the examination and comprehension of complex motions. Methods: This project consisted of a series of small sub-projects, meant to validate and verify the method before it was implemented in the ABF's data analysis practices. The first stage was a proof of concept, where a mechanical test rig was built and instrumented with an inclinometer, so that its angle from horizontal was known. The test rig was tracked in 3D using an optical motion capture system, and its position and orientation were reported in both Euler and spherical reference systems. The rig was meant to simulate flexion/extension, transverse rotation and abduction/adduction of the human shoulder, but without the variability inherent in human motion. In the second phase of the project, the ABF estimated the error inherent in a spherical coordinate system, and evaluated how this error would vary within the reference frame. This stage also involved expanding a kinematic model of the shoulder, to include the torso, knees, ankle, elbows, wrists and neck. Part of this update included adding a representation of 'roll' about an axis, for upper arm and lower leg rotations. The third stage of the project involved creating visualization methods to assist in interpreting motion in a spherical frame. This visualization method will be incorporated in a tool to evaluate a database of suited mobility data, which is currently in development.
Streamlining CASTOR to manage the LHC data torrent
Lo Presti, G.; Espinal Curull, X.; Cano, E.; Fiorini, B.; Ieri, A.; Murray, S.; Ponce, S.; Sindrilaru, E.
2014-06-01
This contribution describes the evolution of the main CERN storage system, CASTOR, as it manages the bulk data stream of the LHC and other CERN experiments, achieving over 90 PB of stored data by the end of LHC Run 1. This evolution was marked by the introduction of policies to optimize the tape sub-system throughput, going towards a cold storage system where data placement is managed by the experiments' production managers. More efficient tape migrations and recalls have been implemented and deployed where bulk meta-data operations greatly reduce the overhead due to small files. A repack facility is now integrated in the system and it has been enhanced in order to automate the repacking of several tens of petabytes, required in 2014 in order to prepare for the next LHC run. Finally the scheduling system has been evolved to integrate the internal monitoring. To efficiently manage the service a solid monitoring infrastructure is required, able to analyze the logs produced by the different components (about 1 kHz of log messages). A new system has been developed and deployed, which uses a transport messaging layer provided by the CERN-IT Agile Infrastructure and exploits technologies including Hadoop and HBase. This enables efficient data mining by making use of MapReduce techniques, and real-time data aggregation and visualization. The outlook for the future is also presented. Directions and possible evolution will be discussed in view of the restart of data taking activities.
Alkalizing reactions streamline cellular metabolism in acidogenic microorganisms.
Stefania Arioli
Full Text Available An understanding of the integrated relationships among the principal cellular functions that govern the bioenergetic reactions of an organism is necessary to determine how cells remain viable and optimise their fitness in the environment. Urease is a complex enzyme that catalyzes the hydrolysis of urea to ammonia and carbonic acid. While the induction of urease activity by several microorganisms has been predominantly considered a stress-response that is initiated to generate a nitrogen source in response to a low environmental pH, here we demonstrate a new role of urease in the optimisation of cellular bioenergetics. We show that urea hydrolysis increases the catabolic efficiency of Streptococcus thermophilus, a lactic acid bacterium that is widely used in the industrial manufacture of dairy products. By modulating the intracellular pH and thereby increasing the activity of β-galactosidase, glycolytic enzymes and lactate dehydrogenase, urease increases the overall change in enthalpy generated by the bioenergetic reactions. A cooperative altruistic behaviour of urease-positive microorganisms on the urease-negative microorganisms within the same environment was also observed. The physiological role of a single enzymatic activity demonstrates a novel and unexpected view of the non-transcriptional regulatory mechanisms that govern the bioenergetics of a bacterial cell, highlighting a new role for cytosol-alkalizing biochemical pathways in acidogenic microorganisms.
Streamlining and automation of radioanalytical methods at a commercial laboratory
Harvey, J.T.; Dillard, J.W. [IT Corp., Knoxville, TN (United States)
1993-12-31
Through the careful planning and design of laboratory facilities and incorporation of modern instrumentation and robotics systems, properly trained and competent laboratory associates can efficiently and safely handle radioactive and mixed waste samples. This paper addresses the potential improvements radiochemistry and mixed waste laboratories can achieve utilizing robotics for automated sample analysis. Several examples of automated systems for sample preparation and analysis will be discussed.
