Sample records for stall charge qs

  1. QS-21: a potent vaccine adjuvant (United States)

    QS-21 is an potent adjuvant derived from the bark of a Chilean tree, Quillaja saponaria. One of the advantages of this adjuvant is that it promotes a balanced humoral and cell-mediaed immune response and can be widely applicable to a variety of vaccines. This adjuvant has used for some veterinary va...

  2. QS Spiral: Visualizing Periodic Quantified Self Data

    DEFF Research Database (Denmark)

    Larsen, Jakob Eg; Cuttone, Andrea; Jørgensen, Sune Lehmann


    In this paper we propose an interactive visualization technique QS Spiral that aims to capture the periodic properties of quantified self data and let the user explore those recurring patterns. The approach is based on time-series data visualized as a spiral structure. The interactivity includes ...

  3. Opening the black box of QS World University Rankings


    Mu-Hsuan Huang


    In the era of globalization, the trend of university rankings gradually shifts from country-wide analyses to world-wide analyses. Relatively high analytical weightings on reputational surveys have led Quacquarelli Symonds (QS) World University Rankings to criticisms over the years. This study provides a comprehensive discussion of the indicators and weightings adopted in the QS survey. The article discusses several debates stirred in the academia on QS. Debates on this ranking system are pres...

  4. 14 CFR 25.103 - Stall speed. (United States)


    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Stall speed. 25.103 Section 25.103... STANDARDS: TRANSPORT CATEGORY AIRPLANES Flight Performance § 25.103 Stall speed. (a) The reference stall speed, VSR, is a calibrated airspeed defined by the applicant. VSR may not be less than a 1-g stall...

  5. 14 CFR 25.203 - Stall characteristics. (United States)


    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Stall characteristics. 25.203 Section 25.203 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Flight Stalls § 25.203 Stall characteristics. (a) It must...

  6. The THE-QS World University Rankings, 2004 – 2009

    Directory of Open Access Journals (Sweden)

    Richard Holmes


    Full Text Available This paper reviews the origin, development and demise of the Times Higher Education Supplement (now Times Higher Education – QS Quacquarelli Symonds (QS World University Rankings between 2004 and 2009. It describes the structure and methodology of the rankings, their public impact and various criticisms that have been made. It also analyses changes that were introduced between 2005 and 2009 and concludes by noting the development of two distinct ranking systems by the magazine Times Higher Education (THE and by its former partner, the consulting company Quacquarelli Symonds.

  7. Exercising QS: Quantitative Skills in an Exercise Science Course (United States)

    Wilson, T. M.


    This study seeks to bring the discipline of exercise science into the discussion of Quantitative Skills (QS) in science. The author's experiences of providing learning support to students and working with educators in the field are described, demonstrating the difficulty of encouraging students to address their skills deficit. A survey of…

  8. Skeletonized wave-equation Qs tomography using surface waves

    KAUST Repository

    Li, Jing


    We present a skeletonized inversion method that inverts surface-wave data for the Qs quality factor. Similar to the inversion of dispersion curves for the S-wave velocity model, the complicated surface-wave arrivals are skeletonized as simpler data, namely the amplitude spectra of the windowed Rayleigh-wave arrivals. The optimal Qs model is then found that minimizes the difference in the peak frequencies of the predicted and observed Rayleigh wave arrivals using a gradient-based wave-equation optimization method. Solutions to the viscoelastic wave-equation are used to compute the predicted Rayleigh-wave arrivals and the misfit gradient at every iteration. This procedure, denoted as wave-equation Qs tomography (WQs), does not require the assumption of a layered model and tends to have fast and robust convergence compared to Q full waveform inversion (Q-FWI). Numerical examples with synthetic and field data demonstrate that the WQs method can accurately invert for a smoothed approximation to the subsur-face Qs distribution as long as the Vs model is known with sufficient accuracy.

  9. Wave-equation Qs Inversion of Skeletonized Surface Waves

    KAUST Repository

    Li, Jing


    We present a skeletonized inversion method that inverts surface-wave data for the Qs quality factor. Similar to the inversion of dispersion curves for the S-wave velocity model, the complicated surface-wave arrivals are skeletonized as simpler data, namely the amplitude spectra of the windowed Rayleigh-wave arrivals. The optimal Qs model is the one that minimizes the difference in the peak frequencies of the predicted and observed Rayleigh wave arrivals using a gradient-based wave-equation optimization method. Solutions to the viscoelastic wave-equation are used to compute the predicted Rayleigh-wave arrivals and the misfit gradient at every iteration. This procedure, denoted as wave-equation Qs inversion (WQs), does not require the assumption of a layered model and tends to have fast and robust convergence compared to full waveform inversion (FWI). Numerical examples with synthetic and field data demonstrate that the WQs method can accurately invert for a smoothed approximation to the subsurface Qs distribution as long as the Vs model is known with sufficient accuracy.

  10. Clutch-Starting Stalled Research Students (United States)

    Ahern, Kathy; Manathunga, Catherine


    Many research students go through periods where their research seems to stall, their motivation drops, and they seem unable to make any progress. As supervisors, we attempt to remain alert to signs that our student's progress has stalled. Drawing on cognitive strategies, this article explores a problem-solving model supervisors can use to identify…

  11. Basis for an Active Stall Avoidance System

    Directory of Open Access Journals (Sweden)

    Richard Schulze


    Full Text Available A single-stage subsonic compressor was examined with respect to compressor instabilities. During the inception of rotating stall, the transients of the pressure rise and mass flow were measured as well as their hysteresis. The development of the stall cell and the characteristics of the unstable operating range were determined.

  12. Construction of hydrogenation stalls for explosions

    Energy Technology Data Exchange (ETDEWEB)

    Raichle, L.


    This report contained explanations for different questions that had been asked by the Association of Chemical Manufacturers. The first item discussed was the pressure occurring in hydrogenation stalls in hydrogen explosions. The pressures actually used were much smaller than the maximum design pressure due to burning gases being allowed to escape from the top and front of the stalls since these areas were open and it could not be assumed that the whole stall space was filled with a 32% hydrogen concentration at the beginning of an explosion. The second item discussed was specifications and rules for the building of hydrogenation stalls. These included the calculations for simple wind pressure according to the Building Code with the usual safety factors and the calculations for an inner pressure of 300 kg/m/sup 2/ with the usual safety factors. An explanation of a stall explosion in Poelitz and reinforced stall construction in Poelitz were two other items that were discussed. Appendix I of the report involved maximum pressures and temperature in hydrogen explosions. Diagram I was involved with this. Appendix II discussed the behavior of a hydrogen flame at high emerging velocities and Appendix III discussed stall construction at Poelitz.

  13. Atomic Model and Micelle Dynamics of QS-21 Saponin

    Directory of Open Access Journals (Sweden)

    Conrado Pedebos


    Full Text Available QS-21 is a saponin extracted from Quillaja saponaria, widely investigated as a vaccine immunoadjuvant. However, QS-21 use is mainly limited by its chemical instability, significant variety in molecular composition and low tolerance dose in mammals. Also, this compound tends to form micelles in a concentration-dependent manner. Here, we aimed to characterize its conformation and the process of micelle formation, both experimentally and computationally. Therefore, molecular dynamics (MD simulations were performed in systems containing different numbers of QS-21 molecules in aqueous solution, in order to evaluate the spontaneous micelle formation. The applied methodology allowed the generation of micelles whose sizes were shown to be in high agreement with small-angle X-ray scattering (SAXS. Furthermore, the ester linkage between fucose and acyl chain was less solvated in the micellar form, suggesting a reduction in hydrolysis. This is the first atomistic interpretation of previous experimental data, the first micellar characterization of saponin micelles by SAXS and first tridimensional model of a micelle constituted of saponins, contributing to the understanding of the molecular basis of these compounds.

  14. The Relevance of the Dynamic Stall Effect for Transient

    DEFF Research Database (Denmark)

    Jauch, Clemens; Sørensen, Poul; Bak-Jensen, Birgitte


    This article describes a methodology to quantify the influence of dynamic stall on transient fault operations of active-stall turbines. The model of the dynamic stall effect is introduced briefly. The behaviour of the dynamic stall model during a transient fault operation is described mathematica...

  15. Biomimetic Wind Turbine Design with Lift Enhancing Periodic Stall

    NARCIS (Netherlands)

    Stamhuis, Eize Jan


    A wind turbine includes a rotor; a blade; and a periodic stall system. The periodic stall system selectively moves at least part of the blade in an oscillating motion whereby an angle of incidence continuously varies to invoke periodic stall. The periodic stall system can move the entire blade or

  16. Prediction of induced vibrations in stall

    Energy Technology Data Exchange (ETDEWEB)

    Thirstrup Petersen, J.; Thomsen, K.; Aagaard Madsen, H. [Risoe National Lab., Wind Energy and Atmospheric Physics Dept., Roskilde (Denmark)


    The main results from recent research in stall induced vibrations are presented. The focus is on the edgewise blade vibrations, which during the last decade have turned out to be a potential threat against the stable operation of stall regulated wind turbines and a fact, which must be dealt with by the designer. The basic physical explanation for the phenomenon and examples of design precaution, which can be taken, are presented. (au)

  17. Plasma-based Compressor Stall Control (United States)

    McGowan, Ryan; Corke, Thomas


    The use of dielectric barrier discharge (DBD) plasma actuator casing treatment to prevent or delay stall inception in an axial fan is examined. The actuators are powered by a pulsed-DC waveform which induces a larger peak velocity than a purely AC waveform such as a sine or sawtooth wave. With this system, a high-voltage DC source is supplied to both electrodes, remaining constant in time for the exposed electrode. Meanwhile, the covered electrode is periodically grounded for several microseconds and allowed to rise back to the source DC level. To test the actuators' ability to interact with and modify the formation of stall cells, a facility has been designed and constructed around nonconductive fan blades. The actuators are installed in the fan casing near the blade tips. The instrumentation allows for the measurement of rotating pressure disturbances (traveling stall cells) in this tip gap region as well as fan performance characteristics including pressure rise and flow rate. The casing plasma actuation is found to reduce the correlation of the rotating stall cells, thereby extending the stall margin of the fan. Various azimuthal arrangements of the plasma actuator casing treatment is explored, as well as input voltage levels to the actuator to determine optimum conditions. NASA SBIR Contract NNX14CC12C.

  18. The relevance of the dynamic stall effect for transient fault operations of active-stall wind turbines

    Energy Technology Data Exchange (ETDEWEB)

    Jauch, Clemens; Soerensen, Poul; Jensen, Birgitte Bak


    This article describes a methodology to quantify the influence of dynamic stall on transient fault operations of active-stall turbines. The model of the dynamic stall effect is introduced briefly. The behaviour of the dynamic stall model during a transient fault operation is described mathematically, and from this its effect quantified. Two quantities are chosen to describe the influence of the dynamic stall effect: one is active power and the other is time delay. Subsequently a transient fault scenario is simulated with and without the dynamic stall effect and the differences discussed. From this comparison, the conclusion is drawn that the dynamic stall effect has some influence on the post-fault behaviour of the wind turbine, and it is hence suggested that the dynamic stall effect is considered if an active-stall wind turbine is to be modelled realistically. (Author)

  19. Load prediction of stall regulated wind turbines

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerck, A.; Dahlberg, J.Aa. [Aeronautical Research Inst. of Sweden, Bromma (Sweden); Carlen, I. [Chalmers Univ. of Technology, Goeteborg (Sweden). Div. of Marine Structural Engineering; Ganander, H. [Teknikgruppen AB, Sollentua (Sweden)


    Measurements of blade loads on a turbine situated in a small wind farm shows that the highest blade loads occur during operation close to the peak power i.e. when the turbine operates in the stall region. In this study the extensive experimental data base has been utilised to compare loads in selected campaigns with corresponding load predictions. The predictions are based on time domain simulations of the wind turbine structure, performed by the aeroelastic code VIDYN. In the calculations a model were adopted in order to include the effects of dynamic stall. This paper describes the work carried out so far within the project and key results. 5 refs, 10 figs

  20. Dynamic stall and 3D effects

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerck, A.; Thor, S.E. [Aeronautical Research Inst. of Sweden, Bromma (Sweden)


    The JOULE II project `Dynamic stall and 3D effects` started in January 1994 and was completed in September 1995. The objective of the project has been to increase the understanding of the three-dimensional and unsteady aerodynamics of stall controlled HAWT`s. The objectives have also been to develop `engineering models` suitable for inclusion into aero-elastic codes. The project included the participation of 13 parties within Europe. This paper describes an overview of the work carried out within the project and key results. 3 refs, 4 figs

  1. Education stalls and subsequent stalls in African fertility: A descriptive overview

    Directory of Open Access Journals (Sweden)

    Anne Goujon


    Full Text Available Background: Recent stalls in fertility decline have been observed in a few countries in sub-Saharan Africa, and so far no plausible common reason has been identified in the literature. This paper develops the hypothesis that these fertility stalls could be associated with stalls in the progress of education among the women of the relevant cohorts, possibly resulting partly from the Structural Adjustment Programs (SAPs of the 1980s. Methods: We descriptively link the change in the education composition of successive cohorts of young women in sub-Saharan Africa and the recent fertility stalls. We use reconstructed data on population by age, gender, and level of education from www.wittgenstein, and fertility rates from the United Nations. Results: In most sub-Saharan African countries, we observe that the same countries that had fertility stalls had a stall in the progress of education, particularly for young women who were of primary school age during the 1980s, when most of the countries were under structural adjustment. Conversely, stalls in fertility are less common in countries that did not have an education stall, possibly in relation to SAPs. Conclusions: The results point to the possibility of a link between the recent fertility stalls and discontinuities in the improvement of the education of the relevant cohorts, which in turn could be related to the SAPs in the 1980s. This descriptive finding now needs to be corroborated through more detailed cohort-specific fertility analysis. If the education-fertility link can be further established, it will have important implications for the projections of population growth in affected countries.

  2. Calculation of Rotor Performance and Loads Under Stalled Conditions

    National Research Council Canada - National Science Library

    Yeo, Hyeonsoo


    Rotor behavior in stalled conditions is investigated using wind tunnel test data of a 1/10-scale CH-47B/C type rotor, which provides a set of test conditions extending from unstalled to light stall...

  3. Airfoil stall interpreted through linear stability analysis (United States)

    Busquet, Denis; Juniper, Matthew; Richez, Francois; Marquet, Olivier; Sipp, Denis


    Although airfoil stall has been widely investigated, the origin of this phenomenon, which manifests as a sudden drop of lift, is still not clearly understood. In the specific case of static stall, multiple steady solutions have been identified experimentally and numerically around the stall angle. We are interested here in investigating the stability of these steady solutions so as to first model and then control the dynamics. The study is performed on a 2D helicopter blade airfoil OA209 at low Mach number, M 0.2 and high Reynolds number, Re 1.8 ×106 . Steady RANS computation using a Spalart-Allmaras model is coupled with continuation methods (pseudo-arclength and Newton's method) to obtain steady states for several angles of incidence. The results show one upper branch (high lift), one lower branch (low lift) connected by a middle branch, characterizing an hysteresis phenomenon. A linear stability analysis performed around these equilibrium states highlights a mode responsible for stall, which starts with a low frequency oscillation. A bifurcation scenario is deduced from the behaviour of this mode. To shed light on the nonlinear behavior, a low order nonlinear model is created with the same linear stability behavior as that observed for that airfoil.

  4. 16 CFR 1505.50 - Stalled motor testing. (United States)


    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Stalled motor testing. 1505.50 Section 1505... USE BY CHILDREN Policies and Interpretations § 1505.50 Stalled motor testing. (a) § 1505.6(e)(4)(ii) requires that a motor-operated toy be tested with the motor stalled if the construction of the toy is such...

  5. The Quantified Self (QS) Movement and Some Emerging Opportunities for the Educational Technology Field (United States)

    Lee, Victor R.


    The Quantified Self (QS) movement is a growing global effort to use new mobile and wearable technologies to automatically obtain personal data about everyday activities. The social and material infrastructure associated with the Quantified Self (QS) movement provides a number of ideas that educational technologists should consider incorporating…

  6. Synthesis and structure verification of the vaccine adjuvant QS-7-Api. Synthetic access to homogeneous Quillaja saponaria immunostimulants. (United States)

    Deng, Kai; Adams, Michelle M; Gin, David Y


    QS-7-Api is an exceedingly potent immuno-adjuvant isolated from the bark of Quillaja saponaria. It is significantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in anticancer and antiviral vaccine clinical trials. Tedious isolation/purification protocols and uncertainty in its structural constitution have hindered the clinical development of QS-7. A chemical synthesis of QS-7-Api is described, providing structural verification of the adjuvant. A novel semisynthetic sequence to QS-7-Api has also been established, greatly facilitating access to QS-7 for preclinical and clinical evaluation.

  7. Simulation model of an active stall wind turbine controller

    Energy Technology Data Exchange (ETDEWEB)

    Jauch, C.; Hansen, A.D.; Soerensen, P. [Risoe National Lab., Wind Energy Dept., Rosilde (Denmark); Blaabjerg, F. [Aalborg Univ., Inst. of Energy Technology (Denmark)


    This paper describes an active stall wind turbine controller. The objective is to develop a general model of an active stall controller in order to simulate the operation of grid connected active stall wind turbines. The active stall turbine concept and its control strategies are presented and evaluated on the basis of simulations. The presented controller is described for continuous operation under all wind speeds from start-up wind speed to shut doven wind speed. Due to its parametric implementation it is general i.e. it can represent different active stall wind turbine controllers and can be implemented in different simulation tools. (au)

  8. Numerical Investigations of Dynamic Stall Control

    Directory of Open Access Journals (Sweden)



    Full Text Available In this paper we investigated numerically the dynamic stall phenomenon and the possibilities to control it, with application to vertical axis wind turbines (for urban users. The Phenomenon appear at low tip speed ratio (TSR<4 and it has a great impact on structural integrity of the wind turbine and power performances. For this reason we performed a computational study of dynamic stall around NACA 0012 airfoil in pitching motion at relative low Reynolds number (105. Also, we performed the same analysis for four flow control methods: two passive (Gurney flap and slot and two active (blowing jet on the rounded trailing edge and synthetic jet periodically activated. The Results are compared to those of an existing experimental case test.

  9. Accounting for biases in riboprofiling data indicates a major role for proline in stalling translation. (United States)

    Artieri, Carlo G; Fraser, Hunter B


    The recent advent of ribosome profiling-sequencing of short ribosome-bound fragments of mRNA-has offered an unprecedented opportunity to interrogate the sequence features responsible for modulating translational rates. Nevertheless, numerous analyses of the first riboprofiling data set have produced equivocal and often incompatible results. Here we analyze three independent yeast riboprofiling data sets, including two with much higher coverage than previously available, and find that all three show substantial technical sequence biases that confound interpretations of ribosomal occupancy. After accounting for these biases, we find no effect of previously implicated factors on ribosomal pausing. Rather, we find that incorporation of proline, whose unique side-chain stalls peptide synthesis in vitro, also slows the ribosome in vivo. We also reanalyze a method that implicated positively charged amino acids as the major determinant of ribosomal stalling and demonstrate that it produces false signals of stalling in low-coverage data. Our results suggest that any analysis of riboprofiling data should account for sequencing biases and sparse coverage. To this end, we establish a robust methodology that enables analysis of ribosome profiling data without prior assumptions regarding which positions spanned by the ribosome cause stalling. © 2014 Artieri and Fraser; Published by Cold Spring Harbor Laboratory Press.

  10. Dynamic Stall Control Using Plasma Actuators (United States)

    Webb, Nathan; Singhal, Achal; Castaneda, David; Samimy, Mo


    Dynamic stall occurs in many applications, including sharp maneuvers of fixed wing aircraft, wind turbines, and rotorcraft and produces large unsteady aerodynamic loads that can lead to flutter and mechanical failure. This work uses flow control to reduce the unsteady loads by excitation of instabilities in the shear layer over the separated region using nanosecond pulse driven dielectric barrier discharge (NS-DBD) plasma actuators. These actuators have been shown to effectively delay or mitigate static stall. A wide range of flow parameters were explored in the current work: Reynolds number (Re = 167,000 to 500,000), reduced frequency (k = 0.025 to 0.075), and excitation Strouhal number (Ste = 0 to 10). Based on the results, three major conclusions were drawn: (a) Low Strouhal number excitation (Ste eliminated the dynamic stall vortex (DSV), thereby dramatically reducing the unsteady loading. The decrease in the strength of the DSV is achieved by the formation of shear layer coherent structures that bleed the leading-edge vorticity prior to the ejection of the DSV.

  11. 14 CFR 23.201 - Wings level stall. (United States)


    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Wings level stall. 23.201 Section 23.201 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS.... Starting from a speed at least 10 knots above the stall speed, the elevator control must be pulled back so...

  12. 14 CFR 33.65 - Surge and stall characteristics. (United States)


    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Surge and stall characteristics. 33.65 Section 33.65 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... stall characteristics. When the engine is operated in accordance with operating instructions required by...

  13. Compressible dynamic stall vorticity flux control using a dynamic ...

    Indian Academy of Sciences (India)

    management of its unsteady vorticity using a variable droop leading edge (VDLE) airfoil. Through ... the pressure gradient term for the dynamic stall conditions encountered by a helicopter-rotor retreating blade. Thus ... This paper discusses control of compressible dynamic stall using the novel idea of variable droop leading ...

  14. Three double-blind, randomized trials evaluating the safety and tolerance of different formulations of the saponin adjuvant QS-21. (United States)

    Waite, D C; Jacobson, E W; Ennis, F A; Edelman, R; White, B; Kammer, R; Anderson, C; Kensil, C R


    The effects of the adjuvant QS-21 in various formulations on immediate pain on injection after intramuscular injection were evaluated in three Phase I clinical trials in healthy adults. Each trial was designed as a double-blind, randomized, four-way or five-way cross-over study with each subject acting as his/her own control. In the first trial, four formulations designed to evaluate the effect of QS-21 or pH (over a range of 6--7.2) were evaluated: phosphate-buffered saline at pH 6.0 or 7.2, and 50 microg of QS-21 in phosphate-buffered saline at pH 6.0 or 7.2. Thirty-three volunteers received each of the four intramuscular injections in random order separated by approximately 1 week. The volunteers assessed the immediate injection pain from 0 to 10 (none to most pain). The data indicate that the presence of QS-21, but not pH, is associated with transient injection site pain. The second trial, which utilized the same design as the first trial, evaluated formulations of QS-21 in various excipients. Fifteen volunteers received phosphate-buffered saline, QS-21/PBS, QS-21/aluminum hydroxide, and QS-21/4 mg/ml of polysorbate 80. Polysorbate 80, but not aluminum hydroxide, reduced the mean pain score compared to QS-21/PBS. The third trial evaluated formulations of QS-21 in additional excipients. Fifteen volunteers received aluminum hydroxide (without QS-21), QS-21/PBS, QS-21/0.72% benzyl alcohol, QS-21/30 mg/ml of hydroxypropyl-beta-cyclodextrin, and QS-21/8-mg/ml of polysorbate 80. Benzyl alcohol, cyclodextrin, and the higher concentration of polysorbate 80 reduced the pain scores associated with QS-21. Hence, QS-21 is associated with injection pain in simple buffer formulations, but it is possible to improve the acceptability of QS-21-containing formulations through reformulation with certain excipients.

  15. Theoretical analysis of transcription process with polymerase stalling (United States)

    Li, Jingwei; Zhang, Yunxin


    Experimental evidence shows that in gene transcription RNA polymerase has the possibility to be stalled at a certain position of the transcription template. This may be due to the template damage or protein barriers. Once stalled, polymerase may backtrack along the template to the previous nucleotide to wait for the repair of the damaged site, simply bypass the barrier or damaged site and consequently synthesize an incorrect messenger RNA, or degrade and detach from the template. Thus, the effective transcription rate (the rate to synthesize correct product mRNA) and the transcription effectiveness (the ratio of the effective transcription rate to the effective transcription initiation rate) are both influenced by polymerase stalling events. So far, no theoretical model has been given to discuss the gene transcription process including polymerase stalling. In this study, based on the totally asymmetric simple exclusion process, the transcription process including polymerase stalling is analyzed theoretically. The dependence of the effective transcription rate, effective transcription initiation rate, and transcription effectiveness on the transcription initiation rate, termination rate, as well as the backtracking rate, bypass rate, and detachment (degradation) rate when stalling, are discussed in detail. The results showed that backtracking restart after polymerase stalling is an ideal mechanism to increase both the effective transcription rate and the transcription effectiveness. Without backtracking, detachment of stalled polymerase can also help to increase the effective transcription rate and transcription effectiveness. Generally, the increase of the bypass rate of the stalled polymerase will lead to the decrease of the effective transcription rate and transcription effectiveness. However, when both detachment rate and backtracking rate of the stalled polymerase vanish, the effective transcription rate may also be increased by the bypass mechanism.

  16. Molecular envelope and atomic model of an anti-terminated glyQS T-box regulator in complex with tRNAGly. (United States)

    Chetnani, Bhaskar; Mondragón, Alfonso


    A T-box regulator or riboswitch actively monitors the levels of charged/uncharged tRNA and participates in amino acid homeostasis by regulating genes involved in their utilization or biosynthesis. It has an aptamer domain for cognate tRNA recognition and an expression platform to sense the charge state and modulate gene expression. These two conserved domains are connected by a variable linker that harbors additional secondary structural elements, such as Stem III. The structural basis for specific tRNA binding is known, but the structural basis for charge sensing and the role of other elements remains elusive. To gain new structural insights on the T-box mechanism, a molecular envelope was calculated from small angle X-ray scattering data for the Bacillus subtilis glyQS T-box riboswitch in complex with an uncharged tRNAGly. A structural model of an anti-terminated glyQS T-box in complex with its cognate tRNAGly was derived based on the molecular envelope. It shows the location and relative orientation of various secondary structural elements. The model was validated by comparing the envelopes of the wild-type complex and two variants. The structural model suggests that in addition to a possible regulatory role, Stem III could aid in preferential stabilization of the T-box anti-terminated state allowing read-through of regulated genes. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  17. DksA guards elongating RNA polymerase against ribosome-stalling-induced arrest. (United States)

    Zhang, Yan; Mooney, Rachel A; Grass, Jeffrey A; Sivaramakrishnan, Priya; Herman, Christophe; Landick, Robert; Wang, Jue D


    In bacteria, translation-transcription coupling inhibits RNA polymerase (RNAP) stalling. We present evidence suggesting that, upon amino acid starvation, inactive ribosomes promote rather than inhibit RNAP stalling. We developed an algorithm to evaluate genome-wide polymerase progression independently of local noise and used it to reveal that the transcription factor DksA inhibits promoter-proximal pausing and increases RNAP elongation when uncoupled from translation by depletion of charged tRNAs. DksA has minimal effect on RNAP elongation in vitro and on untranslated RNAs in vivo. In these cases, transcripts can form RNA structures that prevent backtracking. Thus, the effect of DksA on transcript elongation may occur primarily upon ribosome slowing/stalling or at promoter-proximal locations that limit the potential for RNA structure. We propose that inactive ribosomes prevent formation of backtrack-blocking mRNA structures and that, in this circumstance, DksA acts as a transcription elongation factor in vivo. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Dynamic Stall in Pitching Airfoils: Aerodynamic Damping and Compressibility Effects (United States)

    Corke, Thomas C.; Thomas, Flint O.


    Dynamic stall is an incredibly rich fluid dynamics problem that manifests itself on an airfoil during rapid, transient motion in which the angle of incidence surpasses the static stall limit. It is an important element of many manmade and natural flyers, including helicopters and supermaneuverable aircraft, and low-Reynolds number flapping-wing birds and insects. The fluid dynamic attributes that accompany dynamic stall include an eruption of vorticity that organizes into a well-defined dynamic stall vortex and massive excursions in aerodynamic loads that can couple with the airfoil structural dynamics. The dynamic stall process is highly sensitive to surface roughness that can influence turbulent transition and to local compressibility effects that occur at free-stream Mach numbers that are otherwise incompressible. Under some conditions, dynamic stall can result in negative aerodynamic damping that leads to limit-cycle growth of structural vibrations and rapid mechanical failure. The mechanisms leading to negative damping have been a principal interest of recent experiments and analysis. Computational fluid dynamic simulations and low-order models have not been good predictors so far. Large-eddy simulation could be a viable approach although it remains computationally intensive. The topic is technologically important owing to the desire to develop next-generation rotorcraft that employ adaptive rotor dynamic stall control.

  19. Development of a minimal saponin vaccine adjuvant based on QS-21 (United States)

    Fernández-Tejada, Alberto; Chea, Eric K.; George, Constantine; Pillarsetty, Nagavarakishore; Gardner, Jeffrey R.; Livingston, Philip O.; Ragupathi, Govind; Lewis, Jason S.; Tan, Derek S.; Gin, David Y.


    Adjuvants are materials added to vaccines to enhance the immunological response to an antigen. QS-21 is a natural product adjuvant under investigation in numerous vaccine clinical trials, but its use is constrained by scarcity, toxicity, instability and an enigmatic molecular mechanism of action. Herein we describe the development of a minimal QS-21 analogue that decouples adjuvant activity from toxicity and provides a powerful platform for mechanistic investigations. We found that the entire branched trisaccharide domain of QS-21 is dispensable for adjuvant activity and that the C4-aldehyde substituent, previously proposed to bind covalently to an unknown cellular target, is also not required. Biodistribution studies revealed that active adjuvants were retained preferentially at the injection site and the nearest draining lymph nodes compared with the attenuated variants. Overall, these studies have yielded critical insights into saponin structure-function relationships, provided practical synthetic access to non-toxic adjuvants, and established a platform for detailed mechanistic studies.

  20. Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer. (United States)

    Ragupathi, Govind; Gardner, Jeffrey R; Livingston, Philip O; Gin, David Y


    One of the most widely used and potent immunological adjuvants is a mixture of soluble triterpene glycosides purified from the soap bark tree (Quillaja saponaria). Despite challenges in production, quality control, stability and toxicity, the QS-21 fraction from this extract has exhibited exceptional adjuvant properties for a range of antigens. It possesses an ability to augment clinically significant antibody and T-cell responses to vaccine antigens against a variety of infectious diseases, degenerative disorders and cancers. The recent synthesis of active molecules of QS-21 has provided a robust method to produce this leading vaccine adjuvant in high purity as well as to produce novel synthetic QS-21 congeners designed to induce increased immune responsiveness and decreased toxicity.

  1. The crowded magnetosphere of the post common envelope binary QS Virginis


    Parsons, S. G.; Hill, C. A.; Marsh, T. R.; Gansicke, B. T.; Watson, C. A.; Steeghs, D.; Dhillon, V. S.; Littlefair, S. P.; Copperwheat, C. M.; Schreiber, M. R.; Zorotovic, M.


    We present high-speed photometry and high-resolution spectroscopy of the eclipsing post-common-envelope binary QS Virginis (QS Vir). Our Ultraviolet and Visual Echelle Spectrograph (UVES) spectra span multiple orbits over more than a year and reveal the presence of several large prominences passing in front of both the M star and its white dwarf companion, allowing us to triangulate their positions. Despite showing small variations on a time-scale of days, they persist for more than a year an...

  2. Flap motion of helicopter rotors with novel, dynamic stall model

    Directory of Open Access Journals (Sweden)

    Han Wei


    Full Text Available In this paper, a nonlinear flapping equation for large inflow angles and flap angles is established by analyzing the aerodynamics of helicopter blade elements. In order to obtain a generalized flap equation, the Snel stall model was first applied to determine the lift coefficient of the helicopter rotor. A simulation experiment for specific airfoils was then conducted to verify the effectiveness of the Snel stall model as it applies to helicopters. Results show that the model requires no extraneous parameters compared to the traditional stall model and is highly accurate and practically applicable. Based on the model, the relationship between the flapping angle and the angle of attack was analyzed, as well as the advance ratio under the dynamic stall state.

  3. HAWT dynamic stall response asymmetries under yawed flow conditions

    Energy Technology Data Exchange (ETDEWEB)

    Schreck, S.; Robinson, M.; Hand, M.; Simms, D.


    Horizontal axis wind turbines can experience significant time varying aerodynamic loads, potentially causing adverse effects on structures, mechanical components, and power production. As designers attempt lighter and more flexible wind energy machines, greater accuracy and robustness will become even more critical in future aerodynamics models. Aerodynamics modeling advances, in turn, will rely on more thorough comprehension of the three-dimensional, unsteady, vortical flows that dominate wind turbine blade aerodynamics under high load conditions. To experimentally characterize these flows, turbine blade surface pressures were acquired at multiple span locations via the NREL Phase IV Unsteady Aerodynamics Experiment. Surface pressures and associated normal force histories were used to characterize dynamic stall vortex kinematics and normal force amplification. Dynamic stall vortices and normal force amplification were confirmed to occur in response to angle of attack excursions above the static stall threshold. Stall vortices occupied approximately one-half of the blade span and persisted for nearly one-fourth of the blade rotation cycle. Stall vortex convection varied along the blade, resulting in dramatic deformation of the vortex. Presence and deformation of the dynamic stall vortex produced corresponding amplification of normal forces. Analyses revealed consistent alterations to vortex kinematics in response to changes in reduced frequency, span location, and yaw error. Finally, vortex structures and kinematics not previously documented for wind turbine blades were isolated.

  4. 50 CFR 680.41 - Transfer of QS, PQS, IFQ and IPQ. (United States)


    ... application. NMFS will process a request for transfer of crab individual processor quota (IPQ) provided that a... request for transfer of crab quota share (QS) or crab processor quota share (PQS) provided that a paper... community represented. (B) Required attachments to the application. (1) The articles of incorporation under...

  5. Simpson's Paradox and Confounding Factors in University Rankings: A Demonstration Using QS 2011-12 Data (United States)

    Soh, Kay Cheng


    University ranking has become ritualistic in higher education. Ranking results are taken as bona fide by rank users. Ranking systems usually use large data sets from highly heterogeneous universities of varied backgrounds. This poses the problem of Simpson's Paradox and the lurking variables causing it. Using QS 2011-2012 Ranking data, the dual…

  6. Q-S synchronization of the fractional-order unified system

    Indian Academy of Sciences (India)


    Mar 3, 2013 ... 3School of Automation, Beijing Institute of Technology, Beijing 100081,. People's Republic of China. ∗. Corresponding author. E-mail: MS received 29 September 2011; revised 21 September 2012; accepted 8 October 2012. Abstract. Concept of Q-S synchronization for ...

  7. Performance evaluation of the Artus hepatitis C virus QS-RGQ assay. (United States)

    Paba, Pierpaolo; Fabeni, Lavinia; Perno, Carlo Federico; Ciotti, Marco


    Accurate determination of hepatitis C virus RNA level is essential for evaluating the response to antiviral therapy, to determine the duration of treatment, and to predict treatment outcome. Currently, two real-time based polymerase chain reaction assays are used widely to monitor the hepatitis C RNA level: the Abbott RealTime HCV assay and the Cobas Taqman HCV assay. Recently, a third assay has become commercially available: the Artus HCV QS-RGQ assay, which uses the QIAsymphony SP/AS platform for sample preparation and PCR-setup, and the Rotor-Gene Q for amplification and detection. In this study, the performance of the Artus HCV QS-RGQ assay was tested on 105 plasma samples and compared to that of the Cobas Taqman HCV assay. Linear regression analysis showed a good agreement between the two assays. A slightly better sensitivity was observed with the Cobas Taqman assay, while higher hepatitis C viral RNA levels were measured by the Artus HCV QS-RGQ assay in samples positive for hepatitis C genotypes 4. Taken together, the data suggest that the Artus HCV QS-RGQ assay is useful in a diagnostic setting. The combination with the versatile QIAsymphony SP/AS system may represent a major advantage for clinical virological laboratories aiming at optimizing their workflow. Copyright © 2011 Elsevier B.V. All rights reserved.

  8. Pseudoscalar-photon mixing and the large scale alignment of QsO ...

    Indian Academy of Sciences (India)

    physics pp. 679-682. Pseudoscalar-photon mixing and the large scale alignment of QsO optical polarizations. PANKAJ JAIN, sUKANTA PANDA and s sARALA. Physics Department, Indian Institute of Technology, Kanpur 208 016, India. Abstract. We review the observation of large scale alignment of QSO optical polariza-.

  9. Meta-Analysis on Randomized Controlled Trials of Vaccines with QS-21 or ISCOMATRIX Adjuvant : Safety and Tolerability

    NARCIS (Netherlands)

    Bigaeva, Emilia; Doorn, Eva van; Liu, Heng; Hak, Eelko


    BACKGROUND AND OBJECTIVES: QS-21 shows in vitro hemolytic effect and causes side effects in vivo. New saponin adjuvant formulations with better toxicity profiles are needed. This study aims to evaluate the safety and tolerability of QS-21 and the improved saponin adjuvants (ISCOM, ISCOMATRIX and

  10. Synthetic studies of complex immunostimulants from Quillaja saponaria: synthesis of the potent clinical immunoadjuvant QS-21Aapi. (United States)

    Kim, Yong-Jae; Wang, Pengfei; Navarro-Villalobos, Mauricio; Rohde, Bridget D; Derryberry, JohnMark; Gin, David Y


    QS-21 is one of the most promising new adjuvants for immune response potentiation and dose-sparing in vaccine therapy given its exceedingly high level of potency and its favorable toxicity profile. Melanoma, breast cancer, small cell lung cancer, prostate cancer, HIV-1, and malaria are among the numerous maladies targeted in more than 80 recent and ongoing vaccine therapy clinical trials involving QS-21 as a critical adjuvant component for immune response augmentation. QS-21 is a natural product immunostimulatory adjuvant, eliciting both T-cell- and antibody-mediated immune responses with microgram doses. Herein is reported the synthesis of QS-21A(api) in a highly modular strategy, applying novel glycosylation methodologies to a convergent construction of the potent saponin immunostimulant. The chemical synthesis of QS-21 offers unique opportunities to probe its mode of biological action through the preparation of otherwise unattainable nonnatural saponin analogues.

  11. Is Social Licence A Licence To Stall?

    Directory of Open Access Journals (Sweden)

    Mark Lowey


    Full Text Available The School of Public Policy at the University of Calgary organized a one-day symposium on Oct. 8, 2014 in Calgary, as part of the School’s TransCanada Corporation Energy Policy and Regulatory Frameworks Program. The symposium was titled “Is Social License a License to Stall?” Held at the Hotel Arts, the event attracted a full-capacity audience of about 110 people, including representatives from industry, government and environmental non-government organizations. The symposium included four moderated panel sessions and a keynote speaker at lunch. The School of Public Policy set the framework for discussion at the Calgary symposium with the following description: Canada’s regulators act in the public interest to review energy and infrastructure project applications. Regulators are guided by procedural fairness and follow a transparent application, review and hearing process with data filings and sworn testimony. But that’s changing. “Social license” is a relatively new term, which some interests are using to create a different standard for the approval of projects — especially energy projects. According to social license advocates, projects must meet often ill-defined requirements set up by non-governmental organizations, local residents or other interests — a new hurdle for project approval, but without the rigour and rule of law of a regulator. Is social license a meaningful addition to the regulatory process, or is it being used as a constantly moving goal-post designed to slow down regulatory processes, delay project implementation, frustrate energy infrastructure expansion and even enrich those advocates who promote it as a new model? This paper summarises the discussion and the themes that emerged throughout the day. Most notably, panellists concluded that “social licence” is a real and significant issue that presents both an opportunity and a problem, not only for regulators but for all parties involved in the

  12. Dynamic Stall Characteristics of Drooped Leading Edge Airfoils (United States)

    Sankar, Lakshmi N.; Sahin, Mehmet; Gopal, Naveen


    Helicopters in high-speed forward flight usually experience large regions of dynamic stall over the retreating side of the rotor disk. The rapid variations in the lift and pitching moments associated with the stall process can result in vibratory loads, and can cause fatigue and failure of pitch links. In some instances, the large time lag between the aerodynamic forces and the blade motion can trigger stall flutter. A number of techniques for the alleviation of dynamic stall have been proposed and studied by researchers. Passive and active control techniques have both been explored. Passive techniques include the use of high solidity rotors that reduce the lift coefficients of individual blades, leading edge slots and leading edge slats. Active control techniques include steady and unsteady blowing, and dynamically deformable leading edge (DDLE) airfoils. Considerable amount of experimental and numerical data has been collected on the effectiveness of these concepts. One concept that has not received as much attention is the drooped-leading edge airfoil idea. It has been observed in wind tunnel studies and flight tests that drooped leading edge airfoils can have a milder dynamic stall, with a significantly milder load hysteresis. Drooped leading edge airfoils may not, however, be suitable at other conditions, e.g. in hover, or in transonic flow. Work needs to be done on the analysis and design of drooped leading edge airfoils for efficient operation in a variety of flight regimes (hover, dynamic stall, and transonic flow). One concept that is worthy of investigation is the dynamically drooping airfoil, where the leading edge shape is changed roughly once-per-rev to mitigate the dynamic stall.

  13. The Dynamics of SecM-Induced Translational Stalling

    Directory of Open Access Journals (Sweden)

    Albert Tsai


    Full Text Available SecM is an E. coli secretion monitor capable of stalling translation on the prokaryotic ribosome without cofactors. Biochemical and structural studies have demonstrated that the SecM nascent chain interacts with the 50S subunit exit tunnel to inhibit peptide bond formation. However, the timescales and pathways of stalling on an mRNA remain undefined. To provide a dynamic mechanism for stalling, we directly tracked the dynamics of elongation on ribosomes translating the SecM stall sequence (FSTPVWISQAQGIRAGP using single-molecule fluorescence techniques. Within 1 min, three peptide-ribosome interactions work cooperatively over the last five codons of the SecM sequence, leading to severely impaired elongation rates beginning from the terminal proline and lasting four codons. Our results suggest that stalling is tightly linked to the dynamics of elongation and underscore the roles that the exit tunnel and nascent chain play in controlling fundamental steps in translation.

  14. The dynamics of SecM-induced translational stalling. (United States)

    Tsai, Albert; Kornberg, Guy; Johansson, Magnus; Chen, Jin; Puglisi, Joseph D


    SecM is an E. coli secretion monitor capable of stalling translation on the prokaryotic ribosome without cofactors. Biochemical and structural studies have demonstrated that the SecM nascent chain interacts with the 50S subunit exit tunnel to inhibit peptide bond formation. However, the timescales and pathways of stalling on an mRNA remain undefined. To provide a dynamic mechanism for stalling, we directly tracked the dynamics of elongation on ribosomes translating the SecM stall sequence (FSTPVWISQAQGIRAGP) using single-molecule fluorescence techniques. Within 1 min, three peptide-ribosome interactions work cooperatively over the last five codons of the SecM sequence, leading to severely impaired elongation rates beginning from the terminal proline and lasting four codons. Our results suggest that stalling is tightly linked to the dynamics of elongation and underscore the roles that the exit tunnel and nascent chain play in controlling fundamental steps in translation. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  15. A Comparative Study of Three Methodologies for Modeling Dynamic Stall (United States)

    Sankar, L.; Rhee, M.; Tung, C.; ZibiBailly, J.; LeBalleur, J. C.; Blaise, D.; Rouzaud, O.


    During the past two decades, there has been an increased reliance on the use of computational fluid dynamics methods for modeling rotors in high speed forward flight. Computational methods are being developed for modeling the shock induced loads on the advancing side, first-principles based modeling of the trailing wake evolution, and for retreating blade stall. The retreating blade dynamic stall problem has received particular attention, because the large variations in lift and pitching moments encountered in dynamic stall can lead to blade vibrations and pitch link fatigue. Restricting to aerodynamics, the numerical prediction of dynamic stall is still a complex and challenging CFD problem, that, even in two dimensions at low speed, gathers the major difficulties of aerodynamics, such as the grid resolution requirements for the viscous phenomena at leading-edge bubbles or in mixing-layers, the bias of the numerical viscosity, and the major difficulties of the physical modeling, such as the turbulence models, the transition models, whose both determinant influences, already present in static maximal-lift or stall computations, are emphasized by the dynamic aspect of the phenomena.

  16. Time Accurate Unsteady Simulation of the Stall Inception Process in the Compression System of a US Army Helicopter Gas Turbine Engine

    National Research Council Canada - National Science Library

    Hathaway, Michael D; Herrick, Greg; Chen, Jenping; Webster, Robert


    .... Improved understanding of the stall inception process and how stall control technologies mitigate such will provide compressors with increased tolerance to stall, thereby expanding the operational...

  17. PTEN Regulates DNA Replication Progression and Stalled Fork Recovery (United States)

    He, Jinxue; Kang, Xi; Yin, Yuxin; Chao, K.S. Clifford; Shen, Wen H.


    Faithful DNA replication is a cornerstone of genomic integrity. PTEN plays multiple roles in genome protection and tumor suppression. Here we report on the importance of PTEN in DNA replication. PTEN depletion leads to impairment of replication progression and stalled fork recovery, indicating an elevation of endogenous replication stress. Exogenous replication inhibition aggravates replication-originated DNA lesions without inducing S-phase arrest in cells lacking PTEN, representing replication stress tolerance. Our analysis reveals the physical association of PTEN with DNA replication forks and PTEN-dependent recruitment of Rad51. PTEN deletion results in Rad51 dissociation from replication forks. Stalled replication forks in Pten null cells can be reactivated by ectopic Rad51 or PTEN, the latter facilitating chromatin loading of Rad51. These data highlight the interplay of PTEN with Rad51 in promoting stalled fork restart. We propose that loss of PTEN may initiate a replication stress cascade that progressively deteriorates through the cell cycle. PMID:26158445

  18. Active Suppression of Rotating Stall Inception with Distributed Jet Actuation

    Directory of Open Access Journals (Sweden)

    Huu Duc Vo


    Full Text Available An analytical and experimental investigation of the effectiveness of full-span distributed jet actuation for active suppression of long length-scale rotating stall inception is carried out. Detailed modeling and experimental verification highlight the important effects of mass addition, discrete injectors, and feedback dynamics, which may be overlooked in preliminary theoretical studies of active control with jet injection. A model of the compression system incorporating nonideal injection and feedback dynamics is verified with forced response measurements to predict the right trends in the movement of the critical pole associated with the stall precursor. Active control experiments with proportional feedback control show that the predicted stall precursors are suppressed to give a 5.5% range extension in compressor flow coefficient. In addition, results suggest that the proposed model could be used to design a more sophisticated controller to further improve performance while reducing actuator bandwidth requirements.

  19. Stall Recovery Guidance Algorithms Based on Constrained Control Approaches (United States)

    Stepanyan, Vahram; Krishnakumar, Kalmanje; Kaneshige, John; Acosta, Diana


    Aircraft loss-of-control, in particular approach to stall or fully developed stall, is a major factor contributing to aircraft safety risks, which emphasizes the need to develop algorithms that are capable of assisting the pilots to identify the problem and providing guidance to recover the aircraft. In this paper we present several stall recovery guidance algorithms, which are implemented in the background without interfering with flight control system and altering the pilot's actions. They are using input and state constrained control methods to generate guidance signals, which are provided to the pilot in the form of visual cues. It is the pilot's decision to follow these signals. The algorithms are validated in the pilot-in-the loop medium fidelity simulation experiment.

  20. Enhancing Immunogenicity of Cancer Vaccines: QS-21 as an Immune Adjuvant (United States)

    Gin, David Y.; Slovin, Susan F.


    Saponins comprise a class of plant natural products that incorporate a lipophilic terpenoid core, to which is appended one or more carbohydrate residues. They are amphiphilic molecules and often exhibit toxic biological profiles, likely as a result of their roles as vital components in protective coatings to defend against phytopathogen infection and insect predation. The most notable of adjuvant-active saponins investigated for vaccine development come from the Chilean Soapbark Tree, Quillaja saponaria (i.e., QS). More than 30 years ago, semi-purified extracts (i.e., Quil A) from the cortex of Quillaja saponaria were found to be highly effective as adjuvants in veterinary vaccines. However, due to significant and variable toxicity effects, Quil A was not deemed appropriate for human vaccines. More refined purification methods have led to multiple fractions which are derived from the original plant extract. As such, QS-21 to date appears to be one of the more scientifically interesting and robust adjuvants in use in vaccinology. The role of QS-21 as an adjuvant for use in a variety of cancer vaccine trials and its comparison to other adjuvants is discussed in this review. PMID:25473385


    Directory of Open Access Journals (Sweden)



    Full Text Available Thermoregulatory responses of horses subjected to summer-time road transport and stall confinement were investigated in this study. Six mature geldings were transported 168 km in a 4-horse trailer and were monitored while tethered in their stalls, on alternate days. Core body temperature (GT demonstrated negligible response during transport, but GT following transport was higher than GT for non-transport. GT tended to increase with increased temperature humidity index (THI. THI within the trailer was greatest for positions near the front, and was influenced by daily weather which varied over experiment days from heat stress conditions to moderate discomfort.

  2. A dynamic stall model for airfoils with deformable trailing edges

    DEFF Research Database (Denmark)

    Andersen, Peter Bjørn; Gaunaa, Mac; Bak, Christian


    The present work contains an extension of the Beddoes-Leishman-type dynamic stall model. In this work, a deformable trailing-edge flap has been added to the dynamic stall model. The model predicts the unsteady aerodynamic forces and moments on an airfoil section undergoing arbitrary motion in hea...... for the attached flow region and Hansen et al. The model is compared qualitatively to wind tunnel measurements of a Riso/ B1-18 blade section equipped with deformable trailing-edge flap devices in the form of piezoelectric devices. Copyright © 2009 John Wiley & Sons, Ltd....

  3. Regulation of bacterial gene expression by ribosome stalling and rescuing. (United States)

    Jin, Yongxin; Jin, Shouguang; Wu, Weihui


    Ribosome is responsible for protein synthesis and is able to monitor the sequence and structure of the nascent peptide. Such ability plays an important role in determining overall gene expression profile of the bacteria through ribosome stalling and rescuing. In this review, we briefly summarize our current understanding of the regulation of gene expression through ribosome stalling and rescuing in bacteria, as well as mechanisms that modulate ribosome activity. Understanding the mechanisms of how bacteria modulate ribosome activity will provide not only fundamental insights into bacterial gene regulation, but also new candidate targets for the development of novel antimicrobial agents.

  4. A dynamic stall model for airfoils with deformable trailing edges

    DEFF Research Database (Denmark)

    Andersen, Peter Bjørn; Gaunaa, Mac; Bak, Dan Christian


    on an airfoil section undergoing arbitrary motion in heave, lead-lag, pitch, Trailing Edge (TE) flapping. In the linear region, the model reduces to the inviscid model of Gaunaa [4], which includes the aerodynamic effect of a thin airfoil with a deformable camberline in inviscid flow. Therefore, the proposed......The present work contains an extension of the Beddoes-Leishman (B-L) type dynamic stall model, as described by Hansen et al. [7]. In this work a Deformable Trailing Edge Geometry (DTEG) has been added to the dynamic stall model. The model predicts the unsteady aerodynamic forces and moments...

  5. Dynamic Stall Flow Control Through the Use of a Novel Plasma Based Actuator Technology, Phase I (United States)

    National Aeronautics and Space Administration — Lynntech proposes a novel flow control methodology for airfoils undergoing dynamic stall. Dynamic stall refers to an aerodynamic phenomenon that is experienced by...

  6. Unsteady Double Wake Model for the Simulation of Stalled Airfoils

    DEFF Research Database (Denmark)

    Ramos García, Néstor; Cayron, Antoine; Sørensen, Jens Nørkær


    separation and its dynamics. In this paper, the calculated integral forces have been successfully validated against wind tunnel measurements for the FFA-W3-211 airfoil. Furthermore, the computed highly unsteady flow field is analyzed in detail for a set of angles of attack ranging from light to deep stall...

  7. Dynamic Characteristics of Rotating Stall in Mixed Flow Pump

    Directory of Open Access Journals (Sweden)

    Xiaojun Li


    Full Text Available Rotating stall, a phenomenon that causes flow instabilities and pressure hysteresis by propagating at some fraction of the impeller rotational speed, can occur in centrifugal impellers, mixed impellers, radial diffusers, or axial diffusers. Despite considerable efforts devoted to the study of rotating stall in pumps, the mechanics of this phenomenon are not sufficiently understood. The propagation mechanism and onset of rotating stall are not only affected by inlet flow but also by outlet flow as well as the pressure gradient in the flow passage. As such, the complexity of these concepts is not covered by the classical explanation. To bridge this research gap, the current study investigated prerotation generated at the upstream of the impeller, leakage flow at the tip clearance between the casing and the impeller, and strong reserve flow at the inlet of the diffuser. Understanding these areas will clarify the origin of the positive slope of the head-flow performance curve for a mixed flow pump. Nonuniform pressure distribution and adverse pressure gradient were also introduced to evaluate the onset and development of rotating stall within the diffuser.

  8. The Mechanical Impact of Aerodynamic Stall on Tunnel Ventilation Fans

    Directory of Open Access Journals (Sweden)

    A. G. Sheard


    Full Text Available This paper describes work aimed at establishing the ability of a tunnel ventilation fan to operate without risk of mechanical failure in the event of aerodynamic stall. The research establishes the aerodynamic characteristics of a typical tunnel ventilation fan when operated in both stable and stalled aerodynamic conditions, with and without an anti-stall stabilisation ring, with and without a “nonstalling” blade angle and at full, half, and one quarter design speed. It also measures the fan’s peak stress, thus facilitating an analysis of the implications of the experimental results for mechanical design methodology. The paper concludes by presenting three different strategies for tunnel ventilation fan selection in applications where the selected fan will most likely stall. The first strategy selects a fan with a low-blade angle that is nonstalling. The second strategy selects a fan with a high-pressure developing capability. The third strategy selects a fan with a fitted stabilisation ring. Tunnel ventilation system designers each have their favoured fan selection strategy. However, all three strategies can produce system designs within which a tunnel ventilation fan performs reliably in-service. The paper considers the advantages and disadvantages of each selection strategy and considered the strengths and weaknesses of each.


    Directory of Open Access Journals (Sweden)

    Sabina Angrecka


    The obtained results allowed us to identify optimal orientation of barns and to suggest the simplest technical measures to protect sidewall stalls from solar heat gain deleterious to cows. The model analysis of stall shading demonstrated that extension of barn eaves to 1 m on the southern side reduced the insolation of stalls over even up to 90% of their area.

  10. A CFD Database for Airfoils and Wings at Post-Stall Angles of Attack (United States)

    Petrilli, Justin; Paul, Ryan; Gopalarathnam, Ashok; Frink, Neal T.


