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Sample records for strain imi sd

  1. Lattice strain evolution in IMI 834 under applied stress

    International Nuclear Information System (INIS)

    Daymond, Mark R.; Bonner, Neil W.

    2003-01-01

    The effect of elastic and plastic anisotropy on the evolution of lattice strains in the titanium alloy IMI834 has been examined during a uniaxial tensile test, by in situ monitoring on the Engin instrument at the ISIS pulsed neutron source. Measurements were made at load during an incremental loading test. The data is analysed in the light of the requirements for engineering residual stress scanning measurements performed at polychromatic neutron and synchrotron diffraction sources. Comparisons between the measured strains from different lattice families and the predictions from an elasto-plastic self-consistent model are made. Agreement is good in the elastic regime and for most diffraction planes in the plastic regime

  2. Nitrogen Source Stabilization of Quorum Sensing in the Pseudomonas aeruginosa Bioaugmentation Strain SD-1.

    Science.gov (United States)

    Wang, Mei-Zhen; Lai, Bai-Min; Dandekar, Ajai A; Yang, Yu-Sheng; Li, Na; Yin, Jun; Shen, Dong-Sheng

    2017-08-15

    Pseudomonas aeruginosa SD-1 is efficient at degrading aromatic compounds and can therefore contribute to the bioremediation of wastewater. P. aeruginosa uses quorum sensing (QS) to regulate the production of numerous secreted "public goods." In wastewater bioaugmentation applications, there are myriad nitrogen sources, and we queried whether various nitrogen sources impact the stabilities of both QS and the bacterial populations. In a laboratory strain of P. aeruginosa , PAO1, the absence of a nitrogen source has been shown to destabilize these populations through the emergence of QS mutant "cheaters." We tested the ability of SD-1 to grow in casein broth, a condition that requires QS for growth, when the nitrogen source with either NH 4 Cl, NaNO 3 , or NaNO 2 or with no added nitrogen source. There was great variability in susceptibility to invasion by QS mutant cheaters and, by extension, the stability of the SD-1 population. When grown with NH 4 Cl as an extra nitrogen source, no population collapse was observed; by contrast, two-thirds of cultures grown in the presence of NaNO 2 collapsed. In the populations that collapsed, the frequency of social cheaters exceeded 40%. NaNO 3 and NaNO 2 directly favor QS mutants of P. aeruginosa SD-1. Although the mechanism by which these nitrogen sources act is not clear, these data indicate that the metabolism of nitrogen can affect the stability of bacterial populations, an important observation for continuing industrial applications with this species. IMPORTANCE Bioaugmentation as a method to help remediate wastewater pollutant streams holds significant potential to enhance traditional methods of treatment. Addition of microbes that can catabolize organic pollutants can be an effective method to remove several toxic compounds. Such bioaugmented strains of bacteria have been shown to be susceptible to competition from the microbiota that are present in wastewater streams, limiting their potential effectiveness. Here, we

  3. Extracellular Pectinase from a Novel Bacterium Chryseobacterium indologenes Strain SD and Its Application in Fruit Juice Clarification

    Directory of Open Access Journals (Sweden)

    Karabi Roy

    2018-01-01

    Full Text Available Pectinase is one of the important enzymes of industrial sectors. Presently, most of the pectinases are of plant origin but there are only a few reports on bacterial pectinases. The aim of the present study was to isolate a novel and potential pectinase producing bacterium as well as optimization of its various parameters for maximum enzyme production. A total of forty bacterial isolates were isolated from vegetable dump waste soil using standard plate count methods. Primary screening was done by hydrolysis of pectin. Pectinase activity was determined by measuring the increase in reducing sugar formed by the enzymatic hydrolysis of pectin. Among the bacterial isolates, the isolate K6 exhibited higher pectinase activity in broth medium and was selected for further studies. The selected bacterial isolate K6 was identified as Chryseobacterium indologenes strain SD. The isolate was found to produce maximum pectinase at 37°C with pH 7.5 upon incubation for 72 hours, while cultured in production medium containing citrus pectin and yeast extract as C and N sources, respectively. During enzyme-substrate reaction phase, the enzyme exhibited its best activity at pH of 8.0 and temperature of 40°C using citrus pectin as substrate. The pectinase of the isolate showed potentiality on different types of fruit juice clarification.

  4. Production and Characterization of Alkaline Protease from a High Yielding and Moderately Halophilic Strain of SD11 Marine Bacteria

    Directory of Open Access Journals (Sweden)

    Hongxia Cui

    2015-01-01

    Full Text Available A marine bacterium SD11, which was isolated from sea muds (Geziwo Qinhuangdao Sea area, China, was used to produce thermostable alkaline serine nonmetal protease in the skim milk agar plate medium with 10% NaCl. The optimal temperature about the manufacture of the extracellular protease was ~60°C. The crude enzyme was stable at 20–50°C. The activity was retained to 60% and 45% after heating for 1 h at 60 and 70°C, respectively. The protease was highly active in a wide pH scope (8.0–10.0 and maximum protease activity exhibited at pH 10.0. The activity was restrained by phenylmethylsulfonyl fluoride (PMSF but mildly increased (~107% in the presence of ethylenediaminetetraacetic acid (EDTA, indicating that the production contains serine-protease(s and nonmetal protease(s. Moreover, the crude alkaline protease was active with the 5 mM Ca2+, Mn2+, Zn2+, Cu2+, Na+, and K+ that existed separately. In addition, the protease showed superduper stability when exposed to an anionic surfactant (5 mM SDS, an oxidizing agent (1% H2O2, and several organic solvents (methanol, isopropanol, and acetone. These results suggest that the marine bacterium SD11 is significant in the industry from the prospects of its ability to produce thermally stable alkaline protease.

  5. IMIS as an information engineering system

    International Nuclear Information System (INIS)

    Leeb, H.

    1992-01-01

    A precondition for the functionality of the decentrally organized system IMIS-IT is the clear-cut distribution of tasks and competences in an operational concept. It distinguishes between task areas which are handled centrally by the Federal Office of Radiation Protection, in particular by the ZdB and task areas which are handled decentrally by Land data centers, federal authorities and Land state measuring points. An overview of the IMIS-IT network with its hardware and software components is provided. (DG) [de

  6. IMI's teaching design, feedback system and its localization

    Science.gov (United States)

    Wen, Tingting; Zhang, Xuexin

    2017-08-01

    In Britain, the Institute of the Motor Industry (IMI) sets the National Occupational Standards for all sectors of the automotive industry. The IMI certificate and associated training programs are well recognized for its high quality both in the United Kingdom (UK) and internationally. Using China's first groups studying IMI Level 3 certificate for teachers and Level 2 certificate for students as a sample, we analyzed the seven central aspects in IMI teaching, namely, assessment standard, environment, method, content, procedure, quality control and feedback. We then proposed strategies and guidelines for its localization in China, which would be particularly important for the establishment and expansion of IMI centers.

  7. Status report of IMIS-IT

    International Nuclear Information System (INIS)

    1992-01-01

    The papers presented to the review seminar on the IMIS-IT project (Integriertes Mess- und InformationsSystem - InformationsTechnik) show the major results achieved, experience gained, and planned future activities. Up to that date, data processing problems were rather dominating, also because subject-related aspects or problems for some part were recognized or emerged only after the project became operational. (BBR) [de

  8. X-ray Absorption Spectroscopy of the Zinc-Binding Sites in the Class B2 Metallo-B-lactamsase ImiS from Aeromonas veronii bv. sobria

    Energy Technology Data Exchange (ETDEWEB)

    Costello,A.; Sharma, N.; Yang, K.; Crowder, M.; Tierney, D.

    2006-01-01

    X-ray absorption spectroscopy was used to investigate the metal-binding sites of ImiS from Aeromonas veronii bv. sobria in catalytically active (1-Zn), product-inhibited (1-Zn plus imipenem), and inactive (2-Zn) forms. The first equivalent of zinc(II) was found to bind to the consensus Zn{sub 2} site. The reaction of 1-Zn ImiS with imipenem leads to a product-bound species, coordinated to Zn via a carboxylate group. The inhibitory binding site of ImiS was examined by a comparison of wild-type ImiS with 1 and 2 equiv of bound zinc. 2-Zn ImiS extended X-ray absorption fine structure data support a binding site that is distant from the active site and contains both one sulfur donor and one histidine ligand. On the basis of the amino acid sequence of ImiS and the crystal structure of CphA [Garau et al. (2005) J. Mol. Biol. 345, 785-795], we propose that the inhibitory binding site is formed by M146, found on the B2-distinct {alpha}3 helix, and H118, a canonical Zn{sub 1} ligand, proposed to help activate the nucleophilic water. The mutation of M146 to isoleucine abolishes metal inhibition. This is the first characterization of ImiS with the native metal Zn and establishes, for the first time, the location of the inhibitory metal site.

  9. IT-technical innovations in the new IMIS system

    International Nuclear Information System (INIS)

    Leeb, H.

    2003-01-01

    The most important innovation in the new IMIS System will be - Use of an up-to-date system platform - Improvement of the user interface - Improvement of the response time of the system. The IMIS application software will entirely be realised with Java. Data base software will still be ORACLE, GIS software will be GISTerm and the OSS software product Zope will be used as Content Management System. The new IMIS will be very flexible with respect to representations, work flows and data flows. The most important innovation for the users will be that the ''normal'' user will not be forced to produce his own data representations and evaluations but can use automatically generated ''documents'' using a standard browser for visualisation. Another important innovation is the renunciation of data base servers at the central offices of the federal states and the centres of the federal networks. So only one server with a high redundancy will exist in the IMIS network. This talk deals with the state of the IMIS project, the architecture of the new IMIS, the availability of the central server and the changes in the operating of the new system. (orig.)

  10. IMIS: An intelligence microscope imaging system

    Science.gov (United States)

    Caputo, Michael; Hunter, Norwood; Taylor, Gerald

    1994-01-01

    Until recently microscope users in space relied on traditional microscopy techniques that required manual operation of the microscope and recording of observations in the form of written notes, drawings, or photographs. This method was time consuming and required the return of film and drawings from space for analysis. No real-time data analysis was possible. Advances in digital and video technologies along with recent developments in article intelligence will allow future space microscopists to have a choice of three additional modes of microscopy: remote coaching, remote control, and automation. Remote coaching requires manual operations of the microscope with instructions given by two-way audio/video transmission during critical phases of the experiment. When using the remote mode of microscopy, the Principal Investigator controls the microscope from the ground. The automated mode employs artificial intelligence to control microscope functions and is the only mode that can be operated in the other three modes as well. The purpose of this presentation is to discuss the advantages and disadvantages of the four modes of of microscopy and how the IMIS, a proposed intelligent microscope imaging system, can be used as a model for developing and testing concepts, operating procedures, and equipment design of specifications required to provide a comprehensive microscopy/imaging capability onboard Space Station Freedom.

  11. IMI's CANCER-ID: Status of liquid biopsy standardization

    NARCIS (Netherlands)

    Pantel, Klaus; Terstappen, Leon W. M. M.; Baggiani, Barbara; Krahn, Thomas; Schlange, Thomas

    The CANCER-ID (www.cancer-id.eu) consortium was established in early 2015 with more than 30 partners as part of the Innovative Medicines Initiative (IMI), Europe's largest public-private partnership funded in equal parts by the European Union and the European Federation of Pharmaceutical Industries

  12. Elucidation of a carotenoid biosynthesis gene cluster encoding a novel enzyme, 2,2'-beta-hydroxylase, from Brevundimonas sp. strain SD212 and combinatorial biosynthesis of new or rare xanthophylls.

    Science.gov (United States)

    Nishida, Yasuhiro; Adachi, Kyoko; Kasai, Hiroaki; Shizuri, Yoshikazu; Shindo, Kazutoshi; Sawabe, Akiyoshi; Komemushi, Sadao; Miki, Wataru; Misawa, Norihiko

    2005-08-01

    A carotenoid biosynthesis gene cluster mediating the production of 2-hydroxyastaxanthin was isolated from the marine bacterium Brevundimonas sp. strain SD212 by using a common crtI sequence as the probe DNA. A sequence analysis revealed this cluster to contain 12 open reading frames (ORFs), including the 7 known genes, crtW, crtY, crtI, crtB, crtE, idi, and crtZ. The individual ORFs were functionally analyzed by complementation studies using Escherichia coli that accumulated various carotenoid precursors due to the presence of other bacterial crt genes. In addition to functionally identifying the known crt genes, we found that one (ORF11, named crtG) coded for a novel enzyme, carotenoid 2,2'-beta-hydroxylase, which showed intriguingly partial homology with animal sterol-C5-desaturase. When this crtG gene was introduced into E. coli accumulating zeaxanthin and canthaxanthin, the resulting transformants produced their 2-hydroxylated and 2,2'-dihydroxylated products which were structurally novel or rare xanthophylls, as determined by their nuclear magnetic resonance and high-performance liquid chromatography/photodiode array detector/atmospheric pressure chemical ionization mass spectrometry spectral data. The new carotenoid produced was suggested to have a strong inhibitory effect on lipid peroxidation.

  13. Elucidation of a Carotenoid Biosynthesis Gene Cluster Encoding a Novel Enzyme, 2,2′-β-Hydroxylase, from Brevundimonas sp. Strain SD212 and Combinatorial Biosynthesis of New or Rare Xanthophylls

    Science.gov (United States)

    Nishida, Yasuhiro; Adachi, Kyoko; Kasai, Hiroaki; Shizuri, Yoshikazu; Shindo, Kazutoshi; Sawabe, Akiyoshi; Komemushi, Sadao; Miki, Wataru; Misawa, Norihiko

    2005-01-01

    A carotenoid biosynthesis gene cluster mediating the production of 2-hydroxyastaxanthin was isolated from the marine bacterium Brevundimonas sp. strain SD212 by using a common crtI sequence as the probe DNA. A sequence analysis revealed this cluster to contain 12 open reading frames (ORFs), including the 7 known genes, crtW, crtY, crtI, crtB, crtE, idi, and crtZ. The individual ORFs were functionally analyzed by complementation studies using Escherichia coli that accumulated various carotenoid precursors due to the presence of other bacterial crt genes. In addition to functionally identifying the known crt genes, we found that one (ORF11, named crtG) coded for a novel enzyme, carotenoid 2,2′-β-hydroxylase, which showed intriguingly partial homology with animal sterol-C5-desaturase. When this crtG gene was introduced into E. coli accumulating zeaxanthin and canthaxanthin, the resulting transformants produced their 2-hydroxylated and 2,2′-dihydroxylated products which were structurally novel or rare xanthophylls, as determined by their nuclear magnetic resonance and high-performance liquid chromatography/photodiode array detector/atmospheric pressure chemical ionization mass spectrometry spectral data. The new carotenoid produced was suggested to have a strong inhibitory effect on lipid peroxidation. PMID:16085816

  14. IMI Workshop on Optimization in the Real World

    CERN Document Server

    Shinano, Yuji; Waki, Hayato

    2016-01-01

    This book clearly shows the importance, usefulness, and powerfulness of current optimization technologies, in particular, mixed-integer programming and its remarkable applications. It is intended to be the definitive study of state-of-the-art optimization technologies for students, academic researchers, and non-professionals in industry. The chapters of this book are based on a collection of selected and extended papers from the  “IMI Workshop on Optimization in the Real World” held in October 2014 in Japan.

  15. Discovery of the target for immunomodulatory drugs (IMiDs).

    Science.gov (United States)

    Ito, Takumi; Ando, Hideki; Handa, Hiroshi

    2016-05-01

    Half a century ago, the sedative thalidomide caused a serious drug disaster because of its teratogenicity and was withdrawn from the market. However, thalidomide, which has returned to the market, is now used for the treatment of leprosy and multiple myeloma (MM) under strict control. The mechanism of thalidomide action had been a long-standing question. We developed a new affinity bead technology and identified cereblon (CRBN) as a thalidomide-binding protein. We found that CRBN functions as a substrate receptor of an E3 cullin-Ring ligase complex 4 (CRL4) and is a primary target of thalidomide teratogenicity. Recently, new thalidomide derivatives, called immunomodulatory drugs (IMiDs), have been developed by Celgene. Among them, lenalidomide (Len) and pomalidomide (Pom) were shown to exert strong therapeutic effects against MM. It was found that Len and Pom both bind CRBN-CRL4 and recruit neomorphic substrates (Ikaros and Aiolos). More recently it was reported that casein kinase 1a (Ck1a) was identified as a substrate for CRBN-CRL4 in the presence of Len, but not Pom. Ck1a breakdown explains why Len is specifically effective for myelodysplastic syndrome with 5q deletion. It is now proposed that binding of IMiDs to CRBN appears to alter the substrate specificity of CRBN-CRL4. In this review, we introduce recent findings on IMiDs.

  16. Creep-fatigue behaviour of the titanium alloy IMI 834 at 600 C

    International Nuclear Information System (INIS)

    Nowack, H.; Kordisch, T.

    1998-01-01

    In the present study the creep-fatigue behaviour of the titanium alloy IMI 834 at 600 C was investigated. A comparison of the crack initiation life behaviour and of the crack propagation as caused by different types of complex creep-fatigue cycles (with hold times into tension and/or into compression direction and with different loading rates into tension and/or into compression direction) showed, that a slow increase of the loadings into tension reduced the life and increased the crack velocity more than hold times at the maximum load. Furthermore, there existed environmental influences. On the basis of the experimental investigations the prediction capability of convenient crack initiation life prediction methods was evaluated. It turned out that the prediction capability of the strain range partitioning method could be improved if it was frequency modified. The prediction capability of the frequency modification method could also be improved, if mean stresses in the cycles were explicitely accounted for. In the short and long crack stage the propagation behaviour could be correlated well if the effective cyclic J-integral was used. This is of importance for damage tolerance considerations. Because the strains and the stresses at the crack tip are most important for the crack propagation behaviour, they were analysed on the basis of the finite element method. It was found that the strains and stresses differed for different types of creep-fatigue cycles. (orig.)

  17. Optimization of the German integrated information and measurement system (IMIS)

    International Nuclear Information System (INIS)

    Wirth, E.; Weiss, W.

    2002-01-01

    The Chernobyl accident led to a widespread contamination of the environment in most European countries. In Germany, like in all other countries, it took some time to evaluate the radiological situation, time which is extremely valuable in the early phases of an accident when decisions on countermeasures like sheltering, iodine prophylaxis or evacuation have to be taken. For a better emergency preparedness the Integrated Information and Measurement System (IMIS) has been developed and established in Germany. In case of a widespread contamination of the environment, the system will provide the decision makers with all information necessary to evaluate the radiological situation and to decide on countermeasures. Presently this system is upgraded due to the adoption of the European decision supporting system RODOS and by the improvement of the national information exchange. For this purpose the web based information system ELAN has been developed. The national systems have to be integrated into the European and international communication systems. In this presentation the IMIS system is briefly described and the new features and modules of the system are discussed in greater detail

  18. An example of technological transfer to industry: the 'IMI' project

    International Nuclear Information System (INIS)

    Stefanini, A.; Amendolia, S.R.; Annovazzi, A.; Baldelli, P.; Bigongiari, A.; Bisogni, M.G.; Catarsi, F.; Cetronio, A.; Chianella, M.; Cinti, M.N.; Delogu, P.; Fantacci, M.E.; Galimberti, D.; Gambaccini, M.; Gilardoni, C.; Iurlaro, G.; Lanzieri, C.; Meoni, M.; Novelli, M.; Pani, R.; Passuello, G.; Pellegrini, R.; Pieracci, M.; Quattrocchi, M.; Rosso, V.; Venturelli, L.

    2004-01-01

    Several INFN Sections and Departments of Physics of Italian Universities have spent many man-years in the attempt to adapt detector and read-out technologies, originally developed in the field of High Energy Physics, to the domain of biomedical apparatuses. The research covered such areas as the exploitation of crystals for the production of monochromatic X-ray beams, the development of devices for efficient X-ray detection, the design of advanced VLSI electronics, the improvement of Position Sensitive Photomultiplier Tubes and crystals for Nuclear Medicine gamma-cameras. These studies have been integrated in the Integrated Mammographic Imaging (IMI) project, funded by the Italian Government through the law 46/82 (art.10) and is carried on by five high-technology industries in Italy, namely LABEN, CAEN, AMS, GILARDONI and POL.HI.TECH. We report on the status of this technological transfer project

  19. Hot ductility behavior of near-alpha titanium alloy IMI834

    International Nuclear Information System (INIS)

    Ghavam, Mohammad Hadi; Morakabati, Maryam; Abbasi, Seyed Mahdi; Badri, Hassan

    2014-01-01

    The hot ductility of rolled IMI834 titanium alloy (Ti-5.3Al-2.9Sn-3.0Zr-0.65Nb-0.5Mo-0.2Si in wt%) has been studied by conducting tensile tests with a strain rate of 0.1 s -1 and temperature range of 750-1100 C to obtain the optimum hot working conditions. The alloy showed minimum hot ductility in the lower alpha-beta region in the temperature range 750-950 C. Further microstructural characterizations showed improvement in hot ductility by increasing temperature, which was attributed to reduction of volume fraction of high strength alpha phase. The best hot ductility was observed at 1000 C, i.e. in the upper alpha-beta region. The better hot ductility at higher temperature could be related to the increase in the volume fraction of beta phase and the occurrence of dynamic restoration phenomena. The second decline in hot ductility appeared at higher temperatures in the beta region and was attributed to the high stacking fault energy and self-diffusion of beta phase leading to limitation of dynamic recrystallization.

  20. Oxidation behaviour of the near α-titanium alloy IMI 834

    Indian Academy of Sciences (India)

    Unknown

    Oxidation behaviour of the near α-titanium alloy IMI 834 was investigated over a range of tem- peratures, from ... perties and adequate resistance against environmental degradation. ... the change of weight of the specimen. The oxidation data.

  1. Improving Leadership Training at the United States Naval Academy by Utilizing Interactive Multimedia Instruction (IMI)

    National Research Council Canada - National Science Library

    Kawane, Shannon

    1999-01-01

    ... a program consistent with the Naval Academy's leadership training philosophy. The results suggest that an IMI program can be developed that is consistent with the Naval Academy's leadership development program...

  2. Ka Hana `Imi Na`auao: A Science Curriculum Project

    Science.gov (United States)

    Napeahi, K.; Roberts, K. D.; Galloway, L. M.; Stodden, R. A.; Akuna, J.; Bruno, B.

    2005-12-01

    In antiquity, the first people to step foot on what are now known as the Hawaiian islands skillfully traversed the Pacific Ocean using celestial navigation and learned observations of scientific phenomena. Long before the Western world ventured beyond the horizon, Hawaiians had invented the chronometer, built aqueduct systems (awai) that continue to amaze modern engineers, and had preventive health systems as well as a comprehensive knowledge of medicinal plants (including antivirals) which only now are working their way through trials for use in modern pharmacopia. Yet, today, Native Hawaiians are severely underrepresented in science-related fields, reflecting (in part) a failure of the Western educational system to nurture the potential of these resourceful students, particularly the many "at-risk" students who are presently over-represented in special education. A curriculum which draws from and incorporates traditional Hawaiian values and knowledge is needed to reinforce links to the inquiry process which nurtured creative thinking during the renaissance of Polynesian history. The primary goal of the Ka Hana `Imi Na`auao Project (translation: `science` or `work in which you seek enlightenment, knowledge or wisdom`) is to increase the number of Native Hawaiian adults in science-related postsecondary education and employment fields. Working closely with Native Hawaiian cultural experts and our high school partners, we will develop and implement a culturally responsive 11th and 12th grade high school science curriculum, infused with math, literacy and technology readiness skills. Software and assistive technology will be used to adapt instruction to individual learners` reading levels, specific disabilities and learning styles. To ease the transition from secondary to post-secondary education, selected grade 12 students will participate in planned project activities that link high school experiences with college science-related programs of study. Ka Hana `Imi Na

  3. Improving leadership training at the United States Naval Academy by utilizing Interactive Multimedia Instruction (IMI)

    OpenAIRE

    Kawane, Shannon E.

    1999-01-01

    This thesis addresses several issues identified in the analysis and design phases of the Instructional Systems Development process to develop an IMI leadership program for the Naval Academy. The overarching goal is to provide the Naval Academy with a study that uses current research and existing innovative leadership programs to answer questions that need to be resolved in developing a program consistent with the Naval Academy's leadership training philosophy. The results suggest that an IMI ...

  4. A strain-, cow-, and herd-specific bio-economic simulation model of intramammary infections in dairy cattle herds.

    Science.gov (United States)

    Gussmann, Maya; Kirkeby, Carsten; Græsbøll, Kaare; Farre, Michael; Halasa, Tariq

    2018-07-14

    Intramammary infections (IMI) in dairy cattle lead to economic losses for farmers, both through reduced milk production and disease control measures. We present the first strain-, cow- and herd-specific bio-economic simulation model of intramammary infections in a dairy cattle herd. The model can be used to investigate the cost-effectiveness of different prevention and control strategies against IMI. The objective of this study was to describe a transmission framework, which simulates spread of IMI causing pathogens through different transmission modes. These include the traditional contagious and environmental spread and a new opportunistic transmission mode. In addition, the within-herd transmission dynamics of IMI causing pathogens were studied. Sensitivity analysis was conducted to investigate the influence of input parameters on model predictions. The results show that the model is able to represent various within-herd levels of IMI prevalence, depending on the simulated pathogens and their parameter settings. The parameters can be adjusted to include different combinations of IMI causing pathogens at different prevalence levels, representing herd-specific situations. The model is most sensitive to varying the transmission rate parameters and the strain-specific recovery rates from IMI. It can be used for investigating both short term operational and long term strategic decisions for the prevention and control of IMI in dairy cattle herds. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Newly identified protein Imi1 affects mitochondrial integrity and glutathione homeostasis in Saccharomyces cerevisiae.

    Science.gov (United States)

    Kowalec, Piotr; Grynberg, Marcin; Pająk, Beata; Socha, Anna; Winiarska, Katarzyna; Fronk, Jan; Kurlandzka, Anna

    2015-09-01

    Glutathione homeostasis is crucial for cell functioning. We describe a novel Imi1 protein of Saccharomyces cerevisiae affecting mitochondrial integrity and involved in controlling glutathione level. Imi1 is cytoplasmic and, except for its N-terminal Flo11 domain, has a distinct solenoid structure. A lack of Imi1 leads to mitochondrial lesions comprising aberrant morphology of cristae and multifarious mtDNA rearrangements and impaired respiration. The mitochondrial malfunctioning is coupled to significantly decrease the level of intracellular reduced glutathione without affecting oxidized glutathione, which decreases the reduced/oxidized glutathione ratio. These defects are accompanied by decreased cadmium sensitivity and increased phytochelatin-2 level. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  6. Hemopoietic stem and precursor cell analysis in umbilical cord blood using the Sysmex SE-9000 IMI channel

    NARCIS (Netherlands)

    Kraai, R; Reymer, AGF; Brouwer-Mandema, GG; van Beckhoven, JM; Hoogeboom, M; le Cessie, S; Kluin-Nelemans, J.C.

    2001-01-01

    Circulating hematopoietic progenitor cells (HPCs) are routinely measured by flow cytometry using CD34 expression. As an alternative, the "immature information" (IMI) channel measurement of the automated hematology analyzer Sysmex SE machines was developed. We tested the IMI channel HPC method with

  7. Current state and further developments in IMIS/KOALA of BFS; Stand und weiteres Vorgehen der IMIS/KOALA Entwicklungen des BFS

    Energy Technology Data Exchange (ETDEWEB)

    Hoebler, C.; Gerich, B.; Stanko, M.; Harms, W. [Bundesamt fuer Strahlenschutz, Salzgitter (Germany)

    2014-01-20

    Several years ago the planning started to completely rework the ''Integrated Measuring and Information System'' IMIS in the BfS entirely. Aim of this as KOALA called development is to build up a new IMIS gradually in modular 4-layers software architecture from very simple, interchangeable and open-source modules. These are connected by standardised interfaces with each other. A high availability as well as intuitive, web-based operability should be guaranteed by a robust IT implementation. All emergency response systems should be brought together symbiotically by the multiple use of components in the BfS in this architecture. The present state as well as the planning for the other action by this development is described and the first results are shown.

  8. Geographic information processing in the Integrated Measuring and Information System (IMIS). An overview; Geographische Informationsverarbeitung im integrierten Mess- und Informationssystem (IMIS). Ein Ueberblick

    Energy Technology Data Exchange (ETDEWEB)

    Burbeck, S. [Bundesamt fuer Strahlenschutz (BfS), Freiburg (Germany)

    2014-01-20

    As most public administrations the Federal Office for Radiation Protection faces various tasks and requirements with geographic information playing an important role. All the more this is true for the Department of Emergency Protection with its Integrated Measuring and Information System (IMIS) and the tasks of information provision for the public. Crucial part in geographic information extraction and provision is cartographic representation. In BfS the different requirements shall be met by a common software architecture, based on web services.

  9. General administrative regulation relating to the Integrated Monitoring and Information System (IMIS) and its application in compliance with the Preventive Radiation Protection Act (StrlSchVG), (AVV-IMIS). As of 27 September 1995

    International Nuclear Information System (INIS)

    1995-01-01

    This general administrative regulation applies to the measuring, communication, compilation, processing, and documentation of data recorded within the IMIS system for the purpose of environmental radioactivity monitoring. (orig./HP) [de

  10. Electric properties and fabrication of IMI-O LB films containing the imidazole group

    CERN Document Server

    Yoo, S Y; Kwon, Y S; Park, J C

    1999-01-01

    We fabricated an IMI-O polymer containing an imidazole group that could form a complex structure between the monolayer and the metal ions at the air-water interface. Also, the monolayer behavior at the air-water interface and the electrical properties of metal-complexed Langmuir-Blodgett (LB) films were investigated by using Brewster angle microscopy (BAM) and current-voltage(I-V) measurements. The difference in the BAM images between the pure water and the aqueous metal ions is attributed to the interactions of the copolymers with the metal ions at the interface and the consequent change of the monolayer organization. In the I-V characteristics, the current for LB films with different metal ion depended on the quantity of the metal-ion complexed with the LB film due to the interaction between the metal ion and the IMI-O polymer.

  11. IMIS, an integrated measuring and information system for environmental radioactivity monitoring

    International Nuclear Information System (INIS)

    Dornstetter, P.; Sell, J.; Schumacher, H.; Helms, D.

    1989-01-01

    The IMIS project system consists of a nationwide information network of interlinked data processing systems installed at 38 regional measuring stations, 11 regional data collecting centres, 5 key stations of the Federal German measuring network, 7 supervisory stations on Federal level, of the BMU, BMVg, and one central Federal office. The systems are equipped with VAX computers using the Ultric operating system and the ORACLE data base system. (DG) [de

  12. National rural drinking water monitoring: progress and challenges with India's IMIS database

    OpenAIRE

    Wescoat, James; Fletcher, Sarah Marie; Novellino, Marianna

    2015-01-01

    National drinking water programs seek to address monitoring challenges that include self-reporting, data sampling, data consistency and quality, and sufficient frequency to assess the sustainability of water systems. India stands out for its comprehensive rural water database known as Integrated Management Information System (IMIS), which conducts annual monitoring of drinking water coverage, water quality, and related program components from the habitation level to the district, state, and n...

  13. IMIS desktop & smartphone software solutions for monitoring spacecrafts' payload from anywhere

    Science.gov (United States)

    Baroukh, J.; Queyrut, O.; Airaud, J.

    In the past years, the demand for satellite remote operations has increased guided by on one hand, the will to reduce operations cost (on-call operators out of business hours), and on the other hand, the development of cooperation space missions resulting in a world wide distribution of engineers and science team members. Only a few off-the-shelf solutions exist to fulfill the need of remote payload monitoring, and they mainly use proprietary devices. The recent advent of mobile technologies (laptops, smartphones and tablets) as well as the worldwide deployment of broadband networks (3G, Wi-Fi hotspots), has opened up a technical window that brings new options. As part of the Mars Science Laboratory (MSL) mission, the Centre National D'Etudes Spatiales (CNES, the French space agency) has developed a new software solution for monitoring spacecraft payloads. The Instrument Monitoring Interactive Software (IMIS) offers state-of-the-art operational features for payload monitoring, and can be accessed remotely. It was conceived as a generic tool that can be used for heterogeneous payloads and missions. IMIS was designed as a classical client/server architecture. The server is hosted at CNES and acts as a data provider while two different kinds of clients are available depending on the level of mobility required. The first one is a rich client application, built on Eclipse framework, which can be installed on usual operating systems and communicates with the server through the Internet. The second one is a smartphone application for any Android platform, connected to the server thanks to the mobile broadband network or a Wi-Fi connection. This second client is mainly devoted to on-call operations and thus only contains a subset of the IMIS functionalities. This paper describes the operational context, including security aspects, that led IMIS development, presents the selected software architecture and details the various features of both clients: the desktop and the sm

  14. IMIS (Integrated Measurement and Information System) - the German integrated radioactivity information and decision support system

    International Nuclear Information System (INIS)

    Weiss, W.; Leeb, H.

    1993-01-01

    IMIS is being set up as part of the German Government's National Response Plan for dealing with the consequences of a large scale radioactive contamination of the environment. The IMIS system has three operational action levels. Level 3 covers the collection of radiological data from state-of-the-art monitoring networks and measurement laboratories. Level 2 involves computerised data processing and quality control, based on standardised procedures for the collection and presentation of measurements. This level also includes the use of transport and dose assessment models. Level 1 includes evaluation of the data, management of the consequences of a given situation, legal enforcement of protective measures and provision of information to the public. In its final form the IMIS system will consist of a total of 75 RISC computers linked together by an efficient packet-switched Wide Area Network. Owing to various demands of the individual users, three different types of RISC computers are used. The system software includes ULTRIX, TCP/IP and X windows. The relational database management system ORACLE is used together with the query language SQL-Plus. Statistical analyses are carried out with the standard product SAS. The geographical information system TERRA provides all the tools necessary for a detailed geographic presentation of the data. (author)

  15. SD card projects using the PIC microcontroller

    CERN Document Server

    Ibrahim, Dogan

    2010-01-01

    PIC Microcontrollers are a favorite in industry and with hobbyists. These microcontrollers are versatile, simple, and low cost making them perfect for many different applications. The 8-bit PIC is widely used in consumer electronic goods, office automation, and personal projects. Author, Dogan Ibrahim, author of several PIC books has now written a book using the PIC18 family of microcontrollers to create projects with SD cards. This book is ideal for those practicing engineers, advanced students, and PIC enthusiasts that want to incorporate SD Cards into their devices. SD cards are che

  16. A strain-, cow-, and herd-speciÞc bio-economic simulation model of intramammary infections in dairy cattle herds

    DEFF Research Database (Denmark)

    Gussmann, Maya Katrin; Kirkeby, Carsten Thure; Græsbøll, Kaare

    2018-01-01

    Intramammary infections (IMI) in dairy cattle lead to economic losses for farmers, both through reduced milk production and disease control measures. We present the first strain-, cow- and herd-specific bio-economic simulation model of intramammary infections in a dairy cattle herd. The model can...... various within-herd levels of IMI prevalence, depending on the simulated pathogens and their parameter settings. The parameters can be adjusted to include different combinations of IMI causing pathogens at different prevalence levels, representing herd-specific situations. The model is most sensitive...

  17. G eobacter sp. SD-1 with enhanced electrochemical activity in high-salt concentration solutions

    KAUST Repository

    Sun, Dan; Call, Douglas; Wang, Aijie; Cheng, Shaoan; Logan, Bruce E.

    2014-01-01

    © 2014 Society for Applied Microbiology and John Wiley & Sons Ltd. Summary: An isolate, designated strain SD-1, was obtained from a biofilm dominated by Geobacter sulfurreducens in a microbial fuel cell. The electrochemical activity of strain SD-1 was compared with type strains, G.sulfurreducensPCA and Geobacter metallireducensGS-15, and a mixed culture in microbial electrolysis cells. SD-1 produced a maximum current density of 290±29Am-3 in a high-concentration phosphate buffer solution (PBS-H, 200mM). This current density was significantly higher than that produced by the mixed culture (189±44Am-3) or the type strains (<70Am-3). In a highly saline water (SW; 50mM PBS and 650mM NaCl), current by SD-1 (158±4Am-3) was reduced by 28% compared with 50mM PBS (220±4Am-3), but it was still higher than that of the mixed culture (147±19Am-3), and strains PCA and GS-15 did not produce any current. Electrochemical tests showed that the improved performance of SD-1 was due to its lower charge transfer resistance and more negative potentials produced at higher current densities. These results show that the electrochemical activity of SD-1 was significantly different than other Geobacter strains and mixed cultures in terms of its salt tolerance.

  18. G eobacter sp. SD-1 with enhanced electrochemical activity in high-salt concentration solutions

    KAUST Repository

    Sun, Dan

    2014-07-16

    © 2014 Society for Applied Microbiology and John Wiley & Sons Ltd. Summary: An isolate, designated strain SD-1, was obtained from a biofilm dominated by Geobacter sulfurreducens in a microbial fuel cell. The electrochemical activity of strain SD-1 was compared with type strains, G.sulfurreducensPCA and Geobacter metallireducensGS-15, and a mixed culture in microbial electrolysis cells. SD-1 produced a maximum current density of 290±29Am-3 in a high-concentration phosphate buffer solution (PBS-H, 200mM). This current density was significantly higher than that produced by the mixed culture (189±44Am-3) or the type strains (<70Am-3). In a highly saline water (SW; 50mM PBS and 650mM NaCl), current by SD-1 (158±4Am-3) was reduced by 28% compared with 50mM PBS (220±4Am-3), but it was still higher than that of the mixed culture (147±19Am-3), and strains PCA and GS-15 did not produce any current. Electrochemical tests showed that the improved performance of SD-1 was due to its lower charge transfer resistance and more negative potentials produced at higher current densities. These results show that the electrochemical activity of SD-1 was significantly different than other Geobacter strains and mixed cultures in terms of its salt tolerance.

  19. Marketingový audit IMI Hydronic Engineering pro český trh

    OpenAIRE

    Drápelová, Zuzana

    2014-01-01

    The main objective of this thesis is to execute a marketing audit of IMI Hydronic Engineering at the Czech market in order to identify problem areas and opportunities, define key performance indicators (KPI) and follow recommended procedures to improve marketing performance of this company and increase the efficiency of the company as a whole. Marketing audit is a comprehensive analysis of the company and its surroundings, which does not contain only simple analysis of the current situation o...

  20. Imi Hale – The Native Hawaiian Cancer Awareness, Research, and Training Network: Second-Year Status Report

    Science.gov (United States)

    Braun, Kathryn L.; Tsark, JoAnn; Ann Santos, Lorrie; Abrigo, Lehua

    2010-01-01

    Purpose The purpose of this paper is to describe ‘Imi Hale, a program developed and managed by Native Hawaiians to increase cancer awareness and research capacity among Native Hawaiians. This US subgroup of indigenous people of the Hawaiian islands has disproportionately high rates of cancer mortality and low rates of participation in health and research careers. Methods As a community-based research project, ‘Imi Hale spent its first year gathering data from Native Hawaiians about their cancer awareness and research priorities. These findings guide ‘Imi Hale’s community and scientific advisors, a community-based Institutional Review Board, Na Liko Noelo (budding researchers), and staff in developing and carrying out projects that address these priority areas. Emphasis is placed on transferring skills and resources to Native Hawaiians through training, technical assistance, and mentorship. A biennial survey assesses the extent to which community-based participatory research principles are being followed. Principal Findings By the end of the second year, statewide and island-specific awareness plans were produced, and 9 funded awareness projects are supporting the development and dissemination of Hawaiian health education materials. Research accomplishments include the enrollment of 42 Native Hawaiian Na Liko Noelo (budding researchers), 22 of which are involved in 14 funded research projects. The biennial evaluation survey found that 92% of our advisors felt that ‘Imi Hale was promoting scientifically rigorous research that was culturally appropriate and respectful of Native Hawaiian beliefs, and 96% felt that ‘Imi Hale was following its own principles of community-based participatory research. Conclusion ‘Imi Hale’s community-based approach to promoting cancer awareness will result in a sustainable infrastructure for reducing the cancer burden on Native Hawaiians. PMID:15352771

  1. The Inner Magnetospheric Imager (IMI): Instrument heritage and orbit viewing analysis

    Science.gov (United States)

    Wilson, Gordon R.

    1992-12-01

    For the last two years an engineering team in the Program Development Office at MSFC has been doing design studies for the proposed Inner Magnetospheric Imager (IMI) mission. This team had a need for more information about the instruments that this mission would carry so that they could get a better handle on instrument volume, mass, power, and telemetry needs as well as information to help assess the possible cost of such instruments and what technology development they would need. To get this information, an extensive literature search was conducted as well as interviews with several members of the IMI science working group. The results of this heritage survey are summarized below. There was also a need to evaluate the orbits proposed for this mission from the stand point of their suitability for viewing the various magnetospheric features that are planned for this mission. This was accomplished by first, identifying the factors which need to be considered in selecting an orbit, second, translating these considerations into specific criteria, and third, evaluating the proposed orbits against these criteria. The specifics of these criteria and the results of the orbit analysis are contained in the last section of this report.

  2. Understanding Nuclei in the upper sd - shell

    OpenAIRE

    Sarkar, M. Saha; Bisoi, Abhijit; Ray, Sudatta; Kshetri, Ritesh; Sarkar, S.

    2013-01-01

    Nuclei in the upper-$sd$ shell usually exhibit characteristics of spherical single particle excitations. In the recent years, employment of sophisticated techniques of gamma spectroscopy has led to observation of high spin states of several nuclei near A$\\simeq$ 40. In a few of them multiparticle, multihole rotational states coexist with states of single particle nature. We have studied a few nuclei in this mass region experimentally, using various campaigns of the Indian National Gamma Array...

  3. The documentation of readiness of the Landesamt of environmental protection of Saxony-Anhalt in case of intensive measuring program of IMIS. Pretension and reality; Die Einsatzdokumentation des Landesamtes fuer Umweltschutz Sachsen-Anhalt zum IMIS-Intensivmessprogramm. Anspruch und Wirklichkeit

    Energy Technology Data Exchange (ETDEWEB)

    Haensel, F. [Landesamt fuer Umweltschutz Sachsen-Anhalt, Halle/Saale (Germany)

    2014-01-20

    The documentation of readiness of the Landesamt of environmental protection of Saxony-Anhalt for the IMIS intensive measuring program was worked out since 2001 not only for preparing national and international exercises but also in the case of an accidental contamination of the environment. This documentation contains practical and organizational references for alarm, sampling, sample preparation and analytical tests in case of intensive measuring program of IMIS. The IMIS exercise in the autumn 2012 has shown the fitness of this documentation in the practice. The laboratories for environmental radioactivity of Saxony-Anhalt should be able to meet all requirements of an intensive measuring program of IMIS.

  4. Are sdAs helium core stars?

    Directory of Open Access Journals (Sweden)

    Pelisoli Ingrid

    2017-12-01

    Full Text Available Evolved stars with a helium core can be formed by non-conservative mass exchange interaction with a companion or by strong mass loss. Their masses are smaller than 0.5 M⊙. In the database of the Sloan Digital Sky Survey (SDSS, there are several thousand stars which were classified by the pipeline as dwarf O, B and A stars. Considering the lifetimes of these classes on the main sequence, and their distance modulus at the SDSS bright saturation, if these were common main sequence stars, there would be a considerable population of young stars very far from the galactic disk. Their spectra are dominated by Balmer lines which suggest effective temperatures around 8 000-10 000 K. Several thousand have significant proper motions, indicative of distances smaller than 1 kpc. Many show surface gravity in intermediate values between main sequence and white dwarf, 4.75 < log g < 6.5, hence they have been called sdA stars. Their physical nature and evolutionary history remains a puzzle. We propose they are not H-core main sequence stars, but helium core stars and the outcomes of binary evolution. We report the discovery of two new extremely-low mass white dwarfs among the sdAs to support this statement.

  5. An example of technological transfer to industry: the 'IMI' project

    Energy Technology Data Exchange (ETDEWEB)

    Stefanini, A.; Amendolia, S.R.; Annovazzi, A.; Baldelli, P.; Bigongiari, A.; Bisogni, M.G.; Catarsi, F.; Cetronio, A.; Chianella, M.; Cinti, M.N.; Delogu, P.; Fantacci, M.E.; Galimberti, D.; Gambaccini, M.; Gilardoni, C.; Iurlaro, G.; Lanzieri, C.; Meoni, M.; Novelli, M.; Pani, R.; Passuello, G.; Pellegrini, R.; Pieracci, M.; Quattrocchi, M.; Rosso, V. E-mail: valeria.rosso@pi.infn.it; Venturelli, L

    2004-02-01

    Several INFN Sections and Departments of Physics of Italian Universities have spent many man-years in the attempt to adapt detector and read-out technologies, originally developed in the field of High Energy Physics, to the domain of biomedical apparatuses. The research covered such areas as the exploitation of crystals for the production of monochromatic X-ray beams, the development of devices for efficient X-ray detection, the design of advanced VLSI electronics, the improvement of Position Sensitive Photomultiplier Tubes and crystals for Nuclear Medicine gamma-cameras. These studies have been integrated in the Integrated Mammographic Imaging (IMI) project, funded by the Italian Government through the law 46/82 (art.10) and is carried on by five high-technology industries in Italy, namely LABEN, CAEN, AMS, GILARDONI and POL.HI.TECH. We report on the status of this technological transfer project.

  6. Enterobacter cloacae Complex Isolates Harboring blaNMC-A or blaIMI-Type Class A Carbapenemase Genes on Novel Chromosomal Integrative Elements and Plasmids.

    Science.gov (United States)

    Boyd, David A; Mataseje, Laura F; Davidson, Ross; Delport, Johannes A; Fuller, Jeff; Hoang, Linda; Lefebvre, Brigitte; Levett, Paul N; Roscoe, Diane L; Willey, Barbara M; Mulvey, Michael R

    2017-05-01

    Carbapenem-resistant Enterobacter cloacae complex isolates submitted to a reference laboratory from 2010 to 2015 were screened by PCR for seven common carbapenemase gene groups, namely, KPC, NDM, OXA-48, VIM, IMP, GES, and NMC-A/IMI. Nineteen of the submitted isolates (1.7%) were found to harbor Ambler class A bla NMC-A or bla IMI -type carbapenemases. All 19 isolates were resistant to at least one carbapenem but susceptible to aminoglycosides, trimethoprim-sulfamethoxazole, tigecycline, and ciprofloxacin. Most isolates (17/19) gave positive results with the Carba-NP test for phenotypic carbapenemase detection. Isolates were genetically diverse by pulsed-field gel electrophoresis macrorestriction analysis, multilocus sequence typing, and hsp60 gene analysis. The genes were found in various Enterobacter cloacae complex species; however, bla NMC-A was highly associated with Enterobacter ludwigii Whole-genome sequencing and bioinformatics analysis revealed that all NMC-A ( n = 10), IMI-1 ( n = 5), and IMI-9 ( n = 2) producers harbored the carbapenemase gene on EludIMEX-1-like integrative mobile elements (EcloIMEXs) located in the identical chromosomal locus. Two novel genes, bla IMI-5 and bla IMI-6 , were harbored on different IncFII-type plasmids. Enterobacter cloacae complex isolates harboring bla NMC-A/IMI -type carbapenemases are relatively rare in Canada. Though mostly found integrated into the chromosome, some variants are located on plasmids that may enhance their mobility potential. © Crown copyright 2017.

  7. Understanding nuclei in the upper sd - shell

    Energy Technology Data Exchange (ETDEWEB)

    Sarkar, M. Saha; Bisoi, Abhijit; Ray, Sudatta [Nuclear Physics Division, Saha Institute of Nuclear Physics, Kolkata 700064 (India); Kshetri, Ritesh [Nuclear Physics Division, Saha Institute of Nuclear Physics, Kolkata 700064, India and Sidho-Kanho-Birsha University, Purulia - 723101 (India); Sarkar, S. [Indian Institute of Engineering Science and Technology, Shibpur, Howrah - 711103 (India)

    2014-08-14

    Nuclei in the upper-sd shell usually exhibit characteristics of spherical single particle excitations. In the recent years, employment of sophisticated techniques of gamma spectroscopy has led to observation of high spin states of several nuclei near A ≃ 40. In a few of them multiparticle, multihole rotational states coexist with states of single particle nature. We have studied a few nuclei in this mass region experimentally, using various campaigns of the Indian National Gamma Array setup. We have compared and combined our empirical observations with the large-scale shell model results to interpret the structure of these nuclei. Indication of population of states of large deformation has been found in our data. This gives us an opportunity to investigate the interplay of single particle and collective degrees of freedom in this mass region.

  8. Isospin symmetry breaking in sd shell nuclei

    International Nuclear Information System (INIS)

    Lam, Y.W.

    2011-12-01

    In the thesis, we develop a microscopic approach to describe the isospin-symmetry breaking effects in sd-shell nuclei. The work is performed within the nuclear shell model. A realistic isospin-conserving Hamiltonian is perfected by a charge-dependent part consisting of the Coulomb interaction and Yukawa-type meson exchange potentials to model charge-dependent forces of nuclear origin. The extended database of the experimental isobaric mass multiplet equation coefficients was compiled during the thesis work and has been used in a fit of the Hamiltonian parameters. The constructed Hamiltonian provides an accurate theoretical description of the isospin mixing nuclear states. A specific behaviour of the IMME (Isobaric Multiplet Mass Equation) coefficients have been revealed. We present two important applications: (i) calculations of isospin-forbidden proton emission amplitudes, which is often of interest for nuclear astrophysics, and (ii) calculation on corrections to nuclear Fermi beta decay, which is crucial for the tests of fundamental symmetries of the weak interaction. (author)

  9. Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib

    DEFF Research Database (Denmark)

    Kumar, S K; Lee, JH; Lahuerta, J J

    2012-01-01

    with relapsed MM, who were refractory to bortezomib and were relapsed following, refractory to or ineligible to receive, an IMiD (immunomodulatory drug), had measurable disease, and ECOG PS of 0, 1 or 2. The date patients satisfied the entry criteria was defined as time zero (T(0)). The median age at diagnosis...... was 58 years, and time from diagnosis to T(0) was 3.3 years. Following T(0), 213 (74%) patients had a treatment recorded with one or more regimens (median=1; range 0-8). The first regimen contained bortezomib in 55 (26%) patients and an IMiD in 70 (33%). A minor response or better was seen to at least...

  10. Final report of the safety assessment of Alcohol Denat., including SD Alcohol 3-A, SD Alcohol 30, SD Alcohol 39, SD Alcohol 39-B, SD Alcohol 39-C, SD Alcohol 40, SD Alcohol 40-B, and SD Alcohol 40-C, and the denaturants, Quassin, Brucine Sulfate/Brucine, and Denatonium Benzoate.

    Science.gov (United States)

    2008-01-01

    Alcohol Denat. is the generic term used by the cosmetics industry to describe denatured alcohol. Alcohol Denat. and various specially denatured (SD) alcohols are used as cosmetic ingredients in a wide variety of products. Many denaturants have been previously considered, on an individual basis, as cosmetic ingredients by the Cosmetic Ingredient Review (CIR) Expert Panel, whereas others, including Brucine and Brucine Sulfate, Denatonium Benzoate, and Quassin, have not previously been evaluated. Quassin is a bitter alkaloid obtained from the wood of Quassia amara. Quassin has been used as an insect antifeedant and insecticide and several studies demonstrate its effectiveness. At oral doses up to 1000 mg/kg using rats, Quassin was not toxic in acute and short-term tests, but some reversible piloerection, decrease in motor activity, and a partial loss of righting reflex were found in mice at 500 mg/kg. At 1000 mg/kg given intraperitoneally (i.p.), all mice died within 24 h of receiving treatment. In a cytotoxicity test with brine shrimp, 1 mg/ml of Quassin did not possess any cytotoxic or antiplasmodial activity. Quassin administered to rat Leydig cells in vitro at concentrations of 5-25 ng/ml inhibited both the basal and luteinizing hormone (LH)-stimulated testosterone secretion in a dose-related fashion. Quassin at doses up to 2.0 g/kg in drinking water using rats produced no significant effect on the body weights, but the mean weights of the testes, seminal vesicles, and epididymides were significantly reduced, and the weights of the anterior pituitary glands were significantly increased. The sperm counts and levels of LH, follicle-stimulating hormone (FSH), and testosterone were significantly lower in groups treated with Quassin. Brucine is a derivative of 2-hydroxystrychnine. Swiss-Webster mice given Brucine base, 30 ml/kg, had an acute oral LD(50) of 150 mg/kg, with central nervous system depression followed by convulsions and seizures in some cases. In those

  11. Buzağılarda Preruminant Dönem Beslenmesinin Rumen Gelişimi Üzerine Etkisi

    OpenAIRE

    Gümüş, Erinç

    2018-01-01

    Beslenme, hızlı gelişen ve yüksek verime sahip hayvanların elde edilmesinde genetik faktörler kadar önem taşımaktadır. Buzağılarda, özellikle sütten kesim öncesinde sağlıklı bir rumen gelişimi sağlamak, hem kuru yem tüketimine geçişi hızlandırarak maliyeti azaltmada, hem de fizyolojik gelişimi hızlandırmada fayda sağlamaktadır. Buzağıların sütten kesim öncesi beslenmesinde katı gıdalar rumen gelişimi açısından büyük öneme sahiptir. Yapılan çalışmalarda konsantre yemlerin içerdikleri bütirik v...

  12. MASALAH MOTIVASI BELAJAR SISWA SD PADA IPS

    Directory of Open Access Journals (Sweden)

    Erlisnawati Erlisnawati

    2016-09-01

    Full Text Available Masalah Motivasi Siswa SD pada ilmu pengetahuan Sosial. Motivasi adalah hal yang sangat penting yang mempengaruhi kegiatan / pekerjaan yang dilakukan oleh individu, termasuk yang mempengaruhi siswa dalam kegiatan belajar. Motivasi adalah salah satu elemen yang paling penting dalam pengajaran yang efektif. Pembelajaran diikuti oleh siswa yang termotivasi untuk menjadi benar-benar menyenangkan, terutama untuk guru. Siswa termotivasi untuk belajar sesuatu akan menggunakan proses kognitif yang lebih tinggi belajar dan menyerap dan mengingat lebih dari itu. Motivasi sebagai proses internal yang memungkinkan, membimbing dan mempertahankan perilaku dari waktu ke waktu. Ada beberapa teori motivasi yaitu: teori perilaku, teori kebutuhan, teori atribusi, teori belajar mandiri dan teori harapan. Motivasi dipengaruhi oleh faktor intrinsik dan faktor ekstinsik. Guru harus mengetahui kondisi ketika siswa termotivasi dan ketika kondisi siswa tidak termotivasi. Untuk itu seorang guru harus memiliki kemampuan untuk memotivasi siswa. Adapun cara yang bisa dilakukan untuk memotivasi guru untuk meningkatkan siswa adalah untuk membangkitkan minat, menjaga rasa ingin tahu, menggunakan berbagai cara yang menarik menyajikan, membantu siswa menentukan target mereka sendiri. Pembelajaran yang dilakukan oleh siswa dengan mitivasi tinggi akan menciptakan proses pembelajaran yang efektif.Kata kunci: masalah, motivasi, ilmu pengetahuan sosial, sekolah dasarMotivation is a very important thing that affects the activities / work performed by the individual, including that affect students in learning activities. Motivation is one of the most important elements in effective teaching. Learning followed by students who are motivated to be really fun, especially for teachers. Students are motivated to learn something will use higher cognitive processes learn and absorb and remember more of it. Motivation as internal processes that enable, guide and sustain behavior over time. There

  13. Design of a forging processing route for a gas turbine compressor disc in IMI 834

    International Nuclear Information System (INIS)

    Clark, G.S.

    1993-01-01

    The microstructure in all parts of a modern gas turbine compressor disc must be carefully controlled to give the optimum balance for resistance to creep and fatigue. This is particularly true for advanced titanium alloys such as IMI834. Dynamic recrystallisation during high temperature deformation and static recrystallisation and grain growth during heat treatment, all have a profound effect on the grain structure of the disc. These processes are affected by temperature, rate of deformation and various microstructural features. These may include the size and volume fraction of primary alpha particles and current beta grain size. The construction of a computer model to simulate the forging process must therefore take all these factors into account to fully simulate the mechanical and microstructural behaviour of the material during processing. This requires a complete characterisation of the material to formulate mechanical and microstructural constitutive equations for use in a visco-plastic finite element forging model. Similarly the forging equipment must be fully characterised so that forging processes can be accurately simulated. (orig.)

  14. SD-PAMs: What, Where, When and How?

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This paper examines what ''sustainable development policies and measures'' (SD-PAMs) could be, and how they could be implemented and could fit into a post-2012 climate regime. This paper assumes that the option to implement SD-PAMs instead of quantified GHG emission commitments post-2012 is an option that would be likely to be only open to non-Annex I countries. There are several key, but unanswered, questions related to SD-PAMs. These include policy-related issues such as which countries could take on commitments to implement SD-PAMs (rather than quantified emission commitments)? Why would particular countries decide to take on such commitments? They also include questions related to how SD-PAMs could be implemented. For many other options for possible post-2012 GHG mitigation actions, including by non-Annex I countries, have also been proposed. However, this paper focuses solely on SD-PAMs.

  15. How Changes in Anti-SD Sequences Would Affect SD Sequences in Escherichia coli and Bacillus subtilis.

    Science.gov (United States)

    Abolbaghaei, Akram; Silke, Jordan R; Xia, Xuhua

    2017-05-05

    The 3' end of the small ribosomal RNAs (ssu rRNA) in bacteria is directly involved in the selection and binding of mRNA transcripts during translation initiation via well-documented interactions between a Shine-Dalgarno (SD) sequence located upstream of the initiation codon and an anti-SD (aSD) sequence at the 3' end of the ssu rRNA. Consequently, the 3' end of ssu rRNA (3'TAIL) is strongly conserved among bacterial species because a change in the region may impact the translation of many protein-coding genes. Escherichia coli and Bacillus subtilis differ in their 3' ends of ssu rRNA, being GAUC ACCUCCUUA 3' in E. coli and GAUC ACCUCCUU UCU3' or GAUC ACCUCCUU UCUA3' in B. subtilis Such differences in 3'TAIL lead to species-specific SDs (designated SD Ec for E. coli and SD Bs for B. subtilis ) that can form strong and well-positioned SD/aSD pairing in one species but not in the other. Selection mediated by the species-specific 3'TAIL is expected to favor SD Bs against SD Ec in B. subtilis , but favor SD Ec against SD Bs in E. coli Among well-positioned SDs, SD Ec is used more in E. coli than in B. subtilis , and SD Bs more in B. subtilis than in E. coli Highly expressed genes and genes of high translation efficiency tend to have longer SDs than lowly expressed genes and genes with low translation efficiency in both species, but more so in B. subtilis than in E. coli Both species overuse SDs matching the bolded part of the 3'TAIL shown above. The 3'TAIL difference contributes to the host specificity of phages. Copyright © 2017 Abolbaghaei et al.

  16. Türk İstihbaratının Tarihsel Gelişimi

    Directory of Open Access Journals (Sweden)

    Eray GÖÇ

    2013-09-01

    Full Text Available Bu çalışmanın amacı, Türk istihbaratının Osmanlı’nın özellikle son dönemlerinden günümüze tarihsel gelişimi hakkında bilgi vermektir. Tarih sahnesinde istihbarat örgütlerinin üstlendikleri rolleri Türk siyasi hayatına etkilerini araştırmış, günümüz toplum yapısının oluşmasında üstlendikleri roller hakkında bilgi vermiştir. Çalışma Osmanlıda hafiye teşkilatı ile başlayıp, İttihat ve Terakki, MAH, JİTEM, ÖHD ve MİT ile devam eden bir silsilenin Anadolu toprakları üzerinden 100 yılı devirmiş etkisine dair bilgiler içermektedir. Kitap, dergi, makale gibi kaynakların yanı sıra konuyla ilgili çeşitli çalışmalar yapmış olan susurluk araştırma komisyonu başkanı Mehmet Elkatmış, AK parti milletvekili Şamil Tayyar ve gazeteci Nasuhi Güngör ile konuyla ilgili yapılan röportaj da çalışmada yer almaktadır. Çalışma bir taraftan da istihbarat örgütlerinin, devlete hukuk çizgisinin dışına çıkma manevrası kazandırdığı sorunsalını irdelemektedir. Devlet, istihbarat örgütleri sayesinde bekası adına hukuk dışılığı ilke edinme gayretine girmiş olabilir mi? Ya da istihbarat örgütleri devlet adına deyip zaman zaman gayri nizami davranışlar sergilemiş midir? Bu sorular irdelenmiştir.

  17. Purification and characterization of bacteriocin produced by oral Lactobacillus paracasei SD1.

    Science.gov (United States)

    Wannun, P; Piwat, S; Teanpaisan, R

    2014-06-01

    The present study aimed to purify and characterize the antimicrobial protein from Lactobacillus paracasei SD1, which is a strain from the human oral cavity. Antimicrobial activity was obtained from purifying the culture supernatant of L. paracasei SD1. Purification of the active compound was achieved with ammonium sulfate precipitation followed by chloroform and gel filtration chromatography. As revealed by SDS-PAGE, the active fraction was homogeneous, showing a protein with an approximate molecular weight of 25,000 Da. It was confirmed as having a molecular mass of 24,028.2 Da by mass spectrometry. The antimicrobial compound, named "paracasin SD1", exhibited a broad spectrum against oral pathogens. Paracasin SD1 was stable in a pH range between 3.0 and 8.0 at 100 °C for 5 min, and showed resistance to α-amylase, catalase, lysozyme and whole saliva. However, its activity was lost after proteinase K and trypsin treatment. The results obtained suggest the possibility of using paracasin SD1 for application in prevention/treatment of oral diseases. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. Kitabın Teknolojik Değişimi

    Directory of Open Access Journals (Sweden)

    Hakan Anameriç

    2014-06-01

    Full Text Available Kitap ilk sayfalarından hatta satırlarından başlayarak papirüs, parşömen tahta veya metal tabakalar üzerine yazılmış, rulo halinde ya da ciltlenmiş olsun iki yönüyle ele alınması gereken bir araç -bilgi taşıyıcısı- olmuştur. Kitap, yazılmış ya da basılmış yaprakların bir araya getirilmesinden oluşan ve bir konuyu belirli bir düzen içinde sunan yapıt olarak tanımlanmaktadır. Kitabı oluşturan bu iki unsur, onun içeriği ve fiziksel yapısıdır. İçerik, anlatılmak istenen konuyu/temayı yani kitabın amacını ifade eder, bilgilendirici, öğretici, yol gösterici, eleştirici olanı aktarır. Bilinen en eski el yazması kitapların günümüzden yaklaşık 3000-3700 yıl öncesine tarihlenen ve Hinduizm’in ilk kutsal metinlerinin yer aldığı Rig Veda[1]dan günümüzün elektronik kitaplarına kadar geçen süreç içerisinde her ne biçimde ve içerikte olsun “kitap” kavramı zihinlerimizde yer etmiştir. Dünyanın neresinde olursa olsun hangi dil ile söylenirse söylensin “kitap” hep aynı fiili ve şekli ifade etmektedir. Günlük yaşantımızın son 30 yılında hemen her alanda bireylerin yaşantısını değiştiren/kolaylaştıran teknoloji, uzun bir geçmişe sahip olan kitap için de pek çok değişimi ortaya koymuştur. Ancak bu değişim kavramlardan, kitabın bileşenlerinden çok ona erişimi, onu üretmeyi/ yazmayı ve ondan faydalanmayı daha keyifli kılmayı amaçlamaktadır. E-kitap ile ilgili son 10 yıl içerisinde başta eğitim olmak üzere, elektronik kaynaklar, kütüphaneler, bilgi hizmetleri, okuma alışkanlığı, iletişim gibi alanlarda çok sayıda akademik ve sosyal çalışmalar yapılmıştır. Bu çalışmada e-kitap teknolojisi ile gündelik yaşamda bireylerin kitap anlayışındaki farklılaşma, görsel ve yazılı basın örnekleri[2] bağlamında farklı bir bakış açısı ile değerlendirilecektir. [1] Hinduizm’in ilk kutsal metinleri olan

  19. Penerapan Model Beyond Centers and Circle Tme SD Kelas Satu

    OpenAIRE

    FITRIA, EVY

    2014-01-01

    Penelitian bertujuan mengkaji pelaksanaan penerapan model pembelajaran Sentra Model pembelajaran sentra (Beyond Centers and Circle Time) dilaksanakan pada siswa kelas satu SD Islam Jayawinata Kota Tangerang 2013. Penelitian menggunakan metode kualitatitf dengan analisis model Miles and Huberman. Hasil penelitian mengungkapkan bahwa kegiatan SD kelas satu menggunakan model pembelajaran sentra atau BCCT pada tahun ajaran baru sehingga guru memiliki panduan ketika membuat rencana pembelajaran; p...

  20. Positional dependence of the SNPP VIIRS SD BRDF degradation factor

    Science.gov (United States)

    Lei, Ning; Chen, Xuexia; Chang, Tiejun; Xiong, Xiaoxiong

    2017-09-01

    The Visible Infrared Imaging Radiometer Suite (VIIRS) aboard the Suomi National Polar-orbiting Partnership (SNPP) satellite is a passive scanning radiometer and an imager. The VIIRS regularly performs on-orbit radiometric calibration of its reflective solar bands (RSBs) through observing an onboard sunlit solar diffuser (SD). The reflectance of the SD changes over time and the change is denoted as the SD bidirectional reflectance distribution function degradation factor. The degradation factor, measured by an onboard solar diffuser stability monitor, has been shown to be both incident sunlight and outgoing direction dependent. In this Proceeding, we investigate the factor's dependence on SD position. We develop a model to relate the SD degradation factor with the amount of solar exposure. We use Earth measurements to evaluate the effectiveness of the model.

  1. In vitro efficacy of teat antiseptics against Staphylococcus aureus strains isolated from bovine mastitis

    Directory of Open Access Journals (Sweden)

    Renata Paoli Santos

    2016-08-01

    Full Text Available The process of teat disinfection is a widely accepted component of successful mastitis control programs by reducing the number of bacteria on the teat skin and healing teat lesions. For contagious pathogens such as Staphylococcus aureus, post-milking teat disinfection remains a simple, effective and economical practice for prevention of new intramammary infections (IMIs of lactating dairy cows. Despite the universal acceptance of teat dipping as a method of mastitis control, variations in the susceptibility and resistance profile of mastitis pathogens among antiseptics have been described. Thus, here we sought to explore the in vitro efficacy of the followings antiseptics against S. aureus isolated from IMIs: chlorhexidine (2.0%, chlorine (2.5%, quarternary ammonium (4.0%, lactic acid (2.0% and iodine (0.6%. We used 50 S. aureus strains isolated from bovine IMIs from 50 dairy herds located at Minas Gerais, São Paulo, Paraná and Rio Grande do Sul States (Brazil. The antiseptics were evaluated at four different specific intervals (15, 30, 60 and 300 s. We found a higher activity for quarternary ammonium and chlorhexidine against S. aureus at all time-points, followed by iodine and then chlorine. Lactic acid treatment produced the worst results for all time-points and strains. Due to variations in the sensitivity and resistance profile of antiseptics against S. aureus isolated from IMIs, the effectiveness of the antiseptics against the major mastitis pathogens should be periodically evaluated in dairy farms in an attempt to reduce the rate of new IMIs in the herd.

  2. EKSISTENSI SD GMIT DI ROTE NDAO (Studi Deskriptif Penempatan Guru PNS pada SD GMIT Rote Ndao-NTT

    Directory of Open Access Journals (Sweden)

    Melki Manafe

    2013-12-01

    berasal dari Negara. Hasil-hasil inimenempatkan SD GMIT di Rote Ndao pada status quasistate school dimana SD GMIT adalah milik GMIT akan tetapi semua operasional (subsidi pendidikan dan sumber daya manusia/guru selalu bergantung pada Negara.

  3. SdAb heterodimer formation using leucine zippers

    Science.gov (United States)

    Goldman, Ellen R.; Anderson, George P.; Brozozog-Lee, P. Audrey; Zabetakis, Dan

    2013-05-01

    Single domain antibodies (sdAb) are variable domains cloned from camel, llama, or shark heavy chain only antibodies, and are among the smallest known naturally derived antigen binding fragments. SdAb derived from immunized llamas are able to bind antigens with high affinity, and most are capable of refolding after heat or chemical denaturation to bind antigen again. We hypothesized that the ability to produce heterodimeric sdAb would enable reagents with the robust characteristics of component sdAb, but with dramatically improved overall affinity through increased avidity. Previously we had constructed multimeric sdAb by genetically linking sdAb that bind non-overlapping epitopes on the toxin, ricin. In this work we explored a more flexible approach; the construction of multivalent binding reagents using multimerization domains. We expressed anti-ricin sdAb that recognize different epitopes on the toxin as fusions with differently charged leucine zippers. When the initially produced homodimers are mixed the leucine zipper domains will pair to produce heterodimers. We used fluorescence resonance energy transfer to confirm heterodimer formation. Surface plasmon resonance, circular dichroism, enzyme linked immunosorbent assays, and fluid array assays were used to characterize the multimer constructs, and evaluate their utility in toxin detection.

  4. Study of sdO models. Pulsation Analysis

    OpenAIRE

    Rodríguez-López, C.; Moya, A.; Garrido, R.; MacDonald, J.; Oreiro, R.; Ulla, A.

    2009-01-01

    We have explored the possibility of driving pulsation modes in models of sdO stars in which the effects of element diffusion, gravitational settling and radiative levitation have been neglected so that the distribution of iron-peak elements remains uniform throughout the evolution. The stability of these models was determined using a non-adiabatic oscillations code. We analysed 27 sdO models from 16 different evolutionary sequences and discovered the first ever sdO models capable of driving h...

  5. UTVÄRDERING AV UTVALDA SD-WAN PRODUKTER

    OpenAIRE

    Åkerblom, Jacob

    2016-01-01

    Denna jämförelsestudie ämnar att undersöka marknadens leverantörer av nätverksutrustning de- finierade som Software Defined Wide Area Networks(SD-WAN). SD-WAN är en innovativ teknik som applicerar virtualisering och Software defined networking koncept i Wide Area Networks (WAN) för att skapa kostnadseffektiva nätverk. Studien har utförts på företaget Curitiba som idag arbetar med konsulttjänster inom utvalda WAN-optimering och SD-WAN-produkter. Arbetets syfte är att utvärdera SD-WAN-lösningar...

  6. Biota - 2011 Vegetation Inventory - Mud Lake, MN/SD

    Data.gov (United States)

    Army Corps of Engineers, Department of the Army, Department of Defense — 2011 Vegetation Classification for Mud Lake, MN/SD Vegetation Project Report, OMBIL Environmental Stewardship - Level 1 Inventory. Mud Lake, located on the Minnesota...

  7. Impact of methodological choices on findings from pharmacoepidemiological studies: Final results of the IMI-protect (pharmacoepidemiological research on outcomes of therapeutics by a European consortium) project

    NARCIS (Netherlands)

    Klungel, Olaf; De Groot, Mark; Gardarsdottir, Helga; Brauer, Ruth; Grimaldi-Bensouda, Lamiae; Kurz, Xavier; Gasse, Christiane; Reynolds, Robert

    2014-01-01

    Background: Pharmacoepidemiological (PE) research should provide consistent, reliable and reproducible results to contribute to the benefit-risk assessment of medicines. IMI-PROTECT aims to identify sources of methodological variations in PE studies using a common protocol and analysis plan across

  8. Improving consistency in findings from pharmacoepidemiological studies: The IMI-protect (Pharmacoepidemiological research on outcomes of therapeutics by a European consortium) project

    NARCIS (Netherlands)

    De Groot, Mark C.H.; Schlienger, Raymond; Reynolds, Robert; Gardarsdottir, Helga; Juhaeri, Juhaeri; Hesse, Ulrik; Gasse, Christiane; Rottenkolber, Marietta; Schuerch, Markus; Kurz, Xavier; Klungel, Olaf H.

    2013-01-01

    Background: Pharmacoepidemiological (PE) research should provide consistent, reliable and reproducible results to contribute to the benefit-risk assessment of medicines. IMI-PROTECT aims to identify sources of methodological variations in PE studies using a common protocol and analysis plan across

  9. Complete nucleotide sequence of pGA45, a 140,698-bp incFIIY plasmid encoding blaIMI-3-mediated carbapenem resistance, from river sediment

    Directory of Open Access Journals (Sweden)

    Bingjun eDang

    2016-02-01

    Full Text Available Plasmid pGA45 was isolated from the sediment of Haihe River using E. coli CV601 (gfp-tagged as recipients and indigenous bacteria from sediment as donors. This plasmid confers reduced susceptibility to imipenem which belongs to carbapenem group. Plasmid pGA45 was fully sequenced on an Illumina HiSeq 2000 sequencing system. The complete sequence of plasmid pGA45 was 140,698 bp in length with an average G+C content of 52.03%. Sequence analysis shows that pGA45 belongs to incFIIY group and harbors a backbone region shares high homology and gene synteny to several other incF plasmids including pNDM1_EC14653, pYDC644, pNDM-Ec1GN574, pRJF866, pKOX_NDM1 and pP10164-NDM. In addition to the backbone region, plasmid pGA45 harbors two notable features including one blaIMI-3-containing region and one type VI secretion system region. The blaIMI-3-containing region is responsible for bacteria carbapenem resistance and the type VI secretion system region is probably involved in bacteria virulence, respectively. Plasmid pGA45 represents the first complete nucleotide sequence of the blaIMI-harboring plasmid from environment sample and the sequencing of this plasmid provided insight into the architecture used for the dissemination of blaIMI carbapenemase genes.

  10. Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblon-independent manner

    DEFF Research Database (Denmark)

    Dimopoulos, Konstantinos; Søgaard Helbo, Alexandra; Fibiger Munch-Petersen, Helga

    2018-01-01

    Thalidomide and its derivatives, lenalidomide and pomalidomide (also known as IMiDs), have significantly changed the treatment landscape of multiple myeloma, and the recent discovery of cereblon (CRBN) as their direct biological target has led to a deeper understanding of their complex mechanism ...

  11. 78 FR 63570 - Proposed Collection; Comment Request for Forms W-8BEN, W-8BEN-E, W-8ECI, W-8EXP, and W-8IMY

    Science.gov (United States)

    2013-10-24

    ... W-8BEN, W-8BEN-E, W-8ECI, W-8EXP, and W-8IMY AGENCY: Internal Revenue Service (IRS), Treasury..., the IRS is soliciting comments concerning Form W-8BEN, Certificate of Foreign Status of Beneficial Owner for United States Tax Withholding, Form W-8BEN-E, Certificate of Status of Beneficial Owner for...

  12. 75 FR 38179 - Proposed Collection; Comment Request for Forms W-8BEN, W-8ECI, W-8EXP, and W-8IMY

    Science.gov (United States)

    2010-07-01

    ... W-8BEN, W-8ECI, W- 8EXP, and W-8IMY AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice... soliciting comments concerning Form W-8BEN, Certificate of Foreign Status of Beneficial Owner for United States Tax Withholding, Form W-8ECI, Certificate of Foreign Person's Claim for Exemption From Withholding...

  13. Sierra/SD User's Notes.

    Energy Technology Data Exchange (ETDEWEB)

    Munday, Lynn Brendon; Day, David M.; Bunting, Gregory; Miller, Scott T; Crane, Nathan K

    2018-03-01

    Sierra/SD provides a massively parallel implementation of structural dynamics finite element analysis, required for high fidelity, validated models used in modal, vibration, static and shock analysis of weapons systems. This document provides a users guide to the input for Sierra/SD. Details of input specifications for the different solution types, output options, element types and parameters are included. The appendices contain detailed examples, and instructions for running the software on parallel platforms.

  14. Photometric Survey to Search for Field sdO Pulsators

    Science.gov (United States)

    Johnson, C.; Green, E.; Wallace, S.; O'Malley, C.; Amaya, H.; Biddle, L.; Fontaine, G.

