Sample records for staci emm jason

  1. EMME (Iraq) (United States)

    US Agency for International Development — EMME is a program specific M&E tool for the Iraq Mission that is managed by RTI and provides access to project statuses and success stories for USAID/Iraq Local...

  2. EMME (Indonesia) (United States)

    US Agency for International Development — EMME is a program specific M&E tool for the Indonesia Mission that is managed by RTI and provides access to project statuses and success stories for the USAID...

  3. EMME (Ukraine) (United States)

    US Agency for International Development — EMME is a program specific M&E tool for the Ukraine Mission that is managed by RTI and provides access to project statuses and success stories for USAID/Ukraine...

  4. Construction of STACY (Static Experiment Critical Facility)

    International Nuclear Information System (INIS)

    Murakami, Kiyonobu; Onodera, Seiji; Hirose, Hideyuki


    Two critical assemblies, STACY (Static Experiment Critical Facility) and TRACY (Transient Experiment Critical Facility), were constructed in NUCEF (Nuclear Fuel Cycle Safety Engineering Research Facility) to promote researches on the criticality safety at a reprocessing facility. STACY aims at providing critical data of uranium nitrate solution, plutonium nitrate solution and their mixture while varying concentration of solution fuel, core tank shape and size and neutron reflecting condition. STACY achieved first criticality in February 1995, and passed the licensing inspection by STA (Science and Technology Agency of Japan) in May. After that a series of critical experiments commenced with 10 w/o enriched uranium solution. This report describes the outline of STACY at the end of FY 1996. (author)

  5. Generalized Stacy-Lindley mixture distribution | Maya | Afrika Statistika

    African Journals Online (AJOL)

    In this paper, we introduce a five parameter extension of mixture of two Stacy gamma distributions called generalized Stacy- Lindley mixture distribution. Several statistical properties are derived. Two types of estimation techniques are used for estimating the parameters. Asymptotic confidence interval is also calculated for ...

  6. Reidid Venemaale / Jason Bush

    Index Scriptorium Estoniae

    Bush, Jason


    Korruptsioonist Venemaal Samara piirkonnas, ettevõtte-vaenulikest ülevõtmiskatsetest ja riigiametnike osast selles, Venemaa presidendi algatusest korruptsiooni väljajuurimisel. Vt. samas Jason Bush. BP rasked ajad Venemaal

  7. The Galapagos Jason Curriculum. (United States)

    National Science Teachers Association, Arlington, VA.

    The JASON Curriculum Project materials are designed to prepare teachers and students for an exploration around the Galapagos Islands via satellite transmission of live images and sound. This curriculum package contains five units, 25 lesson plans, and over 50 activities, along with teacher background material, student worksheets and readings, a…

  8. Improvement of fuel sampling device for STACY and TRACY

    Energy Technology Data Exchange (ETDEWEB)

    Hirose, Hideyuki; Sakuraba, Koichi; Onodera, Seiji [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment] [and others


    STACY and TRACY, static and transient experiment facilities in NUCEF, use solution fuel. It is important to analyze accurately fuel composition (uranium enrichment, uranium concentration, nitric acid morality, amount of impurities, radioactivity of FP) for their safety operation and improvement of experimental accuracy. Both STACY and TRACY have the sampling devices to sample fuel solution for that purpose. The previous sampling devices of STACY and TRACY had been designed to dilute fuel sample with nitric acid. Its sampling mechanism could pour fuel sample into sampling vessel by a piston drive of nitric acid in the burette. It was, however, sometimes found that sample fuel solution was diluted by mixing with nitric acid in the burette. Therefore, the sampling mechanism was change into a fixed quantity pump drive which didn`t use nitric acid. The authors confirmed that the performance of the new sampling device was improved by changing sampling mechanism. It was confirmed through the function test that the uncertainty in uranium concentration measurement using the improved sampling device was 0.14%, and less than the designed value of 0.2% (coefficient of variation). (author)

  9. Jason-1 and Jason-2 POD Using GPS (United States)

    Melachroinos, Stavros; Lemoine, Frank G.; Zelensky, Nikita P.; Rowlands, David D.; Luthcke, Scott B.; Beckley, Brian D.


    The Jason-2 satellite, launched in June 2008, is the latest follow-on to the successful Jason-1 altimetry satellite mission launched in December 7, 2001. Both, Jason-2 and Jason-1 are equipped with a GPS dual-frequency receiver, a laser retroreflector array, and a DORIS receiver for precise orbit determination (POD). A series of dynamic and reduced-dynamic Jason-2 orbits computed at NASA GSFC, based on GPS-only data and the std0905 standards, have been completed till cy74through cycle 74 using the IGS05 framework. These orbits, now publicly available, have been shown to agree radially at 1 cm RMS with the GSFC std0905 SLR/DORIS orbits and in comparison with orbits produced by JPL, ESA and CNES. In this paper, we describe the implementation of the IGS08 and repro1 framework for the Jason-2 and Jason-1 GPS POD processing with the NASA GSFC GEODYN software. . In our updated GPS POD, ambiguity fixing and updated time variable and static gravity fields. We also evaluate the implementation of non-tidal and degree-1 loading displacement as forward modeling to the tracking stations. Reduced-dynamic versus dynamic orbit differences are used to characterize the remaining force model errors and TRF instability. In particular, we assess their consistency radially and the stability of the altimeter satellite reference frame in the North/South direction as a proxy to assess the consistency of the reference frame.

  10. Emirates Mars Mission (EMM) Overview (United States)

    Sharaf, Omran; Amiri, Sarah; AlMheiri, Suhail; Alrais, Adnan; Wali, Mohammad; AlShamsi, Zakareyya; AlQasim, Ibrahim; AlHarmoodi, Khuloud; AlTeneiji, Nour; Almatroushi, Hessa; AlShamsi, Maryam; AlAwadhi, Mohsen; McGrath, Michael; Withnell, Pete; Ferrington, Nicolas; Reed, Heather; Landin, Brett; Ryan, Sean; Pramann, Brian


    United Arab Emirates (UAE) has entered the space exploration race with the announcement of Emirates Mars Mission (EMM), the first Arab Islamic mission to another planet, in 2014. Through this mission, UAE is to send an unmanned probe, called Hope probe, to be launched in summer 2020 and reach Mars by 2021 to coincide with UAE's 50th anniversary. Through a sequence of subsequent maneuvers, the spacecraft will enter a large science orbit that has a periapsis altitude of 20,000 km, an apoapsis altitude of 43,000 km, and an inclination of 25 degrees. The mission is designed to (1) characterize the state of the Martian lower atmosphere on global scales and its geographic, diurnal and seasonal variability, (2) correlate rates of thermal and photochemical atmospheric escape with conditions in the collisional Martian atmosphere, and (3) characterize the spatial structure and variability of key constituents in the Martian exosphere. These objectives will be met by four investigations with diurnal variability on sub-seasonal timescales which are (1) determining the three-dimensional thermal state of the lower atmosphere, (2) determining the geographic and diurnal distribution of key constituents in the lower atmosphere, (3) determining the abundance and spatial variability of key neutral species in the thermosphere, and (4) determining the three-dimensional structure and variability of key species in the exosphere. EMM will collect these information about the Mars atmospheric circulation and connections through a combination of three distinct instruments that image Mars in the visible, thermal infrared and ultraviolet wavelengths and they are the Emirates eXploration Imager (EXI), the Emirates Mars InfraRed Spectrometer (EMIRS), and the EMM Mars Ultraviolet Spectrometer (EMUS). EMM has passed its Mission Concept Review (MCR), System Requirements Review (SRR), System Design Review (SDR), and Preliminary Design Review (PDR) phases. The mission is led by Emiratis from Mohammed

  11. Ocean Surface Topography Mission (OSTM) - Jason-2 and Jason-3: Data Documentation Records (NCEI Accession 0118276) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — OSTM/JASON-2 and Jason-3 (scheduled for launch in 2015) are follow-on missions continuing the TOPEX/Poseidon and Jason-1 missions, and are designed to ensure...

  12. Critical experiments on low enriched uranyl nitrate solution with STACY

    International Nuclear Information System (INIS)

    Miyoshi, Yoshinori


    As the STACY started steady operations, systematic criticality data on low enriched uranyl nitrate solution system could be accumulated. Main experimental parameters for the cylindrical tank of 60 cm in diameter were uranium concentration and the reflector condition. Basic data on a simple geometry will be helpful for the validation of the standard criticality safety codes, and for evaluating the safety margin included in the criticality designs. Experiments on the reactivity effects of structural materials such as borated concrete and polyethylene are on schedule next year as the second series of experiments using 10 wt% enriched uranyl solution. Furthermore, neutron interacting experiments with two slab tanks will be performed to investigate the fundamental properties of neutron interaction effects between core tanks. These data will be useful for making more reasonable calculation models and for evaluating the safety margin in the criticality designs for the multiple unit system. (J.P.N.)

  13. Reactor physics tests and benchmark analyses of STACY

    International Nuclear Information System (INIS)

    Miyoshi, Yoshinori; Umano, Takuya


    The Static Experiment Critical Facility, STACY in the Nuclear Fuel Cycle Safety Engineering Research Facility, NUCEF is a solution type critical facility to accumulate fundamental criticality data on uranyl nitrate solution, plutonium nitrate solution and their mixture. A series of critical experiments have been performed for 10 wt% enriched uranyl nitrate solution using a cylindrical core tank. In these experiments, systematic data of the critical height, differential reactivity of the fuel solution, kinetic parameter and reactor power were measured with changing the uranium concentration of the fuel solution from 313 gU/l to 225 gU/l. Critical data through the first series of experiments for the basic core are reported in this paper for evaluating the accuracy of the criticality safety calculation codes. Benchmark calculations of the neutron multiplication factor k eff for the critical condition were made using a neutron transport code TWOTRAN in the SRAC system and a continuous energy Monte Carlo code MCNP 4A with a Japanese evaluated nuclear data library, JENDL 3.2. (J.P.N.)

  14. Annual report of STACY in 1995. 600mm diameter cylindrical core and 10% enriched uranyl nitrate solution

    International Nuclear Information System (INIS)

    Sono, Hiroki; Onodera, Seiji; Hirose, Hideyuki


    STACY, a critical assembly for static criticality safety experiments in NUCEF, had achieved the first criticality on February 23, 1995, with a 600mm diameter cylindrical core tank and 10% enriched uranyl nitrate solution. Since then, 56 experiments were performed with various conditions of fuel concentration and reflecting conditions: bare and water. Operation data of STACY in 1995 are summarized in this report. (author)

  15. Analysis of SLR Targets for JASON

    National Research Council Canada - National Science Library

    Gilbreath, G. Charmaine


    This report provides preliminary results pertaining to the applicability to the JASON program of a retroreflector array designed, built, and space qualified by the Naval Research Laboratory for Low...

  16. NASA 3D Models: Jason 1 (United States)

    National Aeronautics and Space Administration — Jason 1 is an oceanography mission to monitor global ocean circulation, study the ties between the oceans and atmosphere, improve global climate forecasts and...