    This paper presents selected results from an ongoing effort to develop an aerodynamic database from Reynolds-Averaged Navier-Stokes (RANS) computational analysis of airfoils and wings at stall and post-stall angles of attack. The data obtained from this effort will be used for validation and refinement of a low-order post-stall prediction method developed at NCSU, and to fill existing gaps in high angle of attack data in the literature. Such data could have potential applications in post-stall flight dynamics, helicopter aerodynamics and wind turbine aerodynamics. An overview of the NASA TetrUSS CFD package used for the RANS computational approach is presented. Detailed results for three airfoils are presented to compare their stall and post-stall behavior. The results for finite wings at stall and post-stall conditions focus on the effects of taper-ratio and sweep angle, with particular attention to whether the sectional flows can be approximated using two-dimensional flow over a stalled airfoil. While this approximation seems reasonable for unswept wings even at post-stall conditions, significant spanwise flow on stalled swept wings preclude the use of two-dimensional data to model sectional flows on swept wings. Thus, further effort is needed in low-order aerodynamic modeling of swept wings at stalled conditions.

  11. Tannin-rich fraction from Terminalia catappa inhibits quorum sensing (QS) in Chromobacterium violaceum and the QS-controlled biofilm maturation and LasA staphylolytic activity in Pseudomonas aeruginosa. (United States)

    Taganna, Joemar C; Quanico, Jusal P; Perono, Rose Marie G; Amor, Evangeline C; Rivera, Windell L


    The study aimed to test the activity of Terminalia catappa L. against bacterial quorum sensing (QS) in order to provide a potential scientific basis for the traditional use of leaf extracts of this plant as an antiseptic. The anti-QS activity of the methanolic leaf extract of Terminalia catappa was detected through the inhibition of the QS-controlled violacein pigment production in Chromobacterium violaceum. Fractions resulting from size-exclusion chromatography were assayed. The most active fraction was characterized through qualitative phytochemical detection methods. The effect of this fraction on known QS-controlled phenotypes in test strains was assessed. The fraction with the highest activity (labeled as TCF12) was characterized to be tannin-rich. It specifically inhibited QS-controlled violacein production in Chromobacterium violaceum with 50% reduction achieved at 62.5 μg mL(-1) without significantly affecting growth up to about 962 μg mL(-1). The assessment of its effects on LasA activity of Pseudomonas aeruginosa ATCC 10145 found that the production of this virulence determinant is reduced in a concentration dependent manner with about 50% reduction at 62.5 μg mL(-1). Furthermore, it was found that TCF12 was able to inhibit the maturation of biofilms of Pseudomonas aeruginosa, a phenotype that has also been known to be QS-regulated. Therefore, tannin-rich components of Terminalia catappa leaves are able to inhibit certain phenotypic expression of QS in the test strains used. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  12. Simulation Model of an Active-stall Fixed-speed Wind Turbine Controller

    DEFF Research Database (Denmark)

    Jauch, Clemens; Hansen, Anca D.; Soerensen, Poul


    This paper describes an active-stall wind turbine controller. The objective is to develop a general model of an active stall controller in order to simulate the operation of grid connected active stall wind turbines. The active stall turbine concept and its control strategies are presented...... and evaluated by simulations. The presented controller is described for continuous operation under all wind speeds from start-up wind speed to shut down wind speed. Due to its parametric implementation it is general i.e. it can represent different active stall wind turbine controllers and can be implemented...

  13. Simulation model of an active-stall fixed-speed wind turbine controller

    Energy Technology Data Exchange (ETDEWEB)

    Jauch, C.; Hansen, A.D.; Sorensen, P.; Blaabjerg, F.


    This paper describes an active-stall wind turbine controller. The objective is to develop a general model of an active stall controller in order to simulate the operation of grid connected active stall wind turbines. The active stall turbine concept and its control strategies are presented and evaluated by simulations. The presented controller is described for continuous operation under all wind speeds from start-up wind speed to shut down wind speed. Due to its parametric implementation it is general i. e. it can represent different active stall wind turbine controllers and can be implemented in different simulation tools. (author)

  14. Flow and Noise Characteristics of Centrifugal Fan under Different Stall Conditions

    Directory of Open Access Journals (Sweden)

    Lei Zhang


    Full Text Available An implicit, time-accurate 3D Reynolds-averaged Navier-Stokes (RANS solver is used to simulate the rotating stall phenomenon in a centrifugal fan. The goal of the present work is to shed light on the flow field and particularly the aerodynamic noise at different stall conditions. Aerodynamic characteristics, frequency domain characteristics, and the contours of sound power level under two different stall conditions are discussed in this paper. The results show that, with the decrease of valve opening, the amplitude of full pressure and flow fluctuations tends to be larger and the stall frequency remains the same. The flow field analysis indicates that the area occupied by stall cells expands with the decrease of flow rate. The noise calculation based on the simulation underlines the role of vortex noise after the occurrence of rotating stall, showing that the high noise area rotates along with the stall cell in the circumferential direction.

  15. DYNSTALL: Subroutine package with a dynamic stall model

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerck, Anders [Aeronautical Research Inst. of Sweden, Bromma (Sweden)


    A subroutine package, called DYNSTALL, for the calculation of 2D unsteady airfoil aerodynamics is described. The subroutines are written in FORTRAN. DYNSTALL is basically an implementation of the Beddoes-Leishman dynamic stall model. This model is a semi-empirical model for dynamic stall. It includes, however, also models for attached flow unsteady aerodynamics. It is complete in the sense that it treats attached flow as well as separated flow. Semi-empirical means that the model relies on empirically determined constants. Semi because the constants are constants in equations with some physical interpretation. It requires the input of 2D airfoil aerodynamic data via tables as function of angle of attack. The method is intended for use in an aeroelastic code with the aerodynamics solved by blade/element method. DYNSTALL was written to work for any 2D angles of attack relative to the airfoil, e.g. flow from the rear of an airfoil.

  16. Development of Improved Vaccine Adjuvants Based on the Saponin Natural Product QS-21 through Chemical Synthesis. (United States)

    Fernández-Tejada, Alberto; Tan, Derek S; Gin, David Y


    Vaccines based on molecular subunit antigens are increasingly being investigated due to their improved safety and more precise targeting compared to classical whole-pathogen vaccines. However, subunit vaccines are inherently less immunogenic; thus, coadministration of an adjuvant to increase the immunogenicity of the antigen is often necessary to elicit a potent immune response. QS-21, an immunostimulatory saponin natural product, has been used as an adjuvant in conjunction with various vaccines in numerous clinical trials, but suffers from several inherent liabilities, including scarcity, chemical instability, and dose-limiting toxicity. Moreover, little is known about its mechanism of action. Over a decade-long effort, beginning at the University of Illinois at Urbana-Champaign and continuing at the Memorial Sloan Kettering Cancer Center (MSKCC), the group of Prof. David Y. Gin accomplished the total synthesis of QS-21 and developed a practical semisynthetic approach to novel variants that overcome the liabilities of the natural product. First, semisynthetic QS-21 variants were designed with stable amide linkages in the acyl chain domain that exhibited comparable in vivo adjuvant activity and lower toxicity than the natural product. Further modifications in the acyl chain domain and truncation of the linear tetrasaccharide domain led to identification of a trisaccharide variant with a simple carboxylic acid side chain that retained potent adjuvant activity, albeit with reemergence of toxicity. Conversely, an acyl chain analogue terminating in a free amine was inactive but enabled chemoselective functionalization with radiolabeled and fluorescent tags, yielding adjuvant-active saponin probes that, unlike inactive congeners, accumulated in the lymph nodes in vaccinated mice and internalized into dendritic cells. Subtle variations in length, stereochemistry, and conformational flexibility around the central glycosidic linkage provided QS-21 variants with adjuvant

  17. Systemic Synthesis Questions [SSynQs] as Tools to Help Students to Build Their Cognitive Structures in a Systemic Manner (United States)

    Hrin, Tamara N.; Fahmy, Ameen F. M.; Segedinac, Mirjana D.; Milenković, Dušica D.


    Many studies dedicated to the teaching and learning of organic chemistry courses have emphasized that high school students have shown significant difficulties in mastering the concepts of this discipline. Therefore, the aim of our study was to help students to overcome these difficulties by applying systemic synthesis questions, [SSynQs], as the instructional method in our intervention. This work shows that students from the group exposed to the new teaching method achieved higher scores on final testing than students from the control group, who were taught by the traditional method, when students' achievements in conventional, linear questions [LQs] and in [SSynQs] were studied. These results were followed by observation of lower levels of mental effort by students from the intervention group, and higher levels of mental effort in the control group, invested during solving both types of questions. This correlation between achievement and mental effort resulted in high instructional efficiency for the applied method in the intervention group, [SSynQs], and low instructional efficiency for the traditional teaching and learning method applied in the control group. A systemic triangular relation between achievement, mental effort, and instructional efficiency, established by each group and gender, emphasized that the application of [SSynQs] was more suited to female students than for male students because of [SSynQs] characteristics as teaching and learning tools and because of learning style and ability differences between genders.

  18. Study and Control of a Radial Vaned Diffuser Stall

    Directory of Open Access Journals (Sweden)

    Aurélien Marsan


    Full Text Available The aim of the present study is to evaluate the efficiency of a boundary layer suction technique in case of a centrifugal compressor stage in order to extend its stable operating range. First, an analysis of the flow pattern within the radial vaned diffuser is presented. It highlights the stall of the diffuser vanes when reaching a low massflow. A boundary layer separation in the hub-suction side corner grows when decreasing the massflow from the nominal operating point to the surge and finally leads to a massive stall. An aspiration strategy is investigated in order to control the stall. The suction slot is put in the vicinity of the saddle that originates the main separating skin-friction line, identified thanks to the analysis of the skin-friction pattern. Several aspiration massflow rates are tested, and two different modelings of the aspiration are evaluated. Finally, an efficient control is reached with a removal of only 0,1% of the global massflow and leads—from a steady-state calculations point of view—to an increase by 40% of the compressor operating range extent.

  19. Vorticity Transport on a Flexible Wing in Stall Flutter (United States)

    Akkala, James; Buchholz, James; Farnsworth, John; McLaughlin, Thomas


    The circulation budget within dynamic stall vortices was investigated on a flexible NACA 0018 wing model of aspect ratio 6 undergoing stall flutter. The wing had an initial angle of attack of 6 degrees, Reynolds number of 1 . 5 ×105 and large-amplitude, primarily torsional, limit cycle oscillations were observed at a reduced frequency of k = πfc / U = 0 . 1 . Phase-locked stereo PIV measurements were obtained at multiple chordwise planes around the 62.5% and 75% spanwise locations to characterize the flow field within thin volumetric regions over the suction surface. Transient surface pressure measurements were used to estimate boundary vorticity flux. Recent analyses on plunging and rotating wings indicates that the magnitude of the pressure-gradient-driven boundary flux of secondary vorticity is a significant fraction of the magnitude of the convective flux from the separated leading-edge shear layer, suggesting that the secondary vorticity plays a significant role in regulating the strength of the primary vortex. This phenomenon is examined in the present case, and the physical mechanisms governing the growth and evolution of the dynamic stall vortices are explored. This work was supported by the Air Force Office of Scientific Research through the Flow Interactions and Control Program monitored by Dr. Douglas Smith, and through the 2014 AFOSR/ASEE Summer Faculty Fellowship Program (JA and JB).

  20. Simulasi Numerik Dynamic Stall Pada Airfoil Yang Berosilasi

    Directory of Open Access Journals (Sweden)

    Galih S.T.A. Bangga


    Full Text Available Kebutuhan analisa pada sudu helikopter, kompresor, kincir angin dan struktur streamline lainya yang beroperasi pada angle of attack yang tinggi dan melibatkan instationary effects yang disebut dynamic stall menjadi semakin penting. Fenomena ini ditandai dengan naiknya dynamic lift melewati static lift maksimum pada critical static stall angle, vortex yang terbentuk pada leading edge mengakibatkan naiknya suction contribution yang kemudian terkonveksi sepanjang permukaan hingga mencapai trailling edge diikuti terbentuknya trailling edge vortex yang menunjukkan terjadinya lift stall. Fenomena ini sangat berbahaya terhadap struktur airfoil itu sendiri. Secara umum, beban fatique yang ditimbulkan oleh adanya efek histerisis karena fluktuasi gaya lift akibat induksi vibrasi lebih besar dibandingkan kondisi statis. Simulasi numerik dilakukan secara 2D dengan menggunakan profil Boeing-Vertol V23010-1.58 pada α0 = 14.92°. Standard-kω dan SST-kω digunakan sebagai URANS turbulence modelling. Model osilasi dari airfoil disusun dalam suatu user defined function (UDF. Gerakan meshing beserta airfoil diakomodasi dengan menggunakan dynamic mesh approach. Simulasi numerik menunjukkan bahwa, model SST-kω menunjukkan performa yang lebih baik dibandingkan dengan Standard-kω. Fenomena travelling vortex yang terjadi mampu ditangkap dengan baik, meski pada angle of attack yang tinggi URANS turbulence model gagal memprediksikan fenomena yang terjadi karena dominasi efek 3D.

  1. Prediction of dynamic loads and induced vibrations in stall

    Energy Technology Data Exchange (ETDEWEB)

    Thirstrup Petersen, J.; Aagaard Madsen, H. [Risoe National Lab. (Denmark); Bjoerck, A. [Aeronautical Research Inst. of Sweden (Sweden); Enevoldsen, P. [Bonus Energy A/S (Denmark); Oeye, S. [The Technical Univ. of Denmark (Denmark); Ganander, H. [Teknikgruppen AB (Sweden); Winkelaar, D. [Netherlands Energy Research Foundation (Netherlands)


    Results from research in an EC Joule-III project and from national projects are presented. The objectives are improvement of design methods for stall regulated wind turbines with emphasis on stall induced vibrations and dynamic stall. The primary concern is limitation of the edgewise vibrations in the fundamental blade natural mode shape, which have caused trouble on modern wind turbines of approximate size 500 kW nominal power and 40 m rotor diameter. A theoretical study of quasi-steady aerodynamics confirms that the vibrations are driven basically by energy supplied from the aerodynamic forces during stalled operation. This energy exchange is equivalent to negative aerodynamic damping. The theoretical approach identifies the main parameters controlling the phenomenon. These parameters describe the steady and the dynamic airfoil characteristics, the overall aerodynamic layout of the blade, e.g. chord length and twist, the structural properties of the blade, e.g. structural damping and properties controlling the resulting vibration direction. Furthermore, full aeroelastic calculations and comparison with measurements show that the properties of the supporting structure, i.e. the main shaft, the nacelle and the tower, are important, as the global vibration of the rotor on its support may exchange energy with the blade vibration, when the blade natural frequency is close to one of the frequencies of the coupled rotor tilt-yaw mode shapes, usually denoted the global rotor whirl frequencies. It is confirmed that the influence of changing the primary design parameters can be determined by use of qualified aeroelastic calculations. Presented design guidelines therefore build on both the simple quasi-steady models, which can be used for the preliminary choice of the design variables mentioned above, and on full aeroelastic calculations. The aeroelastic calculations refine the design basis and should be used for choosing the final design variables and for final

  2. Wider stall space affects behavior, lesion scores, and productivity of gestating sows. (United States)

    Salak-Johnson, J L; DeDecker, A E; Levitin, H A; McGarry, B M


    Limited space allowance within the standard gestation stall is an important welfare concern because it restricts the ability of the sow to make postural adjustments and hinders her ability to perform natural behaviors. Therefore, we evaluated the impacts of increasing stall space and/or providing sows the freedom to access a small pen area on sow well-being using multiple welfare metrics. A total of 96 primi- and multiparous crossbred sows were randomly assigned in groups of 4 sows/treatment across 8 replicates to 1 of 3 stall treatments (TRT): standard stall (CTL; dimensions: 61 by 216 cm), width-adjustable stall (flex stall [FLX]; dimensions: adjustable width of 56 to 79 cm by 216 cm), or an individual walk-in/lock-in stall with access to a small communal open-pen area at the rear of the stall (free-access stall [FAS]; dimensions: 69 by 226 cm). Lesion scores, behavior, and immune and productivity traits were measured at various gestational days throughout the study. Total lesion scores were greatest for sows in FAS and least for sows in FLX ( pregnancy progressed, lesion scores increased among sows in CTL ( postural behaviors and sham chew behavior were affected by TRT ( changes in postural behaviors, lesion severity scores, and other sow traits. Moreover, compromised welfare measures found among sows in various stall environments may be partly attributed to the specific constraints of each stall system such as restricted stall space in CTL, insufficient floor space in the open-pen area of the FAS system, and gate design of the FLX (e.g., direction of bars and feeder space). These results also indicate that parity and gestational day are additional factors that may exacerbate the effects of restricted stall space or insufficient pen space, further compromising sow well-being.

  3. Meta-Analysis on Randomized Controlled Trials of Vaccines with QS-21 or ISCOMATRIX Adjuvant: Safety and Tolerability (United States)

    Bigaeva, Emilia; van Doorn, Eva; Liu, Heng; Hak, Eelko


    Background and Objectives QS-21 shows in vitro hemolytic effect and causes side effects in vivo. New saponin adjuvant formulations with better toxicity profiles are needed. This study aims to evaluate the safety and tolerability of QS-21 and the improved saponin adjuvants (ISCOM, ISCOMATRIX and Matrix-M™) from vaccine trials. Methods A systematic literature search was conducted from MEDLINE, EMBASE, Cochrane library and We selected for the meta-analysis randomized controlled trials (RCTs) of vaccines adjuvanted with QS-21, ISCOM, ISCOMATRIX or Matrix-M™, which included a placebo control group and reported safety outcomes. Pooled risk ratios (RRs) and their 95% confidence intervals (CIs) were calculated using a random-effects model. Jadad scale was used to assess the study quality. Results Nine RCTs were eligible for the meta-analysis: six trials on QS-21-adjuvanted vaccines and three trials on ISCOMATRIX-adjuvanted, with 907 patients in total. There were no studies on ISCOM or Matrix-M™ adjuvanted vaccines matching the inclusion criteria. Meta-analysis identified an increased risk for diarrhea in patients receiving QS21-adjuvanted vaccines (RR 2.55, 95% CI 1.04–6.24). No increase in the incidence of the reported systemic AEs was observed for ISCOMATRIX-adjuvanted vaccines. QS-21- and ISCOMATRIX-adjuvanted vaccines caused a significantly higher incidence of injection site pain (RR 4.11, 95% CI 1.10–15.35 and RR 2.55, 95% CI 1.41–4.59, respectively). ISCOMATRIX-adjuvanted vaccines also increased the incidence of injection site swelling (RR 3.43, 95% CI 1.08–10.97). Conclusions Our findings suggest that vaccines adjuvanted with either QS-21 or ISCOMATRIX posed no specific safety concern. Furthermore, our results indicate that the use of ISCOMATRIX enables a better systemic tolerability profile when compared to the use of QS-21. However, no better local tolerance was observed for ISCOMATRIX-adjuvanted vaccines in immunized non

  4. Examining obligations to society for QS Stars best ranked universities in social responsibility

    Directory of Open Access Journals (Sweden)

    Păunescu Carmen


    Full Text Available Developing the local, regional, even national communities is often central to a university’s mission. This is a two-way process and both society and university itself should benefit from this collaboration. Universities around the world have been in the past decades required to leave their ivory tower and to become more involved in addressing the needs of the society and thus more relevant for the communities which they serve. They are expected to take a leadership role in implementation of the required change by contributing to community development through knowledge, innovations, skills and jobs. By taking a leading role in society and continuously innovating, universities will support communities with achieving a sustainable growth and therefore will contribute to increasing the well-being of society at large. The current paper aims to assess the university obligations to society by analyzing 27 universities around the world best ranked in social responsibility according to QS Stars University Rating 2016. In the paper, we discuss the extent to which different attributes of the university social responsibility are reflected among the initiatives and projects run by the universities included in the study. Also, an exploratory factor analysis was employed to identify underlying variables that explain the pattern of correlations between university social responsibility initiatives. Following the QS Stars methodology, the dimensions used to evaluate social responsibility of sampled universities included: community investment and development, social work and disaster relief, regional human capital development, and environmental impact. The results show that the level of involvement in social responsibility actions is high for all the universities included in the study. Also, the types of initiatives vary in terms of nature, intensity and impact for each one of the dimensions analyzed. Our research findings offer useful insights for both

  5. Precautions against axial fan stall in reactor building to Tianwan NPP

    International Nuclear Information System (INIS)

    Liu Chunlong; Pei Junmin


    The paper introduces the mechanism and harm of rotating stall of axial fans, analyzes the necessity for prevention against axial fan stall in reactor building of Tianwan NPP, introduces the precautions, and then makes an assessment on anti-stall effect of flow separators. It can provide reference for model-selection or reconstruction of similar fans in power stations, and for operation and maintenance of axial fans. (authors)

  6. Comparison of Different Stall Conditions in Axial Flow Compressor Using Analytic Wavelet Transform

    Directory of Open Access Journals (Sweden)

    Arshad Ali


    Full Text Available The rotating stall inception data analysis using Analytic Wavelet Transform (AWT in a low-speed axial compressor was presented in the authors’ previous studies [1], [2]. These studies focused on the detection of instability inception in an axial flow compressor when it enters into the instability regime due to the modal type of stall perturbation. In this paper, the effectiveness of AWT is further studied by applying it under different testing conditions. In order to examine the results of AWT on highly sampled data, at first, the stall data were acquired at a high sampling frequency and the results were compared with the conventional filtered signals. Secondly, the AWT analysis of stall data was carried out for the condition when compressor experienced a spike type rotating stall disturbance. The stall inception information obtained from the AWT analysis was then compared with the commonly used stall detection techniques. The results show that AWT is equally beneficial for the diagnostic of compressor instability regardless of the data sampling rate and represents an outstanding ability to detect stall disturbance irrespective of the type of stall precursor, i.e. the modal wave or spike.

  7. Enhancing BEM simulations of a stalled wind turbine using a 3D correction model (United States)

    Bangga, Galih; Hutomo, Go; Syawitri, Taurista; Kusumadewi, Tri; Oktavia, Winda; Sabila, Ahmad; Setiadi, Herlambang; Faisal, Muhamad; Hendranata, Yongki; Lastomo, Dwi; Putra, Louis; Kristiadi, Stefanus; Bumi, Ilmi


    Nowadays wind turbine rotors are usually employed with pitch control mechanisms to avoid deep stall conditions. Despite that, wind turbines often operate under pitch fault situation causing massive flow separation to occur. Pure Blade Element Momentum (BEM) approaches are not designed for this situation and inaccurate load predictions are already expected. In the present studies, BEM predictions are improved through the inclusion of a stall delay model for a wind turbine rotor operating under pitch fault situation of -2.3° towards stall. The accuracy of the stall delay model is assessed by comparing the results with available Computational Fluid Dynamics (CFD) simulations data.

  8. Numerical simulation of the RISOe1-airfoil dynamic stall

    Energy Technology Data Exchange (ETDEWEB)

    Bertagnolio, F.; Soerensen, N. [Risoe National Lab., Wind Energy and Atmospheric Physics Dept., Roskilde (Denmark)


    In this paper we are concerned with the numerical computation of the dynamic stall that occur in the viscous flowfield over an airfoil. These results are compared to experimental data that were obtained with the new designed RISOe1-airfoil, both for a motionless airfoil and for a pitching motion. Moreover, we present some numerical computations of the plunging and lead-lag motions. We also investigate the possibility of using the pitching motion to simulate the plunging and lead-lag situations. (au)

  9. El departamento musical Disney : las Silly Symphonies y Carl Stalling


    Duarte del Moral, Marina


    La historia de la animación tiene un nombre propio: Walt Disney. Gracias a su experimentación en diversos campos de esta materia, Disney consigue desarrollar la animación y su universo de una forma perseverante y continua, adaptándose a los diversos cambios producidos desde el nacimiento de ésta, reinventando una y otra vez el sector y añadiendo su toque mágico a la personalidad de cada personaje y cada obra. En este camino no está solo gracias al trabajo de genios como Carl Stalling, que apo...

  10. FBH1 Catalyzes Regression of Stalled Replication Forks

    DEFF Research Database (Denmark)

    Fugger, Kasper; Mistrik, Martin; Neelsen, Kai J


    DNA replication fork perturbation is a major challenge to the maintenance of genome integrity. It has been suggested that processing of stalled forks might involve fork regression, in which the fork reverses and the two nascent DNA strands anneal. Here, we show that FBH1 catalyzes regression......, is required for early phosphorylation of ATM substrates such as CHK2 and CtIP as well as hyperphosphorylation of RPA. These phosphorylations occur prior to apparent DNA double-strand break formation. Furthermore, FBH1-dependent signaling promotes checkpoint control and preserves genome integrity. We propose...

  11. Autonomous control of metabolic state by a quorum sensing (QS)-mediated regulator for bisabolene production in engineered E. coli

    DEFF Research Database (Denmark)

    Kim, Eun-Mi; Min Woo, Han; Tian, Tian


    I-luxR genes, and four variants of the Response plasmid, which carry bisabolene producing pathway genes under the control of the PluxI promoter, were designed for optimization of bisabolene production. Furthermore, a chromosome-integrated QS strain was engineered with the best combination of Sensor...

  12. The Times Higher Education Supplement and Quacquarelli Symonds (THES - QS) World University Rankings: New Developments in Ranking Methodology (United States)

    Sowter, Ben


    This paper presents key new developments in the THES - QS World University Rankings in 2007, related to enhancements to the "Peer Review", "Data Collection" and "Statistical Aggregation" utilised in this ranking as well as discussing the decision to utilise Full-Time Equivalent (FTE) figures for personnel statistics. Indicator correlation is also…

  13. Adjuvant ganglioside GM2-KLH/QS-21 vaccination versus observation after resection of primary tumor > 1.5 mm in patients with stage II melanoma

    DEFF Research Database (Denmark)

    Eggermont, Alexander M M; Suciu, Stefan; Rutkowski, Piotr


    The GM2 ganglioside is an antigen expressed in the majority of melanomas. The GM2-KLH/QS-21 vaccine induces high immunoglobulin M (IgM) and IgG antibody responses. The EORTC 18961 trial compared the efficacy of GM2-KLH/QS-21 vaccination versus observation....

  14. The FFA dynamic stall model. The Beddoes-Leishman dynamic stall model modified for lead-lag oscillations

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerck, A. [FFA, The Aeronautical Research Institute of Sweden, Bromma (Sweden)


    For calculations of the dynamics of wind turbines the inclusion of a dynamic stall model is necessary in order to obtain reliable results at high winds. For blade vibrations in the lead-lag motion the velocity relative to the blade will vary in time. In the present paper modifications to the Beddoes-Leishman model is presented in order to improve the model for calculations of cases with a varying relative velocity. Comparisons with measurement are also shown and the influence on the calculated aerodynamic damping by the modifications are investigated. (au)

  15. Ingestive behavior of lambs confined in individual and group stalls. (United States)

    Filho, A Eustáquio; Carvalho, G G P; Pires, A J V; Silva, R R; Santos, P E F; Murta, R M; Pereira, F M


    The experiment was conducted to evaluate the ingestive behavior of lambs confined in individual and group stalls. We used thirty-four lambs in their growing phase, aged an average of three months, with mean initial live weight of 17.8±5.2 kg. They were allotted in a completely randomized design with 24 animals kept in individual stalls and 10 animals confined as a group. The experiment lasted for a total of 74 days, and the first 14 days were dedicated to the animals' adaption to the management, facilities and diets. The data collection period lasted 60 days, divided into three 20-d periods for the behavior evaluation. The animals were subjected to five days of visual observation during the experiment period, by the quantification of 24 h a day, with evaluations on the 15th day of each period and an interim evaluation consisting of two consecutive days on the 30th and 31st day of the experiment. The animals confined as a group consumed less (pbehavior.

  16. A.C. Plasma Anemometer for Axial Compressor Stall Warning (United States)

    Matlis, Eric; Cameron, Joshua; Morris, Scott; Corke, Thomas


    Compressor sections of turbo jet engines are subject to stall and surge as a result of flow instabilities that occur upstream of the compressor rotor. One of the instability modes that contributes to compressor surge is the so-called `spike' mode of stall inception. It has been shown that this mode of instability can be predicted before onset by performing real-time statistical auto-correlation measurements of the blade-passing pressure characteristic at the mid-chord location of the rotor. These measurements are performed with pressure sensors or hot-wires that are too fragile for a full-scale compressor. We have developed a sensor that can survive the vibration and temperatures of a full-scale rig while providing the bandwidth necessary to resolve the blade passage signature required by this coherence technique. This sensor, called the Plasma Anemometer, provides high-bandwith point measurements of velocity or pressure fluctuations with unparalleled mechanical robustness and resistance to vibration and thermal effects.

  17. Evaluating Classroom Interaction with the iPad®: An Updated Stalling's Tool (United States)

    MacKinnon, Gregory; Schep, Lourens; Borden, Lisa Lunney; Murray-Orr, Anne; Orr, Jeff; MacKinnon, Paula


    A large study of classrooms in the Caribbean context necessitated the use of a validated classroom observation tool. In practice, the paper-version Stalling's instrument (Stallings & Kaskowitz 1974) presented specific challenges with respect to (a) facile data collection and (b) qualitative observations of classrooms. In response to these…

  18. Simulation of Entropy Generation under Stall Conditions in a Centrifugal Fan

    Directory of Open Access Journals (Sweden)

    Lei Zhang


    Full Text Available Rotating stalls are generally the first instability met in turbomachinery, before surges. This 3D phenomenon is characterized by one or more stalled flow cells which rotate at a fraction of the impeller speed. The goal of the present work is to shed some light on the entropy generation in a centrifugal fan under rotating stall conditions. A numerical simulation of entropy generation is carried out with the ANSYS Fluent software which solves the Navier-Stokes equations and user defined function (UDF. The entropy generation characteristics in the centrifugal fan for five typical conditions are presented and discussed, involving the design condition, conditions on occurrence and development of stall inception, the rotating stall conditions with two throttle coefficients. The results show that the entropy generation increases after the occurrence of stall inception. The high entropy generation areas move along the circumferential and axial directions, and finally merge into one stall cell. The entropy generation rate during circumferential propagation of the stall cell is also discussed, showing that the entropy generation history is similar to sine curves in impeller and volute, and the volute tongue has a great influence on entropy generation in the centrifugal fan.

  19. Konsep al-Mujrim dalam QS. al-Kahf [18]: 47-49

    Directory of Open Access Journals (Sweden)

    Agil Bahsoan


    Full Text Available Many people think that sin is merely doing what is prohibited and forbidden only. They forget that the first of iniquity to Allâh is leaving what was ordered, as when God commanded the devil prostrate to Adam, but Satan disobey His commands. This is the iniquity of Satan for the first time. Some scholars argue that all iniquity is a great sin. It looks like the scholars look of the Greatness of Allah Almighty and Exalted who disobeyed, so that even if the actual insubordination to his small, it still saw iniquity in him as a sin. In addition, many people do not know that in addition to the sin associated with the act limb zâhir as sin is born of the hands, feet, eyes, tongue, genitals and so there is also a sin that binds to the liver that cannot be seen by the eye but can be felt the impact, which is meant here is iniquity liver, such as cocky, riya, arrogant and so forth. These hearts are intrinsically more dangerous lawlessness of iniquity was born. Therefore this article will review the sin, the types of sins, causes the sinner based interpretation tahlîlî and mawdû‘î in QS. al-Kahf (18 47-49.

  20. Optimal parameters for the FFA-Beddoes dynamic stall model

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerck, A.; Mert, M. [FFA, The Aeronautical Research Institute of Sweden, Bromma (Sweden); Madsen, H.A. [Risoe National Lab., Roskilde (Denmark)


    Unsteady aerodynamic effects, like dynamic stall, must be considered in calculation of dynamic forces for wind turbines. Models incorporated in aero-elastic programs are of semi-empirical nature. Resulting aerodynamic forces therefore depend on values used for the semi-empiricial parameters. In this paper a study of finding appropriate parameters to use with the Beddoes-Leishman model is discussed. Minimisation of the `tracking error` between results from 2D wind tunnel tests and simulation with the model is used to find optimum values for the parameters. The resulting optimum parameters show a large variation from case to case. Using these different sets of optimum parameters in the calculation of blade vibrations, give rise to quite different predictions of aerodynamic damping which is discussed. (au)

  1. Proposed Chevron Tengiz venture stalls amid Soviet political squabble

    International Nuclear Information System (INIS)



    This paper reports on the status of foreign investment in Soviet oil and gas joint ventures which has reached a critical juncture. Just as the U.S. is considering granting most favored nation trade status to the U.S.S.R., the joint venture petroleum deal seen as the litmus test for such deals-Chevron Corp.'s proposed addition of supergiant Tengiz oil field to its Caspian Sea joint venture-has stalled amid controversy. Unconfirmed reports from Soviet officials and other foreign joint venture participants in the U.S.S.R. have Chevron pulling out of the long negotiated, multibillion dollar project after the Soviets rejected the company's terms. Chevron, however, insists the project is still alive

  2. Q-S synchronization in 3D Henon-like map and generalized Henon map via a scalar controller

    International Nuclear Information System (INIS)

    Yan Zhenya


    In this Letter, a generalized, systematic and automatic backstepping scheme is developed to investigate the Q-S synchronization of two identical 3a discrete-time dynamical systems and two different 3D discrete-time dynamical systems. With the aid of symbolic-numeric computation, we use the proposed scheme to illustrate chaos synchronization between two identical 3D generalized Henon map and Q-S synchronization between two different 3D generalized Henon map and Henon-like map via a scalar controller, respectively. Moreover numerical simulations are used to verify the effectiveness of the proposed scheme. In addition, the scheme can be also applied to investigate the tracking problem in the discrete-time systems and to generate automatically the scalar controller in computer with the aid of symbolic-numeric computation


    Energy Technology Data Exchange (ETDEWEB)

    Zasche, P.; Juryšek, J.; Nemravová, J.; Wolf, M.; Korčáková, D. [Astronomical Institute, Charles University in Prague, Faculty of Mathematics and Physics, CZ-180 00, Praha 8, V Holešovičkách 2 (Czech Republic); Uhlař, R. [Private Observatory, Pohoří 71, CZ-254 01, Jílové u Prahy (Czech Republic); Svoboda, P. [Private Observatory, Výpustky 5, CZ-614 00, Brno (Czech Republic); Hoňková, K. [Variable Star and Exoplanet Section of Czech Astronomical Society, Vsetínská 941/78, CZ-757 01, Valašské Meziříčí (Czech Republic); Mašek, M.; Prouza, M. [Institute of Physics, The Czech Academy of Sciences, Na Slovance 1999/2, CZ-182 21, Praha (Czech Republic); Čechura, J.; Šlechta, M., E-mail: [Astronomical Institute, The Czech Academy of Sciences, CZ-251 65, Ondřejov (Czech Republic)


    Eclipsing binaries remain crucial objects for our understanding of the universe. In particular, those that are components of multiple systems can help us solve the problem of the formation of these systems. Analysis of the radial velocities together with the light curve produced for the first time precise physical parameters of the components of the multiple systems V773 Cas, QS Aql, and BR Ind. Their visual orbits were also analyzed, which resulted in slightly improved orbital elements. What is typical for all these systems is that their most dominant source is the third distant component. The system V773 Cas consists of two similar G1-2V stars revolving in a circular orbit and a more distant component of the A3V type. Additionally, the improved value of parallax was calculated to be 17.6 mas. Analysis of QS Aql resulted in the following: the inner eclipsing pair is composed of B6V and F1V stars, and the third component is of about the B6 spectral type. The outer orbit has high eccentricity of about 0.95, and observations near its upcoming periastron passage between the years 2038 and 2040 are of high importance. Also, the parallax of the system was derived to be about 2.89 mas, moving the star much closer to the Sun than originally assumed. The system BR Ind was found to be a quadruple star consisting of two eclipsing K dwarfs orbiting each other with a period of 1.786 days; the distant component is a single-lined spectroscopic binary with an orbital period of about 6 days. Both pairs are moving around each other on their 148 year orbit.

  4. Analysis of Low Speed Stall Aerodynamics of a Swept Wing with Laminar Flow Glove (United States)

    Bui, Trong T.


    Reynolds-Averaged Navier-Stokes (RANS) computational fluid dynamics (CFD) analysis was conducted to study the low-speed stall aerodynamics of a GIII aircraft's swept wing modified with a laminar-flow wing glove. The stall aerodynamics of the gloved wing were analyzed and compared with the unmodified wing for the flight speed of 120 knots and altitude of 2300 ft above mean sea level (MSL). The Star-CCM+ polyhedral unstructured CFD code was first validated for wing stall predictions using the wing-body geometry from the First American Institute of Aeronautics and Astronautics (AIAA) CFD High-Lift Prediction Workshop. It was found that the Star-CCM+ CFD code can produce results that are within the scattering of other CFD codes considered at the workshop. In particular, the Star-CCM+ CFD code was able to predict wing stall for the AIAA wing-body geometry to within 1 degree of angle of attack as compared to benchmark wind-tunnel test data. Current results show that the addition of the laminar-flow wing glove causes the gloved wing to stall much earlier than the unmodified wing. Furthermore, the gloved wing has a different stall characteristic than the clean wing, with no sharp lift drop-off at stall for the gloved wing.

  5. Analysis of Low-Speed Stall Aerodynamics of a Swept Wing with Laminar-Flow Glove (United States)

    Bui, Trong T.


    Reynolds-Averaged Navier-Stokes (RANS) computational fluid dynamics (CFD) analysis was conducted to study the low-speed stall aerodynamics of a GIII aircraft's swept wing modified with a laminar-flow wing glove. The stall aerodynamics of the gloved wing were analyzed and compared with the unmodified wing for the flight speed of 120 knots and altitude of 2300 ft above mean sea level (MSL). The Star-CCM+ polyhedral unstructured CFD code was first validated for wing stall predictions using the wing-body geometry from the First American Institute of Aeronautics and Astronautics (AIAA) CFD High-Lift Prediction Workshop. It was found that the Star-CCM+ CFD code can produce results that are within the scattering of other CFD codes considered at the workshop. In particular, the Star-CCM+ CFD code was able to predict wing stall for the AIAA wing-body geometry to within 1 degree of angle of attack as compared to benchmark wind-tunnel test data. Current results show that the addition of the laminar-flow wing glove causes the gloved wing to stall much earlier than the unmodified wing. Furthermore, the gloved wing has a different stall characteristic than the clean wing, with no sharp lift drop-off at stall for the gloved wing.

  6. Investigating Stall Flutter using a DS model-An application for HAWTs

    International Nuclear Information System (INIS)

    Nichols, James; Haans, Wouter; Witcher, David; Attorni, Andrea


    As wind turbine blades become larger there is a tendency for the blade torsional stiffness to reduce, producing the possibility of dynamic instability at moderate windspeeds. While linearised methods can assess the envelope of allowable blade properties for avoiding classical flutter with attached flow aerodynamics, wind turbine aerofoils can experience stalled flow. Therefore, it is necessary to explore the possible effects of stall-flutter on blade stability. This paper aims to address methods for judging the stability of blade designs during both attached flow and stalled flow behaviour. This paper covers the following areas: i) Attached flow model A Beddoes-Leishman indicial model is presented and the choice of coefficients is explained in the context of Theodorsen's theory for flat-plate aerofoils and experimental results by Beddoes and Leishman. Special attention is given to the differing dynamic behaviour of the pitching moment due to flapping motion, pitching motion and dynamically varying inflow. (ii) Classical flutter analysis The time domain attached flow model is verified against a linear flutter analysis by comparing time domain results for a 3D model of a representative multi-megawatt turbine blade, varying the position of the centre of mass along the chord. The results show agreement to within 6% for a range of flutter onset speeds. (iii) Dynamic stall model On entering the stalled region, damping of torsional motion of an aerofoil section can become negative. A dynamic stall model which encompasses the effects of trailing edge separation and leading edge vortex detachment is presented and validated against published experimental data. (iv) Stall flutter The resulting time domain model is used in simulations validating the prediction of reduced flutter onset for stalled aerofoils. Representative stalled conditions for a multi-megawatt wind turbine blade are investigated to assess the possible reduction in flutter speed. A maximum reduction of 17

  7. Analysis of Low-Speed Stall Aerodynamics of a Business Jets Wing Using STAR-CCM+ (United States)

    Bui, Trong


    Reynolds-Averaged Navier-Stokes (RANS) computational fluid dynamics (CFD) analysis was conducted: to study the low-speed stall aerodynamics of a GIII aircrafts swept wing modified with (1) a laminar-flow wing glove, or (2) a seamless flap. The stall aerodynamics of these two different wing configurations were analyzed and compared with the unmodified baseline wing for low-speed flight. The Star-CCM+ polyhedral unstructured CFD code was first validated for wing stall predictions using the wing-body geometry from the First AIAA CFD High-Lift Prediction Workshop.

  8. Stalling HIV through social marketing: prospects in Pakistan. (United States)

    Husain, Sara; Shaikh, Babar T


    Over the last two decades HIV/AIDS has evolved from a series of interesting case-reports to a growing epidemic that threatens the entire world. It is feared to cause devastation among large pockets of populations and may roll back more than thirty years of public health achievements. This killer disease has been more amenable to behavioral change than by provision of curative services and attempts are being made to educate the public about this threat. Various techniques of promotion have been tried through out the world including television dramas/soaps, mass media and school curricula. Social marketing is an evolving strategy used to influence human behavior and choices. By using the principles of marketing and promoting behavior as a product, social marketers attempt to understand the dynamics of human behaviour and devise messages and products to change, modify, accept or reject unsafe behaviors or practices. Thus, social marketers provide an effective force to combat the spread of HIV and may serve to be invaluable allies in health promotion efforts. In a complex and diversified cultural milieu of Pakistan, social marketing can have a significant impact on health determinants and the conditions that will facilitate the adoption of health-oriented behaviors and practices. This paper gives an account of the elements needed for the success of a health promotion strategy adopted in a developing country and makes a case for social marketing to be adopted as the lead strategy for stalling HIV/AIDS in Pakistan.

  9. Initial design of a stall-controlled wind turbine rotor

    Energy Technology Data Exchange (ETDEWEB)

    Nygaard, T.A. [Inst. for Energiteknikk, Kjeller (Norway)


    A model intended for initial design of stall-controlled wind turbine rotors is described. The user specifies relative radial position of an arbitrary number of airfoil sections, referring to a data file containing lift-and drag curves. The data file is on the same format as used in the commercial blade-element code BLADES-/2/, where lift- and drag coefficients are interpolated from tables as function of Reynolds number, relative thickness and angle of attack. The user can set constraints on a selection of the following: Maximum power; Maximum thrust in operation; Maximum root bending moment in operation; Extreme root bending moment, parked rotor; Tip speed; Upper and lower bounds on optimisation variables. The optimisation variables can be selected from: Blade radius; Rotational speed; Chord and twist at an arbitrary number of radial positions. The user can chose linear chord distribution and a hyperbola-like twist distribution to ensure smooth planform and twist, or cubic spline interpolation for one or both. The aerodynamic model is based on classical strip theory with Prandtl tip loss correction, supplemented by empirical data for high induction factors. (EG)

  10. Cow preference and usage of free stalls compared with an open pack area. (United States)

    Fregonesi, J A; von Keyserlingk, M A G; Weary, D M


    Free-stall housing systems are designed to provide a comfortable and hygienic lying area, but some aspects of stall design may restrict usage by cows. The aim of this study was to compare free-stall housing with a comparable lying area (open pack) without stall partitions. We predicted that cows would spend more time lying down and standing in the bedded area when provided access to an open pack than when in free stalls. We also predicted that cows would spend less time standing outside of the lying area and less time perching with the front 2 hooves in the lying area when using the open pack. Groups (n = 8) of 12 cows each were provided access to either the open pack or stalls. After a 7-d adaptation period, each group was tested sequentially in the 2 treatments for 3 d each. This no-choice phase was followed by an 8-d choice phase during which cows had simultaneous access to both treatments. During the no-choice phase, cows spent more time lying down (13.03 +/- 0.24 vs. 12.48 +/- 0.24 h/d) and standing with all 4 hooves in the bedded area (0.96 +/- 0.12 vs. 0.41 +/- 0.12 h/d) of the open pack than in the stalls. During the choice phase, cows spent more time lying down (7.20 +/- 0.29 vs. 5.86 +/- 0.29 h/d) and standing with all 4 hooves in the bedded area (0.58 +/- 0.07 vs. 0.12 +/- 0.07 h/d) of the open pack than in the stalls. In both the no-choice (1.66 +/- 0.24 vs. 0.55 +/- 0.24 h/d) and choice (0.55 +/- 0.07 vs. 0.29 +/- 0.07 h/d) phases, cows spent more time standing with just 2 hooves in the stalls than in the open pack. In conclusion, cows spent more time lying and standing with all 4 hooves in the bedded open pack than in the stalls. Additionally, cows spent more time standing in the alley and standing with just the front 2 hooves on the bedding in the stalls than in the bedded open pack; increased standing time on wet concrete is a known risk factor for lameness.

  11. Dynamic stall characterization using modal analysis of phase-averaged pressure distributions (United States)

    Harms, Tanner; Nikoueeyan, Pourya; Naughton, Jonathan


    Dynamic stall characterization by means of surface pressure measurements can simplify the time and cost associated with experimental investigation of unsteady airfoil aerodynamics. A unique test capability has been developed at University of Wyoming over the past few years that allows for time and cost efficient measurement of dynamic stall. A variety of rotorcraft and wind turbine airfoils have been tested under a variety of pitch oscillation conditions resulting in a range of dynamic stall behavior. Formation, development and separation of different flow structures are responsible for the complex aerodynamic loading behavior experienced during dynamic stall. These structures have unique signatures on the pressure distribution over the airfoil. This work investigates the statistical behavior of phase-averaged pressure distribution for different types of dynamic stall by means of modal analysis. The use of different modes to identify specific flow structures is being investigated. The use of these modes for different types of dynamic stall can provide a new approach for understanding and categorizing these flows. This work uses airfoil data acquired under Army contract W911W60160C-0021, DOE Grant DE-SC0001261, and a gift from BP Alternative Energy North America, Inc.

  12. High-Speed Experiments on Combustion-Powered Actuation for Dynamic Stall Suppression (United States)

    Matalanis, Claude; Bowles, Patrick; Lorber, Peter; Crittenden, Thomas; Glezer, Ari; Schaeffler, Norman; Min, Byung-Young; Jee, Solkeun; Kuczek, Andrzej; Wake, Brian


    This work documents high-speed wind tunnel experiments conducted on a pitching airfoil equipped with an array of combustion-powered actuators (COMPACT). The main objective of these experiments was to demonstrate the stall-suppression capability of COMPACT on a high-lift rotorcraft airfoil, the VR-12, at relevant Mach numbers. Through dynamic pressure measurements at the airfoil surface it was shown that COMPACT can positively affect the stall behavior of the VR-12 at Mach numbers up to 0.4. Static airfoil results demonstrated 25% and 50% increases in post-stall lift at Mach numbers of 0.4 and 0.3, respectively. Deep dynamic stall results showed cycle-averaged lift coefficient increases up to 11% at Mach 0.4. Furthermore, it was shown that these benefits could be achieved with relatively few pulses during down-stroke and with no need to pre-anticipate the stall event. The flow mechanisms responsible for stall suppression were investigated using particle image velocimetry.

  13. Experimental Investigation of Stall Inception Mechanisms of Low Speed Contra Rotating Axial Flow Fan Stage

    Directory of Open Access Journals (Sweden)

    Tegegn Dejene Toge


    Full Text Available The present paper is an attempt in understanding the stall inception mechanism in a low speed, contra rotating axial flow fan stage, using wavelet transforms. The rotors used in this study have relatively large tip gap (about 3% of the blade span and aspect ratio of 3. The study was carried out near stall and at stall mass flow conditions for different speed ratios of rotor-2 to rotor-1. Unsteady pressure data from the casing wall mounted sensors are used to understand the stall inception mechanism. The wavelet transform clearly indicates that stall inception occurs mainly through long length scale disturbances for both rotors. It also reveals that short length disturbances occur simultaneously or intermittently in the case of rotor-1. The analysis shows the presence of a strong modal disturbance with 25–80% of the rotor frequency in the case of rotor-1 at the stall mass flow for all the speed combinations studied. The most interesting thing observed in the present study is that the frequency amplitude of the disturbance level is very small for both rotors.

  14. ASPEK PEDADOGIS DALAM DAKWAH RASULULLAH SAW: Studi Analitis atas Q.S. Al-Jumu’ah 62: 2

    Directory of Open Access Journals (Sweden)

    Achmad Muchammad


    Full Text Available Kitab suci al-Qur`an menyebutkan bahwa dalam diri Rasulullah terdapat suri tauladan yang baik (QS. Al-Ahzab 33: 21. Sebagai sosok yang dijadikan percontohan, Rasulullah memiliki kapasitas beragam sehingga setiap individu yang bermaksud meneladani beliau dapat menemukan gambaran ideal sesuai kapasitas pribadinya. Salah satu kapasitas yang melekat pada beliau adalah sebagai guru bagi para Sahabatnya. Adapun materi yang disampaikan berwujud wahyu Ilahi yang ditindaklanjuti dengan penjelasan yang dengan sendirinya menjelma menjadi al-Sunnah. Sisi ini menjadi menarik untuk dikaji sebab, sudah jamak diketahui, beliau adalah seorang revolusioner yang sukses dalam membumikan risalah Ilahiah yang diembannya dalam jangka waktu yang amat singkat hanya sekitar 23 tahun. Barangkali tidak berlebihan manakala ada asumsi tentang bagaimana dahsyatnya pola dakwah serta nuansa pendidikan yang digoreskan beliau dalam setiap dakwahnya tersebut sehingga menghasilkan output yang demikian cemerlang, jika diaplikasikan dalam proses belajar mengajar yang selama ini berjalan. Fokus pembahasan akan diarahkan pada QS. Al-Jumu’ah 62: 2 dengan menggunakan pendekatan analitis atau yang biasa disebut metode tahliliy dalam tafsir.

  15. A Method to Predict Compressor Stall in the TF34-100 Turbofan Engine Utilizing Real-Time Performance Data (United States)


    pass turbo –fan engine sensor data to seek its deterioration modelling and prognostics capability. In futurity this will allow for achievement of...preventive maintenance for the TF34-100 jet engine to prevent engine compressor stalls for the A-10 aircraft. Due to their destructive nature, compressor...stalls are a significant concern in axial flow compressor jet engines. A compressor stall is caused by air approaching the compressor blades at an

  16. An archival analysis of stall warning system effectiveness during airborne icing encounters (United States)

    Maris, John Michael

    An archival study was conducted to determine the influence of stall warning system performance on aircrew decision-making outcomes during airborne icing encounters. A Conservative Icing Response Bias (CIRB) model was developed to explain the historical variability in aircrew performance in the face of airframe icing. The model combined Bayes' Theorem with Signal Detection Theory (SDT) concepts to yield testable predictions that were evaluated using a Binary Logistic Regression (BLR) multivariate technique applied to two archives: the NASA Aviation Safety Reporting System (ASRS) incident database, and the National Transportation Safety Board (NTSB) accident databases, both covering the period January 1, 1988 to October 2, 2015. The CIRB model predicted that aircrew would experience more incorrect response outcomes in the face of missed stall warnings than with stall warning False Alarms. These predicted outcomes were observed at high significance levels in the final sample of 132 NASA/NTSB cases. The CIRB model had high sensitivity and specificity, and explained 71.5% (Nagelkerke R2) of the variance of aircrew decision-making outcomes during the icing encounters. The reliability and validity metrics derived from this study suggest indicate that the findings are generalizable to the population of U.S. registered turbine-powered aircraft. These findings suggest that icing-related stall events could be reduced if the incidence of stall warning Misses could be minimized. Observed stall warning Misses stemmed from three principal causes: aerodynamic icing effects, which reduced the stall angle-of-attack (AoA) to below the stall warning calibration threshold; tail stalls, which are not monitored by contemporary protection systems; and icing-induced system issues (such as frozen pitot tubes), which compromised stall warning system effectiveness and airframe envelope protections. Each of these sources of missed stall warnings could be addressed by Aerodynamic Performance

  17. Stall Margin Improvement in a Centrifugal Compressor through Inducer Casing Treatment

    Directory of Open Access Journals (Sweden)

    V. V. N. K. Satish Koyyalamudi


    Full Text Available The increasing trend of high stage pressure ratio with increased aerodynamic loading has led to reduction in stable operating range of centrifugal compressors with stall and surge initiating at relatively higher mass flow rates. The casing treatment technique of stall control is found to be effective in axial compressors, but very limited research work is published on the application of this technique in centrifugal compressors. Present research was aimed to investigate the effect of casing treatment on the performance and stall margin of a high speed, 4 : 1 pressure ratio centrifugal compressor through numerical simulations using ANSYS CFX software. Three casing treatment configurations were developed and incorporated in the shroud over the inducer of the impeller. The predicted performance of baseline compressor (without casing treatment was in good agreement with published experimental data. The compressor with different inducer casing treatment geometries showed varying levels of stall margin improvement, up to a maximum of 18%. While the peak efficiency of the compressor with casing treatment dropped by 0.8%–1% compared to the baseline compressor, the choke mass flow rate was improved by 9.5%, thus enhancing the total stable operating range. The inlet configuration of the casing treatment was found to play an important role in stall margin improvement.

  18. An airloads theory for morphing airfoils in dynamic stall with experimental correlation (United States)

    Ahaus, Loren A.

    Helicopter rotor blades frequently encounter dynamic stall during normal flight conditions, limiting the applicability of classical thin-airfoil theory at large angles of attack. Also, it is evident that because of the largely different conditions on the advancing and retreating sides of the rotor, future rotorcraft may incorporate dynamically morphing airfoils (trailing-edge aps, dynamic camber, dynamic droop, etc.). Reduced-order aerodynamic models are needed for preliminary design and ight simulation. A unified model for predicting the airloads on a morphing airfoil in dynamic stall is presented, consisting of three components. First, a linear airloads theory allows for arbitrary airfoil deformations consistent with a morphing airfoil. Second, to capture the effects of the wake, the airloads theory is coupled to an induced ow model. Third, the overshoot and time delay associated with dynamic stall are modeled by a second-order dynamic filter, along the lines of the ONERA dynamic stall model. This paper presents a unified airloads model that allows arbitrary airfoil morphing with dynamic stall. Correlations with experimental data validate the theory.

