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Sample records for standard artificial diet

  1. Characterization of the Mamestra configurata (Lepidoptera: Noctuidae) larval midgut protease complement and adaptation to feeding on artificial diet, Brassica species, and protease inhibitor.

    Science.gov (United States)

    Erlandson, Martin A; Hegedus, Dwayne D; Baldwin, Douglas; Noakes, Amy; Toprak, Umut

    2010-10-01

    The midgut protease profiles from 5th instar Mamestra configurata larvae fed various diets (standard artificial diet, low protein diet, low protein diet with soybean trypsin inhibitor [SBTI], or Brassica napus) were characterized by one-dimensional enzymography in gelatin gels. The gut protease profile of larvae fed B. napus possessed protease activities of molecular masses of approximately 33 and 55 kDa, which were not present in the guts of larvae fed artificial diet. Similarly, larvae fed artificial diet had protease activities of molecular masses of approximately 21, 30, and 100 kDa that were absent in larvae fed B. napus. Protease profiles changed within 12 to 24 h after switching larvae from artificial diet to plant diet and vice versa. The gut protease profiles from larvae fed various other brassicaceous species and lines having different secondary metabolite profiles did not differ despite significant differences in larval growth rates on the different host plants. Genes encoding putative digestive proteolytic enzymes, including four carboxypeptidases, five aminopeptidases, and 48 serine proteases, were identified in cDNA libraries from 4th instar M. configurata midgut tissue. Many of the protease-encoding genes were expressed at similar levels on all diets; however, three chymoptrypsin-like genes (McSP23, McSP27, and McSP37) were expressed at much higher levels on standard artificial diet and diet containing SBTI as was the trypsin-like gene McSP34. The expression of the trypsin-like gene McSP50 was highest on B. napus. The adaptation of M. configurata digestive biochemistry to different diets is discussed in the context of the flexibility of polyphagous insects to changing diet sources.

  2. Suitability of an artificial diet for rape aphid, Brevicoryne brassicae ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-09-15

    Sep 15, 2009 ... Brevicoryne brassicae, using life table parameters. A. Balvasi1* ... In this work, suitability of an artificial diet was studied through age-specific life tables. Development ... In large measure, the success of entomology over the past century is ..... balance on the improvement of an artificial diet for a biotype of.

  3. Optimization an optimal artificial diet for the predatory bug Orius sauteri (hemiptera: anthocoridae.

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    Xiao-Ling Tan

    Full Text Available BACKGROUND: The flower bug Orius sauteri is an important polyphagous predator that is widely used for the biological control of mites and aphids. However, the optimal conditions for mass rearing of this insect are still unclear, thus limiting its application. METHODOLOGY: In this study, we investigated the optimal ingredients of an artificial diet for raising O. sauteri using a microencapsulation technique. The ingredients included egg yolk (vitellus, whole-pupa homogenate of the Tussah silk moth (Antheraea paphia, honey, sucrose, rapeseed (Brassica napus pollen and sinkaline. We tested 25 combinations of the above ingredients using an orthogonal experimental design. Using statistical analysis, we confirmed the main effect factors amongst the components, and selected five optimal combinations based on different biological and physiological characters. PRINCIPAL FINDINGS: The results showed that, although different artificial diet formats significantly influenced the development and reproductive ability of O. sauteri, the complete development of O. sauteri to sexual maturity could only be achieved by optimizing the artificial diet according to specific biological characters. In general, pupae of A. paphia had more influence on O sauteri development than did artificial components. The results of a follow-up test of locomotory and respiratory capacity indicated that respiratory quotient, metabolic rate and average creeping speed were all influenced by different diets. Furthermore, the field evaluations of mating preference, predatory consumption and population dispersion also demonstrated the benefits that could be provided by optimal artificial diets. CONCLUSIONS: A microencapsulated artificial diet overcame many of the difficulties highlighted by previous studies on the mass rearing of O. sauteri. Optimization of the microencapsulated artificial diet directly increased the biological and physiological characters investigated. Successive

  4. Development of a dry artificial diet for Nezara viridula (L.) and Euschistus heros (Fabricius) (Heteroptera: Pentatomidae)

    International Nuclear Information System (INIS)

    Fortes, Priscila; Parra, Jose R.P.; Panizzi, Antonio R.

    2006-01-01

    Artificial diets prepared with wheat germ, soybean protein, dextrosol, potato starch, sucrose, cellulose, soybean or sunflower oil, and vitamin solution for rearing Nezara viridula (L.) and Euschistus heros (Fabricius) were tested under controlled temperature (25 ± 1 deg C), RH (60 ± 10%), and photophase (14h). Three diets were tested and compared with the natural diet privet [soybean and peanut seeds and privet Ligustrum lucidum Ait. fruit (Oleaceae)]. All three artificial diets allowed full development. The diet containing sunflower oil was the most suitable for N. viridula while E. heros developed better on a diet composed of soybean oil. Data indicated that the artificial diets were inferior to the natural diet. The artificial diets were more adequate for E. heros. (author)

  5. Development of a dry artificial diet for Nezara viridula (L.) and Euschistus heros (Fabricius) (Heteroptera: Pentatomidae)

    Energy Technology Data Exchange (ETDEWEB)

    Fortes, Priscila; Parra, Jose R.P. [Universidade de Sao Paulo (USP), Piracicaba, SP (Brazil). Escola Superior de Agricultura Luiz de Queiroz (ESALQ). Dept. Entomologia, Fitopatologia e Zoologia Agricola; Magro, Sandra R. [Faculdade Integrada de Campo Mourao, PR (Brazil); Panizzi, Antonio R. [EMBRAPA, Londrina, PR (Brazil). Centro Nacional de Pesquisa de Soja

    2006-09-15

    Artificial diets prepared with wheat germ, soybean protein, dextrosol, potato starch, sucrose, cellulose, soybean or sunflower oil, and vitamin solution for rearing Nezara viridula (L.) and Euschistus heros (Fabricius) were tested under controlled temperature (25 {+-} 1 deg C), RH (60 {+-} 10%), and photophase (14h). Three diets were tested and compared with the natural diet privet [soybean and peanut seeds and privet Ligustrum lucidum Ait. fruit (Oleaceae)]. All three artificial diets allowed full development. The diet containing sunflower oil was the most suitable for N. viridula while E. heros developed better on a diet composed of soybean oil. Data indicated that the artificial diets were inferior to the natural diet. The artificial diets were more adequate for E. heros. (author)

  6. Receptivity of winter flounder larvae to artificial diet from the yolk-sac stage to metamorphosis

    DEFF Research Database (Denmark)

    Butts, Ian; Ben Khemis, I.; Litvak, Matthew Kenneth

    2015-01-01

    In the period from 4 days post-hatching to metamorphosis, winter flounder that were naïve to artificial feed were exposed to an artificial diet and allowed to forage for 8 min. The presence or absence of artificial diet in the gut was used as an indicator of acceptance. The relationship between...

  7. Protein levels and colony development of Africanized and European honey bees fed natural and artificial diets.

    Science.gov (United States)

    Morais, M M; Turcatto, A P; Pereira, R A; Francoy, T M; Guidugli-Lazzarini, K R; Gonçalves, L S; de Almeida, J M V; Ellis, J D; De Jong, D

    2013-12-19

    Pollen substitute diets are a valuable resource for maintaining strong and health honey bee colonies. Specific diets may be useful in one region or country and inadequate or economically unviable in others. We compared two artificial protein diets that had been formulated from locally-available ingredients in Brazil with bee bread and a non-protein sucrose diet. Groups of 100 newly-emerged, adult workers of Africanized honey bees in Brazil and European honey bees in the USA were confined in small cages and fed on one of four diets for seven days. The artificial diets included a high protein diet made of soy milk powder and albumin, and a lower protein level diet consisting of soy milk powder, brewer's yeast and rice bran. The initial protein levels in newly emerged bees were approximately 18-21 µg/µL hemolymph. After feeding on the diets for seven days, the protein levels in the hemolymph were similar among the protein diet groups (~37-49 µg/µL after seven days), although Africanized bees acquired higher protein levels, increasing 145 and 100% on diets D1 and D2, respectively, versus 83 and 60% in the European bees. All the protein diets resulted in significantly higher levels of protein than sucrose solution alone. In the field, the two pollen substitute diets were tested during periods of low pollen availability in the field in two regions of Brazil. Food consumption, population development, colony weight, and honey production were evaluated to determine the impact of the diets on colony strength parameters. The colonies fed artificial diets had a significant improvement in all parameters, while control colonies dwindled during the dearth period. We conclude that these two artificial protein diets have good potential as pollen substitutes during dearth periods and that Africanized bees more efficiently utilize artificial protein diets than do European honey bees.

  8. Biology and fertility life table of Agrotis ipsilon on artificial diet

    International Nuclear Information System (INIS)

    Bento, Flavia de Moura Manoel; Fortes, Priscila; Zerio, Neide Graciano; Parra, Jose Roberto Postali

    2007-01-01

    The objective of this work was to develop an artificial diet to rear Agrotis ipsilon in laboratory using biological parameters and fertility life table. The artificial diet was prepared with bean, casein, soybean protein, yeast and wheat germ as protein sources. The biological aspects duration and viability of larval and pupal stages, pupal weight, sex ratio, life span of adults, preoviposition period, egg laying capacity and fertility life table were evaluated. Six larval instars were observed comprising larval duration of 28,4 days and 93% of viability mean pupal duration of 12,4 days and viability of 96%. The total viability of the life cycle was 72%. The pupae weight was 387 mg for males and 484 mg for females. The sex ratio was 0,46 and the preoviposition period lasted one day and egg laying was 1,806 eggs per female. The net reproductive rate per generation and increase finite rate were 616,9 and 1,14, respectively. Artificial diet is adequate for rearing A. ipsilon in laboratory. (author)

  9. Sensitivity of Ceratitis capitata eggs irradiated in artificial diet and in mango fruits

    International Nuclear Information System (INIS)

    Raga, A.; Yasuoka, S.T.; Amorim, E.O.; Sato, M.E.; Suplicy Filho, N.; Faria, J.T. de

    1996-01-01

    The objective of this study was to establish gamma radiation doses required to prevent emergence of Ceratitis capitata adults, from irradiated eggs in artificial diet and mango fruits. Six-, twelve-, twenty-four-, and forty-eight-hour-old eggs were used. Artificial infestation by C. capitata was carried out in mangoes of Haden, Tommy and Keith cultivars. An increase of radiation resistance of C. capitata eggs was observed as a function of the embryonic development and a Probit 9 of 24.67 Gy was estimated for 48-hour-old eggs in artificial diet. No significant influence of mango fruits was found on the efficacy of irradiation. (author)

  10. Development and reprotuction of Spodoptera eridania on natural hosts and artificial diet

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    A. Silva

    2018-04-01

    Full Text Available Abstract The development and reproductive potential of Spodoptera eridania (Stoll, 1782 (Lepidoptera, Noctuidae was compared on natural and artificial diets. Its biology was determined under laboratory conditions, providing an artificial diet, leaves of white clover and the peach cultivar 'Chimarrita' and fruits and leaves of the apple cultivar 'Gala'. Larvae of S. eridania could not complete their biological cycle when fed on apple fruits or peach leaves. The artificial diet provided the shortest development time, with a cycle of 28.5±0.14 days from egg to adult and 37.3% total viability. Apple leaves led to a longer development time from egg to adult (62.8±1.22 days and lower total viability (23% and white clover provided the highest total viability (54.3%. The results showed that S. eridania can use white clover and apple leaves to develop normally in apple orchards. The reduction of food sources such as white clover used by the larvae results in infestation and damage to fruits from “test bites”.

  11. Development and reprotuction of Spodoptera eridania on natural hosts and artificial diet.

    Science.gov (United States)

    Silva, A; Baronio, C A; Galzer, E C W; Garcia, M S; Botton, M

    2018-04-09

    The development and reproductive potential of Spodoptera eridania (Stoll, 1782) (Lepidoptera, Noctuidae) was compared on natural and artificial diets. Its biology was determined under laboratory conditions, providing an artificial diet, leaves of white clover and the peach cultivar 'Chimarrita' and fruits and leaves of the apple cultivar 'Gala'. Larvae of S. eridania could not complete their biological cycle when fed on apple fruits or peach leaves. The artificial diet provided the shortest development time, with a cycle of 28.5±0.14 days from egg to adult and 37.3% total viability. Apple leaves led to a longer development time from egg to adult (62.8±1.22 days) and lower total viability (23%) and white clover provided the highest total viability (54.3%). The results showed that S. eridania can use white clover and apple leaves to develop normally in apple orchards. The reduction of food sources such as white clover used by the larvae results in infestation and damage to fruits from "test bites".

  12. Artificial Diets for Mosquitoes

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    Kristina K. Gonzales

    2016-12-01

    Full Text Available Mosquito-borne diseases are responsible for more than a million human deaths every year. Modern mosquito control strategies such as sterile insect technique (SIT, release of insects carrying a dominant lethal (RIDL, population replacement strategies (PR, and Wolbachia-based strategies require the rearing of large numbers of mosquitoes in culture for continuous release over an extended period of time. Anautogenous mosquitoes require essential nutrients for egg production, which they obtain through the acquisition and digestion of a protein-rich blood meal. Therefore, mosquito mass production in laboratories and other facilities relies on vertebrate blood from live animal hosts. However, vertebrate blood is expensive to acquire and hard to store for longer times especially under field conditions. This review discusses older and recent studies that were aimed at the development of artificial diets for mosquitoes in order to replace vertebrate blood.

  13. Whitefly feeding behavior and retention of a foregut-borne crinivirus exposed to artificial diets with different pH values.

    Science.gov (United States)

    Zhou, Jaclyn S; Chen, Angel Y S; Drucker, Martin; Lopez, Nicole H; Carpenter, Alyssa; Ng, James C K

    2017-12-01

    Transmission of plant viruses by phytophagous hemipteran insects encompasses complex interactions underlying a continuum of processes involved in virus acquisition, retention and inoculation combined with vector feeding behavior. Here, we investigated the effects of dietary pH on whitefly (Bemisia tabaci) feeding behavior and release of Lettuce infectious yellows virus (LIYV) virions retained in the vector's foregut. Electrical penetration graph analysis revealed that variables associated with whitefly probing and ingestion did not differ significantly in pH (4, 7.4, and 9) adjusted artificial diets. To investigate virus retention and release, whiteflies allowed to acquire LIYV virions in a pH 7.4 artificial diet were fed pH 4, 7.4, or 9 virion-free artificial (clearing) diets. Immunofluorescent localization analyses indicated that virions remained bound to the foreguts of approximately 20%-24% of vectors after they fed on each of the 3 pH-adjusted clearing diets. When RNA preparations from the clearing diets were analyzed by reverse transcription (RT) nested-PCR and, in some cases, real-time qPCR, successful amplification of LIYV-specific sequence was infrequent but consistently repeatable for the pH 7.4 diet but never observed for the pH 4 and 9 diets, suggesting a weak pH-dependent effect for virion release. Viruliferous vectors that fed on each of the 3 pH-adjusted clearing diets transmitted LIYV to virus-free plants. These results suggest that changes in pH values alone in artificial diet do not result in observable changes in whitefly feeding behaviors, an observation that marks a first in the feeding of artificial diet by whitefly vectors; and that there is a potential causal and contingent relationship between the pH in artificial diet and the release/inoculation of foregut bound virions. © 2017 Institute of Zoology, Chinese Academy of Sciences.

  14. Rearing the southern green stink bug using an artificial dry diet and an artificial plant Criação do percevejo-verde usando dieta artificial seca e planta artificial

    Directory of Open Access Journals (Sweden)

    ANTÔNIO RICARDO PANIZZI

    2000-09-01

    Full Text Available Laboratory and greenhouse studies were conducted with an artificial dry diet to rear nymphs, and with an artificial plant as substrate for egg laying by the southern green stink bug, Nezara viridula (L.. The artificial diet was composed of: soybean protein (15 g; potato starch (7.5 g; dextrose (7.5 g; sucrose (2.5 g; cellulose (12.5 g; vitamin mixture (niacinamide 1 g, calcium pantothenate 1 g, thiamine 0.25 g, riboflavin 0.5 g, pyridoxine 0.25 g, folic acid 0.25 g, biotin 0.02 mL, vitamin B12 1 g - added to 1,000 mL of distilled water (5.0 mL; soybean oil (20 mL; wheat germ (17.9 g; and water (30 mL. Nymphs showed normal feeding behavior when fed on the artificial diet. Nymphal development time was longer than or similar to that of nymphs fed on soybean pods. Total nymphal mortality was low (ca. 30%, both for nymphs reared on the artificial diet, and for nymphs fed on soybean pods. At adult emergence, fresh body weights were significantly (PForam conduzidos estudos em laboratório e em casa de vegetação, com uma dieta artificial seca para a criação de ninfas e com um modelo de planta artificial como substrato para a colocação de ovos por adultos do percevejo-verde, Nezara viridula (L.. Os componentes da dieta artificial foram: proteína de soja (15 g; fécula de batata (7,5 g; dextrose (7,5 g; sacarose (2,5 g; celulose (12,5 g; mistura vitamínica (niacinamida 1 g, pantotenato de cálcio 1 g, tiamina 0,25 g, riboflavina 0,5 g, piridoxina 0,25 g, ácido fólico 0,25 g, biotina 0,02 mL, vitamina B12 1 g, adicionada em 1.000 mL de água destilada (5,0 mL; óleo de soja (20 mL; germe de trigo (17,9 g; e água (30 mL. As ninfas alimentaram-se normalmente da dieta, embora o tempo de desenvolvimento tenha sido em um caso, maior, e em outro, semelhante, ao das ninfas que se alimentaram de vagens da soja. A mortalidade total das ninfas foi baixa (ca. 30%, tanto na dieta como na vagem de soja. Na emergência, os adultos apresentaram peso fresco

  15. Freeze dried blood and development of an artificial diet for blood feeding arthropods

    International Nuclear Information System (INIS)

    DeLoach, J.R.; Spates, G.E.; Kapatsa, G.M.; Sheffield, C.L.; Kabayo, J.P.

    1990-01-01

    The goals of the research were to determine the biochemical differences between freeze dried bovine and porcine blood relative to their nutritional value to Glossina palpalis palpalis and Stomoxys calcitrans and to develop an artificial diet for mass rearing these flies. Freeze dried bovine and porcine blood were found to differ in their amino acid content; total dietary lipids did not significantly differ, but some notable exceptions were found in fatty acid content. Both sonication and addition of foetal bovine serum to freeze dried bovine blood improved its nutritional value for G. p. palpalis. A two component, semi-defined artificial diet was developed for G. p. palpalis and S. calcitrans. The College Station diet consisted of lipid contaminated bovine haemoglobin (BHb) and bovine serum albumin (BSA). To conduct dietary deletion tests, a process was developed for preparing large quantities of ultrapure lipid free bovine haemoglobin. S. calcitrans fed on lipid free BHb plus BSA had zero fecundity. Lipids were re-added to the protein diet in three forms: (1) lipid contaminated BHb, (2) pure erythrocyte ghosts, and (3) pure lipids. It was found that membrane lipid from the erythrocyte is required by S. calcitrans. A defined artificial diet consisting of lipid free BHb, BSA, sphingomyelin, phosphatidyl ethanolamine, phosphatidyl serine and cholesterol gave normal adult survival, as well as near normal fecundity and percentage egg hatch for S. calcitrans. Knowing the identity of the lipids, it is now possible to prepare dietary formulations to alleviate dependency on the blood proteins BHb and BSA. (author). 34 refs, 1 fig., 15 tabs

  16. Enhancement of the reproductive potential of Mallada boninensis Okamoto (Neuroptera: Chrysopidae, a predator of red spider mite infesting tea: An evaluation of artificial diets

    Directory of Open Access Journals (Sweden)

    Vasanthakumar Duraikkannu

    2012-01-01

    Full Text Available Green lacewing Mallada boninensis is an important predator of various soft-bodied arthropods, including red spider mites in tea. Efforts were made to develop mass rearing technology for this predator in a cost effective manner. Three combinations of artificial diets (Protinex (AD1, egg yolk (AD2 and royal jelly (AD3 based were evaluated in comparison with standard diet (Protinex + Honey. All the tested diets influenced the egg-laying capacity of M. boninensis. The egg yolk-based diet resulted in more egg production than the other two diets. Survival of all life stages of M. boninensis was also observed on each diet and no significant difference was noticed. Results revealed that the egg yolk-based diet is the best of the three diet combinations tested in view of high fecundity and survival rate of M. boninensis.

  17. Biology and fertility life table of Agrotis ipsilon on artificial diet; Biologia e tabela de vida de fertilidade de Agrotis ipsilon em dieta artificial

    Energy Technology Data Exchange (ETDEWEB)

    Bento, Flavia de Moura Manoel; Fortes, Priscila; Zerio, Neide Graciano; Parra, Jose Roberto Postali [Universidade de Sao Paulo (USP), Piracicaba, SP (Brazil). Escola Superior de Agricultura Luiz de Queiroz (ESALQ). Dept. Entomologia, Fitopatologia e Zoologia Agricola]. E-mail: flaviam@esalq.usp.br, pfortes@esalq.usp.br, ngzerio@esalq.usp.br, jrpparra@esalq.usp.br; Magro, Sandra Regina [Universidade Camilo Castelo Branco, Fernandopolis, SP (Brazil)]. E-mail: sandra.magro@gmail.com

    2007-10-15

    The objective of this work was to develop an artificial diet to rear Agrotis ipsilon in laboratory using biological parameters and fertility life table. The artificial diet was prepared with bean, casein, soybean protein, yeast and wheat germ as protein sources. The biological aspects duration and viability of larval and pupal stages, pupal weight, sex ratio, life span of adults, preoviposition period, egg laying capacity and fertility life table were evaluated. Six larval instars were observed comprising larval duration of 28,4 days and 93% of viability mean pupal duration of 12,4 days and viability of 96%. The total viability of the life cycle was 72%. The pupae weight was 387 mg for males and 484 mg for females. The sex ratio was 0,46 and the preoviposition period lasted one day and egg laying was 1,806 eggs per female. The net reproductive rate per generation and increase finite rate were 616,9 and 1,14, respectively. Artificial diet is adequate for rearing A. ipsilon in laboratory. (author)

  18. Some factors relating to the larval growth of the Colorado potato beetle, Leptinotarsa decemlineata Say (Coleoptera: Chrysomelidae), on artificial diets

    NARCIS (Netherlands)

    Wardojo, S.

    1969-01-01

    A brief account of the history of the development of artificial diets for phytophagous insects is given. Some conceptions with regard to terminology are discussed (chapter 3).

    Artificial diets for the larvae of the Colorado potato beetle, Leptinotarsa decemlineata Say, were developed

  19. Gain weight by "going diet?" Artificial sweeteners and the neurobiology of sugar cravings: Neuroscience 2010.

    Science.gov (United States)

    Yang, Qing

    2010-06-01

    America's obesity epidemic has gathered much media attention recently. A rise in the percent of the population who are obese coincides with an increase in the widespread use of non-caloric artificial sweeteners, such as aspartame (e.g., Diet Coke) and sucralose (e.g., Pepsi One), in food products (Figure 1). Both forward and reverse causalities have been proposed. While people often choose "diet" or "light" products to lose weight, research studies suggest that artificial sweeteners may contribute to weight gain. In this mini-review, inspired by a discussion with Dr. Dana Small at Yale's Neuroscience 2010 conference in April, I first examine the development of artificial sweeteners in a historic context. I then summarize the epidemiological and experimental evidence concerning their effects on weight. Finally, I attempt to explain those effects in light of the neurobiology of food reward.

  20. Feeding indices and enzymatic activities of carob moth Ectomyelois ceratoniae (Zeller (Lepidoptera: pyrallidae on two commercial pistachio cultivars and an artificial diet

    Directory of Open Access Journals (Sweden)

    Naeimeh Teimouri

    2015-01-01

    Full Text Available Feeding indices and enzymatic activities of Ectomyelois ceratoniae (Zeller were studied in a growth chamber under controlled conditions (29 ± 2 °C, relative humidity of 70 ± 5% and a photoperiod of 16:8 (L:D hours on two commercial Pistachio cultivars (Akbari and Kalequchi and an artificial diet. Feeding indices of E. ceratoniae larvae differed significantly on three hosts (P < 0.05. The relative consumption rate was calculated to be 5.36 ± 0.009, 11.10 ± 1.49 and 10.631 ± 0.599 (mg/mg/day on artificial diet, Akbari and Kalequchi cultivars, respectively. Carob moth larvae reared on Akbari cultivar showed the highest efficiency of conversion of digested food (ECD (5.64 ± 0.43. The highest amount of efficiency of conversion of ingested food (ECI was obtained on artificial diet but approximate digestibility (AD was the lowest on this diet. The highest enzymatic activities of alpha-amylase, general proteases and lipase were observed in the midgut of larvae reared on artificial diet. Total protein and lipid value were highest in larvae that were reared on artificial diet.

  1. Midgut Protease Activity During Larval Development of Anastrepha obliqua (Diptera: Tephritidae) Fed With Natural and Artificial Diet

    Science.gov (United States)

    Rivera-Ciprian, José Pedro; Aceituno-Medina, Marysol; Guillen, Karina

    2017-01-01

    Abstract In this study, we examined the activity of two serine proteases (chymotrypsin and trypsin) and two metalloproteases (carboxypeptidases A and B) during larval development in Anastrepha obliqua fed natural (mango fruit) and artificial (formulation used in mass-rearing) diets. Proteolytic activity of chymotrypsin, trypsin, carboxypeptidase A, and carboxypeptidase B was detected in the midgut of different instars of A. obliqua and was strongly affected by the pH and diet type. The protein content of the natural and artificial diets was similar. Enzymatic activity was higher in the midgut of the larvae fed the natural diet than in larvae fed the artificial diet. The activity of the endopeptidases (chymotrypsin and trypsin) was lower than those of the exopeptidases (carboxypeptidases A and B). The pH of the midgut varied from acidic to neutral. The results indicate that in the midgut of the larvae reared on both types of diet, the level of carboxypeptidase activity was approximately 100-fold greater than the level of chymotrypsin activity and 10,000-fold greater than the level of trypsin. In conclusion, carboxypeptidase A and B are the main proteases involved in the digestion of proteins in the larvae of A. obliqua. The natural diet showed a high bioaccessibility. A clear tendency to express high activities of chymotrypsin and trypsin was observed by the third instar. Our research contributes to the planning and development of novel bioaccessibility assays to understand the nutrition processing of A. obliqua larvae under mass-rearing conditions for sterile insect technique.

  2. Daily intakes of radionuclides in Japanese standard diets

    International Nuclear Information System (INIS)

    Terada, H.; Sugiyama, H.; Iijima, I.; Isomura, K.; Kobayashi, J.

    2005-01-01

    Daily intakes of radionuclides in Japanese standard diets were investigated. Food samples were collected from 9 cities of Japan using the market basket method according to the reports of National Nutrition Study in Japan (2000). These samples were categorized the following 14 groups; Group l: rice, rice products; Group 2: grain, seeds, potato; Group 3: sugar, confectionery; Group 4: oils and fats; Group 5: beans; Group 6: fruits; Group 7: green and yellow vegetables; Group 8: other vegetables; mushrooms, seaweed; Group 9: seasoning, drinks; Group 10: fish and shellfish; Group 11: meat, eggs; Group 12: milk, milk products; Group 13: other foods; and Group 14 was drinking water. Each group was homogenized separately after cooking the food materials. Determination of radioactivity was performed by gamma ray spectrometry. The only artificial radionuclide detected from gamma ray spectrometry was 137 CS, and its concentrations of each sample were almost less than 0.1 Bq/kg. Strontium-90 and 238 U concentrations of the total diet samples were analyzed with chemical separation. The concentrations of 90 Sr and 238 U were in the range of 0.013-0.031 Bq/kg, 0.0039-0.014 Bq/kg respectively, and a large difference was not found among the concentrations of each nuclide in 9 cities. We would like to estimate internal radiation dose to Japanese population from the dietary intakes of these radionuclides.

  3. Protein levels and colony development of Africanized and European honey bees fed natural and artificial diets

    OpenAIRE

    Morais, Michelle Manfrini [UNIFESP; Turcatto, Aline Patricia; Pereira, Rogerio Aparecido; Francoy, Tiago Mauricio; Guidugli-Lazzarini, Karina Rosa; Goncalves, Lionel Segui; Almeida, Joyce Mayra Volpini de; Ellis, J. D.; De Jong, David

    2013-01-01

    Pollen substitute diets are a valuable resource for maintaining strong and health honey bee colonies. Specific diets may be useful in one region or country and inadequate or economically unviable in others. We compared two artificial protein diets that had been formulated from locally-available ingredients in Brazil with bee bread and a non-protein sucrose diet. Groups of 100 newly-emerged, adult workers of Africanized honey bees in Brazil and European honey bees in the USA were confined in s...

  4. Survival and phenology of Agrilus planipennis (Coleoptera: Buprestidae) reared on a newly developed artificial diet free of host material

    Science.gov (United States)

    Melody A. Keena; Hannah Nadel; Juli. Gould

    2015-01-01

    The final phase in the development of an artificial diet that contains no ash host material and the phenology of the emerald ash borer, Agrilus planipennis Fairmaire (Coleoptera: Bupresidae) on that diet are documented. A diet containing powdered ash phloem exists, but host material introduces potential variability and contamination, and the cost and...

  5. Biology and fertility life table of Hypercompe indecisa on artificial diet

    International Nuclear Information System (INIS)

    Nava, Dori Edson; Diez-Rodriguez, Gabriela Ines; Melo, Mirtes; Afonso, Ana Paula Schneid

    2008-01-01

    The objective of this work was to study the biology of Hypercompe indecisa and construct a life table of fertility on an artificial diet, aiming at insect rearing in the laboratory. The following variables were determined: duration and survival of egg, larval and pupal phases; number of larval stages; sexual ratio; pupal weight; longevity; fecundity; and the period of pre-oviposition and oviposition. The embrionary, larval and pupal phases were 6, 25.4 and 64.3 days, with survival of 92.7, 92 and 71.9%, respectively. Six larval stages with variable durations were observed. Pupal weight was 1.04 g for females and 0.726 g for males. The biological cycle was 95.6 days, with 61.3% total survival. Females laid in average 1,531 eggs, during 8.3 days, with a pre-oviposition period of two days. The average longevity of males and females was 21.9 and 21.8 days, respectively, and the sexual ratio of males to females was 0.54. Increase of H. indecisa was 283 times through each generation, with the generation average duration of 98 days, and the fi nite ratio of increase of 1.0593. The used artificial diet was adequate for rearing H. indecisa, in the laboratory. (author)

  6. Comparison of several artificial diets with different protein sources for massal rearing of Ecdytolopha aurantiana (Lima) (Lepidoptera: Tortricidae)

    International Nuclear Information System (INIS)

    Garcia, Mauro S.; Parra, Jose R.P.

    1999-01-01

    The development of Ecdytolopha aurantiana (Lima) was compared among four artificial diets with different protein sources based on biological characteristics and fertility life table in order to have the insect available throughout the year for research in different areas. All diets with variable protein sources (D1= bean, yeast, wheat germ, soybean protein and casein; D2= corn flour, wheat germ, and yeast; D3= soybean protein, and wheat germ; D4= bean, yeast and wheat germ) allowed the insect to developed at 27 +- 2 deg C; RH 65 +- 10% and 14 h photophase. In all diets the insect presented four instars with several other similar biological characteristics. Since diet D2 (corn flour, wheat germ and yeast) provided the lowest development time, the highest viability, a high value of finite ratio of increase (ll), besides being of low cost and easy preparation, it can be considered as the most adequate for laboratory rearing of E. aurantiana. Balanced nutrients showed more important than the nutritional value of the components of the diet for this insect which is, for the first time, fed on artificial diet. (author)

  7. Nutrigenomics in Arma chinensis: transcriptome analysis of Arma chinensis fed on artificial diet and Chinese oak silk moth Antheraea pernyi pupae.

    Directory of Open Access Journals (Sweden)

    Deyu Zou

    Full Text Available BACKGROUND: The insect predator, Arma chinensis, is capable of effectively controlling many pests, such as Colorado potato beetle, cotton bollworm, and mirid bugs. Our previous study demonstrated several life history parameters were diminished for A. chinensis reared on an artificial diet compared to a natural food source like the Chinese oak silk moth pupae. The molecular mechanisms underlying the nutritive impact of the artificial diet on A. chinensis health are unclear. So we utilized transcriptome information to better understand the impact of the artificial diet on A. chinensis at the molecular level. METHODOLOGY/PRINCIPAL FINDINGS: Illumina HiSeq2000 was used to sequence 4.79 and 4.70 Gb of the transcriptome from pupae-fed and artificial diet-fed A. chinensis libraries, respectively, and a de novo transcriptome assembly was performed (Trinity short read assembler. This resulted in 112,029 and 98,724 contigs, clustered into 54,083 and 54,169 unigenes for pupae-fed and diet-fed A. chinensis, respectively. Unigenes from each sample's assembly underwent sequence splicing and redundancy removal to acquire non-redundant unigenes. We obtained 55,189 unigenes of A. chinensis, including 12,046 distinct clusters and 43,143 distinct singletons. Unigene sequences were aligned by BLASTx to nr, Swiss-Prot, KEGG and COG (E-value <10(-5, and further aligned by BLASTn to nt (E-value <10(-5, retrieving proteins of highest sequence similarity with the given unigenes along with their protein functional annotations. Totally, 22,964, 7,898, 18,069, 15,416, 8,066 and 5,341 unigenes were annotated in nr, nt, Swiss-Prot, KEGG, COG and GO, respectively. We compared gene expression variations and found thousands of genes were differentially expressed between pupae-fed and diet-fed A. chinensis. CONCLUSIONS/SIGNIFICANCE: Our study provides abundant genomic data and offers comprehensive sequence information for studying A. chinensis. Additionally, the physiological

  8. Sensitivity of Ceratitis capitata eggs irradiated in artificial diet and in mango fruits; Sensibilidade de ovos de Ceratitis capitata (WIED.,1824) irradiados em dieta artificial e em frutos de manga (Mangifera indica L.)

    Energy Technology Data Exchange (ETDEWEB)

    Raga, A.; Yasuoka, S.T.; Amorim, E.O.; Sato, M.E.; Suplicy Filho, N. [Instituto Biologico, Campinas, SP (Brazil); Faria, J.T. de [Delegacia Federal de Agricultura, Sao Paulo, SP (Brazil)

    1996-01-01

    The objective of this study was to establish gamma radiation doses required to prevent emergence of Ceratitis capitata adults, from irradiated eggs in artificial diet and mango fruits. Six-, twelve-, twenty-four-, and forty-eight-hour-old eggs were used. Artificial infestation by C. capitata was carried out in mangoes of Haden, Tommy and Keith cultivars. An increase of radiation resistance of C. capitata eggs was observed as a function of the embryonic development and a Probit 9 of 24.67 Gy was estimated for 48-hour-old eggs in artificial diet. No significant influence of mango fruits was found on the efficacy of irradiation. (author). 11 refs., 3 tabs.

  9. A simple method for preparing artificial larval diet of the West Indian sweetpotato weevil, Euscepes postfasciatus (Fairmaire) (Coleoptera: Curculionidae)

    International Nuclear Information System (INIS)

    Uesato, T.; Kohama, T.

    2008-01-01

    The method for preparing ordinary larval artificial diet for Euscepes postfasciatus (old diet) was complicated and time consuming. Some ingredients (casein, saccharose, salt mixture, etc.) of the diet were added to boiled agar solution, others (vitamin mixture, sweetpotato powder, etc.) were added after the solution was cooled to 55degC. To simplify the diet preparation, we combined all ingredients before mixing with water, and then boiled the solution (new diet). There were no significant differences of survival rate (from egg hatching to adult eclosion) and right elytron length between the weevils reared on the old and new diets, but the development period (from egg to adult) of the weevils fed the new diet was significantly (1.3 days) longer than that of those fed the old diet. Preparation time of the new diet was half that of the old diet. These results suggest that simplified diet preparation can be introduced into the mass-rearing of E. postfasciatus

  10. Food intake in laboratory rats provided standard and fenbendazole-supplemented diets.

    Science.gov (United States)

    Vento, Peter J; Swartz, Megan E; Martin, Lisa Be; Daniels, Derek

    2008-11-01

    The benzimidazole anthelmintic fenbendazole (FBZ) is a common and effective treatment for pinworm infestation in laboratory animal colonies. Although many investigators have examined the potential for deleterious biologic effects of FBZ, more subtle aspects of the treatment remain untested. Accordingly, we evaluated differences in food intake when healthy male Sprague-Dawley rats were provided a standard nonmedicated laboratory rodent chow or the same chow supplemented with FBZ. We also tested for a preference for either food type when subjects were provided a choice of the 2 diets. Data from these experiments showed no differences in food intake or body weight when rats were maintained on either standard or FBZ-supplemented chow. When the rats were given access to both the standard and FBZ-supplemented diets, they showed a clear preference for the standard diet. The preference for the standard diet indicates that the rats can discriminate between the 2 foods and may avoid the FBZ-supplemented chow when possible. Investigators conducting experiments during treatment with FBZ in which differences in food preference are relevant should be aware of these data and plan their studies accordingly.

  11. Use of Tenebrio molitor (Coleoptera: Tenebrionidae) powder to enhance artificial diet formulations for Coleomegilla maculata (Coleoptera: Coccinellidae)

    Science.gov (United States)

    The predatory lady beetle Coleomegilla maculata has potential to control several arthropod pests on crop plants in greenhouses and high tunnels. However, an effective artificial diet is needed in order to mass produce C. maculata in sufficient quantities for augmentative releases. The objectives of ...

  12. Biologia e tabela de vida de fertilidade de Agrotis ipsilon em dieta artificial Biology and fertility life table of Agrotis ipsilon on artificial diet

    Directory of Open Access Journals (Sweden)

    Flavia de Moura Manoel Bento

    2007-10-01

    Full Text Available O objetivo deste trabalho foi desenvolver uma dieta artificial para criação de Agrotis ipsilon em laboratório com base em parâmetros biológicos e na tabela de vida de fertilidade. A dieta artificial utilizada continha feijão, caseína, proteína de soja, levedura e germe de trigo como fontes protéicas. Os parâmetros biológicos duração e viabilidade das fases larval e pupal, peso de pupas, de ambos os sexos, com 24 horas de idade, razão sexual, longevidade dos adultos, período de pré-oviposição e número de ovos produzidos por fêmea e a tabela de vida de fertilidade foram avaliados. Foram observados seis ínstares larvais com duração de 25,4 dias e viabilidade de 93%. A duração da fase pupal foi de 12,4 dias e viabilidade de 96%. A viabilidade de ciclo total foi 72%. O peso de pupas foi 387 mg (machos e 484 mg (fêmeas. A razão sexual foi 0,46. O período de pré-oviposição foi de um dia, com 1.806 ovos por fêmea. Na tabela de vida verificou-se que a taxa líquida de reprodução e a razão finita de aumento foram 616,9 e 1,14, respectivamente. A dieta artificial é adequada à manutenção da criação de A. ipsilon, em laboratório.The objective of this work was to develop an artificial diet to rear Agrotis ipsilon in laboratory using biological parameters and fertility life table. The artificial diet was prepared with bean, casein, soybean protein, yeast and wheat germ as protein sources. The biological aspects duration and viability of larval and pupal stages, pupal weight, sex ratio, life span of adults, preoviposition period, egg laying capacity and fertility life table were evaluated. Six larval instars were observed comprising larval duration of 28,4 days and 93% of viability mean pupal duration of 12,4 days and viability of 96%. The total viability of the life cycle was 72%. The pupae weight was 387 mg for males and 484 mg for females. The sex ratio was 0,46 and the preoviposition period lasted one day and egg

  13. Growth, food consumption, and energy status of juvenile pallid sturgeon fed natural or artificial diets

    Science.gov (United States)

    Meyer, Hilary A.; Chipps, Steven R.; Graeb, Brian D. S.; Klumb, Robert A.

    2016-01-01

    Stocking of hatchery-raised fish is an important part of the pallid sturgeon Scaphirhynchus albus recovery program. In the wild, juvenile pallid sturgeon consume primarily aquatic insects, although little is known about specific dietary needs. In hatchery settings, pallid sturgeon are fed commercial diets that are formulated for salmonids. To compare food consumption, growth, and energy status of pallid sturgeon fed artificial or natural diets, we conducted a laboratory study using 24 juvenile pallid sturgeon (initial fork length 153–236 mm). Pallid sturgeon were fed a daily ration of either commercial pellets (1 mm, slow sinking; 45% protein, 19% fat) or chironomid larvae for 5 wk. Natural-fed pallid sturgeon exhibited a greater specific growth rate (2.12% d−1) than pellet-fed fish (0.06% d−1). Similarly, relative condition was greater for natural-fed sturgeon (Kn = 1.11) than that observed for pellet-fed fish (Kn = 0.87). In contrast, the hepatosomatic index was significantly higher in pellet-fed fish (2.5%), indicating a high lipid diet compared with natural-fed sturgeon (1.4%). Given the importance of natural diets to fish digestion and growth, it is suggested that a more holistic approach be applied in the development of a practical diet for pallid sturgeon that incorporates attributes of natural prey.

  14. Artificial Hydration and Nutrition

    Science.gov (United States)

    ... Crisis Situations Pets and Animals myhealthfinder Food and Nutrition Healthy Food Choices Weight Loss and Diet Plans ... Your Health Resources Healthcare Management Artificial Hydration and Nutrition Artificial Hydration and Nutrition Share Print Patients who ...

  15. Replacing of live food with artificial diet on growth and survival rates of white leg shrimp (Litopenaeus vannamei) larvae

    OpenAIRE

    Ghorbani Vagheie, R.; Matinfar, A.; Aeinjamshid, Kh.; Hafezieh, M.; Ghorbani, R.

    2011-01-01

    Replacing live food with artificial diets in aquatic larviculture, especially in shrimp larvae not only is caused convenience feeding, but also in economical view is very important. With this object, in this survey, a density of 100.L -1 white leg shrimp larvae in 9 nutritional treatments each with three replicates were cultured in 20L tanks each one was held with 10L of 30% salty water using one air stone. The larvae were fed 4 times.day-1 with different diets, including live foods (Cheatoce...

  16. Selection of diet for culture of juvenile silver pomfret, Pampus argenteus

    Science.gov (United States)

    Peng, Shiming; Shi, Zhaohong; Yin, Fei; Sun, Peng; Wang, Jiangang

    2012-03-01

    Juvenile silver pomfret, Pampus argenteus, was grown in culture tanks for 9 weeks on four different diets, and their effects on fish growth, digestive enzyme activity, and body composition were assessed. The feeding regime was as follows: Diet 1: fish meat; Diet 2: fish meat+artificial feed; Diet 3: fish meat+artificial feed+Agamaki clam meat; Diet 4: fish meat+artificial feed+Agamaki clam+copepods. The greatest weight gain was associated with Diet 4, while the lowest weight gain was associated with Diet 1. No significant difference was observed in weight gain between fish receiving Diet 2 and Diet 3. Specific growth rate followed similar trends as weight gain. The feed conversion ratio (FCR) of fish fed Diet 1 was significantly higher than the other fish groups, but no significant differences were observed in FCRs of fish fed Diet 2, Diet 3 or Diet 4. There was also no significant difference in the hepatosomatic index (HSI) between the four diets. For fish that received Diets 2-4, containing artificial feed, higher protease activities were detected. A higher lipid content of the experimental diets also significantly increased lipase activities and body lipid content. No significant differences in amylase activity or body protein content were found between Diets 1-4. In conclusion, a variety of food components, including copepods and artificial feed, in the diet of silver pomfret significantly increased digestive enzyme activity and could improve growth performance.

  17. Biological aspects of Argyrotaenia sphaleropa (Meyrick, 1909) (Lepidoptera: Tortricidae) in artificial diets with different protein sources

    International Nuclear Information System (INIS)

    Manfredi-Coimbra, Silvana; Garcia, Mauro Silveira; Loeck, Alci Enimar; Foresti, Josemar

    2005-01-01

    Biology aspects of Argyrotaenia sphaleropa Meyrick fed on artificial diets with different protein sources were studied: D1-white bean, wheat germ, soybean protein and casein; D2-common bean and yeast and D3-common bean, yeast and wheat germ, evaluating the duration and viability of all developmental stages (egg, larval, prepupa and pupa) and of the total cycle (egg-adult), sex ratio, pupa weight, fecundity, longevity and life table of fertility. Tests were conducted in the laboratory at 25 ± 1 deg C, 65 ±10% RH and 14h of photophase. Duration of the egg stage was 6.6 days on all diets. The longest duration of larval and prepupal stages on D1 and pupal stages on D2, resulting in a longer duration of the total cycle on these two diets (30,9 and 30,8 days). The total viability was higher than 62% on all diets, and there was no statistical difference among the treatments. The number of instars was four or five on all treatments. The lowest fecundity was observed in D1. Based on the fertility life table, D3 was the most suitable diet for rearing A. sphaleropa, due to the lowest development time (T), the highest finite increasing rate (l), and total viability exceeding 75%. (author)

  18. Growth and Reproduction of Artificially Fed Cnaphalocrocis medinalis

    Directory of Open Access Journals (Sweden)

    Jian XU

    2012-09-01

    Full Text Available The growth and reproduction of rice leaffolder, Cnaphalocrocis medinalis, fed on an artificial diet were studied. The results showed that the larvae were able to grow and pupate on the artificial diet. The durations of larvae and pupas of C. medinalis on the artificial diet were 28.1 d and 10.1 d, postponed 4.9 d and 1.7 d respectively, compared with those reared with rice leaves. The number of ovipositions was 41.6 per female, 26.2% higher than that fed on rice leaves. Survival rate curve of larvae was a descent function of mortality-age, with no significant differences from the curve of larvae fed on rice leaves. The net reproductive rate (Ro, intrinsic rate of increase (rm and finite rate of increase (λ of the population fed on diet were 17.6928, 0.0884 and 1.0924, respectively, and the mean generation time (T and double time (td were prolonged 4.9 d and 1.3 d in comparison with the treatment of rice leaves. Population trend index (I was 3.26, indicating a growing number of the population of C. medinalis fed on artificial diet.

  19. Small crumbled diet versus powdered diet in restricted feeding management of juvenile Nile tilapia - doi: 10.4025/actascianimsci.v35i2.16767

    Directory of Open Access Journals (Sweden)

    José Nacélio Oliveira-Segundo

    2013-03-01

    Full Text Available Normal 0 21 false false false MicrosoftInternetExplorer4 The pellet size of the diet can affect both fish growth performance and the water quality of the rearing units. The present work assessed the effects of feeding juvenile Nile tilapia, Oreochromis niloticus (L. a small crumbled diet (SCD; 0.8 mm on water quality and growth performance. Fish were reared for six weeks in twenty 250-L polyethylene outdoor tanks at a density of 10 juveniles tank-1 (40 fish m-3. There were two feeding rates (standard and restricted and two types of artificial fish diet (powdered and SCD. The standard feeding rates were reduced by 30% for restricted feeding. The concentrations of free CO2, reactive phosphorus, total ammonia nitrogen (TAN and nitrite were higher in the full-fed tanks relative to the restricted-fed tanks. In the standard feeding rate groups, those tanks fed SCD had lower TAN and nitrite concentrations than tanks fed a powdered diet. The final body weight and specific growth rate of fish fed a restricted SCD were higher than the full-fed tanks. The higher levels of food waste in the powdered-diet tanks lead to impairment of fish growth performance.  

  20. Development of the design of standardized units for the production of artificial radionuclides

    International Nuclear Information System (INIS)

    Auger, J.P.

    1976-01-01

    The production of artificial radionuclides began more than 20 years ago and has seen continuous growth at the rate over 20% a year. Technology has had to be adapted constantly to this growth in order to guarantee production and at the same time ensure the safety of personnel. The Department, which started its career in underground workings at Chatillon and then moved to the Saclay hot laboratories, is now housed in a building designed specially for the production of artificial radionuclides and equipped with standard production units. The first generation of standard units was sufficient to handle production which had begun to grow. Subsequently, thanks to the experience gained, there came into being a second generation of standardized units perfectly adapted to the new production requirements. The paper describes the evolution of design solutions between the first and the second standard, relating to contained cells, cell containment, remote control, interchangeability of cells, ventilation, waste discharge systems and repair of internal equipment. A highly positive evaluation can be made of the experience gained from the present standard. (author)

  1. Observations on the growth parameters of Spilosoma obliqua (Lepidoptera: Arctiidae) reared on artificial diets and reproductive competence of this irradiated pest and its progeny

    International Nuclear Information System (INIS)

    Rahman, R.; Rahman, M.M.; Islam, S.; Huque, R.

    2002-01-01

    Ten trials were conducted to standardize an artificial diet for Spilosoma oblique. The main ingredients included agar, mulberry leaves, yeast, casein, cellulose, sucrose, glucose, ascorbic acid, sorbic acid, antibiotics, vitamin C, Wesson's salt, and vitamin B complex in variable proportions. A diet formulation with increased amounts of Wesson's salt, choline chloride and iron supplement was found to be most suitable when growth parameters were measured. The deleterious effects when 6-day old pupae were treated with 100 and 150 Gy of gamma radiation were increased in the F 1 generation as compared to the parental generation. Various combinations of crosses between treated and untreated moths indicated that females were more sensitive to gamma radiation when compared to males. F 1 sterility was attained when male moths treated with 100 Gy were allowed to mate with untreated females. Two species of hymenopteran parasitoids of the genus Glyptapanteles and Meteorus were found to infest Spilosoma obliqua. These parasitoids may serve as an effective addition to an integrated pest management program for this pest in Bangladesh. (author)

  2. The distorting effect of varying diets on fecal glucocorticoid measurements as indicators of stress

    DEFF Research Database (Denmark)

    Kalliokoski, Otto; Teilmann, A. Charlotte; Abelson, Klas S. P.

    2015-01-01

    The physiological stress response is frequently gauged in animals, non-invasively, through measuring glucocorticoids in excreta. A concern with this method is, however, the unknown effect of variations in diets on the measurements. With an energy dense diet, leading to reduced defecation, will low...... concentrations of glucocorticoids be artificially inflated? Can this effect be overcome by measuring the total output of glucocorticoids in excreta? In a controlled laboratory setting we explored the effect in mice. When standard mouse chow – high in dietary fiber – was replaced with a 17% more energy-dense diet...

  3. Development of nutrition standards and therapeutic diet specifications for public hospitals in New South Wales.

    Science.gov (United States)

    Williams, Peter; Hazlewood, Tanya; Pang, Glen

    2014-09-01

    In New South Wales (NSW), a new suite of nutrition standards for menus and specifications for therapeutic diets to be used in hospitals has been developed. These standards were required to facilitate centralised menu planning and food production, with the move to management of most hospital food services by HealthShare NSW, a state-wide business unit of NSW Health. The standards also aim to improve communication between health professionals, particularly with the increasing use of computerised meal-ordering systems. Nutrition standards have been developed for adult, paediatric and mental health inpatients, and specifications for 147 different adult and paediatric therapeutic diets. There is still significant variation in the nutrition standards for nutrition and therapeutic diets in hospitals across the Australian states, and a move to a more nationally harmonised approach would be welcome. Further research is required to examine the impact of these standards on operating efficiency and patient care outcomes.

  4. Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report

    Directory of Open Access Journals (Sweden)

    Servadei Franco

    2010-04-01

    Full Text Available Abstract Background Management of glioblastoma multiforme (GBM has been difficult using standard therapy (radiation with temozolomide chemotherapy. The ketogenic diet is used commonly to treat refractory epilepsy in children and, when administered in restricted amounts, can also target energy metabolism in brain tumors. We report the case of a 65-year-old woman who presented with progressive memory loss, chronic headaches, nausea, and a right hemisphere multi-centric tumor seen with magnetic resonance imaging (MRI. Following incomplete surgical resection, the patient was diagnosed with glioblastoma multiforme expressing hypermethylation of the MGMT gene promoter. Methods Prior to initiation of the standard therapy, the patient conducted water-only therapeutic fasting and a restricted 4:1 (fat: carbohydrate + protein ketogenic diet that delivered about 600 kcal/day. The patient also received the restricted ketogenic diet concomitantly during the standard treatment period. The diet was supplemented with vitamins and minerals. Steroid medication (dexamethasone was removed during the course of the treatment. The patient was followed using MRI and positron emission tomography with fluoro-deoxy-glucose (FDG-PET. Results After two months treatment, the patient's body weight was reduced by about 20% and no discernable brain tumor tissue was detected using either FDG-PET or MRI imaging. Biomarker changes showed reduced levels of blood glucose and elevated levels of urinary ketones. MRI evidence of tumor recurrence was found 10 weeks after suspension of strict diet therapy. Conclusion This is the first report of confirmed GBM treated with standard therapy together with a restricted ketogenic diet. As rapid regression of GBM is rare in older patients following incomplete surgical resection and standard therapy alone, the response observed in this case could result in part from the action of the calorie restricted ketogenic diet. Further studies are needed

  5. Sucrose compared with artificial sweeteners

    DEFF Research Database (Denmark)

    Sørensen, Lone Brinkmann; Vasilaras, Tatjana H; Astrup, Arne

    2014-01-01

    There is a lack of appetite studies in free-living subjects supplying the habitual diet with either sucrose or artificially sweetened beverages and foods. Furthermore, the focus of artificial sweeteners has only been on the energy intake (EI) side of the energy-balance equation. The data are from...

  6. Identification of Enterococcus mundtii as a pathogenic agent involved in the "flacherie" disease in Bombyx mori L. larvae reared on artificial diet.

    Science.gov (United States)

    Cappellozza, Silvia; Saviane, Alessio; Tettamanti, Gianluca; Squadrin, Marta; Vendramin, Elena; Paolucci, Paolo; Franzetti, Eleonora; Squartini, Andrea

    2011-03-01

    Enterococcus mundtii was shown to be directly correlated with flacherie disease of the silkworm larvae reared on artificial diet supplemented with chloramphenicol. Its identification was carried out by means of light and electron microscopy and nucleotide sequencing of 16S gene. The bacterium is capable of rapidly multiplying in the silkworm gut and of invading other body tissues, as demonstrated by deliberate infection of germfree larvae and by subsequent TEM observations. E. mundtii can endure alkaline pH of the silkworm gut and it has been proved to adapt in vitro to commonly applied doses of chloramphenicol, whose use can further contribute to reduce competition by other bacteria in Bombyx mori alimentary canal. The modality of transmission of the infection to the larvae was among the objectives of the present research. Since contamination of the progeny by mother moths can be avoided through routine egg shell disinfection, a trans-ovarian vertical transmission can be ruled out. On the other hand the bacterium was for the first time identified on mulberry leaves, and therefore artificial diet based on leaf powder could be a source of infection. We showed that while microwaved diet could contain live E. mundtii cells, the autoclaved diet is safe in this respect. Being E. mundtii also part of the human-associated microbiota, and since B. mori is totally domestic species, a possible role of man in its epidemiology can be postulated. Copyright © 2010 Elsevier Inc. All rights reserved.

  7. Measurement of artificial radionuclides in whole diets around the BNF plc reprocessing plant at Sellafield, Cumbria

    International Nuclear Information System (INIS)

    Mondon, K.J.; Walters, B.

    1993-01-01

    The Ministry of Agriculture, Fisheries and Food has conducted a duplicate diet study around the BNF reprocessing plant of Sellafield in Cumbria. Samples were collected from adults and children. The results of analyses for a number of artificial radionuclides are reported; dose calculations using actual food intakes have also been made. Samples were obtained in both winter (phase 1) and summer (phase 11), between which times the Chernobyl accident occurred, making site-specific dose assessment from caesium isotopes difficult in summer samples. Control diets were collected from a coastal area in Lancashire. Average annual doses based on pre-Chernobyl sampling ranged from 2 μSv in control children to 14 μSv in study adults. This range increased to 9-50 μSv in the second phase of the study. Maximum individual doses were 86 μSv in phase 1 and 102 μ in phase 11, these being well within the government's target dose for members of the public. (author)

  8. Food consumption by Chilo partellus (Lepidoptera: Pyralidae) larvae infected with Beauveria bassiana and Metarhizium anisopliae and effects of feeding natural versus artificial diets on mortality and mycosis.

    Science.gov (United States)

    Tefera, Tadele; Pringle, K L

    2003-11-01

    Second and third instar Chilo partellus larvae were infected with Beauveria bassiana and Metarhizium anisopliae (both at 1x10(8)conidia/ml) and daily consumption of maize leaves was measured. Infection by the fungi was associated with reduced mean daily food consumption. Reduction in food consumption became evident 3-4 days after treatment with the fungi for second instar larvae and 4-5 days for third instar larvae. Four conidial concentrations, 1x10(5), 1x10(6), 1x10(7), and 1x10(8)conidia/ml, were tested against second instar larvae. Food consumption dropped by 70-85% when the second instar larvae were treated with the fungi at 1x10(8)conidia/ml. Reduction in food consumption by C. partellus larvae infected with B. bassiana and M. anisopliae may offset the slow speed of kill of the fungi. The effect of artificial versus natural diets on mortality and mycoses of second instar larvae treated with the fungi at 1x10(8)conidia/ml was determined. Larvae provided with artificial diet suffered little mortality and mycoses than larvae provided with maize leaves. The LT(50) was longer for larvae provided with artificial diet.

  9. Differences in Weight Loss Between Persons on Standard Balanced vs Nutrigenetic Diets in a Randomized Controlled Trial.

    Science.gov (United States)

    Frankwich, Karen A; Egnatios, Jeremy; Kenyon, Mandy L; Rutledge, Thomas R; Liao, Patricia S; Gupta, Samir; Herbst, Karen L; Zarrinpar, Amir

    2015-09-01

    Many companies provide genetic tests for obesity-related polymorphisms (nutrigenetics) and make dietary recommendations for weight loss that are based on the results. We performed a randomized controlled trial to determine whether more participants who followed a nutrigenetic-guided diet lost ≥5% of their body weight than participants on a standard balanced diet for 8 and 24 weeks. We performed a prospective study of 51 obese or overweight U.S. veterans on an established weight management program at the Veterans Administration San Diego Healthcare System (the MOVE! program). Participants were randomly assigned to groups placed on a nutrigenetic-guided diet (balanced, low-carbohydrate, low-fat, or Mediterranean; n = 30) or a standard balanced diet (n = 21). Nutrigenetic diets were selected on the basis of results from the Pathway FIT test. There was no significant difference in the percentage of participants on the balanced diet vs the nutrigenetic-guided diet who lost 5% of their body weight at 8 weeks (35.0% ± 20.9% vs 26.9% ± 17.1%, respectively; P = .28) or at 24 weeks. Both groups had difficulty adhering to the diets. However, adherence to the nutrigenetic-guided diet correlated with weight loss (r = 0.74; P = 4.0 × 10(-5)), but not adherence to standard therapy (r = 0.34; P = .23). Participants who had low-risk polymorphisms for obesity lost more weight than all other participants at 8 weeks (5.0% vs 2.9%, respectively; P = .02) and had significantly greater reductions in body mass index (6.4% vs 3.6%, respectively; P = .03) and waist circumference (6.5% vs 2.6%, respectively; P = .02) at 24 weeks. In a prospective study, a nutrigenetic-based diet did not increase weight loss compared with a standard balanced diet. However, genetic features can identify individuals most likely to benefit from a balanced diet weight loss strategy; these findings require further investigation. ClinicalTrials.gov number: NCT01859403. Copyright © 2015 AGA

  10. Differences in Weight Loss Between Persons on Standard Balanced vs Nutrigenetic Diets in a Randomized Controlled Trial

    Science.gov (United States)

    Kenyon, Mandy L.; Rutledge, Thomas R.; Liao, Patricia S.; Gupta, Samir; Herbst, Karen L.; Zarrinpar, Amir

    2015-01-01

    Background & Aims Many companies provide genetic tests for obesity-related polymorphisms (nutrigenetics) and make dietary recommendations for weight loss based on the results. We performed a randomized controlled trial to determine whether more participants who followed a nutrigenetic-guided diet lost ≥5% of their body weight than participants on a standard balanced diet, for 8 and 24 weeks. Methods We performed a prospective study of 51 obese or overweight US veterans on an established weight management program at the Veterans Administration San Diego Healthcare System (the MOVE! Program). Participants were randomly assigned to groups placed on a nutrigenetic-guided diet (balanced, low-carbohydrate, low-fat, or Mediterranean; n=30) or a standard balanced diet (n=21). Nutrigenetic diets were selected based on results from the Pathway FIT test (Pathway Genomics; San Diego, CA). Results There was no significant difference in the percentage of participants on the balanced diet vs the nutrigenetic-guided diet who lost 5% of their body weight at 8 weeks (35.0%±20.9% vs 26.9%±17.1%, respectively; P=.28) or at 24 weeks. Both groups had difficulty adhering to the diets. However, adherence to the nutrigenetic-guided diet correlated with weight loss (r=0.74; P= 4.0 × 10−5), but not adherence to standard therapy (r=0.34; P=.23). Participants who had low-risk polymorphisms for obesity lost more weight than all other participants at 8 weeks (5.0% vs 2.9%, respectively; P=.02), and had significantly greater reductions in body mass index (6.4% vs 3.6% respectively; P=.03) and waist circumference (6.5% vs 2.6% respectively; P=.02) at 24 weeks. Conclusions In a prospective study, a nutrigenetic-based diet did not increase weight loss compared with a standard balanced diet. However, genetic features can identify individuals most likely to benefit from a balanced diet weight loss strategy; these findings require further investigation. ClincialTrials.gov number: NCT01859403

  11. Substitution time of natural food by artificial diet on survival rate and growth of pacific white shrimp (Litopenaeus vannamei postlarvae during rearing in low salinity media

    Directory of Open Access Journals (Sweden)

    Ferdinand Hukama Taqwa

    2011-01-01

    Full Text Available This research was conducted to determine natural food substitution time by artificial diet   after salinity acclimatization from 20 ppt until 2 ppt, which can increase survival and growth of (Litopenaeus vannamei postlarvae during rearing period. Design experiment was completely randomized design with five treatments and three replications of natural food Chironomus sp.  (60% of crude protein substitution time by artificial diet (40% of crude protein at day: 1 (A, 7 (B, 14 (C, 21 (D and full natural food without artificial diet (E during 28 days rearing period. White shrimp postlarvae and rearing media in this experiment based from best result of earlier research that is PL25 from acclimatization in media 2 ppt with addition of potassium 25 ppm to freshwater media.  The densities of PL25 white shrimp were 20 PLs/50 liters of 2 ppt media. The result of this experiment showed that the use of artificial diet as soon as after salinity acclimatization (PL25 gave best performance production compared to which only that was given natural food Chironomus sp. during experiment or with treatment by artificial diet substitution at day-7, day-14 or day-21, shown with the highest value of food consumption level, protein retention, energy retention, daily growth rate and food efficiency. Survival rate of PL54 was above 80% and not significant different between treatment. That is supported by chemical-physical value of water quality still in range appropriate to survival rate of white shrimp post larvae during a rearing period. The result of this experiment indicated that requirement nutrient of PL25 in low salinity did not fulfilled if only rely on natural food, so that require artificial diet with nutrition content to support growth and survival rate of white shrimp post larvae more maximal. Key words: salinity, natural food, artificial diet, Pacific white shrimp   ABSTRAK Tujuan penelitian ini adalah untuk menentukan waktu penggantian pakan alami oleh

  12. Beneficial effect of low dose Amlodipine vs Nifedipine on serum cholesterol profile of rabbits receiving standard diet.

    Directory of Open Access Journals (Sweden)

    Bavane DS, Rajesh CS, Gurudatta Moharir, Bharatha Ambadasu

    2013-01-01

    Full Text Available To investigate the effect of low dose amlodipine v/s nifedipine on serum cholesterol profile of rabbits receiving standard diet. Methods: Fourty Newzealand rabbits were selected for the study. Their cholesterol profile was estimated at the beginning of the study. Rabbits were grouped into 4 groups receiving standard diet (control group, standard diet + vehicle propylene glycol, standard diet + nifedipine dissolved in propylene glycol and standard diet + amlodipine dissolved in propylene glycol. Along with standard diet they were treated with respective drugs for ten weeks. At the end of ten weeks serum cholesterol profile was estimated. Results: The cholesterol profile was estimated at the beginning and at the end of ten weeks. Total cholesterol in the amlodipine group decreased from 97±4.06 mg/dl to 90±4.2 mg/dl and HDL-Cholesterol increased from 32.01±4.40 mg/dl to 37±4.60 mg/dl after 10 week treatment but these changes were not significant. LDL cholesterol decreased significantly in rabbits with low dose of amlodipine from 55.42±3.32 mg/dl to 32.40±3.22 mg/dl and. In the nifedipine group there was a slight increase in total cholesterol from 102.49±5.16 mg/dl to 106±5.39 mg/dl, HDL cholesterol from 34.10±2.80 to 35.16±2.82 mg/dl and LDL cholesterol also increased from 56.20±2.20 mg/dl to 59.00±2.20 mg/dl after 10 week treatment. Conclusion: The study shows amlodipine produces favorable alterations in serum cholesterol profile

  13. Elemental concentrations in kidney and liver of mice fed with cafeteria or standard diet determined by particle induced X-ray emission

    Energy Technology Data Exchange (ETDEWEB)

    Dimer Leffa, Daniela [Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806-000 Criciúma, SC (Brazil); Iochims dos Santos, Carla Eliete; Debastiani, Rafaela; Amaral, Livio; Yoneama, Maria Lucia; Ferraz Dias, Johnny [Ion Implantation Laboratory, Physics Institute, Federal University of Rio Grande do Sul, Porto Alegre (Brazil); Moraes Andrade, Vanessa, E-mail: vmoraesdeandrade@yahoo.com.br [Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806-000 Criciúma, SC (Brazil)

    2014-01-01

    The importance of trace elements in human health is well known and their main source is daily diet. Nowadays, one of the biggest issues is the presence of these micronutrients in levels much higher than required, leading to potential toxic effects. The aim of this work was to investigate the elemental content in organs of mice fed with cafeteria or standard diet using PIXE. Twelve male Swiss mice were divided into two groups: control group (standard chow) and cafeteria group (high-caloric diet). After 17 weeks, samples of different organs (kidney and liver) were collected and prepared for PIXE analysis. The Fe concentration in kidney and liver was statistically higher in animals that received the cafeteria diet (p < 0.001). The Al and Si kidney contents were significantly higher for cafeteria diet in relation to standard diet (p < 0.05). Moreover, the standard diet showed significant differences for Cl and K (p < 0.05) in comparison to cafeteria diet in kidney, and for P, S and Zn (p < 0.005) in liver.

  14. Elemental concentrations in kidney and liver of mice fed with cafeteria or standard diet determined by particle induced X-ray emission

    International Nuclear Information System (INIS)

    Dimer Leffa, Daniela; Iochims dos Santos, Carla Eliete; Debastiani, Rafaela; Amaral, Livio; Yoneama, Maria Lucia; Ferraz Dias, Johnny; Moraes Andrade, Vanessa

    2014-01-01

    The importance of trace elements in human health is well known and their main source is daily diet. Nowadays, one of the biggest issues is the presence of these micronutrients in levels much higher than required, leading to potential toxic effects. The aim of this work was to investigate the elemental content in organs of mice fed with cafeteria or standard diet using PIXE. Twelve male Swiss mice were divided into two groups: control group (standard chow) and cafeteria group (high-caloric diet). After 17 weeks, samples of different organs (kidney and liver) were collected and prepared for PIXE analysis. The Fe concentration in kidney and liver was statistically higher in animals that received the cafeteria diet (p < 0.001). The Al and Si kidney contents were significantly higher for cafeteria diet in relation to standard diet (p < 0.05). Moreover, the standard diet showed significant differences for Cl and K (p < 0.05) in comparison to cafeteria diet in kidney, and for P, S and Zn (p < 0.005) in liver

  15. Sterol content in the artificial diet of Mythimna separata affects the metabolomics of Arma chinensis (Fallou) as determined by proton nuclear magnetic resonance spectroscopy.

    Science.gov (United States)

    Guo, Yi; Liu, Chen-Xi; Zhang, Li-Sheng; Wang, Meng-Qing; Chen, Hong-Yin

    2017-12-01

    Insects cannot synthesize sterols and must obtain them from plants. Therefore, reducing plant sterol content or changing sterol type might be an effective pest control strategy. However, the impacts of these changes on pests' natural predators remain unknown. Here, we fed artificial diets with reduced sterol content to Mythimna separata (Walker) (Lepidoptera: Noctuidae) and investigated the effects on its natural predator, Arma chinensis (Fallou) (Hemiptera: Pentatomidae). Reduced sterol content in M. separata (MS1, MS2, and MS5) was achieved by feeding them artificial diets prepared from a feed base subjected to one, two, or five cycles of sterol extractions, respectively. The content of most substances increased in A. chinensis (AC) groups feeding on MS2 and MS5. The content of eight substances (alanine, betaine, dimethylamine, fumarate, glutamine, glycine, methylamine, and sarcosine) differed significantly between the control (AC0) and treated (AC1, AC2, and AC5) groups. Metabolic profiling revealed that only AC5 was significantly distinct from AC0; the major substances contributing to this difference were maltose, glucose, tyrosine, proline, O-phosphocholine, glutamine, allantoin, lysine, valine, and glutamate. Furthermore, only two metabolic pathways, that is, nicotinate and nicotinamide metabolism and ubiquinone and other terpenoid-quinone biosynthesis, differed significantly between AC1 and AC5 and the control, albeit with an impact value of zero. Thus, the sterol content in the artificial diet fed to M. separata only minimally affected the metabolites and metabolic pathways of its predator A. chinensis, suggesting that A. chinensis has good metabolic self-regulation with high resistance to sterol content changes. © 2017 Wiley Periodicals, Inc.

  16. Effects of a High-Protein/Low-Carbohydrate Diet versus a Standard Hypocaloric Diet on Weight and Cardiovascular Risk Factors: Role of a Genetic Variation in the rs9939609 FTO Gene Variant.

    Science.gov (United States)

    de Luis, Daniel Antonio; Aller, Rocío; Izaola, Olatz; Primo, David; Urdiales, Silvia; Romero, Enrique

    2015-01-01

    The common polymorphism rs9939609 of the fat mass- and obesity-associated gene (FTO) has been linked to obesity. Our aim was to investigate its role in weight loss after the administration of a high-protein/low-carbohydrate diet compared to a standard hypocaloric diet (1,000 kcal/day). During 9 months, 195 patients were randomly allocated to a high-protein hypocaloric diet (HP diet) and a standard hypocaloric diet (S diet). With the HP diet, BMI (-1.9 ± 1.2 vs. -2.10 ± 1.8; p diet, BMI (-0.9 ± 1.1 vs. -1.8 ± 1.2; p diet and in both genotype groups, glucose, insulin levels, homeostasis model assessment of insulin resistance (HOMA-IR), total cholesterol, triglycerides and low-density lipoprotein (LDL) decreased. With the S diet, total cholesterol and LDL decreased. Weight loss was better in A allele carriers than noncarriers, and metabolic improvement was better with the HP diet. © 2015 S. Karger AG, Basel.

  17. natural or artificial diets

    Directory of Open Access Journals (Sweden)

    A. O. Meyer-Willerer

    2005-01-01

    Full Text Available Se probaron alimentos artificiales y naturales con larva de camarón (Litopenaeus vannamei cultivados en diferentes recipientes. Estos fueron ocho frascos cónicos con 15L, ocho acuarios con 50L y como grupo control, seis tanques de fibra de vidrio con 1500L; todos con agua marina fresca y filtrada. La densidad inicial en todos los recipientes fue de 70 nauplios/L. Aquellos en frascos y acuarios recibieron ya sea dieta natural o artificial. El grupo control fue cultivado con dieta natural en los tanques grandes que utilizan los laboratorios para la producción masiva de postlarvas. El principal producto de excreción de larva de camarón es el ión amonio, que es tóxico cuando está presente en concentraciones elevadas. Se determinó diariamente con el método colorimétrico del indofenol. Los resultados muestran diferencias en la concentración del ión amonio y en la sobrevivencia de larvas entre las diferentes dietas y también entre los diferentes recipientes. En aquellos con volúmenes pequeños comparados con los grandes, se presentó mayor concentración de amonio (500 a 750µg/L, en aquellos con dietas naturales, debido a que este ión sirve de fertilizante a las algas adicionadas, necesitando efectuar recambios diarios de agua posteriores al noveno día de cultivo para mantener este ión a una concentración subletal. Se obtuvo una baja cosecha de postlarvas (menor a 15% con el alimento artificial larvario, debido a la presencia de protozoarios, alimentándose con el producto comercial precipitado en el fondo de los frascos o acuarios. Los acuarios con larvas alimentadas con dieta natural también mostraron concentraciones subletales de amonio al noveno día; sin embargo, la sobrevivencia fue cuatro veces mayor que con dietas artificiales. Los tanques control con dietas naturales presentaron tasas de sobrevivencia (70 ± 5% similares a la reportada por otros laboratorios.

  18. Haloperidol and Rimonabant Increase Delay Discounting in Rats Fed High-Fat and Standard-Chow Diets

    Science.gov (United States)

    Boomhower, Steven R.; Rasmussen, Erin B.

    2016-01-01

    The dopamine and endocannabinoid neurotransmitter systems have been implicated in delay discounting, a measure of impulsive choice, and obesity. The current study was designed to determine the extent to which haloperidol and rimonabant affected delay discounting in rats fed standard-chow and high-fat diets. Sprague-Dawley rats were allowed to free-feed under a high-fat diet (4.73 kcal/g) or a standard-chow diet (3.0 kcal/g) for three months. Then, operant sessions began in which rats (n = 9 standard chow; n = 10 high-fat) chose between one sucrose pellet delivered immediately vs. three sucrose pellets after a series of delays. In another condition, carrot-flavored pellets replaced sucrose pellets. After behavior stabilized, acute injections of rimonabant (0.3-10 mg/kg) and haloperidol (0.003-0.1 mg/kg) were administered i.p. before some choice sessions in both pellet conditions. Haloperidol and rimonabant increased discounting in both groups of rats by decreasing percent choice for the larger reinforcer and area-under-the-curve (AUC) values. Rats in the high-fat diet condition demonstrated increased sensitivity to haloperidol compared to chow-fed controls: haloperidol increased discounting in both dietary groups in the sucrose condition,, but only in the high-fat-fed rats in the carrot-pellet condition. These findings indicate that blocking D2 and CB1 receptors results in increased delay discounting, and that a high-fat diet may alter sensitivity to dopaminergic compounds using the delay-discounting task. PMID:25000488

  19. The variability of standard artificial soils: Behaviour, extractability and bioavailability of organic pollutants

    International Nuclear Information System (INIS)

    Hofman, Jakub; Hovorková, Ivana; Semple, Kirk T.

    2014-01-01

    Highlights: • Artificial soils from different laboratories revealed different fates, behaviour and bioavailability of lindane and phenanthrene. • Lindane behaviour was related to organic carbon. • Phenanthrene behaviour was significantly affected by degrading microorganisms from peat. • Sterilization of artificial soils might reduce unwanted variability. -- Abstract: Artificial soil is an important standard medium and reference material for soil ecotoxicity bioassays. Recent studies have documented the significant variability of their basic properties among different laboratories. Our study investigated (i) the variability of ten artificial soils from different laboratories by means of the fate, extractability and bioavailability of phenanthrene and lindane, and (ii) the relationships of these results to soil properties and ageing. Soils were spiked with 14 C-phenanthrene and 14 C-lindane, and the total residues, fractions extractable by hydroxypropyl-β-cyclodextrin, and the fractions of phenanthrene mineralizable by bacteria were determined after 1, 14, 28 and 56 days. Significant temporal changes in total residues and extractable and mineralizable fractions were observed for phenanthrene, resulting in large differences between soils after 56 days. Phenanthrene mineralization by indigenous peat microorganisms was suggested as the main driver of that, outweighing the effects of organic matter. Lindane total residues and extractability displayed much smaller changes over time and smaller differences between soils related to organic matter. Roughly estimated, the variability between the artificial soils was comparable to natural soils. The implications of such variability for the results of toxicity tests and risk assessment decisions should be identified. We also suggested that the sterilization of artificial soils might reduce unwanted variability

  20. The variability of standard artificial soils: Behaviour, extractability and bioavailability of organic pollutants

    Energy Technology Data Exchange (ETDEWEB)

    Hofman, Jakub, E-mail: hofman@recetox.muni.cz [Research Centre for Toxic Compounds in the Environment (RECETOX), Faculty of Science, Masaryk University, Kamenice 753/5, Brno CZ-62500 (Czech Republic); Hovorková, Ivana [Research Centre for Toxic Compounds in the Environment (RECETOX), Faculty of Science, Masaryk University, Kamenice 753/5, Brno CZ-62500 (Czech Republic); Semple, Kirk T. [Lancaster Environment Centre, Lancaster University, Lancaster LA1 4YQ (United Kingdom)

    2014-01-15

    Highlights: • Artificial soils from different laboratories revealed different fates, behaviour and bioavailability of lindane and phenanthrene. • Lindane behaviour was related to organic carbon. • Phenanthrene behaviour was significantly affected by degrading microorganisms from peat. • Sterilization of artificial soils might reduce unwanted variability. -- Abstract: Artificial soil is an important standard medium and reference material for soil ecotoxicity bioassays. Recent studies have documented the significant variability of their basic properties among different laboratories. Our study investigated (i) the variability of ten artificial soils from different laboratories by means of the fate, extractability and bioavailability of phenanthrene and lindane, and (ii) the relationships of these results to soil properties and ageing. Soils were spiked with {sup 14}C-phenanthrene and {sup 14}C-lindane, and the total residues, fractions extractable by hydroxypropyl-β-cyclodextrin, and the fractions of phenanthrene mineralizable by bacteria were determined after 1, 14, 28 and 56 days. Significant temporal changes in total residues and extractable and mineralizable fractions were observed for phenanthrene, resulting in large differences between soils after 56 days. Phenanthrene mineralization by indigenous peat microorganisms was suggested as the main driver of that, outweighing the effects of organic matter. Lindane total residues and extractability displayed much smaller changes over time and smaller differences between soils related to organic matter. Roughly estimated, the variability between the artificial soils was comparable to natural soils. The implications of such variability for the results of toxicity tests and risk assessment decisions should be identified. We also suggested that the sterilization of artificial soils might reduce unwanted variability.

