WorldWideScience

Sample records for strategy basic research

  1. Transforming Defense Basic Research Strategy

    National Research Council Canada - National Science Library

    Fountain, Augustus W

    2004-01-01

    .... Public funding of basic research for the DoD during the Cold War was successful because it minimized risk through taking maximum advantage of long term research projects that produced rather mature...

  2. Transforming Defense Basic Research Strategy

    National Research Council Canada - National Science Library

    Fountain, Augustus W

    2004-01-01

    ... technologies for development. With a basic research budget less than half that of the National Science Foundation and a mere fraction that of the NIH the DoD can no longer afford to pursue lofty science education goals...

  3. Basic science and energy research sector profile: Background for the National Energy Strategy

    Energy Technology Data Exchange (ETDEWEB)

    March, F.; Ashton, W.B.; Kinzey, B.R.; McDonald, S.C.; Lee, V.E.

    1990-11-01

    This Profile report provides a general perspective on the role of basic science in the spectrum of research and development in the United States, and basic research's contributions to the goals of the National Energy Strategy (NES). It includes selected facts, figures, and analysis of strategic issues affecting the future of science in the United States. It is provided as background for people from government, the private sector, academia, and the public, who will be reviewing the NES in the coming months; and it is intended to serve as the basis for discussion of basic science issues within the context of the developing NES.

  4. Basic Research Firing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Basic Research Firing Facility is an indoor ballistic test facility that has recently transitioned from a customer-based facility to a dedicated basic research...

  5. Creative Management as a Strategy for Breakthrough Innovation. Lessons from Basic Research Projects of Japanese Companies.

    Science.gov (United States)

    Lee, K. T.

    1997-01-01

    Japanese science/technology policies emphasize creative research management for strengthening breakthrough innovation. Key lessons include the following: cultivation of creative researchers, clear strategic directions, systematic teamwork and collaboration, focus on strategic industrial relevance, balance between autonomy and control, and the need…

  6. Basic research projects

    International Nuclear Information System (INIS)

    1979-04-01

    The research programs under the cognizance of the Office of Energy Research (OER) are directed toward discovery of natural laws and new knowledge, and to improved understanding of the physical and biological sciences as related to the development, use, and control of energy. The ultimate goal is to develop a scientific underlay for the overall DOE effort and the fundamental principles of natural phenomena so that these phenomena may be understood, and new principles, formulated. The DOE-OER outlay activities include three major programs: High Energy Physics, Nuclear Physics, and Basic Energy Sciences. Taken together, these programs represent some 30 percent of the Nation's Federal support of basic research in the energy sciences. The research activities of OER involve more than 6,000 scientists and engineers working in some 17 major Federal Research Centers and at more than 135 different universities and industrial firms throughout the United States. Contract holders in the areas of high-energy physics, nuclear physics, materials sciences, nuclear science, chemical sciences, engineering, mathematics geosciences, advanced energy projects, and biological energy research are listed. Funding trends for recent years are outlined

  7. Reconfiguring the Role of the Research Paper: Collaborative Writing To Teach Basic Academic Research and Writing Strategies.

    Science.gov (United States)

    Fleming, Michelle M.

    Each year that the author of this paper, an English instructor at Moorhead College (Minnesota), teaches the first-year "research paper," one instructor turns more and more to collaborative writing work. And she admits that some of her motives in reshaping the research paper in collaborative ways can seem to be based in assisting herself…

  8. Basic Research Needs for Countering Terrorism

    Energy Technology Data Exchange (ETDEWEB)

    Stevens, W.; Michalske, T.; Trewhella, J.; Makowski, L.; Swanson, B.; Colson, S.; Hazen, T.; Roberto, F.; Franz, D.; Resnick, G.; Jacobson, S.; Valdez, J.; Gourley, P.; Tadros, M.; Sigman, M.; Sailor, M.; Ramsey, M.; Smith, B.; Shea, K.; Hrbek, J.; Rodacy, P.; Tevault, D.; Edelstein, N.; Beitz, J.; Burns, C.; Choppin, G.; Clark, S.; Dietz, M.; Rogers, R.; Traina, S.; Baldwin, D.; Thurnauer, M.; Hall, G.; Newman, L.; Miller, D.; Kung, H.; Parkin, D.; Shuh, D.; Shaw, H.; Terminello, L.; Meisel, D.; Blake, D.; Buchanan, M.; Roberto, J.; Colson, S.; Carling, R.; Samara, G.; Sasaki, D.; Pianetta, P.; Faison, B.; Thomassen, D.; Fryberger, T.; Kiernan, G.; Kreisler, M.; Morgan, L.; Hicks, J.; Dehmer, J.; Kerr, L.; Smith, B.; Mays, J.; Clark, S.

    2002-03-01

    To identify connections between technology needs for countering terrorism and underlying science issues and to recommend investment strategies to increase the impact of basic research on efforts to counter terrorism.

  9. Basic petroleum research. Final report

    International Nuclear Information System (INIS)

    Roesjoe, Bjarne; Stiksrud, Helge

    2004-01-01

    An overview of projects in the field of basic petroleum research (PetroForsk) is presented. A brief presentation of some of the projects is included, as well as political comments on the value of these projects. The research program Basic Petroleum Research (PetroForsk) was established in 1998 and ended in 2004. The program has been part of the Research Council of Norway's long-term effort in petroleum research (ml)

  10. Basic research for environmental restoration

    International Nuclear Information System (INIS)

    1990-12-01

    The Department of Energy (DOE) is in the midst of a major environmental restoration effort to reduce the health and environmental risks resulting from past waste management and disposal practices at DOE sites. This report describes research needs in environmental restoration and complements a previously published document, DOE/ER-0419, Evaluation of Mid-to-Long Term Basic Research for Environmental Restoration. Basic research needs have been grouped into five major categories patterned after those identified in DOE/ER-0419: (1) environmental transport and transformations; (2) advanced sampling, characterization, and monitoring methods; (3) new remediation technologies; (4) performance assessment; and (5) health and environmental effects. In addition to basic research, this document deals with education and training needs for environmental restoration. 2 figs., 6 tabs

  11. Basic research for environmental restoration

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-01

    The Department of Energy (DOE) is in the midst of a major environmental restoration effort to reduce the health and environmental risks resulting from past waste management and disposal practices at DOE sites. This report describes research needs in environmental restoration and complements a previously published document, DOE/ER-0419, Evaluation of Mid-to-Long Term Basic Research for Environmental Restoration. Basic research needs have been grouped into five major categories patterned after those identified in DOE/ER-0419: (1) environmental transport and transformations; (2) advanced sampling, characterization, and monitoring methods; (3) new remediation technologies; (4) performance assessment; and (5) health and environmental effects. In addition to basic research, this document deals with education and training needs for environmental restoration. 2 figs., 6 tabs.

  12. Basic statistics for social research

    CERN Document Server

    Hanneman, Robert A; Riddle, Mark D

    2012-01-01

    A core statistics text that emphasizes logical inquiry, notmath Basic Statistics for Social Research teaches core generalstatistical concepts and methods that all social science majorsmust master to understand (and do) social research. Its use ofmathematics and theory are deliberately limited, as the authorsfocus on the use of concepts and tools of statistics in theanalysis of social science data, rather than on the mathematicaland computational aspects. Research questions and applications aretaken from a wide variety of subfields in sociology, and eachchapter is organized arou

  13. Research into basic rocks types

    International Nuclear Information System (INIS)

    1993-06-01

    Teollisuuden Voima Oy (TVO) has carried out research into basic rock types in Finland. The research programme has been implemented in parallel with the preliminary site investigations for radioactive waste disposal in 1991-1993. The program contained two main objectives: firstly, to study the properties of the basic rock types and compare those with the other rock types under the investigation; secondly, to carry out an inventory of rock formations consisting of basic rock types and suitable in question for final disposal. A study of environmental factors important to know regarding the final disposal was made of formations identified. In total 159 formations exceeding the size of 4 km 2 were identified in the inventory. Of these formations 97 were intrusive igneous rock types and 62 originally extrusive volcanic rock types. Deposits consisting of ore minerals, industrial minerals or building stones related to these formations were studied. Environmental factors like natural resources, protected areas or potential for restrictions in land use were also studied

  14. Basic research on maxillofacial implants

    Energy Technology Data Exchange (ETDEWEB)

    Matsui, Yoshiro [Showa Univ., Tokyo (Japan). School of Dentistry

    2001-11-01

    Osseointegrated implants have begun to be used not only in general practice in dentistry but also in various clinical situations in the maxillofacial region. The process has yielded three problems: the spread of application, new materials and diagnostic methods, and management for difficult situations. This paper presents basic data and clinical guidelines for new applications, it investigates the characteristics of the materials and the usefulness of a new diagnostic method, and it studies effective techniques for difficult cases. The results obtained are as follows: Investigations into the spreading application. The lateral and superior orbital rim have sufficient bone thickness and width for the implant body to be placed. Osseointegrated implants, especially by the fixed bridge technique, are not recommended in the craniofacial bone and jaws of young children. Implant placement into bone after/before irradiation must be performed in consideration of impaired osteogenesis, the decrease of trabecular bone, and the time interval between implantation and irradiation. Investigations into materials and diagnostic methods. Hydroxyapatite-coated and titanium implants should be selected according to the characteristics of the materials. A dental simulating soft may also be applicable in the craniofacial region. Investigations into the management of difficult cases. Hyperbaric oxygen therapy (HBO), bone morphogenetic protein (BMP), and tissue engineering should be useful for improving the quality and increasing the quantity of bone where implants are placed. Soft tissue around implants placed in the reconstructed area should be replaced with mucosal tissue. The data obtained here should be useful for increasing the efficiency of osseointegrated implants, but further basic research is required in the future. (author)

  15. Basic research on maxillofacial implants

    International Nuclear Information System (INIS)

    Matsui, Yoshiro

    2001-01-01

    Osseointegrated implants have begun to be used not only in general practice in dentistry but also in various clinical situations in the maxillofacial region. The process has yielded three problems: the spread of application, new materials and diagnostic methods, and management for difficult situations. This paper presents basic data and clinical guidelines for new applications, it investigates the characteristics of the materials and the usefulness of a new diagnostic method, and it studies effective techniques for difficult cases. The results obtained are as follows: Investigations into the spreading application. The lateral and superior orbital rim have sufficient bone thickness and width for the implant body to be placed. Osseointegrated implants, especially by the fixed bridge technique, are not recommended in the craniofacial bone and jaws of young children. Implant placement into bone after/before irradiation must be performed in consideration of impaired osteogenesis, the decrease of trabecular bone, and the time interval between implantation and irradiation. Investigations into materials and diagnostic methods. Hydroxyapatite-coated and titanium implants should be selected according to the characteristics of the materials. A dental simulating soft may also be applicable in the craniofacial region. Investigations into the management of difficult cases. Hyperbaric oxygen therapy (HBO), bone morphogenetic protein (BMP), and tissue engineering should be useful for improving the quality and increasing the quantity of bone where implants are placed. Soft tissue around implants placed in the reconstructed area should be replaced with mucosal tissue. The data obtained here should be useful for increasing the efficiency of osseointegrated implants, but further basic research is required in the future. (author)

  16. Fiscal 1999 research report on long-term energy technology strategy. Basic research on industrial technology strategy (Individual technology strategy (Textile technology field)); 1999 nendo choki energy gijutsu senryku nado ni kansuru chosa hokokusho. Sangyo gijutsu senryaku sakutei kiban chosa (bun'yabetsu gijutsu senryaku (sen'i gijutsu bun'ya))

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This report summarizes the fiscal 1999 basic research result on industrial technology strategy of a textile technology field. Social demand and constraint in the 21st century restrict human life and industrial activity, however, include huge business chances. This technology strategy aims at construction of textile business contributing to the society, and improvement of the international competitiveness of Japanese textile industry. Analysis was made on the current international competitiveness of the textile industry in comparison between Japanese and American productivity. As factors hindering technological innovation, the following were pointed out: poor cooperation among industry, academia and government, poor cooperation among different kinds of industries, poor preparation of basic technology, knowledge base and creation base, and poor deregulation. As the future target and strategy, 7 technology targets, 2 creation targets, and every target year were showed. 4 proposals were also showed as follows: preparation of a technology base, creation base, talent education and knowledge base, and protection of intellectual property rights. (NEDO)

  17. National Privacy Research Strategy

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — On July 1, NITRD released the National Privacy Research Strategy. Research agencies across government participated in the development of the strategy, reviewing...

  18. 32 CFR 37.1240 - Basic research.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Basic research. 37.1240 Section 37.1240 National... TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1240 Basic research. Efforts... practical application of that knowledge and understanding. It typically is funded within Research...

  19. Action Research: Some basic issues

    DEFF Research Database (Denmark)

    Rasmussen, Lauge Baungaard

    2003-01-01

    The article introduces the main characteristica of action research as well as its origin. In addition the epistmological criteria are presented and discussed. Finally power relationships and ethical concerns are reflected in relation to the practice of action research.......The article introduces the main characteristica of action research as well as its origin. In addition the epistmological criteria are presented and discussed. Finally power relationships and ethical concerns are reflected in relation to the practice of action research....

  20. Biomechanics: basic and applied research

    International Nuclear Information System (INIS)

    Bergmann, G.; Rohlmann, A.; Koelbel, R.

    1987-01-01

    This volume presents the state of the art in biomechanics. The most recent achievements of biomechanical research in the fields of orthopaedics, dynamics of the musculoskeletal system, hard and soft tissues, rehabilitation, sports, cardiovascular problems and research methodology have been selected and edited by a distinguished panel of reviewers. The material is such that the volume will serve as a reference for many years for bioengineers, sports scientists, clinicians and clinical researchers in rehabilitation, orthopaedics and cardiovascular surgery

  1. Defending basic research in Europe

    CERN Multimedia

    Staff Association

    2010-01-01

    « Research without a budget means a Europe without a future » On Wednesday 25th August 2010, 871 of you signed the Staff Council petition which carried this message. This is a resounding success for a month of August. Staff members and pensioners, you showed by your presence your mass support for our appeal to defend research budgets in Europe. The participation and messages of support from our colleagues in other European scientific organizations is confirmation that budget cuts in research are common practice far beyond the confines of CERN. If research had benefited from the promises made by the European Union in 2000 to increase investment in research and development (R&D) from 1.8% to 3% of GDP by 2010, the scientific community would more readily accept the current cuts. However, we are now in 2010 and the rate of 1.8% has remained the same. So, we have been hit twice: not only have we not had the good weather we were promised, we now find ourselves in the middl...

  2. Basic Research in the United States.

    Science.gov (United States)

    Handler, Philip

    1979-01-01

    Presents a discussion of the development of basic research in the U.S. since World War II. Topics include the creation of the federal agencies, physics and astronomy, chemistry, earth science, life science, the environment, and social science. (BB)

  3. Basic science research in urology training.

    Science.gov (United States)

    Eberli, D; Atala, A

    2009-04-01

    The role of basic science exposure during urology training is a timely topic that is relevant to urologic health and to the training of new physician scientists. Today, researchers are needed for the advancement of this specialty, and involvement in basic research will foster understanding of basic scientific concepts and the development of critical thinking skills, which will, in turn, improve clinical performance. If research education is not included in urology training, future urologists may not be as likely to contribute to scientific discoveries.Currently, only a minority of urologists in training are currently exposed to significant research experience. In addition, the number of physician-scientists in urology has been decreasing over the last two decades, as fewer physicians are willing to undertake a career in academics and perform basic research. However, to ensure that the field of urology is driving forward and bringing novel techniques to patients, it is clear that more research-trained urologists are needed. In this article we will analyse the current status of basic research in urology training and discuss the importance of and obstacles to successful addition of research into the medical training curricula. Further, we will highlight different opportunities for trainees to obtain significant research exposure in urology.

  4. Basic science research in urology training

    Directory of Open Access Journals (Sweden)

    D Eberli

    2009-01-01

    In this article we will analyse the current status of basic research in urology training and discuss the importance of and obstacles to successful addition of research into the medical training curricula. Further, we will highlight different opportunities for trainees to obtain significant research exposure in urology.

  5. Fiscal 1999 research report on long-term energy technology strategy. Basic research on industrial technology strategy (Individual technology strategy). Iron and steel technology field; 1999 nendo choki energy gijutsu senryaku nado ni kansuru chosa hokokusho. Sangyo gijutsu senryaku sakutei kiban chosa (bun'yabetsu gijutsu senryaku) (tekko gijutsu bun'ya)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This report summarizes the fiscal 1999 basic research result on industrial technology strategy of a steel technology field. Japanese steel industry should correspond to requirements of the international economic society as the top runner. Although it is now difficult to suppose a basic technology innovation, stable supply of basic materials is necessary for peripheral industries. The basic raw material technology is the basis of domestic and overseas socio- economic activities. The technology development support system to retain the world-wide leadership of Japanese industries is a strategic issue. Preparation of cooperative R and D bases of industry, academia and government along a national policy is important. Strong promotion of such national projects is also essential as global environment problem, positive use of advanced information tools, development of technologies and products of unexplored fields, and development of new products and demand creation according to social needs. Such measures along social requirements are also important as raw material development to double an energy efficiency, and the policy and system to construct a recycling society and living spaces. (NEDO)

  6. Basic Energy Sciences FY 2012 Research Summaries

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-01-01

    This report provides a collection of research abstracts and highlights for more than 1,400 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2012 at some 180 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  7. Basic Energy Sciences FY 2014 Research Summaries

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-01-01

    This report provides a collection of research abstracts and highlights for more than 1,200 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2014 at some 200 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  8. Basic Energy Sciences FY 2011 Research Summaries

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-01-01

    This report provides a collection of research abstracts for more than 1,300 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2011 at some 180 institutions across the U.S. This volume is organized along the three BES divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  9. Fiscal 1999 research report. Research on the long-term energy technology strategy (Basic research on the industrial technology strategy (Material technology field)); 1999 nendo choki energy gijutsu senryaku nado ni kansuru chosa hokokusho. Sangyo gijutsu senryaku sakutei kiban chosa (bun'yabetsu gijutsu senryaku (zairyo gijutsu bun'ya))

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This research clarifies the future social issues and targets of industrial technology in a material field including metal, inorganic, organic, polymer and fiber materials, and proposes the strategy for achieving such targets, based on research on changes in science and technology trend (technical innovation), and analysis on present and future industrial and technical competition powers. The future basic technologies for enhancing such competition powers are as follows: (1) Resource/energy-saving production process, (2) Design/evaluation technology for fine textures or in an atomic level, (3) Divergence toward high-purity and composite materials, (4) Improvement of a functionality, (5) Improvement of surface treatment technologies, and (6) Development of new materials and production technologies by using computer. The following 5 strategies are proposed based on the common understanding that the Japanese material industry achieves the best material technology innovation in the world by 2010: (1) Material technology strategy, (2) Strong cooperation among the industry, university and government, (3) Preparation of an intellectual base and a standardization strategy, (4) Reform of intellectual property rights, and (5) Resource strategy. (NEDO)

  10. Fiscal 1999 research report. Research on the long-term energy technology strategy (Basic research on the industrial technology strategy (Material technology field)); 1999 nendo choki energy gijutsu senryaku nado ni kansuru chosa hokokusho. Sangyo gijutsu senryaku sakutei kiban chosa (bun'yabetsu gijutsu senryaku (zairyo gijutsu bun'ya))

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This research clarifies the future social issues and targets of industrial technology in a material field including metal, inorganic, organic, polymer and fiber materials, and proposes the strategy for achieving such targets, based on research on changes in science and technology trend (technical innovation), and analysis on present and future industrial and technical competition powers. The future basic technologies for enhancing such competition powers are as follows: (1) Resource/energy-saving production process, (2) Design/evaluation technology for fine textures or in an atomic level, (3) Divergence toward high-purity and composite materials, (4) Improvement of a functionality, (5) Improvement of surface treatment technologies, and (6) Development of new materials and production technologies by using computer. The following 5 strategies are proposed based on the common understanding that the Japanese material industry achieves the best material technology innovation in the world by 2010: (1) Material technology strategy, (2) Strong cooperation among the industry, university and government, (3) Preparation of an intellectual base and a standardization strategy, (4) Reform of intellectual property rights, and (5) Resource strategy. (NEDO)

  11. [Basic research in ophthalmology in Germany and its international context].

    Science.gov (United States)

    Schlötzer-Schrehardt, U; Cursiefen, C

    2017-09-01

    Experimental basic research provides the foundations for the elucidation of pathophysiological mechanisms of diseases and the development of novel diagnostic and therapeutic strategies for ophthalmological diseases. The objective of this contribution is to provide an overview of the international interconnection of basic research in ophthalmology in Germany. The international context of ophthalmological research conducted in Germany is presented by means of personal experiences and data published by the German Ophthalmological Society (DOG), the German Research Foundation (DFG) and the European Union (EU). Due to the lack of organized databases this article lays no claim to completeness. Basic research in ophthalmology in Germany is mainly conducted in university eye departments and is mainly related to the etiology, pathophysiology and therapy development for various ophthalmic diseases. It is primarily funded by the DFG, the Federal Ministry of Education and Research (BMBF) and the EU plays an increasingly important role. Thus, ophthalmological research is integrated into numerous European research networks and beyond that into many international interconnections and relationships. In Germany, both clinical and basic research in ophthalmology is integrated into many international networks and is only functionally viable in an international context; however, given the increasing impact of ophthalmological research in Asian countries, future strategies require a continued focus on career development, research infrastructure, working environment and international cooperation.

  12. Peer review, basic research, and engineering: Defining a role for QA professionals in basic research environments

    Energy Technology Data Exchange (ETDEWEB)

    Bodnarczuk, M.

    1989-02-01

    Within the context of doing basic research, this paper seeks to answer four major questions: (1) What is the authority structure of science. (2) What is peer review. (3) Where is the interface between basic physics research and standard engineering. and (4) Given the conclusions to the first three questions, what is the role of the QA professional in a basic research environment like Fermilab. 23 refs.

  13. AECL programs in basic physics research

    International Nuclear Information System (INIS)

    Bartholomew, G.A.; Dolling, G.; Harvey, M.; Milton, J.C.D.

    1982-02-01

    This report describes the CRNL program of research into the basic properties of atomic nuclei and condensed matter (liquids and solids). Brief descriptions are given of some of the current experimental programs done principally at the NRU reactor and MP tandem accelerator, the associated theoretical studies, and some highlights of past achievements

  14. Calls for Canada to support basic research

    Science.gov (United States)

    Gwynne, Peter

    2017-08-01

    Canada’s decade-long shift of financial support from fundamental studies towards applied research is dismantling the nation’s funding of basic science, according to a report by the Global Young Academy (GYA) - an international society of young scientists.

  15. Fiscal 1999 research report on long-term energy technology strategy. Basic research on industrial technology strategy (Individual technology strategy). Machine industry technology field (Machine tool); 1999 nendo choki energy gijutsu senryaku nado ni kansuru chosa hokokusho. Sangyo gijutsu senryaku sakutei kiban chosa (bun'yabetsu gijjtsu senryaku) kikai sangyo gijutsu bun'ya (kosaku kikai bun'ya)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This report summarizes the fiscal 1999 basic research result on industrial technology strategy of a machine tool field. Corresponding to construction of an environment-friendly recycling economic society and economic growth as estimated change in social and industrial structure during 2010-2025, major themes are reuse of machine tools, energy saving, environment design, chip treatment and resource recovery. With preparation of information infrastructures in an advanced information society, major issues are 3D-CAD, remote diagnosis, remote control and self-restoration. Because of decline of the birth rate, positive employment of aged persons and women is desirable. New machining technology for new materials, and fusion of various machining technologies are important. For micro-technology, study should be made on the concept and effect of micro-factory (energy saving, space saving, cost reduction, higher accuracy and higher speed). For higher-accuracy machine tool, static, dynamic, thermal and movement characteristics are the key for improving the proper technology. For faster machining. fine basic structural element, faster main spindle and faster feed are important. (NEDO)

  16. Blackjack in Holland Casino's : Basic, optimal and winning strategies

    NARCIS (Netherlands)

    van der Genugten, B.B.

    1995-01-01

    This paper considers the cardgame Blackjack according to the rules of Holland Casino's in the Netherlands. Expected gains of strategies are derived with simulation and also with analytic tools. New effiency concepts based on the gains of the basic and the optimal strategy are introduced. A general

  17. Denmark lacks coherent policy on basic research

    DEFF Research Database (Denmark)

    Ibba, Michael; Bentin, Thomas

    1999-01-01

    suggest that more critical problems exist that must be addressed immediately to ensure the long-term health of Danish science. Chief among these are a poorly funded and misdirected policy on basic research funding, and conditions of employment that restrict the research opportunities of young scientists...... unattractive, with limited long-term prospects. This situation is only alleviated by the benefaction of senior scientists and charitable foundations, and occasional directives in selected areas which allow young scientists to develop independent research. Further obstacles exist in the recruitment process: new...... positions are often focused on narrow research areas and only advertised locally (in Danish). Recent well-intentioned legislative changes have not fully addressed these problems. Such an inflexible system (which often obliges scientists to spend their entire career in the same institute) is ill...

  18. Fiscal 1999 research report on long-term energy technology strategy. Basic research on industrial technology strategy (Individual technology strategy). Aerospace technology field (Aircraft technology field); 1999 nendo choki energy gijutsu senryaku nado ni kansuru chosa hokokusho. Sangyo gijutsu senryaku sakutei kiban chosa (bun'yabetsu gijutsu senryaku (kokuki gijutsu bun'ya))

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This report summarizes the fiscal 1999 basic research result on industrial technology strategy of an aircraft technology field. In an aircraft field, since the major theme is application of new technologies to new airframe development, with joining in international cooperative development of aircraft, Japanese initiative development of airframes based on the domestic market demands and profitability should be started as early as possible. Because there is no airframe development by only one country including U.S.A., Japan is profitable to unite with some overseas companies, and invest selectively in specific leading fields. Positive technical support to safety, reliability, comfort and environment harmony are also important. More important theme than establishment of elementary technologies is preparation of an integrated flight demonstration system to expand application chances of development results, and preparation of various test facilities for tests required during development activities. Application of information technologies to the whole aircraft industry, and organic cooperation between the private and public sectors are also important. (NEDO)

  19. Fiscal 1999 research report on long-term energy technology strategy. Basic research on industrial technology strategy (Individual technology strategy). Machine industry technology field (Semiconductor equipment); 1999 nendo choki energy gijutsu senryaku nado ni kansuru chosa hokokusho. Sangyo gijutsu senryaku sakutei kiban chosa (bun'yabetsu gijutsu senryaku) kikai sangyo gijutsu bun'ya (handotai seizo sochi bun'ya)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This report summarizes the fiscal 1999 basic research result on industrial technology strategy of a semiconductor equipment field, viewing until 5-10 years after. For the future semiconductor industry, the favorable cycling of creation of new demands through performance improvement, and further technology innovation through market expansion is essential absolutely. Since technology development is followed by investment, not only the performance of each equipment but also the higher productivity and cost balance of the whole factory are essential. Self-intelligent function and networking are thus necessary for the equipment. As measures for environment preservation and energy saving, such innovative technologies are required as recycling, reuse, reaction process improvement and alternative technology. Because of diverse final products and a short life time of products, a large-scale collective investment is becoming difficult. A mini-line sequential investment production system according to demand scales is under investigation. Some issues such as micro-technology, realization of 300mm wafer, modularization, CIM, reliability and standardization are also described. (NEDO)

  20. Basic Science Research and the Protection of Human Research Participants

    Science.gov (United States)

    Eiseman, Elisa

    2001-03-01

    Technological advances in basic biological research have been instrumental in recent biomedical discoveries, such as in the understanding and treatment of cancer, HIV/AIDS, and heart disease. However, many of these advances also raise several new ethical challenges. For example, genetic research may pose no physical risk beyond that of obtaining the initial blood sample, yet it can pose significant psychological and economic risks to research participants, such as stigmatization, discrimination in insurance and employment, invasion of privacy, or breach of confidentiality. These harms may occur even when investigators do not directly interact with the person whose DNA they are studying. Moreover, this type of basic research also raises broader questions, such as what is the definition of a human subject, and what kinds of expertise do Institutional Review Boards (IRBs) need to review the increasingly diverse types of research made possible by these advances in technology. The National Bioethics Advisory Commission (NBAC), a presidentially appointed federal advisory committee, has addressed these and other ethical, scientific and policy issues that arise in basic science research involving human participants. Two of its six reports, in particular, have proposed recommendations in this regard. "Research Involving Human Biological Materials: Ethical and Policy Guidance" addresses the basic research use of human tissues, cells and DNA and the protection of human participants in this type of research. In "Ethical and Policy Issues in the Oversight of Human Research" NBAC proposes a definition of research involving human participants that would apply to all scientific disciplines, including physical, biological, and social sciences, as well as the humanities and related professions, such as business and law. Both of these reports make it clear that the protection of research participants is key to conducting ethically sound research. By ensuring that all participants in

  1. Basic Research Tools for Earthworm Ecology

    Directory of Open Access Journals (Sweden)

    Kevin R. Butt

    2010-01-01

    Full Text Available Earthworms are responsible for soil development, recycling organic matter and form a vital component within many food webs. For these and other reasons earthworms are worthy of investigation. Many technologically-enhanced approaches have been used within earthworm-focused research. These have their place, may be a development of existing practices or bring techniques from other fields. Nevertheless, let us not overlook the fact that much can still be learned through utilisation of more basic approaches which have been used for some time. New does not always equate to better. Information on community composition within an area and specific population densities can be learned using simple collection techniques, and burrowing behaviour can be determined from pits, resin-insertion or simple mesocosms. Life history studies can be achieved through maintenance of relatively simple cultures. Behavioural observations can be undertaken by direct observation or with low cost webcam usage. Applied aspects of earthworm research can also be achieved through use of simple techniques to enhance population development and even population dynamics can be directly addressed with use of relatively inexpensive, effective marking techniques. This paper seeks to demonstrate that good quality research in this sphere can result from appropriate application of relatively simple research tools.

  2. Basic Research Tools for Earthworm Ecology

    International Nuclear Information System (INIS)

    Butt, K.R.; Grigoropoulou, N.

    2010-01-01

    Earthworms are responsible for soil development, recycling organic matter and form a vital component within many food webs. For these and other reasons earthworms are worthy of investigation. Many technologically-enhanced approaches have been used within earthworm-focused research. These have their place, may be a development of existing practices or bring techniques from other fields. Nevertheless, let us not overlook the fact that much can still be learned through utilisation of more basic approaches which have been used for some time. New does not always equate to better. Information on community composition within an area and specific population densities can be learned using simple collection techniques, and burrowing behaviour can be determined from pits, resin-insertion or simple mesocosms. Life history studies can be achieved through maintenance of relatively simple cultures. Behavioural observations can be undertaken by direct observation or with low cost we became usage. Applied aspects of earthworm research can also be achieved through use of simple techniques to enhance population development and even population dynamics can be directly addressed with use of relatively inexpensive, effective marking techniques. This paper seeks to demonstrate that good quality research in this sphere can result from appropriate application of relatively simple research tools.

  3. Alternatives to animal experimentation in basic research.

    Science.gov (United States)

    Gruber, Franz P; Hartung, Thomas

    2004-01-01

    In contrast to animal testing required by law to guarantee minimum safety standards for the licensing of drugs and chemicals, there are no regulations in basic research forcing scientists to perform animal tests. By (usually) free choice, questions are posed and hypotheses are examined which, in many cases, can only be answered by means of animal tests. Just as easily, different questions could be asked or different hypotheses could be examined which do not require animal tests. The only criterion for the choice of a topic is its relevance which cannot necessarily be judged in the short-term. Thus, it is up to the individual scientist to judge what is worth studying and therefore worth animal consumption. The educated mind will consider ethical aspects of this choice. However, on the other hand, this decision is largely influenced by questions of efficacy or (in a negative sense) by the obstacles posed to an animal consuming approach. Here, peer review and general attitude will strongly influence the methodology chosen. Availability and awareness of adequate in vitro techniques represent the prerequisites for the use of alternative methods. The least one can do in basic research is to avoid tests which cause severe suffering to animals, as is required in Switzerland and other European countries by binding ethical principles and guidelines. The increasing standard of approval and control procedures has improved the situation over the years. There are many examples of successful alternative methods in basic research. But, the application of such methods is in most cases limited to the laboratories in which they were developed, calling for technology transfer. Exceptions are procedures that are used worldwide, like the production of monoclonal antibodies, which instead of using the ascites mouse can also be performed in vitro with some good will. In these cases, commercialisation of the techniques has aided their spread within the scientific community. Sadly, many

  4. Rare earths: harvesting basic research for technology

    International Nuclear Information System (INIS)

    Jagatap, B.N.

    2014-01-01

    In recent years, rare earths are increasingly becoming a versatile platform for basic research that presents enormous technological potentials. A variety of nano-sized inorganic matrices varying from oxides, phosphates, gallates and aluminates, tungstates, stannates, vanadates to fluorides doped with different lanthanide ions have been synthesized and their optical properties have been investigated in the Chemistry Group, BARC. Another interesting application is laser cooling of solids using rare earth doped glasses with potential applications in remote cooling of electronic devices. Combining the luminescence properties of rare earths with photonic crystals is yet another potent area with wide ranging applications. In this presentation we provide an overview of these developments with examples from the R and D programs of the Chemistry Group, BARC

  5. Spicing Up Basic Science Instruction with Storyline Strategy; What Is ...

    African Journals Online (AJOL)

    This study determined the effect of storyline strategy on primary school pupils‟ achievement in Basic Science with moderating effect of English Language proficiency of pupils. This study is the pre-test, post-test control group. It is a 2 x 2 quasi experimental study in which intact classes were used. This implies that the design ...

  6. Decision Strategy Research

    Energy Technology Data Exchange (ETDEWEB)

    Hardeman, F

    2001-04-01

    The objective of SCK-CEN's R and D programme on decision strategies is: (1) to study the decision-making process in a nuclear context with particular emphasis on emergency preparedness; (2) to disseminate knowledge on nuclear emergency preparedness including courses in the field of off-site emergency response to nuclear accidents; (3) to co-ordinate efforts within SCK-CEN in the field of medical applications of radiation; (4) to support projects and reflexion groups related to interdisciplinary research on the no-technical aspects of radiation protection or nuclear apllications; (5) to give advice and support to authorities and the industry on any topic related to radiation protection and to make expertise and infrastructure available. Main focus of the programme is on the surveillance of the territory and emergency preparedness. Principal achievements in 2000 are described.

  7. Decision Strategy Research

    International Nuclear Information System (INIS)

    Hardeman, F.

    2001-01-01

    The objective of SCK-CEN's R and D programme on decision strategies is: (1) to study the decision-making process in a nuclear context with particular emphasis on emergency preparedness; (2) to disseminate knowledge on nuclear emergency preparedness including courses in the field of off-site emergency response to nuclear accidents; (3) to co-ordinate efforts within SCK-CEN in the field of medical applications of radiation; (4) to support projects and reflexion groups related to interdisciplinary research on the no-technical aspects of radiation protection or nuclear apllications; (5) to give advice and support to authorities and the industry on any topic related to radiation protection and to make expertise and infrastructure available. Main focus of the programme is on the surveillance of the territory and emergency preparedness. Principal achievements in 2000 are described

  8. SKI's research strategy

    International Nuclear Information System (INIS)

    2002-01-01

    to maintain undergraduate and postgraduate programmes within areas that are unique to nuclear safety. These activities are subject to time limited agreements and are regularly re-evaluated. The most recent agreement is from 2002 and entails a broadening of previous agreements. SKI judges that support must continue to be provided in these areas in the future. With the current scope of the aid, SKI judges that educational resources will be adequate within the foreseeable future. The competence situation must be constantly monitored, however, and initiatives taken in time to secure sufficient competence and capacity for the safety work. SKI's assessment is that the current research level must be maintained in the future in order to provide adequate support to supervision and competence provision. It is, however, extremely important that the research allocation have greater flexibility than the operating allocation. Experience has shown that a guaranteed allocation saving of 3% of last year's allocation is insufficient and that it is in the nature of research that there is greater variation than in the operating allocation. If the need for support to the universities should increase, this must not be at the expense of the resources used to support supervision. Such financing must be solved in some other way. The basic principle should be that universities and institutes of technology should finance their own undergraduate programmes. In the event of a decision to participate in CoEs and other international networks and research projects, SKI considers additional research funding to be necessary. SKI intends to get back in this matter when the international discussions regarding additional networks and projects have come further

  9. Improving basic math skills through integrated dynamic representation strategies.

    Science.gov (United States)

    González-Castro, Paloma; Cueli, Marisol; Cabeza, Lourdes; Álvarez-García, David; Rodríguez, Celestino

    2014-01-01

    In this paper, we analyze the effectiveness of the Integrated Dynamic Representation strategy (IDR) to develop basic math skills. The study involved 72 students, aged between 6 and 8 years. We compared the development of informal basic skills (numbers, comparison, informal calculation, and informal concepts) and formal (conventionalisms, number facts, formal calculus, and formal concepts) in an experimental group (n = 35) where we applied the IDR strategy and in a Control group (n = 37) in order to identify the impact of the procedure. The experimental group improved significantly in all variables except for number facts and formal calculus. It can therefore be concluded that IDR favors the development of the skills more closely related to applied mathematics than those related to automatic mathematics and mental arithmetic.

  10. Basic and technical research on lung cancer

    International Nuclear Information System (INIS)

    Miyamoto, Tadaaki

    2004-01-01

    In association with clinical study of carbon beam therapy for lung cancer, the basic research for lung cancer and the patients with this disease has been carried out for the past 10 years. With regard to lung damage by the carbon beams, firstly pulmonary function was measured and analyzed for the patients with stage I non-small cell lung cancer. Force expiratory volume in 1 second (FVE 1.0) and TLC (total lung capacity) was found to be reduced significantly at 6 and 12 months after therapy but the reduction rate was a little, which can support the safety of this treatment modality. Secondly, the regional lung damage by the beams was investigated by using correct fusion of CT images with carbon beam dose distribution, diagnostic follow-up CT images and blood flow and ventilation spect images. It demonstrated the graded decrease blood flow by dose and the compensatory increase of blood flow in the adjacent lobe of lung unexposed to irradiation. On the other hand, the biological study of carbon beam effects on lung cancer cells and tumors line was conducted. Firstly, by using 7 or 4 human lung cancer cell line, the radiosensitivity of carbon beams was compared with that of photons by different histological patterns. It was found that there was no essential difference in the sensitivity pattern for lung cancer histology between the carbon beams and photons though the former doubled the later in power. Secondly, by using IA cell lines among them, the dynamic of clonogenic cells (clonogen) in a nude tumor and the changes in its morphology following irradiation was investigated, clarifying that the clonogen proliferating under anoxic or hypoxic conditions played a pivotal role for tumor regrowth and stemmed from the different clone which had been genetically selected and developed under these conditions. The finding of clonogen becomes one of the evidence supporting the superiority of a single-dose radiotherapy to fractionated radiotherapy. (author)

  11. Focus on Basics: Connecting Research & Practice. Volume 7, Issue D

    Science.gov (United States)

    Garner, Barbara, Ed.

    2005-01-01

    "Focus on Basics" is the quarterly publication of the National Center for the Study of Adult Learning and Literacy. It presents best practices, current research on adult learning and literacy, and how research is used by adult basic education teachers, counselors, program administrators, and policymakers. "Focus on Basics" is…

  12. The Relationship between Basic and Applied Research in Universities

    Science.gov (United States)

    Bentley, Peter James; Gulbrandsen, Magnus; Kyvik, Svein

    2015-01-01

    What is the central research activity in modern universities? This paper uses a comprehensive survey among individuals from 15 countries to map differences in orientation towards basic/fundamental research, applied/practical research and a combination of the two. Despite some claims in the literature that basic research is no longer a…

  13. Safety research basic plan of JNC

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Japan Nuclear Cycle Development Institute (JNC) formally succeeded to Power Reactor and Nuclear Fuel Development Corporation (PNC) on October, 1 1998. This report describes the basic plan for major program of JNC which consists of two parts: management philosophy of the new institute and the latest revised medium term program. In the first part, the primary mission of JNC is to perform its R and D concentrating on fast breeder reactor and its fuel cycle, and treatment and disposal of high-level radioactive wastes, while at the same time giving special consideration to safety. In the second, individual programs in the new basic plan are discussed in detail. The outline and schedule of each program are also attached in the table form. (H. Itami)

  14. Basic research on cancer related to radiation associated medical researches

    International Nuclear Information System (INIS)

    Lee, Jong In; Hwang, Dae Yong; Bang, Ho Yoon

    2000-12-01

    Basic Research on Cancer related to Radiation Associated Medical Researches including 1. Establishment of animal model of colorectal cancer liver metastasis and measurement of angiogenesis, 2. Tissue expression of Tie-1 and Tie-2 in human colorectal cancer, 3. Enhancement of G2/Mphase Cell Fraction by Adenovirus-mediated p53 Gene Transfer in Ovarian Cancer Cell Lines, 4. Clinical Characteristics of the patients with Non-B Non-C Hepatocellular Carcinoma and Frequency of HBV, HCV and TTV Viremia in these Patients, 5. Significance of serum iron and ferritin in patients with stomach cancer, 6. Telomerase assay for early detection of lung cancer, 7. Study on the Usefulness of Aldehyde dehydrogenase-2 Genotyping for Risk Group of Alcohol-related Cancer Screening, 8. Gene therapy using hepatoma specific promoter, 9. Study on the Influence of DNA repair gene, XRCC1 Genotypes on the Risk of Head and Neck Cancer were performed

  15. Basic research on cancer related to radiation associated medical researches

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong In; Hwang, Dae Yong; Bang, Ho Yoon [and others

    2000-12-01

    Basic Research on Cancer related to Radiation Associated Medical Researches including 1. Establishment of animal model of colorectal cancer liver metastasis and measurement of angiogenesis, 2. Tissue expression of Tie-1 and Tie-2 in human colorectal cancer, 3. Enhancement of G2/Mphase Cell Fraction by Adenovirus-mediated p53 Gene Transfer in Ovarian Cancer Cell Lines, 4. Clinical Characteristics of the patients with Non-B Non-C Hepatocellular Carcinoma and Frequency of HBV, HCV and TTV Viremia in these Patients, 5. Significance of serum iron and ferritin in patients with stomach cancer, 6. Telomerase assay for early detection of lung cancer, 7. Study on the Usefulness of Aldehyde dehydrogenase-2 Genotyping for Risk Group of Alcohol-related Cancer Screening, 8. Gene therapy using hepatoma specific promoter, 9. Study on the Influence of DNA repair gene, XRCC1 Genotypes on the Risk of Head and Neck Cancer were performed.

  16. Fiscal 1999 research report on long-term energy technology strategy. Basic research on industrial technology strategy (Individual technology strategy). Electronic information technology field (Human process ware field for computers); 1999 nendo choki energy gijutsu senryaku nado ni kansuru chsao hokokusho. Sangyo gijutsu senryaku sakutei kiban chosa (bun'yabetsu gijutsu senryaku) denshi joho gijutsu bun'ya (computer kanren bun'ya no uchi, human process wear bun'ya)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This report summarizes the fiscal 1999 basic research result on industrial technology strategy of a human process ware (HPW) field on electronic information. Although the current HPW industry is not yet complete, various technologies concerned are being stored, and the HPW industry is expected as new major industry for home and personal information equipment. As factors hindering technological innovation in Japan, the incomplete market, poor cooperation between industry and government, ambiguous role of university, and poor standardization were pointed out. Technology trends were analyzed to extract seed technology fields from 3 viewpoints of mobile HPW available at any time, at any place and to anybody, HPW system capable of customizing every personal use, and HPW supporting development of a creativity. As general strategy, the technology seed chart and map of technical development targets for every HPW were prepared to conceive a route to practical use, and develop element technologies required for practical use, based on the future trend of the market. (NEDO)

  17. Fiscal 1999 research report on long-term energy technology strategy. Basic research on industrial technology strategy (Individual technology strategy). Electronic information technology field (Human process ware field for computers); 1999 nendo choki energy gijutsu senryaku nado ni kansuru chsao hokokusho. Sangyo gijutsu senryaku sakutei kiban chosa (bun'yabetsu gijutsu senryaku) denshi joho gijutsu bun'ya (computer kanren bun'ya no uchi, human process wear bun'ya)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This report summarizes the fiscal 1999 basic research result on industrial technology strategy of a human process ware (HPW) field on electronic information. Although the current HPW industry is not yet complete, various technologies concerned are being stored, and the HPW industry is expected as new major industry for home and personal information equipment. As factors hindering technological innovation in Japan, the incomplete market, poor cooperation between industry and government, ambiguous role of university, and poor standardization were pointed out. Technology trends were analyzed to extract seed technology fields from 3 viewpoints of mobile HPW available at any time, at any place and to anybody, HPW system capable of customizing every personal use, and HPW supporting development of a creativity. As general strategy, the technology seed chart and map of technical development targets for every HPW were prepared to conceive a route to practical use, and develop element technologies required for practical use, based on the future trend of the market. (NEDO)

  18. Fiscal 1999 research report on long-term energy technology strategy. Pt. 2. Basic research on industrial technology strategy (Individual technology strategy.) Material technology field (Fine ceramics); 1999 nendo choki energy gijutsu senryaku nado ni kansuru chosa hokokusho. 2. Sangyo gijutsu senryaku sakutei kiban chosa (bun'ya betsu gijutsu senryaku) zairyo gijutsu bun'ya (fine ceramics gijutsu bun'ya)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This report summarizes the basic research result on industrial technology strategy for a glass field. Japan is facing such various economic problems as attack by developing countries, collapse of economic babble and yen's appreciation, and environment problems over a period of several years, and a glass industry is also under the influence of such problems. For continuous development of Japan and improvement of the international competitiveness of Japan, development of a glass industry is essential. Both co- possession of technical issues by cooperation of the members, and breakdown of conventional structures of the industry are necessary. Clarification of technical issues, and cooperation of industry, academia and government is essential. The current state, promise and issues of domestic and overseas glass technology and its R and D are described. The joint target of an industrial strategy for researchers and engineers of every sector, and the approach to such target are showed from the viewpoint of the issues for Japan and preparation of common basic technology. The role of each sector for environment preparation and policy is described to achieve the target. (NEDO)

  19. [Basic research in traumatology and its contribution to routine operation].

    Science.gov (United States)

    Hausner, T; Redl, H

    2017-02-01

    Basic research in traumatology supports the clinical outcome of patients in trauma care and tries to find science-based solutions for clinical problems. Furthermore, institutions for basic research in traumatology usually offer training in different skills, such as how to write a scientific paper, or practice in microsurgery or intubation. Two examples of clinically significant research topics are presented.

  20. Environmental Economics Research Strategy (2005)

    Science.gov (United States)

    This 2005 Environmental Economics Research Strategy outlines EPA’s research effort to provide the necessary behavioral science foundation for making decisions and designing environmental policies at the least cost to American businesses and consumers.

  1. Math Fact Strategies Research Project

    Science.gov (United States)

    Boso, Annie

    2011-01-01

    An action research project was conducted in order to determine effective math fact strategies for first graders. The traditional way of teaching math facts included using timed tests and flashcards, with most students counting on their fingers or a number line. Six new research-based strategies were taught and analyzed to decide which methods…

  2. Pharmaceutical Research Strategies

    OpenAIRE

    Phlippen, Sandra; Vermeersch, Ad

    2008-01-01

    textabstractThis study analyses 1400 research projects of the top 20 R&D-spending pharmaceuticals to identify the determinants of successful research projects. We provide clear evidence that externally sourced projects and projects involving biotechnologies perform better than internal projects and chemical projects, respectively. Controlling for these effects, we find that big pharma should either build a critical mass of disease area knowledge or diversify projects over different DA’s in or...

  3. Basic petroleum research. Final report; Grunnleggende petroleumsforskning. Sluttrapport

    Energy Technology Data Exchange (ETDEWEB)

    Roesjoe, Bjarne; Stiksrud, Helge

    2004-07-01

    An overview of projects in the field of basic petroleum research (PetroForsk) is presented. A brief presentation of some of the projects is included, as well as political comments on the value of these projects. The research program Basic Petroleum Research (PetroForsk) was established in 1998 and ended in 2004. The program has been part of the Research Council of Norway's long-term effort in petroleum research (ml)

  4. Research strategies for clinicians.

    Science.gov (United States)

    Granger, B B

    2001-12-01

    If there is a story waiting to be told about nurses and research, it is this: research is part of our past, our present, and our future. Research gives "caring" a mental muscle that makes it stronger than caring would be without it. Since the Crimean War, research has been a foundational cornerstone of the profession. Florence Nightingale espoused caring and human touch but not without also observing and measuring important patient outcomes that identified the spread of infection via human contact. As a new generation of nurses emerges, we who have come before might serve them well to role model what we know: that strong research is strong nursing and that obtaining and using evidence in nursing practice results in better outcomes for those patients and families we serve. Is the story waiting to be told your story? Part of the story of nursing waiting to be told is your story. Regardless of why you embarked on your career in nursing and regardless of where your journey has taken you to this point, you are a part of the twenty-first century body of nursing, and your individual contribution is an important one. Listen to your patients with an ear toward measuring and evaluating outcomes. Reflect on the care you provided, the interventions you had to offer, and why. Should something have been different? Could something have been better? Find out ... measure it.

  5. Biomass production and basic research on photosynthesis

    International Nuclear Information System (INIS)

    Broda, E.

    1979-01-01

    This document is a report of the conference: research and development work in Austria, organized by Austrian ministry of science and research, the ASSA and the OMV-stock company in 1979, which took place in Vienna. The text is about the different possible forms of solar energy utilization. Broda analyses in detail the utilization and production of biomass. (nowak)

  6. Basic Research in Information Science in France.

    Science.gov (United States)

    Chambaud, S.; Le Coadic, Y. F.

    1987-01-01

    Discusses the goals of French academic research policy in the field of information science, emphasizing the interdisciplinary nature of the field. Areas of research highlighted include communication, telecommunications, co-word analysis in scientific and technical documents, media, and statistical methods for the study of social sciences. (LRW)

  7. Basic Research Methods for Librarians, Fifth Edition

    CERN Document Server

    Connaway, Lynn Silipigni

    2010-01-01

    Fifty-nine percent of the respondents to a 2000 survey reported that their master's programs had not adequately prepared them to conduct research, something that has not changed much in the ensuing decade. Yet, many library and information services (LIS) practitioners are routinely called upon to conducted job-related research. Where can they turn for the guidance they need?

  8. 32 CFR 272.3 - Definition of basic research.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Definition of basic research. 272.3 Section 272...) MISCELLANEOUS ADMINISTRATION AND SUPPORT OF BASIC RESEARCH BY THE DEPARTMENT OF DEFENSE § 272.3 Definition of... increasing fundamental knowledge and understanding in those fields of the physical, engineering...

  9. Marketing Strategy Research

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-03-31

    This report documents the research that has been undertaken as background for preparation of a marketing campaign for middle and high school students to increase interest in national security careers at the National Nuclear Security Administration. This work is a part of the National Security Preparedness Project (NSPP), being performed under a Department of Energy (DOE)/National Nuclear Security Administration (NNSA) grant. Previous research on the development of a properly trained and skilled national security workforce has identified a lack of interest by k-12 students in the STEM (Science, Technology, Engineering, and Mathematics) fields. Further, participation in these careers by women and minority populations is limited and is not increasing. Added to this are low educational achievement levels in New Mexico, where the marketing campaign will be deployed.

  10. Empathic design: Research strategies

    Directory of Open Access Journals (Sweden)

    Joyce Thomas

    2013-01-01

    Full Text Available This paper explores the role of empathy within new product development from the perspective of human-centred design. The authors have developed a range of empathic design tools and strategies that help to identify authentic human needs.For products and services to be effective, they need to satisfy both functional and emotional needs of individuals. In addition, the individual user needs to feel that the product and/or service has been designed ‘just for them’, otherwise they may misuse, underuse or abandon the product/service. This becomes critical with a product such as a Zimmer frame (walker, when it fails to resonate with the patient due to any stigma the patient may perceive, and thus remains unused.When training young designers to consider the wider community (people unlike themselves during the design process, it has proven extremely valuable to take them outside their comfort zones, by seeking to develop empathy with the end user for whom they are designing. Empathic modelling offers designers the opportunity to develop greater insight and understanding, in order to support more effective design outcomes. Sensitising designers to the different ways that individuals complete daily tasks has helped to diminish the gap between themselves and others (e.g. people with disabilities.The authors intend for this paper to resonate with health care providers. Human-centred design can help to refocus the designer, by placing the individual end user’s needs at the heart of their decision-making.

  11. Empathic design: Research strategies.

    Science.gov (United States)

    Thomas, Joyce; McDonagh, Deana

    2013-01-01

    This paper explores the role of empathy within new product development from the perspective of human-centred design. The authors have developed a range of empathic design tools and strategies that help to identify authentic human needs.For products and services to be effective, they need to satisfy both functional and emotional needs of individuals. In addition, the individual user needs to feel that the product and/or service has been designed 'just for them', otherwise they may misuse, underuse or abandon the product/service. This becomes critical with a product such as a Zimmer frame (walker), when it fails to resonate with the patient due to any stigma the patient may perceive, and thus remains unused.When training young designers to consider the wider community (people unlike themselves) during the design process, it has proven extremely valuable to take them outside their comfort zones, by seeking to develop empathy with the end user for whom they are designing. Empathic modelling offers designers the opportunity to develop greater insight and understanding, in order to support more effective design outcomes. Sensitising designers to the different ways that individuals complete daily tasks has helped to diminish the gap between themselves and others (e.g. people with disabilities).The authors intend for this paper to resonate with health care providers. Human-centred design can help to refocus the designer, by placing the individual end user's needs at the heart of their decision-making.

  12. Basic research in theoretical high energy physics. Progress report

    International Nuclear Information System (INIS)

    Adler, S.L.

    1984-01-01

    Activities in numerous areas of basic research in theoretical high energy physics are listed, and some highlights are given. Areas of research include statistical mechanics, quantum field theory, lattice gauge theories, and quantum gravity. 81 references

  13. Research Methodology in Global Strategy Research

    DEFF Research Database (Denmark)

    Cuervo-Cazurra, Alvaro; Mudambi, Ram; Pedersen, Torben

    2017-01-01

    We review advances in research methodology used in global strategy research and provide suggestions on how researchers can improve their analyses and arguments. Methodological advances in the extraction of information, such as computer-aided text analysis, and in the analysis of datasets......, such as differences-in-differences and propensity score matching, have helped deal with challenges (e.g., endogeneity and causality) that bedeviled earlier studies and resulted in conflicting findings. These methodological advances need to be considered as tools that complement theoretical arguments and well......-explained logics and mechanisms so that researchers can provide better and more relevant recommendations to managers designing the global strategies of their organizations....

  14. Basic Project Management Methodologies for Survey Researchers.

    Science.gov (United States)

    Beach, Robert H.