  19. A time-varying subjective quality model for mobile streaming videos with stalling events (United States)

    Ghadiyaram, Deepti; Pan, Janice; Bovik, Alan C.


    Over-the-top mobile video streaming is invariably influenced by volatile network conditions which cause playback interruptions (stalling events), thereby impairing users' quality of experience (QoE). Developing models that can accurately predict users' QoE could enable the more efficient design of quality-control protocols for video streaming networks that reduce network operational costs while still delivering high-quality video content to the customers. Existing objective models that predict QoE are based on global video features, such as the number of stall events and their lengths, and are trained and validated on a small pool of ad hoc video datasets, most of which are not publicly available. The model we propose in this work goes beyond previous models as it also accounts for the fundamental effect that a viewer's recent level of satisfaction or dissatisfaction has on their overall viewing experience. In other words, the proposed model accounts for and adapts to the recency, or hysteresis effect caused by a stall event in addition to accounting for the lengths, frequency of occurrence, and the positions of stall events - factors that interact in a complex way to affect a user's QoE. On the recently introduced LIVE-Avvasi Mobile Video Database, which consists of 180 distorted videos of varied content that are afflicted solely with over 25 unique realistic stalling events, we trained and validated our model to accurately predict the QoE, attaining standout QoE prediction performance.

  20. The role of tip clearance in high-speed fan stall

    Energy Technology Data Exchange (ETDEWEB)

    Adamczyk, J.J. (NASA Lewis Research Center, Cleveland, OH (United States)); Celestina, M.L. (Sverdrup Tech., Inc., Cleveland, OH (United States)); Greitzer, E.M. (Massachusetts Institute of Technology, Cambridge, MA (United States))


    A numerical experiment has been carried out to define the near-stall casing endwall flow field of a high-speed fan rotor. The experiment used a simulation code incorporating a simple clearance model, whose calibration is presented. The results of the simulation show that the interaction of the tip leakage vortex and the in-passage shock plays a major role in determining the fan flow range. More specifically, the computations imply that it is the area increase of this vortex as it passes through the in-passage shock that is the source of the blockage associated with stall. In addition, for fans of this type, it is the clearance over the forward portion of the fan blade that controls the flow processes leading to stall.

  1. The role of tip clearance in high-speed fan stall (United States)

    Adamczyk, J. J.; Celestina, M. L.; Greitzer, E. M.


    A numerical experiment has been carried out to define the near-stall casing endwall flowfield of a high-speed fan rotor. The experiment used a simulation code incorporating a simple clearance model, whose calibration is presented. The results of the simulation show that the interaction of the tip leakage vortex and the in-pasage shock plays a major role in determining the fan flow range. More specifically, the computations imply that it is the area increase of this vortex as it passes through the in-passage shock, which is the source of the blockage associated with stall. In addition, for fans of this type, it is the clearance over the forward portion of the fan blade which controls the flow processes leading to stall.

  2. The computation of the post-stall behavior of a circulation controlled airfoil (United States)

    Linton, Samuel W.


    The physics of the circulation controlled airfoil is complex and poorly understood, particularly with regards to jet stall, which is the eventual breakdown of lift augmentation by the jet at some sufficiently high blowing rate. The present paper describes the numerical simulation of stalled and unstalled flows over a two-dimensional circulation controlled airfoil using a fully implicit Navier-Stokes code, and the comparison with experimental results. Mach numbers of 0.3 and 0.5 and jet total to freestream pressure ratios of 1.4 and 1.8 are investigated. The Baldwin-Lomax and k-epsilon turbulence models are used, each modified to include the effect of strong streamline curvature. The numerical solutions of the post-stall circulation controlled airfoil show a highly regular unsteady periodic flowfield. This is the result of an alternation between adverse pressure gradient and shock induced separation of the boundary layer on the airfoil trailing edge.

  3. Effect of summer grazing on welfare of dairy cows reared in mountain tie-stall barns

    Directory of Open Access Journals (Sweden)

    Simonetta Dovier


    Full Text Available Traditional mountain farms have an important economic, social and environmental role. The Alps management system for dairy cows consists of animals kept indoors from autumn to spring, mostly in tie-stalls, and moved to mountain pasture in summer. The aim of our study was to assess the effect of mountain summer grazing on the welfare of dairy cows housed in tie-stall barns. Twenty-four farms were considered. In twelve of them, animals were reared in tie-stalls and moved to mountain pasture for three months in summer; they were visited three times: (i four weeks before grazing during the indoor period in the stall; (ii about three weeks after the start of grazing; and (iii in the stall, in autumn, at least three weeks after returning from grazing. The other twelve farms kept the animals in tie-stalls all year; they were visited once in autumn. Data were collected following a protocol that considers animal-based measures and structure information on the basis of Quality Welfare Consortium® indications. Data allowed the calculation of both the Animal Needs Index score (ANI 35L and an overall assessment of the cows’ welfare obtained from three general aspects: housing, animal’s physical condition, and animal’s behaviour. Summer grazing had a significant positive effect on injuries, lameness and animal’s rising duration but a negative effect on faeces consistency. Moreover, a reduction of tongue playing was observed. The ANI 35L and the overall assessment did not show significant differences linked to summer grazing, which tended to have a positive but temporary effect on animal behaviour.

  4. Prediction of RNA Polymerase II recruitment, elongation and stalling from histone modification data

    DEFF Research Database (Denmark)

    Chen, Yun; Jørgensen, Mette; Kolde, Raivo


    strategies are needed to progress from descriptive annotation of data to quantitative, predictive models. RESULTS: Here, we describe a computational framework which with high accuracy can predict the locations of core promoters, the amount of recruited RNAPII at the promoter, the amount of elongating RNAPII...... of RNAPII stalling. CONCLUSIONS: In this study we introduce a general framework to accurately predict the level of RNAPII recruitment, elongation, stalling and mRNA expression from chromatin signals. The versatility of the method also makes it ideally suited to investigate other genomic data....

  5. Analysis of compressible light dynamic stall flow at transitional Reynolds numbers

    DEFF Research Database (Denmark)

    Dyken, R.D. Van; Ekaterinaris, John A.; Chandrasekhara, M.S.


    Numerical and experimental results of steady and light dynamic stall flow over an oscillating NACA 0012 airfoil at a freestream Mach number of 0.3 and Reynolds number of 0.54 x 10(6) are compared, The experimental observation that dynamic stall is induced from the bursting of a laminar separation...... point is specified suitably and a simple transition length model is incorporated to determine the extent of the laminar separation bubble. The thin-layer approximations of compressible, Reynolds-averaged, Navier-Stokes equations are used for the numerical solution, with an implicit, upwind-biased, third...

  6. The influence of elevated feed stalls on feeding behaviour of lactating dairy cows

    Directory of Open Access Journals (Sweden)

    Barbara Benz


    Full Text Available The performance level of high yielding cows can only be guaranteed by high quality forage and high feed intake. An about 15–20 cm elevated and 160 cm long feed stall with rubber flooring doesn’t only offer undisturbed meals but also a yielding and dry standing surface. In a pilot stable with 130 dairy cows (German Simmental the feeding alley was subsequently equipped with elevated feed stalls. The results show that animals frequented the feeding barn less often while the duration of single meals prolonged. The specific behavioural changes differed depending on milk yield and number of lactation.

  7. Diagnosis of voltage collapse due to induction motor stalling using static analysis

    International Nuclear Information System (INIS)

    Karbalaei, F.; Kalantar, M.; Kazemi, A.


    Induction motor stalling is one of the important reasons for voltage collapse. This paper presents that, for induction motor stalling diagnosis, it is not necessary to use a third or first order dynamic model of induction motors. Instead, a method is presented based on algebraic calculations for which the steady state model of the induction motor considering different kinds of mechanical loads (constant and variable torque) is added to the power flow equations. Simulation results for a simple system confirm the correctness of the proposed method as compared to dynamic simulation results

  8. Power control of a wind farm with active stall wind turbines and AC grid connection

    DEFF Research Database (Denmark)

    Hansen, Anca Daniela; Sørensen, Poul; Iov, Florin

    This paper describes the design of a centralised wind farm controller for a wind farm made-up exclusively of active stall wind turbines with AC grid connection. The overall aim of such controller is to enable the wind farms to provide the best grid support. The designed wind farm control involves...... both the control on wind turbine level as well as the central control on the wind farm level. The ability of active stall wind farms with AC grid connection to regulate the power production to the reference power ordered by the operators is assessed and discussed by means of simulations....

  9. Validation of the Beddoes-Leishman Dynamic Stall Model for Horizontal Axis Wind Turbines using MEXICO data

    NARCIS (Netherlands)

    Pereira, R.; Schepers, G.; Pavel, M.D.


    The aim of this study is to assess the load predicting capability of a classical Beddoes-Leishman dynamic stall model in a horizontal axis wind turbine (HAWT) environment, in the presence of yaw-misalignment. The dynamic stall model was tailored to the HAWT environment, and validated against

  10. The Variation of Universally Acknowledged World-Class Universities (UAWCUs) between 2010 and 2015: An Empirical Study by the Ranks of THEs, QS and ARWU (United States)

    Liu, Lu; Liu, Zhimin


    Due to certainty recognition in ranking systems, the commonly included top 100 universities are regarded as the Universally Acknowledged World-Class Universities (UAWCUs). From three university rankings-THEs, QS and ARWU from 2010 to 2015, the following conclusions can be drawn from this study: Firstly, 56 universities are commonly ranked in the…

  11. Stimulation of local immunity and protection in mice by intramuscular immunization with triple- or double-layered rotavirus particles and QS-21. (United States)

    McNeal, M M; Rae, M N; Conner, M E; Ward, R L


    Based on studies in animal models, parenteral immunization has become recognized as a potential vaccination strategy against rotavirus. Using an adult mouse model, the effects of the saponin adjuvant QS-21 on protection against murine rotavirus (strain EDIM) infection was determined following two intramuscular (i.m.) immunizations with purified EDIM particles including triple-layered (tl) infectious particles, tl particles inactivated with psoralen/UV, and double-layered (dl) inactivated particles. All three particles stimulated large serum rotavirus IgG responses and small amounts of serum rotavirus IgA, but undetectable stool rotavirus IgA. Inclusion of QS-21 during immunization increased the serum responses approximately 2- to 10-fold and also stimulated low levels of stool rotavirus IgA. Protection based on reduced shedding of rotavirus following EDIM challenge was significant (P immunized group and was enhanced (P immunization. Mice immunized with either live or inactivated tl particles and QS-21 were almost fully protected. Furthermore, animals inoculated with dl particles and the adjuvant shed significantly (P = .02) less virus following challenge than mice immunized with inactivated tl particles even though the latter induced measurable titers of neutralizing antibody to EDIM. These results demonstrate significant protection against rotavirus following i.m. immunization with both dl and tl EDIM particles which is consistently enhanced with QS-21.

  12. A stochastic model for the simulation of wind turbine blades in static stall

    DEFF Research Database (Denmark)

    Bertagnolio, Franck; Rasmussen, Flemming; Sørensen, Niels N.


    The aim of this work is to improve aeroelastic simulation codes by accounting for the unsteady aerodynamic forces that a blade experiences in static stall. A model based on a spectral representation of the aerodynamic lift force is defined. The drag and pitching moment are derived using...

  13. Physics of Prestall Propagating Disturbances in Axial Compressors and Their Potential as a Stall Warning Indicator

    Directory of Open Access Journals (Sweden)

    Mario Eck


    Full Text Available Axial compressors in aero engines are prone to suffering a breakdown of orderly flow when operating at the peak of the pressure rise characteristic. The damaging potential of separated flows is why a safe distance has to be left between every possible operating point and an operating point at which stall occurs. During earlier investigations of stall inception mechanisms, a new type of prestall instability has been found. In this study, it could be demonstrated that the prestall instability characterised by discrete flow disturbances can be clearly assigned to the subject of “Rotating Instabilities”. Propagating disturbances are responsible for the rise in blade passing irregularity. If the mass flow is reduced successively, the level of irregularity increases until the prestall condition devolves into rotating stall. The primary objective of the current work is to highlight the basic physics behind these prestall disturbances by complementary experimental and numerical investigations. Before reaching the peak of the pressure rise characteristic flow, disturbances appear as small vortex tubes with one end attached to the casing and the other attached to the suction surface of the rotor blade. These vortex structures arise when the entire tip region is affected by blockage and at the same time the critical rotor incidence is not exceeded in this flow regime. Furthermore, a new stall indicator was developed by applying statistical methods to the unsteady pressure signal measured over the rotor blade tips, thus granting a better control of the safety margin.

  14. Numerical Study on the Acoustic Characteristics of an Axial Fan under Rotating Stall Condition

    Directory of Open Access Journals (Sweden)

    Lei Zhang


    Full Text Available Axial fan is an important piece of equipment in the thermal power plant that provides enough air for combustion of coal. This paper focuses on the aerodynamic noise characteristics of an axial fan in the development from stall inception to stall cells. The aerodynamic noise characteristic of monitoring region in time and frequency domains was simulated employing the large-eddy simulation (LES, with the addition of throttle setting and the Ffowcs Williams-Hawkings (FW-H noise model. The numerical results show that, under the design condition, the acoustic pressure presents regular periodicity along with the time. The noise energy is concentrated with high energy of the fundamental frequency and high order harmonics. During the stall inception stage, the acoustic pressure amplitude starts fluctuating and discrete frequencies are increased significantly in the low frequency; among them, there are three obvious discrete frequencies: 27.66 Hz, 46.10 Hz and 64.55 Hz. On the rotating stall condition, the fluctuation of the acoustic pressure level and amplitude are more serious than that mentioned above. During the whole evolution process, the acoustic pressure peak is difficult to keep stable all the time, and a sudden increase of the peak value at the 34.5th revolution corresponds to the relative velocity’s first sudden increase at the time when the valve coefficient is 0.780.


    The report gives results of emissions measurements carried out at a representative facility (Eljer Plumbingware in Wilson, NC) that manufactures polyester-resin-reinforced shower stalls and bathtubs by spraying styrene-based resins onto molds in vented, open, spray booths. Styren...

  16. 14 CFR 23.203 - Turning flight and accelerated turning stalls. (United States)


    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Turning flight and accelerated turning stalls. 23.203 Section 23.203 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... a 30 degree bank. Reduce speed by steadily and progressively tightening the turn with the elevator...

  17. Power reduction and the radial limit of stall delay in revolving wings of different aspect ratio

    NARCIS (Netherlands)

    Kruyt, J.W.; Heijst, Van G.F.; Altshuler, D.L.; Lentink, David


    Airplanes and helicopters use high aspect ratio wings to reduce the power required to fly, but must operate at low angle of attack to prevent flow separation and stall. Animals capable of slow sustained flight, such as hummingbirds, have low aspect ratio wings and flap their wings at high angle

  18. Vortical structures responsible for delayed stall in an idealized humpback whale flipper model (United States)

    Kim, Heesu; Kim, Jooha; Choi, Haecheon


    In this study, we investigate how the tubercles on the leading edge of an idealized humpback whale flipper model delay the stall. Oil-surface visualization is performed to see the surface flow pattern on the suction surface, and PIV is conducted in several streamwise and crossflow planes at different attack angles (α). Without tubercles, leading edge separation first occurs near the tip region and progresses inboard with increasing α. With tubercles, however, two types of vortical motions are observed at the mid-span. The first is streamwise vortex arrays which are dominant at α 9° , and these structures appear near the trailing edge. These two types of vortical motions delay flow separation at the peak regions of the mid-span, eliminating the spanwise stall progression and resulting in delayed stall. At α = 16° at which the tubercle model stalls, a large-scale streamwise vortex is originated from flow separation near the root region. This structure delays flow separation at the mid-span, leading to higher lift coefficient. Supported by NRF-2014M3C1B1033848.

  19. Identification of phlebovirus and arenavirus RNA sequences that stall and repress the exoribonuclease XRN1. (United States)

    Charley, Phillida A; Wilusz, Carol J; Wilusz, Jeffrey


    Regulated mRNA decay plays a vital role in determining both the level and quality of cellular gene expression. Viral RNAs must successfully evade this host RNA decay machinery to establish a productive infection. One way for RNA viruses to accomplish this is to target the cellular exoribonuclease XRN1, because this enzyme is accessible in the cytoplasm and plays a major role in mRNA decay. Members of the Flaviviridae use RNA structures in their 5'- or 3'-untranslated regions to stall and repress XRN1, effectively stabilizing viral RNAs while also causing significant dysregulation of host cell mRNA stability. Here, we use a series of biochemical assays to demonstrate that the 3'-terminal portion of the nucleocapsid (N) mRNA of Rift Valley fever virus, a phlebovirus of the Bunyaviridae family, also can effectively stall and repress XRN1. The region responsible for impeding XRN1 includes a G-rich portion that likely forms a G-quadruplex structure. The 3'-terminal portions of ambisense-derived transcripts of multiple arenaviruses also stalled XRN1. Therefore, we conclude that RNAs from two additional families of mammalian RNA viruses stall and repress XRN1. This observation. emphasizes the importance and commonality of this viral strategy to interfere with the 5'-to-3'-exoribonuclease component of the cytoplasmic RNA decay machinery. © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

  20. Theory/test correlation of helicopter rotor blade element airloads in the blade stall regime (United States)

    Bobo, C. J.


    The effects of stall on a rotor blade element in a three-dimensional rotating environment was investigated. The model rotor test provided blade element airloads and local boundary layer flow characteristics at the three-quarter blade radius position for a wide range of rotor operating conditions. A description of the test program and the test results are presented.

  1. Field rotor measurements. Data sets prepared for analysis of stall hysteresis

    Energy Technology Data Exchange (ETDEWEB)

    Aagaard Madsen, H.; Thirstrup Petersen, J. [Risoe National Lab. (Denmark); Bruining, A. [Delft Univ. of Technology (Netherlands); Brand, A. [ECN (Netherlands); Graham, M. [Imperical College (United Kingdom)


    As part of the JOULE-3 project `STALLVIB` an analysis and synthesis of the data from the field rotor experiments at ECN, Delft University, Imperial College, NREL and Risoe has been carried out. This has been done in order to see to what extent the data could be used for further development and validation of engineering dynamic stall models. A detailed investigation of the influence of the post-processing of the different data sets has been performed. Further, important statistical functions such as PSD spectra, coherence and transfer functions have been derived for the data sets which can be used as basis for evaluation of the quality of the data seen relative to actual application of the data. The importance of using an appropriate low-pass filtering to remove high frequency noise has been demonstrated when the relation between instantaneous values of e.g. {alpha} and C{sub N} is considered. In general, the complicated measurement on a rotor of {alpha} and w and the interpretation of these parameters combined with the strongly three-dimensional, turbulent flow field around the rotating blade has the consequence that it seems difficult to derive systematic information from the different data sets about stall hysteresis. In particular, the measurement of {alpha}, which determination of the stagnation point gives reasonable data below stall but fails in stall. On the other hand, measurements of {alpha} with a five hole pitot tube can be used also in the stall region. Another main problem is the non-dimensionalization of the coefficients C{sub N} and C{sub r}. If the dynamic pressure used for the non-dimensionalization is not fully correlated with the aerodynamic pressure over the considered airfoil section due to e.g. influence of the gravity on the pressure pipes, the hysteresis loops will be distorted. However, using the data with caution and applying a suitable post-processing as described by the different participants, it will probably be possible to obtain some

  2. Modeling dynamic stall on wind turbine blades under rotationally augmented flow fields

    Energy Technology Data Exchange (ETDEWEB)

    Guntur, S. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Schreck, S. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Sorensen, N. N. [Technical Univ. of Denmark, Lyngby (Denmark); Bergami, L. [Technical Univ. of Denmark, Lyngby (Denmark)


    It is well known that airfoils under unsteady flow conditions with a periodically varying angle of attack exhibit aerodynamic characteristics different from those under steady flow conditions, a phenomenon commonly known as dynamic stall. It is also well known that the steady aerodynamic characteristics of airfoils in the inboard region of a rotating blade differ from those under steady two-dimensional (2D) flow conditions, a phenomenon commonly known as rotational augmentation. This paper presents an investigation of these two phenomena together in the inboard parts of wind turbine blades. This analysis is carried out using data from three sources: (1) the National Renewable Energy Laboratory’s Unsteady Aerodynamics Experiment Phase VI experimental data, including constant as well as continuously pitching blade conditions during axial operation, (2) data from unsteady Delayed Detached Eddy Simulations (DDES) carried out using the Technical University of Denmark’s in-house flow solver Ellipsys3D, and (3) data from a simplified model based on the blade element momentum method with a dynamic stall subroutine that uses rotationally augmented steady-state polars obtained from steady Phase VI experimental sequences, instead of the traditional 2D nonrotating data. The aim of this work is twofold. First, the blade loads estimated by the DDES simulations are compared to three select cases of the N sequence experimental data, which serves as a validation of the DDES method. Results show reasonable agreement between the two data in two out of three cases studied. Second, the dynamic time series of the lift and the moment polars obtained from the experiments are compared to those from the dynamic stall subroutine that uses the rotationally augmented steady polars. This allowed the differences between the stall phenomenon on the inboard parts of harmonically pitching blades on a rotating wind turbine and the classic dynamic stall representation in 2D flow to be

  3. Parametric analyses on dynamic stall control of rotor airfoil via synthetic jet

    Directory of Open Access Journals (Sweden)

    Qijun ZHAO


    Full Text Available The effects of synthetic jet control on unsteady dynamic stall over rotor airfoil are investigated numerically. A moving-embedded grid method and an Unsteady Reynolds Averaged Navier-Stokes (URANS solver coupled with k-ω Shear Stress Transport (SST turbulence model are established for predicting the complex flowfields of oscillatory airfoil under jet control. Additionally, a velocity boundary condition modeled by sinusoidal function has been developed to fulfill the perturbation effect of periodic jet. The validity of present CFD method is evaluated by comparisons of the calculated results of baseline dynamic stall case for rotor airfoil and jet control case for VR-7B airfoil with experimental data. Then, parametric analyses are conducted emphatically for an OA212 rotor airfoil to investigate the effects of jet control parameters (jet location, dimensionless frequency, momentum coefficient, jet angle, jet type and dual-jet on dynamic stall characteristics of rotor airfoil. It is demonstrated by the calculated results that efficiency of jet control could be improved with specific momentum coefficient and jet angle when the jet is located near separation point of rotor airfoil. Furthermore, the dual-jet could improve control efficiency more obviously on dynamic stall of rotor airfoil with respect to the unique jet, and the influence laws of dual-jet’s angles and momentum coefficients on control effects are similar to those of the unique jet. Finally, unsteady aerodynamic characteristics of rotor via synthetic jet which is located on the upper surface of rotor blade in forward flight are calculated, and as a result, the aerodynamic characteristics of rotor are improved compared with the baseline. The results indicate that synthetic jet has the capability in improving aerodynamic characteristics of rotor. Keywords: Airfoil, Dynamic stall characteristics, Flow control, Moving-embedded grid methodology, Navier-Stokes equations, Parametric

  4. Power reduction and the radial limit of stall delay in revolving wings of different aspect ratio. (United States)

    Kruyt, Jan W; van Heijst, GertJan F; Altshuler, Douglas L; Lentink, David


    Airplanes and helicopters use high aspect ratio wings to reduce the power required to fly, but must operate at low angle of attack to prevent flow separation and stall. Animals capable of slow sustained flight, such as hummingbirds, have low aspect ratio wings and flap their wings at high angle of attack without stalling. Instead, they generate an attached vortex along the leading edge of the wing that elevates lift. Previous studies have demonstrated that this vortex and high lift can be reproduced by revolving the animal wing at the same angle of attack. How do flapping and revolving animal wings delay stall and reduce power? It has been hypothesized that stall delay derives from having a short radial distance between the shoulder joint and wing tip, measured in chord lengths. This non-dimensional measure of wing length represents the relative magnitude of inertial forces versus rotational accelerations operating in the boundary layer of revolving and flapping wings. Here we show for a suite of aspect ratios, which represent both animal and aircraft wings, that the attachment of the leading edge vortex on a revolving wing is determined by wing aspect ratio, defined with respect to the centre of revolution. At high angle of attack, the vortex remains attached when the local radius is shorter than four chord lengths and separates outboard on higher aspect ratio wings. This radial stall limit explains why revolving high aspect ratio wings (of helicopters) require less power compared with low aspect ratio wings (of hummingbirds) at low angle of attack and vice versa at high angle of attack. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  5. The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon. (United States)

    von der Malsburg, Karina; Shao, Sichen; Hegde, Ramanujan S


    Cytosolic ribosomes that stall during translation are split into subunits, and nascent polypeptides trapped in the 60S subunit are ubiquitinated by the ribosome quality control (RQC) pathway. Whether the RQC pathway can also target stalls during cotranslational translocation into the ER is not known. Here we report that listerin and NEMF, core RQC components, are bound to translocon-engaged 60S subunits on native ER membranes. RQC recruitment to the ER in cultured cells is stimulated by translation stalling. Biochemical analyses demonstrated that translocon-targeted nascent polypeptides that subsequently stall are polyubiquitinated in 60S complexes. Ubiquitination at the translocon requires cytosolic exposure of the polypeptide at the ribosome-Sec61 junction. This exposure can result from either failed insertion into the Sec61 channel or partial backsliding of translocating nascent chains. Only Sec61-engaged nascent chains early in their biogenesis were relatively refractory to ubiquitination. Modeling based on recent 60S-RQC and 80S-Sec61 structures suggests that the E3 ligase listerin accesses nascent polypeptides via a gap in the ribosome-translocon junction near the Sec61 lateral gate. Thus the RQC pathway can target stalled translocation intermediates for degradation from the Sec61 channel. © 2015 von der Malsburg et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (

  6. Fractional charges

    International Nuclear Information System (INIS)

    Saminadayar, L.


    20 years ago fractional charges were imagined to explain values of conductivity in some materials. Recent experiments have proved the existence of charges whose value is the third of the electron charge. This article presents the experimental facts that have led theorists to predict the existence of fractional charges from the motion of quasi-particles in a linear chain of poly-acetylene to the quantum Hall effect. According to the latest theories, fractional charges are neither bosons nor fermions but anyons, they are submitted to an exclusive principle that is less stringent than that for fermions. (A.C.)

  7. Internal Flow of a High Specific-Speed Diagonal-Flow Fan (Rotor Outlet Flow Fields with Rotating Stall

    Directory of Open Access Journals (Sweden)

    Norimasa Shiomi


    Full Text Available We carried out investigations for the purpose of clarifying the rotor outlet flow fields with rotating stall cell in a diagonal-flow fan. The test fan was a high–specific-speed (ns=1620 type of diagonal-flow fan that had 6 rotor blades and 11 stator blades. It has been shown that the number of the stall cell is 1, and its propagating speed is approximately 80% of its rotor speed, although little has been known about the behavior of the stall cell because a flow field with a rotating stall cell is essentially unsteady. In order to capture the behavior of the stall cell at the rotor outlet flow fields, hot-wire surveys were performed using a single-slant hotwire probe. The data obtained by these surveys were processed by means of a double phase-locked averaging technique, which enabled us to capture the flow field with the rotating stall cell in the reference coordinate system fixed to the rotor. As a result, time-dependent ensemble averages of the three-dimensional velocity components at the rotor outlet flow fields were obtained. The behavior of the stall cell was shown for each velocity component, and the flow patterns on the meridional planes were illustrated.

  8. Integrated Qs Al Mudatsir in the reality group counseling to grow the character of students academic responsibility

    Directory of Open Access Journals (Sweden)

    Asroful Kadafi


    The emotional development of students in early teens showed a sensitive and recreative nature (critical, emotions are often negative and temperamental. This negative passion is evidenced by the findings in the field of Indonesian teenagers, such as Tawuran, promiscuity, students who dare to do nasty with school friends (Tirto, 2013. Many factors are the cause, one of which is still the weak character of academic responsibility that students have. This problem becomes a serious problem in the world of education Indonesia. Therefore, it is natural for educational practitioners to take solutive steps to overcome the problem. One education practitioner who has a strategic position to handle the case is Counselor. Counselors are deemed able to provide practical solutions through Reality Group Counseling services by integrating spiritual values (Islam to foster student academic responsibilities. Reality group counseling emphasizes the growth of personal responsibility. This advice is also in line with Islamic values that encourage individuals always to be responsible for every action as reflected in the QS. Al Muddassir: 38.

  9. Investigation of the wind climate in connection with double-stall on wind turbines in Tarifa[Spain]; Undersoegelse af vindklima i forbindelse med dobbelt-stall paa vindmoeller i Tarifa

    Energy Technology Data Exchange (ETDEWEB)

    Christensen, T. [ELSAMPROJEKT A/S, Fredericia, (Denmark); Jensen, L.E. [LM Glasfiber A/S, Lunderskov (Denmark)


    This project has compiled data to allow the Danish manufacturers of wind turbines and blades to improve their knowledge of double stall. On the basis of the double stall difficulties different types of turbines using different makes of blades have encountered in the Tarifa area in Southern Spain, meteorological parameters and production data from two turbines have been measured for a local site. Part of the acquired data have been analysed to reach an understanding of why double stall occurs. The analysis strongly suggests that a change in power level due to double stall can be a result of several external factors: (1) Rain cleaning the blades. (2) A more or less random change in the wind speed components uv, or w, which in some cases can affect a - probably - fairly thick boundary layer. (3) A change in the high frequency turbulence where the vortex impact is too insignificant to affect an - almost - randomly - thick boundary layer. (au)

  10. Why Do Promising Therapies Stall in Development and How Can We Move Them Forward? (United States)

    Wegner, Craig D; Goodwin, Andrew; Cook, Jon C; Allamneni, Krishna; Sohn, Jane; McVean, Maralee

    There are many reasons that molecules fail to progress to market and various principles of risk-benefit decisions that can help drive the molecule through development. This symposium included discussions on global strategies involved in pushing promising molecules to market, what to do when a molecule stalls in its progress to market, and options for rescuing the molecule and pushing it forward again. Innovative partnerships that bring stalled drugs back into clinical development were also addressed. A regulatory perspective on common reasons for a molecule to fail in its forward progress was presented. In addition, situations arise when a third-party advisory committee can provide input to help overcome issues identified by a regulatory agency. Using examples from the private and public domain, presentations centered on how to repurpose a molecule and when more science is needed.

  11. A Beddoes-Leishman type dynamic stall model in state-space and indicial formulations

    DEFF Research Database (Denmark)

    Hansen, M.H.; Gaunaa, Mac; Aagaard Madsen, Helge


    This report contains a description of a Beddoes-Leishman type dynamic stall model in both a state-space and an indicial function formulation. The model predicts the unsteady aerodynamic forces and moment on an airfoil section undergoing arbitrary motionin heave, lead-lag, and pitch. The model...... features, such as overshoot of the lift, in the stall region. The linearized model is shown to give identicalresults to the full model for small amplitude oscillations. Furthermore, it is shown that the response of finite thichkness airfoils can be reproduced to a high accuracy by the use of specific...... is carried out by comparing the response of the model with inviscid solutions and observing the general behavior of the model using known airfoil data as input. Theproposed dynamic model gives results identical to inviscid solutions within the attached-flow region; and it exhibits the expected dynamic...

  12. Grid support of a wind farm with active stall wind turbines and AC grid connection

    DEFF Research Database (Denmark)

    Hansen, Anca Daniela; Sørensen, Poul Ejnar; Iov, F.


    grid connection. The designed control system has the task of enabling such a wind farm to provide the best grid support. It is based on two control levels: a supervisory control level, which controls the power production of the whole farm by sending out reference signals to each individual wind turbine......, and a local control level, which ensures that the reference power signals at the wind turbine level are reached. The ability of active stall wind farms with AC grid connection to control the power production to the reference power ordered by the operators is assessed and discussed by means of simulations.......One of the main concerns in the grid integration of large wind farms is their ability to behave as active controllable components in the power system. This article presents the design of a new integrated power control system for a wind farm made up exclusively of active stall wind turbines with AC...

  13. Charge preamplifier

    International Nuclear Information System (INIS)

    Chaminade, R.; Passerieux, J.P.


    We describe a charge preamplifier having the following properties: - large open loop gain giving both stable gain and large input charge transfer; - stable input grid current with aging and without any adjustment; - fairly fast rise; - nearly optimum noise performance; - industrial material. (authors)

  14. Simulation model of a transient fault controller for an active-stall wind turbine

    Energy Technology Data Exchange (ETDEWEB)

    Jauch, C.; Soerensen, P.; Bak Jensen, B.


    This paper describes the simulation model of a controller that enables an active-stall wind turbine to ride through transient faults. The simulated wind turbine is connected to a simple model of a power system. Certain fault scenarios are specified and the turbine shall be able to sustain operation in case of such faults. The design of the controller is described and its performance assessed by simulations. The control strategies are explained and the behaviour of the turbine discussed. (author)

  15. Charging machine

    International Nuclear Information System (INIS)

    Medlin, J.B.


    A charging machine for loading fuel slugs into the process tubes of a nuclear reactor includes a tubular housing connected to the process tube, a charging trough connected to the other end of the tubular housing, a device for loading the charging trough with a group of fuel slugs, means for equalizing the coolant pressure in the charging trough with the pressure in the process tubes, means for pushing the group of fuel slugs into the process tube and a latch and a seal engaging the last object in the group of fuel slugs to prevent the fuel slugs from being ejected from the process tube when the pusher is removed and to prevent pressure liquid from entering the charging machine. 3 claims, 11 drawing figures

  16. Origins location of the outflow tract ventricular arrhythmias exhibiting qrS pattern or QS pattern with a notch on the descending limb in lead V1. (United States)

    Lin, Cong; Zheng, Cheng; Zhou, De-Pu; Li, Xiao-Wei; Wu, Shu-Jie; Lin, Jia-Feng


    Ventricular outflow tract(VOT) ventricular arrhythmias(VAs) presenting qrS pattern or QS pattern with a notch on the descending limb in lead V1 were consistently thought of arising from the commissure between left and right coronary cusp (L-RCC) by previous studies. However, we found they could originate from other anatomic structures in VOT. This study aimed to investigate the exact origin of this kind VAs. Forty-nine patients of VOT premature ventricular contrations/ventricular tachycardia(PVCs/VT) with lead V1 presenting qrS pattern or QS pattern with a notch on the descending limb undergoing successful radiofrequency catheter ablation(RFCA) in our center were analyzed. 12-lead electrocardiogram(ECG) of these PVCs/VT were summarized. Among these PVCs/VT, 37 cases exhibited qrS morphology in lead V1, 12 cases presented QS pattern with a notch on the descending limb in the same lead. Based on the successful ablation sites, these PVCs/VT were divided into 2 groups: (1)Right ventricular outflow tract(RVOT) group (26 cases), and (2) Left ventricular outflow tract (LVOT) group(23 cases, 4 cases originating from the left coronary cusp(LCC), 2 from the right coronary cusp(RCC), 16 from the L-RCC, 1 from the area inferior to LCC(ILCC)). The ECG characteristics of each PVCs/VT were analyzed. Among these PVCs/VT, applying the precordial transitional zone index(TZ index) pattern or QS pattern with a notch on descending limb not only arising from L-RCC, but also RVOT, LCC, RCC and ILCC. Combining TZ index and QRS morphology in lead I to predict origin site of these kind VAs is a convenient, simple and reliable method and facilitates the RFCA procedure.

  17. An automatic system for the detection of dairy cows lying behaviour in free-stall barns

    Directory of Open Access Journals (Sweden)

    Simona M.C. Porto


    Full Text Available In this paper, a method for the automatic detection of dairy cow lying behaviour in free-stall barns is proposed. A computer visionbased system (CVBS composed of a video-recording system and a cow lying behaviour detector based on the Viola Jones algorithm was developed. The CVBS performance was tested in a head-to-head free stall barn. Two classifiers were implemented in the software component of the CVBS to obtain the cow lying behaviour detector. The CVBS was validated by comparing its detection results with those generated from visual recognition. This comparison allowed the following accuracy indices to be calculated: the branching factor (BF, the miss factor (MF, the sensitivity, and the quality percentage (QP. The MF value of approximately 0.09 showed that the CVBS missed one cow every 11 well detected cows. Conversely, the BF value of approximately 0.08 indicated that one false positive was detected every 13 well detected cows. The high value of approximately 0.92 obtained for the sensitivity index and that obtained for QP of about 0.85 revealed the ability of the proposed system to detect cows lying in the stalls.

  18. Piloted Simulator Evaluation Results of Flight Physics Based Stall Recovery Guidance (United States)

    Lombaerts, Thomas; Schuet, Stefan; Stepanyan, Vahram; Kaneshige, John; Hardy, Gordon; Shish, Kimberlee; Robinson, Peter


    In recent studies, it has been observed that loss of control in flight is the most frequent primary cause of accidents. A significant share of accidents in this category can be remedied by upset prevention if possible, and by upset recovery if necessary, in this order of priorities. One of the most important upsets to be recovered from is stall. Recent accidents have shown that a correct stall recovery maneuver remains a big challenge in civil aviation, partly due to a lack of pilot training. A possible strategy to support the flight crew in this demanding context is calculating a recovery guidance signal, and showing this signal in an intuitive way on one of the cockpit displays, for example by means of the flight director. Different methods for calculating the recovery signal, one based on fast model predictive control and another using an energy based approach, have been evaluated in four relevant operational scenarios by experienced commercial as well as test pilots in the Vertical Motion Simulator at NASA Ames Research Center. Evaluation results show that this approach could be able to assist the pilots in executing a correct stall recovery maneuver.

  19. The Relationships between Selection and Processing Food with Escherichia coli Contaminant on Food Stall Serving

    Directory of Open Access Journals (Sweden)

    Tris Eryando


    Full Text Available Escherichia coli in food stalls surrounding the X Campuss in Depok, year 2012. The research conducted to examine food safety, which were served in surrounding the campus X in Depok. Escherichia coli (E. coli existence was used to indicate the quality of hygiene and sanitation of the food that was served. Using the cross sectional method, the research examined the persons who served the food to be sold in the food stalls in the campus. There were 173 food servers chosen as the respondents from 10 different food stalls around the university. The existence of E. coli examined in the microbiology laboratory in the Faculty of Public Health. Using the most probable number (MPN method found that 59.54% of the food served in the campus were contaminated E. coli. Factors affecting the existence of E. coli were the raw materials (vegetables treated and the length of cooking of the materials (rice/beens. The improper treatment such as washing with no running water or even unwashed vegetables had 5 times risk of the E. coli contamination. Cooking less than 15 minutes was also more risky than cooking more than 15 minutes. As a result, this is very important to find a method to improve knowledge and to increase practical skills in food safety. Furthermore, in this research area may give contribution to avoid E. coli contamination which will prevent unnecessary illness among students in the campus.

  20. Replisome stall events have shaped the distribution of replication origins in the genomes of yeasts (United States)

    Newman, Timothy J.; Mamun, Mohammed A.; Nieduszynski, Conrad A.; Blow, J. Julian


    During S phase, the entire genome must be precisely duplicated, with no sections of DNA left unreplicated. Here, we develop a simple mathematical model to describe the probability of replication failing due to the irreversible stalling of replication forks. We show that the probability of complete genome replication is maximized if replication origins are evenly spaced, the largest inter-origin distances are minimized, and the end-most origins are positioned close to chromosome ends. We show that origin positions in the yeast Saccharomyces cerevisiae genome conform to all three predictions thereby maximizing the probability of complete replication if replication forks stall. Origin positions in four other yeasts—Kluyveromyces lactis, Lachancea kluyveri, Lachancea waltii and Schizosaccharomyces pombe—also conform to these predictions. Equating failure rates at chromosome ends with those in chromosome interiors gives a mean per nucleotide fork stall rate of ∼5 × 10−8, which is consistent with experimental estimates. Using this value in our theoretical predictions gives replication failure rates that are consistent with data from replication origin knockout experiments. Our theory also predicts that significantly larger genomes, such as those of mammals, will experience a much greater probability of replication failure genome-wide, and therefore will likely require additional compensatory mechanisms. PMID:23963700

  1. Near Stall Flow Analysis in the Transonic Fan of the RTA Propulsion System (United States)

    Hah, Chunill


    Turbine-based propulsion systems for access to space have been investigated at NASA Glenn Research center. A ground demonstrator engine for validation testing has been developed as a part of the program. The demonstrator, the Revolutionary Turbine Accelerator (RTA-1), is a variable cycle turbofan ramjet designed to transition from an augmented turbofan to a ramjet that produces the thrust required to accelerate the vehicle to Mach 4. The RTA-1 is designed to accommodate a large variation in bypass ratio from sea level static to Mach 4 flight condition. A key component of this engine is a new fan stage that accommodates these large variations in bypass ratio and flow ranges. In the present study, unsteady flow behavior in the fan of the RTA-1 is studied in detail with large eddy simulation (LES) and the numerical results are compared with measured data. During the experimental study of the fan stage, humming sound was detected at 100 % speed near stall operation. The main purpose of the study is to investigate details of the unsteady flow behavior at near stall operation and to identify a possible cause of the hum. The large eddy simulation of the current flow field reproduces main features of the measured flow very well. The LES simulation indicates that non-synchronous flow instability develops as the fan operates toward the stall limit. The FFT analysis of the calculated wall pressure shows that the rotating flow instability has the characteristic frequency that is about 50% of the blade passing frequency.

  2. Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells. (United States)

    Giraud, Matthieu; Yoshida, Hideyuki; Abramson, Jakub; Rahl, Peter B; Young, Richard A; Mathis, Diane; Benoist, Christophe


    Aire is a transcriptional regulator that induces expression of peripheral tissue antigens (PTA) in thymic medullary epithelial cells (MECs), driving immunological self-tolerance in differentiating T cells. To elucidate its mechanistic pathways, we examined its transcriptional impact in MECs in vivo by microarray analysis with mRNA-spanning probes. This analysis revealed initiation of Aire-activated genes to be comparable in Aire-deficient and wild-type MECs, but with a block to elongation after 50-100 bp in the absence of Aire, suggesting activation by release of stalled polymerases by Aire. In contrast, patterns of activation by transcription factors such as Klf4 were consistent with regulation of initiation. Mapping of Aire and RNA polymerase-II (Pol-II) by ChIP and high-throughput sequencing (ChIP-seq) revealed that Aire bound all Pol-II-rich transcriptional start sites (TSS), irrespective of its eventual effect. However, the genes it preferentially activated were characterized by a relative surfeit of stalled polymerases at the TSS, which resolved once Aire was introduced into cells. Thus, transcript mapping and ChIP-seq data indicate that Aire activates ectopic transcription not through specific recognition of PTA gene promoters but by releasing stalled polymerases.

  3. Short revolving wings enable hovering animals to avoid stall and reduce drag (United States)

    Lentink, David; Kruyt, Jan W.; Heijst, Gertjan F.; Altshuler, Douglas L.


    Long and slender wings reduce the drag of airplanes, helicopters, and gliding animals, which operate at low angle of attack (incidence). Remarkably, there is no evidence for such influence of wing aspect ratio on the energetics of hovering animals that operate their wings at much higher incidence. High incidence causes aircraft wings to stall, hovering animals avoid stall by generating an attached vortex along the leading edge of their wings that elevates lift. Hypotheses that explain this capability include the necessity for a short radial distance between the shoulder joint and wing tip, measured in chord lengths, instead of the long tip-to-tip distance that elevates aircraft performance. This stems from how hovering animals revolve their wings around a joint, a condition for which the precise effect of aspect ratio on stall performance is unknown. Here we show that the attachment of the leading edge vortex is determined by wing aspect ratio with respect to the center of rotation-for a suite of aspect ratios that represent both animal and aircraft wings. The vortex remains attached when the local radius is shorter than 4 chord lengths, and separates outboard on more slender wings. Like most other hovering animals, hummingbirds have wing aspect ratios between 3 and 4, much stubbier than helicopters. Our results show this makes their wings robust against flow separation, which reduces drag below values obtained with more slender wings. This revises our understanding of how aspect ratio improves performance at low Reynolds numbers.

  4. CHARGE syndrome

    Directory of Open Access Journals (Sweden)

    Prasad Chitra


    Full Text Available Abstract CHARGE syndrome was initially defined as a non-random association of anomalies (Coloboma, Heart defect, Atresia choanae, Retarded growth and development, Genital hypoplasia, Ear anomalies/deafness. In 1998, an expert group defined the major (the classical 4C's: Choanal atresia, Coloboma, Characteristic ears and Cranial nerve anomalies and minor criteria of CHARGE syndrome. Individuals with all four major characteristics or three major and three minor characteristics are highly likely to have CHARGE syndrome. However, there have been individuals genetically identified with CHARGE syndrome without the classical choanal atresia and coloboma. The reported incidence of CHARGE syndrome ranges from 0.1–1.2/10,000 and depends on professional recognition. Coloboma mainly affects the retina. Major and minor congenital heart defects (the commonest cyanotic heart defect is tetralogy of Fallot occur in 75–80% of patients. Choanal atresia may be membranous or bony; bilateral or unilateral. Mental retardation is variable with intelligence quotients (IQ ranging from normal to profound retardation. Under-development of the external genitalia is a common finding in males but it is less apparent in females. Ear abnormalities include a classical finding of unusually shaped ears and hearing loss (conductive and/or nerve deafness that ranges from mild to severe deafness. Multiple cranial nerve dysfunctions are common. A behavioral phenotype for CHARGE syndrome is emerging. Mutations in the CHD7 gene (member of the chromodomain helicase DNA protein family are detected in over 75% of patients with CHARGE syndrome. Children with CHARGE syndrome require intensive medical management as well as numerous surgical interventions. They also need multidisciplinary follow up. Some of the hidden issues of CHARGE syndrome are often forgotten, one being the feeding adaptation of these children, which needs an early aggressive approach from a feeding team. As the child

  5. Dynamics and Control of Three-Dimensional Perching Maneuver under Dynamic Stall Influence (United States)

    Feroskhan, Mir Alikhan Bin Mohammad

    Perching is a type of aggressive maneuver performed by the class 'Aves' species to attain precision point landing with a generally short landing distance. Perching capability is desirable on unmanned aerial vehicles (UAVs) due to its efficient deceleration process that potentially expands the functionality and flight envelope of the aircraft. This dissertation extends the previous works on perching, which is mostly limited to two-dimensional (2D) cases, to its state-of-the-art threedimensional (3D) variety. This dissertation presents the aerodynamic modeling and optimization framework adopted to generate unprecedented variants of the 3D perching maneuver that include the sideslip perching trajectory, which ameliorates the existing 2D perching concept by eliminating the undesirable undershoot and reliance on gravity. The sideslip perching technique methodically utilizes the lateral and longitudinal drag mechanisms through consecutive phases of yawing and pitching-up motion. Since perching maneuver involves high rates of change in the angles of attack and large turn rates, introduction of three internal variables thus becomes necessary for addressing the influence of dynamic stall delay on the UAV's transient post-stall behavior. These variables are then integrated into a static nonlinear aerodynamic model, developed using empirical and analytical methods, and into an optimization framework that generates a trajectory of sideslip perching maneuver, acquiring over 70% velocity reduction. An impact study of the dynamic stall influence on the optimal perching trajectories suggests that consideration of dynamic stall delay is essential due to the significant discrepancies in the corresponding control inputs required. A comparative study between 2D and 3D perching is also conducted to examine the different drag mechanisms employed by 2D and 3D perching respectively. 3D perching is presented as a more efficient deceleration technique with respect to spatial costs and

  6. The effect of alphacypermethrin-treated mesh protection against African horse sickness virus vectors on jet stall microclimate, clinical variables and faecal glucocorticoid metabolites of horses. (United States)

    Page, Patrick; Ganswindt, Andre; Schoeman, Johan; Venter, Gert; Guthrie, Alan


    African horse sickness (AHS) is of importance to health and international trade in horses worldwide. During export from and transit through AHS endemic countries or zones, physical and chemical measures to protect horses from the vectors of AHS virus (AHSV) are recommended by the World Organization for Animal Health. Protection of containerized air transport systems for horses (jet stalls) with alphacypermethrin insecticide-treated high density polyethylene mesh is effective in reducing the Culicoides midge vector attack rate. In order to determine the effect of this mesh on jet stall ventilation and horse welfare under temperate climatic conditions, jet stall microclimate, clinical variables and faecal glucocorticoid metabolite (FGM) levels of 12 horses were monitored during overnight housing in either a treated or untreated stall in two blocks of a 2 × 3 randomized crossover design. Temperature difference between the treated stall and outside was significantly higher than the difference between the untreated stall and outside at 1/15 time points only (P = 0.045, r = 0.70). Relative humidity (RH) difference between the treated stall and outside did not differ from the untreated stall and outside. Temperature and RH in the treated stall were highly and significantly correlated with outside temperature (r = 0.96, P < 0.001) and RH (r = 0.95, P < 0.001), respectively. No significant differences were detected between rectal temperatures, pulse and respiratory rates of horses in the treated stall compared to the untreated stall. Mean FGM concentrations for horses housed in the treated stall peaked earlier (24 h) and at a higher concentration than horses housed in the untreated stall (48 h), but were not significantly different from baseline. No significant difference was detected in FGM concentrations when the treated and untreated stall groups were compared at individual time points up to 72 h after exiting the jet stall. Alphacypermethrin

  7. The acceptability, efficacy and safety of quinacrine non-surgical sterilization (QS), tubectomy and vasectomy in 5 provinces in the Red River Delta, Vietnam: a follow-up of 15,190 cases. (United States)

    Hieu, D T; Luong, T T; Anh, P T; Ngoc, D H; Duong, L Q


    To compare the safety, efficacy and acceptability of quinacrine sterilization (QS), tubectomy and vasectomy in Vietnam. This study was initiated in January 1998 and completed in February 2000. A sample of 9 districts in 5 provinces, where the prevalence of QS was known to be high, was selected. Every person sterilized in these 9 districts between January 1, 1988 and March 31, 1998 was identified and systematically interviewed by family planning clinicians who had received special training for this project. A total of 15,982 sterilization users were identified and 15,190 were interviewed and examined, including a gynecologic exam, if needed: a follow-up rate of 95%. Of those interviewed, 9,753 used tubectomy, 3,734 used QS and 1,703 used vasectomy. All three methods were found to be safe, although morbidity associated with tubectomy was more serious than with QS or vasectomy. No deaths were reported. After more than 5 years of follow-up, tubectomy had the lowest failure rate: 1.0%, followed by 4.1% with vasectomy. A pregnancy rate of 13.2% was reported with quinacrine, although only a small fraction of these failures were confirmed. A strong preference for QS was found. QS has an important role to play in sterilization services in Vietnam.

  8. Animal hygiene assessment of microclimate in semi open free-stall barns for dairy cows

    Directory of Open Access Journals (Sweden)

    D. Dimov


    Full Text Available Abstract. The study was conducted in three semi open free-stall barns (B1, B2, and B3 for dairy cows with capacities for 120, 120 and 500 cows, respectively, from three different dairy farms (F-1, F-2 and F-3, situated in Central Southern Bulgaria. The investigated farms had the same production system – loose housing in semi open free-stall dairy barn. For each of the farms the main microclimatic parameters – air temperature, relative humidity and speed of airflow were recorded twice a month at 10.00 h 12.00 h, 14.00 h, 16.00 h and 18.00 h of the day inside the barns in three main technological zones - above the stalls, above manure and feed alleys and outside the buildings. It was found that: a Microclimatic parameters (air temperature, air relative humidity and speed of airflow in technological zones (above the stalls, the manure and feed alleys of three semi open free-stall dairy barns meet the animal hygienic requirements for all seasons according to Regulation No. 44 (2006. Exceptions are some values of relative humidity in B1 and B2 in the spring, and in B1 in winter and summer, which are lower than the minimum humidity (50% according to the standard. b The investigated barns are characterized with poor insulation and do not provide enough isolation from the external ambient temperatures. With the exception of winter, the temperature of the air inside the buildings was lower than that outside, with minor differences for all seasons. The fans in the barns have no effect on the inside air temperature, especially in summer. There was a risk of higher temperatures mainly during the summer period. c There is no significant difference between the average temperatures, air humidity and speed of airflow in all technological zones of the investigated barns. d The largest and statistically significant is the difference between the relative air humidity outside and inside the building in Farm 3, followed by buildings in Farm 1 and 2, where the

  9. Prediction of RNA Polymerase II recruitment, elongation and stalling from histone modification data (United States)


    Background Initiation and elongation of RNA polymerase II (RNAPII) transcription is regulated by both DNA sequence and chromatin signals. Recent breakthroughs make it possible to measure the chromatin state and activity of core promoters genome-wide, but dedicated computational strategies are needed to progress from descriptive annotation of data to quantitative, predictive models. Results Here, we describe a computational framework which with high accuracy can predict the locations of core promoters, the amount of recruited RNAPII at the promoter, the amount of elongating RNAPII in the gene body, the mRNA production originating from the promoter and finally also the stalling characteristics of RNAPII by considering both quantitative and spatial features of histone modifications around the transcription start site (TSS). As the model framework can also pinpoint the signals that are the most influential for prediction, it can be used to infer underlying regulatory biology. For example, we show that the H3K4 di- and tri- methylation signals are strongly predictive for promoter location while the acetylation marks H3K9 and H3K27 are highly important in estimating the promoter usage. All of these four marks are found to be necessary for recruitment of RNAPII but not sufficient for the elongation. We also show that the spatial distributions of histone marks are almost as predictive as the signal strength and that a set of histone marks immediately downstream of the TSS is highly predictive of RNAPII stalling. Conclusions In this study we introduce a general framework to accurately predict the level of RNAPII recruitment, elongation, stalling and mRNA expression from chromatin signals. The versatility of the method also makes it ideally suited to investigate other genomic data. PMID:22047616

  10. Prediction of RNA Polymerase II recruitment, elongation and stalling from histone modification data

    Directory of Open Access Journals (Sweden)

    Chen Yun


    Full Text Available Abstract Background Initiation and elongation of RNA polymerase II (RNAPII transcription is regulated by both DNA sequence and chromatin signals. Recent breakthroughs make it possible to measure the chromatin state and activity of core promoters genome-wide, but dedicated computational strategies are needed to progress from descriptive annotation of data to quantitative, predictive models. Results Here, we describe a computational framework which with high accuracy can predict the locations of core promoters, the amount of recruited RNAPII at the promoter, the amount of elongating RNAPII in the gene body, the mRNA production originating from the promoter and finally also the stalling characteristics of RNAPII by considering both quantitative and spatial features of histone modifications around the transcription start site (TSS. As the model framework can also pinpoint the signals that are the most influential for prediction, it can be used to infer underlying regulatory biology. For example, we show that the H3K4 di- and tri- methylation signals are strongly predictive for promoter location while the acetylation marks H3K9 and H3K27 are highly important in estimating the promoter usage. All of these four marks are found to be necessary for recruitment of RNAPII but not sufficient for the elongation. We also show that the spatial distributions of histone marks are almost as predictive as the signal strength and that a set of histone marks immediately downstream of the TSS is highly predictive of RNAPII stalling. Conclusions In this study we introduce a general framework to accurately predict the level of RNAPII recruitment, elongation, stalling and mRNA expression from chromatin signals. The versatility of the method also makes it ideally suited to investigate other genomic data.

