WorldWideScience

Sample records for steady-state mass transfer

  1. Analytical solution and simplified analysis of coupled parent-daughter steady-state transport with multirate mass transfer

    Science.gov (United States)

    R. Haggerty

    2013-01-01

    In this technical note, a steady-state analytical solution of concentrations of a parent solute reacting to a daughter solute, both of which are undergoing transport and multirate mass transfer, is presented. Although the governing equations are complicated, the resulting solution can be expressed in simple terms. A function of the ratio of concentrations, In (daughter...

  2. the steady-state performance characteristics of single phase transfer

    African Journals Online (AJOL)

    2012-11-03

    Nov 3, 2012 ... The paper reports the derivation of the steady- state equivalent circuit of a single phase transfer ... series opposition between the two halves of the ma- ..... from its equivalent circuit of fig 6 for different values of slip. Impedance due to forward field. Zf = Rf + jXf = Rr. 2(2s - 1). + jxr. 2. (19) in parallel with jxm. 2.

  3. Calibration of a mass spectrometer in steady-state conditions

    International Nuclear Information System (INIS)

    Popov, E.V.; Kupryazhkin, A.Ya.

    1982-01-01

    The mass spectrometer calibration technique by 4 He in steady-state operation conditions by the method of gas expansion from the small volume into the large one using a capacitance micromanometer is described. For realizing steady-state operation of the mass-spectrometer one of the steam-mercury diffusion pumps has been replaced for an adsorption pump. Using adsorption pump permits to maintain working vacuum in the system for more than 3 h. The mass spectrometer calibration has been performed by comparing calibrated volume and mass spectrometer chamber volume. The mass spectrometer sensitivity value by 4 He in the steady-state operation ν=(4.1+-0.1)x10 - 7 Pa/mV is obtained

  4. Non-steady-state heat transfer of finned surface

    International Nuclear Information System (INIS)

    Okamoto, Y.; Kameoka, T.

    1974-01-01

    For many purposes, the finned surface is being used to increase heat transfer. Heat exchangers and fuel elements of gas cooled nuclear reactors require the use of the finned surface for high flux heat transfer. The problem is analytically treated by deriving a non-steady-state equation of radiative and convective heat transfer of annular and radial fins in case of sudden change of the fin-root temperature or heat flux. The numerical solution of temperature distribution along the fin is obtained for several typical transient cases. (U.S.)

  5. Characterizing the relationship between steady state and response using analytical expressions for the steady states of mass action models.

    Science.gov (United States)

    Loriaux, Paul Michael; Tesler, Glenn; Hoffmann, Alexander

    2013-01-01

    The steady states of cells affect their response to perturbation. Indeed, diagnostic markers for predicting the response to therapeutic perturbation are often based on steady state measurements. In spite of this, no method exists to systematically characterize the relationship between steady state and response. Mathematical models are established tools for studying cellular responses, but characterizing their relationship to the steady state requires that it have a parametric, or analytical, expression. For some models, this expression can be derived by the King-Altman method. However, King-Altman requires that no substrate act as an enzyme, and is therefore not applicable to most models of signal transduction. For this reason we developed py-substitution, a simple but general method for deriving analytical expressions for the steady states of mass action models. Where the King-Altman method is applicable, we show that py-substitution yields an equivalent expression, and at comparable efficiency. We use py-substitution to study the relationship between steady state and sensitivity to the anti-cancer drug candidate, dulanermin (recombinant human TRAIL). First, we use py-substitution to derive an analytical expression for the steady state of a published model of TRAIL-induced apoptosis. Next, we show that the amount of TRAIL required for cell death is sensitive to the steady state concentrations of procaspase 8 and its negative regulator, Bar, but not the other procaspase molecules. This suggests that activation of caspase 8 is a critical point in the death decision process. Finally, we show that changes in the threshold at which TRAIL results in cell death is not always equivalent to changes in the time of death, as is commonly assumed. Our work demonstrates that an analytical expression is a powerful tool for identifying steady state determinants of the cellular response to perturbation. All code is available at http://signalingsystems.ucsd.edu/models-and-code/ or

  6. Locating CVBEM collocation points for steady state heat transfer problems

    Science.gov (United States)

    Hromadka, T.V.

    1985-01-01

    The Complex Variable Boundary Element Method or CVBEM provides a highly accurate means of developing numerical solutions to steady state two-dimensional heat transfer problems. The numerical approach exactly solves the Laplace equation and satisfies the boundary conditions at specified points on the boundary by means of collocation. The accuracy of the approximation depends upon the nodal point distribution specified by the numerical analyst. In order to develop subsequent, refined approximation functions, four techniques for selecting additional collocation points are presented. The techniques are compared as to the governing theory, representation of the error of approximation on the problem boundary, the computational costs, and the ease of use by the numerical analyst. ?? 1985.

  7. Dispersed-flow film boiling in rod-bundle geometry: steady-state heat-transfer data and correlation comparisons

    International Nuclear Information System (INIS)

    Yoder, G.L.; Morris, D.G.; Mullins, C.B.; Ott, L.J.; Reed, D.A.

    1982-03-01

    Assessment of six film boiling correlations and one single-phase vapor correlation has been made using data from 22 steady state upflow rod bundle tests (series 3.07.9). Bundle fluid conditions were calculated using energy and mass conservation considerations. Results of the steady state film boiling tests support the conclusions reached in the analysis of prior transient tests 3.03.6AR, 3.06.6B, and 3.08.6C. Comparisons between experimentally determined and correlation-predicted heat transfer coefficients, are presented

  8. Steady-state heat transfer in an inverted U-tube steam generator

    International Nuclear Information System (INIS)

    Boucher, T.J.

    1986-01-01

    Experimental results are presented involving U-tube steam generator tube bundle local heat transfer and fluid conditions during steady-state, full-power operations performed at high temperatures and pressures with conditions typical of a pressurized water reactor (15.0 MPa primary pressure, 600 K hot-leg fluid temperatures, 6.2 MPa secondary pressure). The MOD-2C facility represents the state-of-the-art in measurement of tube local heat transfer data and average tube bundle secondary fluid density at several elevations, which allows an estimate of the axial heat transfer and void distributions during steady-state and transient operations. The method of heat transfer data reduction is presented and the heat flux, secondary convective heat transfer coefficient, and void fraction distributions are quantified for steady-state, full-power operations

  9. Steady-state and transient heat transfer through fins of complex geometry

    Directory of Open Access Journals (Sweden)

    Taler Dawid

    2014-06-01

    Full Text Available Various methods for steady-state and transient analysis of temperature distribution and efficiency of continuous-plate fins are presented. For a constant heat transfer coefficient over the fin surface, the plate fin can be divided into imaginary rectangular or hexangular fins. At first approximate methods for determining the steady-state fin efficiency like the method of equivalent circular fin and the sector method are discussed. When the fin geometry is complex, thus transient temperature distribution and fin efficiency can be determined using numerical methods. A numerical method for transient analysis of fins with complex geometry is developed. Transient temperature distributions in continuous fins attached to oval tubes is computed using the finite volume - finite element methods. The developed method can be used in the transient analysis of compact heat exchangers to calculate correctly the heat flow rate transferred from the finned tubes to the fluid.

  10. Dispersed flow film boiling heat transfer of flowing water in vertical tubes: CIAE steady state data and prediction methods

    International Nuclear Information System (INIS)

    Chen Yuzhou; Chen Haiyan

    2000-01-01

    In CIAE a great number of film boiling experimental data have been obtained at steady state by using directly heated hot patch technique, covering the range of pressure 0.1-6MPa and mass flux of 23-1462 (23-500 mainly) kg/m 2 s. It is observed that in dispersed flow film boiling significant thermal nonequilibrium exists, and the heat transfer coefficients exhibit strongly history-dependent nature. Based on the experimental results a mechanistic model and a tabular method are proposed, and the assessment of RELAP5/MOD2.5 is made. (author)

  11. Mass, momentum, and energy flux conservation between linear and nonlinear steady-state wave groups

    Science.gov (United States)

    Liu, Zeng; Xu, Dali; Liao, Shijun

    2017-12-01

    This paper provides a mass, momentum, and energy flux conservation analysis between the linear and nonlinear steady-state wave groups. Convergent high-order solutions for nonlinear wave groups with multiple steady-state near resonances in deep water have been obtained by means of the homotopy analysis method. The small divisors associated with nearly resonant components are transformed to singularities that are originally caused by exact resonances by a piecewise auxiliary linear operator. Both two primary components and other nearly resonant ones are considered in the initial guess to search for finite amplitude wave groups. It is found that as nonlinearity of wave groups increases, more wave components appear in the spectrum due to the nearly resonant interactions. The nonlinear wave fields change from the initial bi-chromatic waves that contain only two nontrivial primary components into the steady-state resonant waves that contain both two primary components and other nearly resonant ones. The conservation of mean rates of mass, momentum, and energy fluxes is established between the nonlinear wave groups and linear waves that are combined by two primary components with the same frequencies as in nonlinear wave groups. Comparison of the linear and nonlinear wave fields shows that the nearly resonant components influence the wave field distribution significantly: the nonlinear free surfaces have more peaked crests, steeper troughs, and more flatten wave nodes, and the related velocities at the crests and troughs increase more rapidly with the nonlinearity. All of these findings are helpful to enrich and deepen our understanding about nonlinear wave groups.

  12. Quasi-steady-state voltammetry of rapid electron transfer reactions at the macroscopic substrate of the scanning electrochemical microscope.

    Science.gov (United States)

    Nioradze, Nikoloz; Kim, Jiyeon; Amemiya, Shigeru

    2011-02-01

    We report on a novel theory and experiment for scanning electrochemical microscopy (SECM) to enable quasi-steady-state voltammetry of rapid electron transfer (ET) reactions at macroscopic substrates. With this powerful approach, the substrate potential is cycled widely across the formal potential of a redox couple while the reactant or product of a substrate reaction is amperometrically detected at the tip in the feedback or substrate generation/tip collection mode, respectively. The plot of tip current versus substrate potential features the retraceable sigmoidal shape of a quasi-steady-state voltammogram although a transient voltammogram is obtained at the macroscopic substrate. Finite element simulations reveal that a short tip-substrate distance and a reversible substrate reaction (except under the tip) are required for quasi-steady-state voltammetry. Advantageously, a pair of quasi-steady-state voltammograms is obtained by employing both operation modes to reliably determine all transport, thermodynamic, and kinetic parameters as confirmed experimentally for rapid ET reactions of ferrocenemethanol and 7,7,8,8-tetracyanoquinodimethane at a Pt substrate with ∼0.5 μm-radius Pt tips positioned at 90 nm-1 μm distances. Standard ET rate constants of ∼7 cm/s were obtained for the latter mediator as the largest determined for a substrate reaction by SECM. Various potential applications of quasi-steady-state voltammetry are also proposed.

  13. Steady state phosphorus mass balance model during hemodialysis based on a pseudo one-compartment kinetic model.

    Science.gov (United States)

    Leypoldt, John K; Agar, Baris U; Akonur, Alp; Gellens, Mary E; Culleton, Bruce F

    2012-11-01

    Mathematical models of phosphorus kinetics and mass balance during hemodialysis are in early development. We describe a theoretical phosphorus steady state mass balance model during hemodialysis based on a novel pseudo one-compartment kinetic model. The steady state mass balance model accounted for net intestinal absorption of phosphorus and phosphorus removal by both dialysis and residual kidney function. Analytical mathematical solutions were derived to describe time-dependent intradialytic and interdialytic serum phosphorus concentrations assuming hemodialysis treatments were performed symmetrically throughout a week. Results from the steady state phosphorus mass balance model are described for thrice weekly hemodialysis treatment prescriptions only. The analysis predicts 1) a minimal impact of dialyzer phosphorus clearance on predialysis serum phosphorus concentration using modern, conventional hemodialysis technology, 2) variability in the postdialysis-to-predialysis phosphorus concentration ratio due to differences in patient-specific phosphorus mobilization, and 3) the importance of treatment time in determining the predialysis serum phosphorus concentration. We conclude that a steady state phosphorus mass balance model can be developed based on a pseudo one-compartment kinetic model and that predictions from this model are consistent with previous clinical observations. The predictions from this mass balance model are theoretical and hypothesis-generating only; additional prospective clinical studies will be required for model confirmation.

  14. Comparative analysis of steady state heat transfer in a TBC and ...

    Indian Academy of Sciences (India)

    - etry conforming to the NACA0012 is developed which is then used in a finite element algorithm to obtain a non-linear steady state solution to the heat equation for the blade under convection and radiation boundary conditions. The effects of.

  15. Post-CHF heat transfer during steady-state and transient conditions

    International Nuclear Information System (INIS)

    Fung, K.K.

    1978-06-01

    This review extends previous reviews of steady-state post-CHF literature by Groeneveld, Gardiner, and Fung by including more recent data. A review of the literature on transient post-CHF data is also included by extending the work of Yadigaroglu

  16. A principle for the noninvasive measurement of steady-state heat transfer parameters in living tissues

    Directory of Open Access Journals (Sweden)

    S. Yu. Makarov

    2014-01-01

    thermal field in biotissue (measuring procedure with the number i, dUiis a variation of a physical value U which unambiguously determines the steady-state thermal field, {pj} is a set of parameters to be measured.Theoretical analysis has shown that the implementation of the above principle leads to the equations that do not contain unknown values of blood temperature and power density of biological heat sources, unlike the starting Pennes equation [4]. This is the main advantage of the developed approach in comparison with non-stationary methods. In addition, there is no dynamic measurement error which is inevitably associated with the measurement procedure for the transient processes.Numerical and physical experiments have been carried out to validate the functionality of the above principle for noninvasive measuring the parameters of stationary heat transfer. For example, with use a thermophysical model of biological tissue [5] the procedure of measuring was simulated to obtain the values of two thermophysical parameters of model biological tissue, namely the blood perfusion (in absolute units and the thermal conductivity. Also, with use a specially designed probe the measurements were carried out for the natural biological tissue of human skin epithelium. The blood perfusion parameter estimation value is in good agreement with the literature data [6], despite the illustrative purpose of conducted measurements. These experiments have also demonstrated the possibility of simultaneous measuring the several thermophysical properties of biological tissue in a noninvasive manner, using a rather simple equipment.Formula (1 can contain not only thermophysical parameters of the living tissue, but any other parameters provided that each one unambiguously affects the heat transfer in a particular experiment. For example, it was shown that it is possible to recover the thicknesses of subcutaneous tissue layers of model of skin on the results of thermal measurements on the basis of

  17. Heat transfer and voidage measurements in steady state post-dryout at low quality and high pressure

    International Nuclear Information System (INIS)

    Savage, R.A.; Archer, D.; Swinnerton, D.

    1992-01-01

    Steady state post-dryout heat transfer and voidage data have been obtained at pressures up to 70 bar and flows up to 1000 kg/m 2 s inside a vertical tube. The data were obtained with steam/water using a directly heated hot notch test section. Heat flux and voidage data are presented. The data are used to investigate aspects of the TRAC-PF1/MOD2 version 5.3 reflood model and are compared against heat transfer models used in it. (8 figures) (Author)

  18. Steady state analysis of Energy Transfer Control (ETC) and compressor bleed concepts of remote lift fan control

    Science.gov (United States)

    Sellers, J. F.

    1973-01-01

    Two new concepts of control for VTOL aircraft remote lift fans are analyzed and discussed. Both concepts employ flow transfer among lift fans located in separate parts of the aircraft in order to obtain attitude control moments in hover and low-speed flight. The results presented are from a digital computer analysis of the YJ97/LF460 remote drive turbofan, although qualitative conclusions should apply to any remote fan system. The basic operating principles of the two systems are described, and their steady-state moment generating capabilities are discussed. Lift-recovery strategies for component failures are also analyzed.

  19. Replacement of unsteady heat transfer coefficient by equivalent steady-state one when calculating temperature oscillations in a thermal layer

    Science.gov (United States)

    Supel'nyak, M. I.

    2017-11-01

    Features of calculation of temperature oscillations which are damped in a surface layer of a solid and which are having a small range in comparison with range of temperature of the fluid medium surrounding the solid at heat transfer coefficient changing in time under the periodic law are considered. For the specified case the equations for approximate definition of constant and oscillating components of temperature field of a solid are received. The possibility of use of appropriately chosen steady-state coefficient when calculating the temperature oscillations instead of unsteady heat-transfer coefficient is investigated. Dependence for definition of such equivalent constant heat-transfer coefficient is determined. With its help the research of temperature oscillations of solids with canonical form for some specific conditions of heat transfer is undertaken. Comparison of the obtained data with results of exact solutions of a problem of heat conductivity by which the limits to applicability of the offered approach are defined is carried out.

  20. Using bioprocess stoichiometry to build a plant-wide mass balance based steady-state WWTP model.

    Science.gov (United States)

    Ekama, G A

    2009-05-01

    Steady-state models are useful for design of wastewater treatment plants (WWTPs) because they allow reactor sizes and interconnecting flows to be simply determined from explicit equations in terms of unit operation performance criteria. Once the overall WWTP scheme is established and the main system defining parameters of the individual unit operations estimated, dynamic models can be applied to the connected unit operations to refine their design and evaluate their performance under dynamic flow and load conditions. To model anaerobic digestion (AD) within plant-wide WWTP models, not only COD and nitrogen (N) but also carbon (C) fluxes entering the AD need to be defined. Current plant-wide models, like benchmark simulation model No 2 (BSM2), impose a C flux at the AD influent. In this paper, the COD and N mass balance steady-state models of activated sludge (AS) organics degradation, nitrification and denitrification (ND) and anaerobic (AD) and aerobic (AerD) digestion of wastewater sludge are extended and linked with bioprocess transformation stoichiometry to form C, H, O, N, chemical oxygen demand (COD) and charge mass balance based models so that also C (and H and O) can be tracked through the whole WWTP. By assigning a stoichiometric composition (x, y, z and a in C(x)H(y)O(z)N(a)) to each of the five main influent wastewater organic fractions and ammonia, these, and the products generated from them via the biological processes, are tracked through the WWTP. The model is applied to two theoretical case study WWTPs treating the same raw wastewater (WW) to the same final sludge residual biodegradable COD. It is demonstrated that much useful information can be generated with the relatively simple steady-state models to aid WWTP layout design and track the different products exiting the WWTP via the solid, liquid and gas streams, such as aerobic versus anaerobic digestion of waste activated sludge, N loads in recycle streams, methane production for energy recovery

  1. Steady-state domain wall motion driven by adiabatic spin-transfer torque with assistance of microwave field

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Xi-guang; Guo, Guang-hua, E-mail: guogh@mail.csu.edu.cn; Nie, Yao-zhuang; Xia, Qing-lin; Tang, Wei [School of Physics and Electronics, Central South University, Changsha 410083 (China); Wang, D. [Department of Physics, National University of Defense Technology, Changsha 410073 (China); Zeng, Zhong-ming [Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, Suzhou 215123 (China)

    2013-12-23

    We have studied the current-induced displacement of a 180° Bloch wall by means of micromagnetic simulation and analytical approach. It is found that the adiabatic spin-transfer torque can sustain a steady-state domain wall (DW) motion in the direction opposite to that of the electron flow without Walker Breakdown when a transverse microwave field is applied. This kind of motion is very sensitive to the microwave frequency and can be resonantly enhanced by exciting the domain wall thickness oscillation mode. A one-dimensional analytical model was established to account for the microwave-assisted wall motion. These findings may be helpful for reducing the critical spin-polarized current density and designing DW-based spintronic devices.

  2. Mantle rare gas relative abundances in a steady-state mass transport model

    Science.gov (United States)

    Porcelli, D.; Wasserburg, G. J.

    1994-01-01

    A model for He and Xe was presented previously which incorporates mass transfer of rare gases from an undegassed lower mantle (P) and the atmosphere into a degassed upper mantle (D). We extend the model to include Ne and Ar. Model constraints on rare gas relative abundances within P are derived. Discussions of terrestrial volatile acquisition have focused on the rare gas abundance pattern of the atmosphere relative to meteoritic components, and the pattern of rare gases still trapped in the Ear,th is important in identifying volatile capture and loss processes operating during Earth formation. The assumptions and principles of the model are discussed in Wasserburg and Porcelli (this volume). For P, the concentrations in P of the decay/nuclear products 4 He, 21 Ne, 40 Ar, and 136 Xe can be calculated from the concentrations of the parent elements U, Th, K, and Pu. The total concentration of the daughter element in P is proportional to the isotopic shifts in P. For Ar, ((40)Ar/(36)Ar)p - ((40)Ar/(36)Ar)o =Delta (exp 40) p= 40 Cp/(exp 36)C where(i)C(sub j) the concentration of isotope i in j. In D, isotope compositions are the result of mixing rare gases from P, decay/nuclear products generated in the upper mantle, and subducted rare gases (for Ar and Xe).

  3. Non-steady state mass action dynamics without rate constants: dynamics of coupled reactions using chemical potentials

    Science.gov (United States)

    Cannon, William R.; Baker, Scott E.

    2017-10-01

    Comprehensive and predictive simulation of coupled reaction networks has long been a goal of biology and other fields. Currently, metabolic network models that utilize enzyme mass action kinetics have predictive power but are limited in scope and application by the fact that the determination of enzyme rate constants is laborious and low throughput. We present a statistical thermodynamic formulation of the law of mass action for coupled reactions at both steady states and non-stationary states. The formulation uses chemical potentials instead of rate constants. When used to model deterministic systems, the method corresponds to a rescaling of the time dependent reactions in such a way that steady states can be reached on the same time scale but with significantly fewer computational steps. The relationships between reaction affinities, free energy changes and generalized detailed balance are central to the discussion. The significance for applications in systems biology are discussed as is the concept and assumption of maximum entropy production rate as a biological principle that links thermodynamics to natural selection.

  4. Comparative analysis of steady state heat transfer in a TBC and ...

    Indian Academy of Sciences (India)

    presently used to control metal temperatures in gas turbine blades. Functionally graded materials ..... In (8) n is the gradient index that controls the average volume fraction of the constituents. Figure 4 shows a ... A FEM code was developed in MATLAB for simulating this heat transfer problem. For code validation in the ...

  5. Analytical method for steady state heat transfer in two-dimensional porous media

    Energy Technology Data Exchange (ETDEWEB)

    Siegal, R.; Goldstein, M.E.

    1970-07-01

    A general technique has been devised for obtaining exact solutions for the heat transfer behavior of a 2- dimensional porous cooled medium. Fluid flows through the porous medium from a reservoir at constant pressure and temperature to a second reservoir at a lower pressure. For the type of flow involved, the surfaces of the porous region that are each at constant pressure are boundaries of constant velocity potential. This fact is used to map the porous region into a strip bounded by parallel potential lines in a complex potential plane. The energy equation, derived by assuming the local matrix and fluid temperatures are equal, is transformed into a separable equation when its independent variables are changed to the coordinates of the potential plane. This allows the general solution for the temperature distribution to be found in the potential plane. The solution is then mapped into the physical plane to yield the heat transfer characteristics of the porous region. An example problem of a porous wall having a step in thickness and a specified surface temperature or heat flux is worked out in detail.

  6. Novel approach to analytical modelling of steady-state heat transfer from the exterior of TEFC induction motors

    Directory of Open Access Journals (Sweden)

    Klimenta Dardan O.

    2017-01-01

    Full Text Available The purpose of this paper is to propose a novel approach to analytical modelling of steady-state heat transfer from the exterior of totally enclosed fan-cooled induction motors. The proposed approach is based on the geometry simplification methods, energy balance equation, modified correlations for forced convection, the Stefan-Boltzmann law, air-flow velocity profiles, and turbulence factor models. To apply modified correlations for forced convection, the motor exterior is presented with surfaces of elementary 3-D shapes as well as the air-flow velocity profiles and turbulence factor models are introduced. The existing correlations for forced convection from a short horizontal cylinder and correlations for heat transfer from straight fins (as well as inter-fin surfaces in axial air-flows are modified by introducing the Prandtl number to the appropriate power. The correlations for forced convection from straight fins and inter-fin surfaces are derived from the existing ones for combined heat transfer (due to forced convection and radiation by using the forced-convection correlations for a single flat plate. Employing the proposed analytical approach, satisfactory agreement is obtained with experimental data from other studies.

  7. Transverse heat transfer coefficient in the dual channel ITER TF CICCs. Part I: Analysis of steady state temperature profiles resulting from annular heating

    Science.gov (United States)

    Lewandowska, Monika; Herzog, Robert

    2011-10-01

    Two ITER TF dual channel Cable-in-Conduit Conductors (CICCs) have been tested in the SULTAN test facility. The samples were heated either by foil heaters mounted on the outside of the conductor jacket or by induced AC losses. The steady-state temperature response of several thermometers installed on the jacket surface as well as inside the cable were analyzed using the two-channel analytical model proposed by Renard et al. to obtain the equivalent transverse heat transfer coefficient between the bundle and central channel as a function of the mass flow rate. In addition, on the basis of the measured pressure drop and helium flow velocities, the friction factors for helium flow in the bundle and in the central channel were determined. The obtained results may serve as a reference for these cables.

  8. Steady-state flow in a rock mass intersected by permeable fracture zones

    International Nuclear Information System (INIS)

    Lindbom, B.

    1986-12-01

    Level 1 of HYDROCOIN consists of seven well-defined test problems. This paper is concerned with Case 2, which is formulated as a generic groundwater flow situation often found in crystalline rock with highly permeable fracture zones in a less permeable rock mass. The case is two-dimensional and modelled with 8-noded, isoparametric, rectangular elements. According to the case definition, calculations of hydraulic head and particle tracking are performed. The computations are carried out with varying degree of discretisation in order to analyse possible impact on the result with respect to nodal density. Further calculations have been performed mainly devoted to mass balance deviations and how these are affected by permeability contrasts, varying degree of spatial discretisation and distortion of finite elements. The distribution of hydraulic head in the domain is less sensitive to differences in nodal density than the trajectories. The hydraulic heads show similar behaviour for three meshes with varying degrees of discretisation. The particle tracking seems to be more sensitive to the level of discretisation. The results obtained with a coarse and medium mesh indicate completely different solutions for one of the pathlines. The coarse mesh is too sparsely discretised for the specified problem. The local mass balance is evaluated for seven runs. The mass balance deviation seems to be considerably more sensitive to the level of discretisation than to both permeability contrasts and deformation of elements. The permeability contrasts between the rock mass and fracture zones vary from a factor of 1000 to 1 (homogeneous properties) with increments of a factor of 10. These calculations in fact give better mass balance with increasing permeability contrasts, contrary to what could be expected. (orig./HP)

  9. Normal right- and left ventricular volumes and myocardial mass in children measured by steady state free precession cardiovascular magnetic resonance

    Directory of Open Access Journals (Sweden)

    Schmitz Achim

    2009-06-01

    Full Text Available Abstract Background Quantification of ventricular volume by Steady State Free Precession (SSFP cardiovascular magnetic resonance is accurate and reproducible. Normal values exist for adults, but are lacking for children. We sought to establish normal values for left and right ventricular volumes, mass and function in healthy children by using SSFP. Methods and results Fifty children (27 females, 23 males without cardiovascular disease were evaluated. Median age was 11 years (range 7 months – 18 years, weight 35 kg (range 7–77 kg, height 146 cm (range 66–181 cm. Thirty-six examinations were performed with breath holding, 14 in freely breathing sedated children. Ventricular volumes and mass were measured in the end systolic and end diastolic phase on SSFP cine images acquired in a short axis plane as a stack of 12 contiguous slices covering full length of both ventricles. Regression analysis showed an exponential relationship between body surface area (BSA and ventricular volumes and mass (normal value = a*BSAb. Normative curves for males and females are presented in relation to BSA for the enddiastolic volume, endsystolic volume and mass of both ventricles. Intra- and interobserver variability of the measurements was within the limits of 2% and 7% respectively, except for right ventricular mass (10%. Conclusion The exponential equation for calculation of normal values for each ventricular parameter and graphical display of normative curves for data acquired in healthy children by SSFP cardiovascular magnetic resonance are provided.

  10. A digital microfluidic system for the investigation of pre-steady-state enzyme kinetics using rapid quenching with MALDI-TOF mass spectrometry

    NARCIS (Netherlands)

    Nichols, K.P.F.; Gardeniers, Johannes G.E.

    2007-01-01

    A digital microfluidic system based on electrowetting has been developed to facilitate the investigation of pre-steady-state reaction kinetics using rapid quenching and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The device consists of individually

  11. Steady State Shift Damage Localization

    DEFF Research Database (Denmark)

    Sekjær, Claus; Bull, Thomas; Markvart, Morten Kusk

    2017-01-01

    The steady state shift damage localization (S3DL) method localizes structural deterioration, manifested as either a mass or stiffness perturbation, by interrogating the damage-induced change in the steady state vibration response with damage patterns cast from a theoretical model. Damage is, thus...... the required accuracy when examining complex structures, an extensive amount of degrees of freedom (DOF) must often be utilized. Since the interrogation matrix for each damage pattern depends on the size of the system matrices constituting the FE-model, the computational time quickly becomes of first...

  12. Molecular structure determination for photogenerated intermediates in photoinduced electron transfer reactions using steady-state and transient XAFS

    Energy Technology Data Exchange (ETDEWEB)

    Chen, L.X.; Wasielewski, M.R.; Rajh, T. [Argonne National Lab., IL (United States). Chemistry Div.

    1996-10-01

    Many photoinduced electron transfer reactions are accompanied by nuclear rearrangements of the molecules involved. In order to understand the reactivities of the molecules and the reaction mechanisms, precise information on the molecular structural changes accompanying the electron transfer is often required. We present here conventional XAFS and transient energy dispersive XAFS studies on structures of excited and photoinduced charge separated state of porphyrin and porphyrin based supermolecules, and structures of TiO{sub 2} colloid and the heavymetal ions that bind to the colloid surfaces during photocatalytic reductions.

  13. Factorised steady states and condensation transitions in ...

    Indian Academy of Sciences (India)

    I will then consider a more general class of mass trans- port models, encompassing continuous mass variables and discrete time updating, and present a necessary and sufficient condition for the steady state to factorise. The prop- erty of factorisation again allows an analysis of the condensation transitions which may occur.

  14. Steady state modeling of desiccant wheels

    DEFF Research Database (Denmark)

    Bellemo, Lorenzo; Elmegaard, Brian; Kærn, Martin Ryhl

    2014-01-01

    systems. A steady state two-dimensional model is formulated and implemented aiming to obtain good accuracy and short computational times. Comparison with experimental data from the literature shows that the model reproduces the physical behavior of desiccant wheels. Mass diffusion in the desiccant should...

  15. Steady states in conformal theories

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    A novel conjecture regarding the steady state behavior of conformal field theories placed between two heat baths will be presented. Some verification of the conjecture will be provided in the context of fluid dynamics and holography.

  16. Body Mass Index and creatinine clearance are associated with steady-state serum concentrations of the cell damage marker S100B in renal transplant recipients

    NARCIS (Netherlands)

    Gross, Sascha; van der Heide, Jaap J. Homan; van Son, Willem J.; Gans, Reinold O. B.; Foell, Dirk; Navis, Gerjan; Bakker, Stephan J. L.

    2010-01-01

    Background: S100B is a prominent cell damage marker which can lead to sustained pro-inflammatory signaling. The aim was to investigate cross-sectional associations of steady-state S100B concentrations, particularly with C-reactive protein (CRP), in renal transplant recipients (RTRs) and also to

  17. Body mass index and creatinine clearance are associated with steady-state serum concentrations of the cell damage marker S100B in renal transplant recipients

    NARCIS (Netherlands)

    Gross, Sascha; Homan van der Heide, Jaap J. J.; van Son, Willem J.; Gans, Reinold O. B.; Foell, Dirk; Navis, Gerjan; Bakker, Stephan J. L.

    2010-01-01

    S100B is a prominent cell damage marker which can lead to sustained pro-inflammatory signaling. The aim was to investigate cross-sectional associations of steady-state S100B concentrations, particularly with C-reactive protein (CRP), in renal transplant recipients (RTRs) and also to investigate

  18. Steady-State Process Modelling

    DEFF Research Database (Denmark)

    Cameron, Ian; Gani, Rafiqul

    2011-01-01

    illustrate the “equation oriented” approach as well as the “sequential modular” approach to solving complex flowsheets for steady state applications. The applications include the Williams-Otto plant, the hydrodealkylation (HDA) of toluene, conversion of ethylene to ethanol and a bio-ethanol process....

  19. Formulation and validation of a two-dimensional steady-state model of desiccant wheels

    DEFF Research Database (Denmark)

    Bellemo, Lorenzo; Elmegaard, Brian; Kærn, Martin R.

    2015-01-01

    systems. A steady-state two-dimensional model is formulated and implemented, aiming to obtain good accuracy and short computational times with the purpose of inclusion in complete system models. The model includes mass and energy balances and correlations for heat and mass transfer based on empirical...... relations from the scientific literature. Convective heat and mass transfer coefficients are computed locally accounting for the entrance length effects. Mass diffusion inside the desiccant material is neglected. Comparison with experimental data from the literature shows that the model reproduces...

  20. Simulation of the steady-state energy transfer in rigid bodies, with convective-radiative boundary conditions, employing a minimum principle

    International Nuclear Information System (INIS)

    Gama, R.M.S. da.

    1992-08-01

    The energy transfer phenomenon in a rigid and opaque body that exchanges energy, with the environment, by convection and by diffuse thermal radiation is studied. The considered phenomenon is described by a partial differential equation, subjected to (nonlinear) boundary conditions. A minimum principle, suitable for a large class of energy transfer problems is presented. Some particular cases are simulated. (author)

  1. Combined Steady-State and Dynamic Heat Exchanger Experiment

    Science.gov (United States)

    Luyben, William L.; Tuzla, Kemal; Bader, Paul N.

    2009-01-01

    This paper describes a heat-transfer experiment that combines steady-state analysis and dynamic control. A process-water stream is circulated through two tube-in-shell heat exchangers in series. In the first, the process water is heated by steam. In the second, it is cooled by cooling water. The equipment is pilot-plant size: heat-transfer areas…

  2. Statistical steady states in turbulent droplet condensation

    Science.gov (United States)

    Bec, Jeremie; Krstulovic, Giorgio; Siewert, Christoph

    2017-11-01

    We investigate the general problem of turbulent condensation. Using direct numerical simulations we show that the fluctuations of the supersaturation field offer different conditions for the growth of droplets which evolve in time due to turbulent transport and mixing. This leads to propose a Lagrangian stochastic model consisting of a set of integro-differential equations for the joint evolution of the squared radius and the supersaturation along droplet trajectories. The model has two parameters fixed by the total amount of water and the thermodynamic properties, as well as the Lagrangian integral timescale of the turbulent supersaturation. The model reproduces very well the droplet size distributions obtained from direct numerical simulations and their time evolution. A noticeable result is that, after a stage where the squared radius simply diffuses, the system converges exponentially fast to a statistical steady state independent of the initial conditions. The main mechanism involved in this convergence is a loss of memory induced by a significant number of droplets undergoing a complete evaporation before growing again. The statistical steady state is characterised by an exponential tail in the droplet mass distribution.

  3. Fundamental Research in Engineering Education. Development of Concept Questions and Inquiry-Based Activities in Thermodynamics and Heat Transfer: An Example for Equilibrium vs. Steady-State

    Science.gov (United States)

    Vigeant, Margot; Prince, Michael; Nottis, Katharyn

    2011-01-01

    This study examines the use of inquiry-based instruction to promote the understanding of critical concepts in thermodynamics and heat transfer. Significant research shows that students frequently enter our courses with tightly held misconceptions about the physical world that are not effectively addressed through traditional instruction. Students'…

  4. Heat and mass transfer

    CERN Document Server

    Baehr, Hans Dieter

    2011-01-01

    This comprehensive textbook provides a solid foundation of knowledge on the principles of heat and mass transfer and shows how to solve problems by applying modern methods. The basic theory is developed systematically, exploring in detail the solution methods to all important problems.   The thoroughly revised 3rd edition includes an introduction to the numerical solution of Finite Elements. A new section on heat and mass transfer in porous media has also been added.   The book will be useful not only to upper-level and graduate students, but also to practicing scientists and engineers, offering a firm understanding of the principles of heat and mass transfer, and showing how to solve problems by applying modern methods. Many completed examples and numerous exercises with solutions facilitate learning and understanding, and an appendix includes data on key properties of important substances.

  5. Diffusion and mass transfer

    CERN Document Server

    Vrentas, James S

    2013-01-01

    The book first covers the five elements necessary to formulate and solve mass transfer problems, that is, conservation laws and field equations, boundary conditions, constitutive equations, parameters in constitutive equations, and mathematical methods that can be used to solve the partial differential equations commonly encountered in mass transfer problems. Jump balances, Green’s function solution methods, and the free-volume theory for the prediction of self-diffusion coefficients for polymer–solvent systems are among the topics covered. The authors then use those elements to analyze a wide variety of mass transfer problems, including bubble dissolution, polymer sorption and desorption, dispersion, impurity migration in plastic containers, and utilization of polymers in drug delivery. The text offers detailed solutions, along with some theoretical aspects, for numerous processes including viscoelastic diffusion, moving boundary problems, diffusion and reaction, membrane transport, wave behavior, sedime...

  6. Mass transfer and transport in salt repositories

    International Nuclear Information System (INIS)

    Pigford, T.H.; Chambre, P.L.; Lee, W.W.L.

    1989-02-01

    Salt is a unique rock isolation of nuclear waste because it is ''dry'' and nearly impermeable. In this paper we summarize some mass-transfer and transport analyses of salt repositories. First we analyses brine migration. Heating by high-level waste can cause brine in grain boundaries to move due to pressure-gradients. We analyze brine migration treating salt as a thermoelastic solid and found that brine migration is transient and localized. We use previously developed techniques to estimate release rates from waste packages by diffusion. Interbeds exist in salt and may be conduits for radionuclide migration. We analyze steady-state migration due to brine flow in the interbed, as a function of the Peclet number. Then we analyze transient mass transfer, both into the interbed and directly to salt, due only to diffusion. Finally we compare mass transfer rates of a waste cylinder in granite facing a fracture and in salt facing an interbed. In all cases, numerical illustrations of the analytic solution are given. 10 refs., 4 figs., 3 tabs

  7. New Tore Supra steady state operating scenario

    International Nuclear Information System (INIS)

    Martin, G.; Parlange, F.; van Houtte, D.; Wijnands, T.

    1995-01-01

    This document deals with plasma control in steady state conditions. A new plasma control systems enabling feedback control of global plasma equilibrium parameters has been developed. It also enables to operate plasma discharge in steady state regime. (TEC). 4 refs., 5 figs

  8. Relationships of body mass index with serum carotenoids, tocopherols and retinol at steady-state and in response to a carotenoid-rich vegetable diet intervention in Filipino schoolchildren.

    Science.gov (United States)

    Ribaya-Mercado, Judy D; Maramag, Cherry C; Tengco, Lorena W; Blumberg, Jeffrey B; Solon, Florentino S

    2008-04-01

    In marginally nourished children, information is scarce regarding the circulating concentrations of carotenoids and tocopherols, and physiological factors influencing their circulating levels. We determined the serum concentrations of carotenoids, tocopherols and retinol at steady state and in response to a 9-week vegetable diet intervention in 9-12-year-old girls (n=54) and boys (n=65) in rural Philippines. We determined cross-sectional relationships of BMI (body mass index) with serum micronutrient levels, and whether BMI is a determinant of serum carotenoid responses to the ingestion of carotenoid-rich vegetables. We measured dietary nutrient intakes and assessed inflammation by measurement of serum C-reactive protein levels. The children had low serum concentrations of carotenoids, tocopherols and retinol as compared with published values for similar-aged children in the U.S.A. The low serum retinol levels can be ascribed to inadequate diets and were not the result of confounding due to inflammation. Significant inverse correlations of BMI and serum all-trans-beta-carotene, 13-cis-beta-carotene, alpha-carotene, lutein, zeaxanthin and alpha-tocopherol (but not beta-cryptoxanthin, lycopene and retinol) were observed among girls at baseline. The dietary intervention markedly enhanced the serum concentrations of all carotenoids. Changes in serum all-trans-beta-carotene and alpha-carotene (but not changes in lutein, zeaxanthin and beta-cryptoxanthin) in response to the dietary intervention were inversely associated with BMI in girls and boys. Thus, in Filipino school-aged children, BMI is inversely related to the steady-state serum concentrations of certain carotenoids and vitamin E, but not vitamin A, and is a determinant of serum beta- and alpha-carotene responses, but not xanthophyll responses, to the ingestion of carotenoid-rich vegetable meals.

  9. Diffusive-dispersive mass transfer in the capillary fringe: Impact of water table fluctuations and heterogeneities

    OpenAIRE

    Grathwohl, Peter; Haberer, Cristina; Ye, Yu; Muniruzzaman, Muhammad; Rolle, Massimo

    2016-01-01

    Diffusive–dispersive mass transfer in the capillary fringe is important for many groundwater quality issues such as transfer of volatile compounds into (and out of) the groundwater, the supply of oxygen for aerobic degradation of hydrocarbons as well as for precipitation of minerals (e.g. iron hydroxides). 2D-laboratory scale experiments were used to investigate the transfer of oxygen into groundwater under non-reactive and reactive conditions, at steady state and with water table fluctuation...

  10. A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on 13C mass isotopologue profiles under non-steady-state conditions

    Directory of Open Access Journals (Sweden)

    Belshoff Alex C

    2011-05-01

    Full Text Available Abstract Background Stable isotope tracing is a powerful technique for following the fate of individual atoms through metabolic pathways. Measuring isotopic enrichment in metabolites provides quantitative insights into the biosynthetic network and enables flux analysis as a function of external perturbations. NMR and mass spectrometry are the techniques of choice for global profiling of stable isotope labeling patterns in cellular metabolites. However, meaningful biochemical interpretation of the labeling data requires both quantitative analysis and complex modeling. Here, we demonstrate a novel approach that involved acquiring and modeling the timecourses of 13C isotopologue data for UDP-N-acetyl-D-glucosamine (UDP-GlcNAc synthesized from [U-13C]-glucose in human prostate cancer LnCaP-LN3 cells. UDP-GlcNAc is an activated building block for protein glycosylation, which is an important regulatory mechanism in the development of many prominent human diseases including cancer and diabetes. Results We utilized a stable isotope resolved metabolomics (SIRM approach to determine the timecourse of 13C incorporation from [U-13C]-glucose into UDP-GlcNAc in LnCaP-LN3 cells. 13C Positional isotopomers and isotopologues of UDP-GlcNAc were determined by high resolution NMR and Fourier transform-ion cyclotron resonance-mass spectrometry. A novel simulated annealing/genetic algorithm, called 'Genetic Algorithm for Isotopologues in Metabolic Systems' (GAIMS was developed to find the optimal solutions to a set of simultaneous equations that represent the isotopologue compositions, which is a mixture of isotopomer species. The best model was selected based on information theory. The output comprises the timecourse of the individual labeled species, which was deconvoluted into labeled metabolic units, namely glucose, ribose, acetyl and uracil. The performance of the algorithm was demonstrated by validating the computed fractional 13C enrichment in these subunits

  11. Heat and mass transfer

    CERN Document Server

    Karwa, Rajendra

    2017-01-01

    This textbook presents the classical treatment of the problems of heat transfer in an exhaustive manner with due emphasis on understanding of the physics of the problems. This emphasis is especially visible in the chapters on convective heat transfer. Emphasis is laid on the solution of steady and unsteady two-dimensional heat conduction problems. Another special feature of the book is a chapter on introduction to design of heat exchangers and their illustrative design problems. A simple and understandable treatment of gaseous radiation has been presented. A special chapter on flat plate solar air heater has been incorporated that covers thermo-hydraulic modeling and simulation. The chapter on mass transfer has been written looking specifically at the needs of the students of mechanical engineering. The book includes a large number and variety of solved problems with supporting line diagrams. The author has avoided duplicating similar problems, while incorporating more application-based examples. All the end-...

  12. Steady State Vapor Bubble in Pool Boiling.

    Science.gov (United States)

    Zou, An; Chanana, Ashish; Agrawal, Amit; Wayner, Peter C; Maroo, Shalabh C

    2016-02-03

    Boiling, a dynamic and multiscale process, has been studied for several decades; however, a comprehensive understanding of the process is still lacking. The bubble ebullition cycle, which occurs over millisecond time-span, makes it extremely challenging to study near-surface interfacial characteristics of a single bubble. Here, we create a steady-state vapor bubble that can remain stable for hours in a pool of sub-cooled water using a femtosecond laser source. The stability of the bubble allows us to measure the contact-angle and perform in-situ imaging of the contact-line region and the microlayer, on hydrophilic and hydrophobic surfaces and in both degassed and regular (with dissolved air) water. The early growth stage of vapor bubble in degassed water shows a completely wetted bubble base with the microlayer, and the bubble does not depart from the surface due to reduced liquid pressure in the microlayer. Using experimental data and numerical simulations, we obtain permissible range of maximum heat transfer coefficient possible in nucleate boiling and the width of the evaporating layer in the contact-line region. This technique of creating and measuring fundamental characteristics of a stable vapor bubble will facilitate rational design of nanostructures for boiling enhancement and advance thermal management in electronics.

  13. The steady state in toroidal traps

    International Nuclear Information System (INIS)

    Goldston, R.

    1997-01-01

    Experiments at the JET, TORE SUPRA, TFTR and DIII-D reactors have corroborated calculations showing that an advanced tokamak configuration with an important self-generated current, a large plasma pressure and thus a large thermonuclear power density, could allow for the construction of fusion steady state reactors with reduced size and cost. Stellarators only need external superconductive coils for reaching the steady state, but it is essential to reduce in a large proportion the plasma self-generated current

  14. Critical issues for steady state operation

    International Nuclear Information System (INIS)

    Ohyabu, Nobuyoshi

    1994-01-01

    Significant progress has been made in the toroidal magnetic fusion research, achieving high quality plasmas which satisfy the breakeven condition. As the next step, such plasmas need to be maintained in a steady state or a longer period. Critical issues for the steady state operation have been discussed briefly, such as high heat load on the divertor plates, deterioration of the energy confinement with increasing power, impurity contamination, including helium (ash), maintaining of the magnetic configuration, erosion of the plasma facing material. (author)

  15. Steady-state magnetohydrodynamic clump turbulence

    International Nuclear Information System (INIS)

    Tetreault, D.J.

    1989-01-01

    The turbulent steady state of the magnetohydrodynamic (MHD) clump instability [Phys. Fluids 31, 2122 (1988)] is investigated. The steady state is determined by the balance between clump growth by turbulent mixing and clump decay by field line stochasticity. The turbulent fields driving the mixing are generated self-consistently from Ampere's law and conserve the magnetic helicity. In the steady state, the mean current and magnetic field satisfy J 0 = μB 0 , where μ depends on the mean-square fluctuation level. Above this critical point (J 0 >μB 0 ), the plasma is MHD clump unstable. MHD clump instability is a dynamical route to the force-free, Taylor state. For the steady state to exist, μ must exceed a threshold on the order of that required for B 0 /sub z/ field reversal. Steady-state MHD clump turbulence corresponds to field reversed Taylor states. From the μ threshold condition, the steady-state fluctuation spectrum (δB/sub rms//B) is calculated and shown to increase with mean driving current as θ 3 , where θ is the pinch parameter

  16. Advanced steady-state operating scenarios

    International Nuclear Information System (INIS)

    Nevins, W.M.; Bulmer, R.H.; Pearlstein, L.D.; Haney, S.W.; Manickam, J.

    1993-01-01

    The goal for advanced steady-state operation in ITER should be to demonstrate the operation of the plasma core for a steady-state fusion reactor. To accomplish this the authors must develop steady-state operating scenarios at high beta for high fusion power density, low auxiliary power requirements (Q CD ≥ 25, where Q CD triple-bond P fusion/P CD and P DC is the power required for sustaining the plasma current) for low recirculating power requirements, and at moderate safety factor (q ψ ≤ 4.5) to minimize the cost for the tokamak core of a steady-state demonstration power reactor based on the operating modes demonstrated in ITER. The key to achieving steady-state operation at high fusion power in ITER will be the development of operating scenarios with very high bootstrap current fractions (f BS ≥ 90%) in which the radial profile of the bootstrap current density is well aligned with that of the total plasma current density, and for which the MHD β-limit exceeds β n * = 0.05 T-m/MA. They are in the process of developing such operating modes for ITER. In section 1 they propose two advanced steady-state operating points; a preliminary operating point that was the basis for the MHD studies reported in section 2, and a second operating point that has been optimized based on the authors studies to date. In section 2 they present calculations indicating that the initial operating point is stable to MHD ballooning and low-n kink modes (with a conducting wall at r = 1.25a) up to β n * ∼ 6 x 10 -2 T - m/MA. In section 3 they present a free-boundary MHD equilibrium, and show that advanced steady-state operating modes are compatible with the ITER poloidal field system and diverter

  17. A steady state theory for processive cellulases

    DEFF Research Database (Denmark)

    Cruys-Bagger, Nicolaj; Olsen, Jens Elmerdahl; Præstgaard, Eigil

    2013-01-01

    remains to be fully developed. In this paper, we suggest a deterministic kinetic model that relies on a processive set of enzyme reactions and a quasi steady-state assumption. It is shown that this approach is practicable in the sense that it leads to mathematically simple expressions for the steady......-state rate, and only requires data from standard assay techniques as experimental input. Specifically, it is shown that the processive reaction rate at steady state may be expressed by a hyperbolic function related to the conventional Michaelis–Menten equation. The main difference is a ‘kinetic processivity......Processive enzymes perform sequential steps of catalysis without dissociating from their polymeric substrate. This mechanism is considered essential for efficient enzymatic hydrolysis of insoluble cellulose (particularly crystalline cellulose), but a theoretical framework for processive kinetics...

  18. Practical steady-state enzyme kinetics.

    Science.gov (United States)

    Lorsch, Jon R

    2014-01-01

    Enzymes are key components of most biological processes. Characterization of enzymes is therefore frequently required during the study of biological systems. Steady-state kinetics provides a simple and rapid means of assessing the substrate specificity of an enzyme. When combined with site-directed mutagenesis (see Site-Directed Mutagenesis), it can be used to probe the roles of particular amino acids in the enzyme in substrate recognition and catalysis. Effects of interaction partners and posttranslational modifications can also be assessed using steady-state kinetics. This overview explains the general principles of steady-state enzyme kinetics experiments in a practical, rather than theoretical, way. Any biochemistry textbook will have a section on the theory of Michaelis-Menten kinetics, including derivations of the relevant equations. No specific enzymatic assay is described here, although a method for monitoring product formation or substrate consumption over time (an assay) is required to perform the experiments described. © 2014 Elsevier Inc. All rights reserved.

  19. Energy repartition in the nonequilibrium steady state

    NARCIS (Netherlands)

    Yan, Peng; Bauer, G.E.; Zhang, Huaiwu

    2017-01-01

    The concept of temperature in nonequilibrium thermodynamics is an outstanding theoretical issue. We propose an energy repartition principle that leads to a spectral (mode-dependent) temperature in steady-state nonequilibrium systems. The general concepts are illustrated by analytic solutions of

  20. Steady-state spheromak reactor studies

    International Nuclear Information System (INIS)

    Krakowski, R.A.; Hagenson, R.L.

    1985-01-01

    After summarizing the essential elements of a gun-sustained spheromak, the potential for a steady-state is explored by means of a comprehensive physics/engineering/costing model. A range of cost-optimized reactor design points is presented, and the sensitivity of cost to key physics, engineering, and operational variables is reported

  1. Steady state statistics of driven diffusions

    Czech Academy of Sciences Publication Activity Database

    Maes, C.; Netočný, Karel; Wynants, B.

    2008-01-01

    Roč. 387, č. 12 (2008), s. 2675-2689 ISSN 0378-4371 R&D Projects: GA ČR GC202/07/J051 Institutional research plan: CEZ:AV0Z10100520 Keywords : nonequilibrium fluctuations * steady state * diffusion Subject RIV: BE - Theoretical Physics Impact factor: 1.441, year: 2008

  2. Factorised steady states and condensation transitions in ...

    Indian Academy of Sciences (India)

    Scotland. E-mail: martin@ph.ed.ac.uk. Abstract. Systems driven out of equilibrium can often exhibit behaviour not seen in systems in thermal equilibrium – for example phase ... weights rather it will be a nonequilibrium steady state. ... particular cases are: if u(m) = m then the dynamics of each particle is independent.

  3. Steady-state spheromak reactor studies. Revision

    International Nuclear Information System (INIS)

    Krakowski, R.A.; Hagenson, R.L.

    1985-01-01

    After summarizing the essential elements of a gun-sustained spheromak, the potential for a steady-state is explored by means of a comprehensive physics/engineering/costing model. A range of cost-optimized reactor design point is presented, and the sensitivity of cost to key physics, engineering, and operational variables is reported

  4. Intermediates, Catalysts, Persistence, and Boundary Steady States

    DEFF Research Database (Denmark)

    Marcondes de Freitas, Michael; Feliu, Elisenda; Wiuf, Carsten

    2017-01-01

    as cascades of a large class of post-translational modification systems (of which the MAPK cascade and the n-site futile cycle are prominent examples). Since one of the aforementioned sufficient conditions for persistence precludes the existence of boundary steady states, our method also provides a graphical...

  5. Steady-State Creep of Asphalt Concrete

    Directory of Open Access Journals (Sweden)

    Alibai Iskakbayev

    2017-02-01

    Full Text Available This paper reports the experimental investigation of the steady-state creep process for fine-grained asphalt concrete at a temperature of 20 ± 2 °С and under stress from 0.055 to 0.311 MPa under direct tension and was found to occur at a constant rate. The experimental results also determined the start, the end point, and the duration of the steady-state creep process. The dependence of these factors, in addition to the steady-state creep rate and viscosity of the asphalt concrete on stress is satisfactorily described by a power function. Furthermore, it showed that stress has a great impact on the specific characteristics of asphalt concrete: stress variation by one order causes their variation by 3–4.5 orders. The described relations are formulated for the steady-state of asphalt concrete in a complex stressed condition. The dependence is determined between stress intensity and strain rate intensity.

  6. The Steady State Distribution of the Master Equation

    OpenAIRE

    Sano, Mitsusada M.

    2008-01-01

    The steady states of the master equation are investigated. We give two expressions for the steady state distribution of the master equation a la the Zubarev-McLennan steady state distribution, i.e., the exact expression and an expression near equilibrium. The latter expression obtained is consistent with recent attempt of constructing steady state theormodynamics.

  7. Steady state compact toroidal plasma production

    Science.gov (United States)

    Turner, William C.

    1986-01-01

    Apparatus and method for maintaining steady state compact toroidal plasmas. A compact toroidal plasma is formed by a magnetized coaxial plasma gun and held in close proximity to the gun electrodes by applied magnetic fields or magnetic fields produced by image currents in conducting walls. Voltage supply means maintains a constant potential across the electrodes producing an increasing magnetic helicity which drives the plasma away from a minimum energy state. The plasma globally relaxes to a new minimum energy state, conserving helicity according to Taylor's relaxation hypothesis, and injecting net helicity into the core of the compact toroidal plasma. Controlling the voltage so as to inject net helicity at a predetermined rate based on dissipative processes maintains or increases the compact toroidal plasma in a time averaged steady state mode.

  8. Simulating ITER steady-state operation scenarios

    International Nuclear Information System (INIS)

    Kim, S.H.; Casper, T.A.; Campbell, D.J.; Snipes, J.A.; Bulmer, R.; LoDestro, L.L.; Meyer, W.H.; Pearlstein, L.D.

    2015-01-01

    Full text of publication follows. ITER steady-state operation aims at demonstrating fully non-inductive plasma operation at a moderate fusion power multiplication factor (Q) of about 5, for long burn durations of up to 3000 s. In this work, this operational capability is studied using an advanced free-boundary transport simulation code, CORSICA [1-3], including relevant physics and engineering constraints. The tokamak discharge modelling capability of the CORSICA code has been improved by integrating realistic source modules for heating and current drive and a parameterized EPED1 pedestal model. The electro-magnetic ITER machine description is computed using the recent design parameters and the latest source configurations are taken into account. This work has been performed to study the feasibility of the ITER steady-state operation. Although the evolution of internal transport barriers (ITBs) are not yet included in this study, a higher energy confinement over the H-mode confinement (H98>1) is assumed by maintaining a reversed safety factor (q) profile during the flat-top phase. This paper presents several ITER steady-state operation scenarios, including a reference 9 MA case, and also suggests a potential approach for achieving fully non-inductive ITER steady-state operation with Q>5. References: [1] Crotinger, J.A. et al, 1997 LLNL Report UCRL-ID-126284; NTIS PB2005-102154; [2] Casper, T.A. et al, 2010 23. Int. Conf. on Fusion Energy (Daejeon, Korea) ITR/P1-19 accepted for publication in Nuclear Fusion; [3] Kim, S.H. et al, 2012 24. Int. Conf. on Fusion Energy (San Diego, USA) ITR/P1-13. (authors)

  9. Steady-State Diffusion of Water through Soft-Contact LensMaterials

    Energy Technology Data Exchange (ETDEWEB)

    Fornasiero, Francesco; Krull, Florian; Radke, Clayton J.; Prausnitz, JohnM.

    2005-01-31

    Water transport through soft contact lenses (SCL) is important for acceptable performance on the human eye. Chemical-potential gradient-driven diffusion rates of water through soft-contact-lens materials are measured with an evaporation-cell technique. Water is evaporated from the bottom surface of a lens membrane by impinging air at controlled flow rate and humidity. The resulting weight loss of a water reservoir covering the top surface of the contact-lens material is recorded as a function of time. New results are reported for a conventional hydrogel material (SofLens{trademark} One Day, hilafilcon A, water content at saturation W{sub 10} = 70 weight %) and a silicone hydrogel material (PureVision{trademark}, balafilcon A, W{sub 10} = 36 %), with and without surface oxygen plasma treatment. Also, previously reported data for a conventional HEMA-SCL (W{sub 10} = 38 %) hydrogel are reexamined and compared with those for SofLens{trademark} One Day and PureVision{trademark} hydrogels. Measured steady-state water fluxes are largest for SofLens{trademark} One Day, followed by PureVision{trademark} and HEMA. In some cases, the measured steady-state water fluxes increase with rising relative air humidity. This increase, due to an apparent mass-transfer resistance at the surface (trapping skinning), is associated with formation of a glassy skin at the air/membrane interface when the relative humidity is below 55-75%. Steady-state water-fluxes are interpreted through an extended Maxwell-Stefan diffusion model for a mixture of species starkly different in size. Thermodynamic nonideality is considered through Flory-Rehner polymer-solution theory. Shrinking/swelling is self-consistently modeled by conservation of the total polymer mass. Fitted Maxwell-Stefan diffusivities increase significantly with water concentration in the contact lens.

  10. The steady-state modeling and optimization of a refrigeration system for high heat flux removal

    International Nuclear Information System (INIS)

    Zhou Rongliang; Zhang Tiejun; Catano, Juan; Wen, John T.; Michna, Gregory J.; Peles, Yoav; Jensen, Michael K.