    To be effective, project management requires a heavy dependence on the document, list, and computational capability of a computerized environment. Now that microcomputers are readily available, only the rediscovery of classic project management methodology is required for improved resource allocation in small research projects. This paper provides…

  15. Basic research on cermet nuclear fuel

    Energy Technology Data Exchange (ETDEWEB)

    Ohashi, Hiroshi; Sto, Seichi [Hokkaido Univ., Sapporo (Japan). Faculty of Engineering; Takano, Masahide; Minato, Kazuo; Fukuda, Kosaku

    1998-01-01

    Production of cermet nuclear fuel having fine uranium dioxide (UO{sub 2}) particles dispersed in matrix metal requires basic property data on the compatibility of matrix metal with fission product compounds. It is thermodynamically suggested that, as burnup increases, cesium in oxide fuel reacts with the fuel, other fission products or cladding pipe and produces cesium uranates, cesium molybdate, or cesium chromate in stainless steel cladding pipe. Attempt was made to measure the thermal expansion coefficient and thermal conductivity of cesium uranates (Cs{sub 2}UO{sub 4} and Cs{sub 2}U{sub 2}O{sub 7}), cesium molybdate (Cs{sub 2}MoO{sub 4}) and cesium chromate (Cs{sub 2}CrO{sub 4}). Thermal expansion was measured by X-ray diffraction and determined by Cohen`s method. Thermal conductivity was obtained by measuring thermal diffusion by laser flash method. The thermal expansion of Cs{sub 2}UO{sub 4} and Cs{sub 2}U{sub 2}O{sub 7} is as low as 1.2% for the former and 1.0% for the latter, up to 1000K. The thermal expansion of Cs{sub 2}MoO{sub 4} is as high as that of Cs{sub 2}CrO{sub 4}, 2.1% for the former and 2.5% for the latter at temperatures from room temperature to 873K. Average thermal expansion in this temperature range is 4.4 x 10{sup -5} K{sup -1} for Cs{sub 2}MoO{sub 4} and 4.2 x 10{sup -5} K{sup -1}. The thermal expansion of Cs{sub 2}CrO{sub 4} is four times higher than that of UO{sub 2} and five times higher than that of Cr{sub 2}O{sub 3}. The thermal conductivity of Cs{sub 2}UO{sub 4} is nearly equal to that of Cs{sub 2}U{sub 2}O{sub 7} in absolute value and temperature dependency. Cs{sub 2}U{sub 2}O{sub 7}, having different thermal conductivity between {alpha} and {beta} phases, shows higher conductivity with {beta} than with {alpha}, about 1/4 of that of UO{sub 2} at 1000K. The thermal conductivity of Cs{sub 2}CrO{sub 4} is nearly equal to that of Cs{sub 2}MoO{sub 4} in absolute value and temperature dependency. (N.H.)

  16. [Platforms are needed for innovative basic research in ophthalmology].

    Science.gov (United States)

    Wang, Yi-qiang

    2012-07-01

    Basic research poses the cornerstone of technical innovation in all lines including medical sciences. Currently, there are shortages of professional scientists as well as technical supporting teams and facilities in the field of basic research of ophthalmology and visual science in China. Evaluation system and personnel policies are not supportive for innovative but high-risk-of-failure research projects. Discussion of reasons and possible solutions are given here to address these problems, aiming at promoting buildup of platforms hosting novel and important basic research in eye science in this country.

  17. UNIVERSITY BASIC RESEARCH AND APPLIED AGRICULTURAL BIOTECHNOLOGY

    OpenAIRE

    Xia, Yin

    2004-01-01

    I examine the effects of R&D inputs on the subset of life-science outputs which demonstrably has influenced later technology, as evidenced by literature citations in agricultural biotechnology patents. Universities are found to be a principal seedbed for cutting-edge technology development. A university's life-science research budget strongly affects its technology-relevant life-science output as well as graduate education.

  18. Management Strategies in Basic Education and Participation of Parents

    Directory of Open Access Journals (Sweden)

    Johel Furguerle-Rangel

    2016-05-01

    Full Text Available In the educational process it is necessary to use management paradigms and active participation of parents. The objective was to determine the use of management strategies by the director of basic education and participation of parents in the educational process. It is a descriptive, transversal and field study, whose instrument was a questionnaire of 26 closed-questions.   The sample comprised 16 directors, 52 teachers and 62 parents. For most managers and faculty the technique of brainstorming, involvement in decision-making, continues knowledge management and radical change are crucial in the educational process of children.   But mothers and fathers believe that managerial groups do not use strategies properly except for reengineering.   The mother and fathers are mainly involved in education management but not in the learning process. It is recommended the deepening of policy management training teaching force, through continuous training provided by the government and the promotion of family participation in the teaching-learning process of children.

  19. Translating basic research in cancer patient care

    Directory of Open Access Journals (Sweden)

    Marcello Maugeri-Saccà

    2011-01-01

    Full Text Available With the advent of molecular targeted therapies and the development of high-throughput biotechnologies, it has become evident that progress in cancer research is largely due to the creation of multidisciplinary teams able to plan clinical trials supported by appropriate molecular hypotheses. These efforts have culminated in the identification and validation of biomarkers predictive of response, as well as in the generation of more accurate prognostic tools. The identification of cancer stem cells has provided further insights into mechanisms of cancer, and many studies have tried to translate this biological notion into prognostic and predictive information. In this regard, new agents targeting key stemness-related pathways have entered the clinical development, and preliminary data suggested an encouraging antitumor activity.

  20. International Journal of Basic, Applied and Innovative Research

    African Journals Online (AJOL)

    International Journal of Basic, Applied and Innovative Research (IJBAIR) [ISSN: 2315-5388; E-ISSN: 2384 - 681X] is a peer reviewed Journal Publication of Anthonio Research Center and the International Society of Science Researchers (ISSCIR). IJBAIR accepts research articles, review articles, short reports, and ...

  1. [Basic research on BSE transmission to people].

    Science.gov (United States)

    Bodemer, W; Kaup, F J

    2002-08-01

    Prion diseases of animal and man belong to neurological diseases with amyloidal deposition of the respective proteins. As to prion disease, the cellular prionprotein is in its abnormal isoform(s) an essential component of prionprotein aggregates found in affected tissue. In contrast to all neurodegenerative diseases like Morbus Alzheimer or Huntington's disease, prion diseases are transmissible. Therefore, prion diseases were designated Transmissible Spongiform Encephalopathies (TSE). The diseases are well known since decades. Scrapie was first described around 1750, a BSE case was reported in the 1850, most likely a misdiagnosis, and in 1920/1930 the human Creutzfeldt-Jakob disease (CJD) had been described. Transmission of CJD i.e. Kuru had been suspected in the early 1950s and erronously classified as slow virus disease. The CJD transmission posed a problem to humans when transplants from CJD cases were used for treatment. Fortunately, these iatrogenic transmissions remained limited. But with the advent of BSE and appearance of variant CJD cases in the UK and some places in Europe scientists suspected that transmission from cattle to man could have happened. From animal models we know of successful transmission via several routes. Species barriers do not completely prevent transmission. Rather transmission barriers might exist controlling individual susceptibility against prions. Modes of transmission, susceptibility for transmission, identification of receptor molecules as well as molecular mechanisms of the transmission process are intensely investigated. Current knowledge let us to assume that inapparent stages of prion infection pretend a (not existing) species barrier. This inapparent infection preceeds overt disease and, thus, most re-search focuses on the development of highly sensitive assay systems for detection of minute amounts of pathological prionprotein in suspected cases. Inapparence also should warn us to underestimate BSE or human vCJD cases; at

  2. International Journal of Basic, Applied and Innovative Research

    African Journals Online (AJOL)

    2016-06-30

    Jun 30, 2016 ... International Journal of Basic, Applied and Innovative Research ... This study determined the extent of bacterial contamination of cow meat ... Sample Size/ Sample Collection: A total of 120 samples comprising of 40 samples ...

  3. International Journal of Basic, Applied and Innovative Research

    African Journals Online (AJOL)

    2014-09-30

    Sep 30, 2014 ... International Journal of Basic, Applied and Innovative Research. IJBAIR, 2014 ... as science and technology? ... On the contrary, many African communities are bedeviled by economic and leadership crisis, epidemics, poverty.

  4. Neutrons in basic and applied nuclear research - a review

    International Nuclear Information System (INIS)

    Bhattacharya, Sailajananda

    2013-01-01

    Energetic neutron sources, both white and mono-energetic, are widely used In basic nuclear physics as well as various multidisciplinary research. Precise measurement of various neutron induced reaction cross-sections are crucial for the design and development of new generation of reactors, like accelerator driven subcritical systems, nuclear incinerators, etc. A review of some recent trends in neutron induced basic and applied nuclear research will be presented in this talk. (author)

  5. Innovative and basic researches for high temperature technologies at HTTR

    International Nuclear Information System (INIS)

    Shiozawa, Shusaku

    1995-01-01

    The HTTR is the first HTGR which is under construction at JAERI. The objectives of the HTTR are to establish basic technologies for HTGRs, to upgrade technologies for HTGRs and to conduct innovative and basic researches for high temperature technologies. The first two are concerned with HTGR developments. The last one is not necessarily for HTGR developments, but for future innovative researches which are expected to be applied to various technologies. (author)

  6. Basic research needs for management and disposal of DOE wastes

    International Nuclear Information System (INIS)

    Grazis, B.M.; Schulz, W.W.

    1991-04-01

    This document was chartered by the Department of Energy (DOE), Office of Energy Research. It identifies and describes 87 basic research needs in support of advanced technology for management and disposal of Department of Energy radioactive, hazardous chemical, and mixed wastes. A team of scientists and engineers from several DOE laboratories and sites, from academia, and from industry identified and described the basic research needs called out in this report. Special efforts were made to ensure that basic research needs related to management and disposal of any hazardous chemical wastes generated at nonnuclear DOE sites and facilities were properly identified. It is hoped that scientists in both DOE and nongovernment laboratories and institutions will find this document useful when formulating research efforts relevant to waste management and disposal. For management and disposal of DOE radioactive and mixed wastes, basic research needs are identified in nine separate action areas. Basic research needs for management and disposal of DOE hazardous chemical wastes are identified in five action areas. Sufficient description and background information are provided in the report for each particular research need to enable qualified and imaginative scientists to conceive research efforts and programs that will meet the need. 28 refs., 7 tabs

  7. Research strategies for human performance

    International Nuclear Information System (INIS)

    Carlsson, Lennart

    1998-01-01

    This document reflects basic proposals derived from the discussions and results by the expert group on human performance within the frame of an OECD study on nuclear safety research. Different topics have identified which are herein briefly presented: cognitive models and errors of commission, organizational practices, validation of existing techniques for human reliability analysis, control room design and man-machine interactions, use of simulators, improvement of methods for evaluation of operating experience, safety culture, operator aids, shutdown, decommissioning

  8. Thymic epithelial tumours: from basic principles to individualised treatment strategies

    Directory of Open Access Journals (Sweden)

    Nicolas Girard

    2013-03-01

    Full Text Available Thymic epithelial tumours represent a wide range of anatomical, clinical, histological and molecular malignant entities that may be aggressive and difficult to treat. The histopathological classification distinguishes thymomas from thymic carcinomas. Thymomas may be associated with autoimmune disorders. The management of thymic epithelial tumours is a paradigm of co-operation between clinicians, surgeons and pathologists, from establishing the diagnosis to organising the multimodal therapeutic strategy. Surgery is the mainstay of the curative-intent treatment, as complete resection represents the most significantly favourable prognostic factor on overall survival. In case of invasion of intra-thoracic structures and/or dissemination to the pleura and the pericardium, precluding complete resection to be achieved, primary chemotherapy has been used to reduce the tumour burden, possibly allowing subsequent surgery and/or radiotherapy. Novel strategies are needed, especially for refractory, recurrent tumours and thymic carcinomas, which carry a poor prognosis. Personalised approaches are currently being developed, as potentially “druggable” molecular targets are emerging from recent integrated genomic analyses. Along with the large variety of questions relative to the treatment strategy, thymic epithelial tumours represent a model of therapeutic implementation and achievement in orphan thoracic oncology, showing how the advent of new results induces new questions, as well as diversifies further clinical research directions and international collaborative initiatives.

  9. Decision Strategy Research: Policy Support

    International Nuclear Information System (INIS)

    Hardeman, F.

    2000-01-01

    The objective of SCK-CEN's R and D programme on decision strategy research are (1) to support and advise the Belgian authorities on specific problems concerning existing and potential hazards from exposure to ionising radiation, both in normal and emergency situations; (2) to perform research on relevant topics that might have an important impact on decision making related to nuclear applications, including social and economic sciences. Main achievements in this area in 1999 are described

  10. Basic Research Needs for Carbon Capture: Beyond 2020

    Energy Technology Data Exchange (ETDEWEB)

    Alivisatos, Paul [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Buchanan, Michelle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2010-03-04

    that contains many other gaseous components. The related processes of precombustion capture and oxycombustion pose similar challenges. It is this nexus of high-speed capture with high selectivity and minimal energy loss that makes this a true grand challenge problem, far beyond any of today’s artificial molecular manipulation technologies, and one whose solution will drive the advancement of molecular science to a new level of sophistication. We have only to look to nature, where such chemical separations are performed routinely, to imagine what may be achieved. The hemoglobin molecule transports oxygen in the blood rapidly and selectively and releases it with minimal energy penalty. Despite our improved understanding of how this biological system works, we have yet to engineer a molecular capture system that uses the fundamental cooperativity process that lies at the heart of the functionality of hemoglobin. While such biological examples provide inspiration, we also note that newly developed theoretical and computational capabilities; the synthesis of new molecules, materials, and membranes; and the remarkable advances in characterization techniques enabled by the Department of Energy’s measurement facilities all create a favorable environment for a major new basic research push to solve the carbon capture problem within the next decade. The Department of Energy has established a comprehensive strategy to meet the nation’s needs in the carbon capture arena. This framework has been developed following a series of workshops that have engaged all the critical stakeholder communities. The strategy that has emerged is based upon a tiered approach, with Fossil Energy taking the lead in a series of applied research programs that will test and extend our current systems. ARPA-E (Advanced Research Projects Agency–Energy) is supporting potential breakthroughs based upon innovative proposals to rapidly harness today’s technical capabilities in ways not previously

  11. Controlling Subsurface Fractures and Fluid Flow: A Basic Research Agenda

    Energy Technology Data Exchange (ETDEWEB)

    Pyrak-Nolte, Laura J [Purdue Univ., West Lafayette, IN (United States); DePaolo, Donald J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Univ. of California, Berkeley, CA (United States); Pietraß, Tanja [USDOE Office of Science, Washington, DC (United States)

    2015-05-22

    From beneath the surface of the earth, we currently obtain about 80-percent of the energy our nation consumes each year. In the future we have the potential to generate billions of watts of electrical power from clean, green, geothermal energy sources. Our planet’s subsurface can also serve as a reservoir for storing energy produced from intermittent sources such as wind and solar, and it could provide safe, long-term storage of excess carbon dioxide, energy waste products and other hazardous materials. However, it is impossible to underestimate the complexities of the subsurface world. These complexities challenge our ability to acquire the scientific knowledge needed for the efficient and safe exploitation of its resources. To more effectively harness subsurface resources while mitigating the impacts of developing and using these resources, the U.S. Department of Energy established SubTER – the Subsurface Technology and Engineering RD&D Crosscut team. This DOE multi-office team engaged scientists and engineers from the national laboratories to assess and make recommendations for improving energy-related subsurface engineering. The SubTER team produced a plan with the overall objective of “adaptive control of subsurface fractures and fluid flow.”This plan revolved around four core technological pillars—Intelligent Wellbore Systems that sustain the integrity of the wellbore environment; Subsurface Stress and Induced Seismicity programs that guide and optimize sustainable energy strategies while reducing the risks associated with subsurface injections; Permeability Manipulation studies that improve methods of enhancing, impeding and eliminating fluid flow; and New Subsurface Signals that transform our ability to see into and characterize subsurface systems. The SubTER team developed an extensive R&D plan for advancing technologies within these four core pillars and also identified several areas where new technologies would require additional basic research

  12. Polymerase chain reaction: basic protocol plus troubleshooting and optimization strategies.

    Science.gov (United States)

    Lorenz, Todd C

    2012-05-22

    In the biological sciences there have been technological advances that catapult the discipline into golden ages of discovery. For example, the field of microbiology was transformed with the advent of Anton van Leeuwenhoek's microscope, which allowed scientists to visualize prokaryotes for the first time. The development of the polymerase chain reaction (PCR) is one of those innovations that changed the course of molecular science with its impact spanning countless subdisciplines in biology. The theoretical process was outlined by Keppe and coworkers in 1971; however, it was another 14 years until the complete PCR procedure was described and experimentally applied by Kary Mullis while at Cetus Corporation in 1985. Automation and refinement of this technique progressed with the introduction of a thermal stable DNA polymerase from the bacterium Thermus aquaticus, consequently the name Taq DNA polymerase. PCR is a powerful amplification technique that can generate an ample supply of a specific segment of DNA (i.e., an amplicon) from only a small amount of starting material (i.e., DNA template or target sequence). While straightforward and generally trouble-free, there are pitfalls that complicate the reaction producing spurious results. When PCR fails it can lead to many non-specific DNA products of varying sizes that appear as a ladder or smear of bands on agarose gels. Sometimes no products form at all. Another potential problem occurs when mutations are unintentionally introduced in the amplicons, resulting in a heterogeneous population of PCR products. PCR failures can become frustrating unless patience and careful troubleshooting are employed to sort out and solve the problem(s). This protocol outlines the basic principles of PCR, provides a methodology that will result in amplification of most target sequences, and presents strategies for optimizing a reaction. By following this PCR guide, students should be able to: • Set up reactions and thermal cycling

  13. THE BASIC PRINCIPLES OF RESEARCH IN NEUROEDUCATION STUDIES

    OpenAIRE

    Ali Nouri

    2016-01-01

    The present paper assembles contributions from the areas of education, psychology, cognitive science, and of course, neuroeducation itself to introduce the basic principles of research in the field of neuroeducation studies. It is particularly important, as such it is a useful way to justify researchers about what neuroeducation as a specific domain do that no other field can do as well or cannot do at all. Based on the literature reviewed, neuroeducational research can be understood as an inte...

  14. Accelerating complex for basic researches in the nuclear physics

    NARCIS (Netherlands)

    Dovbnya, A.N.; Guk, I.S.; Kononenko, S.G.; Peev, F.A.; Tarasenko, A.S.; Botman, J.I.M.

    2009-01-01

    In 2003 in NSC KIPT was begun the work on development the project of accelerator, base facility IHEPNP NSC KIPT electron recirculator SALO. The accelerator will be disposed in target hall of accelerator LU 2000 complex. It is projected first of all as facility for basic researches in the field of

  15. Basic and applied research at NTT and postgraduate education

    International Nuclear Information System (INIS)

    Kimura, Tatsuya

    1995-01-01

    Several current research topics, which are studied at NTT Basic Research Laboratories, are reviewed in the fields of semiconductor physics, quantum optics and biophysics. These topics include the surface structure transition of GaAs, InAs and Si, electron transport in low-dimensional structure, microcavity quantum-wire semiconductor lasers, quantum nondemolition measurement of fibre solitons, and artificial network development of cultivated neural cells. 32 refs., 33 fig

  16. Contributing to research: the basic elements of a scientific manuscript

    International Nuclear Information System (INIS)

    Kurmis, A.P.

    2003-01-01

    The changing focus within medical and allied health disciplines towards evidence-based practice has resulted in an increasing acceptance of research and professional researchers. Despite the shift towards tertiary degree-based training for medical imaging and allied specialty streams, with many teaching institutions now incorporating compulsory research components into their final year curriculum, the level of active involvement in research among graduates remains low. In addition to this, many of those who completed their training before the introduction of university degree courses have had little or no exposure to hands-on research. While not overtly difficult, the process of 'writing up' the findings of a research endeavour for presentation to peers can often seem a somewhat daunting task, especially for novice researchers. The structure of a scientific manuscript however follows a relatively basic and universally accepted pattern, adherence to which can greatly simplify the writing process. To contribute to a wider understanding of research, the purpose of this paper is to provide an overview of the basic elements of a scientific research paper for journal publication. The outline provided, while not intended to be a recipe for manuscript construction, will provide a fundamental framework to assist student, junior or inexperienced researchers in their writings

  17. International strategy for Nanotechnology Research

    International Nuclear Information System (INIS)

    Roco, M.C.

    2001-01-01

    The worldwide nanotechnology research and development (R and D) investment reported by government organizations has increased by a factor of 3.5 between 1997 and 2001, and the highest rate of 90% is in 2001. At least 30 countries have initiated or are beginning national activities in this field. Scientists have opened a broad net of discoveries that does not leave any major research area untouched in physical, biological, and engineering sciences. Industry has gained confidence that nanotechnology will bring competitive advantages. The worldwide annual industrial production is estimated to exceed $1 trillion in 10-15 years from now, which would require about 2 million nanotechnology workers. U.S. has initiated a multidisciplinary strategy for development of science and engineering fundamentals through the National Nanotechnology Initiative. Japan and Europe have broad programs, and their current plans look ahead to four to five years. Other countries have encouraged their own areas of strength, several of them focusing on fields of the potential markets. Differences among countries are observed in the research domain they are aiming for, the level of program integration into various industrial sectors, and in the time scale of their R and D targets. Nanotechnology is growing in an environment where international interactions accelerate in science, education and industrial R and D. A global strategy of mutual interest is envisioned by connecting individual programs of contributing countries, professional communities, and international organizations

  18. Future plant of basic research for nuclear energy by university researchers

    International Nuclear Information System (INIS)

    Shibata, Toshikazu

    1984-01-01

    National Committee for Nuclear Energy Research, Japan Science Council has completed a future plan for basic nuclear energy research by university researchers. The JSC has recommended the promotion of basic research for nuclear energy based on the plan in 1983. The future plan consists of four main research fields, namely, (1) improvements of reactor safety, (2) down stream, (3) thorium fuel reactors, and (4) applications of research reactor and radioisotopes. (author)

  19. Basic Solar Energy Research in Japan (2011 EFRC Forum)

    International Nuclear Information System (INIS)

    Domen, Kazunari

    2011-01-01

    Kazunari Domen, Chemical System Engineering Professor at the University of Tokyo, was the second speaker in the May 26, 2011 EFRC Forum session, 'Global Perspectives on Frontiers in Energy Research.' In his presentation, Professor Domen talked about basic solar energy research in Japan. The 2011 EFRC Summit and Forum brought together the EFRC community and science and policy leaders from universities, national laboratories, industry and government to discuss 'Science for our Nation's Energy Future.' In August 2009, the Office of Science established 46 Energy Frontier Research Centers. The EFRCs are collaborative research efforts intended to accelerate high-risk, high-reward fundamental research, the scientific basis for transformative energy technologies of the future. These Centers involve universities, national laboratories, nonprofit organizations, and for-profit firms, singly or in partnerships, selected by scientific peer review. They are funded at $2 to $5 million per year for a total planned DOE commitment of $777 million over the initial five-year award period, pending Congressional appropriations. These integrated, multi-investigator Centers are conducting fundamental research focusing on one or more of several 'grand challenges' and use-inspired 'basic research needs' recently identified in major strategic planning efforts by the scientific community. The purpose of the EFRCs is to integrate the talents and expertise of leading scientists in a setting designed to accelerate research that transforms the future of energy and the environment.

  20. [Basic research during residency in Israel: is change needed?].

    Science.gov (United States)

    Fishbain, Dana; Shoenfeld, Yehuda; Ashkenazi, Shai

    2013-10-01

    A six-month research period is a mandatory part of the residency training program in most basic specialties in Israel and is named: the "basic science period". This is the only period in an Israeli physician's medical career which is dedicated strictly to research, accentuating the importance of medical research to the quality of training and level of medicine in Israel. From another point of view, one may argue that in an era of shortage of physicians on the one hand and the dizzying rate of growth in medical knowledge on the other hand, every moment spent training in residency is precious, therefore, making the decision of whether to dedicate six months for research becomes ever more relevant. This question is currently raised for discussion once again by the Scientific Council of the Israeli Medical Association. The Scientific Council lately issued a call for comments sent to all Israeli physicians, asking their opinion on several key questions regarding basic science research. Learning the public's opinion will serve as a background for discussion. A total of 380 physicians responded to the call and specified their standpoint on the subject, among them heads of departments, units and clinics, senior physicians and residents. The findings pointed to strong support in maintaining the research period as part of residency training due to its importance to medical training and medicine, although half the respondents supported the use of various alternative formats for research together with the existing format. Those alternative format suggestions will be thoroughly reviewed. A smaller group of respondents supported allowing residents a choice between two tracks--with or without a research period, and only a few were in favor of canceling the research requirement altogether. The writers maintain that the "basic science period" of research during residency training is vital and its contribution to the high level of specialists and high level of medicine requires its

  1. Geoengineering: Basic science and ongoing research efforts in China

    Directory of Open Access Journals (Sweden)

    Long Cao

    2015-09-01

    Full Text Available Geoengineering (also called climate engineering, which refers to large-scale intervention in the Earth's climate system to counteract greenhouse gas-induced warming, has been one of the most rapidly growing areas of climate research as a potential option for tackling global warming. Here, we provide an overview of the scientific background and research progress of proposed geoengineering schemes. Geoengineering can be broadly divided into two categories: solar geoengineering (also called solar radiation management, or SRM, which aims to reflect more sunlight to space, and carbon dioxide removal (CDR, which aims to reduce the CO2 content in the atmosphere. First, we review different proposed geoengineering methods involved in the solar radiation management and carbon dioxide removal schemes. Then, we discuss the fundamental science underlying the climate response to the carbon dioxide removal and solar radiation management schemes. We focus on two basic issues: 1 climate response to the reduction in solar irradiance and 2 climate response to the reduction in atmospheric CO2. Next, we introduce an ongoing geoengineering research project in China that is supported by National Key Basic Research Program. This research project, being the first coordinated geoengineering research program in China, will systematically investigate the physical mechanisms, climate impacts, and risk and governance of a few targeted geoengineering schemes. It is expected that this research program will help us gain a deep understanding of the physical science underlying geoengineering schemes and the impacts of geoengineering on global climate, in particular, on the Asia monsoon region.

  2. Assuring both quality and creativity in basic research

    Energy Technology Data Exchange (ETDEWEB)

    Bodnarczuk, M.

    1990-04-12

    How does one assure that both quality and creativity are obtained in basic research environments QA theoreticians have attempted to develop workable definitions of quality, but in more reflective moments, these definitions often fail to capture the deeper essence of the idea of quality.'' This paper asserts that creativity (as a product of the human mind) is a concrete interface between perfunctory definitions of quality (conformance to specifications) and more philosophical speculations about the nature of quality- related ultimates'' like elegance or beauty. In addition, we describe the distinction between creative ideas and creative acts and highlight one of the major inhibitors of creativity, fear. Finally we show that highly creative people often have an irreverent attitude toward boundaries and established authority, and discuss how one can allow for this when designing a QA program in a basic research environment.

  3. The progress of basic research for ADS in China

    International Nuclear Information System (INIS)

    Xia Haihong; Zhao Zhixiang; Ding Dazhao

    2002-01-01

    The conceptual study of Accelerator Driven System (ADS), which is an entirely new approach for the exploitation of next generation nuclear energy, had lasted for about five years and ended in 1999 in China. From then a five years program of basic research for ADS has been launched. According to present technical and budget status in China, a moderate style multi-purpose verification system is under consideration, which consists of a low energy accelerator (150MeV/3mA proton linac) and a swimming pool light water sub-critical reactor. CIAE (China Institute of Atomic Energy), IHEP (Institute of High Energy Physics), PKU-IHIP (Institute of Heavy Ion Physics in Peking University) and other institutions are jointly carrying on the basic research of ADS. The main results on ADS system optimization, ADS related reactor physics study, nuclear physics study, accelerator physics and technology study, material compatibility study, material radiation effects study has been reported. (author)

  4. Basic Design of the Cold Neutron Research Facility in HANARO

    International Nuclear Information System (INIS)

    Kim, Hark Rho; Lee, K. H.; Kim, Y. K.

    2005-09-01

    The HANARO Cold Neutron Research Facility (CNRF) Project has been embarked in July 2003. The CNRF project has selected as one of the radiation technology development project by National Science and Technology Committee in June 2002. In this report, the output of the second project year is summarized as a basic design of cold neutron source and related systems, neutron guide, and neutron scattering instruments

  5. Basic Design of the Cold Neutron Research Facility in HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hark Rho; Lee, K. H.; Kim, Y. K. (and others)

    2005-09-15

    The HANARO Cold Neutron Research Facility (CNRF) Project has been embarked in July 2003. The CNRF project has selected as one of the radiation technology development project by National Science and Technology Committee in June 2002. In this report, the output of the second project year is summarized as a basic design of cold neutron source and related systems, neutron guide, and neutron scattering instruments.

  6. US nuclear reaction data program in support of basic research

    International Nuclear Information System (INIS)

    Bhat, M.R.; Chadwick, M.B.; Smith, M.S.

    1997-01-01

    Information about the US Nuclear Reaction Data Network (USNRDN) such as its members, work in progress, summaries of meetings, and organizational details may be found in its WWW Homepage. This paper is an overview of the data support provided by the network for basic research in nuclear astrophysics, radioactive ion beams, high energy heavy-ion and electron interactions and related activities involving all aspects of data stewardship

  7. Progress report 1986-1987 Basic Research Department

    International Nuclear Information System (INIS)

    1988-01-01

    A report is presented of the activities performed by the Basic Research Department of the Bariloche Atomic Center during the period 1986-1987. In this report, works on different subjects related to physics are grouped: atomic collisions, low temperatures, magnetic resonance, metals, neutrons and reactors and theoretical physics (computational, elementary particles, nuclear physics and solid states). In addition, Appendix I and II regarding the staff and visiting scientists, respectively, and publications and conferences are included [es

  8. Report 1984-1985. Department of Basic Research

    International Nuclear Information System (INIS)

    1986-01-01

    A report is presented of the activities performed by the Department of Basic research of the Bariloche Atomic Center during the period 1984-1985. In this report, works on different subjects related to Physics, are grouped in six sections: Low temperatures, Atomic collisions, Metals, Neutrons and Reactors, Magnetic Resonances and Theory. In addition, a list of publications, made by the Department during said period, is included. (M.E.L.) [es

  9. Geographical and temporal distribution of basic research experiments in homeopathy.

    Science.gov (United States)

    Clausen, Jürgen; van Wijk, Roeland; Albrecht, Henning

    2014-07-01

    The database HomBRex (Homeopathy Basic Research experiments) was established in 2002 to provide an overview of the basic research already done on homeopathy (http://www.carstens-stiftung.de/hombrex). By this means, it facilitates the exploration of the Similia Principle and the working mechanism of homeopathy. Since 2002, the total number of experiments listed has almost doubled. The current review reports the history of basic research in homeopathy as evidenced by publication dates and origin of publications. In July 2013, the database held 1868 entries. Most publications were reported from France (n = 267), followed by Germany (n = 246) and India (n = 237). In the last ten years, the number of publications from Brazil dramatically increased from n = 13 (before 2004) to n = 164 (compared to n = 251 published in France before 2004, and n = 16 between 2004 and 2013). The oldest database entry was from Germany (1832). Copyright © 2014 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.

  10. Research strategies for human performance

    International Nuclear Information System (INIS)

    1998-01-01

    Knowledge about factors that influence Human Performance is essential for the safety of nuclear power plant operation. Through a number of tasks, workshops and projects, experience is shared among OECD countries. At its December 1996 meeting, the CSNI endorsed the SESAR/CAF report on 'Nuclear Safety Research in OECD Countries: Capabilities and Facilities' and requested that the Principal Working Groups (PWGs) review existing co-operative programmes and develop specifications for programmes which address the identified needs. Following discussions between the chairmen of these PWGs and the NEA Secretariat, it was concluded that, for this technical area, the development of programme specifications must be preceded by the development of a strategic document that further elaborates the conclusions of the SESAR/CAF report and set out the general orientation of the research over the medium and long term. Accordingly, a group of senior experts met in August 1997 to discuss possible strategies in the area of Human Performance. The objectives of this meeting were: - To exchange information on existing plans and strategies by different Member countries; - To determine relevant issues and realistic medium/long-term targets and expectations for their resolution, and - To determine, in general sense, possible research programmes, their priority and their likelihood for success. This document is the result of this meeting. Its objective is to present to the CSNI proposals for future work on Human Performance research. The proposals are built upon the work performed to date by PWG1 and PWG5. Carrying out these proposals will continue to require close coordination on joint activities between these two PWGs. Reinforced systematic networking activities are needed particularly in management and organisational performance research to initiate and manage comparison and benchmarking activities. Synchronising the availability of funding is a specific problem in many cases. Since most

  11. Basic research and industrialization of CANDU advanced fuel

    Energy Technology Data Exchange (ETDEWEB)

    Chun, Suk Ho; Park, Joo Hwan; Jun, Ji Su [and others

    2000-04-01

    Wolsong Unit 1 as the first heavy water reactor in Korea has been in service for 17 years since 1983. It would be about the time to prepare a plan for the solution of problems due to aging of the reactor. The aging of CANDU reactor could lead especially to the steam generator cruding and pressure tube sagging and creep and then decreases the operation margin to make some problems on reactor operations and safety. The counterplan could be made in two ways. One is to repair or modify reactor itself. The other is to develop new advanced fuel to increase of CANDU operation margin effectively, so as to compensate the reduced operation margin. Therefore, the first objectives in the present R and D is to develop the CANFLEX-NU (CANDU Flexible fuelling-Natural Uranium) fuel as a CANDU advanced fuel. The second objectives is to develop CANDU advanced fuel bundle to utilize advanced fuel cycles such as recovered uranium, slightly enriched uranium, etc. and so to raise adaptability for change in situation of uranium market. Also, it is to develop CANDU advanced fuel technology which improve uranium utilization to cope with a world-wide imbalance between uranium supply and demand, without significant modification of nuclear reactor design and refuelling strategies. As the implementations to achieve the above R and D goal, the work contents and scope of technology development of CANDU advanced fuel using natural uranium (CANFLEX-NU) are the fuel element/bundle designs, the nuclear design and fuel management analysis, the thermalhydraulic analysis, the safety analysis, fuel fabrication technologies, the out-pile thermalhydraulic test and in-pile irradiation tests performed. At the next, the work scopes and contents of feasibility study of CANDU advanced fuel using recycled uranium (CANFLEX-RU) are the fuel element/bundle designs, the reactor physics analysis, the thermalhydraulic analysis, the basic safety analysis of a CANDU-6 reactor with CANFLEX-RU fuel, the fabrication and

  12. Basic research and industrialization of CANDU advanced fuel

    International Nuclear Information System (INIS)

    Chun, Suk Ho; Park, Joo Hwan; Jun, Ji Su

    2000-04-01

    Wolsong Unit 1 as the first heavy water reactor in Korea has been in service for 17 years since 1983. It would be about the time to prepare a plan for the solution of problems due to aging of the reactor. The aging of CANDU reactor could lead especially to the steam generator cruding and pressure tube sagging and creep and then decreases the operation margin to make some problems on reactor operations and safety. The counterplan could be made in two ways. One is to repair or modify reactor itself. The other is to develop new advanced fuel to increase of CANDU operation margin effectively, so as to compensate the reduced operation margin. Therefore, the first objectives in the present R and D is to develop the CANFLEX-NU (CANDU Flexible fuelling-Natural Uranium) fuel as a CANDU advanced fuel. The second objectives is to develop CANDU advanced fuel bundle to utilize advanced fuel cycles such as recovered uranium, slightly enriched uranium, etc. and so to raise adaptability for change in situation of uranium market. Also, it is to develop CANDU advanced fuel technology which improve uranium utilization to cope with a world-wide imbalance between uranium supply and demand, without significant modification of nuclear reactor design and refuelling strategies. As the implementations to achieve the above R and D goal, the work contents and scope of technology development of CANDU advanced fuel using natural uranium (CANFLEX-NU) are the fuel element/bundle designs, the nuclear design and fuel management analysis, the thermalhydraulic analysis, the safety analysis, fuel fabrication technologies, the out-pile thermalhydraulic test and in-pile irradiation tests performed. At the next, the work scopes and contents of feasibility study of CANDU advanced fuel using recycled uranium (CANFLEX-RU) are the fuel element/bundle designs, the reactor physics analysis, the thermalhydraulic analysis, the basic safety analysis of a CANDU-6 reactor with CANFLEX-RU fuel, the fabrication and

  13. ENSI research strategy; Forschungsstrategie des Eidgenoessischen Nuklearsicherheitsinspektorats ENSI

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-06-15

    This brief report issued by the Swiss Federal Nuclear Safety Inspectorate (ENSI) reviews the inspectorate's activities and the strategy being followed. The basic principles involved in the institute's research and its financing are discussed, as are six basic aims being followed. The criteria used for the support of various research projects are examined and the methods used to control and monitor work on regulatory safety research are described. Interaction with the Swiss National Cooperative for the Disposal of Radioactive Waste NAGRA is discussed and four-year programs concerning research subjects are noted.

  14. Strategies for getting the 'bio-basics' right.

    Science.gov (United States)

    Carr, Derry

    2014-06-01

    Energy and utilities management specialist, Dalkia, boasts over 75 years' experience within the healthcare sector. It has helped more than 100 hospitals throughout the UK to meet carbon reduction strategies and reduce costs. Here Derry Carr, the company's technical manager and group gas manager, explores the viability of on-site biomass energy, and discusses the key considerations for healthcare sites seeking to make the switch.

  15. A basic strategy for financing long term care.

    Science.gov (United States)

    Greenberg, J A; Leutz, W N

    1984-02-01

    As pressure mounts to contain Medicaid long term care spending, short-range "quick fixes" must be avoided. Three such false solutions in particular have shortcomings that may actually exacerbate long term care's financial dilemma because they are based on inadequate definitions of the problem. Two of these proposals--legislation to broaden family responsibility toward institutionalized elders on Medicaid and expanded state power to put liens on such elders' real property--err by trying to mandate "caring" and are predicated on a misunderstanding of the "spend-down" problem. The other proposal--to provide tax incentives to family members who care for elders--requires a large administrative apparatus, assumes an elasticity of supply that may not exist, and could disrupt the "gift relationship" on which family exchanges are often based. What is needed is a strategy with short term, intermediate, and long term objectives that move toward an insurance approach. The short term plan should lay the groundwork for intermediate strategy and control costs by changing rate-setting methods and putting limits on facility construction. The intermediate plan should change the problem's definition from one of merely controlling Medicaid long term care expenditures to one of efficiently managing state resources for the elderly through the development of state financing and local delivery systems that target older persons in greatest need. An effective means of doing this is through the creation of social/HMOs, which have five key features: integration of service responsibility and authority; flexibility in organizational design; balanced clientele; pooled prepaid funding; and financial risk for the provider organization. Finally, the long term strategy should transfer much of the long term care financial burden from individuals and state Medicaid agencies to insurance mechanisms. Many individuals would thus avoid impoverishment caused by health care spending and Medicaid would

  16. [Basic theory and research method of urban forest ecology].

    Science.gov (United States)

    He, Xingyuan; Jin, Yingshan; Zhu, Wenquan; Xu, Wenduo; Chen, Wei

    2002-12-01

    With the development of world economy and the increment of urban population, the urban environment problem hinders the urban sustainable development. Now, more and more people realized the importance of urban forests in improving the quality of urban ecology. Therefore, a new subject, urban forest ecology, and correlative new concept frame in the field formed. The theoretic foundation of urban forest ecology derived from the mutual combination of theory relating to forest ecology, landscape ecology, landscape architecture ecology and anthrop-ecology. People survey the development of city from the view of ecosystem, and regard the environment, a colony of human, animals and plants, as main factors of the system. The paper introduces systematically the urban forest ecology as follows: 1) the basic concept of urban forest ecology; 2) the meaning of urban forest ecology; 3) the basic principle and theoretic base of urban forest ecology; 4) the research method of urban forest ecology; 5) the developmental expectation of urban forest ecology.

  17. THE BASIC PRINCIPLES OF RESEARCH IN NEUROEDUCATION STUDIES

    Directory of Open Access Journals (Sweden)

    Ali Nouri

    2016-06-01

    Full Text Available The present paper assembles contributions from the areas of education, psychology, cognitive science, and of course, neuroeducation itself to introduce the basic principles of research in the field of neuroeducation studies. It is particularly important, as such it is a useful way to justify researchers about what neuroeducation as a specific domain do that no other field can do as well or cannot do at all. Based on the literature reviewed, neuroeducational research can be understood as an interdisciplinary endeavor to develop an insightful understanding and holistic picture of problems related to learning and education. It thus epistemologically is based on an integrated methodological pluralism paradigm. This requires researchers to understand multiple methods and methodologies and employ as they formulate their own research projects. Researchers have a critical role to play in providing systematic evidence and conclusions that are scientifically valid and reliable and educationally relevant and usable. One significant implication of this argument is the need to strengthen the quality of the research component in graduate programs of the field and train interested researchers in the identification and formulation of relevant research questions.

  18. Does Fostering Reasoning Strategies for Relatively Difficult Basic Combinations Promote Transfer by K-3 Students?

    Science.gov (United States)

    Baroody, Arthur J.; Purpura, David J.; Eiland, Michael D.; Reid, Erin E.; Paliwal, Veena

    2016-01-01

    How best to promote fluency with basic sums and differences is still not entirely clear. Some advocate a direct approach--using drill to foster memorization of basic facts by rote. Others recommend an indirect approach that first involves learning reasoning strategies. The purpose of the present study was to evaluate the efficacy of 2…

  19. Basic research in evolution and ecology enhances forensics.

    Science.gov (United States)

    Tomberlin, Jeffery K; Benbow, M Eric; Tarone, Aaron M; Mohr, Rachel M

    2011-02-01

    In 2009, the National Research Council recommended that the forensic sciences strengthen their grounding in basic empirical research to mitigate against criticism and improve accuracy and reliability. For DNA-based identification, this goal was achieved under the guidance of the population genetics community. This effort resulted in DNA analysis becoming the 'gold standard' of the forensic sciences. Elsewhere, we proposed a framework for streamlining research in decomposition ecology, which promotes quantitative approaches to collecting and applying data to forensic investigations involving decomposing human remains. To extend the ecological aspects of this approach, this review focuses on forensic entomology, although the framework can be extended to other areas of decomposition. Published by Elsevier Ltd.

  20. The basics of spherical tokamaks and progress in European research

    International Nuclear Information System (INIS)

    Gusev, V K; Alladio, F; Morris, A W

    2003-01-01

    When the aspect ratio of a tokamak (A = R/a) decreases significantly, there is a transformation of the well studied tokamak toroidal magnetic configuration into the spherical tokamak (ST) configuration. This configuration has high natural plasma elongation and triangularity and other unique equilibrium and stability properties of ST configuration, which are discussed in this paper. European research into ST physics is well advanced in spite of the young age of this branch of fusion science. An overview of selected experimental and theoretical results obtained at Ioffe, Culham and Frascati is given with the emphasis on their complementarity and links to the main stream of tokamak research, such as ITER. An outline of the basic ST advantages and the potential of ST research for new insights into magnetic confinement is also given. More detailed descriptions of recent advances in ST theory and experiment may be found in the invited papers by Akers and Ono in the proceedings of this conference

  1. Basic and clinical research advances in ischemic stroke

    Directory of Open Access Journals (Sweden)

    Yuan-yuan MA

    2018-01-01

    Full Text Available Stroke is the most common cerebrovascular disease worldwide, which seriously affects life quality of survivals and results in huge economic burden of families and society. In terms of clinical treatment for ischemic stroke, apart from thrombolytic therapy with recombinant tissue-type plasminogen activator (rt-PA, the occurrence and successful application of endovascular thrombectomy in patients of ischemic stroke is a major breakthrough. Meanwhile, many novel clinical drugs for ischemic stroke therapy have entered into clinical trials. Most of basic and clinical researches have showed promising results in ischemic stroke therapy. This review mainly summarizes the progress of research during the period of Twelfth Five-Year Plan for National Economic and Social Development on treatment of ischemic stroke, including omics technologies, gene therapy, microRNA (miRNA interference and stem cell therapy. Stem cell therapy has shown great potential since many clinical trials have been completed or are ongoing. The development and mutual transformation of basic and clinical research will provide valuable and comprehensive information for the precise treatment of ischemic stroke.

  2. Basic research on nuclear track microfilters for gas separation

    CERN Document Server

    Sudowe, R; Ensinger, W; Vetter, J; Penzhorn, R D; Brandt, R

    1999-01-01

    Basic research on nuclear track microfilters, NTMF, made from the polyimide foil UPILEX, has been carried out to investigate the possible use of NTMF for gas separation in an environment containing large amounts of tritium. NTMF with a pore diameter as low as 0.1 mu m have been etched and metal replicas of the pores have been produced to determine the pore shape. An experimental setup for determining the separation factor of a NTMF for a given gas mixture has been constructed, and first experiments have been carried out.

  3. Using mixed methods research in medical education: basic guidelines for researchers.

    Science.gov (United States)

    Schifferdecker, Karen E; Reed, Virginia A

    2009-07-01

    Mixed methods research involves the collection, analysis and integration of both qualitative and quantitative data in a single study. The benefits of a mixed methods approach are particularly evident when studying new questions or complex initiatives and interactions, which is often the case in medical education research. Basic guidelines for when to use mixed methods research and how to design a mixed methods study in medical education research are not readily available. The purpose of this paper is to remedy that situation by providing an overview of mixed methods research, research design models relevant for medical education research, examples of each research design model in medical education research, and basic guidelines for medical education researchers interested in mixed methods research. Mixed methods may prove superior in increasing the integrity and applicability of findings when studying new or complex initiatives and interactions in medical education research. They deserve an increased presence and recognition in medical education research.

  4. Adaptive fractionation therapy: I. Basic concept and strategy

    International Nuclear Information System (INIS)

    Lu Weiguo; Chen Mingli; Chen Quan; Ruchala, Kenneth; Olivera, Gustavo

    2008-01-01

    Radiotherapy is fractionized to increase the therapeutic ratio. Fractionation in conventional treatment is determined as part of the prescription, and a fixed fraction size is used for the whole course of treatment. Due to patients' day-to-day variations on the relative distance between the tumor and the organs at risk (OAR), a better therapeutic ratio may be attained by using an adaptive fraction size. Intuitively, we want to use a larger fraction size when OAR and the tumor are far apart and a smaller fraction size when OAR and the tumor are close to each other. The concept and strategies of adaptive fractionation therapy (AFT) are introduced in this paper. AFT is an on-line adaptive technique that utilizes the variations of internal structures to get optimal OAR sparing. Changes of internal structures are classified as different configurations according to their feasibility to the radiation delivery. A priori knowledge is used to describe the probability distribution of these configurations. On-line processes include identifying the configuration via daily image guidance and optimizing the current fraction size. The optimization is modeled as a dynamic linear programming problem so that at the end of the treatment course, the tumor receives the same planned dose while OAR receives less dose than the regular fractionation delivery. Extensive simulations, which include thousands of treatment courses with each course consisting of 40 fractions, are used to test the efficiency and robustness of the presented technique. The gains of OAR sparing depend on the variations on configurations and the bounds of the fraction size. The larger the variations and the looser the bounds are, the larger the gains will be. Compared to the conventional fractionation technique with 2 Gy/fraction in 40 fractions, for a 20% variation on tumor-OAR configurations and [1 Gy, 3 Gy] fraction size bounds, the cumulative OAR dose with adaptive fractionation is 3-8 Gy, or 7-20% less than that

  5. Basic research on flue gas smoke treatment by electron beam

    International Nuclear Information System (INIS)

    Namba, Hideki

    1995-01-01

    Recently, accompanying the increase of the use of fossil fuel, the environment destruction due to the sulfur oxides and nitrogen oxides contained in combustion smoke has become a serious problem. The development of flue gas smoke treatment technology by using electron beam was started in Japan, and attention has been paid worldwide as the promising dry type simultaneous desulfurizing and denitrating process. In this process, by adding ammonia to smoke, and irradiating electron beam on it, ammonium nitrate and ammonium sulfate are formed. As to the reaction mechanism of denitration and desulfurization, radical formation, radical reaction, denitration mechanism, desulfurization mechanism, the particle size distribution of the formed aerosol, the amounts of denitration and desulfurization by electron beam smoke treatment process, the improvement of the denitration efficiency by multi-stage irradiation method and the improvement of the desulfurization rate by low temperature irradiation, and the basic test toward the pilot test are explained. The basic research for putting this system to practical use was carried out jointly by Japan Atomic Energy Research Institute, Chubu Electric Power Co., Inc., and Ebara Seisakusho for standard coal burning smoke in Japan. The verifying test at the pilot plant in Shinnagoya Thermal Power Station was carried out, and it was verified that this process can be used practically for treating coal-burning smoke. (K.I.)

  6. Basic statistical tools in research and data analysis

    Directory of Open Access Journals (Sweden)

    Zulfiqar Ali

    2016-01-01

    Full Text Available Statistical methods involved in carrying out a study include planning, designing, collecting data, analysing, drawing meaningful interpretation and reporting of the research findings. The statistical analysis gives meaning to the meaningless numbers, thereby breathing life into a lifeless data. The results and inferences are precise only if proper statistical tests are used. This article will try to acquaint the reader with the basic research tools that are utilised while conducting various studies. The article covers a brief outline of the variables, an understanding of quantitative and qualitative variables and the measures of central tendency. An idea of the sample size estimation, power analysis and the statistical errors is given. Finally, there is a summary of parametric and non-parametric tests used for data analysis.

  7. BASIC

    DEFF Research Database (Denmark)

    Hansen, Pelle Guldborg; Schmidt, Karsten

    2017-01-01

    De sidste 10 år har vi været vidner til opkomsten af et nyt evidensbaseret policy paradigme, Behavioural Public Policy (BPP), der søger at integrere teoretiske og metodiske indsigter fra adfærdsvidenskaberne i offentlig politikudvikling. Arbejdet med BPP har dog båret præg af, at være usystematisk...... BPP. Tilgangen består dels af den overordnede proces-model BASIC og dels af et iboende framework, ABCD, der er en model for systematisk adfærdsanalyse, udvikling, test og implementering af adfærdsrettede løsningskoncepter. Den samlede model gør det muligt for forskere såvel som offentligt ansatte...

  8. Bling My Research! A Mock Grant Panel Activity Illustrating the Importance of Basic Research

    Science.gov (United States)

    Leander, Celeste A.; Whitton, Jeannette

    2010-01-01

    First-year university students have misconceptions about the source and dynamics of publicly funded research money. We designed an activity in which students take part in a mock grant panel. The results indicated a strong tendency toward student funding of applied medical research at the expense of basic research. Exposure to a few examples of…

  9. Information center as a link between basic and applied research

    International Nuclear Information System (INIS)

    Pearlstein, S.

    1976-01-01

    The National Neutron Cross Section Center (NNCSC) concerns itself with neutron physics information of a basic and applied nature. Computerized files of bibliography to the neutron physics literature, and of experimental and evaluated neutron data are maintained. The NNCSC coordinates a national effort, the Cross Section Evaluation Working Group (CSEWG) with participants from government, private, and academic institutions, to establish a computerized reference data base Evaluated Nuclear Data File (ENDF/B) for national programs. The ENDF/B is useful to basic research because it contains recommended values based on the best available measurements and is often used as reference data for normalization and analysis of experiments. For applied use the reference data are extended through nuclear model calculations or nuclear systematics to include all data of interest with standardized processing codes facilitating the use of ENDF/B in certain types of computations. Initially the main application of ENDF/B was power reactor and shield design and only neutron data were evaluated but due to the fact that for many applications both neutron and nonneutron data are required, ENDF/B has been extended in scope to include radioactive decay data and radiation spectra for the burnup and after decay heat of fission products and photon interaction data for gamma ray transport calculations. Cooperation with other centers takes place both nationally and internationally

  10. Basic research on human reliability in nuclear power plants

    International Nuclear Information System (INIS)

    Zhang Li; Deng Zhiliang

    1996-10-01

    Human reliability in nuclear power plants is one of key factors in nuclear safety and economic operation. According to cognitive science, behaviour theory and ergonomic and on the bases of human cognitive behaviour characteristics, performance shaping factors, human error mechanisms and organization management, the project systematically studied the human reliability in nuclear power plant systems, established the basic theory and methods for analyzing human factor accidents and suggested feasible approaches and countermeasures for precaution against human factor accidents and improving human reliability. The achievement has been applied in operation departments, management departments and scientific research institutions of nuclear power, and has produced guiding significance and practical value to design, operation and management in nuclear power plants. (11 refs.)

  11. Bridging basic science and clinical research: the EASL Monothematic Conference on Translational Research in Viral Hepatitis.

    Science.gov (United States)

    Boettler, Tobias; Moradpour, Darius; Thimme, Robert; Zoulim, Fabien

    2014-09-01

    The EASL Monothematic Conference on Translational Research in Viral Hepatitis brought together a group of leading scientists and clinicians working on both, basic and clinical aspects of viral hepatitis, thereby building bridges from bench to bedside. This report recapitulates the presentations and discussions at the conference held in Lyon, France on November 29-30, 2013. In recent years, great advances have been made in the field of viral hepatitis, particularly in hepatitis C virus (HCV) infection. The identification of IL28B genetic polymorphisms as a major determinant for spontaneous and treatment-induced HCV clearance was a seminal discovery. Currently, hepatologists are at the doorstep of even greater advances, with the advent of a wealth of directly acting antivirals (DAAs) against HCV. Indeed, promising results have accumulated over the last months and few years, showing sustained virological response (SVR) rates of up to 100% with interferon-free DAA combination therapies. Thus, less than 25 years after its identification, HCV infection may soon be curable in the vast majority of patients, highlighting the great success of HCV research over the last decades. However, viral hepatitis and its clinical complications such as liver cirrhosis and hepatocellular carcinoma (HCC) remain major global challenges. New therapeutic strategies to tackle hepatitis B virus (HBV) and hepatitis D virus (HDV) infection are needed, as current therapies have undeniable limitations. Nucleoside/nucleotide analogues (NUC) can efficiently control HBV replication and reduce or even reverse liver damage. However, these drugs have to be given for indefinite periods in most patients to maintain virological and biochemical responses. Although sustained responses off treatment can be achieved by treatment with (pegylated) interferon-α, only about 10-30% of patients effectively resolve chronic hepatitis B. It was the goal of this conference to review the progress made over the last

  12. Polymer materials basic research needs for energy applications

    Energy Technology Data Exchange (ETDEWEB)

    Macknight, W.J.; Baer, E.; Nelson, R.D. (eds.)

    1978-08-01

    The larger field covered in the workshop consists of (1) synthesis and characterization, (2) physical chemistry, (3) physics, and (4) engineering. Polymeric materials are properly regarded as new materials in their own right, not as replacements for existing materials. As such they need to be studied to understand the properties which are unique to them by virtue of their particular molecular structures. Technological applications will rationally follow from such studies. It is the objective of this report to point out basic research needs in polymer materials related to energy. The development of sophisticated instrumentation makes the task of molecular characterization possible on a level hitherto unattainable. Many of these instruments because of their size and complexity must of necessity be located at the DOE National Laboratories. The importance of personnel trained in the polymer field located at these facilities is emphasized. In the past there has been relatively little concerted polymer research within the energy community. This report attempts to describe the present situation and point out some needs and future research directions. (GHT)

  13. Investing in lean to improve basic capabilities: A strategy for system supply?

    Directory of Open Access Journals (Sweden)

    Inga-Lill Carlsson

    2017-04-01

    Full Text Available Purpose: This paper describes the perceived effects of implementing lean production in a Swedish SME contract manufacturer. Especially focused are the effects on, and possible trade-offs between, cost-efficiency and flexibility. Design/methodology/approach: SME suppliers need basic capabilities of qualitative production performance which may then be stepping-stones to develop more system supplier capabilities for added customer value: leadership to manage systems and processes, SCM, communications and relations management. Development of stable production processes is seen as a way to reach stable basic performance, efficient and with higher resource utilization. Quality is a precursor to delivery performance as well as to cost reduction and flexibility. This is a longitudinal single case study of a SME supplier striving to become a system supplier. Two main sources of data collection are used: interviews and the main author’s presence as employee and business developer, participating in and following up the ongoing change process. Findings: Two specific findings appeared: (1 An initial effect was an important “eye-opener” for the balance between cost efficiency and flexibility in the organization. (2 Process orientation, as the basis of both lean and agile approaches, allows many improvements without any conflicts or trade-offs between these two goals. Stability in the production leads to increased controllability, initially resulting in both higher cost-efficiency and higher flexibility. As the organization develops however, strategic considerations relating to the chosen market strategy might occur: cost leadership or differentiation.    Research limitations/implications: These results reflect the experiences of one SME supplier and further studies are needed for generalizability. Originality/value: The study increases the understanding of how a SME may develop stable processes in its different supplier-customer contexts. The study

  14. Research by design - a research strategy

    DEFF Research Database (Denmark)

    Hauberg, Jørgen

    2011-01-01

    Abstract The idea of an expressive component in research is important to the architectural industry. The expressive element - the possibility of expressing the qualitative aspects of the world and adding something new to the existing through experiments and proposals - is characteristic....... Research is ‘coloured’ by traditions and professions, and research in architecture should be coloured too, taking in consideration that the practise of architects stretch from natural science and sociology to art, and because the most important way in which the architect achieves new cognition is through...... for the field. All research environments, in the science tradition and in the humanities, have their characteristics. On the one hand, they live up to certain common scientific and methodological criteria - originality and transparency - on the other hand they have different practices, using different methods...