  11. Replication Stalling and Heteroduplex Formation within CAG/CTG Trinucleotide Repeats by Mismatch Repair

    KAUST Repository

    Viterbo, David


    Trinucleotide repeat expansions are responsible for at least two dozen neurological disorders. Mechanisms leading to these large expansions of repeated DNA are still poorly understood. It was proposed that transient stalling of the replication fork by the repeat tract might trigger slippage of the newly-synthesized strand over its template, leading to expansions or contractions of the triplet repeat. However, such mechanism was never formally proven. Here we show that replication fork pausing and CAG/CTG trinucleotide repeat instability are not linked, stable and unstable repeats exhibiting the same propensity to stall replication forks when integrated in a yeast natural chromosome. We found that replication fork stalling was dependent on the integrity of the mismatch-repair system, especially the Msh2p-Msh6p complex, suggesting that direct interaction of MMR proteins with secondary structures formed by trinucleotide repeats in vivo, triggers replication fork pauses. We also show by chromatin immunoprecipitation that Msh2p is enriched at trinucleotide repeat tracts, in both stable and unstable orientations, this enrichment being dependent on MSH3 and MSH6. Finally, we show that overexpressing MSH2 favors the formation of heteroduplex regions, leading to an increase in contractions and expansions of CAG/CTG repeat tracts during replication, these heteroduplexes being dependent on both MSH3 and MSH6. These heteroduplex regions were not detected when a mutant msh2-E768A gene in which the ATPase domain was mutated was overexpressed. Our results unravel two new roles for mismatch-repair proteins: stabilization of heteroduplex regions and transient blocking of replication forks passing through such repeats. Both roles may involve direct interactions between MMR proteins and secondary structures formed by trinucleotide repeat tracts, although indirect interactions may not be formally excluded.

  12. Stall, Spiculate, or Run Away: The Fate of Fibers Growing towards Fluctuating Membranes (United States)

    Daniels, D. R.; Marenduzzo, D.; Turner, M. S.


    We study the dynamics of a growing semiflexible fiber approaching a membrane at an angle. At late times we find three regimes: fiber stalling, when growth stops, runaway, in which the fiber bends away from the membrane, and another regime in which spicules form. We discuss which regions of the resulting “phase diagram” are explored by (i) single and bundled actin fibers in living cells, (ii) sickle hemoglobin fibers, and (iii) microtubules inside vesicles. We complement our analysis with 3D stochastic simulations.

  13. Prediction of H.A.W.T. blade stall and performance

    Energy Technology Data Exchange (ETDEWEB)

    Giannakidis, G.; Graham, J.M.R. [Imperial College, Dept. of Aeronautics, London (United Kingdom)


    A model is being developed for the prediction of Horizontal Axis Wind Turbine blade stall and performance coupled with a simple aeroelastic analysis model. For the aerodynamic calculation a two dimensional unsteady Navier-Stokes solver on a sectional basis on the blade is coupled with a three dimensional vortex lattice wake. Pressure coefficient distributions are calculated from the two dimensional viscous flow in each blade section. The aerodynamic computations are coupled with a vibrating beam model in order to incorporate flapwise deformations of the blade. (au) 17 refs.

  14. Modeling dynamic stall on wind turbine blades under rotationally augmented flow fields

    DEFF Research Database (Denmark)

    Guntur, Srinivas; Sørensen, Niels N.; Schreck, Scott


    Experiment Phase VI experimental data, including constant as well as continuously pitching blade conditions during axial operation; (2) data from unsteady delayed detached eddy simulations (DDES) carried out using the Technical University of Denmark’s in-house flow solver Ellipsys3D; and (3) data from...... agreement between the model and the experimental data in many cases, which suggests that the current two-dimensional dynamic stall model as used in blade element momentum-based aeroelastic codes may provide a reasonably accurate representation of three-dimensional rotor aerodynamics when used in combination...

  15. Modelling of multiple short-length-scale stall cells in an axial compressor using evolved GMDH neural networks

    International Nuclear Information System (INIS)

    Amanifard, N.; Nariman-Zadeh, N.; Farahani, M.H.; Khalkhali, A.


    Over the past 15 years there have been several research efforts to capture the stall inception nature in axial flow compressors. However previous analytical models could not explain the formation of short-length-scale stall cells. This paper provides a new model based on evolved GMDH neural network for transient evolution of multiple short-length-scale stall cells in an axial compressor. Genetic Algorithms (GAs) are also employed for optimal design of connectivity configuration of such GMDH-type neural networks. In this way, low-pass filter (LPF) pressure trace near the rotor leading edge is modelled with respect to the variation of pressure coefficient, flow rate coefficient, and number of rotor rotations which are defined as inputs


    Directory of Open Access Journals (Sweden)



    Full Text Available Although individual and social behavior of cattle has been studied extensively under pasture and loose housing conditions, similar behavioral data for partial or total confinement housing are limited. Essentially, the 24- h time budget represents the net response of a cow to her environment (Grant, 2003. Daily time budget was first introduced by Grant and Albright (in 2000 for cows housed in free-stall environment. Choices in stabling and management affect the behavior, health, longevity and performance of cows. Behavior while resting, eating, ruminating, urinating or defecating provides additional information about comfort. In the current study were used ten Romanian Black and White multiparous cows, housed in a tie stall barn 24 hours per day. Experiments were carried out during the cold season, in February 2008. Cows monitored were in their first hundred days of lactation. In our study cows spent resting on average 379.9 minutes (6.33 hours, value that represents 26.38 % from the days interval. Time devoted to feeding was on average 341.9 minutes (5.69 hours, in 17.5 periods. Rumination had place on average in 17.3 periods and a total time of 517.5 minutes (8.62 hours. Cows adopted lying position on average 581.2 minutes (40.36% from 24-h and standing position on average in 858.7 minutes (59.63% from 24-h.

  17. 14-3-3 Proteins regulate exonuclease 1-dependent processing of stalled replication forks.

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    Kim Engels


    Full Text Available Replication fork integrity, which is essential for the maintenance of genome stability, is monitored by checkpoint-mediated phosphorylation events. 14-3-3 proteins are able to bind phosphorylated proteins and were shown to play an undefined role under DNA replication stress. Exonuclease 1 (Exo1 processes stalled replication forks in checkpoint-defective yeast cells. We now identify 14-3-3 proteins as in vivo interaction partners of Exo1, both in yeast and mammalian cells. Yeast 14-3-3-deficient cells fail to induce Mec1-dependent Exo1 hyperphosphorylation and accumulate Exo1-dependent ssDNA gaps at stalled forks, as revealed by electron microscopy. This leads to persistent checkpoint activation and exacerbated recovery defects. Moreover, using DNA bi-dimensional electrophoresis, we show that 14-3-3 proteins promote fork progression under limiting nucleotide concentrations. We propose that 14-3-3 proteins assist in controlling the phosphorylation status of Exo1 and additional unknown targets, promoting fork progression, stability, and restart in response to DNA replication stress.

  18. Numerical study on a single bladed vertical axis wind turbine under dynamic stall

    Energy Technology Data Exchange (ETDEWEB)

    Bangga, Galih [Institute of Aerodynamics and Gas Dynamics, University of Stuttgart, Stuttgart (Germany); Hutomo, Go; Sasongko, Herman [Dept. of Mechanical Engineering, Institut Teknologi Sepuluh Nopember, Surabaya (Indonesia); Wiranegara, Raditya [School of Mechanical Aerospace and Civil Engineering, University of Manchester, Manchester (United Kingdom)


    The aim of this study is to investigate the flow development of a single bladed vertical axis wind turbine using Computational fluid dynamics (CFD) methods. The blade is constructed using the NACA 0012 profile and is operating under stalled conditions at tip speed ratio of 2. Two dimensional simulations are performed using a commercial CFD package, ANSYS Fluent 15.0, employing the Menter-SST turbulence model. For the preliminary study, simulations of the NACA 0012 airfoil under static conditions are carried out and compared with available measurement data and calculations using the boundary layer code XFOIL. The CFD results under the dynamic case are presented and the resulting aerodynamic forces are evaluated. The turbine is observed to generate negative power at certain azimuth angles which can be divided into three main zones. The blade vortex interaction is observed to strongly influence the flow behavior near the blade and contributes to the power production loss. However, the impact is considered small since it covers only 6.4 % of the azimuth angle range where the power is negative compared to the dynamic stall impact which covers almost 22 % of the azimuth angle range.

  19. Wind-up of a spanwise vortex in deepening transition and stall

    Energy Technology Data Exchange (ETDEWEB)

    Smith, F.T.; Bowles, R.I. [University Coll., London (United Kingdom). Dept. of Mathematics; Walker, J.D.A. [Mechanical Engineering Department, Packard Laboratory No. 19, Lehigh University, Bethlehem, PA 18015 (United States)


    A fundamental flow problem of unsteady wind-up of a spanwise vortex is studied in this theoretical work on deepening dynamic stall and transition in a boundary layer, internal layer or related unsteady motion. It examines the nonlinear evolution of the spanwise vortex produced when the local wall pressure develops a maximum or minimum, subsequent to the finite-time break-up of an interacting layer and the impact of normal pressure gradients. The evolution is controlled by an inner-outer interaction between the effects of the normal pressure gradient and the momentum jumps across and outside the vortex, which is situated near the strong inflexion point induced in the mean flow. Although the work concentrates on a particular internal-flow context, many of the flow properties found are generic and in particular apply for a more general case including external flows. Analysis and associated computations point to two main distinct trends in the vortex response, depending to a large extent on a parameter gauging the relative strengths of the above effects. The response is either an explosive one, provoking enhanced wind-up, growth and pressure in the vortex, or it is implosive, causing the vortex to shrink and virtually empty itself through unwinding, leaving little local pressure variation. A further discussion includes the after-effects of this vortex response and some of the connections with experiments and direct computations on deepening stall and transition. (orig.)

  20. Experimental Methods Applied in a Study of Stall Flutter in an Axial Flow Fan

    Directory of Open Access Journals (Sweden)

    John D. Gill


    Full Text Available Flutter testing is an integral part of aircraft gas turbine engine development. In typical flutter testing blade mounted sensors in the form of strain gages and casing mounted sensors in the form of light probes (NSMS are used. Casing mounted sensors have the advantage of being non-intrusive and can detect the vibratory response of each rotating blade. Other types of casing mounted sensors can also be used to detect flutter of rotating blades. In this investigation casing mounted high frequency response pressure transducers are used to characterize the part-speed stall flutter response of a single stage unshrouded axial-flow fan. These dynamic pressure transducers are evenly spaced around the circumference at a constant axial location upstream of the fan blade leading edge plane. The pre-recorded experimental data at 70% corrected speed is analyzed for the case where the fan is back-pressured into the stall flutter zone. The experimental data is analyzed using two probe and multi-probe techniques. The analysis techniques for each method are presented. Results from these two analysis methods indicate that flutter occurred at a frequency of 411 Hz with a dominant nodal diameter of 2. The multi-probe analysis technique is a valuable method that can be used to investigate the initiation of flutter in turbomachines.

  1. Active flow control of the laminar separation bubble on a plunging airfoil near stall (United States)

    Pande, Arth; Agate, Mark; Little, Jesse; Fasel, Hermann


    The effects of small amplitude (A/c = 0.048) high frequency (πfc/U∞ = 0.70) plunging motion on the X-56A airfoil are examined experimentally at Re = 200,000 for 12° angle of attack (CL,MAX = 12.25°) . The purpose of this research is to study the aerodynamic influence of structural motion when the wing is vibrating close to its eigenfrequency near static stall. Specific focus is placed on the laminar separation bubble (LSB) near the leading edge and its control via plasma actuation. In the baseline case, the leading edge bubble bursts during the oscillation cycle causing moment stall. A collaborative computational effort has shown that small amplitude forcing at a frequency that is most amplified by the primary instability of the LSB (FLSB+= 1, Fc+= 52) generates coherent spanwise vortices that entrain freestream momentum, thus reducing separation all while maintaining a laminar flow state. Results (PIV and surface pressure) indicate that a similar control mechanism is effective in the experiments. This is significant given the existence of freestream turbulence in the wind tunnel which has been shown to limit the efficacy of this active flow control technique in a model problem using Direct Numerical Simulation. The implications of these results are discussed.

  2. Compliance with NAGCAT work practices recommendations for youth cleaning service alleys in stall barns. (United States)

    Canan, B D; Asti, L; Heaney, C; Ashida, S; Renick, K; Xiang, H; Stallones, L; Jepsen, S D; Crawford, J M; Wilkins, J R


    Unintentional injury is the leading cause of death in the U.S. among persons 1 to 44 years of age. Over one million children and adolescents in the U.S. live, work, and/or play on farms, where injury risk is relatively high compared to other settings. In an attempt to reduce the number of childhood agricultural injuries occurring on farms, the North American Guidelines for Children's Agricultural Tasks (NAGCAT) was developed to assist parents or other caregivers in assigning developmentally appropriate chores to youth exposed to agricultural hazards. The results presented here are from a longitudinal study in which we obtained (self-reported) daily chore, injury, and safety behavior data from children and adolescents. We focused on one NAGCAT chore, cleaning a service alley in a stall barn, in order to estimate the extent of compliance with specific work practice recommendations contained in the NAGCAT. Our results indicated that among the four NAGCAT-recommended safety practices for cleaning service alleys in stall barns (wearing nonskid shoes, leather gloves, a respirator, and eye protection), wearing non-skid shoes was the only safety practice reported with any degree of regularity. Overall, boys were more likely to wear non-skid shoes compared to girls. In addition, older youth were generally more likely to report higher work practice compliance compared to younger youth.

  3. Ethnic Dimensions of Guatemala's Stalled Transition: A Parity-Specific Analysis of Ladino and Indigenous Fertility Regimes. (United States)

    Grace, Kathryn; Sweeney, Stuart


    In some contemporary populations, fertility levels appear to plateau, with women maintaining a consistently high level of fertility for a relatively extended period. Because this plateau does not reflect the historical patterns observed in Europe, the focus of most studies on fertility patterns, mechanisms underlying the plateau and the reinstatement of a decline have not been fully explored and are not fully understood. Through the construction of fertility histories of 25,000 women using multiple years of health survey data, we analyze some of the components of stalled fertility as they pertain to Guatemala, the only Central American country to have experienced a stalled fertility decline.

  4. Development and Psychometric Validation of the EDE-QS, a 12 Item Short Form of the Eating Disorder Examination Questionnaire (EDE-Q.

    Directory of Open Access Journals (Sweden)

    Nicole Gideon

    Full Text Available The aim of this study was to develop and validate a short form of the Eating Disorder Examination Questionnaire (EDE-Q for routine, including session by session, outcome assessment.The current, 28-item version (6.0 of the EDE-Q was completed by 489 individuals aged 18-72 with various eating disorders recruited from three UK specialist eating disorder services. Rasch analysis was carried out on factors identified by means of principal component analysis, which in combination with expert ratings informed the development of an EDE-Q short form. The shortened questionnaire's reliability, validity and sensitivity was assessed based on online data collected from students of a UK university and volunteers with a history of eating disorders recruited from a national eating disorders charity aged 18-74 (N = 559.A 12-item short form, the Eating Disorder Examination Questionnaire Short (EDE-QS was derived. The new measure showed high internal consistency (Cronbach's α = .913 and temporal stability (ICC = .93; p < .001. It was highly correlated with the original EDE-Q (r = .91 for people without ED; r = .82 for people with ED and other measures of eating disorder and comorbid psychopathology. It was sufficiently sensitive to distinguish between people with and without eating disorders.The EDE-QS is a brief, reliable and valid measure of eating disorder symptom severity that performs similarly to the EDE-Q and that lends itself for the use of sessional outcome monitoring in treatment and research.

  5. Development and Psychometric Validation of the EDE-QS, a 12 Item Short Form of the Eating Disorder Examination Questionnaire (EDE-Q) (United States)

    Gideon, Nicole; Hawkes, Nick; Mond, Jonathan; Saunders, Rob; Tchanturia, Kate; Serpell, Lucy


    Objective The aim of this study was to develop and validate a short form of the Eating Disorder Examination Questionnaire (EDE-Q) for routine, including session by session, outcome assessment. Method The current, 28-item version (6.0) of the EDE-Q was completed by 489 individuals aged 18–72 with various eating disorders recruited from three UK specialist eating disorder services. Rasch analysis was carried out on factors identified by means of principal component analysis, which in combination with expert ratings informed the development of an EDE-Q short form. The shortened questionnaire’s reliability, validity and sensitivity was assessed based on online data collected from students of a UK university and volunteers with a history of eating disorders recruited from a national eating disorders charity aged 18–74 (N = 559). Results A 12-item short form, the Eating Disorder Examination Questionnaire Short (EDE-QS) was derived. The new measure showed high internal consistency (Cronbach’s α = .913) and temporal stability (ICC = .93; p eating disorder and comorbid psychopathology. It was sufficiently sensitive to distinguish between people with and without eating disorders. Discussion The EDE-QS is a brief, reliable and valid measure of eating disorder symptom severity that performs similarly to the EDE-Q and that lends itself for the use of sessional outcome monitoring in treatment and research. PMID:27138364

  6. [Minimal provider volume in total knee replacement : an analysis of the external quality assurance program of North Rhine-Westphalia (QS-NRW)]. (United States)

    Kostuj, T; Schulze-Raestrup, U; Noack, M; Buckup, K; Smektala, R


    A minimal provider volume for total knee replacement (TKR) was introduced in 2006. Does this lead to an improvenment in quality or not? The records of treatment in the compulsory external quality assurance program of the Land of North Rhine-Westphalia (QS-NRW) were evaluated. A total of 125,324 comparable records from the QS-NRW program were available to determine the appearance of general and surgical complications. In a logistical regression model the risk factors age, gender, ASA classification, comorbidity and duration were taken into account. A significant reduction could only be shown for pneumonia, thrombotic events and lung embolisms as well as vascular injury. In 2006 and 2007 malpositioning of implants was significantly higher and from 2005 to 2008 the number of fractures rose compared to 2004. Deep infections and reoperations did not change significantly during the whole study period. This evaluation could not show an improvement in quality due to the minimal provider volume. Thus the minimal provider volume should not be taken into account as a main criterion to improve quality. Further outcome studies and creating an arthroplasty register in Germany are more useful.

  7. Spins, Stalls, and Shutdowns: Pitfalls of Qualitative Policing and Security Research

    Directory of Open Access Journals (Sweden)

    Randy K. Lippert


    Full Text Available This article explores key elements of qualitative research on policing and security agencies, including barriers encountered and strategies to prevent them. While it is oft-assumed that policing/security agencies are difficult to access due to their clandestine or bureaucratic nature, this article demonstrates this is not necessarily the case, as access was gained for three distinct qualitative research projects. Yet, access and subsequent research were not without pitfalls, which we term security spins, security stalls, and security shutdowns. We illustrate how each was encountered and argue these pitfalls are akin to researchers falling into risk categories, not unlike those used by policing/security agents in their work. Before concluding we discuss methodological strategies for scholars to avoid these pitfalls and to advance research that critically interrogates the immense policing/security realm. URN:

  8. URANS simulations of separated flow with stall cells over an NREL S826 airfoil (United States)

    Sarlak, H.; Nishino, T.; Sørensen, J. N.


    A series of wind tunnel measurements and oil flow visualization was recently carried out at the Technical University of Denmark in order to investigate flow characteristics over a 14% thick NREL S826 airfoil at low Reynolds numbers. This paper aims at presenting numerical simulations of the same airfoil using unsteady Reynolds-averaged Navier-Stokes (URANS) approach. Results of the simulations are demonstrated in terms of mean flow velocity, lift and drag, as well as pressure distribution, and validated against available experimental data. The simulations are carried out with a wide computational domain (with a span-to-chord ratio of 5) and it is illustrated that the URANS approach is capable of predicting 3D spanwise structures, known as stall cells.

  9. Fixed-speed active-stall wind turbines in offshore applications

    DEFF Research Database (Denmark)

    Akhmatov, Vladislav; Nielsen, Arne Hejde


    A large offshore wind farm in the East Danish power system was commissioned in 2003 at Rodsand. The power capacity of the wind farm is 165 MW divided between 72 wind turbines. For this large offshore application, robust and well-known wind technology has been chosen in the form of fixed-speed, ac......, active-stall wind turbines equipped with induction generators. In this paper, maintaining and improving the short-term voltage stability is discussed and systematized in terms of this wind technology. Copyright (C) 2004 John Wiley Sons, Ltd.......A large offshore wind farm in the East Danish power system was commissioned in 2003 at Rodsand. The power capacity of the wind farm is 165 MW divided between 72 wind turbines. For this large offshore application, robust and well-known wind technology has been chosen in the form of fixed-speed...

  10. Performance augmentation with vortex generators: Design and testing for stall-regulated AWT-26 turbine

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, D.A. [Advanced Wind Turbines Inc., Seattle, WA (United States)


    A study investigated the use of vortex generators (VGs) for performance augmentation of the stall-regulated AWT-26 wind turbine. Based on wind-tunnel results and analysis, a VG array was designed for and tested on the AWT-26 prototype, designated Pt. Performance and loads data were measured for P1, both with and without VGs installed. The turbine performance with VGs met most of the design requirements; power output was increased at moderate wind speeds with a minimal effect on peak power. However, VG drag penalties caused a loss in power output for low wind speeds, such that performance with VGs resulted in a net decrease in AEP for wind speed sites up to 8.5 m/s. 8 refs., 8 figs., 3 tabs.

  11. Listeria phospholipases subvert host autophagic defenses by stalling pre-autophagosomal structures (United States)

    Tattoli, Ivan; Sorbara, Matthew T; Yang, Chloe; Tooze, Sharon A; Philpott, Dana J; Girardin, Stephen E


    Listeria can escape host autophagy defense pathways through mechanisms that remain poorly understood. We show here that in epithelial cells, Listeriolysin (LLO)-dependent cytosolic escape of Listeria triggered a transient amino-acid starvation host response characterized by GCN2 phosphorylation, ATF3 induction and mTOR inhibition, the latter favouring a pro-autophagic cellular environment. Surprisingly, rapid recovery of mTOR signalling was neither sufficient nor necessary for Listeria avoidance of autophagic targeting. Instead, we observed that Listeria phospholipases PlcA and PlcB reduced autophagic flux and phosphatidylinositol 3-phosphate (PI3P) levels, causing pre-autophagosomal structure stalling and preventing efficient targeting of cytosolic bacteria. In co-infection experiments, wild-type Listeria protected PlcA/B-deficient bacteria from autophagy-mediated clearance. Thus, our results uncover a critical role for Listeria phospholipases C in the inhibition of autophagic flux, favouring bacterial escape from host autophagic defense. PMID:24162724

  12. Study of Near-Stall Flow Behavior in a Modern Transonic Fan with Composite Sweep (United States)

    Hah, Chunill; Shin, Hyoun-Woo


    Detailed flow behavior in a modern transonic fan with a composite sweep is investigated in this paper. Both unsteady Reynolds-averaged Navier-Stokes (URANS) and Large Eddy Simulation (LES) methods are applied to investigate the flow field over a wide operating range. The calculated flow fields are compared with the data from an array of high-frequency response pressure transducers embedded in the fan casing. The current study shows that a relatively fine computational grid is required to resolve the flow field adequately and to calculate the pressure rise across the fan correctly. The calculated flow field shows detailed flow structure near the fan rotor tip region. Due to the introduction of composite sweep toward the rotor tip, the flow structure at the rotor tip is much more stable compared to that of the conventional blade design. The passage shock stays very close to the leading edge at the rotor tip even at the throttle limit. On the other hand, the passage shock becomes stronger and detaches earlier from the blade passage at the radius where the blade sweep is in the opposite direction. The interaction between the tip clearance vortex and the passage shock becomes intense as the fan operates toward the stall limit, and tip clearance vortex breakdown occurs at near-stall operation. URANS calculates the time-averaged flow field fairly well. Details of measured RMS static pressure are not calculated with sufficient accuracy with URANS. On the other hand, LES calculates details of the measured unsteady flow features in the current transonic fan with composite sweep fairly well and reveals the flow mechanism behind the measured unsteady flow field.

  13. Benchmarking welfare indicators in 73 free-stall dairy farms in north-western Spain (United States)

    Trillo, Yolanda; Quintela, Luis Angel; Barrio, Mónica; Becerra, Juan José; Peña, Ana Isabel; Vigo, Marcos; Garcia Herradon, Pedro


    The aim of this study was to describe the status of body condition score (BCS), hock injuries prevalence, locomotion and body hygiene score as animal welfare measures in 73 free-stall dairy cattle farms in Lugo (Spain). A benchmarking process was established across farms: (1) the animal-based indicators were ordered from low to high values; (2) The farms were classified into three categories based on the number of indicators within less than the 25th percentile, 25th to 75th percentile and above the 75th percentile. The median prevalence of unsuitable BCS, hock injuries and clinical lameness was (median (range)) 51.7 per cent (13.3 to 89.5 per cent), 40.0 per cent (7.0per cent to 100 per cent) and 9.0 per cent (0per cent to 60.0 per cent) respectively. The dirtiness of the cow’s coat had a high prevalence (73.0 per cent (37.5per cent to 100 per cent)). Most farms did not display consistently good or poor animal-based indicators and each farm had its own set of strong and weak points. Moreover, facilities design and management practices were described to understand source of the observations made of the cows. The incidence of overstocking was 31.5 per cent for stalls and 26.0 per cent for headlocks. The front lunge space was reduced (farms and they could benefit from others by changing management practices related to facilities and herds. PMID:29018530

  14. Reducing Respiratory Health Risks to Horses and Workers: A Comparison of Two Stall Bedding Materials

    Directory of Open Access Journals (Sweden)

    Markku Saastamoinen


    Full Text Available Stable air quality and the choice of bedding material are an important health issue both in horses and people working or visiting horse stables. Risks of impaired respiratory health are those that can especially be avoided by improving air quality in the stable. The choice of bedding material is particularly important in cold climate conditions; where horses are kept most of the day and year indoors throughout their life. This study examined the effect of two bedding materials; wood shavings and peat; on stable air quality and health of horses. Ammonia and dust levels were also measured to assess conditions in the stable. Ammonia was not detected or was at very low levels (<0.25 ppm in the boxes in which peat was used as bedding; but its concentration was clearly higher (1.5–7.0 ppm in stalls with wood shavings as bedding. Personal measurements of workers revealed quite high ammonia exposure (5.9 ppm8h in the boxes in which wood shavings were used; but no exposure was Animals 2015, 5 966 observed in stalls bedded with peat. The respiratory symptoms in horses increased regardless of the bedding material at the beginning of the study. The health status of the horses in the peat bedding group returned to the initial level in the end of the trial but horses bedded with wood shavings continued to be symptomatic. The hooves of the horses with peat bedding had a better moisture content than those of the horses bedded with wood shavings. The results suggest that peat is a better bedding material for horses than wood shavings regarding the health of both horses and stable workers.

  15. Climate trends account for stalled wheat yields in Australia since 1990. (United States)

    Hochman, Zvi; Gobbett, David L; Horan, Heidi


    Global food security requires that grain yields continue to increase to 2050, yet yields have stalled in many developed countries. This disturbing trend has so far been only partially explained. Here, we show that wheat yields in Australia have stalled since 1990 and investigate the extent to which climate trends account for this observation. Based on simulation of 50 sites with quality weather data, that are representative of the agro-ecological zones and of soil types in the grain zone, we show that water-limited yield potential declined by 27% over a 26 year period from 1990 to 2015. We attribute this decline to reduced rainfall and to rising temperatures while the positive effect of elevated atmospheric CO 2 concentrations prevented a further 4% loss relative to 1990 yields. Closer investigation of three sites revealed the nature of the simulated response of water-limited yield to water availability, water stress and maximum temperatures. At all three sites, maximum temperature hastened time from sowing to flowering and to maturity and reduced grain number per m 2 and average weight per grain. This 27% climate-driven decline in water-limited yield is not fully expressed in actual national yields. This is due to an unprecedented rate of technology-driven gains closing the gap between actual and water-limited potential yields by 25 kg ha -1  yr -1 enabling relative yields to increase from 39% in 1990 to 55% in 2015. It remains to be seen whether technology can continue to maintain current yields, let alone increase them to those required by 2050. © 2017 John Wiley & Sons Ltd.

  16. Low-Order Modeling of Dynamic Stall on Airfoils in Incompressible Flow (United States)

    Narsipur, Shreyas

    Unsteady aerodynamics has been a topic of research since the late 1930's and has increased in popularity among researchers studying dynamic stall in helicopters, insect/bird flight, micro air vehicles, wind-turbine aerodynamics, and ow-energy harvesting devices. Several experimental and computational studies have helped researchers gain a good understanding of the unsteady ow phenomena, but have proved to be expensive and time-intensive for rapid design and analysis purposes. Since the early 1970's, the push to develop low-order models to solve unsteady ow problems has resulted in several semi-empirical models capable of effectively analyzing unsteady aerodynamics in a fraction of the time required by high-order methods. However, due to the various complexities associated with time-dependent flows, several empirical constants and curve fits derived from existing experimental and computational results are required by the semi-empirical models to be an effective analysis tool. The aim of the current work is to develop a low-order model capable of simulating incompressible dynamic-stall type ow problems with a focus on accurately modeling the unsteady ow physics with the aim of reducing empirical dependencies. The lumped-vortex-element (LVE) algorithm is used as the baseline unsteady inviscid model to which augmentations are applied to model unsteady viscous effects. The current research is divided into two phases. The first phase focused on augmentations aimed at modeling pure unsteady trailing-edge boundary-layer separation and stall without leading-edge vortex (LEV) formation. The second phase is targeted at including LEV shedding capabilities to the LVE algorithm and combining with the trailing-edge separation model from phase one to realize a holistic, optimized, and robust low-order dynamic stall model. In phase one, initial augmentations to theory were focused on modeling the effects of steady trailing-edge separation by implementing a non-linear decambering

  17. Effect of stall design on dairy calf transition to voluntary feeding on an automatic milk feeder after introduction to group housing. (United States)

    Wilson, Tanya R; LeBlanc, Stephen J; DeVries, Trevor J; Haley, Derek B


    Automatic milk feeders (AMF) for young dairy calves are widely used in the dairy industry. These feeders are thought to have benefits for calf health and welfare and may reduce labor required for feeding; however, little is known about how calves adapt to feeding with AMF. The objective of this study was to observe the effects of feeding stall design on calves learning to use the AMF. The hypothesis was that solid side stalls, compared with steel bar stalls, would result in a longer latency to approach and feed from the AMF without assistance. A total of 147 Holstein calves (80 male and 67 female) were enrolled at 4 d of age, introduced to a group pen, and, at the same time, trained on an AMF. For training, calves were allowed to suck on the trainer's fingers and guided to the teat. Calves were allocated to 1 of 2 stall designs at the pen level, depending on which treatment cohort they were born into, either with steel bar stall walls (n = 46 male, 34 female calves) or with solid side stall walls (n = 34 male, 33 female calves). For 72 h after introductory training on the AMF, data from the feeders were collected and calf behavior was monitored by video. Outcomes measured included latency to first voluntary visit to the feeder and to first feeding, time spent in the feeder, amount of milk consumed over 72 h, number of retraining sessions required (retrained if linear regression models or a Poisson model for the outcome of retraining. For certain outcomes the effects of stall design interacted with difficulty of training (willingness to enter feeder and drink); for the 38% of calves that were scored as moderately difficult to train on a scale of easy, moderate, or difficult, treatment (stall design) differences were detected. These calves took 2× longer to lick or bite toward the nipple, 2× longer to first voluntarily feeding, and consumed less milk over 72 h following training when trained on the steel bar stall design. These results suggest simple features of a

  18. Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer

    DEFF Research Database (Denmark)

    Sabbatini, Paul J; Ragupathi, Govind; Hood, Chandra


    PURPOSE: To characterize the safety and immunogenicity of a heptavalent antigen-keyhole limpet hemocyanin (KLH) plus QS21 vaccine construct in patients with epithelial ovarian, fallopian tube, or peritoneal cancer in second or greater complete clinical remission. EXPERIMENTAL DESIGN: Eleven...... administered at weeks 1, 2, 3, 7, and 15. Periodic blood and urine samples were obtained to monitor safety (complete blood count, comprehensive panel, amylase, thyroid-stimulating hormone, and urinalysis) and antibody production (ELISA, fluorescence-activated cell sorting, and complement-dependent cytotoxicity......). RESULTS: Eleven patients were included in the safety analysis; 9 of 11 patients remained on study for at least 2 weeks past fourth vaccination and were included in the immunologic analysis (two withdrew, disease progression). The vaccine was well tolerated. Self-limited and mild fatigue (maximum grade 2...

  19. CHARGE Association

    Directory of Open Access Journals (Sweden)

    Semanti Chakraborty


    Full Text Available We present here a case of 17-year-old boy from Kolkata presenting with obesity, bilateral gynecomastia, mental retardation, and hypogonadotrophic hypogonadism. The patient weighed 70 kg and was of 153 cm height. Facial asymmetry (unilateral facial palsy, gynecomastia, decreased pubic and axillary hair, small penis, decreased right testicular volume, non-palpable left testis, and right-sided congenital inguinal hernia was present. The patient also had disc coloboma, convergent squint, microcornea, microphthalmia, pseudohypertelorism, low set ears, short neck, and choanalatresia. He had h/o VSD repaired with patch. Laboratory examination revealed haemoglobin 9.9 mg/dl, urea 24 mg/dl, creatinine 0.68 mg/dl. IGF1 77.80 ng/ml (decreased for age, GH <0.05 ng/ml, testosterone 0.25 ng/ml, FSH-0.95 ΅IU/ml, LH 0.60 ΅IU/ml. ACTH, 8:00 A.M cortisol, FT3, FT4, TSH, estradiol, DHEA-S, lipid profile, and LFT was within normal limits. Prolactin was elevated at 38.50 ng/ml. The patient′s karyotype was 46XY. Echocardiography revealed ventricularseptal defect closed with patch, grade 1 aortic regurgitation, and ejection fraction 67%. Ultrasound testis showed small right testis within scrotal sac and undescended left testis within left inguinal canal. CT scan paranasal sinuses revealed choanalatresia and deviation of nasal septum to the right. Sonomammography revealed bilateral proliferation of fibroglandular elements predominantly in subareoalar region of breasts. MRI of brain and pituitary region revealed markedly atrophic pituitary gland parenchyma with preserved infundibulum and hypothalamus and widened suprasellar cistern. The CHARGE association is an increasingly recognized non-random pattern of congenital anomalies comprising of coloboma, heart defect, choanal atresia, retarded growth and development, genital hypoplasia, ear abnormalities, and/or deafness. [1] These anomalies have a higher probability of occurring together. In this report, we have

  20. Has Uganda experienced any stalled fertility transitions? Reflecting on the last four decades (1973-2011). (United States)

    Kabagenyi, Allen; Reid, Alice; Rutaremwa, Gideon; Atuyambe, Lynn M; Ntozi, James P M


    Persistent high fertility is associated with mother and child mortality. While most regions in the world have experienced declines in fertility rates, there are conflicting views as to whether Uganda has entered a period of fertility transition. There are limited data available that explicitly detail the fertility trends and patterns in Uganda over the last four decades, from 1973 to 2011. Total fertility rate (TFR) is number of live births that a woman would have throughout her reproductive years if she were subject to the prevailing age specific fertility patterns. The current TFR for Uganda stands at 6.2 children born per woman, which is one of the highest in the region. This study therefore sought to examine whether there has been a fertility stall in Uganda using all existing Demographic Health Survey data, to provide estimates for the current fertility levels and trends in Uganda, and finally to examine the demographic and socioeconomic factors responsible for fertility levels in Uganda. This is a secondary analysis of data from five consecutive Ugandan Demographic Health Surveys (UDHS); 1988/1989, 1995, 2000/2001, 2006 and 2011. Using pooled data to estimate for fertility levels, patterns and trends, we applied a recently developed fertility estimation approach. A Poisson regression model was also used to analyze fertility differentials over the study period. Over the studied period, fertility trends and levels fluctuated from highs of 8.8 to lows of 5.7, with no specific lag over the study period. These findings suggest Uganda is at the pre-transitional stage, with indications of imminent fertility rate reductions in forthcoming years. Marital status remained a strong predictor for number of children born, even after controlling for other variables. This study suggests there is no evidence of a fertility stall in Uganda, but demonstrates an onset of fertility transition in the country. If this trend continues, Uganda will experience a low fertility rate in

  1. Mutuelles de santé en Afrique : caractéristiques et relations contractuelles avec les prestataires de soins pour la prise en charge de la qualité des soins. (United States)

    Ndiaye, Pascal; Vanlerberghe, Veerle; Lefèvre, Pierre; Criel, Bart


    En Afrique, une part importante de la population est encore confrontée à plusieurs barrières pour accéder aux soins. Les mutuelles de santé (MS) sont mises en place pour réduire la barrière financière et assurer à leurs membres un accès à des soins de qualité. Les MS établissent des relations avec les prestataires de soins sous forme de contrat, dont certaines clauses peuvent contenir des notions de qualité des soins (QS). A travers une vue d'ensemble de la typologie de 180 MS de 14 pays (dans Afrique Ouest et Centrale), cet article vise à analyser dans quelle mesure les caractéristiques des MS influencent la mise en œuvre de mécanismes contractuels susceptibles de faciliter la discussion sur la QS. L'hypothèse de cette association a été étudiée avec trois types de caractéristiques (taille, utilisation des services et volume des soins achetés) et huit variables relatives à la contractualisation et la QS (existence d'un contrat, organisation de rencontres, fréquence de ces rencontres, présence de notions de QS dans le contrat, négociation du contrat, révision du contrat, révision des clauses spécifiques à la QS et organisation de rencontres pour discuter de QS). Les MS de type communautaire représentent 80% des mutuelles étudiées (60% d'entre elles sont localisées en zone rurale). Les MS professionnelles représentent 17% et se concentrent principalement au Mali et en Côte d'Ivoire. La quasi-totalité des MS disposent de contrats écrits et contenant des notions relatives à la QS. Bien que les MS de grande taille ayant des résultats financiers importants négocient plus les aspects liés à la qualité des soins lors de l'élaboration de la convention, les MS de taille et aux performances financières plus modestes mettent en œuvre des mécanismes plus réguliers de concertation avec les prestataires. Ces rencontres sont susceptibles de créer un espace de prise en charge de la QS. © The Author(s) 2015.

  2. Design of a 21 m blade with Risø-A1 airfoils for active stall controlled wind turbines

    DEFF Research Database (Denmark)

    Fuglsang, Peter; Sangill, O.; Hansen, P.


    This is the final report, from the project, "Design of a Rotor/Airfoil Family for Active Stall-regulated Wind Turbines by Use of Multi-point Optimization". It describes the full scale testing of a 21 m wind turbine blade specially designed for active stallregulation. Design objectives were...... increased ratio of produced energy to turbine loads and more stable power control characteristics. Both were taken directly into account during the design of the blade using numerical optimization. The blade used theRisø-A1 airfoil family, which was specially designed for operation on wind turbine blades...... be concluded that the new LM 21.0 ASR blade could replace the LM 21.0P leading to improved cost efficiency and that the Risø-A1 airfoils were well suited for active stall control. With the newestablished knowledge of the actual airfoil characteristics, a possible future blade design could be made also...

  3. Experimental investigation of flow-induced vibration of a pitch-plunge NACA 0015 airfoil under deep dynamic stall

    Czech Academy of Sciences Publication Activity Database

    Šidlof, Petr; Vlček, Václav; Štěpán, M.


    Roč. 67, November (2016), s. 48-59 ISSN 0889-9746 R&D Projects: GA ČR GA13-10527S Institutional support: RVO:61388998 Keywords : NACA 0015 airfoil * aeroelasticity * stall flutter * dynamic stall * limit cycle oscillation * schlieren Subject RIV: BI - Acoustics Impact factor: 2.021, year: 2016

  4. Advance Ratio Effects on the Dynamic-stall Vortex of a Rotating Blade in Steady Forward Flight (United States)


    of the wind tunnel and is illustrated in Fig. 1. In order to simplify the operations, a two-bladed rotor design was preferred. The setup had wind turbines, compressors, helicopter rotors , and even insect wing aerodynamics. Dynamic stall occurs on rotating blades of a helicopter in forward...between the flow structure on helicopter rotor blades, wind turbine blades, and insect wings. Due to these wide engineering implications there has

  5. Parametric analyses for synthetic jet control on separation and stall over rotor airfoil

    Directory of Open Access Journals (Sweden)

    Zhao Guoqing


    Full Text Available Numerical simulations are performed to investigate the effects of synthetic jet control on separation and stall over rotor airfoils. The preconditioned and unsteady Reynolds-averaged Navier–Stokes equations coupled with a k − ω shear stream transport turbulence model are employed to accomplish the flowfield simulation of rotor airfoils under jet control. Additionally, a velocity boundary condition modeled by a sinusoidal function is developed to fulfill the perturbation effect of periodic jets. The validity of the present CFD procedure is evaluated by the simulated results of an isolated synthetic jet and the jet control case for airfoil NACA0015. Then, parametric analyses are conducted specifically for an OA213 rotor airfoil to investigate the effects of jet parameters (forcing frequency, jet location and momentum coefficient, jet direction, and distribution of jet arrays on the control effect of the aerodynamic characteristics of a rotor airfoil. Preliminary results indicate that the efficiency of jet control can be improved with specific frequencies (the best lift-drag ratio at F+ = 2.0 and jet angles (40° or 75° when the jets are located near the separation point of the rotor airfoil. Furthermore, as a result of a suitable combination of jet arrays, the lift coefficient of the airfoil can be improved by nearly 100%, and the corresponding drag coefficient decreased by 26.5% in comparison with the single point control case.

  6. Analysis of the grid connection sequence of stall- and pitch-controlled wind turbines

    Energy Technology Data Exchange (ETDEWEB)

    Quinonez-Varela, G.; Cruden, A.; Anaya-Lara, O.; Tumilty, R.; McDonald, J.R. [Univ. of Strathclyde, Inst. for Energy and Environment (United Kingdom)


    The realistic modelling of wind turbines and wind farms is crucial in any form of power system analysis, and consequently, knowledge about their electrical characteristics and performance is also vital. One of the operating conditions producing major transient interaction between a wind turbine generator and the local grid is the grid connection sequence itself, which is particularly significant in fixed-speed turbines. This paper presents experimental measurements of the grid connection sequence of both types of fixed speed wind turbines, i.e. stall- and pitch-controlled via a soft-start device performed at two existing wind farms. Some of the results evidenced significant discrepancies between the actual soft-start operating intervals and those stated/suggested by open literature. The discussion of the paper focuses on highlighting the importance of accurate modelling of the grid connection sequence in order to avoid erroneous estimations of the interaction between the turbine and the grid during this operating state, or inappropriate design of the grid connection. (au)

  7. ETAA1 acts at stalled replication forks to maintain genome integrity (United States)

    Bass, Thomas E.; Luzwick, Jessica W.; Kavanaugh, Gina; Carroll, Clinton; Dungrawala, Huzefa; Glick, Gloria G.; Feldkamp, Michael D.; Putney, Reid; Chazin, Walter J.; Cortez, David


    The ATR checkpoint kinase coordinates cellular responses to DNA replication stress. Budding yeast contain three activators of Mec1 (the ATR orthologue); however, only TOPBP1 is known to activate ATR in vertebrates. We identified ETAA1 as a replication stress response protein in two proteomic screens. ETAA1-deficient cells accumulate double-strand breaks, sister chromatid exchanges, and other hallmarks of genome instability. They are also hyper-sensitive to replication stress and have increased frequencies of replication fork collapse. ETAA1 contains two RPA-interaction motifs that localize ETAA1 to stalled replication forks. It also interacts with several DNA damage response proteins including the BLM/TOP3α/RMI1/RMI2 and ATR/ATRIP complexes. It binds ATR/ATRIP directly using a motif with sequence similarity to the TOPBP1-ATR activation domain; and like TOPBP1, ETAA1 acts as a direct ATR activator. ETAA1 functions in parallel to the TOPBP1/RAD9/HUS1/RAD1 pathway to regulate ATR and maintain genome stability. Thus, vertebrate cells contain at least two ATR activating proteins. PMID:27723720

  8. Why commercialization of gene therapy stalled; examining the life cycles of gene therapy technologies. (United States)

    Ledley, F D; McNamee, L M; Uzdil, V; Morgan, I W


    This report examines the commercialization of gene therapy in the context of innovation theories that posit a relationship between the maturation of a technology through its life cycle and prospects for successful product development. We show that the field of gene therapy has matured steadily since the 1980s, with the congruent accumulation of >35 000 papers, >16 000 US patents, >1800 clinical trials and >$4.3 billion in capital investment in gene therapy companies. Gene therapy technologies comprise a series of dissimilar approaches for gene delivery, each of which has introduced a distinct product architecture. Using bibliometric methods, we quantify the maturation of each technology through a characteristic life cycle S-curve, from a Nascent stage, through a Growing stage of exponential advance, toward an Established stage and projected limit. Capital investment in gene therapy is shown to have occurred predominantly in Nascent stage technologies and to be negatively correlated with maturity. Gene therapy technologies are now achieving the level of maturity that innovation research and biotechnology experience suggest may be requisite for efficient product development. Asynchrony between the maturation of gene therapy technologies and capital investment in development-focused business models may have stalled the commercialization of gene therapy.

  9. Flow-around modes for a rhomboid wing with a stall vortex in the shock layer (United States)

    Zubin, M. A.; Maximov, F. A.; Ostapenko, N. A.


    The results of theoretical and experimental investigation of an asymmetrical hypersonic flow around a V-shaped wing with the opening angle larger than π on the modes with attached shockwaves on forward edges, when the stall flow is implemented on the leeward wing cantilever behind the kink point of the cross contour. In this case, a vortex of nonviscous nature is formed in which the velocities on the sphere exceeding the speed of sound and resulting in the occurrence of pressure shocks with an intensity sufficient for the separation of the turbulent boundary layer take place in the reverse flow according to the calculations within the framework of the ideal gas. It is experimentally established that a separation boundary layer can exist in the reverse flow, and its structure is subject to the laws inherent to the reverse flow in the separation region of the turbulent boundary layer arising in the supersonic conic flow under the action of a shockwave incident to the boundary layer.

  10. Histone H2B mono-ubiquitylation maintains genomic integrity at stalled replication forks (United States)

    Northam, Matthew R.; Trujillo, Kelly M.


    Histone modifications play an important role in regulating access to DNA for transcription, DNA repair and DNA replication. A central player in these events is the mono-ubiquitylation of histone H2B (H2Bub1), which has been shown to regulate nucleosome dynamics. Previously, it was shown that H2Bub1 was important for nucleosome assembly onto nascent DNA at active replication forks. In the absence of H2Bub1, incomplete chromatin structures resulted in several replication defects. Here, we report new evidence, which shows that loss of H2Bub1 contributes to genomic instability in yeast. Specifically, we demonstrate that H2Bub1-deficient yeast accumulate mutations at a high frequency under conditions of replicative stress. This phenotype is due to an aberrant DNA Damage Tolerance (DDT) response upon fork stalling. We show that H2Bub1 normally functions to promote error-free translesion synthesis (TLS) mediated by DNA polymerase eta (Polη). Without H2Bub1, DNA polymerase zeta (Polζ) is responsible for a highly mutagenic alternative mechanism. While H2Bub1 does not appear to regulate other DDT pathways, error-free DDT mechanisms are employed by H2Bub1-deficient cells as another means for survival. However, in these instances, the anti-recombinase, Srs2, is essential to prevent the accumulation of toxic HR intermediates that arise in an unconstrained chromatin environment. PMID:27458205

  11. Exploring farmers’ seasonal and full year adoption of stall feeding of livestock in Tigrai region, Ethiopia

    Directory of Open Access Journals (Sweden)

    Hadush Muuz


    Full Text Available Adoption of stall feeding (SF of livestock was assessed in northern Ethiopia based on a household survey conducted in 2015. The study covered 21 communities in Tigrai to account for differences in agroecology. The purpose of this study was to understand the driving factors of full or seasonal SF adoption and its intensity. A Heckman selection model was used to estimate adoption and extent of adoption based on a model of technology adoption within an agricultural household framework, and Poisson Model for explaining the number of SF adopting seasons. The descriptive results indicate that 36% of the farmers were actually practicing SF in a full year whereas 55.6% were seasonal adopters in the study area. Empirical results of this study showed that our result is in favor of the Boserupian hypothesis indicating that small grazing land and large exclosure are associated with a higher probability of use of SF and with a higher number of SF adopting seasons. In a similar vein, small average village farm size stimulated SF adoption and adopting seasons, Availability of labor and a number of breed cows significantly increased the probability of using SF by 0.01% and 66% respectively. While animal shock had a marginal effect of 14%, factors such as access to information and early exposure increased SF adoption by about 18% and 6%. Similarly, the positive marginal effect of real milk price is 15%. However, SF appears to be less attractive to those farmers with more herd size and less crop residue.

  12. Workplace Charging. Charging Up University Campuses

    Energy Technology Data Exchange (ETDEWEB)

    Giles, Carrie [ICF International, Fairfax, VA (United States); Ryder, Carrie [ICF International, Fairfax, VA (United States); Lommele, Stephen [National Renewable Energy Lab. (NREL), Golden, CO (United States)


    This case study features the experiences of university partners in the U.S. Department of Energy's (DOE) Workplace Charging Challenge with the installation and management of plug-in electric vehicle (PEV) charging stations.

  13. Transonic Wind Tunnel Modernization for Experimental Investigation of Dynamic Stall in a Wide Range of Mach Numbers by Plasma Actuators with Combined Energy/Momentum Action (United States)


    wind tunnel for the study of plasma based methods for the control of dynamic stall for helicopter rotor blades. The tunnel has a 3D positioning...SECURITY CLASSIFICATION OF: This equipment grant supported the design and construction of a subsonic variable speed wind tunnel for the study of...plasma based methods for the control of dynamic stall for helicopter rotor blades. The tunnel has a 3D positioning system and servomotor mounted below

  14. Evaluation of free-stall mattress bedding treatments to reduce mastitis bacterial growth

    Energy Technology Data Exchange (ETDEWEB)

    Kristula, M.A.; Dou, Z.; Toth, J.D.; Smith, B.I.; Harvey, N.; Sabo, M. [University of Penn, Kennett Square, PA (United States)


    Bacterial counts were compared in free-stall mattresses and teat ends exposed to 5 treatments in a factorial study design on 1 dairy farm. Mattresses in five 30-cow groups were subjected to 1 of 5 bedding treatments every other day: 0.5 kg of hydrated limestone, 120 mL of commercial acidic conditioner, 1 kg of coal fly ash, 1 kg of kiln-dried wood shavings, and control (no bedding). Counts of coliforms, Klebsiella spp., Escherichia coli, and Streptococcus spp. were lowest on mattresses bedded with lime. Mattresses bedded with the commercial acidic conditioner had the next lowest counts for coliforms, Klebsiella spp., and Streptococcus spp. Wood shavings and the no-bedding control had the highest counts for coliform and Klebsiella spp. Compared with wood shavings or control, fly ash reduced the counts of coliforms, whereas for the other 3 bacterial groups, the reduction was not always significant. Streptococcus spp. counts were greatest in the control group and did not differ among the shavings and fly ash groups. Teat swab results indicated that hydrated lime was the only bedding treatment that significantly decreased the counts of both coliforms and Klebsiella spp. There were no differences in Streptococcus spp. numbers on the teats between any of the bedding treatments. Bacterial populations grew steadily on mattresses and were generally higher at 36 to 48 h than at 12 to 24 h, whereas bacterial populations on teats grew rapidly by 12 h and then remained constant. Hydrated lime was the only treatment that significantly reduced bacterial counts on both mattresses and teat ends, but it caused some skin irritation.

  15. Evaluation of rice mutant lines for resistance to brown planthopper, nilaparvata lugens stall

    International Nuclear Information System (INIS)



    The most important and common insect in rice cultivation in South East Asia is brown planthopper, nilaparvata lugens stall. Seven rice mutant lines produced by the National Atomic Energy Agency, Indonesia, were tested at IRRI, the Philippines for resistance to brown planthopper. Those mutant lines were Atomita 1, 627/10-3/PsJ, Atomita 2 and 627/4-E/PsJ originated from Pelita 1/1 which was irradiated with 0.2 kGy of gamma rays and A227/2/PsJ, A227/3/PsJ and A227/5/PsJ, originated from early maturing mutant A23/PsJ/72K from irradiated Pelita 1/1 which was irradiated with 0.1 kGy of gamma rays. Evaluation of resistance was carried out by seedling bulk screening, honeydew excretion, survival and population build up tests by using brown planthopper biotype 1, 2 and 3. Results of these tests showed that the seven tested mutant lines were resistant to biotype 1 but susceptible to biotype 2. Reaction to biotype 3 showed that six mutant lines tested were moderately resistant and only one mutant of 627/4-E/PsJ was susceptible. Reactions of the mutant lines to biotype 1, 2 and 3 were different from the resistant varieties, Mudgo or ASD-7. This indicated that mutant lines might have gene(s) for resistance which differed from those of resistant varieties. The results showed that resistance to brown planthopper is possible to be introduced in Indonesian rice varieties by means of mutations. (author)

  16. Stalled repair of lesions when present within a clustered DNA damage site

    International Nuclear Information System (INIS)

    Lomax, M.E.; Cunniffe, S.; O'Neill, P.