    2010-01-01

    Steady-state modeling and optimization of a refrigeration system for high heat flux removal, such as electronics cooling, is studied. The refrigeration cycle proposed consists of multiple evaporators, liquid accumulator, compressor, condenser and expansion valves. To obtain more efficient heat transfer and higher critical heat flux (CHF), the evaporators operate with two-phase flow only. This unique operating condition necessitates the inclusion of a liquid accumulator with integrated heater for the safe operation of the compressor. Due to the projected incorporation of microchannels into the system to enhance the heat transfer in heat sinks, the momentum balance equation, rarely seen in previous vapor compression cycle heat exchangers modeling efforts, is utilized in addition to the mass and energy balance equations to capture the expected significant microchannel pressure drop witnessed in previous experimental investigations. Using the steady-state model developed, a parametric study is performed to study the effect of various external inputs on the system performance. The Pareto optimization is applied to find the optimal system operating conditions for given heat loads such that the system coefficient of performance (COP) is optimized while satisfying the CHF and other system operation constraints. Initial validation efforts show the good agreement between the experimental data and model predictions.

  11. Burn cycle requirements comparison of pulsed and steady-state tokamak reactors

    International Nuclear Information System (INIS)

    Brooks, J.N.; Ehst, D.A.

    1983-12-01

    Burn cycle parameters and energy transfer system requirements were analyzed for an 8-m commercial tokamak reactor using four types of cycles: conventional, hybrid, internal transformer, and steady state. Not surprisingly, steady state is the best burn mode if it can be achieved. The hybrid cycle is a promising alternative to the conventional. In contrast, the internal transformer cycle does not appear attractive for the size tokamak in question

  12. Thermodynamic limit of a nonequilibrium steady state: Maxwell-type construction for a bistable biochemical system.

    Science.gov (United States)

    Ge, Hao; Qian, Hong

    2009-10-02

    We show that the thermodynamic limit of a bistable phosphorylation-dephosphorylation cycle has a selection rule for the "more stable" macroscopic steady state. The analysis is akin to the Maxwell construction. Based on the chemical master equation approach, it is shown that, except at a critical point, bistability disappears in the stochastic model when fluctuation is sufficiently low but unneglectable. Onsager's Gaussian fluctuation theory applies to the unique macroscopic steady state. With an initial state in the basin of attraction of the "less stable" steady state, the deterministic dynamics obtained by the law of mass action is a metastable phenomenon. Stability and robustness in cell biology are emergent stochastic concepts.

  13. Enceladus is not in Steady State

    Science.gov (United States)

    Cheunchitra, T.; Stevenson, D. J.

    2016-12-01

    Libration data tell us there is a global ocean. Topography and gravity tell us that there is substantial compensation at degree 2, meaning that the underside of the ice shell must have topography. This topography will decay, typically on a timescale of order a million years (fortuitously similar to thermal diffusion times through the ice shell), by viscous lateral flow of the ice. This could in principle be compensated in steady state by net melting beneath the poles and a compensating net freezing at the equator. In that model, the ice shell beneath the poles is partially melted with water being continuously produced and percolating to the base (or expelled if there are cracks, as at the South Pole). We have modeled this without an a priori assumption about the strength of tidal heating. We find that even if the tidal heating is zero on average around the equator, then the latent heat release from the required freezing can only be accommodated in steady state if the ice shell is 18km. The ice thickness must be even less at the poles in order to satisfy gravity and topography. Moreover, there must then be substantial tidal heating at the poles and it is physically unreasonable to have the volumetric tidal heating at the equator be enormously less than at the North Pole. For example, if the volumetric tidal heating at the equator is on average one quarter of that at the North Pole then marginal consistency with gravity and topography may be possible for a mean ice thickness at the equator of 12km. The global heat flow may exceed 40GW, much higher than the detectable IR excess (the observed south polar tiger stripe heat flow). Recent work (Fuller et al.) admits orbital evolutions with large heat flow at least for a recent part of the orbital history. However, this thin shell steady state model has difficulty reconciling observed gravity and topography as well as the libration data. We conclude that it is unlikely that Enceladus has no net melting or freezing. The ice

  14. Transport processes: Momentum, heat and mass

    International Nuclear Information System (INIS)

    Geankoplis, C.J.

    1983-01-01

    This book discusses basic transport processes including mass transport. Topics covered are as follows: an introduction to engineering principles and units; principles of momentum transfer and overall balances; principles of momentum transfer and applications; principles of steady-state heat transfer; principles of unsteady-state heat transfer; principles of mass transfer; principles of unsteady-state and convective mass transfer

  15. Mass-transfer properties of microbubbles. 1. Experimental studies.

    Science.gov (United States)

    Bredwell, M D; Worden, R M

    1998-01-01

    Synthesis-gas fermentations have typically been gas-to-liquid mass-transfer-limited due to low solubilities of the gaseous substrates. A potential method to enhance mass-transfer rates is to sparge with microbubble dispersions. Mass-transfer coefficients for microbubble dispersions were measured in a bubble column. Oxygen microbubbles were formed in a dilute Tween 20 solution using a spinning disk apparatus. Axial dispersion coefficients measured for the bubble column ranged from 1.5 to 7.2 cm2/s and were essentially independent of flow rate. A laser-diffraction technique was used to determine the interfacial area per unit gas volume, a. The mass-transfer coefficient, KL, was determined by fitting a plug-flow model to the experimental, steady-state, liquid-phase oxygen-concentration profile. The KL values ranged from 2.9 x 10(-5) to 2.2 x 10(-4) m/s. Volumetric mass-transfer coefficients, KLa, for microbubbles with an average initial diameter of 60 microns ranged from 200 to 1800 h-1. Enhancement of mass transfer using microbubbles was demonstrated for a synthesis-gas fermentation. Butyribacterium methylotrophicum was grown in a continuous, stirred-tank reactor using a tangential filter for total cell recycle. The fermentation KLa values were 14 h-1 for conventional gas sparging through a stainless steel frit and 91 h-1 for microbubble sparging. The Power number of the microbubble generator was determined to be 0.036. Using this value, an incremental power-to-volume ratio to produce microbubbles for a B. methylotrophicum fermentation was estimated to be 0.01 kW/m3 of fermentation capacity.

  16. Producing a steady-state population inversion

    International Nuclear Information System (INIS)

    Richards, R.K.; Griffin, D.C.

    1986-03-01

    An observed steady-state transition at 17.5 nm is identified as the 2p 5 3s3p 4 S/sub 3/2/ → 2p 6 3p 2 P/sub 3/2/ transition in Na-like aluminum. The upper level is populated by electron inner shell ionization of metastable Mg-like aluminum. From the emission intensity, the rate coefficient for populating the upper level is calculated to be approximately 5 x 10 -10 ) cm 3 /sec. Since the upper level is quasimetastable with a lifetime 22 times longer than the lower level, it may be possible to produce a population inversion, if a competing process to populate the lower level can be reduced

  17. Magnetic sensor for steady state tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Neyatani, Yuzuru; Mori, Katsuharu; Oguri, Shigeru; Kikuchi, Mitsuru [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment

    1996-06-01

    A new type of magnetic sensor has been developed for the measurement of steady state magnetic fields without DC-drift such as integration circuit. The electromagnetic force induced to the current which leads to the sensor was used for the measurement. For the high frequency component which exceeds higher than the vibration frequency of sensor, pick-up coil was used through the high pass filter. From the results using tokamak discharges, this sensor can measure the magnetic field in the tokamak discharge. During {approx}2 hours measurement, no DC drift was observed. The sensor can respond {approx}10ms of fast change of magnetic field during disruptions. We confirm the extension of measured range to control the current which leads to the sensor. (author).

  18. Bioaccumulation factors and the steady state assumption for cesium isotopes in aquatic foodwebs near nuclear facilities

    International Nuclear Information System (INIS)

    Rowan, D.J.

    2013-01-01

    Steady state approaches, such as transfer coefficients or bioaccumulation factors, are commonly used to model the bioaccumulation of 137 Cs in aquatic foodwebs from routine operations and releases from nuclear generating stations and other nuclear facilities. Routine releases from nuclear generating stations and facilities, however, often consist of pulses as liquid waste is stored, analyzed to ensure regulatory compliance and then released. The effect of repeated pulse releases on the steady state assumption inherent in the bioaccumulation factor approach has not been evaluated. In this study, I examine the steady state assumption for aquatic biota by analyzing data for two cesium isotopes in the same biota, one isotope in steady state (stable 133 Cs) from geologic sources and the other released in pulses ( 137 Cs) from reactor operations. I also compare 137 Cs bioaccumulation factors for similar upstream populations from the same system exposed solely to weapon test 137 Cs, and assumed to be in steady state. The steady state assumption appears to be valid for small organisms at lower trophic levels (zooplankton, rainbow smelt and 0+ yellow perch) but not for older and larger fish at higher trophic levels (walleye). Attempts to account for previous exposure and retention through a biokinetics approach had a similar effect on steady state, upstream and non-steady state, downstream populations of walleye, but were ineffective in explaining the more or less constant deviation between fish with steady state exposures and non-steady state exposures of about 2-fold for all age classes of walleye. These results suggest that for large, piscivorous fish, repeated exposure to short duration, pulse releases leads to much higher 137 Cs BAFs than expected from 133 Cs BAFs for the same fish or 137 Cs BAFs for similar populations in the same system not impacted by reactor releases. These results suggest that the steady state approach should be used with caution in any situation

  19. Bioaccumulation factors and the steady state assumption for cesium isotopes in aquatic foodwebs near nuclear facilities.

    Science.gov (United States)

    Rowan, D J

    2013-07-01

    Steady state approaches, such as transfer coefficients or bioaccumulation factors, are commonly used to model the bioaccumulation of (137)Cs in aquatic foodwebs from routine operations and releases from nuclear generating stations and other nuclear facilities. Routine releases from nuclear generating stations and facilities, however, often consist of pulses as liquid waste is stored, analyzed to ensure regulatory compliance and then released. The effect of repeated pulse releases on the steady state assumption inherent in the bioaccumulation factor approach has not been evaluated. In this study, I examine the steady state assumption for aquatic biota by analyzing data for two cesium isotopes in the same biota, one isotope in steady state (stable (133)Cs) from geologic sources and the other released in pulses ((137)Cs) from reactor operations. I also compare (137)Cs bioaccumulation factors for similar upstream populations from the same system exposed solely to weapon test (137)Cs, and assumed to be in steady state. The steady state assumption appears to be valid for small organisms at lower trophic levels (zooplankton, rainbow smelt and 0+ yellow perch) but not for older and larger fish at higher trophic levels (walleye). Attempts to account for previous exposure and retention through a biokinetics approach had a similar effect on steady state, upstream and non-steady state, downstream populations of walleye, but were ineffective in explaining the more or less constant deviation between fish with steady state exposures and non-steady state exposures of about 2-fold for all age classes of walleye. These results suggest that for large, piscivorous fish, repeated exposure to short duration, pulse releases leads to much higher (137)Cs BAFs than expected from (133)Cs BAFs for the same fish or (137)Cs BAFs for similar populations in the same system not impacted by reactor releases. These results suggest that the steady state approach should be used with caution in any

  20. Radionuclide mass transfer rates from a pinhole in a waste container for an inventory-limited and a constant concentration source

    International Nuclear Information System (INIS)

    LeNeveu, D.M.

    1996-03-01

    Analytical solutions for transient and steady state diffusive mass transfer rates from a pinhole in a waste container are developed for constant concentration and inventory-limited source conditions. Mass transport in three media are considered, inside the pinhole (medium 2), outside the container (medium 3) and inside the container (medium 1). Simple equations are developed for radionuclide mass transfer rates from a pinhole. It is shown that the medium with the largest mass transfer resistance need only be considered to provide a conservative estimate of mass transfer rates. (author) 11 refs., 3 figs

  1. Mass Transfer Method and Apparatus

    DEFF Research Database (Denmark)

    1995-01-01

    .g. polytetrafluoroethylene (PTFE, Teflon $m(3)) membranes, in the form of hollow fibres having gas-containing pores and contacting the second fluid with the inner surface of the membranes. Useful membranes are characterized in that they e.g. have a porosity ($g(e)) of at least 0.50, a mass transfer coefficient of e...

  2. Dissipative dark matter halos: The steady state solution

    Science.gov (United States)

    Foot, R.

    2018-02-01

    Dissipative dark matter, where dark matter particle properties closely resemble familiar baryonic matter, is considered. Mirror dark matter, which arises from an isomorphic hidden sector, is a specific and theoretically constrained scenario. Other possibilities include models with more generic hidden sectors that contain massless dark photons [unbroken U (1 ) gauge interactions]. Such dark matter not only features dissipative cooling processes but also is assumed to have nontrivial heating sourced by ordinary supernovae (facilitated by the kinetic mixing interaction). The dynamics of dissipative dark matter halos around rotationally supported galaxies, influenced by heating as well as cooling processes, can be modeled by fluid equations. For a sufficiently isolated galaxy with a stable star formation rate, the dissipative dark matter halos are expected to evolve to a steady state configuration which is in hydrostatic equilibrium and where heating and cooling rates locally balance. Here, we take into account the major cooling and heating processes, and numerically solve for the steady state solution under the assumptions of spherical symmetry, negligible dark magnetic fields, and that supernova sourced energy is transported to the halo via dark radiation. For the parameters considered, and assumptions made, we were unable to find a physically realistic solution for the constrained case of mirror dark matter halos. Halo cooling generally exceeds heating at realistic halo mass densities. This problem can be rectified in more generic dissipative dark matter models, and we discuss a specific example in some detail.

  3. A Novel Chronic Opioid Monitoring Tool to Assess Prescription Drug Steady State Levels in Oral Fluid.

    Science.gov (United States)

    Shaparin, Naum; Mehta, Neel; Kunkel, Frank; Stripp, Richard; Borg, Damon; Kolb, Elizabeth

    2017-11-01

    Interpretation limitations of urine drug testing and the invasiveness of blood toxicology have motivated the desire for the development of simpler methods to assess biologically active drug levels on an individualized patient basis. Oral fluid is a matrix well-suited for the challenge because collections are based on simple noninvasive procedures and drug concentrations better correlate to blood drug levels as oral fluid is a filtrate of the blood. Well-established pharmacokinetic models were utilized to generate oral fluid steady state concentration ranges to assess the interpretive value of the alternative matrix to monitor steady state plasma oxycodone levels. Paired oral fluid and plasma samples were collected from patients chronically prescribed oxycodone and quantitatively analyzed by liquid chromatography tandem mass spectrometry. Steady state plasma concentration ranges were calculated for each donor and converted to an equivalent range in oral fluid. Measured plasma and oral fluid oxycodone concentrations were compared with respective matrix-matched steady state ranges, using each plasma steady state classification as the control. A high degree of correlation was observed between matrices when classifying donors according to expected steady state oxycodone concentration. Agreement between plasma and oral fluid steady state classifications was observed in 75.6% of paired samples. This study supports novel application of basic pharmacokinetic knowledge to the pain management industry, simplifying and improving individualized drug monitoring and risk assessment through the use of oral fluid drug testing. Many benefits of established therapeutic drug monitoring in plasma can be realized in oral fluid for patients chronically prescribed oxycodone at steady state. © 2017 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  4. Customized Steady-State Constraints for Parameter Estimation in Non-Linear Ordinary Differential Equation Models.

    Science.gov (United States)

    Rosenblatt, Marcus; Timmer, Jens; Kaschek, Daniel

    2016-01-01

    Ordinary differential equation models have become a wide-spread approach to analyze dynamical systems and understand underlying mechanisms. Model parameters are often unknown and have to be estimated from experimental data, e.g., by maximum-likelihood estimation. In particular, models of biological systems contain a large number of parameters. To reduce the dimensionality of the parameter space, steady-state information is incorporated in the parameter estimation process. For non-linear models, analytical steady-state calculation typically leads to higher-order polynomial equations for which no closed-form solutions can be obtained. This can be circumvented by solving the steady-state equations for kinetic parameters, which results in a linear equation system with comparatively simple solutions. At the same time multiplicity of steady-state solutions is avoided, which otherwise is problematic for optimization. When solved for kinetic parameters, however, steady-state constraints tend to become negative for particular model specifications, thus, generating new types of optimization problems. Here, we present an algorithm based on graph theory that derives non-negative, analytical steady-state expressions by stepwise removal of cyclic dependencies between dynamical variables. The algorithm avoids multiple steady-state solutions by construction. We show that our method is applicable to most common classes of biochemical reaction networks containing inhibition terms, mass-action and Hill-type kinetic equations. Comparing the performance of parameter estimation for different analytical and numerical methods of incorporating steady-state information, we show that our approach is especially well-tailored to guarantee a high success rate of optimization.

  5. Diffusive-dispersive mass transfer in the capillary fringe: Impact of water table fluctuations and heterogeneities

    DEFF Research Database (Denmark)

    Grathwohl, Peter; Haberer, Cristina; Ye, Yu

    Diffusive–dispersive mass transfer in the capillary fringe is important for many groundwater quality issues such as transfer of volatile compounds into (and out of) the groundwater, the supply of oxygen for aerobic degradation of hydrocarbons as well as for precipitation of minerals (e.g. iron...... hydroxides). 2D-laboratory scale experiments were used to investigate the transfer of oxygen into groundwater under non-reactive and reactive conditions, at steady state and with water table fluctuations. Results show that transfer of oxygen is limited by transverse dispersion in the capillary fringe...... and the dispersion coefficients are the same as below the water table. Water table fluctuations cause temporarily increased fluxes of oxygen into groundwater during draining conditions and entrapped air after water table rise. High-permeability inclusions in the capillary fringe enhance mass transfer of oxygen...

  6. Steady State Thermal Analyses of SCEPTOR X-57 Wingtip Propulsion

    Science.gov (United States)

    Schnulo, Sydney L.; Chin, Jeffrey C.; Smith, Andrew D.; Dubois, Arthur

    2017-01-01

    Electric aircraft concepts enable advanced propulsion airframe integration approaches that promise increased efficiency as well as reduced emissions and noise. NASA's fully electric Maxwell X-57, developed under the SCEPTOR program, features distributed propulsion across a high aspect ratio wing. There are 14 propulsors in all: 12 high lift motor that are only active during take off and climb, and 2 larger motors positioned on the wingtips that operate over the entire mission. The power electronics involved in the wingtip propulsion are temperature sensitive and therefore require thermal management. This work focuses on the high and low fidelity heat transfer analysis methods performed to ensure that the wingtip motor inverters do not reach their temperature limits. It also explores different geometry configurations involved in the X-57 development and any thermal concerns. All analyses presented are performed at steady state under stressful operating conditions, therefore predicting temperatures which are considered the worst-case scenario to remain conservative.

  7. Triple echo steady-state (TESS) relaxometry.

    Science.gov (United States)

    Heule, Rahel; Ganter, Carl; Bieri, Oliver

    2014-01-01

    Rapid imaging techniques have attracted increased interest for relaxometry, but none are perfect: they are prone to static (B0 ) and transmit (B1 ) field heterogeneities, and commonly biased by T2 /T1 . The purpose of this study is the development of a rapid T1 and T2 relaxometry method that is completely (T2 ) or partly (T1 ) bias-free. A new method is introduced to simultaneously quantify T1 and T2 within one single scan based on a triple echo steady-state (TESS) approach in combination with an iterative golden section search. TESS relaxometry is optimized and evaluated from simulations, in vitro studies, and in vivo experiments. It is found that relaxometry with TESS is not biased by T2 /T1 , insensitive to B0 heterogeneities, and, surprisingly, that TESS-T2 is not affected by B1 field errors. Consequently, excellent correspondence between TESS and reference spin echo data is observed for T2 in vitro at 1.5 T and in vivo at 3 T. TESS offers rapid T1 and T2 quantification within one single scan, and in particular B1 -insensitive T2 estimation. As a result, the new proposed method is of high interest for fast and reliable high-resolution T2 mapping, especially of the musculoskeletal system at high to ultra-high fields. Copyright © 2013 Wiley Periodicals, Inc.

  8. LASER APPLICATIONS AND OTHER TOPICS IN QUANTUM ELECTRONICS: Synthesis of bulk SiO2 : MxOy materials in a steady-state laser plume

    Science.gov (United States)

    Lebedev, V. F.

    1997-01-01

    An analysis was made of the conditions of existence of a two-component steady-state laser plume in atmospheric air. Such a plume is used in single-stage synthesis of bulk molten materials belonging to the SiO2 : MxOy system. Targets of the SiO2 : M type (metal foil and a silica glass rod) and doping elements with boiling points below and above the boiling point of silica glass are discussed. The regimes and efficiency of steady-state transfer of the dopants are considered. The efficiency of transfer of metal oxides during growth of samples with the aid of a cw CO2 laser is reported to be ~0.05, 0.4, and 0.75g min-1 kW-1 when the mass dopant concentration is ~8%, 20%, and 60% for the oxides of Ti, Cu, and Ni, respectively.

  9. Molecular simulation of steady-state evaporation and condensation in the presence of a non-condensable gas

    Science.gov (United States)

    Liang, Zhi; Keblinski, Pawel

    2018-02-01

    Using molecular dynamics simulations, we study evaporation and condensation of fluid Ar in the presence of a non-condensable Ne gas in a nanochannel. The evaporation and condensation are driven by the temperature difference, ΔTL, between the evaporating and condensing liquid surfaces. The steady-state evaporation and condensation fluxes (JMD) are also affected by the Ne concentration, ρNe, and the nanochannel length. We find that across a wide range of ΔTL and ρNe, JMD is in good agreement with the prediction from Stefan's law and from Schrage relationships. Furthermore, for ΔTL less than ˜20% of the absolute average temperature, we find that both steady-state heat and mass fluxes are proportional to ΔTL. This allows us to determine the interfacial resistance to the heat and mass transfer and compare it with the corresponding resistances in the gas phase. In this context, we derive an analytical expression for the effective thermal conductivity of the gas region in the nanochannel and the mass transport interfacial resistance equivalent length, i.e., the length of the nanochannel for which the resistance to the mass flow is the same as the interfacial resistance to the mass flow.

  10. Two stable steady states in the Hodgkin-Huxley axons

    OpenAIRE

    Aihara, K.; Matsumoto, G.

    1983-01-01

    Two stable steady states were found in the numerical solution of the Hodgkin-Huxley equations for the intact squid axon bathed in potassium-rich sea water with an externally applied inward current. Under the conditions the two stable steady-states exist, the Hodgkin-Huxley equations have a complex bifurcation structure including, in addition to the two stable steady-states, a stable limit cycle, two unstable equilibrium points, and one asymptotically stable equilibrium point. It was also conc...

  11. ATC calculation with steady-state security constraints using Benders decomposition

    International Nuclear Information System (INIS)

    Shaaban, M.; Yan, Z.; Ni, Y.; Wu, F.; Li, W.; Liu, H.

    2003-01-01

    Available transfer capability (ATC) is an important indicator of the usable amount of transmission capacity accessible by assorted parties for commercial trading, ATC calculation is nontrivial when steady-state security constraints are included. In hie paper, Benders decomposition method is proposed to partition the AC problem with steady-state security constraints into a base case master problem and a series of subproblems relevant to various contingencies to include their impacts on ATC. The mathematical model is formulated and the two solution schemes are presented. Computer testing on the 4-bus system and IEEE 30-bus system shows the effectiveness of the proposed method and the solution schemes. (Author)

  12. quasi-steady state thermal performances of a solar air heater with ...

    African Journals Online (AJOL)

    2017-01-17

    Jan 17, 2017 ... For low temperature solar heating applications two kind of solar air ... very low heat transfer rate because of small exchange surfaces ... In the study, mean temperatures and thermal performances of the solar air heater are modelled in quasi-steady state and compared to experimental data. Nomenclature.

  13. Two-Dimensional Simulation of Mass Transfer in Unitized Regenerative Fuel Cells under Operation Mode Switching

    Directory of Open Access Journals (Sweden)

    Lulu Wang

    2016-01-01

    Full Text Available A two-dimensional, single-phase, isothermal, multicomponent, transient model is built to investigate the transport phenomena in unitized regenerative fuel cells (URFCs under the condition of switching from the fuel cell (FC mode to the water electrolysis (WE mode. The model is coupled with an electrochemical reaction. The proton exchange membrane (PEM is selected as the solid electrolyte of the URFC. The work is motivated by the need to elucidate the complex mass transfer and electrochemical process under operation mode switching in order to improve the performance of PEM URFC. A set of governing equations, including conservation of mass, momentum, species, and charge, are considered. These equations are solved by the finite element method. The simulation results indicate the distributions of hydrogen, oxygen, water mass fraction, and electrolyte potential response to the transient phenomena via saltation under operation mode switching. The hydrogen mass fraction gradients are smaller than the oxygen mass fraction gradients. The average mass fractions of the reactants (oxygen and hydrogen and product (water exhibit evident differences between each layer in the steady state of the FC mode. By contrast, the average mass fractions of the reactant (water and products (oxygen and hydrogen exhibit only slight differences between each layer in the steady state of the WE mode. Under either the FC mode or the WE mode, the duration of the transient state is only approximately 0.2 s.

  14. Steady-state analysis of activated sludge processes with a settler model including sludge compression.

    Science.gov (United States)

    Diehl, S; Zambrano, J; Carlsson, B

    2016-01-01

    A reduced model of a completely stirred-tank bioreactor coupled to a settling tank with recycle is analyzed in its steady states. In the reactor, the concentrations of one dominant particulate biomass and one soluble substrate component are modelled. While the biomass decay rate is assumed to be constant, growth kinetics can depend on both substrate and biomass concentrations, and optionally model substrate inhibition. Compressive and hindered settling phenomena are included using the Bürger-Diehl settler model, which consists of a partial differential equation. Steady-state solutions of this partial differential equation are obtained from an ordinary differential equation, making steady-state analysis of the entire plant difficult. A key result showing that the ordinary differential equation can be replaced with an approximate algebraic equation simplifies model analysis. This algebraic equation takes the location of the sludge-blanket during normal operation into account, allowing for the limiting flux capacity caused by compressive settling to easily be included in the steady-state mass balance equations for the entire plant system. This novel approach grants the possibility of more realistic solutions than other previously published reduced models, comprised of yet simpler settler assumptions. The steady-state concentrations, solids residence time, and the wastage flow ratio are functions of the recycle ratio. Solutions are shown for various growth kinetics; with different values of biomass decay rate, influent volumetric flow, and substrate concentration. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Determination of the rate of tetraethylammonium ion transfer across the water/1,2-DCE interface with steady-state voltammetry at a nano-ITIES. Theory and experiment

    Czech Academy of Sciences Publication Activity Database

    Silver, Barry Richard; Holub, Karel; Mareček, Vladimír

    2017-01-01

    Roč. 784, JAN 2017 (2017), s. 1-5 ISSN 1572-6657 R&D Projects: GA ČR GA13-04630S Institutional support: RVO:61388955 Keywords : Ion transfer kinetics * ITIES * Tetraethylammonium ion Subject RIV: CG - Electrochemistry OBOR OECD: Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis) Impact factor: 3.012, year: 2016

  16. A constitutive analysis of transient and steady-state elongational viscosities of bidisperse polystyrene blends

    DEFF Research Database (Denmark)

    Wagner, Manfred H.; Rolon-Garrido, Victor H.; Nielsen, Jens Kromann

    2008-01-01

    The transient and steady-state elongational viscosity data of three bidisperse polystyrene blends were investigated recently by Nielsen et al. [J. Rheol. 50, 453-476 (2006)]. The blends contain a monodisperse high molar mass component (M-L= 390 kg/ mol) in a matrix of a monodisperse small molar...... stretching potential of the long-chain component and an increasing steady-state elongational viscosity with increasing strain rate. In addition, in the dilution regime, a transition from affine chain stretch to nonaffine tube squeeze with decreasing strain rate is identified. The dilution regime ends......, and allowing (albeit by use of empirical linear-viscoelastic shift factors to correct the linear-viscoelastic predictions) for a quantitative description of the transient and steady-state elongational viscosities of the bidisperse polystyrene blends....

  17. Measurement of non-steady-state free fatty acid turnover

    International Nuclear Information System (INIS)

    Jensen, M.D.; Heiling, V.; Miles, J.M.

    1990-01-01

    The accuracy of non-steady-state equations for measuring changes in free fatty acid rate of appearance (Ra) is unknown. In the present study, endogenous lipolysis (traced with [ 14 C]-linoleate) was pharmacologically suppressed in six conscious mongrel dogs. A computer-responsive infusion pump was then used to deliver an intravenous oleic acid emulsion in both constant and linear gradient infusion modes. Both non-steady-state equations with various effective volumes of distribution (V) and steady-state equations were used to measure oleate Ra [( 14 C]oleate). Endogenous lipolysis did not change during the experiment. When oleate Ra increased in a linear gradient fashion, only non-steady-state equations with a large (150 ml/kg) V resulted in erroneous values (9% overestimate, P less than 0.05). In contrast, when oleate Ra decreased in a similar fashion, steady-state and standard non-steady-state equations (V = plasma volume = 50 ml/kg) overestimated total oleate Ra (18 and 7%, P less than 0.001 and P less than 0.05, respectively). Overall, non-steady-state equations with an effective V of 90 ml/kg (1.8 x plasma volume) allowed the most accurate estimates of oleate Ra

  18. Parametrization of the feedback Hamiltonian realizing a pure steady state

    International Nuclear Information System (INIS)

    Yamamoto, Naoki

    2005-01-01

    Feedback control is expected to considerably protect quantum states against decoherence caused by interaction between the system and environment. Especially, Markovian feedback scheme developed by Wiseman can modify the properties of decoherence and eventually recover the purity of the steady state of the corresponding master equation. This paper provides a condition for which the modified master equation has a pure steady state. By applying this condition to a two-qubit system, we obtain a complete parametrization of the feedback Hamiltonian such that the steady state becomes a maximally entangled state

  19. Proton transfer reaction - mass spectrometry

    International Nuclear Information System (INIS)

    Cappellin, L.

    2012-01-01

    Proton transfer reaction mass spectrometry (PTR-MS) provides on-line monitoring of volatile organic compounds (VOCs) with a low detection threshold and a fast response time. Commercially available set-ups are usually based on quadrupole analysers but recently new instruments based on time-of-flight (PTR-ToF-MS) analysers have been proposed and commercialized. PTR-MS has been successfully applied to a variety of fields including environmental science, food science and technology, plant physiology and medical science. Many new challenges arise from the newly available PTR-ToF-MS instruments, ranging from mass calibration and absolute VOC concentration determination to data mining and sample classification. This thesis addresses some of these problems in a coherent framework. Moreover, relevant applications in food science and technology are presented. It includes twelve papers published in peer reviewed journals. Some of them address methodological issues regarding PTR-ToF-MS; the others contain applicative studies of PTR-ToF-MS to food science and technology. Among them, there are the first two published applications of PTR-ToF-MS in this field. (author)

  20. Properties of the steady state distribution of electrons in semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Muscato, Orazio; Di Stefano, Vincenza [Catania Univ. degli Studi (Italy). Dipt. di Matematica e Informatica; Wagner, Wolfgang [Weierstrass-Institut fuer Angewandte Analysis und Stochastik (WIAS) im Forschungsverbund Berlin e.V. (Germany)

    2010-07-01

    This paper studies a Boltzmann transport equation with several electronphonon scattering mechanisms, which describes the charge transport in semiconductors. The electric field is coupled to the electron distribution function via Poisson's equation. Both the parabolic and the quasi-parabolic band approximations are considered. The steady state behaviour of the electron distribution function is investigated by a Monte Carlo algorithm. More precisely, several nonlinear functionals of the solution are calculated that quantify the deviation of the steady state from a Maxwellian distribution with respect to the wave-vector. On the one hand, the numerical results illustrate known theoretical statements about the steady state and indicate possible directions for future studies. On the other hand, the nonlinear functionals provide tools that can be used in the framework of Monte Carlo algorithms for detecting regions in which the steady state distribution has a relatively simple structure, thus providing a basis for domain decomposition methods. (orig.)

  1. H-modes under steady-state conditions in JET

    International Nuclear Information System (INIS)

    Campbell, D.J.; Arshad, S.A.; Gondhalekar, A.; Thomas, P.R.

    1994-01-01

    Two H-mode regimes have been identified in JET in which edge localized modes (ELMs) maintain steady-state conditions. In the first regime, strong gas puffing was used in combined (ICRF plus NBI) heating experiments at powers of up to 20 MW. Rapid ELM activity occurred and at moderate powers (∼ 8 MW) steady-state H-modes with durations of up to 18s and energy confinement times of up to 95% of the JET/D-IIID scaling were established. At high toroidal beta (β N ≥ 1.5) H-mode plasmas were also found to exhibit regular ELM behaviour which resulted in steady-state H-modes with confinement enhancement of ∼ 90% of the JET/D-IIID scaling. This paper examines the plasma properties of these regimes and assesses their implications for steady-state H-mode operation in ignited plasmas. (author)

  2. Stabilizing unstable steady states using extended time-delay autosynchronization.

    Science.gov (United States)

    Chang, Austin; Bienfang, Joshua C.; Hall, G. Martin; Gardner, Jeff R.; Gauthier, Daniel J.

    1998-12-01

    We describe a method for stabilizing unstable steady states in nonlinear dynamical systems using a form of extended time-delay autosynchronization. Specifically, stabilization is achieved by applying a feedback signal generated by high-pass-filtering in real time the dynamical state of the system to an accessible system parameter or variables. Our technique is easy to implement, does not require knowledge of the unstable steady state coordinates in phase space, automatically tracks changes in the system parameters, and is more robust to broadband noise than previous schemes. We demonstrate the controller's efficacy by stabilizing unstable steady states in an electronic circuit exhibiting low-dimensional temporal chaos. The simplicity and robustness of the scheme suggests that it is ideally suited for stabilizing unstable steady states in ultra-high-speed systems. (c) 1998 American Institute of Physics.

  3. Quantum thermodynamics of nanoscale steady states far from equilibrium

    Science.gov (United States)

    Taniguchi, Nobuhiko

    2018-04-01

    We develop an exact quantum thermodynamic description for a noninteracting nanoscale steady state that couples strongly with multiple reservoirs. We demonstrate that there exists a steady-state extension of the thermodynamic function that correctly accounts for the multiterminal Landauer-Büttiker formula of quantum transport of charge, energy, or heat via the nonequilibrium thermodynamic relations. Its explicit form is obtained for a single bosonic or fermionic level in the wide-band limit, and corresponding thermodynamic forces (affinities) are identified. Nonlinear generalization of the Onsager reciprocity relations are derived. We suggest that the steady-state thermodynamic function is also capable of characterizing the heat current fluctuations of the critical transport where the thermal fluctuations dominate. Also, the suggested nonequilibrium steady-state thermodynamic relations seemingly persist for a spin-degenerate single level with local interaction.

  4. Mass transfer and transport in a geologic environment

    International Nuclear Information System (INIS)

    Chambre, P.L.; Pigford, T.H.; Lee, W.W.L.

    1985-04-01

    This report is in a continuing series of reports that present analytic solutions for the dissolution and hydrogeologic transport of radionuclides from geologic repositories of nuclear waste. Previous reports have dealt mainly with radionuclide transport in the far-field, away from the effects of the repository. In the present report, the emphasis is on near-field processes, the transfer and transport of radionuclides in the vicinity of the waste packages. The primary tool used in these analyses is mass transfer theory from chemical engineering. The thrust of our work is to develop methods for predicting the performance of geologic repositories. The subjects treated in the present report are: radionuclide transport from a spherical-equivalent waste form through a backfill; analysis of radionuclide transport through a backfill using a non-linear sorption isotherm; radionuclide transport from a prolate spheroid-equivalent waste form with a backfill; radionuclide transport from a spherical-equivalent waste form through a backfill, where the solubility, diffusivity and retardation coefficients are temperature dependent; a coupled near-field, far-field analysis where dissolution and migration rates are temperature dependent; transport of radionuclides from a point source in a three-dimensional flow field; and a general solution for the transport of radioactive chains in geologic media. There are several important results from the numerical evaluations. First, radioactive decay, higher sorption in the rock and the backfill steepens the gradient for mass transfer, and lead to higher dissolution rates. This is contrary to what was expected by some other workers, but is shown clearly in the analytical solutions. Second, the backfill serves to provide sorption sites so that there is a delay in the arrival of radionuclides in the rock, although this effect is not so important for the steady-state transport of long-lived radionuclides

  5. STEADY-STATE RELATIVISTIC STELLAR DYNAMICS AROUND A MASSIVE BLACK HOLE

    International Nuclear Information System (INIS)

    Bar-Or, Ben; Alexander, Tal

    2016-01-01

    A massive black hole (MBH) consumes stars whose orbits evolve into the small phase-space volume of unstable orbits, the “loss cone,” which take them into the MBH, or close enough to interact strongly with it. The resulting phenomena, e.g., tidal heating and disruption, binary capture and hyper-velocity star ejection, gravitational wave (GW) emission by inspiraling compact remnants, or hydrodynamical interactions with an accretion disk, can produce observable signatures and thereby reveal the MBH, affect its mass and spin evolution, test strong gravity, and probe stars and gas near the MBH. These continuous stellar loss and resupply processes shape the central stellar distribution. We investigate relativistic stellar dynamics near the loss cone of a non-spinning MBH in steady state, analytically and by Monte Carlo simulations of the diffusion of the orbital parameters. These take into account Newtonian mass precession due to enclosed stellar mass, in-plane precession due to general relativity, dissipation by GW, uncorrelated two-body relaxation, correlated resonant relaxation (RR), and adiabatic invariance due to secular precession, using a rigorously derived description of correlated post-Newtonian dynamics in the diffusion limit. We argue that general maximal entropy considerations strongly constrain the orbital diffusion in steady state, irrespective of the relaxation mechanism. We identify the exact phase-space separatrix between plunges and inspirals, and predict their steady-state rates. We derive the dependence of the rates on the mass of the MBH, show that the contribution of RR in steady state is small, and discuss special cases where unquenched RR in restricted volumes of phase-space may affect the steady state substantially

  6. Robust Steady State Analysis of the Power Grid

    OpenAIRE

    Pandey, Amritanshu; Jereminov, Marko; Wagner, Martin R.; Bromberg, David M.; Hug, Gabriela; Pileggi, Larry

    2018-01-01

    A robust methodology for obtaining the steady-state solution of the power grid is essential for reliable operation as well as planning of the future transmission and distribution grid. At present, disparate methods exist for steady-state analysis of the transmission (power flow) and distribution power grid (three-phase power flow). All existing alternating current (AC) power flow and three-phase power flow analyses formulate a non-linear problem that generally lacks the ability to ensure conv...

  7. Steady-state leaching of tritiated water from silica gel

    DEFF Research Database (Denmark)

    Das, H.A.; Hou, Xiaolin

    2009-01-01

    Aqueous leaching of tritium from silica gel, loaded by absorption of water vapor, makes part of reactor de-commissioning. It is found to follow the formulation of steady-state diffusion.......Aqueous leaching of tritium from silica gel, loaded by absorption of water vapor, makes part of reactor de-commissioning. It is found to follow the formulation of steady-state diffusion....

  8. Selection of steady states in planar Darcy convection

    International Nuclear Information System (INIS)

    Tsybulin, V.G.; Karasoezen, B.; Ergenc, T.

    2006-01-01

    The planar natural convection of an incompressible fluid in a porous medium is considered. We study the selection of steady states under temperature perturbations on the boundary. A selection map is introduced in order to analyze the selection of a steady state from a continuous family of equilibria which exists under zero boundary conditions. The results of finite-difference modeling for a rectangular enclosure are presented

  9. Steady-State Spectroscopic Analysis of Proton-Dependent Electron Transfer on Pyrazine-Appended Metal Dithiolenes [Ni(pdt)2], [Pd(pdt)2], and [Pt(pdt)2] (pdt = 2,3-Pyrazinedithiol).

    Science.gov (United States)

    Kennedy, Steven R; Kozar, Morgan N; Yennawar, Hemant P; Lear, Benjamin J

    2016-09-06

    We report the structural, electronic, and acid/base properties of a series of ML2 metal dithiolene complexes, where M = Ni, Pd, Pt and L = 2,3-pyrazinedithiol. These complexes are non-innocent and possess strong electronic coupling between ligands across the metal center. The electronic coupling can be readily quantified in the monoanionic mixed valence state using Marcus-Hush theory. Analysis of the intervalence charge transfer (IVCT) band reveals that that electronic coupling in the mixed valence state is 5800, 4500, and 5700 cm(-1) for the Ni, Pd, and Pt complexes, respectively. We then focus on their response to acid titration in the mixed valence state, which generates the asymmetrically protonated mixed valence mixed protonated state. For all three complexes, protonation results in severe attenuation of the electronic coupling, as measured by the IVCT band. We find nearly 5-fold decreases in electronic coupling for both Ni and Pt, while, for the Pd complex, the electronic coupling is reduced to the point that the IVCT band is no longer observable. We ascribe the reduction in electronic coupling to charge pinning induced by asymmetric protonation. The more severe reduction in coupling for the Pd complex is a result of greater energetic mismatch between ligand and metal orbitals, reflected in the smaller electronic coupling for the pure mixed valence state. This work demonstrates that the bridging metal center can be used to tune the electronic coupling in both the mixed valence and mixed valence mixed protonated states, as well as the magnitude of change of the electronic coupling that accompanies changes in protonation state.

  10. HEAT-MASS TRANSFER IN MOVING MELT

    Directory of Open Access Journals (Sweden)

    R. I. Yesman

    2005-01-01

    Full Text Available The paper gives mathematical formation and solution of the heat-mass transfer problem when liquid metals are flowing in the channels of complicated geometry. The problem is solved with the help of numerical methods. A method of control volume is used for finite-difference approximation of transfer equations. The research results can be applied for execution of a numerical experiment while investigating heat-mass transfer in liquid-metal heat-transfer and reological media.

  11. Pre-steady state transients in the Drosophila alcohol dehydrogenase catalyzed reaction: isotope effects and stereospecificity

    International Nuclear Information System (INIS)

    Place, A.R.; Eccleston, J.F.

    1987-01-01

    The alcohol dehydrogenase (ADH) isolated from Drosophila is unique among alcohol metabolizing enzymes by not requiring metals for catalysis, by showing 4-pro-S (B-sided) hydride transfer stereospecificity, and by possessing a greater catalytic turnover rate for secondary alcohols than for primary alcohols. They have extended their studies on the kinetic mechanism for this enzyme by examining the pre-steady state transients of ternary complex interconversion using stopped-flow fluorescence methods. When enzyme and a 30-fold molar excess of NADH is mixed with excess acetadehyde, methyl ethyl ketone (MEK), or cyclohexanone a rapid (> 100 s -1 ) transient is observe before the steady-state. The rates are insensitive to isotope substitution. With the substrate MEK, the rate and amplitude suggests a single turnover of the enzyme. Similar pre-steady state transients are observed when enzyme and a 50-fold molar excess of NAD + is mixed with ethanol, 2-propanol, and cyclohexanol. The rates show a hyperbolic concentration dependence and a deuterium isotope effect. With d 6 -deuteroethanol the transient no longer occurs in the pre-steady state. When the optical isomers of secondary alcohols are used as substrates, transients are observed only in the R-(-) isomers for all chain lengths. With 2-S(+)-heptanol and 2-S(+)-octanol no transients occur

  12. Quasi-steady state aerodynamics of the cheetah tail

    Directory of Open Access Journals (Sweden)

    Amir Patel

    2016-08-01

    Full Text Available During high-speed pursuit of prey, the cheetah (Acinonyx jubatus has been observed to swing its tail while manoeuvring (e.g. turning or braking but the effect of these complex motions is not well understood. This study demonstrates the potential of the cheetah's long, furry tail to impart torques and forces on the body as a result of aerodynamic effects, in addition to the well-known inertial effects. The first-order aerodynamic forces on the tail are quantified through wind tunnel testing and it is observed that the fur nearly doubles the effective frontal area of the tail without much mass penalty. Simple dynamic models provide insight into manoeuvrability via simulation of pitch, roll and yaw tail motion primitives. The inertial and quasi-steady state aerodynamic effects of tail actuation are quantified and compared by calculating the angular impulse imparted onto the cheetah's body and its shown aerodynamic effects contribute to the tail's angular impulse, especially at the highest forward velocities.

  13. Quasi-steady state aerodynamics of the cheetah tail.

    Science.gov (United States)

    Patel, Amir; Boje, Edward; Fisher, Callen; Louis, Leeann; Lane, Emily

    2016-08-15

    During high-speed pursuit of prey, the cheetah (Acinonyx jubatus) has been observed to swing its tail while manoeuvring (e.g. turning or braking) but the effect of these complex motions is not well understood. This study demonstrates the potential of the cheetah's long, furry tail to impart torques and forces on the body as a result of aerodynamic effects, in addition to the well-known inertial effects. The first-order aerodynamic forces on the tail are quantified through wind tunnel testing and it is observed that the fur nearly doubles the effective frontal area of the tail without much mass penalty. Simple dynamic models provide insight into manoeuvrability via simulation of pitch, roll and yaw tail motion primitives. The inertial and quasi-steady state aerodynamic effects of tail actuation are quantified and compared by calculating the angular impulse imparted onto the cheetah's body and its shown aerodynamic effects contribute to the tail's angular impulse, especially at the highest forward velocities. © 2016. Published by The Company of Biologists Ltd.

  14. [On the terminology of auditory steady-state responses. What differentiates steady-state and transient potentials?].

    Science.gov (United States)

    Mühler, R

    2012-05-01

    Recording human auditory steady-state responses (ASSR) at different frequencies allows objective assessment of auditory thresholds. Common practice has been to record ASSR to pure tones that are sinusoidally modulated in amplitude and frequency. Recently, optimized chirp stimuli have been proposed to evoke transient as well as steady-state responses. Because of the resulting uncertainty about the different methods, this paper aims to reconsider the terminology of transient and steady-state responses. Two experiments demonstrate the smooth transition between transient and steady-state responses. In experiment 1, click-evoked auditory brainstem responses (ABR) were recorded over a wide range of stimulus repetition rates (24/s to 72/s). In experiment 2, auditory steady-state responses were recorded for the same stimulus repetition rates, using three different stimulus types: an amplitude modulated 1-kHz tone (AM), a 1-kHz tone-burst (TB) and a flat-spectrum chirp. Experiment 1 demonstrates the merging of the typical ABR wave complexes at higher repetition rates, forming a steady-state response. This effect can only be observed if the time window is extended far beyond the window traditionally used for clinical ABR recordings. Experiment 2 reveals similar ASSR amplitude spectra regardless of the stimulus type and repetition rate used. Steady-state responses can be evoked for a large variety of stimulus types and repetition rates. Thus, from a clinician's point of view, steady-state responses cannot be considered a new type of evoked responses. They differ from transient responses primarily in the frequency response method and the longer timeframe required.

  15. FORMULATION OF NON-STEADY-STATE DUST FORMATION PROCESS IN ASTROPHYSICAL ENVIRONMENTS

    International Nuclear Information System (INIS)

    Nozawa, Takaya; Kozasa, Takashi

    2013-01-01

    The non-steady-state formation of small clusters and the growth of grains accompanied by chemical reactions are formulated under the consideration that the collision of key gas species (key molecule) controls the kinetics of dust formation process. The formula allows us to evaluate the size distribution and condensation efficiency of dust formed in astrophysical environments. We apply the formulation to the formation of C and MgSiO 3 grains in the ejecta of supernovae, as an example, to investigate how the non-steady effect influences the formation process, condensation efficiency f con, ∞ , and average radius a ave, ∞ of newly formed grains in comparison with the results calculated with the steady-state nucleation rate. We show that the steady-state nucleation rate is a good approximation if the collision timescale of key molecule τ coll is much smaller than the timescale τ sat with which the supersaturation ratio increases; otherwise the effect of the non-steady state becomes remarkable, leading to a lower f con, ∞ and a larger a ave, ∞ . Examining the results of calculations, we reveal that the steady-state nucleation rate is applicable if the cooling gas satisfies Λ ≡ τ sat /τ coll ∼> 30 during the formation of dust, and find that f con, ∞ and a ave, ∞ are uniquely determined by Λ on at the onset time t on of dust formation. The approximation formulae for f con, ∞ and a ave, ∞ as a function of Λ on could be useful in estimating the mass and typical size of newly formed grains from observed or model-predicted physical properties not only in supernova ejecta but also in mass-loss winds from evolved stars

  16. The steady state: is it a neglectable or a compulsory condition for determining renal clearance

    International Nuclear Information System (INIS)

    Bongartz, W.; Kuni, H.; Ridder, H.W.; Naber, K.

    1975-01-01

    The first part of the paper reviews critically the whole-body counter technique with falling blood activity level for measuring renal clearance. It is proved that the methodological assumption that the classic clearance formula in its differential mode can be applied is not fulfilled under routine conditions for several reasons. Therefore, that procedure has to be judged as a ''clearance-equivalent'' method. The second part describes the development of a steady-state clearance procedure to a practicable method. By using a subcutaneous (s.c.) autogenous blood depot of 51 Cr-EDTA the authors achieve a quasi constant level of blood activity which is nearly equivalent to that achievable by means of a continuous infusion technique. The third part describes a further development of this method into a ''total clearance'' method by means of a new and quantitative two-compartment analysis. The authors discuss the conditions under which the main criterion of a steady state (input equal to output) is realized and show that (1) the steady state is a condition absolutely necessary for the exact determination of renal clearance, and (2) the standard condition of constant blood level is neither sufficient to prove a steady state nor essential for a mass balance. This conception of determining renal clearance indirectly by means of a complete two-compartment analysis seems to have advantages over competitive procedures. At a reasonable expense of hardware and personnel this method involves minimal discomfort to the patient. (author)

  17. Performance simulation of the JPL solar-powered distiller. Part 1: Quasi-steady-state conditions. [for cooling microwave equipment

    Science.gov (United States)

    Yung, C. S.; Lansing, F. L.

    1983-01-01

    A 37.85 cu m (10,000 gallons) per year (nominal) passive solar powered water distillation system was installed and is operational in the Venus Deep Space Station. The system replaced an old, electrically powered water distiller. The distilled water produced with its high electrical resistivity is used to cool the sensitive microwave equipment. A detailed thermal model was developed to simulate the performance of the distiller and study its sensitivity under varying environment and load conditions. The quasi-steady state portion of the model is presented together with the formulas for heat and mass transfer coefficients used. Initial results indicated that a daily water evaporation efficiency of 30% can be achieved. A comparison made between a full day performance simulation and the actual field measurements gave good agreement between theory and experiment, which verified the model.

  18. Theoretical research of helium pulsating heat pipe under steady state conditions

    International Nuclear Information System (INIS)

    Xu, D; Liu, H M; Li, L F; Huang, R J; Wang, W

    2015-01-01

    As a new-type heat pipe, pulsating heat pipe (PHP) has several outstanding features, such as great heat transport ability, strong adjustability, small size and simple construction. PHP is a complex two-phase flow system associated with many physical subjects and parameters, which utilizes the pressure and temperature changes in volume expansion and contraction during phase changes to excite the pulsation motion of liquid plugs and vapor bubbles in the capillary tube between the evaporator and the condenser. At present time, some experimental investigation of helium PHP have been done. However, theoretical research of helium PHP is rare. In this paper, the physical and mathematical models of operating mechanism for helium PHP under steady state are established based on the conservation of mass, momentum, and energy. Several important parameters are correlated and solved, including the liquid filling ratio, flow velocity, heat power, temperature, etc. Based on the results, the operational driving force and flow resistances of helium PHP are analysed, and the flow and heat transfer is further studied. (paper)

  19. Steady State Analysis of Multiple Effect Evaporation (MEE) Desalination Process

    International Nuclear Information System (INIS)

    Ahmad, S.

    2012-01-01

    Life without water is not possible. Like other natural resources, the global resources of fresh water are unevenly distributed. The world population is increasing at very rapid rate while the natural water resources remain constant. This gap is expected to widen dramatically in the near future. Our country like most countries in the east suffer from water stressed condition. Desalination is only the logical or available solution. In MED units, the feed seawater sprayed individually in each effect is heated to form pure vapors, which condense to form product water. Irrespective of the continuous development of the desalination industry the thermal desalination is still expensive. The study presented in this thesis is motivated by, to study the impact of various cost controlling parameters on the performance of MEE desalination process. KANUPP has two desalination plants (RO and NDDP). The NDDP has parallel feed cross flow multiple effect evaporation (MEE-PC) configurations. The study presented in this thesis describes a simplified steady state mathematical model to analyze the MED systems. The results obtained by the model are compared with the NDDP data. The developed model is used to investigate the effect of the parameters controlling the product water cost. These parameters includes thermal performance ratio, cooling water flow rate and heat transfer area. It can also be used to study the effect of variation in the operating conditions of the plant on the plant performance. The effect of the process variables on the performance of MED is carried out. This includes the effect of number of effects, intake seawater salinity and heating stream temperature, vacuum condition in term of vapor temperature of last effect. (author)

  20. A steady state solution to a field reversed configuration

    International Nuclear Information System (INIS)

    Okamoto, M.

    1987-01-01

    To find a steady state field reversed configuration, a method is considered for sustaining the diamagnetic plasma current by a seed current externally driven at the field null point. The steady state solution is obtained by solving the one-dimensional fluid equations including equilibrium and transport. It is found that the amount of seed current necessary to maintain a steady field reversal depends strongly on τ B /τ N , where τ B and τ N are the magnetic diffusion times and the particle confinement time, respectively. As τ B /τ N increases, more flux is excluded from the plasma. The steady state solution is applied to a D-T ignited plasma. (author)

  1. From Steady-State To Cyclic Metal Forming Processes

    International Nuclear Information System (INIS)

    Montmitonnet, Pierre

    2007-01-01

    Continuous processes often exhibit a high proportion of steady state, and have been modeled with steady-state formulations for thirty years, resulting in very CPU-time efficient computations. On the other hand, incremental forming processes generally remain a challenge for FEM software, because of the local nature of deformation compared with the size of the part to be formed, and of the large number of deformation steps needed. Among them however, certain semi-continuous metal forming processes can be characterized as periodic, or cyclic. In this case, an efficient computational strategy can be derived from the ideas behind the steady-state models. This will be illustrated with the example of pilgering, a seamless tube cold rolling process

  2. Structural simplification of chemical reaction networks in partial steady states.

    Science.gov (United States)

    Madelaine, Guillaume; Lhoussaine, Cédric; Niehren, Joachim; Tonello, Elisa

    2016-11-01

    We study the structural simplification of chemical reaction networks with partial steady state semantics assuming that the concentrations of some but not all species are constant. We present a simplification rule that can eliminate intermediate species that are in partial steady state, while preserving the dynamics of all other species. Our simplification rule can be applied to general reaction networks with some but few restrictions on the possible kinetic laws. We can also simplify reaction networks subject to conservation laws. We prove that our simplification rule is correct when applied to a module of a reaction network, as long as the partial steady state is assumed with respect to the complete network. Michaelis-Menten's simplification rule for enzymatic reactions falls out as a special case. We have implemented an algorithm that applies our simplification rules repeatedly and applied it to reaction networks from systems biology. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  3. Contour analysis of steady state tokamak reactor performance

    International Nuclear Information System (INIS)

    Devoto, R.S.; Fenstermacher, M.E.

    1990-01-01

    A new method of analysis for presenting the possible operating space for steady state, non-ignited tokamak reactors is proposed. The method uses contours of reactor performance and plasma characteristics, fusion power gain, wall neutron flux, current drive power, etc., plotted on a two-dimensional grid, the axes of which are the plasma current I p and the normalized beta, β n = β/(I p /aB 0 ), to show possible operating points. These steady state operating contour plots are called SOPCONS. This technique is illustrated in an application to a design for the International Thermonuclear Experimental Reactor (ITER) with neutral beam, lower hybrid and bootstrap current drive. The utility of the SOPCON plots for pointing out some of the non-intuitive considerations in steady state reactor design is shown. (author). Letter-to-the-editor. 16 refs, 3 figs, 1 tab

  4. Steady-state analysis of the nickel oxide in neutral and weakly alkaline solutions

    International Nuclear Information System (INIS)

    Albu, C.; Deconinck, D.; Hotoiu, L.; Deconinck, J.; Topa, V.

    2013-01-01

    Thin passive nickel oxides are investigated in neutral and weakly alkaline pH solutions under steady-state conditions. The chemical species considered in the oxide film are nickel interstitials and vacancies, as well as oxygen vacancies. The set of differential equations used in this study is solved using the finite element method (FEM) and is able to reproduce the experimental data present in the literature. Steady-state oxide thickness variation with the applied electrode potential presents a linear behavior with an average slope of 2 nm/V. The role of dominant species in these thin films is investigated in terms of current density produced by the reactions at the interfaces, the reactions involving production and consumption of Ni 2+ vacancies playing a major role in the steady-state properties of the oxide. We show that the mass transport of species in the oxide is influenced more by the migration component of the flux than the diffusion component. Our results also show that the flux of Ni 2+ vacancies is approximately two orders of magnitude higher than the flux of oxygen vacancies and Ni 2+ interstitials, making them the dominant defects in the oxide (thus the p-type electronic character is present). Also, the Ni 2+ vacancies were found to have density levels of 10 20 –10 21 cm −3 close to the metal–film interface. Variations of the steady-state thickness and logarithm of the current density with the electrolyte pH, show a linear increase and decrease respectively. Some of these results are compared with data from experiments and simulations done on the iron oxide, showing that Ni forms steady-state passive films that are thinner than the ones formed on Fe under the same environment conditions (pH, temperature, and applied potential)

  5. Factor Xa inhibition by rivaroxaban in the trough steady state can significantly reduce thrombin generation.

    Science.gov (United States)

    Horinaka, Shigeo; Sugawara, Rie; Yonezawa, Yutaka; Ishimitsu, Toshihiko

    2018-01-01

    The aim of the present study was to demonstrate evidence of reduced thrombin generation at the trough plasma rivaroxaban concentration. A single-centre, prospective, nonrandomized, drug-intervention, self-controlled study was conducted in 51 anticoagulation therapy-naïve patients with nonvalvular atrial fibrillation. Plasma rivaroxaban concentration was measured by liquid chromatography tandem mass spectrometry (LC-MS/MS) and the anti-factor Xa chromogenic assay. Partial thrombin time (PT), protein C activity, and protein S antigen, prothrombin fragment 1 + 2 (F1 + 2), D-dimer, thrombomodulin (TM), thrombin-antithrombin complex (TAT), plasminogen activator inhibitor-1 (PAI-1) and tissue factor pathway inhibitor (TFPI) levels were also measured at the trough steady state after 4 weeks of rivaroxaban treatment and compared with baseline. Plasma concentrations obtained by the LC-MS/MS and anti-Xa assays were correlated (r = 0.841, P steady state was 23.6 ng ml -1 , at which F1 + 2, TAT and D-dimer had decreased from the baseline values (P steady state in the first to third quartile groups (+0.79 pg ml -1 , P = 0.048). By contrast, PAI-1, protein C activity, protein S antigen and TM remained within the normal range at the trough steady state. Residual plasma rivaroxaban at the trough steady state may explain the antithrombin effect of rivaroxaban in patients with nonvalvular atrial fibrillation. © 2017 The Authors. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.