Streamlining the Acquisition Process: A DCAA Field-Grade Perspective
2014-03-01
Initial Capabilities Document IFRS International Financial Reporting Standards IPT Integrated Product Team IRR Independent Reference Review...understanding and familiarity with the guidelines. Foreign companies generally adhere to International Financial Reporting Standards ( IFRS ), if any...U.S. GAAP vs. IFRS : The Basics. New York, NY: Ernst & Young, 2009. 88 THIS PAGE INTENTIONALLY LEFT BLANK 89 INITIAL DISTRIBUTION LIST 1. Defense
A Streamlined Molecular Biology Module for Undergraduate Biochemistry Labs
Muth, Gregory W.; Chihade, Joseph W.
2008-01-01
Site-directed mutagenesis and other molecular biology techniques, including plasmid manipulation and restriction analysis, are commonly used tools in the biochemistry research laboratory. In redesigning our biochemistry lab curricula, we sought to integrate these techniques into a term-long, project-based course. In the module presented here,…
Streamlining Transportation Corridor Planning Processess: Freight and Traffic Information
Franzese, Oscar [ORNL
2010-08-01
The traffic investigation is one of the most important parts of an Environmental Impact Statement of projects involving the construction of new roadway facilities and/or the improvement of existing ones. The focus of the traffic analysis is on the determination of anticipated traffic flow characteristics of the proposed project, by the application of analytical methods that can be grouped under the umbrella of capacity analysis methodologies. In general, the main traffic parameter used in EISs to describe the quality of traffic flow is the Level of Service (LOS). The current state of the practice in terms of the traffic investigations for EISs has two main shortcomings. The first one is related to the information that is necessary to conduct the traffic analysis, and specifically to the lack of integration among the different transportation models and the sources of information that, in general, reside in GIS databases. A discussion of the benefits of integrating CRS&SI technologies and the transportation models used in the EIS traffic investigation is included. The second shortcoming is in the presentation of the results, both in terms of the appearance and formatting, as well as content. The presentation of traffic results (current and proposed) is discussed. This chapter also addresses the need of additional data, in terms of content and coverage. Regarding the former, other traffic parameters (e.g., delays) that are more meaningful to non-transportation experts than LOS, as well as additional information (e.g., freight flows) that can impact traffic conditions and safety are discussed. Spatial information technologies can decrease the negative effects of, and even eliminate, these shortcomings by making the relevant information that is input to the models more complete and readily available, and by providing the means to communicate the results in a more clear and efficient manner. The benefits that the application and use of CRS&SI technologies can provide to improve and expedite the traffic investigation part of the EIS process are presented.
Streamline and Improve the Targeting of Education Tax Benefits
Institute for College Access & Success, 2014
2014-01-01
This one-page document presents The Institute for College Access & Success' (TICAS') recommendations for ways to improve the targeting of higher education tax benefits. The TICAS white paper, "Aligning the Means and the Ends: How to Improve Federal Student Aid and Increase College Access and Success," recommends almost entirely…
SWOT ANALYSIS-MANAGEMENT TECHNIQUES TO STREAMLINE PUBLIC BUSINESS MANAGEMENT
Rodica IVORSCHI
2012-01-01
SWOT analysis is the most important management techniques for understanding the strategic position of an organization. Objective SWOT analysis is to recommend strategies to ensure the best alignment between internal and external environment, and choosing the right strategy can be benefi cial organization in order to adapt their strengths to opportunities, minimize risks and eliminate weaknesses.
Severe Raynaud's phenomenon-A streamlined approach to acute management.
Lee, Regent; Lomas, Oliver; Handa, Ashok
2011-01-01
Raynaud's phenomenon is an exaggerated vasospastic response to cold or emotional stress which not only may cause the patient severe pain but also critical ischaemia and necrosis of the digits. We report the case of a 69-year-old woman who presented with rest pain, impending ulceration and necrosis of finger tips due to an episode of left-sided Raynaud's phenomenon. Intravenous prostacyclin was administered successfully as a bridge to endoscopic thoracic sympathectomy. Vascular surgery units are ideally positioned for the acute management of severe Raynaud's phenomenon to provide continuity of care to patients with profound digital ischaemia and impending tissue loss.