    2014-04-01

    We present the results of a campaign to search for subdwarf O (sdO) star pulsators among bright field stars. The motivation for this project is the recent discovery by Randall et al. (2011) of four rapidly pulsating sdO stars in the globular cluster ω Cen, with Teff near 50,000 K, 5.4 -0.1 and similar temperatures and gravities. To date, we have found no detectable pulsations at amplitudes above 0.08% (4 times the mean noise level) in any of the 36 field sdO stars that we observed. The presence of pulsations in ω Cen sdO stars and their apparent absence in seemingly comparable field sdO stars is perplexing. While very suggestive, the significance of this result is difficult to assess more completely right now due to remaining uncertainties about the temperature width and purity of the ω Cen instability strip and the existence of any sdO pulsators with weaker amplitudes than the current detection limit in globular clusters.

  15. RECORD OF THE BINARY DATA ON SD CARD ARDUINO DUE

    Directory of Open Access Journals (Sweden)

    V. G. Mikhailov

    2016-01-01

    Full Text Available The short review of microcontrollers of family Arduino, their characteristics and application fields is given. Importance of record of parameters of researched object is marked to produce debugging of control systems on microcontrollers Arduino. Unique possibility of registration of parameters in family Arduino is record on SD a card in an alpha mode with usage of functions print (, write (. The problems connected to record of the binary data on SD a card on microcontroller Arduino Due are considered. The analysis of methods of record of the binary data on SD card Arduino Due, originating problems with neo-cleaning of memory from the previous program leading to possibility of duplication of the data on SD to a card, presence of the erratic point of view about restriction of volumes of data record and necessity of usage become outdated SD cards is carried out. Ways of elimination of the marked lacks are considered. The estimation of high-speed performance of various approaches of a data recording on SD a card is led. On the basis of the led researches the approach of multiplexing of the writeable information at the expense of conversion of the binary data is offered is byte-serial in a character array in code ASCI without magnification of their volume and record by units on 240 byte. It allows to use as much as possible standard function possibilities write ( Arduino and specificity of the organization of memory SD of cards and to increase high-speed performance more than in 1100 times in comparison with record in a character type on one byte.It is marked that usage of decisions of an exception of duplication of the data offered at forums does not provide completeness of their elimination. For Arduino Due for storage cleaning it is necessary usages of the special programmator or setting of the new program of loading.

  16. Purification, Characterization, and Optimum Conditions of Fermencin SD11, a Bacteriocin Produced by Human Orally Lactobacillus fermentum SD11.

    Science.gov (United States)

    Wannun, Phirawat; Piwat, Supatcharin; Teanpaisan, Rawee

    2016-06-01

    Fermencin SD11, a bacteriocin produced by human orally Lactobacillus fermentum SD11, was purified, characterized, and optimized in conditions for bacterial growth and bacteriocin production. Fermencin SD11 was purified using three steps of ammonium sulfate precipitation, gel filtration chromatography, and reverse-phase high-performance liquid chromatography. The molecular weight was found to be 33,000 Da using SDS-PAGE and confirmed as 33,593.4 Da by liquid chromatography-mass spectrometry. Fermencin SD11 exhibited activity against a wide range of oral pathogens including cariogenic and periodontogenic pathogens and Candida. The active activity was stable between 60 - 80 °C in a pH range of 3.0 to 7.0. It was sensitive to proteolytic enzymes (proteinase K and trypsin), but it was not affected by α-amylase, catalase, lysozyme, and saliva. The optimum conditions for growth and bacteriocin production of L. fermentum SD11 were cultured at acidic with pH of 5.0-6.0 at 37 or 40 °C under aerobic or anaerobic conditions for 12 h. It is promising that L. fermentum SD11 and its bacteriocin may be an alternative approach for promoting oral health or prevention of oral diseases, e.g., dental caries and periodontitis, which would require further clinical trials.

  17. The sdA problem - I. Physical properties

    Science.gov (United States)

    Pelisoli, Ingrid; Kepler, S. O.; Koester, D.

    2018-04-01

    The so-called sdA stars are defined by having H-rich spectra and surface gravities similar to hot subdwarf stars, but effective temperature below the zero-age horizontal branch. Their evolutionary history is an enigma: their surface gravity is too high for main-sequence stars, but too low for single evolution white dwarfs. They are most likely byproducts of binary evolution, including blue-stragglers, extremely-low mass white dwarf stars (ELMs) and their precursors (pre-ELMs). A small number of ELMs with similar properties to sdAs is known. Other possibilities include metal-poor A/F dwarfs, second generation stars, or even stars accreted from dwarf galaxies. In this work, we analyse colours, proper motions, and spacial velocities of a sample of sdAs from the Sloan Digital Sky Survey to assess their nature and evolutionary origin. We define a probability of belonging to the main sequence and a probability of being a (pre-)ELM based on these properties. We find that 7 per cent of the sdAs are more likely to be (pre-)ELMs than main-sequence stars. However, the spacial velocity distribution suggests that over 35 per cent of them cannot be explained as single metal-poor A/F stars.

  18. Intruder level and deformation in SD-pair shell model

    International Nuclear Information System (INIS)

    Luo Yan'an; Ning Pingzhi; Pan Feng

    2004-01-01

    The influence of intruder level on nuclear deformation is studied within the framework of the nucleon-pair shell model truncated to an SD-pair subspace. The results suggest that the intruder level has a tendency to reduce the deformation and plays an important role in determining the onset of rotational behavior. (authors)

  19. SD-CAS: Spin Dynamics by Computer Algebra System.

    Science.gov (United States)

    Filip, Xenia; Filip, Claudiu

    2010-11-01

    A computer algebra tool for describing the Liouville-space quantum evolution of nuclear 1/2-spins is introduced and implemented within a computational framework named Spin Dynamics by Computer Algebra System (SD-CAS). A distinctive feature compared with numerical and previous computer algebra approaches to solving spin dynamics problems results from the fact that no matrix representation for spin operators is used in SD-CAS, which determines a full symbolic character to the performed computations. Spin correlations are stored in SD-CAS as four-entry nested lists of which size increases linearly with the number of spins into the system and are easily mapped into analytical expressions in terms of spin operator products. For the so defined SD-CAS spin correlations a set of specialized functions and procedures is introduced that are essential for implementing basic spin algebra operations, such as the spin operator products, commutators, and scalar products. They provide results in an abstract algebraic form: specific procedures to quantitatively evaluate such symbolic expressions with respect to the involved spin interaction parameters and experimental conditions are also discussed. Although the main focus in the present work is on laying the foundation for spin dynamics symbolic computation in NMR based on a non-matrix formalism, practical aspects are also considered throughout the theoretical development process. In particular, specific SD-CAS routines have been implemented using the YACAS computer algebra package (http://yacas.sourceforge.net), and their functionality was demonstrated on a few illustrative examples. Copyright © 2010 Elsevier Inc. All rights reserved.

  20. Importance of prumycin produced by Bacillus amyloliquefaciens SD-32 in biocontrol against cucumber powdery mildew disease.

    Science.gov (United States)

    Tanaka, Keijitsu; Fukuda, Mutsumi; Amaki, Yusuke; Sakaguchi, Takatoshi; Inai, Koji; Ishihara, Atsushi; Nakajima, Hiromitsu

    2017-12-01

    Powdery mildew disease of cucurbits is caused mainly by Podosphaera fusca, which is one of the most important limiting factors in cucurbit production worldwide. Previously we reported that Bacillus amyloliquefaciens biocontrol strain SD-32 produces C 17 bacillomycin D and [Ile 2002]surfactin, and that these metabolites play important roles in SD-32's biocontrol over cucumber gray mold disease. Our further investigation demonstrated that the culture broth and its supernatant suppressed cucumber powdery mildew disease in greenhouse experiments. However, the active principle(s) remained unknown. The active compound was isolated from the culture supernatant after anti-powdery mildew disease activity-guided purification and identified as prumycin. Prumycin significantly suppressed the disease, whereas bacillomycin D and [Ile 2002]surfactin did not. Prumycin did not induce the expression of plant defense genes (PR1a and VSP1), suggesting that it does not act via plant defense response. Light microscopic observations of prumycin-treated cucumber cotyledon suggested that prumycin inhibits the conidial germination of P. fusca. This study demonstrates that prumycin is a major factor in SD-32's suppression of cucumber powdery mildew disease. Our findings shed light for the first time on prumycin's role in biocontrol by Bacillus against this disease. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  1. Impact of methodological choices on findings from pharmacoepidemiological studies: Final results of the IMI-protect (pharmacoepidemiological research on outcomes of therapeutics by a European consortium) project

    OpenAIRE

    Klungel, Olaf; De Groot, Mark; Gardarsdottir, Helga; Brauer, Ruth; Grimaldi-Bensouda, Lamiae; Kurz, Xavier; Gasse, Christiane; Reynolds, Robert

    2014-01-01

    Background: Pharmacoepidemiological (PE) research should provide consistent, reliable and reproducible results to contribute to the benefit-risk assessment of medicines. IMI-PROTECT aims to identify sources of methodological variations in PE studies using a common protocol and analysis plan across databases (including independent replication studies). In addition, differences by design, applied to a same drug-adverse event (AE) pair in different databases are examined. Results from PE studies...

  2. Resonances in collisions between S-D shell nuclei

    International Nuclear Information System (INIS)

    Betts, R.R.

    1984-01-01

    Experimental evidence relating to the existence of resonances in collisions between s-d shell nuclei will be reviewed. The determination of the spins and spectroscopic properties of some of these resonances will be discussed. The behaviour of both the resonance and background cross-sections will be compared with model expectations. Some future directions in this area of study will be indicated and the relationship of this work to other results briefly discussed. (author)

  3. Quasi-molecular states in sd-shell nuclei

    International Nuclear Information System (INIS)

    Kubono, S.; Ikeda, N.; Nomura, T.

    1988-08-01

    Quasi-molecular states near and below the threshold of the molecular configuration in sd-shell nuclei are discussed using recent experimental data with particle-gamma coincidence method and particle-particle coincidence method. Possible quasi-molecular states have been identified in 24 Mg as well as in 28 Si and 32 S. The important role of quasi-molecular states are discussed, specifically for the shape evolution of nuclei as a function of excitation energy and angular momentum. (author)

  4. Sex differences in the stress response in SD rats.

    Science.gov (United States)

    Lu, Jing; Wu, Xue-Yan; Zhu, Qiong-Bin; Li, Jia; Shi, Li-Gen; Wu, Juan-Li; Zhang, Qi-Jun; Huang, Man-Li; Bao, Ai-Min

    2015-05-01

    Sex differences play an important role in depression, the basis of which is an excessive stress response. We aimed at revealing the neurobiological sex differences in the same study in acute- and chronically-stressed rats. Female Sprague-Dawley (SD) rats were randomly divided into 6 groups: chronic unpredictable mild stress (CUMS), acute foot shock (FS) and controls, animals in all 3 groups were sacrificed in proestrus or diestrus. Male SD rats were randomly divided into 3 groups: CUMS, FS and controls. Comparisons were made of behavioral changes in CUMS and control rats, plasma levels of corticosterone (CORT), testosterone (T) and estradiol (E2), and of the hypothalamic mRNA-expression of stress-related molecules, i.e. estrogen receptor α and β, androgen receptor, aromatase, mineralocorticoid receptor, glucocorticoid receptor, corticotropin-releasing hormone, arginine vasopressin and oxytocin. CUMS resulted in disordered estrus cycles, more behavioral and hypothalamic stress-related molecules changes and a stronger CORT response in female rats compared with male rats. Female rats also showed decreased E2 and T levels after FS and CUMS, while male FS rats showed increased E2 and male CUMS rats showed decreased T levels. Stress affects the behavioral, endocrine and the molecular response of the stress systems in the hypothalamus of SD rats in a clear sexual dimorphic way, which has parallels in human data on stress and depression. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Nar Suyunun Kimyasal Bileşimi ve Tanı Değerleri (İngilizce

    Directory of Open Access Journals (Sweden)

    Aziz Ekşi

    2015-02-01

    Full Text Available Tanı değerlerinin belirlenmesine katkıda bulunmak için, 23 konsantreden nar suyu örneğinin kimyasal bileşimi araştırıldı. Örnekler, 2006 yılında 6 farklı üretici firmadan sağlandı. Bulgulara göre; 14° briksteki nar suyunda titrasyon asitliği 8.3-17.4 g/L (susuz sitrik asit olarak, sitrik asit 6.6-13.6 g/L, L-malik asit 0.5-0.9 g/L, D-izositrik asit 3.9-86 mg/L, glukoz 45.8- 65.6 g/L, früktoz 48.4- 69.9 g/L, potasyum 2093-2517 mg/L, fosfor 93-151 mg/L, kalsiyum 11-149 mg/L, magnezyum 21-104 mg/L ve sodyum 20-128 mg/L arasında değişmektedir.

  6. Elucidating the 16S rRNA 3' boundaries and defining optimal SD/aSD pairing in Escherichia coli and Bacillus subtilis using RNA-Seq data.

    Science.gov (United States)

    Wei, Yulong; Silke, Jordan R; Xia, Xuhua

    2017-12-15

    Bacterial translation initiation is influenced by base pairing between the Shine-Dalgarno (SD) sequence in the 5' UTR of mRNA and the anti-SD (aSD) sequence at the free 3' end of the 16S rRNA (3' TAIL) due to: 1) the SD/aSD sequence binding location and 2) SD/aSD binding affinity. In order to understand what makes an SD/aSD interaction optimal, we must define: 1) terminus of the 3' TAIL and 2) extent of the core aSD sequence within the 3' TAIL. Our approach to characterize these components in Escherichia coli and Bacillus subtilis involves 1) mapping the 3' boundary of the mature 16S rRNA using high-throughput RNA sequencing (RNA-Seq), and 2) identifying the segment within the 3' TAIL that is strongly preferred in SD/aSD pairing. Using RNA-Seq data, we resolve previous discrepancies in the reported 3' TAIL in B. subtilis and recovered the established 3' TAIL in E. coli. Furthermore, we extend previous studies to suggest that both highly and lowly expressed genes favor SD sequences with intermediate binding affinity, but this trend is exclusive to SD sequences that complement the core aSD sequences defined herein.

  7. ANALISIS REKRUITMEN TENAGA PENDIDIK PADA SD KALAM KUDUS PEKANBARU

    Directory of Open Access Journals (Sweden)

    Murnawati Murnawati

    2015-04-01

    Full Text Available Abstrak: Penelitian ini dilakukan untuk mengetahui sistem rekrutmen tenaga pendidik pada SD kalam kudus kota Pekanbaru. Populasi dalam penelitian ini adalah tenaga pendidik di SD Kalam Kudus Kota Pekanbaru, kebutuhan guru sebanyak 65 sedangkan guru tetap sebanyak 40 guru dan sisanya guru honor sebanyak 25 guru. Dalam penelitian ini penulis mengambil sampel seluruh populasi. Pengambilan sampel dilakukan secara sensus. Data yang digunakan adalah data primer yang diperoleh dari wawancara langsung dan penyebaran kuesioner. Analisis data dalam penelitian ini adalah menggunakan metode deskriptif. Berdasarkan hasil penelitian dapat disimpulkan bahwa persyaratan administrasi dalam rekruitmen guru diperoleh rata – rata skor sebesar 3,49. Artinya persyaratan administrasi dalam rekruitmen guru pada SD Kalam Kudus Pekanbaru dinilai baik. Abstract: This research aimed to determine the system of teachers’s recruitment in Kalam Kudus elementary school of Pekanbaru. The population in this study were educators in in Kalam Kudus elementary school of Pekanbaru, the teacher needs as much as 65 while the teacher remains as much as 40 teachers and teacher salaries remaining 25 teachers. In this study the authors took samples of the entire population. Sampling was done by census. The data used is primary data obtained from interviews and questionnaires. Data analyzed by descriptive method. Based on the results of this study concluded that the administrative requirements for the recruitment of teachers obtained average - average score of 3.49. This means that the administrative requirements for the recruitment of teachers in elementary Holy Kalam Pekanbaru considered good. Kata Kunci : Rekruitmen, Tenaga Pendidik

  8. A weak magnetic field inhibits hippocampal neurogenesis in SD rats

    Science.gov (United States)

    Zhang, B.; Tian, L.; Cai, Y.; Pan, Y.

    2017-12-01

    Geomagnetic field is an important barrier that protects life forms on Earth from solar wind and radiation. Paleomagnetic data have well demonstrated that the strength of ancient geomagnetic field was dramatically weakened during a polarity transition. Accumulating evidence has shown that weak magnetic field exposures has serious adverse effects on the metabolism and behaviors in organisms. Hippocampal neurogenesis occurs throughout life in mammals' brains which plays a key role in brain function, and can be influenced by animals' age as well as environmental factors, but few studies have examined the response of hippocampal neurogenesis to it. In the present study, we have investigated the weak magnetic field effects on hippocampal neurogenesis of adult Sprague Dawley (SD) rats. Two types of magnetic fields were used, a weak magnetic field (≤1.3 μT) and the geomagnetic fields (51 μT).The latter is treated as a control condition. SD rats were exposure to the weak magnetic field up to 6 weeks. We measured the changes of newborn nerve cells' proliferation and survival, immature neurons, neurons and apoptosis in the dentate gyrus (DG) of hippocampus in SD rats. Results showed that, the weak magnetic field (≤1.3 μT) inhibited their neural stem cells proliferation and significantly reduced the survival of newborn nerve cells, immature neurons and neurons after 2 or 4 weeks continuous treatment (i.e. exposure to weak magnetic field). Moreover, apoptosis tests indicated the weak magnetic field can promote apoptosis of nerve cells in the hippocampus after 4 weeks treatment. Together, our new data indicate that weak magnetic field decrease adult hippocampal neurogenesis through inhibiting neural stem cells proliferation and promoting apoptosis, which provides useful experimental constraints on better understanding the mechanism of linkage between life and geomagnetic field.

  9. Magnetic resonance spectroscopy of traumatic brain in SD rats model

    International Nuclear Information System (INIS)

    Li Ke; Li Yangbin; Li Zhiming; Huang Yong; Li Bin; Lu Guangming

    2009-01-01

    Objective: To assess the value and prospect of magnetic resonance spectroscopy (MRS) in early diagnosis of traumatic brain with traumatic brain model in SD rats. Methods: Traumatic brain modal was established in 40 male SD rats utilizing a weigh-drop device, and MRS was performed before trauma and 4,8,24 and 48 hours after trauma. The ratio of N-acetylaspartate/creatine (NAA/Ct) and choline/creatine (Cho/Cr) were calculated and compared with pathological findings respectively. Results: Axonal changes were confirmed in microscopic study 4 hours after injury. The ratio of NAA/Ct decreased distinctly at 4 hours after trauma, followed by a steadily recover at 8 hours, and no significant change from 24h to 48h. There was no significant change in the ratio of Cho/Cr before and after trauma. Conclusion: MRS can be used to monitor the metabolic changes of brain non-invasively. MRS could play a positive role in early diagnosis, prognosis and follow-up of traumatic brain. (authors)

  10. Clustering aspects of sd shell nuclei studied by AMD

    Energy Technology Data Exchange (ETDEWEB)

    Kimura, Masaaki [Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto 606-8502 (Japan); Taniguchi, Yasutaka [Department of Physics, Kyoto University, Kitashirakawa, Kyoto 606-8502 (Japan); En' yo, Yoshiko [Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto 606-8502 (Japan); Horiuchi, Hisashi [Department of Physics, Kyoto University, Kitashirakawa, Kyoto 606-8502 (Japan)

    2006-10-10

    The new clustering aspects of sd-shell nuclei found by the recent application of the antisymmetrized molecular dynamics are reported. In this paper we present two topics, 'superdeformed band of {sup 32}S and {sup 16}O + {sup 16}O clustering' and 'molecular-orbital and di-nuclei states in {sup 22}Ne'. In the first topic, it will be shown that the superdeformed band of 32S has a considerable amount of {sup 16}O + {sup 16}O cluster component, and can be regarded as to belong to a family of the {sup 16}O + {sup 16}O molecular bands. In the second topic, the presence of the molecularorbital band which has an {alpha} + {sup 16}O cluster core surrounded by two covalently neutrons is suggested together with an {alpha} + {sup 18}O di-nuclei band.

  11. Clustering aspects of sd shell nuclei studied by AMD

    International Nuclear Information System (INIS)

    Kimura, Masaaki; Taniguchi, Yasutaka; En'yo, Yoshiko; Horiuchi, Hisashi

    2006-01-01

    The new clustering aspects of sd-shell nuclei found by the recent application of the antisymmetrized molecular dynamics are reported. In this paper we present two topics, 'superdeformed band of 32 S and 16 O + 16 O clustering' and 'molecular-orbital and di-nuclei states in 22 Ne'. In the first topic, it will be shown that the superdeformed band of 32S has a considerable amount of 16 O + 16 O cluster component, and can be regarded as to belong to a family of the 16 O + 16 O molecular bands. In the second topic, the presence of the molecularorbital band which has an α + 16 O cluster core surrounded by two covalently neutrons is suggested together with an α + 18 O di-nuclei band

  12. Clustering correlations and triaxiality in the sd-shell region

    International Nuclear Information System (INIS)

    Taniguchi, Yasutaka; Kimura, Masaaki; Kanada-En'yo, Yoshiko; Horiuchi, Hisashi

    2011-01-01

    Effects of cluster correlations on triaxiality have been studied using the antisymmetrized molecular dynamics. Low-lying states in 28 Si and 40 Ca are obtained by the generator coordinate method (GCM), and the GCM basis are calculated by energy variations with constraints on quadrupole deformation parameter β and inter-cluster distance. The GCM obtain prolate superdeformed (SD) states in 28 Si and triaxial normal-deformed (ND) states in 40 Ca, which contain prolate α- 24 Mg and triaxial α- 36 Ar cluster structure components, respectively. Different shapes of prolate 24 Mg and oblate 36 Ar clusters cause difference of triaxiality of total systems. Cluster correlations which have oblate cluster enhance triaxiality in excited states. (author)

  13. SATUS GIZI TIDAK SIGNIFIKAN MENENTUKAN PRESTASI SISWA SD

    Directory of Open Access Journals (Sweden)

    Dian Vista

    2014-04-01

    Full Text Available Background : The low Human Development Index (HDI ranking in Indonesia compared withneighboring countries affected by the low nutritional status and health problems of Indonesia’a populationfactor.One of the factor’s facing the health problem’s of Indonesian society is the problem of nutrition,undertrition and obessitas. They both have a negative impact on the quality of health. Government’sefforts to improve nutrition in school children by providing the Food Supplement Program School Children(PMT-AS. Good nutritional status is necessary for physical growth, brain development, employability andoptimal health. Abnormalities that occur in the brain due to malnutritional have one impact is the declinein brain function that affects the ability to learn, resulting in lower children’s learning outcome.Objective :To determine the relationship of nutritional status and student achievement in elementaryschool Bangunjiwo Kasihan Bantul Yogyakarta.Methods :This study used non-experimental research methods with cross sectional approach. Thepopulation in this study were student in grade 6 in SD Negeri Bangunjiwo Kasihan Bantul. The samplesused were 43 students. Engineering samples of the total samplingobtained a total sample of 43 studentsand analize using Spearman.Results :Nutritional status in elementary school Bangunjiwo Kasihan Bantul there are 36 students(83,7% in the normal category of 43 respondents. A grade students achievement 6 in SD NegeriBangunjiwo Kasihan Bantul most in categories as many 28 students (65,1% of the 43 respondent.Conclusion :There was no significant association between nutritional status of student performance,with a value of (p>0,05.

  14. Neural nets for the plausibility check of measured values in the integrated measurement and information system for the surveillance of environmental radioactivity (IMIS)

    International Nuclear Information System (INIS)

    Haase, G.

    2003-01-01

    Neural nets to the plausibility check of measured values in the ''integrated measurement and information system for the surveillance of environmental radioactivity, IMIS'' is a research project supported by the Federal Minister for the Environment, Nature Conservation and Nuclear Safety. A goal of this project was the automatic recognition of implausible measured values in the data base ORACLE, which measured values from surveillance of environmental radioactivity of most diverse environmental media contained. The conversion of this project [ 1 ] was realized by institut of logic, complexity and deduction systems of the university Karlsruhe under the direction of Professor Dr. Menzel, Dr. Martin Riedmueller and Martin Lauer. (orig.)

  15. Reducing mutans streptococci and caries development by Lactobacillus paracasei SD1 in preschool children: a randomized placebo-controlled trial.

    Science.gov (United States)

    Pahumunto, Nuntiya; Piwat, Supatcharin; Chankanka, Oitip; Akkarachaneeyakorn, Nuchnaree; Rangsitsathian, Karnrawee; Teanpaisan, Rawee

    2018-03-22

    To examine a reducing effect of Lactobacillus paracasei SD1 on MS and caries in preschool children. A total of 124 children, aged 1.5-5 years old, participated and were randomly assigned to the probiotic or control group. The probiotic group received L. paracasei SD1-milk and the control group received standard-milk once daily for 3 months. MS/lactobacilli were enumerated and the caries score was examined. Association between probiotic consumption and bacterial level, or caries progression was assessed by a multivariate logistic regression. This study was registered at the Thai-Clinical-Trials-Registry (TCTR20140903001). Probiotic was found to be a factor associated with the MS level. Children in the probiotic group had a significantly lower risk of an increase in the MS level than in the control group after receiving the probiotic milk at 3- and 4-months with p < .001 and p = .040, respectively. Probiotic significantly reduced the risk for caries compared to the control group (p = .016). There were no adverse effects or non-compliance reported in either group. Consumption of milk powder containing L. paracasei SD1 resulted in a reduction of both salivary MS and delayed new caries development, and the strain is safe for use in young children. Results suggest that L. paracasei SD1 may be an alternative way for caries prevention in young children.

  16. PEMBELAJARAN TEMATIK YANG IDEAL DI SD/MI

    Directory of Open Access Journals (Sweden)

    Sun Haji

    2015-03-01

    Full Text Available Anak usia sekolah / 6-12 tahun disebut masa sekolah, karena anak sudah menamatkan taman kanak-kanak sebagai lembaga persiapan bersekolah yang sebenarnya. Disebut masa matang untuk belajar, Karena anak sudah berusaha untuk mencapai sesuatu, tetapi, perkembangan aktivitas bermain yang hanya bertujuan untuk mendapatkan kesenangan pada waktu melakukan aktivitas itu sendiri. Disebut masa matang untuk sekolah, karena anak sudah menginginkan kecakapan-kecakapan baru, yang dapat diberikan oleh sekolah (Nasution Noehi, 1993: 44. Menurut Banett, dkk., karakteristik anak usia SD, antara lain sebagai berikut. (1 Mereka secara alamiah memiliki rasa ingin tahu yang kuat dan tertarik akan dunia sekitar yang mengelilingi diri mereka sendiri. (2 Senang bermain dan lebih suka bergembira. (3 Suka mengatur dirinya untuk menangani berbagai hal, mengeksplorasi suatu situasi dan mencoba usaha-usaha baru. (4 biasanya tergetar perasaannya dan terdorong untuk berprestasi sebagaimana mereka tidak suka mengalami ketidakpuasan dan menolak kegagalan-kegagalan. (5 Belajar secara efektif ketika merasa puas dengan situasi yang terjadi. (6 Belajar dengan cara bekerja, mengobservasi, berinisiatif dan mengajar anak-anak lainnya ( Mulyani Sumantri & Nana Syaodih, 2000: 12.

  17. Chemical fingerprints of He-sdO stars

    Directory of Open Access Journals (Sweden)

    Schindewolf Markus

    2018-02-01

    Full Text Available The chemical composition of helium-rich hot subluminous O stars plays an important role to understand and model their formation history. We present a spectroscopic analysis of four He-sdO stars,CD-31° 4800, [CW83] 0904- 02, LSS 1274 and LS IV +10° 9. The analysis is based on archival optical and UV high-resolution spectra. We used Tlusty200/Synspec48 to compute line blanketed non-LTE model atmospheres and their corresponding synthetic spectra and derive the atmospheric parameters as well as the abundances of the most prominent elements. All stars have helium-dominated atmospheres with hardly any hydrogen and temperatures between 42000 K and 47000 K while their surface gravity spans between log g = 5.4 and 5.7. CD-31° 4800 shows an enrichment of nitrogen and the characteristic pattern of hydrogen burning via the CNO-cycle, while the rest of the elements have about the solar abundance. This points to the slow merger of two helium white dwarfs as the most likely origin for this system. The other three stars are enriched in carbon, nitrogen and neon while their intermediate mass element’s abundance scatters around the solar value. They were possibly formed in the deep mixing late hot flasher scenario.

  18. Chemical fingerprints of He-sdO stars

    Science.gov (United States)

    Schindewolf, Markus; Németh, Peter; Heber, Ulrich; Battich, Tiara; Miller Bertolami, Marcelo M.; Latour, Marilyn

    2018-02-01

    The chemical composition of helium-rich hot subluminous O stars plays an important role to understand and model their formation history. We present a spectroscopic analysis of four He-sdO stars,CD-31° 4800, [CW83] 0904- 02, LSS 1274 and LS IV +10° 9. The analysis is based on archival optical and UV high-resolution spectra. We used Tlusty200/Synspec48 to compute line blanketed non-LTE model atmospheres and their corresponding synthetic spectra and derive the atmospheric parameters as well as the abundances of the most prominent elements. All stars have helium-dominated atmospheres with hardly any hydrogen and temperatures between 42000 K and 47000 K while their surface gravity spans between log g = 5.4 and 5.7. CD-31° 4800 shows an enrichment of nitrogen and the characteristic pattern of hydrogen burning via the CNO-cycle, while the rest of the elements have about the solar abundance. This points to the slow merger of two helium white dwarfs as the most likely origin for this system. The other three stars are enriched in carbon, nitrogen and neon while their intermediate mass element's abundance scatters around the solar value. They were possibly formed in the deep mixing late hot flasher scenario.

  19. KEMAMPUAN BERPIKIR KREATIF SISWA SD DALAM PEMBELAJARAN IPA

    Directory of Open Access Journals (Sweden)

    Jamaluddin Jamaluddin

    2016-02-01

    Full Text Available Abstract: Elementary School Studens' Creative Thinking Skills in Science Learning. This study aims (1 to investigate the differences of creative thinking skills among elementary school students who applied various learning methods (questioning, Think-Pair-Share, and Numbered-Head together and those who applied conventional learning methods; (2 to find out the differences in creative thinking skills between students of high and low academic ability; (3 to investigate the differences of creative thinking skills as influ­enced by learning methods and academic ability. Using a quasi -experimental design, this study found out that there are differences in creative thinking skills among students applying different learning methods and among students of different academic abilities and that these differences in creative thinking are skills as influenced by learning methods and academic abilities. Abstrak: Kemampuan Berpikir Kreatif Siswa SD dalam Pembelajaran IPA. Artikel ini didasarkan pada laporan penelitian yang bertujuan untuk mengetahui (1 perbedaan keterampilan berpikir kreatif, antara siswa yang belajar dengan strategi pembelajaran PBMP, PBMPTPS, PBMPNHT, dan strategi pembelajaran konvensional; (2 perbedaan keterampilan berpikir kreatif siswa berkemampuan akademik tinggi dan rendah; (3 perbedaan keterampilan berpikir kreatif akibat dari interaksi antara strategi pembelajaran dengan kemampuan akademik siswa. Hasil penelitian menunjukkan (1 ada perbedaan keterampilan berpikir kreatif antara siswa yang belajar dengan strategi PBMP, PBMPTPS, PBMPNHT, dan strategi Konven­sional; (2 ada perbedaan keterampilan berpikir kreatif, antara siswa berkemampuan akademik tinggi dengan siswa berkemampuan akademik rendah; (3 interaksi strategi pembelajaran PBMP, PBMP.TPS, PBMP.NHT, dan konvensional dengan kemampuan akademik siswa tidak berpengaruh signifikan terhadap keterampilan berpikir kreatif.

  20. Product of the SNPP VIIRS SD Screen Transmittance and the SD BRDF (RSB) From Both Yaw Maneuver and Regular On-Orbit Data

    Science.gov (United States)

    Lei, Ning; Xiong, Xiaoxiong

    2016-01-01

    To assure data quality, the Earth-observing Visible Infrared Imaging Radiometer Suite (VIIRS) regularly performs on-orbit radiometric calibrations of its 22 spectral bands. The primary calibration radiance source for the reflective solar bands (RSBs) is a sunlit solar diffuser (SD). During the calibration process, sunlight goes through a perforated plate (the SD screen) and then strikes the SD. The SD scattered sunlight is used for the calibration, with the spectral radiance proportional to the product of the SD screen transmittance and the SD bidirectional reflectance distribution function (BRDF). The BRDF is decomposed to the product of its value at launch and a numerical factor quantifying its change since launch. Therefore, the RSB calibration requires accurate knowledge of the product of the SD screen transmittance and the BRDF (RSB; launch time). Previously, we calculated the product with yaw maneuver data and found that the product had improved accuracy over the prelaunch one. With both yaw maneuver and regular on orbit data, we were able to improve the accuracy of the SDSM screen transmittance and the product for the solar diffuser stability monitor SD view. In this study, we use both yaw maneuver and a small portion of regular on-orbit data to determine the product for the RSB SD view.

  1. Role of viability of probiotic strains in their persistence in the gut and in mucosal immune stimulation.

    Science.gov (United States)

    Galdeano, C Maldonado; Perdigón, G

    2004-01-01

    To determine how probiotic bacteria contact with intestinal epithelial and immune cells and the conditions to induce a good mucosal immune stimulation. Lactobacillus casei was studied by transmission electron microscopy (TEM) to determine its interaction with the gut. We compared the influence of viable and nonviable lactic acid bacteria on the intestinal mucosal immune system (IMIS) and their persistence in the gut of mice. TEM showed whole Lact. casei adhered to the villi; the bacterial antigen was found in the cytoplasm of the enterocytes. Viable bacteria stimulated the IMIS to a greater extent than nonviable bacteria with the exception of Lact. delbrueckii subsp. bulgaricus. For all the strains assayed at 72 h no antigenic particles were found in the intestine. Antigenic particles but not the whole bacteria can enter to epithelial cells and contact with the immune cells. Bacterial viability is a condition for a better stimulation of the IMIS. We demonstrated that only antigenic particle interact with the immune cells and their fast clearance from the gut agrees with those described for the particulate antigens. The regular consumption of probiotics should not adversely affect the host.

  2. Penerapan Metoda Serial Peripheral Interface (SPI pada Rancang Bangun Data Logger berbasis SD card

    Directory of Open Access Journals (Sweden)

    RATNA SUSANA

    2018-03-01

    Full Text Available ABSTRAK Serial Peripheral Interface (SPI adalah protokol komunikasi yang dapat digunakan sebagai interface komunikasi antara mikrokontroler dengan SD Card. Dengan menerapkan metoda SPI pada data logger berbasis SD Card, maka dapat diketahui karakteristik protokol komunikasi SPI antara mikrokontroler dengan SD Card. SD Card diformat dengan tipe FAT 16, dan data di dalam SD Card berupa sekumpulan paket data sensor yang diambil secara periodik dan disimpan dalam bentuk file dengan format.csv. Berdasarkan format paket data sensor yang dibuat, dapat dihitungwaktu perekaman data yang diperlukan agar kapasitas SD Card terisi penuh oleh data sensor. Hasil penelitian menunjukkan,bahwa metoda SPI yang diterapkan pada penelitian ini memiliki sifat akan melakukan pemeriksaan berulang pada pin MISO terhadap command yang dikirimkan oleh mikrokontroler melalui pin MOSI. Proses read/write data pada SD Card data logger memiliki keberhasilan 100%, karena SD Card telah terinisialisasi dalam mode SPI melalui perintah reset dan init SD Card. Komunikasi ini dapat dilakukan dengan menggunakan crystal 4 Mhz – 20 Mhz. Untuk pengujian konfigurasi SPI, hanya Independent Slave Configuration yang dapat digunakan pada komunikasi SPI dengan 2 SD card sebagai slave. Kata kunci: Serial Peripheral Interface (SPI, Data Logger, SD card, FAT16 ABSTRACT Serial Peripheral Interface (SPI is a communication protocol that can be applied as a communication interface between microcontroller to SD Card. By implementing the SPI method to a data logger based on SD Card, it can be known the characteristics of the SPI communications protocol between microcontroller to SD Card. SD Card formatted in FAT 16 type, and data on the SD Card is the form of sensor data packets collection which be captured periodically and saved in .csv format file. Based on the sensor data packet format is created, it can be calculated recording time data required so that the SD Card capacity completely filled by the

  3. Research and development project of regional consortiums in fiscal 1998. Research and development of regional consortium energy (development of measuring technology to aid energy conservation in electronic device manufacturing processes (design and trial production of IMI) (Report on the result in the first year)); 1998 nendo chiiki consortium energy kenkyu kaihatsu. Denshi kikirui seizo process no sho energy shien keisoku seigyo gijutsu no kaihatsu (IMI no sekkei to shisaku) (dai 1 nendo)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This paper summarizes the development of intelligent micro instruments (IMI) inaugurated in fiscal 1998 as the wide-area consortium project for the Tama area. Research and development will be carried out on the following items: IMI substrate elements utilizing micro machining technology, applicable to micro sensors and micro probes, semiconductor process sensors, electronic device measuring probes, signal processing and communication circuits for wireless sensing. This paper describes the achievements during fiscal 1998. Technologies were transferred from the Mechanical Engineering Laboratory of the Agency of Industrial Science and Technology on silicon micro machining and PZT piezoelectric thin film formation. An IMI research laboratory was installed at the Tokyo Metropolitan University. In developing the IMI substrate elements, different beams applicable to sensors and probes were fabricated on a trial basis, and their mechanical properties were measured. For the semiconductor process sensors, discussions were given on micronization on a chlorine ion analyzer. In developing the electronic device measuring probes, the target was placed on measurement of in-situ characteristics of IC chips on a wafer. A prototype transmitting and receiving circuit board was fabricated for developing the wireless sensing. (NEDO)

  4. Effect of Long-Term Consumption of Lactobacillus paracasei SD1 on Reducing Mutans streptococci and Caries Risk: A Randomized Placebo-Controlled Trial

    Directory of Open Access Journals (Sweden)

    Rawee Teanpaisan

    2015-04-01

    Full Text Available Background: A previous study revealed Lactobacillus paracasei SD1, a probiotic strain, could reduce mutans streptococci (MS. The aim of this study was to evaluate the long-term effects of L. paracasei SD1 on the colonization of MS, and whether caries lesions developed. Methods: After informed consent, 122 children were recruited and randomly assigned to the probiotic or control groups. The probiotic group received milk-powder containing L. paracasei SD1 and the control group received standard milk-powder once daily for six months. Salivary MS and lactobacilli were enumerated using differential culture at baseline and at three-month intervals for 12 months. The persistence of L. paracasei SD1 was investigated using AP-PCR for DNA-fingerprinting. Oral health was examined at baseline and at the end of the study according to WHO criteria. Results: The long-term consumption could prolong colonization of L. paracasei SD1. Significantly reduced MS counts and increased lactobacilli levels were found among children in the probiotic group. There were less caries lesions in the probiotic group at the end of the study. A significant reduction of the development of new caries lesions (4.5 times was observed in the high caries risk group but not in the low caries risk group. Conclusions: Results demonstrate that the long-term daily ingestion of the human-derived probiotic L. paracasei SD1 significantly reduces the number of MS and caries risk in the high caries group.

  5. Experimental design and reporting standards for improving the internal validity of pre-clinical studies in the field of pain: Consensus of the IMI-Europain consortium

    DEFF Research Database (Denmark)

    Knopp, K.L.; Stenfors, C.; Baastrup, Cathrine Søndergaard

    2015-01-01

    that recommendations on how to improve these factors are warranted. Methods Members of Europain, a pain research consortium funded by the European Innovative Medicines Initiative (IMI), developed internal recommendations on how to improve the reliability of pre-clinical studies between laboratories. This guidance...... and conduct, and data analysis and interpretation. Key principles such as sample size calculation, a priori definition of a primary efficacy measure, randomization, allocation concealments, and blinding are discussed. In addition, considerations of how stress and normal rodent physiology impact outcome...... development in order to estimate possible publication bias is discussed. Conclusions More systematic research is needed to analyze how inadequate internal validity and/or experimental bias may impact reproducibility across pre-clinical pain studies. Addressing the potential threats to internal validity...

  6. Linkage relationship between semi-dwarfing gene sd-1 and gene for grain shattering in rice

    International Nuclear Information System (INIS)

    Oba, S.; Kikuchi, F.

    1990-01-01

    Full text: Most semidwarf rice cultivars carry the same gene sd-1. We observed an association between semi-dwarfness and grain shattering in isogenic lines carrying sd-1 from different sources in the background of the Japanese tall cultivar 'Norin 28'. The shattering was found to be caused by a single recessive gene, sh-2, linked to the sd-1 locus. The shattering gene seems to have been transmitted to many semi-dwarf cultivars together with sd-1, not only from 'Dee-geo-woo-gen' but also from the indica-cultivar 'Ai-jio-nan-te' and the japonica cultivar 'Shiranui'. (author)

  7. STUDI KOMPARASI BUDAYA SEKOLAH SDSN DAN SD EKS RSBI DI DAERAH ISTIMEWA YOGYAKARTA

    Directory of Open Access Journals (Sweden)

    Taufik Muhtarom

    2013-07-01

    Full Text Available Penelitian ini bertujuan untuk: (1 mengetahui perbedaan budaya sekolah di SDSN dan SD Eks RSBI DIY, (2 memaparkan perbedaan masing-masing aspek budaya sekolah antara SDSN dengan SD Eks RSBI. Jenis penelitian ini adalah komparasi. Populasi penelitian ini adalah semua kepala sekolah, guru, dan staf SDSN dan SD RSBI di Daerah Istimewa Yogyakarta yang berjumlah 797 orang untuk SDSN dan 155 orang untuk SD Eks RSBI. Sampel dari SDSN berjumlah 256 orang dan sampel dari SD Eks RSBI sebanyak 116 orang ditentukan menggunakan teknik proportional sampling. Pengumpulan data dilakukan menggunakan kuesioner. Teknik analisis data yang digunakan adalah analisis univariat, bivariat, dan uji-t. Hasil penelitian ini menunjukkan bahwa: (1 tidak terdapat perbedaan yang signifikan antara budaya sekolah SDSN dengan SD Eks RSBI di Daerah Istimewa Yogyakarta; (2 ditemukan perbedaan skor dari masing-masing aspek budaya sekolah di SDSN dan SD Eks RSBI DIY. Aspek budaya sekolah yang lebih baik di SDSN adalah kolaborasi profesional, hubungan kolegial, self determination, visi-misi, konsensus, dan disiplin. Sedangkan aspek budaya sekolah yang lebih unggul pada SD Eks RSBI adalah aspek komitmen, hormat, empati, bebas bullying dan artefak fisik. Kata kunci: budaya sekolah, SDSN, SD Eks RSBI

  8. Study of Hot Salt Stress Corrosion Crack Initiation of Alloy IMI 834 by using DC Potential Drop Method

    Energy Technology Data Exchange (ETDEWEB)

    Pustode, Mangesh D. [Bharat Forge Ltd., Pune (India); Dewangan, Bhupendra [Tata Steel, Jamshedpur (India); Raja, V. S. [Indian Institute of Technology Bombay, Mumbai (India); Paulose, Neeta; Babu, Narendra [Gas Turbine Research Establishment (GTRE), Bangalore (India)

    2016-10-15

    DC potential drop technique was employed during the slow strain rate tests to study the hot salt stress corrosion crack (HSSCC) initiation at 300 and 400 ℃. Threshold stresses for HSSCC initiation were found to about 88 % of the yield strength at both temperatures, but the time from crack initiation to final failure (Δtscc) decreased significantly with temperature, which reflects larger tendency for brittle fracture and secondary cracking. The brittle fracture features consisted of transgranular cracking through the primary α grain and discontinuous faceted cracking through the transformed β grains.

  9. Evaluation of SD BIOLINE H. pylori Ag rapid test against double ELISA with SD H. pylori Ag ELISA and EZ-STEP H. pylori Ag ELISA tests.

    Science.gov (United States)

    Negash, Markos; Kassu, Afework; Amare, Bemnet; Yismaw, Gizachew; Moges, Beyene

    2018-01-01

    Helicobacter pylori antibody titters fall very slowly even after successful treatment. Therefore, tests detecting H. pylori antibody lack specificity and sensitivity. On the other hand, H. pylori stool antigen tests are reported as an alternative assay because of their reliability and simplicity. However, the comparative performance of H. pylori stool antigen tests for detecting the presence of the bacterium in clinical specimens in the study area is not assessed. Therefore, in this study we evaluated the performance of SD BIOLINE H. pylori Ag rapid test with reference to the commercially available EZ- STEP ELISA and SD BIOLINE H. pylori Ag ELISA tests. Stool samples were collected to analyse the diagnostic performance of SD BIOLINE H. pylori Ag rapid test kit using SD H. pylori Ag ELISA kit and EZ- STEP ELISA tests as a gold standard. Serum samples were also collected from each patient to test for the presence of H. pylori antibodies using dBest H. pylori Test Disk. Sensitivity, specificity, predictive values and kappa value are assessed. P values H. pylori Ag rapid test were: 95.6% (95% CI, 88.8-98.8), 92.5% (95%CI, 89-94.1%), 86.7% (95% CI, 80.5-89.6), and 97.6% (95% CI, 993.9-99.3) respectively. The performance of SD BIOLINE H. pylori Ag rapid test was better than the currently available antibody test in study area. Therefore, the SD BIOLINE Ag rapid stool test could replace and be used to diagnose active H. pylori infection before the commencement of therapy among dyspeptic patients.

  10. Penelitian Serologis Polio pada Anak SD Pasca Bias-polio di Kabupaten Bogor

    OpenAIRE

    Gendrowahyuhono, Gendrowahyuhono; Yulitasari, Yulitasari; Purnamawati, Sinta; Klino, Klino

    2003-01-01

    Program BIAS-Polio sudah dilaksanakan pada bulan Nopember 1999 di seluruh SD di Indonesia dari kelas III sampai dengan kelas VI. Tujuan BIAS-Polio adalah untuk meningkatkan status imunitas anak terhadap infeksi virus polio sebingga dapat menghambat sirkulasi virus polio liar di masyarakat. Bias polio diberikan pada anak SD sebanyak 1 kali dosis.

  11. Automated Segmentability Index for Layer Segmentation of Macular SD-OCT Images

    NARCIS (Netherlands)

    Lee, K.; Buitendijk, G.H.; Bogunovic, H.; Springelkamp, H.; Hofman, A.; Wahle, A.; Sonka, M.; Vingerling, J.R.; Klaver, C.C.W.; Abramoff, M.D.

    2016-01-01

    PURPOSE: To automatically identify which spectral-domain optical coherence tomography (SD-OCT) scans will provide reliable automated layer segmentations for more accurate layer thickness analyses in population studies. METHODS: Six hundred ninety macular SD-OCT image volumes (6.0 x 6.0 x 2.3 mm3)

  12. Proxy support for service discovery using mDNS/DNS-SD in low power networks

    NARCIS (Netherlands)

    Stolikj, M.; Verhoeven, R.; Cuijpers, P.J.L.; Lukkien, J.J.

    2014-01-01

    We present a solution for service discovery of resource constrained devices based on mDNS/DNS-SD. We extend the mDNS/DNS-SD service discovery protocol with support for proxy servers. Proxy servers temporarily store information about services offered on resource constrained devices and respond on

  13. HOW TO MAKE A SINGLETON sdB STAR VIA ACCELERATED STELLAR EVOLUTION

    International Nuclear Information System (INIS)

    Clausen, Drew; Wade, Richard A.

    2011-01-01

    Many hot subdwarf B stars (sdBs) are in close binaries, and the favored formation channels for subdwarfs rely on mass transfer in a binary system to strip a core He-burning star of its envelope. However, these channels cannot account for sdBs that have been observed in long-period binaries nor the narrow mass distribution of isolated (or 'singleton') sdBs. We propose a new formation channel involving the merger of a helium white dwarf and a low-mass, hydrogen-burning star, which addresses these issues. Hierarchical triples whose inner binaries merge and form sdBs by this process could explain the observed long-period subdwarf+main-sequence binaries. This process would also naturally explain the observed slow rotational speeds of singleton sdBs. We also briefly discuss the implications of this formation channel for extreme horizontal branch morphology in globular clusters and the UV upturn in elliptical galaxies.

  14. Survival of free and microencapsulated human-derived oral probiotic Lactobacillus paracasei SD1 in orange and aloe vera juices

    Directory of Open Access Journals (Sweden)

    Rawee Teanpaisan

    2015-06-01

    Full Text Available Microencapsulation was evaluated as a means of preserving Lactobacillus paracasei SD1, a human-derived strain with probiotic potential, in orange and aloe vera juices. The microencapsulation parameters included alginate concentration, calcium chloride concentration and hardening-time, and the efficacy of microencapsulation to preserve the survival of microencapsulated bacteria compared to free cells during exposure in fruit juices were determined. The results revealed that the viable count of free-cell form markedly decreased compared to microencapsulated form. The microencapsulation of 2% alginate (w/v and 0.05 M CaCl2 gave the best result to preserve the probiotic. It was found that viability of microencapsulated probiotic bacteria was significantly higher than free-cell in fruit juices during 8 weeks of storage time in the refrigerator. The potential probiotic trait related to inhibitory effect was not affected after microencapsulation process. In summary, the microencapsulation method may be an alternative way of preserving the viability of probiotic L. paracasei SD1.

  15. Delay-controlled primary and stochastic resonances of the SD oscillator with stiffness nonlinearities

    Science.gov (United States)

    Yang, Tao; Cao, Qingjie

    2018-03-01

    This work presents analytical studies of the stiffness nonlinearities SD (smooth and discontinuous) oscillator under displacement and velocity feedback control with a time delay. The SD oscillator can capture the qualitative characteristics of quasi-zero-stiffness and negative-stiffness. We focus mainly on the primary resonance of the quasi-zero-stiffness SD oscillator and the stochastic resonance (SR) of the negative-stiffness SD oscillator. Using the averaging method, we have been analyzed the amplitude response of the quasi-zero-stiffness SD oscillator. In this regard, the optimum time delay for changing the control intensity according to the optimization standard proposed can be obtained. For the optimum time delay, increasing the displacement feedback intensity is advantageous to suppress the vibrations in resonant regime where vibration isolation is needed, however, increasing the velocity feedback intensity is advantageous to strengthen the vibrations. Moreover, the effects of time-delayed feedback on the SR of the negative-stiffness SD oscillator are investigated under harmonic forcing and Gaussian white noise, based on the Langevin and Fokker-Planck approaches. The time-delayed feedback can enhance the SR phenomenon where vibrational energy harvesting is needed. This paper established the relationship between the parameters and vibration properties of a stiffness nonlinearities SD which provides the guidance for optimizing time-delayed control for vibration isolation and vibrational energy harvesting of the nonlinear systems.

  16. Close-In Substellar Companions and the Formation of sdB-Type Close Binary Stars

    Directory of Open Access Journals (Sweden)

    L. Y. Zhu

    2015-02-01

    Full Text Available The sdB-type close binaries are believed to have experienced a common-envelope phase and may evolve into cataclysmic binaries (CVs. About 10% of all known sdB binaries are eclipsing binaries consisting of very hot subdwarf primaries and low-mass companions with short orbital periods. The eclipse profiles of these systems are very narrow and deep, which benefits the determination of high precise eclipsing times and makes the detection of small and close-in tertiary bodies possible. Since 2006 we have monitored some sdB-type eclipsing binaries to search for the close-in substellar companions by analyzing the light travel time effect. Here some progresses of the program are reviewed and the formation of sdB-type binary is discussed.

  17. Transcriptional analysis of heterologous gene expression using the endogenous sD promoter from Bacillus halodurans

    CSIR Research Space (South Africa)

    Crampton, Michael C

    2010-07-01

    Full Text Available This presentation focused on the transcriptional analysis of heterologous gene expression using the endogenous sD promoter from Bacillus halodurans. It concludes to a successful implementation of a high throughput mRNA sandwich hybridisation...

  18. Role of antisymmetric spin-orbit component in effective interactions in the sd-shell

    International Nuclear Information System (INIS)

    Yoshinada, K.

    1981-10-01

    The antisymmetric spin-orbit interaction (ALS) proposed for sd-shell nuclei is investigated. It is shown that the centroid energy of the d sub(5/2) - d sub(3/2) interactions plays a crucial role in reproducing the excited band spectra of A = 18 - 24 nuclei. An empirical effective interaction without ALS component is proposed to reproduce the observed spectra of light sd-shell nuclei. (author)

  19. An evaluation of the SD Bioline HIV/syphilis duo test.

    Science.gov (United States)

    Holden, Jeffrey; Goheen, Joshua; Jett-Goheen, Mary; Barnes, Mathilda; Hsieh, Yu-Hsiang; Gaydos, Charlotte A

    2018-01-01

    Many health agencies now recommend routine HIV and syphilis testing for pregnant women and most-at-risk populations such as men who have sex with men. With the increased availability of highly sensitive, low cost rapid point-of-care tests, the ability to meet those recommendations has increased, granting wider access to quick and accurate diagnoses. Using blood specimens collected from a Baltimore City Health Department (BCHD) sexually transmitted infection clinic, we evaluated the SD Bioline HIV/Syphilis Duo, a rapid test that simultaneously detects antibodies to HIV and syphilis and has the potential to further benefit clinics and patients by reducing costs, testing complexity, and patient wait times. SD DUO HIV sensitivity and specificity, when compared to BCHD results, were 91.7 and 99.5%, respectively. SD DUO syphilis sensitivity and specificity, when compared to rapid plasma reagin, were 85.7 and 96.8%, respectively, and 69.7 and 99.7%, respectively, when compared to Treponema pallidum particle agglutination (TPPA). SD DUO syphilis sensitivity and specificity, when compared to a traditional screening algorithm, improved to 92.3 and 100%, respectively, and improved to 72.9 and 99.7%, respectively, when compared to a reverse screening algorithm. The HIV component of the SD DUO performed moderately well. However, results for the SD DUO syphilis component, when compared to TPPA, support the need for further testing and assessment.

  20. Experimental Evaluation of the Pathogenicity of Different Strains of Schistosoma mansoni

    Directory of Open Access Journals (Sweden)

    Antônio Aurélio Euzébio

    2012-01-01

    Full Text Available The pathogenesis of three different Schistosoma mansoni strains from the Brazilian states of Minas Gerais (BH strain and São Paulo (SJ and SD strains was evaluated in experimentally infected mice. Observations of the most severe clinical cases among local patients treated (SD strain in the city of Campinas (São Paulo, Brazil formed the basis of this study. Mice were used as definitive hosts and were infected with cercariae from Biomphalaria tenagophila (SJ and SD strains and Biomphalaria glabrata (BH strains. The parameters analyzed were as follows: number of S. mansoni eggs in mice feces; number of granulomas per tissue area in liver, spleen, lungs, pancreas, and ascending colon; measurements of hepatic and intestinal granulomas; number of adult worms; and measurements of trematode eggs. The comparison among the three strains indicated that the SD strain, isolated in Campinas, presented a higher worm recovery relative to the number of penetrating cercariae. In addition, when compared to the SJ and BH strains, the SD strain demonstrated similar pathogenicity to the BH strain, with a greater quantity of granulomas in the viscera, as well as larger granulomas and eggs. Furthermore, a greater quantity of trematode eggs was also shed in the feces.

  1. Molecular characterization and specific detection of Anaplasma species (AP-sd) in sika deer and its first detection in wild brown bears and rodents in Hokkaido, Japan.

    Science.gov (United States)

    Moustafa, Mohamed Abdallah Mohamed; Lee, Kyunglee; Taylor, Kyle; Nakao, Ryo; Sashika, Mariko; Shimozuru, Michito; Tsubota, Toshio

    2015-12-01

    A previously undescribed Anaplasma species (herein referred to as AP-sd) has been detected in sika deer, cattle and ticks in Japan. Despite being highly similar to some strains of A. phagocytophilum, AP-sd has never been detected in humans. Its ambiguous epidemiology and the lack of tools for its specific detection make it difficult to understand and interpret the prevalence of this Anaplasma species. We developed a method for specific detection, and examined AP-sd prevalence in Hokkaido wildlife. Our study included 250 sika deer (Cervus nippon yesoensis), 13 brown bears (Ursus arctos yesoensis) and 252 rodents including 138 (Apodemus speciosus), 45 (Apodemus argenteus), 42 (Myodes rufocanus) and 27 (Myodes rutilus) were collected from Hokkaido island, northern Japan, collected during 2010 to 2015. A 770 bp and 382 bp segment of the 16S rRNA and gltA genes, respectively, were amplified by nested PCR. Results were confirmed by cloning and sequencing of the positive PCR products. A reverse line blot hybridization (RLB) based on the 16S rRNA gene was then developed for the specific detection of AP-sd. The prevalence of AP-sd by nested PCR in sika deer was 51% (128/250). We detected this Anaplasma sp. for the first time in wild brown bears and rodents with a prevalence of 15% (2/13) and 2.4% (6/252), respectively. The sequencing results of the 16S rRNA and gltA gene amplicons were divergent from the selected A. phagocytophilum sequences in GenBank. Using a newly designed AP-sd specific probe for RLB has enabled us to specifically detect this Anaplasma species. Besides sika deer and cattle, wild brown bears and rodents were identified as potential reservoir hosts for AP-sd. This study provided a high throughput molecular method that specifically detects AP-sd, and which can be used to investigate its ecology and its potential as a threat to humans in Japan. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. PENYELENGGARAAN PROGRAN SD-SMP SATU ATAP DALAM LATAR BUDAYA RUMAH BETANG KALIMANTAN TENGAH

    Directory of Open Access Journals (Sweden)

    Rudi Hasan

    2014-06-01

    Abstrak: Penyelenggaraan Progran SD-SMP Satu Atap dalam Latar Budaya Rumah Betang Kali­mantan Tengah. Penelitian ini bertujuan untuk mendeskripsikan penyelengaaraan program SD-SMP Satu Atap dalam latar budaya rumah Betang Kalimantan Tengah yang dikaitkan dengan struktur birokrasi, sumber daya, dan komunikasi. Penelitian kualitatif dilaksanakan di tiga lokasi, yaitu pada SMPN Satu Atap 1 Mihing Raya, SMPN Satu Atap 2 Kurun, dan SMPN Satu Atap 3 Tewah di Kabupaten Gunung Mas, Propinsi Kalimantan Tengah. Hasil penelitian menunjukkan bahwa acuan standar yang jelas, koordinasi yang intensif, dan pemberdayaan sumber daya manusia yang tepat sesuai dengan pendekatan nilai-nilai budaya rumah Betang dapat mencapai penyelenggaraan program SD-SMP Satu Atap yang efektif. Hal itu juga didukung oleh pengelolaan sumberdaya dan komunikasi yang mendasarkan diri pada nilai kekeluargaan, kebersamaan, loyalitas, dan keakraban.

  3. TEKNIK DAN STRATEGI TINDAK KESANTUNAN DIREKTIF DI KALANGAN ANDIK SD BERLATAR BELAKANG BUDAYA JAWA

    Directory of Open Access Journals (Sweden)

    Harun Joko Prayitno

    2011-12-01

    Full Text Available Studi ini bertujuan untuk merumuskan taksonomi tindak kesantunan direktif dikalangan andik SD yang berlatar belakang budaya Jawa. Tujuan spesifik studi iniadalah untuk merumuskan taksonomi dan pola semestaan realisasi tindakkesantunan direktif andik SD dalam hubungannya dengan prinsip dasar berbahasa PKS dan PSS; prinsip harmoni sosial PI dan PK. Objek penelitian ini adalah skala kelangsungan dan peringkat tindak kesantunandirektif dalam kaitannya PKS, PSS, prinsip harmoni sosial PI, PK, dn prinsip kultural budaya Jawa. Sumber data penelitian meliputi keseluruhan aktivitas berbahasa andik SD yang direfleksikan oleh guru kelas SD melalui FGD, baik dalam suasana formal maupun nonformal. Data penelitian berupa skala kelangsungan dan peringkat kesantunan pertuturan menurut PKS, PSS, PI, PK, dan Pk. Interpretasi perwujudan tindak kesantunan direktif dilakukan dengan kerja analisis pragmatik yang mengacu pada analisis heuristik model Grice, skala kelangsungan dan peringkat kesantunan model BrownLevinson. Hasil studi ini menunjukkan bahwa (1 perwujudan tindak kesantunan direktif (TKD di kalangan andik SD berlatar belakang budaya Jawa berkecenderungan diwujudkan melaui tipe menyuruh pada kategori memerintah dan tipe meminta pada kategori memohon. Temuan ini menggambarkah bahwa sesuai dengan kodratnya sebagai anak pada dasarnya masih memerlukan suri tauladan dari orang tuanya di rumah, gurunya di sekolah, dan panutannya sebagai yang difigurkan atau ditokohkan di lingkungan masyarakatnya masing-masing. (2 realisasi TKD di kalangan andik SD berlatar belakang budaya Jawa berkecenderungan dinyatakan dengan cara-cara tak langsung dan modus-modus nonliteral daripada dengan cara-cara langsung atau modus literal. Realisasi ini menggambarkan bahwa andik SD pada hakikatnya masih dalam masa perkembangan mental lingual sehingga masih memerlukan bimbingan yang bernilai positif, santun, dan berkarakter dari orang tua, guru, dan lingkungan

  4. MR imaging pulse sequence rationale: SD-, T1-, and T2-weighted images

    International Nuclear Information System (INIS)

    Sax, S.; Weathers, S.W.; Schneiders, N.J.; Horowitz, B.L.; Mawad, M.E.; Sandlin, M.E.; Blackwell, R.; Bryan, R.N.

    1986-01-01

    Over 500 patients have been examined with a pulse sequence designed to provide spin-density (SD)-weighted images (TR=3 sec, TE=35 msec), T1-weighted images (TR=0.3 sec, TE=35msec), and T2-weighted images (TR=3 sec, TE=105 msec) from which calculated ''synthesized'' images and SD, T1, and T2 calculated images could be obtained. Each image contributes unique information. SD-weighted images optimally display anatomy and often best highlight pathology. T1-weighted images are critical in assessing cerebral hemorrhages. T2-weighted images best display most lesions, but yield incomplete information in 35% of cases. All three types of ''weighted'' images are necessary to optimally display anatomy and fully characterize a lesion. Computerized calculations and simulations suggest that no other combination of pulse sequences yields equal information for a given examination time

  5. Revisiting PSS and service design in the light of the SD-logic

    DEFF Research Database (Denmark)

    Costa, Nina; Patrício, Lia; Morelli, Nicola

    2016-01-01

    are only means to an end. Also, different approaches, methods and tools have been developed to design value propositions however they still lack to explicit the SDlogic principles. The design of solutions that provide value-in-use is at the centre of both Product Service System (PSS) approach and service...... comprehensive discussion about these two approaches and proposes a conceptual framework for integrating PSS organizational point of view; and SD human-centred focus to design better service.......Researchers and practitioners have increasingly recognized the importance of offering value propositions to customers that enable value co-creation as discussed in the service dominant logic (SD-logic). SD-logic recognizes customers as active co-creators and posits that products and services...

  6. The Revitalization of Women’s Entrepreneurship Spirit In Micro Enterprises With Islamic Microfinance Institution (IMI (Study on The Contribution of BMTs Agam Madani in Agam sub-province, West Sumatra

    Directory of Open Access Journals (Sweden)

    Hesi Eka Puteri

    2014-03-01

    Full Text Available Objective - The objective of this paper is to give an overview of the contribution of Islamic Microfinance Institutions (IMI in the process of empowerment of women microenterprises, and recommended a related policy.Method – This study is a field research in 2012, which focused in BMTs Agam Madani at Agam district. The data is sourced from the observation, documentation and questionnaires from 60 women micro-entrepreneurs samples who receive working capital financing. This paper uses simple regression model in order to observe relationship between working capital and the increasing of revenue. This model is to measure the amount of the multiplier effect in working capital-to increasing of revenue.Result – This paper found that IMI is a good model to develop society more prosperous by developing BMTs in each district. These BMT has thousands of micro enterprises member and could revitalized the spirit of entrepreneurship of minangkabau’s women. A research to 60 women’s micro entrepreneur samples showed the positive significant influence between lending to revenue. A multiplier effect equal to 0.068.The small number of multiplier effect implied that many factors determining their revenue, not lending only.Conclusion – This finding could explain that IMI could empower micro entrepreneur woman. This finding also recommend few strategies: 1 Revitalization of BMTs as micro catalyst by revitalization of structure of organization, products variation, human resource compentence, sharia monitoring, public cooperation and implementating local cultural value 2 Revitalization of government role as fasilitator, coordinator, initiator and mediator in developing micro sector. Keywords : Women’s Entrepreneurship, Micro Enterprises, Islamic Microfinance Institution, BMTs Agam Madani 

  7. From novel mathematics to efficient algorithms. Do we have proper SD foundation to build future?

    Energy Technology Data Exchange (ETDEWEB)

    Tkachov, Fyodor V. [INR RAS, Moscow (Russian Federation)

    2002-08-01

    Computer implementation of sophisticated algorithms for physics applications is greatly facilitated by the new generation of component-oriented SD technologies pioneered by Wirth's Oberon and embraced by the software industry (Sun's Java and Microsoft's C no.). In a stark contrast with the deeply flawed C++, the Oberon technologies (specifically, the Component Pascal and the BlackBox development environment) offer an unparalleled SD platform for building scientific applications from sophisticated data processing to demanding symbolic calculations. Specific examples are discussed. (author)

  8. Microscopic descriptions of collective SD bands in the A=190 mass region with the Gogny force

    International Nuclear Information System (INIS)

    Girod, M.

    1997-01-01

    In the framework of microscopic models, we present two methods for describing superdeformed (SD) band properties. The first one is the cranked Hartree-Fock-Bogolyubov (HFB) method, without and with inclusion of particle number projection. The second one is the Gaussian overlap approximation to the generator coordinate method (GCM+GOA) with which we treat the five quadrupole collective coordinates. Both methods use the Gogny force. Moments of inertia and excitation energies of SD bands are calculated and compared with experimental results. (orig.). With 1 fig

  9. Nuclear structure of s-d shell nuclei: what is new?

    International Nuclear Information System (INIS)

    Shanmugam, G.

    1995-01-01

    In this paper the shape evolution of the even-even s-d shell nuclei with temperature and spin is studied using Landau theory of phase transitions. The most important thermal fluctuations are incorporated in this study. The ground state pairing is also included in the calculations. Both the summation and Strutinsky methods are used for extracting the Landau constants. Both yield qualitatively similar results. To conclude, Landau theory of phase transitions can be effectively and economically used to study the structure of excited s-d shell nuclei. 10 refs., 2 tabs., 8 figs

  10. The System Dynamics Model User Sustainability Explorer (SD-MUSE): a user-friendly tool for interpreting system dynamic models

    Science.gov (United States)

    System Dynamics (SD) models are useful for holistic integration of data to evaluate indirect and cumulative effects and inform decisions. Complex SD models can provide key insights into how decisions affect the three interconnected pillars of sustainability. However, the complexi...

  11. Çocuklarda Öykülemenin Gelişimi ve Dilin Değerlendirilmesinde Kullanımı

    Directory of Open Access Journals (Sweden)

    Pelin Piştav Akmeşe

    2015-12-01

    Full Text Available Çocukların kendini ifade etmek için en sık kullandığı sözel dili ifade biçimlerinden biri öykülerdir. Çocuklar, oldukça erken yaşlarda öykü anlatma becerilerini kazanmaya başlamaktadır. Öyküleme analizi bize çocukların, dil alanlarına ait bilgileri nasıl biraraya getirdiği hakkında bilgi sağlamaktadır. Öyküleme, çocuklardaki gelişimsel ilerlemeyi açık bir şekilde gösterebileceğinden sözel dil gelişimini değerlendirmek için bir araç olarak kullanılabilmektedir. Öyküler, günlük konuşmalardan daha karmaşık dil yapısına sahip olduğu için öyküleme gelişiminin değerlendirilmesi ile gelecekteki dil gelişimi yordanabilmektedir. Aynı zamanda erken dönem öyküleme becerisi, gelecekteki akademik becerilerin yordayıcısıdır. Bu yüzden öyküleme, dili öğrenme problemi olan tüm okul çağındaki çocuklarda müdahale hedefleri arasında yer almalıdır. It is a narrative or a story that is one of the most common verbal language expressions, which children use very often to express themselves. Children start to acquire their ability to tell a story at early ages. A narrative analysis provides us with the information about how it combines the information of linguistic areas. A narrative shows clearly the developmental progress and can be used as a means of the evaluation of verbal linguistic development. The linguistic development in the future can be predicted with the evaluation of the narrative development because the narratives have more complex linguistic structures than the daily language. In addıtıon, early narrative skills are the predictors of the academic skills in the future. That’s why, the narrative should be one of the intervention targets in school-age children who have a difficulty in learning the language.

  12. Is sdLDL a valuable screening tool for cardiovascular disease in ...

    African Journals Online (AJOL)

    Radwa Momtaz Abdelsamie Zaki Khalil

    Lipoprotein Cholesterol; LDL I, large buoyant LDL; LDL II, intermediate density LDL; LDL III, smaller dense LDL; .... triglycerides >_150 mg, high density lipoprotein (HDL) <40 mg/dl in men ... sion of phenotype B.4,12 For a given triglyceride level, women were .... that sdLDL /LDL ratio is a very strong predictor of CHD in men;.

  13. 75 FR 31464 - Certification of the Attorney General; Shannon County, SD

    Science.gov (United States)

    2010-06-03

    ... DEPARTMENT OF JUSTICE Certification of the Attorney General; Shannon County, SD In accordance with... within the scope of the determinations of the Attorney General and the Director of the Census made under...., Attorney General of the United States. [FR Doc. 2010-13285 Filed 6-2-10; 8:45 am] BILLING CODE P ...

  14. Positron annihilation and pressure-induced electronic s-d transition

    International Nuclear Information System (INIS)

    McMahan, A.K.; Skriver, H.L.

    1985-06-01

    The polycrystalline, partial annihilation rates for positrons in compressed cesium have been calculated using the linear muffin-tin orbitals method. These results suggest that the pressure-induced electronic s-d transition in Cs should be directly observable by momentum sensitive positron annihilation experiments

  15. 76 FR 1985 - Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes

    Science.gov (United States)

    2011-01-12

    ... Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes AGENCY: Federal Aviation Administration (FAA..., at an average labor rate of $85 per work hour. Required parts cost about $10 per product. Based on.... The average labor rate is $85 per work-hour. Based on these figures, we estimate the cost of the AD on...

  16. Semi-automatic geographic atrophy segmentation for SD-OCT images.

    Science.gov (United States)

    Chen, Qiang; de Sisternes, Luis; Leng, Theodore; Zheng, Luoluo; Kutzscher, Lauren; Rubin, Daniel L

    2013-01-01

    Geographic atrophy (GA) is a condition that is associated with retinal thinning and loss of the retinal pigment epithelium (RPE) layer. It appears in advanced stages of non-exudative age-related macular degeneration (AMD) and can lead to vision loss. We present a semi-automated GA segmentation algorithm for spectral-domain optical coherence tomography (SD-OCT) images. The method first identifies and segments a surface between the RPE and the choroid to generate retinal projection images in which the projection region is restricted to a sub-volume of the retina where the presence of GA can be identified. Subsequently, a geometric active contour model is employed to automatically detect and segment the extent of GA in the projection images. Two image data sets, consisting on 55 SD-OCT scans from twelve eyes in eight patients with GA and 56 SD-OCT scans from 56 eyes in 56 patients with GA, respectively, were utilized to qualitatively and quantitatively evaluate the proposed GA segmentation method. Experimental results suggest that the proposed algorithm can achieve high segmentation accuracy. The mean GA overlap ratios between our proposed method and outlines drawn in the SD-OCT scans, our method and outlines drawn in the fundus auto-fluorescence (FAF) images, and the commercial software (Carl Zeiss Meditec proprietary software, Cirrus version 6.0) and outlines drawn in FAF images were 72.60%, 65.88% and 59.83%, respectively.

  17. Context based service discovery in unmanaged networks using MDNS/DNS-SD

    NARCIS (Netherlands)

    Stolikj, M.; Cuijpers, P.J.L.; Lukkien, J.J.; Buchina, N.; Bellido, F.J.; Vun, N.C.H.; Dolar, C.; Diaz-Sanchez, D.; Ling, W.-K.

    2016-01-01

    We propose an extension of the mDNS/DNS-SD service discovery protocol, which enables service clients to discover and select services based on their context. The extension improves scalability in large networks, which is of particular importance in future Internet of Things deployments.

  18. Peran modal sosial dalam implementasi konsep pemikiran Ki Hadjar Dewantara di SD Taman Muda Yogyakarta

    Directory of Open Access Journals (Sweden)

    Sukma Wijayanto

    2017-09-01

    Full Text Available Penelitian ini bertujuan untuk mendeskripsikan: (1 implementasi pendidikan Ki Hadjar Dewantara; dan (2 modal sosial di SD Taman Siswa Jetis. Penelitian menggunakan pendekatan kualitatif dengan jenis penelitian studi kasus. Unit analisis penelitian adalah SD Tamansiswa Jetis. Penentuan subjek dalam penelitian ini menggunakan teknik purposive sampling dengan subjek penelitian adalah pamong, kepala sekolahdan ketua yayasan Majelis Luhur Persatuan Tamansiswa cabang Jetis. Teknik pengumpulan data menggunakan observasi partisipatif, wawancara dan dokumentasi. Teknik analisis penelitian ini menggunakan model interaktif Milles & Huberman. Berdasarkan penelitian diperoleh sebagai berikut: (1 Konsep pemikiran Ki Hadjar terlaksana di SD Taman Siswa Jetis yakni sistem among tidak dapat dipisahkan prinsip kemerdekaan dan kodrat alam. Pelaksanaan sistem among dilaksanakan dengan keteladanan, pembiasaan, pengajaran, serta hukumam, paksaan dan perintah. (2 Trust, Jaringan, dan norm dalam melaksanakan konsep Ki Hadjar Dewantara menggunakan nilai-nilai kekeluargaan. Kekeluargaan modal sosial yang menjadi kekuatan dalam melaksanakan konsep pendidikan Ki Hadjar di SD Taman Siswa Jetis.Kata kunci: Ki Hadjar Dewantara, Konsep Pendidikan Ki Hadjar Dewantara, Modal Sosial

  19. EVALUASI IMPLEMENTASI TQM PADA SDN KARANGREJEK II DAN SD MUHAMMADIYAH AL MUJAHIDIN WONOSARI GUNUNGKIDUL

    Directory of Open Access Journals (Sweden)

    Eko Pramono

    2015-10-01

    Full Text Available Penelitian ini bertujuan mengetahui: (1 seberapa besar tingkat implementasi TQM, (2 perbandingan implementasi, (3 aspek-aspek yang perlu mendapatkan perbaikan untuk ditingkatkan. Penelitian evaluasi dengan model descrepancy. Instrumen pengumpul data berupa angket jawaban skala 2 terdiri atas 69 butir. Teknik analisis data menggunakan teknik persentase. Hasil penelitian menunjukkan bahwa: (1 implementasi TQM di SD Negeri Karangrejek II rata-rata sebesar 87,73%, aspek-aspek yang mendekati standar: mutu pembelajaran, organisasi terbalik, perubahan kultur, kolega sebagai pelanggan, profesionalisme, dan pemasaran internal. Implementasi TQM di SD Muhammadiyah Al Mujahidin rata-rata sebesar 94,42%. Aspek-aspek yang mendekati standar: organisasi terbalik, mutu pembelajaran, perubahan kultur, profesionalisme, kaizen dan menjaga hubungan dengan pelanggan. (2 Perbandingan implementasi TQM sebagai berikut: aspek mutu pembelajaran, organisasi terbalik dan perubahan kultur merupakan aspek dengan rata-rata tertinggi di SD Karangrejek II, sedangkan di SD Muhammadiyah Al Mujahidin: aspek organisasi terbalik, mutu pembelajaran, dan perubahan kultur. (3 Aspek yang perlu mendapatkan perbaikan di kedua sekolah adalah perbaikan terus-menerus.