  6. Intracellular CHO Cell Metabolite Profiling Reveals Steady-State Dependent Metabolic Fingerprints in Perfusion Culture.

    Science.gov (United States)

    Karst, Daniel J; Steinhoff, Robert F; Kopp, Marie R G; Serra, Elisa; Soos, Miroslav; Zenobi, Renato; Morbidelli, Massimo

    2017-07-01

    Perfusion cell culture processes allow the steady-state culture of mammalian cells at high viable cell density, which is beneficial for overall product yields and homogeneity of product quality in the manufacturing of therapeutic proteins. In this study, the extent of metabolic steady state and the change of the metabolite profile between different steady states of an industrial Chinese hamster ovary (CHO) cell line producing a monoclonal antibody (mAb) was investigated in stirred tank perfusion bioreactors. Matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) of daily cell extracts revealed more than a hundred peaks, among which 76 metabolites were identified by tandem MS (MS/MS) and high resolution Fourier transform ion cyclotron resonance (FT-ICR) MS. Nucleotide ratios (Uridine (U)-ratio, nucleotide triphosphate (NTP)-ratio and energy charge (EC)) and multivariate analysis of all features indicated a consistent metabolite profile for a stable culture performed at 40 × 10 6 cells/mL over 26 days of culture. Conversely, the reactor was operated continuously so as to reach three distinct steady states one after the other at 20, 60, and 40 × 10 6 cells/mL. In each case, a stable metabolite profile was achieved after an initial transient phase of approximately three days at constant cell density when varying between these set points. Clear clustering according to cell density was observed by principal component analysis, indicating steady-state dependent metabolite profiles. In particular, varying levels of nucleotides, nucleotide sugar, and lipid precursors explained most of the variance between the different cell density set points. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 33:879-890, 2017. © 2016 American Institute of Chemical Engineers.

  7. Steady-state pharmacokinetics and metabolism of voriconazole in patients.

    Science.gov (United States)

    Geist, Marcus J P; Egerer, Gerlinde; Burhenne, Jürgen; Riedel, Klaus-Dieter; Weiss, Johanna; Mikus, Gerd

    2013-11-01

    Voriconazole exhibits non-linear pharmacokinetics in adults and is said to be mainly metabolized by CYP2C19 and CYP3A4 to voriconazole-N-oxide. The aim of this study was to obtain data on steady-state pharmacokinetics after dosing for at least 14 days in patients taking additional medication and in vivo data on metabolites other than voriconazole-N-oxide. Thirty-one patients receiving voriconazole as regular therapeutic drug treatment during hospitalization participated in this prospective study. Pharmacokinetic profiles were obtained for the 12 h (dosing interval) after the first orally administered dose (400 mg) or (if possible and) after an orally administered maintenance dose (200 mg) following intake for at least 14 days (n = 14 after first dose; n = 23 after maintenance dose). Blood and urine samples were collected and the concentrations of voriconazole and three of its metabolites (the N-oxide, hydroxy-voriconazole and dihydroxy-voriconazole) were determined, as well as the CYP2C19 genotype of the patients. All other drugs taken by the participating patients were evaluated. A high variability of exposure (AUC) after the first dose was slightly reduced during steady-state dosing for voriconazole (82% to 71%) and the N-oxide (86% to 56%), remained high for hydroxy-voriconazole (79%) and even increased for dihydroxy-voriconazole (97% to 127%). In 16 of the 22 steady-state patients, trough plasma concentrations were steady state stayed almost constant. Hydroxylations of voriconazole seem to be quantitatively more important in its metabolism than N-oxidation. High variability in voriconazole exposure, as well as low steady-state trough plasma concentrations, suggest that the suggested steady-state dosage of 200 mg twice a day has to be increased to prevent disease progression. Therapeutic drug monitoring is probably necessary to optimize the voriconazole dose for individual patients.

  8. Multiple dual mode counter-current chromatography with periodic sample injection: Steady-state and non-steady-state operation.

    Science.gov (United States)

    Kostanyan, Artak E

    2014-12-19

    The multiple dual mode (MDM) counter-current chromatography (CCC) separation consists of a succession of two isocratic counter-current steps and is carried out in series alternating between normal phase and reversed phase operation. The performance of the MDM technique can be improved by the sample re-injection between each of the dual-mode steps. The objective of this work was to develop analytical expressions to describe the MDM CCC with periodic sample injection, which can be used to simulate these processes and select optimal operating conditions for the separation of a given feed mixture. Two possible methods of the MDM separation with periodic sample injection are considered: 1 - steady-state separation: the duration of the flow periods of the phases is kept constant for all the cycles and the steady-state regime is achieved after a certain number of cycles. 2 - non-steady-state separation with variable duration of phase elution steps. It is shown that proper selection of the duration of phase flow times allows to reach complete separation of solutes in continuous steady-state operation mode even in a low efficiency column. This mode of operation provides both high productivity and high resolution. The non-steady-state method with variable duration of phase elution steps offers several options to split a mixture into groups of compounds and/or concentrate target compounds. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Non-equilibrium steady state in the hydro regime

    Energy Technology Data Exchange (ETDEWEB)

    Pourhasan, Razieh [Science Institute, University of Iceland,Dunhaga 5, 107 Reykjavik (Iceland)

    2016-02-01

    We study the existence and properties of the non-equilibrium steady state which arises by putting two copies of systems at different temperatures into a thermal contact. We solve the problem for the relativistic systems that are described by the energy-momentum of a perfect hydro with general equation of state (EOS). In particular, we examine several simple examples: a hydro with a linear EOS, a holographic CFT perturbed by a relevant operator and a barotropic fluid, i.e., P=P(E). Our studies suggest that the formation of steady state is a universal result of the hydro regime regardless of the kind of fluid.

  10. Emergence of advance waves in a steady-state universe

    Energy Technology Data Exchange (ETDEWEB)

    Hobart, R.H.

    1979-10-01

    In standard Wheeler-Feynman electrodynamics advanced waves from any source are absolutely canceled by the advanced waves from the absorber responding to that source. The present work shows this cancellation fails over cosmic distances in a steady-state universe. A test of the view proposed earlier, in a paper which assumed failure of cancellation ad hoc, that zero-point fluctuations of the electromagnetic field are such emergent advanced waves, is posed. The view entails anomalous slowing of spontaneous transition rates at longer emission wavelengths; available data go against this, furnishing additional argument against the suspect assumption that the universe is steady-state.

  11. Emergence of advance waves in a steady-state universe

    International Nuclear Information System (INIS)

    Hobart, R.H.

    1979-01-01

    In standard Wheeler-Feynman electrodynamics advanced waves from any source are absolutely canceled by the advanced waves from the absorber responding to that source. The present work shows this cancellation fails over cosmic distances in a steady-state universe. A test of the view proposed earlier, in a paper which assumed failure of cancellation ad hoc, that zero-point fluctuations of the electromagnetic field are such emergent advanced waves, is posed. The view entails anomalous slowing of spontaneous transition rates at longer emission wavelengths; available data go against this, furnishing additional argument against the suspect assumption that the universe is steady-state

  12. Heat and mass transfer in particulate suspensions

    CERN Document Server

    Michaelides, Efstathios E (Stathis)

    2013-01-01

    Heat and Mass Transfer in Particulate Suspensions is a critical review of the subject of heat and mass transfer related to particulate Suspensions, which include both fluid-particles and fluid-droplet Suspensions. Fundamentals, recent advances and industrial applications are examined. The subject of particulate heat and mass transfer is currently driven by two significant applications: energy transformations –primarily combustion – and heat transfer equipment. The first includes particle and droplet combustion processes in engineering Suspensions as diverse as the Fluidized Bed Reactors (FBR’s) and Internal Combustion Engines (ICE’s). On the heat transfer side, cooling with nanofluids, which include nanoparticles, has attracted a great deal of attention in the last decade both from the fundamental and the applied side and has produced several scientific publications. A monograph that combines the fundamentals of heat transfer with particulates as well as the modern applications of the subject would be...

  13. Numerical study on thermal energy storage performance of phase change material under non-steady-state inlet boundary

    International Nuclear Information System (INIS)

    Tao, Y.B.; He, Y.L.

    2011-01-01

    Highlights: → Based on the unstable solar radiation, a model was established for phase change process under unsteady boundary. → The PCM melting time decreases with the initial inlet temperature increase under the same average inlet temperature. → The melting time reduces about 51.9% with the initial inlet temperature increase from 30 o C to 90 o C. → The melting time decreases with the initial inlet mass flow rate increase under the same average inlet mass flow rate. → The melting time reduces about 36.5% with the initial inlet mass flow rate increase from 2.0 x 10 -4 kg/s to 8.0 x 10 -4 kg/s. -- Abstract: Due to the solar radiation intensity variation over time, the outlet temperature or mass flow rate of heat transfer fluid (HTF) presents non-steady-state characteristics for solar collector. So, in the phase change thermal energy storage (PCTES) unit which is connected to solar collector, the phase change process occurs under the non-steady-state inlet boundary condition. In present paper, regarding the non-steady-state boundary, based on enthalpy method, a two dimensional physical and mathematical model for a shell-and-tube PCTES unit was established and the simulation code was self-developed. The effects of the non-steady-state inlet condition of HTF on the thermal performance of the PCTES unit were numerically analyzed. The results show that when the average HTF inlet temperature in an hour is fixed at a constant value, the melting time (time required for PCM completely melting) decreases with the increase of initial inlet temperature. When the initial inlet temperature increases from 30 o C to 90 o C, the melting time will decrease from 42.75 min to 20.58 min. However, the total TES capacity in an hour reduces from 338.9 kJ/kg to 211.5 kJ/kg. When the average inlet mass flow rate in an hour is fixed at a constant value, with the initial HTF inlet mass flow rate increasing, the melting time of PCM decreases. The initial inlet mass flow rate

  14. Methods of computing steady-state voltage stability margins of power systems

    Energy Technology Data Exchange (ETDEWEB)

    Chow, Joe Hong; Ghiocel, Scott Gordon

    2018-03-20

    In steady-state voltage stability analysis, as load increases toward a maximum, conventional Newton-Raphson power flow Jacobian matrix becomes increasingly ill-conditioned so power flow fails to converge before reaching maximum loading. A method to directly eliminate this singularity reformulates the power flow problem by introducing an AQ bus with specified bus angle and reactive power consumption of a load bus. For steady-state voltage stability analysis, the angle separation between the swing bus and AQ bus can be varied to control power transfer to the load, rather than specifying the load power itself. For an AQ bus, the power flow formulation is only made up of a reactive power equation, thus reducing the size of the Jacobian matrix by one. This reduced Jacobian matrix is nonsingular at the critical voltage point, eliminating a major difficulty in voltage stability analysis for power system operations.

  15. Steady-state, pre-steady-state, and single-turnover kinetic measurement for DNA glycosylase activity.

    Science.gov (United States)

    Sassa, Akira; Beard, William A; Shock, David D; Wilson, Samuel H

    2013-08-19

    Human 8-oxoguanine DNA glycosylase (OGG1) excises the mutagenic oxidative DNA lesion 8-oxo-7,8-dihydroguanine (8-oxoG) from DNA. Kinetic characterization of OGG1 is undertaken to measure the rates of 8-oxoG excision and product release. When the OGG1 concentration is lower than substrate DNA, time courses of product formation are biphasic; a rapid exponential phase (i.e. burst) of product formation is followed by a linear steady-state phase. The initial burst of product formation corresponds to the concentration of enzyme properly engaged on the substrate, and the burst amplitude depends on the concentration of enzyme. The first-order rate constant of the burst corresponds to the intrinsic rate of 8-oxoG excision and the slower steady-state rate measures the rate of product release (product DNA dissociation rate constant, k(off)). Here, we describe steady-state, pre-steady-state, and single-turnover approaches to isolate and measure specific steps during OGG1 catalytic cycling. A fluorescent labeled lesion-containing oligonucleotide and purified OGG1 are used to facilitate precise kinetic measurements. Since low enzyme concentrations are used to make steady-state measurements, manual mixing of reagents and quenching of the reaction can be performed to ascertain the steady-state rate (k(off)). Additionally, extrapolation of the steady-state rate to a point on the ordinate at zero time indicates that a burst of product formation occurred during the first turnover (i.e. y-intercept is positive). The first-order rate constant of the exponential burst phase can be measured using a rapid mixing and quenching technique that examines the amount of product formed at short time intervals (steady-state phase and corresponds to the rate of 8-oxoG excision (i.e. chemistry). The chemical step can also be measured using a single-turnover approach where catalytic cycling is prevented by saturating substrate DNA with enzyme (E>S). These approaches can measure elementary rate

  16. Canonical structure of dynamical fluctuations in mesoscopic nonequilibrium steady states

    Czech Academy of Sciences Publication Activity Database

    Maes, C.; Netočný, Karel

    2008-01-01

    Roč. 82, č. 3 (2008), 30003/1-30003/6 ISSN 0295-5075 R&D Projects: GA ČR GC202/07/J051 Institutional research plan: CEZ:AV0Z10100520 Keywords : nonequilibrium fluctuations * steady state * Onsager- Machlup theory Subject RIV: BE - Theoretical Physics Impact factor: 2.203, year: 2008

  17. Application of Monte Carlo Method to Steady State Heat Conduction ...

    African Journals Online (AJOL)

    The Monte Carlo method was used in modelling steady state heat conduction problems. The method uses the fixed and the floating random walks to determine temperature in the domain of the definition of the heat conduction equation, at a single point directly. A heat conduction problem with an irregular shaped geometry ...

  18. Steady-state equations of even flux and scattering

    International Nuclear Information System (INIS)

    Verwaerde, D.

    1985-11-01

    Some mathematical properties of steady-state equation of even flux are shown in variational formalism. This theoretical frame allows to study the existence of a solution and its asymptotical behavior in opaque media (i.e. the relation with scattering equation). At last it allows to qualify the convergence velocity of resolution iterative processes used practically [fr

  19. Principle of Entropy Maximization for Nonequilibrium Steady States

    DEFF Research Database (Denmark)

    Shapiro, Alexander; Stenby, Erling Halfdan

    2002-01-01

    The goal of this contribution is to find out to what extent the principle of entropy maximization, which serves as a basis for the equilibrium thermodynamics, may be generalized onto non-equilibrium steady states. We prove a theorem that, in the system of thermodynamic coordinates, where entropy...

  20. Steady-state response of a micropolar generalized thermoelastic ...

    Indian Academy of Sciences (India)

    The linear theory of micropolar thermoelasticity was developed by extending the theory of micropolar continua to include thermal effects by Eringen [2] and Nowacki. [13]. Steady state response to moving loads in elasticity have been discussed in Fung [7]. Different authors [1,9,10,11,14,16±18] discussed different problems ...

  1. Herd-Level Modeling and Steady-State Livestock Productivity ...

    African Journals Online (AJOL)

    ... an outline of the scope for applications and addresses the prospects for refinement and model extensions. The algorithms for use in development of steady state derivations include transition of matrices in a Markov Chain approach, continuous differential equations and actuarial approach built on life and fecundity tables.

  2. Correlates of Steady-State Haematocrit and Hepatosplenomegaly in ...

    African Journals Online (AJOL)

    Backgroup: Sickle cell disease is a common genetic disorder in Nigeria. Objectives: To determine the steady state haematocrit, liver size and spleen size in children with sickle cell disease and the factors that influence them. Methods: This was a retrospective study of children with sickle cell disorders who attended the ...

  3. Plasticity, Fracture and Friction in Steady-State Plate Cutting

    DEFF Research Database (Denmark)

    Simonsen, Bo Cerup; Wierzbicki, Tomasz

    1997-01-01

    A closed form solution to the problem of steady-state wedge cutting through a ductile metal plate is presented. The considered problem is an idealization of a ship bottom raking process, i.e. a continuous cutting damage of a ship bottom by a hard knife-like rock in a grounding event. A new...

  4. Classical Orbital Paramagnetism in Non-equilibrium Steady State

    Indian Academy of Sciences (India)

    Avinash A. Deshpande

    2017-09-12

    Sep 12, 2017 ... Abstract. We report the results of our numerical simulation of classical-dissipative dynamics of a charged particle subjected to a non-Markovian stochastic forcing. We find that the system develops a steady-state orbital magnetic moment in the presence of a static magnetic field. Very significantly, the sign of ...

  5. A steady state model for anaerobic digestion of sewage sludges ...

    African Journals Online (AJOL)

    A steady state model for anaerobic digestion of sewage sludge is developed that comprises three sequential parts – a kinetic part from which the % COD removal and ... and a carbonate system weak acid/base chemistry part from which the digester pH is calculated from the partial pressure of CO2 and alkalinity generated.

  6. Steady States of the Parametric Rotator and Pendulum

    Science.gov (United States)

    Bouzas, Antonio O.

    2010-01-01

    We discuss several steady-state rotation and oscillation modes of the planar parametric rotator and pendulum with damping. We consider a general elliptic trajectory of the suspension point for both rotator and pendulum, for the latter at an arbitrary angle with gravity, with linear and circular trajectories as particular cases. We treat the…

  7. Practical error analysis of the quasi-steady-state approximation ...

    African Journals Online (AJOL)

    The Quasi-Steady-State Approximation (QSSA) is a method of getting approximate solutions to differential equations, developed heuristically in biochemistry early this century. It can produce acceptable and important results even when formal analytic and numerical procedures fail. It has become associated with singular ...

  8. Regulation of the tolerogenic function of steady-state DCs.

    Science.gov (United States)

    Probst, Hans Christian; Muth, Sabine; Schild, Hansjörg

    2014-04-01

    Dendritic cells (DCs) are master regulators of T-cell responses. After sensing pathogen-derived molecular patterns (PAMPs), or signals of inflammation and cellular stress, DCs differentiate into potent activators of naïve CD4(+) and CD8(+) T cells through a process that is termed DC maturation. By contrast, DCs induce and maintain peripheral T-cell tolerance in the steady state, that is in the absence of overt infection or inflammation. However, the immunological steady state is not devoid of DC-activating stimuli, such as commensal microorganisms, subclinical infections, or basal levels of proinflammatory mediators. In the presence of these activating stimuli, DC maturation must be calibrated to ensure self-tolerance yet allow for adequate T-cell responses to infections. Here, we review the factors that are known to control DC maturation in the steady state and discuss their effect on the tolerogenic function of steady-state DCs. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Classical Orbital Paramagnetism in Non-equilibrium Steady State

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... We report the results of our numerical simulation of classical-dissipative dynamics of a charged particle subjected to a non-Markovian stochastic forcing. We find that the system develops a steady-state orbital magnetic moment in the presence of a static magnetic field. Very significantly, the sign of the orbital ...

  10. Dark Entangled Steady States of Interacting Rydberg Atoms

    DEFF Research Database (Denmark)

    Dasari, Durga; Mølmer, Klaus

    2013-01-01

    their short-lived excited states lead to rapid, dissipative formation of an entangled steady state. We show that for a wide range of physical parameters, this entangled state is formed on a time scale given by the strengths of coherent Raman and Rabi fields applied to the atoms, while it is only weakly...

  11. A displacement based FE formulation for steady state problems

    NARCIS (Netherlands)

    Yu, Y.

    2005-01-01

    In this thesis a new displacement based formulation is developed for elasto-plastic deformations in steady state problems. In this formulation the displacements are the primary variables, which is in contrast to the more common formulations in terms of the velocities as the primary variables. In a

  12. Classical Orbital Paramagnetism in Non-equilibrium Steady State

    Indian Academy of Sciences (India)

    Avinash A. Deshpande

    2017-09-12

    Sep 12, 2017 ... Classical Orbital Paramagnetism in Non-equilibrium Steady State. AVINASH A. DESHPANDE. ∗ and N. KUMAR. Raman Research Institute, Bangalore 560 080, India. ∗. Corresponding author. E-mail: desh@rri.res.in. MS received 25 March 2017; accepted 31 July 2017; published online 12 September ...

  13. Dust remobilization in fusion plasmas under steady state conditions

    NARCIS (Netherlands)

    Tolias, P.; Ratynskaia, S.; de Angeli, M.; De Temmerman, G.; Ripamonti, D.; Riva, G.; I. Bykov,; Shalpegin, A.; Vignitchouk, L.; Brochard, F.; Bystrov, K.; Bardin, S.; Litnovsky, A.

    2016-01-01

    The first combined experimental and theoretical studies of dust remobilization by plasma forces are reported. The main theoretical aspects of remobilization in fusion devices under steady state conditions are analyzed. In particular, the dominant role of adhesive forces is highlighted and generic

  14. Steady-state Operational Characteristics of Ghana Research ...

    African Journals Online (AJOL)

    Steady state operational characteristics of the 30 kW tank-in-pool type reactor named Ghana Research Reactor-1 were investigated after a successful on-site zero power critical experiments. The steadystate operational character-istics determined were the thermal neutron fluxes, maximum period of operation at nominal ...

  15. Optimising performance in steady state for a supermarket refrigeration system

    DEFF Research Database (Denmark)

    Green, Torben; Kinnaert, Michel; Razavi-Far, Roozbeh

    2012-01-01

    Using a supermarket refrigeration system as an illustrative example, the paper postulates that by appropriately utilising knowledge of plant operation, the plant wide performance can be optimised based on a small set of variables. Focusing on steady state operations, the total system performance...

  16. Stabilizing the border steady-state solution of two interacting ...

    African Journals Online (AJOL)

    In this paper, we have successfully developed a feedback control which has been used to stabilize an unstable steady-state solution (0, 3.3534). This convergence has occurred when the values of the final time are 190, 200, 210 and 220 which corresponds to the scenario when the value of the step length of our simulation ...

  17. Steady state evaluation of aortic dissections: a feasibility study

    International Nuclear Information System (INIS)

    De Cicco, Maria Luisa; Andreoli, Chiara; Casciani, Emanuele; Polettini, Elisabetta; Gualdi, Gian Franco

    2005-01-01

    Purpose. One the main reasons for the limited use of MR1 in the evaluation of aortic dissection in emergency conditions is its long execution lime. The authors report their experience regarding a new MRI sequence that reduces execution time and avoids the use of contrast medium. Materials and methods. Eighteen haemodynamically stable patients with suspected (16 cases, 3 with confirmed diagnosis of aneurysm) or known aortic dissection (2 cases) underwent in emergency conditions 1.5T MR1 with Steady-State sequence (Fast Imaging Employing Steady-State Acquisition: GRE 2D; TR 3.5, TE 1.6; Flip Angle 45, bandwidth 125, matrix 224x224, NEX 1, acquisition lime per slice 7 s, thickness 6-8 mm, FOV 38; 2D-OE breath-hold sequence requiring cardiac triggering). The results obtained were compared in terms of diagnostic accuracy and execution lime wth those of classical MRI examination (black blood TI, FSE T2 and 3D MR-angiography) or multislice CT. Results. The diagnostic accuracy of MRI, both with Steady-State sequence and the classical technique, and multislice CT in the diagnosis of dissection or aneurysm equal (100%), whereas execution time is 6, 25 and 6 minutes, respectively. Multislice CT proved to be more accurate than Steady-State MR1 in evaluating the renal parenchyma and the extension of the dissection to the renal arteries. Conclusions. The Steady-State MRI sequence provides a diagnosis of aortic dissection or aneurysmal dilatation in a short lime and may represent a valuable alternative to CT in emergency settings, especially in patients with reported contraindications to iodinated contrast media [it

  18. Auditory steady-state response in cochlear implant patients.

    Science.gov (United States)

    Torres-Fortuny, Alejandro; Arnaiz-Marquez, Isabel; Hernández-Pérez, Heivet; Eimil-Suárez, Eduardo

    2018-03-19

    Auditory steady state responses to continuous amplitude modulated tones at rates between 70 and 110Hz, have been proposed as a feasible alternative to objective frequency specific audiometry in cochlear implant subjects. The aim of the present study is to obtain physiological thresholds by means of auditory steady-state response in cochlear implant patients (Clarion HiRes 90K), with acoustic stimulation, on free field conditions and to verify its biological origin. 11 subjects comprised the sample. Four amplitude modulated tones of 500, 1000, 2000 and 4000Hz were used as stimuli, using the multiple frequency technique. The recording of auditory steady-state response was also recorded at 0dB HL of intensity, non-specific stimulus and using a masking technique. The study enabled the electrophysiological thresholds to be obtained for each subject of the explored sample. There were no auditory steady-state responses at either 0dB or non-specific stimulus recordings. It was possible to obtain the masking thresholds. A difference was identified between behavioral and electrophysiological thresholds of -6±16, -2±13, 0±22 and -8±18dB at frequencies of 500, 1000, 2000 and 4000Hz respectively. The auditory steady state response seems to be a suitable technique to evaluate the hearing threshold in cochlear implant subjects. Copyright © 2018 Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. Publicado por Elsevier España, S.L.U. All rights reserved.

  19. Steady-state nucleate pool boiling mechanism at low heat fluxes

    International Nuclear Information System (INIS)

    Bastos, L.E.G.

    1979-01-01

    Heat is transfered in the steady state to a horizontal cooper disc inmersed in water at saturation temperature. Levels of heat flux are controlled so that convection and the nucleate boiling can be observed. The value of heat flux is determined experimentally and high speed film is used to record bubble growth. In order to explain the phenomenon the oretical model is proposed in which part of the heat is transfered by free convection during nucleate boiling regime. Agreement between the experiments and the theoretical model is good. (Author) [pt

  20. Ozone mass transfer and kinetics experiments

    International Nuclear Information System (INIS)

    Bollyky, L.J.; Beary, M.M.

    1981-12-01

    Experiments were conducted at the Hanford Site to determine the most efficient pH and temperature levels for the destruction of complexants in Hanford high-level defense waste. These complexants enhance migration of radionuclides in the soil and inhibit the growth of crystals in the evaporator-crystallizer. Ozone mass transfer and kinetics tests have been outlined for the determination of critical mass transfer and kinetics parameters of the ozone-complexant reaction

  1. Mass Transfer Operations for the Practicing Engineer

    CERN Document Server

    Theodore, Louis

    2011-01-01

    Part of the Essential Engineering Calculations Series, this book presents step-by-step solutions of the basic principles of mass transfer operations, including sample problems and solutions and their applications, such as distillation, absorption, and stripping. Presenting the subject from a strictly pragmatic point of view, providing both the principles of mass transfer operations and their applications, with clear instructions on how to carry out the basic calculations needed, the book also covers topics useful for readers taking their professional exams.

  2. An equation oriented approach to steady state flowsheeting of methanol synthesis loop

    International Nuclear Information System (INIS)

    Fathikalajahi, J.; Baniadam, M.; Rahimpour, M.R.

    2008-01-01

    An equation-oriented approach was developed for steady state flowsheeting of a commercial methanol plant. The loop consists of fixed bed reactor, flash separator, preheater, coolers, and compressor. For steady sate flowsheeting of the plant mathematical model of reactor and other units are needed. Reactor used in loop is a Lurgi type and its configuration is rather complex. Previously reactor and flash separator are modeled as two important units of plant. The model is based on mass and energy balances in each equipment and utilizing some auxiliary equations such as rate of reaction and thermodynamics model for activity coefficients of liquid. In order to validate the mathematical model for the synthesis loop, some simulation data were performed using operating conditions and characteristics of the commercial plant. The good agreement between the steady state simulation results and the plant data shows the validity of the model

  3. Basic heat and mass transfer

    CERN Document Server

    Mills, A F

    1999-01-01

    The Second Edition offers complete coverage of heat transfer with broad up-to-date coverage that includes an emphasis on engineering relevance and on problem solving. Integrates software to assist the reader in efficiently calculations. Carefully orders material to make book more reader-friendly and accessible. Offers an extensive introduction to heat exchange design to enhance the engineering and design content of course to satisfy ABET requirements. For professionals in engineering fields.

  4. 40 CFR 92.130 - Determination of steady-state concentrations.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Determination of steady-state....130 Determination of steady-state concentrations. (a)(1) For HC and NOX emissions, a steady-state... section. (2) For CO and CO2 emissions, a steady-state concentration measurement, measured after 300...

  5. Catalytic Mechanism of Cruzain from Trypanosoma cruzi As Determined from Solvent Kinetic Isotope Effects of Steady-State and Pre-Steady-State Kinetics.

    Science.gov (United States)

    Zhai, Xiang; Meek, Thomas D

    2018-02-02

    Cruzain, an important drug target for Chagas disease, is a member of clan CA of the cysteine proteases. Understanding the catalytic mechanism of cruzain is vital to the design of new inhibitors. To this end, we have determined pH-rate profiles for substrates and affinity agents and solvent kinetic isotope effects in pre-steady-state and steady-state modes using three substrates: Cbz-Phe-Arg-AMC, Cbz-Arg-Arg-AMC, and Cbz-Arg-Ala-AMC. The pH-rate profile of k cat /K m for Cbz-Arg-Arg-AMC indicated pK 1 = 6.6 (unprotonated) and pK 2 ∼ 9.6 (protonated) groups were required for catalysis. The temperature dependence of the pK = 6.2-6.6 group exhibited a ΔH ion value of 8.4 kcal/mol, typical of histidine. The pH-rate profile of inactivation by iodoacetamide confirmed that the catalytic cysteine possesses a pK a of 9.8. Normal solvent kinetic isotope effects were observed for both D 2 O k cat (1.6-2.1) and D 2 O k cat /K m (1.1-1.4) for all three substrates. Pre-steady-state kinetics revealed exponential bursts of AMC production for Cbz-Phe-Arg-AMC and Cbz-Arg-Arg-AMC, but not for Cbz-Arg-Ala-AMC. The overall solvent isotope effect on k cat can be attributed to the solvent isotope effect on the deacylation step. Our results suggest that cruzain is unique among papain-like cysteine proteases in that the catalytic cysteine and histidine have neutral charges in the free enzyme. The generation of the active thiolate of the catalytic cysteine is likely preceded (and possibly triggered) by a ligand-induced conformational change, which could bring the catalytic dyad into the proximity to effect proton transfer.

  6. Reliability of heart rate responses to non-steady-state activities of daily living in men with spinal cord injuries

    NARCIS (Netherlands)

    Janssen, T W; van Oers, C A; van der Woude, L H; Hollander, A P

    The reliability of heart rate responses to non-steady-state tasks among 37 men with spinal cord injuries (lesion level: C4/5-L5) was examined with a simple heart rate recording device (Sport Tester PE3000). Three identical trials of 6 different transfers and an 8-cm curb ascent were performed on one

  7. The pre-steady state reaction of ferrocytochrome c with the cytochrome c-cytochrome aa3 complex

    NARCIS (Netherlands)

    Veerman, E.C.I.; Wilms, J.; Casteleijn, G.; Gelder, B.F. van

    1980-01-01

    1. Using stopped-flow technique we have investigated the electron transfer form cytochrome c to cytochrome aa3 and to the (porphyrin) cytochrome c-cytochromeaa3 complex. 2. In a low ionic strength medium, the pre-steady state reaction occurs in a biphasic way with rate constants of at least 2 ·

  8. The mass energy transfer and mass absorption coefficients

    International Nuclear Information System (INIS)

    Tomljenovic, I.; Stankovic, S.; Ninkovic, M.

    2002-01-01

    The calculation of the mass energy transfer and the mass absorption coefficients is presented and data for their change by energy, in range from 0,01 MeV to 10 MeV, are given. Data are numerically and graphically presented for following materials: air, water, polyethylene, lucite and polystyrene (author)

  9. Steady-state propagation of interface corner crack

    DEFF Research Database (Denmark)

    Veluri, Badrinath; Jensen, Henrik Myhre

    2013-01-01

    Steady-state propagation of interface cracks close to three-dimensional corners has been analyzed. Attention was focused on modeling the shape of the interface crack front and calculating the critical stress for steady-state propagation of the crack. The crack propagation was investigated...... by estimating the fracture mechanics parameters that includes the strain energy release rate, crack front profiles and the three-dimensional mode-mixity along the interface crack front. A numerical approach was then applied for coupling the far field solutions based on the Finite Element Method to the near...... field (crack tip) solutions based on the J-integral. The adopted two-dimensional numerical approach for the calculation of fracture mechanical properties was compared with three-dimensional models for quarter-circular and straight sided crack front shapes. A quantitative approach was formulated based...

  10. Theory of minimum dissipation of energy for the steady state

    International Nuclear Information System (INIS)

    Chu, T.K.

    1992-02-01

    The magnetic configuration of an inductively driven steady-state plasma bounded by a surface (or two adjacent surfaces) on which B·n = 0 is force-free: ∇xB = 2αB, where α is a constant, in time and in space. α is the ratio of the Poynting flux to the magnetic helicity flux at the boundary. It is also the ratio of the dissipative rates of the magnetic energy to the magnetic helicity in the plasma. The spatial extent of the configuration is noninfinitesimal. This global constraint is a result of the requirement that, for a steady-state plasma, the rate of change of the vector potential, ∂A/∂t, is constant in time and uniform in space

  11. Theoretical analysis of steady state operating forces in control valves

    Directory of Open Access Journals (Sweden)

    Basavaraj Hubballi

    2018-01-01

    Full Text Available The controlling components, such as valves are used to regulate controlled fluid power. It is not always possible to calculate valve forces accurately, and with some types of valves even the existence of certain types of forces cannot be predicted with certainty. In many cases, however, the analysis can be made fairly completely and accurately. The assumption of steady state conditions is valid for the valve alone, but transient effects in the rest of the system may be large. These effects are particularly important with regard to the instability of valves, where the system may react on the valve in such a way as to make it squeal or oscillate, sometimes with large amplitude. The origin of the steady state flow force understood from a brief qualitative explanation. The following paper will summarize much of what is known about valve forces in the spool type controlling element.

  12. Quantally fed steady-state domain distributions in stochastic inflation

    International Nuclear Information System (INIS)

    Bellini, M.; Sisterna, P.D.; Deza, R.R.

    2000-01-01

    Within the framework of stochastic inflationary cosmology it has been derived steady-state distributions P c (V) of domains in comoving coordinates, under the assumption of slow-rolling and for two specific choices of the coarse-grained inflation potential V(Φ). It has been modelled the process as a Starobinsky-like equation in V-space plus a time-independent source term P ω (V) which carries (phenomenologically) quantum-mechanical information drawn from either of two known solutions of the Wheeler-De Witt equation: Hartle-Hawking's and Vilenkin's wave functions. The presence of the source term leads to the existence of nontrivial steady-state distributions P c ω (V). The relative efficiencies of both mechanisms at different scales are compared for the proposed potentials

  13. Non-equilibrium steady states in supramolecular polymerization

    Science.gov (United States)

    Sorrenti, Alessandro; Leira-Iglesias, Jorge; Sato, Akihiro; Hermans, Thomas M.

    2017-06-01

    Living systems use fuel-driven supramolecular polymers such as actin to control important cell functions. Fuel molecules like ATP are used to control when and where such polymers should assemble and disassemble. The cell supplies fresh ATP to the cytosol and removes waste products to sustain steady states. Artificial fuel-driven polymers have been developed recently, but keeping them in sustained non-equilibrium steady states (NESS) has proven challenging. Here we show a supramolecular polymer that can be kept in NESS, inside a membrane reactor where ATP is added and waste removed continuously. Assembly and disassembly of our polymer is regulated by phosphorylation and dephosphorylation, respectively. Waste products lead to inhibition, causing the reaction cycle to stop. Inside the membrane reactor, however, waste can be removed leading to long-lived NESS conditions. We anticipate that our approach to obtain NESS can be applied to other stimuli-responsive materials to achieve more life-like behaviour.

  14. Steady State Dynamic Operating Behavior of Universal Motor

    Directory of Open Access Journals (Sweden)

    Muhammad Khan Burdi

    2015-01-01

    Full Text Available A detailed investigation of the universal motor is developed and used for various dynamic steady state and transient operating conditions of loads. In the investigation, output torque, motor speed, input current, input/output power and efficiency are computed, compared and analyzed for different loads. While this paper discusses the steady-state behavior of the universal motor, another companion paper, ?Transient dynamic behavior of universal motor?, will discuss its transient behavior in detail. A non-linear generalized electric machine model of the motor is considered for the analysis. This study was essential to investigate effect of output load on input current, power, speed and efficiency of the motor during operations. Previously such investigation is not known

  15. Extending Molecular Theory to Steady-State Diffusing Systems

    Energy Technology Data Exchange (ETDEWEB)

    FRINK,LAURA J. D.; SALINGER,ANDREW G.; THOMPSON,AIDAN P.

    1999-10-22

    Predicting the properties of nonequilibrium systems from molecular simulations is a growing area of interest. One important class of problems involves steady state diffusion. To study these cases, a grand canonical molecular dynamics approach has been developed by Heffelfinger and van Swol [J. Chem. Phys., 101, 5274 (1994)]. With this method, the flux of particles, the chemical potential gradients, and density gradients can all be measured in the simulation. In this paper, we present a complementary approach that couples a nonlocal density functional theory (DFT) with a transport equation describing steady-state flux of the particles. We compare transport-DFT predictions to GCMD results for a variety of ideal (color diffusion), and nonideal (uphill diffusion and convective transport) systems. In all cases excellent agreement between transport-DFT and GCMD calculations is obtained with diffusion coefficients that are invariant with respect to density and external fields.

  16. Optimal control of transitions between nonequilibrium steady states.

    Directory of Open Access Journals (Sweden)

    Patrick R Zulkowski

    Full Text Available Biological systems fundamentally exist out of equilibrium in order to preserve organized structures and processes. Many changing cellular conditions can be represented as transitions between nonequilibrium steady states, and organisms have an interest in optimizing such transitions. Using the Hatano-Sasa Y-value, we extend a recently developed geometrical framework for determining optimal protocols so that it can be applied to systems driven from nonequilibrium steady states. We calculate and numerically verify optimal protocols for a colloidal particle dragged through solution by a translating optical trap with two controllable parameters. We offer experimental predictions, specifically that optimal protocols are significantly less costly than naive ones. Optimal protocols similar to these may ultimately point to design principles for biological energy transduction systems and guide the design of artificial molecular machines.

  17. Conjugate heat and mass transfer in heat mass exchanger ducts

    CERN Document Server

    Zhang, Li-Zhi

    2013-01-01

    Conjugate Heat and Mass Transfer in Heat Mass Exchanger Ducts bridges the gap between fundamentals and recent discoveries, making it a valuable tool for anyone looking to expand their knowledge of heat exchangers. The first book on the market to cover conjugate heat and mass transfer in heat exchangers, author Li-Zhi Zhang goes beyond the basics to cover recent advancements in equipment for energy use and environmental control (such as heat and moisture recovery ventilators, hollow fiber membrane modules for humidification/dehumidification, membrane modules for air purification, desi

  18. Mimicking Nonequilibrium Steady States with Time-Periodic Driving

    Science.gov (United States)

    2016-08-29

    8,9]: A reaction such as ATP hydrolysis ( ATP → ADPþ Pi) produces entropy in the surrounding solution, and the chemical potential difference between...kinetic proofreading is achieved through breaking detailed balance, e.g., coupling the w ↔ x transition to the hydrolysis of ATP into ADP , whose...paradigm, a system driven by fixed thermodynamic forces—such as temperature gradients or chemical potential differences — reaches a steady state in

  19. Three-dimensional stellarator equilibrium as an ohmic steady state

    International Nuclear Information System (INIS)

    Park, W.; Monticello, D.A.; Strauss, H.; Manickam, J.

    1985-07-01

    A stable three-dimensional stellarator equilibrium can be obtained numerically by a time-dependent relaxation method using small values of dissipation. The final state is an ohmic steady state which approaches an ohmic equilibrium in the limit of small dissipation coefficients. We describe a method to speed up the relaxation process and a method to implement the B vector . del p = 0 condition. These methods are applied to obtain three-dimensional heliac equilibria using the reduced heliac equations

  20. Visual steady state in relation to age and cognitive function

    DEFF Research Database (Denmark)

    Horwitz, Anna; Dyhr Thomsen, Mia; Wiegand, Iris

    2017-01-01

    examine the steady-state VEP power response (SSVEP-PR) in the alpha (8Hz) and gamma (36Hz) bands in 54 males (avg. age: 62.0 years) and compare these with 10 young healthy participants (avg. age 27.6 years). Furthermore, we correlate the individual alpha-to-gamma difference in relative visual-area power......, global cognition, executive function, memory, and education (p

  1. Numerical study of heat and mass transfer during evaporation of a thin liquid film

    Directory of Open Access Journals (Sweden)

    Oubella M’hand

    2015-01-01

    Full Text Available A numerical study of mixed convection heat and mass transfer with film evaporation in a vertical channel is developed. The emphasis is focused on the effects of vaporization of three different liquid films having widely different properties, along the isothermal and wetted walls on the heat and mass transfer rates in the channel. The induced laminar downward flow is a mixture of blowing dry air and vapour of water, methanol or acetone, assumed as ideal gases. A two-dimensional steady state and elliptical flow model, connected with variable thermo-physical properties, is used and the phase change problem is based on thin liquid film assumptions. The governing equations of the model are solved by a finite volume method and the velocity-pressure fields are linked by SIMPLE algorithm. The numerical results, including the velocity, temperature and concentration profiles, as well as axial variations of Nusselt numbers, Sherwood number and dimensionless film evaporation rate are presented for two values of inlet temperature and Reynolds number. It was found that lower the inlet temperature and Re, the higher the induced flows cooling with respect of most volatile film. The better mass transfer rates related with film evaporation are found for a system with low mass diffusion coefficient.

  2. Constant specific activity input allows reconstruction of endogenous glucose concentration in non-steady state

    International Nuclear Information System (INIS)

    Cobelli, C.; Toffolo, G.

    1990-01-01

    In vivo studies on the glucose system often require its perturbation by an exogenous input of glucose, whereas glucose turnover is assessed by infusing a glucose tracer. The constant infusion represents the usual format of tracer administration, but it has no clear advantage other than simplicity. Here we propose a different tracer infusion format. It consists of infusing the tracer in parallel with unlabeled glucose so as to maintain a constant specific activity in the infusate. This protocol does not increase experimental complexity and provides new information on the glucose system in non-steady state by allowing reconstruction of the endogenous component of glucose concentration. This reconstruction only requires very general assumptions, such as tracer-tracee indistinguishability and mass conservation; in particular it is independent of the glucose model structure, i.e., number of compartments and their interconnections. A proof of the result is given for a general nonlinear model of the glucose system. The constant specific activity input is also advantageous for non-steady-state calculations, because it reduces the variation in the measured plasma glucose specific activity. The glucose system has served as the prototype, but the protocol is applicable to other blood-borne substances. The radioactive tracer case has been considered, but the same results apply to stable isotope tracers as well; in this case they also become relevant in a somewhat different context, i.e., kinetic studies in steady state

  3. Progress and prospect of true steady state operation with RF

    Directory of Open Access Journals (Sweden)

    Jacquinot Jean

    2017-01-01

    Full Text Available Operation of fusion confinement experiments in full steady state is a major challenge for the development towards fusion energy. Critical to achieving this goal is the availability of actively cooled plasma facing components and auxiliary systems withstanding the very harsh plasma environment. Equally challenging are physics issues related to achieving plasma conditions and current drive efficiency required by reactor plasmas. RF heating and current drive systems have been key instruments for obtaining the progress made until today towards steady state. They hold all the records of long pulse plasma operation both in tokamaks and in stellarators. Nevertheless much progress remains to be made in particular for integrating all the requirements necessary for maintaining in steady state the density and plasma pressure conditions of a reactor. This is an important stated aim of ITER and of devices equipped with superconducting magnets. After considering the present state of the art, this review will address the key issues which remain to be solved both in physics and technology for reaching this goal. They constitute very active subjects of research which will require much dedicated experimentation in the new generation of superconducting devices which are now in operation or becoming close to it.

  4. Steady states of continuous-time open quantum walks

    Science.gov (United States)

    Liu, Chaobin; Balu, Radhakrishnan

    2017-07-01

    Continuous-time open quantum walks (CTOQW) are introduced as the formulation of quantum dynamical semigroups of trace-preserving and completely positive linear maps (or quantum Markov semigroups) on graphs. We show that a CTOQW always converges to a steady state regardless of the initial state when a graph is connected. When the graph is both connected and regular, it is shown that the steady state is the maximally mixed state. As shown by the examples in this article, the steady states of CTOQW can be very unusual and complicated even though the underlying graphs are simple. The examples demonstrate that the structure of a graph can affect quantum coherence in CTOQW through a long-time run. Precisely, the quantum coherence persists throughout the evolution of the CTOQW when the underlying topology is certain irregular graphs (such as a path or a star as shown in the examples). In contrast, the quantum coherence will eventually vanish from the open quantum system when the underlying topology is a regular graph (such as a cycle).

  5. Optimization of steady-state beam-driven tokamak reactors

    International Nuclear Information System (INIS)

    Mikkelsen, D.R.; Singer, C.E.

    1983-01-01

    Recent developments in neutral beam technology prompt us to reconsider the prospects for steady-state tokamak reactors. A mathematical reactor model is developed that includes the physics of beam-driven currents and reactor power balance, as well as reactor and beam system costs. This model is used to find the plasma temperatures that minimize the reactor cost per unit of net electrical output. The optimum plasma temperatures are nearly independent of β and are roughly twice as high as the optimum temperatures for ignited reactors. If beams of neutral deuterium atoms with near-optimum energies of 1 to 2 MeV are used to drive the current in a reactor the size of the International Tokamak Reactor, then the optimum temperatures are typically T /SUB e/ approx. = 12 to 15 keV and T /SUB i/ approx. = 17 to 21 keV for a wide range of model parameters. Net electrical output rises rapidly with increasing deuterium beam energy for E /SUB b/ less than or equal to 400 keV, but rises only slowly above E /SUB b/ about 1 MeV. We estimate that beam-driven steady-state reactors could be economically competitive with pulsed-ignition reactors if cyclic-loading problems limit the toroidal magnetic field strength of pulsed reactors to less than or equal to 85% of that allowed in steady-state reactors

  6. Steady state ventilation regimes in multiple room buildings

    Science.gov (United States)

    Flynn, Morris; Caulfield, Colm-Cille

    2004-11-01

    The ventilation of connected chambers offers a rich variety of flow behaviors. A two-chamber model is considered in which only one of the chambers is thermally forced yet both may communicate with the external environment. If the plume source has a finite volume flux, either chamber may become blocked i.e. completely filled with contaminated fluid. Hence, a steady, naturally ventilated regime is possible only for certain non-dimensional combinations of the effective vent area and the source volume and buoyancy fluxes. Steady state conditions are derived in a manner analogous to Linden, Lane-Serff & Smeed (1990) and Woods, Caulfield & Phillips (2003). Unfortunately, these conditions cannot specify the buoyant layer depth in the unforced room for which the transient evolution toward steady state must also be considered. Results from this analysis (performed in the limiting case of a plume source with zero volume flux) suggest that at steady state, the buoyant layer depth in the unforced chamber may be either larger or smaller than that of the forced chamber.

  7. Steady-state oxygen-solubility in niobium

    International Nuclear Information System (INIS)

    Schulze, K.; Jehn, H.

    1977-01-01

    During annealing of niobium in oxygen in certain temperature and pressure ranges steady states are established between the absorption of molecular oxygen and the evaporation of volatile oxides. The oxygen concentration in the niobium-oxygen α-solid solution is a function of oxygen pressure and temperature and has been redetermined in the ranges 10 -5 - 10 -2 Pa O 2 and 2,070 - 2,470 K. It follows differing from former results the equation csub(o) = 9.1 x 10 -6 x sub(po2) x exp (502000/RT) with csub(o) in at.-ppm, sub(po2) in Pa, T in K, R = 8.31 J x mol -1 x K -1 . The existence of steady states is limited to a temperature range from 1870 to 2470 K and to oxygen concentrations below the solubility limit given by solidus and solvus lines in the T-c diagram. In the experiments high-purity niobium wires with a specific electrical ratio rho (273 K)/rho(4.2 K) > 5,000 have been gassed under isothermal-isobaric conditions until the steady state has been reached. The oxygen concentration has been determined analytically by vacuum fusion extraction with platinum-flux technique as well as by electrical residual resistivity measurements at 4.2 K. (orig.) [de

  8. Transient and steady-state currents in epoxy resin

    International Nuclear Information System (INIS)

    Guillermin, Christophe; Rain, Pascal; Rowe, Stephen W

    2006-01-01

    Charging and discharging currents have been measured in a diglycidyl ether of bisphenol-A epoxy resin with and without silica fillers, below and above its glass transition temperature T g = 65 deg. C. Both transient and steady-state current densities have been analysed. The average applied fields ranged from 3 to 35 kV mm -1 with a sample thickness of 0.5 mm. Above T g , transient currents suggested a phenomenon of charge injection forming trapped space charges even at low fields. Steady-state currents confirmed that the behaviour was not Ohmic and suggested Schottky-type injection. Below T g , the current is not controlled by the metal-dielectric interface but by the conduction in the volume: the current is Ohmic at low fields and both transient and steady-state currents suggest a phenomenon of space-charge limited currents at high fields. The field threshold is similar in the filler-free and the filled resin. Values in the range 12-17 kV mm -1 have been measured

  9. Heat or mass transfer from a sphere in Stokes flow at low Péclet number

    KAUST Repository

    Bell, Christopher G.

    2013-04-01

    We consider the low Péclet number, Pe≪1, asymptotic solution for steady-state heat or mass transfer from a sphere immersed in Stokes flow with a Robin boundary condition on its surface, representing Newton cooling or a first-order chemical reaction. The application of Van Dyke\\'s rule up to terms of O(Pe3) shows that the O(Pe3logPe) terms in the expression for the average Nusselt/Sherwood number are twice those previously derived in the literature. Inclusion of the O(Pe3) terms is shown to increase the range of validity of the expansion. © 2012 Elsevier Ltd. All rights reserved.

  10. The Stability of the Steady State and Bistable Response of a Flexible Rotor Supported on Squeeze Film Dampers

    Science.gov (United States)

    Meng, Guang

    1991-01-01

    The stability of the steady state response, the bistable response, and the jumping characteristics are analyzed for the case when a system accelerates or decelerates through the bistable region of a flexible rotor-centralized squeeze film damper system. It was found that the system steady state responses have two unstable regions. The larger the unbalance parameter and the smaller the bearing parameter and the external damping ratio, the easier it is for the system to lose stability. The larger the mass ratio and the smaller the stiffness ratio, the lower the threshold rotating speed of instability. The instability of the system steady-state response determined here is due to the system nonsynchronous response in many cases.

  11. Mass Transfer in Mira-Type Binaries

    Directory of Open Access Journals (Sweden)

    Mohamed S.

    2012-06-01

    Full Text Available Detached, symbiotic binaries are generally assumed to interact via Bondi-Hoyle-Littleton (BHL wind accretion. However, the accretion rates and outflow geometries that result from this mass-transfer mechanism cannot adequately explain the observations of the nearest and best studied symbiotic binary, Mira, or the formation of some post-AGB binaries, e.g. barium stars. We propose a new mass-transfer mode for Mira-type binaries, which we call ‘wind Roche-lobe overflow’ (WRLOF, and which we demonstrate with 3D hydrodynamic simulations. Importantly, we show that the circumstellar outflows which result from WRLOF tend to be highly aspherical and strongly focused towards the binary orbital plane. Furthermore, the subsequent mass-transfer rates are at least an order of magnitude greater than the analogous BHL values. We discuss the implications of these results for the shaping of bipolar (proto-planetary nebulae and other related systems.

  12. Heat or mass transfer at low Péclet number for Brinkman and Darcy flow round a sphere

    KAUST Repository

    Bell, Christopher G.

    2014-01-01

    Prior research into the effect of convection on steady-state mass transfer from a spherical particle embedded in a porous medium has used the Darcy model to describe the flow. However, a limitation of the Darcy model is that it does not account for viscous effects near boundaries. Brinkman modified the Darcy model to include these effects by introducing an extra viscous term. Here we investigate the impact of this extra viscous term on the steady-state mass transfer from a sphere at low Péclet number, Pe 1. We use singular perturbation techniques to find the approximate asymptotic solution for the concentration profile. Mass-release from the surface of the sphere is described by a Robin boundary condition, which represents a first-order chemical reaction. We find that a larger Brinkman viscous boundary layer renders mass transport by convection less effective, and reduces the asymmetry in the peri-sphere concentration profiles. We provide simple analytical expressions that can be used to calculate the concentration profiles, as well as the local and average Sherwood numbers; and comparison to numerical simulations verifies the order of magnitude of the error in the asymptotic expansions. In the appropriate limits, the asymptotic results agree with solutions previously obtained for Stokes and Darcy flow. The solution for Darcy flow with a Robin boundary condition has not been considered previously in the literature and is a new result. Whilst the article has been formulated in terms of mass transfer, the analysis is also applicable to heat transfer, with concentration replaced by temperature and the Sherwood number by the Nusselt number. © 2013 Elsevier Ltd. All rights reserved.

  13. Convective mass transfer around a dissolving bubble

    Science.gov (United States)

    Duplat, Jerome; Grandemange, Mathieu; Poulain, Cedric

    2017-11-01

    Heat or mass transfer around an evaporating drop or condensing vapor bubble is a complex issue due to the interplay between the substrate properties, diffusion- and convection-driven mass transfer, and Marangoni effects, to mention but a few. In order to disentangle these mechanisms, we focus here mainly on the convective mass transfer contribution in an isothermal mass transfer problem. For this, we study the case of a millimetric carbon dioxide bubble which is suspended under a substrate and dissolved into pure liquid water. The high solubility of CO2 in water makes the liquid denser and promotes a buoyant-driven flow at a high (solutal) Rayleigh number (Ra˜104 ). The alteration of p H allows the concentration field in the liquid to be imaged by laser fluorescence enabling us to measure both the global mass flux (bubble volume, contact angle) and local mass flux around the bubble along time. After a short period of mass diffusion, where the boundary layer thickens like the square root of time, convection starts and the CO2 is carried by a plume falling at constant velocity. The boundary layer thickness then reaches a plateau which depends on the bubble cross section. Meanwhile the plume velocity scales like (dV /d t )1 /2 with V being the volume of the bubble. As for the rate of volume loss, we recover a constant mass flux in the diffusion-driven regime followed by a decrease in the volume V like V2 /3 after convection has started. We present a model which agrees well with the bubble dynamics and discuss our results in the context of droplet evaporation, as well as high Rayleigh convection.

  14. Fitting Boolean networks from steady state perturbation data.

    Science.gov (United States)

    Almudevar, Anthony; McCall, Matthew N; McMurray, Helene; Land, Hartmut

    2011-10-05

    Gene perturbation experiments are commonly used for the reconstruction of gene regulatory networks. Typical experimental methodology imposes persistent changes on the network. The resulting data must therefore be interpreted as a steady state from an altered gene regulatory network, rather than a direct observation of the original network. In this article an implicit modeling methodology is proposed in which the unperturbed network of interest is scored by first modeling the persistent perturbation, then predicting the steady state, which may then be compared to the observed data. This results in a many-to-one inverse problem, so a computational Bayesian approach is used to assess model uncertainty. The methodology is first demonstrated on a number of synthetic networks. It is shown that the Bayesian approach correctly assigns high posterior probability to the network structure and steady state behavior. Further, it is demonstrated that where uncertainty of model features is indicated, the uncertainty may be accurately resolved with further perturbation experiments. The methodology is then applied to the modeling of a gene regulatory network using perturbation data from nine genes which have been shown to respond synergistically to known oncogenic mutations. A hypothetical model emerges which conforms to reported regulatory properties of these genes. Furthermore, the Bayesian methodology is shown to be consistent in the sense that multiple randomized applications of the fitting algorithm converge to an approximately common posterior density on the space of models. Such consistency is generally not feasible for algorithms which report only single models. We conclude that fully Bayesian methods, coupled with models which accurately account for experimental constraints, are a suitable tool for the inference of gene regulatory networks, in terms of accuracy, estimation of model uncertainty, and experimental design.

  15. Mimicking Nonequilibrium Steady States with Time-Periodic Driving

    Directory of Open Access Journals (Sweden)

    O. Raz

    2016-05-01

    Full Text Available Under static conditions, a system satisfying detailed balance generically relaxes to an equilibrium state in which there are no currents. To generate persistent currents, either detailed balance must be broken or the system must be driven in a time-dependent manner. A stationary system that violates detailed balance evolves to a nonequilibrium steady state (NESS characterized by fixed currents. Conversely, a system that satisfies instantaneous detailed balance but is driven by the time-periodic variation of external parameters—also known as a stochastic pump (SP—reaches a periodic state with nonvanishing currents. In both cases, these currents are maintained at the cost of entropy production. Are these two paradigmatic scenarios effectively equivalent? For discrete-state systems, we establish a mapping between nonequilibrium stationary states and stochastic pumps. Given a NESS characterized by a particular set of stationary probabilities, currents, and entropy production rates, we show how to construct a SP with exactly the same (time-averaged values. The mapping works in the opposite direction as well. These results establish a proof of principle: They show that stochastic pumps are able to mimic the behavior of nonequilibrium steady states, and vice versa, within the theoretical framework of discrete-state stochastic thermodynamics. Nonequilibrium steady states and stochastic pumps are often used to model, respectively, biomolecular motors driven by chemical reactions and artificial molecular machines steered by the variation of external, macroscopic parameters. Our results loosely suggest that anything a biomolecular machine can do, an artificial molecular machine can do equally well. We illustrate this principle by showing that kinetic proofreading, a NESS mechanism that explains the low error rates in biochemical reactions, can be effectively mimicked by a constrained periodic driving.

  16. A steady state tokamak operation by use of magnetic monopoles

    International Nuclear Information System (INIS)

    Narihara, K.

    1991-12-01

    A steady state tokamak operation based on a magnetic monopole circuit is considered. Circulation of a chain of iron cubes which trap magnetic monopoles generates the needed loop voltage. The monopole circuit is enclosed by a series of solenoid coils in which magnetic field is feedback controlled so that the force on the circuit balance against the mechanical friction. The driving power is supplied through the current sources of poloidal, ohmic and solenoid coils. The current drive efficiency is same as that of the ohmic current drive. (author)

  17. On the minimum circulating power of steady state tokamaks

    Energy Technology Data Exchange (ETDEWEB)

    Itoh, K.; Itoh, S.; Fukuyama, A.; Yagi, M.

    1995-07-01

    Circulating power for the sustenance and profile control of the steady state tokamak plasmas is discussed. The simultaneous fulfillment of the MHD stability at high beta value, the improved confinement and the stationary equilibrium requires the rotation drive as well as the current drive. In addition to the current drive efficiency, the efficiency for the rotation drive is investigated. The direct rotation drive by the external torque, such as the case of beam injection, is not efficient enough. The mechanism and the magnitude of the spontaneous plasma rotation are studied. (author).

  18. Steady-State-Preserving Simulation of Genetic Regulatory Systems

    Directory of Open Access Journals (Sweden)

    Ruqiang Zhang

    2017-01-01

    Full Text Available A novel family of exponential Runge-Kutta (expRK methods are designed incorporating the stable steady-state structure of genetic regulatory systems. A natural and convenient approach to constructing new expRK methods on the base of traditional RK methods is provided. In the numerical integration of the one-gene, two-gene, and p53-mdm2 regulatory systems, the new expRK methods are shown to be more accurate than their prototype RK methods. Moreover, for nonstiff genetic regulatory systems, the expRK methods are more efficient than some traditional exponential RK integrators in the scientific literature.