  17. Critical experiments on STACY homogeneous core containing 10% enriched uranyl nitrate solution

    International Nuclear Information System (INIS)

    Miyoshi, Yoshinori; Yamamoto, Toshihiro; Tonoike, Kotaro; Yamane, Yuichi; Watanabe, Shouichi


    In order to investigate criticality properties of low enriched uranyl nitrate solution treated in the reprocessing facility for LWR fuel cycle, systematic and high precision critical experiments have been performed at the Static Experiment Critical Facility, STACY since 1995. Criticality benchmark data on 10% enriched uranyl nitrate solution for single core and multiple core systems have been accumulated using cylindrical and slab type core tanks. This paper overviews mains data and related criticality calculation results using standard criticality safety calculation code system. (author)

  18. Emirates Mars Mission (EMM) 2020 Overview (United States)

    Amiri, S.; Sharaf, O.; AlMheiri, S.; AlRais, A.; Wali, M.; Al Shamsi, Z.; Al Qasim, I.; Al Harmoodi, K.; Al Teneiji, N.; Almatroushi, H. R.; Al Shamsi, M. R.; Altunaiji, E. S.; Lootah, F. H.; Badri, K. M.; McGrath, M.; Withnell, P.; Ferrington, N.; Reed, H.; Landin, B.; Ryan, S.; Pramann, B.; Brain, D.; Deighan, J.; Chaffin, M.; Holsclaw, G.; Drake, G.; Wolff, M. J.; Edwards, C. S.; Lillis, R. J.; Smith, M. D.; Forget, F.; Fillingim, M. O.; England, S.; Christensen, P. R.; Osterloo, M. M.; Jones, A. R.


    United Arab Emirates (UAE) has entered the space exploration race with the announcement of Emirates Mars Mission (EMM), the first Emirati mission to another planet, in 2014. Through this mission, UAE is to send an unmanned probe, called Hope probe, to be launched in summer 2020 and reach Mars by 2021 to coincide with UAE's 50th anniversary. The mission should be unique, and should aim for novel and significant discoveries that contributed to the ongoing work of the global space science community. EMM has passed its Mission Concept Review (MCR), System Requirements Review (SRR), System Design Review (SDR), Preliminary Design Review (PDR), and Critical Design Review (CDR) phases. The mission is led by the Mohammed Bin Rashid Space Centre (MBRSC), in partnership with the University of Colorado Laboratory for Atmospheric and Space Physics (LASP), University of California Berkeley Space Sciences Laboratory (SSL), and Arizona State University (ASU) School of Earth and Space Exploration. The mission is designed to answer the following three science questions: (1) How does the Martian lower atmosphere respond globally, diurnally, and seasonally to solar forcing? (2) How do conditions throughout the Martian atmosphere affect rates of atmospheric escape? (3) How does the Martian exosphere behave temporally and spatially?. Each question is aligned with three mission objectives and four investigations that study the Martian atmospheric circulation and connections through measurements done using three instruments that image Mars in the visible, thermal infrared and ultraviolet wavelengths. Data will be collected around Mars for a period of an entire Martian year to provide scientists with valuable understanding of the changes to the Martian atmosphere today. The presentation will focus on the overviews of the mission and science objectives, instruments and spacecraft, as well as the ground and launch segments.

  19. Building Multi-Agent Systems Using Jason

    DEFF Research Database (Denmark)

    Boss, Niklas Skamriis; Jensen, Andreas Schmidt; Villadsen, Jørgen


    We provide a detailed description of the Jason-DTU system, including the used methodology, tools as well as team strategy. We also discuss the experience gathered in the contest. In spring 2009 the course “Artificial Intelligence and Multi- Agent Systems” was held for the first time...... on the Technical University of Denmark (DTU). A part of this course was a short introduction to the multi-agent framework Jason, which is an interpreter for AgentSpeak, an agent-oriented programming language. As the final project in this course a solution to the Multi-Agent Programming Contest from 2007, the Gold...

  20. NASA 3D Models: OSTM/Jason-2 (United States)

    National Aeronautics and Space Administration — OSTM/Jason-2's primary payload includes five instruments similar to those aboard Jason-1, along with three experimental instruments. Its main instrument is an...

  1. Working with JASON in the Galapagos. (United States)

    Sigurdsson, Haraldur


    Describes the background and implementation of the JASON Project, which was designed to motivate young students to pursue careers in science and technology by involving them in direct exploration of the Galapagos Islands through more than 60 live, 1-hour television broadcasts. (JJK)

  2. Antimicrobial susceptibility patterns, emm type distribution and genetic diversity of Streptococcus pyogenes recovered in Brazil

    Directory of Open Access Journals (Sweden)

    Glauber P Arêas


    Full Text Available Streptococcus pyogenes is responsible for a variety of infectious diseases and immunological complications. In this study, 91 isolates of S. pyogenes recovered from oropharynx secretions were submitted to antimicrobial susceptibility testing, emm typing and pulsed-field gel electrophoresis (PFGE analysis. All isolates were susceptible to ceftriaxone, levofloxacin, penicillin G and vancomycin. Resistance to erythromycin and clindamycin was 15.4%, which is higher than previous reports from this area, while 20.9% of the isolates were not susceptible to tetracycline. The macrolide resistance phenotypes were cMLSB (10 and iMLSB (4. The ermB gene was predominant, followed by the ermA gene. Thirty-two emm types and subtypes were found, but five (emm1, emm4, emm12, emm22, emm81 were detected in 48% of the isolates. Three new emm subtypes were identified (emm1.74, emm58.14, emm76.7. There was a strong association between emm type and PFGE clustering. A variety of PFGE profiles as well as emm types were found among tetracycline and erythromycin-resistant isolates, demonstrating that antimicrobial resistant strains do not result from the expansion of one or a few clones. This study provides epidemiological data that contribute to the development of suitable strategies for the prevention and treatment of such infections in a poorly studied area.


    Directory of Open Access Journals (Sweden)

    L. A. Burova


    Full Text Available In this paper the nephritogenic activity of Streptococcus pyogenes genotype emm1 and emm12 clinical isolates from scarlet fever patients and healthy children was considered. As earlier established, strains of these types differ in Fc-binding profile, interacting with native IgG and immune complexes (IC, respectively. As expected, all the type emm1 strains bound native IgG; besides, ICs interacted only with strains from patients but not with those from carriers. In contrast, all type emm12 strains appeared to be negative for native IgG, whereas ICs were bound by strains from patients exclusively. None of the tested strains bound IgG3. By immunization of rabbits, binding of native IgG as well as ICs was associated with increasing of anti-IgG antibodies titer, formation of ICs, «crescent» deposition of IgG and C3-complement, local production of the proinflammatory cytokine TNFα, аnd also with accumulation of lymphocytes in kidney tissue. These signs indicated immune inflammation, leading to experimental membrane-proliferative glomerulonephritis (PSGN. It is known that PSGN development depends on IC-binding by tissue FcγR, on complement activation as well as on tissue infiltration by macrophages/monocytes. According to the data of morphometric evaluation the nephritogenic activity of the type emm12 strains exceeded those of type emm1. On testing of three IC-binding emm12 strains in six rabbits, typical PSGN developed in 5 of them and an abortive process in 1 animal. In case of five IgG-binding type emm1 strains, out of ten rabbits full-blown PSGN was observed only in 3 of them, but abortive changes in 5 and negative result in 2 animals. No pathologic changes were elicited by the «carrier» strains of either genotype; the inability of these to bind ICs, according to literature data, could be explained by mutation in the Mga-regulator gene thereby impeding M-proteins synthesis. We conclude that isolation of type emm12 IC-binding strains at acute

  4. Changing epidemiology of Streptococcus pyogenes emm types and associated invasive and noninvasive infections in Southern Taiwan. (United States)

    Su, Yu-Fang; Wang, Shih-Min; Lin, Ya-Lan; Chuang, Woei-Jer; Lin, Yee-Shin; Wu, Jiunn-Jong; Lin, Ming T; Liu, Ching-Chuan


    A total of 242 isolates were recovered from 76 patients with invasive diseases, 89 with scarlet fever, and 77 with pharyngitis. The most frequent emm types were types 12 (43.4%), 4 (18.2%), and 1 (16.9%). emm12 reemerged in 2005 and peaked in 2007. emm11 was recovered only from patients with invasive disease.

  5. Plan-Belief Revision in Jason

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt; Villadsen, Jørgen


    When information is shared between agents of unknown reliability, it is possible that their belief bases become inconsistent. In such cases, the belief base must be revised to restore consistency, so that the agent is able to reason. In some cases the inconsistent information may be due to use of...... of incorrect plans. We extend work by Alechina et al. to revise belief bases in which plans can be dynamically added and removed. We present an implementation of the algorithm in the AgentSpeak implementation Jason....

  6. Isolation of Streptococcus pyogenes from children with pharyngitis and emm type analysis. (United States)

    Khosravi, Azar D; Ebrahimifard, Nasim; Shamsizadeh, Ahmad; Shoja, Saeed


    The group A streptococcus (GAS) M protein, encoded by the emm gene, acts as a major virulence factor. Emm-typing is the GAS gold standard molecular typing and is based on the DNA sequence of the nucleotides of the emm gene. The aim of the present study was to isolate GAS from patients and to detect the emm types of the isolates using emm typing. A total of 1000 throat samples were collected from patients with pharyngitis referred to Aboozar Children's Hospital in Ahvaz, Iran. We performed antimicrobial susceptibility testing on all isolates using the Kirby-Bauer disk diffusion method. Additionally, amplification of the emm gene was performed using polymerase chain reaction using the standard primers and described protocol. From all throat samples screened, 25 isolates (2.5%) were identified as GAS. Antibiotic susceptibility testing revealed that all the GAS isolates were susceptible to penicillin and erythromycin, but 44% showed resistance to vancomycin. Based on polymerase chain reaction for the emm gene, the obtained emm types were: emm-3, observed in 20 isolates (80%); emm-1 observed in four isolates (16%); and emm-75 observed in one isolate (4%). The result of the present study showed that penicillin and erythromycin are still the most effective antibiotics against the organism. The emm typing revealed that emm type-3 was detected in most of the isolates from patients with purulent pharyngitis. On the basis of the findings of this study, we may conclude that emm typing provides new insights on the genetic diversity of the M proteins, and is of demonstrable value for molecular studies of GAS. Copyright © 2016. Published by Elsevier Taiwan LLC.

