Fast space-varying convolution using matrix source coding with applications to camera stray light reduction.

Science.gov (United States)

Wei, Jianing; Bouman, Charles A; Allebach, Jan P

2014-05-01

Many imaging applications require the implementation of space-varying convolution for accurate restoration and reconstruction of images. Here, we use the term space-varying convolution to refer to linear operators whose impulse response has slow spatial variation. In addition, these space-varying convolution operators are often dense, so direct implementation of the convolution operator is typically computationally impractical. One such example is the problem of stray light reduction in digital cameras, which requires the implementation of a dense space-varying deconvolution operator. However, other inverse problems, such as iterative tomographic reconstruction, can also depend on the implementation of dense space-varying convolution. While space-invariant convolution can be efficiently implemented with the fast Fourier transform, this approach does not work for space-varying operators. So direct convolution is often the only option for implementing space-varying convolution. In this paper, we develop a general approach to the efficient implementation of space-varying convolution, and demonstrate its use in the application of stray light reduction. Our approach, which we call matrix source coding, is based on lossy source coding of the dense space-varying convolution matrix. Importantly, by coding the transformation matrix, we not only reduce the memory required to store it; we also dramatically reduce the computation required to implement matrix-vector products. Our algorithm is able to reduce computation by approximately factoring the dense space-varying convolution operator into a product of sparse transforms. Experimental results show that our method can dramatically reduce the computation required for stray light reduction while maintaining high accuracy.

Effects of stray lights on Faraday rotation measurement for polarimeter-interferometer system on EAST.

Science.gov (United States)

Zou, Z Y; Liu, H Q; Ding, W X; Chen, J; Brower, D L; Lian, H; Wang, S X; Li, W M; Yao, Y; Zeng, L; Jie, Y X

2018-01-01

A double-pass radially view 11 chords polarimeter-interferometer system has been operated on the experimental advanced superconducting tokamak and provides important current profile information for plasma control. Stray light originating from spurious reflections along the optical path (unwanted reflections from various optical components/mounts and transmissive optical elements such as windows, waveplates, and lens as well as the detectors) and also direct feedback from the retro-reflector used to realize the double-pass configuration can both contribute to contamination of the Faraday rotation measurement accuracy. Modulation of the Faraday rotation signal due to the interference from multiple reflections is observable when the interferometer phase (plasma density) varies with time. Direct reflection from the detector itself can be suppressed by employing an optical isolator consisting of a λ/4-waveplate and polarizer positioned in front of the mixer. A Faraday angle oscillation during the density ramping up (or down) can be reduced from 5°-10° to 1°-2° by eliminating reflections from the detector. Residual modulation arising from misalignment and stray light from other sources must be minimized to achieve accurate measurements of Faraday rotation.

A high-power spatial filter for Thomson scattering stray light reduction

Science.gov (United States)

Levesque, J. P.; Litzner, K. D.; Mauel, M. E.; Maurer, D. A.; Navratil, G. A.; Pedersen, T. S.

2011-03-01

The Thomson scattering diagnostic on the High Beta Tokamak-Extended Pulse (HBT-EP) is routinely used to measure electron temperature and density during plasma discharges. Avalanche photodiodes in a five-channel interference filter polychromator measure scattered light from a 6 ns, 800 mJ, 1064 nm Nd:YAG laser pulse. A low cost, high-power spatial filter was designed, tested, and added to the laser beamline in order to reduce stray laser light to levels which are acceptable for accurate Rayleigh calibration. A detailed analysis of the spatial filter design and performance is given. The spatial filter can be easily implemented in an existing Thomson scattering system without the need to disturb the vacuum chamber or significantly change the beamline. Although apertures in the spatial filter suffer substantial damage from the focused beam, with proper design they can last long enough to permit absolute calibration.

STRAY - An interactive program for the computation of stray radiation in infrared telescopes

Science.gov (United States)

St. Clair Dinger, Ann

1987-01-01

The STRAY program to model the amount of stray radiation reaching the focal plane of a well-baffled telescope is described. The STRAY telescope model is addressed, including the aperture shade, barrel baffle, optics, mirror sectioning and chopping, and off-axis points in focal plane. The possible illumination paths are shown, and calculation options using STRAY are discussed. The stored data and computational aspects of STRAY are addressed. STRAY is compared to the MINI-APART model, and applications of STRAY are described.

Stray radiation and the Infrared Astronomical Satellite /IRAS/ telescope

Science.gov (United States)

Noll, R. J.; Harned, R.; Breault, R. P.; Malugin, R.

1981-01-01

Stray light control is a major consideration in the design of infrared cryogenically cooled telescopes such as the Infrared Astronomical Satellite (IRAS). The basic design of the baffle system, and the placement, shape, and coating of the secondary support struts for the telescope subsystem are described. The intent of this paper is to highlight the stray light problems encountered while designing the system, and to illustrate how computer analysis can be a useful design aid. Scattering measurements of the primary mirror, and a full system level scatter measurement are presented. Comparisons of predicted performance with the measured results are also presented.

Stray voltage mitigation

Energy Technology Data Exchange (ETDEWEB)

Jamali, B.; Piercy, R.; Dick, P. [Kinetrics Inc., Toronto, ON (Canada). Transmission and Distribution Technologies

2008-04-09

This report discussed issues related to farm stray voltage and evaluated mitigation strategies and costs for limiting voltage to farms. A 3-phase, 3-wire system with no neutral ground was used throughout North America before the 1930s. Transformers were connected phase to phase without any electrical connection between the primary and secondary sides of the transformers. Distribution voltage levels were then increased and multi-grounded neutral wires were added. The earth now forms a parallel return path for the neutral current that allows part of the neutral current to flow continuously through the earth. The arrangement is responsible for causing stray voltage. Stray voltage causes uneven milk production, increased incidences of mastitis, and can create a reluctance to drink water amongst cows when stray voltages are present. Off-farm sources of stray voltage include phase unbalances, undersized neutral wire, and high resistance splices on the neutral wire. Mitigation strategies for reducing stray voltage include phase balancing; conversion from single to 3-phase; increasing distribution voltage levels, and changing pole configurations. 22 refs., 5 tabs., 13 figs.

An assessment of the stray light in 25 years of Dobson total ozone data at Athens, Greece

Science.gov (United States)

Christodoulakis, J.; Varotsos, C.; Cracknell, A. P.; Tzanis, C.; Neofytos, A.

2015-07-01

In this study, we investigated the susceptibility of the Dobson spectrophotometer No. 118 to stray light interference. In this regard, a series of total ozone content measurements were carried out in Athens, Greece for air-mass values (μ) extending up to μ = 5. The monochromatic-heterochromatic stray light derived by Basher's model was used in order to evaluate the specific instrumental parameters which determine if this instrument suffers from this problem or not. The results obtained indicate that the measurements made by the Dobson instrument of the Athens station for air mass values up to 2.5, underestimates the total ozone content by 3.5 DU in average, or about 1 % of the station's mean total ozone content (TOC). The comparison of the values of the same parameters measured 15 years ago with the present ones indicates the good maintenance of the Dobson spectrophotometer No. 118. This fact is of crucial importance because the variability of the daily total ozone observations collected by the Athens Dobson Station since 1989 has proved to be representative to the variability of the mean total ozone observed over the whole mid-latitude zone of the Northern Hemisphere. This stresses the point that the Athens total ozone station, being the unique Dobson station in south-eastern Europe, may be assumed as a ground truth station for the reliable conversion of the satellite radiance observations to total ozone measurements.

Scanning light-sheet microscopy in the whole mouse brain with HiLo background rejection

Science.gov (United States)

Mertz, Jerome; Kim, Jinhyun

2010-01-01

It is well known that light-sheet illumination can enable optically sectioned wide-field imaging of macroscopic samples. However, the optical sectioning capacity of a light-sheet macroscope is undermined by sample-induced scattering or aberrations that broaden the thickness of the sheet illumination. We present a technique to enhance the optical sectioning capacity of a scanning light-sheet microscope by out-of-focus background rejection. The technique, called HiLo microscopy, makes use of two images sequentially acquired with uniform and structured sheet illumination. An optically sectioned image is then synthesized by fusing high and low spatial frequency information from both images. The benefits of combining light-sheet macroscopy and HiLo background rejection are demonstrated in optically cleared whole mouse brain samples, using both green fluorescent protein (GFP)-fluorescence and dark-field scattered light contrast.

Low-Energy Microfocus X-Ray Source for Enhanced Testing Capability in the Stray Light Facility

Science.gov (United States)

Gaskin, Jessica; O'Dell, Stephen; Kolodziejczak, Jeff

2015-01-01

Research toward high-resolution, soft x-ray optics (mirrors and gratings) necessary for the next generation large x-ray observatories requires x-ray testing using a low-energy x-ray source with fine angular size (energy microfocus (approximately 0.1 mm spot) x-ray source from TruFocus Corporation that mates directly to the Stray Light Facility (SLF). MSFC X-ray Astronomy team members are internationally recognized for their expertise in the development, fabrication, and testing of grazing-incidence optics for x-ray telescopes. One of the key MSFC facilities for testing novel x-ray instrumentation is the SLF. This facility is an approximately 100-m-long beam line equipped with multiple x-ray sources and detectors. This new source adds to the already robust compliment of instrumentation, allowing MSFC to support additional internal and community x-ray testing needs.

Influence of excitation light rejection on forward model mismatch in optical tomography

International Nuclear Information System (INIS)

Hwang, K; Pan, T; Joshi, A; Rasmussen, J C; Bangerth, W; Sevick-Muraca, E M

2006-01-01

Fluorescence enhanced tomography for molecular imaging requires low background for detection and accurate image reconstruction. In this contribution, we show that excitation light leakage is responsible for elevated background and can be minimized with the use of gradient index (GRIN) lenses when using fibre optics to collect propagated fluorescence light from tissue or other biological media. We show that the model mismatch between frequency-domain photon migration (FDPM) measurements and the diffusion approximation prediction is decreased when GRIN lenses are placed prior to the interference filters to provide efficient excitation light rejection. Furthermore, model mismatch is correlated to the degree of excitation light leakage. This work demonstrates the importance of proper light filtering when designing fluorescence optical imaging and tomography

Detection of Hepatozoon canis in stray dogs and cats in Bangkok, Thailand.

Science.gov (United States)

Jittapalapong, Sathaporn; Rungphisutthipongse, Opart; Maruyama, Soichi; Schaefer, John J; Stich, Roger W

2006-10-01

A rapidly increasing stray animal population in Bangkok has caused concern regarding transmission of vector-borne and zoonotic diseases. The purpose of this study was to determine if stray animals in Bangkok are a potential reservoir of Hepatozoon, a genus of tick-borne parasites that has received little attention in Thailand. Blood samples were collected from stray companion animals near monasteries in 42 Bangkok metropolitan districts. Both dogs and cats were sampled from 26 districts, dogs alone from 4 districts and cats alone from 12 districts. Samples were collected from a total of 308 dogs and 300 cats. Light microscopy and an 18 S rRNA gene-based PCR assay were used to test these samples for evidence of Hepatozoon infection. Gamonts were observed in blood smears for 2.6% of dogs and 0.7% of cats by microscopy. The PCR assay detected Hepatozoon in buffy coats from 11.4% of dogs and 32.3% of cats tested. The prevalence of infection was the same between male and female dogs or cats, and PCR-positive dogs and cats were found in 36.6% and 36.8% of the districts surveyed, respectively. There was an association between the percentages of PCR-positive dogs and cats in districts where both host species were sampled. Sequences of representative amplicons were closest to those reported for H. canis. These results represent the first molecular confirmation that H. canis is indigenous to Thailand. The unexpectedly high prevalence of Hepatozoon among stray cats indicates that their role in the epizootiology of hepatozoonosis should be investigated.

STRAY DOG DETECTION IN WIRED CAMERA NETWORK

Directory of Open Access Journals (Sweden)

C. Prashanth

2013-08-01

Full Text Available Existing surveillance systems impose high level of security on humans but lacks attention on animals. Stray dogs could be used as an alternative to humans to carry explosive material. It is therefore imperative to ensure the detection of stray dogs for necessary corrective action. In this paper, a novel composite approach to detect the presence of stray dogs is proposed. The captured frame from the surveillance camera is initially pre-processed using Gaussian filter to remove noise. The foreground object of interest is extracted utilizing ViBe algorithm. Histogram of Oriented Gradients (HOG algorithm is used as the shape descriptor which derives the shape and size information of the extracted foreground object. Finally, stray dogs are classified from humans using a polynomial Support Vector Machine (SVM of order 3. The proposed composite approach is simulated in MATLAB and OpenCV. Further it is validated with real time video feeds taken from an existing surveillance system. From the results obtained, it is found that a classification accuracy of about 96% is achieved. This encourages the utilization of the proposed composite algorithm in real time surveillance systems.

Prevalence of external ear disorders in Belgian stray cats.

Science.gov (United States)

Bollez, Anouck; de Rooster, Hilde; Furcas, Alessandra; Vandenabeele, Sophie

2018-02-01

Objectives Feline otitis externa is a multifactorial dermatological disorder about which very little is known. The objective of this study was to map the prevalence of external ear canal disorders and the pathogens causing otitis externa in stray cats roaming around the region of Ghent, Belgium. Methods One hundred and thirty stray cats were randomly selected during a local trap-neuter-return programme. All cats were European Shorthairs. This study included clinical, otoscopic and cytological evaluation of both external ears of each cat. Prospective data used as parameters in this study included the sex, age and body condition score of each cat, as well as the presence of nasal and/or ocular discharge, and the results of feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) Snap tests. Results Remarkably, very few (sub)clinical problems of the external ear canal were found in the stray cat population. Malassezia species was by far the most common organism found in the external ear canals of the 130 stray cats. A total of 96/130 (74%) cats were found to have Malassezia species organisms present in one or both ears based on the cytological examination. No correlation was found between the parameters of sex, age, body condition score, the presence of nasal and/or ocular discharge and FIV and FeLV status, and the presence of parasites, bacteria or yeasts. Conclusions and relevance This study provides more information about the normal state of the external ear canal of stray cats. The ears of most stray cats are relatively healthy. The presence of Malassezia species organisms in the external ear canal is not rare among stray cats.

METIS: the visible and UV coronagraph for solar orbiter

Science.gov (United States)

Romoli, M.; Landini, F.; Antonucci, E.; Andretta, V.; Berlicki, A.; Fineschi, S.; Moses, J. D.; Naletto, G.; Nicolosi, P.; Nicolini, G.; Spadaro, D.; Teriaca, L.; Baccani, C.; Focardi, M.; Pancrazzi, M.; Pucci, S.; Abbo, L.; Bemporad, A.; Capobianco, G.; Massone, G.; Telloni, D.; Magli, E.; Da Deppo, V.; Frassetto, F.; Pelizzo, M. G.; Poletto, L.; Uslenghi, M.; Vives, S.; Malvezzi, M.

2017-11-01

METIS coronagraph is designed to observe the solar corona with an annular field of view from 1.5 to 2.9 degrees in the visible broadband (580-640 nm) and in the UV HI Lyman-alpha, during the Sun close approaching and high latitude tilting orbit of Solar Orbiter. The big challenge for a coronagraph is the stray light rejection. In this paper after a description of the present METIS optical design, the stray light rejection design is presented in detail together with METIS off-pointing strategies throughout the mission. Data shown in this paper derive from the optimization of the optical design performed with Zemax ray tracing and from laboratory breadboards of the occultation system and of the polarimeter.

Aerial firing and stray bullet injuries: a rising tide.

Science.gov (United States)

Ali, Syed Asad; Tahir, Syed Mohammad; Makhdoom, Asadullah; Shaikh, Abdul Razaque; Siddique, Akmal Jamal

2015-04-01

Aerial firing is shooting, using fire arm, into the air usually during a celebration. This observational study aimed to quantify magnitude and impact of stray bullet injuries by aerial firing at surgical emergencies of the Liaquat University Hospital (a university hospital), Hyderabad, Sindh, Pakistan from January 2009 to December 2010 (2 years). During the study period, 144 firearm injuries due to stray bullet reported to the A and E departments of the university hospital. All patients referred to surgical unit providing emergency cover on that day irrespective of the severity of the injury for medico-legal reasons. For this study, the cases were divided into those having trivial injury and do not require any active surgical intervention and those having serious injury mandating surgical intervention. One hundred and two cases of stray bullet injury sustained trivial injury and followed as outpatients after an overnight period of indoor hospitalization; however, 42 patients with stray bullet injuries requiring surgical intervention were hospitalized. The most common events leading to aerial firing and stray bullet injuries were marriage ceremonies, followed by a political rallies and New Year celebrations. Stray bullet injury also reported after aerial firing on cricket/hockey team victories, Pakistan Independence Day (14th August), cultural day in Sindh and Basant (Kite) festival in Punjab. The most frequent sites with serious stray bullet injury were chest (15), head and neck (10), abdomen (9) and limbs (8), respectively. Surgical interventions performed included chest intubation, exploration of wound tract to retrieve bullet if lodged superficially and was palpable, laparotomy to managed intra-abdominal injury, reduction of fracture site followed by reconstruction, flap reconstruction and graft for nonhealing wound. The mean duration of hospital stay was 19 days. No mortality was observed in this series of patients. We conclude that the prevalence of aerial

Monitoring dc stray current corrosion at sheet pile structures

NARCIS (Netherlands)

Peelen, W.H.A.; Neeft, E.A.C.; Leegwater, G.; Kanten-Roos, W. van; Courage, W.M.G.

2012-01-01

Steel is discarded by railway owners as a material for underground structures near railway lines, due to uncertainty over increased corrosion by DC stray currents stemming from the traction power system. This paper presents a large scale field test in which stray currents interference of a sheet

The Disturbing Effect of the Stray Magnetic Fields on Magnetoimpedance Sensors

Directory of Open Access Journals (Sweden)

Tao Wang

2016-10-01

Full Text Available The disturbing effect of the stray magnetic fields of Fe-based amorphous ribbons on the giant magnetoimpedance (GMI sensor has been investigated systematically in this paper. Two simple methods were used for examining the disturbing effect of the stray magnetic fields of ribbons on the GMI sensor. In order to study the influence of the stray magnetic fields on the GMI effect, the square-shaped amorphous ribbons were tested in front, at the back, on the left and on the top of a meander-line GMI sensor made up of soft ferromagnetic films, respectively. Experimental results show that the presence of ribbons in front or at the back of GMI sensor shifts the GMI curve to a lower external magnetic field. On the contrary, the presence of ribbons on the left or on the top of the GMI sensor shifts the GMI curve to a higher external magnetic field, which is related to the coupling effect of the external magnetic field and the stray magnetic fields. The influence of the area and angle of ribbons on GMI was also studied in this work. The GMI sensor exhibits high linearity for detection of the stray magnetic fields, which has made it feasible to construct a sensitive magnetometer for detecting the typical stray magnetic fields of general soft ferromagnetic materials.

Double-grating polychromator for laser-aided plasma diagnostics

International Nuclear Information System (INIS)

Mukhin, E.E.; Razdobarin, G.T.; Semenov, V.V.; Shilnikov, A.N.; Sukhanov, V.L.; Tolstjakov, S.Yu.; Kochergin, M.M.; Mihailovskij, Yu.K.; Bakh, L.I.

2004-01-01

A wide bandpass double-grating polychromator with high rejection and high transmission has been designed and manufactured for laser-aided plasma diagnostics. The special mount utilizes subtractive dispersion in the second stage of the double polychromator such that the larger dispersion of the second stage is reduced by that of the first stage. This affects the intensity of the stray light background at the laser wavelength. The background at the edge of the laser line was measured at 10 -5 of the light incident on the input slit. At the short end of the 200 nm bandpass, the stray light relative intensity approached 10 -7

The quality of stray radiation in the ovarian region in diagnostic X-ray examinations

International Nuclear Information System (INIS)

Ewen, K.; Fiebach, B.J.O.; Fischer, P.G.; Loehr, E.

1976-01-01

Dose measurements (LiF-TLD) and recordings of stray radiation spectra (Ge(Li)-Detectors) in a phantom show that shielding of the ovaries against stray radiation is advisable even though the effectivity of this measure decreases at higher tube voltages. The exposure of the ovaries to stray radiation increases with increasing tube voltage; the radiation quality of the stray radiation is, for the most part, independent of the filter value. (orig./AK) [de

VIBRATIONAL SPECTRA OF t-BUTYL ALCOHOL, t-BUTYLAMINE ...

African Journals Online (AJOL)

a

good stray light rejection. A Spectra-Physics ... the spectrometer. The vial was then spun to enhance the Raman signal and reduce the risk of .... *Abbreviations used: m, medium; s, strong; v, very; w, weak; sh, shoulder; -, not detected due to the ...

Stray energy transfer during endoscopy.

Science.gov (United States)

Jones, Edward L; Madani, Amin; Overbey, Douglas M; Kiourti, Asimina; Bojja-Venkatakrishnan, Satheesh; Mikami, Dean J; Hazey, Jeffrey W; Arcomano, Todd R; Robinson, Thomas N

2017-10-01

Endoscopy is the standard tool for the evaluation and treatment of gastrointestinal disorders. While the risk of complication is low, the use of energy devices can increase complications by 100-fold. The mechanism of increased injury and presence of stray energy is unknown. The purpose of the study was to determine if stray energy transfer occurs during endoscopy and if so, to define strategies to minimize the risk of energy complications. A gastroscope was introduced into the stomach of an anesthetized pig. A monopolar generator delivered energy for 5 s to a snare without contacting tissue or the endoscope itself. The endoscope tip orientation, energy device type, power level, energy mode, and generator type were varied to mimic in vivo use. The primary outcome (stray current) was quantified as the change in tissue temperature (°C) from baseline at the tissue closest to the tip of the endoscope. Data were reported as mean ± standard deviation. Using the 60 W coag mode while changing the orientation of the endoscope tip, tissue temperature increased by 12.1 ± 3.5 °C nearest the camera lens (p energy transfer (p = 0.04 and p = 0.002, respectively) as did utilizing the low-voltage cut mode (6.6 ± 0.5 °C, p energy transfer compared to a standard generator (1.5 ± 3.5 °C vs. 9.5 ± 0.8 °C, p energy is transferred within the endoscope during the activation of common energy devices. This could result in post-polypectomy syndrome, bleeding, or perforation outside of the endoscopist's view. Decreasing the power, utilizing low-voltage modes and/or an impedance-monitoring generator can decrease the risk of complication.

A method to measure internal stray radiation of cryogenic infrared imaging systems under various ambient temperatures

Science.gov (United States)

Tian, Qijie; Chang, Songtao; Li, Zhou; He, Fengyun; Qiao, Yanfeng

2017-03-01

The suppression level of internal stray radiation is a key criterion for infrared imaging systems, especially for high-precision cryogenic infrared imaging systems. To achieve accurate measurement for internal stray radiation of cryogenic infrared imaging systems under various ambient temperatures, a measurement method, which is based on radiometric calibration, is presented in this paper. First of all, the calibration formula is deduced considering the integration time, and the effect of ambient temperature on internal stray radiation is further analyzed in detail. Then, an approach is proposed to measure the internal stray radiation of cryogenic infrared imaging systems under various ambient temperatures. By calibrating the system under two ambient temperatures, the quantitative relation between the internal stray radiation and the ambient temperature can be acquired, and then the internal stray radiation of the cryogenic infrared imaging system under various ambient temperatures can be calculated. Finally, several experiments are performed in a chamber with controllable inside temperatures to evaluate the effectiveness of the proposed method. Experimental results indicate that the proposed method can be used to measure internal stray radiation with high accuracy at various ambient temperatures and integration times. The proposed method has some advantages, such as simple implementation and the capability of high-precision measurement. The measurement results can be used to guide the stray radiation suppression and to test whether the internal stray radiation suppression performance meets the requirement or not.

Stray capacitances in the watt balance operation: electrostatic forces

DEFF Research Database (Denmark)

Quagliotti, Danilo; Mana, G.

2014-01-01

In a watt balance, stray capacitances exist between the coil and the magnet. Since the electric current flowing in the coil creates a difference in electric potentials between the coil and magnet, their electrostatic interactions must be taken into account. This paper reports the results of a fin......In a watt balance, stray capacitances exist between the coil and the magnet. Since the electric current flowing in the coil creates a difference in electric potentials between the coil and magnet, their electrostatic interactions must be taken into account. This paper reports the results...

The impact of microwave stray radiation to in-vessel diagnostic components

Energy Technology Data Exchange (ETDEWEB)

Hirsch, M.; Laqua, H. P.; Hathiramani, D.; Baldzuhn, J.; Biedermann, C.; Cardella, A.; Erckmann, V.; König, R.; Köppen, M.; Zhang, D. [Max-Planck-Institut für Plasmaphysik, Teilinstitut Greifswald, EURATOM Association, D-17489 Greifswald (Germany); Oosterbeek, J.; Brand, H. von der; Parquay, S. [Technische Universiteit Eindhoven, department Technische Natuurkunde, working group for Plasma Physics and Radiation Technology, Den Doelch 2, 5612 AZ Eindhoven (Netherlands); Jimenez, R. [Centro de Investigationes Energeticas, Medioambientales y Technológicas, Association EURATOM/CIEMAT, Avenida Complutense 22, Madrid 28040 (Spain); Collaboration: W7-X Teasm

2014-08-21

Microwave stray radiation resulting from unabsorbed multiple reflected ECRH / ECCD beams may cause severe heating of microwave absorbing in-vessel components such as gaskets, bellows, windows, ceramics and cable insulations. In view of long-pulse operation of WENDELSTEIN-7X the MIcrowave STray RAdiation Launch facility, MISTRAL, allows to test in-vessel components in the environment of isotropic 140 GHz microwave radiation at power load of up to 50 kW/m{sup 2} over 30 min. The results show that both, sufficient microwave shielding measures and cooling of all components are mandatory. If shielding/cooling measures of in-vessel diagnostic components are not efficient enough, the level of stray radiation may be (locally) reduced by dedicated absorbing ceramic coatings on cooled structures.

Stray current monitoring at Nuremberg subway; Streustromueberwachung bei der U-Bahn Nuernberg

Energy Technology Data Exchange (ETDEWEB)

Altmann, M.; Halfmann, U.; Schneider, E. [Siemens AG, Erlangen (Germany). TS EL EN 2; Roesch, N. [VAG Verkehrs-AG Nuernberg, FA/SA - Starkstromanlagen, Nuernberg (Germany)

2004-05-01

Operating DC traction systems requires protective measures against the effects of stray currents. Damage by corrosion could occur both at railway and third party installations. The continuous effectiveness of protective measures needs to be monitored and recorded during revenue operation, and shall be capable to be demonstrated to supervising authorities. Measuring the rail-to-earth potential within the traction network under operational conditions, combined with centralized analysis, visualization, signaling and archiving is a straightforward and efficient method of stray current monitoring. For more than one year, the stray current monitoring system SITRAS SMS {sup registered} has been undergoing successful field application at the Nuremberg Subway. (orig.)

A degradation model for stray current induced corrosion in underground reinforced concrete structures

NARCIS (Netherlands)

Polder, R.B.; Peelen, W.H.A.

2003-01-01

This paper describes the effects of stray currents on durability and reinforcement corrosion of underground concrete structures. Cathodic protection of underground pipelines are stationary sources of stray current interference with concrete, and rail traction systems are non-stationary sources. The

Electrolytic corrosion of water pipeline system in the remote distance from stray currents—Case study

Directory of Open Access Journals (Sweden)

Krzysztof Zakowski​

2016-06-01

Full Text Available Case study of corrosion failure of urban water supply system caused by the harmful effects of stray currents was presented. The failure occurred at a site distant from the sources of these currents namely the tramway and railway traction systems. Diagnosis revealed the stray currents flow to pipeline over a remote distance of 800/1000 m from the point of failure. At the point of failure stray currents flowed from the pipeline to the ground through external insulation defects, causing the process of electrolytic corrosion of the metal. Long distance between the affected section of the pipeline and the sources of stray currents excludes the typical protection against stray currents in the form of electrical polarized drainage. Corrosion protection at this point can be achieved by using the earthing electrodes made of magnesium, which will also provide cathodic current protection as galvanic anode.

A survey of gastrointestinal helminth of stray dogs in Zabol city, southeastern of Iran

Directory of Open Access Journals (Sweden)

Geraili, A.

2016-03-01

Full Text Available Canids are reservoir for some zoonoses helminthic disease. They are one of main public health problem. The aim of this study was to ascertain frequency of gastrointestinal helminthic infection of stray dogs in Zabol city, southeaster of Iran. In this descriptive study, 30 stray dogs were euthanized, intestine was removed by necropsy. Then, the intestines was opened by scalpel and their contents passed through mesh sieve. The helminth were collected. The nematodes were preserved in 70% ethanol with 5% glycerin and cestodes were preserved in 70% ethanol. The cestodes were stained by acetocarmine. The nematodes were cleared by lactophenol. The genus and species of helminth were identified by identification keys. Twenty two (73.3% of stray dogs had at least one intestinal helminthic infection. Recovered helminth from stray dogs include: Taenia hydatigena (53.3%, Taenia ovis (20%, Taenia multiceps (6.6%, Mesocestoides spp (10%, Toxocara canis (23.3%, Toxocara cati (3.3%. Data showed that the stray dogs in Zabol city harbor some important zoonoses helminth parasite like Toxocara.

Stray-electron accumulation and effects in HIF accelerators

International Nuclear Information System (INIS)

Cohen, R.H.; Friedman, A.; Furman, M.A.; Lund, S.M.; Molvik, A.W.; Stoltz, P.; Vay, J.-L.

2003-01-01

Stray electrons can be introduced in positive-charge accelerators for heavy ion fusion (or other applications) as a result of ionization of ambient gas or gas released from walls due to halo-ion impact, or as a result of secondary-electron emission. Electron accumulation is impacted by the ion beam potential, accelerating fields, multipole magnetic fields used for beam focus, and the pulse duration. We highlight the distinguishing features of heavy-ion accelerators as they relate to stray-electron issues, and present first results from a sequence of simulations to characterize the electron cloud that follows from realistic ion distributions. Also, we present ion simulations with prescribed random electron distributions, undertaken to begin to quantify the effects of electrons on ion beam quality

[Scattered light and glare sensitivity after wavefront-guided photorefractive keratectomy (WFG-PRK) and laser in situ keratomileusis (WFG-LASIK)].

Science.gov (United States)

Vignal, R; Tanzer, D; Brunstetter, T; Schallhorn, S

2008-05-01

To compare glare sensitivity measured by the intraocular scattered light between WFG-PRK and WFG-LASIK at 12 months follow-up and to assess its correlation to patients' complaints. Prospective and randomized study on 13 patients treated with WFG-LASIK, 13 patients with WFG-PRK and a control group of 35 patients. The intraocular stray light was measured by the Oculus C-Quant 12 months after surgery and before surgery for the control group. Photopic and mesopic contrast acuity and glare symptoms were reported pre- and postoperatively. Stray light values were normal in 79% of patients after WFG-LASIK and PRK and 86% in the control group, with mean values of 1.05 log, 1.03 log, and 0.99 log, respectively (p>0.05). All the patients with significant glare complaints had impaired stray light values versus 31.5% in the no-complaint group. Photopic and mesopic contrast acuity and glare symptoms were improved 1 year after surgery compared to preoperatively (no significant difference between groups). WFG-LASIK and PRK are safe and equivalent procedures regarding quality of vision. The measurement of stray light can be a discriminative test to assessing patients' glare complaints.

Experimental observations of stray current effects on steel fibres embedded in mortar

DEFF Research Database (Denmark)

Solgaard, A.O.S.; Carsana, M.; Geiker, M.R.

2013-01-01

It is known that stray direct current can cause corrosive damage over time to bar reinforced concrete, but knowledge on the consequences to steel fibre reinforced concrete is limited. This paper presents analyses and corresponding results from an experimental program (parametric study) investigat......It is known that stray direct current can cause corrosive damage over time to bar reinforced concrete, but knowledge on the consequences to steel fibre reinforced concrete is limited. This paper presents analyses and corresponding results from an experimental program (parametric study......) investigating the conditions required for current to be picked up by embedded steel fibres or reinforcement (rebars). The experiments showed that there is a clear ‘length effect’ related to the susceptibility of stray current being picked up by embedded steel (fibres or rebars): the shorter the reinforcement...

Stray dog and cat laws and enforcement in Czech Republic and in Italy

Directory of Open Access Journals (Sweden)

Eva Voslářvá

2012-01-01

Full Text Available The growing numbers of stray dogs and cats have posed serious public-health, socioeconomic, political and animal-welfare problems in many EU countries. Stray animal population control is a complex issue and there are no easy solutions. Recognising the importance of the issue the European Commission has, since 2007, actively contributed to the elaboration of the first global welfare standards for the control of dog populations in the framework of the World Organisation for Animal Health (OIE. Problem-solving approaches vary in different countries as there is no common European Community legislation dealing with stray animal control. In this paper the authors describe the characteristics of the stray dog and cat problem in general and focus on existing European legislation. A comparative overview of policies and measures in place in the Czech Republic and in Italy is made to observe the differences between the two countries and understand the different needs in each, considering their historical and social differences (i.e. a post-communist eastern country vs a western country and founder member of what is now the European Union.

Searching for O-X-B mode-conversion window with monitoring of stray microwave radiation in LHD

International Nuclear Information System (INIS)

Igami, H.; Kubo, S.; Laqua, H. P.; Nagasaki, K.; Inagaki, S.; Notake, T.; Shimozuma, T.; Yoshimura, Y.; Mutoh, T.; LHD Experimental Group

2006-01-01

In the Large Helical Device, the stray microwave radiation is monitored by using so-called sniffer probes during electron cyclotron heating. In monitoring the stray radiation, we changed the microwave beam injection angle and search the O-X-B mode-conversion window to excite electron Bernstein waves (EBWs). When the microwave beam is injected toward the vicinity of the predicted O-X-B mode-conversion window, the electron temperature rises in the central part of overdense plasmas. In that case, the stray radiation level near the injection antenna becomes low. These results indicate that monitoring the stray radiation near the injection antenna is helpful in confirming the effectiveness of excitation of EBWs simply without precise analysis

FACT light collection - solid light concentrators in Cherenkov Astronomy

Energy Technology Data Exchange (ETDEWEB)

Braun, Isabel [ETH Zurich, Institute for Particle Physics, CH-8093 Zurich (Switzerland); Collaboration: FACT-Collaboration

2011-07-01

Pixelized cameras of Imaging Atmospheric Cherenkov Telescopes use hollow light guides with reflective surfaces based on the Winston cone design. These cones minimize insensitive spaces between the photo sensors and shield the camera from stray background light by limiting the angular acceptance to the primary reflector area. FACT (First G-APD Cherenkov Telescope) will be the first IACT with Geiger-mode avalanche photodiodes as light sensors. Solid light concentrators complementing these sensors will be used instead of hollow Winston cones. We will present simulations and measurements of our light collector design, which was optimized for the requirements of the FACT telescope and detector, and discuss the specific differences to more traditional solutions.

Seroepidemiological survey of helminthic parasites of stray dogs in Sari City, northern Iran.

Science.gov (United States)

Gholami, Ishirzad; Daryani, Ahmad; Sharif, Mehdi; Amouei, Afsaneh; Mobedi, Iraj

2011-01-15

The objective of this study was to determine the prevalence rate of helminthic parasites in stray dogs' population especially zoonotic infections and to identify potential risk factors in the different areas of Sari city in Caspian area, north of Iran. During the period from April to September 2007, 50 stray dogs were collected from urban areas of Sari city. Recovered parasites were fixed in alcohol and stained by carmine then observed by microscope. The taxonomic study was carried out by measuring different parts of the body of helminthes and statistical tests were performed using the Chi-square test. A total of 27 adult and 23 juvenile stray dogs were collected and the overall prevalence rate of infection was 90%. The three most common helminthes were Toxocara canis (60%), Ancylostoma caninum (46%) and Dipylidium caninum (36%). Other parasites were Uncinaria stenocephala (12%), Taenia hydatigena (6%), Spirocerca lupi (6%), Dirofilaria immitis (6%), Toxascaris leonina (2%), Rictularia sp. (2%), Taenia ovis (2%) and Taenia taeniformis (2%). Five species of zoonotic helminthes recovered were T. canis, A. caninum, U. stenocephala, D. caninum and D. immitis. Hookworm infections (58%) were more common significantly in the young stray dogs (p caninum, T. canis and U. stenocephala, there was significant difference between juvenile and adult dogs (p < 0.05). The results highlight the potential role of stray dogs for transmission of helminthic parasites particularly zoonotic parasites that are a significant risk to human health.

WIDESPREAD OF STRAY DOGS: METHODS FOR SOLVING THE PROBLEM IN CERTAIN REGIONS OF BOSNIA AND HERZEGOVINA

OpenAIRE

Muhamed Katica; Nedzad Gradascevic; Nejra Hadzimusic; Zarema Obradovic; Ramo Mujkanovic; Esad Mestric; Senad Coloman; Muhamed Dupovac

2017-01-01

Stray dogs are the ones not microchipped, which live across the streets and other public surfaces unattended, and so represent a serious public-health problem. Lack of human support for the stray dogs causes a range of problems - from territorial status to ensuring food. Such conditions force them to activate a self-preservation mechanism and return to natural behavioral patterns. Regarding the fact that several thousands of stray dogs were recorded in observed regions of Bosnia and Herze...

Monitoring millimeter wave stray radiation during ECRH operation at ASDEX Upgrade

Science.gov (United States)

Schubert, M.; Honecker, F.; Monaco, F.; Schmid-Lorch, D.; Schütz, H.; Stober, J.; Wagner, D.

2012-09-01

Due to imperfection of the single path absorption, ECRH at ASDEX Upgrade (AUG) is always accompanied by stray radiation in the vacuum vessel. New ECRH scenarios with O2 and X3 heating schemes extend the operational space, but they have also the potential to increase the level of stray radiation. There are hazards for invessel components. Damage on electric cables has already been encountered. It is therefore necessary to monitor and control the ECRH with respect to the stray radiation level. At AUG a system of Sniffer antennas equipped with microwave detection diodes is installed. The system is part of the ECRH interlock circuit. We notice, however, that during plasma operation the variations of the Sniffer antenna signal are very large. In laboratory measurements we see variations of up to 20 dB in the directional sensitivity and we conclude that an interference pattern is formed inside the copper sphere of the antenna. When ECRH is in plasma operation at AUG, the plasma is acting as a phase and mode mixer for the millimeter waves and thus the interference pattern inside the sphere changes with the characteristic time of the plasma dynamics. In order to overcome the difficulty of a calibrated measurement of the average stray radiation level, we installed bolometer and pyroelectric detectors, which intrinsically average over interference structures due to their large active area. The bolometer provides a robust calibration but with moderate temporal resolution. The pyroelectric detector provides high sensitivity and a good temporal resolution, but it raises issues of possible signal drifts in long pulses.

Monitoring millimeter wave stray radiation during ECRH operation at ASDEX Upgrade

Directory of Open Access Journals (Sweden)

Wagner D.

2012-09-01

Full Text Available Due to imperfection of the single path absorption, ECRH at ASDEX Upgrade (AUG is always accompanied by stray radiation in the vacuum vessel. New ECRH scenarios with O2 and X3 heating schemes extend the operational space, but they have also the potential to increase the level of stray radiation. There are hazards for invessel components. Damage on electric cables has already been encountered. It is therefore necessary to monitor and control the ECRH with respect to the stray radiation level. At AUG a system of Sniffer antennas equipped with microwave detection diodes is installed. The system is part of the ECRH interlock circuit. We notice, however, that during plasma operation the variations of the Sniffer antenna signal are very large. In laboratory measurements we see variations of up to 20 dB in the directional sensitivity and we conclude that an interference pattern is formed inside the copper sphere of the antenna. When ECRH is in plasma operation at AUG, the plasma is acting as a phase and mode mixer for the millimeter waves and thus the interference pattern inside the sphere changes with the characteristic time of the plasma dynamics. In order to overcome the difficulty of a calibrated measurement of the average stray radiation level, we installed bolometer and pyroelectric detectors, which intrinsically average over interference structures due to their large active area. The bolometer provides a robust calibration but with moderate temporal resolution. The pyroelectric detector provides high sensitivity and a good temporal resolution, but it raises issues of possible signal drifts in long pulses.

Simplified magnetic circuit for the calculation of the stray magnetic flux through the shell gaps

Energy Technology Data Exchange (ETDEWEB)

Collarin, P.; Piovan, R. [Associazioni EURATOM-ENEA-CNR-Univ. di Padova (Italy). Gruppo di Padova per Ricerche sulla Fusione

1995-12-31

Significant toroidal magnetic field perturbations, stray flux at the shell gaps and current mismatching in the coils of the toroidal field winding are measured during the start-up and the flat-top phases of RFX. These phenomena are consistent with large and wall locked MHD modes: at first some m = 1 modes evolve separately one after the other, afterwards they concur to a wide and localized plasma perturbation that persists during the flat-top. These perturbations are heavily influenced by the stray magnetic flux through the shell gaps. Hence a magnetic circuit that mainly considers the magnetic reluctance of the conducting shell gaps has been developed in order to estimate this stray flux and, therefore, to evaluate the stabilizing capability of the shell. The observation of the MHD modes, the description of the equivalent magnetic network, the estimation of the stray flux and the comparison with the experimental measurements are reported in the paper.

Simplified magnetic circuit for the calculation of the stray magnetic flux through the shell gaps

International Nuclear Information System (INIS)

Collarin, P.; Piovan, R.

1995-01-01

Significant toroidal magnetic field perturbations, stray flux at the shell gaps and current mismatching in the coils of the toroidal field winding are measured during the start-up and the flat-top phases of RFX. These phenomena are consistent with large and wall locked MHD modes: at first some m = 1 modes evolve separately one after the other, afterwards they concur to a wide and localized plasma perturbation that persists during the flat-top. These perturbations are heavily influenced by the stray magnetic flux through the shell gaps. Hence a magnetic circuit that mainly considers the magnetic reluctance of the conducting shell gaps has been developed in order to estimate this stray flux and, therefore, to evaluate the stabilizing capability of the shell. The observation of the MHD modes, the description of the equivalent magnetic network, the estimation of the stray flux and the comparison with the experimental measurements are reported in the paper

Seroprevalence of Ehrlichia canis infection in stray dogs from Serbia

Directory of Open Access Journals (Sweden)

Nataša Bogićević

2017-03-01

Full Text Available Canine Monocytic Ehrlichiosis is a zoonotic bacterial disease with worldwide distribution. With regards to the population of stray dogs, the disease is facilitated due to their lifestyle and the lack of anti-parasitic protection. The aim of this study was to provide serological data on the presence of a specific Ehrlichia canis IgG antibodies in stray dogs, originating from 7 municipalities in Serbia. During the period from April 2013 to June 2014, 217 canine sera were submitted to the laboratory of the Department of Infectious Diseases of Animals and Bees, Faculty of Veterinary Medicine in Belgrade. An immunofluorescent antibody test (IFAT was performed to detect antibodies to Ehrlichia canis (cut off, 1:50. Seropositive dogs were found in 5 out of 7 counties with a seroprevalence varying from 3.57% to 20% and an overall seroprevalence of 11.06% (24/217. There was no statistically significant difference between the prevalence of infection and the host age or gender. Results showed that stray dogs contribute to maintaining and spreading of Ehrlichia canis in Serbia. Due to the close relationship between people and dogs, it is of great importance to constantly monitor and improve prevention of this disease.

PCR-Based Molecular Characterization of Toxocara spp. Using Feces of Stray Cats: A Study from Southwest Iran

OpenAIRE

Khademvatan, Shahram; Rahim, Fakher; Tavalla, Mahdi; Abdizadeh, Rahman; Hashemitabar, Mahmoud

2013-01-01

Feces of stray cat are potential sources of gastrointestinal parasites and play a crucial role in spreading and transmitting parasite eggs, larvae, and oocysts through contamination of soil, food, or water. In this study, we investigated the prevalence of Toxocara spp. infection in stray cats in Ahvaz city, southwest Iran. Eggs of Toxocara spp. in feces of stray cats were detected by the sucrose flotation method, and identification was conducted by polymerase chain reaction (PCR) and DNA sequ...

Convergence of highly parallel stray field calculation using the fast multipole method on irregular meshes

Science.gov (United States)

Palmesi, P.; Abert, C.; Bruckner, F.; Suess, D.

2018-05-01

Fast stray field calculation is commonly considered of great importance for micromagnetic simulations, since it is the most time consuming part of the simulation. The Fast Multipole Method (FMM) has displayed linear O(N) parallelization behavior on many cores. This article investigates the error of a recent FMM approach approximating sources using linear—instead of constant—finite elements in the singular integral for calculating the stray field and the corresponding potential. After measuring performance in an earlier manuscript, this manuscript investigates the convergence of the relative L2 error for several FMM simulation parameters. Various scenarios either calculating the stray field directly or via potential are discussed.

A study on protozoan infections (Giardia, Entamoeba, Isoapora and Cryptosporidium in stray dogs in Ilam province

Directory of Open Access Journals (Sweden)

S Kakekhani

2011-11-01

Full Text Available Giardia, Entamoeba, Isospora and Cryptosporidium are important protozoan parastites that caused diarrhea in human and animals. In the present study, fecal samples were collected fresh, directly from the rectum of 112 stray dogs in Ilam province. Giardia and Entamoeba were concentrated by using the formalin ether sedimentation method followed by the trichrome and iodine staining technique andCryptosporidium  oocysts  were  concentrated  by  using  the  formalin  ether  sedimentation  method  followed by the modified Ziehl-Neelsen staining technique. Of 112 stray dogs, protozoan infections were detected from feces of 46 dogs (41.07% that Giardia infection was detected from feces of 21 dogs (18.75%, Isospora 17 (15.17%, Cryptosporidium 8 (7.14% and synchronization infection to 2 protozoan in 9 dogs (8.03% and to 3 protozoan in 3 (2.67%. In the present study not observed to Entamoeba. No statistically significant differences in prevalence of protozoan parasites occurred between female (34.21 % and male (55.5 % stray dogs (p>0/05. But statistically significant differences in prevalence occurred between 1≥0 and 0 ≥1 stray dogs (p>0/05. So that stray dogs of Ilam province can cause infection of human water and food sources.

Internal stray radiation measurement for cryogenic infrared imaging systems using a spherical mirror.

Science.gov (United States)

Tian, Qijie; Chang, Songtao; He, Fengyun; Li, Zhou; Qiao, Yanfeng

2017-06-10

Internal stray radiation is a key factor that influences infrared imaging systems, and its suppression level is an important criterion to evaluate system performance, especially for cryogenic infrared imaging systems, which are highly sensitive to thermal sources. In order to achieve accurate measurement for internal stray radiation, an approach is proposed, which is based on radiometric calibration using a spherical mirror. First of all, the theory of spherical mirror design is introduced. Then, the calibration formula considering the integration time is presented. Following this, the details regarding the measurement method are presented. By placing a spherical mirror in front of the infrared detector, the influence of internal factors of the detector on system output can be obtained. According to the calibration results of the infrared imaging system, the output caused by internal stray radiation can be acquired. Finally, several experiments are performed in a chamber with controllable inside temperatures to validate the theory proposed in this paper. Experimental results show that the measurement results are in good accordance with the theoretical analysis, and demonstrate that the proposed theories are valid and can be employed in practical applications. The proposed method can achieve accurate measurement for internal stray radiation at arbitrary integration time and ambient temperatures. The measurement result can be used to evaluate whether the suppression level meets the system requirement.

It’s a Dog’s Life: International Tourists’ Perceptions of the Stray Dog Population of Bhutan.

Directory of Open Access Journals (Sweden)

Paul C Strickland

2015-12-01

Full Text Available This study investigates the international tourists’ perception of the stray dog population of Bhutan as little or no mention of the increasing stray dog population and their impact on tourism has been documented. After personally visiting the Kingdom on many occasions, it is evident that the stray dog population is increasing in dog numbers in major cities. The problems arising are negative comments by tourists relating to the stray dog population that are starting to appear in social media that may impact the visitor experience and the perception of Bhutan’s tourism industry. Veterinary science is aware of both increasing dog populations and the control of diseases such as Rabies however the author can find no evidence regarding challenges for the tourism industry. The problem is aided by no local veterinary clinics, no laws regarding dog governance, little funding for sterilization programs and being predominately a Buddhist country that cannot ‘cull’ animals. Using qualitative analysis from international tourist focus groups who were visiting Bhutan, this study highlights the perceptions of tourists regarding the stray dog population and how it may impact on visitor expectations. The paper suggests options that local government, Bhutanese nationals and visitors can do to assist the issue based on visitor feedback. Future research may include comparisons with other cities or countries to examine if it is a global issue or unique to Bhutan.

Identification of Zoonotic Parasites isolated from Stray Dogs in Bojnurd County Located in North-East of Iran

Directory of Open Access Journals (Sweden)

Kourosh Arzamani

2016-10-01

Full Text Available Dog can represent as an important source of zoonotic disease and important health problem for human. They can carry dangerous parasitic diseases such as hydatidosis, toxocariasis and Coenurus cerebralis to humans and animals. This study was performed in order to determine the prevalence and intensity of zoonotic parasites among stray dogs from Bojnurd, the capital city of North Khorasan province in North West of Iran. During a program performing by Bojnurd municipal on the slow killing of stray dogs, 32 dogs from Jun 2013 till March 2015 were selected. At necropsy their alimentary canals were removed and to identify the species of helminthes, the nematodes were cleared in lactophenol and cestodes were stained using carmine acid. Intestinal protozoan parasites were detected with parasitological methods. 28 (87.5% of 32 stray dogs infected at least with one helminth. Seven species of cestodes were isolated from examined dogs and three species of nematode were detected. Giardia sp. and Cryptosporidium sp. detected from fecal samples. This is the first study of the prevalence of intestinal zoonotic parasites in dogs in this area. It seems control of bearing stray dogs can help human health and reduction economic losses caused by stray dog’s zoonotic parasites.

Bartonella and Toxoplasma Infections in Stray Cats from Iraq

Science.gov (United States)

Switzer, Alexandra D.; McMillan-Cole, Audrey C.; Kasten, Rickie W.; Stuckey, Matthew J.; Kass, Philip H.; Chomel, Bruno B.

2013-01-01

Because of overpopulation, stray/feral cats were captured on military bases in Iraq as part of the US Army Zoonotic Disease Surveillance Program. Blood samples were collected from 207 cats, mainly in Baghdad but also in North and West Iraq, to determine the prevalence of Bartonella and Toxoplasma infections. Nine (4.3%) cats, all from Baghdad, were bacteremic with B. henselae type I. Seroprevalence was 30.4% for T. gondii, 15% for B. henselae, and 12.6% for B. clarridgeiae. Differences in Bartonella prevalence by location were statistically significant, because most of the seropositive cats were from Baghdad. There was no association between T. gondii seropositivity and either of the two Bartonella species surveyed. This report is the first report on the prevalence of Bartonella and T. gondii among stray cats in Iraq, which allows for better evaluation of the zoonotic risk potential to the Iraqi people and deployed military personnel by feral cat colonies. PMID:24062480

Problems Associated with the Microchip Data of Stray Dogs and Cats Entering RSPCA Queensland Shelters

Science.gov (United States)

Lancaster, Emily; Rand, Jacquie; Collecott, Sheila; Paterson, Mandy

2015-01-01

Simple Summary Microchip identification has become an important tool to reunite stray dogs and cats with their owners, and is now compulsory in most states of Australia. Improvement of the microchipping system in Australia is limited by a lack of published Australian data documenting the problems experienced by shelter staff when using microchip data to contact the owner of a stray animal. In this study we determine the character and frequency of inaccurate microchip data to identify weaknesses in the current microchipping system. This information could be used to develop strategies that increase the accuracy of microchip data that will increase the reclaiming of stray animals. Abstract A lack of published information documenting problems with the microchip data for the reclaiming of stray animals entering Australian shelters limits improvement of the current microchipping system. A retrospective study analysing admission data for stray, adult dogs (n = 7258) and cats (n = 6950) entering the Royal Society for the Prevention of Cruelty to Animals (RSPCA) Queensland between January 2012 and December 2013 was undertaken to determine the character and frequency of microchip data problems and their impact on outcome for the animal. Only 28% of dogs and 9% of cats were microchipped, and a substantial proportion (37%) had problems with their data, including being registered to a previous owner or organisation (47%), all phone numbers incorrect/disconnected (29%), and the microchip not registered (14%). A higher proportion of owners could be contacted when the microchip had no problems, compared to those with problems (dogs, 93% vs. 70%; cats, 75% vs. 41%). The proportion of animals reclaimed declined significantly between microchipped animals with no data problems, microchipped animals with data problems and non-microchipped animals—87%, 69%, and 37%, respectively, for dogs and 61%, 33%, and 5%, respectively, for cats. Strategies are needed to increase the accuracy of

Feline immunodeficiency virus testing in stray, feral, and client-owned cats of Ottawa

OpenAIRE

Little, Susan E.

2005-01-01

Feline immunodeficiency virus (FIV) seroprevalence is evaluated in 3 groups of cats. Seventy-four unowned urban strays were tested, as well as 20 cats from a small feral cat colony, and 152 client-owned cats. Of the 246 cats tested, 161 (65%) were male and 85 (35%) were female. Seroprevalence for FIV was 23% in the urban strays, 5% in the feral cat colony, and 5.9% in the client-owned cats. Ten cats (4%) were also positive for Feline leukemia virus (FeLV) antigen, including 2 cats coinfected ...

Stray current vs anodic polarization in reinforced mortar: a comparative study on steel corrosion behaviour in both regimes

NARCIS (Netherlands)

Chen, Zhipei; Koleva, D.A.; van Breugel, K.

2015-01-01

Stray current arising from direct current electrified traction systems and then circulat-ing in reinforced concrete structures may initiate corrosion or even accelerate existing corrosion processes on embedded reinforcement. Therefore, stray-current induced corrosion of nearby reinforced concrete

Residual stress characterization of steel TIG welds by neutron diffraction and by residual magnetic stray field mappings

Energy Technology Data Exchange (ETDEWEB)

Stegemann, Robert, E-mail: Robert.Stegemann@bam.de [Bundesanstalt für Materialforschung und -prüfung (BAM), Unter den Eichen 87, 12200 Berlin (Germany); Cabeza, Sandra; Lyamkin, Viktor; Bruno, Giovanni; Pittner, Andreas [Bundesanstalt für Materialforschung und -prüfung (BAM), Unter den Eichen 87, 12200 Berlin (Germany); Wimpory, Robert; Boin, Mirko [HZB Helmholtz-Zentrum Berlin, Hahn-Meitner-Platz 1, 14109 Berlin (Germany); Kreutzbruck, Marc [Bundesanstalt für Materialforschung und -prüfung (BAM), Unter den Eichen 87, 12200 Berlin (Germany); IKT, University of Stuttgart, Pfaffenwaldring 32, 70569 Stuttgart (Germany)

2017-03-15

The residual stress distribution of tungsten inert gas welded S235JRC+C plates was determined by means of neutron diffraction (ND). Large longitudinal residual stresses with maxima around 600 MPa were found. With these results as reference, the evaluation of residual stress with high spatial resolution GMR (giant magneto resistance) sensors was discussed. The experiments performed indicate a correlation between changes in residual stresses (ND) and the normal component of local residual magnetic stray fields (GMR). Spatial variations in the magnetic field strength perpendicular to the welds are in the order of the magnetic field of the earth. - Highlights: • Comparison of magnetic microstructure with neutron diffraction stress analysis. • High spatial resolution magnetic stray field images of hypereutectoid TIG welds. • Spatial variations of the stray fields are below the magnetic field of the earth. • GMR spin valve gradiometer arrays adapted for the evaluation of magnetic microstructures. • Magnetic stray fields are closely linked to microstructure of the material.

Study of Intestinal Helminthes of Stray Dogs and Thir Public Heath Importance in Hamadan City

Directory of Open Access Journals (Sweden)

Kh. Rahmati

2016-11-01

Full Text Available Introduction: Intestinal helminthesof dogs are a serious threat to human health and may cause dangerous diseases such as: hydatidosis and visceral larva migrans, that which cause severe complications in human. Th aim of this study was to determine the prevalenceof intestinal helminthes of stray dogs in Hamadan city, Iran.. Methods: A total of 103 stray dogswere shot in the inner and around of the city in year 2015. Following necropsy, the intestines' contents of dogs were examined for helminthes macroscopically. Thn, the collected worms, aftr washing with saline,were counted and identifid according to being Nematode, Cestodeor Acantcephala. Thn, collected Nematodes were put in glass containers containing 70% ethanol-glycerine and Cestodes aftr processing on slides were put in the 10% formalin. To identify the species of helminthes, the Cestodes were stained using carmine acid and Nematodes were cleared in lacto-phenol. Results: Result indicated that, 74(71.8%stray dogs were infected at least by one species of intestinal helminthes. Th species of parasites were as follows: Echinococcus granulosus 37.9%, Dipylidium caninum 51.5%, Toxocara canis 19.4%, Taenia hydatigena 24.3%, T. multiceps 2.9%, T. ovis 1.9%, Mesocest oideslineatus 4.9%, and Acantho cephala 5.8%. Thre was no association between insex, season and region with prevalence of intestinal helminthes (P 0.05 between the prevalence of intestinal helminthes and dogs' age. Conclusions: Ths study indicatesd that,infection rate of helminthes in stray dogs is washigh in Hamadan city. Thse parasites are important in terms of human health and economic aspects. Threfore, it is more essential that public health authoritiesto develop control strategies for stray dogs population.

Gastrointestinal parasites in stray and shelter cats in the municipality of Rio de Janeiro, Brazil

Directory of Open Access Journals (Sweden)

Pâmela Figueiredo Pereira

Full Text Available Abstract The increasingly urban nature of the population has led many people to choose independent pets, such as cats. This situation has also made it possible for these animals to be abandoned, thus increasing the numbers of cats on the streets and in shelters. These animals can act as a source of infection for other hosts. Between 2014 and 2015, the frequency of gastrointestinal parasites in captive and stray cats in the municipality of Rio de Janeiro was analyzed. Ninety-one fecal samples were collected from captive cats and 172 from stray cats. Centrifugal sedimentation and flotation techniques were used. The frequency of parasites among the stray cats was 77.3%, and this was significantly higher than the frequency observed in captive cats (49.5%. Helminths were detected more frequently, and hookworms were the parasites most detected. Toxocara cati, Cystoisospora sp. and Dipylidium caninum were also detected. No statistical difference in the frequency of parasites was observed between the sexes among the captive cats. However, among the stray cats, males (85.5% presented higher positivity than females (71.8%. The high frequency of hookworms, which are the agent for “cutaneous larva migrans” in humans, shows the need to control parasitic infections among the cats studied.

PCR-based molecular characterization of Toxocara spp. using feces of stray cats: a study from Southwest Iran.

Science.gov (United States)

Khademvatan, Shahram; Rahim, Fakher; Tavalla, Mahdi; Abdizadeh, Rahman; Hashemitabar, Mahmoud

2013-01-01

Feces of stray cat are potential sources of gastrointestinal parasites and play a crucial role in spreading and transmitting parasite eggs, larvae, and oocysts through contamination of soil, food, or water. In this study, we investigated the prevalence of Toxocara spp. infection in stray cats in Ahvaz city, southwest Iran. Eggs of Toxocara spp. in feces of stray cats were detected by the sucrose flotation method, and identification was conducted by polymerase chain reaction (PCR) and DNA sequencing. Of the 140 fecal samples that were randomly collected from public environments during the months of January to May 2012, 45% were found to harbour Toxocara spp. eggs. The highest prevalence of Toxocara spp. eggs was found in the central area of Ahvaz city (28.6%). T. canis eggs were found in 4 (6.34%) of the 63 positive samples. Stray cats are found in parks, playgrounds, and other public places and may be a potential contamination risk. Identification of Toxocara spp. using molecular methods is sufficiently sensitive to detect low levels of parasites and identify the different Toxocara spp. in feces. The relatively high prevalence of Toxocara spp. infection may continue to increase due to lack of effective environmental hygiene control in Iran. Consequently, there is a need to plan adequate programs to detect, identify, and control this infection as well as stray cats in the region.

PCR-based molecular characterization of Toxocara spp. using feces of stray cats: a study from Southwest Iran.

Directory of Open Access Journals (Sweden)

Shahram Khademvatan

Full Text Available Feces of stray cat are potential sources of gastrointestinal parasites and play a crucial role in spreading and transmitting parasite eggs, larvae, and oocysts through contamination of soil, food, or water. In this study, we investigated the prevalence of Toxocara spp. infection in stray cats in Ahvaz city, southwest Iran. Eggs of Toxocara spp. in feces of stray cats were detected by the sucrose flotation method, and identification was conducted by polymerase chain reaction (PCR and DNA sequencing. Of the 140 fecal samples that were randomly collected from public environments during the months of January to May 2012, 45% were found to harbour Toxocara spp. eggs. The highest prevalence of Toxocara spp. eggs was found in the central area of Ahvaz city (28.6%. T. canis eggs were found in 4 (6.34% of the 63 positive samples. Stray cats are found in parks, playgrounds, and other public places and may be a potential contamination risk. Identification of Toxocara spp. using molecular methods is sufficiently sensitive to detect low levels of parasites and identify the different Toxocara spp. in feces. The relatively high prevalence of Toxocara spp. infection may continue to increase due to lack of effective environmental hygiene control in Iran. Consequently, there is a need to plan adequate programs to detect, identify, and control this infection as well as stray cats in the region.

A review on stray current-induced steel corrosion in infrastructure

NARCIS (Netherlands)

Chen, Zhipei; Koleva, D.A.; van Breugel, K.

2017-01-01

Metallic corrosion can cause substantial damage at various levels and in almost all types of infrastructure. For metallic corrosion to occur, a certain external environment and the presence of corrodents are the prerequisites. Stray current-induced corrosion, however, is a rather underestimated

Experimental Study on the Influence of AC Stray Current on the Cathodic Protection of Buried Pipe

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Qingmiao Ding

2016-01-01

Full Text Available The size of the damaged area of the coating and its position on the pipeline impacted the cathodic protection potential, and there was a damaged area of the greatest impact value. When damaged area was 300 mm2, the IR drop was the largest, and this situation could easily lead to inadequate protection; when the parallel spacing between pipeline and interference source was unchanged, the measured value curves of cathodic protection potential presented “U” shaped trend with the increasing stray current interference intensity. Under certain parallel spacing between pipeline and interference source, high alternating stray current intensity would cause serious negative offsets, so that the overprotection of the pipeline occurred, and make the coating crack; there was a parallel threshold length. When less than the threshold, the pipe-ground potential increases rapidly with the parallel length increasing. In order to judge whether a pipeline was interference by AC stray current and the risk of stray current corrosion, we should make a comprehensive analysis of the cathodic protection energizing potential, the switch-off potential, AC pipe-soil potential, IR drops, and so on.

What's in a name? Perceptions of stray and feral cat welfare and control in Aotearoa, New Zealand.

Science.gov (United States)

Farnworth, Mark J; Campbell, Joanna; Adams, Nigel J

2011-01-01

New Zealanders (n = 354) rated the acceptability of lethal and nonlethal cat control methods and the importance of conservation and welfare. Lethal control was more acceptable for feral cats than strays; for nonlethal control, the inverse was true. More than concern for the welfare of cats subjected to control, perceived conservation benefits, risk of disease transfer, and companion cat welfare dictated the acceptability of control measures. Similarly, the welfare consideration for groups of cats differed, transitioning from companion (highest) to feral (lowest). Differences in attitudes toward acceptability of control methods were evident. In particular, nonhuman animal professionals ranked lethal control as more acceptable than did nonanimal professionals. Cat caregivers (owners) considered both conservation and welfare issues of greater importance than did nonowners. Owners ranked the acceptability of nonlethal control methods higher for stray cats, but not feral, than did nonowners. This research indicates that the use of the terms stray and feral may have significant impact on cats in New Zealand. There is also a greater consideration of conservation values than of welfare in stray and feral cat control.