  19. Steady State Evoked Responses as a Measure of Tracking Difficulty.

    Science.gov (United States)

    1979-11-30

    8217) STEADY STATEr OKD !~PNE SAMAUE0;1 Jun 0.-30 Sep 79\\ TRACKIN& DFCUTY: HOR~a) a CONTRACT OR GRANT NUMBER(&) 7jU1HO . F960-79-C-156//j t- 3.PRFRIG...I.CONTROLLING OFFICE NAME AND ADDRESS,,.AARAA . Air Force Office of Scientific Research -(L 13. NUMBER OF PAGES Boiling AFB DC 20332 4 14...for future research were discussed. l AA SECURITY CLASIFI ATION OF TMIS PAGE(Wha, Data tateeE UM -R-X- 3 0-02 10 STEADY STATE EVOKED RESPONSES AS A

  20. Steady-state current drive by lower hybrid waves

    International Nuclear Information System (INIS)

    Belyanskaya, N.V.; Dnestrovskii, Y.N.; Kostomarov, D.P.; Smirnov, A.P.

    1986-01-01

    Steady-state current drive in a plasma by lower-hybrid waves with a square-wave spectrum is analyzed in the linear approximation. A linearized two-dimensional kinetic equation in velocity space for the electron distribution function is reduced to a one-dimensional expansion in Legendre polynomials. A numerical solution is found for the complete equation, and an analytic solution is found for the asymptotic equation. The results can be used to determine the effect of the spectral width of the excited waves on the efficiency of the current drive. The analytic solution agrees well with the numerical solution

  1. Selective mass transfer in a membrane absorber

    Science.gov (United States)

    Okunev, A. Yu.; Laguntsov, N. I.

    2006-09-01

    A theoretical study of selective mass transfer in a plane-frame membrane absorber (contactor) has been made. A mathematical model of the process has been developed and the process of purification of a gas mixture depending on the flow parameters, the membrane, and the feeding-mixture composition has been studied with its help.

  2. MARS input data for steady-state calculation of ATLAS

    International Nuclear Information System (INIS)

    Park, Hyun Sik; Euh, D. J.; Choi, K. Y.; Kwon, T. S.; Jeong, J. J.; Baek, W. P.

    2004-12-01

    An integral effect test loop for Pressurized Water Reactors (PWRs), the ATLAS (Advanced Thermal-hydraulic Test Loop for Accident Simulation), is under construction by Thermal-Hydraulics Safety Research Division in Korea Atomic Energy Research Institute (KAERI). This report includes calculation sheets of the input for the best-estimate system analysis code, the MARS code, based on the ongoing design features of ATLAS. The ATLAS facility has been designed to have the length scale of 1/2 and area scale of 1/144 compared with the reference plant, APR1400. The contents of this report are divided into three parts: (1) core and reactor vessel, (2) steam generator and steam line, and (3) primary piping, pressurizer and reactor coolant pump. The steady-state analysis for the ATLAS facility will be performed based on these calculation sheets, and its results will be applied to the detailed design of ATLAS. Additionally, the calculation results will contribute to getting optimum test conditions and preliminary operational test conditions for the steady-state and transient experiments

  3. Plasma control issues for an advanced steady state tokamak reactor

    International Nuclear Information System (INIS)

    Moreau, D.

    2001-01-01

    This paper deals with specific control issues related to the advanced tokamak scenarios in which rather accurate tailoring of the current density profile is a requirement in connection with the steady state operation of a reactor in a high confinement optimized shear mode. It is found that adequate current profile control can be performed if real-time magnetic flux reconstruction is available through a set of dedicated diagnostics and computers, with sufficient accuracy to deduce the radial profile of the safety factor and of the internal plasma loop voltage. It is also shown that the safety factor can be precisely controlled in the outer half of the plasma through the surface loop voltage and the off-axis current drive power, but that a compromise must be made between the accuracy of the core safety factor control and the total duration of the current and fuel density ramp-up phases, so that the demonstration of the steady state reactor potential of the optimized/reversed shear concept in the Next Step device will demand pulse lengths of the order of one thousand seconds (or more for an ITER-size machine). (author)

  4. Concept study of the Steady State Tokamak Reactor (SSTR)

    International Nuclear Information System (INIS)

    1991-06-01

    The Steady State Tokamak Reactor (SSTR) concept has been proposed as a realistic fusion power reactor to be built in the near future. An overall concept of SSTR is introduced which is based on a small extension of the present day physics and technologies. The major feature of SSTR is the maximum utilization of a bootstrap current in order to reduce the power required for the steady state operation. This requirement leads to the choice of moderate current (12 MA), and high βp (2.0) for the device, which are achieved by selecting high aspect ratio (A=4) and high toroidal magnetic field (16.5 T). A negative-ion-based neutral beam injection system is used both for heating and central current drive. Notable engineering features of SSTR are: the use of a uniform vacuum vessel and periodical replacements of the first wall and blanket layers and significant reduction of the electromagnetic force with the use of functionally gradient material. It is shown that a tokamak machine comparable to ITER in size can become a power reactor capable of generating about 1 GW of electricity with a plant efficiency of ∼30%. (author)

  5. MHD stability regimes for steady state and pulsed reactors

    International Nuclear Information System (INIS)

    Jardin, S.C.; Kessel, C.E.; Pomphrey, N.

    1994-02-01

    A tokamak reactor will operate at the maximum value of β≡2μ 0 /B 2 that is compatible with MHD stability. This value depends upon the plasma current and pressure profiles, the plasma shape and aspect ratio, and the location of nearby conducting structures. In addition, a steady state reactor will minimize its external current drive requirements and thus achieve its maximum economic benefit with a bootstrap fraction near one, I bs /I p ∼ 1, which constrains the product of the inverse aspect ratio and the plasma poloidal beta to be near unity, ε β p ∼ 1. An inductively driven pulsed reactor has different constraints set by the steady-state Ohm's law which relates the plasma temperature and density profiles to the parallel current density. We present the results obtained during the ARIES I, II/IV, and III and the PULSAR reactor studies where these quantities were optimized subject to different design philosophies. The ARIES-II/IV and ARIES-III designs are both in the second stability regime, but differ in requirements on the form of the profiles at the plasma edge, and in the location of the conducting wall. The relation between these, as well as new attractive MHD regimes not utilized in the ARIES or PULSAR studies is also discussed

  6. Steady state magnetic field configurations for the earth's magnetotail

    International Nuclear Information System (INIS)

    Hau, L.N.; Wolf, R.A.; Voigt, G.H.; Wu, C.C.

    1989-01-01

    The authors present a two-dimensional, force-balanced magnetic field model in which flux tubes have constant pVγ throughout an extended region of the nightside plasma sheet, between approximately 36 R E geocentric distance and the region of the inner edge of the plasma sheet. They have thus demonstrated the theoretical existence of a steady state magnetic field configuration that is force-balanced and also consistent with slow, lossless, adiabatic, earthward convection within the limit of the ideal MHD (isotropic pressure, perfect conductivity). The numerical solution was constructed for a two-dimensional magnetosphere with a rectangular magnetopause and nonflaring tail. The primary characteristics of the steady state convection solution are (1) a pressure maximum just tailward of the inner edge of the plasma sheet and (2) a deep, broad minimum in equatorial magnetic field strength B ze , also just tailward of the inner edge. The results are consistent with Erickson's (1985) convection time sequences, which exhibited analogous pressure peaks and B ze minima. Observations do not indicate the existence of a B ze minimum, on the average. They suggest that the configurations with such deep minima in B ze may be tearing-mode unstable, thus leading to substorm onset in the inner plasma sheet

  7. True constructive interference in the steady state (trueCISS).

    Science.gov (United States)

    Hilbert, Tom; Nguyen, Damien; Thiran, Jean-Philippe; Krueger, Gunnar; Kober, Tobias; Bieri, Oliver

    2018-04-01

    To introduce a novel time-efficient method, termed true constructive interference in the steady state (trueCISS), that not only solves the problem of banding artifacts for balanced steady-state free precession (bSSFP) but also provides its genuine, that is, true, on-resonant signal. After a compressed sensing reconstruction from a set of highly undersampled phase-cycled bSSFP scans, the local off-resonance, relaxation time ratio, and equilibrium magnetization are voxel-wise estimated using a dictionary-based fitting routine. Subsequently, on-resonant bSSFP images are generated using the previously estimated parameters. Due to the high undersampling factors used, the acquisition time is not prolonged with respect to a standard CISS acquisition. From a set of 16 phase-cycled SSFP scans in combination with an eightfold undersampling, both phantom and in vivo whole-brain experiments demonstrate that banding successfully can be removed. Additionally, trueCISS allows the derivation of synthetic bSSFP images with arbitrary flip angles, which enables image contrasts that may not be possible to acquire in practice due to safety constraints. TrueCISS offers banding-free bSSFP images with on-resonant signal intensity and without requiring additional acquisition time compared to conventional methods. Magn Reson Med 79:1901-1910, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  8. Radial fast interrupted steady-state (FISS) magnetic resonance imaging.

    Science.gov (United States)

    Koktzoglou, Ioannis; Edelman, Robert R

    2018-04-01

    To report a highly interrupted radial variant of balanced steady-state free precession (bSSFP) imaging, termed fast interrupted steady-state (FISS), for decreasing flow artifact as well as fat signal conspicuity with respect to bSSFP, and saturation effects vis-à-vis fast low-angle shot (FLASH) imaging. Numerical simulations, phantom studies, and human studies were conducted to examine the imaging contrast, off-resonance behavior, and flow properties of FISS. Human studies applied FISS for cine cardiac imaging and ungated nonenhanced MR angiography (MRA) of the legs, neck, and brain. Comparisons were made with bSSFP and FLASH imaging. Simulations revealed that FISS retains the high signal levels of bSSFP for stationary on-resonant spins, while reducing undesirable signal heterogeneity from flowing spins. Phantom studies agreed with the simulations, and showed that FISS reduces fat signal and flow artifact with respect to bSSFP imaging. FISS imaging in human subjects agreed with the simulations and phantom studies, and showed reduced saturation artifact compared with FLASH imaging. FISS imaging reduces flow artifact and fat signal conspicuity with respect to bSSFP imaging, and ameliorates arterial signal saturation observed with FLASH imaging. Potential clinical applications include fat-suppressed cine imaging and ungated nonenhanced MRA. Magn Reson Med 79:2077-2086, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  9. Steady-State ALPS for Real-Valued Problems

    Science.gov (United States)

    Hornby, Gregory S.

    2009-01-01

    The two objectives of this paper are to describe a steady-state version of the Age-Layered Population Structure (ALPS) Evolutionary Algorithm (EA) and to compare it against other GAs on real-valued problems. Motivation for this work comes from our previous success in demonstrating that a generational version of ALPS greatly improves search performance on a Genetic Programming problem. In making steady-state ALPS some modifications were made to the method for calculating age and the method for moving individuals up layers. To demonstrate that ALPS works well on real-valued problems we compare it against CMA-ES and Differential Evolution (DE) on five challenging, real-valued functions and on one real-world problem. While CMA-ES and DE outperform ALPS on the two unimodal test functions, ALPS is much better on the three multimodal test problems and on the real-world problem. Further examination shows that, unlike the other GAs, ALPS maintains a genotypically diverse population throughout the entire search process. These findings strongly suggest that the ALPS paradigm is better able to avoid premature convergence then the other GAs.

  10. Transient and steady-state selection in the striatal microcircuit

    Directory of Open Access Journals (Sweden)

    Adam eTomkins

    2014-01-01

    Full Text Available Although the basal ganglia have been widely studied and implicated in signal processing and action selection, little information is known about the active role the striatal microcircuit plays in action selection in the basal ganglia-thalamo-cortical loops. To address this knowledge gap we use a large scale three dimensional spiking model of the striatum, combined with a rate coded model of the basal ganglia-thalamo-cortical loop, to asses the computational role the striatum plays in action selection. We identify a robust transient phenomena generated by the striatal microcircuit, which temporarily enhances the difference between two competing cortical inputs. We show that this transient is sufficient to modulate decision making in the basal ganglia-thalamo-cortical circuit. We also find that the transient selection originates from a novel adaptation effect in single striatal projection neurons, which is amenable to experimental testing. Finally, we compared transient selection with models implementing classical steady-state selection. We challenged both forms of model to account for recent reports of paradoxically enhanced response selection in Huntington's Disease patients. We found that steady-state selection was uniformly impaired under all simulated Huntington's conditions, but transient selection was enhanced given a sufficient Huntington's-like increase in NMDA receptor sensitivity. Thus our models provide an intriguing hypothesis for the mechanisms underlying the paradoxical cognitive improvements in manifest Huntington's patients.

  11. Parametric study of the primary and secondary systems of the CAREM-25 reactor on steady state

    International Nuclear Information System (INIS)

    Halpert, Silvia; Vazquez, Luis

    2000-01-01

    In the CAREM-25 reactor the primary coolant flows by natural convection that's why the flow is established when the balance between the buoyancy force and friction pressure drop through circuit is obtained. This paper presents a parametric study on primary and secondary systems of the reactor on steady state, for different values of some thermohydraulics parameters: safety factor on friction loss pressure calculations (f), steam generator heat transfer area (A T ) and primary pressure (P P ). The ESCAREM 2.08 thermohydraulic code, which calculates the primary system behavior for steady state conditions, was used for this study. The conclusions of this study are: -) There was a variation of the 15% on the primary coolant flow when the safety factor was changed a 50 %; -) The primary and secondary systems conditions do not change when the power is less than 100 MW; -) Between 100 and 110 MW the decrease of the heat transfer area produces an important change on the secondary systems conditions: the outlet steam generator temperature decrease and there is an important rice in the flow; -) The primary pressure could decrease up to 11.4 MPa without violating turbine requirements. (author)

  12. 40 CFR 86.1362-2010 - Steady-state testing with a ramped-modal cycle.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 19 2010-07-01 2010-07-01 false Steady-state testing with a ramped... Exhaust Test Procedures § 86.1362-2010 Steady-state testing with a ramped-modal cycle. This section describes how to test engines under steady-state conditions. For model years through 2009, manufacturers may...

  13. 40 CFR 86.1362-2007 - Steady-state testing with a ramped-modal cycle.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 19 2010-07-01 2010-07-01 false Steady-state testing with a ramped... Exhaust Test Procedures § 86.1362-2007 Steady-state testing with a ramped-modal cycle. This section describes how to test engines under steady-state conditions. Manufacturers may alternatively use the...

  14. 40 CFR 85.2225 - Steady state test exhaust analysis system-EPA 91.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Steady state test exhaust analysis... Performance Warranty Short Tests § 85.2225 Steady state test exhaust analysis system—EPA 91. (a) Special... for steady state short tests consists, at a minimum, of a tailpipe probe; a flexible sample line; a...

  15. 40 CFR Appendix II to Part 1039 - Steady-State Duty Cycles

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Steady-State Duty Cycles II Appendix... Appendix II to Part 1039—Steady-State Duty Cycles (a) The following duty cycles apply for constant-speed...(seconds) Engine speed Torque(percent) 1, 2 1a Steady-state 53 Engine governed 100. 1b Transition 20 Engine...

  16. 40 CFR 86.1363-2007 - Steady-state testing with a discrete-mode cycle.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 19 2010-07-01 2010-07-01 false Steady-state testing with a discrete... Exhaust Test Procedures § 86.1363-2007 Steady-state testing with a discrete-mode cycle. This section describes an alternate procedure for steady-state testing that manufacturers may use through the 2009 model...

  17. 40 CFR Appendix II to Part 1042 - Steady-State Duty Cycles

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Steady-State Duty Cycles II Appendix..., App. II Appendix II to Part 1042—Steady-State Duty Cycles (a) The following duty cycles apply as... Time in mode(seconds) Engine speed 1, 3 Power (percent) 2, 3 1aSteady-state 229 Maximum test speed 100...

  18. 40 CFR 85.2230 - Steady state test dynamometer-EPA 91.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Steady state test dynamometer-EPA 91... Warranty Short Tests § 85.2230 Steady state test dynamometer—EPA 91. (a) Special calendar and model year... or engines. (b) The chassis dynamometer for steady state short tests must provide the capabilities...

  19. Mass transfer in a salt repository

    International Nuclear Information System (INIS)

    Pigford, T.H.; Chambre, P.L.

    1985-05-01

    To meet regulatory requirements for radioactive waste in a salt repository it is necessary to predict the rates of corrosion of the waste container, the release rates of radionuclides from the waste package, and the cumulative release of radionuclides into the accessible environment. The mechanisms that may control these rates and an approach to predicting these rates from mass-transfer theory are described. This new mechanistic approach is suggested by three premises: (a) a brine inclusion originally in a salt crystal moves along grain boundaries after thermal-induced migration out of the crystal, (b) brine moves along a grain boundary under the influence of a pressure gradient, and (c) salt surrounding a heat-generating waste package will soon creep and consolidate as a monolithic medium surrounding and in contact with the waste package. After consolidation there may be very little migration of intergranular and intragranular brine to the waste package. The corrosion rate of the waste container may then be limited by the rate at which brine reaches the container and may be calculable from mass-transfer theory, and the rate at which dissolved radionuclides leave the waste package may be limited by molecular diffusion in intragranular brine and may be calculable from mass-transfer theory. If porous nonsalt interbeds intersect the waste-package borehole, the release rate of dissolved radionuclides to interbed brine may also be calculable from mass-transfer theory. The logic of these conclusions is described, as an aid in formulating the calculations that are to be made

  20. Steady State Transportation Cooling in Porous Media Under Local, Non-Thermal Equilibrium Fluid Flow

    Science.gov (United States)

    Rodriquez, Alvaro Che

    2002-01-01

    An analytical solution to the steady-state fluid temperature for 1-D (one dimensional) transpiration cooling has been derived. Transpiration cooling has potential use in the aerospace industry for protection against high heating environments for re-entry vehicles. Literature for analytical treatments of transpiration cooling has been largely confined to the assumption of thermal equilibrium between the porous matrix and fluid. In the present analysis, the fundamental fluid and matrix equations are coupled through a volumetric heat transfer coefficient and investigated in non-thermal equilibrium. The effects of varying the thermal conductivity of the solid matrix and the heat transfer coefficient are investigated. The results are also compared to existing experimental data.

  1. Active ideal sedimentation: exact two-dimensional steady states.

    Science.gov (United States)

    Hermann, Sophie; Schmidt, Matthias

    2018-02-28

    We consider an ideal gas of active Brownian particles that undergo self-propelled motion and both translational and rotational diffusion under the influence of gravity. We solve analytically the corresponding Smoluchowski equation in two space dimensions for steady states. The resulting one-body density is given as a series, where each term is a product of an orientation-dependent Mathieu function and a height-dependent exponential. A lower hard wall is implemented as a no-flux boundary condition. Numerical evaluation of the suitably truncated analytical solution shows the formation of two different spatial regimes upon increasing Peclet number. These regimes differ in their mean particle orientation and in their variation of the orientation-averaged density with height.

  2. Analysis of steady-state ductile crack growth

    DEFF Research Database (Denmark)

    Niordson, Christian

    1999-01-01

    The fracture strength under quasi-static steady-state crack growth in an elastic-plastic material joined by a laser weld is analyzed. Laser welding gives high mismatch between the yield stress within the weld and the yield stress in the base material. This is due to the fast termic cycle, which...... the finite element mesh remains fixed relative to the tip of the growing crack. Fracture is modelled using two different local crack growth criteria. One is a crack opening displacement criterion, while the other is a model in which a cohesive zone is imposed in front of the crack tip along the fracture zone....... Both models predict that in general a thinner laser weld gives higher interface strength. Furthermore, both fracture criteria show, that the preferred path of the crack is close outside the weld material; a phenomenon also observed in experiments....

  3. Nuclide Importance and the Steady-State Burnup Equation

    International Nuclear Information System (INIS)

    Sekimoto, Hiroshi; Nemoto, Atsushi

    2000-01-01

    Conventional methods for evaluating some characteristic values of nuclides relating to burnup in a given neutron spectrum are reviewed in a mathematically systematic way, and a new method based on the importance theory is proposed. In this method, these characteristic values of a nuclide are equivalent to the importances of the nuclide. By solving the equation adjoint to the steady-state burnup equation with a properly chosen source term, the importances for all nuclides are obtained simultaneously.The fission number importance, net neutron importance, fission neutron importance, and absorbed neutron importance are evaluated and discussed. The net neutron importance is a measure directly estimating neutron economy, and it can be evaluated simply by calculating the fission neutron importance minus the absorbed neutron importance, where only the absorbed neutron importance depends on the fission product. The fission neutron importance and absorbed neutron importance are analyzed separately, and detailed discussions of the fission product effects are given for the absorbed neutron importance

  4. Fast Prediction Method for Steady-State Heat Convection

    KAUST Repository

    Wáng, Yì

    2012-03-14

    A reduced model by proper orthogonal decomposition (POD) and Galerkin projection methods for steady-state heat convection is established on a nonuniform grid. It was verified by thousands of examples that the results are in good agreement with the results obtained from the finite volume method. This model can also predict the cases where model parameters far exceed the sample scope. Moreover, the calculation time needed by the model is much shorter than that needed for the finite volume method. Thus, the nonuniform POD-Galerkin projection method exhibits high accuracy, good suitability, and fast computation. It has universal significance for accurate and fast prediction. Also, the methodology can be applied to more complex modeling in chemical engineering and technology, such as reaction and turbulence. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Stationary Distribution and Thermodynamic Relation in Nonequilibrium Steady States

    KAUST Repository

    Komatsu, Teruhisa S.

    2010-01-01

    We describe our recent attempts toward statistical mechanics and thermodynamics for nonequilibrium steady states (NESS) realized, e.g., in a heat conducting system. Our first result is a simple expression of the probability distribution (of microscopic states) of a NESS. Our second result is a natural extension of the thermodynamic Clausius relation and a definition of an accompanying entropy in NESS. This entropy coincides with the normalization constant appearing in the above mentioned microscopic expression of NESS, and has an expression similar to the Shannon entropy (with a further symmetrization). The NESS entropy proposed here is a clearly defined measurable quantity even in a system with a large degrees of freedom. We numerically measure the NESS entropy in hardsphere fluid systems with a heat current, by observing energy exchange between the system and the heat baths when the temperatures of the baths are changed according to specified protocols.

  6. An Adsorption Equilibria Model for Steady State Analysis

    KAUST Repository

    Ismail, Azhar Bin

    2016-02-29

    The investigation of adsorption isotherms is a prime factor in the ongoing development of adsorption cycles for a spectrum of advanced, thermally-driven engineering applications, including refrigeration, natural gas storage, and desalination processes. In this work, a novel semi-empirical mathematical model has been derived that significantly enhances the prediction of the steady state uptake in adsorbent surfaces. This model, a combination of classical Langmuir and a novel modern adsorption isotherm equation, allows for a higher degree of regression of both energetically homogenous and heterogeneous adsorbent surfaces compared to several isolated classical and modern isotherm models, and has the ability to regress isotherms for all six types under the IUPAC classification. Using a unified thermodynamic framework, a single asymmetrical energy distribution function (EDF) has also been proposed that directly relates the mathematical model to the adsorption isotherm types. This fits well with the statistical rate theory approach and offers mechanistic insights into adsorption isotherms.

  7. BR2 reactor core steady state transient modeling

    International Nuclear Information System (INIS)

    Makarenko, A.; Petrova, T.

    2000-01-01

    A coupled neutronics/hydraulics/heat-conduction model of the BR2 reactor core is under development at SCK-CEN. The neutron transport phenomenon has been implemented as steady state and time dependent nodal diffusion. The non-linear heat conduction equation in-side fuel elements is solved with a time dependent finite element method. To allow coupling between functional modules and to simulate subcooled regimes, a simple single-phase hydraulics has been introduced, while the two-phase hydraulics is under development. Multiple tests, general benchmark cases as well as calculation/experiment comparisons demonstrated a good accuracy of both neutronic and thermal hydraulic models, numerical reliability and full code portability. A refinement methodology has been developed and tested for better neutronic representation in hexagonal geometry. Much effort is still needed to complete the development of an extended cross section library with kinetic data and two-phase flow representation. (author)

  8. Exploiting the steady state, continuous fueling reactor model

    International Nuclear Information System (INIS)

    Vondy, D.R.; Cunningham, G.W.; Fowler, T.B.

    1979-01-01

    A continuously fueled reactor presents an analysis challenge, especially so when the neutron accounting is sensitive to the core design and the fuel handling. A scheme was implemented to solve the steady state, continuous fueling problem. This problem is an accurate model of the reactor for assessing performance at a point in its operating history. Available capability in a modular code system developed to treat fixed fuel reactors was extended in this effort. Parametric studies have been made with this capability to assess the performance of a pebble bed power plant reactor over a wide range of fueling possibilities. The model and the calculational methods are discussed. A global iteration scheme is used to effect a solution for the critical reactor state. The schemes used to accelerate the rate of convergence of one- and two-dimensional problems are described and the interactive behavior is shown for representative problems

  9. Creep stresses in a spherical shell under steady state temperature

    Science.gov (United States)

    Verma, Gaurav; Rana, Puneet

    2017-10-01

    The paper investigates the problem of creep of a spherical structure under the influence of steady state temperature. The problem of creep in spherical shell is solved by using the concept of generalized strain measures and transition hypothesis given by Seth. The problem has reduced to non-linear differential equation for creep transition. This paper deals with the non-linear behaviour of spherical shell under thermal condition. The spherical shell structures are easily vulnerable to creep, shrinkage and thermal effects; a thorough understanding of their time-dependent behaviour has been fully established. The paper aims to provide thermal creep analysis to enhance the effective design and long life of shells, and a theoretical model is developed for calculating creep stresses and strains in a spherical shell with purpose. Results obtained for the problem are depicted graphically.

  10. Steady State Temperature Profile in a Cylinder Heated by Microwaves

    Science.gov (United States)

    Jackson, H. W.; Barmatz, M.; Wagner, P.

    1995-01-01

    A new theory has been developed to calculate the steady state temperature profile in a cylindrical sample positioned along the entire axis of a cylindrical microwave cavity. Temperature profiles where computed for- alumina rods of various radii contained in a cavity excite in one of the TM(sub OnO) modes with n = 1, 2 or 3. Calculations where also performed with a concentric outer cylindrical tube surrounding the rod to investigate hybrid heating. The parameters studies of the sample center and surface temperature where performed as a function of the total power transmitted into the cavity. Also, the total hemispherical emissivity was varied at boundaries of the rod, surrounding tube, and cavity walls. The result are discussed in the context of controlling the average rod temperature and the temperature distribution in the rod during microwave processing.

  11. NASA Lewis Steady-State Heat Pipe Code Architecture

    Science.gov (United States)

    Mi, Ye; Tower, Leonard K.

    2013-01-01

    NASA Glenn Research Center (GRC) has developed the LERCHP code. The PC-based LERCHP code can be used to predict the steady-state performance of heat pipes, including the determination of operating temperature and operating limits which might be encountered under specified conditions. The code contains a vapor flow algorithm which incorporates vapor compressibility and axially varying heat input. For the liquid flow in the wick, Darcy s formula is employed. Thermal boundary conditions and geometric structures can be defined through an interactive input interface. A variety of fluid and material options as well as user defined options can be chosen for the working fluid, wick, and pipe materials. This report documents the current effort at GRC to update the LERCHP code for operating in a Microsoft Windows (Microsoft Corporation) environment. A detailed analysis of the model is presented. The programming architecture for the numerical calculations is explained and flowcharts of the key subroutines are given

  12. Period doubling in period-one steady states

    Science.gov (United States)

    Wang, Reuben R. W.; Xing, Bo; Carlo, Gabriel G.; Poletti, Dario

    2018-02-01

    Nonlinear classical dissipative systems present a rich phenomenology in their "route to chaos," including period doubling, i.e., the system evolves with a period which is twice that of the driving. However, typically the attractor of a periodically driven quantum open system evolves with a period which exactly matches that of the driving. Here, we analyze a periodically driven many-body open quantum system whose classical correspondent presents period doubling. We show that by studying the dynamical correlations, it is possible to show the occurrence of period doubling in the quantum (period-one) steady state. We also discuss that such systems are natural candidates for clean and intrinsically robust Floquet time crystals.

  13. Quasi-steady-state regime in transient stimulated Raman scattering

    International Nuclear Information System (INIS)

    Ackerhalt, J.R.; Kurnit, N.A.

    1987-01-01

    A method is developed for studying transient stimulated Raman scattering in the quasi-steady-state regime when the input pump field consists of a repetitive periodic sequence of pulses. The method is most attractive for cases where the single-pulse duration is substantially shorter than the repetition time scale, making a straightforward numerical simulation very costly, time consuming, and potentially intractable. The method is applicable to any periodic electric field envelope including that generated by a finite number of longitudinal modes with arbitrary phase. A second numerically efficient method is developed for treating the buildup of the entire pulse train. In addition, an analytic solution is found in the undepleted-pump regime which illuminates the underlying physics of the process

  14. Modular first wall concept for steady state operation

    International Nuclear Information System (INIS)

    Kotzlowski, H.E.

    1981-01-01

    On the basis of the limiter design proposed for ZEPHYR a first wall concept has been developed which can also be used as a large area limiter, heat shield or beam pump. Its specific feature is the thermal contact of the wall armour elements with the water-cooled base plates. The combination of radiation and contact cooling, compared with radiation only, helps to lower the steady state temperatures of the first wall by approximately 50 % and to reduce the cooling-time between discharges. Particulary the lower wall temperature give a larger margin for additional heating of the wall by plasma disruption or neutral beams until excessive erosion or damage of the armour takes place

  15. Steady-State Density Functional Theory for Finite Bias Conductances.

    Science.gov (United States)

    Stefanucci, G; Kurth, S

    2015-12-09

    In the framework of density functional theory, a formalism to describe electronic transport in the steady state is proposed which uses the density on the junction and the steady current as basic variables. We prove that, in a finite window around zero bias, there is a one-to-one map between the basic variables and both local potential on as well as bias across the junction. The resulting Kohn-Sham system features two exchange-correlation (xc) potentials, a local xc potential, and an xc contribution to the bias. For weakly coupled junctions the xc potentials exhibit steps in the density-current plane which are shown to be crucial to describe the Coulomb blockade diamonds. At small currents these steps emerge as the equilibrium xc discontinuity bifurcates. The formalism is applied to a model benzene junction, finding perfect agreement with the orthodox theory of Coulomb blockade.

  16. Plasticity, Fracture and Friction in Steady-State Plate Cutting

    DEFF Research Database (Denmark)

    Simonsen, Bo Cerup; Wierzbicki, Tomasz

    1997-01-01

    A closed form solution to the problem of steady-state wedge cutting through a ductile metal plate is presented. The considered problem is an idealization of a ship bottom raking process, i.e. a continuous cutting damage of a ship bottom by a hard knife-like rock in a grounding event. A new...... extension of the presented plate model to include more structural members as for example the stiffeners attached to a ship bottom plating. The fracture process is discussed and the model is formulated partly on the basis of the material fracture toughness. The effect of friction and the reaction force...... perpendicular to the direction of motion is derived theoretically in a consistent manner. The perpendicular reaction force is of paramount importance for prediction the structural damage of a ship hull because it governs the vertical ship motion and rock penetration which is strongly coupled with the horizontal...

  17. Three dimensional modeling on airflow, heat and mass transfer in partially impermeable enclosure containing agricultural produce during natural convective cooling

    International Nuclear Information System (INIS)

    Chourasia, M.K.; Goswami, T.K.

    2007-01-01

    A three dimensional model was developed to simulate the transport phenomena in heat and mass generating porous medium cooled under natural convective environment. Unlike the previous works on this aspect, the present model was aimed for bulk stored agricultural produce contained in a permeable package placed on a hard surface. This situation made the bottom of the package impermeable to fluid flow as well as moisture transfer and adiabatic to heat transfer. The velocity vectors, isotherms and contours of rate of moisture loss were presented during transient cooling as well as at steady state using the commercially available computational fluid dynamics (CFD) code based on the finite volume technique. The CFD model was validated using the experimental data on the time-temperature history as well as weight loss obtained from a bag of potatoes kept in a cold store. The simulated and experimental values on temperature and moisture loss of the product were found to be in good agreement

  18. Data acquisition system for steady state experiments at multi-sites

    International Nuclear Information System (INIS)

    Nakanishi, H.; Emoto, M.; Nagayama, Y.

    2010-11-01

    A high-performance data acquisition system (LABCOM system) has been developed for steady state fusion experiments in Large Helical Device (LHD). The most important characteristics of this system are the 110 MB/s high-speed real-time data acquisition capability and also the scalability on its performance by using unlimited number of data acquisition (DAQ) units. It can also acquire experimental data from multiple remote sites through the 1 Gbps fusion-dedicated virtual private network (SNET) in Japan. In LHD steady-state experiments, the DAQ cluster has established the world record of acquired data amount of 90 GB/shot which almost reaches the ITER data estimate. Since all the DAQ, storage, and data clients of LABCOM system are distributed on the local area network (LAN), remote experimental data can be also acquired simply by extending the LAN to the wide-area SNET. The speed lowering problem in long-distance TCP/IP data transfer has been improved by using an optimized congestion control and packet pacing method. Japan-France and Japan-US network bandwidth tests have revealed that this method actually utilize 90% of ideal throughput in both cases. Toward the fusion goal, a common data access platform is indispensable so that detailed physics data can be easily compared between multiple large and small experiments. The demonstrated bilateral collaboration scheme will be analogous to that of ITER and the supporting machines. (author)

  19. Theoretical studies on membrane-based gas separation using computational fluid dynamics (CFD) of mass transfer

    International Nuclear Information System (INIS)

    Sohrabi, M.R.; Marjani, A.; Davallo, M.; Moradi, S.; Shirazian, S.

    2011-01-01

    A 2D mass transfer model was developed to study carbon dioxide removal by absorption in membrane contactors. The model predicts the steady state absorbent and carbon dioxide concentrations in the membrane by solving the conservation equations. The continuity equations for three sub domains of the membrane contactor involving the tube; membrane and shell were obtained and solved by finite element method (FEM). The model was based on 'non-wetted mode' in which the gas phase filled the membrane pores. Laminar parabolic velocity profile was used for the liquid flow in the tube side; whereas, the gas flow in the shell side was characterized by Happel's free surface model. Axial and radial diffusion transport inside the shell, through the membrane, and within the tube side of the contactor was considered in the mass transfer model. The predictions of percent CO/sub 2/ removal obtained by modeling were compared with the experimental values obtained from literature. They were the experimental results for CO/sub 2/ removal from CO/sub 2//N/sub 2/ gas mixture with amines aqueous solutions as the liquid solvent using polypropylene membrane contactor. The modeling predictions were in good agreement with the experimental values for different values of gas and liquid flow rates. (author)

  20. A comparative study of the mass and heat transfer dynamics of evaporating ethanol/water, methanol/water, and 1-propanol/water aerosol droplets.

    Science.gov (United States)

    Hopkins, Rebecca J; Reid, Jonathan P

    2006-02-23

    The mass and heat transfer dynamics of evaporating multicomponent alcohol/water droplets have been probed experimentally by examining changes in the near surface droplet composition and average droplet temperature using cavity-enhanced Raman scattering (CERS) and laser-induced fluorescence (LIF). The CERS technique provides a sensitive measure of the concentration of the volatile alcohol component in the outer shell of the droplet, due to the exponential relationship between CERS intensity and species concentration. Such volatile droplets, which are probed on a millisecond time scale, evaporate nonisothermally, resulting in both temperature and concentration gradients, as confirmed by comparisons between experimental measurements and quasi-steady state model calculations. An excellent agreement between the experimental evaporation trends and quasi-steady state model predictions is observed. An unexpectedly slow evaporation rate is observed for the evaporation of 1-propanol from a multicomponent droplet when compared to the model; possible explanations for this observation are discussed. In addition, the propagation depth of the CERS signal, and, therefore, the region of the droplet from which compositional measurements are made, can be estimated. Such measurements, when considered in conjunction with quasi-steady state theory, can allow droplet temperature gradients to be measured and vapor pressures and activity coefficients of components within the droplet to be determined.

  1. Weathering rates and steady-state critical loads for forest soils in the Georgia Basin

    Energy Technology Data Exchange (ETDEWEB)

    Mongeon, A.; Aherne, J.; Watmough, S. [Trent Univ., Peterborough, ON (Canada). Watershed Science Centre

    2007-07-01

    Sulphur and nitrogen emissions in the Georgia Basin resulting from expansions in urban and industrial development are now leading to the acidification of soils in the region. This study used weathering rates to evaluate the sensitivity of soils and to determine weathering rates for rooting zones at 19 sites within the Georgia Basin. Soils with low weathering rates are sensitive to acid deposition. A process-oriented soil chemical weathering model was used to calculate weathering rates for each study site as well as to determine steady-state critical loads for acid deposition. Soils at the sites were mainly podzols or brunisols, with forests composed of Douglas Fir, Western Hemlock, Western Red Cedar, Amablis Fir, Sitka Spruce, and Paper Birch. Sites ranged in elevation between 100 m to 1370 m. A steady-state simple mass balance model (SSMB) was used to estimate critical loads. The sites exhibited a large range in estimated weathering rates. Sixteen sites had weathering rates lower than 1.50 keq/ha/yr. Estimated critical loads also exhibited a large range of values. It was concluded that sulphur and nitrogen deposition at various sites with low weathering rates exceeded estimated critical loads. Further acidification studies in various regions were recommended. 30 refs., 3 tabs., 1 fig.

  2. Steady state and dynamic modelling for a hybrid approach to post combustion capture

    Energy Technology Data Exchange (ETDEWEB)

    Stephenson, P.; Tian, J. [RWE npower (United Kingdom); Jovanovich, S.; Tian, X. [BOC Linde, Munich (Germany)

    2009-07-01

    This poster presentation illustrated a hybrid method for carbon-capture, which includes features of both oxyfuel and post-combustion capture. The method was developed jointly by BOC Linde and RWE npower as part of the ECO-COPPS project funded by the UK Government. The method involves the use of an air separation unit (ASU) to enrich the oxygen level in the gas entering the furnace. This increases the CO{sub 2} concentration in the flue gas and decreases the flue gas mass flow rate. The method should therefore require a smaller ASU than oxyfuel and a smaller post-combustion capture plant than with air-firing. The objective is to lower costs. The project involves both steady-state and dynamic modelling of the overall process. Although Doosan Babcock and the University of Leeds are also involved in the modelling aspects of the project, this presentation focused only on the modelling conducted by RWE and BOC of various aspects of the process, such as ASUs or the furnace/steam cycle or the post-combustion capture, using codes such as HYSYS or PROMAX or gPROMS. A simple steady state model was developed to determine if the ECO-COPPS hybrid idea is worth pursuing. RWE and BOC have also examined the potential requirements for dynamic response and the plant issues that may pose a challenge in meeting these requirements. RWE is in the process of developing simple dynamic models to simulate plant flexibility and effects of load changes.

  3. Steady-state thermodynamic simulation and structural design of the dephlegmator used in mixed-refrigerant Joule-Thomson refrigerators

    International Nuclear Information System (INIS)

    Li, Mei; Gong, Maoqiong; Guo, Hao; Sun, Zhaohu; Wu, Jianfeng

    2016-01-01

    Highlights: • Good agreements and the feasibility of the MESH model were found. • Fine applicability and low energy consumption of the dephlegmator were addressed. • A clear and comprehensive three-dimensional dephlegmator model was shown. - Abstract: Dephlegmators can be used to reduce the energy consumption and simplify the layout of the mixed-refrigerant Joule–Thomson (MRJT) cycle. Heat-exchange characteristics and refrigeration design are currently based on highly simplified assumptions. Synthesis methods to efficiently solve all design issues of dephlegmators in MRJT cycle are insufficient. No suitable separation module is available for the simultaneous heat and mass transfer processes in Aspen Plus because the module should be programmed and incorporated into Aspen Plus as a user-defined unit. In this paper, a systematic steady-state method was proposed for the detailed design of dephlegmators for gas mixture separation, considering the simulation and heat exchanger design simultaneously. The material balance, vapor–liquid equilibrium, mole fraction summation and heat balance (MESH) model was programmed in FORTRAN language. Good agreements and the feasibility of the MESH model were found. Deviations between the simulation results and patent data were all within 5%. The errors in the predicted temperatures of vapor and liquid products were less than 2% and 10%, respectively. Fine applicability and low energy consumption of the dephlegmator were addressed. The mole fraction of n-butane in the liquid phase had high recovery ratio of 90%. The dephlegmator decreased more than 30% of energy consumption compared with the traditional distillation tower under similar separation effects. In the structural design process, the dephlegmator was divided into certain segments by baffle plates on the basis of segmented calculation. The heat transfer coefficient, heat transfer area, pressure drop, and structural parameters of the dephlegmator were evaluated. A clear

  4. Mixing and Mass Transfer in Industrial Bioreactors

    DEFF Research Database (Denmark)

    Villadsen, John

    2015-01-01

    Design of a real reactor for a real process in industrial scale requires much more than the design of the "ideal" reactors. This insight is formulated in empirical relations between key process parameters, such as mass and heat transfer coefficients, and the power input to the process. Mixing...... formulas are not in any way quantitatively correct, but based on dimensional analysis one is able to extrapolate from small-to large-scale operation. It is shown that linear scale-up may not give the smallest power input for a given mixing objective. The introduction presented is the basis...... for the visionary scale-up/scale-down design principles....

  5. Mass transfer in gas-liquid slurry reactors

    NARCIS (Netherlands)

    Beenackers, A.A.C.M.; van Swaaij, Willibrordus Petrus Maria

    1993-01-01

    A critical review is presented on the mass transfer characteristics of gas¿liquid slurry reactors. The recent findings on the influence of the presence of solid particles on the following mass transfer parameters in slurry reactors are discussed: volumetric gas¿liquid mass transfer coefficients

  6. Numerical simulation of steady-state and transient natural convection in an isothermal open cubic cavity

    Energy Technology Data Exchange (ETDEWEB)

    Hinojosa, J.F. [Universidad de Sonora, Departamento de Ingenieria Quimica y Metalurgia, Hermosillo, Sonora (Mexico); Cervantes-de Gortari, J. [Universidad Nacional Autonoma de Mexico, Departamento de Termofluidos, Facultad de Ingenieria, Mexico, D.F. (Mexico)

    2010-06-15

    In this work the numeric results, of the steady-state and transient heat transfer by natural convection in a horizontal isothermal open cubic cavity are presented. The most important assumptions in the mathematical formulation are two, the flow is laminar and the Boussinesq approximation is valid. The conservation equations in primitive variables are solved using the finite volume method and the SIMPLEC algorithm. The advective terms are approximated by the SMART scheme and the diffusive terms are approximated using the central differencing scheme. The results are obtained for a Rayleigh number range from 10{sup 4} to 10{sup 7}.The numerical model predicted flow instabilities and Nusselt number oscillations for high Rayleigh numbers. (orig.)

  7. A theory of nonequilibrium steady states in quantum chaotic systems

    Science.gov (United States)

    Wang, Pei

    2017-09-01

    Nonequilibrium steady state (NESS) is a quasistationary state, in which exist currents that continuously produce entropy, but the local observables are stationary everywhere. We propose a theory of NESS under the framework of quantum chaos. In an isolated quantum system whose density matrix follows a unitary evolution, there exist initial states for which the thermodynamic limit and the long-time limit are noncommutative. The density matrix \\hat ρ of these states displays a universal structure. Suppose that \\renewcommand{\\ket}[1]{{\\vert #1 >}} \\ketα and \\renewcommand{\\ket}[1]{{\\vert #1 >}} \\ketβ are different eigenstates of the Hamiltonian with energies E_α and E_β , respectively. \\renewcommand{\\bra}[1]{} \\braα\\hat ρ \\ketβ behaves as a random number which has zero mean. In thermodynamic limit, the variance of \\renewcommand{\\bra}[1]{} \\braα\\hat ρ \\ketβ is a smooth function of ≤ft\\vert E_α-E_β\\right\\vert , scaling as 1/≤ft\\vert E_α-E_β\\right\\vert 2 in the limit ≤ft\\vert E_α-E_β\\right\\vert \\to 0 . If and only if this scaling law is obeyed, the initial state evolves into NESS in the long time limit. We present numerical evidence of our hypothesis in a few chaotic models. Furthermore, we find that our hypothesis indicates the eigenstate thermalization hypothesis (ETH) for current operators in a bipartite system.

  8. Steady State Analysis of Small Molten Salt Reactor

    Science.gov (United States)

    Yamamoto, Takahisa; Mitachi, Koshi; Suzuki, Takashi

    The Molten Salt Reactor (MSR) is a thermal neutron reactor with graphite moderation and operates on the thorium-uranium fuel cycle. The feature of the MSR is that fuel salt flows inside the reactor during the nuclear fission reaction. In the previous study, the authors developed numerical model with which to simulate the effects of fuel salt flow on the reactor characteristics. In this study, we apply the model to the steady-state analysis of a small MSR system and estimate the effects of fuel flow. The model consists of two-group neutron diffusion equations for fast and thermal neutron fluxes, transport equations for six-group delayed neutron precursors and energy conservation equations for fuel salt and the graphite moderator. The following results are obtained: (1) in the rated operation condition, the peaks of the neutron fluxes slightly move toward the bottom from the center of the reactor and the delayed neutron precursors are significantly carried by the fuel salt flow, and (2) the extension of residence time in the external-loop system and the rise of the fuel inflow temperature show weak negative reactivity effects, which decrease the neutron multiplication factor of the small MSR system.

  9. Ising game: Nonequilibrium steady states of resource-allocation systems

    Science.gov (United States)

    Xin, C.; Yang, G.; Huang, J. P.

    2017-04-01

    Resource-allocation systems are ubiquitous in the human society. But how external fields affect the state of such systems remains poorly explored due to the lack of a suitable model. Because the behavior of spins pursuing energy minimization required by physical laws is similar to that of humans chasing payoff maximization studied in game theory, here we combine the Ising model with the market-directed resource-allocation game, yielding an Ising game. Based on the Ising game, we show theoretical, simulative and experimental evidences for a formula, which offers a clear expression of nonequilibrium steady states (NESSs). Interestingly, the formula also reveals a convertible relationship between the external field (exogenous factor) and resource ratio (endogenous factor), and a class of saturation as the external field exceeds certain limits. This work suggests that the Ising game could be a suitable model for studying external-field effects on resource-allocation systems, and it could provide guidance both for seeking more relations between NESSs and equilibrium states and for regulating human systems by choosing NESSs appropriately.

  10. Visual steady state in relation to age and cognitive function.

    Directory of Open Access Journals (Sweden)

    Anna Horwitz

    Full Text Available Neocortical gamma activity is crucial for sensory perception and cognition. This study examines the value of using non-task stimulation-induced EEG oscillations to predict cognitive status in a birth cohort of healthy Danish males (Metropolit with varying cognitive ability. In particular, we examine the steady-state VEP power response (SSVEP-PR in the alpha (8Hz and gamma (36Hz bands in 54 males (avg. age: 62.0 years and compare these with 10 young healthy participants (avg. age 27.6 years. Furthermore, we correlate the individual alpha-to-gamma difference in relative visual-area power (ΔRV with cognitive scores for the older adults. We find that ΔRV decrease with age by just over one standard deviation when comparing young with old participants (p<0.01. Furthermore, intelligence is significantly negatively correlated with ΔRV in the older adult cohort, even when processing speed, global cognition, executive function, memory, and education (p<0.05. In our preferred specification, an increase in ΔRV of one standard deviation is associated with a reduction in intelligence of 48% of a standard deviation (p<0.01. Finally, we conclude that the difference in cerebral rhythmic activity between the alpha and gamma bands is associated with age and cognitive status, and that ΔRV therefore provide a non-subjective clinical tool with which to examine cognitive status in old age.

  11. Steady-state growth of the marine diatom Thalassiosira pseudonana

    International Nuclear Information System (INIS)

    Olson, R.J.; SooHoo, J.B.; Kiefer, D.A.

    1980-01-01

    Seasonal studies of the vertical distribution of nitrate, nitrite, and phytoplankton in the oceans and studies using 15 N as a tracer of nitrate metabolism indicate that the reduction of nitrate by phytoplankton is a source of nitrite in the upper waters of the ocean. To better understand this process, the relationship between nitrate uptake and nitrite production has been examined with continuous cultures of the small marine diatom Thalassiosira pseudonana. In a turbidostat culture, the rates of nitrite production by T. Pseudonana increase with light intensity. This process is only loosely coupled to rates of nitrate assimilation since the ratio of net nitrite production to total nitrate assimilation increases with increased rates of growth. In continuous cultures where steady-state concentrations of nitrate and nitrite were varied, T. pseudonana produced nitrite at rates which increased with increasing concentrations of nitrate. Again, the rates of nitrite production were uncoupled from rates of nitrate assimilation. The study was used to derive a mathematical description of nitrate and nitrite metabolism by T. pseudonana. The validity of this model was supported by the results of a study in which 15 N-labeled nitrite was introduced into the continuous culture, and the model was used to examine patterns in distribution of nitrite in the Antarctic Ocean and the Sargasso Sea

  12. Electrically evoked auditory steady-state responses in Guinea pigs.

    Science.gov (United States)

    Jeng, Fuh-Cherng; Abbas, Paul J; Brown, Carolyn J; Miller, Charles A; Nourski, Kirill V; Robinson, Barbara K

    2007-01-01

    Most cochlear implant systems available today provide the user with information about the envelope of the speech signal. The goal of this study was to explore the feasibility of recording electrically evoked auditory steady-state response (ESSR) and in particular to evaluate the degree to which the response recorded using electrical stimulation could be separated from stimulus artifact. Sinusoidally amplitude-modulated electrical stimuli with alternating polarities were used to elicit the response in adult guinea pigs. Separation of the stimulus artifact from evoked neural responses was achieved by summing alternating polarity responses or by using spectral analysis techniques. The recorded response exhibited physiological response properties including a pattern of nonlinear growth and their abolishment following euthanasia or administration of tetrodotoxin. These findings demonstrate that the ESSR is a response generated by the auditory system and can be separated from electrical stimulus artifact. As it is evoked by a stimulus that shares important features of cochlear implant stimulation, this evoked potential may be useful in either clinical or basic research efforts. Copyright 2007 S. Karger AG, Basel.

  13. Attentional Modulation of Auditory Steady-State Responses

    Science.gov (United States)

    Mahajan, Yatin; Davis, Chris; Kim, Jeesun

    2014-01-01

    Auditory selective attention enables task-relevant auditory events to be enhanced and irrelevant ones suppressed. In the present study we used a frequency tagging paradigm to investigate the effects of attention on auditory steady state responses (ASSR). The ASSR was elicited by simultaneously presenting two different streams of white noise, amplitude modulated at either 16 and 23.5 Hz or 32.5 and 40 Hz. The two different frequencies were presented to each ear and participants were instructed to selectively attend to one ear or the other (confirmed by behavioral evidence). The results revealed that modulation of ASSR by selective attention depended on the modulation frequencies used and whether the activation was contralateral or ipsilateral. Attention enhanced the ASSR for contralateral activation from either ear for 16 Hz and suppressed the ASSR for ipsilateral activation for 16 Hz and 23.5 Hz. For modulation frequencies of 32.5 or 40 Hz attention did not affect the ASSR. We propose that the pattern of enhancement and inhibition may be due to binaural suppressive effects on ipsilateral stimulation and the dominance of contralateral hemisphere during dichotic listening. In addition to the influence of cortical processing asymmetries, these results may also reflect a bias towards inhibitory ipsilateral and excitatory contralateral activation present at the level of inferior colliculus. That the effect of attention was clearest for the lower modulation frequencies suggests that such effects are likely mediated by cortical brain structures or by those in close proximity to cortex. PMID:25334021

  14. Attentional modulation of auditory steady-state responses.

    Directory of Open Access Journals (Sweden)

    Yatin Mahajan

    Full Text Available Auditory selective attention enables task-relevant auditory events to be enhanced and irrelevant ones suppressed. In the present study we used a frequency tagging paradigm to investigate the effects of attention on auditory steady state responses (ASSR. The ASSR was elicited by simultaneously presenting two different streams of white noise, amplitude modulated at either 16 and 23.5 Hz or 32.5 and 40 Hz. The two different frequencies were presented to each ear and participants were instructed to selectively attend to one ear or the other (confirmed by behavioral evidence. The results revealed that modulation of ASSR by selective attention depended on the modulation frequencies used and whether the activation was contralateral or ipsilateral. Attention enhanced the ASSR for contralateral activation from either ear for 16 Hz and suppressed the ASSR for ipsilateral activation for 16 Hz and 23.5 Hz. For modulation frequencies of 32.5 or 40 Hz attention did not affect the ASSR. We propose that the pattern of enhancement and inhibition may be due to binaural suppressive effects on ipsilateral stimulation and the dominance of contralateral hemisphere during dichotic listening. In addition to the influence of cortical processing asymmetries, these results may also reflect a bias towards inhibitory ipsilateral and excitatory contralateral activation present at the level of inferior colliculus. That the effect of attention was clearest for the lower modulation frequencies suggests that such effects are likely mediated by cortical brain structures or by those in close proximity to cortex.

  15. Reactor potential of steady-state field-reversed configurations

    International Nuclear Information System (INIS)

    Kernbichler, W.

    1990-01-01

    The intrinsic potential of a Field-Reversed Configuration (FRC) for high-β operation - with β-values in the range of 50 to 100% - stimulates much interest in this device as an attractive candidate for a compact fusion device with high power density. Several additional benefits, e.g. the cylindrical geometry of the concept, the divertor action of the open field lines and the possibility for direct energy conversion of the charged particle flow, justify a closer look at the benefits and problems of FRCs. Present emphasis is on operation with D- 3 He fuel under reactor relevant conditions, whereas D-T is taken as a reference case. A steady-state version of an FRC is considered to be more attractive than its pulsed counterpart. Frequent start-up to high temperatures would be particularly detrimental for D- 3 He where start-up scenarios seem to rely on the transition from D-T to D- 3 He, with unavoidable strong tritium contamination

  16. Prediction of steady state thermohydraulic conditions in water reactor systems

    International Nuclear Information System (INIS)

    Srikantiah, G.

    1975-08-01

    A method developed for the automatic prediction of the initial steady state conditions in reactor systems and a computer code based on this method are described. The reactor system is considered as a hydraulic network made up of the system components and their interconnections. Generalized network methods based on Graph Theory are applied to establish a set of independent equations in terms of the driving potentials and fluxes of the network. The terminal equations relating the ''across'' and ''through'' variables in the system components are derived by applying the one-dimensional drift-flux model. The resulting equations are solved by an appropriate numerical technique. Sample problems have been worked out to illustrate the advantages and the efficiency of this method. The basic advantages are: the component modeling is independent of the method of deriving the final balance equations for the system; the formulation procedure is independent of the numerical technique applied to solve the resulting set of equations, and the entire problem formulation and solution procedure requires a small amount of computer time

  17. Avoiding electromagnetic artifacts when recording auditory steady-state responses.

    Science.gov (United States)

    Picton, Terence W; John, M Sasha

    2004-09-01

    Electromagnetic artifacts can occur when recording multiple auditory steady-state responses evoked by sinusoidally amplitude modulated (SAM) stimuli. High-intensity air-conducted stimuli evoked responses even when hearing was prevented by masking. Additionally, high-intensity bone-conducted stimuli evoked responses that were completely different from those evoked by air-conducted stimuli of similar sensory level. These artifacts were caused by aliasing since they did not occur when recordings used high analog-digital (AD) conversion rates or when high frequencies in the electroencephalographic (EEG) signal were attenuated by steep-slope low-pass filtering. Two possible techniques can displace aliased energy away from the response frequencies: (1) using an AD rate that is not an integer submultiple of the carrier frequencies and (2) using stimuli with frequency spectra that do not alias back to the response frequencies, such as beats or "alternating SAM" tones. Alternating SAM tones evoke responses similar to conventional SAM tones, whereas beats produce significantly smaller responses.

  18. Steady State Turbulent Transport in Magnetic Fusion Plasmas

    International Nuclear Information System (INIS)

    Lee, W.W.; Ethier, S.; Kolesnikov, R.; Wang, W.X.; Tang, W.M.