  20. Learning from CDM SD tool experience for Article 6.4 in the Paris Agreement

    DEFF Research Database (Denmark)

    Olsen, Karen Holm; Arens, Christof; Mersmann, Florian

    2017-01-01

    The Paris Agreement (PA) emphasizes the intrinsic relationship between climate change and sustainable development (SD) and welcomes the 2030 agenda for the global Sustainable Development Goals (SDGs). Yet, there is a lack of assessment approaches to ensure that climate and development goals...

  1. Canister storage building compliance assessment SNF project NRC equivalency criteria - HNF-SD-SNF-DB-003

    International Nuclear Information System (INIS)

    BLACK, D.M.

    1999-01-01

    This document presents the Project's position on compliance with the SNF Project NRC Equivalency Criteria - HNF-SD-SNF-DE-003, Spent Nuclear Fuel Project Path Forward Additional NRC Requirements. No non-compliances are shown. The compliance statements have been reviewed and approved by DOE. Open items are scheduled to be closed prior to project completion

  2. An Atlantic streamer in stratospheric ozone observations and SD-WACCM simulation data

    Science.gov (United States)

    Hocke, Klemens; Schranz, Franziska; Maillard Barras, Eliane; Moreira, Lorena; Kämpfer, Niklaus

    2017-03-01

    Observation and simulation of individual ozone streamers are important for the description and understanding of non-linear transport processes in the middle atmosphere. A sudden increase in mid-stratospheric ozone occurred above central Europe on 4 December 2015. The GROund-based Millimeter-wave Ozone Spectrometer (GROMOS) and the Stratospheric Ozone MOnitoring RAdiometer (SOMORA) in Switzerland measured an ozone enhancement of about 30 % at 34 km altitude (8.3 hPa) from 1 to 4 December. A similar ozone increase is simulated by the Specified Dynamics Whole Atmosphere Community Climate (SD-WACCM) model. Further, the global ozone fields at 34 km altitude (8.3 hPa) from SD-WACCM and the satellite experiment Aura/MLS show a remarkable agreement for the location and timing of an ozone streamer (large-scale tongue-like structure) extending from the subtropics in northern America over the Atlantic to central Europe. This agreement indicates that SD-WACCM can inform us about the wind inside the Atlantic ozone streamer. SD-WACCM shows an eastward wind of about 100 m s-1 inside the Atlantic streamer in the mid-stratosphere. SD-WACCM shows that the Atlantic streamer flows along the edge of the polar vortex. The Atlantic streamer turns southward at an erosion region of the polar vortex located above the Caspian Sea. The spatial distribution of stratospheric water vapour indicates a filament outgoing from this erosion region. The Atlantic streamer, the polar vortex erosion region and the water vapour filament belong to the process of planetary wave breaking in the so-called surf zone of the northern midlatitude winter stratosphere.

  3. Involvement of Fenton chemistry in rice straw degradation by the lignocellulolytic bacterium Pantoea ananatis Sd-1.

    Science.gov (United States)

    Ma, Jiangshan; Zhang, Keke; Huang, Mei; Hector, Stanton B; Liu, Bin; Tong, Chunyi; Liu, Qian; Zeng, Jiarui; Gao, Yan; Xu, Ting; Liu, Ying; Liu, Xuanming; Zhu, Yonghua

    2016-01-01

    Lignocellulolytic bacteria have revealed to be a promising source for biofuel production, yet the underlying mechanisms are still worth exploring. Our previous study inferred that the highly efficient lignocellulose degradation by bacterium Pantoea ananatis Sd-1 might involve Fenton chemistry (Fe 2+  + H 2 O 2  + H +  → Fe 3+  + OH· + H 2 O), similar to that of white-rot and brown-rot fungi. The aim of this work is to investigate the existence of this Fenton-based oxidation mechanism in the rice straw degradation process of P. ananatis Sd-1. After 3 days incubation of unpretreated rice straw with P. ananatis Sd-1, the percentage in weight reduction of rice straw as well as its cellulose, hemicellulose, and lignin components reached 46.7, 43.1, 42.9, and 37.9 %, respectively. The addition of different hydroxyl radical scavengers resulted in a significant decline ( P  Fenton reagent treatment. In addition to the increased total iron ion concentration throughout the rice straw decomposition process, the Fe 3+ -reducing capacity of P. ananatis Sd-1 was induced by rice straw and predominantly contributed by aromatic compounds metabolites. The transcript levels of the glucose-methanol-choline oxidoreductase gene related to hydrogen peroxide production were significantly up-regulated (at least P  Fenton-like reactions. Our results confirmed the Fenton chemistry-assisted degradation model in P. ananatis Sd-1. We are among the first to show that a Fenton-based oxidation mechanism exists in a bacteria degradation system, which provides a new perspective for how natural plant biomass is decomposed by bacteria. This degradative system may offer an alternative approach to the fungi system for lignocellulosic biofuels production.

  4. Test characteristics of two rapid antigen detection tests (SD FK50 and SD FK60 for the diagnosis of malaria in returned travellers

    Directory of Open Access Journals (Sweden)

    Van Esbroeck Marjan

    2009-05-01

    Full Text Available Abstract Background Two malaria rapid diagnostic tests were evaluated in a travel clinic setting: the SD FK50 Malaria Ag Plasmodium falciparum test (a two-band test and the SD FK60 Malaria Ag P. falciparum/Pan test (a three-band test. Methods A panel of stored whole blood samples (n = 452 and n = 614 for FK50 and FK60, respectively from returned travellers was used. The reference method was microscopy with PCR in case of discordant results. Results For both tests, overall sensitivity for the detection of P. falciparum was 93.5%, reaching 97.6% and 100% at parasite densities above 100 and 1,000/μl respectively. Overall sensitivities for Plasmodium vivax, Plasmodium ovale and Plasmodium malariae for the FK60 test were 87.5%, 76.3% and 45.2%, but they reached 92.6% and 90.5% for P. vivax and P. ovale at parasite densities above 500/μl. Specificities were above 95% for all species and both tests when corrected by PCR, with visible histidine-rich protein-2 lines for P. malariae (n = 3 and P. vivax and P. ovale (1 sample each. Line intensities were reproducible and correlated to parasite densities. The FK60 tests provided clues to estimate parasite densities for P. falciparum below or above 1,000/μl. Conclusion Both the FK50 and FK60 performed well for the diagnosis of P. falciparum in the present setting, and the FK60 for the diagnosis of P. vivax and P. ovale at parasite densities > 500/μl. The potential use of the FK60 as a semi-quantitative estimation of parasite density needs to be further explored.

  5. Fiscal 1999 achievement report on regional consortium research and development project. Regional consortium research and development of energy in its 2nd year (Development of energy conservation assisting measurement control technology for electronic equipment manufacturing process--Designing and tentative construction of IMI); 1999 nendo denshi kikirui seizo process no sho energy shien keisoku seigyo gijutsu no kaihatsu seika hokokusho. 2. IMI no sekkei to shisaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    In the research and development of IMI (intelligent micro instrument) substrate devices, a designing method is established and, using the method, device manufacturing technologies are tested and evaluated and the results are reflected on the experimental construction of a sensor and an IC probe. In the research and development of a sensor and a sensing system, efforts are focused on a chlorine gas sensor, and a prototype No. 1 is designed and fabricated. In a test conducted in the presence of gas of 0-10ppm concentration, the prototype transmits signals that indicate excellent linearity and responsiveness. In the research and development of a probe for measuring electronic devices, efforts are made to put to practical use an IC (integrated circuit) probe of 40{mu}m pitch times 400 arrays, and specifications to develop for the probe are defined. A tentatively built cantilever structure shows values that justify its practical application. In the research and development of an IMI electronic circuit, a prototype No. 1 of a system for processing and transmitting sensor signals by radio is manufactured, which operates on the carrier frequency of 2.4GHz and sampling frequency of 4kHz. The prototype performs to achieve the goal. (NEDO)

  6. Critical current oscillations in S/F heterostructures in the presence of s-d scattering

    International Nuclear Information System (INIS)

    Vedyayev, A.V.; Ryzhanova, N.V.; Pugach, N.G.

    2006-01-01

    Josephson current is investigated in the superconductor/ferromagnet/superconductor junction. It was shown that the current exhibited damping oscillations as a function of the ferromagnetic layer thickness. Previous theories based on Usadel or Eilenberger equations have predicted that the damping length and oscillation period divided by 2π were the same for weak ferromagnetic spacer. This contradicts past experiments. A new calculation of the Josephson current is proposed. The Gorkov equations are solved taking into account s-d scattering in ferromagnet. It is shown that the oscillation period depends only on the exchange magnetic field in the spacer, whereas the damping length is connected to the ferromagnetic mean free path. The concordance with the former experiment allows one to conclude that s-d scattering as a pair-breaking mechanism plays a significant role in the proximity effect in S/F heterostructures

  7. Somatoform abdominal pain in surgery: is SD worthy of surgical attention? Case reports and literature review.

    LENUS (Irish Health Repository)

    Abd Elwahab, Sami Medani

    2012-08-01

    Somatoform disorders (SD) or medically unexplained physical symptoms (MUPS) are a group of disorders that represent a group of symptoms that cannot be explained by an organic or physical pathology. These disorders are widely prevalent, and, if unrecognised, SD may lead medical professionals to embark on tests or procedures which may inflict unnecessary iatrogenic complications. Despite the high prevalence, they are only poorly included in medical training curricula, at both undergraduate and postgraduate levels. In this article, we review the literature and present two cases. The first one presented with a recurrent acute abdomen had an unnecessary CT abdomen. The second case had laparoscopy for acute right-sided abdominal pain which turned out to be normal, and was readmitted again after a short period with acute urine retention which resolved spontaneously following discussion with the patient and family. Both cases were referred for psychiatric assessment and their family doctors were informed.

  8. Complex dynamics of an archetypal self-excited SD oscillator driven by moving belt friction

    International Nuclear Information System (INIS)

    Li Zhi-Xin; Cao Qing-Jie; Alain, Léger

    2016-01-01

    We propose an archetypal self-excited system driven by moving belt friction, which is constructed with the smooth and discontinuous (SD) oscillator proposed by the Cao et al. and the classical moving belt. The moving belt friction is modeled as the Coulomb friction to formulate the mathematical model of the proposed self-excited SD oscillator. The equilibrium states of the unperturbed system are obtained to show the complex equilibrium bifurcations. Phase portraits are depicted to present the hyperbolic structure transition, the multiple stick regions, and the friction-induced asymmetry phenomena. The numerical simulations are carried out to demonstrate the friction-induced vibration of multiple stick-slip phenomena and the stick-slip chaos in the perturbed self-excited system. The results presented here provide an opportunity for us to get insight into the mechanism of the complex friction-induced nonlinear dynamics in mechanical engineering and geography. (paper)

  9. Pengembangan Instrumen Penilaian Mapel Sains melalui Pendekatan Keterampilan Proses Sains SD/MI

    Directory of Open Access Journals (Sweden)

    Moh. Arif

    2016-06-01

    Full Text Available Penulisan artikel ini bertujuan untuk memberikan format pengembangan intrumen penilaian keterampilan proses sains SD yang masih menjadi problematika untuk menentukan pengembangan instrumen. Di samping itu, artikel ini ditulis untuk mengetahui karakteristik dan beberpa prosedur pelaksanaan penilaian proses sains SD dengan memberikan format pengembangan instrumen penialaian proses sains yang meliputi penyusunan rencana penelitian, penyusunan kisi-kisi, pembuatan soal sampai pada penganalisian butir soal. Konsep dasar penilaian yang perlu ditekankan adalah keefektivan instrumen penilaian, yang terdiri dari tiga unsur utama yakni valid (validity, reliabel (reliability, dan praktis (practicality. Berdasarkan tujuan dan perbedaan waktu pelaksanaanya, terdapat tiga jenis bentuk penilaian proses sains pada siswa Sekolah Dasar: Penilaian Diagnostik, Penilaian formatif dan Penilaian sumatif. Tes akan dianalisis secara kualitatif baik dari segi materi, konstruksi maupun bahasa. Analisis secara kuantitatif dengan pendekatan teori tes klasik yakni dengan Iteman dan analisis secara kuantitatif menggunakan pendekatan teori tes modern yakni program Bigstep.

  10. PELAKSANAAN PROGRAM PERILAKU HIDUP BERSIH DAN SEHAT (PUBS DI SD NEGERI 001 TANJUNG BALAI KARIMUN

    Directory of Open Access Journals (Sweden)

    Fivi Melva Diana

    2013-09-01

    Full Text Available Laporan Tahunan Tahun 2011 Dinas kesehatan Kabupaten Karimun, sekolah yang telah melaksanakan PHBS hanya 22,5% dengan target 65% sedangkan target nasional intitusi pendidikan yang melaksanakanPHBS adalah 70% ditahun 2014. Rendahnya cakupan ini berdampak juga terhadap tingginya angka kesakitan yang berhubungan dengan penyakit yang berorientasi lingkungan dan perilaku. Tujuan penelitian adalah mengetahui hubungan sikap, pengetahuan dan peran guru dengan pelaksanaan PHBS di SD negeri 001 Tanjung Balai Karimun Tahun 2013. Desain Crossectional Study, populasi adalah seluruh murid kelas IV, V dan IV, sedangkan sampel sebanyak 64 orang dan dibagi secara proporsionaluntuk masing-masingkelas. Data dikumpulkan melalui kuesioner, diolah dengan uji Chi-square. Darihasil uji statistik terdapat hubunganbermakna antara pengetahuan, dan peran guru dengan pelaksanan program PHBS pada anak sekolah di SD Negeri 001 Tanjung Balai Karimun Tahun 2013 (p>0,05.Disarankan untuk meningkatan pengetahuan melalui pelatihan, penyuluhan dan memperbanyak mediapromosi seperti poster, leaflet dll.

  11. Spectral analysis of the He-enriched sdO-star HD 127493

    Science.gov (United States)

    Dorsch, Matti; Latour, Marilyn; Heber, Ulrich

    2018-02-01

    The bright sdO star HD127493 is known to be of mixed H/He composition and excellent archival spectra covering both optical and ultraviolet ranges are available. UV spectra play a key role as they give access to many chemical species that do not show spectral lines in the optical, such as iron and nickel. This encouraged the quantitative spectral analysis of this prototypical mixed H/He composition sdO star. We determined atmospheric parameters for HD127493 in addition to the abundance of C, N, O, Si, S, Fe, and Ni in the atmosphere using non-LTE model atmospheres calculated with TLUSTY/SYNSPEC. A comparison between the parallax distance measured by Hipparcos and the derived spectroscopic distance indicate that the derived atmospheric parameters are realistic. From our metal abundance analysis, we find a strong CNO signature and enrichment in iron and nickel.

  12. Gene Profiling in Late Blight Resistance in Potato Genotype SD20

    Directory of Open Access Journals (Sweden)

    Xiaohui Yang

    2018-06-01

    Full Text Available Late blight caused by the oomycete fungus Phytophthora infestans (Pi is the most serious obstacle to potato (Solanum tuberosum production in the world. A super race isolate, CN152, which was identified from Sichuan Province, China, could overcome nearly all known late blight resistance genes and caused serious damage in China. The potato genotype SD20 was verified to be highly resistant to CN152; however, the molecular regulation network underlying late blight resistance pathway remains unclear in SD20. Here, we performed a time-course experiment to systematically profile the late blight resistance response genes using RNA-sequencing in SD20. We identified 3354 differentially expressed genes (DEGs, which mainly encoded transcription factors and protein kinases, and also included four NBS-LRR genes. The late blight responsive genes showed time-point-specific induction/repression. Multi-signaling pathways of salicylic acid, jasmonic acid, and ethylene signaling pathways involved in resistance and defense against Pi in SD20. Gene Ontology and KEGG analyses indicated that the DEGs were significantly enriched in metabolic process, protein serine/threonine kinase activity, and biosynthesis of secondary metabolites. Forty-three DEGs were involved in immune response, of which 19 were enriched in hypersensitive response reaction, which could play an important role in broad-spectrum resistance to Pi infection. Experimental verification confirmed the induced expression of the responsive genes in the late blight resistance signaling pathway, such as WRKY, ERF, MAPK, and NBS-LRR family genes. Our results provided valuable information for understanding late blight resistance mechanism of potato.

  13. Inversion for Eigenvalues and Modes Using Sierra-SD and ROL.

    Energy Technology Data Exchange (ETDEWEB)

    Walsh, Timothy [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Aquino, Wilkins [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ridzal, Denis [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kouri, Drew Philip [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-12-01

    In this report we formulate eigenvalue-based methods for model calibration using a PDE-constrained optimization framework. We derive the abstract optimization operators from first principles and implement these methods using Sierra-SD and the Rapid Optimization Library (ROL). To demon- strate this approach, we use experimental measurements and an inverse solution to compute the joint and elastic foam properties of a low-fidelity unit (LFU) model.

  14. Semi-automatic geographic atrophy segmentation for SD-OCT images

    OpenAIRE

    Chen, Qiang; de Sisternes, Luis; Leng, Theodore; Zheng, Luoluo; Kutzscher, Lauren; Rubin, Daniel L.

    2013-01-01

    Geographic atrophy (GA) is a condition that is associated with retinal thinning and loss of the retinal pigment epithelium (RPE) layer. It appears in advanced stages of non-exudative age-related macular degeneration (AMD) and can lead to vision loss. We present a semi-automated GA segmentation algorithm for spectral-domain optical coherence tomography (SD-OCT) images. The method first identifies and segments a surface between the RPE and the choroid to generate retinal projection images in wh...

  15. The threshold anomaly in the interaction of s-d shell nuclei

    International Nuclear Information System (INIS)

    Bilwes, B.

    1990-01-01

    The energy dependence of the potential near the Coulomb barrier is studied by precise measurements of elastic scattering and quasi elastic reactions between s-d shell nuclei. The analyses with semi-microscopic (M3Y-folding model) and microscopic (closure approximation model) potentials allow us to demonstrate the generality of the threshold anomaly and the ability of these models to well reproduce the experimental data

  16. PERAN ORANG TUA TERADAP PRESTASI BELAJAR SISWA SD AL-FURQAN JEMBER

    Directory of Open Access Journals (Sweden)

    Sofyan Rofi

    2016-04-01

    Full Text Available Objective of the study : (1 to know how far parents’ role student learning achievement at Al-furqan Jember, (2 how to correlation between parent of student and school at SD Al-Furqan Jember. This study was done at SD Al-Furqan Jember, by using qualitative approach. Data collecting technique was done by : (1 deep interview, (2 documentation. While checking up data validity was done by cross check with triangulation technique and colleagues discussion. Data analysis was done by (1 data reduction, (2 data presentation, (3 withdrawal of conclusion. From data analysis was found that parent has so central to student learning achievement, because education in school is still not enough increase student learning achievement. With the parents’ role so not just teacher wo strive to increase student learning achievement however parent does advising to their child by join the course. While relation between student old fellow with school intertwin intensive communications with meeting of pupil sponsor mothers in majelis ta’lim that conducted by institution of Al-Furqan Jember. From all data and the result of research finding is found that parents’ role is so necessary to student learning achievement of SD Al-Furqan Jember and relation among student old fellow with school is very good and communicative. As for researcher suggestion is school have to be more improve role of old fellow to student learning process, in order to student achievement progressively mount.       Key word : Parent, learning achievement

  17. IMPLEMENTASI KEPEMIMPINAN TRANSFORMASIONAL KEPALA SEKOLAH DALAM MENINGKATKAN MUTU SEKOLAH DI SD KANISIUS SENGKAN KABUPATEN SLEMAN

    Directory of Open Access Journals (Sweden)

    Tukiman Tukiman

    2014-10-01

    Full Text Available Penelitian ini bertujuan untuk mengungkapkan implementasi kepemimpinan transformasional kepala sekolah dalam meningkatkan mutu sekolah SD Kanisius Sengkan, Kabupaten Sleman. Penelitian ini merupakan penelitian kualitatif dengan jenis penelitian studi kasus. Pengumpulan data menggunakan metode kajian dokumen, observasi, dan wawancara. Analisis data menggunakan analisis model interaktif dari Miles dan Huberman yang meliputi empat tahap analisis yaitu: pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa kepemimpinan transformasional kepala sekolah SD Kanisius Sengkan mampu menciptakan perubahan dan membawa SD Kanisius mencapai prestasi yang baik. Kepala sekolah menjadi tokoh panutan yang dihormati, dihargai, dan dipercaya. Kepala sekolah mampu membangun semangat kebersamaan dan kedisiplinan serta memotivasi para guru dan karyawan untuk bekerja secara optimal. Kepala sekolah berani melakukan perubahan melalui tindakan-tindakan yang kreatif dan inovatif. Akhirnya kepala sekolah mampu membangun kesadaran berorganisasi pada para guru dan karyawan dengan mengembangkan sikap rasa memiliki dan rasa bertanggung jawab untuk meraih prestasi setinggi-tingginya.Kata kunci: kepala sekolah, kepemimpian transformasional, mutu sekolah.

  18. Fragmentation of stretched spin strength in N=Z sd-shell nuclei

    International Nuclear Information System (INIS)

    Carr, J.A.; Bloom, S.D.; Petrovich, F.; Philpott, R.J.

    1992-01-01

    Calculations have been performed to explore the effect of configuration mixing in a large basis on the fragmentation of ''stretched'' M6 strength in the sd-shell nuclei 20 Ne, 24 Mg, 28 Si, 32 S, and 36 Ar. This work elaborates on results for 28 Si given previously, extends those calculations to neighboring N=Z nuclei with the same basis restriction (one particle in the 1f 7/2 orbit and up to four particles in the 1d 3/2 orbit) used in that earlier paper, and examines all self-conjugate sd-shell nuclei in a basis with one particle in the 1f 7/2 orbit and unrestricted occupancy of the sd-shell orbits. It is found that configuration mixing in a large basis reproduces interesting features of the spectrum for 28 Si and 32 S and gives an improved description of other properties of the observed 6 - states, but fails to describe the observed spectrum in 24 Mg. Emphasis is placed on the location of additional observable fragments of the M6 response

  19. The Traffic Signal Acquisition System Based on GPS and SD Card Storage

    Directory of Open Access Journals (Sweden)

    LIU Chang-yuan

    2017-06-01

    Full Text Available In terms of the issues where traffic lights’ positions and traffic status information cannot be managed automatically,in this system,STC12C5A60S2 microcontroller can be used as the master chip in conjunction with the GPS position module,Neo-5Q. The wireless transceiver module,PT2262 /2272 and the portable installing SD card are used to design a new type of real-time information acquisition solution for positions of traffic lights and signal status. And the system can determine the traffic lights’ positions and the process of lighting in a real time. Then the data will be stored in SD card by the SD card module. Furthermore,the equipment can be implemented on existing facilities with a simple circuit. According to the result of experiments,the system contains a convenient storage,works in a real time and it is also advisable to help with the data reading and analysis. Thus, implementation of the system is of great significance to acquire and analyze the traffic status information in recent times.

  20. Multimodal segmentation of optic disc and cup from stereo fundus and SD-OCT images

    Science.gov (United States)

    Miri, Mohammad Saleh; Lee, Kyungmoo; Niemeijer, Meindert; Abràmoff, Michael D.; Kwon, Young H.; Garvin, Mona K.

    2013-03-01

    Glaucoma is one of the major causes of blindness worldwide. One important structural parameter for the diagnosis and management of glaucoma is the cup-to-disc ratio (CDR), which tends to become larger as glaucoma progresses. While approaches exist for segmenting the optic disc and cup within fundus photographs, and more recently, within spectral-domain optical coherence tomography (SD-OCT) volumes, no approaches have been reported for the simultaneous segmentation of these structures within both modalities combined. In this work, a multimodal pixel-classification approach for the segmentation of the optic disc and cup within fundus photographs and SD-OCT volumes is presented. In particular, after segmentation of other important structures (such as the retinal layers and retinal blood vessels) and fundus-to-SD-OCT image registration, features are extracted from both modalities and a k-nearest-neighbor classification approach is used to classify each pixel as cup, rim, or background. The approach is evaluated on 70 multimodal image pairs from 35 subjects in a leave-10%-out fashion (by subject). A significant improvement in classification accuracy is obtained using the multimodal approach over that obtained from the corresponding unimodal approach (97.8% versus 95.2%; p < 0:05; paired t-test).

  1. PENTINGNYA PENDIDIKAN ANTI KEKERASAN BAGI ANAK SD DALAM MEWUJUDKAN WARGA NEGARA YANG BAIK

    Directory of Open Access Journals (Sweden)

    Sigit dk

    2010-01-01

    Full Text Available Kekerasan  yang terjadi di Indonesia dari hari ke sehari angkanya semakin meningkat, kekerasan itu terjadi terhadap perempuan, anak-anak,  dan kekerasan  biasanya  lebih  banyak dalam rumah tangga (KDRT. Data yang dilansir Komnas Perempuan paska diundangkan UU-PKDRT tahun 2004 menunjukkan angka yang sangat memprihatinkan. Oleh karena itu masalah  kekerasan terhadap istri (KTI  tahun 2004 mencapai 1.782 kasus, sedang tahun 2005 terdapat 4.889 kasus, dan tahun 2007  mencapai 17.772 kasus  dan angka tersebut cenderung meningkat (Kedaulatan Rakyat 29 Nov. 2008; 1. Dalam peringatan 16 hari anti kekerasan terhadap perempuan yang dimulai tanggal 25 November 2008 sampai dengan 10 Desember 2008, hari AIDS 1 Desember dan hari Hak Azasi Manusia (HAM  jatuh  pada tanggal 10 Desember masih terdapat kekerasan masif,  dan agaknya bangsa ini perlu meratifikasi kembali pelbagai kekerasan yang terjadi di Indonesia. Kekerasan virtual juga disuguhkan di layar TV melalui film anak-anak seperti Naruto, Avatar dan media elektronika melalui komputer, geme onliene dan tersosialisasi pada anak-anak SD (Sekolah Dasar.  Akibatnya anak-anak SD akrab dengan kekerasan dan mengimplementasikan dalam bentuk perilaku yang distruktif. Melalui Pendidikan anti kekerasan diharapkan dapat memberikan secercah harapan agar generasi muda khususnya anak SD menjadi warga negara yang baik, cinta damai mengasihi sesama mengabdikan diri pada anti kekerasan.   Kata Kunci: Pendididikan, Kekerasan, Sekolah Dasar.

  2. PENGGUNAAN MEDIA ILUSTRASI POP-UP SEJARAH DALAM PEMBELAJARAN IPS DI SD NEGERI BATURSARI

    Directory of Open Access Journals (Sweden)

    Yulita Dewi Purmintasari

    2017-06-01

    Full Text Available This study aims: (1to know the process of learning social science in SD Negeri Batursari, (2 to know the use of illustration pop-up media in relieve the teacher to foster student‟s understanding toward the social science subject. This study was conducted in SD Negeri Batursari by using qualitative research strategies. The technique in collecting data were interview, direct observation, questionnaires and research document. The data validated by using triangulation researcher, theoretical and methodological. The technique using data collection, data reduction, and data presentation and conclusion/ verification. The result showed that fourth and rade students SD Negeri Batursari very anthusiastic in participating learning social science, students were formed into small groups and students talk to each other discussing visula messages in pop-up media. Illustration pop-up media is very helpful the teacher inleraning social science, it can be seen when students most easily to understand the material by looking at the illustration in the material. The syudents helped with the media as if the were in the illustration. Keywords: Pop-Up Media, Social Science Learning

  3. Penerapan Model Pembelajaran TPS Untuk Meningkatkan Hasil Belajar IPA Siswa Kelas V SD No 1 Mengwitani

    Directory of Open Access Journals (Sweden)

    I W Daniel Winantara

    2017-05-01

    Full Text Available Tujuan penelitian ini untuk mengetahui peningkatan hasil belajar IPA siswa kelas V SD No. 1 Mengwitani setelah diterapkannya model pembelajaran think pair share (TPS. Penelitian ini adalah penelitian tindakan kelas yang dilakukan dalam dua siklus. Subjek dalam penelitian ini adalah siswa kelas V yang berjumlah 32 orang. Data penelitian ini tentang hasil belajar yang dikumpulkan dengan menggunakan metode tes. Data dianalisis dengan menggunakan statistik kuantitatif. Hasil penelitian menunjukkan adanya peningkatan terhadap hasil belajar IPA siswa kelas V SD No. 1 Mengwitani. Hal ini ditunjukkan dengan hasil penelitian yang diperoleh yaitu persentase rata-rata hasil belajar pada siklus I sebesar 75,31% yang berada pada kategori sedang dan pada siklus II menjadi 80,15% yang berada pada kategori tinggi. Dengan ketuntasan belajar siswa pada siklus I sebesar 65,62% dan pada siklus II mencapai 87,5%. Berdasarkan hasil penelitian tersebut dapat disimpulkan penerapan model pembelajaran think pair share dapat meningkatkan hasil belajar IPA siswa kelas V SD No. 1 Mengwitani.

  4. Ultra-Widefield Steering-Based SD-OCT Imaging of the Retinal Periphery

    Science.gov (United States)

    Choudhry, Netan; Golding, John; Manry, Matthew W.; Rao, Rajesh C.

    2016-01-01

    Objective To describe the spectral-domain optical coherence tomography (SD-OCT) features of peripheral retinal findings using an ultra-widefield (UWF) steering technique to image the retinal periphery. Design Observational study. Participants 68 patients (68 eyes) with 19 peripheral retinal features. Main Outcome Measures SD-OCT-based structural features. Methods Nineteen peripheral retinal features including: vortex vein, congenital hypertrophy of the retinal pigment epithelium (CHRPE), pars plana, ora serrata pearl, typical cystoid degeneration (TCD), cystic retinal tuft, meridional fold, lattice and cobblestone degeneration, retinal hole, retinal tear, rhegmatogenous retinal detachment (RRD), typical degenerative senile retinoschisis, peripheral laser coagulation scars, ora tooth, cryopexy scars (retinal tear and treated retinoblastoma scar), bone spicules, white without pressure, and peripheral drusen were identified by peripheral clinical examination. Near infrared (NIR) scanning laser ophthalmoscopy (SLO) images and SD-OCT of these entities were registered to UWF color photographs. Results SD-OCT resolved structural features of all peripheral findings. Dilated hyporeflective tubular structures within the choroid were observed in the vortex vein. Loss of retinal lamination, neural retinal attenuation, RPE loss or hypertrophy were seen in several entities including CHRPE, ora serrata pearl, TCD, cystic retinal tuft, meridional fold, lattice and cobblestone degenerations. Hyporeflective intraretinal spaces, indicating cystoid or schitic fluid, were seen in ora serrata pearl, ora tooth, TCD, cystic retinal tuft, meridional fold, retinal hole, and typical degenerative senile retinoschisis. The vitreoretinal interface, which often consisted of lamellae-like structures of the condensed cortical vitreous near or adherent to the neural retina, appeared clearly in most peripheral findings, confirming its association with many low-risk and vision-threatening pathologies

  5. SD-EAR: Energy Aware Routing in Software Defined Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Anuradha Banerjee

    2018-06-01

    Full Text Available In today’s internet-of-things (IoT environment, wireless sensor networks (WSNs have many advantages, with broad applications in different areas including environmental monitoring, maintaining security, etc. However, high energy depletion may lead to node failures in WSNs. In most WSNs, nodes deplete energy mainly because of the flooding and broadcasting of route-request (RREQ packets, which is essential for route discovery in WSNs. The present article models wireless sensor networks as software-defined wireless sensor networks (SD-WSNs where the network is divided into multiple clusters or zones, and each zone is controlled by a software-defined network (SDN controller. The SDN controller is aware of the topology of each zone, and finds out the optimum energy efficient path from any source to any destination inside the zone. For destinations outside of the zone, the SDN controller of the source zone instructs the source to send a message to all of the peripheral nodes in that zone, so that they can forward the message to the peripheral nodes in other zones, and the process goes on until a destination is found. As far as energy-efficient path selection is concerned, the SDN controller of a zone is aware of the connectivity and residual energy of each node. Therefore, it is capable of discovering an optimum energy efficient path from any source to any destination inside as well as outside of the zone of the source. Accordingly, flow tables in different routers are updated dynamically. The task of route discovery is shifted from individual nodes to controllers, and as a result, the flooding of route-requests is completely eliminated. Software-defined energy aware routing (SD-EARalso proposes an innovative sleeping strategy where exhausted nodes are allowed to go to sleep through a sleep request—sleep grant mechanism. All of these result in huge energy savings in SD-WSN, as shown in the simulation results.

  6. Color suppressed contributions to the decay modes B{sub d,s}{yields}D{sub s,d}D{sub s,d}, B{sub d,s}{yields}D{sub s,d}D{sup *}{sub s,d}, and B{sub d,s}{yields}D{sup *}{sub s,d} D{sup *}{sub s,d}

    Energy Technology Data Exchange (ETDEWEB)

    Eeg, J.O. [University of Oslo, Department of Physics, Blindern, Oslo (Norway); Fajfer, S. [University of Ljubljana, Department of Physics, Ljubljana (Slovenia); J. Stefan Institute, Ljubljana (Slovenia); Prapotnik, A. [J. Stefan Institute, Ljubljana (Slovenia)

    2005-07-01

    The amplitudes for decays of the type B{sub d,s}{yields}D{sub s,d}D{sub s,d}, have no factorizable contributions, while B{sub d,s}{yields}D{sub s,d}D{sup *}{sub s,d}, and B{sub d,s}{yields}D{sup *}{sub s,d}D{sup *}{sub s,d} have relatively small factorizable contributions through the annihilation mechanism. The dominant contributions to the decay amplitudes arise from chiral loop contributions and tree level amplitudes which can be obtained in terms of soft gluon emissions forming a gluon condensate. We predict that the branching ratios for the processes anti B{sup 0}{sub d}{yields}D{sub s}{sup +}D{sub s}{sup -}, anti B{sup 0}{sub d}{yields}D{sub s}{sup +*} D{sub s}{sup -} and anti B{sup 0}{sub d}{yields}D{sub s}{sup +}D{sub s}{sup -*} are all of order (2-3) x 10{sup -4}, while anti B{sup 0}{sub s}{yields}D{sub d}{sup +}D{sub d}{sup -}, anti B{sup 0}{sub s}{yields}D{sub d}{sup +*}D{sub d}{sup -} and anti B{sup 0}{sub s}{yields}D{sub d}{sup +}D{sub d}{sup -*} are of order (4-7) x 10{sup -3}. We obtain branching ratios for two D{sup *}'s in the final state of order two times bigger. (orig.)

  7. The NFI TOKAI SD System - management of the capabilities of operators in fuel fabrication plants

    International Nuclear Information System (INIS)

    Fukushima, T.

    2008-01-01

    Since the JCO criticality accident occurred in 1999, even more emphasis has been placed on the management of nuclear safety in Japan. This is particularly true for the education of operators and the observance of operational procedures. Even prior to this accident, Nuclear Fuel Industries, Ltd., NFI, regarded the education and development of skilled operators very seriously and we have developed an education system, called the SD system (Skill Development system), to assure the careful education of the operators and the improvement of their skill in order to prevent human error events. Our education system in the Tokai works, is explained. (author)

  8. KEEFEKTIFAN BUDAYA LITERASI DI SD N 3 BANJAR JAWA UNTUK MENINGKATKAN MINAT BACA

    Directory of Open Access Journals (Sweden)

    I Putu Mas Dewantara

    2017-12-01

    Full Text Available Penelitian ini bertujuan untuk mengetahui sejauh mana keefektifan budaya literasi di SD N 3 Banjar Jawa untuk meningkatkan minat baca siswa. Metode atau teknik pengumpulan data yang digunakan dalam penelitian ini meliputi: wawancara, observasi, angket, dan kuisioner. Teknik analisis data yang digunakan dalam penelitian ini adalah model Miles dan Huberman, yaitu: reduksi, sajian data, dan penarikan simpulan. Dari hasil penelitian terjadi peningkatan minat baca siswa sebesar 27%. Program budaya literasi ini dikemas dengan kegiatan 15 menit membaca sebelum jam pelajaran, melaksanakan sabtu literasi, menata perpustakaan, dan menciptakan lingkungan yang kaya teks.

  9. Parity dependence in the optical potential of sd-shell nuclei

    International Nuclear Information System (INIS)

    Ferrero, J.L.; Ruiz, J.A.; Bilwes, B.; Bilwes, R.

    1989-01-01

    Elastic scattering between sd-shell nuclei differing by one, two, three and four nucleons has been measured. The oscillating pattern of the angular distributions, when it is observed, is attributed to the interference between direct elastic scattering and elastic transfer. Explicit DWBA treatment of the elastic transfer or parity dependent real potential analysis allow both a good reproduction of the data. The sign and the importance of the parity potential deduced by fitting the data are in good agreement with the predictions of microscopic calculations in the two centre shell-model

  10. Test of the fermion dynamical symmetry model microscopy in the sd shell

    International Nuclear Information System (INIS)

    Halse, P.

    1987-01-01

    The recently formulated fermion dynamical symmetry model treats low-lying collective levels as states classified in a pseudo-orbit pseudo-spin (k-i) basis having either k = 1 and zero i seniority, or i = (3/2) and zero k seniority. The validity of this suggestion, which has not previously been subjected to a microscopic examination, is determined for even-even nuclei in the sd shell, for which the model is phenomenologically successful, by comparing these states with the eigenfunctions of a realistic Hamiltonian. Most low-lying levels are almost orthogonal to the fermion dynamical symmetry model zero seniority subspaces

  11. Holter con memorias SD y sistema experto de evaluación cardíaca

    OpenAIRE

    Pfarher, Iván; Reula, Germán; Tovorosky, Pablo; Zanin, Miguel; Caballero, Raúl M.; Maggiolo, Gustavo Daniel

    2006-01-01

    Este desarrollo se enmarca dentro de las actividades de la cátedra de Técnicas Digitales de Ingeniería en Electrónica en UTN-FRP y tiene como objeto potenciar la capacidad de diseño de los alumnos. En este caso se ha desarrollado un sistema holter utilizando memorias SD comunes en el mercado de las cámaras fotográficas implementando además un sistema ordenador de control a partir del uso de un microcontrolador con el sistema de operación y de captura embebido correspondiente para la captura, ...

  12. Development of safety function assessment trees for pressurized heavy water reactor LP/SD operations

    International Nuclear Information System (INIS)

    Yang, Hui Chang; Chung, Chang Hyun; Kim, Ki Yong; Jee, Moon Hak; Sung, Chang Kyoung

    2003-01-01

    The objective of Configuration Risk Management Program(CRMP) is to maintain the safety level by assuring the defense-in-depth of nuclear power plant while the configurations are changed during plant operations, especially for the LP/SD. Such a safety purpose can be achieved by establishing the risk monitoring programs with both quantitative and qualitative features. Generally, the quantitative risk evaluation models, i.e., PRA models are used for the risk evaluation during full power operation, and the qualitative risk evaluation models such as safety function assessment trees are used. Through this study, safety function assessment trees were developed

  13. Modification of Iraqi Asphalt 40/50 Properties Using Saw Dust (SD and Natural Rubber Latex

    Directory of Open Access Journals (Sweden)

    Rusul l M. Darwesh

    2018-04-01

    Full Text Available The aim of this research is to enhance the fundamental properties for asphalt binder as those spec-ifications relate to performance of asphalt mixtures. In this paper studied the effect of add (2, 4 % SD in different sizes and (3, 5 and 7% Natural rubber latex to the straight asphalt 40/50 produced from Al-Dura refinery at 160C, it was added each additive separately and then added together to asphalt in same temperature, then tested physically and mechanically according to the American Society for Testing and Materials (ASTM, the result showed largely improvement.

  14. PENGEMBANGAN SSP TEMATIK INTEGRATIF UNTUK MEMBANGUN KARAKTER KEJUJURAN DAN KEPEDULIAN SISWA SD KELAS II

    Directory of Open Access Journals (Sweden)

    Sri Hariyati Qodriyah

    2015-07-01

    Full Text Available Penelitian ini bertujuan untuk menghasilkan perangkat pembelajaran berupa SSP Tematik yang dapat mengembangkan karakter siswa kelas 2 sekolah dasar, meliputi karakter kejujuran dan kepedulian. Penelitian ini merupakan penelitian dan pengembangan yang terdiri dari tujuh tahap, yaitu studi pendahuluan, perencanaan, mengembangkan produk awal, uji coba awal, revisi produk utama, uji coba lapangan, dan revisi terhadap produk operasional. SSP yang dikembangkan dievaluasi oleh seorang ahli materi dan media untuk mengetahui validitasnya. Subjek uji coba berjumlah 90 siswa terdiri dari 23 siswa SD Sonosewu, Kasihan, Bantul, DIY sebagai subjek uji coba terbatas dan 33 siswa untuk kelas control dan 34 siswa untuk kelas eksperimen SD 1 Kadipiro, Kasihan, Bantul, DIY. Hasil penelitian ini berupa SSP yang meliputi: silabus, RPP, LKS, dan lembar penilaian. Hasil evaluasi dari ahli materi dan ahli media untuk menguji tingkat kevalidan SSP menyatakan bahwa SSP yang dikembangkan adalah valid dan berkategori “baik”. Hasil uji coba menunjukkan bahwa SSP yang dikembangkan dinyatakan layak serta memenuhi kriteria praktis dan efektif dalam mengembangkan karakter siswa. Pembelajaran dengan SSP yang dikembangkan mampu mengembangkan karakter kejujuran dan kepedulian. Kata Kunci: SSP, karakter jujur dan peduli   DEVELOPING THEMATIC INTEGRATIVE SSP FOR BUILDING THE CHARACTERS OF HONESTY AND CARE GRADE II STUDENT OF ELEMENTARY SCHOOL Abstract This study aims to produce integrated learning sets in the form of thematic SSP that can develop the characters of honesty and care of grade II students of elementary school. This was a research and development study consisting of seven steps, i.e. preliminary study, planning, preliminary product development, preliminary tryout, main product revision, field tryout, revision of operational product, operational product revision, and revision of the final product. The developed SSP was evaluated by a science subject expert to assess

  15. Servikal nöral foraminal bölge ve uncinate çıkıntının embriolojik gelişimi ve anatomisinin klinikle ilişkilendirilmesi

    OpenAIRE

    BROHİ, Recep Ali

    2012-01-01

    Servikal bölge ile ilgili yapılan anatomik ve morfometrik çalışmaların büyük çoğunluğunda erişkin kadavra ve kemikleri kullanılmıştır. Servikal bölgenin ve bu bölge ile patolojilerde önemli rol oynayan uncinate proses ve servikal nöral foramen ile ilgili çalışmalar literatürde bulunsa da bu iki yapının embriolojik gelişimi yeterin...

  16. Türkiye’de Franchising Sisteminin Gelişimi ve Franchise Alan Girişimcilerin İş Memnuniyeti Belirleyicilerinin Analizi Üzerine Bir Araştırma

    OpenAIRE

    Nart, Sima

    2005-01-01

    Bu çalışmada, Türkiye’de Franchising sisteminin gelişimi ve bugünkü konumu incelendikten sonra Ulusal Franchising Derneği (UFRAD) üyesi Franchise-veren firmalardan Franchise-alan girişimcilerin iş memnuniyetlerini belirleyen etkenler üzerine bir anket çalışması yapılmıştır. Bulgular, franchise-alan işletmelerin memnuniyetlerinde sistem motivasyonu, işbirliği, güç dengesi, beklentiler ve franchise veren firmanın imajının belirleyici rol oynadığını göstermektedir. Araştırma sonuçları franchisev...

  17. Testing refined shell-model interactions in the sd shell: Coulomb excitation of Na26

    CERN Document Server

    Siebeck, B; Blazhev, A; Reiter, P; Altenkirch, R; Bauer, C; Butler, P A; De Witte, H; Elseviers, J; Gaffney, L P; Hess, H; Huyse, M; Kröll, T; Lutter, R; Pakarinen, J; Pietralla, N; Radeck, F; Scheck, M; Schneiders, D; Sotty, C; Van Duppen, P; Vermeulen, M; Voulot, D; Warr, N; Wenander, F

    2015-01-01

    Background: Shell-model calculations crucially depend on the residual interaction used to approximate the nucleon-nucleon interaction. Recent improvements to the empirical universal sd interaction (USD) describing nuclei within the sd shell yielded two new interactions—USDA and USDB—causing changes in the theoretical description of these nuclei. Purpose: Transition matrix elements between excited states provide an excellent probe to examine the underlying shell structure. These observables provide a stringent test for the newly derived interactions. The nucleus Na26 with 7 valence neutrons and 3 valence protons outside the doubly-magic 16O core is used as a test case. Method: A radioactive beam experiment with Na26 (T1/2=1,07s) was performed at the REX-ISOLDE facility (CERN) using Coulomb excitation at safe energies below the Coulomb barrier. Scattered particles were detected with an annular Si detector in coincidence with γ rays observed by the segmented MINIBALL array. Coulomb excitation cross sections...

  18. Anisotropic SD2 brane: accelerating cosmology and Kasner-like space-time from compactification

    Energy Technology Data Exchange (ETDEWEB)

    Nayek, Kuntal; Roy, Shibaji [Saha Institute of Nuclear Physics, Calcutta (India); Homi Bhabha National Institute, Mumbai (India)

    2017-07-15

    Starting from an anisotropic (in all directions including the time direction of the brane) non-SUSY D2 brane solution of type IIA string theory we construct an anisotropic space-like D2 brane (or SD2 brane, for short) solution by the standard trick of a double Wick rotation. This solution is characterized by five independent parameters. We show that compactification on six-dimensional hyperbolic space (H{sub 6}) of a time-dependent volume of this SD2 brane solution leads to accelerating cosmologies (for some time t ∝ t{sub 0}, with t{sub 0} some characteristic time) where both the expansions and the accelerations are different in three spatial directions of the resultant four-dimensional universe. On the other hand at early times (t << t{sub 0}) this four-dimensional space, in certain situations, leads to four-dimensional Kasner-like cosmology, with two additional scalars, namely, the dilaton and a volume scalar of H{sub 6}. Unlike in the standard four-dimensional Kasner cosmology here all three Kasner exponents could be positive definite, leading to expansions in all three directions. (orig.)

  19. A framework for classification and segmentation of branch retinal artery occlusion in SD-OCT

    Science.gov (United States)

    Guo, Jingyun; Shi, Fei; Zhu, Weifang; Chen, Haoyu; Chen, Xinjian

    2016-03-01

    Branch retinal artery occlusion (BRAO) is an ocular emergency which could lead to blindness. Quantitative analysis of BRAO region in the retina is very needed to assessment of the severity of retinal ischemia. In this paper, a fully automatic framework was proposed to classify and segment BRAO based on 3D spectral-domain optical coherence tomography (SD-OCT) images. To the best of our knowledge, this is the first automatic 3D BRAO segmentation framework. First, a support vector machine (SVM) based classifier is designed to differentiate BRAO into acute phase and chronic phase, and the two types are segmented separately. To segment BRAO in chronic phase, a threshold-based method is proposed based on the thickness of inner retina. While for segmenting BRAO in acute phase, a two-step segmentation is performed, which includes the bayesian posterior probability based initialization and the graph-search-graph-cut based segmentation. The proposed method was tested on SD-OCT images of 23 patients (12 of acute and 11 of chronic phase) using leave-one-out strategy. The overall classification accuracy of SVM classifier was 87.0%, and the TPVF and FPVF for acute phase were 91.1%, 5.5%; for chronic phase were 90.5%, 8.7%, respectively.

  20. Geology of the USW SD-9 drill hole, Yucca Mountain, Nevada

    International Nuclear Information System (INIS)

    Engstrom, D.A.; Rautman, C.A.

    1996-10-01

    Drill hole USW SD-9 is one of several holes drilled under Site Characterization Plan Study as part of the characterization program at Yucca Mountain, Nevada, which has been proposed as the potential location of a repository for high-level nuclear waste. The SD-9 drill hole is located in the northern part of the potential repository area. Quantitative and semiquantitative data are included in this report for cover recovery, rock-quality designation (RQD), lithophysal cavity abundance, and fracturing. These data are spatially variable, both within and among the major formational-level stratigraphic units. Nonwelded intervals in general exhibit higher recoveries and more intact (higher) RQD values than welded intervals. The most intact, highest-RQD materials encountered within the Topopah Spring belong to the lower 33.3 ft of the middle nonlithophysal zone. This report includes quantitative data for the framework material properties of porosity, bulk and particle density, and saturated hydraulic conductivity. Graphical analysis of variations in these laboratory hydrologic properties indicates first-order control of material properties by the degree of welding and the presence of zeolite minerals. Many major lithostratigraphic contacts are not well expressed in the material-property profiles; contacts of material-property units are related more to changes in the intensity of welding. Approximate in-situ saturation data of samples preserved immediately upon recovery from the hole are included in the data tabulation

    1. EFEKTIVITAS PENGEMBANGAN MEDIA PERMAINAN ULAR TANGGA SEBAGAI SARANA BELAJAR TEMATIK SD

      Directory of Open Access Journals (Sweden)

      Moch. Chabib

      2017-07-01

      Full Text Available Playing by learning is a way of learning that appropriate with the characteristics of elementary school children today. Which (1 Start of critical thinking. (2 Start emerging competition between friends. (3 Having a deep curiosity. (4 Love asked and (5 Likes groups. This is supported by the results of the field observations showed that when the class is still a lot of students were busy playing and tend to be passive, when the teacher was giving a lesson. Traditional game of snakes and ladders is familiar with elementary school children. Therefore we need a through study on how to take advantage of this game help the studen learning, so it is can solve the problem of declining motivation and involvement of the student in the classroom. Bermain sambil belajar merupakan sebuah pendekatan pembelajaran yang sangat sesuai dengan karakteristik belajar anak SD saat ini, yaitu (1 mulai berpikir kritis, (2 mulai muncul persaingan antar teman, (3 mempunyai rasa ingin tahu yang mendalam, (4 suka bertanya, dan (5 suka berkelompok. Hal ini didukung dengan hasil pengamatan di lapangan yang menunjukkan bahwa ketika dikelas masih banyak siswa yang asyik bermain dan cenderung pasif, padahal guru sedang memberikan penjelasan.Permainan ular tangga merupakan permainan tradisional yang sudah akrab dengan anak SD. Oleh karena itu, diperlukan sebuah kajian yang mendalam tentang bagaimana cara memanfaatkan permainan ini dalam pembelajaran sehingga dapat mengatasi masalah tentang menurunnya motivasi dan keaktifan siswa di kelas.

    2. Anisotropic SD2 brane: accelerating cosmology and Kasner-like space-time from compactification

      International Nuclear Information System (INIS)

      Nayek, Kuntal; Roy, Shibaji

      2017-01-01

      Starting from an anisotropic (in all directions including the time direction of the brane) non-SUSY D2 brane solution of type IIA string theory we construct an anisotropic space-like D2 brane (or SD2 brane, for short) solution by the standard trick of a double Wick rotation. This solution is characterized by five independent parameters. We show that compactification on six-dimensional hyperbolic space (H_6) of a time-dependent volume of this SD2 brane solution leads to accelerating cosmologies (for some time t ∝ t_0, with t_0 some characteristic time) where both the expansions and the accelerations are different in three spatial directions of the resultant four-dimensional universe. On the other hand at early times (t << t_0) this four-dimensional space, in certain situations, leads to four-dimensional Kasner-like cosmology, with two additional scalars, namely, the dilaton and a volume scalar of H_6. Unlike in the standard four-dimensional Kasner cosmology here all three Kasner exponents could be positive definite, leading to expansions in all three directions. (orig.)

    3. IMPLEMENTASI MODEL PEMBELAJARAN TWO STAY TWO STRAY DALAM PEMBELAJARAN BERBASIS KEMAMPUAN BERPIKIR KRITIS KELAS V SD

      Directory of Open Access Journals (Sweden)

      M. Yusuf Setia Wardana

      2017-04-01

      Full Text Available Benefits of mathematics are to equip students with the ability to think logically, analytical, systematically, critically, and creatively, as well as the ability to cooperate. Based on observations in elementary school, there are 40% of students have not reached KKM and students have lack of critical abilities to understand math problems, and they have low activity of the study. One of models that can be applied is Two Stay Two Stray. The study used True Experimental Design with Posttest-Only Control Design. The population in this study was all fifth grade students of SD Negeri Semarang Rejosari 03. Data of critical thinking skills of the students in average on test of critical thinking skills mastery was 3.31 ≥ 2.67, it can be said to have a complete description. The conclusion is a model of Two Stay Two Stray being effective for critical thinking skills and mathematics learning outcomes of fifth grade students in SD Negeri Rejosari 03 Semarang. Keywords: two stay two stray model, critical thinking ability.

    4. Mechanical Properties Variation of B500SD High Ductility Reinforcement Regarding its Corrosion Degree

      Directory of Open Access Journals (Sweden)

      Cobo, A.

      2011-12-01

      Full Text Available Corrosion effects on reinforcement become evident in the bar section reduction and in the variation of mechanical properties related to ductility. In this research work, 96 B500SD steel bars, previously subjected to different corrosion variables, have been tested. Results show that the elongation of the bars diminishes and the ratio between the maximum tensile stress and the elastic limit increases as the corrosion degree advances. These phenomena can be explained by studying the necking effect and the different steel composition through the manufacture process.

      Los efectos de la corrosión sobre las armaduras se manifiestan por la pérdida de sección y la variación de las propiedades mecánicas relacionadas con la ductilidad. En este trabajo se han ensayado a tracción 96 barras de acero B500SD que previamente se han sometido a niveles variables de corrosión. Los resultados muestran que los alargamientos de las barras disminuyen y el cociente entre la tensión máxima y el límite elástico aumenta conforme el nivel de corrosión avanza. A partir del estudio del efecto de entalla y de la distinta constitución metalográfica del acero a nivel de sección debido a su procedimiento de fabricación, se pueden explicar los fenómenos anteriores.

    5. Geology of the USW SD-9 drill hole, Yucca Mountain, Nevada

      Energy Technology Data Exchange (ETDEWEB)

      Engstrom, D.A. [Spectra Research Inst., Albuquerque, NM (United States); Rautman, C.A. [Sandia National Labs., Albuquerque, NM (United States)

      1996-10-01

      Drill hole USW SD-9 is one of several holes drilled under Site Characterization Plan Study as part of the characterization program at Yucca Mountain, Nevada, which has been proposed as the potential location of a repository for high-level nuclear waste. The SD-9 drill hole is located in the northern part of the potential repository area. Quantitative and semiquantitative data are included in this report for cover recovery, rock-quality designation (RQD), lithophysal cavity abundance, and fracturing. These data are spatially variable, both within and among the major formational-level stratigraphic units. Nonwelded intervals in general exhibit higher recoveries and more intact (higher) RQD values than welded intervals. The most intact, highest-RQD materials encountered within the Topopah Spring belong to the lower 33.3 ft of the middle nonlithophysal zone. This report includes quantitative data for the framework material properties of porosity, bulk and particle density, and saturated hydraulic conductivity. Graphical analysis of variations in these laboratory hydrologic properties indicates first-order control of material properties by the degree of welding and the presence of zeolite minerals. Many major lithostratigraphic contacts are not well expressed in the material-property profiles; contacts of material-property units are related more to changes in the intensity of welding. Approximate in-situ saturation data of samples preserved immediately upon recovery from the hole are included in the data tabulation.

    6. FY 2000 report on the results of the regional consortium R and D project - Regional consortium energy R and D. Final year report. Development of the measuring control technology supporting energy conservation in the manufacturing process of electronics (Design and trial manufacture of IMI); 2000 nendo chiiki consortium kenkyu kaihatsu jigyo - chiiki consortium energy kenkyu kaihatsu. Denshi kikirui seizo process no sho energy shien keisoku seigyo gijutsu no kaihatsu - IMI no sekkei to shisaku (saishu nendo) seika hokokusho

      Energy Technology Data Exchange (ETDEWEB)

      NONE

      2001-03-01

      As measures taken for energy conservation in the manufacturing plant of electronic devices/equipment such as IC, the development was proceeded with a chlorine gas radio sensing system and a liquid crystal driver IC probe, according to the survey results that it is possible to control energy consumption in air conditioning by completely furnishing poisonous gas monitor in clean room and conserve energy related to the manufacture of IC and LSI tester by using Si for IC probe cards. The following four were carried out: 1) development/trial manufacture of chlorine sensing system; 2) development/trial manufacture of LCD (liquid crystal driver) IC probe; 3) support of trial manufacture of key element technology; 4) comprehensive investigational study of IMI (Intelligent Micro-Instrument). In FY 2000, study was focused on 1) and 2). In 1), a planar type micro-structure sensor was developed, and the trial-manufactured system brought favorable results in sensitivity, response speed and reproductivity. (NEDO)

    7. Purification, characterization and anti-aging capacity of mycelia zinc polysaccharide by Lentinus edodes SD-08.

      Science.gov (United States)

      Wang, Liqin; Wang, Cuiqin; Gao, Xia; Xu, Nuo; Lin, Lin; Zhao, Huajie; Jia, Shouhua; Jia, Le

      2015-04-09

      In the modern society, aging had been a major problem. People may rely on many medicines to delay it. However, lots of medicines were chemosynthetic, and they would do a bad side-effect on human body. Microbial sources could be used as a potential means of producing natural antioxidants. Lentinus edodes, commercial obtained in daily life, had recently become more attractive in physiological research. Zinc was now considered as a major element in assuring the correct functioning of an organism and essential for maintaining coordination of the major homeostatic networks. To investigate the bioconversion of zinc and the physiological effects of their complex (MZPS), the present studies were processed. Mycelia polysaccharides (MPS) and mycelia zinc polysaccharides (MZPS) of Lentinus edodes SD-08 were extracted by hot water leaching and purified by DEAE-52 cellulose anion-exchange column chromatography separately. The zinc content was determined by flame atomic absorption spectrometry. The evaluation of monosaccharide compositions and proportions used gas chromatogram. The analysis of molecular weight used HPGPC chromatogram. The typical structure of polysaccharide was evaluated by IR spectrum. The antioxidant activities in vitro measured through reducing power, the scavenging effects on hydroxyl radical and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. The anti-aging activities in vivo measured through the total antioxidant capacity (T-AOC), GSH peroxide (GSH-Px), superoxide dismutase (SOD) and the contents of malondialdehyde (MDA). MPS and MZPS of Lentinus edodes SD-08 were extracted and purified by DEAE-52 cellulose anion-exchange column chromatography separately, and four fractions (MPS-1, MPS-2, MZPS-1 and MZPS-2) were obtained. In addition, MPS composing of rhamnose, arabinose and mannose (molar proportion = 1.75:1.00:3.02) and MZPS containing rhamnose, arabinose, mannose and glucose (molar proportion = 7.19:2.26:1.00:8.39) were investigated by gas chromatography

    8. PENGEMBANGAN SSP TEMATIK-INTEGRATIF UNTUK MEMBANGUN KARAKTER DISIPLIN DAN KREATIF SISWA KELAS I SD

      Directory of Open Access Journals (Sweden)

      Wawan Wahyu Setyawan

      2015-01-01

      DEVELOPING THEMATIC-INTEGRATED SSP FOR BUILDING THE CHARACTERS OF DISCIPLINE AND CREATIVE OF GRADE I STUDENT ELEMENTARY SCHOOL ABSTRACT This study aims to produce integrated learning sets in the form of thematic SSP that can develop the characters of discipline and creative of grade I students of elementary school.This was a research and development study consisting of seven steps, namely: preliminary study and data collection, planning, product draft development, preliminary field tryout, revision of the tryout result, field tryout, product finalization based the field tryout result, field implementation testing, final product finalization, and dissemination. The developed SSP was evaluated by a science subject expert to assess the validity. The tryout subjects comprised 82 students consisting of 26 students of SD Baran, Pundong, Bantul, DIY in the small-scale tryout, 25 students in the control class of SD Manding Tengah, Bantul, DIY and 31 students in the experimental class of SD 1 Tulung, Bantul, DIY. The results of this study are in the form of SSP consisting of: a syllabus, lesson plans, course sheets, student worksheets, and evaluation sheets. The results of the evaluation show that the developed syllabus is good score of 47. The developed lesson plans score of 67, student course sheets score of 65, student worksheets score of 47, and assessment instruments, are very good , while the developed learning media are good score of 66. The results of the tryout show that the developed SSP otherwise meet the criteria for the practical views of teacher assessment score of 281 and a score of 730 student responses. In field trials the results obtained for the control class average pretest score of 70.8 and an average posttest score of 80.8. While the experimental class scored an average of 74.1 pretest and posttest score of 90.9. Improved control class scores of 10 and an increase of 16.8 experimental class. Teaching using developed SSP is capable of developing

    9. High spin structure of {sup 35}Cl and the sd-fp shell gap

      Energy Technology Data Exchange (ETDEWEB)

      Kshetri, Ritesh [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Saha Sarkar, M. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India)]. E-mail: maitrayee.sahasarkar@saha.ac.in; Ray, Indrani [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Banerjee, P. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Sarkar, S. [Department of Physics, Bengal Engineering and Science University, Shibpur, Howrah 711103 (India); Raut, Rajarshi [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Goswami, A. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Chatterjee, J.M. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Chattopadhyay, S. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Datta Pramanik, U. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Mukherjee, A. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Dey, C.C. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Bhattacharya, S. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Dasmahapatra, B. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Bhowal, Samit [Department of Physics, Surendranath Evening College, Kolkata 700009 (India); Gangopadhyay, G. [University of Calcutta, 92, Acharya Prafulla Chandra Road, Kolkata 700009 (India); Datta, P. [Anandamohan College, 102/1, Raja Rammohan Sarani, Kolkata 700009 (India); Jain, H.C. [Tata Institute of Fundamental Research, Mumbai 400005 (India); Bhowmik, R.K. [Inter-University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi 110067 (India); Muralithar, S.; Singh, R.P.; Kumar, R. [Inter-University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi 110067 (India)

      2007-01-15

      The high spin states of {sup 35}Cl have been studied by in-beam {gamma}-spectroscopy following the fusion-evaporation reaction {sup 12}C({sup 28}Si,{alpha}p){sup 35}Cl at E{sub lab}=70 and 88 MeV, using the Indian National Gamma (Clover) Array (INGA). Lifetimes of six new excited states have been estimated for the first time. To understand the underlying structure of the levels and transition mechanisms, experimental results have been compared with those from the large basis cross-shell shell model calculations. Involvement of orbitals from fp shell and squeezing of the sd-fp shell gap seem to be essential for reliable reproduction of high spin states.

    10. High spin structure of 35Cl and the sd-fp shell gap

      International Nuclear Information System (INIS)

      Kshetri, Ritesh; Saha Sarkar, M.; Ray, Indrani; Banerjee, P.; Sarkar, S.; Raut, Rajarshi; Goswami, A.; Chatterjee, J.M.; Chattopadhyay, S.; Datta Pramanik, U.; Mukherjee, A.; Dey, C.C.; Bhattacharya, S.; Dasmahapatra, B.; Bhowal, Samit; Gangopadhyay, G.; Datta, P.; Jain, H.C.; Bhowmik, R.K.; Muralithar, S.; Singh, R.P.; Kumar, R.

      2007-01-01

      The high spin states of 35 Cl have been studied by in-beam γ-spectroscopy following the fusion-evaporation reaction 12 C( 28 Si,αp) 35 Cl at E lab =70 and 88 MeV, using the Indian National Gamma (Clover) Array (INGA). Lifetimes of six new excited states have been estimated for the first time. To understand the underlying structure of the levels and transition mechanisms, experimental results have been compared with those from the large basis cross-shell shell model calculations. Involvement of orbitals from fp shell and squeezing of the sd-fp shell gap seem to be essential for reliable reproduction of high spin states

    11. KEEFEKTIFAN MULTIMEDIA BERBASIS KOMPUTER UNTUK PEMBELAJARAN ILMU PENGETAHUAN SOSIAL KELAS IV SD PERCOBAAN II DEPOK SLEMAN

      Directory of Open Access Journals (Sweden)

      Sri Budyartati

      2016-11-01

      Full Text Available This research aims at: (1 identifying the effecteiveness of multi media-based learning on Social Science; (2 describing the attractiveness of multi media-based learning on Social Science; which is carried out at SD Percobaan II Caturtunggal Depok Sleman Yogyakarta, term 2007/2008. The research design is pretest-posttest control group design. The data are drwan through tests which are analized quantitatively; and questionaire to measure the attractiveness of multimedia-based learning model, which will be analized qualitatavely. The treatment is carried out out by using storyboard, which is approved by experts of multimedia and teaching method. The result of the analysis shows that multi media-based learning model significantly influence the students’ achievement in Social Science. While the attractivemess of multi media-based learning relatively high, which is shown by 4.2 of average (in 1-5 scale measure.

    12. Intercomparison of natural radionuclide measurements in marine sediment sample SD-N-1/2

      International Nuclear Information System (INIS)

      1985-06-01

      This intercomparison exercise was organized with the aim of providing to the participating laboratories a possibility of testing the performance of their analytical methods and to acquire basic data for establishing reference values for a number of natural radionuclides in the sediment material SD-N-1/2 from the North Sea floor. In tables are presented results expressed in mBq.g -1 on potassium, uranium isotopes, thorium-232 with the respective decay products, thorium-230, radium-226 and lead-210. Altogether 98 laboratories from 42 Member States joined this intercomparison. The results show generally good agreement, but more analytical work is needed to improve the present status of the lead-210 certification. Gamma and alpha spectroscopy were the most frequently used as the analytical techniques

    13. Source identification in acoustics and structural mechanics using Sierra/SD.

      Energy Technology Data Exchange (ETDEWEB)

      Walsh, Timothy Francis; Aquino, Wilkins [Duke University Durham, NC; Ross, Michael

      2013-03-01

      In this report we derive both time and frequency-domain methods for inverse identification of sources in elastodynamics and acoustics. The inverse/design problem is cast in a PDE-constrained optimization framework with efficient computation of gradients using the adjoint method. The implementation of source inversion in Sierra/SD is described, and results from both time and frequency domain source inversion are compared to actual experimental data for a weapon store used in captive carry on a military aircraft. The inverse methodology is advantageous in that it provides a method for creating ground based acoustic and vibration tests that can reduce the actual number of flight tests, and thus, saving costs and time for the program.

    14. Charge radii of magnesium isotopes by laser spectroscopy a structural study over the $sd$ shell

      CERN Multimedia

      Schug, M; Krieger, A R

      We propose to study the evolution of nuclear sizes and shapes over the magnesium chain by measuring the root-mean-square charge radii of $^{21 - 32}$Mg, essentially covering the entire $\\textit{sd}$ shell. Our goal is to detect the structural changes, which in the neutron-deficient isotopes may originate from clustering, in a way similar to neon, and on the neutron-rich side would characterize the transition to the "island of inversion". We will combine, for the first time, the sensitive $\\beta$-detection technique with traditional fluorescence spectroscopy for isotope-shift measurements and in such a way gain access to the exotic species near the ${N}$ = 8 and ${N}$ = 20 shell closures.

    15. Simulation and Optimization of One Live Pig Low-Carbon Industry Chain Using SD-RCCM

      Directory of Open Access Journals (Sweden)

      Jiuping Xu

      2013-01-01

      Full Text Available The destruction of the natural environment has been drawing more and more attention. Developing low-carbon industry chains is an effective solution to the conflict between rapid economic growth and high CO2 emissions. Summarizing various traditional and new industry chain sustainable development, live pig industry was chosen as a typical industry chain to study low-carbon development using a system dynamics and random chance-constrained model (SD-RCCM. Leshan, a world natural and cultural heritage area in China, was selected as a typical city to analyze the low-carbon pig industry. Three different programs based on distribution ratios were selected to study this industry. The results showed that program 1, which considers both environmental and economic benefits, realizes sustainable development. In order to extend the pig industry chain and fully utilize pig ordure and other waste, introducing a Clean Development Mechanism (CDM and household biogas exploitation program is recommended.

    16. ECOLITERACY SISWA SD DALAM KEGIATAN PENGELOLAAN SAMPAH MELALUI GROUP INVESTIGATION BERBASIS OUTDOOR STUDY

      Directory of Open Access Journals (Sweden)

      Fanny Karlina

      2017-07-01

      Full Text Available The aim of this research is to improve the student’s ecoliteracy in waste managing activities on social studies trough group investigation based outdoor study. This research is Classroom Action Research toward fourth graders have been held on two cycles. The conclusion of this research is student’s ecoliteracy cognitive aspect increases is 20%, application aspect increases is 49,6%, and attitude aspect increases is 19,4% after the two cycle action with group investigation based outdoor study. Penelitian ini bertujuan mendeskripsikan peningkatan ecoliteracy siswa dalam kegiatan pengelolaan sampah dalam pembelajaran IPS melalui group investigation berbasis outdoor study. Penelitian ini menerapkan jenis Penelitian Tindakan Kelas (PTK terhadap siswa kelas IV SD yang dilaksanakan dalam dua siklus. Hasil penelitian menyimpulkan adanya peningkatan ecoliteracy siswa dari aspek pengetahuan sebesar 20%, aspek aplikasi sebesar 49,6%, dan aspek sikap sebesar 19,4% setelah mengikuti dua siklus pembelajaran dengan group investigation berbasis outdoor study.

    17. An automated approach for early detection of diabetic retinopathy using SD-OCT images.

      Science.gov (United States)

      ElTanboly, Ahmed H; Palacio, Agustina; Shalaby, Ahmed M; Switala, Andrew E; Helmy, Omar; Schaal, Shlomit; El-Baz, Ayman

      2018-01-01

        This study was to demonstrate the feasibility of an automatic approach for early detection of diabetic retinopathy (DR) from SD-OCT images. These scans were prospectively collected from 200 subjects through the fovea then were automatically segmented, into 12 layers. Each layer was characterized by its thickness, tortuosity, and normalized reflectivity. 26 diabetic patients, without DR changes visible by funduscopic examination, were matched with 26 controls, according to age and sex, for purposes of statistical analysis using mixed effects ANOVA. The INL was narrower in diabetes (p = 0.14), while the NFL (p = 0.04) and IZ (p = 0.34) were thicker. Tortuosity of layers NFL through the OPL was greater in diabetes (all p diabetes. In turn, carries the promise to a reliable non-invasive diagnostic tool for early detection of DR.

    18. Penelitian tentang ukuran acuan sepatu pelajar wanita indonesia tingkat SD, SLTP dan SLTA

      Directory of Open Access Journals (Sweden)

      Sri Bandi

      1995-06-01

      Full Text Available The study was subjected to 500 Indonesia School girls from North Sumatra Province (Medan, West Java Province (Bandung, Central – Java Province (Semarang, East-Java Province (Surabaya and DKI Jaya. 100 samples of foot sizes which represented foot sizes of SD, SLTP and SLTA School girls werw taken from each province. By analyzing the data of foot sizes of the school girls, a suggestion on design of shoe lasts seritable with the shape and type of foot, fits and conform the requirements to be used as lost in shoe manufacturing could be proposed. The results of data analyse shown that : 1. The length of soles ranged from 30-35, 5 PS, the mean of which was 33 PS. 2. Instep girth ranged withim E, F, G, I.3. The foot sizes scattered between (4-17 years of age at (32-35 PS.

    19. Spectral Analysis of the sdO Standard Star Feige 34

      Science.gov (United States)

      Latour, M.; Chayer, P.; Green, E. M.; Fontaine, G.

      2017-03-01

      We present our current work on the spectral analysis of the hot sdO star Feige 34. We combine high S/N optical spectra and fully-blanketed non-LTE model atmospheres to derive its fundamental parameters (Teff, log g) and helium abundance. Our best fits indicate Teff = 63 000 K, log g = 6.0 and log N(He)/N(H) = -1.8. We also use available ultraviolet spectra (IUE and FUSE) to measure metal abundances. We find the star to be enriched in iron and nickel by a factor of ten with respect to the solar values, while lighter elements have subsolar abundances. The FUSE spectrum suggests that the spectral lines could be broadened by rotation.

    20. Sustainable development business case report : renewable electricity generation : SD business case

      International Nuclear Information System (INIS)

      2005-11-01

      This investment report is the first in a series that will be released by Sustainable Development Technology Canada as part of the SD Business Case. It focuses primarily on generating electricity from renewable energy sources and examines 4 primary technology groups or sub-sectors including wind generated electricity; solar PV generated electricity; stationary fuel cell generated electricity; and electricity generated from biological sources. Each sub-sector has been assessed in terms of its market dynamics, technology makeup and conditions, sustainability impacts, and investment risk. A selection of the leading technologies in each technology area are brought forward and rated in terms of their respective investment potential. The report first presents an overview of the SD business case plan. It defines the primary audience of the report, lists the sectors and investment categories to be assessed by the business case and provides some background information on Sustainable Development Technology Canada. The report presents the framework for data collection and analysis and an executive summary of the complete report. It then presents the results of the market assessment report for each of the 4 sectors. This includes demand, infrastructure renewal, environmental commitments, renewable energy value proposition, and future market potential. The section covering the technology assessment report discusses the various technologies and ranks them. The sustainability assessment report section provides an economic, environmental and societal assessment of each sub-sector. Risk assessment is conducted in terms of technology and non-technology related risk. Last, the report presents conclusions and investment priorities. 11 tabs., 7 figs

    1. PENERAPAN SUPERVISI KUNJUNGAN KELAS UNTUK MENINGKATKAN KINERJA GURU SD NEGERI 2 KALIMANGGIS KECAMATAN KALORAN, TEMANGGUNG

      Directory of Open Access Journals (Sweden)

      Suprih Danurwati

      2015-12-01

      Full Text Available Suprih Danurwati, 942013161. Implementation of supervision class visiting to increase teacher’s performance of SD Negeri 2 Kalimanggis District of Kaloran. Thesis. The graduatiton Program Master of Management Education Satya Wacana Christian University Salatiga. Supervisor Prof. Dr. Slameto, M.Pd. This study is to determine that through the implementation of supervision class visiting can improve the performance of teachers in the learning management. The subjects of this study are teachers in SD Negeri 2 Kalimanggis, Kaloran, Temanggung.  The procedure used in this study consists of a series of three main activities undertaken in a repeating cycle, including (a plan, (b action by observation, and (c reflection. research approach using action research methods, while the method of data collection using the study documentation, observations, questionnaires, and interviews. The results showed an increasing in the ability of teachers to prepare lesson plans and manage the learning of the first act, second, until the third act. The inference that supervision class visiting that can improve the performance of teachers in the learning management. Suggestions given to teachers, is taking  advantage of supervision activities as a source of information to improve the competence and performance, for principals use the results of this study as a reference in conducting research, while for school superintendent will use the results of this study as one of the references in activity guidance to the heads of schools and teachers to improve their performance.

    2. Culture Optimization and Amino Acid Composition of Cr-Enriched Mycelia of Pleurotus cornucopiae SD-01

      Directory of Open Access Journals (Sweden)

      Fan-Yun Meng

      2010-01-01

      Full Text Available Chromium(III is an essential trace element for humans and animals. Pleutorus cornucopiae SD-01 is a nutritional and functional mushroom containing many kinds of bioactive ingredients. The aims of this work are to optimize the conditions of P. cornucopiae SD-01 cultivation with Cr enrichment in submerged culture by determining the dry cell mass, Cr content in mycelia and the rate of Cr enrichment, and to analyze the amino acid composition of Cr-enriched mycelia. The optimal medium contained (in g/L: potato 200, sucrose 25, yeast extract 4, KH2PO4 1 and MgSO4·7H2O 1. The optimum parameters of liquid culture were temperature 25 °C, cultivation time 6 days, the volume of the medium 100 mL, rotation speed 160 rpm and initial pH=6.5. Under the optimized conditions, the values of the dry cell mass, Cr content in mycelia and the rate of Cr enrichment were (6.63±0.35 g/L, (3670±211 μg/g and (12.15±1.01 % respectively, which were by (23.23±1.22, (18.19±1.06 and (45.68±2.67 % respectively, higher than those in the control. Chromium(III in Cr-enriched mycelia was mainly combined with protein and polysaccharide. The contents of total amino acids and essential amino acids in Cr-enriched mycelia were increased by (31.25±0.58 and (44.26±0.76 %, respectively.