Molecular detection of blood pathogens and their impacts on levels of packed cell volume in stray dogs from Thailand

Directory of Open Access Journals (Sweden)

Supawadee Piratae

2017-04-01

Full Text Available Objective: To evaluate the prevalence of blood parasite infection in stray dogs by PCR technique and the association between levels of packed cell volume (PCV and blood parasitic infection in stray dogs. Methods: A total of 65 blood samples were collected from stray dogs in animal quarantine station from Mahasarakham, Thailand to evaluate the levels of PCV before molecular screening for tick-borne pathogens infection. Results: Stray dogs were positive with one or more pathogens in 44 (67.69% out of 65 blood samples. Ehrlichia canis [43.1%, 95% confidence interval (CI: 38.1–48.1] was the most common blood pathogen found infecting in stray dogs in Mahasarakham Province, followed by Anaplasma platys (29.2%, 95% CI: 24.2–34.2, Hepatozoon canis (12.3%, 95% CI: 7.3–17.3 and Babesia canis vogeli (6.2%, 95% CI: 1.2–11.2, respectively. Moreover, co-infections with two pathogens were identified in 11 (16.9% of dogs examined and two (2.9% dogs were coinfections with three pathogens. Statistically significant relationship between the PCV levels and Ehrlichia canis infection was found (P < 0.05. Conclusions: This study indicated that blood pathogens are spreading in stray dogs and they are potentially high risk of agent transmission to human via exposure with tick vectors. It was also the first report of Anaplasma platys infection in dogs in north-eastern part of Thailand.

Detection of Helminth Eggs and Identification of Hookworm Species in Stray Cats, Dogs and Soil from Klang Valley, Malaysia.

Science.gov (United States)

Tun, Sandee; Ithoi, Init; Mahmud, Rohela; Samsudin, Nur Izyan; Kek Heng, Chua; Ling, Lau Yee

2015-01-01

The present study was conducted to determine the prevalence of helminth eggs excreted in the faeces of stray cats, dogs and in soil samples. A total of 505 fresh samples of faeces (from 227 dogs and 152 cats) and soil were collected. The egg stage was detected via microscopy after the application of formalin-ether concentration technique. Genomic DNA was extracted from the samples containing hookworm eggs and used for further identification to the species level using real-time polymerase chain reaction coupled with high resolution melting analysis. Microscopic observation showed that the overall prevalence of helminth eggs among stray cats and dogs was 75.7% (95% CI = 71.2%-79.9%), in which 87.7% of dogs and 57.9% of cats were infected with at least one parasite genus. Five genera of heliminth eggs were detected in the faecal samples, including hookworms (46.4%), Toxocara (11.1%), Trichuris (8.4%), Spirometra (7.4%) and Ascaris (2.4%). The prevalence of helminth infections among stray dogs was significantly higher than that among stray cats (p dog hookworm, Ancylostoma caninum, was also detected among cats, which is the first such occurrence reported in Malaysia till date. This finding indicated that there was a cross-infection of A. caninum between stray cats and dogs because of their coexistent within human communities. Taken together, these data suggest the potential role of stray cats and dogs as being the main sources of environmental contamination as well as for human infections.

Counteracting Animal Homelessness and Providing Care for Stray Animals as a Task of a Commune

OpenAIRE

Szalewska, Małgorzata

2017-01-01

The analysis of Polish binding law acts allows one to assume that, on normative level, the obligation of public administration to provide care for stray animals is deeply embedded. Both the Animal Protection Act, as well as the Act on Maintaining Cleanliness, indicate the tasks of a commune in the scope of providing care for stray animals, catching homeless animals and counteracting their homelessness. Simultaneously, the analysis of jurisdiction, and inquiries as well as considerations emerg...

Stray dog meat consumption and rabies | Wiwanitkit | African Health ...

African Journals Online (AJOL)

Stray dog meat consumption and rabies. V Wiwanitkit. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/ahs.v14i3.41 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

Individual monitoring in high-energy stray radiation fields

International Nuclear Information System (INIS)

Hoefert, M.; Stevenson, G.R.

1995-01-01

Due to the lack of passive or active devices that could be considered as personal dosemeters in high-energy stray fields one can at present only perform individual monitoring around high energy accelerators. Of all detectors currently available it is shown that the NTA film is the most suitable method for individually monitoring the neutron exposure of more than 3000 persons regularly, reliably, and cost effectively like at CERN. (author)

White light coronagraph in OSO-7

International Nuclear Information System (INIS)

Koomen, M.J.; Detwiler, C.R.; Brueckner, G.E.; Cooper, H.W.; Tousey, R.

1975-01-01

A small, externally occulted Lyot-type coronagraph, designated for use in the seventh unmanned Orbiting Solar Observatory (OSO-7), is described. Optical configuration, suppression of stray light, SEC vidicon detector, and data system are discussed, as well as integration of the instrument into the spacecraft and operation in orbit. Orbital operation produced daily images of the white light corona, from 2.8 to 10 solar radii, at least once per day for 2 3/4 yr. The first records of white light coronal transient events were obtained, and the corona was shown to be constantly changing

Optimization method of star tracker orientation for sun-synchronous orbit based on space light distribution.

Science.gov (United States)

Wang, Geng; Xing, Fei; Wei, Minsong; Sun, Ting; You, Zheng

2017-05-20

Star trackers, optical attitude sensors with high precision, are susceptible to space light from the Sun and the Earth albedo. Until now, research in this field has lacked systematic analysis. In this paper, we propose an installation orientation method for a star tracker onboard sun-synchronous-orbit spacecraft and analyze the space light distribution by transforming the complicated relative motion among the Sun, Earth, and the satellite to the body coordinate system of the satellite. Meanwhile, the boundary-curve equations of the areas exposed to the stray light from the Sun and the Earth albedo were calculated by the coordinate-transformation matrix under different maneuver attitudes, and the installation orientation of the star tracker was optimized based on the boundary equations instead of the traditional iterative simulation method. The simulation and verification experiment indicate that this installation orientation method is effective and precise and can provide a reference for the installation of sun-synchronous orbit star trackers free from the stray light.

Controlling stray electric fields on an atom chip for experiments on Rydberg atoms

Science.gov (United States)

Davtyan, D.; Machluf, S.; Soudijn, M. L.; Naber, J. B.; van Druten, N. J.; van Linden van den Heuvell, H. B.; Spreeuw, R. J. C.

2018-02-01

Experiments handling Rydberg atoms near surfaces must necessarily deal with the high sensitivity of Rydberg atoms to (stray) electric fields that typically emanate from adsorbates on the surface. We demonstrate a method to modify and reduce the stray electric field by changing the adsorbate distribution. We use one of the Rydberg excitation lasers to locally affect the adsorbed dipole distribution. By adjusting the averaged exposure time we change the strength (with the minimal value less than 0.2 V /cm at 78 μ m from the chip) and even the sign of the perpendicular field component. This technique is a useful tool for experiments handling Rydberg atoms near surfaces, including atom chips.

Feline immunodeficiency virus testing in stray, feral, and client-owned cats of Ottawa.

Science.gov (United States)

Little, Susan E

2005-10-01

Feline immunodeficiency virus (FIV) seroprevalence is evaluated in 3 groups of cats. Seventy-four unowned urban strays were tested, as well as 20 cats from a small feral cat colony, and 152 client-owned cats. Of the 246 cats tested, 161 (65%) were male and 85 (35%) were female. Seroprevalence for FIV was 23% in the urban strays, 5% in the feral cat colony, and 5.9% in the client-owned cats. Ten cats (4%) were also positive for Feline leukemia virus (FeLV) antigen, including 2 cats coinfected with FeLV and FIV. Seroprevalence for FIV in cats from Ottawa is similar to that found in other nonrandom studies of cats in North America.

Measurement of stray EC radiation on W7-AS

Science.gov (United States)

Gandini, F.; Hirsch, M.; Cirant, S.; Erckmann, V.; Granucci, G.; Kasparek, W.; Laqua, H. P.; Muzzini, V.; Nowak, S.; Radau, S.

2001-10-01

In the framework of a collaboration between IFP-CNR Milano, IPP Garching/Greifswald and IPF Stuttgart, a set of four millimeterwave probes has been installed in W7-AS stellarator at selected positions of the inner vessel wall. Their purpose is to observe RF stray radiation during operation in presence of strong level of Electron Cyclotron (EC) waves, used for plasma start-up, heating and current drive. The aim of these measurements is to benchmark two complementary theoretical models for the distribution of the stray radiation in the vessel. From these codes, quantitative predictions are expected for the spatial distribution of the RF wall load and the RF-impact on in-vessel components in large future devices such as W7-X and, possibly, ITER. This input is important to optimize the wall armour and select rf-compatible in-vessel materials. We present first measurements from different heating and startup scenarios, with up to 800 kW of injected power at 140 GHz and different launching geometries. An analysis of measurements performed on FTU using a previous version of sniffer probe is also presented.

Measurement of stray EC radiation on W7-AS

International Nuclear Information System (INIS)

Gandini, F.; Cirant, S.; Granucci, G.; Muzzini, V.; Nowak, S.; Hirsch, M.; Erckmann, V.; Laqua, H.P.; Radau, S.; Kasparek, W.

2001-01-01

In the framework of a collaboration between IFP-CNR Milano, IPP Garching/Greifswald and IPF Stuttgart, a set of four millimeterwave probes has been installed in W7-AS stellarator at selected positions of the inner vessel wall. Their purpose is to observe RF stray radiation during operation in presence of strong level of Electron Cyclotron (EC) waves, used for plasma start-up, heating and current drive. The aim of these measurements is to benchmark two complementary theoretical models for the distribution of the stray radiation in the vessel. From these codes, quantitative predictions are expected for the spatial distribution of the RF wall load and the RF-impact on in-vessel components in large future devices such as W7-X and, possibly, ITER. This input is important to optimize the wall armour and select rf-compatible in-vessel materials. We present first measurements from different heating and startup scenarios, with up to 800 kW of injected power at 140 GHz and different launching geometries. An analysis of measurements performed on FTU using a previous version of sniffer probe is also presented

Prevalence of intestinal helminth parasites in stray dogs in urban ...

African Journals Online (AJOL)

A total of 246 faecal samples were collected between October 2015 to February 2016, 154 from stray dogs in Harare and 92 from rural dogs in Arcturas, Goromonzi and Christon Bank. The samples were examined by flotation and sedimentation methods and helminth eggs identified and EPG counted. Of the 246 samples, ...

UV Blocking Glass: Low Cost Filters for Visible Light Photocatalytic Assessment

OpenAIRE

Dunnill, Charles W.

2014-01-01

A number of commercially available art protection products have been compared and assessed for their suitability as UV blocking filters in the application of “visible light” photocatalytic research. Many groups claiming visible light photocatalytic success employ filters to block out stray UV radiation in order to justify that their photocatalysts are indeed visible light photocatalysts and not UV light photocatalysts. These filters come in varying degrees of ability and price and many author...

MRI-related static magnetic stray fields and postural body sway: a double-blind randomized crossover study.

Science.gov (United States)

van Nierop, Lotte E; Slottje, Pauline; Kingma, Herman; Kromhout, Hans

2013-07-01

We assessed postural body sway performance after exposure to movement induced time-varying magnetic fields in the static magnetic stray field in front of a 7 Tesla (T) magnetic resonance imaging scanner. Using a double blind randomized crossover design, 30 healthy volunteers performed two balance tasks (i.e., standing with eyes closed and feet in parallel and then in tandem position) after standardized head movements in a sham, low exposure (on average 0.24 T static magnetic stray field and 0.49 T·s(-1) time-varying magnetic field) and high exposure condition (0.37 T and 0.70 T·s(-1)). Personal exposure to static magnetic stray fields and time-varying magnetic fields was measured with a personal dosimeter. Postural body sway was expressed in sway path, area, and velocity. Mixed-effects model regression analysis showed that postural body sway in the parallel task was negatively affected (P < 0.05) by exposure on all three measures. The tandem task revealed the same trend, but did not reach statistical significance. Further studies are needed to investigate the possibility of independent or synergetic effects of static magnetic stray field and time-varying magnetic field exposure. In addition, practical safety implications of these findings, e.g., for surgeons and others working near magnetic resonance imaging scanners need to be investigated. Copyright © 2012 Wiley Periodicals, Inc.

Detection of Helminth Eggs and Identification of Hookworm Species in Stray Cats, Dogs and Soil from Klang Valley, Malaysia.

Directory of Open Access Journals (Sweden)

Sandee Tun

Full Text Available The present study was conducted to determine the prevalence of helminth eggs excreted in the faeces of stray cats, dogs and in soil samples. A total of 505 fresh samples of faeces (from 227 dogs and 152 cats and soil were collected. The egg stage was detected via microscopy after the application of formalin-ether concentration technique. Genomic DNA was extracted from the samples containing hookworm eggs and used for further identification to the species level using real-time polymerase chain reaction coupled with high resolution melting analysis. Microscopic observation showed that the overall prevalence of helminth eggs among stray cats and dogs was 75.7% (95% CI = 71.2%-79.9%, in which 87.7% of dogs and 57.9% of cats were infected with at least one parasite genus. Five genera of heliminth eggs were detected in the faecal samples, including hookworms (46.4%, Toxocara (11.1%, Trichuris (8.4%, Spirometra (7.4% and Ascaris (2.4%. The prevalence of helminth infections among stray dogs was significantly higher than that among stray cats (p < 0.001. Only three genera of helminths were detected in soil samples with the prevalence of 23% (95% CI = 15.1%-31%, consisting of hookworms (16.6%, Ascaris (4% and Toxocara (2.4%. The molecular identification of hookworm species revealed that Ancylostoma ceylanicum was dominant in both faecal and soil samples. The dog hookworm, Ancylostoma caninum, was also detected among cats, which is the first such occurrence reported in Malaysia till date. This finding indicated that there was a cross-infection of A. caninum between stray cats and dogs because of their coexistent within human communities. Taken together, these data suggest the potential role of stray cats and dogs as being the main sources of environmental contamination as well as for human infections.

PENGARUH PEMBELAJARAN KOOPERATIF TWO STAY TWO STRAY BERPENDEKAT AN SETS TERHADAP HASIL BELAJAR KIMIA SISWA SMA NEGERI 1 COMAL

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A. T. Setiawan

2016-07-01

Full Text Available Penelitian ini bertujuan untuk mengetahui pengaruh pembelajaran kooperatif two stay two stray berpendekatan SETS terhadap hasil belajar siswa. Desain eksperimen yang digunakan dalam penelitian ini adalah quasi experimental design. Hasil penelitian menunjukkan bahwa pembelajaran kooperatif two stay two stray berpendekatan SETS berpengaruh signitikan terhadap hasil belajar pada materi pokok teori asam basa dengan kontribusi koefisien determinasi sebesar 25%. Selain itu, pembelajaran juga mencapai ketuntasan belajar klasikal sebesar 37 dari 43 siswa, sehingga pembelajaran tersebut termasuk efektif.This study aimed to determine the effect of two stay two stray cooperative learning with SETS approach on student learning outcomes. Experimental design used in this study is a quasi experimental design. The results showed that two stay two stray cooperative learning with SETS approach have a significant effect on learning outcomes in acid-base theory of the subject matter with the contribution of the determination coefficient of 25%. In addition, the study also achieved mastery learning classical by 37 of the 43 students, so that it includes effective learning.

Rejection Sensitivity Moderates the Impact of Rejection on Self-Concept Clarity

Science.gov (United States)

Ayduk, Özlem; Gyurak, Anett; Luerssen, Anna

2014-01-01

Self-concept clarity (SCC) refers to the extent to which self-knowledge is clearly and confidently defined, internally consistent, and temporally stable. Research shows that SCC can be undermined by failures in valued goal domains. Because preventing rejection is an important self-relevant goal for people high in rejection sensitivity (RS), it is hypothesized here that failures to attain this goal would cause them to experience diminished SCC. Study 1, an experimental study, showed that high-RS people’s SCC was undermined following rejection but not following an aversive experience unrelated to rejection. Study 2, a daily diary study of couples in relationships, used occurrence of partner conflicts to operationalize rejection. Replicating the findings in Study 1, having a conflict on any given diary day predicted a greater reduction in the SCC of high- compared to low-RS people on the following day. The implications for understanding the conditions under which rejection negatively affects the self-concept are discussed. PMID:19713567

Gastrointestinal Helminths and Ectoparasites in the Stray Cats (Felidae: Felis catus) of Ahar Municipality, Northwestern Iran

Science.gov (United States)

YAKHCHALI, Mohammad; HAJIPOUR, Nasser; MALEKZADEH-VIAYEH, Reza; ESMAEILNEJAD, Bijan; NEMATI-HARAVANI, Taher; FATHOLLAHZADEH, Mohammad; JAFARI, Rasool

2017-01-01

Background: The stray cats are considered as the sources of emerging humans and domestic livestock pathogens and the zoonoses of public health importance. The present study was aimed to elucidate intestinal helminth infections and infestation with ectoparasites of the stray cats of Ahar City, northwestern Iran. Methods: Totally, 51 stray cats were randomly trapped from different parts of the city between Mar and Nov 2013. The cats were assessed for ectoparasites by hair brushing, skin scraping, acetate tape preparation and othic swabs. They were euthanized and inspected for helminths infection. Results: Overall prevalence of helminths and flea were 44/51 (86.3%) and 31/51 (60.78%), respectively. The infection rates were significantly different among different age groups (PDipylidium caninum (29.41%), T. hydatigena (19.6%)) were identified. The predominant infectious helminths in all the infected cats were T. cati (86.3% with egg per gram of feces 27.75±9). Of the 270 collected fleas, two species of Ctenocephalides felis (80%) and C. canis (20%) were notably frequent in the cats aged 2-3-year-old. The average number of fleas per each infected cat was recorded as 5.29, with no incidence of cross-infection. Conclusion: The results indicated the high rate of helminths infections and flea infestation in the urban stray cats of which Toxocara cati and Ctenocephalides felis may play important roles as zoonotic agents in the region. PMID:28761492

Gastrointestinal helminth parasites of pet and stray dogs as a potential risk for human health in Bahir Dar town, north-western Ethiopia

Directory of Open Access Journals (Sweden)

Tadiwos Abere

Full Text Available Aim: A cross-sectional study was carried out from November 2011 to April 2012 to determine the prevalence and species of gastrointestinal (GI helminth parasites in pet and stray dogs as a potential risk for human health in Bahir Dar town, northwestern Ethiopia. Materials and Methods: A total of 384 and 46 faecal samples were collected from pet and stray dogs, respectively and xamined by using standard coprologic techniques. Results: The overall prevalence of GI helminth infection in pet and stray dogs was 75.26 and 84.78%, respectively. The detected parasites with their frequencies in pet dogs were Ancylostoma caninum (78.89%, Toxocara canis (39.79%, Dipylidium caninum (29.75%, Strongyloides stercoralis (29.06%, Taeniidae (23.87% and Trichuris vulpis (7.95%. Stray dogs were found more likely to be polyparasitized and presented higher prevalence of A. caninum, T. canis, S. stercoralis, Trichuris vulpis and Taeniidae (P < 0.05 than domiciled ones. Diphyllobothrium latum was detected only in 10.25% of stray dogs. Toxocara canis and A. caninum (P < 0.05 were detected more frequently in dogs with less than 6 months of age (P <0.05 than old age dogs. The sex or breed groups didn't significantly affect the prevalence of parasites. A significant variation was recorded (P < 0.05 between different feeding systems where higher prevalence was observed in uncontrolled feeding group (82.18% compared to controlled feeding (32.08%. Conclusion: Different gastrointestinal parasites in pet and stray dogs were identified in the study area that can potentially infect humans and cause serious public-health problems. Thus, concerted efforts should therefore be made to educate dog owners to embrace modern dog disease control programs and measures have to be taken on stray dogs. [Vet World 2013; 6(7.000: 388-392

THE SOCIETY’S PERCEPTION OF THE LIFE QUALITY AND POPULATION CONTROL OF STRAY DOGS

Directory of Open Access Journals (Sweden)

Flavio Fernando Batista Moutinho

2015-10-01

Full Text Available In most Brazilian municipalities there is an overpopulation of stray dogs, which causes problems to the urban order, the environment and the public health, in addition to mistreatment to these dogs. In such context we foresee the need of developing actions targeting the population control of these animals. This essay aims at knowing the perception of social actors, such as managers of entities responsible for control actions, managers of NGOs working with animal protection and population in general with respect to the life quality and population control of stray dogs. Questionnaires were used on samples of individuals of these three groups and the data thereof were analyzed with descriptive statistics techniques and frequency comparison. The results allowed us to conclude that the society’s perception of population control and life quality of these animals bear important differences under the viewpoint of the three evaluated groups; however, they also bear significant similarities, especially with respect to the perception of the responsibility for the development of population control actions, the acceptance of using public funds intended to public health in control actions, the classification of such population density as large and the poor life quality of these animals. population control, social perception, stray dog.,

FIR laser scattering and heterodyne receiver measurements on Alcator C

International Nuclear Information System (INIS)

Woskoboinikow, P.; Praddaude, H.C.; Mulligan, W.J.; Cohn, D.R.; Lax, B.

1982-01-01

The MIT program to develop high power collective Thomson scattering diagnostics is presented. The D 2 O laser Thomson scattering system is operational on Alcator C tokamak. The major components include a 0.5 MW, 150 ns D 2 O laser, a heterodyne receiver mixer, a 25 MW, 381 μ DCOOD laser local oscillator and X-band I.F. electronics including a 32 channel multiplexer filter centered at 9.4 GHz with 80 MHz wide channels. Initial scattering measurement showed high level of stray D 2 O laser power. The spectrum was obtained by operating the Thomson scattering diagnostics with no plasma in the tokamak. An X-band notch filter was placed after the Schottky diode mixer to reject a 240 MHz band centered at 9.4 GHz. The stray light level was reduced by 16 to 20 db. Other sources of background noise such as strong non-thermal scattering and ECE did not appear to be a problem. A gas filled cell was placed on the Alcator C scattering system to reduce the level of stray light. Work is underway to improve the transverse mode quality of the laser and receiver to improve matching to the beam and viewing dumps. (Kato, T.)

Effect of stray current on corrosion behavior of reinforcing steel: importance of cell geometry and orientation with respect to the electrical field

NARCIS (Netherlands)

Chen, Zhipei; Koleva, D.A.

2016-01-01

Stray current circulating in reinforced concrete structures may initiate corrosion or accelerate existing corrosion processes on embedded reinforcement. In some cases, the range of dangerous or unwanted interactions of stray currents under favorable conditions (environment), is much broader than is

IMPLEMENTASI MODEL PEMBELAJARAN TWO STAY TWO STRAY DALAM PEMBELAJARAN BERBASIS KEMAMPUAN BERPIKIR KRITIS KELAS V SD

Directory of Open Access Journals (Sweden)

M. Yusuf Setia Wardana

2017-04-01

Full Text Available Benefits of mathematics are to equip students with the ability to think logically, analytical, systematically, critically, and creatively, as well as the ability to cooperate. Based on observations in elementary school, there are 40% of students have not reached KKM and students have lack of critical abilities to understand math problems, and they have low activity of the study. One of models that can be applied is Two Stay Two Stray. The study used True Experimental Design with Posttest-Only Control Design. The population in this study was all fifth grade students of SD Negeri Semarang Rejosari 03. Data of critical thinking skills of the students in average on test of critical thinking skills mastery was 3.31 ≥ 2.67, it can be said to have a complete description. The conclusion is a model of Two Stay Two Stray being effective for critical thinking skills and mathematics learning outcomes of fifth grade students in SD Negeri Rejosari 03 Semarang. Keywords: two stay two stray model, critical thinking ability.

Lung allograft rejection in the rat. I. Accelerated rejection caused by graft lymphocytes

International Nuclear Information System (INIS)

Prop, J.; Nieuwenhuis, P.; Wildevuur, C.R.

1985-01-01

To find out to what extent rejection of lungs differs from that of other organs, functional rejection of lung allografts was studied in five combinations of inbred rat strains. Rejection could be monitored accurately by perfusion scintigraphy, and equally well by chest roentgenography. The rejection of lung grafts was found to proceed remarkably fast, when compared with heart grafts, in combinations with strong RT1-incompatibilities. This accelerated rejection pattern could be converted into rejection at a normal pace by pretreatment of the donor with 10 Gy roentgen irradiation one day before transplantation. Donor pretreatment depleted the lung graft's bronchus-associated lymphoid tissue (BALT) of lymphocytes. When grafts were depleted of all other passenger cells as well--by retransplantation from a cyclosporine-treated intermediate host--they showed an even more reduced immunogenicity, probably because of the loss of donor-type dendritic cells. These results indicate that lymphocytes from the BALT of lung grafts are capable of accelerating the rejection response

Light from electron avalanches and background rejection in X-ray astronomy

International Nuclear Information System (INIS)

Siegmund, O.H.W.; Sanford, P.W.; Mason, I.M.; Culhane, J.L.; Cockshott, R.

1980-01-01

A modified version of the parallel plate imaging proportional counter, developed to register images of cosmic x-ray sources in the focal planes of x-ray telescopes, has been constructed to investigate the application of risetime discrimination to the scintillation pulses caused by the electron avalanche process. It is shown that efficient background event rejection (> 90%) is achieved and the application of this system for x-ray astronomy is discussed. (U.K.)

Symptoms and Cognitive Effects of Exposure to Magnetic Stray Fields of MRI Scanners

NARCIS (Netherlands)

Vocht, Frank Gérard de

2006-01-01

People working routinely with magnetic resonance imaging (MRI) systems report a number of symptoms related to their presence in the inhomogeneous static magnetic fields (the stray field) surrounding these scanners. Experienced symptoms and neurobehavioral performance among engineers manufacturing

Stray cats are more frequently infected with zoonotic protists than pet cats.

Science.gov (United States)

Kvac, Martin; Hofmannova, Lada; Ortega, Ynes; Holubova, Nikola; Horcickova, Michaela; Kicia, Marta; Hlaskova, Lenka; Kvetonova, Dana; Sak, Bohumil; McEvoy, John

2017-12-06

Faecal samples were collected from cats kept as pets (n = 120) and stray cats (n = 135) in Central Europe (Czech Republic, Poland and Slovakia) and screened for the presence of Cryptosporidium spp., Giardia intestinalis (Kunstler, 1882), Encephalitozoon spp. and Enterocytozoon bieneusi Desportes, Le Charpentier, Galian, Bernard, Cochand-Priollet, Lavergne, Ravisse et Modigliani, 1985 by PCR analysis of the small-subunit of rRNA (Cryptosporidium spp. and G. intestinalis) and ITS (microsporidia) genes. Sequence analysis of targeted genes revealed the presence of C. felis Iseki, 1979, G. intestinalis assemblage F, E. cuniculi Levaditi, Nicolau et Schoen, 1923 genotype II, and E. bieneusi genotype D. There was no correlation between the occurrence of detected parasites and sex, presence of diarrhoea or drug treatment (drug containing pyrantel and praziquantel). Compared to pet cats (7%), stray cats (30%) were statistically more frequently infected with protist parasites and overall may present a greater risk to human health.

Stray Cats Gastrointestinal Parasites and its Association With Public Health in Ahvaz City, South Western of Iran

Science.gov (United States)

Khademvatan, Shahram; Abdizadeh, Rahman; Rahim, Fakher; Hashemitabar, Mahamoud; Ghasemi, Mohammad; Tavalla, Mahdi

2014-01-01

Background: Cats are the hosts for some zoonotic parasites such as Toxoplasma gondii and Toxocara spp. which are important in medicine and veterinary. Studies on the prevalence of intestinal parasites of cats have received little attention in south west of Iran. Objectives: The current study aimed to investigate the prevalence of parasites in stray cats in Ahvaz. Materials and Methods: Random sampling was carried out from January to May 2012. One hundred and forty fecal samples from stray cats were examined using sucrose flotation method. Results: Gastrointestinal parasites were found in 121 of the 140 (86.4%) examined samples. The parasites detected in stray cats were Toxocara spp. (45%, 63/140), Isospora spp. (21.4%, 30/140), nematode larvae (21.4%, 30/140), Taenia spp. (18.6%, 26/140), Sarcocystis spp. (17.1%, 24/140), Eimeria spp. (15%, 21/140), Blastocystis spp. (14.3%, 20/140), Giardia spp, (10.7%, 15/140), Physaloptera spp. (7.1%, 10/140), and amoeba cyst (5.7%, 8/140) respectively. The prevalence of infection by Joyexiella spp. and hook worms (4.3%, 6/140), for example, Dipylidium caninum (2.9%, 4/140) was similar; and the prevalence of infection by T. gondii and Dicrocoelium dendriticum was similar (1.4%, 2/140). Conclusions: Since the prevalence of zoonotic gastrointestinal parasites such as Toxocara spp. in stray cats is high, there is a need to plan adequate programs to control these zoonotic parasites. PMID:25485047

Stray dogs and cats as potential sources of soil contamination with zoonotic parasites

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Katarzyna Szwabe

2017-03-01

Cat faeces represent a more important potential source of environmental contamination with zoonotic parasites than dog faeces. Among the detected parasites of stray dogs and cats, Toxocara present an important zoonotic risk for the local human population, especially children.

Evaluation of stray radiofrequency radiation emitted by electrosurgical devices

International Nuclear Information System (INIS)

De Marco, M; Maggi, S

2006-01-01

Electrosurgery refers to the passage of a high-frequency, high-voltage electrical current through the body to achieve the desired surgical effects. At the same time, these procedures are accompanied by a general increase of the electromagnetic field in an operating room that may expose both patients and personnel to relatively high levels of radiofrequency radiation. In the first part of this study, we have taken into account the radiation emitted by different monopolar electrosurgical devices, evaluating the electromagnetic field strength delivered by an electrosurgical handle and straying from units and other electrosurgical accessories. As a summary, in the worst case a surgeon's hands are exposed to a continuous and pulsed RF wave whose magnetic field strength is 0.75 A m -1 (E-field 400 V m -1 ). Occasionally stray radiation may exceed ICNIRP's occupational exposure guidelines, especially close to the patient return plate. In the second part of this paper, we have analysed areas of particular concern to prevent electromagnetic interference with some life-support devices (ventilators and electrocardiographic devices), which have failed to operate correctly. Most clinically relevant interference occurred when an electrosurgery device was used within 0.3 m of medical equipment. In the appendix, we suggest some practical recommendations intended to minimize the potential for electromagnetic hazards due to therapeutic application of RF energy

Gastrointestinal and ectoparasites from urban stray dogs in Fortaleza (Brazil): high infection risk for humans?

Science.gov (United States)

Klimpel, Sven; Heukelbach, Jörg; Pothmann, David; Rückert, Sonja

2010-08-01

Dogs are important definite or reservoir hosts for zoonotic parasites. However, only few studies on the prevalence of intestinal parasites in urban areas in Brazil are available. We performed a comprehensive study on parasites of stray dogs in a Brazilian metropolitan area. We included 46 stray dogs caught in the urban areas of Fortaleza (northeast Brazil). After euthanization, dogs were autopsied. Ectoparasites were collected, and the intestinal content of dogs were examined for the presence of parasites. Faecal samples were collected and analysed using merthiolate iodine formaldehyde concentration method. A total of nine different parasite species were found, including five endoparasite (one protozoan, one cestode and three nematode species) and four ectoparasite species (two flea, one louse and one tick species). In the intestinal content, 3,162 specimens of four helminth species were found: Ancylostoma caninum (prevalence, 95.7%), Dipylidium caninum (45.7%), Toxocara canis (8.7%) and Trichuris vulpis (4.3%). A total of 394 ectoparasite specimens were identified, including Rhipicephalus sanguineus (prevalence, 100.0%), Heterodoxus spiniger (67.4%), Ctenocephalides canis (39.1%) and Ctenocephalides felis (17.4%). In the faeces, intestinal parasites were detected in 38 stray dogs (82.6%), including oocysts of Giardia sp. (2.2%) and eggs of the nematode A. caninum (82.6%). Neither eggs nor larval stages of D. caninum, T. canis or T. vulpis were detected in dog faeces. Sensitivity of faecal examination for A. caninum was 86.4% (95% confidence interval, 72.0-94.3) but zero percentage for the other intestinal helminth species. Our data show that stray dogs in northeast Brazil carry a multitude of zoonotic ecto- and endoparasites, posing a considerable risk for humans. With the exception of A. caninum, sensitivity of faecal examination was negligible.

Molecular detection of Ehrlichia canis, Hepatozoon canis and Babesia canis vogeli in stray dogs in Mahasarakham province, Thailand.

Science.gov (United States)

Piratae, Supawadee; Pimpjong, Kiattisak; Vaisusuk, Kotchaphon; Chatan, Wasupon

2015-01-01

Canine tick borne diseases showing distribution worldwide have caused morbidity and mortality in dogs. This study observed the mainly tick borne pathogens described for dogs in Thailand, Ehrlichia canis, Hepatozoon canis and Babesia canis vogeli. From May to July 2014, blood samples were collected from 79 stray dogs from 7 districts of Mahasarakham province to molecular surveyed for 16s rRNA gene of E. canis and 18s rRNA gene of H. canis and B. canis vogeli. Twenty eight (35.44%) of stray dogs showed the infection with tick borne pathogens. The prevalence of E. canis infection was the highest with 21.5% (17/79). DNA of H. canis and B. canis vogeli were detected at the prevalence of 10.1% (8/79) and 6.3% (5/79), respectively. Co-infection between E. canis and B. canis vogeli were identified in 2 (2.5%) dogs. The results indicated that a wide range of tick borne pathogens are circulation in the canine population in Mahasarakham province. This study is the first report on prevalence of E. canis, H. canis and B. canis vogeli in stray dogs in Mahasarakham, a province in northern part of Thailand. This data providing is important to understand the prevalence of E. canis, H. canis and B. canis vogeli infection in stray dogs in this region, which will assist in the management of these blood parasite.

An estimate of the radiation-induced cancer risk from the whole-body stray radiation exposure in neutron radiotherapy

International Nuclear Information System (INIS)

Geraci, J.P.; Jackson, K.L.; Mariano, M.S.

1982-01-01

1980 BEIR III risk factors have been used to estimate the secondary cancer risks from the whole-body stray radiation exposures occurring in neutron radiotherapy. Risks were calculated using linear, linear-quadratic and quadratic dose-response models for the gamma component of the stray radiation. The linear dose-response model was used to calculate risk for the neutron component of the stray radiation. These estimates take into consideration for the first time the age and sex distribution of patients undergoing neutron therapy. Changes in risk as a function of the RBE (10-100) assigned to the stray neutron radiation component have also been assessed. Excess risks in neutron-treated patients have been compared with excess risks for photon-treated patients and with the expected incidence of cancer in a normal population having the same age and sex distribution. Results indicate that it will be necessary to tolerate a higher incidence of secondary cancers in patients undergoing fast neutron therapy than is the case with conventional photon therapy. For neutron RBEs of less than 50 the increased risk is only a fraction of the normal expected incidence of cancer in this population. Comparison of the radiation-induced risk with reported normal tissue complication rates in the treatment volume indicates that the excess cancer risk is substantially lower than the risk from other late normal tissue effects. (author)

Shielding of the NBI boxes against W7-X magnetic stray fields

Energy Technology Data Exchange (ETDEWEB)

Kick, Manfred [Max-Planck-Institut fuer Plasmaphysik, Boltzmannstr. 2, D-85748 Garching (Germany)], E-mail: Kick@arcor.de; Sielanko, Juliusz [Maria Curie Sklodowska University, Pl. M. C. Sklodowskie 1, 20-031 Lublin (Poland); Heinemann, Bernd; Riedl, Rudolf; Speth, Eckehart; Staebler, Albrecht [Max-Planck-Institut fuer Plasmaphysik, Boltzmannstr. 2, D-85748 Garching (Germany)

2009-06-15

Neutral Beam Injection (NBI), besides ECRH, is foreseen as one of the main heating devices at the W7-X stellarator currently under construction at IPP Greifswald, Germany. In a final stage 20 MW of NBI heating power will be installed generated by two NBI boxes of the ASDEX Upgrade (AUG) type. Since magnetic fields generally affect the trajectories of charged particles, essentially all the NBI boxes - including ion sources, acceleration sections, neutralisers and deflection magnets - must be shielded against the stray fields of W7-X. In the magnetic stray fields of W7-X there exist significant radial and toroidal components whereas at tokamaks the vertical components are dominant. The power loads on the ion dump and the protecting structures of the deflecting magnets and the beam lines caused by residual beam ions, therefore, will be strongly different. Thus the shielding concept of AUG cannot simply be taken over, but must be carefully redesigned in order to remain below the critical power limits. New modelling calculations of the magnetic shielding, the ion trajectories and the resulting power loads have been carried out for the 'high iota' and 'low shear' experimental scenarios of W7-X. The fields taken for these calculations are modelled by averaging the calculated W7-X stray fields on the one hand, and by fields generated by two-hypothetical-planar coils perpendicular to the x-y plane, on the other hand. The shielding concept for W7-X mainly consist of iron plates in the outer side regions of the boxes and as little magnetic material as possible inside the boxes.

Anti-glare LED lamps with adjustable illumination light field.

Science.gov (United States)

Chen, Yung-Sheng; Lin, Chung-Yi; Yeh, Chun-Ming; Kuo, Chie-Tong; Hsu, Chih-Wei; Wang, Hsiang-Chen

2014-03-10

We introduce a type of LED light-gauge steel frame lamp with an adjustable illumination light field that does not require a diffusion plate. Base on the Monte Carlo ray tracing method, this lamp has a good glare rating (GR) of 17.5 at 3050 lm. Compared with the traditional LED light-gauge steel frame lamp (without diffusion plate), the new type has low GR. The adjustability of the illumination light field could improve the zebra effect caused by the inadequate illumination light field of the lamp. Meanwhile, we adopt the retinal image analysis to discuss the influence of GR on vision. High GR could reflect stray light on the retinal image, which will reduce vision clarity and hasten the feeling of eye fatigue.

Stray animal populations and public health in the South Mediterranean and the Middle East regions

Directory of Open Access Journals (Sweden)

Aristarhos Seimenis

2014-06-01

Full Text Available Uncontrolled urban growth in South Mediterranean and the Middle East regions involves city dwellers and stray animals (mainly dogs and cats creating a dense and downgraded environment, in which irregular street garbage collection disposes sufficient food for survival and proliferation of stray animals. Under such conditions serious public health hazards are expected due to the increase of animal bites, the multiplication of insects and rodents vectors of different viral, bacterial, fungal and parasitic agents to which humans are exposed. Traditional national stray animal eradication programs and occasional small animals' humane elimination campaigns are insufficient to avert human and veterinary health risks when not coupled with modern technologies. In such environments, multiple foci of emerging and re‑emerging zoonoses easily spread, i.e. rabies, hydatidosis, leishmaniasis and toxoplasmosis. Upgrading urban and peri-urban situations requires integrated/coordinated management programmes, in which public and animal health services as well as municipalities have a crucial role. Control and upgrading programmes should be flexible and able to adapt to the specific conditions of the given country/region. In this context, intersectoral/interprofessional collaborations and community participation are crucial for any national and regional development strategies. In this respect, a global approach considering both public health and socio-economic problems shows to be extremely adequate and effective.

Problems Associated with the Microchip Data of Stray Dogs and Cats Entering RSPCA Queensland Shelters

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Emily Lancaster

2015-05-01

Full Text Available A lack of published information documenting problems with the microchip data for the reclaiming of stray animals entering Australian shelters limits improvement of the current microchipping system. A retrospective study analysing admission data for stray, adult dogs (n = 7258 and cats (n = 6950 entering the Royal Society for the Prevention of Cruelty to Animals (RSPCA Queensland between January 2012 and December 2013 was undertaken to determine the character and frequency of microchip data problems and their impact on outcome for the animal. Only 28% of dogs and 9% of cats were microchipped, and a substantial proportion (37% had problems with their data, including being registered to a previous owner or organisation (47%, all phone numbers incorrect/disconnected (29%, and the microchip not registered (14%. A higher proportion of owners could be contacted when the microchip had no problems, compared to those with problems (dogs, 93% vs. 70%; cats, 75% vs. 41%. The proportion of animals reclaimed declined significantly between microchipped animals with no data problems, microchipped animals with data problems and non-microchipped animals—87%, 69%, and 37%, respectively, for dogs and 61%, 33%, and 5%, respectively, for cats. Strategies are needed to increase the accuracy of microchip data to facilitate the reclaiming of stray dogs and cats.

Gastrointestinal Helminths and Ectoparasites in the Stray Cats (Felidae: Felis catus of Ahar Municipality, Northwestern Iran

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Mohammad YAKHCHALI

2017-06-01

Full Text Available Background: The stray cats are considered as the sources of emerging humans and domestic livestock pathogens and the zoonoses of public health importance. The present study was aimed to elucidate intestinal helminth infections and infestation with ectoparasites of the stray cats of Ahar City, northwestern Iran.Methods: Totally, 51 stray cats were randomly trapped from different parts of the city between Mar and Nov 2013. The cats were assessed for ectoparasites by hair brushing, skin scraping, acetate tape preparation and othic swabs. They were euthanized and inspected for helminths infection.Results: Overall prevalence of helminths and flea were 44/51 (86.3% and 31/51 (60.78%, respectively. The infection rates were significantly different among different age groups (P<0.05. Of the 282 isolated helminths, three species of nematodes (Toxocara cati (86.3%, T. leonina (11.77%, Ancylostoma tubaeforme (5.9% and four species of cestodes (Taenia taeniaeformis (64.7%, Mesocestoides lineatus (49.02%, Dipylidium caninum (29.41%, T. hydatigena (19.6% were identified. The predominant infectious helminths in all the infected cats were T. cati (86.3% with egg per gram of feces 27.75±9. Of the 270 collected fleas, two species of Ctenocephalides felis (80% and C. canis (20% were notably frequent in the cats aged 2-3-year-old. The average number of fleas per each infected cat was recorded as 5.29, with no incidence of cross-infection.Conclusion: The results indicated the high rate of helminths infections and flea infestation in the urban stray cats of which Toxocara cati and Ctenocephalides felis may play important roles as zoonotic agents in the region.

Monitoring DC stray current interference of steel sheet pile structures in railway environment

NARCIS (Netherlands)

Peelen, W.H.A.; Neeft, E.A.C.; Leegwater, G.; Kanten-Roos, W. van; Courage, W.M.G.

2011-01-01

Steel structures near DC powered railways are expected to be affected by stray current interference. This causes accelerated corrosion rates. Therefore steel is often not used as a building material in these cases, although certain advantages over the alternative material concrete exist. These

Seroprevalence and Risk Factors Associated with Seropositivity to Toxoplasma gondii among Stray and Domestic Cats (Felis silvestris catus

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Christel Bohn T. Garcia

2014-12-01

Full Text Available Toxoplasma gondii is a protozoan parasite that causes toxoplasmosis. It is widespread in the environment and infects a variety of warm-blooded animals, causing miscarriages and birth problems. Previous studies in the Philippines have determined the seropositivity of T. gondii in humans. However, the seroprevalence of the parasite among household pets, par ticularly its feline def initive host, remains insufficient . This study aimed to: (1 determine the seroprevalence of T. gondii antibodies among domestic and stray cats in the Philippines; and, (2 to analyze the risk factors associated with seropositivity. Blood samples from 59 domestic and stray cats were collected and tested for T. gondii seropositivity using a commercially available indirect ELISA kit, while pet owners and handlers were given questionnaires about their cats. Thirteen or 22.03% of the cats were seropositive to T. gondii, and risk factor analysis revealed a significant difference between domestic and stray cats with regard to diet (p = 0.026, OR = 8.333, c = 0.299 and domestication (p = 0.039, OR = 5.000, c = 0.276. Cats fed with table food tested 31.43% seropositive compared to the 4.35% of those fed with cat food, whereas 33.33% of the stray cats were seropositive compared to 7.69% for domestic cats. Odds ratio test showed that the risk factors studied were associated with higher likelihood of T. gondii seropositivity. These results implicate diet and environment in the transmission dynamics of T. gondii among cats.

Trajectories of Italian Children's Peer Rejection: Associations with Aggression, Prosocial Behavior, Physical Attractiveness, and Adolescent Adjustment.

Science.gov (United States)

Di Giunta, Laura; Pastorelli, Concetta; Thartori, Eriona; Bombi, Anna Silvia; Baumgartner, Emma; Fabes, Richard A; Martin, Carol Lynn; Enders, Craig K

2017-12-08

In the present study, the predictors and outcomes associated with the trajectories of peer rejection were examined in a longitudinal sample of Italian children (338 boys, 269 girls) ages 10 to 14 years. Follow-up assessments included 60% of the original sample at age 16-17. Low, medium, and high rejection trajectory groups were identified using growth mixture models. Consistent with previous studies, we found that (a) being less prosocial and more physically aggressive at age 10 was characteristic of those children with the high rejection trajectory; (b) being less attractive was related to higher peer rejection from age 10 to 14; and (c) boys with a high rejection trajectory showed high levels of delinquency and anxiety-depression and low levels of academic aspiration at age 16-17, whereas girls with a high rejection trajectory showed low levels of academic aspiration and social competence at age 16-17. Our findings indicate the detrimental consequences of peer rejection on children's development and adjustment and shed light on the mechanisms that contribute to maintaining or worsening (e.g., being attractive, prosocial, and aggressive) a child's negative status (e.g., being rejected) within his or her peer group over time.

Rf Discharge Impedance Measurements Using a New Method to Determine the Stray Impedances

NARCIS (Netherlands)

Bakker, L.P.; Kroesen, G.M.W.; Hoog, de F.J.

1999-01-01

The impedance of a capacitively coupled radio frequency discharge in a tubular fluorescent lamp filled with neon and mercury is measured. The stray impedances in the electrical network are determined using a new method that requires no extra instruments. The reflection of power is used to determine

Decoding of digital magnetic recording with longitudinal magnetization of a tape from a magneto-optical image of stray fields

Science.gov (United States)

Lisovskii, F. V.; Mansvetova, E. G.

2017-05-01

For digital magnetic recording of encoded information with longitudinal magnetization of the tape, the connection between the domain structure of a storage medium and magneto-optical image of its stray fields obtained using a magnetic film with a perpendicular anisotropy and a large Faraday rotation has been studied. For two-frequency binary code without returning to zero, an algorithm is developed, that allows uniquely decoding of the information recorded on the tape based on analysis of an image of stray fields.

Matrix light and pixel light: optical system architecture and requirements to the light source

Science.gov (United States)

Spinger, Benno; Timinger, Andreas L.

2015-09-01

Modern Automotive headlamps enable improved functionality for more driving comfort and safety. Matrix or Pixel light headlamps are not restricted to either pure low beam functionality or pure high beam. Light in direction of oncoming traffic is selectively switched of, potential hazard can be marked via an isolated beam and the illumination on the road can even follow a bend. The optical architectures that enable these advanced functionalities are diverse. Electromechanical shutters and lens units moved by electric motors were the first ways to realize these systems. Switching multiple LED light sources is a more elegant and mechanically robust solution. While many basic functionalities can already be realized with a limited number of LEDs, an increasing number of pixels will lead to more driving comfort and better visibility. The required optical system needs not only to generate a desired beam distribution with a high angular dynamic, but also needs to guarantee minimal stray light and cross talk between the different pixels. The direct projection of the LED array via a lens is a simple but not very efficient optical system. We discuss different optical elements for pre-collimating the light with minimal cross talk and improved contrast between neighboring pixels. Depending on the selected optical system, we derive the basic light source requirements: luminance, surface area, contrast, flux and color homogeneity.

An epidemiological survey on intestinal helminths of stray dogs in Mashhad, North-east of Iran.

Science.gov (United States)

Emamapour, Seyed Rasoul; Borji, Hassan; Nagibi, Abolghasem

2015-06-01

This research was conducted to determine the prevalence of gastrointestinal helminths in stray dogs in the northeast of Iran, with special attention to those parasites that can be transmitted to human. In this experiment, a total of 72 adult and 18 juvenile stray dogs were collected and necropsied for the presence of helminth parasites from October 2011 to August 2012. The overall prevalence of gastrointestinal helminths was 86 % (95 % CI: 79.2-92.8 %). The observed helminths of the gastrointestinal tract were listed as follows: Toxocara canis (29 %), Toxascaris leonina (7 %), Ancylostoma caninum (2 %), Taenia hydatigena (43 %), Dipylidium caninum (39 %), Echinococcus granulosus (38 %), Mesocestoides lineatus (16 %), Taenia multiceps (11 %), Taenia ovis (3 %). There were no significant differences for the prevalence of gastrointestinal helminths between female (83.6 %) and male (89.7 %) and between young (89 %) and adult (72.2 %) animals. However, the prevalence of E. granulosus, T. hydatigena and D. caninum showed an increasing trend with increasing host age, significantly. Based on our data, it is important to point out the presence of zoonotic agents, namely E. granulosus and T. canis in stray dogs in the investigated area. Due to its impact on public health, appropriate control measures should be taken and it is recommended to determine the most appropriate preventive methods.

Experimental investigation of the ECRH stray radiation during the start-up phase in Wendelstein 7-X

Science.gov (United States)

Moseev, Dmitry; Laqua, Heinrich; Marsen, Stefan; Stange, Torsten; Braune, Harald; Erckmann, Volker; Gellert, Florian; Oosterbeek, Johann Wilhelm; Wenzel, Uwe

2017-07-01

Electron cyclotron resonance heating (ECRH) is the main heating mechanism in the Wendelstein 7-X stellarator (W7-X). W7-X is equipped with five absolutely calibrated sniffer probes that are installed in each of the five modules of the device. The sniffer probes monitor energy flux of unabsorbed ECRH radiation in the device and interlocks are fed with the sniffer probe signals. The stray radiation level in the device changes significantly during the start-up phase: plasma is a strong microwave absorber and during its formation the stray radiation level in sniffer probes reduces by more than 95%. In this paper, we discuss the influence of neutral gas pressure and gyrotron power on plasma breakdown processes.

Prevalence of Protozoa and Gastrointestinal Helminthes in Stray Cats in Zanjan Province, North-West of Iran

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SA Altome

2009-07-01

Full Text Available Background: Cats and other felines act as definitive hosts for many intestinal parasites, some of which are responsible for several zoonotic diseases.  The aim of this study was to determine the type and prevalence of protozoa and gastrointestinal helminthes among stray cats. Methods: A cross sectional study was conducted. Digestive tracts of 100 stray cats in Zanjan Province, north-west of Iran were autopsied in order to recognize gastrointestinal helminthes and intestinal protozoan parasites. These cats were collected by baited cage trapped from October 2007 to September 2008. Gender and species of helminthes and protozoa were rec­ognized using authentic diagnostic criteria. Statistical evaluation was performed by SPSS version 14. Results: Forty-two percent of cats were infected with intestinal protozoan parasites, 33% were infected with cestodes and 39% infected with gastrointestinal nematodes. Four species protozoan parasites and eight gastrointestinal helminthes were recovered from the animals, including Taenia taeniaeformis, Dipylidium spp., Joyeuxiella pasqaulei, Toxocara cati, Phy­saloptera praeputialis, Rectalaria spp., Onicolla, Cystoisospora spp., Toxoplasma gondii, and Sarcocystis spp . Conclusions: The high infection rate of Toxoplasma and some gastrointestinal helminthes in stray cats is considered to be critical from the viewpoint of public health importance.

Prevalence of zoonotic intestinal parasites in household and stray dogs in rural areas of Hamadan, Western Iran.

Science.gov (United States)

Sardarian, K; Maghsood, A H; Ghiasian, S A; Zahirnia, A H

2015-06-01

Zoonotic parasitic infections are a major global public and veterinary health problem and widespread among dogs. The objective of this study was to assess the prevalence of intestinal parasites in stray and household dogs in the rural areas of Hamadan district. During 2012, 1,500 fresh fecal samples from 243 household and 1,257 stray dogs were examined by using direct wet mount, simple zinc sulfate flotation, and Lugol's solution staining. Of 1,500 dogs, 20.4% were positive for intestinal parasites. Helminthes eggs were more frequently found in fecal samples than protozoan cysts or trophozoites (15.9% vs. 4.5%, respectively). Toxocara canis was the most frequently detected parasite, with a prevalence of 6.3%, followed by Taenia/Echinococcus spp. (2.9%), Isospora spp. (2.7%), and Toxascaris leonina (2.6%). Helminthes and protozoa were significantly more prevalent in household dogs than in stray dogs (Pparasites indicated that people residing in this area are at risk of exposure to these potentially hazardous zoonotic pathogens. Mass education of the general population is highly recommended to increase awareness of the potential for horizontal transmission of these parasitic infections from dogs to humans.

Understanding Rejection between First-and-Second-Grade Elementary Students through Reasons Expressed by Rejecters.

Science.gov (United States)

García Bacete, Francisco J; Carrero Planes, Virginia E; Marande Perrin, Ghislaine; Musitu Ochoa, Gonzalo

2017-01-01

Objective: The aim of this research was to obtain the views of young children regarding their reasons for rejecting a peer. Method: To achieve this goal, we conducted a qualitative study in the context of theory building research using an analysis methodology based on Grounded Theory. The collected information was extracted through semi-structured individual interviews from a sample of 853 children aged 6 from 13 urban public schools in Spain. Results: The children provided 3,009 rejection nominations and 2,934 reasons for disliking the rejected peers. Seven reason categories emerged from the analysis. Four categories refer to behaviors of the rejected children that have a cost for individual peers or peer group such as: direct aggression, disturbance of wellbeing, problematic social and school behaviors and dominance behaviors. A further two categories refer to the identities arising from the preferences and choices of rejected and rejecter children and their peers: personal identity expressed through preferences and disliking, and social identity expressed through outgroup prejudices. The "no-behavior or no-choice" reasons were covered by one category, unfamiliarity. In addition, three context categories were found indicating the participants (interpersonal-group), the impact (low-high), and the subjectivity (subjective-objective) of the reason. Conclusion: This study provides researchers and practitioners with a comprehensive taxonomy of reasons for rejection that contributes to enrich the theoretical knowledge and improve interventions for preventing and reducing peer rejection.

Clementine sensor suite

Energy Technology Data Exchange (ETDEWEB)

Ledebuhr, A.G. [Lawrence Livermore National Lab., CA (United States)

1994-11-15

LLNL designed and built the suite of six miniaturized light-weight space-qualified sensors utilized in the Clementine mission. A major goal of the Clementine program was to demonstrate technologies originally developed for Ballistic Missile Defense Organization Programs. These sensors were modified to gather data from the moon. This overview presents each of these sensors and some preliminary on-orbit performance estimates. The basic subsystems of these sensors include optical baffles to reject off-axis stray light, light-weight ruggedized optical systems, filter wheel assemblies, radiation tolerant focal plane arrays, radiation hardened control and readout electronics and low mass and power mechanical cryogenic coolers for the infrared sensors. Descriptions of each sensor type are given along with design specifications, photographs and on-orbit data collected.

Image rejects/retakes-radiographic challenges

International Nuclear Information System (INIS)

Waaler, D.; Hofmann, B.

2010-01-01

A general held position among radiological personnel prior to digitalisation was that the problem of image rejects/retakes should more or less vanish. However, rejects/retakes still impose several challenges within radiographic imaging; they occupy unnecessary resources, expose patients to unnecessary ionizing radiation and may also indicate suboptimal quality management. The latter is the main objective of this paper, which is based on a survey of international papers published both for screen/film and digital technology. The digital revolution in imaging seems to have reduced the percentage of image rejects/retakes from 10-15 to 3-5%. The major contribution to the decrease appears to be the dramatic reduction of incorrect exposures. At the same time, rejects/retakes due to lack of operator competence (positioning, etc.) are almost unchanged, or perhaps slightly increased (due to lack of proper technical competence, incorrect organ coding, etc.). However, the causes of rejects/retakes are in many cases defined and reported with reference to radiographers' subjective evaluations. Thus, unless radiographers share common views on image quality and acceptance criteria, objective measurements and assessments of reject/retake rates are challenging tasks. Interestingly, none of the investigated papers employs image quality parameters such as 'too much noise' as categories for rejects/retakes. Surprisingly, no reject/retake analysis seems yet to have been conducted for direct digital radiography departments. An increased percentage of rejects/retakes is related to 'digital skills' of radiographers and therefore points to areas for extended education and training. Furthermore, there is a need to investigate the inter subjectivity of radiographers' perception of, and attitude towards, both technical and clinical image quality criteria. Finally, there may be a need to validate whether reject/retake rate analysis is such an effective quality indicator as has been asserted

Image rejects/retakes--radiographic challenges.

Science.gov (United States)

Waaler, D; Hofmann, B

2010-01-01

A general held position among radiological personnel prior to digitalisation was that the problem of image rejects/retakes should more or less vanish. However, rejects/retakes still impose several challenges within radiographic imaging; they occupy unnecessary resources, expose patients to unnecessary ionizing radiation and may also indicate suboptimal quality management. The latter is the main objective of this paper, which is based on a survey of international papers published both for screen/film and digital technology. The digital revolution in imaging seems to have reduced the percentage of image rejects/retakes from 10-15 to 3-5 %. The major contribution to the decrease appears to be the dramatic reduction of incorrect exposures. At the same time, rejects/retakes due to lack of operator competence (positioning, etc.) are almost unchanged, or perhaps slightly increased (due to lack of proper technical competence, incorrect organ coding, etc.). However, the causes of rejects/retakes are in many cases defined and reported with reference to radiographers' subjective evaluations. Thus, unless radiographers share common views on image quality and acceptance criteria, objective measurements and assessments of reject/retake rates are challenging tasks. Interestingly, none of the investigated papers employs image quality parameters such as 'too much noise' as categories for rejects/retakes. Surprisingly, no reject/retake analysis seems yet to have been conducted for direct digital radiography departments. An increased percentage of rejects/retakes is related to 'digital skills' of radiographers and therefore points to areas for extended education and training. Furthermore, there is a need to investigate the inter-subjectivity of radiographers' perception of, and attitude towards, both technical and clinical image quality criteria. Finally, there may be a need to validate whether reject/retake rate analysis is such an effective quality indicator as has been asserted.

Generation of strong inhomogeneous stray fields by high-anisotropy permanent magnets

Energy Technology Data Exchange (ETDEWEB)

Samofalov, V.N. [National Technical University Kharkov Polytechnical Institute, 21 Frunze St., 61002 Kharkov (Ukraine)]. E-mail: samofalov@kpi.kharkov.ua; Ravlik, A.G. [National Technical University Kharkov Polytechnical Institute, 21 Frunze St., 61002 Kharkov (Ukraine); Belozorov, D.P. [National Scientific Center Kharkov Institute of Physics and Techonology, NAS of Ukraine, 1 Akademicheskaja St., 61108 Kharkov (Ukraine); Avramenko, B.A. [National Technical University Kharkov Polytechnical Institute, 21 Frunze St., 61002 Kharkov (Ukraine)

2004-10-01

Magnetic stray fields for systems of permanent magnets with high magnetic anisotropy are calculated and measured. It is shown that intensity of these fields exceeds value of an induction of a material of magnets in some time. Besides, these fields are characterized by high gradients, and size H-bar H can reach values up to10{sup 10}-10{sup 11}Oe{sup 2}/cm. Estimations of extremely achievable fields and their gradients are made.

Stray-field-induced Faraday contributions in wide-field Kerr microscopy and -magnetometry

International Nuclear Information System (INIS)

Markó, D.; Soldatov, I.; Tekielak, M.; Schäfer, R.

2015-01-01

The magnetic domain contrast in wide-field Kerr microscopy on bulk specimens can be substantially distorted by non-linear, field-dependent Faraday rotations in the objective lens that are caused by stray-field components emerging from the specimen. These Faraday contributions, which were detected by Kerr-magnetometry on grain-oriented iron–silicon steel samples, are thoroughly elaborated and characterized. They express themselves as a field-dependent gray-scale offset to the domain contrast and in highly distorted surface magnetization curves if optically measured in a wide field Kerr microscope. An experimental method to avoid such distortions is suggested. In the course of these studies, a low-permeability part in the surface magnetization loop of slightly misoriented (110)-surfaces in iron–silicon sheets was discovered that is attributed to demagnetization effects in direction perpendicular to the sheet surface. - Highlights: • Magnetizing a finite sample in a Kerr microscope leads to sample-generated stray-fields. • They cause non-linear, field- and position-dependent Faraday rotations in the objective. • This leads to a modulation of the Kerr contrast and to distorted MOKE loops. • A method to compensate these Faraday rotations is presented

‘Healthy’ identities? : Revisiting rejection-identification and rejection-disidentification models among voluntary and forced immigrants

NARCIS (Netherlands)

Bobowik, Magdalena; Martinovic, Borja; Basabe, Nekane; Barsties, Lisa S.; Wachter, Gusta

2017-01-01

Rejection-identification and rejection-disidentification models propose that low-status groups identify with their in-group and disidentify with a high-status out-group in response to rejection by the latter. Our research tests these two models simultaneously among multiple groups of foreign-born

Reviewing the pathogenesis of antibody-mediated rejection and renal graft pathology after kidney transplantation.

Science.gov (United States)

Morozumi, Kunio; Takeda, Asami; Otsuka, Yasuhiro; Horike, Keiji; Gotoh, Norihiko; Narumi, Shunji; Watarai, Yoshihiko; Kobayashi, Takaaki

2016-07-01

The clinicopathological context of rejection after kidney transplantation was well recognized. Banff conferences greatly contributed to elucidate the pathogenesis and to establish the pathologic criteria of rejection after kidney transplantation. The most important current problem of renal transplantation is de novo donor-specific antibody (DSA) production leading chronic rejection and graft loss. Microvascular inflammation is considered as a reliable pathological marker for antibody-mediated rejection (AMR) in the presence of DSA. Electron microscopic study allowed us to evaluate early changes in peritubular capillaries in T-lymphocyte mediated rejection and transition to antibody-mediated rejection. Severe endothelial injuries with edema and activated lymphocyte invaded into subendothelial space with early multi-layering of peritubular capillary basement membrane suggest T-lymphocyte mediated rejection induce an unbounded chain of antibody-mediated rejection. The risk factors of AMR after ABO-incompatible kidney transplantation are important issues. Anti-ABO blood type antibody titre of IgG excess 32-fold before transplant operation is the only predictable factor for acute AMR. Characteristics of chronic active antibody-mediated rejection (CAAMR) are one of the most important problems. Light microscopic findings and C4d stain of peritubular capillary and glomerular capillary are useful diagnostic criteria of CAAMR. Microvascular inflammation, double contour of glomerular capillary and thickening of peritubular capillary basement are good predictive factors of the presence of de novo DSA. C4d stain of linear glomerular capillary is a more sensitive marker for CAAMR than positive C4d of peritubular capillary. Early and sensitive diagnostic attempts of diagnosing CAAMR are pivotal to prevent chronic graft failure. © 2016 Asian Pacific Society of Nephrology.

Investigations of prevalence of antibodies to B.canis in stray dogs in territory of Belgrade

Directory of Open Access Journals (Sweden)

Radojičić Sonja

2006-01-01

Full Text Available The paper covers investigations of stray dogs in the territory of the city of Belgrade. A total of 184 blood serum samples were examined for the presence of antibodies specific to Brucella canis. The method of slow agglutination in a test tube with 2- mercaptoethanol was used in the diagnostic procedure. Of the 184 examined serums, 49 (26.63% had a titer of 1/50, 25 serums had a titer of 1/100 (13.58%, while 20 serums had a titer equal to or bigger than 1/200 (10.87%. Furthermore, 15 samples of full blood from serologiclly negative animals were also presented for isolation. The bacteriological finding for these samples was negative. The obtained results indicate that the number of seropositive stray dogs in the territory of Belgrade is extremely high and that 10.87% of the testes animals are definitely infected with Brucella canis.

Helminth Infections of Stray Dogs from Garmsar, Semnan Province, Central Iran

Science.gov (United States)

Eslami, A; Ranjbar-Bahadori, Sh; Meshgi, B; Dehghan, M; Bokaie, S

2010-01-01

Background The aim was to study the gastro-intestinal helminths of stray dogs of Garmsar, Semnan Province, Central Iran, and its impacts on human health and animal production. Methods During 2006, the alimentary tracts of 50 stray dogs at necropsy, selected from villages around Garmsar, were removed, and examined for helminth infections. Subsequently helminths were collected from the contents of each part and scraped sample of small intestines of washed materials in a 100-mesh sieve. To identify the species of helminths, the nematodes were cleared in lactophenol and cestodes were stained using carmine acid. Results Mixed infection was the rule and 40 dogs (80%) harbored more than one species of helminth. Taenia hydatigena was the most prevalent species (80%) followed by Echinococcus granulosus (64%), Toxocara canis (22%), Mesocestoides lineatus (12%), Taenia multiceps (10%) and Dipylidium caninum (4%). The mean intensity of worm infection was low (1–3) except for that of E. granulosus (645). No significant difference was noticed between sex, age and most helminth infections except for that of sex and T. hydatigena (P=0.001) as well as age and T. canis (P=0.001). Conclusion Although human infection with T. hydatigena is unlikely, but other helminths reported in this study are of zoonotic importance, and may pose a threat to community health, and reduce the productions of ruminants harboring taeniid metacestodes. PMID:22347264

A PARASITOLOGIC AND MOLECULAR SURVEY OF HEPATOZOON CANIS INFECTION IN STRAY DOGS IN NORTHEAST OF IRAN.