Aligning BIM with FM: streamlining the process for future projects
Colleen Kasprzak
2015-10-01
Full Text Available A study performed by the National Institute of Standards and Technology (NIST, USA in 2004 found that owners account for approximately $10.6 billion of the $15.8 billion total inadequate interoperability costs of U.S. capital facility projects in 2002. Because of these inefficiency costs, it becomes vital that information produced during the design and construction phases of a project be transferred into operations with maximum leverage to the end users. However, very few owners have defined these informational needs or developed an integration strategy into existing maintenance management systems. To increase operational efficiency, an organization must first develop an understanding of their operating systems, as well as identify how Building Information Modeling (BIM will add value to their daily tasks. The Pennsylvania State University (PSU has a unique opportunity to diversely implement BIM processes because not only does the University act as an owner, but also as designer and construction manager on the majority of projects. The struggle that PSU faces is one that is unique only to owners with a large, existing, multifaceted building inventory. This paper outlines the current initiative by the Office of Physical Plant (OPP, the asset manager at PSU, to develop an information exchange framework between BIM and FM applications to be used internally. As a result of this research, PSU has been able to define owner operational requirements for future projects and develop a flexible integration framework to support additional BIM tasks and information exchanges.
Streamlining Data for Cross-Platform Web Delivery
Watkins, Sean; Battles, Jason; Vacek, Rachel
2013-01-01
Smartphone users expect the presentation of Web sites on their mobile browsers to look and feel like native applications. With the pressure on library Web developers to produce app-like mobile sites, there is often a rush to get a site up without considering the importance of reusing or even restructuring the data driving the Web sites. An…
Streamlining Infrastructure Monitoring and Metrics in IT- DB-IMS
Newey, Charles Callum; Tenaglia, Giacomo; Wiecek, Artur
2015-01-01
Project Specification Basic Systems Monitoring This is now done with a CERN-made custom collector which sends data in the form of "notifications" via Apache Flume to HDFS for long-term storage. The notifications are also sent to ElasticSearch and displayed with Kibana (à la Splunk). Due to limitations of the architecture, the system data is collected every 5 minutes which is not ideal. The idea is to implement a solution which allows more fine-grained sampling of system...
SWOT ANALYSIS-MANAGEMENT TECHNIQUES TO STREAMLINE PUBLIC BUSINESS MANAGEMENT
Rodica IVORSCHI
2012-06-01
Full Text Available SWOT analysis is the most important management techniques for understanding the strategic position of an organization.Objective SWOT analysis is to recommend strategies to ensure the best alignment between internal and external environment, and choosing the right strategy can be beneficial organization in order to adapt their strengths to opportunities, minimize risks and eliminate weaknesses.
Halal Supply Chain Management Streamlined Practices: Issues and Challenges
Hijrah Abd Kadir, Muhammad; Zuraidah Raja Mohd Rasi, Raja; Omar, Siti Sarah; Manap, Zariq Imran Abdul
2016-11-01
The quickly developing worldwide halal in business sector has given a remarkable window of chance, which empowers Malaysia to the renowned halal centre in worldwide (known as Halal-hubs). Malaysia also has proactively taken a lead in halal activities, which is presently considered as the benchmark for a halal framework worldwide. Malaysia also set up the Halal Industry Development Corporation (HDC) which driving a wide range of halal activities since the demand of halal food has increased significantly which is very crucial for a Muslim in ensuring its authenticity and integrity. Even in parallel to this developments, many studies has been conducted because there are many issues still occurs in the food industry. The issue of consumer awareness and understanding the halal principles, mixing of halal and non- halal products, halal certification and logo compliance with Shariah law and lack of regulation and enforcement need the serious attention by all parties along the supply chain. The challenges occur mainly in the halal food segregation and halal traceability of the products. The unit of analysis in this study different halal stakeholders group which are JAKIM, Halal Development Centre (HDC), Raw Material Manufacturers, Retailers and Government Agencies. This paper attempt discusses the issues and challenges occurs in the halal supply chain and faced by the practitioners as well as the relevant parties involved in the industry especially for food products manufacturers. The study would like to give a basic information about the issues and challenges in the contribution of Halal Supply Chain Management (HSCM) as well as for the future studies.