  1. Evaluation of NASA Foodbars as a Standard Diet for Use in Short-Term Rodent Space Flight Studies

    Science.gov (United States)

    Tou, Janet; Grindeland, Richard; Barrett, Joyce; Dalton, Bonnie; Mandel, Adrian; Wade, Charles

    2003-01-01

    A standard rodent diet for space flight must meet the unique conditions imposed by the space environment and must be nutritionally adequate since diet can influence the outcome of experiments. This paper evaluates the use of National Aeronautics and Space Administration (NASA) developed Foodbars as a standard space flight diet for rats. The Foodbar's semi-purified formulation permits criteria such as nutrient consistency, high nutrient bioavailability and flexibility of formulation to be met. Extrusion of the semi-purified diet produces Foodbars with the proper texture and a non-crumbing solid form for use in space. Treatment of Foodbar with 0.1% potassium sorbate prevents mold growth. Irradiation (15-25 kGy) prevents bacterial growth and in combination with sorbate-treatment provides added protection against mold for shelf-stability. However, during the development process, nutrient analyses indicated that extrusion and irradiation produced nutrient losses. Nutrients were adjusted accordingly to compensate for processing losses. Nutrient analysis of Foodbars continues to be performed routinely to monitor nutrient levels. It is important that the standard rodent diet provide nutrients that will prevent deficiency but also avoid excess that may mask physiological changes produced by space flight. All vitamins levels in the Foodbars, except for vitamin K conformed to or exceeded the current NRC (1995) recommendations. All indispensable amino acids in Foodbar conformed to or exceeded the NRC nutrient recommendation for mice growth and rat maintenance. However, some indispensable amino acids were slightly below recommendations for rat reproduction/growth. Short-term (18-20 d) animal feeding studies indicated that Foodbars were palatable, supported growth and maintained health in rats. Results indicated that NASA rodent Foodbars meet both the physical and nutritional criteria required to support rodents in the space environment and thus, may be used successfully as a

  2. Comparison of several artificial diets with different protein sources for massal rearing of Ecdytolopha aurantiana (Lima) (Lepidoptera: Tortricidae); Comparacao de dietas artificiais, com fontes proteicas variaveis, para criacao de Ecdytolopha aurantiana (Lima) (Lepidoptera: Tortricidae)

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, Mauro S. [Universidade Federal de Pelotas (UFPel), RS (Brazil). Dept. de Fitossanidade; Parra, Jose R.P. [Universidade de Sao Paulo (USP), Piracicaba, SP (Brazil). Escola Superior de Agricultura Luiz de Queiroz (ESALQ). Dept. de Entomologia

    1999-06-15

    The development of Ecdytolopha aurantiana (Lima) was compared among four artificial diets with different protein sources based on biological characteristics and fertility life table in order to have the insect available throughout the year for research in different areas. All diets with variable protein sources (D1= bean, yeast, wheat germ, soybean protein and casein; D2= corn flour, wheat germ, and yeast; D3= soybean protein, and wheat germ; D4= bean, yeast and wheat germ) allowed the insect to developed at 27 +- 2 deg C; RH 65 +- 10% and 14 h photophase. In all diets the insect presented four instars with several other similar biological characteristics. Since diet D2 (corn flour, wheat germ and yeast) provided the lowest development time, the highest viability, a high value of finite ratio of increase (ll), besides being of low cost and easy preparation, it can be considered as the most adequate for laboratory rearing of E. aurantiana. Balanced nutrients showed more important than the nutritional value of the components of the diet for this insect which is, for the first time, fed on artificial diet. (author)

  3. Changes in energy content of Podisus maculiventris (Say (Hemiptera: Pentatomidae in response to different diets

    Directory of Open Access Journals (Sweden)

    Seyed Mohammad Ahsaei

    2014-12-01

    Full Text Available Nymphal instars and adults of the spined soldier bug, Podisus maculiventris, preferably feed on lepidopteran and colopteran larvae. Different prey diets can change fitness including energy reservoirs of the predator. In the present study, effects of different artificial and natural diets as well as starvation was studied on energy contents of the third and fourth nymphal instars of P. maculiventris. Total available energy calculated as the sum of the energy contents of lipids, carbohydrates, glycogen, and proteins did not significantly differ in the third and fourth nymphal instars fed on natural and artificial diets. Among the energy reservoirs, only total lipid storage of the starved nymphal instars was significantly different from that in the bugs fed on the natural diet. In conclusion, total energy reserves cannot be changed in response to artificial diet. A better understanding of the impact of artificial diets on the energy reserves of natural enemies can be considered as a biomarker for more appropriate mass rearing approaches of natural enemies.

  4. Effects of ethanol on CYP2E1 levels and related oxidative stress using a standard balanced diet.

    Science.gov (United States)

    Azzalis, Ligia A; Fonseca, Fernando L A; Simon, Karin A; Schindler, Fernanda; Giavarotti, Leandro; Monteiro, Hugo P; Videla, Luis A; Junqueira, Virgínia B C

    2012-07-01

    Expression of cytochrome P4502E1 (CYP2E1) is very much influenced by nutritional factors, especially carbohydrate consumption, and various results concerning the expression of CYP2E1 were obtained with a low-carbohydrate diet. This study describes the effects of ethanol treatment on CYP2E1 levels and its relationship with oxidative stress using a balanced standard diet to avoid low or high carbohydrate consumption. Rats were fed for 1, 2, 3, or 4 weeks a commercial diet plus an ethanol-sucrose solution. The results have shown that ethanol administration was associated with CYP2E1 induction and stabilization without related oxidative stress. Our findings suggest that experimental models with a low-carbohydrate/high-fat diet produce some undesirable CYP2E1 changes that are not present when a balanced standard diet is given.

  5. Dietary intake of ain-93 standard diet induces Fatty liver with altered hepatic fatty acid profile in Wistar rats.

    Science.gov (United States)

    Farias Santos, Juliana; Suruagy Amaral, Monique; Lima Oliveira, Suzana; Porto Barbosa, Júnia; Rego Cabral, Cyro; Sofia Melo, Ingrid; Bezerra Bueno, Nassib; Duarte Freitas, Johnatan; Goulart Sant'ana, Antônio; Rocha Ataíde, Terezinha

    2015-05-01

    There are several standard diets for animals used in scientific research, usually conceived by scientific institutions. The AIN-93 diet is widely used, but there are some reports of fatty liver in Wistar rats fed this diet. We aimed to evaluate the hepatic repercussions of the AIN-93 diet intake in Wistar rats. Forty newly-weaned 21-day-old male Wistar rats were fed either the AIN-93 diet or a commercial diet for either 1 month or 4 months. Weight gain, serum biochemistry, hepatic histology, and hepatic fatty acid profile were analyzed. Hepatic steatosis was observed, especially in the group fed the AIN-93 diet. Serum blood glucose, absolute and relative liver weight and hepatic levels of oleic, palmitoleic, stearic, and palmitic fatty acids were related to the observed steatosis, while lipidogram and serum markers of liver function and injury were not. AIN-93 diet induced acute hepatic steatosis in Wistar rats, which may compromise its use as a standard diet for experimental studies with rodents. The hepatic fatty acid profile was associated with steatosis, with possible implications for disease prognosis. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  6. Diet Affects Muscle Quality and Growth Traits of Grass Carp (Ctenopharyngodon idellus): A Comparison Between Grass and Artificial Feed.

    Science.gov (United States)

    Zhao, Honghao; Xia, Jianguo; Zhang, Xi; He, Xugang; Li, Li; Tang, Rong; Chi, Wei; Li, Dapeng

    2018-01-01

    Fish muscle, the main edible parts with high protein level and low fat level, is consumed worldwide. Diet contributes greatly to fish growth performance and muscle quality. In order to elucidate the correlation between diet and muscle quality, the same batch of juvenile grass carp ( Ctenopharyngodon idellus ) were divided into two groups and fed with either grass ( Lolium perenne, Euphrasia pectinata and Sorghum sudanense ) or artificial feed, respectively. However, the different two diets didn't result in significant differences in all the detected water quality parameters (e.g., Tm, pH, DO, NH 3 /[Formula: see text]-N, [Formula: see text]-N, [Formula: see text], TN, TP, and TOC) between the two experimental groups. After a 4-month culture period, various indexes and expression of myogenic regulatory factor (MRFs) and their related genes were tested. The weight gain of the fish fed with artificial feed (AFG) was nearly 40% higher than the fish fed with grass (GFG). Significantly higher alkaline phosphatase, total cholestrol, high density cholestrol and total protein were detected in GFG as compared to AFG. GFG also showed increased hardness, resilience and shear force in texture profile analysis, with significantly bigger and compact muscle fibers in histologic slices. The fat accumulation was most serious in the abdomen muscle of AFG. Additionally, the expression levels of MyoG, MyoD, IGF - 1 , and MSTNs were higher, whereas Myf - 5, MRF4 , and IGF -2 were lower in most positional muscles of GFG as compared to AFG. Overall, these results suggested that feeding grass could promote muscle growth and development by stimulating muscle fiber hypertrophy, as well as significantly enhance the expression of CoL1A s. Feeding C. idellus with grass could also improve flesh quality by improving muscle characteristics, enhancing the production of collagen, meanthile, reducing fat accumulation and moisture in muscle, but at the cost of a slower growth.

  7. Diet Affects Muscle Quality and Growth Traits of Grass Carp (Ctenopharyngodon idellus: A Comparison Between Grass and Artificial Feed

    Directory of Open Access Journals (Sweden)

    Honghao Zhao

    2018-03-01

    Full Text Available Fish muscle, the main edible parts with high protein level and low fat level, is consumed worldwide. Diet contributes greatly to fish growth performance and muscle quality. In order to elucidate the correlation between diet and muscle quality, the same batch of juvenile grass carp (Ctenopharyngodon idellus were divided into two groups and fed with either grass (Lolium perenne, Euphrasia pectinata and Sorghum sudanense or artificial feed, respectively. However, the different two diets didn't result in significant differences in all the detected water quality parameters (e.g., Tm, pH, DO, NH3/NH4+-N, NO3--N, NO2-, TN, TP, and TOC between the two experimental groups. After a 4-month culture period, various indexes and expression of myogenic regulatory factor (MRFs and their related genes were tested. The weight gain of the fish fed with artificial feed (AFG was nearly 40% higher than the fish fed with grass (GFG. Significantly higher alkaline phosphatase, total cholestrol, high density cholestrol and total protein were detected in GFG as compared to AFG. GFG also showed increased hardness, resilience and shear force in texture profile analysis, with significantly bigger and compact muscle fibers in histologic slices. The fat accumulation was most serious in the abdomen muscle of AFG. Additionally, the expression levels of MyoG, MyoD, IGF-1, and MSTNs were higher, whereas Myf-5, MRF4, and IGF-2 were lower in most positional muscles of GFG as compared to AFG. Overall, these results suggested that feeding grass could promote muscle growth and development by stimulating muscle fiber hypertrophy, as well as significantly enhance the expression of CoL1As. Feeding C. idellus with grass could also improve flesh quality by improving muscle characteristics, enhancing the production of collagen, meanthile, reducing fat accumulation and moisture in muscle, but at the cost of a slower growth.

  8. Variability of standard artificial soils: Physico-chemical properties and phenanthrene desorption measured by means of supercritical fluid extraction

    International Nuclear Information System (INIS)

    Bielská, Lucie; Hovorková, Ivana; Komprdová, Klára; Hofman, Jakub

    2012-01-01

    The study is focused on artificial soil which is supposed to be a standardized “soil like” medium. We compared physico-chemical properties and extractability of Phenanthrene from 25 artificial soils prepared according to OECD standardized procedures at different laboratories. A substantial range of soil properties was found, also for parameters which should be standardized because they have an important influence on the bioavailability of pollutants (e.g. total organic carbon ranged from 1.4 to 6.1%). The extractability of Phe was measured by supercritical fluid extraction (SFE) at harsh and mild conditions. Highly variable Phe extractability from different soils (3–89%) was observed. The extractability was strongly related (R 2 = 0.87) to total organic carbon content, 0.1–2 mm particle size, and humic/fulvic acid ratio in the following multiple regression model: SFE (%) = 1.35 * sand (%) − 0.77 * TOC (%)2 + 0.27 * HA/FA. - Highlights: ► We compared properties and extractability of Phe from 25 different artificial soils. ► Substantial range of soil properties was found, also for important parameters. ► Phe extractability was measured by supercritical fluid extraction (SFE) at 2 modes. ► Phe extractability was highly variable from different soils (3–89%). ► Extractability was strongly related to TOC, 0.1–2 mm particles, and HA/FA. - Significant variability in physico-chemical properties exists between artificial soils prepared at different laboratories and affects behavior of contaminants in these soils.

  9. Cadmium contamination in cereal-based diets and diet ingredients

    International Nuclear Information System (INIS)

    Siitonen, P.H.; Thompson, H.C. Jr.

    1990-01-01

    Cereal-based diet and/or diet ingredient cadmium levels were determined by graphite furnace AAS. Cadmium contamination was 88.3 and 447 ppb in two cereal-based diets, 44.6 and 48.9 ppb in two purified diets, and ranged from less than 1.1 to 22,900 ppb in the ingredients of one cereal-based diet. The major source of cadmium contamination was attributed to the calcium supplement used for diet formulation. Comparative analyses of two purified diet samples and one cereal-based diet by the National Institute of Standards and Technology (NIST, formerly the National Bureau of Standards) and the National Center for Toxicological Research (NCTR) gave virtually identical results for Cd. A comparative study of Cd levels determined by flame and furnace AAS was also made by the NCTR and the NIST

  10. The Response of Iraqi buffaloes to standardized diet

    Directory of Open Access Journals (Sweden)

    J.M. Khlef

    2010-02-01

    Full Text Available This Experiment was conducted in the Newashi village of Thiqar province in the south of Iraq from 15 October till 31 December 2006. A sample of 50 milking buffaloes in 1st to 7th lactation were randomly choosed in three nearby herds , then divided into two equal groups for the treatment and the control. After 10 days of adaptation, the treated group was fed the standardized diet which was consisted of: Alfa Alfa hay ,12 kg/day, concentrates, 8 kg/day. The concentrate consists of barley grains 37%, maize grain 15%, wheat bran 40%, rice bran 5%,calcium carbonate 2% and food salt 1% .The control group was fed -as it is usual in the region –reed roughages , rice straws, dray bred and some wheat bran. Daily milk yield for the whole sample, cream( ghiamer and fat percent rom randomly choosed individuals from each group were measured . Simple linear model was used to detect the effect of the lactation, herd, calf sex and milking time on the traits . Duncan test was used to compare the differences between means . The results obtained showed that the lactation , herd, sex of calf and milking time had significant effect on the traits (p< 0.001. The diet had significantly affected daily milk yield , cream and fat percent ( 8.40 ± 1.75 vis 5.67 ± 1.41,21± 6.6 vis 9.79 3.24, and 12.4.11 vis 5.88±1.95 for the treated group vis. the control group (p<0.001.Accordingly, it can be assumed that the Iraqi buffaloes have good potential to produce more milk and fat under standardized feed condition.

  11. Effects of a high-protein/low carbohydrate versus a standard hypocaloric diet on adipocytokine levels and insulin resistance in obese patients along 9 months.

    Science.gov (United States)

    de Luis, Daniel Antonio; Izaola, Olatz; Aller, Rocio; de la Fuente, Beatriz; Bachiller, Rosario; Romero, Enrique

    2015-01-01

    Recent dietary trials and observational studies have focused on the effects of diet on health outcomes such as improvement in levels of surrogate biomarkers. The aim of our study was to examine the changes in weight, adipocytokines levels and insulin resistance after a high-protein/low carbohydrate hypocaloric diet vs. a standard hypocaloric diet during an intervention of 9 months. 331 obese subjects were randomly allocated to one of two diets for a period of 9 months. Diet HP (n=168) (high-protein hypocaloric diet) consisted in a diet of 1050 cal/day, 33% of carbohydrates, 33% of fats and 34% of proteins. Diet S (n=163) (standard protein hypocaloric diet) consisted in a diet of 1093 cal/day, 53% carbohydrates, 27%fats, and 20% proteins. With the diets HP and S, BMI, weight, fat mass, waist circumference, waist-to-hip ratio, systolic blood pressure, total cholesterol, LDL-cholesterol, insulin and HOMA decreased. The decrease at 9 months of (BMI: -2.6±1.3kg/m(2) vs. -2.1±1.2kg/m(2):pdiet HP than Diet S. With both diets, leptin levels decreased. A high-protein/low carbohydrate hypocaloric diet shows a higher weight loss, insulin and HOMA-R decreased after 9 months than a standard hypocaloric diet. The improvement in adipokine levels was similar with both diets. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Expression of Na+/glucose co-transporter 1 (SGLT1) is enhanced by supplementation of the diet of weaning piglets with artificial sweeteners.

    Science.gov (United States)

    Moran, Andrew W; Al-Rammahi, Miran A; Arora, Daleep K; Batchelor, Daniel J; Coulter, Erin A; Daly, Kristian; Ionescu, Catherine; Bravo, David; Shirazi-Beechey, Soraya P

    2010-09-01

    In an intensive livestock production, a shorter suckling period allows more piglets to be born. However, this practice leads to a number of disorders including nutrient malabsorption, resulting in diarrhoea, malnutrition and dehydration. A number of strategies have been proposed to overcome weaning problems. Artificial sweeteners, routinely included in piglets' diet, were thought to enhance feed palatability. However, it is shown in rodent models that when included in the diet, they enhance the expression of Na+/glucose co-transporter (SGLT1) and the capacity of the gut to absorb glucose. Here, we show that supplementation of piglets' feed with a combination of artificial sweeteners saccharin and neohesperidin dihydrochalcone enhances the expression of SGLT1 and intestinal glucose transport function. Artificial sweeteners are known to act on the intestinal sweet taste receptor T1R2/T1R3 and its partner G-protein, gustducin, to activate pathways leading to SGLT1 up-regulation. Here, we demonstrate that T1R2, T1R3 and gustducin are expressed together in the enteroendocrine cells of piglet intestine. Furthermore, gut hormones secreted by the endocrine cells in response to dietary carbohydrates, glucagon-like peptides (GLP)-1, GLP-2 and glucose-dependent insulinotrophic peptide (GIP), are co-expressed with type 1 G-protein-coupled receptors (T1R) and gustducin, indicating that L- and K-enteroendocrine cells express these taste elements. In a fewer endocrine cells, T1R are also co-expressed with serotonin. Lactisole, an inhibitor of human T1R3, had no inhibitory effect on sweetener-induced SGLT1 up-regulation in piglet intestine. A better understanding of the mechanism(s) involved in sweetener up-regulation of SGLT1 will allow the identification of nutritional targets with implications for the prevention of weaning-related malabsorption.

  13. Behavioral characterization of a model of differential susceptibility to obesity induced by standard and personalized cafeteria diet feeding.

    Science.gov (United States)

    Gac, L; Kanaly, V; Ramirez, V; Teske, J A; Pinto, M P; Perez-Leighton, C E

    2015-12-01

    Despite the increase in obesity prevalence over the last decades, humans show large inter-individual variability for susceptibility to diet-induced obesity. Understanding the biological basis of this susceptibility could identify new therapeutic alternatives against obesity. We characterized behavioral changes associated with propensity to obesity induced by cafeteria (CAF) diet consumption in mice. We show that Balb/c mice fed a CAF diet display a large inter-individual variability in susceptibility to diet-induced obesity, such that based on changes in adiposity we can classify mice as obesity prone (OP) or obesity resistant (OR). Both OP and OR were hyperphagic relative to control-fed mice but caloric intake was similar between OP and OR mice. In contrast, OR had a larger increase in locomotor activity following CAF diet compared to OP mice. Obesity resistant and prone mice showed similar intake of sweet snacks, but OR ate more savory snacks than OP mice. Two bottle sucrose preference tests showed that OP decreased their sucrose preference compared to OR mice after CAF diet feeding. Finally, to test the robustness of the OR phenotype in response to further increases in caloric intake, we fed OR mice with a personalized CAF (CAF-P) diet based on individual snack preferences. When fed a CAF-P diet, OR increased their calorie intake compared to OP mice fed the standard CAF diet, but did not reach adiposity levels observed in OP mice. Together, our data show the contribution of hedonic intake, individual snack preference and physical activity to individual susceptibility to obesity in Balb/c mice fed a standard and personalized cafeteria-style diet. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. 7 CFR 51.2542 - U.S. Artificially Opened.

    Science.gov (United States)

    2010-01-01

    ... STANDARDS) United States Standards for Grades of Pistachio Nuts in the Shell § 51.2542 U.S. Artificially Opened. “U.S. Artificially Opened” consists of artificially opened pistachio nuts in the shell which meet...

  15. Artificial sweeteners, caffeine, and alcohol intoxication in bar patrons.

    Science.gov (United States)

    Rossheim, Matthew E; Thombs, Dennis L

    2011-10-01

    Previous laboratory research on alcohol absorption has found that substitution of artificially sweetened alcohol mixers for sucrose-based mixers has a marked effect on the rate of gastric emptying, resulting in elevated blood alcohol concentrations. Studies conducted in natural drinking settings, such as bars, have indicated that caffeine ingestion while drinking is associated with higher levels of intoxication. To our knowledge, research has not examined the effects of alcohol mixers that contain both an artificial sweetener and caffeine, that is, diet cola. Therefore, we assessed the event-specific association between diet cola consumption and alcohol intoxication in bar patrons. We sought to determine whether putative increases in blood alcohol, produced by accelerated gastric emptying following diet cola consumption, as identified in the laboratory, also appear in a natural setting associated with impaired driving. We conducted a secondary analysis of data from 2 nighttime field studies that collected anonymous information from 413 randomly selected bar patrons in 2008 and 2010. Data sets were merged and recoded to distinguish between energy drink, regular cola, diet cola, and noncaffeinated alcohol mixers. Caffeinated alcohol mixers were consumed by 33.9% of the patrons. Cola-caffeinated mixed drinks were much more popular than those mixed with energy drinks. A large majority of regular cola-caffeinated mixed drink consumers were men (75%), whereas diet cola-caffeinated mixed drink consumers were more likely to be women (57%). After adjusting for the number of drinks consumed and other potential confounders, number of diet cola mixed drinks had a significant association with patron intoxication (β = 0.233, p 0.05). Caffeine's effect on intoxication may be most pronounced when mixers are artificially sweetened, that is, lack sucrose which slows the rate of gastric emptying of alcohol. Risks associated with on-premise drinking may be reduced by greater

  16. Chemical analysis of coal by energy dispersive x-ray fluorescence utilizing artificial standards

    International Nuclear Information System (INIS)

    Wheeler, B.D.

    1982-01-01

    Accurate determinations of the elemental composition of coal by classical methods can be quite difficult and are normally very time consuming. X-ray fluorescence utilizing the powder method, however, has the ability of providing accurate and rapid analyses. Unfortunately, well characterized standards, although available, are not plentiful. In addition, the durability of stability of ground and pelletized coal samples is poor resulting in deterioration with time. As a result, artificial coal standards were prepared from certified geological materials by fusing in lithium tetraborate in percentages approximating expected ash contents and compositions in coal. Since the lithium tetraborate comprises about the same percentage of the standard as does the carbon, hydrogen, and oxygen in coal, the ground and pelletized coal sample can be assayed against the fused calibration curves by compensating for the differences in the mass absorption coefficients of the two matrices. 5 figures, 4 tables

  17. A practical, efficient and low cost diet for rearing the Mediterranean fruit fly larvae

    International Nuclear Information System (INIS)

    Manoukas, A.G.; Zografou, E.N.

    2000-01-01

    The Mediterranean fruit fly Ceratitis capitata Wied. (Diptera: Tephritidae), has been artificially reared and used for the application of the sterile insect technique and other purposes, throughout the world. The larval diet used is rather expensive and it is mixed in the rearing facility. The most expensive ingredient used in this diet is yeast which is variable in composition and has a relatively short shelf life due mainly to its high nutritional value. This is particularly true for all countries like Greece which do not manufacture brewer's yeast. Also, it is widely known that the Mediterranean fruit fly larvae grow in a wide variety of fruits and artificial diets. These fruits and artificial diets, although very different in chemical/nutritional as well as physical/ecological parameters, are successfully tolerated and utilised by the larvae. These observations prompted the initiation of research into diets containing a variety of low cost ingredients widely used in the vertebrate feed industry and easily found in any country. To our knowledge, no one has tested complete diets produced by well-established feed manufacturers for larval rearing of this insect

  18. Efeitos de extratos de plantas na biologia de Spodoptera frugiperda (J. E. Smith, 1797 (Lepidoptera: Noctuidae mantida em dieta artificial Effects of plant extracts on the biology of Spodoptera frugiperda (J. E. Smith, 1797 (Lepidoptera: Noctuidae maintained under artificial diet

    Directory of Open Access Journals (Sweden)

    Gilberto Pedreira Santiago

    2008-06-01

    Full Text Available Avaliaram-se os efeitos dos extratos aquosos a 10% de folhas e ramos de arruda (Ruta graveolens L., folhas e ramos de melão-de-são-caetano (Momordica charantia L., folhas do alecrim-pimenta (Lippia sidoides Cham. e fruto verde de mamona (Ricinus communis L., sobre a biologia da lagarta-do-cartucho do milho (Spodoptera frugiperda, mantida em dieta artificial. Os parâmetros avaliados foram duração e viabilidade das fases larval e pupal, peso de pupa, fecundidade, fertilidade e longevidade de adultos. Larvas de S. frugiperda recém-eclodidas foram colocadas em tubos de ensaio com dieta artificial, contendo os extratos de cada material testado. O extrato aquoso do fruto verde de R. communis apresentou bioatividade, nos parâmetros duração larval e pupal e peso de pupa. O extrato aquoso de R. graveolens reduziu o peso de pupa. A dieta contendo extrato de folhas e ramos de M. charantia reduziu a viabilidade larval e o peso de pupa. O extrato aquoso de folhas de L. sidoides não afetou as fases larval e pupal, reduziu a postura e a viabilidade de ovos e aumentou a longevidade de adultos de S. frugiperda. A viabilidade de pupa não foi afetada pelos extratos testados.The effects of aqueous extracts, at 10% concentration of leaves and branches of Ruta graveolens L., leaves and branches of Momordica charantia L., leaves of Lippia sidoides Cham. and green fruits of Ricinus communis L. were evaluated on the biology of fall armyworm (Spodoptera frugiperda maintained under artificial diet. The evaluated parameters were: duration and viability of the larval and pupal phases, pupa weight, fecundity, fertility and longevity of adults. Just-hatched larvae of S. frugiperda was placed in test tube with artificial diet containing extracts of each tested material. The aqueous extract of the green fruits of R. communis presented bioactivity upon duration and weight of larval and pupal phases. The aqueous extract of R. graveolens reduced weight of pupa. The diet

  19. Mass production in liquid diet and radiosterilization of South American fruit fly Anastrepha sp.1 aff. fraterculus (Wied., 1830) (Diptera: Tephritidae)

    International Nuclear Information System (INIS)

    Kamiya, Aline Cristiane

    2010-01-01

    Both the biological control techniques as the Sterile Insect Technique (SIT), are used in many countries to control, suppress and even eradicate fruit flies and other pests in agriculture and public health. The use of such techniques minimizes the continuous employment of insecticides, protects the environment and conforms to standards for food safety. However, it is necessary to implement such programs, technology to produce millions of parasitoids and the pest in its own laboratory with biological quality similar to the insects found in nature and cost competitive with chemical control. The objectives of this study was to establish protocols for artificial rearing of A. sp. 1 aff. fraterculus in liquid larval diet that will achieve levels of mass production for a possible reduction in the cost of establishing and determining the dose of radiation sterilization of adult A. sp. 1 aff. fraterculus meeting the quality parameters required by the Sterile Insect Technique with insects from the creation of Radioentomology Laboratory of CENA/USP. Seven experimental diets compared to the conventional diet used in Radioentomology Lab. of CENA/USP, which was used as control. All seven diets have in common the exclusion of agar in its formulation. Only two of the diets tested were suitable for larval development of the fly, they compared with the standard diet, showed inferior results with respect to the volume of recovered larvae, pupae and weight of emergency, however, no significant differences regarding the periods of development , pupal recovery, sex ratio and longevity under stress. It is possible to replace the diet with agar for liquid diets for artificial creation of A. sp. 1 aff. fraterculus, reduced cost and greater convenience of handling, but due to their quality standards lower than the standard diet, more tests are needed especially regarding the adaptability of the insect to the new environment. To determine the sterilizing dose this study examined the

  20. Effect of a High-Protein Diet versus Standard-Protein Diet on Weight Loss and Biomarkers of Metabolic Syndrome: A Randomized Clinical Trial.

    Science.gov (United States)

    Campos-Nonato, Ismael; Hernandez, Lucia; Barquera, Simon

    2017-01-01

    Some studies have shown that protein-enriched diets can lead to greater weight loss and improvements in biomarkers of metabolic syndrome (MeS) than standard protein diets. Therefore, the aim of this study was to determine the effect of increased protein intake on weight loss in Mexican adults with MeS. Randomized controlled trial in 118 adults aged 47.4 ± 11.5 years and meeting the established criteria for MeS were randomized to prescribed hypocaloric diets (500 kcal less than resting metabolic rate) providing either 0.8 g/kg body weight (standard protein diet (SPD)) or 1.34 g/kg body weight (higher protein diet (HPD)) for 6 months. Body weight, waist circumference, percent body fat by bioimpedance analysis, fasting blood glucose, fasting insulin, hemoglobin A1c, total cholesterol, high-density lipoprotein (HDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, triglycerides, C-reactive protein, creatinine, blood urea nitrogen, alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transferase were measured at baseline, 3 months and at 6 months. There were 105 subjects (51 for SPD and 54 for HPD) who completed the trial. Overall weight loss was 5.1 ± 3.6 kg in the SPD group compared to 7.0 ± 3.7 kg in the in HPD group. Both groups lost a significant percent of centimeters of waist circumference (SPD -6.5 ± 2.6 cm and HPD -8.8 ± 2.6 cm). There was no statistical difference Except for the varying weight losses the two groups did not show any further differences overall. However in the subgroup judged to be adherent more than 75% of the time with the prescribed diets, there was a significant difference in mean weight loss (SPD -5.8% vs. HPD -9.5%) after adjusting for baseline BMI. Both groups demonstrated significant decreases in waist circumference, glucose, insulin, triglycerides, and VLDL cholesterol, but there were no differences between the groups. There were no changes in blood tests for liver or renal function. There were no

  1. Effect of a High-Protein Diet versus Standard-Protein Diet on Weight Loss and Biomarkers of Metabolic Syndrome: A Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    Ismael Campos-Nonato

    2017-06-01

    Full Text Available Background: Some studies have shown that protein-enriched diets can lead to greater weight loss and improvements in biomarkers of metabolic syndrome (MeS than standard protein diets. Therefore, the aim of this study was to determine the effect of increased protein intake on weight loss in Mexican adults with MeS. Methods: Randomized controlled trial in 118 adults aged 47.4 ± 11.5 years and meeting the established criteria for MeS were randomized to prescribed hypocaloric diets (500 kcal less than resting metabolic rate providing either 0.8 g/kg body weight (standard protein diet (SPD or 1.34 g/kg body weight (higher protein diet (HPD for 6 months. Body weight, waist circumference, percent body fat by bioimpedance analysis, fasting blood glucose, fasting insulin, hemoglobin A1c, total cholesterol, high-density lipoprotein (HDL cholesterol, very-low-density lipoprotein (VLDL cholesterol, triglycerides, C-reactive protein, creatinine, blood urea nitrogen, alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transferase were measured at baseline, 3 months and at 6 months. Results: There were 105 subjects (51 for SPD and 54 for HPD who completed the trial. Overall weight loss was 5.1 ± 3.6 kg in the SPD group compared to 7.0 ± 3.7 kg in the in HPD group. Both groups lost a significant percent of centimeters of waist circumference (SPD -6.5 ± 2.6 cm and HPD -8.8 ± 2.6 cm. There was no statistical difference Except for the varying weight losses the two groups did not show any further differences overall. However in the subgroup judged to be adherent more than 75% of the time with the prescribed diets, there was a significant difference in mean weight loss (SPD -5.8% vs. HPD -9.5% after adjusting for baseline BMI. Both groups demonstrated significant decreases in waist circumference, glucose, insulin, triglycerides, and VLDL cholesterol, but there were no differences between the groups. There were no changes in blood tests for

  2. Cadmium bioavailability to Hyalella azteca from a periphyton diet compared to an artificial diet and application of a biokinetic model

    Energy Technology Data Exchange (ETDEWEB)

    Golding, Lisa A., E-mail: lisa.golding@csiro.au [Department of Biology, University of Waterloo, Waterloo, Ontario N2L 3G1 (Canada); Borgmann, Uwe [Environment Canada, 867 Lakeshore Road, Burlington, Ontario L7R 4A6 (Canada); George Dixon, D. [Department of Biology, University of Waterloo, Waterloo, Ontario N2L 3G1 (Canada)

    2013-01-15

    Differences between the bioavailability of cadmium in a periphyton diet and an artificial laboratory diet (TetraMin{sup Registered-Sign }) have important consequences for predicting bioaccumulation and toxicity in the freshwater amphipod Hyalella azteca. The assimilation efficiency (AE) of Cd was compared between periphyton and TetraMin{sup Registered-Sign} at low (1510 and 358 nmol/g ash-free dry mass respectively) and chronically lethal (31,200 and 2890 nmol/g ash-free dry mass respectively) Cd concentrations and in fresh and dry forms using a {sup 109}Cd radiotracer pulse-chase feeding technique. Assimilation efficiency of Cd from periphyton (AE = 3-14%) was lower than that for TetraMin{sup Registered-Sign} (AE = 44-86%) regardless of Cd concentration or food form. Ingestion rate (IR) was lower for dry than fresh forms of periphyton (0.042 and 0.16 g AFDM/g H. azteca/day respectively) and TetraMin{sup Registered-Sign} (0.19 and 0.87 AFDM/g H. azteca/day respectively) and depuration rate (k{sub e}) did not differ statistically with food type, form or Cd concentration (0.032-0.094 d{sup -1}). Biokinetic models with parameters of AE, IR and k{sub e} were used to estimate bioaccumulation from the separate food types. These estimates were compared to those from an independent chronic Cd saturation bioaccumulation model. While the model estimates did not concur, a sensitivity analysis indicated that AE and IR were the most influential biokinetic model parameters for Cd in periphyton and TetraMin{sup Registered-Sign} respectively. It was hypothesized that AE was underestimated for Cd in periphyton due to a non-adapted gut enzyme system and IR was overestimated for Cd in TetraMin{sup Registered-Sign} due to an initial rapid ingestion phase in H. azteca's feeding habits. This research demonstrated the importance of using ecologically relevant food types in laboratory experiments and verifying acute biokinetic model predictions of dietary metal contribution with

  3. In rats fed high-energy diets, taste, rather than fat content, is the key factor increasing food intake: a comparison of a cafeteria and a lipid-supplemented standard diet

    Directory of Open Access Journals (Sweden)

    Laia Oliva

    2017-09-01

    Full Text Available Background Food selection and ingestion both in humans and rodents, often is a critical factor in determining excess energy intake and its related disorders. Methods Two different concepts of high-fat diets were tested for their obesogenic effects in rats; in both cases, lipids constituted about 40% of their energy intake. The main difference with controls fed standard lab chow, was, precisely, the lipid content. Cafeteria diets (K were self-selected diets devised to be desirable to the rats, mainly because of its diverse mix of tastes, particularly salty and sweet. This diet was compared with another, more classical high-fat (HF diet, devised not to be as tasty as K, and prepared by supplementing standard chow pellets with fat. We also analysed the influence of sex on the effects of the diets. Results K rats grew faster because of a high lipid, sugar and protein intake, especially the males, while females showed lower weight but higher proportion of body lipid. In contrast, the weight of HF groups were not different from controls. Individual nutrient’s intake were analysed, and we found that K rats ingested large amounts of both disaccharides and salt, with scant differences of other nutrients’ proportion between the three groups. The results suggest that the key differential factor of the diet eliciting excess energy intake was the massive presence of sweet and salty tasting food. Conclusions The significant presence of sugar and salt appears as a powerful inducer of excess food intake, more effective than a simple (albeit large increase in the diet’s lipid content. These effects appeared already after a relatively short treatment. The differential effects of sex agree with their different hedonic and obesogenic response to diet.

  4. Effect of diet on male reproductive tract of Podisus nigrispinus (Dallas (Heteroptera: Pentatomidae

    Directory of Open Access Journals (Sweden)

    W. P Lemos

    Full Text Available The morphology and histology of the reproductive tract of males of the predator Podisus nigrispinus (Dallas fed on different diets were studied. P. nigrispinus was fed on diets of: larvae of Alabama argillacea (Hübner, Tenebrio molitor L., Musca domestica L., and an artificial diet. The male reproductive tract, independent of diet, showed testes with intense red coloration in a compact, circular, or slightly oval structure. The vasa deferentia were similar in color to the testes and formed long filaments, which joined with the yellow-cream colored ejaculatory duct. The morphological characteristics of the male reproductive tract were similar under all diets, except for the artificial one. The histological studies demonstrated that independent of the diet the testes of P. nigrispinus were composed of four to six follicles. The testes with six follicles generally had four developed and two atrophied follicles. The morphological and histological differences of the testes of P. nigrispinus when fed with different prey are presented and discussed.

  5. Oxidative costs of reproduction: Oxidative stress in mice fed standard and low antioxidant diets.

    Science.gov (United States)

    Vaanholt, L M; Milne, A; Zheng, Y; Hambly, C; Mitchell, S E; Valencak, T G; Allison, D B; Speakman, J R

    2016-02-01

    Lactation is one of the most energetically expensive behaviours, and trade-offs may exist between the energy devoted to it and somatic maintenance, including protection against oxidative damage. However, conflicting data exist for the effects of reproduction on oxidative stress. In the wild, a positive relationship is often observed, but in laboratory studies oxidative damage is often lower in lactating than in non-breeding animals. We hypothesised that this discrepancy may exist because during lactation food intake increases many-fold resulting in a large increase in the intake of dietary antioxidants which are typically high in laboratory rodent chow where they are added as a preservative. We supplied lactating and non-breeding control mice with either a standard or low antioxidant diet and studied how this affected the activity of endogenous antioxidants (catalase, superoxide dismutase; SOD, and glutathione peroxidise; GPx) and oxidative damage to proteins (protein carbonyls, PC) in liver and brain tissue. The low antioxidant diet did not significantly affect activities of antioxidant enzymes in brain or liver, and generally did not result in increased protein damage, except in livers of control mice on low antioxidant diet. Catalase activity, but not GPx or SOD, was decreased in both control and lactating mice on the low antioxidant diet. Lactating mice had significantly reduced oxidative damage to both liver and brain compared to control mice, independent of the diet they were given. In conclusion, antioxidant content of the diet did not affect oxidative stress in control or reproductive mice, and cannot explain the previously observed reduction in oxidative stress in lactating mammals studied in the laboratory. The reduced oxidative stress in the livers of lactating mice even under low antioxidant diet treatment was consistent with the 'shielding' hypothesis. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Evaluation of the Mating Competitiveness of the Adult Oriental Fruit Fly Reared as Larvae in Liquid vs. Those Raised on Standard Wheat-based Diets

    Science.gov (United States)

    Three strains (standard lab, DTWP pupal color sexing strain and wild strain) of adult oriental fruit flies, which were reared as larvae on a liquid diet, mill feed diet (Tanaka’s diet), or natural host fruit diet, were evaluated for mating competitiveness in both indoor and outdoor Boller’s mating c...

  7. A review of maturation diets for mud crab genus Scylla broodstock: Present research, problems and future perspective.

    Science.gov (United States)

    Azra, Mohamad N; Ikhwanuddin, Mhd

    2016-03-01

    Study of broodstock maturation diets is important in order to increase the quality of berried females, which indirectly improve the larval quantity in the hatchery production of cultured species. This paper reviewed the studies on the maturation diets for mud crab broodstock, genus Scylla and compared independently to identify their effect on reproductive performance and larval quality. The broodstock is usually caught from the wild and held in the spawning or maturation tank for further use of hatchery seed production. Mud crab broodstock was fed either natural diet, artificial diet or mixed diet. Trash fishes were commonly used as a natural feed for mud crab broodstock; meanwhile artificial diets are from formulated fish meal and various kinds of feed. The results indicated that mud crab broodstock has a high dietary requirement for lipids, fatty acids and protein which are to be used during the maturation and breeding processes. However, the natural diet produce better larval quality compared to the artificial diet. The mixed diet is the better diet which resulted in better reproductive performances such as growth, survival, fecundity and maturation processes. This review also discusses the problems in the previous studies for the potential future research to develop very high quality and cost-effective formulated diet for the enhancement of broodstock and seed production technology. Information from this review can be useful in developing a better quality of crustacean broodstock's diet for commercial hatchery production.

  8. Evaluation of palatability, protein and energi consumtion of adult lizard (Mabouya multifasciata by feed them of with many diet variations

    Directory of Open Access Journals (Sweden)

    RONI RIDWAN

    2001-01-01

    Full Text Available Lizard (Mabouya multifasciata, one of natural resources that spreads almost all Indonesian islands. The animals can potentially be used as a source of protein and medicine as well as a pet. The objectives of the research were therefore to investigate the preference of certain kind of diet, measure the protein and energy consumption, and also to observe the weight gain of the lizard. Seventy two lizards consisting of 36 females that each having weight of 29.7 + 2.6 grams and 36 male that having weight of 30.0 + 2.9 grams were used in this study. These lizards were captured from their wild nature around Bogor, Ciamis, Sumedang and Cianjur of West Java. Block experimental design was used, with 4 diet treatments and two grouping based on sex, (male and female. The diets were crickets, mealworm, red ant larva and artificial diet. Each tree lizards was put on 0.30m x 0.30m x 0.50m nets made from glass. Diets were given 3% dry matter of lizard body weight and water has given ad libitum. Parameter measured was dry matter consumption, protein consumption, energy consumption and body weight gain. ANOVA used for the data analysis, followed with Duncan range-test. The result showed that dry matter consumption of crickets, red ant larva and artificial diet was significantly (P<0.01 higher than mealworms. Consumption of crickets crude-protein was significantly (P<0.01 higher than mealworms, red ant larva and artificial diet. Mealworm crude-protein consumption was significantly (P<0.01 lower compared with both red ant larva and artificial diet. Crickets and red ant larva showed higher affect (P<0.01 on body weight gain than artificial diet. However, there were no significant effect of all diet on consumption, brute energy and relatively metabolic energy. Grouping based on sex also did not show any significant affect to all parameters observed. It can be concluded that lizards prefer eating crickets, red ant larva and diet than mealworms.

  9. [Development of a multimedia learning DM diet education program using standardized patients and analysis of its effects on clinical competency and learning satisfaction for nursing students].

    Science.gov (United States)

    Hyun, Kyung Sun; Kang, Hyun Sook; Kim, Won Ock; Park, Sunhee; Lee, Jia; Sok, Sohyune

    2009-04-01

    The purpose of this study was to develop a multimedia learning program for patients with diabetes mellitus (DM) diet education using standardized patients and to examine the effects of the program on educational skills, communication skills, DM diet knowledge and learning satisfaction. The study employed a randomized control posttest non-synchronized design. The participants were 108 third year nursing students (52 experimental group, 56 control group) at K university in Seoul, Korea. The experimental group had regular lectures and the multimedia learning program for DM diet education using standardized patients while the control group had regular lectures only. The DM educational skills were measured by trained research assistants. The students who received the multimedia learning program scored higher for DM diet educational skills, communication skills and DM diet knowledge compared to the control group. Learning satisfaction of the experimental group was higher than the control group, but statistically insignificant. Clinical competency was improved for students receiving the multimedia learning program for DM diet education using standardized patients, but there was no statistically significant effect on learning satisfaction. In the nursing education system there is a need to develop and apply more multimedia materials for education and to use standardized patients effectively.

  10. Dahl salt-sensitive rats develop hypovitaminosis D and hyperparathyroidism when fed a standard diet

    Science.gov (United States)

    Thierry-Palmer, Myrtle; Cephas, Stacy; Sayavongsa, Phouyong; Doherty, Akins; Arnaud, Sara B.

    2005-01-01

    The Dahl salt-sensitive rat (S), a model for salt-sensitive hypertension, excretes protein-bound 25-hydroxyvitamin D (25-OHD) into urine when fed a low salt diet. Urinary 25-OHD increases during high salt intake. We tested the hypothesis that continuous loss of 25-OHD into urine would result in low plasma 25-OHD concentration in mature S rats raised on a standard diet. Dahl S and salt-resistant (R) male rats were raised to maturity (12-month-old) on a commercial rat diet (1% salt) and switched to 0.3% (low) or 2% (high) salt diets 3 weeks before euthanasia. Urine (24 h) was collected at the end of the dietary treatments. Urinary 25-OHD and urinary 25-OHD binding activity of S rats were three times that of R rats, resulting in lower plasma 25-OHD and 24,25-dihydroxyvitamin D concentrations in S rats than in R rats (P D concentrations than those fed 0.3% salt (P = 0.002). S rats excreted more calcium into urine than R rats (P D and high plasma 1,25-dihydroxyvitamin D and PTH concentrations seen in the mature S rats have also been reported for elderly patients with low-renin (salt-induced) hypertension. An implication of this study is that low vitamin D status may occur with age in salt-sensitive individuals, even when salt intake is normal.

  11. Large scale artificial rearing of Anastrepha sp.1 aff. fraterculus (Diptera: Tephritidae in Brazil

    Directory of Open Access Journals (Sweden)

    Julio Marcos Melges Walder

    2014-08-01

    Full Text Available Some species of the genus Anastrepha (Diptera: Tephritidae are successfully managed by matching the sterile insect technique with parasitoid releases. Such strategies used in integrated pest management can be implemented only where insect mass-rearing programs are feasible. In this study, we show the process of domestication, rearing technology and quality control data obtained from 54 generations of Anastrepha sp.1 aff. fraterculus (Wiedemann, 1830 kept under fully artificial conditions. Eggs were collected by an artificial oviposition panel consisting of one side of the cage made of blue voile fabric externally covered with a thin layer of silicon rubber. They were then air-bubbled in water at 25 ºC for 48 h before seeding. Larvae were reared on the regular laboratory artificial diet with 66 % of agar reduction turning over a semi-liquid diet, which reduced costs and improved insect quality. The adult and larval diets were composed of local ingredients including hydrolyzed yeast. When large-scale production of this fly is contemplated, the critical stage is larval development. This system of artificial rearing for A. fraterculus sp.1 developed in Brazil, allows for the production of a large number of insects of excellent quality using local ingredients and less agar in diet composition than the original medium used for this species. By reducing the interval of egg collection, the system might be optimized in terms of insect yield and, therefore, meet the demands of A. fraterculus sp.1 with regard to integrated pest management purposes.

  12. Feasibility and efficacy of an isocaloric high-protein vs. standard diet on insulin requirement, body weight and metabolic parameters in patients with type 2 diabetes on insulin therapy

    DEFF Research Database (Denmark)

    Luger, M; Holstein, B; Schindler, K

    2013-01-01

    To determine the feasibility and efficacy of a high-protein diet compared with a standard diet aiming for weight maintenance in insulin treated type-2 diabetic patients on insulin requirement, body weight and metabolic parameters over 12 weeks.......To determine the feasibility and efficacy of a high-protein diet compared with a standard diet aiming for weight maintenance in insulin treated type-2 diabetic patients on insulin requirement, body weight and metabolic parameters over 12 weeks....

  13. Response of broiler chickens to diets containing artificially dried ...

    African Journals Online (AJOL)

    The effect of feeding high-moisture maize grains dried in the sun or artificially in a forced draught oven at 80, 90 or 100 °C for 24 hours and supplemented with microbial enzymes (Avizyme 1502 and Phyzyme XP) on growth performance, visceral organs, tissue protein, enzyme activity and gut development was investigated ...

  14. Apparent or Standardized Ileal Digestibility of Amino Acids of Diets Containing Different Protein Feedstuffs Fed at Two Crude Protein Levels for Growing Pigs

    Directory of Open Access Journals (Sweden)

    A. O. Adebiyi

    2015-09-01

    Full Text Available The current study determined the apparent or standardized ileal digestibility of amino acids (AID or SID of AA in growing pigs fed diets containing three protein feedstuffs with different fiber characteristics at two dietary crude protein (CP levels. Twenty boars (Yorkshire×Landrace with average initial body weight of 35 (±2.6 kg were fitted with a simple T-cannula at the distal ileum. These pigs were offered six diets containing soybean meal (SBM, canola meal (CM or corn distillers dried grains with solubles (corn-DDGS that were either adequate (19% or marginal (15% in CP using a triplicated 6×2 Youden Square Design. Except for Met, Trp, Cys, and Pro, AID of AA was greater (p<0.05 in the SBM diet compared with the CM diet. Apparent ileal digestibility for Gly and Asp was greater (p<0.05 in the SBM diet compared with the corn-DDGS diet. The AID of Ile, Leu, Phe, Val, Ala, Tyr, and Asp was greater (p<0.05 in the corn-DDGS diet compared with the CM diet. Standardized ileal digestibility of AA was greater (p<0.05 in the SBM diet compared with the CM diet for all AA except Trp and Pro. The SID of Ile, Leu, Val, Ala, Tyr, and Asp was greater (p<0.05 in the corn-DDGS diet compared with the CM diet. It was concluded that protein feedstuff affects ileal AA digestibility and is closely related to dietary fiber characteristics, and a 4-percentage unit reduction in dietary CP had no effect on ileal AA digestibility in growing pigs.

  15. A novel bioassay to evaluate the potential of Beauveria bassiana strain NI8 and the insect growth regulator novaluron against Lygus lineolaris on a non-autoclaved solid artificial diet

    Science.gov (United States)

    Portilla, Maribel; Snodgrass, Gordon; Luttrell, Randall; Jaronski, Stefan

    2014-01-01

    Abstract A non-autoclaved solid diet was used to evaluate the entomopathogenic fungus Beauveria bassiana (Balsamo) Vuillemin (Hypocreales: Clavicipitaceae) strain NI8 and the insect growth regulator novaluron (Diamond® 0.83EC insecticide) for control of the tarnished plant bug, Lygus lineolaris (Palisot de Beauvois) (Hemiptera: Miridae). The diet was composed of toasted wheat germ, ground lima bean meal, soy flour, yolk of chicken eggs, inhibitor, and agar. It was prepared in one step by blending the ingredients in boiling water. The diet was used to bioassay L. lineolaris from the second instar to the adult stage. Fourth and fifth instars and adults of L. lineolaris were more susceptible than second and third instars to infection by B. bassiana , whereas second, third, and fourth instars had higher mortality than fifth instars 10 days after exposure to novaluron. No effects on longevity were observed in adults treated with novaluron when compared with the control, but longevity was significantly different from that of adults exposed to B. bassiana . Adults of L. lineolaris were maintained for over a month without changing the diet. The non-autoclaved diet is semi-liquid before it cools, which facilitates the mechanics of diet packaging similar to food packaging or lepidopteran diet preparation. This solid artificial diet for Lygus bugs provides improved research capacity for studying the ecology and susceptibility of Lygus spp. to a number of different control agents, including beneficial organisms, insect pathogens, and insecticidal toxins being developed for transgenic technologies. PMID:25368059

  16. BIOCLAIMS standard diet (BIOsd): a reference diet for nutritional physiology

    Czech Academy of Sciences Publication Activity Database

    Hoevenaars, F.P.M.; van Schothorst, E. M.; Horáková, Olga; Voigt, A.; Rossmeisl, Martin; Pico, C.; Caimari, A.; Kopecký, Jan; Klaus, S.; Keijer, J.

    2012-01-01

    Roč. 7, č. 3 (2012), s. 399-404 ISSN 1555-8932 R&D Projects: GA MŠk(CZ) 7E10059; GA MŠk(CZ) OC08008 Institutional research plan: CEZ:AV0Z50110509 Institutional support: RVO:67985823 Keywords : semi-purified diet * nutrient requirements * rat * mouse Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition Impact factor: 3.329, year: 2012

  17. Obtenção de uma dieta artificial para Bradysia hygida (Diptera, Sciaridae

    Directory of Open Access Journals (Sweden)

    Angelo de Lima Francisco

    1984-01-01

    Full Text Available Some artificial diets were tested and their efficiency assessed from percentage of pupation and emergence, time to emergence, pupal weight, ovary development and maintenance of generation. The best results were obtained with a yeast and starch basal diet. The other products tested were: wheat germ, soybean, fish flour, blood flour and meat flour.

  18. Soya bean meal increases litter moisture and foot pad dermatitis in maize and wheat based diets for turkeys but maize and non-soya diets lower body weight.

    Science.gov (United States)

    Hocking, P M; Vinco, L J; Veldkamp, T

    2018-04-01

    1. A 2 × 2 factorial experiment was conducted to compare the effects of wheat or maize based diets differing in dietary electrolyte balance (DEB) on litter moisture and foot pad dermatitis (FPD) at 4, 8 and 12 weeks of age in heavy-medium turkeys. A second objective was to investigate the effects on foot pad dermatitis of the interaction between dietary composition and artificially increasing litter moisture by adding water to the litter. 2. High DEB diets contained soya as the main protein source whereas low DEB diets did not contain soya bean meal. Diets were formulated to be iso-caloric and iso-nitrogenous in each of 3 successive 4-week phases following recommended dietary compositions. DEB concentrations were 330, 290 and 250 mEq/kg in high DEB diets and 230, 200 and 180 mEq/kg in low DEB diets. 3. Litter moisture and mean FPD score were higher in turkeys fed on high DEB diets compared with low DEB diets whereas there was no difference between maize and wheat. 4. Food intake was similar and body weight was lower after litter moisture was artificially raised in the wet compared with the dry litter treatment and there was no interaction with dietary composition. 5. Mean body weight and feed intake were higher in turkeys fed on wheat compared with maize and in high DEB compared with low DEB diets at 12 weeks of age. 6. Lowering dietary DEB for turkeys may improve litter moisture and lower the prevalence of FPD in commercial turkey flocks.

  19. Demographic parameters of Nezara viridula (L.) (Heteroptera: Pentatomidae) reared on two diets developed for Lygus spp

    Science.gov (United States)

    Two artificial diets developed for rearing Lygus spp., a fresh yolk chicken egg based-diet (FYD) and a dry yolk chicken egg based-diet (DYD), were evaluated as an alternative food source for rearing the southern green stink bug, Nezara viridula (L.) (Heteroptera: Pentatomidae). Survival to adult was...

  20. Effect of -55CT Polymorphism of UCP3 on Insulin Resistance and Cardiovascular Risk Factors after a High Protein/Low Carbohydrate versus a Standard Hypocaloric Diet.

    Science.gov (United States)

    de Luis, Daniel Antonio; Aller, Rocío; Izaola, Olatz; Romero, Enrique

    2016-01-01

    The C/C genotype of a polymorphism in the uncoupling protein3 (UCP3) promoter (-55C->T) (rs1800849) is associated with an increased body mass index. The aim of our study was to investigate the effect of polymorphism on the UCP3 promoter (-55C->T) on insulin resistance and cardiovascular risk factors secondary to a high protein/low carbohydrate vs. a standard hypocaloric diets (1,000 kcal/day). A population of 283 obese subjects was analyzed in a randomized trial. A nutritional evaluation was performed at the beginning and at the end of a 9-month period in which subjects received 1 of 2 diets (diet HP: high protein/low carbohydrate vs. diet S: standard diet). Weight improvement was higher in non-T carriers. With both diets and only in wild genotype (diet HP vs. diet S), total cholesterol (-9.7 ± 4.0 vs. -11.1 ± 2.0 mg/dl; p > 0.05) and low density lipoprotein (LDL) cholesterol (-8.3 ± 3.0 vs. -5.5 ± 2.7 mg/dl; p > 0.05) decreased. The improvement in these parameters was similar in subjects with diet HP than HS. With diet HP and only in wild genotype, glucose (-5.2 ± 2.2 mg/dl; p diet showed a better metabolic response than S diet in 55CC homozygous. © 2016 S. Karger AG, Basel.

  1. Response of broiler chickens to diets containing artificially dried ...

    African Journals Online (AJOL)

    mbhuiya3

    Department of Animal Science, School of Environmental and Rural Science, University .... reduction in in vitro digestibility, showed that the quality of diets with stack ... some enzyme preparations are also used to increase the nutritional value of ...... Life Sci. 57, 1793-1801. Gabriel, I., Lessire, M., Mallet, S. & Guillot, J.F., 2006.

  2. Application of artificial neural network in radiographic diagnosis

    International Nuclear Information System (INIS)

    Piraino, D.; Amartur, S.; Richmond, B.; Schils, J.; Belhobek, G.

    1990-01-01

    This paper reports on an artificial neural network trained to rate the likelihood of different bone neoplasms when given a standard description of a radiograph. A three-layer back propagation algorithm was trained with descriptions of examples of bone neoplasms obtained from standard radiographic textbooks. Fifteen bone neoplasms obtained from clinical material were used as unknowns to test the trained artificial neural network. The artificial neural network correctly rated the pathologic diagnosis as the most likely diagnosis in 10 of the 15 unknown cases

  3. Artificial humidification for the mechanically ventilated patient.

    Science.gov (United States)

    Selvaraj, N

    Caring for patients who are mechanically ventilated poses many challenges for critical care nurses. It is important to humidify the patient's airways artificially to prevent complications such as ventilator-associated pneumonia. There is no gold standard to determine which type of humidification is best for patients who are artificially ventilated. This article provides an overview of commonly used artificial humidification for mechanically ventilated patients and discusses nurses' responsibilities in caring for patients receiving artificial humidification.

  4. The Use Of Local Product Yeast For Substitution Torula Yeast In The Formulation Of Artificial Diet Fruit Fly Larvae Bactrocera Carambolae Drew and Hancock

    International Nuclear Information System (INIS)

    Sikumbang, I.; Nasution, A.I.; Indarwatmi, M.; Kuswandi, A.N.

    2000-01-01

    The use of local product yeast I.e brewer yeast, yeast of tapai (fermented cassava), yeast of tempe (fermented soy beam), and brem(intoxicating beverage made of fermented rice) after cooked and uncooked were used to substitute torula yeast to reduce cost production for mass-rearing of fruit fly had been carried out. Artificial diet formulation consisted of torula yeast, wheat bran, nipagin, sodium benzoate, cane sugar, water and HCI ti make pH of 4. One kilogram of diet was inoculated with 1 ml of fruit fly eggs. Parameters of the experiment were, the number of pupae, weight of pupae, percentage of pupae and the percentage of viable fly. The results showed that the number of pupae were 6356 for brewers yeast with cooked and 0.942 gram/100 pupae for brem. Percentage viable emergence fly were 70%, 18.25% and 15.25% for brewers yeast with cooked and uncooked respectively. Cost production for 1.000.000 using cooked brewer yeast was reduced about Rp.179,200 or cost efficiency were 55.56%

  5. Histochemical responses of rats exercised in two weekly frequencies and ingesting standard or hypercaloric diet

    Directory of Open Access Journals (Sweden)

    FI Freitas

    2009-07-01

    Full Text Available This study investigated if overfed rats present morphological and histochemical muscle adaptation similar to normally fed, both submitted to two different weekly frequencies of training. Thirty male Wistar rats were fed either with standard chow (SCØ or with hypercaloric diet (HCØ. They were subdivided into six subgroups: sedentary (SCØ and HCØ, trained twice/week (SC2 and HC2 and trained five times/week (SC5 and HC5. The trained groups swam 60 min/day, during 10 weeks. Twenty four hours after the last training, samples of Gastrocnemius were excised and stained with HE, NADH-TR and m-ATPase, and the capillary density was calculated. Total heart mass (HM and the mass of atrium (AM, left (LV and right (RV ventricles were excised and weighted. The comparisons were made by ANOVA and by Covariance analysis, adjusting the variables by body weight. The results showed that the HCØ achieved higher BM, however, absolute HM did not differ post training. Irrespective of the diet, rats that were trained twice a week presented significantly greater increase in the AM. In general, the SC5 and HC5 groups showed higher HM, LV, RV, proportion of oxidative fibres and capillary density, compared to the sedentary and twice week trained groups. A higher proportion of injuries (splitting was noted in the HC2 and HC5 compared to SC2 and SC5. These results indicate that the frequency of training influenced the skeletal and heart adaptation and larger changes were observed in the 5x/week group, which ingested the standard diet. The 5x/week training groups also presented large amount of muscle fibres damage.

  6. Impact of artificial rearing systems on the developmental and reproductive fitness of the predatory bug, Orius laevigatus.

    Science.gov (United States)

    Bonte, Maarten; De Clercq, Patrick

    2010-01-01

    This study investigated the effect of several substrate types and moisture sources on the developmental and reproductive fitness of the zoophytophagous predator Orius laevigatus (Fieber) (Hemiptera: Anthocoridae) when fed a factitious prey (i.e. unnatural prey) Ephestia kuehniella (Zeller) eggs, or a meridic artificial diet based on hen's egg yolk. O. laevigatus is known to feed on plants as an alternative food source and to oviposit in plants. E. kuehniella eggs were superior to the artificial diet. Supplementary feeding on plant materials did not compensate for the nutritional shortcomings of the artificial diet. Survival rates showed that oviposition substrates such as bean pods or lipophilic surfaces such as wax paper and plastic were more suitable for rearing O. laevigatus than household paper. The use of green bean pods as a plant substrate did not have a beneficial effect on O. laevigatus. The results indicated that O. laevigatus can successfully complete its nymphal development and realize its full reproductive potential in the absence of plant material. However, plant materials would still be required for oviposition, unless a reliable and cost-effective artificial oviposition substrate were made available. The omission of plant materials from the rearing procedures may reduce production cost of this species and other heteropteran predators.

  7. 21 CFR 145.181 - Artificially sweetened canned pineapple.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Artificially sweetened canned pineapple. 145.181... § 145.181 Artificially sweetened canned pineapple. (a) Artificially sweetened canned pineapple is the food that conforms to the definition and standard of identity prescribed for canned pineapple by § 145...

  8. A randomized controlled trial comparing a standard postoperative diet with low-volume high-calorie oral supplements following colorectal surgery.

    Science.gov (United States)

    Sharma, M; Wahed, S; O'Dair, G; Gemmell, L; Hainsworth, P; Horgan, A F

    2013-07-01

    Postoperative oral nutritional supplementation is becoming a part of most patient care pathways. This study examined the effects of low-volume high-calorie prescribed supplemental nutrition on patient outcome following elective colorectal surgery. Patients undergoing elective colorectal resections were randomized to a prescribed nutritional supplementation group (SG) [standard diet + 6 × 60 ml/day of Pro-Cal (60 ml = 200 kcal + 4 g protein)] or conventional postoperative diet group (CG) (standard diet alone). Preoperative and daily postoperative hand-grip strengths were measured using a grip dynamometer after randomization. Daily food intake, return of bowel activity, nausea score for the first 3 days and postoperative length of hospital stay (LOS) were prospectively recorded. Micro-diet standardized software was used to analyse food diaries. Nonparametric tests were used to analyse the data. Fifty-five patients were analysed (SG 28, CG 27). There was no difference in median preoperative and postoperative handgrip strengths at discharge within each group (SG 31.7 vs 31.7 kPa, P = 0.932; CG 28 vs 28.1 kPa, P = 0.374). The total median daily calorie intake was higher in SG than CG (SG 818.5 kcal vs CG 528 kcal; P = 0.002). There was no difference in median number of days to first bowel movement (SG 3 days vs CG 4 days, P = 0.096). The median LOS was significantly shorter in SG than CG (6.5 vs 9 days; P = 0.037). Prescribed postoperative high-calorie, low-volume oral supplements in addition to the normal dietary intake are associated with significantly better total daily oral calorie intake and may contribute to a reduced postoperative hospital stay. Colorectal Disease © 2013 The Association of Coloproctology of Great Britain and Ireland.

  9. Variability in diet composition and dynamics of radiocaesium in moose

    International Nuclear Information System (INIS)

    Palo, R.T.; Wallin, K.

    1996-01-01

    1. Moose is the most important game species in Sweden and the fall-out after the Chernobyl accident has severely affected hunting of this animal. Nine years after the accident many animals in areas that received high deposition still show activity concentrations that exceed the limit for human consumption. Whilst the mechanism for uptake of 137 Cs in animals is fairly well known, the extent of variability in diet composition in wild animals is still puzzling and our ability to predict future trends in activity concentration of radionuclides limited. Studies on moose since the Chernobyl accident reveal considerable variation in 137 Cs-transfer between years and between individuals even in the same area. Differences in diet composition among individuals may explain the high degree of observed variability. Seventy per cent of the diet of moose in September is composed of Vaccinium myrtillus, Betula spp. and Salix spp. Significant differences between the proportion of birch and other components and species diversity within the diets among some years were measured. 2. We used a simple model, applying Monte Carlo simulations to create artificial diets for 137 Cs intake in moose. The model suggests that changes of diet composition or habitat use are the main reasons for the large variation of 137 Cs observed in moose. The variability in activity concentrations between different years obscure the decline expected from physical decay. The model shows that the standard deviation of 137 Cs activity concentration in moose meat declines with time as differences in activity concentration between food plants diminish. The coefficient of variation varies considerably among years in the real population and the model suggests that even at comparatively low mean values a large variation between individuals is expected. The model predicts that even after 30 years, the half-life of 137 Cs, a high mean level and a large variation could be possible

  10. Automatic food detection in egocentric images using artificial intelligence technology

    Science.gov (United States)

    Our objective was to develop an artificial intelligence (AI)-based algorithm which can automatically detect food items from images acquired by an egocentric wearable camera for dietary assessment. To study human diet and lifestyle, large sets of egocentric images were acquired using a wearable devic...

  11. Attractants in plant protein-based diets for the carnivorous largemouth bass Micropterus salmoides

    Directory of Open Access Journals (Sweden)

    Oliveira Ana Maria Barretto de Menezes Sampaio de

    2004-01-01

    Full Text Available Adding attractants can improve acceptability of artificial diets by carnivorous fish fry and fingerlings, increasing intake of unpalatable feeds and improving growth rate, while reducing feeding time and feeding wastes. This study aimed to evaluate the effects of levels of inclusion of different attractants in plant protein-based diets on the performance of largemouth bass Micropterus salmoides. Nine hundred juvenile largemouth bass (26.54 ± 1.53 g conditioned to accept dry, artificial feed were stocked in 60, 90-L polyethylene tanks (15 fish per group in a completely randomized design trial (n=3. Fish were fed two daily meals ad libitum at 7h00 and 17h00, for 13 days, with a diet (100% plant protein source containing either soluble fish protein - SFP (0.5, 1.0, 1.5, 2.0, 2.5, and 3.0%; FisharonTM - FA (0.02, 0.04, 0.06, 0.08, 0.10, 0.12%; fish silage - FS (1.0, 2.0, 3.0, 4.0, 5.0, and 6.0%; a positive control diet - pCD (10% fish meal and a negative control diet - nCD (basal diet without attractants. DL-methionine (98% and L-lysine (80% were added automatically by the formulation software to adjust available amino-acid profile of diets. Recorded performance data were: final weight, feed intake, weight gain and feed conversion ratio. Fish fed diet FA0.02 presented the best growth rate, best weight gain and best feed conversion ratio. Fish fed diets containing FS as attractant presented the poorest performance.

  12. Results Assessment of Intercomparison Exercise CSN/CIEMAT-2010 among Spanish National Laboratories of Environmental Radioactivity (Diet Ashes)

    International Nuclear Information System (INIS)

    Gasco, C.; Trinidad, J. A.; Llaurado, M.; Suarez, J. A.

    2012-01-01

    This report describes the results assessment of the intercomparison exercise among environmental radioactivity laboratories, organised by Spanish Regulatory Institution (CSN) and prepared and evaluated by UAB and CIEMAT respectively. The exercise has been carried out following the international standards ISO-43 and ISO/IUPAC that provide a useful guide to perform proficiency tests and inter-laboratories comparisons. The selected matrix for this year (2010) was a diet ash obtained from the ashing of a whole fresh diet (breakfast, lunch and dinner), that was enriched with artificial radionuclides (Cs-137, Co-60,Fe-55,Ni-63,Sr-90,Am-241,Pu-238,Pu-239,240 y C-14) and contained natural radionuclides (U-234, U-238, U-natural Th-230, Th-234, Ra-226, Ra-228, Pb-210, Pb-212, Pb-214, Bi-214, Ac-228, Tl-208, K-40) at environmental level of activity concentration. The z-score test was applied to determine how much the laboratories differ from the reference value. The reference value for this exercise was the median of the results from the different laboratories and their standard deviations to achieve a more complete and objective study of the laboratories performance. The participant laboratories have demonstrated a satisfactory quality level for measuring the natural and artificial radionuclides content in this matrix. The reference values obtained through the medians show a negative bias for Pb-210 and Th-234 when comparing to the given values of external qualified laboratories from ENEA and IRSN and positive one for K-40. (Author)

  13. Biological aspects of Argyrotaenia sphaleropa (Meyrick, 1909) (Lepidoptera: Tortricidae) in artificial diets with different protein sources; Aspectos biologicos de Argyrotaenia sphaleropa (Meyrick 1909) (Lepidoptera: Tortricidae) em dietas artificiais com diferentes fontes proteicas

    Energy Technology Data Exchange (ETDEWEB)

    Manfredi-Coimbra, Silvana [Universidade Federal de Pelotas (UFPel), RS (Brazil)]. E-mail: silvana.coimbra@pop.com.br; Garcia, Mauro Silveira; Loeck, Alci Enimar [Universidade Federal de Pelotas (UFPel), RS (Brazil). Faculdade de Agronomia Eliseu Maciel (FAEM). Dept. de Fitossanidade; Botton, Marcos [Empresa Brasileira de Pesquisa Agropecuaria (EMBRAPA), Bento Goncalves, RS (Brazil). Centro Nacional de Pesquisa de Uva e Vinho (CNPUV); Foresti, Josemar [Universidade Federal de Pelotas (UFPel), RS (Brazil). Faculdade de Agronomia Eliseu Maciel (FAEM). Entomologia

    2005-03-15

    Biology aspects of Argyrotaenia sphaleropa Meyrick fed on artificial diets with different protein sources were studied: D1-white bean, wheat germ, soybean protein and casein; D2-common bean and yeast and D3-common bean, yeast and wheat germ, evaluating the duration and viability of all developmental stages (egg, larval, prepupa and pupa) and of the total cycle (egg-adult), sex ratio, pupa weight, fecundity, longevity and life table of fertility. Tests were conducted in the laboratory at 25 {+-} 1 deg C, 65 {+-}10% RH and 14h of photophase. Duration of the egg stage was 6.6 days on all diets. The longest duration of larval and prepupal stages on D1 and pupal stages on D2, resulting in a longer duration of the total cycle on these two diets (30,9 and 30,8 days). The total viability was higher than 62% on all diets, and there was no statistical difference among the treatments. The number of instars was four or five on all treatments. The lowest fecundity was observed in D1. Based on the fertility life table, D3 was the most suitable diet for rearing A. sphaleropa, due to the lowest development time (T), the highest finite increasing rate (l), and total viability exceeding 75%. (author)

  14. Development and mass-rearing of cabbage pests (Plutella maculipennis and crocidolomia binotalis) on semisynthetic diets

    Energy Technology Data Exchange (ETDEWEB)

    Sjarief, Sri Hariani (National Atomic Energy Agency, Jakarta (Indonesia). Pasar Djumat Research Centre)

    1983-07-01

    Heavy damage to cabbage plantations in Indonesia as caused by plutella maculipennis and crocidolomia binotalis furnished economic justification of research on the sterile-male approach to eradication of this species. The sterile-male technique requires a mass-production of these insects, therefore studies were initiated on rearing larvae in artificial diets. A series of media based on biochemical and biological ingredients were tested. Larvae of the second instar were kept on artificial medium up to 14 days reaching the fourth instar (prepupae). The observation was carried out on the rates pupation, adult emergence and eggs production, continuous to their progenies. No morphological damaged are found on the diet-reared insects. A complete absence of cholesterol in the diet for crocidolomia binotalis brought on the emergence of non-fecund adults.

  15. Morphological study on dental caries induced in WBN/KobSlc rats (Rattus norvegicus) fed a standard laboratory diet.

    Science.gov (United States)

    Fukuzato, Yoko; Matsuura, Tetsuro; Ozaki, Kiyokazu; Matsuura, Masahiro; Sano, Tomoya; Nakahara, Yutaka; Kodama, Yasushi; Nakagawa, Akihito; Okamura, Sumie; Suido, Hirohisa; Torii, Kayo; Makino, Taketoshi; Narama, Isao

    2009-10-01

    In our previous studies, WBN/KobSlc was characterized as a rat strain in which only males began to develop pancreatitis, and then presented with diabetic symptoms. In the course of studying their pancreatic inflammation, we detected molar caries in prediabetic males feeding on a standard diet (CRF-1) widely used for experimental animals. The purpose of this study is to confirm whether the WBN/KobSlc strain is caries-susceptible to the diet reported to be non-cariogenic, and to examine the effect of a prediabetic condition on their dental caries. For a morphological study, 25 male WBN/KobSlc rats aged 3.2-7.8 months and 24 females of the same strain aged 3.3-6.6 months were used, along with 10 males and 10 females of 8.2-month-old F344 rats. Marked dental caries were detected in the mandibular molars of male and female WBN/KobSlc rats regardless of pancreatitis, although no similar changes were observed in any teeth of the F344 strain fed the same diet. Soft X-ray examination revealed that the caries began in the crown and progressed horizontally and vertically, and that a severe radiolucent lesion extensively expanded to the entire crown, corresponding to a macroscopically deleted molar. The caries had gradually developed mainly in the second mandibular molar from more than 3.5 months of age, while none were seen in any rats before that time. The WBN/KobSlc rats were caries-susceptible even to the standard laboratory diet, and pancreatitis was not directly associated with the onset of dental caries in this strain.

  16. Pasture v. standard dairy cream in high-fat diet-fed mice: improved metabolic outcomes and stronger intestinal barrier.

    Science.gov (United States)

    Benoit, Bérengère; Plaisancié, Pascale; Géloën, Alain; Estienne, Monique; Debard, Cyrille; Meugnier, Emmanuelle; Loizon, Emmanuelle; Daira, Patricia; Bodennec, Jacques; Cousin, Olivier; Vidal, Hubert; Laugerette, Fabienne; Michalski, Marie-Caroline

    2014-08-28

    Dairy products derived from the milk of cows fed in pastures are characterised by higher amounts of conjugated linoleic acid and α-linolenic acid (ALA), and several studies have shown their ability to reduce cardiovascular risk. However, their specific metabolic effects compared with standard dairy in a high-fat diet (HFD) context remain largely unknown; this is what we determined in the present study with a focus on the metabolic and intestinal parameters. The experimental animals were fed for 12 weeks a HFD containing 20 % fat in the form of a pasture dairy cream (PDC) or a standard dairy cream (SDC). Samples of plasma, liver, white adipose tissue, duodenum, jejunum and colon were analysed. The PDC mice, despite a higher food intake, exhibited lower fat mass, plasma and hepatic TAG concentrations, and inflammation in the adipose tissue than the SDC mice. Furthermore, they exhibited a higher expression of hepatic PPARα mRNA and adipose tissue uncoupling protein 2 mRNA, suggesting an enhanced oxidative activity of the tissues. These results might be explained, in part, by the higher amounts of ALA in the PDC diet and in the liver and adipose tissue of the PDC mice. Moreover, the PDC diet was found to increase the proportions of two strategic cell populations involved in the protective function of the intestinal epithelium, namely Paneth and goblet cells in the small intestine and colon, compared with the SDC diet. In conclusion, a PDC HFD leads to improved metabolic outcomes and to a stronger gut barrier compared with a SDC HFD. This may be due, at least in part, to the protective mechanisms induced by specific lipids.