Science.gov (United States)

Barati, Ali; Razmi, Gholamreza

2018-05-15

Canine hepatozoonosis, caused by H. canis, is a tick-borne disease in domestic and wild dogs that is transmitted by ingestion of Rhipicephalus sanguineus ticks. The aim of the study was to detect H. canis in stray dogs in Iran using blood smear examination and molecular techniques. From October 2014 to September 2015, 150 EDTA blood samples were collected from stray dogs in the northeast region of Iran. Blood smears were microscopically examined for the presence of Hepatozoon gamonts; whole blood was evaluated by PCR, with subsequent sequencing and phylogenetic analysis. Hepatozoon spp. Gamonts were observed in the neutrophils of 5/150 (3.3%) blood smears, whereas Hepatozoon spp. 18S rDNA was detected in 12/150 (8.0%) blood samples from stray dogs. There was a good agreement between microscopy and PCR methods. (Kappa= 0.756). The highest rate of infection was seasonally detected in the summer (pHepatozoon spp infection was not significant by gender and age factors (p>0.05). The alignment analysis of the sequenced samples showed ≥99% similarity with other nucleotide sequences of Hepatozoon spp. in GenBank. The phylogenetic tree also revealed that the nucleotide sequences in this study were clustered in the H. canis clade and different from the H. felis and H. americanum clades. According to the results, it is concluded that H. canis infection is present among dogs in northeastern region of Iran.

Gastrointestinal Helminthic Parasites in Stray Cats (Felis catus from North of Iran

Directory of Open Access Journals (Sweden)

A Rezaei-Doust

2007-08-01

Full Text Available Background: Cats play a crucial role in the epidemiology of gastrointestinal helminthic parasites and also play a major role in transmitting of these parasites through faecal contamination of soil, food or water. The aim of this study was to determine the species of gastrointestinal helminthes parasites in stray cats from a rural area of Bandar-e-Anzali, Iran.Method: Gastrointestinal helminthes were collected from 50 necropsied stray cats (Felis catus after capturing them by trapping from different regions of the city and humanely euthanatized in Bandar-e-Anzali, a port in the Caspian Sea in northern Iran, from March to November 2003. Results: The prevalence of infection was 90%, with those of individual parasites being Diplopylidium nolleri 54%, Phy­saloptera praeputialis 32%, Ancylostoma tubaeforme 20%, Joyeuxiella pasqualei 10%, Toxocara cati 8%, Pterygoderma­tites affinis 6%, Ancylostoma caninum 4%, and Taenia taeniaeformis 2%. Concurrent infections with two or more parasites were recorded in 34% of the individuals. In relation to the sex, the differences were not significant. Conclusion: P. praeputialis, T. cati, D. nolleri and sometime J. pasqualei are the commonest Helminthes in cats. This is the first reported isolation of P. affinis and A. caninum infections from cats in Iran.

Radionuclide diagnosis of allograft rejection

International Nuclear Information System (INIS)

George, E.A.

1982-01-01

Interaction with one or more anatomical and physiopathological characteristics of the rejecting renal allograft is suggested by those radioagents utilized specifically for the diagnosis of allograft rejection. Rejection, the most common cause of declining allograft function, is frequently mimicked clinically or masked by other immediate or long term post transplant complications. Understanding of the anatomical pathological features and kinetics of rejection and their modification by immunosuppressive maintenance and therapy are important for the proper clinical utilization of these radioagents. Furthermore, in selecting these radionuclides, one has to consider the comparative availability, preparatory and procedural simplicity, acquisition and display techniques and the possibility of timely report. The clinical utilities of radiofibrinogen, /sup 99m/Tc sulfur colloid and 67 Ga in the diagnosis of allograft rejection have been evaluated to a variable extent in the past. The potential usefulness of the recently developed preparations of 111 In labeled autologous leukocytes and platelets are presently under investigation

Comment on "Density functional theory is straying from the path toward the exact functional"

DEFF Research Database (Denmark)

Kepp, Kasper Planeta

2017-01-01

Medvedev et al (Reports, 6 January 2017, p. 49) argue that recent density functionals stray from the path toward exactness. This conclusion rests on very compact 1s2 and 1s22s2 systems favored by the Hartree-Fock picture. Comparison to actual energies for the same systems indicates that the "stra...

Preemptive scheduling with rejection

NARCIS (Netherlands)

Hoogeveen, H.; Skutella, M.; Woeginger, Gerhard

2003-01-01

We consider the problem of preemptively scheduling a set of n jobs on m (identical, uniformly related, or unrelated) parallel machines. The scheduler may reject a subset of the jobs and thereby incur job-dependent penalties for each rejected job, and he must construct a schedule for the remaining

Preemptive scheduling with rejection

NARCIS (Netherlands)

Hoogeveen, J.A.; Skutella, M.; Woeginger, G.J.; Paterson, M.

2000-01-01

We consider the problem of preemptively scheduling a set of n jobs on m (identical, uniformly related, or unrelated) parallel machines. The scheduler may reject a subset of the jobs and thereby incur job-dependent penalties for each rejected job, and he must construct a schedule for the remaining

LATE RENAL GRAFT REJECTION: PATHOLOGY AND PROGNOSIS

Directory of Open Access Journals (Sweden)

E.S. Stolyarevich

2014-01-01

Full Text Available Rejection has always been one of the most important cause of late renal graft dysfunction. Aim of the study was to analyze the prevalence of different clinico-pathological variants of rejection that cause late graft dysfunction, and evaluate their impact on long-term outcome. Materials and methods. This is a retrospective study that analyzed 294 needle core biopsy specimens from 265 renal transplant recipients with late (48,8 ± 46,1 months after transplantation allograft dysfunction caused by late acute rejection (LAR, n = 193 or chronic rejection (CR, n = 78 or both (n = 23. C4d staining was performed by immunofl uorescence (IF on frozen sections using a standard protocol. Results. Peritubular capillary C4d deposition was identifi ed in 36% samples with acute rejection and in 62% cases of chronic rejection (including 67% cases of transplant glomerulopathy, and 50% – of isolated chronic vasculopathy. 5-year graft survival for LAR vs CR vs their combination was 47, 13 and 25%, respectively. The outcome of C4d– LAR was (p < 0,01 better than of C4d+ acute rejection: at 60 months graft survival for diffuse C4d+ vs C4d− was 33% vs 53%, respectively. In cases of chronic rejection C4d+ vs C4d– it was not statistically signifi cant (34% vs 36%. Conclusion. In long-term allograft biopsy C4d positivity is more haracteristic for chronic rejection than for acute rejection. Only diffuse C4d staining affects the outcome. C4d– positivity is associated with worse allograft survival in cases of late acute rejection, but not in cases of chronic rejection. 

Barged/In-river steelhead migrant data - Evaluation of methods to reduce straying rates of barged juvenile steelhead

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The goals of this study are to develop methods to reduce wandering and straying of steelhead (Oncorhynchus mykiss) that are collected and barged from the Snake River...

Laboratory data on Snake River steelhead - Evaluation of methods to reduce straying rates of barged juvenile steelhead

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The goals of this study are to develop methods to reduce wandering and straying of steelhead (Oncorhynchus mykiss) that are collected and barged from the Snake River...

A survey study on gastrointestinal parasites of stray cats in northern region of Nile delta, Egypt.

Directory of Open Access Journals (Sweden)

Reda E Khalafalla

Full Text Available A survey study on gastrointestinal parasites in 113 faecal samples from stray cats collected randomly from Kafrelsheikh province, northern region of Nile delta of Egypt; was conducted in the period between January and May 2010. The overall prevalence was 91%. The results of this study reported seven helminth species: Toxocara cati (9%, Ancylostoma tubaeforme (4%, Toxascaris leonina (5%, Dipylidium caninum (5%, Capillaria spp. (3%, Taenia taeniformis (22% and Heterophyes heterophyes (3%, four protozoal species: Toxoplasma gondii (9%, Sarcocyst spp. (1%, Isospora spp. (2% and Giardia spp. (2% and two arthropod species; Linguatula serrata (2% and mites eggs (13%. The overall prevalence of intestinal parasites may continue to rise due to lack of functional veterinary clinics for cat care in Egypt. Therefore, there is a need to plan adequate control programs to diagnose, treat and control gastrointestinal parasites of companion as well as stray cats in the region.

A Survey Study on Gastrointestinal Parasites of Stray Cats in Northern Region of Nile Delta, Egypt

Science.gov (United States)

Khalafalla, Reda E.

2011-01-01

A survey study on gastrointestinal parasites in 113 faecal samples from stray cats collected randomly from Kafrelsheikh province, northern region of Nile delta of Egypt; was conducted in the period between January and May 2010. The overall prevalence was 91%. The results of this study reported seven helminth species: Toxocara cati (9%), Ancylostoma tubaeforme (4%), Toxascaris leonina (5%), Dipylidium caninum (5%), Capillaria spp. (3%), Taenia taeniformis (22%) and Heterophyes heterophyes (3%), four protozoal species: Toxoplasma gondii (9%), Sarcocyst spp. (1%), Isospora spp. (2%) and Giardia spp. (2%) and two arthropod species; Linguatula serrata (2%) and mites eggs (13%). The overall prevalence of intestinal parasites may continue to rise due to lack of functional veterinary clinics for cat care in Egypt. Therefore, there is a need to plan adequate control programs to diagnose, treat and control gastrointestinal parasites of companion as well as stray cats in the region. PMID:21760884

Helminth Infections of Stray Dogs from Garmsar, Semnan Province, Central Iran

Directory of Open Access Journals (Sweden)

A Eslami

2010-12-01

Full Text Available Background: The aim was to study the gastro-intestinal helminths of stray dogs of Garmsar, Sem­nan Province, Central Iran, and its impacts on human health and animal production.Methods: During 2006, the alimentary tracts of 50 stray dogs at necropsy, selected from villages around Garmsar, were removed, and examined for helminth infections. Subsequently helminths were collected from the contents of each part and scraped sample of small intestines of washed materials in a 100-mesh sieve. To identify the species of helminths, the nematodes were cleared in lactophenol and cestodes were stained using carmine acid.Results: Mixed infection was the rule and 40 dogs (80% harbored more than one species of helminth. Taenia hydatigena was the most prevalent species (80% followed by Echinococcus granulosus (64%, Toxocara canis (22%, Mesocestoides lineatus (12%, Taenia multiceps (10% and Dipylidium caninum (4%. The mean intensity of worm infection was low (1-3 ex­cept for that of E. granulosus (645. No significant difference was noticed between sex, age and most helminth infections except for that of sex and T. hydatigena (P=0.001 as well as age and T. canis (P=0.001.Conclusion: Although human infection with T. hydatigena is unlikely, but other helminths re­ported in this study are of zoonotic importance, and may pose a threat to community health, and reduce the productions of ruminants harboring taeniid metacestodes.

Midcourse Space Experiment: Off-Axis Rejection Performance of the Infrared Sensor

National Research Council Canada - National Science Library

O'Neil, R. R; Gibson, J; Richards, E

2005-01-01

.... Analysis indicates that direct scatter of terrestrial radiance from contaminants on the telescope primary mirror is the principal source of stray radiation and the bidirectional reflectance distribution function (BRDF...

7 CFR 58.136 - Rejected milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Rejected milk. 58.136 Section 58.136 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Milk § 58.136 Rejected milk. A plant shall reject specific milk from a producer if the milk fails to...

A Preliminary Study on the Helminth Fauna in Necropsied Stray Cats (Felis catus in Beni-Suef, Egypt

Directory of Open Access Journals (Sweden)

Khaled Mohamed El-Dakhly

2017-10-01

Full Text Available Stray cats play a crucial role in the epidemiology of endoparasites, particularly helminths, due to predating a wide range of both vertebrate and invertebrate hosts, often of veterinary and zoonotic importance. Therefore, a total of 62 stray cats were necropsied in Beni-Suef province, Egypt and examined for helminth parasites. The overall prevalence of infection was 87.0%. The recovered helminths consisted of 10 species of trematodes (Heterophyes heterophyes, Pygidiopsis summa, H. nocens, Echinochasmus liliputanus, Alaria sp., Procerovum varium, Ascocotyle sp., Haplorchis sp., Prohemistomum vivax, Euparadistomum herpestesi, five cestodes (Dipylidium caninum, Diplopylidium acanthoterta, D. nolleri, Joyeuxiella sp. and Taenia taeniaeformis, and two nematodes (Toxascaris leonina and larvae of Anisakis simplex. The most prevalent helminths were Dipylidium caninum (62.9%, Toxascaris leonina (33.8%, Diplopylidium nolleri (22.5% and Echinochasmus liliputanus (6.45%. Thirty (48.39% cats were co-infected by one species, 22 (35.48% by two and three (4.84% by more than two species. It has been found that cats aged more than 3 years were the most infected. Both male and female cats were parasitized. The infection was the most prevalent in both summer and autumn. In conclusion, veterinarians must highlight more attention towards both stray and domestic cats, as they are considered reservoir hosts for a wide host range of parasites, particularly helminths, and the zoonotic importance of such parasites should be taken on consideration.

MR imaging of renal transplant rejection

International Nuclear Information System (INIS)

Hanna, S.; Helenon, O.; Legendre, C.; Chichie, J.F.; Di Stefano, D.; Kreis, H.; Moreau, J.F.; Hopital Necker, 75 - Paris

1991-01-01

The results of 62 consecutive MR examinations were correlated with the subsequent clinical course and histologic results. Twenty-six cases of rejection showed a marked diminution of cortico-medullary differentiation (CMD). The renal parenchymal vascular pattern and visibility of renal sinus fat were not markedly altered in rejection and there was no difference between normal and rejected allograft shape. The ability of MR imaging to diagnose renal transplant rejection is only based on CMD, which, however, is non-specific. In 2 cases of severe rejection, T2 weighted images showed an abnormal signal intensity of the cortex due to renal infarction. Our preliminary results in 8 patients with Gd-DOTA injection showed 2 cases with necrosis seen as areas with absent contrast enhancement. This technique seems to be promising in the detection of perfusion defects. (orig.)

Some aspects of stray losses in large power transformers

International Nuclear Information System (INIS)

Valkovic, Zvonimir

2002-01-01

The paper presents some results of the investigation of stray losses in power transformers that are caused by high-current loops. The investigation was focused on: a) additional losses in tank cover around high-current bushings and the way of their reduction, b) extra leakage flux and additional losses due to high current delta-connections. The insertion of nonmagnetic gaps between the phase bushings reduces the extra cover losses more than three times. A nonmagnetic plate around the high-current bushings reduces these extra losses practically to zero. The extra losses due to the high-current delta-connections could be significant for the transformer loss level. These extra losses could be controlled (reduced) by the design layout of the delta-connections. (Author)

Possibility of reducing stray losses and parasitic torques in two-phase emergency feeding of induction motors

Czech Academy of Sciences Publication Activity Database

Schreier, Luděk; Bendl, Jiří; Chomát, Miroslav; Klíma, J.

2006-01-01

Roč. 51, č. 2 (2006), s. 109-131 ISSN 0001-7043 R&D Projects: GA ČR(CZ) GA102/04/0215 Institutional research plan: CEZ:AV0Z20570509 Keywords : induction motor * emergency operation of electrical drives * stray losses Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

Magnetic charge distribution and stray field landscape of asymmetric néel walls in a magnetically patterned exchange bias layer system

Science.gov (United States)

Zingsem, Norbert; Ahrend, Florian; Vock, Silvia; Gottlob, Daniel; Krug, Ingo; Doganay, Hatice; Holzinger, Dennis; Neu, Volker; Ehresmann, Arno

2017-12-01

The 3D stray field landscape above an exchange bias layer system with engineered domain walls has been fully characterized by quantitative magnetic force microscopy (qMFM) measurements. This method is based on a complete quantification of the MFM tip’s imaging properties and the subtraction of its contribution from the measured MFM data by deconvolution in Fourier space. The magnetically patterned Ir17Mn83/Co70Fe30-exchange-bias-multilayers have been designed to contain asymmetric head-to-head (hh)/tail-to-tail (tt) Néel walls between domains of different magnetic anisotropies for potential use in guided particle transport. In the current application, qMFM reveals the effective magnetic charge profile on the surface of the sample—with high spatial resolution and in an absolute quantitative manner. These data enable to calculate the magnetostatic potential and the full stray field landscape above the sample surface. It has been successfully tested against: (i) micromagnetic simulations of the magnetization structure of a comparable exchange-bias layer system, (ii) measurements of the magnetization profile across the domain boundary with x-ray photoemission electron microscopy, and (iii) direct stray field measurements obtained by scanning Hall probe microscopy at elevated scan heights. This approach results in a quantitative determination of the stray field landscape at close distances to the sample surface, which will be of importance for remote magnetic particle transport applications in lab-on-a-chip devices. Furthermore, the highly resolving and quantitative MFM approach reveals details of the domain transition across the artificially structured phase boundary, which have to be attributed to a continuous change in the materials parameters across this boundary, rather than an abrupt one.

The significance of parenchymal changes of acute cellular rejection in predicting chronic liver graft rejection

NARCIS (Netherlands)

Gouw, ASH; van den Heuvel, MC; van den Berg, AP; Slooff, NJH; de Jong, KP; Poppema, S

2002-01-01

Background. Chronic rejection (CR) in liver allografts shows a rapid onset and progressive course, leading to graft failure within the first year after transplantation. Most cases are preceded by episodes of acute cellular rejection (AR), but histological features predictive for the transition

Preventing Rejection

Science.gov (United States)

... After the transplant Preventing rejection Post-transplant medications Types of immunosuppressants Switching immunosuppressants Side effects Other medications Generic and brand name drugs Post-transplant tests Infections and immunity Lifestyle changes Health concerns Back to work or ...

3D Printing of Polymer-Bonded Rare-Earth Magnets With a Variable Magnetic Compound Fraction for a Predefined Stray Field.

Science.gov (United States)

Huber, Christian; Abert, Claas; Bruckner, Florian; Groenefeld, Martin; Schuschnigg, Stephan; Teliban, Iulian; Vogler, Christoph; Wautischer, Gregor; Windl, Roman; Suess, Dieter

2017-08-25

Additive manufacturing of polymer-bonded magnets is a recently developed technique, for single-unit production, and for structures that have been impossible to manufacture previously. Also, new possibilities to create a specific stray field around the magnet are triggered. The current work presents a method to 3D print polymer-bonded magnets with a variable magnetic compound fraction distribution. This means the saturation magnetization can be adjusted during the printing process to obtain a required external field of the manufactured magnets. A low-cost, end-user 3D printer with a mixing extruder is used to mix permanent magnetic filaments with pure polyamide (PA12) filaments. The magnetic filaments are compounded, extruded, and characterized for the printing process. To deduce the quality of the manufactured magnets with a variable magnetic compound fraction, an inverse stray field framework is developed. The effectiveness of the printing process and the simulation method is shown. It can also be used to manufacture magnets that produce a predefined stray field in a given region. This opens new possibilities for magnetic sensor applications. This setup and simulation framework allows the design and manufacturing of polymer-bonded permanent magnets, which are impossible to create with conventional methods.

Heterosexual Rejection and Mate Choice: A Sociometer Perspective

Directory of Open Access Journals (Sweden)

Lin eZHANG

2015-12-01

Full Text Available Previous studies about the effects of social rejection on individuals’ social behaviors have produced mixed results and tend to study mating behaviors from a static point of view. However, mate selection in essence is a dynamic process, and therefore sociometer theory opens up a new perspective for studying mating and its underlying practices. Based on this theory and using self-perceived mate value in the relationship between heterosexual rejection and mate choice as a mediating role, this current study examined the effects of heterosexual rejection on mate choice in two experiments. Results showed that heterosexual rejection significantly reduced self-perceived mate value, expectation, and behavioral tendencies, while heterosexual acceptance indistinctively increased these measures. Self-perceived mate value did not serve as a mediator in the relationship between heterosexual rejection and mate expectation, but it mediated the relationship between heterosexual rejection and mating behavior tendencies towards potential objects. Moreover, individuals evaded both rejection and irrelevant people when suffering from rejection.

Toxocara nematodes in stray cats from shiraz, southern iran: intensity of infection and molecular identification of the isolates.

Directory of Open Access Journals (Sweden)

Fattaneh Mikaeili

2013-12-01

Full Text Available Toxocara is a common nematode of cats in different parts of Iran. Despite the close association of cats with human, no attempt has been done so far for molecular identification of this nematode in the country. Therefore, current study was performed on identification of some isolates of Toxocara from stray cats in Shiraz, Fars Province, Southern Iran, based on morphological and molecular approaches, and also determination of intensity of infection.This cross-sectional study was carried out on 30 stray cats trapped from different geographical areas of Shiraz in 2011. Adult male and female worms were recovered from digestive tract after dissection of cats. Morphological features using existing keys and PCR-sequencing of ITS-rDNA region and pcox1 mitochondrial l gene were applied for the delineating the species of the parasites.Eight out of 30 cats (26.7% were found infected with Toxocara nematodes. All the isolates were confirmed as Toxocara cati based on morphological features and the sequence of ribosomal and mitochondrial targets. Intensity of infection ranged from one to a maximum of 39 worms per cat, with a mean of 10.25±12.36, and higher abundance of female nematodes.The most prevalent ascaridoid nematode of stray cats in the study area was T. cati and female nematodes were more abundant than that of males. This issue has important role in spreading of eggs in the environment and impact on human toxocariasis.

Thomson scattering on a low-pressure, inductively-coupled gas discharge lamp

International Nuclear Information System (INIS)

Sande, M.J. van de; Mullen, J.J.A.M. van der

2002-01-01

Excitation and light production processes in gas discharge lamps are the result of inelastic collisions between atoms and free electrons in the plasma. Therefore, knowledge of the electron density n e and temperature T e is essential for a proper understanding of such plasmas. In this paper, an experimental system for laser Thomson scattering on a low-pressure, inductively-coupled gas discharge lamp and measurements of n e and T e in this lamp are presented. The experimental system is suitable for low electron temperatures (down to below 0.2 eV) and employs a triple grating spectrograph for a high stray light rejection, or equivalently a low stray light redistribution (R eff approximately 7x10 -9 nm -1 at 0.5 nm from the laser wavelength). The electron density detection limit of the system is n e approximately 10 16 m -3 . The modifications to the lamp that were necessary for the measurements are described, and results are presented and compared to previous work and trends expected from the electron particle and energy balances. The electron density and temperature are about n e approximately 10 19 m -3 and T e approximately 1 eV in the most active part of the plasma; the exact values depend on the argon filling pressure, the mercury pressure and the position in the lamp. (author)

Measurement of stray neutron doses inside the treatment room from a proton pencil beam scanning system

Czech Academy of Sciences Publication Activity Database

Mojzeszek, N.; Farah, J.; Klodowska, M.; Ploc, Ondřej; Stolarczyk, L.; Waligorski, M. P. R.; Olko, P.

2017-01-01

Roč. 34, č. 2 (2017), s. 80-84 ISSN 1120-1797 Institutional support: RVO:61389005 Keywords : secondary neutrons * proton therapy * pencil beam scanning systtems * out-of-field doses * stray neutron doses * TEPC Subject RIV: FP - Other Medical Disciplines OBOR OECD: Radiology, nuclear medicine and medical imaging Impact factor: 1.990, year: 2016

Humoral immune response to Dipylidium caninum infection of stray dogs in Taiwan.

Science.gov (United States)

Shin, J W; Liao, W T

2002-04-02

Two kinds of homogeneous proglottid, mature and gravid, of Dipylidium caninum were used as the antigens for immunodiagnosis of canine dipylidiosis in stray dogs in Tainan, Taiwan. The ELISA was performed on 30 serum samples; 24 from dipylidiosis, four from ancylostomosis and two from toxocariosis. The ELISA have specificity and sensitive of 100 and 50% for mature proglottid extract, and 75 and 100%, respectively, for gravid proglottid extract. EITB technique showed two major peptide bands of 94.8 and 97.9kDa were recognized in the sera pool of infected dogs.

Induced radioactivity of materials by stray radiation fields at an electron accelerator

CERN Document Server

Rokni, S H; Gwise, T; Liu, J C; Roesler, S

2002-01-01

Samples of soil, water, aluminum, copper and iron were irradiated in the stray radiation field generated by the interaction of a 28.5 GeV electron beam in a copper-dump in the Beam Dump East facility at the Stanford Linear Accelerator Center. The specific activity induced in the samples was measured by gamma spectroscopy and other techniques. In addition, the isotope production in the samples was calculated with detailed Monte Carlo simulations using the FLUKA code. The calculated activities are compared to the experimental values and differences are discussed.

Social Causes and Consequences of Rejection Sensitivity

Science.gov (United States)

London, Bonita; Downey, Geraldine; Bonica, Cheryl; Paltin, Iris

2007-01-01

Predictions from the Rejection Sensitivity (RS) model concerning the social causes and consequences of RS were examined in a longitudinal study of 150 middle school students. Peer nominations of rejection, self-report measures of anxious and angry rejection expectations, and social anxiety, social withdrawal, and loneliness were assessed at two…

Toward Microsatellite Based Space Situational Awareness

Science.gov (United States)

Scott, L.; Wallace, B.; Sale, M.; Thorsteinson, S.

2013-09-01

The NEOSSat microsatellite is a dual mission space telescope which will perform asteroid detection and Space Situational Awareness (SSA) observation experiments on deep space, earth orbiting objects. NEOSSat was launched on 25 February 2013 into a 800 dawn-dusk sun synchronous orbit and is currently undergoing satellite commissioning. The microsatellite consists of a small aperture optical telescope, GPS receiver, high performance attitude control system, and stray light rejection baffle designed to reject stray light from the Sun while searching for asteroids with elongations 45 degrees along the ecliptic. The SSA experimental mission, referred to as HEOSS (High Earth Orbit Space Surveillance), will focus on objects in deep space orbits. The HEOSS mission objective is to evaluate the utility of microsatellites to perform catalog maintenance observations of resident space objects in a manner consistent with the needs of the Canadian Forces. The advantages of placing a space surveillance sensor in low Earth orbit are that the observer can conduct observations without the day-night interruption cycle experienced by ground based telescopes, the telescope is insensitive to adverse weather and the system has visibility to deep space resident space objects which are not normally visible from ground based sensors. Also, from a photometric standpoint, the microsatellite is able to conduct observations on objects with a rapidly changing observer position. The possibility of spin axis estimation on geostationary satellites may be possible and an experiment characterize spin axis of distant resident space objects is being planned. Also, HEOSS offers the ability to conduct observations of satellites at high phase angles which can potentially extend the trackable portion of space in which deep space objects' orbits can be monitored. In this paper we describe the HEOSS SSA experimental data processing system and the preliminary findings of the catalog maintenance experiments

Factors affecting the prevalence of mange-mite infestations in stray dogs of Yucatán, Mexico.

Science.gov (United States)

Rodriguez-Vivas, R I; Ortega-Pacheco, A; Rosado-Aguilar, J A; Bolio, G M E

2003-07-10

The aim of the present study was to determine the factors affecting the prevalence of mange-mite infestations in stray dogs of Yucatán, Mexico. The study was carried out in 200 stray dogs of Mérida capital city of Yucatán, Mexico. Four samples (head, thoracic-abdominal area, extremities and ear) were taken from each animal by skin scraping and examined microscopically in 10% KOH solution to detect the presence of mites. Mites were also collected from the external ear canal of dogs using cotton-tipped swabs. The prevalence of different mite species was calculated. A primary screening was performed using 2xK contingency tables of exposure variables. All variables with PDemodex canis (23.0%) was the most frequent mite, followed by Sarcoptes scabei var. canis (7.0%) and Otodectes cynotis (3.5%). The following factors were found: body condition (bad, OR: 5.35, CI 95%: 1.66-17.3; regular, OR: 3.72, CI 95%: 1.39-9.99) and the presence of macroscopic lesions of dermatosis (OR: 42.80, CI 95%: 13.65-134.24).

Peer Group Rejection and Children's Outgroup Prejudice

Science.gov (United States)

Nesdale, Drew; Durkin, Kevin; Maass, Anne; Kiesner, Jeff; Griffiths, Judith; Daly, Josh; McKenzie, David

2010-01-01

Two simulation studies examined the effect of peer group rejection on 7 and 9 year old children's outgroup prejudice. In Study 1, children (n = 88) pretended that they were accepted or rejected by their assigned group, prior to competing with a lower status outgroup. Results indicated that rejected versus accepted children showed increased…

Antibody Detection to Feline Immunodeficiency virus (FIV in stray cats in Ahvaz, southwestern Iran

Directory of Open Access Journals (Sweden)

Mosallanejad, B.

2010-01-01

Full Text Available The present study was performed to determine the prevalence of FIV in stray cat's population of Ahvaz different area. Serum samples were collected from 90 cats from 2005 to 2007. The studied cats were divided into two age groups (3 years and based on clinical signs (such as lymphadenopathy, periodontal diseases, gingivitis, abscess and cashecsi into two groups also. The results were analyzed using Fischer's exact test and Chi-square analysis. Prevalence to FIV antibodies in these cats was 15.55% (14 of 90 by means of ELISA Test Kit, indicating that this virus is present in the ecosystem. The infection had more prevalence in cats above 3 years (78.6%; 11 of 14 compared with cats less than 3 years (21.4%; 3 of 14. Statistical analysis showed significant difference between different age groups (P0.05. Three out of 12 cases (25% which had clinical signs and 11 out of 78 cases (14.1% which hadn’t clinical signs were seropositive. There was no significant difference between the two groups also (P>0.05. This study showed that FIV exist among cat's population of Ahvaz area and separation of companion and stray cats is very important for prevention of disease transmission to companion cats.

Community perception regarding rabies prevention and stray dog control in urban slums in India.

Science.gov (United States)

Herbert, Mrudu; Riyaz Basha, S; Thangaraj, Selvi

2012-12-01

The lack of community awareness about rabies control is a major issue that thwarts efforts to prevent human deaths caused by rabies. The objectives of this study were (1) to assess community knowledge and attitudes about rabies, rabies prevention and stray dog control in an urban slum community and (2) to determine the factors that influence rabies awareness in urban slums. Using a systematic random sampling strategy, 185 participants were selected from 8 urban slums. The data were collected by direct interview using a pre-tested, structured questionnaire. In the study population, 74.1% of the participants had heard about rabies, and 54.1% knew that rabies is a fatal disease. Only 33.5% of the interviewees felt that people in the community had a role to play in controlling the stray dog population. Gender, age and educational status were significantly associated with rabies awareness. Our study indicates that there are gaps in the knowledge and attitudes of individuals living in urban slums regarding rabies prevention and control. Efforts to promote awareness should be targeted at men, older people and uneducated individuals. Copyright © 2012 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.

Upgrade of the Automatic Analysis System in the TJ-II Thomson Scattering Diagnostic: New Image Recognition Classifier and Fault Condition Detection

Energy Technology Data Exchange (ETDEWEB)

Makili, L.; Dormido-Canto, S. [UNED, Madrid (Spain); Vega, J.; Pastor, I.; Pereira, A.; Portas, A.; Perez-Risco, D.; Rodriguez-Fernandez, M. [Association EuratomCIEMAT para Fusion, Madrid (Spain); Busch, P. [FOM Instituut voor PlasmaFysica Rijnhuizen, Nieuwegein (Netherlands)

2009-07-01

Full text of publication follows: An automatic image classification system has been in operation for years in the TJ-II Thomson diagnostic. It recognizes five different types of images: CCD camera background, measurement of stray light without plasma or in a collapsed discharge, image during ECH phase, image during NBI phase and image after reaching the cut o density during ECH heating. Each kind of image implies the execution of different application software. Therefore, the classification system was developed to launch the corresponding software in an automatic way. The method to recognize the several classes was based on a learning system, in particular Support Vector Machines (SVM). Since the first implementation of the classifier, a relevant improvement has been accomplished in the diagnostic: a new notch filter is in operation, having a larger stray-light rejection at the ruby wavelength than the previous filter. On the other hand, its location in the optical system has been modified. As a consequence, the stray light pattern in the CCD image is located in a different position. In addition to these transformations, the power of neutral beams injected in the TJ-II plasma has been increased about a factor of 2. Due to the fact that the recognition system is based on a learning system and major modifications have been carried out in both the diagnostic (optics) and TJ-II plasmas (injected power), the classifier model is no longer valid. The creation of a new model (also based on SVM) under the present conditions has been necessary. Finally, specific error conditions in the data acquisition process can automatically be detected now. The recovering process can be automated, thereby avoiding the loss of data in ensuing discharges. (authors)

Risk of renal allograft rejection following angiography

International Nuclear Information System (INIS)

Heideman, M.; Claes, G.; Nilson, A.E.

1976-01-01

In a retrospective study of 173 immediately functioning primary kidney transplants, correlation between angiography and renal allograft rejection was studied during the first 14 days. It was found that rejection was more frequent in kidneys undergoing angiography than in those not undergoing angiography. It was also found that in kidneys undergoing angiography an overwhelming number of the rejections started the day after angiography. These differences in rejection frequency could not be explained by differences in HLA matching or the origin of the kidneys. These findings suggest a possible connection indicating that the angiography might elicit an acute rejection episode. A possible mechanism for starting this reaction might be activation of the complement system which was found in 50 percent of the patients undergoing angiography in peripheral blood and in 100 percent when studied in vitro

Determining coronal electron temperatures from observations with UVCS/SOHO

Science.gov (United States)

Fineschi, S.; Esser, R.; Habbal, S. R.; Karovska, M.; Romoli, M.; Strachan, L.; Kohl, J. L.; Huber, M. C. E.

1995-01-01

The electron temperature is a fundamental physical parameter of the coronal plasma. Currently, there are no direct measurements of this quantity in the extended corona. Observations with the Ultraviolet Coronagraph Spectrometer (UVCS) aboard the upcoming Solar and Heliospheric Observatory (SOHO) mission can provide the most direct determination of the electron kinetic temperature (or, more precisely, the electron velocity distribution along the line of sight). This measurement is based on the observation of the Thomson-scattered Lyman alpha (Ly-alpha) profile. This observation is made particularly challenging by the fact that the integrated intensity of the electron-scattered Ly-alpha line is about 10(exp 3) times fainter than that of the resonantly-scattered Ly-alpha component. In addition, the former is distributed across 50 A (FWHM), unlike the latter that is concentrated in 1 A. These facts impose stringent requirements on the stray-light rejection properties of the coronagraph/spectrometer, and in particular on the requirements for the grating. We make use of laboratory measurements of the UVCS Ly-alpha grating stray-light, and of simulated electron-scattered Ly-alpha profiles to estimate the expected confidence levels of electron temperature determination. Models of different structures typical of the corona (e.g., streamers, coronal holes) are used for this parameter study.

Phase1 upgrade of the CMS-HF Calorimeter

CERN Document Server

Gulmez, Erhan

2016-01-01

In this presentation, results of the Phase I upgrade of the CMS Hadron Forward Calorimeter (HF) are discussed. The CMS-HF Calorimeter was using regular PMTs. Cherenkov light produced in the quartz fibers embedded in the iron absorber was read out with the PMTs. However, occasionally, stray muons hitting the PMT windows cause Cherenkov radiation in the PMT itself and produce large signals. These large signals mimic a very high-energy particle and are tagged as important by the trigger. To reduce this problem, PMTs had to be replaced. The four-anode PMTs that were chosen have thinner windows; thereby reducing the Cherenkov radiation in the PMT window. As part of the upgrade, the read-out electronics is to be replaced so that the PMTs are read out in two channels by connecting each pair of anodes to a single channel. Information provided by these two channels will help us reject the false signals due to the stray muons since the Cherenkov radiation in the PMT window is more likely to produce a signal only in one...

111-Indium-labelled platelets for diagnosis of acute kidney transplant rejection and monitoring of prostacyclin anti-rejection treatment

International Nuclear Information System (INIS)

Leithner, C.; Pohanka, E.; Schwarz, M.; Sinzinger, H.; Syre, G.

1984-01-01

33 patients were examined daily under a gamma camera after weekly injections of 111-In-labelled autologous platelets over a period of at least 4 weeks after transplantation. A group of 33 patients with long-term stable and well-functioning grafts served as controls. By means of a computerized recording technique, platelet trapping in the graft was measured and expressed as platelet-uptake index (PUI). The method worked well for the early diagnosis of acute rejection signified by an increase in PUI, accompanied by a shortening of platelet half life (t/2). 6 patients suffering from acute rejection received infusions of prostacyclin in addition to conventional high-dose methylprednisolone therapy. In 4 cases the PUI decreased again and an improvement in graft function was observed. Prostacyclin infusion treatment was applied also in 12 patients with histologically-proven chronic transplant rejection. Decreased platelet consumption by the graft and a temporary improvement in transplant function were achieved. We suggest that prostacyclin could enrich the possibilities of anti-rejection treatment by providing a tool for the suppression of platelet trapping in the graft. The platelet scan served as a useful method for the early detection of acute rejection, as well as the monitoring of prostacyclin anti-rejection treatment. (Autor)

Rejection Sensitivity, Jealousy, and the Relationship to Interpersonal Aggression.

Science.gov (United States)

Murphy, Anna M; Russell, Gemma

2018-07-01

The development and maintenance of interpersonal relationships lead individuals to risk rejection in the pursuit of acceptance. Some individuals are predisposed to experience a hypersensitivity to rejection that is hypothesized to be related to jealous and aggressive reactions within interpersonal relationships. The current study used convenience sampling to recruit 247 young adults to evaluate the relationship between rejection sensitivity, jealousy, and aggression. A mediation model was used to test three hypotheses: Higher scores of rejection sensitivity would be positively correlated to higher scores of aggression (Hypothesis 1); higher scores of rejection sensitivity would be positively correlated to higher scores of jealousy (Hypothesis 2); jealousy would mediate the relationship between rejection sensitivity and aggression (Hypothesis 3). Study results suggest a tendency for individuals with high rejection sensitivity to experience higher levels of jealousy, and subsequently have a greater propensity for aggression, than individuals with low rejection sensitivity. Future research that substantiates a link between hypersensitivity to rejection, jealousy, and aggression may provide an avenue for prevention, education, or intervention in reducing aggression within interpersonal relationships.

Corneal Graft Rejection: Incidence and Risk Factors

Directory of Open Access Journals (Sweden)

Alireza Baradaran-Rafii

2008-12-01

Full Text Available

PURPOSE: To determine the incidence and risk factors of late corneal graft rejection after penetrating keratoplasty (PKP. METHODS: Records of all patients who had undergone PKP from 2002 to 2004 without immunosuppressive therapy other than systemic steroids and with at least one year of follow up were reviewed. The role of possible risk factors such as demographic factors, other host factors, donor factors, indications for PKP as well as type of rejection were evaluated. RESULTS: During the study period, 295 PKPs were performed on 286 patients (176 male, 110 female. Mean age at the time of keratoplasty was 38±20 (range, 40 days to 90 years and mean follow up period was 20±10 (range 12-43 months. Graft rejection occurred in 94 eyes (31.8% at an average of 7.3±6 months (range, 20 days to 39 months after PKP. The most common type of rejection was endothelial (20.7%. Corneal vascularization, regrafting, anterior synechiae, irritating sutures, active inflammation, additional anterior segment procedures, history of trauma, uncontrolled glaucoma, prior graft rejection, recurrence of herpetic infection and eccentric grafting increased the rate of rejection. Patient age, donor size and bilateral transplantation had no significant influence on graft rejection. CONCLUSION: Significant risk factors for corneal graft rejection include

Thallium kinetics in rat cardiac transplant rejection

International Nuclear Information System (INIS)

Barak, J.H.; LaRaia, P.J.; Boucher, C.A.; Fallon, J.T.; Buckley, M.J.

1988-01-01

Cardiac transplant rejection is a very complex process involving both cellular and vascular injury. Recently, thallium imaging has been used to assess acute transplant rejection. It has been suggested that changes in thallium kinetics might be a sensitive indicator of transplant rejection. Accordingly, thallium kinetics were assessed in vivo in acute untreated rat heterotopic (cervical) transplant rejection. Male Lewis rats weighing 225-250 g received heterotopic heart transplants from syngeneic Lewis rats (group A; n = 13), or allogeneic Brown Norway rats (group B; n = 11). Rats were imaged serially on the 2nd and the 7th postoperative days. Serial cardiac thallium content was determined utilizing data collected every 150 sec for 2 hr. The data were fit to a monoexponential curve and the decay rate constant (/sec) derived. By day 7 all group B hearts had histological evidence of severe acute rejection, and demonstrated decreased global contraction. Group A hearts showed normal histology and contractility. However, thallium uptakes and washout of the two groups were the same. Peak thallium uptake of group B was +/- 3758 1166 counts compared with 3553 +/- 950 counts in the control group A (P = 0.6395); The 2-hr percentage of washout was 12.1 +/- 1.04 compared with 12.1 +/- 9.3 (P = 1.0000); and the decay constant was -0.00002065 +/- 0.00001799 compared with -0.00002202 +/- 0.00001508 (P = 0.8409). These data indicate that in vivo global thallium kinetics are preserved during mild-to-severe acute transplant rejection. These findings suggest that the complex cellular and extracellular processes of acute rejection limit the usefulness of thallium kinetics in the detection of acute transplant rejection

Spectral Filtering Criteria for U-Band Test Light for In-Service Line Monitoring in Optical Fiber Networks

Science.gov (United States)

Honda, Nazuki; Izumita, Hisashi; Nakamura, Minoru

2006-06-01

In the fiber-to-the-home era, thousands of optical fibers will have to be accommodated in the central offices of optical access networks. To reduce maintenance costs and improve the service reliability of optical fiber networks, the authors must develop an optical fiber line testing system with a function for in-service line monitoring that uses a test light with a wavelength different from the communication light wavelength. To monitor an in-service line in an optical network, the effective rejection ratio of the test light must be taken into account. This ratio depends on the spectrum of the test light from the optical time-domain reflectometer and the rejection band of the filter in front of the optical network unit. The dependence of the effective rejection ratio as a function of the sideband suppression ratio (SBSR) and of the ratio of the rejection band to the bandwidth of the sideband noise d/D is clarified. When d/D =0.1 and the target effective rejection ratio of the filter is -40 dB, the SBSR and the filter loss of the termination cable must be -70 and -43 dB, respectively, or the SBSR must be -80 dB. When d/D service line monitoring for a 10-Gb/s transmission using a 1650-nm test light with an SBSR of -80 dB is also demonstrated.

Robust sensor for turbidity measurement from light scattering and absorbing liquids.

Science.gov (United States)

Kontturi, Ville; Turunen, Petri; Uozumi, Jun; Peiponen, Kai-Erik

2009-12-01

Internationally standardized turbidity measurements for probing solid particles in liquid are problematic in the case of simultaneous light scattering and absorption. A method and a sensor to determine the turbidity in the presence of light absorption are presented. The developed sensor makes use of the total internal reflection of a laser beam at the liquid-prism interface, and the turbidity is assessed using the concept of laser speckle pattern. Using average filtering in speckle data analyzing the observed dynamic speckle pattern, which is due to light scattering from particles and the static speckle due to stray light of the sensor, can be separated from each other. Good correlation between the standard deviation of dynamic speckle and turbidity value for nonabsorbing and for absorbing liquids was observed. The sensor is suggested, for instance, for the measurement of ill-behaved as well as small-volume turbid liquids in both medicine and process industry.

Reject/repeat analysis and the effect prior film viewing has on a department's reject/repeat rate

International Nuclear Information System (INIS)

Clark, P.A.; Hogg, P.

2003-01-01

Purpose: Achieving cost-effectiveness within the NHS is an old initiative but one that has again been highlighted by recent government policies (The New NHS-Modern and Dependable, Stationary Office, London, 1997). It has been reiterated that it is the responsibility of individual Trusts to devise means to provide such a service. Reject/repeat analyses have long been the primary tool used to assess the cost-effectiveness of radiography departments (Quality Assurance in Diagnostic Radiology, WHO, Geneva, 1982). This research paper examines an in-house initiative (viewing patients' previous films) commonly employed in other Health Trusts in order to reduce departmental repeat/reject rates. Method: Three hundred orthopaedic patients with hip, knee and ankle prostheses were included in a reject/repeat analysis. The aim was to investigate whether or not viewing patient's previous relevant radiographs would be advantageous to the practicing radiographer. This was done through an audit cycle consisting of two audit periods each lasting for 3 months. The primary audit period recorded the baseline repeat/reject rate, with the secondary audit period recording the repeat/reject rate under an experimental condition of viewing the relevant radiographs. Results: The baseline audit revealed repeat rates of 33% in orthopaedic patients with hip, knee and ankle prostheses. The availability of prior film viewing to the radiographer reduced this repeat rate to 10.6%. Conclusion: Prior film viewing dramatically reduced the department's repeat/reject rate by 22.4%. This provides scope for significant patient dose reductions as well as reducing departmental film expenses. This is an underestimated initiative and should be used appropriately in routine clinical practice

Cell-Free DNA and Active Rejection in Kidney Allografts.

Science.gov (United States)

Bloom, Roy D; Bromberg, Jonathan S; Poggio, Emilio D; Bunnapradist, Suphamai; Langone, Anthony J; Sood, Puneet; Matas, Arthur J; Mehta, Shikha; Mannon, Roslyn B; Sharfuddin, Asif; Fischbach, Bernard; Narayanan, Mohanram; Jordan, Stanley C; Cohen, David; Weir, Matthew R; Hiller, David; Prasad, Preethi; Woodward, Robert N; Grskovic, Marica; Sninsky, John J; Yee, James P; Brennan, Daniel C

2017-07-01

Histologic analysis of the allograft biopsy specimen is the standard method used to differentiate rejection from other injury in kidney transplants. Donor-derived cell-free DNA (dd-cfDNA) is a noninvasive test of allograft injury that may enable more frequent, quantitative, and safer assessment of allograft rejection and injury status. To investigate this possibility, we prospectively collected blood specimens at scheduled intervals and at the time of clinically indicated biopsies. In 102 kidney recipients, we measured plasma levels of dd-cfDNA and correlated the levels with allograft rejection status ascertained by histology in 107 biopsy specimens. The dd-cfDNA level discriminated between biopsy specimens showing any rejection (T cell-mediated rejection or antibody-mediated rejection [ABMR]) and controls (no rejection histologically), P rejection at a cutoff of 1.0% dd-cfDNA were 61% and 84%, respectively. The AUC for discriminating ABMR from samples without ABMR was 0.87 (95% CI, 0.75 to 0.97). Positive and negative predictive values for ABMR at a cutoff of 1.0% dd-cfDNA were 44% and 96%, respectively. Median dd-cfDNA was 2.9% (ABMR), 1.2% (T cell-mediated types ≥IB), 0.2% (T cell-mediated type IA), and 0.3% in controls ( P =0.05 for T cell-mediated rejection types ≥IB versus controls). Thus, dd-cfDNA may be used to assess allograft rejection and injury; dd-cfDNA levels rejection (T cell-mediated type ≥IB or ABMR) and levels >1% indicate a probability of active rejection. Copyright © 2017 by the American Society of Nephrology.

An evaluation of safety guidelines to restrict exposure to stray radiofrequency radiation from short-wave diathermy units

Energy Technology Data Exchange (ETDEWEB)

Shields, Nora [School of Physiotherapy, La Trobe University, Victoria 3086 (Australia); O' Hare, Neil [Department of Medical Physics and Bioengineering, St James' s Hospital, Dublin 8 (Ireland); Gormley, John [School of Physiotherapy, Trinity College Dublin, Trinity Centre for Health Sciences, St James' s Hospital, Dublin 8 (Ireland)

2004-07-07

Short-wave diathermy (SWD), a form of radiofrequency radiation used therapeutically by physiotherapists, may be applied in continuous (CSWD) or pulsed (PSWD) mode using either capacitive or inductive methods. Stray radiation emitted by these units may exceed exposure guidelines close to the equipment. Discrepant guidelines exist on a safe distance from an operating unit for operators and other personnel. Stray electric (E-field) and magnetic (H-field) field strengths from 10 SWD units in six departments were examined using a PMM 8053 meter and two isotropic probes (EP-330, HP-032). A 5 l saline phantom completed the patient circuit. Measurements were recorded in eight directions between 0.5 m and 2 m at hip and eye levels while the units operated at maximum output and data compared to current guidelines. Results found stray fields from capacitive CSWD fell below operator limits at 2 m (E-field 4.8-39.8 V/m; H-field 0.015-0.072 A/m) and at 1 m for inductive CSWD (E-field 0-36 V/m; H-field 0.01-0.065 A/m). Capacitive PSWD fields fell below the limits at 1.5 m (E-field 1.2-19.9 V/m; H-field 0.002-0.045 A/m) and at 1m for inductive PSWD (E-field 0.7-4.0 V/m; H-field 0.009-0.03 A/m). An extra 0.5 m was required before fields fell below the guidelines for other personnel. These results demonstrate, under a worst case scenario, emissions from SWD exceed the guidelines for operators at distances currently recommended as safe. Future guidelines should include recommendations for personnel other than physiotherapists.

An evaluation of safety guidelines to restrict exposure to stray radiofrequency radiation from short-wave diathermy units

International Nuclear Information System (INIS)

Shields, Nora; O'Hare, Neil; Gormley, John

2004-01-01

Short-wave diathermy (SWD), a form of radiofrequency radiation used therapeutically by physiotherapists, may be applied in continuous (CSWD) or pulsed (PSWD) mode using either capacitive or inductive methods. Stray radiation emitted by these units may exceed exposure guidelines close to the equipment. Discrepant guidelines exist on a safe distance from an operating unit for operators and other personnel. Stray electric (E-field) and magnetic (H-field) field strengths from 10 SWD units in six departments were examined using a PMM 8053 meter and two isotropic probes (EP-330, HP-032). A 5 l saline phantom completed the patient circuit. Measurements were recorded in eight directions between 0.5 m and 2 m at hip and eye levels while the units operated at maximum output and data compared to current guidelines. Results found stray fields from capacitive CSWD fell below operator limits at 2 m (E-field 4.8-39.8 V/m; H-field 0.015-0.072 A/m) and at 1 m for inductive CSWD (E-field 0-36 V/m; H-field 0.01-0.065 A/m). Capacitive PSWD fields fell below the limits at 1.5 m (E-field 1.2-19.9 V/m; H-field 0.002-0.045 A/m) and at 1m for inductive PSWD (E-field 0.7-4.0 V/m; H-field 0.009-0.03 A/m). An extra 0.5 m was required before fields fell below the guidelines for other personnel. These results demonstrate, under a worst case scenario, emissions from SWD exceed the guidelines for operators at distances currently recommended as safe. Future guidelines should include recommendations for personnel other than physiotherapists

Peer victimization and peer rejection during early childhood

Science.gov (United States)

Godleski, Stephanie A.; Kamper, Kimberly E.; Ostrov, Jamie M.; Hart, Emily J.; Blakely-McClure, Sarah J.

2014-01-01

Objective The development and course of the subtypes of peer victimization is a relatively understudied topic despite the association of victimization with important developmental and clinical outcomes. Moreover, understanding potential predictors, such as peer rejection and emotion regulation, in early childhood may be especially important to elucidate possible bi-directional pathways between relational and physical victimization and rejection. The current study (N = 97) was designed to explore several gaps and limitations in the peer victimization and peer rejection literature. In particular, the prospective associations between relational and physical victimization and peer rejection over the course of 3.5 months during early childhood (i.e., 3- to 5- years-old) were investigated in an integrated model. Method The study consisted of 97 (42 girls) preschool children recruited from four early childhood schools in the northeast of the US. Using observations, research assistant report and teacher report, relational and physical aggression, relational and physical victimization, peer rejection, and emotion regulation were measured in a short-term longitudinal study. Path analyses were conducted to test the overall hypothesized model. Results Peer rejection was found to predict increases in relational victimization. In addition, emotion regulation was found to predict decreases in peer rejection and physical victimization. Conclusions Implications for research and practice are discussed, including teaching coping strategies for peer rejection and emotional distress. PMID:25133659

Understanding maladaptive responses to rejection: Aggression with an audience.

Science.gov (United States)

DeBono, Amber; Layton, Rebekah L; Freeman, Nicholas; Muraven, Mark

2017-01-01

Logically, responding aggressively to rejection is maladaptive because one is unlikely to seek a relationship with an aggressor. We predict that when concealed, the illogical aggressive response to rejection is more likely, whereas when the rejected individuals' aggressive responses are perceived as public, the aggressive acts may be reduced. Participants were rejected by others (Experiment 1) or were either accepted or rejected during an online ball-tossing game (Experiment 2) and were then given an opportunity to aggress publicly or privately. Across experiments, when the opportunity to aggress was made public, rejected participants exhibited less aggressive behavior. When concerned about the perception of their public aggressive responses by others, rejected individuals' aggressive responses diminished compared with those whose actions were private. Crucially, this extended to aggression visible only to neutral others, suggesting that effects cannot solely be due to fear of retribution.

Predicting outcome of acute kidney transplant rejection using

NARCIS (Netherlands)

Rekers, Niels Vincent

2014-01-01

Acute kidney transplant rejection is an important risk factors for adverse graft outcome. Once diagnosed, it remains difficult to predict the risk of graft loss and the response to anti-rejection treatment. The aim of this thesis was to identify biomarkers during acute rejection, which predict the

The Neural Basis of Recollection Rejection: Increases in Hippocampal-Prefrontal Connectivity in the Absence of a Shared Recall-to-Reject and Target Recollection Network.

Science.gov (United States)

Bowman, Caitlin R; Dennis, Nancy A

2016-08-01

Recollection rejection or "recall-to-reject" is a mechanism that has been posited to help maintain accurate memory by preventing the occurrence of false memories. Recollection rejection occurs when the presentation of a new item during recognition triggers recall of an associated target, a mismatch in features between the new and old items is registered, and the lure is correctly rejected. Critically, this characterization of recollection rejection involves a recall signal that is conceptually similar to recollection as elicited by a target. However, previous neuroimaging studies have not evaluated the extent to which recollection rejection and target recollection rely on a common neural signal but have instead focused on recollection rejection as a postretrieval monitoring process. This study utilized a false memory paradigm in conjunction with an adapted remember-know-new response paradigm that separated "new" responses based on recollection rejection from those that were based on a lack of familiarity with the item. This procedure allowed for parallel recollection rejection and target recollection contrasts to be computed. Results revealed that, contrary to predictions from theoretical and behavioral literature, there was virtually no evidence of a common retrieval mechanism supporting recollection rejection and target recollection. Instead of the typical target recollection network, recollection rejection recruited a network of lateral prefrontal and bilateral parietal regions that is consistent with the retrieval monitoring network identified in previous neuroimaging studies of recollection rejection. However, a functional connectivity analysis revealed a component of the frontoparietal rejection network that showed increased coupling with the right hippocampus during recollection rejection responses. As such, we demonstrate a possible link between PFC monitoring network and basic retrieval mechanisms within the hippocampus that was not revealed with

A survey of ectoparasite infestations in stray dogs of Gwang-ju City, Republic of Korea.

Science.gov (United States)

Chee, Jeong Hyun; Kwon, Jung Kee; Cho, Ho Seong; Cho, Kyoung Oh; Lee, Yu Jin; Abd El-Aty, A M; Abdel-Aty, A M; Shin, Sung Shik

2008-03-01

This study was designed to investigate the incidence of ectoparasite infestation among stray dogs in Gwang-ju City, Republic of Korea. A total of 103 stray dogs collected in the Animal Shelter of Gwang-ju City from November 2003 to August 2005 were investigated in this study. Ectoparasites of one or more genera were detected in 45.6% (47 / 103) of the dogs examined for dermatologic lesions and/or skin scrapings (from 3-5 affected areas). Otodectes cynotis was found to be the most frequent parasite (22.3%, 23 / 103), followed by Sarcoptes scabiei var canis (19.4%, 20 / 103), Ctenocephalides canis (6.8%, 7 / 103), Demodex canis (4.9%, 5 / 103), and Trichodectes canis (1.0%, 1 / 103). Monospecific infestation was found in 83.0% (39 / 47) of the affected dogs, whereas concurrent infestations with 2 or more ectoparasites per animal were found in 17.0% (8 / 47) of the affected dogs. Trichodectes canis is reported for the first time in the Republic of Korea. Dogs less than 1 yr old were more heavily infected than other age groups (66.7%), and small-sized dogs of less than 3 kg body weight were more heavily infected than larger dogs (41.7%).

Prevalence and characteristics of foal rejection in Arabian mares.

Science.gov (United States)

Juarbe-Díaz, S V; Houpt, K A; Kusunose, R

1998-09-01

Separate surveys of Thoroughbred, Paint, and Arabian mare owners revealed a higher than expected rate of foal rejection in Arabian mares. A behavioural history form was submitted by owners of foal rejecting and nonrejecting Arabian mares, and maternal behaviour and management practices compared. Four generation pedigrees of rejecting and nonrejecting Arabian mares were also examined. Foal rejecting mares were more likely to avoid, threaten, squeal at, chase, bite, and kick their foals post partum than nonrejecting mares. Nonrejecting mares were more likely to lick, nicker and defend their foals post partum than rejecting mares. No statistically significant relationship was found between foal rejection and the type of breeding method (natural vs. artificial insemination), the presence of people at birth, the presence of nearby horses at birth, or assistance of the first nursing bout. The presence at least once of 1 of 2 related sires was statistically higher in the pedigrees of rejecting vs. nonrejecting mares. Inherited and learned or environmental factors are likely to affect the expression of foal rejection behaviour.

Stomaching rejection: Self-compassion and self-esteem moderate the impact of daily social rejection on restrictive eating behaviours among college women.

Science.gov (United States)

Beekman, Janine B; Stock, Michelle L; Howe, George W

2017-11-01

The present study examined whether having high self-esteem or a self-compassionate perspective help mitigate the impact of daily social rejection on negative affect and restrictive eating behaviours. Following a baseline survey assessing self-esteem and self-compassion, 121 college women completed online daily diaries for one week. Negative affect and restrictive eating behaviours. On days when women reported more rejection, they also reported higher restrictive eating behaviours and greater negative affect. Effects were moderated by self-esteem and self-compassion, such that the lower participants were in self-esteem or self-compassion, the stronger the positive relation between rejection and negative affect and restrictive eating. However, only the common humanity/isolation dimension of self-compassion significantly moderated daily effects of rejection when controlling for self-esteem. Mediated moderation results reveal different mechanisms by which self-esteem and self-compassion buffer against rejections' effects on affect and restrictive eating. Self-compassion and self-esteem influence the complex impact that social rejection has on affect and restrictive eating. More than other dimensions of self-compassion or self-esteem, remembering one's common humanity can result in a healthier response to social rejection.

Measurement of stray radiation within a scanning proton therapy facility: EURADOS WG9 intercomparison exercise of active dosimetry systems

Czech Academy of Sciences Publication Activity Database

Farah, J.; Mares, V.; Romero-Exposito, M.; Trinkl, S.; Domingo, C.; Dufek, V.; Klodowska, M.; Kubančák, Ján; Knezevic, Z.; Ploc, Ondřej

2015-01-01

Roč. 42, č. 5 (2015), s. 2572-2584 ISSN 0094-2405 Institutional support: RVO:61389005 Keywords : scanning proton therapy * measurement of stray neutrons * spectrometry * ambient dose eyuivalent * intercomparison Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 2.496, year: 2015

Emotional, Cognitive and Self-Enhancement Processes in Aggressive Behavior After Interpersonal Rejection and Exclusion.

Science.gov (United States)

Rajchert, Joanna

2015-11-01

The relationship between exclusion or rejection and aggression is already well documented, but there is still a debate about the mechanisms that underlie this effect. In two studies we focused on the propensity to react aggressively (readiness for aggression) on the bases of emotional, cognitive or self-enhancement (personality-immanent) processes. In both studies we first measured readiness for aggression and then ego-depleted participants. Next, in Study 1 we excluded participants (n = 96) using an online ball throwing game and measured displaced aggressive behavior - intensity and duration of an unpleasant noise administrated to a stranger. In Study 2 participants (n = 140) were rejected by a peer on the basis of an interview that they gave and then could retaliate by reducing peer's chance for getting a job. The results show that exclusion effect on displaced aggression was moderated by cognitive readiness for aggression, while rejection effect on retaliatory aggression was shaped by emotional and personality-immanent readiness for aggression as well as ego-depletion. The results were discussed in light of the strength model of self-control by Baumeister, Vohs, and Tice (2007).

Emotional, Cognitive and Self-Enhancement Processes in Aggressive Behavior After Interpersonal Rejection and Exclusion

Directory of Open Access Journals (Sweden)

Joanna Rajchert

2015-11-01

Full Text Available The relationship between exclusion or rejection and aggression is already well documented, but there is still a debate about the mechanisms that underlie this effect. In two studies we focused on the propensity to react aggressively (readiness for aggression on the bases of emotional, cognitive or self-enhancement (personality-immanent processes. In both studies we first measured readiness for aggression and then ego-depleted participants. Next, in Study 1 we excluded participants (n = 96 using an online ball throwing game and measured displaced aggressive behavior - intensity and duration of an unpleasant noise administrated to a stranger. In Study 2 participants (n = 140 were rejected by a peer on the basis of an interview that they gave and then could retaliate by reducing peer's chance for getting a job. The results show that exclusion effect on displaced aggression was moderated by cognitive readiness for aggression, while rejection effect on retaliatory aggression was shaped by emotional and personality-immanent readiness for aggression as well as ego-depletion. The results were discussed in light of the strength model of self-control by Baumeister, Vohs, and Tice (2007.

Laughter as a social rejection cue: Influence of prior explicit experience of social rejection on cardiac signs of "freezing".

Science.gov (United States)

Lackner, Helmut K; Reiter-Scheidl, Katharina; Aydin, Nilüfer; Perchtold, Corinna M; Weiss, Elisabeth M; Papousek, Ilona

2018-06-01

The study aimed at investigating the immediate cardiac effect of the sudden perception of other people's laughter after experimentally manipulating healthy participants' proneness to experience laughter as a cue of social threat. We expected that participants would show cardiac signs of freezing (i.e., sustained heart rate deceleration immediately after perception of the laughter) after prior social rejection but not or less so after prior acceptance, due to an increased bias to perceive the ambiguous social signal as a cue of social threat and rejection after rejection had been primed. Contrary to expectations, the perception of other people's laughter elicited a decelerative (freezing) response regardless of whether it was preceded by the experience of social rejection or acceptance. The response was prolonged in participants who had been accepted beforehand compared to those who had been rejected. The findings indicate that, given a relevant social context, other people's laughter can be a powerful cue of social threat and rejection also in healthy individuals. Prolonged heart rate deceleration after an ambiguous social signal may facilitate the processing of significant social information in the socially threatening situation. The study adds to the literature rendering the course of the immediate transient heart rate response a useful tool in social rejection research. Additionally, the findings suggested that in some cases the further progress of transient heart rate changes in more extended time-windows (about 30 s) may provide additional relevant information about the processing of social cues. Copyright © 2018 Elsevier B.V. All rights reserved.

Detection of cardiac transplant rejection with radiolabeled lymphocytes

International Nuclear Information System (INIS)

Bergmann, S.R.; Lerch, R.A.; Carlson, E.M.; Saffitz, J.E.; Sobel, B.E.