Streamlining the Process of Acquiring Secure Open Architecture Software Systems
2013-04-01
Office of Small Business Programs, Department of the Navy Director, Office of Acquisition Resources and Analysis ( ARA ) Deputy Assistant...innovative ways and means to acquire/develop component-based OA software systems that are subject to diverse, heterogeneous IP licenses (Alspaugh... heterogeneously licensed systems. Journal of the Association for Information Systems, 11(11), 730–755. Anderson, S. (2012, July-September). Software
Yasuhara, S.
2013-12-01
The ability to measure the isotopic composition of matrix-bound water is valuable to many facets of earth and environmental sciences. For example, ecohydrologists use stable isotopes of oxygen and hydrogen in plant and soil water, in combination with measurements of atmospheric water vapor, surface water and precipitation, to estimate budgets of evapotranspiration. Likewise, water isotopes of oceanic water, brines and other waters with high total dissolved solids (TDS, e.g., juices) are relevant to studying large-scale oceanic circulation, small-scale mixing, groundwater contamination, the balance of evaporation to precipitation, and the provenance of food. Conventionally matrix-bound water has been extracted using cryogenic distillation, whereby water is distilled from the material in question (e.g., a leaf sample) by heating under vacuum and collecting the resultant water vapor using liquid nitrogen. The water can then be analyzed for its stable isotopic composition by a variety of methods, including isotope ratio mass spectrometry and laser techniques, such as Cavity Ring-Down Spectroscopy (CRDS). Here we present recent improvements in an alternative, and stream-lined, solution for integrated sample extraction and isotopic measurement using a Picarro Induction Module (IM) coupled to commercially-available CRDS analyzer from Picarro. This technique is also valuable for waters with high TDS, which can have detrimental effects on flash vaporization process, typically used for the introduction of water to Picarro CRDS water isotope analyzers. The IM works by inductively heating a sample held within a metal sample holder in a glass vial flushed with dry air. Tested samples include leaves, stems, twigs, calibration water, juices, and salt water. The heating process evolves water vapor which is then swept through the system at approximately 150 standard cubic centimeters per minute. The evolved water vapor passes through an activated charcoal cartridge for removal of
Numerical model of the solidification of alloys with natural convection of the liquid
E. Węgrzyn-Skrzypczak
2008-04-01
Full Text Available The paper deals with comparison of numerical analysis results obtained for binary alloys solidification process in the sand and permanent mould with motion of the fluid in the liquid and mushy zone. The partial differential equations describing mathematical model of the phenomena are presented. Finite Element Method is used for modeling process. Characteristic Based Split (CBS method is used for solving momentum equation. Such approach allows to uncouple velocities and pressure. Petrov-Galerkin formulation is employed to stabilize heat conductivity equation with convective term. The results of the numerical simulations in the 2D region are discussed. Velocity fields, cooling rates and positions of the liquid, solid-liquid and solid regions are compared.
Shadid, J.N.; Tuminaro, R.S. [Sandia National Labs., Albuquerque, NM (United States); Walker, H.F. [Utah State Univ., Logan, UT (United States). Dept. of Mathematics and Statistics
1997-02-01
The solution of the governing steady transport equations for momentum, heat and mass transfer in flowing fluids can be very difficult. These difficulties arise from the nonlinear, coupled, nonsymmetric nature of the system of algebraic equations that results from spatial discretization of the PDEs. In this manuscript the authors focus on evaluating a proposed nonlinear solution method based on an inexact Newton method with backtracking. In this context they use a particular spatial discretization based on a pressure stabilized Petrov-Galerkin finite element formulation of the low Mach number Navier-Stokes equations with heat and mass transport. The discussion considers computational efficiency, robustness and some implementation issues related to the proposed nonlinear solution scheme. Computational results are presented for several challenging CFD benchmark problems as well as two large scale 3D flow simulations.
