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Sample records for standalone cage assisted

  1. Subsidence after single-level anterior cervical fusion with a stand-alone cage.

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    Park, Jae-Young; Choi, Ki-Young; Moon, Bong Ju; Hur, Hyuk; Jang, Jae-Won; Lee, Jung-Kil

    2016-11-01

    To investigate the risk factors for subsidence in patients treated with stand-alone anterior cervical discectomy and fusion (ACDF) using polyetheretherketone (PEEK) cages for single-level degenerative cervical disease. Seventy-seven consecutive patients who underwent single-level stand-alone ACDF with a PEEK cage between 2005 and 2012 were included. Subsidence was defined as a decrease in the interbody height of more than 3mm on radiographs at the 1-year follow-up compared with that in the immediate post-operative image. Patients were divided into the subsidence and non-subsidence groups. The following factors were investigated in relation to the occurrence of subsidence: age, pre-operative overall cervical sagittal angle, segmental angle of the operated level, interbody height, cage height, cage devices and cage location (distance between anterior margin of the body endplate and that of the cage). The clinical outcomes were assessed with visual analog scale, modified Japanese Orthopedic Association score and neck disability index. Twenty-six out of the 77 (33.8%) patients had radiological signs of cage subsidence. Solid fusion was achieved in 25 out of the 26 patients (96.2%) in the subsidence group and in 47 out of the 51 patients (92.2%) in the non-subsidence group. More than 3mm distance between anterior margin of the vertebral body and that of the cage was significantly associated with subsidence (psubsidence did not correlate with fusion rate or clinical outcomes. Cage location was the only significant risk factor. Therefore, cage location should be taken into consideration during stand-alone ACDF using PEEK cages. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Outcomes of contemporary use of rectangular titanium stand-alone cages in anterior cervical discectomy and fusion: cage subsidence and cervical alignment.

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    Yamagata, Toru; Takami, Toshihiro; Uda, Takehiro; Ikeda, Hidetoshi; Nagata, Takashi; Sakamoto, Shinichi; Tsuyuguchi, Naohiro; Ohata, Kenji

    2012-12-01

    Cervical intervertebral disc replacement using a rectangular titanium stand-alone cage has become a standard procedure for anterior cervical discectomy and fusion (ACDF). We examined outcomes resulting from the contemporary use of rectangular titanium stand-alone cages for ACDF, particularly focusing on cage subsidence and subsequent kyphotic malalignment. Patient data were collected prospectively, and a total of 47 consecutive patients who underwent periodic follow-up of at least 1 year's duration after ACDF were studied retrospectively. Sixty-three rectangular titanium cages were implanted during 31 1-level and 16 2-level procedures. None of the patients developed surgery-related complications (including cage displacement or extrusion). Mean Neurosurgical Cervical Spine Scale scores were significantly improved at 1 year after surgery. Twelve of the 63 inserted cages (19.0%) were found to have cage subsidence, occurring in 11 of 47 patients (23.4%). There was no significant difference in functional recovery between patients with and without cage subsidence. Logistic regression analysis indicated that fusion level, cage size and cage position were significantly related to cage subsidence. The distraction ratio among patients with cage subsidence was significantly higher than that among patients without cage subsidence. Cage subsidence resulted in early deterioration of local angle and total alignment of the cervical spine. Although a longer follow-up is warranted, a good surgical outcome with negligible complications appears to justify the use of rectangular titanium stand-alone cages in 1- and 2-level ACDF. Excessive distraction at the fusion level should be avoided, and cage position should be adjusted to the anterior vertical line. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Radiographic and clinical evaluation of cage subsidence after stand-alone lateral interbody fusion.

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    Marchi, Luis; Abdala, Nitamar; Oliveira, Leonardo; Amaral, Rodrigo; Coutinho, Etevaldo; Pimenta, Luiz

    2013-07-01

    Indirect decompression of the neural structures through interbody distraction and fusion in the lumbar spine is feasible, but cage subsidence may limit maintenance of the initial decompression. The influence of interbody cage size on subsidence and symptoms in minimally invasive lateral interbody fusion is heretofore unreported. The authors report the rate of cage subsidence after lateral interbody fusion, examine the clinical effects, and present a subsidence classification scale. The study was performed as an institutional review board-approved prospective, nonrandomized, comparative, single-center radiographic and clinical evaluation. Stand-alone short-segment (1- or 2-level) lateral lumbar interbody fusion was investigated with 12 months of postoperative follow-up. Two groups were compared. Forty-six patients underwent treatment at 61 lumbar levels with standard interbody cages (18 mm anterior/posterior dimension), and 28 patients underwent treatment at 37 lumbar levels with wide cages (22 mm). Standing lateral radiographs were used to measure segmental lumbar lordosis, disc height, and rate of subsidence. Subsidence was classified using the following scale: Grade 0, 0%-24% loss of postoperative disc height; Grade I, 25%-49%; Grade II, 50%-74%; and Grade III, 75%-100%. Fusion status was assessed on CT scanning, and pain and disability were assessed using the visual analog scale and Oswestry Disability Index. Complications and reoperations were recorded. Pain and disability improved similarly in both groups. While significant gains in segmental lumbar lordosis and disc height were observed overall, the standard group experienced less improvement due to the higher rate of interbody graft subsidence. A difference in the rate of subsidence between the groups was evident at 6 weeks (p = 0.027), 3 months (p = 0.042), and 12 months (p = 0.047). At 12 months, 70% in the standard group and 89% in the wide group had Grade 0 or I subsidence, and 30% in the standard group

  4. Subsidence and nonunion after anterior cervical interbody fusion using a stand-alone polyetheretherketone (PEEK) cage.

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    Yang, Jae Jun; Yu, Chang Hun; Chang, Bong-Soon; Yeom, Jin Sup; Lee, Jae Hyup; Lee, Choon-Ki

    2011-03-01

    The purposes of the present study are to evaluate the subsidence and nonunion that occurred after anterior cervical discectomy and fusion using a stand-alone intervertebral cage and to analyze the risk factors for the complications. Thirty-eight patients (47 segments) who underwent anterior cervical fusion using a stand-alone polyetheretherketone (PEEK) cage and an autologous cancellous iliac bone graft from June 2003 to August 2008 were enrolled in this study. The anterior and posterior segmental heights and the distance from the anterior edge of the upper vertebra to the anterior margin of the cage were measured on the plain radiographs. Subsidence was defined as ≥ a 2 mm (minor) or 3 mm (major) decrease of the segmental height at the final follow-up compared to that measured at the immediate postoperative period. Nonunion was evaluated according to the instability being ≥ 2 mm in the interspinous distance on the flexion-extension lateral radiographs. The anterior and posterior segmental heights decreased from the immediate postoperative period to the final follow-up at 1.33 ± 1.46 mm and 0.81 ± 1.27 mm, respectively. Subsidence ≥ 2 mm and 3 mm were observed in 12 segments (25.5%) and 7 segments (14.9%), respectively. Among the expected risk factors for subsidence, a smaller anteroposterior (AP) diameter (14 mm vs. 12 mm) of cages (p = 0.034; odds ratio [OR], 0.017) and larger intraoperative distraction (p = 0.041; OR, 3.988) had a significantly higher risk of subsidence. Intervertebral nonunion was observed in 7 segments (7/47, 14.9%). Compared with the union group, the nonunion group had a significantly higher ratio of two-level fusion to one-level fusions (p = 0.001). Anterior cervical fusion using a stand-alone cage with a large AP diameter while preventing anterior intraoperative over-distraction will be helpful to prevent the subsidence of cages. Two-level cervical fusion might require more careful attention for avoiding nonunion.

  5. Segmental kyphosis after cervical interbody fusion with stand-alone polyetheretherketone (PEEK) cages: a comparative study on 2 different PEEK cages.

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    Kim, Chi Heon; Chung, Chun Kee; Jahng, Tae-Ahn; Park, Sung Bae; Sohn, Seil; Lee, Sungjoon

    2015-02-01

    Retrospective comparative study. Two polyetheretherketone (PEEK) cages of different designs were compared in terms of the postoperative segmental kyphosis after anterior cervical discectomy and fusion. Segmental kyphosis occasionally occurs after the use of a stand-alone cage for anterior cervical discectomy and fusion. Although PEEK material seems to have less risk of segmental kyphosis compared with other materials, the occurrence of segmental kyphosis for PEEK cages has been reported to be from 0% to 29%. There have been a few reports that addressed the issue of PEEK cage design. A total of 41 consecutive patients who underwent single-level anterior discectomy and fusion with a stand-alone cage were included. Either a round tube-type (Solis; 18 patients, S-group) or a trapezoidal tube-type (MC+; 23 patients, M-group) cage was used. The contact area between the cage and the vertebral body is larger in MC+ than in Solis, and anchoring pins were present in the Solis cage. The effect of the cage type on the segmental angle (SA) (lordosis vs. kyphosis) at postoperative month 24 was analyzed. Preoperatively, segmental lordosis was present in 12/18 S-group and 16/23 M-group patients (P=0.84). The SA was more lordotic than the preoperative angle in both groups just after surgery, with no difference between groups (P=0.39). At 24 months, segmental lordosis was observed in 9/18 S-group and 20/23 M-group patients (P=0.01). The patients in M-group were 7.83 times more likely than patients in S-group (P=0.04; odds ratio, 7.83; 95% confidence interval, 1.09-56.28) not to develop segmental kyphosis. The design of the PEEK cage used may influence the SA, and this association needs to be considered when using stand-alone PEEK cages.

  6. Radiologic Assessment of Subsidence in Stand-Alone Cervical Polyetheretherketone (PEEK) Cage.

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    Ha, Sung-Kon; Park, Jung-Yul; Kim, Se-Hoon; Lim, Dong-Jun; Kim, Sang-Dae; Lee, Sang-Kook

    2008-12-01

    Aim of study was to find a proper method for assessing subsidence using a radiologic measurement following anterior cervical discectomy and fusion (ACDF) with stand-alone polyetheretherketone (PEEK), Solistrade mark cage. Forty-two patients who underwent ACDF with Solistrade mark cage were selected. With a minimum follow-up of 6 months, the retrospective investigation was conducted for 37 levels in 32 patients. Mean follow-up period was 18.9 months. Total intervertebral height (TIH) of two fused vertebral bodies was measured on digital radiographs with built-in software. Degree of subsidence (DeltaTIH) was reflected by the difference between the immediate postoperative and follow-up TIH. Change of postoperative disc space height (CT-MRDeltaTIH) was reflected by the difference between TIH of the preoperative mid-sagittal 2D CT and that of the preoperative mid-sagittal T1-weighted MRI. Compared to preoperative findings, postoperative disc height was increased in all cases and subsidence was observed only in 3 cases. For comparison of subsidence and non-subsidence group, TIH and CT-MRDeltaTIH of each group were analyzed. There was no statistically significant difference in TIH and CT-MRDeltaTIH between each group at 4 and 8 weeks, but a difference was observed at the last follow-up TIH (p=0.0497). ACDF with Solistrade mark cage was associated with relatively good radiologic long-term results. Fusion was achieved in 94.5% and subsidence occurred in 8.1% by the radiologic assessment. Statistical analysis reveals that the subsidence seen later than 8 weeks after surgery and the development of subsidence does not correlate statistically with the change of the postoperative disc space height.

  7. Use of stand-alone anchored intervertebral cage in the surgical treatment of patients with symptomatic cervical spondylosis

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    Tilen Žele

    2015-03-01

    Full Text Available Background:One of the most common surgical operations for treatment of cervical spondylosis is anterior cervical discectomy with fusion (ACDF. In order to achieve stable fusion after discectomy and avoid dysphagia the artificial stand-alone zero-profile cages with integrated screws were developed and introduced into clinical practice. Outcome and complications after ACDF with such cages were not adequately assessed yet.Methods:We analyzed 20 consecutive patients with cervical spondylosis treated in our institution with ACDF with stand-alone zero-profile cage Zero-P. Before and after surgery and then 6, 12 and 24 months after surgery we assessed the level of pain with VAS scale, severity of myelopathy with mJOA scale and dysphagia with four level scale. Treatment outcome was assessed after 2 years according to Odom's criteria.Results:No complications occurred during surgery or recovery after surgery. The VAS score after surgery and then after 6, 12 and 24 months was statistically significantly lower than before surgery (p<0.05. The mJOA scores were 6, 12 and 24 months after surgery statistically significantly higher than before surgery (p<0.05. Transient and mild dysphagia was present after surgery in 15% (3/20 of patients and 6, 12 or 24 months after surgery in none. Outcome after 2 years was excellent in 9 patients and good in 11 patients.Conclusions:Operative treatment of symptomatic cervical spondylosis with ACDF using stand-alone zero-profile cage with integrated screws is safe and efficient. Incidence of dysphagia after surgery is low and generally transient.

  8. Clinical and radiological outcome after anterior cervical discectomy and fusion with stand-alone empty polyetheretherketone (PEEK) cages.

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    Shiban, Ehab; Gapon, Karina; Wostrack, Maria; Meyer, Bernhard; Lehmberg, Jens

    2016-02-01

    To evaluate long-term results after one-, two-, and three-level anterior cervical discectomy and fusion (ACDF) with stand-alone empty polyetheretherketone (PEEK) cages. We performed a retrospective review of a consecutive patient cohort that underwent ACDF with stand-alone empty PEEK cages between 2007 and 2010 with a minimum follow-up of 12 months. Radiographic follow-up included static and flexion/extension radiographs. Changes in the operated segments were measured and compared to radiographs directly after surgery. Clinical outcome was evaluated by a physical examination, pain visual analog scale (VAS), and health-related quality of life (HRQL) using the EuroQOL questionnaire (EQ-5D). Analysis of associations between fusion, subsidence, cervical alignment, and clinical outcome parameters were performed. Of 407 consecutive cases, 318 met all inclusion criteria. Follow-up data were obtained from 265 (83 %) cases. The mean age at presentation was 55 years and 139 patients were male (52 %). In the sample, 127, 125, and 13 patients had one-, two-, and three-level surgeries, respectively; 132 (49 %) presented with spondylotic cervical myelopathy and 133 (50 %) with cervical radiculopathy. Fusion was achieved in 85, 95, and 94 % of segments in one-, two-, and three-level surgeries, respectively. Non-fusion was associated with higher VAS pain levels. Radiographic adjacent segment disease (ASD) was observed in 20, 29, and 15 % in one-, two-, and three-level surgeries, respectively. ASD was associated with lower HRQL. Subsidence was observed in 25, 27, and 15 % of segments in one-, two-, and three-level surgeries, respectively. However, this had no influence on clinical outcome. Follow-up operations for symptomatic adjacent disc disease and implant failure at index level were needed in 16 (6 %) and four (1.5 %) cases, respectively. Younger age was associated with better clinical outcome. Multilevel surgery favored better myelopathy outcomes and fusion reduced overall

  9. Anterior cervical discectomy and fusion using a stand-alone polyetheretherketone cage packed with local autobone : assessment of bone fusion and subsidence.

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    Park, Jeong-Ill; Cho, Dae-Chul; Kim, Kyoung-Tae; Sung, Joo-Kyung

    2013-09-01

    It remains debatable whether cervical spine fusion cages should be filled with any kind of bone or bone substitute. Cortical and subcortical bone from the anterior and posterior osteophytes of the segment could be used to fill the cage. The purposes of the present study are to evaluate the clinical outcomes and radiological outcomes including bone fusion and subsidence that occurred after anterior cervical discectomy and fusion using a stand-alone cage packed with local autobone graft. Thirty-one patients who underwent anterior cervical fusion using a stand-alone polyetheretherketone (PEEK) cage packed with local autobone graft from July 2009 to december 2011 were enrolled in this study. Bone fusion was assessed by cervical plain radiographs and computed tomographic scan. Nonunion was evaluated according to the absence of bony bridge on computed tomographic scan. Subsidence was defined as a ≥2 mm decrease of the interbody height at the final follow-up compared to that measured at the immediate postoperative period. Subsidence was observed in 7 patients (22.6%). Of 7 patients with subsidence greater 2 mm, nonunion was developed in 3. Three patients with subsidence greater 2 mm were related with endplate damage during intraoperative endplate preparation. Solid bone fusion was achieved in 28 out of 31 patients (90.3%). With proper patient selection and careful endplate preparation, anterior cervical discectomy and fusion (ACDF) using a stand-alone PEEK cage packed with local autobone graft could be a good alternative to the standard ACDF techniques with plating.

  10. Risk factors for subsidence in anterior cervical fusion with stand-alone polyetheretherketone (PEEK) cages: a review of 82 cases and 182 levels.

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    Kao, Ting-Hsien; Wu, Chen-Hao; Chou, Yu-Ching; Chen, Hsien-Te; Chen, Wen-Hsien; Tsou, Hsi-Kai

    2014-10-01

    To determine risk factors for subsidence in patients treated with anterior cervical discectomy and fusion (ACDF) and stand-alone polyetheretherketone (PEEK) cages. Records of patients with degenerative spondylosis or traumatic disc herniation resulting in radiculopathy or myelopathy between C2 and C7 who underwent ACDF with stand-alone PEEK cages were retrospectively reviewed. Cages were filled with autogenous cancellous bone harvested from iliac crest or hydroxyapatite. Subsidence was defined as a decrease of 3 mm or more of anterior or posterior disc height from that measured on the postoperative radiograph. Eighty-two patients (32 males, 50 females; 182 treatment levels) were included in the analysis. Most patients had 1-2 treatment levels (62.2 %), and 37.8 % had 3-4 treatment levels. Treatment levels were from C2-7. Of the 82 patients, cage subsidence occurred in 31 patients, and at 39 treatment levels. Multivariable analysis showed that subsidence was more likely to occur in patients with more than two treatment levels, and more likely to occur at treatment levels C5-7 than at levels C2-5. Subsidence was not associated with postoperative alignment change but associated with more disc height change (relatively oversized cage). Subsidence is associated with a greater number of treatment levels, treatment at C5-7 and relatively oversized cage use.

  11. [Biomechanicsl evaluation of a stand-alone interbody fusion cage based on porous TiO2/glass-ceramic on the human cervical spine].

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    Korinth, M C; Moersch, S; Ragoss, C; Schopphoff, E

    2003-12-01

    Recently, there has been a rapid increase in the use of cervical spine interbody fusion cages, differing in design and biomaterial used, in competition to autologous iliac bone graft and bone cement (PMMA). Limited biomechanical differences in primary stability, as well as advantages and disadvantages of each cage or material have been investigated in studies, using an in vitro human cervical spine model. 20 human cervical spine specimens were tested after fusion with either a cubical stand-alone interbody fusion cage manufactured from a new porous TiO2/glass composite (Ecopore) or PMMA after discectomy. Non-destructive biomechanical testing was performed, including flexion/extension and lateral bending using a spine testing apparatus. Three-dimensional segmental range of motion (ROM) was evaluated using an ultrasound measurement system. ROM increased more in flexion/extension and lateral bending after PMMA fusion (26.5%/36.1%), then after implantation of the Ecopore-cage (8.1%/7.8%). In this first biomechanical in vitro examination of a new porous ceramic bone replacement material a) the feasibility and reproducibility of biomechanical cadaveric cervical examination and its applicability was demonstrated, b) the stability of the ceramic cage as a stand alone interbody cage was confirmed in vitro, and c) basic information and knowledge for our intended biomechanical and histological in vivo testing, after implantation of Ecopore in cervical sheep spines, were obtained.

  12. Cage subsidence does not, but cervical lordosis improvement does affect the long-term results of anterior cervical fusion with stand-alone cage for degenerative cervical disc disease: a retrospective study.

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    Wu, Wen-Jian; Jiang, Lei-Sheng; Liang, Yu; Dai, Li-Yang

    2012-07-01

    Clinical outcomes of the stand-alone cage have been encouraging when used in anterior cervical discectomy and fusion (ACDF), but concerns remain regarding its complications, especially cage subsidence. This retrospective study was undertaken to investigate the long-term radiological and clinical outcomes of the stand-alone titanium cage and to evaluate the incidence of cage subsidence in relation to the clinical outcome in the surgical treatment of degenerative cervical disc disease. A total of 57 consecutive patients (68 levels) who underwent ACDF using a titanium box cage for the treatment of cervical radiculopathy and/or myelopathy were reviewed for the radiological and clinical outcomes. They were followed for at least 5 years. Radiographs were obtained before and after surgery, 3 months postoperatively, and at the final follow-up to determine the presence of fusion and cage subsidence. The Cobb angle of C2-C7 and the vertebral bodies adjacent to the treated disc were measured to evaluate the cervical sagittal alignment and local lordosis. The disc height was measured as well. The clinical outcomes were evaluated using the Japanese Orthopaedic Association (JOA) score for cervical myelopathy, before and after surgery, and at the final follow-up. The recovery rate of JOA score was also calculated. The Visual Analogue Scale (VAS) score of neck and radicular pain were evaluated as well. The fusion rate was 95.6% (65/68) 3 months after surgery. Successful bone fusion was achieved in all patients at the final follow-up. Cage subsidence occurred in 13 cages (19.1%) at 3-month follow-up; however, there was no relation between fusion and cage subsidence. Cervical and local lordosis improved after surgery, with the improvement preserved at the final follow-up. The preoperative disc height of both subsidence and non-subsidence patients was similar; however, postoperative posterior disc height (PDH) of subsidence group was significantly greater than of non-subsidence group

  13. Single anterior cervical discectomy and fusion (ACDF) using self- locking stand-alone polyetheretherketone (PEEK) cage: evaluation of pain and health-related quality of life.

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    Kapetanakis, Stylianos; Thomaidis, Tryfon; Charitoudis, George; Pavlidis, Pavlos; Theodosiadis, Panagiotis; Gkasdaris, Grigorios

    2017-09-01

    Anterior cervical discectomy and fusion (ACDF) constitutes the conventional treatment of cervical disc herniation due to degenerative disc disease (DDD). ACDF with plating presents a variety of complications postoperatively and stand-alone cages are thought to be a promising alternative. The aim of this study was firstly, to analyze prospectively collected data from a sample of patients treated with single ACDF using C-Plus self-locking stand-alone PEEK cage system, without the use of plates or screws, in order to evaluate pain levels of patients, utilizing Neck and Arm Pain scale as an expression of visual analogue scale (VAS). Secondly, we aimed to evaluate health-related quality of life, via the short-form 36 (SF-36) and Neck Disability Index (NDI). Thirty-six patients (19 male and 17 female) with mean age 49.6±7 years old who underwent successful single ACDF using self-locking stand-alone PEEK cage for symptomatic cervical DDD were selected for the study. Neck and Arm pain, as well as SF-36 and NDI were estimated preoperatively and 1, 3, 6, and 12 months postoperatively. Patients underwent preoperative and postoperative clinical, neurological and radiological evaluation. The clinical and radiological outcomes were satisfactory after a minimum 1-year follow-up. All results were statistically important (P<0.05), excluding improvement in NDI measured between 6 and 12 months. SF-36, Neck Pain, as well as Arm Pain featured gradual and constant improvement during follow-up, with best scores presenting at 12 months after surgery, while NDI reached its best at 6 months postoperatively. Generally, all scores showed improvement postoperatively during the different phases of the follow-up. Subsequently, ACDF using C-Plus cervical cage constitutes an effective method for cervical disc herniation treatment, in terms of postoperative improvement on pain levels and health-related quality of life and a safe alternative to the conventional method of treatment for cervical DDD.

  14. Influence of cervical bone mineral density on cage subsidence in patients following stand-alone anterior cervical discectomy and fusion.

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    Brenke, Christopher; Dostal, Martin; Scharf, Johann; Weiß, Christel; Schmieder, Kirsten; Barth, Martin

    2015-12-01

    Anterior cervical discectomy and fusion (ACDF) is a common procedure for the treatment of cervical degenerative diseases. However, cage subsidence remains a frequent problem. We therefore investigated if cage design and site-specific bone mineral density (BMD) contribute to the rate and direction of subsidence following ACDF. Patients were prospectively included and received two different cages (groups 1 and 2) using minimization randomization. The degree and direction of cage subsidence were determined using plain radiographs. Neck pain intensity on the visual analogue scale (VAS), the neck disability index (NDI), and the patient satisfaction index were recorded up to 12 months after surgery. 88 patients were analysed with a mean age of 53.7 ± 11.8 years. BMD values decreased in craniocaudal direction from 302.0 ± 62.2 to 235.5 ± 38.9 mg/cm(3). Both groups showed significant height gain after the operation (both p  0.05). Both groups showed improvement of VAS neck pain intensity (both p subsidence was similar, no correlations were found between cage subsidence and BMD or various clinical parameters. Implant geometry of both cages and variations of the operative procedure promoted a relatively high degree of cage subsidence. Further studies are necessary to identify a relation of BMD and subsidence using optimized implant geometry and by controlling additional intraoperative variables.

  15. Clinical and radiological outcomes after stand-alone ALIF for single L5-S1 degenerative discopathy using a PEEK cage filled with hydroxyapatite nanoparticles without bone graft.

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    Norotte, Gilles; Barrios, Carlos

    2018-05-01

    Recent improvements in cage designs with integral fixation and screw attachments have made stand-alone ALIF a viable option with several possible advantages. The aim of this study was to confirm the efficacy and safety of a PEEK cage filled with hydroxyapatite nanoparticles without adding a bone graft for stand-alone ALIF in the treatment of L5-S1 isolated degenerative disc discopathy (DDD). Sixty-five patients who required surgery for DDD were evaluated. Clinical outcome evaluations included back and leg pain (VAS), disability (Oswestry Disability Index), and patient satisfaction (Macnab's criteria). Radiological outcomes include the assessment of disc height, the L5-S1 intervertebral disc angle, and anterior intervertebral fusion through standard and functional sagittal X-rays of the lumbar spine. Clinical and radiological measurements were assessed 2, 6, 12, and 24 months after surgery. Clinical outcomes improved progressively and stabilized from 12- to 24-month follow-up. Final postoperative ODI scores showed a notable improvement (95%CI = 36.1-48.9 points; p < .001). Similarly, 24-month postoperative VAS scores revealed a significant decrease in pain (95%CI = 5.4-6.2; p < .001). The fusion rate was 95.4%. Anterior disc height was restored from 4.1 ± 3.2 mm at baseline to 9.5 ± 1.6 mm in the immediate postoperative period (p < .001). A small collapse (17.9%) of the disc height was detected from the 2- and 24-month follow-ups. Cage subsidence (more than 3 mm collapse) was detected in 4 cases (6.2%) and was related to cage size (more than 11 mm height; P < .05). There were no serious bone substitute-related adverse events and no revision surgeries. Stand-alone anterior lumbar interbody fusion using hydroxyapatite nanoparticles without an autologous bone graft is an effective and safe treatment option for L5-S1 degenerative pathology. Clinical outcomes were very satisfactory with a high fusion rate. Copyright © 2018

  16. A comparison of anterior cervical discectomy and fusion (ACDF) using self-locking stand-alone polyetheretherketone (PEEK) cage with ACDF using cage and plate in the treatment of three-level cervical degenerative spondylopathy: a retrospective study with 2-year follow-up.

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    Chen, Yuqiao; Lü, Guohua; Wang, Bing; Li, Lei; Kuang, Lei

    2016-07-01

    To evaluate the clinical efficacy and radiological outcomes of anterior cervical discectomy and fusion (ACDF) using self-locking polyetheretherketone (PEEK) cages for treatment of three-level cervical degenerative spondylopathy. Twenty-eight patients underwent three-level ACDF using self-locking stand-alone PEEK cages (group A), and 26 patients underwent three-level ACDF using cages and plate fixation (group B) were reviewed retrospectively. Clinical efficacy was evaluated by pre- and post-operative Japanese Orthopedic Association (JOA) scores and Neck Disability Index (NDI). The operation time, blood loss, surgical results according to Odom's criteria and post-operative dysphagia status were also recorded. Radiological outcomes including fusion, cervical Cobb's lordosis, fused segment angle, disc height, and cage subsidence were assessed. Clinical outcome measures such as dysphagia and fusion rate and the results of surgery evaluated according to Odom's criteria were not statistically significant (P > 0.05) between groups. The operation time was shorter and blood loss was less in group A (P  0.05). Post-operative cage subsidence, the loss of disc height, cervical lordosis and the fused segment angle were relatively higher in group A than group B (P < 0.05). ACDF using self-locking stand-alone cages showed similar clinical results as compared to ACDF using cages and plate fixation for the treatment of three-level cervical degenerative spondylopathy. However, potential long-term problems such as cage subsidence, loss of cervical lordosis and fused segment angle post-operatively were shown to be associated with patients who underwent ACDF using self-locking stand-alone cages.

  17. A Lower T1 Slope as a Predictor of Subsidence in Anterior Cervical Discectomy and Fusion with Stand-Alone Cages.

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    Lee, Su Hun; Lee, Jun Seok; Sung, Soon Ki; Son, Dong Wuk; Lee, Sang Weon; Song, Geun Sung

    2017-09-01

    Preoperative parameters including the T1 slope (T1S) and C2-C7 sagittal vertical axis (SVA) have been recognized as predictors of kyphosis after laminoplasty, which is accompanied by posterior neck muscle damage. The importance of preoperative parameters has been under-estimated in anterior cervical discectomy and fusion (ACDF) because there is no posterior neck muscle damage. We aimed to determine whether postoperative subsidence and pseudarthrosis could be predicted according to specific parameters on preoperative plain radiographs. We retrospectively analyzed 41 consecutive patients (male: female, 22: 19; mean age, 51.15±9.25 years) who underwent ACDF with a stand-alone polyether-ether-ketone (PEEK) cage (>1 year follow-up). Parameters including SVA, T1S, segmental angle and range of motion (ROM), C2-C7 cervical angle and ROM, and segmental inter-spinous distance were measured on preoperative plain radiographs. Risk factors of subsidence and pseudarthrosis were determined using multivariate logistic regression. Fifty-five segments (27 single-segment and 14 two-segment fusions) were included. The subsidence and pseudarthrosis rates based on the number of segments were 36.4% and 29.1%, respectively. Demographic data and fusion level were unrelated to subsidence. A greater T1S was associated with a lower risk of subsidence (p=0.017, odds ratio=0.206). A cutoff value of T1Ssubsidence (sensitivity: 70%, specificity: 68.6%). There were no preoperative predictors of pseudarthrosis except old age. A lower T1S (T1Ssubsidence following ACDF. Surgeons need to be aware of this risk factor and should consider various supportive procedures to reduce the subsidence rates for such cases.

  18. Comparison of a Stand-Alone Anchored Spacer Versus Plate-Cage Construct in the Treatment of Two Noncontiguous Levels of Cervical Spondylosis: A Preliminary Investigation.

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    Shi, Sheng; Zheng, Shuang; Li, Xin-Feng; Yang, Li-Li; Liu, Zu-De; Yuan, Wen

    2016-05-01

    The application of stand-alone anchored spacer (SAAS) in anterior cervical discectomy and fusion (ACDF) has been proven to be safe and effective to treat cervical spondylosis. Skip-level ACDF with SAAS, fusing only the involved levels without anterior plates, may be the optimal treatment. The aim of the study was to compare the clinical outcomes, radiologic results of SAAS, and plate-cage construct in the treatment of 2 noncontiguous levels of cervical spondylosis. A total of 65 patients with 2 noncontiguous levels of cervical spondylosis were included in the retrospective review of prospective collected data. The clinical and radiologic outcomes were assessed with the Japanese Orthopaedic Association score, Neck Disability Index, cervical alignment, and range of motion and disc height of intermediate segment, respectively. All the aforementioned parameters were compared before and after surgery in the respective group, which also were compared between the 2 groups. Complications also were recorded, and correlations between the surgical outcome and various factors were analyzed. No significant differences existed in clinical results between the 2 groups (P > 0.05). In addition, no statistical significance was observed in fusion rate, cervical alignment, and range of motion and disc height of intermediate segment, dysphagia, and hoarseness (P > 0.05). Preoperative Japanese Orthopaedic Association score and high-intensity signal in T2-weighted images were important predictors for surgical outcome. Skip-level ACDF with SAAS is a safe and effective treatment of 2 noncontiguous levels of cervical spondylosis without obvious contraindications, which can keep the IS intact, and have a low impact on the IS. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. Adult Degenerative Scoliosis with Spinal Stenosis Treated with Stand-Alone Cage via an Extreme Lateral Transpsoas Approach; a Case Report and Literature Review

    Directory of Open Access Journals (Sweden)

    Arvind von Keudell

    2015-04-01

    Full Text Available We report the case of a 73-year-old female with severe degenerative scoliosis and back and leg pain that wassuccessfully treated with stand- alone cages via an extreme lateral transpsoas approach. This patient had declinedopen surgery and instrumentation due to her advanced age concerns about potential side effects.

  20. Is the radiographic subsidence of stand-alone cages associated with adverse clinical outcomes after cervical spine fusion? An observational cohort study with 2-year follow-up outcome scoring.

    Science.gov (United States)

    Zajonz, Dirk; Franke, Anne-Catherine; von der Höh, Nicolas; Voelker, Anna; Moche, Michael; Gulow, Jens; Heyde, Christoph-Eckhard

    2014-01-01

    The stand-alone treatment of degenerative cervical spine pathologies is a proven method in clinical practice. However, its impact on subsidence, the resulting changes to the profile of the cervical spine and the possible influence of clinical results compared to treatment with additive plate osteosynthesis remain under discussion until present. This study was designed as a retrospective observational cohort study to test the hypothesis that radiographic subsidence of cervical cages is not associated with adverse clinical outcomes. 33 cervical segments were treated surgically by ACDF with stand-alone cage in 17 patients (11 female, 6 male), mean age 56 years (33-82 years), and re-examined after eight and twenty-six months (mean) by means of radiology and score assessment (Medical Outcomes Study Short Form (MOS-SF 36), Oswestry Neck Disability Index (ONDI), painDETECT questionnaire and the visual analogue scale (VAS)). Subsidence was observed in 50.5% of segments (18/33) and 70.6% of patients (12/17). 36.3% of cases of subsidence (12/33) were observed after eight months during mean time of follow-up 1. After 26 months during mean time of follow-up 2, full radiographic fusion was seen in 100%. MOS-SF 36, ONDI and VAS did not show any significant difference between cases with and without subsidence in the two-sample t-test. Only in one type of scoring (painDETECT questionnaire) did a statistically significant difference in t-Test emerge between the two groups (p = 0.03; α = 0.05). However, preoperative painDETECT score differ significantly between patients with subsidence (13.3 falling to 12.6) and patients without subsidence (7.8 dropped to 6.3). The radiological findings indicated 100% healing after stand-alone treatment with ACDF. Subsidence occurred in 50% of the segments treated. No impact on the clinical results was detected in the medium-term study period.

  1. Degenerative Cervical Disc Disease: Long-term Changes in Sagittal Alignment and Their Clinical Implications After Cervical Interbody Fusion Cage Subsidence: A Prospective Study With Standalone Lordotic Tantalum Cages.

    Science.gov (United States)

    Tomé-Bermejo, Félix; Morales-Valencia, Julián A; Moreno-Pérez, Javier; Marfil-Pérez, Juan; Díaz-Dominguez, Elena; Piñera, Angel R; Alvarez, Luis

    2017-06-01

    A retrospective, observational study of prospectively collected outcomes. To investigate the long-term clinical course of anterior cervical discectomy and fusion with interbody fusion cages (ACDF-IFC) with lordotic tantalum implants and to correlate the radiologic findings with the clinical outcomes, with special emphasis on the significance and the influence of implant subsidence. Cage subsidence is the most frequently reported complication after ACDF-IFC. However, most reports fail to correlate cage subsidence with lower fusion rates or with unsatisfactory clinical results. Forty-one consecutive patients with symptomatic degenerative cervical disk disease with failure of conservative treatment were included. All patients underwent 1-/2-level ACDF-IFC with lordotic tantalum implants. The mean follow-up was 4.91 years. The final follow-up fusion rate was 96.96% (32/33). The interspace height (IH) at the affected levels was significantly incremented after implant insertion, and despite a gradual loss in the height over time, the final follow-up IH was significantly higher than that measured preoperatively (Psubsidence (>3 mm) occurred in 11 disk spaces (26.82%). Preoperative and postoperative IH were significantly higher in subsidence patients; however, there was no difference in the final follow-up IH (P>0.05). Patients with ≥3 years of follow-up (n=29) did not demonstrate further significant subsidence beyond the second year. Regarding C1-C7 lordosis, the segmental Cobb angle, the cervical Visual Analogue Scale, and Neck Disability Index questionnaires, no difference between patients with or without final follow-up endplate subsidence was encountered. Until fusion occurs, tantalum cage settlement into the vertebral body is to be expected. Further subsidence could be the result of segmental adaptative changes. Graft subsidence did not affect the clinical outcome in any of our patients during long-term follow-up. The occurrence of dynamical implant subsidence had

  2. STANDALONE AVR PROGRAMMER

    Directory of Open Access Journals (Sweden)

    Wiedjaja Wiedjaja

    2007-10-01

    Full Text Available Article clarifies a research having goals to make AVR programming system that is portable, by makingsystem modul based on AVR AT8535 as AVR Programmer/Master and AT8515 asAVR Socket. The module instructionat first is hex file was sending from PC to AVR Programmer/Master that later will be saved to external memory. Afterthe hex file saved, programming process will not need help from PC anymore. The saved hex file that saved toexternal memory can be choosen that later will be written to AVR Socket. So, the AVR program can be donerepeatedly as long as data on external memory still saved. The standalone that was made can only programed AVRATMega 8515L. From the research ita can be conluded that on case of repeated program, Stand Alone AVR able tosave time 20% more faster that programming using AVR codevision.

  3. Stand-alone XLIF

    DEFF Research Database (Denmark)

    Hansen, E. J.; Simony, A.; Hummel, Stefan

    2015-01-01

    and clinical/radiological results in 22 patients treated with XLIF procedure for DS or degenerative disc disease (DDD). Material and methods: 22 consecutive patients with DS underwent surgery with the XLIF stand-alone procedure, with follow-up of 24 months. Clinical outcome scores were collected. Complications......Introduction: Adult thoracolumbar degeneration is an increasing challenge in the aging population. With age the progressive degeneration of the discs leads to an asymmetric collapse and a thoracolumbar coronal plane deformity, a degenerative scoliosis (DS). Aim: To evaluate the complication rate......-year follow-up, with a 31.8% revision rate. Due to the high revision rate we recommend supplementary posterior instrumentation, to achieve a higher fusion rate. When considering XLIF-stand-alone procedure for DS or DDD without supplemental posterior instrumentation, only single-level disease should...

  4. Stand-alone performance of a computer-assisted detection prototype for detection of acute pulmonary embolism: a multi-institutional comparison

    NARCIS (Netherlands)

    Wittenberg, R.; Peters, J. F.; Weber, M.; Lely, R. J.; Cobben, L. P. J.; Prokop, M.; Schaefer-Prokop, C. M.

    2012-01-01

    Objective: To assess whether the performance of a computer-assisted detection (CAD) algorithm for acute pulmonary embolism (PE) differs in pulmonary CT angiographies acquired at various institutions. Methods: In this retrospective study, we included 40 consecutive scans with and 40 without PE from 3

  5. Stand-alone performance of a computer-assisted detection prototype for detection of acute pulmonary embolism: a multi-institutional comparison.

    NARCIS (Netherlands)

    Wittenberg, R.; Peters, J.F.; Weber, M.; Lely, R.J.; Cobben, L.P.; Prokop, M.; Schaefer-Prokop, C.M.

    2012-01-01

    OBJECTIVE: To assess whether the performance of a computer-assisted detection (CAD) algorithm for acute pulmonary embolism (PE) differs in pulmonary CT angiographies acquired at various institutions. METHODS: In this retrospective study, we included 40 consecutive scans with and 40 without PE from 3

  6. Hydraulic testing of intravascular axial flow blood pump designs with a protective cage of filaments for mechanical cavopulmonary assist.

    Science.gov (United States)

    Kapadia, Jugal Y; Pierce, Kathryn C; Poupore, Amy K; Throckmorton, Amy L

    2010-01-01

    To provide hemodynamic support to patients with a failing single ventricle, we are developing a percutaneously inserted, magnetically levitated axial flow blood pump designed to augment pressure in the cavopulmonary circulation. The device is designed to serve as a bridge-to-transplant, bridge-to-recovery, bridge-to-hemodynamic stability, or bridge-to-surgical reconstruction. This study evaluated the hydraulic performance of three blood pump prototypes (a four-bladed impeller, a three-bladed impeller, and a three-bladed impeller with a four-bladed diffuser) whose designs evolved from previous design optimization phases. Each prototype included the same geometric protective cage of filaments, which stabilize the rotor within the housing and protect the housing wall from the rotating blades. All prototypes delivered pressure rises over a range of flow rates and rotational speeds that would be sufficient to augment hemodynamic conditions in the cavopulmonary circulation. The four-bladed impeller outperformed the two remaining prototypes by >40%; this design was able to generate a pressure rise of 4-28 mm Hg for flow rates of 0.5-10 L/min at rotational speeds of 4,000-7,000 RPM. Successful development of this blood pump will provide clinicians with a feasible therapeutic option for mechanically supporting the failing Fontan.

  7. Switching Vertical to Horizontal Graphene Growth Using Faraday Cage-Assisted PECVD Approach for High-Performance Transparent Heating Device.

    Science.gov (United States)

    Qi, Yue; Deng, Bing; Guo, Xiao; Chen, Shulin; Gao, Jing; Li, Tianran; Dou, Zhipeng; Ci, Haina; Sun, Jingyu; Chen, Zhaolong; Wang, Ruoyu; Cui, Lingzhi; Chen, Xudong; Chen, Ke; Wang, Huihui; Wang, Sheng; Gao, Peng; Rummeli, Mark H; Peng, Hailin; Zhang, Yanfeng; Liu, Zhongfan

    2018-02-01

    Plasma-enhanced chemical vapor deposition (PECVD) is an applicable route to achieve low-temperature growth of graphene, typically shaped like vertical nanowalls. However, for transparent electronic applications, the rich exposed edges and high specific surface area of vertical graphene (VG) nanowalls can enhance the carrier scattering and light absorption, resulting in high sheet resistance and low transmittance. Thus, the synthesis of laid-down graphene (LG) is imperative. Here, a Faraday cage is designed to switch graphene growth in PECVD from the vertical to the horizontal direction by weakening ion bombardment and shielding electric field. Consequently, laid-down graphene is synthesized on low-softening-point soda-lime glass (6 cm × 10 cm) at ≈580 °C. This is hardly realized through the conventional PECVD or the thermal chemical vapor deposition methods with the necessity of high growth temperature (1000 °C-1600 °C). Laid-down graphene glass has higher transparency, lower sheet resistance, and much improved macroscopic uniformity when compare to its vertical graphene counterpart and it performs better in transparent heating devices. This will inspire the next-generation applications in low-cost transparent electronics. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Artrodese cervical anterior em três e quatro níveis com dispositivo intersomático não associado à placa cervical Artrodesis cervical anterior en tres y cuatro niveles con dispositivo intersomático no asociado a placa cervical Anterior cervical arthrodesis for three and four levels using stand-alone interbody cages without cervical plates

    Directory of Open Access Journals (Sweden)

    Marcel Luiz Benato

    2009-06-01

    en tercer y cuarto niveles; dolor axial y/o irradiada; con mínimo seis meses de postoperatorio. El criterio de exclusión fue la presencia de inestabilidad cervical traumática. Fueron evaluadas las tasas de consolidación, la presencia de síntomas, la tasa de complicaciones y la posición de los dispositivos intersomáticos (subsidente después de seis meses. RESULTADOS: todos los pacientes obtuvieron consolidación en tres meses, sin embargo, dos pacientes presentaron el fenómeno de subsidente, o sea, migración con consolidación en cifosis, sin alterar los resultados clínicos y la consolidación de la artrodesis a los seis meses de postoperatorio. Los pacientes presentaron mejoría del dolor preoperatorio y solo tres (15% presentaron dolor residual. No hubo complicaciones mayores. El tiempo de hospitalización fue de dos días. No fue utilizada inmovilización rígida en el postoperatorio. CONCLUSIÓN: fue obtenida consolidación con esta técnica en todos los casos. La técnica se mostró segura y promovió buenos resultados radiológicos y clínicos.evaluate the rates of fusion of the anterior cervical discectomy and arthrodesis for three and four levels using interbody cages (stand-alone without cervical plates six months after post-operative. METHODS: from November 2005 to July 2008, 20 patients were treated as proposed. The inclusion criteria were: cervical degenerative disease of three and four levels; axial and/or irradiated pain at least six months of follow-up. The exclusion criteria were: cervical traumatic instability. The fusion rate, clinical symptoms, rate of complications and the implant position were evaluated six months after post-operative. RESULTS: results were favorable in 100% of the patients, with residual pain in two cases. Fusion was found in 100% of the patients, except for two cases with minimum subsidence and fusion in a slight kyphotic position. There were not significant complications. The discharge of the hospital was performed

  9. Self-Assembled Pyridine-Dipyrrolate Cages.

    Science.gov (United States)

    Zhang, Huacheng; Lee, Juhoon; Lammer, Aaron D; Chi, Xiaodong; Brewster, James T; Lynch, Vincent M; Li, Hao; Zhang, Zhan; Sessler, Jonathan L

    2016-04-06

    An inherently nonlinear pyridine dipyrrolate ligand, namely 2,6-bis(3,4-diethyl-5-carboxy-1H-pyrrol-2yl)pyridine (compound 1), is able to distinguish between different zinc(II) cation sources, namely Zn(acac)2 and Zn(OAc)2, respectively. This differentiation is manifest both in terms of the observed fluorescent behavior in mixed organic media and the reaction chemistry. Treatment of 1 with Zn(acac)2 gives rise to a cage dimer, cage-1, wherein two molecules of compound 1 act as double bridging units to connect two individual cage subunits. As inferred from X-ray crystallographic studies, this cage system consists of discrete zinc dimers with hydroxide bridges that, with the assistance of bound DMF solvent molecules, serve to fix the geometry and orientation of the pyridine dipyrrolate building blocks. When a different zinc source, Zn(OAc)2, is used to carry out an ostensibly similar complexation reaction with compound 1, an acetate-bridged 1D abacus-like cage polymer is obtained as inferred from X-ray diffraction analysis. This extended solid state structure, cage-2, contains individual zinc dimer cage submits and appears stabilized by solvent molecules (DMF) and the counteranion (acetate). Rod-like assemblies are also observed by DLS and SEM. This construct, in contrast to cage-1, proved fluorescent in mixed organic media. The structure of the ligand itself (i.e., in the absence of Zn(II)) was confirmed by X-ray crystallographic analysis and was found to assemble into a supramolecular polymer. Conversion to a dimer form was seen upon the addition of TBAOAc. On the basis of the metric parameters, the structures seen in the solid state are stabilized via hydrogen bonding interactions involving solvent molecules.

  10. Spinal fusion using adipose stem cells seeded on a radiolucent cage filler : a feasibility study of a single surgical procedure in goats

    NARCIS (Netherlands)

    Kroeze, Robert J.; Smit, Theo H.; Vergroesen, Pieter P.; Bank, Ruud A.; Stoop, Reinout; van Rietbergen, Bert; van Royen, Barend J.; Helder, Marco N.

    2015-01-01

    To assess the feasibility of a one-step surgical concept, employing adipose stem cells (ASCs) and a novel degradable radiolucent cage filler (poly-L-lactide-co-caprolactone; PLCL), within polyetheretherketone cages in a stand-alone caprine spinal fusion model. A double-level fusion study was

  11. Spinal fusion using adipose stem cells seeded on a radiolucent cage filler: a feasibility study of a single surgical procedure in goats

    NARCIS (Netherlands)

    Kroeze, R.J.; Smit, T.H.; Vergroesen, P.P.A.; Bank, R.A.; Stoop, R.; van Rietbergen, B.; van Royen, B.J.; Helder, M.N.

    2015-01-01

    Purpose: To assess the feasibility of a one-step surgical concept, employing adipose stem cells (ASCs) and a novel degradable radiolucent cage filler (poly-L-lactide-co-caprolactone; PLCL), within polyetheretherketone cages in a stand-alone caprine spinal fusion model. Methods: A double-level fusion

  12. Spinal fusion using adipose stem cells seeded on a radiolucent cage filler: a feasibility study of a single surgical procedure in goats

    NARCIS (Netherlands)

    Kroeze, R.J.; Smit, T.H.; Vergroesen, P.P.; Bank, R.A.; Stoop, R.; Rietbergen, B. van; Royen, B.J. van; Helder, M.N.

    2015-01-01

    PURPOSE: To assess the feasibility of a one-step surgical concept, employing adipose stem cells (ASCs) and a novel degradable radiolucent cage filler (poly-L-lactide-co-caprolactone; PLCL), within polyetheretherketone cages in a stand-alone caprine spinal fusion model. METHODS: A double-level fusion

  13. Spinal fusion using adipose stem cells seeded on a radiolucent cage filler: a feasibility study of a single surgical procedure in goats

    NARCIS (Netherlands)

    Kroeze, Robert J.; Smit, Theo H.; Vergroesen, Pieter P.; Bank, Ruud A.; Stoop, Reinout; van Rietbergen, Bert; van Royen, Barend J.; Helder, Marco N.

    2015-01-01

    To assess the feasibility of a one-step surgical concept, employing adipose stem cells (ASCs) and a novel degradable radiolucent cage filler (poly-L-lactide-co-caprolactone; PLCL), within polyetheretherketone cages in a stand-alone caprine spinal fusion model. A double-level fusion study was

  14. The Stand-alone Heliostat

    International Nuclear Information System (INIS)

    Garcia Navajas, G. I.; Egea Gea, A.

    2000-01-01

    The first Autonomous Heliostat has been developed by CIEMAT at PSA facilities in Almeria. This heliostat is an innovative approach to reducing the civil engineering work costs in heliostat fields of central tower plants. Channels, cables and other electric elements have been eliminated in the new heliostat. Thus, one 70-nr, classical T glass/metal heliostat has been adapted to include all the new stand-alone concept components. A PV system is able to drive two sun-tracking DC motors between 5 and 24Vdc, 0 and 15A. The heliostat communicates with the control room 400-m away by using a radio-modem working at 9600 baud. An anemometer, a wind switcher, light and ambient temperature sensors have been installed on the heliostat for self-protection decision-making. A PV panel integrated into the heliostat reflecting surface, eliminates cabling and other elements required for a conventional power supply. Communication lines between master control and local control have been replaced by radio-modem. Testing has validated the technical feasibility of the prototype and quantified the real consumption and efficiencies of new elements. The extra costs produced.by the autonomous concepts are compared with the cost of civil work in conventional heliostat field. (Author) 8 refs

  15. Anterior Lumbar Interbody Fusion Integrated Screw Cages: Intrinsic Load Generation, Subsidence, and Torsional Stability.

    Science.gov (United States)

    Assem, Yusuf; Pelletier, Matthew H; Mobbs, Ralph J; Phan, Kevin; Walsh, William R

    2017-05-01

    To perform a repeatable idealized in vitro model to evaluate the effects of key design features and integrated screw fixation on unloaded surface engagement, subsidence, and torsional stability. We evaluated four different stand-alone anterior lumbar interbody fusion (ALIF) cages with two, three, and four screw designs. Polyurethane (saw-bone) foam blocks were used to simulate the vertebral bone. Fuji Film was used to measure the contact footprint, average pressure, and load generated by fixating the cages with screws. Subsidence was tested by axially loading the constructs at 10 N/s to 400 N and torsional load was applied +/-1 Nm for 10 cycles to assess stability. Outcome measures included total subsidence and maximal torsional angle range. Cages 1, 2, and 4 were symmetrical and produced similar results in terms of contact footprint, average pressure, and load. The addition of integrated screws into the cage-bone block construct demonstrated a clear trend towards decreased subsidence. Cage 2 with surface titanium angled ridges and a keel produced the greatest subsidence with and without screws, significantly more than all other cages ( P < 0.05). Angular rotation was not significantly affected by the addition of screws ( P < 0.066). A statistically significant correlation existed between subsidence and reduced angular rotation across all cage constructs ( P = 0.018). Each stand-alone cage featured unique surface characteristics, which resulted in differing cage-foam interface engagement, influencing the subsidence and torsional angle. Increased subsidence significantly reduced the torsional angle across all cage constructs. © 2017 Chinese Orthopaedic Association and John Wiley & Sons Australia, Ltd.

  16. A Standalone Vision Impairments Simulator for Java Swing Applications

    Science.gov (United States)

    Oikonomou, Theofanis; Votis, Konstantinos; Korn, Peter; Tzovaras, Dimitrios; Likothanasis, Spriridon

    A lot of work has been done lately in an attempt to assess accessibility. For the case of web rich-client applications several tools exist that simulate how a vision impaired or colour-blind person would perceive this content. In this work we propose a simulation tool for non-web JavaTM Swing applications. Developers and designers face a real challenge when creating software that has to cope with a lot of interaction situations, as well as specific directives for ensuring an accessible interaction. The proposed standalone tool will assist them to explore user-centered design and important accessibility issues for their JavaTM Swing implementations.

  17. Commercial cage fish culture

    OpenAIRE

    Aigbadon, B.V.

    1987-01-01

    With increasing emphasis in Nigeria on aquaculture as an alternative to dwindling artisanal fishing and scarce foreign exchange for fish import, cage fish culture, is a more profitable aquaculture practice than pond culture. It appears to be one of the most viable business ventures with minimum risks. It is a highly recommendable project

  18. Interpenetrated Cage Structures.

    Science.gov (United States)

    Frank, Marina; Johnstone, Mark D; Clever, Guido H

    2016-09-26

    This Review covers design strategies, synthetic challenges, host-guest chemistry, and functional properties of interlocked supramolecular cages. Some dynamic covalent organic structures are discussed, as are selected examples of interpenetration in metal-organic frameworks, but the main focus is on discrete coordination architectures, that is, metal-mediated dimers. Factors leading to interpenetration, such as geometry, flexibility and chemical makeup of the ligands, coordination environment, solvent effects, and selection of suitable counter anions and guest molecules, are discussed. In particular, banana-shaped bis-pyridyl ligands together with square-planar metal cations have proven to be suitable building blocks for the construction of interpenetrated double-cages obeying the formula [M4 L8 ]. The peculiar topology of these double-cages results in a linear arrangement of three mechanically coupled pockets. This allows for the implementation of interesting guest encapsulation effects such as allosteric binding and template-controlled selectivity. In stimuli-responsive systems, anionic triggers can toggle the binding of neutral guests or even induce complete structural conversions. The increasing structural and functional complexity in this class of self-assembled hosts promises the construction of intelligent receptors, novel catalytic systems, and functional materials. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. EELA Operations: A standalone regional dashboard implementation

    OpenAIRE

    L'Orphelin, Cyril; Cordier, Hélène; Reynaud, Sylvain; Lins, Marcos; Loikkanen, Sinika; Lequeux, Olivier; Veyre, Pierre

    2013-01-01

    International audience; Grid operators in EGEE use a dedicated dashboard as their central operational tool, stable and scalable for the last 5 years despite continuous upgrade from specifications by users, monitoring tools or data providers. In EGEE-III, regionalisation of operations led the tool developers to conceive a standalone instance of this tool. Hereby, we will present the concept and the EELA-II implementation. Indeed, there-engineering of this tool led to an easily deployable packa...

  20. Cage-based performance capture

    CERN Document Server

    Savoye, Yann

    2014-01-01

    Nowadays, highly-detailed animations of live-actor performances are increasingly easier to acquire and 3D Video has reached considerable attentions in visual media production. In this book, we address the problem of extracting or acquiring and then reusing non-rigid parametrization for video-based animations. At first sight, a crucial challenge is to reproduce plausible boneless deformations while preserving global and local captured properties of dynamic surfaces with a limited number of controllable, flexible and reusable parameters. To solve this challenge, we directly rely on a skin-detached dimension reduction thanks to the well-known cage-based paradigm. First, we achieve Scalable Inverse Cage-based Modeling by transposing the inverse kinematics paradigm on surfaces. Thus, we introduce a cage inversion process with user-specified screen-space constraints. Secondly, we convert non-rigid animated surfaces into a sequence of optimal cage parameters via Cage-based Animation Conversion. Building upon this re...

  1. Stand-alone photovoltaic applications. Lessons learned

    International Nuclear Information System (INIS)

    Loois, G.; Van Hemert, B.

    1999-02-01

    The IEA Photovoltaic Power Systems Programme (PVPS) is one of the collaborative R and D agreements established within the IEA. The objective of Task III is to promote and facilitate the exchange of information and experiences in the field of PV Systems in Stand-alone and Island Applications (SAPV). The book focuses on the practical experiences gained, and does not aim to provide a complete manual on SAPV. When Task III started its activities in 1993, a collection of 50 'State of the art' projects was published in the book 'Examples of Stand-Alone Photovoltaic Systems'. This publication marked the base line for the work of the task. Now, in 1998, the showcases from each country demonstrate the lessons learned in five years of cooperation. The book consists of two parts. The first part contains eight chapters dealing with a specific aspect of stand-alone PV. The second part introduces 14 national showcase projects in a systematic presentation. Each chapter and showcase can be read independently from the rest of the book. Chapter 2, contributed by The Netherlands, analyses the market for stand-alone PV systems. It gives an overview of the 'traditional' application of stand-alone PV, which is the electrification of remote buildings and which has been addressed in depth in other publications. The focus is on the market niches of service applications that are also interesting for more densely populated areas, e.g. in industrialised countries. The United Kingdom illustrates the economic aspects in Chapter 3. Cost comparisons are made, but more important is the illustration of the non-financial considerations that make PV the preferred choice as a power source for many applications. Switzerland explores in Chapter 4 (financing aspects) different financing mechanisms, and financial policies used to overcome the initial cost barrier. Most of these approaches have been applied in developing countries rather than in the western world. Using various examples from all over the

  2. standalone general purpose data logger design and implementation

    African Journals Online (AJOL)

    eobe

    PC via an RS-232 serial port. 232 serial port. 232 serial port. The standalone general purpose data logger centered on a single. The standalone general purpose data logger centered on a single microcontroller unit (MCU microcontroller unit (MCU) the PIC18F4520. the PIC18F4520. the PIC18F4520. The circuit takes an ...

  3. 39 CFR 122.2 - Stand-alone special services.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Stand-alone special services. 122.2 Section 122.2 Postal Service UNITED STATES POSTAL SERVICE POST OFFICE SERVICES [DOMESTIC MAIL] SERVICE STANDARDS FOR MARKET-DOMINANT SPECIAL SERVICES PRODUCTS § 122.2 Stand-alone special services. (a) The service standard...

  4. Lumbar sagittal contour after posterior interbody fusion: threaded devices alone versus vertical cages plus posterior instrumentation.

    Science.gov (United States)

    Klemme, W R; Owens, B D; Dhawan, A; Zeidman, S; Polly, D W

    2001-03-01

    An observational radiographic study examining lumbar sagittal contour of patients undergoing posterior interbody arthrodesis. To compare operative alterations of lumbar sagittal contour after posterior interbody fusion using threaded interbody devices alone versus vertical cages combined with posterior compression instrumentation. Technique-related alterations of lumbar sagittal contour during interbody arthrodesis have received little attention in the spinal literature. Standing lumbar radiographs were measured for preoperative and postoperative segmental lordosis at levels undergoing posterior interbody arthrodesis using either stand-alone side-by-side threaded devices or vertical cages combined with posterior transpedicular compression instrumentation. Sagittal plane segmental correction (or loss of correction) was calculated and statistically compared. The radiographs of 30 patients (34 spinal segments) undergoing lumbar or lumbosacral arthrodesis were compared. Seventeen patients (18 segments) had undergone interbody fusion using threaded cages,whereas 13 patients (16 segments) underwent fusion using vertically oriented mesh cages combined with posterior compression instrumentation. Preoperative segmental lordosis averaged 8 degrees for both groups. For patients undergoing fusion with threaded cages, there was a mean lordotic loss of 3 degrees/segment. For patients undergoing fusion with vertically oriented mesh cages combined with posterior compression instrumentation,there was a mean lordotic gain of 5 degrees/segment. This difference in segmental sagittal plane contour was highly significant (P = 0.00). Threaded fusion devices placed under interbody distraction with the endplates parallel fail to preserve or reestablish segmental lordosis. Vertical cages, however, when combined with posterior compression instrumentation, not only maintain segmental lordosis, but also can correct sagittal plane deformity.

  5. Cage culture of sea bass in Malaysia

    OpenAIRE

    1994-01-01

    The article discusses the cage culture practice of sea bass (Lates calcarifer) in Malaysia. Problems on feed and seed supply and overcrowding are also discussed. Despite these problems, seabass cage culture still continuously booms.

  6. Effect of wind generation system types on Micro-Grid (MG) fault performance during both standalone and grid connected modes

    International Nuclear Information System (INIS)

    Kamel, Rashad M.

    2014-01-01

    Highlights: • This paper evaluated the effects of different wind system types on fault performance of Micro-Grid. • Both standalone and grid connected modes are considered. • The MG earthing system configuration is taken in consideration. - Abstract: Recently, there are three wind generation (WG) system types. The first type is called Fixed Speed Wind Generation (FSWG) system, which employs squirrel cage induction generators. Double Fed Induction Generator (DFIG) is utilized in the second type. The third type is called Full Converter Wind Generation (FCWG) system, which is interfaced with Micro-Grid (MG) through a back to back converter. During fault occurrence, each WG has its performance and characteristics which are determined by the generator physical characteristics and the MG earthing system configuration. For some WG types, the fault current depends also on the control algorithm of the power converter. The main target of this paper is to investigate and estimate how the fault performance of MG during both standalone and grid-connected modes is influenced by the type of WG. It is found during standalone mode that the type of the employed WG has a dominant impact on the MG performance under fault disturbance. On the contrary, the type of the employed WG has a negligible effect on the MG fault performance during grid-connected mode. This is because the main grid contributes most of the fault current. Effects of earthing system type on MG performance are highlighted

  7. A Mobile Phone Faraday Cage

    Science.gov (United States)

    French, M. M. J.

    2011-01-01

    A Faraday cage is an interesting physical phenomenon where an electromagnetic wave can be excluded from a volume of space by enclosure with an electrically conducting material. The practical application of this in the classroom is to block the signal to a mobile phone by enclosing it in a metal can. The background of the physics behind this is…

  8. The Effect of Cervical Interbody Cage Morphology, Material Composition, and Substrate Density on Cage Subsidence.

    Science.gov (United States)

    Suh, Paul B; Puttlitz, Christian; Lewis, Chad; Bal, B Sonny; McGilvray, Kirk

    2017-02-01

    Interbody cages used in spinal fusion surgery can subside into the adjacent vertebral bodies after implantation, leading to loss of spinal height, malalignment, and possible radicular symptoms. Several factors may contribute to cage subsidence. This in vitro investigation examined the possible contribution of substrate density, cage contact area (ie, cage footprint), cage filling, cage end plate surface texture, and cage material composition on the magnitude of subsidence. Commercially available cervical interbody cages of two sizes (16 × 12 mm and 17 × 14 mm) were implanted between foam blocks of two different densities and were cyclically loaded. Cages were made of titanium alloy (Ti4Al6V), silicon nitride ceramic (Si3N4), or polyether ether ketone (n = 8 cages of each material type). Additional testing was performed on Si3N4 cages of the smaller size with nontextured surfaces and with filled cores. Subsidence measurements showed that lower foam density had the greatest influence on subsidence, followed by smaller cage footprint. Cage material had no effect on subsidence. In the additional testing of small-footprint Si3N4 cages, the cages in which the core was filled with a load-bearing porous material had less subsidence in lower-density foam than the cages with an empty core had, whereas cage end plate surface texture had no effect on subsidence. Ranking of the relative impact of these factors indicated that substrate density had the greatest contribution to the measured subsidence (approximately 1.7 times and approximately 67 times greater than the contributions of cage footprint area and material, respectively). The contribution of cage footprint area to subsidence was found to be 40 times greater than the contribution of cage material to subsidence.

  9. Polymers containing borane or carborane cage compounds and related applications

    Science.gov (United States)

    Bowen, III, Daniel E; Eastwood, Eric A

    2013-04-23

    Polymers comprising residues of cage compound monomers having at least one polyalkoxy silyl substituent are provided. The cage compound monomers are selected from borane cage compound monomers comprising at least 7 cage atoms and/or carborane cage compound monomers comprising 7 to 11 cage compound monomers. Such polymers can further comprise one or more reactive matrices and/or co-monomers covalently bound with the cage compound monomer residues. Articles of manufacture comprising such polymers are also disclosed.

  10. Listening to Cage: Nonintentional philosophy and music

    Directory of Open Access Journals (Sweden)

    Richard Fleming

    2016-12-01

    Full Text Available Listening to Cage: Nonintentional Philosophy and Music threads together the writings of ordinary language philosophy and the music of John Cage, responding specifically to requests made by Cage and Stanley Cavell. While many texts downplay or ignore the philosophical demands in Cage’s music and other texts find grandiose spiritual and philosophical material tied to his work, this text rejects both efforts. It challenges the basic directions of the growing secondary source material on Cage, finding it largely contrary to what Cage himself and his music teaches. That secondary material constantly offers an intentional approach to the music which is to make Cage understandable or easier to understand. The present text makes him appropriately difficult and basically unapproachable, asking the reader for serious acknowledgment of what Cage says he does, namely, “I have nothing to say and I am saying it.” While there is little hope of stopping the Cage industry that academia and publishers have grown, this text wishes at least to try to slow it down. The footnotes of this text include direct conversation material with Cage from the 1980s and 1990s regarding many subjects—his own compositions, our life struggles, remarks on Wittgenstein, Thoreau, philosophy, and music—all with a new context for their hearing.

  11. From Coordination Cages to a Stable Crystalline Porous Hydrogen-Bonded Framework

    Energy Technology Data Exchange (ETDEWEB)

    Ju, Zhanfeng [State Key Lab of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, CAS, Fuzhou 350002 P. R. China; Liu, Guoliang [State Key Lab of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, CAS, Fuzhou 350002 P. R. China; Chen, Yu-Sheng [ChemMatCARS, Center for Advanced Radiation Sources, The University of Chicago, Argonne Illinois 60439 USA; Yuan, Daqiang [State Key Lab of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, CAS, Fuzhou 350002 P. R. China; Chen, Banglin [Department of Chemistry, University of Texas at San Antonio, San Antonio Texas 78249-0698 USA

    2017-03-20

    A stable framework has been constructed through multiple charge-assisted H-bonds between cationic coordination cages and chloride ions. The framework maintained its original structure upon desolvation, which has been established by single-crystal structure analysis. This is the first fully characterized stable porous framework based on coordination cages after desolvation, with a moderately high Brunauer–Emmett–Teller (BET) surface area of 1201 m2 g-1. This work will not only give a light to construct stable porous frameworks based on coordination cages and thus broaden their applications, but will also provide a new avenue to the assembly of other porous materials such as porous organic cages and hydrogen-bonded organic frameworks (HOFs) through non covalent bonds.

  12. Synchronisation of two separate zones in a standalone microgrid

    Directory of Open Access Journals (Sweden)

    Ying-Yi Hong

    2017-06-01

    Full Text Available Standalone microgrids that comprise distributed generation sources (DGSs or energy storage systems (ESSs exist on off-shore islands or remote areas. When a fault occurs in a standalone microgrid, the microgrid is separated into several zones with pre-specified DGS or ESS supplying power to local loads. After the fault is cleared, the three-phase voltages and frequencies may differ among these zones. To restore the original microgrid topology, these zones must be reconnected to each other by synchronisation. A synchronisation controller of the DGS/ESS that accounts for slightly different three-phase voltages and frequencies in two separate zones is presented. The Clark transform and Mamdani fuzzy rules are used to implement the controller, providing fast and seamless synchronisation. Simulation results using a standalone microgrid show the practical applicability of the proposed method.

  13. Posterior lumbar interbody fusion with stand-alone Trabecular Metal cages for repeatedly recurrent lumbar disc herniation and back pain

    NARCIS (Netherlands)

    Lequin, Michiel B.; Verbaan, Dagmar; Bouma, Gerrit J.

    2014-01-01

    Patients with recurrent sciatica due to repeated reherniation of the intervertebral disc carry a poor prognosis for recovery and create a large burden on society. There is no consensus about the best treatment for this patient group. The goal of this study was to evaluate the 12-month results of the

  14. Models for a stand-alone PV system

    DEFF Research Database (Denmark)

    Hansen, A.D.; Sørensen, Poul Ejnar; Hansen, L.H.