  15. Research by Design - a research strategy

    DEFF Research Database (Denmark)

    Hauberg, Jørgen

    2011-01-01

    Abstract The idea of an expressive component in research is important to the architectural industry. The expressive element - the possibility of expressing the qualitative aspects of the world and adding something new to the existing through experiments and proposals - is characteristic...... methods. Research is ‘coloured’ by traditions and professions, and research in architecture should be coloured too, taking into consideration that the practice of architects stretches from natural science and sociology to art and that the most important way in which the architect achieves new cognition...... for the field. All research environments, in the science tradition and in the humanities, have their characteristics. On the one hand, they live up to certain common scientific and methodological criteria - originality and transparency – and on the other hand, they have different practices, using different...

  16. Science Serving the Nation: The Impact of Basic Research

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2012-01-01

    Impacts: The BES program supports basic research that underpins a broad range of energy technologies. Research in materials sciences and engineering leads to the development of materials that improve the efficiency, economy, environmental acceptability, and safety of energy generation, conversion, transmission, storage, and use. For example, advances in superconductivity have been introduced commercially in a number of demonstration projects around the country. Improvements in alloy design for high temperature applications are used in commercial furnaces and in green technologies such as lead-free solder. Research in chemistry has led to advances such as efficient combustion systems with reduced emissions of pollutants; new solar photoconversion processes; improved catalysts for the production of fuels and chemicals; and better separations and analytical methods for applications in energy processes, environmental remediation, and waste management. Research in geosciences results in advanced monitoring and measurement techniques for reservoir definition and an understanding of the fluid dynamics of complex fluids through porous and fractured subsurface rock. Research in the molecular and biochemical nature of photosynthesis aids the development of solar photo-energy conversion. The BES program also plays a major role in enabling the nanoscale revolution. The importance of nanoscience to future energy technologies is clearly reflected by the fact that all of the elementary steps of energy conversion (e.g., charge transfer, molecular rearrangement, and chemical reactions) take place on the nanoscale. The development of new nanoscale materials, as well as the methods to characterize, manipulate, and assemble them, create an entirely new paradigm for developing new and revolutionary energy technologies.

  17. Foresight and strategy in national research councils and research programmes

    DEFF Research Database (Denmark)

    Andersen, Per Dannemand; Borup, Mads

    2009-01-01

    This paper addresses the issue of foresight and strategy processes of national research councils and research programmes. It is based on a study of strategy processes in national research councils and programmes and the challenges faced by their strategy activities. We analysed the strategy...... processes of two organisations: the Danish Technical Research Council and the Danish Energy Research Programme. We analysed the mechanisms of the strategy processes and studied the actors involved. The actors’ understanding of strategy was also included in the analysis. Based on these analyses we argue...... that the impact of foresight exercises can be improved if we have a better understanding of the traditions and new challenges faced by the research councils. We also argue that a more formal use of foresight elements might improve the legitimacy and impact of the strategic considerations of research councils...

  18. KEEP Language Research Strategy. Technical Report #14.

    Science.gov (United States)

    Tharp, Roland G.; Gallimore, Ronald

    This paper outlines the strategies of Kamehameha Early Education Program (KEEP) language research, and briefly reviews the findings through Spring 1974. A major research emphasis has been placed on the assessment of Standard English comptence of Hawaii school children. (CM)

  19. Basic researches for advancement of man-machine systems

    International Nuclear Information System (INIS)

    Yoshikawa, Hidekazu

    1994-01-01

    The historical development of plant instrumentation and control system accompanying the introduction of automation is shown by the example of nuclear power plants. It is explained, and the change in the role of operators in the man-machine system is mentioned. Human errors are the serious problem in various fields, and automation resolves it. But complex systems also caused various disasters due to the relation of men and machines. The problem of human factors in high risk system automation is considered as the heightening of reliability and the reduction of burden on workers by decreasing human participation, and the increase of the risk of large accidents due to the lowering of reliability of human elements and the strengthening of the training of workers. Human model and the framework of human error analysis, the development of the system for man-machine system design and information analysis and evaluation, the significance of physiological index measurement and the perspective of the application, the analysis of the behavior of subjects in the abnormality diagnosis experiment using a plant simulator, and the development to the research on mutual adaptation interface are discussed. In this paper, the problem of human factors in system safety, that technical advancement brings about is examined, and the basic research on the advancement of man-machine systems by the author is reported. (K.I.)

  20. Basic Requirements for Systems Software Research and Development

    Science.gov (United States)

    Kuszmaul, Chris; Nitzberg, Bill

    1996-01-01

    Our success over the past ten years evaluating and developing advanced computing technologies has been due to a simple research and development (R/D) model. Our model has three phases: (a) evaluating the state-of-the-art, (b) identifying problems and creating innovations, and (c) developing solutions, improving the state- of-the-art. This cycle has four basic requirements: a large production testbed with real users, a diverse collection of state-of-the-art hardware, facilities for evalua- tion of emerging technologies and development of innovations, and control over system management on these testbeds. Future research will be irrelevant and future products will not work if any of these requirements is eliminated. In order to retain our effectiveness, the numerical aerospace simulator (NAS) must replace out-of-date production testbeds in as timely a fashion as possible, and cannot afford to ignore innovative designs such as new distributed shared memory machines, clustered commodity-based computers, and multi-threaded architectures.

  1. The Society of Radiographers' research strategy

    International Nuclear Information System (INIS)

    Reeves, Pauline; Wright, Caroline; Shelley, Susan; Williams, Pat

    2004-01-01

    A research strategy for the Radiography (London 1995) profession was approved by the Council of the Society and College of Radiographers at the end of 2001.This paper discusses the formulation of that strategy, including the factors that lay behind its development. The recommendations of the strategy are then addressed one by one, together with a review as to their implementation by the College's Research Group

  2. An Emerging Strategy of "Direct" Research.

    Science.gov (United States)

    Mintzberg, Henry

    1979-01-01

    Discusses seven basic themes that underlie the author's "direct research" activities. These themes include reliance on research based on description and induction instead of prescription and deduction, and the measurement of many elements in real settings, supported by anecdote, instead of few variables in perceptual terms from a…

  3. Basic Research in HIV vaccinology is hampered by reductionist thinking

    Directory of Open Access Journals (Sweden)

    Marc H V Van Regenmortel

    2012-07-01

    Full Text Available This review describes the structure-based reverse vaccinology approach aimed at developing vaccine immunogens capable of inducing antibodies that broadly neutralize HIV-1. Some basic principles of protein immunochemistry are reviewed and the implications of the extensive polyspecificity of antibodies for vaccine development are underlined. Although it is natural for investigators to want to know the cause of an effective immunological intervention, the classic notion of causality is shown to have little explanatory value for a system as complex as the immune system, where any observed effect always results from many interactions between a large number of components. Causal explanations are reductive because a single factor is singled out for attention and given undue explanatory weight on its own. Other examples of the negative impact of reductionist thinking on HIV vaccine development are discussed. These include 1 the failure to distinguish between the chemical nature of antigenicity and the biological nature of immunogenicity, 2 the belief that when an HIV-1 epitope is reconstructed by rational design to better fit a neutralizing Mab, this will produce an immunogen able to elicit Abs with the same neutralizing capacity as the Ab used as template for designing the antigen 3 the belief that protection against infection can be analysed at the level of individual molecular interactions although it has meaning only at the level of an entire organism.The numerous unsuccessful strategies that have been used to design HIV-1 vaccine immunogens are described and it is suggested that the convergence of so many negative experimental results, justifies the conclusion that reverse vaccinology is unlikely to lead to the development of a preventive HIV-1 vaccine. Immune correlates of protection in vaccinees have not yet been identified because this will become feasible only retrospectively once an effective vaccine exists.

  4. Decision strategy research: system analysis

    International Nuclear Information System (INIS)

    Carle, B.

    2000-01-01

    The objective of SCK-CEN's R and D programme on decision strategies is (1) to develop theories, methods and software tools which help decision makers shape, analyse and understand their decisions; (2) to study group processes in decision making; (3) to apply theories, methods and tools in a context related to nuclear emergency preparedness and more generally to support in a context dealing with ionising radiation; (4) to increase SCK-CEN's knowledge on general emergency preparedness and to introduce SCK-CEN staff to computer supported decision techniques. Ongoing R and D has two components: (1) the study of the use of information and knowledge transfer in group decision processes, and more specific studying important factors when computers are used as information source and communication tool; and (2) the study of preference modelling individually and during group decision processes. Principal achievements in 1999 are described

  5. Decision strategy research: system analysis

    Energy Technology Data Exchange (ETDEWEB)

    Carle, B

    2000-07-01

    The objective of SCK-CEN's R and D programme on decision strategies is (1) to develop theories, methods and software tools which help decision makers shape, analyse and understand their decisions; (2) to study group processes in decision making; (3) to apply theories, methods and tools in a context related to nuclear emergency preparedness and more generally to support in a context dealing with ionising radiation; (4) to increase SCK-CEN's knowledge on general emergency preparedness and to introduce SCK-CEN staff to computer supported decision techniques. Ongoing R and D has two components: (1) the study of the use of information and knowledge transfer in group decision processes, and more specific studying important factors when computers are used as information source and communication tool; and (2) the study of preference modelling individually and during group decision processes. Principal achievements in 1999 are described.

  6. Superconductors at the nanoscale. From basic research to applications

    Energy Technology Data Exchange (ETDEWEB)

    Woerdenweber, Roger [Forschungszentrum Juelich GmbH (Germany). Peter Gruenberg Inst.; Moshchalkov, Victor [KU Leuven (Belgium). Inst. for Nanoscale Physics and Chemistry; Bending, Simon [Bath Univ. (United Kingdom). School of Physics; Tafuri, Francesco (ed.) [Seconda Univ. di Napoli, Aversa (Italy)

    2017-07-01

    By covering theory, design, and fabrication of nanostructured superconducting materials, this monograph is an invaluable resource for research and development. This book contains the following chapters: Tutorial on nanostructured superconductors; Imaging vortices in superconductors: from the atomic scale to macroscopic distances; Probing vortex dynamics on a single vortex level by scanning ac-susceptibility microscopy; STM studies of vortex cores in strongly confined nanoscale superconductors; Type-1.5 superconductivity; Direct visualization of vortex patterns in superconductors with competing vortex-vortex interactions; Vortex dynamics in nanofabricated chemical solution deposition high-temperature superconducting films; Artificial pinning sites and their applications; Vortices at microwave frequencies; Physics and operation of superconducting single-photon devices; Josephson and charging effect in mesoscopic superconducting devices; NanoSQUIDs: Basics and recent advances; Bi{sub 2}Sr{sub 2}CaCu{sub 2}O{sub 8} intrinsic Josephson junction stacks as emitters of terahertz radiation; Interference phenomena in superconductor-ferromagnet hybrids; Spin-orbit interactions, spin currents, and magnetization dynamics in superconductor/ferromagnet hybrids; Superconductor/ferromagnet hybrids.

  7. Basic research of neutron radiography using cold neutron beam

    International Nuclear Information System (INIS)

    Oda, Masahiro; Tamaki, Masayoshi; Tasaka, Kanji

    1995-01-01

    As the result of demanding high quality images, now the nuclear reactors which can supply stably intense neutron beam have become the most general neutron source for radiography. For the purpose, mostly thermal neutrons have been used, but it is indispensable to use other neutrons than thermal neutrons for advancing neutron radiography technology and expanding the application fields. The radiography using cold neutrons is most behind in the development because the suitable neutron source was not available in Japan. The neutron sources for exclusively obtaining intense cold neutron beam were installed in the Kyoto University reactor in 1986 and in the JRR-3M of Japan Atomic Energy Research Institute in 1991. Basically as neutron energy lowers, the cross section of substances increases. In certain crystalline substances, the Bragg cutoff arises. The removal of scattered neutrons, the measurement of parallelism of beam and the relation of the thickness of objects with the transmissivity of cold neutrons are described. The imaging by TV method and the cold neutron CT in the CNRF and the simplified neutron CT by film method are reported. (K.I.)

  8. 20 CFR 669.310 - What are the basic components of an NFJP service delivery strategy?

    Science.gov (United States)

    2010-04-01

    ... include: (a) A customer-centered case management approach; (b) The provision of workforce investment... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What are the basic components of an NFJP service delivery strategy? 669.310 Section 669.310 Employees' Benefits EMPLOYMENT AND TRAINING...

  9. Strategies for Financing Universal Basic Education for Sustainable National Development in Nigeria

    Science.gov (United States)

    Abdullahi, N. J. K.; Abdulkareem, A. Y.

    2017-01-01

    This study investigated strategies of financing universal basic education for sustainable national development by school managers in North-Central Zone, Nigeria. Specifically the purpose was to determine the relationship between commercial based income and sustainable national development as well as to examine the relationship between agricultural…

  10. Improving the basic skills of teaching mathematics through learning with search-solve-create-share strategy

    Science.gov (United States)

    Rahayu, D. V.; Kusumah, Y. S.; Darhim

    2018-05-01

    This study examined to see the improvement of prospective teachers’ basic skills of teaching mathematics through search-solve-create-share learning strategy based on overall and Mathematical Prior Knowledge (MPK) and interaction of both. Quasi experiments with the design of this experimental-non-equivalent control group design involved 67 students at the mathematics program of STKIP Garut. The instrument used in this study included pre-test and post-test. The result of this study showed that: (1) The improvement and achievement of the basic skills of teaching mathematics of the prospective teachers who get the learning of search-solve-create-share strategy is better than the improvement and achievement of the prospective teachers who get the conventional learning as a whole and based on MPK; (2) There is no interaction between the learning used and MPK on improving and achieving basic skills of teaching mathematics.

  11. Marketing Capability in Strategy Research

    DEFF Research Database (Denmark)

    Ritter, Thomas; Distel, Andreas Philipp

    Following the call for a demand-side perspective of strategic management (e.g., Priem et al., 2012), a firm’s marketing capability, i.e. its ability to interact with down-stream stakeholders, becomes a pivotal element in explaining a firm’s competitiveness. While marketing capability is recognized...... in the strategic management literature as an important driver of firm performance, our review of 86 articles reveals a lack of a generally accepted definition of marketing capability, a lack of a common conceptualization as well as differences in the measurement of marketing capability. In order to build a common...... ground for advancing marketing capability research and thus supporting the demand-side perspective in strategic management, we develop an integrative framework to explain the differences and propose a research agenda for developing the field....

  12. Poultry studies and anthropological research strategies

    International Nuclear Information System (INIS)

    Whyte, M.

    2002-01-01

    Poultry are not simply birds; they are also a human creation, a social and cultural practice. The human element is the justification for an anthropology of poultry. Such an anthropology combines the objective research strategies familiar to the natural sciences with what is often called 'subjective' or qualitative research. In the study of poultry management, it is important that both research strategies focus on differences and variation. The subjective approach is particularly useful in identifying and understanding how the motivations and strategies of local actors are dependent on the social positions, which they occupy in their specific societies. (author)

  13. Time management strategies for research productivity.

    Science.gov (United States)

    Chase, Jo-Ana D; Topp, Robert; Smith, Carol E; Cohen, Marlene Z; Fahrenwald, Nancy; Zerwic, Julie J; Benefield, Lazelle E; Anderson, Cindy M; Conn, Vicki S

    2013-02-01

    Researchers function in a complex environment and carry multiple role responsibilities. This environment is prone to various distractions that can derail productivity and decrease efficiency. Effective time management allows researchers to maintain focus on their work, contributing to research productivity. Thus, improving time management skills is essential to developing and sustaining a successful program of research. This article presents time management strategies addressing behaviors surrounding time assessment, planning, and monitoring. Herein, the Western Journal of Nursing Research editorial board recommends strategies to enhance time management, including setting realistic goals, prioritizing, and optimizing planning. Involving a team, problem-solving barriers, and early management of potential distractions can facilitate maintaining focus on a research program. Continually evaluating the effectiveness of time management strategies allows researchers to identify areas of improvement and recognize progress.

  14. Basic research for developing the quantitative neutron radiography

    International Nuclear Information System (INIS)

    Tamaki, Masayoshi; Ikeda, Yasushi; Ohkubo, Kohei; Tasaka, Kanji; Yoneda, Kenji; Fujine, Shigenori.

    1992-01-01

    This investigation concerns the basic research and development on quantitative neutron radiography by using a honeycomb collimator which reduces the effect due to scattered neutrons in objective matter. On the observation of the hydrogenate materials such as metal hydrides, water and hydrocarbons by neutron radiography, scattered neutrons from these objectives make the quantitativeness of the neutron radiographic image lower grade. In order to improve the quantitativeness of the image, a honeycomb collimator, which is a honeycomb structure of neutron absorbing material, was introduced to the conventional neutron radiography system. By setting the neutron-absorbing honeycomb collimator between objective and imaging system, neutrons scattered in the objective were absorbed by the honeycomb material and attenuated before coming to the imaging system, but neutrons which were transmitted the objective sample without any interaction reached the imaging system and formed the image of the sample. As the image by purely transmitted neutrons is intrinsic due to the neutronic character of the sample, the image data give the quantitative information. In the present experiment, aluminum honeycomb which was coated with boron nitride was prepared and used in order to image the standard stepwise samples for the evaluation of the quantitative grade of the newly proposed neutron radiography method. From the comparison between macroscopic total cross section and the attenuation coefficient of the thermal neutron for aluminum, copper and hydrocarbons, it was confirmed that they were fairly consistent each other. It can be concluded that the newly proposed neutron radiography method using the neutron-absorbing honeycomb collimator for the elimination of the scattered neutrons improves remarkably the quantitativeness of the neutron radiography technique. (author)

  15. Novel strategies for sedentary behavior research.

    Science.gov (United States)

    Rosenberg, Dori E; Lee, I-Min; Young, Deborah Rohm; Prohaska, Thomas R; Owen, Neville; Buchner, David M

    2015-06-01

    This article reports on the "Novel Strategies for Sedentary Behavior Research" session of the Sedentary Behavior: Identifying Research Priorities workshop. The purpose of this session of the workshop were to propose strategies for accomplishing a research agenda in dealing with sedentary behavior and to consider research priorities for people at high risk for excess sedentary behavior. The four major recommendations from this workshop were as follows: 1) To add repeated objective measures of physical activity and sedentary behavior to existing cohort studies and standardize approaches to measurement and analysis. Epidemiologic studies will be the most efficient design for addressing some research questions. 2) To increase research efficiency, consider the advantages of a network of connected research studies and health systems. Advantages include access to existing data in electronic health records. 3) To carefully select a variety of high-risk study populations and preplan collaboration among studies in intervention research. This strategy can efficiently address the breadth of issues in sedentary behavior research. 4) To include comparative effectiveness designs and pure environmental interventions in intervention research. This strategy facilitates and enhances translation of interventions into practice.

  16. Cluster: Drafting. Course: Basic Technical Drafting. Research Project.

    Science.gov (United States)

    Sanford - Lee County Schools, NC.

    The set of six units is designed for use with an instructor in basic technical drafting and is also keyed to other texts. Each unit contains several task packages specifying prerequisites, rationale for learning, objectives, learning activities to be supervised by the instructor, and learning practice. The units cover: pictorial drawing; screw…

  17. Citation analysis may severely underestimate the impact of clinical research as compared to basic research.

    Science.gov (United States)

    van Eck, Nees Jan; Waltman, Ludo; van Raan, Anthony F J; Klautz, Robert J M; Peul, Wilco C

    2013-01-01

    Citation analysis has become an important tool for research performance assessment in the medical sciences. However, different areas of medical research may have considerably different citation practices, even within the same medical field. Because of this, it is unclear to what extent citation-based bibliometric indicators allow for valid comparisons between research units active in different areas of medical research. A visualization methodology is introduced that reveals differences in citation practices between medical research areas. The methodology extracts terms from the titles and abstracts of a large collection of publications and uses these terms to visualize the structure of a medical field and to indicate how research areas within this field differ from each other in their average citation impact. Visualizations are provided for 32 medical fields, defined based on journal subject categories in the Web of Science database. The analysis focuses on three fields: Cardiac & cardiovascular systems, Clinical neurology, and Surgery. In each of these fields, there turn out to be large differences in citation practices between research areas. Low-impact research areas tend to focus on clinical intervention research, while high-impact research areas are often more oriented on basic and diagnostic research. Popular bibliometric indicators, such as the h-index and the impact factor, do not correct for differences in citation practices between medical fields. These indicators therefore cannot be used to make accurate between-field comparisons. More sophisticated bibliometric indicators do correct for field differences but still fail to take into account within-field heterogeneity in citation practices. As a consequence, the citation impact of clinical intervention research may be substantially underestimated in comparison with basic and diagnostic research.

  18. International Journal of Basic, Applied and Innovative Research

    African Journals Online (AJOL)

    2014-12-31

    Dec 31, 2014 ... This study examined the strategies in business education and its role in ... skills necessary for the management of our nation's abundant ..... increasing teacher's willingness to integrate technology for classroom teaching.

  19. Research Strategies in European Union Studies

    DEFF Research Database (Denmark)

    Manners, Ian James; Lynggaard, Kennet; Löfgren, Karl

    2015-01-01

    The contributing chapters of this book all illustrate the richness and diversity of problem-driven research in EU studies. This concluding chapter draws together the insights of this rich diversity in order to move the study of research strategies beyond the dichotomies of the past towards a new...... agenda for research on Europe. The crisis gripping the EU in the 21st century is not just an economic crisis, it is a crisis of belief in the EU. Research on the EU is deeply implicated in this crisis, not least because of the questions it does not ask, but also because of the pereceived weakness...... of demonstrating the methods and evidence used. A new agenda for research on Europe needs to acknowledge these weaknesses of the past and move beyond dichotomies towards greater awareness and openesss of the importance of research strategies, designs and methods....

  20. U.S. Army Research Institute Program in Basic Research-FY 2010

    Science.gov (United States)

    2010-11-01

    and solutions. The eLearning Developers Journal. Retrieved March 09, 2009, from http://www.elearningguild.com/pdf/2/071403MGT-L.pdf Mobley, W. H...data on social trends and social changes in the global system, American society, and the Army, including changes in the demography of the American...next six months. Contributions to Basic Research This project contributes to our understanding of how changes in global and societal systems

  1. Introduction to basic molecular biologic techniques for molecular imaging researches

    International Nuclear Information System (INIS)

    Kang, Joo Hyun

    2004-01-01

    Molecular imaging is a rapidly growing field due to the advances in molecular biology and imaging technologies. With the introduction of imaging reporter genes into the cell, diverse cellular processes can be monitored, quantified and imaged non-invasively in vivo. These processes include the gene expression, protein-protein interactions, signal transduction pathways, and monitoring of cells such as cancer cells, immune cells, and stem cells. In the near future, molecular imaging analysis will allow us to observe the incipience and progression of the disease. These will make us easier to give a diagnosis in the early stage of intractable diseases such as cancer, neuro-degenerative disease, and immunological disorders. Additionally, molecular imaging method will be a valuable tool for the real-time evaluation of cells in molecular biology and the basic biological studies. As newer and more powerful molecular imaging tools become available, it will be necessary to corporate clinicians, molecular biologists and biochemists for the planning, interpretation, and application of these techniques to their fullest potential. In order for such a multidisciplinary team to be effective, it is essential that a common understanding of basic biochemical and molecular biologic techniques is achieved. Basic molecular techniques for molecular imaging methods are presented in this paper

  2. Basic Research Needs for Advanced Nuclear Systems. Report of the Basic Energy Sciences Workshop on Basic Research Needs for Advanced Nuclear Energy Systems, July 31-August 3, 2006

    Energy Technology Data Exchange (ETDEWEB)

    Roberto, J.; Diaz de la Rubia, T.; Gibala, R.; Zinkle, S.; Miller, J.R.; Pimblott, S.; Burns, C.; Raymond, K.; Grimes, R.; Pasamehmetoglu, K.; Clark, S.; Ewing, R.; Wagner, A.; Yip, S.; Buchanan, M.; Crabtree, G.; Hemminger, J.; Poate, J.; Miller, J.C.; Edelstein, N.; Fitzsimmons, T.; Gruzalski, G.; Michaels, G.; Morss, L.; Peters, M.; Talamini, K.

    2006-10-01

    The global utilization of nuclear energy has come a long way from its humble beginnings in the first sustained nuclear reaction at the University of Chicago in 1942. Today, there are over 440 nuclear reactors in 31 countries producing approximately 16% of the electrical energy used worldwide. In the United States, 104 nuclear reactors currently provide 19% of electrical energy used nationally. The International Atomic Energy Agency projects significant growth in the utilization of nuclear power over the next several decades due to increasing demand for energy and environmental concerns related to emissions from fossil plants. There are 28 new nuclear plants currently under construction including 10 in China, 8 in India, and 4 in Russia. In the United States, there have been notifications to the Nuclear Regulatory Commission of intentions to apply for combined construction and operating licenses for 27 new units over the next decade. The projected growth in nuclear power has focused increasing attention on issues related to the permanent disposal of nuclear waste, the proliferation of nuclear weapons technologies and materials, and the sustainability of a once-through nuclear fuel cycle. In addition, the effective utilization of nuclear power will require continued improvements in nuclear technology, particularly related to safety and efficiency. In all of these areas, the performance of materials and chemical processes under extreme conditions is a limiting factor. The related basic research challenges represent some of the most demanding tests of our fundamental understanding of materials science and chemistry, and they provide significant opportunities for advancing basic science with broad impacts for nuclear reactor materials, fuels, waste forms, and separations techniques. Of particular importance is the role that new nanoscale characterization and computational tools can play in addressing these challenges. These tools, which include DOE synchrotron X

  3. Basic Research Needs for Advanced Nuclear Systems. Report of the Basic Energy Sciences Workshop on Basic Research Needs for Advanced Nuclear Energy Systems, July 31-August 3, 2006

    International Nuclear Information System (INIS)

    Roberto, J.; Diaz de la Rubia, T.; Gibala, R.; Zinkle, S.; Miller, J.R.; Pimblott, S.; Burns, C.; Raymond, K.; Grimes, R.; Pasamehmetoglu, K.; Clark, S.; Ewing, R.; Wagner, A.; Yip, S.; Buchanan, M.; Crabtree, G.; Hemminger, J.; Poate, J.; Miller, J.C.; Edelstein, N.; Fitzsimmons, T.; Gruzalski, G.; Michaels, G.; Morss, L.; Peters, M.; Talamini, K.

    2006-01-01

    The global utilization of nuclear energy has come a long way from its humble beginnings in the first sustained nuclear reaction at the University of Chicago in 1942. Today, there are over 440 nuclear reactors in 31 countries producing approximately 16% of the electrical energy used worldwide. In the United States, 104 nuclear reactors currently provide 19% of electrical energy used nationally. The International Atomic Energy Agency projects significant growth in the utilization of nuclear power over the next several decades due to increasing demand for energy and environmental concerns related to emissions from fossil plants. There are 28 new nuclear plants currently under construction including 10 in China, 8 in India, and 4 in Russia. In the United States, there have been notifications to the Nuclear Regulatory Commission of intentions to apply for combined construction and operating licenses for 27 new units over the next decade. The projected growth in nuclear power has focused increasing attention on issues related to the permanent disposal of nuclear waste, the proliferation of nuclear weapons technologies and materials, and the sustainability of a once-through nuclear fuel cycle. In addition, the effective utilization of nuclear power will require continued improvements in nuclear technology, particularly related to safety and efficiency. In all of these areas, the performance of materials and chemical processes under extreme conditions is a limiting factor. The related basic research challenges represent some of the most demanding tests of our fundamental understanding of materials science and chemistry, and they provide significant opportunities for advancing basic science with broad impacts for nuclear reactor materials, fuels, waste forms, and separations techniques. Of particular importance is the role that new nanoscale characterization and computational tools can play in addressing these challenges. These tools, which include DOE synchrotron X

  4. Basic materials research programs at the U.S. Air Force Office of Scientific Research

    International Nuclear Information System (INIS)

    Carlson, Herbert C.; Goretta, K.C.

    2006-01-01

    The Air Force Office of Scientific Research (AFOSR) annually sponsors approximately 5000 research scientists at 1000 universities and laboratories, generating about 10,000 Ph.D. graduates per decade, all expected to publish their basic research findings in peer-reviewed journals. After a brief introduction of the nature of AFOSR's support to basic research in the U.S. and international scientific communities, work it supports at the frontiers of materials science is highlighted. One focused research theme that drives our investment is the MEANS program. It begins with the end in mind; materials are designed with practicable manufacture as an explicit initial goal. AFOSR's broad research portfolio comprises many materials. Nanotechnology efforts include optical materials that reduce distortion to the scale of the nanoparticles themselves. Advances in semiconductors include breakthroughs in Group III nitrides, some of which emanated from Asia under sponsorship from AFOSR's Asian office. Advances in structural materials include those for use at ultra-high temperatures and self-healing composites. The growing role of high-performance computing in design and study of functional, biological, and structural materials is also discussed

  5. Strategy of formation and training for the basic units of cooperative production. Actions for their implementation

    Directory of Open Access Journals (Sweden)

    Iriadna Marín de León

    2014-06-01

    The implementation of the strategy of Formation and Training had great importance since applying the same one, they could get rich our cooperatives, of elements that contribute to the obtaining of a bigger level of efficiency and effectiveness of the human resources, given by the knowledge that they can acquire the same ones.   The article approaches the topics of Administration of human resources, formation and training theoretically, the elements of the functional strategy, and lastly a journey for the Cooperative Sector leaving of its emergence until specifying the characteristics of the Basic Units of Cooperative Production as part of the same one.   He is also carried out a valuation of the current situation as for Formation and Training of the human resources in the UBPC of the County of Pinar del Ro. This is made going to different diagnosis techniques. Later on they intend the actions that allow the implementation of this strategy.

  6. Strategies for fostering basic psychological needs support in high quality youth leadership programs.

    Science.gov (United States)

    Bean, Corliss; Harlow, Meghan; Kendellen, Kelsey

    2017-04-01

    Youth leadership programming has become an increasingly common context to foster basic psychological needs and promote youth development. The purpose of this qualitative study was to explore strategies involved in fostering youth needs support within six leadership programs. Two leaders and 30 youth participated in semi-structured interviews to better understand the strategies used to foster needs support. Findings revealed that leaders were able to foster a sense of relatedness among youth through building trusting adult-youth relationships and nurturing an inclusive environment. Maximizing choice and negotiating youth voice helped to foster youth's autonomy. Finally, creating a task-oriented climate and providing intentional opportunities for skill-building helped to foster youth's competence. Findings suggest that training for leaders is critical in understanding what, and how strategies should be employed to help foster youth needs support in leadership programming. Limitations and future directions are outlined. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Some frontiers of research in basic ruminant nutrition

    African Journals Online (AJOL)

    research on energy metabolism covers mechanisms of energy generation in anaerobes ..... by the action of ionophores would be at distinct disadvantage unless they could couple ...... industrial utilization of renewable resources. New research ...

  8. International Journal of Basic, Applied and Innovative Research *1 ...

    African Journals Online (AJOL)

    2013-12-31

    Dec 31, 2013 ... The research carried out in health education is holistic and all embracing. It may be qualitative, quantitative or mixed. While qualitative research is used when little or nothing is known about the subject, quantitative research is required when there are quantifiable variables to be measured. By implication ...

  9. Competence of matric physical science teachers in some basic problem-solving strategies

    Directory of Open Access Journals (Sweden)

    Mailoo Selvaratnam

    2011-01-01

    Full Text Available The National Curriculum Statement for matric physical science places strong emphasis on the development of critical thinking and reasoning abilities of pupils. The successful implementation of this curriculum therefore requires teachers who are competent in the cognitive (intellectual skills and strategies needed for learning science effectively. Testing of teachers’ competence in this aspect is therefore important. I therefore analysed teachers’ answers to questions that were carefully designed to test competence in some basic intellectual strategies that are important for problem solving in physical science courses. A total of 73 matric physical science teachers, from about 50 Dinaledi schools in the North West and KwaZulu-Natal provinces in South Africa, were tested in five intellectual strategies: clear representation of problems, identifying and focusing on the goal, identification and use of relevant principles, use of equations for deductions and proceeding step-by-step with the solution. The teachers’ competence was poor in all the intellectual strategies tested. About 60% (the average performance in all 13 questions used for testing of teachers tested were unable to solve the questions correctly. An important objective of the curriculum is the development of critical thinking, scientific reasoning and strategies of pupils. This study shows that the achievement of this objective will be seriously handicapped because of the lack of competence of many teachers in intellectual strategies. There is therefore a need to train teachers in order to increase their competence in this aspect.

  10. [Sampling in qualitative research: basic principles and some controversies].

    Science.gov (United States)

    Martínez-Salgado, Carolina

    2012-03-01

    This paper presents the rationale for the choice of participants in qualitative research in contrast with that of probability sampling principles in epidemiological research. For a better understanding of the differences, concepts of nomothetic and ideographic generalizability, as well as those of transferability and reflexivity, are proposed, Fundamentals of the main types of sampling commonly used in qualitative research, and the meaning of the concept of saturation are mentioned. Finally, some reflections on the controversies that have arisen in recent years on various paradigmatic perspectives from which to conduct qualitative research, their possibilities of combination with epidemiological research, and some implications for the study of health issues are presented.

  11. Creative classroom strategies for teaching nursing research.

    Science.gov (United States)

    Phillips, Regina Miecznikoski

    2014-01-01

    Faculty are constantly challenged to find interesting classroom activities to teach nursing content and engage students in learning. Nursing students and graduates need to use research skills and evidence-based practice as part of their professional care. Finding creative and engaging ways to teach this material in undergraduate nursing programs are essential. This article outlines several successful strategies to engage nursing students in research content in the time and space constraints of the classroom.

  12. Human Induced Pluripotent Stem Cells from Basic Research to Potential Clinical Applications in Cancer

    Directory of Open Access Journals (Sweden)

    Teresa de Souza Fernandez

    2013-01-01

    Full Text Available The human induced pluripotent stem cells (hiPSCs are derived from a direct reprogramming of human somatic cells to a pluripotent stage through ectopic expression of specific transcription factors. These cells have two important properties, which are the self-renewal capacity and the ability to differentiate into any cell type of the human body. So, the discovery of hiPSCs opens new opportunities in biomedical sciences, since these cells may be useful for understanding the mechanisms of diseases in the production of new diseases models, in drug development/drug toxicity tests, gene therapies, and cell replacement therapies. However, the hiPSCs technology has limitations including the potential for the development of genetic and epigenetic abnormalities leading to tumorigenicity. Nowadays, basic research in the hiPSCs field has made progress in the application of new strategies with the aim to enable an efficient production of high-quality of hiPSCs for safety and efficacy, necessary to the future application for clinical practice. In this review, we show the recent advances in hiPSCs’ basic research and some potential clinical applications focusing on cancer. We also present the importance of the use of statistical methods to evaluate the possible validation for the hiPSCs for future therapeutic use toward personalized cell therapies.

  13. AIDS--Challenges to Basic and Clinical Biomedical Research.

    Science.gov (United States)

    Fauci, Anthony S.

    1989-01-01

    Clinical trials and access to therapeutic drugs pose dilemmas for researchers, physicians, and AIDS patients. The National Institute of Allergy and Infectious Diseases, recognizing the need for greater access to drugs by a broader spectrum of the infected population, is establishing the Community Programs for Clinical Research on AIDS. (Author/MLW)

  14. Stem cells: basic research on health, from ethics to panacea

    Directory of Open Access Journals (Sweden)

    Naara Luna

    2007-01-01

    Full Text Available Even though stem cell therapies are still under experimentation, the media has represented them as a panacea that would cure all diseases. This fact secured the authorization for using human embryos as research material. Therapies include manipulation of human material in tissue bioengineering, suggesting a representation of the body as a factory. This article describes stem cell research projects being carried out in the health sciences center of a higher education institution, focusing on field organization and on the system of values underlying scientific activity. Researchers at different levels were interviewed about perspectives on, and implications of, their research in order to analyze the discourse of the projects' participants. Experiments with adult stem cells enjoyed wide support, while the use of human embryos was disputed. The foundations of those arguments were sought in their relation both to the structure of the scientific field and to the researchers' religious background.

  15. Basic research using the 250 KW research reactor triga in Ljubljana, Yugoslavia

    International Nuclear Information System (INIS)

    Dimic, V.

    1983-01-01

    The 25 KW Triga Mark II reactor of J. 'Stefan Institute' was commissioned on May 1966. During the last two years, it has been operated for about 4200 hr/year. According to experience gained with the reactor, most of the cost of reactor operation will be earned through isotope production for local hospitals and industries, performing low cost applied experiments and organizing training courses. The rest was provided through the Research Communities of the Republic of Slovenia. The reactor has been operated for 15 years without major problems and many basic research programmes have been performed. The research is being conducted in the following mainfields: solid state physics, neutron dosimetry, neutron radiography and autoradiography, reactor physics, examination of nuclear fuel using gamma scanning, irradiation of semiconducting materials and neutron activation analysis. (A.J)

  16. Basic Skills Resource Center: Report on the Preliminary Research Findings

    Science.gov (United States)

    1985-01-01

    indicates that the higher the level of processing , the greater the comprehension and recall. This is true of word lists ( Craik & Lockhart , 1972) as well as... Levels of Processing Principle 9 Content-Driven Strategy/Skills Instruction Principle 10 Instruction, Content, and Prior Knowledge Principle 11 Sequencing...34 Ws 1.’t) 0 U) 14 C0 W u w. C -0.0 C) a. I-s U) w~ 0 4) 0 C "q’ 01 .0 0c 414U >4 0.4 F 0 to 0)0 IvJ0 04Cu B-13 Principle 8 ( Levels of Processing ) The

  17. Private Philanthropy and Basic Research in Mid-Twentieth Century America: The Hickrill Chemical Research Foundation.

    Science.gov (United States)

    Gortler, Leon; Weininger, Stephen J

    2017-02-01

    The Hickrill Chemical Research Foundation, located north of New York City on the estate of its patrons, Sylvan and Ruth Alice Norman Weil, had a short (1948-59) but productive life. Ruth Alice Weil received a Ph.D. in organic chemistry in 1947, directed by William von Eggers Doering of Columbia University. She intended that Hickrill contribute to cancer chemotherapy while providing resources for Doering's more speculative research. Ultimately, Doering's commitment to theoretical organic chemistry set Hickrill's research agenda. Lawrence Knox, an African American with a Harvard Ph.D., supervised the laboratory's daily activities. Hickrill's two dozen postdoctoral fellows produced path-breaking results in Hückel aromatic theory and reactive intermediate chemistry, fostering the postwar emphasis on "basic science." This essay places the Laboratory's successes in the wider context of postwar politics and scientific priorities. Private philanthropic support of basic science arose because it received little pre-World War II government support. In the immediate postwar period, modest organisations like Hickrill still met a need, but the increasing governmental defence- and non-defence-related support for science eventually rendered them unnecessary.

  18. Can an Understanding of Basic Research Facilitate the Effectiveness of Practitioners? Reflections and Personal Perspectives

    Science.gov (United States)

    Sidman, Murray

    2011-01-01

    I have written before about the importance of applied behavior analysis to basic researchers. That relationship is, however, reciprocal; it is also critical for practitioners to understand and even to participate in basic research. Although applied problems are rarely the same as those investigated in the laboratory, practitioners who understand…

  19. Melodic Intonation Therapy: Back to Basics for Future Research

    Directory of Open Access Journals (Sweden)

    Anna eZumbansen

    2014-01-01

    Full Text Available We present a critical review of the literature on Melodic intonation therapy (MIT, one of the most formalized treatments used by speech-language therapist in Broca’s aphasia. We suggest basic clarifications to enhance the scientific support of this promising treatment. First, MIT is a program, not a single speech facilitation technique. The goal of MIT is to restore propositional speech. The rational is that patients can learn a new way to speak through singing by using language-capable regions of the right cerebral hemisphere. We argue that many treatment programs covered in systematic reviews on MIT’s efficacy do not match MIT’s therapeutic goal and rationale. Second, we distinguish between the immediate effect of MIT’s main speech facilitation technique (i.e., intoned-speech and the effect of the entire program on language recovery. Many results in the MIT literature can be explained by this duration factor. Finally, we propose that MIT can be viewed as a treatment of apraxia of speech more than aphasia. This issue should be explored in future experimental studies.

  20. On recent progress using QCLs for molecular trace gas detection - from basic research to industrial applicaitons

    NARCIS (Netherlands)

    Röpcke, J.; Davies, P.; Hempel, F.; Hübner, M.; Glitsch, S.; Lang, N.; Nägele, M.; Rousseau, A.; Wege, S.; Welzel, S.

    2010-01-01

    Quantum Cascade Lasers offer attractive options for applications of MIR absorption spectroscopy for basic research and industrial process control. The contribution reviews applications for plasma diagnostics and trace gas monitoring in research and industry.

  1. Designing Production Based Learning as a Basic Strategy for Creating Income Generating Units at Universitas Pendidikan Indonesia

    Science.gov (United States)

    Suryadi, D.; Supriatna, N.

    2018-02-01

    The establishment of Universitas Pendidikan Indonesia (later to be referred as UPI) Statute as a State-Owned State University (PTN-BH) has implications for UPI requirements. One of them is the need for UPI to generate an Income Generating Unit (IGU) of at least IDR 100 Billion (one hundred billion rupiah). This requirement is considered difficult since UPI is one of the universities whose focus is on the world of education and not the business and industry. Surely this becomes the thinking of the entire academic community to make a breakthrough by optimizing their potential. This study aims to find the pattern of learning practice that produces economic value products as one indicator of IGU value achievement as an effort to support UPI as PTN-BH. Learning strategy is done by designing and implementing the production base learning (PBL) approach as the basis strategy for the development of production units capable of becoming IGU in UPI. The research method used refers to research and development methods with adjustments taking into account the effectiveness in validating and conducting field model trials. The result of this research is the basic design of PBL model as the development strategy of production unit in the achievement of IGU UPI PTN-BH.

  2. Artificial Sight Basic Research, Biomedical Engineering, and Clinical Advances

    CERN Document Server

    Humayun, Mark S; Chader, Gerald; Greenbaum, Elias

    2008-01-01

    Artificial sight is a frontier area of modern ophthalmology combining the multidisciplinary skills of surgical ophthalmology, biomedical engineering, biological physics, and psychophysical testing. Many scientific, engineering, and surgical challenges must be surmounted before widespread practical applications can be realized. The goal of Artificial Sight is to summarize the state-of-the-art research in this exciting area, and to describe some of the current approaches and initiatives that may help patients in a clinical setting. The Editors are active researchers in the fields of artificial sight, biomedical engineering and biological physics. They have received numerous professional awards and recognition for their work. The artificial sight team at the Doheny Eye Institute, led by Dr. Mark Humayun, is a world leader in this area of biomedical engineering and clinical research. Key Features Introduces and assesses the state of the art for a broad audience of biomedical engineers, biophysicists, and clinical...

  3. Basic research needs and opportunities on interfaces in solar materials

    Energy Technology Data Exchange (ETDEWEB)

    Czanderna, A. W.; Gottschall, R. J. [eds.

    1981-04-01

    The workshop on research needs and recommended research programs on interfaces in solar energy conversion devices was held June 30-July 3, 1980. The papers deal mainly with solid-solid, solid-liquid, and solid-gas interfaces, sometimes involving multilayer solid-solid interfaces. They deal mainly with instrumental techniques of studying these interfaces so they can be optimized, so they can be fabricated with quality control and so changes with time can be forecast. The latter is required because a long lifetime (20 yrs is suggested) is necessary for economic reasons. Fifteen papers have been entered individually into EDB and ERA. (LTN)

  4. Radiolabeling Silica-Based Nanoparticles via Coordination Chemistry: Basic Principles, Strategies, and Applications.

    Science.gov (United States)

    Ni, Dalong; Jiang, Dawei; Ehlerding, Emily B; Huang, Peng; Cai, Weibo

    2018-03-20

    As one of the most biocompatible and well-tolerated inorganic nanomaterials, silica-based nanoparticles (SiNPs) have received extensive attention over the last several decades. Recently, positron emission tomography (PET) imaging of radiolabeled SiNPs has provided a highly sensitive, noninvasive, and quantitative readout of the organ/tissue distribution, pharmacokinetics, and tumor targeting efficiency in vivo, which can greatly expedite the clinical translation of these promising NPs. Encouraged by the successful PET imaging of patients with metastatic melanoma using 124 I-labeled ultrasmall SiNPs (known as Cornell dots or C dots) and their approval as an Investigational New Drug (IND) by the United States Food and Drug Administration, different radioisotopes ( 64 Cu, 89 Zr, 18 F, 68 Ga, 124 I, etc.) have been reported to radiolabel a wide variety of SiNPs-based nanostructures, including dense silica (dSiO 2 ), mesoporous silica (MSN), biodegradable mesoporous silica (bMSN), and hollow mesoporous silica nanoparticles (HMSN). With in-depth knowledge of coordination chemistry, abundant silanol groups (-Si-O-) on the silica surface or inside mesoporous channels not only can be directly used for chelator-free radiolabeling but also can be readily modified with the right chelators for chelator-based labeling. However, integrating these labeling strategies for constructing stably radiolabeled SiNPs with high efficiency has proven difficult because of the complexity of the involved key parameters, such as the choice of radioisotopes and chelators, nanostructures, and radiolabeling strategy. In this Account, we present an overview of recent progress in the development of radiolabeled SiNPs for cancer theranostics in the hope of speeding up their biomedical applications and potential translation into the clinic. We first introduce the basic principles and mechanisms for radiolabeling SiNPs via coordination chemistry, including general rules of selecting proper

  5. Using Calibrated Peer Review to Teach Basic Research Skills

    Science.gov (United States)

    Bracke, Marianne S.; Graveel, John G.

    2014-01-01

    Calibrated Peer Review (CPR) is an online tool being used in the class Introduction to Agriculture and Purdue University (AGR 10100) to integrate a writing and research component (http://cpr.molsci.ucla.edu/Home.aspx). Calibrated Peer Review combines the ability to create writing intensive assignments with an introduction to the peer-review…

  6. Teaching Medical Students Basic Neurotransmitter Pharmacology Using Primary Research Resources

    Science.gov (United States)

    Halliday, Amy C.; Devonshire, Ian M.; Greenfield, Susan A.; Dommett, Eleanor J.

    2010-01-01

    Teaching pharmacology to medical students has long been seen as a challenge, and one to which a number of innovative approaches have been taken. In this article, we describe and evaluate the use of primary research articles in teaching second-year medical students both in terms of the information learned and the use of the papers themselves. We…

  7. Basic to industrial research on neutron platform in Japan

    Indian Academy of Sciences (India)

    Building on these successes, a new spallation neutron source (KENS) was con- structed at KEK (the present High Energy Accelerator Research Organization) in. 618. Pramana – J. Phys., Vol. 71, No. ... Ministry of Education, Science and Culture (MONBUSHO) planned the Hadron. Project consisting of four major facilities ...

  8. The application of 10CFR830. 120 in a basic research environment

    Energy Technology Data Exchange (ETDEWEB)

    Bodnarczuk, M.

    1991-04-01

    In this paper, I describe the process of applying the 10 basic criteria of the proposed 10CFR830.120 to a basic research environment like Fermilab and discuss some of the issues associated with the implementation of such a program. I will also discuss some of the differences and similarities between the 18 basic elements of NQA-1 and the 10 criteria of 10CFR830.120 along with the more philosophical'' issues associated with performance versus process- based approach to quality in basic research.

  9. Extramural Research Grants and Scientists’ Funding Strategies

    DEFF Research Database (Denmark)

    Grimpe, Christoph

    2012-01-01

    Although competitive funding of public research has been characterised as providing output incentives that raise efficiency and productivity, we know very little about whether the quality of a scientist’s research is in fact the primary award criterion on which funding bodies base their grant...... decision. This paper provides insights into scientists’ strategies for obtaining project-based research funding in the presence of multiple funding opportunities. It draws a distinction between four types of grants, including the Sixth Framework Programme for Research and Technological Development (FP6......), government, foundation, and industry grants. Based on a sample of more than 800 scientists at universities and public research institutes in Germany, the results indicate that scientist productivity measured in terms of publication and patent stock is a statistically significant determinant only...

  10. Large Scale Computing and Storage Requirements for Basic Energy Sciences Research

    Energy Technology Data Exchange (ETDEWEB)

    Gerber, Richard; Wasserman, Harvey

    2011-03-31

    The National Energy Research Scientific Computing Center (NERSC) is the leading scientific computing facility supporting research within the Department of Energy's Office of Science. NERSC provides high-performance computing (HPC) resources to approximately 4,000 researchers working on about 400 projects. In addition to hosting large-scale computing facilities, NERSC provides the support and expertise scientists need to effectively and efficiently use HPC systems. In February 2010, NERSC, DOE's Office of Advanced Scientific Computing Research (ASCR) and DOE's Office of Basic Energy Sciences (BES) held a workshop to characterize HPC requirements for BES research through 2013. The workshop was part of NERSC's legacy of anticipating users future needs and deploying the necessary resources to meet these demands. Workshop participants reached a consensus on several key findings, in addition to achieving the workshop's goal of collecting and characterizing computing requirements. The key requirements for scientists conducting research in BES are: (1) Larger allocations of computational resources; (2) Continued support for standard application software packages; (3) Adequate job turnaround time and throughput; and (4) Guidance and support for using future computer architectures. This report expands upon these key points and presents others. Several 'case studies' are included as significant representative samples of the needs of science teams within BES. Research teams scientific goals, computational methods of solution, current and 2013 computing requirements, and special software and support needs are summarized in these case studies. Also included are researchers strategies for computing in the highly parallel, 'multi-core' environment that is expected to dominate HPC architectures over the next few years. NERSC has strategic plans and initiatives already underway that address key workshop findings. This report includes a

  11. Systems Toxicology: From Basic Research to Risk Assessment

    Science.gov (United States)

    2014-01-01

    Systems Toxicology is the integration of classical toxicology with quantitative analysis of large networks of molecular and functional changes occurring across multiple levels of biological organization. Society demands increasingly close scrutiny of the potential health risks associated with exposure to chemicals present in our everyday life, leading to an increasing need for more predictive and accurate risk-assessment approaches. Developing such approaches requires a detailed mechanistic understanding of the ways in which xenobiotic substances perturb biological systems and lead to adverse outcomes. Thus, Systems Toxicology approaches offer modern strategies for gaining such mechanistic knowledge by combining advanced analytical and computational tools. Furthermore, Systems Toxicology is a means for the identification and application of biomarkers for improved safety assessments. In Systems Toxicology, quantitative systems-wide molecular changes in the context of an exposure are measured, and a causal chain of molecular events linking exposures with adverse outcomes (i.e., functional and apical end points) is deciphered. Mathematical models are then built to describe these processes in a quantitative manner. The integrated data analysis leads to the identification of how biological networks are perturbed by the exposure and enables the development of predictive mathematical models of toxicological processes. This perspective integrates current knowledge regarding bioanalytical approaches, computational analysis, and the potential for improved risk assessment. PMID:24446777

  12. ARI Basic Research Program FY 1999-2000

    Science.gov (United States)

    1999-06-01

    making self-assessments. The groups are balanced with respect to the number of males and females respectively. Learning and retention are measured by the...remain unchanged? PROGRESS Two sets of findings have emerged from our research: (1) the impact of war mobilization on men’s worklife , and (2) on men’s...mobilization effects on men’s worklife immediately after the war, in pulling men out of productive careers, and in generating worklife discontinuity. By

  13. Basic Research Opportunities in Cu-Chalcopyrite Photovoltaics: Preprint

    International Nuclear Information System (INIS)

    Rockett, A.; Bhattacharya, R. N.; Kapur, V.; Wei, S. H.

    1999-01-01

    A brief review is presented of fundamental research topics of primary importance to the development of improved solar cells based on chalcopyrite-structure materials. The opinions presented are a consensus opinion of the authors of the paper, with input from members of the chalcopyrite solar cells research community in the United States. Major topical areas identified included, in order of importance, are (1) development of an integrated predictive understanding of CIGS(S) materials and devices, (2) development of novel deposition techniques and characterization of the mechanisms of growth in existing and novel processes, (3) novel materials, especially with wide-energy gaps (is greater than or equal to 1.7 eV) other than Cu-based chalcopyrites, (4) development of real-time material characterizations for process control, and (5) alternative front- and rear-contact materials. Although the five topics identified are quite broad, they do not include all topics of interest. Also discussed briefly are some other potential research areas not in the highest priority topics, in particular, areas identified as primarily ''engineering'' rather than ''science.''

  14. Optimal Pricing Strategy in Marketing Research Consulting.

    OpenAIRE

    Chang, Chun-Hao; Lee, Chi-Wen Jevons

    1994-01-01

    This paper studies the optimal pricing scheme for a monopolistic marketing research consultant who sells high-cost proprietary marketing information to her oligopolistic clients in the manufacturing industry. In designing an optimal pricing strategy, the consultant needs to fully consider the behavior of her clients, the behavior of the existing and potential competitors to her clients, and the behavior of her clients' customers. The authors show how the environment uncertainty, the capabilit...

  15. MPD thruster research issues, activities, strategies

    Science.gov (United States)

    1991-01-01

    The following activities and plans in the MPD thruster development are summarized: (1) experimental and theoretical research (magnetic nozzles at present and high power levels, MPD thrusters with applied fields extending into the thrust chamber, and improved electrode performance); and (2) tools (MACH2 code for MPD and nozzle flow calculation, laser diagnostics and spectroscopy for non-intrusive measurements of flow conditions, and extension to higher power). National strategies are also outlined.

  16. Comparative analysis as a basic research orientation: Key methodological problems

    Directory of Open Access Journals (Sweden)

    N P Narbut

    2015-12-01

    Full Text Available To date, the Sociological Laboratory of the Peoples’ Friendship University of Russia has accumulated a vast experience in the field of cross-cultural studies reflected in the publications based on the results of mass surveys conducted in Moscow, Maikop, Beijing, Guangzhou, Prague, Belgrade, and Pristina. However, these publications mainly focus on the comparisons of the empirical data rather than methodological and technical issues, that is why the aim of this article is to identify key problems of the comparative analysis in cross-cultural studies that become evident only if you conduct an empirical research yourself - from the first step of setting the problem and approving it by all the sides (countries involved to the last step of interpreting and comparing the data obtained. The authors are sure that no sociologist would ever doubt the necessity and importance of comparative analysis in the broadest sense of the word, but at the same time very few are ready to discuss its key methodological challenges and prefer to ignore them completely. We summarize problems of the comparative analysis in sociology as follows: (1 applying research techniques to the sample in another country - both in translating and adapting them to different social realities and worldview (in particular, the problematic status of standardization and qualitative approach; (2 choosing “right” respondents to question and relevant cases (cultures to study; (3 designing the research scheme, i.e. justifying the sequence of steps (what should go first - methodology or techniques; (4 accepting the procedures that are correct within one country for cross-cultural work (whether or not that is an appropriate choice.

  17. Basic science research and education: a priority for training and capacity building in developing countries.

    Science.gov (United States)

    Deckelbaum, Richard J; Ntambi, James M; Wolgemuth, Debra J

    2011-09-01

    This article provides evidence that basic science research and education should be key priorities for global health training, capacity building, and practice. Currently, there are tremendous gaps between strong science education and research in developed countries (the North) as compared to developing countries (the South). In addition, science research and education appear as low priorities in many developing countries. The need to stress basic science research beyond the typical investment of infectious disease basic service and research laboratories in developing areas is significant in terms of the benefits, not only to education, but also for economic strengthening and development of human resources. There are some indications that appreciation of basic science research education and training is increasing, but this still needs to be applied more rigorously and strengthened systematically in developing countries. Copyright © 2011 Elsevier Inc. All rights reserved.