Shadid, J.N.; Tuminaro, R.S. [Sandia National Labs., Albuquerque, NM (United States); Walker, H.F. [Utah State Univ., Logan, UT (United States). Dept. of Mathematics and Statistics
1997-02-01
The solution of the governing steady transport equations for momentum, heat and mass transfer in flowing fluids can be very difficult. These difficulties arise from the nonlinear, coupled, nonsymmetric nature of the system of algebraic equations that results from spatial discretization of the PDEs. In this manuscript the authors focus on evaluating a proposed nonlinear solution method based on an inexact Newton method with backtracking. In this context they use a particular spatial discretization based on a pressure stabilized Petrov-Galerkin finite element formulation of the low Mach number Navier-Stokes equations with heat and mass transport. The discussion considers computational efficiency, robustness and some implementation issues related to the proposed nonlinear solution scheme. Computational results are presented for several challenging CFD benchmark problems as well as two large scale 3D flow simulations.
Approximation of weak adjoints by reverse automatic differentiation of BDF methods
Beigel, Dörte; Wirsching, Leonard; Bock, Hans Georg
2011-01-01
With this contribution, we shed light on the relation between the discrete adjoints of multistep backward differentiation formula (BDF) methods and the solution of the adjoint differential equation. To this end, we develop a functional-analytic framework based on a constrained variational problem and introduce the notion of weak adjoint solutions. We devise a finite element Petrov-Galerkin interpretation of the BDF method together with its discrete adjoint scheme obtained by reverse internal numerical differentiation. We show how the finite element approximation of the weak adjoint is computed by the discrete adjoint scheme and prove its asymptotic convergence in the space of normalized functions of bounded variation. We also obtain asymptotic convergence of the discrete adjoints to the classical adjoints on the inner time interval. Finally, we give numerical results for non-adaptive and fully adaptive BDF schemes. The presented framework opens the way to carry over the existing theory on global error estimat...
Influence of coolant motion on structure of hardened steel element
A. Kulawik
2008-08-01
Full Text Available Presented paper is focused on volumetric hardening process using liquid low melting point metal as a coolant. Effect of convective motion of the coolant on material structure after hardening is investigated. Comparison with results obtained for model neglecting motion of liquid is executed. Mathematical and numerical model based on Finite Element Metod is described. Characteristic Based Split (CBS method is used to uncouple velocities and pressure and finally to solve Navier-Stokes equation. Petrov-Galerkin formulation is employed to stabilize convective term in heat transport equation. Phase transformations model is created on the basis of Johnson-Mehl and Avrami laws. Continuous cooling diagram (CTPc for C45 steel is exploited in presented model of phase transformations. Temporary temperatures, phases participation, thermal and structural strains in hardening element and coolant velocities are shown and discussed.
Inverse Crack Problems in Piezoelectric Solids
Sladek, Jan; Sladek, Vladimir; Zhang, Chuanzeng
2010-05-01
In the present paper, the meshless local Petrov-Galerkin (MLPG) method is applied to cracked piezoelectric solids under a stationary or transient dynamic load and unspecified electrical conditions on the crack surfaces. On the outer surface of the cracked solid the electrical boundary conditions are over-specified. The coupled governing partial differential equations are satisfied in a weak-form on small fictitious sub-domains. Nodal points are introduced and spread on the analyzed domain and each node is surrounded by a small circle for simplicity, but without loss of generality. The spatial variations of the displacements and the electric potential are approximated by the Moving Least-Squares (MLS) scheme. After performing the spatial integrations, a system of linear algebraic equations for unknown nodal values is obtained. Singular value decomposition (SVD) is applied to solve the ill-conditioned linear system of algebraic equations obtained from the local integral equations (LIEs) after the MLS approximation.
Analytical vs. Simulation Solution Techniques for Pulse Problems in Non-linear Stochastic Dynamics
Iwankiewicz, R.; Nielsen, Søren R. K.
-numerical techniques suitable for Markov response problems such as moments equation, Petrov-Galerkin and cell-to-cell mapping techniques are briefly discussed. Usefulness of these techniques is limited by the fact that effectiveness of each of them depends on the mean rate of impulses. Another limitation is the size...... of the problem, i.e. the number of state variables of the dynamical systems. In contrast, the application of the simulation techniques is not limited to Markov problems, nor is it dependent on the mean rate of impulses. Moreover their use is straightforward for a large class of point processes, at least......Advantages and disadvantages of available analytical and simulation techniques for pulse problems in non-linear stochastic dynamics are discussed. First, random pulse problems, both those which do and do not lead to Markov theory, are presented. Next, the analytical and analytically...