1982-01-01

To determine whether rejections of cardiac transplants could be detected specifically and non-invasively by lymphocytes labeled with indium-111 (111In), we studied 36 allogeneic and 14 isogeneic heterotopic cardiac transplants in rats. Allogeneic grafts accumulated autologous 111In-lymphocytes, detectable scintigraphically 24 hours after i.v. injection of the labeled cells. At the time of peak histologic rejection, the allogeneic grafts accumulated 92. +/- 4.8 times more activity than the native hearts (determined by well counting). The tissue-to-blood ratio in the rejecting transplants was 3.7 +/- 2.2; total uptake by the graft was 2.9 +/- 2.1% of the injected dose. Autoradiography confirmed that graft radioactivity was associated with labeled lymphocytes. In contrast, isogeneic grafts showed no signs of rejection and did not accumulate radioactivity. Because conventionally isolated and labeled lymphocytes are often contaminated with platelets, we prepared both 111In-platelets and purified 111In-lymphocytes for use in additional experiments. Allogeneic grafts accumulated platelets and purified lymphocytes independently. Thus, deposition of immunologically active cells in the rejecting graft representing specific pathophysiologic events can be detected. The results suggest that rejection of cardiac transplants can be detected noninvasively, potentially facilitating objective early clinical detection of rejection and titration of antirejection therapy

Digital pile-up rejection for plutonium experiments with solution-grown stilbene

Energy Technology Data Exchange (ETDEWEB)

Bourne, M.M., E-mail: mmbourne@umich.edu; Clarke, S.D., E-mail: clarkesd@umich.edu; Paff, M., E-mail: mpaff@umich.edu; DiFulvio, A., E-mail: difulvio@umich.edu; Norsworthy, M., E-mail: marknors@umich.edu; Pozzi, S.A., E-mail: pozzisa@umich.edu

2017-01-11

A solution-grown stilbene detector was used in several experiments with plutonium samples including plutonium oxide, mixed oxide, and plutonium metal samples. Neutrons from different reactions and plutonium isotopes are accompanied by numerous gamma rays especially by the 59-keV gamma ray of {sup 241}Am. Identifying neutrons correctly is important for nuclear nonproliferation applications and makes neutron/gamma discrimination and pile-up rejection necessary. Each experimental dataset is presented with and without pile-up filtering using a previously developed algorithm. The experiments were simulated using MCNPX-PoliMi, a Monte Carlo code designed to accurately model scintillation detector response. Collision output from MCNPX-PoliMi was processed using the specialized MPPost post-processing code to convert neutron energy depositions event-by-event into light pulses. The model was compared to experimental data after pulse-shape discrimination identified waveforms as gamma ray or neutron interactions. We show that the use of the digital pile-up rejection algorithm allows for accurate neutron counting with stilbene to within 2% even when not using lead shielding.

Optimization of the occulter for the Solar Orbiter/METIS coronagraph

Science.gov (United States)

Landini, Federico; Vivès, Sébastien; Romoli, Marco; Guillon, Christophe; Pancrazzi, Maurizio; Escolle, Clement; Focardi, Mauro; Antonucci, Ester; Fineschi, Silvano; Naletto, Giampiero; Nicolini, Gianalfredo; Nicolosi, Piergiorgio; Spadaro, Daniele

2012-09-01

METIS (Multi Element Telescope for Imaging and Spectroscopy investigation), selected to fly aboard the Solar Orbiter ESA/NASA mission, is conceived to perform imaging (in visible, UV and EUV) and spectroscopy (in EUV) of the solar corona, by means of an integrated instrument suite located on a single optical bench and sharing the same aperture on the satellite heat shield. As every coronagraph, METIS is highly demanding in terms of stray light suppression. Coronagraphs history teaches that a particular attention must be dedicated to the occulter optimization. The METIS occulting system is of particular interest due to its innovative concept. In order to meet the strict thermal requirements of Solar Orbiter, METIS optical design has been optimized by moving the entrance pupil at the level of the external occulter on the S/C thermal shield, thus reducing the size of the external aperture. The scheme is based on an inverted external-occulter (IEO). The IEO consists of a circular aperture on the Solar Orbiter thermal shield. A spherical mirror rejects back the disk-light through the IEO. A breadboard of the occulting assembly (BOA) has been manufactured in order to perform stray light tests in front of two solar simulators (in Marseille, France and in Torino, Italy). A first measurement campaign has been carried on at the Laboratoire d'Astrophysique de Marseille. In this paper we describe the BOA design, the laboratory set-up and the preliminary results.

High-testosterone men reject low ultimatum game offers.

Science.gov (United States)

Burnham, Terence C

2007-09-22

The ultimatum game is a simple negotiation with the interesting property that people frequently reject offers of 'free' money. These rejections contradict the standard view of economic rationality. This divergence between economic theory and human behaviour is important and has no broadly accepted cause. This study examines the relationship between ultimatum game rejections and testosterone. In a variety of species, testosterone is associated with male seeking dominance. If low ultimatum game offers are interpreted as challenges, then high-testosterone men may be more likely to reject such offers. In this experiment, men who reject low offers ($5 out of $40) have significantly higher testosterone levels than those who accept. In addition, high testosterone levels are associated with higher ultimatum game offers, but this second finding is not statistically significant.

21 CFR 1230.47 - Rejected containers.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Rejected containers. 1230.47 Section 1230.47 Food... FEDERAL CAUSTIC POISON ACT Imports § 1230.47 Rejected containers. (a) In all cases where the containers... notification to the importer that the containers must be exported under customs supervision within 3 months...

Image rejects in general direct digital radiography

International Nuclear Information System (INIS)

Hofmann, Bjørn; Rosanowsky, Tine Blomberg; Jensen, Camilla; Wah, Kenneth Hong Ching

2015-01-01

The number of rejected images is an indicator of image quality and unnecessary imaging at a radiology department. Image reject analysis was frequent in the film era, but comparably few and small studies have been published after converting to digital radiography. One reason may be a belief that rejects have been eliminated with digitalization. To measure the extension of deleted images in direct digital radiography (DR), in order to assess the rates of rejects and unnecessary imaging and to analyze reasons for deletions, in order to improve the radiological services. All exposed images at two direct digital laboratories at a hospital in Norway were reviewed in January 2014. Type of examination, number of exposed images, and number of deleted images were registered. Each deleted image was analyzed separately and the reason for deleting the image was recorded. Out of 5417 exposed images, 596 were deleted, giving a deletion rate of 11%. A total of 51.3% were deleted due to positioning errors and 31.0% due to error in centering. The examinations with the highest percentage of deleted images were the knee, hip, and ankle, 20.6%, 18.5%, and 13.8% respectively. The reject rate is at least as high as the deletion rate and is comparable with previous film-based imaging systems. The reasons for rejection are quite different in digital systems. This falsifies the hypothesis that digitalization would eliminates rejects. A deleted image does not contribute to diagnostics, and therefore is an unnecessary image. Hence, the high rates of deleted images have implications for management, training, education, as well as for quality

Image rejects in general direct digital radiography.

Science.gov (United States)

Hofmann, Bjørn; Rosanowsky, Tine Blomberg; Jensen, Camilla; Wah, Kenneth Hong Ching

2015-10-01

The number of rejected images is an indicator of image quality and unnecessary imaging at a radiology department. Image reject analysis was frequent in the film era, but comparably few and small studies have been published after converting to digital radiography. One reason may be a belief that rejects have been eliminated with digitalization. To measure the extension of deleted images in direct digital radiography (DR), in order to assess the rates of rejects and unnecessary imaging and to analyze reasons for deletions, in order to improve the radiological services. All exposed images at two direct digital laboratories at a hospital in Norway were reviewed in January 2014. Type of examination, number of exposed images, and number of deleted images were registered. Each deleted image was analyzed separately and the reason for deleting the image was recorded. Out of 5417 exposed images, 596 were deleted, giving a deletion rate of 11%. A total of 51.3% were deleted due to positioning errors and 31.0% due to error in centering. The examinations with the highest percentage of deleted images were the knee, hip, and ankle, 20.6%, 18.5%, and 13.8% respectively. The reject rate is at least as high as the deletion rate and is comparable with previous film-based imaging systems. The reasons for rejection are quite different in digital systems. This falsifies the hypothesis that digitalization would eliminates rejects. A deleted image does not contribute to diagnostics, and therefore is an unnecessary image. Hence, the high rates of deleted images have implications for management, training, education, as well as for quality.

Specimen rejection in laboratory medicine: Necessary for patient safety?

Science.gov (United States)

Dikmen, Zeliha Gunnur; Pinar, Asli; Akbiyik, Filiz

2015-01-01

The emergency laboratory in Hacettepe University Hospitals receives specimens from emergency departments (EDs), inpatient services and intensive care units (ICUs). The samples are accepted according to the rejection criteria of the laboratory. In this study, we aimed to evaluate the sample rejection ratios according to the types of pre-preanalytical errors and collection areas. The samples sent to the emergency laboratory were recorded during 12 months between January to December, 2013 in which 453,171 samples were received and 27,067 specimens were rejected. Rejection ratios was 2.5% for biochemistry tests, 3.2% for complete blood count (CBC), 9.8% for blood gases, 9.2% for urine analysis, 13.3% for coagulation tests, 12.8% for therapeutic drug monitoring, 3.5% for cardiac markers and 12% for hormone tests. The most frequent rejection reasons were fibrin clots (28%) and inadequate volume (9%) for biochemical tests. Clotted samples (35%) and inadequate volume (13%) were the major causes for coagulation tests, blood gas analyses and CBC. The ratio of rejected specimens was higher in the EDs (40%) compared to ICUs (30%) and inpatient services (28%). The highest rejection ratio was observed in neurology ICU (14%) among the ICUs and internal medicine inpatient service (10%) within inpatient clinics. We detected an overall specimen rejection rate of 6% in emergency laboratory. By documentation of rejected samples and periodic training of healthcare personnel, we expect to decrease sample rejection ratios below 2%, improve total quality management of the emergency laboratory and promote patient safety.

Corneal allograft rejection: Risk factors, diagnosis, prevention, and treatment

Directory of Open Access Journals (Sweden)

Dua Harminder

1999-01-01

Full Text Available Recent advances in corneal graft technology, including donor tissue retrieval, storage and surgical techniques, have greatly improved the clinical outcome of corneal grafts. Despite these advances, immune mediated corneal graft rejection remains the single most important cause of corneal graft failure. Several host factors have been identified as conferring a "high risk" status to the host. These include: more than two quadrant vascularisation, with associated lymphatics, which augment the afferent and efferent arc of the immune response; herpes simplex keratitis; uveitis; silicone oil keratopathy; previous failed (rejected grafts; "hot eyes"; young recipient age; and multiple surgical procedures at the time of grafting. Large grafts, by virtue of being closer to the host limbus, with its complement of vessels and antigen-presenting Langerhans cells, also are more susceptible to rejection. The diagnosis of graft rejection is entirely clinical and in its early stages the clinical signs could be subtle. Graft rejection is largely mediated by the major histocompatibility antigens, minor antigens and perhaps blood group ABO antigens and some cornea-specific antigens. Just as rejection is mediated by active immune mediated events, the lack of rejection (tolerance is also sustained by active immune regulatory mechanisms. The anterior chamber associated immune deviation (ACAID and probably, conjunctiva associated lymphoid tissue (CALT induced mucosal tolerance, besides others, play an important role. Although graft rejection can lead to graft failure, most rejections can be readily controlled if appropriate management is commenced at the proper time. Topical steroids are the mainstay of graft rejection management. In the high-risk situations however, systemic steroids, and other immunosuppressive drugs such as cyclosporin and tacrolimus (FK506 are of proven benefit, both for treatment and prevention of rejection.

Graft rejection by cytolytic T cells. Specificity of the effector mechanism in the rejection of allogeneic marrow

International Nuclear Information System (INIS)

Nakamura, H.; Gress, R.E.

1990-01-01

Cellular effector mechanisms of allograft rejection remain incompletely described. Characterizing the rejection of foreign-marrow allografts rather than solid-organ grafts has the advantage that the cellular composition of the marrow graft, as a single cell suspension, can be altered to include cellular components with differing antigen expression. Rejection of marrow grafts is sensitive to lethal doses of radiation in the mouse but resistant to sublethal levels of radiation. In an effort to identify cells mediating host resistance, lymphocytes were isolated and cloned from spleens of mice 7 days after sublethal TBI (650 cGy) and inoculation with allogeneic marrow. All clones isolated were cytolytic with specificity for MHC encoded gene products of the allogeneic marrow donor. When cloned cells were transferred in vivo into lethally irradiated (1025 cGy) recipients unable to reject allogeneic marrow, results utilizing splenic 125IUdR uptake indicated that these MHC-specific cytotoxic clones could suppress marrow proliferation. In order to characterize the effector mechanism and the ability of the clones to affect final engraftment, double donor chimeras were constructed so that 2 target cell populations differing at the MHC from each other and from the host were present in the same marrow allograft. Results directly demonstrated an ability of CTL of host MHC type to mediate graft rejection and characterized the effector mechanism as one with specificity for MHC gene products

Diagnosis of cardiac allograft rejection with MR imaging

International Nuclear Information System (INIS)

Soulen, R.L.; Fraser, C.D.; Hutchins, G.M.; Baumgartner, W.A.; Reitz, B.A.

1987-01-01

Serial MR images and endomyocardial biopsy specimens of heterotopic cervical cardiac allotransplants were obtained in six dogs during 2 weeks of immunosuppression followed by 1 week without such therapy. A surface coil and gated spin-echo technique were used. Myocardial intensity (MI) measurements and histopathologic interpretations were performed independently. All six dogs showed a decrease in MI between their first and second MR studies, while showing no rejection. One dog had no rejection and died; in five dogs studies gated to every other beat showed progressive increase in MI that correlated significantly with increasing rejection, though absolute MI values did not correlated with a specific biopsy score. Severe rejection also caused overt increase in myocardial mass. The MI in the early postoperative period may reflect reperfusion injury. Absolute intensity values cannot predict rejection. Serial studies in transplant patients may prove clinically useful

Stray dogs as indicators of Toxoplasma gondii distributed in the environment: the first report across an urban-rural gradient in China

Directory of Open Access Journals (Sweden)

Yan Chao

2012-01-01

Full Text Available Abstract Background Toxoplasmosis is an important parasitic zoonosis caused by the protozoan Toxoplasma gondii that is distributed world-wide and infects a variety of hosts. However, the prevalence of T. gondii in the environment (such as soil, water and food is largely unknown. Due to the technical difficulty in oocyst counting directly, an alternative assay using the serologic status of T. gondii in free-living animals, such as stray or free-living dogs, as an indicator, can be used to evaluate environmental contamination indirectly, as they are exposed to the same risk of infection as humans and other animals. Results In the present study, 231 stray or free-living dogs across an urban-rural gradient were examined to assess the frequency of T. gondii in the environment. Specific antibodies to T. gondii were found in 93 dogs (40.3% by enzyme-linked immunosorbent assay (ELISA, and no statistically significant differences were observed in seroprevalences of T. gondii between urban dogs (38.7% and rural dogs (41% (p > 0.05. Conclusions A high seroprevalence of T. gondii in stray or free-living dogs in the present study indicates that there would be a wide distribution and a constant infection pressure of T. gondii across an urban-rural gradient, and the oocysts of T. gondii in the environment would be an important source of infection for humans and other animals both in urban and rural areas in China.

ERROR VS REJECTION CURVE FOR THE PERCEPTRON

OpenAIRE

PARRONDO, JMR; VAN DEN BROECK, Christian

1993-01-01

We calculate the generalization error epsilon for a perceptron J, trained by a teacher perceptron T, on input patterns S that form a fixed angle arccos (J.S) with the student. We show that the error is reduced from a power law to an exponentially fast decay by rejecting input patterns that lie within a given neighbourhood of the decision boundary J.S = 0. On the other hand, the error vs. rejection curve epsilon(rho), where rho is the fraction of rejected patterns, is shown to be independent ...

Rejection of Bromide and Bromate Ions by a Ceramic Membrane.

Science.gov (United States)

Moslemi, Mohammadreza; Davies, Simon H; Masten, Susan J

2012-12-01

Effects of pH and the addition of calcium chloride (CaCl(2)) on bromate (BrO(3) (-)) and bromide (Br(-)) rejection by a ceramic membrane were investigated. Rejection of both ions increased with pH. At pH 8, the rejection of BrO(3) (-) and Br(-) was 68% and 63%, respectively. Donnan exclusion appears to play an important role in determining rejection of BrO(3) (-) and Br(-). In the presence of CaCl(2), rejection of BrO(3) (-) and Br(-) ions was greatly reduced, confirming the importance of electrostatic interactions in determining rejection of BrO(3) (-) and Br(-). The effect of Ca(2+) is so pronounced that in most natural waters, rejection of both BrO(3) (-) and Br(-) by the membrane would be extremely small.

A Longitudinal Study of Rejecting and Autonomy-Restrictive Parenting, Rejection Sensitivity, and Socioemotional Symptoms in Early Adolescents.

Science.gov (United States)

Rowe, Susan L; Gembeck, Melanie J Zimmer; Rudolph, Julia; Nesdale, Drew

2015-08-01

Rejection sensitivity (RS) has been defined as the tendency to readily perceive and overreact to interpersonal rejection. The primary aim of this study was to test key propositions of RS theory, namely that rejecting experiences in relationships with parents are antecedents of early adolescents' future RS and symptomatology. We also expanded this to consider autonomy-restrictive parenting, given the importance of autonomy in early adolescence. Participants were 601 early adolescents (age 9 to 13 years old, 51% boys) from three schools in Australia. Students completed questionnaires at school about parent and peer relationships, RS, loneliness, social anxiety, and depression at two times with a 14-month lag between assessments. Parents also reported on adolescents' difficulties at Time 1 (T1). It was anticipated that more experience of parental rejection, coercion, and psychological control would be associated with adolescents' escalating RS and symptoms over time, even after accounting for peer victimisation, and that RS would mediate associations between parenting and symptoms. Structural equation modelling supported these hypotheses. Parent coercion was associated with adolescents' increasing symptoms of social anxiety and RS over time, and parent psychological control was associated with increasing depressive symptoms over time. Indirect effects via RS were also found, with parent rejection and psychological control linked to higher T1 RS, which was then associated with increasing loneliness and RS. Lastly, in a separate model, peer victimisation and RS, but not parenting practices, were positively associated with concurrent parent reports of adolescents' difficulties.

SU-E-T-598: Parametric Equation for Quick and Reliable Estimate of Stray Neutron Doses in Proton Therapy and Application for Intracranial Tumor Treatments

Energy Technology Data Exchange (ETDEWEB)

Bonfrate, A; Farah, J; Sayah, R; Clairand, I [Institut de Radioprotection et de Surete Nucleaire (IRSN), Fontenay-aux-roses (France); De Marzi, L; Delacroix, S [Institut Curie Centre de Protontherapie d Orsay (CPO), Orsay (France); Herault, J [Centre Antoine Lacassagne (CAL) Cyclotron biomedical, Nice (France); Lee, C [National Cancer Institute, Rockville, MD (United States); Bolch, W [Univ Florida, Gainesville, FL (United States)

2015-06-15

Purpose: Development of a parametric equation suitable for a daily use in routine clinic to provide estimates of stray neutron doses in proton therapy. Methods: Monte Carlo (MC) calculations using the UF-NCI 1-year-old phantom were exercised to determine the variation of stray neutron doses as a function of irradiation parameters while performing intracranial treatments. This was done by individually changing the proton beam energy, modulation width, collimator aperture and thickness, compensator thickness and the air gap size while their impact on neutron doses were put into a single equation. The variation of neutron doses with distance from the target volume was also included in it. Then, a first step consisted in establishing the fitting coefficients by using 221 learning data which were neutron absorbed doses obtained with MC simulations while a second step consisted in validating the final equation. Results: The variation of stray neutron doses with irradiation parameters were fitted with linear, polynomial, etc. model while a power-law model was used to fit the variation of stray neutron doses with the distance from the target volume. The parametric equation fitted well MC simulations while establishing fitting coefficients as the discrepancies on the estimate of neutron absorbed doses were within 10%. The discrepancy can reach ∼25% for the bladder, the farthest organ from the target volume. Finally, the validation showed results in compliance with MC calculations since the discrepancies were also within 10% for head-and-neck and thoracic organs while they can reach ∼25%, again for pelvic organs. Conclusion: The parametric equation presents promising results and will be validated for other target sites as well as other facilities to go towards a universal method.

Controlling trapping potentials and stray electric fields in a microfabricated ion trap through design and compensation

International Nuclear Information System (INIS)

Charles Doret, S; Amini, Jason M; Wright, Kenneth; Volin, Curtis; Killian, Tyler; Ozakin, Arkadas; Denison, Douglas; Hayden, Harley; Pai, C-S; Slusher, Richart E; Harter, Alexa W

2012-01-01

Recent advances in quantum information processing with trapped ions have demonstrated the need for new ion trap architectures capable of holding and manipulating chains of many (>10) ions. Here we present the design and detailed characterization of a new linear trap, microfabricated with scalable complementary metal-oxide-semiconductor (CMOS) techniques, that is well-suited to this challenge. Forty-four individually controlled dc electrodes provide the many degrees of freedom required to construct anharmonic potential wells, shuttle ions, merge and split ion chains, precisely tune secular mode frequencies, and adjust the orientation of trap axes. Microfabricated capacitors on dc electrodes suppress radio-frequency pickup and excess micromotion, while a top-level ground layer simplifies modeling of electric fields and protects trap structures underneath. A localized aperture in the substrate provides access to the trapping region from an oven below, permitting deterministic loading of particular isotopic/elemental sequences via species-selective photoionization. The shapes of the aperture and radio-frequency electrodes are optimized to minimize perturbation of the trapping pseudopotential. Laboratory experiments verify simulated potentials and characterize trapping lifetimes, stray electric fields, and ion heating rates, while measurement and cancellation of spatially-varying stray electric fields permits the formation of nearly-equally spaced ion chains. (paper)

Review: The transcripts associated with organ allograft rejection.

Science.gov (United States)

Halloran, Philip F; Venner, Jeffery M; Madill-Thomsen, Katelynn S; Einecke, Gunilla; Parkes, Michael D; Hidalgo, Luis G; Famulski, Konrad S

2018-04-01

The molecular mechanisms operating in human organ transplant rejection are best inferred from the mRNAs expressed in biopsies because the corresponding proteins often have low expression and short half-lives, while small non-coding RNAs lack specificity. Associations should be characterized in a population that rigorously identifies T cell-mediated (TCMR) and antibody-mediated rejection (ABMR). This is best achieved in kidney transplant biopsies, but the results are generalizable to heart, lung, or liver transplants. Associations can be universal (all rejection), TCMR-selective, or ABMR-selective, with universal being strongest and ABMR-selective weakest. Top universal transcripts are IFNG-inducible (eg, CXCL11 IDO1, WARS) or shared by effector T cells (ETCs) and NK cells (eg, KLRD1, CCL4). TCMR-selective transcripts are expressed in activated ETCs (eg, CTLA4, IFNG), activated (eg, ADAMDEC1), or IFNG-induced macrophages (eg, ANKRD22). ABMR-selective transcripts are expressed in NK cells (eg, FGFBP2, GNLY) and endothelial cells (eg, ROBO4, DARC). Transcript associations are highly reproducible between biopsy sets when the same rejection definitions, case mix, algorithm, and technology are applied, but exact ranks will vary. Previously published rejection-associated transcripts resemble universal and TCMR-selective transcripts due to incomplete representation of ABMR. Rejection-associated transcripts are never completely rejection-specific because they are shared with the stereotyped response-to-injury and innate immunity. © 2017 The American Society of Transplantation and the American Society of Transplant Surgeons.

Uptake of myocardial imaging agents by rejected hearts

International Nuclear Information System (INIS)

Bergsland, J.; Carr, E.A.; Carroll, M.; Wright, J.W.; Feldman, M.J.; Massucci, J.; Bhayana, J.N.; Gona, J.M.

1985-01-01

Technetium 99 m pyrophosphate, Gallium 67 and Thallium 201 uptakes were measured in heterotopically transplanted rat hearts. Five days after transplantation, Technetium 99 m pyrophosphate, and Gallium 67 uptakes were significantly higher in allogeneic grafts than in syngeneic grafts. At an early stage of rejection (three days after transplantation), only Technetium 99 m pyrophosphate uptake in the left ventricle of allogeneic grafts showed a significant difference (p less than 0.04). At five days, Thallium 201 uptake was significantly lower in allo- than syngeneic grafts. There was a positive correlation between radionuclide uptake and histologic degree of rejection for Technetium 99 m pyrophosphate and Gallium 67 while Thallium 201 uptake correlated negatively. Analysis of variance revealed that hearts with no or minimal rejection had statistically different uptakes than hearts with mild to moderate rejection. These results suggest that uptake of imaging agents might be useful in the diagnosis of rejection of the transplanted heart

Stray field signatures of Néel textured skyrmions in Ir/Fe/Co/Pt multilayer films

Science.gov (United States)

Yagil, A.; Almoalem, A.; Soumyanarayanan, Anjan; Tan, Anthony K. C.; Raju, M.; Panagopoulos, C.; Auslaender, O. M.

2018-05-01

Skyrmions are nanoscale spin configurations with topological properties that hold great promise for spintronic devices. Here, we establish their Néel texture, helicity, and size in Ir/Fe/Co/Pt multilayer films by constructing a multipole expansion to model their stray field signatures and applying it to magnetic force microscopy images. Furthermore, the demonstrated sensitivity to inhomogeneity in skyrmion properties, coupled with a unique capability to estimate the pinning force governing dynamics, portend broad applicability in the burgeoning field of topological spin textures.

Comparison of Sociometrically High Visibility Rejected and Low Visibility Rejected Children on Teacher, Parent, and Self-Rating Measures.

Science.gov (United States)

Neighbor, Jonelle C.

The study looked at differences between groups of children identified as high visibility rejected (HVR) and low visibility rejected (LVR) on a sociometric measure with 952 fourth, fifth, and sixth grade students. Questionnaires were analyzed to determine the number of positive and negative nominations from peers received by each child. HVR…

Pulmonary Mycobacterium tuberculosis (Beijing strain infection in a stray dog : clinical communication

Directory of Open Access Journals (Sweden)

S.D.C. Parsons

2008-05-01

Full Text Available Mycobacterium tuberculosis infection in dogs is rarely reported and has not previously been documented in South Africa. A case of a stray Maltese crossbreed dog with extensive multifocal pulmonary tuberculosis due to M. tuberculosis is described. Pulmonary granulomas in this case were poorly encapsulated and contained large numbers of acid-fast bacteria, highlighting the potential for infected companion animals to excrete the pathogen. Treatment of canine tuberculosis is generally not advised, and for this reason, euthanasia of diseased animals must be advocated in most instances. Physicians and veterinarians must be aware that companion animals with active disease caused by M. tuberculosis could act as a potential source of infection.

Molecular and serological surveillance of canine enteric viruses in stray dogs from Vila do Maio, Cape Verde.

Science.gov (United States)

Castanheira, Pedro; Duarte, Ana; Gil, Solange; Cartaxeiro, Clara; Malta, Manuel; Vieira, Sara; Tavares, Luis

2014-04-23

Infections caused by canine parvovirus, canine distemper virus and canine coronavirus are an important cause of mortality and morbidity in dogs worldwide. Prior to this study, no information was available concerning the incidence and prevalence of these viruses in Cape Verde archipelago. To provide information regarding the health status of the canine population in Vila do Maio, Maio Island, Cape Verde, 53 rectal swabs were collected from 53 stray dogs during 2010 and 93 rectal swabs and 88 blood samples were collected from 125 stray dogs in 2011. All rectal swabs (2010 n = 53; 2011 n = 93) were analysed for the presence of canine parvovirus, canine distemper virus and canine coronavirus nucleic acids by quantitative PCR methods. Specific antibodies against canine distemper virus and canine parvovirus were also assessed (2011 n = 88).From the 2010 sampling, 43.3% (23/53) were positive for canine parvovirus DNA, 11.3% (6/53) for canine distemper virus RNA and 1.9% (1/53) for canine coronavirus RNA. In 2011, the prevalence values for canine parvovirus and canine coronavirus were quite similar to those from the previous year, respectively 44.1% (41/93), and 1.1% (1/93), but canine distemper virus was not detected in any of the samples analysed (0%, 0/93). Antibodies against canine parvovirus were detected in 71.6% (63/88) blood samples and the seroprevalence found for canine distemper virus was 51.1% (45/88). This study discloses the data obtained in a molecular and serological epidemiological surveillance carried out in urban populations of stray and domestic animals. Virus transmission and spreading occurs easily in large dog populations leading to high mortality rates particularly in unvaccinated susceptible animals. In addition, these animals can act as disease reservoirs for wild animal populations by occasional contact. Identification of susceptible wildlife of Maio Island is of upmost importance to evaluate the risk of pathogen spill over from

Prediction of acute cardiac rejection using radionuclide techniques

International Nuclear Information System (INIS)

Novitzky, D.; Bonioszczuk, J.; Cooper, D.K.C.; Isaacs, S.; Rose, A.G.; Smith, J.A.; Uys, C.J.; Barnard, C.N.; Fraser, R.

1984-01-01

Radionuclide scanning of the donor left ventricle using technetium-99m-labelled red cells was used to monitor acute rejection after heterotopic heart transplantation and compared with histopathological evidence of rejection obtained at examination of an endomyocardial biopsy specimen. The ejection fraction and end-diastolic, end-systolic and stroke volumes were calculated at each examination; an equation was derived from these data to predict the degree of acute rejection, using histopathological examination of endomyocardial biopsy specimens as criteria of the presence and severity of rejection. A highly significant multiple correlation between radionuclide scanning parameters and endomyocardial biopsy was found. The advantages of non-invasive radionuclide scanning over the invasive procedure of endomyocardial biopsy are discussed

Enabling Junction Temperature Estimation via Collector-Side Thermo-Sensitive Electrical Parameters through Emitter Stray Inductance in High-Power IGBT Modules

DEFF Research Database (Denmark)

Luo, Haoze; Li, Wuhua; Iannuzzo, Francesco

2018-01-01

This paper proposes the adoption of the inherent emitter stray inductance LeE in high-power insulated gate bipolar transistor (IGBT) modules as a new dynamic thermo-sensitive electrical parameter (d-TSEP). Furthermore, a family of 14 derived dynamic TSEP candidates has been extracted and classified...

Donor-specific rejection: Clinical and scan correlation

International Nuclear Information System (INIS)

Wilson, M.A.; Mehta, R.C.; Perlman, S.B.; Servilla, K.; Sollinger, H.W.; Deierhoi, M.H.; Belzer, F.O.

1986-01-01

All 470 scans on 132 consecutive renal transplantation patients were reviewed. Scan patterns identified included acute tubular necrosis and conventional rejection. A new pattern, donor specific rejection (DSR), was identified in 24 of 42 patients on the living related donor specific transfusion (DST) protocol. This was characterized by good perfusion and extraction but significant renal stasis of tracer. This pattern was unique to the DST recipients and improved with antirejection therapy. The clinical features (incidence, temporal onset) and severity (duration, serum creatinines) are compared in these patient populations. DSR occurs more frequently than conventional rejection but is a milder process

Allorecognition pathways in transplant rejection and tolerance.

Science.gov (United States)

Ali, Jason M; Bolton, Eleanor M; Bradley, J Andrew; Pettigrew, Gavin J

2013-10-27

With the advent of cellular therapies, it has become clear that the success of future therapies in prolonging allograft survival will require an intimate understanding of the allorecognition pathways and effector mechanisms that are responsible for chronic rejection and late graft loss.Here, we consider current understanding of T-cell allorecognition pathways and discuss the most likely mechanisms by which these pathways collaborate with other effector mechanisms to cause allograft rejection. We also consider how this knowledge may inform development of future strategies to prevent allograft rejection.Although both direct and indirect pathway CD4 T cells appear active immediately after transplantation, it has emerged that indirect pathway CD4 T cells are likely to be the dominant alloreactive T-cell population late after transplantation. Their ability to provide help for generating long-lived alloantibody is likely one of the main mechanisms responsible for the progression of allograft vasculopathy and chronic rejection.Recent work has suggested that regulatory T cells may be an effective cellular therapy in transplantation. Given the above, adoptive therapy with CD4 regulatory T cells with indirect allospecificity is a rational first choice in attempting to attenuate the development and progression of chronic rejection; those with additional properties that enable inhibition of germinal center alloantibody responses hold particular appeal.

Graft rejection after hematopoietic cell transplantation with nonmyeloablative conditioning

DEFF Research Database (Denmark)

Masmas, T.N.; Petersen, S.L.; Madsen, H.O.

2008-01-01

over time. The storage temperature of the apheresis products was identified as a risk factor for rejection. Storage of the apheresis products at 5 degrees C diminished the risk of rejection. Low donor T cell chimerism at Day +14 significantly increased the risk of rejection. Seven patients were...

"Science" Rejects Postmodernism.

Science.gov (United States)

St. Pierre, Elizabeth Adams

2002-01-01

The National Research Council report, "Scientific Research in Education," claims to present an inclusive view of sciences in responding to federal attempts to legislate educational research. This article asserts that it narrowly defines science as positivism and methodology as quantitative, rejecting postmodernism and omitting other theories. Uses…

High-testosterone men reject low ultimatum game offers

OpenAIRE

Burnham, Terence C

2007-01-01

The ultimatum game is a simple negotiation with the interesting property that people frequently reject offers of ‘free’ money. These rejections contradict the standard view of economic rationality. This divergence between economic theory and human behaviour is important and has no broadly accepted cause. This study examines the relationship between ultimatum game rejections and testosterone. In a variety of species, testosterone is associated with male seeking dominance. If low ultimatum game...

UV Blocking Glass: Low Cost Filters for Visible Light Photocatalytic Assessment

Directory of Open Access Journals (Sweden)

Charles W. Dunnill

2014-01-01

Full Text Available A number of commercially available art protection products have been compared and assessed for their suitability as UV blocking filters in the application of “visible light” photocatalytic research. Many groups claiming visible light photocatalytic success employ filters to block out stray UV radiation in order to justify that their photocatalysts are indeed visible light photocatalysts and not UV light photocatalysts. These filters come in varying degrees of ability and price and many authors fail to correctly characterise their filters in individual papers. The use of effective filters to prevent both false positive and false negative results is important to maintain scientific rigor and create accurate understanding of the subject. The optimum UV filter would have the highest UV blocking properties (<390 nm and simultaneously the highest visible light transmission (390–750 nm. Single and double layers of each of the glass products were assessed as well as laminate products. The conclusions show an inexpensive and highly effective setup for the conduction of visible light photochemistry that should be incorporated as a standard part in any researcher’s work where the claim of visible light activity is made.

Radiation protection measurements with the variance-covariance method in the stray radiation fields from photon and proton therapy facilities

DEFF Research Database (Denmark)

Lillhök, J.; Persson, L.; Andersen, Claus E.

2017-01-01

, the dose-average lineal energy, the dose-average quality factor and the dose equivalent. The neutron component measured by the detectors at the proton beam was studied through Monte Carlo simulations using the code MCNP6. In the photon beam the stray absorbed dose ranged between 0.3 and 2.4 μGy per monitor...

The role of CD8+ T cells during allograft rejection

Directory of Open Access Journals (Sweden)

V. Bueno

2002-11-01

Full Text Available Organ transplantation can be considered as replacement therapy for patients with end-stage organ failure. The percent of one-year allograft survival has increased due, among other factors, to a better understanding of the rejection process and new immunosuppressive drugs. Immunosuppressive therapy used in transplantation prevents activation and proliferation of alloreactive T lymphocytes, although not fully preventing chronic rejection. Recognition by recipient T cells of alloantigens expressed by donor tissues initiates immune destruction of allogeneic transplants. However, there is controversy concerning the relative contribution of CD4+ and CD8+ T cells to allograft rejection. Some animal models indicate that there is an absolute requirement for CD4+ T cells in allogeneic rejection, whereas in others CD4-depleted mice reject certain types of allografts. Moreover, there is evidence that CD8+ T cells are more resistant to immunotherapy and tolerance induction protocols. An intense focal infiltration of mainly CD8+CTLA4+ T lymphocytes during kidney rejection has been described in patients. This suggests that CD8+ T cells could escape from immunosuppression and participate in the rejection process. Our group is primarily interested in the immune mechanisms involved in allograft rejection. Thus, we believe that a better understanding of the role of CD8+ T cells in allograft rejection could indicate new targets for immunotherapy in transplantation. Therefore, the objective of the present review was to focus on the role of the CD8+ T cell population in the rejection of allogeneic tissue.

A Choice Experiment Analysis of the Management of the Stray Dog Population in the UK.

OpenAIRE

Siettou, Christina; Fraser, Iain; Fraser, Rob

2013-01-01

In this paper we present the results of a pilot study investigating the public’s view on the pet overpopulation problem. The Choice Experiment aims to understand the UK public’s awareness of the issue, its views and its willingness to participate and pay for a reduction in the rate of animals being “put to sleep”. Our preliminary results indicate that the public are willing to pay to keep healthy stray dogs alive for longer in Local Authority kennels beyond the current seven day statutory per...

Development of enhanced sulfur rejection processes

Energy Technology Data Exchange (ETDEWEB)

Yoon, R.H.; Luttrell, G.H.; Adel, G.T.; Richardson, P.E.

1996-03-01

Research at Virginia Tech led to the development of two complementary concepts for improving the removal of inorganic sulfur from many eastern U.S. coals. These concepts are referred to as Electrochemically Enhanced Sulfur Rejection (EESR) and Polymer Enhanced Sulfur Rejection (PESR) processes. The EESR process uses electrochemical techniques to suppress the formation of hydrophobic oxidation products believed to be responsible for the floatability of coal pyrite. The PESR process uses polymeric reagents that react with pyrite and convert floatable middlings, i.e., composite particles composed of pyrite with coal inclusions, into hydrophilic particles. These new pyritic-sulfur rejection processes do not require significant modifications to existing coal preparation facilities, thereby enhancing their adoptability by the coal industry. It is believed that these processes can be used simultaneously to maximize the rejection of both well-liberated pyrite and composite coal-pyrite particles. The project was initiated on October 1, 1992 and all technical work has been completed. This report is based on the research carried out under Tasks 2-7 described in the project proposal. These tasks include Characterization, Electrochemical Studies, In Situ Monitoring of Reagent Adsorption on Pyrite, Bench Scale Testing of the EESR Process, Bench Scale Testing of the PESR Process, and Modeling and Simulation.

Some observations on stray magnetic fields and power outputs from short-wave diathermy equipment

Energy Technology Data Exchange (ETDEWEB)

Lau, R.W.M.; Dunscombe, P.B.

1984-04-01

Recent years have seen increasing interest in the possible hazards arising from the use of nonionizing electromagnetic radiation. Relatively large and potentially hazardous fields are to be found in the vicinity of short-wave and microwave equipment used in physiotherapy departments to produce therapeutic temperature rises. This note reports the results of measurements of the stray magnetic field and power output of a conventional short-wave diathermy unit when applied to tissue-equivalent phantoms. The dependence of these quantities on the variables, i.e. power setting of the unit, capacitor plate size, phantom size and phantom-capacitor plate separation, are discussed.

Total lymphoid irradiation for treatment of intractable cardiac allograft rejection

International Nuclear Information System (INIS)

Hunt, S.A.; Strober, S.; Hoppe, R.T.; Stinson, E.B.

1991-01-01

The ability of postoperative total lymphoid irradiation to reverse otherwise intractable cardiac allograft rejection was examined in a group of 10 patients in whom conventional rejection therapy (including pulsed steroids and monoclonal or polyclonal anti-T-cell antibody therapy) had failed to provide sustained freedom from rejection. Follow-up periods range from 73 to 1119 days since the start of total lymphoid irradiation. No patient died or sustained serious morbidity because of the irradiation. Three patients have had no further rejection (follow-up periods, 105 to 365 days). Two patients died--one in cardiogenic shock during the course of total lymphoid irradiation, the other with recurrent rejection caused by noncompliance with his medical regimen. Total lymphoid irradiation appears to be a safe and a moderately effective immunosuppressive modality for 'salvage' therapy of cardiac allograft rejection unresponsive to conventional therapy

Prevalence of Echinococcus granulosus taeniasis in stray dogs in the region of Constantine (North-East Algeria).

Science.gov (United States)

Kohil, K; Benchikh El Fegoun, M C; Gharbi, M

2017-10-01

In North Africa, the domestic dog is regarded as the main reservoir for infection by Echinococcus granulosus of domestic livestock and man. In Algeria, there is very little data on the rate of infestation of dogs, while the prevalence of E. granulosus in the definitive host is a very reliable marker of the potential risk of transmission of cystic tapeworm to humans and livestock. To find out this information, a survey was conducted to assess the prevalence of infection with E. granulosus in stray dogs in the region of Constantine (North-East Algeria). We autopsied and examined 120 stray dogs, 22 (18.3%) of which were infected with E. granulosus, with an average intensity of infestation of 249 worms. The prevalence in the area of survey was evaluated: 15.5% (14/90) and 26.6% (8/30) dogs were parasitized by E. granulosus in urban and rural areas respectively. The influence of age on the rate of infection was very marked. In addition, the appreciation of the prevalence of parasitism by cestodes as a whole showed that 56 (46.6%) animals out of 120 were infected. Facing such a situation of endemic tapeworm parasitism, with a potential risk of transmission to humans, there is an urgent need to take measures to control and break the epidemiological cycles of the parasite.

Local graft irradiation in renal transplant rejection

International Nuclear Information System (INIS)

Kawamura, Masashi; Kataoka, Masaaki; Itoh, Hisao

1990-01-01

From 1977 to 1988, of 142 renal transplantations, seven recipients (4.9%) received local graft irradiation following rejective reaction refractory to antirejection medical managements. Concurrent with the administration of pulsed high dose methylprednisolone and other antirejection medical managements, the graft was irradiated with a total dose of 6.0 Gy-150 cGy per fraction every other day at the midplane of the graft using two opposing portals of 4MX Linac. The fields were defined by palpation and echography. All patients had improvements in serum creatinine on the 10th day after beginning the irradiation. Four patients with peripheral lymphocytosis during the irradiation combined with pulsed high dose methylprednisolone improved in renal functions. On the other hand, out of 3 patients with lymphcytopenic changes, in two the transplanted graft was removed due to deteriorations, and the other patient is currently suffering from chronic rejection. Local graft irradiation can be useful in maintaining a rejective graft and reversing its functions in some patients whose rejective reaction failed to respond to the antirejection medical managements. (author)

Modeling rejection immunity

Directory of Open Access Journals (Sweden)

Gaetano Andrea De

2012-05-01

Full Text Available Abstract Background Transplantation is often the only way to treat a number of diseases leading to organ failure. To overcome rejection towards the transplanted organ (graft, immunosuppression therapies are used, which have considerable side-effects and expose patients to opportunistic infections. The development of a model to complement the physician’s experience in specifying therapeutic regimens is therefore desirable. The present work proposes an Ordinary Differential Equations model accounting for immune cell proliferation in response to the sudden entry of graft antigens, through different activation mechanisms. The model considers the effect of a single immunosuppressive medication (e.g. cyclosporine, subject to first-order linear kinetics and acting by modifying, in a saturable concentration-dependent fashion, the proliferation coefficient. The latter has been determined experimentally. All other model parameter values have been set so as to reproduce reported state variable time-courses, and to maintain consistency with one another and with the experimentally derived proliferation coefficient. Results The proposed model substantially simplifies the chain of events potentially leading to organ rejection. It is however able to simulate quantitatively the time course of graft-related antigen and competent immunoreactive cell populations, showing the long-term alternative outcomes of rejection, tolerance or tolerance at a reduced functional tissue mass. In particular, the model shows that it may be difficult to attain tolerance at full tissue mass with acceptably low doses of a single immunosuppressant, in accord with clinical experience. Conclusions The introduced model is mathematically consistent with known physiology and can reproduce variations in immune status and allograft survival after transplantation. The model can be adapted to represent different therapeutic schemes and may offer useful indications for the optimization of

Eosinophil count, allergies, and rejection in pediatric heart transplant recipients.

Science.gov (United States)

Arbon, Kate S; Albers, Erin; Kemna, Mariska; Law, Sabrina; Law, Yuk

2015-08-01

Allograft rejection and long-term immunosuppression remain significant challenges in pediatric heart transplantation. Pediatric recipients are known to have fewer rejection episodes and to develop more allergic conditions than adults. A T-helper 2 cell dominant phenotype, manifested clinically by allergies and an elevated eosinophil count, may be associated with immunologic quiescence in transplant recipients. This study assessed whether the longitudinal eosinophil count and an allergic phenotype were associated with freedom from rejection. This single-center, longitudinal, observational study included 86 heart transplant patients monitored from 1994 to 2011. Post-transplant biannual complete blood counts, allergic conditions, and clinical characteristics related to rejection risk were examined. At least 1 episode of acute cellular rejection (ACR) occurred in 38 patients (44%), antibody-mediated rejection (AMR) occurred in 11 (13%), and 49 patients (57%) were diagnosed with an allergic condition. Patients with ACR or AMR had a lower eosinophil count compared with non-rejectors (p = 0.011 and p = 0.022, respectively). In the multivariable regression analysis, the presence of panel reactive antibodies to human leukocyte antigen I (p = 0.014) and the median eosinophil count (p = 0.011) were the only independent covariates associated with AMR. Eosinophil count (p = 0.010) and female sex (p = 0.009) were independent risk factors for ACR. Allergic conditions or young age at transplant were not protective from rejection. This study demonstrates a novel association between a high eosinophil count and freedom from rejection. Identifying a biomarker for low rejection risk may allow a reduction in immunosuppression. Further investigation into the role of the T-helper 2 cell phenotype and eosinophils in rejection quiescence is warranted. Copyright © 2015 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Rejection of micropollutants by clean and fouled forward osmosis membrane

KAUST Repository

Valladares Linares, Rodrigo

2011-12-01

As forward osmosis (FO) gains attention as an efficient technology to improve wastewater reclamation processes, it is fundamental to determine the influence of fouling in the rejection of emerging contaminants (micropollutants). This study focuses on the rejection of 13 selected micropollutants, spiked in a secondary wastewater effluent, by a FO membrane, using Red Sea water as draw solution (DS), differentiating the effects on the rejection caused by a clean and fouled membrane. The resulting effluent was then desalinated at low pressure with a reverse osmosis (RO) membrane, to produce a high quality permeate and determine the rejection with a coupled forward osmosis - low pressure reverse osmosis (FO-LPRO) system. When considering only FO with a clean membrane, the rejection of the hydrophilic neutral compounds was between 48.6% and 84.7%, for the hydrophobic neutrals the rejection ranged from 40.0% to 87.5%, and for the ionic compounds the rejections were between 92.9% and 96.5%. With a fouled membrane, the rejections were between 44.6% and 95.2%, 48.7%-91.5% and 96.9%-98.6%, respectively. These results suggest that, except for the hydrophilic neutral compounds, the rejection of the micropollutants is increased by the presence of a fouling layer, possibly due to the higher hydrophilicity of the FO fouled membrane compared to the clean one, the increased adsorption capacity of hydrophilic compounds and reduced mass transport capacity, membrane swelling, and the higher negative charge of the membrane surface, related to the foulants composition, mainly NOM acids (carboxylic radicals) and polysaccharides or polysaccharide-like substances. However, when coupled with RO, the rejections in both cases increased above 96%. The coupled FO-LPRO system was an effective double barrier against the selected micropollutants. © 2011 Elsevier Ltd.

Rejection of micropollutants by clean and fouled forward osmosis membrane

KAUST Repository

Valladares Linares, Rodrigo; Yangali-Quintanilla, Victor; Li, Zhenyu; Amy, Gary L.

2011-01-01

As forward osmosis (FO) gains attention as an efficient technology to improve wastewater reclamation processes, it is fundamental to determine the influence of fouling in the rejection of emerging contaminants (micropollutants). This study focuses on the rejection of 13 selected micropollutants, spiked in a secondary wastewater effluent, by a FO membrane, using Red Sea water as draw solution (DS), differentiating the effects on the rejection caused by a clean and fouled membrane. The resulting effluent was then desalinated at low pressure with a reverse osmosis (RO) membrane, to produce a high quality permeate and determine the rejection with a coupled forward osmosis - low pressure reverse osmosis (FO-LPRO) system. When considering only FO with a clean membrane, the rejection of the hydrophilic neutral compounds was between 48.6% and 84.7%, for the hydrophobic neutrals the rejection ranged from 40.0% to 87.5%, and for the ionic compounds the rejections were between 92.9% and 96.5%. With a fouled membrane, the rejections were between 44.6% and 95.2%, 48.7%-91.5% and 96.9%-98.6%, respectively. These results suggest that, except for the hydrophilic neutral compounds, the rejection of the micropollutants is increased by the presence of a fouling layer, possibly due to the higher hydrophilicity of the FO fouled membrane compared to the clean one, the increased adsorption capacity of hydrophilic compounds and reduced mass transport capacity, membrane swelling, and the higher negative charge of the membrane surface, related to the foulants composition, mainly NOM acids (carboxylic radicals) and polysaccharides or polysaccharide-like substances. However, when coupled with RO, the rejections in both cases increased above 96%. The coupled FO-LPRO system was an effective double barrier against the selected micropollutants. © 2011 Elsevier Ltd.

Complement and hyper acute rejection

Directory of Open Access Journals (Sweden)

Al-Rabia Mohammed

2009-01-01

Full Text Available Organ transplantation has been a major development in clinical medicine but its success has been marred by the immune system′s capacity to respond to "non-self" cells and tissues. A full molecular understanding of this mechanism and the myriad triggers for immune rejection is yet to be elucidated. Consequently, immunosuppressive drugs remain the mainstay of post-transplant ma-nagement; however, these interventions have side effects such as increased incidence of cancer, post-transplant lymphoproliferative disorders, susceptibility to infection if not managed appro-priately and the inconvenience to the patient of lifelong treatment. Novel therapeutic approaches based on molecular understanding of immunological processes are thus needed in this field. The notion that factors influencing successful transplants might be of use as therapeutic approaches is both scientifically and medically appealing. Recent developments in the understanding of successful transplants are expected to provide new opportunities for safer transplantation. This article reviews the present understanding of the molecular basis of rejection and the role of complement in this process as well as the possibility of generating "intelligent" therapy that better target crucial components of hyper-acute rejections.

Antimyosin imaging in cardiac transplant rejection

International Nuclear Information System (INIS)

Johnson, L.L.; Cannon, P.J.

1991-01-01

Fab fragments of antibodies specific for cardiac myosin have been labeled with indium-111 and injected intravenously into animals and into patients with heart transplants. The antibodies, developed by Khaw, Haber, and co-workers, localize in cardiac myocytes that have been damaged irreversibly by ischemia, myocarditis, or the rejection process. After clearance of the labeled antibody from the cardiac blood pool, planar imaging or single photon emission computed tomography is performed. Scintigrams reveal the uptake of the labeled antimyosin in areas of myocardium undergoing transplant rejection. In animal studies, the degree of antimyosin uptake appears to correlate significantly with the degree of rejection assessed at necropsy. In patients, the correlation between scans and pathologic findings from endomyocardial biopsy is not as good, possibly because of sampling error in the endomyocardial biopsy technique. The scan results at 1 year correlate with either late complications (positive) or benign course (negative). Current limitations of the method include slow blood clearance, long half-life of indium-111, and hepatic uptake. Overcoming these limitations represents a direction for current research. It is possible that from these efforts a noninvasive approach to the diagnosis and evaluation of cardiac transplantation may evolve that will decrease the number of endomyocardial biopsies required to evaluate rejection. This would be particularly useful in infants and children. 31 references

Stray dogs and cats as potential sources of soil contamination with zoonotic parasites.

Science.gov (United States)

Szwabe, Katarzyna; Blaszkowska, Joanna

2017-03-22

The main source of many zoonoses is soil contaminated with feline and canine faeces. Thus, the aim of this study was to estimate the prevalence of intestinal parasites in stray dogs and cats adopted in Lodz shelter (Poland). In total, 163 faecal samples were collected from 95 dogs and 68 cats from 2011 to 2012. The samples were processed by sedimentation techniques using Mini Parasep®SF. Six parasite genera belonging to protozoa, cestoda, and nematoda, were found in dogs, while eight were found in cats. Out of the 163 fecal samples, 37.4% were positive for the presence at least one species of intestinal parasites. The majority of positive dog samples contained eggs from Toxocara and Trichuris genera, and the family Ancylostomatidae, while Toxocara and Taenia eggs, as well as Cystoisospora oocysts, predominated in cat faeces. A significantly higher prevalence of parasites was noted in cats (48.5%) than in dogs (29.5%) (χ2=6.15, P=0.013). The Toxocara genus was the most prevalent parasite in both populations; eggs were found in 27.9% and 16.8% of cats and dogs, respectively. Animals younger than 12 months of age showed higher infection rates with Toxocara, but differences were not statistically significant. The average numbers of Toxocara eggs/gram of faeces in positive puppy and kitten samples were over 5 and 7 times higher than in older dogs and cats, respectively. Mixed infection were found in dogs (5.3%) and cats (8.8%). Cat faeces represent a more important potential source of environmental contamination with zoonotic parasites than dog faeces. Among the detected parasites of stray dogs and cats, Toxocara present an important zoonotic risk for the local human population, especially children.

Structural Decoupling and Disturbance Rejection in a Distillation Column

DEFF Research Database (Denmark)

Bahar, Mehrdad; Jantzen, Jan; Commault, C.

1996-01-01

Introduction, distillation column model, input-output decoupling, disturbance rejection, concluding remarks, references.......Introduction, distillation column model, input-output decoupling, disturbance rejection, concluding remarks, references....

Rejection of crosstalk and noise by a quasi balanced CFPI for remote ultrasound detection

Energy Technology Data Exchange (ETDEWEB)

Reitinger, B; Berer, T; Hornhuber, C; Burgholzer, P, E-mail: bernhard.reitinger@recendt.at [Research Center for Non Destructive Testing GmbH (Recendt), Hafenstrasse 47-51, 4020 Linz (Austria)

2011-01-01

In this paper we show the benefits of a quasi balanced fringe hopping CFPI (confocal Fabry-Perot interferometer) with broadband CMRR (common mode rejection ratio) for remote ultrasound detection. Ultrasonic information in general lies in the phase modulation of laser light which in this case is demodulated by using the CFPI at a certain working point on a fringe. By hopping from the positive to the negative slope on the same fringe the detected ultrasonic signals are inverted. In contrary interference signals like crosstalk from the generation, ghosts, or noise correlated to pulse laser excitation are not influenced and hence get rejected by subtracting the signals from both slopes. Hence, a minimum of two measurements is needed for common mode rejection. The fringe hopping from the positive to the negative slope is done by changing the distance of the CFPI mirrors with a precise piezoelectric-stack and a fast high resolution digital controller. As only one photo-detector with a transimpedance-amplifier is needed a high CMRR can be accomplished which is not affected by the symmetry of the fringe but only by pulse to pulse energy fluctuations of the generation laser. We show that with fringe hopping and averaging the signal to noise ratio increases much faster than with averaging without fringe hopping. This is due to the correlation of the quasi-noise with the generation cycle.

THE DIAGNOSIS OF LIVER ALLOGRAFT ACUTE REJECTION IN LIVER BIOPSIES

Directory of Open Access Journals (Sweden)

L. V. Shkalova

2011-01-01

Full Text Available We performed histological examination of 80 liver allograft biopsies, the diagnosis of acute rejection was proved in 34 cases. Histological changes in liver biopsies in different grades of acute rejection were estimated according to Banff classification 1995, 1997 and were compared with current literature data. The article deals with the question of morphological value of grading acute rejection on early and late, also we analyze changes in treat- ment tactics after morphological verification of liver allograft acute rejection. 

Excluded from social security: rejections of disability pension applications in Norway 1998-2004.

Science.gov (United States)

Galaasen, Anders Mølster; Bruusgaard, Dag; Claussen, Bjørgulf

2012-03-01

Admission to disability pension (DP) in Norway, like most other countries, requires a medical condition as the main cause of income reduction. Still, a widespread assumption is that much of the recruitment to the programme is rather due to non-medical, mainly labour market factors. In this article, we study the grey zones between acceptance and rejection of DP applications, in light of the concept of marginalisation. From the total Norwegian population, aged 18-66 in 1998, we included all first-time applications for DP between 1998 and 2004. Logistic regressions of both application and application outcome were then performed, controlling for a range of socioeconomic variables and medical diagnosis. Medical diagnosis had the strongest impact on application outcome, together with the applicant's age. High rejection risk was found among applicants with complex musculoskeletal diagnoses, and also for complex psychiatric diagnoses as compared to well-defined ones. Persons having previously received social assistance more often applied for a DP and more often were rejected. The same is true, though on a lesser scale, for people with a weak affiliation to the labour market. The DP programme in Norway is to a large degree medically oriented, not only judicially but also in practice. Nevertheless, non-medical factors have a bearing on both application rates and application outcome. The control system seems to work in a way that excludes the most marginalised applicants, thus possibly contributing to further marginalisation of already disadvantaged groups.

Countering the stray magnetic field of the CUSP trap by using additional coils

CERN Document Server

Thole, Jelle

2016-01-01

The ASACUSA experiment at the Antiproton Decelerator (AD) at CERN tries to measure the Hyperfine Structure (HFS) of Antihydrogen (H ̄) using a Rabi spectroscopy set-up. In measuring this HFS it will yield a very precise test of CPT-symmetry. For this set-up to work a homogeneous magnetic field is needed in the cavity where the Hyperfine transition of H ̄ occurs. Due to the stray fields from the CUSP trap, where H ̄ is produced, additional coils are needed to counter these fields. It is found, using COMSOL simulations, that two coils are suitable for this. Leading to a relative standard deviation of the magnetic field of σB/B = 1.06%.

Non-clairvoyant weighted flow time scheduling with rejection penalty

DEFF Research Database (Denmark)

Chan, Ho-Leung; Chan, Sze-Hang; Lam, Tak-Wah

2012-01-01

is defined as the weighted flow time of the job plus the penalty if it is rejected before completion. Previous work on minimizing the total user cost focused on the clairvoyant single-processor setting [BBC+03,CLL11] and has produced O(1)-competitive online algorithm for jobs with arbitrary weights...... algorithm has to decide job rejection and determine the order and speed of job execution. It is interesting to study the tradeoff between the above-mentioned user cost and energy. This paper gives two O(1)-competitive non-clairvoyant algorithms for minimizing the user cost plus energy on a single processor......This paper initiates the study of online scheduling with rejection penalty in the non-clairvoyant setting, i.e., the size (processing time) of a job is not assumed to be known at its release time. In the rejection penalty model, jobs can be rejected with a penalty, and the user cost of a job...

Rechazo y retrasplante corneal Corneal rejection and re-transplantation

Directory of Open Access Journals (Sweden)

Miguel O Mokey Castellanos

2007-06-01

Full Text Available Se efectuó una investigación observacional análítica retrospectiva, sobre los transplantes corneales efectuados en el Servicio de Oftalmología del Hospital "Hermanos Ameijeiras. Rechazaron 76 pacientes, que se compararon con un control de 89 pacientes, que en un período similar no tuvieron rechazo. El queratocono fue la afección corneal que predominó. El primer lugar en los rechazos correspondió a queratoherpes (43,5 %. El menor índice de rechazo fue para el queratocono (8,8 %. Se analizó la multiplicidad de rechazos; y fue frecuente que se presentara un solo rechazo, aunque sí hubo congruencia entre el número de rechazos y la necesidad de retrasplantes. Se encontró que los resultados de la conducta médica o quirúrgica se relacionaban con la causa. Se calcula un índice de supervivencia (Kaplan-Meier, que concluye que en los primeros dos años existe menos posibilidad de aparición de rechazoAn retrospective observational analytical research was conducted on corneal transplants performed at Ophthalmological Service in “Hermanos Ameijeiras” hospital . Seventy six patients had graft rejection and were compared to a control group of 89 patients that did not present rejection in the same period of time. Keratoconus was the prevailing corneal problem. The highest rejection rate corresponded to keratoherpes (43,5% whereas the lowest rate was for keratoconus (8,8%. Multiplicity of rejections was analyzed and it was found that mostly one graft rejection occured, but number of rejections was associated with the need of re-transplantation. It was found that the results of medical or surgical performance were related to the cause of graft rejection. A survival index (Kaplan-Meier was estimated, which showed that occurence of graf rejection is less probable in the first two years

Apoptosis of acinar cells in pancreas allograft rejection

NARCIS (Netherlands)

Boonstra, J. G.; Wever, P. C.; Laterveer, J. C.; Bruijn, J. A.; van der Woude, F. J.; ten Berge, I. J.; Daha, M. R.

1997-01-01

BACKGROUND: Recently it has been recognized that apoptosis of target cells may occur during liver and kidney allograft rejection and is probably induced by infiltrating cells. Pancreas rejection is also characterized by a cellular infiltrate, however, the occurrence of apoptosis has not been

Mammographic image reject rate analysis and cause – A National Maltese Study

International Nuclear Information System (INIS)

Mercieca, N.; Portelli, J.L.; Jadva-Patel, H.

2017-01-01

Mammography is used as a first-line investigation in the detection of breast cancer and imaging is required to be of optimal quality and achieved without adverse effects on the health of individuals. Repeated images come at a cost in terms of radiation dose, discomfort to clients and unnecessary financial burdens. No studies investigating mammography quality in Malta had been previously undertaken. Hence, this research aimed to investigate whether mammography is being performed at an acceptable level, through the investigation of reject rates. Quantitative methodology was used to collect data from eight participating mammography units, which were utilising screen film (SFM), computed radiography (CR) and direct digital mammography (DDM). Data relating to the total number of images performed, rejects and causes was prospectively collected over two weeks, resulting in a sample of 2291 images. All units were also asked to answer a questionnaire which provided other data that could be used for analysis. The national mammography reject rate was found to be 2.62%; within the 3% acceptable range. Individual rates' analysis revealed unacceptably high or low reject rates in some units. Positioning was the main reject cause. No significant difference in rejection was found between different types of mammography units or radiographers' experience. Alternatively, radiographers' qualifications, employment conditions and use of rejection criteria were proven to affect reject rates. Whilst on a national level, images are being rejected at an acceptable rate, individual units revealed suboptimal rates; at the cost of extra radiation, added discomfort and financial burden. - Highlights: • The national reject rate complied with the European Guidelines. • Reject rates in different units were found to vary. • Positioning was the commonest cause for repeats. • The equipment used and radiographers' experience did not affect reject rates. • Qualifications

Prevalence and Potential Risk Factors for Bartonella Infection in Tunisian Stray Dogs.

Science.gov (United States)

Belkhiria, Jaber; Chomel, Bruno B; Ben Hamida, Taoufik; Kasten, Rickie W; Stuckey, Matthew J; Fleischman, Drew A; Christopher, Mary M; Boulouis, Henri-Jean; Farver, Thomas B

2017-06-01

Bartonellae are blood-borne and vector-transmitted pathogens, some are zoonotic, which have been reported in several Mediterranean countries. Transmission from dogs to humans is suspected, but has not been clearly demonstrated. Our objectives were to determine the seroprevalence of Bartonella henselae, Bartonella vinsonii subsp. berkhoffii, Bartonella clarridgeiae, and Bartonella bovis (as a proxy for Candidatus Bartonella merieuxii) in stray dogs from Tunisia, identify the Bartonella species infecting the dogs and evaluate potential risk factors for canine infection. Blood samples were collected between January and November 2013 from 149 dogs in 10 Tunisian governorates covering several climatic zones. Dog-specific and geographic variables were analyzed as potential risk factors for Bartonella spp. seropositivity and PCR-positivity. DNA was extracted from the blood of all dogs and tested by PCR for Bartonella, targeting the ftsZ and rpoB genes. Partial sequencing was performed on PCR-positive dogs. Twenty-nine dogs (19.5%, 95% confidence interval: 14-27.4) were seropositive for one or more Bartonella species, including 17 (11.4%) for B. vinsonii subsp. berkhoffii, 14 (9.4%) for B. henselae, 13 (8.4%) for B. clarridgeiae, and 7 (4.7%) for B. bovis. Statistical analysis revealed a few potential risk factors, mainly dog's age and breed, latitude and average winter temperature. Twenty-two (14.8%) dogs, including 8 of the 29 seropositive dogs, were PCR-positive for Bartonella based on the ftsZ gene, with 18 (81.8%) of these 22 dogs also positive for the rpoB gene. Partial sequencing showed that all PCR-positive dogs were infected with Candidatus B. merieuxii. Dogs from arid regions and regions with cold average winter temperatures were less likely to be PCR-positive than dogs from other climatic zones. The widespread presence of Bartonella spp. infection in Tunisian dogs suggests a role for stray dogs as potential reservoirs of Bartonella species in Tunisia.

Rejection or selection: influence of framing in investment decisions.

Science.gov (United States)

Cheng, Pi-Yueh; Chiou, Wen-Bin

2010-02-01

According to prospect theory, reflection effects result in preferences for risk-averse choices in gain situations and risk-seeking choices in loss situations. However, relevant literature in regard to decision making has suggested that positive information receives more weight in a selection task, whereas negative information receives more weight in a rejection task. The present study examined whether the nature of a decision task (selection vs rejection) would moderate the reflection effects. Undergraduates (47 men, 49 women; M age = 20.5 yr., SD = 1.1), selected according to specific screening criteria, participated in an experimental study. Typical reflection effects were observed in both selection and rejection task conditions. More importantly, negative information (i.e., the information about probable loss in risky choice of gain situations and the information about certain loss in cautious choice of loss situations) provided in the context of a rejection task received more weight and resulted in more frequent endorsements of the cautious choice in gain situations and of the risky choice in loss situations. Hence, the findings suggest that a decision context characterized by rejection may expand the reflection effects and thereby provide important information about situations in which investment decisions occur in a context characterized by rejection.