  7. Seven-year surveillance of emm types of pediatric Group A streptococcal pharyngitis isolates in Western Greece.

    Directory of Open Access Journals (Sweden)

    George A Syrogiannopoulos

    Full Text Available BACKGROUND: An experimental 26-valent M protein Group A streptococcal (GAS vaccine has entered clinical studies. Pharyngeal GAS emm type surveillances in different areas and time-periods enhance the understanding of the epidemiology of GAS pharyngitis. Moreover, these surveillances, combined with the data on GAS invasive disease, can play a significant role in the formulation of multivalent type-specific vaccines. METHODS: During a 7-year period (1999-2005, 2408 GAS isolates were recovered from consecutive children with pharyngitis in Western Greece. The overall macrolide resistance rate was 22.8%. Along the study period we noted a tendency towards significantly decreased rates of resistance, with the lowest rates occurring in 2002 (15.3%, 2003 (15% and 2004 (16.7%. A random sample of isolates from each year, 338 (61.7% of the 548 macrolide-resistant and 205 (11% of the macrolide-susceptible, underwent molecular analysis, including emm typing. RESULTS: The 543 typed isolates had 28 different emm types. A statistically significant association was found between macrolide resistance and emm4, emm22 and emm77, whereas emm1, emm3, emm6, emm12, emm87 and emm89 were associated with macrolide susceptibility. A significant yearly fluctuation was observed in emm4, emm28 and emm77. The most common macrolide-resistant GAS were emm77 isolates harboring erm(A, either alone or in combination with mef(A, emm4 carrying mef(A, emm28 possessing erm(B, emm75 carrying mef(A, emm12 harboring mef(A and emm22 carrying erm(A. We estimated that 82.8% of the isolates belonged to emm types included in the novel 26-valent M protein vaccine. The vaccine coverage rate was determined mainly by the increased frequency of nonvaccine emm4 isolates. CONCLUSIONS: A limited number of emm types dominated among macrolide-susceptible and macrolide-resistant GAS isolates. We observed seasonal fluctuations, which were significant for emm4, emm28 and emm77. This type of data can serve as

  8. Isolation of Streptococcus pyogenes from children with pharyngitis and emm type analysis

    Directory of Open Access Journals (Sweden)

    Azar D. Khosravi


    Conclusion: The result of the present study showed that penicillin and erythromycin are still the most effective antibiotics against the organism. The emm typing revealed that emm type-3 was detected in most of the isolates from patients with purulent pharyngitis. On the basis of the findings of this study, we may conclude that emm typing provides new insights on the genetic diversity of the M proteins, and is of demonstrable value for molecular studies of GAS.

  9. Epidemiology Analysis of Streptococcus pyogenes in a Hospital in Southern Taiwan by Use of the Updated emm Cluster Typing System. (United States)

    Chiang-Ni, Chuan; Zheng, Po-Xing; Wang, Shu-Ying; Tsai, Pei-Jane; Chuang, Woei-Jer; Lin, Yee-Shin; Liu, Ching-Chuan; Wu, Jiunn-Jong


    emm typing is the most widely used molecular typing method for the human pathogen Streptococcus pyogenes (group A streptococcus [GAS]). emm typing is based on a small variable region of the emm gene; however, the emm cluster typing system defines GAS types according to the nearly complete sequence of the emm gene. Therefore, emm cluster typing is considered to provide more information regarding the functional and structural properties of M proteins in different emm types of GAS. In the present study, 677 isolates collected between 1994 and 2008 in a hospital in southern Taiwan were analyzed by the emm cluster typing system. emm clusters A-C4, E1, E6, and A-C3 were the most prevalent emm cluster types and accounted for 67.4% of total isolates. emm clusters A-C4 and E1 were associated with noninvasive diseases, whereas E6 was significantly associated with both invasive and noninvasive manifestations. In addition, emm clusters D4, E2, and E3 were significantly associated with invasive manifestations. Furthermore, we found that the functional properties of M protein, including low fibrinogen-binding and high IgG-binding activities, were correlated significantly with invasive manifestations. In summary, the present study provides updated epidemiological information on GAS emm cluster types in southern Taiwan. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  10. Characterisation of clinically isolated Streptococcus pyogenes from balanoposthitis patients, with special emphasis on emm89 isolates. (United States)

    Hasegawa, Tadao; Hata, Nanako; Matsui, Hideyuki; Isaka, Masanori; Tatsuno, Ichiro


    Streptococcus pyogenes causes a variety of diseases, such as pharyngitis and toxic shock syndrome. In addition, this bacterium is a causative agent of balanoposthitis. To reveal the bacteriological characteristics of the isolates from balanoposthitis patients, we analysed 47 isolates. In addition, novel clade genotype emm89 S. pyogenes isolates have been reported to be spreading worldwide recently. Hence, we further analysed eight emm89 isolates. A drug susceptibility experiment was performed and emm types were determined. More detailed experiments, such as PCR analysis for the presence of virulence-associated genes and MLST analysis, were performed especially using emm89 isolates. All isolates were sensitive to ampicillin, but 34 % of the isolates were resistant to at least one antibiotic. The emm types of the isolates varied, with emm89 and emm11 being the most prevalent, but the emm1 type was not detected. The analysis of emm89 isolates revealed that drug susceptibilities varied. All isolates were negative for the hasABC gene and produced active NADase that are characteristics of novel clade genotype emm89 S. pyogenes. MLST analysis demonstrated that six isolates were of the ST101 type, the most predominant type reported thus far, but two isolates were of the ST646 type. According to the PCR analysis used to determine the presence of streptococcal pyrogenic exotoxin-related genes, the six ST101 isolates were further classified into four groups. These results suggest that balanoposthitis is caused by a variety of types of S. pyogenes, with novel clade genotype emm89 isolates playing a role in balanoposthitis infections in Japan.

  11. Gridded 5-day mean sea surface height anomaly and significant wave height from Jason-1 and OSTM/Jason-2 satellites (NODC Accession 0065055) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains the gridded 5-day mean sea surface height anomaly (SSHA) and Ku Band significant wave height (SWH-KU) observed from Jason-1 and OSTM/Jason-2...

  12. Clustered Regularly Interspaced Short Palindromic Repeats Are emm Type-Specific in Highly Prevalent Group A Streptococci. (United States)

    Zheng, Po-Xing; Chan, Yuen-Chi; Chiou, Chien-Shun; Chiang-Ni, Chuan; Wang, Shu-Ying; Tsai, Pei-Jane; Chuang, Woei-Jer; Lin, Yee-Shin; Liu, Ching-Chuan; Wu, Jiunn-Jong


    Clustered regularly interspaced short palindromic repeats (CRISPR) are the bacterial adaptive immune system against foreign nucleic acids. Given the variable nature of CRISPR, it could be a good marker for molecular epidemiology. Group A streptococcus is one of the major human pathogens. It has two CRISPR loci, including CRISPR01 and CRISPR02. The aim of this study was to analyze the distribution of CRISPR-associated gene cassettes (cas) and CRISPR arrays in highly prevalent emm types. The cas cassette and CRISPR array in two CRISPR loci were analyzed in a total of 332 strains, including emm1, emm3, emm4, emm12, and emm28 strains. The CRISPR type was defined by the spacer content of each CRISPR array. All strains had at least one cas cassette or CRISPR array. More than 90% of the spacers were found in one emm type, specifically. Comparing the consistency between emm and CRISPR types by Simpson's index of diversity and the adjusted Wallace coefficient, CRISPR01 type was concordant to emm type, and CRISPR02 showed unidirectional congruence to emm type, suggesting that at least for the majority of isolates causing infection in high income countries, the emm type can be inferred from CRISPR analysis, which can further discriminate isolates sharing the same emm type.

  13. Clustered Regularly Interspaced Short Palindromic Repeats Are emm Type-Specific in Highly Prevalent Group A Streptococci.

    Directory of Open Access Journals (Sweden)

    Po-Xing Zheng

    Full Text Available Clustered regularly interspaced short palindromic repeats (CRISPR are the bacterial adaptive immune system against foreign nucleic acids. Given the variable nature of CRISPR, it could be a good marker for molecular epidemiology. Group A streptococcus is one of the major human pathogens. It has two CRISPR loci, including CRISPR01 and CRISPR02. The aim of this study was to analyze the distribution of CRISPR-associated gene cassettes (cas and CRISPR arrays in highly prevalent emm types. The cas cassette and CRISPR array in two CRISPR loci were analyzed in a total of 332 strains, including emm1, emm3, emm4, emm12, and emm28 strains. The CRISPR type was defined by the spacer content of each CRISPR array. All strains had at least one cas cassette or CRISPR array. More than 90% of the spacers were found in one emm type, specifically. Comparing the consistency between emm and CRISPR types by Simpson's index of diversity and the adjusted Wallace coefficient, CRISPR01 type was concordant to emm type, and CRISPR02 showed unidirectional congruence to emm type, suggesting that at least for the majority of isolates causing infection in high income countries, the emm type can be inferred from CRISPR analysis, which can further discriminate isolates sharing the same emm type.

  14. Annual report of STACY operation in F.Y. 1997. 280mm thickness slab core {center_dot} 10% enriched uranyl nitrate solution

    Energy Technology Data Exchange (ETDEWEB)

    Onodera, Seiji; Sono, Hiroki; Hirose, Hideyuki [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment] [and others


    Fifty-three times critical experiments (run number R0104 to R0156) with STACY in NUCEF, were performed in F.Y. 1997. During these experiments, 10% enriched uranyl nitrate solution was used as fuel, and core configuration was 280mm thickness and 1.5m height slab core tank with various rectangular solid reflectors; ordinary or borated concrete, polyethylene and so on, to measure mainly reactivity worth by changes of reflecting material and its thickness. Operation data of STACY in F.Y. 1997 are summarized in this report. (author)

  15. Superantigenic activity of emm3 Streptococcus pyogenes is abrogated by a conserved, naturally occurring smeZ mutation.

    Directory of Open Access Journals (Sweden)

    Claire E Turner

    Full Text Available Streptococcus pyogenes M/emm3 strains have been epidemiologically linked with enhanced infection severity and risk of streptococcal toxic shock syndrome (STSS, a syndrome triggered by superantigenic stimulation of T cells. Comparison of S. pyogenes strains causing STSS demonstrated that emm3 strains were surprisingly less mitogenic than other emm-types (emm1, emm12, emm18, emm28, emm87, emm89 both in vitro and in vivo, indicating poor superantigenic activity. We identified a 13 bp deletion in the superantigen smeZ gene of all emm3 strains tested. The deletion led to a premature stop codon in smeZ, and was not present in other major emm-types tested. Expression of a functional non-M3-smeZ gene successfully enhanced mitogenic activity in emm3 S. pyogenes and also restored mitogenic activity to emm1 and emm89 S. pyogenes strains where the smeZ gene had been disrupted. In contrast, the M3-smeZ gene with the 13 bp deletion could not enhance or restore mitogenicity in any of these S. pyogenes strains, confirming that M3-smeZ is non-functional regardless of strain background. The mutation in M3-smeZ reduced the potential for M3 S. pyogenes to induce cytokines in human tonsil, but not during invasive infection of superantigen-sensitive mice. Notwithstanding epidemiological associations with STSS and disease severity, emm3 strains have inherently poor superantigenicity that is explained by a conserved mutation in smeZ.