  18. Basics of case report form designing in clinical research

    Directory of Open Access Journals (Sweden)

    Shantala Bellary

    2014-01-01

    Full Text Available Case report form (CRF is a specialized document in clinical research. It should be study protocol driven, robust in content and have material to collect the study specific data. Though paper CRFs are still used largely, use of electronic CRFs (eCRFS are gaining popularity due to the advantages they offer such as improved data quality, online discrepancy management and faster database lock etc. Main objectives behind CRF development are preserving and maintaining quality and integrity of data. CRF design should be standardized to address the needs of all users such as investigator, site coordinator, study monitor, data entry personnel, medical coder and statistician. Data should be organized in a format that facilitates and simplifies data analysis. Collection of large amount of data will result in wasted resources in collecting and processing it and in many circumstances, will not be utilized for analysis. Apart from that, standard guidelines should be followed while designing the CRF. CRF completion manual should be provided to the site personnel to promote accurate data entry by them. These measures will result in reduced query generations and improved data integrity. It is recommended to establish and maintain a library of templates of standard CRF modules as they are time saving and cost-effective. This article is an attempt to describe the methods of CRF designing in clinical research and discusses the challenges encountered in this process.

  19. Basics of case report form designing in clinical research.

    Science.gov (United States)

    Bellary, Shantala; Krishnankutty, Binny; Latha, M S

    2014-10-01

    Case report form (CRF) is a specialized document in clinical research. It should be study protocol driven, robust in content and have material to collect the study specific data. Though paper CRFs are still used largely, use of electronic CRFs (eCRFS) are gaining popularity due to the advantages they offer such as improved data quality, online discrepancy management and faster database lock etc. Main objectives behind CRF development are preserving and maintaining quality and integrity of data. CRF design should be standardized to address the needs of all users such as investigator, site coordinator, study monitor, data entry personnel, medical coder and statistician. Data should be organized in a format that facilitates and simplifies data analysis. Collection of large amount of data will result in wasted resources in collecting and processing it and in many circumstances, will not be utilized for analysis. Apart from that, standard guidelines should be followed while designing the CRF. CRF completion manual should be provided to the site personnel to promote accurate data entry by them. These measures will result in reduced query generations and improved data integrity. It is recommended to establish and maintain a library of templates of standard CRF modules as they are time saving and cost-effective. This article is an attempt to describe the methods of CRF designing in clinical research and discusses the challenges encountered in this process.

  20. Artificial Intelligence Needs More Emphasis on Basic Research: President's Quarterly Message

    OpenAIRE

    McCarthy, John

    1983-01-01

    Too few people are doing basic research in AI relative to the number working on applications. The ratio of basic/applied is less in AI than in the older sciences and than in computer science generally. This is unfortunate, because reaching human level artificial intelligence will require fundamental conceptual advances.

  1. Basic research in PCOS: are we reaching new frontiers?

    Science.gov (United States)

    Ben-Shlomo, Izhar; Younis, Johnny S

    2014-06-01

    Polycystic ovarian syndrome (PCOS) is the leading cause for anovulatory infertility. It is diagnosed by two of the following three clinical criteria: oligomenorrhoea, hyperandrogenism and polycystic appearance of the ovaries. Weight loss and physical activity can lead to ovulation and conception. Lowering of serum insulin normalizes androgen concentrations whereas ovulation induction often causes ovarian hyperstimulation. Theca cells from PCOS ovaries may be more responsive to insulin than cells from non-PCOS ovaries. Herein we review the research efforts at the genomic and cell function levels, as well as animal models, which have been made to elucidate the underlying mechanism that leads to PCOS. It appears that, despite the impressive amount of data that have been generated in these studies, the mechanism of this syndrome is still only partially understood. Polycystic ovarian syndrome (PCOS) is the leading cause for infertility, which is caused by anovulation. It is diagnosed by two of the following three clinical criteria: irregular and prolonged menstrual cycles, overt symptoms of excess androgens, which is revealed by acne and excess hair, and ultrasonographic appearance of the ovaries with multiple small follicles spread mainly near the ovarian surface, which gave it its name. Intentional weight loss and physical activity can lead to resumption of ovulation and not infrequently to conception as well. It was shown that lowering of serum insulin accounts for normalization of serum androgen levels, whereas ovulation induction with FSH often causes ovarian hyperstimulation. It is suggested that theca cells from PCOS ovaries may be more responsive to insulin than cells from non-PCOS ovaries. In this article we review the efforts to define the genes responsible for the syndrome and the studies at the cell function level, as well as animal models, which have been done to elucidate the underlying mechanism that leads to PCOS. Overall, it appears that despite the

  2. Basic research needs to assure a secure energy future. A report from the Basic Energy Sciences Advisory Committee

    Energy Technology Data Exchange (ETDEWEB)

    None

    2003-02-01

    This report has highlighted many of the possible fundamental research areas that will help our country avoid a future energy crisis. The report may not have adequately captured the atmosphere of concern that permeated the discussions at the workshop. The difficulties facing our nation and the world in meeting our energy needs over the next several decades are very challenging. It was generally felt that traditional solutions and approaches will not solve the total energy problem. Knowledge that does not exist must be obtained to address both the quantity of energy needed to increase the standard of living world-wide and the quality of energy generation needed to preserve the environment. In terms of investments, it was clear that there is no single research area that will secure the future energy supply. A diverse range of economic energy sources will be required--and a broad range of fundamental research is needed to enable these. Many of the issues fall into the traditional materials and chemical sciences research areas, but with specific emphasis on understanding mechanisms, energy related phenomena, and pursuing novel directions in, for example, nanoscience and integrated modeling. An important result from the discussions, which is hopefully apparent from the brief presentations above, is that the problems that must be dealt with are truly multidisciplinary. This means that they require the participation of investigators with different skill sets. Basic science skills have to be complemented by awareness of the overall nature of the problem in a national and world context, and with knowledge of the engineering, design, and control issues in any eventual solution. It is necessary to find ways in which this can be done while still preserving the ability to do first-class basic science. The traditional structure of research, with specific disciplinary groupings, will not be sufficient. This presents great challenges and opportunities for the funders of the

  3. Annual progress report of the physical chemistry department. Basic research 1987

    International Nuclear Information System (INIS)

    1988-01-01

    Basic research for 1987 in physical chemistry of the French Atomic Energy Commission are reviewed. Topics include molecular chemistry, isotopic geochemistry, molecular photophysics, laser photochemistry, solid and surface physical chemistry. A list of publications and thesis is given [fr

  4. Basic Research Needs for Clean and Efficient Combustion of 21st Century Transportation Fuels

    Energy Technology Data Exchange (ETDEWEB)

    McIlroy, A.; McRae, G.; Sick, V.; Siebers, D. L.; Westbrook, C. K.; Smith, P. J.; Taatjes, C.; Trouve, A.; Wagner, A. F.; Rohlfing, E.; Manley, D.; Tully, F.; Hilderbrandt, R.; Green, W.; Marceau, D.; O' Neal, J.; Lyday, M.; Cebulski, F.; Garcia, T. R.; Strong, D.

    2006-11-01

    To identify basic research needs and opportunities underlying utilization of evolving transportation fuels, with a focus on new or emerging science challenges that have the potential for significant long-term impact on fuel efficiency and emissions.

  5. Recruitment Issues and Strategies for Adults Who Are Not Currently Participating in Literacy and Adult Basic Education (ABE) Programs.

    Science.gov (United States)

    Kohring, Aaron

    Adult basic education (ABE) and literacy programs have used many different strategies and tools to recruit new students. A small sampling of Tennessee ABE programs shows the more effective recruitment strategies are word-of-mouth referrals; newspaper advertisements and articles; fliers; brochures; posters, radio messages, and public service…

  6. Basic research using the 250 kW research reactor of the Jozef Stefan Institute

    International Nuclear Information System (INIS)

    Dimic, V.

    1984-01-01

    The 250 kW TRIGA Mark II reactor is a light water reactor with solid fuel elements in which the zirconium hydride moderator is homogeneously distributed between enriched uranium. The reactor therefore has a large prompt negative temperature coefficient of reactivity; the fuel also has a very high retention of radioactive fission products. The experimental facilities include a rotary specimen rack, a central in-core radiation thimble, a pneumatic transfer system and pulsing capability. Other experimental facilities include two radial and two tangential beam tubes, a graphite thermal column and a graphite thermalizing column. At the steady state power of 250 kW the peak flux is 1x10 13 n/cm 2 in the central test position. In addition, pulsing to about 2000 MW is usually provided giving peak fluxes of about 2x10 16 n/cm 2 sec. All TRIGA reactors produce a core-average thermal neutron flux of about 10 7 n.v. per watt. Only with very large accelerators can such high fluxes be achieved. The types of research could be summarized as follows: thermal neutron scattering, neutron radiography, neutron and nuclear physics, activation analysis, radiochemistry, biology and medicine, and teaching and training. Typical applied research with a 250 kW reactor has been conducted in medicine, in biology, archaeology, metallurgy and materials science, engineering and criminology. It is well known that research reactors have been used routinely to produce isotopes for industry and medicine. We can conclude that the 250 kW TRIGA reactor is a useful and wide ranging source of radiation for basic and applied research. The operation cost for this instrument is relatively low. (author)

  7. Fiscal 1999 research report on long-term energy technology strategy. Basic research on industrial technology strategy (Individual technology strategy). Human life, medical care and welfare field (Medical health care technology field); 1999 nendo choki energy gijujtsu senryaku ni kansuru chosa hokokusho. Sangyo gijutsu senryaku sakutei kiban chosa (bun'yabetsu gijutsu senryaku) ningen seikatsu iryo fukushi bun'ya (medidal health care gijutsu bun'ya)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This report summarizes the fiscal 1999 research result on Japanese technology competitiveness, future trend, technology innovation and policy needs in a medical health care field. Future international growth of a medical health care equipment industry is promising because of an expected progress of medical care technology, change in medical care needs and creation of the new global market. The current highlighted technical trend is fusion of medical technology with network, system, biotechnology and micro-machine technologies, and such fusion is expected to contribute to daily use, less/no invasion and improvement of medical treatment. Industry-government cooperative measures for upgrading an international competitiveness are as follows: an approach as national policy by preparing Japanese BECOM, preparation of a system supporting venture businesses for developing medical health care equipment, and systematic establishment of a medical-engineering cooperative system. Preparation of a complementary relation with overseas countries is also desirable. (NEDO)

  8. Investigation research of core-basic information associated with the coupling analysis. Outline report

    International Nuclear Information System (INIS)

    Kataoka, Shinichi; Matsunaga, Kenichi; Ishihara, Yoshinao; Kawahara, Kenichi; Neyama, Atsushi; Nakagawa, Koichi; Iwata, Hiroshi; Mori, Koji

    2001-03-01

    The newest literature information in the foreign countries was researched, and this research showed the basic concept of the coupling analysis code to realize coupling analysis in near field of the geological disposal system. The outline of this research is shown in the following. (1) The combination of M (Mechanical) and C (Chemistry) is placed on the weak relations, because coupling analysis of the United States Yucca Mountain limits a site and the specifications of engineered barrier. (2) One of the purposes of this research is information collecting about coupling analysis code NUFT-C adopted in the United States Yucca Mountain. Therefore, we carried out an information exchange with the United States Lawrence Livermore National Laboratory. We could collect the development purpose of analysis code, key function, and information such as a test case analysis. (3) The investigation of the analysis code concerned with the newest information of coupling analysis which contains the geochemistry process and 2 phase system was done based on the public information for the purpose of building some concept of the coupling analysis code, the extraction of the development issues. It could be understood about the future development strategy and the precaution in addition to a phenomenon to deal with, the current status of the coupling analysis technique as a result of the investigation. (4) It was cleared about the mission of the coupling analysis code and the requirement items (function, quality) by this research. Then, some development options were presented. (5) It was studied about the procedure of developing it to satisfy the above requirement toward the conditions that a site isn't selected, the short development. The tool (Diffpack) which could cope with the speed-up of the calculation time and visualization flexibly was effective, and it was summarized about the test case by using this tool, the key function of this tool as that result. (author)

  9. Cannabinoids and Vanilloids in Schizophrenia: Neurophysiological Evidence and Directions for Basic Research

    Directory of Open Access Journals (Sweden)

    Rafael N. Ruggiero

    2017-06-01

    Full Text Available Much of our knowledge of the endocannabinoid system in schizophrenia comes from behavioral measures in rodents, like prepulse inhibition of the acoustic startle and open-field locomotion, which are commonly used along with neurochemical approaches or drug challenge designs. Such methods continue to map fundamental mechanisms of sensorimotor gating, hyperlocomotion, social interaction, and underlying monoaminergic, glutamatergic, and GABAergic disturbances. These strategies will require, however, a greater use of neurophysiological tools to better inform clinical research. In this sense, electrophysiology and viral vector-based circuit dissection, like optogenetics, can further elucidate how exogenous cannabinoids worsen (e.g., tetrahydrocannabinol, THC or ameliorate (e.g., cannabidiol, CBD schizophrenia symptoms, like hallucinations, delusions, and cognitive deficits. Also, recent studies point to a complex endocannabinoid-endovanilloid interplay, including the influence of anandamide (endogenous CB1 and TRPV1 agonist on cognitive variables, such as aversive memory extinction. In fact, growing interest has been devoted to TRPV1 receptors as promising therapeutic targets. Here, these issues are reviewed with an emphasis on the neurophysiological evidence. First, we contextualize imaging and electrographic findings in humans. Then, we present a comprehensive review on rodent electrophysiology. Finally, we discuss how basic research will benefit from further combining psychopharmacological and neurophysiological tools.

  10. Energy in Ireland: context, strategy and research

    International Nuclear Information System (INIS)

    Saintherant, N.; Lerouge, Ch.; Welcker, A.

    2008-01-01

    In the present day situation of sudden awareness about climatic change and announced fossil fuels shortage, Ireland has defined a new strategy for its energy future. Context: Ireland is strongly dependent of oil and gas imports which increase regularly to meet the demand. A small part of the electricity consumed is imported from Ulster. The share of renewable energies remains weak but is increasing significantly. Therefore, from 1990 to 2006, the proportion of renewable energies increased from 1.9% (mainly of hydroelectric origin) to 4.5%. Wind power represents now the main renewable energy source. The transportation sector is the most energy consuming and the biggest source of greenhouse gases. Strategy: the Irish policy is driven by pluri-annual strategic plans which define the objectives and means. Priority is given to the security of supplies at affordable prices: 8.5 billion euros will be invested during the 2007-2013 era for the modernization of existing energy infrastructures and companies, and in a lesser extent for the development of renewable energy sources. During this period, 415 million euros more will be devoted to the research, development and demonstration (RD and D) of new energy solutions. Research: in 2005 the energy RD and D expenses reached 12.8 million euros shared between 54% for R and D and 46% for demonstration projects. Half of the financing is given to higher education schools and is devoted to energy saving purposes (33%) and to renewable energies (29%, mainly wind power and biomass). Academic research gives a particular attention to ocean energy which represents an important potential resource in Ireland and which has already led to the creation of innovative companies. The integration of renewable energy sources to the power grid and the stability of supplies are also the object of active researches. (J.S.)

  11. Basic research in crystalline and noncrystalline ceramic systems. Annual report, August 1, 1980-October 31, 1981

    International Nuclear Information System (INIS)

    1981-01-01

    The Basic Research Programs in Ceramics sponsored by the US Department of Energy supports a significant fraction of the research effort and graduate student training in ceramics at MIT. Various research activities involving ceramic materials include electrical properties; kinetic studies; defect structures, defect interactions, grain boundaries and surfaces; sintering studies; and mechanical properties

  12. Pedagogical workshops as a teaching and learning strategy: the hydrographic basic as a theme

    OpenAIRE

    Valéria Brumato Regina Fornazari; Ana Tiyomi Obara

    2017-01-01

    Current research investigates the ideas and practices of a team of teachers of the Natural Sciences working in schools in the state of Paraná, Brazil, with regard to pedagogical workshops as teaching and learning strategies on Hydrographic Basin as theme. A continuous formation course was conducted on the theme, with data retrieved by a questionnaire applied prior to the course and after the development of workshops by the teachers. Films, recordings and descriptive memorials were analyzed ac...

  13. Proceedings of the meeting and scientific presentations on basic science research and nuclear technology

    International Nuclear Information System (INIS)

    Prayitno; Slamet Santosa; Darsono; Syarip; Agus Taftazani; Samin; Tri Mardji Atmono; Dwi Biyantoro; Herry Poernomo; Prajitno; Tjipto Sujitno; Gede Sutresna W; Djoko Slamet Pujorahardjo; Budi Setiawan; Bambang Siswanto; Endro Kismolo; Jumari

    2016-08-01

    The Proceedings of the Meeting and Scientific Presentations on Basic Science Research and Nuclear Technology by Center for Accelerator Science and Technology in Yogyakarta with the theme of Universities and research and development institutions synergy in the development of basic science and nuclear technology held on Surakarta 9 August 2016. This seminar is an annual routine activities of Center for Accelerator Science and Technology for exchange research result among University and BATAN researcher for using nuclear technology. The proceeding consist of 3 article from keynotes’ speaker and 37 articles from BATAN participant as well as outside which have been indexed separately. (MPN)

  14. A roadmap for bridging basic and applied research in forensic entomology.

    Science.gov (United States)

    Tomberlin, J K; Mohr, R; Benbow, M E; Tarone, A M; VanLaerhoven, S

    2011-01-01

    The National Research Council issued a report in 2009 that heavily criticized the forensic sciences. The report made several recommendations that if addressed would allow the forensic sciences to develop a stronger scientific foundation. We suggest a roadmap for decomposition ecology and forensic entomology hinging on a framework built on basic research concepts in ecology, evolution, and genetics. Unifying both basic and applied research fields under a common umbrella of terminology and structure would facilitate communication in the field and the production of scientific results. It would also help to identify novel research areas leading to a better understanding of principal underpinnings governing ecosystem structure, function, and evolution while increasing the accuracy of and ability to interpret entomological evidence collected from crime scenes. By following the proposed roadmap, a bridge can be built between basic and applied decomposition ecology research, culminating in science that could withstand the rigors of emerging legal and cultural expectations.

  15. Information-seeking behavior of basic science researchers: implications for library services.

    Science.gov (United States)

    Haines, Laura L; Light, Jeanene; O'Malley, Donna; Delwiche, Frances A

    2010-01-01

    This study examined the information-seeking behaviors of basic science researchers to inform the development of customized library services. A qualitative study using semi-structured interviews was conducted on a sample of basic science researchers employed at a university medical school. The basic science researchers used a variety of information resources ranging from popular Internet search engines to highly technical databases. They generally relied on basic keyword searching, using the simplest interface of a database or search engine. They were highly collegial, interacting primarily with coworkers in their laboratories and colleagues employed at other institutions. They made little use of traditional library services and instead performed many traditional library functions internally. Although the basic science researchers expressed a positive attitude toward the library, they did not view its resources or services as integral to their work. To maximize their use by researchers, library resources must be accessible via departmental websites. Use of library services may be increased by cultivating relationships with key departmental administrative personnel. Despite their self-sufficiency, subjects expressed a desire for centralized information about ongoing research on campus and shared resources, suggesting a role for the library in creating and managing an institutional repository.

  16. [Factors influencing research activity of Andalusian nurses and improvement strategies].

    Science.gov (United States)

    López Alonso, Sergio R; Gálvez González, María; Amezcua, Manuel

    2013-04-01

    To identify factors influencing research activity of Andalusian nurses and to find improvement strategies. Qualitative research using SWOT analysis (weaknesses, threats, strengths, opportunities). Nurses were selected deliberately in eight groups according to predetermined criteria. Analysis included categorization and relationship of factors and strategies. 81 participants were included in groups of 7-12 range. 45 categories were identified with 212 factors: 12 weaknesses (50 factors), 10 strengths (44 factors), 12 threats (68 factors) and 11 opportunities (50 factors). In addition, 32 categories were identified with 53 strategies: 14 categories of W-T strategies (42 strategies), 3 categories of S-T strategies (11 strategies), 5 categories of W-O strategies (13 strategies) and 10 categories of S-O strategies (41 strategies). Nurses identified numerous factors, mainly threats. The strategies are focused on W-T but they also suggest many but weak 5-0 strategies due to the low potential of the opportunities and strengths perceived.

  17. A ProCoS II Project Final Report: ESPRIT Basic Research project 707

    DEFF Research Database (Denmark)

    Bowen, J. P.; Hoare, C. A. R.; Langmaack, Hans

    1996-01-01

    An overview of the research and associated activities of the Europeancollaborative ESPRIT Basic Research ProCoS II project (no. 7071) on``Provably Correct Systems'' which ran from 1992 to 1995 is presented.This was a follow-on project to ProCoS (no. 3104) and ran inparallel with the ProCoS Working...

  18. Possibilities of basic and applied researches using low energy ion beams accelerators

    International Nuclear Information System (INIS)

    Morales, Roberto

    1996-01-01

    Full text: The availability of ion sources that allow to accelerate heavy and light ions, and the new compact accelerators have opened interesting possibilities for using in basic and applied research, Some of the research lines such as material, environmental, archaeology, bio-medicine are shown

  19. Key trends in basic and application-oriented research on nanomaterials

    Energy Technology Data Exchange (ETDEWEB)

    Tretyakov, Yuri D; Goodilin, Eugene A [Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow (Russian Federation)

    2009-09-30

    Key trends in basic and application-oriented research on nanomaterials are considered. It is noted that some studies are now carried out abroad and in domestic laboratories, while some other are to be initiated in the near future. It is emphasized that effective research in the field in question is possible only provided that laboratories are equipped with advanced instrumentation.

  20. Key trends in basic and application-oriented research on nanomaterials

    International Nuclear Information System (INIS)

    Tretyakov, Yuri D; Goodilin, Eugene A

    2009-01-01

    Key trends in basic and application-oriented research on nanomaterials are considered. It is noted that some studies are now carried out abroad and in domestic laboratories, while some other are to be initiated in the near future. It is emphasized that effective research in the field in question is possible only provided that laboratories are equipped with advanced instrumentation.

  1. Refueling strategy at the Budapest research reactor

    International Nuclear Information System (INIS)

    Hargitai, Timor

    1998-01-01

    Refueling strategy is very important for nuclear power plants and for highly utilized research reactors with power level in the megawatt range. New core design shall fulfill several demands and needs which can contradict each other sometimes. The loaded uranium quantity should assure the scheduled operation time (energy generation) and the maneuvering capability even at the end of the campaign. On the other hand the built in excess reactivity cannot be too high, because otherwise it would jeopardize the shutdown margin and reactor safety. Moreover the core arrangement should be optimum for in-core irradiation purposes and for the beam port experiments too. Sometimes this demand can be in contradiction with the desired burnup level. The achieved burnup level is very important from the fresh fuel consumption point of view, which has direct economic significance, however the generated spent fuel quantity is an important issue too. The refueling technique presented here allowed us at the Budapest Research Reactor to reach average burnup levels superseding 60%. (author)

  2. The Basic Challenge in EU Countries Promotion Strategy in Exporting Commercial Services

    Directory of Open Access Journals (Sweden)

    Octavian-Liviu Olaru

    2012-05-01

    Full Text Available The global financial and economic crisis which started in 2007 had a considerable impact onthe international exchange of goods and services and on the intensity of global financial flows andbusiness activity. Starting with 2010, the EU-27 economy returned to its previous trend of progressivelymore integration with the international economy in terms of its level of credits and debits relative togross domestic product (GDP, having experienced a reversal in 2009. The average value of EU-27 tradeflows of goods corresponded to 11.6 % of GDP in 2010, up from 9.8 % the previous year. The level oftrade integration of services rose to 4.0 % of GDP in 2010, up from 3.9 % in 2008 and 3.8 % in 2009.The basic challenge in EU countries promotion strategy in exporting a commercial service is to convincea foreigner to try a service that does not exist yet. The foreigners have to believe that the service will beof good quality and will meet their needs. Usually the foreigner forms that belief based onrecommendations, referrals, or somehow seeing the service provider in action. There are also severalroles that trade promotion activities can play in building that belief or credibility. A national TPO needsto find or reinforce some special quality that its country has so that when potential customers hear abouta service supplier from this country, their first response is, “Oh yes, I’ve heard good things aboutservices from your country.”

  3. Discovery of the "RNA continent" through a contrarian's research strategy.

    Science.gov (United States)

    Hayashizaki, Yoshihide

    2011-01-01

    The International Human Genome Sequencing Consortium completed the decoding of the human genome sequence in 2003. Readers will be aware of the paradigm shift which has occurred since then in the field of life science research. At last, mankind has been able to focus on a complete picture of the full extent of the genome, on which is recorded the basic information that controls all life. Meanwhile, another genome project, centered on Japan and known as the mouse genome encyclopedia project, was progressing with participation from around the world. Led by our research group at RIKEN, it was a full-length cDNA project which aimed to decode the whole RNA (transcriptome) using the mouse as a model. The basic information that controls all life is recorded on the genome, but in order to obtain a complete picture of this extensive information, the decoding of the genome alone is far from sufficient. These two genome projects established that the number of letters in the genome, which is the blueprint of life, is finite, that the number of RNA molecules derived from it is also finite, and that the number of protein molecules derived from the RNA is probably finite too. A massive number of combinations is still involved, but we are now able to understand one section of the network formed by these data. Once an object of study has been understood to be finite, establishing an image of the whole is certain to lead us to an understanding of the whole. Omics is an approach that views the information controlling life as finite and seeks to assemble and analyze it as a whole. Here, I would like to present our transcriptome research while making reference to our unique research strategy.

  4. Clinical Research Strategies for Fructose Metabolism12

    Science.gov (United States)

    Laughlin, Maren R.; Bantle, John P.; Havel, Peter J.; Parks, Elizabeth; Klurfeld, David M.; Teff, Karen; Maruvada, Padma

    2014-01-01

    Fructose and simple sugars are a substantial part of the western diet, and their influence on human health remains controversial. Clinical studies in fructose nutrition have proven very difficult to conduct and interpret. NIH and USDA sponsored a workshop on 13–14 November 2012, “Research Strategies for Fructose Metabolism,” to identify important scientific questions and parameters to be considered while designing clinical studies. Research is needed to ascertain whether there is an obesogenic role for fructose-containing sugars via effects on eating behavior and energy balance and whether there is a dose threshold beyond which these sugars promote progression toward diabetes and liver and cardiovascular disease, especially in susceptible populations. Studies tend to fall into 2 categories, and design criteria for each are described. Mechanistic studies are meant to validate observations made in animals or to elucidate the pathways of fructose metabolism in humans. These highly controlled studies often compare the pure monosaccharides glucose and fructose. Other studies are focused on clinically significant disease outcomes or health behaviors attributable to amounts of fructose-containing sugars typically found in the American diet. These are designed to test hypotheses generated from short-term mechanistic or epidemiologic studies and provide data for health policy. Discussion brought out the opinion that, although many mechanistic questions concerning the metabolism of monosaccharide sugars in humans remain to be addressed experimentally in small highly controlled studies, health outcomes research meant to inform health policy should use large, long-term studies using combinations of sugars found in the typical American diet rather than pure fructose or glucose. PMID:24829471

  5. Industry's demand for the BESSY synchrotron radiation (SR): approaches towards interlinking basic scientific research activities and industry

    International Nuclear Information System (INIS)

    Bierhals, R.; Schmoch, U.; Nick, D.; Pilorget, L.; Ritschel, C.; Walter, G.H.

    1994-08-01

    In Germany, industry's demand for synchrotron radiation (SR) is very limited, due to the current macroeconomic situation and the corporate strategy of potential SR users in industry. This is in contrast to the conditions in the USA (and Japan), where industrial enterprises more readily invest in and run their own long-term basic research projects for exploration of potential commercial applications according to their demands, with research goals pursued there and in Germany overlapping to a large extent. It cannot be expected that demand for SR from industry in Germany will ever come up to the level seen in the USA. In Germany, non-university research institutes are most likely to become an important group of potential users of SR. Substantially boosting the demand for SR from industry will need a change of macroeconomic framework conditions affecting the corporate strategy to the effect that industry will more strongly commit itself to and take up responsibility for application-oriented fundamental research and the corresponding technology transfer. This can be achieved by a policy providing both for institutional means and financial incentives. As to near-market, strategic technological developments, establishment of structures allowing direct cooperation of science and technology, for instance in the form of joint ventures, or underwriting agreements and corresponding supervisory boards, seem to be promising. As to basic-research-oriented promotion of research, a technology screening might lead to the selection of technology-relevant research goals, and corresponding financial support from a special fund. Such incentives for cooperative action by technology, science and the government will create novel types of research-industry interfaces in Germany between ''historical'' spheres of autonomy of research of industry and the scientific community. (orig.) [de

  6. Strategies for public health research in European Union countries.

    Science.gov (United States)

    Grimaud, Olivier; McCarthy, Mark; Conceição, Claudia

    2013-11-01

    'Health' is an identifiable theme within the European Union multi-annual research programmes. Public Health Innovation and Research in Europe (PHIRE), led by the European Public Health Association, sought to identify public health research strategies in EU member states. Within PHIRE, national public health associations reviewed structures for health research, held stakeholder workshops and produced reports. This information, supplemented by further web searches, including using assisted translation, was analysed for national research strategies and health research strategies. All countries described general research strategies, outlining organizational and capacity objectives. Thematic fields, including health, are mentioned in some strategies. A health research strategy was identified for 15 EU countries and not for 12. Ministries of health led research strategies for nine countries. Public health research was identified in only three strategies. National research strategies did not refer to the European Union's health research programme. Public health research strategies of European countries need to be developed by ministries of health, working with the research community to achieve the European Research Area.

  7. Basic research on nonlinear instability phenomena of liquid surface. Fiscal year 1996 report on preceding basic engineering field

    International Nuclear Information System (INIS)

    Madarame, Haruki; Okamoto, Koji; Iida, Masao

    1997-03-01

    Various nonlinear behaviors caused by nonlinear boundary conditions have been observed, and it is feared that in large vessels like FBRs, the instability phenomena such as self-exciting sloshing may occur in the free liquid surface of coolant. In this research, the nonlinear instability phenomena in free liquid surface were examined by the basic experiment and the analysis. As to the self-exciting oscillation 'jet flutter' of upward plane jet that collides against liquid surface, in order to know the mechanism of determining the frequency and supplying energy, the amplitude and phase relation of various variable quantities were investigated. The simplified model for calculating the displacement of jet was made, and compared with the experiment. The jet flutter phenomena are explained. The interaction of free liquid surface and turbulent flow, which is important for considering the nonlinearity in free liquid surface, was measured by LDV and visualization, and the turbulent flow phenomena in free liquid surface were investigated. In the experiment, turbulent flow energy was given to the free liquid surfaces of water and polymers, and the effect that the Toms effect exerted to interface turbulent flow was observed. The results of these studies are reported. (K.I.) studies are reported. (K.I.)

  8. Programme of basic nuclear research and associated fields 1977-1981

    International Nuclear Information System (INIS)

    1978-01-01

    Nuclear research and development have been intensively pursued in West Germany by the Government and the Laender since 1955. In this period, the aims and official measures for fostering the research and use of nuclear power for peaceful purposes were laid down in four nuclear programmes. The 4th Nuclear Programme covers the period 1973 to 1976. From 1977, nuclear development became part of the energy research programme which was published by the West German Government in the spring of 1977. The basic nuclear research, however, was regarded as part of a total concept for fostering basic research (to be developed). While all the activities of research in the natural sciences and arts fostered by the West German Ministry of Research and Technology were to be co-ordinated in a more schematic form in the plan for 'Basic Research', it is the aim of the present statement to take stock of the present situation in 'Basic Nuclear Research' including the associated fields of 'Nuclear Solid Research' and 'Synchrotron Radiation', to analyse their structure, to describe the scientific aims for the next five years and to determine the total financial requirements. The basis for determining the financial programme worked out by the expert committee on 'Physical Research in the Nuclear Field' and the other committees in this field. The plans are in agreement with the medium term plan of the West German Ministry of Research and Technology (at 27.10.1977) and their contents correspond to the state of affairs at the end of 1977. (orig./UA) [de

  9. Documentation on the interlinked sponsorship programme of the BMFT for basic research in the natural sciences

    International Nuclear Information System (INIS)

    1993-02-01

    The reports from the individual research teams working at various places in Germany show their particular achievements on the one hand, and at the same time illustrate the effectiveness of the interlinked sponsorship concept adopted by the Federal Ministry of Science and Technology (BMFT). There is an annex giving statistical data on the scope and organisation of state sponsorship of basic research bound to large-scale research equipment. (DG) [de

  10. The Impact of "Coat Protein-Mediated Virus Resistance" in Applied Plant Pathology and Basic Research.

    Science.gov (United States)

    Lindbo, John A; Falk, Bryce W

    2017-06-01

    Worldwide, plant viruses cause serious reductions in marketable crop yield and in some cases even plant death. In most cases, the most effective way to control virus diseases is through genetically controlled resistance. However, developing virus-resistant (VR) crops through traditional breeding can take many years, and in some cases is not even possible. Because of this, the demonstration of the first VR transgenic plants in 1985 generated much attention. This seminal report served as an inflection point for research in both basic and applied plant pathology, the results of which have dramatically changed both basic research and in a few cases, commercial crop production. The typical review article on this topic has focused on only basic or only applied research results stemming from this seminal discovery. This can make it difficult for the reader to appreciate the full impact of research on transgenic virus resistance, and the contributions from fundamental research that led to translational applications of this technology. In this review, we take a global view of this topic highlighting the significant changes to both basic and applied plant pathology research and commercial food production that have accumulated in the last 30 plus years. We present these milestones in the historical context of some of the scientific, economic, and environmental drivers for developing specific VR crops. The intent of this review is to provide a single document that adequately records the significant accomplishments of researchers in both basic and applied plant pathology research on this topic and how they relate to each other. We hope this review therefore serves as both an instructional tool for students new to the topic, as well as a source of conversation and discussion for how the technology of engineered virus resistance could be applied in the future.

  11. Migration in Vulnerable Deltas: A Research Strategy

    Science.gov (United States)

    Hutton, C.; Nicholls, R. J.; Allan, A.

    2015-12-01

    C. Hutton1, & R. J. Nicholls1, , 1 University of Southampton, University Road, Southampton, Hampshire, United Kingdom, SO17 1BJ. cwh@geodata. soton.ac.ukAbstractGlobally, deltas contain 500 million people and with rising sea levels often linked to large number of forced migrants are expected in the coming century. However, migration is already a major process in deltas, such as the growth of major cities such as Dhaka and Kolkata. Climate and environmental change interacts with a range of catchment and delta level drivers, which encompass a nexus of sea-level rise, storms, freshwater and sediment supply from the catchment, land degradation, subsidence, agricultural loss and socio-economic stresses. DECCMA (Deltas, Vulnerability and Climate Change: Migration and Adaptation/CARRIA) is investigating migration in the Ganges-Brahmaputra-Meghna (GBM), Mahanadi and Volta Deltas, including the influence of climate change. The research will explore migration from a range of perspectives including governance and stakeholder analysis, demographic analysis, household surveys of sending and receiving areas, macro-economic analysis, and hazards and hotspot analysis both historically and into the future. Migration under climate change will depend on other adaptation in the deltas and this will be examined. Collectively, integrated analysis will be developed to examine migration, other adaptation and development pathways with a particular focus on the implications for the poorest. This will require the development of input scenarios, including expert-derived exogenous scenarios (e.g., climate change) and endogenous scenarios of the delta developed in a participatory manner. This applied research will facilitate decision support methods for the development of deltas under climate change, with a focus on migration and other adaptation strategies.

  12. Testicular Cancer Survivorship: Research Strategies and Recommendations

    Science.gov (United States)

    Beard, Clair; Allan, James M.; Dahl, Alv A.; Feldman, Darren R.; Oldenburg, Jan; Daugaard, Gedske; Kelly, Jennifer L.; Dolan, M. Eileen; Hannigan, Robyn; Constine, Louis S.; Oeffinger, Kevin C.; Okunieff, Paul; Armstrong, Greg; Wiljer, David; Miller, Robert C.; Gietema, Jourik A.; van Leeuwen, Flora E.; Williams, Jacqueline P.; Nichols, Craig R.; Einhorn, Lawrence H.; Fossa, Sophie D.

    2010-01-01

    Testicular cancer represents the most curable solid tumor, with a 10-year survival rate of more than 95%. Given the young average age at diagnosis, it is estimated that effective treatment approaches, in particular, platinum-based chemotherapy, have resulted in an average gain of several decades of life. This success, however, is offset by the emergence of considerable long-term morbidity, including second malignant neoplasms, cardiovascular disease, neurotoxicity, nephrotoxicity, pulmonary toxicity, hypogonadism, decreased fertility, and psychosocial problems. Data on underlying genetic or molecular factors that might identify those patients at highest risk for late sequelae are sparse. Genome-wide association studies and other translational molecular approaches now provide opportunities to identify testicular cancer survivors at greatest risk for therapy-related complications to develop evidence-based long-term follow-up guidelines and interventional strategies. We review research priorities identified during an international workshop devoted to testicular cancer survivors. Recommendations include 1) institution of lifelong follow-up of testicular cancer survivors within a large cohort setting to ascertain risks of emerging toxicities and the evolution of known late sequelae, 2) development of comprehensive risk prediction models that include treatment factors and genetic modifiers of late sequelae, 3) elucidation of the effect(s) of decades-long exposure to low serum levels of platinum, 4) assessment of the overall burden of medical and psychosocial morbidity, and 5) the eventual formulation of evidence-based long-term follow-up guidelines and interventions. Just as testicular cancer once served as the paradigm of a curable malignancy, comprehensive follow-up studies of testicular cancer survivors can pioneer new methodologies in survivorship research for all adult-onset cancer. PMID:20585105

  13. A review of second law techniques applicable to basic thermal science research

    Science.gov (United States)

    Drost, M. Kevin; Zamorski, Joseph R.

    1988-11-01

    This paper reports the results of a review of second law analysis techniques which can contribute to basic research in the thermal sciences. The review demonstrated that second law analysis has a role in basic thermal science research. Unlike traditional techniques, second law analysis accurately identifies the sources and location of thermodynamic losses. This allows the development of innovative solutions to thermal science problems by directing research to the key technical issues. Two classes of second law techniques were identified as being particularly useful. First, system and component investigations can provide information of the source and nature of irreversibilities on a macroscopic scale. This information will help to identify new research topics and will support the evaluation of current research efforts. Second, the differential approach can provide information on the causes and spatial and temporal distribution of local irreversibilities. This information enhances the understanding of fluid mechanics, thermodynamics, and heat and mass transfer, and may suggest innovative methods for reducing irreversibilities.

  14. Basic diagnosis of solid waste generated at Agua Blanca State Park to propose waste management strategies.

    Science.gov (United States)

    Laines Canepa, José Ramón; Zequeira Larios, Carolina; Valadez Treviño, Maria Elena Macías; Garduza Sánchez, Diana Ivett

    2012-03-01

    State parks are highly sensitive areas of great natural importance and tourism value. Herein a case study involving a basic survey of solid waste which was carried out in 2006 in Agua Blanca State Park, Macuspana, Tabasco, Mexico with two sampling periods representing the high and low tourist season is presented. The survey had five objectives: to find out the number of visitors in the different seasons, to consider the daily generation of solid waste from tourist activities, to determine bulk density, to select and quantify sub-products; and to suggest a possible treatment. A daily average of 368 people visited the park: 18,862 people in 14 days during the high season holiday (in just one day, Easter Sunday, up to 4425 visitors) and 2092 visitors in 43 days during the low season. The average weight of the generated solid waste was 61.267 kg day(-1) and the generated solid waste average per person was 0.155 kg person(-1 ) day(-1). During the high season, the average increased to 0.188 kg person(-1 ) day(-1) and during the low season, the average decreased to 0.144 kg person(-1 ) day(-1). The bulk density average was 75.014 kg m(-3), the maximum value was 92.472 kg m(-3) and the minimum was 68.274 kg m(-3). The sub-products comprised 54.52% inorganic matter; 32.03% organic matter, 10.60% non-recyclable and 2.85% others. Based on these results, waste management strategies such as reuse/recycling, aerobic and anaerobic digestion, the construction of a manual landfill and the employment of a specialist firm were suggested.

  15. Simulation-Based Learning Strategies to Teach Undergraduate Students Basic Surgical Skills: A Systematic Review.

    Science.gov (United States)

    Theodoulou, Iakovos; Nicolaides, Marios; Athanasiou, Thanos; Papalois, Apostolos; Sideris, Michail

    2018-02-16

    We aimed to identify and critically appraise all literature surrounding simulation-based learning (SBL) courses, to assess their relevance as tools for undergraduate surgical education, and create a design framework targeted at standardizing future SBL. We performed a systematic review of the literature using a specific keyword strategy to search at MEDLINE database. Of the 2371 potentially eligible titles, 472 were shortlisted and only 40 explored active interventions in undergraduate medical education. Of those, 20 were conducted in the United States, 9 in Europe and 11 in the rest of the world. Nineteen studies assessed the effectiveness of SBL by comparing students' attributes before and after interventions, 1 study assessed a new tool of surgical assessment and 16 studies evaluated SBL courses from the students' perspectives. Of those 40 studies, 12 used dry laboratory, 7 wet laboratory, 12 mixed, and 9 cadaveric SBL interventions. The extent to which positive results were obtained from dry, wet, mixed, and cadaveric laboratories were 75%, 57%, 92%, and 100%, respectively. Consequently, the SBL design framework was devised, providing a foundation upon which future SBL interventions can be designed such that learning outcomes are optimized. SBL is an important step in surgical education, investing in a safer and more efficient generation of surgeons. Standardization of these efforts can be accelerated with SBL design framework, a comprehensive guide to designing future interventions for basic surgical training at the undergraduate level. Copyright © 2018 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  16. Evaluation of mid-to-long term basic research for environmental restoration

    International Nuclear Information System (INIS)

    1989-09-01

    This document describes a long-term basic research program for the US Department of Energy (DOE) that complements departmental initiatives in waste management and site cleanup. The most important problems faced by DOE are environmental restoration of waste sites and cleanup of inactive facilities. Environmental restoration is defined in this report as characterization, assessment, remediation, and post-closure verification within the waste/environmental system at DOE sites. Remediation of inactive, contaminated waste-disposal sites is the largest and most expensive task facing DOE. Immobilization, isolation, separation, and destruction of waste, either aboveground or in situ, are difficult and costly tasks. Technologies for these tasks are primitive or do not exist. Departmental problems in the long term are being analyzed scientifically and research needs are being identified. When completed, the Office of Energy Research's (OER's) basis research plan will describe potential scientific research needs for universities, national laboratories, and others as a basis for research proposals to DOE. Extensive interaction with the scientific community is planned to further refine and prioritize research needs. Basic research within DOE is directed toward fundamental knowledge leading to the discovery of new scientific or engineering concepts and principles that may or may not have immediate specific technological applications. However, because DOE is a mission-oriented agency, basic research in DOE is strongly influenced by national energy and environmental policy and may be multidisciplinary in nature. Basic research will provide innovative concepts and the fundamental knowledge base that facilitates the development and application of new and emerging technologies. 41 refs., 5 figs., 9 tabs

  17. The outline report of advanced basic engineering research in the fiscal year 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-08-01

    The JNC has initiated the cooperation with universities and research institutes for advanced basic engineering on 1995. The number of research cooperation theme is increasing and satisfactorily improving in the forth year, 1998. The objective of this program is to promote the advanced basic engineering research with universities and research institutes in relation with the JNC's projects. The facilities and equipment of the JNC are mainly provided to the cooperation. The JNC has settled the research cooperation themes. The universities and research institute have applied to the themes with their issues, working plans and personnel. The JNC has selected the issues and personnel, and put into practice the cooperation with accepting guest staffs and/or research fellows from the universities. This report summarizes the results of the advanced basic engineering research cooperation executed in the fiscal year, 1998. The total number of issues is 34 for the 29 themes; those are categorized in to two groups. The one is related to the fast breeder reactor technologies and the other is on the environmental technologies. The 12 issues are finished in the fiscal year, 1998, in which the 9 issues are for the fast breeder reactor technologies and the 3 issues are for the environmental technologies. The themes/the issues, the host group, host key persons, university side key persons, a form of cooperation are summarized in the tables. The summary reports of research activities by the all cooperators are presented under the particular format. Those describe the total schedule, a form of cooperation, the research objective, the outline of research contents, main facilities for using, research status, research results, future schedules and bibliographies relevant to the research cooperation. The 25 tables and 158 figures are included. (Y. Tanaka)

  18. The outline report of advanced basic engineering research in the fiscal year 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-08-01

    The JNC has initiated the cooperation with universities and research institutes for advanced basic engineering on 1995. The number of research cooperation theme is increasing and satisfactorily improving in the forth year, 1998. The objective of this program is to promote the advanced basic engineering research with universities and research institutes in relation with the JNC's projects. The facilities and equipment of the JNC are mainly provided to the cooperation. The JNC has settled the research cooperation themes. The universities and research institute have applied to the themes with their issues, working plans and personnel. The JNC has selected the issues and personnel, and put into practice the cooperation with accepting guest staffs and/or research fellows from the universities. This report summarizes the results of the advanced basic engineering research cooperation executed in the fiscal year, 1998. The total number of issues is 34 for the 29 themes; those are categorized in to two groups. The one is related to the fast breeder reactor technologies and the other is on the environmental technologies. The 12 issues are finished in the fiscal year, 1998, in which the 9 issues are for the fast breeder reactor technologies and the 3 issues are for the environmental technologies. The themes/the issues, the host group, host key persons, university side key persons, a form of cooperation are summarized in the tables. The summary reports of research activities by the all cooperators are presented under the particular format. Those describe the total schedule, a form of cooperation, the research objective, the outline of research contents, main facilities for using, research status, research results, future schedules and bibliographies relevant to the research cooperation. The 25 tables and 158 figures are included. (Y. Tanaka)

  19. KEEP Motivational Research: Strategy and Results. Technical Report #24.

    Science.gov (United States)

    Gallimore, Ronald; Tharp, Roland G.

    This report briefly summarizes the motivation research strategy and results from the Kamehameha Early Education Program (KEEP). The rationale behind KEEP's use of on-task behavior to measure student motivation is discussed and the two strategies of motivation enhancement researched are described. These two strategies were: (1) staff training in…

  20. Empowering first year (post-matric) students in basic research skills ...

    African Journals Online (AJOL)

    Post-matric students from under-resourced (historically disadvantaged) black high schools generally encounter difficulties in their academic work at university. The study reported here was intended to empower first year (post-matric) students from these schools with basic research skills in a bid to counteract the effects of ...

  1. African American Men, Identity, and Participation in Adult Basic Education and Literacy Programs. Research Brief #6

    Science.gov (United States)

    Drayton, Brendaly; Prins, Esther

    2011-01-01

    Although the national graduation rate for African American males is only 47% (Schott Foundation for Public Education, 2010), few studies have explored their experiences in adult basic and literacy education (ABEL) programs. This study draws on prior research to explore the relationship between literacy and identity and its potential for…

  2. From Research to Practice: Basic Mathematics Skills and Success in Introductory Statistics

    Science.gov (United States)

    Lunsford, M. Leigh; Poplin, Phillip

    2011-01-01

    Based on previous research of Johnson and Kuennen (2006), we conducted a study to determine factors that would possibly predict student success in an introductory statistics course. Our results were similar to Johnson and Kuennen in that we found students' basic mathematical skills, as measured on a test created by Johnson and Kuennen, were a…

  3. Hegemonic structure of basic, clinical and patented knowledge on Ebola research: a US army reductionist initiative.

    Science.gov (United States)

    Fajardo-Ortiz, David; Ortega-Sánchez-de-Tagle, José; Castaño, Victor M

    2015-04-19

    Ebola hemorrhagic fever (Ebola) is still a highly lethal infectious disease long affecting mainly neglected populations in sub-Saharan Africa. Moreover, this disease is now considered a potential worldwide threat. In this paper, we present an approach to understand how the basic, clinical and patent knowledge on Ebola is organized and intercommunicated and what leading factor could be shaping the evolution of the knowledge translation process for this disease. A combination of citation network analysis; analysis of Medical heading Subject (MeSH) and Gene Ontology (GO) terms, and quantitative content analysis for patents and scientific literature, aimed to map the organization of Ebola research was carried out. We found six putative research fronts (i.e. clusters of high interconnected papers). Three research fronts are basic research on Ebola virus structural proteins: glycoprotein, VP40 and VP35, respectively. There is a fourth research front of basic research papers on pathogenesis, which is the organizing hub of Ebola research. A fifth research front is pre-clinical research focused on vaccines and glycoproteins. Finally, a clinical-epidemiology research front related to the disease outbreaks was identified. The network structure of patent families shows that the dominant design is the use of Ebola virus proteins as targets of vaccines and other immunological treatments. Therefore, patents network organization resembles the organization of the scientific literature. Specifically, the knowledge on Ebola would flow from higher (clinical-epidemiology) to intermediated (cellular-tissular pathogenesis) to lower (molecular interactions) levels of organization. Our results suggest a strong reductionist approach for Ebola research probably influenced by the lethality of the disease. On the other hand, the ownership profile of the patent families network and the main researches relationship with the United State Army suggest a strong involvement of this military

  4. Pluripotent stem cell-derived neural stem cells: From basic research to applications

    OpenAIRE

    Otsu, Masahiro; Nakayama, Takashi; Inoue, Nobuo

    2014-01-01

    Basic research on pluripotent stem cells is designed to enhance understanding of embryogenesis, whereas applied research is designed to develop novel therapies and prevent diseases. Attainment of these goals has been enhanced by the establishment of embryonic stem cell lines, the technological development of genomic reprogramming to generate induced-pluripotent stem cells, and improvements in vitro techniques to manipulate stem cells. This review summarizes the techniques required to generate...

  5. Research Award: Corporate Strategy and Evaluaon Division

    International Development Research Centre (IDRC) Digital Library (Canada)

    Corey Piccioni

    These one‐year, paid, in‐house programs of training and mentorship allow award ... and developmental evaluaon, to assess and adjust their program strategies? ... Be either currently enrolled at a recognized university at the master's or ...

  6. [Basic symptoms in schizophrenia, their clinical study and relevance in research].

    Science.gov (United States)

    Miret, Salvador; Fatjó-Vilas, Mar; Peralta, Víctor; Fañanás, Lourdes

    2016-01-01

    Basic symptoms consist of subtle sub-clinical disturbances subjectively experienced by schizophrenia patients. These are mainly related to drive, affect, thinking and language, perception, memory, motor action, central vegetative functions, control of cognitive processes, and stress tolerance. Initially described by Huber, from a phenomenological approach, basic symptoms are part of the earliest features of schizophrenia, and they can evolve along the course of the disorder. Their assessment during the prodromal phase of the disease (together with ultra-high risk criteria) is one of the 2 main approaches that allow the definition of states of clinical risk for the development of psychosis. The present review provides an updated view of the concept of basic symptoms, highlighting its potential value in establishing neurobiological correlates of interest in aetiopathogenic research. Copyright © 2015 SEP y SEPB. Published by Elsevier España. All rights reserved.

  7. A basic design of SR4 instrumentation and control system for research reactor

    International Nuclear Information System (INIS)

    Syahrudin Yusuf; M Subhan; Ikhsan Shobari; Sutomo Budihardjo

    2010-01-01

    An SR4 instrumentation and control systems of research reactor is the equipment of nuclear research reactors as power protection devices and control systems. The equipment is to monitor safety parameters and process parameters in the state of reactor shut down, start-up, and in operation at fixed power. In the engineering of Instrumentation and control systems SR4 research reactor, its basic design consists of technical specifications of the reactor protection system devices, technical specifications of the reactor power control system devices, technical specifications information system devices, and systems process termination cabling as a support system. This basic design is used as the basis for the preparation of detailed design and subsequent engineering development of instrumentation systems and control system integrated. (author)

  8. Supporting Knowledge Mobilization and Research Impact Strategies in Grant Applications

    Science.gov (United States)

    Phipps, David; Jensen, Krista E.; Johnny, Michael; Poetz, Anneliese

    2016-01-01

    Each application to the National Science Foundation (NSF) must contain a Broader Impact (BI) strategy. Similarly, grant applications for most research funders in Canada and the UK require strategies to support the translation of research into impacts on society; however, the guidance provided to researchers is too general to inform the specific…

  9. [Courses in basic research methodology a valuable asset for clinicians. Twelve years' experiences in southern Sweden].

    Science.gov (United States)

    Håkansson, Anders; Lindberg, Eva Pettersson; Henriksson, Karin

    2002-03-07

    At the Department of Community Medicine at Lund University we have given courses in basic research methodology since 1989. The course has yielded 20 points of university credit, the equivalent of one full-time semester of studies, and it has been run part-time, covering one and a half years. Our aim has been to provide a large number of physicians with basic training in research methods, and to stimulate the engagement of new scientific students from the whole Southern Health Care Region. During the first ten years, 138 general practitioners (20% of the GPs of the region) and 202 specialists completed our courses. Up till now, 19 GPs (14%) and 19 specialists (9%) have begun PhD studies. During the last two years, another 100 physicians from southern Sweden have attended our courses, as well as GPs from Zealand in Denmark. We have been developing our course in basic research methods during a twelve-year period, and it is now well established in our health care region. We feel that we have succeeded in reaching the two goals we had set up: to give a large number of physicians a fundamental knowledge of research methods and to recruit and increase the number of PhD students. We believe that medical research and development must flourish also outside the traditional university settings.

  10. Evaluation of the implementation of a quality system in a basic research laboratory: viability and impacts.

    Science.gov (United States)

    Fraga, Hilda Carolina de Jesus Rios; Fukutani, Kiyoshi Ferreira; Celes, Fabiana Santana; Barral, Aldina Maria Prado; Oliveira, Camila Indiani de

    2012-01-01

    To evaluate the process of implementing a quality management system in a basic research laboratory of a public institution, particularly considering the feasibility and impacts of this improvement. This was a prospective and qualitative study. We employed the norm "NIT DICLA 035--Princípios das Boas Práticas de Laboratório (BPL)" and auxiliary documents of Organisation for Economic Co-operation and Development to complement the planning and implementation of a Quality System, in a basic research laboratory. In parallel, we used the PDCA tool to define the goals of each phase of the implementation process. This study enabled the laboratory to comply with the NIT DICLA 035 norm and to implement this norm during execution of a research study. Accordingly, documents were prepared and routines were established such as the registration of non-conformities, traceability of research data and equipment calibration. The implementation of a quality system, the setting of a laboratory focused on basic research is feasible once certain structural changes are made. Importantly, impacts were noticed during the process, which could be related to several improvements in the laboratory routine.

  11. Research requirements for alternative reactor development strategies

    International Nuclear Information System (INIS)

    1979-06-01

    The purpose of this paper is to estimate and compare resource requirements and other fuel cycle quantities for alternative reactor deployment strategies. The paper examines from global and national perspectives the interaction of various fuel cycle alternatives described in the previous U.S. submissions to Working Groups 4, 5, 8 and Subgroup 1A/2A. Nuclear energy forecasts of Subgroup 1A/2A are used in the calculation of uranium demand for each strategy. These uranium demands are then compared to U.S. estimates of annual uranium producibility. Annual rather than cumulative producibility was selected because it does not assume preplanned stockpiling, and is therefore more conservative. The strategies attempt to span a range of nuclear power mixes which could evolve if appropriate commercial and governmental climates develop

  12. Basic research on intelligent robotic systems operating in hostile environments: New developments at ORNL

    International Nuclear Information System (INIS)

    Barhen, J.; Babcock, S.M.; Hamel, W.R.; Oblow, E.M.; Saridis, G.N.; deSaussure, G.; Solomon, A.D.; Weisbin, C.R.

    1984-01-01

    Robotics and artificial intelligence research carried out within the Center for Engineering Systems Advanced Research (CESAR) is presented. Activities focus on the development and demonstration of a comprehensive methodological framework for intelligent machines operating in unstructured hostile environments. Areas currently being addressed include mathematical modeling of robot dynamics, real-time control, ''world'' modeling, machine perception and strategy planning

  13. Basic researches on thermo-hydraulic non-equilibrium phenomena related to nuclear reactor safety

    International Nuclear Information System (INIS)

    Sakurai, Akira; Kataoka, Isao; Aritomi, Masanori.