    3. INTERVENSI ERGONOMI DALAM PEMBELAJARAN SAINS MENGURANGI KELUHAN MUSKULOSKELETAL SISWA SD 1 SANGSIT KECAMATAN SAWAN KABUPATEN BULELENG

      Directory of Open Access Journals (Sweden)

      Nyoman Wijana

      2014-09-01

      Full Text Available Tujuan penelitian ini adalah untuk mengetahui peranan intervensi ergonomi dalam pembelajaran sains untuk menurunkan keluhan muskuloskeletal siswa SD. Jenis penelitian ini termasuk jenis penelitian quasi eksperimental dengan rancangan randomized pre-test and post-test control group design. Pada kelompok kontrol pembelajarannya dengan cara konvensional (tanpa intervensi ergonomi dan kelompok eksperimen dengan intervensi ergonomi. Intervensi ergonomi dalam pembelajaran sains mengacu pada pendekatan ergonomi (PE yakni gabungan antara SHIP dan TTG. Implementasi dari hal ini adalah melakukan perbaikan dan atau penataan terhadap instrumental input, environmental input dan porcess, sedangkan untuk di kelompok kontrol tidak dilakukan intervensi ergonomi, di mana kondisi instrumental input, environmental input dan process berlangsung secara konvensional. Pengambilan sampel dilakukan secara random. Analisis data dilakukan dengan menggunakan uji Mann-Whitney dengan taraf signifikansi 5 %. Simpulan dari hasil penelitian ini adalah (1 intervensi ergonomi dapat menurunkan keluhan muskuloskeletal siswa SD  (p < 0,05; (2 Hasil pengukuran dengan nordic body map pada kelompok kontrol terjadi keluhan pada otot pinggang (86,1%, otot pantat (86,1%, otot punggung (84,8%, otot lengan atas kiri (78,8%, otot lengan atas kanan (67,9%, otot siku kanan (78,2%, otot siku kiri (74,6%, paha kanan (76,9%, paha kiri (75,7%, otot betis kanan  (66,1%, otot betis kiri (64,2%, otot pergelangan kaki kanan (67,3%, dan otot pergelangan kaki kiri (65,5%. Dengan demikian dapat disarankan bahwa intervensi ergonomi dalam pembelajaran dengan menggunakan PE sebaiknya diterapkan dalam pembelajaran sains di SD karena telah terbukti dapat menurunkan keluhan muskuloskeletal.[MEDICINA 2009;40:11-20].  

    4. Peningkatan Pengetahuan Dan Keterampilan Guru SD Muhammadiyah 4 Batu Dalam Mengelola Pembelajaran ABK melalui Lesson Study

      Directory of Open Access Journals (Sweden)

      Endang Poerwanti

      2015-08-01

      Full Text Available Anak-anak dengan kebutuhan khusus (ABK yang dikenal sebagai anak-anak cacat, atau anak-anak yang luar biasa, anak-anak yaitu yang menyimpang secara signifikan dari kriteria normal, baik dari aspek fisik, psikologis, emosional dan sosial. Mulai tahun 2001, pemerintah mulai program pendidikan inklusif, pendidikan inklusif adalah untuk memasukkan anak-anak dengan kebutuhan khusus belajar bersama dengan anak normal di kelas dan sekolah reguler. Masalahnya, guru di sekolah reguler tidak berpendidikan dan dipersiapkan khusus untuk mengelola proses belajar mengajar untuk ABK. Masalah juga dialami oleh SD Muhammadiyah 4 Batu, untuk membantu memecahkan masalah tim FKIP menerapkan aktivitas Lesson Study untuk meningkatkan pengetahuan guru dan keterampilan dalam mengelola ABK pembelajaran individual Lesson study yang dilakukan dalam tiga siklus yang dikemas dalam tiga model pembelajaran; ABK belajar sendiri di kelas khusus, pengajaran dan pembelajaran di kelas reguler dan pengajaran dan pembelajaran ABK di kelas reguler dengan bantuan GPK. Setiap siklus terdiri dari beberapa kegiatan. Studi pelajaran terdiri dari empat kegiatan yang disingkat PDCA; P (rencana atau perencanaan, D (lakukan adalah pelaksanaan pembelajaran oleh seorang guru sebagai model dan diamati oleh guru lainnya, C (cek merupakan cerminan dari perbaikan lebih lanjut proses pembelajaran, dan A (tindak adalah tindak lanjut.  Dari tiga tahapan pelaksanaan proses belajar mengajar ABK dapat memberikan manfaat bagi para guru untuk meningkatkan pemahaman dan keterampilan untuk mengelola pembelajaran untuk ABK. Melalui Lesson Study diharapkan ABK mendapatkan layanan yang tepat dan belajar yang optimal. Beberapa temuan dampak pada perilaku siswa di kelas adalah bahwa siswa dapat menerima keberadaan ABK di. Meskipun keterbatasan kelas fasilitas guru mendapatkan pengalaman berharga yang terkait dengan pengembangan pembelajaran melalui forum ABK Lesson Study. Jadi kebutuhan untuk pelaksanaan tindak

    5. Validated automatic segmentation of AMD pathology including drusen and geographic atrophy in SD-OCT images.

      Science.gov (United States)

      Chiu, Stephanie J; Izatt, Joseph A; O'Connell, Rachelle V; Winter, Katrina P; Toth, Cynthia A; Farsiu, Sina

      2012-01-05

      To automatically segment retinal spectral domain optical coherence tomography (SD-OCT) images of eyes with age-related macular degeneration (AMD) and various levels of image quality to advance the study of retinal pigment epithelium (RPE)+drusen complex (RPEDC) volume changes indicative of AMD progression. A general segmentation framework based on graph theory and dynamic programming was used to segment three retinal boundaries in SD-OCT images of eyes with drusen and geographic atrophy (GA). A validation study for eyes with nonneovascular AMD was conducted, forming subgroups based on scan quality and presence of GA. To test for accuracy, the layer thickness results from two certified graders were compared against automatic segmentation results for 220 B-scans across 20 patients. For reproducibility, automatic layer volumes were compared that were generated from 0° versus 90° scans in five volumes with drusen. The mean differences in the measured thicknesses of the total retina and RPEDC layers were 4.2 ± 2.8 and 3.2 ± 2.6 μm for automatic versus manual segmentation. When the 0° and 90° datasets were compared, the mean differences in the calculated total retina and RPEDC volumes were 0.28% ± 0.28% and 1.60% ± 1.57%, respectively. The average segmentation time per image was 1.7 seconds automatically versus 3.5 minutes manually. The automatic algorithm accurately and reproducibly segmented three retinal boundaries in images containing drusen and GA. This automatic approach can reduce time and labor costs and yield objective measurements that potentially reveal quantitative RPE changes in longitudinal clinical AMD studies. (ClinicalTrials.gov number, NCT00734487.).

    6. Lactogenic Activity of an Enzymatic Hydrolysate from Octopus vulgaris and Carica papaya in SD Rats.

      Science.gov (United States)

      Cai, Bingna; Chen, Hua; Sun, Han; Sun, Huili; Wan, Peng; Chen, Deke; Pan, Jianyu

      2015-11-01

      The traditional Chinese medicine theory believes that octopus papaya soup can stimulate milk production in lactating women. The objective of this study was to determine whether dietary supplementation with an enzymatic hydrolysate of Octopus vulgaris and Carica papaya (EHOC) could increase milk production and nutritional indexes in Sprague Dawley (SD) rats. Female SD rats (n = 24) were fed a control diet (n = 8), EHOC-supplemented diet, or a positive control diet (Shengruzhi) from day 10 of pregnancy to day 10 of lactation. Maternal serum, mammary gland (day 10 of lactation), milk, and pup weight (daily) were collected for analysis. Results showed that the EHOC diet obviously elevated daily milk yield and pup weight compared to the control group (P < .05). The EHOC diet was found to increase the concentration of prolactin (PRL), progesterone (P), estradiol (E2), and growth hormone (GH) significantly in the circulation and mammary gland. Mammary glands of EHOC-treated dams showed clear lobuloalveolar development and proliferation of myoepithelial cells, but no striking variations were observed among the groups. Furthermore, the nutrition content and immune globulin concentration in the milk of EHOC-supplemented dams were higher than those of the control group, especially the cholesterol, glucose, and IgG were higher by 44.98% (P < .001), 42.76% (P < .01), and 42.23% (P < .01), respectively. In conclusion, this article demonstrates that EHOC administration has beneficial effects on milk production in the dams and on performance of the dam and pup. These results indicate that EHOC could be explored as a potentially lactogenic nutriment for lactating women.

    7. MODEL PEMBELAJARAN PENJAS MELALUI PERMAINAN UNTUK PEMBENTUKAN KARAKTER KERJA SAMA, TANGGUNG JAWAB DAN KEJUJURAN SISWA SD

      Directory of Open Access Journals (Sweden)

      Rubiyatno Rubiyatno

      2013-09-01

      Abstract This study aims at delivering game models for especially top grade elementary school students to build character, cooperation, responsibility and honesty that are ready to use. The teachers are expected to use this game model as one of integrated character value instructional forms that is appropriate and effective through enjoyable playing activities.This educational research and development (R & D was conducted by adapting R & D steps consisting of: (1 collecting information and information analysis, (2 developing initial product, (3 expert validation and revision, (4 preliminary field test and revision, (5 main field test and revision, and (6 making the final product. The preliminary field test was conducted to 14 students year 5 of SD.N.Pantaran Kulon Progo and the main field test was conducted to 40 students Class 4 and 5 of SD.N.2 Kalipetir Pengasih Kulon Progo. Data collecting instrument used were: (1 interview guide, (2 rating scale, (3 observation guide for games observation, (4 observation guide for games effectiveness, and (5 observation guide for perpetrator teachers. The data were analyzed using quantitative descriptive analysis and qualitative descriptive analysis.The result of this study is in the form of a game guidance book of integrated character building for corporation, responsibility, and honesty in the form of physical activities for upper grade elementary school students, consisting of six games: (1 blast fishing game, (2 ball war game, (3 shoot the ball to the hula hoop game, (4 my goal and basket game, (5 volley throw and catch, and (6 touching ball to the body game. As a conclusion, the game models are very good and effective to transfer character value, corporation, responsibility, and honesty Keywords: model of learning, character and elemantary students.

    8. [Choroidal thickness assessment with SD-OCT in high myopia with dome-shaped macula].

      Science.gov (United States)

      Chebil, A; Ben Achour, B; Chaker, N; Jedidi, L; Mghaieth, F; El Matri, L

      2014-03-01

      To measure macular choroidal thickness (CT) using spectral-domain optical coherence tomography (SD-OCT) in highly myopic eyes with dome-shaped macula (DSM), and to investigate whether the choroid is thicker in these eyes compared to highly myopic eyes without MB. A cross-sectional study of 200 eyes was performed between January 2010 and June 2012. Twenty-four highly myopic eyes (12%) had a dome-shaped macula. All patients underwent a complete ophthalmological examination, SD-OCT (TOPCON 2000), and B-scan ultrasonography. OCT scans were analyzed in 7 sections, and subfoveal CT was measured manually between the Bruch's membrane and the internal aspect of the sclera. The 20 eyes with isolated dome-shaped macular were paired by age and axial length (AL) with 20 eyes without macular involvement. In the subgroup with isolated MB, the mean subfoveal CT was 101.86 μm (± 21.35 μm). A statistically significant negative correlation was found between CT and AL (r=-0.623, P=0.0001). The regression equation demonstrated a decrease of 8.3 μm per mm of AL. In the subgroup without MB, matched with the subgroup with MB by age (P=0.591), and AL (P=0.815), the mean subfoveal CT was 89.54 μm (± 20.12 μm). The comparison between the two subgroups found a statistically significant difference in subfoveal CT (Pmacula compared to highly myopic eyes without dome-shaped macula. These findings suggest that abnormalities of the choroid may play a role in the pathogenesis of dome-shaped macula. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

    9. Effect of fermented milk containing Lactobacillus rhamnosus SD11 on oral microbiota of healthy volunteers: A randomized clinical trial.

      Science.gov (United States)

      Rungsri, P; Akkarachaneeyakorn, N; Wongsuwanlert, M; Piwat, S; Nantarakchaikul, P; Teanpaisan, R

      2017-10-01

      The aims of this study were to evaluate whether short-term consumption of fermented milk containing Lactobacillus rhamnosus SD11 affected levels of oral microbiota in vivo and whether L. rhamnosus SD11 could colonize in the human mouth. We also monitored for potential side effects of the probiotic. The applicability of using L. rhamnosus SD11 compared with Lactobacillus bulgaricus as a starter culture for fermented milk was evaluated. After informed consent, 43 healthy young adults were recruited and randomly assigned to either the probiotic or control group and received fermented milk containing L. rhamnosus SD11 or L. bulgaricus, respectively, once daily for 4 wk. The numbers of mutans streptococci, lactobacilli, and total bacteria in saliva were counted at baseline and then after 4 and 8 wk. An oral examination was performed at baseline and after 8 wk. The persistence of L. rhamnosus SD11 was investigated by DNA fingerprinting using arbitrary primer-PCR. Results demonstrated that statistically significant reductions in mutans streptococci and total bacteria were observed in the probiotic group compared with the control group, and the number of lactobacilli was significantly increased in both groups after receiving fermented milks. Lactobacillus rhamnosus SD11 could be detected (in >80% of subjects) up to 4 wk following cessation of dosing among subjects in the probiotic group. No side effects were reported. Thus, L. rhamnosus SD11 could be used as a starter culture for fermented milk. Daily consumption of L. rhamnosus SD11-containing fermented milk for 4 wk may have beneficial effects on oral health by reducing salivary levels of mutans streptococci. The probiotic was apparently able to colonize the oral cavity for a longer time than previously reported. However, the potential benefits of probiotic L. rhamnosus SD11 on oral health require further evaluation with a larger group of volunteers in a longer-term study. Copyright © 2017 American Dairy Science

    10. EFEKTIVITAS PROJECT BASED LEARNING TERHADAP KETERAMPILAN MENULIS BAHAN AJAR IPA CALON GURU SD

      Directory of Open Access Journals (Sweden)

      - Susilawati

      2018-01-01

      Full Text Available Abstract:. The purpose of this research is to analyze the effectiveness of Project Based Learning (PjBL of writing skills on Science teaching materials to elementary school teachers candidates.This research used experimental methods (single-one group pretest-posttest design with instruments such as portofolio assessment sheets, observation sheets, and  questionnaire sheets .The effectiveness of analyzing used n-gain and t-test .The subject of this research is elementary school teachers candidates who contracted “Science Learning”subject  in a program study teacher education of elementary school at University Muhammadiyah Cirebon. The findings of this study has produced a contextual book for Science teaching material. In addition, there is an increased of elementary school teachers candidates who prepared the teaching materials in a printed form relevant to the needs and characters of the students as well as the curriculum. It is proven by assessments that the ability rose significantly from 2,71 (category  is adequate skill to 3,83 (category is skilled and supported by the n-gain value  at 0,87. Based on the t-test count of 8,050 larger than t-table 2,045. Recommendations from this research is that PjBL as a learning model could become one of the alternative learning models to improve writing skills material for elementary school teachers candidates. Keyword: Project-Based-Learning, science-materials-teaching, elementary-schoo-teachers- candidates.   Abstrak: Tujuan penelitian ini untuk menganalisis efektivitas Project Based Learning (PjBL terhadap keterampilan menulis bahan ajar IPA Calon Guru SD. Penelitian ini menggunakan metode eksperimen (Single-One Group Pretest-Posttest Design dengan menggunakan instrumen berupa lembar penilaian portofolio, lembar observasi, dan lembar angket. Efektivitas dianalisis menggunakan n-gain dan uji T. Subjek penelitian ini adalah mahasiswa calon guru yang mengontrak matakuliah Pembelajaran IPA di

    11. SISTEM INFORMASI COMMUNICATION BOOK BERBASIS WEB (Studi Kasus : SD Salman Al Farisi Bandung

      Directory of Open Access Journals (Sweden)

      Fitriyani Fitriyani

      2016-03-01

      Full Text Available ABSTRAK Communication Book kini sudah menjadi istilah yang akrab di kalangan murid SD. Sebagian sekolah sudah menerapkannya sebagai sarana komunikasi antara guru dengan orangtua. Communication Book berbeda dengan rapor atau laporan reguler. Rapor dan laporan reguler biasanya diberikan pada jangka waktu tertentu, sedangkan communication book bisa digunakan kapan saja saat diperlukan. Misalnya untuk menyampaikan pengumuman yang berkaitan dengan kegiatan proses belajar-mengajar. Communication book ini bertujuan agar orangtua mengetahui kejadian di sekolah atau hal-hal yang memang harus diketahui orangtua. Misalnya, alat-alat apa yang harus dibawa anak pada hari tertentu, dan sebagainya. Namun sistem komunikasi ini masih bersifat konvensional, dimana guru menulis informasi mengenai kegiatan belajar siswa di communication book yang harus dibawa setiap hari oleh siswa, sehingga jika siswa lupa untuk membawa communication book, maka guru tidak dapat menulis informasi yang akan disampaikan. Sistem informasi ini bertujuan untuk membuat sistem informasi communication book secara online di SD Salman Al Farisi Bandung. Sistem yang dibuat berbasis PHP dan menggunakan MySQL sebagai databasenya. Sistem informasi communication book terdapat menu-menu yang dapat mendukung komunikasi antara guru dan orangtua seperti menu informasi, kegiatan, tugas, ujian, surat panggilan dan lain-lain. Diharapkan dengan penerapan sistem ini di SD Salman Al Farisi Bandung dapat membantu komunikasi secara online dan real time. Sistem informasi ini dimulai dengan merancang hubungan antara database dan proses bisnis yang terjadi di dalam web. Kemudian dilanjutkan dengan desain tampilan dan pembuatan program. Kata Kunci : Web, Php, Mysql, Communication Book. ABSTRACT The Communication book has now become a familiar term among the elementary school students. Some schools have implemented it as a means of communication between teachers and parents. Different the communication book with

    12. PENGEMBANGAN PERANGKAT PEMBELAJARAN MATERI PECAHAN BERBASIS TEORI BRUNER DI KELAS IV SD LABSCHOOL UNESA

      Directory of Open Access Journals (Sweden)

      Lina Wijayanti

      2015-07-01

      Full Text Available Penelitian ini bertujuan untuk menghasilkan perangkat pembelajaran pada materi pecahan tema 3 berbasis teori Bruner ditinjau dari kualitas produk secara umum (kevalidan, kepraktisan, dan keefektifan dan dalam peningkatan kemampuan pemecahan masalah dan prestasi belajar peserta didik di kelas IV SD Labschool Unesa. Penelitian ini termasuk penelitian dan pengembangan yang menggunakan model yang dikembangkan oleh Borg & Gall. Subjek penelitian dalam uji coba terbatas berjumlah 4 siswa, sedangkan dalam uji coba lapangan berjumlah 8 siswa. Subjek uji coba produk operasional pada kelas eksperimen sebanyak 17 siswa dan kelas kontrol sebanyak 18 siswa. Pengumpulan data dalam penelitian ini menggunakan lembar penilaian produk perangkat pembelajaran, lembar observasi guru, lembar observasi peserta didik, tes hasil belajar, angket respon guru, dan agket respon peserta didik. Analisis data menggunakan independent sample t-test dengan taraf signifikansi 0,05. Hasil penelitian menunjukkan bahwa perangkat pembelajaran hasil pengembangan dinyatakan valid dengan kategori sebagai berikut: silabus berkategori baik, RPP berkategori sangat baik, tes hasil belajar berkategori baik, dan media berkategori sangat baik, sehingga rerata hasil semua perangkat pembelajaran adalah berkategori baik. Penerapan perangkat pembelajaran secara umum dapat terlaksana dengan baik. Berdasarkan hasil uji coba kelas eksperimen dan kelas kontrol, terdapat perbedaan yang signifikan pada ketercapaian hasil belajar sehingga perangkat pembelajaran dikatakan efektif, sedangkan untuk kemampuan pemecahan masalah dan prestasi belajar siswa yang mengikuti pembelajaran menggunakan perangkat pembelajaran berbasis teori Bruner hasil pengembangan mengalami peningkatan. Kata Kunci: perangkat pembelajaran, teori Bruner, kemampuan pemecahan masalah, prestasi belajar DEVELOPING TEACHING KIT BASED ON THE THEORY OF BRUNER IN GRADE FOUR STUDENTS OF SD LABSCHOOL UNESA Abstract This study aims to develop a

    13. Clinical, hematological and genetic data of a cohort of children with hemoglobin SD

      Directory of Open Access Journals (Sweden)

      Paulo do Val Rezende

      Full Text Available ABSTRACT INTRODUCTION: The hemoglobin FSD is very uncommon in newborn screening programs for sickle cell disease. In the program of Minas Gerais, Brazil, the clinical course of children with hemoglobin SD was observed to be heterogeneous. The objective of this study was to estimate the incidence (1999-2012 and to describe the natural history of a cohort of newborns with hemoglobin SD. METHODS: Isoelectric focusing was the primary method used in newborn screening. Polymerase chain reaction-restriction fragment length polymorphism and gene sequencing were used to identify mutant alleles and for haplotyping. Gap-polymerase chain reaction was used to detect alpha-thalassemia. RESULTS: Eleven cases of hemoglobin S/D-Punjab and eight of Hb S-Korle Bu were detected. Other variants with hemoglobin D mobility were not identified. All hemoglobin D-Punjab and hemoglobin Korle Bu alleles were associated with haplotype I. Among the children with hemoglobin S/D-Punjab, there were four with the ßS CAR haplotype, six with the Benin haplotype, and one atypical. Results of laboratory tests for hemoglobin S/D-Punjab and hemoglobin S-Korle Bu were: hemoglobin 8.0 and 12.3 g/dL (p-value <0.001, leukocyte count 13.9 × 109/L and 10.5 × 109/L (p-value = 0.003, reticulocytes 7.5% and 1.0% (p-value <0.001, hemoglobin F concentration 16.1% and 6.9% (p-value = 0.001 and oxygen saturation 91.9% and 97% (p-value = 0.002, respectively. Only hemoglobin S/D-Punjab children had acute pain crises and needed blood transfusions or hydroxyurea. Those with the Benin ßS haplotype had higher total hemoglobin and hemoglobin F concentrations compared to the CAR haplotype. Transcranial Doppler was normal in all children. CONCLUSION: The clinical course and blood cell counts of children with hemoglobin S/D-Punjab were very similar to those of hemoglobin SS children. In contrast, children with hemoglobin S-Korle Bu had clinical course and blood cell counts like children with the sickle

    14. DESCRIPTION OF THE NUTRITIONAL STATUS OF STUDENTS IN SD NEGERI 3 PELIATAN, SUBDISTRICT UBUD, GIANYAR

      Directory of Open Access Journals (Sweden)

      Ayu Indah Hapsari

      2013-10-01

      Full Text Available Normal 0 false false false EN-US X-NONE X-NONE Elementary school student are the group of student that potentialy having problem with nutrition due to their eating patern and development status. The cases of malnutrition in Ubud is still highly noted even if Ubud is kown as well-developed subdistrict. The aimed of the study is to descript the nutritional status and other factors related to among the students of SD Negeri 3 Peliatan, Subdistrict Ubud, Gianyar. This study was done on August 19th 2011 until August 20th 2011 and the study design was a cross-sectional. Subjects were the grade 5th and 6th students with a total of 70 student, were chosen by quota sampling technique. Every subject was asked to administer questionnaire, to get the informaton on characteristic, eating pattern and breakfast habit. Antropometric measurements were done to gain the nutritional status of sampel. History of low birth weight was collected from the parents through administering self-administered questionnaires. The data was analysed descriptively. Result showed that subjects tend to have high malnutrition cases, in whom 25.7% were undernutrition and 24.3% were overnutrition 24.3%. Majority of subjects who have good nutritional status were those who admitted to have balanced eating pattern and breakfast habit. In addition, subjects with good nutrition status tended to have good academic scores and those with history of low birth weight seemed to have good and over nutritional status. As the students of SD Negeri 3 Peliatan seemed to have remarkable problem of malnutrition, it is suggested to inform their parents regarding the best eating pattern and to emphasize the importance of berakfast habit to achieve and maintain the good nutritional status for their children. /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso

    15. New excited states in sd-shell nucleus {sup 33}P

      Energy Technology Data Exchange (ETDEWEB)

      Fu, B.; Reiter, P.; Arnswald, K.; Hess, H.; Hirsch, R.; Lewandowski, L.; Schneiders, D.; Seidlitz, M.; Siebeck, B.; Steinbach, T.; Vogt, A.; Wendt, A.; Wolf, K. [Institut fuer Kernphysik, Universitaet zu Koeln (Germany)

      2015-07-01

      Isospin-symmetry breaking in nuclear physics is mainly described by Mirror-Energy Differences (MED) for mirror nuclei or Triplet-Energy Differences (TED) for isobaric triplets. Modified USD-calculations successfully reproduce MED for T=1,3/2,2 sd-shell nuclei. Refined tests of theory are given by lifetime measurements in order to deduce transition-strength values. In order to study the mirror pair {sup 33}Ar and {sup 33}P, the fusion-evaporation reaction {sup 13}C+{sup 26}Mg at 46 MeV was measured at the Cologne tandem accelerator and the HORUS spectrometer employing the Doppler-Shift-Attenuation-Method (DSAM). First results yielded new γ-ray transitions in {sup 33}P and {sup 33}S. The level scheme of {sup 33}P was extended up to excitation energies of 10 MeV. Spins and parities of the new levels were determined exploiting γγ-angular correlations. Together with values from the proton-rich T{sub z} = - 3/2 partner, the levels are compared to shell model calculations, describing excitation energies of sd -shell mirror pairs. The understanding of isospin symmetry and isospin-symmetry breaking is a fundamental question in nuclear physics. Isospin-symmetry breaking is mainly described by Mirror-Energy Differences (MED) for mirror nuclei or Triplet-Energy Differences (TED) for isobaric triplets. Modified USD{sup m}{sub 1,2,3}-calculations successfully reproduced MED for the mirror nuclei {sup 33}Ar and {sup 33}P. Both {sup 33}P and {sup 33}S were produced at the Cologne FN tandem accelerator employing the fusion-evaporation reaction {sup 13}C+{sup 26}Mg at 46 MeV and spectroscopically investigated using 14 HPGe detectors. Several new energy states (in {sup 33}P) and γ-ray transitions (in {sup 33}P and {sup 33}S) were detected. Spins and parities of the new levels in {sup 33}P were determined exploiting γγ-angular correlations. The level scheme of {sup 33}P was extended up to excitation energies of 10 MeV.

    16. PEMBERDAYAAN ANAK SD DALAM UPAYA PENINGKATAN KONSUMSI GARAM BERYODIUM DI DESA APUAN KECAMATAN SUSUT KABUPATEN BANGLI

      Directory of Open Access Journals (Sweden)

      Tresna Adhi K

      2012-10-01

      Full Text Available Iodine deficiency disorder (IDD is the most single common cause of preventable mental retardation and brain damage in the world. It decreases child survival, causes goiters, and impairs growth and development. Apuan Village, Bangli Regency is categorized as endemic areas (TGR=20,3% according to the definition from Health Office reports of Bali Province in 2008. One of the approaches that might be worth considering in alleviating the problem is the empowerment of elementary school children in an effort to increase the consumption of iodized salt in household. This approach aimed at empowering children to provide information to their parents on iodized salt consumption. Community services activities were conducted from December 16 to 21 October 2010 in SD 1 and SD 3 Apuan involving 62 elementary school children. The main activities were the provision of knowledge and guidance to elementary school children about the benefits of iodized salt. The first phase of the activities consists of examining the level of iodine in salt. This phase was then followed by giving the students a pre-test prior to the guidance and a post-test after the guidance for measuring the level of improvement on knowledge of elementary school children about iodized salt. The second phase was conducted one week after the first phase by measuring the level of iodine in the household salt of the same respondents. Data were analyzed using descriptive and analytical by computer program. Results pre-test and post-tests showed an increase in the knowledge for good knowledge category (0% to 31%, and moderate knowledge category (3.2% to 40.3% and while a decrease in the limited knowledge category (96.8% to 9.7%. Statistical analysis showed significant differences (p <0.05. Test results that contain iodine salt showed increased percentage of 72.6% in the first phase to 96.7% in the second phase. It can be concluded that elementary school children might become a good initiator to improve

    17. Proses Berpikir Siswa SD dalam Melakukan Estimasi Masalah Berhitung Berdasarkan Jenis Kelamin

      Directory of Open Access Journals (Sweden)

      Muh. Rizal

      2013-01-01

      Full Text Available Abstract: The Thinking Process of Primary-school Students of Different Sexes in Estimating Arithmetic Problems. This case study is intended to explore the thinking process of the fifth-year students of different sexes in estimating arithmetic problems. Two students, one male and one female, belonging to the high achievers in a mathematics test were selected for the study and then interviewed, assigned to solve arithmetic problems, and finally asked to think aloud their thinking process. The study reveals that the thinking process of both the male and female subjects is in the form of accommodation as they ap­proached the arithmetic problems by repeatedly reading the tasks. Though employing the same thinking process, in the planning stage, the male subject made use of rounding and compatible number strategies, whereas the female one used only rounding strategy. In implementing the plan, the male subject em­ployed mental counting through assimilation, but the female one used algorithm through accommoda­tion. In the evaluating stage, the male subject traced back his work through mental counting, while the female one utilized reverse operations. Abstrak: Proses Berpikir Siswa SD dalam Melakukan Estimasi Masalah Berhitung Berdasarkan Jenis Kelamin. Penelitian ini ingin mendeskripsikan proses berpikir siswa laki-laki dan perempuan yang berkemampuan matematika tinggi dalam melakukan estimasi. Penelitian dilakukan di kelas V SD, dengan subjek satu siswa laki-laki dan satu siswa perempuan yang memiliki skor 75 ke atas dalam tes kemampuan matematika. Data dikumpulkan dengan wawancara, pemberian tes dan think aloud. Analisis dilakukan dengan menelaah seluruh data, reduksi data, pengolompokan data, kategorisasi, pengkodean, dan pemeriksaan kredibilitas data dengan triangulasi waktu. Hasil penelitian menunjukkan bahwa proses berpikir keduanya adalah akomodasi. Dalam membuat rencana, laki-laki menggunakan rounding dan compatible number strategy, sedangkan

    18. EVALUASI PEMBELAJARAN ANAK BERKEBUTUHAN KHUSUS (ABK DI KELAS INKLUSIF DI SD PLUS DARUL 'ULUM JOMBANG

      Directory of Open Access Journals (Sweden)

      Lilik Maftuhatin

      2014-10-01

      Full Text Available Penelitian ini dilatarbelakangi permasalahan belum ada standar evaluasi pembelajaran yang pasti untuk anak yang memiliki kelebihan dan kekurangan, walaupun mereka mendapat pelayanan pendidikan di kelas inklusif. Karena itu penelitian ini bertujuan untuk mencari solusi pemecahan masalah bagaimana sistem perencanaan evaluasi pembelajaran, bentuk evaluasi, bentuk pelaporan hasil evaluasi yang terdapat di kelas inklusif. Penelitian ini difokuskan pada  perencanaan evaluasi pembelajaran, bentuk evaluasi yang dilakukan, dan bentuk laporan evaluasi yang telah dilakukan di kelas inklusif yang terdapat di SD Plus Darul Ulum. Penelitian ini dilakukan dengan metode interview,observasi dan dokumentasi. Obyek penelitian adalah kepala sekolah, guru-guru pendamping ABK, serta koordinator kelas inklusi disertai dengan data-data di lapangan yang dapat mendukung penelitian ini. Hasil penelitian menyimpulkan bahwa evaluasi pembelajaran sudah cukup bagus karena guru sudah menerapkan dua metode dalam evaluasi yaitu dengan soal yang disamakan dengan reguler dan yang kedua dengan soal sesuai dengan kebutuhan mereka, disertai dengan portofolio yang mencatat perkembangan mereka selama pembelajaran.This research is based on the lack of learning evaluation standard  for the children with special education need. It is based on the fact that inclusive class for them has no evaluation standard yet. Therefore, the research was used to figure out; the problem, method and the form of learning evaluation planning system. It also used to find out the result report form of learning evaluation at inclusive class, SD Plus  Darul Ulum. The focus of the research were the problem, method and the form of learning evaluation planning system. This research was done by interviewing, observation and documentation. Meanwhile the targets of the research were teachers for children with special needs, inclusion class coordinator and the supporting data.Based on the research, it can be

    19. Impact of Channel, Stress-Relaxed Buffer, and S/D Si1- x Ge x Stressor on the Performance of 7-nm FinFET CMOS Design with the Implementation of Stress Engineering

      Science.gov (United States)

      Othman, Nurul Aida Farhana; Hatta, Sharifah Fatmadiana Wan Muhamad; Soin, Norhayati

      2018-04-01

      Stress-engineered fin-shaped field effect transistors (FinFET) using germanium (Ge) is a promising performance booster to replace silicon (Si) due to its high holes mobility. This paper presents a three-dimensional simulation by the Sentaurus technology computer-aided design to study the effects of stressors—channel stress, stress-relaxed buffer (SRB), and source/drain (S/D) epitaxial stress—on different bases of FinFET, specifically silicon germanium (SiGe) and Ge-based, whereby the latter is achieved by manipulating the Ge mole fraction inside the three layers; their effects on the devices' figures-of-merits were recorded. The simulation generates an advanced calibration process, by which the drift diffusion simulation was adopted for ballistic transport effects. The results show that current enhancement in p-type FinFET (p-FinFET) with 110% is almost twice that in n-type FinFET (n-FinFET) with 57%, with increasing strain inside the channel suggesting that the use of strain is more effective for holes. In SiGe-based n-FinFET, the use of a high-strained SRB layer can improve the drive current up to 112%, while the high-strain S/D epitaxial for Ge-based p-FinFET can enhance the on-state current to 262%. Further investigations show that the channel and S/D doping are affecting the performances of SiGe-based FinFET with similar importance. It is observed that doping concentrations play an important role in threshold voltage adjustment as well as in drive current and subthreshold leakage improvements.

    20. 77 FR 27417 - Foreign-Trade Zone 220-Sioux Falls, SD; Notification of Proposed Production Activity, Rosenbauer...

      Science.gov (United States)

      2012-05-10

      ... is used for the production of emergency vehicles and firefighting equipment (pumps, tankers, rescue... drives, DC motors, static converters, rechargeable flashlights, flashlight parts, electrical foam..., LLC, (Emergency Vehicles/Firefighting Equipment), Lyons, SD The Sioux Falls Development Foundation...

    1. The Implications for the Royal Marines Command (RMC) of Operational Manoeuvre From the Sea (OMFTS) and Sea Dragon (SD)

      National Research Council Canada - National Science Library

      Maynard, A. T

      1997-01-01

      .... The United States Marine Corps, as part of a United States initiative, is developing OMFTS, a new amphibious power projection strategy, and has established SD, an experimental process to test its new...

    2. Nuclear ground state properties and self-consistent calculations with the Skyrme interaction. II. S-D shell nuclei

      International Nuclear Information System (INIS)

      Flocard, H.

      1975-04-01

      Hartree-Fock results concerning the ground state properties of some S-D shell nuclei are discussed. Two different Skyrme interactions have been used. They both lead to good agreement with the experimental total binding energies, charge radii and multipole moments. In particular the observed prolate-oblate transitions occuring in the S-D shell are reproduced. The calculated spectroscopic factors are also shown to be consistent with experimental data [fr

    3. Effect of axial tibial torque direction on ACL relative strain and strain rate in an in vitro simulated pivot landing.

      Science.gov (United States)

      Oh, Youkeun K; Kreinbrink, Jennifer L; Wojtys, Edward M; Ashton-Miller, James A

      2012-04-01

      Anterior cruciate ligament (ACL) injuries most frequently occur under the large loads associated with a unipedal jump landing involving a cutting or pivoting maneuver. We tested the hypotheses that internal tibial torque would increase the anteromedial (AM) bundle ACL relative strain and strain rate more than would the corresponding external tibial torque under the large impulsive loads associated with such landing maneuvers. Twelve cadaveric female knees [mean (SD) age: 65.0 (10.5) years] were tested. Pretensioned quadriceps, hamstring, and gastrocnemius muscle-tendon unit forces maintained an initial knee flexion angle of 15°. A compound impulsive test load (compression, flexion moment, and internal or external tibial torque) was applied to the distal tibia while recording the 3D knee loads and tibofemoral kinematics. AM-ACL relative strain was measured using a 3 mm DVRT. In this repeated measures experiment, the Wilcoxon signed-rank test was used to test the null hypotheses with p < 0.05 considered significant. The mean (±SD) peak AM-ACL relative strains were 5.4 ± 3.7% and 3.1 ± 2.8% under internal and external tibial torque, respectively. The corresponding mean (± SD) peak AM-ACL strain rates reached 254.4 ± 160.1%/s and 179.4 ± 109.9%/s, respectively. The hypotheses were supported in that the normalized mean peak AM-ACL relative strain and strain rate were 70 and 42% greater under internal than under external tibial torque, respectively (p = 0.023, p = 0.041). We conclude that internal tibial torque is a potent stressor of the ACL because it induces a considerably (70%) larger peak strain in the AM-ACL than does a corresponding external tibial torque. Copyright © 2011 Orthopaedic Research Society.

    4. New Pulse Timing Measurements of the sdBV Star CS 1246

      Directory of Open Access Journals (Sweden)

      Hutchens Zackary L.

      2017-12-01

      Full Text Available CS 1246 is a hot subdwarf B star discovered in 2009 to exhibit a single, large-amplitude radial pulsation. An O-C diagram constructed from this mode revealed reflex motion due to the presence of a low-mass M dwarf, as well as a long-term trend consistent with a decrease in the pulsational period. The orbital reflex motion was later confirmed with radial velocity measurements. Using eight years of data collected with the Skynet Robotic Telescope Network, we show that the pulsation amplitude of CS 1246 is decaying nonlinearly. We also present an updated O-C diagram, which might now indicate a positive Ṗ and a new 2.09 ± 0.05 yr oscillation consistent with orbital reflex motion of the entire inner sdB+dM binary, possibly due to the gravitational influence of a circumbinary planet with minimum mass . However, unlike the presence of the M dwarf, we hesistate to claim this object as a definitive detection since intrinsic variability of the pulsation phase could theoretically produce a similar effect.

    5. PELAKSANAAN PEMBELAJARAN BAHASA MELAYU DI SD AMANASAK KABUPATEN MUANG PATTANI THAILAND SELATAN

      Directory of Open Access Journals (Sweden)

      Hasuenah Dumeedae

      2013-01-01

      Full Text Available Penelitian ini bertujuan untuk mengungkap pelaksanaan proses pembelajaran bahasa Melayu di SD Amanasak Kabupaten Muang Pattani Thailand Selatan, meliputi pendekatan, metode, strategi tek-nik dan media pembelajaran, interaksi guru dan siswa, serta peran guru, siswa, dan materi. Penelitian ini menggunakan metode penelitian kualitatif. Subjek adalah guru, para siswa dan wakil kepala seko-lah, objek adalah pelaksanaan pembelajaran bahasa Melayu di lembaga tersebut. Teknik pengumpulan data adalah observasi berpartisipasi, wawancara, dan studi dokumentasi. Hasil penelitian ini menun-jukkan bahwa pendekatan, metode, strategi dan teknik pembelajaran yang digunakan cukup membuat siswa antusias untuk mempelajari bahasa Melayu. Media pembelajaran yang digunakan dalam labora-torium telah digunakan dengan maksimal, namun tidak sering digunakan. Interaksi guru dan siswa berjalan dengan baik, meskipun belum seluruhnya menggunakan bahasa Melayu dan bahkan penggu-naan bahasa Thai masih lebih banyak daripada bahasa Melayu. Guru telah menjalani tugasnya sebagai fasilitator, perencana, dan pengontrol dengan baik. Siswa telah diberi kesempatan untuk mencari sum-ber belajar tambahan, sementara materi yang ada cukup membuat siswa bersemangat mengikuti pem-belajaran. Pengelolaan kelas dalam belajar mengajar sudah meningkatkan hasil pembelajaran dengan efektif, dan efisien. Evaluasi proses pelajaran menggunakan tes berbahasa dari membaca, berbicara, menyimak dan menulis. Alat evaluasi sudah sesuai dengan rencana pelaksanaan pembelajaran dan kemampuan siswa yang berhubungan dengan aspek kognitif, sosial, afektif, dan personal. Pengukur ini sudah mencakup materi dan keterampilan berbahasa siswa. Kata kunci: bahasa Melayu, pelaksanaan pembelajaran

    6. De weg van Vlaamse 'daders' naar de Gestapo. De tolken van de Antwerpse Sipo-SD

      Directory of Open Access Journals (Sweden)

      Robby Van Eetvelde

      2009-01-01

      Full Text Available Flemish Collaborators and their Route to the Gestapo. The Translators of the Sipo-SD in AntwerpDuring the Second World War, Nazi-Germany used the Geheime Staatspolizei (Gestapo in its occupied territories and at the home front to maintain order and execute the racial policy of the regime. With a head office in Brussels and branches in Antwerp, Ghent, Liège and Charleroi, the Gestapo was also present in military occupied Belgium. The German agents were not completely up to their task. They lacked the knowledge of the regional languages and circumstances. The help of the local Belgian populace was therefore a necessity. What motivated these men to collaborate so assiduously with the German occupier? This research is based on the postwar criminal case files, compiled by the military courts in the context of the prosecution of those who collaborated. Several biographies of Flemish collaborators with the Gestapo office in Antwerp have been reconstructed. In this way, four major motivational groups can be distinguished: opportunists, ideological perpetrators, ‘traditional’ collaborators and former members of the resistance. Contrary to existing research into similar groups of men, financial or material gain was not their primary motive. Various psychological factors played a greater role.

    7. Designing laboratory activities in elementary school oriented to scientific approach for teachers SD-Kreatif Bojonegoro

      Science.gov (United States)

      Dwikoranto; Surasmi, W. A.; Suparto, A.; Tresnaningsih, S.; Sambada, D.; Setyowati, T.; Faqih, A.; Setiani, R.

      2018-03-01

      Important science lessons are introduced to elementary school students through inquiry. This training is important to do because one key determinant of succesful laboratory activities is teachers. This course aims to enable teachers to design an inquiry-based Laboratory Activity and be able to apply it in the classroom. The training was conducted at SD-Kreatif Bojonegoro by Modeling, Design Laboratory activities and Implementing. The results of Laboratory Activities designed to trace the seven aspects that can support the development of inquiry skills in either category. The teacher's response in this activity is positive. The conclusion of this training can improve the ability of teachers in designing and implementing laboratory activities of Science and then expected to positively affect the frequency of science laboratory activities. Usually teachers use learning by using this Laboratory Activity, it will be affected on the pattern of inquiry behavior to the students as well so that will achieve the expected goals. Teachers are expected to continue for other topics, even for other similarly characterized subjects. This habitation is important so that the teacher's skill in making Laboratory Activity continues to be well honed and useful for the students.

    8. DESAIN MATERI BANGUN DATAR MENGGUNAKAN ORIGAMI BERKONTEKS TANGRAM DI SD KELAS II

      Directory of Open Access Journals (Sweden)

      Lisnani Lisnani

      2017-05-01

      Full Text Available ABSTRACT. The study aims to improve the ability of mathematical communication in recognizing, grouping various types of flat wake. The subjects of the study were elementary school students Class IIA in SD Negeri 43 Palembang amounted to 27 people. Data collection is done through observation sheets, interviews, tests, documentation, and field notes. The research method used is a research design consisting of three stages: First stage, preliminary design / preparing for the experiment; The second stage, design experiment consisting of pilot and teaching experiment. The third stage, retrospective analysis. This study develops a series of activities and strategies that learners do on a flat wake material. The results of this study in the form of learning trajectory (learning path in each activity are: First activity, learners recognize various shapes and characteristics of wake up flat with conventional way. Then, on the second activity, learners can recognize the types and characteristics of the wake up trained by using the model match a make. Furthermore, the third activity, enhances its mathematical communication ability by using origang tangram context. Keywords : Design research, mathematical communication, make a match, origami

    9. PEMBELAJARAN SAINS SD UNTUK SISWA TUNANETRA DI SLB-A YAKETUNIS

      Directory of Open Access Journals (Sweden)

      Aprilia Eki Saputri

      2013-07-01

      Full Text Available Penelitian ini bertujuan untuk mendeskripsikan pelaksanaan pembelajaran sains SD di SLB-A Yaketunis. Penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian etnografi kelas. Data dianalisis menggunakan analisis data Miles dan Huberman yaitu: reduksi, penyajian, dan verifikasi data. Hasil penelitian menunjukkan bahwa pembelajaran sains di SLB-A Yaketunis diawali dengan analisis kebutuhan siswa. Materi pembelajaran yang dapat diwujudkan dalam bentuk konkrit dan media pembelajaran tersedia atau dapat disediakan guru, maka indera perabaanlah yang dimaksimalkan oleh guru. Sedangkan materi pembelajaran yang tidak dapat diwujudkan dalam bentuk konkrit, hanya diampaikan dengan memanfaatkan komunikasi verbal yang bersifat kontekstual. Budaya kelas di dalam pembelajaran sains di SLB-A Yaketunis adalah menumbuhkan rasa ingin tahu siswa terhadap fenomena-fenomena yang ada di alam semesta, pemanfaatan indera perabaan, dan pendengaran siswa di dalam belajar sains. Budaya tersebut dikembangkan dan dimanfaatkan sepanjang pembelajaran sains agar siswa menguasai keterampilan proses sains dasar (observasi, klasifikasi, mengukur, komunikasi, prediksi, dan inferensi untuk mempelajari fakta, konsep, prinsip, dan teori dalam mata pelajaran sains. Kata kunci: pembelajaran sains dan siswa tunanetra.

    10. Dynamic assessment for life extension of nuclear power plants (NPPs) using system dynamics (SD) method

      International Nuclear Information System (INIS)

      Woo, Tae Ho

      2012-01-01

      It has been proposed to extend the life of nuclear power plants (NPPs) for the economic purpose. Especially, the primary systems in reactor are considered in the thermohydraulic and neutronic aspect, which is related to the safety system. The electric power and the lifespan of components are expressed as economic situation. In addition, political considerations are given by the presidential change and the nuclear non-proliferation characteristics. The dynamical investigation using system dynamics (SD) shows the effective time for the life extension of the NPPs by Monte-Carlo simulations. This non-linear algorithm is incorporated with the feedback loop of the event sequences. The expected event is related to the past event, which affects to the dynamical simulations of lifetime in the NPPs. In the conclusions, the safety guarantee as well as the economic profit in the re-use of long term operated power plants is presented, which is mentioned as the transient time between 2019 and 2021 in this paper. (orig.)

    11. Mercury(II) and methyl mercury speciation on Streptococcus pyogenes loaded Dowex Optipore SD-2

      International Nuclear Information System (INIS)

      Tuzen, Mustafa; Uluozlu, Ozgur Dogan; Karaman, Isa; Soylak, Mustafa

      2009-01-01

      A solid phase extraction procedure based on speciation of mercury(II) and methyl mercury on Streptococcus pyogenes immobilized on Dowex Optipore SD-2 has been established. Selective and sequential elution with 0.1 mol L -1 HCl for methyl mercury and 2 mol L -1 HCl for mercury(II) were performed at pH 8. The determination of mercury levels was performed by cold vapour atomic absorption spectrometry (CVAAS). Optimal analytical conditions including pH, amounts of biosorbent, sample volumes, etc., were investigated. The influences of the some alkaline and earth alkaline ions and some transition metals on the recoveries were also investigated. The capacity of biosorbent for mercury(II) and methyl mercury was 4.8 and 3.4 mg g -1 . The detection limit (3 sigma) of the reagent blank for mercury(II) and methyl mercury was 2.1 and 1.5 ng L -1 . Preconcentration factor was calculated as 25. The relative standard deviations of the procedure were below 7%. The validation of the presented procedure is performed by the analysis of standard reference material (NRCC-DORM 2 Dogfish Muscle). The procedure was successfully applied to the speciation of mercury(II) and methyl mercury in natural water and environmental samples.

    12. PROBLEMATIKA PEMBELAJARAN BAHASA INDONESIA DI MI/SD DAN ALTERNATIF PEMECAHANNYA

      Directory of Open Access Journals (Sweden)

      Yuentie Sova Puspidalia

      2012-06-01

      Full Text Available Abstract: The ultimate goal of Indonesian teaching is to help learners able to integrate themselves into the society successfully. This aim is in line with the development of science and technology in the globalization era, in which the role of the Indonesian language as a mean of personal development is inevitably challenged by the rapid changes and the need of international languages. For this reason, it is worried that learners face any negative wash back of the existence of International language, in instance, the lost of their own identity. To this end, the role of Indonesian teaching is getting more and more obviously important. In reality, however, the Indonesian teaching is generally assumed as the easiest subject if it is compared with other subjects. As a result of this case, learners pretend not to learn Indonesian seriously. Ironically, many students get low grade although the Indonesian lesson is seen easily to learn. In fact, elementary school (SD/MI is regarded as basis for the formation of the noble values of the nation. The study had identified several sources of problems in learning Indonesian both from the educators or learners. Besides, it was revealed that the result of learning was affected by some aspects, such as the goals, materials, methods, school facilities and infrastructure.

    13. PENGELOLAAN AKREDITASI SEKOLAH (STUDI SITUS SD NEGERI 2 MRANTI KECAMATAN PURWOREJO KABUPATEN PURWOREJO

      Directory of Open Access Journals (Sweden)

      Supriyatno Supriyatno

      2015-07-01

      Full Text Available The onjectives of this research are to describe (1 the preparation of school self-evaluation in improving school accreditation; (2 The visitation in improving school accreditation; (3 The results of school accreditation. The type of the research is qualitative and uses ethnography design. The site of the study is SD Negeri 2 Mranti Purworejo District, Purworejo. Techniques for collecting data used are interviews, observations, and documentation. The results of this research are as follows: (1 Preparation of school self-evaluation is conducted by a special team formed by the principal. The preparation done before the new school year, it takes place by collecting data from the SNP. EDS is consisting of EDS instrument and the physical evidence for each item SNP. The preparation is conducted byhaving a checklist for each item in the SNPs form that describes the real condition of the school; (2 the visitation process in improving schools accreditation runs smoothly and according to the procedure. The process begins with the submission of the letter that comes with the implementation of the accreditation document to School Accreditation Association (BAS of district; (3 the accreditation result increases from 79 in 2005 to 86.81 in 2010.

    14. PENGEMBANGAN BUKU PENGAYAAN APRESIASI DONGENG YANG BERMUATAN CLIL BAGI PESERTA DIDIK SD KELAS TIGA

      Directory of Open Access Journals (Sweden)

      Meina Febriani

      2015-08-01

      Full Text Available Salah satu cara membelajarkan muatan budaya dan ilmu pengetahuan yakni dengan kegiatan apresiasi dongeng. Dongeng sebagai salah satu karya sastra memiliki potensi untuk menghela muatan Content Language Integrated Learning (CLIL dan ungkapan Jawa. Setelah mempelajari buku-buku apresiasi dongeng yang sudah ada, ditemukan fakta bahwa buku-buku tersebut masih belum sesuai harapan, baik dari aspek isi, penyajian, bahasa dan keterbacaan, maupun grafika. Relevan dengan situasi tersebut, diperlukan buku pengayaan apresiasi dongeng yang bermuatan CLIL yang sesuai bagi peserta didik SD kelas 3, baik dari aspek isi, penyajian, bahasa dan keterbacaan, maupun grafika. Metode yang digunakan dalam penelitian ini adalah Research andDevelopment (penelitian dan pengembangan dari Borg dan Gall. One way to learn culture and science that is the fabled appreciation activities. Fairy tale as one of the literary works have the potential to haul cargo Content Language Integrated Learning (CLIL and Java expression. After studying the books offairy tale sexisting appreciation, it was found that these books is not as expected, both from the aspect of content, presentation, language and readability, and graphics. Relevant to the situation, necessary book-laden fairy tale appreciation enrichment CLIL suitable for grade 3 students, both fromthe aspect of content, presentation, language and readability, and graphics. The method used in this study is the research and development (research and development of the Borg and Gall.

    15. Spectrum of {gamma} rays from the decay of SD to normal states in {sup 191}Hg

      Energy Technology Data Exchange (ETDEWEB)

      Gassmann, D.; Khoo, T.L.; Lauritsen, T. [and others

      1995-08-01

      In B.a.7. we propose that the statistical spectrum emitted from a sharp single excited state serves as a probe of pairing in excited states. A specific test of this proposal is the comparison of the spectra from even-even and odd-even nuclei. Whereas a pair gap exists in an even-even nucleus, it gets filled in an odd-even nucleus. Consequently, low-energy transitions can arise in the latter case, whereas they are calculated to be absent in the former case because very few levels exist in the cold gap region. In addition, transitions between 1.4 - 2.2 MeV, which {open_quotes}jump{close_quotes} across the gap, are predicted to have lower yield in the odd-even nuclei. Serendipitously, decay from a superdeformed state serves as a good initial excited sharp state. We extracted the spectrum pairwise-coincident with SD lines in {sup 191}Hg from Gammasphere data and compared it with the equivalent spectra from the even-even nuclei {sup 192,194}Hg. The differences that are predicted to occur are indeed observed. Thus, the data support our proposal that the reduction of pairing with thermal excitation energy can be probed with statistical decay spectra.

    16. Dynamic assessment for life extension of nuclear power plants (NPPs) using system dynamics (SD) method

      Energy Technology Data Exchange (ETDEWEB)

      Woo, Tae Ho [Seoul National Univ. (Korea, Republic of). Dept. of Nuclear Engineering

      2012-12-15

      It has been proposed to extend the life of nuclear power plants (NPPs) for the economic purpose. Especially, the primary systems in reactor are considered in the thermohydraulic and neutronic aspect, which is related to the safety system. The electric power and the lifespan of components are expressed as economic situation. In addition, political considerations are given by the presidential change and the nuclear non-proliferation characteristics. The dynamical investigation using system dynamics (SD) shows the effective time for the life extension of the NPPs by Monte-Carlo simulations. This non-linear algorithm is incorporated with the feedback loop of the event sequences. The expected event is related to the past event, which affects to the dynamical simulations of lifetime in the NPPs. In the conclusions, the safety guarantee as well as the economic profit in the re-use of long term operated power plants is presented, which is mentioned as the transient time between 2019 and 2021 in this paper. (orig.)

    17. Scanning PIV investigation of the laminar separation bubble on a SD7003 airfoil

      Energy Technology Data Exchange (ETDEWEB)

      Zhang, Wei [Technische Universitaet Braunschweig, Institut fuer Stroemungsmechanik, Braunschweig (Germany); Iowa State University, Department of Aerospace Engineering, Ames, IA (United States); Hain, Rainer [Technische Universitaet Braunschweig, Institut fuer Stroemungsmechanik, Braunschweig (Germany); Institut fuer Aerodynamik und Stroemungstechnik, Deutsches Zentrum fuer Luft- und Raumfahrt e.V. (DLR), Braunschweig (Germany); Kaehler, Christian J. [Technische Universitaet Braunschweig, Institut fuer Stroemungsmechanik, Braunschweig (Germany); Universitaet der Bundeswehr Muenchen, Institut fuer Stroemungsmechanik und Aerodynamik, Neubiberg (Germany)

      2008-10-15

      A laminar separation bubble occurs on the suction side of the SD7003 airfoil at an angle of attack {alpha}=4-8 and a low Reynolds number less than 100,000, which brings about a significant adverse aerodynamic effect. The spatial and temporal structure of the laminar separation bubble was studied using the scanning PIV method at {alpha}=4 and Re=60,000 and 20,000. Of particular interest are the dynamic vortex behavior in transition process and the subsequent vortex evolution in the turbulent boundary layer. The flow was continuously sampled in a stack of parallel illuminated planes from two orthogonal views with a frequency of hundreds Hz, and PIV cross-correlation was performed to obtain the 2D velocity field in each plane. Results of both the single-sliced and the volumetric presentations of the laminar separation bubble reveal vortex shedding in transition near the reattachment region at Re=60,000. In a relatively long distance vortices characterized by paired wall-normal vorticity packets retain their identities in the reattached turbulent boundary layer, though vortices interact through tearing, stretching and tilting. Compared with the restricted LSB at Re=60,000, the flow at Re=20,000 presents an earlier separation and a significantly increased reversed flow region followed by ''huge'' vortical structures. (orig.)

    18. Mercury(II) and methyl mercury speciation on Streptococcus pyogenes loaded Dowex Optipore SD-2

      Energy Technology Data Exchange (ETDEWEB)

      Tuzen, Mustafa, E-mail: m.tuzen@gmail.com [Gaziosmanpasa University, Faculty of Science and Arts, Chemistry Department, 60250 Tokat (Turkey); Uluozlu, Ozgur Dogan [Gaziosmanpasa University, Faculty of Science and Arts, Chemistry Department, 60250 Tokat (Turkey); Karaman, Isa [Gaziosmanpasa University, Faculty of Science and Arts, Biology Department, 60250 Tokat (Turkey); Soylak, Mustafa [Erciyes University, Faculty of Science and Arts, Chemistry Department, 38039 Kayseri (Turkey)

      2009-09-30

      A solid phase extraction procedure based on speciation of mercury(II) and methyl mercury on Streptococcus pyogenes immobilized on Dowex Optipore SD-2 has been established. Selective and sequential elution with 0.1 mol L{sup -1} HCl for methyl mercury and 2 mol L{sup -1} HCl for mercury(II) were performed at pH 8. The determination of mercury levels was performed by cold vapour atomic absorption spectrometry (CVAAS). Optimal analytical conditions including pH, amounts of biosorbent, sample volumes, etc., were investigated. The influences of the some alkaline and earth alkaline ions and some transition metals on the recoveries were also investigated. The capacity of biosorbent for mercury(II) and methyl mercury was 4.8 and 3.4 mg g{sup -1}. The detection limit (3 sigma) of the reagent blank for mercury(II) and methyl mercury was 2.1 and 1.5 ng L{sup -1}. Preconcentration factor was calculated as 25. The relative standard deviations of the procedure were below 7%. The validation of the presented procedure is performed by the analysis of standard reference material (NRCC-DORM 2 Dogfish Muscle). The procedure was successfully applied to the speciation of mercury(II) and methyl mercury in natural water and environmental samples.

    19. Important operational parameters of membrane bioreactor-sludge disintegration (MBR-SD) system for zero excess sludge production.

      Science.gov (United States)

      Yoon, Seong-Hoon

      2003-04-01

      In order to prevent excess sludge production during wastewater treatment, a membrane bioreactor-sludge disintegration (MBR-SD) system has been introduced, where the disintegrated sludge is recycled to the bioreactor as a feed solution. In this study, a mathematical model was developed by incorporating a sludge disintegration term into the conventional activated sludge model and the relationships among the operational parameters were investigated. A new definition of F/M ratio for the MBR-SD system was suggested to evaluate the actual organic loading rate. The actual F/M ratio was expected to be much higher than the apparent F/M ratio in MBR-SD. The kinetic parameters concerning the biodegradability of organics hardly affect the system performance. Instead, sludge solubilization ratio (alpha) in the SD process and particulate hydrolysis rate constant (k(h)) in biological reaction determine the sludge disintegration number (SDN), which is related with the overall economics of the MBR-SD system. Under reasonable alpha and k(h) values, SDN would range between 3 and 5 which means the amount of sludge required to be disintegrated would be 3-5 times higher for preventing a particular amount of sludge production. Finally, normalized sludge disintegration rate (q/V) which is needed to maintain a certain level of MLSS in the MBR-SD system was calculated as a function of F/V ratio.

    20. Hubungan Konsumsi Junk Food dengan Status Gizi Lebih pada Siswa SD Pertiwi 2 Padang

      Directory of Open Access Journals (Sweden)

      Rizki Nur Amalia

      2016-01-01

      Full Text Available AbstrakGizi lebih adalah keadaan tubuh seseorang yang mengalami berat badan berlebih karena kelebihan jumlah asupan energi yang disimpan dalam bentuk cadangan berupa lemak. Prevalensi gizi lebih pada anak di Indonesia mencapai 10,4. Salah satu faktor risiko terjadinya gizi lebih adalah kebiasaan mengonsumsi junk food. Tujuan penelitian ini adalah menentukan hubungan antara konsumsi junk food dengan status gizi lebih pada anak usia sekolah. Penelitian ini adalah penelitian analitik dengan rancangan cross sectional terhadap populasi penelitian yaitu siswa kelas 1 – 5 di SD Pertiwi 2 Padang sebanyak 250 siswa. Teknik pengambilan data dilakukan dengan menggunakan kuesioner semi kuantitatif FFQ.  Status gizi ditentukan dengan pengukuran berat badan dan tinggi badan yang hasilnya dikategorikan menggunakan standar antropometri penilaian status gizi anak menurut Depkes Indonesia. Pada hasil penelitian didapatkan bahwa siswa yang memiliki status gizi lebih hanya 23,6% dengan rata – rata IMT 16,9±3,69. Rata – rata frekuensi konsumsi junk food 4,6±2,9 kali per hari dan rata – rata asupan energi junk food 1046,5±918,4 kkal per hari. Kesimpulan penelitian ini adalah terdapat hubungan yang bermakna antara konsumsi frekuensi konsumsi junk food dengan kejadian gizi lebih (p = 0,013 dan tidak terdapat hubungan yang bermakna antara asupan energi junk food dengan kejadian gizi lebih (p = 0,120.Kata kunci: gizi lebih, junk food, FFQ AbstractOverweight is a condition of an individual who suffer from excessive weight due to an excess of energy intake stored in fat tissue. Prevalence of overweight in children in Indonesia reaches 10,4 %. One of the risk factors contributing to this condition is consuming junk food. The objective of this study was to identify the relationship of junk food consumption and overweight in students. This research is an analytic study conducted in a cross sectional design using 250  students of class 1-5 in SD Pertiwi 2 Padang

    1. Anti-jugular vein thrombotic effect of Morinda citrifolia L. [noni] in male SD rats

      Directory of Open Access Journals (Sweden)

      Mian-Ying Wang

      2011-09-01

      Full Text Available Background: Venous thromboembolism (VTE is a common and serious medical condition, which is estimably responsible for more than 300,000 hospital admissions annually in the USA. Pulmonary embolism (PE is a major complication of VTE, which contributes to 12% death of hospitalized patients. Heparin is the most common anti-coagulant, but severe allergic reactions, bleeding, and thrombocytopenia limit its use. Thus, seeking a botanical, nontoxic antithrombotic alternative is an interesting area. Morinda citrifolia L. [noni] is a medicinal plant used in folk remedies by Polynesians for over 2,000 years. It has been reported to have a broad range of therapeutic and preventive effects. The bioactivities of NJ have been continuously discovered with antioxidative, anti-inflammatory, analgesic, and immune modifying activities. Our novel hypothesis is whether NJ has an anti-venous thrombotic effect in rodents. To examine our hypothesis, this study was designed to examine the anti-thrombotic effect of NJ on the jugular vein thrombosis model induced by ferric chloride in SD rats.Material and Methods: NJ and placebo used in this study were donated by Morinda Holding Inc. NJ was formulated with grape juice and blue berry juice. Placebo was prepared by using the same procedure of NJ preparation, but without NJ in it. Thirty-six male SD rats were divided into six groups. Anti-venous thrombotic activities of 5% NJ, 10% NJ, heparin, and 10% NJ plus heparin were examined and compared with the positive and blank controls. Thrombosis was induced by application of a filter paper soaked in 50% ferric chloride on the right jugular vein. AFunctional Foods in Health and Disease 2011; 9:297-3092-cm fragment of the occluded vein (thrombus was removed and weighed after 1-hour maturation. Blood samples were collected for platelet count, aPTT, and PT tests.Results: The weight of a 2-cm fragment of normal jugular vein was 9.9 ± 2.1 mg, while the weight of the occluded vein in

    2. Stable, geochemically mediated biospheres in the Deep Mine Microbial Observatory, SD, USA

      Science.gov (United States)

      Osburn, M. R.; Casar, C. P.; Kruger, B.; Flynn, T. M.

      2017-12-01

      The terrestrial subsurface is a vast reservoir of life, hosting diverse microbial ecosystems with varying levels of connectivity to surface inputs. Understanding long term ecosystem dynamics within the subsurface biosphere is very challenging due to limitations in accessibility, sample availability, and slow microbial growth rates. The establishment of the Deep Mine Microbial Observatory (DeMMO) at the Sanford Underground Research Facility, SD, USA has allowed for bimonthly sampling for nearly two years at six sites spanning 250 to 1500 m below the surface. Here we present a time-resolved analysis of the geomicrobiology of the six DeMMO sites, which have been created from legacy mine boreholes modified to allow for controlled sampling. Our interdisciplinary approach includes analysis of passively draining fracture fluid for aqueous and gas geochemistry, DNA sequencing, microscopy, and isotopic measurements of organic and inorganic substrates. Fluid geochemistry varies significantly between sites, but is relatively stable over time for a given site, even through significant external perturbations such as drilling and installation of permanent sampling devices into the boreholes. The fluid-hosted microbial diversity follows these trends, with consistent populations present at each site through time, even through drilling events. For instance, the shallowest site (DeMMO 1) consistently hosts >30% uncharacterized phyla and >25% Omnitrophica whereas the deepest site (DeMMO 6) is dominated by Firmicutes and Bacterioidetes. Microbial diversity appears to respond to the availability of energy sources such as organic carbon, sulfate, sulfide, hydrogen, and iron. Carbon isotopic measurements reveal closed system behavior with significant recycling of organic carbon into the DIC pool. Together these observations suggest DeMMO hosts isolated subsurface microbial populations adapted to local geochemistry that are stable on yearlong timescales.

    3. Intelligent simulation of aquatic environment economic policy coupled ABM and SD models.

      Science.gov (United States)

      Wang, Huihui; Zhang, Jiarui; Zeng, Weihua

      2018-03-15

      Rapid urbanization and population growth have resulted in serious water shortage and pollution of the aquatic environment, which are important reasons for the complex increase in environmental deterioration in the region. This study examines the environmental consequences and economic impacts of water resource shortages under variant economic policies; however, this requires complex models that jointly consider variant agents and sectors within a systems perspective. Thus, we propose a complex system model that couples multi-agent based models (ABM) and system dynamics (SD) models to simulate the impact of alternative economic policies on water use and pricing. Moreover, this model took the constraint of the local water resources carrying capacity into consideration. Results show that to achieve the 13th Five Year Plan targets in Dianchi, water prices for local residents and industries should rise to 3.23 and 4.99 CNY/m 3 , respectively. The corresponding sewage treatment fees for residents and industries should rise to 1.50 and 2.25 CNY/m 3 , respectively, assuming comprehensive adjustment of industrial structure and policy. At the same time, the local government should exercise fine-scale economic policy combined with emission fees assessed for those exceeding a standard, and collect fines imposed as punishment for enterprises that exceed emission standards. When fines reach 500,000 CNY, the total number of enterprises that exceed emission standards in the basin can be controlled within 1%. Moreover, it is suggested that the volume of water diversion in Dianchi should be appropriately reduced to 3.06×10 8 m 3 . The reduced expense of water diversion should provide funds to use for the construction of recycled water facilities. Then the local rise in the rate of use of recycled water should reach 33%, and 1.4 CNY/m 3 for the price of recycled water could be provided to ensure the sustainable utilization of local water resources. Copyright © 2017 Elsevier B

    4. PENGARUH PENGGUNAAN MEDIA ANIMASI DALAM PEMBELAJARAN IPS TERHADAP MOTIVASI BELAJAR SISWA KELAS IV SD NEGERI MANNURUKI

      Directory of Open Access Journals (Sweden)

      Wahyullah Alannasir

      2016-08-01

      Full Text Available The objective of study at manuruki elementari schole greade are (1 to now the student learning motivation in social study. (2 to she if the animation media usage in social study learning of class IV SD Negeri Mannuruki? (2 how the students' motivation in learning IPS with the use of animation media Elementary School fourth grade students Mannuruki? (3 whether there is influence of media use animation in teaching social studies to students' motivation Mannuruki Elementary School fourth grade?. This research uses experimental research (true experimental design. Data collection  techniques used were: observation, interviews, and questionnaires. The analisis of the data use is deskriptif to describe to proces of learning by using animation media and the student motivation, and inferential analisis is  used to teks the risert hipotesis by using tetest. and  The results showed that: (1 The use of animation media in teaching social studies have stages of learning in which, every meeting there are three main stages were carried out by teachers namely planning, implementation and evaluation are then designed in accordance with the steps for using media animation with both categories. (2 learning motivation of students in social study on student learning motivation, before and after learning by using animation media has increased significantly ie before the treatment is in the category enough and after treatment increased student motivation with very good category. (3 the use of the animation media influence the studens’ motivation to learn at the fourth grade of mannuruki elementary school.    

    5. Alleviating anastrozole induced bone toxicity by selenium nanoparticles in SD rats

      Energy Technology Data Exchange (ETDEWEB)

      Vekariya, Kiritkumar K.; Kaur, Jasmine; Tikoo, Kulbhushan, E-mail: tikoo.k@gmail.com

      2013-04-15

      Aromatase inhibitors like anastrozole play an undisputed key role in the treatment of breast cancer, but on the other hand, various side effects like osteoporosis and increased risk of bone fracture accompany the chronic administration of these drugs. Here we show for the first time that selenium nanoparticles, when given in conjugation to anastrozole, lower the bone toxicity caused by anastrozole and thus reduce the probable damage to the bone. Selenium nanoparticles at a dose of 5 μg/ml significantly reduced the cell death caused by anastrozole (1 μM) in HOS (human osteoblast) cells. In addition, our results also highlighted that in female SD rat model, SeNPs (0.25, 0.5, 1 mg/kg/day) significantly prevented the decrease in bone density and increase in biochemical markers of bone resorption induced by anastrozole (0.2 mg/kg/day) treatment. Histopathological examination of the femurs of SeNP treated group revealed ossification, mineralization, calcified cartilaginous deposits and a marginal osteoclastic activity, all of which indicate a marked restorative action, suggesting the protective action of the SeNPs. Interestingly, SeNPs (1 mg/kg/day) also exhibited protective effect in ovariectomized rat model, by preventing osteoporosis, which signifies that bone loss due to estrogen deficiency can be effectively overcome by using SeNPs. - Highlights: ► SeNPs significantly reduce bone toxicity in anastrozole treated rats. ► SeNPs successfully prevented osteoporosis in ovariectomized rats. ► SeNP treatment lowered the levels of TRAP and increased the levels of ALKP.

    6. Alleviating anastrozole induced bone toxicity by selenium nanoparticles in SD rats

      International Nuclear Information System (INIS)

      Vekariya, Kiritkumar K.; Kaur, Jasmine; Tikoo, Kulbhushan

      2013-01-01

      Aromatase inhibitors like anastrozole play an undisputed key role in the treatment of breast cancer, but on the other hand, various side effects like osteoporosis and increased risk of bone fracture accompany the chronic administration of these drugs. Here we show for the first time that selenium nanoparticles, when given in conjugation to anastrozole, lower the bone toxicity caused by anastrozole and thus reduce the probable damage to the bone. Selenium nanoparticles at a dose of 5 μg/ml significantly reduced the cell death caused by anastrozole (1 μM) in HOS (human osteoblast) cells. In addition, our results also highlighted that in female SD rat model, SeNPs (0.25, 0.5, 1 mg/kg/day) significantly prevented the decrease in bone density and increase in biochemical markers of bone resorption induced by anastrozole (0.2 mg/kg/day) treatment. Histopathological examination of the femurs of SeNP treated group revealed ossification, mineralization, calcified cartilaginous deposits and a marginal osteoclastic activity, all of which indicate a marked restorative action, suggesting the protective action of the SeNPs. Interestingly, SeNPs (1 mg/kg/day) also exhibited protective effect in ovariectomized rat model, by preventing osteoporosis, which signifies that bone loss due to estrogen deficiency can be effectively overcome by using SeNPs. - Highlights: ► SeNPs significantly reduce bone toxicity in anastrozole treated rats. ► SeNPs successfully prevented osteoporosis in ovariectomized rats. ► SeNP treatment lowered the levels of TRAP and increased the levels of ALKP

    7. [Over-expression of BDNF inhibits angiotensin II-induced apoptosis of cardiomyocytes in SD rats].

      Science.gov (United States)

      Cao, Jingli; Wu, Yingfeng; Liu, Geming; Li, Zhenlong

      2018-03-01

      Objective To investigate the role and molecular mechanism of brain-derived neurotrophic factor (BDNF) against the process of cardiomyocyte hypertrophy and apoptosis. Methods Cardiomyocyte hypertrophy were estabolished by angiotensin II (Ang II) in neonatal cardiomyocytes in vitro and incomplete ligature of abdominal aorta of SD rats in vivo. BDNF over-expressing recombinant vector pcDNA5-BDNF was transfected into cardiomyocytes by liposomes. Immunofluorescence staining was used to detect the effect of BDNF transfection on the surface area of myocardial cells. The effect of BDNF transfection on the apoptosis of cardiomyocytes was assayed by flow cytometry. Real-time fluorescent quantitative PCR was performed to detect the effect of over-expression of BDNF on the expressions of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) mRNAs in cardiomyocytes. Western blot assay was used to observe the changes of BDNF, ANP and BNP, calmodulin kinase 2 (CaMK2) and phosphorylated calmodulin kinase 2 (p-CaMK2), calcineurin (CaN), p-CaN, nuclear factor of activated T cells 3 (NFATC3) and p-NFATC3 protein expressions in the myocardial tissues and cardiomyocytes. Results The expression of BDNF protein increased significantly in cardiac hypertrophy animal and cell models in a time-dependent manner. Compared with the untransfected control cardiomyocytes, the surface area of cardiomyocytes, the rate of apoptosis, the levels of ANP and BNP mRNA and protein expression, the levels of p-CaMK2 and CaN protein in the BDNF over-expressed cardiomyocytes were remarkably reduced, while the level of p-NFATC3 protein rose significantly. Conclusion BDNF inhibits the apoptosis of cardiomyocytes induced by Ang II, and it plays the role by inhibiting CaMK2 and CaN signaling pathways.

    8. READING, PREPROCESSING OF ACCELERATIONS AND CORNERS INCLINATION WITH MPU-6050 I RECORD THEM ON SD-CARD THE ARDUINO DUE

      Directory of Open Access Journals (Sweden)

      V. G. Mikhailov

      2016-01-01

      Full Text Available The short review of microcontrollers of family Arduino, their characteristics and application fields is given. Importance of record of parameters of researched object is marked to produce debugging of control systems on microcontrollers Arduino. Unique possibility of registration of parameters in family Arduino is record on SD a card in an alpha mode with usage of functions print (, write (. The problems connected to record of the binary data on SD a card on microcontroller Arduino Due are considered. The analysis of methods of record of the binary data on SD-card Arduino Due, originating problems with neocleaning of memory from the previous program leading to possibility of duplication of the data on SD to a card, presence of the erratic point of view about restriction of volumes of data record and necessity of usage become outdated SD-cards is carried out. Ways of elimination of the marked lacks are considered. The estimation of high-speed performance of various approaches of a data recording on SD a card is led. On the basis of the led researches the approach of multiplexing of the writeable information at the expense of conversion of the binary data is offered is byte-serial in a character array in code ASCI without magnification of their volume and record by units on 240 byte. It allows to use as much as possible standard function possibilities write ( Arduino and specificity of the organization of memory SD of cards and to increase high-speed performance more than in 1100 times in comparison with record in a character type on one byte.It is marked that usage of decisions of an exception of duplication of the data offered at forums does not provide completeness of their elimination. For Arduino Due for storage cleaning it is necessary usages of the special programmator or setting of the new program of loading.

    9. Strain-Modulated Epitaxy

      National Research Council Canada - National Science Library

      Brown, April

      1999-01-01

      Strain-Modulated Epitaxy (SME) is a novel approach, invented at Georgia Tech, to utilize subsurface stressors to control strain and therefore material properties and growth kinetics in the material above the stressors...