  16. Genome sequence analysis of emm89 Streptococcus pyogenes strains causing infections in Scotland, 2010-2016. (United States)

    Beres, Stephen B; Olsen, Randall J; Ojeda Saavedra, Matthew; Ure, Roisin; Reynolds, Arlene; Lindsay, Diane S J; Smith, Andrew J; Musser, James M


    Strains of type emm89 Streptococcus pyogenes have recently increased in frequency as a cause of human infections in several countries in Europe and North America. This increase has been molecular epidemiologically linked with the emergence of a new genetically distinct clone, designated clade 3. We sought to extend our understanding of this epidemic behavior by the genetic characterization of type emm89 strains responsible in recent years for an increased frequency of infections in Scotland. We sequenced the genomes of a retrospective cohort of 122 emm89 strains recovered from patients with invasive and noninvasive infections throughout Scotland during 2010 to 2016. All but one of the 122 emm89 infection isolates are of the recently emerged epidemic clade 3 clonal lineage. The Scotland isolates are closely related to and not genetically distinct from recent emm89 strains from England, they constitute a single genetic population. The clade 3 clone causes virtually all-contemporary emm89 infections in Scotland. These findings add Scotland to a growing list of countries of Europe and North America where, by whole genome sequencing, emm89 clade 3 strains have been demonstrated to be the cause of an ongoing epidemic of invasive infections and to be genetically related due to descent from a recent common progenitor.

  17. High prevalence of fluoroquinolone-nonsusceptible Streptococcus pyogenes emm12 in Taiwan. (United States)

    Lin, Jiun-Nong; Chang, Lin-Li; Lai, Chung-Hsu; Huang, Yi-Han; Chen, Wei-Fang; Yang, Chih-Hui; Hsu, Janine; Lin, Hsi-Hsun; Chen, Yen-Hsu


    Fluoroquinolone-nonsusceptible Streptococcus pyogenes has rapidly emerged in several countries. The aim of this study was to survey the epidemiology and molecular characteristics of fluoroquinolone-nonsusceptible S. pyogenes in Taiwan. A total of 350 consecutive S. pyogenes isolates were collected between January 2005 and December 2012, including 152 (43.4%) invasive and 198 (56.6%) noninvasive isolates. Thirty-nine isolates (11.1%) of S. pyogenes were nonsusceptible to fluoroquinolones, including one emm1/ST28, 4 emm4/ST39, 33 emm12/ST36, and 1 emm87/ST62. Of all the isolates, emm12 (50%) demonstrated the highest prevalence of fluoroquinolone nonsusceptibility. Alterations of Ser79Phe and Ala12Val in ParC were the most frequently mutations in fluoroquinolone-nonsusceptible S. pyogenes isolates. There were no amino acid substitutions in GyrB, and 1 emm87 isolate exhibited 3 nonsynonymous mutations in ParE. Our study reveals the emergence of fluoroquinolone-nonsusceptible S. pyogenes emm12/ST36 in Taiwan. Regular surveillance of fluoroquinolone susceptibility in S. pyogenes is suggested. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Epidemiology and emm types of invasive group A streptococcal infections in Finland, 2008-2013. (United States)

    Smit, P W; Lindholm, L; Lyytikäinen, O; Jalava, J; Pätäri-Sampo, A; Vuopio, J


    Invasive Streptococcus pyogenes (group A streptococcus, GAS) infections are a major global cause of morbidity and mortality. We analysed the surveillance data on invasive GAS and the microbiological characteristics of corresponding isolates to assess the incidence and emm type distribution of invasive GAS infections in Finland. Cases defined as patients with isolations of blood and cerebrospinal fluid S. pyogenes are mandatorily notified to the National Infectious Disease Registry and sent to the national reference laboratory for emm typing. Antimicrobial data were collected through the network including all clinical microbiology laboratories. Pulsed-field gel electrophoresis (PFGE) analysis was performed to assess clonality. In total, 1165 cases of invasive GAS were reported in Finland during 2008-2013; the median age was 52 years (range, 0-100) and 54% were male. The overall day 7 case fatality rate was 5.1% (59 cases). The average annual incidence was 3.6 cases per 100,000 population. A total of 1122 invasive GAS isolates (96%) were analysed by emm typing; 72 different emm types were identified, of which emm28 (297 isolates, 26%), emm89 (193 isolates, 12%) and emm1 (132 isolates, 12%) were the most common types. During 2008-2013, an increase of erythromycin resistance (1.9% to 8.7%) and clindamycin (0.9% to 9.2%) was observed. This resistance increase was in parallel with the introduction of a novel clone emm33 into Finland. The overall incidence of invasive GAS infections remained stable over the study period in Finland. We identified clonal spread of macrolide-resistant invasive emm33 GAS type, highlighting the importance of molecular surveillance.

  19. Ocean Surface Topography Mission (OSTM) /Jason-2 Data Collection, 2008-present (NODC Accession 0118277) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — OSTM/JASON-2 is a follow-on mission continuing the TOPEX/Poseidon and Jason-1, and is designed to ensure continuity of high quality measurements for ocean science...

  20. Ocean Surface Topography Mission (OSTM) /Jason-2: Level-2 Geophysical Data Records (GDR) (NODC Accession 0043269) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — OSTM/JASON-2 is a follow-on mission continuing the TOPEX/Poseidon and Jason-1, and is designed to ensure continuity of high quality measurements for ocean science...

  1. The JASON Project: Ghosts of Ancient Fighting Ships. (United States)

    Carey, Helen H.; Greenberg, Judith E.


    Describes the JASON project, a joint project of the National Council for Social Studies and the National Science Teachers Association. Provides a sample lesson on the Punic Wars in which students study the relationship between shipbuilding and Rome's ascendancy to power. Explores the links among technology, science, and social studies. (RW)

  2. Status of Precise Orbit Determination for Jason-2 Using GPS (United States)

    Melachroinos, S.; Lemoine, F. G.; Zelensky, N. P.; Rowlands, D. D.; Pavlis, D. E.


    The JASON-2 satellite, launched in June 2008, is the latest follow-on to the successful TOPEX/Poseidon (T/P) and JASON-I altimetry missions. JASON-2 is equipped with a TRSR Blackjack GPS dual-frequency receiver, a laser retroreflector array, and a DORIS receiver for precise orbit determination (POD). The most recent time series of orbits computed at NASA GSFC, based on SLR/DORIS data have been completed using both ITRF2005 and ITRF2008. These orbits have been shown to agree radially at 1 cm RMS for dynamic vs SLRlDORIS reduced-dynamic orbits and in comparison with orbits produced by other analysis centers (Lemoine et al., 2010; Zelensky et al., 2010; Cerri et al., 2010). We have recently upgraded the GEODYN software to implement model improvements for GPS processing. We describe the implementation of IGS standards to the Jason2 GEODYN GPS processing, and other dynamical and measurement model improvements. Our GPS-only JASON-2 orbit accuracy is assessed using a number of tests including analysis of independent SLR and altimeter crossover residuals, orbit overlap differences, and direct comparison to orbits generated at GSFC using SLR and DORIS tracking, and to orbits generated externally at other centers. Tests based on SLR and the altimeter crossover residuals provide the best performance indicator for independent validation of the NASAlGSFC GPS-only reduced dynamic orbits. For the ITRF2005 and ITRF2008 implementation of our GPS-only obits we are using the IGS05 and IGS08 standards. Reduced dynamic versus dynamic orbit differences are used to characterize the remaining force model error and TRF instability. We evaluate the GPS vs SLR & DORIS orbits produced using the GEODYN software and assess in particular their consistency radially and the stability of the altimeter satellite reference frame in the Z direction for both ITRF2005 and ITRF2008 as a proxy to assess the consistency of the reference frame for altimeter satellite POD.

  3. The Ocean Surface Topography Sentinel-6/Jason-CS Mission (United States)

    Giulicchi, L.; Cullen, R.; Donlon, C.; Vuilleumier@esa int, P.


    The Sentinel-6/Jason-CS mission consists of two identical satellites flying in sequence and designed to provide operational measurements of sea surface height significant wave high and wind speed to support operational oceanography and climate monitoring. The mission will be the latest in a series of ocean surface topography missions that will span nearly three decades. They follow the altimeters on- board TOPEX/Poseidon through to Jason-3 (launched in January 2016). Jason-CS will continue to fulfil objectives of the reference series whilst introducing a major enhancement in capability providing the operational and science oceanographic community with the state of the art in terms of spacecraft, measurement instrumentation design thus securing optimal operational and science data return. As a secondary objective the mission will also include Radio Occultation user services. Each satellite will be launched sequentially into the Jason orbit (up to 66 latitude) respectively in 2020 and 2025. The principle payload instrument is a high precision Ku/C band radar altimeter with retrieval of geophysical parameters (surface elevation, wind speed and SWH) from the altimeter data require supporting measurements: a DORIS receiver for Precise Orbit Determination; The Climate Quality Advanced Microwave Radiometer (AMR-C) for high stability path delay correction. Orbit tracking data are also provided by GPS & LRA. An additional GPS receiver will be dedicated to radio-occultation measurements. The programme is a part of the European Community Copernicus initiative, whose objective is to support Europe's goals regarding sustainable development and global governance of the environment by providing timely and quality data, information, services and knowledge. The Sentinel-6/Jason-CS in particular is a cooperative mission with contributions from NASA, NOAA, EUMETSAT, ESA, CNES and the European Union.

  4. Improvements To Solar Radiation Pressure Modeling For Jason-2 (United States)

    Zelensky, N. P.; Lemoine, F. G.; Melachroinos, S.; Pavlis, D.; Bordyugov, O.


    Jason-2 is the follow-on to the Jason-1 and TOPEX/Poseidon radar altimetry missions observing the sea surface. The computed orbit is used to reference the altimeter measurement to the center of the Earth, and thus the accuracy and stability of the orbit are critical to the sea surface observation accuracy. A 1-cm Jason-2 radial orbit accuracy goal is required for meeting the 2.5 cm altimeter measurement goal. Also mean sea level change estimated from altimetry requires orbit stability to well below 1 mm/yr. Although 1-cm orbits have been achieved, unresolved large draconitic period error signatures remain and are believed to be due to mis-modeling of the solar radiation pressure (SRP) forces acting on the satellite. Such error may easily affect the altimeter data, and can alias into any number of estimated geodetic quantities using Jason-2. Precision orbit determination (POD) at GSFC and other analysis centers employs an 8-panel "macromodel" representation of the satellite geometry and optical properties to model SRP. Telemetered attitude and modeled solar array pitch angles (SAPA) are used to orient the macromodel. Several possible improvements to SRP modeling are evaluated and include: 1) using telemetered SAPA values, 2) using the SRP model developed at UCL for the very similar Jason-1, 3) re-tuning the macromodel, 4) modifying POD strategy to estimate a coefficient of reflectivity (CR) for every arc, or else using the reduced-dynamic approach. Improvements to POD modeling are evaluated through analysis of tracking data residuals, estimated empirical accelerations, and orbit differences.