    1989-01-01

    A review was made of recent developments of fundamental researches on thermo-hydraulic non-equilibrium phenomena related to light water reactor safety, in relation to problems to be solved for the improvement of safety analysis codes. As for the problems related to flow con ditions, fundamental researches on basic conservation equations and constitutive equations for transient two-phase flow were reviewed. Regarding to the problems related to thermal non-equilibrium phenomena, fundamental researches on film boiling in pool and forced convection, transient boiling heat transfer and flow behavior caused by pressure transients were reviewed. (author)

  14. The Augmented Reality Sandtable (ARES) Research Strategy

    Science.gov (United States)

    2018-02-01

    2014. Report No.: ARL-TR-6905. Creswell JW. Research design: qualitative , quantitative, and mixed methods approaches. 4th ed. Thousand Oaks (CA): Sage...an interface designed with UDOP principles. Research should seek to better understand the types of information relevant to certain classes of users...visualization research area, there are at least a few colleagues at ARL who are also conducting research in various types of (and combinations of

  15. Pedagogical workshops as a teaching and learning strategy: the hydrographic basic as a theme

    Directory of Open Access Journals (Sweden)

    Valéria Brumato Regina Fornazari

    2017-08-01

    Full Text Available Current research investigates the ideas and practices of a team of teachers of the Natural Sciences working in schools in the state of Paraná, Brazil, with regard to pedagogical workshops as teaching and learning strategies on Hydrographic Basin as theme. A continuous formation course was conducted on the theme, with data retrieved by a questionnaire applied prior to the course and after the development of workshops by the teachers. Films, recordings and descriptive memorials were analyzed according to content analysis. Results showed that teachers endeavored to problematize in the pedagogical workshops, coupled to teachers´ mediation to go beyond common sense. Students´ participation was the great progress mediated by workshops. On the other hand, interdisciplinarity and the problematization of teaching were the limiting presuppositions for their execution. The undertaking enhanced a better understanding of pedagogical workshops in the teaching of the sciences, with the need for greater investments in teachers´ continuous formation to enhance the development of teaching practices that attend to current demands in science teaching.

  16. 26 CFR 1.41-5A - Basic research for taxable years beginning before January 1, 1987.

    Science.gov (United States)

    2010-04-01

    ... TREASURY INCOME TAX INCOME TAXES Credits Against Tax § 1.41-5A Basic research for taxable years beginning... property under section 168(c) is transferred to a university for basic research on January 12, 1983, and is first so used by the university on March 1, 1983, then the research in which that property is used is...

  17. A Research on Vocabulary Teaching Strategies and Students’ Mastery

    OpenAIRE

    Tian Yuan; Liu Bingbing

    2013-01-01

    By means of questionnaire and quantitative research, this article aims at investigating the effects on students’ mastery of vocabulary by studying teachers’ adoption of seven kinds of common vocabulary teaching strategies and the usage of analyzing strategies in intensive English in order to improve vocabulary teaching strategies and to help enlarge students’ vocabulary.

  18. Transformation and communication research strategies: language - society – culture

    Directory of Open Access Journals (Sweden)

    S. M. Forkosh

    2017-06-01

    Full Text Available Main research strategies in the humanitarian sphere, connected with the transformation-communicative approach by K.-O. Apel, have been studied in the article. This approach is based on I. Kant’s classic transcendental method, but has much wider sphere of application. Syncretic tendencies in humanitarian sciences cause the search of criteria or generalizing principles, which would allow not only combining basic research strategies, but also covering variable forms of the social-dynamics. Language in its various forms becomes the common ground, where it is possible not only to describe, but to explain disparate elements of the society’s functioning. These elements, when developed, cause the formation of culture. The basis for the analysis of the interdisciplinary communication features are relevant branches of philosophy. Specific realities of the research activity are understood by the methodologist as the deep interrelation of language tools and specific features of scientific knowledge’s changes. In fact, the researcher simultaneously performs double task: interprets scientific texts, improves his/her understanding of their structural characteristics, and also studies social, cultural, humanistic priorities of the available practices. Based on the characteristics of the modern culture (rapidity of development, lack of self-awareness and «maturation» vector, non-manifestation of methodological tools, sociological and linguistic sciences become to be a model in the humanitarian area. At the same time, awareness of the structural maturation of such knowledge is low. The development of linguistic sciences has more advanced conceptual design and it resonates with the evolution of the language philosophy. That’s why, considering the socio-cultural transformations of the globalization era, grounds of clarification of the specific methodological potential, which are accumulated in the contemporary linguistics, should be considered. In this

  19. Entrepreneurial Behaviour of Researchers in a Basic Research Center the example of CERN

    CERN Document Server

    Sessano, Deborah

    2007-01-01

    The study aims to identify whether researchers' entrepreneurial behaviour changed after the introduction of a formal technology transfer policy (TTP) within CERN, the European Organization for Nuclear Research, a centre for fundamental research in particle physics. The chosen unit of analysis is the individual researcher with limited duration contract. An analysis of the background literature on entrepreneurial behaviour and factors affecting it was performed and parameters for analysis identified. A total of 103 responses to a specifically developed questionnaire were obtained and statistical analysis carried out to assess presence or absence of entrepreneurial behaviour and the factors affecting it. The theoretical framework was developed taking into account recognition by peers, network, character, prior knowledge, field of research and incentives and researchers and engineers were assessed for positive and negative correlations. One can conclude, in general, that the personnel shows a good degree of entre...

  20. U.S. nuclear reaction data program in support of basic research

    International Nuclear Information System (INIS)

    Bhat, M.R.; Chadwick, M.B.; Smith, M.S.

    1998-03-01

    Information about the US Nuclear Reaction Data Network (USNRDN) such as its members, work in progress, summaries of meetings, and organizational details may be found in its WWW Homepage. This paper is an overview of the data support provided by the network for basic research in nuclear astrophysics, radioactive ion beams, high energy heavy ion and electron interactions and related activities involving all aspects of data stewardship

  1. Basic and Applied Research at the Los Alamos Neutron Science Center

    International Nuclear Information System (INIS)

    Lisowski, P.W.

    2003-01-01

    The Los Alamos Neutron Science Center, or LANSCE, is an accelerator-based national user facility for research in basic and applied science. At present LANSCE has two experimental areas primarily using neutrons generated by 800-MeV protons striking tungsten target systems. A third area uses the proton beam for radiography. This paper describes the three LANSCE experimental areas, gives highlights of the past operating period, and discusses plans for the future

  2. Department of Energy: some aspects of basic research in the chemical sciences

    International Nuclear Information System (INIS)

    1979-01-01

    The basic research needs pertinent to DOE's specific mission are identified in the fields of combustion science, coal chemistry, reprocessing of reactor fuel and the disposal of radioactive waste, and analytical chemistry. Aspects of these fields which do not need DOE support are also identified in some cases. In addition recommendations are made on review procedures and funding, use of DOE laboratories by university and other extramural chemists, isotope availability, and critically evaluated data

  3. Basic Neuroscience Research with Nonhuman Primates: A Small but Indispensable Component of Biomedical Research

    NARCIS (Netherlands)

    Roelfsema, P.R.; Treue, S.

    2014-01-01

    Research with nonhuman primates represents a small component of neuroscience with far-reaching relevance that is irreplaceable for essential insights into cognitive functions, brain disease, and therapy. Transparency and widespread information about this research and its importance is central to

  4. Basic neuroscience research with nonhuman primates: a small but indispensable component of biomedical research

    NARCIS (Netherlands)

    Roelfsema, Pieter R.; Treue, Stefan

    2014-01-01

    Research with nonhuman primates represents a small component of neuroscience with far-reaching relevance that is irreplaceable for essential insights into cognitive functions, brain disease, and therapy. Transparency and widespread information about this research and its importance is central to

  5. Basic neuroscience research with nonhuman primates : a small but indispensable component of biomedical research

    NARCIS (Netherlands)

    Roelfsema, Pieter R; Treue, Stefan

    2014-01-01

    Research with nonhuman primates represents a small component of neuroscience with far-reaching relevance that is irreplaceable for essential insights into cognitive functions, brain disease, and therapy. Transparency and widespread information about this research and its importance is central to

  6. Student Inquiry in the Research Process: Part I: Inquiry Research Basics.

    Science.gov (United States)

    Preddy, Leslie B.

    2002-01-01

    Discusses the appropriate use of inquiry among students, teachers, and library media specialists. Topics include planning for an inquiry research project; collaboration between the library media specialist and classroom teacher; national goals, standards, and best practices; teacher roles for inquiry; and evaluating inquiry research. (LRW)

  7. A strategy for building public service motivation research Internationally

    NARCIS (Netherlands)

    Kim, S.; Vandenabeele, W.V.

    2010-01-01

    As public service motivation research grows qualitatively and quantitatively, some scholars question its appropriateness for international applications. This essay sets out a strategy of convergence for international research and measurement approaches. Studies that assess commonalities in public

  8. Research Program of Adolescent HIV Prevention Strategies | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Globally, youth aged 15 to 24 account for almost one third of all new infections. There are ... More research is needed to inform HIV prevention strategies focusing on youth. Members of the ... Institution. Ottawa Hospital Research Institute.

  9. Research Program of Adolescent HIV Prevention Strategies | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Globally, youth aged 15 to 24 account for almost one third of all new infections. There are ... More research is needed to inform HIV prevention strategies focusing on youth. Members of the ... Institution. Ottawa Hospital Research Institute.

  10. Science for Energy Technology: Strengthening the Link Between Basic Research and Industry

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-04-01

    The nation faces two severe challenges that will determine our prosperity for decades to come: assuring clean, secure, and sustainable energy to power our world, and establishing a new foundation for enduring economic and jobs growth. These challenges are linked: the global demand for clean sustainable energy is an unprecedented economic opportunity for creating jobs and exporting energy technology to the developing and developed world. But achieving the tremendous potential of clean energy technology is not easy. In contrast to traditional fossil fuel-based technologies, clean energy technologies are in their infancy, operating far below their potential, with many scientific and technological challenges to overcome. Industry is ultimately the agent for commercializing clean energy technology and for reestablishing the foundation for our economic and jobs growth. For industry to succeed in these challenges, it must overcome many roadblocks and continuously innovate new generations of renewable, sustainable, and low-carbon energy technologies such as solar energy, carbon sequestration, nuclear energy, electricity delivery and efficiency, solid state lighting, batteries and biofuels. The roadblocks to higher performing clean energy technology are not just challenges of engineering design but are also limited by scientific understanding.Innovation relies on contributions from basic research to bridge major gaps in our understanding of the phenomena that limit efficiency, performance, or lifetime of the materials or chemistries of these sustainable energy technologies. Thus, efforts aimed at understanding the scientific issues behind performance limitations can have a real and immediate impact on cost, reliability, and performance of technology, and ultimately a transformative impact on our economy. With its broad research base and unique scientific user facilities, the DOE Office of Basic Energy Sciences (BES) is ideally positioned to address these needs. BES has laid

  11. Review of the use of high potencies in basic research on homeopathy.

    Science.gov (United States)

    Clausen, Jürgen; van Wijk, Roeland; Albrecht, Henning

    2011-10-01

    The HomBRex database includes details of about 1500 basic research experiments in homeopathy. A general overview on the experiments listed in the HomBRex database is presented, focusing on high dilutions and the different settings in which those were used. Though often criticised, many experiments with remedies diluted beyond Avogadro's number demonstrate specific effects. A total of 830 experiments employing high potencies was found; in 745 experiments of these (90%), at least one positive result was reported. Animals represent the most often used model system (n=371), followed by plants (n=201), human material (n=92), bacteria and viruses (n=37) and fungi (n=32). Arsenicum album (Ars.) is the substance most often applied (n=101), followed by Sulphur (Sulph.) and Thuja (Thuj.) (n=65 and 48, respectively). Proving, prophylactic and therapeutic study designs have all been used and appear appropriate for homeopathy basic research using high dilutions. The basic research data set to support specific effects unique to high dilutions and opposite to those observed with low dilutions is, to date, insufficient. Copyright © 2011 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.

  12. Fourth annual workshop on management in basic and applied research environments

    Energy Technology Data Exchange (ETDEWEB)

    Bodnarczuk, M.W. [ed.

    1993-11-01

    The struggle to develop quality management concepts that ``map`` onto the cultural and work practices found in basic and applied research environments has been (for better or for worse) an attempt to differentiate basic and applied research from the nuclear industry. In the first (1990) edition of this ``Music Book`` proceedings, almost every laboratory that participated had a quality program that was traceable to, based on, influenced by, or in reaction to the nuclear quality standard ASME-NQA-1. This 1993 edition of the ``Music Book`` is very different in that almost every laboratory has developed a quality program that is based on, traceable to, or heavily influenced by DOE 5700.6C (Quality Assurance) and the DOE Standard; Implementation Guide for Quality Assurance Programs for Basic and Applied Research (DOE-ER-STD-6001-92). In order to construct a context for what follows and properly introduce the contents of this book, we want to briefly recount some of the highlights of the events that brought about this change, from the perspective of one who participated in the process.

  13. Mixed-methods research in pharmacy practice: basics and beyond (part 1).

    Science.gov (United States)

    Hadi, Muhammad Abdul; Alldred, David Phillip; Closs, S José; Briggs, Michelle

    2013-10-01

    This is the first of two papers which explore the use of mixed-methods research in pharmacy practice. In an era of evidence-based medicine and policy, high-quality research evidence is essential for the development of effective pharmacist-led services. Over the past decade, the use of mixed-methods research has become increasingly common in healthcare, although to date its use has been relatively limited in pharmacy practice research. In this article, the basic concepts of mixed-methods research including its definition, typologies and advantages in relation to pharmacy practice research are discussed. Mixed-methods research brings together qualitative and quantitative methodologies within a single study to answer or understand a research problem. There are a number of mixed-methods designs available, but the selection of an appropriate design must always be dictated by the research question. Importantly, mixed-methods research should not be seen as a 'tool' to collect qualitative and quantitative data, rather there should be some degree of 'integration' between the two data sets. If conducted appropriately, mixed-methods research has the potential to generate quality research evidence by combining strengths and overcoming the respective limitations of qualitative and quantitative methodologies. © 2012 Royal Pharmaceutical Society.

  14. Case study of information product for strategy research, planning research, and policy research

    International Nuclear Information System (INIS)

    Yuan Yujun; Zou Lin; Liu Qun; Wang Yongping

    2010-01-01

    Soft science research is significant and can directly support the decision-making and development. The strategy research, planning research, and policy research each play an important role in soft science research. As the National Strategy of Informatization being implemented and advanced, some progress are made and some special information tools are produced in the process of strengthening the development research with information technologies. At first, the article introduced some cases of information products application, such as the domestic and overseas information products for energy strategy research and planning research and policy research, the governmental management information system for planning and investment, examination and approval and permission system for the planning of the land for construction, China agriculture decision support system and so on, and also gave a brief analysis on the theories and methods, main functions and application status. And then, with a analysis on the features of the works of development planning of China National Nuclear Corporation (CNNC) development, this article gave some suggestions on how to strengthen the development of information system for the development planning of the CNNC. (authors)

  15. [Formal sample size calculation and its limited validity in animal studies of medical basic research].

    Science.gov (United States)

    Mayer, B; Muche, R

    2013-01-01

    Animal studies are highly relevant for basic medical research, although their usage is discussed controversially in public. Thus, an optimal sample size for these projects should be aimed at from a biometrical point of view. Statistical sample size calculation is usually the appropriate methodology in planning medical research projects. However, required information is often not valid or only available during the course of an animal experiment. This article critically discusses the validity of formal sample size calculation for animal studies. Within the discussion, some requirements are formulated to fundamentally regulate the process of sample size determination for animal experiments.

  16. Strategies and directions of Malaysian energy research

    International Nuclear Information System (INIS)

    Baharudin Yatim

    1995-01-01

    Research on energy efficiency could reconcile environmental issues associated with economic development. It could enhance energy supplies, improve the environment and develop alternative energy sources. Author reviews some of Malaysia's best energy R and D programmes

  17. An international basic science and clinical research summer program for medical students.

    Science.gov (United States)

    Ramjiawan, Bram; Pierce, Grant N; Anindo, Mohammad Iffat Kabir; Alkukhun, Abedalrazaq; Alshammari, Abdullah; Chamsi, Ahmad Talal; Abousaleh, Mohannad; Alkhani, Anas; Ganguly, Pallab K

    2012-03-01

    An important part of training the next generation of physicians is ensuring that they are exposed to the integral role that research plays in improving medical treatment. However, medical students often do not have sufficient time to be trained to carry out any projects in biomedical and clinical research. Many medical students also fail to understand and grasp translational research as an important concept today. In addition, since medical training is often an international affair whereby a medical student/resident/fellow will likely train in many different countries during his/her early training years, it is important to provide a learning environment whereby a young medical student experiences the unique challenges and value of an international educational experience. This article describes a program that bridges the gap between the basic and clinical research concepts in a unique international educational experience. After completing two semester curricula at Alfaisal University in Riyadh, Kingdom of Saudi Arabia, six medical students undertook a summer program at St. Boniface Hospital Research Centre, in Winnipeg, MB, Canada. The program lasted for 2 mo and addressed advanced training in basic science research topics in medicine such as cell isolation, functional assessment, and molecular techniques of analysis and manipulation as well as sessions on the conduct of clinical research trials, ethics, and intellectual property management. Programs such as these are essential to provide a base from which medical students can decide if research is an attractive career choice for them during their clinical practice in subsequent years. An innovative international summer research course for medical students is necessary to cater to the needs of the medical students in the 21st century.

  18. A basic condition-based maintenance strategy for air-cooled turbine generators

    International Nuclear Information System (INIS)

    Laird, T.; Griffith, G.; Hoof, M.

    2005-01-01

    This paper discusses the methods of using condition-based maintenance (CBM) for turbine generators. Even though it is focused on the maintenance strategy for air-cooled generators, all types of power producers can realize benefits from a better maintenance strategy at lower costs. A reliable assessment of the actual unit condition requires detailed knowledge of the unit design, operational weaknesses, cost of maintenance and operational capabilities. (author)

  19. The Basic Concepts Classification as a Bottom-Up Strategy for the Semantic Web

    OpenAIRE

    Rick Szostak

    2014-01-01

    The paper proposes that the Basic Concepts Classification (BCC) could serve as the controlled vocabulary for the Semantic Web. The BCC uses a synthetic approach among classes of things, relators, and properties. These are precisely the sort of concepts required by RDF triples. The BCC also addresses some of the syntactic needs of the Semantic Web. Others could be added to the BCC in a bottom‐up process that carefully evaluates the costs, benefits, and best format for each rule considered.

  20. Decision Strategy Research and Policy Support

    International Nuclear Information System (INIS)

    Hardeman, F.

    2002-01-01

    The objective of SCK-CEN's R and D programme on decision strategies and policy support is: (1) to investigate the decision making process, with all its relevant dimensions, in the context of radiation protection or other nuclear issues (with particular emphasis on emergency preparedness); (2) to disseminate knowledge on decision making and nuclear emergencies, including the organisation of training courses, the contribution to manuals or guidelines, the participation in working groups or discussion forums; (3) to assist the authorities and the industry on any topic related to radiation protection and to make expertise and infrastructure available; (4) to participate in and contribute to initiatives related to social sciences and their implementation into SCK-CEN; (5) to co-ordinate efforts of SCK-CEN related to medical applications of ionising radiation. Principal achievements in 2001 are described

  1. Decision Strategy Research and Policy Support

    Energy Technology Data Exchange (ETDEWEB)

    Hardeman, F

    2002-04-01

    The objective of SCK-CEN's R and D programme on decision strategies and policy support is: (1) to investigate the decision making process, with all its relevant dimensions, in the context of radiation protection or other nuclear issues (with particular emphasis on emergency preparedness); (2) to disseminate knowledge on decision making and nuclear emergencies, including the organisation of training courses, the contribution to manuals or guidelines, the participation in working groups or discussion forums; (3) to assist the authorities and the industry on any topic related to radiation protection and to make expertise and infrastructure available; (4) to participate in and contribute to initiatives related to social sciences and their implementation into SCK-CEN; (5) to co-ordinate efforts of SCK-CEN related to medical applications of ionising radiation. Principal achievements in 2001 are described.

  2. Microgravity: A New Tool for Basic and Applied Research in Space

    Science.gov (United States)

    1985-01-01

    This brochure highlights selected aspects of the NASA Microgravity Science and Applications program. So that we can expand our understanding and control of physical processes, this program supports basic and applied research in electronic materials, metals, glasses and ceramics, biological materials, combustion and fluids and chemicals. NASA facilities that provide weightless environments on the ground, in the air, and in space are available to U.S. and foreign investigators representing the academic and industrial communities. After a brief history of microgravity research, the text explains the advantages and methods of performing microgravity research. Illustrations follow of equipment used and experiments preformed aboard the Shuttle and of prospects for future research. The brochure concludes be describing the program goals and the opportunities for participation.

  3. Understanding asphalt compaction: An action research strategy

    NARCIS (Netherlands)

    Miller, Seirgei Rosario; ter Huerne, Henderikus L.; Doree, Andries G.; Amaratunga, Dilanthi

    2007-01-01

    In Hot Mix Asphalt (HMA) construction, rollers provide the compaction energy required to produce a specified density. However, little is known about the heuristics used by the roller operators. This study forms part of a larger action research project focussing on the improvement of the HMA paving

  4. Key Strategies for Building Research Capacity of University Faculty Members.

    Science.gov (United States)

    Huenneke, Laura F; Stearns, Diane M; Martinez, Jesse D; Laurila, Kelly

    2017-12-01

    Universities are under pressure to increase external research funding, and some federal agencies offer programs to expand research capacity in certain kinds of institutions. However, conflicts within faculty roles and other aspects of university operations influence the effectiveness of particular strategies for increasing research activity. We review conventional approaches to increasing research, focusing on outcomes for individual faculty members and use one federally-funded effort to build cancer-related research capacity at a public university as an example to explore the impact of various strategies on research outcomes. We close with hypotheses that should be tested in future formal studies.

  5. Defense, basic, and industrial research at the Los Alamos Neutron Science Center: Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Longshore, A.; Salgado, K. [comps.

    1995-10-01

    The Workshop on Defense, Basic, and Industrial Research at the Los Alamos Neutron Science Center gathered scientists from Department of Energy national laboratories, other federal institutions, universities, and industry to discuss the use of neutrons in science-based stockpile stewardship, The workshop began with presentations by government officials, senior representatives from the three weapons laboratories, and scientific opinion leaders. Workshop participants then met in breakout sessions on the following topics: materials science and engineering; polymers, complex fluids, and biomaterials; fundamental neutron physics; applied nuclear physics; condensed matter physics and chemistry; and nuclear weapons research. They concluded that neutrons can play an essential role in science-based stockpile stewardship and that there is overlap and synergy between defense and other uses of neutrons in basic, applied, and industrial research from which defense and civilian research can benefit. This proceedings is a collection of talks and papers from the plenary, technical, and breakout session presentations. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  6. Basic actinide chemistry and physics research in close cooperation with hot laboratories: ACTILAB

    International Nuclear Information System (INIS)

    Minato, K; Konashi, K; Fujii, T; Uehara, A; Nagasaki, S; Ohtori, N; Tokunaga, Y; Kambe, S

    2010-01-01

    Basic research in actinide chemistry and physics is indispensable to maintain sustainable development of innovative nuclear technology. Actinides, especially minor actinides of americium and curium, need to be handled in special facilities with containment and radiation shields. To promote and facilitate actinide research, close cooperation with the facilities and sharing of technical and scientific information must be very important and effective. A three-year-program B asic actinide chemistry and physics research in close cooperation with hot laboratories , ACTILAB, was started to form the basis of sustainable development of innovative nuclear technology. In this program, research on actinide solid-state physics, solution chemistry and solid-liquid interface chemistry is made using four main facilities in Japan in close cooperation with each other, where basic experiments with transuranium elements can be made. The 17 O-NMR measurements were performed on (Pu 0.91 Am 0.09 )O 2 to study the electronic state and the chemical behaviour of Am and Cm ions in electrolyte solutions was studied by distribution experiments.

  7. Research Strategies for Biomedical and Health Informatics

    Science.gov (United States)

    Kulikowski, Casimir A.; Bakken, Suzanne; de Lusignan, Simon; Kimura, Michio; Koch, Sabine; Mantas, John; Maojo, Victor; Marschollek, Michael; Martin-Sanchez, Fernando; Moen, Anne; Park, Hyeoun-Ae; Sarkar, Indra Neil; Leong, Tze Yun; McCray, Alexa T.

    2017-01-01

    Summary Background Medical informatics, or biomedical and health informatics (BMHI), has become an established scientific discipline. In all such disciplines there is a certain inertia to persist in focusing on well-established research areas and to hold on to well-known research methodologies rather than adopting new ones, which may be more appropriate. Objectives To search for answers to the following questions: What are research fields in informatics, which are not being currently adequately addressed, and which methodological approaches might be insufficiently used? Do we know about reasons? What could be consequences of change for research and for education? Methods Outstanding informatics scientists were invited to three panel sessions on this topic in leading international conferences (MIE 2015, Medinfo 2015, HEC 2016) in order to get their answers to these questions. Results A variety of themes emerged in the set of answers provided by the panellists. Some panellists took the theoretical foundations of the field for granted, while several questioned whether the field was actually grounded in a strong theoretical foundation. Panellists proposed a range of suggestions for new or improved approaches, methodologies, and techniques to enhance the BMHI research agenda. Conclusions The field of BMHI is on the one hand maturing as an academic community and intellectual endeavour. On the other hand vendor-supplied solutions may be too readily and uncritically accepted in health care practice. There is a high chance that BMHI will continue to flourish as an important discipline; its innovative interventions might then reach the original objectives of advancing science and improving health care outcomes. PMID:28119991

  8. Results and future plans for the innovative basic research on high temperature engineering

    International Nuclear Information System (INIS)

    2001-05-01

    The High Temperature Engineering Test Reactor (HTTR) is under the rise-to-power stage at the Oarai Research Establishment of Japan Atomic Energy Research Institute (JAERI). This reactor is aimed not only at establishment of the infrastructural technology on high temperature gas-cooled reactor and its upgrading, but also at promotion of the innovative basic research on high temperature engineering. The research is a series of innovative high-temperature irradiation studies, making the best use of the characteristic of the HTTR that it provides a very wide irradiation space at high temperatures. The JAERI has been conducting preliminary tests of the innovative research since 1994, in collaboration with universities and other research institutes, in the fields of 1) new materials development, 2) high temperature radiation chemistry and fusion-related research, and 3) high temperature irradiation techniques and other nuclear research. The HTTR Utilization Research Committee has been examining the results and methodology of the preliminary tests and the future plans, as well as examining the preparatory arrangements of facilities for the HTTR irradiation and post-irradiation examinations. This report presents a summary of results of the preliminary tests and preparatory arrangements for about seven years, together with an outline of the future plans. (author)

  9. Report on the actual state of the basic, applied research and industrial applications of the radiation in Mexico

    International Nuclear Information System (INIS)

    Lopez V, H.

    1991-07-01

    In this report the main works of basic, applied research and industrial applications that are carried out in Mexico, about radiations (radiation chemistry, technology, applications, use and isotope production, etc.): infrastructure, radiation sources, groups and research programs are presented. (Author)

  10. Ex-post evaluation. Research independency of the basic science study of JAERI

    International Nuclear Information System (INIS)

    Yanagisawa, Kazuaki; Takahashi, Shoji

    2010-06-01

    A research independency was defined here as the continuity and the development of a corresponding research field with an evolution of history. The authors took three fields as research parameters for the ex-post evaluation. They were all belonged to the basic science field studied in the Japan Atomic Energy Research Institute (JAERI). The first parameter was actinides, which was situated in the center of research networking from the viewpoint of socio-economy. The second parameter was positron, which was situated in the periphery of research networking and the third one was neutron, which had competition with other research organizations in Japan. The three were supported and promoted financially by the JAERI. The target year was covered from 1978 to 2002, a 25-years. INIS (International Nuclear Information Systems) operated by the International Atomic Energy Agency (IAEA) was used as the tool for the present bibliometric study. It was revealed that important factors that led the sustainable success of the research independency were the constant efforts to accomplish their mission, the education of their successors to instructing the explicit and tacit research findings and the construction of intellectual networking with learned circles and industries, those were in good collaboration with JAERI. These were quantitatively clarified. Conversely, main factors that impeded the development of the research independency were discontinuance of research caused by a retirement, a change of post or that of occupation, and an unexpected accident (death) of the core researchers. Among three parameters, the authors confirmed that there occurred the time-dependent stage of germination, development and declination of the research independency attributing to the interaction between the succession factors and impeded factors. For this kind of ex-post evaluation, the support of field research laboratory was inevitable. (author)

  11. SKI's research strategy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    SKI's research is a prerequisite for SKI's ability to fulfil its assignment. Research to support supervision is focused today on a number of strategically important areas such as reactor technology, material and fuel questions, human factors, waste and non-proliferation (safeguards). SKI's intelligence analysis shows that this focus should be maintained over the next few years. Some reallocation of priorities between research areas may be necessary due to changes in the nuclear area. For this research, SKI contracts universities as well as consulting companies. The resources that are of importance for nuclear research are concentrated to a few organisations in Sweden. But the national research resources alone do not cover the existing needs. One reason is that the previously highly competent and well funded Swedish expert organisations within the nuclear power utilities have gradually been phased out or transformed into consulting firms. Changes have also taken place at the Swedish vendor of boiling-water plants, now Westinghouse Atom, and the activities have been down sized considerably in Sweden. There has been a similar trend in other countries. Moreover, countries which previously conducted expensive experiments have themselves increasingly sought international support as their research resources have dwindled. As a result, numerous international projects have or are planned to be started. SKI notes that Swedish nuclear activities are also becoming increasingly dependent on international collaboration. SKI further notes that in order to fulfil its assignment, the Inspectorate needs not only financial resources but also competent personnel. This enables targeted support to be maintained to strategic national infrastructure and to international cooperation including internationally financed projects. With this is meant above all experimental research where small countries such as Sweden can join forces with other countries on to important research

  12. Status and developmental strategy of nuclear agricultural sciences in researches of eco-environmental sciences in agriculture

    International Nuclear Information System (INIS)

    Hua Luo; Wang Xunqing

    2001-01-01

    The concept, research scopes, research progress and achievement of nuclear agricultural sciences in past several decades in China, as well as the relationship between nuclear agriculture research and eco-environmental sciences were described. The disciplinary frontier, major research fields and priority developmental fields of nuclear agriculture in eco-environmental sciences was displayed. Suggestions were made to improve and strengthen nuclear agriculture research. Those provided basic source materials and consideration for application developmental strategy of nuclear agriculture in eco-environmental sciences

  13. The Basic Concepts Classification as a Bottom-Up Strategy for the Semantic Web

    Directory of Open Access Journals (Sweden)

    Rick Szostak

    2014-06-01

    Full Text Available The paper proposes that the Basic Concepts Classification (BCC could serve as the controlled vocabulary for the Semantic Web. The BCC uses a synthetic approach among classes of things, relators, and properties. These are precisely the sort of concepts required by RDF triples. The BCC also addresses some of the syntactic needs of the Semantic Web. Others could be added to the BCC in a bottom‐up process that carefully evaluates the costs, benefits, and best format for each rule considered.

  14. Low-cost USB interface for operant research using Arduino and Visual Basic.

    Science.gov (United States)

    Escobar, Rogelio; Pérez-Herrera, Carlos A

    2015-03-01

    This note describes the design of a low-cost interface using Arduino microcontroller boards and Visual Basic programming for operant conditioning research. The board executes one program in Arduino programming language that polls the state of the inputs and generates outputs in an operant chamber. This program communicates through a USB port with another program written in Visual Basic 2010 Express Edition running on a laptop, desktop, netbook computer, or even a tablet equipped with Windows operating system. The Visual Basic program controls schedules of reinforcement and records real-time data. A single Arduino board can be used to control a total of 52 inputs/output lines, and multiple Arduino boards can be used to control multiple operant chambers. An external power supply and a series of micro relays are required to control 28-V DC devices commonly used in operant chambers. Instructions for downloading and using the programs to generate simple and concurrent schedules of reinforcement are provided. Testing suggests that the interface is reliable, accurate, and could serve as an inexpensive alternative to commercial equipment. © Society for the Experimental Analysis of Behavior.

  15. Translational research needs us to go back to basics and collaborate: interview with Lars Sundstrom.

    Science.gov (United States)

    Sundstrom, Lars

    2016-09-01

    Lars Sundstrom is Director of Enterprise and Translation at the West of England Academic Health Sciences Network [1] (UK), a Professor of Practice in Translational Medicine and Co-Director of the Elizabeth Blackwell Institute for Health Research at Bristol University [2] (UK), and an honorary Professor of Medicine at Cardiff University (UK). He has extensive experience in translational medicine and clinical neurosciences, holding positions at several eminent universities. He has also held executive and board-level positions at several SMEs, developing new therapeutics for neurological conditions and tools for drug discovery. He has also been an advisor to several UK and local government task forces and to the European Commission and the European Federation of Pharmaceutical Industry Associations. He was a founding member of the European Brain Council in Brussels, and set up the Severnside Alliance for Translational Research, developing a regional network partnership to link clinical and basic scientists. He was also involved in the creation of Health Research Wales.

  16. Southern Research Station Global Change Research Strategy 2011-2019

    Science.gov (United States)

    Kier Klepzig; Zoe Hoyle; Stevin Westcott; Emrys Treasure

    2012-01-01

    In keeping with the goals of the Research and Development agenda of the Forest Service, U.S. Department of Agriculture (USDA), the Southern Research Station (SRS) provides the information and technology needed to develop best management practices for the forest lands of the Southern United States, where science-guided actions are needed to sustain ecosystem health,...

  17. New hybrid systems: strategy and research programs

    International Nuclear Information System (INIS)

    Thomas, J.B.

    2001-01-01

    This short article gives a status of research and experimental programs concerning new hybrid systems. A hybrid system is made up of a subcritical core, a spallation target and of a particle accelerator that delivers a proton beam. The main asset of hybrid systems is to provide a large reactivity margin that would be very valuable to transmute actinide nuclei efficiently. As a consequence hybrid systems could be considered as actinide burner reactors integrated to a large population of classical nuclear reactors dedicated to electricity production. (A.C.)

  18. Basic research on high-uranium density fuels for research and test reactors

    International Nuclear Information System (INIS)

    Ugajin, M.; Itoh, A.; Akabori, M.

    1992-01-01

    High-uranium density fuels, uranium silicides (U 3 Si 2 , U 3 Si) and U 6 Me-type uranium alloys (Me = Fe, Mn, Ni), were prepared and examined metallurgically as low-enriched uranium (LEU) fuels for research and test reactors. Miniature aluminum-dispersion plate-type fuel (miniplate) and aluminum-clad disk-type fuel specimens were fabricated and subjected to the neutron irradiation in JMTR (Japan Materials Testing Reactor). Fuel-aluminum compatibility tests were conducted to elucidate the extent of reaction and to identify reaction products. The relative stability of the fuels in an aluminum matrix was established at 350degC or above. Experiments were also performed to predict the chemical form of the solid fission-products in the uranium silicide (U 3 Si 2 ) simulating a high burnup anticipated for reactor service. (author)

  19. NWEA incentive strategy for wind energy. Basic data for 2007-2020

    International Nuclear Information System (INIS)

    Cleijne, H.; Verheij, F.; Coenraads, R.; Coulomb, L.; Rathmann, M.; Rooijmans, P.

    2007-01-01

    The Dutch Wind Energy Association (NWEA) aims to formulate a strategy for stimulating onshore and offshore wind energy that can be used in the political world and the government. A brief overview is provided of the main parameters that influence the development of wind energy in the Netherlands. [mk] [nl

  20. Phase-Transition-Induced Pattern Formation Applied to Basic Research on Homeopathy: A Systematic Review.

    Science.gov (United States)

    Kokornaczyk, Maria Olga; Scherr, Claudia; Bodrova, Natalia Borisovna; Baumgartner, Stephan

    2018-05-16

     Methods based on phase-transition-induced pattern formation (PTPF) are increasingly used in medical research. Frequent application fields are medical diagnosis and basic research in homeopathy. Here, we present a systematic review of experimental studies concerning PTPF-based methods applied to homeopathy research. We also aimed at categorizing the PTPF methods included in this review.  Experimental studies were collected from scientific databases (PubMed, Web of Science, Russian eLibrary) and from experts in the research field in question, following the PRISMA guidelines. The studies were rated according to pre-defined scientific criteria.  The review included 15 experimental studies. We identified seven different PTPF methods applied in 12 experimental models. Among these methods, phase-transition was triggered through evaporation, freezing, or solution, and in most cases led to the formation of crystals. First experimental studies concerning the application of PTPF methods in homeopathic research were performed in the first half of the 20th century; however, they were not continued in the following years. Only in the last decade, different research groups re-launched the idea, introducing new experimental approaches and computerized pattern evaluation techniques. The here-identified PTPF methods are for the first time proposed to be classified as one group of methods based on the same basic physical phenomenon.  Although the number of experimental studies in the area is still rather limited, the long tradition in the application of PTPF methods and the dynamics of the present developments point out the high potential of these methods and indicate that they might meet the demand for scientific methods to study potentized preparations. The Faculty of Homeopathy.

  1. MaizeGDB: The Maize Model Organism Database for Basic, Translational, and Applied Research

    OpenAIRE

    Lawrence, Carolyn J.; Harper, Lisa C.; Schaeffer, Mary L.; Sen, Taner Z.; Seigfried, Trent E.; Campbell, Darwin A.

    2008-01-01

    In 2001 maize became the number one production crop in the world with the Food and Agriculture Organization of the United Nations reporting over 614 million tonnes produced. Its success is due to the high productivity per acre in tandem with a wide variety of commercial uses. Not only is maize an excellent source of food, feed, and fuel, but also its by-products are used in the production of various commercial products. Maize's unparalleled success in agriculture stems from basic research, th...

  2. Basic and Applied Science Research at the Los Alamos Neutron Science Center

    International Nuclear Information System (INIS)

    Lisowski, Paul W.

    2005-01-01

    The Los Alamos Neutron Science Center, or LANSCE, is an accelerator-based national user facility for research in basic and applied science using four experimental areas. LANSCE has two areas that provide neutrons generated by the 800-MeV proton beam striking tungsten target systems. A third area uses the proton beam for radiography. The fourth area uses 100 MeV protons to produce medical radioisotopes. This paper describes the four LANSCE experimental areas, gives nuclear science highlights of the past operating period, and discusses plans for the future

  3. A basic research on the transient behavior for a metallic fuel FBR

    International Nuclear Information System (INIS)

    Baba, Mamoru; Hirano, Go; Kawada, Ken-ichi; Niwa, Hajime

    1999-03-01

    A metallic fuel with novel design has received great deal of interest recently as an option of advanced fuel to be substituted MOX fuel, however, the behavior at the transient has not been studied in many aspects. Therefore, for the purpose to show the basic tendency of the behavior and released energy at CDA (core disruptive accident) for a metallic fuel FBR and to prepare the basic knowledge for consideration of the adoption of the advanced fuel, Tohoku university and Power Reactor and Nuclear Fuel Development Corporation have made a joint research entitled 'A basic research on the transient behavior for a metallic fuel FBR'. The results are the following. (1) Target and Results of analysis: The accident initiator considered is a LOF accident without scram. The LOF analysis was performed for a metallic fuel 600 MWe homogeneous two region core at the beginning of cycle, both for an ordinary metallic fuel core and for a metallic fuel core with ZrH pins. It was necessary mainly to change the constants of input parameters to apply the code for the analysis of a metallic fueled reactor. These changes were made by assuming appropriate models. Basic LOF cases and all blackout case that assumed using electromagnetic pumps were analyzed. The results show that the basic LOF cases for a metallic fuel core and all the cases for a metallic fuel core with ZrH pins could be avoided to become prompt-critical, and mildly transfer to the transition phase. It is shown that the moderator is quite elective to mitigate the accident at the initiation phase. However, it is necessary to analyze the transition phase to know if the re-criticality is totally avoided after the initiation phase. (2) Improvement of CDA initiation phase analysis code: At present, it is difficult for the code to adapt to the large scale material movement in the core at the transient. Therefore, the nuclear calculation model in the code was improved by using the adiabatic space dependent kinetics, and examined

  4. Educational research in Sweden: Reform strategies and research policy

    Science.gov (United States)

    Marklund, Inger

    1981-06-01

    Educational R & D in Sweden is to a large extent policy-oriented. It has been an integrated part of the Swedish educational reform system and has brought about a dialogue between politicians, administrators and researchers. Several circumstances have contributed to the `Swedish model'. One is the system with government-appointed committees in which researchers often play an active part. Another is that the Swedish educational system is highly centralized, with the National Board of Education (NBE) as the central authority, responsible for primary, secondary and adult education. A third — and a crucial one — is that, since 1962, the NBE has had increasing funds for educational R & D at its disposal. These funds account for the main part of the economic resources for R & D, along with resources allocated to research appointments at research departments of universities. Educational R & D, conducted primarily within the NBE funds, has recently been evaluated by a government-appointed committee. In its evaluations of the impact of educational R & D, the committee distinguished between the effects of R & D and the effect correlates. It concluded that the impact of R & D is more indirect than direct, more long-term than immediate. The effects are also more easily recognized at levels above the actual school situation. This finding could be interpreted as a consequence of the policy-orientation of educational R & D, which at the same time shows the difficulties in reaching the `school level' with research and development results. There are two general trends in Sweden, which will influence both research planning and research use. First, there is a trend towards the decentralization of decision-making and responsibility for the educational system. Secondly, there is a trend towards the `sectionalization' of the R & D system as a whole. This sectionalization will mean that research will to a great extent be planned to meet needs from different parts of society — labour

  5. Research on Language Learning Strategies: Methods, Findings, and Instructional Issues.

    Science.gov (United States)

    Oxford, Rebecca; Crookall, David

    1989-01-01

    Surveys research on formal and informal second-language learning strategies, covering the effectiveness of research methods involving making lists, interviews and thinking aloud, note-taking, diaries, surveys, and training. Suggestions for future and improved research are presented. (131 references) (CB)

  6. Key Strategies for Building Research Capacity of University Faculty Members

    Science.gov (United States)

    Huenneke, Laura F.; Stearns, Diane M.; Martinez, Jesse D.; Laurila, Kelly

    2017-01-01

    Universities are under pressure to increase external research funding, and some federal agencies offer programs to expand research capacity in certain kinds of institutions. However, conflicts within faculty roles and other aspects of university operations influence the effectiveness of particular strategies for increasing research activity. We…

  7. High Level Thinking and Questioning Strategies. Research Brief

    Science.gov (United States)

    Burton, Ella

    2010-01-01

    Higher-order thinking is an instructional strategy supported by research. Often referred to as critical thinking skills, it is more than simple recall of facts or information. It is a function of the interaction between cognitive strategies, meta-cognition, and nonstrategic knowledge when solving problems. Higher-order thinking is based on the…

  8. SCORE A: A Student Research Paper Writing Strategy.

    Science.gov (United States)

    Korinek, Lori; Bulls, Jill A.

    1996-01-01

    A mnemonic strategy for writing a research paper is explained. "SCORE A" reminds the student to select a subject, create categories, obtain sources, read and take notes, evenly organize the information, and apply process writing steps. Implementation of the strategy with five eighth graders with learning disabilities is reported. (DB)

  9. Research Paper Writing Strategies of Professional Japanese EFL Writers.

    Science.gov (United States)

    Matsumoto, Kazuko

    1995-01-01

    Four Japanese university professors were interviewed on their strategies for writing a research paper in English as a Foreign Language (EFL). Results indicate that these writers use strategies similar to those used by skilled native English writers and proficient writers of English as a Second Language. (35 references) (Author/CK)

  10. What Successful Science Teachers Do: 75 Research-Based Strategies

    Science.gov (United States)

    Glasgow, Neal A.; Cheyne, Michele; Yerrick, Randy K.

    2010-01-01

    The experience and science expertise of these award-winning authors makes this easy-to-use guide a teacher's treasure trove. This latest edition to the popular What Successful Teachers Do series describes 75 research-based strategies and outlines best practices for inquiry-oriented science. Each strategy includes a brief description of the…

  11. Toward a Common Understanding of Research-Based Instructional Strategies

    Science.gov (United States)

    Goodwin, Deborah; Webb, Mary Ann

    2014-01-01

    A review of available books, articles and on-line resources which deal with "Research-Based Instructional Strategies" will produce a plethora of materials which promote the effectiveness of these strategies on student achievement. Also, a perusal of classroom instruction and teacher evaluation instruments will reveal that many of the…

  12. Basic research and industrialization of CANDU advanced fuel - A research for the improvement of RFSP code

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chang Hyo; Jang, Chang Sun; Han, Tae Young [Seoul National University, Seoul (Korea)

    2000-03-01

    The objective of this project is to improve the RFSP code by adopting three dimensional two neutron energy group model and accelerated iterative solution scheme (FDM3D) to 2 group diffusion equations as well. The major contents of this research are the derivation of the finite difference equation to three dimensional two neutron energy group diffusion equation, application of accelerated iterative solution scheme to the finite difference diffusion equation and validation of the improved RFSP code (FDM3D) through benchmark tests. We have shown that SOR/Chebyshev two parameter method and BICG-STAB/Wielandt method are more effective than that of RFSP in terms of computing speed. SOR/Chebyshev two parameter method shows better efficiency than BICG-STAB/Wielandt method. Because calculation efficiency of the latter depends on the right choice of pre-conditioner, however, it is considered that more studies are necessary to improve the efficiency of this latter method and to validate it. We have incorporated the new efficient method into the existing RFSP so that the resulting RFSP becomes much faster and more accurate. RFSP currently uses POWDERPUFS code as main lattice code, which is adequate to the neutron energy group model of RFSP. Because of this, we can not make the full advantage of advanced RFSP without adopting lattice code WIMS-AECL which can generate exact two neutron energy group constants. Therefore, we suggest developing a new CANDU design and analysis code which incorporate WIMS-AECL into FDM3D. 16 refs., 10 figs., 23 tabs. (Author)

  13. mosaicQA - A General Approach to Facilitate Basic Data Quality Assurance for Epidemiological Research.

    Science.gov (United States)

    Bialke, Martin; Rau, Henriette; Schwaneberg, Thea; Walk, Rene; Bahls, Thomas; Hoffmann, Wolfgang

    2017-05-29

    Epidemiological studies are based on a considerable amount of personal, medical and socio-economic data. To answer research questions with reliable results, epidemiological research projects face the challenge of providing high quality data. Consequently, gathered data has to be reviewed continuously during the data collection period. This article describes the development of the mosaicQA-library for non-statistical experts consisting of a set of reusable R functions to provide support for a basic data quality assurance for a wide range of application scenarios in epidemiological research. To generate valid quality reports for various scenarios and data sets, a general and flexible development approach was needed. As a first step, a set of quality-related questions, targeting quality aspects on a more general level, was identified. The next step included the design of specific R-scripts to produce proper reports for metric and categorical data. For more flexibility, the third development step focussed on the generalization of the developed R-scripts, e.g. extracting characteristics and parameters. As a last step the generic characteristics of the developed R functionalities and generated reports have been evaluated using different metric and categorical datasets. The developed mosaicQA-library generates basic data quality reports for multivariate input data. If needed, more detailed results for single-variable data, including definition of units, variables, descriptions, code lists and categories of qualified missings, can easily be produced. The mosaicQA-library enables researchers to generate reports for various kinds of metric and categorical data without the need for computational or scripting knowledge. At the moment, the library focusses on the data structure quality and supports the assessment of several quality indicators, including frequency, distribution and plausibility of research variables as well as the occurrence of missing and extreme values. To

  14. Implementing 'translational' biomedical research: convergence and divergence among clinical and basic scientists.

    Science.gov (United States)

    Morgan, Myfanwy; Barry, Christine A; Donovan, Jenny L; Sandall, Jane; Wolfe, Charles D A; Boaz, Annette

    2011-10-01

    Universities are increasingly regarded as key actors in the new 'knowledge economy', with requirements to produce market-oriented knowledge and engage in commercialization. This is of particular significance in the biomedical field, reflecting the perceived gap between success in terms of scientific discoveries and its transformation into products. The dominant discourse attributes this situation to 'blocks' in the translational pathway from 'bench to bedside', leading to policies to 'reengineer' the research enterprise. This study examines a pilot initiative established by the UK's Medical Research Council (MRC). This involved employing a change agent (Research Translator) supported by a small amount of translational funding to promote the culture and practice of translational research at a university/hospital site in England. An ethnographically informed case study involving semi-structured and open exploratory interviews, observation and document review, was conducted in 2008. Analysis and interpretation were informed by Bourdieu's logic of practice applied to science. The requirements of translational research promoted by the Research Translator and its sources of capital (authority, prestige etc) were largely congruent with the 'field' of clinical science. In contrast, translational research diverged from perceptions of 'legitimate' science and requirements for capital accumulation held by the majority of basic scientists who often described this research as 'high risk' and were resistant to the Research Translator's advice. However some differences in motivations and practices were identified within groups of scientists associated with career stage, work environment and specialty. We argue that there are convergent and divergent forces that influence scientists' readiness to adopt a market-oriented translational research model and in turn facilitate or constrain the effectiveness of a knowledge broker. We also identify ways in which current structures and

  15. Proceedings of the 109th basic science seminar on research for quantum radiation measurement

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    In the field of radiation measurement in next century, one of the main themes for researchers will be to develop new radiation detection techniques based on quantum effects. Thus three research projects for development of new neutron detection method using He-Ne laser cells, radiation-resistant optical fibers, and superconducting tunnel junction radiation detectors have been started five years before in our research group for quantum radiation measurement of the advanced science research center (ASRC) of JAERI. The joint workshop `Research for Quantum Radiation Measurement` was held as one of basic science seminars in ASRC on 19-20th of January 1998 on the occasion of the ending of the projects. There were many presentations concerning the above three themes and the participants had a good opportunity to exchange relating research information. This proceedings includes 13 papers of the presentations. It is not only useful to know the present status of advanced study but also very suggestive to see the direction and evolution of `radiation detection techniques based on quantum effects` in the future. (J.P.N.)

  16. Metabolomics and Type 2 Diabetes: Translating Basic Research into Clinical Application.

    Science.gov (United States)

    Klein, Matthias S; Shearer, Jane

    2016-01-01

    Type 2 diabetes (T2D) and its comorbidities have reached epidemic proportions, with more than half a billion cases expected by 2030. Metabolomics is a fairly new approach for studying metabolic changes connected to disease development and progression and for finding predictive biomarkers to enable early interventions, which are most effective against T2D and its comorbidities. In metabolomics, the abundance of a comprehensive set of small biomolecules (metabolites) is measured, thus giving insight into disease-related metabolic alterations. This review shall give an overview of basic metabolomics methods and will highlight current metabolomics research successes in the prediction and diagnosis of T2D. We summarized key metabolites changing in response to T2D. Despite large variations in predictive biomarkers, many studies have replicated elevated plasma levels of branched-chain amino acids and their derivatives, aromatic amino acids and α-hydroxybutyrate ahead of T2D manifestation. In contrast, glycine levels and lysophosphatidylcholine C18:2 are depressed in both predictive studies and with overt disease. The use of metabolomics for predicting T2D comorbidities is gaining momentum, as are our approaches for translating basic metabolomics research into clinical applications. As a result, metabolomics has the potential to enable informed decision-making in the realm of personalized medicine.

  17. Electronics department progress report. Basic and applied research activity 1975-1977

    International Nuclear Information System (INIS)

    1978-10-01

    The electronics department at Risoe National Laboratory, Denmark, comprises about 80 people and is made up of essentially two main divisions. One deals with the provision of instrumentation and measurement expertise for the different groups at Risoe who conduct basic research or technological R and D. This division employs a group of scientific electronics consultants, a production group, a maintenance facility and a central instrument pool for the complete site. The other division, whose work is reported here, is engaged in both basic and applied research in topics and areas of direct interest to the department itself. These involve the development and evaluation of methods, for example, in the field of plant reliability and safety as well as in a group engaged in nuclear geophysical activities - including mineral prospecting in Greenland. Another team is working with man-machine problems in highly automated systems and the associated needs for computer support in connection with proper job allocation and design. Finally, a group is active in the field of applied laser physics. The time period covered is 1975-1977. (author/BP)

  18. Metabolomics and Type 2 Diabetes: Translating Basic Research into Clinical Application

    Directory of Open Access Journals (Sweden)

    Matthias S. Klein

    2016-01-01

    Full Text Available Type 2 diabetes (T2D and its comorbidities have reached epidemic proportions, with more than half a billion cases expected by 2030. Metabolomics is a fairly new approach for studying metabolic changes connected to disease development and progression and for finding predictive biomarkers to enable early interventions, which are most effective against T2D and its comorbidities. In metabolomics, the abundance of a comprehensive set of small biomolecules (metabolites is measured, thus giving insight into disease-related metabolic alterations. This review shall give an overview of basic metabolomics methods and will highlight current metabolomics research successes in the prediction and diagnosis of T2D. We summarized key metabolites changing in response to T2D. Despite large variations in predictive biomarkers, many studies have replicated elevated plasma levels of branched-chain amino acids and their derivatives, aromatic amino acids and α-hydroxybutyrate ahead of T2D manifestation. In contrast, glycine levels and lysophosphatidylcholine C18:2 are depressed in both predictive studies and with overt disease. The use of metabolomics for predicting T2D comorbidities is gaining momentum, as are our approaches for translating basic metabolomics research into clinical applications. As a result, metabolomics has the potential to enable informed decision-making in the realm of personalized medicine.

  19. GPRA (Government Performance and Results Act) and research evaluation for basic science

    International Nuclear Information System (INIS)

    Takahashi, Shoji

    2002-08-01

    The purpose of the Government Performance and Results Act of 1993 (GPRA) is to ask federal agencies for evaluating their program performance especially from cost-efficiency aspect and to report to Congress. GPRA is to hold agencies accountable for their programs by requiring that they think strategically (in most cases every 5 years) and set, measure and report goals annually. The agencies which have responsibilities for enhancing basic science like Department of Energy (DOE) and National Science Fund (NSF) are not excluded by reasons of the difficulties of economic evaluations. In Japan, based on 'the Rationalization program for the public corporations' of 2001, the research developing type corporations should make a cost-performance evaluation in addition to the conventional ones. They have same theme as US agencies struggles. The purpose of this report is to get some hints for this theme by surveying GPRA reports of DOE and NSF and analyzing related information. At present, I have to conclude although everybody accepts the necessities of socio-economic evaluations and investment criteria for basic research, studies and discussions about ways and means are still continuing even in the US. (author)

  20. Dentistry in the future--on the role and goal of basic research in oral biology.

    Science.gov (United States)

    Mäkinen, K K

    1993-01-01

    Examination of the state of affairs of oral biology cannot be endeavoured without considering the mutual interactions and interdependencies of sciences, and without considering the impact human acts will exert on these developments. Oral biology deals with the biochemical, chemical, molecular biologic, general biologic and physical aspects of all processes that take place in the oral cavity, in the masticatory organ, and in tissues and body fluids that are associated with the above processes. Oral biology also reaps the harvest sown by (other) basic sciences. From the methodological point of view, oral biology is indistinguishable from basic sciences; it is the anatomical object that makes it specific. Oral biology cannot be regarded as "big science" (i.e. compared with the human genome project, space research, AIDS research etc.). This fact may preserve the attractiveness of oral biology. Important science--this concerns oral biology as well--still emerges in smaller settings, although there are omens that large research cartels will swallow larger and larger portions of research appropriations. A key to staying competitive is to use new science sources and--in some cases--to join bigger groups. Once upon a time oral biologists--or scientists in general--assumed that a record of solid accomplishments was sufficient to maintain research support. Today, in several countries, politics and public visibility unfortunately determine the funding privileges. Provided that human operations on earth will render future development of sciences possible, the future of oral biology will depend 1) on concomitant development in the above basic fields, and 2) on innovations in the individual psyches. This combination will unravel the structure of genes involved in the development and metabolism of oral processes, clone important salivary and connective tissue proteins, and control most important oral diseases. To achieve these goals, oral biology must attract young talent and

  1. Energy Efficiency in Building as a Basic Prerequisite for a Long Term Energy Strategies Realization, Environmental Protection and Sustainability

    International Nuclear Information System (INIS)

    Miscevic, Lj.