    2001-01-01

    This report presents a number of models for modelling and simulation of a stand-alone photovoltaic (PV) system with a battery bank verified against a system installed at Risø National Laboratory. The work has been supported by the Danish Ministry ofEnergy, as a part of the activities in the Solar...... Energy Centre Denmark. The study is carried out at Risø National Laboratory with the main purpose to establish a library of simple mathematical models for each individual element of a stand-alone PVsystem, namely solar cells, battery, controller, inverter and load. The models for PV module and battery...

  15. Design of a reliable and low-cost stand-alone micro hydropower station

    Energy Technology Data Exchange (ETDEWEB)

    Kusakana, K.; Munda, J.L. [Tshwane Univ. of Technology, Pretoria (South Africa)

    2008-07-01

    A stand-alone micro-hydropower station was presented. The plant was comprised of a squirrel cage induction machine coupled to a Kaplan water turbine. Power converters were used to control the variable frequency and voltage outputs of the generator caused by variations in water flow. The hydropower plant was installed a farm in the Kwazulu-Natal region of South Africa, and was designed to provide electricity in relation to the low power demand of users in the region as well as according to the site's hydrology and topology. Load forecasts for the 8 houses using the system were conducted. A generator with a higher output than the average power needed to feed the load was selected in order to ensure load supply during peak demand. The system was designed to shore energy generated during off-peak periods in batteries. An AC-DC-AC converter was used as an interface between the generator and the load in order to ensure voltage and frequency stabilization. Simulations of plant components were conducted to demonstrate output power supply during water flow variations. Results of the modelling study indicated that power converters are needed to stabilize generator outputs. The hydropower design is a cost-effective means of supplying power to low-income households. 10 refs., 2 tabs., 7 figs.

  16. COATING ALTERNATIVES GUIDE (CAGE) USER'S GUIDE

    Science.gov (United States)

    The guide provides instructions for using the Coating Alternatives GuidE (CAGE) software program, version 1.0. It assumes that the user is familiar with the fundamentals of operating an IBM-compatible personal computer (PC) under the Microsoft disk operating system (MS-DOS). CAGE...

  17. Jules Verne's Metaphor of the Iron Cage

    NARCIS (Netherlands)

    Ossewaarde, Marinus R.R.

    2010-01-01

    Max Weber's concept of the iron cage has become a byword in the scholarly world since the publication in 1930 of Talcott Parsons’ translation of The Protestant Ethic and the Spirit of Capitalism. What is less well-known is that Jules Verne had earlier used the iron cage metaphor in Twenty Thousand

  18. Rescue Implantation of Expandable Cages for Severe Osteolysis and Cage Dislocation in the Lumbosacral Junction.

    Science.gov (United States)

    Schatlo, Bawarjan; Rohde, Veit; Solomiichuk, Volodymyr; von Eckardstein, Kajetan; Behm, Timo

    2017-11-01

    Osteolysis and implant loosening are commonly encountered problems after spinal instrumentation. In a patient who had previously undergone a posterior lumbar interbody fusion procedure, fusion did not occur, and a secondary cage dislocation led to an impingement of the L5 nerve root with severe radiculopathy. Revision surgery was performed. Intraoperatively, osteolysis was found to be so severe that conventional cages did not fill the void to allow for sufficient anterior column support. We used expandable transforaminal lumbar interbody fusion cages and implanted them bilaterally to replace the dislodged posterior lumbar interbody fusion cages. Clinical follow-up was uneventful. Imaging performed at 1 year showed satisfactory cage position and fusion. We propose the use of cages with the ability of ventral distraction in similar rescue interventions with cage dislocation and bone resorption. This may prevent a second surgery via a ventral approach. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Standalone General Purpose Data Logger Design and Implementation

    African Journals Online (AJOL)

    This paper describes the design of a general purpose data logger that is compatible with a variety of transducers, potentially permitting the measurement and recording of a wide range of phenomena. The recorded data can be retrieved to a PC via an RS-232 serial port. The standalone general purpose data logger ...

  20. PMBLDCG based stand-alone wind energy conversion system for ...

    African Journals Online (AJOL)

    This paper deals with a permanent magnet brushless DC generator (PMBLDCG) based stand-alone wind energy conversion system (WECS) for small scale power generation. A buck-boost DC-DC converter is used for controlling the PMBLDCG speed to achieve optimum energy output from the wind turbine without sensing ...

  1. The stand-alone test and decreasing serial cost sharing

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Thorlund-Petersen, Lars

    2000-01-01

    The rule of decreasing serial cost sharing defined in de Frutos [1] over the class of concave cost functions may violate the important stand-alone test. Sufficient conditions for the test to be satisfied are given, in terms of individual rationality as well as coalitional stability...

  2. Stand-alone flat-plate photovoltaic power systems: System sizing and life-cycle costing methodology for Federal agencies

    Science.gov (United States)

    Borden, C. S.; Volkmer, K.; Cochrane, E. H.; Lawson, A. C.

    1984-01-01

    A simple methodology to estimate photovoltaic system size and life-cycle costs in stand-alone applications is presented. It is designed to assist engineers at Government agencies in determining the feasibility of using small stand-alone photovoltaic systems to supply ac or dc power to the load. Photovoltaic system design considerations are presented as well as the equations for sizing the flat-plate array and the battery storage to meet the required load. Cost effectiveness of a candidate photovoltaic system is based on comparison with the life-cycle cost of alternative systems. Examples of alternative systems addressed are batteries, diesel generators, the utility grid, and other renewable energy systems.

  3. A review on sizing methodologies of photovoltaic array and storage battery in a standalone photovoltaic system

    International Nuclear Information System (INIS)

    Khatib, Tamer; Ibrahim, Ibrahim A.; Mohamed, Azah

    2016-01-01

    Highlights: • We review the current methods for sizing standalone PV systems. • We review the current criteria adapted in sizing standalone PV systems. • We review current method for sizing battery in standalone PV systems. - Abstract: The reliance of future energy demand on standalone PV system is based on its payback period and particular electrical grid parity prices. This highlights the importance for optimum and applicable methods for sizing these systems. Moreover, the designers are being more sensitive toward simple and reliable sizing models for standalone PV system. This paper proposes a review on important knowledge that needs to be taken into account while designing and implementing standalone PV systems. Such a knowledge includes configurations of standalone photovoltaic system, evaluation criteria for unit sizing, sizing methodologies. Moreover, this review provides highlights on challenges and limitations of standalone PV system size optimization techniques.

  4. Fracture of the L-4 vertebral body after use of a stand-alone interbody fusion device in degenerative spondylolisthesis for anterior L3-4 fixation.

    Science.gov (United States)

    Kwon, Yoon-Kwang; Jang, Ju-Hee; Lee, Choon-Dae; Lee, Sang-Ho

    2014-06-01

    Many studies attest to the excellent results achieved using anterior lumbar interbody fusion (ALIF) for degenerative spondylolisthesis. The purpose of this report is to document a rare instance of L-4 vertebral body fracture following use of a stand-alone interbody fusion device for L3-4 ALIF. The patient, a 55-year-old man, had suffered intractable pain of the back, right buttock, and left leg for several weeks. Initial radiographs showed Grade I degenerative spondylolisthesis, with instability in the sagittal plane (upon 15° rotation) and stenosis of central and both lateral recesses at the L3-4 level. Anterior lumbar interbody fusion of the affected vertebrae was subsequently conducted using a stand-alone cage/plate system. Postoperatively, the severity of spondylolisthesis diminished, with resolution of symptoms. However, the patient returned 2 months later with both leg weakness and back pain. Plain radiographs and CT indicated device failure due to anterior fracture of the L-4 vertebral body, and the spondylolisthesis had recurred. At this point, bilateral facetectomies were performed, with reduction/fixation of L3-4 by pedicle screws. Again, degenerative spondylolisthesis improved postsurgically and symptoms eased, with eventual healing of the vertebral body fracture. This report documents a rare instance of L-4 vertebral body fracture following use of a stand-alone device for ALIF at L3-4, likely as a consequence of angular instability in degenerative spondylolisthesis. Under such conditions, additional pedicle screw fixation is advised.

  5. A New Approach for Optimal Sizing of Standalone Photovoltaic Systems

    Directory of Open Access Journals (Sweden)

    Tamer Khatib

    2012-01-01

    Full Text Available This paper presents a new method for determining the optimal sizing of standalone photovoltaic (PV system in terms of optimal sizing of PV array and battery storage. A standalone PV system energy flow is first analysed, and the MATLAB fitting tool is used to fit the resultant sizing curves in order to derive general formulas for optimal sizing of PV array and battery. In deriving the formulas for optimal sizing of PV array and battery, the data considered are based on five sites in Malaysia, which are Kuala Lumpur, Johor Bharu, Ipoh, Kuching, and Alor Setar. Based on the results of the designed example for a PV system installed in Kuala Lumpur, the proposed method gives satisfactory optimal sizing results.

  6. Maintenance of a Drosophila melanogaster Population Cage.

    Science.gov (United States)

    Caravaca, Juan Manuel; Lei, Elissa P

    2016-03-15

    Large quantities of DNA, RNA, proteins and other cellular components are often required for biochemistry and molecular biology experiments. The short life cycle of Drosophila enables collection of large quantities of material from embryos, larvae, pupae and adult flies, in a synchronized way, at a low economic cost. A major strategy for propagating large numbers of flies is the use of a fly population cage. This useful and common tool in the Drososphila community is an efficient way to regularly produce milligrams to tens of grams of embryos, depending on uniformity of developmental stage desired. While a population cage can be time consuming to set up, maintaining a cage over months takes much less time and enables rapid collection of biological material in a short period. This paper describes a detailed and flexible protocol for the maintenance of a Drosophila melanogaster population cage, starting with 1.5 g of harvested material from the previous cycle.

  7. 49 CFR 1111.8 - Procedural schedule in stand-alone cost cases.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Procedural schedule in stand-alone cost cases... § 1111.8 Procedural schedule in stand-alone cost cases. (a) Procedural schedule. Absent a specific order by the Board, the following general procedural schedule will apply in stand-alone cost cases: Day 0...

  8. Compositions containing borane or carborane cage compounds and related applications

    Science.gov (United States)

    Bowen, III, Daniel E; Eastwood, Eric A

    2013-05-28

    Compositions comprising a polymer-containing matrix and a filler comprising a cage compound selected from borane cage compounds, carborane cage compounds, metal complexes thereof, residues thereof, mixtures thereof, and/or agglomerations thereof, where the cage compound is not covalently bound to the matrix polymer. Methods of making and applications for using such compositions are also disclosed.

  9. Stand-Alone Lateral Interbody Fusion for the Treatment of Low-Grade Degenerative Spondylolisthesis

    Directory of Open Access Journals (Sweden)

    Luis Marchi

    2012-01-01

    Full Text Available The purpose of this paper was to investigate the stand-alone lateral interbody fusion as a minimally invasive option for the treatment of low-grade degenerative spondylolisthesis with a minimum 24-month followup. Prospective nonrandomized observational single-center study. 52 consecutive patients (67.6±10 y/o; 73.1% female; 27.4±3.4 BMI with single-level grade I/II single-level degenerative spondylolisthesis without significant spine instability were included. Fusion procedures were performed as retroperitoneal lateral transpsoas interbody fusions without screw supplementation. The procedures were performed in average 73.2 minutes and with less than 50cc blood loss. VAS and Oswestry scores showed lasting improvements in clinical outcomes (60% and 54.5% change, resp.. The vertebral slippage was reduced in 90.4% of cases from mean values of 15.1% preoperatively to 7.4% at 6-week followup (P<0.001 and was maintained through 24 months (7.1%, P<0.001. Segmental lordosis (P<0.001 and disc height (P<0.001 were improved in postop evaluations. Cage subsidence occurred in 9/52 cases (17% and 7/52 cases (13% spine levels needed revision surgery. At the 24-month evaluation, solid fusion was observed in 86.5% of the levels treated. The minimally invasive lateral approach has been shown to be a safe and reproducible technique to treat low-grade degenerative spondylolisthesis.

  10. Structure and dynamics of empty cages in xenon clathrate hydrate.

    Science.gov (United States)

    Ikeda-Fukazawa, Tomoko; Yamaguchi, Yohei; Nagashima, Kazushige; Kawamura, Katsuyuki

    2008-12-14

    We performed molecular dynamics calculations of xenon clathrate hydrate to investigate the effects of empty cages on the structure and dynamics of the surrounding lattice. The distinct structure and dynamics of the empty cages, and cages including Xe, which coexist in the lattice, were analyzed. The results show that the ellipsoidal tetrakaidecahedral cage shrinks along the minor (100) axis and expands along the major (100) axis due to the absence of Xe from the cage, whereas the dodecahedral cage shrinks isotropically. These distortions of the empty cages cause a reduction in the lattice constant and an enhancement of the thermal vibrations of the surrounding lattice. The vibrational density of states shows that the hydrogen bonds consisting of the tetrakaidecahedral cage are strengthened by the absence of Xe, whereas those of the dodecahedral cage are weakened. These results show differing mechanisms of guest-host interaction for the two types of cages including Xe. Repulsion is the dominant guest-host interaction for the dodecahedral cage, as proposed by previous studies. For the tetrakaidecahedral cage, however, attractive interaction is dominant along the major (100) axis, whereas repulsive interaction is dominant along the minor (100) axis. The present results suggest that a small number of empty cages can affect not only the local structures but also the macroscopic properties of the crystal. It is concluded that the distortions of the empty cages are one of the important factors governing the density and phase equilibrium of clathrate hydrates.

  11. Radon Monitoring in Army Stand-Alone Housing Units

    Science.gov (United States)

    1990-04-01

    Y cm a cc 0000 0003 000 000 :: - -@-I.00 cmjinu mooc . 0J~CJ~ TTTT J !8 2 T WWWW WW.000 coo 0~~ 80 Im - v ;o e I3 ec ;: C -1,4 04. -c mco : - a c W" 1 .1...Chamber ....................... 25 V U I I I viI Final Report, April 1990 Radon Monitoring in Army Stand-alone Housing Units Summary Argonne National...and analysis. The quality control protocols appli- cable to detector analysis are contained in Chapter V of the procedures manual developed by Tech

  12. Future UK markets for stand-alone renewable energy systems

    International Nuclear Information System (INIS)

    Paish, O.

    1999-01-01

    A study to identify and quantify the market for stand-alone renewable energy supplies of power (photovoltaics, wind and micro-hydro electricity systems) was described. The study focused on small systems, generally less than a few kW installed capacity. It was suggested that in the UK, the emphasis on grid-connected renewable energy technologies (RETs) has blurred the fact that it is 'off-grid' renewable systems that can offer more immediate real commercial markets for the renewables business. With the likelihood of a significant increase in demand for renewables world wide over the next ten years, the UK needs to make a special effort to become involved

  13. Laboratory rodent welfare: thinking outside the cage.

    Science.gov (United States)

    Balcombe, Jonathan

    2010-01-01

    This commentary presents the case against housing rats and mice in laboratory cages; the commentary bases its case on their sentience, natural history, and the varied detriments of laboratory conditions. The commentary gives 5 arguments to support this position: (a) rats and mice have a high degree of sentience and can suffer, (b) laboratory environments cause suffering, (c) rats and mice in the wild have discrete behavioral needs, (d) rats and mice bred for many generations in the laboratory retain these needs, and (e) these needs are not met in laboratory cages.

  14. Minimally invasive lateral transpsoas interbody fusion using a stand-alone construct for the treatment of adjacent segment disease of the lumbar spine: review of the literature and report of three cases.

    Science.gov (United States)

    Palejwala, Sheri K; Sheen, Whitney A; Walter, Christina M; Dunn, Jack H; Baaj, Ali A

    2014-09-01

    We describe 3 patients who presented with radiographic signs and clinical symptoms of adjacent segment disease several years after undergoing L4-S1 posterior pedicle screw fusion. All patients underwent successful lateral lumbar interbody fusion (LLIF) at 1-2 levels above their previous constructs, using stand-alone cages, with complete resolution of radiculopathy and a significant improvement in low-back pain. In addition to a thorough analysis of these cases, we review the pertinent literature regarding treatment options for adjacent segment disease and the applications of the lateral lumbar interbody technique. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. High-throughput Transcriptome analysis, CAGE and beyond

    KAUST Repository

    Kodzius, Rimantas

    2008-11-25

    1. Current research - PhD work on discovery of new allergens - Postdoctoral work on Transcriptional Start Sites a) Tag based technologies allow higher throughput b) CAGE technology to define promoters c) CAGE data analysis to understand Transcription - Wo

  16. Pentagonal dodecahedron methane hydrate cage and methanol ...

    Indian Academy of Sciences (India)

    NBO analysis and red shift of vibrational frequency reveal that hydrogen bond formation between methanol and water molecules of 1CH4@512 cage is favourable subsequently after breaking its original hydrogen bonded network. Keywords. Density functional theory; natural bond orbital; red shift of vibrational frequency;.

  17. Design and analysis of roll cage

    Science.gov (United States)

    Angadi, Gurusangappa; Chetan, S.

    2018-04-01

    Wildlife fire fighting vehicles are used to extinguish fires in forests, in this process vehicles face falling objects like rocks, tree branches and other objects. Also due to uneven conditions of the terrain like cliff edges, uneven surfaces etc. makes the vehicle to roll over and these can cause injuries to both the driver and the operator. Roll over of a vehicle is a common incident which makes fatal injuries to the operator and also stands next to the crash accidents. In order to reduce the injury level and continuous roll over of the vehicle it is necessary to equip suitable roll cage according to standards of vehicle. In this present work roll cage for pump operator in wildfire fighting vehicle is designed and analysis is carried out in computer simulated environment when seating position of operator seated outside of the cabin. According to NFPA 1906 standards wildlife fire apparatus, Design and Test procedures that are carried out in Hyperworks maintaining SAE J1194.1983 standards. G load case, roof crush analysis and pendulum impact analysis tests are carried out on roll cage to ensure the saftey of design. These load cases are considerd to satisfy the situation faced in forest terrain. In these test procedures roll cage is analysed for stresses and deformation in various load cases. After recording results these are compared with standards mentioned in SAE J1194.1983.

  18. Computational study of retro Trp-cage

    Czech Academy of Sciences Publication Activity Database

    Vymětal, Jiří; Bathula, S. R.; Žídek, L.; Černý, Jiří; Sklenář, V.; Vondrášek, Jiří

    2012-01-01

    Roč. 12, č. 1 (2012), s. 54-55 ISSN 1210-8529. [10th Discussions in Structural Molecular Biology . 22.03.2012-24.03.2012, Nové Hrady] Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520701 Keywords : TRP-cage Subject RIV: CF - Physical ; Theoretical Chemistry

  19. Geomechanics of fracture caging in wellbores

    NARCIS (Netherlands)

    Weijermars, R.; Zhang, X.; Schultz-Ela, D.

    2013-01-01

    This study highlights the occurrence of so-called ‘fracture cages’ around underbalanced wellbores, where fractures cannot propagate outwards due to unfavourable principal stress orientations. The existence of such cages is demonstrated here by independent analytical and numerical methods. We explain

  20. Pentagonal dodecahedron methane hydrate cage and methanol ...

    Indian Academy of Sciences (India)

    Abstract. Density functional theory based studies have been performed to elucidate the role of methanol as an methane hydrate inhibitor. A methane hydrate pentagonal dodecahedron cage's geometry optimization, natural bond orbital (NBO) analysis, Mullikan charge determination, electrostatic potential evaluation and ...

  1. Porous Organic Cage Thin Films and Molecular-Sieving Membranes.

    Science.gov (United States)

    Song, Qilei; Jiang, Shan; Hasell, Tom; Liu, Ming; Sun, Shijing; Cheetham, Anthony K; Sivaniah, Easan; Cooper, Andrew I

    2016-04-06

    Porous organic cage molecules are fabricated into thin films and molecular-sieving membranes. Cage molecules are solution cast on various substrates to form amorphous thin films, with the structures tuned by tailoring the cage chemistry and processing conditions. For the first time, uniform and pinhole-free microporous cage thin films are formed and demonstrated as molecular-sieving membranes for selective gas separation. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Hydrogen Gas Production in a Stand-Alone Wind Farm

    Directory of Open Access Journals (Sweden)

    M. Naziry Kordkandy

    2017-04-01

    Full Text Available This paper is analyzing the operation of a stand-alone wind farm with variable speed turbines, permanent magnet synchronous generators (PMSG and a system for converting wind energy during wind speed variations. On this paper, the design and modeling of a wind system which uses PMSG’s to provide the required power of a hydrogen gas electrolyzer system, is discussed. This wind farm consists of three wind turbines, boost DC-DC converters, diode full bridge rectifiers, permanent magnet synchronous generators, MPPT control and a hydrogen gas electrolyzer system. The MPPT controller based on fuzzy logic is designed to adjust the duty ratio of the boost DC-DC converters to absorb maximum power. The proposed fuzzy logic controller assimilates, with (PSF MPPT algorithm which generally used to absorb maximum power from paralleled wind turbines and stores it in form of hydrogen gas. The system is modeled and its behavior is studied using the MATLAB software.

  3. DOE and AID stand-alone photovoltaic activities

    Science.gov (United States)

    Bifano, W. J.; Ratajczak, A. F.

    The NASA Lewis Research Center (LeRC) is managing stand-alone photovoltaic (PV) system activities sponsored by the U.S. Department of Energy (DOE) and the U.S. Agency for International Development (AID). The DOE project includes village PV power demonstration projects in Gabon (four sites) and the Marshall Islands, PV-powered medical refrigerators in six countries, PV system microprocessor control development activities and PV-hybrid system assessments. The AID project includes a large village system in Tunisia, a water pumping/grain grinding project in Upper Volta, five medical clinics in four countries, PV-powered remote earth station application. These PV activities and summarizes significant findings to data are reviewed.

  4. Design and control of a standalone PV water pumping system

    Directory of Open Access Journals (Sweden)

    Essam E. Aboul Zahab

    2017-09-01

    Full Text Available Water resources are vital for satisfying human needs. However, almost one-fifth of the world’s population – about 1.2 billion people – live in areas where water is physically rare. One quarter of the global population also live in developing countries that face water shortages. This paper presents standalone PV water pumping system. Photovoltaic (PV is the main power source, and lead acid batteries are used as energy storage system, to supply a water pump driven by a BLDC motor. The proposed control strategy consists of three control units. The first unit is to control the speed and hysteresis current controller for BLDC motor. The maximum power point tracking (MPPT is the second control unit, and the battery charging/discharging system is controlled by the third controller. The simulation results show the effectiveness and the good efficiency of the proposed system.

  5. Coding considerations for standalone molecular dynamics simulations of atomistic structures

    Science.gov (United States)

    Ocaya, R. O.; Terblans, J. J.

    2017-10-01

    The laws of Newtonian mechanics allow ab-initio molecular dynamics to model and simulate particle trajectories in material science by defining a differentiable potential function. This paper discusses some considerations for the coding of ab-initio programs for simulation on a standalone computer and illustrates the approach by C language codes in the context of embedded metallic atoms in the face-centred cubic structure. The algorithms use velocity-time integration to determine particle parameter evolution for up to several thousands of particles in a thermodynamical ensemble. Such functions are reusable and can be placed in a redistributable header library file. While there are both commercial and free packages available, their heuristic nature prevents dissection. In addition, developing own codes has the obvious advantage of teaching techniques applicable to new problems.

  6. Integral type small PWR with stand-alone safety

    International Nuclear Information System (INIS)

    Makihara, Yoshiaki

    2001-01-01

    A feasibility study is achieved on an integral type small PWR with stand-alone safety. It is designed to have the following features. (1) The coolant does not leak out at any accidental condition. (2) The fuel failure does never occur while it is supposed on the large scale PWR at the design base accident. (3) At any accidental condition the safety is secured without any support from the outside (stand-alone safety secure). (4) It has self-regulating characteristics and easy controllability. The above features can be satisfied by integrate the steam generator and CRDM in the reactor vessel while the pipe line break has to be considered on the conventional PWR. Several counter measures are planned to satisfy the above features. The economy feature is also attained by several simplifications such as (1) elimination of main coolant piping and pressurizer by the integration of primary cooling system and self-pressurizing, (2) elimination of RCP by application of natural circulating system, (3) elimination of ECCS and accumulator by application of static safety system, (4) large scale volume reduction of the container vessel by application of integrated primary cooling system, (5) elimination of boric acid treatment by deletion of chemical shim. The long operation period such as 10 years can be attained by the application of Gd fuel in one batch refueling. The construction period can be shortened by the standardizing the design and the introduction of modular component system. Furthermore the applicability of the reduced modulation core is also considered. (K. Tsuchihashi)

  7. A fully integrated standalone portable cavity ringdown breath acetone analyzer.

    Science.gov (United States)

    Sun, Meixiu; Jiang, Chenyu; Gong, Zhiyong; Zhao, Xiaomeng; Chen, Zhuying; Wang, Zhennan; Kang, Meiling; Li, Yingxin; Wang, Chuji

    2015-09-01

    Breath analysis is a promising new technique for nonintrusive disease diagnosis and metabolic status monitoring. One challenging issue in using a breath biomarker for potential particular disease screening is to find a quantitative relationship between the concentration of the breath biomarker and clinical diagnostic parameters of the specific disease. In order to address this issue, we need a new instrument that is capable of conducting real-time, online breath analysis with high data throughput, so that a large scale of clinical test (more subjects) can be achieved in a short period of time. In this work, we report a fully integrated, standalone, portable analyzer based on the cavity ringdown spectroscopy technique for near-real time, online breath acetone measurements. The performance of the portable analyzer in measurements of breath acetone was interrogated and validated by using the certificated gas chromatography-mass spectrometry. The results show that this new analyzer is useful for reliable online (online introduction of a breath sample without pre-treatment) breath acetone analysis with high sensitivity (57 ppb) and high data throughput (one data per second). Subsequently, the validated breath analyzer was employed for acetone measurements in 119 human subjects under various situations. The instrument design, packaging, specifications, and future improvements were also described. From an optical ringdown cavity operated by the lab-set electronics reported previously to this fully integrated standalone new instrument, we have enabled a new scientific tool suited for large scales of breath acetone analysis and created an instrument platform that can even be adopted for study of other breath biomarkers by using different lasers and ringdown mirrors covering corresponding spectral fingerprints.

  8. A fully integrated standalone portable cavity ringdown breath acetone analyzer

    Science.gov (United States)

    Sun, Meixiu; Jiang, Chenyu; Gong, Zhiyong; Zhao, Xiaomeng; Chen, Zhuying; Wang, Zhennan; Kang, Meiling; Li, Yingxin; Wang, Chuji

    2015-09-01

    Breath analysis is a promising new technique for nonintrusive disease diagnosis and metabolic status monitoring. One challenging issue in using a breath biomarker for potential particular disease screening is to find a quantitative relationship between the concentration of the breath biomarker and clinical diagnostic parameters of the specific disease. In order to address this issue, we need a new instrument that is capable of conducting real-time, online breath analysis with high data throughput, so that a large scale of clinical test (more subjects) can be achieved in a short period of time. In this work, we report a fully integrated, standalone, portable analyzer based on the cavity ringdown spectroscopy technique for near-real time, online breath acetone measurements. The performance of the portable analyzer in measurements of breath acetone was interrogated and validated by using the certificated gas chromatography-mass spectrometry. The results show that this new analyzer is useful for reliable online (online introduction of a breath sample without pre-treatment) breath acetone analysis with high sensitivity (57 ppb) and high data throughput (one data per second). Subsequently, the validated breath analyzer was employed for acetone measurements in 119 human subjects under various situations. The instrument design, packaging, specifications, and future improvements were also described. From an optical ringdown cavity operated by the lab-set electronics reported previously to this fully integrated standalone new instrument, we have enabled a new scientific tool suited for large scales of breath acetone analysis and created an instrument platform that can even be adopted for study of other breath biomarkers by using different lasers and ringdown mirrors covering corresponding spectral fingerprints.

  9. Cage subsidence after anterior cervical discectomy and fusion using a cage alone or combined with anterior plate fixation.

    Science.gov (United States)

    Pinder, E M; Sharp, D J

    2016-04-01

    To compare the extent of cage subsidence after anterior cervical discectomy and fusion (ACDF) using a cage alone or combined with anterior plate fixation, and to assess the effect of end plate removal on cage subsidence. Records of 23 men and 13 women aged 32 to 82 (mean, 54) years who underwent ACDF for 61 levels using the Solis cage alone (n=46) or combined with anterior plate fixation (n=15) were reviewed. The extent of cage subsidence was determined by comparing immediately postoperative (within one week) with final follow-up radiographs. Cage subsidence was defined as the sum subsidence of the superior and inferior part of the cage into the vertebral body. Mild and major cage subsidence was defined as ≤2 mm and >2 mm, respectively. Patients who underwent ACDF using a cage alone or combined with anterior plate fixation were comparable in terms of age, gender, follow-up duration, and number of levels decompressed. Cage subsidence occurred in 33 (54%) of the 61 levels decompressed. In the cage alone group, the extent of cage subsidence was greater (1.68 vs. 0.57 mm, p=0.039) and the rate of major cage subsidence was higher (28% vs. 7%, p=0.08). The inferior part of the cage was more vulnerable to subsidence compared with the superior part (median subsidence: 3.0 vs. 1.4 mm, psubsidence occurred more often when the end plate was removed rather than preserved (58% vs. 18%, psubsidence was greater after ACDF with cage alone. Cage subsidence occurred more often when the end plate was removed. Additional anterior plate fixation is recommended when the end plate is removed.

  10. Integrated Three-Port DC-DC Converter for Photovoltaic (PV) Battery Stand-alone Systems

    DEFF Research Database (Denmark)

    Ouyang, Ziwei; Andersen, Michael A. E.

    2016-01-01

    Several power sources such as PV solar arrays and battery are often used to manage the power flow for a photovoltaic (PV) based stand-alone power system due to the fluctuation nature of solar energy resource, and deliver a continuous power to the users in an appropriate form. Traditionally, three...... for PV and battery stand-alone system....

  11. Validation of the standalone implementation of the dynamic wake meandering model for power production

    DEFF Research Database (Denmark)

    Keck, Rolf-Erik Henrik Jussi

    2015-01-01

    This paper presents validation for using the standalone implementation of the dynamic wake meandering (DWM) model to conduct numerical simulations of power production of rows of wind turbines. The standalone DWM model is an alternative formulation of the conventional DWM model that does not require...... be seen as an alternative for simulating the power production of a wind farm. The main advantage of the standalone DWM model is the ability to capture the key physics for wake dynamics such as the turbine specific induction, the build‐up of wake turbulence and wake deficit in the wind farm, and the effect...... information exchange with an aeroelastic code. As a consequence, the standalone DWM model has significantly shorter computational times and lower demands on the user environment. The drawback of the standalone DWM model is that it does not have the capability to predict turbine loads. Instead, it should...

  12. Simulation of potential standalone liquid desiccant cooling cycles

    International Nuclear Information System (INIS)

    Das, Rajat Subhra; Jain, Sanjeev

    2015-01-01

    LDCS (Liquid desiccant cooling systems), capable of achieving dehumidification and cooling with low-grade heat input, can be effectively used for treating fresh air in hot and humid regions. These can also be operated using non-concentrating solar collectors. The present study is concerned with the evaluation of various potential liquid desiccant cycles for tropical climatic conditions. Six potential standalone liquid desiccant cycles are identified and analyzed to select the best configuration for achieving thermal comfort. A computer simulation model is developed in EES (Equation Solver) software platform to evaluate the performance of all the cycles at various operating conditions. Aqueous solution of LiCl (lithium chloride) is used as desiccant. Mass and energy balance equations of all the components along with their effectiveness and LiCl property correlation equations are solved simultaneously for given ambient conditions. As the desiccant circuit is a closed loop, no assumptions are made about its concentration and temperature in the algorithm. Supply air conditions, cooling capacity, COP (capacity and coefficient of performance) and CR (circulation rate) per unit cooling capacity and hot water temperature requirement are used as a measure for analyzing the performance of the different cycles. The effect of hot water temperature on the performance of the cycles is evaluated at ARI conditions. The performances of the cycles are also evaluated for cities selected from each of the climatic zone of India that represent typical tropical climates. Although all the cycles are feasible at ARI and hot and dry conditions, only two cycles can achieve the selected indoor conditions in the peak humid conditions. The results would be useful for selecting suitable liquid desiccant cycle for a given climate. - Highlights: • Six potential standalone liquid desiccant cycles identified and analyzed to select best configuration. • A computer simulation model is developed in

  13. The Stand-alone Heliostat; El Heliostato Autonomo

    Energy Technology Data Exchange (ETDEWEB)

    Garcia Navajas, G.; Egea Gea, A. [Ciemat. Madrid (Spain)

    2000-07-01

    The first Autonomous Heliostat has been developed by CIEMAT at PSA facilities in Almeria. This heliostat is an innovative approach to reducing the civil engineering work costs in heliostat fields of central tower plants. Channels, cables and other electric elements have been eliminated in the new heliostat. Thus, one 70-m''2, classical T glass/metal heliostat has been adapted to include all the new stand-alone concept components. A PV system is able to drive two sun-tracking DC motors between 5 and 24 Vdc, 0 and 15A. The heliostat communicates with the control room 400-m away by using a radio-modern working at 9600 baud. An anemometer, a wind switcher, light and ambient temperature sensors have been installed on the heliostat for self-protection decision-making. A PV panel integrated into the heliostat reflecting surface, eliminates cabling and other elements required for a conventional power supply. Communication lines between master control and local control have been replaced by radio-modern. Testing has validated the technical feasibility of the prototype and quantified the real consumption and efficiencies of new elements. The extra costs produced by the autonomous concepts are compared with the cost of civil work in conventional heliostat field. (Author) 8 refs.

  14. A control strategy for PV stand-alone applications

    Science.gov (United States)

    Slouma, S.; Baccar, H.

    2015-04-01

    This paper proposes a stand-alone photovoltaic (PV) system study in domestic applications. Because of the decrease in power of photovoltaic module as a consequence of changes in solar radiation and temperature which affect the photovoltaic module performance, the design and control of DC-DC buck converter was proposed for providing power to the load from a photovoltaic source.In fact, the control of this converter is carried out with integrated MPPT (Maximum Power Point Tracking) algorithm which ensures a maximum energy generated by the PV arrays. Moreover, the output stage is composed by a battery energy storage system, dc-ac inverter, LCL filter which enables higher efficiency, low distortion ac waveforms and low leakage currents. The control strategy adopted is cascade control composed by two regulation loops.Simulations performed with PSIM software were able to validate the control system.The realization and testing of the photovoltaic system were achieved in the Photovoltaic laboratory of the Centre for Research and Energy Technologies at the Technopark Borj Cedria. Experimental results verify the effeciency of the proposed system.

  15. Foldit Standalone: a video game-derived protein structure manipulation interface using Rosetta.

    Science.gov (United States)

    Kleffner, Robert; Flatten, Jeff; Leaver-Fay, Andrew; Baker, David; Siegel, Justin B; Khatib, Firas; Cooper, Seth

    2017-09-01

    Foldit Standalone is an interactive graphical interface to the Rosetta molecular modeling package. In contrast to most command-line or batch interactions with Rosetta, Foldit Standalone is designed to allow easy, real-time, direct manipulation of protein structures, while also giving access to the extensive power of Rosetta computations. Derived from the user interface of the scientific discovery game Foldit (itself based on Rosetta), Foldit Standalone has added more advanced features and removed the competitive game elements. Foldit Standalone was built from the ground up with a custom rendering and event engine, configurable visualizations and interactions driven by Rosetta. Foldit Standalone contains, among other features: electron density and contact map visualizations, multiple sequence alignment tools for template-based modeling, rigid body transformation controls, RosettaScripts support and an embedded Lua interpreter. Foldit Standalone is available for download at https://fold.it/standalone , under the Rosetta license, which is free for academic and non-profit users. It is implemented in cross-platform C ++ and binary executables are available for Windows, macOS and Linux. scooper@ccs.neu.edu. © The Author(s) 2017. Published by Oxford University Press.

  16. Seismic stability of a standalone glove box structure

    International Nuclear Information System (INIS)

    Saraswat, A.; Reddy, G.R.; Ghosh, S.; Ghosh, A.K.; Kumar, Arun

    2014-01-01

    Highlights: • Glove box is a leak tight, safety related structure used for handling radiotoxic materials. • To study the seismic performance of a freestanding glove box, extensive shake table testing has been carried out. • Glove box maintained structural integrity and leak tightness up to design basis earthquake loading. • Detailed three-dimensional finite element model of the structure is developed and analyzed by using direct time integration methods. • Simplified numerical method is proposed and successfully applied, to quickly estimate sliding displacement and determine upper bounds for it. - Abstract: In a nuclear fuel cycle facility, radiotoxic materials are being handled in freestanding leak tight enclosures called glove boxes (GBs). These glove boxes act as a primary confinement for the radiotoxic materials. Glove boxes are designed as per codal requirements for class I component. They are designed to withstand extreme level of earthquake loading with a return period of 10,000 years. To evaluate seismic performance of the glove box, there is a need to check the stability (sliding and overturning), structural integrity (stresses and strains) and leak tightness under earthquake loading. Extensive shake table experiments were conducted on a single standalone glove box. Actual laboratory conditions were simulated during testing to check the response. After extensive shake table testing, glove box structure was also analyzed using finite element (FE) software. Detailed three-dimensional model of glove box structure was developed and analyzed using nonlinear time history method. It was observed that finite element methods could be utilized to accurately predict dynamic response of glove box structure. This paper discusses the details and results of shake table testing and methodology used for modelling and analysing freestanding glove box structure under seismic loading. In addition, simplified numerical procedure, developed using energy conservation

  17. Seismic stability of a standalone glove box structure

    Energy Technology Data Exchange (ETDEWEB)

    Saraswat, A., E-mail: anupams@barc.gov.in [Bhabha Atomic Research Centre, Mumbai (India); Reddy, G.R. [Bhabha Atomic Research Centre, Mumbai (India); Ghosh, S. [Indian Institute of Technology Bombay, Mumbai (India); Ghosh, A.K.; Kumar, Arun [Bhabha Atomic Research Centre, Mumbai (India)

    2014-09-15

    Highlights: • Glove box is a leak tight, safety related structure used for handling radiotoxic materials. • To study the seismic performance of a freestanding glove box, extensive shake table testing has been carried out. • Glove box maintained structural integrity and leak tightness up to design basis earthquake loading. • Detailed three-dimensional finite element model of the structure is developed and analyzed by using direct time integration methods. • Simplified numerical method is proposed and successfully applied, to quickly estimate sliding displacement and determine upper bounds for it. - Abstract: In a nuclear fuel cycle facility, radiotoxic materials are being handled in freestanding leak tight enclosures called glove boxes (GBs). These glove boxes act as a primary confinement for the radiotoxic materials. Glove boxes are designed as per codal requirements for class I component. They are designed to withstand extreme level of earthquake loading with a return period of 10,000 years. To evaluate seismic performance of the glove box, there is a need to check the stability (sliding and overturning), structural integrity (stresses and strains) and leak tightness under earthquake loading. Extensive shake table experiments were conducted on a single standalone glove box. Actual laboratory conditions were simulated during testing to check the response. After extensive shake table testing, glove box structure was also analyzed using finite element (FE) software. Detailed three-dimensional model of glove box structure was developed and analyzed using nonlinear time history method. It was observed that finite element methods could be utilized to accurately predict dynamic response of glove box structure. This paper discusses the details and results of shake table testing and methodology used for modelling and analysing freestanding glove box structure under seismic loading. In addition, simplified numerical procedure, developed using energy conservation

  18. Effects of cage density on behavior in young adult mice.

    Science.gov (United States)

    Davidson, Lauren P; Chedester, Alan L; Cole, Marlene N

    2007-08-01

    Optimal housing conditions for mice can be achieved by minimizing environmental variables, such as those that may contribute to anxiety-like behavior. This study evaluated the effects of cage size on juvenile mice through assessment of differences in weaning weight, locomotor skills, and anxiety-like behavior. Eighteen pairs of male and pregnant female Swiss-Webster (Cr:SW) mice were housed in 3 different caging scenarios, providing 429, 505, or 729 cm2 of space. Litters were standardized to 10 pups per litter in each cage. Mice reared in each caging scenario were assessed with the open-field, light-dark exploration, and elevated plus-maze tests. No differences in weaning weight were noted. Mice reared in the 505- and 729-cm2 cages explored a significantly larger area of the open-field arena than did those in the 429-cm2 cages. Those reared in the 505-cm2 cages spent more time in the center of the open field than did those in the 729-cm2 cages, suggesting that anxiety-like behavior may be increased in the animals housed in the larger cages. This study did not establish a consistent link between decreased floor space and increased anxiety-like behavior; neither does there appear to be a consistent effect of available floor area on the development of locomotor skills on mouse pups.

  19. Precise site-selective termination of DNA replication by caging the 3-position of thymidine and its application to polymerase chain reaction.

    Science.gov (United States)

    Kuzuya, Akinori; Okada, Fuminori; Komiyama, Makoto

    2009-10-21

    A new caged thymidine, 3-N-(2-(2-nitrophenyl)propyloxymethyl)thymidine (T(NPPOM)) was synthesized and used as a site-selective terminator of DNA-polymerase reaction in light-assisted cohesive-ending PCR (LACE-PCR), which directly gives sticky-ended PCR products after brief UVA irradiation. Primer-extension experiments using a template involving T(NPPOM) have shown that this caged nucleotide efficiently and site-selectively blocks reactions of a variety of polymerases commonly used in PCR. Misincorporation of nucleobases, observed with the use of other previously reported caged thymidines, scarcely occurred. It has turned out that a slight structural difference of caging groups can significantly improve the termination yield of polymerase reactions. A LACE-PCR product coding GFP gene was prepared by using primers containing T(NPPOM) and was ligated with a vector fragment prepared using restriction enzymes. The resulting recombinant vector successfully transformed E. coli.

  20. Preinjector for Linac 1, Faraday cage

    CERN Document Server

    1974-01-01

    The 50 MeV Linac 1 started up in 1958 as injector to the 26 GeV PS, with a 520 kV Cockcroft-Walton generator as its preinjector, housed in a vast Faraday cage, visible here. When the Cockcroft-Walton broke down in 1973, it was replaced by a much smaller SAMES generator, of the kind used for electrostatic separators. From 1980 on, Linac 2 took over as injector for the 800 MeV Booster, and Linac 1 continued as injector for LEAR. In 1984, the electrostatic preinjector (i.e. the Faraday cage with its contents, SAMES generator and all) was replaced by a 520 keV RFQ. At the lower left corner we see the HV connectors to the SAMES generator, at the right edge part of the opened electronics-platform. Jean-Luc Vallet sees to it that all parts are properly grounded. See also 7403073X, 7403074X, 7403081X, 7403083X.

  1. Bulletproof Love : Luke Cage (2016 and Religion

    Directory of Open Access Journals (Sweden)

    Derry, Ken

    2017-05-01

    Full Text Available There are many ways to think about religion and popular culture. One method is to ask where and when we see what might be commonly understood as “religious tradition(s” explicitly on display. Another is to think about superhero narratives themselves as “religious”, using this term as a conceptual tool for categorizing and thereby better understanding particular dimensions of human experience. This article takes a variety of approaches to understanding religion in relation to the recent television series LUKE CAGE (Netflix, US 2016. These approaches take their hermeneutical cues from a range of disciplines, including studies of the Bible; Hip Hop; gender; Black Theology; African American religion; and philosophy. The results of this analysis highlight the polysemic nature of popular culture in general, and of superhero stories in particular. Like religious traditions themselves, the show is complex and contradictory: it is both progressive and reactionary; emphasizes community and valorizes an individual; critiques and endorses Christianity; subverts and promotes violence. Depending on the questions asked, LUKE CAGE (2016 provides a range of very different answers.

  2. Modeling & power management of standalone PV-Wind Hybrid energy system for remote location

    Science.gov (United States)

    Shawon, M. J. A.

    This thesis mainly focuses on a novel design of a standalone PV-Wind hybrid energy system for remote locations where grid extension is not feasible or is expensive. The Hybrid PV-Wind standalone energy system shows higher reliability compared to Wind or PV standalone systems as wind and solar are complementary. A Matlab/Simulink model of an integrated standalone PV-Wind hybrid system using a battery for storage and backup protection is presented. The individual component of the system is discussed and modeled. A novel and unique control strategy is designed and simulated to control the power flow of the system while maintaining the battery charging and discharging limit. In addition, different converter design and maximum power point tracking control are applied to ensure efficient and reliable power supply under various atmospheric and loading conditions.

  3. Computed tomography measurement of rib cage morphometry in emphysema.

    Directory of Open Access Journals (Sweden)

    Nicola Sverzellati

    Full Text Available BACKGROUND: Factors determining the shape of the human rib cage are not completely understood. We aimed to quantify the contribution of anthropometric and COPD-related changes to rib cage variability in adult cigarette smokers. METHODS: Rib cage diameters and areas (calculated from the inner surface of the rib cage in 816 smokers with or without COPD, were evaluated at three anatomical levels using computed tomography (CT. CTs were analyzed with software, which allows quantification of total emphysema (emphysema%. The relationship between rib cage measurements and anthropometric factors, lung function indices, and %emphysema were tested using linear regression models. RESULTS: A model that included gender, age, BMI, emphysema%, forced expiratory volume in one second (FEV1%, and forced vital capacity (FVC% fit best with the rib cage measurements (R(2 = 64% for the rib cage area variation at the lower anatomical level. Gender had the biggest impact on rib cage diameter and area (105.3 cm(2; 95% CI: 111.7 to 98.8 for male lower area. Emphysema% was responsible for an increase in size of upper and middle CT areas (up to 5.4 cm(2; 95% CI: 3.0 to 7.8 for an emphysema increase of 5%. Lower rib cage areas decreased as FVC% decreased (5.1 cm(2; 95% CI: 2.5 to 7.6 for 10 percentage points of FVC variation. CONCLUSIONS: This study demonstrates that simple CT measurements can predict rib cage morphometric variability and also highlight relationships between rib cage morphometry and emphysema.

  4. A review on recent size optimization methodologies for standalone solar and wind hybrid renewable energy system

    International Nuclear Information System (INIS)

    Al-falahi, Monaaf D.A.; Jayasinghe, S.D.G.; Enshaei, H.

    2017-01-01

    Highlights: • Possible combinations and configurations for standalone PV-WT HES were discussed. • Most recently used assessment parameters for standalone PV-WT HES were explained. • Optimization algorithms and software tools were comprehensively reviewed. • The recent trend of using hybrid algorithms over single algorithms was discussed. • Optimization algorithms for sizing standalone PV-WT HES were critically compared. - Abstract: Electricity demand in remote and island areas are generally supplied by diesel or other fossil fuel based generation systems. Nevertheless, due to the increasing cost and harmful emissions of fossil fuels there is a growing trend to use standalone hybrid renewable energy systems (HRESs). Due to the complementary characteristics, matured technologies and availability in most areas, hybrid systems with solar and wind energy have become the popular choice in such applications. However, the intermittency and high net present cost are the challenges associated with solar and wind energy systems. In this context, optimal sizing is a key factor to attain a reliable supply at a low cost through these standalone systems. Therefore, there has been a growing interest to develop algorithms for size optimization in standalone HRESs. The optimal sizing methodologies reported so far can be broadly categorized as classical algorithms, modern techniques and software tools. Modern techniques, based on single artificial intelligence (AI) algorithms, are becoming more popular than classical algorithms owing to their capabilities in solving complex optimization problems. Moreover, in recent years, there has been a clear trend to use hybrid algorithms over single algorithms mainly due to their ability to provide more promising optimization results. This paper aims to present a comprehensive review on recent developments in size optimization methodologies, as well as a critical comparison of single algorithms, hybrid algorithms, and software tools

  5. First Results from the ALICE TPC Field Cage Prototype

    CERN Document Server

    Bächler, J; CERN. Geneva; Garabatos, C; Goret, B; Hoch, M; Klempt, W; Lagrue, X; Lenoir, P; Lesenechal, Y; Mast, M; Meyer, T C; Raynaud, J; Renfordt, R E; Schäfer, E; Sharma, A; Vranic, D

    2000-01-01

    Abstract This note summarizes the first phase in a series of tests with the ALICE TPC field cage prototype. We will demonstrate that the chosen design of the field cage and the layout of the potential degrader are able to satisfy our specific demands on static HV stability of the ALICE TPC at the LHC Heavy-Ion- Collider.

  6. Polymers containing borane or carborane cage compounds and related applications

    Science.gov (United States)

    Bowen, III, Daniel E.; Eastwood, Eric A [Raymore, MO

    2012-06-05

    Polymers comprising residues of borane and/or carborane cage compound monomers having at least one polyalkoxy silyl substituent. Such polymers can further comprise one or more reactive matrices and/or co-monomers covalently bound with the cage compound monomer residues. Methods of making and applications for using such polymers are also disclosed.

  7. 48 CFR 204.7202-1 - CAGE codes.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contractor Identification 204.7202-1 CAGE codes. (a... CD ROM that contains the H-4/H-8 CAGE master file issued by DLIS (Their address is: Customer Service... assignments to DLIS Customer Service: toll-free (888) 227-2423 or (888) 352-9333; DSN 932-4725; or commercial...

  8. Comparative architecture of octahedral protein cages. I. Indexed enclosing forms

    Science.gov (United States)

    Janner, A.

    2008-07-01

    The architecture of four protein cages (bacterio ferritin, human mitochondrial ferritin, sulfur oxygenase reductase and small heat-shock protein) are compared top-to-bottom, starting from polyhedra with vertices at cubic lattice points enclosing the cage down to indexed polyhedral forms of single monomers.

  9. Influence of Clarias gariepinus (Teugels) cage cultures on water ...

    African Journals Online (AJOL)

    Water quality, periphyton and phytoplankton growing as a function Clarias gariepinus (Burchell, 1822) cage cultures have rarely been investigated. Physical and chemical factors associated with cage culture of Clarias gariepinus in relation to phytoplankton and periphyton were examined fortnightly from May to June 2009 ...

  10. Abnormal Behavior in Relation to Cage Size in Rhesus Monkeys

    Science.gov (United States)

    Paulk, H. H.; And Others

    1977-01-01

    Examines the effects of cage size on stereotyped and normal locomotion and on other abnormal behaviors in singly caged animals, whether observed abnormal behaviors tend to co-occur, and if the development of an abnormal behavior repertoire leads to reduction in the number of normal behavior categories. (Author/RK)

  11. Teaching in the Institutional Cage: Metaphor and Collateral Oppression

    Science.gov (United States)

    Noël Smith, Becky L.

    2014-01-01

    This analysis is a philosophical exploration of Marilyn Frye's metaphor of the cage and Patricia Hill Collins' theory of intersecting oppressions. It argues that social structures and forms of oppressive knowledge make up the individual wires on each person's cage and that these work to confine individuals, particularly those in the…

  12. Generation of Multicomponent Molecular Cages using Simultaneous Dynamic Covalent Reactions.

    Science.gov (United States)

    Drożdż, Wojciech; Bouillon, Camille; Kotras, Clément; Richeter, Sébastien; Barboiu, Mihail; Clément, Sébastien; Stefankiewicz, Artur R; Ulrich, Sébastien

    2017-12-19

    Cage compounds are very attractive structures for a wide range of applications and there is ongoing interest in finding effective ways to access such kinds of complex structures, particularly those possessing dynamic adaptive features. Here we report the accessible synthesis of new type of organic cage architectures, possessing two different dynamic bonds within one structure: hydrazones and disulfides. Implementation of three distinct functional groups (thiols, aldehydes and hydrazides) in the structure of two simple building blocks resulted in their spontaneous and selective self-assembly into aromatic cage-type architectures. These organic cages contain up to ten components linked together by twelve reversible covalent bonds. The advantage provided by the presented approach is that these cage structures can adaptively self-sort from a complex virtual mixture of polymers or macrocycles and that dynamic covalent chemistry enables their deliberate disassembly through controlled component exchange. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Photoactivatable Caged Prodrugs of VEGFR-2 Kinase Inhibitors

    Directory of Open Access Journals (Sweden)

    Boris Pinchuk

    2016-04-01

    Full Text Available In this study, we report on the design, synthesis, photokinetic properties and in vitro evaluation of photoactivatable caged prodrugs for the receptor tyrosine kinase VEGFR-2. Highly potent VEGFR-2 inhibitors 1 and 3 were caged by introduction of a photoremovable protecting group (PPG to yield the caged prodrugs 4 and 5. As expected, enzymatic and cellular proliferation assays showed dramatically diminished efficacy of caged prodrugs in vitro. Upon ultraviolet (UV irradiation of the prodrugs original inhibitory activity was completely restored and even distinctly reinforced, as was the case for the prodrug 4. The presented results are a further evidence for caging technique being an interesting approach in the protein kinase field. It could enable spatial and temporal control for the inhibition of VEGFR-2. The described photoactivatable prodrugs might be highly useful as biological probes for studying the VEGFR-2 signal transduction.

  14. A Simple, Inexpensive Metabolism Cage for Small Mammals **

    Science.gov (United States)

    Pfeiffer, C. J.; Gass, G. H.

    1963-01-01

    By utilizing ordinary laboratory equipment and a spherical feces-urine separator, a simple, inexpensive metabolism cage for small mammals can be constructed. A hardware cloth animal cage over a cylindrical battery jar containing a spherical feces-urine separator affords the following advantages not commonly found in commercial metabolism cages: 1) complete separation of feces and urine through minimal contact, 2) minimal evaporation of urine due to proximity of storage vessel and lack of exogenous air currents, and 3) extremely low cost of less than five dollars. The metabolism cage is designed to allow measurement of fluid intake, and to separate and collect feces and urine for numerous qualitative and quantitative determinations. In addition, the metabolism cage permits observation of the animal, feces, and urine at all times, is readily cleaned or sterilized, and is easily fashioned from common laboratory equipment. ImagesFIG. 1. PMID:17649428

  15. Entropic cages for trapping DNA near a nanopore

    Science.gov (United States)

    Liu, Xu; Skanata, Mirna Mihovilovic; Stein, Derek

    2015-02-01

    Nanopores can probe the structure of biopolymers in solution; however, diffusion makes it difficult to study the same molecule for extended periods. Here we report devices that entropically trap single DNA molecules in a 6.2-femtolitre cage near a solid-state nanopore. We electrophoretically inject DNA molecules into the cage through the nanopore, pause for preset times and then drive the DNA back out through the nanopore. The saturating recapture time and high recapture probability after long pauses, their agreement with a convection-diffusion model and the observation of trapped DNA under fluorescence microscopy all confirm that the cage stably traps DNA. Meanwhile, the cages have 200 nm openings that make them permeable to small molecules, like the restriction endonuclease we use to sequence-specifically cut trapped DNA into fragments whose number and sizes are analysed upon exiting through the nanopore. Entropic cages thus serve as reactors for chemically modifying single DNA molecules.

  16. Nanocaged platforms: modification, drug delivery and nanotoxicity. Opening synthetic cages to release the tiger.

    Science.gov (United States)

    Karimi, Mahdi; Zangabad, Parham Sahandi; Mehdizadeh, Fatemeh; Malekzad, Hedieh; Ghasemi, Alireza; Bahrami, Sajad; Zare, Hossein; Moghoofei, Mohsen; Hekmatmanesh, Amin; Hamblin, Michael R

    2017-01-26

    Nanocages (NCs) have emerged as a new class of drug-carriers, with a wide range of possibilities in multi-modality medical treatments and theranostics. Nanocages can overcome such limitations as high toxicity caused by anti-cancer chemotherapy or by the nanocarrier itself, due to their unique characteristics. These properties consist of: (1) a high loading-capacity (spacious interior); (2) a porous structure (analogous to openings between the bars of the cage); (3) enabling smart release (a key to unlock the cage); and (4) a low likelihood of unfavorable immune responses (the outside of the cage is safe). In this review, we cover different classes of NC structures such as virus-like particles (VLPs), protein NCs, DNA NCs, supramolecular nanosystems, hybrid metal-organic NCs, gold NCs, carbon-based NCs and silica NCs. Moreover, NC-assisted drug delivery including modification methods, drug immobilization, active targeting, and stimulus-responsive release mechanisms are discussed, highlighting the advantages, disadvantages and challenges. Finally, translation of NCs into clinical applications, and an up-to-date assessment of the nanotoxicology considerations of NCs are presented.

  17. Cathodic Cage Plasma Nitriding: An Innovative Technique

    Directory of Open Access Journals (Sweden)

    R. R. M. de Sousa

    2012-01-01

    Full Text Available Cylindrical samples of AISI 1020, AISI 316, and AISI 420 steels, with different heights, were simultaneously treated by a new technique of ionic nitriding, entitled cathodic cage plasma nitriding (CCPN, in order to evaluate the efficiency of this technique to produce nitrided layers with better properties compared with those obtained using conventional ionic nitriding technique. This method is able to eliminate the edge effect in the samples, promoting a better uniformity of temperature, and consequently, a smaller variation of the thickness/height relation can be obtained. The compound layers were characterized by X-ray diffraction, optical microscopy, and microhardness test profile. The results were compared with the properties of samples obtained with the conventional nitriding, for the three steel types. It was verified that samples treated by CCPN process presented, at the same temperature, a better uniformity in the thickness and absence of the edge effect.

  18. Alejandra Pizarnik: the bird that was cage

    Directory of Open Access Journals (Sweden)

    Isabel Abellán Chuecos

    2014-07-01

    Full Text Available It is well known the relation –sometimes deceiving– that has been established by poets between literature and life. In the case of cursed poets, literature and life usually identify with each other, and talking about Alejandra Pizarnik, we could even establish this relation between literature and death, thus nothing is more daily than life. With this essay we try to identify the threads that converge and interweave the verses and the life, to be wandering and at the same time a prisoner, to have wings but stay in a cage, the confinement in a wandering reality. We will analyse the poetic individual and, at the same time, the construction of a character in life.

  19. Transcription regulatory networks analysis using CAGE

    KAUST Repository

    Tegnér, Jesper N.

    2009-10-01

    Mapping out cellular networks in general and transcriptional networks in particular has proved to be a bottle-neck hampering our understanding of biological processes. Integrative approaches fusing computational and experimental technologies for decoding transcriptional networks at a high level of resolution is therefore of uttermost importance. Yet, this is challenging since the control of gene expression in eukaryotes is a complex multi-level process influenced by several epigenetic factors and the fine interplay between regulatory proteins and the promoter structure governing the combinatorial regulation of gene expression. In this chapter we review how the CAGE data can be integrated with other measurements such as expression, physical interactions and computational prediction of regulatory motifs, which together can provide a genome-wide picture of eukaryotic transcriptional regulatory networks at a new level of resolution. © 2010 by Pan Stanford Publishing Pte. Ltd. All rights reserved.

  20. WECS Based Self-Excited Squirrel-Cage Induction Generator with Reduced Voltage Source Inverter Rating

    Directory of Open Access Journals (Sweden)

    O.Chandra sekha

    2014-07-01

    Full Text Available This paper presents the regulation of the voltage and frequency of a stand-alone fixed-pitch wind energy conversion system (WECS based on a self-excited squirrel-cage induction machine. A shunt connected voltage source inverter (VSI and a controllable dump load are used for regulation purposes. A battery bank is included in the dc side of the VSI so that it can absorb and inject active power thus increasing the efficiency and availability of the system. A control scheme for the VSI with self-governing control of real and reactive power allows the state of charge of the batteries to be kept in a safe range while maximizing the voltage regulating capabilities of the VSI. The characteristics of the wind turbine, selfexcited generator, and the ratings of the VSI are considered in order to find out the load range for which voltage and frequency can be regulated for a given wind speed range. The possibility of the proposed system is verified by MATLAB/SIMULINK. simulations.

  1. Comparison of changes in tidal volume associated with expiratory rib cage compression and expiratory abdominal compression in patients on prolonged mechanical ventilation.

    Science.gov (United States)

    Morino, Akira; Shida, Masahiro; Tanaka, Masashi; Sato, Kimihiro; Seko, Toshiaki; Ito, Shunsuke; Ogawa, Shunichi; Takahashi, Naoaki

    2015-07-01

    [Purpose] This study was designed to compare and clarify the relationship between expiratory rib cage compression and expiratory abdominal compression in patients on prolonged mechanical ventilation, with a focus on tidal volume. [Subjects and Methods] The subjects were 18 patients on prolonged mechanical ventilation, who had undergone tracheostomy. Each patient received expiratory rib cage compression and expiratory abdominal compression; the order of implementation was randomized. Subjects were positioned in a 30° lateral recumbent position, and a 2-kgf compression was applied. For expiratory rib cage compression, the rib cage was compressed unilaterally; for expiratory abdominal compression, the area directly above the navel was compressed. Tidal volume values were the actual measured values divided by body weight. [Results] Tidal volume values were as follows: at rest, 7.2 ± 1.7 mL/kg; during expiratory rib cage compression, 8.3 ± 2.1 mL/kg; during expiratory abdominal compression, 9.1 ± 2.2 mL/kg. There was a significant difference between the tidal volume during expiratory abdominal compression and that at rest. The tidal volume in expiratory rib cage compression was strongly correlated with that in expiratory abdominal compression. [Conclusion] These results indicate that expiratory abdominal compression may be an effective alternative to the manual breathing assist procedure.

  2. Outcomes of interbody fusion cages used in 1 and 2-levels anterior cervical discectomy and fusion: titanium cages versus polyetheretherketone (PEEK) cages.

    Science.gov (United States)

    Niu, Chi-Chien; Liao, Jen-Chung; Chen, Wen-Jer; Chen, Lih-Huei

    2010-07-01

    A prospective study was performed in case with cervical spondylosis who underwent anterior cervical discectomy and fusion (ACDF) with titanium or polyetheretherketone (PEEK) cages. To find out which fusion cage yielded better clinical and radiographic results. Although use of autogenous iliac-bone grafts in ACDF for cervical disc diseases remain standard surgical procedure, donor site morbidity and graft collapse or breakage are concerns. Cage technology was developed to prevent these complications. However, there is no comparison regarding the efficacy between titanium and PEEK cage. January 2005 to January 2006, 53 patients who had 1 and 2-levels ACDF with titanium or PEEK cages were evaluated. We measured the rate and amount of interspace collapse, segmental sagittal angulations, and the radiographic fusion success rate. Odom criteria were used to assess the clinical results. The fusion rate was higher in the PEEK group (100% vs. 86.5%, P=0.0335). There was no significant difference between both groups in loss of cervical lordosis (3.2 + or - 2.4 vs. 2.8 + or - 3.4, P=0.166). The mean anterior interspace collapse (1.6 + or - 1.0 mm) in the titanium group was significantly higher than the collapse of the PEEK group (0.5 + or - 0.6 mm) (PPEEK group (PPEEK group achieved an 80% rate of successful clinical outcomes, compared with 75% in the titanium group (P=0.6642). The PEEK cage is superior to the titanium cage in maintaining cervical interspace height and radiographic fusion after 1 and 2-levels anterior cervical decompression procedures.

  3. Integrated versus stand-alone second generation ethanol production from sugarcane bagasse and trash.

    Science.gov (United States)

    Dias, Marina O S; Junqueira, Tassia L; Cavalett, Otávio; Cunha, Marcelo P; Jesus, Charles D F; Rossell, Carlos E V; Maciel Filho, Rubens; Bonomi, Antonio

    2012-01-01

    Ethanol production from lignocellulosic materials is often conceived considering independent, stand-alone production plants; in the Brazilian scenario, where part of the potential feedstock (sugarcane bagasse) for second generation ethanol production is already available at conventional first generation production plants, an integrated first and second generation production process seems to be the most obvious option. In this study stand-alone second generation ethanol production from surplus sugarcane bagasse and trash is compared with conventional first generation ethanol production from sugarcane and with integrated first and second generation; simulations were developed to represent the different technological scenarios, which provided data for economic and environmental analysis. Results show that the integrated first and second generation ethanol production process from sugarcane leads to better economic results when compared with the stand-alone plant, especially when advanced hydrolysis technologies and pentoses fermentation are included. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. Biomechanics of Nested Transforaminal Lumbar Interbody Cages.

    Science.gov (United States)

    Soriano-Baron, Hector; Newcomb, Anna G U S; Malhotra, Devika; de Tranaltes, Kaylee; Martinez-Del-Campo, Eduardo; Reyes, Phillip M; Crawford, Neil R; Theodore, Nicholas; Tumialán, Luis M

    2016-02-01

    Arthrodesis is optimized when the structural graft occupies most of the surface area within a disc space. The transforaminal corridor inherently limits interbody size. To evaluate the biomechanical implications of nested interbody spacers (ie, a second curved cage placed behind a first) to increase disc space coverage in transforaminal approaches. Seven lumbar human cadaveric specimens (L3-S1) underwent nondestructive flexibility and axial compression testing intact and after transforaminal instrumentation at L4-L5. Specimens were tested in 5 conditions: (1) intact, (2) interbody, (3) interbody plus bilateral pedicle screws and rods (PSR), (4) 2 nested interbodies, and (5) 2 nested interbodies plus PSR. Mean range of motion (ROM) with 1 interbody vs 2 nested interbodies, respectively, was: flexion, 101% vs 85%; extension, 97% vs 92%; lateral bending, 127% vs 132%; and axial rotation, 145% vs 154%. One interbody and 2 nested interbodies did not differ significantly by loading mode (P > .10). With PSR, ROM decreased significantly compared with intact, but not between interbody and interbody plus PSR or 2 interbodies plus PSR (P > .80). Mean vertical height during compressive loading (ie, axial compressive stiffness) was significantly different with 2 nested interbodies vs 1 interbody alone (P < .001) (compressive stiffness, 89% of intact vs 67% of intact, respectively). Inserting a second interbody using a transforaminal approach is anatomically feasible and nearly doubles the disc space covered without affecting ROM. Compressive stiffness significantly increased with 2 nested interbodies, and foraminal height increased. Evaluation of the clinical safety and efficacy of nested interbodies is underway.

  5. Net-bottom Cage Inserts for Water Bird Casualties

    Directory of Open Access Journals (Sweden)

    Jackie Belle

    2017-10-01

    Full Text Available My Bright Idea is a net-bottomed cage insert, which is used to support pelagic avian casualties. The idea was designed and modified by the International Bird Rescue in California (Bird Rescue.

  6. Environmental impact analysis of aquaculture in net cages in a ...

    African Journals Online (AJOL)

    Environmental impact analysis of aquaculture in net cages in a Brazilian water reservoir, based in zooplankton communities. Maria Cristina Crispim, Karla Patrícia Ponte Araújo, Hênio do Nascimento Melo Júnior ...

  7. Sensorless direct voltage control of the stand-alone brushless doubly-fed generator

    DEFF Research Database (Denmark)

    Liu, Yi; Xu, Wei; Xiong, Fei

    2017-01-01

    The conventional stand-alone brushless doubly-fed generator (BDFG) control strategies need the feedback from the rotor position or speed sensors, which can reduce system reliability and increase the cost and axial volume of the machine. In this paper, a sensorless direct voltage control (DVC......) strategy is presented for the stand-alone BDFG. The satisfactory dynamic performance is verified by experimental results under four kinds of typical operation conditions. Besides, the proposed control strategy is robust due to no generator parameters being required....

  8. Photovoltaic Module Simulink Model for a Stand-alone PV System

    Science.gov (United States)

    Qi, Chen; Ming, Zhu

    Photovoltaic(PV) Module is indispensable of a stand-alone PV system. In this paper, a one-diode equivalent circuit-based versatile simulation model in the form of masked block PV module is proposed. By the model, it is allowed to estimate behavior of PV module with respect changes on irradiance intensity, ambient temperature and parameters of the PV module. In addition, the model is capable of function of Maximum Power Point Tracking (MPPT) which can be used in the dynamic simulation of stand-alone PV systems.