  5. Emergence of Streptococcus pyogenes emm102 causing toxic shock syndrome in Southern Taiwan during 2005-2012.

    Directory of Open Access Journals (Sweden)

    Jiun-Nong Lin

    Full Text Available BACKGROUND: Streptococcal toxic shock syndrome (STSS is an uncommon but life-threatening disease caused by Streptococcus pyogenes. METHODS: To understand the clinical and molecular characteristics of STSS, we analyzed clinical data and explored the emm types, superantigen genes, and pulsed-field gel electrophoresis of causative S. pyogenes isolates obtained between 2005 and 2012. RESULTS: In total, 53 patients with STSS were included in this study. The median age of the patients was 57 years (range: 9-83 years, and 81.1% were male. The most prevalent underlying disease was diabetes mellitus (45.3%. Skin and soft-tissue infection accounted for 86.8% of STSS. The overall mortality rate was 32.1%. Underlying diseases had no statistical impact on mortality. A total of 19 different emm types were identified. The most prevalent emm type was emm102 (18.9%, followed by emm11 (17%, emm1 (11.3%, emm87 (9.4%, and emm89 (7.5%. There was no statistically significant association between emm type and a fatal outcome. Among the superantigen genes, speB was the most frequently detected one (92.5%, followed by smeZ (90.6%, speG (81.1%, speC (39.6%, and speF (39.6%. The majority of emm102 strains were found to have speB, speC, speG, and smeZ. The presence of speG was negatively associated with a fatal outcome (P = 0.045. CONCLUSIONS: Our surveillance revealed the emergence of uncommon emm types, particularly emm102, causing STSS in southern Taiwan. Characterization of clinical, epidemiological, and molecular characteristics of STSS will improve our understanding of this life-threatening disease.

  6. Complete Genome Sequences of emm111 Type Streptococcus pyogenes Strain GUR, with Antitumor Activity, and Its Derivative Strain GURSA1 with an Inactivated emm Gene

    DEFF Research Database (Denmark)

    Suvorova, Maria A; Tsapieva, Anna N; Bak, Emilie Glad


    We present here the complete genome sequence of Streptococcus pyogenes type emm111 strain GUR, a throat isolate from a scarlet fever patient, which has been used to treat cancer patients in the former Soviet Union. We also present the complete genome sequence of its derivative strain GURSA1...

  7. Calorimetrics on the JASON low power teaching and research reactor

    International Nuclear Information System (INIS)

    Moorman, J.E.


    Teaching and research reactors are often of low power. This low power cannot be measured simply by calorimetrics of the coolant because the fraction of the nuclear power which is not transferred to the coolant is significant. However, the power still needs to be known accurately to support a safety case. This paper presents a simple and novel method whereby the JASON low power reactor was thermally calibrated and the power assessed directly. (author)

  8. An emm5 Group A Streptococcal Outbreak Among Workers in a Factory Manufacturing Telephone Accessories

    Directory of Open Access Journals (Sweden)

    Mingliang Chen


    Full Text Available Ranked among the top10 infectious causes of death worldwide, group A Streptococcus (GAS causes small- and large-scale outbreaks, depending on the trigger as transmission of a GAS strain or expansion of predominant clones. In China, GAS infections other than scarlet fever are not notifiable. In Shanghai, an epidemiological investigation was initiated after two successive severe pneumonia cases with one death in a digital factory, from where outbreaks are less widely reported. The investigation was performed using emm typing, pulsed-field gel electrophoresis (PFGE typing, superantigen profiling, and genome analysis. This enabled characterization of relatedness among the outbreak isolates and identification of the mobile genetic elements present. Among 57 patients with respiratory symptoms investigated in the factory, emm5 GAS strains were isolated from 8 patients. The eight GAS infection cases comprising one fatal severe pneumonia case, six influenza-like illness cases, and one pharyngitis case. Two risk factors were identified: adult with an age of 18–20 years and close contact with a GAS patient or carrier. GAS attack rate was 14.0% (8/57, and GAS carriage rate was probably around 2.7% (14/521 based on surveys in two nearby districts. All the 10 outbreak associated isolates were assigned to emm5 and sequence type ST-99 (emm5/ST-99, harbored superantigen genes speC, speG, and smeZ, and were assigned to two similar PFGE patterns (clones. Among the outbreak associated isolates, all carried ermA with resistance to erythromycin and inducible resistance to clindamycin, and eight (80% carried a tetM gene with resistance to tetracycline. Among the 14 carriage isolates, 12 were emm12/ST-36, and 2 were emm1/ST-28, all with superantigen genes speC, speG, ssa, and smeZ. All the carriage isolates harbored ermB and tetM with resistance to erythromycin, clindamycin, and tetracycline. Genome analysis showed the two outbreak clones were closely related and

  9. Epidemiological study of erythromycin-resistant Streptococcus pyogenes from Korea and Japan by emm genotyping and multilocus sequence typing. (United States)

    Takahashi, Takashi; Arai, Kazuaki; Lee, Dong Hyun; Koh, Eun Ha; Yoshida, Haruno; Yano, Hisakazu; Kaku, Mitsuo; Kim, Sunjoo


    We determined the epidemiological characteristics of erythromycin (EM)-resistant Streptococcus pyogenes (group A streptococci, GAS) strains isolated from Korea and Japan, using emm genotyping and multilocus sequence typing (MLST). Clinical isolates of GAS had been collected from 1992 to 2012 in Korea and from 2004 to 2009 in Japan. EM resistance was determined by the microdilution method, and resistance genotypes were assessed by PCR. The emm genotyping and MLST were performed by DNA sequencing. The emm genotypes and sequence types (STs) were concordant in 143 (85.1%) of 168 EM-resistant GAS strains from Korea. ST36/emm12 (35.1%), ST52/emm28 (22.6%), and ST49/emm75 (16.1%) were the most common types. Most of the ST36 (93.9%) and ST52 (95.8%) strains harbored erm(B), whereas strains ST49, ST42, and ST15 contained mef(A). The concordance between emm genotypes and STs was 41 (93.2%) among 44 EM-resistant GAS strains from Japan. ST36/emm12 (34.1%), ST49/emm75 (18.2%), and ST28/emm1 (15.9%) were the major types. ST36 isolates harbored either erm(B) (56.3%) or mef(A) (37.5%), whereas isolates ST28, ST49, and ST38 carried only mef(A). The proportion of erm(B) and mef(A) was 66.1% and 33.3% in Korea and 22.7% and 68.2% in Japan, respectively. The common STs in Korea and Japan were ST36 and ST49, whereas ST52 was present only in Korea and ST28 only in Japan. Genotype erm(B) was predominant in Korea, whereas mef(A) was frequent in Japan. There were differences between Korea and Japan regarding the frequencies of emm genotypes, STs, and EM resistance genes among the EM-resistant GAS.

  10. EMM ontology on GMOs : customization of MedISys for the monitoring of GMOs without positive safety assessment

    NARCIS (Netherlands)

    Prins, T.W.; Top, J.L.; Kok, E.J.; Marvin, H.J.P.


    The Europe Media Monitor (EMM) is a news gathering engine which is operated by the Joint Research Centre (JRC). EMM analyses news items published on the WWW, extracts relevant information, aggregates the collected information, issues alerts, and produces visual presentations of the information

  11. Measurement and analysis of neutron flux distribution of STACY heterogeneous core by position sensitive proportional counter. Contract research

    CERN Document Server

    Murazaki, M; Uno, Y


    We have measured neutron flux distribution around the core tank of STACY heterogeneous core by position sensitive proportional counter (PSPC) to develop the method to measure reactivity for subcritical systems. The neutron flux distribution data in the position accuracy of +-13 mm have been obtained in the range of uranium concentration of 50g/L to 210g/L both in critical and in subcritical state. The prompt neutron decay constant, alpha, was evaluated from the measurement data of pulsed neutron source experiments. We also calculated distribution of neutron flux and sup 3 He reaction rates at the location of PSPC by using continuous energy Monte Carlo code MCNP. The measurement data was compared with the calculation results. As results of comparison, calculated values agreed generally with measurement data of PSPC with Cd cover in the region above half of solution height, but the difference between calculated value and measurement data was large in the region below half of solution height. On the other hand, ...

  12. Streptococcal toxic shock syndrome caused by the dissemination of an invasive emm3/ST15 strain of Streptococcus pyogenes. (United States)

    Sekizuka, Tsuyoshi; Nai, Emina; Yoshida, Tomohiro; Endo, Shota; Hamajima, Emi; Akiyama, Satoka; Ikuta, Yoji; Obana, Natsuko; Kawaguchi, Takahiro; Hayashi, Kenta; Noda, Masahiro; Sumita, Tomoko; Kokaji, Masayuki; Katori, Tatsuo; Hashino, Masanori; Oba, Kunihiro; Kuroda, Makoto


    Streptococcus pyogenes (group A Streptococcus [GAS]) is a major human pathogen that causes a wide spectrum of clinical manifestations. Although invasive GAS (iGAS) infections are relatively uncommon, emm3/ST15 GAS is a highly virulent, invasive, and pathogenic strain. Global molecular epidemiology analysis has suggested that the frequency of emm3 GAS has been recently increasing. A 14-year-old patient was diagnosed with streptococcal toxic shock syndrome and severe pneumonia, impaired renal function, and rhabdomyolysis. GAS was isolated from a culture of endotracheal aspirates and designated as KS030. Comparative genome analysis suggested that KS030 is classified as emm3 (emm-type) and ST15 (multilocus sequencing typing [MLST]), which is similar to iGAS isolates identified in the UK (2013) and Switzerland (2015). We conclude that the global dissemination of emm3/ST15 GAS strain has the potential to cause invasive disease.

  13. The AORTA Architecture: Integrating Organizational Reasoning in Jason

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt; Dignum, Virginia; Villadsen, Jørgen


    organization-aware. It is designed such that it provides organizational reasoning capabilities to agents implemented in existing agent programming languages without being tied to a specific organizational model. We show how it can be integrated in the Jason agent programming language, and discuss how...... the expected behavior of the agents. Agents need to be able to reason about the regulations, so that they can act within the expected boundaries and work towards the objectives of the organization. In this paper, we describe the AORTA (Adding Organizational Reasoning to Agents) architecture for making agents...... the agents can coordinate their organizational tasks using AORTA....

  14. Evaluation of simplified dna extraction methods for EMM typing of group a streptococci

    Directory of Open Access Journals (Sweden)

    Jose JJM


    Full Text Available Simplified methods of DNA extraction for amplification and sequencing for emm typing of group A streptococci (GAS can save valuable time and cost in resource crunch situations. To evaluate this, we compared two methods of DNA extraction directly from colonies with the standard CDC cell lysate method for emm typing of 50 GAS strains isolated from children with pharyngitis and impetigo. For this, GAS colonies were transferred into two sets of PCR tubes. One set was preheated at 94oC for two minutes in the thermal cycler and cooled while the other set was frozen overnight at -20oC and then thawed before adding the PCR mix. For the cell lysate method, cells were treated with mutanolysin and hyaluronidase before heating at 100oC for 10 minutes and cooling immediately as recommended in the CDC method. All 50 strains could be typed by sequencing the hyper variable region of the emm gene after amplification. The quality of sequences and the emm types identified were also identical. Our study shows that the two simplified DNA extraction methods directly from colonies can conveniently be used for typing a large number of GAS strains easily in relatively short time.