Indium-labeled platelet uptake in rejecting renal transplants

International Nuclear Information System (INIS)

Chandler, S.T.; Buckels, J.; Hawker, R.J.; Smith, N.; Barnes, A.D.; McCollum, C.N.

1983-01-01

The uptake of 111 In autologous platelets in transplanted kidneys was measured in 16 patients shortly after operation. Each patient was then observed for two years. When transplant radioactivity had increased, despite treatment for acute rejection, the kidney was ultimately lost because of rejection

Perceived childhood paternal acceptance-rejection among adults

International Nuclear Information System (INIS)

Hussain, S.; Alvi, T.; Zeeshan, A.; Nadeem, S.

2013-01-01

Objective: To determine the childhood perceptual difference of paternal acceptance-rejection between those having psychological disorders and non-clinical population during adulthood. Study Design: Comparative study. Place and Duration of Study: Karwan-e-Hayat, Psychiatric Care and Rehabilitation Centre, Keamari, Karachi, Pakistan, from January to August 2011. Methodology: To test our hypotheses, 69 participants were selected from Karwan-e-Hayat Psychiatric Care and Rehabilitation Centre, Karachi on the basis of purposive sampling technique and 79 from Karachi city on the basis of convenient sampling technique. To measure their perceived paternal acceptance-rejection during childhood, Adult Parental acceptance-rejection questionnaire (PARQ)/control: father-short form (Urdu translation) was administered. The statistical analysis of data was done with the predictive analytics software (PASW). Results: One hundred and forty eight (78 males and 70 females) participants with mean age of 31.28 +- 9.54 years were included. Out of them 69 (40 males and 29 females) were clinical cases of depression, mania and psychosis with mean age of 33.26 +- 9.51 years. Seventy nine (38 males and 41 females) were normal individuals with mean age of 29.54 +- 9.29 years of the demographics corresponding to the clinical population. Independent t-test revealed a significant difference in perceived childhood father acceptance-rejection between clinical and non-clinical population (p < 0.05) and significant gender difference (p < 0.05). Conclusion: The studied clinical population and male participants perceived to be more rejected by their father during their childhood than non-clinical population and female participants. (author)

Rejection of Organic Micropollutants by Clean and Fouled Nanofiltration Membranes

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Lifang Zhu

2015-01-01

Full Text Available The rejection of organic micropollutants, including three polycyclic aromatic hydrocarbons (PAHs and three phthalic acid esters (PAEs, by clean and fouled nanofiltration membranes was investigated in the present study. The rejection of organic micropollutants by clean NF90 membranes varied from 87.9 to more than 99.9%, while that of NF270 membranes ranged from 32.1 to 92.3%. Clear time-dependence was observed for the rejection of hydrophobic micropollutants, which was attributed to the adsorption of micropollutants on the membrane. Fouling with humic acid had a negligible influence on the rejection of organic micropollutants by NF90 membranes, while considerable effects were observed with NF270 membranes, which are significantly looser than NF90 membranes. The observed enhancement in the rejection of organic micropollutants by fouled NF270 membranes was attributed to pore blocking, which was a dominating fouling mechanism for loose NF membranes. Changes in the ionic strength (from 10 to 20 mM reduced micropollutant rejection by both fouled NF membranes, especially for the rejection of dimethyl phthalate and diethyl phthalate by NF270 membranes (from 65.8 to 25.0% for dimethyl phthalate and 75.6 to 33.3% for diethyl phthalate.

Comparison of the Multi-anode PMTs with the old HF PMTs by Studying the Collision Data

CERN Document Server

Oz, Yavuz

2013-01-01

The Hadron Forward (HF) calorimeter of the CMS detector improves jet detection and missing transverse energy resolution in the high pseudorapidity range. HF employs photomultiplier tubes (PMT) that measure the Cerenkov light emitted by shower products in quartz fibers. Stray muons that hit a PMT window create high energy events that are difficult to reject. To alleviate this problem, the PMTs installed in the CMS will be replaced with those of better performance. From among various candidate PMTs, quad-anode Hamamatsu R7600U-200-M4 were chosen to replace the single-anode Hamamatsu R7525HA PMTs. The quad-anode PMTs offer the possibility to reject window events at the hardware level; muons hitting the window are localized to a single anode, while real events illuminate all four anodes. In 2011, eight such PMTs were installed in the readout boxes corresponding to the coordinates $i\\phi=67$, $i\\eta=29,30,31,32$, which get very few hits on account of their location. The purpose of this thesis is to compare the res...

Outside advantage: can social rejection fuel creative thought?

Science.gov (United States)

Kim, Sharon H; Vincent, Lynne C; Goncalo, Jack A

2013-08-01

Eminently creative people working in fields as disparate as physics and literature refer to the experience of social rejection as fuel for creativity. Yet, the evidence of this relationship is anecdotal, and the psychological process that might explain it is as yet unknown. We theorize that the experience of social rejection may indeed stimulate creativity but only for individuals with an independent self-concept. In 3 studies, we show that individuals who hold an independent self-concept performed more creatively after social rejection relative to inclusion. We also show that this boost in creativity is mediated by a differentiation mind-set, or salient feelings of being different from others. Future research might investigate how the self-concept--for example, various cultural orientations-may shape responses to social rejection by mitigating some of the negative consequences of exclusion and potentially even motivating creative exploration. PsycINFO Database Record (c) 2013 APA, all rights reserved.

Diagnosis of Rejection by Analyzing Ventricular Late Potentials in Heart Transplant Patients

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Vítor Nogueira Mendes

2016-01-01

Full Text Available Background: Heart transplant rejection originates slow and fragmented conduction. Signal-averaged ECG (SAECG is a stratification method in the risk of rejection. Objective: To develop a risk score for rejection, using SAECG variables. Methods: We studied 28 transplant patients. First, we divided the sample into two groups based on the occurrence of acute rejection (5 with rejection and 23 without. In a second phase, we divided the sample considering the existence or not of rejection in at least one biopsy performed on the follow-up period (rejection pm1: 18 with rejection and 10 without. Results: On conventional ECG, the presence of fibrosis was the only criterion associated with acute rejection (OR = 19; 95% CI = 1.65-218.47; p = 0.02. Considering the rejection pm1, an association was found with the SAECG variables, mainly with RMS40 (OR = 0.97; 95% CI = 0.87-0.99; p = 0.03 and LAS40 (OR = 1.06; 95% IC = 1.01-1.11; p = 0.03. We formulated a risk score including those variables, and evaluated its discriminative performance in our sample. The presence of fibrosis with increasing of LAS40 and decreasing of RMS40 showed a good ability to distinguish between patients with and without rejection (AUC = 0.82; p < 0.01, assuming a cutoff point of sensitivity = 83.3% and specificity = 60%. Conclusion: The SAECG distinguished between patients with and without rejection. The usefulness of the proposed risk score must be demonstrated in larger follow-up studies.

Fate of Manuscripts Rejected From the Red Journal

International Nuclear Information System (INIS)

Holliday, Emma B.; Yang, George; Jagsi, Reshma; Hoffman, Karen E.; Bennett, Katherine Egan; Grace, Calley; Zietman, Anthony L.

2015-01-01

Purpose: To evaluate characteristics associated with higher rates of acceptance for original manuscripts submitted for publication to the International Journal of Radiation Oncology • Biology • Physics (IJROBP) and describe the fate of rejected manuscripts. Methods and Materials: Manuscripts submitted to the IJROBP from May 1, 2010, to August 31, 2010, and May 1, 2012, to August 31, 2012, were evaluated for author demographics and acceptance status. A PubMed search was performed for each IJROBP-rejected manuscript to ascertain whether the manuscript was ultimately published elsewhere. The Impact Factor of the accepting journal and the number of citations of the published manuscript were also collected. Results: Of the 500 included manuscripts, 172 (34.4%) were accepted and 328 (65.6%) were rejected. There was no significant difference in acceptance rates according to gender or degree of the submitting author, but there were significant differences seen based on the submitting author's country, rank, and h-index. On multivariate analysis, earlier year submitted (P<.0001) and higher author h-index (P=.006) remained significantly associated with acceptance into the IJROBP. Two hundred thirty-five IJROBP-rejected manuscripts (71.7%) were ultimately published in a PubMed-listed journal as of July 2014. There were no significant differences in any submitting author characteristics. Journals accepting IJROBP-rejected manuscripts had a lower median [interquartile range] 2013 impact factor compared with the IJROBP (2.45 [1.53-3.71] vs 4.176). The IJROBP-rejected manuscripts ultimately published elsewhere had a lower median [interquartile range] number of citations (1 [0-4] vs 6 [2-11]; P<.001), which persisted on multivariate analysis. Conclusions: The acceptance rate for manuscripts submitted to the IJROBP is approximately one-third, and approximately 70% of rejected manuscripts are ultimately published in other PubMed-listed journals, but these ultimate

Action against Kruemmel rejected

International Nuclear Information System (INIS)

Anon.

1976-01-01

In its verdict dated September 2nd, 1976 - 10 A 211/74 -, the administrative court of Schleswig-Holstein at Schleswig has rejected with costs the action of a plaintiff resident in Hessen concerning the contestation of the 2nd partial licence for the erection of a nuclear power station at Kruemmel near Hamburg. The verdict is not subject to appeal. Furthermore, the administrative court of Schleswig-Holstein at Schleswig, in its verdict dated September 2nd, 1976 - 10 A 214/74 - has rejected with costs the actions of eight plaintiffs living in Hamburg and surroundings, concerning the contestation of the 1st, 2nd and 3rd partial licence for the erection of a nuclear power station at Kruemmel near Hamburg. An appeal against this verdict has been lodged at the higher administrative court at Lueneburg. The main gounds for the two judgments are given in full text. (orig./HP) [de

A report on the alimentary canal helminthic infestation of stray and pet dogs in Tabriz

Directory of Open Access Journals (Sweden)

Y Gharedaghi

2008-08-01

Full Text Available From September to December 2007, fecal specimens of 100 stray and pet dogs in Tabriz were examined by saturated salt flotation and Telmann sedimentation methods to determine the prevalence of gastrointestinal helminth infestation. Helminth infestation was encountered in 31 (31% of the fecal samples examined. The eggs of two different cestodes and three different nematodes were identified in the contaminated fecal samples. The helminth eggs found were identified as Taenia hydatigena (4%, Dipylidium caninum (6%, Toxocara canis (10%, Ancylostoma caninum (6% and Trichuris vulpis (5%. No trematoda eggs and nematode larvae were found in this study.

Scanning thin-sheet laser imaging microscopy (sTSLIM) with structured illumination and HiLo background rejection.

Science.gov (United States)

Schröter, Tobias J; Johnson, Shane B; John, Kerstin; Santi, Peter A

2012-01-01

We report replacement of one side of a static illumination, dual sided, thin-sheet laser imaging microscope (TSLIM) with an intensity modulated laser scanner in order to implement structured illumination (SI) and HiLo image demodulation techniques for background rejection. The new system is equipped with one static and one scanned light-sheet and is called a scanning thin-sheet laser imaging microscope (sTSLIM). It is an optimized version of a light-sheet fluorescent microscope that is designed to image large specimens (HiLo image demodulation. The static light-sheet has a thickness of 3.2 µm; whereas, the scanned side has a light-sheet thickness of 4.2 µm. The scanned side images specimens with subcellular resolution (HiLo produce superior contrast compared to both the uniform static and scanned light-sheets. HiLo contrast was greater than SI and is faster and more robust than SI because as it produces images in two-thirds of the time and exhibits fewer intensity streaking artifacts. 2011 Optical Society of America

The resistance of delayed xenograft rejection to alpha(1,3)-galactosyltransferase gene inactivation and CD4 depletion in a mouse-to-rat model

DEFF Research Database (Denmark)

Hansen, Alastair B; Kirkeby, Svend; Aasted, Bent

2003-01-01

furthermore CD4 depleted in order to inhibit CD4-dependent B-cell antibody production. Rejected hearts were evaluated by light- and immunofluorescence microscopy. Treatment effects on recipient T-cell subsets and cytokine expression were analyzed by flow cytometry, while antibody production was measured...

Multiquadrant Subtenon Triamcinolone Injection for Acute Corneal Graft Rejection: A Case Report

Directory of Open Access Journals (Sweden)

Sunali Goyal

2017-05-01

Full Text Available Background: We report a case of reversal of an acute corneal graft rejection following multiquadrant subtenon triamcinolone injection. Case Presentation: A 19-year-old woman who had acute corneal graft rejection failed to show resolution of the graft rejection after standard treatment with systemic, intravenous, and topical steroids. The graft rejection, however, responded to injection of triamcinolone in multiple subtenon quadrants. Conclusions: For corneal graft rejection, multiquadrant subtenon triamcinolone injections may be a safe adjunct to systemic treatment.

Measurement and application of bidirectional reflectance distribution function

Science.gov (United States)

Liao, Fei; Li, Lin; Lu, Chengwen

2016-10-01

When a beam of light with certain intensity and distribution reaches the surface of a material, the distribution of the diffused light is related to the incident angle, the receiving angle, the wavelength of the light and the types of the material. Bidirectional Reflectance Distribution Function (BRDF) is a method to describe this distribution. For an optical system, the optical and mechanical materials' BRDF are unique, and if we want to calculate stray light of the system we should know the correct BRDF data of the whole materials. There are fundamental significances in the area of space remote sensor where BRDF is needed in the precise radiation calibration. It is also important in the military field where BRDF can be used in the object identification and target tracking, etc. In this paper, 11 kinds of aerospace materials' BRDF are measured and more than 310,000 groups of BRDF data are achieved , and also a BRDF database is established in China for the first time. With the BRDF data of the database, we can create the detector model, build the stray light radiation surface model in the stray light analysis software. In this way, the stray radiation on the detector can be calculated correctly.

A protocol for arguing about rejections in negotiation

NARCIS (Netherlands)

Prakken, Henry; van Veenen, J.; Parsons, S; Maudet, N; Moraitis, P; Rahwan,

2006-01-01

One form of argument-based negotiation is when agents argue about why an offer was rejected. If an agent can state a reason for a rejection of an offer, the negotiation process may become more efficient since the other agent can take this reason into account when making new offers. Also, if a reason

Prosthesis rejection in acquired major upper-limb amputees: a population-based survey.

Science.gov (United States)

Østlie, Kristin; Lesjø, Ingrid Marie; Franklin, Rosemary Joy; Garfelt, Beate; Skjeldal, Ola Hunsbeth; Magnus, Per

2012-07-01

To estimate the rates of primary and secondary prosthesis rejection in acquired major upper-limb amputees (ULAs), to describe the most frequently reported reasons for rejection and to estimate the influence of background factors on the risk of rejection. Cross-sectional study analysing population-based questionnaire data (n = 224). Effects were analysed by logistic regression analyses and Cox regression analyses. Primary prosthesis rejection was found in 4.5% whereas 13.4% had discontinued prosthesis use. The main reasons reported for primary non-wear were a perceived lack of need and discrepancies between perceived need and the prostheses available. The main reasons reported for secondary prosthesis rejection were dissatisfaction with prosthetic comfort, function and control. Primary prosthesis rejection was more likely in ULAs amputated at high age and in ULAs with proximal amputations. Secondary prosthesis rejection was more likely in proximal ULAs and in women. Clinicians should be aware of the increased risk of rejection in proximal ULAs, elderly ULAs and in women. Emphasising individual needs will probably facilitate successful prosthetic fitting. Improved prosthesis quality and individualised prosthetic training may increase long-term prosthesis use. Further studies of the effect of prosthetic training and of the reasons for rejection of different prosthetic types are suggested.

Brain Region-Dependent Rejection of Neural Precursor Cell Transplants

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Nina Fainstein

2018-04-01

Full Text Available The concept of CNS as an immune-privileged site has been challenged by the occurrence of immune surveillance and allogeneic graft rejection in the brain. Here we examined whether the immune response to allogeneic neural grafts is determined by the site of implantation in the CNS. Dramatic regional differences were observed between immune responses to allogeneic neural precursor/stem cell (NPC grafts in the striatum vs. the hippocampus. Striatal grafts were heavily infiltrated with IBA-1+ microglia/macrophages and CD3+ T cells and completely rejected. In contrast, hippocampal grafts exhibited milder IBA-1+ cell infiltration, were not penetrated efficiently by CD3+ cells, and survived efficiently for at least 2 months. To evaluate whether the hippocampal protective effect is universal, astrocytes were then transplanted. Allogeneic astrocyte grafts elicited a vigorous rejection process from the hippocampus. CD200, a major immune-inhibitory signal, plays an important role in protecting grafts from rejection. Indeed, CD200 knock out NPC grafts were rejected more efficiently than wild type NPCs from the striatum. However, lack of CD200 expression did not elicit NPC graft rejection from the hippocampus. In conclusion, the hippocampus has partial immune-privilege properties that are restricted to NPCs and are CD200-independent. The unique hippocampal milieu may be protective for allogeneic NPC grafts, through host-graft interactions enabling sustained immune-regulatory properties of transplanted NPCs. These findings have implications for providing adequate immunosuppression in clinical translation of cell therapy.

Is the bitter rejection response always adaptive?

Science.gov (United States)

Glendinning, J I

1994-12-01

The bitter rejection response consists of a suite of withdrawal reflexes and negative affective responses. It is generally assumed to have evolved as a way to facilitate avoidance of foods that are poisonous because they usually taste bitter to humans. Using previously published studies, the present paper examines the relationship between bitterness and toxicity in mammals, and then assesses the ecological costs and benefits of the bitter rejection response in carnivorous, omnivorous, and herbivorous (grazing and browsing) mammals. If the bitter rejection response accurately predicts the potential toxicity of foods, then one would expect the threshold for the response to be lower for highly toxic compounds than for nontoxic compounds. The data revealed no such relationship. Bitter taste thresholds varied independently of toxicity thresholds, indicating that the bitter rejection response is just as likely to be elicited by a harmless bitter food as it is by a harmful one. Thus, it is not necessarily in an animal's best interest to have an extremely high or low bitter threshold. Based on this observation, it was hypothesized that the adaptiveness of the bitter rejection response depends upon the relative occurrence of bitter and potentially toxic compounds in an animal's diet. Animals with a relatively high occurrence of bitter and potentially toxic compounds in their diet (e.g., browsing herbivores) were predicted to have evolved a high bitter taste threshold and tolerance to dietary poisons. Such an adaptation would be necessary because a browser cannot "afford" to reject all foods that are bitter and potentially toxic without unduly restricting its dietary options. At the other extreme, animals that rarely encounter bitter and potentially toxic compounds in their diet (e.g., carnivores) were predicted to have evolved a low bitter threshold. Carnivores could "afford" to utilize such a stringent rejection mechanism because foods containing bitter and potentially

The arcuate artery in renal transplants: An insensitive indicator of rejection

International Nuclear Information System (INIS)

McIntire, J.N.; Angtuaco, T.L.; Boyd, C.; Flanigan, W.J.

1987-01-01

The authors performed 65 duplex US examinations in 28 patients within 2 years of transplantation. During this time 15 episodes of rejection were diagnosed by US and confirmed clinically. Of the remaining 50 examinations, 14 showed negligible or absent diastolic flow (suggesting rejection) in the arcuate arteries with normal diastolic flow in the main renal, segmental, and interlobar branches. No other criteria for rejection were present in these patients. It is concluded that the arcuate artery is an insensitive indicator of transplant rejection

Design and testing of a magnetic shield for the Thomson scattering photomultiplier tubes in the stray fields of the ERASMUS tokamak

International Nuclear Information System (INIS)

Desoppere, E.; Van Oost, G.

1983-01-01

A multiple coaxial shield system has been designed for the photomultiplier tubes of the ERASMUS tokamak Thomson scattering diagnostic. A stray field of 75 x 10 -4 T was reduced to 0.01 x 10 -4 T for a field parallel to the tube axis, and to 0.03 x 10 -4 T for a perpendicular field

Rejection as a call to arms: inter-racial hostility and support for political action as outcomes of race-based rejection in majority and minority groups.

Science.gov (United States)

Barlow, Fiona Kate; Sibley, Chris G; Hornsey, Matthew J

2012-03-01

Both majority and minority group members fear race-based rejection, and respond by disparaging the groups that they expect will reject them. It is not clear, however, how this process differs in minority and majority groups. Using large representative samples of White (N= 4,618) and Māori (N= 1,163) New Zealanders, we found that perceptions of race-based rejection predicted outgroup negativity in both groups, but in different ways and for different reasons. For White (but not Māori) New Zealanders, increased intergroup anxiety partially mediated the relationship between cognitions of rejection and outgroup negativity. Māori who expected to be rejected on the basis of their race reported increased ethnic identification and, in part through this, increased support for political action benefiting their own group. This finding supports collective-action models of social change in historically disadvantaged minority groups. © 2011 The British Psychological Society.

Preventing Allograft Rejection by Targeting Immune Metabolism

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Chen-Fang Lee

2015-10-01

Full Text Available Upon antigen recognition and co-stimulation, T lymphocytes upregulate the metabolic machinery necessary to proliferate and sustain effector function. This metabolic reprogramming in T cells regulates T cell activation and differentiation but is not just a consequence of antigen recognition. Although such metabolic reprogramming promotes the differentiation and function of T effector cells, the differentiation of regulatory T cells employs different metabolic reprogramming. Therefore, we hypothesized that inhibition of glycolysis and glutamine metabolism might prevent graft rejection by inhibiting effector generation and function and promoting regulatory T cell generation. We devised an anti-rejection regimen involving the glycolytic inhibitor 2-deoxyglucose (2-DG, the anti-type II diabetes drug metformin, and the inhibitor of glutamine metabolism 6-diazo-5-oxo-L-norleucine (DON. Using this triple-drug regimen, we were able to prevent or delay graft rejection in fully mismatched skin and heart allograft transplantation models.

Stray current induced corrosion in lightning rod cables of 525 kV power lines towers: a case study

OpenAIRE

Wojcicki, F. R.; Negrisoli, M. E. M.; Franco, C. V.

2003-01-01

With the growth of several areas in modem society, the necessity to generate and carry electrical energy to big cities has greatly increased. Cables supported by power towers with galvanized steel foundation usually carry energy. As the foundations are underground they may cause high rates of corrosion. These are usually detected by a conventional potential measurement using a Cu/CuSO₄ reference electrode. It is believed that corrosion results from stray currents that f...

Phenomenology’s Rejects: Religion after Derrida’s Denegations

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Alvis Jason W.

2017-10-01

Full Text Available Religion, as well as any individuals’ volitionally chosen ‟worldview,” generally get conceived solely in affirmative terms of value. ‟Religion” has been conceptualized almost solely on the terms of axiology: as the experience of ‟the greatest” holiness (Otto, the purely valuable sacred (Eliade; the most ‟ultimate concern” (Tillich; the symbols accepted to order life (Geertz, or the binding of oneself to deep value (Müller. Yet there are limitations of such axiomatic thinking, limitations that can be exemplified through an interpretation of Derrida’s ‟globolatinization,” which he described as a system of thought that promotes a universalism of pseudo or petit-valuations, and punishes those resistant and inflexible to them in the name of toleration. This essay investigates what happens when this ‟axiomatic” register (i.e. a reduction to a set of values gets displaced in order to conceptualize religion also in terms of the nonvaluable or ‟rejected.” Rejection entails the paradox that what is rejected often speaks to a deeper reality of what in fact is desired. Thus, what we reject usually says infinitely more about us than what we claim to value and affirm. This essay interprets Derrida’s essay ‟How to Avoid Speaking: Denials” alongside his ‟Faith and Knowledge” in order to offer a Derridean conception of religion on the terms of a rejection that amounts to a double-affirmation or de-negation.

Friendship quantity and quality as predictors of rejection sensitivity in adolescents

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Gabriela Šeboková

2014-12-01

Full Text Available The current study examines friendship quality and quantity as unique predictors of rejection sensitivity in adolescents. The purpose of the study was to analyze whether the unique contributions of friendship quality and quantity differ in adolescent boys and girls. Rejection sensitivity is conceptualized as the disposition to anxiously expect, readily perceive and intensively react to social rejection. That is why rejection sensitivity is considered to be a cognitive-affective mechanism which leads to increase of internalizing problems in children and adolescents (loneliness, social anxiety, depression.... Friendship variables have been found to predict the level of internalizing problems in adolescents. Little to no research, however, has examined friendship quality and quantity as predictors of level of rejection sensitivity. Participants in this study were 184 students (98 girls and 86 boys, aged from 13 to 16 (M=13.83, SD=1. Adolescents completed measures assessing number of their friends, quality of best friendship (self-report questionnaire Friendship qualities scale, Bukowski, Hoza, Boivin, 1994 and rejection sensitivity (self-report questionnaire Rejection sensitivity scale, Downey, Feldman, 1996. Regression analysis indicated that friendship features (companionship, balance, help, security, closeness, friendship quantity and overall friendship quality are significant unique predictors of sensitivity rejection in adolescents with. Results suggest that adolescents with higher number of and higher quality friendships have lower concerns about the possibility and expectation of rejection, which can lead to minimizing the risk of development of internalizing problems. However, only a small proportion of variance was accounted for in rejection sensitivity by the friendship variables (small to medium effect size. This suggests that different kind of peer relationships (peer acceptance, popularity, peer victimization make unique, differential

Explaining the paradoxical rejection-aggression link: the mediating effects of hostile intent attributions, anger, and decreases in state self-esteem on peer rejection-induced aggression in youth.

Science.gov (United States)

Reijntjes, Albert; Thomaes, Sander; Kamphuis, Jan H; Bushman, Brad J; de Castro, Bram Orobio; Telch, Michael J

2011-07-01

People are strongly motivated to feel accepted by others. Yet when faced with acute peer rejection they often aggress against the very peers they desire acceptance from, which may lead to further rejection. The present experiment tests three potential mediators of aggressive responses to acute peer rejection in the critical developmental stage of early adolescence. Participants (N=185, M(age)=11.5 years) completed personal profiles that were allegedly evaluated online by peers. After receiving negative or neutral peer feedback, participants could aggress against the same peers who had evaluated them. Rejected participants attributed more hostile intent to the peers, were angrier, showed a greater reduction in state self-esteem, and were more aggressive. Mediational analyses showed that hostile intent attributions mediated the acute peer rejection-aggression relationship, whereas increases in anger and decreases in state self-esteem did not. Thus, acute peer rejection evokes hostile intent attributions that, in turn, lead to aggressive reactions. © 2011 by the Society for Personality and Social Psychology, Inc

Insights from computational modeling in inflammation and acute rejection in limb transplantation.

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Dolores Wolfram

Full Text Available Acute skin rejection in vascularized composite allotransplantation (VCA is the major obstacle for wider adoption in clinical practice. This study utilized computational modeling to identify biomarkers for diagnosis and targets for treatment of skin rejection. Protein levels of 14 inflammatory mediators in skin and muscle biopsies from syngeneic grafts [n = 10], allogeneic transplants without immunosuppression [n = 10] and allografts treated with tacrolimus [n = 10] were assessed by multiplexed analysis technology. Hierarchical Clustering Analysis, Principal Component Analysis, Random Forest Classification and Multinomial Logistic Regression models were used to segregate experimental groups. Based on Random Forest Classification, Multinomial Logistic Regression and Hierarchical Clustering Analysis models, IL-4, TNF-α and IL-12p70 were the best predictors of skin rejection and identified rejection well in advance of histopathological alterations. TNF-α and IL-12p70 were the best predictors of muscle rejection and also preceded histopathological alterations. Principal Component Analysis identified IL-1α, IL-18, IL-1β, and IL-4 as principal drivers of transplant rejection. Thus, inflammatory patterns associated with rejection are specific for the individual tissue and may be superior for early detection and targeted treatment of rejection.

Acute antibody-mediated rejection in pancreas and kidney transplantation

NARCIS (Netherlands)

Kort, Hanneke de

2013-01-01

In this thesis, acute rejection after kidney, simultaneous pancreas and kidney (SPKT), and islets of Langerhans transplantation was addressed. The focus is on acute antibody-mediated rejection (AMR) after transplantation and on a potential strategy using cellular immune modulation to prevent acute

Do nest light conditions affect rejection of parasitic eggs? A test of the light environment hypothesis

Czech Academy of Sciences Publication Activity Database

Honza, Marcel; Procházka, Petr; Morongová, Klára; Čapek, Miroslav; Jelínek, Václav

2011-01-01

Roč. 117, č. 6 (2011), s. 539-546 ISSN 0179-1613 R&D Projects: GA AV ČR IAA600930903; GA MŠk LC06073 Institutional research plan: CEZ:AV0Z60930519 Keywords : Acrocephalus arundinaceus * nest light conditions * egg recognition * Great reed warbler * cuckoo Subject RIV: EG - Zoology Impact factor: 2.008, year: 2011

Stray current induced corrosion in lightning rod cables of 525 kV power lines towers: a case study

International Nuclear Information System (INIS)

Wojcicki, F. R.; Negrisoli, M. E. M.; Franco, C. V.

2003-01-01

With the growth of several areas in modern society, the necessity to generate and carry electrical energy to big cities has greatly increased. Cables supported by power towers with galvanized steel foundation usually carry energy. As the foundations are underground they may cause high rates of corrosion. These are usually detected by a conventional potential measurement using a Cu/CuSO 4 reference electrode. It is believed that corrosion results from stray currents that flow through the ground to close the loop between neighboring towers. Stray currents originate in the lightning rod cables of the power line towers, induced by the strong electromagnetic and electric fields of the energized power lines. The intensity and direction of those currents were measured, indicating substantial values of both their AC and DC components. The potential of the tower ground system, measured in the perpendicular direction of the main axis of the power line, was plotted as a function of the distance to the tower base. The results clearly indicated the tendency to corrosive attack in the anodic towers as reflected by the slope of the plot, whereas no signs of corrosion could be found in the reverse slope, confirming the visual inspection of the foundation. The profile of the potential plots could be changed providing the electric insulation of the lightning rod cable. (Author) 8 refs

On active disturbance rejection based control design for superconducting RF cavities

Energy Technology Data Exchange (ETDEWEB)

Vincent, John; Morris, Dan; Usher, Nathan [National Superconducting Cyclotron Laboratory (NSCL), Michigan State University, East Lansing, MI 48824-1321 (United States); Gao, Zhiqiang, E-mail: z.gao@csuohio.edu [Center for Advanced Control Technologies, Fenn College of Engineering, Cleveland State University, Cleveland, OH 44115-2214 (United States); Zhao Shen; Nicoletti, Achille; Zheng Qinling [Center for Advanced Control Technologies, Fenn College of Engineering, Cleveland State University, Cleveland, OH 44115-2214 (United States)

2011-07-01

Superconducting RF (SRF) cavities are key components of modern linear particle accelerators. The National Superconducting Cyclotron Laboratory (NSCL) is building a 3 MeV/u re-accelerator (ReA3) using SRF cavities. Lightly loaded SRF cavities have very small bandwidths (high Q) making them very sensitive to mechanical perturbations whether external or self-induced. Additionally, some cavity types exhibit mechanical responses to perturbations that lead to high-order non-stationary transfer functions resulting in very complex control problems. A control system that can adapt to the changing perturbing conditions and transfer functions of these systems would be ideal. This paper describes the application of a control technique known as 'Active Disturbance Rejection Control' (ARDC) to this problem.

Endoparasites of Stray Dogs in Mashhad, Khorasan Razavi Province, Northeast Iran with Special Reference to Zoonotic Parasites

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Amir Adinezadeh

2013-09-01

Full Text Available Background: To find out different species of helminthes and blood/tissue proto­zoan parasites of stray dogs and their potential role for transmission of zoonotic species to human in Mashhad, Khorasan Razavi Province, northeast Iran, during 2008-2009.Methods: Totally, 100 stray dogs were selected among Mashhad municipal collection from different sites of the city. Internal organs were examined for any parasites. Helminthes were identified based on morphological characteristics. Smears prepared from peripheral blood as well as liver, spleen and any skin lesion were stained by Giemsa and examined microscopically. Samples obtained from spleen were aseptically cultured in three culture media including NNN, Schneider’s Drosophila (HIMEDIA and RPMI1640 (GIBCO for isolation of Leishmania spp. The titer of anti-Leishmania and anti-Toxoplasma antibodies were measured by direct agglutination test (DAT and indirect fluorescent antibody test (IFAT, respectively.Results: 84% of dogs were infected at least with one species of intestinal helminthes. The species of parasites and rate of infection were as follows: Taenia hydatigena (61%, Dipylidium caninum (46%, Mesocestoides lineatus (19%, Echinococcus granulosus (10%, Toxascaris leonina (53% and Toxocara canis (7%. Anti-Leishmania antibodies were detected by DAT in 8 dogs (8% at 1:320 titers and higher. Forty seven dogs (47% showed anti-Toxoplasma titer at 1:10 and 17 (17% showed titer of ≥1:100. No blood parasites were found in prepared blood smears.Conclusion: The high rate of parasitic infection and presence of zoonotic species

Reduction of ballistic spin scattering in a spin-FET using stray electric fields

International Nuclear Information System (INIS)

Nemnes, G A; Manolescu, A; Gudmundsson, V

2012-01-01

The quasi-bound states which appear as a consequence of the Rashba spin-orbit (SO) coupling, introduce a strongly irregular behavior of the spin-FET conductance at large Rashba parameter. Moreover, the presence of the bulk inversion asymmetry, i.e. the Dresselhaus SO coupling, may compromise the spin-valve effect even at small values of the Rashba parameter. However, by introducing stray electric fields in addition to the SO couplings, we show that the effect of the SO induced quasi-bound states can be tuned. The oscillations of the spin-resolved conductance become smoother and the control of the spin-FET characteristics becomes possible. For the calculations we employ a multi-channel scattering formalism, based on the R-matrix method extended to spin transport, in the presence of Rashba and Dresselhaus SO couplings.

Redox-Dependent Inflammation in Islet Transplantation Rejection

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Jessie M. Barra

2018-04-01

Full Text Available Type 1 diabetes is an autoimmune disease that results in the progressive destruction of insulin-producing pancreatic β-cells inside the islets of Langerhans. The loss of this vital population leaves patients with a lifelong dependency on exogenous insulin and puts them at risk for life-threatening complications. One method being investigated to help restore insulin independence in these patients is islet cell transplantation. However, challenges associated with transplant rejection and islet viability have prevented long-term β-cell function. Redox signaling and the production of reactive oxygen species (ROS by recipient immune cells and transplanted islets themselves are key players in graft rejection. Therefore, dissipation of ROS generation is a viable intervention that can protect transplanted islets from immune-mediated destruction. Here, we will discuss the newly appreciated role of redox signaling and ROS synthesis during graft rejection as well as new strategies being tested for their efficacy in redox modulation during islet cell transplantation.

Redox-Dependent Inflammation in Islet Transplantation Rejection

Science.gov (United States)

Barra, Jessie M.; Tse, Hubert M.

2018-01-01

Type 1 diabetes is an autoimmune disease that results in the progressive destruction of insulin-producing pancreatic β-cells inside the islets of Langerhans. The loss of this vital population leaves patients with a lifelong dependency on exogenous insulin and puts them at risk for life-threatening complications. One method being investigated to help restore insulin independence in these patients is islet cell transplantation. However, challenges associated with transplant rejection and islet viability have prevented long-term β-cell function. Redox signaling and the production of reactive oxygen species (ROS) by recipient immune cells and transplanted islets themselves are key players in graft rejection. Therefore, dissipation of ROS generation is a viable intervention that can protect transplanted islets from immune-mediated destruction. Here, we will discuss the newly appreciated role of redox signaling and ROS synthesis during graft rejection as well as new strategies being tested for their efficacy in redox modulation during islet cell transplantation. PMID:29740396

Anxious and angry rejection sensitivity, social withdrawal, and retribution in high and low ambiguous situations.

Science.gov (United States)

Zimmer-Gembeck, Melanie J; Nesdale, Drew

2013-02-01

Rejection sensitivity (RS) is a tendency to expect, perceive, and overreact to rejection. Our objective was to examine whether anxious and angry RS have specific associations with negative social reactions, and whether responses are intensified in situations of high rejection ambiguity. In two studies, youth (N = 464 and N = 371) reported their RS and anticipated responses to social scenarios. In Study 1, all scenarios portrayed overt rejection events. In Study 2, participants were randomly assigned to conditions portraying overt or ambiguous rejection. Greater rejection expectation was associated with more negative reactions to rejection. Moreover, as expected, anxiety about rejection was uniquely associated with withdrawal, and anger about rejection was uniquely associated with retribution (i.e., reactive aggression). In the second study, RS persons responded more negatively than others to both overt and high ambiguous rejections, but retribution was intensified among participants high in rejection expectation when rejection was ambiguous, and withdrawal was intensified among participants high in anxious RS in overt rejection situations. Consistent with the revised RS model, there are different patterns of emotions, cognitions, and behaviors in response to high and low ambiguous rejection events, which are heightened in youth sensitive to rejection. © 2012, Wiley Periodicals, Inc.

The legal status of cats in New Zealand: a perspective on the welfare of companion, stray, and feral domestic cats (Felis catus).

Science.gov (United States)

Farnworth, Mark J; Dye, Nicholson G; Keown, Natasha

2010-01-01

Pinpointing and safeguarding the welfare status of domestic cats is problematic, especially in New Zealand where cats are introduced predators with significant impact on indigenous fauna. Usually the identification of welfare status depends on conservational, legal, and public attitudes that are often contrasting. Cats may rapidly transgress definitions placed on them, confounding attempts to categorize them. In 1 generation, cats can move from a human-dependent state ("stray" or "companion") to wild ("feral"). Often this categorization uses arbitrary behavioral and or situational parameters; consequent treatment and welfare protection for these cats are similarly affected. Terminology used to describe cats is not equitable across research. However, the New Zealand Animal Welfare (Companion Cats) Code of Welfare 2007 seeks to create a new definition of the terms companion, stray, and feral. It distinguishes between cats who live within and without human social constructs. This legislation mandates that cats in human environments or indirectly dependent on humans cannot be classified as feral. Such definitions may prove vital when safeguarding the welfare of free-living domestic cats and cat colonies.

Associations between rejection sensitivity and mental health outcomes : A meta-analytic review

NARCIS (Netherlands)

Gao, S.; Assink, M.; Cipriani, A.; Lin, K.

2017-01-01

Rejection sensitivity is a personality disposition characterized by oversensitivity to social rejection. Using a three-level meta-analytic model, 75 studies were reviewed that examined associations between rejection sensitivity and five mental health outcomes: depression, anxiety, loneliness,

Behavioral and Personality Predictors of Acceptance and Rejection in University

Directory of Open Access Journals (Sweden)

Daniel Bartholomeu

Full Text Available Abstract: Acceptance and rejection in the group are related to both personality characteristics and social skills and most studies focus on children instead of college students. The objective of this study was to investigate whether acceptance and rejection would be more associated with personality tendencies, specifically socialization or social skills. We collected data from 187 college students attending the Physical Education (67% and Psychology (32% courses. The instruments were the sociometric test, the Factorial Scale of Socialization and the Social Skills Inventory. A moderating effect of gender in the relationship between assertiveness and acceptance and rejection to go out on college was observed. Social skills were better predictors of acceptance and social rejection in the university group.

Rejection of randomly coinciding events in Li{sub 2}{sup 100}MoO{sub 4} scintillating bolometers using light detectors based on the Neganov-Luke effect

Energy Technology Data Exchange (ETDEWEB)

Chernyak, D.M.; Danevich, F.A. [Institute for Nuclear Research, Kyiv (Ukraine); Dumoulin, L.; Marcillac, P. de; Marnieros, S.; Olivieri, E. [CSNSM, Univ. Paris-Sud, CNRS/IN2P3, Universite Paris-Saclay, Orsay (France); Giuliani, A.; Mancuso, M. [CSNSM, Univ. Paris-Sud, CNRS/IN2P3, Universite Paris-Saclay, Orsay (France); DISAT, Universita dell' Insubria, Como (Italy); Nones, C. [CEA Saclay, DSM/IRFU, Gif-sur-Yvette (France); Poda, D.V. [Institute for Nuclear Research, Kyiv (Ukraine); CSNSM, Univ. Paris-Sud, CNRS/IN2P3, Universite Paris-Saclay, Orsay (France); Tretyak, V.I. [Institute for Nuclear Research, Kyiv (Ukraine); INFN, Rome (Italy)

2017-01-15

Random coincidences of nuclear events can be one of the main background sources in low-temperature calorimetric experiments looking for neutrinoless double-beta decay, especially in those searches based on scintillating bolometers embedding the promising double-beta candidate {sup 100}Mo, because of the relatively short half-life of the two-neutrino double-beta decay of this nucleus. We show in this work that randomly coinciding events of the two-neutrino double-beta decay of {sup 100}Mo in enriched Li{sub 2}{sup 100}MoO{sub 4} detectors can be effectively discriminated by pulse-shape analysis in the light channel if the scintillating bolometer is provided with a Neganov-Luke light detector, which can improve the signal-to-noise ratio by a large factor, assumed here at the level of ∝750 on the basis of preliminary experimental results obtained with these devices. The achieved pile-up rejection efficiency results in a very low contribution, of the order of ∝6 x 10{sup -5} counts/(keV.kg.y), to the background counting rate in the region of interest for a large volume (∝90 cm{sup 3}) Li{sub 2}{sup 100}MoO{sub 4} detector. This background level is very encouraging in view of a possible use of the Li{sub 2}{sup 100}MoO{sub 4} solution for a bolometric tonne-scale next-generation experiment as that proposed in the CUPID project. (orig.)

Radiation therapy treatment of acute refractory renal allograft rejection

International Nuclear Information System (INIS)

Godinez, J.; Thisted, R.A.; Woodle, E.S.; Thistlethwaite, J.R.; Powers, C.; Haraf, D.

1996-01-01

Purpose: To evaluate the impact of the use of radiotherapy to preserve the renal graft in patients with recurrent graft rejection that failed to respond to medical treatment and identify risk factors to predict the probability of graft loss. Material and Methods: Between June 1989 and December 1995, 53 renal graft recipients were treated at our institution after experiencing several episodes of rejection. Rejection was defined as an unexplained, consecutive, daily rise in serum creatinine. Each episode was confirmed with renal biopsy. Patients who experienced rejection were initially treated with solu medrol bolus and prednisone. Patients with steroid-resistant or recurrent rejection received OKT3, polyclonal antilymphocyte antibody, FK506, or mycophenolate mofetil. Those who failed to respond to medical treatment were referred for radiotherapy. Treatment consisted of a dose of 600 cGy given in 3 or 4 fractions using 6 MV photons, AP or AP/PA. All patients underwent ultrasound kidney localization; a 2 cm margin was given around the kidney. Results: Median follow-up from the date of transplant to the last follow-up was 22 months (range 1-83 months), the median time from the date of transplant to the initiation of radiotherapy was 3 months, and the median time from the initiation of radiotherapy to the last follow up was 10 months (range 0.1 to 64 months). Of these 34 men and 19 women, median age of 3), Ninety-one percent were cadaveric transplant recipients., human leukocyte antigen matching on HLA-A and HLA-B (zero antigens in 26 patients/one or two shared antigens in 27 patients), HLA-DR locus (zero antigens in 34 patients/one or two shared antigens in 19 patients), transplant panel-reactive antibodies at transplantation (median PRA-Curr of 3% and median PRA-Max of 8%), number of acute rejection episodes, interval from the date of the transplant to the first rejection (median 1 month, range 5 days to 68 months), serum creatinine levels at the time of the first

Uptake of donor lymphocytes treated with 8-methoxypsoralen and ultraviolet A light by recipient dendritic cells induces CD4+CD25+Foxp3+ regulatory T cells and down-regulates cardiac allograft rejection

International Nuclear Information System (INIS)

Zheng, De-Hua; Dou, Li-Ping; Wei, Yu-Xiang; Du, Guo-Sheng; Zou, Yi-Ping; Song, Ji-Yong; Zhu, Zhi-Dong; Cai, Ming; Qian, Ye-Yong; Shi, Bing-Yi

2010-01-01

Extracorporeal photopheresis (ECP) is an effective immunomodulatory therapy and has been demonstrated to be beneficial for graft-vs-host disease and solid-organ allograft rejection. ECP involves reinfusion of a patient's autologous peripheral blood leukocytes treated ex vivo with 8-methoxypsoralen and UVA light radiation (PUVA). Previous studies focused only on ECP treatment of recipient immune cells. Our study is the first to extend the target of ECP treatment to donor immune cells. The results of in vitro co-culture experiments demonstrate uptake of donor PUVA-treated splenic lymphocytes (PUVA-SPs) by recipient immature dendritic cells (DCs). Phagocytosis of donor PUVA-SPs does not stimulate phenotype maturation of recipient DCs. In the same co-culture system, donor PUVA-SPs enhanced production of interleukin-10 and interferon-γ by recipient DCs and impaired the subsequent capability of recipient DCs to stimulate recipient naive T cells. Phagocytosis of donor PUVA-SP (PUVA-SP DCs) by recipient DCs shifted T-cell responses in favor of T helper 2 cells. Infusion of PUVA-SP DCs inhibited cardiac allograft rejection in an antigen-specific manner and induced CD4 + CD25 high Foxp3 + regulatory T cells. In conclusion, PUVA-SP DCs simultaneously deliver the donor antigen and the regulatory signal to the transplant recipient, and thus can be used to develop a novel DC vaccine for negative immune regulation and immune tolerance induction.

Higher boron rejection with a new TFC forward osmosis membrane

KAUST Repository

Valladares Linares, Rodrigo; Li, Zhenyu; Sarp, Sarper; Park, Y. G.; Amy, Gary L.; Vrouwenvelder, Johannes S.

2014-01-01

Due to the stringent limits for boron in drinking and irrigation water, water treatment facilities have to incur additional treatment to remove boron down to a safe concentration. Forward osmosis (FO) is a membrane technology that may reduce the energy required to remove boron present in seawater. In direct FO desalination hybrid systems, fresh water is recovered from seawater using a recoverable draw solution, FO membranes are expected to show high boron rejection. This study focuses on determining the boron rejection capabilities of a new generation thin-film composite (TFC) FO membrane compared to a first generation cellulose triacetate (CTA) FO membrane. The effects of water permeate flux, membrane structure, draw solute charge, and reverse solute flux on boron rejection were determined. For TFC and CTA FO membranes, experiments showed that when similar operating conditions are applied (e.g. membrane type and draw solute type) boron rejection decreases with increase in permeate flux. Reverse draw solute flux and membrane fouling have no significant impact on boron rejection. Compared to the first generation CTA FO membrane operated at the same conditions, the TFC FO membrane showed a 40% higher boron rejection capability and a 20% higher water flux. This demonstrates the potential for boron removal for new generation TFC FO membranes. © 2014 © 2014 Balaban Desalination Publications. All rights reserved.

Higher boron rejection with a new TFC forward osmosis membrane

KAUST Repository

Valladares Linares, Rodrigo

2014-07-17

Due to the stringent limits for boron in drinking and irrigation water, water treatment facilities have to incur additional treatment to remove boron down to a safe concentration. Forward osmosis (FO) is a membrane technology that may reduce the energy required to remove boron present in seawater. In direct FO desalination hybrid systems, fresh water is recovered from seawater using a recoverable draw solution, FO membranes are expected to show high boron rejection. This study focuses on determining the boron rejection capabilities of a new generation thin-film composite (TFC) FO membrane compared to a first generation cellulose triacetate (CTA) FO membrane. The effects of water permeate flux, membrane structure, draw solute charge, and reverse solute flux on boron rejection were determined. For TFC and CTA FO membranes, experiments showed that when similar operating conditions are applied (e.g. membrane type and draw solute type) boron rejection decreases with increase in permeate flux. Reverse draw solute flux and membrane fouling have no significant impact on boron rejection. Compared to the first generation CTA FO membrane operated at the same conditions, the TFC FO membrane showed a 40% higher boron rejection capability and a 20% higher water flux. This demonstrates the potential for boron removal for new generation TFC FO membranes. © 2014 © 2014 Balaban Desalination Publications. All rights reserved.

15 CFR 700.13 - Acceptance and rejection of rated orders.

Science.gov (United States)

2010-01-01

... order and transmit the acceptance or rejection in writing (hard copy), or in electronic format, within... rejection, pursuant to paragraphs (b) and (c) of this section, in writing (hard copy) or electronic format...

Model of inter-cell interference phenomenon in 10 nm magnetic tunnel junction with perpendicular anisotropy array due to oscillatory stray field from neighboring cells

Science.gov (United States)

Ohuchida, Satoshi; Endoh, Tetsuo

2018-06-01

In this paper, we propose a new model of inter-cell interference phenomenon in a 10 nm magnetic tunnel junction with perpendicular anisotropy (p-MTJ) array and investigated the interference effect between a program cell and unselected cells due to the oscillatory stray field from neighboring cells by Landau–Lifshitz–Gilbert micromagnetic simulation. We found that interference brings about a switching delay in a program cell and excitation of magnetization precession in unselected cells even when no programing current passes through. The origin of interference is ferromagnetic resonance between neighboring cells. During the interference period, the precession frequency of the program cell is 20.8 GHz, which synchronizes with that of the theoretical precession frequency f = γH eff in unselected cells. The disturbance strength of unselected cells decreased to be inversely proportional to the cube of the distance from the program cell, which is in good agreement with the dependence of stray field on the distance from the program cell calculated by the dipole approximation method.

48 CFR 814.404-2 - Rejection of individual bids.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Rejection of individual... Rejection of individual bids. (a) When a contracting officer finds a bid that is being considered for an... nonresponsive an individual bid that is not in compliance with the Government's bid acceptance time, since...

Effects of composite mango ( Mangifera indica ) fruit reject meal on ...

African Journals Online (AJOL)

Effects of composite mango ( Mangifera indica ) fruit reject meal on growth performance, digestibility and economics of production of rabbits. ... The experiment was conducted to determine the effect of mango fruit reject ... HOW TO USE AJOL.

Family and community rejection and a Congolese led mediation intervention to reintegrate rejected survivors of sexual violence in Eastern Democratic Republic of Congo.

Science.gov (United States)

Kohli, Anjalee; Tosha, Maphie; Ramazani, Paul; Safari, Octave; Bachunguye, Richard; Zahiga, Isaya; Iragi, Aline; Glass, Nancy

2013-01-01

Our purpose in this study is to describe the multiple and inter-related health, economic, and social reasons for rejection and to provide an example of a Congolese-led family mediation program to reintegrate survivors into their families. We conducted this study in Eastern Democratic Republic of Congo (DRC) and included two focus group discussions and twenty-seven interviews. Rejection extends beyond physical dislocation to include economic and social aspects. Family mediation is a process requiring knowledge of traditions and norms. Understanding the context of rejection and supporting promising local reintegration efforts will likely improve health, economic, and social outcomes for the survivor, her family, and her community.

Refusals and Rejections: Designing Messages to Serve Multiple Goals.

Science.gov (United States)

Saeki, Mimako; O'Keefe, Barbara J.

1994-01-01

Tests a rational model of the elaboration of themes found in rejection messages, using Japanese and American participants. Finds partial support for the initial rational model but notes two key revisions: identifies two new themes in rejection messages and suggests substantial differences in the way Americans and Japanese elaborate themes to serve…

Experimental Verification of a Harmonic-Rejection Mixing Concept using Blind Interference Canceling

NARCIS (Netherlands)

Moseley, N.A.; Klumperink, Eric A.M.; Nauta, Bram

2008-01-01

Abstract—This paper presents the first practical experiments on a harmonic rejection downconverter, which offers up to 75 dB of harmonic rejection, without an RF filter. The downconverter uses a two-stage approach; the first stage is an analog multipath/ multi-phase harmonic rejection mixer followed

Band rejection filter for measurement of electron cyclotron emission during electron cyclotron heating

International Nuclear Information System (INIS)

Iwase, Makoto; Ohkubo, Kunizo; Kubo, Shin; Idei, Hiroshi.

1996-05-01

For the measurement of electron cyclotron emission from the high temperature plasma, a band rejection filter in the range of 40-60 GHz is designed to reject the 53.2 GHz signal with large amplitude from the gyrotron for the purpose of plasma electron heating. The filter developed with ten sets of three quarters-wavelength coupled by TE 111 mode of tunable resonant cavity has rejection of 50 dB and 3 dB bandwidth of 500 MHz. The modified model of Tschebysheff type for the prediction of rejection is proposed. It is confirmed that the measured rejection as a function of frequency agrees well with the experimental results for small coupling hole, and also clarified that the rejection ratio increases for the large coupling hole. (author)

Delayed allogeneic skin graft rejection in CD26-deficient mice.

Science.gov (United States)

Zhao, Xiangli; Zhang, Kai; Daniel, Peter; Wisbrun, Natali; Fuchs, Hendrik; Fan, Hua

2018-03-23

Organ transplantation is an effective therapeutic tool for treating many terminal diseases. However, one of the biggest challenges of transplantation is determining how to achieve the long-term survival of the allogeneic or xenogeneic transplant by, for example, preventing transplant rejection. In the current study, CD26 gene-knockout mice were used to investigate the potential role of CD26/dipeptidyl peptidase-4 (DPPIV) in allogeneic skin graft rejection by tail-skin transplantation. Compared with wild-type (CD26 +/+ ) counterparts, CD26 -/- mice showed reduced necrosis of grafts and delayed graft rejection after skin transplantation. Concentrations of serum IgG, including its subclasses IgG1 and IgG2a, were significantly reduced in CD26 -/- mice during graft rejection. Moreover, after allogeneic skin transplantation, the secretion levels of the cytokines IFN-γ, IL-2, IL-6, IL-4, and IL-13 were significantly reduced, whereas the level of the cytokine IL-10 was increased in the serum of CD26 -/- mice compared with that in the serum of CD26 +/+ mice. Additionally, the concentration of IL-17 in serum and the percentage of cells secreting IL-17 in mouse peripheral blood lymphocytes (MPBLs) were both significantly lower, while the percentage of regulatory T cells (Tregs) was significantly higher in MPBLs of CD26 -/- mice than in those of CD26 +/+ mice. Furthermore, a lower percentage of CD8 + T cells in MPBLs and fewer infiltrated macrophages and T cells in graft tissues of CD26 -/- mice were detected during graft rejection. These results indicate that CD26 is involved in allogeneic skin graft rejection and provides another hint that CD26 deficiency leads to less rejection due to lower activation and proliferation of host immune cells.

PREVENTION AND TREATMENT OF REJECTION AFTER SIMULTANEOUS PANCREAS-KIDNEY TRANSPLANTATION

Institute of Scientific and Technical Information of China (English)

Lei Yang; Yong-feng Liu; Shu-rong Liu; Gang Wu; Jia-lin Zhang; Yi-man Meng; Shao-wei Shong; Gui-chen Li

2005-01-01

Objective To explore methods of preventing and reversing rejection after simultaneous pancreas-kidney (SPK) tran splantation. Methods Seventeen patients underwent SPK transplantation from September 1999 to September 2003 were reviewed retrospectively. Immunosuppression was achieved by a triple drug regimen consisting of cyclosporine, mycophenolate mofteil (MMF), and steroids. Three patients were treated with anti-CD3 monoclone antibody (OKT3, 5 mg· d-1) for induction therapy for a mean period of 5-7 days. One patients received IL-2 receptor antibodies (daclizumab) in a dose of 1 mg· kg-1 on the day of transplant and the 5th day posttransplant. One patient was treated with both OKT3 and daclizumab for induction. Results No primary non-functionality of either kidney or pancreas occurred in this series of transplantations. Function of all the kidney grafts recovered within 2 to 4 days after transplantation. The level of serum creatinine was 94 ± 11 μmol/L on the 7th day posttransplant. One patient experienced the accelerated rejection, resulting in the resection of the pancreas and kidney grafts because of the failure of conservative therapy. The incidence of the first rejection episodes at 3 months was 47.1% (8/17). Only the kidney was involved in 35.3% (6/17); and both the pancreas and kidney were involved in 11.8% (2/17). All these patients received a high-dose pulse of methylprednisone (0.5 g·d-1) for 3 days. OKT3 (0.5 mg·d-1) was administered for 7-10 days in two patients with both renal and pancreas rejection. All the grafts were successfully rescued. Conclusion Rejection, particularly acute rejection, is the major cause influencing graft function in SPK transplantation. Monitoring renal function and pancreas exocrine secretion, and reasonable application of immunosuppressants play important roles in the diagnosis and treatment of rejection.

The stylar 120 kDa glycoprotein is required for S-specific pollen rejection in Nicotiana.

Science.gov (United States)

Hancock, C Nathan; Kent, Lia; McClure, Bruce A

2005-09-01

S-RNase participates in at least three mechanisms of pollen rejection. It functions in S-specific pollen rejection (self-incompatibility) and in at least two distinct interspecific mechanisms of pollen rejection in Nicotiana. S-specific pollen rejection and rejection of pollen from Nicotiana plumbaginifolia also require additional stylar proteins. Transmitting-tract-specific (TTS) protein, 120 kDa glycoprotein (120K) and pistil extensin-like protein III (PELP III) are stylar glycoproteins that bind S-RNase in vitro and are also known to interact with pollen. Here we tested whether these glycoproteins have a direct role in pollen rejection. 120K shows the most polymorphism in size between Nicotiana species. Larger 120K-like proteins are often correlated with S-specific pollen rejection. Sequencing results suggest that the polymorphism primarily reflects differences in glycosylation, although indels also occur in the predicted polypeptides. Using RNA interference (RNAi), we suppressed expression of 120K to determine if it is required for S-specific pollen rejection. Transgenic SC N. plumbaginifolia x SI Nicotiana alata (S105S105 or SC10SC10) hybrids with no detectable 120K were unable to perform S-specific pollen rejection. Thus, 120K has a direct role in S-specific pollen rejection. However, suppression of 120K had no effect on rejection of N. plumbaginifolia pollen. In contrast, suppression of HT-B, a factor previously implicated in S-specific pollen rejection, disrupts rejection of N. plumbaginifolia pollen. Thus, S-specific pollen rejection and rejection of N. plumbaginifolia pollen are mechanistically distinct, because they require different non-S-RNase factors.

Active disturbance rejection controller for chemical reactor

International Nuclear Information System (INIS)

Both, Roxana; Dulf, Eva H.; Muresan, Cristina I.

2015-01-01

In the petrochemical industry, the synthesis of 2 ethyl-hexanol-oxo-alcohols (plasticizers alcohol) is of high importance, being achieved through hydrogenation of 2 ethyl-hexenal inside catalytic trickle bed three-phase reactors. For this type of processes the use of advanced control strategies is suitable due to their nonlinear behavior and extreme sensitivity to load changes and other disturbances. Due to the complexity of the mathematical model an approach was to use a simple linear model of the process in combination with an advanced control algorithm which takes into account the model uncertainties, the disturbances and command signal limitations like robust control. However the resulting controller is complex, involving cost effective hardware. This paper proposes a simple integer-order control scheme using a linear model of the process, based on active disturbance rejection method. By treating the model dynamics as a common disturbance and actively rejecting it, active disturbance rejection control (ADRC) can achieve the desired response. Simulation results are provided to demonstrate the effectiveness of the proposed method

Active disturbance rejection controller for chemical reactor

Energy Technology Data Exchange (ETDEWEB)

Both, Roxana; Dulf, Eva H.; Muresan, Cristina I., E-mail: roxana.both@aut.utcluj.ro [Technical University of Cluj-Napoca, 400114 Cluj-Napoca (Romania)

2015-03-10

In the petrochemical industry, the synthesis of 2 ethyl-hexanol-oxo-alcohols (plasticizers alcohol) is of high importance, being achieved through hydrogenation of 2 ethyl-hexenal inside catalytic trickle bed three-phase reactors. For this type of processes the use of advanced control strategies is suitable due to their nonlinear behavior and extreme sensitivity to load changes and other disturbances. Due to the complexity of the mathematical model an approach was to use a simple linear model of the process in combination with an advanced control algorithm which takes into account the model uncertainties, the disturbances and command signal limitations like robust control. However the resulting controller is complex, involving cost effective hardware. This paper proposes a simple integer-order control scheme using a linear model of the process, based on active disturbance rejection method. By treating the model dynamics as a common disturbance and actively rejecting it, active disturbance rejection control (ADRC) can achieve the desired response. Simulation results are provided to demonstrate the effectiveness of the proposed method.

T-regulatory cells in chronic rejection versus stable grafts.

Science.gov (United States)

Al-Wedaie, Fatima; Farid, Eman; Tabbara, Khaled; El-Agroudy, Amgad E; Al-Ghareeb, Sumaya M

2015-04-01

Studying regulatory T cells in kidney allograft acceptance versus chronic rejection may help in the understanding of more mechanisms of immune tolerance and, in the future, may enable clinicians to induce immune tolerance and decrease the use of immunosuppressive drugs. The aim of the current study was to evaluate regulatory T cells in kidney transplant patients with stable graft versus transplant with biopsy-proven chronic rejection. The 3 groups that were studied included: kidney transplanted patients with no rejection episodes (n = 43); transplanted patients with biopsy-proven renal rejection (n = 27); and healthy age-matched nontransplanted individuals as controls (n = 42).The percentage of regulatory T cells (CD4+CD25+Foxp3+) in blood was determined by flow cytometry. The regulatory T cell percentage was significantly lower in chronic rejection patients than control or stable graft groups. No significant difference was observed in regulatory T cell percentage between the stable graft and control groups. In the stable graft group, patients on rapamycin had a significantly higher regulatory T cell percentage than patients on cyclosporine. No effect of donor type, infection, or duration after transplant was observed on regulatory T cell percentage. The results of the current study are consistent with previous studies addressing the function of regulatory T cells in inducing immunotolerance after kidney transplant. Considering the established role of regulatory T cells in graft maintenance and our observation of high regulatory T cell percentage in patients receiving rapamycin than cyclosporine, we recommend including rapamycin when possible in immunosuppressive protocols. The findings from the current study on the chronic rejection group support ongoing research of having treatment with regulatory T cells, which may constitute a novel, efficient antirejection therapy in the future.

48 CFR 14.404-2 - Rejection of individual bids.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Rejection of individual... of individual bids. (a) Any bid that fails to conform to the essential requirements of the invitation... total price of the bid, but the prices for individual line items as well. (g) Any bid may be rejected if...

Compensatory deficits following rejection: the role of social anxiety in disrupting affiliative behavior.

Science.gov (United States)

Mallott, Michael A; Maner, Jon K; DeWall, Nathan; Schmidt, Norman B

2009-01-01

Managing perceived or actual social rejection is an important facet of meeting basic needs for affiliation. Social anxiety disorder (SAD) is characterized by significant distress and debilitation relating to affiliation and recent work suggests higher levels of social anxiety symptoms may adversely affect responses to social rejection. This study examined emotional and behavioral responding to a social rejection stressor to explore whether social anxiety moderates the effects of social rejection on prosocial compensatory behaviors. Individuals (N=37) evaluated on social anxiety symptoms were assigned to either a social rejection condition or control condition. Consistent with expectation, rejection promoted renewed interest in connecting with sources of positive social interaction among participants low in social anxiety. Participants with higher levels of social anxiety, however, failed to react to rejection in a positive or prosocial manner and exhibited some evidence of negative social responses. Such differential compensatory responding could have important implications for the genesis, maintenance, and treatment of SAD.

Bone marrow-derived T lymphocytes responsible for allograft rejection

International Nuclear Information System (INIS)

Senjanovic, M.; Marusic, M.

1984-01-01

Lethally irradiated mice reconstituted with syngeneic bone marrow cells were grafted with allogeneic skin grafts 6-7 weeks after irradiation and reconstitution. Mice with intact thymuses rejected the grafts whereas the mice thymectomized before irradiation and reconstitution did not. Thymectomized irradiated mice (TIR mice) reconstituted with bone marrow cells from donors immune to the allografts rejected the grafts. Bone marrow cells from immunized donors, pretreated with Thy 1.2 antibody and C', did not confer immunity to TIR recipients. To determine the number of T lymphocytes necessary for the transfer of immunity by bone marrow cells from immunized donors, thymectomized irradiated mice were reconstituted with nonimmune bone marrow cells treated with Thy 1.2 antibody and C' and with various numbers of splenic T lymphocytes from nonimmune and immune donors. Allogeneic skin graft rejection was obtained with 10(6) nonimmune or 10(4) immune T cells. The effect of immune T cells was specific: i.e., immune T cells accelerated only rejection of the relevant skin grafts whereas against a third-party skin grafts acted as normal T lymphocytes

Information about radiographic films rejects of dental x-rays

International Nuclear Information System (INIS)

Cezimbra, M.R.; Bernarsiuk, M.E.; Bauer V, E.