    10. Hamstring strain - aftercare

      Science.gov (United States)

      Pulled hamstring muscle; Sprain - hamstring ... There are 3 levels of hamstring strains: Grade 1 -- mild muscle strain or pull Grade 2 -- partial muscle tear Grade 3 -- complete muscle tear Recovery time depends ...

    11. Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-Dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission.

      Science.gov (United States)

      Church, Jessica D; Omer, Saad B; Guay, Laura A; Huang, Wei; Lidstrom, Jessica; Musoke, Philippa; Mmiro, Francis; Jackson, J Brooks; Eshleman, Susan H

      2008-10-01

      Single-dose nevirapine (SD NVP) at birth plus NVP prophylaxis for the infant up to 6 weeks of age is superior to SD NVP alone for prevention of vertical transmission of human immunodeficiency virus (HIV) through breastfeeding. We analyzed NVP resistance in HIV-infected Ugandan infants who received either SD NVP or extended NVP prophylaxis. We tested plasma HIV by using a genotyping assay (ViroSeq; Celera Diagnostics), a phenotypic resistance assay (PhenoSense; Monogram Biosciences), and sensitive point mutation assay (LigAmp, for K103N, Y181C, and G190A). When infants were 6 weeks old, ViroSeq detected NVP resistance in a higher proportion of infants in the extended NVP arm than in the SD NVP arm (21 of 25 [84%] vs. 12 of 24 [50%]; P = .01). Similar results were obtained with LigAmp and PhenoSense. In both study arms, infants who were HIV infected at birth frequently had NVP resistance detected. In contrast, infants in the extended NVP arm who were HIV infected after birth were more likely to have resistance detected at 6 weeks, compared with infants in the SD NVP arm. The use of extended NVP prophylaxis was also associated with detection of NVP resistance by ViroSeq at 6 months (7 of 7 [100%] infants in the extended NVP arm had resistance detected, compared with 1 of 6 [16.7%] infants in the SD NVP arm; P = .005). The use of extended NVP prophylaxis was associated with increased selection for and persistence of NVP resistance in HIV-infected Ugandan infants.

    12. Leveraging master-slave OpenFlow controller arrangement to improve control plane resiliency in SD-EONs.

      Science.gov (United States)

      Chen, Xiaoliang; Zhao, Bin; Ma, Shoujiang; Chen, Cen; Hu, Daoyun; Zhou, Wenshuang; Zhu, Zuqing

      2015-03-23

      In this paper, we study how to improve the control plane resiliency of software-defined elastic optical networks (SD-EONs) and design a master-slave OpenFlow (OF) controller arrangement. Specifically, we introduce two OF controllers (OF-Cs), i.e., the master and slave OF-Cs, and make them work in a collaborative way to protect the SD-EON against controller failures. We develop a controller communication protocol (CCP) to facilitate the cooperation of the two OF-Cs. With the CCP, the master OF-C (M-OF-C) can synchronize network status to the slave OF-C (S-OF-C) in real time, while S-OF-C can quickly detect the failure of M-OF-C and take over the network control and management (NC&M) tasks timely to avoid service disruption. We implement the proposed framework in an SD-EON control plane testbed built with high-performance servers, and perform NC&M experiments with different network failure scenarios to demonstrate its effectiveness. Experimental results indicate that the proposed system can restore services in both the data and control planes of SD-EON jointly while maintaining relatively good scalability. To the best of our knowledge, this is the first demonstration that realizes control plane resiliency in SD-EONs.

    13. The measurement of digital systolic blood pressure by strain gauge technique

      DEFF Research Database (Denmark)

      Nielsen, P E; Bell, G; Lassen, N A

      1972-01-01

      The systolic blood pressure on the finger, toe, and ankle has been measured by a strain gauge technique in 10 normal subjects aged 17-31 years and 14 normal subjects aged 43-57 years. The standard deviation in repeated measurements lies between 2 and 6 mm Hg. The finger pressure in the younger...... group was significantly higher than the corresponding arm pressure (+ 9.3 mm Hg, S.D. 6.8), but equalled this in the older group (- 0.5 mm Hg, S.D. 6.6). In the two groups the ankle pressures were + 19.3 mm Hg (S.D. 7.5) and + 23.6 mm Hg (S.D. 9.5) higher than the systolic arm pressures. The toe...... pressures were lower than the arm pressures, in the two groups - 4.8 mm Hg (S.D. 6.6) and - 9.8 mm Hg (S.D. 10.7) respectively. The ankle-toe gradient was in the younger group 24.3 mm Hg (S.D. 7.3) and in the older group 33.3 mm Hg (S.D. 12.1). Using mean minus 2.5 X S.D. as the lower limit of normality...

    14. IMPLEMENTASI KEBIJAKAN SEKOLAH DASAR INKLUSI ( Studi Kualitatif Deskriptif pada SD Inklusif di Jakarta Utara

      Directory of Open Access Journals (Sweden)

      Kurniawan *

      2017-06-01

      . Implementation of inclusion policies relating dengaan good that the management of inclusion can work well. Obstacles encountered in the implementation of policies and management penyelnggaraan inclusion operationally related standards. To that end, the government should formulate a policy SD. Inclusion in accordance with the needs of the community. Step - steps to address implementation bottlenecks inclusion policy administration and management to increase and improve learning facilities and infrastructure, providing special anggran maximum inclusion, increase the quality and quantity of teachers in accordance with department inclusions. To be recommended in order to implement the policy administration and management should be the maximum.

    15. PFOS prenatal exposure induce mitochondrial injury and gene expression change in hearts of weaned SD rats

      International Nuclear Information System (INIS)

      Xia, Wei; Wan, Yanjian; Li, Yuan-yuan; Zeng, Huaicai; Lv, Ziquan; Li, Gengqi; Wei, Zhengzheng; Xu, Shun-qing

      2011-01-01

      Xenobiotics exposure in early life may have adverse effects on animals' development through mitochondrial injury or dysfunction. The current study demonstrated the possibility of cardiac mitochondrial injury in prenatal PFOS-exposed weaned rat heart. Pregnant Sprague-Dawley (SD) rats were exposed to perfluorooctane sulfonate (PFOS) at doses of 0.1, 0.6 and 2.0 mg/kg/d and 0.05% Tween 80 as control by gavage from gestation days 2-21. The dams were allowed to give nature delivery and then heart tissues from weaned (postnatal day 21) offspring rats were analyzed for mitochondrial injury through ultrastructure observation by electron microscope, global gene expression profile by microarray, as well as related mRNA and proteins expression levels by quantitative PCR and western blot. Ultrastructural analysis revealed significant vacuolization and inner membrane injury occurred at the mitochondria of heart tissues from 2.0 mg/kg/d dosage group. Meanwhile, the global gene expression profile showed significant difference in level of some mRNA expression associated with mitochondrial function at 2.0 mg/kg/d dosage group, compared to the control. Furthermore, dose-response trends for the expression of selected genes were analyzed by quantitative PCR and western blot analysis. The selected genes were mainly focused on those encoding for proteins involved in energy production, control of ion levels, and maintenance of heart function. The down-regulation of mitochondrial ATP synthetase (ATP5E, ATP5I and ATP5O) implicated a decrease in energy supply. This was accompanied by down-regulation of gene transcripts involved in energy consumption such as ion transporting ATPase (ATP1A3 and ATP2B2) and inner membrane protein synthesis (SLC25A3, SLC25A4, SLC25A10, SLC25A29). The up-regulation of gene transcripts encoding for uncoupling proteins (UCP1 and UCP3), epidermal growth factor receptor (EGFR) and connective tissue growth factor (CTGF), was probably a protective process to maintain

    16. Radioprotective effect of calorie restriction in Hela cells and SD rats

      International Nuclear Information System (INIS)

      Yang Yang; Chong Yu; Jiao Yang; Xu Jiaying; Fan Saijun

      2012-01-01

      Objective: To explore the effect of low calorie metabolism on the survival of HeLa cells exposed to X-rays, and the influence of starvation on the antioxidative factors in the blood of rats after irradiation. Methods: MTT method was used to evaluate the impact of different concentration glucose on the proliferation of HeLa cells. Colony formation assay was employed to detect the influence of glucose (1, 5, 10 and 25 mmol/L) on radiosensitivity of HeLa cells. Flow cytometry assay was used to analyze distribution of cell cycle and apoptosis. 60 male SD rats were randomly divided into 6 groups with 10 rats each. Rats in every two groups were fed ad libitum, fasted for 24 h and fasted for 48 h, respectively. Rats in one group of each approach were respectively exposed to whole-body X-rays at 11 Gy. At 2 h after irradiation,all of rats were sacrificed and their venous blood was collected. Elisa kits were used to detect superoxide dismutase (SOD) and total antioxidant capacity (T-AOC). Results: An increased viability was observed in HeLa cells treated with the glucose at low concentration (<25 mmol/L), while HeLa cell growth was inhibited by glucose at doses of >25 mmol/L. Relevant to cells treated with 1 mmoL/L glucose, SERs (sensitive enhancement ratio) in cells exposed to 5, 10 and 25 mmol/L glucose were 1.07, 1.10 and 1.23,respectively. A reduction of G 2 /M and S arrests and apoptosis caused by 6 Gy X-ray irradiation were observed [(49.68 ±1.88)% and (35.54±1.45)% at G 2 /M phase, (16.88 ±1.22)% and (10.23 ±1.65)% at S phase, t=10.42, 5.61, P<0.05] and in the cells treated with 1 mmol/L glucose compared with cells treated with 25 mmol/L glucose [(25.50 ± 0.95)% and (7.56 ± 1.07)%, t=21.72, P<0.05].Without irradiation, calorie restriction exhibited a negligible influence on SOD and T-AOC in rats. However, after 11 Gy irradiation, compared with rats fed ad libitum, the levels of SOD and T-AOC were significantly increased in rats with calorie restriction (t=40

    17. Japon Balığı (Carassius Auratus L. 1758) ve Arpa Bitkisinin (Hordeum Vulgare L.) Gelişimi ve Su Kalitesinin İyileştirilmesi Üzerine Aquaponik Sistemin Etkileri

      OpenAIRE

      KESKİNBALTA, Mehmet Anıl; HAMZAOĞLU, Gökhan; ÇELİK, Meryem Yeşim; DERNEKBAŞI, Seval

      2015-01-01

      Bu araştırmada, Japon balığı (Carassius auratus L. 1758) ve arpa bitkisi (Hordeum vulgare L.) kullanılarak model bir akuaponik sistem oluşturulmuştur. Araştırma süresince arpa bitkisinin suyun nitrit, nitrat ve fosfat değerlerinde yaptığı değişim ve balıkların gelişimi üzerindeki etkilerinin belirlenmesi amaçlanmıştır. 30 günlük araştırma süresince günlük olarak pH, sıcaklık ve oksijen değerleri ölçülmüştür. Haftalık olarak bitki yetiştirme yatağına giren ve bitkiden süzülen suyun nitrit (NO2...

    18. Japon Balığı (Carassius auratus L. 1758) ve Arpa Bitkisinin (Hordeum vulgare L.) Gelişimi ve Su Kalitesinin İyileştirilmesi Üzerine Aquaponik Sistemin Etkileri

      OpenAIRE

      KESKİNBALTA, Mehmet; HAMZAOĞLU, Gökhan; ÇELİK, Meryem; DERNEKBAŞI, Seval

      2015-01-01

      Bu araştırmada, Japon balığı (Carassius auratus L. 1758) ve arpa bitkisi (Hordeum vulgare L.) kullanılarak model bir akuaponik sistem oluşturulmuştur. Araştırma süresince arpa bitkisinin suyun nitrit, nitrat ve fosfat değerlerinde yaptığı değişim ve balıkların gelişimi üzerindeki etkilerinin belirlenmesi amaçlanmıştır. 30 günlük araştırma süresince günlük olarak pH, sıcaklık ve oksijen değerleri ölçülmüştür. Haftalık olarak bitki yetiştirme yatağına giren ve bitkiden süzülen suyun nitrit (NO2...

    19. Preliminary screening of Ni(II metal tolerance and dye-decolorizing by Nocardiopsis sp. SD8

      Directory of Open Access Journals (Sweden)

      Ramasamy Thangaraj

      2016-04-01

      Full Text Available Objective: To reveal the screening of metal tolerance and dye-decolorizing of Nocardiopsis sp. Methods: NiSO4 and Congo red dye were used for evaluating the metal tolerance and dyedecolorizing of the randomly selected actinobacterial isolates. Results: Nocardiopsis sp. SD8 showed a better efficiency in Ni(II tolerance, though a longer lag phase was observed for this microorganism grown for 7 days in integrated mismatch negativity. Interestingly, we also found that Nocardiopsis sp. SD8 had dye-decolorizing, hemolytic, lipase and protease activity. Conclusions: The present results revealed the bioremediation of metal resistant and diverse properties of Nocardiopsis sp. SD8 and further investigations are needed to extract and identify the potent molecule.

    20. A strain gauge

      DEFF Research Database (Denmark)

      2016-01-01

      The invention relates to a strain gauge of a carrier layer and a meandering measurement grid positioned on the carrier layer, wherein the strain gauge comprises two reinforcement members positioned on the carrier layer at opposite ends of the measurement grid in the axial direction....... The reinforcement members are each placed within a certain axial distance to the measurement grid with the axial distance being equal to or smaller than a factor times the grid spacing. The invention further relates to a multi-axial strain gauge such as a bi-axial strain gauge or a strain gauge rosette where each...... of the strain gauges comprises reinforcement members. The invention further relates to a method for manufacturing a strain gauge as mentioned above....

    1. Influence of the method of optimizing adjustments of ARV-SD on attainable degree of system stability. Vliyaniye metoda optimizatsii nastroyek ARV-SD na dostizhimuyu stepen ustoychivosti sistemy

      Energy Technology Data Exchange (ETDEWEB)

      Gruzdev, I.A.; Trudospekova, G.Kh.

      1983-01-01

      An examination is made of the efficiency of the methods of successive and simultaneous optimization of adjustments of ARV-SD (ARV of strong action) of several PP. It is shown that with the use of the method of simultaneous optimization for an idealized model of complex EPS, it is possible to attain absolute controllability of the degree of stability.

    2. Resiliency to social defeat stress relates to the inter-strain social interaction and is influenced by season variation.

      Science.gov (United States)

      Han, Qiuqin; Yang, Liu; Liu, Yan; Lv, Ning; Yu, Jin; Wu, Gencheng; Zhang, Yuqiu

      2014-02-21

      Exposure to social defeat (SD) stress exerts social avoidance and depressive disorders. Little is known about the relationship between resiliency to stressors and the inter-strain social interaction (SI) level. We hypothesized that SD resiliency is correlated with a high SI between the same strain. C57BL/6J mice experienced a 10-day period of SD stress by repeated CD-1 mice offensive. The susceptible mice exhibited significant social-avoidance behaviors with less time in interaction-zone (IZ) and lower social interaction ratio (SIR) toward the Target (CD-1 mice), while resilient ones exhibited similar social interaction to control mice. When the Target was C57BL/6J mouse, either susceptible or resilient mice spent more time in IZ and the inter-strain SI in the resilient group was significantly higher than the susceptible. Correlation analysis revealed a significantly non-zero slope of the linear relationship between SIRs toward two strains. But different groups had a similar baseline of the inter-strain SI before stress, indicating a SD-induced defect in both types of SI. In addition, in four different seasons, animals exhibited a significant resiliency to the stress in summer. These data suggest that SD resiliency is related to a higher SI toward the same-strain, and may be regulated by seasonal variations. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

    3. Karolinska Psychodynamic Profile for Sexual Disorders: KAPP-SD. A proposal for a psychodynamic rating scale for sexual disorders.

      Science.gov (United States)

      Soldati, Lorenzo; Köhl, John; Abraham, Georges; Bianchi Demicheli, Francesco; Wilczek, Alexander

      2015-01-01

      Our first objective in this paper was to review the literature on psychodynamic rating scales of sexual disorders. Our second objective, based on the findings from our review, was to develop a psychodynamic rating scale for people with sexual disorders: the KAPP-SD. We developed the KAPP-SD by modifying an existing psychodynamic rating scale, which assesses stable modes of mental functioning and character traits, the Karolinska Psychodynamic Profile (KAPP). We removed items 13 and 14 of the KAPP and replaced them with three other items-sexual fantasies, conceptions and role of gender identity, and conceptions and role of sexual orientation. These items are part of the assessment of an individual's sexuality and are used to evaluate a person with a sexual disorder psychodynamically. The KAPP-SD, a modified version of the KAPP, can be found in the Appendix. We developed the KAPP-SD in order to help sex therapists make a rigorous psychodynamic evaluation of persons with sexual disorders, which would give information on the prognosis and on the type of treatment to offer.

    4. Densities, form factors, transitions and multipole moments in the s-d shell, with the Skyrme force

      International Nuclear Information System (INIS)

      Oliveira, D.R. de; Mizrahi, S.S.

      1977-09-01

      The nuclear densities, radii, multipole moments, form-factors and transition probabilities obtained for the A = 4n type of nuclei in the s-d shell are reported, using the Hartree-Fock wave functions calculated with the Skyrme force. Experimental data and theoretical values derived by others are shown for comparison [pt

    5. Three dimensional strained semiconductors

      Science.gov (United States)

      Voss, Lars; Conway, Adam; Nikolic, Rebecca J.; Leao, Cedric Rocha; Shao, Qinghui

      2016-11-08

      In one embodiment, an apparatus includes a three dimensional structure comprising a semiconductor material, and at least one thin film in contact with at least one exterior surface of the three dimensional structure for inducing a strain in the structure, the thin film being characterized as providing at least one of: an induced strain of at least 0.05%, and an induced strain in at least 5% of a volume of the three dimensional structure. In another embodiment, a method includes forming a three dimensional structure comprising a semiconductor material, and depositing at least one thin film on at least one surface of the three dimensional structure for inducing a strain in the structure, the thin film being characterized as providing at least one of: an induced strain of at least 0.05%, and an induced strain in at least 5% of a volume of the structure.

    6. Strain measurement technique

      International Nuclear Information System (INIS)

      1987-01-01

      The 10 contributions are concerned with selected areas of application, such as strain measurements in wood, rubber/metal compounds, sets of strain measurements on buildings, reinforced concrete structures without gaps, pipes buried in the ground and measurements of pressure fluctuations. To increase the availability and safety of plant, stress analyses were made on gas turbine rotors with HT-DMS or capacitive HT-DMS (high temperature strain measurements). (DG) [de

    7. Strained Silicon Photonics

      Directory of Open Access Journals (Sweden)

      Ralf B. Wehrspohn

      2012-05-01

      Full Text Available A review of recent progress in the field of strained silicon photonics is presented. The application of strain to waveguide and photonic crystal structures can be used to alter the linear and nonlinear optical properties of these devices. Here, methods for the fabrication of strained devices are summarized and recent examples of linear and nonlinear optical devices are discussed. Furthermore, the relation between strain and the enhancement of the second order nonlinear susceptibility is investigated, which may enable the construction of optically active photonic devices made of silicon.

    8. Sığır Etinde Su Tutma Kapasitesi ve Serbest Su Oranı Değişimi Üzerine bir Araştırma

      Directory of Open Access Journals (Sweden)

      Aydın Öztan

      2015-02-01

      Full Text Available Kesimden sonra ette pH değişimi, etin serbest su oranı ve su tutma kapasitesinin belirlenmesinde en önemli kriterdir. Bu araştırmada; 12 adet sığır karkasında M. Trapezius kasında kesimde, kesimden 1 saat 24 saat ve 48 saat sonra pH ölçümleri yapılmış, kompressium yöntemi ile serbest su oranı ve üç farklı yöntemle su tutma kapasitesi saptanmıştır. Pres yönteminde; süzgeç kağıtlarında toplam su alanı (T ve et alanı (Ev ek scanner ile taranmış, bilgisayarda alan ölçümleri yapılmıştır. PH-değeri bakımından zaman ve hayvan değişkenleri önemli bulunmuştur. Ette serbest su oranı rigor mortis döneminde (24 saat artmış, daha sonra düşmeye başlamıştır. Örneklerde su tutma kapasitesi kesimden başlayarak olgunlaşma periyodunda rigor mortis sonuna kadar düşmüş, daha sonra yükselmeye başlamıştır.

    9. A strain gauge

      DEFF Research Database (Denmark)

      2017-01-01

      The invention relates to a strain gauge of a carrier layer and a meandering measurement grid (101) positioned on the carrier layer, wherein the measurement grid comprises a number of measurement grid sections placed side by side with gaps in between, and a number of end loops (106) interconnecting...... relates to a method for manufacturing a strain gauge as mentioned above....

    10. Simultaneous consideration of TQM and TPM influence on production performance: A case study on multicolor offset machine using SD Model

      Directory of Open Access Journals (Sweden)

      Nagaraj H. Kamath

      2016-09-01

      Full Text Available An attempt is made in this research to show the relevance of System Dynamics (SD as a tool for simultaneously considering TQM and TPM environment in a offset machine of a commercial printing press. By controlling the TQM and TPM variables, this model will attempt to simulate or predict the behavior of an efficient printing operation. Identifying other scenarios pertaining to Human factors, affecting the socio-technical variables is the future research work of this paper. The practical implication concerns the efficient decision making system in multi-colour sheet feed offset printing, by controlling the socio-technical variables. This is a novel approach of combining different socio-technical variables SD and Cased based approach for obtaining a productive environment in print operation called “Total Production Management”.

    11. [SD-OCT As screening test for hydroxychloroquine retinopathy: The «flying saucer» sign].

      Science.gov (United States)

      Asensio-Sánchez, V M

      2015-07-01

      Two asymptomatic women treated with hydroxychloroquine 200mg every day for 8 and 16 years developed retinal toxicity. Patient 1 was found to have a normal fundus and autofluorescence examination. Patient 2 was found to have a completely normal fundus examination. Fluorescein angiography shows parafoveal hyperfluorescence, and autofluorescence shows a minimal decrease in signal in the same region. In both patients the SD-OCT shows disruption of the ellipsoid zone in parafoveal region («flying saucer» sign). SD-OCT findings in the retina can identify hydroxychloroquine retinopathy in asymptomatic patients. Copyright © 2013 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.

    12. Effect of Ganfukang on liver function and serum hepatic fibrosis markers levels in SD rats with experimental hepatic fibrosis

      International Nuclear Information System (INIS)

      Che Ying; Wang Shanju; Xu Tingting; Jiang Miaona; Jia Yujie

      2004-01-01

      Objective: To observe the effect of Ganfukang on liver function and serum hepatic fibrosis markers levels in SD rats with experimental hepatic fibrosis. Methods: SD rat models of liver fibrosis was induced by CCl 4 (n=57). Liver function (GPT, GOT) and serum hepatic fibrosis markers levels (HA, LN, C-IV, PC-III, with RIA) were tested in these models and 10 control rats. Eleven model rats were left untreated, the others were treated with Ganfukang of different concentrations and the above hepatic parameters were again determined after completion of treatment. Results: Lever function was much deteriorated and serum markers levels significantly increased in the model rats (vs controls, P<0.01). After treatment with Ganfukang, the improvement was significant (vs untreated models, P<0.01). Conclusion: Ganfukang is of definite therapeutic value for experimental hepatic fibrosis in rat models. (authors)

    13. Uniaxial Pressure Effect on the SdH Oscillations in Heavy-Fermion Semimetal CeRu4Sb12

      International Nuclear Information System (INIS)

      Saha, S. R.; Kobayashi, M.; Sugawara, H.; Namiki, T.; Abe, K.; Aoki, Y.; Sato, H.

      2003-01-01

      We report the first successful Shubnikov-de Haas (SdH) experiment under uniaxial pressure in the anomalous heavy-fermion semimetal CeRu 4 Sb 12 . The nature of the quantum oscillations in the magnetoresistance is found to be significantly sensitive to uniaxial pressure. The results reveal that the nearly spherical Fermi surface elongates along the direction of the uniaxial pressure. (author)

    14. TINJAUAN KRIMINOLOGIS TERHADAP KEJAHATAN PENYEBARAN VIDEO PORNO (Studi Kasus di Kota Makassar Tahun 2010 s/d 2013)

      OpenAIRE

      DEVANI. K, PUTRI

      2014-01-01

      - PUTRI DEVANI. K. (B 111 06 644). Tinjauan Kriminologis Terhadap Kejahatan Penyebaran Video Porno (Studi Kasus di Kota Makassar Tahun 2010 s/d 2013). Penelitian ini bertujuan untuk mengetahui faktor-faktor yang menyebabkan terjadinya penyebaran video porno di kota Makassar serta untuk mengetahui upaya pemberantasan penyebaran video porno di kota Makassar. Pelaksanaan penelitian ini dilaksanakan di Polrestabes Makassar dan Makassar Trade Centre (MTC). Untuk Polrestabes karena pada le...

    15. Implementasi Kebijakan Pembelajaran Tematik Terpadu Kurikulum 2013 di SDN Kauman 1 Malang dan SD Muhammadiyah 1 Malang

      Directory of Open Access Journals (Sweden)

      . Mulyadin

      2016-07-01

      Full Text Available Abstrak: Implementasi Kebijakan Pembelajaran Tematik Terpadu Kurikulum 2013 di SDN Kauman 1 Malang dan SD Muhammadiyah 1 Malang. Tujuan penelitian ini yaitu untuk mendeskripsikan dan menganalisis implementasi kebijakan pembelajaran tematik terpadu yang dilihat dari perencanaan pembelajaran, pelaksanaan pembelajaran, penilaian hasil pembelajaran, dan pengawasan pembelajaran di SDN Kauman 1 Malang dan SD Muhammadiyah 1 Malang. Metode yang digunakan dalam penelitian ini adalah pendekatan kualitatif dan dibantu menggunakan data statistitik dengan rancangan penelitian deskriptif. Data dalam penelitian ini diambil dari hasil kuesioner dan wawancara pada responden dan observasi pelaksanaan pembelajarannya. Subjek penelitian ini adalah Kepala Sekolah, Wakil Kepala Sekolah Bidang Kurikulum dan Guru. Berdasarkan data hasil penelitian bahwa implementasi kebijakan pembelajaran tematik terpadu kurikulum 2013 di SDN Kauman 1 Malang dan SD Muhammadiyah 1 Malang sudah dikategorikan baik, hal ini dilihat dari aspek penguasaan, pemahaman dan kemampuan guru dalam proses perencanaan pembelajaran, pelaksanaan pembelajaran, dan penilaian hasil belajar begitupun pada proses pengawasan yang dilakukan oleh kepala sekolah sudah berjalan maksimal sesuai dengan tugas dan tanggung jawabnya seperti yang ada pada Peraturan Menteri Pendidikan dan Kebudayaan (Permendikbud Republik Indonesia Nomor 65 Tahun 2013 tentang Standar Proses Pendidikan Dasar dan Menengah. Kata Kunci: Implementasi, Pembelajaran Tematik Terpadu dan Kurikulum 2013

    16. SD OCT Features of Macula and Silicon Oil–Retinal Interface in Eyes Status Post Vitrectomy for RRD

      Directory of Open Access Journals (Sweden)

      Manish Nagpal

      2015-03-01

      Full Text Available Aim: To objectively document findings at the Silicon oil-Retinal interface, macular status and tamponade effect in Silicon Oil (SO filled eyes using SD OCT. Methods: 104 eyes of 104 patients underwent SD OCT examination, horizontal and vertical macular scans, in silicone oil filled eyes which underwent silicone oil injection post vitrectomy for rhegmatogenous retinal detachment. Findings were divided into 3 Groups; Group A: Findings at silicon oil retinal interface, Group B: Macular pathology and Group C: Tamponade effect. Group C was further divided into two groups; Group 1: Complete tamponade and Group 2: Incomplete tamponade. Results: Group A: subsilicon epiretinal membranes N = 17 (16.3%, emulsified silicon oil N = 16 (15.4% Group B: foveal thickening N = 22 (21.2%, foveal thinning N = 6 (5.7%, subfoveal fluid N = 8 (7.6%, macular hole N = 2 (1.9%; Group C: Incomplete tamponade was noted in N = 12 (11.5%, complete tamponade N = 92 (88.5%.10 out of 104 eyes (9.6% had recurrent retinal detachment post silicon oil removal. 8 of these eyes had complete tamponade and 2 had incomplete tamponade. Conclusion: SD OCT is a useful tool to assess the SO–Retina interface, tamponade effect and macular pathology in SO filled eyes. There is lesser incidence of redetachment with incomplete tamponade in OCT.

    17. Detection of E.Coli Strains Containing Shiga Toxin (Stx1/2 Gene in Diarrheal Specimens from Children Less than 5 Years Old by PCR Technique and Study of the Patterns of Antibiotic Resistance

      Directory of Open Access Journals (Sweden)

      MR Pourmand

      2009-10-01

      Full Text Available Introduction: Shiga toxin- producing Escherichia coli (STEC is an emerging bacterial pathogen in developing countries that causes several diseases such as diarrhea, hemorrhagic colitis (HC and hemolytic uremic syndrome (HUS, particularly in children. Aim of the research was detection of STEC in diarrheal specimens from under 5 year olds and study of the patterns of antibiotic resistance of these strains. Methods: In the study,300 fecal samples were collected from children with diarrhea referring to Ali Asghar Hospital. E.coli species were isolated by standard bacteriological and biochemical tests. Presence of shiga toxin genes (stx1/2 was investigated by PCR technique (Qiagen. Antibiogram test for strains containing the toxin gene was performed using 16 different antibiotic discs (MAST by disc diffusion agar (Kirby-Bauer method. Results: From 39 E.coli isolates, 9(23.1% strains were detected by PCR to contain stx1/2 gene. One strain was resistant to all 16 antibiotics. All the STEC strains were sensitive to meropenem (MRP, imipenem (IMI, gentamycin (GEN and nitrofurantoin (NI. 4(44.44% strains showed multi-drug resistant pattern. All these 4strains were resistant to cotrimoxazole(SxT. Also, 6(66.66% strains were resistant to at least one antibiotic. Conclusion: In Iran, shiga toxin- producing Escherichia coli (STEC may be a commonly bacterial pathogen causing diarrhea, particularly in children. Therefore, we should use new techniques for investigation of these strains. Increase in number of emerging and new strains that could be resistant to classic antibiotics such as cotrimoxazole may be foreseen. It is suggested that antibiotics prescription programs in treatment of diarrhea causing E.coli strains be updated.

    18. Internally Mounting Strain Gages

      Science.gov (United States)

      Jett, J. R., Jr.

      1984-01-01

      Technique for mounting strain gages inside bolt or cylinder simultaneously inserts gage, attached dowel segment, and length of expandable tubing. Expandable tubing holds gage in place while adhesive cures, assuring even distribution of pressure on gage and area gaged.

    19. Running Title: Strained Yoghurts

      African Journals Online (AJOL)

      USER

      2012-09-27

      Sep 27, 2012 ... ever, the traditional method of producing strained yoghurt ... Food market studies have the essential function of providing ..... Communication No: 2001/21. ... fermented foods and beverages of Turkey. Crit. Rev. Food. Sci. Nutr.

    20. Flexible piezotronic strain sensor.

      Science.gov (United States)

      Zhou, Jun; Gu, Yudong; Fei, Peng; Mai, Wenjie; Gao, Yifan; Yang, Rusen; Bao, Gang; Wang, Zhong Lin

      2008-09-01

      Strain sensors based on individual ZnO piezoelectric fine-wires (PFWs; nanowires, microwires) have been fabricated by a simple, reliable, and cost-effective technique. The electromechanical sensor device consists of a single electrically connected PFW that is placed on the outer surface of a flexible polystyrene (PS) substrate and bonded at its two ends. The entire device is fully packaged by a polydimethylsiloxane (PDMS) thin layer. The PFW has Schottky contacts at its two ends but with distinctly different barrier heights. The I- V characteristic is highly sensitive to strain mainly due to the change in Schottky barrier height (SBH), which scales linear with strain. The change in SBH is suggested owing to the strain induced band structure change and piezoelectric effect. The experimental data can be well-described by the thermionic emission-diffusion model. A gauge factor of as high as 1250 has been demonstrated, which is 25% higher than the best gauge factor demonstrated for carbon nanotubes. The strain sensor developed here has applications in strain and stress measurements in cell biology, biomedical sciences, MEMS devices, structure monitoring, and more.

    1. Pathogenicity of local Metarhizium anisopliae var. acridum strains ...

      African Journals Online (AJOL)

      Locusts and grasshoppers are the most important economical threat in the sahelian agricultural system. Principal control strategies of these pests are synthetic chemicals which are, however, harmful to the environment and human health. Metarhizium anisopliae based biopesticide Green Muscle IMI330189 has been ...

    2. Supplier Selection within the Process of Analytical Hierarchy in a Business Bir Üretim İşletmesinde Analitik Hiyerarşi Süreci İle Tedarikçi Seçimi

      Directory of Open Access Journals (Sweden)

      Kezban KAPAR

      2013-09-01

      Full Text Available Supplier selection is one of the most critical activities in today's competitive businessworld. Selecting the supplier is a very difficult task to carry out. For determining the bestsupplier selection while assessing all the cases to choose the best approach, the AnalyticalHierarchy Process (AHP is used.AHP is a method used for systematic comparison, evaluation and selection of theoptions via determining the strengths and weaknesses of options. In this study, AHP methodwas utilized in the supplier selection and Expert Choice 11.5 was used while utilizing AHPmethod. The suppliers' superiorities were determined by Expert Choice and they werecompared systematically.Tedarikçi seçimi, günümüz rekabetçi iş dünyasında en kritik faaliyetlerden biridir. Birtedarikçi seçiminde en iyi olanı seçmek zor bir iştir. En iyi tedarikçi seçiminin belirlenmesiiçin çok amaçlı karar verme tekniklerinden birisi olan ve alternatif tedarikçilerdeğerlendirilerek bütün durumlar içinden en iyi olanı seçebilen Analitik Hiyerarşi Süreci(AHS, tedarikçi seçiminde yaygın olarak kullanılan bir yöntemdir.AHS, seçim aşamasında seçeneklerin üstünlüklerinin belirlenmesi ve sistematik olarakkarşılaştırılıp değerlendirilmesini sağlayan bir yöntemdir. Bu çalışmada, bir işletmenintedarikçi seçiminde AHS yönteminden yararlanılmış ve AHS yönteminin kullanılmasındaExpert Choice 11.5 programı kullanılmıştır. Expert Choice ile tedarikçilerin üstünlükleribelirlenmiştir ve sistematik olarak karşılaştırılmıştır.

    3. Five-class height-weight mean and SD system applying Estonian reference values of height-weight mean and SD for systematization of seventeen-year-old conscripts' anthropometric data.

      Science.gov (United States)

      Lintsi, Mart; Kaarma, Helje; Aunapuu, Marina; Arend, Andres

      2007-03-01

      A study of 739 conscripts aged 17 years from the town of Tartu and from the Tartu county was performed. Height, weight, 33 anthropometric measurements and 12 skinfolds were measured. The data were classified into five height-weight mean and SD-classes applying the Estonian reference values for this age and sex (Grünberg et al. 1998). There were 3 classes with conformity between height and weight class: 1--small (small height and small weight), 2--medium (medium height and medium weight), 3--large (large height and large weight), 4--weight class dominating (pyknomorphic) and 5--height class dominating (leptomorphic). It was found, that in classes 1, 2 and 3 the height and weight increase was in accordance with the increase in all heights, breadths and depths, circumferences, skinfolds, body fat, muscle and bone mass. In class 4 circumferences, skinfolds, body fat and muscle mass were bigger. In class 5 all heights and the relative bone mass were bigger. The present investigation confirms the assumption that the five height-weight mean and SD five-class system applying the Estonian reference values for classifying the anthropometric variables is suitable for seventeen-year-old conscripts. As well the border values of 5%, 50% and 95% for every anthropometrical variable in the five-classes were calculated, which may be helpful for practical classifying.

    4. Correlation between SD-OCT, immunocytochemistry and functional findings in a pigmented animal model of retinal degeneration

      Directory of Open Access Journals (Sweden)

      Nicolás eCuenca

      2014-12-01

      Full Text Available Purpose: The P23H rhodopsin mutation is an autosomal dominant cause of retinitis pigmentosa. The degeneration can be tracked using different anatomical and functional methods. In our case, we evaluated the anatomical changes using Spectral-Domain Optical Coherence Tomography (SD-OCT and correlated the findings with retinal thickness values determined by immunocytochemistry.Methods: Pigmented rats heterozygous for the P23H mutation, with ages between P18 and P180 were studied. Function was assessed by means of optomotor testing and ERGs. Retinal thicknesses measurements, autofluorescence and fluorescein angiography were performed using Spectralis OCT. Retinas were studied by means of immunohistochemistry. Results: Between P30 and P180, visual acuity decreased from 0.500 to 0.182 cycles per degree (cyc/deg and contrast sensitivity decreased from 54.56 to 2.98 for a spatial frequency of 0.089 cyc/deg. Only cone-driven b-wave responses reached developmental maturity. Flicker fusions were also comparable at P29 (42 Hz. Double flash-isolated rod-driven responses were already affected at P29. Photopic responses revealed deterioration after P29.A reduction in retinal thicknesses and morphological modifications were seen in OCT sections. Statistically significant differences were found in all evaluated thicknesses. Autofluorescence was seen in P23H rats as sparse dots. Immunocytochemistry showed a progressive decrease in the outer nuclear layer, and morphological changes. Although anatomical thickness measures were significantly lower than OCT values, there was a very strong correlation between the values measured by both techniques.Conclusions: In pigmented P23H rats, a progressive deterioration occurs in both retinal function and anatomy. Anatomical changes can be effectively evaluated using SD-OCT and immunocytochemistry, with a good correlation between their values, thus making SD-OCT an important tool for research in retinal degeneration.

    5. The NPOESS Preparatory Project Science Data Segment (SDS) Data Depository and Distribution Element (SD3E) System Architecture

      Science.gov (United States)

      Ho, Evelyn L.; Schweiss, Robert J.

      2008-01-01

      The National Polar-orbiting Operational Environmental Satellite System (NPOESS) Preparatory Project (NPP) Science Data Segment (SDS) will make daily data requests for approximately six terabytes of NPP science products for each of its six environmental assessment elements from the operational data providers. As a result, issues associated with duplicate data requests, data transfers of large volumes of diverse products, and data transfer failures raised concerns with respect to the network traffic and bandwidth consumption. The NPP SDS Data Depository and Distribution Element (SD3E) was developed to provide a mechanism for efficient data exchange, alleviate duplicate network traffic, and reduce operational costs.

    6. Large Eddy Simulation of an SD7003 Airfoil: Effects of Reynolds number and Subgrid-scale modeling

      DEFF Research Database (Denmark)

      Sarlak Chivaee, Hamid

      2017-01-01

      This paper presents results of a series of numerical simulations in order to study aerodynamic characteristics of the low Reynolds number Selig-Donovan airfoil, SD7003. Large Eddy Simulation (LES) technique is used for all computations at chord-based Reynolds numbers 10,000, 24,000 and 60...... the Reynolds number, and the effect is visible even at a relatively low chord-Reynolds number of 60,000. Among the tested models, the dynamic Smagorinsky gives the poorest predictions of the flow, with overprediction of lift and a larger separation on airfoils suction side. Among various models, the implicit...

    7. Beyond Retinal Layers: A Deep Voting Model for Automated Geographic Atrophy Segmentation in SD-OCT Images.

      Science.gov (United States)

      Ji, Zexuan; Chen, Qiang; Niu, Sijie; Leng, Theodore; Rubin, Daniel L

      2018-01-01

      To automatically and accurately segment geographic atrophy (GA) in spectral-domain optical coherence tomography (SD-OCT) images by constructing a voting system with deep neural networks without the use of retinal layer segmentation. An automatic GA segmentation method for SD-OCT images based on the deep network was constructed. The structure of the deep network was composed of five layers, including one input layer, three hidden layers, and one output layer. During the training phase, the labeled A-scans with 1024 features were directly fed into the network as the input layer to obtain the deep representations. Then a soft-max classifier was trained to determine the label of each individual pixel. Finally, a voting decision strategy was used to refine the segmentation results among 10 trained models. Two image data sets with GA were used to evaluate the model. For the first dataset, our algorithm obtained a mean overlap ratio (OR) 86.94% ± 8.75%, absolute area difference (AAD) 11.49% ± 11.50%, and correlation coefficients (CC) 0.9857; for the second dataset, the mean OR, AAD, and CC of the proposed method were 81.66% ± 10.93%, 8.30% ± 9.09%, and 0.9952, respectively. The proposed algorithm was capable of improving over 5% and 10% segmentation accuracy, respectively, when compared with several state-of-the-art algorithms on two data sets. Without retinal layer segmentation, the proposed algorithm could produce higher segmentation accuracy and was more stable when compared with state-of-the-art methods that relied on retinal layer segmentation results. Our model may provide reliable GA segmentations from SD-OCT images and be useful in the clinical diagnosis of advanced nonexudative AMD. Based on the deep neural networks, this study presents an accurate GA segmentation method for SD-OCT images without using any retinal layer segmentation results, and may contribute to improved understanding of advanced nonexudative AMD.

    8. PENGEMBANGAN RPP DAN LKPD BERBASIS REALISTIC MATHEMATICS EDUCATION DENGAN MEMERHATIKAN BEBAN KOGNITIF SISWA MATERI BANGUN RUANG SEDERHANA KELAS IV SD

      Directory of Open Access Journals (Sweden)

      Eko Waluyo

      2016-12-01

      Dalam suatu pembelajaran, dengan melibatkan siswa dalam menemukan suatu konsep materi matematika, siswa akan lebih mudah untuk memahami materi. Materi matematika dalam dipelajari dengan melibatkan obyek dunia nyata siswa sekolah dasar dengan memerhatikan beban kognitif siswa. Melalui bimbingan guru, siswa akan lebih mudah dalam menemukan konsep. Dalam tulisan ini dibahas pengembangan RPP dan LKPD berbasis Realistic Mathematics Education dengan memerhatikan beban kognitif siswa materi bangun ruang sederhana kelas IV SD. Model pengembangan yang digunakan model Plomp dengan lima fase. Hasil pengembangan RPP dan LKPD ini valid, praktis, dan efektif.

    9. The achievement of market study on a representative sample of companies in Romania about SD and CSR communication

      Directory of Open Access Journals (Sweden)

      Mihaela Bucur

      2014-05-01

      Full Text Available The purpose of this paper is to provide some results on how firms in Romania made communication on Corporate Social Responsibility (CSR and sustainable development (SD. The paper identifies the real pulse of Romanian business on the premise of communication responsible. Our approach shows how communication is performed inside and outside the company, the issues of CSR in the world customers, suppliers, business partners and customers. The findings demonstrate where are communication problems which components are satisfied through communication and where there should be improvements.

    10. PdS and SdP Receiver Functions Image of the Lithosphere underneath the Southern African Regions

      DEFF Research Database (Denmark)

      Soliman, Mohammad Youssof Ahmad; Thybo, Hans; Levander, A

      2009-01-01

      to 350 km depth by Jordan (1975), has to be revealed in more detail, and a better understanding should yield new insight into the origin of Earth’s early continents. We have reassessed the data from the Kaapvaal seismic experiment for lithosphere structure by application of PdS receiver functions...... these preliminary results, we are continuing the experiments by calculation of theoretical receiver functions for a range of models, and are assessing the combined integrated PdS and SdP receiver function response in combination with teleseismic tomography to provide an integrated high resolution model....

    11. Phylogenetic features of hemagglutin gene in canine distemper virus strains from different genetic lineages.

      Science.gov (United States)

      Liao, Peng; Guo, Li; Wen, Yongjun; Yang, Yangling; Cheng, Shipeng

      2015-01-01

      In the present study, the genotype of two Canine distemper virus (CDV) strains, namely, ZJJ-SD and ZJJ-LN, were investigated, based on the whole hemagglutinin (HA) gene. The CDV strains were obtained from two foxes in Shandong Province and Liaoning Province in 2011. Phylogenetic analyses were carried out for 260 CDV strains worldwide, and a statistical analysis was performed in the amino acid substitutions at positions 530 and 549 of the HA protein. Phylogenetic analyses revealed that the two strains, ZJJ-SD and ZJJ-LN, belonged to the CDV Asia I lineage. Site 530 of HA protein was found to be relatively conserved within CDV lineages in different host species by combining the genetic sequence data with the published data from 260 CDV strains worldwide. The data analysis showed a bias toward the predicted substitution Y549H for the non-dog strains in Asia I and Europe lineages. The ratio of site 549 genetic drift in the HA gene were significantly different between dogs and non-dogs in the two lineages. The strain ZJJ-SD, from wild canid, has an Y549H substitution. It is one of three Y549H substitution for wild canids in Asia I lineages. Site 530 of HA protein was not immediately relative to CDV genetic drift from dogs to non-dogs. Statistical analysis indicated that non-dog strains have a high probability to contain Y549H than dog strains in Asia I and Europe lineages. Thus, site 549 is considered important in genetic drift from dogs to non-dogs, at least in Asia I and Europe lineages.

    12. PROFESIONALISME GURU SD / MI

      OpenAIRE

      Nursalim Nursalim

      2017-01-01

      Abstrak: Guru harus memiliki empat kompetensi dasar yaitu; kompetensi pedagogik, kom­petensi kepribadian, kompetensi sosial dan kompetensi profesional. Kompetensi profesional guru Sekolah Dasar/Madrasah Ibtidaiyah yaitu: 1) Menguasai materi, struktur, konsep, dan pola pikir keilmuan yang mendukung mata pelajaran yang diampu, 2) menguasai standar kompetensi dan kompetensi dasar mata pelajaran/bidang pengembangan yang diampu, 3) mengembangkan materi membelajaran yang diampu secara kreatif, ...

    13. PROFESIONALISME GURU SD / MI

      Directory of Open Access Journals (Sweden)

      Nursalim Nursalim

      2017-12-01

      Teachers must have four basic competencies namely; pedagogical competence, personality com- petence, social competence and professional competence. Professional competence of teachers of Primary School / primary islamic school includes 1 Mastering the materials, structure, concept, and scientific mindset that support the subjects being taught, 2 mastering the competency standard and basic competency of the subjects being taught, 3 developing the material being taught creatively, 4 develop professionalism in sustainably by doing reflective actions, 5 utilizing information and communication technology to communicate and develop themselves. Teacher professionalism can be leveled. Efforts that can be done in improving teacher profesionalism are: 1 reading books about education, 2 reading and writing scientific papers, 3 following the actual news from news media, 4 joining training, 5 following Teacher Working Group, 6 conducting Classroom Action Research (CAR, and 6 participating actively in professional organizations.

    14. FLOODPLAIN, MEADE COUNTY, SD

      Data.gov (United States)

      Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

    15. HYDRAULICS, Sanborn COUNTY, SD

      Data.gov (United States)

      Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

    16. Vibrational relaxation dynamics of SD molecules in As2S3: Observation of an anomalous isotope effect

      International Nuclear Information System (INIS)

      Engholm, J.R.; Happek, U.; Rella, C.W.

      1995-01-01

      It is generally assumed that the vibrational relaxation of molecular impurities in crystals and glasses mainly depends on the order of the decay process, with lower order processes leading to more rapid relaxation (a behavior that is known under the term open-quotes gap-lawclose quotes). Here we present measurements that contradict this assumption. Using high intensity psec pulses of the Stanford FEL we measured the relaxation rate of the SD vibrational stretch mode (at a frequency of 1800 cm) by applying a pump-probe technique. We find relaxation rates on the order of 2x10 9 sec -1 , which are a factor of 2 lower than those found for the isotope molecule SH (at a frequency of about 2500 cm - 1 ) in the same host 1 . We recall that the relaxation of the SD vibrational stretch mode is controlled by a lower order process as compared to the SH molecule, which is due to the smaller number of host vibrational quanta to match the energy of the stretch mode; a fact we have confirmed experimentally by temperature dependent relaxation measurements. Thus our remits are in marked contrast to the so-called open-quotes Gap-Lawclose quotes and emphasize the importance of the molecule - host coupling in the relaxation dynamics

    17. A Single Recessive Mutated Gene (Sd237-1) Controlling Semi-Dwarf Plant Stature of Rice

      International Nuclear Information System (INIS)

      Sobrizal

      2009-01-01

      Dwarfism is a valuable trait in crop breeding, because it increases lodging resistance and decreases damages due to wind and rain. During the course of this study, a semi-dwarf mutant was successfully induced through 200 Gy gamma ray irradiated KI 237 seeds. KI 237 is a pure line with high yield potency, developed through an Indica-Japonica cross of IR36 / Koshihikari. The selected semi-dwarf plant reached 60 - 62 % of plant height of original plant KI 237 at the mature stage. The length of inter nodes, panicle, and seed were also compared between these two plants. The retardation of the 1 st (uppermost) inter nodes was 24 %, moreover, the retardation of panicle and seed length were only 10 % and 2 %, respectively. The elongation pattern of the inter nodes in this mutant was almost the same as sd1 (Dee-geo-woo-gen), the original parent of the first release modern rice variety, but their performances were different. Based on the segregation analysis in M 2 and M 3 generation it was concluded that this mutant was controlled by a single recessive mutated gene. This gene was designated as sd 237-1 . This mutant should be useful as a genetic resource for the improvement of KI 237 line through back-cross breeding as well as be developed further in breeding program directly to be a new high yielding mutant variety. (author)

    18. Peningkatan Karakter Mahasiswa Program Studi PGSD pada Mata Kuliah Pengembangan Pembelajaran IPA SD di Universitas Muhammadiyah Sidoarjo

      Directory of Open Access Journals (Sweden)

      Enik Setiyawati

      2017-05-01

      Full Text Available PGSD student's character can be seen from various aspects of the attitude that must be owned by an educator, especially educators in primary school. Some of these aspects are honesty, cooperation, discipline, responsibility, and independence. Aspects of honesty student still low category, the aspect of cooperation, discipline, responsibility, and independence are being categorized. The purpose of this research is to describe the increase in student character study program PGSD On Learning Course Development IPA SD At the University of Muhammadiyah Sidoarjo. In conducting the study, researchers used a classroom action research (Classroom Action Research. Based on the results of the study in the first cycle and the second cycle, it can be seen that there is a rise in the value of the character of students in primary school teaching courses Learning Development IPA SD from the first cycle to the second cycle. Value of character in the first cycle of 71.4, while the value of the character in the second cycle of 98.5. This shows that there is an increase of 27.1 of all indicators of character shown by students of primary school teaching course on development of Elementary Science Lesson.

    19. PENANAMAN KESADARAN DAN TANGGUNGJAWAB TERHADAP LINGKUNGAN HIDUP MELALUI GREEN SCHOOL DI SD NEGERI DEMAKAN 02 TAHUN PELAJARAN 2014/2015

      Directory of Open Access Journals (Sweden)

      Pranichayudha Rohsulina

      2015-09-01

      Full Text Available Abstract This devotion aims to instill awareness and responsibility towards the environment in elementary school students. This activity was conducted in 02 primary schools with class participants Demakan 3, 4, and 5 in groups. Service activities is carried out through four stages, includes the extension (socialization, implementation, monitoring, and evaluation of results. Results devotion shows that primary school Demakan 02 Sukoharjo related to green school in the school can be taken several conclusions are: 1 There is the awareness and responsibility of environmental awareness green in SD N Demakan 02 Sukoharjo. 2 Farming with students of all ages to encourage their interest in nature and enthusiasm early in life. 3 This devotion succeeded yield as much as 110 pot polybag. Keywords: green school, awareness, responsibility Abstract This devotion aims to instill awareness and responsibility towards the environment in elementary school students. This activity was conducted in 02 primary schools with class participants Demakan 3, 4, and 5 in groups. Service activities is carried out through four stages, includes the extension (socialization, implementation, monitoring, and evaluation of results. Results devotion shows that primary school Demakan 02 Sukoharjo related to green school in the school can be taken several conclusions are: 1 There is the awareness and responsibility of environmental awareness green in SD N Demakan 02 Sukoharjo. 2 Farming with students of all ages to encourage their interest in nature and enthusiasm early in life. 3 This devotion succeeded yield as much as 110 pot polybag. Keywords: green school, awareness, responsibility

    20. Pengembangan Subject Specific Pedagogy (SSP Tematik Berbasis Local Wisdom Untuk Membangun Karakter Hormat dan Kepedulian Siswa SD

      Directory of Open Access Journals (Sweden)

      Amaliyah Ulfah

      2018-01-01

      Full Text Available This study aims at generating possible thematic Subject Specific Pedagogy (SSP based on local wisdom and examining the results teachers and students perception on the pedagogical approach developed in the preliminary field testing. Drawing upon the notion of research and development by Borg & Gall, this research was conducted through different stages involving information gathering, planning, developing preliminary product, preliminary field testing, and revising. The subjects were a small group of second grade students of SD Muhammadiyah Bodon and SD Muhammadiyah Sidoarum Yogyakarta. Each consists of 10 students. The data gathering instrument consists of product validation, character observation sheets, and teacher assessment sheets. The data gathering instrument consists of product validation tool, character observation sheets, and teachers’ assessment sheets. The SSP product generated in this study consists of lesson plans, teaching materials, worksheets, and expert perception. According to the experts of media, materials, and evaluation, the SSP product is in good categories. First grade teachers result a good score to the syllabus and lesson plans, while the worksheets and evaluation are in very good category. The results from the students responses to the textbooks is 78, which is in very good category, while the students worksheets score 71 which includes in excellent category. Therefore, the developed thematic SSP based on local wisdom can be declared appropriate for use in learning.

    1. The NPOESS Preparatory Project (NPP) Science Data Segment (SDS) Data Depository and Distribution Element (SD3E) System Architecture

      Science.gov (United States)

      Ho, Evelyn L.; Schweiss, Robert J.

      2008-01-01

      The National Polar-orbiting Operational Environmental Satellite System (NPOESS), the U.S. Government's future low-Earth orbiting satellite system, will monitor global weather and environmental conditions. Serving as a risk reduction for NPOESS, the NPOESS Preparatory Project (NPP) will provide remotely sensed atmospheric, land, ocean, ozone, and sounder data that will serve the meteorological and global climate change scientific communities. The National Aeronautics and Space Administration (NASA) NPP Science Data Segment's (SDS) primary role is to independently assess the quality of the NPP science and environmental data records for their ability to support climate research. The SDS is composed of nine elements; an input element that receives data from the operational agencies and acts as a buffer, a calibration analysis element, five elements devoted to measurement based quality assessment, an element used to test algorithmic improvements, and an element that provides overall science direction. Each element requires a set of sensor specific science data products for their evaluation. There are four NPP sensors that will be flown on the NPP observatory. They are the Visible Infrared Imagining Radiometer Suite (VIIRS), the Advanced Technology Microwave Sounder (ATMS), the Cross-Track Infrared Sounder (CrIS), and the Ozone Mapper/Profiler Suite (OMPS). It is estimated that these four sensors combined will make daily data requests for approximately six terabytes of NPP science products from the operational data providers. As a result, issues associated with duplicate data requests, data transfers of large volumes of diverse products, and data transfer failures raised concerns with respect to the network traffic and bandwidth consumption. Therefore, a central data broker system for receiving and buffering data requests and data products for the SDS was developed. The data element for this system is called the SDS Data Depository and Distribution Element (SD3E). It

    2. Order-Order Transition of C → sdG → sL → S in ABC Triblock Copolymer Thin Film Induced by Solvent Vapor.

      Science.gov (United States)

      Luo, Chunxia; Huang, Weihuan; Han, Yanchun

      2009-04-01

      The morphology transition of polystyrene-block-poly(butadiene)-block-poly(2-vinylpyridine) (SBV) triblock thin film induced in benzene vapor showing weak selectivity for PS is investigated. The order-order transitions (OOT) in the sequence of core-shell cylinders (C), sphere in 'diblock gyroid' (sdG), sphere in lamella (sL) and sphere (S) are observed. The projection along (111) direction in Gyroid phase (sdG(111)) is found to epitaxially grow from C(001) in the film. Instead of sdG(111), sdG(110)(0.1875) develops to the phase of sL. Consequently, the film experiences the transition sequence of sdG(111) → sdG(211) → sdG(110)(0.25)  → sdG(110)(0.1875) between C and sL. The mechanism is analyzed from the total surface area of the blocks. Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

    3. Halofuginone ameliorates inflammation in severe acute hepatitis B virus (HBV-infected SD rats through AMPK activation

      Directory of Open Access Journals (Sweden)

      Zhan WL

      2017-10-01

      Full Text Available Weili Zhan, Yanhong Kang, Ning Chen, Chongshan Mao, Yi Kang, Jia Shang Department of Infectious Diseases, Henan Provincial People’s Hospital, Zhengzhou, Henan, China Abstract: The hepatitis B virus (HBV has caused acute and chronic liver diseases in ~350 million infected people worldwide. Halofuginone (HF is a plant alkaloid which has been demonstrated to play a crucial role in immune regulation. Our present study explored the function of HF in the immune response of HBV-infected Sprague Dawley (SD rats. Plasmid containing pCDNA3.1-HBV1.3 was injected in SD rats for the construction of an acute HBV-infected animal model. Our data showed that HF reduced the high concentrations of serum hepatitis B e-antigen, hepatitis B surface antigen, and HBV DNA induced by HBV infection. HF also reduced the number of T helper (Th17 cells and the expression of interleukin (IL-17 compared with the pCDNA3.1-HBV1.3 group. Moreover, pro-inflammatory cytokine levels (IL-17, IL-23, interferon-γ, and IL-2 were downregulated and anti-inflammatory cytokine levels (IL-4 and IL-13 were upregulated by HF. Through further research we found that the expression of AMP-activated protein kinase (AMPK and IKBA which suppressed NF-κB activation was increased while the expression of p-NF-κB P65 was decreased in pCDNA3.1-HBV1.3+HF group compared with pCDNA3.1-HBV1.3 group, indicating that HF may work through the activation of AMPK. Finally, our conjecture was further verified by using the AMPK inhibitor compound C, which counteracted the anti-inflammation effect of HF, resulting in the decreased expression of AMPK, IKBA and increased expression of p-NF-κB P65 and reduced number of Th17 cells. In our present study, HF was considered as an anti-inflammatory factor in acute HBV-infected SD rats and worked through AMPK-mediated NF-κB p65 inactivation. This study implicated HF as a potential therapeutic strategy for hepatitis B. Keywords: halofuginone, hepatitis B virus

    4. PENGEMBANGAN RPP TEMATIK-INTEGRATIF UNTUK MENINGKATKAN KARAKTER KERJA KERAS DI KELAS 1 SD N 2 SOKARAJA TENGAH

      Directory of Open Access Journals (Sweden)

      Sri Muryaningsih

      2015-07-01

      Full Text Available Penelitian ini bertujuan untuk menghasilkan RPP tematik-integratif dalam peningkatan karakter kerja keras dan mengetahui efektifitas penerapan RPP tematik-integratif dalam peningkatan karakter kerja keras bagi peserta didik kelas 1 SD N 2 Sokaraja Tengah. Penelitian ini menggunakan langkah pengembangan menurut Borg and Gall.Hasil penelitian menunjukkan bahwa produk yang dikembangkan dalam penelitian ini layak digunakan sesuai hasil penilaian ahli teknologi pembelajarann dan ahli media pembelajaran terhadap produk yang dikembangkan dengan kriteria “sangat baik” dengan bukti perolehan skor total validasi sebesar 39 dan 38. Produk yang dikembangkan juga efektif diterapkan sesuai dengan hasil uji coba dilapangan. Keefektivan RPP hasil pengembangan dilihat dari hasil keterlaksanaan RPP adalah berkriteria “sangat baik” dengan bukti keterlaksanaan mencapai 100%. Kenaikan karakter kerja keras dari kriteria “cukup” menjadi kriteria “baik”. Ketuntasan hasil belajar kelas eksperimen mencapai 93,54% dan ketuntasan hasil belajar kelas kontrol mencapai 61,3%. Kata Kunci: RPP tematik-integratif, pendidikan karakter   DEVELOPING A THEMATIC-INTEGRATED LESSON PLAN TO INCREASE THE HARD-WORKING CHARACTER OF GRADE 1 STUDENTS OF SD N 2 SOKARAJA TENGAH Abstract This research is aimed to develop thematic-integrated lesson plan to increase hard-working character and to know the effectiveness of the thematic-integrated lesson plan in the increase of hard-workig character of grade 1 students of SD N 2 Sokaraja Tengah. This research is a research and development study from Borg & Gall model. The result shows that the product developed in this research is suitable to use.  The result of teaching technology and learning media expert analysis on this product shows that it is ”very good”, as proved by the validation total scores of 39 and 38 out of 45. This product is also effective to apply as shown the result of field testing of the lesson plan. The

    5. Strains and Sprains

      Science.gov (United States)

      ... lot of pressure on a muscle or you push it too far, such as when lifting a heavy object. Strains may be more likely to happen if you haven't warmed up first to get blood circulating to the muscles. They're also common for someone returning to a sport after the off-season. That first time playing ...

    6. Transportation Structure Analysis Using SD-MOP in World Modern Garden City: A Case Study in China

      Directory of Open Access Journals (Sweden)

      Jiuping Xu

      2012-01-01

      Full Text Available The idea of the “garden city” was developed theoretically to offer solutions to serious city development problems such as traffic congestion, population, and environmental pollution, among which the transportation is considered the most important. The question is how to develop balanced transportation in a garden city. Transportation is a complex system, particularly in a garden city. Therefore, we establish a new approach named the transportation multiobjective optimization system dynamics  (SD-MOP model, which firstly calculates the optimal proportion of different transport means with an MOP approach and then applies them to the dynamic transportation system to analyze the results and analyze the influence on the whole system using different transportation means variation. In this paper, we take Chengdu as an example, one of the few cities in the world declared as building a garden city, and then develop some recommendations about world modern garden city transportation system development.

    7. Riwayat gizi buruk masa lalu (stunted tidak berhubungan dengan prestasi belajar siswa SD di Kabupaten Sikka Nusa Tenggara Timur

      Directory of Open Access Journals (Sweden)

      Tobianus Hasan

      2016-08-01

      terutama balita berisiko tinggi mengalami masalah kesehatan dan gizi dengan persentase 43,3 pada tahun 2009 dan 42,3 pada tahun 2010. Persentase kelulusan siswa SD di Kecamatan Mego pada tahun ajaran 2009/2010 menempati urutan ke-15 dari 21 kecamatan yang ada di Kabupaten Sikka.Tujuan: Untuk mengetahui hubungan antara status gizi masa lalu (stunted dan prestasi belajar siswa SD Kecamatan Mego, di Kabupaten Sikka NTT.Metode: Jenis penelitian ini adalah observasional dengan rancangan penelitian cross sectional study dengan sample penelitian meliputi anak sekolah dasar (SD kelas III yang memenuhi kriteria inklusi dan eksklusi.Hasil: Hasil penelitian menunjukan bahwa secara bivariat kondisi stunted mempengaruhi prestasi belajar (p=0,027, selain stunted, faktor luar yang mempengaruhi prestasi belajar adalah pendidikan ibu (p=0,001, pendidikan ayah (p=0,001 dan intelegensi anak (p=0,027 Secara multivariat yang paling mempengaruhi prestasi belajar siswa SD di Kecamatan Mego adalah pendidikan ayah dan ibu. Tetapi faktor yang paling dominan mempengaruhi prestasi belajar siswa SD hanya pendidikan ibu (p=0,001.Kesimpulan: Sebagian besar siswa yang menderita stunted memiliki prestasi belajar yang rendah (87,2% dan stunted tidak memiliki hubungan yang signifikan dengan prestasi belajar. Prestasi belajar siswa dipengaruhi oleh pendidikan orang tua.KATA KUNCI: stunted, prestasi belajar

    8. Alpha-cluster transfer process in colliding S-D shell nuclei using the energy density formalism

      International Nuclear Information System (INIS)

      Puri, R.K.; Gupta, R.K.

      1992-01-01

      The energy density formalism is used for the first time to study the resonance-like behaviour of the α-cluster transfer process, observed for collisions between the s-d shell nuclei. Within the dynamical fragmentation theory, this formalism is shown to give better the observed alpha resonance-like mass spectrum of colliding α-particle nuclei and its suppression on adding neutrons to either of the α-particle reaction partners, compared with the earlier calculations of one of us and collaborators using the proximity pocket formula. For composite systems with N>>Z, these calculations predict an explicit preference for transfer of those clusters that are observed in recent cluster radioactivity. (Author)

    9. Research on Scenic Spot’s Sustainable Development Based on a SD Model: A Case Study of the Jiuzhai Valley

      Directory of Open Access Journals (Sweden)

      Zhixue Liao

      2014-07-01

      Full Text Available In the field of tourism, the development of tourist attractions is playing an increasingly crucial role in tourism economy, regional economy and national economy. However, the eco-environment has been damaged while tourism industry develops rapidly. Thus, to solve the contradiction between tourism development and eco-environment protection is the key to achieving sustainable development of tourism. This paper builds a SD model, which is based on the analysis of the economic subsystem and environment subsystem, to promote sustainable development. In order to show the effectiveness of the model, Jiuzhai Valley is taken as the research object and a decisive basis is provided for the path adjustment of sustainable development in tourist scenic.

    10. Applied reliability assessment for the passive safety systems of nuclear power plants (NPPs) using system dynamics (SD)

      International Nuclear Information System (INIS)

      Kim, Yun Il; Woo, Tae Ho

      2018-01-01

      The passive system by the free-fall is investigated in the accident of nuclear power plants (NPPs). The complex algorithm of the system dynamics (SD) modeling is done in the passive cooling system. The nuclear passive system by free-fall is successfully modeled for the loss of coolant accident (LOCA). Conventional passive system of gravity or natural circulation is working only when the piping systems is in the good condition. The external coolant supply system is introduced in the case of the piping system failure. The water is poured into the reactor through the guiding piping or tube. If the explosion happens, the coolants could be showering into the reactor core and its building. New kind of passive system is expected successfully in the on-site black out where the drone could be operated by battery or engine.

    11. Safety assessment for electricity generation failure accident of gas cooled nuclear power plant using system dynamics (SD) method

      Energy Technology Data Exchange (ETDEWEB)

      Woo, Tae Ho [Seoul National Univ. (Korea, Republic of). Dept. of Nuclear Engineering

      2013-04-15

      The power production failure happens in the loss of coolant of the nuclear power plants (NPPs). The air ingress is a serious accident in gas cooled NPPs. The quantification of the study performed by the system dynamics (SD) method which is processed by the feedback algorithms. The Vensim software package is used for the simulation, which is performed by the Monte-Carlo method. Two kinds of considerations as the economic and safety properties are important in NPPs. The result shows the stability of the operation when the power can be decided. The maximum value of risk is the 11.77 in 43rd and the minimum value is 0.0 in several years. So, the success of the circulation of coolant is simulated by the dynamical values. (orig.)

    12. Complex risk analysis for loss of electric power in liquid metal nuclear reactor by system dynamics (SD) method

      Energy Technology Data Exchange (ETDEWEB)

      Woo, Tae Ho [Seoul National Univ. (Korea, Republic of). Dept. of Nuclear Engineering

      2012-07-15

      The power stabilization of the nuclear power plants (NPPs) is investigated in the aspect of the liquid metal coolant. The quantification of the risk analysis is performed by the system dynamics (SD) method which is processed by the feedback and accumulation complex algorithms. The Vensim software package is used for the simulations, which is supported by the Monte-Carlo method. There are 2 kinds of considerations as the economic and safety properties. The result shows the stability of the operations when the power can be decided. This shows the higher efficiency of the reactor. The failure frequency is 16/60 = 27%. In the event of Power Stabilized, the failure event is in the quite lower frequency rate. The commercial use of the reactor is important in the operations. (orig.)

    13. Effect of radiation-induced heart injury on content of cardiac troponin I and endothelin-1 in SD rats

      International Nuclear Information System (INIS)

      Xu Jiuhong; Gao Yaoming; Zhang Junning; Li Xinli

      2011-01-01

      Objective: To investigate the effect of radiation-induced heart injury (RIHD) on cardiac endothelin-1 (ET-1) and cardiac troponin I (cTnI) in SD rats, and the possibility regarding ET-1 and cTnI as biomarker of RIHD was also explored. Methods: Healthy female SD rats were randomly divided into two groups: the control group (C) and irradiation group (R). The rats in R group were irradiated with linear accelerator at a single dose of 25 Gy. Five milliliters blood was collected from the inferior vena cava on the 5th, 15th, 30th, 60th day after radiation. Blood was centrifuged and serum was collected. Content of ET-1 and cTnI in blood serum were detected by ELISA kits. Results: The content of ET-1 in the R group was always higher than that in the C group (P<0.01) during the whole process, and the difference between two groups had statistical significance only on the 5th day (P<0.01) and 15th day (P<0.05) after radiation. However, the content of cTnI in R group was higher than that in the C group within 30 days after radiation, then decreased, and only on the 15th day (P<0.05) and the 30th day (P<0.01) after radiation, there was statistical difference between two groups. Conclusion: The content of ET-1 and cTnI in blood serum increase obviously after receiving RIHD, so these two indicators can be used as markers to diagnose early RIHD sensitively and specifically. (authors)

    14. Kebiasaan jajan dan pola makan serta hubungannya dengan status gizi anak usia sekolah di SD Sonosewu Bantul Yogyakarta

      Directory of Open Access Journals (Sweden)

      Kurnia Noviani

      2016-08-01

      Full Text Available ABSTRACTBackground: Elementary school children are in the developmental age, thus need nutritions with good and proper quality and quantity. Nutrient needs can be fulfilled through eating habits. Snacking habit can also contribute to nutritional status in children if the snack consumed has good quality in term of the typeand quantity.Objectives: To understand the relationship between snacking habit and diet with nutritional status of elementary school children in SD Sonosewu Bantul Yogyakarta.Methods: This study was an observational research with cross sectional approach. This study population was all students in SD Sonosewu Bantul Yogyakarta grades III, IV, V, that were 160 respondents. The sample used in this study was 65 people selected by using simple random sampling. The process ofselecting a random sample was based on the random number table. The research instruments used were questionnaires, form of 24 -hour food recall for 1 day, bathroom scales, and microtoise. The collected data was analyzed by using a statistical test chi-square.Results: Respondents who had frequent snacking habit with a normal nutritional status was 27 respondents (81%, whereas those who had less frequent snacking habit with wasting nutritional status was 7 respondents (21.9%. Respondents with a good diet (>80% RDA with wasting nutritional status was 9 respondents (75% and respondents who had bad diet with normal nutritional status was 34 respondents (66%. Chi-Square analysis in the relationship between snacking habit and nutritional status obtained 0.781 p value (p>0.05 which mean that there was no statistically significant of relationship between snacking habits and child’s nutritional status. Whereas Chi-Square analysis of diet and nutritional status showed a significant relationship with 0.008 p value (p<0.05 means that there was a relationship between diet and nutritional status.Conclusions: There was a relationship between diet and nutritional

    15. Geleneksel Bir Türk Et Ürünü Olan Akçaabat Köftesinin Kimyasal Bileşimi, Renk ve Tekstürel Özellikleri (İngilizce

      Directory of Open Access Journals (Sweden)

      Furkan Türker Sarıcaoğlu

      2015-02-01

      Full Text Available Bu çalışmada, Trabzon ve Samsun’daki işletmelerden alınan toplamda 30 adet Akçaabat köftesinin kimyasal bileşimi, renk ve tekstürel özellikleri belirlenmiştir. Samsun’daki işletmelerden alınan köfte örneklerinde ortalama değerler olarak %48.35 nem, %14.14 protein, %22.27 yağ ve %1.51 tuz belirlenirken, Trabzon’daki işletmelerden alınan örneklerde %54.53 nem, %15.17 protein, %19.09 yağ ve %1.23 tuz belirlenmiştir. Köfte örneklerinde doymamış yağ asitlerinden en yüksek miktarda palmitik ve stearik asit, tekli doymamış yağ asitlerinden ise oleik asit saptanmıştır. Köfte örneklerinin P/S oranları önerilen değerden daha düşük olurken, n-6/n-3 oranları yüksek olmuştur. Köftelerin L değerleri 39.10 ile 45.65 arasında değişmiş ve Samsun’daki işletmelerden alınan örneklerde daha yüksek bulunmuştur (P<0.05. L değerinin tersine, Trabzon’daki işletmelerden alınan köftelerin a değerleri, Samsun’daki işletmelerden alınanlardan daha yüksek bulunmuştur (P<0.05. Trabzon ve Samsun’daki işletmelerden alınan köfte örneklerinin ortalama sertlik ve çiğnenebilirlik değerleri sırasıyla 79.05 N-10.41 N.cm ve 142.46 N-17.17 N.cm olarak tespit edilmiş ve örneklerin sertlik ve çiğnenebilirlik değerleri arasında önemli farklılıklar belirlenmiştir (P<0.05. Bu sonuçlar Akçaabat köftesinin protein ve yağ açısından zengin bir kaynak olduğunu göstermektedir. Ancak, P/S ve n-6/n-3 oranlarının besin değeri üzerinde negatif bir etkisi vardır.

    16. Strains in general relativity

      International Nuclear Information System (INIS)

      Bini, Donato; Felice, Fernando de; Geralico, Andrea

      2006-01-01

      The definition of relative accelerations and strains among a set of comoving particles is studied in connection with the geometric properties of the frame adapted to a 'fiducial observer'. We find that a relativistically complete and correct definition of strains must take into account the transport law of the chosen spatial triad along the observer's congruence. We use special congruences of (accelerated) test particles in some familiar spacetimes to elucidate such a point. The celebrated idea of Szekeres' compass of inertia, arising when studying geodesic deviation among a set of free-falling particles, is here generalized to the case of accelerated particles. In doing so we have naturally contributed to the theory of relativistic gravity gradiometer. Moreover, our analysis was made in an observer-dependent form, a fact that would be very useful when thinking about general relativistic tests on space stations orbiting compact objects like black holes and also in other interesting gravitational situations

    17. Strain Induced Adatom Correlations

      OpenAIRE

      Kappus, Wolfgang

      2012-01-01

      A Born-Green-Yvon type model for adatom density correlations is combined with a model for adatom interactions mediated by the strain in elastic anisotropic substrates. The resulting nonlinear integral equation is solved numerically for coverages from zero to a limit given by stability constraints. W, Nb, Ta and Au surfaces are taken as examples to show the effects of different elastic anisotropy regions. Results of the calculation are shown by appropriate plots and discussed. A mapping to sup...