  15. Emergence of scarlet fever Streptococcus pyogenes emm12 clones in Hong Kong is associated with toxin acquisition and multidrug resistance. (United States)

    Davies, Mark R; Holden, Matthew T; Coupland, Paul; Chen, Jonathan H K; Venturini, Carola; Barnett, Timothy C; Zakour, Nouri L Ben; Tse, Herman; Dougan, Gordon; Yuen, Kwok-Yung; Walker, Mark J


    A scarlet fever outbreak began in mainland China and Hong Kong in 2011 (refs. 1-6). Macrolide- and tetracycline-resistant Streptococcus pyogenes emm12 isolates represent the majority of clinical cases. Recently, we identified two mobile genetic elements that were closely associated with emm12 outbreak isolates: the integrative and conjugative element ICE-emm12, encoding genes for tetracycline and macrolide resistance, and prophage ΦHKU.vir, encoding the superantigens SSA and SpeC, as well as the DNase Spd1 (ref. 4). Here we sequenced the genomes of 141 emm12 isolates, including 132 isolated in Hong Kong between 2005 and 2011. We found that the introduction of several ICE-emm12 variants, ΦHKU.vir and a new prophage, ΦHKU.ssa, occurred in three distinct emm12 lineages late in the twentieth century. Acquisition of ssa and transposable elements encoding multidrug resistance genes triggered the expansion of scarlet fever-associated emm12 lineages in Hong Kong. The occurrence of multidrug-resistant ssa-harboring scarlet fever strains should prompt heightened surveillance within China and abroad for the dissemination of these mobile genetic elements.

  16. Prevalence of emm types and antimicrobial susceptibility of Streptococcus dysgalactiae subsp. equisimilis in Austria. (United States)

    Leitner, Eva; Zollner-Schwetz, Ines; Zarfel, Gernot; Masoud-Landgraf, Lilian; Gehrer, Michael; Wagner-Eibel, Ute; Grisold, Andrea J; Feierl, Gebhard


    An increase of severe infections caused by Streptococcus dysgalactiae subsp. equisimilis (SDSE) similar to infections caused by Streptococcus pyogenes has been reported over the last years. Little is known about infections with SDSE in Austria. Therefore, we investigated a collection of 113 SDSE invasive and non-invasive isolates from different infection sites and type of infections as well as patients' characteristics. The isolates were phenotypically identified and emm typed using the enlarged emm database from the Centers for Disease Control and Prevention. Additionally, 13 antimicrobial agents were tested using EUCAST guidelines and virulence genes were investigated. Severe SDSE infections were most common in elderly men with underlying diseases especially diabetes mellitus. With VitekMS identification of SDSE isolates was successful to the species level only. Emm typing revealed 24 different emm types, one new type and one new subtype. StG485, stG6, stC74a, stG643, and stG480 were the predominant types in this study, stC74a and stG652 in invasive infections and stG643, stC74a and stG485 in non-invasive infections. Resistance was observed to tetracycline (62%), macrolides (13%) with one M phenotype, and clindamycin (12%) presenting 6 constitutive MLS(B) phenotypes and 8 inducible MLS(B) phenotypes. Levofloxacin resistance was detected only in one isolate. All isolates tested for virulence genes were positive for scpA, ska, saga and slo. Superantigenic genes were negative except speG(dys) (positive 17/34; 50%). This paper presents the first report of SDSE infections in Austria. Severe SDSE infections were found mainly in elderly men with underlying diseases. SDSE isolates demonstrated substantial emm type diversity without association with infections site or invasiveness. Analysis of virulence genes showed no significant difference between invasive and non-invasive infections. Copyright © 2015 Elsevier GmbH. All rights reserved.

  17. Jason and "The Flaming Hamsters of Death": A Reality Rub Reclaiming Intervention (United States)

    Laursen, Erik K.; Felski-Smith, Cara


    Jason is a 17-year-old high school senior currently classified as a student who is Other Health Impaired due to anxiety, obsessive compulsive disorder, and germ phobia (an intense fear of something that poses little actual threat--but can cause severe anxiety or a full panic attack). He also has a severe learning disability in reading. Jason is…

  18. Ocean Surface Topography Mission (OSTM) /Jason-3 Data Collection, 2015- (NCEI Accession 0118278) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — OSTM/JASON-3 is a follow-on mission continuing the TOPEX/Poseidon and Jason-1/2, and is designed to ensure continuity of high quality measurements for ocean science...

  19. The AORTA Architecture: Integrating Organizational Reasoning in Jason

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt; Dignum, Virginia; Villadsen, Jørgen


    the expected behavior of the agents. Agents need to be able to reason about the regulations, so that they can act within the expected boundaries and work towards the objectives of the organization. In this paper, we describe the AORTA (Adding Organizational Reasoning to Agents) architecture for making agents......Open systems are characterized by a diversity of heterogeneous and autonomous agents that act according to private goals, and with a behavior that is hard to predict. They can be regulated through organizations similar to human organizations, which regulate the agents’ behavior space and describe...... organization-aware. It is designed such that it provides organizational reasoning capabilities to agents implemented in existing agent programming languages without being tied to a specific organizational model. We show how it can be integrated in the Jason agent programming language, and discuss how...

  20. A grid-independent EMMS/bubbling drag model for bubbling and turbulent fluidization

    DEFF Research Database (Denmark)

    Luo, Hao; Lu, Bona; Zhang, Jingyuan


    The EMMS/bubbling drag model takes the effects of meso-scale structures (i.e. bubbles) into modeling of drag coefficient and thus improves coarse-grid simulation of bubbling and turbulent fluidized beds. However, its dependence on grid size has not been fully investigated. In this article, we adopt...... a periodic domain show the new drag model is less sensitive to grid size because of the additional dependence on local slip velocity. When applying the new drag model to simulations of realistic bubbling and turbulent fluidized beds, we find grid-independent results are easier to obtain for high......-velocity turbulent fluidized bed cases. The simulation results indicate that the extended EMMS/bubbling drag model is a potential method for coarse-grid simulations of large-scale fluidized beds....

  1. The impact of using jason-1 and cryosat-2 geodetic mission altimetry for gravity field modeling

    DEFF Research Database (Denmark)

    Andersen, Ole Baltazar; Jain, Maulik; Knudsen, Per


    operating in a geodetic mission as part its end of life mission. In this presentation, we perform an investigation of the impact of the Cryosat-2 and Jason-1 geodetic missions on high resolution marine gravity field mapping through comparison with recent high quality marine gravity measured by the United...... States Naval Ship Bowditch in the Western Pacific Ocean in 2006. Comparisons of pre and post Cryosat- 2/Jason-1 gravity fields illustrated the importance of these new geodetic missions for altimeter marine gravity field mapping. Altimetric gravity derived using 1 year of either Cryosat-2 or Jason-1...

  2. The JASON reactor at the Royal Naval College: Silver Jubilee 6th November 1987

    International Nuclear Information System (INIS)

    Lakey, J.R.A.; Roust, C.B.


    The 10 kW Research and Training Reactor Jason has been used at the Royal Naval College for 25 years in support of the Naval Nuclear Submarine Propulsion Programme. The principal features of Jason, relevant to its training role are given, along with the specifications of Jason, instrumentation, maintenance and operational experience. The educational role of the reactor is described with respect to the Nuclear Reactor Course, Nuclear Advanced Course, and the Nuclear Radiation Protection Course. Future developments in operator training, advantages of the low power reactor, quality control of education and training, and research and development, are also discussed. (U.K.)

  3. Ocean Surface Topography Mission (OSTM) /Jason-2: Auxiliary Files (NODC Accession 0044983) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains the data descriptions for the OSTM/Jason-2 Auxiliary data files, which is served through the NOAA/NESDIS Comprehensive Large Array-data...

  4. Ocean Surface Topography Mission (OSTM) /Jason-2: Orbital Information (NODC Accession 0044985) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains the descriptions for the OSTM/Jason-2 orbital information, which is served through the NOAA/NESDIS Comprehensive Large Array-data Stewardship...

  5. The Jasons: The Secret History of Science's Postwar Elite

    Energy Technology Data Exchange (ETDEWEB)

    Finkbeiner, Ann (Johns Hopkins University)


    This book is a history/profile of the group, called Jason, of academic scientists who advise the government. The book starts where the Manhattan Project ends -- with physicists trying to decide, having let the genie out of the bottle, how to get it back in again. One result of their attempts was Jason. Jason is 30 to 50 scientists who meet for six weeks every summer to answer questions for the government -- usually for the defense department or the intelligence community -- about national security issues. They specialize in studies for the Department of Energy on the technical backing for treaties to ban the bomb. Jason is unique, not only in this country, but in the world. The book is about the group's attempts to hold onto their scientific souls, remain independent, and still stay in business.

  6. Ocean Surface Topography Mission (OSTM) /Jason-3: Auxiliary Files, 2015- (NODC Accession 0122597) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Jason-3 is the fourth mission in U.S.-European series of satellite missions that measure the height of the ocean surface. Scheduled to launch in 2015, the mission...

  7. Ocean Surface Topography Mission (OSTM) /Jason-3: Orbital Information, 2015- (NODC Accession 0122598) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Jason-3 is the fourth mission in U.S.-European series of satellite missions that measure the height of the ocean surface. Scheduled to launch in 2015, the mission...

  8. Ocean Surface Topography Mission (OSTM) /Jason-3: Ancillary Files, 2015- (NCEI Accession 0122596) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Jason-3 is the fourth mission in U.S.-European series of satellite missions that measure the height of the ocean surface. Scheduled to launch in 2015, the mission...

  9. Ocean Surface Topography Mission (OSTM) /Jason-3: Telemetry, 2015- (NODC Accession 0122599) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Jason-3 is the fourth mission in U.S.-European series of satellite missions that measure the height of the ocean surface. Scheduled to launch in 2015, the mission...

  10. Ocean Surface Topography Mission (OSTM) /Jason-2: Ancillary Files (NODC Accession 0044982) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains the data descriptions for the OSTM/Jason-2 Ancillary data files, which is served through the NOAA/NESDIS Comprehensive Large Array-data...

  11. Ocean Surface Topography Mission (OSTM) /Jason-2: Telemetry (NODC Accession 0044986) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains the data descriptions for the OSTM/Jason-2 Telemetry data, which is served through the NOAA/NESDIS Comprehensive Large Array-data Stewardship...

  12. Streptococcus pyogenes emm types and subtypes of isolates from paediatric asymptomatic carriers and children with pharyngitis. (United States)

    Blandino, Giovanna; Puglisi, Salvatore; Speciale, Annamaria; Musumeci, Rosario


    This study determined emm subtypes of Streptococcus pyogenes strains isolated from asymptomatic carriers and children with pharyngitis. All strains were previously investigated for fibronectin-binding genes (prtF1 and prtF2) and antimicrobial susceptibility. The most significant differences between the two groups, which share only 5 of the 14 detected emmsubtypes, concern the presence of the two more common emmsubtypes, 12.0 (50.0% vs. 3.1%, for asymptomatic carriers and children with pharyngitis, respectively) and 1.0 (28.1% vs. 0%, for children with pharyngitis and asymptomatic carriers, respectively).