  9. A control strategy for stand-alone wound rotor induction machine

    Energy Technology Data Exchange (ETDEWEB)

    Forchetti, D.G.; Garcia, G.O. [Grupo de Electronica Aplicada (GEA), Universidad Nacional de Rio Cuarto, X5804 BYA Rio Cuarto (Argentina); Solsona, J.A. [Instituto de Investigaciones en Ingenieria Electrica?Alfredo Desages?, Departamento de Ingenieria Electrica y de Computadoras, Universidad Nacional del Sur, Bahia Blanca (Argentina); Valla, M.I. [Laboratorio de Electronica Industrial, Control e Instrumentacion (LEICI), Facultad de Ingenieria, Universidad Nacional de La Plata, 1900 La Plata (Argentina)

    2007-02-15

    A control strategy to regulate the frequency and voltage of a stand-alone wound rotor induction machine is presented. This strategy allows the machine to work as a generator in stand-alone systems (without grid connection) with variable rotor speed. A stator flux-oriented control is proposed using the rotor voltages as actuation variables. Two cascade control loops are used to regulate the stator flux and the rotor currents. A closed loop observer is designed to estimate the machine flux which is necessary to implement these control loops. The proposed control strategy is validated through simulations with satisfactory results. (author)

  10. Assessment of Stand-Alone Displays for Time Management in a Creativity-Driven Learning Environment

    DEFF Research Database (Denmark)

    Frimodt-Møller, Søren

    2017-01-01

    This paper considers the pros and cons of stand-alone displays, analog (e.g. billboards, blackboards, whiteboards, large pieces of paper etc.) as well as digital (e.g. large shared screens, digital whiteboards or similar), as tools for time management processes in a creativity-driven learning...... to storing information digitally. The findings could indicate a possible market for stand-alone, interactive digital displays combining the ‘touch and feel’ character of an analog board with the convenience of digital data storage....

  11. La cage qui cache : La Cage Dorée de Ruben Alves

    Directory of Open Access Journals (Sweden)

    Cristina Marinho

    2015-01-01

    Full Text Available The French Comedy La Cage Dorée (produced by the luso descendant Ruben Alves, 2013 success seems to be mainly due to its clichés of Portuguese epics in Paris, and its miseries may not have been underlined enough. Thus, under this apparently naif portrait an intriguing painting of Portuguese immigrants’ French dis-integration may really be hiding, which is the aim of this essay, on one hand, to bring out and, on the other one, to clarify, by questioning comparative critical common denominators of the two countries.

  12. La cage qui cache : La Cage Dorée de Ruben Alves

    Directory of Open Access Journals (Sweden)

    Cristina Marinho

    2015-12-01

    Full Text Available The French Comedy La Cage Dorée (produced by the luso descendant Ruben Alves, 2013 success seems to be mainly due to its clichés of Portuguese epics in Paris, and its miseries may not have been underlined enough. Thus, under this apparently naif portrait an intriguing painting of Portuguese immigrants’ French dis-integration may really be hiding, which is the aim of this essay, on one hand, to bring out and, on the other one, to clarify, by questioning comparative critical common denominators of the two countries.

  13. Caged molecular beacons: controlling nucleic acid hybridization with light.

    Science.gov (United States)

    Wang, Chunming; Zhu, Zhi; Song, Yanling; Lin, Hui; Yang, Chaoyong James; Tan, Weihong

    2011-05-28

    We have constructed a novel class of light-activatable caged molecular beacons (cMBs) that are caged by locking two stems with a photo-labile biomolecular interaction or covalent bond. With the cMBs, the nucleic acid hybridization process can be easily controlled with light, which offers the possibility for a high spatiotemporal resolution study of intracellular mRNAs. © The Royal Society of Chemistry 2011

  14. Musica come divenire. Il paesaggio sonoro secondo John cage

    Directory of Open Access Journals (Sweden)

    Francesca Aste

    2008-12-01

    Full Text Available John Cage ha dedicato tutta la sua vita all’indagine delle possibilità di relazione dell’uomo con i suoni che lo circondano, allargando il campo dell’arte musicale a quello dell’etica e dell’ecologia. Cage non si è occupato di soundscape come un genere compositivo specifico, come forse oggi potremmo identificarlo, tuttavia l’ambiente occupa un ruolo centrale in relazione al suo modo di comporre.

  15. Mitochondria mediate septin cage assembly to promote autophagy of Shigella.

    Science.gov (United States)

    Sirianni, Andrea; Krokowski, Sina; Lobato-Márquez, Damián; Buranyi, Stephen; Pfanzelter, Julia; Galea, Dieter; Willis, Alexandra; Culley, Siân; Henriques, Ricardo; Larrouy-Maumus, Gerald; Hollinshead, Michael; Sancho-Shimizu, Vanessa; Way, Michael; Mostowy, Serge

    2016-07-01

    Septins, cytoskeletal proteins with well-characterised roles in cytokinesis, form cage-like structures around cytosolic Shigella flexneri and promote their targeting to autophagosomes. However, the processes underlying septin cage assembly, and whether they influence S. flexneri proliferation, remain to be established. Using single-cell analysis, we show that the septin cages inhibit S. flexneri proliferation. To study mechanisms of septin cage assembly, we used proteomics and found mitochondrial proteins associate with septins in S. flexneri-infected cells. Strikingly, mitochondria associated with S. flexneri promote septin assembly into cages that entrap bacteria for autophagy. We demonstrate that the cytosolic GTPase dynamin-related protein 1 (Drp1) interacts with septins to enhance mitochondrial fission. To avoid autophagy, actin-polymerising Shigella fragment mitochondria to escape from septin caging. Our results demonstrate a role for mitochondria in anti-Shigella autophagy and uncover a fundamental link between septin assembly and mitochondria. © 2016 The Authors. Published under the terms of the CC BY 4.0 license.

  16. Caged Protein Prenyltransferase Substrates: Tools for Understanding Protein Prenylation

    Energy Technology Data Exchange (ETDEWEB)

    DeGraw, Amanda J.; Hast, Michael A.; Xu, Juhua; Mullen, Daniel; Beese, Lorena S.; Barany, George; Distefano, Mark D. (Duke); (UMM)

    2010-11-15

    Originally designed to block the prenylation of oncogenic Ras, inhibitors of protein farnesyltransferase currently in preclinical and clinical trials are showing efficacy in cancers with normal Ras. Blocking protein prenylation has also shown promise in the treatment of malaria, Chagas disease and progeria syndrome. A better understanding of the mechanism, targets and in vivo consequences of protein prenylation are needed to elucidate the mode of action of current PFTase (Protein Farnesyltransferase) inhibitors and to create more potent and selective compounds. Caged enzyme substrates are useful tools for understanding enzyme mechanism and biological function. Reported here is the synthesis and characterization of caged substrates of PFTase. The caged isoprenoid diphosphates are poor substrates prior to photolysis. The caged CAAX peptide is a true catalytically caged substrate of PFTase in that it is to not a substrate, yet is able to bind to the enzyme as established by inhibition studies and X-ray crystallography. Irradiation of the caged molecules with 350 nm light readily releases their cognate substrate and their photolysis products are benign. These properties highlight the utility of those analogs towards a variety of in vitro and in vivo applications.

  17. Homogenized boundary conditions and resonance effects in Faraday cages

    Science.gov (United States)

    Hewitt, I. J.

    2016-01-01

    We present a mathematical study of two-dimensional electrostatic and electromagnetic shielding by a cage of conducting wires (the so-called ‘Faraday cage effect’). Taking the limit as the number of wires in the cage tends to infinity, we use the asymptotic method of multiple scales to derive continuum models for the shielding, involving homogenized boundary conditions on an effective cage boundary. We show how the resulting models depend on key cage parameters such as the size and shape of the wires, and, in the electromagnetic case, on the frequency and polarization of the incident field. In the electromagnetic case, there are resonance effects, whereby at frequencies close to the natural frequencies of the equivalent solid shell, the presence of the cage actually amplifies the incident field, rather than shielding it. By appropriately modifying the continuum model, we calculate the modified resonant frequencies, and their associated peak amplitudes. We discuss applications to radiation containment in microwave ovens and acoustic scattering by perforated shells. PMID:27279775

  18. Preliminary experience of titanium mesh cages for pathological fracture of middle and lower cervical vertebrae.

    Science.gov (United States)

    Chuang, Hao-Che; Wei, Sung-Tai; Lee, Han-Chung; Chen, Chun-Chung; Lee, Wen-Yuen; Cho, Der-Yang

    2008-11-01

    The advantages and disadvantages of titanium mesh cages (TMCs) assisted by anterior cervical plates (ACPs) for interbody fusion following cervical corpectomy were investigated. Between January 2002 and September 2006, 17 patients with cervical radiculomyelopathy caused by metastasis-induced pathologic fractures were selected for anterior corpectomy. TMCs were inserted into the post-corpectomy defect and stabilized by placement of ACPs filled with Triosite. Post-operative plain X-ray films indicated maintenance of spinal stability. No ceramic, donor site or surgery-related complications were observed. True trabeculation was observed in axial and reconstructive CT scans in all surviving patients one year after surgery. Neurological recovery, pain control, and good quality of life were achieved. Short hospital stays, minimal blood loss, short operation times and brief periods of bed confinement were also observed. We conclude that a TMC assisted by an ACP is safe and effective for interbody fusion following cervical corpectomy for pathological fractures resulting from cervical vertebral metastases.

  19. TiN thin film deposition by cathodic cage discharge: effect of cage configuration and active species

    International Nuclear Information System (INIS)

    De Freitas Daudt, N; Cavalcante Braz, D; Alves Junior, C; Pereira Barbosa, J C; Barbalho Pereira, M

    2012-01-01

    Plasma cathodic cage technique was developed recently in order to eliminate phenomena such as edge effects and overheating, which occur during conventional nitriding processes. In this work, the effect of plasma active species and cage configurations during thin film deposition of TiN were studied. This compound was chosen because its properties are very sensitive to slight variations in chemical composition and film thickness, becoming a good monitoring tool in fabrication process control. In order to verify the effect of cage geometry on the discharge and characteristics of the grown film, a cage made of titanium was used with different numbers and distribution of holes. Furthermore, different amounts of hydrogen were added to the Ar + N2 plasma atmosphere. Flow rates of Ar and N2 gas were fixed at 4 and 3 sccm, respectively and flow rates of H 2 gas was 0, 1 and 2 sccm. Plasma species, electrical discharge and physical characteristics of the grown film were analyzed by Optical Emission Spectroscopy (OES), Atomic Force Microscopy (AFM), X-Ray Diffraction. It was observed by OES that the luminous intensity associated to Hα species is not proportional to flow rate of H 2 gas. Electrical efficiency of the system, crystal structure and topography of the TiN film are strongly influenced by this behavior. For constant flow rate of H 2 gas, it was found that with more holes at the top of the cage, deposition rate, crystallinity and roughness are higher, if compared to cages with a small number of holes at the top of cage. On the other hand, the opposite behavior was observed when more holes were located at the sidewall of cage.

  20. Subsidence of polyetheretherketone cage after minimally invasive transforaminal lumbar interbody fusion.

    Science.gov (United States)

    Kim, Moon-Chan; Chung, Hung-Tae; Cho, Jae-Lim; Kim, Dong-Jun; Chung, Nam-Su

    2013-04-01

    A retrospective case series. The aim of this study was to determine the rate of cage subsidence after minimally invasive transforaminal lumbar interbody fusion (MITLIF) conducted using a polyetheretherketone (PEEK) cage, and to identify associated risk factors. Although various rates of cage subsidence after lumbar interbody fusion have been reported, few studies have addressed subsidence rate after MITLIF using PEEK cage. A total of 104 consecutive patients who had undergone MITLIF using a PEEK cage with a minimum follow-up of 2 years were included in this study. Cage subsidence was defined to have occurred when a cage was observed to sink into an adjacent vertebral body by ≥2 mm on the postoperative or serial follow-up lateral radiographs. The demographic variables considered to affect cage subsidence were the following: age, sex, body mass index, bone mineral density, diagnosis, number of fusion segment, and the quality/quantity of back muscle, and the cage-related variables considered were: level of fusion, intervertebral angle, cage size, cage position, and postoperative distraction of disc height. Logistic regression analysis was conducted to explore relations between these variables and cage subsidence. : For the 122 cages inserted, the rate of cage subsidence was 14.8% (18 cages), and cage subsidence occurred within 7.2±8.5 (1-25) months of surgery. The odds ratios for factors found to significantly increase the risk of cage subsidence were; 1.950 (95% confidence interval, 1.002-4.224) for L5-S1 level, and 1.018 (95% confidence interval, 1.000-1.066) for anterior cage position. The rate of PEEK cage subsidence after MITLIF was relatively low. End-plate manipulation and cage insertion during MITLIF were not influenced by a small operation window.

  1. Multicomponent Protein Cage Architectures for Photocatalysis

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Arunava [Univ. of Alabama, Tuscaloosa, AL (United States); Prevelige, Peter E [Univ. of Alabama, Birmingham, AL (United States)

    2016-01-04

    The primary goal of the project was to develop protein-templated approaches for the synthesis and directed assembly of semiconductor nanomaterials that are efficient for visible light absorption and hydrogen production. In general, visible-light-driven photocatalysis reactions exhibit low quantum efficiency for solar energy conversion primarily because of materials-related issues and limitations, such as the control of the band gap, band structure, photochemical stability, and available reactive surface area of the photocatalyst. Synthesis of multicomponent hierarchical nano-architectures, consisting of semiconductor nanoparticles (NPs) with desired optical properties fabricated to maximize spatial proximity for optimum electron and energy transfer represents an attractive route for addressing the problem. Virus capsids are highly symmetrical, self-assembling protein cage nanoparticles that exist in a range of sizes and symmetries. Selective deposition of inorganic, by design, at specific locations on virus capsids affords precise control over the size, spacing, and assembly of nanomaterials, resulting in uniform and reproducible nano-architectures. We utilized the self-assembling capabilities of the 420 subunit, 60 nm icosahedral, P22 virus capsid to direct the nucleation, growth, and proximity of a range of component materials. Controlled fabrication on the exterior of the temperature stable shell was achieved by genetically encoding specific binding peptides into an externally exposed loop which is displayed on each of the 420 coat protein subunits. Localization of complimentary materials to the interior of the particle was achieved through the use “scaffolding-fusion proteins. The scaffolding domain drives coat protein polymerization resulting in a coat protein shell surrounding a core of approximately 300 scaffolding/fusion molecules. The fusion domain comprises a peptide which specifically binds the semiconductor material of interest.

  2. Linguistic and Structural Analyses of Stand-Alone Literature Reviews: Seventy-Five Years of Change

    Science.gov (United States)

    Wright, Heidi Rachel

    2016-01-01

    The purpose of this dissertation is to offer a multifaceted overview of stand-alone literature reviews. These texts, literature reviews published unattached to research articles, have existed for centuries but remained largely unstudied by linguists. Thus, the goal of this project is to present these reviews' situational, grammatical, and…

  3. Evaluating a Pre-Session Homework Exercise in a Standalone Information Literacy Class

    Science.gov (United States)

    Goetz, Joseph E.; Barber, Catherine R.

    2015-01-01

    In this study, researchers evaluate a homework exercise assigned before a standalone information literacy session. Students in a Master of Education program completed a worksheet using the ERIC database thesaurus. The researchers conducted pre- and posttests within a single library session to assess student learning, using a control group for…

  4. Design and Operation Studies of A Stand-Alone PV Generation System

    DEFF Research Database (Denmark)

    Hu, Yanting; Chen, Zhe; Zhang, Donglai

    2013-01-01

    This paper discusses the modeling, design and operation of a PV powered stand-alone system, which includes a PV array, a battery bank, power electronic converters and the associated control system. The design considerations are analyzed and a design platform is presented. Furthermore the operatio...

  5. Clinical outcome of stand-alone ALIF compared to posterior instrumentation for degenerative disc disease

    DEFF Research Database (Denmark)

    Udby, Peter M.; Bech-Azeddine, Rachid

    2015-01-01

    low back pain resulting from degenerative disc disease. ALIF surgery has previously been linked with certain high risk complications and unfavorable long term fusion results. Newer studies suggest that stand-alone ALIF can possibly be advantageous compared to other types of posterior instrumented...

  6. Environmental/Climatic Effect on Stand-Alone Solar Energy Supply ...

    African Journals Online (AJOL)

    This paper investigates the climatic eects and environmental variations on the performance of a stand-alone photovoltaic system. The eects of partial shading with dierent climate conditions and load resistance variations were examined. A survey of some of the work done in this eld of environmental eect on solar panel was ...

  7. MOSFET Loss Evaluation for a Low-Power Stand-Alone Photovoltaic-LED System

    DEFF Research Database (Denmark)

    Mira Albert, Maria del Carmen; Knott, Arnold; Andersen, Michael A. E.

    2015-01-01

    This paper presents a performance evaluation and comparison of state-of-the-art low voltage Si MOSFETs for a stand-alone photovoltaic-LED Light to Light (LtL) system. The complete system is formed by two cascaded converters that will be optimized for a determined solar irradiation and LED...

  8. Integrated Three-Port DC-DC Converter for Photovoltaic (PV) Battery Stand-alone Systems

    DEFF Research Database (Denmark)

    Ouyang, Ziwei; Andersen, Michael A. E.

    2016-01-01

    Several power sources such as PV solar arrays and battery are often used to manage the power flow for a photovoltaic (PV) based stand-alone power system due to the fluctuation nature of solar energy resource, and deliver a continuous power to the users in an appropriate form. Traditionally, three...

  9. Assessment of renewable energy resources potential for large scale and standalone applications in Ethiopia

    NARCIS (Netherlands)

    Tucho, Gudina Terefe; Weesie, Peter D.M.; Nonhebel, Sanderine

    2014-01-01

    This study aims to determine the contribution of renewable energy to large scale and standalone application in Ethiopia. The assessment starts by determining the present energy system and the available potentials. Subsequently, the contribution of the available potentials for large scale and

  10. Discrete-Time Domain Modelling of Voltage Source Inverters in Standalone Applications

    DEFF Research Database (Denmark)

    Federico, de Bosio; de Sousa Ribeiro, Luiz Antonio; Freijedo Fernandez, Francisco Daniel

    2017-01-01

    The decoupling of the capacitor voltage and inductor current has been shown to improve significantly the dynamic performance of voltage source inverters in standalone applications. However, the computation and PWM delays still limit the achievable bandwidth. In this paper a discrete-time domain...

  11. Stand-alone version of the 11kW Gaia wind turbine

    DEFF Research Database (Denmark)

    Bindner, H.; Rosas, P.A.C.; Teodorescu, R.

    2004-01-01

    This report describes the development of a stand-alone version of the 11kW Gaia wind turbine. Various possible configurations are investigated and a configuration using a back-to-back converter is chosen. A model is developed for controller design of thefast controllers of the unit. Controllers...... assessment and controller design a dynamic performance assessment model has been developed....

  12. A maximum power point tracking scheme for a 1kw stand-alone ...

    African Journals Online (AJOL)

    A maximum power point tracking scheme for a 1kw stand-alone solar energy based power supply. ... This paper elucidates one of the tracking schemes for a photovoltaic (PV) systems using Cuk converter operating in discontinuous inductor current mode (DICM) as an interface. A method for efficiently maximizing the output ...

  13. Analysis and controller design for stand-alone VSIs in synchronous reference frame

    DEFF Research Database (Denmark)

    Ramezani, Malek; Li, Shuhui; Golestan, Saeed

    2017-01-01

    The common practice for controlling the stand-alone voltage source inverters (VSIs) is to transform abc voltage and current signals to DC signals using the dq transformation, which makes it possible to control the new DC voltage and current signals just using simple proportional-integral controll...

  14. Demonstration of Load-Follow Simulation with VERA-CS and Standalone BISON

    Energy Technology Data Exchange (ETDEWEB)

    Stimpson, Shane G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-01-24

    In this report, load-follow simulations using VERA-CS with one-way coupling to standalone BISON has been demonstrated including both a single rod with a full cycle of load-follow operations and a quarter-core model with a single month of load-follow.

  15. Stand-alone wind system with Vanadium Redox Battery energy storage

    DEFF Research Database (Denmark)

    Teodorescu, Remus; Barote, L.; Weissbach, R.

    2008-01-01

    Energy storage devices are required for power balance and power quality in stand alone wind energy systems. A Vanadium Redox Flow Battery (VRB) system has many features which make its integration with a stand-alone wind energy system attractive. This paper proposes the integration of a VRB system...

  16. CAGE BREEDING OF WARM WATER FRESHWATER FISH SPECIES

    Directory of Open Access Journals (Sweden)

    Roman Safner

    2008-10-01

    Full Text Available In the 1970s, Croatia became actively involved in the contemporary trend of breeding fish in floating cages. In addition to various species of marine fishes, breeding was attempted with trout, carp, catfish, cisco and salmon. Of the above freshwater fish species, specific standards were established only for the cage breeding of rainbow trout. Cage breeding of the remaining species remained at the level of occasional attempts, with more of an experimental than a commercial character. The regular attempts to master this technique for cage breeding of warm water freshwater fish species were aimed at achieving the known benefits of such breeding, such as simplicity of implementing technological measures, easier establishment of the breeding system, simpler manipulation, the possibility of denser colonies per unit volume with a high level of production, easier adaptations to market conditions and fewer initial structural investments. Despite the many advantages, the main reasons for the lack of greater implementation of the cage breeding technology for warm water species of freshwater fish include problems in obtaining the appropriate category and quantity of healthy fry, the specificity and applicability of physical and chemical properties of the recipients and human error. In evaluating the advantages and disadvantages, the final decision on the justification of cage breeding for individual warm water freshwater species must be based on both biological and economic factors. Based on the knowledge of cage breeding acquired to date, the rule for virtually all intensive breeding systems is that it is only recommended for those species with high market demand and a high market price. The technology that demands nutrition with highly concentrated feed and other production expenditures is costly, and is therefore not profitable with less expensive fish species. Furthermore, production must be market oriented, i.e. the appropriate market research measures

  17. Anterior lumbar interbody fusion using a barbell-shaped cage: a biomechanical comparison.

    Science.gov (United States)

    Murakami, H; Boden, S D; Hutton, W C

    2001-10-01

    There are drawbacks to using threaded cylindrical cages (e.g., limited area for bone ingrowth and metal precluding radiographic visualization of bone healing). To somewhat offset these drawbacks, a barbell-shaped cage has been designed. The central core of the barbell can be wrapped with collagen sheets infiltrated with bone morphogenetic protein. The obvious theoretical advantages of a barbell cage have to be weighed against potential biomechanical disadvantages. Our purpose was to compare the biomechanical properties of an anterior lumbar interbody reconstruction using 18-mm-diameter threaded cylindrical cages, with a reconstruction using barbell cages (18-mm diameter and 6 mm wide at both cylindrical ends, with a round 4-mm-diameter bar joining the two ends). Twelve cadaveric lumbar motion segments were tested. Three L5-S1 segments received two threaded cylindrical cages, and three L5-S1 segments received two barbell cages. Three L3-L4 segments received one threaded cylindrical cage, and three L3-L4 segments received one barbell cage. A series of biomechanical loading sequences were carried out on each motion segment, and stiffness curves were obtained. After the biomechanical testing, an axial compressive load was applied to the motion segments until failure. They were then radiographed and bisected through the disc, and the subsidence (or penetration) of the cage(s) in the cancellous bone of the vertebral bodies was measured. There was no difference in terms of stiffness between the motion segments with the threaded cylindrical cage(s) inserted and those with the barbell cage(s) inserted (p > 0.15). The average values of subsidence was 0.96 mm for the threaded cylindrical cage group and 0.80 mm for the barbell cage group (difference not significant: p = 0.38). The results suggest that a reconstruction using barbell cages is a biomechanically acceptable alternative to one using threaded cylindrical cages.

  18. High levitation pressures with cage-cooled superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Hull, John R. [Energy Technology Division, Argonne National Laboratory, Argonne, IL (United States); Komori, Mochimitsu [Department of Mechanical Systems Engineering, Kyushu Institute of Technology, Iizuka, Fukuoka (Japan)

    2002-05-01

    We present an analysis of and experimental results from a levitational system comprising a stationary, bulk high-temperature superconductor (HTS) and a levitated component (rotor) that consists of a cylindrical permanent magnet surrounded by an annular HTS. The rotor is cooled below the critical temperature of the HTS while surrounded by a ferromagnetic cage. When the ferromagnetic cage is removed, the flux from the permanent magnet is essentially excluded from the interior of the HTS. When brought into proximity with the HTS stator, the cage-cooled rotor experiences a levitational force. The levitational force may be calculated by applying magnetic circuit theory. Such calculations indicate that for a sufficiently high critical current density, the levitational pressure may exceed that between the permanent magnet and its mirror image. We constructed a rotor from an NdFeB permanent magnet and YBCO bulk HTS with a critical current density of {approx}5 kA cm{sup -2}. A soft ferromagnetic steel cage was constructed in segments. The critical current density of the stator HTS was also {approx}5 kA cm{sup -2}. Experimental results obtained with the cage-cooled rotor and stationary HTS show a significant increase in force over that of an equivalent PM rotor and stationary HTS. (author)

  19. PROBLEMS OF BIOFOULING ON FISH–CAGE NETS IN AQUACULTURE

    Directory of Open Access Journals (Sweden)

    Merica Slišković

    2002-09-01

    Full Text Available Biofouling on fish–cage netting is a serious technical and economical problem to aquaculture worldwide. Compensation for the effects of biofouling must be included in cage system design and planning, as fouling can dramatically increase both weight and drag. Settlements of sessile plants and animals, with accumulation of the detritus diminish the size of mesh and can rapidly occlude mesh. Negative effect of smaller mesh size is changing in water flow trough the cages. Biofouling problems necessitating purchase of a second sets of nets or more, and frequent cleaning and changing of biofouling. Changing and cleaning frequency depend on many factors such as: location of cages (near the coast or off shore, productivity of that location, time of the year, time period in which the cages are placed on that location (cause of loading of phosphorus and nitrogen from the unconsumed food in the sediment. Net changing and cleaning procedures are labor and capital intensive. Process of the cleaning of the nets is inadequate, especially when there isnžt adequate equipment available as it is case in smaller aquaculture industry. Chemical control of biofouling e. g. use of antifoulants is questioningly cause of their possible negative effects on breeding species and environment.

  20. An optimized Faraday cage design for electron beam current measurements

    International Nuclear Information System (INIS)

    Turner, J.N.; Hausner, G.G.; Parsons, D.F.

    1975-01-01

    A Faraday cage detector is described for measuring electron beam intensity for use with energies up to 1.2 Mev, with the present data taken at 100 keV. The design features a readily changeable limiting aperture and detector cup geometry, and a secondary electron suppression grid. The detection efficiency of the cage is shown to be limited only by primary backscatter through the detector solid angle of escape, which is optimized with respect to primary backscattered electrons and secondary electron escape. The geometry and stopping material of the detection cup are varied, and the results show that for maximum detection efficiency with carbon as the stopping mateiral, the solid angle of escape must be equal to or less than 0.05πsr. The experimental results are consistent within the +-2% accuracy of the detection electronics, and are not limited by the Faraday cage detection efficiency. (author)

  1. (reprocessed)CAGE_peaks_annotation - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us FANTOM5 (reprocessed)CAGE_peaks_annotation Data detail Data name (reprocessed)CAGE_peaks_ann...rence sequences (hg38/mm10). Data file File name: (reprocessed)CAGE_peaks_annotation (Homo sapiens) File URL...: ftp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/reprocessed/hg38_latest/extra/CAGE_peaks_annotation/ ...File size: 16 MB File name: (reprocessed)CAGE_peaks_annotation (Mus musculus) Fil...e URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/reprocessed/mm10_latest/extra/CAGE_peaks_annotat

  2. (reprocessed)CAGE peaks - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us FANTOM5 (reprocessed)CAGE peaks Data detail Data name (reprocessed)CAGE peaks DOI 10.18908/l...g38/mm10). Data file File name: (reprocessed)CAGE_peaks (Homo sapiens) File URL: ftp://ftp.biosciencedbc.jp/...archive/fantom5/datafiles/reprocessed/hg38_latest/extra/CAGE_peaks/ File size: 11 MB File name: (reprocessed...)CAGE_peaks (Mus musculus) File URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/reprocess...his Database Site Policy | Contact Us (reprocessed)CAGE peaks - FANTOM5 | LSDB Archive ...

  3. (reprocessed)CAGE_peaks_expression - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us FANTOM5 (reprocessed)CAGE_peaks_expression Data detail Data name (reprocessed)CAGE_peaks_exp... (hg38/mm10). Data file File name: (reprocessed)CAGE_peaks_expression (Homo sapiens) File URL: ftp://ftp.bio...sciencedbc.jp/archive/fantom5/datafiles/reprocessed/hg38_latest/extra/CAGE_peaks_expression/ File size: 3.3 GB File name: (reprocess...tp.biosciencedbc.jp/archive/fantom5/datafiles/reprocessed/mm10_latest/extra/CAGE_peaks_expression/ File size...f This Database Site Policy | Contact Us (reprocessed)CAGE_peaks_expression - FANTOM5 | LSDB Archive ...

  4. Chaotic Dynamics of Cage Behavior in a High-Speed Cylindrical Roller Bearing

    Directory of Open Access Journals (Sweden)

    Long Chen

    2016-01-01

    Full Text Available This paper presents a mathematical model to investigate the nonlinear dynamic behavior of cage in high-speed cylindrical bearing. Variations of cage behavior due to varying cage eccentricity and cage guidance gap are observed. Hydrodynamic behavior in cage contacts is taken into consideration for a more realistic calculation of acting forces owing to high working speed. Analysis of real-time cage dynamic behavior on radial plane is carried out using chaos theory based on the theoretical and mathematical model established in the paper. The analytical results of this paper provide a solid foundation for designing and manufacturing of high-speed cylindrical roller bearing.

  5. Polyetheretherketone (PEEK) cages in cervical applications: a systematic review.

    Science.gov (United States)

    Kersten, Roel Frederik Mark Raymond; van Gaalen, Steven M; de Gast, Arthur; Öner, F Cumhur

    2015-06-01

    Polyetheretherketone (PEEK) cages have been widely used during the past decade in patients with degenerative disorders of the cervical spine. Their radiolucency and low elastic modulus make them attractive attributes for spinal fusion compared with titanium and bone graft. Still, limitations are seen such as pseudoarthrosis, subsidence, and migration of the cages. Limited evidence on the clinical outcome of PEEK cages is found in the literature other than noncomparative cohort studies with only a few randomized controlled trials. To assess the clinical and radiographic outcome of PEEK cages in the treatment of degenerative disc disorders and/or spondylolisthesis in the cervical spine. Systematic review of all randomized controlled trials and prospective and retrospective nonrandomized comparative studies with a minimum follow-up of 6 months and all noncomparative cohort studies with a long-term follow-up of more than 5 years. The primary outcome variable was clinical performance. Secondary outcome variables consisted of radiographic scores. The MEDLINE, EMBASE, and Cochrane Library databases were searched according to the Preferred Reporting Items of Systematic reviews and Meta-Analyses statement and Meta-analysis Of Observational Studies in Epidemiology guidelines. No conflict of interest reported. No funding received. A total of 223 studies were identified, of which 10 studies were included. These comprised two randomized controlled trials, five prospective comparative trials, and three retrospective comparative trials. Minimal evidence for better clinical and radiographic outcome is found for PEEK cages compared with bone grafts in the cervical spine. No differences were found between PEEK, titanium, and carbon fiber cages. Future studies are needed to improve methodology to minimize bias. Publication of lumbar interbody fusion studies needs to be promoted because differences in clinical and/or radiographic scores are more likely to be demonstrated in this part

  6. 14C-age tracers in global ocean circulation models

    Science.gov (United States)

    Koeve, W.; Wagner, H.; Kähler, P.; Oschlies, A.

    2014-10-01

    The natural abundance of 14C in total CO2 dissolved in seawater is a property applied to evaluate the water age structure and circulation in the ocean and in ocean models. In this study we use three different representations of the global ocean circulation augmented with a suite of idealised tracers to study the potential and limitations of using natural 14C to determine water age, the time elapsed since a body of water had contact with the atmosphere. We find that, globally, bulk 14C-age is dominated by two equally important components, one associated with aging, i.e. the time component of circulation and one associated with a "preformed 14C-age". This latter quantity exists because of the slow and incomplete atmosphere/ocean equilibration of 14C in particular in high latitudes where many water masses form. The relative contribution of the preformed component to bulk 14C-age varies regionally within a given model, but also between models. Regional variability, e.g. in the Atlantic Ocean is associated with the mixing of waters with very different end members of preformed 14C-age. In the Atlantic, variations in the preformed component over space and time mask the circulation component to an extent that its patterns are not detectable from bulk 14C-age alone. Between models the variability of age can also be considerable (factor of 2), related to the combinations of physical model parameters, which influence circulation dynamics, and gas exchange in the models. The preformed component was found to be very sensitive to gas exchange and moderately sensitive to ice cover. In our model evaluation exercise, the choice of the gas exchange constant from within the current range of uncertainty had such a strong influence on preformed and bulk 14C-age that if model evaluation would be based on bulk 14C-age it could easily impair the evaluation and tuning of a models circulation on global and regional scales. Based on the results of this study, we propose that considering

  7. Fusion and subsidence rate of stand alone anterior lumbar interbody fusion using PEEK cage with recombinant human bone morphogenetic protein-2.

    Science.gov (United States)

    Behrbalk, Eyal; Uri, Ofir; Parks, Ruth M; Musson, Rachel; Soh, Reuben Chee Cheong; Boszczyk, Bronek Maximilian

    2013-12-01

    Anterior lumbar interbody fusion (ALIF) is an established treatment for structural instability associated with symptomatic disk degeneration (SDD). Stand-alone ALIF offers many advantages, however, it may increase the risk of non-union. Recombinant human bone morphogenetic protein-2 (BMP-2) may enhance fusion rate but is associated with postoperative complication. The optimal dose of BMP-2 remains unclear. This study assessed the fusion and subsidence rates of stand-alone ALIF using the SynFix-LR interbody cage with 6 ml/level of BMP-2. Thirty-two ALIF procedures were performed by a single surgeon in 25 patients. Twenty-five procedures were performed for SDD without spondylolisthesis (SDD group) and seven procedures were performed for SDD with grade-I olisthesis (SDD-olisthesis group). Patients were followed-up for a mean of 17 ± 6 months. Solid fusion was achieved in 29 cases (90.6 %) within 6 months postoperatively. Five cases of implant subsidence were observed (16 %). Four of these occurred in the SDD-olisthesis group and one occurred in the SDD group (57 % vs. 4 % respectively; p = 0.004). Three cases of subsidence failed to fuse and required revision. The body mass index of patients with olisthesis who developed subsidence was higher than those who did not develop subsidence (29 ± 2.6 vs. 22 ± 6.5 respectively; p = 0.04). No BMP-2 related complications occurred. The overall fusion rate of stand-alone ALIF using the SynFix-LR system with BMP-2 was 90.6 %, comparable with other published series. No BMP-2 related complication occurred at a dose of 6 mg/level. Degenerative spondylolisthesis and obesity seemed to increase the rate of implant subsidence, and thus we believe that adding posterior fusion for these cases should be considered.

  8. Modeling and Control of the Distributed Power Converters in a Standalone DC Microgrid

    Directory of Open Access Journals (Sweden)

    Xiaodong Lu

    2016-03-01

    Full Text Available A standalone DC microgrid integrated with distributed renewable energy sources, energy storage devices and loads is analyzed. To mitigate the interaction among distributed power modules, this paper describes a modeling and control design procedure for the distributed converters. The system configuration and steady-state analysis of the standalone DC microgrid under study are discussed first. The dynamic models of the distributed converters are then developed from two aspects corresponding to their two operating modes, device-regulating mode and bus-regulating mode. Average current mode control and linear compensators are designed accordingly for each operating mode. The stability of the designed system is analyzed at last. The operation and control design of the system are verified by simulation results.

  9. Stand-alone wind system with Vanadium Redox Battery energy storage

    DEFF Research Database (Denmark)

    Teodorescu, Remus; Barote, L.; Weissbach, R.

    2008-01-01

    Energy storage devices are required for power balance and power quality in stand alone wind energy systems. A Vanadium Redox Flow Battery (VRB) system has many features which make its integration with a stand-alone wind energy system attractive. This paper proposes the integration of a VRB system...... with a typical stand-alone wind energy system during wind speed variation as well as transient performance under variable load. The investigated system consists of a variable speed wind turbine with permanent magnet synchronous generator (PMSG), diode rectifier bridge, buck-boost converter, bidirectional charge...... controller, transformer, inverter, ac loads and VRB (to store a surplus of wind energy and to supply power during a wind power shortage). The main purpose is to supply domestic appliances through a single phase 230V, 50Hz inverter. Simulations are accomplished in order to validate the stability of the supply....

  10. Stand-alone version of the 11kW Gaia wind turbine

    Energy Technology Data Exchange (ETDEWEB)

    Bindner, H.; Rosas, P.A.C.; Teodorescu, R.; Blaabjerg, F.

    2004-09-15

    This report describes the development of a stand-alone version of the 11kW Gaia wind turbine. Various possible configurations are investigated and a configuration using a back-to-back converter is chosen. A model is developed for controller design of the fast controllers of the unit. Controllers are designed and a prototype is built for testing. The report documents the performance of the prototype through measurements done on the full scale prototype installed in a test facility where it has been tested both as a standalone unit and in parallel with a diesel genset. For system wide power quality assessment and controller design a dynamic performance assessment model has been developed. (au)

  11. Optimally sizing of solar array and battery in a standalone photovoltaic system in Malaysia

    Energy Technology Data Exchange (ETDEWEB)

    Shen, W.X. [School of Engineering, Monash University Malaysia, Jalan Lagoon Selatan, 46150 Bandar Sunway, Selangor Darul Ehsan (Malaysia)

    2009-01-15

    Size optimization of solar array and battery in a standalone photovoltaic (SPV) system is investigated. Based on the energy efficiency model, the loss of power supply probability (LPSP) of the SPV system is calculated for different size combinations of solar array and battery. For the desired LPSP at the given load demand, the optimal size combination is obtained at the minimum system cost. One case study is given to show the application of the method in Malaysian weather conditions. (author)

  12. Graft subsidence as a predictor of revision surgery following stand-alone lateral lumbar interbody fusion.

    Science.gov (United States)

    Tempel, Zachary J; McDowell, Michael M; Panczykowski, David M; Gandhoke, Gurpreet S; Hamilton, D Kojo; Okonkwo, David O; Kanter, Adam S

    2018-01-01

    OBJECTIVE Lateral lumbar interbody fusion (LLIF) is a less invasive surgical option commonly used for a variety of spinal conditions, including in high-risk patient populations. LLIF is often performed as a stand-alone procedure, and may be complicated by graft subsidence, the clinical ramifications of which remain unclear. The aim of this study was to characterize further the sequelae of graft subsidence following stand-alone LLIF. METHODS A retrospective review of prospectively collected data was conducted on consecutive patients who underwent stand-alone LLIF between July 2008 and June 2015; 297 patients (623 levels) met inclusion criteria. Imaging studies were examined to grade graft subsidence according to Marchi criteria, and compared between those who required revision surgery and those who did not. Additional variables recorded included levels fused, DEXA (dual-energy x-ray absorptiometry) T-score, body mass index, and routine demographic information. The data were analyzed using the Student t-test, chi-square analysis, and logistic regression analysis to identify potential confounding factors. RESULTS Of 297 patients, 34 (11.4%) had radiographic evidence of subsidence and 18 (6.1%) required revision surgery. The median subsidence grade for patients requiring revision surgery was 2.5, compared with 1 for those who did not. Chi-square analysis revealed a significantly higher incidence of revision surgery in patients with high-grade subsidence compared with those with low-grade subsidence. Seven of 18 patients (38.9%) requiring revision surgery suffered a vertebral body fracture. High-grade subsidence was a significant predictor of the need for revision surgery (p subsidence following stand-alone LLIF required revision surgery. When evaluating patients for LLIF, supplemental instrumentation should be considered during the index surgery in patients with a significant risk of graft subsidence.

  13. A Three-Port Topology Comparison for a Low Power Stand-Alone Photovoltaic System

    DEFF Research Database (Denmark)

    Mira Albert, Maria del Carmen; Knott, Arnold; Andersen, Michael A. E.

    2014-01-01

    Three-port converter (TPC) topologies for renewable energy systems aim to provide higher efficiency and power density than conventional cascaded structures. This work proposes an analytical comparison of different TPC topologies for a photovoltaic LED lamp stand-alone system. A comparison using...... component stress factor (CSF) is performed, which gives a quantitative measure of the performance of the converter. The candidate topologies are compared to each other according to a defined LED lighting strategy and a solar irradiation profile....

  14. (reprocessed)HeliscopeCAGE sequencing, Delve mapping and CAGE TSS aggregation - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us FANTOM5 (reprocessed)HeliscopeCAGE sequencing, Delve mapping and CAGE TSS aggregation Data detail Data name (reproces...ls.zip File size: 237 KB File name: (reprocessed)basic (Homo sapiens) File URL: f...tp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/reprocessed/hg38_latest/basic/ File size: 1.4 TB File name: (reprocess...ed)basic (Mus musculus) File URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/reprocess...A format) About This Database Database Description Download License Update History of This Database Site Policy | Contact Us (reproce

  15. Impacts of cage culture on physico-chemical and bacteriological ...

    African Journals Online (AJOL)

    The effects of cage fish farming on physico-chemical and bacteriological water quality in Lake Volta, Ghana, were investigated in 2013–2014. Farmed ... The bacteriological analysis, however, revealed contamination of the lake water by fish farming. ... Keywords: aquaculture, contamination, fish farming, large lake, pollution ...

  16. Diet manipulation and post-moulting responses in caged ...

    African Journals Online (AJOL)

    Two hundred and fifty caged commercial laying hens were induced to moult through a 15-day feed and water withdrawal programme. Immediate and subsequent effects on egg production and follicular developments were monitored. Results showed that moulted hens attained over 60% egg production after 6 weeks of ...

  17. Clathrates - An Exploration of the Chemistry of Caged Compounds

    Indian Academy of Sciences (India)

    The hollow cage structure are made up of hexagonal and pentagonal homo- atomic shells of carbon. Twenty hexagons and twelve isolated pentagons interact to .... The guests are generally alkali and alkaline-earth atoms. The cavity size of Si and Ge are compa- rable only with those ofNa+ ofK+ and compounds like KgGe.

  18. Regioselective nitration of aromatic substrates in zeolite cages

    Indian Academy of Sciences (India)

    Phenol is nitrated regioselectively by fuming nitric acid inside the cages of faujasite zeolites (dependent on the loading level) and a remarkable orthoselectivity is observed in solid state nitration. Toluene and chlorobenzene also containing ortho-/para-orienting substituents, undergo faster nitration, though the ...

  19. power generation and control of a self excited squirrel cage ...

    African Journals Online (AJOL)

    HOD

    powering customers isolated from the utility grid by wind energy because it derives its excitation from its own output terminal and neither an ... mechanically to the rotor of a squirrel cage induction which is fed with grid powerthat the generator supplies. A back ... than a conventional synchronous generator in micro- hydro and ...

  20. Power generation and control of a self excited squirrel cage ...

    African Journals Online (AJOL)

    The self-excited squirrel cage induction generator (SEIG) is frequently considered as the most economical solution for powering customers isolated from the utility grid by wind energy because it derives its excitation from its own output terminal and neither an exciter nor voltage regulator is required. Its major drawbacks ...

  1. Fish cage culture catches on in Nepal | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-10-25

    Oct 25, 2010 ... Fish Cage Culture in Nepal: from Displacement to Development An audio slideshow. Success Stories in Asian Aquaculture The stories presented in this book reflect the unique nature of Asian aquaculture, providing first-time insight into how and why it has become so successful. Utilizing Different Aquatic ...

  2. utilization of ensiled metabolizable mixture of cassava peel and caged

    African Journals Online (AJOL)

    Toluwande

    2011-09-05

    Sep 5, 2011 ... component of farm animal feed has been documented [8, 9]. Therefore, this investigation was carried out to study the response of broiler chicken to fermented mixture of cassava peel and caged layers' manure (obtained as farm residue or waste) and fed as a component of energy source in the feed.

  3. variations in dimensions and shape of thoracic cage with aging

    African Journals Online (AJOL)

    ABSTRACT. The thoracic cage variations in dimensions and proportions are influenced by age, sex and race. The objective of the present review was to describe the age related changes occurring in thoracic wall and its influence on the pattern of respiration in infants, adult and elderly. We had systematically reviewed, ...

  4. Clathrates-An Exploration of the Chemistry of Caged Compounds

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 9; Issue 7. Clathrates – An Exploration of the Chemistry of Caged Compounds. Srivathsa Vaidya. General Article ... Author Affiliations. Srivathsa Vaidya1. 64400 Freret Street Department of Chemistry Tulane University New Orleans, LA 70118 USA ...

  5. Rotational dynamics of propylene inside Na-Y zeolite cages

    Indian Academy of Sciences (India)

    molecules etc. Several such dependences have been under investigation [2]. We have in particular been investigating the diffusivities of hydrocarbons in Na-Y ze- olitic cages. In this context we had earlier reported the translational diffusivities of propane, acetylene and 1,3-butadiene in Na-Y zeolite [3–5]. The translational.

  6. FANTOM5 CAGE profiles of human and mouse samples

    NARCIS (Netherlands)

    Noguchi, Shuhei; Arakawa, Takahiro; Fukuda, Shiro; Furuno, Masaaki; Hasegawa, Akira; Hori, Fumi; Ishikawa-Kato, Sachi; Kaida, Kaoru; Kaiho, Ai; Kanamori-Katayama, Mutsumi; Kawashima, Tsugumi; Kojima, Miki; Kubosaki, Atsutaka; Manabe, Ri-ichiroh; Murata, Mitsuyoshi; Nagao-Sato, Sayaka; Nakazato, Kenichi; Ninomiya, Noriko; Nishiyori-Sueki, Hiromi; Noma, Shohei; Saijyo, Eri; Saka, Akiko; Sakai, Mizuho; Simon, Christophe; Suzuki, Naoko; Tagami, Michihira; Watanabe, Shoko; Yoshida, Shigehiro; Arner, Peter; Axton, Richard A; Babina, Magda; Baillie, J Kenneth; Barnett, Timothy C; Beckhouse, Anthony G; Blumenthal, Antje; Bodega, Beatrice; Bonetti, Alessandro; Briggs, James; Brombacher, Frank; Carlisle, Ailsa J; Clevers, Hans C; Davis, Carrie A; Detmar, Michael; Dohi, Taeko; Edge, Albert S B; Edinger, Matthias; Ehrlund, Anna; Ekwall, Karl; Endoh, Mitsuhiro; Enomoto, Hideki; Eslami, Afsaneh; Fagiolini, Michela; Fairbairn, Lynsey; Farach-Carson, Mary C; Faulkner, Geoffrey J; Ferrai, Carmelo; Fisher, Malcolm E; Forrester, Lesley M; Fujita, Rie; Furusawa, Jun-ichi; Geijtenbeek, Teunis B; Gingeras, Thomas; Goldowitz, Daniel; Guhl, Sven; Guler, Reto; Gustincich, Stefano; Ha, Thomas J; Hamaguchi, Masahide; Hara, Mitsuko; Hasegawa, Yuki; Herlyn, Meenhard; Heutink, Peter; Hitchens, Kelly J; Hume, David A; Ikawa, Tomokatsu; Ishizu, Yuri; Kai, Chieko; Kawamoto, Hiroshi; Kawamura, Yuki I; Kempfle, Judith S; Kenna, Tony J; Kere, Juha; Khachigian, Levon M; Kitamura, Toshio; Klein, Sarah; Klinken, S Peter; Knox, Alan J; Kojima, Soichi; Koseki, Haruhiko; Koyasu, Shigeo; Lee, Weonju; Lennartsson, Andreas; Mackay-Sim, Alan; Mejhert, Niklas; Mizuno, Yosuke; Morikawa, Hiromasa; Morimoto, Mitsuru; Moro, Kazuyo; Morris, Kelly J; Motohashi, Hozumi; Mummery, Christine L; Nakachi, Yutaka; Nakahara, Fumio; Nakamura, Toshiyuki; Nakamura, Yukio; Nozaki, Tadasuke; Ogishima, Soichi; Ohkura, Naganari; Ohno, Hiroshi; Ohshima, Mitsuhiro; Okada-Hatakeyama, Mariko; Okazaki, Yasushi; Orlando, Valerio; Ovchinnikov, Dmitry A; Passier, Robert; Patrikakis, Margaret; Pombo, Ana; Pradhan-Bhatt, Swati; Qin, Xian-Yang; Rehli, Michael; Rizzu, Patrizia; Roy, Sugata; Sajantila, Antti; Sakaguchi, Shimon; Sato, Hiroki; Satoh, Hironori; Savvi, Suzana; Saxena, Alka; Schmidl, Christian; Schneider, Claudio; Schulze-Tanzil, Gundula G; Schwegmann, Anita; Sheng, Guojun; Shin, Jay W; Sugiyama, Daisuke; Sugiyama, Takaaki; Summers, Kim M; Takahashi, Naoko; Takai, Jun; Tanaka, Hiroshi; Tatsukawa, Hideki; Tomoiu, Andru; Toyoda, Hiroo; van de Wetering, Marc; van den Berg, Linda M; Verardo, Roberto; Vijayan, Dipti; Wells, Christine A; Winteringham, Louise N; Wolvetang, Ernst; Yamaguchi, Yoko; Yamamoto, Masayuki; Yanagi-Mizuochi, Chiyo; Yoneda, Misako; Yonekura, Yohei; Zhang, Peter G; Zucchelli, Silvia; Abugessaisa, Imad; Arner, Erik; Harshbarger, Jayson; Kondo, Atsushi; Lassmann, Timo; Lizio, Marina; Sahin, Serkan; Sengstag, Thierry; Severin, Jessica; Shimoji, Hisashi; Suzuki, Masanori; Suzuki, Harukazu; Kawai, Jun; Kondo, Naoto; Itoh, Masayoshi; Daub, Carsten O; Kasukawa, Takeya; Kawaji, Hideya; Carninci, Piero; Forrest, Alistair R R; Hayashizaki, Yoshihide

    2017-01-01

    In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expression) coupled with single-molecule sequencing. Approximately three thousands of samples,

  7. Caged ceramide 1-phosphate analogues: synthesis and properties.

    Science.gov (United States)

    Lankalapalli, Ravi S; Ouro, Alberto; Arana, Lide; Gómez-Muñoz, Antonio; Bittman, Robert

    2009-11-20

    Sphingolipid phosphate analogues bearing 7-(diethylamino)coumarin (DECM) and 4-bromo-5-hydroxy-2-nitrobenzhydryl (BHNB) groups in a photolabile ester bond were synthesized. The ability of the "caged" ceramide 1-phosphate analogues to release the bioactive parent molecule upon irradiation at 400-500 nm was demonstrated by stimulation of macrophage cell proliferation.

  8. Thoracic cage injury imaging in rugby players | de Villiers | SA ...

    African Journals Online (AJOL)

    Rugby players often sustain high-impact collisions and are therefore at risk of significant traumatic thoracic injuries. Injury to the thoracic cage may be associated with potentially life-threatening sequelae. Player management is often based on the accuracy of the imaging report. The author suggests a combination of ...

  9. Business plan Tilapia cage farming in Tete Zambezi Valley, Mozambique

    NARCIS (Netherlands)

    Meer, van der Magnus; Brouwer, Herman

    2015-01-01

    Tete province offers great opportunities for cage farming of tilapia in Lake Cahora Bassa. The climate and water quality are favourable for fish production, and the fast economic developments in the region will facilitate fish sales. In Tete tilapia (pende) is highly valued food. Major markets for

  10. Cages Based on the Carbon-Carbon Composites

    Czech Academy of Sciences Publication Activity Database

    Sochor, M.; Balík, Karel; Tichý, P.; Vtípil, J.; Suchý, Tomáš; Sedláček, R.; Kolář, František; Černý, Martin; Beneš, J.; Hulejová, H.; Pešáková, V.

    12(132) (2003), s. 49-57 ISSN 1212-1576 R&D Projects: GA ČR GA106/00/1407 Institutional research plan: CEZ:AV0Z3046908 Keywords : carbon-carbon composites * cage * spine treatment Subject RIV: JH - Ceramics, Fire-Resistant Materials and Glass

  11. EFFECTS OF CAGING DENSITY ON PITUITARY AND TESTICLE RELATED RESPONSES

    Science.gov (United States)

    Effects of caging density on pituitary and testicle related responses A significant negative correlation between the incidence of testicular interstitial cell tumors (ICT) and of pituitary tumors (PT) in control male F344 rats is reported associated with the number of ani...

  12. Microbial control of caged population of Zonocerus variegatus using ...

    African Journals Online (AJOL)

    Microbial control of caged populations of Zonocerus variegatus was carried out using indigenous fungal entomopathogens isolated from the grasshopper's cadaver. Bioassay response indicated a dose-dependent mortality coupled with drastic reduction in food consumption among spores infected grasshoppers. Lethal time ...

  13. FANTOM5 CAGE profiles of human and mouse samples

    KAUST Repository

    Noguchi, Shuhei

    2017-08-29

    In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expression) coupled with single-molecule sequencing. Approximately three thousands of samples, consisting of a variety of primary cells, tissues, cell lines, and time series samples during cell activation and development, were subjected to a uniform pipeline of CAGE data production. The analysis pipeline started by measuring RNA extracts to assess their quality, and continued to CAGE library production by using a robotic or a manual workflow, single molecule sequencing, and computational processing to generate frequencies of transcription initiation. Resulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells. Non-overlapping peaks over the CAGE profiles, approximately 200,000 and 150,000 peaks for the human and mouse genomes, were identified and annotated to provide precise location of known promoters as well as novel ones, and to quantify their activities.

  14. Sex effect in mutual olfactory relationships of individually caged rabbits

    Directory of Open Access Journals (Sweden)

    Alessandro Finzi

    2015-12-01

    Full Text Available To assess the sex influence on sniffing behavior of rabbits, sets of three rabbits each were located for seven days in contiguous cages divided by a metal wall with holes that prevented the neighboring rabbits to see each other. A buck was located in the central cage, with a doe at each side. Rabbit behavior was video recorded to observe animals sniffing with the muzzle near the wall. The bucks displayed an olfactory preference towards one of the two does, which decreased in few days. The significance was p  0.05. The interest of bucks towards the does was also characterized by a frenetic scratching of the separation wall, contemporary with intense sniffing, displayed only for the first 35 min of the first day. The sniffing behavior of does at the central cage housing the male was not so marked as in bucks, and it progressively changed across the trial (p < 0.01. In conclusion, rabbits establish a transitory sex-oriented olfactory relationship with the conspecifics housed in contiguous cages, which looks no longer necessary once the rabbits have recognized each other.

  15. Mooring Design Selection of Aquaculture Cage for Indonesian Ocean

    Science.gov (United States)

    Mulyadi, Y.; Syahroni, N.; Sambodho, K.; Zikra, M.; Wahyudi; Adia, H. B. P.

    2018-03-01

    Fish production is important for the economy in fishing community and for ensuring food security. Climate change will lead a threat to fish productivity. Therefore, a solution offered is to cultivate certain fish, especially those with high economic value by using offshore aquaculture technology. A Sea Station cage is one of the offshore aquaculture cage model that has been used in some locations. As a floating structure, the Sea Station cage need a mooring system to maintain its position. This paper presents the selection analysis of the mooring system designs of the Sea Station cage model that it is suitable with Indonesia Ocean. There are 3 mooring configurations that are linear array, rectangular array, and 4 points mooring type. The nylon mooring rope type has been selected to be used on the 3 mooring configurations and the rope has a diameter of 104 mm with a breaking force of 2.3 MN. Based on results from comparing the 3 mooring configurations, the best mooring configuration is linear array with the tension on the rope of 217 KN and has the safety factor of 0.2 based on DNVGL OS-E301

  16. power generation and control of a self excited squirrel cage

    African Journals Online (AJOL)

    HOD

    The self-excited squirrel cage induction generator (SEIG) is frequently considered as the most economical solution for powering customers isolated from the utility grid by wind energy because it derives its excitation from its own output terminal and neither an exciter nor voltage regulator is required. Its major drawbacks ...

  17. Assessment of the Usability of the Workbench Faraday Cage Method

    DEFF Research Database (Denmark)

    Sørensen, Morten; Franek, Ondrej; Christensen, Søren K.

    2011-01-01

    The workbench Faraday Cage method (WBFC) is a time efficient module pre-compliance test regarding radiated emission. This work investigates the method’s usability and credibility and concludes that for this particular case the WBFC perform a tolerable compliance test for frequencies below 360 MHz...

  18. Complex susceptibility of the cage model of polar liquids

    CERN Document Server

    Coffey, W T; Kalmykov, Yu P; Titov, S V

    2003-01-01

    The Langevin equations of motion of the cage model of polar liquids originally proposed by Hill (1963 Proc. Phys. Soc. 82 723) are solved for the first time for the particular case of rotation about a fixed axis, using a newly developed matrix continued fraction method. It is shown that the cage model predicts both the low-frequency Debye relaxation and a pronounced high-frequency (Poley) absorption peak in the far-infrared (FIR) region. The similarity of the equations of motion of the cage model to the equations which arise in the problem of generalizing the Onsager model of polar fluids to include a time-varying applied field suggests that the FIR (Poley) absorption may have its origins in the combined influence of molecular inertia and the torque due to the reaction field in the frequency-dependent version of the Onsager model. The complex susceptibility yielded by the cage model is shown to be in good agreement with experimental data on CH sub 3 Cl that were taken as a typical example. Moreover, a simple ...

  19. Mice Do Not Habituate to Metabolism Cage Housing

    DEFF Research Database (Denmark)

    Kalliokoski, Otto; Jacobsen, Kirsten Rosenmaj; Darusman, Huda Shalahudin

    2013-01-01

    The metabolism cage is a barren, non-enriched, environment, combining a number of recognized environmental stressors. We investigated the ability of male BALB/c mice to acclimatize to this form of housing. For three weeks markers of acute and oxidative stress, as well as clinical signs of abnorma...

  20. Radiological outcomes of static vs expandable titanium cages after corpectomy: a retrospective cohort analysis of subsidence.

    Science.gov (United States)

    Lau, Darryl; Song, Yeohan; Guan, Zhe; La Marca, Frank; Park, Paul

    2013-04-01

    Mesh cages have commonly been used for reconstruction after corpectomy. Recently, expandable cages have become a popular alternative. Regardless of cage type, subsidence is a concern following cage placement. To assess whether subsidence rates differ between static and expandable cages, and identify independent risk factors for subsidence and extent of subsidence when present. A consecutive population of patients who underwent corpectomy between 2006 and 2009 was identified. Subsidence was assessed via x-ray at 1-month and 1-year follow-ups. In addition to cage type, demographic, medical, and cage-related covariates were recorded. Multivariate models were used to assess independent associations with rate, odds, and extent of subsidence. Of 91 patients, 44.0% had expandable cages and 56.0% had static cages. One-month subsidence rate was 36.3%, and the 1-year subsidence rate was 51.6%. Expandable cages were independently associated with higher rates and odds of subsidence in comparison with static cages. Infection, trauma, and footplate-to-vertebral body endplate ratio of less than 0.5 were independent risk factors for subsidence. The presence of prongs on cages and posterior fusion 2 or more levels above and below corpectomy level had lower rates and odds of subsidence. Infection and cage placement in the thoracic or lumbar region had greater extent of subsidence when subsidence was present. Expandable cages had higher rates and risk of subsidence in comparison with static cages. When subsidence was present, expandable cages had greater magnitudes of subsidence. Other factors including footplate-to-vertebral body endplate ratio, prongs, extent of supplemental posterior fusion, spinal region, and diagnosis also impacted subsidence.

  1. Is a standalone inertial measurement unit accurate and precise enough for quantification of movement symmetry in the horse?

    DEFF Research Database (Denmark)

    Brighton, Charlotte; Olsen, Emil; Pfau, Thilo

    2015-01-01

    Standalone ‘low-cost’ inertial measurement units (IMUs) could facilitate large-scale studies into establishing minimal important differences (MID) for orthopaedic deficits (lameness) in horses. We investigated accuracy and limits of agreement (LoA) after correction of magnitude-dependent differen......Standalone ‘low-cost’ inertial measurement units (IMUs) could facilitate large-scale studies into establishing minimal important differences (MID) for orthopaedic deficits (lameness) in horses. We investigated accuracy and limits of agreement (LoA) after correction of magnitude......-dependent differences of a standalone 6 degree-of-freedom IMU compared with an established IMU-based gait analysis system (MTx) in six horses for two anatomical landmarks (sacrum and sternum). Established symmetry measures were calculated from vertical displacement: symmetry index (SI), difference between minima (Min......, whereas MinDiff and MaxDiff values are less favourable. Future studies should investigate specific calibration and processing algorithms further improving standalone IMU performance....

  2. Corpectomy cage subsidence with rectangular versus round endcaps.

    Science.gov (United States)

    Deukmedjian, Armen R; Manwaring, Jotham; Le, Tien V; Turner, Alexander W L; Uribe, Juan S

    2014-09-01

    Corpectomy cages with rectangular endcaps utilize the stronger peripheral part of the endplate, potentially decreasing subsidence risk. The authors evaluated cage subsidence during cyclic biomechanical testing, comparing rectangular versus round endcaps. Fourteen cadaveric spinal segments (T12-L2) were dissected and potted at T12 and L2, then assigned to a rectangular (n=7) or round (n=7) endcap group. An L1 corpectomy was performed and under uniform conditions a cage/plate construct was cyclically tested in a servo-hydraulic frame with increasing load magnitude. Testing was terminated if the test machine actuator displacement exceeded 6mm, or the specimen completed cyclic loading at 2400 N. Number of cycles, compressive force and force-cycles product at test completion were all greater in the rectangular endcap group compared with the round endcap group (cycles: 3027 versus 2092 cycles; force: 1943 N versus 1533 N; force-cycles product: 6162kN·cycles versus 3973 kN·cycles), however these differences were not statistically significant (p ⩾ 0.076). After normalizing for individual specimen bone mineral density, the same measures increased to a greater extent with the rectangular endcaps (cycles: 3014 versus 1855 cycles; force: 1944 N versus 1444 N; force-cycles product: 6040 kN·cycles versus 2980 kN·cycles), and all differences were significant (p⩽0.030). The rectangular endcap expandable corpectomy cage displayed increased resistance to subsidence over the round endcap cage under cyclic loading as demonstrated by the larger number of cycles, maximum load and force-cycles product at test completion. This suggests rectangular endcaps will be less susceptible to subsidence than the round endcap design. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Social communication in mice--are there optimal cage conditions?

    Directory of Open Access Journals (Sweden)

    Allain-Thibeault Ferhat

    Full Text Available Social communication is heavily affected in patients with neuropsychiatric disorders. Accordingly, mouse models designed to study the mechanisms leading to these disorders are tested for this phenotypic trait. Test conditions vary between different models, and the effect of these test conditions on the quantity and quality of social interactions and ultrasonic communication is unknown. The present study examines to which extent the habituation time to the test cage as well as the shape/size of the cage influence social communication in freely interacting mice. We tested 8 pairs of male mice in free dyadic social interactions, with two habituation times (20 min and 30 min and three cage formats (rectangle, round, square. We tested the effect of these conditions on the different types of social contacts, approach-escape sequences, follow behavior, and the time each animal spent in the vision field of the other one, as well as on the emission of ultrasonic vocalizations and their contexts of emission. We provide for the first time an integrated analysis of the social interaction behavior and ultrasonic vocalizations. Surprisingly, we did not highlight any significant effect of habituation time and cage shape/size on the behavioral events examined. There was only a slight increase of social interactions with the longer habituation time in the round cage. Remarkably, we also showed that vocalizations were emitted during specific behavioral sequences especially during close contact or approach behaviors. The present study provides a protocol reliably eliciting social contacts and ultrasonic vocalizations in adult male mice. This protocol is therefore well adapted for standardized investigation of social interactions in mouse models of neuropsychiatric disorders.

  4. 48 CFR 252.204-7001 - Commercial and Government Entity (CAGE) code reporting.

    Science.gov (United States)

    2010-10-01

    ... Entity (CAGE) code reporting. 252.204-7001 Section 252.204-7001 Federal Acquisition Regulations System... Entity (CAGE) Code Reporting (AUG 1999) (a) The offeror is requested to enter its CAGE code on its offer... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.204-7001 Commercial and Government Entity...

  5. 30 CFR 75.1403-3 - Criteria-Drum clutch; cage construction.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Criteria-Drum clutch; cage construction. 75... § 75.1403-3 Criteria—Drum clutch; cage construction. (a) The clutch of a free-drum on a personnel hoist... withdrawal of the clutch. (b) Cages used for hoisting persons should be constructed with the sides enclosed...

  6. Can forced hot air quickly dry feces on transport cage flooring and eliminate campylobacter before cage re-use?

    Science.gov (United States)

    Allowing feces left on transport coops to dry is an effective way to reduce numbers of viable Campylobacter left by positive flocks. The problem with this approach is that poultry processors do not have the time, space or resources to maintain several times the minimum number of transport cages that...

  7. Subsidence of Cylindrical Cage (AMSLU™ Cage) : Postoperative 1 Year Follow-up of the Cervical Anterior Interbody Fusion

    Science.gov (United States)

    Joung, Young Il; Ko, Yong; Yi, Hyeong Joong; Lee, Seung Ku

    2007-01-01

    Objective There are numerous reports on the primary stabilizing effects of the different cervical cages for cervical radiculopathy. But, little is known about the subsidence which may be clinical problem postoperatively. The goal of this study is to evaluate subsidence of cage and investigate the correlation between radiologic subsidence and clinical outcome. Methods To assess possible subsidence, the authors investigated clinical and radiological results of the one-hundred patients who underwent anterior cervical fusion by using AMSLU™ cage during the period between January 2003 and June 2005. Preoperative and postoperative lateral radiographs were measured for height of intervertebral disc space where cages were placed. Intervertebral disc space was measured by dividing the sum of anterior, posterior, and midpoint interbody distance by 3. Follow-up time was 6 to 12 months. Subsidence was defined as any change in at least one of our parameters of at least 3 mm. Results Subsidence was found in 22 patients (22%). The mean value of subsidence was 2.21 mm, and mean subsidence rate was 22%. There were no cases of the clinical status deterioration during the follow-up period. No posterior or anterior migration was observed. Conclusion The phenomenon of subsidence is seen in substantial number of patients. Nevertheless, clinical and radiological results of the surgery were favorable. An excessive subsidence may result in hardware failure. Endplate preservation may enables us to control subsidence and reduce the number of complications. PMID:19096571

  8. Comparison Between Acrylic Cage and Polyetheretherketone (PEEK) Cage in Single-level Anterior Cervical Discectomy and Fusion: A Randomized Clinical Trial.

    Science.gov (United States)

    Farrokhi, Majid R; Nikoo, Zahra; Gholami, Mehrnaz; Hosseini, Khadijeh

    2017-02-01

    Prospective, single-blind randomized-controlled clinical study. To compare polyetheretherketone (PEEK) cage with a novel Acrylic cage to find out which fusion cage yielded better clinical outcomes following single-level anterior cervical discectomy and fusion (ACDF). ACDF is considered a standard neurosurgical treatment for degenerative diseases of cervical intervertebral disks. There are many options, including bone grafts, bone cement, and spacers made of titanium, carbon fiber, and synthetic materials, used to restore physiological disk height and enhance spinal fusion, but the ideal device, which would provide immediate structural support and subsequent osteointegration and stability, has not been identified yet. To overcome this, we designed a new, inexpensive Acrylic cage. A total of 64 patients were eligible to participate and were randomly allocated to undergo ACDF either with Acrylic interbody fusion cage filled with bone substitute (n=32) or PEEK cage (n=32). Nurick's grading was used for quantifying the neurological deficit. Clinical and radiologic outcome was assessed preoperatively, immediately after surgery, and subsequently at 2, 6, and 12 months of follow-up using Odom's criteria and dynamic radiographs (flexion-extension) and computed tomography scans, respectively. There was a statistically significant improvement in the clinical outcomes of the Acrylic cage group compared with the PEEK cage group (mean difference: -0.438; 95% confidence interval, -0.807 to -0.068; P=0.016). There was a statistically significant difference in disk space height increase between the 2 groups at the 6- and 12-month follow-up. The Acrylic cage achieved higher fusion rate (good fusion) than the PEEK cage (96.9% vs. 93.8%). Intervertebral angle demonstrated a significant difference among the 2 treated groups throughout the follow-up period. This study suggests that the use of Acrylic cage is associated with good clinical and radiologic outcomes and it can be therefore a

  9. Effects of single caging and cage size on behavior and stress level of domestic neutered cats housed in an animal shelter.