    2007-01-01

    For more than a decade, the study of microturbulence, driven by ion temperature gradient (ITG) drift instabilities in tokamak devices, has been an active area of research in magnetic fusion science for both experimentalists and theorists alike. One of the important impetus for this avenue of research was the discovery of the radial streamers associated the ITG modes in the early nineties using a Particle-In-Cell (PIC) code. Since then, ITG simulations based on the codes with increasing realism have become possible with the dramatic increase in computing power. The notable examples were the demonstration of the importance of nonlinearly generated zonal flows in regulating ion thermal transport and the transition from Bohm to GyroBoham scaling with increased device size. In this paper, we will describe another interesting nonlinear physical process associated with the parallel acceleration of the ions, that is found to play an important role for the steady state turbulent transport. Its discovery is again through the use of the modern massively parallel supercomputers

  19. Lack of linear correlation between dynamic and steady-state cerebral autoregulation.

    Science.gov (United States)

    de Jong, Daan L K; Tarumi, Takashi; Liu, Jie; Zhang, Rong; Claassen, Jurgen A H R

    2017-08-15

    For correct application and interpretation of cerebral autoregulation (CA) measurements in research and in clinical care, it is essential to understand differences and similarities between dynamic and steady-state CA. The present study found no correlation between dynamic and steady-state CA indices in healthy older adults. There was variability between individuals in all (steady-state and dynamic) autoregulatory indices, ranging from low (almost absent) to highly efficient CA in this healthy population. These findings challenge the assumption that assessment of a single CA parameter or a single set of parameters can be generalized to overall CA functioning. Therefore, depending on specific research purposes, the choice for either steady-state or dynamic measures or both should be weighed carefully. The present study aimed to investigate the relationship between dynamic (dCA) and steady-state cerebral autoregulation (sCA). In 28 healthy older adults, sCA was quantified by a linear regression slope of proportionate (%) changes in cerebrovascular resistance (CVR) in response to proportionate (%) changes in mean blood pressure (BP) induced by stepwise sodium nitroprusside (SNP) and phenylephrine (PhE) infusion. Cerebral blood flow (CBF) was measured at the internal carotid artery (ICA) and vertebral artery (VA) and CBF velocity at the middle cerebral artery (MCA). With CVR = BP/CBF, Slope-CVR ICA , Slope-CVR VA and Slope-CVRi MCA were derived. dCA was assessed (i) in supine rest, analysed with transfer function analysis (gain and phase) and autoregulatory index (ARI) fit from spontaneous oscillations (ARI Baseline ), and (ii) with transient changes in BP using a bolus injection of SNP (ARI SNP ) and PhE (ARI PhE ). Comparison of sCA and dCA parameters (using Pearson's r for continuous and Spearman's ρ for ordinal parameters) demonstrated a lack of linear correlations between sCA and dCA measures. However, comparisons of parameters within dCA and within sCA were

  20. Experimental validation of a thermodynamic boiler model under steady state and dynamic conditions

    International Nuclear Information System (INIS)

    Carlon, Elisa; Verma, Vijay Kumar; Schwarz, Markus; Golicza, Laszlo; Prada, Alessandro; Baratieri, Marco; Haslinger, Walter; Schmidl, Christoph

    2015-01-01

    Highlights: • Laboratory tests on two commercially available pellet boilers. • Steady state and a dynamic load cycle tests. • Pellet boiler model calibration based on data registered in stationary operation. • Boiler model validation with reference to both stationary and dynamic operation. • Validated model suitable for coupled simulation of building and heating system. - Abstract: Nowadays dynamic building simulation is an essential tool for the design of heating systems for residential buildings. The simulation of buildings heated by biomass systems, first of all needs detailed boiler models, capable of simulating the boiler both as a stand-alone appliance and as a system component. This paper presents the calibration and validation of a boiler model by means of laboratory tests. The chosen model, i.e. TRNSYS “Type 869”, has been validated for two commercially available pellet boilers of 6 and 12 kW nominal capacities. Two test methods have been applied: the first is a steady state test at nominal load and the second is a load cycle test including stationary operation at different loads as well as transient operation. The load cycle test is representative of the boiler operation in the field and characterises the boiler’s stationary and dynamic behaviour. The model had been calibrated based on laboratory data registered during stationary operation at different loads and afterwards it was validated by simulating both the stationary and the dynamic tests. Selected parameters for the validation were the heat transfer rates to water and the water temperature profiles inside the boiler and at the boiler outlet. Modelling results showed better agreement with experimental data during stationary operation rather than during dynamic operation. Heat transfer rates to water were predicted with a maximum deviation of 10% during the stationary operation, and a maximum deviation of 30% during the dynamic load cycle. However, for both operational regimes the

  1. Hair-triggered instability of radial steady states, spread and extinction in semilinear heat equations

    Science.gov (United States)

    Shi, Junping; Wang, Xuefeng

    We first study the initial value problem for a general semilinear heat equation. We prove that every bounded nonconstant radial steady state is unstable if the spatial dimension is low ( n⩽10) or if the steady state is flat enough at infinity: the solution of the heat equation either becomes unbounded as t approaches the lifespan, or eventually stays above or below another bounded radial steady state, depending on if the initial value is above or below the first steady state; moreover, the second steady state must be a constant if n⩽10. Using this instability result, we then prove that every nonconstant radial steady state of the generalized Fisher equation is a hair-trigger for two kinds of dynamical behavior: extinction and spreading. We also prove more criteria on initial values for these types of behavior. Similar results for a reaction-diffusion system modeling an isothermal autocatalytic chemical reaction are also obtained.

  2. Study by similarity of wind influence on mass transfers in complex buildings

    International Nuclear Information System (INIS)

    Le Roux, Nicolas

    2011-01-01

    Residential and industrial buildings equipped with a ventilation system are complex facilities, where various heat and mass transfers could occur according to the operating conditions. In order to study these mass transfers, a methodology has been developed so as to carry out reduced-scale experiments for the study of isothermal flows, in steady or transient state. This methodology has been numerically and experimentally validated on simple configurations, and then applied to two standard configurations, representing nuclear facilities. The wind influence on mass transfers inside these configurations, in normal, damaged (stopping ventilation) or accidental (internal overpressure) situations, has been studied in the Jules Verne climatic wind tunnel of the CSTB. The wind effects, coupled or not with an internal overpressure, can lead to a partial or a total loss of the pollutant's containment inside buildings. Moreover, the wind turbulence can bring about instantaneous reversal leakage flow-rates, which cannot be identified in steady state. In addition, the study of transient phenomena has highlighted the low influence of the branch inertia on transient flows, for typical values of real facilities. Finally, tracer tests have been carried out in order to study the pollutant dispersion inside a standard configuration subjected to wind, mechanical ventilation and internal overpressure effects. The reliability of the zonal code SYLVIA, used notably to support safety assessment in nuclear buildings, has been analyzed from these experimental results. The modelling of the physical phenomena experimentally observed has been validated, in steady and transient states. However, limitations have been identified for the study of pollutant dispersion, due to hypothesis used in SYLVIA code, as in all zonal codes (homogenous concentration inside rooms, instantaneous propagation inside branches and rooms). (author)

  3. Evolution of Slow Dual Steady-State Optical Solitons in a Cold Three-State Medium

    International Nuclear Information System (INIS)

    Sun Jian-Qiang; Li Hao-Chen; Gu Xiao-Yan

    2012-01-01

    The generalized nonlinear Schrödinger equation, which describes the evolution of dual steady-state optical solitons in a cold three-state medium, is written as the Hamiltonian symplectic structure. The symplectic method is applied to investigate evolution of dual steady-state optical solitons. By adjusting the initial pulses, the saturation parameter variables and the distances of optical solitons, the different behaviors of dual steady-state optical solitons are analyzed. (fundamental areas of phenomenology(including applications))

  4. Two Dimensional Steady State Eddy Current Analysis of a Spinning Conducting Cylinder

    Science.gov (United States)

    2017-03-09

    UNCLASSIFIED UNCLASSIFIED AD-E403 855 Technical Report ARMET-TR-16045 TWO- DIMENSIONAL STEADY-STATE EDDY CURRENT ANALYSIS OF A...August 2014 4. TITLE AND SUBTITLE TWO- DIMENSIONAL STEADY-STATE EDDY CURRENT ANALYSIS OF A SPINNING CONDUCTING CYLINDER 5a. CONTRACT NUMBER 5b...analytical closed-form analysis performed by Michael P. Perry and Thomas B. Jones (ref. 4). Two- dimensional (2D) finite element steady state analyses

  5. Superconducting magnets and cryogenics for the steady state superconducting tokamak SST-1

    International Nuclear Information System (INIS)

    Saxena, Y.C.

    2000-01-01

    SST-1 is a steady state superconducting tokamak for studying the physics of the plasma processes in tokamak under steady state conditions and to learn technologies related to the steady state operation of the tokamak. SST-1 will have superconducting magnets made from NbTi based conductors operating at 4.5 K temperature. The design of the superconducting magnets and the cryogenic system of SST-1 tokamak are described. (author)

  6. STEADY STATE FLAMMABLE GAS RELEASE RATE CALCULATION & LOWER FLAMMABILITY LEVEL EVALUATION FOR HANFORD TANK WASTE [SEC 1 & 2

    Energy Technology Data Exchange (ETDEWEB)

    HU, T.A.

    2003-09-30

    Flammable gases such as hydrogen, ammonia, and methane are observed in the tank dome space of the Hanford Site high-level waste tanks. This report assesses the steady-state flammability level under normal and off-normal ventilation conditions in the tank dome space for 177 double-shell tanks and single-shell tanks at the Hanford Site. The steady-state flammability level was estimated from the gas concentration of the mixture in the dome space using estimated gas release rates, Le Chatelier's rule and lower flammability limits of fuels in an air mixture. A time-dependent equation of gas concentration, which is a function of the gas release and ventilation rates in the dome space, has been developed for both soluble and insoluble gases. With this dynamic model, the time required to reach the specified flammability level at a given ventilation condition can be calculated. In the evaluation, hydrogen generation rates can be calculated for a given tank waste composition and its physical condition (e.g., waste density, waste volume, temperature, etc.) using the empirical rate equation model provided in Empirical Rate Equation Model and Rate Calculations of Hydrogen Generation for Hanford Tank Waste, HNF-3851. The release rate of other insoluble gases and the mass transport properties of the soluble gas can be derived from the observed steady-state gas concentration under normal ventilation conditions. The off-normal ventilation rate is assumed to be natural barometric breathing only. A large body of data is required to do both the hydrogen generation rate calculation and the flammability level evaluation. For tank waste that does not have sample-based data, a statistical-based value from probability distribution regression was used based on data from tanks belonging to a similar waste group. This report (Revision 3) updates the input data of hydrogen generation rates calculation for 177 tanks using the waste composition information in the Best-Basis Inventory Detail

  7. Steady State Comparisons HAWC2 v12.2 vs HAWCStab2 v2.12

    DEFF Research Database (Denmark)

    Verelst, David Robert; Hansen, Morten Hartvig; Pirrung, Georg

    This reports presents comparison of the steady state HAWC2 [1] [2] [3] simulation results and the HAWCStab2 computations of the DTU10MW reference turbine [4] [5]. It serves as a simple validation for the HAWCStab2 [6] [7] [8] steady state computations.......This reports presents comparison of the steady state HAWC2 [1] [2] [3] simulation results and the HAWCStab2 computations of the DTU10MW reference turbine [4] [5]. It serves as a simple validation for the HAWCStab2 [6] [7] [8] steady state computations....

  8. A steady-state model of the lunar ejecta cloud

    Science.gov (United States)

    Christou, Apostolos

    2014-05-01

    Every airless body in the solar system is surrounded by a cloud of ejecta produced by the impact of interplanetary meteoroids on its surface [1]. Such ``dust exospheres'' have been observed around the Galilean satellites of Jupiter [2,3]. The prospect of long-term robotic and human operations on the Moon by the US and other countries has rekindled interest on the subject [4]. This interest has culminated with the - currently ongoing - investigation of the Moon's dust exosphere by the LADEE spacecraft [5]. Here a model is presented of a ballistic, collisionless, steady state population of ejecta launched vertically at randomly distributed times and velocities and moving under constant gravity. Assuming a uniform distribution of launch times I derive closed form solutions for the probability density functions (pdfs) of the height distribution of particles and the distribution of their speeds in a rest frame both at the surface and at altitude. The treatment is then extended to particle motion with respect to a moving platform such as an orbiting spacecraft. These expressions are compared with numerical simulations under lunar surface gravity where the underlying ejection speed distribution is (a) uniform (b) a power law. I discuss the predictions of the model, its limitations, and how it can be validated against near-surface and orbital measurements.[1] Gault, D. Shoemaker, E.M., Moore, H.J., 1963, NASA TN-D 1767. [2] Kruger, H., Krivov, A.V., Hamilton, D. P., Grun, E., 1999, Nature, 399, 558. [3] Kruger, H., Krivov, A.V., Sremcevic, M., Grun, E., 2003, Icarus, 164, 170. [4] Grun, E., Horanyi, M., Sternovsky, Z., 2011, Planetary and Space Science, 59, 1672. [5] Elphic, R.C., Hine, B., Delory, G.T., Salute, J.S., Noble, S., Colaprete, A., Horanyi, M., Mahaffy, P., and the LADEE Science Team, 2014, LPSC XLV, LPI Contr. 1777, 2677.

  9. Human auditory steady state responses to binaural and monaural beats.

    Science.gov (United States)

    Schwarz, D W F; Taylor, P

    2005-03-01

    Binaural beat sensations depend upon a central combination of two different temporally encoded tones, separately presented to the two ears. We tested the feasibility to record an auditory steady state evoked response (ASSR) at the binaural beat frequency in order to find a measure for temporal coding of sound in the human EEG. We stimulated each ear with a distinct tone, both differing in frequency by 40Hz, to record a binaural beat ASSR. As control, we evoked a beat ASSR in response to both tones in the same ear. We band-pass filtered the EEG at 40Hz, averaged with respect to stimulus onset and compared ASSR amplitudes and phases, extracted from a sinusoidal non-linear regression fit to a 40Hz period average. A 40Hz binaural beat ASSR was evoked at a low mean stimulus frequency (400Hz) but became undetectable beyond 3kHz. Its amplitude was smaller than that of the acoustic beat ASSR, which was evoked at low and high frequencies. Both ASSR types had maxima at fronto-central leads and displayed a fronto-occipital phase delay of several ms. The dependence of the 40Hz binaural beat ASSR on stimuli at low, temporally coded tone frequencies suggests that it may objectively assess temporal sound coding ability. The phase shift across the electrode array is evidence for more than one origin of the 40Hz oscillations. The binaural beat ASSR is an evoked response, with novel diagnostic potential, to a signal that is not present in the stimulus, but generated within the brain.

  10. Control, data acquisition and remote participation for steady-state operation in LHD

    International Nuclear Information System (INIS)

    Sudo, S.; Nagayama, Y.; Emoto, M.; Nakanishi, H.; Chikaraishi, H.; Imazu, S.; Iwata, C.; Kogi, Y.; Kojima, M.; Komada, S.; Kubo, S.; Kumazawa, R.; Mase, A.; Miyazawa, J.; Mutoh, T.; Nakamura, Y.; Nonomura, M.; Ohsuna, M.; Saito, K.; Sakamoto, R.; Seki, T.; Shoji, M.; Tsuda, K.; Yoshida, M.

    2006-01-01

    Control, data acquisition, plasma monitoring and remote participation for steady state operation in the large helical device (LHD) are reviewed. By controlling the impedance matching of ICH, the plasma position and the electron density, high temperature plasma is confined for 1905s. The plasma parameters are monitored in real time. Data are continuously sampled by the YOKOGAWA WE7000 system and by the NATIONAL INSTRUMENTS CompactPCI system. Those data are managed by the object-oriented database system based on ObjectStore in distributed servers with mass storage. By using the multi protocol label switching-virtual private network (MPLS-VPN) technology, the local area network of LHD is expanded to the Japanese fusion community. This provides the remote participants with the same environment of the LHD control room

  11. Control, data acquisition and remote participation for steady-state operation in LHD

    Energy Technology Data Exchange (ETDEWEB)

    Sudo, S. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan)]. E-mail: sudo@nifs.ac.jp; Nagayama, Y. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Emoto, M. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Nakanishi, H. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Chikaraishi, H. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Imazu, S. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Iwata, C. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Kogi, Y. [KASTEC, Kyushu University, Kasuga 816-8580 (Japan); Kojima, M. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Komada, S. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Kubo, S. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Kumazawa, R. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Mase, A. [KASTEC, Kyushu University, Kasuga 816-8580 (Japan); Miyazawa, J. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Mutoh, T. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Nakamura, Y. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Nonomura, M. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Ohsuna, M. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Saito, K. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Sakamoto, R.; Seki, T.; Shoji, M.; Tsuda, K.; Yoshida, M. [National Institute of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan)

    2006-07-15

    Control, data acquisition, plasma monitoring and remote participation for steady state operation in the large helical device (LHD) are reviewed. By controlling the impedance matching of ICH, the plasma position and the electron density, high temperature plasma is confined for 1905s. The plasma parameters are monitored in real time. Data are continuously sampled by the YOKOGAWA WE7000 system and by the NATIONAL INSTRUMENTS CompactPCI system. Those data are managed by the object-oriented database system based on ObjectStore in distributed servers with mass storage. By using the multi protocol label switching-virtual private network (MPLS-VPN) technology, the local area network of LHD is expanded to the Japanese fusion community. This provides the remote participants with the same environment of the LHD control room.

  12. Experimental and modeling studies of mass transfer in ...

    African Journals Online (AJOL)

    Gaining a better understanding of mass transfer problems in encapsulated cell systems and in tissue engineering requires both experimental investigations and mathematical modelling. Specific mass transfer studies are reviewed including oxygen transfer in immobilised animal cell culture systems, modelling of ...

  13. Mass transfer in nano-fluids: A review

    International Nuclear Information System (INIS)

    Ashrafmansouri, Seyedeh-Saba; Esfahany, Mohsen Nasr

    2014-01-01

    Growing attention has been recently paid to nano-fluids because of their potential for augmenting transfer processes - i.e., heat and mass transfer. Conflicting results have been reported in the literature on mass transfer in nano-fluids. The aim of this paper is to summarize the literature on mass transfer in nano-fluids stating the conflicts and possible reasons. Literature on mass transfer in nano-fluids has been reviewed in two sections. The first section concentrates on surveying mass diffusivity in nano-fluids while the second section focuses on convective mass transfer in nano-fluids. In each section, published articles, type of nano-fluids used, size and concentration range of nanoparticles, measurement methods, maximum observed enhancement, and suggested mass transport mechanisms are summarized. (authors)

  14. Development of Data Acquisition Set-up for Steady-state Experiments

    Science.gov (United States)

    Srivastava, Amit K.; Gupta, Arnab D.; Sunil, S.; Khan, Ziauddin

    2017-04-01

    For short duration experiments, generally digitized data is transferred for processing and storage after the experiment whereas in case of steady-state experiment the data is acquired, processed, displayed and stored continuously in pipelined manner. This requires acquiring data through special techniques for storage and on-the-go viewing data to display the current data trends for various physical parameters. A small data acquisition set-up is developed for continuously acquiring signals from various physical parameters at different sampling rate for long duration experiment. This includes the hardware set-up for signal digitization, Field Programmable Gate Arrays (FPGA) based timing system for clock synchronization and event/trigger distribution, time slicing of data streams for storage of data chunks to enable viewing of data during acquisition and channel profile display through down sampling etc. In order to store a long data stream of indefinite/long time duration, the data stream is divided into data slices/chunks of user defined time duration. Data chunks avoid the problem of non-access of server data until the channel data file is closed at the end of the long duration experiment. A graphical user interface has been developed in Lab VIEW application development environment for configuring the data acquisition hardware and storing data chunks on local machine as well as at remote data server through Python for further data access. The data plotting and analysis utilities have been developed with Python software, which provides tools for further data processing. This paper describes the development and implementation of data acquisition for steady-state experiment.

  15. Seasonal variations in ectotherm growth rates: Quantifying growth as an intermittent non steady state compensatory process

    Science.gov (United States)

    Guarini, J.-M.; Chauvaud, Laurent; Cloern, J.E.; Clavier, J.; Coston-Guarini, J.; Patry, Y.

    2011-01-01

    Generally, growth rates of living organisms are considered to be at steady state, varying only under environmental forcing factors. For example, these rates may be described as a function of light for plants or organic food resources for animals and these could be regulated (or not) by temperature or other conditions. But, what are the consequences for an individual's growth (and also for the population growth) if growth rate variations are themselves dynamic and not steady state? For organisms presenting phases of dormancy or long periods of stress, this is a crucial question. A dynamic perspective for quantifying short-term growth was explored using the daily growth record of the scallop Pecten maximus (L.). This species is a good biological model for ectotherm growth because the shell records growth striae daily. Independently, a generic mathematical function representing the dynamics of mean daily growth rate (MDGR) was implemented to simulate a diverse set of growth patterns. Once the function was calibrated with the striae patterns, the growth rate dynamics appeared as a forced damped oscillation during the growth period having a basic periodicity during two transitory phases (mean duration 43. days) and appearing at both growth start and growth end. This phase is most likely due to the internal dynamics of energy transfer within the organism rather than to external forcing factors. After growth restart, the transitory regime represents successive phases of over-growth and regulation. This pattern corresponds to a typical representation of compensatory growth, which from an evolutionary perspective can be interpreted as an adaptive strategy to coping with a fluctuating environment. ?? 2011 Elsevier B.V.

  16. Sulfur isotopic and proteomic profiles of sulfate reducers grown under differential steady-states

    Science.gov (United States)

    Leavitt, W.; Venceslau, S.; Waldbauer, J.; Smith, D. A.; Boidi, F. J.; Bradley, A. S.

    2016-12-01

    Microbial sulfate reducers (MSR) drive the Earth's biogeochemical sulfur cycle. At the heart of this energy metabolism is a cascade of redox transformations coupling organic carbon and/or hydrogen oxidation to the dissimilatory reduction of sulfate to sulfide. The product sulfide is depleted in the heavier isotopes of sulfur, relative to the reactant sulfate, consistent with a normal kinetic isotope effect. However, the magnitude of the net fractionation during MSR can range over a range of 70 permil, consistent with a multi-step set of reactions. This range in MSR fractionation has been shown to mainly depend on: i) the cell-specific sulfate reduction rate (csSRR), and ii) the ambient sulfate concentration. However, the fractionation under identical conditions differs among strains (Bradley et al. 2016. Geobio), and so must also be mediated by strain-specific processes, such as the nature and quantity of individual proteins involved in sulfate reduction, electron transport, and growth. In recent work we have examined the influence of electron donor, electron acceptor, and co-limitation under controlled steady-state culture conditions in order better inform models of MSR isotope fractionation, and the physiological and isotopic response to differential environmental forcings (e.g. Leavitt et al. (2013) PNAS). Recent models of the fractionation response to MSR rate (c.f. Bradley 2016; Wing & Halevy, 2016) make specific predictions for the responses of the cellular metabolome and proteome. Here we compare the steady-state S-isotopic fractionation and proteome of `fast' versus `slow' grown D. vulgaris, using replicate chemostats under electron donor limitation. We observe clear and statistically robust changes in some key central MSR and C-metabolism enzymes, though a host of the critical energy-transfer enzymes show no statistically discernable change. We discuss these results in light of recent theoretical advances and their relevance to modern and ancient

  17. Determination of kinetic parameters of Fe sup 3+ reduction mediated by a polyaniline film using steady-state and impedance methods

    Energy Technology Data Exchange (ETDEWEB)

    Deslouis, C. (LP15 du CNRS, Physique des Liquides et Electrochimie, Lab. de l' Univ. Pierre et Marie Curie, 75252 Paris Cedex 05 (FR)); Musiani, M.M.; Pagura, C.; Tribollet, C. (Inst. di Polarografia de Elettrochimica Preparativa del CNR, Corso Stati Uniti, 4, 35020 Camin, Padova (IT))

    1991-09-01

    This paper discusses the Fe{sup 3+} reduction reaction studied at Pt and polyaniline rotating disk electrodes by steady-state and impedance methods with the aim of testing the possibility of achieving the charge transfer resistance (R{sub ts}) of a redox reaction mediated by a conducting polymer film by ac impedance R{sub ts} was obtained as a function of electrode potential and rotation rate by nonlinear least squares fitting of a previously developed kinetic equation to the experimental data. These R{sub ts} values were combined with steady-state ones to calculate b{sub c} and k{sup 0}.

  18. Progress Towards High Performance, Steady-state Spherical Torus

    International Nuclear Information System (INIS)

    Ono, M.; Bell, M.G.; Bell, R.E.; Bigelow, T.; Bitter, M.; Blanchard, W.; Boedo, J.; Bourdelle, C.; Bush, C.; Choe, W.; Chrzanowski, J.; Darrow, D.S.; Diem, S.J.; Doerner, R.; Efthimion, P.C.; Ferron, J.R.; Fonck, R.J.; Fredrickson, E.D.; Garstka, G.D.; Gates, D.A.; Gray, T.; Grisham, L.R.; Heidbrink, W.; Hill, K.W.; Hoffman, D.; Jarboe, T.R.; Johnson, D.W.; Kaita, R.; Kaye, S.M.; Kessel, C.; Kim, J.H.; Kissick, M.W.; Kubota, S.; Kugel, H.W.; LeBlanc, B.P.; Lee, K.; Lee, S.G.; Lewicki, B.T.; Luckhardt, S.; Maingi, R.; Majeski, R.; Manickam, J.; Maqueda, R.; Mau, T.K.; Mazzucato, E.; Medley, S.S.; Menard, J.; Mueller, D.; Nelson, B.A.; Neumeyer, C.; Nishino, N.; Ostrander, C.N.; Pacella, D.; Paoletti, F.; Park, H.K.; Park, W.; Paul, S.F.; Peng, Y.-K. M.; Phillips, C.K.; Pinsker, R.; Probert, P.H.; Ramakrishnan, S.; Raman, R.; Redi, M.; Roquemore, A.L.; Rosenberg, A.; Ryan, P.M.; Sabbagh, S.A.; Schaffer, M.; Schooff, R.J.; Seraydarian, R.; Skinner, C.H.; Sontag, A.C.; Soukhanovskii, V.; Spaleta, J.; Stevenson, T.; Stutman, D.; Swain, D.W.; Synakowski, E.; Takase, Y.; Tang, X.; Taylor, G.; Timberlake, J.; Tritz, K.L.; Unterberg, E.A.; Von Halle, A.; Wilgen, J.; Williams, M.; Wilson, J.R.; Xu, X.; Zweben, S.J.; Akers, R.; Barry, R.E.; Beiersdorfer, P.; Bialek, J.M.; Blagojevic, B.; Bonoli, P.T.; Carter, M.D.; Davis, W.; Deng, B.; Dudek, L.; Egedal, J.; Ellis, R.; Finkenthal, M.; Foley, J.; Fredd, E.; Glasser, A.; Gibney, T.; Gilmore, M.; Goldston, R.J.; Hatcher, R.E.; Hawryluk, R.J.; Houlberg, W.; Harvey, R.; Jardin, S.C.; Hosea, J.C.; Ji, H.; Kalish, M.; Lowrance, J.; Lao, L.L.; Levinton, F.M.; Luhmann, N.C.; Marsala, R.; Mastravito, D.; Menon, M.M.; Mitarai, O.; Nagata, M.; Oliaro, G.; Parsells, R.; Peebles, T.; Peneflor, B.; Piglowski, D.; Porter, G.D.; Ram, A.K.; Rensink, M.; Rewoldt, G.; Roney, P.; Shaing, K.; Shiraiwa, S.; Sichta, P.; Stotler, D.; Stratton, B.C.; Vero, R.; Wampler, W.R.; Wurden, G.A.

    2003-01-01

    Research on the Spherical Torus (or Spherical Tokamak) is being pursued to explore the scientific benefits of modifying the field line structure from that in more moderate aspect-ratio devices, such as the conventional tokamak. The Spherical Tours (ST) experiments are being conducted in various U.S. research facilities including the MA-class National Spherical Torus Experiment (NSTX) at Princeton, and three medium-size ST research facilities: Pegasus at University of Wisconsin, HIT-II at University of Washington, and CDX-U at Princeton. In the context of the fusion energy development path being formulated in the U.S., an ST-based Component Test Facility (CTF) and, ultimately a Demo device, are being discussed. For these, it is essential to develop high-performance, steady-state operational scenarios. The relevant scientific issues are energy confinement, MHD stability at high beta (B), noninductive sustainment, ohmic-solenoid-free start-up, and power and particle handling. In the confinement area, the NSTX experiments have shown that the confinement can be up to 50% better than the ITER-98-pby2 H-mode scaling, consistent with the requirements for an ST-based CTF and Demo. In NSTX, CTF-relevant average toroidal beta values bT of up to 35% with the near unity central betaT have been obtained. NSTX will be exploring advanced regimes where bT up to 40% can be sustained through active stabilization of resistive wall modes. To date, the most successful technique for noninductive sustainment in NSTX is the high beta-poloidal regime, where discharges with a high noninductive fraction (∼60% bootstrap current + neutral-beam-injected current drive) were sustained over the resistive skin time. Research on radio-frequency-based heating and current drive utilizing HHFW (High Harmonic Fast Wave) and EBW (Electron Bernstein Wave) is also pursued on NSTX, Pegasus, and CDX-U. For noninductive start-up, the Coaxial Helicity Injection (CHI), developed in HIT/HIT-II, has been adopted

  19. Frequency Domain Characterization of the Somatosensory Steady State Response in Electroencephalography

    NARCIS (Netherlands)

    Vlaar, Martijn P.; van der Helm, Frans C.T.; Schouten, Alfred C.

    2015-01-01

    A continuous somatosensory stimulation evokes a steady state response in the cortex, which can be measured using electroencephalography. We applied mechanical multisine stimulation of the wrist to investigate the properties of the steady state response in the frequency domain. Our results show a

  20. Distance to achieve steady state walking speed in frail elderly persons

    NARCIS (Netherlands)

    Lindemann, U.; Najafi, B.; Zijlstra, W.; Hauer, K.; Muche, R.; Becker, C.; Aminian, K.

    This study aims to determine the length of the gait initiation phase before achieving steady state walking in frail older people. Based on body fixed sensors, habitual walking was analysed in 116 community-dwelling older persons (mean age 83.1 years, 84% women). The start of steady state walking was

  1. The steady state of a particle in a vibrating box and possible ...

    Indian Academy of Sciences (India)

    In particular, the parameter range is found in which the particle oscillates between the walls in steady state as if the wall was static and it is showed that for these parameter ranges the particle settles to this steady state for all initial conditions. It is proposed that this phenomenon can be used to bunch charged particles in ...

  2. 40 CFR Appendix C to Subpart S of... - Steady-State Short Test Standards

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Steady-State Short Test Standards C Appendix C to Subpart S of Part 51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED.../Maintenance Program Requirements Pt. 51, Subpt. S, App. C Appendix C to Subpart S of Part 51—Steady-State...

  3. Steady state, erosional continuity, and the topography of landscapes developed in layered rocks

    Science.gov (United States)

    Perne, Matija; Covington, Matthew D.; Thaler, Evan A.; Myre, Joseph M.

    2017-01-01

    The concept of topographic steady state has substantially informed our understanding of the relationships between landscapes, tectonics, climate, and lithology. In topographic steady state, erosion rates are equal everywhere, and steepness adjusts to enable equal erosion rates in rocks of different strengths. This conceptual model makes an implicit assumption of vertical contacts between different rock types. Here we hypothesize that landscapes in layered rocks will be driven toward a state of erosional continuity, where retreat rates on either side of a contact are equal in a direction parallel to the contact rather than in the vertical direction. For vertical contacts, erosional continuity is the same as topographic steady state, whereas for horizontal contacts it is equivalent to equal rates of horizontal retreat on either side of a rock contact. Using analytical solutions and numerical simulations, we show that erosional continuity predicts the form of flux steady-state landscapes that develop in simulations with horizontally layered rocks. For stream power erosion, the nature of continuity steady state depends on the exponent, n, in the erosion model. For n = 1, the landscape cannot maintain continuity. For cases where n ≠ 1, continuity is maintained, and steepness is a function of erodibility that is predicted by the theory. The landscape in continuity steady state can be quite different from that predicted by topographic steady state. For n stream power erosion model, continuity steady state provides a general mathematical tool that may also be useful to understand landscapes that develop by other erosion processes.

  4. Steady-state pharmacokinetics of sirolimus in stable adult Chinese renal transplant patients.

    Science.gov (United States)

    Wang, Huifen Faye; Qiu, Feng; Wu, Xiongfe; Fang, Juanzhi; Crownover, Penelope; Korth-Bradley, Joan; Schulman, Seth

    2014-05-01

    This open-label, nonrandomized study was conducted to evaluate the steady-state pharmacokinetics of sirolimus in 24 stable Chinese renal transplant patients receiving daily oral maintenance doses of sirolimus (1-4 mg). Repeated trough and serial whole blood sirolimus concentrations over a 24-hour dosing interval were collected and assayed using high-performance liquid chromatography with tandem mass spectrometry (HPLC/MS/MS). Non-compartmental analysis (NCA) was employed to calculate sirolimus pharmacokinetic parameters. Cytochrome P450 (CYP) 3A5 genotyping was performed. Cyclosporine (CsA) levels were determined for patients who took concomitant CsA. Mean (±SD) sirolimus maximum concentration (Cmax ), area under the concentration-time curve within a dosing interval of τ (AUCτ ), oral clearance (CL/F), and trough concentration (Ctrough ) at steady state were: 14.1 ± 13.4 ng/mL, 199 ± 210 ng · h/mL, 10.1 ± 4.4 L/h, and 5.9 ± 6.3 ng/mL, respectively. Median tmax (range) was 2.49 hours (1-12 hours). A strong correlation was observed between Ctrough and AUCτ . Pharmacokinetics of sirolimus in patients with and without concomitant CsA were comparable. Allele frequency of CYP3A5*3 was 70.9% and a trend of higher oral clearance was observed in CYP3A5 expressers compared with non-expressers although the number of subjects in each genotype was small. © 2014, The American College of Clinical Pharmacology.

  5. A steady-state target calculation method based on "point" model for integrating processes.

    Science.gov (United States)

    Pang, Qiang; Zou, Tao; Zhang, Yanyan; Cong, Qiumei

    2015-05-01

    Aiming to eliminate the influences of model uncertainty on the steady-state target calculation for integrating processes, this paper presented an optimization method based on "point" model and a method determining whether or not there is a feasible solution of steady-state target. The optimization method resolves the steady-state optimization problem of integrating processes under the framework of two-stage structure, which builds a simple "point" model for the steady-state prediction, and compensates the error between "point" model and real process in each sampling interval. Simulation results illustrate that the outputs of integrating variables can be restricted within the constraints, and the calculation errors between actual outputs and optimal set-points are small, which indicate that the steady-state prediction model can predict the future outputs of integrating variables accurately. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

  6. Numerical method for three dimensional steady-state two-phase flow calculations

    International Nuclear Information System (INIS)

    Raymond, P.; Toumi, I.

    1992-01-01

    This paper presents the numerical scheme which was developed for the FLICA-4 computer code to calculate three dimensional steady state two phase flows. This computer code is devoted to steady state and transient thermal hydraulics analysis of nuclear reactor cores 1,3 . The first section briefly describes the FLICA-4 flow modelling. Then in order to introduce the numerical method for steady state computations, some details are given about the implicit numerical scheme based upon an approximate Riemann solver which was developed for calculation of flow transients. The third section deals with the numerical method for steady state computations, which is derived from this previous general scheme and its optimization. We give some numerical results for steady state calculations and comparisons on required CPU time and memory for various meshing and linear system solvers

  7. Oxygen transfer and axial dispersion in an aeration tower containing static mixers.

    Science.gov (United States)

    Maclean, G T; Erickson, L E; Hsu, K H; Fan, L T

    1977-04-01

    Oxygen transfer from gas to liquid under steady-state cocurrent flow conditions was modeled using the dispersion model, and the oxygen transfer coefficients were estimated from available data for a column with Koch motionless mixers. The dispersion in the column was estimated for several different gas and liquid flow rates using steady-state tracer experiments. The estimated oxygen transfer coefficients were compared with those estimated using complete mixing and plug flow models. The results indicate that the dispersion model is the most appropriate model for estimating the mass transfer coefficient from the available data.

  8. Application of Lattice Boltzmann Methods in Complex Mass Transfer Systems

    Science.gov (United States)

    Sun, Ning

    similar steady state flux as the "brick and mortar" structure; however, in the early transient region, their flux value can be different. The influence of different system parameters (amount of drug in patch, patch thickness, partition coefficient at patch/ Stratum Corneum (SC) interface, and the diffusion coefficient of drug in each component) is discussed in details. It turns out that in this system, the rate-determine step for mass transfer should be the partition between patch and SC layers and the diffusion in the SC layer. The influence of enhancer is also tested. It is shown that by adding enhancers, the drug flux can be significantly increased. However, the peak time of drug does not necessarily match the peak flux time of enhancer. The peak time of drug could be adjusted (pushed earlier or dragged later) by using different kinds of enhancers, which has higher/smaller diffusivity than drug in the SC layer.

  9. Dosimetric adjustment factors for methyl methacrylate derived from a steady-state analysis of a physiologically based clearance-extraction model.

    Science.gov (United States)

    Andersen, M E; Sarangapani, R; Frederick, C B; Kimbell, J S

    1999-10-01

    Cells within the epithelial lining of the nasal cavity metabolize a variety of low-molecular-weight, volatile xenobiotics. In common with terminology developed for other metabolizing organs, the nose extracts these chemicals from the airstream, thereby clearing some portion of the total nasal airflow. In this article, a physiologically based clearance-extraction (PBCE) model of nasal metabolism is used to predict extraction for steady-state conditions. This model, developed by simplification of existing physiologically based pharmacokinetic (PBPK) nasal models, has three tissue regions in two flow paths. A dorsal flow stream sequentially passes over a small area of respiratory epithelium and then over the entire olfactory epithelial surface within the nose. A ventral airstream, consisting of most of the total flow, passes over the larger portion (>80%) of the respiratory epithelium. Each underlying tissue stack has a mucus layer, an epithelial tissue compartment, and a blood exchange region. Metabolism may occur in any of the subcompartments within the tissue stacks. The model, solved directly for a steady-state condition, specifies the volumetric airflow over each stack. Computational fluid dynamic (CFD) solutions for the rat and human for the case with no liquid-phase resistance provided a maximum value for regional extraction, E(max)'. Equivalent air-to-liquid phase permeation coefficients (also referred to as the air-phase mass transfer coefficient) were calculated based on these E(max)' values. The PBCE model was applied to assess expected species differences in nasal extraction and in localized tissue metabolism of methyl methacrylate (MMA) in rats and in humans. Model estimates of tissue dose of MMA metabolites (in micromol metabolized/h/ml tissue) in both species were used to evaluate the dosimetric adjustment factor (DAF) that should be applied in reference concentration (RfC) calculations for MMA. For human ventilation rates equivalent to light exercise

  10. On the steady state collisional evolution of debris disks around M dwarfs

    Science.gov (United States)

    Morey, Étienne; Lestrade, Jean-François

    2014-05-01

    Debris disks have been found primarily around intermediate and solar mass stars (spectral types A-K), but rarely around low-mass M-type stars. This scarcity of detections in M star surveys can be confronted with the predictions of the steady state collisional evolution model. First, we determine the parameters of the disk population evolved with this model and fit to the distribution of the fractional dust luminosities measured in the surveys of A- and FGK-type stars observed by the infrared satellite Spitzer. Thus, in our approach, we stipulate that the initial disk mass distribution is bimodal and that only high-mass collisionally-dominated disks are detected. The best determined parameter is the diameter Dc of the largest planetesimals in the collisional cascade of the model, which ranges between 2 and 60 km, consistently for disks around both A- and FGK-type stars. Second, we assume that the same disk population surrounds the M dwarfs that have been the subjects of debris disk searches in the far-infrared with Spitzer and at submillimeter wavelengths with radiotelescopes. We find, in the framework of our study, that this disk population, which has been fit to the AFGK data, is still consistent with the observed lack of disks around M dwarfs with Spitzer.

  11. Simulation of lean NOx trap performance with microkinetic chemistry and without mass transfer.

    Energy Technology Data Exchange (ETDEWEB)

    Larson, Rich; Daw, C. Stuart (Oak Ridge National Laboratory, Knoxville, TN); Pihl, Josh A. (Oak Ridge National Laboratory, Knoxville, TN); Chakravarthy, V. Kalyana (Oak Ridge National Laboratory, Knoxville, TN)

    2011-08-01

    A microkinetic chemical reaction mechanism capable of describing both the storage and regeneration processes in a fully formulated lean NO{sub x} trap (LNT) is presented. The mechanism includes steps occurring on the precious metal, barium oxide (NO{sub x} storage), and cerium oxide (oxygen storage) sites of the catalyst. The complete reaction set is used in conjunction with a transient plug flow reactor code to simulate not only conventional storage/regeneration cycles with a CO/H{sub 2} reductant, but also steady flow temperature sweep experiments that were previously analyzed with just a precious metal mechanism and a steady state code. The results show that NO{sub x} storage is not negligible during some of the temperature ramps, necessitating a re-evaluation of the precious metal kinetic parameters. The parameters for the entire mechanism are inferred by finding the best overall fit to the complete set of experiments. Rigorous thermodynamic consistency is enforced for parallel reaction pathways and with respect to known data for all of the gas phase species involved. It is found that, with a few minor exceptions, all of the basic experimental observations can be reproduced with these purely kinetic simulations, i.e., without including mass-transfer limitations. In addition to accounting for normal cycling behavior, the final mechanism should provide a starting point for the description of further LNT phenomena such as desulfation and the role of alternative reductants.

  12. Dynamics and steady-state properties of adaptive networks

    Science.gov (United States)

    Wieland, Stefan

    Collective phenomena often arise through structured interactions among a system's constituents. In the subclass of adaptive networks, the interaction structure coevolves with the dynamics it supports, yielding a feedback loop that is common in a variety of complex systems. To understand and steer such systems, modeling their asymptotic regimes is an essential prerequisite. In the particular case of a dynamic equilibrium, each node in the adaptive network experiences a perpetual change in connections and state, while a comprehensive set of measures characterizing the node ensemble are stationary. Furthermore, the dynamic equilibria of a wide class of adaptive networks appear to be unique, as their characteristic measures are insensitive to initial conditions in both state and topology. This work focuses on dynamic equilibria in adaptive networks, and while it does so in the context of two paradigmatic coevolutionary processes, obtained results easily generalize to other dynamics. In the first part, a low-dimensional framework is elaborated on using the adaptive contact process. A tentative description of the phase diagram and the steady state is obtained, and a parameter region identified where asymmetric microscopic dynamics yield a symmetry between node subensembles. This symmetry is accounted for by novel recurrence relations, which predict it for a wide range of adaptive networks. Furthermore, stationary nodeensemble distributions are analytically generated by these relations from one free parameter. Secondly, another analytic framework is put forward that detects and describes dynamic equilibria, while assigning to them general properties that must hold for a variety of adaptive networks. Modeling a single node's evolution in state and connections as a random walk, the ergodic properties of the network process are used to extract node-ensemble statistics from the node's long-term behavior. These statistical measures are composed of a variety of stationary

  13. NCEL: two dimensional finite element code for steady-state temperature distribution in seven rod-bundle

    International Nuclear Information System (INIS)

    Hrehor, M.

    1979-01-01

    The paper deals with an application of the finite element method to the heat transfer study in seven-pin models of LMFBR fuel subassembly. The developed code NCEL solves two-dimensional steady state heat conduction equation in the whole subassembly model cross-section and enebles to perform the analysis of thermal behaviour in both normal and accidental operational conditions as eccentricity of the central rod or full or partial (porous) blockage of some part of the cross-flow area. The heat removal is simulated by heat sinks in coolant under conditions of subchannels slug flow approximation

  14. REAL-TIME EMISSION CHARACTERIZATION OF ORGANIC AIR TOXIC POLLUTANTS DURING STEADY STATE AND TRANSIENT OPERATION OF A MEDIUM DUTY DIESEL ENGINE

    Science.gov (United States)

    An on-line monitoring method, jet resonance-enhanced multi-photon ionization (REMPI) with time-of-flight mass spectrometry (TOFMS) was used to measure emissions of organic air toxics from a medium-duty (60 kW)diesel generator during transient and steady state operations. Emission...

  15. Advancing metal-oxide-semiconductor theory: Steady-state nonequilibrium conditions

    Science.gov (United States)

    Passlack, M.; Hong, M.; Schubert, E. F.; Zydzik, G. J.; Mannaerts, J. P.; Hobson, W. S.; Harris, T. D.

    1997-06-01

    This article investigates steady-state nonequilibrium conditions in metal-oxide-semiconductor (MOS) capacitors. Steady-state nonequilibrium conditions are of significant interest due to the advent of wide-gap semiconductors in the arena of MOS (or metal-insulator-semiconductor) devices and due to the scaling of oxide thickness in Si technology. Two major classes of steady-state nonequilibrium conditions were studied both experimentally and theoretically: (i) steady-state deep depletion and (ii) steady-state low level optical generation. It is found that the identification and subsequent understanding of steady-state nonequilibrium conditions is of significant importance for correct interpretation of electrical measurements such as capacitance-voltage and conductance-voltage measurements. Basic implications of steady-state nonequilibrium conditions were derived for both MOS capacitors with low interfaces state density Dit and for oxide semiconductor interfaces with a pinned Fermi level. Further, a photoluminescence power spectroscopy technique is investigated as a complementary tool for direct-gap semiconductors to study Dit and to monitor the interface quality during device fabrication.

  16. Steady state creep of Zr-Nb alloys in a temperature interval 350 to 5500C

    International Nuclear Information System (INIS)

    Pahutova, M.; Cadek, J.

    1976-01-01

    Creep of three Zr-Nb alloys (0.5, 2.5 and 4.5 wt% Nb) was investigated in a temperature interval 350 to 550 0 C using the isothermal creep test and transmission electron microscopy techniques. Relations between steady-state creep rate and applied stress were determined; the parameter of applied stress sensitivity of steady-state creep rate increases with the applied stress, reaching values sometimes greater than 30 at 350 0 C. The apparent activation energy of creep was determined and the mean effective stress in steady-state creep measured. Possible creep-rate controlling mechanisms were discussed, with the conclusion that the creep is most probably recovery-controlled. Relations between steady state flow stress and temperature suggest a significant contribution of an athermal deformation mechanism to the measured steady-state strain rate at low temperatures and high applied stresses. The creep-strengthening effect of niobium increases linearly with niobium concentration at high steady-state creep rates, while at low steady-state creep rates the optimum niobium concentration does not exceed 2.5%. This, together with the temperature sensitivity of the strengthening effect of niobium, was explained by structural stability decreasing as niobium concentration increases from 2.5 to 4.5%. Creep-controlling mechanisms for very low creep rates are discussed. (Auth.)

  17. Assessing Quasi-Steady State in Evaporation of Sessile Drops by Diffusion Models

    Science.gov (United States)

    Martin, Cameron; Nguyen, Hoa; Kelly-Zion, Peter; Pursell, Chris

    2017-11-01

    The vapor distributions surrounding sessile drops of methanol are modeled as the solutions of the steady-state and transient diffusion equations using Matlab's PDE Toolbox. The goal is to determine how quickly the transient diffusive transport reaches its quasi-steady state as the droplet geometry is varied between a Weber's disc, a real droplet shape, and a spherical cap with matching thickness or contact angle. We assume that the only transport mechanism at work is diffusion. Quasi-steady state is defined using several metrics, such as differences between the transient and steady-state solutions, and change in the transient solution over time. Knowing the vapor distribution, the gradient is computed to evaluate the diffusive flux. The flux is integrated along the surface of a control volume surrounding the drop to obtain the net rate of diffusion out of the volume. Based on the differences between the transient and steady-state diffusive fluxes at the discrete points along the control-volume surface, the time to reach quasi-steady state evaporation is determined and is consistent with other proposed measurements. By varying the dimensions of the control volume, we can also assess what regimes have equivalent or different quasi-steady states for different droplet geometries. Petroleum Research Fund.

  18. Novel spacers for mass transfer enhancement in membrane separations

    NARCIS (Netherlands)

    Li, F.; Meindersma, G.W.; de Haan, A.B.; Reith, T.

    2005-01-01

    The optimal flow pattern for mass transfer enhancement in spacer-filled channels is characterized by the coexistence of transversal and longitudinal vortices in the flow close to the channel walls and minimal cross-flow power consumption in the middle of the channel. The mass transfer enhancement of

  19. Hydrodynamics and mass transfer in a tubular airlift photobioreactor

    NARCIS (Netherlands)

    Babcock Jr., R.W.; Malda, J.; Radway, J.C.

    2002-01-01

    In photobioreactors, which are usually operated under light limitation, sufficient dissolved inorganic carbon must be provided to avoid carbon limitation. Efficient mass transfer of CO2 into the culture medium is desirable since undissolved CO2 is lost by outgassing. Mass transfer of O2 out of the

  20. THE ELECTRONIC COURSE OF HEAT AND MASS TRANSFER

    Directory of Open Access Journals (Sweden)

    Alexander P. Solodov

    2013-01-01

    Full Text Available The Electronic course of heat and mass transfer in power engineering is presented containing the full Electronic book as the structured hypertext document, the full set of Mathcad-documents with the whole set of educative computer models of heat and mass transfer, the computer labs, and selected educational presentations. 

  1. Overall mass-transfer coefficients in non-linear chromatography

    DEFF Research Database (Denmark)

    Mollerup, Jørgen; Hansen, Ernst

    1998-01-01

    In case of mass transfer where concentration differences in both phases must be taken into account, one may define an over-all mass-transfer coefficient basd on the apparent over-all concentration difference. If the equilibrium relationship is linear, i.e. in cases where a Henry´s law relationshi...

  2. Limits of mass-transfer in parallel plate dialyzers

    NARCIS (Netherlands)

    Kolev, S.D.; Kolev, Spas D.; van der Linden, W.E.

    1992-01-01

    The absolute limits of mass transfer across the membrane in a parallel-plate dialyser set by the flow pattern in both channels were determined on the basis of a mathematical model assuming axially dispersed plug flow. The lower limit corresponds to the case of mass transfer under laminar flow

  3. Flow reversal in combined laminar mixed convection heat and mass transfer with phase change in a vertical channel

    International Nuclear Information System (INIS)

    Oulaid, Othmane; Benhamou, Brahim; Galanis, Nicolas

    2010-01-01

    This paper, deals with a numerical study of the effects of buoyancy forces on an upward, steady state, laminar flow of humid air in a vertical parallel-plate channel. The plates are wetted by a thin liquid water film and maintained at a constant temperature which is lower than that of the air entering the channel. A 2D fully elliptical model, associated with the Boussinesq assumption, is used to take into account axial diffusion. The solution of this mathematical model is based on the finite volume method and the velocity-pressure coupling is handled by the SIMPLER algorithm. Numerical results show that buoyancy forces have a significant effect on the hydrodynamic, thermal and mass fraction fields. Additionally, these forces induce flow reversal for high air temperatures and mass fractions at the channel entrance. It is established that heat transfer associated with phase change is, sometimes, more significant than sensible heat transfer. Furthermore, this importance depends on the mass fraction gradient. The conditions for the existence of flow reversal are presented in charts and analytical expressions specifying the critical thermal Grashof number as a function of the Reynolds number for different values of the solutal Grashof number and different aspect ratios of the channel.

  4. Steady State Performance Characteristics of Micropolar Lubricated Hydrodynamic Journal Bearings with Flexible Liner

    Science.gov (United States)

    Bansal, Pikesh; Chattopadhyay, Ajit Kumar; Agrawal, Vishnu Prakash

    2016-04-01

    The aim of the present study is to theoretically determine the steady state characteristics of hydrodynamic oil journal bearings considering the effect of deformation of liner and with micropolar lubrication. Modified Reynolds equation based on micropolar lubrication theory is solved using finite difference method to obtain steady state film pressures. Minimum film thickness is calculated taking into consideration the deformation of the liner. Parametric study has been conducted and steady state characteristics for journal bearing with elasticity of bearing liner are plotted for various values of eccentricity ratio, deformation factor, characteristic length and coupling number.

  5. On Steady-State Multiple Resonances for a Modified Bretherton Equation

    Science.gov (United States)

    Sun, Jianglong; Cui, Jifeng; He, Zihan; Liu, Zeng

    2017-05-01

    In this article, a modified Bretherton equation is considered to further check if steady-state multiple resonances exist not only for water waves but also for other dispersive medium. The linear resonance condition analysis shows that different components may interact with each other so multiple resonances may happen. Convergent steady-state solutions are obtained by solution procedure based on the homotopy analysis method (HAM) and the collocation method. Amplitude spectrum analysis confirms that more components indeed join the resonance as the nonlinearity increases. This article suggests that steady-state multiple resonance may exist in other dispersive system.

  6. Pre-steady-state Kinetics for Hydrolysis of Insoluble Cellulose by Cellobiohydrolase Cel7A

    DEFF Research Database (Denmark)

    Cruys-Bagger, Nicolaj; Olsen, Jens Elmerdahl; Præstgaard, Eigil

    2012-01-01

    The transient kinetic behavior of enzyme reactions prior to the establishment of steady state is a major source of mechanistic information, yet this approach has not been utilized for cellulases acting on their natural substrate, insoluble cellulose. Here, we elucidate the pre-steady-state regime...... for the exo-acting cellulase Cel7A using amperometric biosensors and an explicit model for processive hydrolysis of cellulose. This analysis allows the identification of a pseudo-steady-state period and quantification of a processivity number as well as rate constants for the formation of a threaded enzyme...

  7. Self-consistent steady state and dust-ion-acoustic soliton propagation in inhomogeneous plasmas

    International Nuclear Information System (INIS)

    Li Yangfang; Ma, J.X.

    2005-01-01

    The steady state of an inhomogeneous collisional dusty plasma is formulated self-consistently and the dust-ion-acoustic soliton propagation in such a plasma is studied by using the reductive perturbation method. The steady state is governed by the ambipolar diffusion theory, which includes the spatially varying collisions of electrons and ions with dust grains and is solved numerically with the boundary value problem. The effects of the nonuniformity of the equilibrium quantities on the solitons are considered. It is shown that the property of the solitons, especially the characteristic width, are sensitive to the variations of the steady state

  8. Simulation of multi-steady states in low temperature gas discharge

    International Nuclear Information System (INIS)

    Li Hong; Hu Xiwei

    2004-01-01

    This article presents hydrodynamics simulation of multi-steady states and mode transition by DC-beam-injected gas discharge, and provides a model approach to hysteresis and distinct forms of multi-steady states. The critical transition conditions of the three discharge modes (temperature limited mode, Langmuir mode, and space charge limited mode) are estimated to be dependent on the gas pressure and the filament temperature. Various forms of the multi-steady states in gas discharge can be uniformly explained by the displacement of the mutant positions. The simulation results are in a good agreement with those of the experiments. (authors)

  9. Calculating mass transfer from vertical wet fabrics using a free convection heat transfer correlation

    Energy Technology Data Exchange (ETDEWEB)

    Tafreshi, H. Vahedi; Ercan, E.; Pourdeyhimi, B. [North Carolina State University, Nonwovens Cooperative Research Center, Raleigh, NC (United States)

    2006-07-15

    In this note, the evaporation rate from a vertical wet fabric sheet is calculated using a free convection heat transfer correlation. Chilton-Colburn analogy is used to derive a mass transfer correlation from a heat transfer correlation proposed by Churchill and Chu for free convection from a vertical isothermal plate. The mass transfer rate obtained from this expression has shown excellent agreement with experimental data. (orig.)

  10. Pharmacokinetics of methadone during maintenance therapy: Pulse labeling with deuterated methadone in the steady state

    International Nuclear Information System (INIS)

    Aenggard, E.; Nilsson, M.I.; Holmstrand, J.; Gunne, L.M.; Uppsala Univ.; Karolinsky Institutet, Stockholm

    1979-01-01

    A technique is presented for study of steady state kinetics of methadone using pulse labeling with deuterated methadone (d 3 ) and mass fragmentography to measure both unlabeled and labeled methadone in blood. Seven subjects maintained on methadone for at least 10 months were admitted to a closed metabolic ward. The daily dose of unlabeled methadone (d 0 ) was substituted by one dose of methadone-d 3 and plasma levels of methadone-d 0 and methadone-d 3 were followed for 48 h using a precise (SD +- 5%) and sensitive (30 pmol/ml) mass fragmentographic technique. Plasma half-lives (tsub(1/2)) for both methadone-d 0 and methadone-d 3 were calculated from samples obtained 8-24 h following the dose of methadone-d 3 . The tsub(1/2) of oral methadone-d 3 was shorter (22 +- 2 h) than that of methadone-d 0 (52 +- 20 h). The same pattern was observed after intravenous administration. The results indicate multiple pools of methadone in the body. (orig.) 891 AJ/orig. 892 MKO [de

  11. The Energy Budget of Steady-State Photosynthesis

    Energy Technology Data Exchange (ETDEWEB)

    Kramer, David

    2007-06-30

    Our work developed a unique set of in vivo spectroscopic tools that have allowed us to probe the importance of 1) The effects of storage of proton motive force (pmf ) in the form of both electric field (Δψ) and pH difference (ΔpH); 2) alteration in the stoichiometry of proton pumping to electron transfer at key steps; 3) the influence of changes in the conductivity for proton efflux from the thylakoid of the ATP synthase; 4) the mechanisms of steps of the electron transfer process that pump protons; and 5) the mechanisms by which reactive O{sub 2} is generated as a side reaction to photosynthesis, and how these processes are minimized.

  12. Technical challenges in the construction of the steady-state stellarator Wendelstein 7-X

    Science.gov (United States)

    Bosch, H.-S.; Wolf, R. C.; Andreeva, T.; Baldzuhn, J.; Birus, D.; Bluhm, T.; Bräuer, T.; Braune, H.; Bykov, V.; Cardella, A.; Durodié, F.; Endler, M.; Erckmann, V.; Gantenbein, G.; Hartmann, D.; Hathiramani, D.; Heimann, P.; Heinemann, B.; Hennig, C.; Hirsch, M.; Holtum, D.; Jagielski, J.; Jelonnek, J.; Kasparek, W.; Klinger, T.; König, R.; Kornejew, P.; Kroiss, H.; Krom, J. G.; Kühner, G.; Laqua, H.; Laqua, H. P.; Lechte, C.; Lewerentz, M.; Maier, J.; McNeely, P.; Messiaen, A.; Michel, G.; Ongena, J.; Peacock, A.; Pedersen, T. S.; Riedl, R.; Riemann, H.; Rong, P.; Rust, N.; Schacht, J.; Schauer, F.; Schroeder, R.; Schweer, B.; Spring, A.; Stäbler, A.; Thumm, M.; Turkin, Y.; Wegener, L.; Werner, A.; Zhang, D.; Zilker, M.; Akijama, T.; Alzbutas, R.; Ascasibar, E.; Balden, M.; Banduch, M.; Baylard, Ch.; Behr, W.; Beidler, C.; Benndorf, A.; Bergmann, T.; Biedermann, C.; Bieg, B.; Biel, W.; Borchardt, M.; Borowitz, G.; Borsuk, V.; Bozhenkov, S.; Brakel, R.; Brand, H.; Brown, T.; Brucker, B.; Burhenn, R.; Buscher, K.-P.; Caldwell-Nichols, C.; Cappa, A.; Cardella, A.; Carls, A.; Carvalho, P.; Ciupiński, Ł.; Cole, M.; Collienne, J.; Czarnecka, A.; Czymek, G.; Dammertz, G.; Dhard, C. P.; Davydenko, V. I.; Dinklage, A.; Drevlak, M.; Drotziger, S.; Dudek, A.; Dumortier, P.; Dundulis, G.; Eeten, P. v.; Egorov, K.; Estrada, T.; Faugel, H.; Fellinger, J.; Feng, Y.; Fernandes, H.; Fietz, W. H.; Figacz, W.; Fischer, F.; Fontdecaba, J.; Freund, A.; Funaba, T.; Fünfgelder, H.; Galkowski, A.; Gates, D.; Giannone, L.; García Regaña, J. M.; Geiger, J.; Geißler, S.; Greuner, H.; Grahl, M.; Groß, S.; Grosman, A.; Grote, H.; Grulke, O.; Haas, M.; Haiduk, L.; Hartfuß, H.-J.; Harris, J. H.; Haus, D.; Hein, B.; Heitzenroeder, P.; Helander, P.; Heller, R.; Hidalgo, C.; Hildebrandt, D.; Höhnle, H.; Holtz, A.; Holzhauer, E.; Holzthüm, R.; Huber, A.; Hunger, H.; Hurd, F.; Ihrke, M.; Illy, S.; Ivanov, A.; Jablonski, S.; Jaksic, N.; Jakubowski, M.; Jaspers, R.; Jensen, H.; Jenzsch, H.; Kacmarczyk, J.; Kaliatk, T.; Kallmeyer, J.; Kamionka, U.; Karaleviciu, R.; Kern, S.; Keunecke, M.; Kleiber, R.; Knauer, J.; Koch, R.; Kocsis, G.; Könies, A.; Köppen, M.; Koslowski, R.; Koshurinov, J.; Krämer-Flecken, A.; Krampitz, R.; Kravtsov, Y.; Krychowiak, M.; Krzesinski, G.; Ksiazek, I.; Kubkowska, M.; Kus, A.; Langish, S.; Laube, R.; Laux, M.; Lazerson, S.; Lennartz, M.; Li, C.; Lietzow, R.; Lohs, A.; Lorenz, A.; Louche, F.; Lubyako, L.; Lumsdaine, A.; Lyssoivan, A.; Maaßberg, H.; Marek, P.; Martens, C.; Marushchenko, N.; Mayer, M.; Mendelevitch, B.; Mertens, Ph.; Mikkelsen, D.; Mishchenko, A.; Missal, B.; Mizuuchi, T.; Modrow, H.; Mönnich, T.; Morizaki, T.; Murakami, S.; Musielok, F.; Nagel, M.; Naujoks, D.; Neilson, H.; Neubauer, O.; Neuner, U.; Nocentini, R.; Noterdaeme, J.-M.; Nührenberg, C.; Obermayer, S.; Offermanns, G.; Oosterbeek, H.; Otte, M.; Panin, A.; Pap, M.; Paquay, S.; Pasch, E.; Peng, X.; Petrov, S.; Pilopp, D.; Pirsch, H.; Plaum, B.; Pompon, F.; Povilaitis, M.; Preinhaelter, J.; Prinz, O.; Purps, F.; Rajna, T.; Récsei, S.; Reiman, A.; Reiter, D.; Remmel, J.; Renard, S.; Rhode, V.; Riemann, J.; Rimkevicius, S.; Riße, K.; Rodatos, A.; Rodin, I.; Romé, M.; Roscher, H.-J.; Rummel, K.; Rummel, Th.; Runov, A.; Ryc, L.; Sachtleben, J.; Samartsev, A.; Sanchez, M.; Sano, F.; Scarabosio, A.; Schmid, M.; Schmitz, H.; Schmitz, O.; Schneider, M.; Schneider, W.; Scheibl, L.; Scholz, M.; Schröder, G.; Schröder, M.; Schruff, J.; Schumacher, H.; Shikhovtsev, I. V.; Shoji, M.; Siegl, G.; Skodzik, J.; Smirnow, M.; Speth, E.; Spong, D. A.; Stadler, R.; Sulek, Z.; Szabó, V.; Szabolics, T.; Szetefi, T.; Szökefalvi-Nagy, Z.; Tereshchenko, A.; Thomsen, H.; Thumm, M.; Timmermann, D.; Tittes, H.; Toi, K.; Tournianski, M.; Toussaint, U. v.; Tretter, J.; Tulipán, S.; Turba, P.; Uhlemann, R.; Urban, J.; Urbonavicius, E.; Urlings, P.; Valet, S.; Van Eester, D.; Van Schoor, M.; Vervier, M.; Viebke, H.; Vilbrandt, R.; Vrancken, M.; Wauters, T.; Weissgerber, M.; Weiß, E.; Weller, A.; Wendorf, J.; Wenzel, U.; Windisch, T.; Winkler, E.; Winkler, M.; Wolowski, J.; Wolters, J.; Wrochna, G.; Xanthopoulos, P.; Yamada, H.; Yokoyama, M.; Zacharias, D.; Zajac, J.; Zangl, G.; Zarnstorff, M.; Zeplien, H.; Zoletnik, S.; Zuin, M.