  13. Comparative epidemiology of Streptococcus pyogenes emm-types causing invasive and noninvasive infections in French children by use of high-resolution melting-polymerase chain reaction. (United States)

    d'Humières, Camille; Bidet, Philippe; Levy, Corinne; Béchet, Stéphane; Bonacorsi, Stéphane; Bingen, Edouard; Cohen, Robert


    This study aims to analyze the epidemiology of Group A streptococci (GAS) emm-types causing invasive and noninvasive infections in French children. From September 2009 to May 2011, we analyzed GAS isolates from 585 pharyngitis, 125 invasive infections and, for the first time in France, 32 healthy carriers. M protein gene (emm) typing of the isolates was carried out by a new rapid technique, combining 3 multiplex-polymerase chain reactions (PCRs) coupled to high-resolution melting (HRM) curves, able to detect 13 major emm-types (emm 1, 3, 4, 6, 11, 12, 22, 28, 75, 77, 87, 89 and 102). GAS belonging to emm-type 1 were more frequently found among invasive infections than among pharyngitis (24.0% vs. 11.5%, P type 4, 17.4% vs. 6.4%, P = 0.002 and emm-type 89, 9.9% vs. 2.4%, P = 0.006, respectively) and emm 3 and 4 were more common in cases of pharyngitis associated with scarlet fever (21.6% vs. 6.0%, P epidemiological studies. Comparison of GAS causing invasive and noninvasive infections in the same population of children displays an unbalanced repartition of emm-types.

  14. JASON-1 Precise Orbit Determination (POD)with SLR and DORIS Tracking (United States)

    Zelensky, N. P.; Luthcke, S. B.; Rowlands, D. D.; Beckley, B. D.; Lemoine, Frank G.; Wang, Y. M.; Chinn, D. S.; Williams, T. A.


    Jason-1, the TOPEX/POSEIDON (T/P) radar altimeter follow-on, is intended to continue measurement of the ocean surface with the same, if not better accuracy. T/P has demonstrated that, the time variation of ocean topography can be determined with an accuracy of a few centimeters, thanks to the availability of highly accurate orbits based on SLR and DORIS tracking. For verification and cross-calibration, Jason-1, was initially injected into the T/P orbit, flying just 72 seconds ahead of T/P. This configuration lasted over 21 Jason cycles. In mid-August T/P was maneuvered into its final tandem configuration, a parallel groundtrack, in order to improve the combined coverage. Preliminary investigations using cycles 1-9, shown at the June 2002 SWT, indicated that nominal Jason orbits can achieve the 2-3 cm accuracy objective, however several puzzling aspects of SLR and DORIS measurement modeling were also observed. This paper presents recent analysis of Jason SLR+DORIS POD spanning more than 20 cycles, and revisits several of the more puzzling issues, including estimation of the Laser Retroreflector Array (LRA) offset. The accuracy of the orbits and of the measurement modeling are evaluated using several tests, including SLR, DORIS, and altimeter crossover residual analysis, altimeter collinear analysis, and direct comparison with GPS and other orbits. T/P POD results over the same period are used as a reference.

  15. CAWRES: A Waveform Retracking Fuzzy Expert System for Optimizing Coastal Sea Levels from Jason-1 and Jason-2 Satellite Altimetry Data

    Directory of Open Access Journals (Sweden)

    Nurul Hazrina Idris


    Full Text Available This paper presents the Coastal Altimetry Waveform Retracking Expert System (CAWRES, a novel method to optimise the Jason satellite altimetric sea levels from multiple retracking solutions. CAWRES’ aim is to achieve the highest possible accuracy of coastal sea levels, thus bringing measurement of radar altimetry data closer to the coast. The principles of CAWRES are twofold. The first is to reprocess altimeter waveforms using the optimal retracker, which is sought based on the analysis from a fuzzy expert system. The second is to minimise the relative offset in the retrieved sea levels caused by switching from one retracker to another using a neural network. The innovative system is validated against geoid height and tide gauges in the Great Barrier Reef, Australia for Jason-1 and Jason-2 satellite missions. The regional investigations have demonstrated that the CAWRES can effectively enhance the quality of 20 Hz sea level data and recover up to 16% more data than the standard MLE4 retracker over the tested region. Comparison against tide gauge indicates that the CAWRES sea levels are more reliable than those of Sensor Geophysical Data Records (SGDR products, because the former has a higher (≥0.77 temporal correlation and smaller (≤19 cm root mean square errors. The results demonstrate that the CAWRES can be applied to coastal regions elsewhere as well as other satellite altimeter missions.

  16. Trading Capsule for Increased Cytotoxin Production: Contribution to Virulence of a Newly Emerged Clade of emm89 Streptococcus pyogenes. (United States)

    Zhu, Luchang; Olsen, Randall J; Nasser, Waleed; de la Riva Morales, Ivan; Musser, James M


    Strains of emm89 Streptococcus pyogenes have become one of the major causes of invasive infections worldwide in the last 10 years. We recently sequenced the genome of 1,125 emm89 strains and identified three major phylogenetic groups, designated clade 1, clade 2, and the epidemic clade 3. Epidemic clade 3 strains, which now cause the great majority of infections, have two distinct genetic features compared to clade 1 and clade 2 strains. First, all clade 3 organisms have a variant 3 nga promoter region pattern, which is associated with increased production of secreted cytolytic toxins SPN (S. pyogenes NADase) and SLO (streptolysin O). Second, all clade 3 strains lack the hasABC locus mediating hyaluronic acid capsule synthesis, whereas this locus is intact in clade 1 and clade 2 strains. We constructed isogenic mutant strains that produce different levels of SPN and SLO toxins and capsule (none, low, or high). Here we report that emm89 strains with elevated toxin production are significantly more virulent than low-toxin producers. Importantly, we also show that capsule production is dispensable for virulence in strains that already produce high levels of SPN and SLO. Our results provide new understanding about the molecular mechanisms contributing to the rapid emergence and molecular pathogenesis of epidemic clade 3 emm89 S. pyogenes. S. pyogenes (group A streptococcus [GAS]) causes pharyngitis ("strep throat"), necrotizing fasciitis, and other human infections. Serious infections caused by emm89 S. pyogenes strains have recently increased in frequency in many countries. Based on whole-genome sequence analysis of 1,125 strains recovered from patients on two continents, we discovered that a new emm89 clone, termed clade 3, has two distinct genetic features compared to its predecessors: (i) absence of the genes encoding antiphagocytic hyaluronic acid capsule virulence factor and (ii) increased production of the secreted cytolytic toxins SPN and SLO. emm89 S

  17. Preliminary analyses of critical experiments using 10% enriched uranium nitrate solution with the 800mm-diameter cylindrical tank of STACY

    Energy Technology Data Exchange (ETDEWEB)

    Sono, Hiroki; Miyoshi, Yoshinori; Ohno, Akio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment


    STACY, the static experiment critical facility in NUCEF, has the plan of a series of critical experiments using 10% enriched uranium nitrate solution with the 800mm-diameter cylindrical tank. The main purpose of these experiments is to measure the critical solution height and the temperature coefficient of reactivity by varying concentration of uranium and temperature of the fuel solution. Prior to these experiments, it is needed to make a diluting program of the solution, which is utilized to adjust the concentration of uranium, and to estimate the reactivity effect caused by temperature change. Therefore, such neutronic characteristics as critical solution height, height differential reactivity and kinetics parameters, were calculated with computational codes. In these preliminary analyses, simplified formulas to evaluate the above neutronic characteristics were also obtained by the least squares method applied to the results of computations. These formula well agree with computations within 0.1% up to 3.5%, so that they are useful to make detailed plans for the experiments and the reactor operation. Then, the temperature coefficient of reactivity is estimated at 3.85cent/degC, approximately. (author)

  18. A propósito de “feminismos transcorpóreos e o espaço ético da natureza”, de Stacy Alaimo

    Directory of Open Access Journals (Sweden)

    Izabel Brandão


    Full Text Available Conheci o texto de Stacy Alaimo no início do século 21, quando me preparava para um intercâmbio com um colega pesquisador inglês, o ecocrítico Terry Gifford, da University of Leeds, que, já nos anos 1990, havia me apresentado o referencial dos debates relativos à natureza em suas relações com a literatura, quando ambos fazíamos nossos doutorados nas Universidades de Sheffield (eu e de Lancaster (ele, na Inglaterra. O intercâmbio acabou não se materializando devido à crise do governo FHC, que cortou o que podia de bolsas para o exterior. A referência aos estudos ecocríticos permaneceu e procurei estabelecer uma conexão com as questões feministas porque foi sempre nessa seara que procurei ancorar meu pensamento crítico, tanto no âmbito pessoal quanto acadêmico.

  19. Recensão a: Migrating Music, editado por Jason Toynbee and Byron Dueck (2011)


    Vanspauwen, Bart


    UID/EAT/00472/2013 SFRH/BD/92040/2012 Jason Toynbee and Byron Dueck (eds): Migrating Music. London and New York, Routledge, 2011. 256 pp. ISBN 978-0-415-59448-6 Reseña de Bart Paul Vanspauwen (INET-MD, Universidade Nova de Lisboa) publishersversion published

  20. M-protein gene-type distribution and hyaluronic acid capsule in group A Streptococcus clinical isolates in Chile: association of emm gene markers with csrR alleles. (United States)

    Wozniak, A; Rojas, P; Rodríguez, C; Undabarrena, A; Garate, C; Riedel, I; Román, J C; Kalergis, A M; García, P


    Streptococcus pyogenes causes a variety of infections because of virulence factors such as capsular hyaluronic acid and M protein. The aim of this study was to determine emm types and capsule phenotype in 110 isolates of S. pyogenes from patients with invasive (sterile sites) and non-invasive (mainly pharyngitis) infections in Chile, and the relationship between both virulence factors. The most abundant types found were emm12, emm1, emm4 and emm28 and their distribution was similar to that seen in Latin America and developed countries, but very different from that in Asia and Pacific Island countries. Ten of 16 emm types identified in pharyngeal isolates were found in sterile-site isolates, and three of nine emm types of sterile-site isolates occurred in pharyngeal isolates; three emm subtypes were novel. The amount of hyaluronic acid was significantly higher in sterile-site isolates but did not differ substantially among emm types. Only three isolates were markedly capsulate and two of them had mutations in the csrR gene that codes for a repressor of capsule synthesis genes. We found a non-random association between emm types and csrR gene alleles suggesting that horizontal gene transfer is not freely occurring in the population.