1996-01-01

The purpose of this research was to qualify and quantify the number of dental x-ray films rejected in a Porto Alegre clinic. As we analyzed the captured data, it was concluded that, our of 1066 peri-apical films, we had a total percentage of 4.5% in relation to the total of the exams made. This 4.5% consists of the following rejects: placement, patient movement, technical errors, diaphragm, too much clarity in the result, double exposure, prolongation, shortness, darkened for not have been shot, superposed film. Because of that, the rejection, due to the bad placement of the film, is the one with the larger percentage value, i.e., 1.22% of the 4.5%. With the knowledge of the types of rejects and their causes, it was possible to correct some sources of systematic errors minimizing the repetition of the exams, saving costs, time and diminishing the ionizing radiation exposure for the patient, odontologist and his technical staff, which will be proved. (authors). 4 refs., 1 tab

Failure to diagnose cardiac treatment rejection with Tc99m-PYP images

International Nuclear Information System (INIS)

McKillop, J.H.; McDougall, I.R.; Goris, M.L.; Mason, J.W.; Reitz, B.A.

1981-01-01

The possibility of diagnosing transplant rejection using Tc-99m-PYP imaging was examined in 12 cardiac transplant recipients. Two patients were studied on two occasions. The presence or absence of active rejection was established by endomyocardial biopsy. The intensity and pattern of myocardial uptake of the tracer did not differ significantly in the two patients studied at the time of rejection compared to the remainder. It is concluded that a single Tc-99m-PYP study cannot be used to diagnose cardiac transplant rejection

Improvement of sensitivity in high-resolution Rutherford backscattering spectroscopy

International Nuclear Information System (INIS)

Hashimoto, H.; Nakajima, K.; Suzuki, M.; Kimura, K.; Sasakawa, K.

2011-01-01

The sensitivity (limit of detection) of high-resolution Rutherford backscattering spectroscopy (HRBS) is mainly determined by the background noise of the spectrometer. There are two major origins of the background noise in HRBS, one is the stray ions scattered from the inner wall of the vacuum chamber of the spectrometer and the other is the dark noise of the microchannel plate (MCP) detector which is commonly used as a focal plane detector of the spectrometer in HRBS. In order to reject the stray ions, several barriers are installed inside the spectrometer and a thin Mylar foil is mounted in front of the detector. The dark noise of the MCP detector is rejected by the coincidence measurement with the secondary electrons emitted from the Mylar foil upon the ion passage. After these improvements, the background noise is reduced by a factor of 200 at a maximum. The detection limit can be improved down to 10 ppm for As in Si at a measurement time of 1 h under ideal conditions.

Acute Hepatic Allograft Rejection in Pediatric Recipients: Effective Factors.

Science.gov (United States)

Dehghani, S M; Shahramian, I; Afshari, M; Bahmanyar, M; Ataollahi, M; Sargazi, A

2018-01-01

Acute cellular rejection (ACR), a reversible process, can affect the graft survival. To evaluate the relation between ACR and clinical factors in recipients of allograft liver transplantation. 47 recipients of liver were consecutively enrolled in a retrospective study. Their information were retrieved from their medical records and analyzed. Of the 47 recipients, 38 (81%) experienced acute rejection during 24 months of the transplantation. None of the studied factors for occurring transplant rejection, i.e ., blood groups, sex, age, familial history of disease, receiving drugs and blood products, type of donor, Child score, and Child class, was not found to be significant. During a limited follow-up period, we did not find any association between ACR and suspected risk factors.

Study of Background Rejection Systems for the IXO Mission.

Science.gov (United States)

Laurent, Philippe; Limousin, O.; Tatischeff, V.

2009-01-01

The scientific performances of the IXO mission will necessitate a very low detector background level. This will imply thorough background simulations, and efficient background rejection systems. It necessitates also a very good knowledge of the detectors to be shielded. In APC, Paris, and CEA, Saclay, we got experience on these activities by conceiving and optimising in parallel the high energy detector and the active and passive background rejection system of the Simbol-X mission. Considering that this work may be naturally extended to other X-ray missions, we have initiated with CNES a R&D project on the study of background rejection systems mainly in view the IXO project. We will detail this activity in the poster.

Harmonics rejection in pixelated interferograms using spatio-temporal demodulation.

Science.gov (United States)

Padilla, J M; Servin, M; Estrada, J C

2011-09-26

Pixelated phase-mask interferograms have become an industry standard in spatial phase-shifting interferometry. These pixelated interferograms allow full wavefront encoding using a single interferogram. This allows the study of fast dynamic events in hostile mechanical environments. Recently an error-free demodulation method for ideal pixelated interferograms was proposed. However, non-ideal conditions in interferometry may arise due to non-linear response of the CCD camera, multiple light paths in the interferometer, etc. These conditions generate non-sinusoidal fringes containing harmonics which degrade the phase estimation. Here we show that two-dimensional Fourier demodulation of pixelated interferograms rejects most harmonics except the complex ones at {-3(rd), +5(th), -7(th), +9(th), -11(th),…}. We propose temporal phase-shifting to remove these remaining harmonics. In particular, a 2-step phase-shifting algorithm is used to eliminate the -3(rd) and +5(th) complex harmonics, while a 3-step one is used to remove the -3(rd), +5harmonics. © 2011 Optical Society of America

Sensitivity of scintigraphy with 111In-lymphocytes for detection of cardiac allograft rejection

International Nuclear Information System (INIS)

Eisenberg, S.B.; Eisen, H.J.; Sobel, B.E.; Bergmann, S.R.; Bolman, R.M. III

1988-01-01

We recently demonstrated the feasibility of noninvasive detection of cardiac allograft rejection after administration of indium-111-labeled lymphocytes. To determine the sensitivity and specificity of the technique, as well as its value for delineating the severity of rejection, we studied 16 dogs with heterotopic thoracic cardiac allografts. Five animals were evaluated while exposed to immunosuppressive agents. Animals were scanned sequentially after administration of 100-400 microCi of indium-111-labeled autologous lymphocytes. Myocardial lymphocyte infiltration was expressed as the indium excess (IE), defined as the ratio of indium activity of the transplant or native heart compared with that in blood. Scintigraphic results were compared with characteristics of simultaneously obtained endomyocardial biopsies. Among 17 biopsy documented episodes of rejection, 16 were detected scintigraphically. Among 18 biopsies with no evidence of rejection, scintigraphy was uniformly negative. Thus, the sensitivity and specificity of scintigraphy were 94 and 100%, respectively. Biopsies graded as showing no rejection were associated with an IE of 0.3 +/- 0.5 (+/- SD); those graded as mild, 2.8 +/- 1.7; those as moderate, 10.7 +/- 7.2; and those graded as indicative of severe rejection, 14.2 +/- 4.5. Thus, scintigraphy with indium-111-labeled lymphocytes sensitively and specifically detects cardiac allograft rejection and delineates the intensity of the rejection process. It should be useful clinically for assessing potential allograft rejection noninvasively

Egg rejection behavior in a population exposed to parasitism: Village Weavers on Hispaniola

Science.gov (United States)

Cruz, A.; Prather, J.W.; Wiley, J.W.; Weaver, P.F.

2008-01-01

In contrast to African Village Weavers (Ploceus cucullatus) that are parasitized by Diederik Cuckoos (Chrysococcyx caprius), introduced weavers on Hispaniola existed without parasitism for at least 2 centuries until the arrival of the Shiny Cowbird (Molothrus bonariensis) in the 1970s. Cruz and Wiley (1989) found that Hispaniolan weavers had a lower rejection rate of foreign eggs than African populations. Subsequently, Robert and Sorci (1999) and Lahti (2005, 2006) found that acceptance of dissimilar eggs is not characteristic of the species throughout its Hispaniolan range. In 1999-2002, we studied egg rejection in Hispaniolan weavers on a broad regional scale. Rejection increased as experimental eggs became increasingly different from the host eggs. Rejection rates for mimetic eggs, different color eggs, different-spotting eggs, and cowbird eggs was 23.2%, 33.3%, 61.5%, and 85.3%, respectively, with higher rejection of cowbird eggs in areas where cowbirds were observed. Although rejection is likely to have a genetic component, the differences could be due to phenotypic plasticity. Plasticity in egg rejection may be expected, given the potential cost of rejection and the spatiotemporal distribution of cowbirds. Thus, egg rejection has not necessarily decreased in Hispaniolan weavers, but it may act in a plastic manner, increasing where cowbirds are present. ?? The Author 2008. Published by Oxford University Press on behalf of the International Society for Behavioral Ecology. All rights reserved.

Message Collision Avoidance Protocols for Detecting Stray Nodes in a Scuba Diving Group Using Ultrasonic Multi-Hop Message Communication

Directory of Open Access Journals (Sweden)

Shinya Kaido

2017-12-01

Full Text Available Recent years have seen a growing interest in underwater communication and some progress has been made in this area. However, underwater communication is still immature compared with terrestrial communication. A prime reason for this is that the underwater environment is intrinsically not suitable for propagation of electric waves. Instead, ultrasonic waves are mainly used for underwater communication. Since ultrasonic waves cannot provide sufficient communication speed or capacity, they cannot use existing network technologies, which assume use of radio waves. In particular, communication in shallow water is still an uncharted territory. Few communication technologies are employed in environments where people enjoy scuba diving. This paper addresses problems faced by recreational scuba divers. It proposes constructing an ad hoc mesh-shaped network between divers within a group and use ultrasonic waves as transmission media in order to enable the detection of a stray diver. It also proposes a communication protocol in which messages are relayed in multiple hops, and a message collision avoidance method, which is intended to reduce the rate of packet loss caused by message propagation delay. We have implemented the proposed methods in a network simulator, and compared them with an existing communication method that has no message collision avoidance function, in terms of the packet loss rate, the stray driver detection rate, and the rate of the ability to communicate in multiple hops.

What Do They Have That We Don't Have? Local Libraries and Distance Students: Why Do Students Stray and Can We Get Them Back?

Science.gov (United States)

Behr, Michele; LaDell-Thomas, Julie

2014-01-01

A significant number of distance students report they "stray" from their home universities by using local libraries, despite the fact that distance education librarians work hard to provide customized resources and services tailored to their programs and needs. Are public libraries and special libraries able to meet the research needs of…

Crosslinked cellulose thin film composite nanofiltration membranes with zero salt rejection

KAUST Repository

Puspasari, Tiara

2015-05-14

We report a new synthetic route of fabricating regenerated cellulose nanofiltration membranes. The membranes are composite membranes with a thin selective layer of cellulose, which was prepared by regeneration of trimethylsilyl cellulose (a hydrophobic cellulose derivative) film followed by crosslinking. Filtration experiments using mixtures of sugar and sodium chloride showed that solutes above 300 Da were highly rejected whereas practically no rejection was observed for NaCl. This is a big advantage for a complete desalination as the existing commercial nanofiltration membranes typically exhibit NaCl rejection in the range of 30–60%. Membranes with zero NaCl rejection are required for recovery and purification applications in food, chemical and pharmaceutical industry.

Increase of peripheral Th17 lymphocytes during acute cellular rejection in liver transplant recipients.

Science.gov (United States)

Fan, Hua; Li, Li-Xin; Han, Dong-Dong; Kou, Jian-Tao; Li, Ping; He, Qiang

2012-12-15

Although many human inflammatory and autoimmune diseases were previously considered to be mediated by T helper type 1 (Th1) cells, the recently described Th17 cells play dominant roles in several of these diseases. We and others speculated that allograft rejection after organ transplantation may also involve Th17 cells. Episodes of acute rejection occur in 30% of liver transplants. This study aimed to determine the frequency of circulating Th17 cells in patients who had received liver transplants for benign end-stage liver disease and to identify any association between acute rejection episodes and levels of Th17 cells in the peripheral blood. A prospective study compared Th17 cells from 76 consecutive benign end-stage liver disease patients who had undergone orthotopic liver transplantation from 2007 to 2011 with those from 20 age-matched healthy individuals. Peripheral blood samples were collected at different time points within one year after transplant. Blood samples and liver biopsies were also collected at the diagnosis of acute rejection. Percentages of circulating CD4+IL-17+ cells were measured by flow cytometry. The transplant patients were classified into two groups: a rejection group consisting of 17 patients who had an episode of acute rejection, and a non-rejection group comprising the remaining 59 patients with no acute rejection episodes. Percentages of circulating Th17 cells were compared between the two groups and controls. The levels of circulating CD4+IL-17+ T cells in the rejection group were higher during acute rejection than those in the non-rejection group (2.56+/-0.43% versus 1.79+/-0.44%, Pblood was positively correlated with the rejection activity index (r=0.79, P=0.0002). Circulating Th17 cells may be useful as a surrogate marker for predicting acute rejection in liver transplant recipients.

Rejection thresholds in solid chocolate-flavored compound coating.

Science.gov (United States)

Harwood, Meriel L; Ziegler, Gregory R; Hayes, John E

2012-10-01

Classical detection thresholds do not predict liking, as they focus on the presence or absence of a sensation. Recently however, Prescott and colleagues described a new method, the rejection threshold, where a series of forced choice preference tasks are used to generate a dose-response function to determine hedonically acceptable concentrations. That is, how much is too much? To date, this approach has been used exclusively in liquid foods. Here, we determined group rejection thresholds in solid chocolate-flavored compound coating for bitterness. The influences of self-identified preferences for milk or dark chocolate, as well as eating style (chewers compared to melters) on rejection thresholds were investigated. Stimuli included milk chocolate-flavored compound coating spiked with increasing amounts of sucrose octaacetate, a bitter and generally recognized as safe additive. Paired preference tests (blank compared to spike) were used to determine the proportion of the group that preferred the blank. Across pairs, spiked samples were presented in ascending concentration. We were able to quantify and compare differences between 2 self-identified market segments. The rejection threshold for the dark chocolate preferring group was significantly higher than the milk chocolate preferring group (P= 0.01). Conversely, eating style did not affect group rejection thresholds (P= 0.14), although this may reflect the amount of chocolate given to participants. Additionally, there was no association between chocolate preference and eating style (P= 0.36). Present work supports the contention that this method can be used to examine preferences within specific market segments and potentially individual differences as they relate to ingestive behavior. This work makes use of the rejection threshold method to study market segmentation, extending its use to solid foods. We believe this method has broad applicability to the sensory specialist and product developer by providing a

Pharmacologic strategies in the prevention and treatment of corneal transplant rejection.

Science.gov (United States)

Tabbara, Khalid F

2008-06-01

Corneal transplantation remains one of the most successful organ transplantation procedures in humans. The unique structure of the cornea, with its absence of blood vessels and corneal lymphatic, allows the survival of corneal allograft. Recent advances in sutures, storage media, microsurgical instrumentation, and new pharmacological strategies have greatly improved the success of corneal transplantation and the prevention of corneal allograft rejection. Our strategies in the management and prevention of corneal graft rejection can modify and improve the survival of corneal allografts. Preoperative evaluation, understanding the risk factors, and management of ocular surface disorders may greatly improve the survival of the corneal transplant. Early recognition of corneal allograft rejection and aggressive treatment may improve the survival of the corneal graft. Furthermore, patients who undergo corneal transplantation should be maintained under close ophthalmic surveillance and patients should be informed to report immediately whenever symptoms of corneal graft rejection occur. The mainstay of therapy is topical corticosteroids. In severe cases, periocular, intravenous, and oral corticosteroids therapy can be rendered. New therapeutic modalities such as cyclosporine, tacrolimus, daclizumab, mycophenolate mofetil, leflunomide, rapamycin, and others may prove to be of help in the prevention and treatment of corneal graft rejection. Early recognition of corneal graft rejection and prompt treatment are mandatory for the successful survival of the corneal allograft.

Residual stress characterization of steel TIG welds by neutron diffraction and by residual magnetic stray field mappings

Science.gov (United States)

Stegemann, Robert; Cabeza, Sandra; Lyamkin, Viktor; Bruno, Giovanni; Pittner, Andreas; Wimpory, Robert; Boin, Mirko; Kreutzbruck, Marc

2017-03-01

The residual stress distribution of tungsten inert gas welded S235JRC+C plates was determined by means of neutron diffraction (ND). Large longitudinal residual stresses with maxima around 600 MPa were found. With these results as reference, the evaluation of residual stress with high spatial resolution GMR (giant magneto resistance) sensors was discussed. The experiments performed indicate a correlation between changes in residual stresses (ND) and the normal component of local residual magnetic stray fields (GMR). Spatial variations in the magnetic field strength perpendicular to the welds are in the order of the magnetic field of the earth.

Endothelial cell chimerism associated with graft rejection after human lung transplantation.

OpenAIRE

Ratajczak , Philippe; Murata , Hideyuki; Meignin , Véronique; Groussard , Odile; Fournier , Michel; Socié , Gérard; Mal , Hervé; Janin , Anne

2008-01-01

International audience; Endotheliitis is a major sign of graft rejection. Recipient-derived endothelial cells found in two series of liver and kidney transplants were related to graft rejection. Here, we assessed the presence and the number of chimeric endothelial cells in lung transplants, and their relation with graft rejection. In six males grafted with female lungs out of 193 lung transplantations, endothelial chimerism was studied by combined XY-fluorescent in situ hybridization with CD3...

CALDER: Cryogenic light detectors for background-free searches

Energy Technology Data Exchange (ETDEWEB)

Cardani, L. [Dipartimento di Fisica - Sapienza Università di Roma, Roma - Italy and Physics Department, Princeton University, Princeton, NJ (United States); Bellini, F.; Casali, N.; Coppolecchia, A.; Cosmelli, C.; Cruciani, A.; Vignati, M. [Dipartimento di Fisica - Sapienza Università di Roma and INFN - Sezione di Roma, Roma - Italy (Italy); Castellano, M. G. [Istituto di Fotonica e Nanotecnologie - CNR, Roma - Italy (Italy); Colantoni, I. [Dipartimento di Fisica - Sapienza Università di Roma (Italy); Di Domizio, S. [Dipartimento di Fisica, Università di Genova, Genova - Italy and INFN Sezione di Genova, Genova - Italy (Italy); Tomei, C. [INFN - Sezione di Roma, Roma - Italy (Italy)

2015-08-17

The development of background-free detectors is essential for experiments searching for rare events. Bolometers, that are among the most competitive devices for the study of neutrino-less double beta decay (0νDBD) and Dark Matter interactions, suffer from the absence of techniques that allow to identify the nature of the interacting particles. This limit can be overcome by coupling the bolometer to an independent device for the measurement of the light emitted by interactions, as the combined read-out of the bolometric and light signals allows to identify and reject particles different from those of interest. CUORE, the most advanced bolometric experiment for 0νDBD searches, could disentangle the electrons produced by 0νDBD from the dangerous background due to α particles, by measuring the (tiny) Cherenkov light emitted by electrons and not by α’s. LUCIFER, a project based on ZnSe scintillating bolometers for the study of {sup 82}Se 0νDBD, would be competitive also in the search of Dark Matter interactions if equipped with light detectors that allow to distinguish and reject the background due to electrons and γ’s. These advances require cryogenic detectors characterized by noise lower than 20 eV, large active area, wide temperature range of operation, high radio-purity and ease in fabricating hundreds of channels. The CALDER collaboration aims to develop such detectors by exploiting the superb energy resolution and natural multiplexed read-out provided by Kinetic Inductance Detectors.

Line-up member similarity influences the effectiveness of a salient rejection option for eyewitnesses

OpenAIRE

Bruer, Kaila C.; Fitzgerald, Ryan J.; Therrien, Natalie M.; Price, Heather L.

2015-01-01

Visually salient line-up rejection options have not been systematically studied with adult eyewitnesses. We explored the impact of using a non-verbal, salient rejection option on adults' identification accuracy for line-ups containing low- or high-similarity fillers. The non-verbal, salient rejection option had minimal impact on accuracy in low-similarity line-ups, but in high-similarity line-ups its inclusion increased correct rejections for target-absent line-ups as well as incorrect reject...

Analysis of Turbine Load Rejection for APR1400 using SPACE

Energy Technology Data Exchange (ETDEWEB)

Kim, Sang Jin; Park, Chan Eok; Choi, Jong Ho; Lee, Gyu Cheon [KEPCO Engineering and Construction Co. Ltd., Deajeon (Korea, Republic of)

2016-10-15

Turbine Load Rejection event is one of the Performance Related Design Basis Event (PRDBE) that can be stabilized using plant control systems without any safety system actuation. The initiation of the event is turbine load rejection from 100% to 5% in 0.019 seconds. The NSSS control systems of APR1400 is composed of the Power Control System (PCS) and the Process-Component Control System (P-CCS). The PCS includes Reactor Regulating System (RRS), Reactor Power Cutback System (RPCS) and Digital Rod Control System (DRCS). The P-CCS includes the Pressurizer Pressure Control System (PPCS), the Pressurizer Level Control System (PLCS), the Feedwater Control System (FWCS) and the Steam Bypass Control System (SBCS). Turbine load rejection results in the increase of secondary pressure due to sudden blocking of steam flow to turbine. Then the Reactor Coolant System (RCS) cooling through steam generators is decreased rapidly and the RCS temperature will be increased. Turbine load rejection is a typical event to test NSSS control systems since it requires the automatic response of all major NSSS control systems. It is shown that the NSSS control systems of APR1400 have the capability to stabilize the plant without any safety system actuation for turbine load rejection event. This analysis results show that SPACE code has the capability to analyze the turbine load rejection event. However, further validation is necessary for other PRDBEs such as Two Main Feedwater Pumps Trip, Turbine Load Step Change and Turbine Load Ramp Down (5%/min) to verify the capability of SPACE for the full range of performance analyses.

Analysis of Turbine Load Rejection for APR1400 using SPACE

International Nuclear Information System (INIS)

Kim, Sang Jin; Park, Chan Eok; Choi, Jong Ho; Lee, Gyu Cheon

2016-01-01

Turbine Load Rejection event is one of the Performance Related Design Basis Event (PRDBE) that can be stabilized using plant control systems without any safety system actuation. The initiation of the event is turbine load rejection from 100% to 5% in 0.019 seconds. The NSSS control systems of APR1400 is composed of the Power Control System (PCS) and the Process-Component Control System (P-CCS). The PCS includes Reactor Regulating System (RRS), Reactor Power Cutback System (RPCS) and Digital Rod Control System (DRCS). The P-CCS includes the Pressurizer Pressure Control System (PPCS), the Pressurizer Level Control System (PLCS), the Feedwater Control System (FWCS) and the Steam Bypass Control System (SBCS). Turbine load rejection results in the increase of secondary pressure due to sudden blocking of steam flow to turbine. Then the Reactor Coolant System (RCS) cooling through steam generators is decreased rapidly and the RCS temperature will be increased. Turbine load rejection is a typical event to test NSSS control systems since it requires the automatic response of all major NSSS control systems. It is shown that the NSSS control systems of APR1400 have the capability to stabilize the plant without any safety system actuation for turbine load rejection event. This analysis results show that SPACE code has the capability to analyze the turbine load rejection event. However, further validation is necessary for other PRDBEs such as Two Main Feedwater Pumps Trip, Turbine Load Step Change and Turbine Load Ramp Down (5%/min) to verify the capability of SPACE for the full range of performance analyses

Source-Sink Estimates of Genetic Introgression Show Influence of Hatchery Strays on Wild Chum Salmon Populations in Prince William Sound, Alaska

OpenAIRE

Jasper, James R.; Habicht, Christopher; Moffitt, Steve; Brenner, Rich; Marsh, Jennifer; Lewis, Bert; Creelman Fox, Elisabeth; Grauvogel, Zac; Rogers Olive, Serena D.; Grant, W. Stewart

2013-01-01

The extent to which stray, hatchery-reared salmon affect wild populations is much debated. Although experiments show that artificial breeding and culture influence the genetics of hatchery salmon, little is known about the interaction between hatchery and wild salmon in a natural setting. Here, we estimated historical and contemporary genetic population structures of chum salmon (Oncorhynchus keta) in Prince William Sound (PWS), Alaska, with 135 single nucleotide polymorphism (SNP) markers. H...

Perception of Parental Acceptance and Rejection among Swedish University Students.

Science.gov (United States)

Kitahara, Michio

1987-01-01

Results of administering the Parental Acceptance-Rejection and Personality Assessment Questionnaires to 71 Swedish university students showed significant relationships between various forms of parental rejection in childhood and negative personality assessment of the self as an adult. Females showed more dependence and emotional instability than…

EEG asymmetry in borderline personality disorder and depression following rejection.

Science.gov (United States)

Beeney, Joseph E; Levy, Kenneth N; Gatzke-Kopp, Lisa M; Hallquist, Michael N

2014-04-01

Borderline personality disorder (BPD) and major depressive disorder (MDD) share numerous features, including dysphoric affect, irritability, suicidality, and a heightened sensitivity to perceived interpersonal rejection. However, these disorders are associated with divergent profiles of reactivity to rejection: Individuals with MDD are more likely to respond with withdrawal and isolation, and those with BPD appear to respond with increased approach behaviors and greater hostility. Potential mechanisms underlying these divergent patterns of response have not been elaborated. The goal of the present study was to assess whether prefrontal cortical asymmetry is associated with these behavioral profiles. EEG alpha activity was recorded at baseline and after individuals with BPD, MDD and healthy controls (HCs) participated in a rejection task. Although no differences were found at baseline, results demonstrated that following rejection, individuals with BPD showed greater left cortical activation, consistent with approach motivation, whereas those with MDD showed greater right cortical activation, consistent with withdrawal motivation. HCs evidenced a more balanced cortical profile, as hypothesized. Although BPD and MDD are highly comorbid, are easily confused, and are phenomenologically similar in a number of ways, individuals with these two disorders respond in very different ways to perceived rejection. PsycINFO Database Record (c) 2014 APA, all rights reserved

Design of an ultra-thin near-eye display with geometrical waveguide and freeform optics.

Science.gov (United States)

Cheng, Dewen; Wang, Yongtian; Xu, Chen; Song, Weitao; Jin, Guofan

2014-08-25

Small thickness and light weight are two important requirements for a see-through near-eye display which are achieved in this paper by using two advanced technologies: geometrical waveguide and freeform optics. A major problem associated with the geometrical waveguide is the stray light which can severely degrade the display quality. The causes and solutions to this problem are thoroughly studied. A mathematical model of the waveguide is established and a non-sequential ray tracing algorithm is developed, which enable us to carefully examine the stray light of the planar waveguide and explore a global searching method to find an optimum design with the least amount of stray light. A projection optics using freeform surfaces on a wedge shaped prism is also designed. The near-eye display integrating the projection optics and the waveguide has a field of view of 28°, an exit pupil diameter of 9.6mm and an exit pupil distance of 20mm. In our final design, the proportion of the stray light energy over the image output energy of the waveguide is reduced to 2%, the modulation transfer function values across the entire field of the eyepiece are above 0.5 at 30 line pairs/mm (lps/mm). A proof-of-concept prototype of the proposed geometrical waveguide near-eye display is developed and demonstrated.

[B-type natriuretic peptide assessment in the diagnosis of rejection after pediatric heart transplant].

Science.gov (United States)

Sylos, Cristina de; Azeka, Estela; Kajita, Luis; Benvenutti, Luis; Strunz, Célia Cassaro; Branco, Klébia Castello; Riso, Arlindo Almeida; Tanamati, Carla; Jatene, Marcelo; Barbero-Marcial, Miguel

2009-03-01

Rejection is one of the major causes of mortality following pediatric heart transplant. B-type natriuretic peptide (BNP) has been studied as a method for the diagnosis of acute rejection, especially in adult patients undergoing heart transplant. To correlate serum BNP levels with acute rejection as diagnosed by endomyocardial biopsy in patients of the pediatric heart transplant group. A total of 50 BNP samples were collected from 33 children in the postoperative period of heart transplant, and data on age, gender, skin color, blood group, immune panel, follow-up time after transplant, functional class, immunosuppressive regimen used and number of rejections were analyzed. Thirty three children with median age of 10.13 years were analyzed; of these, 54% were females and 78% were Caucasians. BNP levels were determined at a mean time from transplant of 4.25 years. Nine episodes of rejection were diagnosed in eight patients (27%) by means of endomyocardial biopsy; of these, three were grade 3A, five were grade 2, and one had humoral rejection. At the moment of biopsy, most patients were asymptomatic. The mean serum BNP level was 77.18 pg/ml, with 144.22 pg/ml in the group with rejection and 62.46 pg/ml in the group without rejection, with p = 0.02. Asymptomatic children can present acute rejection in the postoperative period of heart transplant. Serum BNP levels show a statistically significant difference in the group with rejection and thus can be an additional method in the diagnosis of cardiac rejection.

Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice

International Nuclear Information System (INIS)

Bix, M.; Nanshih Liao; Raulet, D.; Zijlstra, M.; Loring, J.; Jaenisch, R.

1991-01-01

Irradiated MHC-heterozygous mice often reject bone marrow cells transplanted from one of the homozygous parental strains, a phenomenon ('hybrid resistance') that appears to violate the laws of transplantation. Rejection of parental and allogeneic marrow cells also differs from conventional T cell-mediated rejection mechanisms as it is effected by NK1.1 + cells. To account for the unusual specificity of bone marrow rejection, it has been proposed that NK1.1 + cells destroy marrow cells that fail to express the full complement of self MHC class I (MHC-I) molecules. We show here that NK1.1 + cells in normal mice reject haemopoietic transplants from mice that are deficient for normal cell-surface MHC-I expression because of a targeted mutation in the β 2 -microglobulin gene. These findings demonstrate that deficient expression of MHC-I molecules renders marrow cells susceptible to rejection. (author)

Social exclusion in middle childhood: rejection events, slow-wave neural activity, and ostracism distress.

Science.gov (United States)

Crowley, Michael J; Wu, Jia; Molfese, Peter J; Mayes, Linda C

2010-01-01

This study examined neural activity with event-related potentials (ERPs) in middle childhood during a computer-simulated ball-toss game, Cyberball. After experiencing fair play initially, children were ultimately excluded by the other players. We focused specifically on “not my turn” events within fair play and rejection events within social exclusion. Dense-array ERPs revealed that rejection events are perceived rapidly. Condition differences (“not my turn” vs. rejection) were evident in a posterior ERP peaking at 420 ms consistent, with a larger P3 effect for rejection events indicating that in middle childhood rejection events are differentiated in <500 ms. Condition differences were evident for slow-wave activity (500-900 ms) in the medial frontal cortical region and the posterior occipital-parietal region, with rejection events more negative frontally and more positive posteriorly. Distress from the rejection experience was associated with a more negative frontal slow wave and a larger late positive slow wave, but only for rejection events. Source modeling with Geosouce software suggested that slow-wave neural activity in cortical regions previously identified in functional imaging studies of ostracism, including subgenual cortex, ventral anterior cingulate cortex, and insula, was greater for rejection events vs. “not my turn” events. © 2010 Psychology Press

Modeling of RO/NF membrane rejections of PhACs and organic compounds: a statistical analysis

Directory of Open Access Journals (Sweden)

G. Amy

2008-07-01

Full Text Available Rejections of pharmaceutical compounds (Ibuprofen, Diclofenac, Clofibric acid, Naproxen, Primidone, Phenacetin and organic compounds (Dichloroacetic acid, Trichloroacetic acid, Chloroform, Bromoform, Trichloroethene, Perchloroethene, Carbontetrachloride, Carbontetrabromide by NF (Filmtec, Saehan and RO (Filmtec, Saehan, Toray, Koch membranes were studied. Chloroform presented the lowest rejection due to small molar volume, equivalent width and length. Diclofenac and Primidone showed high rejections related to high molar volume and length. Dichloroacetic acid and Trichloroacetic acid presented good rejections caused by charge exclusion instead of steric hindrance mechanism influencing rejection. Bromoform and Trichloroethene showed low rejections due to small length and equivalent width. Carbontetrabromide, Perchloroethene and Carbontetrachloride with higher equivalent width than BF and TCE presented better rejections. A qualitative analysis of variables using Principal Component Analysis was successfully implemented for reduction of physical-chemical compound properties that influence membrane rejection of PhACs and organic compounds. Properties such as dipole moment, molar volume, hydrophobicity/hydrophilicity, molecular length and equivalent width were found to be important descriptors for simulation of membrane rejection. For membranes used in the experiments, we may conclude that charge repulsion was an important mechanism of rejection for ionic compounds. After analysis with Multiple Linear Regression, we also may conclude that membrane rejection of neutral compounds was well predicted by molar volume, length, equivalent width, hydrophobicity/hydrophilicity and dipole moment. Molecular weight was a poor descriptor variable for rejection modelling. We were able to provide acceptable statistical significance for important results.

A model of acute renal allograft rejection in outbred Yorkshire piglets.

Science.gov (United States)

Lassiter, Randi; Wang, Youli; Fang, Xuexiu; Winn, Matt; Ghaffari, Arina; Ho, Chak-Sum; Helman, Sandra; Jajosky, Ryan; Kleven, Daniel; Stanley Nahman, N; Merchen, Todd D

2017-06-01

Pigs represent a desirable animal model for the study of rejection in kidney transplantation with inbred Yucatan miniature swine (YMS) the most commonly studied strain due to well defined swine leukocyte antigen (SLA) genotypes. However, limitations to YMS may include cost and availability. Outbred Yorkshire pigs are widely available and significantly cheaper than YMS. Recent advances in SLA genotyping have allowed its application to outbred strains. On this basis, we theorized that Yorkshire pigs would be a viable alternative to YMS for the study of rejection in kidney transplantation. To address this question, we performed auto (Auto) and allotransplants (Allo) in 24 Yorkshire pigs, and assessed SLA genotypes and acute rejection after 72h. At sacrifice, and when compared to autotransplants, allotransplants had significant elevations in serum creatinine (8.4±1.3 vs 2.8±2.0mg/dL for Allo vs autotransplants, respectively) and BUN (61±9 vs 19.2±15mg/dL for Allo vs autotransplants, respectively). Warm ischemia times between the two groups did not differ (24±2.3 vs 26.4±1.4min for Auto vs Allo, respectively). There were 16 distinct SLA haplotypes identified from pigs undergoing allotransplantion, no matched donor-recipient pairs, and all allografts demonstrated rejection. Type IIA cellular rejection (Banff) was the most common. One allograft demonstrated hyperacute rejection due a blood group incompatibility. Histologically, the expression of regulatory Tcells and dendritic cells was increased in allografts. These data suggest that Yorkshire pigs may be a useful model for the study of acute rejection in experimental kidney transplantation. Copyright © 2017. Published by Elsevier B.V.

Soluble CD30 and HLA antibodies as potential risk factors for kidney transplant rejection.

Science.gov (United States)

Slavcev, Antonij; Lácha, Jiri; Honsová, Eva; Sajdlová, Helena; Lodererová, Alena; Vitko, Stefan; Skibová, Jelena; Striz, Ilja

2005-06-01

Recent literary data suggest that high pre- and post-transplant serum levels of the soluble CD30 (sCD30) molecule may be a risk factor for acute rejection and worse prognosis of the transplanted kidney. The aim of our study was to correlate the concentrations of sCD30 and the presence of HLA antibodies as defined by flow cytometry and ELISA with the clinical course and graft prognosis after transplantation. One hundred and seventeen kidney transplant patients were included into the study. The incidence of rejection episodes, graft function and graft survival for up to 1 year post-transplant were evaluated. Soluble CD30 levels before transplantation were virtually the same in patients who experienced rejection and in non-rejecting patients. In both patient groups, a significant decrease of sCD30 was detected 2 weeks after transplantation (104.4 U/ml before vs. 37.0 U/ml post-transplant, P sCD30 between rejecting and non-rejecting patients. Patients without rejection had lower sCD30 values (31.2 U/ml post-transplant) compared to patients who experienced rejection episodes (62.9 U/ml), P antigens and elevated concentrations of sCD30 shortly after transplantation were associated with increased risk for acute rejection in the first post-transplant year. Measurement of soluble CD30 after transplantation, taken into consideration with the presence of HLA class II antibodies, might be helpful for evaluating the potential risk for acute rejection.

Application of the Neganov-Luke effect to low-threshold light detectors

International Nuclear Information System (INIS)

Stark, M.; Boslau, O.; Feilitzsch, F.v.; Goldstrass, P.; Jochum, J.; Kemmer, J.; Potzel, W.; Rau, W.

2005-01-01

Simultaneous measurement of a temperature signal and scintillation light of a CaWO 4 crystal can be used for background rejection in cryogenic dark matter experiments. In our case the light is measured with a cryogenic detector that consists of a silicon absorber with a superconducting phase transition thermometer. Due to the Neganov-Luke effect the thermal signal is enhanced when a voltage is applied to the silicon absorber. First results with the application of this effect to our low-threshold light detectors will be discussed in this paper

Labor market position after a rejection of a disability pension application: a register-based cohort study.

Science.gov (United States)

Laaksonen, Mikko; Gould, Raija; Liukko, Jyri

2017-08-17

To study labor market positions of rejected disability pension applicants and to examine which characteristics predict ending up in these positions after the rejection. Nationwide Finnish register data was used to describe employment, unemployment and disability pension trajectories of rejected applicants (n = 5740) from four years before to four years after the rejection. Demographic, occupational and health-related determinants of labor market position after the rejection were examined among those employed and not employed at the time of the rejection. The proportion of the employed steeply decreased and that of unemployed increased before the rejection of a disability pension application. Four years after the rejection, 30% of the rejected applicants were employed, 24% were unemployed and 30% received disability pension. Employment at the time of the rejection, younger age, shorter unemployment history, public sector employment and milder work disability increased future employment. Manual work, public sector employment and previous long-term unemployment predicted future unemployment. Apart from higher age, associations with receiving disability pension were relatively weak. For many rejected disability pension applicants return to work is challenging. Special efforts should be targeted to support the remaining work ability and to promote employment opportunities of the rejected applicants. Implications for Rehabilitation Employment, unemployment and receiving disability pension were equally common labor market positions four years after the rejection. Rejected DP applicants with unemployment history need special efforts to increase their employability. As a disability pension application, even if rejected, clearly indicates some degree of work ability problems, rehabilitation should be targeted at this time point to support employment.

Kin Rejection: Social Signals, Neural Response and Perceived Distress During Social Exclusion

Science.gov (United States)

Sreekrishnan, Anirudh; Herrera, Tania A.; Wu, Jia; Borelli, Jessica L.; White, Lars O.; Rutherford, Helena J. V.; Mayes, Linda C.; Crowley, Michael J.

2014-01-01

Across species, kin bond together to promote survival. We sought to understand the dyadic effect of exclusion by kin (as opposed to non-kin strangers) on brain activity of the mother and her child and their subjective distress. To this end, we probed mother-child relationships with a computerized ball-toss game Cyberball. When excluded by one another, rather than by a stranger, both mothers and children exhibited a significantly pronounced frontal P2. Moreover, upon kin-rejection versus stranger-rejection, both mothers and children showed incremented left frontal positive slow waves for rejection events. Children reported more distress upon exclusion than their own mothers. Similar to past work, relatively augmented negative frontal slow wave activity predicted greater self-reported ostracism distress. This effect, generalized to the P2, was limited to mother or child- rejection by kin, with comparable magnitude of effect across kin identity (mothers vs. children). For both mothers and children, the frontal P2 peak was significantly pronounced for kin-rejection versus stranger rejection. Taken together, our results document the rapid categorization of social signals as kin-relevant and the specificity of early and late neural markers for predicting felt ostracism. PMID:24909389

Sociocultural Influence and Appearance-Based Rejection Sensitivity among College Students

Science.gov (United States)

Park, Lora E.; DiRaddo, Ann Marie; Calogero, Rachel M.

2009-01-01

The present research examined the influence of parents, peers, and the media in predicting college students' Appearance-based Rejection Sensitivity (Appearance-RS)--the degree to which individuals anxiously expect to be rejected based on their physical appearance. Given that women are socialized to be more appearance-focused than men, women were…

The Impact of an Electronic Ordering System on Blood Bank Specimen Rejection Rates.

Science.gov (United States)

Forest, Stefanie K; Shirazi, Maryam; Wu-Gall, Charlotte; Stotler, Brie A

2017-01-01

To evaluate the impact that an electronic ordering system has on the rate of rejection of blood type and screen testing samples and the impact on the number of ABO blood-type discrepancies over a 4-year period. An electronic ordering system was implemented in May 2011. Rejection rates along with reasons for rejection were tracked between January 2010 and December 2013. A total of 40,104 blood samples were received during this period, of which 706 (1.8%) were rejected for the following reasons: 382 (54.0%) unsigned samples, 235 (33.0%) mislabeled samples, 57 (8.0%) unsigned requisitions, 18 (2.5%) incorrect tubes, and 14 (1.9%) ABO discrepancies. Of the samples, 2.5% were rejected in the year prior to implementing the electronic ordering system compared with 1.2% in the year following implementation ( P  blood sample rejection. © American Society for Clinical Pathology, 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

Peripheral blood transcriptome sequencing reveals rejection-relevant genes in long-term heart transplantation.

Science.gov (United States)

Chen, Yan; Zhang, Haibo; Xiao, Xue; Jia, Yixin; Wu, Weili; Liu, Licheng; Jiang, Jun; Zhu, Baoli; Meng, Xu; Chen, Weijun

2013-10-03

Peripheral blood-based gene expression patterns have been investigated as biomarkers to monitor the immune system and rule out rejection after heart transplantation. Recent advances in the high-throughput deep sequencing (HTS) technologies provide new leads in transcriptome analysis. By performing Solexa/Illumina's digital gene expression (DGE) profiling, we analyzed gene expression profiles of PBMCs from 6 quiescent (grade 0) and 6 rejection (grade 2R&3R) heart transplant recipients at more than 6 months after transplantation. Subsequently, quantitative real-time polymerase chain reaction (qRT-PCR) was carried out in an independent validation cohort of 47 individuals from three rejection groups (ISHLT, grade 0,1R, 2R&3R). Through DGE sequencing and qPCR validation, 10 genes were identified as informative genes for detection of cardiac transplant rejection. A further clustering analysis showed that the 10 genes were not only effective for distinguishing patients with acute cardiac allograft rejection, but also informative for discriminating patients with renal allograft rejection based on both blood and biopsy samples. Moreover, PPI network analysis revealed that the 10 genes were connected to each other within a short interaction distance. We proposed a 10-gene signature for heart transplant patients at high-risk of developing severe rejection, which was found to be effective as well in other organ transplant. Moreover, we supposed that these genes function systematically as biomarkers in long-time allograft rejection. Further validation in broad transplant population would be required before the non-invasive biomarkers can be generally utilized to predict the risk of transplant rejection. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Resilience and rejection sensitivity mediate long-term outcomes of parental divorce.

Science.gov (United States)

Schaan, Violetta K; Vögele, Claus

2016-11-01

Increasing divorce rates leave more and more children to deal with the separation of their parents. Recent research suggests that children of divorced parents more often experience psychological and physical symptoms than children of non-divorced parents. The processes that mediate the relationship between parental divorce and ill-health, however, are still elusive. This study investigated the mediating role of psychological factors such as resilience and rejection sensitivity on the long-term consequences of parental divorce in young adults. One hundred and ninety-nine participants (mean age 22.3 years) completed an online survey, including measures of mental health, childhood trauma, resilience, and rejection sensitivity. Participants with divorced parents (33 %) reported increased levels of psychological symptoms, childhood trauma, rejection sensitivity, and lower levels of resilience. The association between parental divorce and mental health was fully mediated by resilience, rejection sensitivity, and childhood trauma. The mediation model explained up to 44 % of the total variance in mental health symptoms. Resilience and rejection sensitivity are crucial factors for successful coping with the experience of parental separation. Prevention programs that help to boost children's resilience might help to reduce the long-term effects of parental divorce on their attachment style (e.g., rejection sensitivity), thereby improving their mental health on the long run. Furthermore, the results call for parental awareness and counseling to target and reduce the observed increased level of childhood trauma. Limitations concern the cross-sectional and retrospective design of the study.

Role of Soluble ST2 as a Marker for Rejection after Heart Transplant.

Science.gov (United States)

Lee, Ga Yeon; Choi, Jin-Oh; Ju, Eun-Seon; Lee, Yoo-Jung; Jeon, Eun-Seok

2016-11-01

Endomyocardial biopsy is obligatory during the first year after heart transplant (HTx) for the surveillance of acute rejection. Previous attempts using cardiac biomarkers for the detection of rejection failed to show enough evidence to substitute endomyocardial biopsy. Therefore, this study sought the possibility of using soluble ST2 (sST2), a novel cardiovascular marker, as a surrogate marker for acute allograft rejection after HTx. A total of 494 blood samples acquired at the time of endomyocardial biopsy were analyzed in 67 HTx cases from September 2006 to August 2014. Significant rejection was defined as International Society of Heart and Lung Transplant (ISHLT) score ≥2R and humoral rejection accompanied by hemodynamic instability. Twenty cases of HTx with 22 blood samples showed significant rejection in endomyocardial biopsy at 4.0 (2.0-9.0) months after HTx. The level of sST2 showed positive correlation with cardiac troponin I, and N-terminal pro-B-type natriuretic peptide (all prejection) (p=0.003). However, when we studied within-subject effects of sST2 using a mixed model, the sST2 level according to the predefined time point was not different according to the presence of significant rejection (p for interaction=0.94). Although sST2 is known as a promising predictor for cardiovascular events, its role in HTx patients to predict acute allograft rejection seems to be limited.

Prevalence of Toxoplasma gondii antibodies and intestinal parasites in stray cats from Nigde, Turkey

Directory of Open Access Journals (Sweden)

Bengi Dündar

2010-01-01

Full Text Available The prevalence of antibodies to Toxoplasma gondii was investigated by the Sabin-Feldman Dye test (SFDT in 72 stray cats from Nigde, Turkey. A total of 55 (76.4% of the analysed sera had antibodies to T. gondii. The seropositivity of T. gondii was 77.1% in male and 75.7% in female cats (P>0.05. Faeces of these cats were also examined by zinc sulphate flotation method for the presence of parasite oocysts and eggs of other parasites. Two protozoan parasites were identified as Isospora spp. (12.5% and Eimeria spp. (4.1% in cats. Toxoplasma gondii oocysts were not found in any faecal samples analysed. Two parasitic helminth species were observed: Toxocara cati (15.2% and Toxascaris leonina (20.8%. These common ascarids were recorded for the first time in cats from Nigde.

Evaluation of renal allograft rejection by Doppler sonography and MR imaging

International Nuclear Information System (INIS)

Steinberg, H.V.; Nelson, R.C.; Murphy, F.B.; Baumgartner, B.R.; Bourke, E.; Delaney, V.B.; Whelchel, J.B.; Bernardino, M.E.

1986-01-01

The authors prospectively studies the efficacy of Doppler sonography and MR imaging in evaluating renal allografts, with specific attention to transplant rejection. Based on study findings, we were unable to make a statement with respect to the appearance or accuracy of diagnosing cyclosporin toxicity or acute tubular necrosis by either modality due to concomitant rejection in the few patients so afflicted. Moreover, the ability to predict and diagnose the presence or absence of allograft rejection was not affected by different serum creatinine values. Most important, however, Doppler sonography was shown to be superior to MR imaging in evaluating for allograft rejection, as evidenced by its higher sensitivity (100% vs. 71%), specificity (88% vs. 75%), and accuracy (96% vs. 73%). Thus, because of its low cost and ease of accessibility, Doppler sonography should become the primary modality for renal transplant screening

Gene-Based Multiclass Cancer Diagnosis with Class-Selective Rejections

Science.gov (United States)

Jrad, Nisrine; Grall-Maës, Edith; Beauseroy, Pierre

2009-01-01

Supervised learning of microarray data is receiving much attention in recent years. Multiclass cancer diagnosis, based on selected gene profiles, are used as adjunct of clinical diagnosis. However, supervised diagnosis may hinder patient care, add expense or confound a result. To avoid this misleading, a multiclass cancer diagnosis with class-selective rejection is proposed. It rejects some patients from one, some, or all classes in order to ensure a higher reliability while reducing time and expense costs. Moreover, this classifier takes into account asymmetric penalties dependant on each class and on each wrong or partially correct decision. It is based on ν-1-SVM coupled with its regularization path and minimizes a general loss function defined in the class-selective rejection scheme. The state of art multiclass algorithms can be considered as a particular case of the proposed algorithm where the number of decisions is given by the classes and the loss function is defined by the Bayesian risk. Two experiments are carried out in the Bayesian and the class selective rejection frameworks. Five genes selected datasets are used to assess the performance of the proposed method. Results are discussed and accuracies are compared with those computed by the Naive Bayes, Nearest Neighbor, Linear Perceptron, Multilayer Perceptron, and Support Vector Machines classifiers. PMID:19584932

Hybrid pulse pile-up rejection system as applied to Rutherford backscattering

International Nuclear Information System (INIS)

Boie, R.A.; Wildnauer, K.R.

1977-01-01

The problems of pulse on pulse pile-up and noise limited pile-up rejectors are considered in detail for Rutherford backscattering spectra. The forms of these spectra allow the distortions from pile-up and the residual pile-up after rejection to be understood via a simple model. Extended calculations allow us to predict the effects quite accurately. A new pile-up rejection system is described. The ''linear'' rejection method is implemented with peak stretchers and advantageously combined with an event counting rejector to provide a versatile high performance system

Crosslinked cellulose thin film composite nanofiltration membranes with zero salt rejection

KAUST Repository

Puspasari, Tiara; Neelakanda, Pradeep; Peinemann, Klaus-Viktor

2015-01-01

advantage for a complete desalination as the existing commercial nanofiltration membranes typically exhibit NaCl rejection in the range of 30–60%. Membranes with zero NaCl rejection are required for recovery and purification applications in food, chemical

Research on rejection performance of reverse osmosis to nickel in simulated radioactive wastewater

International Nuclear Information System (INIS)

Kong Jinsong; Wang Xiaowei

2013-01-01

In order to reveal the rejection performance of the reverse osmosis applied in the radioactive wastewater treatment, treatment experiments were carried out on a pilot reverse osmosis equipment using wastewater containing nickel nuclide. Results showed that the rejection ratio of reverse osmosis to nickel was almost not affected by the operation pressure and the ratio of reclaiming, and had no direct relation with the salt rejection ratio. The ratio of nickel rejection reached 95% in the experiment condition and could meet the requirement on the disposal of radioactive wastewater produced by nuclear powered installations. (authors)

Research on rejection performance of reverse osmosis to cobalt in simulated radioactive wastewater

International Nuclear Information System (INIS)

Kong Jinsong; Tian Yanjie

2012-01-01

In order to reveal the rejection performance of the reverse osmosis applied in the radioactive wastewater treatment, treatment experiments were carried out on a pilot reverse osmosis equipment using wastewater containing cobalt nuclide. Results showed that the rejection ratio of reverse osmosis to cobalt was almost not affected by the operation pressure and the ratio of reclaiming, and had no direct relation with the salt rejection ratio. The ratio of cobalt rejection reached 90% in the experiment condition and could meet the requirement on the disposal of radioactive wastewater produced by nuclear powered installations. (authors)

Effectiveness of a social relations intervention program for aggressive and nonaggressive, rejected children.

Science.gov (United States)

Lochman, J E; Coie, J D; Underwood, M K; Terry, R

1993-12-01

A sample of 52 Black aggressive, rejected and nonaggressive, rejected children were randomly assigned to receive a social relations intervention or to be in a nonintervention control group. The school-based intervention for fourth-grade children focused on positive social skill training and cognitive-behavioral strategies to promote deliberate, nonimpulsive problem solving. At both the post-treatment and the 1-year follow-up assessments, the social relations intervention was found to be effective only with the aggressive, rejected children. Implications for the importance of assessing subtypes of rejected children are discussed.

18 CFR 35.5 - Rejection of material submitted for filing.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Rejection of material submitted for filing. 35.5 Section 35.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... that fails to comply with this Part may be rejected by the Director of the Office of Energy Market...

Prostanoids modulate inflammation and alloimmune responses during graft rejection

Directory of Open Access Journals (Sweden)

P.N. Rocha

2005-12-01

Full Text Available Acute rejection of a transplanted organ is characterized by intense inflammation within the graft. Yet, for many years transplant researchers have overlooked the role of classic mediators of inflammation such as prostaglandins and thromboxane (prostanoids in alloimmune responses. It has been demonstrated that local production of prostanoids within the allograft is increased during an episode of acute rejection and that these molecules are able to interfere with graft function by modulating vascular tone, capillary permeability, and platelet aggregation. Experimental data also suggest that prostanoids may participate in alloimmune responses by directly modulating T lymphocyte and antigen-presenting cell function. In the present paper, we provide a brief overview of the alloimmune response, of prostanoid biology, and discuss the available evidence for the role of prostaglandin E2 and thromboxane A2 in graft rejection.

Self-esteem moderates neuroendocrine and psychological responses to interpersonal rejection.

Science.gov (United States)

Ford, Máire B; Collins, Nancy L

2010-03-01

In this study, the authors investigated self-esteem as a moderator of psychological and physiological responses to interpersonal rejection and tested an integrative model detailing the mechanisms by which self-esteem may influence cognitive, affective, and physiological responses. Seventy-eight participants experienced an ambiguous interpersonal rejection (or no rejection) from an opposite sex partner in the context of an online dating interaction. Salivary cortisol was assessed at 5 times, and self-reported cognitive and affective responses were assessed. Compared with those with high self-esteem, individuals with low self-esteem responded to rejection by appraising themselves more negatively, making more self-blaming attributions, exhibiting greater cortisol reactivity, and derogating the rejector. Path analysis indicated that the link between low self-esteem and increased cortisol reactivity was mediated by self-blame attributions; cortisol reactivity, in turn, mediated the link between low self-esteem and increased partner derogation. Discussion centers on the role of self-esteem as part of a broader psychobiological system for regulating and responding to social threat and on implications for health outcomes.

Comparison of renal allograft (AG) biopsy diagnosis and temporal quantitation of Tc-99m sulfur colloid (SC) in clinically suspected AG rejection

International Nuclear Information System (INIS)

George, E.A.; Brown, W.N.; Carney, K.; Naidu, R.G.; Palmer, D.C.

1984-01-01

The purpose of this study was to evaluate the diagnostic efficacy of temporal quantitation of SC compared to tissue diagnosis of AG needle biopsy (Bx). The principal clinical criteria for patient selection were sequential or persistent reduction (at least 40-50%) of AG function as determined by serial serum creatinine levels. Thirty-four AG recipients were examined with SC and subsequent AG Bx in 37 instances. %SC AG accumulation and bone marrow extraction were interpreted in view of the significant sequential of persistent reduction of Ag function. Each AG Bx was collected from multiple needle aspirates and processed for light microscopy and immunoflorescent staining. Bx and SC exam were evaluated for acute rejection (AR), chronic rejection (CR) or other, non-rejection pathology. Acute tissue changes superimposed on chronic were regarded as AR. Acute tissue changes and % SC AG accumulation in the rejection range were graded as mild, moderate and marked. In AR there was 28/28 agreement of Bx and SC diagnosis; of which 7/28 were superimposed on CR. In Cr Bx and SC agreed in 3/7 instances, in 3/7 SC Dx was AR and in 1/7 SC exam was normal. Sensitivity and specificity of the SC diagnosis in this series was 100% and 63% for AR, 43% and 100% for CR and 97% and 100% in all instances of rejection. Bx and SC grading of AR agreed in 64%. In conclusion, temporal quantitation of SC demonstrated overall good correlation with AG Bx diagnosis in this series. The poor sensitivity of 43% of SC in Cr and only 64% correlation in grading AR may be due to inherent Bx sampling and SC data analysis error

Acute Hepatic Allograft Rejection in Pediatric Recipients: Independent Factors

OpenAIRE

Dehghani, S. M.; Shahramian, I.; Afshari, M.; Bahmanyar, M.; Ataollahi, M.; Sargazi, A.

2017-01-01

Background: Acute cellular rejection (ACR) has a reversible effect on graft and its survival. Objective: To evaluate the relation between ACR and clinical factors in recipients of liver transplant allografts. Methods: 47 consecutive liver recipients were retrospectively studied. Their data were extracted from records and analyzed. Results: 38 (81%) of the 47 recipients experienced ACR during a 24-month follow-up. The rate of rejection was associated with none of the studied factors—recipient’...

Reject analysis: A comparison of radiographer and radiologist perceptions of image quality

International Nuclear Information System (INIS)

Mount, J.

2016-01-01

This study explores the potential differences in perceptions of image quality between radiographers and radiologists in a large UK hospital and the subsequent impact this has on image rejection. Image rejection, while sometimes necessary, often leads to an increased radiation dose to the patient due to the need to repeat. Moreover, this translates into increased waiting times, departmental costs, and lower patient satisfaction. Adopting a mixed methods approach, this paper first seeks to quantify the differences in radiographer and radiologist perceptions and second establish the underlying causes of such differences through a quantitative and qualitative investigation respectively. Using a standardized psychometric scale of a GP lateral knee, the study reveals significant differences in the perceptions of quality and rejection rates between radiographers and radiologists driven by a conflict in the evaluation criteria used. The study has significant implications for improving departmental performance and proposes a potential solution for reducing reject rates and image repeats. - Highlights: • Significant differences are found to exist in perceptions of image quality. • Differences in perceptions of image quality directly influence reject rates. • Radiographers judge images on technical criteria. • Radiologists judge images on diagnostic criteria. • Results suggest better communication could reduce reject rates.

A small asparagine-rich protein required for S-allele-specific pollen rejection in Nicotiana.

Science.gov (United States)

McClure, B; Mou, B; Canevascini, S; Bernatzky, R

1999-11-09

Although S-locus RNases (S-RNases) determine the specificity of pollen rejection in self-incompatible (SI) solanaceous plants, they alone are not sufficient to cause S-allele-specific pollen rejection. To identify non-S-RNase sequences that are required for pollen rejection, a Nicotiana alata cDNA library was screened by differential hybridization. One clone, designated HT, hybridized strongly to RNA from N. alata styles but not to RNA from Nicotiana plumbaginifolia, a species known to lack one or more factors necessary for S-allele-specific pollen rejection. Sequence analysis revealed a 101-residue ORF including a putative secretion signal and an asparagine-rich domain near the C terminus. RNA blot analysis showed that the HT-transcript accumulates in the stigma and style before anthesis. The timing of HT-expression lags slightly behind S(C10)-RNase in SI N. alata S(C10)S(C10) and is well correlated with the onset of S-allele-specific pollen rejection in the style. An antisense-HT construct was prepared to test for a role in pollen rejection. Transformed (N. plumbaginifolia x SI N. alata S(C10)S(C10)) hybrids with reduced levels of HT-protein continued to express S(C10)-RNase but failed to reject S(C10)-pollen. Control hybrids expressing both S(C10)-RNase and HT-protein showed a normal S-allele-specific pollen rejection response. We conclude that HT-protein is directly implicated in pollen rejection.

Utilization Of Diets Containing Cashew-Nut Reject Meal By Weaner ...

African Journals Online (AJOL)

A trial was conducted to assess the performance and digestibility of weaner pigs fed diets containing cashew nut reject meal (CNM). A control diet was formulated without cashew nut reject meal while two other diets were also formulated to contain either 50g or 100g/kg diet. The CNM replaced soybean meal in the control ...

Image processing methods for noise reduction in the TJ-II Thomson Scattering diagnostic

Energy Technology Data Exchange (ETDEWEB)

Dormido-Canto, S., E-mail: sebas@dia.uned.es [Departamento de Informatica y Automatica, UNED, Madrid 28040 (Spain); Farias, G. [Pontificia Universidad Catolica de Valparaiso, Valparaiso (Chile); Vega, J.; Pastor, I. [Asociacion EURATOM/CIEMAT para Fusion, Madrid 28040 (Spain)

2012-12-15

Highlights: Black-Right-Pointing-Pointer We describe an approach in order to reduce or mitigate the stray-light on the images and show the exceptional results. Black-Right-Pointing-Pointer We analyze the parameters to take account in the proposed process. Black-Right-Pointing-Pointer We report a simplified exampled in order to explain the proposed process. - Abstract: The Thomsom Scattering diagnostic of the TJ-II stellarator provides temperature and density profiles. The CCD camera acquires images corrupted with noise that, in some cases, can produce unreliable profiles. The main source of noise is the so-called stray-light. In this paper we describe an approach that allows mitigation of the effects that stray-light has on the images: extraction regions with connected-components. In addition, the robustness and effectiveness of the noise reduction technique is validated in two ways: (1) supervised classification and (2) comparison of electron temperature profiles.

The role of conspiracist ideation and worldviews in predicting rejection of science.

Directory of Open Access Journals (Sweden)

Stephan Lewandowsky

Full Text Available Among American Conservatives, but not Liberals, trust in science has been declining since the 1970's. Climate science has become particularly polarized, with Conservatives being more likely than Liberals to reject the notion that greenhouse gas emissions are warming the globe. Conversely, opposition to genetically-modified (GM foods and vaccinations is often ascribed to the political Left although reliable data are lacking. There are also growing indications that rejection of science is suffused by conspiracist ideation, that is the general tendency to endorse conspiracy theories including the specific beliefs that inconvenient scientific findings constitute a "hoax."We conducted a propensity weighted internet-panel survey of the U.S. population and show that conservatism and free-market worldview strongly predict rejection of climate science, in contrast to their weaker and opposing effects on acceptance of vaccinations. The two worldview variables do not predict opposition to GM. Conspiracist ideation, by contrast, predicts rejection of all three scientific propositions, albeit to greatly varying extents. Greater endorsement of a diverse set of conspiracy theories predicts opposition to GM foods, vaccinations, and climate science.Free-market worldviews are an important predictor of the rejection of scientific findings that have potential regulatory implications, such as climate science, but not necessarily of other scientific issues. Conspiracist ideation, by contrast, is associated with the rejection of all scientific propositions tested. We highlight the manifold cognitive reasons why conspiracist ideation would stand in opposition to the scientific method. The involvement of conspiracist ideation in the rejection of science has implications for science communicators.

Prediction of acute cardiac rejection by changes in left ventricular volumes

International Nuclear Information System (INIS)

Novitzky, D.; Cooper, D.K.; Boniaszczuk, J.

1988-01-01

Sixteen patients underwent heart transplantation (11 orthotopic, five heterotopic). Monitoring for acute rejection was by both endomyocardial biopsy (EMB) and multigated equilibrium blood pool scanning with technetium 99m-labelled red blood cells. From the scans information was obtained on left ventricular volumes (stroke, end-diastolic, and end-systolic), ejection fraction, and heart rate. Studies (208) were made in the 16 patients. There was a highly significant correlation between the reduction in stroke volume and end-diastolic volume (and a less significant correlation in end-systolic volume) and increasing acute rejection seen on EMB. Heart rate and ejection fraction did not correlate with the development of acute rejection. Correlation of a combination of changes in stroke volume and end-diastolic volume with EMB showed a sensitivity of 85% and a specificity of 96%. Radionuclide scanning is therefore a useful noninvasive tool for monitoring acute rejection

Ultrafiltration of protein solutions; the role of protein association in rejection and osmotic pressure

NARCIS (Netherlands)

van den Berg, G.B.; Hanemaaijer, J.H.; Smolders, C.A.

1987-01-01

The monomer-dimer equilibrium of the protein β-lactoglobulin under neutral conditions appears to influence the rejection and the osmotic pressure build-up, both phenomena closely related to ultrafiltration. Rejection measurements indicate different rejections for the β-lactoglobulin monomers and

Reward, addiction, and emotion regulation systems associated with rejection in love.