    2013-12-01

    The next step in the Wendelstein stellarator line is the large superconducting device Wendelstein 7-X, currently under construction in Greifswald, Germany. Steady-state operation is an intrinsic feature of stellarators, and one key element of the Wendelstein 7-X mission is to demonstrate steady-state operation under plasma conditions relevant for a fusion power plant. Steady-state operation of a fusion device, on the one hand, requires the implementation of special technologies, giving rise to technical challenges during the design, fabrication and assembly of such a device. On the other hand, also the physics development of steady-state operation at high plasma performance poses a challenge and careful preparation. The electron cyclotron resonance heating system, diagnostics, experiment control and data acquisition are prepared for plasma operation lasting 30 min. This requires many new technological approaches for plasma heating and diagnostics as well as new concepts for experiment control and data acquisition.

  13. Nonexistence of nonconstant steady-state solutions in a triangular cross-diffusion model

    Science.gov (United States)

    Lou, Yuan; Tao, Youshan; Winkler, Michael

    2017-05-01

    In this paper we study the Shigesada-Kawasaki-Teramoto model for two competing species with triangular cross-diffusion. We determine explicit parameter ranges within which the model exclusively possesses constant steady state solutions.

  14. Research on Steady States of Fuzzy Cognitive Map and its Application in Three-Rivers Ecosystem

    Directory of Open Access Journals (Sweden)

    Zhen Peng

    2016-01-01

    Full Text Available Fuzzy Cognitive Map (FCM offers many advantages such intuitive knowledge representation and fast numerical reasoning ability, etc. It suits modeling and decision-making of dynamic systems. With the aims to effectively help to analyze and control system sustainable evolution, the paper defines the steady states of fixed point and limited cycle of a FCM modeling system. Accordingly, the rules of steady states of the FCM model and the factors influencing the steady states are presented and proved. The Three-Rivers represents a system including population, ecological environment, social development and their relationships. Based on the relationships, the Three-Rivers ecosystem is modeled by FCM and the Three-Rivers ecosystemsustainable evolutionis analyzed bythe rules of the steady states of FCM.

  15. ROLE OF NMDA, NICOTINIC, AND GABA RECEPTORS IN THE STEADY STATE VISUAL EVOKED POTENTIAL IN RATS.

    Science.gov (United States)

    This manuscript characterizes the receptor pathways involved in pattern-evoked potential generation in rats" NMDA and nicotinic acetylcholine receptors appear to be involved in the generation of the steady-state pattern evoked response in vivo." The pattern evok...

  16. Navier-Stokes Predictions of Dynamic Stability Derivatives: Evaluation of Steady-State Methods

    National Research Council Canada - National Science Library

    DeSpirito, James; Silton, Sidra I; Weinacht, Paul

    2008-01-01

    The prediction of the dynamic stability derivatives-roll-damping, Magnus, and pitch-damping moments-were evaluated for three spin-stabilized projectiles using steady-state computational fluid dynamic (CFD) calculations...

  17. Steady state performance of subcritical and supercritical pressure natural circulation in the same test facility

    International Nuclear Information System (INIS)

    Swapnalee, B.T.; Vijayan, P.K; Sharma, Manish; Pilkhwal, D.S.; Saha, D.; Sinha, R.K.

    2011-01-01

    For supercritical pressure natural circulation loops, explicit correlation for steady state flow are not available. While using the subcritical natural circulation flow correlation for supercritical pressure data, it has been observed that subcritical flow correlation is not able to predict the steady state flow accurately near supercritical pressure condition. A generalized correlation has been proposed to estimate the steady state flow in supercritical pressure natural circulation loop based on a relationship between dimensionless density and dimensionless enthalpy reported in literature. This generalized correlation has been tested with the steady state supercritical pressure CO 2 data and found to be in good agreement. Subsequently supercritical pressure data for different working fluids reported in literature has also been compared with the proposed correlation. It is observed that the same generalized correlation is applicable for other fluids also. The present paper deals with the details of the test facility, the derivation of the generalized correlation and comparison with experimental data. (author)

  18. Measurements of Gene Expression at Steady State Improve the Predictability of Part Assembly.

    Science.gov (United States)

    Zhang, Haoqian M; Chen, Shuobing; Shi, Handuo; Ji, Weiyue; Zong, Yeqing; Ouyang, Qi; Lou, Chunbo

    2016-03-18

    Mathematical modeling of genetic circuits generally assumes that gene expression is at steady state when measurements are performed. However, conventional methods of measurement do not necessarily guarantee that this assumption is satisfied. In this study, we reveal a bi-plateau mode of gene expression at the single-cell level in bacterial batch cultures. The first plateau is dynamically active, where gene expression is at steady state; the second plateau, however, is dynamically inactive. We further demonstrate that the predictability of assembled genetic circuits in the first plateau (steady state) is much higher than that in the second plateau where conventional measurements are often performed. By taking the nature of steady state into consideration, our method of measurement promises to directly capture the intrinsic property of biological parts/circuits regardless of circuit-host or circuit-environment interactions.

  19. Pump two-phase performance program. Volume 5. Steady-state data. Final report

    International Nuclear Information System (INIS)

    Kennedy, W.G.; Jacob, M.C.; Whitehouse, J.C.; Fishburn, J.D.; Kanupka, G.J.

    1980-09-01

    Objective was to obtain steady-state and transient two-phase empirical data to substantiate and improve the reactor coolant pump analytical model currently used for LOCA analysis. A one-fifth scale pump was tested in steady-state runs with single- and two-phase mixtures of water and steam over ranges of operating conditions representative of postulated loss-of-coolant accidents. This volume contains tabulated data and derived parameters obtained for each of 962 selected steady-state test points conducted. A summary chronological listing of all 1322 steady-state test points actually conducted is also provided. The basic data are 67 channels of direct measurements for each test. Twenty-six derived parameters plus drift and standard deviations are calculated from the basic data and presented in the tabulation

  20. Calibration of steady-state car-following models using macroscopic loop detector data.

    Science.gov (United States)

    2010-05-01

    The paper develops procedures for calibrating the steady-state component of various car following models using : macroscopic loop detector data. The calibration procedures are developed for a number of commercially available : microscopic traffic sim...

  1. Development of MARS-LMR and Steady-state Calculation for KALIMER-600

    Energy Technology Data Exchange (ETDEWEB)

    Ha, K. S.; Jeong, H. Y.; Chang, W. P.; Lee, Y. B.; Jo, C. H

    2007-05-15

    MARS code which has been developed by coupling the RELAP and COBRA-TF in Korea Atomic Energy Research Institute has been improved in the aspects of hydraulically multi-dimensional modeling and data processing of common block using a dynamic memory allocation of FORTRAN. To use the code in the area of safety analysis of liquid metal reactor, several parts of the code have to be improved further. (1) Sodium property table including dynamic properties, such as, conductivity and viscosity, was generated to fit for the MARS code. (2) The heat transfer correlations for the liquid metal were implemented in the code. (3) The models describing the flow resistance by wire-wrap spacer in the core of LMR were applied. A MARS input data for KALIMER-600 is generated and steady-state calculation at the rated power is successfully performed. The input data can be used as a base input deck for the various transient analysis of a of PHTS, IHTS, and Tertiary system with minor revision of initial conditions and control system models.

  2. A comparison of pulsed and steady-state tokamak reactor burn cycles. Pt. 2

    International Nuclear Information System (INIS)

    Ehst, D.A.; Brooks, J.N.; Evans, K. Jr.; Kim, S.

    1985-01-01

    Pulsed operation of a tokamak reactor imposes cost penalties due to such problems as mechanical fatigue and the need to periodically transfer large amounts of energy to various reactor components. This study focuses on lifetime limitations and capital costs of reactor subsystems in an attempt to quantify sensitivity to pulsed operation. Major problem areas include: fatigue in pulsed poloidal field coils; out-of-plane bending fatigue in toroidal field coils; electric power supply costs; and noninductive current driver costs. A capital cost comparison is made for tokamak reactors operating under the four distinct operating cycles which have been proposed. Since high availability and a low cost of energy will be mandatory for a commercial fusion reactor, we can characterize improvements in physics and technology which will help achieve these goals for different burn cycles. A key conclusion is that steady-state operation is likely to result in the least expensive tokamak reactor (perhaps 20% cheaper than the best pulsed reactor), provided noninductive current drive efficiency can be increased roughly four-fold over present-day experimental results. (orig.)

  3. Research on steady-state visual evoked potentials in 3D displays

    Science.gov (United States)

    Chien, Yu-Yi; Lee, Chia-Ying; Lin, Fang-Cheng; Huang, Yi-Pai; Ko, Li-Wei; Shieh, Han-Ping D.

    2015-05-01

    Brain-computer interfaces (BCIs) are intuitive systems for users to communicate with outer electronic devices. Steady state visual evoked potential (SSVEP) is one of the common inputs for BCI systems due to its easy detection and high information transfer rates. An advanced interactive platform integrated with liquid crystal displays is leading a trend to provide an alternative option not only for the handicapped but also for the public to make our lives more convenient. Many SSVEP-based BCI systems have been studied in a 2D environment; however there is only little literature about SSVEP-based BCI systems using 3D stimuli. 3D displays have potentials in SSVEP-based BCI systems because they can offer vivid images, good quality in presentation, various stimuli and more entertainment. The purpose of this study was to investigate the effect of two important 3D factors (disparity and crosstalk) on SSVEPs. Twelve participants participated in the experiment with a patterned retarder 3D display. The results show that there is a significant difference (p-valuefuture.

  4. A lower limb exoskeleton control system based on steady state visual evoked potentials

    Science.gov (United States)

    Kwak, No-Sang; Müller, Klaus-Robert; Lee, Seong-Whan

    2015-10-01

    Objective. We have developed an asynchronous brain-machine interface (BMI)-based lower limb exoskeleton control system based on steady-state visual evoked potentials (SSVEPs). Approach. By decoding electroencephalography signals in real-time, users are able to walk forward, turn right, turn left, sit, and stand while wearing the exoskeleton. SSVEP stimulation is implemented with a visual stimulation unit, consisting of five light emitting diodes fixed to the exoskeleton. A canonical correlation analysis (CCA) method for the extraction of frequency information associated with the SSVEP was used in combination with k-nearest neighbors. Main results. Overall, 11 healthy subjects participated in the experiment to evaluate performance. To achieve the best classification, CCA was first calibrated in an offline experiment. In the subsequent online experiment, our results exhibit accuracies of 91.3 ± 5.73%, a response time of 3.28 ± 1.82 s, an information transfer rate of 32.9 ± 9.13 bits/min, and a completion time of 1100 ± 154.92 s for the experimental parcour studied. Significance. The ability to achieve such high quality BMI control indicates that an SSVEP-based lower limb exoskeleton for gait assistance is becoming feasible.

  5. Characterization of the Inlet Port Flow under Steady-State Conditions Using PIV and POD

    Directory of Open Access Journals (Sweden)

    Mohammed El-Adawy

    2017-11-01

    Full Text Available The current study demonstrates an experimental investigation of the tumble flow structures using Particle Image Velocimetry (PIV under steady-state conditions considering the central vertical tumble plane. The experiments were carried out on a four-valve, pent-roof Gasoline Direct Injection (GDI engine head at different valve lifts and with a pressure difference of 150 mmH2O across the intake valves. Furthermore, the Proper Orthogonal Decomposition (POD analytical technique was applied to PIV-measured velocity vector maps to characterize the flow structures at various valve lifts, and hence the different rig tumble values. The results show that at low valve lifts (1 to 5 mm, 48.9 to 46.6% of the flow energy is concentrated in the large (mode 1 eddies with only 8.4 to 11.46% in mode 2 and 7.2 to 7.5 in mode 3. At high valve lifts, it can be clearly seen that some of the energy in the large eddies of mode 1 is transferred to the smaller flow structures of modes 2 and 3. This can be clearly seen at valve lift 10 mm where the values of the flow energy were 40.6%, 17.3%, and 8.0% for modes 1, 2, and 3, respectively.

  6. RET: a computer code for solution of space-time dependent heat and mass transfer problem associated with metal hydrogen storage beds

    Energy Technology Data Exchange (ETDEWEB)

    El Osery, I.A.

    1981-01-01

    The computer code RET is developed for the solution of space-time dependent heat and mass transfer problem associated with a cylindrical metal hydride hydrogen storage bed where the heat transfer fluid is passing through a coaxial pipe. An approximate analytical solution is proposed on the assumption that an interface exists separating the completely reacted and unreacted zones and that heat is exhanged only at the interface. The bed is assumed initially at its equilibrium reaction temperature. The temperature distribution in the reacted zone is assumed of steady state type. The code gives as functions of time, the location of the reaction front, the cumulative reacted hydrogen, and the rate of hydrogen reaction. A listing of RET-code in FORTRAN is provided together with input data requirements and output facilities.

  7. A homotopy method based on WENO schemes for solving steady state problems of hyperbolic conservation laws

    Science.gov (United States)

    2012-09-03

    Numerical Solution of Polynomial Systems by Homotopy Con- tinuation Methods in Handbook of Numerical Analysis , Volume XI, Spe- cial Volume: Foundations of...A homotopy method based on WENO schemes for solving steady state problems of hyperbolic conservation laws Wenrui Hao∗ Jonathan D. Hauenstein† Chi...robustness of the new method . Keywords homotopy continuation, hyperbolic conservation laws, WENO scheme, steady state problems. ∗Department of Applied and

  8. Finite element modelling of creep process - steady state stresses and strains

    Directory of Open Access Journals (Sweden)

    Sedmak Aleksandar S.

    2014-01-01

    Full Text Available Finite element modelling of steady state creep process has been described. Using an analogy of visco-plastic problem with a described procedure, the finite element method has been used to calculate steady state stresses and strains in 2D problems. An example of application of such a procedure have been presented, using real life problem - cylindrical pipe with longitudinal crack at high temperature, under internal pressure, and estimating its residual life, based on the C*integral evaluation.

  9. Non-existence of Steady State Equilibrium in the Neoclassical Growth Model with a Longevity Trend

    DEFF Research Database (Denmark)

    Hermansen, Mikkel Nørlem

    of steady state equilibrium when considering the empirically observed trend in longevity. We extend a standard continuous time overlapping generations model by a longevity trend and are thereby able to study the properties of mortality-driven population growth. This turns out to be exceedingly complicated...... to handle, and it is shown that in general no steady state equilibrium exists. Consequently analytical results and long run implications cannot be obtained in a setting with a realistic demographic setup....

  10. Mathematical analysis of steady-state solutions in compartment and continuum models of cell polarization.

    Science.gov (United States)

    Zheng, Zhenzhen; Chou, Ching-Shan; Yi, Tau-Mu; Nie, Qing

    2011-10-01

    Cell polarization, in which substances previously uniformly distributed become asymmetric due to external or/and internal stimulation, is a fundamental process underlying cell mobility, cell division, and other polarized functions. The yeast cell S. cerevisiae has been a model system to study cell polarization. During mating, yeast cells sense shallow external spatial gradients and respond by creating steeper internal gradients of protein aligned with the external cue. The complex spatial dynamics during yeast mating polarization consists of positive feedback, degradation, global negative feedback control, and cooperative effects in protein synthesis. Understanding such complex regulations and interactions is critical to studying many important characteristics in cell polarization including signal amplification, tracking dynamic signals, and potential trade-off between achieving both objectives in a robust fashion. In this paper, we study some of these questions by analyzing several models with different spatial complexity: two compartments, three compartments, and continuum in space. The step-wise approach allows detailed characterization of properties of the steady state of the system, providing more insights for biological regulations during cell polarization. For cases without membrane diffusion, our study reveals that increasing the number of spatial compartments results in an increase in the number of steady-state solutions, in particular, the number of stable steady-state solutions, with the continuum models possessing infinitely many steady-state solutions. Through both analysis and simulations, we find that stronger positive feedback, reduced diffusion, and a shallower ligand gradient all result in more steady-state solutions, although most of these are not optimally aligned with the gradient. We explore in the different settings the relationship between the number of steady-state solutions and the extent and accuracy of the polarization. Taken together

  11. Introduction to computational mass transfer with applications to chemical engineering

    CERN Document Server

    Yu, Kuo-Tsung

    2017-01-01

    This book offers an easy-to-understand introduction to the computational mass transfer (CMT) method. On the basis of the contents of the first edition, this new edition is characterized by the following additional materials. It describes the successful application of this method to the simulation of the mass transfer process in a fluidized bed, as well as recent investigations and computing methods for predictions for the multi-component mass transfer process. It also demonstrates the general issues concerning computational methods for simulating the mass transfer of the rising bubble process. This new edition has been reorganized by moving the preparatory materials for Computational Fluid Dynamics (CFD) and Computational Heat Transfer into appendices, additions of new chapters, and including three new appendices on, respectively, generalized representation of the two-equation model for the CMT, derivation of the equilibrium distribution function in the lattice-Boltzmann method, and derivation of the Navier-S...

  12. Steady state effects in a two-pulse diffusion-weighted sequence.

    Science.gov (United States)

    Zubkov, Mikhail; Stait-Gardner, Timothy; Price, William S; Stilbs, Peter

    2015-04-21

    In conventional nuclear magnetic resonance (NMR) diffusion measurements a significant amount of experimental time is used up by magnetization recovery, serving to prevent the formation of the steady state, as in the latter case the manifestation of diffusion is modulated by multiple applications of the pulse sequence and conventional diffusion coefficient inference procedures are generally not applicable. Here, an analytical expression for diffusion-related effects in a two-pulse NMR experiment (e.g., pulsed-gradient spin echo) in the steady state mode (with repetition times less than the longitudinal relaxation time of the sample) is derived by employing a Fourier series expansion within the solution of the Bloch-Torrey equations. Considerations are given for the transition conditions between the full relaxation and the steady state experiment description. The diffusion coefficient of a polymer solution (polyethylene glycol) is measured by a two-pulse sequence in the full relaxation mode and for a range of repetition times, approaching the rapid steady state experiment. The precision of the fitting employing the presented steady state solution by far exceeds that of the conventional fitting. Additionally, numerical simulations are performed yielding results strongly supporting the proposed description of the NMR diffusion measurements in the steady state.

  13. Steady state effects in a two-pulse diffusion-weighted sequence

    International Nuclear Information System (INIS)

    Zubkov, Mikhail; Stait-Gardner, Timothy; Price, William S.; Stilbs, Peter

    2015-01-01

    In conventional nuclear magnetic resonance (NMR) diffusion measurements a significant amount of experimental time is used up by magnetization recovery, serving to prevent the formation of the steady state, as in the latter case the manifestation of diffusion is modulated by multiple applications of the pulse sequence and conventional diffusion coefficient inference procedures are generally not applicable. Here, an analytical expression for diffusion-related effects in a two-pulse NMR experiment (e.g., pulsed-gradient spin echo) in the steady state mode (with repetition times less than the longitudinal relaxation time of the sample) is derived by employing a Fourier series expansion within the solution of the Bloch-Torrey equations. Considerations are given for the transition conditions between the full relaxation and the steady state experiment description. The diffusion coefficient of a polymer solution (polyethylene glycol) is measured by a two-pulse sequence in the full relaxation mode and for a range of repetition times, approaching the rapid steady state experiment. The precision of the fitting employing the presented steady state solution by far exceeds that of the conventional fitting. Additionally, numerical simulations are performed yielding results strongly supporting the proposed description of the NMR diffusion measurements in the steady state

  14. When it pays to rush: interpreting morphogen gradients prior to steady-state

    International Nuclear Information System (INIS)

    Saunders, Timothy; Howard, Martin

    2009-01-01

    During development, morphogen gradients precisely determine the position of gene expression boundaries despite the inevitable presence of fluctuations. Recent experiments suggest that some morphogen gradients may be interpreted prior to reaching steady-state. Theoretical work has predicted that such systems will be more robust to embryo-to-embryo fluctuations. By analyzing two experimentally motivated models of morphogen gradient formation, we investigate the positional precision of gene expression boundaries determined by pre-steady-state morphogen gradients in the presence of embryo-to-embryo fluctuations, internal biochemical noise and variations in the timing of morphogen measurement. Morphogens that are direct transcription factors are found to be particularly sensitive to internal noise when interpreted prior to steady-state, disadvantaging early measurement, even in the presence of large embryo-to-embryo fluctuations. Morphogens interpreted by cell-surface receptors can be measured prior to steady-state without significant decrease in positional precision provided fluctuations in the timing of measurement are small. Applying our results to experiment, we predict that Bicoid, a transcription factor morphogen in Drosophila, is unlikely to be interpreted prior to reaching steady-state. We also predict that Activin in Xenopus and Nodal in zebrafish, morphogens interpreted by cell-surface receptors, can be decoded in pre-steady-state

  15. Reproducibility of hypercapnic ventilatory response measurements with steady-state and rebreathing methods.

    Science.gov (United States)

    Mannée, Denise C; Fabius, Timon M; Wagenaar, Michiel; Eijsvogel, Michiel M M; de Jongh, Frans H C

    2018-01-01

    In this study, the hypercapnic ventilatory response (HCVR) was measured, defined as the ventilation response to carbon dioxide tension ( P CO 2 ). We investigated which method, rebreathing or steady-state, is most suitable for measurement of the HCVR in healthy subjects, primarily based on reproducibility. Secondary outcome parameters were subject experience and duration. 20 healthy adults performed a rebreathing and steady-state HCVR measurement on two separate days. Subject experience was assessed using numeric rating scales (NRS). The intraclass correlation coefficient (ICCs) of the sensitivity to carbon dioxide above the ventilatory recruitment threshold and the projected apnoea threshold were calculated to determine the reproducibility of both methods. The ICCs of sensitivity were 0.89 (rebreathing) and 0.56 (steady-state). The ICCs of the projected apnoea threshold were 0.84 (rebreathing) and 0.25 (steady-state). The steady-state measurement was preferred by 16 out of 20 subjects; the differences in NRS scores were small. The hypercapnic ventilatory response measured using the rebreathing setup provided reproducible results, while the steady-state method did not. This may be explained by high variability in end-tidal P CO 2 . Differences in subject experience between the methods are small.

  16. 40 CFR 1033.515 - Discrete-mode steady-state emission tests of locomotives and locomotive engines.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Discrete-mode steady-state emission... Procedures § 1033.515 Discrete-mode steady-state emission tests of locomotives and locomotive engines. This... a warm-up followed by a sequence of nominally steady-state discrete test modes, as described in...

  17. Illustrating the Steady-State Condition and the Single-Molecule Kinetic Method with the NMDA Receptor

    Science.gov (United States)

    Kosman, Daniel J.

    2009-01-01

    The steady-state is a fundamental aspect of biochemical pathways in cells; indeed, the concept of steady-state is a definition of life itself. In a simple enzyme kinetic scheme, the steady-state condition is easy to define analytically but experimentally often difficult to capture because of its evanescent quality; the initial, constant velocity…

  18. Mass transfer study in the solvent extraction of lignite

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Tiejun; Yang Guilin

    1982-03-01

    The mass transfer study in the solvent extraction of Xundian lignite was performed in a flask with a stirrer. From experimental data, it can be seen that the mass transfer depends mainly on the particle size, extraction temperature, and time. For feed with smaller size, the extraction rate can be calculated by an external mass-transfer model and for larger size, it can be expressed by a diffusion model. A simple method of choice between the two methods is proposed. (13 refs.) (In Chinese)

  19. Model-based derivation, analysis and control of unstable microaerobic steady-states--considering Rhodospirillum rubrum as an example.

    Science.gov (United States)

    Carius, Lisa; Rumschinski, Philipp; Faulwasser, Timm; Flockerzi, Dietrich; Grammel, Hartmut; Findeisen, Rolf

    2014-04-01

    Microaerobic (oxygen-limited) conditions are critical for inducing many important microbial processes in industrial or environmental applications. At very low oxygen concentrations, however, the process performance often suffers from technical limitations. Available dissolved oxygen measurement techniques are not sensitive enough and thus control techniques, that can reliable handle these conditions, are lacking. Recently, we proposed a microaerobic process control strategy, which overcomes these restrictions and allows to assess different degrees of oxygen limitation in bioreactor batch cultivations. Here, we focus on the design of a control strategy for the automation of oxygen-limited continuous cultures using the microaerobic formation of photosynthetic membranes (PM) in Rhodospirillum rubrum as model phenomenon. We draw upon R. rubrum since the considered phenomenon depends on the optimal availability of mixed-carbon sources, hence on boundary conditions which make the process performance challenging. Empirically assessing these specific microaerobic conditions is scarcely practicable as such a process reacts highly sensitive to changes in the substrate composition and the oxygen availability in the culture broth. Therefore, we propose a model-based process control strategy which allows to stabilize steady-states of cultures grown under these conditions. As designing the appropriate strategy requires a detailed knowledge of the system behavior, we begin by deriving and validating an unstructured process model. This model is used to optimize the experimental conditions, and identify properties of the system which are critical for process performance. The derived model facilitates the good process performance via the proposed optimal control strategy. In summary the presented model-based control strategy allows to access and maintain microaerobic steady-states of interest and to precisely and efficiently transfer the culture from one stable microaerobic steady-state

  20. Landslide-driven drainage divide migration and quantifying progress toward topographic steady state

    Science.gov (United States)

    Dahlquist, M. P.; West, A. J.; Li, G.

    2017-12-01

    Drainage divide migration is a critical process in landscape evolution. It reorganizes river basins, redistributing fluvial erosive energy to facilitate mass balance, and contributes to feedbacks between tectonics, erosion, and climate. However, it leaves little straightforward evidence in the geologic or geomorphic record, and has been subject to minimal field study, hampering understanding its role in landscape evolution. Landslides link river channels, hillslopes, and ridges in steep landscapes, and thus play a central role in divide migration. In this study, we examine landslides triggered by three events: the 2008 Wenchuan Earthquake in central China, the 2015 Gorkha Earthquake in Nepal, and the 2009 Typhoon Morakot in southern Taiwan, seeking new insight into the controls on divide migration. Of the 100,000 landslides triggered, we mapped 367 which caused a divide to migrate, resulting in a total exchange of about 2 km2 between basins. We use this database of divide migrations to explore relationships between the geometry of rivers and the exchange of drainage area, comparing metrics which have been proposed as indicators of divide stability across mobile divides. We find that upstream-averaged local relief and upstream-averaged channel gradient predict the We propose a new metric to describe divide mobility and the overall influence of a reorganizing event on a landscape, using it to estimate the impact of events similar to the 2009 Typhoon Morakot on the progress of Taiwan's Central Range toward topographic steady state.

  1. Steady-state critical loads of acidity for forest soils in the Georgia Basin, British Columbia

    Directory of Open Access Journals (Sweden)

    Shaun A. WATMOUGH

    2010-08-01

    Full Text Available There has been growing interest in acid rain research in western Canada where sulphur (S and nitrogen (N emissions are expected to increase during the next two decades. One region of concern is southern British Columbia, specifically the Georgia Basin, where emissions are expected to increase owing to the expansion of industry and urban centres (Vancouver and Victoria. In the current study, weathering rates and critical loads of acidity (S and N for forest soils were estimated at nineteen sites located within the Georgia Basin. A base cation to aluminium ratio of 10 was selected as the critical chemical criterion associated with ecosystem damage. The majority of the sites (58% had low base cation weathering rates (≤50 meq m–2 y–1 based on the PROFILE model. Accordingly, mean critical load for the study sites, estimated using the steady-state mass balance model, ranged between 129–168 meq m–2 y–1. Annual average total (wet and dry S and N deposition during the period 2005–2006 (estimated by the Community Multiscale Air Quality model, exceeded critical load at five–nine of the study sites (mean exceedance = 32–46 meq m–2 y–1. The high-elevation (>1000 m study sites had shallow, acid sensitive, soils with low weathering rates; however, critical loads were predominantly exceeded at sites close to Vancouver under higher modelled deposition loads. The extent of exceedance is similar to other industrial regions in western and eastern Canada.

  2. Steady-State Simulation of Steam Reforming of INEEL Tank Farm Waste

    International Nuclear Information System (INIS)

    Nichols, T.T.; Taylor, D.D.; Wood, R.A.; Barnes, C.M. email toddn@inel.gov

    2002-01-01

    A steady-state model of the Sodium-Bearing Waste steam reforming process at the Idaho National Engineering and Environmental Laboratory has been performed using the commercial ASPEN Plus process simulator. The preliminary process configuration and its representation in ASPEN are described. As assessment of the capability of the model to mechanistically predict product stream compositions was made, and fidelity gaps and opportunities for model enhancement were identified, resulting in the following conclusions: (1) Appreciable benefit is derived from using an activity coefficient model for electrolyte solution thermodynamics rather than assuming ideality (unity assumed for all activity coefficients). The concentrations of fifteen percent of the species present in the primary output stream were changed by more than 50%, relative to Electrolyte NRTL, when ideality was assumed; (2) The current baseline model provides a good start for estimating mass balances and performing integrated process optimization because it contains several key species, uses a mechanistic electrolyte thermodynamic model, and is based on a reasonable process configuration; and (3) Appreciable improvement to model fidelity can be realized by expanding the species list and the list of chemical and phase transformations. A path forward is proposed focusing on the use of an improved electrolyte thermodynamic property method, addition of chemical and phase transformations for key species currently absent from the model, and the combination of RGibbs and Flash blocks to simulate simultaneous phase and chemical equilibria in the off-gas treatment train

  3. Caffeine Affects Time to Exhaustion and Substrate Oxidation during Cycling at Maximal Lactate Steady State.

    Science.gov (United States)

    Cruz, Rogério Santos de Oliveira; de Aguiar, Rafael Alves; Turnes, Tiago; Guglielmo, Luiz Guilherme Antonacci; Beneke, Ralph; Caputo, Fabrizio

    2015-06-30

    This study analyzed the effects of caffeine intake on whole-body substrate metabolism and exercise tolerance during cycling by using a more individualized intensity for merging the subjects into homogeneous metabolic responses (the workload associated with the maximal lactate steady state-MLSS). MLSS was firstly determined in eight active males (25 ± 4 years, 176 ± 7 cm, 77 ± 11 kg) using from two to four constant-load tests of 30 min. On two following occasions, participants performed a test until exhaustion at the MLSS workload 1 h after taking either 6 mg/kg of body mass of caffeine or placebo (dextrose), in a randomized, double-blinded manner. Respiratory exchange ratio was calculated from gas exchange measurements. There was an improvement of 22.7% in time to exhaustion at MLSS workload following caffeine ingestion (95% confidence limits of ±10.3%, p = 0.002), which was accompanied by decrease in respiratory exchange ratio (p = 0.001). These results reinforce findings indicating that sparing of the endogenous carbohydrate stores could be one of the several physiological effects of caffeine during submaximal performance around 1 h.

  4. Heat flux of driven granular mixtures at low density: Stability analysis of the homogeneous steady state

    Science.gov (United States)

    Khalil, Nagi; Garzó, Vicente

    2018-02-01

    The Navier-Stokes order hydrodynamic equations for a low-density driven granular mixture obtained previously [Khalil and Garzó, Phys. Rev. E 88, 052201 (2013), 10.1103/PhysRevE.88.052201] from the Chapman-Enskog solution to the Boltzmann equation are considered further. The four transport coefficients associated with the heat flux are obtained in terms of the mass ratio, the size ratio, composition, coefficients of restitution, and the driven parameters of the model. Their quantitative variation on the control parameters of the system is demonstrated by considering the leading terms in a Sonine polynomial expansion to solve the exact integral equations. As an application of these results, the stability of the homogeneous steady state is studied. In contrast to the results obtained in undriven granular mixtures, the stability analysis of the linearized Navier-Stokes hydrodynamic equations shows that the transversal and longitudinal modes are (linearly) stable with respect to long enough wavelength excitations. This conclusion agrees with a previous analysis made for single granular gases.

  5. Tailored parameter optimization methods for ordinary differential equation models with steady-state constraints.

    Science.gov (United States)

    Fiedler, Anna; Raeth, Sebastian; Theis, Fabian J; Hausser, Angelika; Hasenauer, Jan

    2016-08-22

    Ordinary differential equation (ODE) models are widely used to describe (bio-)chemical and biological processes. To enhance the predictive power of these models, their unknown parameters are estimated from experimental data. These experimental data are mostly collected in perturbation experiments, in which the processes are pushed out of steady state by applying a stimulus. The information that the initial condition is a steady state of the unperturbed process provides valuable information, as it restricts the dynamics of the process and thereby the parameters. However, implementing steady-state constraints in the optimization often results in convergence problems. In this manuscript, we propose two new methods for solving optimization problems with steady-state constraints. The first method exploits ideas from optimization algorithms on manifolds and introduces a retraction operator, essentially reducing the dimension of the optimization problem. The second method is based on the continuous analogue of the optimization problem. This continuous analogue is an ODE whose equilibrium points are the optima of the constrained optimization problem. This equivalence enables the use of adaptive numerical methods for solving optimization problems with steady-state constraints. Both methods are tailored to the problem structure and exploit the local geometry of the steady-state manifold and its stability properties. A parameterization of the steady-state manifold is not required. The efficiency and reliability of the proposed methods is evaluated using one toy example and two applications. The first application example uses published data while the second uses a novel dataset for Raf/MEK/ERK signaling. The proposed methods demonstrated better convergence properties than state-of-the-art methods employed in systems and computational biology. Furthermore, the average computation time per converged start is significantly lower. In addition to the theoretical results, the

  6. Heat and Mass Transfer in an L Shaped Porous Medium

    Science.gov (United States)

    Salman Ahmed, N. J.; Azeem; Yunus Khan, T. M.

    2017-08-01

    This article is an extension to the heat transfer in L-shaped porous medium by including the mass diffusion. The heat and mass transfer in the porous domain is represented by three coupled partial differential equations representing the fluid movement, energy transport and mass transport. The equations are converted into algebraic form of equations by the application of finite element method that can be conveniently solved by matrix method. An iterative approach is adopted to solve the coupled equations by setting suitable convergence criterion. The results are discussed in terms of heat transfer characteristics influenced by physical parameters such as buoyancy ratio, Lewis number, Rayleigh number etc. It is found that these physical parameters have significant effect on heat and mass transfer behavior of L-shaped porous medium.

  7. Convective heat and mass transfer in rotating disk systems

    CERN Document Server

    Shevchuk, Igor V

    2009-01-01

    The book describes results of investigations of a series of convective heat and mass transfer problems in rotating-disk systems. Methodology used included integral methods, self-similar and approximate analytical solutions, as well as CFD.

  8. Heat and mass transfer in frozen porous media

    NARCIS (Netherlands)

    Loon, van W.

    1991-01-01

    In this thesis processes and parameters associated with heat and mass transfer in frozen porous media both on a theoretical and empirical basis are studied. To obtain the required measurements some existing measuring methods needed to be

  9. Steady state flow evaluations for passive auxiliary feedwater system of APR

    International Nuclear Information System (INIS)

    Park, Jongha; Kim, Jaeyul; Seong, Hoje; Kang, Kyoungho

    2012-01-01

    This paper briefly introduces a methodology to evaluate steady state flow of APR+ Passive Auxiliary Feedwater System (PAFS). The PAFS is being developed as a safety grade passive system to completely replace the existing active Auxiliary Feedwater System (AFWS). Natural circulation cooling can be generally classified into the single-phase, two-phase, and boiling-condensation modes. The PAF is designed to be operated in a boiling-condensation natural circulation mode. The steady-state flow rate should be equal to the steady-state boiling/condensation rate determined by the steady-state energy and momentum balances in the PAFS. The determined steady-state flow rate can be used in the design optimization for the natural circulation loop of the PAFS through the steady-state momentum balance. Since the retarding force, which is to be balanced by the driving force in the natural circulation system design depends on the reliable evaluation of the success of a natural circulation system design depends on the reliable evaluation of the pressure loss coefficients. In PAFS, the core decay heat is released by natural circulation flow between the S G secondary side and the Passive Condensation Heat Exchanger (PCHX) that is immersed in the Passive Condensation Cooling Tank (PCCT). The PCCT is located on the top of Auxiliary building The driving force is determined by the difference between the S/G (heat Source) secondary water level and condensation liquid (heat sink) level. It will overcome retarding force at flowrate in the system, which is determined by vaporization and condensation of the steam which is generated at the S/G by the latent heat in system. In this study, the theoretical method to estimate the steady state flow rate in boiling-condensation natural circulation system is developed and compared with test results

  10. An Efficient Steady-State Analysis Method for Large Boolean Networks with High Maximum Node Connectivity.

    Science.gov (United States)

    Hong, Changki; Hwang, Jeewon; Cho, Kwang-Hyun; Shin, Insik

    2015-01-01

    Boolean networks have been widely used to model biological processes lacking detailed kinetic information. Despite their simplicity, Boolean network dynamics can still capture some important features of biological systems such as stable cell phenotypes represented by steady states. For small models, steady states can be determined through exhaustive enumeration of all state transitions. As the number of nodes increases, however, the state space grows exponentially thus making it difficult to find steady states. Over the last several decades, many studies have addressed how to handle such a state space explosion. Recently, increasing attention has been paid to a satisfiability solving algorithm due to its potential scalability to handle large networks. Meanwhile, there still lies a problem in the case of large models with high maximum node connectivity where the satisfiability solving algorithm is known to be computationally intractable. To address the problem, this paper presents a new partitioning-based method that breaks down a given network into smaller subnetworks. Steady states of each subnetworks are identified by independently applying the satisfiability solving algorithm. Then, they are combined to construct the steady states of the overall network. To efficiently apply the satisfiability solving algorithm to each subnetwork, it is crucial to find the best partition of the network. In this paper, we propose a method that divides each subnetwork to be smallest in size and lowest in maximum node connectivity. This minimizes the total cost of finding all steady states in entire subnetworks. The proposed algorithm is compared with others for steady states identification through a number of simulations on both published small models and randomly generated large models with differing maximum node connectivities. The simulation results show that our method can scale up to several hundreds of nodes even for Boolean networks with high maximum node connectivity. The

  11. Principles of heat and mass transfer

    CERN Document Server

    Incropera, Frank P; Bergman, Theodore L; Lavine, Adrienne S

    2013-01-01

    Completely updated, the seventh edition provides engineers with an in-depth look at the key concepts in the field. It incorporates new discussions on emerging areas of heat transfer, discussing technologies that are related to nanotechnology, biomedical engineering and alternative energy. The example problems are also updated to better show how to apply the material. And as engineers follow the rigorous and systematic problem-solving methodology, they'll gain an appreciation for the richness and beauty of the discipline.

  12. Heat and mass transfer in building services design

    CERN Document Server

    Moss, Keith

    1998-01-01

    Building design is increasingly geared towards low energy consumption. Understanding the fundamentals of heat transfer and the behaviour of air and water movements is more important than ever before. Heat and Mass Transfer in Building Services Design provides an essential underpinning knowledge for the technology subjects of space heating, water services, ventilation and air conditioning. This new text: *provides core understanding of heat transfer and fluid flow from a building services perspective *complements a range of courses in building services engineering *

  13. Mass transfer from smooth alabaster surfaces in turbulent flows

    Science.gov (United States)

    Opdyke, Bradley N.; Gust, Giselher; Ledwell, James R.

    1987-11-01

    The mass transfer velocity for alabaster plates in smooth-wall turbulent flow is found to vary with the friction velocity according to an analytic solution of the advective diffusion equation. Deployment of alabaster plates on the sea floor can perhaps be used to estimate the viscous stress, and transfer velocities for other species.

  14. Study of coupled heat and mass transfer during absorption of ...

    Indian Academy of Sciences (India)

    Mayer et al (1987) concluded from their numerical investigation that an excellent heat and mass transfer inside the reaction bed, good thermal contact of the bed material to the bed wall, and high external heat transfer coefficients were the important parameters to make the hydrogen absorption/desorption reaction efficient.

  15. Study of coupled heat and mass transfer during absorption of ...

    Indian Academy of Sciences (India)

    augments the heat transfer and reaction rate significantly. Jemni and his group predicted the dynamic heat and mass transfer characteristics in metal hydride bed during both absorption and desorption processes using two-dimensional model considering the variation of gas pres- sure inside the hydride bed (Faouzi et al ...

  16. Fluid dynamics and mass transfer in a gas centrifuge

    International Nuclear Information System (INIS)

    Conlisk, A.T.; Foster, M.R.; Walker, J.D.A.

    1982-01-01

    The fluid motion, temperature distribution and the mass-transfer problem of a binary gas mixture in a rapidly rotating centrifuge are investigated. Solutions for the velocity, temperature and mass-fraction fields within the centrifuge are obtained for mechanically or thermally driven centrifuges. For the mass-transfer problem, a detailed analysis of the fluid-mechanical boundary layers is required, and, in particular, mass fluxes within the boundary layers are obtained for a wide range of source-sink geometries. Solutions to the mass-transfer problem are obtained for moderately and strongly forced flows in the container; the dependence of the separation (or enrichment) factor on centrifuge configuration, rotational speed and fraction of the volumetric flow rate extracted at the product port (the cut) are predicted. (author)

  17. Epoxide hydrolase-catalyzed enantioselective conversion of trans-stilbene oxide: Insights into the reaction mechanism from steady-state and pre-steady-state enzyme kinetics.

    Science.gov (United States)

    Archelas, Alain; Zhao, Wei; Faure, Bruno; Iacazio, Gilles; Kotik, Michael

    2016-02-01

    A detailed kinetic study based on steady-state and pre-steady-state measurements is described for the highly enantioselective epoxide hydrolase Kau2. The enzyme, which is a member of the α/β-hydrolase fold family, preferentially reacts with the (S,S)-enantiomer of trans-stilbene oxide (TSO) with an E value of ∼200. The enzyme follows a classical two-step catalytic mechanism with formation of an alkyl-enzyme intermediate in the first step and hydrolysis of this intermediate in a rate-limiting second step. Tryptophan fluorescence quenching during TSO conversion appears to correlate with alkylation of the enzyme. The steady-state data are consistent with (S,S) and (R,R)-TSO being two competing substrates with marked differences in k(cat) and K(M) values. The high enantiopreference of the epoxide hydrolase is best explained by pronounced differences in the second-order alkylation rate constant (k2/K(S)) and the alkyl-enzyme hydrolysis rate k3 between the (S,S) and (R,R)-enantiomers of TSO. Our data suggest that during conversion of (S,S)-TSO the two active site tyrosines, Tyr(157) and Tyr(259), serve mainly as electrophilic catalysts in the alkylation half-reaction, polarizing the oxirane oxygen of the bound epoxide through hydrogen bond formation, however, without fully donating their hydrogens to the forming alkyl-enzyme intermediate. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Dynamic evolution of initial instability during non-steady-state growth.

    Science.gov (United States)

    Dong, Zhibo; Zheng, Wenjian; Wei, Yanhong; Song, Kuijing

    2014-06-01

    Dynamic evolution of initial instability is investigated by an analytic model obtained by modifying the theory of Warren and Langer [Phys. Rev. E 47, 2702 (1993)] and the quantitative phase-field model in directional solidification under transient conditions for realistic parameters of a dilute alloy. The evolutions of tip velocity and concentration in the liquid side of the interface predicted by the analytic model agree very well with that from the phase-field simulation in the linear growth stage of the non-steady-state growth, indicating that the model could be used as a convenient method to study the initial instability during non-steady-state growth. The influences of non-steady-state conditions which include the increasing rate of pulling speed and temperature gradient at the onset of initial instability are investigated, and we find that, the initial instability seems to depend strongly on the non-steady-state conditions and the non-steady-state history, and thus, it should be primarily considered in the study of the transient growth.

  19. A two-step iterative method for evolving nonlinear acoustic systems to a steady-state

    Science.gov (United States)

    Watson, Willie R.; Myers, Michael K.

    1990-01-01

    A new approach for evolving two-dimensional nonlinear acoustic systems with flow to a steady state is presented. The approach is a two-step iterative method which is tested on a benchmark acoustic problem for which an exact analytical solution is available. Results are also calculated for a nonlinear acoustic problem for which an exact analytical solution is not known. Results indicate that the two-step method represents a powerful, efficient, and stable method for evolving two-dimensional acoustic systems to a steady state, and that the method is applicable to any number of spatial dimensions and to other hyperbolic systems. It is noted that for the benchmark problem only a single iteration on the method is required when the transient and steady-state field are of the same order of magnitude; however, four iterations are required when the steady-state field is several orders of magnitude smaller than the transient field. This method requires six iterations before achieving a steady state for the nonlinear test problem.

  20. The Markov process admits a consistent steady-state thermodynamic formalism

    Science.gov (United States)

    Peng, Liangrong; Zhu, Yi; Hong, Liu

    2018-01-01

    The search for a unified formulation for describing various non-equilibrium processes is a central task of modern non-equilibrium thermodynamics. In this paper, a novel steady-state thermodynamic formalism was established for general Markov processes described by the Chapman-Kolmogorov equation. Furthermore, corresponding formalisms of steady-state thermodynamics for the master equation and Fokker-Planck equation could be rigorously derived in mathematics. To be concrete, we proved that (1) in the limit of continuous time, the steady-state thermodynamic formalism for the Chapman-Kolmogorov equation fully agrees with that for the master equation; (2) a similar one-to-one correspondence could be established rigorously between the master equation and Fokker-Planck equation in the limit of large system size; (3) when a Markov process is restrained to one-step jump, the steady-state thermodynamic formalism for the Fokker-Planck equation with discrete state variables also goes to that for master equations, as the discretization step gets smaller and smaller. Our analysis indicated that general Markov processes admit a unified and self-consistent non-equilibrium steady-state thermodynamic formalism, regardless of underlying detailed models.

  1. Paracetamol decreases steady-state exposure to lamotrigine by induction of glucuronidation in healthy subjects.

    Science.gov (United States)

    Gastrup, Sandra; Stage, Tore Bjerregaard; Fruekilde, Palle Bach Nielsen; Damkier, Per

    2016-04-01

    Patients receiving lamotrigine therapy frequently use paracetamol concomitantly. While one study suggests a possible, clinically relevant drug-drug interaction, practical recommendations of the concomitant use are inconsistent. We performed a systematic pharmacokinetic study in healthy volunteers to quantify the effect of 4 day treatment with paracetamol on the metabolism of steady-state lamotrigine. Twelve healthy, male volunteers participated in an open label, sequential interaction study. Lamotrigine was titrated to steady-state (100 mg daily) over 36 days, and blood and urine sampling was performed in a non-randomized order with and without paracetamol (1 g four times daily). The primary endpoint was change in steady-state area under the plasma concentration-time curve of lamotrigine. Secondary endpoints were changes in total apparent oral clearance, renal clearance, trough concentration of lamotrigine and formation clearance of lamotrigine glucuronide conjugates. Co-administration of lamotrigine and paracetamol decreased the steady-state area under the plasma concentration-time curve of lamotrigine by 20% (95% CI 10%, 25%; P steady-state lamotrigine glucuronidation, resulting in a 20% decrease in total systemic exposure and a 25% decrease in trough value of lamotrigine. This interaction may be of clinical relevance in some patients. © 2015 The British Pharmacological Society.

  2. Demonstration of the steady-state fluctuation theorem from a single trajectory

    International Nuclear Information System (INIS)

    Wang, G M; Carberry, D M; Reid, J C; Sevick, E M; Evans, D J

    2005-01-01

    The fluctuation theorem (FT) quantifies the probability of Second Law of Thermodynamics violations in small systems over short timescales. While this theorem has been experimentally demonstrated for systems that are perturbed from an initial equilibrium state, there are a number of studies suggesting that the theorem applies asymptotically in the long time limit to systems in a non-equilibrium steady state. The asymptotic application of the FT to such non-equilibrium steady-states has been referred to in the literature as the steady-state fluctuation theorem (or SSFT). In 2005 Wang et al demonstrated experimentally an integrated form of the SSFT using a colloidal bead that was weakly held in a circularly translating optical trap. Moreover, they showed that the integrated form of the FT may, for certain systems, hold under non-equilibrium steady states for all time, and not just in the long time limit, as suggested by the SSFT. While demonstration of the integrated forms of these theorems is compact and illustrative, a proper demonstration shows the theorem directly, rather than in its integrated form. In this paper, we present experimental results that demonstrate the SSFT directly, and show that the FT can hold for all time under non-equilibrium steady states

  3. Free-breathing steady-state free precession cine cardiac magnetic resonance with respiratory navigator gating.

    Science.gov (United States)

    Moghari, Mehdi H; Komarlu, Rukmini; Annese, David; Geva, Tal; Powell, Andrew J

    2015-04-01

    To develop and validate a respiratory motion compensation method for free-breathing cardiac cine imaging. A free-breathing navigator-gated cine steady-state free precession acquisition (Cine-Nav) was developed which preserves the equilibrium state of the net magnetization vector, maintains the high spatial and temporal resolutions of standard breath-hold (BH) acquisition, and images entire cardiac cycle. Cine image data is accepted only from cardiac cycles occurring entirely during end-expiration. Prospective validation was performed in 10 patients by obtaining in each three complete ventricular image stacks with different respiratory motion compensation approaches: (1) BH, (2) free-breathing with 3 signal averages (3AVG), and (3) free-breathing with Cine-Nav. The subjective image quality score (1 = worst, 4 = best) for Cine-Nav (3.8 ± 0.4) was significantly better than for 3AVG (2.2 ± 0.5, P = 0.002), and similar to BH (4.0 ± 0.0, P = 0.13). The blood-to-myocardium contrast ratio for Cine-Nav (6.3 ± 1.5) was similar to BH (5.9 ± 1.6, P = 0.52) and to 3AVG (5.6 ± 2.5, P = 0.43). There were no significant differences between Cine-Nav and BH for the ventricular volumes and mass. In contrast, there were significant differences between 3AVG and BH in all of these measurements but right ventricular mass. Free-breathing cine imaging with Cine-Nav yielded comparable image quality and ventricular measurements to BH, and was superior to 3AVG. © 2014 Wiley Periodicals, Inc.

  4. Geoelectrical Measurement of Multi-Scale Mass Transfer Parameters

    Energy Technology Data Exchange (ETDEWEB)

    Day-Lewis, Frederick David [US Geological Survey, Storrs, CT (United States); Singha, Kamini [Colorado School of Mines, Golden, CO (United States); Johnson, Timothy C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Haggerty, Roy [Oregon State Univ., Corvallis, OR (United States); Binley, Andrew [Lancaster Univ. (United Kingdom); Lane, John W. [US Geological Survey, Storrs, CT (United States)

    2014-11-25

    Mass transfer affects contaminant transport and is thought to control the efficiency of aquifer remediation at a number of sites within the Department of Energy (DOE) complex. An improved understanding of mass transfer is critical to meeting the enormous scientific and engineering challenges currently facing DOE. Informed design of site remedies and long-term stewardship of radionuclide-contaminated sites will require new cost-effective laboratory and field techniques to measure the parameters controlling mass transfer spatially and across a range of scales. In this project, we sought to capitalize on the geophysical signatures of mass transfer. Previous numerical modeling and pilot-scale field experiments suggested that mass transfer produces a geoelectrical signature—a hysteretic relation between sampled (mobile-domain) fluid conductivity and bulk (mobile + immobile) conductivity—over a range of scales relevant to aquifer remediation. In this work, we investigated the geoelectrical signature of mass transfer during tracer transport in a series of controlled experiments to determine the operation of controlling parameters, and also investigated the use of complex-resistivity (CR) as a means of quantifying mass transfer parameters in situ without tracer experiments. In an add-on component to our grant, we additionally considered nuclear magnetic resonance (NMR) to help parse mobile from immobile porosities. Including the NMR component, our revised study objectives were to: 1. Develop and demonstrate geophysical approaches to measure mass-transfer parameters spatially and over a range of scales, including the combination of electrical resistivity monitoring, tracer tests, complex resistivity, nuclear magnetic resonance, and materials characterization; and 2. Provide mass-transfer estimates for improved understanding of contaminant fate and transport at DOE sites, such as uranium transport at the Hanford 300 Area. To achieve our objectives, we implemented a 3

  5. Effect of steady-state faldaprevir on the pharmacokinetics of steady-state methadone and buprenorphine-naloxone in subjects receiving stable addiction management therapy.

    Science.gov (United States)

    Joseph, David; Schobelock, Michael J; Riesenberg, Robert R; Vince, Bradley D; Webster, Lynn R; Adeniji, Abidemi; Elgadi, Mabrouk; Huang, Fenglei

    2015-01-01

    The effects of steady-state faldaprevir on the safety, pharmacokinetics, and pharmacodynamics of steady-state methadone and buprenorphine-naloxone were assessed in 34 healthy male and female subjects receiving stable addiction management therapy. Subjects continued receiving a stable oral dose of either methadone (up to a maximum dose of 180 mg per day) or buprenorphine-naloxone (up to a maximum dose of 24 mg-6 mg per day) and also received oral faldaprevir (240 mg) once daily (QD) for 8 days following a 480-mg loading dose. Serial blood samples were taken for pharmacokinetic analysis. The pharmacodynamics of the opioid maintenance regimens were evaluated by the objective and subjective opioid withdrawal scales. Coadministration of faldaprevir with methadone or buprenorphine-naloxone resulted in geometric mean ratios for the steady-state area under the concentration-time curve from 0 to 24 h (AUC(0-24,ss)), the steady-state maximum concentration of the drug in plasma (C(max,ss)), and the steady-state concentration of the drug in plasma at 24 h (C(24,ss)) of 0.92 to 1.18 for (R)-methadone, (S)-methadone, buprenorphine, norbuprenorphine, and naloxone, with 90% confidence intervals including, or very close to including, 1.00 (no effect), suggesting a limited overall effect of faldaprevir. Although individual data showed moderate variability in the exposures between subjects and treatments, there was no evidence of symptoms of opiate overdose or withdrawal either during the coadministration of faldaprevir with methadone or buprenorphine-naloxone or after faldaprevir dosing was stopped. Similar faldaprevir exposures were observed in the methadone- and buprenorphine-naloxone-treated subjects. In conclusion, faldaprevir at 240 mg QD can be coadministered with methadone or buprenorphine-naloxone without dose adjustment, although given the relatively narrow therapeutic windows of these agents, monitoring for opiate overdose and withdrawal may still be appropriate. (This

  6. Steady-state plant model to predict hydrogen levels in power plant components

    Science.gov (United States)

    Glatzmaier, Greg C.; Cable, Robert; Newmarker, Marc

    2017-06-01

    The National Renewable Energy Laboratory (NREL) and Acciona Energy North America developed a full-plant steady-state computational model that estimates levels of hydrogen in parabolic trough power plant components. The model estimated dissolved hydrogen concentrations in the circulating heat transfer fluid (HTF), and corresponding partial pressures within each component. Additionally for collector field receivers, the model estimated hydrogen pressure in the receiver annuli. The model was developed to estimate long-term equilibrium hydrogen levels in power plant components, and to predict the benefit of hydrogen mitigation strategies for commercial power plants. Specifically, the model predicted reductions in hydrogen levels within the circulating HTF that result from purging hydrogen from the power plant expansion tanks at a specified target rate. Our model predicted hydrogen partial pressures from 8.3 mbar to 9.6 mbar in the power plant components when no mitigation treatment was employed at the expansion tanks. Hydrogen pressures in the receiver annuli were 8.3 to 8.4 mbar. When hydrogen partial pressure was reduced to 0.001 mbar in the expansion tanks, hydrogen pressures in the receiver annuli fell to a range of 0.001 mbar to 0.02 mbar. When hydrogen partial pressure was reduced to 0.3 mbar in the expansion tanks, hydrogen pressures in the receiver annuli fell to a range of 0.25 mbar to 0.28 mbar. Our results show that controlling hydrogen partial pressure in the expansion tanks allows us to reduce and maintain hydrogen pressures in the receiver annuli to any practical level.