    2006-01-01

    Energy efficiency in buildings at the low-energy and 'passive house' standard levels is presently the basic prerequisite for considering and formulating long term strategies, which with the task of meeting energy needs and system maintenance respond to requests of environmental protection and improvements in the context of sustainable development. Orientation to sustainable development is integrated in the development strategies of Croatia. The application of renewable energy sources, in particular solar energy in passive and active systems in the architecture is permanently confirmed by conducting energy monitoring and growing number of domestic studies, projects and realizations. The long-time research project of the European Union Cost Efficient Passive Houses as European Standards (CEPHEUS) with scientific monitoring corroborated energy and economic efficiency of such architectural designs in Germany, France, Austria, and Switzerland. Thus, the 'passive house' is proposed as a standard of residential architecture, but also of the construction of other functional types of architecture in general. The accomplished energy efficiency and verified favorable profitability of investment developed new forms of incentives to low-energy and passive architecture and relevant changes in concepts of long term energy strategies in the European Union member states. In Austria the 1000th passive house was built, and the city of Frankfurt/M brought decision regarding financing building construction through the city budget at the 'passive house' level. The new Technical Regulation on energy savings and thermal protection in Croatia, which is effectively in force as of 1 July, is a long-awaited step towards energy efficiency. Although, according to this Regulation the tolerance in energy use for space heating goes, in worst case calculation, up to 89 kWh/m2 a year, any other more favorable calculation with obligation to calculate the share of solar radiation for buildings, opens

  2. The RCSB Protein Data Bank: views of structural biology for basic and applied research and education.

    Science.gov (United States)

    Rose, Peter W; Prlić, Andreas; Bi, Chunxiao; Bluhm, Wolfgang F; Christie, Cole H; Dutta, Shuchismita; Green, Rachel Kramer; Goodsell, David S; Westbrook, John D; Woo, Jesse; Young, Jasmine; Zardecki, Christine; Berman, Helen M; Bourne, Philip E; Burley, Stephen K

    2015-01-01

    The RCSB Protein Data Bank (RCSB PDB, http://www.rcsb.org) provides access to 3D structures of biological macromolecules and is one of the leading resources in biology and biomedicine worldwide. Our efforts over the past 2 years focused on enabling a deeper understanding of structural biology and providing new structural views of biology that support both basic and applied research and education. Herein, we describe recently introduced data annotations including integration with external biological resources, such as gene and drug databases, new visualization tools and improved support for the mobile web. We also describe access to data files, web services and open access software components to enable software developers to more effectively mine the PDB archive and related annotations. Our efforts are aimed at expanding the role of 3D structure in understanding biology and medicine. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

  3. New Product Development and Business Strategy of Research and Development

    International Nuclear Information System (INIS)

    Lee, Sun Cheol

    1998-05-01

    The contents of this book are new product development strategy of the top business, commercialization and new product development, development case analysis and framework of new product development, investigation strategy for idea of new product development, case analysis of research as development and goal of new product development, case analysis and planning and management for new product development, innovative item development and technical management against confusion, the map for determination procedure of development, strategy of market and goods and development strategy cases in leading company.

  4. Successive Research: A Strategy for Building on Previous Research.

    Science.gov (United States)

    Noble, Mary Anne

    1979-01-01

    Describes an approach to clinical research used by the author in teaching graduate nursing students, involving replication and expansion of a primary study of hospital intensive care units. This approach provided valuable experience as well as validated data about clinical practice. Discusses advantages and disadvantages in the approach. (MF)

  5. The long term agroecosystem research network - shared research strategy

    Science.gov (United States)

    Jean L. Steiner; Timothy Strickland; Peter J.A. Kleinman; Kris Havstad; Thomas B. Moorman; M.Susan Moran; Phil Hellman; Ray B. Bryant; David Huggins; Greg McCarty

    2016-01-01

    While current weather patterns and rapidly accelerated changes in technology often focus attention on short-term trends in agriculture, the fundamental demands on modern agriculture to meet society food, feed, fuel and fiber production while providing the foundation for a healthy environment requires long-term perspective. The Long- Term Agroecoystem Research Network...

  6. Prognosis research strategy (PROGRESS) 4: Stratified medicine research

    NARCIS (Netherlands)

    A. Hingorani (Aroon); D.A.W.M. van der Windt (Daniëlle); R.D. Riley (Richard); D. Abrams; K.G.M. Moons (Karel); E.W. Steyerberg (Ewout); S. Schroter (Sara); W. Sauerbrei (Willi); D.G. Altman (Douglas); H. Hemingway; A. Briggs (Andrew); N. Brunner; P. Croft (Peter); J. Hayden (Jill); P.A. Kyzas (Panayiotis); N. Malats (Núria); G. Peat; P. Perel (Pablo); I. Roberts (Ian); A. Timmis (Adam)

    2013-01-01

    textabstractIn patients with a particular disease or health condition, stratified medicine seeks to identify thosewho will have the most clinical benefit or least harm from a specific treatment. In this article, thefourth in the PROGRESS series, the authors discuss why prognosis research should form

  7. Basic Blue Skies Research in the UK: Are we losing out?

    Science.gov (United States)

    Linden, Belinda

    2008-02-29

    The term blue skies research implies a freedom to carry out flexible, curiosity-driven research that leads to outcomes not envisaged at the outset. This research often challenges accepted thinking and introduces new fields of study. Science policy in the UK has given growing support for short-term goal-oriented scientific research projects, with pressure being applied on researchers to demonstrate the future application of their work. These policies carry the risk of restricting freedom, curbing research direction, and stifling rather than stimulating the creativity needed for scientific discovery. This study tracks the tortuous routes that led to three major discoveries in cardiology. It then investigates the constraints in current research, and opportunities that may be lost with existing funding processes, by interviewing selected scientists and fund providers for their views on curiosity-driven research and the freedom needed to allow science to flourish. The transcripts were analysed using a grounded theory approach to gather recurrent themes from the interviews. The results from these interviews suggest that scientists often cannot predict the future applications of research. Constraints such as lack of scientific freedom, and a narrow focus on relevance and accountability were believed to stifle the discovery process. Although it was acknowledged that some research projects do need a clear and measurable framework, the interviewees saw a need for inquisitive, blue skies research to be managed in a different way. They provided examples of situations where money allocated to 'safe' funding was used for more innovative research. This sample of key UK scientists and grant providers acknowledge the importance of basic blue skies research. Yet the current evaluation process often requires that scientists predict their likely findings and estimate short-term impact, which does not permit freedom of research direction. There is a vital need for prominent scientists

  8. Planning strategies for the avoidance of pitfalls in intervention research.

    Science.gov (United States)

    Pruitt, R H; Privette, A B

    2001-08-01

    With the exception of large clinical trials, few studies in nursing and other social sciences test interventions. The discipline of nursing needs to maintain a full range of research designs for continued knowledge development. Intervention research presents unique opportunities and challenges for the novice as well as the seasoned researcher. Some of these methodological challenges include the complex nature of human subjects and interventions, including many factors that interfere with the study variables. Preliminary studies often reveal challenges that may not always be predicted or reflected in research texts. These challenges may be as important as the study results for success in future research efforts. Difficulties encountered in intervention research and suggested strategies for maintaining the integrity of the study are addressed. These challenges include maintaining an adequate sample size, intervention demands, measuring variables, timing issues, and experiencing unexpected events. Strategies presented include the importance of extensive planning, minimizing subject expectations and rewarding efforts, attention to control group members, incorporating retention strategies, expanding knowledge of variables and the study population, preliminary studies as well as anticipating unexpected events. The need for enhanced communication among nurse researchers, educators and clinicians is addressed. In the current health care arena, nurse researchers must understand organizational dynamics and marketing strategies. Collaborative research efforts can increase the visibility of nursing research as well as funding opportunities.

  9. Effective recruitment strategies in primary care research: a systematic review.

    Science.gov (United States)

    Ngune, Irene; Jiwa, Moyez; Dadich, Ann; Lotriet, Jaco; Sriram, Deepa

    2012-01-01

    Patient recruitment in primary care research is often a protracted and frustrating process, affecting project timeframes, budget and the dissemination of research findings. Yet, clear guidance on patient recruitment strategies in primary care research is limited. This paper addresses this issue through a systematic review. Articles were sourced from five academic databases - AustHealth, CINAHL, the Cochrane Methodology Group, EMBASE and PubMed/Medline; grey literature was also sourced from an academic library and the Primary Healthcare Research & Information Service (PHCRIS) website. Two reviewers independently screened the articles using the following criteria: (1) published in English, (2) reported empirical research, (3) focused on interventions designed to increase patient recruitment in primary care settings, and (4) reported patient recruitment in primary care settings. Sixty-six articles met the inclusion criteria. Of these, 23 specifically focused on recruitment strategies and included randomised trials (n = 7), systematic reviews (n = 8) and qualitative studies (n = 8). Of the remaining articles, 30 evaluated recruitment strategies, while 13 addressed the value of recruitment strategies using descriptive statistics and/or qualitative data. Among the 66 articles, primary care chiefly included general practice (n = 30); nursing and allied health services, multiple settings, as well as other community settings (n = 30); and pharmacy (n = 6). Effective recruitment strategies included the involvement of a discipline champion, simple patient eligibility criteria, patient incentives and organisational strategies that reduce practitioner workload. The most effective recruitment in primary care research requires practitioner involvement. The active participation of primary care practitioners in both the design and conduct of research helps to identify strategies that are congruent with the context in which patient care is delivered. This is reported to be the

  10. A preliminary study on radiation damage effect in ceramics composite materials as innovative basic research using the HTTR

    International Nuclear Information System (INIS)

    Ishihara, Masahiro; Baba, Shinichi; Aihara, Jun; Arai, T.; Hayashi, K.; Ishino, S.

    1999-01-01

    An innovative basic research concerning with the basic science and applied technology is planned using the High Temperature Engineering Test Reactor (HTTR), which provides the advantage of not only a high temperature irradiation field above 400degC but also a large irradiation space. The first irradiation experiment is to be performed in 2001. Many research themes with a wide variety of scientific and technological interests are proposed as the innovative basic research. For the purpose of demonstration of scientific feasibility and advantages in the HTTR irradiation, several research themes have been being conducted as the preliminary studies. In this paper the outline of the innovative basic research is described, and the preliminary study on the radiation damage mechanism of ceramic composite materials is presented. (author)

  11. Basic strategies in the electric power industry in the new competitive environment

    International Nuclear Information System (INIS)

    Ribeiro Filho, Ary Pinto; Moraes, Walter Fernando Araujo de

    1999-01-01

    This work identifies the probable strategic characteristics of the interconnected North-Northeast Brazilian electricity industry, after the current restructuring and privatization process has been implemented. It is a 15.0 thousand MW generation industry supplying more than 33.5 million consumers. The normative scenery for analysis of the electricity industry takes into consideration the premises that the government establishes the vertical separation of generation, transmission, distribution and retailing, and introduces the regulation to a competitive industrial structure in generation and retailing. It is assumed that free access to transmit and distribute electricity and broad choices for consumers are the main features for competition in both generation and retailing. The essence of formulating strategy is to relate a company with its environment, considering the industrial structure. The probable generic strategies and industrial trends are presented, and considerations are made concerned with the future expansion capacity. Finally, in the new industrial structure which will settle after the deregulation and privatization, the main strategic issues of the companies will likely focus on: profitability, cost control, managerial competence, consumer behavior, and new technologies, in special the ones related to modern thermal power plants. (author)

  12. Fiscal 2000 pioneering research on the spintronic device basic technology; 2000 nendo spintronic soshi kiban gijutsu sendo kenkyu hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Researchers specializing in technologies of magnetism or semiconductor were drafted from the industrial, official, and academic circles, who conducted hearings, patent investigations, overseas surveys, and the like, concerning spintronics. Collected in this report are the outline of the research and development of spintronic device technology, its current state and tasks and its importance from social and economic viewpoints, and the strategy that Japan should follow in the research and development of the technology. Important spintronic device technologies now attracting attention are mentioned below. The nonvolatile magnetic memory device MRAM (magnetic random access memory) is supposed to be the device which will enjoy practical application first among like devices. It is expected that the spin conduction device will lead to novel functions when the possibilities of the spin-dependent electric conduction phenomenon are further pursued. It is hoped that the spin optical device will be used as a light isolator, light spin logic device, field induced variable wavelength laser device, spin laser device, high-speed light switch, and so forth. It is necessary to watch the development of a spin-aided quantum computer which is still at the stage of basic study. (NEDO)

  13. Basic targeting strategies for rendezvous and flyby missions to the near-Earth asteroids

    Science.gov (United States)

    Perozzi, Ettore; Rossi, Alessandro; Valsecchi, Giovanni B.

    2001-01-01

    Missions to asteroids and comets are becoming increasingly feasible both from a technical and a financial point of view. In particular, those directed towards the Near-Earth Asteroids have proven suitable for a low-cost approach, thus attracting the major space agencies as well as private companies. The choice of a suitable target involves both scientific relevance and mission design considerations, being often a difficult task to accomplish due to the limited energy budget at disposal. The aim of this paper is to provide an approach to basic trajectory design which allows to account for both aspects of the problem, taking into account scientific and technical information. A global characterization of the Near-Earth Asteroids population carried out on the basis of their dynamics, physical properties and flight dynamics considerations, allows to identify a group of candidates which satisfy both, the scientific and engineering requirements. The feasibility of rendezvous and flyby missions towards them is then discussed and the possibility of repeated encounters with the same object is investigated, as an intermediate scenario. Within this framework, the capability of present and near future launch and propulsion systems for interplanetary missions is also addressed.

  14. An Analysison Provincial Medical Science Basic Research Competitiveness Based on the National Natural Science Foundation of China

    Directory of Open Access Journals (Sweden)

    Xing Xia

    2017-06-01

    Full Text Available [Purpose/significance] The National Natural Science Foundation of China (NSFC is one of the most important channels to support basic research in China. Competition for funding by the NSFC has been a very important indicator to measure the basic research level of various province and scientific research institutions. [Method/process] By combing and analyzing the status quo of NSFC in medical science, it is helpful to narrow the provincial gap and improve the basic research of medical science in China. Based on the project information of NSFC and previous scholars’ research, the paper update the index of basic research competitiveness, and analyzes project number and project funding of medical science during 2006-2016. At the same time, the competitiveness of medical science basic research and its changing trend in 31 provinces of China are analyzed. [Result/conclusion] The result shows that, in recent years, China’s basic scientific research has greatly improved, but there is a large gap between the provinces.

  15. Increasing both the public health potential of basic research and the scientist satisfaction. An international survey of bio-scientists.

    Science.gov (United States)

    Sorrentino, Carmen; Boggio, Andrea; Confalonieri, Stefano; Hemenway, David; Scita, Giorgio; Ballabeni, Andrea

    2016-01-01

    Basic scientific research generates knowledge that has intrinsic value which is independent of future applications. Basic research may also lead to practical benefits, such as a new drug or diagnostic method. Building on our previous study of basic biomedical and biological researchers at Harvard, we present findings from a new survey of similar scientists from three countries. The goal of this study was to design policies to enhance both the public health potential and the work satisfaction and test scientists' attitudes towards these factors. The present survey asked about the scientists' motivations, goals and perspectives along with their attitudes concerning  policies designed to increase both the practical (i.e. public health) benefits of basic research as well as their own personal satisfaction. Close to 900 basic investigators responded to the survey; results corroborate the main findings from the previous survey of Harvard scientists. In addition, we find that most bioscientists disfavor present policies that require a discussion of the public health potential of their proposals in grants but generally favor softer policies aimed at increasing the quality of work and the potential practical benefits of basic research. In particular, bioscientists are generally supportive of those policies entailing the organization of more meetings between scientists and the general public, the organization of more academic discussion about the role of scientists in the society, and the implementation of a "basic bibliography" for each new approved drug.

  16. QUALITATIVE STUDIES IN ACCOUNTING: THE ABDUCTIVE. RESEARCH STRATEGY.

    Directory of Open Access Journals (Sweden)

    Claudia URDARI

    2014-11-01

    Full Text Available This paper addresses to accounting researchers and proposes the use of abductive research strategy to improve the quality of accounting research outcomes. We argue that abductive reasoning has developed as a typical research method in all fields of interpretive studies but is still unrecognized by accounting researchers and practitioners. Therefore, this study aims to raise awareness on the benefits obtained through the implementation of abduction as a research strategy. Starting from Peirce (1903 and Blaikie (1993, we explore two types of abduction designs and discuss the advantages of building accounting research on grounded concepts. While this is a conceptual paper that only describes the bridge abduction reasoning can build between studying the reality and new theory emergence, we do not tackle any ethnographical case studies, social survey, or other exploratory field analyses.

  17. The Rise of Basic Research at tha Bell Labs: Young Turks and Younger Turks

    Science.gov (United States)

    Anderson, Philip

    2004-03-01

    ABSTRACT Even before World War II, a certain amount of fundamental physics research came out of the Bell Labs. Already in the 20's, before the Labs were five years old, the discoveries of electron diffraction by Davisson and Germer, and of thermal noise by Johnson and Nyquist, had come as byproducts of wide-ranging technological studies. By the late '30's, there was a small group of broadly-trained scientists who formed a nucleus around which the "young turks" in management --J B Fisk, M J Kelly, W Shockley, perhaps others--formed the postwar physical research department, comprising at first perhaps 50 people with a mandate to do exploratory but "relevant" research. This talk will diiscuss how some of the generation of postwar hires, with the cooperation of enlightened managers like W O Baker and A H White, further tested and enlarged their freedom to do basic, curiosity-driven research in an academic atmosphere. I call this group, consisting of individuals like B T Matthias, G H Wannier, R G Shulman, P A Wolff, myself , and a number of others, the "younger Turks".

  18. Universal Basic Education: An Overall Strategy of Investment Priorities for Economic Growth.

    Science.gov (United States)

    McMahon, Walter W.; Boediono

    1992-01-01

    Presents a summary of research on key aspects of the indirect effects of expanding education from grade six through grade nine, followed by a comprehensive analysis of social rates of return to investment in all levels of education in Indonesia and underemployment in urban and rural areas. (three figures, nine tables, 33 references) (MLF)

  19. Weed Control Strategies for Organic Peanut Production and Transition: A Lesson in Basic Agronomy

    Science.gov (United States)

    Weed control in organic peanut production is difficult and costly. The only production inputs that consistently improved weed management in organic peanut production were modified production practices and intense cultivation with a tine weeder. Research trials evaluated row patterns, seeding rates...

  20. The basic research on the CDA initiation phase for a metallic fuel FBR

    International Nuclear Information System (INIS)

    Hirano, Go; Hirakawa, Naohiro; Kawada, Ken-ichi; Niwa, Hazime

    1998-03-01

    A metallic fuel with novel design has received great deal of interest recently as an option of advanced fuel to be substituted MOX fuel, however, the behavior at the transient has not been studied in many aspects. Therefore, for the purpose to show the basic tendency of the behavior and released energy at CDA (core disruptive accident) for a metallic fuel FBR and to prepare the basic knowledge for consideration of the adoption of the advanced fuel, Tohoku University and Power Reactor and Nuclear Fuel Development Corporation have made a joint research entitled. (1) Target and Results of analysis: The accident initiator considered is a LOF accident with ATWS. The LOF analysis was performed for a metallic fuel 600 MWe homogeneous two region core at the beginning of cycle, both for an ordinary metallic fuel core and for a metallic fuel core with ZrH pins. It was necessary mainly to change the constants of input parameters to apply the code for the analysis of a metallic fueled reactor. These changes were made by assuming appropriate models. Basic LOF cases and all blackout case that assumed using electromagnetic pumps were analyzed. The results show that the basic LOF cases for a metallic fuel core and all the cases for a metallic fuel core with ZrH pins could be avoided to become prompt-critical, and mildly transfer to the transient phase. (2) Improvement of CDA initiation phase analysis code: At present, it is difficult for the code to adapt to the large material movement to in the core at the transient. Therefore, the nuclear calculation model in the code was improved by using the adiabatic space dependent kinetics. The results of a sample case, that is a metallic fueled core at the beginning of cycle, show this improvement is appropriate. (3) Conclusion: The behavior at CDA of a metallic fueled core of a fast reactor was analyzed using the CDA initiation phase analysis code and the knowledge of the important characteristics at the CDA initiation phase was obtained

  1. 9th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies: Basic,Epidemiologic and Clinical Research

    Science.gov (United States)

    Summary of speakers and events from the 2005 ICMAOI conference, focused on presenting basic, epidemiologic, and clinical aspects of research on malignancies in HIV-infected and other immunosuppressed individuals.

  2. 10th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies: Basic, Epidemiologic and Clinical Research

    Science.gov (United States)

    Summary of speakers and events from the 2006 ICMAOI conference, focused on presenting basic, epidemiologic, and clinical aspects of research on malignancies in HIV-infected and other immunosuppressed individuals.

  3. 4th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies: Basic,Epidemiologic and Clinical Research

    Science.gov (United States)

    Summary of speakers and events from the 2000 ICMAOI conference, focused on presenting basic, epidemiologic, and clinical aspects of research on malignancies in HIV-infected and other immunosuppressed individuals.

  4. 5th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies: Basic,Epidemiologic and Clinical Research

    Science.gov (United States)

    Summary of speakers and events from the 2005 ICMAOI conference, focused on presenting basic, epidemiologic, and clinical aspects of research on malignancies in HIV-infected and other immunosuppressed individuals.

  5. 3rd International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies: Basic,Epidemiologic and Clinical Research

    Science.gov (United States)

    Summary of speakers and events from the 1999 ICMAOI conference, focused on presenting basic, epidemiologic, and clinical aspects of research on malignancies in HIV-infected and other immunosuppressed individuals.

  6. 7th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies: Basic,Epidemiologic and Clinical Research

    Science.gov (United States)

    Summary of speakers and events from the 2003 ICMAOI conference, focused on presenting basic, epidemiologic, and clinical aspects of research on malignancies in HIV-infected and other immunosuppressed individuals.

  7. 6th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies: Basic,Epidemiologic and Clinical Research

    Science.gov (United States)

    Summary of speakers and events from the 2002 ICMAOI conference, focused on presenting basic, epidemiologic, and clinical aspects of research on malignancies in HIV-infected and other immunosuppressed individuals.

  8. Oxide dispersion strengthened ferritic steels: a basic research joint program in France

    Energy Technology Data Exchange (ETDEWEB)

    Boutard, J.-L., E-mail: jean-louis.boutard@cea.fr [Cabinet du Haut-Commissaire, CEA/Saclay, 91191 Gif sur Yvette Cedex (France); Badjeck, V. [LPS, UMR CNRS 8502, Building 510, Université Paris-Sud 11, 91405 Orsay Cedex (France); Barguet, L. [LAUM, UMR CNRS 6613, Building IAM – UFR Sciences, Avenue O. Messiaen, 72085 Le Mans Cedex 9 (France); Barouh, C. [DMN/SRMP, CEA/Saclay, Building 520, 91191 Gif sur Yvette Cedex (France); Bhattacharya, A. [DMN/SRMP, CEA/Saclay, Building 520, 91191 Gif sur Yvette Cedex (France); CSNSM, UMR CNRS 8609, Université Paris-Sud 11, Buildings 104 and 108, 91405 Orsay Campus (France); Colignon, Y. [IM2NP, UMR CNRS 7334, Case 142, Faculté des Sciences, Campus de Saint Jérôme, Aix Marseille Université, 13397 Marseille Cedex 20 (France); Hatzoglou, C. [GPM, UMR CNRS 6634, Technopôle du Madrillet, Avenue de l’Université, BP12, 76801 Saint Etienne du Rouvray Cedex (France); Loyer-Prost, M. [DMN/SRMP, CEA/Saclay, Building 520, 91191 Gif sur Yvette Cedex (France); Rouffié, A.L. [DMN/SRMA, CEA/Saclay, Building 455, 91191 Gif sur Yvette Cedex (France); Sallez, N. [SIMAP, UMR CNRS 5266, INPG, Domaine Universitaire, 1130 rue de la Piscine, BP75, 38402 Saint Martin d’Hères Cedex (France); Salmon-Legagneur, H. [DMN/SRMA, CEA/Saclay, Building 455, 91191 Gif sur Yvette Cedex (France); Schuler, T. [DMN/SRMP, CEA/Saclay, Building 520, 91191 Gif sur Yvette Cedex (France)

    2014-12-15

    AREVA, CEA, CNRS, EDF and Mécachrome are funding a joint program of basic research on Oxide Dispersion Strengthened Steels (ODISSEE), in support to the development of oxide dispersion strengthened 9–14% Cr ferritic–martensitic steels for the fuel element cladding of future Sodium-cooled fast neutron reactors. The selected objectives and the results obtained so far will be presented concerning (i) physical–chemical characterisation of the nano-clusters as a function of ball-milling process, metallurgical conditions and irradiation, (ii) meso-scale understanding of failure mechanisms under dynamic loading and creep, and, (iii) kinetic modelling of nano-clusters nucleation and α/α′ unmixing.

  9. Quantitative High Resolution Transmission Electron Microscopy (HRTEM): a novel approach towards application oriented basic research

    International Nuclear Information System (INIS)

    Kisielowski, Christian; Weber, Eicke R.; Liliental-Weber, Zuzanna

    1996-01-01

    This paper reviews recent developments of microscopic methods that base on a quantitative analysis of electron micrographs to access subsurface systems at the atomic scale. It focuses on non-equilibrium diffusion processes that are observed in nano structured MBE grown materials if a low growth temperature was used and on local deviations from a stoichiometric composition of materials. As examples we investigate Ga As/Al As and Si/Ge Si heterostructures and Ga N single crystals. The purpose of the research is twofold. On the one hand it helps understanding physical processes at the atomic scale. On the other hand we can use the results to link basic physical knowledge with the performance of semiconductor devices made from nano structured materials. (author). 28 refs., 15 figs

  10. Oxide dispersion strengthened ferritic steels: a basic research joint program in France

    Science.gov (United States)

    Boutard, J.-L.; Badjeck, V.; Barguet, L.; Barouh, C.; Bhattacharya, A.; Colignon, Y.; Hatzoglou, C.; Loyer-Prost, M.; Rouffié, A. L.; Sallez, N.; Salmon-Legagneur, H.; Schuler, T.

    2014-12-01

    AREVA, CEA, CNRS, EDF and Mécachrome are funding a joint program of basic research on Oxide Dispersion Strengthened Steels (ODISSEE), in support to the development of oxide dispersion strengthened 9-14% Cr ferritic-martensitic steels for the fuel element cladding of future Sodium-cooled fast neutron reactors. The selected objectives and the results obtained so far will be presented concerning (i) physical-chemical characterisation of the nano-clusters as a function of ball-milling process, metallurgical conditions and irradiation, (ii) meso-scale understanding of failure mechanisms under dynamic loading and creep, and, (iii) kinetic modelling of nano-clusters nucleation and α/α‧ unmixing.

  11. Oxide dispersion strengthened ferritic steels: a basic research joint program in France

    International Nuclear Information System (INIS)

    Boutard, J.-L.; Badjeck, V.; Barguet, L.; Barouh, C.; Bhattacharya, A.; Colignon, Y.; Hatzoglou, C.; Loyer-Prost, M.; Rouffié, A.L.; Sallez, N.; Salmon-Legagneur, H.; Schuler, T.

    2014-01-01

    AREVA, CEA, CNRS, EDF and Mécachrome are funding a joint program of basic research on Oxide Dispersion Strengthened Steels (ODISSEE), in support to the development of oxide dispersion strengthened 9–14% Cr ferritic–martensitic steels for the fuel element cladding of future Sodium-cooled fast neutron reactors. The selected objectives and the results obtained so far will be presented concerning (i) physical–chemical characterisation of the nano-clusters as a function of ball-milling process, metallurgical conditions and irradiation, (ii) meso-scale understanding of failure mechanisms under dynamic loading and creep, and, (iii) kinetic modelling of nano-clusters nucleation and α/α′ unmixing

  12. Guidelines for DOE Long Term Civilian Research and Development. Volume III. Basic Energy Sciences, High Energy and Nuclear Physics

    International Nuclear Information System (INIS)

    1985-12-01

    The Research Panel prepared two reports. This report reviews the Department of Energy's Basic Energy Sciences, High Energy Physics, and Nuclear Physics programs. The second report examines the Environment, Health and Safety programs in the Department. This summary addresses the general value and priority of basic research programs for the Department of Energy and the nation. In addition, it describes the key strategic issues and major recommendations for each program area

  13. Engaging workplace representatives in research: what recruitment strategies work best?

    Science.gov (United States)

    Coole, C; Nouri, F; Narayanasamy, M; Baker, P; Khan, S; Drummond, A

    2018-05-23

    Workplaces are key stakeholders in work and health but little is known about the methods used to recruit workplace representatives (WRs), including managers, occupational health advisers and colleagues, to externally funded healthcare research studies. To detail the strategies used in recruiting WRs from three areas of the UK to a qualitative study concerning their experience of employees undergoing hip or knee replacement, to compare the strategies and inform recruitment methods for future studies. Six strategies were used to recruit WRs from organizations of different sizes and sectors. Data on numbers approached and responses received were analysed descriptively. Twenty-five WRs were recruited. Recruitment had to be extended outside the main three study areas, and took several months. It proved more difficult to recruit from non-service sectors and small- and medium-sized enterprises. The most successful strategies were approaching organizations that had participated in previous research studies, or known professionally or personally to team members. Recruiting a diverse sample of WRs to healthcare research requires considerable resources and persistence, and a range of strategies. Recruitment is easier where local relationships already exist; the importance of building and maintaining these relationships cannot be underestimated. However, the potential risks of bias and participant fatigue need to be acknowledged and managed. Further studies are needed to explore how WRs can be recruited to health research, and to identify the researcher effort and costs involved in achieving unbiased and representative samples.

  14. Persistence and resistance to extinction in the domestic dog: Basic research and applications to canine training.

    Science.gov (United States)

    Hall, Nathaniel J

    2017-08-01

    This review summarizes the research investigating behavioral persistence and resistance to extinction in the dog. The first part of this paper reviews Behavioral Momentum Theory and its applications to Applied Behavior Analysis and training of pet dogs with persistent behavioral problems. I also highlight how research on Behavioral Momentum Theory can be applied to the training of detection dogs in an attempt to enhance detection performance in the presence of behavioral disruptors common in operational settings. In the second part of this review, I highlight more basic research on behavioral persistence with dogs, and how breed differences and experiences with humans as alternative sources of reinforcement can influence dogs' resistance to extinction of a target behavior. Applied Behavior Analysis and Behavior Momentum Theory have important applications for behavioral treatments to reduce the persistence of problem behavior in dogs and for the development of enhanced training methods that enhance the persistence of working dogs. Dogs can also be leveraged as natural models of stereotypic behavior and for exploring individual differences in behavioral persistence by evaluating breed and environmental variables associated with differences in canine persistance. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. It Started in a GE Freezer: Basic Precipitation Research Triggers the Business of Weather Modification

    Science.gov (United States)

    Harper, K.

    2015-12-01

    At the end of World War II, Nobel Prize-winning chemist Irving Langmuir and his team at the General Electric Research Laboratory in Schenectady, New York, were doing advanced research on cloaking smokes and aircraft icing for the US military. Trying to determine why some clouds precipitated while others did not, Langmuir concluded that non-precipitating clouds were lacking "ice nuclei" that would gather up cloud droplets until they became large enough to fall out of the cloud. If they could find an artificial substitute, it would be possible to modify clouds and the weather. Dry ice particles did the trick, military funding followed, and cloud busting commenced. But a handful of entrepreneurial meteorologists saw a different purpose: enhancing precipitation and preventing hail damage. The commercialization of weather modification was underway, with cloud seeding enhancing rainfall east of the Cascades, in the Desert Southwest, and even in the watersheds serving New York City. Hail busting took off in the Dakotas, and snowpack enhancement got a boost in Montana. Basic cloud physics research very quickly became commercial weather modification, fulfilling a postwar desire to use science and technology to control nature and creating an opening for meteorologists to provide a variety of specialized services to businesses whose profits depend on the weather.

  16. Manager's and educator's responses to the environmental challenge: the research strategy

    DEFF Research Database (Denmark)

    Madsen, Henning; Ulhøi, John Parm

    1999-01-01

    an EU research project has been carried out. The basic research strategy applied was a qualitative survey based on available secondary information and collection of primary information from companies and educational institutions. The latter information included various published material as well as semi....... The background for selecting this research strategy, how it was carried out as well as a few concentrated examples will be presented in this paper.......-structured interviews in a limited number of companies and educational institutions. By combining information from published material and interviews it was possible to formulate this part of the survey as a number of case studies. At a later stage quantitative based surveys were carried out as a supplement...

  17. Identifying research priorities for effective retention strategies in clinical trials.

    Science.gov (United States)

    Kearney, Anna; Daykin, Anne; Shaw, Alison R G; Lane, Athene J; Blazeby, Jane M; Clarke, Mike; Williamson, Paula; Gamble, Carrol

    2017-08-31

    The failure to retain patients or collect primary-outcome data is a common challenge for trials and reduces the statistical power and potentially introduces bias into the analysis. Identifying strategies to minimise missing data was the second highest methodological research priority in a Delphi survey of the Directors of UK Clinical Trial Units (CTUs) and is important to minimise waste in research. Our aim was to assess the current retention practices within the UK and priorities for future research to evaluate the effectiveness of strategies to reduce attrition. Seventy-five chief investigators of NIHR Health Technology Assessment (HTA)-funded trials starting between 2009 and 2012 were surveyed to elicit their awareness about causes of missing data within their trial and recommended practices for improving retention. Forty-seven CTUs registered within the UKCRC network were surveyed separately to identify approaches and strategies being used to mitigate missing data across trials. Responses from the current practice surveys were used to inform a subsequent two-round Delphi survey with registered CTUs. A consensus list of retention research strategies was produced and ranked by priority. Fifty out of seventy-five (67%) chief investigators and 33/47 (70%) registered CTUs completed the current practice surveys. Seventy-eight percent of trialists were aware of retention challenges and implemented strategies at trial design. Patient-initiated withdrawal was the most common cause of missing data. Registered CTUs routinely used newsletters, timeline of participant visits, and telephone reminders to mitigate missing data. Whilst 36 out of 59 strategies presented had been formally or informally evaluated, some frequently used strategies, such as site initiation training, have had no research to inform practice. Thirty-five registered CTUs (74%) participated in the Delphi survey. Research into the effectiveness of site initiation training, frequency of patient contact

  18. Fundamentos, Orientaciones, Areas Basicas y Procedimientos para la Investigacion Educativa (Bases, Guidelines, Basic Areas, and Procedures for Educational Research).

    Science.gov (United States)

    Ministerio de Educacion Nacional, Bogota (Colombia). Instituto Colombiano de Pedagogia.

    This document establishes the bases, general guidelines, basic areas, and procedures for educational research conducted in Colombia. The philosophy underlying research objectives is explained. There is special interest in social research concerning the condition of man and of the social groups that will be the targets of education, and in research…

  19. Strategies for Research, Education, and Innovation, A University's Considerations

    DEFF Research Database (Denmark)

    Møller, Jacob Steen

    2004-01-01

    Engineering (BYG•DTU) at The Technical University of Denmark (DTU) to this challenge are described: The Department has been reorganised and a new strategy has been adopted. The strategy was developed in collaboration with industry partners. The Strategy focuses on a) analysis and design of safe and economic......It is argued that the building and construction sector will maintain and even increase its economic and societal importance. In spite of this the private R&D effort in the sector is relatively modest, which in turn makes public research more important. The responds of the Department of Civil...

  20. Strategies for addressing barriers to publishing pediatric quality improvement research.

    Science.gov (United States)

    Van Cleave, Jeanne; Dougherty, Denise; Perrin, James M

    2011-09-01

    Advancing the science of quality improvement (QI) requires dissemination of the results of QI. However, the results of few QI interventions reach publication. To identify barriers to publishing results of pediatric QI research and provide practical strategies that QI researchers can use to enhance publishability of their work. We reviewed and summarized a workshop conducted at the Pediatric Academic Societies 2007 meeting in Toronto, Ontario, Canada, on conducting and publishing QI research. We also interviewed 7 experts (QI researchers, administrators, journal editors, and health services researchers who have reviewed QI manuscripts) about common reasons that QI research fails to reach publication. We also reviewed recently published pediatric QI articles to find specific examples of tactics to enhance publishability, as identified in interviews and the workshop. We found barriers at all stages of the QI process, from identifying an appropriate quality issue to address to drafting the manuscript. Strategies for overcoming these barriers included collaborating with research methodologists, creating incentives to publish, choosing a study design to include a control group, increasing sample size through research networks, and choosing appropriate process and clinical quality measures. Several well-conducted, successfully published QI studies in pediatrics offer guidance to other researchers in implementing these strategies in their own work. Specific, feasible approaches can be used to improve opportunities for publication in pediatric, QI, and general medical journals.

  1. Report of 5th new nuclear fuel research meeting, Yayoi Research Group. Trend of advanced basic research in nuclear fuel technical development

    International Nuclear Information System (INIS)

    1994-03-01

    Theme of this meeting is 'Trend of advanced basic research in nuclear fuel technical development', and it was attempted to balance both sides of the basic research and the development. At the meeting, lectures were given on the chemical form of FPs in oxide fuel pins, the absorption of hydrogen of fuel cladding tubes, the application of hydride fuel to thorium cycle, the thermal properties of fuel cladding tubes, the preparation of NpN and heat conductivity, the high temperature chemical reprocessing of nitride fuel, the research on the annihilation treatment of minor actinide in fast reactors, the separation of TRU by dry process and the annihilation using a metallic fuel FBR. In this report, the summaries of the lectures are collected, and also the program of the meeting and the list of attendants are shown. (K.I.)

  2. Problems and Guidelines of Strategy Implementation in Basic Educational Institutions under the Supervision of KhonKaen Primary Educational Service Area Office 4

    Directory of Open Access Journals (Sweden)

    Sasiwan Tonkanya

    2016-09-01

    Full Text Available The research aimed to 1 study problems of strategy implementation in basic educational institutions under Khonkaen Primary Educational Service Area Office 4 ; and 2 propose the guidelines for strategy implementation in basic educational institutions under Khonkaen Primary Educational Service Area Office 4. The study was carried out in 2 phases. In phase 1, it focused on the study and analysis of the strategic implementation problems and phase 2 studied the best practice schools. The informants for the interview in phase 1 comprised 6 school administrators and teachers who were involved in strategy implementation from small-sized, medium-sized, and large-sized schools. They were selected by the use of purposive sampling technique. The population in the study of the strategic implementation problems in basic educational institutions in phase 1 consisted of 543 school administrators and teachers who were involved in strategy implementation from 181 schools under Khonkaen Primary Educational Service Area Office 4 in academic year 2014. The study samples were 217 school administrators and teachers who were involved in strategy implementation from small-sized, medium-sized, and large-sized schools under Khonkaen Primary Educational Service Area Office 4. The samples were selected by the use of stratified sampling technique. The informants of the phase 2 study were 6 school administrators and teachers who were involved in strategy implementation from small-sized, medium-sized, and large-sized best practice schools obtained from purposive sampling technique. The research instruments used for data collection consisted of 2 sets of questionnaires. The Set 1 questionnaire was the 5-point Likert scale on the levels of the problems in implementation with item discrimination at 0.60 – 1.00 and reliability of the whole questionnaire at .9359. The questionnaire contained 3 parts with 65 items. The Set 2 questionnaire comprised 2 parts with 10 items regarding

  3. Managing scientists leadership strategies in research and development

    CERN Document Server

    Sapienza, Alice M

    1995-01-01

    Managing Scientists Leadership Strategies in Research and Development Alice M. Sapienza "I found ...this book to be exciting ...Speaking as someone who has spent 30 years grappling with these issues, I certainly would be a customer." -Robert I. Taber, PhD Senior Vice President of Research & Development Synaptic Pharmaceutical Corporation In today's climate of enormous scientific and technologic competition, it is more crucial than ever that scientists involved in research and development be managed well. Often trained as individual researchers, scientists can find integration into teams difficult. Managers, from both scientific and nonscientific backgrounds, who are responsible for these teams frequently find effective team building a long and challenging process. Managing Scientists offers strategies for fostering communication and collaboration among scientists. It shows how to build cohesive, productive, and focused teams to succeed in the competitive research and development marketplace. This book wil...

  4. New Development in NASA's Rodent Research Hardware for Conducting Long Duration Biomedical and Basic Research in Space

    Science.gov (United States)

    Shirazi-Fard, Y.; Choi, S.; Harris, C.; Gong, C.; Beegle, J. E.; Stube, K. C.; Martin, K. J.; Nevitt, R. G.; Globus, R. G.

    2017-01-01

    animals easily. The Rodent Research team has also developed Live Animal Return (LAR) capability, which will be implemented during Rodent Research-5 mission for the first time. The animals will be transported from the Habitat to a Transporter, which will return on the Dragon capsule and splashes down in the Pacific Ocean. Once SpaceX retrieves the Dragon, all powered payloads will be transferred to a SeaVan and transferred to the Long Beach pier. The NASA team then receives the transporter and delivers to a PI-designated laboratory within 120 mile radius of Long Beach. This is a significant improvement allowing researchers to examine animals within 72 hrs. of reentry or to conduct recovery experiments. Together, the hardware improvements and experience that the Rodent Research team has gained working with principal investigators and ISS crew to conduct complex experiments on orbit are expanding capabilities for long duration rodent research on the ISS to achieve both basic science and biomedical objectives.

  5. Organisational Information Security Strategy: Review, Discussion and Future Research

    Directory of Open Access Journals (Sweden)

    Craig A. Horne

    2017-05-01

    Full Text Available Dependence on information, including for some of the world’s largest organisations such as governments and multi-national corporations, has grown rapidly in recent years. However, reports of information security breaches and their associated consequences indicate that attacks are escalating on organisations conducting these information-based activities. Organisations need to formulate strategy to secure their information, however gaps exist in knowledge. Through a thematic review of academic security literature, (1 we analyse the antecedent conditions that motivate the adoption of a comprehensive information security strategy, (2 the conceptual elements of strategy and (3 the benefits that are enjoyed post-adoption. Our contributions include a definition of information security strategy that moves from an internally-focussed protection of information towards a strategic view that considers the organisation, its resources and capabilities, and its external environment. Our findings are then used to suggest future research directions.

  6. The NUTRA-SNACKS project: basic research and biotechnological programs on nutraceutics.

    Science.gov (United States)

    Rea, Giuseppina; Antonacci, Amina; Lambreva, Maya; Margonelli, Andrea; Ambrosi, Cecilia; Giardi, Maria Teresa

    2010-01-01

    The Nutra-Snacks project aims at creating novel high quality ready-to-eat foods with functional activity, useful for promoting public health. The team is composed of seven research institutes and three SMEs from different countries whose activities span from basic to applied research providing the right technological transfer to small and medium industries involved in the novel food production chain. Strategic objectives include the application of plant cell and in vitro culture systems to create very large amounts of high-value plant secondary metabolites with recognized anticancer, antilipidemic, anticholesterol, antimicrobial, antiviral, antihypertensive and anti-inflammatory properties and to include them in specific food products. To this end, the screening of a vast number of working organisms capable of accumulating the desired compounds and the characterization of their expression profiles represent fundamental steps in the research program. The information allows the identification of plant species hyper-producing metabolites and selection of those metabolites capable of specifically counteracting the oxidative stress that underlies the development of important pathologies and diseases. In addition, devising safe metabolite extraction procedures is also crucial in order to provide nutraceutical-enriched extracts compatible with human health. New biotechnological approaches are also undertaken including the exploitation of photosynthetic algal strains in bio-farms to enhance the synthesis ofantioxidant compounds and the design of novel bioreactors for small and large scale biomass production. Further outstanding objectives include the development of (i) safety and quality control protocols (ii) biosensor techniques for the analysis of the emerging ready-to-eat food and (iii) a contribution to define a standard for new regulations on nutraceutics.

  7. Large-scale User Facility Imaging and Scattering Techniques to Facilitate Basic Medical Research

    International Nuclear Information System (INIS)

    Miller, Stephen D.; Bilheux, Jean-Christophe; Gleason, Shaun Scott; Nichols, Trent L.; Bingham, Philip R.; Green, Mark L.

    2011-01-01

    Conceptually, modern medical imaging can be traced back to the late 1960's and into the early 1970's with the advent of computed tomography . This pioneering work was done by 1979 Nobel Prize winners Godfrey Hounsfield and Allan McLeod Cormack which evolved into the first prototype Computed Tomography (CT) scanner in 1971 and became commercially available in 1972. Unique to the CT scanner was the ability to utilize X-ray projections taken at regular angular increments from which reconstructed three-dimensional (3D) images could be produced. It is interesting to note that the mathematics to realize tomographic images was developed in 1917 by the Austrian mathematician Johann Radon who produced the mathematical relationships to derive 3D images from projections - known today as the Radon Transform . The confluence of newly advancing technologies, particularly in the areas of detectors, X-ray tubes, and computers combined with the earlier derived mathematical concepts ushered in a new era in diagnostic medicine via medical imaging (Beckmann, 2006). Occurring separately but at a similar time as the development of the CT scanner were efforts at the national level within the United States to produce user facilities to support scientific discovery based upon experimentation. Basic Energy Sciences within the United States Department of Energy currently supports 9 major user facilities along with 5 nanoscale science research centers dedicated to measurement sciences and experimental techniques supporting a very broad range of scientific disciplines. Tracing back the active user facilities, the Stanford Synchrotron Radiation Lightsource (SSRL) a SLAC National Accelerator Laboratory was built in 1974 and it was realized that its intense x-ray beam could be used to study protein molecular structure. The National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory was commissioned in 1982 and currently has 60 x-ray beamlines optimized for a number of different

  8. ESL Learners' Online Research and Comprehension Strategies

    Science.gov (United States)

    Sain, Noridah; Bown, Andy; Fluck, Andrew; Kebble, Paul

    2017-01-01

    In order to enhance second language (L2) acquisition, English as a Second Language (ESL) students are encouraged to exploit the abundant information and opportunities for authentic language use afforded by the Internet. This study investigated the online research and comprehension strategies employed by ESL learners in a public university in…

  9. A Critical Look at Communication Strategies: Possibilities for Future Research

    Science.gov (United States)

    Doqaruni, Vahid Rahmani

    2015-01-01

    Like general theories of human communication, previous research into second language (L2) communication strategies (CSs) has also been characterized on either interactional conceived account or cognitively conceived one. However, this paper is a critical attempt to show that CSs' full significance can only be understood if the domain of CSs…

  10. Advanced Marginality as a comparative research strategy in praxis:

    DEFF Research Database (Denmark)

    Larsen, Troels Schultz

    2018-01-01

    and homology. These concepts are applied as the foundation of a comparative research design comprising three necessary and interconnected analytical moments linking reflexivity, theory and empirical analysis. Empirically this strategy and design is confronted in the case of four Danish “Grey belt” housing...

  11. Commentary: Building Web Research Strategies for Teachers and Students

    Science.gov (United States)

    Maloy, Robert W.

    2016-01-01

    This paper presents web research strategies for teachers and students to use in building Dramatic Event, Historical Biography, and Influential Literature wiki pages for history/social studies learning. Dramatic Events refer to milestone or turning point moments in history. Historical Biographies and Influential Literature pages feature…

  12. Empowering Youth Work Supervisors with Action Research Strategies

    Science.gov (United States)

    Herman, Margo

    2012-01-01

    Supervising youth workers is a challenging, demanding job in a complex field. Too frequently youth workers get mired in reacting to the everyday crises that dominate their work, finding it difficult to rise above the daily demands to reach a place where reflection can help guide their work. Strategies based in action research can empower youth…

  13. Improving Reading Instruction through Research-Based Instructional Strategies

    Science.gov (United States)

    Nash, Vickie Lynn

    2010-01-01

    The diverse population of students in grades 1- 3 at a suburban elementary school has created a challenge for teachers when differentiating instruction in reading. The purpose of this doctoral project study was to explore the lived experiences of these teachers as they have acquired research-based instructional strategies in reading that support…

  14. Research on Adaptive Dual-Mode Switch Control Strategy for Vehicle Maglev Flywheel Battery

    Directory of Open Access Journals (Sweden)

    Hui Gao

    2015-01-01

    Full Text Available Because of the jamming signal is real-time changeable and control algorithm cannot timely tracking control flywheel rotor, this paper takes vehicle maglev flywheel battery as the research object. One kind of dual-model control strategy is developed based on the analysis of the vibration response impact of the flywheel battery control system. In view of the complex foundation vibration problems of electric vehicles, the nonlinear dynamic simulation model of vehicle maglev flywheel battery is solved. Through analyzing the nonlinear vibration response characteristics, one kind of dual-mode adaptive hybrid control strategy based on H∞ control and unbalance displacement feed-forward compensation control is presented and a real-time switch controller is designed. The reliable hybrid control is implemented, and the stability in the process of real-time switch is solved. The results of this project can provide important basic theory support for the research of vehicle maglev flywheel battery control system.

  15. [Training of institutional research networks as a strategy of improvement].

    Science.gov (United States)

    Galván-Plata, María Eugenia; Almeida-Gutiérrez, Eduardo; Salamanca-Gómez, Fabio Abdel

    2017-01-01

    The Instituto Mexicano del Seguro Social (IMSS) through the Coordinación de Investigación en Salud (Health Research Council) has promoted a strong link between the generation of scientific knowledge and the clinical care through the program Redes Institucionales de Investigación (Institutional Research Network Program), whose main aim is to promote and generate collaborative research between clinical, basic, epidemiologic, educational, economic and health services researchers, seeking direct benefits for patients, as well as to generate a positive impact on institutional processes. All of these research lines have focused on high-priority health issues in Mexico. The IMSS internal structure, as well as the sufficient health services coverage, allows the integration of researchers at the three levels of health care into these networks. A few years after their creation, these networks have already generated significant results, and these are currently applied in the institutional regulations in diseases that represent a high burden to health care. Two examples are the National Health Care Program for Patients with Acute Myocardial Infarction "Código Infarto", and the Early Detection Program on Chronic Kidney Disease; another result is the generation of multiple scientific publications, and the promotion of training of human resources in research from the same members of our Research Networks. There is no doubt that the Coordinación de Investigación en Salud advances steadily implementing the translational research, which will keep being fruitful to the benefit of our patients, and of our own institution.

  16. Why Flies? Inexpensive Public Engagement Exercises to Explain the Value of Basic Biomedical Research on "Drosophila melanogaster"

    Science.gov (United States)

    Pulver, Stefan R.; Cognigni, Paola; Denholm, Barry; Fabre, Caroline; Gu, Wendy X. W.; Linneweber, Gerit; Prieto-Godino, Lucia; Urbancic, Vasja; Zwart, Maarten; Miguel-Aliaga, Irene

    2011-01-01

    Invertebrate model organisms are powerful systems for uncovering conserved principles of animal biology. Despite widespread use in scientific communities, invertebrate research is often severely undervalued by laypeople. Here, we present a set of simple, inexpensive public outreach exercises aimed at explaining to the public why basic research on…

  17. Selected works of basic research on the physics and technology of accelerator driven clean nuclear power system

    International Nuclear Information System (INIS)

    Zhao Zhixiang

    2002-01-01

    38 theses are presented in this selected works of basic research on the physics and technology of accelerator driven clean nuclear power system. It includes reactor physics and experiment, accelerators physics and technology, nuclear physics, material research and partitioning. 13 abstracts, which has been presented on magazines home and abroad, are collected in the appendix

  18. Study of steam condensation at sub-atmospheric pressure: setting a basic research using MELCOR code

    Science.gov (United States)

    Manfredini, A.; Mazzini, M.

    2017-11-01

    One of the most serious accidents that can occur in the experimental nuclear fusion reactor ITER is the break of one of the headers of the refrigeration system of the first wall of the Tokamak. This results in water-steam mixture discharge in vacuum vessel (VV), with consequent pressurization of this container. To prevent the pressure in the VV exceeds 150 KPa absolute, a system discharges the steam inside a suppression pool, at an absolute pressure of 4.2 kPa. The computer codes used to analyze such incident (eg. RELAP 5 or MELCOR) are not validated experimentally for such conditions. Therefore, we planned a basic research, in order to have experimental data useful to validate the heat transfer correlations used in these codes. After a thorough literature search on this topic, ACTA, in collaboration with the staff of ITER, defined the experimental matrix and performed the design of the experimental apparatus. For the thermal-hydraulic design of the experiments, we executed a series of calculations by MELCOR. This code, however, was used in an unconventional mode, with the development of models suited respectively to low and high steam flow-rate tests. The article concludes with a discussion of the placement of experimental data within the map featuring the phenomenon characteristics, showing the importance of the new knowledge acquired, particularly in the case of chugging.

  19. Basic versus applied research: Julius Sachs (1832-1897) and the experimental physiology of plants.

    Science.gov (United States)

    Kutschera, Ulrich

    2015-01-01

    The German biologist Julius Sachs was the first to introduce controlled, accurate, quantitative experimentation into the botanical sciences, and is regarded as the founder of modern plant physiology. His seminal monograph Experimental-Physiologie der Pflanzen (Experimental Physiology of Plants) was published 150 y ago (1865), when Sachs was employed as a lecturer at the Agricultural Academy in Poppelsdorf/Bonn (now part of the University). This book marks the beginning of a new era of basic and applied plant science. In this contribution, I summarize the achievements of Sachs and outline his lasting legacy. In addition, I show that Sachs was one of the first biologists who integrated bacteria, which he considered to be descendants of fungi, into the botanical sciences and discussed their interaction with land plants (degradation of wood etc.). This "plant-microbe-view" of green organisms was extended and elaborated by the laboratory botanist Wilhelm Pfeffer (1845-1920), so that the term "Sachs-Pfeffer-Principle of Experimental Plant Research" appears to be appropriate to characterize this novel way of performing scientific studies on green, photoautotrophic organisms (embryophytes, algae, cyanobacteria).

  20. Establishment of International Cooperative Network and Cooperative Research Strategy Between Korea and USA on Nuclear Thermal Hydraulics

    International Nuclear Information System (INIS)

    Baek, Won Pil; Song, Chul Hwa; Jeong, Jae Jun; Choi, Ki Yong; Kang, Kyoung Ho

    2004-07-01

    1. Scope and Objectives of the Project - Successful holding of the NURETH-10 - Analysis of the international trends in technology development and applications for nuclear thermal-hydraulics - Establishment of the international cooperative network and cooperative research strategy between Korea and USA on nuclear thermal-hydraulics 2. Research Results - Successful holding of the NURETH-10 - Analysis of the international trends in technology development and applications for nuclear thermal-hydraulics: - Establishment of international cooperative network and cooperative research strategy focused between Korea and USA on nuclear thermal-hydraulics: 3. Application Plan of the Research Results - Utilization as the basic data/information in establishing the domestic R and D directions and the international cooperative research strategy, - Application of the relevant experiences and data bases of NURETH-10 for holding future international conferences, - Promote more effective and productive research cooperation between Korea and USA

  1. Research Strategies in Science-based Start-ups

    DEFF Research Database (Denmark)

    Valentin, Finn; Dahlgren, Johan Henrich; Lund Jensen, Rasmus

    develop a contingency view on complex problem solving which structures the argument into three steps:1) Characterising the problem architectures addressed by different types of DBFs;2) Testing and confirming that DBFs form requisite research strategies, by which we refer to problem solving approaches......Although biotech start-ups fail or succeed based on their research few attempts have been made to examine if and how they strategize in this core of their activity. Popular views on Dedicated Biotech Firms (DBFs) see the inherent uncertainty of research as defying notions of strategizing, directing...