    Ionising radiation produces clustered DNA damages (two or more lesions within one or two helical turns of the DNA) which could challenge the repair mechanism(s) of the cell. Using purified base excision repair (BER) enzymes and synthetic oligonucleotides a number of recent studies have established the excision of a lesion within clustered damage sites is compromised. Evidence will be presented that the efficiency of repair of lesions within a clustered DNA damage site is reduced, relative to that of the isolated lesions, since the lifetime of both lesions is extended by up to four fold. Simple clustered damage sites, comprised of single-strand breaks, abasic sites and base damages, one or five bases 3' or 5' to each other, were synthesised in oligonucleotides and repair carried out in mammalian cell nuclear extracts. The rate of repair of the single-strand break/abasic site within these clustered damage sites is reduced, mainly due to inhibition of the DNA ligase. The mechanism of repair of the single-strand break/abasic site shows some asymmetry. Repair appears to be by the short-patch BER pathway when the lesions are 5' to each other. In contrast, when the lesions are 3' to each other repair appears to proceed along the long-patch BER pathway. The lesions within the cluster are processed sequentially, the single-strand break/abasic site being repaired before excision of 8-oxoG, limiting the formation of double-strand breaks to <2%. Stalled processing of clustered DNA damage extends the lifetime of the lesions to an extent that could have biological consequences, e.g. if the lesions are still present during transcription and/or at replication mutations could arise

  17. Effect of paddock vs. stall housing on 24 hour gastric pH within the proximal and ventral equine stomach. (United States)

    Husted, L; Sanchez, L C; Olsen, S N; Baptiste, K E; Merritt, A M


    Stall housing has been suggested as a risk factor for ulcer development in the equine stomach; however, the exact pathogenesis for this has not been established. To investigate the effect of 3 environmental situations (grass paddock, stall alone or stall with adjacent companion) on pH in the proximal and the ventral stomach. Six horses with permanently implanted gastric cannulae were used in a randomised, cross-over, block design. Each horse rotated through each of three 24 h environmental situations. Horses remained on their normal diet (grass hay ad libitum and grain b.i.d.) throughout the study. Intragastric pH was measured continuously for 72 h just inside the lower oesophageal sphincter (proximal stomach) and via a pH probe in the gastric cannula (ventral stomach). Neither proximal nor ventral 24 h gastric pH changed significantly between the 3 environmental situations. Mean hourly proximal gastric pH decreased significantly in the interval from 01.00-09.00 h compared to the interval from 13.00-20.00 h, regardless of environmental situation. Median hourly proximal pH only differed in the interval from 06.00-07.00 h compared to the interval 14.00-19.00 h. Neither mean nor median hourly ventral gastric pH varied significantly with the time of day. The change in housing status used in the current study did not affect acid exposure within either region of the equine stomach. The pH in the ventral stomach was uniformly stable throughout the study, while the proximal pH demonstrated a 24 h circadian pattern.

  18. The Effects of Gilts Housed Either in Group with the Electronic Sow Feeding System or Conventional Stall. (United States)

    Jang, J C; Jung, S W; Jin, S S; Ohh, S J; Kim, J E; Kim, Y Y


    This experiment was conducted to assess the welfare and productivity of gestating gilts in groups with the electronic sow feeding (ESF) system compared to conventional stalls. A total of 83 gilts (Yorkshire×Landrace) were housed into individual stalls to be artificially inseminated. Gilts confirmed pregnant were introduced to their treatment, conventional stalls (ST) or groups with the ESF system. All gilts were taken to the farrowing crates one week prior to their expected farrowing date. In the gestation period, there were no significant differences between gilts allocated to ST and ESF on growth performance. However, backfat thickness gain (p = 0.08) and body condition score (BCS) at 110 days of gestation (p = 0.10) tended to be higher in ESF gilts than ST. Likewise, gilts housed in group showed significantly higher estimated body muscle contents at 110 days of gestation (p = 0.02) and body muscle change during gestation (p = 0.01). There was a trend for a shorter parturition time in ESF gilts (p = 0.07). In the lactation period, group housed gilts showed a tendency to increased BCS changes (p = 0.06). Reproductive performance did not differ with the exception of piglet mortality (ST = 0.2 no. of piglets vs ESF = 0.4 no. of piglets; p = 0.01). In blood profiles, ST gilts showed a higher cortisol level at 110 days of gestation (p = 0.01). Weaning to estrus interval was shorter in gilts housed in ESF than ST (p = 0.01). In locomotory behaviors, ESF gilts recorded a tendency to elevate locomotion score at 36, 70, and 110 days of gestation (p = 0.07, p = 0.06, and p = 0.06, respectively). Similarly, ESF gilts showed significantly higher incidence of scratches at 36, 70, and 110 days of gestation (p = 0.01). Moreover, farrowing rates were higher in stall treatment (97.6%) compare to group housing treatment (95.2%). In conclusion, while group housed gilts with ESF system positively affected welfare status in combination with less physiologically stressful

  19. Theory of single-molecule controlled rotation experiments, predictions, tests, and comparison with stalling experiments in F1-ATPase. (United States)

    Volkán-Kacsó, Sándor; Marcus, Rudolph A


    A recently proposed chemomechanical group transfer theory of rotary biomolecular motors is applied to treat single-molecule controlled rotation experiments. In these experiments, single-molecule fluorescence is used to measure the binding and release rate constants of nucleotides by monitoring the occupancy of binding sites. It is shown how missed events of nucleotide binding and release in these experiments can be corrected using theory, with F 1 -ATP synthase as an example. The missed events are significant when the reverse rate is very fast. Using the theory the actual rate constants in the controlled rotation experiments and the corrections are predicted from independent data, including other single-molecule rotation and ensemble biochemical experiments. The effective torsional elastic constant is found to depend on the binding/releasing nucleotide, and it is smaller for ADP than for ATP. There is a good agreement, with no adjustable parameters, between the theoretical and experimental results of controlled rotation experiments and stalling experiments, for the range of angles where the data overlap. This agreement is perhaps all the more surprising because it occurs even though the binding and release of fluorescent nucleotides is monitored at single-site occupancy concentrations, whereas the stalling and free rotation experiments have multiple-site occupancy.

  20. Linear shaped charge

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, David; Stofleth, Jerome H.; Saul, Venner W.


    Linear shaped charges are described herein. In a general embodiment, the linear shaped charge has an explosive with an elongated arrowhead-shaped profile. The linear shaped charge also has and an elongated v-shaped liner that is inset into a recess of the explosive. Another linear shaped charge includes an explosive that is shaped as a star-shaped prism. Liners are inset into crevices of the explosive, where the explosive acts as a tamper.

  1. A model for roll stall and the inherent stability modes of low aspect ratio wings at low Reynolds numbers (United States)

    Shields, Matt

    The development of Micro Aerial Vehicles has been hindered by the poor understanding of the aerodynamic loading and stability and control properties of the low Reynolds number regime in which the inherent low aspect ratio (LAR) wings operate. This thesis experimentally evaluates the static and damping aerodynamic stability derivatives to provide a complete aerodynamic model for canonical flat plate wings of aspect ratios near unity at Reynolds numbers under 1 x 105. This permits the complete functionality of the aerodynamic forces and moments to be expressed and the equations of motion to solved, thereby identifying the inherent stability properties of the wing. This provides a basis for characterizing the stability of full vehicles. The influence of the tip vortices during sideslip perturbations is found to induce a loading condition referred to as roll stall, a significant roll moment created by the spanwise induced velocity asymmetry related to the displacement of the vortex cores relative to the wing. Roll stall is manifested by a linearly increasing roll moment with low to moderate angles of attack and a subsequent stall event similar to a lift polar; this behavior is not experienced by conventional (high aspect ratio) wings. The resulting large magnitude of the roll stability derivative, Cl,beta and lack of roll damping, Cl ,rho, create significant modal responses of the lateral state variables; a linear model used to evaluate these modes is shown to accurately reflect the solution obtained by numerically integrating the nonlinear equations. An unstable Dutch roll mode dominates the behavior of the wing for small perturbations from equilibrium, and in the presence of angle of attack oscillations a previously unconsidered coupled mode, referred to as roll resonance, is seen develop and drive the bank angle? away from equilibrium. Roll resonance requires a linear time variant (LTV) model to capture the behavior of the bank angle, which is attributed to the

  2. Spacecraft Charging Technology, 1980 (United States)


    The third Spacecraft Charging Technology Conference proceedings contain 66 papers on the geosynchronous plasma environment, spacecraft modeling, charged particle environment interactions with spacecraft, spacecraft materials characterization, and satellite design and testing. The proceedings is a compilation of the state of the art of spacecraft charging and environmental interaction phenomena.

  3. Exploratory study of the effects of wing-leading-edge modifications on the stall/spin behavior of a light general aviation airplane (United States)


    Configurations with full-span and segmented leading-edge flaps and full-span and segmented leading-edge droop were tested. Studies were conducted with wind-tunnel models, with an outdoor radio-controlled model, and with a full-scale airplane. Results show that wing-leading-edge modifications can produce large effects on stall/spin characteristics, particularly on spin resistance. One outboard wing-leading-edge modification tested significantly improved lateral stability at stall, spin resistance, and developed spin characteristics.

  4. High-temperature order-disorder transitions in the skutterudites CoGe{sub 1.5}Q{sub 1.5} (Q=S, Te)

    Energy Technology Data Exchange (ETDEWEB)

    Kaltzoglou, Andreas; Powell, Anthony V. [Institute of Chemical Sciences and Centre for Advanced Energy Storage and Recovery (CAESAR), Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom); Knight, Kevin S. [ISIS Facility, Rutherford Appleton Laboratory, Didcot, Oxfordshire OX11 0OX (United Kingdom); Vaqueiro, Paz, E-mail: [Institute of Chemical Sciences and Centre for Advanced Energy Storage and Recovery (CAESAR), Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom)


    The temperature dependence of anion ordering in the skutterudites CoGe{sub 1.5}Q{sub 1.5} (Q=S, Te) has been investigated by powder neutron diffraction. Both materials adopt a rhombohedral structure at room temperature (space group R3{sup Macron} ) in which the anions are ordered trans to each other within Ge{sub 2}Q{sub 2} rings. In CoGe{sub 1.5}S{sub 1.5}, anion ordering is preserved up to the melting point of 950 Degree-Sign C. However, rhombohedral CoGe{sub 1.5}Te{sub 1.5} undergoes a phase transition at 610 Degree-Sign C involving a change to cubic symmetry (space group Im3{sup Macron }). In the high-temperature modification, there is a statistical distribution of anions over the available sites within the Ge{sub 2}Te{sub 2} rings. The structural transition involves a reduction in the degree of distortion of the Ge{sub 2}Te{sub 2} rings which progressively transform from a rhombus to a rectangular shape. The effect of this transition on the thermoelectric properties has been investigated. - Graphical abstract: Powder neutron diffraction reveals that the skutterudite CoGe{sub 1.5}Te{sub 1.5} undergoes a phase transition at 610 Degree-Sign C, involving the disordering of the anions within the Ge{sub 2}Te{sub 2} rings. Highlights: Black-Right-Pointing-Pointer CoGe{sub 1.5}S{sub 1.5} retains an ordered skutterudite structure up to 950 Degree-Sign C. Black-Right-Pointing-Pointer CoGe{sub 1.5}Te{sub 1.5} undergoes an order-disorder phase transition at 610 Degree-Sign C. Black-Right-Pointing-Pointer Below 610 Degree-Sign C, anions are arranged trans to each other within Ge{sub 2}Te{sub 2} rings. Black-Right-Pointing-Pointer Above 610 Degree-Sign C, anions are statistically distributed within the Ge{sub 2}Te{sub 2} rings. Black-Right-Pointing-Pointer The effect of the phase transition on the thermal conductivity is discussed.

  5. Charged particle detector

    International Nuclear Information System (INIS)

    Hagen, R.D.


    A device for detecting the emission of charged particles from a specimen is described. The specimen is placed within an accumulator means which statically accumulates any charged particles emitted from the specimen. The accumulator means is pivotally positioned between a first capacitor plate having a positive electrical charge and a second capacitor plate having a negative electrical charge. The accumulator means is attracted to one capacitor plate and repelled from the other capacitor plate by an amount proportional to the amount and intensity of charged particles emitted by the specimen. (auth)

  6. Space Charge Effects

    CERN Document Server

    Ferrario, M.; Palumbo, L.


    The space charge forces are those generated directly by the charge distribution, with the inclusion of the image charges and currents due to the interaction of the beam with a perfectly conducting smooth pipe. Space charge forces are responsible for several unwanted phenomena related to beam dynamics, such as energy loss, shift of the synchronous phase and frequency , shift of the betatron frequencies, and instabilities. We will discuss in this lecture the main feature of space charge effects in high-energy storage rings as well as in low-energy linacs and transport lines.

  7. Developmental validation of QIAGEN Investigator®24plex QS Kit and Investigator®24plex GO! Kit: Two 6-dye multiplex assays for the extended CODIS core loci. (United States)

    Kraemer, Melanie; Prochnow, Anke; Bussmann, Michael; Scherer, Mario; Peist, Ralf; Steffen, Carolyn


    The original CODIS database based on 13 core STR loci has been overwhelmingly successful for matching suspects with evidence. In order to increase the power of discrimination, reduce the possibility of adventitious matches, and expand global data sharing, the CODIS Core Loci Working Group determined the expansion of the CODIS core loci to 20 STR plus three additional "highly recommended" loci (SE33, DY391, Amelogenin) Hares, 2015, 2012 [1,2]. The QIAGEN Investigator 24plex QS and Investigator 24plex GO! Kits are 6-dye multiplex assays that contain all markers of the expanded 23 CODIS core loci along with a unique internal performance control that is co-amplified with the STR markers. The "Quality Sensor" generates additional information for quality control and performance checks. Investigator 24plex QS is designed for purified DNA from casework and reference samples, whereas 24plex GO! is dedicated to direct amplification of reference samples, like blood or buccal cells on FTA or swabs. A developmental validation study was performed on both assays. Here, we report the results of this study which followed the recommendations of the European Network of Forensic Science Institutes (ENFSI) [3] and the Revised Validation Guidelines of the Scientific Working Group on DNA Analysis Methods (SWGDAM) [4]. Data included are for PCR-based procedures e.g. reaction conditions, effects of PCR annealing temperature variations, amplification cycles or cyclers, sensitivity (also in the context of the Quality Sensor), performance with simulated inhibition, stability and efficiency, precision, reproducibility, mixture study, concordance, stutter, species specificity, and case-type samples. The validation results demonstrate that the Investigator 24plex QS and Investigator 24plex GO! Kits are robust and reliable identification assays as required for forensic DNA typing in forensic casework analysis and databasing. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights

  8. Effects of the inlet boundary layer thickness on the flow in an axial compressor (I) : hub corner stall and tip leakage flow

    International Nuclear Information System (INIS)

    Choi, Min Suk; Baek, Je Hyun; Park, Jun Young


    A three-dimensional computation was conducted to understand effects of the inlet boundary layer thickness on the internal flow in a low-speed axial compressor operating at the design condition(φ=85%) and near stall condition(φ=65%). At the design condition, the flows in the axial compressor show, independent of the inlet boundary layer thickness, similar characteristics such as the pressure distribution, size of the hub corner-stall, tip leakage flow trajectory, limiting streamlines on the blade suction surface, etc. However, as the load is increased, the hub corner-stall grows to make a large separation region at the junction of the hub and suction surface for the inlet condition with thick boundary layers at the hub and casing. Moreover, the tip leakage flow is more vortical than that observed in case of the thin inlet boundary layer and has the critical point where the trajectory of the tip leakage flow is abruptly turned into the downstream. For the inlet condition with thin boundary layers, the hub corner-stall is diminished so it is indistinguishable from the wake. The tip leakage flow leans to the leading edge more than at the design condition but has no critical point. In addition to these, the severe reverse flow, induced by both boundary layer on the blade surface and the tip leakage flow, can be found to act as the blockage of flows near the casing, resulting in heavy loss

  9. Stall/surge dynamics of a multi-stage air compressor in response to a load transient of a hybrid solid oxide fuel cell-gas turbine system (United States)

    Azizi, Mohammad Ali; Brouwer, Jacob


    A better understanding of turbulent unsteady flows in gas turbine systems is necessary to design and control compressors for hybrid fuel cell-gas turbine systems. Compressor stall/surge analysis for a 4 MW hybrid solid oxide fuel cell-gas turbine system for locomotive applications is performed based upon a 1.7 MW multi-stage air compressor. Control strategies are applied to prevent operation of the hybrid SOFC-GT beyond the stall/surge lines of the compressor. Computational fluid dynamics tools are used to simulate the flow distribution and instabilities near the stall/surge line. The results show that a 1.7 MW system compressor like that of a Kawasaki gas turbine is an appropriate choice among the industrial compressors to be used in a 4 MW locomotive SOFC-GT with topping cycle design. The multi-stage radial design of the compressor enhances the ability of the compressor to maintain air flow rate during transient step-load changes. These transient step-load changes are exhibited in many potential applications for SOFC/GT systems. The compressor provides sustained air flow rate during the mild stall/surge event that occurs due to the transient step-load change that is applied, indicating that this type of compressor is well-suited for this hybrid application.

  10. Analysis of the Unsteady Flow Field in a Centrifugal Compressor from Peak Efficiency to Near Stall with Full-Annulus Simulations

    Directory of Open Access Journals (Sweden)

    Yannick Bousquet


    Full Text Available This study concerns a 2.5 pressure ratio centrifugal compressor stage consisting of a splittered unshrouded impeller and a vaned diffuser. The aim of this paper is to investigate the modifications of the flow structure when the operating point moves from peak efficiency to near stall. The investigations are based on the results of unsteady three-dimensional simulations, in a calculation domain comprising all the blade. A detailed analysis is given in the impeller inducer and in the vaned diffuser entry region through time-averaged and unsteady flow field. In the impeller inducer, this study demonstrates that the mass flow reduction from peak efficiency to near stall leads to intensification of the secondary flow effects. The low momentum fluid accumulated near the shroud interacts with the main flow through a shear layer zone. At near stall condition, the interface between the two flow structures becomes unstable leading to vortices development. In the diffuser entry region, by reducing the mass flow, the high incidence angle from the impeller exit induces a separation on the diffuser vane suction side. At near stall operating point, vorticity from the separation is shed into vortex cores which are periodically formed and convected downstream along the suction side.

  11. Divulgación on-line de los códigos de buen gobierno en las IES y su determinación para el posicionamiento en el ranking QS


    Méndez Beltrán, Jairo Andrés


    Dado el interés que se presenta con los temas de gobierno corporativo, este trabajo busca describir si la divulgación on-line de los contenidos de los códigos de buen gobierno, es determinante en el posicionamiento que tienen las Instituciones de Educación Superior (IES) en el ranking QS. Partiendo de una muestra de 20 IES, se recolectaron un conjunto de datos dicotómicos para 30 variables independientes y se relacionaron con la variable dependiente denominada posicionamiento en el ranking. A...

  12. Contractor Software Charges

    National Research Council Canada - National Science Library

    Granetto, Paul


    .... Examples of computer software costs that contractors charge through indirect rates are material management systems, security systems, labor accounting systems, and computer-aided design and manufacturing...

  13. Charge Screening in a Charged Condensate

    International Nuclear Information System (INIS)

    Gabadadze, Gregory; Rosen, Rachel A.


    We consider a highly dense system of helium-4 nuclei and electrons in which the helium-4 nuclei have condensed. We present the condensation mechanism in the framework of low energy effective field theory and discuss the screening of electric charge in the condensate.

  14. Surface Charging and Points of Zero Charge

    CERN Document Server

    Kosmulski, Marek


    Presents Points of Zero Charge data on well-defined specimen of materials sorted by trademark, manufacturer, and location. This text emphasizes the comparison between particular results obtained for different portions of the same or very similar material and synthesizes the information published in research reports over the past few decades

  15. Unilateral CHARGE association

    NARCIS (Netherlands)

    Trip, J; van Stuijvenberg, M; Dikkers, FG; Pijnenburg, MWH

    A case with a predominantly unilateral CHARGE association is reported. The CHARGE association refers to a combination of congenital malformations. This boy had left-sided anomalies consisting of choanal atresia. coloboma and peripheral facial palsy. The infant had a frontal encephalocele. an anomaly

  16. Suppression of inducer stall based on inlet recirculation in a centrifugal impeller. 1st Report. Improvement in stall limit by ring groove arrangement; Enshin haneguruma iriguchi junkanryu ni yoru inducer shissoku no yokusei. 1. kanjoko ni yoru shissoku genkai no kaizen

    Energy Technology Data Exchange (ETDEWEB)

    Ueki, H.; Ishida, M.; Sakaguchi, D.; Sun, Z. [Nagasaki University, Nagasaki (Japan). Faculty of Engineering


    A ring groove arrangement is proposed to suppress unstable flow or surge in a centrifugal blower. The ring groove arrangement connects the upstream position of impeller inlet and the inducer throat tip through a bypass. The recirculation flow 'vas formed by the pressure difference between the two positions, and the recirculation flow rate was changed by increasing the ring groove widths. The inlet recirculation results in a decrease in the flow rate of unstable flow inception, and an up to 800 improvement in stall limit was obtained by the ring groove arrangement at a small expense of the delivery pressure drop. The improvement of stall limit in the present experiment seems to be mainly due to decrease in flow incidence based on the inlet recirculation flow. Tre flow incidence decreases more as the recirculation flow rate increases, thus resulting in a larger improvement in stall limit. (author)

  17. Charge Storage, Conductivity and Charge Profiles of Insulators As Related to Spacecraft Charging


    Dennison, JR; Frederickson, A. R.; Swaminathan, Prasanna


    Dissipation of charges built up near the surface of insulators due to space environment interaction is central to understanding spacecraft charging. Conductivity of insulating materials is key to determine how accumulated charge will distribute across the spacecraft and how rapidly charge imbalance will dissipate. To understand these processes requires knowledge of how charge is deposited within the insulator, the mechanisms for charge trapping and charge transport within the insulator, and h...

  18. Charge gradient microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Roelofs, Andreas; Hong, Seungbum


    A method for rapid imaging of a material specimen includes positioning a tip to contact the material specimen, and applying a force to a surface of the material specimen via the tip. In addition, the method includes moving the tip across the surface of the material specimen while removing electrical charge therefrom, generating a signal produced by contact between the tip and the surface, and detecting, based on the data, the removed electrical charge induced through the tip during movement of the tip across the surface. The method further includes measuring the detected electrical charge.

  19. Water Quality Protection Charges (United States)

    Montgomery County of Maryland — The Water Quality Protection Charge (WQPC) is a line item on your property tax bill. WQPC funds many of the County's clean water initiatives including: • Restoration...

  20. Space-Charge Effect

    CERN Document Server

    Chauvin, N.


    First, this chapter introduces the expressions for the electric and magnetic space-charge internal fields and forces induced by high-intensity beams. Then, the root-mean-square equation with space charge is derived and discussed. In the third section, the one-dimensional Child-Langmuir law, which gives the maximum current density that can be extracted from an ion source, is exposed. Space-charge compensation can occur in the low-energy beam transport lines (located after the ion source). This phenomenon, which counteracts the spacecharge defocusing effect, is explained and its main parameters are presented. The fifth section presents an overview of the principal methods to perform beam dynamics numerical simulations. An example of a particles-in-cells code, SolMaxP, which takes into account space-charge compensation, is given. Finally, beam dynamics simulation results obtained with this code in the case of the IFMIF injector are presented.

  1. Electric charge quantization

    International Nuclear Information System (INIS)

    Foot, R.; Lew, H.; Volkas, R.R.


    Experimentally it has been known for a long time that the electric charges of the observed particles appear to be quantized. An approach to understanding electric charge quantization that can be used for gauge theories with explicit U(1) factors - such as the standard model and its variants - is pedagogically reviewed and discussed in this article. This approach used the allowed invariances of the Lagrangian and their associated anomaly cancellation equations. It is demonstrated that charge may be de-quantized in the three-generation standard model with massless neutrinos, because differences in family-lepton-numbers are anomaly-free. The relevant experimental limits are also reviewed. This approach to charge quantization suggests that the minimal standard model should be extended so that family-lepton-number differences are explicitly broken. Some candidate extensions such as the minimal standard model augmented by Majorana right-handed neutrinos are also briefly discussed. 30 refs

  2. EV Charging Infrastructure Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Karner, Donald [Electric Transportation Inc., Rogers, AR (United States); Garetson, Thomas [Electric Transportation Inc., Rogers, AR (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States)


    As highlighted in the U.S. Department of Energy’s EV Everywhere Grand Challenge, vehicle technology is advancing toward an objective to “… produce plug-in electric vehicles that are as affordable and convenient for the average American family as today’s gasoline-powered vehicles …” [1] by developing more efficient drivetrains, greater battery energy storage per dollar, and lighter-weight vehicle components and construction. With this technology advancement and improved vehicle performance, the objective for charging infrastructure is to promote vehicle adoption and maximize the number of electric miles driven. The EV Everywhere Charging Infrastructure Roadmap (hereafter referred to as Roadmap) looks forward and assumes that the technical challenges and vehicle performance improvements set forth in the EV Everywhere Grand Challenge will be met. The Roadmap identifies and prioritizes deployment of charging infrastructure in support of this charging infrastructure objective for the EV Everywhere Grand Challenge

  3. Electric Vehicle Charging Modeling


    Grahn, Pia


    With an electrified passenger transportation fleet, carbon dioxide emissions could be reduced significantly depending on the electric power production mix. Increased electric power consumption due to electric vehicle charging demands of electric vehicle fleets may be met by increased amount of renewable power production in the electrical systems. With electric vehicle fleets in the transportation system there is a need for establishing an electric vehicle charging infrastructure that distribu...

  4. Operating systems: Internals and design principles, 5th ed. William Stallings : Prentice Hall, 2005. ISBN: 0-13-147954-7


    Molinari, Lía Hebe


    As a professor of the Operating Systems subject, I can say that for many years the book “Operating Systems Concepts” by Avi Silberschatz et al. was considered as the unquestionable number one in the subject’s bibliography. The book we are talking about now, the new edition of “Operating Systems” by William Stallings, is thought to be the possible replacement of the first one.

  5. The elastic transfer model of angular rate modulation in F1-ATPase stalling and controlled rotation experiments (United States)

    Volkán-Kacsó, S.


    The recent experimental, theoretical and computational advances in the field of F1-ATPase single-molecule microscopy are briefly surveyed. The role of theory is revealed in the statistical analysis, interpretation and prediction of single-molecule experimental trajectories, and in linking them with atomistic simulations. In particular, a theoretical model of elastically coupled molecular group transfer is reviewed and a detailed method for its application in stalling and controlled rotation experiments is provided. It is shown how the model can predict, using previous experiments, the rates of ligand binding/release processes (steps) and their exponential dependence on rotor angle in these experiments. The concept of Brønsted slopes is reviewed in the context of the single-molecule experiments, and the rate versus rotor angle relations are explained using the elastic model. These experimental data are treated in terms of the effect of thermodynamic driving forces on the rates assuming that the rotor shaft is elastically coupled to stator ring subunits in which the steps occur. In the application of the group transfer model on an extended angular range processes leading up to the transfer are discussed. Implications for large-scale atomistic simulation are suggested for the treatment of torque-generating steps.

  6. Exploiting translational stalling peptides in an effort to extend azithromycin interaction within the prokaryotic ribosome nascent peptide exit tunnel. (United States)

    Washington, Arren Z; Tapadar, Subhasish; George, Alex; Oyelere, Adegboyega K


    The ribosome is the primary protein synthesis machine in the cell and is a target for treatment of a variety of diseases including bacterial infection and cancer. The ribosomal peptide exit tunnel, the route of egress for the nascent peptide, is an inviting site for drug design. Toward a rational engagement of the nascent peptide components for the design of small molecule inhibitors of ribosome function, we designed and disclosed herein a set of N-10 indole functionalized azithromycin analogs. The indole moiety of these compounds is designed to mimic the translation stalling interaction of SecM W155 side-chain with the prokaryotic (Escherichia coli) ribosome A751 residue. Many of these N-10 functionalized compounds have enhanced translation inhibition activities against E. coli ribosome relative to azithromycin while a subset inhibited the growth of representative susceptible bacteria strains to about the same extent as azithromycin. Moreover, the inclusion of bovine serum in the bacterial growth media enhanced the anti-bacterial potency of the N-10 functionalized azithromycin analogs by as high as 10-fold. Published by Elsevier Ltd.

  7. A study of the drooped leading edge airfoil. [on wind tunnel models to reduce spin entry after stall (United States)

    Anderson, J. D., Jr.; Barlow, J. B.


    Wind tunnel tests were conducted to examine various aspects of the drooped-leading edge airfoil which reduces the tendency for an airplane to enter a spin after stall occurs. Three baseline models were used for tests of two dimensional models: NACA 0015, 0014.6, and 0014.2. The 14.6% and 14.2% models were derived from NACA 0015 sections by increasing the chord and matching the profiles aft section. Force, balance data (lift, drag, pitching moment) were obtained for each model at a free-steam Reynold's number of 2.66 x 10 to the 6th power/m. In addition, oil flow visualization tests were performed at various angles of attack. An existing NACA 64 sub 1 A211 airfoil was used in a second series of tests. The leading edge flap was segmented in three parts which allowed various baseline/drooped leading edge configurations to be tested. Force balance and flow visualization tests were completer at chord Renolds numbers of 0.44 x 10 to the 6th power, 1.4 x 10 to the 6th power, and 2.11 x 10 to the 6th power. Test results are included.

  8. Using Nature-Based Rehabilitation to Restart a Stalled Process of Rehabilitation in Individuals with Stress-Related Mental Illness

    Directory of Open Access Journals (Sweden)

    Eva Sahlin


    Full Text Available After a period of decrease, sick leave in Sweden due to psychiatric diagnoses is on the increase. The lack of established rehabilitation programmes for patients with stress-related mental disorders (SRMD has opened up for the use of garden/nature in a multimodal rehabilitation context (Nature-Based Rehabilitation, NBR. Region Västra Götaland (VGR started an NBR to offer additional rehabilitation for its employees on long-term sick leave due to SRMD, where initial care had not been sufficient. The aim was to explore whether the mental health and well-being of NBR participants had improved at the end of the NBR and at three follow-ups, and to explore the development of sick leave and health care utilization according to the NBR model (n = 57 and an occupational health service (OHS model (n = 45. Self-assessment instruments for measuring burnout, depression, anxiety and wellbeing, and data from regional and national registers were used. Results showed decreased scores on burnout, depression and anxiety, and increased well-being scores and significantly reduced health care utilization in the NBR group. A large movement from ordinary sickness benefit to rehabilitation benefit was observed, which was not observed in the OHS group. The two groups were in different rehabilitation phases, which limited comparisons. The results point to beneficial effects of using NBR for this patient group and for enhancing a stalled rehabilitation process.

  9. Investigating dynamic stall, 3-D and rotational effects on wind turbine blades by means of an unsteady quasi-3D Navier-Stokes solver

    Energy Technology Data Exchange (ETDEWEB)

    Chaviaropoulos, P.K. [CRES-Center for Renewable Energy Sources, Pikermi Attiki (Greece)


    The blade element codes provide surprisingly accurate predictions of the aerodynamic loads provided that they are `fed` with proper lift and drag - incidence curves for the profiles mounted on the rotor blades. The evident question is how one can obtain such data. It is common experience that the use of the mostly available steady two-dimensional profile data may lead to serious discrepancies between measured and simulated loads. Although several correction techniques have been proposed as a remedy during the last years, from simplified dynamic stall models suitably tuned for wind turbines to 3-D correction schemes for profile data, the problem is by no means over-passed. Especially for the three-dimensional effects it seems that part of the difficulty is due to our limited understanding of the physical mechanism which is responsible for the extra loading of the inner part of the blades. Recognizing the importance of the above aspects two relevant Joule projects have been launched, the concluded `Dynamic Stall and 3-D Effects` JOU2-CT93-0345 and the ongoing `VISCWIND` JOR3-CT95-0007 project. Part of the activities in the first and all the activities in the second project are devoted to the identification and quantification of the dynamic stall and three-dimensional effects experienced by the wind turbine blades using Navier-Stokes computations. The contribution of CRES in these two projects is briefly presented in this paper. (EG)

  10. Caracterização do microambiente em secção transversal de um galpão do tipo "free-stall" orientado na direção norte-sul Environment characterization in transversal direction in a free-stall housing oriented to north-south direction

    Directory of Open Access Journals (Sweden)

    Alessandro T. Campos


    Full Text Available O trabalho teve o objetivo de caracterizar o microambiente climático das baias de um galpão de confinamento para gado leiteiro, modelo "free-stall", no sentido transversal da instalação. O "free-stall" é orientado na direção norte-sul, localizado em Marechal Cândido Rondon, região Oeste do Paraná, com capacidade para abrigar 40 vacas em lactação (40 baias. Visando à determinação do Índice de Temperatura do Globo e Umidade (ITGU e da Carga Térmica de Radiação (CTR, foram instalados quatro globos negros, no centro de baias dispostas no sent ido transversal, dispondo dois globos no lado oeste e dois globos no lado leste (separados pelo corredor de alimentação. Lateralmente ao galpão, no lado leste, havia vegetação a 4 m da instalação, que promovia sombreamento nas primeiras horas do dia. Pode-se concluir que, nas primeiras horas do dia, não há diferença significativa entre os valores de ITGU e CTR encontrados, indicando que o sombreamento, devido à vegetação, foi capaz de amenizar os efeitos da radiação solar. Às 17 h 30 min, verificou-se que há ocorrência de maiores valores, tanto de ITGU quanto de CTR, nas baias localizadas no lado oeste do "free-stall".This work aimed to characterize the microclimatic conditions of the stalls of a free-stall model confinement building for dairy cattle in the transversal direction of the installation. Free-stall building was oriented to north-south direction, located in Marechal Cândido Rondon, west of Paraná State -Brazil, with a capacity of 40 dairy cows (40 stalls. In order to determine the Black-Globe-Humidity Index (BGHI and Radiant Heat Load (RHL, four black globes were installed in the center of stalls disposed in the transversal direction, disposing two globes in the west side and two globes in the east side (separated by the feed alley. At the building sidelong, east side, there was a four meter distant vegetation, that promoted shading in the first hours of the day

  11. Perdas econômicas ocasionadas pelas enfermidades podais em vacas leiteiras confinadas em sistema free stall Economic losses caused by sequels of lameness in free-stall-housed dairy cows

    Directory of Open Access Journals (Sweden)

    R.C. Souza


    Full Text Available Avaliaram-se 55 casos clínicos de manqueira em um rebanho de 100 vacas em lactação confinadas em sistema de free stall, durante um ano. As afecções mais observadas foram abscessos de sola e talão, úlcera de sola e dermatite digital que representaram 87,3% (48/55 das ocorrências. O tratamento empregado mostrou-se satisfatório com recuperação de todos os animais tratados com 24,5 dias, em média, sem ocorrência de descarte. O custo com tratamento e redução na produção de leite foi de US$95.80/vaca, o que representou US$52.69 por vaca alojada/ano. Quando se computaram as perdas reprodutivas e com mastite, obtiveram-se US$227.94 adicionais em vaca com problema de manqueira. O custo adicional anual total no rebanho decorrente de seqüelas de manqueira foi de US$12,536.70, que representou US$125.36 por vaca alojada/ano. O período de serviço e o número de serviços por concepção em vacas com problemas de manqueira e normais foram 266 e 200,5 dias e 4,3 e 3,3 serviços, respectivamente. As incidências de mastite e metrite na mesma ordem de citação anterior foram 60% e 25% e 29% e 12,5%.Fifty-five clinical cases of lameness were evaluated in 100 lactating cows housed in a free-stall system during one year. The most observed affections were sole and heel abscesses, sole ulcers and digital dermatitis that accounted for 87.3% (48/55 of the occurrences. The treated cows showed satisfactory recovery (24.5 average days without culling. The total individual cost including treatment and reduction of milk production was US$95.80/cow or US$52.69 per housed cow/year. When reproductive losses and mastitis were considered an additional cost of US$227.94 per lameness cow was estimated. The total additional annual cost from sequels of lameness was US$12.536.70 or US$152.36 per housed cow/year. The number of days open and the number of services per conception in lameness and normal cows were, respectively, 266 and 200.5 days and 4.3 and 3

  12. Charge transfer in astrophysical nebulae

    International Nuclear Information System (INIS)

    Shields, G.A.


    Charge transfer has become a standard ingredient in models of ionized nebulae, supernovae remnants and active galactic nuclei. Charge transfer rate coefficients and the physics of ionized nebulae are considered. Charge transfer is applied to the ionization structure and line emission of ionized nebulae. Photoionized nebulae observations are used to test theoretical predictions of charge transfer rates. (author)

  13. Electric vehicle battery charging controller

    DEFF Research Database (Denmark)


    to a battery management system in the electric vehicle to charge a battery therein, a first communication unit for receiving a charging message via a communication network, and a control unit for controlling a charging current provided from the charge source to the electric vehicle, the controlling at least...

  14. Dispersion and space charge

    International Nuclear Information System (INIS)

    Venturini, M.; Kishek, R.A.; Reiser, M.


    The presence of space charge affects the value of the dispersion function. On the other hand dispersion has a role in shaping the beam distribution and therefore in determining the resulting forces due to space charge. In this paper we present a framework where the interplay between space charge and dispersion for a continuous beam can be simultaneously treated. We revise the derivation of a new set of rms envelope-dispersion equations we have recently proposed in [1]. The new equations generalize the standard rms envelope equations currently used for matching to the case where bends and a longitudinal momentum spread are present. We report a comparison between the solutions of the rms envelope-dispersion equations and the results obtained using WARP, a Particle in Cell (PIC) code, in the modeling of the Maryland Electron Ring. copyright 1998 American Institute of Physics

  15. Dispersion and space charge

    Energy Technology Data Exchange (ETDEWEB)

    Venturini, M. [Department of Physics and Institute for Plasma Research, University of Maryland, College Park, Maryland 20742 (United States); Kishek, R.A.; Reiser, M. [Department of Electrical Engeneering and Institute for Plasma Research, University of Maryland, College Park, Maryland 20742 (United States)


    The presence of space charge affects the value of the dispersion function. On the other hand dispersion has a role in shaping the beam distribution and therefore in determining the resulting forces due to space charge. In this paper we present a framework where the interplay between space charge and dispersion for a continuous beam can be simultaneously treated. We revise the derivation of a new set of rms envelope-dispersion equations we have recently proposed in [1]. The new equations generalize the standard rms envelope equations currently used for matching to the case where bends and a longitudinal momentum spread are present. We report a comparison between the solutions of the rms envelope-dispersion equations and the results obtained using WARP, a Particle in Cell (PIC) code, in the modeling of the Maryland Electron Ring. {copyright} {ital 1998 American Institute of Physics.}

  16. Dispersion and space charge

    International Nuclear Information System (INIS)

    Venturini, Marco; Kishek, Rami A.; Reiser, Martin


    The presence of space charge affects the value of the dispersion function. On the other hand dispersion has a role in shaping the beam distribution and therefore in determining the resulting forces due to space charge. In this paper we present a framework where the interplay between space charge and dispersion for a continuous beam can be simultaneously treated. We revise the derivation of a new set of rms envelope-dispersion equations we have recently proposed. The new equations generalize the standard rms envelope equations currently used for matching to the case where bends and a longitudinal momentum spread are present. We report a comparison between the solutions of the rms envelope-dispersion equations and the results obtained using WARP, a Particle in Cell (PIC) code, in the modeling of the Maryland Electron Ring

  17. Sources for charged particles

    International Nuclear Information System (INIS)

    Arianer, J.


    This document is a basic course on charged particle sources for post-graduate students and thematic schools on large facilities and accelerator physics. A simple but precise description of the creation and the emission of charged particles is presented. This course relies on every year upgraded reference documents. Following relevant topics are considered: electronic emission processes, technological and practical considerations on electron guns, positron sources, production of neutral atoms, ionization, plasma and discharge, different types of positive and negative ion sources, polarized particle sources, materials for the construction of ion sources, low energy beam production and transport. (N.T.)

  18. Charged conformal Killing spinors

    Energy Technology Data Exchange (ETDEWEB)

    Lischewski, Andree, E-mail: [Humboldt-Universität zu Berlin, Institut für Mathematik, Rudower Chaussee 25, Room 1.310, D12489 Berlin (Germany)


    We study the twistor equation on pseudo-Riemannian Spin{sup c}-manifolds whose solutions we call charged conformal Killing spinors (CCKSs). We derive several integrability conditions for the existence of CCKS and study their relations to spinor bilinears. A construction principle for Lorentzian manifolds admitting CCKS with nontrivial charge starting from CR-geometry is presented. We obtain a partial classification result in the Lorentzian case under the additional assumption that the associated Dirac current is normal conformal and complete the classification of manifolds admitting CCKS in all dimensions and signatures ≤5 which has recently been initiated in the study of supersymmetric field theories on curved space.

  19. A Charge Parity Ammeter (United States)

    Lambert, Nicholas J.; Edwards, Megan; Ciccarelli, Chiara; Ferguson, Andrew J.


    A metallic double-dot is measured with radio frequency reflectometry. Changes in the total electron number of the double-dot are determined via single electron tunnelling contributions to the complex electrical impedance. Electron counting experiments are performed by monitoring the impedance, demonstrating operation of a single electron ammeter without the need for external charge detection.

  20. Salmonella Taking Charge


    Weigele, Bethany A.; Alto, Neal M.


    Pathogens develop creative ways to undermine host defenses. In this issue of Cell Host & Microbe, Bakowski et al. (2010) have unveiled a mechanism by which Salmonella evades lysosomal fusion by using a bacterial protein, SopB, that depletes the phagosomal membrane of negative charge.

  1. Charged Particle Optics Theory

    Czech Academy of Sciences Publication Activity Database

    Hawkes, P. W.; Lencová, Bohumila

    -, č. 6 (2006), s. 6-8 Grant - others:EC 5RP(XE) G5RD-CT-2000-00344 Institutional research plan: CEZ:AV0Z20650511 Keywords : optics of charged particles * design of ion lithography system * spot profile * the finite element method Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

  2. Charged particle beams

    CERN Document Server

    Humphries, Stanley


    Detailed enough for a text and sufficiently comprehensive for a reference, this volume addresses topics vital to understanding high-power accelerators and high-brightness-charged particle beams. Subjects include stochastic cooling, high-brightness injectors, and the free electron laser. Humphries provides students with the critical skills necessary for the problem-solving insights unique to collective physics problems. 1990 edition.

  3. Charge oscillations in orbitrons

    International Nuclear Information System (INIS)

    Porto, M.; Gomes, L.C.


    A statistical model for the electron distribution in orbitrons is constructed where the effect of the end plates is considered. A comparison is made with the measured density of charge. The electromagnetic oscillations generated by orbitrons are calculated as pressure waves and the results obtained are compared with the data. (Author) [pt

  4. Measurement of Neutrino Induced, Charged Current, Charged Pion Production

    Energy Technology Data Exchange (ETDEWEB)

    Wilking, Michael Joseph [Univ. of Colorado, Boulder, CO (United States)


    Neutrinos are among the least understood particles in the standard model of particle physics. At neutrino energies in the 1 GeV range, neutrino properties are typically determined by observing the outgoing charged lepton produced in a charged current quasi-elastic interactions. The largest charged current background to these measurements comes from charged current pion production interactions, for which there is very little available data.

  5. The quasilocalized charge approximation

    International Nuclear Information System (INIS)

    Kalman, G J; Golden, K I; Donko, Z; Hartmann, P


    The quasilocalized charge approximation (QLCA) has been used for some time as a formalism for the calculation of the dielectric response and for determining the collective mode dispersion in strongly coupled Coulomb and Yukawa liquids. The approach is based on a microscopic model in which the charges are quasilocalized on a short-time scale in local potential fluctuations. We review the conceptual basis and theoretical structure of the QLC approach and together with recent results from molecular dynamics simulations that corroborate and quantify the theoretical concepts. We also summarize the major applications of the QLCA to various physical systems, combined with the corresponding results of the molecular dynamics simulations and point out the general agreement and instances of disagreement between the two

  6. High Voltage Charge Pump

    KAUST Repository

    Emira, Ahmed A.


    Various embodiments of a high voltage charge pump are described. One embodiment is a charge pump circuit that comprises a plurality of switching stages each including a clock input, a clock input inverse, a clock output, and a clock output inverse. The circuit further comprises a plurality of pumping capacitors, wherein one or more pumping capacitors are coupled to a corresponding switching stage. The circuit also comprises a maximum selection circuit coupled to a last switching stage among the plurality of switching stages, the maximum selection circuit configured to filter noise on the output clock and the output clock inverse of the last switching stage, the maximum selection circuit further configured to generate a DC output voltage based on the output clock and the output clock inverse of the last switching stage.

  7. Interaction between heterogeneously charged surfaces: surface patches and charge modulation. (United States)

    Ben-Yaakov, Dan; Andelman, David; Diamant, Haim


    When solid surfaces are immersed in aqueous solutions, some of their charges can dissociate and leave behind charged patches on the surface. Although the charges are distributed heterogeneously on the surface, most of the theoretical models treat them as homogeneous. For overall non-neutral surfaces, the assumption of surface charge homogeneity is rather reasonable since the leading terms of two such interacting surfaces depend on the nonzero average charge. However, for overall neutral surfaces the nature of the surface charge distribution is crucial in determining the intersurface interaction. In the present work we study the interaction between two charged surfaces across an aqueous solution for several charge distributions. The analysis is preformed within the framework of the linearized Poisson-Boltzmann theory. For periodic charge distributions the interaction is found to be repulsive at small separations, unless the two surface distributions are completely out-of-phase with respect to each other. For quenched random charge distributions we find that due to the presence of the ionic solution in between the surfaces, the intersurface repulsion dominates over the attraction in the linear regime of the Poisson-Boltzmann theory. The effect of quenched charge heterogeneity is found to be particularly substantial in the case of large charged domains.

  8. Charged particle analyzer PLAZMAG

    International Nuclear Information System (INIS)

    Apathy, Istvan; Endroeczy, Gabor; Szemerey, Istvan; Szendroe, Sandor


    The scientific task of the charged particle analyzer PLAZMAG, a part of the VEGA space probe, and the physical background of the measurements are described. The sensor of the device face the Sun and the comet Halley measuring the energy and mass spectrum of ion and electron components of energies lower than 25 keV. The tasks of the individual electronic parts, the design aspects and the modes of operation in different phases of the flight are dealt with. (author)

  9. Hidden charged dark matter

    International Nuclear Information System (INIS)

    Feng, Jonathan L.; Kaplinghat, Manoj; Tu, Huitzu; Yu, Hai-Bo


    Can dark matter be stabilized by charge conservation, just as the electron is in the standard model? We examine the possibility that dark matter is hidden, that is, neutral under all standard model gauge interactions, but charged under an exact (\\rm U)(1) gauge symmetry of the hidden sector. Such candidates are predicted in WIMPless models, supersymmetric models in which hidden dark matter has the desired thermal relic density for a wide range of masses. Hidden charged dark matter has many novel properties not shared by neutral dark matter: (1) bound state formation and Sommerfeld-enhanced annihilation after chemical freeze out may reduce its relic density, (2) similar effects greatly enhance dark matter annihilation in protohalos at redshifts of z ∼ 30, (3) Compton scattering off hidden photons delays kinetic decoupling, suppressing small scale structure, and (4) Rutherford scattering makes such dark matter self-interacting and collisional, potentially impacting properties of the Bullet Cluster and the observed morphology of galactic halos. We analyze all of these effects in a WIMPless model in which the hidden sector is a simplified version of the minimal supersymmetric standard model and the dark matter is a hidden sector stau. We find that charged hidden dark matter is viable and consistent with the correct relic density for reasonable model parameters and dark matter masses in the range 1 GeV ∼ X ∼< 10 TeV. At the same time, in the preferred range of parameters, this model predicts cores in the dark matter halos of small galaxies and other halo properties that may be within the reach of future observations. These models therefore provide a viable and well-motivated framework for collisional dark matter with Sommerfeld enhancement, with novel implications for astrophysics and dark matter searches

  10. [Management of the dry and transition periods of dairy cattle in free stall housing systems in Lower Saxony. Part 1: Farm management. Teil 1: Betriebsmanagement]. (United States)

    Oetting-Neumann, Pamela; Hoedemaker, Martina


    Describing husbandry and management of dairy cows during the dry and transition periods on farms of different sizes in Lower Saxony, Germany. A total of 51 dairy farms were visited and asked via questionnaire about the husbandry and management in the following categories: general operating data, stable and husbandry of milking cows, dry cows, transition cows and the youngstock, pasture management, feeding, health data and prophylactic treatments. In addition, during a farm inspection, data on cow comfort were collected. German Holstein was the predominant breed on the dairy farms. Most cattle were kept in three-rowed free-stall housing systems (74%) with straw bedding (47%) without division in productivity groups (59%). The dry cows were most frequently separated in two groups (68%) in free-stall housing systems (68%). The heifers were similarly mainly kept in free-stall housing systems (67%) and were mostly separated according to their reproductive status (74%). On 29% of the farms, pasture grazing was not practiced at any time. On 80% of the farms, cows were fed a mixed ration with computerized concentrate supplementation and on 68% of the farms biphasic dry cow diets were used. The most frequently stated health problems were of the limb and claw (61%). Prophylaxis of ketosis was practiced on 21% of the farms and milk-fever prophylaxis on 12% of the farms, both for each individual cow around calving. Husbandry and management on farms differ widely and are still in need of optimization with respect to barn concepts, implementation of production groups and feeding, as well as veterinary consultation with respect to health problems and prophylactic measures.

  11. Jordan's 2002 to 2012 Fertility Stall and Parallel USAID Investments in Family Planning: Lessons From an Assessment to Guide Future Programming. (United States)

    Spindler, Esther; Bitar, Nisreen; Solo, Julie; Menstell, Elizabeth; Shattuck, Dominick


    Health practitioners, researchers, and donors are stumped about Jordan's stalled fertility rate, which has stagnated between 3.7 and 3.5 children per woman from 2002 to 2012, above the national replacement level of 2.1. This stall paralleled United States Agency for International Development (USAID) funding investments in family planning in Jordan, triggering an assessment of USAID family planning programming in Jordan. This article describes the methods, results, and implications of the programmatic assessment. Methods included an extensive desk review of USAID programs in Jordan and 69 interviews with reproductive health stakeholders. We explored reasons for fertility stagnation in Jordan's total fertility rate (TFR) and assessed the effects of USAID programming on family planning outcomes over the same time period. The assessment results suggest that the increased use of less effective methods, in particular withdrawal and condoms, are contributing to Jordan's TFR stall. Jordan's limited method mix, combined with strong sociocultural determinants around reproduction and fertility desires, have contributed to low contraceptive effectiveness in Jordan. Over the same time period, USAID contributions toward increasing family planning access and use, largely focused on service delivery programs, were extensive. Examples of effective initiatives, among others, include task shifting of IUD insertion services to midwives due to a shortage of female physicians. However, key challenges to improved use of family planning services include limited government investments in family planning programs, influential service provider behaviors and biases that limit informed counseling and choice, pervasive strong social norms of family size and fertility, and limited availability of different contraceptive methods. In contexts where sociocultural norms and a limited method mix are the dominant barriers toward improved family planning use, increased national government investments

  12. Search for fractional charge

    International Nuclear Information System (INIS)

    Turner, R.E.


    A search was made for fractional charges of the form Z plus two-thirds e, where Z is an integer. It was assumed that the charges exist in natural form bound with other fractional charges in neutral molecules. It was further assumed that these neutral molecules are present in air. Two concentration schemes were employed. One sample was derived from the waste gases from a xenon distillation plant. This assumes that high mass, low vapor pressure components of air are concentrated along with the xenon. The second sample involved ionizing air, allowing a brief recombination period, and then collecting residual ions on the surface of titanium discs. Both samples were analyzed at the University of Rochester in a system using a tandem Van de Graff to accelerate particles through an essentially electrostatic beam handling system. The detector system employed both a Time of Flight and an energy-sensitive gas ionization detector. In the most sensitive mode of analysis, a gas absorber was inserted in the beam path to block the intense background. The presence of an absorber limited the search to highly penetrating particles. Effectively, this limited the search to particles with low Z and masses greater than roughly fifty GeV. The final sensitivities attained were on the order of 1 x 10 -20 for the ionized air sample and 1 x 10 -21 for the gas sample. A discussion of the caveats that could reduce the actual level of sensitivity is included

  13. High-speed PIV applied to the wake of the NASA CRM model in ETW at high Re-number stall conditions for sub- and transonic speeds


    Konrath, Robert; Geisler, Reinhard; Otter, Dirk; Philipp, Florian; Ehlers, Hauke; Agocs, Janos; Quest, Jürgen


    Within the framework of the EU project ESWIRP the Particle Image Velocimetry (PIV) using high-speed camera and laser has been used to measure the turbulent flow in the wake of a stalled aircraft wing. The measurements took place on the Common Research Model (CRM) provided by NASA in the pressurized cryogenic European Transonic Wind tunnel (ETW). A specific cryo-PIV system has been used and adapted for using high-speed PIV components under the cryogenic conditions of the wind tunnel faci...

  14. Genetics Home Reference: CHARGE syndrome (United States)

    ... combination of major and minor characteristics. The major characteristics of CHARGE syndrome are common in this disorder and occur less ... and unusually shaped external ears. While the minor characteristics of CHARGE syndrome are common in this disorder, they are also ...

  15. Orchestral Stalls, Honore Daumier (United States)

    Lucero-Criswell, Amber


    Honore Daumier is probably best known as a politically motivated artist. Born in Marseilles in 1808, the French artist lived through one of the most turbulent eras of his country's history. With his artistic prowess and biting wit, he recorded the 1848 revolution, the rise and fall of the Second Empire, the Crimean and Franco-Prussian Wars, and…

  16. Improving Charging-Breeding Simulations with Space-Charge Effects (United States)

    Bilek, Ryan; Kwiatkowski, Ania; Steinbrügge, René


    Rare-isotope-beam facilities use Highly Charged Ions (HCI) for accelerators accelerating heavy ions and to improve measurement precision and resolving power of certain experiments. An Electron Beam Ion Trap (EBIT) is able to create HCI through successive electron impact, charge breeding trapped ions into higher charge states. CBSIM was created to calculate successive charge breeding with an EBIT. It was augmented by transferring it into an object-oriented programming language, including additional elements, improving ion-ion collision factors, and exploring the overlap of the electron beam with the ions. The calculation is enhanced with the effects of residual background gas by computing the space charge due to charge breeding. The program assimilates background species, ionizes and charge breeds them alongside the element being studied, and allows them to interact with the desired species through charge exchange, giving fairer overview of realistic charge breeding. Calculations of charge breeding will be shown for realistic experimental conditions. We reexamined the implementation of ionization energies, cross sections, and ion-ion interactions when charge breeding.