  17. Storage stability of standard and diet figs canned in syrup

    Directory of Open Access Journals (Sweden)

    Priscilla Kárim CAETANO

    Full Text Available Abstract The current study aimed to evaluate the physicochemical, microbiological and sensory quality of traditional and diet figs canned in syrup, as well as verify their storage stability. Therefore, it was used green figs from the cultivar Roxo de Valinhos. Two treatments were held: standard sucrose syrup and sweetener blends: sodium cyclamate, sucralose and sodium saccharin. The syrups were previously prepared; being 25 °Brix for sucrose syrup; and by dividing the quantity of sucrose potency (100 to the blend of sweeteners potency (125 for sweetener blends. The products were stored at room temperature for 180 days and evaluated once a month through pH, soluble solids, titratable acidity, texture, vacuum and sensory evaluation (i.e. affective test; except for the commercial sterility test that was conducted at 0 to 180 days. Both canned figs in syrup showed no significant difference for pH, titratable acidity, soluble solids, vacuum and texture; therefore, both were considered commercially sterile and kept their sensory characteristics throughout storage.

  18. Artificial humidification for the mechanically ventilated patient

    OpenAIRE

    Selvaraj, Nelson

    2010-01-01

    Caring for patients who are mechanically ventilated poses many\\ud challenges for critical care nurses. It is important to humidify the\\ud patient’s airways artificially to prevent complications such as\\ud ventilator-associated pneumonia. There is no gold standard to\\ud determine which type of humidification is best for patients who\\ud are artificially ventilated. This article provides an overview of\\ud commonly used artificial humidification for mechanically ventilated\\ud patients and discuss...

  19. The development and mass-rearing of cabbage pests (Plutella maculipennis and crocidolomia binotalis) on semisynthetic diets

    International Nuclear Information System (INIS)

    Sjarief, Sri Hariani

    1983-01-01

    Heavy damage to cabbage plantations in Indonesia as caused by plutella maculipennis and crocidolomia binotalis furnished economic justification of research on the sterile-male approach to eradication of this species. The sterile-male technique requires a mass-production of these insects, therefore studies were initiated on rearing larvae in artificial diets. A series of media based on biochemical and biological ingridients were tested. Larvae of the second instar were kept on artificial medium up to 14 days reaching the fourth instar (prepupae). The observation was carried out on the rates pupation, adult emergence and eggs production, continuoous to their progenies. No morphological damaged are found on the diet-reared insects. A complete absence of cholesterol in the diet for crocidolomia binotalis brought on the emergence of non-fecund adults. (author)

  20. Long-term characterization of the diet-induced obese and diet-resistant rat model

    DEFF Research Database (Denmark)

    Madsen, Andreas Nygaard; Hansen, Gitte; Paulsen, Sarah Juel

    2010-01-01

    , namely the selectively bred diet-induced obese (DIO) and diet-resistant (DR) rat strains. We show that they constitute useful models of the human obesity syndrome. DIO and DR rats were fed either a high-energy (HE) or a standard chow (Chow) diet from weaning to 9 months of age. Metabolic characterization......, the results underscore the effectiveness of GLP-1 mimetics both as anti-diabetes and anti-obesity agents....

  1. THE USE OF SEAWORM MEAL IN MATURATION DIET AS PARTIAL SUBSTITUTION OF FRESH DIET FOR POND REARED TIGER SHRIMP BROODSTOCK

    Directory of Open Access Journals (Sweden)

    Asda Laining

    2014-12-01

    Full Text Available The purpose of this experiment was to evaluate the effects of using seaworm meal in artificial diet as partial substitution of freshfeed for maturation of tiger shrimp. This experiment started by growing-out tiger shrimp with initial weight around 60 g for four months until reaching maturation phase where shrimp weight were over 90 g for female. Tiger shrimp was selected and stocked into 10 ton concrete tank with stocking density of 50 shrimps with ratio of female : male of 1:1. Dietary treatments were different levels of seaworm meal at 0% (SW0, 10% (SW10 and 20% (SW20. SW0 was positive control without seaworm meal but breeder was fed with frozen seaworm. Test diets were fed as a combination of 60% test pellet and 40% fresh feed. Artificial insemination was carried out for all females before ablation to obtain fertile eggs. Results showed that after ablation, number of female matured was highest in group fed SW10 (13 breeders and the lowest in female fed control group (7 breeders. Number of female spawned was also highest in female fed SW10 and the lowest was in positive control. Fecundity was very low in all treatments ranged from 12,000-79,700 eggs/spawn. Even though female bearing spermatophore through insemination, number of spawning hatched was very low, only three spawned in each of SW0 and SW10 and two spawned in SW20. Based on number of breeders matured and spawning rate, breeder fed with SW10 gave better performance than other two diets. Technique of artificial insemination needs to be improved to increase the number of fertile eggs.

  2. Habitat-specific density and diet of rapidly expanding invasive red lionfish, Pterois volitans, populations in the northern Gulf of Mexico.

    Directory of Open Access Journals (Sweden)

    Kristen A Dahl

    Full Text Available Invasive Indo-Pacific red lionfish, Pterois volitans, were first reported in the northern Gulf of Mexico (nGOM in summer 2010. To examine potential impacts on native reef fish communities, lionfish density and size distributions were estimated from fall 2010 to fall 2013 with a remotely operated vehicle at natural (n = 16 and artificial (n = 22 reef sites. Lionfish (n = 934 also were sampled via spearfishing to examine effects of habitat type, season, and fish size on their diet and trophic ecology. There was an exponential increase in lionfish density at both natural and artificial reefs over the study period. By fall 2013, mean lionfish density at artificial reefs (14.7 fish 100 m(-2 was two orders of magnitude higher than at natural reefs (0.49 fish 100 m(-2, and already was among the highest reported in the western Atlantic. Lionfish diet was significantly different among habitats, seasons, and size classes, with smaller (<250 mm total length fish consuming more benthic invertebrates and the diet of lionfish sampled from artificial reefs being composed predominantly of non-reef associated prey. The ontogenetic shift in lionfish feeding ecology was consistent with δ15N values of white muscle tissue that were positively related to total length. Overall, diet results indicate lionfish are generalist mesopredators in the nGOM that become more piscivorous at larger size. However, lionfish diet was much more varied at artificial reef sites where they clearly were foraging on open substrates away from reef structure. These results have important implications for tracking the lionfish invasion in the nGOM, as well as estimating potential direct and indirect impacts on native reef fish communities in this region.

  3. Antibiotic inclusion in the diet did not alter the standardized ileal digestible tryptophan to lysine ratio for growing pigs

    Science.gov (United States)

    Two 21-d experiments were conducted to determine the optimum standard ileal digestible (SID) Trp:Lys ratio in growing pigs fed diets supplemented with or without an antibiotic. The primary response variables in both experiments were ADG, ADFI, G:F and plasma urea N (PUN) concentrations with the opti...

  4. Switching adolescent high-fat diet to adult control diet restores neurocognitive alterations

    Directory of Open Access Journals (Sweden)

    Chloe Boitard

    2016-11-01

    Full Text Available In addition to metabolic and cardiovascular disorders, obesity is associated with adverse cognitive and emotional outcomes. Its growing prevalence in adolescents is particularly alarming since this is a period of ongoing maturation for brain structures (including the hippocampus and amygdala and for the hypothalamic-pituitary-adrenal (HPA stress axis, which is required for cognitive and emotional processing. We recently demonstrated that adolescent, but not adult, high-fat diet (HF exposure leads to impaired hippocampal function and enhanced amygdala function through HPA axis alteration (Boitard et al., 2014; Boitard et al., 2012; Boitard et al., 2015. Here, we assessed whether the effects of adolescent HF consumption on brain function are permanent or reversible. After adolescent exposure to HF, switching to a standard chow diet restored levels of hippocampal neurogenesis and normalized enhanced HPA axis reactivity, amygdala activity and avoidance memory. Therefore, while the adolescent period is highly vulnerable to the deleterious effects of diet-induced obesity, adult exposure to a standard diet appears sufficient to reverse alterations of brain function.

  5. Engineering Technology Of Fish Farming Floating Nets Cages On Polka Dot Grouper (Cromileptes Altivelis) Used Artificial Feed Enriched Phytase Enzyme

    Science.gov (United States)

    Samidjan, Istiyanto; Rachmawati, Diana

    2018-02-01

    One solution is to utilize engineering technology cultivation floating cage net polka dot grouper (ducker grouper), which is given artificial feed enriched with phytase enzymes. The objectives of this study was to examine the use of technology engineering floating net on ducker grouper on artificial feed that is enriched with different dose phytase enzymes to accelerate growth and survival. The research method used ducker grouper fish size 15,5 ± 0,5 cm in the net cages unit (1 m x 1 m x 1 m), 250 fish per cage, using 12 cages. Each net-cages was made of polyethylens netting, mesh size 12.5 mm. with complete randomized design (CRD) 4 treatment and 3 replication were feed Artificial enriched of phytase enzyme with the doses of A (0 FTU · kg-1 diet), B (200 FTU · kg-1 diet), C (500 FTU · kg-1 diet), and D (800 FTU · kg-1 diet) phytase enzyme. Feed was given 2 times a day in the morning and afternoon with 5% biomass per day. Data includes the growth of absolute weight polka dot grouper, FCR, and survival rate analyzed variety and Test Tukey.The result of the research showed that the difference of artificial feeding enriched phytase enzyme significantly (P <0,05) to growth, food conversion ratio (FCR), survival rete of polka dot grouper. The best treatment at C (500 mg / kg of feed) increase growth of absolute weight of 128.75 g, 1.75 (FCR), and a survival rate of 93.5%.

  6. Rearing Chrysomya megacephala on artificial diets composed of varying concentrations of albumin

    Directory of Open Access Journals (Sweden)

    Paloma Martins Mendonça

    2009-04-01

    Full Text Available Larvae of the blowfly Chrysomya megacephala were reared on an artificial diet composed of five different concentrations of albumin (2, 4, 6, 8 and 10% and the control group was fed on putrid bovine meat. No larvae developed in the 2 and 10% albumin concentrations. The period from newly hatched larvae to adults reared on 4, 6 and 8% albumin was 13.1, 13.1 and 13.6 days, respectively, whereas for the control group, it was 11.2 days. Concentrations of 4, 6 and 8% albumin proved viabile for larval periods of 29.3, 44.0 and 57.3%, respectively, whereas for the control group, it was 77.3%. Pupal viability was 77.3, 36.4 and 83.7%, while for the control group, it was 84.5%; the newly hatched larvae to adult viability was 21.3, 16.0 and 48.0%, respectively, and for the control group, it was 65.3%.O presente trabalho teve como objetivo avaliar o desenvolvimento pós-embrionário de Chrysomya megacephala (Fabricius, 1794 (Diptera: Calliphoridae em dietas artificiais à base de albumina nas concentrações de 2%, 4%, 6%, 8% e 10% de albumina e como controle foi utilizada a carne bovina moída putrefata. Não houve desenvolvimento nas dietas de concentração 2% e 10% de albumina. A duração do período de larva a adulto foi 13,1; 13,1 e 13,6 dias, respectivamente, e a do controle foi de 11,2 dias. As dietas artificiais nas concentrações 4, 6 e 8% de albumina apresentaram viabilidades larvais de 29,3; 44,0 e 57,3%, respectivamente e o controle 77,3%; as viabilidades de pupa foram 77,3; 36,4 e 83,7% e o controle 84,5%, respectivamente; as viabilidades de larva a adulto foram 21,3; 16,0 e 48,0% e o controle foi de 65,3%, respectivamente.

  7. Influence of the diet components on the symbiotic microorganisms community in hindgut of Coptotermes formosanus Shiraki.

    Science.gov (United States)

    Tanaka, Hideo; Aoyagi, Hideki; Shiina, Shunsuke; Shina, Syunsuke; Doudou, Yuri; Dodo, Yuri; Yoshimura, Tsuyoshi; Nakamura, Ryosuke; Uchiyama, Hiroo

    2006-08-01

    Artificial diet was developed for rearing of lower termites (workers) Coptotermes formosanus. C. formosanus was fed with either wood powder of Japanese red pine, cellulose, cellobiose, or glucose for 30 days. The effect of carbon sources in the diet on the structure and function of the symbiotic intestinal microbial community and on the physiological activity of C. formosanus was studied. Three symbiont protozoa, Pseudotrichonympha grassi, Holomastigotoides hartmanni, and Spirotrichonympha leidyi, were found in the hindgut of C. formosanus that fed on the diets containing carbon sources with high molecular weight (MW). However, when artificial diets containing carbohydrate with low MW were used, both P. grassi and H. hartmanni disappeared, and only few S. leidyi were alive. This suggested that both P. grassi and H. hartmanni play important roles in the digestion and utilization of carbohydrate with high MW. The denaturing gradient gel electrophoresis analysis of bacterial community in the hindgut of termites showed that the similarity between intestinal bacteria community in termites fed with diets containing high-MW carbon sources and those with low MW was only about 40%. It was apparent that changes in diets resulted to changes in intestinal microbial community, and this in turn affected cellulase activity in C. formosanus.

  8. A bioenergetics systems evaluation of ketogenic diet liver effects.

    Science.gov (United States)

    Hutfles, Lewis J; Wilkins, Heather M; Koppel, Scott J; Weidling, Ian W; Selfridge, J Eva; Tan, Eephie; Thyfault, John P; Slawson, Chad; Fenton, Aron W; Zhu, Hao; Swerdlow, Russell H

    2017-09-01

    Ketogenic diets induce hepatocyte fatty acid oxidation and ketone body production. To further evaluate how ketogenic diets affect hepatocyte bioenergetic infrastructure, we analyzed livers from C57Bl/6J male mice maintained for 1 month on a ketogenic or standard chow diet. Compared with the standard diet, the ketogenic diet increased cytosolic and mitochondrial protein acetylation and also altered protein succinylation patterns. SIRT3 protein decreased while SIRT5 protein increased, and gluconeogenesis, oxidative phosphorylation, and mitochondrial biogenesis pathway proteins were variably and likely strategically altered. The pattern of changes observed can be used to inform a broader systems overview of how ketogenic diets affect liver bioenergetics.

  9. Standard representation and unified stability analysis for dynamic artificial neural network models.

    Science.gov (United States)

    Kim, Kwang-Ki K; Patrón, Ernesto Ríos; Braatz, Richard D

    2018-02-01

    An overview is provided of dynamic artificial neural network models (DANNs) for nonlinear dynamical system identification and control problems, and convex stability conditions are proposed that are less conservative than past results. The three most popular classes of dynamic artificial neural network models are described, with their mathematical representations and architectures followed by transformations based on their block diagrams that are convenient for stability and performance analyses. Classes of nonlinear dynamical systems that are universally approximated by such models are characterized, which include rigorous upper bounds on the approximation errors. A unified framework and linear matrix inequality-based stability conditions are described for different classes of dynamic artificial neural network models that take additional information into account such as local slope restrictions and whether the nonlinearities within the DANNs are odd. A theoretical example shows reduced conservatism obtained by the conditions. Copyright © 2017. Published by Elsevier Ltd.

  10. Produção de casulos de Bombyx mori L. alimentados com dietas artificiais e folhas “in natura” de Morus aba L. Production of cocoon of Bombyx mori L. fed on leaves of Morus aba L. and on artificial diets

    Directory of Open Access Journals (Sweden)

    Adriana Evangelista Rodrigues

    2001-05-01

    Full Text Available A utilização de dietas artificiais no Japão já é uma realidade, e no Brasil iniciam-se os estudos buscando encontrar um balanceamento que satisfaça as necessidades das larvas do bicho-da-seda, Bombyx mori (Lepidoptera. Desta forma, foram testados dois cultivares de amoreira como ingredientes das dietas, avaliando-se a qualidade do alimento, através do peso médio dos casulos e teor líquido de seda. As larvas foram separadas em parcelas, no início do 1º ínstar, onde já começaram a receber as dietas artificiais e as folhas “in natura”. Quando as larvas receberam folhas “in natura”, ao longo dos ínstares, apresentaram valores superiores para peso dos casulos. Por outro lado, quando receberam dietas artificiais, nos dois ínstares iniciais, não apresentaram diferença significativa para teor líquido de seda, quando comparadas com folhas “in natura”. Por fim, observou-se que a variedade Miura é melhor tanto como folha “in natura”, quanto como dieta artificial para peso de casulos.The utilization of artificial diets in Japan is fact and in Brazil the work is beginning to search meeting a balance form to satisfy the silkworm necessity, Bombyx mori (Lepidoptera. In such case, was tested two cultivars of mulberry in diets, to evaluate the quality of food trough mean cocoon weight and liquid silk. The larvae were separated in portion in the first instar begin and were to feed with diets and leaves “in nature”. When the silkworms were fed with leaves during five instars, showed cocoon weight high. When were fed diets in two inicial instars, showed that the silk liquid was good. The Miura variety is better in diets and leaves “in nature” for coccon weight.

  11. Effect of rearing diet on the infection rate in flies released for the control of tsetse populations by sterile males

    International Nuclear Information System (INIS)

    Maudlin, I.

    1990-01-01

    In areas where sleeping sickness is endemic, it is the practice of sterile insect technique (SIT) programmes to give sterilized males a bloodmeal before release into the wild in order to reduce the risk of these released flies acting as disease vectors. This strategy has been adopted because of experimental evidence which showed that it was essential to infect flies at their first feed to establish a Tripanosoma brucei gambiense or T. b rhodesiense infection in tsetse flies. The aim of the work was to test artificial tsetse diets produced in the IAEA Laboratory at Seibersdorf in order to determine whether they were as effective as whole blood in inhibiting T. brucei sensu lato (sl) infections in flies. Seven artificial diets were tested with T.b. rhodesiense; Glossina morsitans morsitans males were fed one meal of the diet and then starved for 3 days before the infective feed. None of these diets significantly altered the infection rate of the treated flies and the seven groups produced statistically homogeneous results, with a mean midgut rate of 16% (control flies fed pig blood: 17%). Flies infected as tenerals with the same trypanosome stock produced midgut rates of 61%. Three of the diets were also tested with a T. congolense stock. There were no significant differences between flies fed artificial (mean midgut infection rate: 15%) and whole blood diets (19%). G. m. morsitans infected as tenerals with this trypanosome stock produced midgut rates of 66%. As with T. brucei sl infections, teneral flies were far more likely to develop a T. congolense infection than fed flies; this result suggests that all the tsetse flies used in SIT programmes should be fed before release in order to reduce the risk both to man and his livestock. Artificial diets are as effective as whole blood in inhibiting trypanosome infections. The effect of bloodmeal on the fly infection rates is discussed in relation to lectin production in fed flies. (author). 13 refs, 2 tabs

  12. Habitat-specific density and diet of rapidly expanding invasive red lionfish, Pterois volitans, populations in the northern Gulf of Mexico.

    Science.gov (United States)

    Dahl, Kristen A; Patterson, William F

    2014-01-01

    Invasive Indo-Pacific red lionfish, Pterois volitans, were first reported in the northern Gulf of Mexico (nGOM) in summer 2010. To examine potential impacts on native reef fish communities, lionfish density and size distributions were estimated from fall 2010 to fall 2013 with a remotely operated vehicle at natural (n = 16) and artificial (n = 22) reef sites. Lionfish (n = 934) also were sampled via spearfishing to examine effects of habitat type, season, and fish size on their diet and trophic ecology. There was an exponential increase in lionfish density at both natural and artificial reefs over the study period. By fall 2013, mean lionfish density at artificial reefs (14.7 fish 100 m(-2)) was two orders of magnitude higher than at natural reefs (0.49 fish 100 m(-2)), and already was among the highest reported in the western Atlantic. Lionfish diet was significantly different among habitats, seasons, and size classes, with smaller (lionfish sampled from artificial reefs being composed predominantly of non-reef associated prey. The ontogenetic shift in lionfish feeding ecology was consistent with δ15N values of white muscle tissue that were positively related to total length. Overall, diet results indicate lionfish are generalist mesopredators in the nGOM that become more piscivorous at larger size. However, lionfish diet was much more varied at artificial reef sites where they clearly were foraging on open substrates away from reef structure. These results have important implications for tracking the lionfish invasion in the nGOM, as well as estimating potential direct and indirect impacts on native reef fish communities in this region.

  13. ARTIFICIAL BREEDING OF NERETVA SOFTMOUTH TROUT (Salmo obtusirostris Oxyrhincus Heckel, 1851

    Directory of Open Access Journals (Sweden)

    Dževad Handžar

    2015-06-01

    Full Text Available The paper presents an artificial breeding of softmouth trout (Salmo obtusirostris oxyrhynchus, which is one of the endemic species of fish Neretva basin and which is on the Red List of the International Union for Conservation of Nature (IUCN as endangered species facing extinction. Production of fry softmouth trout intended for restocking is very complex and complicated process, and in this paper, which is based on long experience in artificial breeding softmouth trout, we want to contribute to the conservation and breeding of native salmonid fish and aquaculture development of BiH. The paper describes the production technology and production phase, diet and food as well as the application of preventive and therapeutic measures in production. Key word - softmouth trout, artificial breeding, preventive and therapeutic measures

  14. The impact of chronic blackberry intake on the neuroinflammatory status of rats fed a standard or high-fat diet.

    Science.gov (United States)

    Meireles, Manuela; Marques, Cláudia; Norberto, Sónia; Fernandes, Iva; Mateus, Nuno; Rendeiro, Catarina; Spencer, Jeremy P E; Faria, Ana; Calhau, Conceição

    2015-11-01

    Neuroinflammation has been suggested as a central mediator of central nervous system dysfunction, including in dementia and neurodegenerative disease. Flavonoids have emerged as promising candidates for the prevention of neurodegenerative diseases and are thought to be capable of antiinflammatory effects in the brain. In the present study, the impact of a chronic intake of an anthocyanin extract from blackberry (BE) on brain inflammatory status in the presence or absence of a high-fat diet was investigated. Following intake of the dietary regimes for 17 weeks neuroinflammatory status in Wistar rat cortex, hippocampus and plasma were assessed using cytokine antibody arrays. In the cortex, intake of the high-fat diet resulted in an increase of at least 4-fold, in expression of the cytokine-induced neutrophil chemoattractant CINC-3, the ciliary neurotrophic factor CNTF, the platelet-derived growth factor PDGF-AA, IL-10, the tissue inhibitor of metalloproteinase TIMP-1 and the receptor for advanced glycation end products RAGE. BE intake partially decreased the expression of these mediators in the high-fat challenged brain. In standard-fed animals, BE intake significantly increased cortical levels of fractalkine, PDGF-AA, activin, the vascular endothelial growth factor VEGF and agrin expression, suggesting effects as neuronal growth and synaptic connection modulators. In hippocampus, BE modulates fractalkine and the thymus chemokine TCK-1 expression independently of diet intake and, only in standard diet, increased PDGF-AA. Exploring effects of anthocyanins on fractalkine transcription using the neuronal cell line SH-SY5Y suggested that other cell types may be involved in this effect. This is the first evidence, in in vivo model, that blackberry extract intake may be capable of preventing the detrimental effects of neuroinflammation in a high-fat challenged brain. Also, fractalkine and TCK-1 expression may be specific targets of anthocyanins and their metabolites on

  15. Mass production in liquid diet and radiosterilization of South American fruit fly Anastrepha sp.1 aff. fraterculus (Wied., 1830) (Diptera: Tephritidae); Criacao massal em dieta liquida e radioesterilizacao da mosca-sulamericana Anastrepha sp.1 aff. fraterculus (Wied., 1830) (Diptera: Tephritidae)

    Energy Technology Data Exchange (ETDEWEB)

    Kamiya, Aline Cristiane

    2010-07-01

    Both the biological control techniques as the Sterile Insect Technique (SIT), are used in many countries to control, suppress and even eradicate fruit flies and other pests in agriculture and public health. The use of such techniques minimizes the continuous employment of insecticides, protects the environment and conforms to standards for food safety. However, it is necessary to implement such programs, technology to produce millions of parasitoids and the pest in its own laboratory with biological quality similar to the insects found in nature and cost competitive with chemical control. The objectives of this study was to establish protocols for artificial rearing of A. sp. 1 aff. fraterculus in liquid larval diet that will achieve levels of mass production for a possible reduction in the cost of establishing and determining the dose of radiation sterilization of adult A. sp. 1 aff. fraterculus meeting the quality parameters required by the Sterile Insect Technique with insects from the creation of Radioentomology Laboratory of CENA/USP. Seven experimental diets compared to the conventional diet used in Radioentomology Lab. of CENA/USP, which was used as control. All seven diets have in common the exclusion of agar in its formulation. Only two of the diets tested were suitable for larval development of the fly, they compared with the standard diet, showed inferior results with respect to the volume of recovered larvae, pupae and weight of emergency, however, no significant differences regarding the periods of development , pupal recovery, sex ratio and longevity under stress. It is possible to replace the diet with agar for liquid diets for artificial creation of A. sp. 1 aff. fraterculus, reduced cost and greater convenience of handling, but due to their quality standards lower than the standard diet, more tests are needed especially regarding the adaptability of the insect to the new environment. To determine the sterilizing dose this study examined the

  16. Influence of caffeine consumption on 7,12-dimethylbenz(a)anthracene-induced mammary gland tumorigenesis in female rats fed a chemically defined diet containing standard and high levels of unsaturated fat.

    Science.gov (United States)

    Welsch, C W; DeHoog, J V

    1988-04-15

    The effect of caffeine (430-500 mg/liter of drinking water) on the initiation and promotion phases of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary gland tumorigenesis in female Sprague-Dawley rats fed a chemically defined diet containing standard (5%) or high (20%) levels of fat (corn oil) was examined. In the initiation studies, caffeine and the standard or high fat diet treatments were provided for 34 days, from 24-29 days of age to 58-63 days of age. Three days prior to termination of caffeine-fat diet treatments, each rat received a single dose of DMBA. In the promotion studies, caffeine and the standard or high fat diets were provided commencing 3 days after a single dose of DMBA (at 56-61 days of age) and until termination of the study. Caffeine consumption, during the initiation phase significantly (P less than 0.05) reduced mammary carcinoma multiplicity (number of tumors/rat), in rats fed either a standard or high fat diet. In the promotion studies, prolonged consumption of caffeine in rats fed either a standard or high fat diet did not significantly effect mammary carcinoma multiplicity. In the early stages of promotion, an apparent increase in mammary carcinoma multiplicity was observed; this increase in mammary carcinoma multiplicity did not, however, reach the 5% level of statistical probability. When caffeine was administered during both the initiation and promotion phases, no significant effect on mammary carcinoma multiplicity was observed. Treatment of rats during the initiation or promotion phases with caffeinated coffee (via drinking water) mimicked the mammary tumor modulating activities of caffeine. Decaffeinated coffee consumption did not effect either the initiation or promotion phases of this tumorigenic process. In both the initiation and promotion studies, caffeine and/or coffee consumption did not significantly affect the incidence of mammary carcinomas (percentage of rats bearing mammary carcinomas) or the mean latency period of

  17. Inorganic nutrients in natural and artificial food of Dacus oleae larvae (Diptera: Tephritidae)

    International Nuclear Information System (INIS)

    Manoukas, A.G.; Grimanis, A.; Mazomenos, B.

    1978-01-01

    Certain inorganic nutrients contained in the natural and artificial food of Dacus oleae larvae were determined by neutron activation analysis and spectrophotometry. The content of sodium, potassium, calcium, magnesium, manganese, iron, zinc, copper and phosporus was reported for the olive fruit mesocarp at three stages of maturity, brewer's yeast, soybean hydrolysate and roasted peanuts. Several differences were found between the inorganic nutrient content of the natural food (olive fruit) and artificial diet of D. oleae larvae. The differences which may be important in the nutrition and metabolism of this insect were estimated and discussed

  18. Elemental diets may reduce the risk of aspiration pneumonia in bedridden gastrostomy-fed patients.

    Science.gov (United States)

    Horiuchi, Akira; Nakayama, Yoshiko; Sakai, Ryosei; Suzuki, Manabu; Kajiyama, Masashi; Tanaka, Naoki

    2013-05-01

    Our clinical experience suggested that elemental diets were associated with a reduction in aspiration pneumonia among bedridden patients with percutaneous endoscopic gastrostomy (PEG). We compared the effects of elemental and standard liquid diets on the risk of clinical aspiration pneumonia and gastric emptying in bedridden patients receiving PEG feedings. Study 1: consecutive bedridden PEG patients received elemental diets or standard liquid diets in the same fashion. The frequency of defecation, diet aspirated from the trachea, and aspiration pneumonia during hospitalization were prospectively recorded. Study 2: a randomized, crossover trial using elemental or standard liquid diets containing (13)C sodium acetate as a tracer given to bedridden PEG patients who had experienced aspiration pneumonia. (13)C breath tests were performed to estimate gastric emptying. Study 1: 127 patients were enrolled, 60 with elemental and 67 with standard liquid diets. The diet was aspirated from the trachea in none (0%) with the elemental diet vs. 8 (11.9%) with standard liquid diets (P=0.0057); aspiration pneumonia developed none with the elemental diet vs. 5 (7.5%) with standard liquid diets (P=0.031) (number needed to treat 14, 95% confidence interval 7-85). Study 2: 19 patients were enrolled. The elemental diet was associated with a significant increase in the 10, 30 or 50% emptying (excretion) time (Pbedridden PEG patients. They may be preferred for bedridden PEG patients especially who have experienced aspiration pneumonia. Properly performed randomized-controlled trials are needed to prove this potential benefit.

  19. Novel artificial stool material for external quality assurance (EQA) on a fecal immunochemical test for hemoglobin (FIT): The confirmed utility of stable hemoglobin and an internal standard material.

    Science.gov (United States)

    Yasui, Ryota; Yamada, Miyu; Takehara, Shizuka; Sakurabayashi, Ikunosuke; Watanabe, Katsunori

    2018-04-16

    The fecal immunochemical test for hemoglobin (FIT), which detects lower gastrointestinal bleeding, is widely accepted for population-based colorectal cancer (CRC) screening programs. However, the FIT screening process has not been standardized yet, and standardizing the pre-analytical phase and establishing an external quality assurance (EQA) program compliant with ISO requirements is urgently needed. Although there have been various attempts to establish EQA materials suitable for FIT, no materials have yet been reported to have sufficient uniformity and acceptable immunochemical stability of hemoglobin (Hb). The Health Care Technology Foundation (HECTEF; Tokyo Japan) is now developing a ready-to-use artificial stool containing Hb and an internal standard, glycerol. Accordingly, we verified the adaptability and efficacy of this material for the evaluation of the specimen collection phase of FIT. This material uniformly contained both Hb and glycerol. The glycerol allowed us to estimate the weight of the collected artificial stool and to correct the Hb concentration with the estimated weight. Furthermore, the stability of both Hb and glycerol were confirmed to be sufficient for an EQA material under appropriate storage, in-use, repeated freeze-thaw, and heated conditions. These in-house performance characteristics suggest that HECTEF artificial stool is acceptable as an EQA material for FIT. Copyright © 2018 Elsevier B.V. All rights reserved.

  20. Artificial neural networks for decision-making in urologic oncology.

    Science.gov (United States)

    Anagnostou, Theodore; Remzi, Mesut; Lykourinas, Michael; Djavan, Bob

    2003-06-01

    The authors are presenting a thorough introduction in Artificial Neural Networks (ANNs) and their contribution to modern Urologic Oncology. The article covers a description of Artificial Neural Network methodology and points out the differences of Artificial Intelligence to traditional statistic models in terms of serving patients and clinicians, in a different way than current statistical analysis. Since Artificial Intelligence is not yet fully understood by many practicing clinicians, the authors have reviewed a careful selection of articles in order to explore the clinical benefit of Artificial Intelligence applications in modern Urology questions and decision-making. The data are from real patients and reflect attempts to achieve more accurate diagnosis and prognosis, especially in prostate cancer that stands as a good example of difficult decision-making in everyday practice. Experience from current use of Artificial Intelligence is also being discussed, and the authors address future developments as well as potential problems such as medical record quality, precautions in using ANNs or resistance to system use, in an attempt to point out future demands and the need for common standards. The authors conclude that both methods should continue to be used in a complementary manner. ANNs still do not prove always better as to replace standard statistical analysis as the method of choice in interpreting medical data.

  1. Role of Fatty Acid-Binding Protein 2 Ala54Thr Genotype on Weight Loss and Cardiovascular Risk Factors after a High-Protein/Low-Carbohydrate versus a Standard Hypocaloric Diet during 9 Months.

    Science.gov (United States)

    de Luis, Daniel Antonio; Izaola, Olatz; de la Fuente, Beatriz; Primo, David; Romero, Enrique

    2015-01-01

    It has been found that the expression of fatty acid-binding protein 2 gene mRNA is under dietary control. The polymorphism Ala54Thr of this protein was associated with high insulin resistance. The aim of our study was to investigate the influence of Thr54 polymorphism on metabolic response, weight loss and serum adipokine levels secondary to high-protein/low-carbohydrate vs. standard hypocaloric diets during 9 months. A population of 193 obese subjects was analyzed in a randomized trial. A nutritional evaluation was performed at the beginning and at the end of a 9-month period in which subjects received 1 of 2 diets (diet HP: high-protein/low-carbohydrate vs. diet S: standard diet). With both diets and in both genotype groups, body mass index, weight, fat mass, waist circumference, systolic blood pressure and leptin levels decreased. With both diets and only in wild genotype (diet HP vs. diet S), glucose (-6.2 ± 2.1 vs. -4.9 ± 2.0 mg/dl; p diet HP than HS. With both diets and only in the wild genotype, total cholesterol and LDL-total cholesterol levels decreased. Carriers of Thr54 allele have a different metabolic response after weight loss than wild type non-A carriers obese, with a lack of decrease of LDL-cholesterol, glucose, insulin levels and HOMA-R. © 2015 S. Karger AG, Basel.

  2. The Artificial Hamiltonian, First Integrals, and Closed-Form Solutions of Dynamical Systems for Epidemics

    Science.gov (United States)

    Naz, Rehana; Naeem, Imran

    2018-03-01

    The non-standard Hamiltonian system, also referred to as a partial Hamiltonian system in the literature, of the form {\\dot q^i} = {partial H}/{partial {p_i}},\\dot p^i = - {partial H}/{partial {q_i}} + {Γ ^i}(t,{q^i},{p_i}) appears widely in economics, physics, mechanics, and other fields. The non-standard (partial) Hamiltonian systems arise from physical Hamiltonian structures as well as from artificial Hamiltonian structures. We introduce the term `artificial Hamiltonian' for the Hamiltonian of a model having no physical structure. We provide here explicitly the notion of an artificial Hamiltonian for dynamical systems of ordinary differential equations (ODEs). Also, we show that every system of second-order ODEs can be expressed as a non-standard (partial) Hamiltonian system of first-order ODEs by introducing an artificial Hamiltonian. This notion of an artificial Hamiltonian gives a new way to solve dynamical systems of first-order ODEs and systems of second-order ODEs that can be expressed as a non-standard (partial) Hamiltonian system by using the known techniques applicable to the non-standard Hamiltonian systems. We employ the proposed notion to solve dynamical systems of first-order ODEs arising in epidemics.

  3. [Artificial sweeteners and diabetes: friends or foes?].

    Science.gov (United States)

    Tran, Christel; Jornayvaz, François R

    2015-06-03

    Sugary drinks consumption is associated with increased risk of obesity and type 2 diabetes. Thereby, artificial sweeteners (AS) consumption became increasingly popular and were introduced largely in our diet in order to reduce calorie intake and normalise blood glucose levels without altering our taste for "sweetness". However, the results of published studies on health outcomes secondary to AS intake, including type 2 diabetes risk, are inconsistent. The aim of this article is to focus on the role of AS in glucose homeostasis and diabetes onset.

  4. Diet Quality of Collegiate Athletes

    Science.gov (United States)

    Webber, Kelly; Stoess, Amanda Ireland; Forsythe, Hazel; Kurzynske, Janet; Vaught, Joy Ann; Adams, Bailey

    2015-01-01

    Background/Objectives: Collegiate athletes generally appear healthy according to weight for height and body fat standards. Despite the fact that there are well known connections between athletic performance and nutrition, little is known about the diets of collegiate athletes. The objective of this study was to determine the diet quality of 138…

  5. Monetary Diet Cost, Diet Quality, and Parental Socioeconomic Status in Spanish Youth.

    Directory of Open Access Journals (Sweden)

    Helmut Schröder

    Full Text Available Using a food-based analysis, healthy dietary patterns in adults are more expensive than less healthy ones; studies are needed in youth. Therefore, the objective of the present study was to determine relationships between monetary daily diet cost, diet quality, and parental socioeconomic status.Data were obtained from a representative national sample of 3534 children and young people in Spain, aged 2 to 24 years. Dietary assessment was performed with a 24-hour recall. Mediterranean diet adherence was measured by the KIDMED questionnaire. Average food cost was calculated from official Spanish government data. Monetary daily diet cost was expressed as euros per day (€/d and euros per day standardized to a 1000kcal diet (€/1000kcal/d.Mean monetary daily diet cost was 3.16±1.57€/d (1.56±0.72€/1000kcal/d. Socioeconomic status was positively associated with monetary daily diet cost and diet quality measured by the KIDMED index (€/d and €/1000kcal/d, p<0.019. High Mediterranean diet adherence (KIDMED score 8-12 was 0.71 €/d (0.28€/1000kcal/d more expensive than low compliance (KIDMED score 0-3. Analysis for nonlinear association between the KIDMED index and monetary daily diet cost per1000kcal showed no further cost increases beyond a KIDMED score of 8 (linear p<0.001; nonlinear p = 0.010.Higher monetary daily diet cost is associated with healthy eating in Spanish youth. Higher socioeconomic status is a determinant for higher monetary daily diet cost and quality.

  6. Is There an Optimal Diet for Weight Management and Metabolic Health?

    Science.gov (United States)

    Thom, George; Lean, Mike

    2017-05-01

    Individuals can lose body weight and improve health status on a wide range of energy (calorie)-restricted dietary interventions. In this paper, we have reviewed the effectiveness of the most commonly utilized diets, including low-fat, low-carbohydrate, and Mediterranean approaches, in addition to commercial slimming programs, meal replacements, and newly popularized intermittent fasting diets. We also consider the role of artificial sweeteners in weight management. Low-fat diets tend to improve low-density lipoprotein cholesterol the most, while lower-carbohydrate diets may preferentially improve triglycerides and high-density lipoprotein cholesterol. However, differences between diets are marginal. Weight loss improves almost all obesity-related co-morbidities and metabolic markers, regardless of the macronutrient composition of the diet, but individuals do vary in preferences and ability to adhere to different diets. Optimizing adherence is the most important factor for weight loss success, and this is enhanced by regular professional contact and supportive behavioral change programs. Maintaining weight losses in the long term remains the biggest challenge, and is undermined by an "obesogenic" environment and biological adaptations that accompany weight loss. Copyright © 2017 AGA Institute. Published by Elsevier Inc. All rights reserved.

  7. Effects of a high-protein/low-carbohydrate versus a standard hypocaloric diet on adipocytokine levels and cardiovascular risk factors during 9 months, role of rs6923761 gene variant of glucagon-like peptide 1 receptor.

    Science.gov (United States)

    de Luis, D A; Aller, R; Izaola, O; Romero, E

    2015-11-01

    The role of GLP-1 R variants on body weight response after dietary intervention is unclear. The aim was to investigate the role of this polymorphism on cardiovascular risk factors, adipokine levels and weight loss secondary to a high-protein/low-carbohydrate vs. standard hypocaloric diets during 9 months. 211 obese subjects were randomly allocated to one of these two diets for a period of 9 months; diet HP (high protein/low carbohydrate) and diet S (standard). Ninety-four patients (44.5%) had the genotype GG (wild group) and 117 (55.5%) patients had the next genotypes; GA (89 patients, 42.2%) or AA (28 patients, 13.3%) (mutant group). With both diets and in both genotype groups, body mass index, weight, fat mass, waist circumference and systolic blood pressure decreased. Anthropometric parameters were higher in non-A allele carriers than A allele carriers. With diet HP in both genotypes, LDL cholesterol, total cholesterol, leptin, insulin levels and HOMA-R decreased. With the diet S and only in wild genotype, the same parameters decreased, too. Our data showed a lack of association of rs6923761 GLP-1 R polymorphism with weight loss. Better anthropometric parameters in obese subjects with the mutant allele (A) of rs6923761 GLP-1 R polymorphism were observed. Total cholesterol, LDL cholesterol, insulin levels and HOMA-R decreased in all patients with both diets, although A allele carriers treated with standard diet did not show these changes.

  8. Bacterial diversity shift determined by different diets in the gut of the spotted wing fly Drosophila suzukii is primarily reflected on acetic acid bacteria

    KAUST Repository

    Vacchini, Violetta

    2016-11-25

    The pivotal role of diet in shaping gut microbiota has been evaluated in different animal models, including insects. Drosophila flies harbour an inconstant microbiota among which acetic acid bacteria (AAB) are important components. Here, we investigated the bacterial and AAB components of the invasive pest Drosophila suzukii microbiota, by studying the same insect population separately grown on fruit-based or non-fruit artificial diet. AAB were highly prevalent in the gut under both diets (90 and 92% infection rates with fruits and artificial diet, respectively). Fluorescent in situ hybridization and recolonization experiments with green fluorescent protein (Gfp)-labelled strains showed AAB capability to massively colonize insect gut. High-throughput sequencing on 16S rRNA gene indicated that the bacterial microbiota of guts fed with the two diets clustered separately. By excluding AAB-related OTUs from the analysis, insect bacterial communities did not cluster separately according to the diet, suggesting that diet-based diversification of the community is primarily reflected on the AAB component of the community. Diet influenced also AAB alpha-diversity, with separate OTU distributions based on diets. High prevalence, localization and massive recolonization, together with AAB clustering behaviour in relation to diet, suggest an AAB role in the D. suzukii gut response to diet modification. This article is protected by copyright. All rights reserved.

  9. RESULTS OF TESTS OF LIGHTNING-RODS WITH UNIVERSAL CLAMPS BY THE APERIODIC IMPULSES OF CURRENT OF ARTIFICIAL LIGHTNING WITH THE PEAK-TEMPORAL PARAMETERS RATIONED ON FOREIGN STANDARDS

    Directory of Open Access Journals (Sweden)

    M.I. Baranov

    2015-06-01

    Full Text Available Purpose. Test in obedience to the requirements of row of operating foreign standards of round metallic lightning-rods with the flat metallic universal clamps of the special type on firmness to direct action of аperiodic impulses of current of temporal form 10/350 μs by amplitude of 50 кА (N− class and 100 кА (H− class. Methodology. The order of leadthrough of these tests is certain the followings normative documents: International IEC 62305-1: 2010, Russian national GOST R IEC 62305-1-2010 and German national DIN EN 50164-1:2008 Standards. Results. Conducted on a powerful high-voltage pulsed current of artificial linear lightning with the peak-temporal parameters and admittances of test rationed on the indicated foreign standards rationed that all of the lightning-rods tested in collection with universal clamps, isolating holders and ceramic elements of roof of technical building were survive electrodynamics and electrothermal action of in-use single short blow of an artificial storm digit. Originality. First in domestic practice the similar model tests of lightning-rods are conducted with universal clamps, executed from different explorer materials, on firmness to flowing to on by it the indicated large impulsive currents of artificial lightning. Practical value. Real firmness to lightning of round copper and zincked steel lightning-rods is certain with the flat copper, zincked steel and non-rusting steel universal clamps of the special execution.

  10. Effects of cloned-cattle meat diet on reproductive parameters in pregnant rabbits.

    Science.gov (United States)

    Lee, Nam-Jin; Yang, Byoung-Chul; Hwang, Jae-Sik; Im, Gi-Sun; Ko, Yeoung-Gyu; Park, Eung-Woo; Seong, Hwan-Hoo; Park, Soo-Bong; Kang, Jong-Koo; Hwang, Seongsoo

    2010-03-01

    In this paper, we report on the effects of a diet containing cloned-cattle meat on the reproductive parameters in pregnant rabbits. The artificially inseminated rabbits (gestation day 0) were fed a diet containing 5% or 10% of normal or cloned-cattle meat during the gestation period. Rabbits fed commercial pellet (no additional supplementations) were used as the control. Supplementation of cloned-cattle meat diets did not have any toxicologically significant effects on reproductive performance in dams (body weight, clinical signs, organ weight, and cesarean section analysis). And it also did not affect on fetal development (body and placental weight, and external, visceral and skeletal findings) compared to the controls. The only difference was a food consumption in the first week of gestation for all meat-based diet groups (pmeat. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  11. LATENT RISK OF INTRODUCTION OF ARTIFICIAL MILK FORMULAS INTO INFANTS’ DIET: THE WAYS TO MINIMIZE NEGATIVE INFLUENCE

    Directory of Open Access Journals (Sweden)

    A. A. Davydovskaya

    2013-01-01

    Full Text Available Breast feeding has protective effect against certain diseases both in short and long-term prospects. On the contrary, artificial milk formulas (AMF and especially when early introduced, is associated with increased risk of infectious diseases and also is a risk factor for development of metabolic syndrome, type 1 diabetes mellitus and cardiovascular disorders in further life. The role of cow milk protein intolerance in transformation of alimentary allergy into other forms of atopic disorders («atopic» or «allergic march» is actively discussed in the article. Protective role of prolonged breast feeding is a subject of wide speculation in this article; the authors also open a question of significance of early diet for human health at the population level and consider possible ways to minimize negative influence of AMF introduction. It is well-known that different AMF are tolerated by children in different ways, in spite of the adjacency of «table» compositions. This fact most often is associated to protein components of milk formulas, as it is the most susceptible during processing of raw materials. Under the influence of high temperature and pressure, which are used by all manufacturers during AMF production, proteins are denatured. Denatured protein obtains certain characteristics, which can change its assimilation and tolerability. Awareness of these characteristics allows the key manufacturers to produce AMF with protein components of a high quality.

  12. Morphology of female reproductive tract of the predator Podisus nigrispinus (Dallas (Heteroptera: Pentatomidae fed on different diets

    Directory of Open Access Journals (Sweden)

    Walkymário de Paulo Lemos

    2005-01-01

    Full Text Available The morphology of the reproductive tract of Podisus nigrispinus (Dallas females fed with Alabama argillacea (Hübner larvae, artificial diet, Tenebrio molitor L. larvae or Musca domestica L. larvae were studied. The reproductive tract of females of this species presented yellow coloration and independent of the diet, each ovary had seven ovarioles joined through terminal filaments and forming a bunch shape structure. The histological data revealed that the ovary of P. nigrispinus was of meroistic telotrophic type, with each individual ovariole divided in a terminal filament, a tropharium (trophic chamber, a vitellarium, and a pedicel. The prey type affected the development and morphometry of these structures. Females of P. nigrispinus fed with 3rd or 5th instar larvae of cotton leafworm (A. argillacea presented developed ovaries with ovarioles showing a great number of oocytes in advanced stages of development. Females fed with artificial diet presented atrophic ovaries and ovarioles practically without oocytes. Females fed with T. molitor or M. domestica showed ovaries in intermediary stage of development. The central ovariole was longer in females fed with 5th instar larvae of cotton leafworm and shorter in those fed with artificial diet. Most developed oocytes were observed in ovaries of females fed with 5th or 3rd instar larvae of cotton leafworm, and the majority of atrophic oocytes were found in females fed with artificial diet.Este estudo apresenta a morfologia do sistema reprodutor feminino de Podisus nigrispinus (Dallas alimentado com larvas de Alabama argillacea (Hübner, Musca domestica L. e de Tenebrio molitor L. ou dieta artificial. As gônadas internas desse predador apresentaram coloração amarelada e, independente da dieta, cada ovário apresentou sete ovaríolos unidos pelos filamentos terminais em uma estrutura em forma de cacho. A análise histológica revelou que o ovário de P. nigrispinus é do tipo meroístico telotr

  13. Evaluation of the international standardized 24-h dietary recall methodology (GloboDiet) for potential application in research and surveillance within African settings.

    Science.gov (United States)

    Aglago, Elom Kouassivi; Landais, Edwige; Nicolas, Geneviève; Margetts, Barrie; Leclercq, Catherine; Allemand, Pauline; Aderibigbe, Olaide; Agueh, Victoire Damienne; Amuna, Paul; Annor, George Amponsah; El Ati, Jalila; Coates, Jennifer; Colaiezzi, Brooke; Compaore, Ella; Delisle, Hélène; Faber, Mieke; Fungo, Robert; Gouado, Inocent; El Hamdouchi, Asmaa; Hounkpatin, Waliou Amoussa; Konan, Amoin Georgette; Labzizi, Saloua; Ledo, James; Mahachi, Carol; Maruapula, Segametsi Ditshebo; Mathe, Nonsikelelo; Mbabazi, Muniirah; Mirembe, Mandy Wilja; Mizéhoun-Adissoda, Carmelle; Nzi, Clement Diby; Pisa, Pedro Terrence; El Rhazi, Karima; Zotor, Francis; Slimani, Nadia

    2017-06-19

    Collection of reliable and comparable individual food consumption data is of primary importance to better understand, control and monitor malnutrition and its related comorbidities in low- and middle-income countries (LMICs), including in Africa. The lack of standardised dietary tools and their related research support infrastructure remains a major obstacle to implement concerted and region-specific research and action plans worldwide. Citing the magnitude and importance of this challenge, the International Agency for Research on Cancer (IARC/WHO) launched the "Global Nutrition Surveillance initiative" to pilot test the use of a standardized 24-h dietary recall research tool (GloboDiet), validated in Europe, in other regions. In this regard, the development of the GloboDiet-Africa can be optimised by better understanding of the local specific methodological needs, barriers and opportunities. The study aimed to evaluate the standardized 24-h dietary recall research tool (GloboDiet) as a possible common methodology for research and surveillance across Africa. A consultative panel of African and international experts in dietary assessment participated in six e-workshop sessions. They completed an in-depth e-questionnaire to evaluate the GloboDiet dietary methodology before and after participating in the e-workshop. The 29 experts expressed their satisfaction on the potential of the software to address local specific needs when evaluating the main structure of the software, the stepwise approach for data collection and standardisation concept. Nevertheless, additional information to better describe local foods and recipes, as well as particular culinary patterns (e.g. mortar pounding), were proposed. Furthermore, food quantification in shared-plates and -bowls eating situations and interviewing of populations with low literacy skills, especially in rural settings, were acknowledged as requiring further specific considerations and appropriate solutions. An overall

  14. Monetary Diet Cost, Diet Quality, and Parental Socioeconomic Status in Spanish Youth

    Science.gov (United States)

    Ribas-Barba, Lourdes; Pérez-Rodrigo, Carmen; Bawaked, Rowaedh Ahmed; Fíto, Montserrat; Serra-Majem, Lluis

    2016-01-01

    Background Using a food-based analysis, healthy dietary patterns in adults are more expensive than less healthy ones; studies are needed in youth. Therefore, the objective of the present study was to determine relationships between monetary daily diet cost, diet quality, and parental socioeconomic status. Design and Methods Data were obtained from a representative national sample of 3534 children and young people in Spain, aged 2 to 24 years. Dietary assessment was performed with a 24-hour recall. Mediterranean diet adherence was measured by the KIDMED questionnaire. Average food cost was calculated from official Spanish government data. Monetary daily diet cost was expressed as euros per day (€/d) and euros per day standardized to a 1000kcal diet (€/1000kcal/d). Results Mean monetary daily diet cost was 3.16±1.57€/d (1.56±0.72€/1000kcal/d). Socioeconomic status was positively associated with monetary daily diet cost and diet quality measured by the KIDMED index (€/d and €/1000kcal/d, pdiet adherence (KIDMED score 8–12) was 0.71 €/d (0.28€/1000kcal/d) more expensive than low compliance (KIDMED score 0–3). Analysis for nonlinear association between the KIDMED index and monetary daily diet cost per1000kcal showed no further cost increases beyond a KIDMED score of 8 (linear pdiet cost is associated with healthy eating in Spanish youth. Higher socioeconomic status is a determinant for higher monetary daily diet cost and quality. PMID:27622518

  15. SuperSweet--a resource on natural and artificial sweetening agents.

    Science.gov (United States)

    Ahmed, Jessica; Preissner, Saskia; Dunkel, Mathias; Worth, Catherine L; Eckert, Andreas; Preissner, Robert

    2011-01-01

    A vast number of sweet tasting molecules are known, encompassing small compounds, carbohydrates, d-amino acids and large proteins. Carbohydrates play a particularly big role in human diet. The replacement of sugars in food with artificial sweeteners is common and is a general approach to prevent cavities, obesity and associated diseases such as diabetes and hyperlipidemia. Knowledge about the molecular basis of taste may reveal new strategies to overcome diet-induced diseases. In this context, the design of safe, low-calorie sweeteners is particularly important. Here, we provide a comprehensive collection of carbohydrates, artificial sweeteners and other sweet tasting agents like proteins and peptides. Additionally, structural information and properties such as number of calories, therapeutic annotations and a sweetness-index are stored in SuperSweet. Currently, the database consists of more than 8000 sweet molecules. Moreover, the database provides a modeled 3D structure of the sweet taste receptor and binding poses of the small sweet molecules. These binding poses provide hints for the design of new sweeteners. A user-friendly graphical interface allows similarity searching, visualization of docked sweeteners into the receptor etc. A sweetener classification tree and browsing features allow quick requests to be made to the database. The database is freely available at: http://bioinformatics.charite.de/sweet/.

  16. Association Between Artificially Sweetened Beverage Consumption During Pregnancy and Infant Body Mass Index.

    Science.gov (United States)

    Azad, Meghan B; Sharma, Atul K; de Souza, Russell J; Dolinsky, Vernon W; Becker, Allan B; Mandhane, Piushkumar J; Turvey, Stuart E; Subbarao, Padmaja; Lefebvre, Diana L; Sears, Malcolm R

    2016-07-01

    The consumption of artificial sweeteners has increased substantially in recent decades, including among pregnant women. Animal studies suggest that exposure to artificial sweeteners in utero may predispose offspring to develop obesity; however, to our knowledge, this has never been studied in humans. To determine whether maternal consumption of artificially sweetened beverages during pregnancy is associated with infant body mass index (BMI [calculated as weight in kilograms divided by height in meters squared]). This cohort study included 3033 mother-infant dyads from the Canadian Healthy Infant Longitudinal Development (CHILD) Study, a population-based birth cohort that recruited healthy pregnant women from 2009 to 2012. Women completed dietary assessments during pregnancy, and their infants' BMI was measured at 1 year of age (n = 2686; 89% follow-up). Statistical analysis for this study used data collected after the first year of follow-up, which was completed in October 2013. The data analysis was conducted in August 2015. Maternal consumption of artificially sweetened beverages and sugar-sweetened beverages during pregnancy, determined by a food frequency questionnaire. Infant BMI z score and risk of overweight at 1 year of age, determined from objective anthropometric measurements and defined according to World Health Organization reference standards. The mean (SD) age of the 3033 pregnant women was 32.4 (4.7) years, and their mean (SD) BMI was 24.8 (5.4). The mean (SD) infant BMI z score at 1 year of age was 0.19 (1.05), and 5.1% of infants were overweight. More than a quarter of women (29.5%) consumed artificially sweetened beverages during pregnancy, including 5.1% who reported daily consumption. Compared with no consumption, daily consumption of artificially sweetened beverages was associated with a 0.20-unit increase in infant BMI z score (adjusted 95% CI, 0.02-0.38) and a 2-fold higher risk of infant overweight at 1 year of age (adjusted odds ratio

  17. Influence of food diet in the radiosensitivity of spodoptera frugiperda smith abbot larvae

    International Nuclear Information System (INIS)

    Gonzalez, M.; Labrada, A.; Fundora, Z.; Herrera, A.

    1988-01-01

    To apply the traditional method in pest control it is needed to know the reaction capability of the insect in reference to radiations as well as the influence which can be exerted over it by different factors. The radiosensitivity of Spodoptera Frugiperda Smith Abbot larvae raised with two different diets (natural and artificial) was studied using doses between 20 and 100 Gy, in Co-60 gamma source with a dose power of 13.4 Gy/min survival, formation and dimensions of pupas, adult emergency and other interesting aspects were determined. The multiple analysis of results showed the influence of the food diet on radiosensitivity of larvae. results of both diets are statistically compared

  18. Consultants Group Meeting on Development of Cost-Effective Diets for Use in Mass Production of Tsetse Flies. Working Material

    International Nuclear Information System (INIS)

    2000-10-01

    The increasing demand for employing tsetse SIT for area-wide tsetse and trypanosomosis management programmes on mainland Africa has compelled the IAEA to concentrate on the development of semi-automated processes for standardising laborious and quality sensitive components of the sterile male mass production. The size of facilities required to produce the sterile males will continue to increase with time and demand. The current diet for tsetse is decontaminated vertebrate blood and it will need to be supplied to centres without access to a suitable local blood source. In view of the increasing demand for sterile male tsetse and uncertainty of obtaining high quality decontaminated blood locally, ways need to be explored to ensure availability of inexpensive, standard quality diets. Towards this goal a consultants group meeting on the development of cost-effective diets for tsetse was held at the IAEA headquarters in Vienna, Austria from 17 to 21 July 2000. The major objective of the consultants group meeting was to identify research that is needed to ensure the availability of large quantities of high quality diet for tsetse mass production. Seven papers were presented and discussed. A visit was made to the Entomology Unit, at the FAO/IAEA Agriculture and Biotechnology Laboratories, Seibersdorf to see the present tsetse rearing facility and the various steps of blood processing and quality assurance used in the evaluation of blood quality before use for colony feeding. The meeting noted that commercially available products are used to prepare standard diets for screwworm mass production. These products have not yet been adequately evaluated for tsetse. However, it is necessary to improve the current procedure applied to the use fresh blood. Possibilities of utilising commercially available dietary ingredients should also be explored. A three-step approach was proposed: Improvement and optimisation of the current blood collection, processing etc.; Use of additives

  19. Validity of electronic diet recording nutrient estimates compared to dietitian analysis of diet records: A randomized controlled trial

    Science.gov (United States)

    Background: Dietary intake assessment with diet records (DR) is a standard research and practice tool in nutrition. Manual entry and analysis of DR is time-consuming and expensive. New electronic tools for diet entry by clients and research participants may reduce the cost and effort of nutrient int...

  20. Dietary supplementation of grape skin extract improves glycemia and inflammation in diet-induced obese mice fed a Western high fat diet.

    Science.gov (United States)

    Hogan, Shelly; Canning, Corene; Sun, Shi; Sun, Xiuxiu; Kadouh, Hoda; Zhou, Kequan

    2011-04-13

    Dietary antioxidants may provide a cost-effective strategy to promote health in obesity by targeting oxidative stress and inflammation. We recently found that the antioxidant-rich grape skin extract (GSE) also exerts a novel anti-hyperglycemic activity. This study investigated whether 3-month GSE supplementation can improve oxidative stress, inflammation, and hyperglycemia associated with a Western diet-induced obesity. Young diet-induced obese (DIO) mice were randomly divided to three treatment groups (n = 12): a standard diet (S group), a Western high fat diet (W group), and the Western diet plus GSE (2.4 g GSE/kg diet, WGSE group). By week 12, DIO mice in the WGSE group gained significantly more weight (24.6 g) than the W (20.2 g) and S groups (11.2 g); the high fat diet groups gained 80% more weight than the standard diet group. Eight of 12 mice in the W group, compared to only 1 of 12 mice in the WGSE group, had fasting blood glucose levels above 140 mg/dL. Mice in the WGSE group also had 21% lower fasting blood glucose and 17.1% lower C-reactive protein levels than mice in the W group (P < 0.05). However, the GSE supplementation did not affect oxidative stress in diet-induced obesity as determined by plasma oxygen radical absorbance capacity, glutathione peroxidase, and liver lipid peroxidation. Collectively, the results indicated a beneficial role of GSE supplementation for improving glycemic control and inflammation in diet-induced obesity.

  1. Effects of a High-Protein/Low-Carbohydrate versus a Standard Hypocaloric Diet on Weight and Cardiovascular Risk Factors during 9 Months: Role of a Genetic Variation in the Cannabinoid Receptor Gene (CNR1) (G1359A Polymorphism).

    Science.gov (United States)

    de Luis, Daniel Antonio; Aller, Rocío; Izaola, Olatz; Díaz Soto, G; López Gómez, J J; Gómez Hoyos, E; Torres, B; Villar, A; Romero, Enrique

    2015-01-01

    We decided to investigate the role of this polymorphism on cardiovascular risk factors and weight loss secondary to a high-protein/low-carbohydrate vs. a standard hypocaloric diet (1,000 kcal/day) over a period of 9 months. A nutritional evaluation was performed at the beginning and at the end of a 9-month period in which subjects received 1 of 2 diets (diet HP: high protein/low carbohydrate vs. S: standard diet). One hundred and four patients (54.7%) had the genotype G1359G and 86 (45.3%) patients had G1359A (77 patients, 25.8%) or A1359A (9 patients, 3.7%) (A-allele-carriers). In subjects with both genotypes, the body mass index, weight, fat mass, waist circumference and systolic blood pressures decreased with both diets. After the diet type HP and in subjects with both genotypes, the glucose, leptin, total cholesterol, LDL-cholesterol, insulin and HOMA-R levels decreased. After diet S and in all subjects, the total cholesterol, LDL cholesterol and leptin levels decreased, too. Our interventional study didn't show a relationship between the rs1049353 CNR-1 polymorphism and body weight response after two different hypocaloric (low carbohydrate/high protein vs. standard) diets over a period of 9 months. However, a low-carbohydrate/high-protein diet for 9 months improved glucose metabolism in subjects with both genotypes. © 2015 S. Karger AG, Basel.

  2. Development of large intestinal attaching and effacing lesions in pigs in association with the feeding of a particular diet.

    OpenAIRE

    Neef, N A; McOrist, S; Lysons, R J; Bland, A P; Miller, B G

    1994-01-01

    Hysterotomy-derived piglets were kept in gnotobiotic isolators and artificially colonized at 7 days of age with an adult bovine enteric microflora. At 3 weeks of age, the pigs were transferred to conventional experimental accommodation and weaned, either onto a solid diet that had been associated with field cases of typhlocolitis in pigs or onto a solid control diet. At necropsy at 5 weeks of age, groups of pigs fed the diet associated with field cases of typhlocolitis were found to have deve...

  3. An artificial bee colony algorithm for the capacitated vehicle routing problem

    DEFF Research Database (Denmark)

    Szeto, W.Y.; Wu, Yongzhong; Ho, Sin C.

    2011-01-01

    This paper introduces an artificial bee colony heuristic for solving the capacitated vehicle routing problem. The artificial bee colony heuristic is a swarm-based heuristic, which mimics the foraging behavior of a honey bee swarm. An enhanced version of the artificial bee colony heuristic is also...... proposed to improve the solution quality of the original version. The performance of the enhanced heuristic is evaluated on two sets of standard benchmark instances, and compared with the original artificial bee colony heuristic. The computational results show that the enhanced heuristic outperforms...

  4. A systematic approach to standardize artificial aging of resin composite cements.

    Science.gov (United States)

    Blumer, Lukas; Schmidli, Fredy; Weiger, Roland; Fischer, Jens

    2015-07-01

    The aim of the investigation was to contribute to the ongoing discussion at the international standardization committee on how to artificially age dental resin composite cements. Indirect tensile strength (n=30) of a dual-cured resin composite cement (Panavia F2.0) was measured to evaluate the effect of water storage at 37°C or thermal cycling (5°C/55°C/1min) for up to 64 days. The influence of water temperature (5-65°C) after 16 days and the effect of 1 day water storage at 37°C prior to aging were assessed. Storage in air at 37°C served as control. Thermal cycling affected the indirect tensile strength most, followed by water storage at 55°C, whereas water storage at 37°C had only little influence. Major deterioration occurred before day 4 (≈6000 cycles). A 1-day pre-treatment by water storage at 37°C prior to thermal cycling attenuated the effect of aging. For the material investigated, thermal cycling for 4 days is the most efficient aging procedure. A 1-day water storage at 37°C prior to thermal cycling is recommended to allow complete polymerization. A 4-day water storage at 55°C may be considered as a viable alternative to thermal cycling. Copyright © 2015 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  5. GENETIC VARIATION IN THE BETA-3-ADRENORECEPTOR GENE (TRP64ARG POLYMORPHISM) AND THEIR INFLUENCE ON ANTHROPOMETRIC PARAMETERS AND INSULIN RESISTANCE AFTER A HIGH PROTEIN/LOW CARBOHYDRATE VERSUS A STANDARD HYPOCALORIC DIET.

    Science.gov (United States)

    de Luis, Daniel Antonio; Aller, Rocío; Izaola, Olatz; de la Fuente, Beatriz; Romero, Enrique

    2015-08-01

    the Trp64Arg variant in Beta receptor has been reported to be associated with increased body weight and insulin resistance Objective: the aim of our study was to investigate the influence of polymorphism (rs 4994) in Beta-3-adrenergic receptor gene on metabolic response and weight loss in a medium-term intervention study secondary's to a high protein/low carbohydrate vs. a standard hypocaloric diets (1000 kcal/day). a population of 284 obese subjects was analyzed in a randomized trial. A nutritional evaluation was performed at the beginning and at the end of a 9-month period in which subjects received 1 of 2 diets (diet HP: high protein/low carbohydrate vs diet S: standard diet). there were no significant differences between the positive effects (on weight, BMI, waist circumference, fat mass, systolic blood pressure and leptin levels) in either genotype group with both diets. With both diets and only in wild genotype (diet HP vs diet S), total cholesterol (-10.1 ± 3.9 mg/dl vs -10.1 ± 2.2 mg/dl;p>0.05), LDL cholesterol (-9.5 ± 2.1 mg/dl vs -8.5 ± 2.3 mg/dl;p>0.05) and triglycerides (-19.1 ± 2.1 mg/dl vs -14.3 ± 2.1 mg/dl;p>0.05) decreased. The improvement in these parameters was similar in subjects with diet HP than HS. With diet HP and only in wild genotype, insulin levels (-3.7 ± 1.9 UI/L;phypocaloric diets is the greatest in subjects with normal homozygous beta 3-AR gene. Improvement in total cholesterol, LDL-cholesterol, triglyceride, glucose, insulin and HOMA-R levels is better than in the heterozygous group. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  6. Controlling of bacterial flora contaminating animal diet and its components by gamma irradiation

    International Nuclear Information System (INIS)

    El-Fouly, M.Z.; El-Zawahry, Y.A.; Helal, G.A.; El-Hady, A.F.

    1991-01-01

    The total bacterial counts in complete diets were found to range between 10 3 -10 5 cells/g, which they ranged between 10 2 and 10 6 in the main components. One hundred and sixteen bacterial colonies were isolated from the animal diet samples and found to be gram positive belonging to three genera: Staphylococcus, Streptococcus and Bacillus. The most radioresistant bacteria isolated at 7.5 KGy were identified as B. megaterium, B. licheniformis, B. pumilus, B.circulans and B.laterosporus. The D 1 0 values for the bacteria contaminated the diet samples ranged between 928 Gy and 2199 Gy. Meanwhile, the D 1 0 values of staph.aureus and Strapt.faecalis artificially contaminated the diet were 400 Gy and 1136 Gy, respectively. It could be recommended from obtained results that dose level of 10 KGy is quite sufficient to eliminate all pathogens from animal diets or their components. In addition, it decreases the microbial count to minimum counts and hence increases the diet shelf life.1 fig.,4 tab

  7. Dynamic cardiomyoplasty using artificial muscle.

    Science.gov (United States)

    Suzuki, Yasuyuki; Daitoku, Kazuyuki; Minakawa, Masahito; Fukui, Kozo; Fukuda, Ikuo

    2008-01-01

    Dynamic cardiomyoplasty using latissimus dorsi muscle was previously used to compensate for congestive heart failure. Now, however, this method is not acceptable because the long-term result was not as expected owing to fatigue of the skeletal muscle. BioMetal fiber developed by Toki Corporation is one of the artificial muscles activated by electric current. The behavior of this fiber is similar to that of organic muscle. We made an artificial muscle like the latissimus dorsi using BioMetal fiber and tested whether we could use this new muscle as a cardiac supporting device. Testing one Biometal fiber showed the following performance: practical use maximal generative force was 30 g, exercise variation was 50%, and the standard driving current was 220 mA. We created a 4 x 12-cm tabular artificial muscle using 8 BioMetal fibers as a cardiac support device. We also made a simulation circuit composed of a 6 x 8-cm soft bag with unidirectional valves, reservoir, and connecting tube. The simulation circuit was filled with water and the soft bag was wrapped with the artificial muscle device. After powering the device electrically at 9 V with a current of 220 mA for each fiber, we measured the inside pressure and observed the movement of the artificial device. The artificial muscle contracted in 0.5 s for peak time and squeezed the soft bag. The peak pressure inside the soft bag was measured as 10 mmHg. Although further work will be needed to enhance the speed of deformability and movement simulating contraction, we conclude that artificial muscle may be potentially useful as a cardiac assistance device that can be developed for dynamic cardiomyoplasty.

  8. Short-term safety, tolerability and efficacy of a very low-calorie-ketogenic diet interventional weight loss program versus hypocaloric diet in patients with type 2 diabetes mellitus.

    Science.gov (United States)

    Goday, A; Bellido, D; Sajoux, I; Crujeiras, A B; Burguera, B; García-Luna, P P; Oleaga, A; Moreno, B; Casanueva, F F

    2016-09-19

    Brackground:The safety and tolerability of very low-calorie-ketogenic (VLCK) diets are a current concern in the treatment of obese type 2 diabetes mellitus (T2DM) patients. Evaluating the short-term safety and tolerability of a VLCK diet (diet), and 44 to the standard low-calorie diet. No significant differences in the laboratory safety parameters were found between the two study groups. Changes in the urine albumin-to-creatinine ratio in VLCK diet were not significant and were comparable to control group. Creatinine and blood urea nitrogen did not change significantly relative to baseline nor between groups. Weight loss and reduction in waist circumference in the VLCK diet group were significantly larger than in control subjects (both Pdiet group (Pdiet group declined at last follow-up. The interventional weight loss program based on a VLCK diet is most effective in reducing body weight and improvement of glycemic control than a standard hypocaloric diet with safety and good tolerance for T2DM patients.

  9. Total lipid in the broodstock diet did not affect fatty acid composition and quality of eggs of sea bass (Dicentrarchus labrax L.

    Directory of Open Access Journals (Sweden)

    José Mª Navas

    2001-03-01

    Full Text Available To determine whether an increase in the quantity of lipids ingested by sea bass (Dicentrarchus labrax broodstock could improve egg quality, three year-old sea bass were fed three different diets: a natural diet (Control group, and two artificial diets containing 10% or 17% of total lipids. In two consecutive reproductive seasons, the spawning results, the lipid classes and the fatty acid composition of the eggs were studied. No differences in the absolute content of lipids or in the percentage of different lipid classes were observed between the eggs from the three groups. Both experimental groups fed with the artificial diets produced eggs of poor quality, with low percentages of buoyancy and hatching. Those observed in the eggs from the Control Group were significantly higher (p> 0.01 than those of the experimental groups. The higher hatching rate of the eggs from the Control Group was associated with higher DHA:EPA and AA:EPA ratios. The data obtained showed that the fatty acid composition of the eggs was affected by the fatty acid composition of the diets but not by the total quantity of lipids administered to the broodstock.

  10. Artificial Consciousness or Artificial Intelligence

    OpenAIRE

    Spanache Florin

    2017-01-01

    Artificial intelligence is a tool designed by people for the gratification of their own creative ego, so we can not confuse conscience with intelligence and not even intelligence in its human representation with conscience. They are all different concepts and they have different uses. Philosophically, there are differences between autonomous people and automatic artificial intelligence. This is the difference between intelligence and artificial intelligence, autonomous versus a...

  11. Impact of Maternal Diet on Offspring Bone Fracture Risk During Childhood

    DEFF Research Database (Denmark)

    Petersen, Sesilje Elise Bondo

    , including maternal diet and vitamin D status. However, few studies have investigated whether these factors during pregnancy impact offspring bone health in short as well as in the long term. The overall objective of this thesis was to investigate epidemiologically whether maternal vitamin D status...... and dietary patterns in two prospective pregnancy cohorts, were associated with offspring risk of bone fractures in childhood. Overall, our studies provided limited support to the hypothesis that fetal bone health is programmed by the maternal vitamin D status and overall diet during pregnancy. However......, there were some indications of an increased risk for fractures when the mother consumed a Western diet and had high consumption of artificially sweetened soft drinks. Further, our results indicated that mid-pregnancy use of dietary supplements with high doses of vitamin D increased the risk for offspring...

  12. Open- and closed-formula laboratory animal diets and their importance to research.

    Science.gov (United States)

    Barnard, Dennis E; Lewis, Sherry M; Teter, Beverly B; Thigpen, Julius E

    2009-11-01

    Almost 40 y ago the scientific community was taking actions to control environmental factors that contribute to variation in the responses of laboratory animals to scientific manipulation. Laboratory animal diet was recognized as an important variable. During the 1970s, the American Institute of Nutrition, National Academy of Science, Institute of Laboratory Animal Resources, and Laboratory Animals Centre Diets Advisory Committee supported the use of 'standard reference diets' in biomedical research as a means to improve the ability to replicate research. As a result the AIN76 purified diet was formulated. During this same time, the laboratory animal nutritionist at the NIH was formulating open-formula, natural-ingredient diets to meet the need for standardized laboratory animal diets. Since the development of open-formula diets, fixed-formula and constant-nutrient-concentration closed-formula laboratory animal natural ingredient diets have been introduced to help reduce the potential variation diet can cause in research.

  13. Morphology of female reproductive tract of the predator Podisus nigrispinus (Dallas) (Heteroptera: Pentatomidae) fed on different diets

    OpenAIRE

    Lemos,Walkymário de Paulo; Ramalho,Francisco de Souza; Serrão,José Eduardo; Zanuncio,José Cola

    2005-01-01

    The morphology of the reproductive tract of Podisus nigrispinus (Dallas) females fed with Alabama argillacea (Hübner) larvae, artificial diet, Tenebrio molitor L. larvae or Musca domestica L. larvae were studied. The reproductive tract of females of this species presented yellow coloration and independent of the diet, each ovary had seven ovarioles joined through terminal filaments and forming a bunch shape structure. The histological data revealed that the ovary of P. nigrispinus was of mero...

  14. The feeding habit of sea turtles influences their reaction to artificial marine debris

    Science.gov (United States)

    Fukuoka, Takuya; Yamane, Misaki; Kinoshita, Chihiro; Narazaki, Tomoko; Marshall, Greg J.; Abernathy, Kyler J.; Miyazaki, Nobuyuki; Sato, Katsufumi

    2016-01-01

    Ingestion of artificial debris is considered as a significant stress for wildlife including sea turtles. To investigate how turtles react to artificial debris under natural conditions, we deployed animal-borne video cameras on loggerhead and green turtles in addition to feces and gut contents analyses from 2007 to 2015. Frequency of occurrences of artificial debris in feces and gut contents collected from loggerhead turtles were 35.7% (10/28) and 84.6% (11/13), respectively. Artificial debris appeared in all green turtles in feces (25/25) and gut contents (10/10), and green turtles ingested more debris (feces; 15.8 ± 33.4 g, gut; 39.8 ± 51.2 g) than loggerhead turtles (feces; 1.6 ± 3.7 g, gut; 9.7 ± 15.0 g). In the video records (60 and 52.5 hours from 10 loggerhead and 6 green turtles, respectively), turtles encountered 46 artificial debris and ingested 23 of them. The encounter-ingestion ratio of artificial debris in green turtles (61.8%) was significantly higher than that in loggerhead turtles (16.7%). Loggerhead turtles frequently fed on gelatinous prey (78/84), however, green turtles mainly fed marine algae (156/210), and partly consumed gelatinous prey (10/210). Turtles seemed to confuse solo drifting debris with their diet, and omnivorous green turtles were more attracted by artificial debris. PMID:27305858

  15. THE MEDITERRANEAN DIET AS A SUSTAINABLE FOOD SYSTEM

    Directory of Open Access Journals (Sweden)

    Ricardo Lopes

    2016-12-01

    Full Text Available Central theme in society these days, the diet went through several phases during the evolution of the human being. Currently human’s advanced civilizational, deplete resources, develops forms of reproduction and rapid growth of animals, genetically alter plants to make them more resilient and artificially prolongs life. All these factors lead to an overload in nature and revolve to a group of environmentalists and animal rights. Sustainability is part of everyday life of political and social discourse as the fundamental way to our relationship with the environment. Sustainable food systems are those that are able to survive over time, promoting sustainable use of resources and a balance in the economic, social and environmental aspects. Changing diet to the Mediterranean Diet would bring benefits: on the health level, with better nutrition and increased use of some processed products; economic, by encouraging the consumption of local and national production of products; social, with the creation of jobs in agriculture; and environmental, using organic production and the reduction of transportation needs. The Mediterranean Diet encourages a more balanced and healthy eating style, with great positive impact on the environment. With the globalization phenomena is was gradually lost, but is now being revived due to the awakening to health and ecological problems.