    18. Ratchetting strain prediction

      International Nuclear Information System (INIS)

      Noban, Mohammad; Jahed, Hamid

      2007-01-01

      A time-efficient method for predicting ratchetting strain is proposed. The ratchetting strain at any cycle is determined by finding the ratchetting rate at only a few cycles. This determination is done by first defining the trajectory of the origin of stress in the deviatoric stress space and then incorporating this moving origin into a cyclic plasticity model. It is shown that at the beginning of the loading, the starting point of this trajectory coincides with the initial stress origin and approaches the mean stress, displaying a power-law relationship with the number of loading cycles. The method of obtaining this trajectory from a standard uniaxial asymmetric cyclic loading is presented. Ratchetting rates are calculated with the help of this trajectory and through the use of a constitutive cyclic plasticity model which incorporates deviatoric stresses and back stresses that are measured with respect to this moving frame. The proposed model is used to predict the ratchetting strain of two types of steels under single- and multi-step loadings. Results obtained agree well with the available experimental measurements

    19. Identifikasi Carrier Bakteri Streptococcus β hemolyticus Group A pada Murid SD Negeri 13 Padang Berdasarkan Perbedaan Umur dan Jenis Kelamin

      Directory of Open Access Journals (Sweden)

      Fadhila Aini

      2016-01-01

      Full Text Available AbstrakStreptococcus β hemolyticus Grup A atau yang disebut juga Streptococcus pyogenes merupakan salah satu bakteri patogen yang banyak menginfeksi manusia.Bakteri ini dapat ditemukan sebagai carrier di saluran pernafasan terutama pada anak-anak, tidak menimbulkan penyakit tetapi berisiko untuk menyebarkan penyakit. Tujuan penelitian ini adalah menentukan jumlah carrier  bakteri Streptococcus β hemolyticus Grup A pada murid berdasarkan perbedaan umur dan jenis kelamin. Jenis penelitian ini adalah deskriptif cross-sectional dengan menggunakan sampel seluruh murid SD Negeri 13 Padang. Hasil penelitian adalah didapatkan 2 orang murid yang menderita carrier, yaitu pada kelompok usia>8-9 tahun dan >11 tahun. Berdasarkan jenis kelamin yang terdiri dari 54 orang laki-laki dan 50 orang perempuan, didapatkan 2 orang carrier yaitu hanya pada anak laki-laki. Hasil penelitian menunjukkan bahwa carrier bakteri Streptococcus β hemolyticus Group  A terdapat pada anak usia tersebut karena masih kurangnya pengetahuan tentang kebersihan. Carrier yang ditemukan hanya pada anak laki-laki kemungkinan disebabkan mereka lebih sering bermain di luar rumah dan terpapar dengan berbagai bakteri patogen dan kurang memperhatikan kebersihan diri.Kata kunci: carrier, streptococcus β hemolyticus grup A, umur, jenis kelamin AbstractGroup A Streptococcus β hemolyticus or also called Streptococcus pyogenes is one of many pathogenic bacteria that infect humans. These bacteria can be found as a carrier in the respiratory tract especially in children, do not cause disease but can be a risk for spreading the disease. This objective of this study was to determine the amount of the carrier of bacteria group A Streptococcus β hemolyticus based on age and gender differences. This research is a descriptive cross - sectional study using a sample of all students of SD Negeri 13 Padang. Based on the age of 104 students found that students who suffer 2 carrier, which is in the age

    20. Hubungan Status Sosial Ekonomi dan Gaya Hidup dengan Kejadian Obesitas pada Siswa SD Negeri 08 Alang Lawas Padang

      Directory of Open Access Journals (Sweden)

      Cici Octari

      2014-05-01

      Full Text Available AbstrakObesitas di Indonesia mulai menjadi masalah gizi masyarakat walaupun gizi kurang masih tinggi. Obesitas disebabkan oleh banyak faktor/multifaktorial yang dapat dibagi menjadi genetik dan lingkungan yang diantaranya adalah status sosial ekonomi dan gaya hidup. Penelitian ini menggunakan desain cross sectional study dengan populasi adalah seluruh siswa kelas I sampai V di SD N 08 Alang Lawas,Padang. Penelitian ini mendapatkan hasil 8,21% siswa mengalami obesitas, 11,79% overweight atau gemuk, 82,60% tingkat pendapatan orang tua siswa berada di atas garis kemiskinan, 71,30% ayah dan 71,80% ibu siswa memiliki tingkat pendidikan menengah, 58,50% siswa memiliki pola makan baik, dan 60% memiliki aktifitas fisik aktif. Tidak didapatkan hubungan yang bermakna antara kejadian obesitas dengan tingkat pendidikan orang tua (ayah: p=0,205 ; ibu: p=1,00, tingkat pendapatan orang tua (p=0,396, dan pola makan anak (p=0,245. Didapatkan hubungan yang bermakna antara aktifitas fisik anak dengan kejadian obesitas (p=0,048.Kata kunci: obesitas, anak, sosial-ekonomi, gaya hidupAbstractIn Indonesia, obesity has became a public nutrition problem although frequence of undernutrition was still high. The obesity caused by many factor/multifactorial that asssigned to genetic factor and environment factor. Two of the environment factors are social-economy and life style. Cross sectional study was chosen as a method to conduct the study. The study population were all the students on 1st grade to 5th grade in SD Negeri 08 Alang Lawas, Padang. The result shows that 8.21% of the students suffered from obesity, 11.79% were overweight, 82.60% of the students have the parents that have income more then the poverty line, 71.30% of the fathers and 71.80% of the mothers were middle graduations, 58.50% have good consumptions pattern, and 60% have active physical activity. There are no association between the obesity among the children with parent’s graduation (father: p=0

    1. Novel polymorphisms within the Dlk1-Dio3 imprinted locus in rat: a putative genetic basis for strain-specific allelic gene expression

      Directory of Open Access Journals (Sweden)

      Laura J Sittig

      2012-12-01

      Full Text Available The imprinted iodothyronine deiodinase-III (Dio3 thyroid hormone metabolizing gene exhibits paternal expression in most fetal tissues, yet exhibits aberrant, maternal expression in the hippocampus in F1 offspring of Sprague Dawley (SD x Brown Norway (BN rats. The maternal hippocampal expression is associated with lower Dio3 mRNA levels specifically in the hippocampus. Here, we tested the hypothesis that genetic polymorphisms between the SD and BN parent strains cause this aberrant allelic Dio3 expression and contribute to behavioral sequelae of higher thyroid hormone levels locally in the hippocampus, including anxiety-related behavior. We mapped and sequenced the Dio3 gene and several previously unmapped regions in the Dlk1-Dio3 locus that could regulate imprinting of the Dio3 gene. In the Dio3 promoter we identified four novel polymorphisms between the BN and SD strains. Next we took advantage of the fact that the Long Evans (LE strain exhibits identical polymorphisms as the SD strain in the region 5’ and including the Dio3 gene. By reciprocally crossing LE and BN strains we tested the relationship among Dio3 promoter region polymorphisms and Dio3 mRNA expression in the hippocampus. Aberrant strain-specific hippocampal Dio3 allelic expression replicated in the LE-BN reciprocal crosses, suggesting that hippocampal-specific imprinting of the Dio3 gene is not the result of a unique genetic or epigenetic characteristic of the SD rat strain, or a unique epistatic interaction between SD and BN. To our knowledge no other studies have reported a genetic x epigenetic interaction of genetic origin in the brain.

    2. Strain measurement based battery testing

      Science.gov (United States)

      Xu, Jeff Qiang; Steiber, Joe; Wall, Craig M.; Smith, Robert; Ng, Cheuk

      2017-05-23

      A method and system for strain-based estimation of the state of health of a battery, from an initial state to an aged state, is provided. A strain gauge is applied to the battery. A first strain measurement is performed on the battery, using the strain gauge, at a selected charge capacity of the battery and at the initial state of the battery. A second strain measurement is performed on the battery, using the strain gauge, at the selected charge capacity of the battery and at the aged state of the battery. The capacity degradation of the battery is estimated as the difference between the first and second strain measurements divided by the first strain measurement.

    3. Effects of footwear and stride length on metatarsal strains and failure in running.

      Science.gov (United States)

      Firminger, Colin R; Fung, Anita; Loundagin, Lindsay L; Edwards, W Brent

      2017-11-01

      The metatarsal bones of the foot are particularly susceptible to stress fracture owing to the high strains they experience during the stance phase of running. Shoe cushioning and stride length reduction represent two potential interventions to decrease metatarsal strain and thus stress fracture risk. Fourteen male recreational runners ran overground at a 5-km pace while motion capture and plantar pressure data were collected during four experimental conditions: traditional shoe at preferred and 90% preferred stride length, and minimalist shoe at preferred and 90% preferred stride length. Combined musculoskeletal - finite element modeling based on motion analysis and computed tomography data were used to quantify metatarsal strains and the probability of failure was determined using stress-life predictions. No significant interactions between footwear and stride length were observed. Running in minimalist shoes increased strains for all metatarsals by 28.7% (SD 6.4%; pRunning at 90% preferred stride length decreased strains for metatarsal 4 by 4.2% (SD 2.0%; p≤0.007), and no differences in probability of failure were observed. Significant increases in metatarsal strains and the probability of failure were observed for recreational runners acutely transitioning to minimalist shoes. Running with a 10% reduction in stride length did not appear to be a beneficial technique for reducing the risk of metatarsal stress fracture, however the increased number of loading cycles for a given distance was not detrimental either. Copyright © 2017 Elsevier Ltd. All rights reserved.

    4. Tensile strained gray tin: Dirac semimetal for observing negative magnetoresistance with Shubnikov-de Haas oscillations

      Science.gov (United States)

      Huang, Huaqing; Liu, Feng

      2017-05-01

      The extremely stringent requirement on material quality has hindered the investigation and potential applications of exotic chiral magnetic effect in Dirac semimetals. Here, we propose that gray tin is a perfect candidate for observing the chiral anomaly effect and Shubnikov-de-Haas (SdH) oscillation at relatively low magnetic field. Based on effective k .p analysis and first-principles calculations, we discover that gray tin becomes a Dirac semimetal under tensile uniaxial strain, in contrast to a topological insulator under compressive uniaxial strain as known before. In this newly found Dirac semimetal state, two Dirac points which are tunable by tensile [001] strains lie in the kz axis and Fermi arcs appear in the (010) surface. Due to the low carrier concentration and high mobility of gray tin, a large chiral anomaly induced negative magnetoresistance and a strong SdH oscillation are anticipated in this half of the strain spectrum. Comparing to other Dirac semimetals, the proposed Dirac semimetal state in the nontoxic elemental gray tin can be more easily manipulated and accurately controlled. We envision that gray tin provides a perfect platform for strain engineering of chiral magnetic effects by sweeping through the strain spectrum from positive to negative and vice versa.

    5. PERBEDAAN PENGARUH MODEL STUDENT TEAMS ACHIEVEMENT DIVISION (STAD DAN NUMBERED HEADS TOGETHER (NHT TERHADAP HASIL BELAJAR MATEMATIKA SISWA KELAS V SD

      Directory of Open Access Journals (Sweden)

      Nur Halimah

      2017-09-01

      Full Text Available This study aimed to determine the significance of the influence differences between the use of Student Teams Achievement Division (STAD model and Numbered Heads Together (NHT model on the 5th grade mathematics learning outcomes in SD Negeri Sumberejo 01 and SD Negeri Sumberejo 02. The type of research used was a quasi experiment with an unpredictable Pretest Posttest design. The subjects of the study were students of grade 5 in SD N Sumberejo 01 as experimental class 1 and grade V SD N of Sumberejo 02 as experiment class 2. The variables in this study consisted of independent variables, namely Student Teams Achievement Division (STAD model, Numbered Heads Together (NHT model and dependent variable was learning outcome. Data collection was done by test technique. The data analysis technique used T test with Independent T test Sample applied to posttest value. Result of t test of posttest value of experiment group 1 and experiment  group 2 showed that the value was in significance 0,019 ˂ 0,05, because the significance ˂ 0,05 hence Ho rejected and Ha accepted with conclusion there was significant difference between the model of STAD and NHT to the result of learning of mathematics at student grade 5 in SD Negeri Sumberejo 01 and SD Sumberejo 02. The significant difference in mathematics learning outcomes was supported by the difference average of two research samples, where the average of learning outcomes on the application of STAD learning model was 77.89, While the average of learning outcomes on the application of NHT learning model was 85.53. This meant that the learning treatment with NHT model has different significant impact compared to the STAD learning model on mathematics learning outcomes of grade 5 SD Sumberejo 01 and SD N Sumberejo 02 Semester II of 2016/2017academic year. Kata Kunci : Student Teams Achievement Division (STAD, Numbered Heads Together (NHT, Learning Outcomes, Mathematics, 5th grade primary school students

    6. MENINGKATKAN HASIL BELAJAR SISWA PADA PEMBELAJARAN PENJASKES DENGAN MENGGUNAKAN MODEL PEMBELAJARAN TEMATIK (PENJASKES, MATEMATIKA, DAN BAHASA INDONESIA) DI KELAS I SD NEGERI UTAMA 2 TARAKAN

      OpenAIRE

      Sri Suparyati

      2011-01-01

      Suparyati, Sri. 2011. Meningkatkan Hasil Belajar Siswa pada Pembelajaran Penjaskes dengan Menggunakan Model Pembelajaran Tematik (Penjaskes, Matematika, dan Bahasa Indonesia) di Kelas I SD Negeri Utama 2 Tarakan. Dalam pelaksanaan penelitian ini menggunakan rancangan penelitian tindakan kelas (classroom action research) dengan dua siklus, siklus I dan siklus II dilaksanakan dalam satu kali tatap muka. Subyek penelitian adalah siswa kelas I-2 SD Negeri Utama 2 Tarakan semester I tahun pembelaj...

    7. Studies on Drosophila radiosensitive strains

      International Nuclear Information System (INIS)

      Varentsova, E.P.; Zakharov, I.A.

      1976-01-01

      45 of radiosensitive strains of Drosophila melanogaster were isolated by Curly/Lobe technique after EMS treatment of Livadia population males. The lethality of non-Curly late larvae after gamma-irradiation (4000r) characterized radiosensitivity strains. Most of them exhibited higher frequency of the spontaneous dominant lethals (up to 69%). The males of 6 strains were semi-sterile. 5 of these strains exhibited higher frequency of X-chromosome non-disjunction

    8. A planet orbiting an sdB star and an M dwarf in 2M 1938+4603

      Directory of Open Access Journals (Sweden)

      Blokesz Adam

      2015-01-01

      Full Text Available We present a preliminary analysis of the 2M 1938+4603 star. It is an eclipsing binary system consisting of a primary sdB component and a secondary M dwarf. The photometric data are dominated by mutual eclipses and a very strong reflection effect. The primary has a fairly rich pulsation spectrum which can be used to study its interior. On the other hand, the pulsations affect the binary trend and vice versa what makes the analysis very difficult. Therefore, we attempted at proper modeling of the light variation due to eclipses and reflection and their removal from the data so it does not affect the Fourier analysis of stellar pulsations. We focus on mid-times of over 16 000 primary and secondary minima, which were used to verify stability of the orbital period. The O-C diagram indicates possible parabolic and sinusoidal variations, commonly explained by period changes caused by evolution and a presence of a third body, respectively.

    9. Electric and magnetic dipole transitions from broad s-wave neutron resonance in even-even sd-shell nuclei

      International Nuclear Information System (INIS)

      Kitazawa, H.; Igashira, M.; Shimizu, M.; Muto, K.; Oda, T.; Achiha, Y.; Lee, Y.; Mukai, N.

      1992-01-01

      Observations have been performed for electromagnetic transitions from the broad s-wave neutron resonances at 658 keV in 24 Mg, at 180 keV in 28 Si, and at 103 keV in 32 S. Capture gamma rays were measured with an anti-Compton NaI(Tl) detector, using a neutron time-of-flight technique. E1 and M1 transitions from those resonances to low-lying states with a strong single-particle character were found. The deduced partial radiative widths for E1 transition are in excellent agreement with the Lane-Mughabghab valence-capture model calculations taking the neutron effective charge, -Ze/A. Moreover, it is shown that essential features of the observed E1 and M1 transitions can be well explained by assuming a configuration-mixing wave function, Ψ i (1/2 + )=a(0 + direct-product 1/2 + )+b(1 + direct-product 1/2 + )+c(1 + direct-product 3/2 + ), for each resonance. The M1 transition strengths are compared also with more detailed shell model calculations in the model space of full (sd) n configurations, using the Wildenthal effective interaction

    10. PENGARUH MEDIA PETA INTERAKTIF TERHADAP PEMAHAMAN DAN HASIL BELAJAR SISWA PADA MATA PELAJARAN IPS KELAS IV SD

      Directory of Open Access Journals (Sweden)

      Maya Kartika Sari

      2016-11-01

      Full Text Available Teaching media has been applied and studied since long ago, but the significance of interactive map media in teaching social science at elementary school has not yet developed. This research is attempted to depict: the students’ mastery on the places and sites, activeness and achievement. The research is conducted under two-cycle class action research on 30 students of four grade, SD Jetis, Bantul, Jogjakarta, at social science subject. The analysis brings about results that: (1 the students’ mastery increases, from 4 students in preliminary reserach becomes 11 in the first cycle and 26 in the second cycle of the research, who master the teaching materials. (2 Students’ activeness increases from 5 students in the prilimary research, to 10 in the first cycle and 28 in the second cycle, who are active in classes. (3 The students’ achievement also increase from 6 students to 15 in the first cycle and 29 in the second cycle, who achieve better mark. The results suggest that interactive map is effective in teaching social science for the students of four grade.   Keywords : teaching social science, interactive map media.

    11. Intruder states in sd-shell nuclei: from 1p-1t to np-nt in Si isotopes

      International Nuclear Information System (INIS)

      Goasduff, A.

      2012-01-01

      New large-scale shell-model calculations with full 1ℎω valence space for the sd-nuclei has been used for the first time to predict lifetimes of positive and negative parity states in neutron rich Si isotopes. The predicted lifetimes (1 - 100 ps) fall in the range of the differential Doppler shift method. Using the demonstrator of the European next generation γ-ray array, AGATA, in coincidence with the large acceptance PRISMA magnetic spectrometer from LNL (Legnaro) and the differential plunger of the University of Cologne, lifetimes of excited states in 32;33 Si and 35;36 S nuclei were measured. In a second step, the nℎω structure in the stable 28 Si nucleus was also studied. 28 Si is an important nucleus in order to understand the competition between mean-field and cluster structures. It displays a wealth of structures in terms of deformation and clustering. Light heavy-ion resonant radiative capture 12 C+ 16 O has been performed at energies below the Coulomb barrier. The measure γ-spectra indicate for the first time at these energies that the strongest part of the resonance decay proceeds though intermediate states around 10 MeV. Comparisons with previous radiative capture studies above the Coulomb barrier have been performed and the results have been interpreted in terms of a favoured feeding of T=1 states in the 28 Si self-conjugate nucleus. (author)

    12. The Structure of the Heavy Calcium Isotopes and the Effective Interaction in the sd-fp Shell

      CERN Multimedia

      Dorvaux, O; Nowacki, F; Courtin, S; Marechal, F; Siiskonen, T M; Perrot, F; Pietri, S B

      2002-01-01

      Nuclei with 40 $<$ A $<$ 56, near the stability line, are very well described in the frame of the shell model. However, when the number of neutrons increases, the situation becomes more complex which explains why the interaction can be found very dissimilar within different calculations. Heavy Ca isotopes, because of the simplicity of their wave-functions, correspond to the optimal choice to fix unambiguously the interaction in this mass region.\\\\ It is proposed to measure the $\\beta$-decay of $^{51, 52, 53}$K with the help of an utmost performing neutron (TONNERRE array) and $\\gamma$- (Miniball clusters) detection, allowing efficient coincidence measurements. This will allow the lowest lying Gamow-Teller states to be located in $^{51, 52, 53}$Ca, and the still unknown properties of natural parity states to be investigated. The awaited results should allow to settle the n-n interaction in the fp shell and the Gnp matrix accross the sd and fp shells, one step farther from stability, by comparison with fu...

    13. PENGEMBANGAN PERANGKAT PEMBELAJARAN PADA MATERI GEOMETRI DAN PENGUKURAN DENGAN PENDEKATAN PENDIDIKAN MATEMATIKA REALISTIK INDONESIA DI SD NEGERI 179 PALEMBANG

      Directory of Open Access Journals (Sweden)

      N. Fahriza Fuadiah

      2013-09-01

      Full Text Available The aims of the research is to produce the set of oriented realistic mathematical education (RME approach material that is valid and practical for teaching in elementary school student of the fifth grade  and have a good potencial effect. PMRI is one of learning approach which dribbles students in understanding mathematics concept by selfcontruction through prior knowledge which is related to daily activity, finding the concept by themselves so that the learning becomes meaningful. The research is a development research and method used in two stages, that are preliminary study (analysis and model development stage and formative study (evaluation and revision stage. The samples were students of fifth grade at SD Negeri 179 Palembang. In technique collecting the data, the writer used interview with the experts, observation by using prototype. The data was analyzed by using descriptive method. The result of data analyses concludes that the development of geometry and measurement prototype for the fifth grade students is valid based on content, construction, and language. It can be conclude from the documentary data that the use of student’s book has been a practical use. The try out tested on students has given potential effect which is the students like to study using realistic mathematical education approach with student activity level of 6.47 in a very high criteria and the average of final mark of  87,17 in a very good criteria. Key words: development research, RME, the set of teaching and learning

    14. BEDA PENGARUH ARKUS KAKI TERHADAP KESEIMBANGAN STATIS ANAK USIA 9-12 TAHUN DI SD NEGERI MOJOLEGI, TERAS, BOYOLALI

      Directory of Open Access Journals (Sweden)

      M. Syafi’i

      2016-12-01

      Full Text Available Tujuan penelitian ini adalah untuk mengetahui perbedaan  normal foot dan flat foot terhadap keseimbangan statis pada anak usia 9-12 tahun. Sejumlah 60 subyek sehat, terbagi menjadi dua kelompok. Masing- masing kelompok 30 orang. Kelompok I adalah Kelompok dengan kondisi arkus normal dan kelompok II adalah kondisi arkus flat foot. Dilakukan di SD Negeri Mojolegi, Teras, Boyolali. Dengan menggunakan alat ukur Wet Test dan One Legged Stance Test. Penelitian ini merupakan non eksperimental cross sectional design. Masing-masing kelompok diuji normalitas data dengan Kolmogorov-Smirnov Test pada Kelompok I menujukkan nilai p>0,05 maka data berdistribusi normal dan Kelompok II menunjukkan nilai p>0,05 maka data berdistribusi normal. Pada kedua kelompok diuji hipotesis dengan Independent T Test dengan hasil p<0,05 maka terdapat perbedaan yang signifikan antara kondisi arkus normal dan kondisi arkus flatfoot dalam mempertahankan keseimbangan statis. Berdasarkan  analisis  statistik penelitian yang telah dilakukan dapat disimpulkan bahwa terdapat perbedaan yang signifikan antara kondisi arkus normal dan kondisi arkus flatfoot dalam mempertahankan posisi keseimbangan statis.

    15. Ectopic expression of Capsicum-specific cell wall protein Capsicum annuum senescence-delaying 1 (CaSD1) delays senescence and induces trichome formation in Nicotiana benthamiana.

      Science.gov (United States)

      Seo, Eunyoung; Yeom, Seon-In; Jo, Sunghwan; Jeong, Heejin; Kang, Byoung-Cheorl; Choi, Doil

      2012-04-01

      Secreted proteins are known to have multiple roles in plant development, metabolism, and stress response. In a previous study to understand the roles of secreted proteins, Capsicum annuum secreted proteins (CaS) were isolated by yeast secretion trap. Among the secreted proteins, we further characterized Capsicum annuum senescence-delaying 1 (CaSD1), a gene encoding a novel secreted protein that is present only in the genus Capsicum. The deduced CaSD1 contains multiple repeats of the amino acid sequence KPPIHNHKPTDYDRS. Interestingly, the number of repeats varied among cultivars and species in the Capsicum genus. CaSD1 is constitutively expressed in roots, and Agrobacterium-mediated transient overexpression of CaSD1 in Nicotiana benthamiana leaves resulted in delayed senescence with a dramatically increased number of trichomes and enlarged epidermal cells. Furthermore, senescence- and cell division-related genes were differentially regulated by CaSD1-overexpressing plants. These observations imply that the pepper-specific cell wall protein CaSD1 plays roles in plant growth and development by regulating cell division and differentiation.

    16. Characterization of Asia 1 sdAb from camels bactrianus (C. bactrianus and conjugation with quantum dots for imaging FMDV in BHK-21 cells.

      Directory of Open Access Journals (Sweden)

      Shuanghui Yin

      Full Text Available Foot-and-mouth disease (FMD, caused by FMD virus (FMDV, is a highly contagious viral disease affecting cloven-hoofed animals. Camelids have a unique immunoglobulin profile, with the smallest functional heavy-chain antibodies (sdAb or VHH naturally devoid of light chains with antigen-binding capacity. We screened and characterized five sdAbs against FMDV by immunized library from C. bactrianus with Asia 1 virus-like particles (VLPs. Three of five recombinant sdAbs were stably expressed in E.coli, remained highly soluble, and were serotype-specific for VP1 protein of FMDV Asia 1 by ELISA. These failed to completely neutralize the Asia 1 virus. According to the KD value of binding affinity to three sdAbs, which ranged from 0.44 to 0.71 nm by SPR, sdAb-C6 was selected and conjugated with Zn/CdSe quantum dots (QDs to form a QDs-C6 probe, which was used to trace and image the subcellular location of FMDV in BHK-21 cells. The results show that FMD virions were observed from 3 h.p.i., and most of virions were distributed on one side of the nucleus in the cytoplasm. We demonstrate the utility of sdAbs as functionalized QDs are powerful tools for FMDV research.

    17. Strain induced adatom correlations

      Science.gov (United States)

      Kappus, Wolfgang

      2012-12-01

      A Born-Green-Yvon type model for adatom density correlations is combined with a model for adatom interactions mediated by the strain in elastic anisotropic substrates. The resulting nonlinear integral equation is solved numerically for coverages from zero to a limit given by stability constraints. W, Nb, Ta and Au surfaces are taken as examples to show the effects of different elastic anisotropy regions. Results of the calculation are shown by appropriate plots and discussed. A mapping to superstructures is tried. Corresponding adatom configurations from Monte Carlo simulations are shown.

    18. Strain actuated aeroelastic control

      Science.gov (United States)

      Lazarus, Kenneth B.

      1992-01-01

      Viewgraphs on strain actuated aeroelastic control are presented. Topics covered include: structural and aerodynamic modeling; control law design methodology; system block diagram; adaptive wing test article; bench-top experiments; bench-top disturbance rejection: open and closed loop response; bench-top disturbance rejection: state cost versus control cost; wind tunnel experiments; wind tunnel gust alleviation: open and closed loop response at 60 mph; wind tunnel gust alleviation: state cost versus control cost at 60 mph; wind tunnel command following: open and closed loop error at 60 mph; wind tunnel flutter suppression: open loop flutter speed; and wind tunnel flutter suppression: closed loop state cost curves.

    19. Penggunaan Model Pembelajaran SAVI Untuk Meningkatkan Prestasi Belajar IPS Pada Siswa Kelas V SD Al Husna Kota Madiun

      Directory of Open Access Journals (Sweden)

      Eka Nofri Ari Yanto

      2017-12-01

      Full Text Available Berdasarkan hasil observasi yang dilakukan peneliti di SD Al Husna (IFDS, diketahui bahwa proses pembelajaran di kelas V masih bersifat konvensional sehingga kurang mengembangkan pola pikir dan kreatifitas siswa. Terdapat beberapa guru khususnya pada mata pelajaran IPS kelas V hanya berceramah dan siswa hanya mendengarkan, mencatat dan menghafalkan materi. Penelitian ini bertujuan untuk meningkatkan prestasi belajar siswa khususnya pada mata pelajaran IPS kelas VA dengan menggunakan model pembelajaran SAVI. Penelitian ini menggunakan metode Penelitian Tindakan Kelas (PTK, prosedur penelitian yang digunakan berupa siklus yang terdiri dari empat tahap yaitu tahap perencanaan, pelaksanaan, observasi dan refleksi.Teknik pengumpulan data yang digunakan adalah tes kognitif dan alat pengumpulan data yang digunakan adalah instrumen soal dan lembar observasi. Hasil analisis data yang diperoleh menunjukkan bahwa terjadi peningkatan pada hasil belajar yang berdampak pada prestasi belajar siswa.Hal ini dapat dilihat dari hasil presentase rata-rata pada siklus I yaitu 75% yang artinya ada 15 dari 20 siswa yang tuntas. Terjadi peningkatan pada siklus yang ke II yaitu 80% yang artinya ada 16 dari 20 siswa yang tuntas dalam pembelajaran. Pada siklus terakhir juga mengalami peningkatan yang signifikan dari siklus sebelumnya yaitu 90% yang artinya ada 18 dari 20 siswa yang tuntas pada siklus terkhir ini. Berdasarkan hasil penelitian, dapat disimpulkan bahwa implementasi model pembelajaran SAVI dapat meningkatkan prestasi belajar siswa pada mata pelajaran IPS kelas V SD Al Husna (IFDS. The result of observation in Al Husna Elementary School (IFDS is learning process on 5th grade which is still conventional so student’s mindset’s development and creativity is less. There are some teachers especially 5th grade’s teachers which only tell the learning material to the students and the students only listen, make a note and memorize the material. This research aims

    20. Long Term Sorption Diffusion Experiment (LTDE-SD). Performance of main in situ experiment and results from water phase measurements

      International Nuclear Information System (INIS)

      Widestrand, Henrik; Byegaard, Johan; Nilsson, Kersti; Hoeglund, Susanne; Gustafsson, Erik; Kronberg, Magnus

      2010-12-01

      The LTDE-SD experiment, (Long Term Sorption Diffusion Experiment) aimed at increasing the scientific knowledge of sorption and diffusion under in situ conditions and to provide data for performance and safety assessment calculations. Performance and results of the in situ experiment phase are presented in the report. In total, 21 radionuclide trace elements and one stable trace element were injected, circulated and sampled for ∼6.5 months in a closed borehole section. The trace elements represented non-sorbing tracers and sorbing tracers for which the sorption was dominated by a cation exchange mechanism, a surface complexation mechanism, or dependent on an electrochemical reduction in order to reach the tetravalent state (oxidation state IV) considered very strongly sorbing. The borehole section in contact with the tracer labelled groundwater consisted in part of a natural fracture surface and a borehole section in the unaltered matrix rock, devoid of natural fractures. Water samples were regularly extracted and analysed for trace element concentration and a few ion exchange speciation and filtered samplings were also conducted. Independent colloid filtering and chemical speciation calculations were performed in support the evaluation. Sorption was demonstrated for a series of elements present in the experiment. The amounts lost of the different respective tracers from the aqueous phase follow very well the general understanding of the relative sorption strength of the tracers, as inferred from e.g. batch sorption experiments and dynamic in situ tracer experiments. The chemical speciation calculations of the different tracers were in line with the results of the ion exchange speciation performed during the experiment. With the exception of UO 2 2+ carbonate complexes formed, no strong indications were obtained that aqueous complexation prevents adsorption under the chemical conditions of the experiment. The 20 nm filtered sampling indicated that radionuclide

    1. Long Term Sorption Diffusion Experiment (LTDE-SD). Performance of main in situ experiment and results from water phase measurements

      Energy Technology Data Exchange (ETDEWEB)

      Widestrand, Henrik; Byegaard, Johan; Nilsson, Kersti; Hoeglund, Susanne; Gustafsson, Erik (Geosigma AB, Uppsala (Sweden)); Kronberg, Magnus (Swedish Nuclear Fuel and Waste Management Co. (Sweden))

      2010-12-15

      The LTDE-SD experiment, (Long Term Sorption Diffusion Experiment) aimed at increasing the scientific knowledge of sorption and diffusion under in situ conditions and to provide data for performance and safety assessment calculations. Performance and results of the in situ experiment phase are presented in the report. In total, 21 radionuclide trace elements and one stable trace element were injected, circulated and sampled for approx6.5 months in a closed borehole section. The trace elements represented non-sorbing tracers and sorbing tracers for which the sorption was dominated by a cation exchange mechanism, a surface complexation mechanism, or dependent on an electrochemical reduction in order to reach the tetravalent state (oxidation state IV) considered very strongly sorbing. The borehole section in contact with the tracer labelled groundwater consisted in part of a natural fracture surface and a borehole section in the unaltered matrix rock, devoid of natural fractures. Water samples were regularly extracted and analysed for trace element concentration and a few ion exchange speciation and filtered samplings were also conducted. Independent colloid filtering and chemical speciation calculations were performed in support the evaluation. Sorption was demonstrated for a series of elements present in the experiment. The amounts lost of the different respective tracers from the aqueous phase follow very well the general understanding of the relative sorption strength of the tracers, as inferred from e.g. batch sorption experiments and dynamic in situ tracer experiments. The chemical speciation calculations of the different tracers were in line with the results of the ion exchange speciation performed during the experiment. With the exception of UO{sub 2} 2+ carbonate complexes formed, no strong indications were obtained that aqueous complexation prevents adsorption under the chemical conditions of the experiment. The 20 nm filtered sampling indicated that

    2. Volatiles Mediated Interactions Between Aspergillus oryzae Strains Modulate Morphological Transition and Exometabolomes.

      Science.gov (United States)

      Singh, Digar; Lee, Choong H

      2018-01-01

      Notwithstanding its mitosporic nature, an improbable morpho-transformation state i. e., sclerotial development (SD), is vaguely known in Aspergillus oryzae . Nevertheless an intriguing phenomenon governing mold's development and stress response, the effects of exogenous factors engendering SD, especially the volatile organic compounds (VOCs) mediated interactions (VMI) pervasive in microbial niches have largely remained unexplored. Herein, we examined the effects of intra-species VMI on SD in A. oryzae RIB 40, followed by comprehensive analyses of associated growth rates, pH alterations, biochemical phenotypes, and exometabolomes. We cultivated A. oryzae RIB 40 (S1 VMI : KACC 44967) opposite a non-SD partner strain, A. oryzae (S2: KCCM 60345), conditioning VMI in a specially designed "twin plate assembly." Notably, SD in S1 VMI was delayed relative to its non-conditioned control (S1) cultivated without partner strain (S2) in twin plate. Selectively evaluating A. oryzae RIB 40 (S1 VMI vs. S1) for altered phenotypes concomitant to SD, we observed a marked disparity for corresponding growth rates (S1 VMI S1) 7days , and biochemical characteristics viz ., protease (S1 VMI > S1) 7days , amylase (S1 VMI > nS1) 3-7 days , and antioxidants (S1 VMI > S1) 7days levels. The partial least squares-discriminant analysis (PLS-DA) of gas chromatography-time of flight-mass spectrometry (GC-TOF-MS) datasets for primary metabolites exhibited a clustered pattern (PLS1, 22.04%; PLS2, 11.36%), with 7 days incubated S1 VMI extracts showed higher abundance of amino acids, sugars, and sugar alcohols with lower organic acids and fatty acids levels, relative to S1. Intriguingly, the higher amino acid and sugar alcohol levels were positively correlated with antioxidant activity, likely impeding SD in S1 VMI . Further, the PLS-DA (PLS1, 18.11%; PLS2, 15.02%) based on liquid chromatography-mass spectrometry (LC-MS) datasets exhibited a notable disparity for post-SD (9-11 days) sample extracts

    3. Volatiles Mediated Interactions Between Aspergillus oryzae Strains Modulate Morphological Transition and Exometabolomes

      Directory of Open Access Journals (Sweden)

      Digar Singh

      2018-04-01

      Full Text Available Notwithstanding its mitosporic nature, an improbable morpho-transformation state i. e., sclerotial development (SD, is vaguely known in Aspergillus oryzae. Nevertheless an intriguing phenomenon governing mold's development and stress response, the effects of exogenous factors engendering SD, especially the volatile organic compounds (VOCs mediated interactions (VMI pervasive in microbial niches have largely remained unexplored. Herein, we examined the effects of intra-species VMI on SD in A. oryzae RIB 40, followed by comprehensive analyses of associated growth rates, pH alterations, biochemical phenotypes, and exometabolomes. We cultivated A. oryzae RIB 40 (S1VMI: KACC 44967 opposite a non-SD partner strain, A. oryzae (S2: KCCM 60345, conditioning VMI in a specially designed “twin plate assembly.” Notably, SD in S1VMI was delayed relative to its non-conditioned control (S1 cultivated without partner strain (S2 in twin plate. Selectively evaluating A. oryzae RIB 40 (S1VMI vs. S1 for altered phenotypes concomitant to SD, we observed a marked disparity for corresponding growth rates (S1VMI < S17days, media pH (S1VMI > S17days, and biochemical characteristics viz., protease (S1VMI > S17days, amylase (S1VMI > nS13–7days, and antioxidants (S1VMI > S17days levels. The partial least squares—discriminant analysis (PLS-DA of gas chromatography—time of flight—mass spectrometry (GC-TOF-MS datasets for primary metabolites exhibited a clustered pattern (PLS1, 22.04%; PLS2, 11.36%, with 7 days incubated S1VMI extracts showed higher abundance of amino acids, sugars, and sugar alcohols with lower organic acids and fatty acids levels, relative to S1. Intriguingly, the higher amino acid and sugar alcohol levels were positively correlated with antioxidant activity, likely impeding SD in S1VMI. Further, the PLS-DA (PLS1, 18.11%; PLS2, 15.02% based on liquid chromatography—mass spectrometry (LC-MS datasets exhibited a notable disparity for post-SD (9

    4. Feasibility of utilizing the SD BIOLINE Onchocerciasis IgG4 rapid test in onchocerciasis surveillance in Senegal

      Science.gov (United States)

      Dieye, Yakou; Barrett, Kelsey L.; Gerth-Guyette, Emily; Di Giorgio, Laura; Golden, Allison; Faulx, Dunia; Kalnoky, Michael; Ndiaye, Marie Khemesse Ngom; Sy, Ngayo; Mané, Malang; Faye, Babacar; Sarr, Mamadou; Dioukhane, Elhadji Mamadou; Peck, Roger B.; Guinot, Philippe; de los Santos, Tala

      2017-01-01

      As effective onchocerciasis control efforts in Africa transition to elimination efforts, different diagnostic tools are required to support country programs. Senegal, with its long standing, successful control program, is transitioning to using the SD BIOLINE Onchocerciasis IgG4 (Ov16) rapid test over traditional skin snip microscopy. The aim of this study is to demonstrate the feasibility of integrating the Ov16 rapid test into onchocerciasis surveillance activities in Senegal, based on the following attributes of acceptability, usability, and cost. A cross-sectional study was conducted in 13 villages in southeastern Senegal in May 2016. Individuals 5 years and older were invited to participate in a demographic questionnaire, an Ov16 rapid test, a skin snip biopsy, and an acceptability interview. Rapid test technicians were interviewed and a costing analysis was conducted. Of 1,173 participants, 1,169 (99.7%) agreed to the rapid test while 383 (32.7%) agreed to skin snip microscopy. The sero-positivity rate of the rapid test among those tested was 2.6% with zero positives 10 years and younger. None of the 383 skin snips were positive for Ov microfilaria. Community members appreciated that the rapid test was performed quickly, was not painful, and provided reliable results. The total costs for this surveillance activity was $22,272.83, with a cost per test conducted at $3.14 for rapid test, $7.58 for skin snip microscopy, and $13.43 for shared costs. If no participants had refused skin snip microscopy, the total cost per method with shared costs would have been around $16 per person tested. In this area with low onchocerciasis sero-positivity, there was high acceptability and perceived value of the rapid test by community members and technicians. This study provides evidence of the feasibility of implementing the Ov16 rapid test in Senegal and may be informative to other country programs transitioning to Ov16 serologic tools. PMID:28972982

    5. Field application of SD bioline malaria Ag Pf/Pan rapid diagnostic test for malaria in Greece.

      Science.gov (United States)

      Tseroni, Maria; Pervanidou, Danai; Tserkezou, Persefoni; Rachiotis, George; Pinaka, Ourania; Baka, Agoritsa; Georgakopoulou, Theano; Vakali, Annita; Dionysopoulou, Martha; Terzaki, Irene; Marka, Andriani; Detsis, Marios; Evlampidou, Zafiroula; Mpimpa, Anastasia; Vassalou, Evdokia; Tsiodras, Sotirios; Tsakris, Athanasios; Kremastinou, Jenny; Hadjichristodoulou, Christos

      2015-01-01

      Greece, a malaria-free country since 1974, has experienced re-emergence of Plasmodium vivax autochthonous malaria cases in some agriculture areas over the last three years. In early 2012, an integrated control programme (MALWEST Project) was launched in order to prevent re-establishment of the disease. In the context of this project, the rapid diagnostic tests (RDT) of SD Bioline Malaria Ag Pf/Pan that detects hrp-2 and pan-LDH antigens were used. The aim of this study was to assess the field application of the RDT for the P. vivax diagnosis in comparison to light microscopy and polymerase chain reaction (PCR). A total of 955 samples were tested with all three diagnostic tools. Agreement of RDT against microscopy and PCR for the diagnosis of P. vivax was satisfactory (K value: 0.849 and 0.976, respectively). The sensitivity, specificity and positive predictive value of RDT against PCR was 95.6% (95% C.I.: 84.8-99.3), 100% (95% C.I.: 99.6-100.0) and 100% (95% CI: 91.7-100.0) respectively, while the sensitivity, specificity and positive predictive value of RDT against microscopic examination was 97.4% (95% C.I.: 86.1-99.6), 99.4% (95% C.I.: 98.6-99.8) and 86.1% (95% CI: 72.1-94.7), respectively. Our results indicate that RDT performed satisfactory in a non-endemic country and therefore is recommended for malaria diagnosis, especially in areas where health professionals lack experience on light microscopy.

    6. Nano-hydroxyapatite particles induce apoptosis on MC3T3-E1 cells and tissue cells in SD rats

      Science.gov (United States)

      Wang, Liting; Zhou, Gang; Liu, Haifeng; Niu, Xufeng; Han, Jingyun; Zheng, Lisha; Fan, Yubo

      2012-04-01

      While the advantages of nanomaterials are being increasingly recognized, their potential toxicity is drawing more and more attention and concern. In this study, we explore the toxicity mechanism of 20-30 nm rod-shaped hydroxyapatite (HA) nanoparticles in vitro and in vivo. The nanoparticles were prepared by precipitation and characterized by IR, XRD and TEM. Concentrations of 0 μg mL-1, 10 μg mL-1, 100 μg mL-1, 1 mg mL-1, and 10 mg mL-1 were applied to the MC3T3-E1 cells for viability (MTT-test). Based on the characteristic differences of the two methods of cell death, the morphological features of the MC3T3-E1 cell line co-cultured with nano-hydroxyapatite (n-HA) (10 mg mL-1) for 24 h were also observed by TEM. Furthermore, important serum biochemical markers and histopathological examinations were used to evaluate the potential toxicological effect of n-HA on the major organs of SD rats injected intraperitoneally with n-HA (33.3 mg kg-1 body weight). In the results, we found cell growth inhibition and apoptosis in MC3T3-E1 cells co-cultured with n-HA. Moreover, apoptosis but not necrosis was illustrated in liver and renal tissue by using histopathology slices and serum biochemical markers. It suggests that apoptosis may be the possible mechanism of n-HA toxicity and provides a better understanding of the biocompatibility of nanomaterials applied in human bone repair.

    7. Feasibility of utilizing the SD BIOLINE Onchocerciasis IgG4 rapid test in onchocerciasis surveillance in Senegal.

      Directory of Open Access Journals (Sweden)

      Yakou Dieye

      2017-10-01

      Full Text Available As effective onchocerciasis control efforts in Africa transition to elimination efforts, different diagnostic tools are required to support country programs. Senegal, with its long standing, successful control program, is transitioning to using the SD BIOLINE Onchocerciasis IgG4 (Ov16 rapid test over traditional skin snip microscopy. The aim of this study is to demonstrate the feasibility of integrating the Ov16 rapid test into onchocerciasis surveillance activities in Senegal, based on the following attributes of acceptability, usability, and cost. A cross-sectional study was conducted in 13 villages in southeastern Senegal in May 2016. Individuals 5 years and older were invited to participate in a demographic questionnaire, an Ov16 rapid test, a skin snip biopsy, and an acceptability interview. Rapid test technicians were interviewed and a costing analysis was conducted. Of 1,173 participants, 1,169 (99.7% agreed to the rapid test while 383 (32.7% agreed to skin snip microscopy. The sero-positivity rate of the rapid test among those tested was 2.6% with zero positives 10 years and younger. None of the 383 skin snips were positive for Ov microfilaria. Community members appreciated that the rapid test was performed quickly, was not painful, and provided reliable results. The total costs for this surveillance activity was $22,272.83, with a cost per test conducted at $3.14 for rapid test, $7.58 for skin snip microscopy, and $13.43 for shared costs. If no participants had refused skin snip microscopy, the total cost per method with shared costs would have been around $16 per person tested. In this area with low onchocerciasis sero-positivity, there was high acceptability and perceived value of the rapid test by community members and technicians. This study provides evidence of the feasibility of implementing the Ov16 rapid test in Senegal and may be informative to other country programs transitioning to Ov16 serologic tools.

    8. Feasibility of utilizing the SD BIOLINE Onchocerciasis IgG4 rapid test in onchocerciasis surveillance in Senegal.

      Science.gov (United States)

      Dieye, Yakou; Storey, Helen L; Barrett, Kelsey L; Gerth-Guyette, Emily; Di Giorgio, Laura; Golden, Allison; Faulx, Dunia; Kalnoky, Michael; Ndiaye, Marie Khemesse Ngom; Sy, Ngayo; Mané, Malang; Faye, Babacar; Sarr, Mamadou; Dioukhane, Elhadji Mamadou; Peck, Roger B; Guinot, Philippe; de Los Santos, Tala

      2017-10-01

      As effective onchocerciasis control efforts in Africa transition to elimination efforts, different diagnostic tools are required to support country programs. Senegal, with its long standing, successful control program, is transitioning to using the SD BIOLINE Onchocerciasis IgG4 (Ov16) rapid test over traditional skin snip microscopy. The aim of this study is to demonstrate the feasibility of integrating the Ov16 rapid test into onchocerciasis surveillance activities in Senegal, based on the following attributes of acceptability, usability, and cost. A cross-sectional study was conducted in 13 villages in southeastern Senegal in May 2016. Individuals 5 years and older were invited to participate in a demographic questionnaire, an Ov16 rapid test, a skin snip biopsy, and an acceptability interview. Rapid test technicians were interviewed and a costing analysis was conducted. Of 1,173 participants, 1,169 (99.7%) agreed to the rapid test while 383 (32.7%) agreed to skin snip microscopy. The sero-positivity rate of the rapid test among those tested was 2.6% with zero positives 10 years and younger. None of the 383 skin snips were positive for Ov microfilaria. Community members appreciated that the rapid test was performed quickly, was not painful, and provided reliable results. The total costs for this surveillance activity was $22,272.83, with a cost per test conducted at $3.14 for rapid test, $7.58 for skin snip microscopy, and $13.43 for shared costs. If no participants had refused skin snip microscopy, the total cost per method with shared costs would have been around $16 per person tested. In this area with low onchocerciasis sero-positivity, there was high acceptability and perceived value of the rapid test by community members and technicians. This study provides evidence of the feasibility of implementing the Ov16 rapid test in Senegal and may be informative to other country programs transitioning to Ov16 serologic tools.

    9. Systems dynamics (SD) strategy for Small Modular Reactor (SMR) marketing - Conquest at the MIT Energy Laboratory (Pres. MIT Energy Initiative)

      Energy Technology Data Exchange (ETDEWEB)

      Woo, T. H. [Yonsei University, Wonju (Korea, Republic of)

      2016-10-15

      This reactor has the specification as the power is 330 MWt pressurized water reactor (PWR) with integral steam generators and advanced safety features. In the plant design, it is planned for electricity generation of 100 MWe and thermal applications of seawater desalination where the life span is a 60-year operation design and three-year refueling cycle. Regarding of the licensing, the standard design was approved from the Korean regulator in mid-2012 and the Korea Atomic Energy Research Institute (KAERI) has a plan to build a demonstration plant to operate from 2017. According to the previous study of the marketing strategy of the Canadian small reactor, Safe LOW-POwer Kritical Experiment (SLOWPOKE) reactor had been investigated in 1988. Therefore, it is interesting to compare SMART and SLOWPOKE. In this work, it is to find out the strategy of the successful marketing of SMART and suggest continuous marketing prospects. There are specifications and parameters of SMART in Tables 1 and 2. The public acceptance (PA) had been studies as safety-public interpretation, SLOWPOKE safety-experience and process, and economics in the previous paper of the SLOWPOKE, which was about the marketing strategy for the commercial nuclear reactor. The highly cognitive networking based dynamical modeling was discussed where the system is treated by a complex and non-linear way. The linear networking of the interested issue was changed by the SD algorithm where the feedback and multiple connections are added to the original networking theory. The non-linear method has shown the complexity of the marketing strategy, especially for the NPP which is the very expensive and safety focused facility.

    10. PENERAPAN PEMBELAJARAN SAINS DENGAN PENDEKATAN SETS PADA MATERI CAHAYA UNTUK MENINGKATKAN HASIL BELAJAR SISWA KELAS V SD

      Directory of Open Access Journals (Sweden)

      Z. Ragil

      2012-02-01

      Full Text Available Penelitian ini dilatarbelakangi oleh nilai rata-rata dan presentase ketuntasan klasikal siswa yang masih rendah pada matapelajaran sains di SD. Untuk mengatasi permasalahan tersebut, diterapkan pembelajaran sains dengan pendekatan SETS(Science, Environment, Technology, Society. SETS adalah visi atau pendekatan pembelajaran yang memiliki fokus utamamemberikan pengalaman penyelidikan pada siswa untuk mendapatkan pengetahuan yang berkaitan dengan sains, lingkungan,teknologi, dan masyarakat serta kesalingketerkaitannya. Penelitian ini bertujuan untuk mendeskripsikan pembelajaran sainsdengan pendekatan SETS yang diterapkan, dan mengetahui peningkatan hasil belajar. Data penelitian berupa hasil belajar kognitifdiperoleh dari test, hasil belajar afektif dan psikomotorik diperoleh dari lembar observasi, untuk mengetahui peningkatan hasilbelajar siswa secara keseluruhan digunakan dalam penelitian ini adalah uji gain. Hasil analisis data menunjukkan adanyapeningkatan hasil belajar kognitif, afektif dan psikomotorik. Dari hasil analisis tersebut dapat disimpulkan bahwa penerapanpembelajaran sains dengan pendekatan SETS dapat meningkatkan hasil belajar siswa. This research was carried out with the background of low average mark and classical mastery percentage of science subject ofelementary school student. With the purpose of the research of describing science lesson with SETS approach to increase learningachievement, the researcher applies SETS approach in the lesson of light material. The data of cognitive learning achievement isfound by using test, while the affective and psychomotor ones are taken from observation sheets. In order to examine the overalllearning achievement, this study uses gain test. The data analysis shows that there is an improvement of cognitive, affective andpsychomotor learning achievements of student after having the lesson. It is concluded that the application of science lesson withSETS approach can increase the students

    11. Time-resolved and volumetric PIV measurements of a transitional separation bubble on an SD7003 airfoil

      Energy Technology Data Exchange (ETDEWEB)

      Burgmann, S.; Dannemann, J.; Schroeder, W. [RWTH Aachen University, Department of Mechanical Engineering, Institute of Aerodynamics, Aachen (Germany)

      2008-04-15

      To comprehensively understand the effects of Kelvin-Helmholtz instabilities on a transitional separation bubble on the suction side of an airfoil regarding as to flapping of the bubble and its impact on the airfoil performance, the temporal and spatial structure of the vortices occurring at the downstream end of the separation bubble is investigated. Since the bubble variation leads to a change of the pressure distribution, the investigation of the instantaneous velocity field is essential to understand the details of the overall airfoil performance. This vortex formation in the reattachment region on the upper surface of an SD7003 airfoil is analyzed in detail at different angles of attack. At a Reynolds number Re{sub c} < 100,000 the laminar boundary layer separates at angles of attack >4 . Due to transition processes, turbulent reattachment of the separated shear layer occurs enclosing a locally confined recirculation region. To identify the location of the separation bubble and to describe the dynamics of the reattachment, a time-resolved PIV measurement in a single light-sheet is performed. To elucidate the spatial structure of the flow patterns in the reattachment region in time and space, a stereo scanning PIV set-up is applied. The flow field is recorded in at least ten successive light-sheet planes with two high-speed cameras enclosing a viewing angle of 65 to detect all three velocity components within a light-sheet leading to a time-resolved volumetric measurement due to a high scanning speed. The measurements evidence the development of quasi-periodic vortex structures. The temporal dynamics of the vortex roll-up, initialized by the Kelvin-Helmholtz (KH) instability, is shown as well as the spatial development of the vortex roll-up process. Based on these measurements a model for the evolving vortex structure consisting of the formation of c-shape vortices and their transformation into screwdriver vortices is introduced. (orig.)

    12. Systems dynamics (SD) strategy for Small Modular Reactor (SMR) marketing - Conquest at the MIT Energy Laboratory (Pres. MIT Energy Initiative)

      International Nuclear Information System (INIS)

      Woo, T. H.

      2016-01-01

      This reactor has the specification as the power is 330 MWt pressurized water reactor (PWR) with integral steam generators and advanced safety features. In the plant design, it is planned for electricity generation of 100 MWe and thermal applications of seawater desalination where the life span is a 60-year operation design and three-year refueling cycle. Regarding of the licensing, the standard design was approved from the Korean regulator in mid-2012 and the Korea Atomic Energy Research Institute (KAERI) has a plan to build a demonstration plant to operate from 2017. According to the previous study of the marketing strategy of the Canadian small reactor, Safe LOW-POwer Kritical Experiment (SLOWPOKE) reactor had been investigated in 1988. Therefore, it is interesting to compare SMART and SLOWPOKE. In this work, it is to find out the strategy of the successful marketing of SMART and suggest continuous marketing prospects. There are specifications and parameters of SMART in Tables 1 and 2. The public acceptance (PA) had been studies as safety-public interpretation, SLOWPOKE safety-experience and process, and economics in the previous paper of the SLOWPOKE, which was about the marketing strategy for the commercial nuclear reactor. The highly cognitive networking based dynamical modeling was discussed where the system is treated by a complex and non-linear way. The linear networking of the interested issue was changed by the SD algorithm where the feedback and multiple connections are added to the original networking theory. The non-linear method has shown the complexity of the marketing strategy, especially for the NPP which is the very expensive and safety focused facility

    13. Scan direction induced charging dynamics and the application for detection of gate to S/D shorts in logic devices

      Science.gov (United States)

      Lei, Ming; Tian, Qing; Wu, Kevin; Zhao, Yan

      2016-03-01

      Gate to source/drain (S/D) short is the most common and detrimental failure mechanism for advanced process technology development in Metal-Oxide-Semiconductor-Field-Effect-Transistor (MOSFET) device manufacturing. Especially for sub-1Xnm nodes, MOSFET device is more vulnerable to gate-S/D shorts due to the aggressive scaling. The detection of this kind of electrical short defect is always challenging for in-line electron beam inspection (EBI), especially new shorting mechanisms on atomic scale due to new material/process flow implementation. The second challenge comes from the characterization of the shorts including identification of the exact shorting location. In this paper, we demonstrate unique scan direction induced charging dynamics (SDCD) phenomenon which stems from the transistor level response from EBI scan at post metal contact chemical-mechanical planarization (CMP) layers. We found that SDCD effect is exceptionally useful for gate-S/D short induced voltage contrast (VC) defect detection, especially for identification of shorting locations. The unique SDCD effect signatures of gate-S/D shorts can be used as fingerprint for ground true shorting defect detection. Correlation with other characterization methods on the same defective location from EBI scan shows consistent results from various shorting mechanism. A practical work flow to implement the application of SDCD effect for in-line EBI monitor of critical gate-S/D short defects is also proposed, together with examples of successful application use cases which mostly focus on static random-access memory (SRAM) array regions. Although the capability of gate-S/D short detection as well as expected device response is limited to passing transistors and pull-down transistors due to the design restriction from standard 6-cell SRAM structure, SDCD effect is proven to be very effective for gate-S/D short induced VC defect detection as well as yield learning for advanced technology development.

    14. Strain differences in ethanol preference and reinforced behaviour: a comparison of two-bottle choice and operant self-administration paradigms.

      Science.gov (United States)

      Wilson, A W; Neill, J C; Costall, B

      1997-02-01

      An animal's volitional consumption of ethanol may be influenced by both genetic and environmental factors. In addition, genetic control of ethanol intake may depend on the test paradigm used. In the present study, performance for, and intake of ethanol in a limited access oral operant paradigm, and preference for ethanol in a two-bottle free choice test in the home-cage were compared in female rats of the heterogeneous Sprague Dawley (SD) and inbred Lewis strains. A smaller proportion of SD rats reached criterion on the self-administration task (four of 10 SD vs eight of 10 Lewis), but those SD rats that did achieve criterion maintained higher levels of responding and greater ethanol intake, relative to the Lewis strain, in the operant self-administration paradigm. Additionally, SD but not Lewis rats exhibited increased locomotor activity and an increase in performance for ethanol compared with water. In marked contrast, Lewis rats exhibited a greater preference for 10% ethanol over water in the two-bottle choice test compared with the SD strain, which preferred water to ethanol. These results suggest that both genotype and test paradigm are involved in the extent to which ethanol serves as a positive reinforcer and that unlike two-bottle choice preference tests, self-administration studies are more highly predictive of the reinforcing properties of ethanol.

    15. Colony Dimorphism in Bradyrhizobium Strains

      Science.gov (United States)

      Sylvester-Bradley, Rosemary; Thornton, Philip; Jones, Peter

      1988-01-01

      Ten isolates of Bradyrhizobium spp. which form two colony types were studied; the isolates originated from a range of legume species. The two colony types differed in the amount of gum formed or size or both, depending on the strain. Whole 7-day-old colonies of each type were subcultured to determine the proportion of cells which had changed to the other type. An iterative computerized procedure was used to determine the rate of switching per generation between the two types and to predict proportions reached at equilibrium for each strain. The predicted proportions of the wetter (more gummy) or larger colony type at equilibrium differed significantly between strains, ranging from 0.9999 (strain CIAT 2383) to 0.0216 (strain CIAT 2469), because some strains switched faster from dry to wet (or small to large) and others switched faster from wet to dry (or large to small). Predicted equilibrium was reached after about 140 generations in strain USDA 76. In all but one strain (CIAT 3030) the growth rate of the wetter colony type was greater than or similar to that of the drier type. The mean difference in generation time between the two colony types was 0.37 h. Doubling times calculated for either colony type after 7 days of growth on the agar surface ranged from 6.0 to 7.3 h. The formation of two persistent colony types by one strain (clonal or colony dimorphism) may be a common phenomenon among Bradyrhizobium strains. Images PMID:16347599

    16. A population of serumdeprivation-induced bone marrow stem cells (SD-BMSC) expresses marker typical for embryonic and neural stem cells

      International Nuclear Information System (INIS)

      Sauerzweig, Steven; Munsch, Thomas; Lessmann, Volkmar; Reymann, Klaus G.; Braun, Holger

      2009-01-01

      The bone marrow represents an easy accessible source of adult stem cells suitable for various cell based therapies. Several studies in recent years suggested the existence of pluripotent stem cells within bone marrow stem cells (BMSC) expressing marker proteins of both embryonic and tissue committed stem cells. These subpopulations were referred to as MAPC, MIAMI and VSEL-cells. Here we describe SD-BMSC (serumdeprivation-induced BMSC) which are induced as a distinct subpopulation after complete serumdeprivation. SD-BMSC are generated from small-sized nestin-positive BMSC (S-BMSC) organized as round-shaped cells in the top layer of BMSC-cultures. The generation of SD-BMSC is caused by a selective proliferation of S-BMSC and accompanied by changes in both morphology and gene expression. SD-BMSC up-regulate not only markers typical for neural stem cells like nestin and GFAP, but also proteins characteristic for embryonic cells like Oct4 and SOX2. We hypothesize, that SD-BMSC like MAPC, MIAMI and VSEL-cells represent derivatives from a single pluripotent stem cell fraction within BMSC exhibiting characteristics of embryonic and tissue committed stem cells. The complete removal of serum might offer a simple way to specifically enrich this fraction of pluripotent embryonic like stem cells in BMSC cultures

    17. Competitiveness and survival of two strains of Glossina palpalis gambiensis in an urban area of Senegal.

      Science.gov (United States)

      Bassène, Mireille Djimangali; Seck, Momar Talla; Pagabeleguem, Soumaïla; Fall, Assane Gueye; Sall, Baba; Vreysen, Marc J B; Gimonneau, Geoffrey; Bouyer, Jérémy

      2017-12-01

      In the Niayes area, located in the west of Senegal, only one tsetse species, Glossina palpalis gambiensis Vanderplank (Diptera: Glossinidae) was present. The Government of Senegal initiated and implemented an elimination programme in this area that included a sterile insect technique (SIT) component. The G. p. gambiensis strain (BKF) mass-reared at the Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES) in Burkina Faso was used for the SIT component. Studies conducted in 2011 in four localities in the Niayes area (Pout, Sébikotane, Diacksao Peul and the Parc de Hann) showed that the BKF strain demonstrated inferior survival in the ecosystem of the Parc de Hann, a forested area in the city centre of the capital Dakar. Therefore, G. p. gambiensis flies from the Niayes area (SEN strain) were colonized. Here we compared the competitiveness and survival of the two strains (BKF and SEN) in the Parc de Hann. Released sterile males of the SEN colony showed a daily mortality rate of 0.08 (SD 0.08) as compared with 0.14 (SD 0.08) for the BKF flies but the difference was not significant (p-value = 0.14). However, the competitiveness of the SEN males was lower (0.14 (SD 0.10)) as compared with that of the BKF males (0.76 (SD 0.11)) (p-value competitiveness of the BKF males is deemed more important for the SIT component, as their shorter survival rates can be easily compensated for by more frequent fly releases.

    18. Diagnostic Accuracy of Spectralis SD OCT Automated Macular Layers Segmentation to Discriminate Normal from Early Glaucomatous Eyes.

      Science.gov (United States)

      Pazos, Marta; Dyrda, Agnieszka Anna; Biarnés, Marc; Gómez, Alicia; Martín, Carlos; Mora, Clara; Fatti, Gianluca; Antón, Alfonso

      2017-08-01

      To evaluate the accuracy of the macular retinal layer segmentation software of the Spectralis spectral-domain (SD) optical coherence tomography (OCT) device (Heidelberg Engineering, Inc., Heidelberg, Germany) to discriminate between healthy and early glaucoma (EG) eyes. Prospective, cross-sectional study. Forty EG eyes and 40 healthy controls were included. All participants were examined using the standard posterior pole and the peripapillary retinal nerve fiber layer (pRNFL) protocols of the Spectralis OCT device. Using an Early Treatment Diagnostic Retinopathy Study circle at the macular level, the automated retinal segmentation software was applied to determine thicknesses of the following parameters: total retinal thickness, inner retinal layer (IRL), macular retinal nerve fiber layer (mRNFL), macular ganglion cell layer (mGCL), macular inner plexiform layer (mIPL), macular inner nuclear layer (mINL), macular outer plexiform layer (mOPL), macular outer nuclear layer (mONL), photoreceptors (PR), and retinal pigmentary epithelium (RPE). The ganglion cell complex (GCC) was determined by adding the mRNFL, mGCL, and mIPL parameters and the ganglion cell layer-inner plexiform layer (mGCL-IPL) was determined by combining the mGCL and mIPL parameters. Thickness of each layer was compared between the groups, and the layer and sector with the best area under the receiver operating characteristic curve (AUC) were identified. Comparison of pRNFL, IRL, mRNFL, mGCL, mIPL, mGCC, mGCL-IPL, mINL, mOPL, mONL, PR, and RPE parameters and total retinal thicknesses between groups for the different areas and their corresponding AUCs. Peripapillary RNFL was significantly thinner in the EG group globally and in all 6 sectors assessed (P < 0.0005). For the macular variables, retinal thickness was significantly reduced in the EG group for total retinal thickness, mIRL, mRNFL, mGCL, and mIPL. The 2 best isolated parameters to discriminate between the 2 groups were pRNFL (AUC, 0.956) and

    19. Strain Pattern in Supercooled Liquids

      Science.gov (United States)

      Illing, Bernd; Fritschi, Sebastian; Hajnal, David; Klix, Christian; Keim, Peter; Fuchs, Matthias

      2016-11-01

      Investigations of strain correlations at the glass transition reveal unexpected phenomena. The shear strain fluctuations show an Eshelby-strain pattern [˜cos (4 θ ) /r2 ], characteristic of elastic response, even in liquids, at long times. We address this using a mode-coupling theory for the strain fluctuations in supercooled liquids and data from both video microscopy of a two-dimensional colloidal glass former and simulations of Brownian hard disks. We show that the long-ranged and long-lived strain signatures follow a scaling law valid close to the glass transition. For large enough viscosities, the Eshelby-strain pattern is visible even on time scales longer than the structural relaxation time τ and after the shear modulus has relaxed to zero.

    20. Effects of weaning by surrogate mothers (ACI) on tumor development in SD rats treated with methylnitrosourea (MNU) and/or N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).

      Science.gov (United States)

      Shiraki, Katsuhisa; Lu, Huimei; Ishimura, Yoshimasa; Kashiwabara, Shoji; Uesaka, Toshihiro; Katoh, Osamu; Watanabe, Hiromitsu

      2002-09-01

      In this experiment, methylnitrosourea (MNU) was administered, followed by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), to assess effects of surrogate mothering on tumor. One or two day old male SD pups were treated with or without 30 mg/kg body weight of MNU and nursed by SD or ACI surrogate mothers for 5 weeks. When 6-weeks-old they were then treated with 100 ppm MNNG or tap water for 16 weeks. The tumor incidence in the MNNG alone group was significantly lower than with MNU alone or MNU+MNNG (p surrogate mothers after treatment with MNU was increased as compared with the SD mother group. Cumulative development of tumors in the ACI surrogate mother group was also delayed (p mother's milk.

    1. Hydrogen production from microbial strains

      Science.gov (United States)

      Harwood, Caroline S; Rey, Federico E

      2012-09-18

      The present invention is directed to a method of screening microbe strains capable of generating hydrogen. This method involves inoculating one or more microbes in a sample containing cell culture medium to form an inoculated culture medium. The inoculated culture medium is then incubated under hydrogen producing conditions. Once incubating causes the inoculated culture medium to produce hydrogen, microbes in the culture medium are identified as candidate microbe strains capable of generating hydrogen. Methods of producing hydrogen using one or more of the microbial strains identified as well as the hydrogen producing strains themselves are also disclosed.

    2. Asymptomatic bacteriuria Escherichia coli strains

      DEFF Research Database (Denmark)

      Hancock, Viktoria; Nielsen, E.M.; Klemm, Per

      2006-01-01

      Urinary tract infections (UTIs) affect millions of people each year. Escherichia coli is the most common organism associated with asymptomatic bacteriuria (ABU) in humans. Persons affected by ABU may carry a particular E. coli strain for extended periods of time without any symptoms. In contrast...... to uropathogenic E. coli (UPEC) that cause symptomatic UTI, very little is known about the mechanisms by which these strains colonize the urinary tract. Here, we have investigated the growth characteristics in human urine as well as adhesin repertoire of nine ABU strains; the ability of ABU strains to compete...

    3. Effects of Weaning by Surrogate Mothers (ACI) on Tumor Development in SD Rats Treatedwith Methylnitrosourea (MNU) and/or N-Methyl-N-nitro-N-nitrosoguanidine (MNNG)

      OpenAIRE

      Shiraki, Katsuhisa; Lu, Huimei; Ishimura, Yoshimasa; Kashiwabara, Shoji; Uesaka, Toshihiro; Katoh, Osamu; Watanabe, Hiromitsu

      2002-01-01

      In this experiment, MNU was administered, followed by MNNG, to assess effects ofsurrogate mothering on tumor. One or two day old male SD pups were treated with or without30mg/kg body weight of methylnitrosourea (MNU) and nursed by SD or ACI surrogate mothersfor 5 weeks. When 6-weeks-old they were then treated with 100ppmN-methyl-N-nitro-N-nitrosoguanidine (MNNG) or tap water for 16 weeks. The tumor incidencein the MNNG alone group was significantly lower than with MNU alone or MNU+MNNG (p

    4. Distributional records of Antarctic fungi based on strains preserved in the Culture Collection of Fungi from Extreme Environments (CCFEE Mycological Section associated with the Italian National Antarctic Museum (MNA

      Directory of Open Access Journals (Sweden)

      Laura Selbmann

      2015-07-01

      Full Text Available This dataset includes information regarding fungal strains collected during several Antarctic expeditions: the Italian National Antarctic Research program (PNRA expeditions “X” (1994/1995, “XII” (1996/1997, “XVII” (2001/2002, “XIX” (2003/2004, “XXVI” (2010/2011, the Czech “IPY Expedition” (2007–2009 and a number of strains donated by E. Imre Friedmann (Florida State University in 2001, isolated from samples collected during the U.S.A. Antarctic Expeditions of 1980-1982. Samples, consisting of colonized rocks, mosses, lichens, sediments and soils, were collected in Southern and Northern Victoria Land of the continental Antarctica and in the Antarctic Peninsula. A total of 259 different strains were isolated, belonging to 32 genera and 38 species, out of which 12 represented new taxa. These strains are preserved in the Antarctic section of the Culture Collection of Fungi from Extreme Environments (CCFEE, which represents one of the collections associated with the Italian National Antarctic Museum (MNA, Section of Genoa, Italy, located at the Laboratory of Systematic Botany and Mycology, Department of Ecological and Biological Sciences (DEB, Tuscia University (Viterbo, Italy. The CCFEE hosts a total of 486 Antarctic fungal strains from worldwide extreme environments. Distributional records are reported here for 259 of these strains. The holotypes of the 12 new species included in this dataset are maintained at CCFEE and in other international collections: CBS-KNAW Fungal Biodiversity Centre (Utrecht, Netherlands; DBVPG, Industrial Yeasts Collection (University of Perugia, Italy; DSMZ, German Collection of Microorganisms and Cell Cultures (Brunswick, Germany; IMI, International Mycological Institute (London, U.K..

    5. TL transgenic mouse strains

      International Nuclear Information System (INIS)

      Obata, Y.; Matsudaira, Y.; Hasegawa, H.; Tamaki, H.; Takahashi, T.; Morita, A.; Kasai, K.

      1993-01-01

      As a result of abnormal development of the thymus of these mice, TCR αβ lineage of the T cell differentiation is disturbed and cells belonging to the TCR γδ CD4 - CD8 - double negative (DN) lineage become preponderant. The γδ DN cells migrate into peripheral lymphoid organs and constitute nearly 50% of peripheral T cells. Immune function of the transgenic mice is severely impaired, indicating that the γδ cells are incapable of participating in these reactions. Molecular and serological analyses of T-cell lymphomas reveal that they belong to the γδ lineage. Tg.Tla a -3-1 mice should be useful in defining the role of TL in normal and abnormal T cell differentiation as well as in the development of T-cell lymphomas, and further they should facilitate studies on the differentiation and function of γδ T cells. We isolated T3 b -TL gene from B6 mice and constructed a chimeric gene in which T3 b -TL is driven by the promoter of H-2K b . With the chimeric gene, two transgenic mouse strains, Tg. Con.3-1 and -2 have been derived in C3H background. Both strains express TL antigen in various tissues including skin. The skin graft of transgenic mice on C3H and (B6 X C3H)F 1 mice were rejected. In the mice which rejected the grafts, CD8 + TCRαβ cytotoxic T cells (CTL) against TL antigens were recognized. The recognition of TL by CTL did not require the antigen presentation by H-2 molecules. The results indicated that TL antigen in the skin becomes a transplantation antigen and behaves like a typical allogeneic MHC class I antigen. The facts that (B6 X C3H)F 1 mice rejected the skin expressing T3 b -TL antigen and induced CTL that killed TL + lymphomas of B6 origin revealed that TL antigen encoded by T3 b -TL is recognized as non-self in B6 mice. Experiments are now extended to analyze immune responses to TL antigen expressed on autochthonous T cell lymphomas. (J.P.N.)

    6. Nutritionally fastidious Ruminococct $ flovefociens : strains

      African Journals Online (AJOL)

      than those obtained in a medium containing rumen fluid. Growth of all strains was remarkably uniform. Where the same inoculum was used, differences in the qualitative com- position of the medium usually had little effect on growth. In contrast, the R. f/avefaciens strains were much more variable in their growth responses.

    7. Haldane model under nonuniform strain

      Science.gov (United States)

      Ho, Yen-Hung; Castro, Eduardo V.; Cazalilla, Miguel A.

      2017-10-01

      We study the Haldane model under strain using a tight-binding approach, and compare the obtained results with the continuum-limit approximation. As in graphene, nonuniform strain leads to a time-reversal preserving pseudomagnetic field that induces (pseudo-)Landau levels. Unlike a real magnetic field, strain lifts the degeneracy of the zeroth pseudo-Landau levels at different valleys. Moreover, for the zigzag edge under uniaxial strain, strain removes the degeneracy within the pseudo-Landau levels by inducing a tilt in their energy dispersion. The latter arises from next-to-leading order corrections to the continuum-limit Hamiltonian, which are absent for a real magnetic field. We show that, for the lowest pseudo-Landau levels in the Haldane model, the dominant contribution to the tilt is different from graphene. In addition, although strain does not strongly modify the dispersion of the edge states, their interplay with the pseudo-Landau levels is different for the armchair and zigzag ribbons. Finally, we study the effect of strain in the band structure of the Haldane model at the critical point of the topological transition, thus shedding light on the interplay between nontrivial topology and strain in quantum anomalous Hall systems.

    8. The System Dynamics Model User Sustainability Explorer (SD-MUSE) user interface: a user-friendly tool for interpreting system dynamic models

      Science.gov (United States)

      Sustainability-based decision making is a challenging process that requires balancing trade-offs among social, economic, and environmental components. System Dynamic (SD) models can be useful tools to inform sustainability-based decision making because they provide a holistic co...

    9. Signal differential-to-noise ratio (SdNR) in the evaluation of radiography techniques for optimisation of the industrial computed radiography

      International Nuclear Information System (INIS)

      Saddock, Aline; Candeias, Janaina P.; Oliveira, Davi F.; Lopes, Ricardo T.

      2007-01-01

      The transition from analog to digital operation which the radiography has gone through, has provided new and important challenges in the way the images are acquired and displayed. There is several acquisition system of digital image, such as for example, the computerized system, which uses Image Plates (IP). This system was used in the accomplishment of this work with the aim to study a technique capable of optimizing the acquisition of digital image. A methodology for the evaluation of image quality is through the parameter signal differential-to- noise ratio (SdNR). However, in order to compare different radiographic techniques through this system it is also necessary to calculate the Figure of Merit (FOM) that in this in case, it is given by the square of the SdNR per unit of applied dose. The method proposed in this work is about the use of IP to carry out SdNR experimental measurements and consequently FOM measurements in applications of the x-ray of pieces in aluminum. This proceeding was performed varying some specific parameters of the system, as high voltage, exposition and the use of filters in the X-rays tube exit. As a result, an SdNR was obtained for each technique, allowing in this way, to verify the behavior of the FOM in each one of them. (author)

    10. LONG-TERM SD-OCT/SLO IMAGING OF NEURORETINA AND RETINAL PIGMENT EPITHELIUM AFTER SUB-THRESHOLD INFRARED LASER TREATMENT OF DRUSEN

      Science.gov (United States)

      MOJANA, FRANCESCA; BRAR, MANPREET; CHENG, LINGYUN; BARTSCH, DIRK-UWE G.; FREEMAN, WILLIAM R.

      2012-01-01

      PURPOSE To determine the long-term effect of sub-threshold diode laser treatment for drusen in patients with non-exudative age-related macular degeneration (AMD) with spectral domain optical coherence tomography combined with simultaneous scanning laser ophthalmoscope (SD-OCT/SLO). METHODS 8 eyes of 4 consecutive AMD patients with bilateral drusen previously treated with sub-threshold diode laser were imaged with SD-OCT/SLO. Abnormalities in the outer retina layers reflectivity as seen with SD-OCT/SLO were retrospectively analyzed and compared with color fundus pictures and autofluorescence images (AF) acquired immediately before and after the laser treatment. RESULTS A focal discrete disruptions in the reflectivity of the outer retinal layers was noted in 29% of the laser lesions. The junction in between the inner and outer segment of the photoreceptor was more frequently affected, with associated focal damage of the outer nuclear layer. Defects of the RPE were occasionally detected. These changes did not correspond to threshold burns on color fundus photography, but corresponded to focal areas of increased AF in the majority of the cases. CONCLUSIONS Sub-threshold diode laser treatment causes long-term disruption of the retinal photoreceptor layer as analyzed by SD-OCT/SLO. The concept that sub-threshold laser treatment can achieve a selected RPE effect without damage to rods and cones may be flawed. PMID:21157398

    11. Paper S12 5 : Self-aligned a-IGZO TFTs : Impact of S/D contacts formation on their Negative-Bias-Illumination-Stress (NBIS) instability

      NARCIS (Netherlands)

      Nag, M.; Steudel, S.; Smout, S.; Bhoolokam, A.; Genoe, J.; Cobb, B.; Kumar, A.; Groeseneken, G.; Heremans, P.

      2015-01-01

      In this work, we present the impact of S/D contact formation, that is, by SiN plasma doping (hydrogen incorporation), metallic reduction (by calcium) and by argon plasma (compositional change) on NBIS instabilities of self-aligned a-IGZO TFTs.