  17. Charge orders in organic charge-transfer salts (United States)

    Kaneko, Ryui; Tocchio, Luca F.; Valentí, Roser; Becca, Federico


    Motivated by recent experimental suggestions of charge-order-driven ferroelectricity in organic charge-transfer salts, such as κ-(BEDT-TTF)2Cu[N(CN)2]Cl, we investigate magnetic and charge-ordered phases that emerge in an extended two-orbital Hubbard model on the anisotropic triangular lattice at 3/4 filling. This model takes into account the presence of two organic BEDT-TTF molecules, which form a dimer on each site of the lattice, and includes short-range intramolecular and intermolecular interactions and hoppings. By using variational wave functions and quantum Monte Carlo techniques, we find two polar states with charge disproportionation inside the dimer, hinting to ferroelectricity. These charge-ordered insulating phases are stabilized in the strongly correlated limit and their actual charge pattern is determined by the relative strength of intradimer to interdimer couplings. Our results suggest that ferroelectricity is not driven by magnetism, since these polar phases can be stabilized also without antiferromagnetic order and provide a possible microscopic explanation of the experimental observations. In addition, a conventional dimer-Mott state (with uniform density and antiferromagnetic order) and a nonpolar charge-ordered state (with charge-rich and charge-poor dimers forming a checkerboard pattern) can be stabilized in the strong-coupling regime. Finally, when electron–electron interactions are weak, metallic states appear, with either uniform charge distribution or a peculiar 12-site periodicity that generates honeycomb-like charge order.

  18. Antiproton charge radius (United States)

    Crivelli, P.; Cooke, D.; Heiss, M. W.


    The upcoming operation of the extra low energy antiprotons ring at CERN, the upgrade of the antiproton decelerator (AD), and the installation in the AD hall of an intense slow positron beam with an expected flux of 1 08 e+ /s will open the possibility for new experiments with antihydrogen (H ¯). Here we propose a scheme to measure the Lamb shift of H ¯. For four months of data taking, we anticipate an uncertainty of 100 ppm. This will provide a test of C P T and the first determination of the antiproton charge radius at the level of 10%.

  19. The Effect of Different Types of Physical Exercise on the Behavioural and Physiological Parameters of Standardbred Horses Housed in Single Stalls

    Directory of Open Access Journals (Sweden)

    Barbara Padalino


    Full Text Available The aim of this study was to investigate the impacts of three different physical exercises on the physiological and behavioural patterns of Standardbred trotters housed in single stalls. Twelve racing mares were observed twice during each different exercise: daily training (DT consisted of forty minutes at slow trot (4-5 m/s in a small track; maximal exercise (ME consisted of 1600 m run at maximal velocity; race (R was a real race of 1600 m. The mares were examined at rest in their stall (Time I, soon after the completion of the exercise (Time II, one hour (Time III, and two hours (Time IV after the exercise. Their heart rate, respiratory rate, and rectal temperature were recorded and they were videotaped in order to complete a focal animal sampling ethogram. All physiological parameters increased after exercise, in accordance with its intensity. After R and ME horses spent more time drinking, eating, and standing. The incidence of abnormal behaviours was very low and it was not affected by the different types of exercise. Overall, the assessment of horse behaviour after physical exercise by means of a focal animal sampling ethogram represents a useful tool to monitor equine welfare.

  20. Avaliação de diferentes materiais para recobrimento de camas em baias de galpão modelo free-stall

    Directory of Open Access Journals (Sweden)

    Daiane Cecchin


    Full Text Available Objetivou-se, com o presente trabalho, comparar o uso de cama de colchão de borracha e de areia no recobrimento da superfície de baias para confinamento tipo free-stall. Foram monitoradas 18 vacas holandesas confinadas em galpão modelo free-stall cujas baias foram recobertas com camas de areia e colchão de borracha (tratamentos. O delineamento experimental foi em blocos casualizados. Os parâmetros comportamentais estudados foram os tempos despendidos nas atividades: deitada em ócio e deitada ruminando, em pé em ócio sobre a cama, em pé ruminando sobre a cama, registrados a cada 10 min. As variáveis ambientais e temperatura da superfície das camas foram registradas a cada hora. Houve maior preferência dos animais pela cama de areia para os comportamentos deitada em ócio e deitada ruminando. As vacas permaneceram mais tempo deitadas em cama de borracha somente nos períodos mais frescos (noite e madrugada, devido à temperatura da cama. A temperatura da borracha foi maior que areia nos horários mais quentes do dia (notadamente durante o período da tarde, enquanto à noite se apresentou mais fria.

  1. Charged Galileon black holes

    International Nuclear Information System (INIS)

    Babichev, Eugeny; Charmousis, Christos; Hassaine, Mokhtar


    We consider an Abelian gauge field coupled to a particular truncation of Horndeski theory. The Galileon field has translation symmetry and couples non minimally both to the metric and the gauge field. When the gauge-scalar coupling is zero the gauge field reduces to a standard Maxwell field. By taking into account the symmetries of the action, we construct charged black hole solutions. Allowing the scalar field to softly break symmetries of spacetime we construct black holes where the scalar field is regular on the black hole event horizon. Some of these solutions can be interpreted as the equivalent of Reissner-Nordstrom black holes of scalar tensor theories with a non trivial scalar field. A self tuning black hole solution found previously is extended to the presence of dyonic charge without affecting whatsoever the self tuning of a large positive cosmological constant. Finally, for a general shift invariant scalar tensor theory we demonstrate that the scalar field Ansatz and method we employ are mathematically compatible with the field equations. This opens up the possibility for novel searches of hairy black holes in a far more general setting of Horndeski theory

  2. Charged boson stars (United States)

    Pugliese, Daniela; Quevedo, Hernando; Rueda H., Jorge A.; Ruffini, Remo


    We study time-independent, spherically symmetric, self-gravitating systems minimally coupled to a scalar field with U(1) gauge symmetry: charged boson stars. We find numerical solutions to the Einstein-Maxwell equations coupled to the relativistic Klein-Gordon equation. It is shown that bound stable configurations exist only for values of the coupling constant less than or equal to a certain critical value. The metric coefficients and the relevant physical quantities, such as the total mass and charge, turn out to be, in general, bound functions of the radial coordinate, reaching their maximum values at a critical value of the scalar field at the origin. We discuss the stability problem from both the quantitative and qualitative point of view. We take into account the electromagnetic contribution to the total mass and investigate the stability issue considering the binding energy per particle. We verify the existence of configurations with positive binding energy in which objects that are apparently bound can be unstable against small perturbations, in full analogy with the effect observed in the mass-radius relation of neutron stars.

  3. Battery charging control methods, electric vehicle charging methods, battery charging apparatuses and rechargeable battery systems (United States)

    Tuffner, Francis K [Richland, WA; Kintner-Meyer, Michael C. W. [Richland, WA; Hammerstrom, Donald J [West Richland, WA; Pratt, Richard M [Richland, WA


    Battery charging control methods, electric vehicle charging methods, battery charging apparatuses and rechargeable battery systems. According to one aspect, a battery charging control method includes accessing information regarding a presence of at least one of a surplus and a deficiency of electrical energy upon an electrical power distribution system at a plurality of different moments in time, and using the information, controlling an adjustment of an amount of the electrical energy provided from the electrical power distribution system to a rechargeable battery to charge the rechargeable battery.

  4. Charge Breeding of Radioactive Ions

    CERN Document Server

    Wenander, F J C


    Charge breeding is a technique to increase the charge state of ions, in many cases radioactive ions. The singly charged radioactive ions, produced in an isotope separator on-line facility, and extracted with a low kinetic energy of some tens of keV, are injected into a charge breeder, where the charge state is increased to Q. The transformed ions are either directed towards a dedicated experiment requiring highly charged ions, or post-accelerated to higher beam energies. In this paper the physics processes involved in the production of highly charged ions will be introduced, and the injection and extraction beam parameters of the charge breeder defined. A description of the three main charge-breeding methods is given, namely: electron stripping in gas jet or foil; external ion injection into an electron-beam ion source/trap (EBIS/T); and external ion injection into an electron cyclotron resonance ion source (ECRIS). In addition, some preparatory devices for charge breeding and practical beam delivery aspects ...

  5. Charge Storage, Conductivity and Charge Profiles of Insulators as Related to Spacecraft Charging (United States)

    Dennison, J. R.; Swaminathan, Prasanna; Frederickson, A. R.


    Dissipation of charges built up near the surface of insulators due to space environment interaction is central to understanding spacecraft charging. Conductivity of insulating materials is key to determine how accumulated charge will distribute across the spacecraft and how rapidly charge imbalance will dissipate. To understand these processes requires knowledge of how charge is deposited within the insulator, the mechanisms for charge trapping and charge transport within the insulator, and how the profile of trapped charge affects the transport and emission of charges from insulators. One must consider generation of mobile electrons and holes, their trapping, thermal de-trapping, mobility and recombination. Conductivity is more appropriately measured for spacecraft charging applications as the "decay" of charge deposited on the surface of an insulator, rather than by flow of current across two electrodes around the sample. We have found that conductivity determined from charge storage decay methods is 102 to 104 smaller than values obtained from classical ASTM and IEC methods for a variety of thin film insulating samples. For typical spacecraft charging conditions, classical conductivity predicts decay times on the order of minutes to hours (less than typical orbit periods); however, the higher charge storage conductivities predict decay times on the order of weeks to months leading to accumulation of charge with subsequent orbits. We found experimental evidence that penetration profiles of radiation and light are exceedingly important, and that internal electric fields due to charge profiles and high-field conduction by trapped electrons must be considered for space applications. We have also studied whether the decay constants depend on incident voltage and flux or on internal charge distributions and electric fields; light-activated discharge of surface charge to distinguish among differing charge trapping centers; and radiation-induced conductivity. Our

  6. Surface charge compensation for a highly charged ion emission microscope

    International Nuclear Information System (INIS)

    McDonald, J.W.; Hamza, A.V.; Newman, M.W.; Holder, J.P.; Schneider, D.H.G.; Schenkel, T.


    A surface charge compensation electron flood gun has been added to the Lawrence Livermore National Laboratory (LLNL) highly charged ion (HCI) emission microscope. HCI surface interaction results in a significant charge residue being left on the surface of insulators and semiconductors. This residual charge causes undesirable aberrations in the microscope images and a reduction of the Time-Of-Flight (TOF) mass resolution when studying the surfaces of insulators and semiconductors. The benefits and problems associated with HCI microscopy and recent results of the electron flood gun enhanced HCI microscope are discussed

  7. Understanding the Linkage between Charging Network Coverage and Charging Opportunity

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Changzheng [ORNL; Lin, Zhenhong [ORNL; Kontou, Eleftheria [University of Florida, Gainesville; Wu, Xing [Lamar University


    Using GPS-based travel survey data, this paper estimates the relationship between public charging network coverage and charging opportunity, defined as the probability of being able to access public charging for a driver at one of his/her stops or at one travel day. Understanding this relationship is of important interests to the electric vehicle industry and government in determining appropriate charging infrastructure deployment level and estimating the impact of public charging on market adoption of electric vehicles. The analysis finds that drivers trip destinations concentrate on a few popular places. If top 1% of most popular places are installed with public chargers, on average, drivers will be able to access public charging at 20% of all their stops and 1/3 of their travel days; If 20% of most popular places are installed with public chargers, drivers will be able to access public charging at 89% of all their stops and 94% of their travel days. These findings are encouraging, implying charging network can be efficiently designed by concentrating at a few popular places while still providing a high level of charging opportunity.

  8. Sequential charged particle reaction

    International Nuclear Information System (INIS)

    Hori, Jun-ichi; Ochiai, Kentaro; Sato, Satoshi; Yamauchi, Michinori; Nishitani, Takeo


    The effective cross sections for producing the sequential reaction products in F82H, pure vanadium and LiF with respect to the 14.9-MeV neutron were obtained and compared with the estimation ones. Since the sequential reactions depend on the secondary charged particles behavior, the effective cross sections are corresponding to the target nuclei and the material composition. The effective cross sections were also estimated by using the EAF-libraries and compared with the experimental ones. There were large discrepancies between estimated and experimental values. Additionally, we showed the contribution of the sequential reaction on the induced activity and dose rate in the boundary region with water. From the present study, it has been clarified that the sequential reactions are of great importance to evaluate the dose rates around the surface of cooling pipe and the activated corrosion products. (author)

  9. 46 CFR 401.430 - Prohibited charges. (United States)


    ... 46 Shipping 8 2010-10-01 2010-10-01 false Prohibited charges. 401.430 Section 401.430 Shipping... Rates, Charges, and Conditions for Pilotage Services § 401.430 Prohibited charges. No rate or charge... the rates and charges set forth in this part, nor shall any rates or charges be made for services...

  10. 12 CFR 226.4 - Finance charge. (United States)


    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Finance charge. 226.4 Section 226.4 Banks and... LENDING (REGULATION Z) General § 226.4 Finance charge. (a) Definition. The finance charge is the cost of...) Charges by third parties. The finance charge includes fees and amounts charged by someone other than the...

  11. Spacelike charges, null-plane charges, and mass splitting

    International Nuclear Information System (INIS)

    Gal-Ezer, E.; Horwitz, L.P.


    The properties of charges defined as integrals over tensor densities and their possible use in the treatment of broken symmetries are studied. It is well known that spacelike integrals over nonconserved densities cannot yield charge operators at a fixed sharp time. However, charge operators which are smeared in time with suitable ''adiabatic'' functions, when there is a mass gap, are well defined; these charges can give rise to a finite algebraic structure only in the infinite-momentum limit, corresponding to an algebra of null-plane charges. For the study of null-plane charges, tensor densities are divided into four classes (very good, good, bad, very bad) according to their transformation properties under the Lorentz group. We argue that in the absence of massless particles members of the first two classes are expected to yield well-defined null-plane charges, while members of the last two classes are not expected to define null-plane charges. The existence of null-plane charges for good densities depends on whether the Pomeron intercept α/sub P/(0) is less than 1 or equal to 1. Null-plane Fourier transforms (which appear in the discussion of current algebra at infinite momentum) are also considered. Null-plane charges may satisfy algebraic relations which involve the Poincare algebra. Owing to domain properties, only semialgebraic relations, which are a generalization of the usual Lie algebraic relations, can be postulated on particle states. By use of these relations, a no-go theorem of the O'Raifeartaigh type, which applies to the null-plane charges, is formulated and proved

  12. Scalable Electric Vehicle Charging Protocols


    Zhang, Liang; Kekatos, Vassilis; Giannakis, Georgios B.


    Although electric vehicles are considered a viable solution to reduce greenhouse gas emissions, their uncoordinated charging could have adverse effects on power system operation. Nevertheless, the task of optimal electric vehicle charging scales unfavorably with the fleet size and the number of control periods, especially when distribution grid limitations are enforced. To this end, vehicle charging is first tackled using the recently revived Frank-Wolfe method. The novel decentralized chargi...

  13. Scientific charge-coupled devices (United States)

    Janesick, James R.; Elliott, Tom; Collins, Stewart; Blouke, Morley M.; Freeman, Jack


    The charge-coupled device dominates an ever-increasing variety of scientific imaging and spectroscopy applications. Recent experience indicates, however, that the full potential of CCD performance lies well beyond that realized in devices currently available.Test data suggest that major improvements are feasible in spectral response, charge collection, charge transfer, and readout noise. These properties, their measurement in existing CCDs, and their potential for future improvement are discussed in this paper.

  14. Fractional Charge Definitions and Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Goldhaber, A.S.


    Fractional charge is known through theoretical and experimental discoveries of isolable objects carrying fractions of familiar charge units--electric charge Q, spin S, and the difference of baryon and lepton numbers B-L. With a few simple assumptions all these effects may be described using a generalized version of charge renormalization for locally conserved charges, in which medium correlations yield familiar adiabatic, continuous renormalization, or sometimes nonadiabatic, discrete renormalization. Fractional charges may be carried by fundamental particles or fundamental solitons. Either picture works for the simplest fractional-quantum-Hall-effect quasiholes, though the particle description is far more general. The only known fundamental solitons in three or fewer space dimensions d are the kink (d = 1), the vortex (d = 2), and the magnetic monopole (d = 3). Further, for a charge not intrinsically coupled to the topological charge of a soliton, only the kink and the monopole may carry fractional values. The same reasoning enforces fractional values of B-L for electrically charged elementary particles.

  15. Low-charge-state linac

    Energy Technology Data Exchange (ETDEWEB)

    Shepard, K.W.; Kim, J.W.


    A design is being developed for a low-charge-state linac suitable for injecting ATLAS with a low-charge-state, radioactive beam. Initial work indicates that the existing ATLAS interdigital superconducting accelerating structures, together with the superconducting quadrupole transverse focussing element discussed above, provides a basis for a high-performance low-charge-state linac. The initial 2 or 3 MV of such a linac could be based on a normally-conducting, low-frequency RFQ, possibly combined with 24-MHz superconducting interdigital structures. Beam dynamics studies of the whole low-charge-state post-accelerator section were carried out in early FY 1995.

  16. Effect of timing of relocation of replacement gilts from group pens to individual stalls before breeding on fertility and well-being. (United States)

    Knox, R V; Shen, J; Greiner, L L; Connor, J F


    Variation in gilt fertility is associated with increased replacement and reduced longevity. Stress before breeding is hypothesized to be involved in reduced fertility. This study tested the timing of gilt relocation from pens to individual stalls before breeding on fertility and well-being. The experiment was performed in replicates on a commercial research farm. After detection of first estrus, gilts ( = 563) were assigned to treatment for relocation into stalls 3 wk (REL3wk), 2 wk (REL2wk), or 1 wk (REL1wk) before breeding at second estrus. Subsets of gilts from each treatment ( = 60) were selected for assessment of follicles at second estrus. Data included interestrus interval, number of services, conception, farrowing, total born, and wean to service interval. Piglet birth weight was obtained on subsets of litters ( = 42/treatment). Measures of well-being included BW, backfat, BCS, lesions, and lameness from wk 1 after first estrus until wk 16. Gilt BW at wk 5 (158.4 kg) was not affected ( > 0.10) by treatment. Measures of BCS, lameness, and lesions at breeding and throughout gestation did not differ ( > 0.10). Treatment did not affect ( > 0.10) gilts expressing a normal interestrus interval of 18 to 24 d (83.4%) but did influence ( Gilts in REL3wk had a shorter ( Gilts with shorter intervals ( = 24) had fewer total born while gilts expressing longer cycles ( = 65) had reduced farrowing rates. The number of services (1.9) and number of follicles (19.7) at breeding were not affected ( > 0.10) by relocation. There was no effect of treatment on farrowing rate (85.2%), born alive (12.6), or any litter birth weight measures ( > 0.10). The percentage of sows bred within 7 d after weaning (94.4%) was also not affected by treatment ( > 0.10). These results suggest that the timing of relocation before breeding had no effect on well-being or on the majority of gilts with normal estrous cycles and their subsequent fertility. However, a smaller proportion of the gilts

  17. Phenotypes of dnaXE145A Mutant Cells Indicate that the Escherichia coli Clamp Loader Has a Role in the Restart of Stalled Replication Forks. (United States)

    Flåtten, Ingvild; Helgesen, Emily; Pedersen, Ida Benedikte; Waldminghaus, Torsten; Rothe, Christiane; Taipale, Riikka; Johnsen, Line; Skarstad, Kirsten


    The Escherichia coli dnaX E145A mutation was discovered in connection with a screen for multicopy suppressors of the temperature-sensitive topoisomerase IV mutation parE10 The gene for the clamp loader subunits τ and γ, dnaX , but not the mutant dnaX E145A , was found to suppress parE10 (Ts) when overexpressed. Purified mutant protein was found to be functional in vitro , and few phenotypes were found in vivo apart from problems with partitioning of DNA in rich medium. We show here that a large number of the replication forks that initiate at oriC never reach the terminus in dnaX E145A mutant cells. The SOS response was found to be induced, and a combination of the dnaX E145A mutation with recBC and recA mutations led to reduced viability. The mutant cells exhibited extensive chromosome fragmentation and degradation upon inactivation of recBC and recA , respectively. The results indicate that the dnaX E145A mutant cells suffer from broken replication forks and that these need to be repaired by homologous recombination. We suggest that the dnaX -encoded τ and γ subunits of the clamp loader, or the clamp loader complex itself, has a role in the restart of stalled replication forks without extensive homologous recombination. IMPORTANCE The E. coli clamp loader complex has a role in coordinating the activity of the replisome at the replication fork and loading β-clamps for lagging-strand synthesis. Replication forks frequently encounter obstacles, such as template lesions, secondary structures, and tightly bound protein complexes, which will lead to fork stalling. Some pathways of fork restart have been characterized, but much is still unknown about the actors and mechanisms involved. We have in this work characterized the dnaX E145A clamp loader mutant. We find that the naturally occurring obstacles encountered by a replication fork are not tackled in a proper way by the mutant clamp loader and suggest a role for the clamp loader in the restart of stalled

  18. Bounds on charged lepton mixing with exotic charged leptons Ф

    Indian Academy of Sciences (India)

    bounds on mixings in charged lepton sector. The threshold of the process. /. × = 2С is high, and masses of light .... between the two sectors (i.e., ordinary weak states ( 0-. OL(R)) to the heavy mass eigenstates (. hL(R)) and exotic ... Ш3 and Й denote third isospin compo- nent and electrical charge of the corresponding fields.

  19. Charge migration and charge transfer in molecular systems

    Directory of Open Access Journals (Sweden)

    Hans Jakob Wörner


    Full Text Available The transfer of charge at the molecular level plays a fundamental role in many areas of chemistry, physics, biology and materials science. Today, more than 60 years after the seminal work of R. A. Marcus, charge transfer is still a very active field of research. An important recent impetus comes from the ability to resolve ever faster temporal events, down to the attosecond time scale. Such a high temporal resolution now offers the possibility to unravel the most elementary quantum dynamics of both electrons and nuclei that participate in the complex process of charge transfer. This review covers recent research that addresses the following questions. Can we reconstruct the migration of charge across a molecule on the atomic length and electronic time scales? Can we use strong laser fields to control charge migration? Can we temporally resolve and understand intramolecular charge transfer in dissociative ionization of small molecules, in transition-metal complexes and in conjugated polymers? Can we tailor molecular systems towards specific charge-transfer processes? What are the time scales of the elementary steps of charge transfer in liquids and nanoparticles? Important new insights into each of these topics, obtained from state-of-the-art ultrafast spectroscopy and/or theoretical methods, are summarized in this review.

  20. Charge Pricing Optimization Model for Private Charging Piles in Beijing

    Directory of Open Access Journals (Sweden)

    Xingping Zhang


    Full Text Available This paper develops a charge pricing model for private charging piles (PCPs by considering the environmental and economic effects of private electric vehicle (PEV charging energy sources and the impact of PCP charging load on the total load. This model simulates users’ responses to different combinations of peak-valley prices based on the charging power of PCPs and user charging transfer rate. According to the regional power structure, it calculates the real-time coal consumption, carbon dioxide emissions reduction, and power generation costs of PEVs on the power generation side. The empirical results demonstrate that the proposed peak-valley time-of-use charging price can not only minimize the peak-valley difference of the total load but also improve the environmental effects of PEVs and the economic income of the power system. The sensitivity analysis shows that the load-shifting effect of PCPs will be more obvious when magnifying the number of PEVs by using the proposed charging price. The case study indicates that the proposed peak, average, and valley price in Beijing should be 1.8, 1, and 0.4 yuan/kWh, which can promote the large-scale adoption of PEVs.

  1. Information Technology and the QS Practice

    Directory of Open Access Journals (Sweden)

    Peter Smith


    Full Text Available The paper examines how Quantity Surveying practices can improve their business performance, market share and profit levels by embracing and evolving with the latest technological developments in electronic business practices and data/information analysis and exchange in the construction industry. Firms in the new millenium will need towork smarterto gain competitive advantage and electronic commerce provides probably the greatest scope for this to be achieved. More importantly, current project procurement trends strongly indicate that firms not able to communicating electronically at all levels with project participants will find it increasingly difficult to secure work. The results of three nationwide surveys of the Australian Quantity Surveying profession spanning from 1995 to 1999 are used to identify current business practices and technology utilisation by Quantity Surveying firms and to analyse whether firms are positioning themselves to meet future industryrequirements. The paper concludes with a range of Information Technology strategies aimed at improving business opportunities and performance for Quantity Surveying firms.

  2. Experimental studies of flow separation and stalling on two-dimensional airfoils at low speeds. Phase 2: Studies with Fowler flap extended (United States)

    Seetharam, H. C.; Wentz, W. H., Jr.


    Results were given on experimental studies of flow separation and stalling on a two-dimensional GA(W)-1 17 percent thick airfoil with an extended Fowler flap. Experimental velocity profiles obtained from a five tube probe survey with optimum flap gap and overlap setting (flap at 40 deg) are shown at various stations above, below, and behind the airfoil/flap combination for various angles of attack. The typical zones of steady flow, intermittent turbulence, and large scale turbulence were obtained from a hot wire anemometer survey and are depicted graphically for an angle of attack of 12.5 deg. Local skin friction distributions were obtained and are given for various angles of attack. Computer plots of the boundary layer profiles are shown for the case of the flap at 40 deg. Static pressure contours are also given. A GA(W)-2 section model was fabricated with 30 percent Fowler flaps and with pressure tabs.

  3. Quantum charged rigid membrane

    International Nuclear Information System (INIS)

    Cordero, Ruben; Molgado, Alberto; Rojas, Efrain


    The early Dirac proposal to model the electron as a charged membrane is reviewed. A rigidity term, instead of the natural membrane tension, involving linearly the extrinsic curvature of the worldvolume swept out by the membrane is considered in the action modeling the bubble in the presence of an electromagnetic field. We set up this model as a genuine second-order derivative theory by considering a non-trivial boundary term which plays a relevant part in our formulation. The Lagrangian in question is linear in the bubble acceleration and by means of the Ostrogradski-Hamiltonian approach, we observed that the theory comprises the management of both first- and second-class constraints. We thus show that our second-order approach is robust allowing for a proper quantization. We found an effective quantum potential which permits us to compute bounded states for the system. We comment on the possibility of describing brane world universes by invoking this kind of second-order correction terms.

  4. Quantum charged rigid membrane

    Energy Technology Data Exchange (ETDEWEB)

    Cordero, Ruben [Departamento de Fisica, Escuela Superior de Fisica y Matematicas del I.P.N., Unidad Adolfo Lopez Mateos, Edificio 9, 07738 Mexico, D.F. (Mexico); Molgado, Alberto [Unidad Academica de Fisica, Universidad Autonoma de Zacatecas, Zacatecas Zac. (Mexico); Rojas, Efrain, E-mail:, E-mail:, E-mail: [Departamento de Fisica, Facultad de Fisica e Inteligencia Artificial, Universidad Veracruzana, 91000 Xalapa, Veracruz (Mexico)


    The early Dirac proposal to model the electron as a charged membrane is reviewed. A rigidity term, instead of the natural membrane tension, involving linearly the extrinsic curvature of the worldvolume swept out by the membrane is considered in the action modeling the bubble in the presence of an electromagnetic field. We set up this model as a genuine second-order derivative theory by considering a non-trivial boundary term which plays a relevant part in our formulation. The Lagrangian in question is linear in the bubble acceleration and by means of the Ostrogradski-Hamiltonian approach, we observed that the theory comprises the management of both first- and second-class constraints. We thus show that our second-order approach is robust allowing for a proper quantization. We found an effective quantum potential which permits us to compute bounded states for the system. We comment on the possibility of describing brane world universes by invoking this kind of second-order correction terms.

  5. Filling of charged cylindrical capillaries

    NARCIS (Netherlands)

    Das, S.; Chanda, Sourayon; Eijkel, Jan C.T.; Tas, Niels Roelof; Chakraborty, Suman; Mitra, Sushanta K.


    We provide an analytical model to describe the filling dynamics of horizontal cylindrical capillaries having charged walls. The presence of surface charge leads to two distinct effects: It leads to a retarding electrical force on the liquid column and also causes a reduced viscous drag force because

  6. Charged-lepton flavour physics

    Indian Academy of Sciences (India)

    Abstract. This write-up on a talk at the 2011 Lepton–Photon symposium in Mumbai, India, summarizes recent results in the charged-lepton flavour sector. Searches for charged-lepton flavour violation, lepton electric dipole moments and flavour-conserving CP violation are reviewed here. Recent progress in -lepton physics ...

  7. Environmental charges in airline markets

    Energy Technology Data Exchange (ETDEWEB)

    Carlsson, Fredrik [Goeteborg Univ., Dept. of Economics, Goeteborg (Sweden)


    Over the last two decades many airline markets have been deregulated, resulting in increased competition and use of different types of networks. At the same time there has been an intense discussion on environmental taxation of airline traffic. It is likely that an optimal environmental charge and the effects of a charge differ between different types of aviation markets. In this paper, we derive optimal flight (environmental) charges for different types of airline markets. The first type of market is a multiproduct monopoly airline operating either a point-to-point network or a hub-and-spoke network. The optimal charge is shown to be similar in construction to an optimal charge for a monopolist. We also compare the environmental impact of the two types of networks. Given no differences in marginal damages between airports we find that an airline will always choose the network with the highest environmental damages. The second type of market we investigate is a multiproduct duopoly, where two airlines compete in both passengers and flights. The formulation of the optimal charge is similar to the optimal charge of a single product oligopoly. However, we also show that it is, because of strategic effects, difficult to determine the effects of the charge on the number of flights. (Author)

  8. The efforts of a multidisciplinary approach in the rehabilitation institute for deaf children: A psychosocial intervention aimed at breaking the pattern of stalled productivity

    Directory of Open Access Journals (Sweden)

    Langher Viviana


    Full Text Available The multidisciplinary approach for the treatment of hearing impaired children presented the work group with several tasks: the group had to integrate different competences and techniques, to share common treatment goals, to manage relational dynamics with the children and their parents, and to explore the families' expectancies. These efforts may create stressful conditions for the work group and, consequently, might negatively affect the quality of the intervention to be carried out. Our aim was to illustrate a psychosocial analysis performed in a religious Institute for hearing impaired children, intended to break the pattern of the Institute's stalled productivity, to avoid inefficient and fragmented treatments, to prevent unelaborated relational dynamics among the staff members and between the staff and the children's families. By means of the Content Analysis of semi-structured interviews administered to staff-members and families we have analyzed the quality of the teamwork, the relational arrangements towards the families and local services (25 interviews with 5 staff members; the family-Institute relationship and the family's representation and satisfaction of the Institute (7 interviews with 13 hearing impaired parents and non-hearing impaired parents. The institute activity seemed to be more characterized by the maintenance of the relationship with the families per se, rather than oriented to productive goals. The non hearing impaired parents seemed to be more satisfied than the hearing-impaired parents, possibly because the former are more prepared to receive the Institute's help. The stalled productivity can only be overcome by the elaboration of those relational/emotional dynamics which prevent staff members and children's parents from focusing on productive goals. The staffmembers' training should be improved in order to develop specific competences, to perform an integrated, multidisciplinary approach in treatments, to negotiate

  9. Static Gas-Charging Plug (United States)

    Indoe, William


    A gas-charging plug can be easily analyzed for random vibration. The design features two steeped O-rings in a radial configuration at two different diameters, with a 0.050-in. (.1.3-mm) diameter through-hole between the two O-rings. In the charging state, the top O-ring is engaged and sealing. The bottom O-ring outer diameter is not squeezed, and allows air to flow by it into the tank. The inner diameter is stretched to plug the gland diameter, and is restrained by the O-ring groove. The charging port bushing provides mechanical stop to restrain the plug during gas charge removal. It also prevents the plug from becoming a projectile when removing gas charge from the accumulator. The plug can easily be verified after installation to ensure leakage requirements are met.

  10. Simulation for signal charge transfer of charge coupled devices

    International Nuclear Information System (INIS)

    Wang Zujun; Liu Yinong; Chen Wei; Tang Benqi; Xiao Zhigang; Huang Shaoyan; Liu Minbo; Zhang Yong


    Physical device models and numerical processing methods are presented to simulate a linear buried channel charge coupled devices (CCDs). The dynamic transfer process of CCD is carried out by a three-phase clock pulse driver. By using the semiconductor device simulation software MEDICI, dynamic transfer pictures of signal charges cells, electron concentration and electrostatic potential are presented. The key parameters of CCD such as charge transfer efficiency (CTE) and dark electrons are numerically simulated. The simulation results agree with the theoretic and experimental results. (semiconductor devices)

  11. Radiation by moving charges

    International Nuclear Information System (INIS)

    Geloni, Gianluca; Kocharyan, Vitali; Saldin, Evgeni


    It is generally accepted that in order to describe the dynamics of relativistic particles in the laboratory (lab) frame it is sufficient to take into account the relativistic dependence of the particle momenta on the velocity. This solution of the dynamics problem in the lab frame makes no reference to Lorentz transformations. For this reason they are not discussed in particle tracking calculations in accelerator and plasma physics. It is generally believed that the electrodynamics problem can be treated within the same ''single inertial frame'' description without reference to Lorentz transformations. In particular, in order to evaluate radiation fields arising from charged particles in motion we need to know their velocities and positions as a function of the lab frame time t. The relativistic motion of a particle in the lab frame is described by Newton's second law ''corrected'' for the relativistic dependence of momentum on velocity. It is assumed in all standard derivations that one can perform identification of the trajectories in the source part of the usual Maxwell's equations with the trajectories vector x(t) measured (or calculated by using the corrected Newton's second law) in the lab frame. This way of coupling fields and particles is considered since more than a century as the relativistically correct procedure.We argue that this procedure needs to be changed, and we demonstrate the following, completely counterintuitive statement: the results of conventional theory of radiation by relativistically moving charges are not consistent with the principle of relativity. In order to find the trajectory of a particle in the lab frame consistent with the usual Maxwell's equations, one needs to solve the dynamic equation inmanifestly covariant form by using the coordinate-independent proper time τ to parameterize the particle world-line in space-time. We show that there is a difference between &apos

  12. Charge-pump voltage converter (United States)

    Brainard, John P [Albuquerque, NM; Christenson, Todd R [Albuquerque, NM


    A charge-pump voltage converter for converting a low voltage provided by a low-voltage source to a higher voltage. Charge is inductively generated on a transfer rotor electrode during its transit past an inductor stator electrode and subsequently transferred by the rotating rotor to a collector stator electrode for storage or use. Repetition of the charge transfer process leads to a build-up of voltage on a charge-receiving device. Connection of multiple charge-pump voltage converters in series can generate higher voltages, and connection of multiple charge-pump voltage converters in parallel can generate higher currents. Microelectromechanical (MEMS) embodiments of this invention provide a small and compact high-voltage (several hundred V) voltage source starting with a few-V initial voltage source. The microscale size of many embodiments of this invention make it ideally suited for MEMS- and other micro-applications where integration of the voltage or charge source in a small package is highly desirable.

  13. Big break for charge symmetry

    CERN Document Server

    Miller, G A


    Two new experiments have detected charge-symmetry breaking, the mechanism responsible for protons and neutrons having different masses. Symmetry is a crucial concept in the theories that describe the subatomic world because it has an intimate connection with the laws of conservation. The theory of the strong interaction between quarks - quantum chromodynamics - is approximately invariant under what is called charge symmetry. In other words, if we swap an up quark for a down quark, then the strong interaction will look almost the same. This symmetry is related to the concept of sup i sospin sup , and is not the same as charge conjugation (in which a particle is replaced by its antiparticle). Charge symmetry is broken by the competition between two different effects. The first is the small difference in mass between up and down quarks, which is about 200 times less than the mass of the proton. The second is their different electric charges. The up quark has a charge of +2/3 in units of the proton charge, while ...

  14. 31 CFR 8.58 - Supplemental charges. (United States)


    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Supplemental charges. 8.58 Section 8... ALCOHOL, TOBACCO AND FIREARMS Disciplinary Proceedings § 8.58 Supplemental charges. If it appears that the... supplemental charges against the respondent. These supplemental charges may be tried with other charges in the...

  15. 7 CFR 1767.23 - Interest charges. (United States)


    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Interest charges. 1767.23 Section 1767.23 Agriculture... charges. The interest charges accounts identified in this section shall be used by all RUS borrowers. Interest Charges 427Interest on Long-Term Debt 427.3Interest Charged to Construction—Credit 428Amortization...

  16. 12 CFR 269b.110 - Charges. (United States)


    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Charges. 269b.110 Section 269b.110 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM CHARGES OF UNFAIR LABOR PRACTICES Charges of Violations of § 269.6 (of the Policy) § 269b.110 Charges. A charge...

  17. 20 CFR 901.38 - Supplemental charges. (United States)


    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Supplemental charges. 901.38 Section 901.38... Enrollment § 901.38 Supplemental charges. If it appears to the Executive Director that the respondent in his... charges against the respondent. Such supplemental charges may be tried with other charges in the case...

  18. 46 CFR 401.431 - Disputed charges. (United States)


    ... 46 Shipping 8 2010-10-01 2010-10-01 false Disputed charges. 401.431 Section 401.431 Shipping COAST..., Charges, and Conditions for Pilotage Services § 401.431 Disputed charges. (a) Any rate or charge applied... charge prohibited by § 401.430, may be appealed to the Director for an advisory opinion as to whether...

  19. Charge density waves in solids

    CERN Document Server

    Gor'kov, LP


    The latest addition to this series covers a field which is commonly referred to as charge density wave dynamics.The most thoroughly investigated materials are inorganic linear chain compounds with highly anisotropic electronic properties. The volume opens with an examination of their structural properties and the essential features which allow charge density waves to develop.The behaviour of the charge density waves, where interesting phenomena are observed, is treated both from a theoretical and an experimental standpoint. The role of impurities in statics and dynamics is considered and an

  20. New spectrometer for charged particles

    International Nuclear Information System (INIS)

    Wajsfelner, Rene


    This thesis is devoted to the study and development of an electrostatic spectrometer which is not only more accurate for the determination of size distributions of electrically charged radio-active atmospheric aerosols, but which can also be used for measuring the grain-size distribution of any cloud of particles which will previously have been charged according to a known, reproducible law. An experimental study has been made of the development of this precipitator and also of its calibration. The electrical charge on spherical polystyrene latex particles suspended in air by atomization has been studied; a theoretical explanation of these results is put forward. (author) [fr

  1. Replacement charging belts - A Review

    Energy Technology Data Exchange (ETDEWEB)

    Bahner, Klaus [AMS 14C Dating Centre, University of Aarhus (Denmark)


    Manufacturing of the original High Voltage Engineering Corp. charging belts has been ceased many years ago, thus leaving users of these accelerators without access to a critical spare part. During the past 6 years we experimented with industrial conveyor belts, supplied by the Forbo Siegling GmbH as replacement charging belts. Our EN accelerator runs routinely on these belts over the past years and performs very well. Furthermore this so called 'Siegling belt' has been adopted by other laboratories, indicating that a viable solution for the charging belt problem in general has been found. This review addresses both the technical aspects of finding a replacement charging belt and our specific experiences with the Siegling belt.

  2. VT Data - Electric Charging Stations (United States)

    Vermont Center for Geographic Information — Locations of Electric Charging Stations provided by the NREL national laboratory of the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy....

  3. Dynamics of charges and solitons (United States)

    Barros, Manuel; Ferrández, Ángel; Garay, Óscar J.


    We first show that trajectories traced by charges moving in rotational magnetic fields are, basically, the non-parallel geodesics of surfaces of revolution with coincident axis. Thus, people living in a surface of revolution are not able to sense the magnetic Hall effect induced by the surrounding magnetic field and perceive charges as influenced, exclusively, by the gravity action on the surface of revolution. Secondly, the extended Hasimoto transformations are introduced and then used to identify trajectories of charges moving through a Killing rotational magnetic field in terms of non-circular elastic curves. As a consequence, we see that in this case charges evolve along trajectories which are obtained as extended Hasimoto transforms of solitons of the filament equation.

  4. ESA's tools for internal charging

    International Nuclear Information System (INIS)

    Soerensen, J.; Rodgers, D.J.; Ryden, K.A.; Latham, P.M.; Wrenn, G.L.; Levy, L.; Panabiere, G.


    Electrostatic discharges, caused by bulk charging of spacecraft insulating materials, are a major cause of satellite anomalies. This is a presentation of ESA's tools to assess whether a given structure is liable to experience electrostatic discharges. (authors)

  5. Measuring momentum for charged particle tomography (United States)

    Morris, Christopher; Fraser, Andrew Mcleod; Schultz, Larry Joe; Borozdin, Konstantin N.; Klimenko, Alexei Vasilievich; Sossong, Michael James; Blanpied, Gary


    Methods, apparatus and systems for detecting charged particles and obtaining tomography of a volume by measuring charged particles including measuring the momentum of a charged particle passing through a charged particle detector. Sets of position sensitive detectors measure scattering of the charged particle. The position sensitive detectors having sufficient mass to cause the charged particle passing through the position sensitive detectors to scatter in the position sensitive detectors. A controller can be adapted and arranged to receive scattering measurements of the charged particle from the charged particle detector, determine at least one trajectory of the charged particle from the measured scattering; and determine at least one momentum measurement of the charged particle from the at least one trajectory. The charged particle can be a cosmic ray-produced charged particle, such as a cosmic ray-produced muon. The position sensitive detectors can be drift cells, such as gas-filled drift tubes.

  6. Charged particle acceleration with plasmas

    International Nuclear Information System (INIS)

    Bravo O, A.


    Under certain conditions it is possible to create spatial charge waves (OCE) in a plasma (ionized gas) through some disturbance mechanism, the phenomenon produces electric fields of high intensity that are propagated at velocities near to a c. When charged particles are connected to such OCE they may be accelerated to very high energies in short distances. At present electric fields of approximately 10 7 V/cm have been observed. (Author). 4 refs

  7. Sodium vapor charge exchange cell

    International Nuclear Information System (INIS)

    Hiddleston, H.R.; Fasolo, J.A.; Minette, D.C.; Chrien, R.E.; Frederick, J.A.


    An operational sequential charge-exchange ion source yielding a 50 MeV H - current of approximately 8 mA is planned for use with the Argonne 500 MeV booster synchrotron. Progress is reported on the development of a sodium vapor charge-exchange cell as part of that planned effort. Design, fabrication, and operating results to date are presented and discussed

  8. Sodium vapor charge exchange cell

    International Nuclear Information System (INIS)

    Hiddleston, H.R.; Fasolo, J.A.; Minette, D.C.; Chrien, R.E.; Frederick, J.A.


    An operational sequential charge-exchange ion source yielding a 50 MeV H - current of approximately 8 mA is planned for use with the Argonne 500 MeV booster synchrotron. We report on the progress for development of a sodium vapor charge-exchange cell as part of that planned effort. Design, fabrication, and operating results to date are presented and discussed. (author)

  9. Fractional Effective Charges and Misner-Wheeler Charge without Charge Effect in Metamaterials

    Directory of Open Access Journals (Sweden)

    Igor Smolyaninov


    Full Text Available Transformation optics enables engineering of the effective topology and dimensionality of the optical space in metamaterials. Nonlinear optics of such metamaterials may mimic Kaluza-Klein theories having one or more kinds of effective charges. As a result, novel photon blockade devices may be realized. Here we demonstrate that an electromagnetic wormhole may be designed, which connects two points of such an optical space and changes its effective topological connectivity. Electromagnetic field configurations, which exhibit fractional effective charges, appear as a result of such topology change. Moreover, such effects as Misner-Wheeler “charge without charge” may be replicated.

  10. A Novel Methodology for Charging Station Deployment (United States)

    Sun, Zhonghao; Zhao, Yunwei; He, Yueying; Li, Mingzhe


    Lack of charging stations has been a main obstacle to the promotion of electric vehicles. This paper studies deploying charging stations in traffic networks considering grid constraints to balance the charging demand and grid stability. First, we propose a statistical model for charging demand. Then we combine the charging demand model with power grid constraints and give the formulation of the charging station deployment problem. Finally, we propose a theoretical solution for the problem by transforming it to a Markov Decision Process.

  11. Cosmology of a charged universe

    International Nuclear Information System (INIS)

    Barnes, A.


    The Proca generalization of electrodynamics admits the possibility that the universe could possess a net electric charge uniformly distributed throughout space, while possessing no electric field. A charged intergalactic (and intragalactic) medium of this kind could contain enough energy to be of cosmological importance. A general-relativistic model of cosmological expansion dominated by such a charged background has been calculated, and is consistent with present observational limits on the Hubble constant, the decleration parameter, and the age of the universe. However, if this cosmology applied at the present epoch, the very early expansion of the universe would have been much more rapid than in conventional ''big bang'' cosmologies, too rapid for cosmological nucleosynthesis or thermalization of the background radiation to have occurred. Hence, domination of the present expansion by background charge appears to be incompatible with the 3 K background and big-bang production of light elements. If the present background charge density were sufficiently small (but not strictly zero), expansion from the epoch of nucleosynthesis would proceed according to the conventional scenario, but the energy due to the background charge would have dominated at some earlier epoch. This last possibility leads to equality of pressure and energy density in the primordial universe, a condition of special significance in certain cosmological theories

  12. Enabling fast charging - Vehicle considerations (United States)

    Meintz, Andrew; Zhang, Jiucai; Vijayagopal, Ram; Kreutzer, Cory; Ahmed, Shabbir; Bloom, Ira; Burnham, Andrew; Carlson, Richard B.; Dias, Fernando; Dufek, Eric J.; Francfort, James; Hardy, Keith; Jansen, Andrew N.; Keyser, Matthew; Markel, Anthony; Michelbacher, Christopher; Mohanpurkar, Manish; Pesaran, Ahmad; Scoffield, Don; Shirk, Matthew; Stephens, Thomas; Tanim, Tanvir


    To achieve a successful increase in the plug-in battery electric vehicle (BEV) market, it is anticipated that a significant improvement in battery performance is required to increase the range that BEVs can travel and the rate at which they can be recharged. While the range that BEVs can travel on a single recharge is improving, the recharge rate is still much slower than the refueling rate of conventional internal combustion engine vehicles. To achieve comparable recharge times, we explore the vehicle considerations of charge rates of at least 400 kW. Faster recharge is expected to significantly mitigate the perceived deficiencies for long-distance transportation, to provide alternative charging in densely populated areas where overnight charging at home may not be possible, and to reduce range anxiety for travel within a city when unplanned charging may be required. This substantial increase in charging rate is expected to create technical issues in the design of the battery system and the vehicle's electrical architecture that must be resolved. This work focuses on vehicle system design and total recharge time to meet the goals of implementing improved charge rates and the impacts of these expected increases on system voltage and vehicle components.

  13. Charge-exchange collisions of multiply charged ions with atoms

    International Nuclear Information System (INIS)

    Grozdanov, T.P.; Janev, R.K.


    The problem of electron transfer between neutral atoms and multiply charged ions is considered at low and medium energies. It is assumed that a large number of final states are available for the electron transition so that the electron-capture process is treated as a tunnel effect caused by the strong attractive Coulomb field of the multicharged ions. The electron transition probability is obtained in a closed form using the modified-comparison-equation method to solve the Schroedinger equation. An approximately linear dependence of the one-electron transfer cross section on the charge of multicharged ion is found. Cross-section calculations of a number of charge-exchange reactions are performed

  14. Tokamak rotation and charge exchange

    International Nuclear Information System (INIS)

    Hazeltine, R.D.; Rowan, W.L.; Solano, E.R.; Valanju, P.M.


    In the absence of momentum input, tokamak toroidal rotation rates are typically small - no larger in particular than poloidal rotation - even when the radial electric field is strong, as near the plasma edge. This circumstance, contradicting conventional neoclassical theory, is commonly attributed to the rotation damping effect of charge exchange, although a detailed comparison between charge-exchange damping theory and experiment is apparently unavailable. Such a comparison is attempted here in the context of recent TEXT experiments, which compare rotation rates, both poloidal and toroidal, in helium and hydrogen discharges. The helium discharges provide useful data because they are nearly free of ion-neutral charge exchange; they have been found to rotate toroidally in reasonable agreement with neoclassical predictions. The hydrogen experiments show much smaller toroidal motion as usual. The theoretical calculation uses the full charge-exchange operator and assumes plateau collisionality, roughly consistent with the experimental conditions. The authors calculate the ion flow as a function of v cx /v c , where v cx is the charge exchange rate and v c the Coulomb collision frequency. The results are in reasonable accord with the observations. 1 ref

  15. 25 CFR 143.4 - Charges. (United States)


    ... 25 Indians 1 2010-04-01 2010-04-01 false Charges. 143.4 Section 143.4 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES CHARGES FOR GOODS AND SERVICES PROVIDED TO NON-FEDERAL USERS § 143.4 Charges. (a) Charges shall be established by the Assistant Secretary and shall be...

  16. 48 CFR 52.247-17 - Charges. (United States)


    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Charges. 52.247-17 Section... Charges. As prescribed in 47.207-6(a)(2), insert the following clause in solicitations and contracts for transportation or for transportation-related services: Charges (APR 1984) In no event shall charges under this...

  17. 38 CFR 21.7076 - Entitlement charges. (United States)


    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Entitlement charges. 21... Bill-Active Duty) Entitlement § 21.7076 Entitlement charges. (a) Overview. VA will make charges against entitlement as stated in this section. (1) Charges will be made against the entitlement the veteran or...

  18. 14 CFR 1215.113 - User charges. (United States)


    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false User charges. 1215.113 Section 1215.113... (TDRSS) Use and Reimbursement Policy for Non-U.S. Government Users § 1215.113 User charges. (a) The user shall reimburse NASA the sum of the charges for standard and mission-unique services. Charges will be...

  19. 15 CFR 2004.10 - Other charges. (United States)


    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Other charges. 2004.10 Section 2004.10... TRADE REPRESENTATIVE FREEDOM OF INFORMATION POLICIES AND PROCEDURES Costs § 2004.10 Other charges. USTR may apply other charges, including the following: (a) Special charges. USTR shall recover the full...

  20. 50 CFR 600.1015 - Late charges. (United States)


    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Late charges. 600.1015 Section 600.1015... charges. The late charge to fish buyers for fee payment, collection, deposit, and/or disbursement shall be..., deposited, and/or disbursed. The full late charge shall apply to the fee for each month or portion of a...

  1. 75 FR 7411 - Schedule of Water Charges (United States)


    ... DELAWARE RIVER BASIN COMMISSION 18 CFR Part 410 Schedule of Water Charges AGENCY: Delaware River... Administrative Manual--Part III--Basin Regulations--Water Supply Charges to revise the schedule of water charges... commenter and the subject line ``Schedule of Water Charges.'' FOR FURTHER INFORMATION, CONTACT: Please...

  2. Nonlinear screening of charge impurities in graphene


    Katsnelson, M. I.


    It is shown that a ``vacuum polarization'' induced by Coulomb potential in graphene leads to a strong suppression of electric charges even for undoped case (no charge carriers). A standard linear response theory is therefore not applicable to describe the screening of charge impurities in graphene. In particular, it overestimates essentially the contributions of charge impurities into the resistivity of graphene.

  3. On the forces acting on radiating charge

    International Nuclear Information System (INIS)

    Khachatrian, B.V.


    It is shown that the force acting on a radiating charge is stipulated by two reasons- owing to exchange of a momentum between the radiating charge and electromagnetic field of radiation, and also between the charge and field accompanying the charge. 7 refs

  4. 10 CFR 904.7 - Base charge. (United States)


    ... 10 Energy 4 2010-01-01 2010-01-01 false Base charge. 904.7 Section 904.7 Energy DEPARTMENT OF... Marketing § 904.7 Base charge. (a) The Base Charge shall be developed by the Administrator and promulgated in accordance with appropriate DOE regulations. The Base Charge shall be composed of a capacity...

  5. Charged Higgs Analysis in CMS

    CERN Document Server

    Eysermans, Jan


    In this talk an overview is given of the possible searches of the Charged Higgs Boson during run 2 of the LHC data taking period. The Charged Higgs boson emerges in several (minimal) Standard Model (SM) extensions such as the 2 Doublet Higgs Model, which predicts 5 physical Higgs bosons, consistent with the SM Higgs boson. Based on the main production and decay modes, the possible intermediate and final state particles are predicted for a Charged Higgs mass higher than the top quark mass ($m_{H^{\\pm}} > m_t$). In particular, the dominant H to tau nu and H to tb channels are discussed in more detail together with their associated background.

  6. Alternator control for battery charging (United States)

    Brunstetter, Craig A.; Jaye, John R.; Tallarek, Glen E.; Adams, Joseph B.


    In accordance with an aspect of the present disclosure, an electrical system for an automotive vehicle has an electrical generating machine and a battery. A set point voltage, which sets an output voltage of the electrical generating machine, is set by an electronic control unit (ECU). The ECU selects one of a plurality of control modes for controlling the alternator based on an operating state of the vehicle as determined from vehicle operating parameters. The ECU selects a range for the set point voltage based on the selected control mode and then sets the set point voltage within the range based on feedback parameters for that control mode. In an aspect, the control modes include a trickle charge mode and battery charge current is the feedback parameter and the ECU controls the set point voltage within the range to maintain a predetermined battery charge current.

  7. Charge Transport in Electrostatic Radiography. (United States)

    Fallone, B. Gino

    A new analytical hyperbolic expression is presented to describe the full saturation curve of parallel-plate ionization chambers filled with air or with high atomic number gases at elevated pressures. It is shown that all parameters of the saturation curve expression can be calculated from one single measurement of ionization current at a given electric field and air gap thickness. Isothermal charge deposition on polymers to form stable foil electrets by using an apparatus resembling parallel-plate ionization chambers is reported. Charge carriers produced by irradiation of the sensitive air volume drift in the externally applied electric field and get trapped on the polymer surface to form electrets. The time dependence of the polarization and depolarization current densities, the effective electric field in the electret chamber, and the electret surface charge densities are presented for the radiation-induced foil electret and an excellent agreement is obtained with the measured electret data. The theory of linear systems is used to derive the electric field and potential in distance space in the electret chamber. The charging characteristics of ionographi latent images are discussed in terms of saturation characteristics of ionographic chambers. The minimum applied electric field needed for an optimized charge collection in the ionographic chamber is presented in terms of both the electret characteristic polarization time and the electret relaxation time. The feasibility of radiographic image subtraction based on electrostatic imaging techniques is demonstrated. Latent image charging at one polarity corresponding to the production of the primary image, and latent image discharging with the opposite chamber polarity, are used to create the final image representing the region of interest.

  8. Charge densities and charge noise in mesoscopic conductors

    Indian Academy of Sciences (India)

    We introduce a hierarchy of density of states to characterize the charge distribution in a mesoscopic conductor. At the bottom of this hierarchy are the partial density of states which represent the contribution to the local density of states if both the incident and the out-going scattering channel is prescribed. The partial density ...