  16. Diet of the clupeid fish Platanichthys platana (Regan, 1917 in two different Brazilian coastal lagoons

    Directory of Open Access Journals (Sweden)

    Aguiaro Talita

    2003-01-01

    Full Text Available Platanichthys platana is considered a constant species in both Cabiúnas and Imboassica lagoons that are characterised by different marine and freshwater inputs, and anthropogenic influences. The stomach content analysis of P. platana captured between July 1991 and July 1993 revealed filamentous algae, detritus, eggs of benthic invertebrates, larvae of chironomids and bivalves as the main food sources in Imboassica lagoon. Small-sized cladocerans, copepods and shrimp larvae were the prevailing items in Cabiúnas lagoon. Seasonal food variations were noted for the fishes of Imboassica lagoon. Diet differences were highlighted within specimens lesser than 40 mm standard length in Imboassica lagoon, and were related to the increase of marine influence due to artificial sand barrier openings. Dissimilarities among size classes in relation to invertebrate larvae consumption were observed in fishes from Cabiúnas lagoon.

  17. Effect of semolina-jaggery diet on survival and development of Drosophila melanogaster

    Science.gov (United States)

    Chattopadhyay, Debarati; James, Joel; Roy, Debasish; Sen, Soumadeep; Chatterjee, Rishita; Thirumurugan, Kavitha

    2015-01-01

    Drosophila melanogaster is an ideal model organism for developmental studies. This study tests the potential of semolina-jaggery (SJ) diet as a new formulation for bulk rearing of flies. Semolina and jaggery are organic products obtained from wheat endosperm and cane sugar, respectively. Semolina is a rich source of carbohydrates and protein. Jaggery has a high content of dietary sugars. Moreover, preparation of semolina jaggery diet is cost-effective and easy. Thus, the current study aimed to compare survival and developmental parameters of flies fed the SJ diet to flies fed the standard cornmeal-sugar-yeast (CSY) diet. SJ diet enhanced survival of flies without affecting fecundity; male flies showed increased resistance to starvation. A higher number of flies emerged at F2 and F3 generation when fed the SJ diet than when fed the control CSY diet. SJ diet did not increase fly body weight and lipid percentage. Therefore, SJ diet can be used for bulk rearing of healthy flies at par with the standard cornmeal-sugar-yeast diet. PMID:26252611

  18. Effect of semolina-jaggery diet on survival and development of Drosophila melanogaster.

    Science.gov (United States)

    Chattopadhyay, Debarati; James, Joel; Roy, Debasish; Sen, Soumadeep; Chatterjee, Rishita; Thirumurugan, Kavitha

    2015-01-01

    Drosophila melanogaster is an ideal model organism for developmental studies. This study tests the potential of semolina-jaggery (SJ) diet as a new formulation for bulk rearing of flies. Semolina and jaggery are organic products obtained from wheat endosperm and cane sugar, respectively. Semolina is a rich source of carbohydrates and protein. Jaggery has a high content of dietary sugars. Moreover, preparation of semolina jaggery diet is cost-effective and easy. Thus, the current study aimed to compare survival and developmental parameters of flies fed the SJ diet to flies fed the standard cornmeal-sugar-yeast (CSY) diet. SJ diet enhanced survival of flies without affecting fecundity; male flies showed increased resistance to starvation. A higher number of flies emerged at F2 and F3 generation when fed the SJ diet than when fed the control CSY diet. SJ diet did not increase fly body weight and lipid percentage. Therefore, SJ diet can be used for bulk rearing of healthy flies at par with the standard cornmeal-sugar-yeast diet.

  19. Assessment of the effects of six standard rodent diets on binge-like and voluntary ethanol consumption in male C57BL/6J mice

    Science.gov (United States)

    Marshall, S. Alex; Rinker, Jennifer A.; Harrison, Langston K.; Fletcher, Craig A.; Herfel, Tina M.; Thiele, Todd E.

    2015-01-01

    Background In recent years much attention has been given to the lack of reproducibility in biomedical research, particularly in pre-clinical animal studies. This is a problem that also plagues the alcohol research field, particularly in consistent consumption in animal models of alcohol use disorders. One often overlooked factor that could affect reproducibility is the maintenance diet used in pre-clinical studies. Methods Herein, two well-established models of alcohol consumption, the “drinking in the dark” (DID) procedure and the continuous two-bottle choice paradigm (C2BC), were employed to determine the effects of diet on ethanol consumption. Male C57BL/6J were given one of six standard rodent-chow diets obtained from Purina LabDiet®, Inc. [St. Louis, MO; Prolab® RMH 3000] or Harlan Laboratories Inc. [Indianapolis, IN; Teklad Diets T.2916, T.2918, T.2920X, T.7912, or T.8940]. A separate group of animals were used to test dietary effects on ethanol pharmacokinetics and behavioral measures following intraperitoneal (IP) injections of various doses of ethanol. Results Mice eating Harlan diets T.2916 (H2916) and T.2920X (H2920) consumed significantly less ethanol and exhibited lower blood ethanol concentrations (BECs) during DID; however, during C2BC animals maintained on Harlan T.7912 (H7912) consumed more ethanol and had a higher ethanol preference than the other diet groups. Ethanol consumption levels did not stem from changes in alcohol pharmacokinetics, as a separate group of animals administered ethanol IP showed no difference in BECs. However, animals on Harlan diet T.2920X (H2920) were more sensitive to alcohol-induced locomotor activity in an open-field task. No diet dependent differences were seen in alcohol-induced sedation as measured with loss of righting reflex. Conclusions Although these data do not identify a specific mechanism, together they clearly show that the maintenance diet impacts ethanol consumption. It is incumbent upon the research

  20. Natural - synthetic - artificial!

    DEFF Research Database (Denmark)

    Nielsen, Peter E

    2010-01-01

    The terms "natural," "synthetic" and "artificial" are discussed in relation to synthetic and artificial chromosomes and genomes, synthetic and artificial cells and artificial life.......The terms "natural," "synthetic" and "artificial" are discussed in relation to synthetic and artificial chromosomes and genomes, synthetic and artificial cells and artificial life....

  1. An immune-modulating diet increases the regulatory T cells and reduces T helper 1 inflammatory response in Leishmaniosis affected dogs treated with standard therapy.

    Science.gov (United States)

    Cortese, Laura; Annunziatella, Mariangela; Palatucci, Anna Teresa; Lanzilli, Sarah; Rubino, Valentina; Di Cerbo, Alessandro; Centenaro, Sara; Guidetti, Gianandrea; Canello, Sergio; Terrazzano, Giuseppe

    2015-12-03

    Clinical appearance and evolution of Canine Leishmaniosis (CL) are the consequence of complex interactions between the parasite and the genetic and immunological backgrounds. We investigated the effect of an immune-modulating diet in CL. Dogs were treated with anti- Leishmania pharmacological therapy combined with standard diet (SD Group) or with the immune-modulating diet (IMMD Group). CD3+ CD4+ Foxp3+ Regulatory T cells (Treg) and CD3+ CD4+ IFN-γ + T helper 1 (Th1) were analyzed by flow cytometry. All sick dogs showed low platelet number at diagnosis (T0). A platelet increase was observed after six months (T6) SD Group, with still remaining in the normal range at twelve months (T12). IMMD Group showed an increase in platelet number becoming similar to healthy dogs at T6 and T12. An increase of CD4/CD8 ratio was revealed in SD Group after three months (T3), while at T6 and at T12 the values resembled to T0. The increase in CD4/CD8 ratio at T3 was maintained at T6 and T12 in IMMD Group. A reduction in the percentage of Treg of all sick dogs was observed at T0. A recovery of Treg percentage was observed only at T3 in SD Group, while this effect disappeared at T6 and T12. In contrast, Treg percentage became similar to healthy animals in IMDD Group at T3, T6 and T12. Sick dogs showed an increase of Th1 cells at T0 as compared with healthy dogs. We observed the occurrence of a decrease of Th1 cells from T3 to T12 in SD Group, although a trend of increase was observed at T6 and T12. At variance, IMMD Group dogs showed a progressive decrease of Th1 cells, whose levels became similar to healthy controls at T6 and T12. The immune-modulating diet appears to regulate the immune response in CL during the standard pharmacological treatment. The presence of nutraceuticals in the diet correlates with the decrease of Th1 cells and with the increase of Treg in sick dogs. Therefore, the administration of the specific dietary supplement improved the clinical response to the

  2. Flexible responses to visual and olfactory stimuli by foraging Manduca sexta: larval nutrition affects adult behaviour.

    Science.gov (United States)

    Goyret, Joaquín; Kelber, Almut; Pfaff, Michael; Raguso, Robert A

    2009-08-07

    Here, we show that the consequences of deficient micronutrient (beta-carotene) intake during larval stages of Manduca sexta are carried across metamorphosis, affecting adult behaviour. Our manipulation of larval diet allowed us to examine how developmental plasticity impacts the interplay between visual and olfactory inputs on adult foraging behaviour. Larvae of M. sexta were reared on natural (Nicotiana tabacum) and artificial laboratory diets containing different concentrations of beta-carotene (standard diet, low beta-carotene, high beta-carotene and cornmeal). This vitamin-A precursor has been shown to be crucial for photoreception sensitivity in the retina of M. sexta. After completing development, post-metamorphosis, starved adults were presented with artificial feeders that could be either scented or unscented. Regardless of their larval diet, adult moths fed with relatively high probabilities on scented feeders. When feeders were unscented, moths reared on tobacco were more responsive than moths reared on beta-carotene-deficient artificial diets. Strikingly, moths reared on artificial diets supplemented with increasing amounts of beta-carotene (low beta and high beta) showed increasing probabilities of response to scentless feeders. We discuss these results in relationship to the use of complex, multi-modal sensory information by foraging animals.

  3. Diet composition modifies embryotoxic effects induced by experimental diabetes in rats.

    Science.gov (United States)

    Giavini, E; Broccia, M L; Prati, M; Domenico Roversi, G

    1991-01-01

    Despite improvements in prenatal care, the incidence of congenital malformations in diabetic pregnancies is still 3-4 times higher than in normal pregnancies. These defects could be attributed to alterations of intrauterine environment due to disorder of the maternal metabolism. If this were true, the quality of food could play a role in diabetes-induced embryotoxicity. To check this hypothesis, female CD rats were made diabetic by injecting intravenously 50 mg/kg of streptozotocin 2 weeks before mating. From the first day of pregnancy they were divided into three groups and maintained on the following diets: (1) standard diet (Italiana Mangimi); (2) purified high protein diet (protein 55%, carbohydrates 25.5%, fat 7.5%, fiber 4.5%, ash 7.5%); (3) purified normoprotein diet (protein 19%, carbohydrates 62.5%, fat 7.5%, fiber 4%, ash 7%). Nondiabetic pregnant females fed with standard diet served as negative control. No significant differences were observed in blood glucose levels among the groups (range 410-500 mg/dl). The group fed on normoprotein diet showed at term of pregnancy: (1) higher rate of resorptions; (2) lower fetal weight; (3) higher frequency of major malformations than the groups fed standard and hyperproteic diets. Although we are not able at this time to discriminate between a protective effect of a diet with a high protein content and a disruptive effect of a diet containing high quantity of carbohydrates, the results of this trial support the hypothesis of a fuel-mediated teratogenesis in diabetic pregnancy.

  4. A low-fat diet improves peripheral insulin sensitivity in patients with Type 1 diabetes

    DEFF Research Database (Denmark)

    Rosenfalck, A M; Almdal, T; Viggers, L

    2006-01-01

    To compare the effects on insulin sensitivity, body composition and glycaemic control of the recommended standard weight-maintaining diabetes diet and an isocaloric low-fat diabetes diet during two, 3-month periods in patients with Type 1 diabetes.......To compare the effects on insulin sensitivity, body composition and glycaemic control of the recommended standard weight-maintaining diabetes diet and an isocaloric low-fat diabetes diet during two, 3-month periods in patients with Type 1 diabetes....

  5. Evaluation of the Susceptibility of the Pea Aphid, Acyrthosiphon pisum, to a Selection of Novel Biorational Insecticides using an Artificial Diet

    Science.gov (United States)

    Sadeghi, Amin; Van Damme, Els J.M.; Smagghe, Guy

    2009-01-01

    An improved technique was developed to assay the toxicity of insecticides against aphids using an artificial diet. The susceptibility of the pea aphid Acyrthosiphon pisum (Harris) (Hemiptera: Aphidoidea) was determined for a selection of novel biorational insecticides, each representing a novel mode of action. Flonicamid, a novel systemic insecticide with selective activity as feeding blocker against sucking insects, showed high toxicity against first-instar A. pisum nymphs with an LC50 of 20.4 μg/ml after 24 h, and of 0.24 µg/ml after 72 h. The toxicity was compared with another feeding blocker, pymetrozine, and the neonicotinoid, imidacloprid. In addition, four insect growth regulators were tested. The chitin synthesis inhibitor flufenoxuron, the juvenile hormone analogue pyriproxyfen, and the azadirachtin compound Neem Azal-T/S showed strong effects and reduced the aphid population by 50% after 3 days of treatment at a concentration of 7–9 µg/ml. The ecdysone agonist tested, halofenozide, was less potent. In conclusion, the improved aphid feeding apparatus can be useful as a miniature screening device for insecticides against different aphid pests. The present study demonstrated rapid and strong toxicity of flonicamid, and other biorational insecticides towards A. pisum. PMID:20053120

  6. The influence of components of diet on the symptoms of ADHD in children.

    Science.gov (United States)

    Konikowska, Klaudia; Regulska-Ilow, Bozena; Rózańska, Dorota

    2012-01-01

    In most children with ADHD the cause of the disease is not exactly known, and its etiology is multifactorial. The conventional treatment is based on the combination of behavioral and psychological therapy and the pharmacotherapy. The pharmacotherapy has a high effectiveness in ADHD treatment, but it is often associated with undesirable side effects, such as: loss of appetite and weight, growth inhibition, abdominal pain, headaches, sleeping problems and increased blood pressure. In the recent years, much attention was devoted to the issue of an appropriate diet in this disease, especially when the standard pharmacotherapy is not effective. The diet of pregnant and lactating woman, and child may have an impact on the development and deepening of the hyperkinetic syndrome. There is much evidence to indicate that it is linked to nutritional factors. Chronic deficiencies of certain minerals such as zinc, iron, magnesium and iodine and insufficient dietary intake of long-chain polyunsaturated fatty acids may have a significant impact on the development and deepening of the symptoms of ADHD in children. A crucial role in the diet of pregnant and lactating women, and child plays also polyunsaturated omega-3 fatty acids, mainly DHA, which are necessary for proper development and function of brain. Their chronic deficiency may contribute to increase risk of ADHD in children. The authors of several studies also demonstrated the positive impact of the elimination food products containing synthetic food additives, like artificial food dyes and preservatives on the behavior of children with ADHD. The beneficial effects brought also the elimination of food products, that are rich in salicylates. It was found that the intake of food products with a low glycemic index helps to reduce symptoms in some hyperactive children. Providing an appropriate supply of nutrients and minerals and elimination of certain food products from diet is especially important during intensive growth and

  7. The Effects of a Low-Carbohydrate Diet vs. a Low-Fat Diet on Novel Cardiovascular Risk Factors: A Randomized Controlled Trial

    Science.gov (United States)

    Hu, Tian; Yao, Lu; Reynolds, Kristi; Whelton, Paul K.; Niu, Tianhua; Li, Shengxu; He, Jiang; Bazzano, Lydia A.

    2015-01-01

    Increasing evidence supports a low-carbohydrate diet for weight loss and improvement in traditional cardiovascular disease (CVD) markers. Effects on novel CVD markers remain unclear. We examined the effects of a low-carbohydrate diet (low-fat diet (low-carbohydrate diet had significantly greater increases in adiponectin (mean difference in change, 1336 ng/mL (95% CI, 342 to 2330 ng/mL); p = 0.009) and greater decreases in intercellular adhesion molecule-1 concentrations (−16.8 ng/mL (−32.0 to −1.6 ng/mL); p = 0.031) than those on the low-fat diet. Changes in other novel CVD markers were not significantly different between groups. In conclusion, despite the differences in weight changes on diets, a low-carbohydrate diet resulted in similar or greater improvement in inflammation, adipocyte dysfunction, and endothelial dysfunction than a standard low-fat diet among obese persons. PMID:26393645

  8. [National consensus on the ketogenic diet].

    Science.gov (United States)

    Armeno, Marisa; Caraballo, Roberto; Vaccarezza, María; Alberti, M Julia; Ríos, Viviana; Galicchio, Santiago; de Grandis, Elizabeth S; Mestre, Graciela; Escobal, Nidia; Matarrese, Pablo; Viollaz, Rocío; Agostinho, Ariela; Díez, Cecilia; Cresta, Araceli; Cabrera, Analía; Blanco, Virginia; Ferrero, Hilario; Gambarini, Victoria; Sosa, Patricia; Bouquet, Cecilia; Caramuta, Luciana; Guisande, Silvina; Gamboni, Beatriz; Hassan, Amal; Pesce, Laura; Argumedo, Laura; Dlugoszewski, Corina; DeMartini, Martha G; Panico, Luis

    2014-09-01

    Epilepsy is a chronic disease with onset in infancy affecting 0.5-1% of the population. One third of the patients is refractory to antiepileptic drugs and they pose a challenge for the health care team. The ketogenic diet is an effective, non-pharmacological, alternative treatment for the management of refractory epilepsy. There is a need to establish guidelines for the adequate and increased use of the ketogenic diet in Spanish-speaking countries. The National Committee on the Ketogenic Diet, consisting of paediatric neurologists, clinical nutritionists, and dietitians, of the Argentine Society of Child Neurology has developed this consensus statement to standardize the use of the ketogenic diet based on the literature and clinical experience. Patient selection, pre-treatment family counseling, drug interactions, micronutrient supplementation, adverse effects, and discontinuation of the diet are discussed. The ketogenic diet is an effective treatment for children with refractory epilepsy. Education and collaboration of the patient and their family is essential. The patient should be managed by an experienced multidisciplinary team using a protocol. The formation of a national multidisciplinary team and the publication of this document provide possibilities for new centers to integrate the ketogenic diet into their treatment options.

  9. Mutagenicity assayed by dominant lethality testing in mice fed a combined gamma-irradiated diet

    International Nuclear Information System (INIS)

    Rupova, I.; Katsarova, Ts.; Bajrakova, A.; Baev, I.; Tencheva, S.

    1980-01-01

    Mice fed a combined gamma-irradiated diet were examined for a mutagenic effect using the dominant lethality test. Their feed contained the following irradiated ingredients: 20% maize, 10% dried plums, and 5% walnut kernels. Taking into account cycle duration in spermatogenesis and oogenesis, males were fed this special diet throughout 56 days, and females throughout 21 days. The experiments involved three animal groups: (1) fed the special diet containing irradiated ingredients; (2) fed the special diet but with the ingredients nonirradiated; and (3) fed standard vivarium diet. Matings to provide the first generation were between one parent fed the special diet and a partner fed standard diet. With an adequate number of implants examined on day 16 of gestation, embryonic death rate was not found to be increased; hence, induction of dominant lethality from consumption of irradiated diet failed to be demonstrated

  10. Administration of granulocyte-colony stimulating factor accompanied with a balanced diet improves cardiac function alterations induced by high fat diet in mice.

    Science.gov (United States)

    Daltro, Pâmela Santana; Alves, Paula Santana; Castro, Murilo Fagundes; Azevedo, Carine M; Vasconcelos, Juliana Fraga; Allahdadi, Kyan James; de Freitas, Luiz Antônio Rodrigues; de Freitas Souza, Bruno Solano; Dos Santos, Ricardo Ribeiro; Soares, Milena Botelho Pereira; Macambira, Simone Garcia

    2015-12-03

    High fat diet (HFD) is a major contributor to the development of obesity and cardiovascular diseases due to the induction of cardiac structural and hemodynamic abnormalities. We used a model of diabetic cardiomyopathy in C57Bl/6 mice fed with a HFD to investigate the effects of granulocyte-colony stimulating factor (G-CSF), a cytokine known for its beneficial effects in the heart, on cardiac anatomical and functional abnormalities associated with obesity and type 2 diabetes. Groups of C57Bl/6 mice were fed with standard diet (n = 8) or HFD (n = 16). After 36 weeks, HFD animals were divided into a group treated with G-CSF + standard diet (n = 8) and a vehicle control group + standard diet (n = 8). Cardiac structure and function were assessed by electrocardiography, echocardiography and treadmill tests, in addition to the evaluation of body weight, fasting glicemia, insulin and glucose tolerance at different time points. Histological analyses were performed in the heart tissue. HFD consumption induced metabolic alterations characteristic of type 2 diabetes and obesity, as well as cardiac fibrosis and reduced exercise capacity. Upon returning to a standard diet, obese mice body weight returned to non-obese levels. G-CSF administration accelerated the reduction in of body weight in obese mice. Additionally, G-CSF treatment reduced insulin levels, diminished heart fibrosis, increased exercise capacity and reversed cardiac alterations, including bradycardia, elevated QRS amplitude, augmented P amplitude, increased septal wall thickness, left ventricular posterior thickening and cardiac output reduction. Our results indicate that G-CSF administration caused beneficial effects on obesity-associated cardiac impairment.

  11. [Audit of artificial nutrition in an intensive care unit].

    Science.gov (United States)

    Blesa Malpica, A L; Salaverría Garzón, I; Prado López, L M; Simón García, M J; Reta Pérez, O; Ramos Polo, J

    2001-01-01

    To study compliance with an artificial nutrition protocol at an Intensive Care Unit. During a second stage and after introducing the modifications considered appropriate in the protocol, to verify its implementation and compare both series. REFERENCE POPULATION: All patients with artificial nutrition support were included. Artificial nutrition (AN) was deemed to be the dispensation of commercial preparations for enteral nutrition, formulas with amino acids and glucose and the parenteral provision of fat, including propofol in this case, even where it was the only source of energy. The provision of crystalloid solutions was not considered to be AN. The period of observation was two months in both cases. The provision of AN to all such patients was systematically recorded on a daily basis. After analysis of the first series, the members at the unit agreed to increase the nitrogen provision. A second series was recorded, with the data being collected for patients with AN during a similar period. The study of the first series revealed the provisions of energy and nitrogen were below theoretical levels (both in the corrected Harris-Benedict test and at the fixed prescription of 25 kcal/kg). In the second series, there was greater agreement between the theoretical values and the amounts actually received. The deviation in energy and nitrogen was significantly less in the second series. And although the total nitrogen load per patient did not reveal any differences, there were discrepancies in the daily provision per patient. On most days, the diet provided covered over 75% of the energy requirements. With parenteral nutrition on its own or in combination with enteral nutrition, the requirements of energy and nitrogen were exceeded. There were no differences between the two series. The type of provision was enteral on 55% of the days and parenteral on 18%. There was no difference in the type of provision between the two series, although there was a difference in the type

  12. Artificial intelligence

    CERN Document Server

    Hunt, Earl B

    1975-01-01

    Artificial Intelligence provides information pertinent to the fundamental aspects of artificial intelligence. This book presents the basic mathematical and computational approaches to problems in the artificial intelligence field.Organized into four parts encompassing 16 chapters, this book begins with an overview of the various fields of artificial intelligence. This text then attempts to connect artificial intelligence problems to some of the notions of computability and abstract computing devices. Other chapters consider the general notion of computability, with focus on the interaction bet

  13. The Dutch Healthy Diet Index : development, evaluation, and application

    NARCIS (Netherlands)

    Lee, van L.

    2014-01-01

    The Dutch Healthy Diet index – Development, Evaluation, and Application

    Linde van Lee

    Abstract

    Background: Dietary indices evaluate the conformity of an individual’s diet with pre-defined standards. Generally, dietary

  14. RS 10767664 gene variant in Brain Derived Neurotrophic Factor (BDNF) affect metabolic changes and insulin resistance after a standard hypocaloric diet.

    Science.gov (United States)

    de Luis, Daniel Antonio; Fernández Ovalle, H; Izaola, O; Primo, D; Aller, Rocío

    2018-02-01

    Role of BDNF variants on change in body weight and cardiovascular risk factors after weight loss remains unclear in obese patients. Our aim was to analyze the effects of rs10767664 BDNF gene polymorphism on body weight, cardiovascular risk factors and serum adipokine levels after a standard hypocaloric diet in obese subjects. A Caucasian population of 80 obese patients was analyzed before and after 3months on a standard hypocaloric diet. Fifty patients (62.5%) had the genotype AA and 30 (37.5%) subjects had the next genotypes; AT (25 patients, 31.3%) or TT (5 study subjects, 6.3%) (second group). In non T allele carriers, the decreases in weight-3.4±2.9kg (T allele group -1.7±2.0kg:p=0.01), BMI -1.5±0.2kg (T allele group -1.2±0.5kg:p=0.02), fat mass-2.3±1.1kg (T allele group -1.7±0.9kg:p=0.009), waist circumference-3.8±2.4cm (T allele group -2.1±3.1cm:p=0.008), triglycerides -13.2±7.5mg/dl (T allele group +2.8±1.2mg/dl:p=0.02), insulin -2.1±1.9mUI/L (T allele group -0.3±1.0mUI/L:p=0.01), HOMA-IR -0.9±0.4 (T allele group -0.1±0.8:p=0.01) and leptin -10.1±9.5ng/dl (T allele group -3.1±0.2ng/dl:p=0.01) were higher than T allele carriers. rs10767664 variant of BDNF gene modify anthropometric and biochemical changes after weight loss with a hypocaloric diet. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Improving diet sustainability through evolution of food choices: review of epidemiological studies on the environmental impact of diets.

    Science.gov (United States)

    Perignon, Marlène; Vieux, Florent; Soler, Louis-Georges; Masset, Gabriel; Darmon, Nicole

    2017-01-01

    The Food and Agriculture Organization defines sustainable diets as nutritionally adequate, safe, healthy, culturally acceptable, economically affordable diets that have little environmental impact. This review summarizes the studies assessing, at the individual level, both the environmental impact and the nutritional quality or healthiness of self-selected diets. Reductions in meat consumption and energy intake were identified as primary factors for reducing diet-related greenhouse gas emissions. The choice of foods to replace meat, however, was crucial, with some isocaloric substitutions possibly increasing total diet greenhouse gas emissions. Moreover, nutritional adequacy was rarely or only partially assessed, thereby compromising the assessment of diet sustainability. Furthermore, high nutritional quality was not necessarily associated with affordability or lower environmental impact. Hence, when identifying sustainable diets, each dimension needs to be assessed by relevant indicators. Finally, some nonvegetarian self-selected diets consumed by a substantial fraction of the population showed good compatibility with the nutritional, environmental, affordability, and acceptability dimensions. Altogether, the reviewed studies revealed the scarcity of standardized nationally representative data for food prices and environmental indicators and suggest that diet sustainability might be increased without drastic dietary changes. © The Author(s) 2016. Published by Oxford University Press on behalf of the International Life Sciences Institute.

  16. Improvement of Diet-induced Obesity by Ingestion of Mushroom Chitosan Prepared from Flammulina velutipes.

    Science.gov (United States)

    Miyazawa, Noriko; Yoshimoto, Hiroaki; Kurihara, Shoichi; Hamaya, Tadao; Eguchi, Fumio

    2018-02-01

    The anti-obesity effects of mushroom chitosan prepared from Flammulina velutipes were investigated using an animal model with diet-induced obesity. In this study, 5-week-old imprinting control region (ICR) mice were divided into six groups of 10 mice each and fed different diets based on the MF powdered diet (standard diet) for 6 weeks: standard diet control group, high-fat diet control group (induced dietary obesity) consisting of the standard diet and 20% lard, and mushroom chitosan groups consisting of the high-fat diet with mushroom chitosan added at 100, 500, 1,000, and 2,000 mg/kg body weight. On the final day of the experiment, mean body weight was 39.1 g in the high-fat control group and 36.3 g in the 2,000 mg/kg mushroom chitosan group, compared to 35.8 g in the standard diet control group. In the mushroom chitosan groups, a dose-dependent suppression of weight gain and marked improvements in serum triglycerides, total cholesterol, LDL-cholesterol, and HDL-cholesterol were found. The mushroom chitosan groups showed fewer and smaller fat deposits in liver cells than the high-fat diet control group, and liver weight was significantly reduced. Glutamic oxaloacetic transaminase (GOT) and glutamate pyruvic transaminase (GPT), which are indices of the hepatic function, all showed dose-dependent improvement with mushroom chitosan administration. These results suggested that mushroom chitosan acts to suppress enlargement of the liver from fat deposition resulting from a high-fat diet and to restore hepatic function. The lipid content of feces showed a marked increase correlated with the mushroom chitosan dose. These findings suggest the potential use of mushroom chitosan as a functional food ingredient that contributes to the prevention or improvement of dietary obesity by inhibiting digestion and absorption of fats in the digestive tract and simultaneously promotes lipolysis in adipocytes.

  17. Effect of an Enzyme Blend on the Performance, Diet Metabolizability, Phosphorous Retention, and Bone Mineralization of Broilers Fed Diets Containing Defatted Rice Bran

    Directory of Open Access Journals (Sweden)

    ML Moraes

    2015-06-01

    Full Text Available An experiment was conducted to evaluate the effect of an enzyme blend (EB on the performance, diet metabolizability, phosphorus (P retention, and bone mineralization of broilers fed diets containing 10% defatted rice bran (DRB. In total, 432 one- to 38-d-old male Cobb broilers were evaluated according to a completely randomized experimental design in 3 x 2 factorial arrangement. Three diets were tested with two nutrient reductions (NR in the matrix (standard diet; NR I of 75 kcal/kg ME, 0.1% Ca and 0.1% available P; and NR II of 100 kcal/kg ME, 0.1% Ca and 0.1% available P with or without the addition of an EB (200 g/t. The coefficients of total tract apparent retention (CTTAR of the diets and P retention were determined by collecting excreta during two periods (14 to 17 and 28 to 31 d. As expected, birds fed the standard diet had higher BW, BW gain, and G:F compared to birds on the NR diets. The EB did not show any positive effects on CTTAR or on performance; however, birds fed the EB retained 6.58% more P from d 14 to 17 (p ≤ 0.07 and 8.55% from d 28 to 31 (p < 0.05. Tibiotarsus ash percentage also increased by 2.45% (p ≤ 0.06 on d 38. In diets containing 10% DRB, the enzyme blend showed biological activity improving P retention and tibiotarsus mineralization.

  18. TRPV1 Channels and Gastric Vagal Afferent Signalling in Lean and High Fat Diet Induced Obese Mice.

    Directory of Open Access Journals (Sweden)

    Stephen J Kentish

    Full Text Available Within the gastrointestinal tract vagal afferents play a role in control of food intake and satiety signalling. Activation of mechanosensitive gastric vagal afferents induces satiety. However, gastric vagal afferent responses to mechanical stretch are reduced in high fat diet mice. Transient receptor potential vanilloid 1 channels (TRPV1 are expressed in vagal afferents and knockout of TRPV1 reduces gastro-oesophageal vagal afferent responses to stretch. We aimed to determine the role of TRPV1 on gastric vagal afferent mechanosensitivity and food intake in lean and HFD-induced obese mice.TRPV1+/+ and -/- mice were fed either a standard laboratory diet or high fat diet for 20wks. Gastric emptying of a solid meal and gastric vagal afferent mechanosensitivity was determined.Gastric emptying was delayed in high fat diet mice but there was no difference between TRPV1+/+ and -/- mice on either diet. TRPV1 mRNA expression in whole nodose ganglia of TRPV1+/+ mice was similar in both dietary groups. The TRPV1 agonist N-oleoyldopamine potentiated the response of tension receptors in standard laboratory diet but not high fat diet mice. Food intake was greater in the standard laboratory diet TRPV1-/- compared to TRPV1+/+ mice. This was associated with reduced response of tension receptors to stretch in standard laboratory diet TRPV1-/- mice. Tension receptor responses to stretch were decreased in high fat diet compared to standard laboratory diet TRPV1+/+ mice; an effect not observed in TRPV1-/- mice. Disruption of TRPV1 had no effect on the response of mucosal receptors to mucosal stroking in mice on either diet.TRPV1 channels selectively modulate gastric vagal afferent tension receptor mechanosensitivity and may mediate the reduction in gastric vagal afferent mechanosensitivity in high fat diet-induced obesity.

  19. Artificial Consciousness or Artificial Intelligence

    Directory of Open Access Journals (Sweden)

    Spanache Florin

    2017-05-01

    Full Text Available Artificial intelligence is a tool designed by people for the gratification of their own creative ego, so we can not confuse conscience with intelligence and not even intelligence in its human representation with conscience. They are all different concepts and they have different uses. Philosophically, there are differences between autonomous people and automatic artificial intelligence. This is the difference between intelligence and artificial intelligence, autonomous versus automatic. But conscience is above these differences because it is neither conditioned by the self-preservation of autonomy, because a conscience is something that you use to help your neighbor, nor automatic, because one’s conscience is tested by situations which are not similar or subject to routine. So, artificial intelligence is only in science-fiction literature similar to an autonomous conscience-endowed being. In real life, religion with its notions of redemption, sin, expiation, confession and communion will not have any meaning for a machine which cannot make a mistake on its own.

  20. PENGARUH DIET KACANG MERAH TERHADAP KADAR GULA DARAH TIKUS DIABETIK INDUKSI ALLOXAN [Effect of Red Bean Diet on Blood Glucose Concentration of Alloxan-Induced Diabetic Rats

    Directory of Open Access Journals (Sweden)

    Y. Marsono 1

    2003-04-01

    Full Text Available Hypoglycemic response of red bean were evaluated in alloxan-induced diabetic rats. The objective of this research was to evaluate the effect of red bean (Vigna umbellata diet compare with soy bean diet on blood glucose concentration in alloxan-induced diabetic rats.Thirty male Sprague-Dawley (SD rats (250-300 g were diabetic induced by alloxan injection (80 mg/kg of body weight by intra muscular injection. They were divided into three groups of ten rats. They were fed (1 Standard diet (STD, (2 Red bean diet (KM, and (3 Soy bean diet (KD for 28 days. Concentration of serum glucose were determined before injection (0 day,after injection (day 17th and every sweek during diet intervention (day 24,31,38 and 45thIt was found that alloxan injection increased serum glucose concentration of STD, KM, and KD rats. After 28 days intervention, red bean decreased the serum glucose concentration from 217, 87 mg/dL to 57,70 mg/dL (69 % in KM groups and from 218,94 mg/dL to 76,82 mg/dL (65 % in KD groups, but standard diet (STD were decreased less than both of KM and KD diet.

  1. Fad diets, miracle diets, diet cult… but no results.

    Directory of Open Access Journals (Sweden)

    Ignacio Jáuregui-Lobera

    2017-03-01

    Full Text Available Fad diets, miracle diets (in sum, diet cult are diets that make promises of weight loss or other health advantages (e.g. longer life without backing by solid science, and usually they are characterized by highly restrictive or unusual food choices. These diets are often supported by celebrities and some health “professionals”, and they result attractive among people who want to lose weight quickly. By means of pseudoscientific arguments, designers of fad, miracle or magic diets usually describe them as healthy diets with unusual properties but always with undoubted benefits. After revising the history of these diets and exploring the scientific evidence, it must be noted that there is not a diet better than eating less, moving more and eating lots of fruits and vegetables. In addition, it is necessary to be aware of our general daily habits, remembering that eating is important but it is not everything. Getting active is also very relevant to improve (or recover our health. Summarizing, eating healthy and taking care of yourself are a duty but not a miracle.

  2. The effectiveness of vegetable protein diet for refeeding malnourished children recovering from shigella

    International Nuclear Information System (INIS)

    Kabir, I.; Halliday, D.; Underwood, L.E.

    1996-01-01

    Shigellosis is a major cause of childhood mortality in developing countries. A substantial proportion of children who survive develop secondary protein-energy malnutrition (PEM) and become stunted. In a previous study at ICDDR, B using a high-protein (animal) diet with generous portions of selected micronutrients, we were able to show accelerated rates of catch-up in weight and length gain, i.e., to begin to reverse stunting. However, the dietary ingredients we used are costly and therefore the intervention is impractical. Therefore, the next step is to rest the hypothesis that stunting can also be reversed by carefully formulated diets based on affordable ingredients. To test this hypothesis, we will use rice-legum-based diets in which the amino acid patterns are complimentary, and will supplement the diet to increase intake of key micronutrients which affect linear growth. The effects of the experimental diet will be compared with those of a standard diet recommended by WHO/FAO and with those of the diet we used previously, which was based on animal products and provided 15% of energy as protein and more micronutrients than the standard refeeding diet. We will measure growth by standard means, but will add measurements of protein anabolism to learn whether this is an early predictor of length gain. 29 refs, 1 tab

  3. The effectiveness of vegetable protein diet for refeeding malnourished children recovering from shigella

    International Nuclear Information System (INIS)

    Kabir, I.; Halliday, D.; Underwood, L.E.

    1994-01-01

    Shigellosis is a major cause of childhood mortality in developing countries. A substantial proportion of children who survive develop secondary protein-energy malnutrition (PEM) and become stunted. In a previous study at ICDDR,B using a high-protein (animal) diet with generous portions of selected micronutrients, we were able to show accelerated rates of catch-up in weight and length gain, i.e., to begin to reverse stunting. However, the dietary ingredients we used are costly and therefore the intervention is impractical. Therefore, the next step is to test the hypothesis that stunting can also be reversed by carefully formulated diets based on affordable ingredients. To test this hypothesis, we will use rice-legume-based diets in which the amino acid patterns are complimentary, and will supplement the diet to increase intake of key micronutrients which affect linear growth. The effect of the experimental diet will be compared with those of a standard diet recommended by WHO/FAO and with those of the diet we used previously, which was based on animal products and provided 15% of energy as protein and more micronutrients than the standard refeeding diet. We will measure growth by standard means, but will add measurements of protein anabolism to learn whether this is an early predictor of length gain. 29 refs, 3 tabs

  4. The effectiveness of vegetable protein diet for refeeding malnourished children recovering from shigella

    Energy Technology Data Exchange (ETDEWEB)

    Kabir, I [International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDRB) (India); Halliday, D [Clinical Research Centre, Middlesex (United Kingdom); Underwood, L E [North Carolina Univ., Chapel Hill, NC (United States)

    1994-12-31

    Shigellosis is a major cause of childhood mortality in developing countries. A substantial proportion of children who survive develop secondary protein-energy malnutrition (PEM) and become stunted. In a previous study at ICDDR,B using a high-protein (animal) diet with generous portions of selected micronutrients, we were able to show accelerated rates of catch-up in weight and length gain, i.e., to begin to reverse stunting. However, the dietary ingredients we used are costly and therefore the intervention is impractical. Therefore, the next step is to test the hypothesis that stunting can also be reversed by carefully formulated diets based on affordable ingredients. To test this hypothesis, we will use rice-legume-based diets in which the amino acid patterns are complimentary, and will supplement the diet to increase intake of key micronutrients which affect linear growth. The effect of the experimental diet will be compared with those of a standard diet recommended by WHO/FAO and with those of the diet we used previously, which was based on animal products and provided 15% of energy as protein and more micronutrients than the standard refeeding diet. We will measure growth by standard means, but will add measurements of protein anabolism to learn whether this is an early predictor of length gain. 29 refs, 3 tabs.

  5. Diet-induced metabolic hamster model of nonalcoholic fatty liver disease

    Directory of Open Access Journals (Sweden)

    Bhathena J

    2011-06-01

    Full Text Available Jasmine Bhathena, Arun Kulamarva, Christopher Martoni, Aleksandra Malgorzata Urbanska, Meenakshi Malhotra, Arghya Paul, Satya PrakashBiomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Artificial Cells and Organs Research Centre, Faculty of Medicine, McGill University, Montreal, Québec, CanadaBackground: Obesity, hypercholesterolemia, elevated triglycerides, and type 2 diabetes are major risk factors for metabolic syndrome. Hamsters, unlike rats or mice, respond well to diet-induced obesity, increase body mass and adiposity on group housing, and increase food intake due to social confrontation-induced stress. They have a cardiovascular and hepatic system similar to that of humans, and can thus be a useful model for human pathophysiology.Methods: Experiments were planned to develop a diet-induced Bio F1B Golden Syrian hamster model of dyslipidemia and associated nonalcoholic fatty liver disease in the metabolic syndrome. Hamsters were fed a normal control diet, a high-fat/high-cholesterol diet, a high-fat/high-cholesterol/methionine-deficient/choline-devoid diet, and a high-fat/high-cholesterol/choline-deficient diet. Serum total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, glucose, atherogenic index, and body weight were quantified biweekly. Fat deposition in the liver was observed and assessed following lipid staining with hematoxylin and eosin and with oil red O.Results: In this study, we established a diet-induced Bio F1B Golden Syrian hamster model for studying dyslipidemia and associated nonalcoholic fatty liver disease in the metabolic syndrome. Hyperlipidemia and elevated serum glucose concentrations were induced using this diet. Atherogenic index was elevated, increasing the risk for a cardiovascular event. Histological analysis of liver specimens at the end of four weeks showed increased fat deposition in the liver of animals fed

  6. Comparison of Boolean analysis and standard phylogenetic methods using artificially evolved and natural mt-tRNA sequences from great apes.

    Science.gov (United States)

    Ari, Eszter; Ittzés, Péter; Podani, János; Thi, Quynh Chi Le; Jakó, Eena

    2012-04-01

    Boolean analysis (or BOOL-AN; Jakó et al., 2009. BOOL-AN: A method for comparative sequence analysis and phylogenetic reconstruction. Mol. Phylogenet. Evol. 52, 887-97.), a recently developed method for sequence comparison uses the Iterative Canonical Form of Boolean functions. It considers sequence information in a way entirely different from standard phylogenetic methods (i.e. Maximum Parsimony, Maximum-Likelihood, Neighbor-Joining, and Bayesian analysis). The performance and reliability of Boolean analysis were tested and compared with the standard phylogenetic methods, using artificially evolved - simulated - nucleotide sequences and the 22 mitochondrial tRNA genes of the great apes. At the outset, we assumed that the phylogeny of Hominidae is generally well established, and the guide tree of artificial sequence evolution can also be used as a benchmark. These offer a possibility to compare and test the performance of different phylogenetic methods. Trees were reconstructed by each method from 2500 simulated sequences and 22 mitochondrial tRNA sequences. We also introduced a special re-sampling method for Boolean analysis on permuted sequence sites, the P-BOOL-AN procedure. Considering the reliability values (branch support values of consensus trees and Robinson-Foulds distances) we used for simulated sequence trees produced by different phylogenetic methods, BOOL-AN appeared as the most reliable method. Although the mitochondrial tRNA sequences of great apes are relatively short (59-75 bases long) and the ratio of their constant characters is about 75%, BOOL-AN, P-BOOL-AN and the Bayesian approach produced the same tree-topology as the established phylogeny, while the outcomes of Maximum Parsimony, Maximum-Likelihood and Neighbor-Joining methods were equivocal. We conclude that Boolean analysis is a promising alternative to existing methods of sequence comparison for phylogenetic reconstruction and congruence analysis. Copyright © 2012 Elsevier Inc. All

  7. Artificial reefs and reef restoration in the Laurentian Great Lakes

    Science.gov (United States)

    McLean, Matthew W.; Roseman, Edward; Pritt, Jeremy J.; Kennedy, Gregory W.; Manny, Bruce A.

    2015-01-01

    We reviewed the published literature to provide an inventory of Laurentian Great Lakes artificial reef projects and their purposes. We also sought to characterize physical and biological monitoring for artificial reef projects in the Great Lakes and determine the success of artificial reefs in meeting project objectives. We found records of 6 artificial reefs in Lake Erie, 8 in Lake Michigan, 3 in Lakes Huron and Ontario, and 2 in Lake Superior. We found 9 reefs in Great Lakes connecting channels and 6 reefs in Great Lakes tributaries. Objectives of artificial reef creation have included reducing impacts of currents and waves, providing safe harbors, improving sport-fishing opportunities, and enhancing/restoring fish spawning habitats. Most reefs in the lakes themselves were incidental (not created purposely for fish habitat) or built to improve local sport fishing, whereas reefs in tributaries and connecting channels were more frequently built to benefit fish spawning. Levels of assessment of reef performance varied; but long-term monitoring was uncommon as was assessment of physical attributes. Artificial reefs were often successful at attracting recreational species and spawning fish; however, population-level benefits of artificial reefs are unclear. Stressors such as sedimentation and bio-fouling can limit the effectiveness of artificial reefs as spawning enhancement tools. Our investigation underscores the need to develop standard protocols for monitoring the biological and physical attributes of artificial structures. Further, long-term monitoring is needed to assess the benefits of artificial reefs to fish populations and inform future artificial reef projects.

  8. Carcass analysis to improve a meat-based diet for the artificial rearing of the predatory mirid bug Dicyphus tamaninii.

    Science.gov (United States)

    Zapata, Rafael; Specty, Olivier; Grenier, Simon; Febvay, Gérard; Pageaux, Jean François; Delobel, Bernard; Castañé, Cristina

    2005-10-01

    Improvement of an existing meat-based diet has been obtained for rearing the generalist predator Dicyphus tamaninii (Heteroptera: Miridae). The approach followed, different from the classical addition/deletion method, was performing biochemical analysis of adult carcasses in order to have information about the nutritional status of the predator. Comparison of total, free amino acids and lipid composition of meat-reared and conventionally reared females allowed detecting some nutritional deficiencies. A reformulated diet with new sources of proteins and lipids was tested again with the predator. Some biological parameters of bugs that were inferior in the initial meat diet when compared with those of the conventionally reared insects, such as nymphal development time and fresh weight, have been improved with the reformulated diet. (c) 2005 Wiley-Liss, Inc.

  9. Is it nutrients, food items, diet quality or eating behaviours that are responsible for the association of children's diet with sleep?

    Science.gov (United States)

    Khan, Mohammad K A; Faught, Erin L; Chu, Yen Li; Ekwaru, John P; Storey, Kate E; Veugelers, Paul J

    2017-08-01

    Both diet quality and sleep duration of children have declined in the past decades. Several studies have suggested that diet and sleep are associated; however, it is not established which aspects of the diet are responsible for this association. Is it nutrients, food items, diet quality or eating behaviours? We surveyed 2261 grade 5 children on their dietary intake and eating behaviours, and their parents on their sleep duration and sleep quality. We performed factor analysis to identify and quantify the essential factors among 57 nutrients, 132 food items and 19 eating behaviours. We considered these essential factors along with a diet quality score in multivariate regression analyses to assess their independent associations with sleep. Nutrients, food items and diet quality did not exhibit independent associations with sleep, whereas two groupings of eating behaviours did. 'Unhealthy eating habits and environments' was independently associated with sleep. For each standard deviation increase in their factor score, children had 6 min less sleep and were 12% less likely to have sleep of good quality. 'Snacking between meals and after supper' was independently associated with sleep quality. For each standard deviation increase in its factor score, children were 7% less likely to have good quality sleep. This study demonstrates that eating behaviours are responsible for the associations of diet with sleep among children. Health promotion programmes aiming to improve sleep should therefore focus on discouraging eating behaviours such as eating alone or in front of the TV, and snacking between meals and after supper. © 2016 European Sleep Research Society.

  10. Results Assessment of Intercomparison Exercise CSN/CIEMAT-2010 among Spanish National Laboratories of Environmental Radioactivity (Diet Ashes); Evaluacion de la Intercomparacion CSN/CIEMAT-2010 entre los Laboratorios Nacionales de Radiactividad Ambiental (Ceniza de Dieta)

    Energy Technology Data Exchange (ETDEWEB)

    Gasco, C.; Trinidad, J. A.; Llaurado, M.; Suarez, J. A.

    2012-06-08

    This report describes the results assessment of the intercomparison exercise among environmental radioactivity laboratories, organised by Spanish Regulatory Institution (CSN) and prepared and evaluated by UAB and CIEMAT respectively. The exercise has been carried out following the international standards ISO-43 and ISO/IUPAC that provide a useful guide to perform proficiency tests and inter-laboratories comparisons. The selected matrix for this year (2010) was a diet ash obtained from the ashing of a whole fresh diet (breakfast, lunch and dinner), that was enriched with artificial radionuclides (Cs-137, Co-60,Fe-55,Ni-63,Sr-90,Am-241,Pu-238,Pu-239,240 y C-14) and contained natural radionuclides (U-234, U-238, U-natural Th-230, Th-234, Ra-226, Ra-228, Pb-210, Pb-212, Pb-214, Bi-214, Ac-228, Tl-208, K-40) at environmental level of activity concentration. The z-score test was applied to determine how much the laboratories differ from the reference value. The reference value for this exercise was the median of the results from the different laboratories and their standard deviations to achieve a more complete and objective study of the laboratories performance. The participant laboratories have demonstrated a satisfactory quality level for measuring the natural and artificial radionuclides content in this matrix. The reference values obtained through the medians show a negative bias for Pb-210 and Th-234 when comparing to the given values of external qualified laboratories from ENEA and IRSN and positive one for K-40. (Author)

  11. Development and reproductive potential of Tyrophagus putrescentiae (Acari: Acaridae) on plant-parasitic nematodes and artificial diets.

    Science.gov (United States)

    Abou El-Atta, Doaa Abd El-Maksoud; Osman, Mohamed Ali

    2016-04-01

    This study investigated development, reproduction and life table parameters of the astigmatid mold mite Tyrophagus putrescentiae (Schrank) (Acari: Acaridae) feeding on egg-masses or adult females of the nematode Meloidogyne incognita, egg-masses of the nematode Rotylenchulus reniformis, ras cheese or yeast at 25 ± 1 °C, 70 ± 10 % RH in the dark. Immature developmental times were shorter when the mite was fed females of M. incognita followed by yeast. Different prey/diet types had no significant effect on longevity and lifespan of both males and females. Daily oviposition rate (eggs/female/day) was highest for mites fed yeast (20.8 ± 1.8 eggs) and lowest for mites fed females of M. incognita (6.6 ± 0.5). Intrinsic rate of natural increase (r m) was highest for mites fed yeast compared to other prey/diet; no significant differences in r m were observed among mites fed on non-yeast diets. This result may suggest a role of T. putrescentiae as biocontrol agent of plant-parasitic nematodes and the yeast may be used for mite mass-production purposes.

  12. Desenvolvimento pós-embrionário de Pattonella intermutans (Thomson (Diptera: Sarcophagidae em diferentes dietas Post-embryonary development of Pattonella intermutans (Thomson, 1869 in different diets

    Directory of Open Access Journals (Sweden)

    Marcio S. Loureiro

    2005-03-01

    Full Text Available A proposta deste estudo foi de avaliar o desenvolvimento pós-embrionário de Pattonella intermutans (Thomson, 1869 em dietas artificiais preparadas com agar-agar. Dieta D1: leite em pó integral + fermento biológico; Dieta D2: leite em pó integral + fermento biológico + caseína; Dieta D3: leite em pó integral + ovo cru; Dieta D4: carne bovina moída (dieta controle. A carne bovina moída foi a dieta mais eficiente (peso larval de 195,63 mg e viabilidade de neolarva a adulto de 86,5%, quando comparada com as dietas artificiais. Os seguintes resultados foram obtidos para o grupo experimental: Dieta D3: 180,15 mg e 63,5%; Dieta D2: 141,07 mg e 61% e na Dieta D1: 147,98 mg e 51,5%.The purpose of this study was to evaluate the post-embryonary development of Pattonella intermutans (Thomson, 1969 in artificial diets composed of agar-agar. Diet D1: whole dried milk + dried brewer's yeast; Diet D2: whole dried milk + dried brewer's yeast+ casein; Diet D3: whole dried milk + whole egg; Diet D4: bovine meal (control diet. The bovine meat was the best diet (larval weight 195.63mg and viability from larvae to adult 86,5%, when compared to all other artificial diets. The following performances were obtained for experimental groups: diet D3: 180.15 mg and 63.5%; diet D2: 141.07 mg and 61% and diet D1: 147.98 mg e 51.5%.

  13. Effects of diet on resource utilization by a model human gut microbiota containing Bacteroides cellulosilyticus WH2, a symbiont with an extensive glycobiome.

    Directory of Open Access Journals (Sweden)

    Nathan P McNulty

    Full Text Available The human gut microbiota is an important metabolic organ, yet little is known about how its individual species interact, establish dominant positions, and respond to changes in environmental factors such as diet. In this study, gnotobiotic mice were colonized with an artificial microbiota comprising 12 sequenced human gut bacterial species and fed oscillating diets of disparate composition. Rapid, reproducible, and reversible changes in the structure of this assemblage were observed. Time-series microbial RNA-Seq analyses revealed staggered functional responses to diet shifts throughout the assemblage that were heavily focused on carbohydrate and amino acid metabolism. High-resolution shotgun metaproteomics confirmed many of these responses at a protein level. One member, Bacteroides cellulosilyticus WH2, proved exceptionally fit regardless of diet. Its genome encoded more carbohydrate active enzymes than any previously sequenced member of the Bacteroidetes. Transcriptional profiling indicated that B. cellulosilyticus WH2 is an adaptive forager that tailors its versatile carbohydrate utilization strategy to available dietary polysaccharides, with a strong emphasis on plant-derived xylans abundant in dietary staples like cereal grains. Two highly expressed, diet-specific polysaccharide utilization loci (PULs in B. cellulosilyticus WH2 were identified, one with characteristics of xylan utilization systems. Introduction of a B. cellulosilyticus WH2 library comprising >90,000 isogenic transposon mutants into gnotobiotic mice, along with the other artificial community members, confirmed that these loci represent critical diet-specific fitness determinants. Carbohydrates that trigger dramatic increases in expression of these two loci and many of the organism's 111 other predicted PULs were identified by RNA-Seq during in vitro growth on 31 distinct carbohydrate substrates, allowing us to better interpret in vivo RNA-Seq and proteomics data. These

  14. Breast Cancer Diagnosis using Artificial Neural Networks with Extreme Learning Techniques

    OpenAIRE

    Chandra Prasetyo Utomo; Aan Kardiana; Rika Yuliwulandari

    2014-01-01

    Breast cancer is the second cause of dead among women. Early detection followed by appropriate cancer treatment can reduce the deadly risk. Medical professionals can make mistakes while identifying a disease. The help of technology such as data mining and machine learning can substantially improve the diagnosis accuracy. Artificial Neural Networks (ANN) has been widely used in intelligent breast cancer diagnosis. However, the standard Gradient-Based Back Propagation Artificial Neural Networks...

  15. Biofortified red mottled beans (Phaseolus vulgaris L. in a maize and bean diet provide more bioavailable iron than standard red mottled beans: Studies in poultry (Gallus gallus and an in vitro digestion/Caco-2 model

    Directory of Open Access Journals (Sweden)

    Glahn Raymond P

    2011-10-01

    Full Text Available Abstract Background Our objective was to compare the capacities of biofortified and standard colored beans to deliver iron (Fe for hemoglobin synthesis. Two isolines of large-seeded, red mottled Andean beans (Phaseolus vulgaris L., one standard ("Low Fe" and the other biofortified ("High Fe" in Fe (49 and 71 μg Fe/g, respectively were used. This commercial class of red mottled beans is the preferred varietal type for most of the Caribbean and Eastern and Southern Africa where almost three quarters of a million hectares are grown. Therefore it is important to know the affect of biofortification of these beans on diets that simulate human feeding studies. Methods Maize-based diets containing the beans were formulated to meet the nutrient requirements for broiler except for Fe (Fe concentrations in the 2 diets were 42.9 ± 1.2 and 54.6 ± 0.9 mg/kg. One day old chicks (Gallus gallus were allocated to the experimental diets (n = 12. For 4 wk, hemoglobin, feed-consumption and body-weights were measured. Results Hemoglobin maintenance efficiencies (HME (means ± SEM were different between groups on days 14 and 21 of the experiment (P In-vitro analysis showed lower iron bioavailability in cells exposed to standard ("Low Fe" bean based diet. Conclusions We conclude that the in-vivo results support the in-vitro observations; biofortified colored beans contain more bioavailable-iron than standard colored beans. In addition, biofortified beans seems to be a promising vehicle for increasing intakes of bioavailable Fe in human populations that consume these beans as a dietary staple. This justifies further work on the large-seeded Andean beans which are the staple of a large-region of Africa where iron-deficiency anemia is a primary cause of infant death and poor health status.

  16. Fate and behaviour of phenanthrene in the natural and artificial soils

    International Nuclear Information System (INIS)

    Hofman, Jakub; Rhodes, Angela; Semple, Kirk T.

    2008-01-01

    OECD artificial soil has been used routinely as a standardized substrate for soil toxicity tests. However, can be the fate, behaviour and effects of contaminants in artificial soil extrapolated to natural soils? The aim of our study was to verify this hypothesis by comparing the loss, extraction, and bioavailability of phenanthrene in three artificial and three natural soils of comparable organic carbon content. Soils were spiked with 14 C-phenanthrene and total 14 C-activity change, the fractions extracted by dichloromethane, 70% ethanol, and hydroxypropyl-β-cyclodextrin, the fraction mineralized by Pseudomonas sp., and taken up by Enchytraeus albidus were measured after 1, 14, 42, and 84 d aging. The loss, extraction, biodegradation and uptake were several times lower in the artificial than natural soils and these differences increased with increasing soil-phenanthrene contact time. These results imply that artificial soil should be used cautiously for the prediction of fate and behaviour in natural soils. - Artificial soils show substantially different fate and behaviour of phenanthrene than natural soils, which cannot be easily extrapolated or modelled

  17. Effects of high-impact exercise on the physical properties of bones of ovariectomized rats fed to a high-protein diet.

    Science.gov (United States)

    Shimano, R C; Yanagihara, G R; Macedo, A P; Yamanaka, J S; Shimano, A C; Tavares, J M R S; Issa, J P M

    2018-05-01

    The aim of this study was to evaluate the effects of high-impact physical exercise as a prophylactic and therapeutic means in osteopenic bones of rats submitted to ovariectomy and protein diet intake. A total of 64 Wistar rats were divided into eight groups (n = 8 each), being: OVX, ovx, standard diet and sedentary; OVXE, ovx, standard diet and jump; OVXP, ovx, high-protein diet and sedentary; and OVXEP, ovx, high-protein diet and jump; SH, sham, standard diet and sedentary; SHE, sham, standard diet and jump; SHP, sham, high-protein diet and sedentary; and SHEP, sham, high-protein diet and jump. OVX surgery consists of ovariectomy, and sham was the control surgery. The jumping protocol consisted of 20 jumps/day, 5 days/week. The bone structure was evaluated by densitometry, mechanical tests, histomorphometric, and immunohistochemical analyses. A high-protein diet resulted in increased bone mineral density (P = .049), but decreased maximal load (P = .026) and bone volume fraction (P = .023). The benefits of physical exercise were demonstrated by higher values of the maximal load in the trained groups compared to the sedentary groups (P high-protein diet (P = .005) and jump exercise (P = .017) resulted in lower immunostaining of osteopontin compared to the standard diet and sedentary groups, respectively. In this experimental model, it was concluded that ovariectomy and a high-fat diet can negatively affect bone tissue and the high-impact exercise was not enough to suppress the deleterious effects caused by the protein diet and ovariectomy. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Poliuretana derivada de óleos vegetais exposta ao intemperismo artificial Polyurethane derived from vegetal oil exposed to artificial weathering

    Directory of Open Access Journals (Sweden)

    Alessandra E. F. S. Almeida

    2006-01-01

    Full Text Available Foram obtidas as propriedades mecânicas e viscoelásticas da poliuretana derivada do óleo de mamona após sua exposição ao intemperismo artificial, a fim de avaliar a aplicabilidade deste material como revestimento polimérico para substratos de concreto na Construção Civil. Os procedimentos experimentais foram realizados em conformidade com a ASTM G 53 for "Operating Light and Water Exposure Apparatus (Fluorescent UV - Condensation Type for Exposure of Nonmetallic Materials"[1]. O ensaio para a caracterização mecânica dos corpos-de-prova após exposição ao intemperismo artificial foi realizado conforme a norma ASTM D 638M-96 "Standard Test Method for Tensile Properties of Plastics (Metric"[2]. Foi empregado o método de análise dinâmico-mecânica para a obtenção das propriedades viscoelásticas da poliuretana vegetal. Os resultados mostraram que a exposição ao intemperismo artificial não ocasionou mudanças significativas nas propriedades do revestimento polimérico para o tempo de exposição estudado.The mechanical and viscoelastic properties of polyurethane derived from castor oil were obtained after being exposed to artificial weathering with the purpose of evaluating their applicability as polymeric coatings on concrete substrate for Civil Construction. The procedures followed the ASTM G53 for "Operating Light and Water Exposure Apparatus (Fluorescent UV - Condensation Type for Exposure of Nonmetallic Materials"[1]. Mechanical properties were obtained by means of the ASTM D 638M-96 "Standard Test Method for Tensile Properties of Plastics (Metric"[2]. Furthermore, a Dynamic Mechanical Analysis (DMA was carried out in order to study the viscoelastic properties of polyurethane. The results showed that the properties were altered slightly considering the time studied.

  19. Elite football on artificial turf versus natural grass: Movement patterns, technical standards, and player impressions

    DEFF Research Database (Denmark)

    Andersson, Helena; Ekblom, Björn; Krustrup, Peter

    2008-01-01

    The aim of the present study was to examine the movement patterns, ball skills, and the impressions of Swedish elite football players during competitive games on artificial turf and natural grass. Time - motion analyses (36 observations) and technical analyses (16 team observations) were performed...... and 72 male and 21 female players completed a questionnaire. No differences were observed between artificial turf and natural grass in terms of total distance covered (mean 10.19 km, s = 0.19 vs. 10.33 km, s = 0.23), high-intensity running (1.86 km, s = 0.10 vs. 1.87 km, s = 0.14), number of sprints (21...

  20. [Clinical application of artificial condylar process for reconstructing temporomandibular joint].

    Science.gov (United States)

    Huang, Xiangdao; Shao, Zhanying; Wang, Fasheng; Duan, Yi

    2012-01-01

    To assess the feasibility and clinical outcomes of artificial condylar process in reconstruction of the temporomandibular joint. Between January 2005 and January 2010, the reconstructions of the temporomandibular joints with artificial condylar process were performed in 10 cases (11 sides, including 7 left sides and 4 right sides). There were 7 males and 3 females with an average age of 50 years (range, 40-68 years). Mandibular condyle defects were caused by mandible tumor in 7 patients with a mean disease duration of 15 months (range, 9-24 months) and by bilateral condylar fractures in 3 patients with the disease duration of 2, 3, and 2 days respectively. According to Neff classification, there were type M and A in 1 case, type M and B in 1 case, and type M in one side and subcondylar fracture in the other side in 1 case. Incisions in all patients healed by first intention, and no complication occurred. All cases were followed up 1 to 4 years, showed facial symmetry and good occluding relation, and the mouth opening was 22-38 mm (mean, 30 mm). No temporomandibular joint clicking or pain and no recurrence of tumor were observed. Most of the artificial condylar process were in good position except 1 deviated from the correct angle slightly. All the patients could have diet normally. The results of temporomandibular joint reconstruction after tumor resection with artificial condylar process are good, but the clinical outcome for intracapsular condylar fracture is expected to be further verified.

  1. Biochemical attributes of Hens Fed Irradiated Aflatoxin B1 Contamination Diet

    International Nuclear Information System (INIS)

    Farag, M.D.E.H.; Abdul Azeem, A.M.; Abdalla, E.A.; Ahmed, N.A.H.

    2017-01-01

    The purpose of this study is to evaluate the effect of feeding diet artificially contaminated with aflatoxin B 1(AFB1) at level 0.2 mg kg"-"1 AFB1, and gamma (γ) irradiated (10, 20, and 30 kGy) on reducing the deleterious effects of laying hens Golden Montaza (GM) biochemical attributes. These include liver weight, AFB1 liver residue content, AST, ALT, ALP, creatinine, total proteins, albumin and globulin, as well as, the levels of T3, T4, TSH, FSH, LH, progesterone hormone and hepatic histology. At 38 week of age, groups of laying hens were fed on a normal non-contaminated diet (G1), aflatoxin-contaminated diet (G2), and irradiated contaminated diets (G3, G4 and G5) for 3 weeks, as a duration period. When the hens reached 42 weeks of age, they were fed on normal diet for 3 weeks, as a recovery period. Results showed that AST, ALT, ALP, and creatinine significantly increased in AFs treated groups in comparison with those received AFs-containing diet and irradiated up to 30 kGy. Layers fed contaminated diet of AFB1 suffered from a lower level of total proteins, albumin and globulin. Meanwhile, the results showed that the level of serum T4 was lower, but conversely the levels of FSH were higher for those fed on diets contaminated with AFB1 compared to those fed irradiated contaminated diets with AFB1, no significant change occurred in serum blood T3, TSH, LH and progesterone in all tested groups. Treated contaminated diets with γ-irradiation at 30 kGy reduced the incidence and severity of hepatic histology. The 30 kGy radiation dose was more effective, in this respect, in all biochemical indices. For recovery period diets non-contaminated with AFB1, the results showed improvements in all biochemical indices and recovered the hepatic structure with increasing the recovery period especially for those fed on irradiated diets through the experimental duration. In conclusion, feeding of diets contaminated with AFB1 altered the blood profiles, and damaged the liver

  2. Efficiency of two larval diets for mass-rearing of the mosquito Aedes aegypti.

    Directory of Open Access Journals (Sweden)

    J G Bond

    Full Text Available Aedes aegypti is a major vector of arboviruses that may be controlled on an area-wide basis using the sterile insect technique (SIT. Larval diet is a major factor in mass-rearing for SIT programs. We compared dietary effects on immature development and adult fitness-related characteristics for an International Atomic Energy Agency (IAEA diet, developed for rearing Ae. albopictus, and a standardized laboratory rodent diet (LRD, under a 14:10 h (light:dark photoperiod ("light" treatment or continuous darkness during larval rearing. Larval development was generally fastest in the IAEA diet, likely reflecting the high protein and lipid content of this diet. The proportion of larvae that survived to pupation or to adult emergence did not differ significantly between diets or light treatments. Insects from the LRD-dark treatment produced the highest proportion of male pupae (93% at 24 h after the beginning of pupation whereas adult sex ratio from the IAEA diet tended to be more male-biased than that of the LRD diet. Adult longevity did not differ significantly with larval diet or light conditions, irrespective of sex. In other aspects the LRD diet generally performed best. Adult males from the LRD diet were significantly larger than those from the IAEA diet, irrespective of light treatment. Females from the LRD diet had ~25% higher fecundity and ~8% higher egg fertility compared to those from the IAEA diet. Adult flight ability did not differ between larval diets, and males had a similar number of copulations with wild females, irrespective of larval diet. The LRD diet had lower protein and fat content but a higher carbohydrate and energetic content than the IAEA diet. We conclude that the LRD diet is a low-cost standardized diet that is likely to be suitable for mass-rearing of Ae. aegypti for area-wide SIT-based vector control.

  3. Artificial skin and patient simulator comprising the artificial skin

    NARCIS (Netherlands)

    2011-01-01

    The invention relates to an artificial skin (10, 12, 14), and relates to a patient simulator (100) comprising the artificial skin. The artificial skin is a layered structure comprising a translucent cover layer (20) configured for imitating human or animal skin, and comprising a light emitting layer

  4. Simulation of Blood flow in Artificial Heart Valve Design through Left heart

    Science.gov (United States)

    Hafizah Mokhtar, N.; Abas, Aizat

    2018-05-01

    In this work, an artificial heart valve is designed for use in real heart with further consideration on the effect of thrombosis, vorticity, and stress. The design of artificial heart valve model is constructed by Computer-aided design (CAD) modelling and simulated using Computational fluid dynamic (CFD) software. The effect of blood flow pattern, velocity and vorticity of the artificial heart valve design has been analysed in this research work. Based on the results, the artificial heart valve design shows that it has a Doppler velocity index that is less than the allowable standards for the left heart with values of more than 0.30 and less than 2.2. These values are safe to be used as replacement of the human heart valve.

  5. Artificial Neural Networks and the Mass Appraisal of Real Estate

    Directory of Open Access Journals (Sweden)

    Gang Zhou

    2018-03-01

    Full Text Available With the rapid development of computer, artificial intelligence and big data technology, artificial neural networks have become one of the most powerful machine learning algorithms. In the practice, most of the applications of artificial neural networks use back propagation neural network and its variation. Besides the back propagation neural network, various neural networks have been developing in order to improve the performance of standard models. Though neural networks are well known method in the research of real estate, there is enormous space for future research in order to enhance their function. Some scholars combine genetic algorithm, geospatial information, support vector machine model, particle swarm optimization with artificial neural networks to appraise the real estate, which is helpful for the existing appraisal technology. The mass appraisal of real estate in this paper includes the real estate valuation in the transaction and the tax base valuation in the real estate holding. In this study we focus on the theoretical development of artificial neural networks and mass appraisal of real estate, artificial neural networks model evolution and algorithm improvement, artificial neural networks practice and application, and review the existing literature about artificial neural networks and mass appraisal of real estate. Finally, we provide some suggestions for the mass appraisal of China's real estate.

  6. Artificial Intelligence.

    Science.gov (United States)

    Information Technology Quarterly, 1985

    1985-01-01

    This issue of "Information Technology Quarterly" is devoted to the theme of "Artificial Intelligence." It contains two major articles: (1) Artificial Intelligence and Law" (D. Peter O'Neill and George D. Wood); (2) "Artificial Intelligence: A Long and Winding Road" (John J. Simon, Jr.). In addition, it contains two sidebars: (1) "Calculating and…

  7. Artificial organs: recent progress in artificial hearing and vision.

    Science.gov (United States)

    Ifukube, Tohru

    2009-01-01

    Artificial sensory organs are a prosthetic means of sending visual or auditory information to the brain by electrical stimulation of the optic or auditory nerves to assist visually impaired or hearing-impaired people. However, clinical application of artificial sensory organs, except for cochlear implants, is still a trial-and-error process. This is because how and where the information transmitted to the brain is processed is still unknown, and also because changes in brain function (plasticity) remain unknown, even though brain plasticity plays an important role in meaningful interpretation of new sensory stimuli. This article discusses some basic unresolved issues and potential solutions in the development of artificial sensory organs such as cochlear implants, brainstem implants, artificial vision, and artificial retinas.

  8. The Effects of a Low-Carbohydrate Diet vs. a Low-Fat Diet on Novel Cardiovascular Risk Factors: A Randomized Controlled Trial.

    Science.gov (United States)

    Hu, Tian; Yao, Lu; Reynolds, Kristi; Whelton, Paul K; Niu, Tianhua; Li, Shengxu; He, Jiang; Bazzano, Lydia A

    2015-09-17

    Increasing evidence supports a low-carbohydrate diet for weight loss and improvement in traditional cardiovascular disease (CVD) markers. Effects on novel CVD markers remain unclear. We examined the effects of a low-carbohydrate diet (low-fat diet (fat, fat; n = 73) on biomarkers representing inflammation, adipocyte dysfunction, and endothelial dysfunction in a 12 month clinical trial among 148 obese adults free of diabetes and CVD. Participants met with a study dietitian on a periodic basis and each diet group received the same behavioral curriculum which included dietary instruction and supportive counseling. Eighty percent of participants completed the intervention. At 12 months, participants on the low-carbohydrate diet had significantly greater increases in adiponectin (mean difference in change, 1336 ng/mL (95% CI, 342 to 2330 ng/mL); p = 0.009) and greater decreases in intercellular adhesion molecule-1 concentrations (-16.8 ng/mL (-32.0 to -1.6 ng/mL); p = 0.031) than those on the low-fat diet. Changes in other novel CVD markers were not significantly different between groups. In conclusion, despite the differences in weight changes on diets, a low-carbohydrate diet resulted in similar or greater improvement in inflammation, adipocyte dysfunction, and endothelial dysfunction than a standard low-fat diet among obese persons.

  9. Effects of liquid versus solid diet on colonic transit in humans. Evaluation by standard colonic transit scintigraphy

    International Nuclear Information System (INIS)

    Kaufman, P.N.; Richter, J.E.; Chilton, H.M.; Kerr, R.M.; Cowan, R.C.; Gelfand, D.W.; Ott, D.J.

    1990-01-01

    The effects of liquid versus solid diet on human colonic transit were investigated, and transit following cecal instillation of tracer was compared with transit following instillation in the proximal jejunum. In a randomized cross-over, single-blind fashion, 6 normal volunteers ingesting either normal solid foods or a liquid diet were studied using colonic transit scintigraphy. 111In-DTPA was instilled either into the cecum via a long intestinal tube or into the proximal jejunum via a feeding tube. Compared with the liquid diet, the solid diet slowed transit in the cecum and ascending colon (p less than 0.025) and delayed progression of the geometric center (p less than 0.05) during the first 4 h of the study. Transit from 18 to 48 h was similar on the 2 diets. On the solid diet, transit was similar whether 111In-DTPA was instilled into the proximal jejunum or into the cecum. Transit from the terminal ileum to the cecum was assessed in an additional 5 volunteers following jejunal instillation of 99mTc-DTPA. Cecal filling was rapid (T1/2 = 0.49 h) and complete in all subjects before the onset of cecal emptying. These results suggest that colonic transit is slower on a solid than a liquid diet and that jejunal instillation of radiopharmaceuticals should be suitable for colonic transit studies in most subjects

  10. Palatability of two artificial feeds for reindeer

    Directory of Open Access Journals (Sweden)

    Arne Rognmo

    1990-09-01

    Full Text Available Two groups of 15 reindeer were used to test the palatability of two artificial diets. None of the animals had experienced the diets before. Trials were carried out from April to mid May. Each group of animals was kept in a separate corral (600 sq. meters. Both groups were fed lichens for three days befort trials began. Then they were offered a concentrate feed (RF-80 or «Mill Waste Product» (MWP ad libitum. Both groups ate little or nothing for the first three days of the trial and so lichens were mixed with the two experimental feeds. The mean voluntary food intake of the RF-80-group increased from 0.8 Kg/day/animal to 1.8 Kg/day/animal after three weeks. A mixed feed, RF-80/lichen, was only used the first day for animals in the RF-80 group. Reindeer refused to eat MWP for twelve days despite mixing it with lichens. They were then offered RF-80 ad lib. without a mixture of lichens. The mean voluntary intake of these animals increased from 1.3 Kg RF-80/day/animal on day 13 to 2.3 Kg/day/animal by day 26. Two calves in the MWP-group got diarrhoea after refeeding with RF-80.

  11. The effects of probiotic, prebiotic and synbiotic diets containing Bacillus coagulans and inulin on rat intestinal microbiota.

    Science.gov (United States)

    Abhari, Kh; Shekarforoush, S S; Sajedianfard, J; Hosseinzadeh, S; Nazifi, S

    2015-01-01

    An in vivo experiment was conducted to study the effects of probiotic Bacillus coagulans spores, with and without prebiotic, inulin, on gastrointestinal (GI) microbiota of healthy rats and its potentiality to survive in the GI tract. Forty-eight male Wistar rats were randomly divided into four groups (n=12) and fed as follows: standard diet (control), standard diet supplied with 5% w/w long chain inulin (prebiotic), standard diet with 10(9)/day spores of B. coagulans by orogastric gavage (probiotic), and standard diet with 5% w/w long chain inulin and 10(9) spores/day of B. coagulans by orogastric gavage (synbiotic). Rats were fed the diets for 30 days. At day 10, 20 and 30 of experiment, 24 h post administration, four rats from each group were randomly selected and after faecal collection were sacrificed. Small intestine, cecum, and colon were excised from each rat and used for microbial analysis. Administration of synbiotic and probiotic diets led to a significant (Pcoagulans was efficient in beneficially modulating GI microbiota and considering transitional characteristics of B. coagulans, daily consumption of probiotic products is necessary for any long-term effect.