Science.gov (United States)

Fisher, Helen E; Brown, Lucy L; Aron, Arthur; Strong, Greg; Mashek, Debra

2010-07-01

Romantic rejection causes a profound sense of loss and negative affect. It can induce clinical depression and in extreme cases lead to suicide and/or homicide. To begin to identify the neural systems associated with this natural loss state, we used functional magnetic resonance imaging to study 10 women and 5 men who had recently been rejected by a partner but reported they were still intensely "in love." Participants alternately viewed a photograph of their rejecting beloved and a photograph of a familiar, individual, interspersed with a distraction-attention task. Their responses while looking at their rejecter included love, despair, good, and bad memories, and wondering why this happened. Activation specific to the image of the beloved occurred in areas associated with gains and losses, craving and emotion regulation and included the ventral tegmental area (VTA) bilaterally, ventral striatum, medial and lateral orbitofrontal/prefrontal cortex, and cingulate gyrus. Compared with data from happily-in-love individuals, the regional VTA activation suggests that mesolimbic reward/survival systems are involved in romantic passion regardless of whether one is happily or unhappily in love. Forebrain activations associated with motivational relevance, gain/loss, cocaine craving, addiction, and emotion regulation suggest that higher-order systems subject to experience and learning also may mediate the rejection reaction. The results show activation of reward systems, previously identified by monetary stimuli, in a natural, endogenous, negative emotion state. Activation of areas involved in cocaine addiction may help explain the obsessive behaviors associated with rejection in love.

the vision of divine light in saint gregory palamas's theology

African Journals Online (AJOL)

in Romania. 2. THE RECEPTION OF SAINT GREGORY PALAMAS'S. THEOLOGY IN THE WEST. In the West, the reception of Saint Gregory Palamas's theology, as it is known, was rather a negative one. His doctrine of divine light was rejected, because it postulated the possibility of seeing God with corporeal eyes. (Lossky ...

Parental alignments and rejection: an empirical study of alienation in children of divorce.

Science.gov (United States)

Johnston, Janet R

2003-01-01

This study of family relationships after divorce examined the frequency and extent of child-parent alignments and correlates of children's rejection of a parent, these being basic components of the controversial idea of "parental alienation syndrome." The sample consisted of 215 children from the family courts and general community two to three years after parental separation. The findings indicate that children's attitudes toward their parents range from positive to negative, with relatively few being extremely aligned or rejecting. Rejection of a parent has multiple determinants, with both the aligned and rejected parents contributing to the problem, in addition to vulnerabilities within children themselves.

Perceived parental acceptance/rejection, some family characteristics and conduct disorder in adolescents.

Science.gov (United States)

Kostić, Jelena; Nešić, Milkica; Stanković, Miodrag; Zikić, Olivera

2014-10-01

Conduct disorder is characterized by repetitive and persistent presence of dissocial, aggressive and defiant behavioral patterns, thus represents important public issue with comprehensive and far-reaching consequences both for the individual and society. The aim of this study was to investigate the differences in sociodemographic family characteristics and the prominence of parental acceptance/rejection dimensions in groups of adolescents with and without conduct disorder, as well as to examine the connection between parental acceptance/rejection dimensions and externalizing symptoms in the group of adolescents with conduct disorder. This research was conducted on 134 adolescents, aged 15 to 18, using the Parental Acceptance/Rejection Questionnaire (PARQ child), Youth Self-Report (YSR), and a questionnaire constructed for the purpose of this survey. The results showed that the number of adolescents with conduct disorder coming from divorced families was significandy higher than from complete families (44.8% vs 13.4%, respectively; p disorders compared to the controls (31.3% vs 8.9%; respectively; p = 0.001). The perceived rejection dimension and the total index of maternal acceptance/rejection were significantly higher in adolescents with conduct disorder than in those with no such disorder (132.30 ± 38.05 vs 93.91 ± 26.29 respectively; p conduct disorder and severe perceived maternal and paternal rejection showed a significantly higher average score on the subscale of externalizing symptoms (14.55 ± 4.45 and 13.27 + 5.05) compared to adolescents with conduct disorder and lower total index of parental acceptance/rejection (8.32 ± 5.05 and 8.28 ± 5.08). The results suggest that adolescents with conduct disorder perceive their parents as more rejecting and less warm and supportive compared to adolescents without conduct disorder. The perception of significant and severe parental rejection was associated with a significantly higher averaged score on the subscale

CARDIAC TRANSPLANT REJECTION AND NON-INVASIVE COMON CAROTID ARTERY WALL FUNCTIONAL INDICES

Directory of Open Access Journals (Sweden)

A. O. Shevchenko

2015-01-01

Full Text Available Allograft rejection would entail an increase in certain blood biomarkers and active substances derived from activated inflammatory cells which could influence entire vascular endothelial function and deteriorate arterial wall stiffness. We propose that carotid wall functional indices measured with non-invasive ultrasound could we valuable markers of the subclinical cardiac allograft rejection. Aim. Our goal was to analyze the clinical utility of functional common carotid wall (CCW variables measured with high-resolution Doppler ultrasound as a non-invasive screening tool for allograft rejection in cardiac transplant patients (pts. Methods. One hundred and seventy one pts included 93 cardiac recipients, 30 dilated cardiomyopathy waiting list pts, and 48 stable coronary artery disease (SCAD pts without decompensated heart failure were included. Along with resistive index (Ri, pulsative index (Pi, and CCW intima-media thickness (IMT, CCW rigidity index (iRIG was estimated using empirical equation. Non-invasive evaluation was performed in cardiac transplant recipients prior the endomyo- cardial biopsy. Results. Neither of Ri, Pi, or CCW IMT were different in studied subgroups. iRIG was signifi- cantly lower in SCAD pts when compared to the dilated cardiomyopathy subgroup. The later had similar values with cardiac transplant recipients without rejection. Antibody-mediated and cellular rejection were found in 22 (23.7% and 17 (18.3% cardiac recipients, respectively. Mean iRIG in pts without rejection was significantly lower in comparison to antibody-mediated rejection and cell-mediated (5514.7 ± 2404.0 vs 11856.1 ± 6643.5 and 16071.9 ± 10029.1 cm/sec2, respectively, p = 0.001. Area under ROC for iRIG was 0.90 ± 0.03 units2. Analysis showed that iRIG values above estimated treshold 7172 cm/sec2 suggested relative risk of any type of rejection 17.7 (95%CI = 6.3–49.9 sensitivity 80.5%, specificity – 81.1%, negative predictive value – 84

Total lymphoid irradiation in the treatment of early or recurrent heart transplant rejection

International Nuclear Information System (INIS)

Salter, Susan P.; Salter, Merle M.; Kirklin, James K.; Bourge, Robert C.; Naftel, David C.

1995-01-01

Purpose: Recurrent acute cardiac allograft rejection is an important cause of repeat hospitalization and a major mode of mortality, particularly during the 6 months immediately following transplant. Total lymphoid irradiation (TLI) has been shown experimentally to induce a state of partial tolerance when administered prior to transplantation. Anecdotal reports of clinical experience have also suggested efficacy of TLI in treatment of recurrent cardiac rejection. The purpose of this study is to evaluate the safety and efficacy of TLI for treatment of early or recurrent heart transplant rejection. Materials and Methods: Between January 1990 and June 1992, 49 patients postallograft cardiac transplant were given courses of TLI for treatment of early or recurrent rejection after conventional therapy with Methylprednisolone, antithymocyte globulin, OKT3, and methotrexate. Two patients failed to complete their therapy and were not evaluated. Two other patients received a second TLI course, making a total of 49 courses delivered. Indications for TLI were early rejection (n = 5), recurrent rejection (n = 38), and recurrent rejection with vasculitis (n = 6). The dose goal of the TLI protocol was 8 Gy in 10 fractions given twice weekly. Three separate fields were used to encompass all major lymph node-bearing areas. The actual mean dose was 7 Gy (range 2.4-8.4 Gy), and the duration of treatment was 8 to 106 days. These variations were secondary to leukopenia or thrombocytopenia. Results: The mean posttransplant follow-up is 15 ± 1.2 months (maximum 27 months). Among patients initiating TLI within 1 month posttransplant (n = 15), the rejection frequency decreased from 1.83 episodes/patient/month pre-TLI to 0.13 episodes/patient/month post-TLI (p < 0.0001). For those who began TLI 1-3 months after transplant (n = 21), rejection decreased from 1.43 to 0.10 episodes/patient/month (p < 0.0001). When TLI was started more than 3 months posttransplant (n = 11), the pre-TLI and post

Evaluation of posttransplantation soluble CD30 for diagnosis of acute renal allograft rejection.

Science.gov (United States)

Pelzl, Steffen; Opelz, Gerhard; Daniel, Volker; Wiesel, Manfred; Süsal, Caner

2003-02-15

Posttransplantation measurement of soluble CD30 (sCD30) may be useful for identifying kidney graft recipients at risk of impending graft rejection in the early posttransplantation period. We measured plasma sCD30 levels and evaluated the levels in relation to the diagnosis of rejection. Receiver operating characteristic curves demonstrated that on posttransplantation days 3 to 5, sCD30 allowed a differentiation of recipients who subsequently developed acute allograft rejection (n=25) from recipients with an uncomplicated course (n=20, Pacute tubular necrosis in the absence of rejection (n=11, P=0.001) (area under the receiver operating characteristic curve 0.85, specificity 91%, sensitivity 72%). sCD30 measured on posttransplantation days 3 to 5 offers a noninvasive means for differentiating patients with impending acute allograft rejection from patients with an uncomplicated course or with acute tubular necrosis.

Exceptional ion rejection ability of directional solvent for non-membrane desalination

Energy Technology Data Exchange (ETDEWEB)

Rish, Daniel [Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana 46556 (United States); Department of Civil Engineering, University of Notre Dame, Notre Dame, Indiana 46556 (United States); Luo, Shirui; Kurtz, Brien [Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana 46556 (United States); Luo, Tengfei, E-mail: tluo@nd.edu [Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana 46556 (United States); Center for Sustainable Energy at Notre Dame, University of Notre Dame, Notre Dame, Indiana 46556 (United States)

2014-01-13

The recently demonstrated directional solvent extraction (DSE) is promising for very low temperature, membrane-free water desalination. In this paper, we combine atomistic simulations and experimental validation to demonstrate that the currently used directional solvent, decanoic acid, can reject all major salt ions in seawater, with very high rejection rates. The salinities of the DSE recovered water show that ion rejection rates are ∼98%–99%—similar to those of the best reverse osmosis membranes. Our test also shows that the DSE process can desalt seawater to produce fresh water that meets drinking water standards.

Exceptional ion rejection ability of directional solvent for non-membrane desalination

International Nuclear Information System (INIS)

Rish, Daniel; Luo, Shirui; Kurtz, Brien; Luo, Tengfei

2014-01-01

The recently demonstrated directional solvent extraction (DSE) is promising for very low temperature, membrane-free water desalination. In this paper, we combine atomistic simulations and experimental validation to demonstrate that the currently used directional solvent, decanoic acid, can reject all major salt ions in seawater, with very high rejection rates. The salinities of the DSE recovered water show that ion rejection rates are ∼98%–99%—similar to those of the best reverse osmosis membranes. Our test also shows that the DSE process can desalt seawater to produce fresh water that meets drinking water standards

Rejection Sensitivity Mediates the Relationship between Social Anxiety and Body Dysmorphic Concerns

Science.gov (United States)

Fang, Angela; Asnaani, Anu; Gutner, Cassidy; Cook, Courtney; Wilhelm, Sabine; Hofmann, Stefan G.

2011-01-01

The goal of this study was to examine the role of rejection sensitivity in the relationship between social anxiety and body dysmorphic concerns. To test our hypothesis that rejection sensitivity mediates the link between social anxiety and body dysmorphic concerns, we administered self-report questionnaires to 209 student volunteers. Consistent with our prediction, rejection sensitivity partially mediated the relationship between social anxiety symptoms and body dysmorphic concerns. The implications of the overlap between these constructs are discussed. PMID:21741203

The Role of Tissue-Resident Donor T Cells in Rejection of Clinical Face Transplants

Science.gov (United States)

2017-10-01

cells contribute to VCA rejection, and that pathogenic T cells (both donor and recipient-derived) are detectable in blood during rejection to serve as...AWARD NUMBER: W81XWH-16-1-0760 TITLE: The role of tissue-resident donor T cells in rejection of clinical face transplants PRINCIPAL...AND SUBTITLE The role of tissue-resident donor T cells in rejection of clinical face transplants 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-16-1

Does contrast between eggshell ground and spot coloration affect egg rejection?

Science.gov (United States)

Dainson, Miri; Hauber, Mark E; López, Analía V; Grim, Tomáš; Hanley, Daniel

2017-08-01

Obligate avian brood parasitic species impose the costs of incubating foreign eggs and raising young upon their unrelated hosts. The most common host defence is the rejection of parasitic eggs from the nest. Both egg colours and spot patterns influence egg rejection decisions in many host species, yet no studies have explicitly examined the role of variation in spot coloration. We studied the American robin Turdus migratorius, a blue-green unspotted egg-laying host of the brown-headed cowbird Molothrus ater, a brood parasite that lays non-mimetic spotted eggs. We examined host responses to model eggs with variable spot coloration against a constant robin-mimetic ground colour to identify patterns of rejection associated with perceived contrast between spot and ground colours. By using avian visual modelling, we found that robins were more likely to reject eggs whose spots had greater chromatic (hue) but not achromatic (brightness) contrast. Therefore, egg rejection decision rules in the American robin may depend on the colour contrast between parasite eggshell spot and host ground coloration. Our study also suggests that egg recognition in relation to spot coloration, like ground colour recognition, is tuned to the natural variation of avian eggshell spot colours but not to unnatural spot colours.

Lymphocele: a possible relationship with acute cellular rejection in kidney transplantation

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Marco Aurélio Silva Lipay

1999-11-01

Full Text Available CONTEXT: The incidence of lymphocele after renal transplantation varies between 0.6 and 18% of cases, and many factors have been associated to its etiology. Cellular rejection of the kidney allograft has been described as a possible causal factor of lymphocele. OBJECTIVE: To analyze the possible relationship between lymphocele and acute cellular rejection. DESIGN: A retrospective study. SETTING: A referral hospital center. SAMPLE: 170 patients submitted to kidney transplantation from March 1992 to January 1997. A standard technique for renal transplantation was used. RESULTS: Of the 19 patients that developed lymphocele, 16 presented at least one episode of acute cell rejection (84%, and were treated with methylprednisolone. The relation between lymphocele and rejection was statistically significant (p = 0.04. Treatment of lymphocele consisted of peritoneal marsupialization in 3 patients (15.3%, percutaneous drainage in 7 (36.8%, laparascopic marsupialization in 2 (10.5%, and conservative treatment in 7 patients (36.8%. Evolution was favorable in 15 patients (78.9%, 1 patient (5.3% died due to a cause unrelated to lymphocele, and 3 (15.8% lost the graft due to immunological factors. The average follow-up period was 24.5 months. CONCLUSION: The high incidence of acute cell rejection in patients with lymphocele suggests a possible causal relationship between both conditions.

Ex Vivo Model of Human Penile Transplantation and Rejection: Implications for Erectile Tissue Physiology.

Science.gov (United States)

Sopko, Nikolai A; Matsui, Hotaka; Lough, Denver M; Miller, Devin; Harris, Kelly; Kates, Max; Liu, Xiaopu; Billups, Kevin; Redett, Richard; Burnett, Arthur L; Brandacher, Gerald; Bivalacqua, Trinity J

2017-04-01

Penile transplantation is a potential treatment option for severe penile tissue loss. Models of human penile rejection are lacking. Evaluate effects of rejection and immunosuppression on cavernous tissue using a novel ex vivo mixed lymphocyte reaction (MLR) model. Cavernous tissue and peripheral blood mononuclear cells (PBMCs) from 10 patients undergoing penile prosthesis operations and PBMCs from a healthy volunteer were obtained. Ex vivo MLRs were prepared by culturing cavernous tissue for 48h in media alone, in media with autologous PBMCs, or in media with allogenic PBMCs to simulate control, autotransplant, and allogenic transplant conditions with or without 1μM cyclosporine A (CsA) or 20nM tacrolimus (FK506) treatment. Rejection was characterized by PBMC flow cytometry and gene expression transplant array. Cavernous tissues were evaluated by histomorphology and myography to assess contraction and relaxation. Data were analyzed using two-way analysis of variance and unpaired Student t test. Flow cytometry and tissue array demonstrated allogenic PBMC activation consistent with rejection. Rejection impaired cavernous tissue physiology and was associated with cellular infiltration and apoptosis. CsA prevented rejection but did not improve tissue relaxation. CsA treatment impaired relaxation in tissues cultured without PBMCs compared with media and FK506. Study limitations included the use of penile tissue with erectile dysfunction and lack of cross-matching data. This model could be used to investigate the effects of penile rejection and immunosuppression. Additional studies are needed to optimize immunosuppression to prevent rejection and maximize corporal tissue physiology. This report describes a novel ex vivo model of human penile transplantation rejection. Tissue rejection impaired erectile tissue physiology. This report suggests that cyclosporin A might hinder corporal physiology and that other immunosuppressant agents, such as FK506, might be better suited

Investigation of structure in the modular light pipe component for LED automotive lamp

Science.gov (United States)

Chen, Hsi-Chao; Zhou, Yang; Huang, Chien-Sheng; Jhong, Wan-Ling; Cheng, Bo-Wei; Jhang, Jhe-Ming

2014-09-01

Light-Emitting Diodes (LEDs) have the advantages of small length, long lifetime, fast response time (μs), low voltage, good mechanical properties and environmental protection. Furthermore, LEDs could replace the halogen lamps to avoid the mercury pollution and economize the use of energy. Therefore, the LEDs could instead of the traditional lamp in the future and became an important light source. The proposal of this study was to investigate the effects of the structure and length of the reflector component for a LED automotive lamp. The novel LED automotive lamp was assembled by several different modularization columnar. The optimized design of the different structure and the length to the reflector was simulated by software TracePro. The design result must met the vehicle regulation of United Nations Economic Commission for Europe (UNECE) such as ECE-R19 etc. The structure of the light pipe could be designed by two steps structure. Then constitute the proper structure and choose different power LED to meet the luminous intensity of the vehicle regulation. The simulation result shows the proper structure and length has the best total luminous flux and a high luminous efficiency for the system. Also, the stray light could meet the vehicle regulation of ECE R19. Finally, the experimental result of the selected structure and length of the light pipe could match the simulation result above 80%.

Problematic Social Situations for Peer-Rejected Students in the First Year of Elementary School

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Luis Jorge Martín-Antón

2016-12-01

Full Text Available This study examined the social situations that are problematic for peer-rejected students in the first year of elementary school. For this purpose, exploratory and confirmatory factor analyses were conducted on the Taxonomy of Problematic Social Situations for Children (TOPS, Dodge et al., 1985 in 169 rejected pupils, identified from a sample of 1457 first-grade students (ages 5-7 enrolled in 62 classrooms of elementary school. For each rejected student, another student of average sociometric status of the same gender was selected at random from the same classroom (naverage = 169. The model for the rejected students showed a good fit, and was also invariant in the group of average students. Four types of situations were identified in which rejected students have significantly more difficulties than average students. They are, in descending order: (a respect for authority and rules, (b being disadvantaged, (c prosocial and empathic behavior, and (d response to own success. Rejected boys have more problems in situations of prosociability and empathy than girls. The implications concerning the design of specific programs to prevent and reduce early childhood rejection in the classroom are discussed.

Heat Rejection from a Variable Conductance Heat Pipe Radiator Panel

Science.gov (United States)

Jaworske, D. A.; Gibson, M. A.; Hervol, D. S.

2012-01-01

A titanium-water heat pipe radiator having an innovative proprietary evaporator configuration was evaluated in a large vacuum chamber equipped with liquid nitrogen cooled cold walls. The radiator was manufactured by Advanced Cooling Technologies, Inc. (ACT), Lancaster, PA, and delivered as part of a Small Business Innovative Research effort. The radiator panel consisted of five titanium-water heat pipes operating as thermosyphons, sandwiched between two polymer matrix composite face sheets. The five variable conductance heat pipes were purposely charged with a small amount of non-condensable gas to control heat flow through the condenser. Heat rejection was evaluated over a wide range of inlet water temperature and flow conditions, and heat rejection was calculated in real-time utilizing a data acquisition system programmed with the Stefan-Boltzmann equation. Thermography through an infra-red transparent window identified heat flow across the panel. Under nominal operation, a maximum heat rejection value of over 2200 Watts was identified. The thermal vacuum evaluation of heat rejection provided critical information on understanding the radiator s performance, and in steady state and transient scenarios provided useful information for validating current thermal models in support of the Fission Power Systems Project.

Explaining the paradoxical rejection-aggression link: the mediating effects of hostile intent attributions, anger, and decreases in state self-esteem on peer rejection-induced aggression in youth

NARCIS (Netherlands)

Reijntjes, A.; Thomaes, S.; Kamphuis, J.H.; Bushman, B.J.; Orobio de Castro, B.; Telch, M.J.

2011-01-01

People are strongly motivated to feel accepted by others. Yet when faced with acute peer rejection they often aggress against the very peers they desire acceptance from, which may lead to further rejection. The present experiment tests three potential mediators of aggressive responses to acute peer

Explaining the paradoxical rejection-aggression link: The mediating effects of hostile intent attributions, anger, and decreases in state self-esteem on peer rejection-induced aggression in youth

NARCIS (Netherlands)

Reijntjes, A.H.A.; Thomaes, S.C.E.; Kamphuis, J.H.; Bushman, B. J.; Orobio de Castro, B.; Telch, M.J.

2011-01-01

People are strongly motivated to feel accepted by others. Yet when faced with acute peer rejection they often aggress against the very peers they desire acceptance from, which may lead to further rejection. The present experiment tests three potential mediators of aggressive responses to acute peer

CD16+ Monocytes and Skewed Macrophage Polarization toward M2 Type Hallmark Heart Transplant Acute Cellular Rejection.

Science.gov (United States)

van den Bosch, Thierry P P; Caliskan, Kadir; Kraaij, Marina D; Constantinescu, Alina A; Manintveld, Olivier C; Leenen, Pieter J M; von der Thüsen, Jan H; Clahsen-van Groningen, Marian C; Baan, Carla C; Rowshani, Ajda T

2017-01-01

During acute heart transplant rejection, infiltration of lymphocytes and monocytes is followed by endothelial injury and eventually myocardial fibrosis. To date, no information is available on monocyte-macrophage-related cellular shifts and their polarization status during rejection. Here, we aimed to define and correlate monocyte-macrophage endomyocardial tissue profiles obtained at rejection and time points prior to rejection, with corresponding serial blood samples in 25 heart transplant recipients experiencing acute cellular rejection. Additionally, 33 healthy individuals served as control. Using histology, immunohistochemistry, confocal laser scan microscopy, and digital imaging expression of CD14, CD16, CD56, CD68, CD80, and CD163 were explored to define monocyte and macrophage tissue profiles during rejection. Fibrosis was investigated using Sirius Red stainings of rejection, non-rejection, and 1-year biopsies. Expression of co-stimulatory and migration-related molecules on circulating monocytes, and production potential for pro- and anti-inflammatory cytokines were studied using flow cytometry. At tissue level, striking CD16+ monocyte infiltration was observed during rejection ( p  rejection compared to barely present CD68+CD80+ M1 macrophages. Rejection was associated with severe fibrosis in 1-year biopsies ( p  rejection status, decreased frequencies of circulating CD16+ monocytes were found in patients compared to healthy individuals. Rejection was reflected by significantly increased CD54 and HLA-DR expression on CD16+ monocytes with retained cytokine production potential. CD16+ monocytes and M2 macrophages hallmark the correlates of heart transplant acute cellular rejection on tissue level and seem to be associated with fibrosis in the long term.

Peer Rejection and Internalizing Behavior: The Mediating Role of Peer Victimization in Preschool.

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Metin Aslan, Özge

2018-05-23

The author examined the relationship among peer rejection, peer victimization, and internalizing behaviors. The author hypothesized that physical and relational victimization would have a different indirect effect on the relationship between peer rejection and internalizing behaviors. Participants were 94 preschool children (37 girls; average age 49.97 months) from two university preschools located in the northern part of the United States. The results indicated that internalizing behaviors predicted the mediating variables only regarding relational victimization. Relational victimization indirectly affected the association between peer rejection and internalizing behaviors. The study provides evidence of the mediating effect of victimization behaviors on the relationship among peer rejection, victimization, and internalizing behaviors.

PERTUMBUHAN TANAMAN JAGUNG (Zea mays, L. VARIETAS BISI-2 PADA PASIR REJECT DAN PASIR ASLI DI PANTAI TRISIK KULONPROGO (The Growth of Maize Crop (Zea mays L. BISI-2 Variety on Rejected and non Rejected Sand at Pantai Trisik Kulon Progo

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Diah Ekowati

2011-11-01

Full Text Available ABSTRAK Lahan pasir di pesisir Kabupaten Kulon Progo yang sekarang ditanami berbagai komoditi pertanian seperti cabe, semangka, jagung akan ditambang untuk diekstrak mineral besinya. Rencananya setelah diekstrak mineral besinya, pasir sisa (pasir reject akan dikembalikan sebagai material reklamasi untuk dapat ditanami kembali. Tujuan penelitian ini adalah untuk mengetahui pengaruh perbedaan media tanam berupa pasir reject dan pasir asli serta dosis pupuk kandang dan pupuk NPK pada pertumbuhan tanaman jagung (Zea mays L. varietas BISI-2 di Pantai Trisik Kulon Progo. Dosis pupuk yang diberikan ialah 0 Kg pupuk kandang dan 0 g NPK (kontrol; 0 Kg pupuk kandang dan 75 g NPK; 2,5 Kg pupuk kandang dan 0 g NPK; 1,25 Kg pupuk kandang dan 112,5 g NPK; 2,5 Kg pupuk kandang dan 75 g pupuk NPK; dan 3,75 Kg pupuk kandang dan 37,5 g NPK. Parameter yang diamati pada penelitian ini adalah tinggi tanaman, jumlah daun, berat kering tajuk, waktu berbunga, jumlah tongkol, berat tongkol, panjang tongkol, dan diameter tongkol. Data yang diperoleh diuji dengan analisis variansi (Anava dan uji lanjut dengan Duncan’s Multiple Range Test (DMRT. Hasil penelitian menunjukkan bahwa rerata tinggi, jumlah daun, berat kering tajuk, jumlah tongkol, berat tongkol, panjang tongkol dan diameter tongkol tanaman jagung pada pasir reject lebih tinggi daripada pasir asli sedangkan rerata waktu berbunga tanaman jagung pada pasir reject lebih lama daripada pasir asli. Selain itu, hasil penelitian menunjukkan bahwa pertumbuhan vegetatif tanaman jagung paling optimal diperoleh pada dosis 1,25 Kg pupuk kandang dan 112,5 g pupuk NPK sedangkan pertumbuhan generatif tanaman jagung paling optimal diperoleh pada dosis 3,75 Kg pupuk kandang dan 37,5 g pupuk NPK.   ABSTRACT Sand in the coastal District of Kulon Progo land which is now planted with various agricultural commodities such as pepper, watermelon, corn, will be mined to extract its iron minerals. In the mining plan, after the iron

Implementation and rejection of industrial steam system energy efficiency measures

International Nuclear Information System (INIS)

Therkelsen, Peter; McKane, Aimee

2013-01-01

Steam systems consume approximately one third of energy applied at US industrial facilities. To reduce energy consumption, steam system energy assessments have been conducted on a wide range of industry types over the course of 5 years through the Energy Savings Assessment (ESA) program administered by the US Department of Energy (US DOE). ESA energy assessments result in energy efficiency measure recommendations that are given potential energy and energy cost savings and potential implementation cost values. Saving and cost metrics that measure the impact recommended measures will have at facilities, described as percentages of facility baseline energy and energy cost, are developed from ESA data and used in analyses. Developed savings and cost metrics are examined along with implementation and rejection rates of recommended steam system energy efficiency measures. Based on analyses, implementation of steam system energy efficiency measures is driven primarily by cost metrics: payback period and measure implementation cost as a percentage of facility baseline energy cost (implementation cost percentage). Stated reasons for rejecting recommended measures are primarily based upon economic concerns. Additionally, implementation rates of measures are not only functions of savings and cost metrics, but time as well. - Highlights: ► We examine uptake/rejection of industrial steam system energy efficiency measures. ► We examine metrics that correspond to uptake/rejection of recommended measures. ► We examine barriers hindering steam system energy efficiency measure implementation. ► Uptake/rejection of steam measures is linked to potential cost metrics. ► Increased uptake of measures and uptake of more costly measures increases with time

Mutual best friendship involvement, best friends' rejection sensitivity, and psychological maladaptation.

Science.gov (United States)

Bowker, Julie C; Thomas, Katelyn K; Norman, Kelly E; Spencer, Sarah V

2011-05-01

Rejection sensitivity (RS) refers to the tendency to anxiously expect, readily perceive, and overreact to experiences of possible rejection. RS is a clear risk factor for psychological maladaptation during early adolescence. However, there is growing evidence of significant heterogeneity in the psychological correlates of RS. To investigate when RS poses the greatest psychological risk during early adolescence, this study examines mutual best friendship involvement (or lack thereof) and the best friends' RS as potential moderators of the associations between RS and psychological difficulties. Participants were 150 7th grade students (58 boys; M age = 13.05 years) who nominated their best friends, and reported on their RS, social anxiety, and self-esteem. Results from a series of hierarchical multiple regression analyses indicated that mutual best friendship involvement and best friends' RS were both significant moderators when fear of negative evaluation (a type of social anxiety) served as the dependent variable. The association between RS and fear of negative evaluation was stronger for adolescents without mutual best friends than adolescents with mutual best friends. In addition, the association between RS and fear of negative evaluation was the strongest for adolescents whose best friends were highly rejection sensitive (relative to adolescents whose best friends were moderately or low in RS). Findings highlight the importance of considering best friendships in studies of RS and strongly suggest that, although having mutual best friendships may be protective for rejection sensitive adolescents, having a rejection sensitive best friend may exacerbate difficulties. The significance of friends in the lives of rejection sensitive adolescents is discussed as well as possible applied implications of the findings and study limitations.

Immune function surveillance: association with rejection, infection and cardiac allograft vasculopathy.

Science.gov (United States)

Heikal, N M; Bader, F M; Martins, T B; Pavlov, I Y; Wilson, A R; Barakat, M; Stehlik, J; Kfoury, A G; Gilbert, E M; Delgado, J C; Hill, H R

2013-01-01

Rejection, cardiac allograft vasculopathy (CAV), and infection are significant causes of mortality in heart transplantation recipients. Assessing the immune status of a particular patient remains challenging. Although endomyocardial biopsy (EMB) and angiography are effective for the identification of rejection and CAV, respectively, these are expensive, invasive, and may have numerous complications. The aim of this study was to evaluate the immune function and assess its utility in predicting rejection, CAV, and infection in heart transplantation recipients. We prospectively obtained samples at the time of routine EMB and when clinically indicated for measurement of the ImmuKnow assay (IM), 12 cytokines and soluble CD30 (sCD30). EMB specimens were evaluated for acute cellular rejection, and antibody-mediated rejection (AMR). CAV was diagnosed by the development of angiographic coronary artery disease. Infectious episodes occurring during the next 30 days after testing were identified by the presence of positive bacterial or fungal cultures and/or viremia that prompted treatment with antimicrobials. We collected 162 samples from 56 cardiac transplant recipients. There were 31 infection episodes, 7 AMR, and 4 CAV cases. The average IM value was significantly lower during infection, (P = .04). Soluble CD30 concentrations showed significantly positive correlation with infection episodes, (P = .001). Significant positive correlation was observed between interleukin-5(IL-5) and AMR episodes (P = .008). Tumor necrosis factor-α and IL-8 showed significant positive correlation with CAV (P = .001). Immune function monitoring appears promising in predicting rejection, CAV, and infection in cardiac transplantation recipients. This approach may help in more individualized immunosuppression and it may also minimize unnecessary EMBs and cardiac angiographies. Published by Elsevier Inc.

Drugs in development for prophylaxis of rejection in kidney-transplant recipients

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Sanders ML

2015-08-01

Full Text Available Marion Lee Sanders,1 Anthony James Langone2 1Department of Medicine, Division of Nephrology and Hypertension, University of Iowa, Iowa City, IA, 2Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN, USA Abstract: Transplantation is the preferred treatment option for individuals with end-stage renal disease. Individuals who undergo transplantation must chronically be maintained on an immunosuppression regimen for rejection prophylaxis to help ensure graft survival. Current rejection prophylaxis consists of using a combination of calcineurin inhibitors, mTOR inhibitors, antimetabolite agents, and/or corticosteroids. These agents have collectively improved the short-term outcomes of renal transplantation, but improvements in late/chronic graft loss and recipient survival have lagged significantly behind challenging the field of transplantation to develop novel prophylactic agents. There have been several clinical trials conducted within the last 5 years in an attempt to bring such novel agents to the commercial market. These trials have resulted in the US Food and Drug Administration (FDA approval of extended-release tacrolimus, as well as belatacept, which has the potential to replace calcineurin inhibitors for rejection prophylaxis. Other trials have focused on the development of novel calcineurin inhibitors (voclosporin, costimulation blockade (ASKP1240 and alefacept, kinase inhibitors (tofacitinib and sotrastaurin, and inhibitors of leukocyte migration (efalizumab. While these later agents have not been FDA-approved for use in transplantation, they remain noteworthy, as these agents explore pathways not previously targeted for allograft-rejection prophylaxis. The purpose of this review was to consolidate available clinical trial data with regard to the recent developments in rejection prophylaxis in kidney transplantation. Keywords: rejection, prophylaxis, immunosuppression

EEG Asymmetry in Borderline Personality Disorder and Depression Following Rejection

OpenAIRE

Beeney, Joseph E.; Levy, Kenneth N.; Gatzke-Kopp, Lisa M.; Hallquist, Michael N.

2013-01-01

Borderline personality disorder (BPD) and major depressive disorder (MDD) share numerous features including dysphoric affect, irritability, suicidality, and a heightened sensitivity to perceived interpersonal rejection. However, these disorders are associated with divergent profiles of reactivity to rejection; individuals with MDD are more likely to respond with withdrawal and isolation, and those with BPD appear to respond with increased approach behaviors and greater hostility. Potential me...

A Pilot Study of Mesenchymal Stem Cell Therapy for Acute Liver Allograft Rejection

OpenAIRE

Shi, Ming; Liu, Zhenwen; Wang, Ying; Xu, Rounan; Sun, Yanling; Zhang, Min; Yu, Xi; Wang, Hongbo; Meng, Lingzhan; Su, Haibin; Jin, Lei; Wang, Fu‐Sheng

2017-01-01

Abstract Acute allograft rejection remains common after liver transplantation despite modern immunosuppressive agents. In addition, the long‐term side effects of these regimens, including opportunistic infections, are challenging. This study evaluated the safety and clinical feasibility of umbilical cord‐derived mesenchymal stem cell (UC‐MSC) therapy in liver transplant patients with acute graft rejection. Twenty‐seven liver allograft recipients with acute rejection were randomly assigned int...

A new rejection of moral expertise.

Science.gov (United States)

Cowley, Christopher

2005-01-01

There seem to be two clearly-defined camps in the debate over the problem of moral expertise. On the one hand are the "Professionals", who reject the possibility entirely, usually because of the intractable diversity of ethical beliefs. On the other hand are the "Ethicists", who criticise the Professionals for merely stipulating science as the most appropriate paradigm for discussions of expertise. While the subject matter and methodology of good ethical thinking is certainly different from that of good clinical thinking, they argue, this is no reason for rejecting the possibility of a distinctive kind of expertise in ethics, usually based on the idea of good justification. I want to argue that both are incorrect, partly because of the reasons given by one group against the other, but more importantly because both neglect what is most distinctive about ethics: that it is personal in a very specific way, without collapsing into relativism.

Marginality and Social Rejection in Amiri Baraka's Slave Ship

Directory of Open Access Journals (Sweden)

Hamid Hammad Abed

2016-11-01

Full Text Available Marginality and social rejection are the most influential matters exploited by Baraka to intentionally criticize the American society.  More often than not, these two matters have become the scenes of major or minor acts of humiliation and dehumanization that threaten to violate the ethical rules of living. This paper aims at investigating the impact of marginality and social rejection on a number of black characters in Baraka's Slave Ship who are brought to America to be sold as commodities. It is divided into two sections and conclusion. Section one deals with Amiri Baraka’s dramatic thought and experience of marginality within the American society. The textual analysis of Slave Ship is investigated in section two. The significance of the study lies in its textual exploration of the impact of marginality and social rejection in subverting the American dream of democracy, freedom, and equality in Baraka’s Slave Ship.

Scaled-model guidelines for formation-flying solar coronagraph missions.

Science.gov (United States)

Landini, Federico; Romoli, Marco; Baccani, Cristian; Focardi, Mauro; Pancrazzi, Maurizio; Galano, Damien; Kirschner, Volker

2016-02-15

Stray light suppression is the main concern in designing a solar coronagraph. The main contribution to the stray light for an externally occulted space-borne solar coronagraph is the light diffracted by the occulter and scattered by the optics. It is mandatory to carefully evaluate the diffraction generated by an external occulter and the impact that it has on the stray light signal on the focal plane. The scientific need for observations to cover a large portion of the heliosphere with an inner field of view as close as possible to the photospheric limb supports the ambition of launching formation-flying giant solar coronagraphs. Their dimension prevents the possibility of replicating the flight geometry in a clean laboratory environment, and the strong need for a scaled model is thus envisaged. The problem of scaling a coronagraph has already been faced for exoplanets, for a single point source on axis at infinity. We face the problem here by adopting an original approach and by introducing the scaling of the solar disk as an extended source.

Optimization of a photon rejecter to separate electronic noise in a photon-counting detector

International Nuclear Information System (INIS)

Cho, Hyo-Min; Choi, Yu-Na; Lee, Seung-Wan; Lee, Young-Jin; Ryu, Hyun-Ju; Kim, Hee-Joung

2012-01-01

Photon-counting-based X-ray imaging technology provides the capability to count individual photons and to characterize photon energies. The cadmium telluride (CdTe)-based photon-counting detector is limited in capability, however, under a high X-ray flux. A photon rejecter composed of aluminum, for example, can reduce this limitation by modulating the incident number of photons. In addition to this function, the optimal photon rejecter can separate electronic noise, which degrades image quality. The aim of this work was to optimize a photon rejecter for high-quality image acquisition by removing electronic noise from the actual pulse signal. The images and spectra were acquired using a micro-focus X-ray source with a CdTe-based photon-counting detector. We acquired data with various types of photon-rejecter materials composed of aluminum (Al) and iodine at three different tube voltages (50, 70, and 90 kVp). A phantom composed of high-atomic-number materials was imaged to evaluate the efficiency of the photon rejecter. Photon rejecters composed of 1-mm Al, 10-mm Al, and a combination of 10-mm Al and iodine provided optimum capability at 50, 70, and 90 kVp, respectively. Each optimal combination of photon-rejecter material and voltage effectively separated electronic noise from the actual pulse signal and gave the highest contrast-to-noise ratio for materials on the image. These optimized types of photon rejecters can effectively discriminate electronic noise and improve image quality at different tube voltages.

21 CFR 111.170 - What requirements apply to rejected components, packaging, and labels, and to rejected products...

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What requirements apply to rejected components... supplement? 111.170 Section 111.170 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN...

Rejection index for pressure tubes

International Nuclear Information System (INIS)

Mitchell, A.B.; Meneley, D.

1989-10-01

The objective of the present study was to establish a set of criteria (or Rejection Index) which could be used to decide whether a zirconium-2 1/2 w/o niobium pressure tube in a CANDU reactor should be removed from service due to in-service degradation. A critique of key issues associated with establishing a realistic rejection index was prepared. Areas of uncertainty in available information were identified and recommendations for further analysis and laboratory testing made. A Rejection Index based on the following limits has been recommended: 1) Limits related to design intent and normal operation: any garter spring must remain within the tolerance band specified for its design location; the annulus gas system must normally be operated in a circulating mode with a procedure in place for purging to prevent accumulation of deuterium. It must remain sensitive to leaks into any part of the systems; and pressure tube dimensions and distortions must be limited to maintain the fuel channels within the original design intent; 2) Limits related to defect tolerance: adequate time margins between occurrence of a leaking crack and unstable failure must be demonstrated for all fuel channels; long lap-type flaws are unacceptable; crack-like defects of any size are unacceptable; and score marks, frat marks and other defects with contoured profiles must fall below certain depth, length and stress intensity limits; and 3) Limits related to property degradation: at operating temperature each pressure tube must be demonstrated to have a critical length in excess of a stipulated value; the maximum equivalent hydrogen level in any pressure tube should not exceed a limit which should be defined taking into account the known history of that tube; the maximum equivalent hydrogen level in any rolled joint should not exceed a limit which is presently recommended as 200 ppm equivalent hydrogen; and the maximum diametral creep strain should be limited to less than 5%

Posttransplant soluble CD30 as a predictor of acute renal allograft rejection.

Science.gov (United States)

Kamali, Koosha; Abbasi, Mohammad Amin; Farokhi, Babak; Abbasi, Ata; Fallah, Parvane; Seifee, Mohammad Hasan; Ghadimi, Naime; Rezaie, Alireza R

2009-12-01

Recent results have indicated that high prerenal and postrenal transplant soluble CD30 levels may be associated with an increased acute rejection and graft loss. The aim of this study was to evaluate the feasibility of using serum sCD30 as a marker for predicting acute graft rejection. In this prospective study,we analyzed clinical data of 80 patients, whose pretransplant and posttransplant serum levels of sCD30 were detected by enzyme-linked immunoassay. Eight patients developed acute rejection, 7 patients showed delayed graft function, and 65 recipients experienced an uncomplicated course group. The patients were followed for 12 months, and there were no deaths. Preoperative sCD30 levels of 3 groups were 96.2 -/+ 32.5, 80.2 -/+ 28.3, and 76.8 -/+ 29.8 U/mL (P = .28). After transplant, a significant decrease in the sCD30 level was detected in 3 groups on day 14 posttransplant (P sCD30 levels of acute rejection group remained significantly higher than delayed graft function and nonrejecting patients (28.3 -/+ 5.2, 22.1 -/+ 3.2, and 19.8 -/+ 4.7 U/mL) (P = .02). Positive panel reactive antibody was not statistically different among groups (P = .05). Also, hemodialysis did not affect sCD30 levels (P = .05). Receiver operating characteristic curve demonstrated that the sCD30 level on day 14 posttransplant could discriminate patients who subsequently suffered acute allograft rejection (area under receiver operating characteristic curve, 0.95). According to receiver operating characteristic curve, 20 U/mL may be the optimal operational cutoff level to predict impending graft rejection (specificity 93.8%, sensitivity 83.3%). Measurement of the soluble CD30 level on day 14 after transplant might offer a noninvasive means for recognizing patients at risk of acute graft rejection during the early posttransplant period.

RNaseI from Escherichia coli cannot substitute for S-RNase in rejection of Nicotiana plumbaginifolia pollen.

Science.gov (United States)

Beecher, B; Murfett, J; McClure, B A

1998-03-01

Unilateral incompatibility often occurs between self-incompatible (SI) species and their self-compatible (SC) relatives. For example, SI Nicotiana alata rejects pollen from SC N. plumbaginifolia, but the reciprocal pollination is compatible. This interspecific pollen rejection system closely resembles intraspecific S-allele-specific pollen rejection. However, the two systems differ in degree of specificity. In SI, rejection is S-allele-specific, meaning that only a single S-RNase causes rejection of pollen with a specific S genotype. Rejection of N. plumbaginifolia pollen is less specific, occurring in response to almost any S-RNase. Here, we have tested whether a non-S-RNase can cause rejection of N. plumbaginifolia pollen. The Escherichia coli rna gene encoding RNAseI was engineered for expression in transgenic (N. plumbaginifolia x SC N. alata) hybrids. Expression levels and pollination behavior of hybrids expressing E. coli RNaseI were compared to controls expressing SA2-RNase from N. alata. Immunoblot analysis and RNase activity assays showed that RNaseI and SA2-RNase were expressed at comparable levels. However, expression of SA2-RNase caused rejection of N. plumbaginifolia pollen, whereas expression of RNaseI did not. Thus, in this system, RNase activity alone is not sufficient for rejection of N. plumbaginifolia pollen. The results suggest that S-RNases may be specially adapted to function in pollen rejection.

High pre-transplant soluble CD30 levels are predictive of the grade of rejection.

Science.gov (United States)

Rajakariar, Ravindra; Jivanji, Naina; Varagunam, Mira; Rafiq, Mohammad; Gupta, Arun; Sheaff, Michael; Sinnott, Paul; Yaqoob, M M

2005-08-01

In renal transplantation, serum soluble CD30 (sCD30) levels in graft recipients are associated with increased rejection and graft loss. We investigated whether pre-transplant sCD30 concentrations are predictive of the grade of rejection. Pre-transplant sera of 51 patients with tubulointerstitial rejection (TIR), 16 patients with vascular rejection (VR) and an age-matched control group of 41 patients with no rejection (NR) were analyzed for sCD30. The transplant biopsies were immunostained for C4d. The median sCD30 level was significantly elevated in the group with VR (248 Units (U)/mL, range: 92-802) when compared with TIR (103 U/mL, range: 36-309, psCD30 levels compared to NR. Based on C4d staining, a TH2 driven process, the median sCD30 levels were significantly raised in C4d+ patients compared with C4d- group (177 U/mL vs. 120 U/mL, psCD30 levels measured at time of transplantation correlate with the grade of rejection. High pre-transplant levels are associated with antibody-mediated rejection which carries a poorer prognosis. sCD30 could be another tool to assess immunological risk prior to transplantation and enable a patient centered approach to immunosuppression.

Maternal Predictors of Rejecting Parenting and Early Adolescent Antisocial Behavior

OpenAIRE

Trentacosta, Christopher J.; Shaw, Daniel S.

2007-01-01

The present study examined relations among maternal psychological resources, rejecting parenting, and early adolescent antisocial behavior in a sample of 231 low-income mothers and their sons with longitudinal assessments from age 18 months to 12 years. The maternal resources examined were age at first birth, aggressive personality, and empathy. Each of the maternal resources predicted rejecting parenting during early childhood in structural equation models that controlled for toddler difficu...

Calibration-free optical chemical sensors

Science.gov (United States)

DeGrandpre, Michael D.

2006-04-11

An apparatus and method for taking absorbance-based chemical measurements are described. In a specific embodiment, an indicator-based pCO2 (partial pressure of CO2) sensor displays sensor-to-sensor reproducibility and measurement stability. These qualities are achieved by: 1) renewing the sensing solution, 2) allowing the sensing solution to reach equilibrium with the analyte, and 3) calculating the response from a ratio of the indicator solution absorbances which are determined relative to a blank solution. Careful solution preparation, wavelength calibration, and stray light rejection also contribute to this calibration-free system. Three pCO2 sensors were calibrated and each had response curves which were essentially identical within the uncertainty of the calibration. Long-term laboratory and field studies showed the response had no drift over extended periods (months). The theoretical response, determined from thermodynamic characterization of the indicator solution, also predicted the observed calibration-free performance.

Main-Reflector Manufacturing Technology for the Deep Space Optical Communications Ground Station

Science.gov (United States)

Britcliffe, M. J.; Hoppe, D. J.

2001-01-01

The Deep Space Network (DSN) has plans to develop a 10-m-diameter optical communications receiving station. The system uses the direct detection technique, which has much different requirements from a typical astronomical telescope. The receiver must operate in daylight and nighttime conditions. This imposes special requirements on the optical system to reject stray light from the Sun and other sources. One of the biggest challenges is designing a main-reflector surface that meets these requirements and can be produced at a reasonable cost. The requirements for the performance of the reflector are presented. To date, an aspherical primary reflector has been assumed. A reflector with a spherical reflector has a major cost advantage over an aspherical design, with no sacrifice in performance. A survey of current manufacturing techniques for optical mirrors of this type was performed. Techniques including solid glass, lightweight glass, diamond-turned aluminum, and composite mirrors were investigated.

Coupled thermo-elastic and optical performance analyses of a reflective baffle for the BepiColombo laser altimeter (BELA) receiver

Science.gov (United States)

Heesel, E.; Weigel, T.; Lochmatter, P.; Rugi Grond, E.

2017-11-01

For the BepiColombo mission, the extreme thermal environment around Mercury requires good heat shields for the instruments. The BepiColombo Laser altimeter (BELA) Receiver will be equipped with a specular reflective baffle in order to limit the solar power impact. The design uses a Stavroudis geometry with alternating elliptical and hyperbolic vanes to reflect radiation at angles >38° back into space. The thermal loads on the baffle lead to deformations, and the resulting changes in the optical performance can be modeled by ray-tracing. Conventional interfaces, such as Zernike surface fitting, fail to provide a proper import of the mechanical distortions into optical models. We have studied alternative models such as free form surface representations and compared them to a simple modeling approach with straight segments. The performance merit is presented in terms of the power rejection ratio and the absence of specular stray-light.

Remembering rejection: specificity and linguistic styles of autobiographical memories in borderline personality disorder and depression.

Science.gov (United States)

Rosenbach, Charlotte; Renneberg, Babette

2015-03-01

High levels of rejection sensitivity are assumed to be the result of early and prolonged experiences of rejection. Aim of this study was to investigate autobiographical memories of rejection in clinical samples high in rejection sensitivity (Borderline Personality Disorder, BPD, and Major Depressive Disorder, MDD) and to identify group differences in the quality of the memories. Memories of rejection were retrieved using an adapted version of the Autobiographical Memory Test (AMT; five positive cue words, five cue words referring to rejection). Specificity of memories and linguistic word usage was analyzed in 30 patients with BPD, 27 patients with MDD and 30 healthy controls. Patients with BPD retrieved less specific memories compared to the healthy control group, whereas patients with MDD did not differ from controls in this regard. The group difference was no longer significant when controlling for rejection sensitivity. Linguistic analysis indicated that compared to both other groups, patients with BPD showed a higher self-focus, used more anger-related words, referred more frequently to social environments, and rated memories of rejection as more relevant for today's life. Clinical symptoms were not assessed in the control group. Moreover, the written form of the AMT might reduce the total number of specific memories. The level of rejection sensitivity influenced the specificity of the retrieved memories. Analysis of linguistic styles revealed specific linguistic patterns in BPD compared to non-clinical as well as depressed participants. Copyright © 2014 Elsevier Ltd. All rights reserved.

PHOSPHATES REMOVAL FROM REJECT WATER FROM DIGESTION OF SLUDGE

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Elżbieta Sperczyńska

2016-06-01

Full Text Available The aim of the research work was to evaluate if coagulants used on technical scale are useful in phosphates removal from reject water. Effectiveness of phosphorus compounds removal from reject water from digestion of sewage sludge was examined. Selected prehydrolysed alkaline aluminium polychlorides were used. The results were compared to the ones obtained with aluminium sulphate. Reject water from digestion of sewage sludge form WWTP of 100 000 PE were examined. Commercial agents – prehydrolysed PAX 18, PAX XL10, PAX-XL1905 as well as aluminium sulphate were used. Various doses of coagulants: 0.7; 1.0; 1.5 – time higher than stoichiometric dose were applied. Stoichiometric dose was calculated based on chemical reaction of insoluble aluminium phosphate formation. Concentrations of Kiejdahl nitrogen (891 mgNKj/dm3, phosphates (125 mgPO43-/dm3 and organic compounds - COD (592 mgO2/dm3 in reject water were very high. The effectiveness of coagulation process increased as the doses of chemical agents increased. The most effective doses were the highest ones used during the experiment. The most effective agent was PAX 18 (96% removal efficiency. As the phosphates concentration decreased COD content declined simultaneously. Maximum COD removal (47% was obtained when highly alkaline PAX XL 1905 was used. Use of the lowest dose of Al2(SO43 allowed for 50% phosphates removal, whereas the lowest dose of PAX 18 decreased phosphates concentration by 83%.

Early and late humoral rejection: a clinicopathologic entity in two times.

Science.gov (United States)

Péfaur, J; Díaz, P; Panace, R; Salinas, P; Fiabane, A; Quinteros, N; Chea, R; Naranjo, E; Wurgaft, A; Beltran, E; Elgueta, S; Wegmann, M E; Gajardo, J G; Contreras, L

2008-11-01

Humoral rejection is an important cause of early and late graft loss. The late variant is difficult to diagnose and treat. There is a close correlation between sclerosing nephropathy and anti-HLA antibodies. We analyzed 113 renal allograft recipients between August 2004 and April 2007. Acute humoral rejection was defined as acute graft dysfunction in presence of donor-specific antibodies (DSA) detected by flow panel reactive antibodies (PRA) and/or C4d positive pericapilary tubules (PTC) detected histopathologically by immunofluorescent or immunoperoxidase at less than 3 months postransplantation. Late humoral rejection was defined as dysfunction occurring after 3 months postransplantation with histopathologic glomerulopathy or vasculopathy and positive C4d PTC. We included all patients who were diagnosed with early or late graft dysfunction and underwent biopsy, all of which were examined for C4d. Four patients had acute humoral rejection treated with IVIG or plasmapheresis. The patient and graft survivals were 100% and serum creatinine averaged 1.7 mg/dL. Three recipients experienced late humoral rejection at 3 to 10 years posttransplantation All received high-dose IVIG; one also was treated with thymoglobulin. Immunosuppression was switched to tacrolimus, mycophenolate mofetil, and steroids. Only one patient recovered renal function; the others returned to dialysis. Among seven patients only one had an actual PRA (>20%) and three showed 10% to 20%. However, six had a positive historical PRA of 10% to 50%. In conclusion, Recognition of acute humoral rejection has contributed to graft rescue by controlling alloantibody production through new specific immunosuppressive therapies in contrast with the clinical response to acute therapy, treatment of a chronic entity has shown poor outcomes, probably because antibody mediated chronic graft damage is already present when the late diagnosis is established by biopsy.

Kidney graft rejection studies with labeled platelets and lymphocytes

International Nuclear Information System (INIS)

Martin-Comin, J.

1986-01-01

The usefulness of In-111-labelled platelets and lymphocyte scintigraphy in acute kidney graft rejection is evaluated in 155 patients. Blood cells were labelled with 100-150 uCi of In-111-oxine and reinjected. Subsequently patients were scanned once daily from 2 hours post-reinjection up to a week. The graft/contralateral area activity ratio was calculated in all scans. It is concluded that In-111-labelled platelets scintigraphy is nowadays the method of choice for acute kidney graft rejection diagnosis, especially in patients under cyclosporine immunosuppression. (author)

Gene-Based Multiclass Cancer Diagnosis with Class-Selective Rejections

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Nisrine Jrad

2009-01-01

rejection scheme. The state of art multiclass algorithms can be considered as a particular case of the proposed algorithm where the number of decisions is given by the classes and the loss function is defined by the Bayesian risk. Two experiments are carried out in the Bayesian and the class selective rejection frameworks. Five genes selected datasets are used to assess the performance of the proposed method. Results are discussed and accuracies are compared with those computed by the Naive Bayes, Nearest Neighbor, Linear Perceptron, Multilayer Perceptron, and Support Vector Machines classifiers.

Role of Soluble ST2 as a Marker for Rejection after Heart Transplant

OpenAIRE

Lee, Ga Yeon; Choi, Jin-Oh; Ju, Eun-Seon; Lee, Yoo-Jung; Jeon, Eun-Seok

2016-01-01

Background and Objectives Endomyocardial biopsy is obligatory during the first year after heart transplant (HTx) for the surveillance of acute rejection. Previous attempts using cardiac biomarkers for the detection of rejection failed to show enough evidence to substitute endomyocardial biopsy. Therefore, this study sought the possibility of using soluble ST2 (sST2), a novel cardiovascular marker, as a surrogate marker for acute allograft rejection after HTx. Subjects and Methods A total of 4...

Position statement. The right to accept or reject an assignment. American Nurses Association.

Science.gov (United States)

1996-01-01

The American Nurses Association (ANA) believes that nurses should reject assignment that puts patients or themselves in serious, immediate jeopardy. ANA supports the nurses obligation to reject an assignment in these situations even where there is not a specific legal protection for rejecting such an assignment. The professional obligations to the nurse to safeguard clients are grounded in the ethical norms of the profession, the Standards of Clinical Nursing Practice and state nurse practice acts.

Uptake of donor lymphocytes treated with 8-methoxypsoralen and ultraviolet A light by recipient dendritic cells induces CD4{sup +}CD25{sup +}Foxp3{sup +} regulatory T cells and down-regulates cardiac allograft rejection

Energy Technology Data Exchange (ETDEWEB)

Zheng, De-Hua [Organ Transplant Center, Chinese PLA 309th Hospital, No. 17A Hei-Shan-Hu Road, Beijing 100091 (China); Dou, Li-Ping [Department of Hematology, Chinese PLA General Hospital, No. 28 Fu-Xing Road, Beijing 100853 (China); Wei, Yu-Xiang; Du, Guo-Sheng; Zou, Yi-Ping; Song, Ji-Yong; Zhu, Zhi-Dong; Cai, Ming; Qian, Ye-Yong [Organ Transplant Center, Chinese PLA 309th Hospital, No. 17A Hei-Shan-Hu Road, Beijing 100091 (China); Shi, Bing-Yi, E-mail: shibingyi@medmail.com.cn [Organ Transplant Center, Chinese PLA 309th Hospital, No. 17A Hei-Shan-Hu Road, Beijing 100091 (China)

2010-05-14

Extracorporeal photopheresis (ECP) is an effective immunomodulatory therapy and has been demonstrated to be beneficial for graft-vs-host disease and solid-organ allograft rejection. ECP involves reinfusion of a patient's autologous peripheral blood leukocytes treated ex vivo with 8-methoxypsoralen and UVA light radiation (PUVA). Previous studies focused only on ECP treatment of recipient immune cells. Our study is the first to extend the target of ECP treatment to donor immune cells. The results of in vitro co-culture experiments demonstrate uptake of donor PUVA-treated splenic lymphocytes (PUVA-SPs) by recipient immature dendritic cells (DCs). Phagocytosis of donor PUVA-SPs does not stimulate phenotype maturation of recipient DCs. In the same co-culture system, donor PUVA-SPs enhanced production of interleukin-10 and interferon-{gamma} by recipient DCs and impaired the subsequent capability of recipient DCs to stimulate recipient naive T cells. Phagocytosis of donor PUVA-SP (PUVA-SP DCs) by recipient DCs shifted T-cell responses in favor of T helper 2 cells. Infusion of PUVA-SP DCs inhibited cardiac allograft rejection in an antigen-specific manner and induced CD4{sup +}CD25{sup high}Foxp3{sup +} regulatory T cells. In conclusion, PUVA-SP DCs simultaneously deliver the donor antigen and the regulatory signal to the transplant recipient, and thus can be used to develop a novel DC vaccine for negative immune regulation and immune tolerance induction.

Film reject analysis and image quality in diagnostic Radiology Department of a Teaching hospital in Ghana

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J. Owusu-Banahene

2014-10-01

Full Text Available Patients usually undergo repeated X-ray examinations after their initial X-ray radiographs are rejected due to poor image quality. This subjects the patients to an excess radiation exposure and extra cost and necessitates the need to investigate the causes of reject. The use of reject analysis as part of the overall quality assurance programs in clinical radiography and radiology services is vital in the evaluation of image quality of a well-established practice. It is shown that, in spite of good quality control maintained by the Radiology Department of a Teaching hospital in Ghana, reject analysis performed on a number of radiographic films developed indicated 14.1% reject rate against 85.9% accepted films. The highest reject rate was 57.1 ± 0.7% which occurs in cervical spine and the lowest was7.7 ± 0.5% for lumbar spine. The major factors contributing to film rejection were found to be over exposure and patient positioning in cervical spine examinations. The most frequent examination was chest X-ray which accounts for about 42.2% of the total examinations. The results show low reject rates by considering the factors for radiographic rejection analysis in relation to both equipment functionality and film development in the facility.

Beneficial Immune Effects of Myeloid-Related Proteins in Kidney Transplant Rejection

NARCIS (Netherlands)

Rekers, N. V.; Bajema, I. M.; Mallat, M. J. K.; Petersen, B.; Anholts, J. D. H.; Swings, G. M. J. S.; van Miert, P. P. M. C.; Kerkhoff, C.; Roth, J.; Popp, D.; van Groningen, M. C.; Baeten, D.; Goemaere, N.; Kraaij, M. D.; Zandbergen, M.; Heidt, S.; van Kooten, C.; de Fijter, J. W.; Claas, F. H. J.; Eikmans, M.

2016-01-01

Acute rejection is a risk factor for inferior long-term kidney transplant survival. Although T cell immunity is considered the main effector in clinical acute rejection, the role of myeloid cells is less clear. Expression of S100 calcium-binding protein A8 (S100A8) and S100A9 was evaluated in 303

Specific feature of magnetooptical images of stray fields of magnets of various geometrical shapes

Science.gov (United States)

Ivanov, V. E.; Koveshnikov, A. V.; Andreev, S. V.

2017-08-01

Specific features of magnetooptical images (MOIs) of stray fields near the faces of prismatic hard magnetic elements have been studied. Attention has primarily been focused on MOIs of fields near faces oriented perpendicular to the magnetic moment of hard magnetic elements. With regard to the polar sensitivity, MOIs have practically uniform brightness and geometrically they coincide with the figures of the bases of the elements. With regard to longitudinal sensitivity, MOIs consist of several sectors, the number of which is determined by the number of angles of the image. Each angle is divided by the bisectrix into two sectors of different brightnesses; therefore, the MOI of a triangular magnet consists of three sectors. A rectangle consists of four sectors separated by the bisectrices of the interior angles. In all types of figures, these lines converge at the center of the figure and form a singular point of the source or sink type.

"I'm worth more than that": trait positivity predicts increased rejection of unfair financial offers.

Science.gov (United States)

Dunn, Barnaby D; Makarova, Dasha; Evans, David; Clark, Luke

2010-12-08

Humans react strongly to unfairness, sometimes rejecting inequitable proposals even if this sacrifices personal financial gain. Here we explored whether emotional dispositions--trait tendencies to experience positive or negative feelings--shape the rejection of unfair financial offers. Participants played an Ultimatum Game, where the division of a sum of money is proposed and the player can accept or reject this offer. Individuals high in trait positivity and low in trait negativity rejected more unfair offers. These relationships could not be explained by existing accounts which argue that rejection behaviour results from a failure to regulate negative emotions, or serves to arbitrate social relationships and identity. Instead, the relationship between dispositional affect and rejection behaviour may be underpinned by perceived self worth, with those of a positive disposition believing that they are "worth more than that" and those of a negative disposition resigning themselves to "taking the crumbs from under the table".

Entropy-Based Clutter Rejection for Intrawall Diagnostics

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Raffaele Solimene

2012-01-01

Full Text Available The intrawall diagnostic problem of detecting localized inhomogeneities possibly present within the wall is addressed. As well known, clutter arising from masonry structure can impair detection of embedded scatterers due to high amplitude reflections that wall front face introduces. Moreover, internal multiple reflections also can make it difficult ground penetrating radar images (radargramms interpretation. To counteract these drawbacks, a clutter rejection method, properly tailored on the wall features, is mandatory. To this end, here we employ a windowing strategy based on entropy measures of temporal traces “similarity.” Accordingly, instants of time for which radargramms exhibit entropy values greater than a prescribed threshold are “silenced.” Numerical results are presented in order to show the effectiveness of the entropy-based clutter rejection algorithm. Moreover, a comparison with the standard average trace subtraction is also included.

Performance Evaluation of Air-Based Heat Rejection Systems

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Hannes Fugmann

2015-01-01

Full Text Available On the basis of the Number of Transfer Units (NTU method a functional relation between electric power for fans/pumps and effectiveness in dry coolers and wet cooling towers is developed. Based on this relation, a graphical presentation method of monitoring and simulation data of heat rejection units is introduced. The functional relation allows evaluating the thermodynamic performance of differently sized heat rejection units and comparing performance among them. The method is used to evaluate monitoring data of dry coolers of different solar cooling field projects. The novelty of this approach is that performance rating is not limited by a design point or standardized operating conditions of the heat exchanger, but is realizable under flexible conditions.

Source-sink estimates of genetic introgression show influence of hatchery strays on wild chum salmon populations in Prince William Sound, Alaska.