    Science.gov (United States)

    Uetake, Katsuji; Goto, Akihiro; Koyama, Rumi; Kikuchi, Rieko; Tanaka, Toshio

    2013-03-01

    Cats need a minimum amount of space even in animal shelters. In this study the effects of single caging and cage size on the behavior and stress level of domestic cats were investigated. Six neutered cats (2-15 years old) that had been housed in a group for at least 7 months were moved to three kinds of single cages (small, medium and large) by rotation on a Latin square design. They experienced each cage size for 6 days. Cats could use vertical dimensions when housed in a group room and the large cage. Behavioral observation was conducted for 3 h in the evening, and stress levels were assessed by urine cortisol-to-creatinine ratios. The amounts (estimated proportions) of time spent in locomotion and social/solitary play were lower even in large cages than in group housing (both P housed singly (P = 0.104). The urine cortisol-to-creatinine ratios of singly housed cats tended to be higher than that of group-housed cats (P = 0.086). The results indicate that cats become less active when they are housed singly in cages regardless of the cage size. Cats seem to feel no undue stress even in small cages if the stay is short. © 2012 The Authors. Animal Science Journal © 2012 Japanese Society of Animal Science.

  10. Complete cage migration/subsidence into the adjacent vertebral body after posterior lumbar interbody fusion.

    Science.gov (United States)

    Corniola, Marco V; Jägersberg, Max; Stienen, Martin N; Gautschi, Oliver P

    2015-03-01

    A variety of implant-related short and long-term complications after lumbar fusion surgery are recognized. Mid to long-term complications due to cage migration and/or cage subsidence are less frequently reported. Here, we report a patient with a complete cage migration into the superior adjacent vertebral body almost 20 years after the initial posterior lumbar interbody fusion procedure. In this patient, the cage migration/subsidence was clinically silent, but a selective decompression for adjacent segment degenerative lumbar spinal stenosis was performed. We discuss the risk factors for cage migration/subsidence in view of the current literature. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. A Simple Sizing Algorithm for Stand-Alone PV/Wind/Battery Hybrid Microgrids

    Directory of Open Access Journals (Sweden)

    Jing Li

    2012-12-01

    Full Text Available In this paper, we develop a simple algorithm to determine the required number of generating units of wind-turbine generator and photovoltaic array, and the associated storage capacity for stand-alone hybrid microgrid. The algorithm is based on the observation that the state of charge of battery should be periodically invariant. The optimal sizing of hybrid microgrid is given in the sense that the life cycle cost of system is minimized while the given load power demand can be satisfied without load rejection. We also report a case study to show the efficacy of the developed algorithm.

  12. Stand-alone and Interdisciplinary Course Design for Engineering Education for Sustainable Development

    DEFF Research Database (Denmark)

    Arsat, M.; Holgaard, Jette Egelund; de Graaff, Erik

    In order to embed ESD in the EE curriculum, several approaches has been introduced and practiced in higher education institutions. One of the approaches is to introduce a new ESD course as an add-on to the existing curriculum being either compulsory or elective and either designed for a single...... and reported examples of other ESD courses of the same kind. The presented conceptual framework is put to practice, characterising the AAU course as a stand-alone interdisciplinary course with a consensual approach. The conclusion is that the conceptual framework can provide an awareness of the design features...

  13. Optimum Availability of Standalone Photovoltaic Power Systems for Remote Housing Electrification

    Directory of Open Access Journals (Sweden)

    Tamer Khatib

    2014-01-01

    Full Text Available The availability of PV systems is discussed to determine the optimum availability at which standalone PV systems must be designed. Optimization methods and PV systems software, such as HOMER and PV.MY, were used for this purpose. Six PV systems with six availability levels were analyzed, in terms of wasted energy, cost of energy, battery usage, and power shortages, using real meteorological data. Results show that PV systems with 99% availability are recommended, because of their high reliability and favorably wasted energy.

  14. Evaluating a Pre-session Exercise in a Standalone Information Literacy Class

    Directory of Open Access Journals (Sweden)

    Joseph E. Goetz

    2015-12-01

    Full Text Available In this study, researchers evaluate a homework exercise assigned before a standalone information literacy session. Students in a Master of Education program completed a worksheet using the ERIC database thesaurus. The researchers conducted pre- and posttests within a single library session to assess student learning, using a control group for comparison. The treatment group did not demonstrate better thesaurus skills than students who had regular library instruction alone, but results pointed the way to targeted improvements of pre-session learning materials. This approach could inform other information literacy homework applications such as flipping the classroom.

  15. Information systems for the materials management department: stand-alone and enterprise resource planning systems.

    Science.gov (United States)

    2005-03-01

    Materials management information systems (MMISs) incorporate information tools that hospitals can use to automate certain business processes, increase staff compliance with these processes, and identify opportunities for cost savings. Recently, there has been a push by hospital administration to purchase enterprise resource planning (ERP) systems, information systems that promise to integrate many more facets of healthcare business. We offer this article to help materials managers, administrators, and others involved with information system selection understand the changes that have taken place in materials management information systems, decide whether they need a new system and, if so, whether a stand-alone MMIS or an ERP system will be the best choice.

  16. Incidence and impact of implant subsidence after stand-alone lateral lumbar interbody fusion.

    Science.gov (United States)

    Bocahut, N; Audureau, E; Poignard, A; Delambre, J; Queinnec, S; Flouzat Lachaniette, C-H; Allain, J

    2017-12-30

    Few data are available on the occurrence after stand-alone lateral lumbar interbody fusion (LLIF) of implant subsidence, whose definition and incidence vary across studies. The primary objective of this work was to determine the incidence of subsidence 1 year postoperatively, using an original measurement method, whose validity was first assessed. The secondary objective was to assess the clinical impact of subsidence. Implant subsidence after stand-alone LLIF is a common complication that can adversely affect clinical outcomes. Of 69 included patients who underwent stand-alone LLIF, 67 (97%) were re-evaluated at least 1 year later. Furthermore, 63 (91%) patients had two available computed tomography (CT) scans for assessing subsidence, one performed immediately after surgery and the other 1 year later. Reproducibility of the original measurement method was assessed in a preliminary study. Subsidence was defined as at least 4mm loss of fused space height. The incidence of subsidence was 32% (20 patients). Subsidence was global in 7 (11%) patients and partial in 13 (21%) patients. Mean loss of height was 5.5±1.5mm. Subsidence predominated anteriorly in 50% of cases. The lordotic curvature of the fused segment was altered in 50% of patients, by a mean of 8°±3°. Fusion was achieved in 67/69 (97%) patients. The Oswestry score and visual analogue scale scores for low-back and nerve-root pain were significantly improved after 1 year in the overall population and in the groups with and without subsidence. Reproducibility of our measurement method was found to be excellent. Subsidence was common but without significant clinical effects after 1 year. Nevertheless, subsidence can be associated with pain and can result in loss of lumbar lordosis, which is a potential risk factor for degenerative disease of the adjacent segments. A score for predicting the risk of subsidence will now be developed by our group as a tool for improving patient selection to stand-alone LLIF

  17. Boost converter with combined control loop for a stand-alone photovoltaic battery charge system

    DEFF Research Database (Denmark)

    Mira Albert, Maria del Carmen; Knott, Arnold; Thomsen, Ole Cornelius

    2013-01-01

    frequency avoids perturbations in the load being propagated to the photovoltaic panel and thus deviating the operating point. Linearization of the photovoltaic panel and converter state-space modeling is performed. In order to achieve stable operation under all operating conditions, the photovoltaic panel......The converter control scheme plays an important role in the performance of maximum power point tracking (MPPT) algorithms. In this paper, an input voltage control with double loop for a stand-alone photovoltaic system is designed and tested. The inner current control loop with high crossover...

  18. Smart integrated energy monitoring and management system for standalone photovoltaic systems

    Science.gov (United States)

    Abou-Elnour, Ali; Murad, Fahd S.; Al-Tayasna, Ibrahim S.; Abo-Elnor, Ossama

    2013-04-01

    In the present work, a computer based smart integrated energy monitoring and management system for standalone photovoltaic systems is designed and implemented. Monitoring, controlling, and recording features are fully obtained in the present system using an efficient programming environment. All required data are monitored as real-time data therefore the system status is continuously evaluated and decisions are made to take immediate actions. The energy consumption of different appliances are automatically controlled and optimized using a hierarchical self adaptive algorithm based on input data and real-time information provided by the system sensors. The proposed system is successfully implemented for photovoltaic modules under realistic operating conditions.

  19. Cathodic cage nitriding of samples with different dimensions

    International Nuclear Information System (INIS)

    Sousa, R.R.M. de; Araujo, F.O. de; Ribeiro, K.J.B.; Mendes, M.W.D.; Costa, J.A.P. da; Alves, C.

    2007-01-01

    A series of AISI 1020 steel cylindrical samples with different heights were simultaneously nitrided in cathodic cage plasma nitriding. In this technique, the samples are placed under a floating potential inside a cage in which the cathodic potential is applied. A systematic study of the nitriding temperature variation effects was carried out in order to evaluate the efficiency of such a technique over the uniformity of the formed layers. The samples were characterized by optical microscopy, X-ray diffraction and microhardness measurement. The results were compared with those ones obtained in the ionic nitriding, and was verified that the samples nitrided by this conventional technique presents less uniformity than the ones treated through this new technique

  20. Cathodic cage nitriding of samples with different dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Sousa, R.R.M. de [Centro Federal de Educacao Tecnologica do Piaui, Department of Mechanical, Teresina, PI (Brazil); Araujo, F.O. de [Universidade Federal Rural do Semi-Arido, Mossoro, RN (Brazil); Ribeiro, K.J.B.; Mendes, M.W.D. [Labplasma, Departamento de Fisica-UFRN, Campus Universitario, 59072-970 Natal, RN (Brazil); Costa, J.A.P. da [Departamento de Fisica-UFC, Fortaleza, CE (Brazil); Alves, C. [Labplasma, Departamento de Fisica-UFRN, Campus Universitario, 59072-970 Natal, RN (Brazil)], E-mail: alvesjr@pesquisador.cnpq.br

    2007-09-15

    A series of AISI 1020 steel cylindrical samples with different heights were simultaneously nitrided in cathodic cage plasma nitriding. In this technique, the samples are placed under a floating potential inside a cage in which the cathodic potential is applied. A systematic study of the nitriding temperature variation effects was carried out in order to evaluate the efficiency of such a technique over the uniformity of the formed layers. The samples were characterized by optical microscopy, X-ray diffraction and microhardness measurement. The results were compared with those ones obtained in the ionic nitriding, and was verified that the samples nitrided by this conventional technique presents less uniformity than the ones treated through this new technique.

  1. The BetaCage: Ultrasensitive Screener for Radioactive Backgrounds

    Science.gov (United States)

    Thompson, Michael; BetaCage Collaboration

    2017-09-01

    Rare event searches, such as dark matter detection and neutrinoless double beta decay, require screening of materials for backgrounds such as beta emission and alpha decaying isotopes. The BetaCage is a proposed ultra-sensitive time-projection chamber to screen for alpha-emitting and low energy beta-emitting (10-200 keV) contaminants. The expected sensitivity is 0.1 beta particles (perkeV -m2 - day) and 0.1 alpha particles (perm2 - day) , where the former will be limited by Compton scattering of external photons in the screening samples and the latter is expected to be signal-limited. The prototype BetaCage under commissioning at South Dakota School of Mines & Technology is filled with P10 gas (10% methane, 90% argon) in place of neon and is 40×40×20 cm in size. Details on design, construction and characterization will be presented.

  2. Cage structure application in photoelectric experiment and teaching

    Science.gov (United States)

    Li, Xiufang; Zhao, Peng; Liu, Shugang

    2017-08-01

    A new type of photoelectric system structure, cage system, is introduced. This kind of coaxial modularized structure not only can be quickly assembled, but also can easily realize different purposes by substituting elements in the system. In addition, it's light and portable, which enable teachers to carry it to wherever suitable for teaching. In conclusion, this structure can improve teaching effect and stimulate student's interest in photoelectric courses.

  3. Pulsed EPR characterization of encapsulated atomic hydrogen in octasilsesquioxane cages.

    Science.gov (United States)

    Mitrikas, George

    2012-03-21

    Hydrogen atoms encapsulated in molecular cages are potential candidates for quantum computing applications. They provide the simplest two-spin system where the 1s electron spin, S = 1/2, is hyperfine-coupled to the proton nuclear spin, I = 1/2, with a large isotropic hyperfine coupling (A = 1420.40575 MHz for a free atom). While hydrogen atoms can be trapped in many matrices at cryogenic temperatures, it has been found that they are exceptionally stable in octasilsesquioxane cages even at room temperature [Sasamori et al., Science, 1994, 256, 1691]. Here we present a detailed spin-lattice and spin-spin relaxation study of atomic hydrogen encapsulated in Si(8)O(12)(OSiMe(2)H)(8) using X-band pulsed EPR spectroscopy. The spin-lattice relaxation times T(1) range between 1.2 s at 20 K and 41.8 μs at room temperature. The temperature dependence of the relaxation rate shows that for T 100 K a thermally activated process with activation energy E(a) = 753 K (523 cm(-1)) prevails. The phase memory time T(M) = 13.9 μs remains practically constant between 200 and 300 K and is determined by nuclear spin diffusion. At lower temperatures T(M) decreases by an order of magnitude and exhibits two minima at T = 140 K and T = 60 K. The temperature dependence of T(M) between 20 and 200 K is attributed to dynamic processes that average inequivalent hyperfine couplings, e.g. rotation of the methyl groups of the cage organic substituents. The hyperfine couplings of the encapsulated proton and the cage (29)Si nuclei are obtained through numerical simulations of field-swept FID-detected EPR spectra and HYSCORE experiments, respectively. The results are discussed in terms of existing phenomenological models based on the spherical harmonic oscillator and compared to those of endohedral fullerenes.

  4. Energy saving work of frequency controlled induction cage machine

    International Nuclear Information System (INIS)

    Gnacinski, P.

    2007-01-01

    Energy saving work, understood as lowering the supply voltage when load torque is much less than rated, is one way of reducing power losses in an induction cage machine working with a variable load. Reduction in power losses also affects the thermal properties of an induction machine because the energy saving work allows the temperature rise of the windings to decrease. Thanks to a lower temperature of the windings, the same load torque can be carried by a machine of less rated power. The ability of energy saving work to reduce the temperature of windings depends on the thermal properties of an induction machine, which are different in the case of a machine with foreign ventilation and its own ventilation. This paper deals with the thermal effect of energy saving work on a frequency controlled induction cage machine. A comparison of the properties of a machine with its own and outside ventilation is presented. The results of the investigations are shown for a 3 kW induction cage machine with the two previously mentioned ways of ventilation: one provided with a fan placed on a shaft and the other provided with a fan driven by an auxiliary motor

  5. Experience with titanium cages in anterior cervical discectomy and fusion

    International Nuclear Information System (INIS)

    Junaid, M.; Afsheen, A.; Bukhari, S.S.; Rashid, M.U.; Kalsoom, A.

    2016-01-01

    Background: Anterior cervical discectomy is a common procedure for treating patients for cervical disc prolapse. This study was conducted to study the surgical outcome and demographic characteristics of patients who were treated for anterior cervical disc prolapse. Methods: Study was conducted in the combined military hospital (CMH) Peshawar. Study interval was 3 years from 1st September, 2011 to 31st August, 2014. Total number of patients were 84. Males were 54 (64.28 percentage) and females were 30 (35.71 percentage). All the patients had undergone the procedure of anterior cervical discectomy and fusion with titanium cages (ACDF). All the patients had plain MRI cervical spine done for diagnosis of anterior cervical disc prolapse. Results: Total 84 patients were operated. In the patients who complained of brachialgia, 100 percentage improvement was seen after the operation. Three (3.5 percentage) of the patients, who presented with axial neck pain, continued to complain of pain and 2 (2.5 percentage) of the patients complained of pain at the donor site after the operation. One of the patient had dural tear which resulted in subcutaneous cerebrospinal fluid (CSF) accumulation and was treated conservatively with repeated aspiration. Fusion rate was 100 percentage with titanium cages used for fusion after anterior cervical discectomy. No complications were noted after the surgery at 1 year of interval. Conclusion: Results with titanium cages are expectedly good. Symptoms resolved and fusion rate was 100 percentage at 1 year follow up. (author)

  6. Feasibility and Optimal Design of a Stand-Alone Photovoltaic Energy System for the Orphanage

    Directory of Open Access Journals (Sweden)

    Vincent Anayochukwu Ani

    2014-01-01

    Full Text Available Access to electricity can have a positive psychological impact through a lessening of the sense of exclusion, and vulnerability often felt by the orphanages. This paper presented the simulation and optimization study of a stand-alone photovoltaic power system that produced the desired power needs of an orphanage. Solar resources for the design of the system were obtained from the National Aeronautics and Space Administration (NASA Surface Meteorology and Solar Energy website at a location of 6°51′N latitude and 7°35′E longitude, with annual average solar radiation of 4.92 kWh/m2/d. This study is based on modeling, simulation, and optimization of energy system in the orphanage. The patterns of load consumption within the orphanage were studied and suitably modeled for optimization. Hybrid Optimization Model for Electric Renewables (HOMER software was used to analyze and design the proposed stand-alone photovoltaic power system model. The model was designed to provide an optimal system configuration based on an hour-by-hour data for energy availability and demands. A detailed design, description, and expected performance of the system were presented in this paper.

  7. Coordination Control Strategy for AC/DC Hybrid Microgrids in Stand-Alone Mode

    Directory of Open Access Journals (Sweden)

    Dwi Riana Aryani

    2016-06-01

    Full Text Available Interest in DC microgrids is rapidly increasing along with the improvement of DC power technology because of its advantages. To support the integration process of DC microgrids with the existing AC utility grids, the form of hybrid AC/DC microgrids is considered for higher power conversion efficiency, lower component cost and better power quality. In the system, AC and DC portions are connected through interlink bidirectional AC/DC converters (IC with a proper control system and power management. In the stand-alone operation mode of AC/DC hybrid microgrids, the control of power injection through the IC is crucial in order to maintain the system security. This paper mainly deals with a coordination control strategy of IC and a battery energy storage system (BESS converter under stand-alone operation. A coordinated control strategy for the IC, which considers the state of charge (SOC level of BESS and the load shedding scheme as the last resort, is proposed to obtain better power sharing between AC and DC subgrids. The scheme will be tested with a hybrid AC/DC microgrid, using the tool of the PSCAD/EMTDC software.

  8. Fuzzy logic control of stand-alone photovoltaic system with battery storage

    Science.gov (United States)

    Lalouni, S.; Rekioua, D.; Rekioua, T.; Matagne, E.

    Photovoltaic energy has nowadays an increased importance in electrical power applications, since it is considered as an essentially inexhaustible and broadly available energy resource. However, the output power provided via the photovoltaic conversion process depends on solar irradiation and temperature. Therefore, to maximize the efficiency of the photovoltaic energy system, it is necessary to track the maximum power point of the PV array. The present paper proposes a maximum power point tracker (MPPT) method, based on fuzzy logic controller (FLC), applied to a stand-alone photovoltaic system. It uses a sampling measure of the PV array power and voltage then determines an optimal increment required to have the optimal operating voltage which permits maximum power tracking. This method carries high accuracy around the optimum point when compared to the conventional one. The stand-alone photovoltaic system used in this paper includes two bi-directional DC/DC converters and a lead-acid battery bank to overcome the scare periods. One converter works as an MPP tracker, while the other regulates the batteries state of charge and compensates the power deficit to provide a continuous delivery of energy to the load. The Obtained simulation results show the effectiveness of the proposed fuzzy logic controller.

  9. Standalone computer-aided detection compared to radiologists' performance for the detection of mammographic masses

    International Nuclear Information System (INIS)

    Hupse, Rianne; Samulski, Maurice; Imhof-Tas, Mechli W.; Karssemeijer, Nico; Lobbes, Marc; Boetes, Carla; Heeten, Ard den; Beijerinck, David; Pijnappel, Ruud

    2013-01-01

    We developed a computer-aided detection (CAD) system aimed at decision support for detection of malignant masses and architectural distortions in mammograms. The effect of this system on radiologists' performance depends strongly on its standalone performance. The purpose of this study was to compare the standalone performance of this CAD system to that of radiologists. In a retrospective study, nine certified screening radiologists and three residents read 200 digital screening mammograms without the use of CAD. Performances of the individual readers and of CAD were computed as the true-positive fraction (TPF) at a false-positive fraction of 0.05 and 0.2. Differences were analysed using an independent one-sample t-test. At a false-positive fraction of 0.05, the performance of CAD (TPF = 0.487) was similar to that of the certified screening radiologists (TPF = 0.518, P = 0.17). At a false-positive fraction of 0.2, CAD performance (TPF = 0.620) was significantly lower than the radiologist performance (TPF = 0.736, P <0.001). Compared to the residents, CAD performance was similar for all false-positive fractions. The sensitivity of CAD at a high specificity was comparable to that of human readers. These results show potential for CAD to be used as an independent reader in breast cancer screening. (orig.)

  10. International market assessment of stand-alone photovoltaic power systems for cottage industry applications

    Science.gov (United States)

    Philippi, T. M.

    1981-01-01

    The final result of an international assessment of the market for stand-alone photovoltaic systems in cottage industry applications is reported. Nonindustrialized countries without centrally planned economies were considered. Cottage industries were defined as small rural manufacturers, employing less than 50 people, producing consumer and simple products. The data to support this analysis were obtained from secondary and expert sources in the U.S. and in-country field investigations of the Philippines and Mexico. The near-term market for photovoltaics for rural cottage industry applications appears to be limited to demonstration projects and pilot programs, based on an in-depth study of the nature of cottage industry, its role in the rural economy, the electric energy requirements of cottage industry, and a financial analysis of stand-alone photovoltaic systems as compared to their most viable competitor, diesel driven generators. Photovoltaics are shown to be a better long-term option only for very low power requirements. Some of these uses would include clay mixers, grinders, centrifuges, lathes, power saws and lighting of a workshop.

  11. A sizing method for stand-alone PV installations with variable demand

    Energy Technology Data Exchange (ETDEWEB)

    Posadillo, R. [Grupo de Investigacion en Energias y Recursos Renovables, Dpto. de Fisica Aplicada, E.P.S., Universidad de Cordoba, Avda. Menendez Pidal s/n, 14004 Cordoba (Spain); Lopez Luque, R. [Grupo de Investigacion de Fisica Para las Energias y Recursos Renovables, Dpto. de Fisica Aplicada, Edificio C2 Campus de Rabanales, 14071 Cordoba (Spain)

    2008-05-15

    The practical applicability of the considerations made in a previous paper to characterize energy balances in stand-alone photovoltaic systems (SAPV) is presented. Given that energy balances were characterized based on monthly estimations, the method is appropriate for sizing installations with variable monthly demands and variable monthly panel tilt (for seasonal estimations). The method presented is original in that it is the only method proposed for this type of demand. The method is based on the rational utilization of daily solar radiation distribution functions. When exact mathematical expressions are not available, approximate empirical expressions can be used. The more precise the statistical characterization of the solar radiation on the receiver module, the more precise the sizing method given that the characterization will solely depend on the distribution function of the daily global irradiation on the tilted surface H{sub g{beta}}{sub i}. This method, like previous ones, uses the concept of loss of load probability (LLP) as a parameter to characterize system design and includes information on the standard deviation of this parameter ({sigma}{sub LLP}) as well as two new parameters: annual number of system failures (f) and the standard deviation of annual number of system failures ({sigma}{sub f}). This paper therefore provides an analytical method for evaluating and sizing stand-alone PV systems with variable monthly demand and panel inclination. The sizing method has also been applied in a practical manner. (author)

  12. Robust Power Management Control for Stand-Alone Hybrid Power Generation System

    International Nuclear Information System (INIS)

    Kamal, Elkhatib; Adouane, Lounis; Aitouche, Abdel; Mohammed, Walaa

    2017-01-01

    This paper presents a new robust fuzzy control of energy management strategy for the stand-alone hybrid power systems. It consists of two levels named centralized fuzzy supervisory control which generates the power references for each decentralized robust fuzzy control. Hybrid power systems comprises: a photovoltaic panel and wind turbine as renewable sources, a micro turbine generator and a battery storage system. The proposed control strategy is able to satisfy the load requirements based on a fuzzy supervisor controller and manage power flows between the different energy sources and the storage unit by respecting the state of charge and the variation of wind speed and irradiance. Centralized controller is designed based on If-Then fuzzy rules to manage and optimize the hybrid power system production by generating the reference power for photovoltaic panel and wind turbine. Decentralized controller is based on the Takagi-Sugeno fuzzy model and permits us to stabilize each photovoltaic panel and wind turbine in presence of disturbances and parametric uncertainties and to optimize the tracking reference which is given by the centralized controller level. The sufficient conditions stability are formulated in the format of linear matrix inequalities using the Lyapunov stability theory. The effectiveness of the proposed Strategy is finally demonstrated through a SAHPS (stand-alone hybrid power systems) to illustrate the effectiveness of the overall proposed method. (paper)

  13. Photovoltaic OLED Driver for Low-Power Stand-Alone Light-to-Light Systems

    DEFF Research Database (Denmark)

    Ploug, Rasmus Overgaard; Knott, Arnold

    2016-01-01

    Photovoltaic (PV) stand-alone systems need to achieve multiple energy conversion modes. I.e. the energy conversion from PV to a local energy storage as well as energy conversion from the energy storage to the load. This paper documents the practical design considerations for the development of a ...... conversion from photovoltaic panel to the battery, and 97 % in the area 1.4 W to 2 W for power delivery to the OLED.......Photovoltaic (PV) stand-alone systems need to achieve multiple energy conversion modes. I.e. the energy conversion from PV to a local energy storage as well as energy conversion from the energy storage to the load. This paper documents the practical design considerations for the development...... of a three-port-converter for this purpose optimized for the specifications for driving an Organic Light Emitting Diode (OLED) panel intended for lighting purposes. By using a three-port-converter, featuring shared components for each conversion mode, the converter reaches 97 % efficiency at 1.8 W during...

  14. Modified Chaos Particle Swarm Optimization-Based Optimized Operation Model for Stand-Alone CCHP Microgrid

    Directory of Open Access Journals (Sweden)

    Fei Wang

    2017-07-01

    Full Text Available The optimized dispatch of different distributed generations (DGs in stand-alone microgrid (MG is of great significance to the operation’s reliability and economy, especially for energy crisis and environmental pollution. Based on controllable load (CL and combined cooling-heating-power (CCHP model of micro-gas turbine (MT, a multi-objective optimization model with relevant constraints to optimize the generation cost, load cut compensation and environmental benefit is proposed in this paper. The MG studied in this paper consists of photovoltaic (PV, wind turbine (WT, fuel cell (FC, diesel engine (DE, MT and energy storage (ES. Four typical scenarios were designed according to different day types (work day or weekend and weather conditions (sunny or rainy in view of the uncertainty of renewable energy in variable situations and load fluctuation. A modified dispatch strategy for CCHP is presented to further improve the operation economy without reducing the consumers’ comfort feeling. Chaotic optimization and elite retention strategy are introduced into basic particle swarm optimization (PSO to propose modified chaos particle swarm optimization (MCPSO whose search capability and convergence speed are improved greatly. Simulation results validate the correctness of the proposed model and the effectiveness of MCPSO algorithm in the optimized operation application of stand-alone MG.

  15. Passive cooling of standalone flat PV module with cotton wick structures

    International Nuclear Information System (INIS)

    Chandrasekar, M.; Suresh, S.; Senthilkumar, T.; Ganesh karthikeyan, M.

    2013-01-01

    Highlights: • A simple passive cooling system is developed for standalone flat PV modules. • 30% Reduction in module temperature is observed with developed cooling system. • 15.61% Increase in output power of PV module is found with developed cooling system. • Module efficiency is increased by 1.4% with cooling arrangement. • Lower thermal degradation due to narrow range of temperature characteristics. - Abstract: In common, PV module converts only 4–17% of the incoming solar radiation into electricity. Thus more than 50% of the incident solar energy is converted as heat and the temperature of PV module is increased. The increase in module temperature in turn decreases the electrical yield and efficiency of the module with a permanent structural damage of the module due to prolonged period of thermal stress (also known as thermal degradation of the module). An effective way of improving efficiency and reducing the rate of thermal degradation of a PV module is to reduce the operating temperature of PV module. This can be achieved by cooling the PV module during operation. Hence in the present work, a simple passive cooling system with cotton wick structures is developed for standalone flat PV modules. The thermal and electrical performance of flat PV module with cooling system consisting of cotton wick structures in combination with water, Al 2 O 3 /water nanofluid and CuO/water nanofluid are investigated experimentally. The experimental results are also compared with the thermal and electrical performance of flat PV module without cooling system

  16. Stand-alone anterior lumbar interbody fusion for treatment of degenerative spondylolisthesis.

    Science.gov (United States)

    Rao, Prashanth J; Ghent, Finn; Phan, Kevin; Lee, Keegan; Reddy, Rajesh; Mobbs, Ralph J

    2015-10-01

    We sought to evaluate the clinical and radiologic efficacy of stand-alone anterior lumbar interbody fusion (ALIF) for low grade degenerative spondylolisthesis, the favoured surgical management approach at our institution. The optimal approach for surgical management of spondylolisthesis remains contentious. We performed a prospective analysis of all consecutive patients with low grade lumbar spondylolisthesis who underwent ALIF between 2009 and 2013 by a single surgeon (n=27). The mean age was 64.9 years with a male to female ratio of 14:13. There were 32 levels operated and the average preoperative spondylolisthesis was 14.8%, which reduced to 6.4% postoperatively and 9.4% at the latest follow-up (p=0001). Postoperative disc height was increased to 175% of preoperative values and was statistically significant (pspondylolisthesis reduction (p=0.04) and the only clinical factor affecting reduction was body mass index (p=0.04). The present study provides encouraging short term results for stand-alone ALIF as a procedure for low grade lumbar degenerative spondylolisthesis. Future studies should include adequately powered, prospective, multicentre registry studies with long term follow-up to allow a better assessment of the relative benefits and risks. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Modeling, Design and Simulation of Stand-Alone Photovoltaic Power Systems with Battery Storage

    Directory of Open Access Journals (Sweden)

    Abd Essalam BADOUD

    2013-06-01

    Full Text Available Stand alone renewable energy based on photovoltaic systems accompanied with battery storage system are beginning to play an important role over the world to supply power to remote areas. The objective of the study reported in this paper is to elaborate and design a bond graphs model for sizing stand-alone domestic solar photovoltaic electricity systems and simulating the performance of the systems in a tropical climate. The systems modelled consist of an array of PV modules, a lead-acid battery, and a number of direct current appliances. This paper proposes the combination of lead acid battery system with a typical stand alone photovoltaic energy system under variable loads. The main activities of this work purpose to establish library graphical models for each individual component of standalone photovoltaic system. Control strategy has been considered to achieve permanent power supply to the load via photovoltaic/battery based on the power available from the sun. The complete model was simulated under two testing including sunny and cloudy conditions. Simulation of the system using Symbols software was performed and the results of simulation show the superior stable control system and high efficiency. These results have been contrasted with real measured data from a measurement campaign plant carried on electrical engineering laboratory of Grenoble using various interconnection schemes are presented.

  18. International market assessment of stand-alone photovoltaic power systems for cottage industry applications

    Science.gov (United States)

    Philippi, T. M.

    1981-11-01

    The final result of an international assessment of the market for stand-alone photovoltaic systems in cottage industry applications is reported. Nonindustrialized countries without centrally planned economies were considered. Cottage industries were defined as small rural manufacturers, employing less than 50 people, producing consumer and simple products. The data to support this analysis were obtained from secondary and expert sources in the U.S. and in-country field investigations of the Philippines and Mexico. The near-term market for photovoltaics for rural cottage industry applications appears to be limited to demonstration projects and pilot programs, based on an in-depth study of the nature of cottage industry, its role in the rural economy, the electric energy requirements of cottage industry, and a financial analysis of stand-alone photovoltaic systems as compared to their most viable competitor, diesel driven generators. Photovoltaics are shown to be a better long-term option only for very low power requirements. Some of these uses would include clay mixers, grinders, centrifuges, lathes, power saws and lighting of a workshop.

  19. Design of a Stand-Alone Photovoltaic Model for Home Lightings and Clean Environment

    International Nuclear Information System (INIS)

    Ani, Vincent Anayochukwu

    2016-01-01

    This paper gives a well-documented health risk of fuel-based lighting (kerosene lamps and fuel-powered generators) and proposed a design of a stand-alone solar PV system for sustainable home lightings in rural Nigerian area. The design was done in three different patterns of electricity consumptions with energy efficient lightings (EELs) using two different battery types (Rolls Surrette 6CS25PS and Hoppecke 10 OpzS 1000) on; (i) judicious power consumption, (ii) normal power consumption, and (iii) excess power consumption; and compared them with the incandescent light bulb consumption. The stand-alone photovoltaic energy systems were designed to match the rural Nigerian sunlight and weather conditions to meet the required lightings of the household. The objective function and constraints for the design models were formulated and optimization procedures were used to demonstrate the best solution (reliability at the lowest lifecycle cost). Initial capital costs as well as annualized costs over 5, 10, 15, 20, and 25 years were quantified and documented. The design identified the most cost-effective and reliable solar and battery array among the patterns of electricity consumption with EEL options (judicious power consumption, normal power consumption, and excess power consumption).

  20. Design of a Stand-Alone Photovoltaic (PV Models for Home Lightings and Clean Environment

    Directory of Open Access Journals (Sweden)

    Vincent Anayochukwu Ani

    2016-01-01

    Full Text Available This paper gives a well-documented health risks of fuel-based lighting (kerosene lamps and fuel-powered generators and proposed a design of a stand-alone solar PV system for sustainable home lightings in rural Nigerian area. The design was done in three different patterns of electricity consumptions with energy efficient lightings (EELs using two different battery types (Rolls Surrette 6CS25PS and hoppecke 10 OpzS 1000 on; i judicious power consumption, ii normal power consumption, iii excess power consumption; and compared them with the incandescent light bulb consumption. The stand-alone photovoltaic energy systems were designed to match the rural Nigerian sunlight and weather conditions to meet the required lightings of the household. The objective function and constraints for the design models were formulated and optimization procedure were used to demonstrate the best solution (reliability at the lowest lifecycle cost. Initial capital costs as well as annualized costs over 5, 10, 15, 20, and 25 years were quantified and documented. The design identified the most cost-effective and reliable solar and battery array among the patterns of electricity consumption with energy efficient lighting options (judicious power consumption, normal power consumption, and excess power consumption.

  1. Design of Stand-Alone Hybrid Power Generation System at Brumbun Beach Tulungagung East Java

    Science.gov (United States)

    Rahmat, A. N.; Hidayat, M. N.; Ronilaya, F.; Setiawan, A.

    2018-04-01

    Indonesian government insists to optimize the use of renewable energy resources in electricity generation. One of the efforts is launching Independent Energy Village plan. This program aims to fulfill the need of electricity for isolated or remote villages in Indonesia. In order to support the penetration of renewable energy resources in electricity generation, a hybrid power generation system is developed. The simulation in this research is based on the availability of renewable energy resources in Brumbun beach, Tulungagung, East Java. Initially, the electricity was supplied through stand-alone electricity generations which are installed at each house. Hence, the use of electricity between 5 p.m. – 9 p.m. requires high operational costs. Based on the problem above, this research is conducted to design a stand-alone hybrid electricity generation system, which may consist of diesel, wind, and photovoltaic. The design is done by using HOMER software to optimize the use of electricity from renewable resources and to reduce the operation of diesel generation. The combination of renewable energy resources in electricity generation resulted in NPC of 44.680, COE of 0,268, and CO2 emissions of 0,038 % much lower than the use of diesel generator only.

  2. Dynamic modeling of an asynchronous squirrel-cage machine; Modelisation dynamique d'une machine asynchrone a cage

    Energy Technology Data Exchange (ETDEWEB)

    Guerette, D.

    2009-07-01

    This document presented a detailed mathematical explanation and validation of the steps leading to the development of an asynchronous squirrel-cage machine. The MatLab/Simulink software was used to model a wind turbine at variable high speeds. The asynchronous squirrel-cage machine is an electromechanical system coupled to a magnetic circuit. The resulting electromagnetic circuit can be represented as a set of resistances, leakage inductances and mutual inductances. Different models were used for a comparison study, including the Munteanu, Boldea, Wind Turbine Blockset, and SimPowerSystem. MatLab/Simulink modeling results were in good agreement with the results from other comparable models. Simulation results were in good agreement with analytical calculations. 6 refs, 2 tabs, 9 figs.

  3. Validation of a self-administered modified CAGE test (CAGE-C) in a somatic hospital ward: comparison with biochemical markers

    DEFF Research Database (Denmark)

    Zierau, F; Hardt, F; Henriksen, Jens Henrik Sahl

    2005-01-01

    Objective. The time frame for the original CAGE questionnaire is lifetime and it does not quantify drinking frequency and may be less suitable in a population with very few teetotalers. The purpose of this study was to validate a variant of the CAGE questionnaire and compare it with the outcome...

  4. Cage drying and the application of a dry treatment (absorbent cornstarch powder) as a means to diminish Campylobacter on transport cages.

    Science.gov (United States)

    Broiler transport cages soiled with Campylobacter-positive feces have been shown to facilitate cross contamination of broilers. Campylobacter organisms are sensitive to dry stress. Allowing feces left on transport cage flooring to dry during extended periods of nonuse would be an effective method ...

  5. New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups

    Czech Academy of Sciences Publication Activity Database

    Palma-Cerda, F.; Auger, C.; Crawford, D.J.; Hodgson, A.C.C.; Reynolds, S.J.; Cowell, J.K.; Swift, K.A.D.; Cais, Ondřej; Vyklický ml., Ladislav; Corrie, J.E.T.; Ogden, D.

    2012-01-01

    Roč. 63, č. 4 (2012), s. 624-634 ISSN 0028-3908 R&D Projects: GA ČR(CZ) GA309/07/0271 Grant - others:EC(XE) LSHM-CT-2007-037765 Institutional research plan: CEZ:AV0Z50110509 Keywords : photolysis * glutamate receptors * caged neurotransmitters Subject RIV: ED - Physiology Impact factor: 4.114, year: 2012

  6. Development of 4-methoxy-7-nitroindolinyl (MNI)-caged auxins which are extremely stable in planta.

    Science.gov (United States)

    Hayashi, Ken-Ichiro; Kusaka, Naoyuki; Yamasaki, Soma; Zhao, Yunde; Nozaki, Hiroshi

    2015-10-15

    Phytohormone auxin is a master regulator in plant growth and development. Regulation of cellular auxin level plays a central role in plant development. Auxin polar transport system modulates an auxin gradient that determines plant developmental process in response to environmental conditions and developmental programs. Photolabile caged auxins allow optical control of artificial auxin gradients at cellular resolution. Especially, two-photon uncaging system achieves high spatiotemporal control of photolysis reaction at two-photon cross-section. However, the development of caged versions of auxin has been limited by the instability of the caged auxins to higher plant metabolic activities. Here, we describe the synthesis and application of highly stable caged auxins, 4-methoxy-7-nitroindolinyl (MNI)-caged auxins. Natural auxin, indole 3-acetic acid, and two synthetic auxins, 1-NAA and 2,4-D were caged by MNI caging group. MNI-caged auxins showed a high stability in planta and a rapid release the original auxin when photolyzed. We demonstrated that optical control of auxin-responsive gene expression and auxin-related physiological responses by using MNI-caged auxins. We anticipate that MNI-caged auxins will be an effective tool for high-resolution control of endogenous auxin level. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Graft Subsidence and Revision Rates Following Anterior Cervical Corpectomy: A Clinical Study Comparing Different Interbody Cages.

    Science.gov (United States)

    Weber, Michael H; Fortin, Maryse; Shen, Jian; Tay, Bobby; Hu, Serena S; Berven, Sigurd; Burch, Shane; Chou, Dean; Ames, Christopher; Deviren, Vedat

    2017-11-01

    Retrospective cohort study. To assess the subsidence and revision rates associated with different interbody cages following anterior cervical corpectomy and reconstruction. Different interbody cages are currently used for surgical reconstruction of the anterior and middle columns of the spine following anterior cervical corpectomy. However, subsidence and delayed union/nonunion associated with allograft and cage reconstruction are common complications, which may require revision with instrumentation. We reviewed the cases of 75 patients who underwent cervical corpectomy and compared the radiographic graft subsidence and revision rates for fibula allograft, titanium mesh cage, titanium expandable cage, and carbon fiber cages. Subsidence was calculated by comparing the immediate postoperative lateral x-ray films to those obtained during follow-up visits. The average graft subsidence was 3 mm and revision rate was 25% for fibula allograft versus 2.9 mm and 11.1%, 2.9 mm and 18.8% for titanium mesh cages and titanium expandable cages, respectively. The average graft subsidence for carbon fiber cages was 0.7 mm with no revision surgery in this subset. Our findings suggest that subsidence and revision rates following anterior corpectomy and interbody fusion could be minimized with the use of a carbon fiber cage.

  8. Effects of Furnished Cage Type on Behavior and Welfare of Laying Hens

    Science.gov (United States)

    Li, Xiang; Chen, Donghua; Li, Jianhong; Bao, Jun

    2016-01-01

    This study was conducted to compare the effects of layout of furniture (a perch, nest, and sandbox) in cages on behavior and welfare of hens. Two hundred and sixteen Hyline Brown laying hens were divided into five groups (treatments) with four replicates per group: small furnished cages (SFC), medium furnished cages type I (MFC-I), medium furnished cages type II (MFC-II), and medium furnished cages type III (MFC-III) and conventional cages (CC). The experiment started at 18 week of age and finished at 52 week of age. Hens’ behaviors were filmed during the following periods: 8:00 to 10:00; 13:00 to 14:00; 16:00 to 17:00 on three separate days and two hens from each cage were measured for welfare parameters at 50 wk of age. The results showed that feeding and laying of all hens showed no effect by cage type (p>0.05), and the hens in the furnished cages had significantly lower standing and higher walking than CC hens (phens between the furnished cages (p>0.05). The hens in MFC-I, −II, and −III showed a significant higher socializing behavior than SFC and CC (phens in SFC and the highest perching found for the hens in MFC-III. Overall, the hens in CC showed poorer welfare conditions than the furnished cages, in which the feather condition score, gait score and tonic immobility duration of the hens in CC was significantly higher than SFC, MFC-I, MFC-II, and MFC-III (phens. Overall, MFC-III cage design was better than SFC, MFC-I, and MFC-II cage designs. PMID:26954171

  9. Effects of Furnished Cage Type on Behavior and Welfare of Laying Hens

    Directory of Open Access Journals (Sweden)

    Xiang Li

    2016-06-01

    Full Text Available This study was conducted to compare the effects of layout of furniture (a perch, nest, and sandbox in cages on behavior and welfare of hens. Two hundred and sixteen Hyline Brown laying hens were divided into five groups (treatments with four replicates per group: small furnished cages (SFC, medium furnished cages type I (MFC-I, medium furnished cages type II (MFC-II, and medium furnished cages type III (MFC-III and conventional cages (CC. The experiment started at 18 week of age and finished at 52 week of age. Hens’ behaviors were filmed during the following periods: 8:00 to 10:00; 13:00 to 14:00; 16:00 to 17:00 on three separate days and two hens from each cage were measured for welfare parameters at 50 wk of age. The results showed that feeding and laying of all hens showed no effect by cage type (p>0.05, and the hens in the furnished cages had significantly lower standing and higher walking than CC hens (p0.05. The hens in MFC-I, −II, and −III showed a significant higher socializing behavior than SFC and CC (p<0.05. The lowest perching was for the hens in SFC and the highest perching found for the hens in MFC-III. Overall, the hens in CC showed poorer welfare conditions than the furnished cages, in which the feather condition score, gait score and tonic immobility duration of the hens in CC was significantly higher than SFC, MFC-I, MFC-II, and MFC-III (p<0.05. In conclusion, the furnished cage design affected both behavior and welfare states of hens. Overall, MFC-III cage design was better than SFC, MFC-I, and MFC-II cage designs.

  10. Incidence and clinical relevance of cage subsidence in anterior cervical discectomy and fusion: a systematic review.

    Science.gov (United States)

    Noordhoek, Iris; Koning, Marvyn T; Jacobs, Wilco C H; Vleggeert-Lankamp, Carmen L A

    2018-04-01

    The placement of intervertebral cages in anterior cervical discectomy (ACDF) supposedly maintains foraminal height. The most commonly reported cage-related complication is subsidence, although it is unknown whether a correlation between subsidence and clinical outcome exists. To assess the incidence and relevance of subsidence. Literature searches were performed in PubMed, MEDLINE, Embase, Web of Science, COCHRANE, and CENTRAL. The inclusion criteria were as follows: ≥ 20 patients, ADCF with cage, subsidence assessed, and primary data. Risk of bias was assessed using adjusted Cochrane checklists. Seventy-one studies, comprising 4784 patients, were included. Subsidence was generally defined as ≥ 3-mm loss of height comparing postoperative intervertebral heights with heights at last follow-up. Mean incidence of subsidence was 21% (range 0-83%). Of all patients, 46% of patients received polyether-ether-ketone (PEEK) cages, 31% received titanium cages, 18% received cage-screw-combinations, and 5% received polymethyl-methacrylate (PMMA) cages. Patients treated with cage-screw-combinations had significantly less subsidence than patients treated with PEEK, titanium, or PMMA cages (15.1% vs. 23.5% vs. 24.9% vs. 30.2%; p subsidence; the majority did not find a significant correlation. Only four studies correlated subsidence to cage size and/or height; no correlation was established. Subsidence in ACDF with cages occurs in 21% of patients. The risk for subsidence seems lower using PEEK or titanium cages or adding screws. Whether subsidence affects clinical outcome is not satisfactorily evaluated in the available literature. Future studies on this correlation are warranted in order to establish the additional value of the interposition of a cage in ACDF.

  11. Elimination of Subsidence with 26-mm-Wide Cages in Extreme Lateral Interbody Fusion.

    Science.gov (United States)

    Lang, Gernot; Navarro-Ramirez, Rodrigo; Gandevia, Lena; Hussain, Ibrahim; Nakhla, Jonathan; Zubkov, Micaella; Härtl, Roger

    2017-08-01

    Extreme lateral interbody fusion (ELIF) has gained popularity as a minimally invasive technique for indirect decompression. However, graft subsidence potentially threatens long-term success of ELIF. This study evaluated whether 26-mm-wide cages can eliminate subsidence and subsequent loss of decompression in ELIF. Patients undergoing ELIF surgery using a 26-mm-wide cage were analyzed retrospectively. Patient demographics and perioperative data for radiographic and clinical outcomes were recorded. Radiographic parameters included regional sagittal lumbar lordosis and foraminal and disc height. Clinical parameters were evaluated using the Oswestry Disability Index and visual analog scale. Subsidence of 26-mm-wide cages was compared with previous outcomes of patients undergoing ELIF using 18-mm-wide and 22-mm-wide cages. There were 21 patients and 28 spinal segments analyzed. Radiographic outcome measures such as disc and foraminal height revealed significant improvement at follow-up compared with before surgery (P = 0.001). Postoperative to last follow-up cage subsidence translated into 0.34 mm ± 0.26 and -0.55 mm ± 0.64 in disc and foraminal height loss, respectively. Patients with 26-mm-wide cages experienced less subsidence by means of disc (26 mm vs. 18 mm and 22 mm, P ≤ 0.05) and foraminal height (26 mm vs. 18 mm, P = 0.005; 26 mm vs. 22 mm, P = 0.208) loss compared with patients receiving 18-mm-wide and 22-mm-wide cages. The 26-mm-wide cages almost eliminated cage subsidence in ELIF. Compared with 18-mm-wide and 22-mm-wide cages, 26-mm-wide cages significantly reduced cage subsidence in ELIF at midterm follow-up. A 26-mm-wide cage should be used in ELIF to achieve sustained indirect decompression. Copyright © 2017. Published by Elsevier Inc.

  12. The Impact of a Standalone, Patient-centered Communication Course Series on Student Achievement, Preparedness, and Attitudes

    Science.gov (United States)

    McNair, Chelsea D.; Linnebur, Sunny A.; Valdez, Connie; Trujillo, Toby C.

    2016-01-01

    Objective. To evaluate the impact of a standalone, patient-centered communication (PCC) course series on student achievement of and perceived preparedness for PCC skills and to assess student attitudes regarding learning methods used. Design. During curriculum renewal, a standalone PCC course series that integrated horizontally and vertically within the curriculum was developed. Student achievement of outcomes was evaluated by aggregate performance on simulated evaluations. Students who completed the PCC series were surveyed to assess preparedness and attitudes. Students in the prior curriculum were also surveyed. Assessment. The majority of students who completed the PCC series met or exceeded expectations for the simulated evaluations. Preparedness responses were more positive from students who completed the PCC series than from those who completed the prior curriculum. Student attitudes about the learning methods use in the courses also were more positive. Conclusion. The standalone PCC course series effectively achieved PCC outcomes and improved student preparedness for communication-based activities. PMID:28179723

  13. Charactrization of a Li-ion battery based stand-alone a-Si photovoltaic system

    International Nuclear Information System (INIS)

    Hamid Vishkasougheh, Mehdi; Tunaboylu, Bahadir

    2014-01-01

    Highlights: • An Li-ion battery based stand-alone a-Si PV was designed. The system composed of three a-Si panels with an efficiency of 7% and 40 cells of LFP batteries. • Effects of solar radiation and environmental temperature for three cities, Istanbul, Ankara, and Adana, have been investigated on a-Si panels. • Using transition formulas BSPV outputs are predictable for any location out of standard test condition. - Abstract: The number of photovoltaic (PV) system installations is increasing rapidly. As more people learn about this versatile and often cost-effective power option, this trend will accelerate. This document presents a recommended design for a battery based stand-alone photovoltaic system (BSPV). BSPV system has the ability to be applied in different areas, including warning signals, lighting, refrigeration, communication, residential water pumping, remote sensing, and cathodic protection. The presented calculation method gives a proper idea for a system sizing technique. Based on application load, different scenarios are possible for designing a BSPV system. In this study, a battery based stand-alone system was designed. The electricity generation part is three a-Si panels, which are connected in parallel, and for the storage part LFP (lithium iron phosphate) battery was used. The high power LFP battery packs are 40 cells each 8S5P (configured 8 series 5 parallel). Each individual pack weighs 0.5 kg and is 25.6 V. In order to evaluate the efficiency of a-Si panels with respect to the temperature and the solar irradiation, cities of Istanbul, Ankara and Adana in Turkey were selected. Temperature and solar irradiation were gathered from reliable sources and by using translation equations, current and voltage output of panels were calculated. As a result of these calculations, current and energy outputs were computed by considering an average efficient solar irradiation time value per day in Turkey. The calculated power values were inserted to a

  14. Flexible Control of Small Wind Turbines With Grid Failure Detection Operating in Stand-Alone and Grid-Connected Mode

    DEFF Research Database (Denmark)

    Teodorescu, Remus; Blaabjerg, Frede

    2004-01-01

    This paper presents the development and test of a flexible control strategy for an 11-kw wind turbine with a back-to-back power converter capable of working in both stand-alone and grid-connected mode. The stand-alone control is featured with a complex output voltage controller capable of handling...... nonlinear load and excess or deficit of generated power. Grid-connection mode with current control is also enabled for the case of isolated local grid involving other dispersed power generators such as other wind turbines or diesel generators. A novel automatic mode switch method based on a phase...

  15. Stand-alone differential capacitance force sensors with sub-nano-newton sensitivity

    Science.gov (United States)

    Ye, Jilong; Sun, Taotao; Huang, Dong; Li, Zhihong; Lin, Li

    2017-09-01

    This paper presents structure design, microfabrication processes, calibration techniques and experimental results of differential capacitance force sensors with features of sub-nano-newton sensitivity, up to 10 000 Hz sampling rate, and applicability as stand-alone devices. The representative sensor demonstrates a force resolution of 0.11 nN at a 19 Hz sampling rate or 1.47 nN at 10 000 Hz. A novel asymmetric differential capacitance structure proposed results in remarkable increase in the ratio of measurement range to resolution in comparison with traditional symmetric structure. In addition, the stiction between silicon and glass caused by the capillary force during dicing is eliminated by the use of hydrophobization treatment. Such a treatment is essential to successfully fabricate structures with a large ratio of overlapped area to gap in silicon/glass anodic bonding processes.

  16. Cost estimation of a standalone photovoltaic power system in remote areas of Sarawak, Malaysia

    International Nuclear Information System (INIS)

    Jakhrani, A.Q.; Othman, A.K.; Rigit, A.R.H.; Samo, S.R.

    2012-01-01

    This paper aims to estimate the anticipated costs incurred from a standalone solar photovoltaic power system for the supply of electricity to the rural community in Sarawak, Malaysia. The life cycle cost analysis with net present value technique was employed for the evaluation of cost system. It was found that purchasing of solar photovoltaic components and the system installation cost will contribute 63% of the total investment and future anticipated costs will add to the remaining. Recurring cost will make 25% and components replacements 75% of future anticipated costs. It was discovered that the power generated from the solar photovoltaic system would be 38 times more expensive than electricity produced from the conventional sources. However, its installation in remote areas could be favourable where the grid-connected power supply is not accessible. (author)

  17. Study of Stand-Alone Microgrid under Condition of Faults on Distribution Line

    Science.gov (United States)

    Malla, S. G.; Bhende, C. N.

    2014-10-01

    The behavior of stand-alone microgrid is analyzed under the condition of faults on distribution feeders. During fault since battery is not able to maintain dc-link voltage within limit, the resistive dump load control is presented to do so. An inverter control is proposed to maintain balanced voltages at PCC under the unbalanced load condition and to reduce voltage unbalance factor (VUF) at load points. The proposed inverter control also has facility to protect itself from high fault current. Existing maximum power point tracker (MPPT) algorithm is modified to limit the speed of generator during fault. Extensive simulation results using MATLAB/SIMULINK established that the performance of the controllers is quite satisfactory under different fault conditions as well as unbalanced load conditions.

  18. Standalone Mobile Application for Shipping Services Based on Geographic Information System and A-Star Algorithm

    Science.gov (United States)

    Gunawan, D.; Marzuki, I.; Candra, A.

    2018-03-01

    Geographic Information Systems (GIS) plays an essential role in shipping service related application. By utilizing GIS, the courier can find the route to deliver goods for its customer. This research proposes a standalone mobile application to provide the shortest route to the destinations by utilizing geographic information systems with A-Star algorithm. This application is intended to be used although the area has no Internet network available. The developed application can handle several drop off points then calculates the shortest route that passes through all the drop off points. According to the conducted testing, the number of drop off points that can be calculated is influenced by the specification of the smartphone. More destinations require more smartphone resources and time to process.

  19. Solar pv fed stand-alone excitation system of a synchronous machine for reactive power generation

    Science.gov (United States)

    Sudhakar, N.; Jain, Siddhartha; Jyotheeswara Reddy, K.

    2017-11-01

    This paper presents a model of a stand-alone solar energy conversion system based on synchronous machine working as a synchronous condenser in overexcited state. The proposed model consists of a Synchronous Condenser, a DC/DC boost converter whose output is fed to the field of the SC. The boost converter is supplied by the modelled solar panel and a day time variable irradiance is fed to the panel during the simulation time. The model also has one alternate source of rechargeable batteries for the time when irradiance falls below a threshold value. Also the excess power produced when there is ample irradiance is divided in two parts and one is fed to the boost converter while other is utilized to recharge the batteries. A simulation is done in MATLAB-SIMULINK and the obtained results show the utility of such modelling for supplying reactive power is feasible.

  20. Transforming stand-alone expert system into a community of cooperating agents

    CERN Document Server

    Jennings, N R; Aarnts, R P; Fuchs, J; Skarek, Paul

    1993-01-01

    Distributed Artificial Intelligence (DAI) systems in which multiple problem solving agents cooperate to achieve a common objective is a rapidly emerging and promising technology. However, as yet, there have been relatively few reported cases of such systems being employed to tackle real-world problems in realistic domains. One of the reasons for this is that DAI researchers have given virtually no consideration to the process of incorporating pre-existing systems into a community of cooperating agents. Yet reuse is a primary consideration for any organisation with a large software base. To redress the balance, this paper reports on an experiment undertaken at the CERN laboratories, in which two pre-existing and standalone expert systems for diagnosing faults in a particle accelerator were transformed into a community of cooperating agents. The experiences and insights gained during this process provide a valuable first step towards satisfying the needs of potential users of DAI technology - identifying the ty...

  1. Electrical integration of renewable energy into stand-alone power supplies incorporating hydrogen storage

    Energy Technology Data Exchange (ETDEWEB)

    Little, Matthew; Thomson, Murray

    2007-07-15

    A stand-alone renewable-energy system employing a hydrogen-based energy store is now being commissioned within the HaRI project at West Beacon Farm, Leicestershire, UK. The interconnection of the various generators, loads and storage system is made through a central DC busbar: an arrangement that is believed to be unique within systems of this type and scale. The rotating generators, such as the wind turbines, are connected through standard industrial drives operating in regenerative mode, while the DC devices - electrolyser, fuel cell and solar photovoltaic array - employ custom DC-DC converters. This paper reviews the design philosophy of the electrical system and the various converters required. Modelling and simulation of the system is discussed along with practical lessons learnt from its implementation and some initial results are presented. (author)

  2. STANDALONE PHOTOVOLTAIC SYSTEMS SIZING OPTIMIZATION USING DESIGN SPACE APPROACH: CASE STUDY FOR RESIDENTIAL LIGHTING LOAD

    Directory of Open Access Journals (Sweden)

    D. F. AL RIZA

    2015-07-01

    Full Text Available This paper presents a sizing optimization methodology of panel and battery capacity in a standalone photovoltaic system with lighting load. Performance of the system is identified by performing Loss of Power Supply Probability (LPSP calculation. Input data used for the calculation is the daily weather data and system components parameters. Capital Cost and Life Cycle Cost (LCC is calculated as optimization parameters. Design space for optimum system configuration is identified based on a given LPSP value, Capital Cost and Life Cycle Cost. Excess energy value is used as an over-design indicator in the design space. An economic analysis, including cost of the energy and payback period, for selected configurations are also studied.

  3. Standalone Terrestrial Laser Scanning for Efficiently Capturing Aec Buildings for As-Built Bim

    Science.gov (United States)

    Bassier, M.; Vergauwen, M.; Van Genechten, B.

    2016-06-01

    With the increasing popularity of as-built building models for the architectural, engineering and construction (AEC) industry, the demand for highly accurate and dense point cloud data is rising. The current data acquisition methods are labour intensive and time consuming. In order to compete with indoor mobile mapping systems (IMMS), surveyors are now opting to use terrestrial laser scanning as a standalone solution. However, there is uncertainty about the accuracy of this approach. The emphasis of this paper is to determine the scope for which terrestrial laser scanners can be used without additional control. Multiple real life test cases are evaluated in order to identify the boundaries of this technique. Furthermore, this research presents a mathematical prediction model that provides an indication of the data accuracy given the project dimensions. This will enable surveyors to make informed discussions about the employability of terrestrial laser scanning without additional control in mid to large-scale projects.

  4. System Simulation by Recursive Feedback: Coupling a Set of Stand-Alone Subsystem Simulations

    Science.gov (United States)

    Nixon, D. D.

    2001-01-01

    Conventional construction of digital dynamic system simulations often involves collecting differential equations that model each subsystem, arran g them to a standard form, and obtaining their numerical gin solution as a single coupled, total-system simultaneous set. Simulation by numerical coupling of independent stand-alone subsimulations is a fundamentally different approach that is attractive because, among other things, the architecture naturally facilitates high fidelity, broad scope, and discipline independence. Recursive feedback is defined and discussed as a candidate approach to multidiscipline dynamic system simulation by numerical coupling of self-contained, single-discipline subsystem simulations. A satellite motion example containing three subsystems (orbit dynamics, attitude dynamics, and aerodynamics) has been defined and constructed using this approach. Conventional solution methods are used in the subsystem simulations. Distributed and centralized implementations of coupling have been considered. Numerical results are evaluated by direct comparison with a standard total-system, simultaneous-solution approach.

  5. Plastic cages to protect Douglas-fir seedlings from animal damage in western Oregon.

    Science.gov (United States)

    Glen C. Crouch

    1980-01-01

    Effects of plastic mesh cages designed to protect Douglas-fir seedlings from animals were evaluated in western Oregon. In two tests over 5-year periods, caging increased survival by 0 and 13 percent and increased height growth by 0.8 and 1.2 feet compared with uncaged trees. Benefits from caging might have been greater if damage had been more prevalent during the tests...

  6. Standard methods for maintaining adult Apis mellifera in cages under in vitro laboratory conditions

    OpenAIRE

    Williams, Geoffrey R.; Alaux, Cedric; Costa, Cecilia; Csaki, Tamas; Doublet, Vincent; Eisenhardt, Dorothea; Fries, Ingemar; Kuhn, Rolf; McMahon, Dino P.; Medrzycki, Piotr; Murray, Tomas E.; Natsopoulou, Myrsini E.; Neumann, Peter; Oliver, Randy; Paxton, Robert J.

    2013-01-01

    Adult honey bees are maintained in vitro in laboratory cages for a variety of purposes. For example, researchers may wish to perform experiments on honey bees caged individually or in groups to study aspects of parasitology, toxicology, or physiology under highly controlled conditions, or they may cage whole frames to obtain newly emerged workers of known age cohorts. Regardless of purpose, researchers must manage a number of variables, ranging from selection of study subjects (e.g. honey bee...

  7. Standard methods for maintaining adult Apis mellifera in cages under in vitro laboratory conditions

    OpenAIRE

    Williams, G.R.; Alaux, C.; Costa, C.; Csaki, C.; Steen, van der, J.J.M.

    2013-01-01

    Adult honey bees are maintained in vitro in laboratory cages for a variety of purposes. For example, researchers may wish to perform experiments on honey bees caged individually or in groups to study aspects of parasitology, toxicology, or physiology under highly controlled conditions, or they may cage whole frames to obtain freshly emerged workers of known age cohorts. Regardless of purpose, researchers must manage a number of variables, ranging from selection of study subjects (e.g. honey b...

  8. Lumbar interbody fusion: a parametric investigation of a novel cage design with and without posterior instrumentation.

    Science.gov (United States)

    Galbusera, Fabio; Schmidt, Hendrik; Wilke, Hans-Joachim

    2012-03-01

    A finite element model of the L4-L5 human segment was employed to carry out a parametric biomechanical investigation of lumbar interbody fusion with a novel "sandwich" cage having an inner stiff core and two softer layers in the areas close to the endplates, with and without posterior fixation. Considered cage designs included: (a) cage in a homogeneous material with variable elastic modulus (19-2,000 MPa), (b) "sandwich" cage having an inner core (E=2,000 MPa) and softer layers (E=19 MPa) with variable thickness (1-2.5 mm). The latter cage was also considered in combination with posterior rods made with a material having variable elastic modulus (19-210,000 MPa). All the models were loaded with 500 N compression and moments of 7.5 Nm in flexion, extension, lateral bending and axial rotation. The homogeneous cage stabilized the segment in flexion, lateral bending and axial rotation; in extension there was a destabilization up to 60% and remarkable cage movement (1 mm). The "sandwich" cage limited this phenomenon (cage movement<0.6 mm), effectively stabilized the segment in the other directions and lowered the maximal contact pressure on the endplates, reducing the risk of subsidence. Posterior fixation reduced spinal flexibility and cage movement. The soft layers of the "sandwich" cage had the potential to limit the risk of cage subsidence and to preserve a significant loading of the structure even in combination with flexible posterior instrumentation, which may have a beneficial effect in promoting bony fusion.

  9. Greenhouse Gas Emissions from Three Cage Layer Housing Systems

    Directory of Open Access Journals (Sweden)

    John Feddes

    2011-12-01

    Full Text Available Agriculture accounts for 10 to 12% of the World’s total greenhouse gas (GHG emissions. Manure management alone is responsible for 13% of GHG emissions from the agricultural sector. During the last decade, Québec’s egg production systems have shifted from deep-pit housing systems to manure belt housing systems. The objective of this study was to measure and compare carbon dioxide (CO2, methane (CH4 and nitrous oxide (N2O emissions from three different cage layer housing systems: a deep liquid manure pit and a manure belt with natural or forced air drying. Deep liquid manure pit housing systems consist of “A” frame layer cages located over a closed pit containing the hens’ droppings to which water is added to facilitate removal by pumping. Manure belt techniques imply that manure drops on a belt beneath each row of battery cages where it is either dried naturally or by forced air until it is removed. The experiment was replicated with 360 hens reared into twelve independent bench-scale rooms during eight weeks (19–27 weeks of age. The natural and forced air manure belt systems reduced CO2 (28.2 and 28.7 kg yr−1 hen−1, respectively, CH4 (25.3 and 27.7 g yr−1 hen−1, respectively and N2O (2.60 and 2.48 g yr−1 hen−1, respectively emissions by about 21, 16 and 9% in comparison with the deep-pit technique (36.0 kg CO2 yr−1 hen−1, 31.6 g CH4 yr−1 hen−1 and 2.78 g N2O yr−1 hen−1. The shift to manure belt systems needs to be encouraged since this housing system significantly decreases the production of GHG.

  10. Standalone BISON Fuel Performance Results for Watts Bar Unit 1, Cycles 1-3

    Energy Technology Data Exchange (ETDEWEB)

    Clarno, Kevin T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Pawlowski, Roger [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Stimpson, Shane [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Powers, Jeffrey [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-03-07

    The Consortium for Advanced Simulation of Light Water Reactors (CASL) is moving forward with more complex multiphysics simulations and increased focus on incorporating fuel performance analysis methods. The coupled neutronics/thermal-hydraulics capabilities within the Virtual Environment for Reactor Applications Core Simulator (VERA-CS) have become relatively stable, and major advances have been made in analysis efforts, including the simulation of twelve cycles of Watts Bar Nuclear Unit 1 (WBN1) operation. While this is a major achievement, the VERA-CS approaches for treating fuel pin heat transfer have well-known limitations that could be eliminated through better integration with the BISON fuel performance code. Several approaches are being implemented to consider fuel performance, including a more direct multiway coupling with Tiamat, as well as a more loosely coupled one-way approach with standalone BISON cases. Fuel performance typically undergoes an independent analysis using a standalone fuel performance code with manually specified input defined from an independent core simulator solution or set of assumptions. This report summarizes the improvements made since the initial milestone to execute BISON from VERA-CS output. Many of these improvements were prompted through tighter collaboration with the BISON development team at Idaho National Laboratory (INL). A brief description of WBN1 and some of the VERA-CS data used to simulate it are presented. Data from a small mesh sensitivity study are shown, which helps justify the mesh parameters used in this work. The multi-cycle results are presented, followed by the results for the first three cycles of WBN1 operation, particularly the parameters of interest to pellet-clad interaction (PCI) screening (fuel-clad gap closure, maximum centerline fuel temperature, maximum/minimum clad hoop stress, and cumulative damage index). Once the mechanics of this capability are functioning, future work will target cycles with

  11. Robust Frequency and Voltage Stability Control Strategy for Standalone AC/DC Hybrid Microgrid

    Directory of Open Access Journals (Sweden)

    Furqan Asghar

    2017-05-01

    Full Text Available The microgrid (MG concept is attracting considerable attention as a solution to energy deficiencies, especially in remote areas, but the intermittent nature of renewable sources and varying loads cause many control problems and thereby affect the quality of power within a microgrid operating in standalone mode. This might cause large frequency and voltage deviations in the system due to unpredictable output power fluctuations. Furthermore, without any main grid support, it is more complex to control and manage the system. In past, droop control and various other coordination control strategies have been presented to stabilize the microgrid frequency and voltages, but in order to utilize the available resources up to their maximum capacity in a positive way, new and robust control mechanisms are required. In this paper, a standalone microgrid is presented, which integrates renewable energy-based distributed generations and local loads. A fuzzy logic-based intelligent control technique is proposed to maintain the frequency and DC (direct current-link voltage stability for sudden changes in load or generation power. Also from a frequency control perspective, a battery energy storage system (BESS is suggested as a replacement for a synchronous generator to stabilize the nominal system frequency as a synchronous generator is unable to operate at its maximum efficiency while being controlled for stabilization purposes. Likewise, a super capacitor (SC and BESS is used to stabilize DC bus voltages even though maximum possible energy is being extracted from renewable generated sources using maximum power point tracking. This newly proposed control method proves to be effective by reducing transient time, minimizing the frequency deviations, maintaining voltages even though maximum power point tracking is working and preventing generators from exceeding their power ratings during disturbances. However, due to the BESS limited capacity, load switching

  12. Energy management system for stand-alone diesel-wind-biomass microgrid with energy storage system

    International Nuclear Information System (INIS)

    Wang, Chengshan; Liu, Yixin; Li, Xialin; Guo, Li; Qiao, Lei; Lu, Hai

    2016-01-01

    An energy management system for stand-alone microgrid composed of diesel generators, wind turbine generator, biomass generator and an ESS (energy storage system) is proposed in this paper. Different operation objectives are achieved by a hierarchical control structure with different time scales. Firstly, the optimal schedules of the diesel generators, wind turbine generator, biomass generator and ESS are determined fifteen minutes ahead according to the super short-term forecast of load and wind speed in the optimal scheduling layer. Comprehensive analysis which takes the uncertainty of load and wind speed into account is conducted in this layer to minimize the operation cost of the system and ensure a desirable range of the state of charge of the ESS. Secondly, the operation points of each unit are regulated dynamically to guarantee real-time power balance and safety range of diesel generation in the real-time control layer, based on which the response capability when suffering significant forecast deviation and other emergency issues, e.g. sudden load-up can be improved. Finally, the effectiveness of the proposed energy management strategy is verified on an RT_Lab based real-time simulation platform, and the economic performances with different types of ESS are analyzed as well. - Highlights: • A hierarchical control strategy is proposed for a stand-alone microgrid. • The uncertainties of load and wind speed have been considered. • Better economic performance and high reliability of the system can be achieved. • The influences of different energy storage systems have been analyzed.