  12. An artificial intelligence framework for compensating transgressions and its application to diet management.

    Science.gov (United States)

    Anselma, Luca; Mazzei, Alessandro; De Michieli, Franco

    2017-04-01

    Today, there is considerable interest in personal healthcare. The pervasiveness of technology allows to precisely track human behavior; however, when dealing with the development of an intelligent assistant exploiting data acquired through such technologies, a critical issue has to be taken into account; namely, that of supporting the user in the event of any transgression with respect to the optimal behavior. In this paper we present a reasoning framework based on Simple Temporal Problems that can be applied to a general class of problems, which we called cake&carrot problems, to support reasoning in presence of human transgression. The reasoning framework offers a number of facilities to ensure a smart management of possible "wrong behaviors" by a user to reach the goals defined by the problem. This paper describes the framework by means of the prototypical use case of diet domain. Indeed, following a healthy diet can be a difficult task for both practical and psychological reasons and dietary transgressions are hard to avoid. Therefore, the framework is tolerant to dietary transgressions and adapts the following meals to facilitate users in recovering from such transgressions. Finally, through a simulation involving a real hospital menu, we show that the framework can effectively achieve good results in a realistic scenario. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. The Japanese diet from 1975 delays senescence and prolongs life span in SAMP8 mice.

    Science.gov (United States)

    Yamamoto, Kazushi; E, Shuang; Hatakeyama, Yu; Sakamoto, Yu; Honma, Taro; Jibu, Yuri; Kawakami, Yuki; Tsuduki, Tsuyoshi

    2016-01-01

    Life expectancy in Japan is high, suggesting that the Japanese diet, Nihon shoku (Japanese food), has significant health benefits. However, these benefits have been called into question over the past 50 y, during which time the Japanese diet has become increasingly Westernized. The aim of the present study was to focus on senescence delay and to examine the effects of Japanese diets from different years to identify which Japanese diet is most effective in enhancing life expectancy and delaying senescence. Weekly menus from the years 1960, 1975, 1990, and 2005 were reproduced based on the National Health and Nutrition Survey in Japan and prepared as powdered foods. The senescence-accelerated mouse prone 8 (SAMP8) mice were fed standard laboratory chow supplemented with a 30% mix of Japanese meals from various years ad libitum throughout their lifetime. Additionally, the control group was given standard laboratory chow only, to examine the development of mice reared under standard conditions. In the group that ingested the traditional 1975 Japanese diet, life span was prolonged, senescence was delayed, and learning and memory capacities were maintained compared with the group fed the 2005 Japanese diet. The life span of the group that ingested the 1990 Japanese diet showed a tendency to be longer than SAMP8 mice fed the 2005 diet. The results of the present study suggested that the traditional Japanese diet is more effective in enhancing life expectancy and delaying senescence than the current Japanese diet. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Artificial neural networks in variable process control: application in particleboard manufacture

    Energy Technology Data Exchange (ETDEWEB)

    Esteban, L. G.; Garcia Fernandez, F.; Palacios, P. de; Conde, M.

    2009-07-01

    Artificial neural networks are an efficient tool for modelling production control processes using data from the actual production as well as simulated or design of experiments data. In this study two artificial neural networks were combined with the control process charts and it was checked whether the data obtained by the networks were valid for variable process control in particleboard manufacture. The networks made it possible to obtain the mean and standard deviation of the internal bond strength of the particleboard within acceptable margins using known data of thickness, density, moisture content, swelling and absorption. The networks obtained met the acceptance criteria for test values from non-standard test methods, as well as the criteria for using these values in statistical process control. (Author) 47 refs.

  15. The effect of a low-glycemic diet vs a standard diet on blood glucose levels and macronutrient intake in children with type 1 diabetes.

    Science.gov (United States)

    Rovner, Alisha J; Nansel, Tonja R; Gellar, Lauren

    2009-02-01

    A low-glycemic index (GI) diet may lower postprandial hyperglycemia and decrease the risk for postabsorptive hypoglycemia in people with type 1 diabetes. However, insufficient evidence exists on the efficacy of a low-GI diet to support practice recommendations. The goal of this study was to examine the blood glucose response to and the macronutrient composition of low-GI meals vs usual meals consumed ad libitum at home in children with type 1 diabetes. A within-subject, crossover design was employed. Twenty-three participants were recruited between June and August 2006. Participants wore a continuous blood glucose monitoring system and completed diet diaries on 2 days. On 1 day, participants consumed their usual meal; on another day, participants consumed low-GI meals ad libidum. Order of the 2 days was counterbalanced. The mean GI was 34+/-6 for the low-GI day and 57+/-6 for the usual meal day (Plow-GI day, mean daytime blood glucose values (125+/-28 mg/dL [6.9+/-1.5 nmol/L] vs 185+/-58 mg/dL [10.3+/-3.2 nmol/L], Pvs 26,707+/-25,038, Pvs 13.6+/-7.6, Plow-GI day, subjects consumed more fiber (24.5+/-12.3 g vs 14.5+/-6.1 g, Pfat (45.7+/-12.2 g vs 76.8+/-32.4 g, Pcarbohydrate, or protein intake. In this pilot study, a low-GI diet was associated with improved diet quality and a reduction in hyperglycemia.

  16. Study on the interaction of artificial and natural food colorants with human serum albumin: A computational point of view.

    Science.gov (United States)

    Masone, Diego; Chanforan, Céline

    2015-06-01

    Due to the high amount of artificial food colorants present in infants' diets, their adverse effects have been of major concern among the literature. Artificial food colorants have been suggested to affect children's behavior, being hyperactivity the most common disorder. In this study we compare binding affinities of a group of artificial colorants (sunset yellow, quinoline yellow, carmoisine, allura red and tartrazine) and their natural industrial equivalents (carminic acid, curcumin, peonidin-3-glucoside, cyanidin-3-glucoside) to human serum albumin (HSA) by a docking approach and further refinement through atomistic molecular dynamics simulations. Due to the protein-ligand conformational interface complexity, we used collective variable driven molecular dynamics to refine docking predictions and to score them according to a hydrogen-bond criterion. With this protocol, we were able to rank ligand affinities to HSA and to compare between the studied natural and artificial food additives. Our results show that the five artificial colorants studied bind better to HSA than their equivalent natural options, in terms of their H-bonding network, supporting the hypothesis of their potential risk to human health. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Effects of small peptides, probiotics, prebiotics, and synbiotics on growth performance, digestive enzymes, and oxidative stress in orange-spotted grouper, Epinephelus coioides, juveniles reared in artificial seawater

    Science.gov (United States)

    Wang, Tao; Cheng, Yongzhou; Chen, Xiaoyan; Liu, Zhaopu; Long, Xiaohua

    2017-01-01

    Aquaculture production efficiency may increase by using feed additives. This study investigated the effects of different dietary additives [w/w: 2% small peptides, 0.01% probiotics ( Bacillus licheniformis) and 0.2% prebiotics (inulin)] on growth performance, digestive enzyme activities, and oxidative stress in juvenile Epinephelus coioides reared in artificial seawater of two salt concentrations (13.5 vs. 28.5). Weight gain rate was significantly higher in fish fed the diet supplemented with small peptides, B. licheniformis, inulin, or synbiotics than that in fish fed the basal diet; the greatest weight gain rate was found in fish fed the small peptide treatment [56.0% higher than basal diet]. Higher feed efficiency was detected in fish fed the diet supplemented with small peptides than that of fish in the other dietary treatments. Total protease activity in the stomach and intestines was highest in fish fed the small peptide-treated diet, whereas lipase activity was highest in those fed synbiotics (combination of Bacillus licheniformis and inulin) than that in fish fed the other treatments. Antioxidant enzyme (total superoxide dismutase and catalase) activities and hepatic malondialdehyde content were higher in fish receiving the dietary supplements and maintained in artificial seawater containing 13.5 salinity compared with those in the control (28.5). Hepatic catalase activity in grouper fed the diets with small peptides or synbiotics decreased significantly compared with that in control fish. Overall, the three types of additives improved growth rate of juvenile grouper and digestive enzymes activities to varying degrees but did not effectively improve antioxidant capacity under low-salinity stress conditions.

  18. Comparison of the Availability and Cost of Foods Compatible With a Renal Diet Versus an Unrestricted Diet Using the Nutrition Environment Measures Survey.

    Science.gov (United States)

    Sullivan, Catherine M; Pencak, Julie A; Freedman, Darcy A; Huml, Anne M; León, Janeen B; Nemcek, Jeanette; Theurer, Jacqueline; Sehgal, Ashwini R

    2017-05-01

    Hemodialysis patients' ability to access food that is both compatible with a renal diet and affordable is affected by the local food environment. Comparisons of the availability and cost of food items suitable for the renal diet versus a typical unrestricted diet were completed using the standard Nutrition Environment Measures Survey and a renal diet-modified Nutrition Environment Measures Survey. Cross-sectional study. Twelve grocery stores in Northeast Ohio. Availability and cost of food items in 12 categories. The mean total number of food items available differed significantly (P ≤ .001) between the unrestricted diet (38.9 ± 4.5) and renal diet (32.2 ± 4.7). The mean total cost per serving did not differ significantly (P = 0.48) between the unrestricted diet ($5.67 ± 2.50) and renal diet ($5.76 ± 2.74). The availability of renal diet food items is significantly less than that of unrestricted diet food items, but there is no difference in the cost of items that are available in grocery stores. Further work is needed to determine how to improve the food environment for patients with chronic diseases. Copyright © 2017 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

  19. [Artificial organs].

    Science.gov (United States)

    Raguin, Thibaut; Dupret-Bories, Agnès; Debry, Christian

    2017-01-01

    Research has been fighting against organ failure and shortage of donations by supplying artificial organs for many years. With the raise of new technologies, tissue engineering and regenerative medicine, many organs can benefit of an artificial equivalent: thanks to retinal implants some blind people can visualize stimuli, an artificial heart can be proposed in case of cardiac failure while awaiting for a heart transplant, artificial larynx enables laryngectomy patients to an almost normal life, while the diabetic can get a glycemic self-regulation controlled by smartphones with an artificial device. Dialysis devices become portable, as well as the oxygenation systems for terminal respiratory failure. Bright prospects are being explored or might emerge in a near future. However, the retrospective assessment of putative side effects is not yet sufficient. Finally, the cost of these new devices is significant even if the advent of three dimensional printers may reduce it. © 2017 médecine/sciences – Inserm.

  20. Diet and mobility in Early Medieval Bavaria: a study of carbon and nitrogen stable isotopes.

    Science.gov (United States)

    Hakenbeck, Susanne; McManus, Ellen; Geisler, Hans; Grupe, Gisela; O'Connell, Tamsin

    2010-10-01

    This study investigates patterns of mobility in Early Medieval Bavaria through a combined study of diet and associated burial practice. Carbon and nitrogen isotope ratios were analyzed in human bone samples from the Late Roman cemetery of Klettham and from the Early Medieval cemeteries of Altenerding and Straubing-Bajuwarenstrasse. For dietary comparison, samples of faunal bone from one Late Roman and three Early Medieval settlement sites were also analyzed. The results indicate that the average diet was in keeping with a landlocked environment and fairly limited availability of freshwater or marine resources. The diet appears not to have changed significantly from the Late Roman to the Early Medieval period. However, in the population of Altenerding, there were significant differences in the diet of men and women, supporting a hypothesis of greater mobility among women. Furthermore, the isotopic evidence from dietary outliers is supported by "foreign" grave goods and practices, such as artificial skull modification. These results reveal the potential of carbon and nitrogen isotope analysis for questions regarding migration and mobility. © 2010 Wiley-Liss, Inc.

  1. Statement Summarizing Research Findings on the Issue of the Relationship Between Food-Additive-Free Diets and Hyperkinesis in Children.

    Science.gov (United States)

    Lipton, Morris; Wender, Esther

    The National Advisory Committee on Hyperkinesis and Food Additives paper summarized some research findings on the issue of the relationship between food-additive-free diets and hyperkinesis in children. Based on several challenge studies, it is concluded that the evidence generally refutes Dr. B. F. Feingold's claim that artificial colorings in…

  2. Cognitive performance of Göttingen minipigs is affected by diet in a spatial hole-board discrimination test

    DEFF Research Database (Denmark)

    Haagensen, Annika Maria Juul; Klein, Anders Bue; Ettrup, Anders

    2013-01-01

    by both diets relative to a standard minipig diet high in carbohydrate, low in fat and sugar. The different diets did not impact levels of brain-derived neurotrophic factor in brain tissue and neither did they affect circulatory inflammation measured by concentrations of C-reactive protein and haptoglobin......Consumption of a high energy diet, containing high amounts of saturated fat and refined sugar has been associated with impairment of cognitive function in rodents and humans. We sought to contrast the effect of a high fat/cholesterol, low carbohydrate diet and a low fat, high carbohydrate....../sucrose diet, relative to a standard low fat, high carbohydrate minipig diet on spatial cognition with regards to working memory and reference memory in 24 male Göttingen minipigs performing in a spatial hole-board discrimination test. We found that both working memory and reference memory were impaired...

  3. Estimation Methodology for the Electricity Consumption with the Daylight- and Occupancy-Controlled Artificial Lighting

    DEFF Research Database (Denmark)

    Larsen, Olena Kalyanova; Jensen, Rasmus Lund; Strømberg, Ida Kristine

    2017-01-01

    Artificial lighting represents 15-30% of the total electricity consumption in buildings in Scandinavia. It is possible to avoid a large share of electricity use for lighting by application of daylight control systems for artificial lighting. Existing methodology for estimation of electricity...... consumption with application of such control systems in Norway is based on Norwegian standard NS 3031:2014 and can only provide results from a rough estimate. This paper aims to introduce a new estimation methodology for the electricity usage with the daylight- and occupancy-controlled artificial lighting...

  4. Trace element characterization of Indian vegetarian diet and its constituents by instrumental neutron activation analysis

    International Nuclear Information System (INIS)

    Singh, V.K.N.; Garg, A.N.; Burte, P.P.

    1995-01-01

    Nutritive trace elements have been determined in a typical vegetarian diet and its various components. A hospital diet, pulses and vegetables have been characterised for 18 elements. Daily intake of elements have been compared with the International diet standards. (author). 5 refs., 1 tab

  5. Artificial immune system for diabetes meal plans optimization

    Science.gov (United States)

    Prilianti, K. R.; Callista, P. B.; Setiawan, H.

    2017-03-01

    Type 2 diabetes mellitus is a disease that occurs because the body lacks of insulin or the insulin produced by the pancreas cannot work effectively such that the glucose level in the blood cannot well controlled. One of the most common causes of diabetes mellitus type 2 is obesity, therefore this disease can be controlled with the appropriate diet regarding to the daily calorie requirement. Hence, the level of blood glucose is maintained. Unfortunately, because the lack of proper diet education and facility, many people cannot work on proper daily healthy diet by their own. In this research Artificial Immune System algorithm was applied to build a model that help diabetes mellitus patient arrange their meal plans. The model can calculate the amount of daily calorie needed and arrange the appropriate daily meal plans based on it. The meal plans vary according to the patient calorie needs. The required input data are age, gender, weight, height, and type of patient daily main activity. The experiments show that this model has a good result. The result is already approaching the patients' daily calorie need, i.e. 97.6% (actual need is not less than 80% and not greater than 100%). Carbohydrate of the meal plan is 55-57% (actual need is not less than 45% and not greater than 60%) whereas the protein approximate 15-18% (actual need is not less than 15% and not greater than 20%) and fat of approximate 22-24% (actual need is not less than 20% and not greater than 25%).

  6. Skin friction related behaviour of artificial turf systems.

    Science.gov (United States)

    Tay, Sock Peng; Fleming, Paul; Hu, Xiao; Forrester, Steph

    2017-08-01

    The occurrence of skin friction related injuries is an issue for artificial turf sports pitches and remains a barrier to their acceptance. The purpose of this study was to evaluate the current industry standard Securisport® Sports Surface Tester that measures skin surface related frictional behaviour of artificial turf. Little research has been published about the device and its efficacy, despite its widespread use as a standard FIFA test instrument. To achieve a range of frictional behaviours, several "third generation" (3G) carpet and infill combinations were investigated; friction time profiles throughout the Securisport rotations were assessed in combination with independent measurements of skin roughness before and after friction testing via 3D surface scanning. The results indicated that carpets without infill had greatest friction (coefficients of friction 0.97-1.20) while those completely filled with sand or rubber had similar and lower values independent of carpet type (coefficient of friction (COF) ≈0.57). Surface roughness of a silicone skin (s-skin) decreased after friction testing, with the largest change on sand infilled surfaces, indicating an "abrasive" polishing effect. The combined data show that the s-skin is damaged in a surface-specific manner, thus the Securisport COF values appear to be a poor measure of the potential for skin abrasion. It is proposed that the change in s-skin roughness improves assessment of the potential for skin damage when players slide on artificial turf.

  7. Clinical observations on the effects of elemental diet supplementation during irradiation

    International Nuclear Information System (INIS)

    Brown, M.S.

    1980-01-01

    A study has been conducted to assess the effects of adding an elemental diet as a supplement to a standard low-roughage diet recommended to a group of patients receiving a fractionated course of abdominal irradiation. The supplement was not found to modify patient experience of radiotherapy-induced complications. (author)

  8. Long term highly saturated fat diet does not induce NASH in Wistar rats

    Directory of Open Access Journals (Sweden)

    Filippi Céline

    2007-02-01

    Full Text Available Abstract Background Understanding of nonalcoholic steatohepatitis (NASH is hampered by the lack of a suitable model. Our aim was to investigate whether long term high saturated-fat feeding would induce NASH in rats. Methods 21 day-old rats fed high fat diets for 14 weeks, with either coconut oil or butter, and were compared with rats feeding a standard diet or a methionine choline-deficient (MCD diet, a non physiological model of NASH. Results MCDD fed rats rapidly lost weight and showed NASH features. Rats fed coconut (86% of saturated fatty acid or butter (51% of saturated fatty acid had an increased caloric intake (+143% and +30%. At the end of the study period, total lipid ingestion in term of percentage of energy intake was higher in both coconut (45% and butter (42% groups than in the standard (7% diet group. No change in body mass was observed as compared with standard rats at the end of the experiment. However, high fat fed rats were fattier with enlarged white and brown adipose tissue (BAT depots, but they showed no liver steatosis and no difference in triglyceride content in hepatocytes, as compared with standard rats. Absence of hepatic lipid accumulation with high fat diets was not related to a higher lipid oxidation by isolated hepatocytes (unchanged ketogenesis and oxygen consumption or hepatic mitochondrial respiration but was rather associated with a rise in BAT uncoupling protein UCP1 (+25–28% vs standard. Conclusion Long term high saturated fat feeding led to increased "peripheral" fat storage and BAT thermogenesis but did not induce hepatic steatosis and NASH.

  9. Advances in Artificial Neural Networks – Methodological Development and Application

    Directory of Open Access Journals (Sweden)

    Yanbo Huang

    2009-08-01

    Full Text Available Artificial neural networks as a major soft-computing technology have been extensively studied and applied during the last three decades. Research on backpropagation training algorithms for multilayer perceptron networks has spurred development of other neural network training algorithms for other networks such as radial basis function, recurrent network, feedback network, and unsupervised Kohonen self-organizing network. These networks, especially the multilayer perceptron network with a backpropagation training algorithm, have gained recognition in research and applications in various scientific and engineering areas. In order to accelerate the training process and overcome data over-fitting, research has been conducted to improve the backpropagation algorithm. Further, artificial neural networks have been integrated with other advanced methods such as fuzzy logic and wavelet analysis, to enhance the ability of data interpretation and modeling and to avoid subjectivity in the operation of the training algorithm. In recent years, support vector machines have emerged as a set of high-performance supervised generalized linear classifiers in parallel with artificial neural networks. A review on development history of artificial neural networks is presented and the standard architectures and algorithms of artificial neural networks are described. Furthermore, advanced artificial neural networks will be introduced with support vector machines, and limitations of ANNs will be identified. The future of artificial neural network development in tandem with support vector machines will be discussed in conjunction with further applications to food science and engineering, soil and water relationship for crop management, and decision support for precision agriculture. Along with the network structures and training algorithms, the applications of artificial neural networks will be reviewed as well, especially in the fields of agricultural and biological

  10. Comparison of the effects of weight loss from a high-protein versus standard-protein energy-restricted diet on strength and aerobic capacity in overweight and obese men.

    Science.gov (United States)

    Wycherley, Thomas P; Buckley, Jonathan D; Noakes, Manny; Clifton, Peter M; Brinkworth, Grant D

    2013-02-01

    To compare the effects of two low-fat, hypoenergetic diets differing in carbohydrate-to-protein ratio, on strength and aerobic capacity measures in overweight and obese men. In a parallel design, 56 men (age, 45.5 ± 8.7 years; BMI, 33.6 ± 3.9 kg/m(2)) were randomly assigned to a low-fat, energy-restricted diet (7,000 kJ/day) with either high protein (HP: protein/carbohydrate/fat % energy, 35:40:25) or standard protein (SP, 17:58:25). Body weight, body composition, muscle strength and aerobic capacity were assessed at baseline and after 12 weeks. Forty-two participants completed the study (HP, n = 21; SP, n = 21). Both groups experienced similar reductions in body weight (HP, -10.7 ± 5.3 kg [-9.8%]; SP, -8.7 ± 3.5 kg [-8.4%]) and fat-free mass (HP, -2.8 ± 3.6 kg; SP, -3.2 ± 2.7 kg; P 0.14 time × group interaction). There was a trend for a greater reduction in fat mass in the HP diet group, (-7.7 ± 4.3 kg [-21.2%] vs. -5.4 ± 3.3 kg [-15.1%]; P diet effect (P ≤ 0.23 time × group interaction). In overweight and obese men, both a HP and SP diet reduced body weight and improved body composition with similar effects on strength and aerobic capacity.

  11. Effects of low calcium plus high aluminum diet on magnesium and calcium contents in spinal cord and trabecular bone of rats

    Energy Technology Data Exchange (ETDEWEB)

    Yasui, Masayuki; Ota, Kiichiro [Wakayama Medical Coll. (Japan); Sasajima, Kazuhisa

    1998-01-01

    Current epidemiological surveys in the Western Pacific area and Kii Peninsula have suggested that low calcium (Ca), magnesium (Mg), and high aluminum (Al) and manganese (Mn) in river, soil and drinking water may be implicated in the pathogenetic process of amyotrophic lateral sclerosis (ALS) and parkinsonism-dementia (PD). The condition of unbalanced minerals was experimentally duplicated in this study using rats. Male Wistar rats, weighing 200 g, were maintained for 60 days on the following diets: (A) standard diet, (B) low Ca diet, (C) low Ca diet with high Al. Magnesium concentration was determined in spinal cord and trabecular bone using inductively coupled plasma emission spectrometry (ICP) and the calcium concentration was determined using neutron activation method. In the group maintained on low Ca high Al diet, magnesium content of the spinal cord was lower than the group fed standard diet. Also, magnesium content of lumbar bone showed lower values in the unbalanced diet group fed low Ca high Al diet than those in the standard diet and low Ca diet groups. Calcium content of spinal cord was highest in rats maintained on low Ca high Al diet. Calcium content in lumbar bone of rats significantly decreased in rats maintained on the low Ca diet (group B and C) compared to rats given a standard diet (group A). Our data indicate that low Ca and high Al dietary intake influence Mg concentration in bone and central nervous system (CNS) tissues and that low Ca and high Al diet diminish Mg in bone and CNS tissues, thereby inducing loss of calcification in bone and degeneration of CNS tissues due to disturbance of the normal biological effects of Mg. (author)

  12. Effect of bacterial or porcine lipase with low- or high-fat diets on nutrient absorption in pancreatic-insufficient dogs.

    Science.gov (United States)

    Suzuki, A; Mizumoto, A; Rerknimitr, R; Sarr, M G; DiMango, E P

    1999-02-01

    Treatment of human exocrine pancreatic insufficiency is suboptimal. This study assessed the effects of bacterial lipase, porcine lipase, and diets on carbohydrate, fat, and protein absorption in pancreatic-insufficient dogs. Dogs were given bacterial or porcine lipase and 3 diets: a 48% carbohydrate, 27% fat, and 25% protein standard diet; a high-carbohydrate, low-fat, and low-protein diet; or a low-carbohydrate, high-fat, and high-protein diet (66%/18%/16% and 21%/43%/36% calories). With the standard diet, coefficient of fat absorption increased dose-dependently with both lipases (P vs. low-fat and -protein diet). There were no interactions among carbohydrate, fat, and protein absorption. Correcting steatorrhea requires 75 times more porcine than bacterial lipase (18 vs. 240 mg). High-fat and high-protein diets optimize fat absorption with both enzymes. High-fat diets with bacterial or porcine lipase should be evaluated in humans with pancreatic steatorrhea.

  13. Nutritional treatment of cancer cachexia in rats. Use of a diet formulated with a crayfish enzymatic extract.

    Science.gov (United States)

    Cremades, Olga; Parrado, Juan; Jover, María; Collantes de Terán, Laura; Gutiérrez, Juan Francisco; Bautista Palomas, Juan D

    2007-09-01

    Terminal cancer-associated cachexia, characterized by a marked weight loss, anorexia, asthenia and anemia, is usually associated with a malnutrition status. To investigate whether a diet formulated with a crayfish enzymatic extract, enriched in essential amino acids, omega-3 fatty acids, and astaxanthin, would be effective for the treatment of cancer-associated cachexias, by decreasing mortality and morbidity rates in cachectic rats and/or improving survival. Two types of diet were used: a standard diet and one formulated with crayfish enzymatic extract. Rats were divided into two groups (24 animals per group): one without tumor (T-) and the other with tumor (T+) (AH-130 Yoshida ascites hepatoma). Each group was further divided into two subgroups (12 animals per subgroup). Two subgroups (T-(standard) and T+(standard)) were fed the standard diet and the other two (T-(CFEE) and T+(CFEE)) the crayfish enzymatic extract one for four weeks, after which different tissue and plasma parameters were studied. The implantation of the tumor resulted in a considerable loss of muscle and adipose tissue mass in both groups, but the loss of muscle and fat was lower in the group fed the crayfish enzymatic extract diet. There was also a concomitant increase in the plasma concentration of TNF-alpha, although the increase was smaller in the crayfish enzymatic extract-treated group. This study shows that although the treatment of cachetic rats with the crayfish enzymatic extract diet did not revert the cachexia, it increased survival (57.1% vs. 25.9% in the group treated with crayfish enzymatic extract and standard diets, respectively) and meliorated the cachexia symptoms--anorexia and body mass loss (muscle and adipose tissue).

  14. The Effects of a Low-Carbohydrate Diet vs. a Low-Fat Diet on Novel Cardiovascular Risk Factors: A Randomized Controlled Trial

    Directory of Open Access Journals (Sweden)

    Tian Hu

    2015-09-01

    Full Text Available Increasing evidence supports a low-carbohydrate diet for weight loss and improvement in traditional cardiovascular disease (CVD markers. Effects on novel CVD markers remain unclear. We examined the effects of a low-carbohydrate diet (<40 g/day; n = 75 versus a low-fat diet (<30% kcal/day from total fat, <7% saturated fat; n = 73 on biomarkers representing inflammation, adipocyte dysfunction, and endothelial dysfunction in a 12 month clinical trial among 148 obese adults free of diabetes and CVD. Participants met with a study dietitian on a periodic basis and each diet group received the same behavioral curriculum which included dietary instruction and supportive counseling. Eighty percent of participants completed the intervention. At 12 months, participants on the low-carbohydrate diet had significantly greater increases in adiponectin (mean difference in change, 1336 ng/mL (95% CI, 342 to 2330 ng/mL; p = 0.009 and greater decreases in intercellular adhesion molecule-1 concentrations (−16.8 ng/mL (−32.0 to −1.6 ng/mL; p = 0.031 than those on the low-fat diet. Changes in other novel CVD markers were not significantly different between groups. In conclusion, despite the differences in weight changes on diets, a low-carbohydrate diet resulted in similar or greater improvement in inflammation, adipocyte dysfunction, and endothelial dysfunction than a standard low-fat diet among obese persons.

  15. The effects of ionizing radiation in the rat's mandibular bone freeding the hypernomic calcium-deficient diet

    International Nuclear Information System (INIS)

    Hasegawa, Gen; Kurita, Akihiko; Nasu, Masanori; Furumoto, Keiichi

    1994-01-01

    The mandibles of rats in a group maintained on the Ca-deficient diet for a long period were irradiated with 30 Gy. To study the effects of radiation, serum Ca and inorganic phosphorus levels were determined for 3 weeks, and the data were compared with findings obtained from rats maintained on a standard diet by autoradiography using 45 Ca and microradiography. The serum Ca level tended to decrease with time after irradiation in the irradiated group maintained on the Ca-deficient diet, but there was no significant difference between the group maintained on the Ca-deficient diet and the group maintained on the standard diet. The serum inorganic phosphorus levels were almost constant throughout the observation period in both the non-irradiated and radiated groups regardless of diet. Uptake of 45 Ca was examined by autoradiography. Both the non-irradiated and irradiated groups maintained on the Ca-deficient diet showed intense 45 Ca uptake, there was almost no difference between these groups in photographic density or in weekly changes after irradiation. The microradiographic study of bone trabeculae revealed only slight changes in the bone cortex after irradiation in the group maintained on the standard diet. On day 3 after irradiation both thinning and roughness of the trabeculae were observed in the interradicular septa and incisal inferior margin and on day 7 in cancellous bone. In the groups maintained on the Ca-deficient diet, marked thinning and roughness of the trabeculae were observed mainly in the cancellous bone. (author)

  16. Bland diet

    Science.gov (United States)

    ... bland diet; Nausea - bland diet; Diarrhea - bland diet; Peptic ulcer - bland diet ... be used alongside lifestyle changes to help treat ulcers, heartburn, ... stomach or intestinal surgery. A bland diet includes foods ...

  17. Efficacy and tolerance of sodium phosphates oral solution after diet liberalization.

    Science.gov (United States)

    Scott, Sherrie R; Raymond, Patricia L; Thompson, William O; Galt, Deborah J B

    2005-01-01

    Bowel cleansing regimens commonly require adherence to liquid diets for 24 to 48 hours before examination, which often leads to poor compliance, reduced cleansing, and ultimately inadequate examinations. The authors investigated the efficacy and tolerability of diet liberalization before bowel cleansing with sodium phosphates oral solution. Two hundred patients were randomized into two treatment groups. One group received the standard light breakfast followed by clear liquids the day before colonoscopy; the second had a normal breakfast followed by a low-residue lunch the day before colonoscopy. Both groups had the same bowel preparation with sodium phosphates oral solution (2 x 45-mL, 7 p.m./6 a.m.). There was no difference in clinical efficacy between the two diet regimens (excellent/good in 93% standard, 95% low-residue). Fewer patients receiving the low-residue diet reported hunger, and more patients receiving the low-residue regimen reported energy to perform usual activities. This study supports offering patients a regular breakfast and a low-residue lunch before bowel cleansing with sodium phosphates oral solution.

  18. Development of large intestinal attaching and effacing lesions in pigs in association with the feeding of a particular diet.

    Science.gov (United States)

    Neef, N A; McOrist, S; Lysons, R J; Bland, A P; Miller, B G

    1994-10-01

    Hysterotomy-derived piglets were kept in gnotobiotic isolators and artificially colonized at 7 days of age with an adult bovine enteric microflora. At 3 weeks of age, the pigs were transferred to conventional experimental accommodation and weaned, either onto a solid diet that had been associated with field cases of typhlocolitis in pigs or onto a solid control diet. At necropsy at 5 weeks of age, groups of pigs fed the diet associated with field cases of typhlocolitis were found to have developed typhlocolitis. This was absent from the groups fed the control diet. The typhlocolitis was characterized by attaching and effacing lesions typical of those described following experimental inoculation of various species with enteropathogenic Escherichia coli. A nonverocytotoxic, eae probe-positive E. coli serotype O116 was isolated from pigs on the colitis-associated diet but not from any of the pigs on the control diet. Coliform bacteria attached to the colonic lesions reacted with polyclonal antiserum to E. coli O116 in an immunoperoxidase assay of histological sections of affected tissue. No reaction with this antiserum was observed in corresponding tissue sections taken from pigs on the control diet. No colon lesions were observed in germfree pigs fed either of the diets. It is postulated that proliferation and possibly expression of pathogenicity of the attaching and effacing E. coli responsible for the lesions are strongly influenced by diet.

  19. Comparison of standard resampling methods for performance estimation of artificial neural network ensembles

    OpenAIRE

    Green, Michael; Ohlsson, Mattias

    2007-01-01

    Estimation of the generalization performance for classification within the medical applications domain is always an important task. In this study we focus on artificial neural network ensembles as the machine learning technique. We present a numerical comparison between five common resampling techniques: k-fold cross validation (CV), holdout, using three cutoffs, and bootstrap using five different data sets. The results show that CV together with holdout $0.25$ and $0.50$ are the best resampl...

  20. Quantitative Analysis of Ca, Mg, and K in the Roots of Angelica pubescens f. biserrata by Laser-Induced Breakdown Spectroscopy Combined with Artificial Neural Networks

    Science.gov (United States)

    Wang, J.; Shi, M.; Zheng, P.; Xue, Sh.; Peng, R.

    2018-03-01

    Laser-induced breakdown spectroscopy has been applied for the quantitative analysis of Ca, Mg, and K in the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan used in traditional Chinese medicine. Ca II 317.993 nm, Mg I 517.268 nm, and K I 769.896 nm spectral lines have been chosen to set up calibration models for the analysis using the external standard and artificial neural network methods. The linear correlation coefficients of the predicted concentrations versus the standard concentrations of six samples determined by the artificial neural network method are 0.9896, 0.9945, and 0.9911 for Ca, Mg, and K, respectively, which are better than for the external standard method. The artificial neural network method also gives better performance comparing with the external standard method for the average and maximum relative errors, average relative standard deviations, and most maximum relative standard deviations of the predicted concentrations of Ca, Mg, and K in the six samples. Finally, it is proved that the artificial neural network method gives better performance compared to the external standard method for the quantitative analysis of Ca, Mg, and K in the roots of Angelica pubescens.

  1. EXPERIMENTAL RESEARCHES OF ELECTRO-THERMAL RESISTIBILITY OF SEND-OFFS AND CABLES TO ACTION RATIONED ON THE INTERNATIONAL STANDARD OF IEC 62305-1-2010 OF APERIODIC IMPULSE OF CURRENT OF ARTIFICIAL LIGHTNING

    Directory of Open Access Journals (Sweden)

    M.I. Baranov

    2016-03-01

    Full Text Available Purpose. Experimental researches of electro-thermal resistibility of cable-explorer products, applied in the power electric circuits of objects of electric-power industry, to action on its copper and aluminum parts bearings a current rationed on the International Standard of IEC 62305-1-2010 aperiodic impulse 10/350 μs of current of artificial lightning. Methodology. Electrophysics bases of technique of high tensions and high pulsed currents (HPC, and also scientific and technical bases of planning of devices of high-voltage impulsive technique and measuring HPC in them. Results. Experimental a way the quantitative levels of maximal values maximum of possible and critical closenesses of aperiodic impulse 10/350 μs of current of artificial lightning with rationed on the international standard of IEC 62305-1-2010 peak-temporal parameters and admittances on them in copper (aluminum parts bearings a current of send-offs and cables with a polyethylene (PET and polyvinylchloride (PVCH isolation. Originality. First in world practice on the unique powerful high-voltage generator of HPC of artificial lightning experimental researches of resistibility to lightning of pre-production models of send-offs (cables are conducted with copper (aluminum tendons, PET and PVCH by an isolation, in-use in power electric circuits of electric-power industry objects. Practical value. The use in practice of protecting from lightning of the got results will allow substantially to promote functional and fire-prevention safety of engineering communications of objects of industrial electroenergy in the conditions of action on them of short shots of linear lightning.

  2. Bioavailability of lead in rats fed human diets

    International Nuclear Information System (INIS)

    Kostial, K.; Kello, D.

    1979-01-01

    The bioavailability of lead was studied in rats fed various baby foods (Babymix-turkey, Babymix-vegetables, Frutolino-fruit, Frutamix-bananas, Babyron-S-26, Truefood), cow's milk, bread, liver and standard rat diet. Lead absorption was determined by measuring the whole body retention of 203 Pb 6 days after a single oral application. Highest absorption values ranging from 17 to 20% were obtained in animals fed cow's milk and fruit foods. Rats on other human diets absorbed between 3 and 8% of the radioactive lead dose. Only in animals on rat diet lead absorption was below 1%. It is concluded that rats fed human diets show absorption values similar to those in humans. This might indicate that the bioavailability of lead is primarily dependent on dietary habits. This experimental model, if confirmed by further work, might be useful for obtaining preliminary data on the bioavailability of metals from various foods

  3. Effectiveness of artificial diet enriched by spinach extract on molting stimulation to produce soft shell crab

    Directory of Open Access Journals (Sweden)

    Siti Aslamyah

    2011-01-01

    Full Text Available Artificial feed is an alternative media applications spinach extract (EB that is known to contain molting stimulant. However, utilization of the artificial feed is related to its expensive cost, with a very high protein concentration since it's mainly produced from fish based materials, so need to be studied artificial feed formulation with substitution of vegetable material in stimulating molting and growth of mud crabs. Four formula artificial feed enriched EB (700 ng/g crab used in this study were feed A (fish, crab shells, and cassava, feed B (fish, silage, shell crab, and cassava, feed C (fish, silage, shell crab, soy flour, and cassava, and feed D (fish, silage, shell crab, soy flour, corn starch, and pollard, trash fish and feed A without EB as control. During the test, mud crab intermolt phase was culture individually in crab box placed in pond. The results showed that the percentage of molting and weight growth in their respective in the feed A (44% and 41.96%; feed B (56% and 31.57%; feed C (74% and 23.20%; feed D (50% and 39.15%; trash feed control (24% and 50.66%; and feed A without EB (28% and 35.11%. An opposite phenomenon, where the feed C with the highest percentage of molting but with the lowest growth rate, the opposite occurs in the control of trash feed. This is apparently the effect of spinach extract as a stimulant molting, where performance can be optimized with a complete and balance nutrient composition. This prediction is supported by the analysis of protein content of crabs tested at the highest feed C treatment compared with the control feed. Key words: spinach extract, soft shell crab, molting, artificial feed, growth   ABSTRAK Pakan buatan merupakan alternatif media aplikasi ekstrak bayam (EB yang diketahui mengandung stimulan molting.  Namun demikian, pakan buatan yang digunakan masih mahal dengan kandungan protein yang tinggi, karena berbahan dasar ikan, sehingga perlu dikaji formulasi pakan buatan dengan

  4. Associations between nutritional quality of meals and snacks assessed by the Food Standards Agency nutrient profiling system and overall diet quality and adiposity measures in British children and adolescents.

    Science.gov (United States)

    Murakami, Kentaro

    2018-05-01

    This cross-sectional study examined how the nutritional quality of meals and snacks was associated with overall diet quality and adiposity measures. Based on 7-d weighed dietary record data, all eating occasions were divided into meals or snacks based on time (meals: 06:00-09:00 h, 12:00-14:00 h, and 17:00-20:00 h; snacks: others) or contribution to energy intake (meals: ≥15%; snacks: quality of meals and snacks was assessed as the arithmetical energy intake-weighted means of the Food Standards Agency (FSA) nutrient profiling system score of each food and beverage consumed, based on the contents of energy, saturated fatty acid, total sugar, sodium, fruits/vegetables/nuts, dietary fiber, and protein. Regardless of the definition of meals and snacks, higher FSA score (lower nutritional quality) of meals was inversely associated with overall diet quality assessed by the Mediterranean diet score in both children and adolescents (P quality of meals, but not snacks, assessed by the FSA score was associated with lower overall diet quality, whereas no consistent associations were observed with regard to adiposity measures. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Diet-Induced Ketosis Improves Cognitive Performance in Aged Rats

    Science.gov (United States)

    Xu, Kui; Sun, Xiaoyan; Eroku, Bernadette O.; Tsipis, Constantinos P.; Puchowicz, Michelle A.; LaManna, Joseph C.

    2010-01-01

    Aging is associated with increased susceptibility to hypoxic/ischemic insult and declines in behavioral function which may be due to attenuated adaptive/defense responses. We investigated if diet-induced ketosis would improve behavioral performance in the aged rats. Fischer 344 rats (3- and 22-month-old) were fed standard (STD) or ketogenic (KG) diet for 3 weeks and then exposed to hypobaric hypoxia. Cognitive function was measured using the T-maze and object recognition tests. Motor function was measured using the inclined-screen test. Results showed that KG diet significantly increased blood ketone levels in both young and old rats. In the aged rats, the KG diet improved cognitive performance under normoxic and hypoxic conditions; while motor performance remained unchanged. Capillary density and HIF-1α levels were elevated in the aged ketotic group independent of hypoxic challenge. These data suggest that diet-induced ketosis may be beneficial in the treatment of neurodegenerative conditions. PMID:20204773

  6. Artificial intelligence

    CERN Document Server

    Ennals, J R

    1987-01-01

    Artificial Intelligence: State of the Art Report is a two-part report consisting of the invited papers and the analysis. The editor first gives an introduction to the invited papers before presenting each paper and the analysis, and then concludes with the list of references related to the study. The invited papers explore the various aspects of artificial intelligence. The analysis part assesses the major advances in artificial intelligence and provides a balanced analysis of the state of the art in this field. The Bibliography compiles the most important published material on the subject of

  7. Gluten-free but also gluten-enriched (gluten+) diet prevent diabetes in NOD mice; the gluten enigma in type 1 diabetes.

    Science.gov (United States)

    Funda, David P; Kaas, Anne; Tlaskalová-Hogenová, Helena; Buschard, Karsten

    2008-01-01

    Environmental factors such as nutrition or exposure to infections play a substantial role in the pathogenesis of type 1 diabetes (T1D). We have previously shown that gluten-free, non-purified diet largely prevented diabetes in non-obese diabetic (NOD) mice. In this study we tested hypothesis that early introduction of gluten-enriched (gluten+) diet may increase diabetes incidence in NOD mice. Standard, gluten-free, gluten+ modified Altromin diets and hydrolysed-casein-based Pregestimil diet were fed to NOD females and diabetes incidence was followed for 310 days. Insulitis score and numbers of gut mucosal lymphocytes were determined in non-diabetic animals. A significantly lower diabetes incidence (p gluten-free diet (5.9%, n = 34) and Pregestimil diet (10%, n = 30) compared to mice on the standard Altromin diet (60.6%, n = 33). Surprisingly, gluten+ diet also prevented diabetes incidence, even at the level found with the gluten-free diet (p gluten+, gluten-free, Pregestimil) diets, did that slightly later compared to those on the standard diet. Lower insulitis score compared to control mice was found in non-diabetic NOD mice on the gluten-free, and to a lesser extent also gluten+ and Pregestimil diets. No substantial differences in the number of CD3(+), TCR-gammadelta(+), and IgA(+) cells in the small intestine were documented. Gluten+ diet prevents diabetes in NOD mice at the level found with the non-purified gluten-free diet. Possible mechanisms of the enigmatic, dual effect of dietary gluten on the development of T1D are discussed. 2007 John Wiley & Sons, Ltd

  8. Paleo Diet

    OpenAIRE

    Kaucká, Petra

    2012-01-01

    Topic: Paleo Diet Objectives: The aim of bachelor thesis is to study available literature about Paleo Diet and evaluated it. Then determine whether there is awareness of Paleo Diet in Czech republic. In addition, find out whether there is any experience in dieting according to Paleo Diet and whether Paleo Diet coul be applied in our environment. Methods: As a source of information served a survey. The research group consists of respondents who should have any experience in dieting according t...

  9. Performance of broiler chicken fed varied nutrient density diets supplemented with direct fed microbial

    Directory of Open Access Journals (Sweden)

    Katoch S.

    2013-01-01

    Full Text Available Comparative dietary response of different isolated strains (Direct fed microbial- DFM of lactobacilli, streptococci and yeast isolated from leopard feces (Panthera leo was studied as probiotic in poultry broiler birds reared as per varied mineral densities viz. calcium and phosphorus. Various treatments consisted of T0 (Control, culture medium, T1 (Lactobacillus casei + Streptococcus fecalis + Saccharomyces cerevisiae offered standard formulated diet D1, T2 - Control (Culture medium offered ten percent lower calcium and phosphorus diet D2, T3 (Lactobacillus casei + Streptococcus fecalis + Saccharomyces cerevisiae offered ten percent lower calcium and phosphorus diet D2. Growth results obtained during the starter phase (1st to 3rd week exhibited higher gain in live body weight and lower feed conversion ratio, both by DFM supplemented treatment T1 offered standard formulated diet D1 and treatment T3 offered experimentally formulated mineral (Ca and P deficient (10% diet D2 compared to respective control T0 and T2. The obtained results revealed a significantly higher growth performance in treatment T1 compared to its control T0 where a higher growth in treatment T3 offered experimentally formulated mineral (Ca and P deficient (10% diet D2 supplemented with isolated DFM compared to its control T2 was exhibited. Treatment groups T1 and T3 supplemented with isolated DFM exhibited a better intestinal micro flora balance, effective colonization and higher count in the intestinal tract with higher calcium and phosphorus retention in the digestibility studies. Thus, it was found that supplementation of isolated DFM has the potential to improve biological growth performance of poultry broiler birds offered both standard formulated diet D1, as well as mineral deficient diet D2. [Projekat Ministarstva nauke Republike Srbije, br. III 46002

  10. Artificial Intelligence Software Engineering (AISE) model

    Science.gov (United States)

    Kiss, Peter A.

    1990-01-01

    The American Institute of Aeronautics and Astronautics has initiated a committee on standards for Artificial Intelligence. Presented are the initial efforts of one of the working groups of that committee. A candidate model is presented for the development life cycle of knowledge based systems (KBSs). The intent is for the model to be used by the aerospace community and eventually be evolved into a standard. The model is rooted in the evolutionary model, borrows from the spiral model, and is embedded in the standard Waterfall model for software development. Its intent is to satisfy the development of both stand-alone and embedded KBSs. The phases of the life cycle are shown and detailed as are the review points that constitute the key milestones throughout the development process. The applicability and strengths of the model are discussed along with areas needing further development and refinement by the aerospace community.

  11. Artificial enzyme-powered microfish for water-quality testing.

    Science.gov (United States)

    Orozco, Jahir; García-Gradilla, Victor; D'Agostino, Mattia; Gao, Wei; Cortés, Allan; Wang, Joseph

    2013-01-22

    We present a novel micromotor-based strategy for water-quality testing based on changes in the propulsion behavior of artificial biocatalytic microswimmers in the presence of aquatic pollutants. The new micromotor toxicity testing concept mimics live-fish water testing and relies on the toxin-induced inhibition of the enzyme catalase, responsible for the biocatalytic bubble propulsion of tubular microengines. The locomotion and survival of the artificial microfish are thus impaired by exposure to a broad range of contaminants, that lead to distinct time-dependent irreversible losses in the catalase activity, and hence of the propulsion behavior. Such use of enzyme-powered biocompatible polymeric (PEDOT)/Au-catalase tubular microengine offers highly sensitive direct optical visualization of changes in the swimming behavior in the presence of common contaminants and hence to a direct real-time assessment of the water quality. Quantitative data on the adverse effects of the various toxins upon the swimming behavior of the enzyme-powered artificial swimmer are obtained by estimating common ecotoxicological parameters, including the EC(50) (exposure concentration causing 50% attenuation of the microfish locomotion) and the swimmer survival time (lifetime expectancy). Such novel use of artificial microfish addresses major standardization and reproducibility problems as well as ethical concerns associated with live-fish toxicity assays and hence offers an attractive alternative to the common use of aquatic organisms for water-quality testing.

  12. Cotton genotypes selection through artificial neural networks.

    Science.gov (United States)

    Júnior, E G Silva; Cardoso, D B O; Reis, M C; Nascimento, A F O; Bortolin, D I; Martins, M R; Sousa, L B

    2017-09-27

    Breeding programs currently use statistical analysis to assist in the identification of superior genotypes at various stages of a cultivar's development. Differently from these analyses, the computational intelligence approach has been little explored in genetic improvement of cotton. Thus, this study was carried out with the objective of presenting the use of artificial neural networks as auxiliary tools in the improvement of the cotton to improve fiber quality. To demonstrate the applicability of this approach, this research was carried out using the evaluation data of 40 genotypes. In order to classify the genotypes for fiber quality, the artificial neural networks were trained with replicate data of 20 genotypes of cotton evaluated in the harvests of 2013/14 and 2014/15, regarding fiber length, uniformity of length, fiber strength, micronaire index, elongation, short fiber index, maturity index, reflectance degree, and fiber quality index. This quality index was estimated by means of a weighted average on the determined score (1 to 5) of each characteristic of the HVI evaluated, according to its industry standards. The artificial neural networks presented a high capacity of correct classification of the 20 selected genotypes based on the fiber quality index, so that when using fiber length associated with the short fiber index, fiber maturation, and micronaire index, the artificial neural networks presented better results than using only fiber length and previous associations. It was also observed that to submit data of means of new genotypes to the neural networks trained with data of repetition, provides better results of classification of the genotypes. When observing the results obtained in the present study, it was verified that the artificial neural networks present great potential to be used in the different stages of a genetic improvement program of the cotton, aiming at the improvement of the fiber quality of the future cultivars.

  13. An extra virgin olive oil rich diet intervention ameliorates the nonalcoholic steatohepatitis induced by a high-fat "Western-type" diet in mice.

    Science.gov (United States)

    Jurado-Ruiz, Enrique; Varela, Lourdes M; Luque, Amparo; Berná, Genoveva; Cahuana, Gladys; Martinez-Force, Enrique; Gallego-Durán, Rocío; Soria, Bernat; de Roos, Baukje; Romero Gómez, Manuel; Martín, Franz

    2017-03-01

    We evaluated the protective effect of extra virgin olive oil (EVOO) in high-fat diets (HFDs) on the inflammatory response and liver damage in a nonalcoholic fatty liver disease (NAFLD) mouse model. C57BL/6J mice were fed a standard diet or a lard-based HFD (HFD-L) for 12 wk to develop NAFLD. HFD-fed mice were then divided into four groups and fed for 24 wk with the following: HFD-L, HFD-EVOO, HFD based on phenolics-rich EVOO, and reversion (standard diet). HFD-L-induced metabolic disorders were alleviated by replacement of lard with EVOO. EVOO diets improved plasma lipid profile and reduced body weight, plasma and epididymal fat INF-γ, IL-6 and leptin levels, and macrophage infiltration. Moreover, NAFLD activity scores were reduced. The liver lipid composition showed an increase in MUFAs, especially oleic acid, and a decrease in saturated fatty acids. Hepatic adiponutrin and Cd36 gene expression was upregulated in the EVOO groups. Liver ingenuity pathway analysis revealed in EVOO groups regulation of proteins involved in lipid metabolism, small molecule biochemistry, gastrointestinal disease, and liver regeneration. Dietary EVOO could repair HFD-induced hepatic damage, possibly via an anti-inflammatory effect in adipose tissue and modifications in the liver lipid composition and signaling pathways. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. FORECASTING KUALA LUMPUR COMPOSITE INDEX: EVIDENCE OF THE ARTIFICIAL NEURAL NETWORK AND ARIMA

    OpenAIRE

    Sukmana, Raditya; Solihin, Mahmud Iwan

    2007-01-01

    The aim of this paper is to use, compare, and analyze two forecasting technique: namelyAuto Regressive Integrated Moving Average(ARIMA) and Artificial NeuralNetwork(ANN) using Kuala Lumpur Composite Index(KLCI) in Malaysia. ArtificialNeural Network is used because of its popularity of capturing the volatility patterns innonlinear time series while ARIMA used since it is a standard method in the forecastingtool. Daily data of Kuala Lumpur Composite Index from 4 January 1999 to 26 September2005...

  15. Forecasting Kuala Lumpur Composite Index: Evidence of the Artificial Neural Network and Arima

    OpenAIRE

    Mahmud Iwan, Raditya Sukmana,

    2007-01-01

    The aim of this paper is to use, compare, and analyze two forecasting technique: namely Auto Regressive Integrated Moving Average(ARIMA) and Artificial Neural Network(ANN) using Kuala Lumpur Composite Index(KLCI) in Malaysia. Artificial Neural Network is used because of its popularity of capturing the volatility patterns in nonlinear time series while ARIMA used since it is a standard method in the forecasting tool. Daily data of Kuala Lumpur Composite Index from 4 January 1999 to 26 Septembe...

  16. Diet History Questionnaire Paper-based Forms

    Science.gov (United States)

    DHQ-1 is the standard version of the NCI's Diet History Questionnaire. It was originally printed in 1998, reprinted in 2002 with minor changes to the front page and the development of a Spanish translation, and reprinted again in 2007 with changes to the Today's Date field to include the years 2007-2011.

  17. Gluten-free but also gluten-enriched (gluten+) diet prevent diabetes in NOD mice; the gluten enigma in type 1 diabetes

    DEFF Research Database (Denmark)

    Funda, D.P.; Kaas, A.; Tlaskalova-Hogenova, H.

    2008-01-01

    BACKGROUND: Environmental factors such as nutrition or exposure to infections play a substantial role in the pathogenesis of type 1 diabetes (T1D). We have previously shown that gluten-free, non-purified diet largely prevented diabetes in non-obese diabetic (NOD) mice. In this study we tested...... hypothesis that early introduction of gluten-enriched (gluten+) diet may increase diabetes incidence in NOD mice. METHODS: Standard, gluten-free, gluten+ modified Altromin diets and hydrolysed-casein-based Pregestimil diet were fed to NOD females and diabetes incidence was followed for 310 days. Insulitis...... score and numbers of gut mucosal lymphocytes were determined in non-diabetic animals. RESULTS: A significantly lower diabetes incidence (p diet (5.9%, n = 34) and Pregestimil diet (10%, n = 30) compared to mice on the standard Altromin diet (60.6%, n...

  18. Iron bioavailability of Lupinus rotundiflorus seeds and roots in low-iron-diet treated rats

    Directory of Open Access Journals (Sweden)

    Elia Herminia VALDÉS MIRAMONTES

    Full Text Available ABSTRACT Objective To evaluate iron bioavailability of roots and cooked seeds of Lupinus rotundiflorus for human consumption using a low-iron-diet rat model. Methods A hemoglobin depletion–repletion test was performed using rats. A standard diet containing 8mg kg-1 of iron was used. Three experimental diets were prepared based on the standard diet: 2.3g of root flour added to D1, 21.5g cooked seed flour added to D2, and 0.03g of ferrous sulfate added to D3 (control diet, adjusting iron concentration of the diets to 24mg kg-1. Hemoglobin regeneration efficiency was used to measure iron bioavailability. Results Hemoglobin regeneration efficiency showed values of 13.80+2.49%, 13.70+1.60% and 18.38+1.56 in D1, D2 and D3 respectively, and biological relative values of 72.8, 75.08, and 100.00% (.<0.05. Conclusion Roots and cooked seeds of Lupinus rotundiflorus showed potential iron bioavailability, despite being a vegetal source, which could also encourage the study of other species of lupin as a source of iron.

  19. Effects of high-fat diet and fructose-rich diet on obesity, dyslipidemia and hyperglycemia in the WBN/Kob-Leprfa rat, a new model of type 2 diabetes mellitus.

    Science.gov (United States)

    Namekawa, Junichi; Takagi, Yoshiichi; Wakabayashi, Kaoru; Nakamura, Yuki; Watanabe, Ayaka; Nagakubo, Dai; Shirai, Mitsuyuki; Asai, Fumitoshi

    2017-06-10

    Obesity and type 2 diabetes mellitus (T2DM) are occurring at epidemic-like rates, and these epidemics appear to have emerged largely from changes in daily diet. In the present study, we compared effects of high-fat diet (HFD) and fructose-rich diet (FRD) in WBN/Kob-Lepr fa (WBKDF) rats that spontaneously develop obesity, dyslipidemia and T2DM. After a 4-week feeding of each diet, WBKDF-HFD and WBKDF-FRD rats exhibited aggravated obesity and dyslipidemia compared with WBKDF rats fed standard diet (STD). In contrast, hyperglycemia developed in WBKDF-STD rats was significantly inhibited in WBKDF-FRD rats, but not in WBKDF-HFD rats. The present study demonstrated that the 4-week feeding of HFD and FRD caused diet-induced obesity with a distinct phenotype in the glucose metabolism in WBKDF rats.

  20. Comparison of a carbohydrate-free diet vs. fasting on plasma glucose, insulin and glucagon in type 2 diabetes.

    Science.gov (United States)

    Nuttall, Frank Q; Almokayyad, Rami M; Gannon, Mary C

    2015-02-01

    Hyperglycemia improves when patients with type 2 diabetes are placed on a weight-loss diet. Improvement typically occurs soon after diet implementation. This rapid response could result from low fuel supply (calories), lower carbohydrate content of the weight-loss diet, and/or weight loss per se. To differentiate these effects, glucose, insulin, C-peptide and glucagon were determined during the last 24 h of a 3-day period without food (severe calorie restriction) and a calorie-sufficient, carbohydrate-free diet. Seven subjects with untreated type 2 diabetes were studied. A randomized-crossover design with a 4-week washout period between arms was used. Results from both the calorie-sufficient, carbohydrate-free diet and the 3-day fast were compared with the initial standard diet consisting of 55% carbohydrate, 15% protein and 30% fat. The overnight fasting glucose concentration decreased from 196 (standard diet) to 160 (carbohydrate-free diet) to 127 mg/dl (fasting). The 24 h glucose and insulin area responses decreased by 35% and 48% on day 3 of the carbohydrate-free diet, and by 49% and 69% after fasting. Overnight basal insulin and glucagon remained unchanged. Short-term fasting dramatically lowered overnight fasting and 24 h integrated glucose concentrations. Carbohydrate restriction per se could account for 71% of the reduction. Insulin could not entirely explain the glucose responses. In the absence of carbohydrate, the net insulin response was 28% of the standard diet. Glucagon did not contribute to the metabolic adaptations observed. Published by Elsevier Inc.

  1. Artificial Leaf Based on Artificial Photosynthesis for Solar Fuel Production

    Science.gov (United States)

    2017-06-30

    collect light energy and separate charge for developing new types of nanobiodevices to construct ”artificial leaf” from solar to fuel. or Concept of...AFRL-AFOSR-JP-TR-2017-0054 Artificial Leaf Based on Artificial Photosynthesis for Solar Fuel Production Mamoru Nango NAGOYA INSTITUTE OF TECHNOLOGY...display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ORGANIZATION. 1. REPORT DATE (DD-MM-YYYY)      30-06-2017 2

  2. Yeast derivatives and wheat germ in the adult diet modulates fecundity in a tephritid pest.

    Science.gov (United States)

    Goane, L; Pereyra, P M; Castro, F; Ruiz, M J; Juárez, M L; Segura, D F; Vera, M T

    2018-05-22

    Anastrepha fraterculus (Wiedemann), a pest of great economic importance in South America, needs urgently to be controlled by environmentally friendly methods such as the sterile insect technique for which mass rearing of insects is required. Because oogenesis takes place during the adult stage, mass-rearing facilities should provide the females a diet that maximizes egg production at the lowest cost. Accordingly, we investigated the effect of artificial protein sources in the adult diet (yeast derivatives of different cost but with similar amino acids profiles, and the addition of wheat germ) on fecundity. Additionally, we evaluated different ratios of yeast derivatives or wheat germ on ovary maturation, fecundity, and fertility as well as their association with the nutrient content of females. Females fed hydrolyzed yeast and yeast extract attained the highest fecundity level, and those fed brewer's yeast the lowest. Reducing the amount of hydrolyzed yeast, an expensive protein source, in the diet negatively affected fecundity and ovary maturation. Increasing the amount of brewer's yeast, a low-cost protein source, did not favor fecundity. The addition of wheat germ in the adult diet improved fecundity regardless of the yeast derivate considered. Percentage of egg hatch was not affected by the diet. Nutrient content of A. fraterculus females varied according to the adult diet provided and mating status. Our findings provide novel baseline information to understand the role of nutrition on reproductive performance of A. fraterculus females and are discussed in the context of resource allocation. They also provide valuable advances in the search for cost-effective adult diets at fruit fly mass rearing facilities.

  3. Artificial Intelligence: Is the Future Now for A.I.?

    Science.gov (United States)

    Ramaswami, Rama

    2009-01-01

    In education, artificial intelligence (AI) has not made much headway. In the one area where it would seem poised to lend the most benefit--assessment--the reliance on standardized tests, intensified by the demands of the No Child Left Behind Act of 2001, which holds schools accountable for whether students pass statewide exams, precludes its use.…

  4. Flying by Ear: Blind Flight with a Music-Based Artificial Horizon

    Science.gov (United States)

    Simpson, Brian D.; Brungart, Douglas S.; Dallman, Ronald C.; Yasky, Richard J., Jr.; Romigh, Griffin

    2008-01-01

    Two experiments were conducted in actual flight operations to evaluate an audio artificial horizon display that imposed aircraft attitude information on pilot-selected music. The first experiment examined a pilot's ability to identify, with vision obscured, a change in aircraft roll or pitch, with and without the audio artificial horizon display. The results suggest that the audio horizon display improves the accuracy of attitude identification overall, but differentially affects response time across conditions. In the second experiment, subject pilots performed recoveries from displaced aircraft attitudes using either standard visual instruments, or, with vision obscured, the audio artificial horizon display. The results suggest that subjects were able to maneuver the aircraft to within its safety envelope. Overall, pilots were able to benefit from the display, suggesting that such a display could help to improve overall safety in general aviation.

  5. The Silent Language of an Artificial Body

    Directory of Open Access Journals (Sweden)

    Alina Maria Hrisca

    2012-07-01

    Full Text Available This article presents some alterations of body language, due to the interventions in/on thebody. Body language has been theorized a lot in the last decades, and one of the most importantauthors we will refer to is Paul Ekman and his micro-expressions theory. Ekman tried to give auniversaldecoderof involuntary face reactions, and this is important now more than ever, becausemicro-expression are more and more diminished, due to the latest chemical and technicalinterventions in/on the body (especially the face.Using observation and some new works in thefields of both philosophy and sociology, we will analyze the effects on body-language of thesealterations ofthe body.Minimizing a lot the micro-gestures and face-expressions, as well as stressingthe functional aspect of an artificial body, body-language has a lot to suffer. It gets reduced andpeople begin toreadbodies only through their presence, not by their expressions. Standardization anda very simplified body-language and non-verbal cues are also consequences of an artificial body.Allof this makes body-language hard to express and at the same time hard todecode. This paper stressesthe effects thatan artificial body has on body-language, and also the importance of choosing a rightpath in the future interventions in/over the body.

  6. Experiments with microcomputer-based artificial intelligence environments

    Science.gov (United States)

    Summers, E.G.; MacDonald, R.A.

    1988-01-01

    The U.S. Geological Survey (USGS) has been experimenting with the use of relatively inexpensive microcomputers as artificial intelligence (AI) development environments. Several AI languages are available that perform fairly well on desk-top personal computers, as are low-to-medium cost expert system packages. Although performance of these systems is respectable, their speed and capacity limitations are questionable for serious earth science applications foreseen by the USGS. The most capable artificial intelligence applications currently are concentrated on what is known as the "artificial intelligence computer," and include Xerox D-series, Tektronix 4400 series, Symbolics 3600, VAX, LMI, and Texas Instruments Explorer. The artificial intelligence computer runs expert system shells and Lisp, Prolog, and Smalltalk programming languages. However, these AI environments are expensive. Recently, inexpensive 32-bit hardware has become available for the IBM/AT microcomputer. USGS has acquired and recently completed Beta-testing of the Gold Hill Systems 80386 Hummingboard, which runs Common Lisp on an IBM/AT microcomputer. Hummingboard appears to have the potential to overcome many of the speed/capacity limitations observed with AI-applications on standard personal computers. USGS is a Beta-test site for the Gold Hill Systems GoldWorks expert system. GoldWorks combines some high-end expert system shell capabilities in a medium-cost package. This shell is developed in Common Lisp, runs on the 80386 Hummingboard, and provides some expert system features formerly available only on AI-computers including frame and rule-based reasoning, on-line tutorial, multiple inheritance, and object-programming. ?? 1988 International Association for Mathematical Geology.

  7. Remineralization of artificial enamel lesions by theobromine.

    Science.gov (United States)

    Amaechi, B T; Porteous, N; Ramalingam, K; Mensinkai, P K; Ccahuana Vasquez, R A; Sadeghpour, A; Nakamoto, T

    2013-01-01

    This study investigated the remineralization potential of theobromine in comparison to a standard NaF dentifrice. Three tooth blocks were produced from each of 30 teeth. Caries-like lesion was created on each block using acidified gel. A smaller block was cut from each block for baseline scanning electron microscopy imaging and electron-dispersive spectroscopy (EDS) analysis for surface Ca level. A tooth slice was cut from each lesion-bearing block for transverse microradiography (TMR) quantification of baseline mineral loss (Δz) and lesion depth (LD). Then baseline surface microhardness (SMH) of each lesion was measured. The three blocks from each tooth were assigned to three remineralizing agents: (1) artificial saliva; (2) artificial saliva with theobromine (0.0011 mol/l), and (3) NaF toothpaste slurry (0.0789 mol/l F). Remineralization was conducted using a pH cycling model with storage in artificial saliva. After a 28-day cycle, samples were analyzed using EDS, TMR, and SMH. Intragroup comparison of pre- and posttest data was performed using t tests (p theobromine (38 ± 32%) and toothpaste (29 ± 16%). With TMR (Δz/lD), theobromine and toothpaste exhibited significantly (p theobromine and toothpaste was not significantly different. With EDS, calcium deposition was significant in all groups, but not significantly different among the groups (theobromine 13 ± 8%, toothpaste 10 ± 5%, and artificial saliva 6 ± 8%). The present study demonstrated that theobromine in an apatite-forming medium can enhance the remineralization potential of the medium. Copyright © 2013 S. Karger AG, Basel.

  8. High fat, low carbohydrate diet limit fear and aggression in Göttingen minipigs

    DEFF Research Database (Denmark)

    Haagensen, Annika Maria Juul; Sørensen, Dorte Bratbo; Sandøe, Peter

    2014-01-01

    High fat, low carbohydrate diets have become popular, as short-term studies show that such diets are effective for reducing body weight, and lowering the risk of diabetes and cardiovascular disease. There is growing evidence from both humans and other animals that diet affects behaviour and intake...... of fat has been linked, positively and negatively, with traits such as exploration, social interaction, anxiety and fear. Animal models with high translational value can help provide relevant and important information in elucidating potential effects of high fat, low carbohydrate diets on human behaviour....... Twenty four young, male Göttingen minipigs were fed either a high fat/cholesterol, low carbohydrate diet or a low fat, high carbohydrate/sucrose diet in contrast to a standard low fat, high carbohydrate minipig diet. Spontaneous behaviour was observed through video recordings of home pens and test...

  9. Generative Artificial Intelligence : Philosophy and Theory of Artificial Intelligence

    NARCIS (Netherlands)

    van der Zant, Tijn; Kouw, Matthijs; Schomaker, Lambertus; Mueller, Vincent C.

    2013-01-01

    The closed systems of contemporary Artificial Intelligence do not seem to lead to intelligent machines in the near future. What is needed are open-ended systems with non-linear properties in order to create interesting properties for the scaffolding of an artificial mind. Using post-structuralistic

  10. Is a healthy diet an environmentally sustainable diet?

    Science.gov (United States)

    Macdiarmid, Jennie I

    2013-02-01

    The concept of a healthy and environmentally sustainable diet is not new, but with increasing concern about future global food security and climate change there is a renewed interest in this topic. Dietary intakes in UK accounts for approximately 20-30% of total annual greenhouse gas emissions (GHGE), with the greatest contributions coming from high intakes of meat and dairy products. Dietary proposals to help mitigate climate change (i.e. reduce GHGE) have focused on reducing consumption of meat and dairy products, but this must be considered in the context of the whole diet, alongside any possible nutritional consequences for health. Bringing together health and environmental impact of the diet raises the question of whether a healthy diet can also be an environmentally sustainable diet. While recent research showed that it is possible to achieve a realistic diet that meets dietary requirement for health and has lower GHGE, it cannot be assumed that a healthy diet will always have lower GHGE. With different combinations of food it is possible to consume a diet that meets dietary requirements for health, but has high GHGE. It is important to understand what constitutes a sustainable diet, but this then needs to be communicated effectively to try and change well-established dietary intakes of the population. Studies show that understanding of sustainable diets is poor and there are many misconceptions (e.g. the overestimation of the protein requirements for a healthy diet), which could contribute to the barriers towards changing dietary intakes.

  11. Energy intake of rats fed a cafeteria diet.

    Science.gov (United States)

    Prats, E; Monfar, M; Castellà, J; Iglesias, R; Alemany, M

    1989-02-01

    The proportion of lipid, carbohydrate and protein energy self-selected by male and female rats from a cafeteria diet has been studied for a 48-day period (36-day in female rats). The diet consisted in 12 different items and was offered daily, in excess and under otherwise standard conditions, to rats--caged in groups of three--from weaning to adulthood. Groups of control animals were studied in parallel and compared with the cafeteria groups. Cafeteria diet fed groups of rats ingested more energy and lowered their metabolic efficiency with age. Male rats ate more than females and increased their body weight even after female practically stopped growing. There was a wide variation in the aliments consumed each day by the cafeteria-fed rats. However, the proportion of lipid, protein and carbohydrate the rats ate remained constant. Male rats ingested more lipid than females. Carbohydrate consumption was constant in control and cafeteria fed groups of rats independently of sex. Protein consumption was higher in cafeteria rats than in controls, but the differences were not so important as with liquid. Fiber content of the cafeteria diet was lower than that of the control diet. The cafeteria diet selected by the rats was, thus, hypercaloric and hyperlipidic, with practically the same amount of carbohydrate than the control diet, slightly hyperproteic and, nevertheless, remarkably constant in its composition with respect to time. Cafeteria rats had a higher water intake than controls. All these trends were maintained despite the observed changes in the animals' tastes and their differential consumption of the ailments of the diet.

  12. Use of a glucomannan polymer to reduce the effects of mycotoxin-contaminated diets in finishing pigs

    Directory of Open Access Journals (Sweden)

    G. Pulina

    2010-04-01

    Full Text Available The use of feed additives with mycotoxin adsorption capacity is a common strategy for controlling negative effects of mycotoxins in swine production systems. However, adsorbents that may results very effective under experimental conditions, i.e. when feed contamination level is rather high, do not necessarily retain their efficacy when tested under field conditions feed with generally low mycotoxin contamination. In this study, the effects of diets artificially contaminated with aflatoxin B1 or ochratoxin A on fattening performance and serum chemistry of fattening pigs are investigated. Moreover, the ability of a commercial glucomannan polymer (Gm polimer to reduce or eliminate the effects of the contaminated feeds is tested. Thirty heavy pigs (BW = 110±10.6 kg were fed 6 diets (n = 5 pigs/diet for 4 weeks until slaughtering. Diets were: control without toxin added (C; added with 0.02 ppm of aflatoxin B1 (AFB1; added with 0.05 ppm of ochratoxin A (OTA; other three diets as the previous but the addition of 2.0 g/kg of Gm polymer (C-GM, AFB1-GM, OTA-GM. Daily weight gain (ADG and Feed efficiency ratio (FE were measured every two weeks. Data were analyzed with a two-way ANOVA that included the fixed effect of diet, time and their interaction. After the first 2 weeks the ADG did not differ significantly between the diets, even if the ADG of AFB1 diet was about 20% lower than AFB1-Gm or C. In the last 2 weeks the ADG of AFB1 diet was significantly lover than the other diets (P<0.01 and was about one-half of the values reported for the same group in the first period. The contamination with ochratoxin A did not affect fattening performance of pigs during the whole experimental period. No damages were found in kidneys of all diets. Moreover, no evidence of association between observed liver damages and different diets was found. Finally, no differences between experimental diets were evidenced for the haematological parameters.

  13. Artificial life and Piaget.

    Science.gov (United States)

    Mueller, Ulrich; Grobman, K H.

    2003-04-01

    Artificial life provides important theoretical and methodological tools for the investigation of Piaget's developmental theory. This new method uses artificial neural networks to simulate living phenomena in a computer. A recent study by Parisi and Schlesinger suggests that artificial life might reinvigorate the Piagetian framework. We contrast artificial life with traditional cognitivist approaches, discuss the role of innateness in development, and examine the relation between physiological and psychological explanations of intelligent behaviour.

  14. High-fiber rye diet increases ileal excretion of energy and macronutrients compared with low-fiber wheat diet independent of meal frequency in ileostomy subjects

    DEFF Research Database (Denmark)

    Isaksson, Hanna; Landberg, Rikard; Sundberg, Birgitta

    2013-01-01

    -fiber diet compared to a refined wheat low-fiber diet was investigated. Furthermore, the effect of meal frequency on apparent absorption of nutrients was studied for the first time. Design: Ten participants that had undergone ileostomy consumed standardized iso-caloric diets, including low-fiber wheat bread...... (20 g dietary fiber per day) for 2 weeks followed by high-fiber rye bread (52 g dietary fiber per day) for 2 weeks. The diets were consumed in an ordinary (three meals per day) and a nibbling (seven meals per day) meal frequency in a cross-over design. Ileal effluents were collected during 24 h...... was independent of meal frequency. This suggests that a high intake of rye may result in lower availability of macronutrients for small intestinal digestion and absorption. A regular intake of rye may therefore have implications for weight management....

  15. Diet and dietary habits of the fish Schilbe mystus (Siluriformes: Schilbeidae in two artificial lakes in Southwestern Nigeria

    Directory of Open Access Journals (Sweden)

    Adedolapo Ayoade

    2008-12-01

    Full Text Available Diet and dietary habits of African Butter Catfish Schilbe mystus (Linne, 1766, an economically important fish in Oyan and Asejire lakes (Southwest Nigeria were examined between July 2000 and December 2001. Stomach contents were analysed using the numerical, frequency of occurrence and points methods. The fish is predatory but the diet differs among lakes and seasons. Insects were more important in the diet of small (La dieta y los hábitos alimenticios de Schilbe mystus (Linne, 1766, un pez de importancia comercial en los lagos de Oyan y Asejire (Nigeria, fueron examinados desde diciembre del 2000 a diciembre del 2001. Se realizaron análisis de contenido estomacal utilizando métodos numéricos, de frecuencia de presencia y puntuales. Existe variación estacional en los organismos seleccionados para alimento y los insectos son más importantes para peces pequeños (<18 cm. También hay diferencias en la cantidad de alimento encontrado en los estómagos de machos con respecto a las hembras de S. mystus en ambos hábitats. El patrón de selección y consumo de alimento en estas especies es distinto en los dos lagos.

  16. Artificial sweeteners

    DEFF Research Database (Denmark)

    Raben, Anne Birgitte; Richelsen, Bjørn

    2012-01-01

    Artificial sweeteners can be a helpful tool to reduce energy intake and body weight and thereby risk for diabetes and cardiovascular diseases (CVD). Considering the prevailing diabesity (obesity and diabetes) epidemic, this can, therefore, be an important alternative to natural, calorie-containin......Artificial sweeteners can be a helpful tool to reduce energy intake and body weight and thereby risk for diabetes and cardiovascular diseases (CVD). Considering the prevailing diabesity (obesity and diabetes) epidemic, this can, therefore, be an important alternative to natural, calorie......-containing sweeteners. The purpose of this review is to summarize the current evidence on the effect of artificial sweeteners on body weight, appetite, and risk markers for diabetes and CVD in humans....

  17. Artificial cognition architectures

    CERN Document Server

    Crowder, James A; Friess, Shelli A

    2013-01-01

    The goal of this book is to establish the foundation, principles, theory, and concepts that are the backbone of real, autonomous Artificial Intelligence. Presented here are some basic human intelligence concepts framed for Artificial Intelligence systems. These include concepts like Metacognition and Metamemory, along with architectural constructs for Artificial Intelligence versions of human brain functions like the prefrontal cortex. Also presented are possible hardware and software architectures that lend themselves to learning, reasoning, and self-evolution

  18. Removal of artificial dental calculus by use of conventional and diamond ultrasound tips.

    Directory of Open Access Journals (Sweden)

    Roberto Carlos Mourão Pinho

    2017-04-01

    Full Text Available Introduction: Periodontal disease is considered a public health problem and may lead to serious complications as the general health of patient. The main therapeutic procedure is scaling and root planing, which can be performed by a variety of techniques and instruments Objective:The aim of the present study was to evaluate the removal of calculus, produced artificially, by using a conventional ultrasonic tip and a diamond – CVD tip. Method: The calculus was produced with artificial sawdust and glue-based cyanoacrylate and distributed in twenty areas also standardized on two plates of acrylic resin (chemical activated, holding 10 samples per plate. Standards / samples were divided by lot into two simple groups, being A (treated with conventional tip and B (treated with CVD tip. Results:The treatment in Group A, promoted an average area of 20.48 ± 4.20 mm2 free of artificial calculus which is significantly higher (p <0.05 than the area removed in Group B (15.37 ± 5.29 mm2. Conclusion:The results showed that the conventional tip presented higher results than CVD tip for efficacy in the removal of calculus.