    12. SOLUȚIONAREA „CHESTIUNII ARMENEȘTI” DE CĂTRE GUBERNATORUL BASARABIEI S.D. URUSOV (1903-1904

      Directory of Open Access Journals (Sweden)

      Valentin ARAPU

      2017-08-01

      Full Text Available Gubernatorul Basarabiei S.D. Urusov a soluționat „chestiunea armenească” pe cale amiabilă. Armenii basarabeni au acceptat să cedeze statului rus o parte din bani și proprietăți, păstrându-și intacte privilegiile și statutul de odinioară. În Basarabia, spre deosebire de alte gubernii în care au existat tensiuni în acest sens, grație unei politici abile și tolerante, promovate față de armeni de către S.D. Urusov, procesul de expropriere parțială a comunității armenești s-a desfășurat calm și fără excese.SETTLEMENT OF THE „ARMENIAN ISSUE” BY THE GOVERNOR OF BESSARABIA S.D. URUSOV (1903-1904The governor of Bessarabia S.D. Urusov settled the „Armenian issue” in an amicable way. Armenians from Bessarabiaagreed to cede to Russian state some money and properties, in order to keep intact the privileges and status they held. In Bessarabia, unlike other gubernias, where there were tensions in this regard, thanks to skilful and tolerant policy, promoted by S.D. Urusov, the process of partial expropriation of the Armenian community was held calmly and without excesses.

    13. Functional and Morphological Evaluation of Traumatized Eyes With Berlin's Edema Affecting the Macula Using mfERG, Microperimetry, and SD-OCT.

      Science.gov (United States)

      Boss, Joseph Daniel; Tosi, Joaquin; Glybina, Inna; Tewari, Asheesh; Abrams, Gary W

      2017-02-01

      To describe the structural and functional changes that occur in traumatic Berlin's edema involving the macula through assessment with multifocal electroretinogram (mfERG), microperimetry, fundus photography, and spectral-domain optical coherence tomography (SD-OCT). Retrospective case series of five eyes from four patients with macular traumatic Berlin's edema. Patients underwent baseline mfERG (three eyes), MP1 microperimetry (three eyes), fundus photography (five eyes), and SD-OCT (five eyes). All eyes with Berlin's edema showed abnormal findings on baseline SD-OCT, including disruption and fragmentation of the inner segment/ outer segment layer. In two patients with unilateral blunt ocular trauma who underwent mfERG, there was complete loss of the foveal peak in affected eyes. All three eyes that underwent microperimetry showed depressed retinal sensitivity in the area of Berlin's edema. SD-OCT, microperimetry, and mfERG can be used to help diagnose, stratify traumatic severity, and follow structural and functional progression over time in patients with Berlin's edema. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:114-121.]. Copyright 2017, SLACK Incorporated.

    14. Detailed Morphological Changes of Foveoschisis in Patient with X-Linked Retinoschisis Detected by SD-OCT and Adaptive Optics Fundus Camera

      Directory of Open Access Journals (Sweden)

      Keiichiro Akeo

      2015-01-01

      Full Text Available Purpose. To report the morphological and functional changes associated with a regression of foveoschisis in a patient with X-linked retinoschisis (XLRS. Methods. A 42-year-old man with XLRS underwent genetic analysis and detailed ophthalmic examinations. Functional assessments included best-corrected visual acuity (BCVA, full-field electroretinograms (ERGs, and multifocal ERGs (mfERGs. Morphological assessments included fundus photography, spectral-domain optical coherence tomography (SD-OCT, and adaptive optics (AO fundus imaging. After the baseline clinical data were obtained, topical dorzolamide was applied to the patient. The patient was followed for 24 months. Results. A reported RS1 gene mutation was found (P203L in the patient. At the baseline, his decimal BCVA was 0.15 in the right and 0.3 in the left eye. Fundus photographs showed bilateral spoke wheel-appearing maculopathy. SD-OCT confirmed the foveoschisis in the left eye. The AO images of the left eye showed spoke wheel retinal folds, and the folds were thinner than those in fundus photographs. During the follow-up period, the foveal thickness in the SD-OCT images and the number of retinal folds in the AO images were reduced. Conclusions. We have presented the detailed morphological changes of foveoschisis in a patient with XLRS detected by SD-OCT and AO fundus camera. However, the findings do not indicate whether the changes were influenced by topical dorzolamide or the natural history.

    15. Pin clad strains in Phenix

      International Nuclear Information System (INIS)

      Languille, A.

      1979-07-01

      The Phenix reactor has operated for 4 years in a satisfactory manner. The first 2 sub-assembly loadings contained pins clad in solution treated 316. The principal pin strains are: diametral strain (swelling and irradiation creep), ovality and spiral bending of the pin (interaction of wire and pin cluster and wrapper). A pin cluster irradiated to a dose of 80 dpa F reached a pin diameter strain of 5%. This strain is principally due to swelling (low fission gas pressure). The principal parameters governing the swelling are instantaneous dose, time and temperature for a given type of pin cladding. Other types of steel are or will be irradiated in Phenix. In particular, cold-worked titanium stabilised 316 steel should contribute towards a reduction in the pin clad strains and increase the target burn-up in this reactor. (author)

    16. Probiotic Properties of Lactobacillus Strains Isolated from Tibetan Kefir Grains

      Science.gov (United States)

      Zheng, Yongchen; Lu, Yingli; Wang, Jinfeng; Yang, Longfei; Pan, Chenyu; Huang, Ying

      2013-01-01

      The objective of this study was to evaluate the functional properties of lactic acid bacteria (LAB) isolated from Tibetan kefir grains. Three Lactobacillus isolates identified as Lactobacillus acidophilus LA15, Lactobacillus plantarum B23 and Lactobacillus kefiri D17 that showed resistance to acid and bile salts were selected for further evaluation of their probiotic properties. The 3 selected strains expressed high in vitro adherence to Caco-2 cells. They were sensitive to gentamicin, erythromycin and chloramphenicol and resistant to vancomycin with MIC values of 26 µg/ml. All 3 strains showed potential bile salt hydrolase (BSH) activity, cholesterol assimilation and cholesterol co-precipitation ability. Additionally, the potential effect of these strains on plasma cholesterol levels was evaluated in Sprague-Dawley (SD) rats. Rats in 4 treatment groups were fed the following experimental diets for 4 weeks: a high-cholesterol diet, a high-cholesterol diet plus LA15, a high-cholesterol diet plus B23 or a high-cholesterol diet plus D17. The total cholesterol, triglyceride and low-density lipoprotein cholesterol levels in the serum were significantly (P<0.05) decreased in the LAB-treated rats compared with rats fed a high-cholesterol diet without LAB supplementation. The high-density lipoprotein cholesterol levels in groups B23 and D17 were significantly (P<0.05) higher than those in the control and LA15 groups. Additionally, both fecal cholesterol and bile acid levels were significantly (P<0.05) increased after LAB administration. Fecal lactobacilli counts were significantly (P<0.05) higher in the LAB treatment groups than in the control groups. Furthermore, the 3 strains were detected in the rat small intestine, colon and feces during the feeding trial. The bacteria levels remained high even after the LAB administration had been stopped for 2 weeks. These results suggest that these strains may be used in the future as probiotic starter cultures for manufacturing

    17. Strain expansion-reduction approach

      Science.gov (United States)

      Baqersad, Javad; Bharadwaj, Kedar

      2018-02-01

      Validating numerical models are one of the main aspects of engineering design. However, correlating million degrees of freedom of numerical models to the few degrees of freedom of test models is challenging. Reduction/expansion approaches have been traditionally used to match these degrees of freedom. However, the conventional reduction/expansion approaches are only limited to displacement, velocity or acceleration data. While in many cases only strain data are accessible (e.g. when a structure is monitored using strain-gages), the conventional approaches are not capable of expanding strain data. To bridge this gap, the current paper outlines a reduction/expansion technique to reduce/expand strain data. In the proposed approach, strain mode shapes of a structure are extracted using the finite element method or the digital image correlation technique. The strain mode shapes are used to generate a transformation matrix that can expand the limited set of measurement data. The proposed approach can be used to correlate experimental and analytical strain data. Furthermore, the proposed technique can be used to expand real-time operating data for structural health monitoring (SHM). In order to verify the accuracy of the approach, the proposed technique was used to expand the limited set of real-time operating data in a numerical model of a cantilever beam subjected to various types of excitations. The proposed technique was also applied to expand real-time operating data measured using a few strain gages mounted to an aluminum beam. It was shown that the proposed approach can effectively expand the strain data at limited locations to accurately predict the strain at locations where no sensors were placed.

    18. Automated geographic atrophy segmentation for SD-OCT images using region-based C-V model via local similarity factor.

      Science.gov (United States)

      Niu, Sijie; de Sisternes, Luis; Chen, Qiang; Leng, Theodore; Rubin, Daniel L

      2016-02-01

      Age-related macular degeneration (AMD) is the leading cause of blindness among elderly individuals. Geographic atrophy (GA) is a phenotypic manifestation of the advanced stages of non-exudative AMD. Determination of GA extent in SD-OCT scans allows the quantification of GA-related features, such as radius or area, which could be of important value to monitor AMD progression and possibly identify regions of future GA involvement. The purpose of this work is to develop an automated algorithm to segment GA regions in SD-OCT images. An en face GA fundus image is generated by averaging the axial intensity within an automatically detected sub-volume of the three dimensional SD-OCT data, where an initial coarse GA region is estimated by an iterative threshold segmentation method and an intensity profile set, and subsequently refined by a region-based Chan-Vese model with a local similarity factor. Two image data sets, consisting on 55 SD-OCT scans from twelve eyes in eight patients with GA and 56 SD-OCT scans from 56 eyes in 56 patients with GA, respectively, were utilized to quantitatively evaluate the automated segmentation algorithm. We compared results obtained by the proposed algorithm, manual segmentation by graders, a previously proposed method, and experimental commercial software. When compared to a manually determined gold standard, our algorithm presented a mean overlap ratio (OR) of 81.86% and 70% for the first and second data sets, respectively, while the previously proposed method OR was 72.60% and 65.88% for the first and second data sets, respectively, and the experimental commercial software OR was 62.40% for the second data set.

    19. Toros sediri (Cedrus libani A. Rich. ağaçlandırmalarının gelişimi ile yetişme ortamı özellikleri arasındaki ilişkiler

      Directory of Open Access Journals (Sweden)

      Rıza KARATAŞ

      2017-07-01

      Full Text Available Bu çalışma, Eskişehir, Afyonkarahisar ve Ankara illerindeki toros sediri (Cedrus libani A. Rich. ağaçlandırmalarının boy gelişimi ile bazı yetişme ortamı özellikleri arasındaki ilişkileri belirlemek amacıyla yapılmıştır. Örneklemeler bakı, yükselti, eğim, yamaç konumu ve meşcere gelişimi bakımından farklılık gösteren 55 alanda yürütülmüştür. Her örnek alanda meşcere üst boyunda bulunan bir ağaç kesilmiş ve toprak çukuru açılarak belirlenen horizonlardan toprak örnekleri alınmıştır. Laboratuvarda toprak örneklerinin bazı fiziksel ve kimyasal özellikleri belirlenmiştir. Toros sediri ağaçlandırmalarının gelişimi ile iklim özellikleri arasındaki ilişkileri belirlemek amacıyla örnek alanlara en yakın mesafede bulunan meteoroloji istasyonu verileri kullanılmıştır. Örnek alanlardaki ağaçların üst boy değerleri ile edafik, klimatik ve fizyografik faktörler arasındaki ilişkiler korelasyon, aşamalı regresyon ve regresyon ağacı yöntemleri ile değerlendirilmiştir.Örnek alanlardaki ağaçların üst boy değerleri ile fizyografik yetişme ortamı faktörlerinden enlem ve yamaç konumu; iklim özelliklerinden ortalama yüksek sıcaklık, potansiyel evapotranspirasyon, su fazlası, en soğuk ayın ortalama sıcaklığı, en sıcak ayın ortalama sıcaklığı ve dört yaz ayının ortalama sıcaklığı; toprak özelliklerinden toz miktarı arasında istatistiksel bakımdan önemli ilişkiler bulunmuştur.Sedir ağaçlandırmalarının boy büyümesi aşamalı regresyon analizi ve regresyon ağacı tekniği kullanılarak modellenmiştir. Uygulanan bu analizler sonucunda, boy gelişimini en iyi açıklayan kestirim modeli %65,6 ile regresyon ağacı tekniği kullanılarak elde edilmiştir.

    20. Health-promoting lifestyles and related factors among pregnant women/Gebelerde sağlıklı yaşam biçimi davranışları ve ilişkili faktörler

      Directory of Open Access Journals (Sweden)

      Güliz Onat

      2014-08-01

      Full Text Available AbstractObjective: A health-promoting lifestyle has an especially important role during pregnancy due to its direct link to healthy births, and to low maternal-fetal mortality and morbidity rates. The objectives of our study are to determine and analyse the health-promoting lifestyles and related factors in pregnant women. Methods: This descriptive study was carried out on 255 pregnant women in the city of Usak in Turkey, using the Health-Promoting-Lifestyle-Profile-II-(HPLP. Frequencies, percentage distributions, t tests, and the Mann Whitney U test and ANOVA were used to analyze the results. Results: The mean age of the pregnant women was 26.7±5.1 and their mean gestational week was 25.2±10.9. The mean total score on the HPLP was 130.7±20.0. The lowest score was for “physical activity” (14.4±5.0. The highest score was for “psychological wellbeing” (26.18±4.2. Smoking prevalence among the study population was 17% before the pregnancy,  and 3.9% during the pregnancy (with an average of 4 cigarettes/day. During the pregnancy diet habits improved. The rate of giving up smoking was high. Women also sought further knowledge about pregnancy and birth. Conclusions: In pregnant women the HPLP score was upper to intermediate in level. Of the women who participated in the survey, those that were unemployed, had a lower level of education, and those who had considered abortion were found to be at a higher risk of not having a health promoting life style. This finding provides a unique insight in identifying the risk group for health care providers who work at an antenatal clinic. Health caregivers should pay more attention to this risk group when evaluating healthy lifestyles during whole pregnancy. Key Words: Health-Promoting Lifestyles; pregnant women; Health Promoting Lifestyle Profile-IIÖzetAmaç: Sağlıklı yaşam biçimi davranışları; sağlıklı ve canlı bir doğum yapma, anne-yenidoğan mortalite ve morbidite oranını azaltma

    1. Effect of straining on diaphragmatic crura with identification of the straining-crural reflex. The "reflex theory" in gastroesophageal competence

      Directory of Open Access Journals (Sweden)

      El Sibai Olfat

      2004-09-01

      Full Text Available Abstract Background The role of the crural diaphragm during increased intra-abdominal pressure is not exactly known. We investigated the hypothesis that the crural diaphragm undergoes reflex phasic contraction on elevation of the intra-abdominal pressure with a resulting increase of the lower esophageal pressure and prevention of gastro-esophageal reflux. Methods The esophageal pressure and crural diaphragm electromyographic responses to straining were recorded in 16 subjects (10 men, 6 women, age 36.6 ± 11.2 SD years during abdominal hernia repair. The electromyogram of crural diaphragm was recorded by needle electrode inserted into the crural diaphragm, and the lower esophageal pressure by a saline-perfused catheter. The study was repeated after crural anesthetization and after crural infiltration with saline. Results The crural diaphragm exhibited resting electromyographic activity which showed a significant increase on sudden (coughing, p Conclusions Straining effected an increase of the electromyographic activity of the crural diaphragm and of the lower esophageal pressure. This effect is suggested to be reflex in nature and to be mediated through the "straining-crural reflex". The crural diaphragm seems to play a role in the lower esophageal competence mechanism. Further studies are required to assess the clinical significance of the current results in gastro-esophageal reflux disease and hiatus hernia.

    2. Intestinal metaplasia induced by x-irradiation in different strains of rats

      International Nuclear Information System (INIS)

      Watanabe, Hiromitsu; Naito, Masashi; Kawashima, Kengo; Ito, Akihiro

      1985-01-01

      Attempts were made to examine strain differences in the susceptibility of rats to intestinal metaplasia induced by X-irradiation. The gastric regions of 4 inbred male rats (SHR, F344, WKY, and LEW strains) in 5-week-old and 2 random bred male rats (SD, and WIS strains) were irradiated with a total dose of 20 Gy X-ray given in two equal fractions separated by three days. Upon sacrifice at 6 months after the last irradiation, the number of intestinal metaplastic crypts with positive reaction to alkaline phosphatase (ALP) appeared highest in the SHR and lowest in the WIS rats. Morphologically, the number of crypts with intestinal metaplasia in whole glandular stomachs of SHR, WIS, F344, and SD rats were higher than those in WKY and LEW rats. In the pyloric gland, it was highest in WIS rats, while in the fundic gland it was highest in SHR rats. The results show that the appearance and location of intestinal metaplasia by X-irradiation are greatly influenced by the strain of the rat. (author)

    3. Roll bonding of strained aluminium

      DEFF Research Database (Denmark)

      Staun, Jakob M.

      2003-01-01

      This report investigates roll bonding of pre-strained (å ~ 4) aluminium sheets to produce high strain material from high purity aluminium (99.996%) and commercial pure aluminium (99.6%). The degree of bonding is investigated by optical microscopy and ultrasonic scanning. Under the right...... of the cross rolled volume fraction is found. To further asses this effect, and the anisotropy, it is necessary to acquire knowledge about both texture and microstructure, e.g. by TEM. Roll bonding of pre-strained aluminium is found to be a possible alternative to ARB in the quest for ultra-fine grained...

    4. Strain fluctuations and elastic constants

      Energy Technology Data Exchange (ETDEWEB)

      Parrinello, M.; Rahman, A.

      1982-03-01

      It is shown that the elastic strain fluctuations are a direct measure of elastic compliances in a general anisotropic medium; depending on the ensemble in which the fluctuation is measured either the isothermal or the adiabatic compliances are obtained. These fluctuations can now be calculated in a constant enthalpy and pressure, and hence, constant entropy, ensemble due to recent develpments in the molecular dynamics techniques. A calculation for a Ni single crystal under uniform uniaxial 100 tensile or compressive load is presented as an illustration of the relationships derived between various strain fluctuations and the elastic modulii. The Born stability criteria and the behavior of strain fluctuations are shown to be related.

    5. Strain accumulation in quasicrystalline solids

      International Nuclear Information System (INIS)

      Nori, F.; Ronchetti, M.; Elser, V.

      1988-01-01

      We study the relaxation of 2D quasicrystalline elastic networks when their constituent bonds are perturbed homogeneously. Whereas ideal, quasiperiodic networks are stable against such perturbations, we find significant accumulations of strain in a class of disordered networks generated by a growth process. The grown networks are characterized by root mean square phason fluctuations which grow linearly with system size. The strain accumulation we observe in these networks also grows linearly with system size. Finally, we find a dependence of strain accumulation on cooling rate

    6. Universal Unitarity Triangle 2016 and the tension between ΔM{sub s,d} and ε{sub K} in CMFV models

      Energy Technology Data Exchange (ETDEWEB)

      Blanke, Monika [Karlsruhe Institute of Technology, Institut fur Kernphysik, Eggenstein-Leopoldshafen (Germany); Karlsruhe Institute of Technology, Institut fur Theoretische Teilchenphysik, Karlsruhe (Germany); Buras, Andrzej J. [TUM-IAS, Garching (Germany); TUM, Physik Department, Garching (Germany)

      2016-04-15

      Motivated by the recently improved results from the Fermilab Lattice and MILC Collaborations on the hadronic matrix elements entering ΔM{sub s,d} in B{sup 0}{sub s,d}- anti B{sup 0}{sub s,d} mixing, we determine the universal unitarity triangle (UUT) in models with constrained minimal flavour violation (CMFV). Of particular importance are the very precise determinations of the ratio vertical stroke V{sub ub} vertical stroke / vertical stroke V{sub cb} vertical stroke = 0.0864 ± 0.0025 and of the angle γ = (62.7 ± 2.1) {sup circle}. They follow in this framework from the experimental values of ΔM{sub d}/ΔM{sub s} and of the CP-asymmetry S{sub ψK{sub S}}. As in CMFV models the new contributions to meson mixings can be described by a single flavour-universal variable S(v), we next determine the CKM matrix elements vertical stroke V{sub ts} vertical stroke, vertical stroke V{sub td} vertical stroke, vertical stroke V{sub cb} vertical stroke and vertical stroke V{sub ub} vertical stroke as functions of S(v) using the experimental value of ΔM{sub s} as input. The lower bound on S(v) in these models, derived by us in 2006, implies then upper bounds on these four CKM elements and on the CP-violating parameter ε{sub K}, which turns out to be significantly below its experimental value. This strategy avoids the use of tree-level determinations of vertical stroke V{sub ub} vertical stroke and vertical stroke V{sub cb} vertical stroke, which are presently subject to considerable uncertainties. On the other hand, if ε{sub K} is used instead of ΔM{sub s} as input, ΔM{sub s,d} are found to be significantly above the data. In this manner we point out that the new lattice data have significantly sharpened the tension between ΔM{sub s,d} and ε{sub K} within the CMFV framework. This implies the presence of new physics contributions beyond this framework that are responsible for the breakdown of the flavour universality of the function S(v). We also present the

    7. Strain localisation in granular media

      OpenAIRE

      Desrues , Jacques

      1984-01-01

      This study is devoted to strain localisation in Granular materials. Both experimental and theoretical results have been obtained.The first part of the thesis is a review of the methods and theories about rupture in sols mechanics and more generally, in solid mechanics. The classical framework of Shear Band analysis is presented, and the main results available for different classes of materials are discussed.The second part describes an experimental study of strain localisation in sand specime...

    8. DARPA Antibody Technology Program Standardized Test Bed for Antibody Characterization: Characterization of an MS2 sdAb Produced by U.S. Naval Research Laboratory

      Science.gov (United States)

      2016-10-01

      depict a sigmoidal curve, which is indicative of a valid size distribution. The regularization graphs (Figures 2B and 3B) illustrate the...Figure 1) was typical for an sdAb. DLS was used in conjunction with the Experion and NanoDrop systems to illustrate how the protein behaved in...DISTRIBUTION LIST The following individuals and organizations were provided with one Adobe portable document format (pdf) electronic version of this

    9. Validity of the M-3Y force equivalent G-matrix element for the calculations of nuclear structure in the s-d shell

      International Nuclear Information System (INIS)

      Song Hong-qiu; Wang Zixing; Cai Yanhuang; Huang Weizhi

      1987-01-01

      The matrix elements of the M-3Y force are adopted as the equivalent G-matrix elements and the folded diagram method is used to calculate the spectra of 18 O and 18 F. The results show that the matrix elements of the M-3Y force as the equivalent G-matrix elements are suitable for microscopic calculations of the nuclei in the s-d shell

    10. Penerapan Metode Pembelajaran Diskusi Dan Resitasi Dalam Meningkatkan Hasil Belajar Pendidikan Agama Hindu Siswa Kelas Iv Sd Negeri 2 Tumbu Karangasem

      Directory of Open Access Journals (Sweden)

      Ida Ayu Putu Suci Lestari

      2018-02-01

      Full Text Available This study aims: (1 to know the application of the use of methods of discussion and recitation can improve the learning outcomes of Hindu religious education fourth graders Elementary School 2 Tumbu. (2 to find out constraints faced in using the method of assignment and recitation in the learning of Hindu religious education fourth grade students of SD Negeri 2 Tumbu.The type of this research is Classroom Action Research (PTK with the subject of this research is the fourth grader of SD Negeri 2 Tumbu, the Hindu of 17 people from 22 students, consist of 10 men, and 7 women. The research was conducted at SD Negeri 2 Tumbu Karangasem. This research was conducted in two cycles. One cycle consists of preparation, execution, observation and reflection. Data collection is done by test method. Then the data is analyzed by quantitative descriptive technique.The results of this study is an increase in learning outcomes, the initial reflection of the average learning outcomes of Hindu religious education amounted to 54.7 with 29,41% complete learning. Then, in the first cycle the average learning outcomes of Hindu religious education increased to 69.4 and the classical completeness of 64.71% is still less than the classical completeness set 85%. Thus, learning in cycle I has not been completed. In cycle II the average learning outcomes of Hindu religious education increased to 79.1 and 100% classical completeness, thus the learning cycle II completed.

    11. An analytical spatial reconstruction algorithm for the SD-SGF-CN hybrid nodal method for one-speed X,Y-geometry SN eigenvalue problems

      International Nuclear Information System (INIS)

      Menezes, Welton Alves; Alves Filho, Hermes; Barros, Ricardo C.

      2009-01-01

      In this paper the X,Y-geometry SD-SGF-CN spectral nodal method, cf. spectral diamond-spectral Green's function-constant nodal, is used to determine the one-speed node-edge average angular fluxes in heterogeneous domains. This hybrid spectral nodal method uses the spectral diamond (SD) auxiliary equation for the multiplying regions and the spectral Green's function (SGF) auxiliary equation for the non-multiplying regions of the domain. Moreover, we consider constant approximations for the transverse-leakage terms in the transverse integrated S N nodal equations. We solve the SD-SGF-CN equations using the one-node block inversion (NBI) iterative scheme, which uses the most recent estimates available for the node-entering fluxes to evaluate the node-exiting fluxes in the directions that constitute the incoming fluxes for the adjacent node. Using these results, we offer an algorithm for analytical reconstruction of the coarse-mesh nodal solution within each spatial node, as localized numerical solutions are not generated by usual accurate nodal methods. Numerical results are presented to illustrate the accuracy of the present algorithm. (author)

    12. O ensino da colocação pronominal: aplicação de SD em turmas de terceiro ano do ensino médio

      Directory of Open Access Journals (Sweden)

      Denise Lino de Araújo

      2014-12-01

      Full Text Available The purpose of this article is to describe and analyze a teaching experience on pronoun placement in two groups of 3rd year of high school. The experience was guided by the concepts of Teaching Sequence (Dolz, Noverraz, Schneuwly, 2004, Language Analysis (Kemiac and Lino de Araujo, 2010 and linguistic variation (Patriot, 2009, and Bagno, 2013. This experience focuses on the teaching of linguistic usage analysis of cases of enclisis, proclisis and mesoclisis, in many situations use; for this, the notion ofTS was reviewed and, based on Cunha (2012, it is understood as a set of organized activities to achieve a learning goal. The data analyzed stem from the ongoing evaluation of the SD, which led to the redirection of planning. The results indicate that the initial and final simulated were not the best indicators of learning. An activity of fixation made on the sixth module of SD presented the most reliable indicators of learning. Thus the conclusion is that diagnostics can not function as good indicators for the evaluation of a SD.

    13. Glycoprotein 5 of porcine reproductive and respiratory syndrome virus strain SD16 inhibits viral replication and causes G2/M cell cycle arrest, but does not induce cellular apoptosis in Marc-145 cells

      International Nuclear Information System (INIS)

      Mu, Yang; Li, Liangliang; Zhang, Beibei; Huang, Baicheng; Gao, Jiming

      2015-01-01

      Cell apoptosis is common after infection with porcine reproductive and respiratory syndrome virus (PRRSV). PRRSV GP5 has been reported to induce cell apoptosis. To further understand the role of GP5 in PRRSV induced cell apoptosis, we established Marc-145 cell lines stably expressing full-length GP5, GP5 Δ84-96 (aa 84-96 deletion), and GP5 Δ97-119 (aa 97-119 deletion). Cell proliferation, cell cycle progression, cell apoptosis and virus replication in these cell lines were evaluated. Neither truncated nor full-length GP5 induced cell apoptosis in Marc-145 cells. However, GP5 Δ97-119 , but not full-length or GP5 Δ84-96 , induced a cell cycle arrest at the G2/M phase resulting in a reduction in the growth of Marc-145 cells. Additionally, GP5 Δ84-96 inhibited the replication of PRRSV in Marc-145 cells through induction of IFN-β. These findings suggest that PRRSV GP5 is not responsible for inducing cell apoptosis in Marc-145 cells under these experimental conditions; however it has other important roles in virus/host cell biology. - Highlights: • Marc-145 cell lines stable expression PRRSV GP5 or truncated GP5 were constructed. • GP5 Δ97-119 expression in Marc-145 cell induced cell cycle arrest at G2/M phase. • Expression of GP5 and truncated GP5 could not induce Marc-145 cells apoptosis. • PRRSV replication in Marc-145-GP5 Δ84-96 was significantly inhibited

    14. Effects of Onion (Allium cepa L. Extract Administration on Intestinal α-Glucosidases Activities and Spikes in Postprandial Blood Glucose Levels in SD Rats Model

      Directory of Open Access Journals (Sweden)

      Sun-Ho Kim

      2011-06-01

      Full Text Available Diets high in calories and sweetened foods with disaccharides frequently lead to exaggerated postprandial spikes in blood glucose. This state induces immediate oxidant stress and free radicals which trigger oxidative stress-linked diabetic complications. One of the therapeutic approaches for decreasing postprandial hyperglycemia is to retard absorption of glucose by the inhibition of carbohydrate hydrolyzing enzymes,α-amylase and α-glucosidases, in the digestive organs. Therefore, the inhibitory activity of Korean onion (Allium cepa L. extract against rat intestinal α-glucosidases, such as sucrase, maltase, and porcine pancreatic α-amylase were investigated in vitro and in vivo. The content of quercetin in ethyl alcohol extract of onion skin (EOS was 6.04 g/100 g dried weight of onion skin. The in vitro half-maximal inhibitory concentrations (IC50 of EOS and quercetin, a major phenolic in onion, on rat intestinal sucrase were 0.40 and 0.11 mg/mL, respectively. The postprandial blood glucose lowering effects of EOS and quercetin were compared to a known type 2 diabetes drug (Acarbose, a strong α-glucosidase inhibitor in the Sprague-Dawley (SD rat model. In rats fed on sucrose, EOS significantly reduced the blood glucose spike after sucrose loading. The area under the blood glucose-time curve (AUClast in EOS-treated SD rats (0.5 g-EOS/kg was significantly lower than in untreated SD rats (259.6 ± 5.1 vs. 283.1 ± 19.2 h·mg/dL. The AUClast in quercetin-treated SD rats (0.5 g-quercetin/kg was similar to in EOS-treated group (256.1 ± 3.2 vs. 259.6 ± 5.1 h·mg/dL. Results from this study indicates that although quercetin does have blood glucose lowering potential via α-glucosidase inhibition, there are other bioactive compounds present in onion skin. Furthermore, the effects of two weeks administration of EOS in a high carbohydrate-dietary mixture (Pico 5053 on sucrase and maltase activities in intestine were evaluated in SD rat model

    15. Job strain and male fertility.

      Science.gov (United States)

      Hjollund, Niels Henrik I; Bonde, Jens Peter E; Henriksen, Tine Brink; Giwercman, Aleksander; Olsen, Jørn

      2004-01-01

      Job strain, defined as high job demands and low job control, has not previously been explored as a possible determinant of male fertility. We collected prospective data on job strain among men, and describe the associations with semen quality and probability of conceiving a clinical pregnancy during a menstrual cycle. Danish couples (N = 399) who were trying to become pregnant for the first time were followed for up to 6 menstrual periods. All men collected semen samples, and a blood sample was drawn from both partners. Job demand and job control were measured by a self-administered questionnaire at entry, and in each cycle the participants recorded changes in job control or job demand during the previous 30 days. In adjusted analyses, no associations were found between any semen characteristic or sexual hormones and any job strain variable. The odds for pregnancy were not associated with job strain. Psychologic job strain encountered in normal jobs in Denmark does not seem to affect male reproductive function.

    16. Analisis Pengaruh Lokasi, Harga, Kualitas Pendidikan dan Fasilitas Terhadap Minat dan Dampaknya Pada Keputusan Orang Tua Murid Memilih Jasa Pendidikan (Studi Pada Orang Tua Siswa di SD. High/Scope Indonesia Medan)

      OpenAIRE

      Purba, Mery Lani

      2011-01-01

      Mery Lani Purba, 2011, The Analysis of Location, Price, Education Quality, and Facilities Influence toward Interest and the Impact of Parents’ Decision to Chose Education Services (Study on Parents in SD. High/Scope Indonesia Medan), under the guidance of Prof. Dr. Paham Ginting, MS (chairman), Dr. Endang Sulistya Rini, SE, M.Si (members). SD. High/Scope Indonesia Medan is the one of international private elementary schools in Medan. SD. High/Scope Indonesia Medan is a franchise business ...

    17. Crack tip stress and strain

      International Nuclear Information System (INIS)

      Francois, D.

      1975-01-01

      The study of potential energy variations in a loaded elastic solid containing a crack leads to determination of the crack driving force G. Generalization of this concept to cases other than linear elasticity leads to definition of the integral J. In a linear solid, the crack tip stress field is characterized by a single parameter: the stress-intensity factor K. When the crack tip plastic zone size is confined to the elastic singularity J=G, it is possible to establish relationship between these parameters and plastic strain (and in particular the crack tip opening displacement delta). The stress increases because of the triaxiality effect. This overload rises with increasing strain hardening. When the plastic zone size expands, using certain hypotheses, delta can be calculated. The plastic strain intensity is exclusively dependent on parameter J [fr

    18. Management of digital eye strain.

      Science.gov (United States)

      Coles-Brennan, Chantal; Sulley, Anna; Young, Graeme

      2018-05-23

      Digital eye strain, an emerging public health issue, is a condition characterised by visual disturbance and/or ocular discomfort related to the use of digital devices and resulting from a range of stresses on the ocular environment. This review aims to provide an overview of the extensive literature on digital eye strain research with particular reference to the clinical management of symptoms. As many as 90 per cent of digital device users experience symptoms of digital eye strain. Many studies suggest that the following factors are associated with digital eye strain: uncorrected refractive error (including presbyopia), accommodative and vergence anomalies, altered blinking pattern (reduced rate and incomplete blinking), excessive exposure to intense light, closer working distance, and smaller font size. Since a symptom may be caused by one or more factors, a holistic approach should be adopted. The following management strategies have been suggested: (i) appropriate correction of refractive error, including astigmatism and presbyopia; (ii) management of vergence anomalies, with the aim of inducing or leaving a small amount of heterophoria (~1.5 Δ Exo); (iii) blinking exercise/training to maintain normal blinking pattern; (iv) use of lubricating eye drops (artificial tears) to help alleviate dry eye-related symptoms; (v) contact lenses with enhanced comfort, particularly at end-of-day and in challenging environments; (vi) prescription of colour filters in all vision correction options, especially blue light-absorbing filters; and (vii) management of accommodative anomalies. Prevention is the main strategy for management of digital eye strain, which involves: (i) ensuring an ergonomic work environment and practice (through patient education and the implementation of ergonomic workplace policies); and (ii) visual examination and eye care to treat visual disorders. Special consideration is needed for people at a high risk of digital eye strain, such as computer

    19. Taxonomy of oxalotrophic Methylobacterium strains

      Science.gov (United States)

      Sahin, Nurettin; Kato, Yuko; Yilmaz, Ferah

      2008-10-01

      Most of the oxalotrophic bacteria are facultative methylotrophs and play important ecological roles in soil fertility and cycling of elements. This study gives a detailed picture of the taxonomy and diversity of these bacteria and provides new information about the taxonomical variability within the genus Methylobacterium. Twelve mesophilic, pink-pigmented, and facultatively methylotrophic oxalate-oxidizing strains were included in this work that had been previously isolated from the soil and some plant tissues by the potassium oxalate enrichment method. The isolates were characterized using biochemical tests, cellular lipid profiles, spectral characteristics of carotenoid pigments, G+C content of the DNA, and 16S rDNA sequencing. The taxonomic similarities among the strains were analyzed using the simple matching ( S SM) and Jaccard ( S J) coefficients, and the UPGMA clustering algorithm. The phylogenetic position of the strains was inferred by the neighbor-joining method on the basis of the 16S rDNA sequences. All isolates were Gram-negative, facultatively methylotrophic, oxidase and catalase positive, and required no growth factors. Based on the results of numerical taxonomy, the strains formed four closely related clusters sharing ≥85% similarity. Analysis of the 16S rDNA sequences demonstrated that oxalotrophic, pink-pigmented, and facultatively methylotrophic strains could be identified as members of the genus Methylobacterium. Except for M. variabile and M. aquaticum, all of the Methylobacterium type strains tested had the ability of oxalate utilization. Our results indicate that the capability of oxalate utilization seems to be an uncommon trait and could be used as a valuable taxonomic criterion for differentiation of Methylobacterium species.

    20. Pengaruh Media Lagu Terhadap Hasil Belajar Matematika Pada Materi Sifat-Sifat Bangun Datar Siswa Kelas 5 SD Negeri 5 Kota Bengkulu

      Directory of Open Access Journals (Sweden)

      Myti Sandri

      2018-03-01

      Full Text Available Abstrak. Penelitian ini bertujuan  untuk mengetahui pengaruh media lagu terhadap hasil belajar matematika pada materi sifat-sifat bangun datar untuk siswa kelas 5 SD Negeri 5 Kota Bengkulu Tahun Ajaran 2015/2016 Semester II. Populasi penelitian ini adalah siswa kelas 5 SD Negeri 5 Kota Bengkulu. Sampel penelitian ini dua kelas yaitu  kelas eksperimen yang menerapkan metode ekspositori dengan menggunakan media lagu dan  kelas kontrol yang menerapkan metode ekspositori tanpa menggunakan media lagu. Teknik pengumpulan data dengan menggunakan instrumen tes. Untuk analisis data menggunakan uji-t dengan data berdistribusi normal dan homogen. Berdasarkan hasil penelitian diperoleh nilai rata-rata siswa yang diajar dengan menggunakan media lagu lebih tinggi dibandingkan dengan nilai rata-rata siswa yang diajar tanpa menggunakan media lagu. Nilai rata-rata siswa kelas eksperimen adalah 72.04 dan  nilai rata-rata siswa kelas kontrol adalah 60.21. Hal ini sesuai dengan hasil uji hipotesis nilai thitung = 1.8282 lebih dari nilai ttabel = 1.67065 dalam taraf signifikan 5%. Maka H0 ditolak sehingga dapat disimpulkan bahwa ada pengaruh media lagu terhadap hasil belajar matematika pada sifat-sifat bangun datar kelas 5 SD Negeri 5 Kota Bengkulu. Kata kunci : Hasil belajar, Media Lagu, Metode Ekspositori. Abstrak. The aim of research is knowing how to the effect of media songs on the study’s result of mathematics learning on the material of the two dimentionals characters for student class 5.C SD Negeri 5 Kota Bengkulu school of year 2015/2016 Semester II. Population of this research  is student class 5 SD Negeri 5 Kota Bengkulu. Sample of this research is student class 5.C by 31 student for the experiment class apply to expository methods to use media songs and class 5.A by 31 student for control class to apply expository method not to use media songs. The tecnich data collection is instrument test. For data analysis using t-test with normal distribution

    1. Comparative data on SD-OCT for the retinal nerve fiber layer and retinal macular thickness in a large cohort with Marfan syndrome.

      Science.gov (United States)

      Xu, WanWan; Kurup, Sudhi P; Fawzi, Amani A; Durbin, Mary K; Maumenee, Irene H; Mets, Marilyn B

      2017-01-01

      To report the distribution of macular and optic nerve topography in the eyes of individuals with Marfan syndrome aged 8-56 years using spectral domain optical coherence tomography (SD-OCT). Thirty-three patients with Marfan syndrome underwent a full eye examination including slit-lamp biomicroscopy, indirect ophthalmoscopy, and axial length measurement; and SD-OCT measurements of the retinal nerve fiber layer (RNFL) and macular thickness. For patients between the ages of 8 and 12 years, the average RNFL thickness is 98 ± 9 μm, the vertical cup to disc (C:D) ratio is 0.50 ± 0.10, the central subfield thickness (CST) is 274 ± 38 μm, and the macular volume is 10.3 ± 0.6 mm 3 . For patients between the ages of 13 and 17 years, the average RNFL is 86 ± 16 μm, the vertical C:D ratio is 0.35 ± 0.20, the CST is 259 ± 15 μm, and the macular volume is 10.1 ± 0.5 mm 3 . For patients 18 years or older, the average RNFL is 89 ± 12 μm, the vertical C:D ratio is 0.46 ± 0.18, the CST is 262 ± 20 μm, and the macular volume is 10.2 ± 0.4 mm 3 . When the average RNFL data are compared to a normative, age-adjusted database, 6 of 33 (18%) were thinner than the 5% limit. This study reports the distribution of SD-OCT data for patients with Marfan syndrome. Compared to a normative database, 18% of eyes with Marfan syndrome had RNFL thickness < 5% of the population.

    2. The diagnostic performance evaluation of the SD BIOLINE HIV/syphilis Duo rapid test in southern Ethiopia: a cross-sectional study.

      Science.gov (United States)

      Shimelis, Techalew; Tadesse, Endale

      2015-04-23

      To determine the diagnostic performance of the SD BIOLINE HIV/syphilis Duo rapid test. A hospital-based cross-sectional study. This evaluation was conducted at one of the largest hospitals in southern Ethiopia. Serum samples obtained from clients attending the antiretroviral therapy and voluntary counselling and testing centres were used. Sera were originally collected for the purpose of investigating syphilis epidemiology. The performance of the test to detect HIV was evaluated using 400 sera (200 HIV positives and 200 HIV negatives). Also, its performance to detect syphilis was evaluated using 85 syphilis positive and 100 syphilis negative serum samples. Individuals tiebreaker to determine the result. We also used ELISA to resolve discordant HIV results. Syphilis serostatus was determined using the Treponema pallidum haemagglutination assay (TPHA). The respective sensitivity, specificity, positive predictive value and negative predictive value of the SD BIOLINE HIV/syphilis Duo test were 100, 99.5, 99.5 and 100% for HIV and 97.6, 96, 95.4 and 98% for syphilis testing, respectively. In reference to TPHA, the test kit reported 4 false positives and 2 false negative results for syphilis. The κ values were 0.99 for HIV testing and 0.94 for syphilis testing. The excellent performance of the SD BIOLINE HIV/syphilis Duo test to detect HIV as well as syphilis facilitates the integration of syphilis testing and treatment to the already established HIV prevention programme, ultimately contributing to the dual HIV and syphilis elimination goal. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

    3. Theoretical study and rate constant calculation for the reactions of SH (SD) with Cl2, Br2, and BrCl.

      Science.gov (United States)

      Wang, Li; Liu, Jing-Yao; Li, Ze-Sheng; Sun, Chia-Chung

      2005-01-30

      The mechanisms of the SH (SD) radicals with Cl2 (R1), Br2 (R2), and BrCl (R3) are investigated theoretically, and the rate constants are calculated using a dual-level direct dynamics method. The optimized geometries and frequencies of the stationary points are calculated at the MP2/6-311G(d,p) and MPW1K/6-311G(d,p) levels. Higher-level energies are obtained at the approximate QCISD(T)/6-311++G(3df, 2pd) level using the MP2 geometries as well as by the multicoefficient correlation method based on QCISD (MC-QCISD) using the MPW1K geometries. Complexes with energies less than those of the reactants or products are located at the entrance or the exit channels of these reactions, which indicate that the reactions may proceed via an indirect mechanism. The enthalpies of formation for the species XSH/XSD (X = Cl and Br) are evaluated using hydrogenation working reactions method. By canonical variational transition-state theory (CVT), the rate constants of SH and SD radicals with Cl2, Br2, and BrCl are calculated over a wide temperature range of 200-2000 K at the a-QCISD(T)/6-311++G(3df, 2pd)//MP2/6-311G(d, p) level. Good agreement between the calculated and experimental rate constants is obtained in the measured temperature range. Our calculations show that for SH (SD) + BrCl reaction bromine abstraction (R3a or R3a') leading to the formation of BrSH (BrSD) + Cl in a barrierless process dominants the reaction with the branching ratios for channels 3a and 3a' of 99% at 298 K, which is quite different from the experimental result of k3a'/k3' = 54 +/- 10%. Negative activation energies are found at the higher level for the SH + Br2 and SH + BrCl (Br-abstraction) reactions; as a result, the rate constants show a slightly negative temperature dependence, which is consistent with the determination in the literature. The kinetic isotope effects for the three reactions are "inverse". The values of kH/kD are 0.88, 0.91, and 0.69 at room temperature, respectively, and they increase

    4. References for HNF-SD-WM-TRD-007, ''System specification for the double-shell tank system: HNF-PROs, CFRs, DOE Orders, WACs''

      International Nuclear Information System (INIS)

      Shaw, C.P.

      1998-01-01

      HNF-SD-WM-TRD-O07, System Specification for the Double-Shell Tank System, (hereafter referred to as DST Specification), defines the requirements of the double-shell tank system at the Hanford Site for Phase 1 privatization. Many of the sections in this document reference other documents for design guidance and requirements. Referenced documents include Project Hanford Management Contract (PHMC) procedures (HNF-PROS), Codes of Federal Regulation (CFRs), DOE Orders, and Washington Administrative Codes (WACs). This document provides rationale for the selection and inclusion of HNF-PROS, CFRs, DOE Orders and WACs

    5. Quality of life, psychosocial strains and coping in parents of children with haemophilia.

      Science.gov (United States)

      Wiedebusch, S; Pollmann, H; Siegmund, B; Muthny, F A

      2008-09-01

      Quality of life in parents of children suffering from haemophilia may be diminished by the illness burden experienced in daily life and by non-adaptive ways of coping. The aim of this study was to examine the relation between parents' quality of life, their perceived psychosocial strains and ways of coping, and to compare parents' outcome to other paediatric illness groups (juvenile idiopathic arthritis, type 1 diabetes). In a cross-sectional study, parents completed a questionnaire concerning quality of life, psychosocial strains, coping strategies and needs as well as sociodemographic and illness parameters. Study participants were recruited in an ambulant haemophilia centre. A total of 55 parents (32 mothers, 23 fathers; age = 39.6; SD = 8.6) of children suffering from haemophilia (age = 11.0; SD = 6.4) took part in the study. Comparison groups were parents of children with juvenile idiopathic arthritis (n = 161) and parents of children with type 1 diabetes (n = 69). Compared to parents from other paediatric illness groups, the parents of children with haemophilia experience less impact on their quality of life and lower psychosocial strains. Quality of life was predicted by the coping strategy 'improving marital relationship' (beta = 0.48) and by emotional strains and worries concerning future (beta = -0.43; explained variance 49%). Parents reported a pronounced need for further information on the comprehensive management of haemophilia. In the psychosocial care of families with a child suffering from -haemophilia, reducing psychosocial strains and strengthening adaptive coping strategies may be a preventive intervention for improving parents' quality of life.

    6. Noncontacting-optical-strain device

      Science.gov (United States)

      Silver, R. H.

      1970-01-01

      Noncontacting-strain-measuring gauge and extensometer remotely measures the mechanical displacement along the entire length of a test specimen. Measurement is accomplished by continuous scanning of a reflected light from reflective bench markings or stripes previously affixed to the specimen.

    7. Job strain and tobacco smoking

      DEFF Research Database (Denmark)

      Heikkilä, Katriina; Nyberg, Solja T; Fransson, Eleonor I

      2012-01-01

      Tobacco smoking is a major contributor to the public health burden and healthcare costs worldwide, but the determinants of smoking behaviours are poorly understood. We conducted a large individual-participant meta-analysis to examine the extent to which work-related stress, operationalised as job...... strain, is associated with tobacco smoking in working adults....

    8. Strain effects in oxide superconductors

      International Nuclear Information System (INIS)

      Wada, H.; Kuroda, T.; Sekine, H.; Yuyama, M.; Itoh, K.

      1991-01-01

      Strain sensitivities of superconducting properties are critical to high magnetic field applications of superconductors, since critical temperature, T c , upper critical field, H c2 , and critical current (density), I c (J c ), are all degraded under strains. Oxide superconductors so far known are all very fragile, thus requiring to be fabricated in the form of composite. In the case of practical metallic superconductors, such as Nb 3 Sn and V 3 Ga, the so-called bronze method has been developed where these superconducting intermetallics are enveloped in a ductile metallic sheath. Recently, a fabrication method similar to the bronze method has been developed for the Bi 2 Sr 2 Ca 2 Cu 3 O x superconductors using Ag tubes as sheath. In the present study mono- and multicore BiPbSrCaCuO tape conductors were prepared by means of this Ag-sheath composite method, and examined in terms of strain sensitivity by measuring their T c and I c (J c ) under bending or tensile strains. (orig.)

    9. HYDROLOGY, Grant County, SD, USA

      Data.gov (United States)

      Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a flood insurance...

    10. Mobilomics in Saccharomyces cerevisiae strains.

      Science.gov (United States)

      Menconi, Giulia; Battaglia, Giovanni; Grossi, Roberto; Pisanti, Nadia; Marangoni, Roberto

      2013-03-20

      Mobile Genetic Elements (MGEs) are selfish DNA integrated in the genomes. Their detection is mainly based on consensus-like searches by scanning the investigated genome against the sequence of an already identified MGE. Mobilomics aims at discovering all the MGEs in a genome and understanding their dynamic behavior: The data for this kind of investigation can be provided by comparative genomics of closely related organisms. The amount of data thus involved requires a strong computational effort, which should be alleviated. Our approach proposes to exploit the high similarity among homologous chromosomes of different strains of the same species, following a progressive comparative genomics philosophy. We introduce a software tool based on our new fast algorithm, called regender, which is able to identify the conserved regions between chromosomes. Our case study is represented by a unique recently available dataset of 39 different strains of S.cerevisiae, which regender is able to compare in few minutes. By exploring the non-conserved regions, where MGEs are mainly retrotransposons called Tys, and marking the candidate Tys based on their length, we are able to locate a priori and automatically all the already known Tys and map all the putative Tys in all the strains. The remaining putative mobile elements (PMEs) emerging from this intra-specific comparison are sharp markers of inter-specific evolution: indeed, many events of non-conservation among different yeast strains correspond to PMEs. A clustering based on the presence/absence of the candidate Tys in the strains suggests an evolutionary interconnection that is very similar to classic phylogenetic trees based on SNPs analysis, even though it is computed without using phylogenetic information. The case study indicates that the proposed methodology brings two major advantages: (a) it does not require any template sequence for the wanted MGEs and (b) it can be applied to infer MGEs also for low coverage genomes

    11. Mobilomics in Saccharomyces cerevisiae strains

      Science.gov (United States)

      2013-01-01

      Background Mobile Genetic Elements (MGEs) are selfish DNA integrated in the genomes. Their detection is mainly based on consensus–like searches by scanning the investigated genome against the sequence of an already identified MGE. Mobilomics aims at discovering all the MGEs in a genome and understanding their dynamic behavior: The data for this kind of investigation can be provided by comparative genomics of closely related organisms. The amount of data thus involved requires a strong computational effort, which should be alleviated. Results Our approach proposes to exploit the high similarity among homologous chromosomes of different strains of the same species, following a progressive comparative genomics philosophy. We introduce a software tool based on our new fast algorithm, called regender, which is able to identify the conserved regions between chromosomes. Our case study is represented by a unique recently available dataset of 39 different strains of S.cerevisiae, which regender is able to compare in few minutes. By exploring the non–conserved regions, where MGEs are mainly retrotransposons called Tys, and marking the candidate Tys based on their length, we are able to locate a priori and automatically all the already known Tys and map all the putative Tys in all the strains. The remaining putative mobile elements (PMEs) emerging from this intra–specific comparison are sharp markers of inter–specific evolution: indeed, many events of non–conservation among different yeast strains correspond to PMEs. A clustering based on the presence/absence of the candidate Tys in the strains suggests an evolutionary interconnection that is very similar to classic phylogenetic trees based on SNPs analysis, even though it is computed without using phylogenetic information. Conclusions The case study indicates that the proposed methodology brings two major advantages: (a) it does not require any template sequence for the wanted MGEs and (b) it can be applied to

    12. Primary visual cortex in neandertals as revealed from the occipital remains from the El Sidrón site, with emphasis on the new SD-2300 specimen.

      Science.gov (United States)

      García-Tabernero, Antonio; Peña-Melián, Angel; Rosas, Antonio

      2018-07-01

      The comparative analysis of the endocranial surface of the El Sidrón new occipital fragment SD-2300 shows meaningful differences in the configuration of the occipital pole region between neandertals and anatomically modern humans (AMH). The particular asymmetries found in neandertals in the venous sinus drainage and the petalial patterns are recognizable in this new specimen as well. In addition, the supra- and infracalcarine fossae of the occipital pole region appear to deviate obliquely from the mid-line when compared with sapiens. Due to the excellent preservation conditions of SD-2300, the main sulci and gyri of the occipital pole area have been identified, this degree of detail being uncommon in a fossil specimen; in general, the gyrification pattern is similar to AMH, but with some notable differences. Particularly interesting is the description of the lunate and the calcarine sulci. The lunate sulcus is located close to the occipital pole, in a similar posterior position to in other Homo species. Regarding the calcarine sulcus, there are significant differences in the primary visual cortex, with the V1 area, or Brodmann area 17, being larger in Homo neanderthalensis than in Homo sapiens. This may lead to greater visual acuity in neandertals than in sapiens. © 2018 Anatomical Society.

    13. THE ROMER DELAY AND MASS RATIO OF THE sdB+dM BINARY 2M 1938+4603 FROM KEPLER ECLIPSE TIMINGS

      Energy Technology Data Exchange (ETDEWEB)

      Barlow, Brad N.; Wade, Richard A.; Liss, Sandra E. [Department of Astronomy and Astrophysics, 525 Davey Lab, Pennsylvania State University, University Park, PA 16802 (United States)

      2012-07-10

      The eclipsing binary system 2M 1938+4603 consists of a pulsating hot subdwarf B star and a cool M dwarf companion in an effectively circular three-hour orbit. The light curve shows both primary and secondary eclipses, along with a strong reflection effect from the cool companion. Here, we present constraints on the component masses and eccentricity derived from the Romer delay of the secondary eclipse. Using six months of publicly available Kepler photometry obtained in short-cadence mode, we fit model profiles to the primary and secondary eclipses to measure their centroid values. We find that the secondary eclipse arrives on average 2.06 {+-} 0.12 s after the midpoint between primary eclipses. Under the assumption of a circular orbit, we calculate from this time delay a mass ratio of q = 0.2691 {+-} 0.0018 and individual masses of M{sub sd} = 0.372 {+-} 0.024 M{sub Sun} and M{sub c} = 0.1002 {+-} 0.0065 M{sub Sun} for the sdB and M dwarf, respectively. These results differ slightly from those of a previously published light-curve modeling solution; this difference, however, may be reconciled with a very small eccentricity, ecos {omega} Almost-Equal-To 0.00004. We also report a decrease in the orbital period of P-dot = (-1.23 {+-} 0.07) Multiplication-Sign 10{sup -10}.

    14. Single oral dose toxicity test of polycalcium, a mixed composition of polycan and calcium lactate-gluconate 1:9 (G/G) in SD rat.

      Science.gov (United States)

      Kim, Joo-Wan; Choi, Jae-Suk; Ha, Yu-Mi; Choi, In Soon; Kim, Ki-Young; Cho, Hyung-rae; Rha, Chae-hun; Ku, Sae-Kwang

      2013-11-01

      The object of this study was to obtain acute oral toxicity information of Polycalcium, a mixed composition of Polycan and Calcium lactate-gluconate 1:9 (g/g), in Sprague-Dawely (SD) rats. In order to investigate the toxicity and identify target organs, Polycalcium were once orally administered to female and male SD rats at dose levels of 2000, 1000, 500 and 0 (control) mg/kg body weights. The mortality, changes on body weight and clinical signs were monitored during 14 days after treatment with gross observation, changes on the organ weights and histopathology of principle organs and treatment sites based on the recommendation of KFDA Guidelines [2009-116, 2009]. As the results of single oral treatment of Polycalcium, no treatment related mortalities were observed within 14 days after end of treatment up to 2000 mg/kg, the limited dosage of rodents in the both genders. In addition, no Polycalcium treatment related changes on the body and organ weights, clinical signs, necropsy and histopathological findings were detected. The results obtained in this study suggest that the Polycalcium is non-toxic in rats. The LD50 and approximate LD in rats after single oral dose of Polycalcium were considered over 2000 mg/kg in both female and male, respectively.

    15. A NEW STRAIN OF TRANSMISSIBLE LEUCEMIA IN FOWLS (STRAIN H).

      Science.gov (United States)

      Ellermann, V

      1921-03-31

      1. A new strain of fowl leucosis has been transmitted through twelve generations of fowls. 2. An increase in virulence was observed during its passage. This was shown in a shortening of the interval between inoculation and death. The increase in virulence does not affect the number of successful inoculations, which remains approximately constant in from 20 to 40 per cent of the birds employed. 3. As with former strains, the disease manifests itself in various forms; i.e., myeloid and intravascular lymphoid types. A single lymphatic case was observed. 4. In several intravascular cases a diminution in the hemolytic power of the serum was established. This phenomenon was absent in a number of myeloid cases. 5. Active immunization cannot be produced by means of the subcutaneous injection of virulent material. 6. The finding of previous experiments that the virus is filterable has been confirmed. 7. The inoculation of human leucemic material into fowls gave negative results.

    16. Probiotic properties of Lactobacillus strains isolated from Tibetan kefir grains.

      Directory of Open Access Journals (Sweden)

      Yongchen Zheng

      Full Text Available The objective of this study was to evaluate the functional properties of lactic acid bacteria (LAB isolated from Tibetan kefir grains. Three Lactobacillus isolates identified as Lactobacillus acidophilus LA15, Lactobacillus plantarum B23 and Lactobacillus kefiri D17 that showed resistance to acid and bile salts were selected for further evaluation of their probiotic properties. The 3 selected strains expressed high in vitro adherence to Caco-2 cells. They were sensitive to gentamicin, erythromycin and chloramphenicol and resistant to vancomycin with MIC values of 26 µg/ml. All 3 strains showed potential bile salt hydrolase (BSH activity, cholesterol assimilation and cholesterol co-precipitation ability. Additionally, the potential effect of these strains on plasma cholesterol levels was evaluated in Sprague-Dawley (SD rats. Rats in 4 treatment groups were fed the following experimental diets for 4 weeks: a high-cholesterol diet, a high-cholesterol diet plus LA15, a high-cholesterol diet plus B23 or a high-cholesterol diet plus D17. The total cholesterol, triglyceride and low-density lipoprotein cholesterol levels in the serum were significantly (P<0.05 decreased in the LAB-treated rats compared with rats fed a high-cholesterol diet without LAB supplementation. The high-density lipoprotein cholesterol levels in groups B23 and D17 were significantly (P<0.05 higher than those in the control and LA15 groups. Additionally, both fecal cholesterol and bile acid levels were significantly (P<0.05 increased after LAB administration. Fecal lactobacilli counts were significantly (P<0.05 higher in the LAB treatment groups than in the control groups. Furthermore, the 3 strains were detected in the rat small intestine, colon and feces during the feeding trial. The bacteria levels remained high even after the LAB administration had been stopped for 2 weeks. These results suggest that these strains may be used in the future as probiotic starter cultures for

    17. Tersane Yatırımları İçin Kuruluş Yeri Seçimi: Yalova-Altınova Tersane Girişimcileri Sanayi ve Ticaret Anonim Şirketi Örneği

      Directory of Open Access Journals (Sweden)

      Yeşim ALİEFENDİOĞLU

      2015-06-01

      Full Text Available Bu çalışmada, emek yoğun sektör olması ve birçok sanayi dalı ile etkileşim içinde olması sebebiyle yüksek istihdam olanağı sağlayan, yüksek katma değerli ürünleri ile ihracatta önemli katkı yapan, ülke ekonomisine döviz geliri sağlayan ve savunma sanayiine katkısı ile teknolojik altyapının gelişmesine olanak sağlayan gemi inşa sektöründe kuruluş yeri seçimi hem genel, hem de seçilmiş örnek olay düzeyinde irdelenmiştir. Tersane proje geliştiricisi ve yöneticileri yönünden kuruluş yeri seçim kriterleri değerlendirildiğinde; coğrafi konum, ulaşım olanakları, gemi sanayinin varlığı, gemi inşa yan sanayinin varlığı, devlet teşviki, toplam ve nitelikli işgücü varlığı, jeolojik durum, topografik yapı, enerji kaynaklarının yeterliliği, altyapı yatırımları, kıyı kesiminin özelliği, dalga etkisi, rüzgar etkisi, diğer tersane bölgelerine uzaklığı, bölgenin sosyo-kültürel yapısı, havalimanına yakınlığı, stratejik durumu, hammaddeye yakınlığı, öz kaynakların ve ilave tesis alanlarının önemi, arazi ve arsa varlığı, su kaynaklarının varlığı ve konaklama tesislerinin varlığı gibi parametrelerin önemli olduğu ortaya konulmuştur. Kuruluş yeri seçiminde tersane kuruluşunu gerektirecek iş hacminin tespiti ile tersane kuruluş yerinin uluslararası kriterlere uygunluğu parametrelerinin de önem taşıdığı sonucuna ulaşılmıştır. Örnek olay olarak incelenen Yalova-Altınova Tersaneler Bölgesi ve seçilen tesisin yer seçiminin, belirtilen kuruluş yeri seçim kriterlerine uygun olduğu görülmektedir. Tersane yatırımlarının geliştirilmesi ve özellikle gemi sanayinde üretim ve ihracat kapasitesinin geliştirilmesi bakımından bütün kıyı yerleşimlerinde tersane kuruluş yeri seçimi ve fiilen yatırıma başlanmasına yönelik master plan hazırlanması ve buna göre yatırımların ulusal ve bölgesel düzeylerde y

    18. Arte, criatividade e desenvolvimento socioemocional de alunos com altas habilidades/ superdotação (AH/SD: considerações a partir de Vigotski

      Directory of Open Access Journals (Sweden)

      Cristiana Lopes Machado

      2017-08-01

      Full Text Available A educação de alunos com altas habilidades/superdotação (AH/SD é assegurada pela legislação em vigor que admite esse discente como sujeito de direito à educação especial (BRASIL, 1996; VIRGOLIM, 2012; PISKE, 2014b. Contudo, mesmo a educação especial constituindo-se como um direito, muitos desses alunos encontram-se em situação de exclusão escolar (FREITAS; REICH, 2015. Diante disso, o objetivo do presente estudo é investigar as implicações da arte e da criatividade para o desenvolvimento socioemocional de alunos com AH/SD no contexto inclusivo. Essa investigação se justifica na medida em que procura explicitar o potencial educativo das atividades artísticas e criativas. Este estudo possui caráter qualitativo e é de natureza exploratória. Para tanto, adotamos como instrumentos de coleta de dados a entrevista semiestruturada e a observação. Os participantes desse estudo foram 10 alunos identificados com AH/SD, estudantes da rede de ensino de um município no Estado do Paraná e frequentadores de Sala de Recursos Multifuncional. A partir da análise dos dados, baseada em Aguiar e Ozella (2006, foi possível perceber que a arte e a criatividade constituem-se como instrumentos que auxiliam esse discente a lidar com seu mundo interior, como também possibilitam oportunidades para o emprego do potencial criativo e inovador. Nesse sentido, o estudo aponta para a necessidade de revisão das práticas pedagógicas destinadas aos discentes com potencial superior, como também para a investigação de metodologias de ensino que integrem as atividades artísticas e criativas em suas práticas educacionais.

    19. The quest for stable circumbinary companions to post-common envelope sdB eclipsing binaries. Does the observational evidence support their existence?

      Science.gov (United States)

      Pulley, D.; Faillace, G.; Smith, D.; Watkins, A.; von Harrach, S.

      2018-03-01

      Context. Period variations have been detected in a number of eclipsing close compact binary subdwarf B stars (sdBs) and these have often been interpreted as being caused by circumbinary massive planets or brown dwarfs. According to canonical binary models, the majority of sdB systems are produced from low mass stars with degenerate cores where helium is ignited in flashes. Various evolutionary scenarios have been proposed for these stars, but a definite mechanism remains to be established. Equally puzzling is the formation of these putative circumbinary objects which must have formed from the remaining post-common envelope circumbinary disk or survived its evolution. Aim. In this paper we review the eclipse time variations (ETVs) exhibited by seven such systems (EC 10246-2707, HS 0705+6700, HS 2231+2441, J08205+0008, NSVS 07826147, NSVS 14256825, and NY Vir) and explore whether there is conclusive evidence that the ETVs observed over the last two decades can reliably predict the presence of one or more circumbinary bodies. Methods: We report 246 new observations of the seven sdB systems made between 2013 September and 2017 July using a worldwide network of telescopes. We combined our new data with previously published measurements to analyse the ETVs of these systems. Results: Our data show that period variations cannot be modelled simply on the basis of circumbinary objects. This implies that more complex processes may be taking place in these systems. These difficulties are compounded by the secondary star not being spectroscopically visible. From ETVs, it has historically been suggested that five of the seven binary systems reported here had circumbinary objects. Based on our recent observations and analysis, only three systems remain serious contenders. We find agreement with other observers that at least a decade of observations is required to establish reliable ephemerides. With longer observational baselines it is quite conceivable that the data will support

    20. Studies on the toxic effects of periodontal sustained release drug containing ornidazole and pefloxacin mesylate on early embryonic development of SD rat

      Directory of Open Access Journals (Sweden)

      Zheng-mou DONG

      2011-01-01

      Full Text Available Objective To evaluate the toxic effects of periodontal sustained release drug containing ornidazole and pefloxacin mesylate on early embryonic development of SD rats.Methods A total of 100female SD rats were randomly divided into negative control,low-,medium-,high-dose group and intervention group(20each.Rats in low-,medium-and high-dose group were fed daily with the sustained release drug at 1,4,and 8g/kg respectively;those in negative control group were fed daily with distilled water from the 14th day before mating to the 7th day of pregnancy continuously,and those in intervention group received cyclophosphamide(40mg/kgby intraperitoneal injection for 5successive days.During this period,the general status,mating,pregnancy,coefficient of ovary and uterus,the numbers of corpus luteum,nidation,live births,stillbirths,absorbed embryo,prenidatory and postnidatory mortality,serum testosterone(Tand estradiol(E2were determined respectively.Histopathologic examination of the ovary and uterus,immunohistochemical observation of ovaries for proliferating cell nuclear antigen(PCNAand Bcl-2associated X protein(Baxwere also performed respectively.Results The general status of those rats was good except one in the low-dose group and one in the intervention group died on the 14th day of administration,and one in negative control and one in high dose group died on the 5th day of pregnancy,respectively.The body weight of animals decreased significantly(P 0.05.The serum T level in medium-and high-dose group and the E2level in high-dose group declined compared to that in negative control group(P < 0.05.Conclusions Although the periodontal sustained release drug containing ornidazole and pefloxacin mesylate shows no toxicity to the early embryonic development of SD rats,the high dose drug has certain toxicity to ovary.Declined serum concentrations of T and E2,reduced expression of PCNA,and increased Bax may be the causes of the toxicity.

    1. Computational strain gradient crystal plasticity

      DEFF Research Database (Denmark)

      Niordson, Christian Frithiof; Kysar, Jeffrey W.

      2014-01-01

      A numerical method for viscous strain gradient crystal plasticity theory is presented, which incorporates both energetic and dissipative gradient effects. The underlying minimum principles are discussed as well as convergence properties of the proposed finite element procedure. Three problems...... of plane crystal plasticity are studied: pure shear of a single crystal between rigid platens as well as plastic deformation around cylindrical voids in hexagonal close packed and face centered cubic crystals. Effective in-plane constitutive slip parameters for plane strain deformation of specifically...... oriented face centered cubic crystals are developed in terms of the crystallographic slip parameters. The effect on geometrically necessary dislocation structures introduced by plastic deformation is investigated as a function of the ratio of void radius to plasticity length scale....

    2. Strain-Detecting Composite Materials

      Science.gov (United States)

      Wallace, Terryl A. (Inventor); Smith, Stephen W. (Inventor); Piascik, Robert S. (Inventor); Horne, Michael R. (Inventor); Messick, Peter L. (Inventor); Alexa, Joel A. (Inventor); Glaessgen, Edward H. (Inventor); Hailer, Benjamin T. (Inventor)

      2016-01-01

      A composite material includes a structural material and a shape-memory alloy embedded in the structural material. The shape-memory alloy changes crystallographic phase from austenite to martensite in response to a predefined critical macroscopic average strain of the composite material. In a second embodiment, the composite material includes a plurality of particles of a ferromagnetic shape-memory alloy embedded in the structural material. The ferromagnetic shape-memory alloy changes crystallographic phase from austenite to martensite and changes magnetic phase in response to the predefined critical macroscopic average strain of the composite material. A method of forming a composite material for sensing the predefined critical macroscopic average strain includes providing the shape-memory alloy having an austenite crystallographic phase, changing a size and shape of the shape-memory alloy to thereby form a plurality of particles, and combining the structural material and the particles at a temperature of from about 100-700.degree. C. to form the composite material.

    3. PENGEMBANGAN MODUL PEMBELAJARAN SAINS BERBASIS INTEGRASI ISLAM-SAINS UNTUK PESERTA DIDIK DIFABEL NETRA MI/SD KELAS 5 SEMESTER 2 MATERI POKOK BUMI DAN ALAM SEMESTA

      Directory of Open Access Journals (Sweden)

      F. Yuliawati

      2013-10-01

      Full Text Available Tujuan penelitian untuk menghasilkan modul pembelajaran sains Madrasah Ibtidaiyah untuk peserta didik difabel netra berbasis integrasi Islam-sains yang memiliki karakter tertentu. Penelitian ini merupakan penelitian pengembangan. Modul pembelajaran yang telah dikembangkan mendapatkan penilaian baik menurut penilaian ahli media, pendidik SD dan SLB, dengan persentase keidealan 74,31%. Berdasarkan hal tersebut, modul Braille ini layak digunakan peserta didik sebagai media belajar mandiri dalam melaksanakan pembelajaran sains. For research purposes is to produce science learning modules Madrasah Ibtidaiyah for learners with disabilities blind Islam-science-based integration with certain characteristics. This research is development research. Learning modules that have been developed to get good ratings according to media expert assessment, elementary and special educators, with a percentage of 74.31% ideals. Based on this, the Braille module learners fit for use as a medium of self study in implementing science lessons.

    4. Correlação entre a Autofluorescência de Fundo e o SD-OCT na Degenerescência Macular Ligada à Idade Exsudativa

      OpenAIRE

      Miranda, Ana Filipa

      2016-01-01

      Introdução: Estudos têm mostrado que na degenerescência macular ligada à idade (DMLI) exsudativa uma maior área de alteração do epitélio pigmentar retiniano (EPR) na autofluorescência de fundo (FAF) está associada a perda da acuidade visual (AV). Não existe, no entanto, nenhum estudo realizado nestes doentes que integre as alterações verificadas na FAF com a informação anatómica da tomografia de coerência óptica spectral domain (SD-OCT). Objectivo: Investigar a correlação entre a FAF e os res...

    5. [Effect of total flavones from Cuscuta chinensis on expression of Fas/FasL, PCNA and HB-EGF in SD rats model with bromocriptine-induced abortion].

      Science.gov (United States)

      Ma, Hong-Xia; You, Zhao-Ling; Wang, Xiao-Yun

      2008-11-01

      To explore the effect of total flavones from cuscuta chinensis (TFCC) on expression of Fas, PCNA and HB-EGF in SD rats model with bromocriptine-induced abortion. The model rats of bromocriptine during 6-8 d of pregnancy induced early abortion was established, adopting respectively herbs in high and low dosage and progesterone affect model rat and after 12 d, Immunohistochemical was applied to determine Fas, HB-EGF and PCNA in deciduas and placenta. Expression of PCNA on trophoblast and deciduas, HB-EGF on trophoblast, PR on deciduas in the model used Semen cuscutae flavonoid, proesterone and normal pregnacy, were significantlly higher than those of the pure model. Expression of Fas on trophoblast and deciduas in above four groups, were significantlly lower than those of the pure model. There were no expression of HB-EGF on deciduas. TFCC regulates the proliferation and apoptosis of the deciduas and cytotrophoblasts and prevents spontaneous abortions.

    6. Penerapan Metode Think Pair Share untuk Meningkatkan Prestasi Belajar Materi Peran Serta dalam Pemilihan Organisasi di Sekolah pada Siswa Kelas V SD

      Directory of Open Access Journals (Sweden)

      Mestiyah

      2018-02-01

      Full Text Available Berdasarkan hasil observasi yang dilakukan di Kelas VA pada waktu pembelajaran Pendidikan Kewarganegaraan diperoleh hasil bahwa Prestasi belajar siswa kurang memuaskan, yaitu dari 24 siswa hanya 10 siswa yang nilainya dapat mencapai KKM atau ≥ 70, sedangkan 14 siswa lainnya masih belum dapat mencapai KKM atau ≤ 69. Hal ini disebabkan karena guru kurang memberikan penekanan materi yang jelas tentang Peran serta dalam pemilihan organisasi di sekolah. Untuk itu agar dapat meningkatkan prestasi belajar siswa dalam menyelesaikan soal tentang Peran serta dalam pemilihan organisasi di sekolah serta untuk tercapainya tujuan pembelajaran perlu diadakan perbaikan pembelajaran dengan menerapkan Metode Think Pair Share. Penerapan pembelajaran Peran serta dalam pemilihan organisasi di sekolah melalui Metode Think Pair Share dapat meningkatkan Prestasi belajar siswa Kelas VA SD Negeri 2 Banyuurip Kalidawir Tulungagung

    7. Mechanical properties of fractures from drillholes, UE25-NRG-4; USW-NRG-6; USW-NRG-7; USW-SD-9, at Yucca Mountain, Nevada

      International Nuclear Information System (INIS)

      Olsson, W.A.; Brown, S.R.

      1997-01-01

      Rock cores from drillholes UE25-NRG-4, USW-NRG-6, USW-NRG-7, and USW-SD-9 containing natural fractures were obtained from the Sample Management Facility at Yucca Mountain, Nevada. All recoverable fractures were sheared at constant normal stresses from 2.5 to 15 MPa, in the as-received condition (air-dry). Detailed profilometer data were collected from each fracture surface before testing. The tests yielded the normal closure as a function of normal stress, and the shear stress and dilation as functions of shear offset. The constitutive properties obtained from these stress-displacement relations were: normal stiffness, shear stiffness, shear strength, and dilation angle at peak shear stress. Shear strength plotted against normal stress for four thermomechanical units shows that friction angle varies from 370 to 460 and cohesion varies from 0.02 to 1.71 MPa

    8. Nutrient content of sorghum beer strainings

      African Journals Online (AJOL)

      Sorghum beer strainings were analysed for starch, protein, fat, crude fibre, ash, minerals and ... The importance of minerals in animal nutrition has been recognized for many ..... strainings is probably due to yeast activity during fermentation ...