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James R Jasper

Full Text Available The extent to which stray, hatchery-reared salmon affect wild populations is much debated. Although experiments show that artificial breeding and culture influence the genetics of hatchery salmon, little is known about the interaction between hatchery and wild salmon in a natural setting. Here, we estimated historical and contemporary genetic population structures of chum salmon (Oncorhynchus keta in Prince William Sound (PWS, Alaska, with 135 single nucleotide polymorphism (SNP markers. Historical population structure was inferred from the analysis of DNA from fish scales, which had been archived since the late 1960's for several populations in PWS. Parallel analyses with microsatellites and a test based on Hardy-Weinberg proportions showed that about 50% of the fish-scale DNA was cross-contaminated with DNA from other fish. These samples were removed from the analysis. We used a novel application of the classical source-sink model to compare SNP allele frequencies in these archived fish-scales (1964-1982 with frequencies in contemporary samples (2008-2010 and found a temporal shift toward hatchery allele frequencies in some wild populations. Other populations showed markedly less introgression, despite moderate amounts of hatchery straying. The extent of introgression may reflect similarities in spawning time and life-history traits between hatchery and wild fish, or the degree that hybrids return to a natal spawning area. The source-sink model is a powerful means of detecting low levels of introgression over several generations.

Adaptation of Rejection Algorithms for a Radar Clutter

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D. Popov

2017-09-01

Full Text Available In this paper, the algorithms for adaptive rejection of a radar clutter are synthesized for the case of a priori unknown spectral-correlation characteristics at wobbulation of a repetition period of the radar signal. The synthesis of algorithms for the non-recursive adaptive rejection filter (ARF of a given order is reduced to determination of the vector of weighting coefficients, which realizes the best effectiveness index for radar signal extraction from the moving targets on the background of the received clutter. As the effectiveness criterion, we consider the averaged (over the Doppler signal phase shift improvement coefficient for a signal-to-clutter ratio (SCR. On the base of extreme properties of the characteristic numbers (eigennumbers of the matrices, the optimal vector (according to this criterion maximum is defined as the eigenvector of the clutter correlation matrix corresponding to its minimal eigenvalue. The general type of the vector of optimal ARF weighting coefficients is de-termined and specific adaptive algorithms depending upon the ARF order are obtained, which in the specific cases can be reduced to the known algorithms confirming its authenticity. The comparative analysis of the synthesized and known algorithms is performed. Significant bene-fits are established in clutter rejection effectiveness by the offered processing algorithms compared to the known processing algorithms.

CD28 Family and Chronic Rejection: “To Belatacept...and Beyond!”

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Marcos V. Silva

2012-01-01

Full Text Available Kidneys are one of the most frequently transplanted human organs. Immunosuppressive agents may prevent or reverse most acute rejection episodes; however, the graft may still succumb to chronic rejection. The immunological response involved in the chronic rejection process depends on both innate and adaptive immune response. T lymphocytes have a pivotal role in chronic rejection in adaptive immune response. Meanwhile, we aim to present a general overview on the state-of-the-art knowledge of the strategies used for manipulating the lymphocyte activation mechanisms involved in allografts, with emphasis on T-lymphocyte costimulatory and coinhibitory molecules of the B7-CD28 superfamily. A deeper understanding of the structure and function of these molecules improves both the knowledge of the immune system itself and their potential action as rejection inducers or tolerance promoters. In this context, the central role played by CD28 family, especially the relationship between CD28 and CTLA-4, becomes an interesting target for the development of immune-based therapies aiming to increase the survival rate of allografts and to decrease autoimmune phenomena. Good results obtained by the recent development of abatacept and belatacept with potential clinical use aroused better expectations concerning the outcome of transplanted patients.

"I'm worth more than that": trait positivity predicts increased rejection of unfair financial offers.

Directory of Open Access Journals (Sweden)

Barnaby D Dunn

2010-12-01

Full Text Available Humans react strongly to unfairness, sometimes rejecting inequitable proposals even if this sacrifices personal financial gain. Here we explored whether emotional dispositions--trait tendencies to experience positive or negative feelings--shape the rejection of unfair financial offers. Participants played an Ultimatum Game, where the division of a sum of money is proposed and the player can accept or reject this offer. Individuals high in trait positivity and low in trait negativity rejected more unfair offers. These relationships could not be explained by existing accounts which argue that rejection behaviour results from a failure to regulate negative emotions, or serves to arbitrate social relationships and identity. Instead, the relationship between dispositional affect and rejection behaviour may be underpinned by perceived self worth, with those of a positive disposition believing that they are "worth more than that" and those of a negative disposition resigning themselves to "taking the crumbs from under the table".

COTRANSA simulation of Chinshan unit one generator load rejection test

International Nuclear Information System (INIS)

Wu, C.H.

1984-01-01

A simulation of the plant behavior during a BWR generator load rejection transient using Exxon Nuclear Company's COTRANSA code is presented in this paper. The results are compared to measurements obtained by Taiwan Power Company during a generator load rejection transient, initiated at full power condition, which was one of the Chinshan Unit 1 initial cycle startup tests. Good agreement between the COTRANSA predicted and the measured values, indicates that the COTRANSA code can simulate this transient satisfactorily

PARENTAL ACCEPTANCE / REJECTION AND EMOTIONAL INTELLIGENCE AMONG ADOLESCENTS WITH AND WITHOUT DELINQUENT BEHAVIOR

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Orhideja ŠURBANOVSKA

2017-10-01

Full Text Available Introduction This paper analyzes the parental acceptance or rejection and the emotional intelligence among adolescents with and without delinquent behavior. Objectives: The primary objective of this study is to explore the differences between parents’ acceptance/rejection (by mother and father, respectively and the emotional intelligence among adolescentswith and without delinquent behavior, as well as the correlation between parents’ acceptance/rejection (by mother and father, respectively and the emotional intelligence among minors with delinquent behavior. Methods: The survey was conducted on two groups of adolescents, that is, 30 respondents serving a prison sentence for minors and/or have been imposed an educational measure of referral to an Educational and Correctional Facility aged 14 to 18, and 40 respondents that are secondary school students at the same age. In this research, the terms minors and adolescents both refer to persons aged 14-18 years. All respondents were males. The following measuring instruments were used: Parental Acceptance/Rejection Questionnaire and a Questionnaire for Measuring Emotional Intelligence – 45. Results: Minors with and without delinquent behavior differ considerably in terms of perceiving parental acceptance (by the mother and by the father, aggressiveness, neglect and undifferentiated rejection. The feeling of being rejected by the parents is more common among minors with delinquent behavior than in those without such behavior. Furthermore, minors with delinquent behavior have lower emotional intelligence compared with their peers without delinquent behavior. Positive associations were found between parental acceptance and emotional intelligence. Conclusion: Minors with delinquent behavior have experienced lower acceptance and higher rejection from the parents and have lower emotional intelligence than their peers without delinquent behavior. In general, parental acceptance is associated with

The Lived Experience of Psoriasis Patients from Social Stigma and Rejection: A Qualitative Study.

Science.gov (United States)

Ghorbanibirgani, Alireza; Fallahi-Khoshknab, Masoud; Zarea, Kourosh; Abedi, Heidarali

2016-07-01

Psoriasis is a common, chronic skin disease that causes challenges such as stigma and labeling from both the community and individuals due to its effects on appearance. The objective of this study was to describe and explain the social stigma and rejection experienced by patients with psoriasis. The present research is a qualitative study with a hermeneutic phenomenological approach conducted among psoriasis patients referring to the dermatology clinic and ward of Imam Khomeini hospital in Ahvaz, Iran between June and December 2014. In this study, 15 patients with psoriasis were selected by purposeful sampling, and they were asked to express their experience of stigma and rejection. The data were collected through in-depth semi-structured interviews, and Diekelmann and colleagues' method was used for data analysis. After analysis of interviews, four themes were extracted: lack of social support, unrealistic and inappropriate labeling, rejection and isolation, and feeling of absurdity and futility. These can be indicative of the patients' experience from social stigma and rejection phenomena. Patients' experiences of stigma and rejection phenomena indicated that all aspects of their lives are affected. Moreover, these findings highlight the significance of stigma and rejection concepts in providing better care to these patients.

Neutral Pion Rejection at L2 using the CMS Endcap Preshower

CERN Document Server

Kyriakis, Aristotelis; Loukas, Demetrios; Mousa, Jehad; Seez, Christopher

1999-01-01

Applying a general Artificial Neural Network approach, we have examined the possibility of neutral pion rejection at the Level 2 Trigger stage ( L2) principally using information from the CMS Endcap Preshower. We have studied both pion/photon and pion/electron discrimination. For L2 the hope was to achieve some useful pion/electron discrimination for a high electron efficiency. For a single electron/photon efficiency of 95% the results show that no useful rejection of neutral pions against electrons/photons can be obtained using this algorithm alone, due to the presence of tracker material. If the efficiency is lowered or information from the tracker is available, the rejection can increase dramatically. This will be the case for off-line analyses.

Soluble CD30 for the prediction and detection of kidney transplant rejection.

Science.gov (United States)

Arjona, Alvaro

2009-09-01

Although safer and more effective immunosuppressants as well as enhanced immunosuppressive protocols are continuously being developed in order to increase graft survival, they come at the steep price of drug-related complications and important side effects. In addition, the value of panel reactive antibodies determination, which at present is the single most used indicator of an increased risk of transplant rejection, is now being reevaluated. Therefore, effective tailoring of immunosuppressive therapy minimizing the above-mentioned pitfalls requires the existence of dependable biomarkers that adequately monitor rejection risk both before and after transplantation. Here we review the data yielded by studies assessing the usefulness of measuring soluble CD30 levels (sCD30) in kidney transplant rejection. These data collectively show that sCD30 serum content has a considerable predictive/diagnostic value for acute rejection of renal grafts, particularly when measured a few days after transplantation. Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved.

Determination of hyperacute kidney rejection in different xenogeneic system by 133xenon washout technique

International Nuclear Information System (INIS)

Welter, H.; Schmidt, K.R.; Pfeifer, K.J.; Hammer, C.; Chaussy, C.

1980-01-01

1. 133 Xenon washout technique is suitable for studying all stages of xenogeneic kidney rejection. 2. Follow-up studies allow differentiation between kidney rejection and kidneys in shock. 3. Changes of intrarenal blood flow distribution correlate with the histologic changes caused by rejection. 4. Total blood flow measurements employing 133 xenon washout yield 10-20% lower values compared with venous outflow measurements. 5. Graft rejection in the xenogeneic cat-dog system can be significantly delayed by ALG pretreatment. 6. The beneficial effect of blood transfusion described in different clinical and experimental studies could not be found after pretreatment of dogs with fox red blood cells. (orig.)

Prefrontal recruitment during social rejection predicts greater subsequent self-regulatory imbalance and impairment: neural and longitudinal evidence.

Science.gov (United States)

Chester, David S; DeWall, C Nathan

2014-11-01

Social rejection impairs self-regulation, yet the neural mechanisms underlying this relationship remain unknown. The right ventrolateral prefrontal cortex (rVLPFC) facilitates self-regulation and plays a robust role in regulating the distress of social rejection. However, recruiting this region's inhibitory function during social rejection may come at a self-regulatory cost. As supported by prominent theories of self-regulation, we hypothesized that greater rVLPFC recruitment during rejection would predict a subsequent self-regulatory imbalance that favored reflexive impulses (i.e., cravings), which would then impair self-regulation. Supporting our hypotheses, rVLPFC activation during social rejection was associated with greater subsequent nucleus accumbens (NAcc) activation and lesser functional connectivity between the NAcc and rVLPFC to appetitive cues. Over seven days, the effect of daily felt rejection on daily self-regulatory impairment was exacerbated among participants who showed a stronger rVLPFC response to social rejection. This interactive effect was mirrored in the effect of daily felt rejection on heightened daily alcohol cravings. Our findings suggest that social rejection likely impairs self-regulation by recruiting the rVLPFC, which then tips the regulatory balance towards reward-based impulses. Copyright © 2014 Elsevier Inc. All rights reserved.

Long-term results of total lymphoid irradiation in the treatment of cardiac allograft rejection

International Nuclear Information System (INIS)

Wolden, Suzanne L.; Tate, David J.; Hunt, Sharon A.; Strober, Samuel; Hoppe, Richard T.

1997-01-01

Purpose: To evaluate the short and long-term effects of total lymphoid irradiation (TLI) in the treatment of cardiac transplant rejection. Methods and Materials: Between 1986 and 1995, 48 courses of TLI were delivered to 47 cardiac transplant patients. In 37 patients, TLI was administered for intractable allograft rejection despite conventional therapy while 10 patients received TLI prophylactically. The prescribed radiation dose was 8 Gy in 0.8 Gy fractions twice weekly to mantle and inverted-Y plus spleen fields. Postirradiation follow-up ranged from 6 months to 9.1 years, with a mean of 3.1 years. Results: The actual mean dose was 7.3 Gy delivered over a mean of 39 days. Fifty-six percent of patients required treatment delay or abbreviation because of thrombocytopenia, leukopenia, infection, or unrelated problems. In patients treated for intractable rejection, rejection rates dropped from 0.46 to 0.14 and to 0.06 episodes/patient/month before, during, and after TLI (p < 0.0001). Rejection rates continued to drop throughout follow-up. Prednisone requirements decreased from 0.41 mg/kg before treatment to 0.21 mg/kg afterward (p < 0.0001). The ratio of helper to cytotoxic-suppressor T-cells decreased during TLI from 1.33 to 0.89, and remained low at 0.44, 2-4 months after treatment. Infection rates were not increased and two patients developed malignancy. Rejection rates were high during prophylactic treatment and this protocol was abandoned. Three-year actuarial survival after irradiation was 60% for patients with intractable rejection and 70% for the prophylactic cohort. Conclusion: TLI is an effective treatment for control of intractable cardiac rejection. Episodes of rejection and steroid dosage requirements are decreased for up to 9.1 years. A possible mechanism of action is long term alteration in T-lymphocyte subsets. Patients experience transient bone marrow suppression but no increase in infection or bleeding. Long-term complications of TLI are not

Neutron measurements in the stray field produced by 158 GeV/c lead ion beams

International Nuclear Information System (INIS)

Agosteo, S.; Birattari, C.; Foglio Para, A.; Nava, E.; Silari, M.; Ulrici, L.

1997-01-01

This paper discusses measurements carried out at CERN in the stray radiation field produced by 158 GeV/c 208 Pb 82+ ions. The purpose was to test and intercompare the response of several detectors, mainly neutron measuring devices, and to determine the neutron spectral fluence as well as the microdosimetric (absorbed dose and dose equivalent) distributions in different locations around the shielding. Both active instruments and passive dosimeters were employed, including different types of Andersson-Braun rem counters, a tissue equivalent proportional counter, a set of superheated drop detectors, a Bonner sphere system and different types of ion chambers. Activation measurements with 12 C plastic scintillators and with 32 S pellets were also performed to assess the neutron yield of high energy lead ions interacting with a thin gold target. The results are compared with previous measurements and with measurements made during proton runs. (author)

Responder Feelings in a Three-Player Three-Option Ultimatum Game: Affective Determinants of Rejection Behavior

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Hans-Rüdiger Pfister

2012-02-01

Full Text Available This paper addresses the role of affect and emotions in shaping the behavior of responders in the ultimatum game. A huge amount of research shows that players do not behave in an economically rational way in the ultimatum game, and emotional mechanisms have been proposed as a possible explanation. In particular, feelings of fairness, anger and envy are likely candidates as affective determinants. We introduce a three-player ultimatum game with three-options, which permits the responder to either penalize the proposer or to penalize a third party by rejecting offers. This allows for partially distinguishing rejections due to a retaliation motive driven by anger towards the proposer from rejections due to inequity aversion driven by feelings of envy towards a third party. Results from two experiments suggest that responders experience feelings of dissatisfaction and unfairness if their share is small in comparison to the proposer���s share; anger, then, may trigger rejections towards the proposer. Responders also experience dissatisfaction and envy when third party shares exceed their own shares; however, in contrast to anger, envy does not trigger rejections and is dissociated from the decision to accept or reject an offer. We conclude that acting upon anger is socially acceptable, whereas envy is not acceptable as a reason for action. Furthermore, we find that responders generally feel better after rejections, suggesting that rejections serve to regulate one’s affective state.

Noninvasive detection of rejection of transplanted hearts with indium-111-labeled lymphocytes

International Nuclear Information System (INIS)

Eisen, H.J.; Eisenberg, S.B.; Saffitz, J.E.; Bolman, R.M. III; Sobel, B.E.; Bergmann, S.R.

1987-01-01

To determine whether cardiac transplant rejection can be detected noninvasively with indium-111 ( 111 In)-labeled lymphocytes, we studied 11 dogs with thoracic heterotopic cardiac transplants without immunosuppression and five dogs with transplants treated with cyclosporine (10 mg/kg/day) and prednisone (1 mg/kg/day). All were evaluated sequentially with gamma scintigraphy after administration of 150 to 350 muCi of autologous 111 In-lymphocytes. Technetium-99m-labeled red blood cells (1 to 3 mCi) were used for correction of radioactivity in the blood pool attributable to circulating labeled lymphocytes. Lymphocyte infiltration was quantified as the ratio of indium in the myocardium of the transplant or native heart compared with that in blood (indium excess, IE). Results were correlated with mechanical and electrical activity of allografts and with histologic findings in sequential biopsy specimens. In untreated dogs (n = 11), IE was 15.5 +/- 7.0 (SD) in transplanted hearts undergoing rejection and 0.4 +/- 1.1 in native hearts on the day before animals were killed. In dogs treated with cyclosporine and prednisone (n = 5), IE was minimal in allografts during the course of immunosuppression (0.8 +/- 0.4) and increased to 22.9 +/- 11.1 after immunosuppression was stopped. Scintigraphic criteria of rejection (IE greater than 2 SD above that in native hearts) correlated with results of biopsies indicative of rejection and appeared before electrophysiologic or mechanical manifestations of dysfunction. Thus infiltration of labeled lymphocytes in allografts, indicative of rejection, is detectable noninvasively by gamma scintigraphy and provides a sensitive approach potentially applicable to clinical monitoring for early detection of rejection and guidance for titration of immunosuppressive measures

Culture-Based Rejection of Taboo-Infringing Imports

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Brice William D.

2017-09-01

Full Text Available This empirical study analyzes the cultural basis of the United States market response to imported Spanish products that seem to violate strongly-held cultural taboos. Survey responses were obtained from students in two contrasting majors, Art and Business, in two distinct cities and universities, i.e. Little Rock at the University of Arkansas, and Dominguez Hills at California State University. The study focused on a baby doll marketed to piggy-back on the new movement towards breastfeeding babies. Although accepted in its original European market, the United States media reports strong moral objections to this product among U. S. citizens. The toy was overwhelmingly rejected in some, but not all, population sub-groups. This study attempts to discern the cultural basis for product rejection by comparing responses between regions, college majors, genders and gender/major combinations. Differences in acceptance between groups are correlated with specific cultural constructs.

'The Unhealthy Other': How vaccine rejecting parents construct the vaccinating mainstream.

Science.gov (United States)

Attwell, Katie; Smith, David T; Ward, Paul R

2018-03-14

To address the phenomenon of vaccine hesitancy and rejection, researchers increasingly recognise the need to engage with the social context of parents' decision-making. This study examines how vaccine rejecting parents socially construct the vaccinating mainstream in opposition to themselves. We analyse qualitative data from interviews with parents in Adelaide, South Australia. Applying insights from Social Identity Theory (SIT), we show how these parents bolster their own sense of identity and self-belief by employing a discourse that casts vaccinators as an Unhealthy Other. We demonstrate how the parents identify vaccination as a marker of parental conformity to the 'toxic practices of mass industrial society', linking it to other ways in which membership of the consumerist mainstream requires individuals to 'neglect their health.' This is explored through themes of appearance, diet, (over) consumption of pharmaceuticals, inadequate parenting values and wilful or misguided ignorance. This construction of the Unhealthy Other elevates the self-concept of vaccine hesitant and rejecting parents, who see themselves as part of an enlightened, but constantly besieged, group of healthy and virtuous parents. It is common for the vaccinating mainstream to present vaccine hesitant and rejecting parents as a group subject to epistemic closure, groupthink, confirmation bias and over-confidence in their own expertise. However, vaccine hesitant and rejecting parents also see mainstream society as a group-a much larger one-subject to the same problems. We suggest the need to mitigate the 'groupness' of vaccination and non-vaccination by extending the practice of vaccination to recognisable practitioners of holistic health. Copyright © 2018 Elsevier Ltd. All rights reserved.

Background rejection in NEXT using deep neural networks

CERN Document Server

Renner, J.

2017-01-01

We investigate the potential of using deep learning techniques to reject background events in searches for neutrinoless double beta decay with high pressure xenon time projection chambers capable of detailed track reconstruction. The differences in the topological signatures of background and signal events can be learned by deep neural networks via training over many thousands of events. These networks can then be used to classify further events as signal or background, providing an additional background rejection factor at an acceptable loss of efficiency. The networks trained in this study performed better than previous methods developed based on the use of the same topological signatures by a factor of 1.2 to 1.6, and there is potential for further improvement.

Background rejection in NEXT using deep neural networks

International Nuclear Information System (INIS)

Renner, J.; Farbin, A.; Vidal, J. Muñoz; Benlloch-Rodríguez, J. M.; Botas, A.

2017-01-01

Here, we investigate the potential of using deep learning techniques to reject background events in searches for neutrinoless double beta decay with high pressure xenon time projection chambers capable of detailed track reconstruction. The differences in the topological signatures of background and signal events can be learned by deep neural networks via training over many thousands of events. These networks can then be used to classify further events as signal or background, providing an additional background rejection factor at an acceptable loss of efficiency. The networks trained in this study performed better than previous methods developed based on the use of the same topological signatures by a factor of 1.2 to 1.6, and there is potential for further improvement.

Ventricular function during the acute rejection of heterotopic transplanted heart: Gated blood pool studies

International Nuclear Information System (INIS)

Valette, H.; Bourguignon, M.H.; Desruennes, M.; Merlet, P.; Le Guludec, D.; Syrota, A.

1991-01-01

Twenty patients who had undergone a heterotopic heart transplant were studied prospectively to determine the relationship between rejection and ventricular dysfunction assessed from gated blood pool studies. A fully automated method for detecting ventricular edges was implemented; its success rate for the grafted left and right ventricles was 94% and 77%, respectively. The parameters, peak ejection and filling rates, were calculated pixel per pixel using a two-harmonic Fourier algorithm and then averaged over the ventricular region of interest. Peak filling and ejection rates were closely related with the severity of the rejection, while the left ventricular ejection fraction was not. Peak filling rates of both ventricles were the indices closely related to the presence of moderate rejection. Despite the low number of patients, these data suggested that gated blood pool derived indices of ventricular function are associated with ventricular dysfunction resulting from myocarditis rejection. Radionuclide ventriculography provides parametric data which are accurate and reliable for the diagnosis of rejection. (orig.)

Comprehending emotional eating in obese youngsters: the role of parental rejection and emotion regulation.

Science.gov (United States)

Vandewalle, J; Moens, E; Braet, C

2014-04-01

The present study examined the role of emotion regulation in the relation between parental rejection and emotional eating of obese youngsters. Participants were 110 obese youngsters between the ages of 10 and 16 years who were referred to a Belgian treatment centre for obesity. Participants completed questionnaires assessing maternal and paternal rejection, emotion regulation strategies and emotional eating during their intake at the treatment centre. Bootstrapping procedure was used to test if emotion regulation mediated the relationship between maternal and paternal rejection on the one hand and emotional eating of the youngster on the other hand. Results revealed that the use of maladaptive emotion regulation strategies mediated the relation between maternal rejection and emotional eating. Paternal rejection was neither associated with the emotion regulation nor with the emotional eating of the youngster. The findings highlight the importance of assessing the emotional bond between mother and child and the emotion regulation of the youngster in the treatment of pediatric obesity.

Significance of {sup 99m}Tc-tin Colloid Scan in Rejection of Transplanted Kidney

Energy Technology Data Exchange (ETDEWEB)

Oh, Ha Young; Kim, Seung Taik; Park, Seon Yang; Kim, Sung Yang; Lee, Myung Chul; Cho, Bo Youn; Lee, Jung Sang; Koh, Chang Soon [Seoul National University College of Medicine, Seoul (Korea, Republic of)

1982-09-15

Renal transplant uptake of {sup 99m}Tc-tin colloid was evaluated in 26 patients. Seventy-seven examinations were performed comparing transplant with bone marrow activity, clinical and/or pathological diagnosis. There were 13 instances of acute rejection; 7 of these exhibited slight uptake of radiocolloid in the renal transplant, 1 had marked uptake, and 5 had no evidence of uptake. There were 7 instances of chronic rejection; 5 of which demonstrated marked transplant uptake of radiocolloid, 1 had slight uptake, and 1 had no evidence of uptake. There were 2 instances of acute tubular necrosis and 55 instances of normal transplant function, but none of these exhibited transplant uptake of radiocolloid. From the result, the uptake of {sup 99m}Tc-tin colloid by renal transplant appears to signal rejection as long as the vascular supply is not severely compromised. Acute rejection may be represented by slight radiocolloid uptake, and chronic rejection by marked uptake when compared to bone marrow activity.

High serum soluble CD30 does not predict acute rejection in liver transplant patients.

Science.gov (United States)

Matinlauri, I; Höckerstedt, K; Isoniemi, H

2006-12-01

Increased pre- and posttransplantation values of soluble CD30 (sCD30) have been shown to be associated with acute kidney transplant rejection. We sought to study whether high sCD30 could predict rejection early after liver transplantation. The study population included 54 consecutive liver transplant patients, whose samples were collected before liver transplantation and at discharge, which was at a mean time of 3 weeks after transplantation. During the first 6 months posttransplantation, 22 patients experienced an acute rejection episode. Serum sCD30 concentrations were measured by an enzyme-linked immunoassay; changes in serum sCD30 levels posttransplantation were also expressed as relative values compared with pretransplantation results. Liver patients before transplantation displayed higher serum sCD30 values compared with healthy controls: mean values +/- SD were 93 +/- 58 IU/mL vs 17 +/- 8 IU/mL, respectively. At 3 weeks after transplantation the mean sCD30 concentration in liver transplant patients decreased to 59 +/- 42 IU/mL (P = .005). The mean pretransplantation serum sCD30 value was slightly lower among rejecting vs nonrejecting patients: 78 +/- 43 IU/mL vs 104 +/- 65 IU/mL (P = NS). Posttransplantation values in both groups decreased significantly: 47 +/- 34 IU/mL in patients with rejection (P = .014) vs 69 +/- 45 IU/mL in patients without rejection (P = .012). The relative value at 3 weeks posttransplantation decreased slightly more among patients with vs without rejection (70% vs 88%; NS). No correlation was found between serum sCD30 and anti-HLA class I antibodies or crossmatch positivity. In conclusion, neither pre- nor posttransplantation sCD30 levels were associated with acute rejection in liver transplant patients.

Using 3D printed eggs to examine the egg-rejection behaviour of wild birds

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Branislav Igic

2015-05-01

Full Text Available The coevolutionary relationships between brood parasites and their hosts are often studied by examining the egg rejection behaviour of host species using artificial eggs. However, the traditional methods for producing artificial eggs out of plasticine, plastic, wood, or plaster-of-Paris are laborious, imprecise, and prone to human error. As an alternative, 3D printing may reduce human error, enable more precise manipulation of egg size and shape, and provide a more accurate and replicable protocol for generating artificial stimuli than traditional methods. However, the usefulness of 3D printing technology for egg rejection research remains to be tested. Here, we applied 3D printing technology to the extensively studied egg rejection behaviour of American robins, Turdus migratorius. Eggs of the robin’s brood parasites, brown-headed cowbirds, Molothrus ater, vary greatly in size and shape, but it is unknown whether host egg rejection decisions differ across this gradient of natural variation. We printed artificial eggs that encompass the natural range of shapes and sizes of cowbird eggs, painted them to resemble either robin or cowbird egg colour, and used them to artificially parasitize nests of breeding wild robins. In line with previous studies, we show that robins accept mimetically coloured and reject non-mimetically coloured artificial eggs. Although we found no evidence that subtle differences in parasitic egg size or shape affect robins’ rejection decisions, 3D printing will provide an opportunity for more extensive experimentation on the potential biological or evolutionary significance of size and shape variation of foreign eggs in rejection decisions. We provide a detailed protocol for generating 3D printed eggs using either personal 3D printers or commercial printing services, and highlight additional potential future applications for this technology in the study of egg rejection.

Using 3D printed eggs to examine the egg-rejection behaviour of wild birds

Science.gov (United States)

Nunez, Valerie; Voss, Henning U.; Croston, Rebecca; Aidala, Zachary; López, Analía V.; Van Tatenhove, Aimee; Holford, Mandë E.; Shawkey, Matthew D.; Hauber, Mark E.

2015-01-01

The coevolutionary relationships between brood parasites and their hosts are often studied by examining the egg rejection behaviour of host species using artificial eggs. However, the traditional methods for producing artificial eggs out of plasticine, plastic, wood, or plaster-of-Paris are laborious, imprecise, and prone to human error. As an alternative, 3D printing may reduce human error, enable more precise manipulation of egg size and shape, and provide a more accurate and replicable protocol for generating artificial stimuli than traditional methods. However, the usefulness of 3D printing technology for egg rejection research remains to be tested. Here, we applied 3D printing technology to the extensively studied egg rejection behaviour of American robins, Turdus migratorius. Eggs of the robin’s brood parasites, brown-headed cowbirds, Molothrus ater, vary greatly in size and shape, but it is unknown whether host egg rejection decisions differ across this gradient of natural variation. We printed artificial eggs that encompass the natural range of shapes and sizes of cowbird eggs, painted them to resemble either robin or cowbird egg colour, and used them to artificially parasitize nests of breeding wild robins. In line with previous studies, we show that robins accept mimetically coloured and reject non-mimetically coloured artificial eggs. Although we found no evidence that subtle differences in parasitic egg size or shape affect robins’ rejection decisions, 3D printing will provide an opportunity for more extensive experimentation on the potential biological or evolutionary significance of size and shape variation of foreign eggs in rejection decisions. We provide a detailed protocol for generating 3D printed eggs using either personal 3D printers or commercial printing services, and highlight additional potential future applications for this technology in the study of egg rejection. PMID:26038720

Perceived parental rejection mediates the effects of previous ...

African Journals Online (AJOL)

Behavioural problems, parental rejection scores and child abuse ... evaluated by the Child Behavior Checklist (parental version), the Memories of Parental Rearing ... However, mental illness had no moderating effect on these relationships.

Utility of indium-111 labelled autologous platelets in the diagnosis of renal graft rejection

International Nuclear Information System (INIS)

Martin-Comin, J.; Roca, M.; Grino, J.M.; Paradell, C.; Caralps, A.

1982-01-01

The usefulness of In-111 labelled autologous platelets in the diagnosis of renal graft rejection was studied. The method is based on imaging of the graft area at 4, 24, 48 and 72 hours after the injection of the labelled cells. The study was done in 21 renal cadaveric transplant recipients: control group: four patients without evidence of rejection. No platelet uptake was observed in any of them. Study group: in 13 patients with acute rejection and 1 with chronic rejection graft tracer uptake was seen. In the 3 others with a non-immunological sudden impairment of renal function, no activity was detected in graft area. Changes in renal platelet trapping correlated with response to antirejection therapy

The embodiment design of the heat rejection system for the portable life support system

Science.gov (United States)

Stuckwisch, Sue; Francois, Jason; Laughlin, Julia; Phillips, Lee; Carrion, Carlos A.

1994-01-01

The Portable Life Support System (PLSS) provides a suitable environment for the astronaut in the Extravehicular Mobility Unit (EMU), and the heat rejection system controls the thermal conditions in the space suit. The current PLSS sublimates water to the space environment; therefore, the system loses mass. Since additional supplies of fluid must be available on the Space Shuttle, NASA desires a closed heat rejecting system. This document presents the embodiment design for a radiative plate heat rejection system without mass transfer to the space environment. This project will transform the concept variant into a design complete with material selection, dimensions of the system, layouts of the heat rejection system, suggestions for manufacturing, and financial viability.

Analysis of the accuracy of different laboratory methods for the diagnosis of intestinal parasites from stray and domiciled cats (Felis catus domesticus in Goiânia, Goiás, Brazil

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Jaqueline Ataíde Silva Lima

2018-02-01

Full Text Available Abstract Cats are carriers of zoonotic agents to humans, including intestinal parasites. The purpose of this study was to analyze the accuracy of different laboratory methods for the diagnosis of intestinal parasites. Fecal samples were processed by the Willis, Sheather, Faust and Hoffman-Janer-Pons-Lutz (HJPL methods. Accuracy analysis was performed determining the sensitivity, specificity, positive and negative predictive value and Kappa. A total of 149 fecal samples were collected, 65 from stray cats and 84 from domiciled cats. The prevalence of intestinal parasites in stray cats was 60% while in domiciled cats it was 17%. In the analysis of accuracy, the techniques that showed the greatest accuracy for Ancylostomids were Willis and Faust, for Cystoisospora spp. Sheather with Faust or HPJL, and Toxoplasma gondii/Hammondia hammondi the association between Willis and Faust. Therefore, for a reliable evaluation of the prevalence of intestinal parasites, at least two different techniques should be used in parasitological exams of feces.

Einstein's Revolutionary Light-Quantum Hypothesis

Science.gov (United States)

Stuewer, Roger H.

2005-05-01

The paper in which Albert Einstein proposed his light-quantum hypothesis was the only one of his great papers of 1905 that he himself termed ``revolutionary.'' Contrary to widespread belief, Einstein did not propose his light-quantum hypothesis ``to explain the photoelectric effect.'' Instead, he based his argument for light quanta on the statistical interpretation of the second law of thermodynamics, with the photoelectric effect being only one of three phenomena that he offered as possible experimental support for it. I will discuss Einstein's light-quantum hypothesis of 1905 and his introduction of the wave-particle duality in 1909 and then turn to the reception of his work on light quanta by his contemporaries. We will examine the reasons that prominent physicists advanced to reject Einstein's light-quantum hypothesis in succeeding years. Those physicists included Robert A. Millikan, even though he provided convincing experimental proof of the validity of Einstein's equation of the photoelectric effect in 1915. The turning point came after Arthur Holly Compton discovered the Compton effect in late 1922, but even then Compton's discovery was contested both on experimental and on theoretical grounds. Niels Bohr, in particular, had never accepted the reality of light quanta and now, in 1924, proposed a theory, the Bohr-Kramers-Slater theory, which assumed that energy and momentum were conserved only statistically in microscopic interactions. Only after that theory was disproved experimentally in 1925 was Einstein's revolutionary light-quantum hypothesis generally accepted by physicists---a full two decades after Einstein had proposed it.

Research on rejection performance of reverse osmosis to manganese in simulated radioactive wastewater

International Nuclear Information System (INIS)

Kong Jinsong; Wang Xiaowei

2012-01-01

In order to reveal the performance of reverse osmosis applied in the radioactive wastewater treatment, treatment experiments are carried out on a pilot RO equipment using wastewater containing manganese nuclide. Results show that the rejection ratio of RO to manganese is almost not influenced by the operation pressure and the ration of reclaiming, and has no direct relation with the salt rejection ratio. The ratio of manganese rejection is more than 95% and can meet the requirement on the disposal of radioactive wastewater produced by pressurized water reactors. (authors)

Attachment Style and Rejection Sensitivity: The Mediating Effect of Self-Esteem and Worry Among Iranian College Students

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Samira Khoshkam

2012-08-01

Full Text Available The present study evaluated the relations between anxious attachment styles and rejection sensitivity, and the potential mediating role of self-esteem and worry. A sample of 125 Iranian college students completed surveys assessing rejection sensitivity, attachment style, worry and self-esteem. Structural Equation Modeling (SEM analyses were conducted. Results show that there is a significant positive relationship between anxious attachment styles and rejection sensitivity. The study suggests that a higher score in anxious attachment styles is associated with a higher level of worry and lower level of self-esteem and it is also associated with higher level of rejection sensitivity. Furthermore, there is a positive significant relationship between worry and rejection sensitivity and there is a negative significant relationship between self-esteem and rejection sensitivity. Results indicate that self-esteem and worry mediate the relationship between anxious attachment styles and rejection sensitivity.

[Combined assay of soluble CD30 and hepatocyte growth factor for diagnosis of acute renal allograft rejection].

Science.gov (United States)

Li, Chuan-jiang; Yu, Li-xin; Xu, Jian; Fu, Shao-jie; Deng, Wen-feng; Du, Chuan-fu; Wang, Yi-bin

2008-02-01

To study the value of detection of both preoperative soluble CD30 (sCD30) and hepatocyte growth factor (HGF) level 5 days after transplantation in the diagnosis of acute rejection of renal allograft. Preoperative serum sCD30 levels and HGF level 5 days after transplantation were determined in 65 renal-transplant recipients using enzyme-linked immunosorbent assay. The recipients were divided according to the sCD30 levels positivity. Receiver operating characteristic (ROC) curves were used to assess the value of HGF level on day 5 posttransplantation for diagnosis of acute renal allograft rejection, and the value of combined assay of the sCD30 and HGF levels was also estimated. After transplantation, 26 recipients developed graft rejection and 39 had uneventful recovery without rejection. With the cut-off value of sCD30 of 120 U/ml, the positivity rate of sCD30 was significantly higher in recipients with graft rejection than in those without (61.5% vs 17.9%, Pacute rejection showed also significantly higher HGF levels on day 5 posttransplantation than those without rejection (Pacute renal allograft rejection, and at the cut-off value of 90 ug/L, the diagnostic sensitivity was 84.6% and specificity 76.9%. Evaluation of both the sCD30 and HGF levels significantly enhanced the diagnostic accuracy of acute graft rejection. Combined assay of serum sCD30 and HGF levels offers a useful means for diagnosis of acute renal allograft rejection.

Diagnosis of cardiac allograft rejection with indium-111 labeled platelets in cyclosporin treated rats

International Nuclear Information System (INIS)

Fawwaz, R.A.; Iga, C.; Hardy, M.A.; Alderson, P.O.

1984-01-01

Rejection of heart transplants remains difficult to diagnose. Indium-111 (In-111) labeled lymphocytes accumulate in rat cardiac allografts when recipients are treated with Cyclosporin (Cy), even in the absence of clinical rejection. This presumably occurs because of the non-specific 'interstitial infiltration' caused by Cy. This study examines the usefulness of In-111 labeled platelets in differentiating experimental cardiac allograft rejection from Cy-induced tissue changes. The authors initially examined the migration patterns of syngeneic In-111 labeled platelets in groups of Lewis recipients of ACI cardiac allografts treated with IM Cy (10mg/kg) for 6-14 days. In addition, 10 control animals were not immunosuppressed, and 10 were treated with Cy but received Lewis cardiac isografts. Syngeneic In-111 platelets were injected IV into each animal 24 hours prior to sacrifice. Three to five rats from each group were killed at 3 ,7, 14, 21 and 28 days after transplantation and the % ID/gm in the transplanted hearts and native hearts were determined and correlated with histopathology. Untreated Lewis recipients rejected ACI hearts in 6.5 +- 0.4 days while Cy prolonged allograft survival in a variable fashion. In-111 platelet accumulation correlated well with the degree of rejection determined independently by histopathology. No significant In-111 platelet accumulation was detected in non-rejecting cardiac transplants or in native hearts in Cy treated or control animals. The results suggest that In-111 labeled platelets will be an effective agent for diagnosis of cardiac rejection, even in the presence of Cy treatment

Music genre recognition with risk and rejection

DEFF Research Database (Denmark)

Sturm, Bob L.

2013-01-01

We explore risk and rejection for music genre recognition (MGR) within the minimum risk framework of Bayesian classification. In this way, we attempt to give an MGR system knowledge that some misclassifications are worse than others, and that deferring classification to an expert may be a better...

A comparative study of boron and arsenic (III) rejection from brackish water by reverse osmosis membranes

KAUST Repository

Teychene, Benoî t; Collet, Gaelle; Gallard, Hervé ; Croue, Jean Philippe

2013-01-01

This study aims to compare at lab-scale the rejection efficiency of several reverse osmosis membranes (RO) toward arsenic (III) and boron during the filtration of a synthetic brackish water. The effect of pH and operating conditions on the rejection of each RO membrane was studied. Two types of membrane were investigated: "brackish water" and "sea water" membranes. Our results showed that the metalloid rejection depends on the membrane type, pH and transmembrane pressure applied. Increasing pH above the dissociation constant (pKa) of each specie improves significantly the metalloid rejection by RO membranes, whatever the membrane type. Moreover, at identical operating conditions (pH, transmembrane pressure), results showed that the brackish water membranes have a higher water flux and exhibit lower metalloid rejection. The highest As(III) rejection value for the tested brackish water membranes was 99% obtained at pH = 9.6 and 40 bars, whereas it was found that the sea water RO membranes could highly reject As(III), more than 99%, even at low pH and low pressure (pH = 7.6 and 24 bars).Regarding Boron rejection, similar conclusions could be drawn. The sea water RO membranes exert higher removal, with a high rejection value above 96% over the tested conditions. More generally, this study showed that, whatever the operating conditions or the tested membranes, the boron and As(III) permeate concentrations are below the WHO guidelines. In addition, new data about the boron and arsenic permeability of each tested RO membrane was brought thanks to a theoretical calculation. © 2012 Elsevier B.V.

Zbtb7a induction in alveolar macrophages is implicated in anti-HLA-mediated lung allograft rejection.

Science.gov (United States)

Nayak, Deepak K; Zhou, Fangyu; Xu, Min; Huang, Jing; Tsuji, Moriya; Yu, Jinsheng; Hachem, Ramsey; Gelman, Andrew E; Bremner, Ross M; Smith, Michael A; Mohanakumar, Thalachallour

2017-07-12

Chronic rejection significantly limits long-term success of solid organ transplantation. De novo donor-specific antibodies (DSAs) to mismatched donor human leukocyte antigen after human lung transplantation predispose lung grafts to chronic rejection. We sought to delineate mediators and mechanisms of DSA pathogenesis and to define early inflammatory events that trigger chronic rejection in lung transplant recipients and obliterative airway disease, a correlate of human chronic rejection, in mouse. Induction of transcription factor zinc finger and BTB domain containing protein 7a (Zbtb7a) was an early response critical in the DSA-induced chronic rejection. A cohort of human lung transplant recipients who developed DSA and chronic rejection demonstrated greater Zbtb7a expression long before clinical diagnosis of chronic rejection compared to nonrejecting lung transplant recipients with stable pulmonary function. Expression of DSA-induced Zbtb7a was restricted to alveolar macrophages (AMs), and selective disruption of Zbtb7a in AMs resulted in less bronchiolar occlusion, low immune responses to lung-restricted self-antigens, and high protection from chronic rejection in mice. Additionally, in an allogeneic cell transfer protocol, antigen presentation by AMs was Zbtb7a-dependent where AMs deficient in Zbtb7a failed to induce antibody and T cell responses. Collectively, we demonstrate that AMs play an essential role in antibody-induced pathogenesis of chronic rejection by regulating early inflammation and lung-restricted humoral and cellular autoimmunity. Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

A comparative study of boron and arsenic (III) rejection from brackish water by reverse osmosis membranes

KAUST Repository

Teychene, Benoît

2013-02-01

This study aims to compare at lab-scale the rejection efficiency of several reverse osmosis membranes (RO) toward arsenic (III) and boron during the filtration of a synthetic brackish water. The effect of pH and operating conditions on the rejection of each RO membrane was studied. Two types of membrane were investigated: "brackish water" and "sea water" membranes. Our results showed that the metalloid rejection depends on the membrane type, pH and transmembrane pressure applied. Increasing pH above the dissociation constant (pKa) of each specie improves significantly the metalloid rejection by RO membranes, whatever the membrane type. Moreover, at identical operating conditions (pH, transmembrane pressure), results showed that the brackish water membranes have a higher water flux and exhibit lower metalloid rejection. The highest As(III) rejection value for the tested brackish water membranes was 99% obtained at pH = 9.6 and 40 bars, whereas it was found that the sea water RO membranes could highly reject As(III), more than 99%, even at low pH and low pressure (pH = 7.6 and 24 bars).Regarding Boron rejection, similar conclusions could be drawn. The sea water RO membranes exert higher removal, with a high rejection value above 96% over the tested conditions. More generally, this study showed that, whatever the operating conditions or the tested membranes, the boron and As(III) permeate concentrations are below the WHO guidelines. In addition, new data about the boron and arsenic permeability of each tested RO membrane was brought thanks to a theoretical calculation. © 2012 Elsevier B.V.

Perturbations in the Urinary Exosome in Transplant Rejection

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Sigdel, Tara K.; NG, Yolanda; Lee, Sangho; Nicora, Carrie D.; Qian, Weijun; Smith, Richard D.; Camp, David G.; Sarwal, Minnie M.

2015-01-05

Background: Urine exosomes, vesicles exocytosed into urine by all renal epithelial cell types, occur under normal physiologic and disease states. Exosome contents may mirror disease-specific proteome perturbations in kidney injury. Analysis methodologies for the exosomal fraction of the urinary proteome were developed and for comparing the urinary exosomal fraction versus unfractionated proteome for biomarker discovery. Methods: Urine exosomes were isolated by centrifugal filtration from mid-stream, second morning void, urine samples collected from kidney transplant recipients with and without biopsy matched acute rejection. The proteomes of unfractionated whole urine (Uw) and urine exosomes (Uexo) underwent mass spectrometry-based quantitative proteomics analysis. The proteome data were analyzed for significant differential protein abundances in acute rejection (AR). Results: Identifications of 1018 and 349 proteins, Uw and Uexo fractions, respectively, demonstrated a 279 protein overlap between the two urinary compartments with 25%(70) of overlapping proteins unique to Uexoand represented membrane bound proteins (p=9.31e-7). Of 349 urine exosomal proteins identified in transplant patients 220 were not previously identified in the normal urine exosomal fraction. Uexo proteins (11), functioning in the inflammatory / stress response, were more abundant in patients with biopsy-confirmed acute rejection, 3 of which were exclusive to Uexo. Uexo AR-specific biomarkers (8) were also detected in Uw, but since they were observed at significantly lower abundances in Uw, they were not significant for AR in Uw. Conclusions: A rapid urinary exosome isolation method and quantitative measurement of enriched Uexo proteins was applied. Urine proteins specific to the exosomal fraction were detected either in unfractionated urine (at low abundances) or by Uexo fraction analysis. Perturbed proteins in the exosomal compartment of urine collected from kidney transplant patients were

Mechanisms of allograft rejection of corneal endothelium

International Nuclear Information System (INIS)

Tagawa, Y.; Silverstein, A.M.; Prendergast, R.A.

1982-01-01

The local intraocular graft-vs.-host (GVH) reaction, involving the destruction of the corneal endothelial cells of the rabbit host by sensitized donor lymphoid cells, has been used to study the mechanism of corneal allograft rejection. Pretreatment of donor cells with a specific mouse monoclonal hybridoma anti-T cell antibody and complement suppresses the destructive reaction, suggesting that a cellular-immune mechanism is primarily involved. Pretreatment of donor cells with mitomycin-C completely abolishes the local GVH reaction, indicating that the effector lymphocytes must undergo mitosis within the eye before they can engage in target cell destruction. Finally, studies of the local GVH reaction in irradiated leukopenic recipients or in preinflamed rabbit eyes suggest that host leukocytes may contribute nonspecifically to enhance the destructive process. These studies show that the local ocular GVH reaction may provide a useful model for the study of the mechanisms involved in the rejection of corneal allografts

Patient-reported non-adherence and immunosuppressant trough levels are associated with rejection after renal transplantation.

Science.gov (United States)

Scheel, Jennifer; Reber, Sandra; Stoessel, Lisa; Waldmann, Elisabeth; Jank, Sabine; Eckardt, Kai-Uwe; Grundmann, Franziska; Vitinius, Frank; de Zwaan, Martina; Bertram, Anna; Erim, Yesim

2017-03-29

Different measures of non-adherence to immunosuppressant (IS) medication have been found to be associated with rejection episodes after successful transplantation. The aim of the current study was to investigate whether graft rejection after renal transplantation is associated with patient-reported IS medication non-adherence and IS trough level variables (IS trough level variability and percentage of sub-therapeutic IS trough levels). Patient-reported non-adherence, IS trough level variability, percentage of sub-therapeutic IS trough levels, and acute biopsy-proven late allograft rejections were assessed in 267 adult renal transplant recipients who were ≥12 months post-transplantation. The rate of rejection was 13.5%. IS trough level variability, percentage of sub-therapeutic IS trough levels as well as patient-reported non-adherence were all significantly and positively associated with rejection, but not with each other. Logistic regression analyses revealed that only the percentage of sub-therapeutic IS trough levels and age at transplantation remained significantly associated with rejection. Particularly, the percentage of sub-therapeutic IS trough levels is associated with acute rejections after kidney transplantation whereas IS trough level variability and patient-reported non-adherence seem to be of subordinate importance. Patient-reported non-adherence and IS trough level variables were not correlated; thus, non-adherence should always be measured in a multi-methodological approach. Further research concerning the best combination of non-adherence measures is needed.

Spectral anomaly methods for aerial detection using KUT nuisance rejection

International Nuclear Information System (INIS)

Detwiler, R.S.; Pfund, D.M.; Myjak, M.J.; Kulisek, J.A.; Seifert, C.E.

2015-01-01

This work discusses the application and optimization of a spectral anomaly method for the real-time detection of gamma radiation sources from an aerial helicopter platform. Aerial detection presents several key challenges over ground-based detection. For one, larger and more rapid background fluctuations are typical due to higher speeds, larger field of view, and geographically induced background changes. As well, the possible large altitude or stand-off distance variations cause significant steps in background count rate as well as spectral changes due to increased gamma-ray scatter with detection at higher altitudes. The work here details the adaptation and optimization of the PNNL-developed algorithm Nuisance-Rejecting Spectral Comparison Ratios for Anomaly Detection (NSCRAD), a spectral anomaly method previously developed for ground-based applications, for an aerial platform. The algorithm has been optimized for two multi-detector systems; a NaI(Tl)-detector-based system and a CsI detector array. The optimization here details the adaptation of the spectral windows for a particular set of target sources to aerial detection and the tailoring for the specific detectors. As well, the methodology and results for background rejection methods optimized for the aerial gamma-ray detection using Potassium, Uranium and Thorium (KUT) nuisance rejection are shown. Results indicate that use of a realistic KUT nuisance rejection may eliminate metric rises due to background magnitude and spectral steps encountered in aerial detection due to altitude changes and geographically induced steps such as at land–water interfaces

An Audit Of Rejected Repeated X-ray Films As A Quality Assurance ...

African Journals Online (AJOL)

To find out the causes, number, percentage and sizes of rejected radiographic filmswith a view of adopting measures that will reduce the rate and number of rejected films. Radiology Department of a University Teaching Hospital. Over a two-year period (1 April 2002 to 31 March 2004), the total number of x-ray films utilized ...

A simple and fast physics-based analytical method to calculate therapeutic and stray doses from external beam, megavoltage x-ray therapy.

Science.gov (United States)

Jagetic, Lydia J; Newhauser, Wayne D

2015-06-21

State-of-the-art radiotherapy treatment planning systems provide reliable estimates of the therapeutic radiation but are known to underestimate or neglect the stray radiation exposures. Most commonly, stray radiation exposures are reconstructed using empirical formulas or lookup tables. The purpose of this study was to develop the basic physics of a model capable of calculating the total absorbed dose both inside and outside of the therapeutic radiation beam for external beam photon therapy. The model was developed using measurements of total absorbed dose in a water-box phantom from a 6 MV medical linear accelerator to calculate dose profiles in both the in-plane and cross-plane direction for a variety of square field sizes and depths in water. The water-box phantom facilitated development of the basic physical aspects of the model. RMS discrepancies between measured and calculated total absorbed dose values in water were less than 9.3% for all fields studied. Computation times for 10 million dose points within a homogeneous phantom were approximately 4 min. These results suggest that the basic physics of the model are sufficiently simple, fast, and accurate to serve as a foundation for a variety of clinical and research applications, some of which may require that the model be extended or simplified based on the needs of the user. A potentially important advantage of a physics-based approach is that the model is more readily adaptable to a wide variety of treatment units and treatment techniques than with empirical models.

Synthesis of unsymmetrical dimethylhydrazine oxalate from rejected liquid rocket propellant

Science.gov (United States)

Mu, Xiaogang; Yang, Jingjing; Zhang, Youzhi

2018-02-01

The rejected liquid propellant unsymmetrical dimethylhydrazine (UDMH) was converted to UDMH oxalate, which has commercial value. The UDMH oxalate structure and stability were investigated by the Fourier transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, differential scanning calorimetry, and ultraviolet-visible spectrophotometric analysis. The results indicate that UDMH oxalate has good thermal and aqueous solution stability, a melting point of 144 °C, an initial decomposition temperature of 180 °C, and a peak wavelength of UV in aqueous solution at λ = 204 nm. This disposal method of rejected UDMH is highly efficient and environmentally safe.

Radiation therapy for renal transplant rejection refractory to pulse steroids and OKT3

International Nuclear Information System (INIS)

Noyes, William R.; Rodriguez, Rey; Knechtle, Stuart J.; Pirsch, John D.; Sollinger, Hans W.; D'Alessandro, Anthony M.; Chappell, Rick; Belzer, Folkert O.; Kinsella, Timothy J.

1996-01-01

Purpose: To determine the response rate and kidney graft survival following local irradiation to the transplanted renal graft undergoing persistent rejection after medical management including pulse steroids and OKT3. The role of radiation for renal transplant rejection after failure of OKT3 has not been previously reported. Methods and Materials: From July 1, 1988 to July 1, 1994, 72 consecutive patients with kidney graft rejection were treated with local irradiation to the transplanted renal graft following failure of medical management. All patients received pulse steroids and OKT3, an anti-CD3 immunosuppressant. Patients who failed to respond to methylprednisolone and OKT3 therapy were referred for radiation therapy. The median time from the diagnosis of rejection to irradiation was 8 days. All kidney grafts received local graft irradiation to a total of 8 Gy delivered in four daily fractions. Results: Sixty (83%) patients initially responded to radiotherapy at 7 days after completion of radiotherapy, as defined by a decrease in serum creatinine. Thirty-five responding patients have not experienced a second episode of graft rejection. Overall, 43 (60%) patients have renal graft survival, with a median follow-up of 16 months (range of 6-73 months). Conclusion: It is concluded that there is a subgroup of kidney graft patients undergoing graft rejection who are refractory to pulse steroids and OKT3 therapy where irradiation may be an effective modality with high rates of response and a moderate rate of graft survival. However, a prospective, randomized trial in these medically refractory patients is needed to ascertain whether these results are clinically significant

Adolescent externalizing behaviour, psychological control, and peer rejection: Transactional links and dopaminergic moderation.

Science.gov (United States)

Janssens, Annelies; Van Den Noortgate, Wim; Goossens, Luc; Verschueren, Karine; Colpin, Hilde; Claes, Stephan; Van Heel, Martijn; Van Leeuwen, Karla

2017-09-01

This study investigated (1) reciprocal links among parental psychological control, peer rejection, and adolescent externalizing (aggressive and rule-breaking behaviour), and (2) the moderating effect of an adolescent genetic factor (biologically informed polygenic score for dopamine signalling). Three-year longitudinal data from 1,116 adolescents (51% boys; M age = 13.79) and their parents included psychological measures (adolescent-reported psychological control, peer-reported rejection, and parent-reported aggressive and rule-breaking behaviour). Cross-lagged analyses showed bidirectional effects between psychological control and both aggressive and rule-breaking behaviour and a unidirectional effect of peer rejection on both forms of problem behaviour over time. Multigroup structural equation modelling revealed genetic moderation only for rule-breaking behaviour: for adolescents with intermediate levels of dopamine signalling significant environmental effects were present, whereas adolescent effects of rule-breaking behaviour on psychological control were significant for adolescents with both intermediate and high profiles and effects on peer rejection only for adolescents with high dopamine profiles. Statement of contribution What is already known on this subject? Parental psychological control is related to adolescent externalizing problems. Experiencing peer rejection reinforces aggressive and rule-breaking behaviour. Single-gene studies show that dopaminergic genes influence externalizing problems directly or in interaction with the environment. What does this study add? Parental psychological control and adolescent aggressive and rule-breaking behaviour exacerbate one another longitudinally. Longitudinal associations between peer rejection and both subtypes of externalizing behaviour are unidirectional. With a polygenic approach, dopaminergic moderation is present for rule-breaking behaviour only. © 2017 The British Psychological Society.

CD16+ Monocytes and Skewed Macrophage Polarization toward M2 Type Hallmark Heart Transplant Acute Cellular Rejection

OpenAIRE

van den Bosch, Thierry P. P.; Caliskan, Kadir; Kraaij, Marina D.; Constantinescu, Alina A.; Manintveld, Olivier C.; Leenen, Pieter J. M.; von der Th?sen, Jan H.; Clahsen-van Groningen, Marian C.; Baan, Carla C.; Rowshani, Ajda T.

2017-01-01

textabstractBackground: During acute heart transplant rejection, infiltration of lymphocytes and monocytes is followed by endothelial injury and eventually myocardial fibrosis. To date, no information is available on monocyte-macrophage-related cellular shifts and their polarization status during rejection. Here, we aimed to define and correlate monocyte-macrophage endomyocardial tissue profiles obtained at rejection and time points prior to rejection, with corresponding serial blood samples ...

Rejection of unfair offers can be driven by negative emotions, evidence from modified ultimatum games with anonymity.

Science.gov (United States)

Ma, Ning; Li, Nan; He, Xiao-Song; Sun, De-Lin; Zhang, Xiaochu; Zhang, Da-Ren

2012-01-01

The rejection of unfair offers can be affected by both negative emotions (e.g. anger and moral disgust) and deliberate cognitive processing of behavioral consequences (e.g. concerns of maintaining social fairness and protecting personal reputation). However, whether negative emotions are sufficient to motivate this behavior is still controversial. With modified ultimatum games, a recent study (Yamagishi T, et al. (2009) Proc Natl Acad Sci USA 106:11520-11523) found that people reject unfair offers even when this behavior increases inequity, and even when they could not communicate to the proposers. Yamagishi suggested that rejection of unfair offers could occur without people's concerning of maintaining social fairness, and could be driven by negative emotions. However, as anonymity was not sufficiently guaranteed in Yamagishi's study, the rejection rates in their experiments may have been influenced by people's concerns of protecting personal reputation (reputational concerns) in addition to negative emotions; thus, it was unclear whether the rejection was driven by negative emotions, or by reputational concerns, or both. In the present study, with specific methods to ensure anonymity, the effect of reputational concerns was successfully ruled out. We found that in a private situation in which rejection could not be driven by reputational concerns, the rejection rates of unfair offers were significantly larger than zero, and in public situations in which rejection rates could be influenced by both negative emotions and reputational concerns, rejection rates were significantly higher than that in the private situation. These results, together with Yamagishi's findings, provided more complete evidence suggesting (a) that the rejection of unfair offers can be driven by negative emotions and (b) that deliberate cognitive processing of the consequences of the behavior can increase the rejection rate, which may benefit social cooperation.

Disturbance rejection performance analyses of closed loop control systems by reference to disturbance ratio.

Science.gov (United States)

Alagoz, Baris Baykant; Deniz, Furkan Nur; Keles, Cemal; Tan, Nusret

2015-03-01

This study investigates disturbance rejection capacity of closed loop control systems by means of reference to disturbance ratio (RDR). The RDR analysis calculates the ratio of reference signal energy to disturbance signal energy at the system output and provides a quantitative evaluation of disturbance rejection performance of control systems on the bases of communication channel limitations. Essentially, RDR provides a straightforward analytical method for the comparison and improvement of implicit disturbance rejection capacity of closed loop control systems. Theoretical analyses demonstrate us that RDR of the negative feedback closed loop control systems are determined by energy spectral density of controller transfer function. In this manner, authors derived design criteria for specifications of disturbance rejection performances of PID and fractional order PID (FOPID) controller structures. RDR spectra are calculated for investigation of frequency dependence of disturbance rejection capacity and spectral RDR analyses are carried out for PID and FOPID controllers. For the validation of theoretical results, simulation examples are presented. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

Analysis of stray grain formation in single crystal CMSX-4 superalloy; Analyse der Bildung von Fehlkoernern in einer einkristallinen CMSX-4-Superlegierung

Energy Technology Data Exchange (ETDEWEB)

Chmiela, Bartosz; Sozanska, Maria; Cwajna, Jan [Silesian Univ. of Technology, Katowice (Poland). Dept. of Materials Science; Szeliga, Dariusz [Rzeszow Univ. of Technology (Poland). Dept. of Materials Science; Jarczyk, Jerzy [ALD Vacuum Technologies, Hanau (Germany)

2013-08-01

Modern single crystal (SX) turbine blades are fabricated by directional solidification using a grain selector. The grain selection process was investigated by numerical simulation and verified by the experiment. A coupled ProCAST and cellular automaton finite element (CAFE) model was used in this study. According to the latest literature data, we designed the grain selector. Simulation confirmed an optimal grain selection efficiency of the applied selector geometry. The obtained experimental results reveal the possibility of stray grain formation in SX castings with a designed selector, in contrast to the simulation results. (orig.)

Indwelling Stent Embedded with Light-Emitting Diodes for Photodynamic Therapy of Malignant Biliary Obstruction

International Nuclear Information System (INIS)

Baran, Timothy M.; Mironov, Oleg; Sharma, Ashwani K.; Foster, Thomas H.

2016-01-01

PurposeWe describe the design and preliminary characterization of a stent incorporating light-emitting diodes (LEDs) for photodynamic therapy (PDT) of malignant biliary obstruction.MethodsA prototype was constructed with red (640 nm) LEDs embedded in a 14.5 French polyurethane tube. The device was evaluated for optical power and subjected to physical and electrical tests. PDT-induced reactive oxygen species were imaged in a gel phantom.ResultsThe stent functioned at a 2.5-cm bend radius and illuminated for 6 months in saline. No stray currents were detected, and it was cool after 30 minutes of operation. Optical power of 5–15 mW is applicable to PDT. Imaging of a reactive oxygen indicator showed LED-stent activation of photosensitizer.ConclusionsThe results motivate biological testing and design optimization.

Indwelling Stent Embedded with Light-Emitting Diodes for Photodynamic Therapy of Malignant Biliary Obstruction

Energy Technology Data Exchange (ETDEWEB)

Baran, Timothy M., E-mail: timothy.baran@rochester.edu [University of Rochester Medical Center, Department of Imaging Sciences (United States); Mironov, Oleg, E-mail: oleg.mironov@uhn.ca [University Health Network, The Joint Department of Medical Imaging (Canada); Sharma, Ashwani K., E-mail: Ashwani-Sharma@URMC.Rochester.edu; Foster, Thomas H., E-mail: thomas.foster@rochester.edu [University of Rochester Medical Center, Department of Imaging Sciences (United States)

2016-06-15

PurposeWe describe the design and preliminary characterization of a stent incorporating light-emitting diodes (LEDs) for photodynamic therapy (PDT) of malignant biliary obstruction.MethodsA prototype was constructed with red (640 nm) LEDs embedded in a 14.5 French polyurethane tube. The device was evaluated for optical power and subjected to physical and electrical tests. PDT-induced reactive oxygen species were imaged in a gel phantom.ResultsThe stent functioned at a 2.5-cm bend radius and illuminated for 6 months in saline. No stray currents were detected, and it was cool after 30 minutes of operation. Optical power of 5–15 mW is applicable to PDT. Imaging of a reactive oxygen indicator showed LED-stent activation of photosensitizer.ConclusionsThe results motivate biological testing and design optimization.

Fauna of Zoontic Parasites of Stray Dogs in Yasouj Suburbs in 2008

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A Moshfe

2011-04-01

Full Text Available Introduction & Objective: Dogs are among the closest animals to human residents and can by useful for human. A few of zoontic diseases are prevalent in Iran. Dogs are the reservoirs of many of these zoonosis and a major role in transmission of infection. The aim of this study was to determine the zoonotic parasitic fauna of stray dogs in Yasuj Materials & Methods: In this descriptive study which was conducted at Yasuj suburbs in 2008, 25 dogs’ corpses were necropsied and their tissues were studied for parasitic infections. Collected parasites were placed in special containers and stained for genus and species diagnosis based on their morphological features. The collected data were analyzed with the SPSS software, using descriptive analysis. Results: Of the 25 studied corpses, 23 dogs were infected with at least one parasite. Helminthic infections of dogs were consisted of: Taenia hydatigena, Mesocestoides sp., Echinococcus granulosus, Dipylidium caninum, Macracanthorhynchus hirudinaceus and Spirocerca lupi. Conclusion: Four of six detected helminthes in in dogs in this study are zoonotic parasites which are important in human diseases. Among them larval stage of Echinococcus granulosus which causes hydatid cyst disease in human is very important. Control programs should be implemented in this region to prevent these zoonotic diseases.