  19. Odor and odorous compound emissions from manure of swine fed standard and dried distillers grains with soluble (DDGS) supplemented diets

    Science.gov (United States)

    This study was conducted to determine the impact diets containing dried distillers grains with soluble (DDGS) have on emissions of odor and odorous compounds from swine manure storage. Twenty-four pigs were fed either a corn-soybean meal (CSBM) diet or a CSBM diet containing 35% DDGS. Pigs were fed ...

  20. Liver phospholipids fatty acids composition in response to different types of diets in rats of both sexes.

    Science.gov (United States)

    Ranković, Slavica; Popović, Tamara; Martačić, Jasmina Debeljak; Petrović, Snježana; Tomić, Mirko; Ignjatović, Đurđica; Tovilović-Kovačević, Gordana; Glibetić, Maria

    2017-05-19

    Dietary intake influence changes in fatty acids (FA) profiles in liver which plays a central role in fatty acid metabolism, triacylglycerol synthesis and energy homeostasis. We investigated the effects of 4-weeks treatment with milk- and fish-based diet, on plasma biochemical parameters and FA composition of liver phospholipids (PL) in rats of both sexes. Adult, 4 months old, Wistar rats of both sexes, were fed with different types of diets: standard, milk-based and fish-based, during 4 weeks. Analytical characterization of different foods was done. Biochemical parameters in plasma were determined. Fatty acid composition was analyzed by gas-chromatography. Statistical significance of FA levels was tested with two-way analysis of variance (ANOVA) using the sex of animals and treatment (type of diet) as factors on logarithmic or trigonometric transformed data. Our results showed that both, milk- and fish-based diet, changed the composition and ratio of rat liver phospholipids FA, in gender-specific manner. Initially present sex differences appear to be dietary modulated. Although, applied diets changed the ratio of total saturated fatty acids (SFA), monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA), and effects were gender specific. Milk-based diet lowered SFA and elevated MUFA in males and increased PUFA in females vs. standard diet. The same diet decreased n-3, increased n-6 and n-6/n-3 ratio in males. Fish-based diet increased n-3, decreased n-6 and n-6/n-3 ratio vs. standard and milk-based diet in females. However, the ratio of individual FA in liver PL was also dietary-influenced, but with gender specific manner. While in females fish-based diet decreased AA (arachidonic acid) increased level of EPA (eicosapentaenoic acid), DPA (docosapentaenoic acid) and DHA (docosahexaenoic acid), the same diet elevated only DHA levels in males. Gender related variations in FA composition of rat liver PL were observed, and results have shown that

  1. Diet supplementation with açaí (Euterpe oleracea Mart.) pulp improves biomarkers of oxidative stress and the serum lipid profile in rats.

    OpenAIRE

    Souza, Melina Oliveira de; Silva, Maísa; Silva, Marcelo Eustáquio; Oliveira, Riva de Paula; Pedrosa, Maria Lúcia

    2010-01-01

    Objective: We investigated the antioxidant potential and hypocholesterolemic effects of acai (Euterpe oleracea Mart.) pulp ingestion in rats fed a standard or hypercholesterolemic diet. Methods: Female Fischer rats were fed a standard AIN-93 M diet (control) or a hypercholesterolemic diet that contained 25% soy oil and 1% cholesterol. The test diet was supplemented with 2% acai pulp (dry wt/wt) for control (group CA) and hypercholesterolemic rats (group HA) for 6 wk. At the end of the experim...

  2. Challenges in introduction of artificial intelligence in medical practice – a review of clinical trials concerning adaptation of artificial intelligence in medicine

    OpenAIRE

    Mielnik, Pawel Franciszek; Fojcik, Marcin; Kulbacki, Marek; Segen, Jakub

    2016-01-01

    An interest in Artificial Intelligence [AI] as science is growing in the last years. It has become gradually more used in the medicine. Methodology of development and testing of AI algorithms is generally well established. Use of AI in medicine requires elaboration of standards of its validation in clinical settings. This paper is a review of literature concerning clinical trials on AI adaptation in medicine

  3. Recurrent Artificial Neural Networks and Finite State Natural Language Processing.

    Science.gov (United States)

    Moisl, Hermann

    It is argued that pessimistic assessments of the adequacy of artificial neural networks (ANNs) for natural language processing (NLP) on the grounds that they have a finite state architecture are unjustified, and that their adequacy in this regard is an empirical issue. First, arguments that counter standard objections to finite state NLP on the…

  4. Simple artificial training device for respiratory muscle strength and lung volumes in healthy young male and female subjects: A pilot study.

    Science.gov (United States)

    Leelarungrayub, Jirakrit; Pinkaew, Decha; Yankai, Araya; Chautrakoon, Busaba; Kuntain, Rungtiwa

    2017-10-01

    The aim of this study was to evaluate the efficiency of a simple artificial device for respiratory muscle strength training and lung volumes using either combined or non-combined exercise with elastic bands in healthy young participants. Forty healthy young participants (20 male and 20 female) aged 19-24 years old were randomized into two main experiments with four sub-groups; (1) artificial device (n = 10) & standard device (n = 10) training, and (2) artificial device training combined with elastic band (EB) exercise (n = 10) & standard device training combined with EB (n = 10) exercise. Respiratory muscle strength with maximal peak inspiratory pressure (PImax), and lung volumes; tidal volume (TV), inspiratory reserve volume (IRV), expiratory reserve volume (ERV) and vital capacity (VC) were evaluated before and after training once daily for 3 weeks. Moreover, the peak dyspnea score and vital sign parameters were compared between the experimental groups after final training. All parameters had no statistical differences (p > 0.5) between the training devices alone and those combined with EB exercise prior to any experiments. Results from the first experiment showed that training with an artificial device increased all parameters (PImax, VC, IRV, ERV) significantly (p artificial device training combined with EB exercise showed a significant increase in all parameters, except for TV, and they were the same as the increased results in training with the standard device combined with EB exercise. There was no significant difference of data between these groups after the training period. Finally, the results of peak dyspnea score and all vital sign parameters from using the artificial device, with or without EB exercise, showed no statistical difference when compared to use of the standard device. This study proposed that a simple artificial device can be used to train the respiratory muscle with or without elastic band exercise in healthy young subjects

  5. Application of artificial neural networks to determine the authentication of fattening diets of Iberian pigs according to their triacylglycerol profiles

    Directory of Open Access Journals (Sweden)

    León-Camacho, M.

    2013-04-01

    Full Text Available The triacylglycerols in the subcutaneous fat from Iberian pigs reared on four different feeding types, Montanera, Recebo, extensive Cebo and intensive Cebo, have been determined by gas chromatography with a flame ionization detector. Analyses were performed in a column coated with a bonded stationary phase (50% phenyl-50% methylpolysiloxane with hydrogen as the carrier gas. Lipids were extracted by melting the subcutaneous fat in a microwave oven and then filtering and dissolving it in hexane. A total amount of 2783 samples from several campaigns were considered. Using the triacylglycerols as chemical descriptors, a study on the discriminating power to differentiate samples according to the pig feeding type and system was performed. With this aim, pattern recognition techniques, such as linear discriminant analysis (LDA and multilayer perceptron artificial neural networks (MLPANN, have been used. ANN performed better than LDA, with a mean prediction ability of approximately 97% in the differentiation of fattening diets such as Montanera, extensive Cebo and intensive Cebo. In the case of including the recebo fattening diet, the model presents a mean performance of 82%. The differentiation of fattening systems has also been achieved by means of ANN, with a mean performance of 96%.Se ha determinado mediante cromatografía de gases con detector de ionización de llama los triglicéridos de la grasa subcutánea de cerdos ibéricos, cebados con cuatro tipos de alimentación: montanera, recebo, cebo extensivo y cebo intensivo. Los análisis se realizaron en una columna con una fase estacionaria ligada químicamente (50% fenil-50% metilpolisiloxano usando hidrógeno como gas portador. La grasa subcutánea se extrajo por fusión en horno de microondas, posteriormente se filtró y se disolvió en hexano. Un total de 2.783 muestras de varias campañas fueron analizadas. Usando los triglicéridos como descriptores químicos se ha llevado a cabo un estudio

  6. [Research progress on mechanical performance evaluation of artificial intervertebral disc].

    Science.gov (United States)

    Li, Rui; Wang, Song; Liao, Zhenhua; Liu, Weiqiang

    2018-03-01

    The mechanical properties of artificial intervertebral disc (AID) are related to long-term reliability of prosthesis. There are three testing methods involved in the mechanical performance evaluation of AID based on different tools: the testing method using mechanical simulator, in vitro specimen testing method and finite element analysis method. In this study, the testing standard, testing equipment and materials of AID were firstly introduced. Then, the present status of AID static mechanical properties test (static axial compression, static axial compression-shear), dynamic mechanical properties test (dynamic axial compression, dynamic axial compression-shear), creep and stress relaxation test, device pushout test, core pushout test, subsidence test, etc. were focused on. The experimental techniques using in vitro specimen testing method and testing results of available artificial discs were summarized. The experimental methods and research status of finite element analysis were also summarized. Finally, the research trends of AID mechanical performance evaluation were forecasted. The simulator, load, dynamic cycle, motion mode, specimen and test standard would be important research fields in the future.

  7. Artificial Disc Replacement

    Science.gov (United States)

    ... Spondylolisthesis BLOG FIND A SPECIALIST Treatments Artificial Disc Replacement (ADR) Patient Education Committee Jamie Baisden The disc ... Disc An artificial disc (also called a disc replacement, disc prosthesis or spine arthroplasty device) is a ...

  8. Diet-induced thermogenesis is lower in rats fed a lard diet than in those fed a high oleic acid safflower oil diet, a safflower oil diet or a linseed oil diet.

    Science.gov (United States)

    Takeuchi, H; Matsuo, T; Tokuyama, K; Shimomura, Y; Suzuki, M

    1995-04-01

    The objectives of the present study were to examine the effects of dietary fats differing in fatty acid composition on diet-induced thermogenesis, sympathetic activity in brown adipose tissue and body fat accumulation in rats. Rats were meal-fed for 12 wk an isoenergetic diet based on lard, high oleic acid safflower oil, safflower oil or linseed oil, and norepinephrine turnover rates in brown adipose tissue were then estimated. Whole-body oxygen consumption after the meal indicated that diet-induced thermogenesis was significantly lower in rats fed the lard diet than in those fed the other diets. The norepinephrine turnover rate in the interscapular brown adipose tissue was also significantly lower in the lard diet group than in the other diet groups. The carcass fat content was significantly higher in the lard diet group than in the other diet groups, whereas the abdominal adipose tissue weights were the same in all diet groups. These results suggest that the intake of animal fats rich in saturated fatty acids, compared with the intake of vegetable oils rich in monounsaturated or polyunsaturated fatty acids, decreases diet-induced thermogenesis by a decline of sympathetic activity in brown adipose tissue, resulting in the promotion of body fat accumulation.

  9. Diet as prophylaxis and treatment for venous thromboembolism?

    Directory of Open Access Journals (Sweden)

    Cundiff David K

    2010-08-01

    Full Text Available Abstract Background Both prophylaxis and treatment of venous thromboembolism (VTE: deep venous thrombosis (DVT and pulmonary emboli (PE with anticoagulants are associated with significant risks of major and fatal hemorrhage. Anticoagulation treatment of VTE has been the standard of care in the USA since before 1962 when the U.S. Food and Drug Administration began requiring randomized controlled clinical trials (RCTs showing efficacy, so efficacy trials were never required for FDA approval. In clinical trials of 'high VTE risk' surgical patients before the 1980s, anticoagulant prophylaxis was clearly beneficial (fatal pulmonary emboli (FPE without anticoagulants = 0.99%, FPE with anticoagulants = 0.31%. However, observational studies and RCTs of 'high VTE risk' surgical patients from the 1980s until 2010 show that FPE deaths without anticoagulants are about one-fourth the rate that occurs during prophylaxis with anticoagulants (FPE without anticoagulants = 0.023%, FPE while receiving anticoagulant prophylaxis = 0.10%. Additionally, an FPE rate of about 0.012% (35/28,400 in patients receiving prophylactic anticoagulants can be attributed to 'rebound hypercoagulation' in the two months after stopping anticoagulants. Alternatives to anticoagulant prophylaxis should be explored. Methods and Findings The literature concerning dietary influences on VTE incidence was reviewed. Hypotheses concerning the etiology of VTE were critiqued in relationship to the rationale for dietary versus anticoagulant approaches to prophylaxis and treatment. Epidemiological evidence suggests that a diet with ample fruits and vegetables and little meat may substantially reduce the risk of VTE; vegetarian, vegan, or Mediterranean diets favorably affect serum markers of hemostasis and inflammation. The valve cusp hypoxia hypothesis of DVT/VTE etiology is consistent with the development of VTE being affected directly or indirectly by diet. However, it is less consistent with

  10. Artificial Stroke Clots: How Wide is the Gap to the Real World?

    Science.gov (United States)

    Berndt, Maria; Prothmann, Sascha; Maegerlein, Christian; Oberdieck, Paul; Zimmer, Claus; Hegge, Barbara; Pelisek, Jaroslav; Schirmer, Lucas; Poppert, Holger; Boeckh-Behrens, Tobias

    2018-02-01

    Especially since the establishment of mechanical thrombectomy as part of standard stroke therapy, artificial thrombi have become important in the training of interventionalists as well as for the development and testing of devices. So far, these in vitro clots have lacked direct comparisons with ex vivo thrombi. We therefore compared the histologic appearance of dynamically produced clots with that of stroke thrombi acquired during mechanical recanalization. Thrombi of 145 consecutive patients with stroke with large-vessel occlusions were histologically compared with 10 artificial clots, dynamically created from human blood and pig's blood using a Chandler loop system. Quantified FP/RBC ratios (fibrin/platelets divided by red blood cell fraction) and white blood cell (WBC) fractions were identified and compared between artificial (human and pig) and ex vivo thrombi obtained from patients with various stroke causes. There were no significant differences in the analysis of FP/RBC ratios between artificial thrombi and ex vivo thrombi (P = 0.42) or in the more precise analyses considering etiologic subgroups. Distinct differences were observed for the WBC fraction, with lower values in artificial thrombi (median, 1.34%) than in ex vivo thrombi (median, 5%) (P < 0.001). The main clot components, FP and RBC, are presumably the most influential factors for clot stability and mechanical resistance. Similarities between artificially generated and ex vivo stroke clots (and when considering different stroke subgroups) support the usefulness of these artificial thrombi in the pre-evaluation of thrombus extraction devices and as appropriate training material. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Is the Chilean Diet a Mediterranean-type Diet?

    Directory of Open Access Journals (Sweden)

    JAIME ROZOWSKI

    2004-01-01

    Full Text Available Food intake in Chile has changed markedly in the last decades, showing an increase in fat consumption and presently a small fruit and vegetables intake. A parallel is made between the Chilean and Mediterranean diet (mainly the one from Spain, Italy, and Greece, both currently and from 50 years ago. The main differences and similarities are based on food availability. Although Chilean diet seems to be approaching the traditional Mediterranean diet of the 60's, there is concern about changes that are moving away from Chilean traditional diet and towards a western one. A new food pyramid for Chile is proposed based on the traditional Mediterranean-type diet

  12. Response of broiler chickens to diets containing artificially dried high-moisture maize supplemented with microbial enzymes

    OpenAIRE

    Bhuiyan, M.M; Islam, A.F; Iji, P.A

    2010-01-01

    The effect of feeding high-moisture maize grains dried in the sun or artificially in a forced draught oven at 80, 90 or 100 ºC for 24 hours and supplemented with microbial enzymes (Avizyme 1502 and Phyzyme XP) on growth performance, visceral organs, tissue protein, enzyme activity and gut development was investigated in a broiler growth trial. Feed intake (FI) up to 21 days decreased as a results of oven drying of grains whereas supplementation with microbial enzymes increased FI compared to ...

  13. Techniques of artificial intelligence applied to the electric power expansion distribution system planning problem; Tecnicas de inteligencia artificial aplicadas ao problema de planejamento da expansao do sistema de distribuicao de energia eletrica

    Energy Technology Data Exchange (ETDEWEB)

    Froes, Salete Maria

    1996-07-01

    A tool named Constrained Decision Problem (CDP), which is based on Artificial Intelligence and a specific application to Distribution System Planning is described. The CDP allows multiple objective optimization that does not, necessarily, result in a single optimal solution. First, a literature review covers published works related to Artificial Intelligence applications to Electric Power Distribution Systems, emphasizing feeder restoration and reconfiguration. Some concepts related to Artificial Intelligence are described, with particular attention to Planning and to Constrained Decision Problems. Following, an Electric Power System planning model is addressed by using the CDP tool. Some case studies illustrate the Distribution Planning model, which are compared with standard optimization models. Concluding, some comments establishing the possibilities of CDP applications are followed by a view on future developments. (author)

  14. Artificial life and life artificialization in Tron

    Directory of Open Access Journals (Sweden)

    Carolina Dantas Figueiredo

    2012-12-01

    Full Text Available Cinema constantly shows the struggle between the men and artificial intelligences. Fiction, and more specifically fiction films, lends itself to explore possibilities asking “what if?”. “What if”, in this case, is related to the eventual rebellion of artificial intelligences, theme explored in the movies Tron (1982 and Tron Legacy (2010 trat portray the conflict between programs and users. The present paper examines these films, observing particularly the possibility programs empowering. Finally, is briefly mentioned the concept of cyborg as a possibility of response to human concerns.

  15. Research review: the role of diet in the treatment of attention-deficit/hyperactivity disorder--an appraisal of the evidence on efficacy and recommendations on the design of future studies

    NARCIS (Netherlands)

    Stevenson, J.; Buitelaar, J.K.; Cortese, S.; Ferrin, M.; Konofal, E.; Lecendreux, M.; Simonoff, E.; Wong, I.C.; Sonuga-Barke, E.

    2014-01-01

    BACKGROUND: The efficacy of three dietary treatments for ADHD has been repeatedly tested in randomized controlled trials (RCTs). These interventions are restricted elimination diets (RED), artificial food colour elimination (AFCE) and supplementation with free fatty acids (SFFA). There have been

  16. The Impact of Diet Protein and Carbohydrate on Select Life-History Traits of The Black Soldier Fly Hermetia illucens (L.) (Diptera: Stratiomyidae).

    Science.gov (United States)

    Cammack, Jonathan A; Tomberlin, Jeffery K

    2017-05-31

    This study examined the impact of diet protein and carbohydrate percentages as well as moisture on the immature development, survivorship, and resulting adult longevity and egg production of the black soldier fly, Hermetia illucens (L.) (Diptera: Stratiomyidae). Moisture impacted development and corresponding life-history traits more than protein:carbohydrate content; larvae were unable to develop on diets at 40% moisture. Larvae fed diets at 70% moisture developed faster, grew larger, and required less food than those reared on diets at 55% moisture. Larvae reared on the balanced diet (21% protein:21% carbohydrate) at 70% moisture developed the fastest on the least amount of food and had the greatest survivorship to the prepupal stage. Adult emergence and longevity were similar across treatments, indicating immature life-history traits were impacted the most. The control (Gainesville house fly) diet was superior to the artificial diets for all parameters tested. These differences could indicate that other constituents (e.g., associated microbes) serve a role in black soldier fly development. These data are valuable for industrialization of this insect as a "green" technology for recycling organic waste, which can be highly variable, to produce protein for use as feed in the livestock, poultry, and aquaculture industries, as well as for bioenergy production.

  17. Med Diet 4.0: the Mediterranean diet with four sustainable benefits.

    Science.gov (United States)

    Dernini, S; Berry, E M; Serra-Majem, L; La Vecchia, C; Capone, R; Medina, F X; Aranceta-Bartrina, J; Belahsen, R; Burlingame, B; Calabrese, G; Corella, D; Donini, L M; Lairon, D; Meybeck, A; Pekcan, A G; Piscopo, S; Yngve, A; Trichopoulou, A

    2017-05-01

    To characterize the multiple dimensions and benefits of the Mediterranean diet as a sustainable diet, in order to revitalize this intangible food heritage at the country level; and to develop a multidimensional framework - the Med Diet 4.0 - in which four sustainability benefits of the Mediterranean diet are presented in parallel: major health and nutrition benefits, low environmental impacts and richness in biodiversity, high sociocultural food values, and positive local economic returns. A narrative review was applied at the country level to highlight the multiple sustainable benefits of the Mediterranean diet into a single multidimensional framework: the Med Diet 4.0. Setting/subjects We included studies published in English in peer-reviewed journals that contained data on the characterization of sustainable diets and of the Mediterranean diet. The methodological framework approach was finalized through a series of meetings, workshops and conferences where the framework was presented, discussed and ultimately refined. The Med Diet 4.0 provides a conceptual multidimensional framework to characterize the Mediterranean diet as a sustainable diet model, by applying principles of sustainability to the Mediterranean diet. By providing a broader understanding of the many sustainable benefits of the Mediterranean diet, the Med Diet 4.0 can contribute to the revitalization of the Mediterranean diet by improving its current perception not only as a healthy diet but also a sustainable lifestyle model, with country-specific and culturally appropriate variations. It also takes into account the identity and diversity of food cultures and systems, expressed within the notion of the Mediterranean diet, across the Mediterranean region and in other parts of the world. Further multidisciplinary studies are needed for the assessment of the sustainability of the Mediterranean diet to include these new dimensions.

  18. Sodium in diet

    Science.gov (United States)

    Diet - sodium (salt); Hyponatremia - sodium in diet; Hypernatremia - sodium in diet; Heart failure - sodium in diet ... Too much sodium in the diet may lead to: High blood pressure in some people A serious buildup of fluid in people with heart failure , cirrhosis of ...

  19. Evidence of changes in alpha-1/AT1 receptor function generated by diet-induced obesity.

    Science.gov (United States)

    Juarez, Esther; Tufiño, Cecilia; Querejeta, Enrique; Bracho-Valdes, Ismael; Bobadilla-Lugo, Rosa A

    2017-11-01

    To study whether hypercaloric diet-induced obesity deteriorates vascular contractility of rat aorta through functional changes in α 1 adrenergic and/or AT1 Angiotensin II receptors. Angiotensin II- or phenylephrine-induced contraction was tested on isolated aorta rings with and without endothelium from female Wistar rats fed for 7 weeks with hypercaloric diet or standard diet. Vascular expression of Angiotensin II Receptor type 1 (AT1R), Angiotensin II Receptor type 2 (AT2R), Cyclooxygenase-1 (COX-1), Cyclooxygenase-2 (COX-2), inducible Nitric Oxide Synthase (iNOS) and endothelial Nitric Oxide Synthase (eNOS), as well as blood pressure, glucose, insulin and angiotensin II blood levels were measured. Diet-induced obesity did not significantly change agonist-induced contractions (Emax and pD 2 hypercaloric diet vs standard diet n.s.d.) of both intact (e+) or endothelium free (e-) vessels but significantly decrease both phenylephrine and angiotensin II contraction (Emax p obesity did not change angiotensin II AT1, AT2 receptor proteins expression but reduced COX-1 and NOS2 ( p obesity produces alterations in vascular adrenergic and angiotensin II receptor dynamics that suggest an endothelium-dependent adrenergic/angiotensin II crosstalk. These changes reflect early-stage vascular responses to obesity.

  20. Effects of cocoa-enriched diet on orofacial pain in a murine model.

    Science.gov (United States)

    Bowden, L N; Rohrs, E L; Omoto, K; Durham, P L; Holliday, L S; Morris, A D; Allen, K D; Caudle, R M; Neubert, J K

    2017-06-01

    To investigate and discuss the effects of cocoa on orofacial pain. The Department of Orthodontics at the University of Florida (UF). Male and female hairless rats (N=20/group) were tested. Rats were tested using the Orofacial Pain Assessment Device (OPAD) before and after changing their food from the standard chow to a cocoa-enriched or control-equivalent diet. Male rats fed the cocoa diet had a significantly higher operant pain index when tested at 37°C as compared to control diet-fed animals. Female rats on the cocoa diet had a significantly higher pain index when tested at 18°C and 44°C, as compared to animals fed the control diet. Capsaicin-induced pain was inhibited, with cocoa-diet male rats having a significantly higher pain index than control-diet male rats and cocoa-diet female rats at both 37°C and 44°C. Cocoa-diet female rats had a significantly higher pain index at 44°C than control-diet females. Mechanical sensitivity was affected following capsaicin cream, with a significantly decreased tolerated bottle distance in both cocoa- and control-diet animals, but there was no difference between cocoa- and control-diet groups. Using the OPAD operant system, we demonstrated that a diet rich in cocoa was effective in inhibiting neurogenic inflammatory pain in rats. This has implications for the use of novel alternative therapies such as diet modification for pain control. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Mediterranean diet

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000110.htm Mediterranean diet To use the sharing features on this page, ... and other health problems. How to Follow the Diet The Mediterranean diet is based on: Plant-based ...

  2. Low-carbohydrate diet induces metabolic depression: a possible mechanism to conserve glycogen.

    Science.gov (United States)

    Winwood-Smith, Hugh S; Franklin, Craig E; White, Craig R

    2017-10-01

    Long-term studies have found that low-carbohydrate diets are more effective for weight loss than calorie-restricted diets in the short term but equally or only marginally more effective in the long term. Low-carbohydrate diets have been linked to reduced glycogen stores and increased feelings of fatigue. We propose that reduced physical activity in response to lowered glycogen explains the diminishing weight loss advantage of low-carbohydrate compared with low-calorie diets over longer time periods. We explored this possibility by feeding adult Drosophila melanogaster a standard or a low-carbohydrate diet for 9 days and measured changes in metabolic rate, glycogen stores, activity, and body mass. We hypothesized that a low-carbohydrate diet would cause a reduction in glycogen stores, which recover over time, a reduction in physical activity, and an increase in resting metabolic rate. The low-carbohydrate diet reduced glycogen stores, which recovered over time. Activity was unaffected by diet, but metabolic rate was reduced, in the low-carbohydrate group. We conclude that metabolic depression could explain the decreased effectiveness of low-carbohydrate diets over time and recommend further investigation of long-term metabolic effects of dietary interventions and a greater focus on physiological plasticity within the study of human nutrition. Copyright © 2017 the American Physiological Society.

  3. Vildagliptin Can Alleviate Endoplasmic Reticulum Stress in the Liver Induced by a High Fat Diet

    OpenAIRE

    Ma, Xiaoqing; Du, Wenhua; Shao, Shanshan; Yu, Chunxiao; Zhou, Lingyan; Jing, Fei

    2018-01-01

    Purpose. We investigated whether a DDP-4 inhibitor, vildagliptin, alleviated ER stress induced by a high fat diet and improved hepatic lipid deposition. Methods. C57BL/6 mice received standard chow diet (CD), high fat diet (HFD), and HFD administered with vildagliptin (50 mg/Kg) (V-HFD). After administration for 12 weeks, serum alanine aminotransferase, glucose, cholesterol, triglyceride, and insulin levels were analyzed. Samples of liver underwent histological examination and transmission el...

  4. Effects of Persian leek (Allium ampeloprasum) on hepatic lipids and the expression of proinflammatory gene in hamsters fed a high-fat/ high-cholesterol diet.

    Science.gov (United States)

    Fatoorechi, Vahideh; Rismanchi, Marjan; Nasrollahzadeh, Javad

    2016-01-01

    Persian leek is one of the most widely used herbal foods among Iranians. In this study, effects of oral administration of Persian leek on plasma and liver lipids were examined in hamster. Male Syrian hamsters were randomly divided into three groups: control (standard diet), high fat control (high-fat/high-cholesterol diet), Persian leek (high-fat/high-cholesterol diet + 1% per weight of diet from dried powdered Persian leek) for 14 weeks. High fat diet increased plasma and liver lipids as compared to standard diet. Adding Persian leek to the high-fat/high-cholesterol diet resulted in no significant changes in the concentration of the plasma lipids or liver cholesterol. However, liver triglycerides (TG), plasma Alanine aminotransferase and gene expression of tumor necrosis factor- α were decreased in hamsters fed high-fat diet containing Persian leek as compared to high-fat diet only. Persian leek might be considered as a herbal food that can reduce liver TG accumulation induced by high fat diets.

  5. Development of hepatocellular cancer induced by long term low fat-high carbohydrate diet in a NAFLD/NASH mouse model.

    Science.gov (United States)

    Tessitore, Alessandra; Mastroiaco, Valentina; Vetuschi, Antonella; Sferra, Roberta; Pompili, Simona; Cicciarelli, Germana; Barnabei, Remo; Capece, Daria; Zazzeroni, Francesca; Capalbo, Carlo; Alesse, Edoardo

    2017-08-08

    Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease. It can progress to nonalcoholic steatohepatitis (NASH) and, in a percentage of cases, to hepatocarcinogenesis. The strong incidence in western countries of obesity and metabolic syndrome, whose NAFLD is the hepatic expression, is thought to be correlated to consumption of diets characterized by processed food and sweet beverages. Previous studies described high-fat diet-induced liver tumors. Conversely, the involvement of low-fat/high-carbohydrate diet in the progression of liver disease or cancer initiation has not been described yet. Here we show for the first time hepatic cancer formation in low-fat/high-carbohydrate diet fed NAFLD/NASH mouse model. Animals were long term high-fat, low-fat/high-carbohydrate or standard diet fed. We observed progressive liver damage in low-fat/high-carbohydrate and high-fat animals after 12 and, more, 18 months. Tumors were detected in 20% and 50% of high-fat diet fed mice after 12 and 18 months and, interestingly, in 30% of low-fat/high-carbohydrate fed animals after 18 months. No tumors were detected in standard diet fed mice. Global increase of hepatic interleukin-1β, interleukin-6, tumor necrosis factor-α and hepatocyte growth factor was detected in low-fat/high-carbohydrate and high-fat with respect to standard diet fed mice as well as in tumor with respect to non-tumor bearing mice. A panel of 15 microRNAs was analyzed: some of them revealed differential expression in low-fat/high-carbohydrate with respect to high-fat diet fed groups and in tumors. Data here shown provide the first evidence of the involvement of low-fat/high-carbohydrate diet in hepatic damage leading to tumorigenesis.

  6. Diet induced thermogenesis

    Directory of Open Access Journals (Sweden)

    Westerterp KR

    2004-08-01

    Full Text Available Objective Daily energy expenditure consists of three components: basal metabolic rate, diet-induced thermogenesis and the energy cost of physical activity. Here, data on diet-induced thermogenesis are reviewed in relation to measuring conditions and characteristics of the diet. Methods Measuring conditions include nutritional status of the subject, physical activity and duration of the observation. Diet characteristics are energy content and macronutrient composition. Results Most studies measure diet-induced thermogenesis as the increase in energy expenditure above basal metabolic rate. Generally, the hierarchy in macronutrient oxidation in the postprandial state is reflected similarly in diet-induced thermogenesis, with the sequence alcohol, protein, carbohydrate, and fat. A mixed diet consumed at energy balance results in a diet induced energy expenditure of 5 to 15 % of daily energy expenditure. Values are higher at a relatively high protein and alcohol consumption and lower at a high fat consumption. Protein induced thermogenesis has an important effect on satiety. In conclusion, the main determinants of diet-induced thermogenesis are the energy content and the protein- and alcohol fraction of the diet. Protein plays a key role in body weight regulation through satiety related to diet-induced thermogenesis.

  7. [Total artificial heart].

    Science.gov (United States)

    Antretter, H; Dumfarth, J; Höfer, D

    2015-09-01

    To date the CardioWest™ total artificial heart is the only clinically available implantable biventricular mechanical replacement for irreversible cardiac failure. This article presents the indications, contraindications, implantation procedere and postoperative treatment. In addition to a overview of the applications of the total artificial heart this article gives a brief presentation of the two patients treated in our department with the CardioWest™. The clinical course, postoperative rehabilitation, device-related complications and control mechanisms are presented. The total artificial heart is a reliable implant for treating critically ill patients with irreversible cardiogenic shock. A bridge to transplantation is feasible with excellent results.

  8. Artificial Intelligence in Astronomy

    Science.gov (United States)

    Devinney, E. J.; Prša, A.; Guinan, E. F.; Degeorge, M.

    2010-12-01

    From the perspective (and bias) as Eclipsing Binary researchers, we give a brief overview of the development of Artificial Intelligence (AI) applications, describe major application areas of AI in astronomy, and illustrate the power of an AI approach in an application developed under the EBAI (Eclipsing Binaries via Artificial Intelligence) project, which employs Artificial Neural Network technology for estimating light curve solution parameters of eclipsing binary systems.

  9. Evolution Engines and Artificial Intelligence

    Science.gov (United States)

    Hemker, Andreas; Becks, Karl-Heinz

    In the last years artificial intelligence has achieved great successes, mainly in the field of expert systems and neural networks. Nevertheless the road to truly intelligent systems is still obscured. Artificial intelligence systems with a broad range of cognitive abilities are not within sight. The limited competence of such systems (brittleness) is identified as a consequence of the top-down design process. The evolution principle of nature on the other hand shows an alternative and elegant way to build intelligent systems. We propose to take an evolution engine as the driving force for the bottom-up development of knowledge bases and for the optimization of the problem-solving process. A novel data analysis system for the high energy physics experiment DELPHI at CERN shows the practical relevance of this idea. The system is able to reconstruct the physical processes after the collision of particles by making use of the underlying standard model of elementary particle physics. The evolution engine acts as a global controller of a population of inference engines working on the reconstruction task. By implementing the system on the Connection Machine (Model CM-2) we use the full advantage of the inherent parallelization potential of the evolutionary approach.

  10. Measuring diet cost at the individual level: a comparison of three methods.

    Science.gov (United States)

    Monsivais, P; Perrigue, M M; Adams, S L; Drewnowski, A

    2013-11-01

    Household-level food spending data are not suitable for population-based studies of the economics of nutrition. This study compared three methods of deriving diet cost at the individual level. Adult men and women (n=164) completed 4-day diet diaries and a food frequency questionnaire (FFQ). Food expenditures over 4 weeks and supermarket prices for 384 foods were obtained. Diet costs (US$/day) were estimated using: (1) diet diaries and expenditures; (2) diet diaries and supermarket prices; and (3) FFQs and supermarket prices. Agreement between the three methods was assessed on the basis of Pearson correlations and limits of agreement. Income-related differences in diet costs were estimated using general linear models. Diet diaries yielded mean (s.d.) diet costs of $10.04 (4.27) based on Method 1 and $8.28 (2.32) based on Method 2. FFQs yielded mean diet costs of $7.66 (2.72) based on Method 3. Correlations between energy intakes and costs were highest for Method 3 (r(2)=0.66), lower for Method 2 (r(2)=0.24) and lowest for Method 1 (r(2)=0.06). Cost estimates were significantly associated with household incomes. The weak association between food expenditures and food intake using Method 1 makes it least suitable for diet and health research. However, merging supermarket food prices with standard dietary assessment tools can provide estimates of individual diet cost that are more closely associated with food consumed. The derivation of individual diet cost can provide insights into some of the economic determinants of food choice, diet quality and health.

  11. [Preparation of nano-nacre artificial bone].

    Science.gov (United States)

    Chen, Jian-ting; Tang, Yong-zhi; Zhang, Jian-gang; Wang, Jian-jun; Xiao, Ying

    2008-12-01

    To assess the improvements in the properties of nano-nacre artificial bone prepared on the basis of nacre/polylactide acid composite artificial bone and its potential for clinical use. The compound of nano-scale nacre powder and poly-D, L-lactide acid (PDLLA) was used to prepare the cylindrical hollow artificial bone, whose properties including raw material powder scale, pore size, porosity and biomechanical characteristics were compared with another artificial bone made of micron-scale nacre powder and PDLLA. Scanning electron microscope showed that the average particle size of the nano-nacre powder was 50.4-/+12.4 nm, and the average pore size of the artificial bone prepared using nano-nacre powder was 215.7-/+77.5 microm, as compared with the particle size of the micron-scale nacre powder of 5.0-/+3.0 microm and the pore size of the resultant artificial bone of 205.1-/+72.0 microm. The porosities of nano-nacre artificial bone and the micron-nacre artificial bone were (65.4-/+2.9)% and (53.4-/+2.2)%, respectively, and the two artificial bones had comparable compressive strength and Young's modulus, but the flexural strength of the nano-nacre artificial bone was lower than that of the micro-nacre artificial bone. The nano-nacre artificial bone allows better biodegradability and possesses appropriate pore size, porosity and biomechanical properties for use as a promising material in bone tissue engineering.

  12. Effects of seven diets on the population dynamics of laboratory cultured Tisbe holothuriae Humes (Copepoda, Harpacticoida)

    Science.gov (United States)

    Miliou, H.; Moraïtou-Apostolopoulou, M.

    1991-09-01

    The harpacticoid copepod Tisbe holothuriae was collected from Saronicos Gulf (Greece) and reared under constant laboratory conditions. In order to study the effects of food on the population dynamics, seven diets were tested: the seaweed Ulva; five artificial compound feeds: the liquid Fryfood® (Waterlife), a powder of Mytilus, yeast, soya and Spirulina, respectively; and a mixed diet consisting of Ulva and Fryfood. The life cycle parameters (mortality, sex ratio, generation time, offspring production) were measured, and the demographic variables [mean generation time (T), net reproductive rate (Ro), and intrinsic rate of natural increase (rm)] were determined. As to their efficiency regarding population dynamics, the diets ranked as follows: (1) Ulva+Fryfood, (2), Ulva, (3) Fryfood, (4) Mytilus, (5) soya, (6) yeast, and (7) Spirulina. In this order they cause a progressive increase of both larval mortality and generation time, a progressive decrease of sex ratio, number of offspring per egg sac, number of egg sacs per female and, consequently, of Ro and rm. The observed differences between diets were most pronounced with respect to offspring production. Of the compound diets, those containing animal extracts were more efficient than those containing vegetable materials. Ulva plays an important role in the nutrition of T. holothuriae, favouring offspring production as well as larval survival, development and pigmentation. Ulva in combination with Fryfood led to a greater copepodid survival and offspring production. This mixed diet proved to be the most favourable for rearing the Greek population of t. holothuriae, resulting in an efficient intrinsic rate of natural increase (rm=0.304) of the population.

  13. Identifying molecular effects of diet through systems biology: influence of herring diet on sterol metabolism and protein turnover in mice.

    Directory of Open Access Journals (Sweden)

    Intawat Nookaew

    Full Text Available BACKGROUND: Changes in lifestyle have resulted in an epidemic development of obesity-related diseases that challenge the healthcare systems worldwide. To develop strategies to tackle this problem the focus is on diet to prevent the development of obesity-associated diseases such as cardiovascular disease (CVD. This will require methods for linking nutrient intake with specific metabolic processes in different tissues. METHODOLOGY/PRINCIPAL FINDING: Low-density lipoprotein receptor-deficient (Ldlr -/- mice were fed a high fat/high sugar diet to mimic a westernized diet, being a major reason for development of obesity and atherosclerosis. The diets were supplemented with either beef or herring, and matched in macronutrient contents. Body composition, plasma lipids and aortic lesion areas were measured. Transcriptomes of metabolically important tissues, e.g. liver, muscle and adipose tissue were analyzed by an integrated approach with metabolic networks to directly map the metabolic effects of diet in these different tissues. Our analysis revealed a reduction in sterol metabolism and protein turnover at the transcriptional level in herring-fed mice. CONCLUSION: This study shows that an integrated analysis of transcriptome data using metabolic networks resulted in the identification of signature pathways. This could not have been achieved using standard clustering methods. In particular, this systems biology analysis could enrich the information content of biomedical or nutritional data where subtle changes in several tissues together affects body metabolism or disease progression. This could be applied to improve diets for subjects exposed to health risks associated with obesity.

  14. AN APPLE GRADING SYSTEM ACCORDING TO EUROPEAN FRUIT QUALITY STANDARDS USING GABOR FILTER AND ARTIFICIAL NEURAL NETWORKS

    Directory of Open Access Journals (Sweden)

    KEYVAN ASEFPOUR VAKILIAN

    2016-04-01

    Full Text Available With the advent of applications of machine learning methods in food engineering in recent decades, several intelligent methods have been introduced in fruit grading technology. In this study, an apple grading system is presented using image’s textural features extraction and artificial intelligence. The objective of this study was to simplify the use of Gabor filter in classification of two varieties of apple fruits (Golden Delicious and Red Delicious in four categories according to the European fruit quality standards. Using this filter, neural network classifier was trained for four category grading of the fruits. Two textural parameters were extracted from each obtained image: mean and variance of energy values of obtained image representing image’s luminous intensity and contrast, respectively. Experimental results indicated that the training of extracted features of about 350 fruits enabled the network to classify the test samples with appropriate accuracy. Compared to the state-of-the-art, the proposed grading categories (‘Extra’, ‘Type 1’, ‘Type 2’ and ‘Rejected’ classes achieved acceptable recognition rates of about 89 % and 92 % overall accuracy for Golden Delicious and Red Delicious varieties, respectively. These experimental results show the appropriate application of proposed method in fast grading of apple fruits. Furthermore, proposed feature extraction and network training methods can be used efficiently in online applications.

  15. Diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: Evidence from randomised controlled trials.

    Science.gov (United States)

    Armah, Charlotte N; Derdemezis, Christos; Traka, Maria H; Dainty, Jack R; Doleman, Joanne F; Saha, Shikha; Leung, Wing; Potter, John F; Lovegrove, Julie A; Mithen, Richard F

    2015-05-01

    Cruciferous-rich diets have been associated with reduction in plasma LDL-cholesterol (LDL-C), which may be due to the action of isothiocyanates derived from glucosinolates that accumulate in these vegetables. This study tests the hypothesis that a diet rich in high glucoraphanin (HG) broccoli will reduce plasma LDL-C. One hundred and thirty volunteers were recruited to two independent double-blind, randomly allocated parallel dietary intervention studies, and were assigned to consume either 400 g standard broccoli or 400 g HG broccoli per week for 12 weeks. Plasma lipids were quantified before and after the intervention. In study 1 (37 volunteers), the HG broccoli diet reduced plasma LDL-C by 7.1% (95% CI: -1.8%, -12.3%, p = 0.011), whereas standard broccoli reduced LDL-C by 1.8% (95% CI +3.9%, -7.5%, ns). In study 2 (93 volunteers), the HG broccoli diet resulted in a reduction of 5.1% (95% CI: -2.1%, -8.1%, p = 0.001), whereas standard broccoli reduced LDL-C by 2.5% (95% CI: +0.8%, -5.7%, ns). When data from the two studies were combined the reduction in LDL-C by the HG broccoli was significantly greater than standard broccoli (p = 0.031). Evidence from two independent human studies indicates that consumption of high glucoraphanin broccoli significantly reduces plasma LDL-C. © 2015 The Authors. Molecular Nutrition & Food Research published by Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Low-fiber diet

    Science.gov (United States)

    ... residue; Low-fiber diet; Fiber restricted diet; Crohn disease - low fiber diet; Ulcerative colitis - low fiber diet; ... them if they do not contain seeds or pulp: Yellow squash (without seeds) Spinach Pumpkin Eggplant Potatoes, ...

  17. Diet and resource partitioning among anurans in irrigated rice fields in Pantanal, Brazil

    Directory of Open Access Journals (Sweden)

    L. Piatti

    Full Text Available Artificial ponds or irrigated systems scattered throughout farmlands can offer important habitats for anurans and can be interesting sites for research on species resources use in a changing landscape. This study describes the diet and resource partitioning among anurans inhabiting irrigated rice fields in the Pantanal region. Twenty categories of prey were found in the stomachs of Leptodactylus chaquensis, L. elenae, L. podicipinus and Rhinella bergi, the most frequent being Coleoptera, Hymenoptera, larvae of Hexapoda, Hemiptera, Diptera and Orthoptera. The great differences found in the diet of these species in rice fields compared to other locations, according to available records in the literature, was the increased importance of Hemipitera and Orthoptera and the decrease in importance of Hymenoptera in the diet of leptodactylids. These differences might be attributed to changes in the availability of resources in response to habitat modification. Although diet composition was very similar among species, niche overlap was larger than expected by chance, suggesting that the competition for food resources is not, or has not been, a significant force in determining the structure of this frog community. Two non-exclusive hypotheses could be considered as a justification for this result: 1 the high niche overlap could result from resource availability, which is sufficient to satisfy all species without any strong competition; 2 or the high values of niche overlap could be a selective force driving species to compete, but there has not been enough time to express a significant divergence in the species diet because the study area is characterised as a dynamic habitat influenced by frequent and cyclical changes.

  18. Review of Artificial Abrasion Test Methods for PV Module Technology

    Energy Technology Data Exchange (ETDEWEB)

    Miller, David C. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Muller, Matt T. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Simpson, Lin J. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-08-01

    This review is intended to identify the method or methods--and the basic details of those methods--that might be used to develop an artificial abrasion test. Methods used in the PV literature were compared with their closest implementation in existing standards. Also, meetings of the International PV Quality Assurance Task Force Task Group 12-3 (TG12-3, which is concerned with coated glass) were used to identify established test methods. Feedback from the group, which included many of the authors from the PV literature, included insights not explored within the literature itself. The combined experience and examples from the literature are intended to provide an assessment of the present industry practices and an informed path forward. Recommendations toward artificial abrasion test methods are then identified based on the experiences in the literature and feedback from the PV community. The review here is strictly focused on abrasion. Assessment methods, including optical performance (e.g., transmittance or reflectance), surface energy, and verification of chemical composition were not examined. Methods of artificially soiling PV modules or other specimens were not examined. The weathering of artificial or naturally soiled specimens (which may ultimately include combined temperature and humidity, thermal cycling and ultraviolet light) were also not examined. A sense of the purpose or application of an abrasion test method within the PV industry should, however, be evident from the literature.

  19. Artificial Intelligence Study (AIS).

    Science.gov (United States)

    1987-02-01

    ARTIFICIAL INTELLIGNECE HARDWARE ....... 2-50 AI Architecture ................................... 2-49 AI Hardware ....................................... 2...ftf1 829 ARTIFICIAL INTELLIGENCE STUDY (RIS)(U) MAY CONCEPTS 1/3 A~NLYSIS AGENCY BETHESA RD R B NOJESKI FED 6? CM-RP-97-1 NCASIFIED /01/6 M |K 1.0...p/ - - ., e -- CAA- RP- 87-1 SAOFŔ)11 I ARTIFICIAL INTELLIGENCE STUDY (AIS) tNo DTICFEBRUARY 1987 LECT 00 I PREPARED BY RESEARCH AND ANALYSIS

  20. Short-term consumption of a high-fat diet impairs whole-body efficiency and cognitive function in sedentary men.

    Science.gov (United States)

    Edwards, Lindsay M; Murray, Andrew J; Holloway, Cameron J; Carter, Emma E; Kemp, Graham J; Codreanu, Ion; Brooker, Helen; Tyler, Damian J; Robbins, Peter A; Clarke, Kieran

    2011-03-01

    We recently showed that a short-term high-fat diet blunted exercise performance in rats, accompanied by increased uncoupling protein levels and greater respiratory uncoupling. In this study, we investigated the effects of a similar diet on physical and cognitive performance in humans. Twenty sedentary men were assessed when consuming a standardized, nutritionally balanced diet (control) and after 7 d of consuming a diet comprising 74% kcal from fat. Efficiency was measured during a standardized exercise task, and cognition was assessed using a computerized assessment battery. Skeletal muscle mitochondrial function was measured using (31)P magnetic resonance spectroscopy. The diet increased mean ± se plasma free fatty acids by 44% (0.32±0.03 vs. 0.46±0.05 mM; Pdiet consumption also increased subjects' simple reaction times (Pdiet blunts whole-body efficiency and cognition in sedentary men. We suggest that this effect may be due to increased respiratory uncoupling.

  1. Some Chemical Elements in Gamma Irradiated Adults of the Mediterranean Fruit Fly, Ceratitis capitata (Wied.) Fed on Different Diets

    International Nuclear Information System (INIS)

    Elakhdar, E.A.H.

    2013-01-01

    The elemental composition of four yeast diets differ in protein composition and mixed with sugar as a carbohydrate source were compared with a standard yeast diet used for the mass rearing of med fly C. capitata. The cost availability and the effects on the quality of reared flies were the main measures for these comparisons. Moreover, the elemental composition of reared flies on the tested diets either irradiated to gamma radiation or normal beside full grown pupae (F1) were detected and compared with those reared on standard diet . Data obtained revealed that ten elements (K, N, Na, P, Ca, Fe, Mg, Zn, Mn and Cu) were detected and classified according to their quantities .However those quantities varied according to the type of used yeast ,insect stage , insect sex and irradiated dose. The major group (K, N, Na and P), moderate group (Ca, Fe and Mg) and minor group (Zn, Mn and Cu) remained unchanged although their quantities were changed inside each group. In addition, a significant increase in K, N, Na, P and Ca when diet No.4 (D4) was used to feed flies. These findings may enhance the opportunity of sterile insect technique (SIT). However Fe and Zn ions were decreased with changing the standard yeast and this is may contradict SIT. Also when normal females fed on all tested yeasts, the concentrations of the ten elements increased as compared to those fed on standard diet. These results may increase the efficiency of sterilized reared insects to compete with the native insects in the field

  2. Log-Linear Model Based Behavior Selection Method for Artificial Fish Swarm Algorithm

    Directory of Open Access Journals (Sweden)

    Zhehuang Huang

    2015-01-01

    Full Text Available Artificial fish swarm algorithm (AFSA is a population based optimization technique inspired by social behavior of fishes. In past several years, AFSA has been successfully applied in many research and application areas. The behavior of fishes has a crucial impact on the performance of AFSA, such as global exploration ability and convergence speed. How to construct and select behaviors of fishes are an important task. To solve these problems, an improved artificial fish swarm algorithm based on log-linear model is proposed and implemented in this paper. There are three main works. Firstly, we proposed a new behavior selection algorithm based on log-linear model which can enhance decision making ability of behavior selection. Secondly, adaptive movement behavior based on adaptive weight is presented, which can dynamically adjust according to the diversity of fishes. Finally, some new behaviors are defined and introduced into artificial fish swarm algorithm at the first time to improve global optimization capability. The experiments on high dimensional function optimization showed that the improved algorithm has more powerful global exploration ability and reasonable convergence speed compared with the standard artificial fish swarm algorithm.

  3. Log-linear model based behavior selection method for artificial fish swarm algorithm.

    Science.gov (United States)

    Huang, Zhehuang; Chen, Yidong

    2015-01-01

    Artificial fish swarm algorithm (AFSA) is a population based optimization technique inspired by social behavior of fishes. In past several years, AFSA has been successfully applied in many research and application areas. The behavior of fishes has a crucial impact on the performance of AFSA, such as global exploration ability and convergence speed. How to construct and select behaviors of fishes are an important task. To solve these problems, an improved artificial fish swarm algorithm based on log-linear model is proposed and implemented in this paper. There are three main works. Firstly, we proposed a new behavior selection algorithm based on log-linear model which can enhance decision making ability of behavior selection. Secondly, adaptive movement behavior based on adaptive weight is presented, which can dynamically adjust according to the diversity of fishes. Finally, some new behaviors are defined and introduced into artificial fish swarm algorithm at the first time to improve global optimization capability. The experiments on high dimensional function optimization showed that the improved algorithm has more powerful global exploration ability and reasonable convergence speed compared with the standard artificial fish swarm algorithm.

  4. Research Review: The Role of Diet in the Treatment of Attention-Deficit/Hyperactivity Disorder--An Appraisal of the Evidence on Efficacy and Recommendations on the Design of Future Studies

    Science.gov (United States)

    Stevenson, Jim; Buitelaar, Jan; Cortese, Samuele; Ferrin, Maite; Konofal, Eric; Lecendreux, Michel; Simonoff, Emily; Wong, Ian C. K.; Sonuga-Barke, Edmund

    2014-01-01

    Background: The efficacy of three dietary treatments for ADHD has been repeatedly tested in randomized controlled trials (RCTs). These interventions are restricted elimination diets (RED), artificial food colour elimination (AFCE) and supplementation with free fatty acids (SFFA). There have been three systematic reviews and associated…

  5. Quality Management Framework for Total Diet Study centres in Europe.

    Science.gov (United States)

    Pité, Marina; Pinchen, Hannah; Castanheira, Isabel; Oliveira, Luisa; Roe, Mark; Ruprich, Jiri; Rehurkova, Irena; Sirot, Veronique; Papadopoulos, Alexandra; Gunnlaugsdóttir, Helga; Reykdal, Ólafur; Lindtner, Oliver; Ritvanen, Tiina; Finglas, Paul

    2018-02-01

    A Quality Management Framework to improve quality and harmonization of Total Diet Study practices in Europe was developed within the TDS-Exposure Project. Seventeen processes were identified and hazards, Critical Control Points and associated preventive and corrective measures described. The Total Diet Study process was summarized in a flowchart divided into planning and practical (sample collection, preparation and analysis; risk assessment analysis and publication) phases. Standard Operating Procedures were developed and implemented in pilot studies in five organizations. The flowchart was used to develop a quality framework for Total Diet Studies that could be included in formal quality management systems. Pilot studies operated by four project partners were visited by project assessors who reviewed implementation of the proposed framework and identified areas that could be improved. The quality framework developed can be the starting point for any Total Diet Study centre and can be used within existing formal quality management approaches. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Predictors of dieting and non-dieting approaches among adults living in Australia

    Directory of Open Access Journals (Sweden)

    Stuart Leske

    2017-02-01

    Full Text Available Abstract Background There is a dearth of research comparing why dieting and non-dieting approaches are adopted. A greater understanding of reasons underlying dieting and non-dieting attempts will help to identify target beliefs for interventions to support and motivate adults to attempt whatever approach they are willing and/or able to pursue. We investigated the predictors of dieting and non-dieting approaches in Australian adults using predictors that were identified in a previous qualitative study. Methods We conducted a prospective study, with two waves of data collection occurring 4 weeks apart. At baseline, participants completed a questionnaire assessing constructs drawn from the theory of planned behaviour (attitude, subjective norm, and self-efficacy, past behaviour, non-planning, attributions for dieting failure, weight control beliefs, and dieting and non-dieting intentions. We used path modelling to analyse responses. Results At baseline, 719 adults (52.2% male aged between 18 and 76 completed the questionnaire. Four weeks later, 64% of participants (n = 461 reported on their dieting and non-dieting behaviour in the past month. Past behaviour, attitude, subjective norm, and self-identity significantly predicted dieting intentions. Dieting intentions and past behaviour significantly predicted dieting behaviour, while non-planning and self-efficacy did not. The model explained 74.8% of the variance in intention and 52.9% of the variance in behaviour. While most findings were similar for the non-dieting model, subjective norms and self-identity did not predict intention, while self-efficacy and self-identity both predicted non-dieting behaviour directly. The non-dieting model explained 58.2% of the variance in intention and 37.5% of the variance in behaviour. Conclusions The findings from this study provide support for the application of TPB and identity theory constructs in the context of both dieting and non-dieting behaviour

  7. Application of hybrid artificial fish swarm algorithm based on similar fragments in VRP

    Science.gov (United States)

    Che, Jinnuo; Zhou, Kang; Zhang, Xueyu; Tong, Xin; Hou, Lingyun; Jia, Shiyu; Zhen, Yiting

    2018-03-01

    Focused on the issue that the decrease of convergence speed and the precision of calculation at the end of the process in Artificial Fish Swarm Algorithm(AFSA) and instability of results, a hybrid AFSA based on similar fragments is proposed. Traditional AFSA enjoys a lot of obvious advantages in solving complex optimization problems like Vehicle Routing Problem(VRP). AFSA have a few limitations such as low convergence speed, low precision and instability of results. In this paper, two improvements are introduced. On the one hand, change the definition of the distance for artificial fish, as well as increase vision field of artificial fish, and the problem of speed and precision can be improved when solving VRP. On the other hand, mix artificial bee colony algorithm(ABC) into AFSA - initialize the population of artificial fish by the ABC, and it solves the problem of instability of results in some extend. The experiment results demonstrate that the optimal solution of the hybrid AFSA is easier to approach the optimal solution of the standard database than the other two algorithms. In conclusion, the hybrid algorithm can effectively solve the problem that instability of results and decrease of convergence speed and the precision of calculation at the end of the process.

  8. Research on artificial intelligence systems for nuclear installations

    International Nuclear Information System (INIS)

    Sakuma, Minoru

    1992-01-01

    The development and utilization of atomic energy in Japan has be advanced in conformity with the long term plan of atomic energy development and utilization decided in 1987. As one of the basic targets, the upbringing of creative and innovative science and technology is put up. Artificial intelligence technology has been positioned as one of the important basic technologies for promoting future atomic energy development. The research and development of artificial intelligence technology have been advanced aiming at making nuclear power stations autonomous, by the guidance of Science and Technology Agency and the cooperation of several research institutes. The upbringing of creative science and technology, the preponderant development of basic technology, the concept of developing the basic technology for atomic energy, the concept of autonomous plants, the standard for autonomy, the approach to autonomous plants, the present state of the researches in respective research institutes on autonomous operation and autonomous maintenance are described. (K.I.)

  9. Development of an alternative artificial soil for earthworm toxicity testing in tropical countries.

    NARCIS (Netherlands)

    de Silva, M.; van Gestel, C.A.M.

    2009-01-01

    The standard soil invertebrate toxicity tests developed by OECD and ISO use an artificial soil as the test substrate, which contains sphagnum peat as a component. This type of peat is not widely available. Investigation of possible alternative substrates using locally available materials therefore

  10. Amounts of artificial food dyes and added sugars in foods and sweets commonly consumed by children.

    Science.gov (United States)

    Stevens, Laura J; Burgess, John R; Stochelski, Mateusz A; Kuczek, Thomas

    2015-04-01

    Artificial food colors (AFCs) are used to color many beverages, foods, and sweets in the United States and throughout the world. In the United States, the Food and Drug Administration (FDA) limits the AFCs allowed in the diet to 9 different colors. The FDA certifies each batch of manufactured AFCs to guarantee purity and safety. The amount certified has risen from 12 mg/capita/d in 1950 to 62 mg/capita/d in 2010. Previously, we reported the amounts of AFCs in commonly consumed beverages. In this article, the amounts of AFCs in commonly consumed foods and sweets are reported. In addition, the amount of sugars in each product is included. Amounts of AFCs reported here along with the beverage data show that many children could be consuming far more dyes than previously thought. Clinical guidance is given to help caregivers avoid AFCs and reduce the amount of sugars in children's diets. © The Author(s) 2014.

  11. Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis

    Directory of Open Access Journals (Sweden)

    Svenja Sydor

    2017-05-01

    Full Text Available Objective: Alterations in sphingolipid and ceramide metabolism have been associated with various diseases, including nonalcoholic fatty liver disease (NAFLD. Acid sphingomyelinase (ASM converts the membrane lipid sphingomyelin to ceramide, thereby affecting membrane composition and domain formation. We investigated the ways in which the Asm knockout (Smpd1−/− genotype affects diet-induced NAFLD. Methods: Smpd1−/− mice and wild type controls were fed either a standard or Western diet (WD for 6 weeks. Liver and adipose tissue morphology and mRNA expression were assessed. Quantitative proteome analysis of liver tissue was performed. Expression of selected genes was quantified in adipose and liver tissue of obese NAFLD patients. Results: Although Smpd1−/− mice exhibited basal steatosis with normal chow, no aggravation of NAFLD-type injury was observed with a Western diet. This protective effect was associated with the absence of adipocyte hypertrophy and the increased expression of genes associated with brown adipocyte differentiation. In white adipose tissue from obese patients with NAFLD, no expression of these genes was detectable. To further elucidate which pathways in liver tissue may be affected by Smpd1−/−, we performed an unbiased proteome analysis. Protein expression in WD-fed Smpd1−/− mice indicated a reduction in Rictor (mTORC2 activity; this reduction was confirmed by diminished Akt phosphorylation and altered mRNA expression of Rictor target genes. Conclusion: These findings indicate that the protective effect of Asm deficiency on diet-induced steatosis is conferred by alterations in adipocyte morphology and lipid metabolism and by reductions in Rictor activation. Keywords: Ceramide, NAFLD, Rictor, Western diet

  12. Prevalence of micronutrient deficiency in popular diet plans

    Directory of Open Access Journals (Sweden)

    Calton Jayson B

    2010-06-01

    Full Text Available Abstract Background Research has shown micronutrient deficiency to be scientifically linked to a higher risk of overweight/obesity and other dangerous and debilitating diseases. With more than two-thirds of the U.S. population overweight or obese, and research showing that one-third are on a diet at any given time, a need existed to determine whether current popular diet plans could protect followers from micronutrient deficiency by providing the minimum levels of 27 micronutrients, as determined by the U.S. Food and Drug Administrations (FDA Reference Daily Intake (RDI guidelines. Methods Suggested daily menus from four popular diet plans (Atkins for Life diet, The South Beach Diet, the DASH diet, the DASH diet were evaluated. Calorie and micronutrient content of each ingredient, in each meal, were determined by using food composition data from the U.S. Department of Agriculture Nutrient Database for Standard Reference. The results were evaluated for sufficiency and total calories and deficient micronutrients were identified. The diet plans that did not meet 100% sufficiency by RDI guidelines for each of the 27 micronutrients were re-analyzed; (1 to identify a micronutrient sufficient calorie intake for all 27 micronutrients, and (2 to identify a second micronutrient sufficient calorie intake when consistently low or nonexistent micronutrients were removed from the sufficiency requirement. Results Analysis determined that each of the four popular diet plans failed to provide minimum RDI sufficiency for all 27 micronutrients analyzed. The four diet plans, on average, were found to be RDI sufficient in (11.75 ± 2.02; mean ± SEM of the analyzed 27 micronutrients and contain (1748.25 ± 209.57 kcal. Further analysis of the four diets found that an average calorie intake of (27,575 ± 4660.72 would be required to achieve sufficiency in all 27 micronutrients. Six micronutrients (vitamin B7, vitamin D, vitamin E, chromium, iodine and molybdenum were

  13. Quo Vadis, Artificial Intelligence?

    OpenAIRE

    Berrar, Daniel; Sato, Naoyuki; Schuster, Alfons

    2010-01-01

    Since its conception in the mid 1950s, artificial intelligence with its great ambition to understand and emulate intelligence in natural and artificial environments alike is now a truly multidisciplinary field that reaches out and is inspired by a great diversity of other fields. Rapid advances in research and technology in various fields have created environments into which artificial intelligence could embed itself naturally and comfortably. Neuroscience with its desire to understand nervou...

  14. Inteligencia artificial en vehiculo

    OpenAIRE

    Amador Díaz, Pedro

    2012-01-01

    Desarrollo de un robot seguidor de líneas, en el que se implementan diversas soluciones de las áreas de sistemas embebidos e inteligencia artificial. Desenvolupament d'un robot seguidor de línies, en el qual s'implementen diverses solucions de les àrees de sistemes encastats i intel·ligència artificial. Follower robot development of lines, in which various solutions are implemented in the areas of artificial intelligence embedded systems.

  15. High-fiber rye diet increases ileal excretion of energy and macronutrients compared with low-fiber wheat diet independent of meal frequency in ileostomy subjects.

    Science.gov (United States)

    Isaksson, Hanna; Landberg, Rikard; Sundberg, Birgitta; Lundin, Eva; Hallmans, Göran; Zhang, Jie-Xian; Tidehag, Per; Erik Bach Knudsen, Knud; Moazzami, Ali A; Aman, Per

    2013-01-01

    Whole-grain foods and cereal dietary fiber intake is associated with lower body weight. This may partly result from lower energy utilization of high-fiber diets. In the present study, the impact on ileal excretion of energy and macronutrients in response to a rye bread high-fiber diet compared to a refined wheat low-fiber diet was investigated. Furthermore, the effect of meal frequency on apparent absorption of nutrients was studied for the first time. Ten participants that had undergone ileostomy consumed standardized iso-caloric diets, including low-fiber wheat bread (20 g dietary fiber per day) for 2 weeks followed by high-fiber rye bread (52 g dietary fiber per day) for 2 weeks. The diets were consumed in an ordinary (three meals per day) and a nibbling (seven meals per day) meal frequency in a cross-over design. Ileal effluents were collected during 24 h at the third day of each of the four dietary periods and analyzed for gross energy and nutrient contents. The results showed that intake of rye bread high-fiber diet compared to the refined wheat low-fiber diet caused an increase in ileal excretion of energy and macronutrients. The effect was independent of meal frequency. This suggests that a high intake of rye may result in lower availability of macronutrients for small intestinal digestion and absorption. A regular intake of rye may therefore have implications for weight management.

  16. Criminal Aspects of Artificial Abortion

    OpenAIRE

    Hartmanová, Leona

    2016-01-01

    Criminal Aspects of Artificial Abortion This diploma thesis deals with the issue of artificial abortion, especially its criminal aspects. Legal aspects are not the most important aspects of artificial abortion. Social, ethical or ideological aspects are of the same importance but this diploma thesis cannot analyse all of them. The main issue with artificial abortion is whether it is possible to force a pregnant woman to carry a child and give birth to a child when she cannot or does not want ...

  17. Open- and Closed-Formula Laboratory Animal Diets and Their Importance to Research

    OpenAIRE

    Barnard, Dennis E; Lewis, Sherry M; Teter, Beverly B; Thigpen, Julius E

    2009-01-01

    Almost 40 y ago the scientific community was taking actions to control environmental factors that contribute to variation in the responses of laboratory animals to scientific manipulation. Laboratory animal diet was recognized as an important variable. During the 1970s, the American Institute of Nutrition, National Academy of Science, Institute of Laboratory Animal Resources, and Laboratory Animals Centre Diets Advisory Committee supported the use of ‘standard reference diets’ in biomedical r...

  18. A study of the prebiotic-like effects of tomato juice consumption in rats with diet-induced non-alcoholic fatty liver disease (NAFLD).

    Science.gov (United States)

    García-Alonso, F J; González-Barrio, R; Martín-Pozuelo, G; Hidalgo, N; Navarro-González, I; Masuero, D; Soini, E; Vrhovsek, U; Periago, M J

    2017-10-18

    Gut microbiota may play a role in the pathogenesis of NAFLD. We investigated whether tomato juice consumption for 5 weeks could ameliorate high-fat diet-induced alterations in certain intestinal bacterial groups and products arising from their metabolism (short-chain fatty acids and microbial phenolic catabolites). For this, we used a rat model with NAFLD induced by a high-fat diet, involving four experimental groups: NA (standard diet and water), NL (standard diet and tomato juice), HA (high-fat diet and water) and HL (high-fat diet and tomato juice). The onset of NAFLD impacted the gut microbiota profile, reducing the abundance of Bifidobacterium and Lactobacillus and increasing that of Enterobacteriaceae. Also, reduced concentrations of propionate, butyrate and phenolic catabolites and an increased acetate to propionate (Ac : Pr) ratio were observed. Tomato juice intake partially ameliorated high-fat diet-induced disturbances, particularly by increasing Lactobacillus abundance and diminishing the Ac : Pr ratio, suggesting a potential improvement of the metabolic pattern of NAFLD.

  19. The Effect of Low Calcium Diet on Bone in Ovariectomized Mice

    OpenAIRE

    Minematsu, Akira; Yoshimura, Osamu; Yotsuji, Hirofumi; Ichigo, Hirozo; Takayanagi, Kiyomi; Kobayashi, Ryuji; Hosoda, Masataka; Sasaki, Hisato; Maejima, Hiroshi; Matsuda, Yuichi; Tanaka, Sachiko; Kanemura, Naohiko; Matsuo, Akihisa

    2000-01-01

    This study investigates the effects of Ca on bone in the ovariectomized mice. Twenty-six female ICR mice aged 5 weeks were used. They were ovariectomized (OVX) or sham-operated (SHAM) and fed standard mouse diet (SF) or special low calcium diet (L.Ca), respectively. All animals were sacrificed at day 100 after operation. Mechanical strength of the left femur and tibia was measured by the three-point bending strength test. The bones were dried, weighed and burned to ash. Correlation between me...

  20. Inhibition of Neuroblastoma Tumor Growth by Ketogenic Diet and/or Calorie Restriction in a CD1-Nu Mouse Model.

    Directory of Open Access Journals (Sweden)

    Raphael Johannes Morscher

    Full Text Available Neuroblastoma is a malignant pediatric cancer derived from neural crest cells. It is characterized by a generalized reduction of mitochondrial oxidative phosphorylation. The goal of the present study was to investigate the effects of calorie restriction and ketogenic diet on neuroblastoma tumor growth and monitor potential adaptive mechanisms of the cancer's oxidative phosphorylation system.Xenografts were established in CD-1 nude mice by subcutaneous injection of two neuroblastoma cell lines having distinct genetic characteristics and therapeutic sensitivity [SH-SY5Y and SK-N-BE(2]. Mice were randomized to four treatment groups receiving standard diet, calorie-restricted standard diet, long chain fatty acid based ketogenic diet or calorie-restricted ketogenic diet. Tumor growth, survival, metabolic parameters and weight of the mice were monitored. Cancer tissue was evaluated for diet-induced changes of proliferation indices and multiple oxidative phosphorylation system parameters (respiratory chain enzyme activities, western blot analysis, immunohistochemistry and mitochondrial DNA content.Ketogenic diet and/or calorie restriction significantly reduced tumor growth and prolonged survival in the xenograft model. Neuroblastoma growth reduction correlated with decreased blood glucose concentrations and was characterized by a significant decrease in Ki-67 and phospho-histone H3 levels in the diet groups with low tumor growth. As in human tumor tissue, neuroblastoma xenografts showed distinctly low mitochondrial complex II activity in combination with a generalized low level of mitochondrial oxidative phosphorylation, validating the tumor model. Neuroblastoma showed no ability to adapt its mitochondrial oxidative phosphorylation activity to the change in nutrient supply induced by dietary intervention.Our data suggest that targeting the metabolic characteristics of neuroblastoma could open a new front in supporting standard therapy regimens

  1. Inhibition of Neuroblastoma Tumor Growth by Ketogenic Diet and/or Calorie Restriction in a CD1-Nu Mouse Model.

    Science.gov (United States)

    Morscher, Raphael Johannes; Aminzadeh-Gohari, Sepideh; Feichtinger, René Gunther; Mayr, Johannes Adalbert; Lang, Roland; Neureiter, Daniel; Sperl, Wolfgang; Kofler, Barbara

    2015-01-01

    Neuroblastoma is a malignant pediatric cancer derived from neural crest cells. It is characterized by a generalized reduction of mitochondrial oxidative phosphorylation. The goal of the present study was to investigate the effects of calorie restriction and ketogenic diet on neuroblastoma tumor growth and monitor potential adaptive mechanisms of the cancer's oxidative phosphorylation system. Xenografts were established in CD-1 nude mice by subcutaneous injection of two neuroblastoma cell lines having distinct genetic characteristics and therapeutic sensitivity [SH-SY5Y and SK-N-BE(2)]. Mice were randomized to four treatment groups receiving standard diet, calorie-restricted standard diet, long chain fatty acid based ketogenic diet or calorie-restricted ketogenic diet. Tumor growth, survival, metabolic parameters and weight of the mice were monitored. Cancer tissue was evaluated for diet-induced changes of proliferation indices and multiple oxidative phosphorylation system parameters (respiratory chain enzyme activities, western blot analysis, immunohistochemistry and mitochondrial DNA content). Ketogenic diet and/or calorie restriction significantly reduced tumor growth and prolonged survival in the xenograft model. Neuroblastoma growth reduction correlated with decreased blood glucose concentrations and was characterized by a significant decrease in Ki-67 and phospho-histone H3 levels in the diet groups with low tumor growth. As in human tumor tissue, neuroblastoma xenografts showed distinctly low mitochondrial complex II activity in combination with a generalized low level of mitochondrial oxidative phosphorylation, validating the tumor model. Neuroblastoma showed no ability to adapt its mitochondrial oxidative phosphorylation activity to the change in nutrient supply induced by dietary intervention. Our data suggest that targeting the metabolic characteristics of neuroblastoma could open a new front in supporting standard therapy regimens. Therefore, we propose

  2. Effect of Mediterranean diet with and without weight loss on apolipoprotein B100 metabolism in men with metabolic syndrome

    Science.gov (United States)

    The objective of this study was to assess the effect of a Mediterranean diet (MedDiet) with and without weight loss (WL) on apolipoprotein B100 (apoB100) metabolism in men with metabolic syndrome. The diet of 19 men with metabolic syndrome (age, 24–62 years) was first standardized to a North America...

  3. Estimates of diet selection in cattle grazing cornstalk residues by measurement of chemical composition and near infrared reflectance spectroscopy of diet samples collected by ruminal evacuation.

    Science.gov (United States)

    Petzel, Emily A; Smart, Alexander J; St-Pierre, Benoit; Selman, Susan L; Bailey, Eric A; Beck, Erin E; Walker, Julie A; Wright, Cody L; Held, Jeffrey E; Brake, Derek W

    2018-05-04

    Six ruminally cannulated cows (570 ± 73 kg) fed corn residues were placed in a 6 × 6 Latin square to evaluate predictions of diet composition from ruminally collected diet samples. After complete ruminal evacuation, cows were fed 1-kg meals (dry matter [DM]-basis) containing different combinations of cornstalk and leaf and husk (LH) residues in ratios of 0:100, 20:80, 40:60, 60:40, 80:20, and 100:0. Diet samples from each meal were collected by removal of ruminal contents after 1-h and were either unrinsed, hand-rinsed or machine-rinsed to evaluate effects of endogenous compounds on predictions of diet composition. Diet samples were analyzed for neutral (NDF) and acid (ADF) detergent fiber, acid detergent insoluble ash (ADIA), acid detergent lignin (ADL), crude protein (CP), and near infrared reflectance spectroscopy (NIRS) to calculate diet composition. Rinsing type increased NDF and ADF content and decreased ADIA and CP content of diet samples (P content of diet samples. Differences in concentration between cornstalk and LH residues within each chemical component were standardized by calculating a coefficient of variation (CV). Accuracy and precision of estimates of diet composition were analyzed by regressing predicted diet composition and known diet composition. Predictions of diet composition were improved by increasing differences in concentration of chemical components between cornstalk and LH residues up to a CV of 22.6 ± 5.4%. Predictions of diet composition from unrinsed ADIA and machine-rinsed NIRS had the greatest accuracy (slope = 0.98 and 0.95, respectively) and large coefficients of determination (r2 = 0.86 and 0.74, respectively). Subsequently, a field study (Exp. 2) was performed to evaluate predictions of diet composition in cattle (646 ± 89 kg) grazing corn residue. Five cows were placed in 1 of 10 paddocks and allowed to graze continuously or to strip-graze corn residues. Predictions of diet composition from ADIA, ADL, and NIRS did not

  4. The New Nordic Diet as a prototype for regional sustainable diets

    DEFF Research Database (Denmark)

    Bügel, Susanne Gjedsted; Hertwig, Jostein; Kahl, Johannes

    2016-01-01

    A main challenge in sustainable food systems is to link sustainable production to sustainable diets and consumption patterns. The new Nordic diet (NND) builds on and shares the Mediterranean diet (MD) thinking, but utilizes the ingredients and flavours of a northern climate. In both diets...... both wild and domesticated sources. Both diets have been associated with health benefits. The NND is a prototype regional diet taking health, food culture, palatability and the environment into account. Thus, the principles and guidelines could be applied in any region of the world. There are currently...

  5. Gluten-free diet and the possibility of enriching the diet coeliacs

    OpenAIRE

    BLAŽKOVÁ, Klára

    2014-01-01

    This thesis deals with the gluten-free diet and its possible enrichment. It is divided into two parts. The first part includes chapters such as history of gluten-free diet, basics of a gluten free diet, the first step in the introduction of a gluten-free diet, gluten-free food labeling legislation and the use of alcohol on a gluten-free diet. The practical part is focused on enriching the diet celiac patients. I focused on the preparation of bakery products for celiac, I have designed and pra...

  6. Diet, Alcohol Consumption and Serum Lipid Levels of Elderly Men ...

    African Journals Online (AJOL)

    Methodology: Elderly subjects attending quarterly medical lectures organized by a non-governmental organization at the Federal Medical Centre, Asaba were recruited. Information on diet, alcohol consumption and hypertension were obtained and serum lipids were determined using standard cholesterol / low density ...