  9. Bounds on charged lepton mixing with exotic charged leptons Ф

    Indian Academy of Sciences (India)

    A comprehensive analysis of the mixing between ordinary fermions with canon- ... EL. 0-. R = 0-. OR. 0-. ER. (2) in which subscripts 'O' and 'E' stand for ordinary and exotic leptons respectively. Here we classify all charged leptons as either ordinary or exotic according to their ... EL is a column vector of СL exotic fields.

  10. Charged particle mobility refrigerant analyzer (United States)

    Allman, S.L.; Chunghsuan Chen; Chen, F.C.


    A method for analyzing a gaseous electronegative species comprises the steps of providing an analysis chamber; providing an electric field of known potential within the analysis chamber; admitting into the analysis chamber a gaseous sample containing the gaseous electronegative species; providing a pulse of free electrons within the electric field so that the pulse of free electrons interacts with the gaseous electronegative species so that a swarm of electrically charged particles is produced within the electric field; and, measuring the mobility of the electrically charged particles within the electric field.

  11. Price Based Electric Vehicle Charging

    DEFF Research Database (Denmark)

    Mahat, Pukar; Handl, Martin; Kanstrup, Kenneth


    It is expected that a lot of the new light vehicles in the future will be electrical vehicles (EV). The storage capacity of these EVs has the potential to complement renewable energy resources and mitigate its intermittency. However, EV charging may have negative impact on the power grid. This pa......It is expected that a lot of the new light vehicles in the future will be electrical vehicles (EV). The storage capacity of these EVs has the potential to complement renewable energy resources and mitigate its intermittency. However, EV charging may have negative impact on the power grid...

  12. q-deformed charged fermion coherent states and SU(3) charged, Hyper-charged fermion coherent states

    International Nuclear Information System (INIS)

    Hao Sanru; Li Guanghua; Long Junyan


    By virtue of the algebra of the q-deformed fermion oscillators, the q-deformed charged fermion coherent states and SU(3) charged, hyper-charged fermion coherent states are discussed. The explicit forms of the two kinds of coherent states mentioned above are obtained by making use of the completeness of base vectors in the q-fermion Fock space. By comparing the q-deformed results with the ordinary results, it is found that the q-deformed charged fermion coherent states and SU(3) charged, hyper-charged fermion coherent states are automatically reduced to the ordinary charged fermion coherent states and SU(3) charged hyper-charged fermion coherent states if the deformed parameter q→1

  13. 20 CFR 655.173 - Setting meal charges; petition for higher meal charges. (United States)


    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Setting meal charges; petition for higher meal charges. 655.173 Section 655.173 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION... Setting meal charges; petition for higher meal charges. (a) Meal charges. Until a new amount is set under...

  14. A charged spherically symmetric solution

    Indian Academy of Sciences (India)

    By setting the charge contribution to zero we regain an (uncharged) perfect fluid solution found previously with the equation of state =+ constant, which is a generalisation of a stiff equation of state. Our class of ... Govinder1. School of Mathematical and Statistical Sciences, University of Natal, Durban 4041, South Africa ...

  15. Sounding the Charge for Change (United States)

    Haycock, Brooke


    Lessons emerging now from successful schools have much to teach us about the practices of dynamic leaders. But if leaders can't talk about the what and the why of those practices in ways that inspire their staffs to action, they may change programs or policies, but they'll never change people. There are hard-charging school and district leaders…

  16. H- charge exchange injection systems

    International Nuclear Information System (INIS)

    Ankenbrandt, C.; Curtis, C.; Hojvat, C.; Johnson, R.P.; Owen, C.; Schmidt, C.; Teng, L.; Webber, R.C.


    The techniques and components required for injection of protons into cyclic accelerators by means of H - charge exchange processes are reviewed, with emphasis on the experience at Fermilab. The advantages of the technique are described. The design and performance of the system of injection of H - ions into the Fermilab Booster are detailed. (Auth.)

  17. A charged spherically symmetric solution

    Indian Academy of Sciences (India)

    A charged spherically symmetric solution. K MOODLEY, S D MAHARAJ and K S GOVINDER. School of Mathematical and Statistical Sciences, University of Natal, Durban 4041, South Africa. Email: MS received 8 April 2002; revised 7 April 2003; accepted 23 June 2003. Abstract. We find a solution of the ...

  18. Charging transient in polyvinyl formal

    Indian Academy of Sciences (India)


    401–406. © Indian Academy of Sciences. 401. Charging transient in polyvinyl formal. P K KHARE*, P L JAIN† and R K PANDEY‡. Department of Postgraduate Studies & Research in Physics & Electronics, Rani Durgavati University,. Jabalpur 482 001, India. †Department of Physics, Government PG College, Damoh 470 ...

  19. Floating liquid bridge charge dynamics (United States)

    Teschke, Omar; Soares, David Mendez; Gomes, Whyllerson Evaristo; Valente Filho, Juracyr Ferraz


    The interaction of liquid with electric fields is investigated in a configuration where up to 13 kV are applied between electrodes resulting in a 106 V/m electric field in the capillaries and where there is the formation of a free-standing fluid bridge in the interelectrode gap. The Mott-Gurney equation was fitted to the measured ionization current vs applied voltage curve which indicates that the ionization rate at the high-voltage anode electrode dimethylsulfoxide (DMSO) interface and space charging in the interelectrode gap determine the floating liquid bridge current for a given cathode-to-anode voltage. Space charge effects were measured in the cathode becker and also at the liquid bridge since the ionized charges at the anode migrate to the bridge outer surface and decrease the interfacial tension from 43 mJ/m2 to 29 mJ/m2. Two distinct structural regions then form the bridge, a charged plastic (bulk modulus ˜100 MPa) conducting outer layer with a surface conductivity of ˜10-9 Ω-1, which shapes and supports the floating fluid structure, and an inner liquid cylinder, where DMSO molecules flow.

  20. Charged-lepton flavour physics

    Indian Academy of Sciences (India)


    Nov 10, 2012 ... distribution of charge and EDM in the atom or molecule. Schiff violation is stronger for heavy atoms (growing as Z3) and even stronger for polarizable molecules. It leads to an enhancement of the applied electric field, with factors of roughly −585 for the spherical thallium and 1.4 million for the dipolar YbF.

  1. Smart charging in the Netherlands

    NARCIS (Netherlands)

    Tamis, M.; van den Hoed, R.; Thorsdottir, H.


    As the Dutch electric vehicle (EV) fleet continues to expand, so will the amount of charging sessions increase. This expanding demand for energy will add on to the already existing strain on the grid, primarily during peak hours on workdays in the early morning and evening. This growing energy

  2. Charging transient in polyvinyl formal

    Indian Academy of Sciences (India)


    tally influences all the transport phenomena and their effects at the electrodes. The different facts, including the weak polar structure of polymer, the power-law dependence of current on field, the observed value of 'n' and the thermal activation of current over a certain temperature range indicate that a space charge due to ...

  3. Road usage charge economic analysis. (United States)


    The overall objective of this research is to provide ODOT with up to date information on the economic : impact of various Road User Charge (RUC) alternatives on the stakeholders in the state of Oregon. Of particular : concern to policymakers were the...

  4. Modern charge-density analysis

    CERN Document Server

    Gatti, Carlo


    Focusing on developments from the past 10-15 years, this volume presents an objective overview of the research in charge density analysis. The most promising methodologies are included, in addition to powerful interpretative tools and a survey of important areas of research.

  5. Take Charge of Your Career (United States)

    Brown, Marshall A.


    Today's work world is full of uncertainty. Every day, people hear about another organization going out of business, downsizing, or rightsizing. To prepare for these uncertain times, one must take charge of their own career. This article presents some tips for surviving in today's world of work: (1) Be self-managing; (2) Know what you…

  6. Charge exchange in galaxy clusters (United States)

    Gu, Liyi; Mao, Junjie; de Plaa, Jelle; Raassen, A. J. J.; Shah, Chintan; Kaastra, Jelle S.


    Context. Though theoretically expected, the charge exchange emission from galaxy clusters has never been confidently detected. Accumulating hints were reported recently, including a rather marginal detection with the Hitomi data of the Perseus cluster. As previously suggested, a detection of charge exchange line emission from galaxy clusters would not only impact the interpretation of the newly discovered 3.5 keV line, but also open up a new research topic on the interaction between hot and cold matter in clusters. Aim. We aim to perform the most systematic search for the O VIII charge exchange line in cluster spectra using the RGS on board XMM-Newton. Methods: We introduce a sample of 21 clusters observed with the RGS. In order to search for O VIII charge exchange, the sample selection criterion is a >35σ detection of the O VIII Lyα line in the archival RGS spectra. The dominating thermal plasma emission is modeled and subtracted with a two-temperature thermal component, and the residuals are stacked for the line search. The systematic uncertainties in the fits are quantified by refitting the spectra with a varying continuum and line broadening. Results: By the residual stacking, we do find a hint of a line-like feature at 14.82 Å, the characteristic wavelength expected for oxygen charge exchange. This feature has a marginal significance of 2.8σ, and the average equivalent width is 2.5 × 10-4 keV. We further demonstrate that the putative feature can be barely affected by the systematic errors from continuum modeling and instrumental effects, or the atomic uncertainties of the neighboring thermal lines. Conclusions: Assuming a realistic temperature and abundance pattern, the physical model implied by the possible oxygen line agrees well with the theoretical model proposed previously to explain the reported 3.5 keV line. If the charge exchange source indeed exists, we expect that the oxygen abundance could have been overestimated by 8-22% in previous X

  7. Complexation behavior of oppositely charged polyelectrolytes: Effect of charge distribution

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Mingtian; Li, Baohui, E-mail:, E-mail: [School of Physics and Key Laboratory of Functional Polymer Materials of Ministry of Education, Nankai University, Tianjin 300071 (China); Zhou, Jihan; Su, Cuicui; Niu, Lin; Liang, Dehai, E-mail:, E-mail: [Beijing National Laboratory for Molecular Sciences and the Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871 (China)


    Complexation behavior of oppositely charged polyelectrolytes in a solution is investigated using a combination of computer simulations and experiments, focusing on the influence of polyelectrolyte charge distributions along the chains on the structure of the polyelectrolyte complexes. The simulations are performed using Monte Carlo with the replica-exchange algorithm for three model systems where each system is composed of a mixture of two types of oppositely charged model polyelectrolyte chains (EGEG){sub 5}/(KGKG){sub 5}, (EEGG){sub 5}/(KKGG){sub 5}, and (EEGG){sub 5}/(KGKG){sub 5}, in a solution including explicit solvent molecules. Among the three model systems, only the charge distributions along the chains are not identical. Thermodynamic quantities are calculated as a function of temperature (or ionic strength), and the microscopic structures of complexes are examined. It is found that the three systems have different transition temperatures, and form complexes with different sizes, structures, and densities at a given temperature. Complex microscopic structures with an alternating arrangement of one monolayer of E/K monomers and one monolayer of G monomers, with one bilayer of E and K monomers and one bilayer of G monomers, and with a mixture of monolayer and bilayer of E/K monomers in a box shape and a trilayer of G monomers inside the box are obtained for the three mixture systems, respectively. The experiments are carried out for three systems where each is composed of a mixture of two types of oppositely charged peptide chains. Each peptide chain is composed of Lysine (K) and glycine (G) or glutamate (E) and G, in solution, and the chain length and amino acid sequences, and hence the charge distribution, are precisely controlled, and all of them are identical with those for the corresponding model chain. The complexation behavior and complex structures are characterized through laser light scattering and atomic force microscopy measurements. The order

  8. An Improved Wireless Battery Charging System

    Directory of Open Access Journals (Sweden)

    Woo-Seok Lee


    Full Text Available This paper presents a direct wireless battery charging system. The output current of the series-series compensated wireless power transfer (SS-WPT system is used as a current source, and the output voltage of AC-DC converter controls the current source. Therefore, the proposed wireless battery charging system needs no battery charging circuit to carry out charging profiles, and can solve space constraints and thermal problems in many battery applications. In addition, the proposed wireless battery charging system can implement easily most other charging profiles. In this paper, the proposed wireless battery charging system is implemented and the feasibility is verified experimentally according to constant-current constant-voltage charging profile or multi-step current charging profile.

  9. Charge imbalance: its relaxation, diffusion and oscillation

    International Nuclear Information System (INIS)

    Pethick, C.J.


    In this article, the authors use a model for charge density based on two charge components: the normal quasiparticle component and the superfluid/condensate component. Based on the quasiparticle Boltzmann equation, this two-component model, when used in nonequilibrium contexts, is fruitful in describing a variety of charge-imbalance phenomena in superconductors. The authors discuss various methods of generating charge-imbalances, charge-imbalance relaxation processes (such as phonons, impurity scattering and magnetic impurities) and applications of the two-component model of charge imbalance to spatially inhomogeneous conditions

  10. Detection of elementary charges on colloidal particles. (United States)

    Strubbe, Filip; Beunis, Filip; Neyts, Kristiaan


    We have succeeded in determining the charge of individual colloidal particles with resolution higher than the elementary charge. The number of elementary charges on a particle is obtained from the analysis of optical tracking data of weakly charged silica spheres in an electric field in a nonpolar medium. The analysis also yields an accurate value of the particle size. Measurement of the charge as a function of time reveals events in which the particle loses or gains an elementary charge due to ionization or recombination processes at the surface.

  11. Stability of charged strange quark stars

    Energy Technology Data Exchange (ETDEWEB)

    Arbañil, José D. V.; Malheiro, Manuel [Departamento de Física, Instituto Tecnológico de Aeronáutica, Centro Técnico Aeroespacial, 12228-900 São José dos Campos, SP (Brazil)


    We investigate the hydrostatic equilibrium and the stability of charged stars made of a charged perfect fluid. The matter contained in the star follows the MIT bag model equation of state and the charge distribution to a power-law of the radial coordinate. The hydrostatic equilibrium and the stability of charged strange stars are analyzed using the Tolman-Oppenheimer-Volkoff equation and the Chandrasekhar’s equation pulsation, respectively. These two equation are modified from their original form to the inclusion of the electric charge. We found that the stability of the star decreases with the increment of the central energy density and with the increment of the amount of charge.

  12. Charge symmetry at the partonic level

    Energy Technology Data Exchange (ETDEWEB)

    Londergan, J. T.; Peng, J. C.; Thomas, A. W.


    This review article discusses the experimental and theoretical status of partonic charge symmetry. It is shown how the partonic content of various structure functions gets redefined when the assumption of charge symmetry is relaxed. We review various theoretical and phenomenological models for charge symmetry violation in parton distribution functions. We summarize the current experimental upper limits on charge symmetry violation in parton distributions. A series of experiments are presented, which might reveal partonic charge symmetry violation, or alternatively might lower the current upper limits on parton charge symmetry violation.

  13. charge

    African Journals Online (AJOL)

    PROFESSOR ADEOYE ADENIYI MD; FMC (PAED) F WACP. Distinguished Fellow of the Postgraduate Medical College of Nigeria. COURTESIES. The book of Apocrypha which is incorporated in some editions of the Holy Bible, there is a great eulogy in Ecclessiasticus 44:'°'15 it is appropriate for this occasion and I read —.

  14. Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage. (United States)

    Waraky, Ahmed; Lin, Yingbo; Warsito, Dudi; Haglund, Felix; Aleem, Eiman; Larsson, Olle


    We have previously shown that the insulin-like growth factor 1 receptor (IGF-1R) translocates to the cell nucleus, where it binds to enhancer-like regions and increases gene transcription. Further studies have demonstrated that nuclear IGF-1R (nIGF-1R) physically and functionally interacts with some nuclear proteins, i.e. the lymphoid enhancer-binding factor 1 (Lef1), histone H3, and Brahma-related gene-1 proteins. In this study, we identified the proliferating cell nuclear antigen (PCNA) as a nIGF-1R-binding partner. PCNA is a pivotal component of the replication fork machinery and a main regulator of the DNA damage tolerance (DDT) pathway. We found that IGF-1R interacts with and phosphorylates PCNA in human embryonic stem cells and other cell lines. In vitro MS analysis of PCNA co-incubated with the IGF-1R kinase indicated tyrosine residues 60, 133, and 250 in PCNA as IGF-1R targets, and PCNA phosphorylation was followed by mono- and polyubiquitination. Co-immunoprecipitation experiments suggested that these ubiquitination events may be mediated by DDT-dependent E2/E3 ligases ( e.g. RAD18 and SHPRH/HLTF). Absence of IGF-1R or mutation of Tyr-60, Tyr-133, or Tyr-250 in PCNA abrogated its ubiquitination. Unlike in cells expressing IGF-1R, externally induced DNA damage in IGF-1R-negative cells caused G 1 cell cycle arrest and S phase fork stalling. Taken together, our results suggest a role of IGF-1R in DDT. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  15. Study of the stall delay phenomenon and of wind turbine blade dynamics using numerical approaches and NREL's wind tunnel tests

    Energy Technology Data Exchange (ETDEWEB)

    Breton, Simon-Philippe


    The production of electricity from wind has experienced an enormous growth worldwide in the last 20 years. It is now widely seen as a serious alternative to more conventional energy production methods. Improvements are however still possible to make it more cost-effective. This can be done through a better understanding of the fundamental phenomena involved in the interaction of the wind with the wind turbine rotor. This growth in the production of energy from wind is expected to continue at a similar rate in the years to come, helped by the installation of wind turbines at sea, that is becoming a hot topic in the wind energy field today. The phenomenon of stall delay affecting rotating wind turbine blades is an example of an aerodynamic phenomenon that is not yet fully understood. Several models exist to correct for this effect. Five such models were first tested within a vortex wake simulation code based on the modelling of a prescribed wake behind the rotor of the turbine. Comparison was made with wind tunnel test data acquired in head-on flow on a two-bladed 10.1 diameter wind turbine at the National Renewable Energy Laboratories (NREL) in 2000. It revealed a general overprediction of the stall delay effects, at the same time as great disparity was obtained between the different models. Conclusions from this work served as a starting point for a much more thorough investigation on this subject, where several models were tested in terms of different quantities using the same simulation code, and where the application of some of the models was improved. Overprediction of the loads was once again obtained when comparison was made to the NREL results in head-on flow, and none of the models was found to correctly represent the flow physics involved. The premises on which each of the models relies were discussed as a means of better understanding and modelling this phenomenon. The important issue of tip loss was also covered, and guidelines were suggested to improve

  16. Geometrical charged-particle optics

    CERN Document Server

    Rose, Harald


    This second edition is an extended version of the first edition of Geometrical Charged-Particle Optics. The updated reference monograph is intended as a guide for researchers and graduate students who are seeking a comprehensive treatment of the design of instruments and beam-guiding systems of charged particles and their propagation in electromagnetic fields. Wave aspects are included in this edition for explaining electron holography, the Aharanov-Bohm effect and the resolution of electron microscopes limited by diffraction. Several methods for calculating the electromagnetic field are presented and procedures are outlined for calculating the properties of systems with arbitrarily curved axis. Detailed methods are presented for designing and optimizing special components such as aberration correctors, spectrometers, energy filters monochromators, ion traps, electron mirrors and cathode lenses. In particular, the optics of rotationally symmetric lenses, quadrupoles, and systems composed of these elements are...

  17. Geometrical charged-particle optics

    CERN Document Server

    Rose, Harald H


    This reference monograph covers all theoretical aspects of modern geometrical charged-particle optics. It is intended as a guide for researchers, who are involved in the design of electron optical instruments and beam-guiding systems for charged particles, and as a tutorial for graduate students seeking a comprehensive treatment. Procedures for calculating the properties of systems with arbitrarily curved axes are outlined in detail and methods are discussed for designing and optimizing special components such as aberration correctors, spectrometers, energy filters, monochromators, ion traps, electron mirrors and cathode lenses. Also addressed is the design of novel electron optical components enabling sub-Angstroem spatial resolution and sub-0.1eV energy resolution. Relativistic motion and spin precession of the electron is treated in a concise way by employing a covariant five-dimensional procedure.

  18. Charged gravastars in higher dimensions

    Directory of Open Access Journals (Sweden)

    S. Ghosh


    Full Text Available We explore possibility to find out a new model of gravastars in the extended D-dimensional Einstein–Maxwell space–time. The class of solutions as obtained by Mazur and Mottola of a neutral gravastar [1,2] have been observed as a competent alternative to D-dimensional versions of the Schwarzschild–Tangherlini black hole. The outer region of the charged gravastar model therefore corresponds to a higher dimensional Reissner–Nordström black hole. In connection to this junction conditions, therefore we have formulated mass and the related Equation of State of the gravastar. It has been shown that the model satisfies all the requirements of the physical features. However, overall observational survey of the results also provide probable indication of non-applicability of higher dimensional approach for construction of a gravastar with or without charge from an ordinary 4-dimensional seed as far as physical ground is concerned.

  19. Charged gravastars in higher dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Ghosh, S., E-mail: [Department of Physics, Indian Institute of Engineering Science and Technology, B. Garden, Howrah 711103, West Bengal (India); Rahaman, F., E-mail: [Department of Mathematics, Jadavpur University, Kolkata 700032, West Bengal (India); Guha, B.K., E-mail: [Department of Physics, Indian Institute of Engineering Science and Technology, B. Garden, Howrah 711103, West Bengal (India); Ray, Saibal, E-mail: [Department of Physics, Government College of Engineering and Ceramic Technology, 73 A.C.B. Lane, Kolkata 700010, West Bengal (India)


    We explore possibility to find out a new model of gravastars in the extended D-dimensional Einstein–Maxwell space–time. The class of solutions as obtained by Mazur and Mottola of a neutral gravastar have been observed as a competent alternative to D-dimensional versions of the Schwarzschild–Tangherlini black hole. The outer region of the charged gravastar model therefore corresponds to a higher dimensional Reissner–Nordström black hole. In connection to this junction conditions, therefore we have formulated mass and the related Equation of State of the gravastar. It has been shown that the model satisfies all the requirements of the physical features. However, overall observational survey of the results also provide probable indication of non-applicability of higher dimensional approach for construction of a gravastar with or without charge from an ordinary 4-dimensional seed as far as physical ground is concerned.

  20. ABC's of pion charge exchange

    International Nuclear Information System (INIS)

    Gibbs, W.R.; Kaufmann, W.B.; Siegel, P.B.


    Calculations of pion single charge exchange using the PWIA and DWIA are presented. Emphasis is given to the effects of absorbtion and blocking. A microscopic calculation of the 0 0 excitation and low energy angular distribution is in excellent agreement with the data. A fixed nucleon multiple scattering calculation of the pion double charge exchange reaction is presented. Various valence neutron wave functions are used, and the contributions of different spatial orientations of the last two neutrons to the reaction are examined. The DCX cross section is found to be very sensitive to the inclusion of correlations in the two-neutron wave function. Satisfactory agreement with DCX data on 14 C can be obtained using a nucleonic picture of the nucleus

  1. Display of charged ionizing particles

    International Nuclear Information System (INIS)

    Cano S, D.; Ortiz A, M. D.; Amarillas S, L. E.; Vega C, H. R.


    The human being is exposed to sources of ionizing and non-ionizing radiation, both of natural or anthropogenic origin. None of these, except non-ionizing such as visible light and infrared radiation, can be detected by the sense of sight and touch respectively. The sun emits charged particles with speeds close to the light that interact with the atoms of the gases present in the atmosphere, producing nuclear reactions that in turn produce other particles that reach the surface of the Earth and reach the living beings. On Earth there are natural radioisotopes that, when they disintegrate, emit ionizing radiation that contributes to the dose we receive. A very old system that allows the visualization of the trajectories of the charged ionizing particles is the Fog Chamber that uses a saturated steam that when crossed by particles with mass and charge, as alpha and beta particles produce condensation centers along its path leaves a trace that can be seen. The objective of this work was to build a fog chamber using easily accessible materials. To measure the functioning of the fog chamber, cosmic rays were measured, as well as a source of natural metal uranium. The fog chamber allowed seeing the presence of traces in alcohol vapor that are produced in a random way. Introducing the uranium foil inside the fog chamber, traces of alpha particles whose energy varies from 4 to 5 MeV were observed. (Author)

  2. Charged dust in saturn's magnetosphere

    International Nuclear Information System (INIS)

    Mendis, D.A.; Hill, J.R.; Houpis, H.L.F.


    Gravito-electrodynamic theory of charged dust grains is used to explain a variety of phenomena in those portions of the Saturnian ring system that are known to be dominated by fine (micron- and submicron-sized) dust, and in which collisional forces and Coulomb drag can be neglected. Among the phenomena discussed are the formation and evolution of the rotating near-radial spokes in the B-ring, the formation of waves in the F-ring, the cause of eccentricities of certain isolated ringlets, and the origin and morphology of the broad diffuse E-ring. Several novel processes predicted by the gravitoelectrodynamic theory, including 'magneto-gravitational capture' of exogenic dust by the magnetosphere, '1:1 magneto-gravitational orbital resonances' of charged dust with nearby satellites, and 'gyro-orbital resonances,' are used to explain individual observations. The effect of a ring current associated with this charged dust is also evaluated. Finally, the cosmogonic implications of the magneto-gravitational theory are briefly discussed. While several (although not all) of these processes have been discussed by one or more of the present authors elsewhere, the purpose of this paper is to synthesize all these processes within the framework of gravito-electrodynamics, and also to show its range of applicability within Saturn's ring system

  3. Effective Topological Charge Cancelation Mechanism. (United States)

    Mesarec, Luka; Góźdź, Wojciech; Iglič, Aleš; Kralj, Samo


    Topological defects (TDs) appear almost unavoidably in continuous symmetry breaking phase transitions. The topological origin makes their key features independent of systems' microscopic details; therefore TDs display many universalities. Because of their strong impact on numerous material properties and their significant role in several technological applications it is of strong interest to find simple and robust mechanisms controlling the positioning and local number of TDs. We present a numerical study of TDs within effectively two dimensional closed soft films exhibiting in-plane orientational ordering. Popular examples of such class of systems are liquid crystalline shells and various biological membranes. We introduce the Effective Topological Charge Cancellation mechanism controlling localised positional assembling tendency of TDs and the formation of pairs {defect, antidefect} on curved surfaces and/or presence of relevant "impurities" (e.g. nanoparticles). For this purpose, we define an effective topological charge Δmeff consisting of real, virtual and smeared curvature topological charges within a surface patch Δς identified by the typical spatially averaged local Gaussian curvature K. We demonstrate a strong tendency enforcing Δmeff → 0 on surfaces composed of Δς exhibiting significantly different values of spatially averaged K. For Δmeff ≠ 0 we estimate a critical depinning threshold to form pairs {defect, antidefect} using the electrostatic analogy.

  4. Billing of Household Goods Accessorial Charges

    National Research Council Canada - National Science Library


    The audit objectives were to evaluate the process of submitting bills for household goods accessorial charges for payment, and to evaluate procedures used to conduct prepayment reviews of billed accessorial charges...

  5. 36 CFR 10.2 - Charges. (United States)


    ... CERTAIN WILD ANIMALS § 10.2 Charges. No charge will be made for the animals, but the receiver will be... services of a veterinarian for testing, vaccinating, and treating the animals at the park for communicable...

  6. Complementary surface charge for enhanced capacitive deionization

    NARCIS (Netherlands)

    Gao, X.; Porada, S.; Omosebi, A.; Liu, K.L.; Biesheuvel, P.M.; Landon, J.


    Commercially available activated carbon cloth electrodes are treated using nitric acid and ethylenediamine solutions, resulting in chemical surface charge enhanced carbon electrodes for capacitive deionization (CDI) applications. Surface charge enhanced electrodes are then configured in a CDI

  7. Smart Electric Vehicle Charging Infrastructure Overview

    Energy Technology Data Exchange (ETDEWEB)

    Chynoweth, Joshua; Chung, Ching-Yen; Qiu, Charlie; Chu, Peter; Gadh, Rajit


    WINSmartEV™ is a smart electric vehicle charging system that has been built and is currently in operation. It is a software and network based EV charging system designed and built around the ideas of intelligent charge scheduling, multiplexing (connecting multiple vehicles to each circuit) and flexibility. This paper gives an overview of this smart charging system with an eye toward its unique features and capabilities.



    Harshal Sharma*


    In the modern world, we have often heard a word- wireless charging technology. Actually what is it all about? So this paper is giving you the whole package about wireless charging technology. Wireless charging is a technology through which power is transmitted through an air gap to the electrical devices for the motive of replenishment of energy. At present wireless charging techniques and development of commercial products have provided a promise to address the energy bottleneck of portable ...

  9. Taxa de gestação em fêmeas da raça Holandesa confinadas em free stall, no verão e inverno Gestation rate of Holstein females confined in free stall, during the summer and winter

    Directory of Open Access Journals (Sweden)

    M.F.A. Pires


    Full Text Available A taxa de gestação de vacas em lactação e de novilhas confinadas em free stall foi avaliada durante o inverno e o verão, nos anos de 1993, 1994 e 1995. A temperatura ambiente (TA e a umidade relativa do ar (UR foram acompanhadas diariamente, durante quatro meses de verão (dezembro a março e três meses de inverno (junho a agosto. Em cada estação mediram-se semanalmente às 9, 15 e 21h a temperatura retal (TR e a freqüência respiratória (FR de 50% das vacas em lactação, sorteadas ao acaso, separadas em quatro grupos de acordo com a produção de leite. A TA e o índice de temperatura e umidade (ITU médios foram mais elevados (P The gestation rate was used to evaluate the reproductive performance of dairy cows and heifers confined in a free stall barn during the winter and summer seasons of 1993, 1994 and 1995. The temperature (T and relative humidity (RH were monitored daily during the summer (December, January, February and March and winter (June, July and August. The rectal temperature (RT and respiration rate (RR were measured weekly at 9AM and 3 and 9PM, in each season, in 50% of the animals randomly selected and sorted in four groups based on their milk production. The averages of T and the temperature and humidity index (THI were higher in the summer (25.6ºC e 75.8 than in the winter (19.0ºC e 65.3, while the RH were the same in both seasons (80.0%. The averages of RT and RR were always higher in the summer and at 3PM when compared to 9AM RT and RR (39.47ºC and 64.76 mov/min vs 38.89ºC and 44.21 mov/min. Gestation rate for milking cows was smaller in summer than in the winter. Conversely 85.4% of heifers became pregnant during the summer and 78.5% during the winter season.

  10. Custo e resultados do tratamento de seqüelas de laminite bovina: relato de 112 casos em vacas em lactação no sistema free-stall Results and costs of treatment for bovine laminitis sequelae: study of 112 lameness cases in lactating cows in free-stall system

    Directory of Open Access Journals (Sweden)

    P.M. Ferreira


    Full Text Available Os resultados e o custo do tratamento de seqüelas podais da laminite subclínica são descritos em 112 casos de manqueira em vacas em lactação mantidas no sistema free-stall. As observações feitas durante um ano abrangeram animais de 2,5 a 10 anos de idade, da primeira à sexta lactação e com média de produção de 8.000±2.000kg de leite. O protocolo de tratamento, descrito detalhadamente para cada uma das afecções podais, foi eficiente na reversão de todas elas. O custo total do tratamento para o rebanho foi de US$5,005.23, equivalente ao custo médio de US$44.68 por animal. O tratamento das úlceras de sola foi o mais dispendioso (US$72.58 e o mais demorado (26,8 dias. As afecções mais comuns foram os abscessos de sola e do talão e as lesões da linha branca (64/112 ou 57,2%.The results and costs of treatments of feet sequelae of subclinic dairy cattle laminitis were described in 112 cases of lameness in lactating cows maintained in free stall system. The analyses were performed in an one-year-period using 2.5 to 10 year-old, first to sixth parity cows. Average milk yield was 8,000±2,000kg. The treatment protocol was described in details for each digit lesion and it was very successful to reverse all kinds of lesions. The total treatment cost for the herd was US$5,005.23 and the mean cost/animal was US$44.68. The ulcer treatments were costly (US$72.58 and longer (26.8 days. Sole and heel abscesses and white line disease at the foe (64/112 or 57.2% were most commonly observed.

  11. 7 CFR 1230.76 - Charges. (United States)


    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Charges. 1230.76 Section 1230.76 Agriculture... § 1230.76 Charges. Any assessment not paid when due shall be increased 1.5 percent each month beginning... any unpaid charges previously made pursuant to this section, shall be increased at the same rate on...

  12. 24 CFR 241.1105 - Late charges. (United States)


    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Late charges. 241.1105 Section 241...-Eligibility Requirements § 241.1105 Late charges. The note and security instrument may provide for the lender's collection of a late charge, not to exceed 2 cents for each dollar of each payment to interest or...

  13. 32 CFR 776.81 - Charges. (United States)


    ... 32 National Defense 5 2010-07-01 2010-07-01 false Charges. 776.81 Section 776.81 National Defense... Procedures § 776.81 Charges. (a) If the Rules Counsel determines that there is probable cause to believe that... draft charges alleging violations of this part or of the Code of Judicial Conduct and forward the...

  14. 5 CFR 835.607 - Administrative charges. (United States)


    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Administrative charges. 835.607 Section... (CONTINUED) DEBT COLLECTION Collection of Debts by Federal Tax Refund Offset § 835.607 Administrative charges. All administrative charges incurred in connection with the referral of the debts to the IRS will be...

  15. 46 CFR Sec. 5 - Repatriation charges. (United States)


    ... 46 Shipping 8 2010-10-01 2010-10-01 false Repatriation charges. Sec. 5 Section 5 Shipping MARITIME... Repatriation charges. (a) If it is deemed necessary to repatriate a seaman as a passenger aboard a privately... flat transportation charge of $5.00 per day shall be made for every day spent aboard the repatriating...

  16. 47 CFR 80.95 - Message charges. (United States)


    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Message charges. 80.95 Section 80.95... charges. (a) Except as specified in § 20.15(c) of this chapter with respect to commercial mobile radio service providers, charges must not be made for service of: (1) Any public coast station unless tariffs...

  17. 49 CFR 377.209 - Additional charges. (United States)


    ... 49 Transportation 5 2010-10-01 2010-10-01 false Additional charges. 377.209 Section 377.209... CHARGES Extension of Credit to Shippers by Motor Common Carriers, Water Common Carriers, and Household Goods Freight Forwarders § 377.209 Additional charges. When a carrier— (a) Has collected the amount of...

  18. 5 CFR 2604.702 - Charges. (United States)


    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Charges. 2604.702 Section 2604.702... Reproduction and Mailing of Public Financial Disclosure Reports § 2604.702 Charges. (a) Duplication. Except as... reports will be charged for all forms requested. Where the Office elects to comply, as a matter of...

  19. 31 CFR 10.65 - Supplemental charges. (United States)


    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Supplemental charges. 10.65 Section... INTERNAL REVENUE SERVICE Rules Applicable to Disciplinary Proceedings § 10.65 Supplemental charges. (a) In general. The Director of the Office of Professional Responsibility may file supplemental charges, by...

  20. 49 CFR 1018.92 - Administrative charges. (United States)


    ... 49 Transportation 8 2010-10-01 2010-10-01 false Administrative charges. 1018.92 Section 1018.92 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT... Administrative charges. In accordance with 49 CFR 1018.30, all administrative charges incurred in connection with...

  1. 16 CFR 444.4 - Late charges. (United States)


    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Late charges. 444.4 Section 444.4 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES CREDIT PRACTICES § 444.4 Late charges. (a) In... any deliquency charge on a payment, which payment is otherwise a full payment for the applicable...

  2. 25 CFR 137.3 - Construction charges. (United States)


    ... 25 Indians 1 2010-04-01 2010-04-01 false Construction charges. 137.3 Section 137.3 Indians BUREAU... COSTS, SAN CARLOS INDIAN IRRIGATION PROJECT, ARIZONA § 137.3 Construction charges. Each acre of land in private ownership of said project is hereby charged with $95.25 of construction cost assessable thereto at...

  3. 46 CFR 132.230 - Spare charges. (United States)


    ... 46 Shipping 4 2010-10-01 2010-10-01 false Spare charges. 132.230 Section 132.230 Shipping COAST... Portable and Semiportable Fire Extinguishers § 132.230 Spare charges. (a) Except as provided by paragraph (b) or (c) of this section, each vessel must carry spare charges for 50 percent of the portable fire...

  4. 25 CFR 700.105 - Utility charges. (United States)


    ... 25 Indians 2 2010-04-01 2010-04-01 false Utility charges. 700.105 Section 700.105 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.105 Utility charges. Utility charges means the cost for heat...

  5. 31 CFR 206.9 - Charges. (United States)


    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Charges. 206.9 Section 206.9 Money..., AND OPERATION OF THE CASH MANAGEMENT IMPROVEMENTS FUND § 206.9 Charges. (a) Within 30 days of the effective date of the charge or the appeals decision, an agency must submit appropriate accounting...

  6. 38 CFR 21.9560 - Entitlement charges. (United States)


    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Entitlement charges. 21...) VOCATIONAL REHABILITATION AND EDUCATION Post-9/11 GI Bill Entitlement § 21.9560 Entitlement charges. (a... charges on the principle that an eligible individual who is paid educational assistance for one day of...

  7. 18 CFR 6.5 - Annual charges. (United States)


    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Annual charges. 6.5... ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT SURRENDER OR TERMINATION OF LICENSE § 6.5 Annual charges. Annual charges arising under a license surrendered or terminated shall continue until the effective date...

  8. 7 CFR 956.142 - Interest charges. (United States)


    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Interest charges. 956.142 Section 956.142 Agriculture... VALLEY OF SOUTHEAST WASHINGTON AND NORTHEAST OREGON Rules and Regulations § 956.142 Interest charges. For Walla Walla Sweet Onions handled prior to September 1, the Committee shall impose an interest charge on...

  9. Can Like Charges Attract Each Other? (United States)

    Balta, Nuri


    Electroscopes are sensitive instruments useful for investigations of static electricity. They are devices that are used for detecting whether an object is charged or uncharged. They also determine the type of charge. Their operation is based on the principle of like sign charge repulsion.

  10. 49 CFR 89.39 - Administrative charges. (United States)


    ... 49 Transportation 1 2010-10-01 2010-10-01 false Administrative charges. 89.39 Section 89.39... Referral of Debts to IRS for Tax Refund Offset § 89.39 Administrative charges. In accordance with 4 CFR 102.13, all administrative charges incurred in connection with the referral of the debt to the IRS shall...

  11. 40 CFR 13.36 - Administrative charges. (United States)


    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Administrative charges. 13.36 Section... Referral of Debts to IRS for Tax Refund Offset § 13.36 Administrative charges. In accordance with § 13.11, all administrative charges incurred in connection with the referral of a debt to the IRS shall be...

  12. 29 CFR 1650.207 - Administrative charges. (United States)


    ... 29 Labor 4 2010-07-01 2010-07-01 false Administrative charges. 1650.207 Section 1650.207 Labor... for the Collection of Debts by Federal Tax Refund Offset § 1650.207 Administrative charges. All administrative charges incurred in connection with the referral of a debt to the Treasury and all costs of...

  13. 17 CFR 204.56 - Administrative charges. (United States)


    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Administrative charges. 204.56... DEBT COLLECTION Tax Refund Offset § 204.56 Administrative charges. To the extent permitted by law, all administrative charges incurred in connection with the referral of the debts for tax refund offset will be...

  14. 12 CFR 560.33 - Late charges. (United States)


    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Late charges. 560.33 Section 560.33 Banks and... Investment Powers for Federal Savings Associations § 560.33 Late charges. A Federal savings association may include in a home loan contract a provision authorizing the imposition of a late charge with respect to...

  15. 76 FR 10233 - Schedule of Water Charges (United States)


    ... DELAWARE RIVER BASIN COMMISSION 18 CFR Part 420 Schedule of Water Charges AGENCY: Delaware River..., Part III, Basin Regulations--Water Supply Charges. Accordingly, the Commission's water charging rates..., 2011. Effective Date: February 24, 2011. FOR FURTHER INFORMATION CONTACT: For questions about the water...

  16. Electrostatics with Computer-Interfaced Charge Sensors (United States)

    Morse, Robert A.


    Computer interfaced electrostatic charge sensors allow both qualitative and quantitative measurements of electrostatic charge but are quite sensitive to charges accumulating on modern synthetic materials. They need to be used with care so that students can correctly interpret their measurements. This paper describes the operation of the sensors,…

  17. Parsimonious Charge Deconvolution for Native Mass Spectrometry

    NARCIS (Netherlands)

    Bern, Marshall; Caval, Tomislav; Kil, Yong J; Tang, Wilfred; Becker, Christopher; Carlson, Eric; Kletter, Doron; Sen, K Ilker; Galy, Nicolas; Hagemans, Dominique; Franc, Vojtech; Heck, Albert J R


    Charge deconvolution infers the mass from mass over charge (m/z) measurements in electrospray ionization mass spectra. When applied over a wide input m/z or broad target mass range, charge-deconvolution algorithms can produce artifacts, such as false masses at one-half or one-third of the correct

  18. Invisible Surface Charge Pattern on Inorganic Electrets

    DEFF Research Database (Denmark)

    Wang, Fei; Hansen, Ole


    We propose an easy method to pattern the surface charge of ${\\rm SiO}_{2}$ electrets without patterning the dielectric layer. By eliminating the use of metal guard electrodes, both the charge efficiency and the surface charge stability in humid environments improve. We apply the concept...

  19. Nonextensive electron and ion dust charging currents

    International Nuclear Information System (INIS)

    Amour, Rabia; Tribeche, Mouloud


    The correct nonextensive electron and ion charging currents are presented for the first time based on the orbit motion limited approach. For -1< q<1, where q measures the amount of plasma nonextensivity, the nonextensive electron charging current is expressed in terms of the hypergeometric function. The variable dust charge is expressed in terms of the Lambert function and we take advantage of this transcendental function to investigate succinctly the effects of nonextensive charge carriers. The obtained formulas bring a possibility to build theories on nonlinear collective process in variable charge nonextensive dusty plasmas.

  20. Phased charging and discharging in capacitive desalinatio

    Energy Technology Data Exchange (ETDEWEB)

    Stadermann, Michael; Qu, Yatian; Santiago, Juan G.; Hemmatifar, Ali


    A system combines complete, ultra-thin cells into a monolithic and robust framework necessary for desalination applications which yields orders of magnitude faster desalination. The electrode pairs are located so that a flow of feed water flows through or around the electrode pairs with the flow perpendicular to sequentially applied electric potentials. The system is controlled to charge the series of electrode pairs sequentially or phased. That means the charging of the second electrode pair is delayed with regard to the charging of the first electrode pair and the charging of a third electrode pair is delayed with respect to the charging of the second electrode pair.

  1. Charge transport in organic crystals

    Energy Technology Data Exchange (ETDEWEB)

    Ortmann, Frank


    The understanding of charge transport is one of the central goals in the research on semiconducting crystals. For organic crystals this is particularly complicated due to the strength of the electron-phonon interaction which requires the description of a seamless transition between the limiting cases of a coherent band-transport mechanism and incoherent hopping. In this thesis, charge transport phenomena in organic crystals are studied by theoretical means. A theory for charge transport in organic crystals is developed which covers the whole temperature range from low T, where it reproduces an expression from the Boltzmann equation for band transport, via elevated T, where it generalizes Holstein's small-polaron theory to finite bandwidths, up to high T, for which a temperature dependence equal to Marcus' electron-transfer theory is obtained. Thereby, coherent band transport and thermally induced hopping are treated on equal footing while simultaneously treating the electron-phonon interaction non-perturbatively. By avoiding the approximation of narrow polaron bands the theory allows for the description of large and small polarons and serves as a starting point for computational studies. The theoretical description is completed by using ab initio material parameters for the selected crystals under study. These material parameters are taken from density functional theory calculations for durene, naphthalene, and guanine crystals. Besides the analysis of the transport mechanism, special focus is put on the study of the relationship between mobility anisotropy and structure of the crystals. This study is supported by a 3D-visualization method for the transport channels in such crystals which has been derived in this thesis. (orig.)

  2. Charge balancing fill rate monitor

    International Nuclear Information System (INIS)

    Rothman, J.L.; Blum, E.B.


    A fill rate monitor has been developed for the NSLS storage rings to allow machine tuning over a very large dynamic range of beam current. Synchrotron light, focused on a photodiode, produces a signal proportional to the beam current. A charge balancing circuit processes the diode current, creating an output signal proportional to the current injected into the ring. The unit operates linearly over a dynamic range of 120 dB and can resolve pulses of injected beam as small as 1 μA

  3. On charge-3 cyclic monopoles

    International Nuclear Information System (INIS)

    Braden, H W; D'Avanzo, Antonella; Enolski, V Z


    We determine the spectral curve of charge-3 BPS su(2) monopoles with C 3 cyclic symmetry. The symmetry means that the genus 4 spectral curve covers a (Toda) spectral curve of genus 2. A well adapted homology basis is presented enabling the theta functions and monopole data of the genus 4 curve to be given in terms of genus 2 data. The Richelot correspondence, a generalization of the arithmetic mean, is used to solve for this genus 2 curve. Results of other approaches are compared

  4. Design of Smart Charging Infrastructure Hardware and Firmware Design of the Various Current Multiplexing Charging System

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Ching-Yen; Chu, Peter; Gadh, Rajit


    Currently, when Electric Vehicles (EVs) are charging, they only have the option to charge at a selected current or not charge. When during the day there is a power shortage, the charging infrastructure should have the options to either shut off the power to the charging stations or to lower the power to the EVs in order to satisfy the needs of the grid. There is a need for technology that controls the current being disbursed to these electric vehicles. This paper proposes a design for a smart charging infrastructure capable of providing power to several EVs from one circuit by multiplexing power and providing charge control. The smart charging infrastructure includes the server and the smart charging station. With this smart charging infrastructure, the shortage of energy in a local grid could be solved by our EV management system

  5. Associations of herd- and cow-level factors, cow lying behavior, and risk of elevated somatic cell count in free-stall housed lactating dairy cows. (United States)

    Watters, M E Alexandrea; Meijer, Karin M A; Barkema, Herman W; Leslie, Kenneth E; von Keyserlingk, Marina A G; Devries, Trevor J


    Recent evidence suggests that the risk of intramammary infection in dairy cows is related to lying patterns. The objectives of this study were to quantify the standing and lying behavior of dairy cows milked 3×/d, determine the cow- and herd-level factors associated with these behaviors, and relate these findings to the risk of an elevated somatic cell count (SCC). Five commercial free-stall dairy herds in Eastern Ontario, milking 3×/d, were enrolled in a longitudinal study. Forty Holstein-Friesian cows/herd were randomly selected as focal animals based on days in milk (cow SCC was recorded at the beginning of each period and end of the final period. Elevated SCC (eSCC) was used as an indicator of subclinical mastitis. A new incident eSCC was defined as an individual cow that started the period with a SCC cows for hygiene and lameness. Throughout the course of the study, cows averaged 11.2h/d of lying time, split into 8.6 lying bouts/d that were on average 84.6 min in length. Later lactation cows had longer daily lying times that were split into fewer lying bouts of longer duration than cows earlier in lactation. Lame cows had longer daily lying times and lying bout durations than non-lame cows. Cows with greater milk yield had lower lying times than lower producing cows. Average post-milking standing time across the study herds was 103 min. Manipulation of feed (feed delivery or push-up) by the stockperson, in the hour before milking or shortly thereafter, resulted in the longest post-milking standing times. Over the study period, 48 new eSCC were detected, resulting in a mean herd incidence rate of 0.91 eSCC/cow-year at risk for all study herds. A non-linear relationship between post-milking standing time and eSCC incidence was found; compared to those cows that lie down cows that lie down for the first time >90 min after milking had a lower risk of acquiring a new eSCC. The risk of experiencing an eSCC was also increased in multiparous cows, and in those cows

  6. Sources of nitrous oxide and other climate relevant gases on surface area in a dairy free stall barn with solid floor and outside slurry storage (United States)

    Schmithausen, Alexander J.; Trimborn, Manfred; Büscher, Wolfgang


    Livestock production systems in agriculture are one of the major emitters of greenhouse gases. So far, the focus of research in the dairy farm sector was primarily on ruminal methane (CH4) emissions. Emissions of nitrous oxide (N2O) usually arise from solid manure or in deep litter free stall barns. Release of N2O occurs as a result of interactions between organic material, nitrogen and moisture. Data of N2O emissions from modern dairy barns and liquid manure management systems are rare. Thus, the goal of this research was to determine the main sources of trace gas emissions at the dairy farm level, including N2O. Areas such as the scraped surface area where dry and wet conditions alternate are interesting. Possible sources of trace gases within and outside the barn were localised by measuring trace gas concentration rates from different dairy farm areas (e.g., areas covered with urine and excrement or slurry storage system) via the closed chamber technique. The results indicate typical emission ratios of carbon dioxide (CO2), CH4 and N2O in the various areas to generate comparable equivalent values. Calculated on the basis of nitrogen excretion from dairy cows, total emissions of N2O were much lower from barns than typically measured in fields. However, there were also areas within the barn with individual events and unexpected release factors of N2O concentrations such as urine patches, polluted areas and cubicles. Emission factors of N2O ranged from 1.1 to 5.0 mg m-2 d-1, respectively, for cleaned areas and urine patches. By considering the release factors of these areas and their proportion of the entire barn, total emission rates of 371 CO2-eq. LU-1 a-1, 36 CO2-eq. LU-1 a-1, and 1.7 kg CO2-eq. LU-1 a-1 for CO2, CH4 and N2O, respectively, were measured for the whole barn surface area. The CH4 emissions from surface area were stronger climate relevant comparing to N2O emissions, but compared to CH4 emissions from slurry storage or ruminal fermentation (not

  7. To what extent is a breed-specific database necessary to differentiate meat from pasture-fed and stall-fed lambs using visible spectroscopy? (United States)

    Prache, S; Huang, Y; Andueza, D


    Carotenoid pigments signature in the fat using visible reflectance spectroscopy has shown high potential for distinguishing pasture-fed (P) from stall concentrate-fed (S) lamb carcasses. However, a recent study demonstrated a between-breed variability in the digestive and metabolic fate of carotenoids pigments. The present study was therefore designed to investigate the extent to which this between-breed variability may affect the reliability of diet authentication using visible spectroscopy of the fat. We used 1054 male lambs from three breeds (Romane (ROM), Ile-de-France (OIF) and Limousine (LIM)). The breed-feed breakdown was 148 P and 258 S ROM, 102 P and 92 S OIF and 168 P and 286 S LIM lambs. The reflectance spectrum of perirenal fat was measured at 24 h postmortem at wavelengths between 400 and 700 nm. We quantified light absorption in the 450 to 510 nm area by calculating a traceability index (AVMI 450 to 510) considered as an indicator of the carotenoid concentration in the fat (method 1) and we performed a multivariate analysis over the full set of reflectance data between 400 and 700 nm (method 2). The reliability of method 1 proved very variable across breeds, with a percentage of correctly classified lambs reaching 95.3%, 90.5% and 79.4% in ROM, LIM and OIF lambs, respectively. Despite these between-breeds differences, the threshold of the linear discriminant analysis performed on AVMI 450 to 510 was fairly similar between breeds; when all the data for the three breeds were pooled, the threshold cut-off value was 224 units and the method correctly classified 90.2% of the 1054 lambs. Using the full range of reflectance data (method 2) enabled to significantly increase the proportion of correctly classified lambs for both OIF and LIM breeds, but not for ROM breed. It enabled to correctly classify 96.1%, 94.5% and 94.8% of the ROM, LIM and OIF lambs. The reliability of the discrimination was not significantly different when pooling all lambs for the three

  8. Stalled ERP at Random Textiles (United States)

    Brumberg, Robert; Kops, Eric; Little, Elizabeth; Gamble, George; Underbakke, Jesse; Havelka, Douglas


    Andre Raymond, Executive Vice President of Sales and Marketing for Random Textiles Co. Inc. (RTC), stood in front of the podium to address his team of 70 sales consultants in Las Vegas, NV. The organization had increased market share and achieved record sales over the past three years; however, in the shadow of this success lurked an obstacle that…

  9. Tunisia: high fertility stalls development. (United States)

    Barberis, M


    Despite government policy enacted in 1964 to reduce fertility in order to hasten socioeconomic progress, population pressures continue to impair development in Tunisia. The birth rate fell 20% over the last 2 decades, but this accomplishment has been outweighed by a 50% decline in mortality rates. As a result, the rate of natural population increase has remained relatively constant at 2.5%/year. The initial decline in fertility that followed introduction of the national family planning program appears to have reached a plateau, explained in part by the resurgence of conservatism and religious fundamentalism and the consequent emphasis on women's childbearing roles. Unemployment in rural areas has led to widespread migration and unemployment is as high as 20% in the nonagricultural sector. Many young Tunisians lack adequate educational preparation to enter the labor force; in 1982, 27% of new job entrants could not read or write. The government's plan to decentralize development to stabilize population and achieve equilibrium between regions has been thwarted by the pace of population growth and limited resources. The rural regions where population is increasing the fastest are also the most difficult to reach with family planning programs. On the other hand, there have been some successes in this area when services have been adapted to the lifestyle and traditions of those in these isolated rural villages.

  10. Robots are stalling in Fukushima

    International Nuclear Information System (INIS)



    Whereas robots were expected to be the heroes of the cleaning up of radioactive zones of the Fukushima power station, they fall, lack of autonomy, or stay prisoners of debris. After having briefly described how these robots look like (the characteristics of four models are given, two Japanese and two American robots), this article outlines that they resist quite well to radioactivity, but are rather slow and are not used all at the same time: some are being maintained, some are trapped in debris. Thus, they perform a mission once a week, with finally less than hundred hours of operation for each of them. They are often trapped by debris, their movements are often difficult (notably in front of stairs or of debris), their battery lacks autonomy, and they did not significantly reduce the exposure of humans to radioactivity, but they open perspectives for new devices

  11. Repulsion between oppositely charged planar macroions.

    Directory of Open Access Journals (Sweden)

    YongSeok Jho

    Full Text Available The repulsive interaction between oppositely charged macroions is investigated using Grand Canonical Monte Carlo simulations of an unrestricted primitive model, including the effect of inhomogeneous surface charge and its density, the depth of surface charge, the cation size, and the dielectric permittivity of solvent and macroions, and their contrast. The origin of the repulsion is a combination of osmotic pressure and ionic screening resulting from excess salt between the macroions. The excess charge over-reduces the electrostatic attraction between macroions and raises the entropic repulsion. The magnitude of the repulsion increases when the dielectric constant of the solvent is lowered (below that of water and/or the surface charge density is increased, in good agreement with experiment. Smaller size of surface charge and the cation, their discreteness and mobility are other factors that enhance the repulsion and charge inversion phenomenons.