  7. Steady-State Plant Model to Predict Hydroden Levels in Power Plant Components

    Energy Technology Data Exchange (ETDEWEB)

    Glatzmaier, Greg C.; Cable, Robert; Newmarker, Marc

    2017-06-27

    The National Renewable Energy Laboratory (NREL) and Acciona Energy North America developed a full-plant steady-state computational model that estimates levels of hydrogen in parabolic trough power plant components. The model estimated dissolved hydrogen concentrations in the circulating heat transfer fluid (HTF), and corresponding partial pressures within each component. Additionally for collector field receivers, the model estimated hydrogen pressure in the receiver annuli. The model was developed to estimate long-term equilibrium hydrogen levels in power plant components, and to predict the benefit of hydrogen mitigation strategies for commercial power plants. Specifically, the model predicted reductions in hydrogen levels within the circulating HTF that result from purging hydrogen from the power plant expansion tanks at a specified target rate. Our model predicted hydrogen partial pressures from 8.3 mbar to 9.6 mbar in the power plant components when no mitigation treatment was employed at the expansion tanks. Hydrogen pressures in the receiver annuli were 8.3 to 8.4 mbar. When hydrogen partial pressure was reduced to 0.001 mbar in the expansion tanks, hydrogen pressures in the receiver annuli fell to a range of 0.001 mbar to 0.02 mbar. When hydrogen partial pressure was reduced to 0.3 mbar in the expansion tanks, hydrogen pressures in the receiver annuli fell to a range of 0.25 mbar to 0.28 mbar. Our results show that controlling hydrogen partial pressure in the expansion tanks allows us to reduce and maintain hydrogen pressures in the receiver annuli to any practical level.

  8. Computer program for the equations describing the steady state of enzyme reactions.

    Science.gov (United States)

    Varon, R; Garcia-Sevilla, F; Garcia-Moreno, M; Garcia-Canovas, F; Peyro, R; Duggleby, R G

    1997-04-01

    The derivation of steady-state equations is frequently carried out in enzyme kinetic studies. Done manually, this becomes tedious and prone to human error. The computer programs now available which are able to accept reaction mechanisms of some complexity are focused only on the strict steady-state approach. Here we present a computer program called REFERASS, with a short computation time and a user-friendly format for the input and output files, able to derive the strict steady-state equations and/or those corresponding to the usual assumption that one ore more of the reversible steps are in rapid equilibrium. This program handles enzyme-catalysed reactions with mechanisms involving up to 255 enzyme species connected by up to 255 reaction steps, subject to limits imposed by the memory and disk space available.

  9. Time Reversibility, Correlation Decay and the Steady State Fluctuation Relation for Dissipation

    Directory of Open Access Journals (Sweden)

    Denis J. Evans

    2013-04-01

    Full Text Available Steady state fluctuation relations for nonequilibrium systems are under intense investigation because of their important practical implications in nanotechnology and biology. However the precise conditions under which they hold need clarification. Using the dissipation function, which is related to the entropy production of linear irreversible thermodynamics, we show time reversibility, ergodic consistency and a recently introduced form of correlation decay, called T-mixing, are sufficient conditions for steady state fluctuation relations to hold. Our results are not restricted to a particular model and show that the steady state fluctuation relation for the dissipation function holds near or far from equilibrium subject to these conditions. The dissipation function thus plays a comparable role in nonequilibrium systems to thermodynamic potentials in equilibrium systems.

  10. Sickle cell disease painful crisis and steady state differentiation by proton magnetic resonance.

    Science.gov (United States)

    Fernández, Adolfo A; Cabal, Carlos A; Lores, Manuel A; Losada, Jorge; Pérez, Enrique R

    2009-01-01

    The delay time of the Hb S polymerization process was investigated in 63 patients with sickle cell disease during steady state and 10 during painful crisis starting from spin-spin proton magnetic resonance (PMR) time behavior measured at 36 degrees C and during spontaneous deoxygenation. We found a significant decrease of delay time as a result of the crisis (36 +/- 10%) and two well-differentiated ranges of values for each state: 273-354 min for steady state and 166-229 min for crisis with an uncertainty region of 15%. It is possible to use PMR as an objective and quantitative method in order to differentiate both clinical conditions of the sickle cell patient, but a more clear differentiation can be established comparing the delay time (td) value of one patient during crisis with his own td value during steady state.

  11. Paracetamol decreases steady-state exposure to lamotrigine by induction of glucuronidation in healthy subjects

    DEFF Research Database (Denmark)

    Gastrup, Sandra; Stage, Tore Bjerregaard; Fruekilde, Palle Bach Nielsen

    2016-01-01

    AIM: Patients receiving lamotrigine therapy frequently use paracetamol concomitantly. While one study suggests a possible, clinically relevant drug-drug interaction, practical recommendations of the concomitant use are inconsistent. We performed a systematic pharmacokinetic study in healthy...... volunteers to quantify the effect of 4-day treatment of paracetamol on the metabolism of steady-state lamotrigine. METHODS: Twelve healthy, male volunteers participated in an open-label, sequential interaction study. Lamotrigine was titrated to steady state (100 mg daily) over 36 days, and blood and urine...... sampling was performed in a non-randomised order with and without paracetamol (1 g four times daily). The primary endpoint was change in steady-state area under the plasma concentration-time curve of lamotrigine. Secondary endpoints were changes in total apparent oral clearance, renal clearance...

  12. Steady-State Magneto-Optical Trap with 100-Fold Improved Phase-Space Density

    Science.gov (United States)

    Bennetts, Shayne; Chen, Chun-Chia; Pasquiou, Benjamin; Schreck, Florian

    2017-12-01

    We demonstrate a continuously loaded 88Sr magneto-optical trap (MOT) with a steady-state phase-space density of 1.3 (2 )×10-3 . This is 2 orders of magnitude higher than reported in previous steady-state MOTs. Our approach is to flow atoms through a series of spatially separated laser cooling stages before capturing them in a MOT operated on the 7.4-kHz linewidth Sr intercombination line using a hybrid slower+MOT configuration. We also demonstrate producing a Bose-Einstein condensate at the MOT location, despite the presence of laser cooling light on resonance with the 30-MHz linewidth transition used to initially slow atoms in a separate chamber. Our steady-state high phase-space density MOT is an excellent starting point for a continuous atom laser and dead-time free atom interferometers or clocks.

  13. Nonequilibrium steady states in correlated electron systems - Photoinduced insulator-metal transition and optical response

    International Nuclear Information System (INIS)

    Tsuji, Naoto; Oka, Takashi; Aoki, Hideo

    2010-01-01

    To reveal the nature of the photoinduced insulator-metal transition, we show that an exact analysis of the Falicov-Kimball model subject to external ac electric fields becomes possible with Floquet's method combined with the nonequilibrium dynamical mean-field theory. The nonequilibrium steady state that appears during irradiation of a pump light is shown to be determined if the dissipation in a certain heat-bath model is introduced. This has enabled us to predict that novel features characteristic of the photoexcited steady states, i.e., negative weight (gain) in the low-energy region and dip structures around the photon energy of the pump light, should be observed in the optical conductivity. Special emphasis is put on the role of dissipation, for which we elaborate the dependence of the steady state on the strength of dissipation and the temperature of the heat bath.

  14. Analysis on temperature distribution in density lock on steady state without disturbance

    International Nuclear Information System (INIS)

    Yu Pei; Yan Changqi; Gu Haifeng; Chen Wei

    2010-01-01

    Temperature distribution on steady state without disturbance in density lock is simulated experimentally in this paper, and the temperature stratification end point is discovered on the temperature curve on steady state. It separated the heat conduction layer and homoiothermy layer. Only when the temperature stratification end point is in the density lock, heat can be restrained effectually. The temperature field is simulated with three methods. The first one is a method of semi-infinite flat-panel heat conduction, the second one is a method of one dimensional steady state conduction in constant cross-section straight-fin, and the last one is calculated using Fluent calculation software. The results indicated that the method of semi-infinite flat-panel heat conduction is the best one to calculate the distribution of temperature and location of temperature stratification end point. (authors)

  15. Steady-state response of the electron distribution function to an applied electric field

    International Nuclear Information System (INIS)

    Wiley, J.C.; Hinton, F.L.

    1980-01-01

    Steady-state solutions to the linearized Fokker--Planck equation have been numerically investigated using two models. The Kulsrud model, in which the electron-electron collision term is simplified by evaluating the integrals using a Maxwellian distribution, is considered first. It is shown that steady-state solutions of the Kulsrud model, obtained by long time integrations of the time dependent equation, can be obtained more easily by considering a separable solution. A more physically reasonable steady-state model, which consistently describes both the thermal and runaway regimes and is readily solved numerically, is developed. The resistivity, in agreement with Spitzer and Haerm, and runaway production rates, in agreement with the Kulsrud model, are obtained

  16. Steady-state entanglement and thermalization of coupled qubits in two common heat baths

    Science.gov (United States)

    Hu, Li-Zhen; Man, Zhong-Xiao; Xia, Yun-Jie

    2018-03-01

    In this work, we study the steady-state entanglement and thermalization of two coupled qubits embedded in two common baths with different temperatures. The common bath is relevant when the two qubits are difficult to be isolated to only contact with their local baths. With the quantum master equation constructed in the eigenstate representation of the coupled qubits, we have demonstrated the variations of steady-state entanglement with respect to various parameters of the qubits' system in both equilibrium and nonequilibrium cases of the baths. The coupling strength and energy detuning of the qubits as well as the temperature gradient of the baths are found to be beneficial to the enhancement of the entanglement. We note a dark state of the qubits that is free from time-evolution and its initial population can greatly influence the steady-state entanglement. By virtues of effective temperatures, we also study the thermalization of the coupled qubits and their variations with energy detuning.

  17. The non-local Fisher–KPP equation: travelling waves and steady states

    International Nuclear Information System (INIS)

    Berestycki, Henri; Nadin, Grégoire; Perthame, Benoit; Ryzhik, Lenya

    2009-01-01

    We consider the Fisher–KPP equation with a non-local saturation effect defined through an interaction kernel φ(x) and investigate the possible differences with the standard Fisher–KPP equation. Our first concern is the existence of steady states. We prove that if the Fourier transform φ-circumflex(ξ) is positive or if the length σ of the non-local interaction is short enough, then the only steady states are u ≡ 0 and u ≡ 1. Next, we study existence of the travelling waves. We prove that this equation admits travelling wave solutions that connect u = 0 to an unknown positive steady state u ∞ (x), for all speeds c ≥ c * . The travelling wave connects to the standard state u ∞ (x) ≡ 1 under the aforementioned conditions: φ-circumflex(ξ) > 0 or σ is sufficiently small. However, the wave is not monotonic for σ large

  18. Mechanism of Non-Steady State Dissolution of Goethite in the Presence of Siderophores

    Science.gov (United States)

    Reichard, P. U.; Kretzschmar, R.; Kraemer, S. M.

    2003-12-01

    Iron is an essential micronutrient for almost all known organisms. Bacteria, fungi, and graminaceous plants are capable of exuding siderophores as part of an iron acquisition strategy. The production of these strong iron chelating ligands is induced by iron limited conditions. Grasses under iron stress, for example, exude phytosiderophores into the rhizosphere in a special diurnal rhythm (Roemheld and Marschner 1986). A few hours after sunrise the exudation starts, culminates around noon and is shut down again until about 4 hours after noon. The phytosiderophores diffuse into the rhizosphere (Marschner et al. 1986) and are passively back transported to the plants by advective flow induced by high transpiration around noon. Despite a fairly short residence time of the phytosiderophores in the rhizosphere, it is a very effective strategy for iron acquisition. To investigate the effect of such pulse inputs of siderophores on iron acquisition, we studied the dissolution mechanism of goethite (alpha-FeOOH), a mineral phase common in soils, under non-steady state conditions. In consideration of the chemical complexity of the rhizosphere, we also investigated the effect of other organic ligands commonly found in the rhizosphere (e. g. oxalate) on the dissolution kinetics. The dissolution experiments were conducted in batch reactors with a constant goethite solids concentration of 2.5 g/l, an ionic strength of 0.01 M, a pH of 6 and 100 microM oxalate. To induce non-steady state conditions, 3 mM phytosiderophores were added to a batch after the goethite-oxalate suspension reacted for a certain time period. Before the siderophore was added to the goethite-oxalate suspension, no dissolution of iron was observed. But, with the addition of the siderophore, a high rate was observed for the iron mobilization under these non-steady state conditions that subsequently was followed by a slow steady state dissolution rate. The results of these non-steady state experiments are very

  19. Introduction to computational mass transfer with applications to chemical engineering

    CERN Document Server

    Yu, Kuo-Tsong

    2014-01-01

    This book presents a new computational methodology called Computational Mass Transfer (CMT). It offers an approach to rigorously simulating the mass, heat and momentum transfer under turbulent flow conditions with the help of two newly published models, namely the C’2—εC’ model and the Reynolds  mass flux model, especially with regard to predictions of concentration, temperature and velocity distributions in chemical and related processes. The book will also allow readers to understand the interfacial phenomena accompanying the mass transfer process and methods for modeling the interfacial effect, such as the influences of Marangoni convection and Rayleigh convection. The CMT methodology is demonstrated by means of its applications to typical separation and chemical reaction processes and equipment, including distillation, absorption, adsorption and chemical reactors. Professor Kuo-Tsong Yu is a Member of the Chinese Academy of Sciences. Dr. Xigang Yuan is a Professor at the School of Chemical Engine...

  20. Analysis of physical properties controlling steady-state infiltration rates on tropical savannah soils

    International Nuclear Information System (INIS)

    Mbagwu, J.S.C.

    1993-10-01

    A knowledge of physical properties influencing the steady-state infiltration rates (ic) of soils is needed for the hydrologic modelling of the infiltration process. In this study evidence is provided to show that effective porosity (Pe) (i.e. the proportion of macro pore spaces with equivalent radius of > 15 μm) and dry bulk density are the most important soil physical properties controlling the steady-state infiltration rates on a tropical savannah with varying land use histories. At a macro porosity value of ≤ 5.0% the steady-state infiltration rate is zero. Total porosity and the proportion of water-retaining pores explained only a small fraction of the variation in this property. Steady-state infiltration rates can also be estimated from either the saturated hydraulic conductivity (Ks) by the equation, i c = 31.1 + 1.06 (Ks), (R 2 = 0.8104, p ≤ 0.001) or the soil water transmissivity (A) by the equation, i c = 30.0 + 29.9(A), (R 2 = 0.8228, ρ ≤ 0.001). The Philip two-parameter model under predicted steady-state infiltration rates generally. Considering the ease of determination and reliability it is suggested that effective porosity be used to estimate the steady-state infiltration rates of these other soils with similar characteristics. The model is, i c 388.7(Pe) - 10.8(R 2 = 0.7265, p ≤ 0.001) where i c is in (cm/hr) and Pe in (cm 3 /cm 3 ). (author). 20 refs, 3 figs, 4 tabs

  1. The Energy Cost of Steady State Physical Activity in Acute Stroke.

    Science.gov (United States)

    Kramer, Sharon Flora; Cumming, Toby; Bernhardt, Julie; Johnson, Liam

    2018-04-01

    Cardiorespiratory fitness levels are very low after stroke, indicating that the majority of stroke survivors are unable to independently perform daily activities. Physical fitness training improves exercise capacity poststroke; however, the optimal timing and intensity of training is unclear. Understanding the energy cost of steady-state activity is necessary to guide training prescription early poststroke. We aimed to determine if acute stroke survivors can reach steady state (oxygen-uptake variability ≤2.0 mL O 2 /kg/min) during physical activity and if the energy cost of steady state activity differs from healthy controls. We recruited 23 stroke survivors less than 2 weeks poststroke. Thirteen were able to walk independently and performed a 6-minute walk (median age 78 years, interquartile range [IQR] 70-85), and 7 who were unable to walk independently performed 6 minutes of continuous sit-to-stands (median age 78 years, IQR 74-79) and we recruited 10 healthy controls (median age 73 years, IQR 70-77) who performed both 6 minutes of walking and sit-to-stands. Our primary outcome was energy cost (oxygen-uptake) during steady state activity (i.e., walking and continuous) sit-to-stands, measured by a mobile metabolic cart. All stroke survivors were able to reach steady state. Energy costs of walking was higher in stroke than in controls (mean difference .10 mL O 2 /kg/m, P = .02); the difference in energy costs during sit-to-stands was not significant (mean difference .11 mL O 2 /kg/sts, P = .45). Acute stroke survivors can reach a steady state during activity, indicating they are able to perform cardiorespiratory exercise. Acute stroke survivors require more energy per meter walked than controls. Copyright © 2018 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  2. Analysis on the steady-state coherent synchrotron radiation with strong shielding

    International Nuclear Information System (INIS)

    Li, R.; Bohn, C.L.; Bisognano, J.J.

    1997-01-01

    There are several papers concerning shielding of coherent synchrotron radiation (CSR) emitted by a Gaussian line charge on a circular orbit centered between two parallel conducting plates. Previous asymptotic analyses in the frequency domain show that shielded steady-state CSR mainly arises from harmonics in the bunch frequency exceeding the threshold harmonic for satisfying the boundary conditions at the plates. In this paper the authors extend the frequency-domain analysis into the regime of strong shielding, in which the threshold harmonic exceeds the characteristic frequency of the bunch. The result is then compared to the shielded steady-state CSR power obtained using image charges

  3. Steady-State PMU Compliance Test under C37.118.1a-2014

    DEFF Research Database (Denmark)

    Ghiga, Radu; Wu, Qiuwei; Martin, Kenneth E.

    2016-01-01

    This paper presents a flexible testing method and the steady-state compliance of PMUs under the C37.118.1a amendment. The work is focused on the changes made to the standard for the harmonic rejection and out-of-band interference tests for which the ROCOF Error limits have been suspended. The paper...... vendors were tested simultaneously in order to provide a fair comparison of the devices. The results for the steady state tests are discussed in the paper together with the strengths and weaknesses of the PMUs and of the test setup....

  4. Modified fluctuation-dissipation and Einstein relation at nonequilibrium steady states.

    Science.gov (United States)

    Chaudhuri, Debasish; Chaudhuri, Abhishek

    2012-02-01

    Starting from the pioneering work of Agarwal [G. S. Agarwal, Zeitschrift für Physik 252, 25 (1972)], we present a unified derivation of a number of modified fluctuation-dissipation relations (MFDR) that relate response to small perturbations around nonequilibrium steady states to steady-state correlations. Using this formalism we show the equivalence of velocity forms of MFDR derived using continuum Langevin and discrete master equation dynamics. The resulting additive correction to the Einstein relation is exemplified using a flashing ratchet model of molecular motors. © 2012 American Physical Society

  5. Local wettability reversal during steady-state two-phase flow in porous media.

    Science.gov (United States)

    Sinha, Santanu; Grøva, Morten; Ødegården, Torgeir Bryge; Skjetne, Erik; Hansen, Alex

    2011-09-01

    We study the effect of local wettability reversal on remobilizing immobile fluid clusters in steady-state two-phase flow in porous media. We consider a two-dimensional network model for a porous medium and introduce a wettability alteration mechanism. A qualitative change in the steady-state flow patterns, destabilizing the percolating and trapped clusters, is observed as the system wettability is varied. When capillary forces are strong, a finite wettability alteration is necessary to move the system from a single-phase to a two-phase flow regime. When both phases are mobile, we find a linear relationship between fractional flow and wettability alteration.

  6. Steady-State Numerical Modeling of Size Effects in Wire Drawing

    DEFF Research Database (Denmark)

    Juul, Kristian Jørgensen; Nielsen, Kim Lau; Niordson, Christian Frithiof

    2016-01-01

    Wire drawing processes at micron scale receive increased interest as micro wires are increasingly required in micro electrical components. At the micron scale, size effects become important and have to be taken into consideration. The goal is to optimize the semi-cone angle of the tool in terms...... of drawing force. The present study employs a steady-state modelling technique that omits the transient regime, thus creating a basis for comprehensive parameter studies. The steady-state procedure is based on the streamline integration method presented by Dean and Hutchinson [1]. This approach allows...

  7. 7. IAEA Technical Meeting on Steady State Operation of Magnetic Fusion Devices - Booklet of abstracts

    International Nuclear Information System (INIS)

    2015-01-01

    This meeting has provided an appropriate forum to discuss current issues covering a wide range of technical topics related to the steady state operation issues and also to encourage forecast of the ITER performances. The technical meeting includes invited and contributed papers. The topics that have been dealt with are: 1) Superconducting devices (ITER, KSTAR, Tore-Supra, HT-7U, EAST, LHD, Wendelstein-7-X,...); 2) Long-pulse operation and advanced tokamak physics; 3) steady state fusion technologies; 4) Long pulse heating and current drive; 5) Particle control and power exhaust, and 6) ITER-related research and development issues. This document gathers the abstracts

  8. Capitalist Diversity and De-growth Trajectories to Steady-state Economies

    DEFF Research Database (Denmark)

    Buch-Hansen, Hubert

    2014-01-01

    Growth-critical scholarship has done much to both expose the environmentally unsustainable nature of the capitalist growth-economies of the overdeveloped part of the world and to develop an alternative vision of a degrowth transition leading to a steady-state economy. However, this scholarship...... on capitalist diversity and institutional change. On the basis of a typology of different models of capitalism, the article suggests that if de-growth transitions took place they would take different forms and lead to a variety of types of steady-state economies (SSEs). To illustrate this point, three ideal...

  9. A quaternionic map for the steady states of the Heisenberg spin-chain

    International Nuclear Information System (INIS)

    Mehta, Mitaxi P.; Dutta, Souvik; Tiwari, Shubhanshu

    2014-01-01

    We show that the steady states of the classical Heisenberg XXX spin-chain in an external magnetic field can be found by iterations of a quaternionic map. A restricted model, e.g., the xy spin-chain is known to have spatially chaotic steady states and the phase space occupied by these chaotic states is known to go through discrete changes as the field strength is varied. The same phenomenon is studied for the xxx spin-chain. It is seen that in this model the phase space volume varies smoothly with the external field.

  10. Transient and steady-state analyses of an electrically heated Topaz-II Thermionic Fuel Element

    International Nuclear Information System (INIS)

    El-Genk, M.S.; Xue, H.

    1992-01-01

    Transient and steady-state analyses of electrically heated, Thermionic Fuel Elements (TFEs) for Topaz-II space power system are performed. The calculated emitter and collector temperatures, load electric power and conversion efficiency are in good agreement with reported data. In this paper the effects or Cs pressure, thermal power input, and load resistance on the steady-state performance of the TFE are also investigated. In addition, the thermal response of the ZrH moderator during a startup transient and following a change in the thermal power input is examined

  11. A quaternionic map for the steady states of the Heisenberg spin-chain

    Energy Technology Data Exchange (ETDEWEB)

    Mehta, Mitaxi P., E-mail: mitaxi.mehta@ahduni.edu.in [IICT, Ahmedabad University, Opp. IIM, Navrangpura, Ahmedabad (India); Dutta, Souvik; Tiwari, Shubhanshu [BITS-Pilani, K.K. Birla Goa campus, Goa (India)

    2014-01-17

    We show that the steady states of the classical Heisenberg XXX spin-chain in an external magnetic field can be found by iterations of a quaternionic map. A restricted model, e.g., the xy spin-chain is known to have spatially chaotic steady states and the phase space occupied by these chaotic states is known to go through discrete changes as the field strength is varied. The same phenomenon is studied for the xxx spin-chain. It is seen that in this model the phase space volume varies smoothly with the external field.

  12. Seventh meeting of the ITER physics expert group on energetic particles, heating and steady state operations

    International Nuclear Information System (INIS)

    Gormezano, C.

    1999-01-01

    The seventh meeting of the ITER Physics Group on energetic particles, heating and steady state operation was held at CEN/Cadarache from 14 to 18 September 1999. This was the first meeting following the redefinition of the Expert Group structure and it was also the first meeting without participation of US physicists. The main topics covered were: 1. Energetic Particles, 2. Ion Cyclotron Resonance Heating, 3. Lower Hybrid Current Drive, 4. Electron Cyclotron Resonance Heating and Current Drive, 5. Neutral Beam Injection, 6. Steady-State Aspects

  13. Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers

    DEFF Research Database (Denmark)

    Christensen, Mette Marie Hougaard; Højlund, Kurt; Hother-Nielsen, Ole

    2015-01-01

    PURPOSE: The aim of the study was to determine the steady-state pharmacokinetics of metformin in healthy volunteers with different numbers of reduced-function alleles in the organic cation transporter 1 gene (OCT1). METHODS: The study was conducted as part of a randomized cross-over trial. Thirty......-four healthy volunteers with known OCT1 genotypes (12 with two wild-type alleles, 13 with one and 9 with two reduced-function alleles) were included. In one of the study periods, they were titrated to steady-state with 1 g metformin twice daily. RESULTS: Neither AUC(0-12), C(max) nor Cl(renal) were...

  14. SUPERENERGY-2: a multiassembly, steady-state computer code for LMFBR core thermal-hydraulic analysis

    Energy Technology Data Exchange (ETDEWEB)

    Basehore, K.L.; Todreas, N.E.

    1980-08-01

    Core thermal-hydraulic design and performance analyses for Liquid Metal Fast Breeder Reactors (LMFBRs) require repeated detailed multiassembly calculations to determine radial temperature profiles and subchannel outlet temperatures for various core configurations and subassembly structural analyses. At steady-state, detailed core-wide temperature profiles are required for core restraint calculations and subassembly structural analysis. In addition, sodium outlet temperatures are routinely needed for each reactor operating cycle. The SUPERENERGY-2 thermal-hydraulic code was designed specifically to meet these designer needs. It is applicable only to steady-state, forced-convection flow in LMFBR core geometries.

  15. S3C: EBT Steady-State Shooting code description and user's guide

    International Nuclear Information System (INIS)

    Downum, W.B.

    1983-09-01

    The Oak Ridge National Laboratory (ORNL) one-dimensional (1-D) Steady-State Shooting code (S3C) for ELMO Bumpy Torus (EBT) plasmas is described. Benchmark calculations finding the steady-state density and electron and ion temperature profiles for a known neutral density profile and known external energy sources are carried out. Good agreement is obtained with results from the ORNL Radially Resolved Time Dependent 1-D Transport code for an EBT-Q type reactor. The program logic is described, along with the physics models in each code block and the variable names used. Sample input and output files are listed, along with the main code

  16. Steady state detection of chemical reaction networks using a simplified analytical method.

    Directory of Open Access Journals (Sweden)

    Ivan Martínez-Forero

    Full Text Available Chemical reaction networks (CRNs are susceptible to mathematical modelling. The dynamic behavior of CRNs can be investigated by solving the polynomial equations derived from its structure. However, simple CRN give rise to non-linear polynomials that are difficult to resolve. Here we propose a procedure to locate the steady states of CRNs from a formula derived through algebraic geometry methods. We have applied this procedure to define the steady states of a classic CRN that exhibits instability, and to a model of programmed cell death.

  17. High-temperature expansion for nonequilibrium steady states in driven lattice gases.

    Science.gov (United States)

    Lefevere, Raphael; Tasaki, Hal

    2005-05-27

    We develop a controlled high-temperature expansion for nonequilibrium steady states of the driven lattice gas, the "Ising model" for nonequilibrium physics. We represent the steady state as P(eta) alpha e(-betaH(eta)-psi(eta)) and evaluate the lowest order contribution to the nonequilibrium effective interaction psi(eta). We see that, in dimensions d > or = 2, all models with nonsingular transition rates yield the same summable psi(eta), suggesting the possibility of describing the state as a Gibbs state similar to equilibrium. The models with the Metropolis rule show exceptional behavior.

  18. Studies on mass transfer in electrochemical systems

    Energy Technology Data Exchange (ETDEWEB)

    Sundstroem, L.G.

    1997-10-01

    The first part is of an introductory nature. It contains a description of the methods used, a discussion of the physics of electrochemical cells with a liquid electrolyte, and a summary of the different studies made, including both those which have been reported in papers, and those which have not. Contributions with novel aspects include (* a derivation of the electro-neutrality condition from Maxwell`s equations of electrodynamics, and **) an argument in favour of the use of mass-averaged velocity in ion transport expressions. The second part focuses on specific cases. It consists of seven research papers which give a more detailed presentation of the main studies 40 refs, 6 figs

  19. Steady state peripheral blood provides cells with functional and metabolic characteristics of real hematopoietic stem cells.

    Science.gov (United States)

    Bourdieu, Antonin; Avalon, Maryse; Lapostolle, Véronique; Ismail, Sadek; Mombled, Margaux; Debeissat, Christelle; Guérinet, Marianne; Duchez, Pascale; Chevaleyre, Jean; Vlaski-Lafarge, Marija; Villacreces, Arnaud; Praloran, Vincent; Ivanovic, Zoran; Brunet de la Grange, Philippe

    2018-01-01

    Hematopoietic stem cells (HSCs), which are located in the bone marrow, also circulate in cord and peripheral blood. Despite high availability, HSCs from steady state peripheral blood (SSPB) are little known and not used for research or cell therapy. We thus aimed to characterize and select HSCs from SSPB by a direct approach with a view to delineating their main functional and metabolic properties and the mechanisms responsible for their maintenance. We chose to work on Side Population (SP) cells which are highly enriched in HSCs in mouse, human bone marrow, and cord blood. However, no SP cells from SSBP have as yet been characterized. Here we showed that SP cells from SSPB exhibited a higher proliferative capacity and generated more clonogenic progenitors than non-SP cells in vitro. Furthermore, xenotransplantation studies on immunodeficient mice demonstrated that SP cells are up to 45 times more enriched in cells with engraftment capacity than non-SP cells. From a cell regulation point of view, we showed that SP activity depended on O 2 concentrations close to those found in HSC niches, an effect which is dependent on both hypoxia-induced factors HIF-1α and HIF-2α. Moreover SP cells displayed a reduced mitochondrial mass and, in particular, a lower mitochondrial activity compared to non-SP cells, while they exhibited a similar level of glucose incorporation. These results provided evidence that SP cells from SSPB displayed properties of very primitive cells and HSC, thus rendering them an interesting model for research and cell therapy. © 2017 Wiley Periodicals, Inc.

  20. Ultra-wideband real-time data acquisition in steady-state experiments

    International Nuclear Information System (INIS)

    Nakanishi, Hideya; Ohsuna, Masaki; Kojima, Mamoru; Nonomura, Miki; Emoto, Masahiko; Nagayama, Yoshio; Kawahata, Kazuo; Imazu, Setsuo; Okumura, Haruhiko

    2006-01-01

    The ultra-wideband real-time data acquisition (DAQ) system has started its operation at LHD steady-state experiments since 2004. It uses Compact PCI standard digitizers whose acquisition performance is continuously above 80 MB/s for each frontend, and is also capable of grabbing picture frames from high-resolution cameras. Near the end of the 8th LHD experimental period, it achieved a new world record of 84 GB/shot acquired data during about 4,000 s long-pulse discharge (no.56068). Numbers of real-time and batch DAQ were 15 and 30, respectively. To realize 80 MB/s streaming from the digitizer frontend to data storage and network clients, the acquired data are once buffered on the shared memory to be read by network streaming and data saving tasks independently. The former sends 1/N thinned stream by using a set of TCP and UDP sessions for every monitoring clients, and the latter saves raw data into a series of 10 s chunk files. Afterward, the subdivided segmental compression library 'titz' is applied in migrating them to the mass storage for enabling users to retrieve a smaller chunk of huge data. Different compression algorithms, zlib and JPEG-LS, are automatically applied for waveform picture and data, respectively. Newly made utilities and many improvements, such as acquisition status monitor, real-time waveform monitor, and 64 bit counting in digital timing system, have put the ultra-wideband acquisition system fit for practical use by entire stuff. Demonstrated technologies here could be applied for the next generation fusion experiment like ITER. (author)

  1. X-Ray Spectral Analysis of the Steady States of GRS1915+105

    Science.gov (United States)

    Peris, Charith S.; Remillard, Ronald A.; Steiner, James F.; Vrtilek, Saeqa D.; Varnière, Peggy; Rodriguez, Jerome; Pooley, Guy

    2016-05-01

    We report on the X-ray spectral behavior within the steady states of GRS1915+105. Our work is based on the full data set of the source obtained using the Proportional Counter Array (PCA) on the Rossi X-ray Timing Explorer (RXTE) and 15 GHz radio data obtained using the Ryle Telescope. The steady observations within the X-ray data set naturally separated into two regions in the color-color diagram and we refer to these regions as steady-soft and steady-hard. GRS1915+105 displays significant curvature in the coronal component in both the soft and hard data within the RXTE/PCA bandpass. A majority of the steady-soft observations displays a roughly constant inner disk radius ({R}{{in}}), while the steady-hard observations display an evolving disk truncation which is correlated to the mass accretion rate through the disk. The disk flux and coronal flux are strongly correlated in steady-hard observations and very weakly correlated in the steady-soft observations. Within the steady-hard observations, we observe two particular circumstances when there are correlations between the coronal X-ray flux and the radio flux with log slopes η ˜ 0.68+/- 0.35 and η ˜ 1.12+/- 0.13. They are consistent with the upper and lower tracks of Gallo et al. (2012), respectively. A comparison of the model parameters to the state definitions shows that almost all of the steady-soft observations match the criteria of either a thermal or steep power-law state, while a large portion of the steady-hard observations match the hard-state criteria when the disk fraction constraint is neglected.

  2. Modeling transitions in body composition: the approach to steady state for anthropometric measures and physiological functions in the Minnesota human starvation study.

    Science.gov (United States)

    Hargrove, James L; Heinz, Grete; Heinz, Otto

    2008-10-07

    This study evaluated whether the changes in several anthropometric and functional measures during caloric restriction combined with walking and treadmill exercise would fit a simple model of approach to steady state (a plateau) that can be solved using spreadsheet software (Microsoft Excel). We hypothesized that transitions in waist girth and several body compartments would fit a simple exponential model that approaches a stable steady-state. The model (an equation) was applied to outcomes reported in the Minnesota starvation experiment using Microsoft Excel's Solver function to derive rate parameters (k) and projected steady state values. However, data for most end-points were available only at t = 0, 12 and 24 weeks of caloric restriction. Therefore, we derived 2 new equations that enable model solutions to be calculated from 3 equally spaced data points. For the group of male subjects in the Minnesota study, body mass declined with a first order rate constant of about 0.079 wk-1. The fractional rate of loss of fat free mass, which includes components that remained almost constant during starvation, was 0.064 wk-1, compared to a rate of loss of fat mass of 0.103 wk-1. The rate of loss of abdominal fat, as exemplified by the change in the waist girth, was 0.213 wk-1.On average, 0.77 kg was lost per cm of waist girth. Other girths showed rates of loss between 0.085 and 0.131 wk-1. Resting energy expenditure (REE) declined at 0.131 wk-1. Changes in heart volume, hand strength, work capacity and N excretion showed rates of loss in the same range. The group of 32 subjects was close to steady state or had already reached steady state for the variables under consideration at the end of semi-starvation. When energy intake is changed to new, relatively constant levels, while physical activity is maintained, changes in several anthropometric and physiological measures can be modeled as an exponential approach to steady state using software that is widely available. The 3

  3. Steady-state acceptor fluorescence anisotropy imaging under evanescent excitation for visualisation of FRET at the plasma membrane.

    Directory of Open Access Journals (Sweden)

    Viviane Devauges

    Full Text Available We present a novel imaging system combining total internal reflection fluorescence (TIRF microscopy with measurement of steady-state acceptor fluorescence anisotropy in order to perform live cell Förster Resonance Energy Transfer (FRET imaging at the plasma membrane. We compare directly the imaging performance of fluorescence anisotropy resolved TIRF with epifluorescence illumination. The use of high numerical aperture objective for TIRF required correction for induced depolarization factors. This arrangement enabled visualisation of conformational changes of a Raichu-Cdc42 FRET biosensor by measurement of intramolecular FRET between eGFP and mRFP1. Higher activity of the probe was found at the cell plasma membrane compared to intracellularly. Imaging fluorescence anisotropy in TIRF allowed clear differentiation of the Raichu-Cdc42 biosensor from negative control mutants. Finally, inhibition of Cdc42 was imaged dynamically in live cells, where we show temporal changes of the activity of the Raichu-Cdc42 biosensor.

  4. Thermal Conductivity Change Kinetics of Ceramic Thermal Barrier Coatings Determined by the Steady-State Laser Heat Flux Technique

    Science.gov (United States)

    Zhu, Dongming; Miller, Robert A.

    2000-01-01

    A steady-state laser heat flux technique has been developed at the NASA Glenn Research Center at Lewis Field to obtain critical thermal conductivity data of ceramic thermal barrier coatings under the temperature and thermal gradients that are realistically expected to be encountered in advanced engine systems. In this study, thermal conductivity change kinetics of a plasma-sprayed, 254-mm-thick ZrO2-8 wt % Y2O3 ceramic coating were obtained at high temperatures. During the testing, the temperature gradients across the coating system were carefully measured by the surface and back pyrometers and an embedded miniature thermocouple in the substrate. The actual heat flux passing through the coating system was determined from the metal substrate temperature drop (measured by the embedded miniature thermocouple and the back pyrometer) combined with one-dimensional heat transfer models.

  5. Unification of ultra-wideband data acquisition and real-time monitoring in LHD steady-state experiments

    Energy Technology Data Exchange (ETDEWEB)

    Ohsuna, M. [National Institute for Fusion Science, 322-6 Oroshi-cho, Toki 509-5292 (Japan)]. E-mail: ohsuna@LHD.nifs.ac.jp; Nakanishi, H. [National Institute for Fusion Science, 322-6 Oroshi-cho, Toki 509-5292 (Japan); Imazu, S. [Pretech Corp., 1-19-13 Kanayama-cho, Atsuta-ku, Nagoya 456-0002 (Japan); Kojima, M. [National Institute for Fusion Science, 322-6 Oroshi-cho, Toki 509-5292 (Japan); Nonomura, M. [National Institute for Fusion Science, 322-6 Oroshi-cho, Toki 509-5292 (Japan); Emoto, M. [National Institute for Fusion Science, 322-6 Oroshi-cho, Toki 509-5292 (Japan); Nagayama, Y. [National Institute for Fusion Science, 322-6 Oroshi-cho, Toki 509-5292 (Japan); Okumura, H. [Mie University, 1577 Kurima-Machiya-cho, Tsu 514-8507 (Japan)

    2006-07-15

    To support the steady-state plasma experiments in LHD, new functions have been developed for the LABCOM data acquisition system. Using new WE7000 and PXI digitizers for continuous ultra-wideband data acquisition at 80 MB/s, the system is now able to perform data acquisition, storage, and server-to-client transfer fully in real-time. To manage the high amount of data for long-pulse experiments, the system has been modified to use 64-bit integer values for the number of samples, to segment the compressed data into multiple blocks by using the 'titz' library, and to use the JPEG-LS algorithm for compressing image data. Its merit as complete solution for the next generation of fusion experiments has been demonstrated by faultlessly recording an 84 GB shot.

  6. Comparing Non-Steady State Emissions under Start-Up and Shut-Down Operating Conditions with Steady State Emissions for Several Industrial Sectors: A Literature Review

    Directory of Open Access Journals (Sweden)

    Juwairia Obaid

    2017-02-01

    Full Text Available This study investigates the emissions of various industrial facilities under start-up, shut-down, and normal operations. The industries that have been investigated include power and/or heat generation, energy-from-waste generation, nuclear power generation, sulphuric acid production, ethylene production, petrochemical production, and waste incineration. The study investigated multiple facilities worldwide for each of these industrial categories. The different potential contaminants characteristic of each industry type have been investigated and the emissions of these contaminants under non-steady state have been compared to the steady state emissions. Where available, trends have been developed to identify the circumstances, i.e., the industrial sector and contaminant, under which the assessment and consideration of emissions from start-up and shut-down events is necessary for each industry. These trends differ by industrial sector and contaminant. For example, the study shows that sulphur dioxide (SO2 emissions should be assessed for the start-up operations of sulphuric acid production plants, but may not need to be assessed for the start-up operations of a conventional power generation facility. The trends developed as part of this research paper will help air permit applicants to effectively allocate their resources when assessing emissions related to non-steady state operations. Additionally, it will ensure that emissions are assessed for the worst-case scenario. This is especially important when emissions under start-up and shut-down operations have the potential to exceed enforceable emission limits. Thus, assessing emissions for the worst-case scenario can help in preventing the emissions from adversely impacting public health and the environment.

  7. Influence of longitudinal position on the evolution of steady-state signal in cardiac cine balanced steady-state free precession imaging.

    Science.gov (United States)

    Spear, Tyler J; Stromp, Tori A; Leung, Steve W; Vandsburger, Moriel H

    2017-11-01

    Emerging quantitative cardiac magnetic resonance imaging (CMRI) techniques use cine balanced steady-state free precession (bSSFP) to measure myocardial signal intensity and probe underlying physiological parameters. This correlation assumes that steady-state is maintained uniformly throughout the heart in space and time. To determine the effects of longitudinal cardiac motion and initial slice position on signal deviation in cine bSSFP imaging by comparing two-dimensional (2D) and three-dimensional (3D) acquisitions. Nine healthy volunteers completed cardiac MRI on a 1.5-T scanner. Short axis images were taken at six slice locations using both 2D and 3D cine bSSFP. 3D acquisitions spanned two slices above and below selected slice locations. Changes in myocardial signal intensity were measured across the cardiac cycle and compared to longitudinal shortening. For 2D cine bSSFP, 46% ± 9% of all frames and 84% ± 13% of end-diastolic frames remained within 10% of initial signal intensity. For 3D cine bSSFP the proportions increased to 87% ± 8% and 97% ± 5%. There was no correlation between longitudinal shortening and peak changes in myocardial signal. The initial slice position significantly impacted peak changes in signal intensity for 2D sequences ( P  cine bSSFP that is only restored at the center of a 3D excitation volume. During diastole, a transient steady-state is established similar to that achieved with 3D cine bSSFP regardless of slice location.

  8. Diffusion in coronas around clinopyroxene: modelling with local equilibrium and steady state, and a non-steady-state modification to account for zoned actinolite-hornblende

    Science.gov (United States)

    Ashworth, J. R.; Birdi, J. J.; Emmett, T. F.

    1992-01-01

    Retrograde coronas of Caledonian age, between clinopyroxene and plagioclase in the Jotun Nappe Complex, Norway, illustrate the effects of diffusion kinetics on mineral distributions among layers and on the compositions of hornblende-actinolite. One corona type comprises a symplectite of epidote + quartz adjacent to plagioclase, and a less well-organized intergrowth of amphibole + quartz replacing clinopyroxene. The observed mineral proportions imply an open-system reaction, but the similarity of Al/Si ratios in reactant plagioclase and product symplectite indicates approximate conservation of Al2O3 and SiO2. The largest inferred open-system flux is a loss of CaO, mostly derived from consumption of clinopyroxene. The approximate layer structure, Pl|Ep + Qtz|Hbl + Qtz|Act±Hbl + Qtz|Cpx, is modelled using the theory of steady-state diffusion-controlled growth with local equilibrium. To obtain a solution, it is necessary to use a reactant plagioclase composition which takes into account aluminous (epidote) inclusions. The results indicate that, in terms of Onsager diffusion coefficients L ii , Ca is more mobile than AL ( L CaCa/ L AlAl≳3.) (where ≳ means greater than or approximately equal to). This behaviour of Ca is comparable with that of Mg in previously studied coronas around olivine. Si is non-diffusing in the present modelling, because of silica saturation. Oxidation of some Fe2+ to Fe3+ occurs within the corona. Mg diffuses towards its source (clinopyroxene) to maintain local equilibrium. Other coronas consist of two layers, hornblende adjacent to plagioclase and zoned amphibole + quartz adjacent to clinopyroxene. In the zoned layer, actinolitic hornblende forms relict patches, separated from quartz blebs by more aluminous hornblende. A preliminary steady-state, local-equilibrium model of grain-boundary diffusion explains the formation of low-Al and high-Al layers as due to Al immobility. Zoning and replacement are qualitatively explained in terms of

  9. Progress of design studies on an LHD-type steady-state reactor

    Energy Technology Data Exchange (ETDEWEB)

    Motojima, O.; Komori, A.; Sagara, A. [National Institute for Fusion Science, Toki (Japan)

    2007-07-01

    Helical Heliotrons such as the Large Helical Device (LHD) and Stellarators (H and S systems) have a high potential to realize a current-less steady-state and stable magnetic fusion energy reactor as an alternative to the tokamak DEMO-reactor. H and S systems ideally have an intrinsic property of Q=infinite. Here it is very important to remember that the understanding of the physics of 3-D toroidal magnetic confinement system is naturally extended to tokamak systems. The physics is universal among these two types of systems and the technology is common. We present our recent results from LHD experiments and reactor studies of a next generation LHD-type DEMO Reactor called FFHR. (1) Development of 3-D superconducting (SC) coil technology Due to the successful results of the LHD construction from 1990 to 2007, and steady operation over 8 years from 1998 to 2007, more than 2,000 hrs/year at a high field of around 3 Tesla, we have a large enough data base to demonstrate that 3D coil technology has become the standard technology for a fusion energy reactor. LHD is the largest SC fusion device in the world, contributing to the development of the SC technology necessary for fusion research. The poloidal coils of LHD adopted a super critical forced flow cooling system and their dimensions are almost the same as the ITER toroidal coils. (2) Extended physics understanding of high beta, high T, high n{sub {tau}}{sub T}, and steady state operation Recent LHD experiments have demonstrated the broad and advanced capabilities of LHD as a toroidal magnetic confinement device, which are highlighted by the achievements of 5% volume averaged beta, electron and ion temperatures of 10 keV, super high density of 10E15/cc and 1 hr discharges. We plan to increase the heating power up to 35 MW, and to use deuterium gas for confinement improvement. The n{sub {tau}}{sub T} will be improved to the design nominal value of Q=0.3 within several years and ultimately would approach unity. The key

  10. Steady-state and transient performance of HVDC link based 3-level ...

    African Journals Online (AJOL)

    Administrateur

    testés par des simulations à l'aide de Matlab Simulink et SimPowerSystems toolbox. Mots clé : CCHT- convertisseur à base de source de tension- MLI - technique de contrôle - charge passive. Abstract. This paper investigates the steady-state and transient performance of high-voltage DC (HVDC) transmission systems ...

  11. Einstein's steady-state theory: an abandoned model of the cosmos

    Science.gov (United States)

    O'Raifeartaigh, Cormac; McCann, Brendan; Nahm, Werner; Mitton, Simon

    2014-09-01

    We present a translation and analysis of an unpublished manuscript by Albert Einstein in which he attempted to construct a `steady-state' model of the universe. The manuscript, which appears to have been written in early 1931, demonstrates that Einstein once explored a cosmic model in which the mean density of matter in an expanding universe is maintained constant by the continuous formation of matter from empty space. This model is very different to previously known Einsteinian models of the cosmos (both static and dynamic) but anticipates the later steady-state cosmology of Hoyle, Bondi and Gold in some ways. We find that Einstein's steady-state model contains a fundamental flaw and suggest that it was abandoned for this reason. We also suggest that he declined to explore a more sophisticated version because he found such theories rather contrived. The manuscript is of historical interest because it reveals that Einstein debated between steady-state and evolving models of the cosmos decades before a similar debate took place in the cosmological community.

  12. A partition-free approach to transient and steady-state charge currents

    DEFF Research Database (Denmark)

    Cornean, Horia; Gianesello, Céline; Zagrebnov, Valentin

    2010-01-01

    We construct a non-equilibrium steady state and calculate the corresponding current for a mesoscopic Fermi system in the partition-free setting. To this end we study a small sample coupled to a finite number of semi-infinite leads. Initially, the whole system of quasi-free fermions is in a grand-...

  13. Technical challenges in the construction of the steady-state stellarator Wendelstein 7-X

    NARCIS (Netherlands)

    Bosch, H. S.; R C Wolf,; Andreeva, T.; Baldzuhn, J.; Birus, D.; Bluhm, T.; Brauer, T.; Braune, H.; Bykov, V.; Cardella, A.; Durodie, F.; Endler, M.; Erckmann, V.; Gantenbein, G.; Hartmann, D.; Hathiramani, D.; Heimann, P.; Heinemann, B.; Hennig, C.; Hirsch, M.; Holtum, D.; Jagielski, J.; Jelonnek, J.; Kasparek, W.; Klinger, T.; Konig, R.; Kornejew, P.; Kroiss, H.; Krom, J. G.; Kuhner, G.; Laqua, H.; Laqua, H. P.; Lechte, C.; Lewerentz, M.; Maier, J.; McNeely, P.; Messiaen, A.; Michel, G.; Ongena, J.; Peacock, A.; Pedersen, T. S.; Riedl, R.; Riemann, H.; Rong, P.; Rust, N.; Schacht, J.; Schauer, F.; Schroeder, R.; Schweer, B.; Spring, A.; Stabler, A.; Thumm, M.; Turkin, Y.; Wegener, L.; Werner, A.; Zhang, D.; Zilker, M.; Akijama, T.; Alzbutas, R.; Ascasibar, E.; Balden, M.; Banduch, M.; Baylard, C.; Behr, W.; Beidler, C.; Benndorf, A.; Bergmann, T.; Biedermann, C.; Bieg, B.; Biel, W.; Borchardt, M.; Borowitz, G.; Borsuk, V.; Bozhenkov, S.; Brakel, R.; Brand, H.; Brown, T.; Brucker, B.; Burhenn, R.; Buscher, K. P.; Caldwell-Nichols, C.; Cappa, A.; Cardella, A.; Carls, A.; Carvalho, P.; Ciupinski, L.; Cole, M.; Collienne, J.; Czarnecka, A.; Czymek, G.; Dammertz, G.; Dhard, C. P.; Davydenko, V. I.; Dinklage, A.; Drevlak, M.; Drotziger, S.; Dudek, A.; Dumortier, P.; Dundulis, G.; von Eeten, P.; Egorov, K.; Estrada, T.; Faugel, H.; Fellinger, J.; Feng, Y.; Fernandes, H.; Fietz, W. H.; Figacz, W.; Fischer, F.; Fontdecaba, J.; Freund, A.; Funaba, T.; Funfgelder, H.; Galkowski, A.; Gates, D.; Giannone, L.; Regana, J. M. G.; Geiger, J.; Geissler, S.; Greuner, H.; Grahl, M.; Gross, S.; Grosman, A.; Grote, H.; Grulke, O.; R. Jaspers,; Szabo, V.

    2013-01-01

    The next step in the Wendelstein stellarator line is the large superconducting device Wendelstein 7-X, currently under construction in Greifswald, Germany. Steady-state operation is an intrinsic feature of stellarators, and one key element of the Wendelstein 7-X mission is to demonstrate

  14. Differential Cell Count of Bone Marrow Aspirates in Steady-state ...

    African Journals Online (AJOL)

    Bone marrow was aspirated from the posterior superior iliac spine. Slides were stained with MayGrünwald-Giemsa stain. Proportions of erythroid, myeloid, lymphoid and megakaryocytic cells out of 250 nucleated bone marrow cells were determined. Results: Steady state mean packed cell volume (PCV) was 0.2 ± 0.017 L/L.

  15. Analysis of steady state creep of southeastern New Mexico bedded salt

    International Nuclear Information System (INIS)

    Herrmann, W.; Wawersik, W.R.; Lauson, H.S.

    1980-03-01

    Steady state creep rates have been obtained from a large suite of existing experimental creep data relating to bedded rock salt from the Salado formation of S.E. New Mexico. Experimental conditions covered an intermediate temperature range from 22 0 C to 200 0 C, and shear stresses from 1000 psi (7 MPa) to 6000 psi (31 MPa). An expression, based on a single diffusion controlled dislocation climb mechanism, has been found to fit the observed dependence of steady state creep rate on shear stress and temperature, yielding an activation energy of 12 kcal/mole (50 kJ/mole) and a stress exponent of 4.9. Multiple regression analysis revealed a dependence on stratigraphy, but no statistically significant dependence on pressure of specimen size. No consistent dilatancy or compaction associated with steady state creep was found, although some individual specimens dilated or compacted during creep. The steady state creep data were found to agree very well with creep data for both bedded and dome salt from a variety of other locations

  16. Experimental study of vaporization effect on steady state and dynamic behavior of catalytic pellets

    NARCIS (Netherlands)

    Kulikov, A.V.; Kuzin, N.A.; Shigarov, A.B.; Kirillov, V.A.; Westerterp, K.R.; Kronberg, Alexandre E.

    2001-01-01

    The impact of the combined evaporation of the liquid phase and reaction on single catalyst pellet performance has been studied experimentally. The exothermic, catalyzed hydrogenation of α-methylstyrene (AMS) to cumene has been employed as a model reaction. Steady state and dynamic experiments have

  17. Steady State Investigations of DPF Soot Burn Rates and DPF Modeling

    DEFF Research Database (Denmark)

    Cordtz, Rasmus Lage; Ivarsson, Anders; Schramm, Jesper

    2011-01-01

    This work presents the experimental investigation of Diesel Particulate Filter (DPF) regeneration and a calibration procedure of a 1D DPF simulation model based on the commercial software AVL BOOST v. 5.1. Model constants and parameters are fitted on the basis of a number of steady state DPF expe...

  18. Steady-State Fluorescence Anisotropy to Investigate Flavonoids Binding to Proteins

    Science.gov (United States)

    Ingersoll, Christine M.; Strollo, Christen M.

    2007-01-01

    The steady-state fluorescence anisotropy is employed to study the binding of protein of a model protein, human serum albumin, to a commonly used flavonoid, quercetin. The experiment describes the thermodynamics, as well as the biochemical interactions of such binding effectively.

  19. Efficient decoding with steady-state Kalman filter in neural interface systems.

    Science.gov (United States)

    Malik, Wasim Q; Truccolo, Wilson; Brown, Emery N; Hochberg, Leigh R

    2011-02-01

    The Kalman filter is commonly used in neural interface systems to decode neural activity and estimate the desired movement kinematics. We analyze a low-complexity Kalman filter implementation in which the filter gain is approximated by its steady-state form, computed offline before real-time decoding commences. We evaluate its performance using human motor cortical spike train data obtained from an intracortical recording array as part of an ongoing pilot clinical trial. We demonstrate that the standard Kalman filter gain converges to within 95% of the steady-state filter gain in 1.5±0.5 s (mean ±s.d.). The difference in the intended movement velocity decoded by the two filters vanishes within 5 s, with a correlation coefficient of 0.99 between the two decoded velocities over the session length. We also find that the steady-state Kalman filter reduces the computational load (algorithm execution time) for decoding the firing rates of 25±3 single units by a factor of 7.0±0.9. We expect that the gain in computational efficiency will be much higher in systems with larger neural ensembles. The steady-state filter can thus provide substantial runtime efficiency at little cost in terms of estimation accuracy. This far more efficient neural decoding approach will facilitate the practical implementation of future large-dimensional, multisignal neural interface systems.

  20. Molecular control of steady-state dendritic cell maturation and immune homeostasis.

    Science.gov (United States)

    Hammer, Gianna Elena; Ma, Averil

    2013-01-01

    Dendritic cells (DCs) are specialized sentinels responsible for coordinating adaptive immunity. This function is dependent upon coupled sensitivity to environmental signs of inflammation and infection to cellular maturation-the programmed alteration of DC phenotype and function to enhance immune cell activation. Although DCs are thus well equipped to respond to pathogens, maturation triggers are not unique to infection. Given that immune cells are exquisitely sensitive to the biological functions of DCs, we now appreciate that multiple layers of suppression are required to restrict the environmental sensitivity, cellular maturation, and even life span of DCs to prevent aberrant immune activation during the steady state. At the same time, steady-state DCs are not quiescent but rather perform key functions that support homeostasis of numerous cell types. Here we review these functions and molecular mechanisms of suppression that control steady-state DC maturation. Corruption of these steady-state operatives has diverse immunological consequences and pinpoints DCs as potent drivers of autoimmune and inflammatory disease.

  1. STEADY STATE FLAMMABLE GAS RELEASE RATE CALCULATION & LOWER FLAMMABILITY LEVEL EVALUATION FOR HANFORD TANK WASTE

    Energy Technology Data Exchange (ETDEWEB)

    HU, T.A.

    2005-10-27

    Assess the steady-state flammability level at normal and off-normal ventilation conditions. The hydrogen generation rate was calculated for 177 tanks using the rate equation model. Flammability calculations based on hydrogen, ammonia, and methane were performed for 177 tanks for various scenarios.

  2. STEADY STATE FLAMMABLE GAS RELEASE RATE CALCULATION AND LOWER FLAMMABILITY LEVEL EVALUATION FOR HANFORD TANK WASTE

    Energy Technology Data Exchange (ETDEWEB)

    HU TA

    2009-10-26

    Assess the steady-state flammability level at normal and off-normal ventilation conditions. The hydrogen generation rate was calculated for 177 tanks using the rate equation model. Flammability calculations based on hydrogen, ammonia, and methane were performed for 177 tanks for various scenarios.

  3. Radioactivity computation of steady-state and pulsed fusion reactors operation

    International Nuclear Information System (INIS)

    Attaya, H.

    1994-06-01

    Different mathematical methods are used to calculate the nuclear transmutation in steady-state and pulsed neutron irradiation. These methods are the Schuer decomposition, the eigenvector decomposition, and the Pade approximation of the matrix exponential function. In the case of the linear decay chain approximation, a simple algorithm is used to evaluate the transition matrices

  4. Isoforms of human cytochrome-c oxidase. Subunit composition and steady-state kinetic properties

    NARCIS (Netherlands)

    van Kuilenburg, A. B.; Dekker, H. L.; van den Bogert, C.; Nieboer, P.; van Gelder, B. F.; Muijsers, A. O.

    1991-01-01

    The subunit pattern and the steady-state kinetics of cytochrome-c oxidase from human heart, muscle, kidney and liver were investigated. Polyacrylamide gel electrophoresis of immunopurified cytochrome-c oxidase preparations suggest that isoforms of subunit VIa exist, which show differences in

  5. Applications of mixed Petrov-Galerkin finite element methods to transient and steady state creep analysis

    International Nuclear Information System (INIS)

    Guerreiro, J.N.C.; Loula, A.F.D.

    1988-12-01

    The mixed Petrov-Galerkin finite element formulation is applied to transiente and steady state creep problems. Numerical analysis has shown additional stability of this method compared to classical Galerkin formulations. The accuracy of the new formulation is confirmed in some representative examples of two dimensional and axisymmetric problems. (author) [pt

  6. System and method for generating steady state confining current for a toroidal plasma fusion reactor

    International Nuclear Information System (INIS)

    Bers, A.

    1981-01-01

    A system for generating steady state confining current for a toroidal plasma fusion reactor providing steady-state generation of the thermonuclear power. A dense, hot toroidal plasma is initially prepared with a confining magnetic field with toroidal and poloidal components. Continuous wave rf energy is injected into said plasma to estalish a spectrum of traveling waves in the plasma, where the traveling waves have momentum components substantially either all parallel, or all anti-parallel to the confining magnetic field. The injected rf energy is phased to couple to said traveling waves with both a phase velocity component and a wave momentum component in the direction of the plasma traveling wave components. The injected rf energy has a predetermined spectrum selected so that said traveling waves couple to plasma electrons having velocities in a predetermined range delta . The velocities in the range are substantially greater than the thermal electron velocity of the plasma. In addition, the range is sufficiently broad to produce a raised plateau having width delta in the plasma electron velocity distribution so that the plateau electrons provide steady-state current to generate a poloidal magnetic field component sufficient for confining the plasma. In steady state operation of the fusion reactor, the fusion power density in the plasma exceeds the power dissipated inthe plasma

  7. Analysis of Plasticity, Fracture and Friction in Steady State Plate Cutting

    DEFF Research Database (Denmark)

    Simonsen, Bo Cerup; Wierzbicki, Tomasz

    1996-01-01

    A closed form solution to the problem of steady state wedge cutting through a ductile metal plate is presented. The considered problem is an idealization of a ship bottom raking process, i.e. a continuous cutting damage of a ship bottom by a hard knife-like rock in a grounding event. A new...