  7. Standardization of the 24-hour diet recall calibration method used in the european prospective investigation into cancer and nutrition (EPIC): general concepts and preliminary results.

    Science.gov (United States)

    Slimani, N; Ferrari, P; Ocké, M; Welch, A; Boeing, H; Liere, M; Pala, V; Amiano, P; Lagiou, A; Mattisson, I; Stripp, C; Engeset, D; Charrondière, R; Buzzard, M; Staveren, W; Riboli, E

    2000-12-01

    Despite increasing interest in the concept of calibration in dietary surveys, there is still little experience in the use and standardization of a common reference dietary method, especially in international studies. In this paper, we present the general theoretical framework and the approaches developed to standardize the computer-assisted 24 h diet recall method (EPIC-SOFT) used to collect about 37 000 24-h dietary recall measurements (24-HDR) from the 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). In addition, an analysis of variance was performed to examine the level of standardization of EPIC-SOFT across the 90 interviewers involved in the study. The analysis of variance used a random effects model in which mean energy intake per interviewer was used as the dependent variable, while age, body mass index (BMI), energy requirement, week day, season, special diet, special day, physical activity and the EPIC-SOFT version were used as independent variables. The analysis was performed separately for men and women. The results show no statistical difference between interviewers in all countries for men and five out of eight countries for women, after adjustment for physical activity and the EPIC-SOFT program version used, and the exclusion of one interviewer in Germany (for men), and one in Denmark (for women). These results showed an interviewer effect in certain countries and a significant difference between gender, suggesting an underlying respondent's effect due to the higher under-reporting among women that was consistently observed in EPIC. However, the actual difference between interviewer and country mean energy intakes is about 10%. Furthermore, no statistical differences in mean energy intakes were observed across centres from the same country, except in Italy and Germany for men, and France and Spain for women, where the populations were recruited from areas scattered throughout the countries. Despite

  8. Heart disease and diet

    Science.gov (United States)

    Diet - heart disease; CAD - diet; Coronary artery disease - diet; Coronary heart disease - diet ... diet and lifestyle can reduce your risk of: Heart disease, heart attacks, and stroke Conditions that lead ...

  9. Use of Nutrition Standards to Improve Nutritional Quality of Hospital Patient Meals: Findings from New York City's Healthy Hospital Food Initiative.

    Science.gov (United States)

    Moran, Alyssa; Lederer, Ashley; Johnson Curtis, Christine

    2015-11-01

    Most hospital patient meals are considered regular-diet meals; these meals are not required to meet comprehensive nutrition standards for a healthy diet. Although programs exist to improve nutrition in hospital food, the focus is on retail settings such as vending machines and cafeterias vs patient meals. New York City's Healthy Hospital Food Initiative (HHFI) provides nutrition standards for regular-diet meals that hospitals can adopt, in addition to retail standards. This study was undertaken to describe regular-diet patient menus before and after implementation of the HHFI nutrition standards. The study involved pre- and post- menu change analyses of hospitals participating in the HHFI between 2010 and 2014. Eight New York City hospitals, selected based on voluntary participation in the HHFI, were included in the analyses. Nutritional content of regular-diet menus were compared with the HHFI nutrition standards. Nutrient analysis and exact Wilcoxon signed-rank tests were used for the analysis of the data. At baseline, no regular-diet menu met all HHFI standards, and most exceeded the daily limits for percentage of calories from fat (n=5), percentage of calories from saturated fat (n=5), and milligrams of sodium (n=6), and they did not meet the minimum grams of fiber (n=7). Hospitals met all key nutrient standards after implementation, increasing fiber (25%, Pfood service operations, indicating feasibility of this framework in a range of hospital settings. Copyright © 2015 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  10. A low-fat Diet improves insulin sensitivity in patients with type 1 diabetes

    DEFF Research Database (Denmark)

    Rosenfalck, AM; Almdal, Thomas Peter; Viggers, Lone

    2006-01-01

    diet (P = 0.039). The daily protein and carbohydrate intake increased (+4.4% of total energy intake, P = 0.0049 and +2.5%, P = 0.34, respectively), while alcohol intake decreased (-3.2% of total energy intake, P = 0.02). There was a significant improvement in insulin sensitivity on the isocaloric, low-fat......AIMS: To compare the effects on insulin sensitivity, body composition and glycaemic control of the recommended standard weight-maintaining diabetes diet and an isocaloric low-fat diabetes diet during two, 3-month periods in patients with Type 1 diabetes. METHODS: Thirteen Type 1 patients were...... by the insulin clamp technique at baseline and after each of the diet intervention periods. RESULTS: On an isocaloric low-fat diet, Type 1 diabetic patients significantly reduced the proportion of fat in the total daily energy intake by 12.1% (or -3.6% of total energy) as compared with a conventional diabetes...

  11. Effect of milking frequency and diet on milk production, energy balance, and reproduction in dairy cows.

    Science.gov (United States)

    Patton, J; Kenny, D A; Mee, J F; O'Mara, F P; Wathes, D C; Cook, M; Murphy, J J

    2006-05-01

    The objective of this study was to determine the effects of reduced milking frequency and increased dietary energy density in early lactation on milk production, energy balance, and subsequent fertility. Sixty-six spring-calving, multiparous Holstein-Friesian cows were assigned to 1 of 3 treatment groups: once-daily milking on a standard diet (1xST); 3-times daily milking on a standard diet (3xST); and 3-times daily milking on a high-energy diet. Treatments were imposed for the first 28 d of lactation, after which all groups were milked twice daily and fed the standard diet. During the treatment period, the 1xST cows had 19.6% lower milk yield and higher milk fat and milk protein concentrations (15.7 and 10.2%, respectively) compared with 3xST. Dry matter (DM) intake was similar between 1xST and 3xST during the treatment period (12.64 vs. 13.25 kg/ d; SED = 0.82). Daily energy balance was less negative for 1xST compared with 3xST during wk 1 to 3 of lactation [-3.92 vs. -5.30 unité fourragère lait (UFL)/d; SED = 0.65; 1 UFL is equal to the net energy for lactation of 1 kg of standard air-dry barley]. During the treatment period, the cows on the high-energy diet had 17% higher milk yield, higher DM intake (15.5 vs. 13.9 kg/d; SED = 0.71), and similar energy balance (-4.45 vs. -4.35 UFL/d; SED = 0.65) compared to 3xST. Diet had no significant effect on any of the fertility variables measured. The interval to first ovulation was shorter for 1xST than 3xST (18.3d vs. 28.6d; SED = 1.76). In conclusion, once-daily milking in early lactation may promote earlier resumption of ovarian cyclicity, mediated through improved nutritional status.

  12. Artificial Evolution for the Detection of Group Identities in Complex Artificial Societies

    DEFF Research Database (Denmark)

    Grappiolo, Corrado; Togelius, Julian; Yannakakis, Georgios N.

    2013-01-01

    This paper aims at detecting the presence of group structures in complex artificial societies by solely observing and analysing the interactions occurring among the artificial agents. Our approach combines: (1) an unsupervised method for clustering interactions into two possible classes, namely in...

  13. Artificial intelligence

    International Nuclear Information System (INIS)

    Perret-Galix, D.

    1992-01-01

    A vivid example of the growing need for frontier physics experiments to make use of frontier technology is in the field of artificial intelligence and related themes. This was reflected in the second international workshop on 'Software Engineering, Artificial Intelligence and Expert Systems in High Energy and Nuclear Physics' which took place from 13-18 January at France Telecom's Agelonde site at La Londe des Maures, Provence. It was the second in a series, the first having been held at Lyon in 1990

  14. Nutrient adequacy of a very low-fat vegan diet.

    Science.gov (United States)

    Dunn-Emke, Stacey R; Weidner, Gerdi; Pettengill, Elaine B; Marlin, Ruth O; Chi, Christine; Ornish, Dean M

    2005-09-01

    This study assessed the nutrient adequacy of a very low-fat vegan diet. Thirty-nine men (mean age=65 years) with early stage prostate cancer who chose the "watchful waiting" approach to disease management, were instructed by a registered dietitian and a chef on following a very low-fat (10%) vegan diet with the addition of a fortified soy protein powdered beverage. Three-day food diaries, excluding vitamin and mineral supplements, were analyzed and nutrient values were compared against Dietary Reference Intakes (DRI). Mean dietary intake met the recommended DRIs. On the basis of the Adequate Intake standard, a less than adequate intake was observed for vitamin D. This demonstrates that a very low-fat vegan diet with comprehensive nutrition education emphasizing nutrient-fortified plant foods is nutritionally adequate, with the exception of vitamin D. Vitamin D supplementation, especially for those with limited sun exposure, can help assure nutritional adequacy.

  15. Vitamin D and ferritin correlation with chronic neck pain using standard statistics and a novel artificial neural network prediction model.

    Science.gov (United States)

    Eloqayli, Haytham; Al-Yousef, Ali; Jaradat, Raid

    2018-02-15

    Despite the high prevalence of chronic neck pain, there is limited consensus about the primary etiology, risk factors, diagnostic criteria and therapeutic outcome. Here, we aimed to determine if Ferritin and Vitamin D are modifiable risk factors with chronic neck pain using slandered statistics and artificial intelligence neural network (ANN). Fifty-four patients with chronic neck pain treated between February 2016 and August 2016 in King Abdullah University Hospital and 54 patients age matched controls undergoing outpatient or minor procedures were enrolled. Patients and control demographic parameters, height, weight and single measurement of serum vitamin D, Vitamin B12, ferritin, calcium, phosphorus, zinc were obtained. An ANN prediction model was developed. The statistical analysis reveals that patients with chronic neck pain have significantly lower serum Vitamin D and Ferritin (p-value artificial neural network can be of future benefit in classification and prediction models for chronic neck pain. We hope this initial work will encourage a future larger cohort study addressing vitamin D and iron correction as modifiable factors and the application of artificial intelligence models in clinical practice.

  16. Diabetes preventive gluten-free diet decreases the number of caecal bacteria in non-obese diabetic mice

    DEFF Research Database (Denmark)

    Hansen, Axel Kornerup; Ling, Fenjung; Anne, Kaas

    2006-01-01

    disease prevention. Methods Two groups of NOD mice from the age of 3 weeks were fed either a gluten-free diet or a standard diet. Each diabetic mouse, when diagnosed, along with a non-diabetic mouse from the same diet group and two nondiabetic mice from the alternate diet group were euthanized and sampled...... qualitatively and quantitatively substantially altered the composition of the caecal bacterial flora in NOD mice. Although Gram-positive bacteria might influence the beta cells through certain digestive products, it is more likely to assume that any effect on diabetes incidence is immunological. Copyright (c...

  17. Effect of a diet enriched with green-lipped mussel on pain behavior and functioning in dogs with clinical osteoarthritis

    OpenAIRE

    Rialland, Pascale; Bichot, Sylvain; Lussier, Bertrand; Moreau, Maxim; Beaudry, Francis; del Castillo, Jérôme RE; Gauvin, Dominique; Troncy, Eric

    2013-01-01

    This study aimed to establish the effect of a diet enriched with green-lipped mussel (GLM) on pain and functional outcomes in osteoarthritic dogs. Twenty-three client-owned dogs with osteoarthritis (OA) were fed a balanced control diet for 30 d and then a GLM-enriched balanced diet for the next 60 d. We assessed peak vertical force (PVF), which is considered to be the gold standard method, at Day (D)0 (start), D30 (end of control diet), and D90 (end of GLM-enriched diet). The owners completed...

  18. Hemodynamic deterioration during extracorporeal membrane oxygenation weaning in a patient with a total artificial heart.

    Science.gov (United States)

    Hosseinian, Leila; Levin, Matthew A; Fischer, Gregory W; Anyanwu, Anelechi C; Torregrossa, Gianluca; Evans, Adam S

    2015-01-01

    The Total Artificial Heart (Syncardia, Tucson, AZ) is approved for use as a bridge-to-transplant or destination therapy in patients who have irreversible end-stage biventricular heart failure. We present a unique case, in which the inferior vena cava compression by a total artificial heart was initially masked for days by the concurrent placement of an extracorporeal membrane oxygenation cannula. This is the case of a 33-year-old man admitted to our institution with recurrent episodes of ventricular tachycardia requiring emergent total artificial heart and venovenous extracorporeal membrane oxygenation placement. This interesting scenario highlights the importance for critical care physicians to have an understanding of exact anatomical localization of a total artificial heart, extracorporeal membrane oxygenation, and their potential interactions. In total artificial heart patients with hemodynamic compromise or reduced device filling, consideration should always be given to venous inflow compression, particularly in those with smaller body surface area. Transesophageal echocardiogram is a readily available diagnostic tool that must be considered standard of care, not only in the operating room but also in the ICU, when dealing with this complex subpopulation of cardiac patients.

  19. Artificial O3 formation during fireworks

    Science.gov (United States)

    Fiedrich, M.; Kurtenbach, R.; Wiesen, P.; Kleffmann, J.

    2017-09-01

    In several previous studies emission of ozone (O3) during fireworks has been reported, which was attributed to either photolysis of molecular oxygen (O2) or nitrogen dioxide (NO2) by short/near UV radiation emitted during the high-temperature combustion of fireworks. In contrast, in the present study no O3 formation was observed using a selective O3-LOPAP instrument during the combustion of pyrotechnical material in the laboratory, while a standard O3 monitor using UV absorption showed extremely high O3 signals. The artificial O3 response of the standard O3 monitor was caused by known interferences associated with high levels of co-emitted VOCs and could also be confirmed in field measurements during New Year's Eve in the city of Wuppertal, Germany. The present results help to explain unreasonably high ozone levels documented during ambient fireworks, which are in contradiction to the fast titration of O3 by nitrogen monoxide (NO) in the night-time atmosphere.

  20. The influence on the images of computed tomography caused by the use of artificial cranial reconstructive materials

    International Nuclear Information System (INIS)

    Itokawa, Hiroshi; Moriya, Masao; Fujimoto, Michio; Nagashima, Goro; Suzuki, Ryuta; Fujimoto, Tsukasa; Yasuda, Mitsuyoshi; Kato, Kyoichi; Hirade, Tsuneo

    2008-01-01

    Various materials have been used for cranioplasty; however these materials frequently produce artifacts that appear when examined with conventional radiography. Computed tomography (CT) in particular, detects high density artifacts near artificial bones, which is manipulated by increased noise, and limits diagnostic performance. The purpose of this study was to evaluate the extent and shape of the artifacts due to artificial cranial bones and to consider CT imaging parameters necessary for accurate recognition of structures under the materials. Four different artificial bone materials were evaluated in this study: hydroxyapatite with 40% or 50% porosity, titanium plate, and hydroxyapatite-polymethylmethacrylate composite (HA-PMMA). CT scanning was performed with standard clinical settings. Sample specimens were placed on the right side, under the artificial bones, and CT was performed to evaluate specimen visibility. We compared the artifacts created by the four bone types listed above, and measured the CT, values of those materials. With ordinary scan settings, all the artificial bones revealed high-density artifact surrounding the materials, including the inability to accurately measure specimen thickness. The upper part of the specimen in contact with the artificial bones could not be distinguished from the artifact. The CT value in the medial aspect of the artificial bones increased more than the actual CT values. Of the four artificial bone materials studied, HA-PMMA produced the fewest artifacts. Description of the structures under the artificial bones can be improved by extending the window width to aproximately twice that of normal settings. (author)

  1. High-protein diet selectively reduces fat mass and improves glucose tolerance in Western-type diet-induced obese rats

    Science.gov (United States)

    Stengel, Andreas; Goebel-Stengel, Miriam; Wang, Lixin; Hu, Eugenia; Karasawa, Hiroshi; Pisegna, Joseph R.

    2013-01-01

    Obesity is an increasing health problem. Because drug treatments are limited, diets remain popular. High-protein diets (HPD) reduce body weight (BW), although the mechanisms are unclear. We investigated physiological mechanisms altered by switching diet induced obesity (DIO) rats from Western-type diet (WTD) to HPD. Male rats were fed standard (SD) or WTD (45% calories from fat). After developing DIO (50% of rats), they were switched to SD (15% calories from protein) or HPD (52% calories from protein) for up to 4 weeks. Food intake (FI), BW, body composition, glucose tolerance, insulin sensitivity, and intestinal hormone plasma levels were monitored. Rats fed WTD showed an increased FI and had a 25% greater BW gain after 9 wk compared with SD (P Diet-induced obese rats switched from WTD to HPD reduced daily FI by 30% on day 1, which lasted to day 9 (−9%) and decreased BW during the 2-wk period compared with SD/SD (P < 0.05). During these 2 wk, WTD/HPD rats lost 72% more fat mass than WTD/SD (P < 0.05), whereas lean mass was unaltered. WTD/HPD rats had lower blood glucose than WTD/SD at 30 min postglucose gavage (P < 0.05). The increase of pancreatic polypeptide and peptide YY during the 2-h dark-phase feeding was higher in WTD/HPD compared with WTD/SD (P < 0.05). These data indicate that HPD reduces BW in WTD rats, which may be related to decreased FI and the selective reduction of fat mass accompanied by improved glucose tolerance, suggesting relevant benefits of HPD in the treatment of obesity. PMID:23883680

  2. Apoptosis induced by a low-carbohydrate and high-protein diet in rat livers.

    Science.gov (United States)

    Monteiro, Maria Emília L; Xavier, Analucia R; Oliveira, Felipe L; Filho, Porphirio Js; Azeredo, Vilma B

    2016-06-14

    To determine whether high-protein, high-fat, and low-carbohydrate diets can cause lesions in rat livers. We randomly divided 20 female Wistar rats into a control diet group and an experimental diet group. Animals in the control group received an AIN-93M diet, and animals in the experimental group received an Atkins-based diet (59.46% protein, 31.77% fat, and 8.77% carbohydrate). After 8 wk, the rats were anesthetized and exsanguinated for transaminases analysis, and their livers were removed for flow cytometry, immunohistochemistry, and light microscopy studies. We expressed the data as mean ± standard deviation (SD) assuming unpaired and parametric data; we analyzed differences using the Student's t-test. Statistical significance was set at P diet group and 3.73% ± 0.50% for early apoptosis, 5.67% ± 0.72% for late apoptosis, and 3.82% ± 0.28% for non-apoptotic death in the control diet group. The mean percentage of early apoptosis was higher in the experimental diet group than in the control diet group. Immunohistochemistry for autophagy was negative in both groups. Sinusoidal dilation around the central vein and small hepatocytes was only observed in the experimental diet group, and fibrosis was not identified by hematoxylin-eosin or Trichrome Masson staining in either group. Eight weeks of an experimental diet resulted in cellular and histopathological lesions in rat livers. Apoptosis was our principal finding; elevated plasma transaminases demonstrate hepatic lesions.

  3. Diet as a system: an observational study investigating a multi-choice system of moderately restricted low-protein diets.

    Science.gov (United States)

    Piccoli, Giorgina Barbara; Nazha, Marta; Capizzi, Irene; Vigotti, Federica Neve; Scognamiglio, Stefania; Consiglio, Valentina; Mongilardi, Elena; Bilocati, Marilisa; Avagnina, Paolo; Versino, Elisabetta

    2016-12-07

    There is no single, gold-standard, low-protein diet (LPD) for CKD patients; the best compliance is probably obtained by personalization. This study tests the hypothesis that a multiple choice diet network allows patients to attain a good compliance level, and that, in an open-choice system, overall results are not dependent upon the specific diet, but upon the clinical characteristics of the patients. Observational study: Three LPD options were offered to all patients with severe or rapidly progressive CKD: vegan diets supplemented with alpha-ketoacids and essential aminoacids; protein-free food in substitution of normal bread and pasta; other (traditional, vegan non supplemented and tailored). Dialysis-free follow-up and survival were analyzed by Kaplan Meier curves according to diet, comorbidity and age. Compliance and metabolic control were estimated in 147 subjects on diet at March 2015, with recent complete data, prescribed protein intake 0.6 g/Kg/day. Protein intake was assessed by Maroni Mitch formula. Four hundreds and forty nine patients followed a LPD in December, 2007- March, 2015 (90% moderately restricted LPDs, 0.6 g/Kg/day of protein, 10% at lower targets); age (median 70 (19-97)) and comorbidity (Charlson index: 7) characterized our population as being in line with the usual CKD European population. Median e-GFR at start of the diet was 20 mL/min, 33.2% of the patients were diabetics. Baseline data differ significantly across diets: protein-free schemas are preferred by older, high-comorbidity patients (median age 76 years, Charlson index 8, GFR 20.5 mL/min, Proteinuria: 0.3 g/day), supplemented vegan diets by younger patients with lower GFR and higher proteinuria (median age 65 years, Charlson index 6, GFR 18.9 mL/min; Proteinuria: 1.2 g/day); other diets are chosen by an intermediate population (median age 71 years, Charlson index 6; GFR 22.5 mL/min; Proteinuria: 0.9 g/day); (p <0.001 for age, Charlson index, proteinuria, GFR

  4. [Influence of hypocaloric diet with addition of a vitamin-mineral complex on status of patients with obesity 1st and 2nd degrees].

    Science.gov (United States)

    Sharafetdinov, Kh Kh; Plotnikova, O A; Zykina, V V; Mal'tsev, G Iu; Sokol'nikov, A A; Kaganov, B S

    2011-01-01

    Addition of a vitamin-mineral complex (VMC) to a standard hypocaloric diet leads to a positive dynamics of antropometric characteristics in patients with obesity 1st and 2nd degrees which is comparable to effectiveness of standard dietotherapy (dietary treatment) traditionally used in complex treatment of obesity. Addition of 1,8 mg of vitamin B2 as part of VMC to a hypocaloric diet is shown to be inadequate in eradication of marginal provision of riboflavin when using diets reduced in calories.

  5. Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice

    Science.gov (United States)

    2014-01-01

    Background Diet therapies including calorie restriction, ketogenic diets, and fish-oil supplementation have been used to improve health and to treat a variety of neurological and non-neurological diseases. Methods We investigated the effects of three diets on circulating plasma metabolites (glucose and β-hydroxybutyrate), hormones (insulin and adiponectin), and lipids over a 32-day period in C57BL/6J mice. The diets evaluated included a standard rodent diet (SD), a ketogenic diet (KD), and a standard rodent diet supplemented with fish-oil (FO). Each diet was administered in either unrestricted (UR) or restricted (R) amounts to reduce body weight by 20%. Results The KD-UR increased body weight and glucose levels and promoted a hyperlipidemic profile, whereas the FO-UR decreased body weight and glucose levels and promoted a normolipidemic profile, compared to the SD-UR. When administered in restricted amounts, all three diets produced a similar plasma metabolite profile, which included decreased glucose levels and a normolipidemic profile. Linear regression analysis showed that circulating glucose most strongly predicted body weight and triglyceride levels, whereas calorie intake moderately predicted glucose levels and strongly predicted ketone body levels. Conclusions These results suggest that biomarkers of health can be improved when diets are consumed in restricted amounts, regardless of macronutrient composition. PMID:24910707

  6. Generation of artificial FASTQ files to evaluate the performance of next-generation sequencing pipelines.

    Directory of Open Access Journals (Sweden)

    Matthew Frampton

    Full Text Available Pipelines for the analysis of Next-Generation Sequencing (NGS data are generally composed of a set of different publicly available software, configured together in order to map short reads of a genome and call variants. The fidelity of pipelines is variable. We have developed ArtificialFastqGenerator, which takes a reference genome sequence as input and outputs artificial paired-end FASTQ files containing Phred quality scores. Since these artificial FASTQs are derived from the reference genome, it provides a gold-standard for read-alignment and variant-calling, thereby enabling the performance of any NGS pipeline to be evaluated. The user can customise DNA template/read length, the modelling of coverage based on GC content, whether to use real Phred base quality scores taken from existing FASTQ files, and whether to simulate sequencing errors. Detailed coverage and error summary statistics are outputted. Here we describe ArtificialFastqGenerator and illustrate its implementation in evaluating a typical bespoke NGS analysis pipeline under different experimental conditions. ArtificialFastqGenerator was released in January 2012. Source code, example files and binaries are freely available under the terms of the GNU General Public License v3.0. from https://sourceforge.net/projects/artfastqgen/.

  7. Dietary Reversal Ameliorates Short- and Long-Term Memory Deficits Induced by High-fat Diet Early in Life.

    Directory of Open Access Journals (Sweden)

    Catrina Sims-Robinson

    Full Text Available A high-fat diet (HFD, one of the major factors contributing to metabolic syndrome, which is associated with an increased risk of neurodegenerative diseases, leads to insulin resistance and cognitive impairment. It is not known whether these alterations are improved with dietary intervention. To investigate the long-term impact of a HFD on hippocampal insulin signaling and memory, C57BL6 mice were placed into one of three groups based on the diet: a standard diet (control, a HFD, or a HFD for 16 weeks and then the standard diet for 8 weeks (HF16. HFD-induced impairments in glucose tolerance and hippocampal insulin signaling occurred concurrently with deficits in both short- and long-term memory. Furthermore, these conditions were improved with dietary intervention; however, the HFD-induced decrease in insulin receptor expression in the hippocampus was not altered with dietary intervention. Our results demonstrate that memory deficits due to the consumption of a HFD at an early age are reversible.

  8. The case for low carbohydrate diets in diabetes management.

    Science.gov (United States)

    Arora, Surender K; McFarlane, Samy I

    2005-07-14

    basis. Whereas it is traditional to say that more work needs to be done, the same is true of the assumed standard low fat diets which have an ambiguous record at best. We see current trends in the national dietary recommendations as a positive sign and an appropriate move in the right direction.

  9. Exploring Diet Quality between Urban and Rural Dwelling Women of Reproductive Age.

    Science.gov (United States)

    Martin, Julie C; Moran, Lisa J; Teede, Helena J; Ranasinha, Sanjeeva; Lombard, Catherine B; Harrison, Cheryce L

    2017-06-08

    Health disparities, including weight gain and obesity exist between urban and rural dwelling women. The primary aim was to compare diet quality in urban and rural women of reproductive age, and secondary analyses of the difference in macronutrient and micronutrient intake in urban and rural women, and the predictors of diet quality. Diet quality was assessed in urban ( n = 149) and rural ( n = 394) women by a modified version of the Dietary Guideline Index (DGI) energy, macronutrient and micronutrient intake from a food frequency questionnaire (FFQ) and predictors of diet quality. Diet quality did not significantly differ between urban and rural women (mean ± standard deviation (SD), 84.8 ± 15.9 vs. 83.9 ± 16.5, p = 0.264). Rural women reported a significantly higher intake of protein, fat, saturated fat, monounsaturated fat, cholesterol and iron and a higher score in the meat and meat alternatives component of the diet quality tool in comparison to urban women. In all women, a higher diet quality was associated with higher annual household income (>$Australian dollar (AUD) 80,000 vs. urban and rural women; however, a higher macronutrient consumption pattern was potentially related to a higher lean meat intake in rural women. Women who are unemployed and on a lower income are an important target group for future dietary interventions aiming to improve diet quality.

  10. Internet Information for Patients on Cancer Diets - an Analysis of German Websites.

    Science.gov (United States)

    Herth, Natalie; Kuenzel, Ulrike; Liebl, Patrick; Keinki, Christian; Zell, Joerg; Huebner, Jutta

    2016-01-01

    In recent years, the Internet has become an important source of information for cancer patients. Various cancer diets that are publicized on the Web promise significant benefits. The aim of our study was to evaluate the quality of online patient information about cancer diets. A patient's search for 'cancer diets' on German websites was simulated using the search engine Google. The websites were evaluated utilizing a standardized instrument with formal and content aspects. An analysis of 60 websites revealed that websites from nonprofit associations as well as self-help groups offer the best content and formal ranking. Websites whose owners aim to make a profit, practices that offer cancer diet therapies, and newspapers received the poorest quality score. The majority of content provided on the Web gets published by profit-oriented content groups. The divergence between profit-driven websites offering low-quality content and the few trustworthy websites on cancer diets is enormous. The information given online about cancer diets may turn out to be a hazardous pitfall. In order to present evidence-based information about cancer diets, online information should be replenished to create a more accurate picture and give higher visibility to the right information. © 2016 S. Karger GmbH, Freiburg.

  11. Krill Oil Ameliorates Mitochondrial Dysfunctions in Rats Treated with High-Fat Diet

    Directory of Open Access Journals (Sweden)

    Alessandra Ferramosca

    2015-01-01

    Full Text Available In recent years, several studies focused their attention on the role of dietary fats in the pathogenesis of hepatic steatosis. It has been demonstrated that a high-fat diet is able to induce hyperglycemia, hyperinsulinemia, obesity, and nonalcoholic fatty liver disease. On the other hand, krill oil, a novel dietary supplement of n-3 PUFAs, has the ability to improve lipid and glucose metabolism, exerting possible protective effects against hepatic steatosis. In this study we have investigated the effects of krill oil on mitochondrial energetic metabolism in animals fed a high-fat diet. To this end, male Sprague-Dawley rats were divided into three groups and fed for 4 weeks with a standard diet (control group, a diet with 35% fat (HF group, or a high-fat diet supplemented with 2.5% krill oil (HF+KO group. The obtained results suggest that krill oil promotes the burning of fat excess introduced by the high-fat diet. This effect is obtained by stimulating mitochondrial metabolic pathways such as fatty acid oxidation, Krebs cycle, and respiratory chain complexes activity. Modulation of the expression of carrier proteins involved in mitochondrial uncoupling was also observed. Overall, krill oil counteracts the negative effects of a high-fat diet on mitochondrial energetic metabolism.

  12. Krill Oil Ameliorates Mitochondrial Dysfunctions in Rats Treated with High-Fat Diet.

    Science.gov (United States)

    Ferramosca, Alessandra; Conte, Annalea; Zara, Vincenzo

    2015-01-01

    In recent years, several studies focused their attention on the role of dietary fats in the pathogenesis of hepatic steatosis. It has been demonstrated that a high-fat diet is able to induce hyperglycemia, hyperinsulinemia, obesity, and nonalcoholic fatty liver disease. On the other hand, krill oil, a novel dietary supplement of n-3 PUFAs, has the ability to improve lipid and glucose metabolism, exerting possible protective effects against hepatic steatosis. In this study we have investigated the effects of krill oil on mitochondrial energetic metabolism in animals fed a high-fat diet. To this end, male Sprague-Dawley rats were divided into three groups and fed for 4 weeks with a standard diet (control group), a diet with 35% fat (HF group), or a high-fat diet supplemented with 2.5% krill oil (HF+KO group). The obtained results suggest that krill oil promotes the burning of fat excess introduced by the high-fat diet. This effect is obtained by stimulating mitochondrial metabolic pathways such as fatty acid oxidation, Krebs cycle, and respiratory chain complexes activity. Modulation of the expression of carrier proteins involved in mitochondrial uncoupling was also observed. Overall, krill oil counteracts the negative effects of a high-fat diet on mitochondrial energetic metabolism.

  13. A modified scout bee for artificial bee colony algorithm and its performance on optimization problems

    Directory of Open Access Journals (Sweden)

    Syahid Anuar

    2016-10-01

    Full Text Available The artificial bee colony (ABC is one of the swarm intelligence algorithms used to solve optimization problems which is inspired by the foraging behaviour of the honey bees. In this paper, artificial bee colony with the rate of change technique which models the behaviour of scout bee to improve the performance of the standard ABC in terms of exploration is introduced. The technique is called artificial bee colony rate of change (ABC-ROC because the scout bee process depends on the rate of change on the performance graph, replace the parameter limit. The performance of ABC-ROC is analysed on a set of benchmark problems and also on the effect of the parameter colony size. Furthermore, the performance of ABC-ROC is compared with the state of the art algorithms.

  14. Initial in vitro testing of a paediatric continuous-flow total artificial heart.

    Science.gov (United States)

    Fukamachi, Kiyotaka; Karimov, Jamshid H; Horvath, David J; Sunagawa, Gengo; Byram, Nicole A; Kuban, Barry D; Moazami, Nader

    2018-06-01

    Mechanical circulatory support has become standard therapy for adult patients with end-stage heart failure; however, in paediatric patients with congenital heart disease, the options for chronic mechanical circulatory support are limited to paracorporeal devices or off-label use of devices intended for implantation in adults. Congenital heart disease and cardiomyopathy often involve both the left and right ventricles; in such cases, heart transplantation, a biventricular assist device or a total artificial heart is needed to adequately sustain both pulmonary and systemic circulations. We aimed to evaluate the in vitro performance of the initial prototype of our paediatric continuous-flow total artificial heart. The paediatric continuous-flow total artificial heart pump was downsized from the adult continuous-flow total artificial heart configuration by a scale factor of 0.70 (1/3 of total volume) to enable implantation in infants. System performance of this prototype was evaluated using the continuous-flow total artificial heart mock loop set to mimic paediatric circulation. We generated maps of pump performance and atrial pressure differences over a wide range of systemic vascular resistance/pulmonary vascular resistance and pump speeds. Performance data indicated left pump flow range of 0.4-4.7 l/min at 100 mmHg delta pressure. The left/right atrial pressure difference was maintained within ±5 mmHg with systemic vascular resistance/pulmonary vascular resistance ratios between 1.4 and 35, with/without pump speed modulation, verifying expected passive self-regulation of atrial pressure balance. The paediatric continuous-flow total artificial heart prototype met design requirements for self-regulation and performance; in vivo pump performance studies are ongoing.

  15. Effects of food diets on insect development and its sensitivity to gamma radiation

    International Nuclear Information System (INIS)

    Khattak, S.U.; Azhar, A.; Shahid, M.

    2004-01-01

    Taking red flour beetle, Tribolium castaneum (Herbst), as a study case, studies on the effect of different food diets on insect development and losses and its sensitivity to gamma radiation, were conducted under controlled laboratory conditions. The results revealed that all the three major parameters (development, losses and sensitivity) varied significantly (P< 0.05) with respect to fed diet. Developmental period was highest (43.5 days) in wheat starch and lowest (22 days) in wheat flour + 5% yeast (Standard diet). A significantly highest progeny (948) was produced in barley and lowest (105.3) in wheat starch. Maximum adult weight (37.35 mg/20 adults) was recorded in sorghum and minimum (33.4) in starch. Percent weight loss was highest (21.25) in barley and lowest (8.0) in starch. Barley flour was found as the most preferred diet. Radiosensitivity in relation to diet indicated that adults reared on wheat starch were most sensitive. Comparing the dose response, insect mortality was dose, diet and post irradiation duration dependent. However, 2.5kGy proved quite lethal. No significant effect of radiation was observed on moisture and protein contents of the diets, except reducing sugars. (author)

  16. Fad diets and obesity--Part IV: Low-carbohydrate vs. low-fat diets.

    Science.gov (United States)

    Moyad, Mark A

    2005-02-01

    The first three parts of this series of articles covered the basics of some of the more popular low-carbohydrate diets, and the theories behind them. In the fourth and final part of this series, some of the more popular low-fat and low-calorie diets, such as the Ornish diet and Weight Watchers, are covered briefly. Recently, several clinical trials of longer duration that compared low-carbohydrate versus low-fat diets have been published. These studies demonstrate that some of the low-carbohydrate diets result in reduced weight in the short-term, but their ability to reduce weight long-term any better than low-fat or other diets has been questioned. Most popular or fad diets have some positive messages contained within them and some preliminary positive short-term results, but overall the compliance rates with any fad diet are very poor over the long-term. The decision to go on any diet should be made with a health professional who can monitor the patient closely.

  17. Cocoa Diet Prevents Antibody Synthesis and Modifies Lymph Node Composition and Functionality in a Rat Oral Sensitization Model

    OpenAIRE

    Camps-Bossacoma, Mariona; Abril-Gil, Mar; Salda?a-Ruiz, Sandra; Franch, ?ngels; P?rez-Cano, Francisco J.; Castell, Margarida

    2016-01-01

    Cocoa powder, a rich source of polyphenols, has shown immunomodulatory properties in both the intestinal and systemic immune compartments of rats. The aim of the current study was to establish the effect of a cocoa diet in a rat oral sensitization model and also to gain insight into the mesenteric lymph nodes (MLN) activities induced by this diet. To achieve this, three-week-old Lewis rats were fed either a standard diet or a diet with 10% cocoa and were orally sensitized with ovalbumin (OVA)...

  18. The Japanese artificial organs scene: current status.

    Science.gov (United States)

    Mitamura, Yoshinori; Murabayashi, Shun

    2005-08-01

    Artificial organs and regenerative medicine are the subjects of very active research and development (R&D) in Japan and various artificial organs are widely used in patients. Results of the R&D are presented at the annual conference of the Japanese Society for Artificial Organs (JSAO). Progress in the fields of artificial organs and regenerative medicine are reviewed annually in the Japanese Journal of Artificial Organs. The official English-language journal of JSAO, Journal of Artificial Organs, also publishes many original articles by Japanese researchers. Although the annual conference and the publications of JSAO provide the world with update information on artificial organs and regenerative medicine in Japan, the information is not always understood appropriately in the rest of the world, mainly due to language problems. This article therefore introduces the current status of artificial organs and regenerative medicine in Japan. Artificial hearts and metabolic support systems are reviewed here and other interesting areas such as regenerative medicine can be found elsewhere.

  19. Effect of High-Fat Diet upon Inflammatory Markers and Aortic Stiffening in Mice

    Directory of Open Access Journals (Sweden)

    Andre Bento Chaves Santana

    2014-01-01

    Full Text Available Changes in lifestyle such as increase in high-fat food consumption are an important cause for vascular diseases. The present study aimed to investigate the involvement of ACE and TGF-β in the aorta stiffness induced by high-fat diet. C57BL/6 male mice were divided in two groups according to their diet for 8 weeks: standard diet (ST and high-fat diet (HF. At the end of the protocol, body weight gain, adipose tissue content, serum lipids and glucose levels, and aorta morphometric and biochemical measurements were performed. Analysis of collagen fibers by picrosirius staining of aorta slices showed that HF diet promoted increase of thin (55% and thick (100% collagen fibers deposition and concomitant disorganization of these fibers orientations in the aorta vascular wall (50%. To unravel the mechanism involved, myeloperoxidase (MPO and angiotensin I converting enzyme (ACE were evaluated by protein expression and enzyme activity. HF diet increased MPO (90% and ACE (28% activities, as well as protein expression of ACE. TGF-β was also increased in aorta tissue of HF diet mice after 8 weeks. Altogether, we have observed that the HF diet-induced aortic stiffening may be associated with increased oxidative stress damage and activation of the RAS in vascular tissue.

  20. Nutrient digestibility in Arctic fox (Vulpes lagopus fed diets containing animal meals

    Directory of Open Access Journals (Sweden)

    A. Gugołek

    2010-08-01

    Full Text Available Three digestibility experiments on Arctic foxes were carried out. Control groups were fed standard diets (C1 and C2 composed of fresh or frozen animal by-products and steamed ground grain. Dry experimental diets (E1 and E2 contained animal meals, extracted meals and fat, were mixed with water prior to administration. In a preliminary experiment, the digestibility of dry diet E1 moistened with water for 15min and 24h was compared to determine the optimum moistening time during the experimental period proper. The preliminary experiment showed that moistening time had no significant effect on digestibility. In the main experiment, two independent digestibility trials were performed to compare the digestibility of diets fed to foxes during growth (C1 vs. E1 and fur development (C2 vs. E2. Better nutrient digestibility was noted for control diets, compared to experimental. The greatest differences were reported for total protein digestibility. Protein contained in meals undergoes denaturation during heat treatment, which reduces digestibility. It was found that the retention of nitrogen in relation to nitrogen digestion was higher in foxes fed experimental diets (E1 and E2.

  1. Diet and weaning age affect the growth and condition of Dover sole (Solea solea L.

    Directory of Open Access Journals (Sweden)

    2005-01-01

    Full Text Available The effect of diet type (frozen Artemia biomass and two inert diets: micro-bound [MB] and micro-extruded [ME] and two weaning ages (early weaning and late weaning, 50 and 64 days after hatching, respectively were studied in Solea solea larvae. The experiment lasted 56 and 42 days for early and late weaning, respectively. The mortality results showed the highest values for late weaning (39% in the Artemia treatment. No significant differences in mortality were observed between the inert diets. The final dry weight values were higher for late weaning than for early weaning. At both weaning ages, fish receiving the same treatments had similar tendencies for dry weight and standard length. Fish fed with MB presented significantly higher dry weight and standard length, followed by ME, while the lowest values at both weaning ages were recorded for the Artemia treatment. Similar amounts of highly unsaturated fatty acid fractions among the inert diets were reflected by the absence of significant differences in the susceptibility to oxidation (thiobarbituric acid reactive substances testing; however, significant differences were found in carbohydrate, protein and lipid contents of whole-body homogenates for both early and late weaning. At the end of the experiment no significant differences in biochemical contents were observed between the two inert diets. The results of this study suggest that weaning starting on day 50 (early weaning, using a good quality inert diet, leads to higher survival, growth and fish condition.

  2. Mediterranean diet: from a healthy diet to a sustainable dietary pattern

    Directory of Open Access Journals (Sweden)

    Sandro eDernini

    2015-05-01

    Full Text Available The notion of the Mediterranean Diet has undergone a progressive evolution over the past 60 years, from a healthy dietary pattern to a sustainable dietary pattern, in which nutrition, food, cultures, people, environment and sustainability all interact into a new model of a sustainable diet. An overview of the historical antecedents and recent increased interest in the Mediterranean diet is presented and challenges related how to improve the sustainability of the Mediterranean diet are identified. Despite its increasing popularity worldwide, adherence to the Mediterranean diet model is decreasing for multifactorial influences – life styles changes, food globalization, economic and socio-cultural factors. These changes pose serious threats to the preservation and transmission of the Mediterranean diet heritage to present and future generations. Today’s challenge is to reverse such trends. A greater focus on the Mediterranean diet's potential as a sustainable dietary pattern, instead than just on its well documented healthy benefits, can contribute to its enhancement. More cross-disciplinary studies on environmental, economic and socio-cultural, sustainability dimensions of the Mediterranean diet are foreseen as a critical need.

  3. Mediterranean Diet: From a Healthy Diet to a Sustainable Dietary Pattern.

    Science.gov (United States)

    Dernini, Sandro; Berry, Elliot M

    2015-01-01

    The notion of the Mediterranean diet has undergone a progressive evolution over the past 60 years, from a healthy dietary pattern to a sustainable dietary pattern, in which nutrition, food, cultures, people, environment, and sustainability all interact into a new model of a sustainable diet. An overview of the historical antecedents and recent increased interest in the Mediterranean diet is presented and challenges related to how to improve the sustainability of the Mediterranean diet are identified. Despite its increasing popularity worldwide, adherence to the Mediterranean diet model is decreasing for multifactorial influences - life styles changes, food globalization, economic, and socio-cultural factors. These changes pose serious threats to the preservation and transmission of the Mediterranean diet heritage to present and future generations. Today's challenge is to reverse such trends. A greater focus on the Mediterranean diet's potential as a sustainable dietary pattern, instead than just on its well-documented healthy benefits, can contribute to its enhancement. More cross-disciplinary studies on environmental, economic and socio-cultural, and sustainability dimensions of the Mediterranean diet are foreseen as a critical need.

  4. Genetic Evidence of Human Adaptation to a Cooked Diet.

    Science.gov (United States)

    Carmody, Rachel N; Dannemann, Michael; Briggs, Adrian W; Nickel, Birgit; Groopman, Emily E; Wrangham, Richard W; Kelso, Janet

    2016-04-13

    Humans have been argued to be biologically adapted to a cooked diet, but this hypothesis has not been tested at the molecular level. Here, we combine controlled feeding experiments in mice with comparative primate genomics to show that consumption of a cooked diet influences gene expression and that affected genes bear signals of positive selection in the human lineage. Liver gene expression profiles in mice fed standardized diets of meat or tuber were affected by food type and cooking, but not by caloric intake or consumer energy balance. Genes affected by cooking were highly correlated with genes known to be differentially expressed in liver between humans and other primates, and more genes in this overlap set show signals of positive selection in humans than would be expected by chance. Sequence changes in the genes under selection appear before the split between modern humans and two archaic human groups, Neandertals and Denisovans, supporting the idea that human adaptation to a cooked diet had begun by at least 275,000 years ago. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  5. Nutritional analysis and microbiological evaluation of commercially available enteral diets for cats.

    Science.gov (United States)

    Prantil, Lori R; Markovich, Jessica E; Heinze, Cailin R; Linder, Deborah E; Tams, Todd R; Freeman, Lisa M

    2016-01-01

    To determine the prevalence of nutrients less than or greater than accepted standards in commercially available enteral diets for cats, and to identify contamination incidence in enteral diets for cats. Prospective cross-sectional study. University teaching hospital. Seven commercial enteral diets for cats. Labels were evaluated to determine if diets were intended to be nutritionally complete and balanced. One diet under storage techniques partially representative of clinical conditions was sampled on days 0, 1, 3, 5, and 7 of storage for aerobic bacterial culture. All 7 diets were analyzed for key nutrients and results were compared to Association of American Feed Control Officials (AAFCO) Nutrient Profiles for Adult Cats for maintenance and National Research Council recommended allowance (NRC-RA). From label information, 4 diets were classified as complete and balanced and 3 diets were classified as not complete and balanced. All 7 diets had at least 1 nutrient less than the AAFCO minimums and the NRC-RA. The total number of nutrients less than AAFCO minimums ranged from 3 to 9 (median = 4), with iron, potassium, and manganese being the most common. Concentrations of some nutrients were undetectable. None of the samples tested had a positive aerobic culture at baseline (day 0) or on subsequent samples from days 1, 3, 5, and 7 under any storage condition. None of the diets analyzed met all of the minimum nutrient concentrations. While short-term feeding may not be of concern for an individual patient, clinicians should be aware of potential nutritional limitations when feeding enteral diets to ill or injured cats. © Veterinary Emergency and Critical Care Society 2015.

  6. Ketogenic diet

    Directory of Open Access Journals (Sweden)

    Tina Bregant

    2009-04-01

    conclusions This review traces a history of ketogenic diet, reviews its uses and side effects, and discusses possible alternatives and the diet’s possible mechanisms of action. We show how to use the diet in practice. Protocol and calculations are presented. We look toward possible future uses of the ketogenic diet, since it is efficient, under doctor’s supervison safe, but very demanding, additional treatment.

  7. Evaluation of Chemotherapeutic Agents Against Malaria, Drugs, Diet, and Biological Response Modifiers.

    Science.gov (United States)

    1991-10-29

    The oils, MCT and Miglyol , were found to be suitable placebos for fish oil. A normal chow diet (with adequate vitamin E levels) supplemented with 20...year. Co-enzyme Q10 did not act as an antioxidant like vitamin E during a malarial infection. Two oils, MCT and Miglyol , were found to be suitable...manipulation. In experiment 84 miglyol was added to a standard rodent chow diet with normal levels of vitamin E to see whether it whould interfere with the

  8. Effects of diets with different content in protein and fiber on embryotoxicity induced by experimental diabetes in rats.

    Science.gov (United States)

    Giavini, E; Airoldi, L; Broccia, M L; Roversi, G D; Prati, M

    1993-01-01

    Three groups of streptozotocin-diabetic rats were maintained during pregnancy on three hyperproteic diets with different protein contents. These differences were compensated by an equal quantity of fiber (group 1: protein 55.0%, fiber 4.5%; group 2: 45.0%, 14.0%; group 3: 35.0%, 24.0%). Three groups of nondiabetic pregnant rats were fed with the same diets and served as control. The differences of the daily protein intake among the diabetic groups were less pronounced than those expected on the basis of the diet composition, and the embryopathic effects (reduced fetal weight, increased in malformation and resorption rate) were not statistically different among the three groups of diabetic animals. The frequency of congenital malformations was higher than that observed in a previous experiment in diabetic rats maintained on a standard diet, but much lower than that observed in animals fed on a purified, fiber-poor, normoproteic diet. When the caloric intake of the diabetic rats in the different groups was determined it was found to be similar for all of them and also similar to the caloric intake of the rats given a standard nonteratogenic diet (in previous experiments), while the rats maintained on a normoproteic, teratogenic diet increased their caloric intake. These results seem to indicate that the diet composition greatly influences the intake of food and calories of pregnant diabetic rats and this may play a role in modulating the embryopathic effect of diabetes.

  9. Dieting attempts modify the association between quality of diet and obesity.

    Science.gov (United States)

    Sares-Jäske, Laura; Knekt, Paul; Lundqvist, Annamari; Heliövaara, Markku; Männistö, Satu

    2017-09-01

    Evidence on the nature of the relationship between obesity and the quality of diet remains controversial. Likewise, the possible effect of dieting attempts on this association is poorly understood. This study investigates the possible modifying effect of dieting attempts on the association between the quality of diet and obesity. The authors hypothesize that among dieters the association may be biased. The study was based on a Finnish cohort, including 5910 men and women aged 30 to 99 years, with information on diet and body mass index (BMI). Using data from a food frequency questionnaire (FFQ), an Alternate Healthy Eating Index (AHEI) applicable to the Finnish regimen was formed. Obesity was defined as a BMI ≥30 kg/m 2 . Information on dieting attempts was collected using a questionnaire. The statistical analyses were based on linear and logistic regression. We found a positive association between the quality of the diet and obesity, the relative odds of obesity between the highest and lowest quintiles of AHEI being 1.48 (95% CI, 1.20-1.82) after adjustment for confounding factors. However, in the interaction analysis of dieting attempts and AHEI, no association was observed in non-dieters (OR, 0.92; 95% CI, 0.69-1.24) but among dieters a slightly elevated risk was found (OR, 1.40; 95% CI, 0.98-1.98). We found no association between a high quality diet and obesity among non-dieters, but a tendency for a positive association in dieters. Dieting thus seems to modify the association between diet and obesity, which should be further studied using a longitudinal design. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Various ketogenic diets can differently support brain resistance against experimentally evoked seizures and seizure-induced elemental anomalies of hippocampal formation.

    Science.gov (United States)

    Chwiej, J; Patulska, A; Skoczen, A; Matusiak, K; Janeczko, K; Ciarach, M; Simon, R; Setkowicz, Z

    2017-07-01

    In this paper the influence of two different ketogenic diets (KDs) on the seizure-evoked elemental anomalies of hippocampal formation was examined. To achieve this purpose normal and pilocarpine treated rats previously fed with one of the two high fat and carbohydrate restricted diets were compared with animals on standard laboratory diet. The ketogenic ratios of the examined KDs were equal to 5:1 (KD1) and 9:1 (KD2). KD1 and standard diet fed animals presented similar patterns of seizure-evoked elemental changes in hippocampal formation. Also the analysis of behavioral data recorded after pilocarpine injection did not show any significant differences in intensity and duration of seizures between KD1 and standard diet fed animals. Higher ketogenic ratio KD2 introduced in the normal hippocampal formation prolonged changes in the accumulation of P, K, Zn and Ca. Despite this, both the intensity and duration of seizures were significantly reduced in rats fed with KD2 which suggests that its saving action on the nerve tissue may protect brain from seizure propagation. Also seizure-evoked elemental anomalies in KD2 animals were different than those observed for rats both on KD1 and standard diets. The comparison of seizure experiencing and normal rats on KD2, did not show any statistically significant differences in elemental composition of CA1 and H hippocampal areas whilst in CA3 area only Zn level changed as a result of seizures. DG was the area mostly affected by seizures in KD2 fed rats but areal densities of all examined elements increased in this hippocampal region. Copyright © 2017 Elsevier GmbH. All rights reserved.

  11. Diet induced thermogenesis

    OpenAIRE

    Westerterp KR

    2004-01-01

    Objective Daily energy expenditure consists of three components: basal metabolic rate, diet-induced thermogenesis and the energy cost of physical activity. Here, data on diet-induced thermogenesis are reviewed in relation to measuring conditions and characteristics of the diet. Methods Measuring conditions include nutritional status of the subject, physical activity and duration of the observation. Diet characteristics are energy content and macronutrient composition. Resu...

  12. Artificial neural network-aided image analysis system for cell counting.

    Science.gov (United States)

    Sjöström, P J; Frydel, B R; Wahlberg, L U

    1999-05-01

    In histological preparations containing debris and synthetic materials, it is difficult to automate cell counting using standard image analysis tools, i.e., systems that rely on boundary contours, histogram thresholding, etc. In an attempt to mimic manual cell recognition, an automated cell counter was constructed using a combination of artificial intelligence and standard image analysis methods. Artificial neural network (ANN) methods were applied on digitized microscopy fields without pre-ANN feature extraction. A three-layer feed-forward network with extensive weight sharing in the first hidden layer was employed and trained on 1,830 examples using the error back-propagation algorithm on a Power Macintosh 7300/180 desktop computer. The optimal number of hidden neurons was determined and the trained system was validated by comparison with blinded human counts. System performance at 50x and lO0x magnification was evaluated. The correlation index at 100x magnification neared person-to-person variability, while 50x magnification was not useful. The system was approximately six times faster than an experienced human. ANN-based automated cell counting in noisy histological preparations is feasible. Consistent histology and computer power are crucial for system performance. The system provides several benefits, such as speed of analysis and consistency, and frees up personnel for other tasks.

  13. Utilisation of enzyme supplemented groundnut cake based diets by ...

    African Journals Online (AJOL)

    A total of 300, twenty weeks old laying hens were used in a feeding trial to evaluate the utilisation of Peanut meal popularly called groundnut cake (GNC) based diets supplemented with enzymes by laying hens. Five dietary treatments were formulated to meet standard nutrient requirements of layers viz: 1. maize- soya ...

  14. Soft computing in artificial intelligence

    CERN Document Server

    Matson, Eric

    2014-01-01

    This book explores the concept of artificial intelligence based on knowledge-based algorithms. Given the current hardware and software technologies and artificial intelligence theories, we can think of how efficient to provide a solution, how best to implement a model and how successful to achieve it. This edition provides readers with the most recent progress and novel solutions in artificial intelligence. This book aims at presenting the research results and solutions of applications in relevance with artificial intelligence technologies. We propose to researchers and practitioners some methods to advance the intelligent systems and apply artificial intelligence to specific or general purpose. This book consists of 13 contributions that feature fuzzy (r, s)-minimal pre- and β-open sets, handling big coocurrence matrices, Xie-Beni-type fuzzy cluster validation, fuzzy c-regression models, combination of genetic algorithm and ant colony optimization, building expert system, fuzzy logic and neural network, ind...

  15. Diet-induced obesity impairs endometrial stromal cell decidualization: a potential role for impaired autophagy.

    Science.gov (United States)

    Rhee, Julie S; Saben, Jessica L; Mayer, Allyson L; Schulte, Maureen B; Asghar, Zeenat; Stephens, Claire; Chi, Maggie M-Y; Moley, Kelle H

    2016-06-01

    What effect does diet-induced obesity have on endometrial stromal cell (ESC) decidualization? Diet-induced obesity impairs ESC decidualization. Decidualization is important for successful implantation and subsequent health of the pregnancy. Compared with normal-weight women, obese women have lower pregnancy rates (both spontaneous and by assisted reproductive technology), higher rates of early pregnancy loss and poorer oocyte quality. Beginning at 6 weeks of age, female C57Bl/6J mice were fed either a high-fat/high-sugar diet (HF/HS; 58% Fat Energy/Sucrose) or a diet of standard mouse chow (CON; 13% Fat) for 12 weeks. At this point, metabolic parameters were measured. Some of the mice (n = 9 HF/HS and 9 CON) were mated with reproductively competent males, and implantation sites were assessed. Other mice (n = 11 HF/HS and 10 CON) were mated with vasectomized males, and artificial decidualization was induced. For in vitro human studies of primary ESCs, endometrial tissue was obtained via biopsy from normo-ovulatory patients without history of infertility (obese = BMI > 30 kg/m(2), n = 11 and lean = BMI treatment with cAMP and medroxyprogesterone. The level of expression of decidualization markers was assessed by RT-qPCR (mRNA) and western blotting (protein). ATP content of ESCs was measured, and levels of autophagy were assessed by western blotting of the autophagy regulators acetyl coa carboxylase (ACC) and ULK1 (Ser 317). Autophagic flux was measured by western blot of the marker LC3b-II. Mice exposed to an HF/HS diet became obese and metabolically impaired. HF/HS-exposed mice mated to reproductively competent males had smaller implantation sites in early pregnancy (P obese women than in those of normal-weight women (Ptreatment abrogated this increase. Many aspects of obesity and metabolic impairment could contribute to the decidualization defects observed in the HF/HS-exposed mice. Although our findings suggest that both autophagy and decidualization are impaired

  16. Is the Chilean Diet a Mediterranean-type Diet?

    OpenAIRE

    JAIME ROZOWSKI; ÓSCAR CASTILLO

    2004-01-01

    Food intake in Chile has changed markedly in the last decades, showing an increase in fat consumption and presently a small fruit and vegetables intake. A parallel is made between the Chilean and Mediterranean diet (mainly the one from Spain, Italy, and Greece), both currently and from 50 years ago. The main differences and similarities are based on food availability. Although Chilean diet seems to be approaching the traditional Mediterranean diet of the 60's, there is concern about changes t...

  17. Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis.

    Science.gov (United States)

    Sydor, Svenja; Sowa, Jan-Peter; Megger, Dominik A; Schlattjan, Martin; Jafoui, Sami; Wingerter, Lena; Carpinteiro, Alexander; Baba, Hideo A; Bechmann, Lars P; Sitek, Barbara; Gerken, Guido; Gulbins, Erich; Canbay, Ali

    2017-05-01

    Alterations in sphingolipid and ceramide metabolism have been associated with various diseases, including nonalcoholic fatty liver disease (NAFLD). Acid sphingomyelinase (ASM) converts the membrane lipid sphingomyelin to ceramide, thereby affecting membrane composition and domain formation. We investigated the ways in which the Asm knockout (Smpd1 -/- ) genotype affects diet-induced NAFLD. Smpd1 -/- mice and wild type controls were fed either a standard or Western diet (WD) for 6 weeks. Liver and adipose tissue morphology and mRNA expression were assessed. Quantitative proteome analysis of liver tissue was performed. Expression of selected genes was quantified in adipose and liver tissue of obese NAFLD patients. Although Smpd1 -/- mice exhibited basal steatosis with normal chow, no aggravation of NAFLD-type injury was observed with a Western diet. This protective effect was associated with the absence of adipocyte hypertrophy and the increased expression of genes associated with brown adipocyte differentiation. In white adipose tissue from obese patients with NAFLD, no expression of these genes was detectable. To further elucidate which pathways in liver tissue may be affected by Smpd1 -/- , we performed an unbiased proteome analysis. Protein expression in WD-fed Smpd1 -/- mice indicated a reduction in Rictor (mTORC2) activity; this reduction was confirmed by diminished Akt phosphorylation and altered mRNA expression of Rictor target genes. These findings indicate that the protective effect of Asm deficiency on diet-induced steatosis is conferred by alterations in adipocyte morphology and lipid metabolism and by reductions in Rictor activation.

  18. A maternal "junk-food" diet reduces sensitivity to the opioid antagonist naloxone in offspring postweaning.

    Science.gov (United States)

    Gugusheff, Jessica R; Ong, Zhi Yi; Muhlhausler, Beverly S

    2013-03-01

    Perinatal exposure to a maternal "junk-food" diet has been demonstrated to increase the preference for palatable diets in adult offspring. We aimed to determine whether this increased preference could be attributed to changes in μ-opioid receptor expression within the mesolimbic reward pathway. We report here that mRNA expression of the μ-opioid receptor in the ventral tegmental area (VTA) at weaning was 1.4-fold (males) and 1.9-fold (females) lower in offspring of junk-food (JF)-fed rat dams than in offspring of dams fed a standard rodent diet (control) (Pjunk-food diet results in early desensitization of the opioid system which may explain the increased preference for junk food in these offspring.

  19. Effect of Different Lignocellulosic Diets on Bacterial Microbiota and Hydrolytic Enzyme Activities in the Gut of the Cotton Boll Weevil (Anthonomus grandis).

    Science.gov (United States)

    Ben Guerrero, Emiliano; Soria, Marcelo; Salvador, Ricardo; Ceja-Navarro, Javier A; Campos, Eleonora; Brodie, Eoin L; Talia, Paola

    2016-01-01

    Cotton boll weevils, Anthonomus grandis , are omnivorous coleopteran that can feed on diets with different compositions, including recalcitrant lignocellulosic materials. We characterized the changes in the prokaryotic community structure and the hydrolytic activities of A. grandis larvae fed on different lignocellulosic diets. A. grandis larvae were fed on three different artificial diets: cottonseed meal (CM), Napier grass (NG) and corn stover (CS). Total DNA was extracted from the gut samples for amplification and sequencing of the V3-V4 hypervariable region of the 16S rRNA gene. Proteobacteria and Firmicutes dominated the gut microbiota followed by Actinobacteria, Spirochaetes and a small number of unclassified phyla in CM and NG microbiomes. In the CS feeding group, members of Spirochaetes were the most prevalent, followed by Proteobacteria and Firmicutes. Bray-Curtis distances showed that the samples from the CS community were clearly separated from those samples of the CM and NG diets. Gut extracts from all three diets exhibited endoglucanase, xylanase, β-glucosidase and pectinase activities. These activities were significantly affected by pH and temperature across different diets. We observed that the larvae reared on a CM showed significantly higher activities than larvae reared on NG and CS. We demonstrated that the intestinal bacterial community structure varies depending on diet composition. Diets with more variable and complex compositions, such as CS, showed higher bacterial diversity and richness than the two other diets. In spite of the detected changes in composition and diversity, we identified a core microbiome shared between the three different lignocellulosic diets. These results suggest that feeding with diets of different lignocellulosic composition could be a viable strategy to discover variants of hemicellulose and cellulose breakdown systems.

  20. Effects of a eucaloric reduced-carbohydrate diet on body composition and fat distribution in women with PCOS.

    Science.gov (United States)

    Goss, Amy M; Chandler-Laney, Paula C; Ovalle, Fernando; Goree, Laura Lee; Azziz, Ricardo; Desmond, Renee A; Wright Bates, G; Gower, Barbara A

    2014-10-01

    To determine if consumption of a reduced-carbohydrate (CHO) diet would result in preferential loss of adipose tissue under eucaloric conditions, and whether changes in adiposity were associated with changes in postprandial insulin concentration. In a crossover-diet intervention, 30 women with PCOS consumed a reduced-CHO diet (41:19:40% energy from CHO:protein:fat) for 8 weeks and a standard diet (55:18:27) for 8 weeks. Body composition by DXA and fat distribution by CT were assessed at baseline and following each diet phase. Insulin AUC was obtained from a solid meal test (SMT) during each diet phase. Participants lost 3.7% and 2.2% total fat following the reduced-CHO diet and STD diet, resp. (pLoss of fat mass following the reduced CHO diet arm was associated with lower insulin AUC (ploss of fat mass from metabolically harmful adipose depots, whereas a diet high in CHO appeared to promote repartitioning of lean mass to fat mass. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Contextual factors are associated with diet quality in youth with type 1 diabetes mellitus.

    Science.gov (United States)

    Nansel, Tonja R; Lipsky, Leah M; Liu, Aiyi; Laffel, Lori M B; Mehta, Sanjeev N

    2014-08-01

    This study examined differences in diet quality by meal type, location, and time of week in youth with type 1 diabetes mellitus. A sample of youth with type 1 diabetes mellitus (n=252; 48% female) age 8 to 18 years (mean±standard deviation=13.2±2.8 years) with diabetes duration ≥1 year (mean±standard deviation=6.3±3.4 years) completed 3-day diet records. Multilevel linear regression models tested for differences in diet quality indicators by meal type, location, and time of week (weekdays vs weekends). Participants showed greater energy intake and poorer diet quality on weekends relative to weekdays, with lower intake of fruit and vegetables, and higher intake of total and saturated fat. Differences in diet quality were seen across meal types, with higher nutrient density at breakfast and dinner than at lunch and snacks. Participants reported the highest whole-grain and lowest fat intake at breakfast, but higher added sugar than at lunch or dinner. Dinner was characterized by the highest fruit intake, lowest added sugar, and lowest glycemic load, but also the highest sodium intake. The poorest nutrient density and highest added sugar occurred during snacks. Diet quality was poorer for meals consumed away from home than those consumed at home for breakfast, dinner, and snacks. Findings regarding lunch meal location were mixed, with higher nutrient density, lower glycemic load, and less added sugar at home lunches, and lower total fat, saturated fat, and sodium at lunches away from home. Findings indicate impacts of meal type, location, and time of week on diet quality, suggesting targets for nutrition education and behavioral interventions. Copyright © 2014 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  2. An Immune-Modulating Diet in Combination with Chemotherapy Prevents Cancer Cachexia by Attenuating Systemic Inflammation in Colon 26 Tumor-Bearing Mice.

    Science.gov (United States)

    Nakamura, Kentaro; Sasayama, Akina; Takahashi, Takeshi; Yamaji, Taketo

    2015-01-01

    Cancer cachexia is characterized by muscle wasting caused partly by systemic inflammation. We previously demonstrated an immune-modulating diet (IMD), an enteral diet enriched with immunonutrition and whey-hydrolyzed peptides, to have antiinflammatory effects in some experimental models. Here, we investigated whether the IMD in combination with chemotherapy could prevent cancer cachexia in colon 26 tumor-bearing mice. Forty tumor-bearing mice were randomized into 5 groups: tumor-bearing control (TB), low dose 5-fluorouracil (5-FU) and standard diet (LF/ST), low dose 5-FU and IMD (LF/IMD), high dose 5-FU and standard diet (HF/ST) and high dose 5-FU and IMD (HF/IMD). The ST and IMD mice received a standard diet or the IMD ad libitum for 21 days. Muscle mass in the IMD mice was significantly higher than that in the ST mice. The LF/IMD in addition to the HF/ST and HF/IMD mice preserved their body and carcass weights. Plasma prostaglandin E2 levels were significantly lower in the IMD mice than in the ST mice. A combined effect was also observed in plasma interleukin-6, glucose, and vascular endothelial growth factor levels. Tumor weight was not affected by different diets. In conclusion, the IMD in combination with chemotherapy prevented cancer cachexia without suppressing chemotherapeutic efficacy.

  3. Iodine in diet

    Science.gov (United States)

    Diet - iodine ... Many months of iodine deficiency in a person's diet may cause goiter or hypothyroidism . Without enough iodine, ... and older children. Getting enough iodine in the diet may prevent a form of physical and intellectual ...

  4. Fluoride in diet

    Science.gov (United States)

    Diet - fluoride ... bones and teeth. Too much fluoride in the diet is very rare. Rarely, infants who get too ... of essential vitamins is to eat a balanced diet that contains a variety of foods from the ...

  5. Artificial Intelligence

    CERN Document Server

    Warwick, Kevin

    2011-01-01

    if AI is outside your field, or you know something of the subject and would like to know more then Artificial Intelligence: The Basics is a brilliant primer.' - Nick Smith, Engineering and Technology Magazine November 2011 Artificial Intelligence: The Basics is a concise and cutting-edge introduction to the fast moving world of AI. The author Kevin Warwick, a pioneer in the field, examines issues of what it means to be man or machine and looks at advances in robotics which have blurred the boundaries. Topics covered include: how intelligence can be defined whether machines can 'think' sensory

  6. A Comparison of Alkaline Water and Mediterranean Diet vs Proton Pump Inhibition for Treatment of Laryngopharyngeal Reflux.

    Science.gov (United States)

    Zalvan, Craig H; Hu, Shirley; Greenberg, Barbara; Geliebter, Jan

    2017-10-01

    Laryngopharyngeal reflux (LPR) is a common disorder with protean manifestations in the head and neck. In this retrospective study, we report the efficacy of a wholly dietary approach using alkaline water, a plant-based, Mediterranean-style diet, and standard reflux precautions compared with that of the traditional treatment approach of proton pump inhibition (PPI) and standard reflux precautions. To determine whether treatment with a diet-based approach with standard reflux precautions alone can improve symptoms of LPR compared with treatment with PPI and standard reflux precautions. This was a retrospective medical chart review of 2 treatment cohorts. From 2010 to 2012, 85 patients with LPR that were treated with PPI and standard reflux precautions (PS) were identified. From 2013 to 2015, 99 patients treated with alkaline water (pH >8.0), 90% plant-based, Mediterranean-style diet, and standard reflux precautions (AMS) were identified. The outcome was based on change in Reflux Symptom Index (RSI). Recorded change in the RSI after 6 weeks of treatment. Of the 184 patients identified in the PS and AMS cohorts, the median age of participants in each cohort was 60 years (95% CI, 18-82) and 57 years (95% CI, 18-93), respectively (47 [56.3%] and 61 [61.7%] were women, respectively). The percentage of patients achieving a clinically meaningful (≥6 points) reduction in RSI was 54.1% in PS-treated patients and 62.6% in AMS-treated patients (difference between the groups, 8.05; 95% CI, -5.74 to 22.76). The mean reduction in RSI was 27.2% for the PS group and 39.8% in the AMS group (difference, 12.10; 95% CI, 1.53 to 22.68). Our data suggest that the effect of PPI on the RSI based on proportion reaching a 6-point reduction in RSI is not significantly better than that of alkaline water, a plant-based, Mediterranean-style diet, and standard reflux precautions, although the difference in the 2 treatments could be clinically meaningful in favor of the dietary approach. The

  7. Postprandial Glucose Surges after Extremely Low Carbohydrate Diet in Healthy Adults.

    Science.gov (United States)

    Kanamori, Koji; Ihana-Sugiyama, Noriko; Yamamoto-Honda, Ritsuko; Nakamura, Tomoka; Sobe, Chie; Kamiya, Shigemi; Kishimoto, Miyako; Kajio, Hiroshi; Kawano, Kimiko; Noda, Mitsuhiko

    2017-09-01

    Carbohydrate-restricted diets are prevalent not only in obese people but also in the general population to maintain appropriate body weight. Here, we report that extreme carbohydrate restriction for one day affects the subsequent blood glucose levels in healthy adults. Ten subjects (median age 30.5 years, BMI 21.1 kg/m 2 , and HbA1c 5.5%), wearing with a continuous glucose monitoring device, were given isoenergetic test meals for 4 consecutive days. On day 1, day 2 (D2), and day 4 (D4), they consumed normal-carbohydrate (63-66% carbohydrate) diet, while on day 3, they took low-carbohydrate/high-fat (5% carbohydrate) diet. The daily energy intake was 2,200 kcal for males and 1,700 kcal for females. On D2 and D4, we calculated the mean 24-hr blood glucose level (MEAN/24h) and its standard deviation (SD/24h), the area under the curve (AUC) for glucose over 140 mg/dL within 4 hours after each meal (AUC/4h/140), the mean amplitude of the glycemic excursions (MAGE), the incremental AUC of 24-hr blood glucose level above the mean plus one standard deviation (iAUC/MEAN+SD). Indexes for glucose fluctuation on D4 were significantly greater than those on D2 (SD/24h; p = 0.009, MAGE; p = 0.013, AUC/4h/140 after breakfast and dinner; p = 0.006 and 0.005, and iAUC/MEAN+SD; p = 0.007). The value of MEAN/24h and AUC/4h/140 after lunch on D4 were greater than those on D2, but those differences were not statistically significant. In conclusion, consumption of low-carbohydrate/high-fat diet appears to cause higher postprandial blood glucose on subsequent normal-carbohydrate diet particularly after breakfast and dinner in healthy adults.

  8. Applications of artificial neural networks in medical science.

    Science.gov (United States)

    Patel, Jigneshkumar L; Goyal, Ramesh K

    2007-09-01

    Computer technology has been advanced tremendously and the interest has been increased for the potential use of 'Artificial Intelligence (AI)' in medicine and biological research. One of the most interesting and extensively studied branches of AI is the 'Artificial Neural Networks (ANNs)'. Basically, ANNs are the mathematical algorithms, generated by computers. ANNs learn from standard data and capture the knowledge contained in the data. Trained ANNs approach the functionality of small biological neural cluster in a very fundamental manner. They are the digitized model of biological brain and can detect complex nonlinear relationships between dependent as well as independent variables in a data where human brain may fail to detect. Nowadays, ANNs are widely used for medical applications in various disciplines of medicine especially in cardiology. ANNs have been extensively applied in diagnosis, electronic signal analysis, medical image analysis and radiology. ANNs have been used by many authors for modeling in medicine and clinical research. Applications of ANNs are increasing in pharmacoepidemiology and medical data mining. In this paper, authors have summarized various applications of ANNs in medical science.

  9. Charlas sobre inteligencia artificial

    OpenAIRE

    Álvarez Sánchez, José Ramón; Ferrández Vicente, José Manuel; Paz López, Félix de la

    2014-01-01

    Serie: Informática en Radio 3 La Inteligencia Artificial es una de las ciencias que causa mayor impacto en la sociedad, mucho más si tenemos en cuenta que cambiará el futuro de la humanidad. En España existen actualmente un nutrido grupo de equipos de investigación relacionados con las tecnologías de computación natural-artificial que aúnan sus esfuerzos a través de la RTNAC la Red Temática en Tecnologías de Computación Natural-Artificial . La UNED participa en todas sus actividades desde ...

  10. Artificial Intelligence Project

    Science.gov (United States)

    1990-01-01

    Symposium on Aritificial Intelligence and Software Engineering Working Notes, March 1989. Blumenthal, Brad, "An Architecture for Automating...Artificial Intelligence Project Final Technical Report ARO Contract: DAAG29-84-K-OGO Artificial Intelligence LaboratO"ry The University of Texas at...Austin N>.. ~ ~ JA 1/I 1991 n~~~ Austin, Texas 78712 ________k A,.tificial Intelligence Project i Final Technical Report ARO Contract: DAAG29-84-K-0060

  11. Nutrition and Diet

    Science.gov (United States)

    ... Thai HbH:Vietnamese Relevant links Living with Thalassemia NUTRITION AND EXERCISE ▶ Nutrition and DietDiet for the ... Thalassemia (for providers) Exercise for Patients with Thalassemia Nutrition and Diet Nutritional deficiencies are common in thalassemia, ...

  12. Effect of Various Diets on the Expression of Phase-I Drug Metabolizing Enzymes in Livers of Mice

    Science.gov (United States)

    Guo, Ying; Cui, Julia Yue; Lu, Hong; Klaassen, Curtis D.

    2017-01-01

    Previous studies have shown that diets can alter the metabolism of drugs; however, it is difficult to compare the effects of multiple diets on drug metabolism among different experimental settings. Phase-I related genes play a major role in the biotransformation of pro-drugs and drugs.In the current study, effects of nine diets on the mRNA expression of phase-I drug-metabolizing enzymes in livers of mice were simultaneously investigated. Compared to the AIN-93M purified diet (control), 73 of the 132 critical phase-I drug metabolizing genes were differentially regulated by at least one diet. Diet restriction produced the most number of changed genes (51), followed by the atherogenic diet (27), high-fat diet (25), standard rodent chow (21), western diet (20), high-fructose diet (5), EFA deficient diet (3), and low n-3 FA diet (1). The mRNAs of the Fmo family changed most, followed by Cyp2b and 4a subfamilies, as well as Por (From 1121 to 21-fold increase of theses mRNAs). There were 59 genes not altered by any of these diets.The present results may improve the interpretation of studies with mice and aid in determining effective and safe doses for individuals with different nutritional diets. PMID:25733028

  13. Mediterranean Diet: Choose This Heart-Healthy Diet Option

    Science.gov (United States)

    ... Lifestyle Nutrition and healthy eating The heart-healthy Mediterranean diet is a healthy eating plan based on typical ... Mediterranean-style cooking. Here's how to adopt the Mediterranean diet. By Mayo Clinic Staff If you're looking ...

  14. Beyond AI: Artificial Dreams Conference

    CERN Document Server

    Zackova, Eva; Kelemen, Jozef; Beyond Artificial Intelligence : The Disappearing Human-Machine Divide

    2015-01-01

    This book is an edited collection of chapters based on the papers presented at the conference “Beyond AI: Artificial Dreams” held in Pilsen in November 2012. The aim of the conference was to question deep-rooted ideas of artificial intelligence and cast critical reflection on methods standing at its foundations.  Artificial Dreams epitomize our controversial quest for non-biological intelligence, and therefore the contributors of this book tried to fully exploit such a controversy in their respective chapters, which resulted in an interdisciplinary dialogue between experts from engineering, natural sciences and humanities.   While pursuing the Artificial Dreams, it has become clear that it is still more and more difficult to draw a clear divide between human and machine. And therefore this book tries to portrait such an image of what lies beyond artificial intelligence: we can see the disappearing human-machine divide, a very important phenomenon of nowadays technological society, the phenomenon which i...