  13. Optimal expansion planning of stand-alone systems with stochastic simulations

    Energy Technology Data Exchange (ETDEWEB)

    Hoese, Alejandro [Instituto de Energia Electrica (IEE), Universidad Nacional de San Juan, (Argentina)

    1997-12-31

    Stand-alone systems in the range of 1 kW - 10 MW are taking relevance in the new (global) liberal concept of energy market. State and private investors are becoming increasingly attention on the use of renewable for these systems, but it must be shown that these non-conventional solutions are competitive with the established conventional ones. The high investment costs and the technical and economic uncertainties coupled with the use of time-dependent energy sources are the mainly inhibiting factors for the decision agents to choose these systems instead of conventional ones. In the paper a new model for optimal expansion planning of hybrid stand-alone generating systems under consideration of uncertainties is presented. This model is at present in {sup d}evelopment state{sup .} Results already obtained in the first steps of this research are promising and some of them are here presented. [Espanol] Los sistemas autocontenidos en el rango de 1 Kw a 10 MW estan tomando importancia en el nuevo (global) concepto liberal del mercado de la energia. Inversionistas privados y del Estado estan poniendo mayor atencion en el uso de energias renovables para estos sistemas, pero debe mostrarse que estas soluciones no-convencionales son competitivas con las convencionales establecidas. Los altos costos de inversion y las incertidumbres tecnicas y economicas aunadamente con el uso de fuentes de energia dependientes del tiempo son los principales factores inhibidores de los factores de decision para escoger estos sistemas en lugar de los convencionales. En este articulo se presenta un nuevo modelo de planeacion de expansion optima de sistemas hibridos autocontenidos de generacion electrica bajo la consideracion de incertidumbres. Este modelo esta actualmente en {sup e}stado de desarrollo{sup .} Los resultados ya obtenidos en las primeras etapas de esta investigacion son prometedores y se presentan algunos de ellos.

  14. Diagnostic value of the stand-alone synthetic image in digital breast tomosynthesis examinations.

    Science.gov (United States)

    Garayoa, Julia; Chevalier, Margarita; Castillo, Maria; Mahillo-Fernández, Ignacio; Amallal El Ouahabi, Najim; Estrada, Carmen; Tejerina, Alejandro; Benitez, Olivia; Valverde, Julio

    2018-02-01

    To demonstrate the non-inferiority of synthetic image (SI) mammography versus full-field digital mammography (FFDM) in breast tomosynthesis (DBT) examinations. An observational, retrospective, single-centre, multireader blinded study was performed, using 2384 images to directly compare SI and FFDM based on Breast Imaging Reporting and Data System (BIRADS) categorisation and visibility of radiological findings. Readers had no access to digital breast tomosynthesis slices. Multiple reader, multiple case (MRMC) receiver operating characteristic (ROC) methodology was used to compare the diagnostic performance of SI and FFDM images. The kappa statistic was used to estimate the inter-reader and intra-reader reliability. The area under the ROC curves (AUC) reveals the non-inferiority of SI versus FFDM based on BIRADS categorisation [difference between AUC (ΔAUC), -0.014] and lesion visibility (ΔAUC, -0.001) but the differences were not statistically significant (p=0.282 for BIRADS; p=0.961 for lesion visibility). On average, 77.4% of malignant lesions were detected with SI versus 76.5% with FFDM. Sensitivity and specificity of SI are superior to FFDM for malignant lesions scored as BIRADS 5 and breasts categorised as BIRADS 1. SI is not inferior to FFDM when DBT slices are not available during image reading. SI can replace FFDM, reducing the dose by 45%. • Stand-alone SI demonstrated performance not inferior for lesion visibility as compared to FFDM. • Stand-alone SI demonstrated performance not inferior for lesion BIRADS categorisation as compared to FFDM. • Synthetic images provide important dose savings in breast tomosynthesis examinations.

  15. A Meta-Analytic Review of Stand-Alone Interventions to Improve Body Image.

    Directory of Open Access Journals (Sweden)

    Jessica M Alleva

    Full Text Available Numerous stand-alone interventions to improve body image have been developed. The present review used meta-analysis to estimate the effectiveness of such interventions, and to identify the specific change techniques that lead to improvement in body image.The inclusion criteria were that (a the intervention was stand-alone (i.e., solely focused on improving body image, (b a control group was used, (c participants were randomly assigned to conditions, and (d at least one pretest and one posttest measure of body image was taken. Effect sizes were meta-analysed and moderator analyses were conducted. A taxonomy of 48 change techniques used in interventions targeted at body image was developed; all interventions were coded using this taxonomy.The literature search identified 62 tests of interventions (N = 3,846. Interventions produced a small-to-medium improvement in body image (d+ = 0.38, a small-to-medium reduction in beauty ideal internalisation (d+ = -0.37, and a large reduction in social comparison tendencies (d+ = -0.72. However, the effect size for body image was inflated by bias both within and across studies, and was reliable but of small magnitude once corrections for bias were applied. Effect sizes for the other outcomes were no longer reliable once corrections for bias were applied. Several features of the sample, intervention, and methodology moderated intervention effects. Twelve change techniques were associated with improvements in body image, and three techniques were contra-indicated.The findings show that interventions engender only small improvements in body image, and underline the need for large-scale, high-quality trials in this area. The review identifies effective techniques that could be deployed in future interventions.

  16. Preinjector for Linac 1, inside the Faraday cage

    CERN Multimedia

    1974-01-01

    For a description of the Linac 1 preinjector, please see first 7403070X. Here, the view is towards the upper level of the Faraday cage. Far to the right, a technician is peering through the service door. The huge box-shaped cubicle is the electronics platform, at 520 kV potential during operation. The "bull eye" at the left back sits at the top end of the accelerating column (see 7403081X) and houses the ion source with its electronics (see 7403083X). The SAMES generator, providing the 520 kV HV (7403074) sits on the floor and is not visible here.

  17. Sensitivity of BN nano-cages to caffeine and nicotine molecules

    Science.gov (United States)

    Soltani, Alireza; Baei, Mohammad T.; Tazikeh Lemeski, E.; Shahini, Malihe

    2014-12-01

    Adsorption of caffeine and nicotine molecules over B12N12 and B16N16 nano-cages were investigated by using first-principles calculations to define whether BN nano-cages are applicable for filtering or sensing caffeine and nicotine molecules. The chemisorption energy of nicotine molecule on BN nano-cages is very stronger than caffeine molecule. Upon the adsorption of caffeine and nicotine molecules, the electronic properties of the BN nano-cages can be significantly changed, being too much sensitized on the caffeine and nicotine adsorptions.

  18. Evaluation of cage micro-environment of mice housed on various types of bedding materials

    Science.gov (United States)

    Smith, E.; Stockwell, J.D.; Schweitzer, I.; Langley, S.H.; Smith, A.L.

    2004-01-01

    A variety of environmental factors can affect the outcomes of studies using laboratory rodents. One such factor is bedding. Several new bedding materials and processing methods have been introduced to the market in recent years, but there are few reports of their performance. In the studies reported here, we have assessed the cage micro-environment (in-cage ammonia levels, temperature, and humidity) of mice housed on various kinds of bedding and their combinations. We also compared results for bedding supplied as Nestpaks versus loose bedding. We studied C57BL/6J mice (commonly used) and NOD/LtJ mice (heavy soilers) that were maintained, except in one study, in static duplex cages. In general, we observed little effect of bedding type on in-cage temperature or humidity; however, there was considerable variation in ammonia concentrations. The lowest ammonia concentrations occurred in cages housing mice on hardwood bedding or a mixture of corncob and alpha cellulose. In one experiment comparing the micro-environments of NOD/LtJ male mice housed on woodpulp fiber bedding in static versus ventilated caging, we showed a statistically significant decrease in ammonia concentrations in ventilated cages. Therefore, our data show that bedding type affects the micro-environment in static cages and that effects may differ for ventilated cages, which are being used in vivaria with increasing frequency.

  19. Evaluation of cage micro-environment of mice housed on various types of bedding materials.

    Science.gov (United States)

    Smith, Ellen; Stockwell, Jason D; Schweitzer, Isabelle; Langley, Stephen H; Smith, Abigail L

    2004-07-01

    A variety of environmental factors can affect the outcomes of studies using laboratory rodents. One such factor is bedding. Several new bedding materials and processing methods have been introduced to the market in recent years, but there are few reports of their performance. In the studies reported here, we have assessed the cage micro-environment (in-cage ammonia levels, temperature, and humidity) of mice housed on various kinds of bedding and their combinations. We also compared results for bedding supplied as Nestpaks versus loose bedding. We studied C57BL/6J mice (commonly used) and NOD/LtJ mice (heavy soilers) that were maintained, except in one study, in static duplex cages. In general, we observed little effect of bedding type on in-cage temperature or humidity; however, there was considerable variation in ammonia concentrations. The lowest ammonia concentrations occurred in cages housing mice on hardwood bedding or a mixture of corncob and alpha cellulose. In one experiment comparing the micro-environments of NOD/LtJ male mice housed on woodpulp fiber bedding in static versus ventilated caging, we showed a statistically significant decrease in ammonia concentrations in ventilated cages. Therefore, our data show that bedding type affects the micro-environment in static cages and that effects may differ for ventilated cages, which are being used in vivaria with increasing frequency. Copyright 2004 American Association for Laboratory Animal Science

  20. Manipulation of intracellular auxin in a single cell by light with esterase-resistant caged auxins.

    Science.gov (United States)

    Kusaka, Naoyuki; Maisch, Jan; Nick, Peter; Hayashi, Ken-ichiro; Nozaki, Hiroshi

    2009-09-04

    Auxin, a plant hormone, is polar transported from its site of production. This auxin polar transport system establishes an auxin gradient in plant tissue that is necessary for proper plant development. Therefore, the spatial effect of the auxin gradient on plant development is highly important for the understanding of plant auxin responses. Herein we report the design, syntheses and biological properties of esterase-resistant caged auxins. The conventional caging group, 2-nitrobenzyl ester, was found to be enzymatically hydrolyzed in plant cells and released original auxin without photolysis. The esterase-resistant caging group, (2,5-dimethoxyphenyl)(2-nitrobenzyl) ester, (DMPNB) was designed to improve the stability of caged auxins. Three auxins, indole 3-acetic acid, naphthalene 1-acetic acid and 2,4-dichlorophenoxy acetic acid were caged with the DMPNB caging group. DMPNB-caged auxins were inactive within a plant cell until photolysis, but they release auxins with photoirradiation to activate auxin-responsive gene expression. We demonstrated spatial and temporal control of intracellular auxin levels with photoirradiation by using this caged auxin system and were able to photocontrol the physiological auxin response in Arabidopsis plants. Additionally, the photoirradiation of DMPNB-caged auxin within a single cell can manipulate the intracellular auxin level and triggers auxin response.

  1. REINVENTING THE WHEEL: Comparison of Two Wheel Cage Styles for Assessing Mouse Voluntary Running Activity.

    Science.gov (United States)

    Seward, Tanya; Harfmann, Brianna D; Esser, Karyn A; Schroder, Elizabeth A

    2017-12-21

    Voluntary wheel cage assessment of mouse activity is commonly employed in exercise and behavioral research. Currently, no standardization for wheel cages exists resulting in an inability to compare results among data from different labs. The purpose of this study was to determine whether the distance run or average speed data differs depending on the use of two commonly used commercially available wheel cage systems. Two different wheel cages with structurally similar but functionally different wheels (electromechanical switch vs magnetic switch) were compared side-by-side to measure wheel running data differences. Other variables, including enrichment and cage location, were also tested to assess potential impacts on the running wheel data. We found that cages with the electromechanical switch had greater inherent wheel resistance and consistently led to higher greater running distance/day and higher average running speed. Mice rapidly, within 1-2 days, adapted their running behavior to the type of experimental switch used suggesting these running differences are more behavioral than due to intrinsic musculoskeletal, cardiovascular or metabolic limits. The presence of enrichment or location of the cage had no detectable impact on voluntary wheel running. These results demonstrate that mice run differing amounts depending on the type of cage and switch mechanism used and thus, investigators need to report wheel cage type/ wheel resistance and use caution when interpreting distance/speed run across studies.

  2. A stochastic frontier analysis of technical efficiency of fish cage culture in Peninsular Malaysia.

    Science.gov (United States)

    Islam, Gazi Md Nurul; Tai, Shzee Yew; Kusairi, Mohd Noh

    2016-01-01

    Cage culture plays an important role in achieving higher output and generating more export earnings in Malaysia. However, the cost of fingerlings, feed and labour have increased substantially for cage culture in the coastal areas in Peninsular Malaysia. This paper uses farm level data gathered from Manjung, Perak and Kota Tinggi, Johor to investigate the technical efficiency of brackish water fish cage culture using the stochastic frontier approach. The technical efficiency was estimated and specifically the factors affecting technical inefficiencies of fish cage culture system in Malaysia was investigated. On average, 37 percent of the sampled fish cage farms are technically efficient. The results suggest very high degrees of technical inefficiency exist among the cage culturists. This implies that great potential exists to increase fish production through improved efficiency in cage culture management in Peninsular Malaysia. The results indicate that farmers obtained grouper fingerlings from other neighboring countries due to scarcity of fingerlings from wild sources. The cost of feeding for grouper (Epinephelus fuscoguttatus) requires relatively higher costs compared to seabass (Lates calcarifer) production in cage farms in the study areas. Initiatives to undertake extension programmes at the farm level are needed to help cage culturists in utilizing their resources more efficiently in order to substantially enhance their fish production.

  3. A high-precision instrument for analyzing nonlinear dynamic behavior of bearing cage

    International Nuclear Information System (INIS)

    Yang, Z.; Yu, T.; Chen, H.; Li, B.

    2016-01-01

    The high-precision ball bearing is fundamental to the performance of complex mechanical systems. As the speed increases, the cage behavior becomes a key factor in influencing the bearing performance, especially life and reliability. This paper develops a high-precision instrument for analyzing nonlinear dynamic behavior of the bearing cage. The trajectory of the rotational center and non-repetitive run-out (NRRO) of the cage are used to evaluate the instability of cage motion. This instrument applied an aerostatic spindle to support and spin test the bearing to decrease the influence of system error. Then, a high-speed camera is used to capture images when the bearing works at high speeds. A 3D trajectory tracking software TEMA Motion is used to track the spot which marked the cage surface. Finally, by developing the MATLAB program, a Lissajous’ figure was used to evaluate the nonlinear dynamic behavior of the cage with different speeds. The trajectory of rotational center and NRRO of the cage with various speeds are analyzed. The results can be used to predict the initial failure and optimize cage structural parameters. In addition, the repeatability precision of instrument is also validated. In the future, the motorized spindle will be applied to increase testing speed and image processing algorithms will be developed to analyze the trajectory of the cage.

  4. Determining basic parameters of shafts with cage hoisting systems in mines with steep seams

    Energy Technology Data Exchange (ETDEWEB)

    Durov, E.M.

    1982-05-01

    This paper analyzes problems associated with increasing depth of mine shafts in operating coal mines. Schemes of shaft excavation in mines with steep coal seams are analyzed. Removal of mine rock and the ground surface by existing mine shafts is most economical in most cases. Yuzhgiproshakht has investigated a number of hoisting schemes during mine shaft excavation in order to select the optimum shaft diameter which permits shaft reconstruction and deepening to be optimized. The following conditions are analyzed: coal output of a coal mine ranges from 0.9 megatons (Mt) to 1.8 Mt/year, mining depth ranges from 600 m to 1600 m (with intermediary depth of 800, 1000, 1200 and 1400 m also considered). Separate hoisting of coal and rock waste is used. Shaft sinking rate ranges from 10 to 50 m/month. The following hoisting schemes are analyzed: two independent systems which consist of a cage with counterweight, three systems of a cage with counterweight, double cage system and a cage with counterweight. Hoisting schemes are shown in 9 diagrams. Investigations show that a 7 to 8 m diameter of mine shafts is most economic. In mine shafts 7 m in diameter equipped with two cages with counterweights one of the cages is removed to form a free space for the hoisting bucket. In the 8 m shaft equipped with a double cage system and a cage with counterweight the cage with counterweight is removed to form a free place for the hoisting bucket used during shaft excavation.

  5. Protection characteristics of a Faraday cage compromised by lightning burnthrough.

    Energy Technology Data Exchange (ETDEWEB)

    Warne, Larry Kevin; Bystrom, Edward; Jorgenson, Roy Eberhardt; Montoya, Sandra L.; Merewether, Kimball O.; Coats, Rebecca Sue; Martinez, Leonard E.; Jojola, John M.

    2012-01-01

    A lightning flash consists of multiple, high-amplitude but short duration return strokes. Between the return strokes is a lower amplitude, continuing current which flows for longer duration. If the walls of a Faraday cage are made of thin enough metal, the continuing current can melt a hole through the metal in a process called burnthrough. A subsequent return stroke can couple energy through this newly-formed hole. This LDRD is a study of the protection provided by a Faraday cage when it has been compromised by burnthrough. We initially repeated some previous experiments and expanded on them in terms of scope and diagnostics to form a knowledge baseline of the coupling phenomena. We then used a combination of experiment, analysis and numerical modeling to study four coupling mechanisms: indirect electric field coupling, indirect magnetic field coupling, conduction through plasma and breakdown through the hole. We discovered voltages higher than those encountered in the previous set of experiments (on the order of several hundreds of volts).

  6. Regulation of a phage endolysin by disulfide caging.

    Science.gov (United States)

    Kuty, Gabriel F; Xu, Min; Struck, Douglas K; Summer, Elizabeth J; Young, Ry

    2010-11-01

    In contrast to canonical phage endolysins, which require holin-mediated disruption of the membrane to gain access to attack the cell wall, signal anchor release (SAR) endolysins are secreted by the host sec system, where they accumulate in an inactive form tethered to the membrane by their N-terminal SAR domains. SAR endolysins become activated by various mechanisms upon release from the membrane. In its inactive form, the prototype SAR endolysin, Lyz(P1), of coliphage P1, has an active-site Cys covalently blocked by a disulfide bond; activation involves a disulfide bond isomerization driven by a thiol in the newly released SAR domain, unblocking the active-site Cys. Here, we report that Lyz(103), the endolysin of Erwinia phage ERA103, is also a SAR endolysin. Although Lyz(103) does not have a catalytic Cys, genetic evidence suggests that it also is activated by a thiol-disulfide isomerization triggered by a thiol in the SAR domain. In this case, the inhibitory disulfide in nascent Lyz(103) is formed between cysteine residues flanking a catalytic glutamate, caging the active site. Thus, Lyz(P1) and Lyz(103) define subclasses of SAR endolysins that differ in the nature of their inhibitory disulfide, and Lyz(103) is the first enzyme found to be regulated by disulfide bond caging of its active site.

  7. Automated Operant Conditioning in the Mouse Home Cage.

    Science.gov (United States)

    Francis, Nikolas A; Kanold, Patrick O

    2017-01-01

    Recent advances in neuroimaging and genetics have made mice an advantageous animal model for studying the neurophysiology of sensation, cognition, and locomotion. A key benefit of mice is that they provide a large population of test subjects for behavioral screening. Reflex-based assays of hearing in mice, such as the widely used acoustic startle response, are less accurate than operant conditioning in measuring auditory processing. To date, however, there are few cost-effective options for scalable operant conditioning systems. Here, we describe a new system for automated operant conditioning, the Psibox. It is assembled from low cost parts, designed to fit within typical commercial wire-top cages, and allows large numbers of mice to train independently in their home cages on positive reinforcement tasks. We found that groups of mice trained together learned to accurately detect sounds within 2 weeks of training. In addition, individual mice isolated from groups also showed good task performance. The Psibox facilitates high-throughput testing of sensory, motor, and cognitive skills in mice, and provides a readily available animal population for studies ranging from experience-dependent neural plasticity to rodent models of mental disorders.

  8. Individualized choice in prenatal diagnosis : the impact of karyotyping and standalone rapid aneuploidy detection on quality of life

    NARCIS (Netherlands)

    Boormans, E. M. A.; Birnie, E.; Oepkes, D.; Boekkooi, P. F.; Bonsel, G. J.; van Lith, J. M. M.

    2010-01-01

    Objective To assess the reasons and perceptions of women who are offered a choice between karyotyping and standalone rapid aneuploidy detection (RAD) and to compare the impact of both tests on anxiety and health-related quality of life Methods In this prospective comparative study, women undergoing

  9. Analyzing grid extension and stand-alone photovoltaic systems for the cost-effective electrification of Kenya

    NARCIS (Netherlands)

    Zeyringer, Marianne; Pachauri, Shonali; Schmid, Erwin; Schmidt, Johannes; Worrell, Ernst; Morawetz, Ulrich B.

    2015-01-01

    The declaration of 2014-2024 as the Decade of Sustainable Energy for All has catalyzed actions towards achieving universal electricity access. The high costs of building electric infrastructure are a major impediment to improved access, making stand-alone photovoltaic (PV) systems an attractive

  10. Stand-Alone Ethics, Social Responsibility, and Sustainability Course Requirements: A Snapshot from Australia and New Zealand

    Science.gov (United States)

    Rundle-Thiele, Sharyn R.; Wymer, Walter

    2010-01-01

    This article analyzes the extent to which Australian and New Zealand marketing educators use dedicated or stand-alone courses to equip students with alternative views of business. A census of marketing programs in degree-granting universities was conducted. Program brochures were obtained via the Internet and were content analyzed. This study…

  11. 49 CFR 1109.4 - Mandatory mediation in rate cases to be considered under the stand-alone cost methodology.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Mandatory mediation in rate cases to be considered... § 1109.4 Mandatory mediation in rate cases to be considered under the stand-alone cost methodology. (a) A... methodology must engage in non-binding mediation of its dispute with the railroad upon filing a formal...

  12. An improved synchronous reference frame phase-locked loop for stand-alone variable speed constant frequency power generation systems

    DEFF Research Database (Denmark)

    Liu, Yi; Xu, Wei; Ke, Longzhang

    2017-01-01

    The phase-locked loop (PLL) based on conventional synchronous reference frame, i.e. dqPLL, is usually employed in grid-connected variable speed constant frequency (VSCF) power generation systems (PGSs). However, the voltage amplitude drop of stand-alone PGSs is often greater than that of the grid...

  13. Bisphenol A is released from used polycarbonate animal cages into water at room temperature

    Science.gov (United States)

    Howdeshell, Kembra L.; Peterman, Paul H.; Judy, Barbara M.; Taylor, Julia A.; Orazio, Carl E.; Ruhlen, Rachel L.; vom Saal, Frederick S.; Welshons, Wade V.

    2003-01-01

    Bisphenol A (BPA) is a monomer with estrogenic activity that is used in the production of food packaging, dental sealants, polycarbonate plastic, and many other products. The monomer has previously been reported to hydrolyze and leach from these products under high heat and alkaline conditions, and the amount of leaching increases as a function of use. We examined whether new and used polycarbonate animal cages passively release bioactive levels of BPA into water at room temperature and neutral pH. Purified water was incubated at room temperature in new polycarbonate and polysulfone cages and used (discolored) polycarbonate cages, as well as control (glass and used polypropylene) containers. The resulting water samples were characterized with gas chromatography/mass spectrometry (GC/MS) and tested for estrogenic activity using an MCF-7 human breast cancer cell proliferation assay. Significant estrogenic activity, identifiable as BPA by GC/MS (up to 310 micro g/L), was released from used polycarbonate animal cages. Detectable levels of BPA were released from new polycarbonate cages (up to 0.3 micro g/L) as well as new polysulfone cages (1.5 micro g/L), whereas no BPA was detected in water incubated in glass and used polypropylene cages. Finally, BPA exposure as a result of being housed in used polycarbonate cages produced a 16% increase in uterine weight in prepubertal female mice relative to females housed in used polypropylene cages, although the difference was not statistically significant. Our findings suggest that laboratory animals maintained in polycarbonate and polysulfone cages are exposed to BPA via leaching, with exposure reaching the highest levels in old cages.

  14. Outcome of single level anterior cervical discectomy and fusion using nano-hydroxyapatite/polyamide-66 cage

    Directory of Open Access Journals (Sweden)

    Xi Yang

    2014-01-01

    Full Text Available Background: Cages have been widely used for the anterior reconstruction and fusion of cervical spine. Nonmetal cages have become popular due to prominent stress shielding and high rate of subsidence of metallic cages. This study aims to assess fusion with n-HA/PA66 cage following one level anterior cervical discectomy. Materials and Methods: Forty seven consecutive patients with radiculopathy or myelopathy underwent single level ACDF using n-HA/PA66 cage. We measured the segmental lordosis and intervertebral disc height on preoperative radiographs and then calculated the loss of segmental lordosis correction and cage subsidence over followup. Fusion status was evaluated on CT scans. Odom criteria, Japanese Orthopedic Association (JOA and Visual Analog Pain Scales (VAS scores were used to assess the clinical results. Statistically quantitative data were analyzed while Categorical data by χ2 test. Results: Mean correction of segmental lordosis from surgery was 6.9 ± 3.0° with a mean loss of correction of 1.7 ± 1.9°. Mean cage subsidence was 1.2 ± 0.6 mm and the rate of cage subsidence (>2 mm was 2%. The rate of fusion success was 100%. No significant difference was found on clinical or radiographic outcomes between the patients (n=27 who were fused by n-HA/PA66 cage with pure local bone and the ones (n=20 with hybrid bone (local bone associating with bone from iliac crest. Conclusions: The n-HA/PA66 cage is a satisfactory reconstructing implant after anterior cervical discectomy, which can effectively promote bone graft fusion and prevent cage subsidence.

  15. Improving aeration for efficient oxygenation in sea bass sea cages. Blood, brain and gill histology

    Directory of Open Access Journals (Sweden)

    Berillis Panagiotis

    2016-01-01

    Full Text Available An air diffusion based system (Airx was developed to control the dissolved oxygen levels in aquaculture sea cages. The system was introduced and then tested for 37 days in a sea bass sea cage (aerated cage. A second sea bass sea cage, without the AirX, was used as a control. Oxygen levels were measured in both cages at the start of the trial, before the AirX system was introduced, and during the working period of the AirX system. Fish samples were collected 15 days after the AirX system was introduced and at the end of the experiment. Blood smears were prepared and examined microscopically. Erythrocyte major axis, minor axis and area of fish erythrocytes were measured. Leucocyte differentiation was also examined. In the control cage, the fish had significantly larger red blood cells when compared with the red blood cells of the fish in the aerated cage. Histological examination of the gills and brain revealed no morphological differences or alterations between the two groups of fish. This study demonstrated that an air diffuser system could improve the water quality of fish farmed in sea cages and enhance sea bass physiological performance, especially if DO levels fall below 60% oxygen saturation.

  16. A pyrrolo-tetrathiafulvalene cage: Synthesis and X-ray crystal structure

    DEFF Research Database (Denmark)

    Nielsen, Kent A.; Jeppesen, Jan O.; Levillain, Eric

    2002-01-01

    A novel type of tetrathiafulvalene-cage 4 containing three monopyrrolo-tetrathiafulvalene units has been prepared employing a general and efficient synthetic approach. X-ray crystal structure analysis revealed that the cage is able to accommodate solvent molecules within a cavity in the solid state....

  17. Formation of Ti28 ln cages, the highest nuclearity polyoxotitanates (Ln = La, Ce).

    Science.gov (United States)

    Lv, Yaokang; Willkomm, Janina; Leskes, Michal; Steiner, Alexander; King, Timothy C; Gan, Lihua; Reisner, Erwin; Wood, Paul T; Wright, Dominic S

    2012-09-17

    The solvothermal reactions of Ti(OEt)(4) with LnCl(3) (Ln = La, Ce) produced new Ti(28) Ln cages, in which the Ln(3+) ions are coordinated within a metallocrown arrangement, which represents the highest nuclearity cages of this type (see figure). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Recombinant expression and purification of 'virus-like' bacterial encapsulin protein cages

    NARCIS (Netherlands)

    Rurup, W.F.; Cornelissen, Jeroen Johannes Lambertus Maria; Koay, M.S.T.; Orner, Brendan P.

    2015-01-01

    Ultracentrifugation, particularly the use of sucrose or cesium chloride density gradients, is a highly reliable and efficient technique for the purification of virus-like particles and protein cages. Since virus-like particles and protein cages have a unique size compared to cellular macromolecules

  19. Standard methods for maintaining adult Apis mellifera in cages under in vitro laboratory conditions

    NARCIS (Netherlands)

    Williams, G.R.; Alaux, C.; Costa, C.; Csaki, C.; Steen, van der J.J.M.

    2013-01-01

    Adult honey bees are maintained in vitro in laboratory cages for a variety of purposes. For example, researchers may wish to perform experiments on honey bees caged individually or in groups to study aspects of parasitology, toxicology, or physiology under highly controlled conditions, or they may

  20. The Effects of Caging on the Colonization of Fouling Organisms in ...

    African Journals Online (AJOL)

    The effects of caging on the colonization and development of the fouling community in the upper Bonny estuary was studied. The experimental design was such that sets of wooden panels (20x20 cm) were screened with cages constructed with plastic netting while another set was left uncaged. Both sets of panels were ...

  1. Sterilization and strength of 70/30 polylactide cages: e-beam versus ethylene oxide

    NARCIS (Netherlands)

    Smit, Theo H.; Thomas, Kevin A.; Hoogendoorn, Roel J. W.; Strijkers, Gustav J.; Helder, Marco N.; Wuisman, Paul I. J. M.

    2007-01-01

    In vitro and in vivo studies on the degradation of 70/30 poly(L,DL-lactide) (PLDLLA) cages. To evaluate the effect of e-beam and ethylene oxide sterilization on degradation and strength. e-beam-sterilized PLDLLA cages were shown to maintain mechanical strength for at least 6 months during

  2. Animal Welfare and Food Safety Aspects of Confining Broiler Chickens to Cages.

    Science.gov (United States)

    Shields, Sara; Greger, Michael

    2013-05-13

    In most areas of the world, broiler chickens are raised in floor systems, but cage confinement is becoming more common. The welfare of broiler chickens in cages is affected by movement restriction, poor bone strength due to lack of exercise, and prevention of key behavioral patterns such as dustbathing and ground scratching. Cages for broiler chickens also have a long history of causing skin and leg conditions that could further compromise welfare, but a lack of controlled studies makes it difficult to draw conclusions about newer cage designs. Cage environments are usually stocked at a higher density than open floor systems, and the limited studies available suggest that caging may lead to increased levels of fear and stress in the birds. Further, birds reared on the floor appear less likely to harbor and shed Salmonella, as litter may serve as a seeding agent for competitive exclusion by other microorganisms. Cages for laying hens used in egg production have met with substantial opposition due to welfare concerns and caging broiler chickens will likely be subject to the same kinds of social disapproval.

  3. Effects of housing system (outdoor vs cages) and age of laying hens on egg characteristics

    NARCIS (Netherlands)

    Brand, van den H.; Parmentier, H.K.; Kemp, B.

    2004-01-01

    1. Effects of two housing systems (cages vs outdoor) on external and internal egg characteristics were investigated. 2. In total 785 eggs from three different lines in cages and 268 eggs from outdoor-housed layers were examined for egg weight, albumen, yolk and shell content, albumen height and pH,

  4. Effects of cage fish culture on water quality and selected biological ...

    African Journals Online (AJOL)

    Growing of fish in cages is currently practiced in Uganda and was first introduced in northern Lake Victoria in 2010. An environment monitoring study was undertaken at Source of the Nile, a private cage fish farm, in Napoleon gulf, northern Lake Victoria. In-situ measurements of key environmental (temperature, dissolved ...

  5. Self-Assembly, Guest Capture, and NMR Spectroscopy of a Metal-Organic Cage in Water

    Science.gov (United States)

    Go, Eun Bin; Srisuknimit, Veerasak; Cheng, Stephanie L.; Vosburg, David A.

    2016-01-01

    A green organic-inorganic laboratory experiment has been developed in which students prepare a self-assembling iron cage in D[subscript 2]O at room temperature. The tetrahedral cage captures a small, neutral molecule such as cyclohexane or tetrahydrofuran. [Superscript 1]H NMR analysis distinguishes captured and free guests through diagnostic…

  6. Load-following mode control of a standalone renewable/fuel cell hybrid power source

    International Nuclear Information System (INIS)

    Bizon, Nicu

    2014-01-01

    Highlights: • A FC hybrid power source (HPS) fed by renewable energy sources (RESs) is proposed. • The fuel cell (FC) operates as a backup to RESs based on the load-following strategy. • The energy storage device (ESS) will operate in charge-sustaining mode during a load cycle. • The ESS optimal design considers the peaks of RESs power and the imposed SOC window. • The FC/RES/ESS HPS is ideal to be used for standalone plug-in charge station. - Abstract: A hybrid power source (HPS), fed by renewable energy sources (RESs) and fuel cell (FC) sources, with an energy storage device (ESS) to be suitable for distributed generation (DG) applications, is proposed herein. The RESs could be a combination of photovoltaic (PV) panels and wind turbines (WT) based on common DC-bus, which are used as the primary DC source. The FC operates as a backup, feeding only the insufficiency power from the RESs based on the load-following strategy. The battery/ultracapacitor hybrid ESS operates as an auxiliary source for supplying the power deficit based on dynamic power balance strategy (the transient power – mainly via the ultracapacitors stack, and the steady-state power – mainly via the FC and batteries stack). If the FC stack is designed and operates based on average load-following strategy, then the ESS will operate in charge-sustaining mode during a load cycle. This feature permits to optimize the batteries stack capacity and extend its life time as well. The ultracapacitors stack can be designed considering the peaks of RESs power on DC-bus and the imposed window for its state-of-charge (SOC). This FC/RES/ESS HPS is ideal to be used for standalone plug-in charge station (PCS) or as DG system grid connected. In the last case, which is not analyzed here, the energy management unit (EMU) that communicates with smart grid will establish the moments to match the HPS power demand with grid supply availability, stabilizing the grid. Using load and RES power profiles that have

  7. Five-year durability of stand-alone interspinous process decompression for lumbar spinal stenosis

    Directory of Open Access Journals (Sweden)

    Nunley PD

    2017-09-01

    Full Text Available Pierce D Nunley,1 Vikas V Patel,2 Douglas G Orndorff,3 William F Lavelle,4 Jon E Block,5 Fred H Geisler6 1Spine Institute of Louisiana, Shreveport, LA, 2The Spine Center, University of Colorado Hospital, Denver, CO, 3Spine Colorado, Mercy Regional Hospital, Durango, CO, 4Upstate Bone and Joint Center, East Syracuse, NY, 5Independent Consultant, San Francisco, CA, 6Independent Consultant, Chicago, IL, USA Background: Lumbar spinal stenosis is the most common indication for spine surgery in older adults. Interspinous process decompression (IPD using a stand-alone spacer that functions as an extension blocker offers a minimally invasive treatment option for intermittent neurogenic claudication associated with spinal stenosis.Methods: This study evaluated the 5-year clinical outcomes for IPD (Superion® from a randomized controlled US Food and Drug Administration (FDA noninferiority trial. Outcomes included Zurich Claudication Questionnaire (ZCQ symptom severity (ss, physical function (pf, and patient satisfaction (ps subdomains, leg and back pain visual analog scale (VAS, and Oswestry Disability Index (ODI.Results: At 5 years, 84% of patients (74 of 88 demonstrated clinical success on at least two of three ZCQ domains. Individual ZCQ domain success rates were 75% (66 of 88, 81% (71 of 88, and 90% (79 of 88 for ZCQss, ZCQpf, and ZCQps, respectively. Leg and back pain success rates were 80% (68 of 85 and 65% (55 of 85, respectively, and the success rate for ODI was 65% (57 of 88. Percentage improvements over baseline were 42%, 39%, 75%, 66%, and 58% for ZCQss, ZCQpf, leg and back pain VAS, and ODI, respectively (all P<0.001. Within-group effect sizes were classified as very large for four of five clinical outcomes (ie, >1.0; all P<0.0001. Seventy-five percent of IPD patients were free from reoperation, revision, or supplemental fixation at their index level at 5 years.Conclusion: After 5 years of follow-up, IPD with a stand-alone spacer provides

  8. Addressing the challenges of standalone multi-core simulations in molecular dynamics

    Science.gov (United States)

    Ocaya, R. O.; Terblans, J. J.

    2017-07-01

    Computational modelling in material science involves mathematical abstractions of force fields between particles with the aim to postulate, develop and understand materials by simulation. The aggregated pairwise interactions of the material's particles lead to a deduction of its macroscopic behaviours. For practically meaningful macroscopic scales, a large amount of data are generated, leading to vast execution times. Simulation times of hours, days or weeks for moderately sized problems are not uncommon. The reduction of simulation times, improved result accuracy and the associated software and hardware engineering challenges are the main motivations for many of the ongoing researches in the computational sciences. This contribution is concerned mainly with simulations that can be done on a "standalone" computer based on Message Passing Interfaces (MPI), parallel code running on hardware platforms with wide specifications, such as single/multi- processor, multi-core machines with minimal reconfiguration for upward scaling of computational power. The widely available, documented and standardized MPI library provides this functionality through the MPI_Comm_size (), MPI_Comm_rank () and MPI_Reduce () functions. A survey of the literature shows that relatively little is written with respect to the efficient extraction of the inherent computational power in a cluster. In this work, we discuss the main avenues available to tap into this extra power without compromising computational accuracy. We also present methods to overcome the high inertia encountered in single-node-based computational molecular dynamics. We begin by surveying the current state of the art and discuss what it takes to achieve parallelism, efficiency and enhanced computational accuracy through program threads and message passing interfaces. Several code illustrations are given. The pros and cons of writing raw code as opposed to using heuristic, third-party code are also discussed. The growing trend

  9. Charactrization of a Li-ion battery based stand-alone a-Si photovoltaic system

    Science.gov (United States)

    Hamid Vishkasougheh, Mehdi; Tunaboylu, Bahadir

    2014-11-01

    The number of photovoltaic (PV) system installations is increasing rapidly. As more people learn about this versatile and often cost-effective power option, this trend will accelerate. This document presents a recommended design for a battery based stand-alone photovoltaic system (BSPV). BSPV system has the ability to be applied in different areas, including warning signals, lighting, refrigeration, communication, residential water pumping, remote sensing, and cathodic protection. The presented calculation method gives a proper idea for a system sizing technique. Based on application load, different scenarios are possible for designing a BSPV system. In this study, a battery based stand-alone system was designed. The electricity generation part is three a-Si panels, which are connected in parallel, and for the storage part LFP (lithium iron phosphate) battery was used. The high power LFP battery packs are 40 cells each 8S5P (configured 8 series 5 parallel). Each individual pack weighs 0.5 kg and is 25.6 V. In order to evaluate the efficiency of a-Si panels with respect to the temperature and the solar irradiation, cities of Istanbul, Ankara and Adana in Turkey were selected. Temperature and solar irradiation were gathered from reliable sources and by using translation equations, current and voltage output of panels were calculated. As a result of these calculations, current and energy outputs were computed by considering an average efficient solar irradiation time value per day in Turkey. The calculated power values were inserted to a battery cycler system, and the behavior of high power LFP batteries in a time sequence of 7.2 h was evaluated. The charging and discharging cycles were obtained and their behavior was discussed. According to the results, Istanbul has the lowest number of peak month's energy, it followed by Ankara, and ultimately Adana has the highest number of peak months and energy storage. It was observed during the tests that values up to 4 A was

  10. Multi-objective analytical model for optimal sizing of stand-alone photovoltaic water pumping systems

    International Nuclear Information System (INIS)

    Olcan, Ceyda

    2015-01-01

    Highlights: • An analytical optimal sizing model is proposed for PV water pumping systems. • The objectives are chosen as deficiency of power supply and life-cycle costs. • The crop water requirements are estimated for a citrus tree yard in Antalya. • The optimal tilt angles are calculated for fixed, seasonal and monthly changes. • The sizing results showed the validity of the proposed analytical model. - Abstract: Stand-alone photovoltaic (PV) water pumping systems effectively use solar energy for irrigation purposes in remote areas. However the random variability and unpredictability of solar energy makes difficult the penetration of PV implementations and complicate the system design. An optimal sizing of these systems proves to be essential. This paper recommends a techno-economic optimization model to determine optimally the capacity of the components of PV water pumping system using a water storage tank. The proposed model is developed regarding the reliability and cost indicators, which are the deficiency of power supply probability and life-cycle costs, respectively. The novelty is that the proposed optimization model is analytically defined for two-objectives and it is able to find a compromise solution. The sizing of a stand-alone PV water pumping system comprises a detailed analysis of crop water requirements and optimal tilt angles. Besides the necessity of long solar radiation and temperature time series, the accurate forecasts of water supply needs have to be determined. The calculation of the optimal tilt angle for yearly, seasonally and monthly frequencies results in higher system efficiency. It is, therefore, suggested to change regularly the tilt angle in order to maximize solar energy output. The proposed optimal sizing model incorporates all these improvements and can accomplish a comprehensive optimization of PV water pumping systems. A case study is conducted considering the irrigation of citrus trees yard located in Antalya, Turkey

  11. Solid state and aqueous behavior of uranyl peroxide cage clusters

    Science.gov (United States)

    Pellegrini, Kristi Lynn

    Uranyl peroxide cage clusters include a large family of more than 50 published clusters of a variety of sizes, which can incorporate various ligands including pyrophosphate and oxalate. Previous studies have reported that uranyl clusters can be used as a method to separate uranium from a solid matrix, with potential applications in reprocessing of irradiated nuclear fuel. Because of the potential applications of these novel structures in an advanced nuclear fuel cycle and their likely presence in areas of contamination, it is important to understand their behavior in both solid state and aqueous systems, including complex environments where other ions are present. In this thesis, I examine the aqueous behavior of U24Pp 12, as well as aqueous cluster systems with added mono-, di-, and trivalent cations. The resulting solutions were analyzed using dynamic light scattering and ultra-small angle X-ray scattering to evaluate the species in solution. Precipitates of these systems were analyzed using powder X-ray diffraction, X-ray fluorescence spectrometry, and Raman spectroscopy. The results of these analyses demonstrate the importance of cation size, charge, and concentration of added cations on the aqueous behavior of uranium macroions. Specifically, aggregates of various sizes and shapes form rapidly upon addition of cations, and in some cases these aggregates appear to precipitate into an X-ray amorphous material that still contains U24Pp12 clusters. In addition, I probe aggregation of U24Pp12 and U60, another uranyl peroxide cage cluster, in mixed solvent water-alcohol systems. The aggregation of uranyl clusters in water-alcohol systems is a result of hydrogen bonding with polar organic molecules and the reduction of the dielectric constant of the system. Studies of aggregation of uranyl clusters also allow for comparison between the newer uranyl polyoxometalate family and century-old transition metal polyoxometalates. To complement the solution studies of uranyl

  12. Effects of manual rib cage compressions on expiratory flow and mucus clearance during mechanical ventilation.

    Science.gov (United States)

    Martí, Joan Daniel; Li Bassi, Gianluigi; Rigol, Montserrat; Saucedo, Lina; Ranzani, Otavio Tavares; Esperatti, Mariano; Luque, Nestor; Ferrer, Miquel; Vilaro, Jordi; Kolobow, Theodor; Torres, Antoni

    2013-03-01

    We investigated the effects of two different types of manual rib cage compression on expiratory flow and mucus clearance during prolonged mechanical ventilation in pigs. Prospective randomized animal study. Animal research facility, University of Barcelona, Spain. Nine healthy pigs. Pigs were tracheally intubated, sedated, paralyzed, and mechanically ventilated. The animals were prone on a surgical bed in the anti-Trendelenburg position. The experiments were carried out at approximately 60 and 80 hrs from the beginning of mechanical ventilation. Two types of manual rib cage compressions were tested: Hard and brief rib cage compressions synchronized with early expiratory phase (hard manual rib cage compression) and soft and gradual rib cage compressions applied during the late expiratory phase (soft manual rib cage compression). The interventions were randomly applied for 15min with a 15-min interval between treatments. Respiratory flow and mucus movement were assessed during the interventions. Respiratory mechanics and hemodynamics were assessed prior to and after the interventions. Peak expiratory flow increased to 60.1±7.1L/min in comparison to 51.2±4.6L/min without treatment (p < 0.0015) and 48.7±4.3L/min with soft manual rib cage compression (p = 0.0002). Similarly, mean expiratory flow increased to 28.4±5.2L/min during hard manual rib cage compression vs. 15.9±2.2 and 16.6±2.8L/min without treatment and soft manual rib cage compression, respectively (p = 0.0006). During hard manual rib cage compression, mucus moved toward the glottis (1.01 ± 2.37mm/min); conversely, mucus moved toward the lungs during no treatment and soft manual rib cage compression, -0.28 ± 0.61 and -0.15±0.95mm/min, respectively (p = 0.0283). Soft manual rib cage compression slightly worsened static lung elastance and cardiac output (p = 0.0391). Hard manual rib cage compression improved mucus clearance in animals positioned in the anti-Trendelenburg position. The technique

  13. Particulate waste outflow from fish-farming cages. How much is uneaten feed?

    Science.gov (United States)

    Ballester-Moltó, M; Sanchez-Jerez, P; Cerezo-Valverde, J; Aguado-Giménez, F

    2017-06-15

    Particulate wastes drive benthic organic enrichment from cage fish farming. Differentiation between faeces and uneaten feed estimates at cage level are of great value to both economize the feeding process and reduce waste. This study estimates the particulate waste outflowing cages at different depths and orientations, and the wasted feed component by combining in situ measurements and modelling. Particulate matter flux (PMF) was greater vertically through the cage bottoms (60.89%), but lateral outflow was also substantial (39.11%). PMF occurs all around the cages, and the influence of the mainstream current was low. Wasted feed was greatly variable, reaching high values (about 50% of supplied feed. The self-application of feed wastage monitoring and estimates by fish farmers is recommended to improve sustainability. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Parameters estimation of squirrel-cage induction motors using ANN and ANFIS

    Directory of Open Access Journals (Sweden)

    Mehdi Ahmadi Jirdehi

    2016-03-01

    Full Text Available In the transient behavior analysis of a squirrel-cage induction motor, the parameters of the single-cage and double-cage models are studied. These parameters are usually hard to obtain. This paper presents two new methods to predict the induction motor parameters in the single-cage and double-cage models based on artificial neural network (ANN and adaptive neuro-fuzzy inference system (ANFIS. For this purpose, the experimental data (manufacturer data of 20 induction motors with the different power are used. The experimental data are including of the starting torque and current, maximum torque, full load sleep, efficiency, rated active power and reactive power. The obtained results from the proposed ANN and ANFIS models are compared with each other and with the experimental data, which show a good agreement between the predicted values and the experimental data. But the proposed ANFIS model is more accurate than the proposed ANN model.

  15. The effect of cage size on reproductive performance and behavior of C57BL/6 mice.

    Science.gov (United States)

    Whitaker, Julia; Moy, Sheryl S; Saville, Benjamin R; Godfrey, Virginia; Nielsen, Judith; Bellinger, Dwight; Bradfield, John

    2007-11-01

    Scientific research has yet to conclusively determine the optimal cage size for mice. The authors examined the effect of cage size on mouse breeding performance and on offspring behavior, which can serve as indications of overall well-being. They housed breeding trios of C57BL/6Tac mice in standard or large individually ventilated cages and measured four reproductive parameters: litter size; litter survival to weaning age; average pup weight at 7, 14 and 21 days; and the number of days between litter births. They investigated the behavior of a subset of male and female pups from parents housed in cages of each size in the elevated plus maze test, the open field assay and the acoustic startle test. Cage size had no significant effect on any of the reproductive parameters measured and few or inconsistent effects on behavior in weaned pups.

  16. Effect of small cage guests on hydrogen bonding of tetrahydrofuran in binary structure II clathrate hydrates.

    Science.gov (United States)

    Alavi, Saman; Ripmeester, John A

    2012-08-07

    Molecular dynamics simulations of the pure structure II tetrahydrofuran clathrate hydrate and binary structure II tetrahydrofuran clathrate hydrate with CO(2), CH(4), H(2)S, and Xe small cage guests are performed to study the effect of the shape, size, and intermolecular forces of the small cages guests on the structure and dynamics of the hydrate. The simulations show that the number and nature of the guest in the small cage affects the probability of hydrogen bonding of the tetrahydrofuran guest with the large cage water molecules. The effect on hydrogen bonding of tetrahydrofuran occurs despite the fact that the guests in the small cage do not themselves form hydrogen bonds with water. These results indicate that nearest neighbour guest-guest interactions (mediated through the water lattice framework) can affect the clathrate structure and stability. The implications of these subtle small guest effects on clathrate hydrate stability are discussed.

  17. Two-piece ALIF cage optimizes the bone-implant interface in a 360° setting.

    Science.gov (United States)

    Wilke, Hans-Joachim; Volkheimer, David; Robie, Bruce; Christensen, Finn B

    2017-11-01

    Clinical research has documented that cage subsidence and the loss of balance correction is a significant complication related to spinal fusion. Subsidence is a multifactorial complication, where implant design is one important element. The aim of the study is to compare the rigidity and bone-implant relative motion of segments treated with either a conventional one-piece ALIF cage versus a two-piece ALIF cage, which adapts in situ and permits 7°-21° of lordosis. Seven lumbosacral (L3-S1) human cadaver specimens were tested in a universal spine tester in the intact condition, the specimens instrumented with a two-piece ALIF cage (Statur ® -L, FBC Device, Denmark) and a one-piece ALIF cage (Pezo™-A, Ulrich GmbH & Co. KG., Germany), both supplemented with a pedicle screw system using pure moments of ±7.5 Nm in three principal motion directions. For assessment of the bone-implant interface, fluoroscopic videos were captured during motion and 3D motion was measured using an optical motion capturing system. Significantly less motion at the implant-endplate interface was found for the two-piece cage (1.0° ± 0.6°) in comparison to the one-piece cage (4.2° ± 1.7°) in flexion/extension. No significant differences in segment rigidity were found between the one-piece and two-piece cages in the 360° setup, while both configurations significantly reduced the range of motion compared to the intact condition (p one-piece ALIF cages, the two-piece cage concept reduced the relative motion at the bone-implant interface without compromising stability.

  18. Specific Internalisation of Gold Nanoparticles into Engineered Porous Protein Cages via Affinity Binding.

    Science.gov (United States)

    Paramelle, David; Peng, Tao; Free, Paul; Fernig, David G; Lim, Sierin; Tomczak, Nikodem

    2016-01-01

    Porous protein cages are supramolecular protein self-assemblies presenting pores that allow the access of surrounding molecules and ions into their core in order to store and transport them in biological environments. Protein cages' pores are attractive channels for the internalisation of inorganic nanoparticles and an alternative for the preparation of hybrid bioinspired nanoparticles. However, strategies based on nanoparticle transport through the pores are largely unexplored, due to the difficulty of tailoring nanoparticles that have diameters commensurate with the pores size and simultaneously displaying specific affinity to the cages' core and low non-specific binding to the cages' outer surface. We evaluated the specific internalisation of single small gold nanoparticles, 3.9 nm in diameter, into porous protein cages via affinity binding. The E2 protein cage derived from the Geobacillus stearothermophilus presents 12 pores, 6 nm in diameter, and an empty core of 13 nm in diameter. We engineered the E2 protein by site-directed mutagenesis with oligohistidine sequences exposing them into the cage's core. Dynamic light scattering and electron microscopy analysis show that the structures of E2 protein cages mutated with bis- or penta-histidine sequences are well conserved. The surface of the gold nanoparticles was passivated with a self-assembled monolayer made of a mixture of short peptidols and thiolated alkane ethylene glycol ligands. Such monolayers are found to provide thin coatings preventing non-specific binding to proteins. Further functionalisation of the peptide coated gold nanoparticles with Ni2+ nitrilotriacetic moieties enabled the specific binding to oligohistidine tagged cages. The internalisation via affinity binding was evaluated by electron microscopy analysis. From the various mutations tested, only the penta-histidine mutated E2 protein cage showed repeatable and stable internalisation. The present work overcomes the limitations of currently

  19. Resonance Spectra of Caged Stringy Black Hole and Its Spectroscopy

    Directory of Open Access Journals (Sweden)

    I. Sakalli

    2015-01-01

    quasinormal mode (QNM frequencies, is used to investigate the entropy/area spectra of the Garfinkle–Horowitz–Strominger black hole (GHSBH. Instead of the ordinary QNMs, we compute the boxed QNMs (BQNMs that are the characteristic resonance spectra of the confined scalar fields in the GHSBH geometry. For this purpose, we assume that the GHSBH has a confining cavity (mirror placed in the vicinity of the event horizon. We then show how the complex resonant frequencies of the caged GHSBH are computed using the Bessel differential equation that arises when the scalar perturbations around the event horizon are considered. Although the entropy/area is characterized by the GHSBH parameters, their quantization is shown to be independent of those parameters. However, both spectra are equally spaced.

  20. Magnetotactic Bacterial Cages as Safe and Smart Gene Delivery Vehicles

    KAUST Repository

    Alsaiari, Shahad K.

    2016-07-27

    In spite of the huge advances in the area of synthetic carriers, their efficiency still poorly compares to natural vectors. Herein, we report the use of unmodified magnetotactic bacteria as a guidable delivery vehicle for DNA functionalized gold nanoparticles (AuNPs). High cargo loading is established under anaerobic conditions (bacteria is alive) through endocytosis where AuNPs are employed as transmembrane proteins mimics (facilitate endocytosis) as well as imaging agents to verify and quantify loading and release. The naturally bio-mineralized magnetosomes, within the bacteria, induce heat generation inside bacteria through magnetic hyperthermia. Most importantly after exposing the system to air (bacteria is dead) the cell wall stays intact providing an efficient bacterial vessel. Upon incubation with THP-1 cells, the magnetotactic bacterial cages (MBCs) adhere to the cell wall and are directly engulfed through the phagocytic activity of these cells. Applying magnetic hyperthermia leads to the dissociation of the bacterial microcarrier and eventual release of cargo.

  1. CAGE Analysis of China’s Trade Globalization

    Directory of Open Access Journals (Sweden)

    Emmanuel Olusegun STOBER

    2014-06-01

    Full Text Available Gravity model of international trade states that trade interaction between two countries is in direct proportion to their size measured by Gross Domestic Product and in inverse proportion to the geographic distance. Conley and Ligon (2001 argued that the relevant economic distance between countries is often not the geographic distance. Thus, this study uses original datasets on economic distance to structure observed variations, to decompose the multidimensional CAGE distance framework of globalization derived from the Newton’s Law of gravitation as it applies to China’s international interaction, to evaluate bilateral trade patterns in identifying and prioritizing the importance of cross-border flows and differences that accounted for the development of China’s global strategies. This study confirms that distance must be accounted for in the decision making of any country’s globalization process or any firm’s global expansion as the effects on cross-border economic activities are enormous.

  2. Gaiola de metabolismo para equinos Metabolism cage for horses

    Directory of Open Access Journals (Sweden)

    Dorinha Miriam Silber Schmidt Vitti

    2000-05-01

    Full Text Available A gaiola de metabolismo, modelo proposto neste trabalho, foi construida na Seção de Oficina da FCAV-Unesp, Jaboticabal-SP e utilizada no Laboratório de Ciências Animais do Cena-USP, Piracicaba-SP. Este equipamento permite alojar eqüinos machos com idade a partir do desmame. Os animais foram treinados (condicionados diariamente a permanecer na gaiola de metabolismo por um período de aproximadamente 30 dias antes do início do experimento. O material necessário e a construção de uma gaiola metabólica para eqüinos machos é descrita e ilustrada. A estrutura principal da gaiola (2,68 m de comprimento x 0,80 m de largura x 2,02 m de altura é constituida por canos de metal de duas polegadas e todas as unidades de apoio - tábuas do piso, grade de urina, bebedouro, comedouro, bandeja coletora de urina e barras de contenção - estão fixas à estrutura principal de modo a serem removidas desta, faciltando o manejo e a limpeza do equipamento. O equipamento foi projetado para alojar animais de vários tamanhos e também para ser efetiva na coleta total de fezes e urina e no fornecimento de alimento e água. Os animais permaneceram em pé durante todo o período de confinamento, sem contudo ter havido a ocorrência de edemas graves nos membros. O modelo proposto foi testado em experimentos de metabolismo de fósforo utilizando-se radioisótopos.The metabolism cage here proposed was built at FCAV-Unesp, Jaboticabal, state of São Paulo, Brazil, and used in the Animal Science Laboratory at Cena-USP, Piracicaba, state of São Paulo, Brazil. The equipment allows to host male horses from weaning to adult age. Before starting the experiment, the animals were daily conditioned for a 30-day period to remain in the cage. The necessary material and the building process of the horse metabolic cage are described and illustrated. The main structure of the cage (2.68m long x 0.80 m wide x 2.02 m high was made of 2-inch-diameter metal tube, and all the

  3. Chemistry and Biology of the Caged Garcinia Xanthones

    Science.gov (United States)

    Chantarasriwong, Oraphin; Batova, Ayse; Chavasiri, Warinthorn

    2011-01-01

    Natural products have been a great source of many small molecule drugs for various diseases. In spite of recent advances in biochemical engineering and fermentation technologies that allow us to explore microorganisms and the marine environment as alternative sources of drugs, more than 70% of the current small molecule therapeutics derive their structures from plants used in traditional medicine. Natural-product-based drug discovery relies heavily on advances made in the sciences of biology and chemistry. Whereas biology aims to investigate the mode of action of a natural product, chemistry aims to overcome challenges related to its supply, bioactivity, and target selectivity. This review summarizes the explorations of the caged Garcinia xanthones, a family of plant metabolites that possess a unique chemical structure, potent bioactivities, and a promising pharmacology for drug design and development. PMID:20648491

  4. Performance Analysis of a Brushless Double Fed Cage Induction Generator

    Energy Technology Data Exchange (ETDEWEB)

    Ruencos, F. [WEG S.A., Jaragua do Sul (Brazil); Carlson, R.; Oliveira, A.M.; Kuo-Peng, P.; Sadowski, N. [GRUCAD-UFSC, Florianopolis (Brazil)

    2004-07-01

    This paper analyses design and performance aspects of a brushless double fed cage induction generator as an economic and technical alternative to the classical wound rotor induction generator used in wind power generation. It focuses firstly on the machine operational characteristics and main design criteria and secondly on steady state and dynamic analytical and numerical models for efficient prediction of machine behavior. The analytical dynamic model is obtained by transforming the equations written in machine variables into equations written in an arbitrary reference frame. In the finite element approach the electrical machine is modeled in a 2D domain, using the Maxwell equations to formulate the field behavior and the FE method to discretize the domain of study. A prototype was built and tested to validate the simulation models and to verify the design criteria.

  5. Solar photovoltaic applications seminar: design, installation and operation of small, stand-alone photovoltaic power systems

    Energy Technology Data Exchange (ETDEWEB)

    1980-07-01

    This seminar material was developed primarily to provide solar photovoltaic (PV) applied engineering technology to the Federal community. An introduction to photoconductivity, semiconductors, and solar photovoltaic cells is included along with a demonstration of specific applications and application identification. The seminar details general systems design and incorporates most known information from industry, academia, and Government concerning small solar cell power system design engineering, presented in a practical and applied manner. Solar PV power system applications involve classical direct electrical energy conversion and electric power system analysis and synthesis. Presentations and examples involve a variety of disciplines including structural analysis, electric power and load analysis, reliability, sizing and optimization; and, installation, operation and maintenance. Four specific system designs are demonstrated: water pumping, domestic uses, navigational and aircraft aids, and telecommunications. All of the applications discussed are for small power requirement (under 2 kilowatts), stand-alone systems to be used in remote locations. Also presented are practical lessons gained from currently installed and operating systems, problems at sites and their resolution, a logical progression through each major phase of system acquisition, as well as thorough design reviews for each application.

  6. Comparison of two stand-alone CADe systems at multiple operating points

    Science.gov (United States)

    Sahiner, Berkman; Chen, Weijie; Pezeshk, Aria; Petrick, Nicholas

    2015-03-01

    Computer-aided detection (CADe) systems are typically designed to work at a given operating point: The device displays a mark if and only if the level of suspiciousness of a region of interest is above a fixed threshold. To compare the standalone performances of two systems, one approach is to select the parameters of the systems to yield a target false-positive rate that defines the operating point, and to compare the sensitivities at that operating point. Increasingly, CADe developers offer multiple operating points, which necessitates the comparison of two CADe systems involving multiple comparisons. To control the Type I error, multiple-comparison correction is needed for keeping the family-wise error rate (FWER) less than a given alpha-level. The sensitivities of a single modality at different operating points are correlated. In addition, the sensitivities of the two modalities at the same or different operating points are also likely to be correlated. It has been shown in the literature that when test statistics are correlated, well-known methods for controlling the FWER are conservative. In this study, we compared the FWER and power of three methods, namely the Bonferroni, step-up, and adjusted step-up methods in comparing the sensitivities of two CADe systems at multiple operating points, where the adjusted step-up method uses the estimated correlations. Our results indicate that the adjusted step-up method has a substantial advantage over other the two methods both in terms of the FWER and power.

  7. Stand-alone excitation synchronous wind power generators with power flow management strategy

    Directory of Open Access Journals (Sweden)

    Tzuen-Lih Chern

    2014-09-01

    Full Text Available This study presents a stand-alone excitation synchronous wind power generator (SESWPG with power flow management strategy (PFMS. The rotor speed of the excitation synchronous generator tracks the utility grid frequency by using servo motor tracking technologies. The automatic voltage regulator governs the exciting current of generator to achieve the control goals of stable voltage. When wind power is less than the needs of the consumptive loading, the proposed PFMS increases motor torque to provide a positive power output for the loads, while keeping the generator speed constant. Conversely, during the periods of wind power greater than output loads, the redundant power of generator production is charged to the battery pack and the motor speed remains constant with very low power consumption. The advantage of the proposed SESWPG is that the generator can directly output stable alternating current (AC electricity without using additional DC–AC converters. The operation principles with software simulation for the system are described in detail. Experimental results of a laboratory prototype are shown to verify the feasibility of the system.

  8. Improvement of Maximum Power Point Tracking Perturb and Observe Algorithm for a Standalone Solar Photovoltaic System

    Directory of Open Access Journals (Sweden)

    MUHAMMAD MATEEN AFZAL AWAN

    2017-07-01

    Full Text Available Extraction of maximum power from PV (Photovoltaic cell is necessary to make the PV system efficient. Maximum power can be achieved by operating the system at MPP (Maximum Power Point (taking the operating point of PV panel to MPP and for this purpose MPPT (Maximum Power Point Trackers are used. There are many tracking algorithms/methods used by these trackers which includes incremental conductance, constant voltage method, constant current method, short circuit current method, PAO (Perturb and Observe method, and open circuit voltage method but PAO is the mostly used algorithm because it is simple and easy to implement. PAO algorithm has some drawbacks, one is low tracking speed under rapid changing weather conditions and second is oscillations of PV systems operating point around MPP. Little improvement is achieved in past papers regarding these issues. In this paper, a new method named ?Decrease and Fix? method is successfully introduced as improvement in PAO algorithm to overcome these issues of tracking speed and oscillations. Decrease and fix method is the first successful attempt with PAO algorithm for stability achievement and speeding up of tracking process in photovoltaic system. Complete standalone photovoltaic system?s model with improved perturb and observe algorithm is simulated in MATLAB Simulink

  9. Control of a Stand-Alone Variable Speed Wind Energy Supply System †

    Directory of Open Access Journals (Sweden)

    Mohamed M. Hamada

    2013-04-01

    Full Text Available This paper presents a simple control strategy for the operation of a variable speed stand-alone wind turbine with a permanent magnet synchronous generator (PMSG. The PMSG is connected to a three phase resistive load through a switch mode rectifier and a voltage source inverter. Control of the generator side converter is used to achieve maximum power extraction from the available wind power. Control of the DC-DC bidirectional buck-boost converter, which is connected between batteries bank and DC-link voltage, is used to maintain the DC-link voltage at a constant value. It is also used to make the batteries bank stores the surplus of wind energy and supplies this energy to the load during a wind power shortage. The load side voltage source inverter uses a relatively complex vector control scheme to control the output load voltage in terms of amplitude and frequency. The control strategy works under wind speed variation as well as with variable load. Extensive simulation results have been performed using MATLAB/SIMULINK.

  10. Can aqueous hydrogen peroxide be used as a stand-alone energy source?

    International Nuclear Information System (INIS)

    Disselkamp, Robert S.

    2010-01-01

    A novel electrochemical scheme to convert a stand-alone supply of aqueous hydrogen peroxide into a fuel cell-ready stream of hydrogen gas plus aqueous hydrogen peroxide is described. The electrochemical cell, consisting of a solid base and solid acid electrocatalyst, together with a proton exchange membrane, comprise the system that converts aqueous hydrogen peroxide into separate gas streams of oxygen and hydrogen. Aqueous hydrogen peroxide is contained in the anode compartment only and exists in the region where oxygen gas is formed, whereas the cathode compartment is where hydrogen gas is generated and therefore exists in a reduced state. A near zero theoretical over-potential can be achieved by the choice of basicity and acidity of the electrode materials. The primary cost of the electrochemical cell is electrode construction and the aqueous hydrogen peroxide energy storage compound. Additional research effort is required to experimentally validate the concept and explore the full economic impact should initial studies, based on the design presented here, prove promising. (author)

  11. Battery Storage Technologies for Electrical Applications: Impact in Stand-Alone Photovoltaic Systems

    Directory of Open Access Journals (Sweden)

    Daniel Akinyele

    2017-11-01

    Full Text Available Batteries are promising storage technologies for stationary applications because of their maturity, and the ease with which they are designed and installed compared to other technologies. However, they pose threats to the environment and human health. Several studies have discussed the various battery technologies and applications, but evaluating the environmental impact of batteries in electrical systems remains a gap that requires concerted research efforts. This study first presents an overview of batteries and compares their technical properties such as the cycle life, power and energy densities, efficiencies and the costs. It proposes an optimal battery technology sizing and selection strategy, and then assesses the environmental impact of batteries in a typical renewable energy application by using a stand-alone photovoltaic (PV system as a case study. The greenhouse gas (GHG impact of the batteries is evaluated based on the life cycle emission rate parameter. Results reveal that the battery has a significant impact in the energy system, with a GHG impact of about 36–68% in a 1.5 kW PV system for different locations. The paper discusses new batteries, strategies to minimize battery impact and provides insights into the selection of batteries with improved cycling capacity, higher lifespan and lower cost that can achieve lower environmental impacts for future applications.