  12. Charge Injection and Transport in Conjugated Polymers. (United States)

    Malliaras, George


    We will overview the state-of-the-art in our understanding of charge injection and transport in conjugated polymers. We start by discussing the identifying characteristics of this class of materials, especially in relation with their structure and morphology. We follow by reviewing the advantages and limitations of experimental techniques that are used to probe charge transport. We then embark on a discussion of the fundamentals of charge transport in organics. We follow a didactic approach, where we start from transport in crystalline semiconductors and gradually introduce corrections for space charge effects, for the influence of disorder on mobility, for high charge densities, and for electric field-dependent charge densities. We compare with experimental data from polyfluorenes. We then shift our attention to charge injection. We review some of the recent theories and compared their predictions to experimental data, again from polyfluorenes. We close by proposing directions for future work.

  13. Point charges optimally placed to represent the multipole expansion of charge distributions.

    Directory of Open Access Journals (Sweden)

    Ramu Anandakrishnan

    Full Text Available We propose an approach for approximating electrostatic charge distributions with a small number of point charges to optimally represent the original charge distribution. By construction, the proposed optimal point charge approximation (OPCA retains many of the useful properties of point multipole expansion, including the same far-field asymptotic behavior of the approximate potential. A general framework for numerically computing OPCA, for any given number of approximating charges, is described. We then derive a 2-charge practical point charge approximation, PPCA, which approximates the 2-charge OPCA via closed form analytical expressions, and test the PPCA on a set of charge distributions relevant to biomolecular modeling. We measure the accuracy of the new approximations as the RMS error in the electrostatic potential relative to that produced by the original charge distribution, at a distance 2x the extent of the charge distribution--the mid-field. The error for the 2-charge PPCA is found to be on average 23% smaller than that of optimally placed point dipole approximation, and comparable to that of the point quadrupole approximation. The standard deviation in RMS error for the 2-charge PPCA is 53% lower than that of the optimal point dipole approximation, and comparable to that of the point quadrupole approximation. We also calculate the 3-charge OPCA for representing the gas phase quantum mechanical charge distribution of a water molecule. The electrostatic potential calculated by the 3-charge OPCA for water, in the mid-field (2.8 Å from the oxygen atom, is on average 33.3% more accurate than the potential due to the point multipole expansion up to the octupole order. Compared to a 3 point charge approximation in which the charges are placed on the atom centers, the 3-charge OPCA is seven times more accurate, by RMS error. The maximum error at the oxygen-Na distance (2.23 Å is half that of the point multipole expansion up to the octupole

  14. Level 1 Electric Vehicle Charging Stations at the Workplace

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Margaret [Energetics Incorporated, Columbia, MD (United States)


    Level 1 charging (110-120 V) can be a good fit for many workplace charging programs. This document highlights the experiences of a selection of Workplace Charging Challenge partners that use Level 1 charging.

  15. Battery Charge Equalizer with Transformer Array (United States)

    Davies, Francis


    High-power batteries generally consist of a series connection of many cells or cell banks. In order to maintain high performance over battery life, it is desirable to keep the state of charge of all the cell banks equal. A method provides individual charging for battery cells in a large, high-voltage battery array with a minimum number of transformers while maintaining reasonable efficiency. This is designed to augment a simple highcurrent charger that supplies the main charge energy. The innovation will form part of a larger battery charge system. It consists of a transformer array connected to the battery array through rectification and filtering circuits. The transformer array is connected to a drive circuit and a timing and control circuit that allow individual battery cells or cell banks to be charged. The timing circuit and control circuit connect to a charge controller that uses battery instrumentation to determine which battery bank to charge. It is important to note that the innovation can charge an individual cell bank at the same time that the main battery charger is charging the high-voltage battery. The fact that the battery cell banks are at a non-zero voltage, and that they are all at similar voltages, can be used to allow charging of individual cell banks. A set of transformers can be connected with secondary windings in series to make weighted sums of the voltages on the primaries.

  16. Exploring Demand Charge Savings from Commercial Solar

    Energy Technology Data Exchange (ETDEWEB)

    Darghouth, Naim [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Barbose, Galen [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Mills, Andrew [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Wiser, Ryan [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Gagnon, Pieter [National Renewable Energy Lab. (NREL), Golden, CO (United States); Bird, Lori [National Renewable Energy Lab. (NREL), Golden, CO (United States)


    Commercial retail electricity rates commonly include a demand charge component, based on some measure of the customer’s peak demand. Customer-sited solar PV can potentially reduce demand charges, but the magnitude of these savings can be difficult to predict, given variations in demand charge designs, customer loads, and PV generation profiles. Moreover, depending on the circumstances, demand charges from solar may or may not align well with associated utility cost savings. Lawrence Berkeley National Laboratory (Berkeley Lab) and the National Renewable Energy Laboratory (NREL) are collaborating in a series of studies to understand how solar PV can reduce demand charge levels for a variety of customer types and demand charges designs. Previous work focused on residential customs with solar. This study, instead, focuses on commercial customers and seeks to understand the extent and conditions under which rooftop can solar reduce commercial demand charges. To answer these questions, we simulate demand charge savings for a broad range of commercial customer types, demand charge designs, locations, and PV system characteristics. This particular analysis does not include storage, but a subsequent analysis in this series will evaluate demand charge savings for commercial customers with solar and storage.

  17. Thermoelectric, band structure, chemical bonding and dispersion of optical constants of new metal chalcogenides Ba{sub 4}CuGa{sub 5}Q{sub 12} (Q=S, Se)

    Energy Technology Data Exchange (ETDEWEB)

    Reshak, A.H. [New Technologies – Research Center, University of West Bohemia, Univerzitni 8, 306 14 Pilsen (Czech Republic); Center of Excellence Geopolymer and Green Technology, School of Material Engineering, University Malaysia Perlis, 01007 Kangar, Perlis (Malaysia); Azam, Sikander, E-mail: [New Technologies – Research Center, University of West Bohemia, Univerzitni 8, 306 14 Pilsen (Czech Republic)


    The electronic structure and dispersion of optical constants of the Ba{sub 4}CuGa{sub 5}S{sub 12} and Ba{sub 4}CuGa{sub 5}Se{sub 12} compounds were calculated by the first-principles full-potential linearized augmented plane wave (FPLAPW) method. We employed the local density approximation (LDA), generalized gradient approximation (GGA) and Engel–Vosko GGA (EVGGA) to calculate the electronic structures, Fermi surface, thermoelectric, chemical bonding and dispersion of optical constants of these compounds. By investigating the influence of replacing S by Se, it has been found that the charge density around ‘Ga’ is greater in Ba{sub 4}CuGa{sub 5}Se{sub 12} than Ba{sub 4}CuGa{sub 5}S{sub 12}. Fermi surface of Ba{sub 4}CuGa{sub 5}S{sub 12} consists of an electronic sheet only because there is no empty region while Ba{sub 4}CuGa{sub 5}Se{sub 12} contains both holes and electronic sheets because this compound contains both empty and shaded region. As we replace S by Se the heights of the peaks decreases as a results the reflectivity also decreases. It is noticed that the reflectivity is over 68% (60%) for Ba{sub 4}CuGa{sub 5}S{sub 12} (Ba{sub 4}CuGa{sub 5}Se{sub 12}) compounds within the energy range studied. This implies that the material will serve as a good reflector. By replacing S by Se the figure of merit values increases from 0.97 to 1.0, which shows the good thermoelectric behavior of both compounds. - Highlights: • DFT-FPLAPW method used for calculating the properties. • For predicting the chemical bonding the charge density behavior is studied in 2D. • The optical properties were also calculated and analyzed. • The Fermi surface is composed of two bands crossing along the EF level. • The thermoelectric properties have also been calculated.

  18. The charging security study of electric vehicle charging spot based on automatic testing platform (United States)

    Li, Yulan; Yang, Zhangli; Zhu, Bin; Ran, Shengyi


    With the increasing of charging spots, the testing of charging security and interoperability becomes more and more urgent and important. In this paper, an interface simulator for ac charging test is designed, the automatic testing platform for electric vehicle charging spots is set up and used to test and analyze the abnormal state during the charging process. On the platform, the charging security and interoperability of ac charging spots and IC-CPD can be checked efficiently, the test report can be generated automatically with No artificial reading error. From the test results, the main reason why the charging spot is not qualified is that the power supply cannot be cut off in the prescribed time when the charging anomaly occurs.

  19. a Movable Charging Unit for Green Mobility (United States)

    ElBanhawy, E. Y.; Nassar, K.


    Battery swapping of electric vehicles (EVs) matter appears to be the swiftest and most convenient to users. The existence of swapping stations increases the feasibility of distributed energy storage via the electric grid. However, it is a cost-prohibitive way of charging. Early adaptors' preferences of /perceptions about EV system in general, has its inflectional effects on potential users hence the market penetration level. Yet, the charging matter of electric batteries worries the users and puts more pressure on them with the more rigorous planning-ahead they have to make prior to any trip. This paper presents a distinctive way of charging. It aims at making the overall charging process at ease. From a closer look into the literature, most of EVs' populations depend on domestic charge. Domestic charging gives them more confidence and increases the usability factor of the EV system. Nevertheless, they still need to count on the publically available charging points to reach their destination(s). And when it comes to multifamily residences, it becomes a thorny problem as these apartments do not have a room for charging outlets. Having said the irritating charging time needed to fatten the batteries over the day and the minimal average mileage drove daily, hypothetically, home delivery charging (Movable Charging Unit-MCU) would be a stupendous solution. The paper discusses the integration of shortest path algorithm problem with the information about EV users within a metropolitan area, developing an optimal route for a charging unit. This MCU delivers charging till homes whether by swapping batteries or by fast charging facility. Information about users is to be provided by the service provider of the neighbourhood, which includes charging patterns (timing, power capacity). This problem lies under the shortest path algorithms problem. It provides optimal route of charging that in return shall add more reliability and usability values and alleviate the charging

  20. Escova dental e dedeira na remoção da placa bacteriana dental em cães The dental brush and thumb-stall in the removal of the dental plaque in dogs

    Directory of Open Access Journals (Sweden)

    Tânia Berbert Ferreira Lima


    Full Text Available A placa bacteriana é fator primário na formação de gengivite, cálculo dentário, halitose e doença periodontal. Objetivou-se avaliar a quantidade de placa bacteriana dental removida pela escova dental e dedeira. Foram utilizados 60 cães machos e fêmeas de diferentes raças, idade e peso, divididos em dois grupos. O índice Logan & Boyce foi utilizados para quantificar a placa bacteriana antes e após a escovação. Observou-se diferença estatística (p0,05 entre a utilização da escova dental e a dedeira.The dental plaque is the primary factor for gingivitis formation, dental calculus, oral malodor and periodontal disease. To evaluate the amount of dental plaque removed by the dental brush and thumb-stall, 60 male and female dogs of different races, age and weight were divided in two groups and studies. The index of Logan & Boyce was used to quantify the dental plaque before and after the toothbrush. Statistical difference was observed (p 0.05 between the use of the dental brush and the thumb-stall.

  1. Correlations in charged bosons systems

    International Nuclear Information System (INIS)

    Almeida Caparica, A. de.


    The two and three-dimensional charge Bose gas have been studied. In the bidimensional case two different types of interaction were considered: l/r and l n(r). The method of self-consistent-field was applied to these systems, which takes into account the short range correlations between the bosons through a local-field correction. By using self-consistent numerical calculations, the structure factor S(k → ) was determined. The pair-correlation function, the ground-state energy, the pressure of the gas and the spectrum of elementary excitations were obtained from S (k → ). The screening density induced by a fixed charged impurity was calculated. In the high-density limit our calculations reproduce the results given by Bogoliubov's perturbation theory. In the intermediate-density region, corresponding to the strongly coupled systems, the results are in very good agreement with calculations based on HNC approximation as well as Monte Carlo method. The results are compared in several situations with RPA results showing that the self-consistent method is much more accurate. The two-dimensional systems showed to be more correlated than the three-dimensional systems showed to be more correlated than the three-dimensional one; the gas with interaction l/r is also more correlated than the logarithmic one at high densities, but it begins to be less correlated than this one in the low-density region. The thermodynamic functions of the two and three-dimensional systems at finite temperatures near absolute zero are calculated based upon the gas excitation spectra at zero temperature. (author)

  2. Solvation effects on like-charge attraction. (United States)

    Ghanbarian, Shahzad; Rottler, Jörg


    We present results of molecular dynamics simulations of the electrostatic interaction between two parallel charged rods in the presence of divalent counterions. Such polyelectrolytes have been considered as a simple model for understanding electrostatic interactions in highly charged biomolecules such as DNA. Since there are correlations between the free charge carriers, the phenomenon of like charge attraction appears for specific parameters. We explore the role of solvation effects and the resulting deviations from Coulomb's law on the nanoscale on this peculiar phenomenon. The behavior of the force between the charged rods in a simulation with atomistic representation of water molecules is completely different from a model in which water is modeled as a continuum dielectric. By calculating counterion-rodion pair correlation functions, we find that the presence of water molecules changes the structure of the counterion cloud and results in both qualitative and quantitative changes of the force between highly charged polyelectrolytes.

  3. Surface charge measurement by the Pockels effect

    CERN Document Server

    Sam, Y L


    have been observed by applying both impulse and AC voltages to a needle electrode in direct contact with the BSO. AC surface discharge behaviour of polymeric materials bonded to the BSO has also been investigated. The effect of the surrounding environment has been experimentally examined by placing the cell inside a vacuum chamber. Surface charge measurements have been made at various atmospheric pressures. The effect of an electro-negative gas (Sulphur Hexafluoride) on the surface charge distribution has also been investigated. This thesis is concerned with the design and development of a surface charge measurement system using Pockels effect. The measurement of surface charge is important in determining the electrical performance of high voltage insulation materials. The method proposed allows on-line measurement of charge and can generate two-dimensional images that represent the charge behaviour on the surface of the material under test. The measurement system is optical and uses a Pockels crystal as the ...

  4. Multiplicity Distributions and Charged-neutral Fluctuations

    CERN Document Server

    Nayak, Tapan K.; Agnihotri, A.; Ahammed, Z.; Angelis, A.L.S.; Antonenko, V.; Arefev, V.; Astakhov, V.; Avdeitchikov, V.; Awes, T.C.; Baba, P.V.K.S.; Badyal, S.K.; Baldine, A.; Barabach, L.; Barlag, C.; Bathe, S.; Batiounia, B.; Bernier, T.; Bhalla, K.B.; Bhatia, V.S.; Blume, C.; Bock, R.; Bohne, E.M.; Bucher, D.; Buijs, A.; Buis, E.J.; Busching, H.; Carlen, L.; Chalyshev, V.; Chattopadhyay, S.; Chenawi, K.E.; Cherbatchev, R.; Chujo, T.; Claussen, A.; Das, A.C.; Decowski, M.P.; Djordjadze, V.; Donni, P.; Doubovik, I.; Dubey, A.K.; Dutta Majumda, M.R.; Eliseev, S.; Enosawa, K.; Feldmann, H.; Foka, P.; Fokin, S.; Frolov, V.; Ganti, M.S.; Garpman, S.; Gavrishchuk, O.; Geurts, F.J.M.; Ghosh, T.K.; Glasow, R.; Gupta, S.K.; Guskov, B.; Gustafsson, H.A.; Gutbrod, H.H.; Higuchi, R.; Hrivnacova, I.; Ippolitov, M.; Kalechofsky, H.; Kamermans, R.; Kampert, K.H.; Karadjev, K.; Karpio, K.; Kato, S.; Kees, S.; Kim, H.; Kolb, B.W.; Kosarev, I.; Koutcheryaev, I.; Kugler, A.; Kulinich, P.; Kumar, V.; Kurata, M.; Kurita, K.; Kuzmin, N.; Langbein, I.; Lebedev, A.; Lee, Y.Y.; Lohner, H.; Mahapatra, D.P.; Manko, V.; Martin, M.; Maximov, A.; Mehdiyev, Rashid R.; Mgebrichvili, G.; Miake, Y.; Mikhalev, D.; Mishra, G.C.; Miyamoto, Y.; Mohanty, B.; Morrison, Douglas R.O.; Mukhopadhyay, D.S.; Myalkovski, V.; Naef, H.; Nandi, B.K.; Nayak, S.K.; Nayak, T.K.; Neumaier, S.; Nianine, A.; Nikitine, V.; Nikolaev, S.; Nishimura, S.; Nomokov, P.; Nystrand, J.; Obenshain, F.E.; Oskarsson, A.; Otterlund, I.; Pachr, M.; Parfenov, A.; Pavliouk, S.; Peitzmann, T.; Petracek, V.; Plasil, F.; Purschke, M.L.; Raeven, B.; Rak, J.; Raniwala, R.; Raniwala, S.; Ramamurthy, V.S.; Rao, N.K.; Retiere, F.; Reygers, K.; Roland, G.; Rosselet, L.; Roufanov, I.; Rubio, J.M.; Sambyal, S.S.; Santo, R.; Sato, S.; Schlagheck, H.; Schmidt, H.R.; Shabratova, G.; Sibiriak, I.; Siemiarczuk, T.; Sinha, B.C.; Slavine, N.; Soderstrom, K.; Solomey, N.; Sood, G.; Sorensen, S.P.; Stankus, P.; Stefanek, G.; Steinberg, P.; Stenlund, E.; Stuken, D.; Sumbera, M.; Svensson, T.; Trivedi, M.D.; Tsvetkov, A.; Twenhofel, C.; Tykarski, L.; Urbahn, J.; van Eijndhoven, N.; van Heeringen, W.H.; van Nieuwenhuizen, G.J.; Vinogradov, A.; Viyogi, Y.P.; Vodopianov, A.S.; Voros, S.; Vos, M.A.; Wyslouch, B.; Yagi, K.; Yokota, Y.; Young, G.R.; Nayak, Tapan K.


    Results from the multiplicity distributions of inclusive photons and charged particles, scaling of particle multiplicities, event-by-event multiplicity fluctuations, and charged-neutral fluctuations in 158$\\cdot A$ GeV Pb+Pb collisions are presented and discussed. A scaling of charged particle multiplicity as $N_{part}^{1.07\\pm 0.05}$ and photons as $N_{part}^{1.12\\pm 0.03}$ have been observed, indicating violation of naive wounded nucleon model. The analysis of localized charged-neutral fluctuation indicates a model-independent demonstration of non-statistical fluctuations in both charged particles and photons in limited azimuthal regions. However, no correlated charged-neutral fluctuations are observed.

  5. Charge accumulation in lossy dielectrics: a review

    DEFF Research Database (Denmark)

    Rasmussen, Jørgen Knøster; McAllister, Iain Wilson; Crichton, George C


    At present, the phenomenon of charge accumulation in solid dielectrics is under intense experimental study. Using a field theoretical approach, we review the basis for charge accumulation in lossy dielectrics. Thereafter, this macroscopic approach is applied to planar geometries such that the mat......At present, the phenomenon of charge accumulation in solid dielectrics is under intense experimental study. Using a field theoretical approach, we review the basis for charge accumulation in lossy dielectrics. Thereafter, this macroscopic approach is applied to planar geometries...... such that the material parameters which influence charge accumulation are clearly identified; viz. the conductivity, permittivity and dimensions of the insulating media. The two former parameters, together with the applied voltage, govern both the magnitude and polarity of the accumulated charge....

  6. Review of Variable Generation Integration Charges

    Energy Technology Data Exchange (ETDEWEB)

    Porter, K.; Fink, S.; Buckley, M.; Rogers, J.; Hodge, B. M.


    The growth of wind and solar generation in the United States, and the expectation of continued growth of these technologies, dictates that the future power system will be operated in a somewhat different manner because of increased variability and uncertainty. A small number of balancing authorities have attempted to determine an 'integration cost' to account for these changes to their current operating practices. Some balancing authorities directly charge wind and solar generators for integration charges, whereas others add integration charges to projected costs of wind and solar in integrated resource plans or in competitive solicitations for generation. This report reviews the balancing authorities that have calculated variable generation integration charges and broadly compares and contrasts the methodologies they used to determine their specific integration charges. The report also profiles each balancing authority and how they derived wind and solar integration charges.

  7. 12 CFR 535.4 - Late charges. (United States)


    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Late charges. 535.4 Section 535.4 Banks and.... until 7-1-2010) § 535.4 Late charges. (a) In connection with collecting a debt arising out of an... delinquency charge on a payment, which payment is otherwise a full payment for the applicable period and is...

  8. 12 CFR 706.4 - Late charges. (United States)


    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Late charges. 706.4 Section 706.4 Banks and.... until 7-1-10) § 706.4 Late charges. (a) In connection with collecting a debt arising out of an extension... indirectly, to levy or collect any delinquency charge on a payment, which payment is otherwise a full payment...

  9. Fundamentals of shaped charge penetration in concrete

    International Nuclear Information System (INIS)

    Kuklo, R M; Murphy, M J


    We have conducted several studies on the interaction of efp, hemi, and shaped charge jets with concrete targets. Our studies have investigated various liner geometries, liner materials, liner angle variations, liner thickness variations, charge diameter effects, charge standoff effects, high explosive variations, point and wave shaped initiation, monolithic and finite thickness targets, and target obliquity. We describe several relations that correlate the concrete target damage to the warhead and target configuration

  10. Charging for the use of plant varieties


    Kingwell, Ross S.


    Private and many publicly funded plant breeding organisations charge farmers for use of varieties they develop. This article compares four alternative charging mechanisms and outlines responses to these alternatives by farmers and plant breeders. Risk‐averse farmers and breeders are shown to have opposite preferences for charging mechanisms. Results suggest profit‐based or royalties are preferred by farmers whereas breeders prefer area or tonnage‐based royalties. Risk‐sharing arrangements bet...

  11. Application and promotion of wireless charging technology


    Yan, Kaijun


    The aim of this thesis is to study wireless charging technology and analyze the application and promotion of each technology. This technology is based on Faraday’s electromagnetic in 1830s. It is not a new technology but it is developing high speed nowadays. This thesis introduces four mainstream types of wireless charging technology and three main-stream standards, and analyzes their features and development status. Wireless charging technology has been applied to some products, suc...

  12. Bosonic instability of charged black holes

    International Nuclear Information System (INIS)

    Gaina, A.B.; Ternov, I.M.


    The processes of spontaneous and induced production and accumulation of charged bosons on quasibound superradiant levels in the field of Kerr-Newman black hole is analysed. It is shown that bosonic instability may be caused exclusively by the rotation of the black hole. Particulary, the Reissner-Nordstrom configuration is stable. In the case of rotating and charged black hole the bosonic instability may cause an increase of charge of the black hole

  13. Particle creation by charged black holes. (United States)

    Khriplovich, I. B.


    A simple derivation is given for the leading term (n = 1) in the Schwinger formula for the pair creation by a constant electric field. The same approach is applied then to the charged particle production by a charged black hole. In this case, as distinct from that of a constant electric field, the probability of the charged particle production depends essentially on the particle energy. The production rate by black holes is found in the nonrelativistic and ultrarelativistic limits. The range of values for the mass and charge of a black hole is indicated where the discussed mechanism of radiation dominates the Hawking one.

  14. The net charge at interfaces between insulators

    International Nuclear Information System (INIS)

    Bristowe, N C; Littlewood, P B; Artacho, Emilio


    The issue of the net charge at insulating oxide interfaces is briefly reviewed with the ambition of dispelling myths of such charges being affected by covalency and related charge density effects. For electrostatic analysis purposes, the net charge at such interfaces is defined by the counting of discrete electrons and core ion charges, and by the definition of the reference polarization of the separate, unperturbed bulk materials. The arguments are illustrated for the case of a thin film of LaAlO 3 over SrTiO 3 in the absence of free carriers, for which the net charge is exactly 0.5e per interface formula unit, if the polarization response in both materials is referred to zero bulk values. Further consequences of the argument are extracted for structural and chemical alterations of such interfaces, in which internal rearrangements are distinguished from extrinsic alterations (changes of stoichiometry, redox processes), only the latter affecting the interfacial net charge. The arguments are reviewed alongside the proposal of Stengel and Vanderbilt (2009 Phys. Rev. B 80 241103) of using formal polarization values instead of net interfacial charges, based on the interface theorem of Vanderbilt and King-Smith (1993 Phys. Rev. B 48 4442-55). Implications for non-centrosymmetric materials are discussed, as well as for interfaces for which the charge mismatch is an integer number of polarization quanta. (viewpoint)

  15. Central depression of nuclear charge density distribution

    International Nuclear Information System (INIS)

    Chu Yanyun; Ren Zhongzhou; Wang Zaijun; Dong Tiekuang


    The center-depressed nuclear charge distributions are investigated with the parametrized distribution and the relativistic mean-field theory, and their corresponding charge form factors are worked out with the phase shift analysis method. The central depression of nuclear charge distribution of 46 Ar and 44 S is supported by the relativistic mean-field calculation. According to the calculation, the valence protons in 46 Ar and 44 S prefer to occupy the 1d 3/2 state rather than the 2s 1/2 state, which is different from that in the less neutron-rich argon and sulfur isotopes. As a result, the central proton densities of 46 Ar and 44 S are highly depressed, and so are their central charge densities. The charge form factors of some argon and sulfur isotopes are presented, and the minima of the charge form factors shift upward and inward when the central nuclear charge distributions are more depressed. Besides, the effect of the central depression on the charge form factors is studied with a parametrized distribution, when the root-mean-square charge radii remain constant.

  16. Color oscillations and measuring the quark charge

    International Nuclear Information System (INIS)

    Lipkin, H.J.


    Color oscillations analogous to neutrino oscillations but with very high frequency are shown to be present in hadron states below color threshold. Experiments to distinguish between fractionally charged and integrally charged quark models both below and above color threshold are discussed. The instantaneous quark charge is shown to be measurable only in very fast processes determined by the high energy behavior of transition amplitudes well above color threshold. Results from the naive parton model for deep inelastic processes which indicate that real charges of quarks and gluons can be measured are shown to be in error because of neglect of color oscillations and interference terms. (author)

  17. Dosimeter charging and/or reading apparatus

    International Nuclear Information System (INIS)

    Fine, L.T.; Jackson, T.P.


    A device is disclosed for charging and/or reading a capacitor associated with an electrometer incorporated in a radiation dosimeter for the purpose of initializing or ''zeroing'', the dosimeter at the commencement of a radiation measurement cycle or reading it at any time thereafter. The dosimeter electrometer has a movable electrode the position of which is indicative of the charge remaining on the dosimeter capacitor and in turn the amount of radiation incident on the dosimeter since it was zeroed. The charging device also includes means for discharging, immediately upon conclusion of the dosimeter capacitor charging operation, stray capacitance inherent in the dosimeter by reason of its mechanical construction. The charge on the stray capacitance, if not discharged at the conclusion of the dosimeter capacitor charging operation, leaks off during the measurement cycle, introducing measurement errors. A light source and suitable switch means are provided for automatically illuminating the movable electrode of the dosimeter electrometer as an incident to charging the dosimeter capacitor to facilitate reading the initial, or ''zero'', position of the movable electrometer electrode after the dosimeter capacitor has been charged and the stray capacitance discharged. Also included is a manually actuatable switch means, which is operable independently of the aforementioned automatic switch means, to energize the lamp and facilitate reading of the dosimeter without charging

  18. Conductivity maximum in a charged colloidal suspension

    Energy Technology Data Exchange (ETDEWEB)

    Bastea, S


    Molecular dynamics simulations of a charged colloidal suspension in the salt-free regime show that the system exhibits an electrical conductivity maximum as a function of colloid charge. We attribute this behavior to two main competing effects: colloid effective charge saturation due to counterion 'condensation' and diffusion slowdown due to the relaxation effect. In agreement with previous observations, we also find that the effective transported charge is larger than the one determined by the Stern layer and suggest that it corresponds to the boundary fluid layer at the surface of the colloidal particles.

  19. The net charge at interfaces between insulators

    Energy Technology Data Exchange (ETDEWEB)

    Bristowe, N C; Littlewood, P B [Theory of Condensed Matter Group, Cavendish Laboratory, University of Cambridge, J J Thomson Avenue, Cambridge CB3 0HE (United Kingdom); Artacho, Emilio, E-mail: [Department of Earth Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EQ (United Kingdom)


    The issue of the net charge at insulating oxide interfaces is briefly reviewed with the ambition of dispelling myths of such charges being affected by covalency and related charge density effects. For electrostatic analysis purposes, the net charge at such interfaces is defined by the counting of discrete electrons and core ion charges, and by the definition of the reference polarization of the separate, unperturbed bulk materials. The arguments are illustrated for the case of a thin film of LaAlO{sub 3} over SrTiO{sub 3} in the absence of free carriers, for which the net charge is exactly 0.5e per interface formula unit, if the polarization response in both materials is referred to zero bulk values. Further consequences of the argument are extracted for structural and chemical alterations of such interfaces, in which internal rearrangements are distinguished from extrinsic alterations (changes of stoichiometry, redox processes), only the latter affecting the interfacial net charge. The arguments are reviewed alongside the proposal of Stengel and Vanderbilt (2009 Phys. Rev. B 80 241103) of using formal polarization values instead of net interfacial charges, based on the interface theorem of Vanderbilt and King-Smith (1993 Phys. Rev. B 48 4442-55). Implications for non-centrosymmetric materials are discussed, as well as for interfaces for which the charge mismatch is an integer number of polarization quanta. (viewpoint)

  20. Threshold-Based Random Charging Scheme for Decentralized PEV Charging Operation in a Smart Grid. (United States)

    Kwon, Ojin; Kim, Pilkee; Yoon, Yong-Jin


    Smart grids have been introduced to replace conventional power distribution systems without real time monitoring for accommodating the future market penetration of plug-in electric vehicles (PEVs). When a large number of PEVs require simultaneous battery charging, charging coordination techniques have become one of the most critical factors to optimize the PEV charging performance and the conventional distribution system. In this case, considerable computational complexity of a central controller and exchange of real time information among PEVs may occur. To alleviate these problems, a novel threshold-based random charging (TBRC) operation for a decentralized charging system is proposed. Using PEV charging thresholds and random access rates, the PEVs themselves can participate in the charging requests. As PEVs with a high battery state do not transmit the charging requests to the central controller, the complexity of the central controller decreases due to the reduction of the charging requests. In addition, both the charging threshold and the random access rate are statistically calculated based on the average of supply power of the PEV charging system that do not require a real time update. By using the proposed TBRC with a tolerable PEV charging degradation, a 51% reduction of the PEV charging requests is achieved.

  1. Modeling of stored charge in metallized biaxially oriented polypropylene film capacitors based on charging current measurement. (United States)

    Li, Hua; Wang, Bowen; Li, Zhiwei; Liu, De; Lin, Fuchang; Dai, Ling; Zhang, Qin; Chen, Yaohong


    Metallized biaxially oriented polypropylene film (BOPP) capacitors are widely used in pulsed power systems. When the capacitor is used as the energy storage equipment under high electric field, more charges should be provided to maintain the voltage of the capacitor. This should be ascribed to the completion of the slow polarization which may take several hours or even longer. This paper focuses on the stored charge in metallized BOPP film capacitors. The modeling of the stored charge by the equivalent conversion of circuits is conducted to analyse the slow polarization in the BOPP film. The 3-RC network is proposed to represent the time-dependent charge stored in the capacitor. A charging current measurement system is established to investigate the charge storage property of the capacitor. The measurement system can measure the long time charging current with a sampling rate of 300 Hz. The total charge calculated by the charging current indicates that the stored charge in the capacitor under the electric field of 400 V/μm is 13.5% larger than the product of the voltage and the capacitance measured by the AC bridge. The nonlinear effect of the electric field on the slow polarization charge is also demonstrated. And the simulation of charge storage based on the 3-RC network can match well with the trend of the stored charge increasing with the time.

  2. Discrete electrostatic charge transfer by the electrophoresis of a charged droplet in a dielectric liquid. (United States)

    Im, Do Jin; Ahn, Myung Mo; Yoo, Byeong Sun; Moon, Dustin; Lee, Dong Woog; Kang, In Seok


    We have experimentally investigated the electrostatic charging of a water droplet on an electrified electrode surface to explain the detailed inductive charging processes and use them for the detection of droplet position in a lab-on-a-chip system. The periodic bouncing motion of a droplet between two planar electrodes has been examined by using a high-resolution electrometer and an image analysis method. We have found that this charging process consists of three steps. The first step is inductive charge accumulation on the opposite electrode by the charge of a droplet. This induction process occurs while the droplet approaches the electrode, and it produces an induction current signal at the electrometer. The second step is the discharging of the droplet by the accumulated induced charge at the moment of contact. For this second step, there is no charge-transfer detection at the electrometer. The third step is the charging of the neutralized droplet to a certain charged state while the droplet is in contact with the electrode. The charge transfer of the third step is detected as the pulse-type signal of an electrometer. The second and third steps occur simultaneously and rapidly. We have found that the induction current by the movement of a charged droplet can be accurately used to measure the charge of the droplet and can also be used to monitor the position of a droplet under actuation. The implications of the current findings for understanding and measuring the charging process are discussed.

  3. Enhancing charge harvest from microbial fuel cells by controlling the charging and discharging frequency of capacitors. (United States)

    Ren, Shiting; Xia, Xue; Yuan, Lulu; Liang, Peng; Huang, Xia


    Capacitor is a storage device to harvest charge produced from microbial fuel cells (MFCs). In intermittent charging mode, the capacitor is charged by an MFC first, and then discharged through an external resistance. The charge harvested by capacitor is affected by the charging and discharging frequency. In the present study, the effect of the charging and discharging frequency on charge harvest was investigated. At the switching time (ts) of 100 s, the average current over each time segment reached its maximum value (1.59 mA) the earliest, higher than the other tested conditions, and the highest COD removal (63%) was also obtained, while the coulombic efficiency reached the highest of 67% at the ts of 400 s. Results suggested that lower ts led to higher current output and COD removal, but appropriate ts should be selected in consideration of charge recovery efficiency. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. Weak polyelectrolyte complexation driven by associative charging (United States)

    Rathee, Vikramjit S.; Zervoudakis, Aristotle J.; Sidky, Hythem; Sikora, Benjamin J.; Whitmer, Jonathan K.


    Weak polyelectrolytes are relevant for a wide range of fields; in particular, they have been investigated as "smart" materials for chemical separations and drug delivery. The charges on weak polyelectrolytes are dynamic, causing polymer chains to adopt different equilibrium conformations even with relatively small changes to the surrounding environment. Currently, there exists no comprehensive picture of this behavior, particularly where polymer-polymer interactions have the potential to affect charging properties significantly. In this study, we elucidate the novel interplay between weak polyelectrolyte charging and complexation behavior through coupled molecular dynamics and Monte Carlo simulations. Specifically, we investigate a model of two equal-length and oppositely charging polymer chains in an implicit salt solution represented through Debye-Hückel interactions. The charging tendency of each chain, along with the salt concentration, is varied to determine the existence and extent of cooperativity in charging and complexation. Strong cooperation in the charging of these chains is observed at large Debye lengths, corresponding to low salt concentrations, while at lower Debye lengths (higher salt concentrations), the chains behave in apparent isolation. When the electrostatic coupling is long-ranged, we find that a highly charged chain strongly promotes the charging of its partner chain, even if the environment is unfavorable for an isolated version of that partner chain. Evidence of this phenomenon is supported by a drop in the potential energy of the system, which does not occur at the lower Debye lengths where both potential energies and charge fractions converge for all partner chain charging tendencies. The discovery of this cooperation will be helpful in developing "smart" drug delivery mechanisms by allowing for better predictions for the dissociation point of delivery complexes.

  5. Fractionally charged particles and one Dirac charge magnetic monopoles: Are they compatible?

    Directory of Open Access Journals (Sweden)

    V.A. Rubakov


    Full Text Available The simultaneous existence of fractional electric charges and one Dirac charge magnetic monopoles implies the existence of a long-ranged force different from electromagnetism. This may be either unconfined colour or/and some new gauge interaction. In the latter case, ordinary matter could (and, if colour is unbroken, should carry new charge. This charge, however small the coupling constant be, could be experimentally observed in interactions of monopoles with matter. An experiment for checking this possibility is suggested.

  6. The Shaped Charge Concept. Part 2. The History of Shaped Charges (United States)


    the hollow cavity effect and the lined shaped charge effect, Also, M. Neumann (1911) and E. Neumann (1914) (who ame often confused in the literature ...large Gennan holov charge called the " MISTERIE ?" (This is undoubtedl) the MISTEL which evo ved fhom the Beethoven charge discussed earlier). From the...references, with informative abstracts, to all pertinent literature found in books, periodicals, and reports on the subject of shaped charges, particularly

  7. Ultrafast Charge Photogeneration in MEH-PPV Charge-Transfer Complexes

    NARCIS (Netherlands)

    Bakulin, Artem A.; Paraschuk, Dmitry Yu; Pshenichnikov, Maxim S.; van Loosdrecht, Paul H. M.; Corkum, P; DeSilvestri, S; Nelson, KA; Riedle, E; Schoenlein, RW


    Visible-pump - IR-probe spectroscopy is used to study the ultrafast charge dynamics in MEH-PPV based charge-transfer complexes and donor-acceptor blends. Transient anisotropy of the polymer polaron band provides invaluable insights into excitation localisation and charge-transfer pathways.

  8. 12 CFR 7.4001 - Charging interest at rates permitted competing institutions; charging interest to corporate... (United States)


    ... institutions; charging interest to corporate borrowers. 7.4001 Section 7.4001 Banks and Banking COMPTROLLER OF... interest at rates permitted competing institutions; charging interest to corporate borrowers. (a... the law of that state. If state law permits different interest charges on specified classes of loans...

  9. An Elastic Charging Service Fee-Based Load Guiding Strategy for Fast Charging Stations

    Directory of Open Access Journals (Sweden)

    Shu Su


    Full Text Available Compared with the traditional slow charging loads, random integration of large scale fast charging loads will exert more serious impacts on the security of power network operation. Besides, to maximize social benefits, effective scheduling strategies guiding fast charging behaviors should be formulated rather than simply increasing infrastructure construction investments on the power grid. This paper first analyzes the charging users’ various responses to an elastic charging service fee, and introduces the index of charging balance degree to a target region by considering the influence of fast charging loads on the power grid. Then, a multi-objective optimization model of the fast charging service fee is constructed, whose service fee can be further optimized by employing a fuzzy programming method. Therefore, both users’ satisfaction degree and the equilibrium of charging loads can be maintained simultaneously by reasonably guiding electric vehicles (EVs to different fast charging stations. The simulation results demonstrate the effectiveness of the proposed dynamic charging service pricing and the corresponding fast charging load guidance strategy.

  10. 24 CFR 246.21 - Rental charges. (United States)


    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Rental charges. 246.21 Section 246.21 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL Subsidized Insured Projects § 246.21 Rental charges. The Department finds that it is necessary and...

  11. 25 CFR 137.4 - Future charges. (United States)


    ... 25 Indians 1 2010-04-01 2010-04-01 false Future charges. 137.4 Section 137.4 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES REIMBURSEMENT OF CONSTRUCTION COSTS, SAN CARLOS INDIAN IRRIGATION PROJECT, ARIZONA § 137.4 Future charges. The payment of said construction cost...

  12. Liquidity risk charges as a macroprudential tool

    NARCIS (Netherlands)

    Perotti, E.; Suarez, J.


    Liquidity risk charges were proposed in February 2009 as a new macro-prudential tool to discourage systemic risk creation by banks. A new CEPR Policy Insight refines this proposal in order to clarify challenging issues surrounding the implementation of liquidity risk charges.

  13. 24 CFR 246.30 - Rental charges. (United States)


    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Rental charges. 246.30 Section 246.30 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL HUD-Owned Projects § 246.30 Rental charges. The Department has exclusive jurisdiction over the...

  14. 24 CFR 246.5 - Rental charges. (United States)


    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Rental charges. 246.5 Section 246.5 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF... Unsubsidized Insured Projects § 246.5 Rental charges. The Department will generally not interfere in the...

  15. 7 CFR 1488.14 - Interest charges. (United States)


    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Interest charges. 1488.14 Section 1488.14 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF...) Bank Obligations and Repayment § 1488.14 Interest charges. The account receivable assigned to CCC and...

  16. Charging machine for a fast production reactor

    International Nuclear Information System (INIS)

    Artem'ev, L.N.; Kurilkin, V.V.


    Charging machine for a fast production reactor is described. The machine contains charging mechanism, mechanism for positioning fresh fuel and spent fuel assemtlies, storage drums with sockets for control rod assemtlies and collet tongs for control rods. Recharging is conducted by means of ramp channel

  17. 24 CFR 201.31 - Insurance charge. (United States)


    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Insurance charge. 201.31 Section... DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES TITLE I PROPERTY IMPROVEMENT AND MANUFACTURED HOME LOANS Insurance of Loans § 201.31 Insurance charge. (a...

  18. Key performance indicators of charging infrastructure

    NARCIS (Netherlands)

    Helmus, J.; van den Hoed, R.


    The Netherlands are one of the frontrunners in stimulating electric mobility in Europe when it comes to the charging infrastructure density and electric vehicle adoption. Municipalities play an instrumental role in the rollout of public charging infrastructure while they have little insight in the

  19. Stability of a charged, conducting, spheroidal droplet (United States)

    Krappe, H. J.


    The stability of spheroidal, charged, conducting droplets is investigated. The effect of rotation and of external homogeneous electric fields on the equilibrium shape and on the limit of stability is also studied in close analogy to the behavior of volume-charged droplets considered in nuclear physics.


    African Journals Online (AJOL)


    dissociation of these groups, result into a pH dependent surface charge whose density can be measured by acid-base titration. The surface charge density determined by such method is essentially measured relative to the unknown condition of the oxide/liquid interface prior to reagent addition (i.e. at the point of zero ...

  1. Equal Plate Charges on Series Capacitors? (United States)

    Illman, B. L.; Carlson, G. T.


    Provides a line of reasoning in support of the contention that the equal charge proposition is at best an approximation. Shows how the assumption of equal plate charge on capacitors in series contradicts the conservative nature of the electric field. (ZWH)

  2. Binomial distribution for the charge asymmetry parameter

    International Nuclear Information System (INIS)

    Chou, T.T.; Yang, C.N.


    It is suggested that for high energy collisions the distribution with respect to the charge asymmetry z = nsub(F) - nsub(B) is binomial, where nsub(F) and nsub(B) are the forward and backward charge multiplicities. (orig.)

  3. Static Equilibrium Configurations of Charged Metallic Bodies ...

    African Journals Online (AJOL)

    When charged particles are placed on an uncharged metallic body, the charged particles redistribute themselves along the surface of the body until they reach a point or a configuration that no net tangential force is experienced on each particle. That point is referred to as electrostatic equilibrium configuration or simply as ...

  4. Fluctuation charge effects in ionization fronts

    Energy Technology Data Exchange (ETDEWEB)

    Arrayas, Manuel; Trueba, Jose L [Area de Electromagnetismo, Universidad Rey Juan Carlos, Camino del Molino s/n, 28943 Fuenlabrada, Madrid (Spain); Baltanas, J P [Departamento de Fisica Aplicada II, Universidad de Sevilla, Av. Reina Mercedes 2, 41012 Sevilla (Spain)


    In this paper, we study the effects of charge fluctuations on the propagation of both negative and positive ionization fronts in streamer discharges. We show that fronts accelerate when random charge creation events are present. This effect might play a similar role to photoionization in order to make the front move faster.


    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Kei; Gonsalves, Anthony; Lin, Chen; Sokollik, Thomas; Shiraishi, Satomi; Tilborg, Jeroen van; Osterhoff, Jens; Donahue, Rich; Rodgers, David; Smith, Alan; Byrne, Warren; Leemans, Wim


    Cross-calibrations of charge diagnostics are conducted to verify their validity for measuring electron beams produced by laser plasma accelerators (LPAs). Employed diagnostics are a scintillating screen, activation based measurement, and integrating current transformer. The diagnostics agreed within {+-}8 %, showing that they can provide accurate charge measurements for LPAs provided they are used properly.

  6. Theory to determine the critical charge density

    International Nuclear Information System (INIS)

    Vila, F.


    In this paper we theoretically determine the critical charge density in the system earthed metallic sphere-uniformly charged dielectric plane, in presence of earthed surfaces. This is a situation frequently encountered in industrial condition and has a great importance to evaluate the danger of the electrostatic discharges. (author)

  7. Soliton model for elementary electric charge

    International Nuclear Information System (INIS)

    Chepilko, N.M.; Kobushkin, A.P.


    The existence and topological stability of three-dimensional solitons in Klein-Gordon field electrodynamics are proved. The central-symmetric solution to field equations, which can be interpreted as soliton model of elementary electric charge with zero spin, is constructed. The electrostatic soliton rotation is shown to result in the charge having its own magnetic-dipole field. 9 refs.; 2 figs

  8. Low-charge-state RFQ injector

    Energy Technology Data Exchange (ETDEWEB)

    Shepard, K.W.; Kim, J.W.


    Preliminary design work was done for a short, normally-conducting RFQ entrance section for a low-charge-state linac. Early results indicate that a low- frequency (12 MHz) RFQ, operated on a high-voltage platform, and injected with a pre-bunched beam, can provide ATLAS quality beams of ions of charge-to-mass ratio less than 1/132.

  9. a Search for Fractionally Charged Particles. (United States)

    Milner, Richard Gerard

    An ion-source and a charge spectrometer have been built which make it possible to search in solid stable matter for particles with non-integral charge. The ion -source uses a beam of magnetically analyzed 30 keV Ar('+) ions to sputter the sample in an ultra high vacuum environment. The charge spectrometer comprises a 3 MV Pelletron tandem accelerator followed by a 0.2% resolution electrostatic analysis system and a (DELTA)E-E detector system. The entire apparatus has been constructed to be independent of mass over a mass range of 0.2 GeV/c('2) to 250 GeV/c('2). It is assumed that the fractionally charged particle is able to bind an electron. A search has been carried out in samples of niobium and tungsten for fractionally charged particles (FCP) with fractional charge modulo 1/3. In particular, we have looked for Z = N + 1/3 ; N = 0,1... and Z = N + 2/3; N = 0,1. Upper limits have been obtained for the FCP concentration per target atom. These upper limits vary between 1 x 10(' -16) and 3 x 10('--9) depending on the material searched and the charge state examined. Some interesting events have been seen. These are FCP candidates, but they can also be explained as improbable integrally charged events.

  10. 'Stutter timing' for charge decay time measurement

    International Nuclear Information System (INIS)

    Chubb, John; Harbour, John; Pavey, Ian


    The paper describes the approach of 'stutter timing' that has been developed to improve the accuracy of measuring charge decay times in the presence of noise in compact and portable charge decay test instrumentation. The approach involves starting and stopping the timing clock as the noisy signal rises above and falls below the target threshold voltage level.

  11. Charge and Energy Stored in a Capacitor (United States)

    Kraftmakher, Yaakov


    Using a data-acquisition system, the charge and energy stored in a capacitor are measured and displayed during the charging/discharging process. The experiment is usable as a laboratory work and/or a lecture demonstration. (Contains 3 figures.)

  12. Charge exchange between singly ionized helium ions

    International Nuclear Information System (INIS)

    Choi, B.H.; Poe, R.T.; Tang, K.T.


    The plane-wave Born approximation was used to evaluate the charge transfer cross sections for the reaction He + + He + → He ++ + He. The charge transfer cross section is graphed as a function of incident energy and compared with experimental measurements

  13. Precise Charge Measurement For Laser Plasma Accelerators

    International Nuclear Information System (INIS)

    Nakamura, Kei; Gonsalves, Anthony; Lin, Chen; Sokollik, Thomas; Shiraishi, Satomi; van Tilborg, Jeroen; Osterhoff, Jens; Donahue, Rich; Rodgers, David; Smith, Alan; Byrne, Warren; Leemans, Wim


    Cross-calibrations of charge diagnostics are conducted to verify their validity for measuring electron beams produced by laser plasma accelerators (LPAs). Employed diagnostics are a scintillating screen, activation based measurement, and integrating current transformer. The diagnostics agreed within ±8 %, showing that they can provide accurate charge measurements for LPAs provided they are used properly.

  14. Charge stabilization on the electret dosemeter

    International Nuclear Information System (INIS)

    Pela, C.A.; Guilardi, A.J.P.; Ghilardi Netto, T.


    The charge stabilization and how eliminate the humidity effects in electret dosemeter are shown. The charge measure along of time, changing with the humidity is observed. The fabrication of dryness chamber with silica gel for a more adequate use of dosemeter in differents physical conditions of environment is also cited. (C.G.C.) [pt

  15. Slow charge movement in mammalian skeletal muscle. (United States)

    Simon, B J; Beam, K G


    Voltage-dependent charge movements were measured in the rat omohyoid muscle with the three-microelectrode voltage-clamp technique. Contraction was abolished with hypertonic sucrose. The standard (ON-OFF) protocol for eliciting charge movements was to depolarize the fiber from -90 mV to a variable test potential (V) and then repolarize the fiber to -90 mV. The quantity of charge moved saturated at test potentials of approximately 0 mV. The steady state dependence of the amount of charge that moves as a function of test potential could be well fitted by the Boltzmann relation: Q = Qmax/(1 + exp[-(V - V)/k]), where Qmax is the maximum charge that can be moved, V is the potential at which half the charge moves, and k is a constant. At 15 degrees C, these values were Qmax = 28.5 nC/microF, V = -34.2 mV, and k = 8.7 mV. Qmax, k, and V exhibited little temperature dependence over the range 7-25 degrees C. "Stepped OFF" charge movements were elicited by depolarizing the fiber from -90 mV to a fixed conditioning level that moved nearly all the mobile charge (0 mV), and then repolarizing the fiber to varying test potentials. The sum of the charge that moved when the fiber was depolarized directly from -90 mV to a given test potential and the stepped OFF charge that moved when the fiber was repolarized to the same test potential had at all test potentials a value close to Qmax for that fiber. In nearly all cases, the decay phase of ON, OFF, and stepped OFF charge movements could be well fitted with a single exponential. The time constant, tau decay, for an ON charge movement at a given test potential was comparable to tau decay for a stepped OFF charge movement at the same test potential. Tau decay had a bell-shaped dependence on membrane potential: it was slowest at a potential near V (the midpoint of the steady state charge distribution) and became symmetrically faster on either side of this potential. Raising the temperature from 7 to 15 degrees C caused tau decay to

  16. Mass and Charge Measurements on Heavy Ions (United States)

    Sugai, Toshiki


    The relationship between mass and charge has been a crucial topic in mass spectrometry (MS) because the mass itself is typically evaluated based on the m/z ratio. Despite the fact that this measurement is indirect, a precise mass can be obtained from the m/z value with a high m/z resolution up to 105 for samples in the low mass and low charge region under 10,000 Da and 20 e, respectively. However, the target of MS has recently been expanded to the very heavy region of Mega or Giga Da, which includes large particles and biocomplexes, with very large and widely distributed charge from kilo to Mega range. In this region, it is necessary to evaluate charge and mass simultaneously. Recent studies for simultaneous mass and charge observation and related phenomena are discussed in this review. PMID:29302406

  17. Detecting monopole charge via quantum interference transport (United States)

    Dai, Xin; Lu, Haizhou; Yao, Hong

    Topological Weyl and double-Weyl semimetals host different monopole charges in momentum space. How to detect the signature of the monopole charges in quantum transport remains a challenging topic. Here, we reveal the connection between the parity of monopole charge in topological semimetals and the quantum-interference correction to the conductivity. We demonstrate that the parity of monopole charge determines the sign of quantum-interfere correction, with odd and even parity yielding the weak anti-localization and weak localization effect, respectively. This is attributed to the Berry phase difference between time-reversed trajectories circulating the great circle of the Fermi sphere that encloses the monopole charges. From standard Feynman diagram calculations, we further show that the weak-field magnetoconductivity is proportional to +/-√{ B} for double-Weyl semimetals and Weyl semimetals, respectively, which could be verified experimentally.

  18. Electrostatic charge bounds for ball lightning models

    Energy Technology Data Exchange (ETDEWEB)

    Stephan, Karl D [Department of Technology, Texas State University, San Marcos, TX 78666 (United States)], E-mail:


    Several current theories concerning the nature of ball lightning predict a substantial electrostatic charge in order to account for its observed motion and shape (Turner 1998 Phys. Rep. 293 1; Abrahamson and Dinniss 2000 Nature 403 519). Using charged soap bubbles as a physical model for ball lightning, we show that the magnitude of charge predicted by some of these theories is too high to allow for the types of motion commonly observed in natural ball lightning, which includes horizontal motion above the ground and movement near grounded conductors. Experiments show that at charge levels of only 10-15 nC, 3-cm-diameter soap bubbles tend to be attracted by induced charges to the nearest grounded conductor and rupture. We conclude with a scaling rule that can be used to extrapolate these results to larger objects and surroundings.

  19. Electrostatic charge bounds for ball lightning models (United States)

    Stephan, Karl D.


    Several current theories concerning the nature of ball lightning predict a substantial electrostatic charge in order to account for its observed motion and shape (Turner 1998 Phys. Rep. 293 1; Abrahamson and Dinniss 2000 Nature 403 519). Using charged soap bubbles as a physical model for ball lightning, we show that the magnitude of charge predicted by some of these theories is too high to allow for the types of motion commonly observed in natural ball lightning, which includes horizontal motion above the ground and movement near grounded conductors. Experiments show that at charge levels of only 10-15 nC, 3-cm-diameter soap bubbles tend to be attracted by induced charges to the nearest grounded conductor and rupture. We conclude with a scaling rule that can be used to extrapolate these results to larger objects and surroundings.

  20. On equilibrium charge distribution above dielectric surface

    Directory of Open Access Journals (Sweden)

    Yu.V. Slyusarenko


    Full Text Available The problem of the equilibrium state of the charged many-particle system above dielectric surface is formulated. We consider the case of the presence of the external attractive pressing field and the case of its absence. The equilibrium distributions of charges and the electric field, which is generated by these charges in the system in the case of ideally plane dielectric surface, are obtained. The solution of electrostatic equations of the system under consideration in case of small spatial heterogeneities caused by the dielectric surface, is also obtained. These spatial inhomogeneities can be caused both by the inhomogeneities of the surface and by the inhomogeneous charge distribution upon it. In particular, the case of the "wavy" spatially periodic surface is considered taking into account the possible presence of the surface charges.