  15. Artificial Photosynthesis: Beyond Mimicking Nature

    International Nuclear Information System (INIS)

    Dau, Holger; Fujita, Etsuko; Sun, Licheng

    2017-01-01

    In this Editorial, Guest Editors Holger Dau, Etsuko Fujita, and Licheng Sun introduce the Special Issue of ChemSusChem on “Artificial Photosynthesis for Sustainable Fuels”. Here, they discuss the need for non-fossil based fuels, introduce both biological and artificial photosynthesis, and outline various important concepts in artificial photosynthesis, including molecular and solid-state catalysts for water oxidation and hydrogen evolution, catalytic CO 2 reduction, and photoelectrochemical systems.

  16. DASH Diet: Reducing Hypertension through Diet and Lifestyle

    Science.gov (United States)

    ... include soy beans, collard greens and calcium-fortified beverages such as almond milk. Limit Saturated Fat A DASH diet is low in saturated fats, sodium and total fat. Studies have shown that a diet low in saturated ...

  17. Low-salt diet

    Science.gov (United States)

    Low-sodium diet; Salt restriction ... control many functions. Too much sodium in your diet can be bad for you. For most people, ... you limit salt. Try to eat a balanced diet. Buy fresh vegetables and fruits whenever possible. They ...

  18. The effects of mixed algal diets on population growth, egg productivity and nutritional profiles in cyclopoid copepods (Thermocyclops hyalinus and Mesocyclops aspericornis

    Directory of Open Access Journals (Sweden)

    Kumar Vidhya

    2014-03-01

    Full Text Available This experiment was carried out to evaluate the effect of mixed algal diet on dietary profiles of copepods. The microalgae like Spirulina platensis, Chlorella vulgaris and Azolla pinnata were mass cultured in artificial medium for a period of 20 days, cells are harvested, dried, powdered and used as feed. The small freshwater cyclopoids Thermocyclops hyalinus were compared to Mesocyclops aspericornis a species of copepod genera commonly preferred by most of the fish larvae. Both species are easily maintained in culture, when fed with mixed algal diets of equal ratios (1:1:1. Biochemical composition, egg production ratios, growth performance and fatty acids profile of the two different species were analyzed after an experimental period of 15 days, all the nutritional values were found to be high and statistically variable. On the basis of biochemical composition, egg production ratio, growth performance, amino acids and fatty acids profile it is found that M. aspericornis was the suitable candidate for larval fish diets.

  19. Parallel artificial liquid membrane extraction

    DEFF Research Database (Denmark)

    Gjelstad, Astrid; Rasmussen, Knut Einar; Parmer, Marthe Petrine

    2013-01-01

    This paper reports development of a new approach towards analytical liquid-liquid-liquid membrane extraction termed parallel artificial liquid membrane extraction. A donor plate and acceptor plate create a sandwich, in which each sample (human plasma) and acceptor solution is separated by an arti......This paper reports development of a new approach towards analytical liquid-liquid-liquid membrane extraction termed parallel artificial liquid membrane extraction. A donor plate and acceptor plate create a sandwich, in which each sample (human plasma) and acceptor solution is separated...... by an artificial liquid membrane. Parallel artificial liquid membrane extraction is a modification of hollow-fiber liquid-phase microextraction, where the hollow fibers are replaced by flat membranes in a 96-well plate format....

  20. Exploring Diet Quality between Urban and Rural Dwelling Women of Reproductive Age

    Directory of Open Access Journals (Sweden)

    Julie C. Martin

    2017-06-01

    Full Text Available Health disparities, including weight gain and obesity exist between urban and rural dwelling women. The primary aim was to compare diet quality in urban and rural women of reproductive age, and secondary analyses of the difference in macronutrient and micronutrient intake in urban and rural women, and the predictors of diet quality. Diet quality was assessed in urban (n = 149 and rural (n = 394 women by a modified version of the Dietary Guideline Index (DGI energy, macronutrient and micronutrient intake from a food frequency questionnaire (FFQ and predictors of diet quality. Diet quality did not significantly differ between urban and rural women (mean ± standard deviation (SD, 84.8 ± 15.9 vs. 83.9 ± 16.5, p = 0.264. Rural women reported a significantly higher intake of protein, fat, saturated fat, monounsaturated fat, cholesterol and iron and a higher score in the meat and meat alternatives component of the diet quality tool in comparison to urban women. In all women, a higher diet quality was associated with higher annual household income (>$Australian dollar (AUD 80,000 vs. <$AUD80,000 p = 0.013 and working status (working fulltime/part-time vs. unemployed p = 0.043. Total diet quality did not differ in urban and rural women; however, a higher macronutrient consumption pattern was potentially related to a higher lean meat intake in rural women. Women who are unemployed and on a lower income are an important target group for future dietary interventions aiming to improve diet quality.

  1. Diet induced thermogenesis

    NARCIS (Netherlands)

    Westerterp, K.R.

    2004-01-01

    OBJECTIVE: Daily energy expenditure consists of three components: basal metabolic rate, diet-induced thermogenesis and the energy cost of physical activity. Here, data on diet-induced thermogenesis are reviewed in relation to measuring conditions and characteristics of the diet. METHODS: Measuring

  2. Effect of different diets on development and Radiosensitivity of Red Flour Beetle, Tribolium castaneum (Herbst)

    International Nuclear Information System (INIS)

    Khattak, S.U; Mazhar, A.; Shahid, M.

    2000-01-01

    Studies on the effect of different diets on the development and radio-sensitivity of red flour beetle, Tribolium castaneum (Herbst) were conducted under controlled laboratory conditions. The results revealed that development, losses and sensitivity varied significantly (P< 0.05) with respect to diet. Developmental period was highest (43.5 days) in wheat starch and lowest (22 days) in wheat flour + 5% yeast (Standard diet). Significantly higher progeny (948) was produced in barley and lower (105.3) in wheat starch. Maximum adult weight (37.35 mg/20 adults) was recorded in sorghum and minimum (33.4) in starch. Percent weight loss was highest (21.25 ) in barley and lowest (8.0) in starch. Barley flour was found as the best diet. Radiosensitivity in relation to diet indicated that adults reared on wheat starch were most sensitive. Comparing the dose response, insect mortality was dose and diet dependent. However, 2.5 kGy proved quite lethal. No significant effect of radiation was observed on moisture and protein contents of the diets except reducing sugars. (author)

  3. Relationship between spatial working memory performance and diet specialization in two sympatric nectar bats.

    Directory of Open Access Journals (Sweden)

    Mickaël Henry

    Full Text Available Behavioural ecologists increasingly recognise spatial memory as one the most influential cognitive traits involved in evolutionary processes. In particular, spatial working memory (SWM, i.e. the ability of animals to store temporarily useful information for current foraging tasks, determines the foraging efficiency of individuals. As a consequence, SWM also has the potential to influence competitive abilities and to affect patterns of sympatric occurrence among closely related species. The present study aims at comparing the efficiency of SWM between generalist (Glossophaga soricina and specialist (Leptonycteris yerbabuenae nectarivorous bats at flowering patches. The two species differ in diet--the generalist diet including seasonally fruits and insects with nectar and pollen while the specialist diet is dominated by nectar and pollen yearlong--and in some morphological traits--the specialist being heavier and with proportionally longer rostrum than the generalist. These bats are found sympatrically within part of their range in the Neotropics. We habituated captive individuals to feed on artificial flower patches and we used infrared video recordings to monitor their ability to remember and avoid the spatial location of flowers they emptied in previous visits in the course of 15-min foraging sequences. Experiments revealed that both species rely on SWM as their foraging success attained significantly greater values than random expectations. However, the nectar specialist L. yerbabuenae was significantly more efficient at extracting nectar (+28% in foraging success, and sustained longer foraging bouts (+27% in length of efficient foraging sequences than the generalist G. soricina. These contrasting SWM performances are discussed in relation to diet specialization and other life history traits.

  4. Artificial organs versus regenerative medicine: is it true?

    Science.gov (United States)

    Nosé, Yukihiko; Okubo, Hisashi

    2003-09-01

    Individuals engaged in the fields of artificial kidney and artificial heart have often mistakenly stated that "the era of artificial organs is over; regenerative medicine is the future." Contrarily, we do not believe artificial organs and regenerative medicine are different medical technologies. As a matter of fact, artificial organs developed during the last 50 years have been used as a bridge to regeneration. The only difference between regenerative medicine and artificial organs is that artificial organs for the bridge to regeneration promote tissue regeneration in situ, instead of outside the body (for example, vascular prostheses, neuroprostheses, bladder substitutes, skin prostheses, bone prostheses, cartilage prostheses, ligament prostheses, etc.). All of these artificial organs are successful because tissue regeneration over a man-made prosthesis is established inside the patient's body (artificial organs to support regeneration). Another usage of the group of artificial organs for the bridge to regeneration is to sustain the functions of the patient's diseased organs during the regeneration process of the body's healthy tissues and/or organs. This particular group includes artificial kidney, hepatic assist, respiratory assist, and circulatory assist. Proof of regeneration of these healthy tissues and/or organs is demonstrated in the short-term recovery of end-stage organ failure patients (artificial organs for bridge to regeneration). A third group of artificial organs for the bridge to regeneration accelerates the regenerating process of the patient's healthy tissues and organs. This group includes neurostimulators, artificial blood (red cells) blood oxygenators, and plasmapheresis devices, including hemodiafiltrators. So-called "therapeutic artificial organs" fall into this category (artificial organs to accelerate regeneration). Thus, almost all of today's artificial organs are useful in the bridge to regeneration of healthy natural tissues and organs

  5. Off-pump transapical implantation of artificial neo-chordae to correct mitral regurgitation: the TACT Trial (Transapical Artificial Chordae Tendinae) proof of concept.

    Science.gov (United States)

    Seeburger, Joerg; Rinaldi, Mauro; Nielsen, Sten Lyager; Salizzoni, Stefano; Lange, Ruediger; Schoenburg, Markus; Alfieri, Ottavio; Borger, Michael Andrew; Mohr, Friedrich Wilhelm; Aidietis, Audrius

    2014-03-11

    The goal of this study was to evaluate the safety and performance of the NeoChord DS1000 system (NeoChord, Inc., Minneapolis, Minnesota). There is an increasing interest in transcatheter mitral valve (MV) treatment. The NeoChord DS 1000 system enables off-pump beating heart transapical MV repair with implantation of artificial neo-chordae. Patients with severe mitral regurgitation (MR) due to isolated posterior prolapse were included in this TACT (Transapical Artificial Chordae Tendinae) trial. All patients were scheduled for off-pump transapical implantation of neo-chordae. Thirty patients at 7 centers were enrolled. Major adverse events included 1 death due to post-cardiotomy syndrome and concomitant sepsis and 1 minor stroke with the patient fully recovered at the 30-day follow-up visit. Additional patients experienced procedural major adverse events related to a reoperation or conversion to standard of care. Acute procedural success (placement of at least 1 neo-chord and reduction of MR from 3+ or 4+ to ≤2+) was achieved in 26 patients (86.7%). In 4 patients neo-chordae were not placed for technical and/or patient-specific reasons. These patients underwent intraoperative (3 patients) or post-operative (1 patient) standard MV repair. At 30 days, 17 patients maintained an MR grade ≤2+. Four patients who developed recurrent MR were successfully treated with open MV repair during 30-day follow-up. Results improved with experience: durable reduction in MR to ≤2+ at 30 days was achieved in 5 (33.3%) of the first 15 patients and 12 (85.7%) of the last 14 patients. Off-pump transapical implantation of artificial chordae to correct MR is technically safe and feasible; however, it yields further potential for improvement of efficacy and durability. (Safety and Performance Study of the NeoChord Device [TACT]; NCT01777815). Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  6. Effects of defaunation on fermentation characteristics and biotin balance in an artificial rumen-simulation system (RUSITEC) receiving diets with different amounts and types of cereal.

    Science.gov (United States)

    Abel, H; Schröder, B; Lebzien, P; Flachowsky, G

    2006-01-01

    Biotin is required by rumen microbes for efficient fermentation. To evaluate the role of protozoa in ruminal biotin metabolism, five diets composed of grass hay or of grass hay/cereal grain mixtures were supplied to faunated or defaunated RUSITEC fermenters. In the mixed diets, hay was replaced to 33:67 or 67:33 w/w on an air-dried basis by either wheat or maize grain in order to simulate different cellulolytic and amylolytic fermentation conditions. Defaunation increased SCFA production, whereas NH4 concentration and the release of CH4 were reduced. Biotin input declined when cereal grain was used to replace the hay. With the exception of the high-wheat treatment, defaunated fermenters yielded higher biotin outputs than faunated fermenters. The biotin balance, calculated as the difference between the total biotin output (biotin in the solid residue contained in the nylon bags after fermentation plus the biotin in the effluent) and the biotin input with the feed, was negative for all the dietary treatments apart from fermenters supplied with the high-maize diet. It was less negative or, in the case of the high-maize diets, more positive for defaunated compared with faunated fermenters. It was concluded that, under normal faunated conditions, protozoa directly utilise or indirectly affect the bacterial synthesis and/or utilisation of biotin. With diets of a high fermentation potential, as realised with the high-wheat diet, protozoa prevent the development of a bacterial population that would utilise high or synthesise low amounts of biotin.

  7. How the Organic Food System Supports Sustainable Diets and Translates These into Practice.

    Science.gov (United States)

    Strassner, Carola; Cavoski, Ivana; Di Cagno, Raffaella; Kahl, Johannes; Kesse-Guyot, Emmanuelle; Lairon, Denis; Lampkin, Nicolas; Løes, Anne-Kristin; Matt, Darja; Niggli, Urs; Paoletti, Flavio; Pehme, Sirli; Rembiałkowska, Ewa; Schader, Christian; Stolze, Matthias

    2015-01-01

    Organic production and consumption provide a delineated food system that can be explored for its potential contribution to sustainable diets. While organic agriculture improves the sustainability performance on the production side, critical reflections are made on how organic consumption patterns, understood as the practice of people consuming significant amounts of organic produce, may also be taken as an example for sustainable food consumption. The consumption patterns of regular organic consumers seem to be close to the sustainable diet concept of FAO. Certain organic-related measures might therefore be useful in the sustainability assessment of diets, e.g., organic production and organic consumption. Since diets play a central role in shaping food systems and food systems shape diets, the role of organic consumption emerges as an essential topic to be addressed. This role may be based on four important organic achievements: organic agriculture and food production has a definition, well-established principles, public standards, and useful metrics. By 2015, data for organic production and consumption are recorded annually from more than 160 countries, and regulations are in force in more than 80 countries or regions. The organic food system puts the land (agri-cultura) back into the diet; it is the land from which the diet in toto is shaped. Therefore, the organic food system provides essential components of a sustainable diet.

  8. How the Organic Food System Supports Sustainable Diets and Translates These into Practice

    Science.gov (United States)

    Strassner, Carola; Cavoski, Ivana; Di Cagno, Raffaella; Kahl, Johannes; Kesse-Guyot, Emmanuelle; Lairon, Denis; Lampkin, Nicolas; Løes, Anne-Kristin; Matt, Darja; Niggli, Urs; Paoletti, Flavio; Pehme, Sirli; Rembiałkowska, Ewa; Schader, Christian; Stolze, Matthias

    2015-01-01

    Organic production and consumption provide a delineated food system that can be explored for its potential contribution to sustainable diets. While organic agriculture improves the sustainability performance on the production side, critical reflections are made on how organic consumption patterns, understood as the practice of people consuming significant amounts of organic produce, may also be taken as an example for sustainable food consumption. The consumption patterns of regular organic consumers seem to be close to the sustainable diet concept of FAO. Certain organic-related measures might therefore be useful in the sustainability assessment of diets, e.g., organic production and organic consumption. Since diets play a central role in shaping food systems and food systems shape diets, the role of organic consumption emerges as an essential topic to be addressed. This role may be based on four important organic achievements: organic agriculture and food production has a definition, well-established principles, public standards, and useful metrics. By 2015, data for organic production and consumption are recorded annually from more than 160 countries, and regulations are in force in more than 80 countries or regions. The organic food system puts the land (agri-cultura) back into the diet; it is the land from which the diet in toto is shaped. Therefore, the organic food system provides essential components of a sustainable diet. PMID:26176912

  9. Artificial Intelligence in Space Platforms.

    Science.gov (United States)

    1984-12-01

    computer algorithms, there still appears to be a need for Artificial Inteligence techniques in the navigation area. The reason is that navigaion, in...RD-RI32 679 ARTIFICIAL INTELLIGENCE IN SPACE PLRTFORNSMU AIR FORCE 1/𔃼 INST OF TECH WRIGHT-PRTTERSON AFB OH SCHOOL OF ENGINEERING M A WRIGHT DEC 94...i4 Preface The purpose of this study was to analyze the feasibility of implementing Artificial Intelligence techniques to increase autonomy for

  10. Trimaran Resistance Artificial Neural Network

    Science.gov (United States)

    2011-01-01

    11th International Conference on Fast Sea Transportation FAST 2011, Honolulu, Hawaii, USA, September 2011 Trimaran Resistance Artificial Neural Network Richard...Trimaran Resistance Artificial Neural Network 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e... Artificial Neural Network and is restricted to the center and side-hull configurations tested. The value in the parametric model is that it is able to

  11. Artificial Intelligence and Moral intelligence

    OpenAIRE

    Laura Pana

    2008-01-01

    We discuss the thesis that the implementation of a moral code in the behaviour of artificial intelligent systems needs a specific form of human and artificial intelligence, not just an abstract intelligence. We present intelligence as a system with an internal structure and the structural levels of the moral system, as well as certain characteristics of artificial intelligent agents which can/must be treated as 1- individual entities (with a complex, specialized, autonomous or selfdetermined,...

  12. Artificial Intelligence and Economic Theories

    OpenAIRE

    Marwala, Tshilidzi; Hurwitz, Evan

    2017-01-01

    The advent of artificial intelligence has changed many disciplines such as engineering, social science and economics. Artificial intelligence is a computational technique which is inspired by natural intelligence such as the swarming of birds, the working of the brain and the pathfinding of the ants. These techniques have impact on economic theories. This book studies the impact of artificial intelligence on economic theories, a subject that has not been extensively studied. The theories that...

  13. Internet advertising of artificial tanning in Australia.

    Science.gov (United States)

    Team, Victoria; Markovic, Milica

    2006-08-01

    Artificial tanning, defined as deliberate exposure to ultraviolet rays produced by artificial tanning devices, is a new and emerging public health issue in Australia and globally. Epidemiological research suggests that artificial tanning may contribute to the incidence of melanoma, nonmelanoma skin cancer as well as other health problems. Given that Australia has a high incidence of skin cancer, we have undertaken a study to explore how artificial tanning has been promoted to its users. The aim was to analyze the completeness and accuracy of information about artificial tanning. A content analysis of web sites of tanning salons and distributors of tanning equipment in Australia was conducted. A total of 22 web sites were analyzed. None of the solarium operators or distributors of equipment provided full information about the risks of artificial tanning. Fifty-nine percent of web advertisements had no information and 41% provided only partial information regarding the risks of artificial tanning. Pictures with the image of bronze-tanned bodies, predominantly women, were used by all web advertisers. In light of the success of sun-safety campaigns in Australia, the findings of future epidemiological research on the prevalence of artificial tanning and sociological and anthropological research on why people utilize artificial tanning should be a basis for developing effective targeted health promotion on the elimination of artificial tanning in the country.

  14. Effect of a low-carbohydrate diet on respiratory quotient of infants with chronic lung disease.

    Science.gov (United States)

    Suteerojntrakool, Orapa; Sanguanrungsirikul, Sompol; Sritippayawan, Suchada; Jantarabenjakul, Watsamon; Sirimongkol, Pathama; Chomtho, Sirinuch

    2015-01-01

    To compare the respiratory quotient in infants with chronic lung disease before and after receiving a modular diet with slightly lower carbohydrate content. Infants with chronic lung disease from the King Chulalongkorn Memorial Hospital were enrolled and assessed for nutritional status, severity of chronic lung disease and dietary intake. Indirect calorimetry was performed using a custom-made airtight canopy with O2 and CO2 sensors. Respiratory quotient (RQ) was calculated from VCO2/VO2 during the period they were fed low carbohydrates (37% of total calories) for at least 24 hours vs. a standard diet (47% carbohydrate). These two formulas were similar in terms of caloric density and protein content. Each patient received at least 100-150 kcal/ kg/day during the study period. Respiratory quotients of the same patient receiving the two diets were compared by using Wilcoxon signed-rank test. A total of 14 patients (median age 7 months, range 1-26 months) were recruited. Twelve children had weight for age Z-score below-2SD. Their median weight for age Z-score, length for age Z-score and weight for length Z-score were -2.89, -3.08 and -1.24, respectively. The median RQ measured during the low carbohydrate diet was 0.96 (interquartile range 0.95-0.97), significantly lower than the median RQ during the standard diet, which was 1.04 (0.97-1.10). However, the respiratory rate revealed no significant difference. Two participants with underlying gastroesophageal reflux disease showed higher RQ after low carbohydrate formula feeding, which might be a result of hypersecretion due to its high fat content. Diet with slightly lower carbohydrate content can reduce the RQ in infants with chronic lung disease compared to the standard enteral formula. A 10-percent reduction of carbohydrate content may provide a sizeable effect in this group of patients. Nevertheless, the clinical significance of this finding requires further investigation.

  15. Diet & Nutrition

    Science.gov (United States)

    ... Nutrition Share this page Facebook Twitter Email Diet & Nutrition Eating healthy to take charge of your health. Shelly Diagnosed in 2006 Diet & Nutrition Take Control of Your Weight Portion Control Low ...

  16. High fat, low carbohydrate diet limit fear and aggression in Göttingen minipigs.

    Directory of Open Access Journals (Sweden)

    Annika Maria Juul Haagensen

    Full Text Available High fat, low carbohydrate diets have become popular, as short-term studies show that such diets are effective for reducing body weight, and lowering the risk of diabetes and cardiovascular disease. There is growing evidence from both humans and other animals that diet affects behaviour and intake of fat has been linked, positively and negatively, with traits such as exploration, social interaction, anxiety and fear. Animal models with high translational value can help provide relevant and important information in elucidating potential effects of high fat, low carbohydrate diets on human behaviour. Twenty four young, male Göttingen minipigs were fed either a high fat/cholesterol, low carbohydrate diet or a low fat, high carbohydrate/sucrose diet in contrast to a standard low fat, high carbohydrate minipig diet. Spontaneous behaviour was observed through video recordings of home pens and test-related behaviours were recorded during tests involving animal-human contact and reaction towards a novel object. We showed that the minipigs fed a high fat/cholesterol, low carbohydrate diet were less aggressive, showed more non-agonistic social contact and had fewer and less severe skin lesions and were less fearful of a novel object than minipigs fed low fat, high carbohydrate diets. These results found in a porcine model could have important implications for general health and wellbeing of humans and show the potential for using dietary manipulations to reduce aggression in human society.

  17. Differences in predators of artificial and real songbirds nests: Evidence of bias in artificial nest studies

    Science.gov (United States)

    Frank R. Thompson; Dirk E. Burhans

    2004-01-01

    In the past two decades, many researchers have used artificial nest to measure relative rates of nest predation. Recent comparisons show that real and artificial nests may not be depredated at the same rate, but no one has examined the mechanisms underlying these patterns. We determined differences in predator-specific predation rates of real and artificial nests. we...

  18. Research on Standard and Automatic Judgment of Press-fit Curve of Locomotive Wheel-set Based on AAR Standard

    Science.gov (United States)

    Lu, Jun; Xiao, Jun; Gao, Dong Jun; Zong, Shu Yu; Li, Zhu

    2018-03-01

    In the production of the Association of American Railroads (AAR) locomotive wheel-set, the press-fit curve is the most important basis for the reliability of wheel-set assembly. In the past, Most of production enterprises mainly use artificial detection methods to determine the quality of assembly. There are cases of miscarriage of justice appear. For this reason, the research on the standard is carried out. And the automatic judgment of press-fit curve is analysed and designed, so as to provide guidance for the locomotive wheel-set production based on AAR standard.

  19. The effects of various diets on glycemic outcomes during pregnancy: A systematic review and network meta-analysis.

    Directory of Open Access Journals (Sweden)

    Vanessa Ha

    Full Text Available Evidence to support dietary modifications to improve glycemia during pregnancy is limited, and the benefits of diet beyond limiting gestational weight gain is unclear. Therefore, a systematic review and network meta-analysis of randomized trials was conducted to compare the effects of various common diets, stratified by the addition of gestational weight gain advice, on fasting glucose and insulin, hemoglobin A1c (HbA1c, and homeostatic model assessment for insulin resistance (HOMA-IR in pregnant women.MEDLINE, EMBASE, Cochrane database, and reference lists of published studies were searched through April 2017. Randomized trials directly comparing two or more diets for ≥2-weeks were eligible. Bayesian network meta-analysis was performed for fasting glucose. Owing to a lack of similar dietary comparisons, a standard pairwise meta-analysis for the other glycemic outcomes was performed. The certainty of the pooled effect estimates was assessed using the GRADE tool.Twenty-one trials (1,865 participants were included. In general, when given alongside gestational weight gain advice, fasting glucose improved in most diets compared to diets that gave gestational weight gain advice only. However, fasting glucose increased in high unsaturated or monounsaturated fatty acids diets. In the absence of gestational weight gain advice, fasting glucose improved in DASH-style diets compared to standard of care. Although most were non-significant, similar trends were observed for these same diets for the other glycemic outcomes. Dietary comparisons ranged from moderate to very low in quality of evidence.Alongside with gestational weight gain advice, most diets, with the exception of a high unsaturated or a high monounsaturated fatty acid diet, demonstrated a fasting glucose improvement compared with gestational weight gain advice only. When gestational weight gain advice was not given, the DASH-style diet appeared optimal on fasting glucose. However, a small

  20. The effects of various diets on glycemic outcomes during pregnancy: A systematic review and network meta-analysis

    Science.gov (United States)

    Ha, Vanessa; Bonner, Ashley J.; Jadoo, Jaynendr K.; Beyene, Joseph; Anand, Sonia S.

    2017-01-01

    Aims Evidence to support dietary modifications to improve glycemia during pregnancy is limited, and the benefits of diet beyond limiting gestational weight gain is unclear. Therefore, a systematic review and network meta-analysis of randomized trials was conducted to compare the effects of various common diets, stratified by the addition of gestational weight gain advice, on fasting glucose and insulin, hemoglobin A1c (HbA1c), and homeostatic model assessment for insulin resistance (HOMA-IR) in pregnant women. Methods MEDLINE, EMBASE, Cochrane database, and reference lists of published studies were searched through April 2017. Randomized trials directly comparing two or more diets for ≥2-weeks were eligible. Bayesian network meta-analysis was performed for fasting glucose. Owing to a lack of similar dietary comparisons, a standard pairwise meta-analysis for the other glycemic outcomes was performed. The certainty of the pooled effect estimates was assessed using the GRADE tool. Results Twenty-one trials (1,865 participants) were included. In general, when given alongside gestational weight gain advice, fasting glucose improved in most diets compared to diets that gave gestational weight gain advice only. However, fasting glucose increased in high unsaturated or monounsaturated fatty acids diets. In the absence of gestational weight gain advice, fasting glucose improved in DASH-style diets compared to standard of care. Although most were non-significant, similar trends were observed for these same diets for the other glycemic outcomes. Dietary comparisons ranged from moderate to very low in quality of evidence. Conclusion/Interpretation Alongside with gestational weight gain advice, most diets, with the exception of a high unsaturated or a high monounsaturated fatty acid diet, demonstrated a fasting glucose improvement compared with gestational weight gain advice only. When gestational weight gain advice was not given, the DASH-style diet appeared optimal on

  1. Diet choice patterns in rodents depend on novelty of the diet, exercise, species, and sex.

    Science.gov (United States)

    Yang, Tiffany; Xu, Wei-Jie; York, Haley; Liang, Nu-Chu

    2017-07-01

    Prolonged consumption of a palatable, high fat (HF) diet paired with a lack of physical activity can exacerbate the development of obesity. Exercise can facilitate the maintenance of a healthy body weight, possibly though mediating changes in diet preference. Using a two-diet choice and wheel running (WR) paradigm, our laboratory previously demonstrated that WR induces HF diet avoidance with different persistency in male and female rats when HF diet and WR are introduced simultaneously. The aims of this study were to examine whether this behavior is species dependent and to what extent the novelty of the diet affects WR induced HF diet avoidance. Experiment 1 utilized male C57BL6 mice in a two-diet choice and WR paradigm. Results show that all mice preferred HF to chow diet regardless of exercise and the order in which exercise and HF diet were presented. Experiment 2A (diet novelty) utilized Sprague-Dawley rats that were first habituated to a 45% HF diet prior to the simultaneous introduction of WR and a novel high-carbohydrate, low-fat (DK) diet. All rats avoided the novel high-carbohydrate diet and neither male nor female wheel running rats exhibited reduction in HF diet intake or HF diet avoidance. After all rats were returned to a sedentary condition, female rats consumed significantly more of the DK diet than the male rats. In Experiment 2B (diet familiarity), rats remained sedentary and were re-habituated to the DK diet until intake stabilized. Subsequently, a 60% HF diet was introduced for all rats and for running rats, access to the running wheels were provided simultaneously. Consistent with our previous findings, HF diet intake and preference was significantly reduced in all wheel running rats. These data suggest that exercise induced HF diet avoidance is affected by species and the novelty of the diet. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Increased susceptibility to diet-induced obesity in histamine-deficient mice

    DEFF Research Database (Denmark)

    Jørgensen, Emilie A; Vogelsang, Thomas W; Knigge, Ulrich

    2006-01-01

    in the development of high-fat diet (HFD)-induced obesity. METHODS: Histamine-deficient histidine decarboxylase knock-out (HDC-KO) mice and C57BL/6J wild-type (WT) mice were given either a standard diet (STD) or HFD for 8 weeks. Body weight, 24-hour caloric intake, epididymal adipose tissue size, plasma leptin...... weeks, whereas a significant difference in body weight gain was first observed after 5 weeks in WT mice. After 8 weeks 24-hour caloric intake was significantly lower in HFD- than in STD-fed WT mice. In HDC-KO mice no difference in caloric intake was observed between HFD- and STD-fed mice. After 8 weeks...

  3. Voluntary running of defined distances reduces body adiposity and its associated inflammation in C57BL/6 mice fed a high-fat diet.

    Science.gov (United States)

    Yan, Lin; Sundaram, Sneha; Nielsen, Forrest H

    2017-11-01

    This study investigated the effect of voluntary running of defined distances on body adiposity in male C57BL/6 mice fed a high-fat diet. Mice were assigned to 6 groups and fed a standard AIN93G diet (sedentary) or a modified high-fat AIN93G diet (sedentary; unrestricted running; or 75%, 50%, or 25% of unrestricted running) for 12 weeks. The average running distance was 8.3, 6.3, 4.2, and 2.1 km/day for the unrestricted, 75%, 50%, and 25% of unrestricted runners, respectively. Body adiposity was 46% higher in sedentary mice when fed the high-fat diet instead of the standard diet. Running decreased adiposity in mice fed the high-fat diet in a dose-dependent manner but with no significant difference between sedentary mice and those running 2.1 km/day. In sedentary mice, the high-fat instead of the standard diet increased insulin resistance, hepatic triacylglycerides, and adipose and plasma concentrations of leptin and monocyte chemotactic protein-1 (MCP-1). Running reduced these variables in a dose-dependent manner. Adipose adiponectin was lowest in sedentary mice fed the high-fat diet; running raised adiponectin in both adipose tissue and plasma. Running 8.3 and 6.3 km/day had the greatest, but similar, effects on the aforementioned variables. Running 2.1 km/day did not affect these variables except, when compared with sedentariness, it significantly decreased MCP-1. The findings showed that running 6.3 kg/day was optimal for reducing adiposity and associated inflammation that was increased in mice by feeding a high-fat diet. The findings suggest that voluntary running of defined distances may counteract the obesogenic effects of a high-fat diet.

  4. Creation and Initial Validation of the International Dysphagia Diet Standardisation Initiative Functional Diet Scale.

    Science.gov (United States)

    Steele, Catriona M; Namasivayam-MacDonald, Ashwini M; Guida, Brittany T; Cichero, Julie A; Duivestein, Janice; Hanson, Ben; Lam, Peter; Riquelme, Luis F

    2018-05-01

    To assess consensual validity, interrater reliability, and criterion validity of the International Dysphagia Diet Standardisation Initiative Functional Diet Scale, a new functional outcome scale intended to capture the severity of oropharyngeal dysphagia, as represented by the degree of diet texture restriction recommended for the patient. Participants assigned International Dysphagia Diet Standardisation Initiative Functional Diet Scale scores to 16 clinical cases. Consensual validity was measured against reference scores determined by an author reference panel. Interrater reliability was measured overall and across quartile subsets of the dataset. Criterion validity was evaluated versus Functional Oral Intake Scale (FOIS) scores assigned by survey respondents to the same case scenarios. Feedback was requested regarding ease and likelihood of use. Web-based survey. Respondents (N=170) from 29 countries. Not applicable. Consensual validity (percent agreement and Kendall τ), criterion validity (Spearman rank correlation), and interrater reliability (Kendall concordance and intraclass coefficients). The International Dysphagia Diet Standardisation Initiative Functional Diet Scale showed strong consensual validity, criterion validity, and interrater reliability. Scenarios involving liquid-only diets, transition from nonoral feeding, or trial diet advances in therapy showed the poorest consensus, indicating a need for clear instructions on how to score these situations. The International Dysphagia Diet Standardisation Initiative Functional Diet Scale showed greater sensitivity than the FOIS to specific changes in diet. Most (>70%) respondents indicated enthusiasm for implementing the International Dysphagia Diet Standardisation Initiative Functional Diet Scale. This initial validation study suggests that the International Dysphagia Diet Standardisation Initiative Functional Diet Scale has strong consensual and criterion validity and can be used reliably by clinicians

  5. CALCULATION AND EXPERIMENTAL ESTIMATION OF RESULTS OF ELECTRO-THERMAL ACTION OF RATIONED BY THE INTERNATIONAL STANDARD IEC 62305-1-2010 IMPULSE CURRENT OF SHORT BLOW OF ARTIFICIAL LIGHTNING ON THE THIN-WALLED COVERAGE FROM STAINLESS STEEL

    Directory of Open Access Journals (Sweden)

    M. I. Baranov

    2017-03-01

    Full Text Available Purpose. Calculation and experimental researches of electro-thermal resistibility of the pre-production thin-walled sheet models of outward roof of height technical buildings from stainless steel are easily soiled 12Х18Н10Т to direct action on them rationed by the International Standard IEC 62305-1-2010 aperiodic impulse of current of short bow of artificial lightning of temporal form 10/350 μs with the proper admittances on his peak-temporal parameters (PTP. Methodology. Electrophysics bases of technique of high voltage and large impulsive currents (LIC, and also scientific and technical bases of planning of high-voltage impulsive devices and measuring methods in them LIC with followings below extreme PTP: amplitude of impulse of current of ImL=200 кА (with admittance ±10 %; integral of action of impulse of current of JL=10·106 A2·s (with admittance ±35 %; %; duration of wavefront current of T1=10 μs (with admittance ±20 %; time, proper amplitude of impulse of current of ImL, tmL≤24 μs (with admittance ±20 %; duration of flowing of impulse of current of T2=350 μs (with admittance ±10 %. Results. The results of evaluation calculation and experimental researches of electro-thermal resistibility of the indicated pre-production sheet models are resulted measuring in the plan of 0,5 x 0,5 m from stainless steel are easily soiled the 12Х18Н10Т thickness of 1 mm to action on them of aperiodic impulse of current of short blow of artificial lightning with rationed PTP on the requirements of the International Standard IEC 62305-1-2010. In high current experiments amplitude of ImL of the aperiodic rationed impulse of current of artificial lightning of temporal form of T1/T2=15 μs/315 μs changed in the range of (100-184 кА. The integral of action of JL of impulse of current for I-IV of levels of protection of lightning of technical objects (TO numeral made from 2,32·106 А2·s to 7,88·106 А2·s, and the flowing through the

  6. Alternate-Day High-Fat Diet Induces an Increase in Mitochondrial Enzyme Activities and Protein Content in Rat Skeletal Muscle.

    Science.gov (United States)

    Li, Xi; Higashida, Kazuhiko; Kawamura, Takuji; Higuchi, Mitsuru

    2016-04-06

    Long-term high-fat diet increases muscle mitochondrial enzyme activity and endurance performance. However, excessive calorie intake causes intra-abdominal fat accumulation and metabolic syndrome. The purpose of this study was to investigate the effect of an alternating day high-fat diet on muscle mitochondrial enzyme activities, protein content, and intra-abdominal fat mass in rats. Male Wistar rats were given a standard chow diet (CON), high-fat diet (HFD), or alternate-day high-fat diet (ALT) for 4 weeks. Rats in the ALT group were fed a high-fat diet and standard chow every other day for 4 weeks. After the dietary intervention, mitochondrial enzyme activities and protein content in skeletal muscle were measured. Although body weight did not differ among groups, the epididymal fat mass in the HFD group was higher than those of the CON and ALT groups. Citrate synthase and beta-hydroxyacyl CoA dehydrogenase activities in the plantaris muscle of rats in HFD and ALT were significantly higher than that in CON rats, whereas there was no difference between HFD and ALT groups. No significant difference was observed in muscle glycogen concentration or glucose transporter-4 protein content among the three groups. These results suggest that an alternate-day high-fat diet induces increases in mitochondrial enzyme activities and protein content in rat skeletal muscle without intra-abdominal fat accumulation.

  7. Replacing corn with pearl millet (raw and sprouted) with and without enzyme in chickens' diet.

    Science.gov (United States)

    Afsharmanesh, M; Ghorbani, N; Mehdipour, Z

    2016-04-01

    An experiment was conducted to compare a commercial corn-soya bean meal diet with a pearl millet (raw and sprouted) diet containing less soya bean meal, alone or in combination with exogenous enzyme, on growth performance and ileal villus development of chicks. Two-hundred-and-forty-one-day-old male broilers (10/pen) were randomly allocated to one of the following dietary treatments: (i) a standard corn-soya bean meal control diet (CTL); (ii) a raw pearl millet-soya bean meal diet (PM); (iii) a sprouted pearl millet-soya bean meal diet (SPM); (iv) CTL + exogenous enzymes (CE); (v) PM + exogenous enzymes (PE); and (vi) SPM + exogenous enzymes (SPE) with four replicate pens/treatment. Body weight of birds at day 21 did not differ between those fed the CTL, and SPM and PE diets. In comparison with feeding broilers the CTL diet, feeding the PE and SPM diets caused significant decrease in feed intake, but with equivalent growth and feed efficiency. However, at day 21, feed conversion ratio did not differ between birds fed the CTL diet and those fed the PM, PE and SPM diets. At day 21, broilers fed the PM and PE diets had longer villi (p diet. At day 21, villi width was reduced (p diet. It is concluded that, in comparison with corn, broiler diets formulated with sprouted pearl millet or pearl millet with enzyme require less soya bean meal and can be used to improve growth performance traits and villus development. Journal of Animal Physiology and Animal Nutrition © 2015 Blackwell Verlag GmbH.

  8. Short-term blueberry-enriched diet prevents and reverses object recognition memory loss in aging rats.

    Science.gov (United States)

    Malin, David H; Lee, David R; Goyarzu, Pilar; Chang, Yu-Hsuan; Ennis, Lalanya J; Beckett, Elizabeth; Shukitt-Hale, Barbara; Joseph, James A

    2011-03-01

    Previously, 4 mo of a blueberry-enriched (BB) antioxidant diet prevented impaired object recognition memory in aging rats. Experiment 1 determined whether 1- and 2-mo BB diets would have a similar effect and whether the benefits would disappear promptly after terminating the diets. Experiment 2 determined whether a 1-mo BB diet could subsequently reverse existing object memory impairment in aging rats. In experiment 1, Fischer-344 rats were maintained on an appropriate control diet or on 1 or 2 mo of the BB diet before testing object memory at 19 mo postnatally. In experiment 2, rats were tested for object recognition memory at 19 mo and again at 20 mo after 1 mo of maintenance on a 2% BB or control diet. In experiment 1, the control group performed no better than chance, whereas the 1- and 2-mo BB diet groups performed similarly and significantly better than controls. The 2-mo BB-diet group, but not the 1-mo group, maintained its performance over a subsequent month on a standard laboratory diet. In experiment 2, the 19-mo-old rats performed near chance. At 20 mo of age, the rats subsequently maintained on the BB diet significantly increased their object memory scores, whereas the control diet group exhibited a non-significant decline. The change in object memory scores differed significantly between the two diet groups. These results suggest that a considerable degree of age-related object memory decline can be prevented and reversed by brief maintenance on BB diets. Copyright © 2011 Elsevier Inc. All rights reserved.

  9. Blastocysts production and collection in albino Syrian hamster using superovulation and intrauterine artificial insemination in non-breeding season

    Directory of Open Access Journals (Sweden)

    A. Amiri Divani

    2017-06-01

    Full Text Available In vivo blastocyst production and collection using superovulation and intrauterine insemination was established in albino Syrian hamsters. Twenty female albino hamsters were injected pregnant mare serum gonadotropin (PMSG, 25 IU in non-breeding season and 48 h or 56 h later, 25 IU of human chorionic gonadotropin (hCG were injected. Both groups were divided into two subgroups of natural mating and artificial insemination. The former group was mated with a fertile male (1 male for 2 fe-males after hCG injection and in the next morning, the hamsters with vaginal plug were regarded as pregnant. In the artificial insemination group, intrauterine artificial insemination of 1×108 sperms was done 12 h after hCG injection. Blastocysts were counted at 3.5 days after mating or insemination. However, 48 h and 56 h hCG and natural mating and 48 h hCG and artificial insemination were without blastocyst; however the method of 56 h hCG and artificial insemination produced of 15±5 (mean and standard deviation blastocysts in each albino hamster in the winter.

  10. Mediterranean Diet: From a Healthy Diet to a Sustainable Dietary Pattern

    OpenAIRE

    Dernini, Sandro; Berry, Elliot M.

    2015-01-01

    The notion of the Mediterranean diet has undergone a progressive evolution over the past 60 years, from a healthy dietary pattern to a sustainable dietary pattern, in which nutrition, food, cultures, people, environment, and sustainability all interact into a new model of a sustainable diet. An overview of the historical antecedents and recent increased interest in the Mediterranean diet is presented and challenges related to how to improve the sustainability of the Mediterranean diet are ide...

  11. Incontinencia urinaria post-prostatectomía: El esfinter artificial

    OpenAIRE

    Rodríguez Escobar, Fernando; Arañó Bertrán, Pedro

    2009-01-01

    El esfínter artificial (EA) es actualmente el tratamiento considerado como "gold standard" en el tratamiento de la incontinencia urinaria post prostatectomía radical. La incontinencia de orina post prostatectomía radical es una complicación que se presenta en un 5-25% de los pacientes sometidos a este tratamiento. Esta complicación genera en los pacientes un deterioro importante en cuanto a su calidad de vida. Tratamientos conservadores y mínimamente invasivos han sido utilizados sin éxito, c...

  12. Reduced pain and inflammation in juvenile and adult rats fed a ketogenic diet.

    Directory of Open Access Journals (Sweden)

    David N Ruskin

    2009-12-01

    Full Text Available The ketogenic diet is a high-fat, low-carbohydrate regimen that forces ketone-based rather than glucose-based cellular metabolism. Clinically, maintenance on a ketogenic diet has been proven effective in treating pediatric epilepsy and type II diabetes, and recent basic research provides evidence that ketogenic strategies offer promise in reducing brain injury. Cellular mechanisms hypothesized to be mobilized by ketone metabolism and underlying the success of ketogenic diet therapy, such as reduced reactive oxygen species and increased central adenosine, suggest that the ketolytic metabolism induced by the diet could reduce pain and inflammation. To test the effects of a ketone-based metabolism on pain and inflammation directly, we fed juvenile and adult rats a control diet (standard rodent chow or ketogenic diet (79% fat ad libitum for 3-4 weeks. We then quantified hindpaw thermal nociception as a pain measure and complete Freund's adjuvant-induced local hindpaw swelling and plasma extravasation (fluid movement from the vasculature as inflammation measures. Independent of age, maintenance on a ketogenic diet reduced the peripheral inflammatory response significantly as measured by paw swelling and plasma extravasation. The ketogenic diet also induced significant thermal hypoalgesia independent of age, shown by increased hindpaw withdrawal latency in the hotplate nociception test. Anti-inflammatory and hypoalgesic diet effects were generally more robust in juveniles. The ketogenic diet elevated plasma ketones similarly in both age groups, but caused slowed body growth only in juveniles. These data suggest that applying a ketogenic diet or exploiting cellular mechanisms associated with ketone-based metabolism offers new therapeutic opportunities for controlling pain and peripheral inflammation, and that such a metabolic strategy may offer significant benefits for children and adults.

  13. Fluid-driven origami-inspired artificial muscles

    Science.gov (United States)

    Li, Shuguang; Vogt, Daniel M.; Rus, Daniela; Wood, Robert J.

    2017-12-01

    Artificial muscles hold promise for safe and powerful actuation for myriad common machines and robots. However, the design, fabrication, and implementation of artificial muscles are often limited by their material costs, operating principle, scalability, and single-degree-of-freedom contractile actuation motions. Here we propose an architecture for fluid-driven origami-inspired artificial muscles. This concept requires only a compressible skeleton, a flexible skin, and a fluid medium. A mechanical model is developed to explain the interaction of the three components. A fabrication method is introduced to rapidly manufacture low-cost artificial muscles using various materials and at multiple scales. The artificial muscles can be programed to achieve multiaxial motions including contraction, bending, and torsion. These motions can be aggregated into systems with multiple degrees of freedom, which are able to produce controllable motions at different rates. Our artificial muscles can be driven by fluids at negative pressures (relative to ambient). This feature makes actuation safer than most other fluidic artificial muscles that operate with positive pressures. Experiments reveal that these muscles can contract over 90% of their initial lengths, generate stresses of ˜600 kPa, and produce peak power densities over 2 kW/kg—all equal to, or in excess of, natural muscle. This architecture for artificial muscles opens the door to rapid design and low-cost fabrication of actuation systems for numerous applications at multiple scales, ranging from miniature medical devices to wearable robotic exoskeletons to large deployable structures for space exploration.

  14. Artificial Astrocytes Improve Neural Network Performance

    Science.gov (United States)

    Porto-Pazos, Ana B.; Veiguela, Noha; Mesejo, Pablo; Navarrete, Marta; Alvarellos, Alberto; Ibáñez, Oscar; Pazos, Alejandro; Araque, Alfonso

    2011-01-01

    Compelling evidence indicates the existence of bidirectional communication between astrocytes and neurons. Astrocytes, a type of glial cells classically considered to be passive supportive cells, have been recently demonstrated to be actively involved in the processing and regulation of synaptic information, suggesting that brain function arises from the activity of neuron-glia networks. However, the actual impact of astrocytes in neural network function is largely unknown and its application in artificial intelligence remains untested. We have investigated the consequences of including artificial astrocytes, which present the biologically defined properties involved in astrocyte-neuron communication, on artificial neural network performance. Using connectionist systems and evolutionary algorithms, we have compared the performance of artificial neural networks (NN) and artificial neuron-glia networks (NGN) to solve classification problems. We show that the degree of success of NGN is superior to NN. Analysis of performances of NN with different number of neurons or different architectures indicate that the effects of NGN cannot be accounted for an increased number of network elements, but rather they are specifically due to astrocytes. Furthermore, the relative efficacy of NGN vs. NN increases as the complexity of the network increases. These results indicate that artificial astrocytes improve neural network performance, and established the concept of Artificial Neuron-Glia Networks, which represents a novel concept in Artificial Intelligence with implications in computational science as well as in the understanding of brain function. PMID:21526157

  15. Artificial astrocytes improve neural network performance.

    Directory of Open Access Journals (Sweden)

    Ana B Porto-Pazos

    Full Text Available Compelling evidence indicates the existence of bidirectional communication between astrocytes and neurons. Astrocytes, a type of glial cells classically considered to be passive supportive cells, have been recently demonstrated to be actively involved in the processing and regulation of synaptic information, suggesting that brain function arises from the activity of neuron-glia networks. However, the actual impact of astrocytes in neural network function is largely unknown and its application in artificial intelligence remains untested. We have investigated the consequences of including artificial astrocytes, which present the biologically defined properties involved in astrocyte-neuron communication, on artificial neural network performance. Using connectionist systems and evolutionary algorithms, we have compared the performance of artificial neural networks (NN and artificial neuron-glia networks (NGN to solve classification problems. We show that the degree of success of NGN is superior to NN. Analysis of performances of NN with different number of neurons or different architectures indicate that the effects of NGN cannot be accounted for an increased number of network elements, but rather they are specifically due to astrocytes. Furthermore, the relative efficacy of NGN vs. NN increases as the complexity of the network increases. These results indicate that artificial astrocytes improve neural network performance, and established the concept of Artificial Neuron-Glia Networks, which represents a novel concept in Artificial Intelligence with implications in computational science as well as in the understanding of brain function.

  16. Artificial astrocytes improve neural network performance.

    Science.gov (United States)

    Porto-Pazos, Ana B; Veiguela, Noha; Mesejo, Pablo; Navarrete, Marta; Alvarellos, Alberto; Ibáñez, Oscar; Pazos, Alejandro; Araque, Alfonso

    2011-04-19

    Compelling evidence indicates the existence of bidirectional communication between astrocytes and neurons. Astrocytes, a type of glial cells classically considered to be passive supportive cells, have been recently demonstrated to be actively involved in the processing and regulation of synaptic information, suggesting that brain function arises from the activity of neuron-glia networks. However, the actual impact of astrocytes in neural network function is largely unknown and its application in artificial intelligence remains untested. We have investigated the consequences of including artificial astrocytes, which present the biologically defined properties involved in astrocyte-neuron communication, on artificial neural network performance. Using connectionist systems and evolutionary algorithms, we have compared the performance of artificial neural networks (NN) and artificial neuron-glia networks (NGN) to solve classification problems. We show that the degree of success of NGN is superior to NN. Analysis of performances of NN with different number of neurons or different architectures indicate that the effects of NGN cannot be accounted for an increased number of network elements, but rather they are specifically due to astrocytes. Furthermore, the relative efficacy of NGN vs. NN increases as the complexity of the network increases. These results indicate that artificial astrocytes improve neural network performance, and established the concept of Artificial Neuron-Glia Networks, which represents a novel concept in Artificial Intelligence with implications in computational science as well as in the understanding of brain function.

  17. Artificial organ engineering

    CERN Document Server

    Annesini, Maria Cristina; Piemonte, Vincenzo; Turchetti, Luca

    2017-01-01

    Artificial organs may be considered as small-scale process plants, in which heat, mass and momentum transfer operations and, possibly, chemical transformations are carried out. This book proposes a novel analysis of artificial organs based on the typical bottom-up approach used in process engineering. Starting from a description of the fundamental physico-chemical phenomena involved in the process, the whole system is rebuilt as an interconnected ensemble of elemental unit operations. Each artificial organ is presented with a short introduction provided by expert clinicians. Devices commonly used in clinical practice are reviewed and their performance is assessed and compared by using a mathematical model based approach. Whilst mathematical modelling is a fundamental tool for quantitative descriptions of clinical devices, models are kept simple to remain focused on the essential features of each process. Postgraduate students and researchers in the field of chemical and biomedical engineering will find that t...

  18. Evolution of an artificial neural network based autonomous land vehicle controller.

    Science.gov (United States)

    Baluja, S

    1996-01-01

    This paper presents an evolutionary method for creating an artificial neural network based autonomous land vehicle controller. The evolved controllers perform better in unseen situations than those trained with an error backpropagation learning algorithm designed for this task. In this paper, an overview of the previous connectionist based approaches to this task is given, and the evolutionary algorithms used in this study are described in detail. Methods for reducing the high computational costs of training artificial neural networks with evolutionary algorithms are explored. Error metrics specific to the task of autonomous vehicle control are introduced; the evolutionary algorithms guided by these error metrics reveal improved performance over those guided by the standard sum-squared error metric. Finally, techniques for integrating evolutionary search and error backpropagation are presented. The evolved networks are designed to control Carnegie Mellon University's NAVLAB vehicles in road following tasks.

  19. The biochemical changes in hippocampal formation occurring in normal and seizure experiencing rats as a result of a ketogenic diet.

    Science.gov (United States)

    Chwiej, Joanna; Skoczen, Agnieszka; Janeczko, Krzysztof; Kutorasinska, Justyna; Matusiak, Katarzyna; Figiel, Henryk; Dumas, Paul; Sandt, Christophe; Setkowicz, Zuzanna

    2015-04-07

    In this study, ketogenic diet-induced biochemical changes occurring in normal and epileptic hippocampal formations were compared. Four groups of rats were analyzed, namely seizure experiencing animals and normal rats previously fed with ketogenic (KSE and K groups respectively) or standard laboratory diet (NSE and N groups respectively). Synchrotron radiation based Fourier-transform infrared microspectroscopy was used for the analysis of distributions of the main organic components (proteins, lipids, compounds containing phosphate group(s)) and their structural modifications as well as anomalies in creatine accumulation with micrometer spatial resolution. Infrared spectra recorded in the molecular layers of the dentate gyrus (DG) areas of normal rats on a ketogenic diet (K) presented increased intensity of the 1740 cm(-1) absorption band. This originates from the stretching vibrations of carbonyl groups and probably reflects increased accumulation of ketone bodies occurring in animals on a high fat diet compared to those fed with a standard laboratory diet (N). The comparison of K and N groups showed, moreover, elevated ratios of absorbance at 1634 and 1658 cm(-1) for DG internal layers and increased accumulation of creatine deposits in sector 3 of the Ammon's horn (CA3) hippocampal area of ketogenic diet fed rats. In multiform and internal layers of CA3, seizure experiencing animals on ketogenic diet (KSE) presented a lower ratio of absorbance at 1634 and 1658 cm(-1) compared to rats on standard laboratory diet (NSE). Moreover, in some of the examined cellular layers, the increased intensity of the 2924 cm(-1) lipid band as well as the massifs of 2800-3000 cm(-1) and 1360-1480 cm(-1), was found in KSE compared to NSE animals. The intensity of the 1740 cm(-1) band was diminished in DG molecular layers of KSE rats. The ketogenic diet did not modify the seizure induced anomalies in the unsaturation level of lipids or the number of creatine deposits.

  20. Mouse Models of Diet-Induced Nonalcoholic Steatohepatitis Reproduce the Heterogeneity of the Human Disease

    Science.gov (United States)

    Machado, Mariana Verdelho; Michelotti, Gregory Alexander; Xie, Guanhua; de Almeida, Thiago Pereira; Boursier, Jerome; Bohnic, Brittany; Guy, Cynthia D.; Diehl, Anna Mae

    2015-01-01

    Background and aims Non-alcoholic steatohepatitis (NASH), the potentially progressive form of nonalcoholic fatty liver disease (NAFLD), is the pandemic liver disease of our time. Although there are several animal models of NASH, consensus regarding the optimal model is lacking. We aimed to compare features of NASH in the two most widely-used mouse models: methionine-choline deficient (MCD) diet and Western diet. Methods Mice were fed standard chow, MCD diet for 8 weeks, or Western diet (45% energy from fat, predominantly saturated fat, with 0.2% cholesterol, plus drinking water supplemented with fructose and glucose) for 16 weeks. Liver pathology and metabolic profile were compared. Results The metabolic profile associated with human NASH was better mimicked by Western diet. Although hepatic steatosis (i.e., triglyceride accumulation) was also more severe, liver non-esterified fatty acid content was lower than in the MCD diet group. NASH was also less severe and less reproducible in the Western diet model, as evidenced by less liver cell death/apoptosis, inflammation, ductular reaction, and fibrosis. Various mechanisms implicated in human NASH pathogenesis/progression were also less robust in the Western diet model, including oxidative stress, ER stress, autophagy deregulation, and hedgehog pathway activation. Conclusion Feeding mice a Western diet models metabolic perturbations that are common in humans with mild NASH, whereas administration of a MCD diet better models the pathobiological mechanisms that cause human NAFLD to progress to advanced NASH. PMID:26017539

  1. Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease.

    Directory of Open Access Journals (Sweden)

    Mariana Verdelho Machado

    Full Text Available Non-alcoholic steatohepatitis (NASH, the potentially progressive form of nonalcoholic fatty liver disease (NAFLD, is the pandemic liver disease of our time. Although there are several animal models of NASH, consensus regarding the optimal model is lacking. We aimed to compare features of NASH in the two most widely-used mouse models: methionine-choline deficient (MCD diet and Western diet.Mice were fed standard chow, MCD diet for 8 weeks, or Western diet (45% energy from fat, predominantly saturated fat, with 0.2% cholesterol, plus drinking water supplemented with fructose and glucose for 16 weeks. Liver pathology and metabolic profile were compared.The metabolic profile associated with human NASH was better mimicked by Western diet. Although hepatic steatosis (i.e., triglyceride accumulation was also more severe, liver non-esterified fatty acid content was lower than in the MCD diet group. NASH was also less severe and less reproducible in the Western diet model, as evidenced by less liver cell death/apoptosis, inflammation, ductular reaction, and fibrosis. Various mechanisms implicated in human NASH pathogenesis/progression were also less robust in the Western diet model, including oxidative stress, ER stress, autophagy deregulation, and hedgehog pathway activation.Feeding mice a Western diet models metabolic perturbations that are common in humans with mild NASH, whereas administration of a MCD diet better models the pathobiological mechanisms that cause human NAFLD to progress to advanced NASH.

  2. A Consensus Proposal for Nutritional Indicators to Assess the Sustainability of a Healthy Diet: The Mediterranean Diet as a Case Study.

    Science.gov (United States)

    Donini, Lorenzo M; Dernini, Sandro; Lairon, Denis; Serra-Majem, Lluis; Amiot, Marie-Josèphe; Del Balzo, Valeria; Giusti, Anna-Maria; Burlingame, Barbara; Belahsen, Rekia; Maiani, Giuseppe; Polito, Angela; Turrini, Aida; Intorre, Federica; Trichopoulou, Antonia; Berry, Elliot M

    2016-01-01

    There is increasing evidence of the multiple effects of diets on public health nutrition, society, and environment. Sustainability and food security are closely interrelated. The traditional Mediterranean Diet (MD) is recognized as a healthier dietary pattern with a lower environmental impact. As a case study, the MD may guide innovative inter-sectorial efforts to counteract the degradation of ecosystems, loss of biodiversity, and homogeneity of diets due to globalization through the improvement of sustainable healthy dietary patterns. This consensus position paper defines a suite of the most appropriate nutrition and health indicators for assessing the sustainability of diets based on the MD. In 2011, an informal International Working Group from different national and international institutions was convened. Through online and face-to-face brainstorming meetings over 4 years, a set of nutrition and health indicators for sustainability was identified and refined. Thirteen nutrition indicators of sustainability relating were identified in five areas. Biochemical characteristics of food (A1. Vegetable/animal protein consumption ratios; A2. Average dietary energy adequacy; A3. Dietary Energy Density Score; A4. Nutrient density of diet), Food Quality (A5. Fruit and vegetable consumption/intakes; A6. Dietary Diversity Score), Environment (A7. Food biodiversity composition and consumption; A8. Rate of Local/regional foods and seasonality; A9. Rate of eco-friendly food production and/or consumption), Lifestyle (A10. Physical activity/physical inactivity prevalence; A11. Adherence to the Mediterranean dietary pattern), Clinical Aspects (A12. Diet-related morbidity/mortality statistics; A13. Nutritional Anthropometry). A standardized set of information was provided for each indicator: definition, methodology, background, data sources, limitations of the indicator, and references. The selection and analysis of these indicators has been performed (where possible) with

  3. Artificial neural networks for spatial distribution of fuel assemblies in reload of PWR reactors

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Edyene; Castro, Victor F.; Velásquez, Carlos E.; Pereira, Claubia, E-mail: claubia@nuclear.ufmg.br [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Programa de Pós-Graduação em Ciências e Técnicas Nucleares

    2017-07-01

    An artificial neural network methodology is being developed in order to find an optimum spatial distribution of the fuel assemblies in a nuclear reactor core during reload. The main bounding parameter of the modelling was the neutron multiplication factor, k{sub ef{sub f}}. The characteristics of the network are defined by the nuclear parameters: cycle, burnup, enrichment, fuel type, and average power peak of each element. These parameters were obtained by the ORNL nuclear code package SCALE6.0. As for the artificial neural network, the ANN Feedforward Multi{sub L}ayer{sub P}erceptron with various layers and neurons were constructed. Three algorithms were used and tested: LM (Levenberg-Marquardt), SCG (Scaled Conjugate Gradient) and BayR (Bayesian Regularization). Artificial neural network have implemented using MATLAB 2015a version. As preliminary results, the spatial distribution of the fuel assemblies in the core using a neural network was slightly better than the standard core. (author)

  4. Artificial neural networks for spatial distribution of fuel assemblies in reload of PWR reactors

    International Nuclear Information System (INIS)

    Oliveira, Edyene; Castro, Victor F.; Velásquez, Carlos E.; Pereira, Claubia

    2017-01-01

    An artificial neural network methodology is being developed in order to find an optimum spatial distribution of the fuel assemblies in a nuclear reactor core during reload. The main bounding parameter of the modelling was the neutron multiplication factor, k ef f . The characteristics of the network are defined by the nuclear parameters: cycle, burnup, enrichment, fuel type, and average power peak of each element. These parameters were obtained by the ORNL nuclear code package SCALE6.0. As for the artificial neural network, the ANN Feedforward Multi L ayer P erceptron with various layers and neurons were constructed. Three algorithms were used and tested: LM (Levenberg-Marquardt), SCG (Scaled Conjugate Gradient) and BayR (Bayesian Regularization). Artificial neural network have implemented using MATLAB 2015a version. As preliminary results, the spatial distribution of the fuel assemblies in the core using a neural network was slightly better than the standard core. (author)

  5. Introduction to Artificial Neural Networks

    DEFF Research Database (Denmark)

    Larsen, Jan

    1999-01-01

    The note addresses introduction to signal analysis and classification based on artificial feed-forward neural networks.......The note addresses introduction to signal analysis and classification based on artificial feed-forward neural networks....

  6. RCT of a high-protein diet on hunger motivation and weight-loss in obese children: an extension and replication.

    Science.gov (United States)

    Duckworth, Lauren C; Gately, Paul J; Radley, Duncan; Cooke, Carlton B; King, Roderick F G J; Hill, Andrew J

    2009-09-01

    This study aimed to evaluate the weight loss and hunger motivation effects of an energy-restricted high-protein (HP) diet in overweight and obese children. In total, 95 overweight and obese children attended an 8-week (maximum) program of physical activity, reduced-energy intake, and behavior change education. Children were randomly assigned to one of two isoenergetic diets (standard (SP): 15% protein; HP: 25% protein), based on individually estimated energy requirements. Anthropometry and body composition were assessed at the start and end of the program and appetite and mood ratings completed on the first 3 consecutive weekdays of each week children attended camp. The HP diet had no greater effect on weight loss, body composition, or changes in appetite or mood when compared to the SP diet. Overall, campers lost 5.2 +/- 3.0 kg in body weight and reduced their BMI standard deviation score (sds) by 0.25. Ratings of desire to eat increased significantly over the duration of the intervention, irrespective of diet. This is the third time we have reported an increase in hunger motivation in weight-loss campers and replicates our previous failure to block this with a higher protein diet. Further work is warranted into the management of hunger motivation as a result of negative energy balance.

  7. Effect of feeding three lysine to energy diets on growth, body composition and age at puberty in replacement gilts

    Science.gov (United States)

    This study evaluated the effect of diets differing in standard ileal digestible (SID) lysine on lysine intake, growth rate, body composition and age at puberty on maternal line gilts. Crossbred Large White×Landrace gilts (n =641) were fed corn-soybean diets differing in SID lysine concentration (%, ...

  8. Mediterranean Diet: From a Healthy Diet to a Sustainable Dietary Pattern

    Science.gov (United States)

    Dernini, Sandro; Berry, Elliot M.

    2015-01-01

    The notion of the Mediterranean diet has undergone a progressive evolution over the past 60 years, from a healthy dietary pattern to a sustainable dietary pattern, in which nutrition, food, cultures, people, environment, and sustainability all interact into a new model of a sustainable diet. An overview of the historical antecedents and recent increased interest in the Mediterranean diet is presented and challenges related to how to improve the sustainability of the Mediterranean diet are identified. Despite its increasing popularity worldwide, adherence to the Mediterranean diet model is decreasing for multifactorial influences – life styles changes, food globalization, economic, and socio-cultural factors. These changes pose serious threats to the preservation and transmission of the Mediterranean diet heritage to present and future generations. Today’s challenge is to reverse such trends. A greater focus on the Mediterranean diet’s potential as a sustainable dietary pattern, instead than just on its well-documented healthy benefits, can contribute to its enhancement. More cross-disciplinary studies on environmental, economic and socio-cultural, and sustainability dimensions of the Mediterranean diet are foreseen as a critical need. PMID:26284249

  9. Vegetarian Diet

    Science.gov (United States)

    A vegetarian diet focuses on plants for food. These include fruits, vegetables, dried beans and peas, grains, seeds and nuts. There is no single type of vegetarian diet. Instead, vegetarian eating patterns usually fall into the ...

  10. Diets: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish Mediterranean diet (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Diets updates by ... foods Diet-busting foods Mediterranean diet Related Health Topics Child Nutrition DASH Eating Plan Diabetic Diet Nutrition ...

  11. Influence of diet with kale on lipid peroxides and malondialdehyde levels in blood serum of laboratory rats over intoxication with paraquat.

    Science.gov (United States)

    Sikora, Elżbieta; Bodziarczyk, Izabela

    2013-01-01

    Organism's lipid peroxidation is one of the most often examined and known physiological process evoked by free radicals. It concerns oxidation reaction of unsaturated fatty acid and/or other lipids leading to lipid oxidation products (LOP), which as a result of further changes generate among others the malondialdehyde molecules. The aim of the work was an estimation if raw or cooked kale addition to rat's diet influences antioxidant defense efficiency in their organisms in comparison to rats fed with standard AIN-93G diet. The experiment was conducted with 36 Wistar strain, male rats over 21 days. The rats were divided into 3 groups (each 12 stuck) which were fed with: standard diet AIN-93G (2 groups), AIN-93G diet with 10% addition of raw kale (2 groups), and AIN-93G with 10% addition of cooked lyophilised kale. The total content of polyphenols (FC method) and antioxidant activity (ABTS+•) were previously determined in raw and then in cooked kale. On the 20th day of experiment, half of rats (6 stuck) of each kind of the diet were injected intraperitoneally by the solution of paraquat (PQ) in physiological salt to evoke the oxidative stress. The next day animals were stunned and blood from their hearts was sampled. In the obtained serum, the levels of lipid oxidation products (LOP) and malondialdehyde (MDA) were assessed. It was observed that in blood serum of rats fed with modified diet with raw and cooked lyophilised kale addition the lipid oxides level was lower in comparison to control group fed with standard diet (p kale addition. Diet with kale, both raw and cooked, efficiently inhibited the lipid peroxidation process in rats' organisms, ongoing during natural metabolism and during evoked oxidative stress.

  12. How to teach artificial organs.

    Science.gov (United States)

    Zapanta, Conrad M; Borovetz, Harvey S; Lysaght, Michael J; Manning, Keefe B

    2011-01-01

    Artificial organs education is often an overlooked field for many bioengineering and biomedical engineering students. The purpose of this article is to describe three different approaches to teaching artificial organs. This article can serve as a reference for those who wish to offer a similar course at their own institutions or incorporate these ideas into existing courses. Artificial organ classes typically fulfill several ABET (Accreditation Board for Engineering and Technology) criteria, including those specific to bioengineering and biomedical engineering programs.

  13. Artificial Neural Network Analysis System

    Science.gov (United States)

    2001-02-27

    Contract No. DASG60-00-M-0201 Purchase request no.: Foot in the Door-01 Title Name: Artificial Neural Network Analysis System Company: Atlantic... Artificial Neural Network Analysis System 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Powell, Bruce C 5d. PROJECT NUMBER 5e. TASK NUMBER...34) 27-02-2001 Report Type N/A Dates Covered (from... to) ("DD MON YYYY") 28-10-2000 27-02-2001 Title and Subtitle Artificial Neural Network Analysis

  14. Over the counter (OTC) artificial tear drops for dry eye syndrome.

    Science.gov (United States)

    Pucker, Andrew D; Ng, Sueko M; Nichols, Jason J

    2016-02-23

    another type of dry-eye therapy. We followed the standard methodological procedures expected by Cochrane. Two authors independently screened the search results, reviewed full-text copies for eligibility, examined risk of bias, and extracted data. We performed meta-analysis for trials that compared similar interventions and reported comparable outcomes with sufficient data. We summarized all other included trial results in the text. We included 43 randomized controlled trials (3497 participants with dry eye). Due to the heterogeneity of study characteristics among the included trials with respect to types of diagnostic criteria, interventions, comparisons, and measurements taken, our ability to perform meta-analyses was limited. The review found that, in general, there was uncertainty whether different OTC artificial tears provide similar relief of signs and symptoms when compared with each other or placebo. Nevertheless, we found that 0.2% polyacrylic acid-based artificial tears were consistently more effective at treating dry eye symptoms than 1.4% polyvinyl alcohol-based artificial tears in two trials assessing this comparison (175 participants). All other included artificial tears produced contradictory between-group results or found no between-group differences. Our review also found that OTC artificial tears may be generally safe, but not without adverse events. Overall, we assessed the quality of evidence as low due to high risks of bias among included trials and poor reporting of outcome measures which were insufficient for quantitative analysis. Furthermore, we identified an additional 18 potentially eligible trials that were reported only in clinical trial registers with no associated results or publications. These trials reportedly enrolled 2079 total participants for whom no data are available. Such lack of reporting of trial results represents a high risk of publication bias. OTC artificial tears may be safe and effective means for treating dry eye syndrome

  15. Encouraging effects of a short-term, adapted Nordic diet intervention on skin microvascular function and skin oxygen tension in younger and older adults.

    Science.gov (United States)

    Rogerson, David; McNeill, Scott; Könönen, Heidi; Klonizakis, Markos

    2018-05-01

    The microvascular benefits of regional diets appear in the literature; however, little is known about Nordic-type diets. We investigated the effects of a short-term, adapted, Nordic diet on microvascular function in younger and older individuals at rest and during activity. Thirteen young (mean age: 28 y; standard deviation: 5 y) and 15 older (mean age: 68 y; standard deviation: 6 y) participants consumed a modified Nordic diet for 4 wk. Laser Doppler flowmetry and transcutaneous oxygen monitoring were used to assess cutaneous microvascular function and oxygen tension pre- and postintervention; blood pressure, body mass, body fat percentage, ratings of perceived exertion, and peak heart rate during activity were examined concurrently. Axon-mediated vasodilation improved in older participants (1.17 [0.30] to 1.30 [0.30]; P Nordic diet might improve microvascular health. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Artificial Psychology: The Psychology of AI

    Directory of Open Access Journals (Sweden)

    James A. Crowder

    2013-12-01

    Full Text Available Having artificially intelligent machines that think, learn, reason, experience, and can function autonomously, without supervision, is one of the most intriguing goals in all of Computer Science. As the types of problems we would like machines to solve get more complex, it is becoming a necessary goal as well. One of the many problems associated with this goal is that what learning and reasoning are have so many possible meanings that the solution can easily get lost in the sea of opinions and options. The goal of this paper is to establish some foundational principles, theory, and concepts that we feel are the backbone of real, autonomous Artificial Intelligence. With this fully autonomous, learning, reasoning, artificially intelligent system (an artificial brain, comes the need to possess constructs in its hardware and software that mimic processes and subsystems that exist within the human brain, including intuitive and emotional memory concepts. Presented here is a discussion of the psychological constructs of artificial intelligence and how they might play out in an artificial mind.

  17. Artificial Intelligence in Civil Engineering

    Directory of Open Access Journals (Sweden)

    Pengzhen Lu

    2012-01-01

    Full Text Available Artificial intelligence is a branch of computer science, involved in the research, design, and application of intelligent computer. Traditional methods for modeling and optimizing complex structure systems require huge amounts of computing resources, and artificial-intelligence-based solutions can often provide valuable alternatives for efficiently solving problems in the civil engineering. This paper summarizes recently developed methods and theories in the developing direction for applications of artificial intelligence in civil engineering, including evolutionary computation, neural networks, fuzzy systems, expert system, reasoning, classification, and learning, as well as others like chaos theory, cuckoo search, firefly algorithm, knowledge-based engineering, and simulated annealing. The main research trends are also pointed out in the end. The paper provides an overview of the advances of artificial intelligence applied in civil engineering.

  18. Knowledge-Based Aircraft Automation: Managers Guide on the use of Artificial Intelligence for Aircraft Automation and Verification and Validation Approach for a Neural-Based Flight Controller

    Science.gov (United States)

    Broderick, Ron

    1997-01-01

    The ultimate goal of this report was to integrate the powerful tools of artificial intelligence into the traditional process of software development. To maintain the US aerospace competitive advantage, traditional aerospace and software engineers need to more easily incorporate the technology of artificial intelligence into the advanced aerospace systems being designed today. The future goal was to transition artificial intelligence from an emerging technology to a standard technology that is considered early in the life cycle process to develop state-of-the-art aircraft automation systems. This report addressed the future goal in two ways. First, it provided a matrix that identified typical aircraft automation applications conducive to various artificial intelligence methods. The purpose of this matrix was to provide top-level guidance to managers contemplating the possible use of artificial intelligence in the development of aircraft automation. Second, the report provided a methodology to formally evaluate neural networks as part of the traditional process of software development. The matrix was developed by organizing the discipline of artificial intelligence into the following six methods: logical, object representation-based, distributed, uncertainty management, temporal and neurocomputing. Next, a study of existing aircraft automation applications that have been conducive to artificial intelligence implementation resulted in the following five categories: pilot-vehicle interface, system status and diagnosis, situation assessment, automatic flight planning, and aircraft flight control. The resulting matrix provided management guidance to understand artificial intelligence as it applied to aircraft automation. The approach taken to develop a methodology to formally evaluate neural networks as part of the software engineering life cycle was to start with the existing software quality assurance standards and to change these standards to include neural network

  19. Mediterranean diet and life expectancy; beyond olive oil, fruits and vegetables

    Science.gov (United States)

    Martinez-Gonzalez, Miguel A.; Martín-Calvo, Nerea

    2018-01-01

    Purpose to review the recent relevant evidence of the effects of the Mediterranean diet and lifestyle on health (2015 and first months of 2016). Recent findings Large observational prospective epidemiological studies with adequate control of confounding and two large randomized trials support the benefits of the Mediterranean dietary pattern to increase life expectancy, reduce the risk of major chronic disease, and improve quality of life and well-being. Recently, 19 new reports from large prospective studies showed –with nearly perfect consistency– strong benefits of the Mediterranean diet to reduce the risk of myocardial infarction, stroke, total mortality, heart failure and disability. Interestingly, two large and well-conducted cohorts reported significant cardiovascular benefits after using repeated measurements of diet during a long follow-up period. Besides, PREDIMED, the largest randomized trial with Mediterranean diet, recently reported benefits of this dietary pattern to prevent cognitive decline and breast cancer. Summary In the era of evidence-based medicine, the Mediterranean diet represents the gold standard in preventive medicine, probably due to the harmonic combination of many elements with antioxidant and antiinflammatory properties, which overwhelm any single nutrient or food item. The whole seems more important than the sum of its parts. PMID:27552476

  20. Progress on the artificial rearing of Anastrepha fraterculus (Wied.) (Diptera: Tephritidae) in Colombia

    International Nuclear Information System (INIS)

    Nunez Bueno, L.; Guzman Duenas, R.

    1999-01-01

    With the purpose of evaluating post-harvest quarantine treatments for fruits in Colombia, we have established experimental colonies of fruit flies (Diptera: Tephritidae) at the Colombian Agricultural Institute (ICA), plant quarantine Laboratory Ibague (Tol.) at 24 deg. C, 70-80% RH, and 10 hr light. The procedures and results refer only to A. fraterculus from September 1994 to September 1996. The first adults, obtained from Coffea arabica L. cherries, were initially multiplied in fruits and later put on artificial diet. The handling procedures, diets and data collected are adapted from those established by USDA-ARA 1981, Celedonio et al. 1989, Gonzalez et al. Martinez et al. 1987, and others, that were used for Anastrepha spp. The average percentages of recuperation between stages that were hatched 66.0±1.0; first to third instar larvae 28.12±14.4; third instar larvae to pupae 81.80±3.0; pupae to adult 75.82±3.4. Additional data related to partial mortality of the stages are also discussed. The average recuperation from eggs to third instar larvae of 17.57%, and from eggs to emerged adults of 9.5±4.9, is low and indicates the necessity of doing basic research to improve the procedures. (author)