  12. Approaches for developing a sizing method for stand-alone PV systems with variable demand

    Energy Technology Data Exchange (ETDEWEB)

    Posadillo, R. [Grupo de Investigacion en Energias y Recursos Renovables, Dpto. de Fisica Aplicada, E.P.S., Universidad de Cordoba, Avda. Menendez Pidal s/n, 14004 Cordoba (Spain); Lopez Luque, R. [Grupo de Investigacion de Fisica para las Energias y Recursos Renovables, Dpto. de Fisica Aplicada. Edificio C2 Campus de Rabanales, 14071 Cordoba (Spain)

    2008-05-15

    Accurate sizing is one of the most important aspects to take into consideration when designing a stand-alone photovoltaic system (SAPV). Various methods, which differ in terms of their simplicity or reliability, have been developed for this purpose. Analytical methods, which seek functional relationships between variables of interest to the sizing problem, are one of these approaches. A series of rational considerations are presented in this paper with the aim of shedding light upon the basic principles and results of various sizing methods proposed by different authors. These considerations set the basis for a new analytical method that has been designed for systems with variable monthly energy demands. Following previous approaches, the method proposed is based on the concept of loss of load probability (LLP) - a parameter that is used to characterize system design. The method includes information on the standard deviation of loss of load probability ({sigma}{sub LLP}) and on two new parameters: annual number of system failures (f) and standard deviation of annual number of failures ({sigma}{sub f}). The method proves useful for sizing a PV system in a reliable manner and serves to explain the discrepancies found in the research on systems with LLP<10{sup -2}. We demonstrate that reliability depends not only on the sizing variables and on the distribution function of solar radiation, but on the minimum value as well, which in a given location and with a monthly average clearness index, achieves total solar radiation on the receiver surface. (author)

  13. The Method of a Standalone Functional Verifying Operability of Sonar Control Systems

    Directory of Open Access Journals (Sweden)

    A. A. Sotnikov

    2014-01-01

    Full Text Available This article describes a method of standalone verifying sonar control system, which is based on functional checking of control system operability.The main features of realized method are a development of the valid mathematic model for simulation of sonar signals at the point of hydroacoustic antenna, a valid representation of the sonar control system modes as a discrete Markov model, providing functional object verification in real time mode.Some ways are proposed to control computational complexity in case of insufficient computing resources of the simulation equipment, namely the way of model functionality reduction and the way of adequacy reduction.Experiments were made using testing equipment, which was developed by department of Research Institute of Information Control System at Bauman Moscow State Technical University to verify technical validity of industrial sonar complexes.On-board software was artificially changed to create malfunctions in functionality of sonar control systems during the verifying process in order to estimate verifying system performances.The method efficiency was proved by the theory and experiment results in comparison with the basic methodology of verifying technical systems.This method could be also used in debugging of on-board software of sonar complexes and in development of new promising algorithms of sonar signal processing.

  14. On the economics of stand-alone renewable hybrid power plants in remote regions

    International Nuclear Information System (INIS)

    Petrakopoulou, Fontina

    2016-01-01

    Highlights: • Economic evaluation of three renewable hybrid power plants for off-grid operation. • The high electricity cost of remote regions increases the competitiveness of renewable energy. • The proposed plants are economically viable when compared to the existing situation. • The zero direct emissions of the plants constitute an additional advantage of the plants. - Abstract: In recent years ever more examples of regions that have managed to achieve or orientate themselves toward renewable energy sufficiency are emerging. However, actions to create energy autonomy are mainly the result of isolated activities and they are less driven from fully organized movements. In addition, total energy independence without the support of a centralized electrical grid is yet to be achieved. The objectives of this work are to investigate the associated costs of stand-alone renewable hybrid power plants on a Greek island and compare them to the cost of the currently used fossil-fuel-based conventional plant. The plants examined here are designed to fully cover the electricity needs of the island. Islands may face numerous energy problems and rely heavily on foreign and environmentally-harmful fuels. It is shown that the relatively high cost of electricity of such a remote region can increase the competitiveness and promote the wider incorporation of technologies based on renewable energy sources that may, in other cases, seem economically inferior to business-as-usual energy solutions.

  15. Use of Super-Capacitor to Enhance Charging Performance of Stand-Alone Solar PV System

    KAUST Repository

    Huang, B. J.

    2011-01-01

    Introduction: The battery charging performance in a stand-alone solar PV system affects the PV system efficiency and the load operating time. The New Energy Center of National Taiwan University has been devoted to the development of a PWM charging technique to continue charging the lead-acid battery after the overcharge point to increase the battery storage capacity by more than 10%. The present study intends to use the super-capacitor to further increase the charge capacity before the overcharge point of the battery. The super-capacitor is connected in parallel to the lead-acid battery. This will reduce the overall charging impedance during the charge and increase the charging current, especially in sunny weather. A system dynamics model of the lead-acid battery and super-capacitor was derived and the control system simulation was carried out to predict the charging performance for various weathers. It shows that the overall battery impedance decreases and charging power increases with increasing solar radiation. An outdoor comparative test for two identical PV systems with and without supercapacitor was carried out. The use of super-capacitor is shown to be able to increase the lead-acid charging capacity by more than 25% at sunny weather and 10% in cloudy weather. © Springer-Verlag Berlin Heidelberg 2011.

  16. Graphene-Based Standalone Solar Energy Converter for Water Desalination and Purification.

    Science.gov (United States)

    Yang, Yang; Zhao, Ruiqi; Zhang, Tengfei; Zhao, Kai; Xiao, Peishuang; Ma, Yanfeng; Ajayan, Pulickel M; Shi, Gaoquan; Chen, Yongsheng

    2018-01-23

    Harvesting solar energy for desalination and sewage treatment has been considered as a promising solution to produce clean water. However, state-of-the-art technologies often require optical concentrators and complicated systems with multiple components, leading to poor efficiency and high cost. Here, we demonstrate an extremely simple and standalone solar energy converter consisting of only an as-prepared 3D cross-linked honeycomb graphene foam material without any other supporting components. This simple all-in-one material can act as an ideal solar thermal converter capable of capturing and converting sunlight into heat, which in turn can distill water from various water sources into steam and produce purified water under ambient conditions and low solar flux with very high efficiency. High specific water production rate of 2.6 kg h -1 m -2 g -1 was achieved with near ∼87% under 1 sun intensity and >80% efficiency even under ambient sunlight (solar thermal water purification system for a variety of environmental conditions.

  17. prfectBLAST: a platform-independent portable front end for the command terminal BLAST+ stand-alone suite.

    Science.gov (United States)

    Santiago-Sotelo, Perfecto; Ramirez-Prado, Jorge Humberto

    2012-11-01

    prfectBLAST is a multiplatform graphical user interface (GUI) for the stand-alone BLAST+ suite of applications. It allows researchers to do nucleotide or amino acid sequence similarity searches against public (or user-customized) databases that are locally stored. It does not require any dependencies or installation and can be used from a portable flash drive. prfectBLAST is implemented in Java version 6 (SUN) and runs on all platforms that support Java and for which National Center for Biotechnology Information has made available stand-alone BLAST executables, including MS Windows, Mac OS X, and Linux. It is free and open source software, made available under the GNU General Public License version 3 (GPLv3) and can be downloaded at www.cicy.mx/sitios/jramirez or http://code.google.com/p/prfectblast/.

  18. Design and standalone characterisation of a capacitively coupled HV-CMOS sensor chip for the CLIC vertex detector

    Science.gov (United States)

    Kremastiotis, I.; Ballabriga, R.; Campbell, M.; Dannheim, D.; Fiergolski, A.; Hynds, D.; Kulis, S.; Peric, I.

    2017-09-01

    The concept of capacitive coupling between sensors and readout chips is under study for the vertex detector at the proposed high-energy CLIC electron positron collider. The CLICpix Capacitively Coupled Pixel Detector (C3PD) is an active High-Voltage CMOS sensor, designed to be capacitively coupled to the CLICpix2 readout chip. The chip is implemented in a commercial 180 nm HV-CMOS process and contains a matrix of 128×128 square pixels with 25μm pitch. First prototypes have been produced with a standard resistivity of ~20 Ωcm for the substrate and tested in standalone mode. The results show a rise time of ~20 ns, charge gain of 190 mV/ke- and ~40 e- RMS noise for a power consumption of 4.8μW/pixel. The main design aspects, as well as standalone measurement results, are presented.

  19. Flexible Control of Small Wind Turbines With Grid Failure Detection Operating in Stand-Alone and Grid-Connected Mode

    DEFF Research Database (Denmark)

    Teodorescu, Remus; Blaabjerg, Frede

    2004-01-01

    This paper presents the development and test of a flexible control strategy for an 11-kw wind turbine with a back-to-back power converter capable of working in both stand-alone and grid-connected mode. The stand-alone control is featured with a complex output voltage controller capable of handling...... nonlinear load and excess or deficit of generated power. Grid-connection mode with current control is also enabled for the case of isolated local grid involving other dispersed power generators such as other wind turbines or diesel generators. A novel automatic mode switch method based on a phase......-locked loop controller is developed in order to detect the grid failure or recovery and switch the operation mode accordingly. A flexible digital signal processor (DSP) system that allows user-friendly code development and on-line tuning is used to implement and test the different control strategies. The back...

  20. Neural Network based Control of SG based Standalone Generating System with Energy Storage for Power Quality Enhancement

    Science.gov (United States)

    Nayar, Priya; Singh, Bhim; Mishra, Sukumar

    2017-08-01

    An artificial intelligence based control algorithm is used in solving power quality problems of a diesel engine driven synchronous generator with automatic voltage regulator and governor based standalone system. A voltage source converter integrated with a battery energy storage system is employed to mitigate the power quality problems. An adaptive neural network based signed regressor control algorithm is used for the estimation of the fundamental component of load currents for control of a standalone system with load leveling as an integral feature. The developed model of the system performs accurately under varying load conditions and provides good dynamic response to the step changes in loads. The real time performance is achieved using MATLAB along with simulink/simpower system toolboxes and results adhere to an IEEE-519 standard for power quality enhancement.

  1. Screening for drug and alcohol abuse among older adults using a modified version of the CAGE.

    Science.gov (United States)

    Hinkin, C H; Castellon, S A; Dickson-Fuhrman, E; Daum, G; Jaffe, J; Jarvik, L

    2001-01-01

    This study examined the sensitivity, specificity, and receiver operating characteristics (ROC) curves of a modified version of the CAGE, a screening measure used in the detection of older alcohol- and drug-abusing individuals. In a retrospective review of clinical records of 976 patients screened by a geriatric substance abuse program, the authors examined patients' responses on a modified version of the CAGE that included queries regarding drug use. The CAGE was administered to individuals age 50 or over draw from three diagnostic groups: alcohol abuse/dependence, drug abuse/dependence, and normal controls. Analysis of variance and discriminant function analyses revealed that the modified CAGE was able to discriminate both alcohol and drug abusers from controls. Analyses examining test sensitivity, specificity, and ROC curves revealed the CAGE to demonstrate excellent sensitivity but poor specificity. Omitting the "cut down'' item from the CAGE significantly improved specificity with only a modest drop in sensitivity. Given the ease of administration and sensitivity to both alcohol and drug abuse, these data suggest that the modified CAGE is well suited as a screening instrument for geriatric drug and alcohol abuse.

  2. Effect of curcumin caged silver nanoparticle on collagen stabilization for biomedical applications.

    Science.gov (United States)

    Srivatsan, Kunnavakkam Vinjimur; Duraipandy, N; Begum, Shajitha; Lakra, Rachita; Ramamurthy, Usha; Korrapati, Purna Sai; Kiran, Manikantan Syamala

    2015-04-01

    The current study aims at understanding the influence of curcumin caged silver nanoparticle (CCSNP) on stability of collagen. The results indicated that curcumin caged silver nanoparticles efficiently stabilize collagen, indicated by enhanced tensile strength, fibril formation and viscosity. The tensile strength of curcumin caged silver nanoparticle cross-linked collagen and elongation at break was also found to be higher than glutaraldehyde cross-linked collagen. The physicochemical characteristics of curcumin caged nanoparticle cross-linked collagen exhibited enhanced strength. The thermal properties were also good with both thermal degradation temperature and hydrothermal stability higher than native collagen. CD analysis showed no structural disparity in spite of superior physicochemical properties suggesting the significance of curcumin caged nanoparticle mediated cross-linking. The additional enhancement in the stabilization of collagen could be attributed to multiple sites for interaction with collagen molecule provided by curcumin caged silver nanoparticles. The results of cell proliferation and anti-microbial activity assays indicated that curcumin caged silver nanoparticles promoted cell proliferation and inhibited microbial growth making it an excellent biomaterial for wound dressing application. The study opens scope for nano-biotechnological strategies for the development of alternate non-toxic cross-linking agents facilitating multiple site interaction thereby improving therapeutic values to the collagen for biomedical application. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Digestibility and behavior of dogs housed in kennels or metabolic cages

    Directory of Open Access Journals (Sweden)

    Tabyta Tamara Sabchuk

    2012-01-01

    Full Text Available The objective of the present study was to compare the apparent digestibility coefficients of a commercial dog food, fecal consistency and behavior of dogs housed in kennels and metabolic cages. Six adult Beagle dogs were distributed in cross-over experimental design, with six replicates per treatment. Dogs were housed in two environments: metabolic cages and in masonry kennels with solarium. Dogs were fed for a five-day adaptation period, and the five following days were used for total feces collection. Dogs behavior was recorded during a 48-h period, with 10-min intervals. Apparent digestibility coefficients were not different between treatments. However, dogs housed in metabolic cages produced lower weight and more consistent feces as compared with dogs housed in kennels. Dogs spent most of the time sleeping in both housing systems; however, dogs housed in the metabolic cages slept more than those in kennels. Stress-related behaviors (barking, whimpering, stereotypies, etc were observed for no longer than 15 minutes per day, and were not different between dogs in kennels or in cages. There is no difference in food digestibility evaluated in dogs housed in metabolic cages or kennels; however, dogs kept in metabolic cages eliminate drier feces and spend more time inactive than those kept in kennels.

  4. Efficient energy control strategies for a Standalone Renewable/Fuel Cell Hybrid Power Source

    International Nuclear Information System (INIS)

    Bizon, Nicu; Oproescu, Mihai; Raceanu, Mircea

    2015-01-01

    Highlights: • A load – following control that operates the battery in charge – sustained mode. • A real-time Maximum Efficiency Point Tracking control that saves hydrogen fuel. • A comparative study of four strategies to control the fueling rates of the fuel cell stack. • Four control strategy for the HPS under unknown RES and load power profile are analyzed. • An increase of 3–5% of fuel efficiency was observed for the best strategy proposed. - Abstract: In this paper, four energy control strategies are proposed and analyzed for the standalone Renewable/Fuel Cell Hybrid Power Source (RES/FC HPS). The concept of the load following (LF) and Maximum Efficiency Point Tracking (MEPT) is used to control the fueling rates. A standalone RES/FC HPS uses at least one Renewable Energy Sources (RES) and a Polymer Electrolyte Membrane (PEM) Fuel Cell (FC) as backup source. Photovoltaic (PV) array and wind turbines (WT) farm are used as RES and the surplus of energy during light load stages is stored in hydrogen tank via water electrolysis to fuel the PEMFC. Small-scale RESs and commercially available PEMFCs are interfaced to the common DC bus via power converters and then to the single-phase distribution grid through a voltage source inverter. RES/FC HPS seem to be an efficient alternative for supplying smart houses and isolated sites. This paper proposes a new supervision strategy of the Energy Management Unit (EMU) based on the LF control approach that assures a charge-sustaining (CS) mode for the Energy Storage System (ESS). So, the capacity of the batteries stack can be reduced at minimum if it is directly connected to the DC bus. The ultracapacitors stack compensates dynamically the power flow balance on the DC bus, regulating the DC voltage via a bidirectional buck-boost power converter. Thus, a semi-active hybrid topology is adopted for the ESS having the batteries stack. The MEPT loops ensure an optimized energy management of the RES/FC HPS. The LF

  5. Assistive Technology

    Science.gov (United States)

    ... Page Resize Text Printer Friendly Online Chat Assistive Technology Assistive technology (AT) is any service or tool that helps ... be difficult or impossible. For older adults, such technology may be a walker to improve mobility or ...

  6. Assisted Living

    Science.gov (United States)

    Assisted living is for adults who need help with everyday tasks. They may need help with dressing, bathing, ... don't need full-time nursing care. Some assisted living facilities are part of retirement communities. Others are ...

  7. X-ray microbeam stand-alone facility for cultured cells irradiation

    International Nuclear Information System (INIS)

    Bożek, Sebastian; Bielecki, Jakub; Wiecheć, Anna; Lekki, Janusz; Stachura, Zbigniew; Pogoda, Katarzyna; Lipiec, Ewelina; Tkocz, Konrad; Kwiatek, Wojciech M.

    2017-01-01

    Highlights: • An X-ray microbeam line for irradiation of living cultured cells was constructed. • A step by step explanation of working principles with engineering details, procedures and calculations is presented. • A model of beam and cell interaction is presented. • A method of uniform irradiation of living cells with an exact dose per a cell is presented. • Results of preliminary experiments are presented. - Abstract: The article describes an X-ray microbeam standalone facility dedicated for irradiation of living cultured cells. The article can serve as an advice for such facilities construction, as it begins from engineering details, through mathematical modeling and experimental procedures, ending up with preliminary experimental results and conclusions. The presented system consists of an open type X-ray tube with microfocusing down to about 2 μm, an X-ray focusing system with optical elements arranged in the nested Kirckpatrick-Baez (or Montel) geometry, a sample stand and an optical microscope with a scientific digital CCD camera. For the beam visualisation an X-ray sensitive CCD camera and a spectral detector are used, as well as a scintillator screen combined with the microscope. A method of precise one by one irradiation of previously chosen cells is presented, as well as a fast method of uniform irradiation of a chosen sample area. Mathematical models of beam and cell with calculations of kerma and dose are presented. The experiments on dose-effect relationship, kinetics of DNA double strand breaks repair, as well as micronuclei observation were performed on PC-3 (Prostate Cancer) cultured cells. The cells were seeded and irradiated on Mylar foil, which covered a hole drilled in the Petri dish. DNA lesions were visualised with γ-H2AX marker combined with Alexa Fluor 488 fluorescent dye.

  8. Retrospective analysis of billing at a standalone medication therapy management clinic.

    Science.gov (United States)

    Hager, Keri D; Gosser, Rena A

    2016-01-15

    Results of a study comparing reimbursement for medication therapy management (MTM) services with a resource-based relative value scale (RBRVS) versus a time-based billing model are reported. Reimbursement claims for MTM services provided by a standalone clinic during a 6.5-year period were reviewed. Actual billing amounts calculated according to Minnesota's RBRVS for MTM services, which emphasizes case complexity as a determinant of payment rates, were compared with hypothetical billing amounts calculated using a strictly time-based method designed to more accurately capture the costs of providing MTM services. A paired t test was conducted to analyze differences in the billable amounts calculated via the two methods. Reimbursement claims for a total of 525 face-to-face MTM encounters with 60 patients were analyzed. Using the RBRVS method, the mean ± S.D. billing amount per encounter was $83.71 ± $36.67; using the strictly time-based method, the mean ± S.D. billing amount was $111.83 ± $34.55 per encounter (mean difference, $28.12; p billing methodology would have resulted in an additional $14,763 in MTM services reimbursement for the 525 evaluated encounters. The RBRVS-based method consistently resulted in a lower billing amount per encounter than the strictly time-based billing method, suggesting that reimbursement for MTM services may not be aligned with the actual costs of providing those services. Copyright © 2016 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  9. The eBioKit, a stand-alone educational platform for bioinformatics.

    Science.gov (United States)

    Hernández-de-Diego, Rafael; de Villiers, Etienne P; Klingström, Tomas; Gourlé, Hadrien; Conesa, Ana; Bongcam-Rudloff, Erik

    2017-09-01

    Bioinformatics skills have become essential for many research areas; however, the availability of qualified researchers is usually lower than the demand and training to increase the number of able bioinformaticians is an important task for the bioinformatics community. When conducting training or hands-on tutorials, the lack of control over the analysis tools and repositories often results in undesirable situations during training, as unavailable online tools or version conflicts may delay, complicate, or even prevent the successful completion of a training event. The eBioKit is a stand-alone educational platform that hosts numerous tools and databases for bioinformatics research and allows training to take place in a controlled environment. A key advantage of the eBioKit over other existing teaching solutions is that all the required software and databases are locally installed on the system, significantly reducing the dependence on the internet. Furthermore, the architecture of the eBioKit has demonstrated itself to be an excellent balance between portability and performance, not only making the eBioKit an exceptional educational tool but also providing small research groups with a platform to incorporate bioinformatics analysis in their research. As a result, the eBioKit has formed an integral part of training and research performed by a wide variety of universities and organizations such as the Pan African Bioinformatics Network (H3ABioNet) as part of the initiative Human Heredity and Health in Africa (H3Africa), the Southern Africa Network for Biosciences (SAnBio) initiative, the Biosciences eastern and central Africa (BecA) hub, and the International Glossina Genome Initiative.

  10. Stand-alone rolling circle amplification combined with capillary electrophoresis for specific detection of small RNA.

    Science.gov (United States)

    Li, Ni; Jablonowski, Carolyn; Jin, Hailing; Zhong, Wenwan

    2009-06-15

    Noncoding small RNAs play diverse, important biological roles through gene expression regulation. However, their low expression levels make it difficult to identify new small RNA species and study their functions, calling for the development of detection schemes with higher simplicity, sensitivity, and specificity. Herein, we reported a straightforward assay that combined the stand-alone rolling circle amplification (RCA) with capillary electrophoresis (CE) for specific and sensitive detection of small RNAs in biological samples. In order to enhance the overall reaction efficiency and simplify the procedure, RCA was not preceded with ligation, and a preformed circular probe was employed as the template for the target small RNA-primed isothermal amplification. The long RCA product was digested and analyzed by CE. Two DNA polymerases, the Phi29 and Bst, were compared for their detection performance. Bst is superior in the aspects of specificity, procedure simplicity, and reproducibility, while Phi29 leads to a 5-fold lower detection limit and is able to detect as low as 35 amol of the target small RNA. Coamplification of an internal standard with the target and employment of the RNase A digestion step allow accurate and reproducible quantification of low amounts of small RNA targets spiked into hundreds of nanograms of the plant total RNA extract with a recovery below 110% using either enzyme. Our assay can be adapted to a capillary array system for high-throughput screening of small RNA expression in biological samples. Also, the one-step isothermal process has the potential to conveniently amplify a very limited amount of the RNA samples, e.g., RNA extracted from only a few cells, inside the capillary column or on a microchip.

  11. "Candidatus Fokinia solitaria", a Novel "Stand-Alone" Symbiotic Lineage of Midichloriaceae (Rickettsiales.

    Directory of Open Access Journals (Sweden)

    Franziska Szokoli

    Full Text Available Recently, the family Midichloriaceae has been described within the bacterial order Rickettsiales. It includes a variety of bacterial endosymbionts detected in different metazoan host species belonging to Placozoa, Cnidaria, Arthropoda and Vertebrata. Representatives of Midichloriaceae are also considered possible etiological agents of certain animal diseases. Midichloriaceae have been found also in protists like ciliates and amoebae. The present work describes a new bacterial endosymbiont, "Candidatus Fokinia solitaria", retrieved from three different strains of a novel Paramecium species isolated from a wastewater treatment plant in Rio de Janeiro (Brazil. Symbionts were characterized through the full-cycle rRNA approach: SSU rRNA gene sequencing and fluorescence in situ hybridization (FISH with three species-specific oligonucleotide probes. In electron micrographs, the tiny rod-shaped endosymbionts (1.2 x 0.25-0.35 μm in size were not surrounded by a symbiontophorous vacuole and were located in the peripheral host cytoplasm, stratified in the host cortex in between the trichocysts or just below them. Frequently, they occurred inside autolysosomes. Phylogenetic analyses of Midichloriaceae apparently show different evolutionary pathways within the family. Some genera, such as "Ca. Midichloria" and "Ca. Lariskella", have been retrieved frequently and independently in different hosts and environmental surveys. On the contrary, others, such as Lyticum, "Ca. Anadelfobacter", "Ca. Defluviella" and the presently described "Ca. Fokinia solitaria", have been found only occasionally and associated to specific host species. These last are the only representatives in their own branches thus far. Present data do not allow to infer whether these genera, which we named "stand-alone lineages", are an indication of poorly sampled organisms, thus underrepresented in GenBank, or represent fast evolving, highly adapted evolutionary lineages.

  12. Optimum capacity determination of stand-alone hybrid generation system considering cost and reliability

    International Nuclear Information System (INIS)

    Chen, Hung-Cheng

    2013-01-01

    Highlights: ► This paper presents a methodology for the installation capacity optimization. ► Hybrid generation system is optimized by application of adaptive genetic algorithm. ► A cost investigation is made under various conditions and component characteristics. ► The optimization scheme is validated to meet the annual power load demand. -- Abstract: The aim of this work is to present an optimization methodology for the installation capacity of a stand-alone hybrid generation system, taking into consideration the cost and reliability. Firstly, on the basis of derived steady state models of a wind generator (WG), a photovoltaic array (PV), a battery and an inverter, the hybrid generation system is modeled for the purpose of capacity optimization. Secondly, the power system is analyzed for determining both the system structure and the operation control strategy. Thirdly, according to hourly weather database of wind speed, temperature and solar irradiation, annual power generation capacity is estimated for the system match design in order that an annual power load demand can be met. The capacity determination of a hybrid generation system becomes complicated as a result of the uncertainty in the renewable energy together with load demand and the nonlinearity of system components. Aimed at the power system reliability and the cost minimization, the capacity of a hybrid generation system is optimized by application of an adaptive genetic algorithm (AGA) to individual power generation units. A total cost investigation is made under various conditions, such as wind generator power curves, battery discharge depth and the loss of load probability (LOLP). At the end of this work, the capacity of a hybrid generation system is optimized at two installation sites, namely the offshore Orchid Island and Wuchi in Taiwan. The optimization scheme is validated to optimize power capacities of a photovoltaic array, a battery and a wind turbine generator with a relative

  13. A Low-Power Wearable Stand-Alone Tongue Drive System for People With Severe Disabilities.

    Science.gov (United States)

    Jafari, Ali; Buswell, Nathanael; Ghovanloo, Maysam; Mohsenin, Tinoosh

    2018-02-01

    This paper presents a low-power stand-alone tongue drive system (sTDS) used for individuals with severe disabilities to potentially control their environment such as computer, smartphone, and wheelchair using their voluntary tongue movements. A low-power local processor is proposed, which can perform signal processing to convert raw magnetic sensor signals to user-defined commands, on the sTDS wearable headset, rather than sending all raw data out to a PC or smartphone. The proposed sTDS significantly reduces the transmitter power consumption and subsequently increases the battery life. Assuming the sTDS user issues one command every 20 ms, the proposed local processor reduces the data volume that needs to be wirelessly transmitted by a factor of 64, from 9.6 to 0.15 kb/s. The proposed processor consists of three main blocks: serial peripheral interface bus for receiving raw data from magnetic sensors, external magnetic interference attenuation to attenuate external magnetic field from the raw magnetic signal, and a machine learning classifier for command detection. A proof-of-concept prototype sTDS has been implemented with a low-power IGLOO-nano field programmable gate array (FPGA), bluetooth low energy, battery and magnetic sensors on a headset, and tested. At clock frequency of 20 MHz, the processor takes 6.6 s and consumes 27 nJ for detecting a command with a detection accuracy of 96.9%. To further reduce power consumption, an application-specified integrated circuit processor for the sTDS is implemented at the postlayout level in 65-nm CMOS technology with 1-V power supply, and it consumes 0.43 mW, which is 10 lower than FPGA power consumption and occupies an area of only 0.016 mm.

  14. Imagery rescripting as a stand-alone treatment for patients with social phobia: a case series.

    Science.gov (United States)

    Frets, Petra G; Kevenaar, Ciska; van der Heiden, Colin

    2014-03-01

    The majority of patients with social phobia reports experiencing negative images, usually linked to memories of earlier aversive social experiences. Several studies have indicated that such negative self-imagery appears to have a causal role in maintaining social phobia, which suggests that interventions aimed at dealing with these images could be beneficial in the treatment of social phobia. One potentially powerful approach is imagery rescripting (IR), a clinical intervention that focuses on changing the meaning and impact of unpleasant memories. In the treatment of social phobia IR was only used as part of a broader cognitive-behavioral treatment package. However, we propose that IR alone might also be an effective treatment for this anxiety disorder. The present study reports an initial evaluation of the application of IR as a stand-alone treatment for six adult outpatients presenting with social phobia. A single case series using an A-B replication across patients design was employed. Following a no-treatment baseline period, IR was delivered weekly and patients were followed up for 3 and 6 months. For all patients, substantial reductions were obtained on all outcome measures at post-treatment, and gains were largely maintained at 6-months follow-up. The generalizability of the effects of IR for social phobia is limited by the small number of patients treated by only one therapist. The results of this preliminary case series suggest that IR as a stand alone treatment is an apparently effective intervention in the treatment of patients with social phobia, and indicate that controlled evaluation of its efficacy might be worthwhile. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. A standalone Internet cognitive behavior therapy treatment for social anxiety in adults who stutter: CBTpsych.

    Science.gov (United States)

    Helgadóttir, Fjóla Dögg; Menzies, Ross G; Onslow, Mark; Packman, Ann; O'Brian, Sue

    2014-09-01

    Social anxiety is common for those who stutter and efficacious cognitive behavior therapy (CBT) for them appears viable. However, there are difficulties with provision of CBT services for anxiety among those who stutter. Standalone Internet CBT treatment is a potential solution to those problems. CBTpsych is a fully automated, online social anxiety intervention for those who stutter. This report is a Phase I trial of CBTpsych. Fourteen participants were allowed 5 months to complete seven sections of CBTpsych. Pre-treatment and post-treatment assessments tested for social anxiety, common unhelpful thoughts related to stuttering, quality of life and stuttering frequency. Significant post-treatment improvements in social anxiety, unhelpful thoughts, and quality of life were reported. Five of seven participants diagnosed with social anxiety lost those diagnoses at post-treatment. The two participants who did not lose social anxiety diagnoses did not complete all the CBTpsych modules. CBTpsych did not improve stuttering frequency. Eleven of the fourteen participants who began treatment completed Section 4 or more of the CBTpsych intervention. CBTpsych provides a potential means to provide CBT treatment for social anxiety associated with stuttering, to any client without cost, regardless of location. Further clinical trials are warranted. At the end of this activity the reader will be able to: (a) describe that social anxiety is common in those who stutter; (b) discuss the origin of social anxiety and the associated link with bullying; (c) summarize the problems in provision of effective evidence based cognitive behavior therapy for adults who stutter; (d) describe a scalable computerized treatment designed to tackle the service provision gap; (e) describe the unhelpful thoughts associated with stuttering that this fully automated computer program was able to tackle; (f) list the positive outcomes for individuals who stuttered that participated in this trial such as the

  16. Stand-Alone Photovoltaic System Assessment in Warmer Urban Areas in Mexico

    Directory of Open Access Journals (Sweden)

    Alberto-Jesus Perea-Moreno

    2018-01-01

    Full Text Available The aim of this study is to examine the possibility of using a stand-alone photovoltaic system (SAPVS for electricity generation in urban areas in Southern Mexico. In Mexico, an urban area is defined as an area where more than 2500 inhabitants live. Due to constant migration from the countryside to the cities, the number of inhabitants of urban localities has been increasing. Global horizontal irradiation (GHI data were recorded every 10 min during 2014–2016 in Coatzacoalcos in the state of Veracruz located on 18°08′09″ N and 94°27′48″ W. In this study, batteries represented 77% of the total cost, 12 PV panels of 310 W could export 5.41 MWh to the grid, and an inverter with an integrated controller and charger was selected, which decreased the initial cost. The city of Coatzacoalcos was chosen because the average annual temperature is 28°, with an average relative humidity of 75% and an average irradiance of 5.3 kWh/m2/day. An emission factor 0.505 tCO2/MWh of greenhouse gases (GHG were obtained, based on the power system, the reduction of net annual GHG would be 11 tCO2 and a financial revenue of 36.951 × 103 $/tCO2 would be obtained. Financial parameters such as a 36.3% Internal Rate Return (IRR and 3.4 years payback show the financial viability of this investment. SAPVSs in urban areas in Mexico could be a benefit as long as housing has a high consumption of electricity.

  17. X-ray microbeam stand-alone facility for cultured cells irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Bożek, Sebastian, E-mail: sebastian.bozek@yahoo.com [Jagiellonian University Medical College, Department of Pharmaceutical Biophysics, Krakow (Poland); Bielecki, Jakub; Wiecheć, Anna; Lekki, Janusz; Stachura, Zbigniew; Pogoda, Katarzyna; Lipiec, Ewelina; Tkocz, Konrad; Kwiatek, Wojciech M. [Institute of Nuclear Physics Polish Academy of Sciences, PL-31342 Krakow (Poland)

    2017-03-01

    Highlights: • An X-ray microbeam line for irradiation of living cultured cells was constructed. • A step by step explanation of working principles with engineering details, procedures and calculations is presented. • A model of beam and cell interaction is presented. • A method of uniform irradiation of living cells with an exact dose per a cell is presented. • Results of preliminary experiments are presented. - Abstract: The article describes an X-ray microbeam standalone facility dedicated for irradiation of living cultured cells. The article can serve as an advice for such facilities construction, as it begins from engineering details, through mathematical modeling and experimental procedures, ending up with preliminary experimental results and conclusions. The presented system consists of an open type X-ray tube with microfocusing down to about 2 μm, an X-ray focusing system with optical elements arranged in the nested Kirckpatrick-Baez (or Montel) geometry, a sample stand and an optical microscope with a scientific digital CCD camera. For the beam visualisation an X-ray sensitive CCD camera and a spectral detector are used, as well as a scintillator screen combined with the microscope. A method of precise one by one irradiation of previously chosen cells is presented, as well as a fast method of uniform irradiation of a chosen sample area. Mathematical models of beam and cell with calculations of kerma and dose are presented. The experiments on dose-effect relationship, kinetics of DNA double strand breaks repair, as well as micronuclei observation were performed on PC-3 (Prostate Cancer) cultured cells. The cells were seeded and irradiated on Mylar foil, which covered a hole drilled in the Petri dish. DNA lesions were visualised with γ-H2AX marker combined with Alexa Fluor 488 fluorescent dye.

  18. Stand-Alone Solar Organic Rankine Cycle Water Pumping System and Its Economic Viability in Nepal

    Directory of Open Access Journals (Sweden)

    Suresh Baral

    2015-12-01

    Full Text Available The current study presents the concept of a stand-alone solar organic Rankine cycle (ORC water pumping system for rural Nepalese areas. Experimental results for this technology are presented based on a prototype. The economic viability of the system was assessed based on solar radiation data of different Nepalese geographic locations. The mechanical power produced by the solar ORC is coupled with a water pumping system for various applications, such as drinking and irrigation. The thermal efficiency of the system was found to be 8% with an operating temperature of 120 °C. The hot water produced by the unit has a temperature of 40 °C. Economic assessment was done for 1-kW and 5-kW solar ORC water pumping systems. These systems use different types of solar collectors: a parabolic trough collector (PTC and an evacuated tube collector (ETC. The economic analysis showed that the costs of water are $2.47/m3 (highest and $1.86/m3 (lowest for the 1-kW system and a 150-m pumping head. In addition, the cost of water is reduced when the size of the system is increased and the pumping head is reduced. The minimum volumes of water pumped are 2190 m3 and 11,100 m3 yearly for 1 kW and 5 kW, respectively. The payback period is eight years with a profitability index of 1.6. The system is highly feasible and promising in the context of Nepal.

  19. Feasibility study and energy conversion analysis of stand-alone hybrid renewable energy system

    International Nuclear Information System (INIS)

    Baghdadi, Fazia; Mohammedi, Kamal; Diaf, Said; Behar, Omar

    2015-01-01

    Highlights: • Hybrid stand-alone wind–solar–fossil power system is analyzed. • Measurement data are used to evaluate system performance. • The proposed system can generate about 70% from renewables. • Such a hybrid plant is very promising for remote regions in Algeria. - Abstract: There is a great interest in the development of renewable power technologies in Algeria, and more particularly hybrid concept. The present paper has investigated the performance of hybrid PV–Wind–Diesel–Battery configuration based on hourly measurements of Adrar climate (southern Algeria). Data of global solar radiation, ambient temperature and wind speed for a period of one year have been used. Firstly, the proposed hybrid system has been optimized by means of HOMER software. The optimization process has been carried out taking into account renewable resources potential and energy demand; while maximizing renewable electricity use and fuel saving are the purpose. In the second step, a mathematical model has been developed to ensure efficient energy management on the basis of various operation strategies. The analysis has shown that renewable energy system (PV–Wind) is able to supply about 70% of the demand. Wind power has ranked first with 43% of the annual total electricity production followed by diesel generator (with 31%) while the remaining fraction is being to PV panels. In this context, 69% of the fossil fuel can be saved when using the proposed hybrid configuration instead of the diesel generators that are currently installed in most remote regions in Algeria. Such a concept is very promising to meet the focus of renewable energy program announced in 2011.

  20. Probabilistic modelling and analysis of stand-alone hybrid power systems

    International Nuclear Information System (INIS)

    Lujano-Rojas, Juan M.; Dufo-López, Rodolfo; Bernal-Agustín, José L.

    2013-01-01

    As a part of the Hybrid Intelligent Algorithm, a model based on an ANN (artificial neural network) has been proposed in this paper to represent hybrid system behaviour considering the uncertainty related to wind speed and solar radiation, battery bank lifetime, and fuel prices. The Hybrid Intelligent Algorithm suggests a combination of probabilistic analysis based on a Monte Carlo simulation approach and artificial neural network training embedded in a genetic algorithm optimisation model. The installation of a typical hybrid system was analysed. Probabilistic analysis was used to generate an input–output dataset of 519 samples that was later used to train the ANNs to reduce the computational effort required. The generalisation ability of the ANNs was measured in terms of RMSE (Root Mean Square Error), MBE (Mean Bias Error), MAE (Mean Absolute Error), and R-squared estimators using another data group of 200 samples. The results obtained from the estimation of the expected energy not supplied, the probability of a determined reliability level, and the estimation of expected value of net present cost show that the presented model is able to represent the main characteristics of a typical hybrid power system under uncertain operating conditions. - Highlights: • This paper presents a probabilistic model for stand-alone hybrid power system. • The model considers the main sources of uncertainty related to renewable resources. • The Hybrid Intelligent Algorithm has been applied to represent hybrid system behaviour. • The installation of a typical hybrid system was analysed. • The results obtained from the study case validate the presented model

  1. Optimum autonomous stand-alone photovoltaic system design on the basis of energy pay-back analysis

    International Nuclear Information System (INIS)

    Kaldellis, J.K.; Zafirakis, D.; Kondili, E.

    2009-01-01

    Stand-alone photovoltaic (PV) systems comprise one of the most promising electrification solutions for covering the demand of remote consumers. However, such systems are strongly questioned due to extreme life-cycle (LC) energy requirements. For similar installations to be considered as environmentally sustainable, their LC energy content must be compensated by the respective useful energy production, i.e. their energy pay-back period (EPBP) should be found less than their service period. In this context, an optimum sizing methodology is currently developed, based on the criterion of minimum embodied energy. Various energy autonomous stand-alone PV-lead-acid battery systems are examined and two different cases are investigated; a high solar potential area and a medium solar potential area. By considering that the PV-battery (PV-Bat) system's useful energy production is equal to the remote consumer's electricity consumption, optimum cadmium telluride (CdTe) based systems yield the minimum EPBP (15 years). If achieving to exploit the net PV energy production however, the EPBP is found less than 20 years for all PV types. Finally, the most interesting finding concerns the fact that in all cases examined the contribution of the battery component exceeds 27% of the system LC energy requirements, reflecting the difference between grid-connected and stand-alone configurations.

  2. Control strategy of wind turbine based on permanent magnet synchronous generator and energy storage for stand-alone systems

    DEFF Research Database (Denmark)

    Deng, Fujin; Liu, Dong; Chen, Zhe

    2017-01-01

    This paper investigates a variable speed wind turbine based on permanent magnet synchronous generator and a full-scale power converter in a stand-alone system. An energy storage system(ESS) including battery and fuel cell-electrolyzer combination is connected to the DC link of the full-scale power...... converter through the power electronics interface. Wind is the primary power source of the system, the battery and FC-electrolyzer combination is used as a backup and a long-term storage system to provide or absorb power in the stand-alone system, respectively. In this paper, a control strategy is proposed...... for the operation of this variable speed wind turbine in a stand-alone system, where the generator-side converter and the ESS operate together to meet the demand of the loads. This control strategy is competent for supporting the variation of the loads or wind speed and limiting the DC-link voltage of the full...

  3. Evolution of lone pair of excess electrons inside molecular cages with the deformation of the cage in e2@C60F60 systems.

    Science.gov (United States)

    Wang, Yin-Feng; Chen, Wei; Yu, Guang-Tao; Li, Zhi-Ru; Wu, Di; Sun, Chia-Chung

    2011-07-15

    For unusual e(2)@C(60)F(60)(I(h), D(6h), and D(5d)) cage structures with two excess electrons, it is reported that not only the lone pair in singlet state but also two single excess electrons in triplet state can be encapsulated inside the C(60)F(60) cages to form single molecular solvated dielectrons. The interesting relationship between the shape of the cage and the spin state of the system has revealed that ground states are singlet state for spherical shaped e(2)@C(60)F(60)(I(h)) and triplet states for short capsular shaped e(2)@C(60)F(60)(D(6h)) and long capsular shaped e(2)@C(60)F(60)(D(5d)), which shows a spin evolution from the singlet to triplet state with the deformation of the cage from spherical to capsular shape. For these excess electron systems, the three ground state structures have large vertical electron detachment energies (VDEs (I) of 1.720-2.283 eV and VDEs (II) of 3.959-5.288 eV), which shows their stabilities and suggests that the large C(60)F(60) cage is the efficient container of excess electrons. Copyright © 2011 Wiley Periodicals, Inc.

  4. Chiral Organic Cages with a Triple-Stranded Helical Structure Derived from Helicene.

    Science.gov (United States)

    Malik, Abaid Ullah; Gan, Fuwei; Shen, Chengshuo; Yu, Na; Wang, Ruibin; Crassous, Jeanne; Shu, Mouhai; Qiu, Huibin

    2018-02-28

    We report the use of helicene with an intrinsic helical molecular structure to prepare covalent organic cages via imine condensation. The organic cages revealed a [3+2]-type architecture containing a triple-stranded helical structure with three helicene units arranged in a propeller-like fashion with the framework integrally twisted. Such structural chirality was retained upon dissolution in organic solvents, as indicated by a strong diastereotopy effect in proton NMR and unique Cotton effects in circular dichroism spectra. Further study on chiral adsorption showed that the chiral organic cages possess considerable enantioselectivity toward a series of aromatic racemates.

  5. A practical guide to the synthesis of dinitroindolinyl-caged neurotransmitters.

    Science.gov (United States)

    Ellis-Davies, Graham C R

    2011-03-01

    This protocol describes a method for efficient chemical synthesis of dinitroindolinyl derivatives of glutamate and γ-aminobutyric acid. These caged neurotransmitters are currently the most chemically and photochemically efficient probes for two-photon photolysis in living brain slices. The protocol only requires basic organic synthesis equipment, and no silica gel column chromatography or NMR spectroscopy is needed at any stage. HPLC is used to purify the caged transmitters at the end of the syntheses. Thus, the synthesis of dinitroindolinyl-caged neurotransmitters is within the scope of a modestly equipped chemistry laboratory.

  6. Spiro annulation of cage polycycles via Grignard reaction and ring-closing metathesis as key steps

    Directory of Open Access Journals (Sweden)

    Sambasivarao Kotha

    2015-08-01

    Full Text Available A simple synthetic strategy to C2-symmetric bis-spiro-pyrano cage compound 7 involving ring-closing metathesis is reported. The hexacyclic dione 10 was prepared from simple and readily available starting materials such as 1,4-naphthoquinone and cyclopentadiene. The synthesis of an unprecedented octacyclic cage compound through intramolecular Diels–Alder (DA reaction as a key step is described. The structures of three new cage compounds 7, 12 and 18 were confirmed by single crystal X-ray diffraction studies.

  7. Effects of declawing and cage shape on productivity, feathering, and fearfulness of egg-type chickens.

    Science.gov (United States)

    Vanskike, K P; Adams, A W

    1983-04-01

    Declawing day-old egg-type chicks did not significantly (P less than .05) alter 20-week body weight. However, declawed hens tended to mature earlier and lay more eggs than the intact hens. Hens housed in shallow cages tended to be better feathered than those housed in deep cages. Neither declawing nor cage shape had a significant effect on the time required for birds to return to feeding after exposure to a noise stimulus, which was used as an indicator of fearfulness.

  8. Investigation of different cage designs and mechano-regulation algorithms in the lumbar interbody fusion process - a finite element analysis.

    Science.gov (United States)

    Postigo, Sergio; Schmidt, Hendrik; Rohlmann, Antonius; Putzier, Michael; Simón, Antonio; Duda, Georg; Checa, Sara

    2014-04-11

    Lumbar interbody fusion cages are commonly used to treat painful spinal degeneration and instability by achieving bony fusion. Many different cage designs exist, however the effect of cage morphology and material properties on the fusion process remains largely unknown. This finite element model study aims to investigate the influence of different cage designs on bone fusion using two mechano-regulation algorithms of tissue formation. It could be observed that different cages play a distinct key role in the mechanical conditions within the fusion region and therefore regulate the time course of the fusion process. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. Assisted Living

    Science.gov (United States)

    ... it, too. Back to top What is the Cost for Assisted Living? Although assisted living costs less than nursing home ... Primarily, older persons or their families pay the cost of assisted living. Some health and long-term care insurance policies ...

  10. Accounts Assistant

    Indian Academy of Sciences (India)

    CHITRA

    (Not more than three months old). Annexure 1. Indian Academy of Sciences. C V Raman Avenue, Bengaluru 560 080. Application for the Post of: Accounts Assistant / Administrative Assistant Trainee / Assistant – Official Language. Implementation Policy / Temporary Copy Editor and Proof Reader / Social Media Manager. 1.

  11. Mating competitiveness of sterile male Anopheles coluzzii in large cages.

    Science.gov (United States)

    Maïga, Hamidou; Damiens, David; Niang, Abdoulaye; Sawadogo, Simon P; Fatherhaman, Omnia; Lees, Rosemary S; Roux, Olivier; Dabiré, Roch K; Ouédraogo, Georges A; Tripet, Fréderic; Diabaté, Abdoulaye; Gilles, Jeremie R L

    2014-11-26

    Understanding the factors that account for male mating competitiveness is critical to the development of the sterile insect technique (SIT). Here, the effects of partial sterilization with 90 Gy of radiation on sexual competitiveness of Anopheles coluzzii allowed to mate in different ratios of sterile to untreated males have been assessed. Moreover, competitiveness was compared between males allowed one versus two days of contact with females. Sterile and untreated males four to six days of age were released in large cages (~1.75 sq m) with females of similar age at the following ratios of sterile males: untreated males: untreated virgin females: 100:100:100, 300:100:100, 500:100:100 (three replicates of each) and left for two days. Competitiveness was determined by assessing the egg hatch rate and the insemination rate, determined by dissecting recaptured females. An additional experiment was conducted with a ratio of 500:100:100 and a mating period of either one or two days. Two controls of 0:100:100 (untreated control) and 100:0:100 (sterile control) were used in each experiment. When males and females consort for two days with different ratios, a significant difference in insemination rate was observed between ratio treatments. The competitiveness index (C) of sterile males compared to controls was 0.53. The number of days of exposure to mates significantly increased the insemination rate, as did the increased number of males present in the untreated: sterile male ratio treatments, but the number of days of exposure did not have any effect on the hatch rate. The comparability of the hatch rates between experiments suggest that An. coluzzii mating competitiveness experiments in large cages could be run for one instead of two days, shortening the required length of the experiment. Sterilized males were half as competitive as untreated males, but an effective release ratio of at least five sterile for one untreated male has the potential to impact the fertility of

  12. Methanol production via pressurized entrained flow biomass gasification – Techno-economic comparison of integrated vs. stand-alone production

    International Nuclear Information System (INIS)

    Andersson, Jim; Lundgren, Joakim; Marklund, Magnus

    2014-01-01

    The main objective with this work was to investigate techno-economically the opportunity for integrated gasification-based biomass-to-methanol production in an existing chemical pulp and paper mill. Three different system configurations using the pressurized entrained flow biomass gasification (PEBG) technology were studied, one stand-alone plant, one where the bark boiler in the mill was replaced by a PEBG unit and one with a co-integration of a black liquor gasifier operated in parallel with a PEBG unit. The cases were analysed in terms of overall energy efficiency (calculated as electricity-equivalents) and process economics. The economics was assessed under the current as well as possible future energy market conditions. An economic policy support was found to be necessary to make the methanol production competitive under all market scenarios. In a future energy market, integrating a PEBG unit to replace the bark boiler was the most beneficial case from an economic point of view. In this case the methanol production cost was reduced in the range of 11–18 Euro per MWh compared to the stand-alone case. The overall plant efficiency increased approximately 7%-units compared to the original operation of the mill and the non-integrated stand-alone case. In the case with co-integration of the two parallel gasifiers, an equal increase of the system efficiency was achieved, but the economic benefit was not as apparent. Under similar conditions as the current market and when methanol was sold to replace fossil gasoline, co-integration of the two parallel gasifiers was the best alternative based on received IRR. - Highlights: • Techno-economic results regarding integration of methanol synthesis processes in a pulp and paper mill are presented. • The overall energy efficiency increases in integrated methanol production systems compared to stand-alone production units. • The economics of the integrated system improves compared to stand-alone alternatives. • Tax

  13. Stand-Alone Personalized Normative Feedback for College Student Drinkers: A Meta-Analytic Review, 2004 to 2014.

    Directory of Open Access Journals (Sweden)

    Keri B Dotson

    Full Text Available Norms clarification has been identified as an effective component of college student drinking interventions, prompting research on norms clarification as a single-component intervention known as Personalized Normative Feedback (PNF. Previous reviews have examined PNF in combination with other components but not as a stand-alone intervention.To investigate the degree to which computer-delivered stand-alone personalized normative feedback interventions reduce alcohol consumption and alcohol-related harms among college students and to compare gender-neutral and gender-specific PNF.Electronic databases were searched systematically through November 2014. Reference lists were reviewed manually and forward and backward searches were conducted.Outcome studies that compared computer-delivered, stand-alone PNF intervention with an assessment only, attention-matched, or active treatment control and reported alcohol use and harms among college students.Between-group effect sizes were calculated as the standardized mean difference in change scores between treatment and control groups divided by pooled standard deviation. Within-group effect sizes were calculated as the raw mean difference between baseline and follow-up divided by pooled within-groups standard deviation.Eight studies (13 interventions with a total of 2,050 participants were included. Compared to control participants, students who received gender-neutral (dbetween = 0.291, 95% CI [0.159, 0.423] and gender-specific PNF (dbetween = 0.284, 95% CI [0.117, 0.451] reported greater reductions in drinking from baseline to follow-up. Students who received gender-neutral PNF reported 3.027 (95% CI [2.171, 3.882] fewer drinks per week at first follow-up and gender-specific PNF reported 3.089 (95% CI [0.992, 5.186] fewer drinks. Intervention effects were small for harms (dbetween = 0.157, 95% CI [0.037, 0.278].Computer-delivered PNF is an effective stand-alone approach for reducing college student

  14. Stand-Alone Personalized Normative Feedback for College Student Drinkers: A Meta-Analytic Review, 2004 to 2014.

    Science.gov (United States)

    Dotson, Keri B; Dunn, Michael E; Bowers, Clint A

    2015-01-01

    Norms clarification has been identified as an effective component of college student drinking interventions, prompting research on norms clarification as a single-component intervention known as Personalized Normative Feedback (PNF). Previous reviews have examined PNF in combination with other components but not as a stand-alone intervention. To investigate the degree to which computer-delivered stand-alone personalized normative feedback interventions reduce alcohol consumption and alcohol-related harms among college students and to compare gender-neutral and gender-specific PNF. Electronic databases were searched systematically through November 2014. Reference lists were reviewed manually and forward and backward searches were conducted. Outcome studies that compared computer-delivered, stand-alone PNF intervention with an assessment only, attention-matched, or active treatment control and reported alcohol use and harms among college students. Between-group effect sizes were calculated as the standardized mean difference in change scores between treatment and control groups divided by pooled standard deviation. Within-group effect sizes were calculated as the raw mean difference between baseline and follow-up divided by pooled within-groups standard deviation. Eight studies (13 interventions) with a total of 2,050 participants were included. Compared to control participants, students who received gender-neutral (dbetween = 0.291, 95% CI [0.159, 0.423]) and gender-specific PNF (dbetween = 0.284, 95% CI [0.117, 0.451]) reported greater reductions in drinking from baseline to follow-up. Students who received gender-neutral PNF reported 3.027 (95% CI [2.171, 3.882]) fewer drinks per week at first follow-up and gender-specific PNF reported 3.089 (95% CI [0.992, 5.186]) fewer drinks. Intervention effects were small for harms (dbetween = 0.157, 95% CI [0.037, 0.278]). Computer-delivered PNF is an effective stand-alone approach for reducing college student drinking and

  15. Effect of the environment inside and outside the cage on the activity and behaviour test performance of silver foxes

    Directory of Open Access Journals (Sweden)

    T. REKILÄ

    2008-12-01

    Full Text Available On the basis of daily activity in the home cage and the open field test the effect of the internal design and location of cages on the behaviour of silver foxes (Vulpes vulpes during a growth period was evaluated. The inclusion of platforms in cages increased the daytime activity of silver foxes in their home cage, but the inclusion of nest boxes did not. Silver foxes housed at the front of the animal barn were less active during the working day and more active in the evening than were animals housed at the rear. The results of the open field test did not differ significantly between animals housed in cages differing in design. This study demonstrates that the behaviour of silver foxes was only minimally affected by the interior environment of the cage, and that attempts to improve housing design should also take the environment outside the cage into account.;

  16. Squeezing clathrate cages to host trivalent rare-earth guests

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jian [Iowa State Univ., Ames, IA (United States). Department of Chemistry; Ames Lab., Ames, IA (United States); He, Yuping [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Mordvinova, Natalia E. [Laboratoire CRISMAT, ENSICAEN, CNRS UMR (France); Lebedev, Oleg [Laboratoire CRISMAT, ENSICAEN, CNRS UMR (France); Kovnir, Kirill [Iowa State Univ., Ames, IA (United States). Department of Chemistry; Ames Lab., Ames, IA (United States)

    2017-11-01

    Strike difference of the trivalent rare-earth cations from their alkali and alkaline-earth peers is in the presence of localized 4f-electrons and strong spin-orbit coupling. Placing trivalent rare-earth cations inside the fullerene molecules or in between the blocks of itinerant magnetic intermetallics gave rise to plethora of fascinating properties and materials. A long-time missing but hardly desired piece is the semiconducting or metallic compound where rare-earth cations are situated inside the oversized polyhedral cages of three-dimensional framework. In this work we present a synthesis of such compounds, rare-earth containing clathrates Ba8-xRxCu16P30. The unambiguous proofs of their composition and crystal structure were achieved by a combination of synchrotron powder diffraction, time-of-flight neutron powder diffraction, scanning-transmission electron microscopy, and electron energy-loss spectroscopy. Our quantum-mechanical calculations and experimental characterizations show that the incorporation of the rare-earth cations significantly enhances the hole mobility and concentration which results in the drastic increase in the thermoelectric performance.

  17. Model of a generator end-winding cage

    International Nuclear Information System (INIS)

    Leger, A.C.; Fanton, J.P.; Davies, C.

    1994-09-01

    This document presents some studies concerning the vibratory characterization of particular structures called: generator end-winding cages. These structures are mainly made up of the endings of armature windings. The question of their good mechanical behaviour is of prime importance, since they are submitted to high electromagnetic efforts during the different electrical ratings encountered during operation. The designer (GEC-Alsthom) and the user (EDF) have both undertaken numerical calculations in order to characterize a given machine, in this case a 600 MW bipolar generator; it appeared interesting to compare such calculations. The models realized respectively by GEC-Alsthom and EDF make use of different techniques and hypotheses. GEC-Alsthom represents the sets of rods and spacers by plates, which properties are determined by a pre-processor. The model is simplified to take into account the existing symmetries. It takes profit of previous experience and aims at a fast utilisation. The EDF model tends to allow a further comprehensive calculation, form the electromagnetic efforts to the determination of local stresses. The whole set of the constituting elements of the structure is modelled by beams, which leads to an important size for the model (21 000 degrees of freedom). The validation performed on the two models has been focused on the comparison between respective results and also with experimental results. Each model provides values for the first eigenfrequencies and the associated modes shapes. (authors). 3 refs., 3 figs., 2 tabs

  18. Closed-cage tungsten oxide clusters in the gas phase.

    Science.gov (United States)

    Singh, D M David Jeba; Pradeep, T; Thirumoorthy, Krishnan; Balasubramanian, Krishnan

    2010-05-06

    During the course of a study on the clustering of W-Se and W-S mixtures in the gas phase using laser desorption ionization (LDI) mass spectrometry, we observed several anionic W-O clusters. Three distinct species, W(6)O(19)(-), W(13)O(29)(-), and W(14)O(32)(-), stand out as intense peaks in the regular mass spectral pattern of tungsten oxide clusters suggesting unusual stabilities for them. Moreover, these clusters do not fragment in the postsource decay analysis. While trying to understand the precursor material, which produced these clusters, we found the presence of nanoscale forms of tungsten oxide. The structure and thermodynamic parameters of tungsten clusters have been explored using relativistic quantum chemical methods. Our computed results of atomization energy are consistent with the observed LDI mass spectra. The computational results suggest that the clusters observed have closed-cage structure. These distinct W(13) and W(14) clusters were observed for the first time in the gas phase.

  19. Structure and assembly of scalable porous protein cages

    Science.gov (United States)

    Sasaki, Eita; Böhringer, Daniel; van de Waterbeemd, Michiel; Leibundgut, Marc; Zschoche, Reinhard; Heck, Albert J. R.; Ban, Nenad; Hilvert, Donald

    2017-03-01

    Proteins that self-assemble into regular shell-like polyhedra are useful, both in nature and in the laboratory, as molecular containers. Here we describe cryo-electron microscopy (EM) structures of two versatile encapsulation systems that exploit engineered electrostatic interactions for cargo loading. We show that increasing the number of negative charges on the lumenal surface of lumazine synthase, a protein that naturally assembles into a ~1-MDa dodecahedron composed of 12 pentamers, induces stepwise expansion of the native protein shell, giving rise to thermostable ~3-MDa and ~6-MDa assemblies containing 180 and 360 subunits, respectively. Remarkably, these expanded particles assume unprecedented tetrahedrally and icosahedrally symmetric structures constructed entirely from pentameric units. Large keyhole-shaped pores in the shell, not present in the wild-type capsid, enable diffusion-limited encapsulation of complementarily charged guests. The structures of these supercharged assemblies demonstrate how programmed electrostatic effects can be effectively harnessed to tailor the architecture and properties of protein cages.

  20. Speed Control of Multiphase Cage Induction Motors Incorporating Supply Sequence

    Directory of Open Access Journals (Sweden)

    Drozdowski Piotr

    2014-12-01

    Full Text Available The subject of this paper is the control possibility of the multiphase cage induction motors having number of phases greater than 3. These motors have additional properties for speed control that distinguish them from the standard 3 phase motors: operation at various sequences of supplying voltages due to the inverter control and possible operation with few open-circuited phases. For each supply sequence different no load speeds at the same frequency can be obtained. This feature extends the motor application for miscellaneous drive demands including vector or scalar control. This depends mainly on the type of the stator winding for a given number of phases, since the principle of motor operation is based on co-operation of higher harmonics of magnetic field. Examples of operation are presented for a 9-phase motor, though general approach has been discussed. This motor was fed by a voltage source inverter at field oriented control with forced currents. The mathematical model of the motor was reduced to the form incorporating all most important physical features and appropriate for the control law formulation. The operation was illustrated for various supply sequences for “healthy” motor and for the motor operating at one phase broken. The obtained results have shown that parasitic influence of harmonic fields interaction has negligible influence on motor operation with respect to the useful coupling for properly designed stator winding.

  1. John Cage's Aria viewed through the prism of contextual determination

    Directory of Open Access Journals (Sweden)

    Radovanović Bojana

    2017-01-01

    Full Text Available The paper analysis the three contextual layers of creating John Cage's Aria for solo voice performed by Cathy Berberia at the 'big stage' of musical neo-avant-garde in Darmstadt. The layers in question are: (1 the socio-political context of Germany after World War II, where the denazification process was started at the time, (2 the artistic context of neo-avant-garde musical milieu which was being formed in Darmstadt in that period, and (3 the context of a new epoch in the history of vocal art. The thesis presented here is that an encounter occurred between American experimental and European avant-garde musical practice during the accelerated denazification and liberalisation of German society and the establishment of the Cold War relationship between the East and the West. The piece Aria represents an example of a collaborative work between American and European artists, which turned to be an important step in the history of extended vocal techniques in musical performing and composing.

  2. Porous organic cage membranes for water desalination: a simulation exploration.

    Science.gov (United States)

    Kong, Xian; Jiang, Jianwen

    2017-07-19

    Porous organic cages (POCs) have emerged as a new class of porous materials and received considerable interest for their potential applications. Herein we report the first proof-of-concept simulation study on POC membranes for water desalination. Five [4+6] POCs (CC1, CC2, CC3, CC16, and CC17) are considered with similar crystal structures, but different periphery groups and pore morphologies. CC1 is found to be impermeable to water due to disconnected pores. With an interconnected tetrahedral pore network, CC3 and CC16 have an intermediate water permeability of 1-5 × 10 -7 kg m (m 2 h bar) -1 . CC2 and CC17 contain straight pores and a widely open pore network, respectively, thus exhibit a high water permeability of 2-3 × 10 -6 kg m (m 2 h bar) -1 ; nevertheless, salt rejection in CC17 is only 89%. Among the five POC membranes, CC2 is the best for water desalination with performance superior to other membranes reported in the literature. The membrane flexibility is revealed to have a weak effect on water permeation. To provide further microscopic understanding, the permeation duration, diffusion and hydrogen bonding of water in the POC membranes are quantitatively analyzed. From this simulation study, the key factors governing water permeation in the POC membranes are unraveled and CC2 is identified to be an interesting candidate for water desalination.

  3. Four-dimensional multi-site photolysis of caged neurotransmitters

    Directory of Open Access Journals (Sweden)

    Mary Ann eGo

    2013-12-01

    Full Text Available Neurons receive thousands of synaptic inputs that are distributed in space and time. The systematic study of how neurons process these inputs requires a technique to stimulate multiple yet highly targeted points of interest along the neuron's dendritic tree. Three-dimensional multi-focal patterns produced via holographic projection combined with two-photon photolysis of caged compounds can provide for highly localized release of neurotransmitters within each diffraction-limited focus, and in this way emulate simultaneous synaptic inputs to the neuron. However, this technique so far cannot achieve time-dependent stimulation patterns due to fundamental limitations of the hologram-encoding device and other factors that affect the consistency of controlled synaptic stimulation. Here, we report an advanced technique that enables the design and application of arbitrary spatio-temporal photostimulation patterns that resemble physiological synaptic inputs. By combining holographic projection with a programmable high-speed light-switching array, we have overcome temporal limitations with holographic projection, allowing us to mimic distributed activation of synaptic inputs leading to action potential generation. Our experiments uniquely demonstrate multi-site two-photon glutamate uncaging in three dimensions with submillisecond temporal resolution. Implementing this approach opens up new prospects for studying neuronal synaptic integration in four dimensions.

  4. Study on Soft Phase Locked Method to Solving the Synchronization Problem of Active Power Filter in Stand-alone Power Grid

    DEFF Research Database (Denmark)

    Zhuo, Fang; Wu, Longhui; Chen, Zhe

    2009-01-01

    on zero-cross detection can't work effectively in small rating stand-alone power grid. Then a soft phase locked loop with additional filter is proposed. It can lock the phase angle on to the positive sequence of fundamental voltage accurately and rapidly. It ensures the performance of APF applied...... in the small rating stand-alone power grid. Moreover, the soft phase locked loop is easy to be implemented in a Digital Signal Processor (DSP). Simulation and experimental results validate that the soft phase locked loop has satisfactory performance.......Traditional LC filters can't work stably in small rating stand-alone power grid. So active power filter (APF) is becoming an important tool to solve the power quality problem in small rating stand-alone power grid. In most current detection algorithm of APF, it needs a synchronizing signal. Firstly...

  5. Progesterone after Estradiol Modulates Shuttle-Cage Escape by Facilitating Volition

    Directory of Open Access Journals (Sweden)

    Darryl J. Mayeaux

    2015-01-01

    Full Text Available In animal models of depression, depression is defined as performance on a learning task. That task is typically escaping a mild electric shock in a shuttle cage by moving from one side of the cage to the other. Ovarian hormones influence learning in other kinds of tasks, and these hormones are associated with depressive symptoms in humans. The role of these hormones in shuttle-cage escape learning, however, is less clear. This study manipulated estradiol and progesterone in ovariectomized female rats to examine their performance in shuttle-cage escape learning without intentionally inducing a depressive-like state. Progesterone, not estradiol, within four hours of testing affected latencies to escape. The improvement produced by progesterone was in the decision to act, not in the speed of learning or speed of escaping. This parallels depression in humans in that depressed people are slower in volition, in their decisions to take action.

  6. Perioperative complications in patients treated with posterior cervical fusion and bilateral cages

    Directory of Open Access Journals (Sweden)

    Krzysztof B Siemionow

    2017-01-01

    Conclusions: The results of our study show that PCF with cages can be considered a safe alternative for patients undergoing cervical spine surgery. The procedure has a favorable overall complication profile, short length of stay, and negligible blood loss.

  7. Direct gravimetric sensing of GBL by a molecular recognition process in organic cage compounds.

    Science.gov (United States)

    Brutschy, Malte; Schneider, Markus W; Mastalerz, Michael; Waldvogel, Siegfried R

    2013-09-28

    Organic cages were identified as highly potent affinity materials for the tracing of γ-butyrolactone. The selectivity over ethanol and water is based on the interior functional groups which allow preferential hydrogen bonding to the target analyte.

  8. Reducing organic contamination of shallow areas in brackish lagoons during rearing fish in cages in polyculture

    Directory of Open Access Journals (Sweden)

    P. Shekk

    2017-07-01

    Full Text Available Purpose. The development of the technology of the controlled rearing of marine fish remains one of the priority strategic trends of development of national mariculture. A study of the possibility of using polyculture for cage culture has a particular interest. Joint cultivation of several species of fish in the same cage, as practice of fish farming has demonstrated, does not have a tangible positive effect. At the same time, the use of cages of special design can provide significant additional fish products through the use of additional aquaculture objects. The ecological state of water areas, where the cages are located, is of great importance. High fish stocking density and the use of artificial feeds can serve as a source of powerful biogenic and organic pollution, which is especially important for shallow water areas with weak water exchange. The purpose of the study is to develop the methods for joint fish production in cage mariculture capable to provide high fish production and to weaken organic pollution of shallow water areas where cage farms are located. Methodology. The studies were conducted in 1999 and 2004. Cages of special design (internal 10 m3 and external 18.75 m3 installed in the brackish Shabolat Lagoon were used for rearing, steelhead trout, haarder, grass goby and round goby in polyculture. The standard aquaculture research methods were used. For express-analysis of environment hydrochemical parameters in cage location area the following devices were used: "ECOTEST-2000 T" (О2, NO2, NO3, NH4, CO2, phosphates, pH; termooksimetr "АJА-101М" (Т; О2; "pH meter-150 M; Refractometer "ATAGO-100" (salinity and water density. Findings. The results of marine fish cultivation in cages in polyculture in the shallow Shabolat lagoon are presented. It has been shown that joint cultivation of salmon, mullet and gobies in specially designed cages in shallow marine lagoons allows using artificial and natural feeds more fully and

  9. Dye-sensitization of CdS nano-cage - A density functional theory approach

    International Nuclear Information System (INIS)

    Jain, Kalpna; Singh, Kh. S.; Kishor, Shyam; Josefsson, Ida; Odelius, Michael; Ramaniah, Lavanya M.