A Numerical Solution for Hirota-Satsuma Coupled KdV Equation
M. S. Ismail
2014-01-01
Full Text Available A Petrov-Galerkin method and product approximation technique are used to solve numerically the Hirota-Satsuma coupled Korteweg-de Vries equation, using cubic B-splines as test functions and a linear B-spline as trial functions. The implicit midpoint rule is used to advance the solution in time. Newton’s method is used to solve the block nonlinear pentadiagonal system we have obtained. The resulting schemes are of second order accuracy in both directions, space and time. The von Neumann stability analysis of the schemes shows that the two schemes are unconditionally stable. The single soliton solution and the conserved quantities are used to assess the accuracy and to show the robustness of the schemes. The interaction of two solitons, three solitons, and birth of solitons is also discussed.
A class of discontinuous Petrov–Galerkin methods. Part III: Adaptivity
Demkowicz, Leszek
2012-04-01
We continue our theoretical and numerical study on the Discontinuous Petrov-Galerkin method with optimal test functions in context of 1D and 2D convection-dominated diffusion problems and hp-adaptivity. With a proper choice of the norm for the test space, we prove robustness (uniform stability with respect to the diffusion parameter) and mesh-independence of the energy norm of the FE error for the 1D problem. With hp-adaptivity and a proper scaling of the norms for the test functions, we establish new limits for solving convection-dominated diffusion problems numerically: ε=10 -11 for 1D and ε=10 -7 for 2D problems. The adaptive process is fully automatic and starts with a mesh consisting of few elements only. © 2011 IMACS. Published by Elsevier B.V. All rights reserved.
Multiscale stabilization for convection-dominated diffusion in heterogeneous media
Calo, Victor M.
2016-02-23
We develop a Petrov-Galerkin stabilization method for multiscale convection-diffusion transport systems. Existing stabilization techniques add a limited number of degrees of freedom in the form of bubble functions or a modified diffusion, which may not be sufficient to stabilize multiscale systems. We seek a local reduced-order model for this kind of multiscale transport problems and thus, develop a systematic approach for finding reduced-order approximations of the solution. We start from a Petrov-Galerkin framework using optimal weighting functions. We introduce an auxiliary variable to a mixed formulation of the problem. The auxiliary variable stands for the optimal weighting function. The problem reduces to finding a test space (a dimensionally reduced space for this auxiliary variable), which guarantees that the error in the primal variable (representing the solution) is close to the projection error of the full solution on the dimensionally reduced space that approximates the solution. To find the test space, we reformulate some recent mixed Generalized Multiscale Finite Element Methods. We introduce snapshots and local spectral problems that appropriately define local weight and trial spaces. In particular, we use energy minimizing snapshots and local spectral decompositions in the natural norm associated with the auxiliary variable. The resulting spectral decomposition adaptively identifies and builds the optimal multiscale space to stabilize the system. We discuss the stability and its relation to the approximation property of the test space. We design online basis functions, which accelerate convergence in the test space, and consequently, improve stability. We present several numerical examples and show that one needs a few test functions to achieve an error similar to the projection error in the primal variable irrespective of the Peclet number.
Application research of the MLPG mixed collocation method in shape optimization%MLPG混合配点法在形状优化中的应用研究
赵亮; 李书; 鲁大伟
2011-01-01
建立了无网格MLPG(Meshless Local Petrov-Galerkin)混合配点法求解二维弹性体位移、应力的数学模型,使用罚函数法添加本质边界条件,并将其应用到结构形状优化,结合遗传算法提出了一种新的连续体结构优化设计方法.对于节点支持域半径的选取进行了重点探讨,提出一种动态支持域选择方法,建立了基于MLPG混合配点法的优化模型,对两个实际工程算例进行了形状优化,并与现有结果比较,验证了该方法的有效性.%The mathematics model of the MLPG (the Meshless Local Petrov-Galerkin) mixed collocation method is built for solving the displacement and stress of 2-D elasticity, and the essential boundary condition is imposed by penalty function method, which is applied in structure shape optimization.A new design method of continuum structure is proposed with MLPG mixed collocation method and Genetic Algorithm.The select of node's support domain radius is mainly discussed and a dynamic support domain radius chosen method is given.An optimization model is presented based on MLPG mixed collocation method.Numerical examples show that the proposed method is effective.