  8. Real-time dynamic hydraulic model for water distribution networks: steady state modelling

    CSIR Research Space (South Africa)

    Osman, Mohammad S

    2016-09-01

    Full Text Available steady state hydraulic model that will be used within a real-time dynamic hydraulic model (DHM). The Council for Scientific and Industrial Research (CSIR) water distribution network (WDN) is used as a pilot study for this purpose. A hydraulic analysis...

  9. The total quasi-steady-state approximation for fully competitive enzyme reactions

    DEFF Research Database (Denmark)

    Pedersen, Morten Gram; Bersani, A.M.; Bersani, E.

    2007-01-01

    The validity of the Michaelis-Menten-Briggs-Haldane approximation for single enzyme reactions has recently been improved by the formalism of the total quasi-steady-state approximation. This approach is here extended to fully competitive systems, and a criterion for its validity is provided. We show...

  10. Reliable and Efficient Procedure for Steady-State Analysis of Nonautonomous and Autonomous Systems

    Directory of Open Access Journals (Sweden)

    J. Dobes

    2012-04-01

    Full Text Available The majority of contemporary design tools do not still contain steady-state algorithms, especially for the autonomous systems. This is mainly caused by insufficient accuracy of the algorithm for numerical integration, but also by unreliable steady-state algorithms themselves. Therefore, in the paper, a very stable and efficient procedure for the numerical integration of nonlinear differential-algebraic systems is defined first. Afterwards, two improved methods are defined for finding the steady state, which use this integration algorithm in their iteration loops. The first is based on the idea of extrapolation, and the second utilizes nonstandard time-domain sensitivity analysis. The two steady-state algorithms are compared by analyses of a rectifier and a C-class amplifier, and the extrapolation algorithm is primarily selected as a more reliable alternative. Finally, the method based on the extrapolation naturally cooperating with the algorithm for solving the differential-algebraic systems is thoroughly tested on various electronic circuits: Van der Pol and Colpitts oscillators, fragment of a large bipolar logical circuit, feedback and distributed microwave oscillators, and power amplifier. The results confirm that the extrapolation method is faster than a classical plain numerical integration, especially for larger circuits with complicated transients.

  11. Rate sensitivity of mixed mode interface toughness of dissimilar metallic materials: Studied at steady state

    DEFF Research Database (Denmark)

    Nielsen, Kim Lau; Niordson, Christian Frithiof

    2012-01-01

    the SSV model [Suo, Z., Shih, C., Varias, A., 1993. A theory for cleavage cracking in the presence of plastic flow. Acta Metall. Mater. 41, 1551–1557] embedded in a steady state finite element formulation, here assuming plane strain conditions and small-scale yielding. Results are presented for a wide...

  12. Spectrally selective imaging with wideband balanced steady-state free precession MRI.

    Science.gov (United States)

    Çukur, Tolga

    2016-03-01

    Unwanted, bright fat signals in balanced steady-state free precession sequences are commonly suppressed using spectral shaping. Here, a new spectral-shaping method is proposed to significantly improve the uniformity of stopband suppression without compromising the level of passband signals. The proposed method combines binomial-pattern excitation pulses with a wideband balanced steady-state free precession sequence kernel. It thereby increases the frequency separation between the centers of pass and stopbands by π radians, enabling improved water-fat contrast. Simulations were performed to find the optimal flip angles and subpulse spacing for the binomial pulses that maximize contrast and signal efficiency. Comparisons with a conventional binomial balanced steady-state free precession sequence were performed in simulations as well as phantom and in vivo experiments at 1.5 T and 3 T. Enhanced fat suppression is demonstrated in vivo with an average improvement of 58% in blood-fat and 68% in muscle-fat contrast (P steady-state free precession method is a promising candidate for spectrally selective imaging with enhanced reliability against field inhomogeneities. © 2015 Wiley Periodicals, Inc.

  13. Steady state drift vortices in plasmas with shear flow in equilibrium

    DEFF Research Database (Denmark)

    Chakrabarti, N.

    1999-01-01

    The Hasegawa-Mima equation in the presence of sheared poloidal flow is solved for two-dimensional steady state vortex. It is shown that when the phase velocity of the vortex is the same as the diamagnetic drift velocity, an exact solution in the form of counter-rotating vortices may appear...

  14. Mechanistic assessment of hillslope transpiration controls of diel subsurface flow: a steady-state irrigation approach

    Science.gov (United States)

    H.R. Barnard; C.B. Graham; W.J. van Verseveld; J.R. Brooks; B.J. Bond; J.J. McDonnell

    2010-01-01

    Mechanistic assessment of how transpiration influences subsurface flow is necessary to advance understanding of catchment hydrology. We conducted a 24-day, steady-state irrigation experiment to quantify the relationships among soil moisture, transpiration and hillslope subsurface flow. Our objectives were to: (1) examine the time lag between maximum transpiration and...

  15. A Steady State Visually Evoked Potential Investigation of Memory and Ageing

    Science.gov (United States)

    Macpherson, Helen; Pipingas, Andrew; Silberstein, Richard

    2009-01-01

    Old age is generally accompanied by a decline in memory performance. Specifically, neuroimaging and electrophysiological studies have revealed that there are age-related changes in the neural correlates of episodic and working memory. This study investigated age-associated changes in the steady state visually evoked potential (SSVEP) amplitude and…

  16. Molecular Control of Steady-State Dendritic Cell Maturation and Immune Homeostasis

    Science.gov (United States)

    Hammer, Gianna Elena; Ma, Averil

    2014-01-01

    Dendritic cells (DCs) are specialized sentinels responsible for coordinating adaptive immunity. This function is dependent upon coupled sensitivity to environmental signs of inflammation and infection to cellular maturation—the programmed alteration of DC phenotype and function to enhance immune cell activation. Although DCs are thus well equipped to respond to pathogens, maturation triggers are not unique to infection. Given that immune cells are exquisitely sensitive to the biological functions of DCs, we now appreciate that multiple layers of suppression are required to restrict the environmental sensitivity, cellular maturation, and even life span of DCs to prevent aberrant immune activation during the steady state. At the same time, steady-state DCs are not quiescent but rather perform key functions that support homeostasis of numerous cell types. Here we review these functions and molecular mechanisms of suppression that control steady-state DC maturation. Corruption of these steady-state operatives has diverse immunological consequences and pinpoints DCs as potent drivers of autoimmune and inflammatory disease. PMID:23330953

  17. Current Pressure Transducer Application of Model-based Prognostics Using Steady State Conditions

    Science.gov (United States)

    Teubert, Christopher; Daigle, Matthew J.

    2014-01-01

    Prognostics is the process of predicting a system's future states, health degradation/wear, and remaining useful life (RUL). This information plays an important role in preventing failure, reducing downtime, scheduling maintenance, and improving system utility. Prognostics relies heavily on wear estimation. In some components, the sensors used to estimate wear may not be fast enough to capture brief transient states that are indicative of wear. For this reason it is beneficial to be capable of detecting and estimating the extent of component wear using steady-state measurements. This paper details a method for estimating component wear using steady-state measurements, describes how this is used to predict future states, and presents a case study of a current/pressure (I/P) Transducer. I/P Transducer nominal and off-nominal behaviors are characterized using a physics-based model, and validated against expected and observed component behavior. This model is used to map observed steady-state responses to corresponding fault parameter values in the form of a lookup table. This method was chosen because of its fast, efficient nature, and its ability to be applied to both linear and non-linear systems. Using measurements of the steady state output, and the lookup table, wear is estimated. A regression is used to estimate the wear propagation parameter and characterize the damage progression function, which are used to predict future states and the remaining useful life of the system.

  18. Steady-state choice between four alternatives obeys the constant-ratio rule.

    Science.gov (United States)

    Bensemann, Joshua; Lobb, Brenda; Podlesnik, Christopher A; Elliffe, Douglas

    2015-07-01

    We investigated why violations to the constant-ratio rule, an assumption of the generalized matching law, occur in procedures that arrange frequent changes to reinforcer ratios. Our investigation produced steady-state data and compared them with data from equivalent, frequently changing procedures. Six pigeons responded in a four-alternative concurrent-schedule experiment with an arranged reinforcer-rate ratio of 27:9:3:1. The same four variable-interval schedules were used in every condition, for 50 sessions, and the physical location of each schedule was changed across conditions. The experiment was a steady-state version of a frequently changing procedure in which the locations of four VI schedules were changed every 10 reinforcers. We found that subjects' responding was consistent with the constant-ratio rule in the steady-state procedure. Additionally, local analyses showed that preference after reinforcement was towards the alternative that was likely to produce the next reinforcer, instead of being towards the just-reinforced alternative as in frequently changing procedures. This suggests that the effect of a reinforcer on preference is fundamentally different in rapidly changing and steady-state environments. Comparing this finding to the existing literature suggests that choice is more influenced by reinforcer-generated signals when the reinforcement contingencies often change. © Society for the Experimental Analysis of Behavior.

  19. Quantifying biases in non-steady state chamber measurements of soil-atmosphere gas exchange

    Science.gov (United States)

    Limitations of non-steady state (NSS) chamber methods for determining soil-to-atmosphere trace gas exchange rates have been recognized for several decades. Of these limitations, the so-called “chamber effect” is one of the most challenging to overcome. The chamber effect can be defined as the inhere...

  20. Theoretical comparison of advanced methods for calculating nitrous oxide fluxes using non-steady state chambers

    Science.gov (United States)

    Several flux-calculation (FC) schemes are available for determining soil-to-atmosphere emissions of nitrous oxide (N2O) and other trace gases using data from non-steady-state flux chambers. Recently developed methods claim to provide more accuracy in estimating the true pre-deployment flux (f0) comp...

  1. Differential contribution of monocytes to heart macrophages in steady-state and after myocardial infarction

    NARCIS (Netherlands)

    Heidt, Timo; Courties, Gabriel; Dutta, Partha; Sager, Hendrik B.; Sebas, Matt; Iwamoto, Yoshiko; Sun, Yuan; Da Silva, Nicolas; Panizzi, Peter; van der Lahn, Anja M.; Swirski, Filip K.; Weissleder, Ralph; Nahrendorf, Matthias

    2014-01-01

    Macrophages populate the steady-state myocardium. Previously, all macrophages were thought to arise from monocytes; however, it emerged that, in several organs, tissue-resident macrophages may self-maintain through local proliferation. Our aim was to study the contribution of monocytes to

  2. Transient and Steady-State Responses of an Asymmetric Nonlinear Oscillator

    Directory of Open Access Journals (Sweden)

    Alex Elías-Zúñiga

    2013-01-01

    oscillator that describes the motion of a damped, forced system supported symmetrically by simple shear springs on a smooth inclined bearing surface. We also use the percentage overshoot value to study the influence of damping and nonlinearity on the transient and steady-state oscillatory amplitudes.

  3. A quasi-steady state shrinking core model of "whole tree" combustion

    African Journals Online (AJOL)

    Remember me, or Register. DOWNLOAD FULL TEXT Open Access DOWNLOAD FULL TEXT Subscription or Fee Access. A quasi-steady state shrinking core model of "whole tree" combustion. A. Ouédraogo, JC Mulligan, JG Cleland. Abstract. (J. de la Recherche Scientifique de l'Université de Lomé, 2000, 4(2): 199-208) ...

  4. Incorporation of wind generation to the Mexican power grid: Steady state analysis

    Energy Technology Data Exchange (ETDEWEB)

    Tovar, J.H.; Guardado, J.L.; Cisneros, F. [Inst. Tecnologico de Morelia (Mexico); Cadenas, R.; Lopez, S. [Comision Federal de Electricidad, Morelia (Mexico)

    1997-09-01

    This paper describes a steady state analysis related with the incorporation of large amounts of eolic generation into the Mexican power system. An equivalent node is used to represent individual eolic generators in the wind farm. Possible overloads, losses, voltage and reactive profiles and estimated severe contingencies are analyzed. Finally, the conclusions of this study are presented.

  5. System and method for generating steady state confining current for a toroidal plasma fusion reactor

    International Nuclear Information System (INIS)

    Fisch, N.J.

    1981-01-01

    A system for generating steady state confining current for a toroidal plasma fusion reactor providing steady-state generation of the thermonuclear power. A dense, hot toroidal plasma is initially prepared with a confining magnetic field with toroidal and poloidal components. Continuous wave rf energy is injected into said plasma to establish a spectrum of traveling waves in the plasma, where the traveling waves have momentum components substantially either all parallel, or all anti-parallel to the confining magnetic field. The injected rf energy is phased to couple to said traveling waves with both a phase velocity component and a wave momentum component in the direction of the plasma traveling wave components. The injected rf energy has a predetermined spectrum selected so that said traveling waves couple to plasma electrons having velocities in a predetermined range delta . The velocities in the range are substantially greater than the thermal electron velocity of the plasma. In addition, the range is sufficiently broad to produce a raised plateau having width delta in the plasma electron velocity distribution so that the plateau electrons provide steady-state current to generate a poloidal magnetic field component sufficient for confining the plasma. In steady state operation of the fusion reactor, the fusion power density in the plasma exceeds the power dissipated in the plasma

  6. Single-dose and steady-state pharmacokinetics of diltiazem administered in two different tablet formulations

    DEFF Research Database (Denmark)

    Christrup, Lona Louring; Bonde, J; Rasmussen, S N

    1992-01-01

    Single-dose and steady state pharmacokinetics of diltiazem administered in two different oral formulations were assessed with particular reference to rate and extent of absorption. Following single dose administration a significant difference in tmax was observed (2.9 +/- 1.9 and 6.8 +/- 2.6 hr r...

  7. Transient and steady state photoelectronic analysis in TlInSe{sub 2} crystals

    Energy Technology Data Exchange (ETDEWEB)

    Qasrawi, A.F., E-mail: aqasrawi@atilim.edu.tr [Group of Physics, Faculty of Engineering, Atilim University, 06836 Ankara (Turkey); Department of Physics, Arab-American University, Jenin, West Bank, Palestine (Country Unknown); Gasanly, N.M. [Department of Physics, Middle East Technical University, 06531 Ankara (Turkey)

    2011-08-15

    Highlights: {yields} The steady state and time dependent photoconductivity kinetics of the TlInSe{sub 2} crystals are investigated in the temperature region of 100-350 K. {yields} The photocurrent of the sample exhibited linear, sublinear, and supralinear recombination mechanisms, at, above and below 160 K, respectively. {yields} Steady state photoconductivity revealed two recombination centres located at 234 and 94 meV. {yields} The transient photoconductivity is limited by a trapping center located at 173 meV. {yields} The capture coefficient of the trap for holes was determined as 3.11 x 10{sup -22} cm{sup -2}. -- Abstract: The temperature and illumination effects on the transient and steady state photoconductivities of TlInSe{sub 2} crystals have been studied. Namely, two recombination centres located at 234 and at 94 meV and one trap center located at 173 meV were determined from the temperature-dependent steady state and transient photoconductivities, respectively. The illumination dependence of photoconductivity indicated the domination of sublinear and supralinear recombination mechanisms above and below 160 K, respectively. The change in the recombination mechanism is attributed to the exchange of roles between the linear recombination at the surface and trapping centres in the crystal, which become dominant as temperature decreases. The transient photoconductivity measurement allowed the determination of the capture coefficient of traps for holes as 3.11 x 10{sup -22} cm{sup -2}.

  8. Steady-state, elastic-plastic growth of slanted cracks in symmetrically loaded plates

    DEFF Research Database (Denmark)

    Nielsen, Kim Lau; Hutchinson, J. W.

    2017-01-01

    of the plate, the problem would be mode I, but due to the slant the local conditions along the crack front are a combination of mode I and mode III. A three-dimensional formulation for steady-state crack propagation is employed to generate distributions of effective stress, stress triaxiality and Lode...

  9. Quasi-steady state thermal performances of a solar air heater with ...

    African Journals Online (AJOL)

    Quasi-steady state thermal performance of a solar air heater with a combined absorber is studied. The whole energy balance equations related to the system were articulated as a linear system of temperature equations. Solutions to this linear system were assessed from program based on an iterative process. The mean ...

  10. Coagulation profile of children with sickle cell anemia in steady state ...

    African Journals Online (AJOL)

    Background: Sickle cell anemia is associated with a hypercoagulable state that may lead to alterations in a coagulation profile. Measurements of coagulation factors are known to have some predictive value for clinical outcome. Objectives: To determine the coagulation profile of children with SCA in steady state and crisis ...

  11. Controlling Unknown Saddle Type Steady States of Dynamical Systems with Latency in the Feedback Loop

    DEFF Research Database (Denmark)

    Tamasevicius, Arunas; Bumeliene, Skaidra; Tamaseviciute, Elena

    2009-01-01

    We suggest an adaptive control technique for stabilizing saddle type unstable steady states of dynamical systems. The controller is composed of an unstable and a stable high-pass filters operating in parallel. The mathematical model is considered analytically and numerically. The conjoint...

  12. Effect of stacking fault energy on steady-state creep rate of face ...

    African Journals Online (AJOL)

    Continuum elastic theory was used to establish the relationships between the force of interaction required to constrict dislocation partials, energy of constriction and climb velocity of the constricted thermal jogs, in order to examine the effect of stacking fault energy (SFE) on steady state creep rate of face centered cubic ...

  13. Steady-state transport equation resolution by particle methods, and numerical results

    International Nuclear Information System (INIS)

    Mercier, B.

    1985-10-01

    A method to solve steady-state transport equation has been given. Principles of the method are given. The method is studied in two different cases; estimations given by the theory are compared to numerical results. Results got in 1-D (spherical geometry) and in 2-D (axisymmetric geometry) are given [fr

  14. RESEARCH OF THE MASS TRANSFER AT MEMBRANE CLEANING OF BIOGAZ

    Directory of Open Access Journals (Sweden)

    Marat SATAYEV

    2015-04-01

    Full Text Available Everyone has long known the benefits and effectiveness of biogas. Particularly, getting biogas from the agricultural waste is very promising. But, the question is if we can use such a useful and effective biogas at 100%. Today, we use only a half of the benefit, because to get the biogas we spend more energy than we get. In this regard, the work on the study of the biogas development is extremely important. The study of the biogas formation requires numerous experiments. This article analyzes the biogas mass transfer with the membrane purification and identification of the of mass transfer mechanisms through the membrane pores.

  15. Mass transfer apparatus and method for separation of gases

    Energy Technology Data Exchange (ETDEWEB)

    Blount, Gerald C.; Gorensek, Maximilian Boris; Hamm, Luther L.

    2018-01-16

    A process and apparatus for separating components of a source gas is provided in which more soluble components of the source gas are dissolved in an aqueous solvent at high pressure. The system can utilize hydrostatic pressure to increase solubility of the components of the source gas. The apparatus includes gas recycle throughout multiple mass transfer stages to improve mass transfer of the targeted components from the liquid to gas phase. Separated components can be recovered for use in a value added application or can be processed for long-term storage, for instance in an underwater reservoir.

  16. Mixed convective heat transfer from a vertical plate embedded in a ...

    Indian Academy of Sciences (India)

    Abstract. The effect of melting and solute dispersion on heat and mass transfer in non-Darcy fluid flow over a vertical surface has been studied numerically in the present article. The flow is assumed to be laminar and steady state. Using similarity transformations, the governing boundary layer equations are transformed into ...

  17. Heat and mass transfer enhancement in absorbing processes

    International Nuclear Information System (INIS)

    Hijikata, Kunio; Lee, S.K.

    1993-01-01

    The key to improving the performance of absorption-type heat machines lies in the enhancement of the mass transfer of the vapor into the absorbant solution, since the mass diffusivity in the solution is very small compared to the thermal diffusivity. The absorption process is influenced by many factors including physical properties of the fluids, the flow pattern and others, especially the velocity profile near the interface is the most important. From these stand points, the heat and mass transfer in the absorption was investigated by following three steps. First, an augmentation of the absorption to a liquid film flowing in groove was theoretically investigated, in which the interface between the vapor and liquid film is cooled by the grooved surfaces. Secondly, systematical experiments were carried out on several factors that affect the absorption process, which were the cooling wall temperature, the inlet solution subcooling, and the fin configuration. Finally, a numerical study of the heat and mass transfer enhancement due to flow agitation by the periodically grooved channel was conducted. That flow realized by fabricating ridges on the fin surface. A secondary flow due to these ridges is expected to enhance the heat and mass transfer. These results were compared with experimental ones. (orig.)

  18. Fluctuation Theorem, Nonequilibrium Steady States and MacLennan-Zubarev Ensembles of $L^1$-Asymptotic Abelian C$^*$ Dynamical Systems

    CERN Document Server

    Tasaki, S

    2002-01-01

    For an infinitely extended system divisable into a finite subsystem and several reservoirs, the time evolution of initial states, where the reservoirs are in equilibrium with different temperatures and chemical potentials, is studied. Under the assumption that the time evolution is $L^1$-asymptotic abelian, (i) \\ the existence of the steady states, (ii) \\ the division independence of the steady states and their relative entropy production, and (iii) \\ the stability of steady states against local perturbations are shown. The explicit expression of the relative entropy production and a KMS characterization of the steady states are given. Without the $L^1$-asymptotic abelian property, a noncommutative analog to the fluctuation theorem is derived as well.

  19. Existence and instability of steady states for a triangular cross-diffusion system: A computer-assisted proof

    Science.gov (United States)

    Breden, Maxime; Castelli, Roberto

    2018-05-01

    In this paper, we present and apply a computer-assisted method to study steady states of a triangular cross-diffusion system. Our approach consist in an a posteriori validation procedure, that is based on using a fixed point argument around a numerically computed solution, in the spirit of the Newton-Kantorovich theorem. It allows to prove the existence of various non homogeneous steady states for different parameter values. In some situations, we obtain as many as 13 coexisting steady states. We also apply the a posteriori validation procedure to study the linear stability of the obtained steady states, proving that many of them are in fact unstable.

  20. A semi-analytical solution to accelerate spin-up of a coupled carbon and nitrogen land model to steady state

    Directory of Open Access Journals (Sweden)

    J. Y. Xia

    2012-10-01

    Full Text Available The spin-up of land models to steady state of coupled carbon–nitrogen processes is computationally so costly that it becomes a bottleneck issue for global analysis. In this study, we introduced a semi-analytical solution (SAS for the spin-up issue. SAS is fundamentally based on the analytic solution to a set of equations that describe carbon transfers within ecosystems over time. SAS is implemented by three steps: (1 having an initial spin-up with prior pool-size values until net primary productivity (NPP reaches stabilization, (2 calculating quasi-steady-state pool sizes by letting fluxes of the equations equal zero, and (3 having a final spin-up to meet the criterion of steady state. Step 2 is enabled by averaged time-varying variables over one period of repeated driving forcings. SAS was applied to both site-level and global scale spin-up of the Australian Community Atmosphere Biosphere Land Exchange (CABLE model. For the carbon-cycle-only simulations, SAS saved 95.7% and 92.4% of computational time for site-level and global spin-up, respectively, in comparison with the traditional method (a long-term iterative simulation to achieve the steady states of variables. For the carbon–nitrogen coupled simulations, SAS reduced computational cost by 84.5% and 86.6% for site-level and global spin-up, respectively. The estimated steady-state pool sizes represent the ecosystem carbon storage capacity, which was 12.1 kg C m−2 with the coupled carbon–nitrogen global model, 14.6% lower than that with the carbon-only model. The nitrogen down-regulation in modeled carbon storage is partly due to the 4.6% decrease in carbon influx (i.e., net primary productivity and partly due to the 10.5% reduction in residence times. This steady-state analysis accelerated by the SAS method can facilitate comparative studies of structural differences in determining the ecosystem carbon storage capacity among biogeochemical models. Overall, the

  1. A pre-steady state and steady state kinetic analysis of the N-ribosyl hydrolase activity of hCD157.

    Science.gov (United States)

    Preugschat, Frank; Carter, Luke H; Boros, Eric E; Porter, David J T; Stewart, Eugene L; Shewchuk, Lisa M

    2014-12-15

    hCD157 catalyzes the hydrolysis of nicotinamide riboside (NR) and nicotinic acid riboside (NAR). The release of nicotinamide or nicotinic acid from NR or NAR was confirmed by spectrophotometric, HPLC and NMR analyses. hCD157 is inactivated by a mechanism-based inhibitor, 2'-deoxy-2'-fluoro-nicotinamide arabinoside (fNR). Modification of the enzyme during the catalytic cycle by NR, NAR, or fNR increased the intrinsic protein fluorescence by approximately 50%. Pre-steady state and steady state data were used to derive a minimal kinetic scheme for the hydrolysis of NR. After initial complex formation a reversible step (360 and 30s(-1)) is followed by a slow irreversible step (0.1s(-1)) that defined the rate limiting step, or kcat. The calculated KMapp value for NR in the hydrolytic reaction is 6nM. The values of the kinetic constants suggest that one biological function of cell-surface hCD157 is to bind and slowly hydrolyze NR, possibly converting it to a ligand-activated receptor. Differences in substrate preference between hCD157 and hCD38 were rationalized through a comparison of the crystal structures of the two proteins. This comparison identified several residues in hCD157 (F108 and F173) that can potentially hinder the binding of dinucleotide substrates (NAD+). Copyright © 2014 Elsevier Inc. All rights reserved.

  2. Geoelectrical Measurement of Multi-Scale Mass Transfer Parameters

    Energy Technology Data Exchange (ETDEWEB)

    Day-Lewis, Frederick; Singha, Kamini; Haggerty, Roy; Johnson, Tim; Binley, Andrew; Lane, John

    2014-01-16

    Mass transfer affects contaminant transport and is thought to control the efficiency of aquifer remediation at a number of sites within the Department of Energy (DOE) complex. An improved understanding of mass transfer is critical to meeting the enormous scientific and engineering challenges currently facing DOE. Informed design of site remedies and long-term stewardship of radionuclide-contaminated sites will require new cost-effective laboratory and field techniques to measure the parameters controlling mass transfer spatially and across a range of scales. In this project, we sought to capitalize on the geophysical signatures of mass transfer. Previous numerical modeling and pilot-scale field experiments suggested that mass transfer produces a geoelectrical signature—a hysteretic relation between sampled (mobile-domain) fluid conductivity and bulk (mobile + immobile) conductivity—over a range of scales relevant to aquifer remediation. In this work, we investigated the geoelectrical signature of mass transfer during tracer transport in a series of controlled experiments to determine the operation of controlling parameters, and also investigated the use of complex-resistivity (CR) as a means of quantifying mass transfer parameters in situ without tracer experiments. In an add-on component to our grant, we additionally considered nuclear magnetic resonance (NMR) to help parse mobile from immobile porosities. Including the NMR component, our revised study objectives were to: 1. Develop and demonstrate geophysical approaches to measure mass-transfer parameters spatially and over a range of scales, including the combination of electrical resistivity monitoring, tracer tests, complex resistivity, nuclear magnetic resonance, and materials characterization; and 2. Provide mass-transfer estimates for improved understanding of contaminant fate and transport at DOE sites, such as uranium transport at the Hanford 300 Area. To achieve our objectives, we implemented a 3

  3. Heat and mass transfer enforcement of vibrating fluidized bed

    Science.gov (United States)

    Chu, Zhide; Yang, Junhong; Li, Xuhui; Song, Yang

    1994-12-01

    This paper briefly introduces the development of vibrating fluidized bed at home and abroad, elaborates the vibration properties of vibrating fluidized bed, the fluidizing velocity and pressure drop of the bed layer. It also deduces the non-steady state drying dynamic equations of vibrating fluidized bed, analyzes main factors which influence the drying rate and inquires into drying rules of fixed bed and vibrating fluidized bed.

  4. Systematic evaluations regarding interparticular mass transfer in spheronization.

    Science.gov (United States)

    Koester, Martin; Willemsen, Emilie; Krueger, Cornelia; Thommes, Markus

    2012-07-15

    Pellets are frequently used in pharmaceutical applications. The extrusion-spheronization process is a well-established technique used to produce pellets of a spherical shape and narrow size distribution. In this process, cylindrical extrudates are transformed into spherical pellets by spheronization. Most established mechanisms consider only breakage and deformation to explain pellet formation. An interaction between the rounding extrudates via adhesion of fine particles was not considered for many years. This study deals with the evolution of pellet properties over time during the spheronization process in order to quantify the influence of pellet interactions on their properties. Therefore the most important pelletization aids (MCCI, MCCII and κ-carrageenan) were investigated using acetaminophen as a model drug and lactose as a filler. In the first seconds of the spheronization process, a high fine fraction was seen which decreased during the process. Simultaneously, the material transferred between the pellets increased. However the fine fraction is not high enough to explain the mass transfer; therefore a direct transfer between the pellets was assumed. The pelletization aid has a huge influence on the amount of mass transferred. Whereas κ-carrageenan leads to a quite low mass transfer of 15%, MCCI and MCCII show higher values up to 25%. Copyright © 2012 Elsevier B.V. All rights reserved.

  5. Mass transfer in rolling rotary kilns : a novel approach

    NARCIS (Netherlands)

    Heydenrych, M.D.; Greeff, P.; Heesink, A. Bert M.; Versteeg, G.F.

    2002-01-01

    A novel approach to modeling mass transfer in rotary kilns or rotating cylinders is explored. The movement of gas in the interparticle voids in the bed of the kiln is considered, where particles move concentrically with the geometry of the kiln and gas is entrained by these particles. The approach

  6. Mass transfer in rolling rotary kilns: a novel approach

    NARCIS (Netherlands)

    Heydenrych, M.D.; Greeff, P.; Heesink, Albertus B.M.; Versteeg, Geert

    2002-01-01

    A novel approach to modeling mass transfer in rotary kilns or rotating cylinders is explored. The movement of gas in the interparticle voids in the bed of the kiln is considered, where particles move concentrically with the geometry of the kiln and gas is entrained by these particles. The approach

  7. Heat and mass transfer during baking: product quality aspects

    NARCIS (Netherlands)

    Asselman, A.; Straten, van G.; Hadiyanto, H.; Boom, R.M.; Esveld, D.C.; Boxtel, van A.J.B.

    2005-01-01

    Abstract Most food product qualities are developed during heating processes. Therefore the internal heating and mass transfer of water are important aspects in food processing. Heating of food products is mostly induced by convection heating. However, the number applications of convective heating in

  8. Modelling toluene oxidation : Incorporation of mass transfer phenomena

    NARCIS (Netherlands)

    Hoorn, J.A.A.; van Soolingen, J.; Versteeg, G. F.

    The kinetics of the oxidation of toluene have been studied in close interaction with the gas-liquid mass transfer occurring in the reactor. Kinetic parameters for a simple model have been estimated on basis of experimental observations performed under industrial conditions. The conclusions for the

  9. MASS TRANSFER KINETICS AND EFFECTIVE DIFFUSIVITIES DURING COCOA ROASTING

    Directory of Open Access Journals (Sweden)

    Y. M. BAGHDADI

    2017-01-01

    Full Text Available The current studies investigated the effects of temperature and moisture addition on the mass transfer kinetics of cocoa nibs during roasting. Experiments were carried out by roasting 500 gm of cocoa nibs inside an air ventilated oven at three temperature levels (120°C, 140°C and 160°C under medium air flowrate for one hour. Two types of samples were prepared namely the raw and soaked nib samples. The soaked nib samples were prepared by soaking the raw nibs in 200 ml of water at room temperature for 5 and 10 hours. Mathematical modelling was carried out to model the mass transfer process using semi-empirical models. Modelling showed that both Page and two-term models were able to give close fitting between the experimental and predicted values. Effective diffusivity values were estimated in the order of magnitude of 10-5 m2/s for the mass transfer process. Results obtained from these studies fill the current knowledge gap on the mass transfer kinetics of cocoa roasting.

  10. Kinetics and mass transfer phenomena in anaerobic granular sludge

    NARCIS (Netherlands)

    Gonzalez-Gil, G.; Seghezzo, L.; Lettinga, G.; Kleerebezem, R.

    2001-01-01

    The kinetic properties of acetate-degrading methanogenic granular sludge of different mean diameters were assessed at different up-flow velocities (Vup). Using this approach, the influence of internal and external mass transfer could be estimated. First, the apparent Monod constant (KS) for each

  11. Predicting the Liquid Phase Mass Transfer Resistance of Structured Packings

    NARCIS (Netherlands)

    Olujic, Z.; Seibert, A.F.

    2014-01-01

    Published correlations for estimating the liquid phase mass transfer coefficients of structured packings are compared using experimental evidence on the efficiency of Montz-Pak B1–250MN and B1–500MN structured packings as measured in total reflux distillation tests using the

  12. Simulation of heat and mass transfer in spray drying

    NARCIS (Netherlands)

    Lijn, van der J.

    1976-01-01

    A survey is given of heat and mass transfer around droplets in spray dryers and the diffusional transport inside them. A calculational model is developed which includes variable diffusion coefficients in the drying liquid and swelling or shrinking of droplets. Calculations for droplets

  13. Experimental and modeling studies of mass transfer in ...

    African Journals Online (AJOL)

    Gaining a better understanding of mass transfer problems in encapsulated cell systems and in ... the gas phase, Ci,m,i is the oxygen concentration on the inside of the membrane,. Q is the oxygen consumption rate of cells inside a microcapsule (mgO2/Lhr), QO2 is the ... air-lift bioreactor was investigated by studying.

  14. Heat and mass transfer in turbulent multiphase channel flow

    NARCIS (Netherlands)

    Bukhvostova, A.

    2015-01-01

    Direct numerical simulation is used to assess the importance of compressibility in turbulent channel flow of a mixture of air and water vapor with dispersed water droplets. The dispersed phase is allowed to undergo phase transition, which leads to heat and mass transfer between the phases. We

  15. Mass transfer analysis for terephthalic acid biodegradation by ...

    African Journals Online (AJOL)

    Biodegradation of terephthalic acid (TA) by polyvinyl alcohol (PVA)-alginate immobilized Pseudomonas sp. was carried out in a packed-bed reactor. The effect of inlet TA concentration on biodegradation was investigated at 30°C, pH 7 and flow rate of 20 ml/min. The effects of flow rate on mass transfer and biodegradation ...

  16. Gas-liquid mass transfer coefficient in stirred tank reactors

    NARCIS (Netherlands)

    Yawalkar, Archis A.; Heesink, Albertus B.M.; Versteeg, Geert; Pangarkar, Vishwas G.

    2003-01-01

    Volumetric gas—liquid mass transfer coefficient (kLa) data available in the literature for larger tanks (T = 0.39 m to 2.7 m) have been analyzed on the basis of relative dispersion parameter, N/Ncd. It was observed that at a given superficial gas velocity (VG), kLa values were approximately the same

  17. LUT observations of the mass-transferring binary AI Dra

    Science.gov (United States)

    Liao, Wenping; Qian, Shengbang; Li, Linjia; Zhou, Xiao; Zhao, Ergang; Liu, Nianping

    2016-06-01

    Complete UV band light curve of the eclipsing binary AI Dra was observed with the Lunar-based Ultraviolet Telescope (LUT) in October 2014. It is very useful to adopt this continuous and uninterrupted light curve to determine physical and orbital parameters of the binary system. Photometric solutions of the spot model are obtained by using the W-D (Wilson and Devinney) method. It is confirmed that AI Dra is a semi-detached binary with secondary component filling its critical Roche lobe, which indicates that a mass transfer from the secondary component to the primary one should happen. Orbital period analysis based on all available eclipse times suggests a secular period increase and two cyclic variations. The secular period increase was interpreted by mass transfer from the secondary component to the primary one at a rate of 4.12 ×10^{-8}M_{⊙}/yr, which is in agreement with the photometric solutions. Two cyclic oscillations were due to light travel-time effect (LTTE) via the presence of two cool stellar companions in a near 2:1 mean-motion resonance. Both photometric solutions and orbital period analysis confirm that AI Dra is a mass-transferring binary, the massive primary is filling 69 % of its critical Roche lobe. After the primary evolves to fill the critical Roche lobe, the mass transfer will be reversed and the binary will evolve into a contact configuration.

  18. Modelling of heat and mass transfer processes in neonatology

    Energy Technology Data Exchange (ETDEWEB)

    Ginalski, Maciej K [FLUENT Europe, Sheffield Business Park, Europa Link, Sheffield S9 1XU (United Kingdom); Nowak, Andrzej J [Institute of Thermal Technology, Silesian University of Technology, Konarskiego 22, 44-100 Gliwice (Poland); Wrobel, Luiz C [School of Engineering and Design, Brunel University, Uxbridge UB8 3PH (United Kingdom)], E-mail: maciej.ginalski@ansys.com, E-mail: Andrzej.J.Nowak@polsl.pl, E-mail: luiz.wrobel@brunel.ac.uk

    2008-09-01

    This paper reviews some of our recent applications of computational fluid dynamics (CFD) to model heat and mass transfer problems in neonatology and investigates the major heat and mass transfer mechanisms taking place in medical devices such as incubators and oxygen hoods. This includes novel mathematical developments giving rise to a supplementary model, entitled infant heat balance module, which has been fully integrated with the CFD solver and its graphical interface. The numerical simulations are validated through comparison tests with experimental results from the medical literature. It is shown that CFD simulations are very flexible tools that can take into account all modes of heat transfer in assisting neonatal care and the improved design of medical devices.

  19. Modelling of heat and mass transfer processes in neonatology

    International Nuclear Information System (INIS)

    Ginalski, Maciej K; Nowak, Andrzej J; Wrobel, Luiz C

    2008-01-01

    This paper reviews some of our recent applications of computational fluid dynamics (CFD) to model heat and mass transfer problems in neonatology and investigates the major heat and mass transfer mechanisms taking place in medical devices such as incubators and oxygen hoods. This includes novel mathematical developments giving rise to a supplementary model, entitled infant heat balance module, which has been fully integrated with the CFD solver and its graphical interface. The numerical simulations are validated through comparison tests with experimental results from the medical literature. It is shown that CFD simulations are very flexible tools that can take into account all modes of heat transfer in assisting neonatal care and the improved design of medical devices

  20. Heat and Mass Transfer Model in Freeze-Dried Medium

    Science.gov (United States)

    Alfat, Sayahdin; Purqon, Acep

    2017-07-01

    There are big problems in agriculture sector every year. One of the major problems is abundance of agricultural product during the peak of harvest season that is not matched by an increase in demand of agricultural product by consumers, this causes a wasted agricultural products. Alternative way was food preservation by freeze dried method. This method was already using heat transfer through conduction and convection to reduce water quality in the food. The main objective of this research was to design a model heat and mass transfer in freeze-dried medium. We had two steps in this research, the first step was design of medium as the heat injection site and the second was simulate heat and mass transfer of the product. During simulation process, we use physical property of some agriculture product. The result will show how temperature and moisture distribution every second. The method of research use finite element method (FEM) and will be illustrated in three dimensional.

  1. Overview of data acquisition and central control system of steady state superconducting Tokamak (SST-1)

    Energy Technology Data Exchange (ETDEWEB)

    Pradhan, S., E-mail: pradhan@ipr.res.in; Mahajan, K.; Gulati, H.K.; Sharma, M.; Kumar, A.; Patel, K.; Masand, H.; Mansuri, I.; Dhongde, J.; Bhandarkar, M.; Chudasama, H.

    2016-11-15

    Highlights: • The paper gives overview on SST-1 data acquisition and central control system and future upgrade plans. • The lossless PXI based data acquisition of SST-1 is capable of acquiring around 130 channels with sampling frequency ranging from 10 KHz to 1 MHz sampling frequency. • Design, architecture and technologies used for central control system (CCS) of SST-1. • Functions performed by CCS. - Abstract: Steady State Superconducting Tokamak (SST-1) has been commissioned successfully and has been carrying out limiter assisted ohmic plasma experiments since the beginning of 2014 achieving a maximum plasma current of 75 kA at a central field of 1.5 T and the plasma duration ∼500 ms. In near future, SST-1 looks forward to carrying out elongated plasma experiments and stretching plasma pulses beyond 1 s. The data acquisition and central control system (CCS) for SST-1 are distributed, modular, hierarchical and scalable in nature The CCS has been indigenously designed, developed, implemented, tested and validated for the operation of SST-1. The CCS has been built using well proven technologies like Redhat Linux, vxWorks RTOS for deterministic control, FPGA based hardware implementation, Ethernet, fiber optics backbone for network, DSP for real-time computation & Reflective memory for high-speed data transfer etc. CCS in SST-1 controls & monitors various heterogeneous SST-1 subsystems dispersed in the same campus. The CCS consists of machine control system, basic plasma control system, GPS time synchronization system, storage area network (SAN) for centralize data storage, SST-1 networking system, real-time networks, SST-1 control room infrastructure and many other supportive systems. Machine Control System (MCS) is a multithreaded event driven system running on Linux based servers, where each thread of the software communicates to a unique subsystem for monitoring and control from SST-1 central control room through network programming. The CCS hardware

  2. Overview of data acquisition and central control system of steady state superconducting Tokamak (SST-1)

    International Nuclear Information System (INIS)

    Pradhan, S.; Mahajan, K.; Gulati, H.K.; Sharma, M.; Kumar, A.; Patel, K.; Masand, H.; Mansuri, I.; Dhongde, J.; Bhandarkar, M.; Chudasama, H.

    2016-01-01

    Highlights: • The paper gives overview on SST-1 data acquisition and central control system and future upgrade plans. • The lossless PXI based data acquisition of SST-1 is capable of acquiring around 130 channels with sampling frequency ranging from 10 KHz to 1 MHz sampling frequency. • Design, architecture and technologies used for central control system (CCS) of SST-1. • Functions performed by CCS. - Abstract: Steady State Superconducting Tokamak (SST-1) has been commissioned successfully and has been carrying out limiter assisted ohmic plasma experiments since the beginning of 2014 achieving a maximum plasma current of 75 kA at a central field of 1.5 T and the plasma duration ∼500 ms. In near future, SST-1 looks forward to carrying out elongated plasma experiments and stretching plasma pulses beyond 1 s. The data acquisition and central control system (CCS) for SST-1 are distributed, modular, hierarchical and scalable in nature The CCS has been indigenously designed, developed, implemented, tested and validated for the operation of SST-1. The CCS has been built using well proven technologies like Redhat Linux, vxWorks RTOS for deterministic control, FPGA based hardware implementation, Ethernet, fiber optics backbone for network, DSP for real-time computation & Reflective memory for high-speed data transfer etc. CCS in SST-1 controls & monitors various heterogeneous SST-1 subsystems dispersed in the same campus. The CCS consists of machine control system, basic plasma control system, GPS time synchronization system, storage area network (SAN) for centralize data storage, SST-1 networking system, real-time networks, SST-1 control room infrastructure and many other supportive systems. Machine Control System (MCS) is a multithreaded event driven system running on Linux based servers, where each thread of the software communicates to a unique subsystem for monitoring and control from SST-1 central control room through network programming. The CCS hardware

  3. Bibliography on augmentation of convective heat and mass transfer

    Energy Technology Data Exchange (ETDEWEB)

    Bergles, A.E.; Webb, R.L.; Junkhan, G.H.; Jensen, M.K.

    1979-05-01

    Heat transfer augmentation has developed into a major specialty area in heat transfer research and development. A bibliography of world literature on augmentation is presented. The literature is classified into passive augmentation techniques, which require no external power, and active techniques, which do require external power. The fourteen techniques are grouped in terms of their application to the various modes of heat transfer. Mass transfer is included for completeness. Key words are included with each citation for technique/mode identification. The total number of publications cited is 1,967, including 75 surveys of various techniques and 42 papers on performance evaluation of passive techniques. Patents are not included as they will be the subject of a future topical report.

  4. Bibliography on augmentation of convective heat and mass transfer

    International Nuclear Information System (INIS)

    Bergles, A.E.; Webb, R.L.; Junkhan, G.H.; Jensen, M.K.

    1979-05-01

    Heat transfer augmentation has developed into a major specialty area in heat transfer research and development. A bibliography of world literature on augmentation is presented. The literature is classified into passive augmentation techniques, which require no external power, and active techniques, which do require external power. The fourteen techniques are grouped in terms of their application to the various modes of heat transfer. Mass transfer is included for completeness. Key words are included with each citation for technique/mode identification. The total number of publications cited is 1,967, including 75 surveys of various techniques and 42 papers on performance evaluation of passive techniques. Patents are not included as they will be the subject of a future topical report

  5. Fem Formulation for Heat and Mass Transfer in Porous Medium

    Science.gov (United States)

    Azeem; Soudagar, Manzoor Elahi M.; Salman Ahmed, N. J.; Anjum Badruddin, Irfan

    2017-08-01

    Heat and mass transfer in porous medium can be modelled using three partial differential equations namely, momentum equation, energy equation and mass diffusion. These three equations are coupled to each other by some common terms that turn the whole phenomenon into a complex problem with inter-dependable variables. The current article describes the finite element formulation of heat and mass transfer in porous medium with respect to Cartesian coordinates. The problem under study is formulated into algebraic form of equations by using Galerkin's method with the help of two-node linear triangular element having three nodes. The domain is meshed with smaller sized elements near the wall region and bigger size away from walls.

  6. Mass and charge transfer within a floating water bridge

    Science.gov (United States)

    Fuchs, Elmar C.; Agostinho, Luewton L. F.; Eisenhut, Mathias; Woisetschläger, Jakob

    2010-11-01

    When high voltage is applied to pure water filled into two beakers close to each other, a connection forms spontaneously, giving the impression of a floating water bridge 1-8. This phenomenon is of special interest, since it comprises a number of phenomena currently tackled in modern water science. In this work, the charge and mass transfer through the water bridge are investigated with schlieren visualization and laser interferometry. It can be shown that the addition of a pH dye increases the H+ and OH- production with subsequent electrolysis, whereas schlieren and interferometric methods reveal another mechanism where charge and mass transfer appear to be coupled. Whereas this mechanism seems to be responsible for the electrolysis-less charge and mass transfer in the water bridge, it is increasingly superseded by the electrochemical mechanism with rising conductivity. Thus it can be shown that a pH dye does only indirectly visualize the charge transfer in the water bridge since it is dragged along with the water flow like any other dye, and additionally promotes conventional electrochemical conduction mechanisms, thereby enhancing electrolysis and reducing the masscoupled charge transport and thus destabilizing the bridge.

  7. Response of tungsten surfaces to helium and hydrogen plasma exposure under ITER relevant steady state and repetitive transient conditions

    NARCIS (Netherlands)

    Buzi, L.; De Temmerman, G.; Huisman, A. E.; Bardin, S.; Morgan, T. W.; Rasinski, M.; Pitts, R. A.; Van Oost, G.

    2017-01-01

    The effect of helium (He) plasma exposure, and associated surface modifications, on the thermal shock resistance of tungsten (W) under ITER relevant steady state and transient heat and particle loads was studied. W samples were exposed to steady state and pulsed He plasmas at surface base

  8. Study of molecular iodine-epoxy paint mass transfer

    Energy Technology Data Exchange (ETDEWEB)

    Belval-Haltier, E. [Inst. de Protection et Surete Nucleaire, IPSN, CEN Cadarache, St. Paul-lez-Durance (France)

    1996-12-01

    The mass transfer phenomena may have a significant influence on the quantity of I{sub 2} which could be released following a severe accident of a nuclear power plant and specially the mass transfer of iodine onto containment surfaces. So, the objective of the present work was to evaluate which phase limited the adsorption process of iodine onto gaseous epoxy paint under a range of conditions which may be relevant to a severe reactor accident. In this aim, a series of experiments was conducted in which the sorption kinetics of molecular iodine, labelled with {sup 131}I, was measured by monitoring continuously the accumulation of this species on the epoxy surface. For each test condition, the initial deposition velocity was determined and the corresponding gas phase mass transfer, kg, was estimated by using the heat transfer analogy for a laminar flow passing over a flat plate. Then, the surface reaction rate, Kr, was deduced from these two values. Experiments performed indicated that iodine adsorption onto epoxy paint is highly dependent on temperature, relative humidity of the carrier gas and moisture content of the painted coupon. In dry air flow conditions, the adsorption of iodine onto paint was found to increase with temperature and to be limited by the surface reaction rate, Kr. The I{sub 2} adsorption rate was found to increase with the humidity of carrier gas and in some studied conditions, the initial deposition velocity appeared to be controlled by gas phase mass transfer rather than surface interaction. The same phenomenon has been observed with an increase of the initial water content of the painted coupon. (author) 6 figs., 1 tab., 8 refs.

  9. Method development for detecting divertor failures during steady state operation of Wendelstein 7X

    Energy Technology Data Exchange (ETDEWEB)

    Rodatos, Alexander; Jakubowski, Marcin; Sunn Pedersen, Thomas [Max Planck Institute for Plasma Physics, Wendelsteinstr. 1, Greifswald (Germany); Greuner, Henri [Max Planck Institute for Plasma Physics, Boltzmannstr. 2, Garching (Germany)

    2015-05-01

    Wendelstein 7-X (W7-X) is stellarator fusion experiment, which will start operation in 2015. One of its goals is the demonstration of the stellarator concepts steady state capability while operating with fusion relevant plasma parameters. For particle and heat exhaust from the plasma a set of 10 island divertor units is installed in the machine. During the steady state operation they are exposed to a heat flux of up to 10MW/m{sup 2} for up to 30 min. Transient, even higher heat fluxes are possible. To guarantee the save operation of W7-X a continues surveillance of the divertor is mandatory, which is realized by a set of 10 infrared cameras observing the divertor surface. These data needs to be evaluated during the experiment identifying defects, surface layers and actual hot spots caused by overheating.

  10. Stability of periodic steady-state solutions to a non-isentropic Euler-Poisson system

    Science.gov (United States)

    Liu, Cunming; Peng, Yue-Jun

    2017-06-01

    We study the stability of periodic smooth solutions near non-constant steady-states for a non-isentropic Euler-Poisson system without temperature damping term. The system arises in the theory of semiconductors for which the doping profile is a given smooth function. In this stability problem, there are no special restrictions on the size of the doping profile, but only on the size of the perturbation. We prove that small perturbations of periodic steady-states are exponentially stable for large time. For this purpose, we introduce new variables and choose a non-diagonal symmetrizer of the full Euler equations to recover dissipation estimates. This also allows to make the proof of the stability result very simple and concise.

  11. Comparing Interval Management Control Laws for Steady-State Errors and String Stability

    Science.gov (United States)

    Weitz, Lesley A.; Swieringa, Kurt A.

    2018-01-01

    Interval Management (IM) is a future airborne spacing concept that leverages avionics to provide speed guidance to an aircraft to achieve and maintain a specified spacing interval from another aircraft. The design of a speed control law to achieve the spacing goal is a key aspect in the research and development of the IM concept. In this paper, two control laws that are used in much of the contemporary IM research are analyzed and compared to characterize steady-state errors and string stability. Numerical results are used to illustrate how the choice of control laws gains impacts the size of steady-state errors and string performance and the potential trade-offs between those performance characteristics.

  12. Performance enhancement of steady-state Markov analysis for cognitive radio networks via channel reservation

    Directory of Open Access Journals (Sweden)

    Nehal M. El Azaly

    2017-12-01

    Full Text Available Cognitive radio wireless networks CRNs have been considered as an efficient communication paradigm to the utilization of scarce spectrum. The main purpose of channel reservation of dynamic spectrum access (DSA is to access these idle channels intelligently which are specialized for primary users (PUS to be used by unlicensed users temporarily, which are called secondary users (SUS without causing critical interference to the licensed user’s activity. In this paper, continuous-time Markov chain paradigm is improved via channel reservation to show the best usage of the radio spectrum bands, and the transition matrix are deduced for the proposed model. Moreover, the probability state vector is proved by performing steady state analysis. The deduced expressions of the suggested model are illustrated in the numerical results section. Keywords: Cognitive radio networks, Dynamic spectrum access, Channel reservation, Continuous-time Markov chain, Steady-state analysis

  13. Steady-State Somatosensory Evoked Potential for Brain-Computer Interface–Present and Future

    Directory of Open Access Journals (Sweden)

    Sangtae eAhn

    2016-01-01

    Full Text Available Brain-computer interface (BCI performance has achieved continued improvement over recent decades, and sensorimotor rhythm-based BCIs that use motor function have been popular subjects of investigation. However, it remains problematic to introduce them to the public market because of their low reliability. As an alternative resolution to this issue, visual-based BCIs that use P300 or steady-state visually evoked potentials seem promising; however, the inherent visual fatigue that occurs with these BCIs may be unavoidable. For these reasons, steady-state somatosensory evoked potential (SSSEP BCIs, which are based on tactile selective attention, have gained increasing attention recently. These may reduce the fatigue induced by visual attention and overcome the low reliability of motor activity. In this literature survey, recent findings on SSSEP and its methodological uses in BCI are reviewed. Further, existing limitations of SSSEP BCI and potential future directions for the technique are discussed.

  14. Basis adaptation and domain decomposition for steady-state partial differential equations with random coefficients

    Energy Technology Data Exchange (ETDEWEB)

    Tipireddy, R.; Stinis, P.; Tartakovsky, A. M.

    2017-12-01

    We present a novel approach for solving steady-state stochastic partial differential equations (PDEs) with high-dimensional random parameter space. The proposed approach combines spatial domain decomposition with basis adaptation for each subdomain. The basis adaptation is used to address the curse of dimensionality by constructing an accurate low-dimensional representation of the stochastic PDE solution (probability density function and/or its leading statistical moments) in each subdomain. Restricting the basis adaptation to a specific subdomain affords finding a locally accurate solution. Then, the solutions from all of the subdomains are stitched together to provide a global solution. We support our construction with numerical experiments for a steady-state diffusion equation with a random spatially dependent coefficient. Our results show that highly accurate global solutions can be obtained with significantly reduced computational costs.

  15. Composing Problem Solvers for Simulation Experimentation: A Case Study on Steady State Estimation

    Science.gov (United States)

    Leye, Stefan; Ewald, Roland; Uhrmacher, Adelinde M.

    2014-01-01

    Simulation experiments involve various sub-tasks, e.g., parameter optimization, simulation execution, or output data analysis. Many algorithms can be applied to such tasks, but their performance depends on the given problem. Steady state estimation in systems biology is a typical example for this: several estimators have been proposed, each with its own (dis-)advantages. Experimenters, therefore, must choose from the available options, even though they may not be aware of the consequences. To support those users, we propose a general scheme to aggregate such algorithms to so-called synthetic problem solvers, which exploit algorithm differences to improve overall performance. Our approach subsumes various aggregation mechanisms, supports automatic configuration from training data (e.g., via ensemble learning or portfolio selection), and extends the plugin system of the open source modeling and simulation framework James II. We show the benefits of our approach by applying it to steady state estimation for cell-biological models. PMID:24705453

  16. Steady-state pulses and superradiance in short-wavelength, swept-gain amplifiers

    International Nuclear Information System (INIS)

    Bonifacio, R.; Hopf, F.A.; Meystre, P.; Scully, M.O.

    1975-01-01

    The steady-state behavior of amplifiers in which the excitation is swept at the speed of light is discussed in the semiclassical approximation. In the present work the case where the decay time of the population is comparable to that of the polarization is examined. Pulse propagation is shown to obey a generalized sine-Gordon equation which contains the effects of atomic relaxations. The analytical expression of the steady-state pulses (SSP) gives two threshold conditions. In the region of limited gain the SSP is a broad pulse with small area which can be obtained by small signal theory. In the second region of high gain the SSP is the superradiant π pulse. Its pulse power is not limited as in usual superradiant theory because, as is shown, for a swept excitation the cooperation-length limit does not exist

  17. Basis adaptation and domain decomposition for steady-state partial differential equations with random coefficients

    Science.gov (United States)

    Tipireddy, R.; Stinis, P.; Tartakovsky, A. M.

    2017-12-01

    We present a novel approach for solving steady-state stochastic partial differential equations in high-dimensional random parameter space. The proposed approach combines spatial domain decomposition with basis adaptation for each subdomain. The basis adaptation is used to address the curse of dimensionality by constructing an accurate low-dimensional representation of the stochastic PDE solution (probability density function and/or its leading statistical moments) in each subdomain. Restricting the basis adaptation to a specific subdomain affords finding a locally accurate solution. Then, the solutions from all of the subdomains are stitched together to provide a global solution. We support our construction with numerical experiments for a steady-state diffusion equation with a random spatially dependent coefficient. Our results show that accurate global solutions can be obtained with significantly reduced computational costs.

  18. PEBBLE: a two-dimensional steady-state pebble bed reactor thermal hydraulics code

    Energy Technology Data Exchange (ETDEWEB)

    Vondy, D.R.

    1981-09-01

    This report documents the local implementation of the PEBBLE code to treat the two-dimensional steady-state pebble bed reactor thermal hydraulics problem. This code is implemented as a module of a computation system used for reactor core history calculations. Given power density data, the geometric description in (RZ), and basic heat removal conditions and thermal properties, the coolant properties, flow conditions, and temperature distributions in the pebble fuel elements are predicted. The calculation is oriented to the continuous fueling, steady state condition with consideration of the effect of the high energy neutron flux exposure and temperature history on the thermal conductivity. The coolant flow conditions are calculated for the same geometry as used in the neutronics calculation, power density and fluence data being used directly, and temperature results are made available for subsequent use.

  19. Steady State Thermo-Hydrodynamic Analysis of Two-Axial groove and Multilobe Hydrodynamic Bearings

    Directory of Open Access Journals (Sweden)

    C. Bhagat

    2014-12-01

    Full Text Available Steady state thermo-hydrodynamic analysis of two axial groove and multi lobe oil journal bearings is performed in this paper. To study the steady state thermo-hydrodynamic characteristics Reynolds equation is solved simultaneously along with the energy equation and heat conduction equation in bush and shaft. The effect of groove geometry, cavitation in the fluid film, the recirculation of lubricant, shaft speed has also been taken into account. Film temperature in case of three-lobe bearing is found to be high as compared to other studied bearing configurations. The data obtained from this analysis can be used conveniently in the design of such bearings, which are presented in dimensionless form.

  20. Rheological behavior of semi-solid 7075 aluminum alloy at steady state

    Directory of Open Access Journals (Sweden)

    Li Yageng

    2014-03-01

    Full Text Available The further application of semi-solid processing lies in the in-depth fundamental study like rheological behavior. In this research, the apparent viscosity of the semi-solid slurry of 7075 alloy was measured using a Couette type viscometer. The effects of solid fraction and shearing rate on the apparent viscosity of this alloy were investigated under different processing conditions. It can be seen that the apparent viscosity increases with an increase in the solid fraction from 10% to 50% (temperature 620 篊 to 630 篊 at steady state. When the solid fraction was fixed, the apparent viscosity can be decreased by altering the shearing rate from 61.235 s-1 to 489.88 s-1 at steady state. An empirical equation that shows the effects of solid fraction and shearing rate on the apparent viscosity is fitted. The microstructure of quenched samples was examined to understand the alloy抯 rheological behavior.