    9. Gangguan Perhatian/ Inatensi pada Anak (Studi Kasus pada Siswa Kelas Bawah di SD IT Cahaya Bangsa Semarang pada Tahun Ajaran (2014/2015

      Directory of Open Access Journals (Sweden)

      Fitri Kusuma Sari

      2015-04-01

      Full Text Available Gangguan perhatian sangat mengganggu perkembangan anak dalam aspek sosial, belajar dan pribadi. Faktor keluarga memiliki pengaruh yang sangat tinggi terhadap perkembangan gangguan perhatian pada anak. Sehingga penelitian ini ingin mengetahui tingkat gangguan perhatian dan pengaruh faktor keluarga terhadap gangguan perhatian yang dialami anak. Sejalan dengan tujuan dari penelitian ini untuk mengetahui tingkat gangguan perhatian dan pengaruh faktor keluarga pada siswa kelas bawah SD IT Cahaya Bangsa Semarang. Skala penilaian digunakan untuk mengukur tingkat gangguan perhatian keempat subjek dan wawancara diberikan kepada subjek, wali kelas, teman dan orang tua subjek untuk memperoleh data pengaruh faktor keluarga. Analisis data menggunakan analisis deskriptif presentase dan analisis deskriptif studi kasus. Ditemukan bahwa tingkat gangguan perhatian pada keempat subjek tinggi dan faktor keluarga sangat mempengaruhinya. Faktor keluarga yang sangat berpengaruh adalah pola asuh orang tua yang cenderung kepada pola asuh permisif dan pola asuh otoriter. Inattention is very disturbing of child development in sosial, learning and personal aspect. Family factors have a very high influence on the development of inattention in children. Therefore, this research would like to know the level of inattention and the influence of femily factors on inattention experienced by children. In line with the objectives of this study to determine the level of inattention and the influence of family factors on the lower grade student SD IT Cahaya Bangsa Semarang. Rating scale used to measure the level of the fourth subject of inattention and interviews given to the subject,homeroom, friends and the parents to obtain the data subject influence of family factors. Data analysis using descriptive analysis and the percentage of descriptive analysis of case studies. It was found that the level of inattention in the fourth subject is very high and the family factors is

    10. Senam Otak (Brain Gym Berpengaruh Terhadap Tingkat Stres pada Anak Usia Sekolah Kelas V di SD Negeri Pokoh 1 Wedomartani Ngemplak Sleman Yogyakarta

      Directory of Open Access Journals (Sweden)

      Yunita Dikir

      2016-07-01

      Full Text Available Learning activities may cause excessive stress IN children. 82.8% of the causes of stress in children in Indonesian are from their very tight routine. Data of the National Commission for Children Protection show an average of 200 cases per month which increases 28%. Brain gym is used as one of the activities to address the issue of stress in children and to improve memory. This research is aimed at identifying the effect of brain gym on stress levels in school-age children of fifth grade at SD Negeri Pokoh 1 Wedomartani Ngemplak Sleman Yogyakarta. This research is a quasi-experimental research with one-group pre and post-test design. The subjects of the research were all fifth grade students at SD Negeri Pokoh 1 Wedomartani Ngemplak Sleman Yogyakarta in 2014, numbering 36 students. Sampling employed a total sampling and data were analyzed using the wilcoxon test. The results showed that the stress level of children before the brain gym given was mostly in the moderate category (50.0% and after the brain gym given was mostly in the normal category (75.0%. The statistical test using the wilcoxon test generated p-value of 0.000 <0.05. Conclusion, there was a significant effect of brain gym on stress levels before and after treatment in the fifth grade students at SD Negeri Pokoh 1 Wedomartani Ngemplak Sleman Yogyakarta.

    11. ELECTRON-CAPTURE AND β-DECAY RATES FOR sd-SHELL NUCLEI IN STELLAR ENVIRONMENTS RELEVANT TO HIGH-DENSITY O–NE–MG CORES

      Energy Technology Data Exchange (ETDEWEB)

      Suzuki, Toshio [Department of Physics and Graduate School of Integrated Basic Sciences, College of Humanities and Sciences, Nihon University Sakurajosui 3-25-40, Setagaya-ku, Tokyo 156-8550 (Japan); Toki, Hiroshi [Research Center for Nuclear Physics (RCNP), Osaka University, Ibaraki, Osaka 567-0047 (Japan); Nomoto, Ken’ichi, E-mail: suzuki@phys.chs.nihon-u.ac.jp [Kavli Institute for the Physics and Mathematics of the Universe (WPI), The University of Tokyo, Kashiwa, Chiba 277-8583 (Japan)

      2016-02-01

      Electron-capture and β-decay rates for nuclear pairs in the sd-shell are evaluated at high densities and high temperatures relevant to the final evolution of electron-degenerate O–Ne–Mg cores of stars with initial masses of 8–10 M{sub ⊙}. Electron capture induces a rapid contraction of the electron-degenerate O–Ne–Mg core. The outcome of rapid contraction depends on the evolutionary changes in the central density and temperature, which are determined by the competing processes of contraction, cooling, and heating. The fate of the stars is determined by these competitions, whether they end up with electron-capture supernovae or Fe core-collapse supernovae. Since the competing processes are induced by electron capture and β-decay, the accurate weak rates are crucially important. The rates are obtained for pairs with A = 20, 23, 24, 25, and 27 by shell-model calculations in the sd-shell with the USDB Hamiltonian. Effects of Coulomb corrections on the rates are evaluated. The rates for pairs with A = 23 and 25 are important for nuclear Urca processes that determine the cooling rate of the O–Ne–Mg core, while those for pairs with A = 20 and 24 are important for the core contraction and heat generation rates in the core. We provide these nuclear rates at stellar environments in tables with fine enough meshes at various densities and temperatures for studies of astrophysical processes sensitive to the rates. In particular, the accurate rate tables are crucially important for the final fates of not only O–Ne–Mg cores but also a wider range of stars, such as C–O cores of lower-mass stars.

    12. ELECTRON-CAPTURE AND β-DECAY RATES FOR sd-SHELL NUCLEI IN STELLAR ENVIRONMENTS RELEVANT TO HIGH-DENSITY O–NE–MG CORES

      International Nuclear Information System (INIS)

      Suzuki, Toshio; Toki, Hiroshi; Nomoto, Ken’ichi

      2016-01-01

      Electron-capture and β-decay rates for nuclear pairs in the sd-shell are evaluated at high densities and high temperatures relevant to the final evolution of electron-degenerate O–Ne–Mg cores of stars with initial masses of 8–10 M ⊙ . Electron capture induces a rapid contraction of the electron-degenerate O–Ne–Mg core. The outcome of rapid contraction depends on the evolutionary changes in the central density and temperature, which are determined by the competing processes of contraction, cooling, and heating. The fate of the stars is determined by these competitions, whether they end up with electron-capture supernovae or Fe core-collapse supernovae. Since the competing processes are induced by electron capture and β-decay, the accurate weak rates are crucially important. The rates are obtained for pairs with A = 20, 23, 24, 25, and 27 by shell-model calculations in the sd-shell with the USDB Hamiltonian. Effects of Coulomb corrections on the rates are evaluated. The rates for pairs with A = 23 and 25 are important for nuclear Urca processes that determine the cooling rate of the O–Ne–Mg core, while those for pairs with A = 20 and 24 are important for the core contraction and heat generation rates in the core. We provide these nuclear rates at stellar environments in tables with fine enough meshes at various densities and temperatures for studies of astrophysical processes sensitive to the rates. In particular, the accurate rate tables are crucially important for the final fates of not only O–Ne–Mg cores but also a wider range of stars, such as C–O cores of lower-mass stars

    13. Selection and Validation of Reference Genes for Quantitative Real-Time PCR Normalization Under Ethanol Stress Conditions in Oenococcus oeni SD-2a

      Directory of Open Access Journals (Sweden)

      Shuai Peng

      2018-05-01

      Full Text Available The powerful Quantitative real-time PCR (RT-qPCR was widely used to assess gene expression levels, which requires the optimal reference genes used for normalization. Oenococcus oeni (O. oeni, as the one of most important microorganisms in wine industry and the most resistant lactic acid bacteria (LAB species to ethanol, has not been investigated regarding the selection of stable reference genes for RT-qPCR normalization under ethanol stress conditions. In this study, nine candidate reference genes (proC, dnaG, rpoA, ldhD, ddlA, rrs, gyrA, gyrB, and dpoIII were analyzed to determine the most stable reference genes for RT-qPCR in O. oeni SD-2a under different ethanol stress conditions (8, 12, and 16% (v/v ethanol. The transcript stabilities of these genes were evaluated using the algorithms geNorm, NormFinder, and BestKeeper. The results showed that dnaG and dpoIII were selected as the best reference genes across all experimental ethanol conditions. Considering single stress experimental modes, dpoIII and dnaG would be suitable to normalize expression level for 8% ethanol shock treatment, while the combination of gyrA, gyrB, and rrs would be suitable for 12% ethanol shock treatment. proC and gyrB revealed the most stable expression in 16% ethanol shock treatment. This study selected and validated for the first time the reference genes for RT-qPCR normalization in O. oeni SD-2a under ethanol stress conditions.

    14. Evaluating plantar fascia strain in hyperpronating cadaveric feet following an extra-osseous talotarsal stabilization procedure.

      Science.gov (United States)

      Graham, Michael E; Jawrani, Nikhil T; Goel, Vijay K

      2011-01-01

      Abnormal talotarsal joint mechanics leading to hyperpronation is implicated as one of the most common causes of plantar fasciopathy. In patients with hyperpronating feet, the plantar fascia experiences excessive tensile forces during static and dynamic weight-bearing activities because of excessive medial longitudinal arch depression. For the purposes of this study, we hypothesized that plantar fascia strain in hyperpronating cadaveric feet would decrease after intervention with an extra-osseous talotarsal stabilization (EOTTS) device. A miniature differential variable reluctance transducer was used to quantify the plantar fascia strain in 6 fresh-frozen cadaver foot specimens exhibiting flexible instability of the talotarsal joint complex (i.e., hyperpronation). The strain was measured as the foot was moved from its neutral to maximally pronated position, before and after intervention using the HyProCure(®) EOTTS device. The mean plantar fascia elongation was 0.83 ± 0.27 mm (strain 3.62% ± 1.17%) and 0.56 ± 0.2 mm (strain 2.42% ± 0.88%) before and after intervention, respectively (N = 18, variation reported is ± 1 SD). The average plantar fascia strain decreased by 33%, and the difference was statistically significant with p plantar fascia strain suggests that an EOTTS device might be effective in stabilizing the pathologic talotarsal joint complex and the medial longitudinal arch and in eliminating hyperpronation. An EOTTS procedure might offer a possible treatment option for plantar fasciopathy in cases in which the underlying etiology is abnormal talotarsal biomechanics. Copyright © 2011 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

    15. Yeast strains and methods of use thereof

      OpenAIRE

      Goddard, Matthew Robert; Gardner, Richard Clague; Anfang, Nicole

      2013-01-01

      The present invention relates to yeast strains and, in particular, to yeast stains for use in fermentation processes. The invention also relates to methods of fermentation using the yeast strains of the invention either alone or in combination with other yeast strains. The invention thither relates to methods for the selection of yeast strains suitable for fermentation cultures by screening for various metabolic products and the use of specific nutrient sources.

    16. Development of Industrial Yeast Platform Strains

      DEFF Research Database (Denmark)

      Bergdahl, Basti; Dato, Laura; Förster, Jochen

      2014-01-01

      Most of the current metabolic engineering projects are carried out using laboratory strains as the starting host. Although such strains are easily manipulated genetically, their robustness does not always meet the requirements set by industrial fermentation conditions. In such conditions, the cells...... screening of the 36 industrial and laboratory yeast strains. In addition, progress in the development of molecular biology methods for generating the new strains will be presented....

    17. STRAINED OFF BREAST MILK: PRO AND CONTRA

      Directory of Open Access Journals (Sweden)

      O.L. Lukoyanova

      2010-01-01

      Full Text Available The questions of feeding of children with strained off breast milk are discussed in this article. Author presents medical indications to such type of feeding, peculiarities and rules of storage of strained off milk. There is a brief literature review on the influence of different factors on the composition of strained off breast milk.Key words: strained milk, breast feeding, pasteurization, freezing.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(2:70-73

    18. Haemophilus ducreyi Cutaneous Ulcer Strains Are Nearly Identical to Class I Genital Ulcer Strains.

      Directory of Open Access Journals (Sweden)

      Dharanesh Gangaiah

      Full Text Available Although cutaneous ulcers (CU in the tropics is frequently attributed to Treponema pallidum subspecies pertenue, the causative agent of yaws, Haemophilus ducreyi has emerged as a major cause of CU in yaws-endemic regions of the South Pacific islands and Africa. H. ducreyi is generally susceptible to macrolides, but CU strains persist after mass drug administration of azithromycin for yaws or trachoma. H. ducreyi also causes genital ulcers (GU and was thought to be exclusively transmitted by microabrasions that occur during sex. In human volunteers, the GU strain 35000HP does not infect intact skin; wounds are required to initiate infection. These data led to several questions: Are CU strains a new variant of H. ducreyi or did they evolve from GU strains? Do CU strains contain additional genes that could allow them to infect intact skin? Are CU strains susceptible to azithromycin?To address these questions, we performed whole-genome sequencing and antibiotic susceptibility testing of 5 CU strains obtained from Samoa and Vanuatu and 9 archived class I and class II GU strains. Except for single nucleotide polymorphisms, the CU strains were genetically almost identical to the class I strain 35000HP and had no additional genetic content. Phylogenetic analysis showed that class I and class II strains formed two separate clusters and CU strains evolved from class I strains. Class I strains diverged from class II strains ~1.95 million years ago (mya and CU strains diverged from the class I strain 35000HP ~0.18 mya. CU and GU strains evolved under similar selection pressures. Like 35000HP, the CU strains were highly susceptible to antibiotics, including azithromycin.These data suggest that CU strains are derivatives of class I strains that were not recognized until recently. These findings require confirmation by analysis of CU strains from other regions.

    19. Strain gradient effects in surface roughening

      DEFF Research Database (Denmark)

      Borg, Ulrik; Fleck, N.A.

      2007-01-01

      evidence for strain gradient effects. Numerical analyses of a bicrystal undergoing in-plane tensile deformation are also studied using a strain gradient crystal plasticity theory and also by using a strain gradient plasticity theory for an isotropic solid. Both theories include an internal material length...

    20. Engineering piezoresistivity using biaxially strained silicon

      DEFF Research Database (Denmark)

      Pedersen, Jesper Goor; Richter, Jacob; Brandbyge, Mads

      2008-01-01

      of the piezocoefficient on temperature and dopant density is altered qualitatively for strained silicon. In particular, we find that a vanishing temperature coefficient may result for silicon with grown-in biaxial tensile strain. These results suggest that strained silicon may be used to engineer the iezoresistivity...

    1. drug resistant strains of Salmonella enterica

      African Journals Online (AJOL)

      Conclusions: The aqueous extract of Thonningia sanguinea can provide an alternative therapy for the treatment of salmonellosis, mainly for typhoid fever caused by MDR strains of S. Typhi.The extract also inhibits S.Hadar a MDR emerging strain in Ivory Coast. Keywords: Thonningia sanguinea; Salmonella, MDR strains, ...

    2. Development of high temperature strain gage, (5)

      International Nuclear Information System (INIS)

      Yuuki, Hiroshi; Kobayashi, Yukio; Kanai, Kenji; Yamaura, Yoshio

      1976-01-01

      Development and improvement of resistance wire type strain gages usable for experimental measurement of thermal strains generated at high temperature in various structures and equipments that consist of a Fast Breeder Reactor have been carried out, and various characteristics of the strain gages have been investigated. Based on the results obtained up to now, development and research of this time mainly aim to improve strain and fatigue characteristics. As the results, characteristics of strain gages with sensing elements of nichrome V are improved, specifically mechanical hysteresis is decreased, strain limit is increased, etc. Also, improvement is recognized in thermal output, and it becomes clear that dummy gages work effectively. However, a filling method of MgO and an inserting method of active-dummy elements are selected as primary objects to improve strain characteristics, and many hours are taken for these objects, so confirmations of characteristics of platinum-tungsten strain gages, strain sensing elements of which are troublesome to produce, have not been completely done, though the performance of the gages has been improved in several points. As to nichrome V strain gages, there is a fair prospect of obtaining ones, specifications of which are quite close to the goal, though problems in manufacturing technics remain for future. As to platinum-tungsten strain gages, it is expected that similar strain gages to nichrome V are obtainable by improvement in manufacturing of sensing elements. (auth.)

    3. Strain path dependency in metal plasticity

      NARCIS (Netherlands)

      Viatkina, E.M.; Brekelmans, W.A.M.; Geers, M.G.D.

      2003-01-01

      A change in strain path has a significant effect on the mechanical response of metals. Strain path change effects physically originate from a complex microstructure evolution. This paper deals with the contribution of cell structure evolution to the strain path change effect. The material with cells

    4. Stress and strain measurements in solids

      International Nuclear Information System (INIS)

      Askegaard, V.

      1978-01-01

      A design basis is given for stress- and strain cells to be used in a solid either externally loaded or with a stressfree strain field (for example shrinkage). A stress- and a strain cell has been designed for use in granular materials. Calibration tests show either good or reasonably good correspondance with calculated values. (orig.) [de

    5. Spontaneous abortion and physical strain around implantation

      DEFF Research Database (Denmark)

      Hjollund, N H; Jensen, Tina Kold; Bonde, Jens Peter

      2000-01-01

      pregnancy the women recorded physical strain prospectively in a structured diary. Physical strain around the time of implantation was associated with later spontaneous abortion. The adjusted risk ratio for women who reported physical strain higher than average at day 6 to 9 after the estimated date...

    6. Strain engineering of van der Waals heterostructures

      NARCIS (Netherlands)

      Vermeulen, Paul A.; Mulder, Jefta; Momand, Jamo; Kooi, Bart J.

      2018-01-01

      Modifying the strain state of solids allows control over a plethora of functional properties. The weak interlayer bonding in van der Waals (vdWaals) materials such as graphene, hBN, MoS2, and Bi2Te3 might seem to exclude strain engineering, since strain would immediately relax at the vdWaals

    7. On lower order strain gradient plasticity theories

      DEFF Research Database (Denmark)

      Niordson, Christian Frithiof; Hutchinson, J. W.

      2003-01-01

      By way of numerical examples, this paper explores the nature of solutions to a class of strain gradient plasticity theories that employ conventional stresses, equilibrium equations and boundary conditions. Strain gradients come into play in these modified conventional theories only to alter...... the tangent moduli governing increments of stress and strain. It is shown that the modification is far from benign from a mathematical standpoint, changing the qualitative character of solutions and leading to a new type of localization that is at odds with what is expected from a strain gradient theory....... The findings raise questions about the physical acceptability of this class of strain gradient theories....

    8. Spontaneous abortion and physical strain around implantation

      DEFF Research Database (Denmark)

      Hjøllund, Niels Henrik Ingvar; Jensen, T.K.; Bonde, J.P.

      2000-01-01

      Existing studies of physical strain and spontaneous abortion are mainly retrospective or based only on pregnancies that have survived the first trimester. Furthermore, almost all studies have relied on averaged measures of physical strain, which tend to blur an effect if peak values during short...... pregnancy the women recorded physical strain prospectively in a structured diary. Physical strain around the time of implantation was associated with later spontaneous abortion. The adjusted risk ratio for women who reported physical strain higher than average at day 6 to 9 after the estimated date...

    9. Local strains in waste tank deflagration analysis

      International Nuclear Information System (INIS)

      Bryan, B.J.; Flanders, H.E. Jr.

      1993-01-01

      In recent years extensive effort has been expended to qualify buried nuclear waste storage tanks under accident conditions. One of these conditions is deflagration of the combustible gases which may build up over time. While much work has been done to calculate the general strain state, less effort has been made to address the local strains at structural discontinuities. An analytical method is presented for calculating these local strains and combining them with the general strain state. A closed form solution of the local strains is compared to a finite element solution

    10. Sensibility of different wheat varieties (strains) to Ar+ implantation

      International Nuclear Information System (INIS)

      Cui Huanhu; Jing Hua; Ma Aiping; Kang Xiuli; Yang Liping; Huang Mingjing; Ma Buzhou; Shanxi Academy of Agricultural Sciences, Taiyuan

      2005-01-01

      The sensibility of different wheat varieties (strains) to Ar + implantation was studied. The results showed that the survival rate of 21 wheat varieties (strains) at the dose of 6 x 10 16 Ar + /cm 2 could be divided into five groups: surplus sensitive varieties (strains), sensitive varieties (strains), transitional varieties (strains), obtuse varieties (strains) and surplus obtuse varieties (strains). The sensibility of wheat varieties (strains) to Ar + injection is high-moisture-fertility wheat varieties (strains) > medium-moisture-fertility wheat varieties (strains) > dry land wheat varieties (strains). The study has provided theoretical basis in induced mutation medial lethal dose of different wheat varieties (strains) to Ar + implantation. (authors)

    11. Stress-strain properties of railway steel at strain rates of upto 105 per second

      International Nuclear Information System (INIS)

      Hashmi, M.S.J.; Islam, M.N.

      1985-01-01

      This paper presents the stress-strain characteristics of railway steel at strain rates of up to 10 5 /s at room temperature determined by a new technique. In determining the results, account has been taken of the strain-rate variation, the total strain and the strain rate history. The effect of friction, material inertia and temperature rise is also assessed and an empirical constitutive equation describing the strain-rate and strain sensitive flow stress for this type of steel is proposed. (orig.)

    12. Strain quantification in epitaxial thin films

      International Nuclear Information System (INIS)

      Cushley, M

      2008-01-01

      Strain arising in epitaxial thin films can be beneficial in some cases but devastating in others. By altering the lattice parameters, strain may give a thin film properties hitherto unseen in the bulk material. On the other hand, heavily strained systems are prone to develop lattice defects in order to relieve the strain, which can cause device failure or, at least, a decrease in functionality. Using convergent beam electron diffraction (CBED) and high-resolution transmission electron microscopy (HRTEM), it is possible to determine local strains within a material. By comparing the results from CBED and HRTEM experiments, it is possible to gain a complete view of a material, including the strain and any lattice defects present. As well as looking at how the two experimental techniques differ from each other, I will also look at how results from different image analysis algorithms compare. Strain in Si/SiGe samples and BST/SRO/MgO capacitor structures will be discussed.

    13. Assessment of Effectiveness of Cool Coat in Reducing Heat Strain among Workers in Steel Industry.

      Science.gov (United States)

      Parameswarappa, S B; Narayana, J

      2017-01-01

      A research study was conducted to assess the effectiveness of cool coat in reducing heat strain among workers exposed to heat in a steel plant located in south India. The study consists of assessing heat strain of workers exposed to heat in a steel plant by measuring physiological reactions of workers such as pulse rate and core body temperature with and without cool coat. The coal coat taken for this study was procured from M/s Yamuna Industries, Noida. Out of 140 employees exposed to heat hazard, 101 employees were examined in this study. Study was done in important production units in steel plant having heat hazard. Workers were interviewed and examined and information regarding thermal comfort was collected. First, the heat strain was assessed when the workers were not using cool coats. The air temperature was measured at all hot zone workplaces and found in the range of 34 0 C to 39.4 0 C (Mean: 36.54 0 C & S.D: 1.54). Physiological response such as core body temperature, pulse rate and blood pressure of workers exposed to heat hazard were measured before & after work to know the heat strain sustained by workers when they were working. Maximum core body temperature after work was found to be 39.3 0 C (Mean; 38.52 & S.D; 0.7). Maximum pulse rate of workers after work was found to be 120 beats/minute (Mean; 94.96 beats/minute, S.D: 13.11). The study indicate core body temperature of workers was found more than the permissible exposure limit prescribed by ACGIH, indicating the heat strain sustained by workers is significant, whereas the pulse rate and blood pressure was found normal & not exceeded the limits. Second, with cool coat, the heat strain was assessed among 10 workers selected from the 101 employees. Core body temperature was measured before and soon after work, The core body temperature recorded soon after work was in the range of 35.5 - 37.20C (Mean 36.36, SD= 0.52), indicating a drop in the core body temperature. In this study, a core body

    14. SNF project's MCO compliance assessment with DOE ''general design criteria,'' order 6430.1A and ''SNF project MCO additional NRC requirements,'' HNF-SD-SNF-DB-005

      International Nuclear Information System (INIS)

      GOLDMANN, L.H.

      1999-01-01

      This document is presented to demonstrate the MCOs compliance to the major design criteria invoked on the MCO. This document is broken down into a section for the MCO's evaluation against DOE Order 6430.1A General Design Criteria sixteen divisions and then the evaluation of the MCO against HNF-SD-SNF-DB-005 ''Spent Nuclear Fuel Project Multi-Canister Overpack Additional NRC Requirements.'' The compliance assessment is presented as a matrix in tabular form. The MCO is the primary container for the K-basin's spent nuclear fuel as it leaves the basin pools and through to the 40 year interim storage at the Canister Storage Building (CSB). The MCO and its components interface with; the K basins, shipping cask and transportation system, Cold Vacuum Drying facility individual process bays and equipment, and CSB facility including the MCO handling machine (MHM), the storage tubes, and the MCO work stations where sampling, welding, and inspection of the MCO is performed. As the MCO is the primary boundary for handling, process, and storage, its main goals are to minimize the spread of its radiological contents to the outside of the MCO and provide for nuclear criticality control. The MCO contains personnel radiation shielding only on its upper end, in the form of a shield plug, where the process interfaces are located. Shielding beyond the shield plug is the responsibility of the using facilities. The design of the MCO and its components is depicted in drawings H-2-828040 through H-2-828075. Not every drawing number in the sequence is used. The first drawing number, H-2-828040, is the drawing index for the MCO. The design performance specification for the MCO is HW-S-0426, and was reviewed and approved by the interfacing design authorities, the safety, regulatory, and operations groups, and the local DOE office. The current revision for the design performance specification is revision 5. The designs of the MCO have been reviewed and approved in a similar way and the reports

    15. Di-(2-ethylhexyl) phthalate could disrupt the insulin signaling pathway in liver of SD rats and L02 cells via PPARγ

      Energy Technology Data Exchange (ETDEWEB)

      Zhang, Wang; Shen, Xin-Yue; Zhang, Wen-wen; Chen, Hao [Institute of Clinical Pharmacology of Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine of Education Ministry, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, 230032, Anhui (China); Xu, Wei-ping, E-mail: xu_weiping666@163.com [Affiliated Anhui Provincial Hospital, Anhui Medical University, Hefei 230001, Anhui (China); Wei, Wei, E-mail: wwei@ahmu.edu.cn [Institute of Clinical Pharmacology of Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine of Education Ministry, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, 230032, Anhui (China)

      2017-02-01

      Di-(2-ethylhexyl)-phthalate (DEHP), a ubiquitous industrial pollutant in our daily life, has been reported to cause adverse effects on glucose homeostasis and insulin sensitivity in epidemiological studies previously. Recently, it has been reported to be an endocrine disrupter and ligand to peroxisome proliferator activated receptor, which could influence the homeostasis of liver metabolic systems and contribute to the development of type-2 diabetes. However, the potential mechanisms are not known yet. This study was designed to solve these problems with male SD rats and normal human hepatocyte line, L02 cells, exposed to DEHP for toxicological experiments. Adult male SD rats were divided into four groups, normal group fed with regular diets and three DEHP-treated groups (dissolved in olive oil at doses of 0.05, 5 and 500 mg/kg body weight, respectively, once daily through gastric intubations for 15 weeks). L02 cells were divided into 6 groups, normal group with 5, 10, 25, 50, and 100 μmol/l DEHP groups. DEHP-exposed rats exhibited significant liver damage, glucose tolerance, and insulin tolerance along with reduced expression of insulin receptor and GLUT4 proteins in the liver tissues. The results of in vitro experiments could determine that the DEHP-induced activation of peroxisome proliferator activated receptor γ (PPARγ) played a key role in the production of oxidative stress and down-regulated expression of insulin receptor and GLUT4 proteins in L02 cells. This conclusion could be supported by the results of in vitro experiments, in which the cells were exposed to DEHP with GW9662 (PPARγ inhibitor). In general, these results highlight the key role of PPARγ in the process of insulin resistance induced by DEHP. - Highlights: • DEHP exacerbates insulin resistance both in liver tissues and cells. • Expression of insulin receptor and GLUT4 were altered with PPARγ. • DEHP can induce oxidative stress to disrupt the metabolic homeostasis. • The dose of

    16. Di-(2-ethylhexyl) phthalate could disrupt the insulin signaling pathway in liver of SD rats and L02 cells via PPARγ

      International Nuclear Information System (INIS)

      Zhang, Wang; Shen, Xin-Yue; Zhang, Wen-wen; Chen, Hao; Xu, Wei-ping; Wei, Wei

      2017-01-01

      Di-(2-ethylhexyl)-phthalate (DEHP), a ubiquitous industrial pollutant in our daily life, has been reported to cause adverse effects on glucose homeostasis and insulin sensitivity in epidemiological studies previously. Recently, it has been reported to be an endocrine disrupter and ligand to peroxisome proliferator activated receptor, which could influence the homeostasis of liver metabolic systems and contribute to the development of type-2 diabetes. However, the potential mechanisms are not known yet. This study was designed to solve these problems with male SD rats and normal human hepatocyte line, L02 cells, exposed to DEHP for toxicological experiments. Adult male SD rats were divided into four groups, normal group fed with regular diets and three DEHP-treated groups (dissolved in olive oil at doses of 0.05, 5 and 500 mg/kg body weight, respectively, once daily through gastric intubations for 15 weeks). L02 cells were divided into 6 groups, normal group with 5, 10, 25, 50, and 100 μmol/l DEHP groups. DEHP-exposed rats exhibited significant liver damage, glucose tolerance, and insulin tolerance along with reduced expression of insulin receptor and GLUT4 proteins in the liver tissues. The results of in vitro experiments could determine that the DEHP-induced activation of peroxisome proliferator activated receptor γ (PPARγ) played a key role in the production of oxidative stress and down-regulated expression of insulin receptor and GLUT4 proteins in L02 cells. This conclusion could be supported by the results of in vitro experiments, in which the cells were exposed to DEHP with GW9662 (PPARγ inhibitor). In general, these results highlight the key role of PPARγ in the process of insulin resistance induced by DEHP. - Highlights: • DEHP exacerbates insulin resistance both in liver tissues and cells. • Expression of insulin receptor and GLUT4 were altered with PPARγ. • DEHP can induce oxidative stress to disrupt the metabolic homeostasis. • The dose of

    17. KONSTRUKSI SOSIAL GURU TERHADAP PEMBELAJARAN IPS DI SD INPRES 6/86 LABURASSENG DESA LABURASSENG KECAMATAN LIBURENG KABUPATEN BONE SULAWESI SELATAN

      Directory of Open Access Journals (Sweden)

      Muhammad Taufiq Halim

      2015-06-01

      Full Text Available Penelitian ini dilatarbelakangi oleh jauhnya lokasi sekolah dari pusat perkotaan sehingga menyebabkan kurangnya informasi yang masuk ke sekolah ini. Tujuan penelitian ini adalah mendeskripsikan konstruksi sosial guru terhadap pembelajaran IPS, mendeskripsikan implementasi pembelajaran IPS di SD Inpres 6/86 Laburasseng, mendeskripsikan dampak pembelajaran IPS di SD Inpres 6/86 Laburasseng. Penelitian ini termasuk penelitian kualitatif. Teknik pengumpulan data dilakukan dengan wawancara mendalam, observasi dan dokumentasi. Teknik analisis dalam penelitian ini dengan menggunakan model interaktif yakni pengumpulan data, reduksi data, penyajian data, dan verifikasi data. Hasil penelitian ini ditemukan bahwa konstruksi sosial guru terhadap pembelajaran IPS berbeda-beda khususnya pada tahap objektifikasi dan terjadi pergeseran pandangan terhadap pembelajaran IPS yang ideal yang menyebabkan implementasi dari pembelajaran IPS menyimpang sehingga berdampak pada perilaku siswa. Berdasarkan hal tersebut disarankan agar guru-guru lebih aktif untuk mengikuti pelatihan-pelatihan serta diklat-diklat dan mencari informasi yang lebih banyak untuk menambah wawasan tentang pembelajaran IPS. The research was distributed by school location away from urban centres so that the cause of the lack of information coming into this school. The purpose of this study is to describe the social construction of teachers towards social science learning, social science learning implementation described in the primary presidential instruction 6/86 Laburasseng, described the impact of  social science learning in the primary presidential instruction 6/86 Laburasseng. This research includes qualitative research. The technique of data collection conducted in-depth interviews with, observation and documentation. Analytical techniques in the study with the use of interactive models i.e., data collection, data reduction, data presentation, and data verification. The research found that

    18. Studies on Drosophila radiosensitivity strains

      International Nuclear Information System (INIS)

      Varentsova, E.R.; Sharygin, V.I.; Khromykh, Yu.U.

      1985-01-01

      Fertility of radiosensitive mutant drosophila female strain rad (2) 201 61 after irradiation and frequency of dominant lethal mutations (DLM), induced by γ-radiation for 0-5 h and 5-7 days, are investigated. It is shown, that oocytes of the mutant strain are more radiosensitive as compared with cells of mongrel flies as to criterion of DLM appearance over the period of maturing. Early oocytes of stages 2-7 are the most sensitive, i.e. at the stages, corresponding to the manifestation of previously established recombination-defective properties of mutations rad (2) 201 61 . It is also sown, that doses of γ-rays, exceeding 10 Gy produce a strong sterilizing effect on mutant females due to destruction and resorption of egg chambers, irradiated at the stages of previtellogenetic growth of oocytes. In females, carrying mutation of radiosensitivity there is no direct correlation betwen sensitivity of oocytes proper to DLM induction and sensitivity of egg folleicles to resorbing effect of γ-rays. The ways of possible involvement of mutant locus studied into genetic processes in various specialized cells of drosophila

    19. Strain differences in the response to morphine on incorporation of 3H-lysine into rat brain protein

      International Nuclear Information System (INIS)

      Ford, D.H.; Rhines, R.K.; Levi, M.A.

      1977-01-01

      The effect of morphine on the specific activity (SA) of lysine in the plasma free amino acid (FFA) fraction and in the cerebral cortical FAA and protein fractions, as well as on the specific accumulation and incorporation, was determined in male Sprague-Dawley and Wistar rats at various time intervals after intravenous injection of drug and amino acid into unanesthetized animals. The lysine SA was higher in Sprague-Dawley than in Wistar rats in the plasma and brain FAA fraction and in the protein fraction. In the SD strain, morphine decreased the SA of plasma FAA significantly, but had only slight effects in the Wistar strain. In the cortical gray matter, morphine elevated the SA of lysine significantly in both strains. SA of the lysine in cerebral cortical protein increased in both strains with time. When the data for the free amino acids were expressed in terms of specific accumulation, the observed rates were higher in the Sprague-Dawley animals and reached a point of maximal concentration, which was not observed in animals of the Wistar strain. Morphine elevated the levels of specific accumulation of lysine into the cortical free amino acid pool in both strains of rat. It is concluded that Sprague-Dawley and Wistar rats are not equivalent in relation to the accumulation of an amino acid in the brain FAA pool from the plasma and that the effect of morphine on specific incorporation of lysine into brain protein is greater in Wistar rats. (author)

    20. Non-LTE analysis of extremely helium-rich stars. The hot sdO stars LSE 153, 259 and 263

      Science.gov (United States)

      Husfeld, D.; Butler, K.; Heber, U.; Drilling, J. S.

      1989-01-01

      Results of a non-LTE fine analysis based mainly on high-resolution CASPEC spectra for three extremely helium-rich sdO stars are discussed in order to explain hydrogen deficiency in single stars. High temperature (Teff = 70,000 to 75,000 K) and a position in the log Teff - log g diagram were found close to the Eddington limit. Various abundance estimates are derived for hydrogen (upper limits only), carbon, nitrogen, and magnesium. Hydrogen is reduced to less than 10 percent by number in LSE 153 and LSE 263, and to less than 5 percent in LSE 259. The hydrogen deficiency is accompanied by nitrogen- and carbon-enrichment in LSE 153 and LSE 259 only. In LSE 263, carbon is depleted by about 1 dex. Stellar masses obtained by assuming that a core mass-luminosity relation holds for these stars, were found to be in the range 0.6-0.9 solar mass, yielding luminosities log L/L:solar = 3.7-4.5. Two of the program stars (LSE 153 and 259) appear to be possible successors of the R CrB and helium B stars, whereas the third star (LSE 263) displays a much lower carbon content in its photosphere making it an exceptional case among the known hydrogen deficient stars.

    1. PENINGKATAN HASIL BELAJAR IPA MELALUI PENERAPAN MODEL KOOPERATIF TIPE STUDENT TEAM ACHIEVEMENT DIVISION (STAD PADA SISWA KELAS IV SD NO. 2 BENG GIANYAR TAHUN PELAJARAN 2015/2016

      Directory of Open Access Journals (Sweden)

      Desak Putu Rohika

      2017-10-01

      Full Text Available This study aims to determine the yield increase fourth grade students learn science even in SD No. 6 Bunutan after the implementation of cooperative learning model Student Team Achievement Division (STAD. This is the kind of research is classroom action research was conducted in two cycles. Each cycle consists of planning, action, observation, and reflection. The study involved a fourth grade student No.. 6 Bunutan which totaled 26 people. Data collection methods used for science learning outcomes is a test method. Data were analyzed using descriptive quantitative method. The results showed that, the implementation of STAD models can improve science learning outcomes. In the first cycle, the average value of 68.27 students belonging to the category of being and mastery learning of 73.08%. In the second cycle the average value of 82.5 students belonging to either category and mastery learning by 100%. Average student learning outcomes from the first cycle to the second cycle increased by 14.23%, and mastery learning from cycle I to cycle II of 26.92%.

    2. Analysis of aquifer tests conducted in boreholes USW WT-10, UE-25 WT No. 12, and USW SD-7, 1995-96, Yucca Mountain, Nevada

      International Nuclear Information System (INIS)

      O'Brien, G.M.

      1997-01-01

      Single-borehole aquifer tests were conducted in three boreholes in the Yucca Mountain area between March 1995 and January 1996 to obtain estimates of borehole specific capacity and aquifer transmissivity. Analysis of aquifer testing in borehole USW SD-7 also resulted in an estimate of reservoir volume. Aquifer-test data were analyzed with the Cooper and Jacob straight-line method, two modified Theis nonequilibrium equation solutions, and a modified reservoir-limit solution. The highest estimates of transmissivity were in borehole USW WT-10, completed in the Topopah Spring Tuff. Mean transmissivity, based on the results of three drawdown tests, was 1,600 meters squared per day. Mean specific capacity in borehole USW WT-10 after 5 hours of pumping was 1,100 meters squared per day, and was estimated to be 740 meters squared per day after 24 hours of pumping. Aquifer testing in borehole UE-25 WT No. 12 appeared to be significantly affected by well losses. A mean transmissivity of 7 meters squared per day was obtained on the basis of analysis of three drawdown tests in borehole UE-25 WT No. 12. Mean specific capacity in borehole UE-25 WT No. 12, after 24 hours of pumping, was 7 meters squared per day. Borehole UE-25 WT No. 12 seemed to be producing water from fractures that could provide only a limited amount of water to the borehole

    3. SD simulation study on degraded farmland policy on farming-pastoral area under the constrains of water resources-Taking Tongliao City of Inner Mongolia as example

      Science.gov (United States)

      Xu, D. P.; Zhao, B.; Li, T. S.; Zhu, J. W.; Yu, M. M.

      2017-08-01

      Water resources are the primary factor in restricting the sustainable development of farming-pastoral regions. To support the sustainable development of water resources, whether or not the land uses patterns of farming-pastoral areas is a reasonably important issue. This paper takes Tongliao city as example for the purpose of sustainably developing the farming-pastoral area in the north. Several scientific preductions and evaluations were conducted to study the farming-pastoral landuse pattern, which is the key problem that effects sustainable development of farming-pastoral areas. The paper then proposes that 1:7 landuse pattern is suitable for the sustainable development of farming-pastotal area. Based on the analysis of the research findings on sustainable development of farming-pastoral area, the paper established a suitability evaluation indicators system of degraded farmland policies in Tongliao city, and used an Analytical Hierarchy Process (AHP) method to determine the weight to run system dynamic (SD) model. The simulation results were then obtained on social economic ecological development in Tongliao city under different degraded farmland policies, and used the comprehensive evaluation model to optimize the results. It is concluded that stabilizing the policy of degraded farmland policy is the preferential policy in Tongliao, which provides useful theoretical research for the sustainable development of farming-pastoral area.

    4. Time Course of the Changes in Novel Trioxane Antimalarial 99/411 Pharmacokinetics upon Antiepileptic Drugs Co-Administration in SD Rats

      Directory of Open Access Journals (Sweden)

      Yeshwant Singh

      2014-01-01

      Full Text Available Objective. The study aimed to evaluate the influences of coadministration of antiepileptic drugs (AEDs on an antimalarial candidate 99/411 pharmacokinetic (PK profile. Method. For this, single oral dose PK drug interaction studies were conducted between 99/411 and FDA approved AEDs, namely, Phenytoin (PHT, Carbamazepine (CBZ, and Gabapentin (GB in both male and female SD rats, to assess the coadministered and intersexual influences on 99/411 PK profile. Results. Studies revealed that there were no significant alterations in the PK profile of 99/411 upon PHT and CBZ coadministration in both male and female rats, while systemic exposure of 99/411 was significantly increased by about 80% in female rats upon GB coadministration. In terms of AUC, there was an increase from 2471 ± 586 to 4560 ± 1396 ng·h/mL. Overall, it was concluded that simultaneous administration of AEDs with 99/411 excludes the requirements for dose adjustment, additional therapeutic monitoring, contraindication to concomitant use, and/or other measures to mitigate risk, except for GB coadministration in females. These findings are further helpful to predict such interactions in humans, when potentially applied through proper allometric scaling to extrapolate the data.

    5. Noninvasive characterization of carotid plaque strain.

      Science.gov (United States)

      Khan, Amir A; Sikdar, Siddhartha; Hatsukami, Thomas; Cebral, Juan; Jones, Michael; Huston, John; Howard, George; Lal, Brajesh K

      2017-06-01

      Current risk stratification of internal carotid artery plaques based on diameter-reducing percentage stenosis may be unreliable because ischemic stroke results from plaque disruption with atheroembolization. Biomechanical forces acting on the plaque may render it vulnerable to rupture. The feasibility of ultrasound-based quantification of plaque displacement and strain induced by hemodynamic forces and their relationship to high-risk plaques have not been determined. We studied the feasibility and reliability of carotid plaque strain measurement from clinical B-mode ultrasound images and the relationship of strain to high-risk plaque morphology. We analyzed carotid ultrasound B-mode cine loops obtained in patients with asymptomatic ≥50% stenosis during routine clinical scanning. Optical flow methods were used to quantify plaque motion and shear strain during the cardiac cycle. The magnitude (maximum absolute shear strain rate [MASSR]) and variability (entropy of shear strain rate [ESSR] and variance of shear strain rate [VSSR]) of strain were combined into a composite shear strain index (SSI), which was assessed for interscan repeatability and correlated with plaque echolucency. Nineteen patients (mean age, 70 years) constituting 36 plaques underwent imaging; 37% of patients (n = 7) showed high strain (SSI ≥0.5; MASSR, 2.2; ESSR, 39.7; VSSR, 0.03) in their plaques; the remaining clustered into a low-strain group (SSI routine B-mode imaging using clinical ultrasound machines. High plaque strain correlates with known high-risk echolucent morphology. Strain measurement can complement identification of patients at high risk for plaque disruption and stroke. Copyright © 2017 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

    6. IMI - An information system for effective Multidisciplinary Incident Management

      NARCIS (Netherlands)

      Lee, M.D.E. van der; Vugt, M. van der

      2004-01-01

      The field of crisis response and disaster management can be characterized, upon many other factors, by distributed operations, not daily routine work and multidisciplinary aspects. In designing and developing information systems for crisis response these factors need special attention. On behalf of

    7. Purification and characterization of nitrilase from Fusarium solani IMI196840

      Czech Academy of Sciences Publication Activity Database

      Vejvoda, Vojtěch; Kubáč, David; Davidová, A.; Kaplan, Ondřej; Šulc, Miroslav; Šveda, Ondřej; Chaloupková, R.; Martínková, Ludmila

      2010-01-01

      Roč. 45, č. 7 (2010), s. 1115-1120 ISSN 1359-5113 R&D Projects: GA AV ČR IAA500200708; GA MŠk(CZ) LC06010; GA MŠk OC09046; GA ČR GD305/09/H008; GA MPO FT-TA5/043 Institutional research plan: CEZ:AV0Z50200510 Keywords : fusarium solani * nitrilase * purification Subject RIV: EE - Microbiology, Virology Impact factor: 2.648, year: 2010

    8. IMIS: Integrated Marine Installation System for offshore turbines

      Energy Technology Data Exchange (ETDEWEB)

      NONE

      2003-07-01

      The report describes a feasibility study on the Integrated Marine Installation System for offshore wind turbines. The aspects covered are (1) Background and why the study is required; (2) Aims and objectives of the project; (3) Summary of methods adopted; (4) Design criteria according to the area for deployment; (5) Conclusions and recommendations. The ultimate goal will be to install and secure the wind turbine in position using an integrated approach to avoid using lifting vessels. To date, an initial feasibility study has been carried out where four different concepts were considered. The next phase of the project will be to address a number of possible risks and constraints before the chosen concept can be demonstrated to be viable. The work is being carried out by Setech Ltd, Armstrong Technology Associates Ltd and Smith Rea Energy Ltd for the DTI.

    9. Nierozstrzygalność - drugie imię dekonstrukcji?

      Directory of Open Access Journals (Sweden)

      Elżbieta Winiecka

      2007-04-01

      Full Text Available The article focuses on the problem of undecidability - the main feature of literature according to Derrida. Numerous examples of undecidability shows that it is not deconstruction which has found this kind of reading. For structuralists undecidability was a feature of poetry. Derrida broadens this onto all literary texts. Cancelling oposition between 'inside' and 'outside' he liquidates all natural for work contests: historical, sociological etc., and reduces literary text to the endless re-interpretation. It makes literary sigificants insignificant for culture and human being. Exploration of the margins of the literary texts thwarts hierarchy of importancy and opens the door for different kinds of abuses. This is why the author argues with Derrida's thesis and guards traditional role of the autor, reader and literature.

    10. The IMI PROTECT project: purpose, organizational structure, and procedures.

      Science.gov (United States)

      Reynolds, Robert F; Kurz, Xavier; de Groot, Mark C H; Schlienger, Raymond G; Grimaldi-Bensouda, Lamiae; Tcherny-Lessenot, Stephanie; Klungel, Olaf H

      2016-03-01

      The Pharmacoepidemiological Research on Outcomes of Therapeutics by a European ConsorTium (PROTECT) initiative was a collaborative European project that sought to address limitations of current methods in the field of pharmacoepidemiology and pharmacovigilance. Initiated in 2009 and ending in 2015, PROTECT was part of the Innovative Medicines Initiative, a joint undertaking by the European Union and pharmaceutical industry. Thirty-five partners including academics, regulators, small and medium enterprises, and European Federation of Pharmaceuticals Industries and Associations companies contributed to PROTECT. Two work packages within PROTECT implemented research examining the extent to which differences in the study design, methodology, and choice of data source can contribute to producing discrepant results from observational studies on drug safety. To evaluate the effect of these differences, the project applied different designs and analytic methodology for six drug-adverse event pairs across several electronic healthcare databases and registries. This papers introduces the organizational structure and procedures of PROTECT, including how drug-adverse event and data sources were selected, study design and analyses documents were developed, and results managed centrally. Copyright © 2016 John Wiley & Sons, Ltd.

    11. The IMI PROTECT project : purpose, organizational structure, and procedures

      NARCIS (Netherlands)

      Reynolds, Robert F; Kurz, Xavier; de Groot, Mark C H|info:eu-repo/dai/nl/313936455; Schlienger, Raymond G; Grimaldi-Bensouda, Lamiae; Tcherny-Lessenot, Stephanie; Klungel, Olaf H|info:eu-repo/dai/nl/181447649

      2016-01-01

      The Pharmacoepidemiological Research on Outcomes of Therapeutics by a European ConsorTium (PROTECT) initiative was a collaborative European project that sought to address limitations of current methods in the field of pharmacoepidemiology and pharmacovigilance. Initiated in 2009 and ending in 2015,

    12. Computational Strain Gradient Crystal Plasticity

      DEFF Research Database (Denmark)

      Niordson, Christian Frithiof; Kysar, Jeffrey W.

      2011-01-01

      A model for strain gradient crystal visco-plasticity is formulated along the lines proposed by Fleck andWillis (2009) for isotropic plasticity. Size-effects are included in the model due to the addition of gradient terms in both the free energy as well as through a dissipation potential. A finite...... element solution method is presented, which delivers the slip-rate field and the velocity-field based on two minimum principles. Some plane deformation problems relevant for certain specific orientations of a face centered cubic crystal under plane loading conditions are studied, and effective in......-plane parameters are developed based on the crystallographic properties of the material. The problem of cyclic shear of a single crystal between rigid platens is studied as well as void growth of a cylindrical void....

    13. Thermoresistance in radioresistant strains of 'Drosophila nebulosa'

      International Nuclear Information System (INIS)

      Kratz, F.L.

      1977-01-01

      The detection of thermoresistance in radioresistant strains of 'D. nebulosa' is described, as well as some conclusions on the genetic nature of these differences are presented. The strains used in this experiment were MF 204, from 'Morro de Ferro', in Pocos de Caldas (MG) (one of the biggest radioactive anomalies in the world) whose radioresistance is due to its additive genetic components (Kratz, 1973 and 1975); 85(87) R, an induced radioresistant strain; and MF K a control 'pooled' strain obtained near 'Morro do Ferro'. Survival tests, 72 hours after temperature shocks, performed in the interval of 36 0 C to 39 0 C showed a decreasing gradient of thermoresistance with the following regression coefficients: MF 204 b= - 5,4; 85(87)R b= - 7,2 and MF K b= - 7,9. Bifactorial analysis (strains and sexes) performed at 38 0 C and 39 0 C confirmed differences among strains (P [pt

    14. The many shades of prion strain adaptation.

      Science.gov (United States)

      Baskakov, Ilia V

      2014-01-01

      In several recent studies transmissible prion disease was induced in animals by inoculation with recombinant prion protein amyloid fibrils produced in vitro. Serial transmission of amyloid fibrils gave rise to a new class of prion strains of synthetic origin. Gradual transformation of disease phenotypes and PrP(Sc) properties was observed during serial transmission of synthetic prions, a process that resembled the phenomenon of prion strain adaptation. The current article discusses the remarkable parallels between phenomena of prion strain adaptation that accompanies cross-species transmission and the evolution of synthetic prions occurring within the same host. Two alternative mechanisms underlying prion strain adaptation and synthetic strain evolution are discussed. The current article highlights the complexity of the prion transmission barrier and strain adaptation and proposes that the phenomenon of prion adaptation is more common than previously thought.

    15. Effect of strain rate and temperature at high strains on fatigue behavior of SAP alloys

      DEFF Research Database (Denmark)

      Blucher, J.T.; Knudsen, Per; Grant, N.J.

      1968-01-01

      Fatigue behavior of three SAP alloys of two nominal compositions (7 and 13% Al2O3) was studied in terms of strain rate and temperature at high strains; strain rate had no effect on life at 80 F, but had increasingly greater effect with increasing temperature above 500 F; life decreased with decre......Fatigue behavior of three SAP alloys of two nominal compositions (7 and 13% Al2O3) was studied in terms of strain rate and temperature at high strains; strain rate had no effect on life at 80 F, but had increasingly greater effect with increasing temperature above 500 F; life decreased...

    16. Surface instabilities during straining of anisotropic materials

      DEFF Research Database (Denmark)

      Legarth, Brian Nyvang; Richelsen, Ann Bettina

      2006-01-01

      The development of instabilities in traction-free surfaces is investigated numerically using a unit cell model. Full finite strain analyses are conducted using isotropic as well as anisotropic yield criteria and both plane strain tension and compression are considered. In the load range of tensio...... of principal overall strain. For other orientations surface instabilities are seen when non-associated plastic flow is taken into account. Compared to tension, smaller compressive deformations are needed in order to initiate a surface instability....

    17. Strain comparisons in aquaculture species: a manual

      OpenAIRE

      Ponzoni, R.W.; James, J.W.; Nguyen, N.H.; Mekkawy, W.; Khaw, H.L.

      2013-01-01

      When different strains or breeds of a particular species are available, the best choice is seldom immediately obvious for producers. Scientists are also interested in the relative performance of different strains because it provides a basis for recommendations to producers and it often stimulates the conduct of work aimed at unraveling the underlying biological mechanisms involved in the expression of such differences. Hence, strain or breed comparisons of some sort are frequently conducted. ...

    18. Hubungan Kecanduan Bermain Video Games Kekerasan dengan Perilaku Agresif pada Murid Laki-laki Kelas IV dan V di SD Negeri 02 Cupak Tangah Pauh Kota Padang

      Directory of Open Access Journals (Sweden)

      Rivo Armanda Satria

      2015-01-01

      Full Text Available AbstrakPerilaku agresif adalah perilaku yang bertujuan untuk menyakiti orang lain, untuk mengekspresikan perasaan negatifnya seperti permusuhan untuk mencapai tujuan yang diinginkan. Terdapat 4 aspek agresivitas, yaitu kemarahan, permusuhan, agresi verbal, dan agresi fisik. Salah satu faktor yang diduga mempengaruhi perilaku agresif adalah kebiasaan bermain video games yang mengandung unsur kekerasan. Tujuan penelitian ini adalah untuk mengetahui hubungan perilaku kecanduan bermain video games yang mengandung unsur kekerasan terhadap prilaku agresif pada murid laki-laki kelas IV dan V di SD Negeri 02 Cupak Tangah Pauh Kota Padang Tahun 2014. Penelitian ini menggunakan disain cross sectional study dengan jumlah sampel sebanyak 83 orang murid laki-laki dari kelas IV dan V di SD N 02 Cupak Tangah Pauh. Data dikumpulkan melalui wawancara kepada responden menggunakan kuesioner yang kemudian di analisis dengan uji statistik chi-square dengan derajat kepercayaan 95% (0,05.Hasil penelitian menunjukkan persentase responden yang memiliki perilaku agresif lebih tinggi pada responden yang mengalami kecanduan bermain video games yang mengandung unsur kekerasan jika dibandingkan dengan responden yang tidak mengalami kecanduan bermain video games yang mengandung unsur kekerasan (67,6%:20,4% dan terdapat hubungan yang bermakna antara kecanduan bermain video games yang mengandung unsur kekerasan dengan perilaku agresif (p-value=0,000.Disarankan bagi pihak sekolah agar memiliki program konseling psikologis anak misalnya dalam bentuk UKESWA (usaha kesehatan jiwa yang termasuk dalam program UKS (usaha kesehatan sekolah untuk mendeteksi sejak dini perilaku kecanduan anak terhadap video games yang mengandung unsur kekerasan dan perilaku agresif anak sehingga dapat diberikan bimbingan untuk mengatasi kecanduan dan perilaku agresif tersebut agar tidak berlanjut dan menjadi conduct disorder atau perilaku anti sosialKata kunci : agresif, kecanduan, video games

    19. Rat strains differ in susceptibility to Ureaplasma parvum-induced urinary tract infection and struvite stone formation.

      Science.gov (United States)

      Reyes, Leticia; Reinhard, Mary; O'donell, L J; Stevens, Janet; Brown, Mary B

      2006-12-01

      Individuals with struvite uroliths are susceptible to recurrent urinary tract infections (UTI), sepsis, and renal disease. Unfortunately, little is known about the host-specific factors that predispose to this disease. In order to develop a rodent model that can address this problem, we inoculated female Fischer 344 (F344), Lewis (LEW), Sprague-Dawley (SD), and Wistar (WIS) rats with a host-adapted strain of Ureaplasma parvum. Animals were necropsied at 2 weeks postinoculation; 100% of F344, 42% of SD, 10% of LEW, and 10% of WIS rats remained infected. Severe bladder lesions and struvite calculi were seen in 64% of F344 rats; in other rat strains, bladder lesions were mild or absent. F344 rats with struvite uroliths had the highest urinary levels of proinflammatory cytokines, such as GRO/KC, interleukin-1alpha (IL-1alpha), and IL-1beta. F344 rats without struvite stones at necropsy had milder bladder lesions and significantly lower urinary levels of proinflammatory cytokines but a more prominent inflammatory response than did other rat strains. Based on our results, struvite stone formation is linked to a robust inflammatory response that does not resolve UTI but instead promotes damage to surrounding tissues.

    20. Rat Strains Differ in Susceptibility to Ureaplasma parvum-Induced Urinary Tract Infection and Struvite Stone Formation▿

      Science.gov (United States)

      Reyes, Leticia; Reinhard, Mary; O'Donell, L. J.; Stevens, Janet; Brown, Mary B.

      2006-01-01

      Individuals with struvite uroliths are susceptible to recurrent urinary tract infections (UTI), sepsis, and renal disease. Unfortunately, little is known about the host-specific factors that predispose to this disease. In order to develop a rodent model that can address this problem, we inoculated female Fischer 344 (F344), Lewis (LEW), Sprague-Dawley (SD), and Wistar (WIS) rats with a host-adapted strain of Ureaplasma parvum. Animals were necropsied at 2 weeks postinoculation; 100% of F344, 42% of SD, 10% of LEW, and 10% of WIS rats remained infected. Severe bladder lesions and struvite calculi were seen in 64% of F344 rats; in other rat strains, bladder lesions were mild or absent. F344 rats with struvite uroliths had the highest urinary levels of proinflammatory cytokines, such as GRO/KC, interleukin-1α (IL-1α), and IL-1β. F344 rats without struvite stones at necropsy had milder bladder lesions and significantly lower urinary levels of proinflammatory cytokines but a more prominent inflammatory response than did other rat strains. Based on our results, struvite stone formation is linked to a robust inflammatory response that does not resolve UTI but instead promotes damage to surrounding tissues. PMID:16982825

    1. Characterization of Changes in Global Genes Expression in the Distal Colon of Loperamide-Induced Constipation SD Rats in Response to the Laxative Effects of Liriope platyphylla.

      Directory of Open Access Journals (Sweden)

      Ji Eun Kim

      Full Text Available To characterize the changes in global gene expression in the distal colon of constipated SD rats in response to the laxative effects of aqueous extracts of Liriope platyphylla (AEtLP, including isoflavone, saponin, oligosaccharide, succinic acid and hydroxyproline, the total RNA extracted from the distal colon of AEtLP-treated constipation rats was hybridized to oligonucleotide microarrays. The AEtLP treated rats showed an increase in the number of stools, mucosa thickness, flat luminal surface thickness, mucin secretion, and crypt number. Overall, compared to the controls, 581 genes were up-regulated and 216 genes were down-regulated by the constipation induced by loperamide in the constipated rats. After the AEtLP treatment, 67 genes were up-regulated and 421 genes were down-regulated. Among the transcripts up-regulated by constipation, 89 were significantly down-regulated and 22 were recovered to the normal levels by the AEtLP treatment. The major genes in the down-regulated categories included Slc9a5, klk10, Fgf15, and Alpi, whereas the major genes in the recovered categories were Cyp2b2, Ace, G6pc, and Setbp1. On the other hand, after the AEtLP treatment, ten of these genes down-regulated by constipation were up-regulated significantly and five were recovered to the normal levels. The major genes in the up-regulated categories included Serpina3n, Lcn2 and Slc5a8, whereas the major genes in the recovered categories were Tmem45a, Rerg and Rgc32. These results indicate that several gene functional groups and individual genes as constipation biomarkers respond to an AEtLP treatment in constipated model rats.

    2. The Effect of Propiconazole and Protective Effects of Selenium Gene Expression Profile of Caspase 9 in the Testicular Tissue of Male Sprague Dawley (SD Rats

      Directory of Open Access Journals (Sweden)

      S Rashidi pouya

      2016-08-01

      Full Text Available Background & aim: Conazoles including imidazoles or triazoles are anti- fungal agents widely used to prevent fungal growth and their infections. Propiconazole placed in this group is a systemic fungicide used widely for detoxification of cereal seeds especially rice in Iran and other countries. This fungicide were designed to inhibit a specific cytochrome P450, CYP51 (lanosterol-14-α- demethylase, a critical step in the biosynthesis of ergosterol, a steroid required for the formation of the fungal cell wall. In the present experimental study, the effect of propiconazole on Caspase 9 gene expression profile as an initiator of apoptotic process and protective effect of selenium were investigated. Methods: Forty SD rats were divided into 10 groups of 4,  including : control , sham1 (solvent of propiconazole, distilled water, sham 2 (solvent of selenium, normal saline and 1 group received 0.5 mg/kg selenium ,3 groups received propiconazole in doses of 10,50,75  mg/kg and 3 groups received propiconazole in doses of 10,50,75 mg/kg propiconazole with 0.5 mg/kg of selenium. Injections were intrapritoneal for two weeks in alternate days. Then, using RT-PCR and Total Lab program gene expression of caspase-9 testicular of all groups were studied. Data were analyzed using descriptive statistics. Results:  A significant increase of caspase 9 expression were observed among all experimental groups compared to control and sham groups. These findings indicated that 0.5 mg/kg selenium is not a suitable dose to create protection in this experimental study.  Conclusion: The significant increase in Caspase 9 gene expression profile observed in all experimental groups as compared to control suggests activation of apoptosis and inefficacy of selenium to protect the testis against induced damages.

    3. Molecular Weight Dependent Glucose Lowering Effect of Low Molecular Weight Chitosan Oligosaccharide (GO2KA1 on Postprandial Blood Glucose Level in SD Rats Model

      Directory of Open Access Journals (Sweden)

      Emmanouil Apostolidis

      2013-07-01

      Full Text Available This research investigated the effect of enzymatically digested low molecular weight (MW chitosan oligosaccharide on type 2 diabetes prevention. Three different chitosan oligosaccharide samples with varying MW were evaluated in vitro for inhibition of rat small intestinal α-glucosidase and porcine pancreatic α-amylase (GO2KA1; 10,000 Da. The in vitro results showed that all tested samples had similar rat α-glucosidase inhibitory and porcine α-amylase inhibitory activity. Based on these observations, we decided to further investigate the effect of all three samples at a dose of 0.1 g/kg, on reducing postprandial blood glucose levels in Sprague-Dawley (SD rat model after sucrose loading test. In the animal trial, all tested samples had postprandial blood glucose reduction effect, when compared to control, however GO2KA1 supplementation had the strongest effect. The glucose peak (Cmax for GO2KA1 and control was 152 mg/dL and 193 mg/dL, respectively. The area under the blood glucose-time curve (AUC for GO2KA1 and control was 262 h mg/dL and 305 h mg/dL, respectively. Furthermore, the time of peak plasma concentration of blood glucose (Tmax for GO2KA1 was significantly delayed (0.9 h compared to control (0.5 h. These results suggest that GO2KA1 could have a beneficial effect for blood glucose management relevant to diabetes prevention in normal and pre-diabetic individuals. The suggested mechanism of action is via inhibition of the carbohydrate hydrolysis enzyme α-glucosidase and since GO2KA1 (MW < 1000 Da had higher in vivo effect, we hypothesize that it is more readily absorbed and might exert further biological effect once it is absorbed in the blood stream, relevant to blood glucose management.

    4. [Characteristics of Lactobacillus strains contained in pharmaceuticals].

      Science.gov (United States)

      Banach, W; Bucholc, B; Wójcik, B

      2001-01-01

      The aim of the study was to characterize lactic acid bacteria (LAB) which are components of drugs administered orally in cases of intestinal disturbances, or antibiotic--related diarrhea. Biochemical properties, growth behavior, bile tolerance, and survival at low pH of six LAB strains (four strains L. rhamnosus and two L. acidophilus) were studied. The survival at low pH was determined in MRS broth (Difco) acidified to pH 1; 2; 3; and 4. Bile tolerance was tested on MRS broth with 0.3% oxgall (Difco). Between tested strains differences in ability to grow at low pH and survival in bile were observed. Only 0.01% inoculum of all examined strains survived at pH 1. Differences between strains in survival at low pH (pH 2 and pH 3) and tolerance of bile were observed. However, after 2 h incubation at pH 4, 100% of strains stayed alive. Examined strains demonstrated good 3% bile tolerance. All strains met the criteria for probiotic strains: ability to survive at pH 3 and in the presence of bile.

    5. Properties of strain gages at cryogenic temperature

      International Nuclear Information System (INIS)

      Shibata, Nobuo; Fujiyoshi, Toshimitsu.

      1978-01-01

      At the time of developing superconduction generators, the stress measurement for rotor parts is required to grasp the safety and performance of the rotor at cryogenic temperature, which is cooled with liquid helium. In case of carrying out the stress measurement with strain gages, the problems are as follows. The strain gages and lead wires are exposed to cryogenic temperature from 4 to 10 K and strong magnetic field of about 3T, and subjected to high centrifugal acceleration of about 500G. In order to establish the techniques of the stress measurement under such conditions, the adhesives and damp-proof coatings for strain gages and strain gages themselves in Japan and foreign countries were examined on the properties at cryogenic temperature. As for the properties of strain gages, mainly the apparent strain owing to temperature change was investigated, and the change of the gage factors was studies only at liquid nitrogen temperature. The stress measurement with strain gages at low temperature had been studied in detail down to liquid nitrogen temperature concerning LNG tanks. The experimental apparatus, the samples, the testing methods and the test results of cooling tests on adhesives and damp-proof coatings, and the temperature characteristics of strain gages are reported. The usable adhesives and coatings were found, and correction by accurate temperature measurement is required for apparent strain. (Kako, I.)

    6. Comparison of Thermal Creep Strain Calculation Results Using Time Hardening and Strain Hardening Rules

      International Nuclear Information System (INIS)

      Kim, Junehyung; Cheon, Jinsik; Lee, Byoungoon; Lee, Chanbock

      2014-01-01

      One of the design criteria for the fuel rod in PGSFR is the thermal creep strain of the cladding, because the cladding is exposed to a high temperature for a long time during reactor operation period. In general, there are two kind of calculation scheme for thermal creep strain: time hardening and strain hardening rules. In this work, thermal creep strain calculation results for HT9 cladding by using time hardening and strain hardening rules are compared by employing KAERI's current metallic fuel performance analysis code, MACSIS. Also, thermal creep strain calculation results by using ANL's metallic fuel performance analysis code, LIFE-METAL which adopts strain hardening rule are compared with those by using MACSIS. Thermal creep strain calculation results for HT9 cladding by using time hardening and strain hardening rules were compared by employing KAERI's current metallic fuel performance analysis code, MACSIS. Also, thermal creep strain calculation results by using ANL's metallic fuel performance analysis code, LIFE-METAL which adopts strain hardening rule were compared with those by using MACSIS. Tertiary creep started earlier in time hardening rule than in strain hardening rule. Also, calculation results by MACSIS with strain hardening and those obtained by using LIFE-METAL were almost identical to each other

    7. Predicting creep rupture from early strain data

      International Nuclear Information System (INIS)

      Holmstroem, Stefan; Auerkari, Pertti

      2009-01-01

      To extend creep life modelling from classical rupture modelling, a robust and effective parametric strain model has been developed. The model can reproduce with good accuracy all parts of the creep curve, economically utilising the available rupture models. The resulting combined model can also be used to predict rupture from the available strain data, and to further improve the rupture models. The methodology can utilise unfailed specimen data for life assessment at lower stress levels than what is possible from rupture data alone. Master curves for creep strain and rupture have been produced for oxygen-free phosphorus-doped (OFP) copper with a maximum testing time of 51,000 h. Values of time to specific strain at given stress (40-165 MPa) and temperature (125-350 deg. C) were fitted to the models in the strain range of 0.1-38%. With typical inhomogeneous multi-batch creep data, the combined strain and rupture modelling involves the steps of investigation of the data quality, extraction of elastic and creep strain response, rupture modelling, data set balancing and creep strain modelling. Finally, the master curves for strain and rupture are tested and validated for overall fitting efficiency. With the Wilshire equation as the basis for the rupture model, the strain model applies classical parametric principles with an Arrhenius type of thermal activation and a power law type of stress dependence for the strain rate. The strain model also assumes that the processes of primary and secondary creep can be reasonably correlated. The rupture model represents a clear improvement over previous models in the range of the test data. The creep strain information from interrupted and running tests were assessed together with the rupture data investigating the possibility of rupture model improvement towards lower stress levels by inverse utilisation of the combined rupture based strain model. The developed creep strain model together with the improved rupture model is

    8. Conduction band structure and electron mobility in uniaxially strained Si via externally applied strain in nanomembranes

      Energy Technology Data Exchange (ETDEWEB)

      Chen Feng [Xi' an Jiaotong University, Xi' an, Shaanxi 710049 (China); Euaruksakul, Chanan; Himpsel, F J; Lagally, Max G [University of Wisconsin-Madison, Madison, WI 53706 (United States); Liu Zheng; Liu Feng, E-mail: lagally@engr.wisc.edu [University of Utah, Salt Lake City, UT 84112 (United States)

      2011-08-17

      Strain changes the band structure of semiconductors. We use x-ray absorption spectroscopy to study the change in the density of conduction band (CB) states when silicon is uniaxially strained along the [1 0 0] and [1 1 0] directions. High stress can be applied to silicon nanomembranes, because their thinness allows high levels of strain without fracture. Strain-induced changes in both the sixfold degenerate {Delta} valleys and the eightfold degenerate L valleys are determined quantitatively. The uniaxial deformation potentials of both {Delta} and L valleys are directly extracted using a strain tensor appropriate to the boundary conditions, i.e., confinement in the plane in the direction orthogonal to the straining direction, which correspond to those of strained CMOS in commercial applications. The experimentally determined deformation potentials match the theoretical predictions well. We predict electron mobility enhancement created by strain-induced CB modifications.

    9. SD118-Xanthocillin X (1, a Novel Marine Agent Extracted from Penicillium commune, Induces Autophagy through the Inhibition of the MEK/ERK Pathway

      Directory of Open Access Journals (Sweden)

      Caiguo Huang

      2012-06-01

      Full Text Available A compound named SD118-xanthocillin X (1 (C18H12N2O2, isolated from Penicillium commune in a deep-sea sediment sample, has been shown to inhibit the growth of several cancer cell lines in vitro. In the present study, we employed a growth inhibition assay and apoptotic analysis to identify the biological effect and detailed mechanism of SD118-xanthocillin X (1 in human hepatocellular carcinoma (HepG2 cells. SD118-xanthocillin X (1 demonstrated a concentration-dependent inhibitory effect on the growth of HepG2 cells and caused slight cellular apoptosis and significantly induced autophagy. Autophagy was detected as early as 12 h by the conversion of microtubule-associated protein 1 light chain 3 (LC3-I to LC3-II, following cleavage and lipid addition to LC3-I. The pharmacological autophagy inhibitor 3-methyladenine largely attenuates the growth inhibition and autophagic effect of SD118-xanthocillin X (1 in HepG2 cells. Our data also indicated that the autophagic effect of SD118-xanthocillin X (1 occurs via the down-regulation of the MEK/ERK signaling pathway and the up-regulated class III PI3K/Beclin 1 signaling pathway.

    10. Nanocomposite Strain Gauges Having Small TCRs

      Science.gov (United States)

      Gregory, Otto; Chen, Ximing

      2009-01-01

      Ceramic strain gauges in which the strain-sensitive electrically conductive strips made from nanocomposites of noble metal and indium tin oxide (ITO) are being developed for use in gas turbine engines and other power-generation systems in which gas temperatures can exceed 1,500 F (about 816 C). In general, strain gauges exhibit spurious thermally induced components of response denoted apparent strain. When temperature varies, a strain-gauge material that has a nonzero temperature coefficient of resistance (TCR) exhibits an undesired change in electrical resistance that can be mistaken for the change in resistance caused by a change in strain. It would be desirable to formulate straingauge materials having TCRs as small as possible so as to minimize apparent strain. Most metals exhibit positive TCRs, while most semiconductors, including ITO, exhibit negative TCRs. The present development is based on the idea of using the negative TCR of ITO to counter the positive TCRs of noble metals and of obtaining the benefit of the ability of both ITO and noble metals to endure high temperatures. The noble metal used in this development thus far has been platinum. Combinatorial libraries of many ceramic strain gauges containing nanocomposites of various proportions of ITO and platinum were fabricated by reactive co-sputtering from ITO and platinum targets onto alumina- and zirconia-based substrates mounted at various positions between the targets.

    11. Strain differentiation of polioviruses with monoclonal antibodies.

      NARCIS (Netherlands)

      A.D.M.E. Osterhaus (Albert); A.L. van Wezel; A.J.H. Stegmann; J.A.A.M. van Asten (Jack)

      1984-01-01

      textabstractPanels of monoclonal antibodies raised against different poliovirus type 1, 2 and 3 strains, were tested in a micro-neutralization test and in a micro-enzyme linked immunosorbent assay against a large number of poliovirus strains. The results were compared with those obtained with the

    12. Organic metabolites produced by Vibrio parahaemolyticus strain ...

      African Journals Online (AJOL)

      Identification and action of several antibacterial metabolites produced by a fish pathogen Vibrio parahaemolyticus strain An3 from marine ecosystem of Goa has been demonstrated. Antibacterial activity of the crude cell extract of the test bacterium has been evaluated against indicator pathogenic bacterial strains such as ...

    13. On lower order strain gradient plasticity theories

      DEFF Research Database (Denmark)

      Niordson, Christian Frithiof; Hutchinson, J. W.

      2002-01-01

      By way of numerical examples, this paper explores the nature of solutions to a class of strain gradient plasticity theories that employ conventional stresses, equilibrium equations and boundary conditions. Strain gradients come into play in these modified conventional theories only to alter...

    14. Job strain and time to pregnancy

      DEFF Research Database (Denmark)

      Hjollund, N H; Kold Jensen, T; Bonde, Jens Peter

      1998-01-01

      The association between fertility and job strain defined as high job demands and low job control has not previously been studied. A follow-up study was conducted with prospective collection of information on job strain among women, achievement of pregnancy, and potential confounding variables....

    15. Medically Complex Home Care and Caregiver Strain

      Science.gov (United States)

      Moorman, Sara M.; Macdonald, Cameron

      2013-01-01

      Purpose of the study: To examine (a) whether the content of caregiving tasks (i.e., nursing vs. personal care) contributes to variation in caregivers' strain and (b) whether the level of complexity of nursing tasks contributes to variation in strain among caregivers providing help with such tasks. Design and methods: The data came from the Cash…

    16. Five challenges in modelling interacting strain dynamics

      DEFF Research Database (Denmark)

      Wikramaratna, Paul S; Kurcharski, Adam; Gupta, Sunetra

      2015-01-01

      population models. Next we consider the nature of so-called “strain space”. We describe two key types of host heterogeneities, and explain how models could help generate a better understanding of their effects. Finally, for diseases with many strains, we consider the challenge of modelling how immunity...

    17. Multiple Genome Sequences of Lactobacillus plantarum Strains

      OpenAIRE

      Kafka, Thomas A.; Geissler, Andreas J.; Vogel, Rudi F.

      2017-01-01

      ABSTRACT We report here the genome sequences of four Lactobacillus plantarum strains which vary in surface hydrophobicity. Bioinformatic analysis, using additional genomes of Lactobacillus plantarum strains, revealed a possible correlation between the cell wall teichoic acid-type and cell surface hydrophobicity and provide the basis for consecutive analyses.

    18. Preliminary characterization of slow growing rhizobial strains ...

      African Journals Online (AJOL)

      In this paper, we did some preliminary characterization of six slow growing rhizobial strains, isolated from Retama monosperma (L.) Boiss. root nodules sampled from 3 sites along the coast of Oran (CapeFalcon, Bousfer and MersElHadjadj) in Northwestern Algeria. Results of this study showed that all strains had a very ...

    19. Typing of lymphogranuloma venereum Chlamydia trachomatis strains

      NARCIS (Netherlands)

      Christerson, Linus; de Vries, Henry J. C.; de Barbeyrac, Bertille; Gaydos, Charlotte A.; Henrich, Birgit; Hoffmann, Steen; Schachter, Julius; Thorvaldsen, Johannes; Vall-Mayans, Martí; Klint, Markus; Herrmann, Björn; Morré, Servaas A.

      2010-01-01

      We analyzed by multilocus sequence typing 77 lymphogranuloma venereum Chlamydia trachomatis strains from men who have sex with men in Europe and the United States. Specimens from an outbreak in 2003 in Europe were monoclonal. In contrast, several strains were in the United States in the 1980s,

    20. Typing of Lymphogranuloma Venereum Chlamydia trachomatis Strains

      Science.gov (United States)

      Christerson, Linus; de Vries, Henry J.C.; de Barbeyrac, Bertille; Gaydos, Charlotte A.; Henrich, Birgit; Hoffmann, Steen; Schachter, Julius; Thorvaldsen, Johannes; Vall-Mayans, Martí; Klint, Markus; Morré, Servaas A.

      2010-01-01

      We analyzed by multilocus sequence typing 77 lymphogranuloma venereum Chlamydia trachomatis strains from men who have sex with men in Europe and the United States. Specimens from an outbreak in 2003 in Europe were monoclonal. In contrast, several strains were in the United States in the 1980s, including a variant from Europe. PMID:21029543