  2. Bioanalytical outsourcing strategy at Janssen Research and Development.

    Science.gov (United States)

    Verhaeghe, Tom

    2014-05-01

    The times when all bioanalytical work was supported in-house are long behind us. In the modern bioanalytical laboratory, workload is divided between in-house support and outsourcing to contract research organizations. This paper outlines the outsourcing strategy of the Janssen-regulated bioanalytical group. Keeping the knowledge of the assay and the compound internally is a cornerstone of this strategy and is a driver for balancing the workload between the internal laboratory and contract laboratories. The number of contract laboratories that are being used is limited and criteria for selecting laboratories are discussed. Special attention is paid to the experience with outsourcing clinical studies to China.

  3. Adapting qualitative research strategies to technology savvy adolescents.

    Science.gov (United States)

    Mason, Deanna Marie; Ide, Bette

    2014-05-01

    To adapt research strategies involving adolescents in a grounded theory qualitative research study by conducting email rather than face-to-face interviews. Adolescent culture relies heavily on text-based communication and teens prefer interactions mediated through technology. Traditional qualitative research strategies need to be rethought when working with adolescents. Adapting interviewing strategies to electronic environments is timely and relevant for researching adolescents. Twenty three adolescents (aged 16-21) were interviewed by email. A letter of invitation was distributed. Potential participants emailed the researcher to convey interest in participating. If the inclusion criteria were met, email interviews were initiated. Participants controlled the interviews through their rate of response to interview questions. A grounded theory methodology was employed. Initial contact with participants reiterated confidentiality and the ability to withdraw from the study at any time. Interviews began with the collection of demographic information and a broad opening based on a semi-structured interview guide. All data were permissible, including text, photos, music, videos or outside media, for example YouTube. The participant was allowed to give direction to the interview after initial questions were posed. Email interviews continued until saturation was reached in the data. Participants were enthusiastic about email interviewing. Attrition did not occur. Email interviewing gave participants more control over the research, decreased power differentials between the adolescent and researcher, allowed the study to be adapted to cultural, linguistic and developmental needs, and maintained confidentiality. As participants said that email communication was slow and they preferred instant messaging, replication in faster-paced media is recommended. Repetition in face-to-face settings is warranted to evaluate how technology may have influenced the findings. Implications for

  4. Strategy for Danish wind energy research; Startegi for dansk vindenergiforskning

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    The objective of the strategy for Danish wind energy research is to support future prioritizations - primarily as regards publicly funded programs. Most recent energy political objectives formulated in 2004 by the Danish Ministry of Economic and Business Affairs state: 'The objective of the governmental energy policy is to create efficient energy markets within a framework that secures cost efficiency, security of supplies, environmental considerations and efficient use of energy. The markets must be transparent and the competition must be fair. This will secure the energy consumers the lowest possible energy prices.' The wind energy strategy mirrors user needs and is, among other things, based upon a number of interviews with interested parties and a hearing on the strategy draft. (BA)

  5. Solid state radiation chemistry. Features important in basic research and applications

    International Nuclear Information System (INIS)

    Zagorski, Z.P.

    1998-01-01

    The basic research of chemical radiation effects has been mostly proceeded in aqueous systems. When one turns from aqueous to the 'dry solute' systems, reactions are running in a very different way. The examined compound, previously the solute, becomes then the only constituent of the system, absorbing all ionising energy. Majority of dosimeters and of radiation processed systems is solid: these are crystalline or rigid substances of high viscosity, sometimes of complicated phase-compositions being no longer homogenous like liquids. Main features of the solid (and rigid) state radiation chemistry is to be discussed in five parts: I. Character of absorption process. Absorption of radiation is in all media heterogenous on the molecular level, i.e. with formation of single- and multi-ionisation spurs. The yield of the latters is 15-25% of the total ionisations, depending on the system, even at low LET radiation. In spite of random distribution of initial ionisations, the single-ionisation spurs can turn rapidly into specifically arranged, temporal localisations. The variety of spur reactions is usually more complicated than that in aqueous systems. II. Character of transients. Intermediates in solid state radiation chemistry exhibit very different transport properties: from free electrons moving fast and far, to electrons changing the position by different physicochemical mechanisms, to easy movable H-atoms, and to practically unmovable, only vibrating, new fragments of a lattice or glass. III. Paramagnetic intermediates. Radicals living for microseconds in liquids, when created and trapped in a solid matrix are usually very stable, e.g. they can have a difference of half-life times of 12 orders of magnitude, however their chemical composition remais identical. (author)

  6. Mentoring K scholars: strategies to support research mentors.

    Science.gov (United States)

    Burnham, Ellen L; Schiro, Stephanie; Fleming, Michael

    2011-06-01

    The goal of this paper is to present strategies utilized to support K scholar research mentors. K scholars are generally assistant professors who are close to developing independent research programs. Of all the various types of mentees, K scholars offer the greatest challenges, as well as the greatest rewards, for research mentors. To see one's mentee achieve independent PI status and become an established investigator is one of the great joys of being a research mentor. Research mentors for K scholars, however, may not directly benefit from their mentoring relationship, neither in terms of obtaining data to support their research program or laboratory, nor in assistance with grants or scientific papers. There is a pressing need for the research community to address the workload, institutional expectations, and reward system for research mentors. The dearth of research mentors and role models in clinical translational science parallels the decreasing number of physicians choosing careers in clinical research. While there is limited empirical information on the effectiveness of mentor support mechanisms, this white paper concludes that providing mentor support is critical to expanding the available pool of mentors, as well as providing training opportunities for K scholars. © 2011 Wiley Periodicals, Inc.

  7. Development of generalized boiling transition model applicable for wide variety of fuel bundle geometries. Basic strategy and numerical approaches

    International Nuclear Information System (INIS)

    Ninokata, Hisashi; Sadatomi, Michio; Okawa, Tomio

    2003-01-01

    In order to establish a key technology to realize advanced BWR fuel designs, a three-year project of the advanced subchannel analysis code development had been started since 2002. The five dominant factors involved in the boiling transitional process in the fuel bundles were focused. They are, (1) inter-subchannel exchanges, (2) influences of obstacles (3) dryout of liquid film, (4) transition of two-phase flow regimes and (5) deposition of droplets. It has been recognized that present physical models or constitutive equations in subchannel formulations need to be improved so that they include geometrical effects in the fuel bundle design more mechanistically and universally. Through reviewing literatures and existent experimental results, underlying elementary processes and geometrical factors that are indispensable for improving subchannel codes were identified. The basic strategy that combines numerical and experimental approaches was proposed aiming at establishment of mechanistic models for the five dominant factors. In this paper, the present status of methodologies for detailed two-phase flow studies has been summarized. According to spatial scales of focused elementary processes, proper numerical approaches were selected. For some promising numerical approaches, preliminary calcitonins were performed for assessing their applicability to investigation of elementary processes involved in the boiling transition. (author)

  8. New Informatization Strategy in the Romanian Research and Educational System

    OpenAIRE

    Ion Ivan

    2006-01-01

    There are defined the objectives, the means, the principles and the directions that must be followed by a strategy for the education and research system in Romania. There are identified the system components and the stages that must be accomplished, in order to obtain an adequate behaviour that will allow all graduate persons to become an efficient actor in the information society and to help create the basis for the new society, the knowledge oriented society.

  9. New Informatization Strategy in the Romanian Research and Educational System

    Directory of Open Access Journals (Sweden)

    Ion Ivan

    2006-10-01

    Full Text Available There are defined the objectives, the means, the principles and the directions that must be followed by a strategy for the education and research system in Romania. There are identified the system components and the stages that must be accomplished, in order to obtain an adequate behaviour that will allow all graduate persons to become an efficient actor in the information society and to help create the basis for the new society, the knowledge oriented society.

  10. Assessment Report on the national research strategy for energy

    International Nuclear Information System (INIS)

    2009-01-01

    This report was issued in 2009 by the French Parliament commission in charge of evaluating the scientific and technological choices of France's research in the field of energy. With environmental, economical and national independence concerns in view, the objective of the report is to assess the national research strategy for energy and to propose some directions for its future development. The scientific priority given in France to nuclear energy, petroleum, photovoltaic energy, second generation bio fuels and energy storage should be maintained. Mass energy storage should be considered as an essential condition for the development of renewable energies, such as offshore wind farms and storage systems

  11. Use of community engagement strategies to increase research participation in practice-based research networks (PBRNs).

    Science.gov (United States)

    Spears, William; Tsoh, Janice Y; Potter, Michael B; Weller, Nancy; Brown, Anthony E; Campbell-Voytal, Kimberly; Getrich, Christina M; Sussman, Andrew L; Pascoe, John; Neale, Anne Victoria

    2014-01-01

    Practice-based research networks (PBRNs) are increasingly encouraged to use community engagement approaches. The extent to which PBRNs engage clinic and community partners in strategies to recruit and retain participants from their local communities (specifically racial/ethnic communities) is the focus of this study. The design was a cross-sectional survey of PBRN directors in the United States. Survey respondents indicated whether their research network planned for, implemented, and has capacity for activities that engage clinic and community partners in 7 recommended strategies organized into study phases, called the cycle of trust. The objectives of the national survey were to (1) describe the extent to which PBRNs across the United States routinely implement the strategies recommended for recruiting diverse patient groups and (2) identify factors associated with implementing the recommended strategies. The survey response rate was 63%. Activities that build trust often are used more with clinic partners than with community partners. PBRNs that adopt engagement strategies when working with clinic and community partners have less difficulty in recruiting diverse populations. Multivariate analysis showed that the targeting racial/ethnic communities for study recruitment, Clinical and Translational Science Award affiliation, and planning to use community engagement strategies were independent correlates of PBRN implementation of the recommended strategies. PBRNs that successfully engage racial/ethnic communities as research partners use community engagement strategies. New commitments are needed to support PBRN researchers in developing relationships with the communities in which their patients live. Stable PBRN infrastructure funding that appreciates the value of maintaining community engagement between funded studies is critical to the research enterprise that values translating research findings into generalizable care models for patients in the community.

  12. Research on A3 steel corrosion behavior of basic magnesium sulfate cement

    Science.gov (United States)

    Xing, Sainan; Wu, Chengyou; Yu, Hongfa; Jiang, Ningshan; Zhang, Wuyu

    2017-11-01

    In this paper, Tafel polarization technique is used to study the corrosion behavior of A3 steel basic magnesium sulfate, and then analyzing the ratio of raw materials cement, nitrites rust inhibitor and wet-dry cycle of basic magnesium sulfate corrosion of reinforced influence, and the steel corrosion behavior of basic magnesium sulfate compared with magnesium oxychloride cement and Portland cement. The results show that: the higher MgO/MgSO4 mole ratio will reduce the corrosion rate of steel; Too high and too low H2O/MgSO4 mole ratio may speed up the reinforcement corrosion effect; Adding a small amount of nitrite rust and corrosion inhibitor, not only can obviously reduce the alkali type magnesium sulfate in the early hydration of cement steel bar corrosion rate, but also can significantly reduce dry-wet circulation under the action of alkali type magnesium sulfate cement corrosion of reinforcement effect. Basic magnesium sulfate cement has excellent ability to protect reinforced, its long-term corrosion of reinforcement effect and was equal to that of Portland cement. Basic magnesium sulfate corrosion of reinforced is far below the level in the MOC in the case.

  13. Fundamentals in Biostatistics for Research in Pediatric Dentistry: Part I - Basic Concepts.

    Science.gov (United States)

    Garrocho-Rangel, J A; Ruiz-Rodríguez, M S; Pozos-Guillén, A J

    The purpose of this report was to provide the reader with some basic concepts in order to better understand the significance and reliability of the results of any article on Pediatric Dentistry. Currently, Pediatric Dentists need the best evidence available in the literature on which to base their diagnoses and treatment decisions for the children's oral care. Basic understanding of Biostatistics plays an important role during the entire Evidence-Based Dentistry (EBD) process. This report describes Biostatistics fundamentals in order to introduce the basic concepts used in statistics, such as summary measures, estimation, hypothesis testing, effect size, level of significance, p value, confidence intervals, etc., which are available to Pediatric Dentists interested in reading or designing original clinical or epidemiological studies.

  14. Differences in citation frequency of clinical and basic science papers in cardiovascular research.

    Science.gov (United States)

    Opthof, Tobias

    2011-06-01

    In this article, a critical analysis is performed on differences in citation frequency of basic and clinical cardiovascular papers. It appears that the latter papers are cited at about 40% higher frequency. The differences between the largest number of citations of the most cited papers are even larger. It is also demonstrated that the groups of clinical and basic cardiovascular papers are also heterogeneous concerning citation frequency. It is concluded that none of the existing citation indicators appreciates these differences. At this moment these indicators should not be used for quality assessment of individual scientists and scientific niches with small numbers of scientists.

  15. R5T4 compounds - unique multifunctional intermetallics for basic research and applications

    Energy Technology Data Exchange (ETDEWEB)

    Mudryk, Yaroslav

    2016-10-01

    The unique properties of the rare-earth elements and their alloys have brought them from relative obscurity to high profile use in common high-tech applications. The broad technological impact of these remarkable materials may have never been known by the general public if not for the supply concerns that placed the rare-earth materials on the front page of newspapers and magazines. Neodymium and dysprosium, two essential components of Nd2Fe14B-based high-performance permanent magnets, have drawn much attention and have been deemed critical materials for many energy-related applications. Ironically, the notoriety of rare-earth elements and their alloys is the result of a global movement to reduce their use in industrial applications and, thus, ease concerns about their supply and ultimately to reduce their position in high-tech supply chains. Research into the applications of lanthanide alloys has been de-emphasized recently due to the perception that industry is moving away from the use of rare-earth elements in new products. While lanthanide supply challenges justify efforts to diversify the supply chain, a strategy to completely replace the materials overlooks the reasons rare earths became important in the first place -- their unique properties are too beneficial to ignore. Rare-earth alloys and compounds possess truly exciting potential for basic science exploration and application development such as solid-state caloric cooling. In this brief review, we touch upon several promising systems containing lanthanide elements that show important and interesting magnetism-related phenomena.

  16. Proceeding on the scientific meeting and presentation on basic research of nuclear science and technology (book I): physics, reactors

    International Nuclear Information System (INIS)

    Syarip; Prayitno; Samin; Agus Taftazani; Sudjatmoko; Pramudita Anggraita; Gede Sutresna W; Tjipto Sujitno; Slamet Santosa; Herry Poernomo; R Sukarsono; Prajitno

    2014-06-01

    Scientific Meeting and Presentation on Basic Research in Nuclear Science and Technology is an annual activity held by Centre for Accelerator Science and Technology, National Nuclear Energy Agency, in Yogyakarta, for monitoring research activities achieved by the Agency. The papers presented in the meeting were collected into proceedings which were divided into two groups that are physics and nuclear reactors. The proceedings consists of three articles from keynote speakers and 25 articles from BATAN and others participants.(PPIKSN)

  17. Strategies for research engagement of clinicians in allied health (STRETCH): a mixed methods research protocol.

    Science.gov (United States)

    Mickan, Sharon; Wenke, Rachel; Weir, Kelly; Bialocerkowski, Andrea; Noble, Christy

    2017-09-11

    Allied health professionals (AHPs) report positive attitudes to using research evidence in clinical practice, yet often lack time, confidence and skills to use, participate in and conduct research. A range of multifaceted strategies including education, mentoring and guidance have been implemented to increase AHPs' use of and participation in research. Emerging evidence suggests that knowledge brokering activities have the potential to support research engagement, but it is not clear which knowledge brokering strategies are most effective and in what contexts they work best to support and maintain clinicians' research engagement. This protocol describes an exploratory concurrent mixed methods study that is designed to understand how allied health research fellows use knowledge brokering strategies within tailored evidence-based interventions, to facilitate research engagement by allied health clinicians. Simultaneously, a realist approach will guide a systematic process evaluation of the research fellows' pattern of use of knowledge brokering strategies within each case study to build a programme theory explaining which knowledge brokering strategies work best, in what contexts and why. Learning and behavioural theories will inform this critical explanation. An explanation of how locally tailored evidence-based interventions improve AHPs use of, participation in and leadership of research projects will be summarised and shared with all participating clinicians and within each case study. It is expected that local recommendations will be developed and shared with medical and nursing professionals in and beyond the health service, to facilitate building research capacity in a systematic and effective way. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  18. Synchrotron radiation, a powerful tool in research and technological development. Basic principles

    International Nuclear Information System (INIS)

    Jimenez M, J.

    2001-01-01

    The basic principles of synchrotron radiation emission in electron accelerators are presented. The main characteristics of synchrotron radiation, together with the physical principles that describe its interaction with different materials are also discussed. Different areas in which the development of synchrotron radiation has made a major impact are given. (Author)

  19. Centro de Biologia Molecular "Severo Ochoa": a center for basic research into Alzheimer's disease.

    Science.gov (United States)

    Avila, Jesus; Hernandez, Felix; Wandosell, Francisco; Lucas, Jose J; Esteban, Jose A; Ledesma, M Dolores; Bullido, Maria J

    2010-01-01

    One important aspect of studies carried out at the Center for Molecular Biology "Severo Ochoa" is focused on basic aspects of Alzheimer's disease, mainly the search for suitable therapeutic targets for this disorder. Several groups at the Center are involved in these studies, and, in this spotlight, the work they are carrying out will be described.

  20. Research and Practice on Basic Composition and Cultivation Pattern of College Students' Innovative Ability

    Science.gov (United States)

    Xu, Zhenhui; Chen, Hanlin

    2010-01-01

    Facing the increasingly fierce international competition, it has been the core of higher education to explore how to cultivate college students with innovative ability. College students' innovative ability is mainly composed of basic ability, innovative thinking and innovative actions. In conformity to the above composition, the cultivation…

  1. Translating Basic Behavioral and Social Science Research to Clinical Application: The EVOLVE Mixed Methods Approach

    Science.gov (United States)

    Peterson, Janey C.; Czajkowski, Susan; Charlson, Mary E.; Link, Alissa R.; Wells, Martin T.; Isen, Alice M.; Mancuso, Carol A.; Allegrante, John P.; Boutin-Foster, Carla; Ogedegbe, Gbenga; Jobe, Jared B.

    2013-01-01

    Objective: To describe a mixed-methods approach to develop and test a basic behavioral science-informed intervention to motivate behavior change in 3 high-risk clinical populations. Our theoretically derived intervention comprised a combination of positive affect and self-affirmation (PA/SA), which we applied to 3 clinical chronic disease…

  2. Financing Basic Education in Bangladesh. CREATE Pathways to Access. Research Monograph No. 12

    Science.gov (United States)

    Al-Samarrai, Samer

    2007-01-01

    This paper presents education finance trends for Bangladesh since 2000. It shows that while government spending on education as a proportion of national income has stagnated, it has increased in real terms. Real increases in education spending have resulted in substantial increases in per student spending in basic education. At primary, enrolment…

  3. DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor. (research article)

    NARCIS (Netherlands)

    L. Schaeffer; R. Roy (Richard); S. Humbert; V. Moncollin; W. Vermeulen (Wim); J.H.J. Hoeijmakers (Jan); P. Chambon; J-M. Egly (Jean-Marc)

    1993-01-01

    textabstractThe human BTF2 basic transcription factor (also called TFIIH), which is similar to the delta factor in rat and factor b in yeast, is required for class II gene transcription. A strand displacement assay was used to show that highly purified preparation of BTF2 had an adenosine

  4. Differences in citation frequency of clinical and basic science papers in cardiovascular research

    NARCIS (Netherlands)

    Opthof, T.

    2011-01-01

    In this article, a critical analysis is performed on differences in citation frequency of basic and clinical cardiovascular papers. It appears that the latter papers are cited at about 40% higher frequency. The differences between the largest number of citations of the most cited papers are even

  5. Differences in citation frequency of clinical and basic science papers in cardiovascular research

    NARCIS (Netherlands)

    Opthof, Tobias

    In this article, a critical analysis is performed on differences in citation frequency of basic and clinical cardiovascular papers. It appears that the latter papers are cited at about 40% higher frequency. The differences between the largest number of citations of the most cited papers are even

  6. Basic research in support of innovative fuels design for the Generation IV systems (F-BRIDGE project)

    International Nuclear Information System (INIS)

    Valot, Carole; Bertolus, Marjorie; Konings, Rudy; Somers, Joe; Groot, Sander de

    2010-01-01

    F-BRIDGE (Basic Research in support of Innovative Fuels Design for the GEN IV systems) is a 4-year project which started in 2008. It seeks to bridge the gap between basic research and technological applications for generation IV nuclear reactor systems. One of the challenges for the next generation of reactors is to significantly increase the efficiency in designing innovative fuels. The object of the F-BRIDGE project is to complement the empirical approach by a physically-based description of fuel and cladding materials to enable a rationalization of the design process and a better selection of promising fuel systems. Advanced modelling and separate effects experiments are carried out in order to obtain more exact physical descriptions of ceramic fuels and cladding, at relevant scales from the atomic to the macroscopic scale. Research is also focused on assessing and improving 'sphere-pac' fuel, a composite-ceramics concept which has shown promise. The project activities can be broken down into four main areas: (i) Basic research investigations using a multi-scale approach in both experimentation and modelling to enable the generation of missing basic data, the identification of relevant mechanisms and the development of appropriate models; (ii) Transfer between technological issues and basic research by bringing together within the same project materials scientists, engineers and end-users; (iii) Assessment of the drawbacks and benefits of the sphere-pac fuel application to various Generation IV systems; (iv) Education and training to promote research in the field of fuel materials, to ensure the exchange of results and ideas among the participants and to link the project with other related European or international initiatives. The project relies on the complementary expertise of 19 partners: nuclear and non nuclear research organisations, universities, a nuclear engineering company, as well as technology and project management consultancy small and medium

  7. Survey of basic data on human resources development (HRD) in the nuclear field in FNCA countries (Contract research)

    International Nuclear Information System (INIS)

    2005-03-01

    In the 3rd FNCA* (Forum for Nuclear Cooperation in Asia) Coordinator Meeting held on March 2002, it was proposed to carry out 'Survey of the Basic Data on Human Resources Development in the Nuclear Field'. It was considered to be the first step for developing the HRD strategy by producing the quantitative data on HRD in nuclear field. The survey results were introduced by Project Leaders during the 2002 FNCA Workshop on HRD held on October 2002. The follow-up survey was conducted with the cooperation of other Project Leaders in the respective field of FNCA such as medical and agriculture applications in each member countries. The collected survey data was analyzed in 2003, and summarized as 'Summary of the Survey Data'. This report consists of the summary of 'Survey of the Basic Data on Human Resources Development in Nuclear Field'. It was reported during the 2003 FNCA Workshop on HRD held on October 2003 and updated until early 2004. (author)

  8. Basic Research Needs for Solar Energy Utilization. Report of the Basic Energy Sciences Workshop on Solar Energy Utilization, April 18-21, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, N. S.; Crabtree, G.; Nozik, A. J.; Wasielewski, M. R.; Alivisatos, P.; Kung, H.; Tsao, J.; Chandler, E.; Walukiewicz, W.; Spitler, M.; Ellingson, R.; Overend, R.; Mazer, J.; Gress, M.; Horwitz, J.; Ashton, C.; Herndon, B.; Shapard, L.; Nault, R. M.

    2005-04-21

    World demand for energy is projected to more than double by 2050 and to more than triple by the end of the century. Incremental improvements in existing energy networks will not be adequate to supply this demand in a sustainable way. Finding sufficient supplies of clean energy for the future is one of society?s most daunting challenges. Sunlight provides by far the largest of all carbon-neutral energy sources. More energy from sunlight strikes the Earth in one hour (4.3 ? 1020 J) than all the energy consumed on the planet in a year (4.1 ? 1020 J). We currently exploit this solar resource through solar electricity ? a $7.5 billion industry growing at a rate of 35?40% per annum ? and solar-derived fuel from biomass, which provides the primary energy source for over a billion people. Yet, in 2001, solar electricity provided less than 0.1% of the world's electricity, and solar fuel from modern (sustainable) biomass provided less than 1.5% of the world's energy. The huge gap between our present use of solar energy and its enormous undeveloped potential defines a grand challenge in energy research. Sunlight is a compelling solution to our need for clean, abundant sources of energy in the future. It is readily available, secure from geopolitical tension, and poses no threat to our environment through pollution or to our climate through greenhouse gases. This report of the Basic Energy Sciences Workshop on Solar Energy Utilization identifies the key scientific challenges and research directions that will enable efficient and economic use of the solar resource to provide a significant fraction of global primary energy by the mid 21st century. The report reflects the collective output of the workshop attendees, which included 200 scientists representing academia, national laboratories, and industry in the United States and abroad, and the U.S. Department of Energy?s Office of Basic Energy Sciences and Office of Energy Efficiency and Renewable Energy.

  9. Is translational research compatible with preclinical publication strategies?

    International Nuclear Information System (INIS)

    Linder, Stig; Shoshan, Maria C

    2006-01-01

    The term 'translational research' is used to describe the transfer of basic biological knowledge into practical medicine, a process necessary for motivation of public spending. In the area of cancer therapeutics, it is becoming increasingly evident that results obtained in vitro and in animal models are difficult to translate into clinical medicine. We here argue that a number of factors contribute to making the translation process inefficient. These factors include the use of sensitive cell lines and fast growing experimental tumors as targets for novel therapies, and the use of unrealistic drug concentrations and radiation doses. We also argue that aggressive interpretation of data, successful in hypothesis-building biological research, does not form a solid base for development of clinically useful treatment modalities. We question whether 'clean' results obtained in simplified models, expected for publication in high-impact journals, represent solid foundations for improved treatment of patients. Open-access journals such as Radiation Oncology have a large mission to fulfill by publishing relevant data to be used for making actual progress in translational cancer research

  10. Cumulative abstracts of Cryogenic Technology Section proceedings of the Meeting on Engineering and Technology in Basic Research 1982-2003

    International Nuclear Information System (INIS)

    Ikeda, Hiroshi

    2005-01-01

    The Cryogenic Technology Section in the Meeting on Engineering and Technology in Basic Research had been held by Institute of Molecular Science, Plasma Research Center and KEK since 1976. The abstracts of papers and reports read in the meeting on engineering and technology in basic research from 1982 to 2003 are classified by five parts. The first part includes 22 papers on automation system; the second part contains 17 papers on cryostat production; the third part 31 papers on peripheral device; the forth 23 papers on production of cryogenic device and the fifth 18 papers on repair and management of cryogenic device. Further information is able to be obtained by each homepage. (S.Y.)

  11. Strategy for Promoting the Equitable Development of Basic Education in Underdeveloped Counties as Seen from Cili County

    Science.gov (United States)

    Shihua, Peng; Rihui, Tan

    2009-01-01

    Employing statistical analysis, this study has made a preliminary exploration of promoting the equitable development of basic education in underdeveloped counties through the case study of Cili county. The unequally developed basic education in the county has been made clear, the reasons for the inequitable education have been analyzed, and,…

  12. Research on the compressive strength of basic magnesium salts and cyanide slag solidified body

    Science.gov (United States)

    Tu, Yubo; Han, Peiwei; Ye, Shufeng; Wei, Lianqi; Zhang, Xiaomeng; Fu, Guoyan; Yu, Bo

    2018-02-01

    The solidification of cyanide slag by using basic magnesium salts could reduce pollution and protect the environment. Experiments were carried out to investigate the effects of age, mixing amount of cyanide slag, water cement ratio and molar ratio of MgO to MgSO4 on the compressive strength of basic magnesium salts and cyanide slag solidified body in the present paper. It was found that compressive strength of solidified body increased with the increase of age, and decreased with the increase of mixing amount of cyanide slag and water cement ratio. The molar ratio of MgO to MgSO4 should be controlled in the range from 9 to 11 when the mixing amount of cyanide slag was larger than 80 mass%.

  13. Hegemonic structure of basic, clinical and patented knowledge on Ebola research: a US army reductionist initiative

    OpenAIRE

    Fajardo-Ortiz, David; Ortega-S?nchez-de-Tagle, Jos?; Casta?o, Victor M

    2015-01-01

    Background Ebola hemorrhagic fever (Ebola) is still a highly lethal infectious disease long affecting mainly neglected populations in sub-Saharan Africa. Moreover, this disease is now considered a potential worldwide threat. In this paper, we present an approach to understand how the basic, clinical and patent knowledge on Ebola is organized and intercommunicated and what leading factor could be shaping the evolution of the knowledge translation process for this disease. Methodology A combina...

  14. Radioisotope Production Plan and Strategy of Kijang Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kye Hong; Lee, Jun Sig [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    This reactor will be located at Kijang, Busan, Korea and be dedicated to produce mainly medical radioisotopes. Tc-99m is very important isotope for diagnosis and more than 80% of radiation diagnostic procedures in nuclear medicine depend on this isotope. There were, however, several times of insecure production of Mo-99 due to the shutdown of major production reactors worldwide. OECD/NEA is leading member countries to resolve the shortage of this isotope and trying to secure the international market of Mo-99. The radioisotope plan and strategy of Kijang Research Reactor (KJRR) should be carefully established to fit not only the domestic but also international demand on Mo-99. The implementation strategy of 6 principles of HLG-MR should be established that is appropriate to national environments. Ministry of Science, ICT and Future Planning and Ministry of Health and welfare should cooperate well to organize the national radioisotope supply structure, to set up the reasonable and competitive pricing of radioisotopes, and to cope with the international supply strategy.

  15. The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis.

    Science.gov (United States)

    Heijman, Jordi; Algalarrondo, Vincent; Voigt, Niels; Melka, Jonathan; Wehrens, Xander H T; Dobrev, Dobromir; Nattel, Stanley

    2016-04-01

    Atrial fibrillation (AF) is an extremely common clinical problem associated with increased morbidity and mortality. Current antiarrhythmic options include pharmacological, ablation, and surgical therapies, and have significantly improved clinical outcomes. However, their efficacy remains suboptimal, and their use is limited by a variety of potentially serious adverse effects. There is a clear need for improved therapeutic options. Several decades of research have substantially expanded our understanding of the basic mechanisms of AF. Ectopic firing and re-entrant activity have been identified as the predominant mechanisms for arrhythmia initiation and maintenance. However, it has become clear that the clinical factors predisposing to AF and the cellular and molecular mechanisms involved are extremely complex. Moreover, all AF-promoting and maintaining mechanisms are dynamically regulated and subject to remodelling caused by both AF and cardiovascular disease. Accordingly, the initial presentation and clinical progression of AF patients are enormously heterogeneous. An understanding of arrhythmia mechanisms is widely assumed to be the basis of therapeutic innovation, but while this assumption seems self-evident, we are not aware of any papers that have critically examined the practical contributions of basic research into AF mechanisms to arrhythmia management. Here, we review recent insights into the basic mechanisms of AF, critically analyse the role of basic research insights in the development of presently used anti-AF therapeutic options and assess the potential value of contemporary experimental discoveries for future therapeutic innovation. Finally, we highlight some of the important challenges to the translation of basic science findings to clinical application. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: journals.permissions@oup.com.

  16. Ecosystem approach to inland fisheries: research needs and implementation strategies

    Science.gov (United States)

    Beard, T. Douglas; Arlinghaus, Robert; Cooke, Steven J.; McIntyre, Peter B.; De Silva, Sena; Bartley, Devin M.; Cowx, Ian G.

    2011-01-01

    Inland fisheries are a vital component in the livelihoods and food security of people throughout the world, as well as contributing huge recreational and economic benefits. These valuable assets are jeopardized by lack of research-based understanding of the impacts of fisheries on inland ecosystems, and similarly the impact of human activities associated with inland waters on fisheries and aquatic biodiversity. To explore this topic, an international workshop was organized in order to examine strategies to incorporate fisheries into ecosystem approaches for management of inland waters. To achieve this goal, a new research agenda is needed that focuses on: quantifying the ecosystem services provided by fresh waters; quantifying the economic, social and nutritional benefits of inland fisheries; improving assessments designed to evaluate fisheries exploitation potential; and examining feedbacks between fisheries, ecosystem productivity and aquatic biodiversity. Accomplishing these objectives will require merging natural and social science approaches to address coupled social–ecological system dynamics.

  17. Stem Cell Basics

    Science.gov (United States)

    ... Tips Info Center Research Topics Federal Policy Glossary Stem Cell Information General Information Clinical Trials Funding Information Current ... Basics » Stem Cell Basics I. Back to top Stem Cell Basics I. Introduction: What are stem cells, and ...

  18. Research Skills for Journalism Students: From Basics to Computer-Assisted Reporting.

    Science.gov (United States)

    Drueke, Jeanetta; Streckfuss, Richard

    1997-01-01

    Despite the availability of computer-assisted research, a survey of 300 newspapers found that many journalists still rely on paper sources or neglect research altogether. This article describes the development and implementation of a beginning reporting course that integrates research skills, demonstrates the value of research in reporting, and…

  19. ARM Climate Research Facility: Outreach Tools and Strategies

    Science.gov (United States)

    Roeder, L.; Jundt, R.

    2009-12-01

    Sponsored by the Department of Energy, the ARM Climate Research Facility is a global scientific user facility for the study of climate change. To publicize progress and achievements and to reach new users, the ACRF uses a variety of Web 2.0 tools and strategies that build off of the program’s comprehensive and well established News Center (www.arm.gov/news). These strategies include: an RSS subscription service for specific news categories; an email “newsletter” distribution to the user community that compiles the latest News Center updates into a short summary with links; and a Facebook page that pulls information from the News Center and links to relevant information in other online venues, including those of our collaborators. The ACRF also interacts with users through field campaign blogs, like Discovery Channel’s EarthLive, to share research experiences from the field. Increasingly, field campaign Wikis are established to help ACRF researchers collaborate during the planning and implementation phases of their field studies and include easy to use logs and image libraries to help record the campaigns. This vital reference information is used in developing outreach material that is shared in highlights, news, and Facebook. Other Web 2.0 tools that ACRF uses include Google Maps to help users visualize facility locations and aircraft flight patterns. Easy-to-use comment boxes are also available on many of the data-related web pages on www.arm.gov to encourage feedback. To provide additional opportunities for increased interaction with the public and user community, future Web 2.0 plans under consideration for ACRF include: evaluating field campaigns for Twitter and microblogging opportunities, adding public discussion forums to research highlight web pages, moving existing photos into albums on FlickR or Facebook, and building online video archives through YouTube.

  20. Terrestrial ecosystem responses to global change: A research strategy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    Uncertainty about the magnitude of global change effects on terrestrial ecosystems and consequent feedbacks to the atmosphere impedes sound policy planning at regional, national, and global scales. A strategy to reduce these uncertainties must include a substantial increase in funding for large-scale ecosystem experiments and a careful prioritization of research efforts. Prioritization criteria should be based on the magnitude of potential changes in environmental properties of concern to society, including productivity; biodiversity; the storage and cycling of carbon, water, and nutrients; and sensitivity of specific ecosystems to environmental change. A research strategy is proposed that builds on existing knowledge of ecosystem responses to global change by (1) expanding the spatial and temporal scale of experimental ecosystem manipulations to include processes known to occur at large scales and over long time periods; (2) quantifying poorly understood linkages among processes through the use of experiments that manipulate multiple interacting environmental factors over a broader range of relevant conditions than did past experiments; and (3) prioritizing ecosystems for major experimental manipulations on the basis of potential positive and negative impacts on ecosystem properties and processes of intrinsic and/or utilitarian value to humans and on feedbacks of terrestrial ecosystems to the atmosphere.

  1. Human Pathogens on Plants: Designing a Multidisciplinary Strategy for Research.

    Science.gov (United States)

    Fletcher, Jacqueline; Leach, Jan E; Eversole, Kellye; Tauxe, Robert

    2014-10-15

    Recent efforts to address concerns about microbial contamination of food plants and resulting foodborne illness have prompted new collaboration and interactions between the scientific communities of plant pathology and food safety. This article provides perspectives from scientists of both disciplines and presents selected research results and concepts that highlight existing and possible future synergisms for audiences of both disciplines. Plant pathology is a complex discipline that encompasses studies of the dissemination, colonization, and infection of plants by microbes such as bacteria, viruses, fungi, and oomycetes. Plant pathologists study plant diseases as well as host plant defense responses and disease management strategies with the goal of minimizing disease occurrences and impacts. Repeated outbreaks of human illness attributed to the contamination of fresh produce, nuts and seeds, and other plant-derived foods by human enteric pathogens such as Shiga toxin-producing Escherichia coli and Salmonella spp. have led some plant pathologists to broaden the application of their science in the past two decades, to address problems of human pathogens on plants (HPOPs). Food microbiology, which began with the study of microbes that spoil foods and those that are critical to produce food, now also focuses study on how foods become contaminated with pathogens and how this can be controlled or prevented. Thus, at the same time, public health researchers and food microbiologists have become more concerned about plant-microbe interactions before and after harvest. New collaborations are forming between members of the plant pathology and food safety communities, leading to enhanced research capacity and greater understanding of the issues for which research is needed. The two communities use somewhat different vocabularies and conceptual models. For example, traditional plant pathology concepts such as the disease triangle and the disease cycle can help to define

  2. Human pathogens on plants: designing a multidisciplinary strategy for research.

    Science.gov (United States)

    Fletcher, Jacqueline; Leach, Jan E; Eversole, Kellye; Tauxe, Robert

    2013-04-01

    Recent efforts to address concerns about microbial contamination of food plants and resulting foodborne illness have prompted new collaboration and interactions between the scientific communities of plant pathology and food safety. This article provides perspectives from scientists of both disciplines and presents selected research results and concepts that highlight existing and possible future synergisms for audiences of both disciplines. Plant pathology is a complex discipline that encompasses studies of the dissemination, colonization, and infection of plants by microbes such as bacteria, viruses, fungi, and oomycetes. Plant pathologists study plant diseases as well as host plant defense responses and disease management strategies with the goal of minimizing disease occurrences and impacts. Repeated outbreaks of human illness attributed to the contamination of fresh produce, nuts and seeds, and other plant-derived foods by human enteric pathogens such as Shiga toxin-producing Escherichia coli and Salmonella spp. have led some plant pathologists to broaden the application of their science in the past two decades, to address problems of human pathogens on plants (HPOPs). Food microbiology, which began with the study of microbes that spoil foods and those that are critical to produce food, now also focuses study on how foods become contaminated with pathogens and how this can be controlled or prevented. Thus, at the same time, public health researchers and food microbiologists have become more concerned about plant-microbe interactions before and after harvest. New collaborations are forming between members of the plant pathology and food safety communities, leading to enhanced research capacity and greater understanding of the issues for which research is needed. The two communities use somewhat different vocabularies and conceptual models. For example, traditional plant pathology concepts such as the disease triangle and the disease cycle can help to define

  3. Utilization of Compliance-Gaining Strategies: A Research Note.

    Science.gov (United States)

    Baglan, Thomas; And Others

    1986-01-01

    Examined the use of compliance-gaining strategies among a group of environmentalists. Results indicated that prosocial strategies were used more often than anti-social strategies across all situations. (SRT)

  4. Basic research for nuclear energy. y Study on the nuclear materials technology

    Energy Technology Data Exchange (ETDEWEB)

    Kuk, I H; Lee, H S; Jeong, Y H; Sung, K W; Han, J H; Lee, J T; Lee, H K; Kim, S J; Kang, H S; An, D H; Kim, K R; Park, S D; Han, C H; Jung, M K; Oh, Y J; Kim, K H; Kim, S H; Back, J H; Kim, C H; Lim, K S; Kim, Y Y; Na, J W; Ku, J H; Lee, D H

    1996-12-01

    A study on the nuclear materials technologies which are necessary to establish the base for alloy development was performed. - The feasibility study on the application of Zircaloy scrap waste for hydrogen storage - The development of metal hydride battery for energy storage system - The establishment of transmission electron microscopy database for nuclear materials - The basic technology for the development of cladding materials for high burnup - The water chemistry technology for secondary system pH control and the photocatalysis technology for decomposition and removal of organics. - Improvement of primary component integrity of PWR by Zinc injection. (author). 175 refs., 58 tabs., 262 figs.

  5. Research on the Architecture of a Basic Reconfigurable Information Communication Network

    Directory of Open Access Journals (Sweden)

    Ruimin Wang

    2013-01-01

    Full Text Available The current information network cannot fundamentally meet some urgent requirements, such as providing ubiquitous information services and various types of heterogeneous network, supporting diverse and comprehensive network services, possessing high quality communication effects, ensuring the security and credibility of information interaction, and implementing effective supervisory control. This paper provides the theory system for the basic reconfigurable information communication network based on the analysis of present problems on the Internet and summarizes the root of these problems. It also provides an in-depth discussion about the related technologies and the prime components of the architecture.

  6. Indicators for the use of robotic labs in basic biomedical research: a literature analysis

    Directory of Open Access Journals (Sweden)

    Paul Groth

    2017-11-01

    Full Text Available Robotic labs, in which experiments are carried out entirely by robots, have the potential to provide a reproducible and transparent foundation for performing basic biomedical laboratory experiments. In this article, we investigate whether these labs could be applicable in current experimental practice. We do this by text mining 1,628 papers for occurrences of methods that are supported by commercial robotic labs. Using two different concept recognition tools, we find that 86%–89% of the papers have at least one of these methods. This and our other results provide indications that robotic labs can serve as the foundation for performing many lab-based experiments.

  7. Basic research for nuclear energy. y Study on the nuclear materials technology

    International Nuclear Information System (INIS)

    Kuk, I. H.; Lee, H. S.; Jeong, Y. H.; Sung, K. W.; Han, J. H.; Lee, J. T.; Lee, H. K.; Kim, S. J.; Kang, H. S.; An, D. H.; Kim, K. R.; Park, S. D.; Han, C. H.; Jung, M. K.; Oh, Y. J.; Kim, K. H.; Kim, S. H.; Back, J. H.; Kim, C. H.; Lim, K. S.; Kim, Y. Y.; Na, J. W.; Ku, J. H.; Lee, D. H.

    1996-12-01

    A study on the nuclear materials technologies which are necessary to establish the base for alloy development was performed. - The feasibility study on the application of Zircaloy scrap waste for hydrogen storage - The development of metal hydride battery for energy storage system - The establishment of transmission electron microscopy database for nuclear materials - The basic technology for the development of cladding materials for high burnup - The water chemistry technology for secondary system pH control and the photocatalysis technology for decomposition and removal of organics. - Improvement of primary component integrity of PWR by Zinc injection. (author). 175 refs., 58 tabs., 262 figs

  8. A model for integrating clinical care and basic science research, and pitfalls of performing complex research projects for addressing a clinical challenge.

    Science.gov (United States)

    Steck, R; Epari, D R; Schuetz, M A

    2010-07-01

    The collaboration of clinicians with basic science researchers is crucial for addressing clinically relevant research questions. In order to initiate such mutually beneficial relationships, we propose a model where early career clinicians spend a designated time embedded in established basic science research groups, in order to pursue a postgraduate qualification. During this time, clinicians become integral members of the research team, fostering long term relationships and opening up opportunities for continuing collaboration. However, for these collaborations to be successful there are pitfalls to be avoided. Limited time and funding can lead to attempts to answer clinical challenges with highly complex research projects characterised by a large number of "clinical" factors being introduced in the hope that the research outcomes will be more clinically relevant. As a result, the complexity of such studies and variability of its outcomes may lead to difficulties in drawing scientifically justified and clinically useful conclusions. Consequently, we stress that it is the basic science researcher and the clinician's obligation to be mindful of the limitations and challenges of such multi-factorial research projects. A systematic step-by-step approach to address clinical research questions with limited, but highly targeted and well defined research projects provides the solid foundation which may lead to the development of a longer term research program for addressing more challenging clinical problems. Ultimately, we believe that it is such models, encouraging the vital collaboration between clinicians and researchers for the work on targeted, well defined research projects, which will result in answers to the important clinical challenges of today. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  9. New visions for basic research and primary prevention of pediatric allergy

    DEFF Research Database (Denmark)

    Hamelman, E.; Herz, U.; Holt, P.

    2008-01-01

    , resources need to be focused on better understanding of the early allergic events and on interventional studies to investigate new strategies of primary and secondary prevention. Accordingly, this review summarizes the state-of-the-art of genetic, immunological and clinical aspects of primary prevention...

  10. Translational research strategy: an essential approach to fight the spread of antimicrobial resistance.

    Science.gov (United States)

    Tacconelli, Evelina; Peschel, Andreas; Autenrieth, Ingo B

    2014-11-01

    Translation research strategy in infectious diseases, combining the results from basic research with patient-orientated research, aims to bridge the gap between laboratory findings and clinical infectious disease practice to improve disease management. In an era of increasing antimicrobial resistance, there are four main areas of clinical and scientific uncertainty that need to be urgently addressed by translational research: (i) early diagnosis of antibiotic-resistant infections and the appropriateness of empirical antibiotic therapy; (ii) the identification of reservoirs of antibiotic-resistant pathogens; (iii) the development of new antibiotics with lower propensities to evoke resistance; and (iv) the development of new non-antibiotic drugs to be used in the prevention of the spread of resistant bacterial strains. Strict European collaboration among major stakeholders is therefore essential. Appropriate educational tools to train a new generation of scientists with regard to a multifaceted approach to antimicrobial resistance research should be developed. Key areas include the support and implementation of European networks focused on translational research and related education activities, making potential therapeutics more attractive to investors and helping academic investigators to determine whether new molecules can be developed with clinical applicability. © The Author 2014. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  11. Life Strategies of Young People: Sociological Research Experience

    Directory of Open Access Journals (Sweden)

    Lyubov’ Borisovna Osipova

    2016-09-01

    Full Text Available Modern reality is the world of formation of various life prospects of a young person. The relevance of the topic depends, firstly, on insufficient sociological research into the mechanism of formation and realization of life strategies of modern youth; and, secondly, on the need to substantiate the sociological concept of youth life strategies in terms of professional self-determination with regard to its social and group characteristics. In this context, young people as the most active social group are of great interest to the authors who consider them a research target. Due to the transitivity of a social status and the incomplete processes of social maturity formation young people need a targeted design of their future. The sociological analysis of the issue involves a clarification of the concept of “life strategy” at the conceptual level (A.A. Volokitin, S.N. Ikonnikova, E.I. Golovakha, Yu.A. Zubok, V.T. Lisovsky, M.N. Rutkevich, G.V. Leonidova, K.A. Ustinova, etc.. The article presents the author’s definition of “life strategies”, which is a dynamic system of perspective individual orientation aimed at designing one’s life in the future. At the same time the results of the author’s sociological research are presented, including a standardized interview, questionnaires, which provide an opportunity to form an idea about the living choices of young people living in Yugra. The declining influence of social institutions and the emerging opportunities for developing their life prospects on their own challenges young people to select their life targets and ways of their implementation independently. The article justifies the necessity of intensified activation of new forms of young students’ management when planning their life trajectory. Life strategies disclose its content in specific life situations associated with choice. The key choice is the career choice of young people which directly depends on the socio

  12. Energy in Ireland: context, strategy and research; Energie en Irlande: contexte, strategie et recherche

    Energy Technology Data Exchange (ETDEWEB)

    Saintherant, N.; Lerouge, Ch.; Welcker, A

    2008-01-15

    In the present day situation of sudden awareness about climatic change and announced fossil fuels shortage, Ireland has defined a new strategy for its energy future. Context: Ireland is strongly dependent of oil and gas imports which increase regularly to meet the demand. A small part of the electricity consumed is imported from Ulster. The share of renewable energies remains weak but is increasing significantly. Therefore, from 1990 to 2006, the proportion of renewable energies increased from 1.9% (mainly of hydroelectric origin) to 4.5%. Wind power represents now the main renewable energy source. The transportation sector is the most energy consuming and the biggest source of greenhouse gases. Strategy: the Irish policy is driven by pluri-annual strategic plans which define the objectives and means. Priority is given to the security of supplies at affordable prices: 8.5 billion euros will be invested during the 2007-2013 era for the modernization of existing energy infrastructures and companies, and in a lesser extent for the development of renewable energy sources. During this period, 415 million euros more will be devoted to the research, development and demonstration (RD and D) of new energy solutions. Research: in 2005 the energy RD and D expenses reached 12.8 million euros shared between 54% for R and D and 46% for demonstration projects. Half of the financing is given to higher education schools and is devoted to energy saving purposes (33%) and to renewable energies (29%, mainly wind power and biomass). Academic research gives a particular attention to ocean energy which represents an important potential resource in Ireland and which has already led to the creation of innovative companies. The integration of renewable energy sources to the power grid and the stability of supplies are also the object of active researches. (J.S.)

  13. Strategies for involving undergraduates in mentored research (Invited)

    Science.gov (United States)

    Marin-Spiotta, E.

    2013-12-01

    Early engagement in research can transform the undergraduate experience and has a positive effect on minority student recruitment to graduate school. Multiple strategies used to involve undergraduates in research at a large R1 university are presented. During my first four years as an assistant professor, my lab has hosted 14 undergraduates, 9 of them women and 4 of them Hispanic. Institutional support has been critical for undergraduate student involvement. UW supports a research program for incoming underrepresented students. An advantage of this program is very early research participation, with the opportunity for long-term training. One disadvantage is that many first year students have not yet identified their interests. The Biology major also requires students to complete an independent project, which culminates in a research symposium. Competitive research fellowships and grants are available for students to conduct work under faculty mentorship. We have been successful at keeping students on even when their majors are very different from our research discipline, mainly by providing flexibility and a welcoming lab environment. This mentoring culture is strongly fostered by graduate student interest and involvement with all undergraduates as well as active mentor training. By offering multiple pathways for involvement, we can accommodate students' changing schedules and priorities as well as changing lab needs. Students can volunteer, receive course credit, conduct an independent project or honors thesis, contribute to an existing project, do lab work or write a literature review, work with one mentor or on multiple projects. We often provide employment over the summer and subsequent semesters for continuing students. Some will increase their commitment over time and work more closely with me. Others reduce down to a few hours a week as they gain experience elsewhere. Most students stay multiple semesters and multiple years because they 'enjoy being in the

  14. NATO Advanced Study Institute on Nano-Optics : Principles Enabling Basic Research and Applications

    CERN Document Server

    Collins, John; Silvestri, Luciano

    2017-01-01

    This book provides a comprehensive overview of nano-optics, including basic theory, experiment and applications, particularly in nanofabrication and optical characterization. The contributions clearly demonstrate how advances in nano-optics and photonics have stimulated progress in nanoscience and -fabrication, and vice versa. Their expert authors address topics such as three-dimensional optical lithography and microscopy beyond the Abbe diffraction limit, optical diagnostics and sensing, optical data- and telecommunications, energy-efficient lighting, and efficient solar energy conversion. Nano-optics emerges as a key enabling technology of the 21st century. This work will appeal to a wide readership, from physics through chemistry, to biology and engineering. The contributions that appear in this volume were presented at a NATO Advanced Study Institute held in Erice, 4-19 July, 2015.

  15. Without continuous basic research technology will stagnate and economy will be in no growth. Why?

    DEFF Research Database (Denmark)

    Pedersen, Jørgen Lindgaard

    2008-01-01

    The paper presents some ideas about new knowledge and the effects from knowledge on development of new technology. Paul M. Romer established in the 1980s the so-called New Growth Economy. The basic idea is here that knowledge is included explicitly in the production function. With knowledge...... as a public good its unit costs will be declining and it can substitute other inputs with not-declining unit costs. A problem with that idea is the neglect of the cost connected with production of a new idea. Joel Mokyr has from the end of 1990s developed his ideas about the knowledge economy. He distingues...... between propositional knowledge and prescriptive knowledge. The first-mentioned is about what nature is. The second-mentioned is about how to manipulate to get a wanted result. What is important is that m ost important new technologies cannot be developed without many different areas of propositional...

  16. Basic considerations for the safety analysis report of the Greek Research Reactor-1 (GRR-1)

    International Nuclear Information System (INIS)

    Anoussis, J.N.; Chrysochoides, N.G.; Papastergiou, C.N.

    1980-09-01

    The basic considerations upon which the new revised Safety Analysis Report (SAR) for the GRR-1 will be based are presented. The format and the content the SAR will follow are given. A number of credible and less credible accidents is briefly analysed on the basis of present knowledge and experience for similar reactors, as well as the experience gained in the last 10 years of the GRR-1 operation at 5 MW. The accident caused by partial blockage of the cooling flow is considered to be the Maximum Credible Accident (MCA) for the GRR-1. The MCA is analysed and its radiological impact to the environment is estimated using conservative assumptions. (T.A.)

  17. Regenerative dentistry: translating advancements in basic science research to the dental practice.

    Science.gov (United States)

    Garcia-Godoy, Franklin; Murray, Peter

    2010-01-01

    Scientific advances in the creation of restorative biomaterials, in vitro cell culture technology, tissue engineering, molecular biology and the human genome project provide the basis for the introduction of new technologies into dentistry. This review provides an assessment of how tissue engineering, stem cell, genetic transfer, biomaterial and growth factor therapies can be integrated into clinical dental therapies to restore and regenerate oral tissues. In parallel to the creation of a new field in general medicine called "regenerative medicine," we call this field "regenerative dentistry." While the problems of introducing regenerative therapies are substantial, the potential benefits to patients and the profession are equally ground-breaking. In this review, we outline a few areas of interest for the future of oral and dental medicine in which advancements in basic science have already been adapted to fit the goals of 21st century dentistry.

  18. Researcher Mobility at a US Research-Intensive University: Implications for Research and Internationalization Strategies

    Science.gov (United States)

    Payumo, Jane G.; Lan, George; Arasu, Prema

    2018-01-01

    This study offers a unique lens on the patterns, productivity, and impact of researcher mobility at a US research-intensive university. Bibliometric data for Washington State University (WSU) was extracted from Elsevier's Scopus database and analyzed for the 10-year period from 2002 to 2012. We grouped researchers into four categories based on…

  19. Curating research data practical strategies for your digital repository

    CERN Document Server

    Johnston, Lisa R

    2017-01-01

    Volume One of Curating Research Data explores the variety of reasons, motivations, and drivers for why data curation services are needed in the context of academic and disciplinary data repository efforts. Twelve chapters, divided into three parts, take an in-depth look at the complex practice of data curation as it emerges around us. Part I sets the stage for data curation by describing current policies, data sharing cultures, and collaborative efforts currently underway that impact potential services. Part II brings several key issues, such as cost recovery and marketing strategy, into focus for practitioners when considering how to put data curation services in action. Finally, Part III describes the full lifecycle of data by examining the ethical and practical reuse issues that data curation practitioners must consider as we strive to prepare data for the future.

  20. Brushless DC motor speed control strategy of simulation research

    Directory of Open Access Journals (Sweden)

    Xiang Wen

    2017-01-01

    Full Text Available In view of the brushless DC motor speed regulation problem, an ideal control strategy is designed. Through the model and analysis of Brushless DC motor, the mathematical model of the brushless DC motor is obtained. By comparing three control strategies of PID control strategy, fuzzy control strategy and fuzzy PID control strategy, PID controller, fuzzy controller and fuzzy PID controller are designed respectively for simulation test. The simulation results show that the fuzzy PID controller has good control effect.

  1. Translational toxicology: a developmental focus for integrated research strategies.

    Science.gov (United States)

    Hughes, Claude; Waters, Michael; Allen, David; Obasanjo, Iyabo

    2013-09-30

    Given that toxicology studies the potential adverse effects of environmental exposures on various forms of life and that clinical toxicology typically focuses on human health effects, what can and should the relatively new term of "translational toxicology" be taken to mean? Our assertion is that the core concept of translational toxicology must incorporate existing principles of toxicology and epidemiology, but be driven by the aim of developing safe and effective interventions beyond simple reduction or avoidance of exposure to prevent, mitigate or reverse adverse human health effects of exposures.The field of toxicology has now reached a point where advances in multiple areas of biomedical research and information technologies empower us to make fundamental transitions in directly impacting human health. Translational toxicology must encompass four action elements as follows: 1) Assessing human exposures in critical windows across the lifespan; 2) Defining modes of action and relevance of data from animal models; 3) Use of mathematical models to develop plausible predictions as the basis for: 4) Protective and restorative human health interventions. The discussion focuses on the critical window of in-utero development. Exposure assessment, basic toxicology and development of certain categories of mathematical models are not new areas of research; however overtly integrating these in order to conceive, assess and validate effective interventions to mitigate or reverse adverse effects of environmental exposures is our novel opportunity. This is what we should do in translational toxicology so that we have a portfolio of interventional options to improve human health that include both minimizing exposures and specific preventative/restorative/mitigative therapeutics.