    2016-01-01

    Quantum dots a few nanometer in size exhibit unique properties in comparison to bulk due to quantum confinement. Their properties can be tuned according to their sizes. Dye sensitized quantum dot (DSQD) solar cells are based on the same principle with surface dangling bonds as a challenge. Researches have shown the existence and stability of nano-cages which are assembled such as to minimize the surface dangling bonds and hence maximize stability. Here, we report a first principles DFT study of optical and electronic properties of CdS-cage (Cd 34 S 34 ) sensitized with nkx-2388 dye in three different geometric configurations of dye attachment. A significant distortion is found to occur in the geometric structure of the cage when it interacts strongly with the dye. The relative positioning of dye and cage energy levels is found to be different in different configurations. The absorption spectrum has been analyzed with the help of natural transition orbitals (NTO).

  10. Food consumption and food exchange of caged honey bees using a radioactive labelled sugar solution

    Science.gov (United States)

    Libor, Anika; Kupelwieser, Vera; Crailsheim, Karl

    2017-01-01

    We measured the distribution of sugar solution within groups of caged honey bees (Apis mellifera) under standard in vitro laboratory conditions using 14C polyethylene glycol as a radioactive marker to analyze ingestion by individual bees after group feeding. We studied the impact of different experimental setups by varying the number of bees, age of bees, origin of bees, duration of experiment, the amount of available diet, and the influence of the neurotoxic pesticide imidacloprid in the diet on the feeding and food sharing behavior (trophallaxis). Sugar solution was non-uniformly distributed in bees in 36 out of 135 cages. As a measure of the extent to which the sugar diet was equally distributed between caged bees, we calculated the (inner 80%) intake ratio by dividing the intake of the 90th percentile bee by the intake of the 10th percentile bee. This intake ratio ranged from 1.3 to 94.8 in 133 individual cages, further supporting a non-uniform distribution of food among caged bees. We can expect a cage with 10 or 30 bees containing one bee that ingests, on average, the 8.8-fold of the bee in the same cage ingesting the smallest quantity of food. Inner 80% intake ratios were lower in experiments with a permanent or chronic offering of labelled sugar solution compared to temporary or acute feedings. After pooling the data of replicates to achieve a higher statistical power we compared different experimental setups. We found that uniform food distribution is best approached with 10 newly emerged bees per cage, which originate from a brood comb from a single colony. We also investigated the trophallaxis between caged honey bees which originally consumed the diet and newly added bees. Color marked bees were starved and added to the cages in a ratio of 10:5 or 20:20 after the initial set of bees consumed all the labelled sugar solution. The distribution of the labelled sugar solution by trophallaxis within 48 hours to added bees was 25% (10:5) or 45% (20:20) of the

  11. Food consumption and food exchange of caged honey bees using a radioactive labelled sugar solution.

    Directory of Open Access Journals (Sweden)

    Robert Brodschneider

    Full Text Available We measured the distribution of sugar solution within groups of caged honey bees (Apis mellifera under standard in vitro laboratory conditions using 14C polyethylene glycol as a radioactive marker to analyze ingestion by individual bees after group feeding. We studied the impact of different experimental setups by varying the number of bees, age of bees, origin of bees, duration of experiment, the amount of available diet, and the influence of the neurotoxic pesticide imidacloprid in the diet on the feeding and food sharing behavior (trophallaxis. Sugar solution was non-uniformly distributed in bees in 36 out of 135 cages. As a measure of the extent to which the sugar diet was equally distributed between caged bees, we calculated the (inner 80% intake ratio by dividing the intake of the 90th percentile bee by the intake of the 10th percentile bee. This intake ratio ranged from 1.3 to 94.8 in 133 individual cages, further supporting a non-uniform distribution of food among caged bees. We can expect a cage with 10 or 30 bees containing one bee that ingests, on average, the 8.8-fold of the bee in the same cage ingesting the smallest quantity of food. Inner 80% intake ratios were lower in experiments with a permanent or chronic offering of labelled sugar solution compared to temporary or acute feedings. After pooling the data of replicates to achieve a higher statistical power we compared different experimental setups. We found that uniform food distribution is best approached with 10 newly emerged bees per cage, which originate from a brood comb from a single colony. We also investigated the trophallaxis between caged honey bees which originally consumed the diet and newly added bees. Color marked bees were starved and added to the cages in a ratio of 10:5 or 20:20 after the initial set of bees consumed all the labelled sugar solution. The distribution of the labelled sugar solution by trophallaxis within 48 hours to added bees was 25% (10:5 or 45

  12. Food consumption and food exchange of caged honey bees using a radioactive labelled sugar solution.

    Science.gov (United States)

    Brodschneider, Robert; Libor, Anika; Kupelwieser, Vera; Crailsheim, Karl

    2017-01-01

    We measured the distribution of sugar solution within groups of caged honey bees (Apis mellifera) under standard in vitro laboratory conditions using 14C polyethylene glycol as a radioactive marker to analyze ingestion by individual bees after group feeding. We studied the impact of different experimental setups by varying the number of bees, age of bees, origin of bees, duration of experiment, the amount of available diet, and the influence of the neurotoxic pesticide imidacloprid in the diet on the feeding and food sharing behavior (trophallaxis). Sugar solution was non-uniformly distributed in bees in 36 out of 135 cages. As a measure of the extent to which the sugar diet was equally distributed between caged bees, we calculated the (inner 80%) intake ratio by dividing the intake of the 90th percentile bee by the intake of the 10th percentile bee. This intake ratio ranged from 1.3 to 94.8 in 133 individual cages, further supporting a non-uniform distribution of food among caged bees. We can expect a cage with 10 or 30 bees containing one bee that ingests, on average, the 8.8-fold of the bee in the same cage ingesting the smallest quantity of food. Inner 80% intake ratios were lower in experiments with a permanent or chronic offering of labelled sugar solution compared to temporary or acute feedings. After pooling the data of replicates to achieve a higher statistical power we compared different experimental setups. We found that uniform food distribution is best approached with 10 newly emerged bees per cage, which originate from a brood comb from a single colony. We also investigated the trophallaxis between caged honey bees which originally consumed the diet and newly added bees. Color marked bees were starved and added to the cages in a ratio of 10:5 or 20:20 after the initial set of bees consumed all the labelled sugar solution. The distribution of the labelled sugar solution by trophallaxis within 48 hours to added bees was 25% (10:5) or 45% (20:20) of the

  13. Exterior egg quality as affected by enrichment resources layout in furnished laying-hen cages.

    Science.gov (United States)

    Li, Xiang; Chen, Donghua; Meng, Fanyu; Su, Yingying; Wang, Lisha; Zhang, Runxiang; Li, Jianhong; Bao, Jun

    2017-10-01

    This study aimed to investigate the effects of enrichment resources (a perch, dustbath, and nest) layout in furnished laying-hen cages (FC) on exterior quality of eggs. One hundred and sixty-eight (168) Hy-Line Brown laying hens at 16 weeks of age were randomly distributed to four treatments: small furnished cages (SFC), medium furnished cages type I (MFC-I), medium furnished cages type II (MFC-II), and medium furnished cages type III (MFC-III). Each treatment had 4 replicates or cages with 6 hens for SFC (24 birds for each SFC) and 12 hen/cage for MFC-I, -II, and -III (48 birds for each MFC-I, -II and -III). Following a 2-week acclimation, data collection started at 18 weeks of age and continued till 52 weeks of age. Dirtiness of egg surface or cracked shell as indicators of the exterior egg quality were recorded each week. The results showed that the proportion of cracked or dirty eggs was significantly affected by the FC type (p<0.01) in that the highest proportion of cracked or dirty eggs was found in MFC-I and the lowest proportion of dirty eggs in SFC. The results of this showed that furnished cage types affected both dirty eggs and cracked eggs (p<0.01). The results also indicated that not nest but dustbath lead to more dirty eggs. Only MFC-I had higher dirty eggs at nest than other FC (p< 0.01). The results of dirty eggs in MFC-I and MFC-II compared with SFC and MFC-III seemed suggest that a low position of dustbath led to more dirty eggs. SFC design affected exterior egg quality and the low position of dustbath in FC resulted in higher proportion of dirty eggs.

  14. [The finite element analysis of polyetheretherketone/hydroxyapatite/carbon fiber cage].

    Science.gov (United States)

    Liu, Xueyong; Zhu, Hongxin; Jing, Yanfeng; Sui, Guoxin; Zhang, Zongfu

    2013-08-01

    To compare the bio-mechanical characteristics of cages of two types, i. e., polyetheretherketone/ hydroxyapatite/carbon fiber (PEEK/HA/CF) and titanium combined with internal pedicle screw fixation in lumbar model, and to provide experimental evidences for clinical application, we constructed a three-dimensional finite element model of an intact L2-L4 segment by using computer tomography scans of a healthy male. The three-dimensional finite element models of an intact L2-L4 segment and single cage plus bilateral vertebral pedicle screw fixation were established. The angular motion of fused segment and stress distribution in the bone graft and cage and L3 inferior endplate under different loads were recorded. The result showed that the peak Von Mises stresses of the bone graft of PEEK/HA/CF group were at least 2.2 time as that of titanium group. The peak Von Mises stresses of L3 inferior endplate of the titanium group were at least 2. 3 times as that of PEEK/HA/CF group. These stresses were concentrated at places where the cage interfaced with the endplate. The angular variation of the titanium group showed similarity to PEEK/HA/CF group. The PEEK/HA/CF cage could provide stability similar to that of titanium cage in the presence of posterior instrumentation. It could increase the load transfer through the bone graft and promote the bone fusion. It could also reduce the stresses in endplates adjacent to the cage and reduce the subsidence of the cage.

  15. A practical guide to the synthesis of dinitroindolinyl-caged neurotransmitters

    OpenAIRE

    Ellis-Davies, Graham C R

    2011-01-01

    This protocol describes a method for efficient chemical synthesis of dinitroindolinyl derivatives of glutamate and gamma-aminobutyric acid. these caged neurotransmitters are currently the most chemically and photochemically efficient probes for two-photon photolysis in living brain slices. the protocol only requires basic organic synthesis equipment, and no silica gel column chromatography or NMR spectroscopy is needed at any stage. Hplc is used to purify the caged transmitters at the end of ...

  16. Late Results of Anterior Cervical Discectomy and Fusion with Interbody Cages

    OpenAIRE

    Da?l?, Murat; Er, Uygur; ?im?ek, Serkan; Bavbek, Murad

    2013-01-01

    Study Design Retrospective analysis. Purpose To evaluate the effectiveness of anterior cervical discectomy with fusion for degenerative cervical disc disease. Overview of Literature Anterior spinal surgery originated in the mid-1950s and graft for fusion was also employed. Currently anterior cervical microdiscectomy and fusion with an intervertebral cage is a widely accepted procedure for treatment of cervical disc hernia. Artificial grafts and cages for fusion are preferred because of their ...

  17. Comparison of polyetheretherketone (PEEK) cage and cervical disc prostheses used in anterior cervical microscopic discectomy operations

    OpenAIRE

    Bahadir Alkan; Murat Cosar; Mustafa Guven; Adem Bozkurt Aras; Tarik Akman

    2017-01-01

    Objective: The aim of this study was to radiologically and clinically compare the polyetheretherketone (PEEK) cage and cervical disc prostheses used in anterior cervical microdiscectomy operations during the postoperative period. Methods: The study evaluated 25 cervical disc hernia patients. The cervical disc prosthesis group (Group A) comprised 10 patients while the PEEK cage group (Group B) comprised 15 patients. Before and after the operation, the cervical graphics from radiological mon...

  18. Characteristics Of Smoked Catfish (Hemibagrus Nemurus) Prepared Frompond Culture, Cage And Wild Fish

    OpenAIRE

    Maskilin, Jippo; Hasan, Bustari; Leksono, Tjipto

    2017-01-01

    This study was aimed to evaluate the sensory quality, proximate composition, amino acids and fatty acids profiles of smoked catfish prepared from pond, cage culture and wild fish. Catfish samples 300-350 grams in weight wastaken respectualy from wild (Kampar river), pond and cage culture in Sungai Paku, Kampar. The fish was smoked using hot smoking method, and the smoked fish was evaluated for smoking yield, sensory quality, proximate composition, amino acid and fatty acid profile.The smoking...

  19. Effects of interaction of breed by pen and cage position on hen day ...

    African Journals Online (AJOL)

    in which Pen location was designated as ' L' and mean cage position as 'C',the mean hen day lay of the breeds were estimated in percentages. This were subjected to a two way Analysis of variance to determine the effect of breed by pen and cage interaction on hen-day performance.Mean hen day lay of Haco black by pen ...

  20. A stand-alone demography and landscape structure module for Earth system models

    Science.gov (United States)

    Nieradzik, L. P.; Haverd, V.; Smith, B.; Cook, G. D.; Briggs, P.; Roxburgh, S.; Liedloff, A.; Meyer, C.; Canadell, J.

    2013-12-01

    component of any LSM, represents a significant advance in our ability to use in-situ and remotely sensed observations of biomass and individual level parameters (e.g. crown-size, tree-height, stem diameter) as constraints on the terrestrial carbon cycle. Haverd, V., B. Smith, G. Cook, P. Briggs, L. Nieradzik, S. Roxburgh, A. Liedloff, C. Meyer, and J. G. Canadell, A stand-alone tree demography and landscape structure module for Earth system models, submitted to Geophys. Res. Let., 2013 Wolf, A., P. Ciais, V. Bellassen, N. Delbart, C.B. Field, and J.A. Berry, Forest biomass allometry in global land surface models, Global Biogeochem. Cycles, 25, GB3015, doi:10.1029/2010GB003917, 2011

  1. Effects of Metabolic Cage Housing on Rat Behavior and Performance in the Social Interaction Test.

    Science.gov (United States)

    Whittaker, Alexandra L; Lymn, Kerry A; Howarth, Gordon S

    2016-01-01

    Although the metabolic cage is commonly used for housing nonhuman animals in the laboratory, it has been recognized as constituting a unique stressor. Such an environment would be expected to affect behavioral change in animals housed therein. However, few studies have specifically addressed the nature or magnitude of this change. The current study sought to characterize the behavioral time budget of rats in metabolic cage housing in comparison to that of individually housed animals in standard open-top cages. Rats in metabolic cages spent less time moving, manipulating enrichment, and carrying out rearing behaviors, and there was a corresponding shift toward inactivity. In an applied Social Interaction Test, behavioral scoring implied that metabolic cage housing had an anxiogenic effect. In conclusion, metabolic cage housing produces measurable effects on spontaneous and evoked behavior in rats in the laboratory. These behavioral changes may lead to a negative emotional state in these animals, which could have negative welfare consequences. Further research is needed to quantify the existence and magnitude of such an effect on rat well being.

  2. Evaluation of cage designs and feeding regimes for honey bee (Hymenoptera: Apidae) laboratory experiments.

    Science.gov (United States)

    Huang, Shao Kang; Csaki, Tamas; Doublet, Vincent; Dussaubat, Claudia; Evans, Jay D; Gajda, Anna M; Gregorc, Alex; Hamilton, Michele C; Kamler, Martin; Lecocq, Antoine; Muz, Mustafa N; Neumann, Peter; Ozkirim, Asli; Schiesser, Aygün; Sohr, Alex R; Tanner, Gina; Tozkar, Cansu Ozge; Williams, Geoffrey R; Wu, Lyman; Zheng, Huoqing; Chen, Yan Ping

    2014-02-01

    The aim of this study was to improve cage systems for maintaining adult honey bee (Apis mellifera L.) workers under in vitro laboratory conditions. To achieve this goal, we experimentally evaluated the impact of different cages, developed by scientists of the international research network COLOSS (Prevention of honey bee COlony LOSSes), on the physiology and survival of honey bees. We identified three cages that promoted good survival of honey bees. The bees from cages that exhibited greater survival had relatively lower titers of deformed wing virus, suggesting that deformed wing virus is a significant marker reflecting stress level and health status of the host. We also determined that a leak- and drip-proof feeder was an integral part of a cage system and a feeder modified from a 20-ml plastic syringe displayed the best result in providing steady food supply to bees. Finally, we also demonstrated that the addition of protein to the bees' diet could significantly increase the level ofvitellogenin gene expression and improve bees' survival. This international collaborative study represents a critical step toward improvement of cage designs and feeding regimes for honey bee laboratory experiments.

  3. Comparison growth of Kappaphycus alvarezii (Rhodophyta, Solieriaceae cultivation in floating cage and longline in Indonesia

    Directory of Open Access Journals (Sweden)

    Ma’ruf Kasim

    2017-05-01

    Full Text Available Currently, cultivation using cages for Kappaphycus alvarezii was limited reported before. This study aims to reveal growth of K. alvarezii cultivated in floating cages and longline. The study was conducted in one of cultivation areas in Southeast Sulawesi, Indonesia. Total gross weight, propagule growth rate and specific growth rate were performing in this study. During our field experiment, total gross weight of K. alvarezii after 40 days, from 5 kg was growth to 22.5 ± 1.40 kg and 38.8 ± 1.6 kg on longline and floating cages, respectively. Propagule growth rate after 40 days, from 50 g was 107.8 ± 7.0 g and 152.5 ± 7.9 g during April, and 132.0 ± 8.0 g and 218.8 ± 8.6 g during August, on longline and floating cage, respectively. Specific growth rate of K. alvarezii was high during August, 2.43% day−1 and 3.69% day−1 cultivated in longline and floating cage, respectively. Propagule morphology was white and damage in 40% cultivated by longline and no damage by using floating cage particular in August and September while high dense of herbivorous fish surrounding the experimental sites.

  4. Mouse housing system using pressurized cages intraventilated by direct-current microfans.

    Science.gov (United States)

    Martinewski, Alexandre; Correia, Caio S C; de Souza, Nívea L; Merusse, José L B

    2012-03-01

    We performed the initial assessment of an alternative pressurized intraventilated (PIV) caging system for laboratory mice that uses direct-current microfans to achieve cage pressurization and ventilation. Twenty-nine pairs of female SPF BALB/c mice were used, with 19 experimental pairs kept in PIV cages and 10 control pairs kept in regular filter-top (FT) cages. Both groups were housed in a standard housing room with a conventional atmospheric control system. For both systems, intracage temperatures were in equilibrium with ambient room temperature. PIV cages showed a significant difference in pressure between days 1 and 8. Air speed (and consequently airflow rate) and the number of air changes hourly in the PIV cages showed decreasing trends. In both systems, ammonia concentrations increased with time, with significant differences between groups starting on day 1. Overall, the data revealed that intracage pressurization and ventilation by using microfans is a simple, reliable system, with low cost, maintenance requirements, and incidence of failures. Further experiments are needed to determine the potential influence of this system on the reproductive performance and pulmonary integrity in mice.

  5. Model of a generator end-winding cage; Modelisation d`une cage de developpantes d`alternateur

    Energy Technology Data Exchange (ETDEWEB)

    Leger, A.C.; Fanton, J.P.; Davies, C.

    1994-09-01

    This document presents some studies concerning the vibratory characterization of particular structures called: generator end-winding cages. These structures are mainly made up of the endings of armature windings. The question of their good mechanical behaviour is of prime importance, since they are submitted to high electromagnetic efforts during the different electrical ratings encountered during operation. The designer (GEC-Alsthom) and the user (EDF) have both undertaken numerical calculations in order to characterize a given machine, in this case a 600 MW bipolar generator; it appeared interesting to compare such calculations. The models realized respectively by GEC-Alsthom and EDF make use of different techniques and hypotheses. GEC-Alsthom represents the sets of rods and spacers by plates, which properties are determined by a pre-processor. The model is simplified to take into account the existing symmetries. It takes profit of previous experience and aims at a fast utilisation. The EDF model tends to allow a further comprehensive calculation, form the electromagnetic efforts to the determination of local stresses. The whole set of the constituting elements of the structure is modelled by beams, which leads to an important size for the model (21 000 degrees of freedom). The validation performed on the two models has been focused on the comparison between respective results and also with experimental results. Each model provides values for the first eigenfrequencies and the associated modes shapes. (authors). 3 refs., 3 figs., 2 tabs.

  6. Analysis and interpretation of the model of a Faraday cage for electromagnetic compatibility testing

    Directory of Open Access Journals (Sweden)

    Nenad V. Munić

    2014-02-01

    Full Text Available In order to improve the work of the Laboratory for Electromagnetic Compatibility Testing in the Technical Test Center (TTC, we investigated the influence of the Faraday cage on measurement results. The primary goal of this study is the simulation of the fields in the cage, especially around resonant frequencies, in order to be able to predict results of measurements of devices under test in the anechoic chamber or in any other environment. We developed simulation (computer models of the cage step by step, by using the Wipl-D program and by comparing the numerical results with measurements as well as by resolving difficulties due to the complex structure and imperfections of the cage. The subject of this paper is to present these simulation models and the corresponding results of the computations and measurements. Construction of the cage The cage is made of steel plates with the dimensions 1.25 m x 2.5 m. The base of the cage is a square; the footprint interior dimensions are 3.76 m x 3.76 m, and the height is 2.5 m. The cage ceiling is lowered by plasticized aluminum strips. The strips are loosely attached to the carriers which are screwed to the ceiling. The cage has four ventilation openings (two on the ceiling and two on one wall, made of honeycomb waveguide holes. In one corner of the cage, there is a single door with springs made of beryllium bronze. For frequencies of a few tens of MHz, the skin effect is fully developed in the cage walls. By measuring the input impedance of the wire line parallel to a wall of the cage, we calculated the surface losses of the cage plates. In addition, we used a magnetic probe to detect shield discontinuities. We generated a strong current at a frequency of 106 kHz outside the cage and measured the magnetic field inside the cage at the places of cage shield discontinuities. In this paper, we showed the influence of these places on the measurement results, especially on the qualitative and quantitative

  7. Biologic activity of cyclic and caged phosphates: a review.

    Science.gov (United States)

    Lorke, Dietrich E; Stegmeier-Petroianu, Anka; Petroianu, Georg A

    2017-01-01

    The recognition in the early 1960s by Morifusa Eto that tri-o-cresyl phosphate (TOCP) is hydroxylated by the cytochrome P450 system to an intermediate that spontaneously cyclizes to a neurotoxic phosphate (saligenin phosphate ester) ignited the interest in this group of compounds. Only the ortho isomer can cyclize and clinically cause Organo Phosphate Induced Delayed Neurotoxicity (OPIDN); the meta and para isomers of tri-cresyl phosphate are not neuropathic because they are unable to form stable cyclic saligenin phosphate esters. This review identifies the diverse biological effects associated with various cyclic and caged phosphates and phosphonates and their possible use. Cyclic compounds that inhibit acetylcholine esterase (AChE), such as salithion, can be employed as pesticides. Others are neurotoxic, most probably because of inhibition of neuropathy target esterase (NTE). Cyclic phosphates that inhibit lipases, the cyclipostins, possibly represent promising therapeutic avenues for the treatment of type 2 diabetes mellitus and/or microbial infections; those compounds inhibiting β-lactamase may prevent bacterial resistance against β-lactam antibiotics. Naturally occurring cyclic phosphates, such as cyclic AMP, cyclic phosphatidic acid and the ryanodine receptor modulator cyclic adenosine diphosphate ribose, play an important physiological role in signal transduction. Moreover, some cyclic phosphates are GABA-antagonists, while others are an essential component of Molybdenum-containing enzymes. Some cyclic phosphates (cyclophosphamide, ifosfamide) are clinically used in tumor therapy, while the coupling of therapeutic agents with other cyclic phosphates (HepDirect® Technology) allows drugs to be targeted to specific organs. Possible clinical applications of these compounds are considered. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  8. Impact of sea waves on underwater fish-breeding cages

    Directory of Open Access Journals (Sweden)

    Pilyaev Sergey Ivanovich

    2014-02-01

    Full Text Available Cultivation of sea objects is of great importance while solving the problems of providing the constantly growing requirements of the national economy with sea products. Cultivation of sea objects uses special hydrobiotechnical constructions. As the practice showed, cultivation of seafood is commercially impossible without solving the questions of calculating and designing such constructions. In special literature these questions are poorly covered or not considered at all. In the article the results of theoretical and pilot studies of waves influence on hydrobiotechnical constructions is provided, in particular on underwater fish-breeding cages.This article offers the theoretical solution to the problem of determining the efforts of the ropes holding the fish tank under wave influences. In order to solve this problem, the equations of hard drives movements were set up and the differential equations of free oscillations of buzz were obtained.When determining the horizontal movements, the four different configurations of connections and the system motion directions in general are possible in case of waveoscillations. Next step is the solution of the differential equations and determination of natural oscillation frequency in the direction of the vertical axis. Defining efforts in the ropes from their own weight (static calculation is self-explanatory, it should be noted that accounting for the weighing influence of water on such structures does not have significant influence.Further the authors defined loading and efforts from the regular waves’ impacts.Modeling of the waves influence on submersible fish tank was carried by Fraud method. The studies were conducted with two models with large and small mesh. The signals of strain gauge sensors were registered by electronic measuring equipment.When comparing the theoretical and experimental data, satisfactory results have been obtained. It was determined that in order to improve the calculation

  9. Ferrimagnetic ferritin cage nanoparticles used as MRI contrast agent

    Science.gov (United States)

    Cai, Y.; Cao, C.; Zhang, T.; Xu, H.; Pan, Y.

    2017-12-01

    The nano-sized ferrimagnetic ferritin cage nanoparticles are ideal materials for understanding of superparamagnetism, biomimetic synthesis of ultrafine magnetic particles and their application in biomedicine. Ferrimagnetic M-HFn nanoparticles with size of magnetite cores in a mean size ranges from 2.7 nm to 5.3 nm were synthesized through loading different amount of iron into recombinant human H chain ferritin (HFn) shells. Both the saturation magnetization (Ms) and blocking temperature (Tb) were increased with the size of ferrimagnetic cores. In essence, magnetic resonance imaging (MRI) analysis showed that the synthesized M-HFn nanoparticles (5.3 nm magnetite core) has extremely high transverse relaxivity (r2) values up to 320.9 mM-1S-1, which indicate that M-HFn nanoparticles are promising negative contrast agent in early detection of tumors. In addition, the longitudinal relaxivity (r1) (10.4 mM-1S-1) and r2/r1 ratio ( 2.2) of M-HFn nanoparticles ( 2.7 nm magnetite core in diameter) will make it a considerable potential as a positive contrast agent in MRI. This means the M-HFn nanoparticles can be used as dual functional MR contrast agent. Acute toxicity study of M-HFn in rats showed that a dosage of 20 mg Fe/kg makes no abnormalities by serum biochemical and hematological analysis as well as histopathological examination. Compared with a similar commercial contrast agent, combidex (with a clinical dosage of 2.7 mg Fe/kg), it indicates that M-HFn nanoparticle is of a relative safe ferrimagnetic nanoparticle when used in vivo.

  10. Sea-cage aquaculture, sea lice, and declines of wild fish.

    Science.gov (United States)

    Frazer, L Neil

    2009-06-01

    A sea cage, sometimes referred to as a net pen, is an enclosure designed to prevent farm fish from escaping and to protect them from large predators, while allowing a free flow of water through the cage to carry away waste. Farm fish thus share water with wild fish, which enables transmission of parasites, such as sea lice, from wild to farm and farm to wild fishes. Sea lice epidemics, together with recently documented population-level declines of wild salmon in areas of sea-cage farming, are a reminder that sea-cage aquaculture is fundamentally different from terrestrial animal culture. The difference is that sea cages protect farm fish from the usual pathogen-control mechanisms of nature, such as predators, but not from the pathogens themselves. A sea cage thus becomes an unintended pathogen factory. Basic physical theory explains why sea-cage aquaculture causes sea lice on sympatric wild fish to increase and why increased lice burdens cause wild fish to decline, with extirpation as a real possibility. Theory is important to this issue because slow declines of wild fish can be difficult to detect amid large fluctuations from other causes. The important theoretical concepts are equilibrium, host-density effect, reservoir-host effect, and critical stocking level of farmed fish (stocking level at which lice proliferate on farm fish even if wild fish are not present to infect them). I explored these concepts and their implications without mathematics through examples from salmon farming. I also considered whether the lice-control techniques used by sea-cage farmers (medication and shortened grow-out times) are capable of protecting wild fish. Elementary probability showed that W ≈ W* - εF (where W is the abundance of wild fish, W* is the prefarm abundance, F is the abundance of farm fish, and ε is the ratio of lice per farm fish to lice per wild fish). Declines of wild fish can be reduced by short growing cycles for farm fish, medicating farm fish, and keeping

  11. Effect of cage type on the behaviour patterns of rabbit does at different physiological stages

    Directory of Open Access Journals (Sweden)

    Clara Alfonso-Carrillo

    2014-03-01

    Full Text Available Interest in commercially farmed rabbit welfare has increased in recent years. As a result, new alternativehousing systems have been developed, although they require evaluation in order to demonstrate their potential for improving welfare. The aim of this trial was to study the behavioural traits of rabbit does housed in 2 different types of cage (TC: conventional vs. alternative with an elevated platform, at different physiological stages (PS; lactation and gestation. Behavioural observations were carried out on 12 rabbit commercial does using continuous 24 h video recording. Independently of PS and TC, rabbit does spent most of their time on foot mats (on av. 57.7%. However, due to the use of platforms (on av. 23.0% of time, lactating does spent 36.6% less time on foot mats (P<0.001 and gestating does spent 27.0% less time on wire mesh (P<0.001 in alternative cages than in conventional cages. Alternative cages allowed for standing posture, but this behaviour was only observed in gestating does (on av. 4.6 times a day. Frequency of drinking was higher in conventional than in alternative cages (24.6 vs. 19.1 times a day; P<0.05. Gestating does housed in conventional cages reached the highest duration and frequency of interacting with neighbours (276 s/d and 4.6 times/d; P<0.05. The frequency of interacting with kits was lower in alternative than in conventional cages (2.4 vs. 8.6 times a day; P<0.01. Doe behaviour was influenced by the time of day, with less activity during the midday hours. During dark hours, rabbit does more frequently performed restless behaviour such as hyperactivity or nursing, matching the time at which rabbit does spent more time on the platform. The platform was frequently used by rabbit does, regardless of their physiological stage, and during late lactation phase, when mothers were not receptive to nursing, does housed in alternative cages used the platform as a mean to flee from kits trying to suckle

  12. Depopulation of Caged Layer Hens with a Compressed Air Foam System

    Science.gov (United States)

    Gurung, Shailesh; Hoffman, John; Stringfellow, Kendre; Abi-Ghanem, Daad; Zhao, Dan; Caldwell, David; Lee, Jason; Styles, Darrel; Berghman, Luc; Byrd, James; Farnell, Yuhua; Archer, Gregory

    2018-01-01

    Simple Summary Reportable diseases, such as avian influenza, spread rapidly among poultry, resulting in the death of a large number of birds. Once such a disease has been diagnosed at a farm, infected and susceptible birds are rapidly killed to prevent the spread of the disease. The methods to eliminate infected caged laying hens are limited. An experiment was conducted to study the effectiveness of foam made from compressed air, water, and soap to kill laying hens in cages. The study found that stress levels of the hens killed using compressed air foam in cages to be similar to the hens killed by carbon dioxide or the negative control. Hens exposed to carbon dioxide died earlier as compared to the foam methods. The authors conclude that application of compressed air foam in cages is an alternative to methods such as gas inhalation and ventilation shutdown to rapidly and humanely kill laying hens during epidemics. Abstract During the 2014–2015 US highly pathogenic avian influenza (HPAI) outbreak, 50.4 million commercial layers and turkeys were affected, resulting in economic losses of $3.3 billion. Rapid depopulation of infected poultry is vital to contain and eradicate reportable diseases like HPAI. The hypothesis of the experiment was that a compressed air foam (CAF) system may be used as an alternative to carbon dioxide (CO2) inhalation for depopulating caged layer hens. The objective of this study was to evaluate corticosterone (CORT) and time to cessation of movement (COM) of hens subjected to CAF, CO2 inhalation, and negative control (NEG) treatments. In Experiment 1, two independent trials were conducted using young and spent hens. Experiment 1 consisted of five treatments: NEG, CO2 added to a chamber, a CO2 pre-charged chamber, CAF in cages, and CAF in a chamber. In Experiment 2, only spent hens were randomly assigned to three treatments: CAF in cages, CO2 added to a chamber, and aspirated foam. Serum CORT levels of young hens were not significantly

  13. Hierarchical energy management system for stand-alone hybrid system based on generation costs and cascade control

    International Nuclear Information System (INIS)

    Torreglosa, J.P.; García, P.; Fernández, L.M.; Jurado, F.

    2014-01-01

    Highlights: • We present an energy management system for a stand-alone WT/PV/hydrogen/battery hybrid system. • Hierarchical control composed by master and slave control strategies. • Control assures reliable electricity support for stand-alone applications subject to technical and economic criteria. - Abstract: This paper presents an energy management system (EMS) for stand-alone hybrid systems composed by photovoltaic (PV) solar panels and a wind turbine (WT) as primary energy sources and two energy storage systems, which are a hydrogen system and a battery. The hydrogen system is composed of fuel cell (FC), electrolyzer and hydrogen storage tank. The EMS is a hierarchical control composed by a master control strategy and a slave control strategy. On the one hand, the master control generates the reference powers to meet several premises (such as to satisfy the load power demand, and to maintain the hydrogen tank level and the state of charge (SOC) of the battery between their target margins), taking also into account economic aspects to discriminate between using the battery or hydrogen system. On the other hand, the slave control modifies the reference powers generated by the master control according to the energy sources dynamic limitations, and maintains the DC bus voltage at its reference value. The models, implemented in MATLAB-Simulink environment, have been developed from commercially available components. To check the viability of the proposed EMS, two kinds of simulations were carried out: (1) A long-term simulation of 25 years (expected lifetime of the system) with a sample time of one hour to validate the master control of the EMS; and (2) A short-term simulation with sudden net power variations to validate the slave control of the EMS

  14. An optimized Fuzzy Logic Controller by Water Cycle Algorithm for power management of Stand-alone Hybrid Green Power generation

    International Nuclear Information System (INIS)

    Sarvi, Mohammad; Avanaki, Isa Nasiri

    2015-01-01

    Highlights: • A new method to improve the performance of renewable power management is proposed. • The proposed method is based on Fuzzy Logic optimized by the Water Cycle Algorithm. • The proposed method characteristics are compared with two other methods. • The comparisons confirm that the proposed method is robust and effectiveness one. - Abstract: This paper aims to improve the power management system of a Stand-alone Hybrid Green Power generation based on the Fuzzy Logic Controller optimized by the Water Cycle Algorithm. The proposed Stand-alone Hybrid Green Power consists of wind energy conversion and photovoltaic systems as primary power sources and a battery, fuel cell, and Electrolyzer as energy storage systems. Hydrogen is produced from surplus power generated by the wind energy conversion and photovoltaic systems of Stand-alone Hybrid Green Power and stored in the hydrogen storage tank for fuel cell later using when the power generated by primary sources is lower than load demand. The proposed optimized Fuzzy Logic Controller based power management system determines the power that is generated by fuel cell or use by Electrolyzer. In a hybrid system, operation and maintenance cost and reliability of the system are the important issues that should be considered in studies. In this regard, Water Cycle Algorithm is used to optimize membership functions in order to simultaneously minimize the Loss of Power Supply Probability and operation and maintenance. The results are compared with the particle swarm optimization and the un-optimized Fuzzy Logic Controller power management system to prove that the proposed method is robust and effective. Reduction in Loss of Power Supply Probability and operation and maintenance, are the most advantages of the proposed method. Moreover the level of the State of Charge of the battery in the proposed method is higher than other mentioned methods which leads to increase battery lifetime.

  15. A critical evaluation of deterministic methods in size optimisation of reliable and cost effective standalone hybrid renewable energy systems

    International Nuclear Information System (INIS)

    Maheri, Alireza

    2014-01-01

    Reliability of a hybrid renewable energy system (HRES) strongly depends on various uncertainties affecting the amount of power produced by the system. In the design of systems subject to uncertainties, both deterministic and nondeterministic design approaches can be adopted. In a deterministic design approach, the designer considers the presence of uncertainties and incorporates them indirectly into the design by applying safety factors. It is assumed that, by employing suitable safety factors and considering worst-case-scenarios, reliable systems can be designed. In fact, the multi-objective optimisation problem with two objectives of reliability and cost is reduced to a single-objective optimisation problem with the objective of cost only. In this paper the competence of deterministic design methods in size optimisation of reliable standalone wind–PV–battery, wind–PV–diesel and wind–PV–battery–diesel configurations is examined. For each configuration, first, using different values of safety factors, the optimal size of the system components which minimises the system cost is found deterministically. Then, for each case, using a Monte Carlo simulation, the effect of safety factors on the reliability and the cost are investigated. In performing reliability analysis, several reliability measures, namely, unmet load, blackout durations (total, maximum and average) and mean time between failures are considered. It is shown that the traditional methods of considering the effect of uncertainties in deterministic designs such as design for an autonomy period and employing safety factors have either little or unpredictable impact on the actual reliability of the designed wind–PV–battery configuration. In the case of wind–PV–diesel and wind–PV–battery–diesel configurations it is shown that, while using a high-enough margin of safety in sizing diesel generator leads to reliable systems, the optimum value for this margin of safety leading to a

  16. High-Efficiency Isolated Photovoltaic Microinverter Using Wide-Band Gap Switches for Standalone and Grid-Tied Applications

    Directory of Open Access Journals (Sweden)

    Yu-Chen Liu

    2018-03-01

    Full Text Available An isolated photovoltaic micro-inverter for standalone and grid-tied applications is designed and implemented to achieve high efficiency. System configuration and design considerations, including the proposed active-clamp forward-flyback resonant converter for the DC-DC stage and a dual-frequency full-bridge inverter for the DC-AC stage, are analyzed and discussed. A prototype microinverter system is built and tested. Experimental results verify the feasibility of the proposed system, which achieves 95% power conversion efficiency at full load.

  17. Optimization of a stand-alone Solar PV-Wind-DG Hybrid System for Distributed Power Generation at Sagar Island

    Science.gov (United States)

    Roy, P. C.; Majumder, A.; Chakraborty, N.

    2010-10-01

    An estimation of a stand-alone solar PV and wind hybrid system for distributed power generation has been made based on the resources available at Sagar island, a remote area distant to grid operation. Optimization and sensitivity analysis has been made to evaluate the feasibility and size of the power generation unit. A comparison of the different modes of hybrid system has been studied. It has been estimated that Solar PV-Wind-DG hybrid system provides lesser per unit electricity cost. Capital investment is observed to be lesser when the system run with Wind-DG compared to Solar PV-DG.

  18. Losses Evaluation for a Two-Level Three-Phase Stand-Alone Voltage Source Converter Using Model Predictive Control

    DEFF Research Database (Denmark)

    Al hasheem, Mohamed; Dragicevic, Tomislav; Rivera, Marco

    2017-01-01

    conventional and improved controller is conducted in terms of losses. The switching and conduction losses for the VSC are calculated using MATLAB/SIMULINK and PLECS software. A power level up to 1 kW is considered for the conventional and the improved schemes. All simulation and experimental results......This paper discusses a Model Predictive Control (MPC) scheme for a Voltage Source Converter (VSC) where the aim is to minimize losses and Total Harmonics distortion (THD) compared to the conventional MPC scheme. Different Cost Functions (CFs) are applied to the stand-alone VSC. A comparison between...

  19. Dynamic behavior of PEM FCPPs under various load conditions and voltage stability analysis for stand-alone residential applications

    Science.gov (United States)

    Uzunoglu, M.; Onar, O. C.; Alam, M. S.

    In this paper, dynamic behavior and performance of a fuel cell power plant (FCPP) which operates in parallel with a battery bank is tested under classified load conditions, such as mostly resistive, mostly inductive, resistive-inductive and non-linear loads. Thereafter, voltage stability analysis is performed using the dynamic response of the FCPP for stand-alone residential applications. Simulation results are obtained using the MATLAB ® and Simulink ® software packages, based on the mathematical and dynamic electrical models of the system. Using the experimental results, a validated model has been realized and voltage stability analysis is performed through this model.

  20. Effect of space allowance and cage size on laying hens housed in furnished cages, Part I: Performance and well-being

    Science.gov (United States)

    Widowski, T. M; Caston, L. J; Hunniford, M. E; Cooley, L; Torrey, S

    2017-01-01

    Abstract There are few published data on the effects of housing laying hens at different densities in large furnished cages (FC; a.k.a. enriched colony cages). The objective of this study was to determine the effects of housing laying hens at 2 space allowances (SA) in 2 sizes of FC on measures of production and well-being. At 18 wk of age, 1,218 LSL-Lite hens were housed in cages furnished with a curtained nesting area, perches, and scratch mat, and stocked at either 520 cm2 (Low) or 748 cm2 (High) total floor space. This resulted in 4 group sizes: 40 vs. 28 birds in smaller FC (SFC) and 80 vs. 55 in larger FC (LFC). Data were collected from 20 to 72 wks of age. There was no effect of cage size (P = 0.21) or SA (P = 0.37) on hen day egg production, egg weight (PSize = 0.90; PSA = 0.73), or eggshell deformation (PSize = 0.14; PSA = 0.053), but feed disappearance was higher in SFC than LFC (P = 0.005). Mortality to 72 wk was not affected by cage size (P = 0.78) or SA (P = 0.55). BW (P = 0.006) and BW CV (P = 0.008) increased with age but were not affected by treatment. Feather cleanliness was poorer in FC with low SA vs. high (P hens housed at the lower space allowance may be compromised according to some welfare assessment criteria. PMID:29050408

  1. General and simple approach for control cage and cylindrical mesopores, and thermal/hydrothermal stable frameworks.

    Science.gov (United States)

    El-Safty, Sherif A; Mizukami, Fujio; Hanaoka, Takaaki

    2005-05-19

    Highly ordered cage and cylindrical mesoporeous silica monoliths (HOM) with 2- and 3-dimensional (2D and 3D, respectively) structures, mesopore/micropore volumes, and thick-walled frameworks were successfully fabricated by instant direct templating of lyotropic phases of copolymer (EO(m)-PO(n)-EO(m)) surfactants. Large cage-like pores with uniform constriction sizes up to 10 nm and open cylindrical channel-like mesopores can be easily achieved by this simple and efficient synthesis design. Our results show that the cage-like pores could be fabricated at relatively lower copolymer concentrations used in the lyotropic phase domains at copolymer/TMOS ratios of 35 wt %. These ordered cage pore architectures underwent transition to open-cylindrical pores by increasing the copolymer concentration. High EO/PO block copolymers, in general, were crucially affected on the increase of the interior cavity sizes and on the stability of the cage mesopore characters. However, for F108 (EO(141)PO(44)EO(141)) systems, the fabrication of ordered and stable cage pore monoliths was achieved with significantly higher copolymer concentrations up to 90 wt %. Interestingly, the effective copolymer molecular nature was also observed in the ability to design various ordered mesophase geometries in large domain sizes. Our findings here show evidence that the synthetic strategy provides realistic control over a wide range of mesostructured phase geometries and their extended long-range ordering in the final replicas of the silica monolith frameworks. In addition, the HOM silica monoliths exhibited considerable structural stability against higher thermal temperature (up to 1000 degrees C) and longer hydrothermal treatment times under boiling water and steam. The remarkable structural findings of 3D frameworks, transparent monoliths, and micropores combined with large cage- and cylindrical-like mesopores are expected to find promising uses in materials chemistry.

  2. Subsidence of polyetheretherketone intervertebral cages in minimally invasive lateral retroperitoneal transpsoas lumbar interbody fusion.

    Science.gov (United States)

    Le, Tien V; Baaj, Ali A; Dakwar, Elias; Burkett, Clinton J; Murray, Gisela; Smith, Donald A; Uribe, Juan S

    2012-06-15

    A retrospective review. The objective is to evaluate subsidence related to minimally invasive lateral retroperitoneal lumbar interbody fusion by reviewing our experience with this procedure. Polyetheretherketone intervertebral cages of different lengths, widths, and heights filled with various allograft types are commonly used as spacers in lumbar fusions. Subsidence is a potential complication. To date, there are no published reports specifically addressing subsidence, because it relates to a series of patients undergoing minimally invasive lateral retroperitoneal transpsoas lumbar interbody fusion. An institutional review board-approved, retrospective review of a prospectively collected database was conducted. One hundred forty consecutive patients who underwent this procedure between L1 and L5 during a 2-year period were included. All patients had T scores of -2.5 or more. Postoperative radiographs during routine follow-ups were reviewed for subsidence, defined as any violation of the vertebral end plate. Radiographical subsidence occurred in 14.3% (20 of 140), whereas clinical subsidence occurred in 2.1%. Subsidence occurred in 8.8% (21 of 238) of levels fused. Construct length had a significant positive correlation with increasing subsidence rates. Subsidence rates decreased progressively with lower levels in the lumbar spine, but had a higher than expected rate at L4-L5. Subsidence rates of 14.1% (19 of 135) and 1.9% (2 of 103) were associated with 18-and 22-mm-wide cages, respectively. No significant trends were observed with cage lengths. Supplemental lateral plates had a higher rate of subsidence than bilateral pedicle screws. Subsidence occurred at the superior end plate 70% of the time. The use of wider intervertebral cages leads to a significantly lower rate of subsidence, but a longer cage does not necessarily offer a similar advantage. Wide cages are protective against subsidence, and the widest cages should be used whenever feasible for interbody

  3. Field cage studies and progressive evaluation of genetically-engineered mosquitoes.

    Directory of Open Access Journals (Sweden)

    Luca Facchinelli

    Full Text Available A genetically-engineered strain of the dengue mosquito vector Aedes aegypti, designated OX3604C, was evaluated in large outdoor cage trials for its potential to improve dengue prevention efforts by inducing population suppression. OX3604C is engineered with a repressible genetic construct that causes a female-specific flightless phenotype. Wild-type females that mate with homozygous OX3604C males will not produce reproductive female offspring. Weekly introductions of OX3604C males eliminated all three targeted Ae. aegypti populations after 10-20 weeks in a previous laboratory cage experiment. As part of the phased, progressive evaluation of this technology, we carried out an assessment in large outdoor field enclosures in dengue endemic southern Mexico.OX3604C males were introduced weekly into field cages containing stable target populations, initially at 10:1 ratios. Statistically significant target population decreases were detected in 4 of 5 treatment cages after 17 weeks, but none of the treatment populations were eliminated. Mating competitiveness experiments, carried out to explore the discrepancy between lab and field cage results revealed a maximum mating disadvantage of up 59.1% for OX3604C males, which accounted for a significant part of the 97% fitness cost predicted by a mathematical model to be necessary to produce the field cage results.Our results indicate that OX3604C may not be effective in large-scale releases. A strain with the same transgene that is not encumbered by a large mating disadvantage, however, could have improved prospects for dengue prevention. Insights from large outdoor cage experiments may provide an important part of the progressive, stepwise evaluation of genetically-engineered mosquitoes.

  4. Controlled Formation of Heteroleptic [Pd2(La)2(Lb)2](4+) Cages.

    Science.gov (United States)

    Preston, Dan; Barnsley, Jonathan E; Gordon, Keith C; Crowley, James D

    2016-08-24

    Metallosupramolecular architectures are beginning to be exploited for a range of applications including drug delivery, catalysis, molecular recognition, and sensing. For the most part these achievements have been made with high-symmetry metallosupramolecular architectures composed of just one type of ligand and metal ion. Recently, considerable efforts have been made to generate metallosupramolecular architectures that are made up of multiple different ligands and/or metals ions in order to obtain more complex systems with new properties. Herein we show that the addition of an electron-rich 2-amino-substituted tripyridyl ligand, 2,6-bis(pyridin-3-ylethynyl)pyridine (2A-tripy), to a solution of the [Pd2(tripy)4](4+) cage resulted in the clean generation of a heteroleptic [Pd2(tripy)2(2A-tripy)2](4+) architecture. The formation of the mixed-ligand cage [Pd2(tripy)2(2A-tripy)2](4+) was confirmed using (1)H NMR spectroscopy, diffusion-ordered spectroscopy, and rotating-frame nuclear Overhauser effect spectroscopy and high-resolution electrospray ionization mass spectrometry. Density functional theory calculations suggested the cis isomer was more stable that the trans isomer. Additionally, the calculations indicated that the heteroleptic palladium(II) cages are kinetically metastable intermediates rather than the thermodynamic product of the reaction. Competition experiments supported that finding and showed the cages are long-lived in solution at room temperature. Finally, it was shown that the addition of 2A-tripy to a range of preformed [Pd2(Ltripy)4](4+) cages cleanly generated the mixed-ligand systems. Three other systems displaying different exo and endo functionalities within the cage assembly were generated, suggesting that this method could be applied to synthesize a range of highly functionalized heteroleptic cis-[Pd2(La)2(Lb)2](4+) cages.

  5. The model of double-cage induction motor for the analysis of thermal fields in transient operations

    Directory of Open Access Journals (Sweden)

    Mróz Jan

    2017-06-01

    Full Text Available Emergency motor switch-on happens occasionally while operating a doublesquirrel- cage motor at full supply voltage with the rotor blocked (e.g., in coal mills. After releasing the blockage, the by now heated motor is started up again. However, the mechanical stress caused by the increased temperature poses considerable hazards to the squirrel-cage winding. This paper presents a double-cage induction motor model for analysis of thermal fields in transient operation. The thermal field for the rotor of a doublesquirrel- cage motor of soldered or cast structure, operating in the conditions described, has been calculated in the present paper using a thermal network method. Measurement results have been presented for the double-squirrel-cage winding temperature for a soldered cage construction in the blocked rotor state.

  6. Motion of Br2 molecules in clathrate cages. A computational study of the dynamic effects on its spectroscopic behavior.

    Science.gov (United States)

    Bernal-Uruchurtu, M I; Janda, Kenneth C; Hernández-Lamoneda, R

    2015-01-22

    This work looks into the spectroscopic behavior of bromine molecules trapped in clathrate cages combining different methodologies. We developed a semiempirical quantum mechanical model to incorporate through molecular dynamics trajectories, the effect movement of bromine molecules in clathrate cages has on its absorption spectra. A simple electrostatic model simulating the cage environment around bromine predicts a blue shift in the spectra, in good agreement with the experimental evidence.

  7. Final Report for DUSEL R&D: BetaCage: A Screener of Ultra-Low-Level Radioactive Surface Contamination

    Energy Technology Data Exchange (ETDEWEB)

    Golwala, Sunil R. [California Institute of Technology

    2013-12-20

    The eventual full-size, radiopure BetaCage will be a low-background, atmospheric-pressure neon drift chamber with unprecedented sensitivity to emitters of low-energy electrons and alpha particles. We expect that the prototype BetaCage already developed will be an excellent screener of alpha particles. Both the prototype and final BetaCage will provide new infrastructure for rare-event science.

  8. Technical Study of a Standalone Photovoltaic-Wind Energy Based Hybrid Power Supply Systems for Island Electrification in Malaysia.

    Science.gov (United States)

    Samrat, Nahidul Hoque; Ahmad, Norhafizan; Choudhury, Imtiaz Ahmed; Taha, Zahari

    2015-01-01

    Energy is one of the most important factors in the socioeconomic development of a country. In a developing country like Malaysia, the development of islands is mostly related to the availability of electric power. Power generated by renewable energy sources has recently become one of the most promising solutions for the electrification of islands and remote rural areas. But high dependency on weather conditions and the unpredictable nature of these renewable energy sources are the main drawbacks. To overcome this weakness, different green energy sources and power electronic converters need to be integrated with each other. This study presents a battery storage hybrid standalone photovoltaic-wind energy power supply system. In the proposed standalone hybrid system, a DC-DC buck-boost bidirectional converter controller is used to accumulates the surplus hybrid power in the battery bank and supplies this power to the load during the hybrid power shortage by maintaining the constant dc-link voltage. A three-phase voltage source inverter complex vector control scheme is used to control the load side voltage in terms of the voltage amplitude and frequency. Based on the simulation results obtained from MATLAB/Simulink, it has been found that the overall hybrid framework is capable of working under variable weather and load conditions.

  9. Economic and Environmental Assessment of a Renewable Stand-Alone Energy Supply System Using Multi-objective Optimization

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dohyun; Han, Seulki; Kim, Jiyong Kim [Incheon National University, Incheon (Korea, Republic of)

    2017-06-15

    This study aims to propose a new optimization-based approach for design and analysis of the stand-alone hybrid energy supply system using renewable energy sources (RES). In the energy supply system, we include multiple energy production technologies such as Photovoltaics (PV), Wind turbine, and fossil-fuel-based AC generator along with different types of energy storage and conversion technologies such as battery and inverter. We then select six different regions of Korea to represent various characteristics of different RES potentials and demand profiles. We finally designed and analyzed the optimal RES stand-alone energy supply system in the selected regions using multiobjective optimization (MOOP) technique, which includes two objective functions: the minimum cost and the minimum CO{sub 2} emission. In addition, we discussed the feasibility and expecting benefits of the systems by comparing to conventional systems of Korea. As a result, the region of the highest RES potential showed the possibility to remarkably reduce CO{sub 2} emissions compared to the conventional system. Besides, the levelized cost of electricity (LCOE) of the RES-based energy system is identified to be slightly higher than conventional energy system: 0.35 and 0.46 $/kWh, respectively. However, the total life-cycle emission of CO{sub 2} (LCECO{sub 2}) can be reduced up to 470 gCO{sub 2}/kWh from 490 gCO{sub 2}/kWh of the conventional systems.

  10. Comparison of pulp-mill-integrated hydrogen production from gasified black liquor with stand-alone production from gasified biomass

    International Nuclear Information System (INIS)

    Andersson, E.; Harvey, S.

    2007-01-01

    When gasified black liquor is used for hydrogen production, significant amounts of biomass must be imported. This paper compares two alternative options for producing hydrogen from biomass: (A) pulp-mill-integrated hydrogen production from gasified back liquor; and (B) stand-alone production of hydrogen from gasified biomass. The comparison assumes that the same amount of biomass that is imported in Alternative A is supplied to a stand-alone hydrogen production plant and that the gasified black liquor in Alternative B is used in a black liquor gasification combined cycle (BLGCC) CHP unit. The comparison is based upon equal amounts of black liquor fed to the gasifier, and identical steam and power requirements for the pulp mill. The two systems are compared on the basis of total CO 2 emission consequences, based upon different assumptions for the reference energy system that reflect different societal CO 2 emissions reduction target levels. Ambitions targets are expected to lead to a more CO 2 -lean reference energy system, in which case hydrogen production from gasified black liquor (Alternative A) is best from a CO 2 emissions' perspective, whereas with high CO 2 emissions associated with electricity production, hydrogen from gasified biomass and electricity from gasified black liquor (Alternative B) is preferable. (author)

  11. Multi-objective optimal planning of the stand-alone microgrid system based on different benefit subjects

    International Nuclear Information System (INIS)

    Guo, Li; Wang, Nan; Lu, Hai; Li, Xialin; Wang, Chengshan

    2016-01-01

    As an important means to realize the energetic complementarity and improve the efficiency of renewable resources, the stand-alone microgrid (SAMG) system gains attention increasingly, especially in islands and remote areas. In this paper, considering the interest conflict of the distribution company and the distributed generation owner, a new multi-objective optimal planning model is formulated for medium voltage SAMG. Besides, to avoid the power constraint of distributed generation (DG) once the over-limit voltage occurs, a novel two-step power dispatch control method including the voltage regulation strategy is proposed, in which the absorption of distributed power by energy storage system (ESS) and the reactive power adjustment though its power control system are used to regulate voltage. The goal of this paper is to search the Pareto-optimal front of the site and capacity of DG as well as the contract price between both parties, and thus can provide effective references for practical planning of SAMG. Considering the high cost of ESS, the investment analysis of ESS is also discussed in the paper. - Highlights: • A multi-objective planning model based on different benefit subjects is proposed. • A two-step power dispatch method including the voltage regulation is proposed. • The economical efficiency of the proposed model is analyzed. • The effective reference for the stand-alone microgrid planning is provided.

  12. Technical Study of a Standalone Photovoltaic-Wind Energy Based Hybrid Power Supply Systems for Island Electrification in Malaysia.

    Directory of Open Access Journals (Sweden)

    Nahidul Hoque Samrat

    Full Text Available Energy is one of the most important factors in the socioeconomic development of a country. In a developing country like Malaysia, the development of islands is mostly related to the availability of electric power. Power generated by renewable energy sources has recently become one of the most promising solutions for the electrification of islands and remote rural areas. But high dependency on weather conditions and the unpredictable nature of these renewable energy sources are the main drawbacks. To overcome this weakness, different green energy sources and power electronic converters need to be integrated with each other. This study presents a battery storage hybrid standalone photovoltaic-wind energy power supply system. In the proposed standalone hybrid system, a DC-DC buck-boost bidirectional converter controller is used to accumulates the surplus hybrid power in the battery bank and supplies this power to the load during the hybrid power shortage by maintaining the constant dc-link voltage. A three-phase voltage source inverter complex vector control scheme is used to control the load side voltage in terms of the voltage amplitude and frequency. Based on the simulation results obtained from MATLAB/Simulink, it has been found that the overall hybrid framework is capable of working under variable weather and load conditions.

  13. Technical Study of a Standalone Photovoltaic–Wind Energy Based Hybrid Power Supply Systems for Island Electrification in Malaysia

    Science.gov (United States)

    Samrat, Nahidul Hoque; Ahmad, Norhafizan; Choudhury, Imtiaz Ahmed; Taha, Zahari

    2015-01-01

    Energy is one of the most important factors in the socioeconomic development of a country. In a developing country like Malaysia, the development of islands is mostly related to the availability of electric power. Power generated by renewable energy sources has recently become one of the most promising solutions for the electrification of islands and remote rural areas. But high dependency on weather conditions and the unpredictable nature of these renewable energy sources are the main drawbacks. To overcome this weakness, different green energy sources and power electronic converters need to be integrated with each other. This study presents a battery storage hybrid standalone photovoltaic-wind energy power supply system. In the proposed standalone hybrid system, a DC-DC buck-boost bidirectional converter controller is used to accumulates the surplus hybrid power in the battery bank and supplies this power to the load during the hybrid power shortage by maintaining the constant dc-link voltage. A three-phase voltage source inverter complex vector control scheme is used to control the load side voltage in terms of the voltage amplitude and frequency. Based on the simulation results obtained from MATLAB/Simulink, it has been found that the overall hybrid framework is capable of working under variable weather and load conditions. PMID:26121032

  14. Feasibility Study of Standalone PV-Wind-Diesel Energy Systems for Coastal Residential Application in Pekan, Pahang

    Directory of Open Access Journals (Sweden)

    Zailan Roziah

    2017-01-01

    Full Text Available Techno economic study is feasible to optimize the usage of renewable energy components that targeting low cost of electricity generation system. The selected case study area is coastal area in Pekan, Pahang, Malaysia. The autonomous system designed in this study is hybrid standalone PV-wind-diesel energy system to fulfil a basic power demand of 20.1 kWh/day. Such power system was designed and optimized further to meet the power demand at a minimum cost of energy using energy optimization software, Hybrid Optimization Model for Electric Renewables (HOMER. The analysis focused on the operational characteristics and economics. The standalone PV-wind-diesel energy system has total net present cost about $61, 911 with cost of energy $0.66/kWh. Apparently, the generation of electricity from both wind turbine and PV can be inflated with the diesel generator. In comparison, return of investment (ROI value turned out lower for Feed in Tariff (FIT as compared to self-sustained house. Payback period also longer for FIT program that makes the selling back of electricity generated to Tenaga National Berhad (TNB is considered not favourable.

  15. SedInConnect: a stand-alone, free and open source tool for the assessment of sediment connectivity

    Science.gov (United States)

    Crema, Stefano; Cavalli, Marco

    2018-02-01

    There is a growing call, within the scientific community, for solid theoretic frameworks and usable indices/models to assess sediment connectivity. Connectivity plays a significant role in characterizing structural properties of the landscape and, when considered in combination with forcing processes (e.g., rainfall-runoff modelling), can represent a valuable analysis for an improved landscape management. In this work, the authors present the development and application of SedInConnect: a free, open source and stand-alone application for the computation of the Index of Connectivity (IC), as expressed in Cavalli et al. (2013) with the addition of specific innovative features. The tool is intended to have a wide variety of users, both from the scientific community and from the authorities involved in the environmental planning. Thanks to its open source nature, the tool can be adapted and/or integrated according to the users' requirements. Furthermore, presenting an easy-to-use interface and being a stand-alone application, the tool can help management experts in the quantitative assessment of sediment connectivity in the context of hazard and risk assessment. An application to a sample dataset and an overview on up-to-date applications of the approach and of the tool shows the development potential of such analyses. The modelled connectivity, in fact, appears suitable not only to characterize sediment dynamics at the catchment scale but also to integrate prediction models and as a tool for helping geomorphological interpretation.

  16. A Control Approach and Supplementary Controllers for a Stand-Alone System with Predominance of Wind Generation

    Directory of Open Access Journals (Sweden)

    Tiago Lukasievicz

    2018-02-01

    Full Text Available This paper proposes a control approach and supplementary controllers for the operation of a hybrid stand-alone system composed of a wind generation unit and a conventional generation unit based on synchronous generator (CGU. The proposed controllers allow the islanded or isolated operation of small power systems with predominance of wind generation. As an advantage and a paradigm shift, the DC-link voltage of the wind unit is controlled by means of a conventional synchronous generator connected to the AC grid of the system. Two supplementary controllers, added to a diesel generator (DIG and to a DC dump load (DL, are proposed to control the DC-link voltage. The wind generation unit operates in V-f control mode and the DIG operates in PQ control mode, which allows the stand-alone system to operate either in wind-diesel (WD mode or in wind-only (WO mode. The strong influence of the wind turbine speed variations in the DC-link voltage is mitigated by a low-pass filter added to the speed control loop of the wind turbine. The proposed control approach does not require the use battery bank and ultra-capacitor to control the DC-link voltage in wind generation units based on fully rated converter.

  17. John Cage y su influencia en la obra del video artista Nam June Paik

    Directory of Open Access Journals (Sweden)

    Sarriugarte Gómez, Íñigo

    2009-12-01

    Full Text Available In 1958, the Korean artist Nam June Paik (*1932; †2006 meets in Germany John Cage (*1912; †1992, avant-garde musician, who was deeply interested in the Zen Buddhism. The meeting with Cage was vital, because the North American composer will convince him to orient his career towards the artistic avant-garde, giving up his facet like classic pianist. The philosophy of Cage is refl ected in compositions like “4’ 33’’, from 1952, where the spectator doesn’t listen the sound of the piano, because this isn’t played, but he listens a silence that is interrupted by the environmental sound. There are several versions of this piece, marking the silences by means of processes at random with the “I Ching”. In this sense, the silence used by John Cage is related to the vacuity of the Zen Buddhism. Also, Paik makes use of silence in numerous works, like “1963 TV Clock”, where 24 colour television sets are manipulated, feeling at the same time the silence, interrupted again by the own momentary circumstances of the spectator. This same infl uence of the Zen Buddhism in the music of Cage is observed when argues that the music composed of melodies has the same value than the sound understood by us like noises. This aspect, among others, infl uenced to Paik, whose video images are defi ned like attributes of traditional works that don’t impress to the audience, but they suggest variable conditions. Some of his works related to Cage’s philosophy have been “Hommage à John Cage” from 1959; “Study for pianoforte” from 1960; and “Global Grove” from 1973, where Paik uses as a collage the images of his avant-garde collaborators John Cage, Allen Ginsberg and Merce Cunningham.

    En 1958, el artista coreano Nam June Paik (*1932; †2006 conoce en Alemania a John Cage (*1912; †1992, músico vanguardista, quien estaba profundamente interesado en el budismo zen. Su encuentro con Cage fue vital, ya que el compositor

  18. Octahedral [Pd6L8]12+Metallosupramolecular Cages: Synthesis, Structures and Guest-Encapsulation Studies.

    Science.gov (United States)

    Kim, Tae Y; Digal, Lori; Gardiner, Michael G; Lucas, Nigel T; Crowley, James D

    2017-10-26

    Four planar tripyridyl ligands (L tripy ), 1,3,5-tris(pyridin-3-ylethynyl)benzene 1 a, 1,3,5-tris[4-(3-pyridyl)phenyl]benzene 2 a, and the hexyloxy chain functionalized derivatives 1,3,5-tris[(3-hexyloxy-5-pyridyl)ethynyl]benzene 1 b, and 1,3,5-tris[4-(3-hexyloxy-5-pyridyl)phenyl]benzene 2 b, were synthesized and used to generate a family of [Pd 6 (L tripy ) 8 ](BF 4 ) 12 octahedral cages (L tripy =1 a, b or 2 a, b). The ligands and cages were characterized using a combination of 1 H, 13 C, and DOSY nuclear magnetic resonance (NMR) spectroscopy, high resolution electrospray mass spectrometry (HR-ESI-MS), infrared (IR) spectroscopy, elemental analysis, and in three cases, X-ray crystallography. The molecular recognition properties of the cages with neutral and anionic guests were examined, in dimethyl sulfoxide (DMSO), using NMR spectroscopy, mass spectrometry and molecular modeling. No binding was observed with simple aliphatic and aromatic guest molecules. However, anionic sulfonates were found to interact with the octahedral cages and the binding interaction was size selective. The smaller [Pd 6 (1 a, b) 8 ] 12+ cages were able to interact with three p-toluenesulfonate guest molecules while the larger [Pd 6 (2 a, b) 8 ] 12+ systems could host four of the anionic guest molecules. To probe the importance of the hydrophobic effect, a mixed water-DMSO (1:1) solvent system was used to reexamine the binding of the neutral organic guests adamantane, anthracene, pyrene and 1,8-naphthalimide within the cages. In this solvent system all the guests except adamantane were observed to bind within the cavities of the cages. NMR spectroscopy and molecular modeling indicated that the cages bind multiple copies of the individual guests (between 3-6 guest molecules per cage). © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study.

    Science.gov (United States)

    Bozkurt, Celal; Şenköylü, Alpaslan; Aktaş, Erdem; Sarıkaya, Baran; Sipahioğlu, Serkan; Gürbüz, Rıza; Timuçin, Muharrem

    2018-01-01

    Cage design and material properties play a crucial role in the long-term results, since interbody fusions using intervertebral cages have become one of the basic procedures in spinal surgery. Our aim is to design a novel Apatite-Wollastonite interbody fusion cage and evaluate its biomechanical behavior in silico in a segmental spinal model. Mechanical properties for the Apatite-Wollastonite bioceramic cages were obtained by fitting finite element results to the experimental compression behavior of a cage prototype. The prototype was made from hydroxyapatite, pseudowollastonite, and frit by sintering. The elastic modulus of the material was found to be 32 GPa. Three intact lumbar vertebral segments were modelled with the ANSYS 12.0.1 software and this model was modified to simulate a Posterior Lumbar Interbody Fusion. Four cage designs in different geometries were analyzed in silico under axial loading, flexion, extension, and lateral bending. The K2 design had the best overall biomechanical performance for the loads considered. Maximum cage stress recorded was 36.7 MPa in compression after a flexion load, which was within the biomechanical limits of the cage. Biomechanical analyses suggest that K2 bioceramic cage is an optimal design and reveals essential material properties for a stable interbody fusion.

  20. Biomechanical evaluation of immediate stability with rectangular versus cylindrical interbody cages in stabilization of the lumbar spine

    Directory of Open Access Journals (Sweden)

    Webb John K

    2002-10-01

    Full Text Available Abstract Background Recent cadaver studies show stability against axial rotation with a cylindrical cage is marginally superior to a rectangular cage. The purpose of this biomechanical study in cadaver spine was to evaluate the stability of a new rectangular titanium cage design, which has teeth similar to the threads of cylindrical cages to engage the endplates. Methods Ten motion segments (five L2-3, five L4-5 were tested. From each cadaver spine, one motion segment was fixed with a pair of cylindrical cages (BAK, Sulzer Medica and the other with paired rectangular cages (Rotafix, Corin Spinal. Each specimen was tested in an unconstrained state, after cage introduction and after additional posterior translaminar screw fixation. The range of motion (ROM in flexion-extension, lateral bending, and rotation was tested in a materials testing machine, with +/- 5 Nm cyclical load over 10 sec per cycle; data from the third cycle was captured for analysis. Results ROM in all directions was significantly reduced (p Conclusions There was no significant difference in immediate stability in any direction between the threaded cylindrical cage and the new design of the rectangular cage with endplate teeth.