  2. Bursaries, writing grants and fellowships: a strategy to develop research capacity in primary health care

    Directory of Open Access Journals (Sweden)

    Farmer Elizabeth A

    2007-04-01

    Full Text Available Abstract Background General practitioners and other primary health care professionals are often the first point of contact for patients requiring health care. Identifying, understanding and linking current evidence to best practice can be challenging and requires at least a basic understanding of research principles and methodologies. However, not all primary health care professionals are trained in research or have research experience. With the aim of enhancing research skills and developing a research culture in primary health care, University Departments of General Practice and Rural Health have been supported since 2000 by the Australian Government funded 'Primary Health Care Research Evaluation and Development (PHCRED Strategy'. A small grant funding scheme to support primary health care practitioners was implemented through the PHCRED program at Flinders University in South Australia between 2002 and 2005. The scheme incorporated academic mentors and three types of funding support: bursaries, writing grants and research fellowships. This article describes outcomes of the funding scheme and contributes to the debate surrounding the effectiveness of funding schemes as a means of building research capacity. Methods Funding recipients who had completed their research were invited to participate in a semi-structured 40-minute telephone interview. Feedback was sought on acquisition of research skills, publication outcomes, development of research capacity, confidence and interest in research, and perception of research. Data were also collected on demographics, research topics, and time needed to complete planned activities. Results The funding scheme supported 24 bursaries, 11 writing grants, and three research fellows. Nearly half (47% of all grant recipients were allied health professionals, followed by general practitioners (21%. The majority (70% were novice and early career researchers. Eighty-nine percent of the grant recipients were

  3. Survey of basic medical researchers on the awareness of animal experimental designs and reporting standards in China.

    Directory of Open Access Journals (Sweden)

    Bin Ma

    Full Text Available To investigate the awareness and use of the Systematic Review Center for Laboratory Animal Experimentation's (SYRCLE risk-of-bias tool, the Animal Research: Reporting of In Vivo Experiments (ARRIVE reporting guidelines, and Gold Standard Publication Checklist (GSPC in China in basic medical researchers of animal experimental studies.A national questionnaire-based survey targeting basic medical researchers was carried in China to investigate the basic information and awareness of SYRCLE's risk of bias tool, ARRIVE guidelines, GSPC, and animal experimental bias risk control factors. The EpiData3.1 software was used for data entry, and Microsoft Excel 2013 was used for statistical analysis in this study. The number of cases (n and percentage (% of classified information were statistically described, and the comparison between groups (i.e., current students vs. research staff was performed using chi-square test.A total of 298 questionnaires were distributed, and 272 responses were received, which included 266 valid questionnaires (from 118 current students and 148 research staff. Among the 266 survey participants, only 15.8% was aware of the SYRCLE's risk of bias tool, with significant difference between the two groups (P = 0.003, and the awareness rates of ARRIVE guidelines and GSPC were only 9.4% and 9.0%, respectively; 58.6% survey participants believed that the reports of animal experimental studies in Chinese literature were inadequate, with significant difference between the two groups (P = 0.004. In addition, only approximately 1/3 of the survey participants had read systematic reviews and meta-analysis reports of animal experimental studies; only 16/266 (6.0% had carried out/participated in and 11/266 (4.1% had published systematic reviews/meta-analysis of animal experimental studies.The awareness and use rates of SYRCLE's risk-of-bias tool, the ARRIVE guidelines, and the GSPC were low among Chinese basic medical researchers. Therefore

  4. Thinking science with thinking machines: The multiple realities of basic and applied knowledge in a research border zone.

    Science.gov (United States)

    Hoffman, Steve G

    2015-04-01

    Some scholars dismiss the distinction between basic and applied science as passé, yet substantive assumptions about this boundary remain obdurate in research policy, popular rhetoric, the sociology and philosophy of science, and, indeed, at the level of bench practice. In this article, I draw on a multiple ontology framework to provide a more stable affirmation of a constructivist position in science and technology studies that cannot be reduced to a matter of competing perspectives on a single reality. The analysis is grounded in ethnographic research in the border zone of Artificial Intelligence science. I translate in-situ moments in which members of neighboring but differently situated labs engage in three distinct repertoires that render the reality of basic and applied science: partitioning, flipping, and collapsing. While the essences of scientific objects are nowhere to be found, the boundary between basic and applied is neither illusion nor mere propaganda. Instead, distinctions among scientific knowledge are made real as a matter of course.

  5. Seventh BES [Basic Energy Sciences] catalysis and surface chemistry research conference

    International Nuclear Information System (INIS)

    1990-03-01

    Research programs on catalysis and surface chemistry are presented. A total of fifty-seven topics are included. Areas of research include heterogeneous catalysis; catalysis in hydrogenation, desulfurization, gasification, and redox reactions; studies of surface properties and surface active sites; catalyst supports; chemical activation, deactivation; selectivity, chemical preparation; molecular structure studies; sorption and dissociation. Individual projects are processed separately for the data bases

  6. An International Basic Science and Clinical Research Summer Program for Medical Students

    Science.gov (United States)

    Ramjiawan, Bram; Pierce, Grant N.; Anindo, Mohammad Iffat Kabir; AlKukhun, Abedalrazaq; Alshammari, Abdullah; Chamsi, Ahmad Talal; Abousaleh, Mohannad; Alkhani, Anas; Ganguly, Pallab K.

    2012-01-01

    An important part of training the next generation of physicians is ensuring that they are exposed to the integral role that research plays in improving medical treatment. However, medical students often do not have sufficient time to be trained to carry out any projects in biomedical and clinical research. Many medical students also fail to…

  7. Seventh BES (Basic Energy Sciences) catalysis and surface chemistry research conference

    Energy Technology Data Exchange (ETDEWEB)

    1990-03-01

    Research programs on catalysis and surface chemistry are presented. A total of fifty-seven topics are included. Areas of research include heterogeneous catalysis; catalysis in hydrogenation, desulfurization, gasification, and redox reactions; studies of surface properties and surface active sites; catalyst supports; chemical activation, deactivation; selectivity, chemical preparation; molecular structure studies; sorption and dissociation. Individual projects are processed separately for the data bases. (CBS)

  8. MaizeGDB: enabling access to basic, translational, and applied research information

    Science.gov (United States)

    MaizeGDB is the Maize Genetics and Genomics Database (available online at http://www.maizegdb.org). The MaizeGDB project is not simply an online database and website but rather an information service to maize researchers that supports customized data access and analysis needs to individual research...

  9. Research Strategy for Modeling the Complexities of Turbine Heat Transfer

    Science.gov (United States)

    Simoneau, Robert J.

    1996-01-01

    The subject of this paper is a NASA research program, known as the Coolant Flow Management Program, which focuses on the interaction between the internal coolant channel and the external film cooling of a turbine blade and/or vane in an aircraft gas turbine engine. The turbine gas path is really a very complex flow field. The combination of strong pressure gradients, abrupt geometry changes and intersecting surfaces, viscous forces, rotation, and unsteady blade/vane interactions all combine to offer a formidable challenge. To this, in the high pressure turbine, we add the necessity of film cooling. The ultimate goal of the turbine designer is to maintain or increase the high level of turbine performance and at the same time reduce the amount of coolant flow needed to achieve this end. Simply stated, coolant flow is a penalty on the cycle and reduces engine thermal efficiency. Accordingly, understanding the flow field and heat transfer associated with the coolant flow is a priority goal. It is important to understand both the film cooling and the internal coolant flow, particularly their interaction. Thus, the motivation for the Coolant Flow Management Program. The paper will begin with a brief discussion of the management and research strategy, will then proceed to discuss the current attack from the internal coolant side, and will conclude by looking at the film cooling effort - at all times keeping sight of the primary goal the interaction between the two. One of the themes of this paper is that complex heat transfer problems of this nature cannot be attacked by single researchers or even groups of researchers, each working alone. It truly needs the combined efforts of a well-coordinated team to make an impact. It is important to note that this is a government/industry/university team effort.

  10. Physician-based smoking intervention: a rededication to a five-step strategy to smoking research.

    Science.gov (United States)

    Ockene, J K; Zapka, J G

    1997-01-01

    It is well established that physicians can have a significant effect on the smoking behavior of their patients. To do this, attention must be paid to putting in place multiple strategies or mechanisms in the organization where the physician practices, as well as in the macroenvironment (i.e., social and public policy). It has been questioned whether or not there is stagnation in the field of clinical smoking intervention requiring a rededication to basic research regarding smoking. With respect to physician-based smoking intervention, we alternatively suggest that recommitment to all phases of research is essential for moving forward physician-based smoking interventions in the rapidly changing health services and social environment. In this article, we first review the essential framework of the National Cancer Institute's research science approach to cancer prevention and control. Evidence concerning physician-based interventions is then reviewed, followed by a schematic of a comprehensive framework for thinking about the process and intervention components needed for physician-based smoking intervention to take place in the health-care setting, the impact they have, and the eventual outcome of such interventions. There is a discussion of the challenges for the delivery of smoking-cessation services presented by the rapidly changing healthy delivery system of the 1990s. Finally, we present recommendations concerning research priorities for physician-based smoking intervention and the research funding process.

  11. Basic education and research in the classroom - doi: 10.4025/actascieduc.v35i2.20649

    Directory of Open Access Journals (Sweden)

    Nilda Stecanela

    2013-05-01

    Full Text Available Relationships between the challenges of Basic Education, especially those related to contemporary school, and the research-linked educational challenges are investigated, based on theoretical reflections on the employment of research in the classroom as an educational principle. The arguments are foregrounded on the analysis of aspects associated to the genesis of education and school crises. Current paper focuses on the importance of the teachers’ reflective practice and on their constitution as researchers-teachers for the implementation of the language game provided by classroom research, taking into consideration Freire’s dialogue. It underlines the active teaching methodologies that try to bridge the communication gap between school cultures and children’s and young people’s cultures, linked to everyday life dilemmas and with experience-built knowledge.

  12. Results of wholesomeness test on basic plan of research and development of food irradiation (7 items)

    International Nuclear Information System (INIS)

    Furuya, Tsuyoshi

    1989-01-01

    Twenty years have elapsed since the general research on food irradiation was begun in Japan as the new technology for food preservation, and the research on the wholesomeness of irradiated foods has been carried out in wide range together with the research on irradiation effect, irradiation techniques and economical efficiency. The wholesomeness of irradiated foods includes chronic toxicity including carcinogenic property in the continuous intake for long period, the effect to reproduction function over many generations and the possibility of giving hereditary injury to cells, the nutritional adequacy required for the sustenance of life and the increase of health, and microbiological safety. In Japan, the research on food irradiation was designated as an atomic energy specific general research, and as the objects of research, potato and onion for the prevention of germination, rice and wheat for the protection from noxious insects, fish paste products, wienerwurst and mandarin orange for sterilization were selected. For the irradiation, Co-60 gamma ray was used except the case of mandarin orange using electron beam. The research on all 7 items was finished, and the irradiation of potato was permitted. (K.I.)

  13. The Effect of Triptolide in Rheumatoid Arthritis: From Basic Research towards Clinical Translation

    Directory of Open Access Journals (Sweden)

    Danping Fan

    2018-01-01

    Full Text Available Triptolide (TP, a major extract of the herb Tripterygium wilfordii Hook F (TWHF, has been shown to exert potent pharmacological effects, especially an immunosuppressive effect in the treatment of rheumatoid arthritis (RA. However, its multiorgan toxicity prevents it from being widely used in clinical practice. Recently, several attempts are being performed to reduce TP toxicity. In this review, recent progress in the use of TP for RA, including its pharmacological effects and toxicity, is summarized. Meanwhile, strategies relying on chemical structural modifications, innovative delivery systems, and drug combinations to alleviate the disadvantages of TP are also reviewed. Furthermore, we also discuss the challenges and perspectives in their clinical translation.

  14. The role of basic research in the development of new processes

    International Nuclear Information System (INIS)

    Juentgen, H.; Heek, K.H. van; Klein, J.; Knoblauch, K.

    1981-01-01

    In many cases fundamental research is the starting point for the development of technical processes. This development will reach the aims successfully, if during the different phases - laboratory, semitechnical-plant, pilot plant, demonstration - results obtained from fundamental research can be used continuously. Also problems arising during the performance of the projects have to be solved by fundamental research. This interaction is discussed taking as examples the process development in the field of activated carbon application in energy- and environmental protection techniques and a modern coal gasification process development with nuclear process heat. (orig.) [de

  15. Basic research in crystalline and noncrystalline ceramic systems. Annual report, May 1, 1975--April 1, 1976

    International Nuclear Information System (INIS)

    1976-01-01

    Activities in research programs on ceramics are reported in sections on electric conductivity and dielectric properties, microstructure and properties, ion transport and diffusion, defect interactions and grain boundary phenomena, and future developments

  16. Project Summaries: Office of Basic Research Contract Program, 1989-1991

    Science.gov (United States)

    1990-08-01

    United States Army Research Institute for the BAhavioral and Social Sciences Approved !or public release; distribution is unlimited U.S. ARMY RESEARCH...Soldiers’ evaluation of their leaders in World WarII and the All- Volunteer Force. 27 (N): Group Functioning and Communicative Processes (0...Fischer, G. & Stevens, C. (1987) Volunteering Information: Enhancing the Communication Capabilities of Knowledge-Based Systems, Proceedings of INTERACT

  17. malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication

    Science.gov (United States)

    2017-01-01

    Basic science holds enormous power for revealing the biological mechanisms of disease and, in turn, paving the way toward new, effective interventions. Recognizing this power, the 2011 Research Agenda for Malaria Eradication included key priorities in fundamental research that, if attained, could help accelerate progress toward disease elimination and eradication. The Malaria Eradication Research Agenda (malERA) Consultative Panel on Basic Science and Enabling Technologies reviewed the progress, continuing challenges, and major opportunities for future research. The recommendations come from a literature of published and unpublished materials and the deliberations of the malERA Refresh Consultative Panel. These areas span multiple aspects of the Plasmodium life cycle in both the human host and the Anopheles vector and include critical, unanswered questions about parasite transmission, human infection in the liver, asexual-stage biology, and malaria persistence. We believe an integrated approach encompassing human immunology, parasitology, and entomology, and harnessing new and emerging biomedical technologies offers the best path toward addressing these questions and, ultimately, lowering the worldwide burden of malaria. PMID:29190277

  18. Algorithmic analysis of relational learning processes in instructional technology: Some implications for basic, translational, and applied research.

    Science.gov (United States)

    McIlvane, William J; Kledaras, Joanne B; Gerard, Christophe J; Wilde, Lorin; Smelson, David

    2018-07-01

    A few noteworthy exceptions notwithstanding, quantitative analyses of relational learning are most often simple descriptive measures of study outcomes. For example, studies of stimulus equivalence have made much progress using measures such as percentage consistent with equivalence relations, discrimination ratio, and response latency. Although procedures may have ad hoc variations, they remain fairly similar across studies. Comparison studies of training variables that lead to different outcomes are few. Yet to be developed are tools designed specifically for dynamic and/or parametric analyses of relational learning processes. This paper will focus on recent studies to develop (1) quality computer-based programmed instruction for supporting relational learning in children with autism spectrum disorders and intellectual disabilities and (2) formal algorithms that permit ongoing, dynamic assessment of learner performance and procedure changes to optimize instructional efficacy and efficiency. Because these algorithms have a strong basis in evidence and in theories of stimulus control, they may have utility also for basic and translational research. We present an overview of the research program, details of algorithm features, and summary results that illustrate their possible benefits. It also presents arguments that such algorithm development may encourage parametric research, help in integrating new research findings, and support in-depth quantitative analyses of stimulus control processes in relational learning. Such algorithms may also serve to model control of basic behavioral processes that is important to the design of effective programmed instruction for human learners with and without functional disabilities. Copyright © 2018 Elsevier B.V. All rights reserved.

  19. Research prioritization using the Analytic Hierarchy Process: basic methods. Volume 1

    International Nuclear Information System (INIS)

    Vesely, W.E.; Shafaghi, A.; Gary, I. Jr.; Rasmuson, D.M.

    1983-08-01

    This report describes a systematic approach for prioritizing research needs and research programs. The approach is formally called the Analytic Hierarchy Process which was developed by T.L. Saaty and is described in several of his texts referenced in the report. The Analytic Hierarchy Process, or AHP for short, has been applied to a wide variety of prioritization problems and has a good record of success as documented in Saaty's texts. The report develops specific guidelines for constructing the hierarchy and for prioritizing the research programs. Specific examples are given to illustrate the steps in the AHP. As part of the work, a computer code has been developed and the use of the code is described. The code allows the prioritizations to be done in a codified and efficient manner; sensitivity and parametric studies can also be straightforwardly performed to gain a better understanding of the prioritization results. Finally, as an important part of the work, an approach is developed which utilizes probabilistic risk analyses (PRAs) to systematically identify and prioritize research needs and research programs. When utilized in an AHP framework, the PRA's which have been performed to date provide a powerful information source for focusing research on those areas most impacting risk and risk uncertainty

  20. Personal historical chronicle of six decades of basic and applied research in virology, immunology, and vaccinology.

    Science.gov (United States)

    Hilleman, M R

    1999-08-01

    The sciences of vaccinology and of immunology were created just two centuries ago by Jenner's studies of prevention of smallpox by inoculation with cowpox virus. This rudimentary beginning was expanded greatly by the giants of late 19th and early 20th centuries biomedical sciences. The period from 1930 to 1950 was a transitional era with the introduction of chick embryos and minced tissues for propagating viruses and rickettsiae in vitro for vaccines. Modern era vaccinology began about 1950 as a continuum of notable advances made during the 1940s and World War II. Present vaccinology is based largely on breakthroughs in cell culture, bacterial polysaccharide chemistry, molecular biology, and immunology. By invitation, the author, who is a microbe hunter in fact, was asked to chronicle his six decades of pioneering achievements in basic and applied virology, bacteriology, immunology, molecular biology, epidemiology, and cancer, with special reference to the pioneering creation of most of the present day vaccines. Knowledge of the past may guide the present and future. This chronicle will have achieved its legacy if it helps others to understand the why and how of the past that may help to create the substance of the future.

  1. Instruction of Research-Based Comprehension Strategies in Basal Reading Programs

    Science.gov (United States)

    Pilonieta, Paola

    2010-01-01

    Research supports using research-based comprehension strategies; however, comprehension strategy instruction is not highly visible in basal reading programs or classroom instruction, resulting in many students who struggle with comprehension. A content analysis examined which research-based comprehension strategies were presented in five…

  2. Research on Energy Management Strategy of Hybrid Electric Vehicle

    Directory of Open Access Journals (Sweden)

    Deng Tao

    2015-01-01

    Full Text Available To improve the fuel economy and reduce emissions of hybrid electric vehicles, energy management strategy has received high attention. In this paper, by analyzing the deficiency of existing energy management strategy for hybrid cars, it not only puts forward the minimal equivalent fuel consumption adaptive strategy, but also is the first time to consider the driving dynamics target simultaneously, and to explain the future development direction of China’s hybrid energy management strategy.

  3. A Strategy for Nuclear Energy Research and Development

    International Nuclear Information System (INIS)

    Bennett, Ralph G.

    2008-01-01

    The United States is facing unprecedented challenges in climate change and energy security. President-elect Obama has called for a reduction of CO2 emissions to 1990 levels by 2020, with a further 80% reduction by 2050. Meeting these aggressive goals while gradually increasing the overall energy supply requires that all non-emitting technologies must be advanced. The development and deployment of nuclear energy can, in fact, help the United States meet several key challenges: (1) Increase the electricity generated by non-emitting sources to mitigate climate change, (2) Foster the safe and proliferation-resistant use of nuclear energy throughout the world, (3) Reduce the transportation sector's dependence on imported fossil fuels, and (4) Reduce the demand on natural gas for process heat and hydrogen production. However, because of the scale, cost, and time horizons involved, increasing nuclear energy's share will require a coordinated research effort-combining the efforts of industry and government, supported by innovation from the research community. This report outlines the significant nuclear energy research and development (R and D) necessary to create options that will allow government and industrial decision-makers to set policies and create nuclear energy initiatives that are decisive and sustainable. The nuclear energy R and D strategy described in this report adopts the following vision: Safe and economical nuclear energy in the United States will expand to address future electric and non-electric needs, significantly reduce greenhouse gas emissions and provide energy diversity, while providing leadership for safe, secure and responsible expansion of nuclear energy internationally

  4. Forest Service Global Change Research Strategy, 2009-2019 Implementation Plan

    Science.gov (United States)

    Allen Solomon; Richard A. Birdsey; Linda A. Joyce

    2010-01-01

    In keeping with the research goals of the U.S. Global Change Research Program, the climate change strategy of the U.S. Department of Agriculture (USDA), and the climate change framework of the Forest Service, this Forest Service Global Change Research Strategy, 2009-2019 Implementation Plan (hereafter called the Research Plan), was written by Forest Service Research...

  5. Proceeding of the Scientific Meeting and Presentation on Basic Research in Nuclear Science and Technology part II : Nuclear Chemistry, Process Technology, Radioactive Waste Management and Environment

    International Nuclear Information System (INIS)

    Sukarsono, R.; Ganang Suradjijo

    2002-01-01

    Scientific Meeting and Presentation on Basic Research in Nuclear Science and Technology is a routine activity held by Centre for Research and Development of Advanced Technology, National Nuclear Energy Agency, for monitoring the research activity which achieved in National Nuclear Energy Agency. This proceedings contains a proposal about basic research in nuclear technology which has environment. This proceedings is the second part of the two parts which published in series. There are 57 articles which have separated index. (PPIN)

  6. User Facilities of the Office of Basic Energy Sciences: A National Resource for Scientific Research

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-01-01

    The BES user facilities provide open access to specialized instrumentation and expertise that enable scientific users from universities, national laboratories, and industry to carry out experiments and develop theories that could not be done at their home institutions. These forefront research facilities require resource commitments well beyond the scope of any non-government institution and open up otherwise inaccessible facets of Nature to scientific inquiry. For approved, peer-reviewed projects, instrument time is available without charge to researchers who intend to publish their results in the open literature. These large-scale user facilities have made significant contributions to various scientific fields, including chemistry, physics, geology, materials science, environmental science, biology, and biomedical science. Over 16,000 scientists and engineers.pdf file (27KB) conduct experiments at BES user facilities annually. Thousands of other researchers collaborate with these users and analyze the data measured at the facilities to publish new scientific findings in peer-reviewed journals.

  7. From basic to applied research to improve outcomes for individuals who require augmentative and alternative communication: potential contributions of eye tracking research methods.

    Science.gov (United States)

    Light, Janice; McNaughton, David

    2014-06-01

    In order to improve outcomes for individuals who require AAC, there is an urgent need for research across the full spectrum--from basic research to investigate fundamental language and communication processes, to applied clinical research to test applications of this new knowledge in the real world. To date, there has been a notable lack of basic research in the AAC field to investigate the underlying cognitive, sensory perceptual, linguistic, and motor processes of individuals with complex communication needs. Eye tracking research technology provides a promising method for researchers to investigate some of the visual cognitive processes that underlie interaction via AAC. The eye tracking research technology automatically records the latency, duration, and sequence of visual fixations, providing key information on what elements attract the individual's attention (and which ones do not), for how long, and in what sequence. As illustrated by the papers in this special issue, this information can be used to improve the design of AAC systems, assessments, and interventions to better meet the needs of individuals with developmental and acquired disabilities who require AAC (e.g., individuals with autism spectrum disorders, Down syndrome, intellectual disabilities of unknown origin, aphasia).

  8. Basic research into eddy current testing of austenetic weld joints and surface claddings

    International Nuclear Information System (INIS)

    Meier, W.

    1976-01-01

    The result of research work has shown that the eddy-current testing method can be used for austenetic steel up to 10 mm thick to detect cracks in the material. An exception to this are laminations if they are parallel to the surface. Cracks in the various geometrical positions in the test specimen produce different results in the x-y plot. They are influenced by the direction of the material cracks. Research into the influence the geometric parameters have on the indications shows that the eddy-current method provides clearer interpretations of material cracks than any other non-destructive test method known. (orig.) [de

  9. The New Sepsis Definitions: Implications for the Basic and Translational Research Communities.

    Science.gov (United States)

    Coopersmith, Craig M; Deutschman, Clifford S

    2017-03-01

    New definitions of sepsis and septic shock were published in early 2016, updating old definitions that have not been revisited since 2001. These new definitions should profoundly affect sepsis research. In addition, these papers present clinical criteria for identifying infected patients who are highly likely to have or to develop sepsis or septic shock. In contrast to previous approaches, these new clinical criteria are evidence based. In this review, two of the authors of the new definitions detail the content of the papers and explore the implications for shock and sepsis researchers.

  10. The research strategy of the Swedish Nuclear Power Inspectorate

    International Nuclear Information System (INIS)

    2002-06-01

    In its directive to the Swedish Nuclear Power Inspectorate for 2001 and 2002, the Government asked for a report on SKI's future research strategy. This report is meant to describe future needs for SKI's regulatory and supervisory work, the need for expertise in Sweden and the possibility of international co-operation. SKI's research currently focuses on a number of strategically important areas such as reactor technology, materials and fuel issues, human factors, nuclear waste and nuclear safeguards. Over the past decade, the nuclear infrastructure has changed considerably. The nuclear power companies' previous organisations with specialist expertise and resources have been successively closed down or converted into consulting companies. Furthermore, education and research in the nuclear area at universities have been considerably reduced and expertise, resources and interest in the area have thereby decreased. A review of the availability of expertise in Sweden shows that, in many areas, resources are adequate, but that SKI, in certain cases, needs to provide focused support in order to maintain the expertise that SKI needs for its regulatory and supervisory activities. The analysis highlights two areas without any real education and research: 'Materials testing and control' and 'Management, control and organisation'. Education and research in the latter area lacks a safety perspective. SKI intends to take the initiative to conduct work within both of these areas. Since national research resources are limited, SKI has, for a long time, actively participated in international research. SKI is prioritising co-operation on research conducted in the OECD/NEA and is participating in a large number of projects organised within this framework. Since Sweden joined the EU, the importance of joint European work has increased. SKI is itself also actively participating and supporting Swedish organisations participating in European Commission projects and intends to support

  11. Basic Behavioral Science Research for Mental Health. Sociocultural and Environmental Processes.

    Science.gov (United States)

    American Psychologist, 1996

    1996-01-01

    Provides an overview of accomplishments in sociocultural and cross-cultural research and explores how culture influences the course of mental illness. The influence of race and ethnicity on mental health within a multicultural society is discussed as well as the influences of socioeconomic status, changing work roles, communities, and local…

  12. Programme Implementation in Social and Emotional Learning: Basic Issues and Research Findings

    Science.gov (United States)

    Durlak, Joseph A.

    2016-01-01

    This paper discusses the fundamental importance of achieving quality implementation when assessing the impact of social and emotional learning interventions. Recent findings in implementation science are reviewed that include a definition of implementation, its relation to programme outcomes, current research on the factors that affect…

  13. Basic Research Needs for Geosciences: Facilitating 21st Century Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    DePaolo, D. J.; Orr, F. M.; Benson, S. M.; Celia, M.; Felmy, A.; Nagy, K. L.; Fogg, G. E.; Snieder, R.; Davis, J.; Pruess, K.; Friedmann, J.; Peters, M.; Woodward, N. B.; Dobson, P.; Talamini, K.; Saarni, M.

    2007-06-01

    To identify research areas in geosciences, such as behavior of multiphase fluid-solid systems on a variety of scales, chemical migration processes in geologic media, characterization of geologic systems, and modeling and simulation of geologic systems, needed for improved energy systems.

  14. Derivation of Performance Statements for the Automotive Mechanics Basic Trade Course: Research Documentation.

    Science.gov (United States)

    Fox, A. P.; Kuhl, D. H.

    A project was conducted to derive a comprehensive list of the performances of a competence mechanic to satisfy the planning needs of automotive engineering lecturers, curriculum committees, researchers, course designers, and staff developers. A list of 127 tasks together with information about their relative importance and the frequency with which…

  15. The Translation of Basic Behavioral Research to School Psychology: A Citation Analysis

    Science.gov (United States)

    Reed, Derek D.

    2008-01-01

    In recent years, school psychology has become increasingly grounded in data-based decision making and intervention design, based upon behavior analytic principles. This paradigm shift has occurred in part by recent federal legislation, as well as through advances in experimental research replicating laboratory based studies. Translating basic…

  16. NCI Core Open House Shines Spotlight on Supportive Science and Basic Research | Poster

    Science.gov (United States)

    The lobby of Building 549 at NCI at Frederick bustled with activity for two hours on Tuesday, May 1, as several dozen scientists and staff gathered for the NCI Core Open House. The event aimed to encourage discussion and educate visitors about the capabilities of the cores, laboratories, and facilities that offer support to NCI’s Center for Cancer Research.

  17. Development of a control alternative for the citrus fruit borer, Ecdytolopha aurantiana (Lepidoptera, Tortricidae): from basic research to the grower

    International Nuclear Information System (INIS)

    Parra, Jose Roberto P.; Bento, Jose Mauricio S.; Yamamoto, Pedro T.; Vilela, Evaldo F.; Leal, Walter S.

    2004-01-01

    All research steps, developed from 1995 to 2000, to synthesize the sex pheromone of Ecdytolopha aurantiana (Lima, 1927) are described, in order to monitoring this pest that causes losses in the order of 50 million dollars per year to citriculture in the State of Sao Paulo. The basic researches conducted are described, including the development of an artificial diet for the insect, the study of its temperature and humidity requirements, behavioral studies, and synthesis of the male-attracting substance up to the formulation and distribution of the pheromone to the grower, by means of its commercialization. It is a case of success, at a cost of 50 thousand dollars, involving inter- and multidisciplinary researches, which can be adopted to other insect pests in the country. (author)

  18. Development of a control alternative for the citrus fruit borer, Ecdytolopha aurantiana (Lepidoptera, Tortricidae): from basic research to the grower

    Energy Technology Data Exchange (ETDEWEB)

    Parra, Jose Roberto P.; Bento, Jose Mauricio S. [Escola Superior de Agricultura Luiz de Queiroz (ESALQ/USP), Piracicaba, SP (Brazil). Dept. de Entomologia, Fitopatologia e Zoologia Agricola], e-mail: jrpparra@esalq.usp.br; Garcia, Mauro S. [Universidade Federal de Pelotas (UFPel), RS (Brazil); Yamamoto, Pedro T. [Fundo de Defesa da Citricultura (Fundecitrus), Araraquara, SP (Brazil); Vilela, Evaldo F. [Universidade Federal de Vicosa (UFV), MG (Brazil). Dept. de Biologia Animal; Leal, Walter S. [University of California, Davis, CA (Brazil). Dept. of Entomology

    2004-12-15

    All research steps, developed from 1995 to 2000, to synthesize the sex pheromone of Ecdytolopha aurantiana (Lima, 1927) are described, in order to monitoring this pest that causes losses in the order of 50 million dollars per year to citriculture in the State of Sao Paulo. The basic researches conducted are described, including the development of an artificial diet for the insect, the study of its temperature and humidity requirements, behavioral studies, and synthesis of the male-attracting substance up to the formulation and distribution of the pheromone to the grower, by means of its commercialization. It is a case of success, at a cost of 50 thousand dollars, involving inter- and multidisciplinary researches, which can be adopted to other insect pests in the country. (author)

  19. Implementation strategies of Systems Medicine in clinical research and home care for cardiovascular disease patients.

    Science.gov (United States)

    Montecucco, Fabrizio; Carbone, Federico; Dini, Frank Lloyd; Fiuza, Manuela; Pinto, Fausto J; Martelli, Antonietta; Palombo, Domenico; Sambuceti, Gianmario; Mach, François; De Caterina, Raffaele

    2014-11-01

    Insights from the "-omics" science have recently emphasized the need to implement an overall strategy in medical research. Here, the development of Systems Medicine has been indicated as a potential tool for clinical translation of basic research discoveries. Systems Medicine also gives the opportunity of improving different steps in medical practice, from diagnosis to healthcare management, including clinical research. The development of Systems Medicine is still hampered however by several challenges, the main one being the development of computational tools adequate to record, analyze and share a large amount of disparate data. In addition, available informatics tools appear not yet fully suitable for the challenge because they are not standardized, not universally available, or with ethical/legal concerns. Cardiovascular diseases (CVD) are a very promising area for translating Systems Medicine into clinical practice. By developing clinically applied technologies, the collection and analysis of data may improve CV risk stratification and prediction. Standardized models for data recording and analysis can also greatly broaden data exchange, thus promoting a uniform management of CVD patients also useful for clinical research. This advance however requires a great organizational effort by both physicians and health institutions, as well as the overcoming of ethical problems. This narrative review aims at providing an update on the state-of-art knowledge in the area of Systems Medicine as applied to CVD, focusing on current critical issues, providing a road map for its practical implementation. Copyright © 2014 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

  20. Maristem—Stem Cells of Marine/Aquatic Invertebrates: From Basic Research to Innovative Applications

    Directory of Open Access Journals (Sweden)

    Loriano Ballarin

    2018-02-01

    Full Text Available The “stem cells” discipline represents one of the most dynamic areas in biomedicine. While adult marine/aquatic invertebrate stem cell (MISC biology is of prime research and medical interest, studies on stem cells from organisms outside the classical vertebrate (e.g., human, mouse, and zebrafish and invertebrate (e.g., Drosophila, Caenorhabditis models have not been pursued vigorously. Marine/aquatic invertebrates constitute the largest biodiversity and the widest phylogenetic radiation on Earth, from morphologically simple organisms (e.g., sponges, cnidarians, to the more complex mollusks, crustaceans, echinoderms, and protochordates. These organisms contain a kaleidoscope of MISC-types that allow the production of a large number of novel bioactive-molecules, many of which are of significant potential interest for human health. MISCs further participate in aging and regeneration phenomena, including whole-body regeneration. For years, the European MISC-community has been highly fragmented and has established scarce ties with biomedical industries in an attempt to harness MISCs for human welfare. Thus, it is important to (i consolidate the European community of researchers working on MISCs; (ii promote and coordinate European research on MISC biology; (iii stimulate young researchers to embark on research in MISC-biology; (iv develop, validate, and share novel MISC tools and methodologies; (v establish the MISC discipline as a forefront interest of biomedical disciplines, including nanobiomedicine; and (vi establish collaborations with industries to exploit MISCs as sources of bioactive molecules. In order to fill the recognized gaps, the EC-COST Action 16203 “MARISTEM” has recently been launched. At its initial stage, the consortium unites 26 scientists from EC countries, Cooperating countries, and Near Neighbor Countries.

  1. How to create innovation by building the translation bridge from basic research into medicinal drugs: an industrial perspective.

    Science.gov (United States)

    Germann, Paul G; Schuhmacher, Alexander; Harrison, Juan; Law, Ronald; Haug, Kevin; Wong, Gordon

    2013-03-05

    The global healthcare industry is undergoing substantial changes and adaptations to the constant decline of approved new medical entities. This decrease in internal research productivity is resulting in a major decline of patent-protected sales (patent cliff) of most of the pharmaceutical companies. Three major global adaptive trends as driving forces to cope with these challenges are evident: cut backs of internal research and development jobs in the western hemisphere (Europe and USA), following the market growth potential of Asia by building up internal or external research and development capabilities there and finally, 'early innovation hunting' with an increased focus on identifying and investing in very early innovation sources within academia and small start-up companies. Early innovation hunting can be done by different approaches: increased corporate funding, establishment of translational institutions to bridge innovation, increasing sponsored collaborations and formation of technology hunting groups for capturing very early scientific ideas and concepts. This emerging trend towards early innovation hunting demands special adaptations from both the pharmaceutical industry and basic researchers in academia to bridge the translation into new medicines which deliver innovative medicines that matters to the patient. This opinion article describes the different modalities of cross-fertilisation between basic university or publicly funded institutional research and the applied research and development activities within the pharmaceutical industry. Two key factors in this important translational bridge can be identified: preparation of both partnering organisations to open up for new and sometime disruptive ideas and creation of truly trust-based relationships between the different groups allowing long-term scientific collaborations while acknowledging that value-creating differences are an essential factor for successful collaboration building.

  2. The Importance of basic Research for Inventions and Innovations in Wind Industry. Some Experiences from Denmark and China 1973 - 2011

    DEFF Research Database (Denmark)

    Pedersen, Jørgen Lindgaard; Xinxin, Kong

    Wind generated production of electricity by use of wind turbines began by inventions made at nearly the same time but independently by three natural science academic educated people as the Scotch professor in electrical technology James Blyth in 1887, the American mining engineer Charles F Brush...... from two Danish engineers H C Vogt and Johan Irminger who made basic research in aerodynamics a little bit of time before la Cour started up (Guy Larose and Niels Franck: Early wind engineering experiments in Denmark, in Journal of Wind Engineering and Industrial Aerodynamics, 72 (1997), pp. 493-499)...

  3. Characterizing researchers by strategies used for retaining minority participants: results of a national survey.

    Science.gov (United States)

    Butler, James; Quinn, Sandra C; Fryer, Craig S; Garza, Mary A; Kim, Kevin H; Thomas, Stephen B

    2013-09-01

    Limited attention has been given to the optimal strategies for retaining racial and ethnic minorities within studies and during the follow-up period. High attrition limits the interpretation of results and reduces the ability to translate findings into successful interventions. This study examined the retention strategies used by researchers when retaining minorities in research studies. From May to August 2010, we conducted an online survey with researchers (principal investigators, research staff, and IRB members) and examined their use of seven commonly used retention strategies. The number and type of retention strategies used, how these strategies differ by researcher type, and other characteristics (e.g., funding) were explored. We identified three clusters of researchers: comprehensive retention strategy researchers - utilized the greatest number of retention strategies; moderate retention strategy researchers - utilized an average number of retention strategies; and limited retention strategy researchers - utilized the least number of retention strategies. The comprehensive and moderate retention strategy researchers were more likely than the limited retention strategy researchers to conduct health outcomes research, work with a community advisory board, hire minority staff, use steps at a higher rate to overcome retention barriers, develop new partnerships with the minority community, modify study materials for the minority population, and allow staff to work flexible schedules. This study is a novel effort to characterize researchers, without implying a value judgment, according to their use of specific retention strategies. It provides critical information for conducting future research to determine the effectiveness of using a combination of retention strategies. Copyright © 2013. Published by Elsevier Inc.

  4. Advances in genetics and immunology: the importance of basic research to prevention of occupational diseases

    International Nuclear Information System (INIS)

    Omenn, G.S.

    1984-01-01

    Differences among workers in susceptibility to workplace exposures to environmental agents such as metals, ultraviolet radiation, and x-radiation are discussed. The distinction is made between the need for (1) monitoring for effects on the genetic material (genetic toxicology) and (2) screening for predisposing inherited traits (eco-genetics). Genetically-determined differences in susceptibility are discussed in relation to mechanisms of metabolism and of target sites. While there is not enough evidence to support routine genetic screening at this time there is common agreement that several promising areas for research on potential genetic predispositions warrant careful study. There is also reassuring evidence that productive relationships for research can be established among unions, management, and universities. 56 references, 3 figures, 7 tables

  5. Basic research in crystalline and noncrystalline ceramic systems. Annual report, May 1, 1976--April 31, 1977

    International Nuclear Information System (INIS)

    1977-01-01

    Research efforts from May 1, 1976 to April 31, 1977 are summarized. Twenty-one individual projects are described in four sections. The sections are: electrical, optical and dielectric properties of uranium dioxide, aluminum oxide, and magnesium oxide; microstructure development during processing and evolution in service under various driving forces, and effects on properties; kinetic studies including factors affecting ion transport and diffusion; and defect interactions, solute distribution, grain boundary phenomena and influence on properties

  6. Basic research of electro-rheological gel drum for novel linear actuator

    Energy Technology Data Exchange (ETDEWEB)

    Koyanagi, K; Yamaguchi, T; Oshima, T [Toyama Prefectural University, Toyama (Japan); Kakinuma, Y [Keio University, Kanagawa (Japan); Anzai, H; Sakurai, K [Fujikura Kasei, Tochigi (Japan)], E-mail: koyanagi@pu-toyama.ac.jp

    2009-02-01

    In recent years, robots that coexist with human are under active researches. Such robots need high safety, backdriveability, large generative force, high speed response, good controllability, and so on. We have put emphasis on the backdriveability and created a novel prototype linear actuator with an ER (Electro-Rheological) gel, a new functional material. It is an all-purpose actuator satisfying characteristics for human-coexistence welfare robot.

  7. Terrestrial Ecosystem Responses to Global Change: A Research Strategy

    Energy Technology Data Exchange (ETDEWEB)

    Ecosystems Working Group,

    1998-09-23

    Uncertainty about the magnitude of global change effects on terrestrial ecosystems and consequent feedbacks to the atmosphere impedes sound policy planning at regional, national, and global scales. A strategy to reduce these uncertainties must include a substantial increase in funding for large-scale ecosystem experiments and a careful prioritization of research efforts. Prioritization criteria should be based on the magnitude of potential changes in environmental properties of concern to society, including productivity; biodiversity; the storage and cycling of carbon, water, and nutrients; and sensitivity of specific ecosystems to environmental change. A research strategy is proposed that builds on existing knowledge of ecosystem responses to global change by (1) expanding the spatial and temporal scale of experimental ecosystem manipulations to include processes known to occur at large scales and over long time periods; (2) quantifying poorly understood linkages among processes through the use of experiments that manipulate multiple interacting environmental factors over a broader range of relevant conditions than did past experiments; and (3) prioritizing ecosystems for major experimental manipulations on the basis of potential positive and negative impacts on ecosystem properties and processes of intrinsic and/or utilitarian value to humans and on feedbacks of terrestrial ecosystems to the atmosphere. Models and experiments are equally important for developing process-level understanding into a predictive capability. To support both the development and testing of mechanistic ecosystem models, a two-tiered design of ecosystem experiments should be used. This design should include both (1) large-scale manipulative experiments for comprehensive testing of integrated ecosystem models and (2) multifactor, multilevel experiments for parameterization of process models across the critical range of interacting environmental factors (CO{sub 2}, temperature, water

  8. New approaches for managing preeclampsia: clues from clinical and basic research.

    Science.gov (United States)

    George, Eric M

    2014-12-01

    One of the most common, and most vexing, obstetric complications is preeclampsia-a major cause of maternal and perinatal morbidity. Hallmarked by new-onset hypertension and a myriad of other symptoms, the underlying cause of the disorder remains obscure despite intensive research into its etiology. Although the initiating events are not clear, one common finding in preeclamptic patients is failure to remodel the maternal arteries that supply the placenta, with resulting hypoxia/ischemia. Intensive research over the past 2 decades has identified several categories of molecular dysfunction resulting from placental hypoxia, which, when released into the maternal circulation, are involved in the spectrum of symptoms seen in these patients-in particular, angiogenic imbalance and the activation of innate and adaptive immune responses. Despite these new insights, little in the way of new treatments for the management of these patients has been advanced into clinical practice. Indeed, few therapeutic options exist for the obstetrician treating a case of preeclampsia. Pharmacologic management is typically seizure prophylaxis, and, in severe cases, antihypertensive agents for controlling worsening hypertension. Ultimately, the induction of labor is indicated, making preeclampsia a leading cause of premature birth. Here, the molecular mechanisms linking placental ischemia to the maternal symptoms of preeclampsia are reviewed, and several areas of recent research suggesting new potential therapeutic approaches to the management of preeclampsia are identified. Copyright © 2014 Elsevier HS Journals, Inc. All rights reserved.

  9. Basic Research on Selecting ISDC Activity for Decommissioning Costing in KRR-2 Decommissioning Project Experience Data

    Energy Technology Data Exchange (ETDEWEB)

    Song, Chan-Ho; Park, Hee-Seong; Jin, Hyung-Gon; Park, Seung-Kook [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    KAERI is performing research for calculation of expected time of a decommissioning work and evaluation of decommissioning cost and this research calculate a decommissioning work unit productivity based on the experience data of decommissioning activity for KRR-2. The KAERI be used to calculate the decommissioning cost and manage the experience data from the decommissioning activity through the Decommissioning Information Management System (DECOMMIS), Decommissioning Facility Characterization DB System (DEFACS), and Decommissioning Work-unit Productivity Calculation System (DEWOCS). In this paper, the methodology was presented how select the ISDC activities in dismantling work procedures of a 'removal of radioactive concrete'. The reason to select the 'removal of radioactive concrete' is main key activity and generates the amount of radioactive waste. This data will take advantage of the cost estimation after the code for the selected items derived ISDC. There are various efforts for decommissioning costing in each country. In particular, OECD/NEA recommends decommissioning cost estimation using the ISDC and IAEA provides for Cost Estimation for Research Reactors in Excel (CERREX) program that anyone is easy to use the cost evaluation from a limited decommissioning experience in domestic. In the future, for the decommissioning cost evaluation, the ISDC will be used more widely in a strong position. This paper has described a method for selecting the ISDC item from the actual dismantling work procedures.

  10. Compound facial expressions of emotion: from basic research to clinical applications

    Science.gov (United States)

    Du, Shichuan; Martinez, Aleix M.

    2015-01-01

    Emotions are sometimes revealed through facial expressions. When these natural facial articulations involve the contraction of the same muscle groups in people of distinct cultural upbringings, this is taken as evidence of a biological origin of these emotions. While past research had identified facial expressions associated with a single internally felt category (eg, the facial expression of happiness when we feel joyful), we have recently studied facial expressions observed when people experience compound emotions (eg, the facial expression of happy surprise when we feel joyful in a surprised way, as, for example, at a surprise birthday party). Our research has identified 17 compound expressions consistently produced across cultures, suggesting that the number of facial expressions of emotion of biological origin is much larger than previously believed. The present paper provides an overview of these findings and shows evidence supporting the view that spontaneous expressions are produced using the same facial articulations previously identified in laboratory experiments. We also discuss the implications of our results in the study of psychopathologies, and consider several open research questions. PMID:26869845

  11. Compound facial expressions of emotion: from basic research to clinical applications.

    Science.gov (United States)

    Du, Shichuan; Martinez, Aleix M

    2015-12-01

    Emotions are sometimes revealed through facial expressions. When these natural facial articulations involve the contraction of the same muscle groups in people of distinct cultural upbringings, this is taken as evidence of a biological origin of these emotions. While past research had identified facial expressions associated with a single internally felt category (eg, the facial expression of happiness when we feel joyful), we have recently studied facial expressions observed when people experience compound emotions (eg, the facial expression of happy surprise when we feel joyful in a surprised way, as, for example, at a surprise birthday party). Our research has identified 17 compound expressions consistently produced across cultures, suggesting that the number of facial expressions of emotion of biological origin is much larger than previously believed. The present paper provides an overview of these findings and shows evidence supporting the view that spontaneous expressions are produced using the same facial articulations previously identified in laboratory experiments. We also discuss the implications of our results in the study of psychopathologies, and consider several open research questions.

  12. Basic research on separation control of long life nuclides in fuel reprocessing processes

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Atsuyuki; Usami, Go [Tokyo Univ. (Japan). Faculty of Engineering; Maeda, Mitsuru; Fujine, Sachio; Uchiyama, Gunzo; Kihara, Takehiro; Asakura, Toshihide; Hotoku, Shinobu

    1996-01-01

    The behavior of technetium (Tc) in nuclear fuel reprocessing processes has become the subject to be elucidated in the transition to distribution process by coextraction and the catalytic action in distribution process. In order to forecast or control the behavior of Tc in reprocessing processes, it is necessary to understand that at which valence Tc exists stably in respective processes. Tc is stable at 7 valence in nitric acid solution expected in reprocessing. In this research, the reaction speed of the oxidation and reduction reactions of rhenium (Re) which simulates Tc was measured by laser Raman spectroscopy which can do high speed analysis of valence. The experimental method is explained. The Raman spectra of Re in the experimental system of this research were measured in perchloric acid solution and nitric acid solution, and compared with the values in literatures. As the result, the validity of this research was assured. It was confirmed that Re(7) was not reduced by sulfamic acid and ascorbic acid. Re(7) was reduced by thiocyanic acid once, but was oxidized again by the reaction of thiocyanic acid and nitric acid. (K.I.)

  13. Synchrotron X-ray scattering study on stratum corneum of skin. Toward applied research based upon basic research

    International Nuclear Information System (INIS)

    Hatta, Ichiro; Ohta, Noboru; Yagi, Naoto

    2008-01-01

    On considering the applied research on stratum corneum of skin, it is indispensable to know the structure at the molecular level. However, there is even now in a controversy among the researchers who are performing its X-ray scattering study. Here we introduce our solution for the two problems: One is the correlation between the lamellar structures and hydrocarbon-chain packings in intercellular lipid matrix and the other is the existence of water layers in the short lamellar structure. These studies have become possible for the first time by making good use of synchrotron small-angle/wide-angle X-ray diffraction. Based upon the structural evidence, we can further carry out the applied research in stratum corneum. (author)

  14. Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment

    Directory of Open Access Journals (Sweden)

    Jaume Folch

    2016-01-01

    Full Text Available Alzheimer’s disease (AD currently presents one of the biggest healthcare issues in the developed countries. There is no effective treatment capable of slowing down disease progression. In recent years the main focus of research on novel pharmacotherapies was based on the amyloidogenic hypothesis of AD, which posits that the beta amyloid (Aβ peptide is chiefly responsible for cognitive impairment and neuronal death. The goal of such treatments is (a to reduce Aβ production through the inhibition of β and γ secretase enzymes and (b to promote dissolution of existing cerebral Aβ plaques. However, this approach has proven to be only modestly effective. Recent studies suggest an alternative strategy centred on the inhibition of the downstream Aβ signalling, particularly at the synapse. Aβ oligomers may cause aberrant N-methyl-D-aspartate receptor (NMDAR activation postsynaptically by forming complexes with the cell-surface prion protein (PrPC. PrPC is enriched at the neuronal postsynaptic density, where it interacts with Fyn tyrosine kinase. Fyn activation occurs when Aβ is bound to PrPC-Fyn complex. Fyn causes tyrosine phosphorylation of the NR2B subunit of metabotropic glutamate receptor 5 (mGluR5. Fyn kinase blockers masitinib and saracatinib have proven to be efficacious in treating AD symptoms in experimental mouse models of the disease.

  15. Communication masking in marine mammals: A review and research strategy.

    Science.gov (United States)

    Erbe, Christine; Reichmuth, Colleen; Cunningham, Kane; Lucke, Klaus; Dooling, Robert

    2016-02-15

    Underwater noise, whether of natural or anthropogenic origin, has the ability to interfere with the way in which marine mammals receive acoustic signals (i.e., for communication, social interaction, foraging, navigation, etc.). This phenomenon, termed auditory masking, has been well studied in humans and terrestrial vertebrates (in particular birds), but less so in marine mammals. Anthropogenic underwater noise seems to be increasing in parts of the world's oceans and concerns about associated bioacoustic effects, including masking, are growing. In this article, we review our understanding of masking in marine mammals, summarise data on marine mammal hearing as they relate to masking (including audiograms, critical ratios, critical bandwidths, and auditory integration times), discuss masking release processes of receivers (including comodulation masking release and spatial release from masking) and anti-masking strategies of signalers (e.g. Lombard effect), and set a research framework for improved assessment of potential masking in marine mammals. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  16. European Fusion Materials Research Program - Recent Results and Future Strategy

    International Nuclear Information System (INIS)

    Diegele, E.; Andreani, R.; Laesser, R.; Schaaf, B. van der

    2005-01-01

    The paper reviews the objectives and the status of the current EU long-term materials program. It highlights recent results, discusses some of the key issues and major existing problems to be resolved and presents an outlook on the R and D planned for the next few years. The main objectives of the Materials Development program are the development and qualification of reduced activation structural materials for the Test Blanket Modules (TBMs) in ITER and of low activation structural materials resistant to high fluence neutron irradiation for in-vessel components such as breeding blanket, divertor and first wall in DEMO. The EU strategy assumes: (i) ITER operation starting in 2015 with DEMO relevant Test Blanket Modules to be installed from day one of operation, (ii) IFMIF operation in 2017 and (iii) DEMO final design activities in 2022 to 2025. The EU candidate structural material EUROFER for TBMs has to be fully code qualified for licensing well before 2015. In parallel, research on materials for operation at higher temperatures is conducted following a logical sequence, by supplementing EUROFER with the oxide dispersion strengthened ferritic steels and, thereafter, with fibre-reinforced Silicon Carbide (SiC f /SiC). Complementary, tungsten alloys are developed as structural material for high temperature applications such as gas-cooled divertors

  17. 2004 Space Report: Environment and Strategy for Space Research at NATO's Research and Technology Organisation (RTO)

    Science.gov (United States)

    Woods-Vedeler, Jessica A.

    2007-01-01

    This report describes the motivation for and a strategy to enhance the NATO Research and Technology Organisation's (RTO) current space research effort to reflect NATO's growing military dependence on space systems. Such systems and services provided by these systems are critical elements of military operations. NATO uses space systems for operational planning and support, communication, radio navigation, multi-sensor and multi-domain demonstrations. Such systems are also used to promote regional stability. A quantitative analysis of work related to space in the NATO RTO showed that during the period of 1998 - 2004, 5% of the research pursued in the NATO RTO has been clearly focused on space applications. Challenging environmental and organizational barriers for increasing RTO space research were identified. In part, these include lack of sufficient space expertise representation on panels, the military sensitivity of space, current panel work loads and the need for specific technical recommendations from peers. A strategy for enhancing space research in the RTO is to create a limited-life Space Advisory Group (SAG) composed of Space Expert Consultants who are panel members with appropriate expertise and additional expertise from the nations. The SAG will recommend and find support in the nations for specific technical activities related to space in the areas of Space Science, Remote Sensing Data Analysis, Spacecraft Systems, Surveillance and Early Warning, Training and Simulation and Policy. An RTO Space Advisory Group will provide an organizational mechanism to gain recognition of RTO as a forum for trans-Atlantic defence space research and to enhance space research activities.

  18. Basic research in crystalline and noncrystalline ceramic systems. Annual report, August 1, 1978-October 31, 1979

    International Nuclear Information System (INIS)

    1979-01-01

    Research is reported in optical and dielectric properties of MgO, aluminium oxide, and y-doped UO 2 ; kinetic studies of MgO, magnesium hydroxide, KCl-doped SrCl 2 , KCl, and Al 2 O 3 ; defect structures of MgO, ZnO-Bi 2 O 3 , SiC, Sc 2 O 3 , Al 2 O 3 , Cr 2 O 3 , and SiO 2 ; sintering studies of alumina; and mechanical properties of UO 2 , Al 2 O 3 , and creep in W

  19. Basic Research on Remote Sensing of Fissile Materials utilizing Gamma-rays and Neutrons

    Science.gov (United States)

    2017-02-01

    years, and an atomic mass number less than 60 was initially created for the proposal. From that list the student eliminated all reactions with an...decided that a lithium film grown on a nickel substrate and covered with a nickel film would be a good approach. They have learnt how to prepare thin...Nuclear Instruments and Methods in Physics Research A. 505 (2003) 1-4. 0 1 2 3 4 Shown in Figure 3 are key data taken with the lithium glass detectors

  20. Basic research in homeopathy and ultra-high dilutions: what progress is being made?

    Science.gov (United States)

    Betti, Lucietta; Trebbi, Grazia; Olioso, Debora; Marzotto, Marta; Bellavite, Paolo

    2013-04-01

    This report summarises the latest research developments in the field of high dilutions and homeopathy, as presented at the GIRI symposium of the leading international organisation of scientists in this field, in Florence, Italy in September 2012. The scientific community's early scepticism concerning the possible biological and pharmacological activity of highly diluted solutions, is giving way to a more open-minded attitude that no longer obstructs critical and experimental investigations in this emerging field of biomedicine. Copyright © 2013. Published by Elsevier Ltd.. All rights reserved.