  1. DNA damage in caged Gammarus fossarum amphipods: A tool for freshwater genotoxicity assessment

    Energy Technology Data Exchange (ETDEWEB)

    Lacaze, Emilie [Universite de Lyon, INRA-ENTPE, Laboratoire des Sciences de l' Environnement, rue Maurice Audin, Vaulx en Velin F-69518 (France); Cemagref, Unite de Recherche des Milieux Aquatiques, (UR MALY), 3 bis quai Chauveau, 69336 Lyon, Cedex 9 (France); Devaux, Alain [Universite de Lyon, INRA-ENTPE, Laboratoire des Sciences de l' Environnement, rue Maurice Audin, Vaulx en Velin F-69518 (France); Mons, Raphael [Cemagref, Unite de Recherche des Milieux Aquatiques, (UR MALY), 3 bis quai Chauveau, 69336 Lyon, Cedex 9 (France); Bony, Sylvie [Universite de Lyon, INRA-ENTPE, Laboratoire des Sciences de l' Environnement, rue Maurice Audin, Vaulx en Velin F-69518 (France); Garric, Jeanne [Cemagref, Unite de Recherche des Milieux Aquatiques, (UR MALY), 3 bis quai Chauveau, 69336 Lyon, Cedex 9 (France); Geffard, Alain [EA 2069 URVVC-SE, Laboratoire d' Eco-Toxicologie, UFR Sciences, Moulin de la Housse, BP 1039, 51687 Reims Cedex 2 (France); Geffard, Olivier, E-mail: olivier.geffard@cemagref.fr [Cemagref, Unite de Recherche des Milieux Aquatiques, (UR MALY), 3 bis quai Chauveau, 69336 Lyon, Cedex 9 (France)

    2011-06-15

    The aim of this study was to propose a tool for freshwater environmental genotoxicity assessment using Gammarus fossarum, a high ecologically relevant species. In a first part, gammarids were caged upstream and downstream wastewater treatment plant effluent output. The sensitivity of genotoxic responses of haemocytes, oocytes and spermatozoa was compared using the Comet assay. Spermatozoa appeared to be the most sensitive, suitable and relevant cell type for genotoxicity risk assessment. In a second part, a watershed-scale study was conducted over 2 years to evaluate the applicability of our caging procedure. The genotoxic impact of a contamination was followed, taking into account seasonal variability. DNA damage in spermatozoa exhibited low basal level and low variability in control upstream sites, providing a reliable discrimination of polluted sites. Finally, DNA damage in caged G. fossarum has been proved to be a sensitive and reproducible tool for freshwater genotoxicity assessment. - Highlights: > Two different contamination contexts: WWTP effluents and polymetallic contamination. > DNA damage in caged Gammarus fossarum is a sensitive tool for freshwater quality assessment. > Spermatozoa is the most relevant cell type for biomonitoring freshwater genotoxicity. > Combining biomarker responses with analytical chemistry provides rich ecotoxicological information. - We propose an approach to assess freshwater genotoxicity in the field based on caged Gammarus fossarum (Crustacea, amphipoda).

  2. Triangular Monometallic Cyanide Cluster Entrapped in Carbon Cage with Geometry-Dependent Molecular Magnetism.

    Science.gov (United States)

    Liu, Fupin; Gao, Cong-Li; Deng, Qingming; Zhu, Xianjun; Kostanyan, Aram; Westerström, Rasmus; Wang, Song; Tan, Yuan-Zhi; Tao, Jun; Xie, Su-Yuan; Popov, Alexey A; Greber, Thomas; Yang, Shangfeng

    2016-11-09

    Clusterfullerenes are capable of entrapping a variety of metal clusters within carbon cage, for which the entrapped metal cluster generally keeps its geometric structure (e.g., bond distance and angle) upon changing the isomeric structure of fullerene cage, and whether the properties of the entrapped metal cluster is geometry-dependent remains unclear. Herein we report an unusual triangular monometallic cluster entrapped in fullerene cage by isolating several novel terbium cyanide clusterfullerenes (TbNC@C 82 ) with different cage isomeric structures. Upon varying the isomeric structure of C 82 cage from C 2 (5) to C s (6) and to C 2v (9), the entrapped triangular TbNC cluster exhibits significant distortions as evidenced by the changes of Tb-C(N) and C-N bond distances and variation of the Tb-C(N)-N(C) angle by up to 20°, revealing that the geometric structure of the entrapped triangular TbNC cluster is variable. All three TbNC@C 82 molecules are found to be single-ion magnets, and the change of the geometric structure of TbNC cluster directly leads to the alternation of the magnetic relaxation time of the corresponding TbNC@C 82 clusterfullerene.

  3. RESULTS OF THE USE OF PEEK CAGES IN THE TREATMENT OF BASILAR INVAGINATION BY GOEL TECHNIQUE

    Directory of Open Access Journals (Sweden)

    Luís Eduardo Carelli Teixeira da Silva

    2016-03-01

    Full Text Available ABSTRACT Objective: Analysis of the use of polyetheretherketone (PEEK cages for atlantoaxial facet realignment and distraction for treatment of basilar invagination by Goel technique. Method: Retrospective descriptive statistical analysis of the neurological status, pain, presence of subsidence and bone fusion with the use of PEEK cages in 8 atlantoaxial joints of 4 patients with basilar invagination. All patients were treated with atlantoaxial facet distraction and realignment and subsequent arthrodesis C1-C2 by the technique of Goel modified by the use of PEEK cage. Results: All patients showed improvement in Nurick neurological assessment scale and Visual Analogue Scale (VAS of pain. There were no cases of subsidence, migration, or damage to the vertebral artery during the insertion of the cage. All joints evolved with bone fusion, assessed by dynamic radiographs, and computed tomography. Two patients developed neuropathic pain in dermatome of C2 and one patient had unilateral vertebral artery injury during C2 instrumentation treated with insertion of pedicle screw to control the bleeding. Conclusion: The results of the treatment of basilar invagination by the Goel technique with the use of PEEK cages shown to be effective and safe although further studies are needed to confirm this use.

  4. Small Cages with Insect Couples Provide a Simple Method for a Preliminary Assessment of Mating Disruption

    Directory of Open Access Journals (Sweden)

    Françoise Briand

    2012-01-01

    Full Text Available Mating disruption by sex pheromones is a sustainable, effective and widely used pest management scheme. A drawback of this technique is its challenging assessment of effectiveness in the field (e.g., spatial scale, pest density. The aim of this work was to facilitate the evaluation of field-deployed pheromone dispensers. We tested the suitability of small insect field cages for a pre-evaluation of the impact of sex pheromones on mating using the grape moths Eupoecilia ambiguella and Lobesia botrana, two major pests in vineyards. Cages consisted of a cubic metal frame of 35 cm sides, which was covered with a mosquito net of 1500 μm mesh size. Cages were installed in the centre of pheromone-treated and untreated vineyards. In several trials, 1 to 20 couples of grape moths per cage were released for one to three nights. The proportion of mated females was between 15 to 70% lower in pheromone-treated compared to untreated vineyards. Overall, the exposure of eight couples for one night was adequate for comparing different control schemes. Small cages may therefore provide a fast and cheap method to compare the effectiveness of pheromone dispensers under standardised semi-field conditions and may help predict the value of setting-up large-scale field trials.

  5. Leadership in Dental Hygiene Degree Completion Programs: A Pilot Study Comparing Stand-Alone Leadership Courses and Leadership-Infused Curricula.

    Science.gov (United States)

    Smith, Michelle L; Gurenlian, JoAnn R; Freudenthal, Jacqueline J; Farnsworth, Tracy J

    2016-05-01

    The aim of this study was to define the extent to which leadership and leadership skills are taught in dental hygiene degree completion programs by comparing stand-alone leadership courses/hybrid programs with programs that infuse leadership skills throughout the curricula. The study involved a mixed-methods approach using qualitative and quantitative data. Semi-structured interviews were conducted with program directors and faculty members who teach a stand-alone leadership course, a hybrid program, or leadership-infused courses in these programs. A quantitative comparison of course syllabi determined differences in the extent of leadership content and experiences between stand-alone leadership courses and leadership-infused curricula. Of the 53 U.S. dental hygiene programs that offer degree completion programs, 49 met the inclusion criteria, and 19 programs provided course syllabi. Of the program directors and faculty members who teach a stand-alone leadership course or leadership-infused curriculum, 16 participated in the interview portion of the study. The results suggested that competencies related to leadership were not clearly defined or measurable in current teaching. Reported barriers to incorporating a stand-alone leadership course included overcrowded curricula, limited qualified faculty, and lack of resources. The findings of this study provide a synopsis of leadership content and gaps in leadership education for degree completion programs. Suggested changes included defining a need for leadership competencies and providing additional resources to educators such as courses provided by the American Dental Education Association and the American Dental Hygienists' Association.

  6. The effect of space allowance and cage size on laying hens housed in furnished cages, Part II: Behavior at the feeder

    Science.gov (United States)

    Widowski, T. M; Caston, L. J; Casey-Trott, T. M; Hunniford, M. E

    2017-01-01

    Abstract Standards for feeder (a.k.a. feed trough) space allowance (SA) are based primarily on studies in conventional cages where laying hens tend to eat simultaneously, limiting feeder space. Large furnished cages (FC) offer more total space and opportunities to perform a greater variety of behaviors, which may affect feeding behavior and feeder space requirements. Our objective was to determine the effects of floor/feeder SA on behavior at the feeder. LSL-Lite hens were housed in FC equipped with a nest, perches, and a scratch mat. Hens with SA of either 520 cm2 (Low; 8.9 cm feeder space/hen) or 748 cm2 (High; 12.8 cm feeder space/hen) per bird resulted in groups of 40 vs. 28 birds in small FC (SFC) and 80 vs. 55 in large FC (LFC). Chain feeders ran at 0500, 0800, 1100, 1400, and 1700 with lights on at 0500 and off at 1900 hours. Digital recordings of FC were scanned at chain feeder onset and every 15 min for one h after (5 scans × 5 feeding times × 2 d) to count the number of birds with their head in the feeder. All occurrences of aggressive pecks and displacements during 2 continuous 30-minute observations at 0800 h and 1700 h also were counted. Mixed model repeated analyses tested the effects of SA, cage size, and time on the percent of hens feeding, and the frequency of aggressive pecks and displacements. Surprisingly, the percent of birds feeding simultaneously was similar regardless of cage size (LFC: 23.0 ± 0.9%; SFC: 24.0 ± 1.0%; P = 0.44) or SA (Low: 23.8 ± 0.9%; High: 23.3 ± 1.0%; P = 0.62). More birds were observed feeding at 1700 h (35.3 ± 0.1%) than any at other time (P < 0.001). Feeder use differed by cage area (nest, middle, or scratch) over the d (P < 0.001). The frequency of aggressive pecks was low overall and not affected by SA or cage size. Frequency of displacements was also low but greater at Low SA (P = 0.001). There was little evidence of feeder competition at the Low SA in this study. PMID:29050409

  7. Sulfur radicals embedded in various cages of ultramarine analogs prepared from zeolites

    International Nuclear Information System (INIS)

    Kowalak, Stanislaw; Jankowska, Aldona; Zeidler, Sebastian; Wieckowski, Andrzej B.

    2007-01-01

    The colored (greenish) products analogous to ultramarine obtained from zeolite A, cancrinite and erionite by means of high-temperature (500-800 deg. C) treatment of zeolites mixed with elemental sulfur and alkalis can maintain the original structure of the parent zeolite under certain preparation conditions. The ESR spectra of samples recorded at room temperature always indicate the presence of radicals · S 3 - (the blue chromophore). The spectra of samples prepared from zeolites recorded at 77 K exhibit additional signals that could be assigned to the yellow chromophore (the radical · S 2 - ) encapsulated inside the β or ε-cages. It is remarkable that in the case of products with preserved cancrinite structure, where the · S 2 - radicals are encapsulated inside the ε-cages, the above signals are visible already at room temperature. It may result from retarded mobility of these species in small cancrinite cages. - Graphical abstract: Structures of SOD, LTA, cancrinite and erionite

  8. Design Concepts of Polycarbonate-Based Intervertebral Lumbar Cages: Finite Element Analysis and Compression Testing

    Directory of Open Access Journals (Sweden)

    J. Obedt Figueroa-Cavazos

    2016-01-01

    Full Text Available This work explores the viability of 3D printed intervertebral lumbar cages based on biocompatible polycarbonate (PC-ISO® material. Several design concepts are proposed for the generation of patient-specific intervertebral lumbar cages. The 3D printed material achieved compressive yield strength of 55 MPa under a specific combination of manufacturing parameters. The literature recommends a reference load of 4,000 N for design of intervertebral lumbar cages. Under compression testing conditions, the proposed design concepts withstand between 7,500 and 10,000 N of load before showing yielding. Although some stress concentration regions were found during analysis, the overall viability of the proposed design concepts was validated.

  9. Anterior cervical discectomy with or without fusion with ray titanium cage: a prospective randomized clinical study

    DEFF Research Database (Denmark)

    Hauerberg, J.; Kosteljanetz, M.; Bøge-Rasmussen, Torben

    2008-01-01

    STUDY DESIGN: A prospective randomized clinical study. OBJECTIVE: To compare 2 surgical methods in the treatment of cervical radiculopathy caused by hard or soft disc herniation; namely, simple discectomy versus discectomy with an additional interbody fusion with a Ray titanium cage. SUMMARY...... of the nervous elements have been performed. To date, no randomized studies have compared simple discectomy with discectomy followed by an interbody fusion with a titanium cage. METHODS: Eighty-six patients with symptoms of nerve root compression at 1 level were randomly allocated to either discectomy followed...... by fusion with a Ray titanium cage (40 patients) or to discectomy alone (46 patients). Clinical and radiologic follow-up was performed 3, 12, and 24 months after surgery. RESULTS: There was no statistically significant difference between the 2 groups concerning self-reported satisfaction or severity of pain...

  10. The use of porous tantalum cages in the treatment of unremitting spondylodiscitis: a case report

    Directory of Open Access Journals (Sweden)

    Samo Karel Fokter

    2018-03-01

    Full Text Available Background: Unsuccessful medical treatment of pyogenic multifocal spondylodiscitis including signs of sepsis and unremitting pain is challenging. The aim of our report was to present a case of multilevel spondylodiscitis successfully treated by posterior lumbar interbody fusion using porous tantalum cages. Case presentation: A 59-year-old male was diagnosed with spondylodiscitis at T8-T9 level. Although treated with antibiotics, the patient again presented with worsening of systemic signs of infection and back pain. Contrast-enhanced magnetic resonance imaging studies revealed spondylodiscitis at L1 to S1 level. Posterior lumbar interbody bone fusion with tantalum cages from L1 to S1 was performed. The inflammation rapidly subsided. Computer tomography studies showed a stable construct at 24 months. Conclusion: Porous tantalum cages used in combination with transpedicular fixation seem to be a sound alternative to interbody devices made from other materials when treating spondylodiscitis cases without definite osseous destruction.

  11. Cytotoxic and anti-HIV-1 caged xanthones from the resin and fruits of Garcinia hanburyi.

    Science.gov (United States)

    Reutrakul, Vichai; Anantachoke, Natthinee; Pohmakotr, Manat; Jaipetch, Thaworn; Sophasan, Samaisukh; Yoosook, Chalobon; Kasisit, Jittra; Napaswat, Chanita; Santisuk, Thawatchai; Tuchinda, Patoomratana

    2007-01-01

    Three new caged xanthones, 7-methoxydesoxymorellin (1), 2-isoprenylforbesione (2) and 8,8a-epoxymorellic acid (3), together with nine known caged xanthones were isolated from the EtOAc extracts of resin and fruits of Garcinia hanburyi. The structures were determined by spectroscopic methods. Most of the isolated compounds showed significant cytotoxicities against a panel of mammalian cancer cell lines. Compound 3, together with the known compounds desoxymorellin, morellic acid, gambogic acid, hanburin, forbesione and dihydroisomorellin, exhibited anti-HIV-1 activity in the reverse transcriptase (RT) assay while the known compounds desoxygambogenin and dihydroisomorellin were found moderately active in the syncytium assay. This work represents the first report on the anti-HIV-1 activities of caged xanthones.

  12. Mediterranean fruit fly: interference of oviposition by radiation-sterilized females in field cages

    International Nuclear Information System (INIS)

    McInnis, D.O.; Wong, T.T.Y.

    1990-01-01

    In experiments between April and September 1984, the behaviour of nonirradiated and radiation-sterilized laboratory-adapted adults of the tephritid Ceratitis capitata was observed on apples hung on guava trees in outdoor cages in Hawaii. The numbers of nonirradiated females observed resting on fruit were reduced several times by the presence of irradiated females, either alone or with irradiated males, but not by irradiated males alone. Similarly, the number of nonirradiated females observed ovipositing and the duration of oviposition was reduced by the presence of irradiated females. In control cages (all nonirradiated flies), the duration of oviposition by females averaged 255.9±15.0 s on fruit, while most of nonirradiated and irradiated females in the mixed (treatment) cage averaged 157±19.8 s and 77.5±7.5 s on fruit, resp. Irradiated females behaved skittishly on fruit and frequently engaged in physical encounters with other flies

  13. EFFICACY OF CAGE PLACEMENT WITHOUT PLATE IN PATIENTS WITH CERVICAL MYELOPATHY WITH SINGLE-LEVEL AFFECTION

    Directory of Open Access Journals (Sweden)

    CARLOS ALBERTO ZUÑIGA-MAZÓN

    Full Text Available ABSTRACT Objective: To determine the efficacy of PEEK (Poly-ether-ether-ketone cage without plate for the treatment of single-level cervical spondylosis. Methods: Ten patients with cervical myelopathy data, with a single-level root condition, seen at the outpatient clinic of the Neurosurgery Service, operated in 2016, mean age 53 years, 6 (60% female, 4 (40% obese, 3 (30% smokers. The Cloward technique was used by anterior approach, discectomy, and PEEK cage placement. Results: At six months of surgery, 100% of the patients had increased intervertebral space, with a 100% reduction in osteophytes; only one patient had dysphagia, no patient had lesion of the adjacent segment and 10% had persistent root pathology. Cervical lordosis was observed in 90% of the patients and arthrodesis in 100% of the cases. Conclusions: Anterior approach arthrodesis using PEEK cage without cervical plate is effective as a treatment of cervical myelopathy in a single level.

  14. OE CAI: COMPUTER-ASSISTED INSTRUCTION OF OLD ENGLISH

    Directory of Open Access Journals (Sweden)

    Alejandro Alcaraz Sintes

    2002-06-01

    Full Text Available This article offer a general but thorougli survey of Computer Assisted lnstruction as applied to the Old English language íkoni the work of the late 80's pioneers to December 2001. It enibraces all the different facets of the question: stand-alone and web-based applications, Internet sites. CD-ROMs, grammars, dictioriaries, general courses, reading software, extralinguistic material, exercises, handouts, audio files ... Each instruction itee whether it be a website, a java exercise, an online course or an electronic book- is reviewed and URLs are provided in Sootiiotes. These reviews are accompanied all throughout by the pertinent theoretical background and practical advice.

  15. Analysis of Heavy Metal Content (Pb) on Waters and Fish at The Floating Cages BPPP Ambon

    Science.gov (United States)

    Wattimena, Rachel L.; Selanno, Debby A. J.; Tuhumury, Semuel F.; Tuahatu, Juliana W.

    2018-02-01

    Coastal waters play important roles due to highly in natural resources and developing of environmental services. However, there are highly intensity of natural resources utilization, environment and settlement. Consequently, environment and natural resources would be degraded such as in the Ambon Bay. One of the potency at the Ambon Bay is mariculture area namely the floating cages (KJA) which belongs to Fisheries education and training (BPPP) Ambon. The research aimed to analyze physical-chemical of waters (temperature, pH, salinity and current speed), to analyze heavy metal concentration (Pb) on water and fish from floating cages (KJA) and to analyze waters pollution status at KJA BPPP Ambon. The average salinity of each floating cage ranged from 30.09 - 30.34°C, pH ranged from 8.03 - 8.44, salinity ranged from 31.36 - 33.34 PSU, and current speed at spring tide ranged from 0.5 - 55.8 Cm/sec while neap tide ranged from 0.1 - 9.8 Cm/sec. Heavy metal concentration (Pb) on waters was below the standard for waters quality and the average concentration was 0.002 mg/l. Whilst, the heavy metal concentration (Pb) on fishes was below standard for floating cages (floating cages 2-6) which was 0.05 and 0.17mg/l. Otherwise, floating cage 1 had been above maximum standard for fish food and its processing following SNI 7387:2009 (0.3mg/l) which was 0.31 mg/l. The status of waters pollution at KJA BPPP Ambon belonged to C class and could be categorized as moderate based on standard for waters quality issued by State Ministerial Decree for the Environment No. 51 Year 2004.

  16. Specific Internalisation of Gold Nanoparticles into Engineered Porous Protein Cages via Affinity Binding

    Science.gov (United States)

    Peng, Tao; Free, Paul; Fernig, David G.; Lim, Sierin; Tomczak, Nikodem

    2016-01-01

    Porous protein cages are supramolecular protein self-assemblies presenting pores that allow the access of surrounding molecules and ions into their core in order to store and transport them in biological environments. Protein cages’ pores are attractive channels for the internalisation of inorganic nanoparticles and an alternative for the preparation of hybrid bioinspired nanoparticles. However, strategies based on nanoparticle transport through the pores are largely unexplored, due to the difficulty of tailoring nanoparticles that have diameters commensurate with the pores size and simultaneously displaying specific affinity to the cages’ core and low non-specific binding to the cages’ outer surface. We evaluated the specific internalisation of single small gold nanoparticles, 3.9 nm in diameter, into porous protein cages via affinity binding. The E2 protein cage derived from the Geobacillus stearothermophilus presents 12 pores, 6 nm in diameter, and an empty core of 13 nm in diameter. We engineered the E2 protein by site-directed mutagenesis with oligohistidine sequences exposing them into the cage’s core. Dynamic light scattering and electron microscopy analysis show that the structures of E2 protein cages mutated with bis- or penta-histidine sequences are well conserved. The surface of the gold nanoparticles was passivated with a self-assembled monolayer made of a mixture of short peptidols and thiolated alkane ethylene glycol ligands. Such monolayers are found to provide thin coatings preventing non-specific binding to proteins. Further functionalisation of the peptide coated gold nanoparticles with Ni2+ nitrilotriacetic moieties enabled the specific binding to oligohistidine tagged cages. The internalisation via affinity binding was evaluated by electron microscopy analysis. From the various mutations tested, only the penta-histidine mutated E2 protein cage showed repeatable and stable internalisation. The present work overcomes the limitations of

  17. Multifunctional ferritin cage nanostructures for fluorescence and MR imaging of tumor cells

    Science.gov (United States)

    Li, Ke; Zhang, Zhi-Ping; Luo, Ming; Yu, Xiang; Han, Yu; Wei, Hong-Ping; Cui, Zong-Qiang; Zhang, Xian-En

    2011-12-01

    Bionanoparticles and nanostructures have attracted increasing interest as versatile and promising tools in many applications including biosensing and bioimaging. In this study, to image and detect tumor cells, ferritin cage-based multifunctional hybrid nanostructures were constructed that: (i) displayed both the green fluorescent protein and an Arg-Gly-Asp peptide on the exterior surface of the ferritin cages; and (ii) incorporated ferrimagnetic iron oxide nanoparticles into the ferritin interior cavity. The overall architecture of ferritin cages did not change after being integrated with fusion proteins and ferrimagnetic iron oxide nanoparticles. These multifunctional nanostructures were successfully used as a fluorescent imaging probe and an MRI contrast agent for specifically probing and imaging αvβ3 integrin upregulated tumor cells. The work provides a promising strategy for tumor cell detection by simultaneous fluorescence and MR imaging.Bionanoparticles and nanostructures have attracted increasing interest as versatile and promising tools in many applications including biosensing and bioimaging. In this study, to image and detect tumor cells, ferritin cage-based multifunctional hybrid nanostructures were constructed that: (i) displayed both the green fluorescent protein and an Arg-Gly-Asp peptide on the exterior surface of the ferritin cages; and (ii) incorporated ferrimagnetic iron oxide nanoparticles into the ferritin interior cavity. The overall architecture of ferritin cages did not change after being integrated with fusion proteins and ferrimagnetic iron oxide nanoparticles. These multifunctional nanostructures were successfully used as a fluorescent imaging probe and an MRI contrast agent for specifically probing and imaging αvβ3 integrin upregulated tumor cells. The work provides a promising strategy for tumor cell detection by simultaneous fluorescence and MR imaging. Electronic supplementary information (ESI) available. See DOI: 10.1039/c1nr11132

  18. The Correlation Between Cage Subsidence, Bone Mineral Density, and Clinical Results in Posterior Lumbar Interbody Fusion.

    Science.gov (United States)

    Oh, Kyu Won; Lee, Jae Hyup; Lee, Ji-Ho; Lee, Do-Yoon; Shim, Hee Jong

    2017-07-01

    A retrospective review of prospectively collected radiographic and clinical data. This study aims to investigate the relationship between cage subsidence and bone mineral density (BMD), and to reveal the clinical implications of cage subsidence. Posterior lumbar interbody fusion (PLIF) has become one of the standard treatment modality for lumbar degenerative disease. However, cage subsidence might result in recurrent foraminal stenosis and deteriorate the clinical results. Furthermore, numbers of osteoporosis patients who underwent PLIF are increasing. Therefore, the information on the correlations between cage subsidence, BMD, and clinical results will be of great significance. A total 139 segments was included in this retrospective study. We examined functional rating index (Visual Analogue Scale for pain, Oswestry Disability Index, Short Form-36 score) preoperatively, and investigated their changes after postoperative 1 year. Correlation between cage subsidence and clinical scores was investigated. Plain anteroposterior and lateral radiograph were taken preoperatively and postoperatively and during follow-up. Preoperative BMD and subsidence measured by postoperative 1 year 3-dimensional computed tomography were achieved and their correlation was assessed. All postoperative clinical scores improved significantly compared with preoperative ones (pain Visual Analogue Scale: 7.34-2.89, Oswestry Disability Index: 25.34-15.86, Short Form-36: 26.45-16.46, all Psubsidence (r=-0.285, Psubsidence (>3 mm) compared with the segments in which T score were higher than -3.0 (P=0.012), and its odds ratio was 8.44. Subsidence had no significant correlation with all clinical scores. This study revealed that cage subsidence is relevant to BMD. However, it was demonstrated that subsidence is not related to the clinical deterioration. Therefore, PLIF procedure which is conducted carefully can be a good surgical option to treat lumbar degenerative disease for osteoporotic patients.

  19. Depopulation of Caged Layer Hens with a Compressed Air Foam System

    Directory of Open Access Journals (Sweden)

    Shailesh Gurung

    2018-01-01

    Full Text Available During the 2014–2015 US highly pathogenic avian influenza (HPAI outbreak, 50.4 million commercial layers and turkeys were affected, resulting in economic losses of $3.3 billion. Rapid depopulation of infected poultry is vital to contain and eradicate reportable diseases like HPAI. The hypothesis of the experiment was that a compressed air foam (CAF system may be used as an alternative to carbon dioxide (CO2 inhalation for depopulating caged layer hens. The objective of this study was to evaluate corticosterone (CORT and time to cessation of movement (COM of hens subjected to CAF, CO2 inhalation, and negative control (NEG treatments. In Experiment 1, two independent trials were conducted using young and spent hens. Experiment 1 consisted of five treatments: NEG, CO2 added to a chamber, a CO2 pre-charged chamber, CAF in cages, and CAF in a chamber. In Experiment 2, only spent hens were randomly assigned to three treatments: CAF in cages, CO2 added to a chamber, and aspirated foam. Serum CORT levels of young hens were not significantly different among the CAF in cages, CAF in a chamber, NEG control, and CO2 inhalation treatments. However, spent hens subjected to the CAF in a chamber had significantly higher CORT levels than birds in the rest of the treatments. Times to COM of spent hens subjected to CAF in cages and aspirated foam were significantly greater than of birds exposed to the CO2 in a chamber treatment. These data suggest that applying CAF in cages is a viable alternative for layer hen depopulation during a reportable disease outbreak.

  20. Analysis of Heavy Metal Content (Pb on Waters and Fish at The Floating Cages BPPP Ambon

    Directory of Open Access Journals (Sweden)

    Wattimena Rachel L.

    2018-01-01

    Full Text Available Coastal waters play important roles due to highly in natural resources and developing of environmental services. However, there are highly intensity of natural resources utilization, environment and settlement. Consequently, environment and natural resources would be degraded such as in the Ambon Bay. One of the potency at the Ambon Bay is mariculture area namely the floating cages (KJA which belongs to Fisheries education and training (BPPP Ambon. The research aimed to analyze physical-chemical of waters (temperature, pH, salinity and current speed, to analyze heavy metal concentration (Pb on water and fish from floating cages (KJA and to analyze waters pollution status at KJA BPPP Ambon. The average salinity of each floating cage ranged from 30.09 - 30.34°C, pH ranged from 8.03 − 8.44, salinity ranged from 31.36 − 33.34 PSU, and current speed at spring tide ranged from 0.5 – 55.8 Cm/sec while neap tide ranged from 0.1 – 9.8 Cm/sec. Heavy metal concentration (Pb on waters was below the standard for waters quality and the average concentration was 0.002 mg/l. Whilst, the heavy metal concentration (Pb on fishes was below standard for floating cages (floating cages 2-6 which was 0.05 and 0.17mg/l. Otherwise, floating cage 1 had been above maximum standard for fish food and its processing following SNI 7387:2009 (0.3mg/l which was 0.31 mg/l. The status of waters pollution at KJA BPPP Ambon belonged to C class and could be categorized as moderate based on standard for waters quality issued by State Ministerial Decree for the Environment No. 51 Year 2004.

  1. Depopulation of Caged Layer Hens with a Compressed Air Foam System.

    Science.gov (United States)

    Gurung, Shailesh; Hoffman, John; Stringfellow, Kendre; Abi-Ghanem, Daad; Zhao, Dan; Caldwell, David; Lee, Jason; Styles, Darrel; Berghman, Luc; Byrd, James; Farnell, Yuhua; Archer, Gregory; Farnell, Morgan

    2018-01-11

    During the 2014-2015 US highly pathogenic avian influenza (HPAI) outbreak, 50.4 million commercial layers and turkeys were affected, resulting in economic losses of $3.3 billion. Rapid depopulation of infected poultry is vital to contain and eradicate reportable diseases like HPAI. The hypothesis of the experiment was that a compressed air foam (CAF) system may be used as an alternative to carbon dioxide (CO₂) inhalation for depopulating caged layer hens. The objective of this study was to evaluate corticosterone (CORT) and time to cessation of movement (COM) of hens subjected to CAF, CO₂ inhalation, and negative control (NEG) treatments. In Experiment 1, two independent trials were conducted using young and spent hens. Experiment 1 consisted of five treatments: NEG, CO₂ added to a chamber, a CO₂ pre-charged chamber, CAF in cages, and CAF in a chamber. In Experiment 2, only spent hens were randomly assigned to three treatments: CAF in cages, CO₂ added to a chamber, and aspirated foam. Serum CORT levels of young hens were not significantly different among the CAF in cages, CAF in a chamber, NEG control, and CO₂ inhalation treatments. However, spent hens subjected to the CAF in a chamber had significantly higher CORT levels than birds in the rest of the treatments. Times to COM of spent hens subjected to CAF in cages and aspirated foam were significantly greater than of birds exposed to the CO₂ in a chamber treatment. These data suggest that applying CAF in cages is a viable alternative for layer hen depopulation during a reportable disease outbreak.

  2. Ni adsorption on Al12P12 nano-cage: A DFT study

    International Nuclear Information System (INIS)

    Rad, Ali Shokuhi; Ayub, Khurshid

    2016-01-01

    Density functional theory (DFT) calculations have been performed to evaluate the geometries and electronic properties of nickel decorated aluminum phosphide (AlP) nano-cages. At the lowest coverage of our system (one Ni per one Al 12 P 12 ), four adsorption sites (P 1 −P 4 ) of Ni on AlP nano-cage are studied. Band structures, binding energies, total density of states, natural bond orbital (NBO) charges, and electron density differences of Ni-adsorbed Al 12 P 12 nano-cages are studied for each adsorption site. We found that three orientations (P 1 , P 2 , and P 3 ) show electron transfer from the Ni to Al 12 P 12 whereas one orientation (P 4 ) has reverse direction of electron transfer. The adsorption energies of Ni on AlP nano-cage are −136.7, −108.5, −102.7, and −99.4 kcal mol −1 for P4, P3, P1 and P2, respectively. Formation of new Al−Ni and P−Ni bonds is observed concomitant with the dissociation of some Al−P bonds of the nano-cage. - Highlights: • There are four adsorption sites (P 1 , P 2 , P 3 , and P 4 ) on Al 12 P 12 nano-cage for Ni adsorption. • Direction of charge transfer for P 1 , P 2 , and P 3 are from the Ni to Al 12 P 12 while reverse direction is found for P 4 . • The order of Ni adsorption on Al 12 P 12 is: P4> P3> P1 >P2. • Dissociation of some Al−P bonds of the Al 12 P 12 and formation of new Al−Ni and P−Ni bonds upon adsorption of Ni.

  3. Interacting Stochastic Processes: From Viciousness to Caging to Force Chains

    Science.gov (United States)

    Xu, Shiliyang

    This thesis documents a quest to develop and study several novel interacting stochastic processes. As for the first example, we generalize a system of vicious random walkers in which the only interaction between any two random walkers is that when they intersect, both walkers are annihilated. We define a system of N vicious accelerating walkers with each walker undergoing random acceleration and compute the survival probability distribution for this system. We also define and study a system of N vicious Levy flights in which any two Levy flights crossing one another annihilate each other. The average mean-squared displacement of a Levy flight is not proportional to time, but scales with what is known as the Levy index divided by two. In both cases, vicious accelerating walkers and vicious Levy flights, we are motivated by ultimately generalizing our understanding of Gaussian random matrices via non-Markovian and non-Gaussian extensions respectively. Moreover, inspired by recent experiments on periodically sheared colloids at low densities, we define and investigate several new contact processes, or interacting stochastic processes, with conserved particle number and three-or-more-body interactions. We do so to characterize the periodically sheared colloidal system at higher densities. We find two new dynamical phase transitions between an active phase, where some fraction of the colloids are always being displaced from their position at the beginning and end of each shear cycle, and an inactive phase in which all colloids return to their initial positions at the end of each shear cycle. One of the transitions is discontinuous, while the second, which is due to a caging, or crowding, effect at high densities, appears to be continuous and in a new universality from what is known as conserved directed percolation. The latter transition may have implications for the onset of glassiness in dense, particulate systems. In addition, this thesis also includes analysis of

  4. Metal ion cage complexes as imaging agents for cancer cells

    International Nuclear Information System (INIS)

    Di Bartolo, N.; Smith, S.; Sargeson, A.

    2000-01-01

    Full text: Cage ligands are very attractive for use in radiolabelling antibodies. Their synthesis is based around Co(III) octahedral co-ordination chemistry and they may be easily derivatised for attachment to antibodies. They are known to form kinetically inert metal complexes. Copper-64 (t 1/2 = 12.7 h) has been identified as having potential value in diagnostic and therapeutic application. Its positron annihilation radiation is useful for PET imaging, while its beta (E max 578 keV, 37.2 %) emissions may also be suitable for therapy. In the current study, the new hexa-aza-cryptand, 1 -N-(4-amino-benzyl)-3,6,10,13,16,19-hexaaza-bicyclo[6.6.6]eicosane- 1,8-diamine, or SarAr, has been synthesised specifically for radiolabelling antibodies with 64 Cu and a kit formulation has been produced. The resulting radiolabelled immunoconjugate ( 64 Cu-SarArB-72.3) was injected into nude mice bearing LS174t colorectal carcinoma. Clearance of 64 CuSarAr-B72.3 from the liver and kidneys was typical of a whole IgG antibody. Tumour localisation was comparable to similar radiolabelled immunoconjugates (38± 5 % ID/g at 48 hours). Biodistribution studies of 123 I- and 111 In- radiolabelled B72.3 were conducted in the same animal model. MIRDOSE 3 was used to compare target to non-target dose of their analogous therapeutic counterparts ( 90 Y and 131 I respectively) with 64 Cu-SarAr-B72.3. Total body dose for 64 Cu-SarAr-B72.3 was significantly lower (0.09 rad/mCi) than analogous products ( 131 I-B72.3, 2.64 rad/mCi; 90 Y- B72.3, 2.387 rad/mCi) while still providing enough dose to small tumours to be potentially therapeutic. In order to assess therapeutic effect of 64 Cu, a biological study was conducted over a 12 month period. Nude mice bearing tumours between 3.5 - 5.5 mm in length were injected with various doses (0, 10, 20, 30, 40 MBq) of 64 Cu-SarAr-B72.3. Animals were regularly monitored for tumour size, animal mass, behavioural and physical abnormalities (e.g. movement / gait

  5. Effects of perch on feed consumption and behaviour of caged laying hens

    OpenAIRE

    E. VALKONEN; R. RINNE; J. VALAJA

    2008-01-01

    This experiment studied the effects of perches in furnished cages on behaviour and feed consumption of laying hens. The study used 352 Lohmann Selected Leghorn (LSL) hens. The hens were housed at 16 weeks of age in furnished cages in groups of 8 birds. The experiment lasted for 205 days. The treatments were: perches present from 16 weeks of age (P16), perches present from 19 weeks of age (P19), and no perches present (NP). Feed consumption and egg production were measured over the pre-laying ...

  6. Diffusion Monte Carlo characterization of a methane molecule in a (H2O)20 dodecahedral cage

    Science.gov (United States)

    Jordan, Kenneth; Deible, Michael

    2014-03-01

    The diffusion Monte Carlo method is used to investigate the interaction of a water molecule with a dodecahedral (H2O)20 cage as found in the methane hydrate crystal. The DMC value of the interaction energy between the methane molecule and the cage are compared with the results of MP2 and symmetry-adapted perturbation theory (SAPT) calculations. In addition, the net interaction energy is decomposed into two- and three-, and n >= four-body contributions. The two- and three-body contributions are further analyzed in terms of SAPT calculations. An award of computer time was provided by the Innovative and Novel Computational Impact on Theory and Experiment (INCITE) program.

  7. The Design and its Verification of the Double Rotor Double Cage Induction Motor

    Science.gov (United States)

    Sinha, Sumita; Deb, Nirmal K.; Biswas, Sujit K.

    2017-02-01

    The concept of a double rotor motor presented earlier and its equivalent circuit has been developed, showing a non-linear parameter content. The two rotors (which are recommended to be double cage type for development of high starting torque) can run with equal or unequal speed independently, depending on their individual loading. This paper presents the elaborate design procedure, step-by-step, for the double rotor double cage motor and verifies the designed data with that obtained from three separate tests (compared to two for conventional motor) on a prototype, such that optimum performance can be obtained from the motor.

  8. Calculation of the environmental capacity of cooling ponds for cage fish farming

    Directory of Open Access Journals (Sweden)

    N. Starco

    2016-12-01

    Full Text Available Purpose. The determination of a maximum annual amount of fish reared in cagesm which does not result in the deterioration of the ecological state of water cooling ponds of the Zmiev Thermal Power Plant and Kursk Nuclear Power Plant series Ι and ΙΙ. Methodology. The specific (per 1 ton of farmed fish nutrient intake necessary for calculations was determined according to the data of own studies. For this purpose, we perfrormed the determination of the input of suspended solids into cooling ponds from cage lines. The calculation of mean fish weight increase during the period of trap exposition bsed on fish farm data allowed calculating the specific input of suspended solids from cages. The effect of artificial feeds and a mixture of feed resideus and fish of fishes collected under cages on water quality were evaluated in the condoitins of laboratory experiments. The effect of fish metabolites on water quality was taken into account according to literature data. Findings. In the specific conditions of the investigated cooling ponds, the environmentally allowable concentrations of biogenic elements are established based on the mineral nitrogen content. With the mean volume of the Zmiev Thermal Power Plant of 40.5 million m3, the total amount of mineral nitrogen, which can be introduced with cage aquaculture residues, is 21.87 tons. When rearing one ton of fish in cages, 91.3 kg of mineral nitrogen get into the cooling pond. Thus, the environmental capacity of the Zmiev Thermal Power Plant cooling pond for cage fish farming is 281.7 tons. Accordingly, the allowable amounts of the production of cage fish farming for the Kursk NPP taking into account N content of 0.406 mgN/dm3 and volume of the cooling pond is 625.5 tons. Originality. For the first time, we calculated the ecological capacity of cooling ponds of the Zmiev TPP and Kursk NPP, series I–II. Practical value. Application of the results presented in the paper will allow creating and

  9. Growth and stress of dourado cultivated in cages at different stocking densities

    Directory of Open Access Journals (Sweden)

    Neiva Braun

    2013-08-01

    Full Text Available The objective of this work was to evaluate the growth and the stress levels of juvenile dourado (Salminus brasiliensis cultivated in cages. Fish stocked at densities of 15 (D15 and 30 (D30 fish per square meter were evaluated in a completely randomized design with three replicates. Fish were fed twice a day with extruded ration (42% crude protein. Density influenced only biomass and daily food intake, and glucose and lactate concentrations increased over time. D15 and D30 did not influence the growth of dourado. However, the increase of glucose and lactate levels over time indicates that cultivation in cages is a stressful condition for this species.

  10. PRODUCTIVITY OF LAYERS AND EGG QUALITY IN FREE RANGE AND CAGE SYSTEM OF HOUSING

    OpenAIRE

    Đ. Senčić; Danijela Butko

    2006-01-01

    The research was conducted with two groups of Lohmann Brown hybrid layers. Production of eggs lasted for 52 weeks. A control group of layers was kept in the conventional housing system, that is, in cages, while experimental group was kept in the free range system. Layers from the free range system, compared to those kept in cages, laid fewer eggs, (266:295), they consumed more feed on daily basis (129 g : 115 g), more feed per kilogram of egg weight (2.83 kg : 2.35 kg), they had higher mor...

  11. Thermal Degradation Mechanism of a Thermostable Polyester Stabilized with an Open-Cage Oligomeric Silsesquioxane

    Directory of Open Access Journals (Sweden)

    Yolanda Bautista

    2017-12-01

    Full Text Available A polyester composite was prepared through the polymerization of an unsaturated ester resin with styrene and an open-cage oligomeric silsesquioxane with methacrylate groups. The effect of the open-cage oligomeric silsesquioxane on the thermal stability of the thermostable polyester was studied using both thermogravimetric analysis and differential thermal analysis. The results showed that the methacryl oligomeric silsesquioxane improved the thermal stability of the polyester. The decomposition mechanism of the polyester/oligomer silsesquioxane composite was proposed by Fourier transform infrared spectroscopy (FTIR analysis of the volatiles.

  12. Thermal Degradation Mechanism of a Thermostable Polyester Stabilized with an Open-Cage Oligomeric Silsesquioxane

    Science.gov (United States)

    Gozalbo, Ana; Mestre, Sergio; Sanz, Vicente

    2017-01-01

    A polyester composite was prepared through the polymerization of an unsaturated ester resin with styrene and an open-cage oligomeric silsesquioxane with methacrylate groups. The effect of the open-cage oligomeric silsesquioxane on the thermal stability of the thermostable polyester was studied using both thermogravimetric analysis and differential thermal analysis. The results showed that the methacryl oligomeric silsesquioxane improved the thermal stability of the polyester. The decomposition mechanism of the polyester/oligomer silsesquioxane composite was proposed by Fourier transform infrared spectroscopy (FTIR) analysis of the volatiles. PMID:29295542

  13. A lightweight field cage for a large TPC prototype for the ILC

    International Nuclear Information System (INIS)

    Behnke, Ties; Dehmelt, Klaus; Diener, Ralf; Hallermann, Lea; Matsuda, Takeshi; Prahl, Volker; Schade, Peter

    2010-06-01

    We have developed and constructed the field cage of a prototype Time Projection Chamber for research and development studies for a detector at the International Linear Collider. This prototype has an inner diameter of 72 cm and a length of 61 cm. The design of the field cage wall was optimized for a low material budget of 1.21% of a radiation length and a drift field homogeneity of ΔE/E -4 . Since November 2008 the prototype has been part of a comprehensive test beam setup at DESY and used as a test chamber for the development of Micro Pattern Gas Detector based readout devices. (orig.)

  14. The Effect of Cage Space on Behavior and Reproduction in Crl:CD1(Icr and C57BL/6NCrl Laboratory Mice.

    Directory of Open Access Journals (Sweden)

    Brianna N Gaskill

    Full Text Available Recommendations for the amount of cage space required for female mice with litters were first made in the 2011 Guide for the Care and Use of Laboratory Animals. We hypothesized that if a difference in mouse behavior and reproduction exists within the limits of commercially available caging, this difference would be detected between the smallest and largest cages. C57BL/6NCrl and Crl:CD1(Icr breeding mice were randomly assigned to a cage treatment: LP 18790 (226 cm2; A RC1 (305 cm2; A N10 (432 cm2; T 1291 (800 cm2 and a breeding configuration: single (male removed after birth; pair (1 male + 1 female; or trio (1 male + 2 females in a factorial design for 12 weeks. All cages received 8-10 g of nesting material and nests were scored weekly. Pups were weaned between post-natal day 18 and 26 and were weighed at weaning. Adult behavior and location in the cage were recorded by scan samples every 30 min over 48 hr of video recorded on PND 0-8 and PND 14-21 when pups were in the cage. Press posture and play behavior were recorded by 1/0 sampling method. Cage space did not significantly alter typical reproductive measures. Pups in the smallest cage played less than in the other cages. Adults in the smallest cage displayed more press posture than in the two largest cages. Mice in the largest cage spent more time under the feeder than in other areas of the cage. Nest score was also the highest in the largest cage. Housing breeding groups of mice in a range of commercially available cage sizes does not affect reproduction but behavioral measures suggest that the smallest cage tested, LP 18790, may be stressful for outbred mice when pups are present.

  15. Online retrieval of patient information by asynchronous communication between general purpose computer and stand-alone personal computer

    International Nuclear Information System (INIS)

    Tsutsumi, Reiko; Takahashi, Kazuei; Sato, Toshiko; Komatani, Akio; Yamaguchi, Koichi

    1988-01-01

    Asynchronous communication was made between host (FACOM M-340) and personal computer (OLIBETTIE S-2250) to get patient's information required for RIA test registration. The retrieval system consists of a keyboad input of six numeric codes, patient's ID, and a real time reply containing six parameters for the patient. Their identified parameters are patient's name, sex, date of birth (include area), department, and out- or inpatient. Linking this program to RIA registration program for individual patient, then, operator can input name of RIA test requested. Our simple retrieval program made a useful data network between different types of host and stand-alone personal computers, and enabled us accurate and labor-saving registration for RIA test. (author)

  16. Life cycle assessment study of a 4.2 kW{sub p} stand-alone photovoltaic system

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Valverde, R.; Miguel, C.; Urbina, A. [Universidad Politecnica de Cartagena, Departamento de Electronica, Tecnologia de Computadoras y Proyectos, Campus Muralla del Mar, 30203, Cartagena, Murcia (Spain); Martinez-Bejar, R. [Universidad de Murcia, Departamento de Ingenieria de la Informacion y las Comunicaciones, Facultad de Informatica, Campus de Espinardo, 30071, Murcia (Spain)

    2009-09-15

    The energetic and environmental life cycle assessment of a 4.2 kW{sub p} stand-alone photovoltaic system (SAPV) at the University of Murcia (south-east of Spain) is presented. PV modules and batteries are the energetically and environmentally most expensive elements. The energy pay-back time was found to be 9.08 years and the specific CO{sub 2} emissions was calculated as 131 g/kWh. The SAPV system has been environmentally compared with other supply options (diesel generator and Spanish grid) showing lower impacts in both cases. The results show the CO{sub 2}-emission reduction potential of SAPV systems in southern European countries and point out the critical environmental issues in these systems. (author)

  17. Integration of hydrogen energy technologies in stand-alone power systems analysis of the current potential for applications

    International Nuclear Information System (INIS)

    Zoulias, E.I.; Lymberopoulos, N.; Tsoutsos, T.; Glockner, R.; Mydske, H.J.; Vosseler, I.; Gavalda, O.; Taylor, P.

    2006-01-01

    The European study entitled: 'Market Potential Analysis for Introduction of Hydrogen Energy Technology in Stand-Alone Power Systems (H-SAPS)' aimed to establish a broad understanding of the market potential for H-SAPS and provide a basis for promoting in wide scale new technological applications. The scope of the study was limited to small and medium installations, up to a few hundred kW power rating and based on RE as the primary energy source. The potential for hydrogen technology in SAPS was investigated through an assessment of the technical potential for hydrogen, the market analysis and the evaluation of external factors. The results are mostly directed towards action by governments and the research community but also industry involvement is identified. The results include targeted market research, establishment of individual cost targets, regulatory changes to facilitate alternative grid solutions, information and capacity building, focused technology research and bridging the technology gaps. (author)

  18. Biomechanical evaluation of DTRAX® posterior cervical cage stabilization with and without lateral mass fixation

    Directory of Open Access Journals (Sweden)

    Voronov LI

    2016-08-01

    Full Text Available Leonard I Voronov,1,2 Krzysztof B Siemionow,3 Robert M Havey,1,2 Gerard Carandang,2 Avinash G Patwardhan1,2 1Department of Orthopaedic Surgery and Rehabilitation, Loyola University Chicago, Maywood, 2Musculoskeletal Biomechanics Laboratory, Edward Hines Jr. VA Hospital, Hines, 3Department of Orthopaedics, University of Illinois College of Medicine at Chicago, Chicago, IL, USA Introduction: Lateral mass screw (LMS fixation with plates or rods is the current standard procedure for posterior cervical fusion. Recently, implants placed between the facet joints have become available as an alternative to LMS or transfacet screws for patients with cervical spondylotic radiculopathy. The purpose of this study was to evaluate the biomechanical stability of the DTRAX® cervical cage for single- and two-level fusion and compare this to the stability achieved with LMS fixation with rods in a two-level construct.Methods: Seven cadaveric cervical spine (C3–C7 specimens were tested in flexion–extension, lateral bending, and axial rotation to ±1.5 Nm moment without preload (0 N in the following conditions: 1 intact (C3–C7, 2 LMS and rods at C4–C5 and C5–C6, 3 removal of all rods (LMS retained and placement of bilateral posterior cages at C5–C6, 4 bilateral posterior cages at C4–C5 and C5–C6 (without LMS and rods, and 5 C4–C5 and C5–C6 bilateral posterior cages at C4–C5 and C5–C6 with rods reinserted.Results: Bilateral posterior cervical cages significantly reduced range of motion in all tested directions in both single- and multilevel constructs (P<0.05. Similar stability was achieved with bilateral posterior cages and LMS in a two-level construct: 0.6°±0.3° vs 1.2°±0.4° in flexion–­extension (P=0.001, (5.0°±2.6° vs 3.1°±1.3° in lateral bending (P=0.053, (1.3°±1.0° vs 2.2°±0.9° in axial rotation (P=0.091 for posterior cages and LMS, respectively. Posterior cages, when placed as an adjunct to LMS, further reduced

  19. Energy-bounded caging: Formal definition and 2-D energy lower bound algorithm based on weighted alpha shapes

    NARCIS (Netherlands)

    Mahler, Jeffrey; Pokorny, Florian T.; McCarthy, Zoe; van der Stappen, A.F.; Goldberg, Ken

    Caging grasps are valuable as they can be robust to bounded variations in object shape and pose, do not depend on friction, and enable transport of an object without full immobilization. Complete caging of an object is useful but may not be necessary in cases where forces such as gravity are

  20. On the growth of Penaeus indicus experimented in cages at different densities in a selected nursery ground

    Digital Repository Service at National Institute of Oceanography (India)

    Aravindakshan, P.N.; Paulinose, V.T.; Balasubramanian, T.; Menon, P.G.; Kutty, M.K.

    Effect of different densities on the growth of Penaeus indicus was studied in a higly productive nursery ground located at Ramanthuruth Island (lat. 9~'58'50"N, long. 76~'15'40"E) using cages. Eight cages of the same size were placed with prawns...

  1. Spray washing, absorbent corn starch powder and dry time to reduce bacterial numbers on soiled boiler transport cage flooring

    Science.gov (United States)

    Most broilers in the U.S. are transported live to slaughter facilities in cages with fiberglass floors. Cages are often used repeatedly without washing and fecal matter deposited on the floor surface can transfer Campylobacter from one flock to another. Drying feces out between uses is an effectiv...

  2. Extra-peritoneal pressure packing without external pelvic fixation: A life-saving stand-alone surgical treatment

    Directory of Open Access Journals (Sweden)

    Guy Ron

    2015-01-01

    Full Text Available Purpose: Traditional maneuvers aim to decrease retroperitoneal bleeding in hemodynamically unstable multi-trauma patients with unstable pelvic fractures, are reportedly successful in approximately only 50%. The life-saving effect of extra-peritoneal pressure packing (EPPP is based on direct compression and control of both venous and arterial retroperitoneal bleeders. This study describes the safety and efficacy of emergent EPPP employment, as a stand-alone surgical treatment, that is, carried out without external pelvic fixation or emergent angiography. Materials and Methods: A retrospective chart review of all hemodynamic unstable, multi-trauma patients with mechanically unstable pelvic fractures treated by the EPPP technique at our medical center between the years 2005 and 2011. Survival rates, clinical, and physiological outcomes were followed prospectively. Results: Twenty-five of the 181 pelvic fracture patients had biomechanically unstable fractures that required surgical fixation. Fourteen of those 25 patients had deteriorating hemodynamic instability from massive pelvic bleeding which was resistant to resuscitation, and they underwent EPPP, as a stand-alone treatment. The procedure successfully achieved hemodynamic stability in all 14 patients and obviated the early mortality associated with massive pelvic bleeding. Three of these patients eventually succumbed to their multiple injuries. Conclusion: Implementation of EPPP improved all measured physiological outcome parameters and survival rates of hemodynamically unstable multi-trauma patients with unstable pelvic fractures in our trauma center. It provided the unique advantage of directly compressing the life-threatening retroperitoneal bleeders by applying direct pressure and causing a tamponade effect to stanch venous and arterial pelvic blood flow and obviate the early mortality associated with massive pelvic bleeding.

  3. The effects of individually ventilated cages on the respiratory systems of male and female Wistar rats from birth until adulthood

    Science.gov (United States)

    Marchesi, Guilherme D’Aprile; de Fatima Soto, Sônia; de Castro, Isac; Rodrigues, Thiago Guimarães; Moriya, Henrique Takachi; de Almeida, Francine Maria; Pazetti, Rogerio; Heimann, Joel Claudio; Furukawa, Luzia Naôko Shinohara

    2017-01-01

    OBJECTIVE: To evaluate the respiratory systems of male and female rats maintained in individually ventilated cages (IVCs) from birth until adulthood. METHODS: Female Wistar rats were housed in individually ventilated cages or conventional cages (CCs) and mated with male Wistar rats. After birth and weaning, the male offspring were separated from the females and kept in cages of the same type until 12 weeks of age. RESULTS: The level of food consumption was lower in male offspring (IVC=171.7±9; CC=193.1±20) than in female offspring (IVC=100.6±7; CC=123.4±0.4), whereas the water intake was higher in female offspring (IVC=149.8±11; CC=99.2±0) than in male offspring (IVC=302.5±25; CC=249.7±22) at 11 weeks of age when housed in IVCs. The cage temperature was higher in individually ventilated cages than in conventional cages for both male (IVCs=25.9±0.5; CCs=22.95±0.3) and female (IVCs=26.2±0.3; CCs=23.1±0.3) offspring. The respiratory resistance (IVC=68.8±2.8; CC=50.6±3.0) and elastance (IVC=42.0±3.9; CC=32.4±2.0) at 300 µm/kg were higher in the female offspring housed in ventilated cages. The ciliary beat values were lower in both the male (IVCs=13.4±0.2; CC=15±0.4) and female (IVC=13.5±0.4; CC=15.9±0.6) offspring housed in individually ventilated cages than in those housed in conventional cages. The total cell (IVC=117.5±9.7; CC=285.0±22.8), neutrophil (IVC=13.1±4.8; CC=75.6±4.1) and macrophage (IVC=95.2±11.8; CC=170.0±18.8) counts in the bronchoalveolar lavage fluid were lower in the female offspring housed in individually ventilated cages than in those housed in conventional cages. CONCLUSIONS: The environmental conditions that exist in individually ventilated cages should be considered when interpreting the results of studies involving laboratory animals. In this study, we observed gender dimorphism in both the water consumption and respiratory mechanics of rats kept in ventilated cages. PMID:28355363

  4. Acclimatization of mice to different cage types and social groupings with respect to fecal secretion of IgA and corticosterone metabolites

    DEFF Research Database (Denmark)

    Bundgaard, Cathrine Juel; Kalliokoski, Otto; Abelson, Klas Sp

    2012-01-01

    Stress associated with transport and change of environment may have widespread effects on physiological parameters in laboratory animals. To investigate the time needed for mice to acclimatize to a new environment, based on fecal IgA and corticosterone excretion, eightweek-old BALB/c mice of both...... genders were housed either in groups of eight in different cage types in open conventional cages, in Individual Ventilated Cages (IVC), in open conventional cages inside a plastic isolator, or in different group sizes (8, 4, 8, 10 or 12 mice in each group) in open conventional cages. Feces were collected...... from each cage on routine cage changing. There was no significant difference in corticosterone excretion in feces between animals housed in the different cage types or between animals housed in different group sizes. IgA excretion for both males and females was found to be affected by transfer of mice...

  5. INTERACTIVE EFFECT OF CAGE DENSITY AND DIETARY BLACK CUMIN LEVEL ON PRODUCTIVE EFFICIENCY IN BROILER CHICKENS

    Directory of Open Access Journals (Sweden)

    L. D. Mahfudz

    2015-09-01

    Full Text Available The present research was aimed to evaluate an interactive effect of cage density and level ofdietary black cumin (BC on productive efficiency of broiler chickens. A total of 270 broiler chickens(initial body weight of 163.12 ± 8.10g were allocated into a completely randomized design with a 3 x 3factorial pattern. The first factor was the cage density (bird/m2 namely, D1 = 8; D2 = 10, and D3 = 12.The second factor was BC level (%, namely, B1 = 1; B2 = 2, and B3 = 3. Feed consumption, bodyweight gain (BWG, feed conversion ratio (FCR, protein digestibility, and income over feed cost(IOFC were the parameters measured. Data were subjected to ANOVA and continued to Duncan test.No interaction between cage density and black cumin on all parameters was observed. Feedconsumption and FCR were increased, but BWG was lowered significantly (P<0.05 due to the cagedensities of 10 and 12 birds/m2 on weeks 2 and 3. Protein digestibility was significantly increased byfeeding 2 and 3% BC. IOFC decreased significantly (P<0.05 when cage densities were 10 and 12birds/m2. In conclusion, the improvement of productive efficiency of broiler chicken reared at the cagedensity of 12 birds /m2 can be sufficiently achieved by feeding 1% black cumin.

  6. Romantic Remediation? John Cage and Henry David Thoreau’s Walden State of Mind

    NARCIS (Netherlands)

    Mehring, F.

    2014-01-01

    Rather than identifying Cage as a romantic soul mate of the transcendentalists exhibiting a rebellious attitude against conventions, I will investigate new ways to detect with greater exactness what Sean Wilentz described in the context of David S. Reynolds work on the American Renaissance as “the

  7. Urea and Guanidinium Induced Denaturation of a Trp-Cage Miniprotein

    Czech Academy of Sciences Publication Activity Database

    Heyda, Jan; Kožíšek, Milan; Bednárová, Lucie; Thompson, G.; Konvalinka, Jan; Vondrášek, Jiří; Jungwirth, Pavel

    2011-01-01

    Roč. 115, č. 28 (2011), s. 8910-8924 ISSN 1520-6106 R&D Projects: GA MŠk LC512; GA ČR GA203/08/0114 Institutional research plan: CEZ:AV0Z40550506 Keywords : trp-cage denaturation * urea * guanidinium * molecular dynamics Subject RIV: CC - Organic Chemistry Impact factor: 3.696, year: 2011

  8. That Entertainment Called a Discussion: The Critical Arts Pedagogy of John Cage

    Science.gov (United States)

    Muller, Otto

    2015-01-01

    Just as John Cage used chance techniques to relinquish control in his practice as a composer, he used pedagogical techniques that facilitated shared learning and experimentation. The tenets of Critical Pedagogy, as laid out by Paulo Freire in "The Pedagogy of the Oppressed," offer insights into the structures and strategies implicit in…

  9. Effect of cage tier and age on performance, egg quality and stress ...

    African Journals Online (AJOL)

    The effects of cage tiers on week 42 BW, feed conversion ratio (FCR), tonic immobility (TI), egg weight (EW), egg yield (EY), and most external and internal quality traits of the hens' eggs were found to be insignificant. Except for shape index (SI) and albumen pH, internal and external quality traits of eggs were significantly ...

  10. the benefits of the cage as a screening tool for alcoholism in a ...

    African Journals Online (AJOL)

    diseases such as tuberculosis, the leading notifiable disease in. South Africa.17. The 'CAGE' acronym, representing a four-item test with questions on 'Cutting down, Armoyance at criticism, Guilty feelings and use of Eye-openers' (Table 1) was first described by. Ewing in 1970. It is one of several questionnaires designed to.

  11. Behavior and Welfare of Domestic Cats Housed in Cages Larger than U.S. Norm.

    Science.gov (United States)

    Stella, Judith L; Croney, Candace C; Buffington, C Tony

    2017-01-01

    The effect of providing additional floor space on cat behavior and welfare is not well documented. This study involved replication of an investigation of cats' responses to enhanced cage and room environments using cages of 0.56 m 2 with the same methodology but an increased space allowance of 1.1 m 2 . Singly housed adult cats (n = 59) were randomly assigned to a treatment group that was a combination of a managed or unmanaged room and an enriched or unenriched cage environment. Cats were observed for 2 days for maintenance, affiliative, and avoidant behaviors using scan sampling and 5-min, continuous focal sampling. At the end of Day 2, cats' reactions to the approach of an unfamiliar person were assessed. Cats housed in enriched/managed environments exhibited more maintenance and affiliative behaviors and fewer avoidant behaviors than cats in unmanaged/unenriched environments, suggesting that macro and micro environments may be equally relevant to the cat. Increased space did not enhance the cats' welfare outcomes, suggesting that the provision of additional cage space may not be as important to the cat as a managed housing environment.

  12. Stability of gold cages (Au16 and Au17) at finite temperature

    Indian Academy of Sciences (India)

    2015-11-27

    Nov 27, 2015 ... We have employed ab initio molecular dynamics to investigate the stability of the smallest gold cages, namely Au16 and Au17, at finite temperatures. First, we obtain the ground state structure along with at least 50 distinct isomers for both the clusters. This is followed by the finite temperature simulations of ...

  13. Fish cage culture catches on in Nepal | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... for their children, unlike many rural communities in Nepal. And the role of women in decision-making has been strengthened. Women take part alongside the men in all activities, from cleaning and repairing the fish cages to participating in meetings of farmers'' associations, attending workshops, and marketing the catch.

  14. Methodology for the nuclear design validation of an Alternate Emergency Management Centre (CAGE)

    International Nuclear Information System (INIS)

    Hueso, C.; De La Fuente, C.; Janes, A.; Massuet, J.; Zamora, I.; Fabbri, M.; Gasca, C.; Hernandez, H.; Angel Vega, J.

    2017-01-01

    As a consequence of the Fukushima accident, Spanish nuclear authorities have decided to equip each nuclear power plant with an Alternate Emergency Management Centre (CAGE) that will manage safely any emergency occurring on the site. The living conditions of the occupants of the CAGE in the event of a Severe Accident imply that TEDE (Total Effective Dose Equivalent) must be<50 mSv and the equivalent dose to the thyroid<500 mSv within 30 days following the accident. This paper presents the methodology followed to design CAGE in order to comply with above dose limits. The study of weather conditions as part of the data of the site will determine the relative concentrations of radionuclides in the air using ARCON96. The activity in the air is characterized depending on the source and release sequence specified in NUREG-1465 by RADTRAD code, which provides results of the inner cloud source term contribution. Known activities and energy spectra are inferred using ORIGEN-S, which are used as input for the models of the outer cloud, filters and containment generated with MCNP5. The sum of the different contributions must be below radiation dose limits. The radiation dose is optimized by varying parameters including CAGE location on the plant site, flow filtering need for recirculation, thicknesses and compositions of the walls, etc. The calculation codes selected for the development of this methodology are widely available, internationally used and validated in many studies

  15. Le marécage de Fouwarate (Kenitra, Maroc) : site de conservation d ...

    African Journals Online (AJOL)

    ouest de la plaine littorale du Gharb, sur le cours de l'oued Fouwarate, petit affluent du cours terminal de l'oued Sebou. Cette zone humide est l'un des derniers représentant d'un complexe de marécages qui occupait ladite plaine et qui offrait ...

  16. Assessing mouse behaviour throughout the light/dark cycle using automated in-cage analysis tools.

    Science.gov (United States)

    Bains, Rasneer S; Wells, Sara; Sillito, Rowland R; Armstrong, J Douglas; Cater, Heather L; Banks, Gareth; Nolan, Patrick M

    2018-04-15

    An important factor in reducing variability in mouse test outcomes has been to develop assays that can be used for continuous automated home cage assessment. Our experience has shown that this has been most evidenced in long-term assessment of wheel-running activity in mice. Historically, wheel-running in mice and other rodents have been used as a robust assay to determine, with precision, the inherent period of circadian rhythms in mice. Furthermore, this assay has been instrumental in dissecting the molecular genetic basis of mammalian circadian rhythms. In teasing out the elements of this test that have determined its robustness - automated assessment of an unforced behaviour in the home cage over long time intervals - we and others have been investigating whether similar test apparatus could be used to accurately discriminate differences in distinct behavioural parameters in mice. Firstly, using these systems, we explored behaviours in a number of mouse inbred strains to determine whether we could extract biologically meaningful differences. Secondly, we tested a number of relevant mutant lines to determine how discriminative these parameters were. Our findings show that, when compared to conventional out-of-cage phenotyping, a far deeper understanding of mouse mutant phenotype can be established by monitoring behaviour in the home cage over one or more light:dark cycles. Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

  17. Rate constant and reaction coordinate of Trp-cage folding in explicit water

    NARCIS (Netherlands)

    Juraszek, J.; Bolhuis, P.G.

    2008-01-01

    We report rate constant calculations and a reaction coordinate analysis of the rate-limiting folding and unfolding process of the Trp-cage mini-protein in explicit solvent using transition interface sampling. Previous transition path sampling simulations revealed that in this (un)folding process the

  18. Effects of three agricultural by-products on cage culture growth ...

    African Journals Online (AJOL)

    In man-made Lake Ayame, a 180-day cage culture feeding trial was conducted to investigate the effects of three agricultural byproducts — chicken droppings, wheat bran and corn bran — on the survival rates, mean daily weight gain and feed conversion ratio in juveniles of a landlocked population of Sarotherodon ...

  19. Sternum Length and Rib Cage Dimensions Compared with Bodily Proportions in Adults with Cystic Fibrosis

    Directory of Open Access Journals (Sweden)

    Louis-Philippe Laurin

    2012-01-01

    Full Text Available BACKGROUND: A greater structural expansion of the rib cage in females compared with males has been described in cystic fibrosis (CF patients; however, conflicting data exist as to whether an elongation of the bony ribs and sternum contributes to this expansion.

  20. Cage occupancies in the high pressure structure H methane hydrate: a neutron diffraction study.

    Science.gov (United States)

    Tulk, C A; Klug, D D; dos Santos, A M; Karotis, G; Guthrie, M; Molaison, J J; Pradhan, N

    2012-02-07

    A neutron diffraction study was performed on the CD(4) : D(2)O structure H clathrate hydrate to refine its CD(4) fractional cage occupancies. Samples of ice VII and hexagonal (sH) methane hydrate were produced in a Paris-Edinburgh press and in situ neutron diffraction data collected. The data were analyzed with the Rietveld method and yielded average cage occupancies of 3.1 CD(4) molecules in the large 20-hedron (5(12)6(8)) cages of the hydrate unit cell. Each of the pentagonal dodecahedron (5(12)) and 12-hedron (4(3)5(6)6(3)) cages in the sH unit cell are occupied with on average 0.89 and 0.90 CD(4) molecules, respectively. This experiment avoided the co-formation of Ice VI and sH hydrate, this mixture is more difficult to analyze due to the proclivity of ice VI to form highly textured crystals, and overlapping Bragg peaks of the two phases. These results provide essential information for the refinement of intermolecular potential parameters for the water-methane hydrophobic interaction in clathrate hydrates and related dense structures.