  1. Outbreak of Invasive Infections From Subtype emm26.3 Group A Streptococcus Among Homeless Adults-Anchorage, Alaska, 2016-2017. (United States)

    Mosites, Emily; Frick, Anna; Gounder, Prabhu; Castrodale, Louisa; Li, Yuan; Rudolph, Karen; Hurlburt, Debby; Lecy, Kristen D; Zulz, Tammy; Adebanjo, Tolu; Onukwube, Jennifer; Beall, Bernard; Van Beneden, Chris A; Hennessy, Thomas; McLaughlin, Joseph; Bruce, Michael G


    In 2016, we detected an outbreak of group A Streptococcus (GAS) invasive infections among the estimated 1000 persons experiencing homelessness (PEH) in Anchorage, Alaska. We characterized the outbreak and implemented a mass antibiotic intervention at homeless service facilities. We identified cases through the Alaska GAS laboratory-based surveillance system. We conducted emm typing, antimicrobial susceptibility testing, and whole-genome sequencing on all invasive isolates and compared medical record data of patients infected with emm26.3 and other emm types. In February 2017, we offered PEH at 6 facilities in Anchorage a single dose of 1 g of azithromycin. We collected oropharyngeal and nonintact skin swabs on a subset of participants concurrent with the intervention and 4 weeks afterward. From July 2016 through April 2017, we detected 42 invasive emm26.3 cases in Anchorage, 35 of which were in PEH. The emm26.3 isolates differed on average by only 2 single-nucleotide polymorphisms. Compared to other emm types, infection with emm26.3 was associated with cellulitis (odds ratio [OR], 2.5; P = .04) and necrotizing fasciitis (OR, 4.4; P = .02). We dispensed antibiotics to 391 PEH. Colonization with emm26.3 decreased from 4% of 277 at baseline to 1% of 287 at follow-up (P = .05). Invasive GAS incidence decreased from 1.5 cases per 1000 PEH/week in the 6 weeks prior to the intervention to 0.2 cases per 1000 PEH/week in the 6 weeks after (P = .01). In an invasive GAS outbreak in PEH in Anchorage, mass antibiotic administration was temporally associated with reduced invasive disease cases and colonization prevalence.

  2. Continuous Monitoring of the Jason-l and TOPEX/POSEIDON Ocean Altimetry Missions from Dedicated Calibration Sites (United States)

    Haines, Bruce; Bonnefond, Pascal; Watson, Christopher; Born, George; Coleman, Richard; Exertier, Pierre; Gill, Stephen; Jan, Gwenaele; Jeansou, Eric; Laurain, Olivier; hide


    We present calibration results from Jason-1 and TOPEX/POSEIDON overflights of the three dedicated verification sites: 1) a California offshore oil platform (Harvest); 2) the Mediterranean island of Corsica (Cape Senetosa), and 3) the Bass Strait off the coast of Tasmania. The high-accuracy of the Jason-1 measurement system is evident in the results from the dedicated calibration experiments. These experiments do indicate, however, that the Jason-1 sea-surface-height (SSH) measurements are biased high by approximately 12-15 cm. We discuss the implications of geographically correlated errors on the determination of the SSH bias.

  3. A robust and stable PLC based control system for 40kJ/25kV EMM system

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, Vijay; Saroj, P.C.; Kulkarni, M.R.; Kumar, Satendra, E-mail: [Accelerator and Pulse Power Division, Bhabha Atomic Research Centre, Mumbai (India)


    This paper describes the PLC based control system developed for a 40kJ/25kV Electro-magnetic machining (EMM) system. In EMM system large capacitor banks is charged with high voltage to store large energy and the banks is made to discharge into a coil within few milli-seconds using a triggered spark gaps. During discharge of the capacitor large surges and transients are generated in the system. The control system monitors/controls and interlocks all the units of the system for proper operation. The control system is the only subsystem which is electrically connected to all the low and high voltage subsystems. Care should be taken at the signal interfacing with the control system to protect the control system. (author)

  4. Inference of Antibiotic Resistance and Virulence Among Diverse Group A Streptococcus Strains Using emm Sequencing and Multilocus Genotyping Methods (United States)


    Surveillance Center, Silver Spring, Maryland, United States of America Abstract Background: Group A Streptococcus pyogenes (GAS) exhibits a Introduction Group A Streptococcus pyogenes (GAS) is a common agent of pharyngitis, febrile respiratory infection, and...Spratt BG, Kalia A, Cross JH, Bessen DE (2001) Multilocus sequence typing of Streptococcus pyogenes and the relationship between emm type and clone. Infect

  5. A case of descending mediastinitis caused by Streptococcus pyogenes harboring genotype emm25 and sequence type 660. (United States)

    Ohya, Hiroaki; Mori, Nobuaki; Hayashi, Tetsuro; Minami, Shujiro; Higuchi, Akiko; Takahashi, Takashi


    Descending mediastinitis caused by Streptococcus pyogenes (group A streptococcus, GAS) is rare among cases of invasive GAS infection. In this report, we describe a case of a cervical abscess and secondary descending mediastinitis in a previously healthy 39-year-old Japanese man. The patient presented with a 2-week history of a sore throat, and subsequently developed an abscess and descending mediastinitis. We treated the cervical abscess using ampicillin/sulbactam and drainage, and GAS was subsequently isolated in two blood cultures from the patient's admission. Microbiological analyses revealed that the isolate harbored genotype emm25 and sequence type (ST) 660. This strain was susceptible to erythromycin (minimum inhibitory concentration [MIC]: ≤0.12 μg/mL), resistant to minocycline (MIC: >4 μg/mL), and possessed the tet(M) determinant. Although we have reviewed the literature regarding the clinical and microbiological characteristics of descending mediastinitis cause by GAS, little is known regarding epidemiological and clinical characteristics of emm25/ST660 GAS. Furthermore, to best of our knowledge, this is the first reported case of descending mediastinitis caused by emm25/ST660 GAS. Therefore, physicians should be aware of case with a cervical abscess and secondary descending mediastinitis caused by GAS infection, even if the patient is immunocompetent. Copyright © 2017 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  6. EMM-23: a stable high-silica multidimensional zeolite with extra-large trilobe-shaped channels. (United States)

    Willhammar, Tom; Burton, Allen W; Yun, Yifeng; Sun, Junliang; Afeworki, Mobae; Strohmaier, Karl G; Vroman, Hilda; Zou, Xiaodong


    Stable, multidimensional, and extra-large pore zeolites are desirable by industry for catalysis and separation of bulky molecules. Here we report EMM-23, the first stable, three-dimensional extra-large pore aluminosilicate zeolite. The structure of EMM-23 was determined from submicron-sized crystals by combining electron crystallography, solid-state nuclear magnetic resonance (NMR), and powder X-ray diffraction. The framework contains highly unusual trilobe-shaped pores that are bound by 21-24 tetrahedral atoms. These extra-large pores are intersected perpendicularly by a two-dimensional 10-ring channel system. Unlike most ideal zeolite frameworks that have tetrahedral sites with four next-nearest tetrahedral neighbors (Q(4) species), this unusual zeolite possesses a high density of Q(2) and Q(3) silicon species. It is the first zeolite prepared directly with Q(2) species that are intrinsic to the framework. EMM-23 is stable after calcination at 540 °C. The formation of this highly interrupted structure is facilitated by the high density of extra framework positive charge introduced by the dicationic structure directing agent.

  7. Evaluation of Ocean Tide Models Used for Jason-2 Altimetry Corrections

    DEFF Research Database (Denmark)

    Fok, H.S.; Baki Iz, H.; Shum, C. K.


    It has been more than a decade since the last comprehensive accuracy assessment of global ocean tide models. Here, we conduct an evaluation of the barotropic ocean tide corrections, which were computed using FES2004 and GOT00.2, and other models on the Jason-2 altimetry Geophysical Data Record (GDR......), with a focus on selected coastal regions with energetic ocean dynamics. We compared nine historical and contemporary ocean tide models with pelagic tidal constants and with multiple satellite altimetry mission (T/P, ERS-1/-2, Envisat, GFO, Jason-1/-2) sea level anomalies using variance reduction studies.......All accuracy assessment methods show consistent results.We conclude that all the contemporary ocean tide models evaluated have similar performance in the selected coastal regions. However, their accuracies are region-dependent and overall are significantly worse than those in the deep-ocean, which are at the 2...

  8. Jason-1 precision orbit determination using GPS combined with SLR and DORIS tracking data (United States)

    Choi, Key-Rok

    Jason-1, a follow-on altimeter mission to the TOPEX/POSEIDON (T/P) mission, carries receivers for DORIS (Doppler Orbitography and Radiopositioning Integrated by Satellite), SLR (Satellite Laser Ranging) and GPS (Global Positioning System) in support of the Precision Orbit Determination (POD) function. The radial orbit accuracy of the Jason-1 is expected to be 2 cm RMS or better in dynamic approach, with the objective of achieving an accuracy of 1 cm RMS through the improved dynamic models and measurement models. This will require significant improvement in current knowledge of surface force effects as well as improvement in knowledge of gravity field model. Jason-1 orbits were computed with various combinations of three different types of tracking data to investigate the contribution of each tracking system to the accuracy of orbits. The GPS tracking data were analyzed and utilized for POD with the DORIS and SLR tracking data using a dynamical approach. Parameterization related to empirical acceleration and antenna phase center was studied, and optimal relative weighting for each tracking system was examined. The effect of ground station selection on the orbit accuracy was also studied and a method of an optimal network selection was developed. The orbit quality tests were performed through the analysis of tracking residuals, SLR residuals with high-elevation passes, orbit overlap comparisons, and altimeter crossover analysis. The study showed that the contribution of GPS tracking is significant to the improvement of orbit accuracy, especially when GPS tracking is supported by SLR tracking. The SLR residual RMS test, which is an independent and absolute measure of the radial orbit error, clearly indicates that we are approaching the 1-cm radial orbit accuracy for Jason-1.

  9. Jason-3 Level-2 Operational, Interim and Final Geophysical Data Records (X-GDR), 2016 to present (NCEI Accession 0122595) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Jason-3 is the fourth mission in U.S.-European series of satellite missions that measure the height of the ocean surface. Scheduled to launch in 2015, the mission...

  10. Ocean Surface Topography Mission (OSTM) /Jason-2: Near Real-Time Altimetry Validation System (NRTAVS) QA Reports (NODC Accession 0044984) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains the descriptions for the OSTM/Jason-2 Near Real-Time Altimetry Validation System Quality Reports, which are served through the NOAA/NESDIS...

  11. Application of Jason-2/3 Altimetry for Virtual Gauging and Flood Forecasting in Mekong Basin (United States)

    Lee, H.; Hossain, F.; Okeowo, M. A.; Nguyen, L. D.; Bui, D. D.; Chang, C. H.


    Vietnam suffers from both flood and drought during the rainy and dry seasons, respectively, due to its highly varying surface water resources. However, the National Center for Water Resources Planning and Investigation (NAWAPI) states that only 7 surface water monitoring stations have been constructed in Central and Highland Central regions with 100 station planned to be constructed by 2030 throughout Vietnam. For the Mekong Delta (MD), the Mekong River Commission (MRC) provides 7-day river level forecasting, but only at the two gauge stations located near the border between Cambodia and Vietnam ( In order to help stakeholder agencies monitor upstream processes in the rivers and manage their impacts on the agricultural sector and densely populated delta cities, we, first of all, construct the so-called virtual stations throughout the entire Mekong River using the fully automated river level extraction tool with Jason-2/3 Geophysical Research Record (GDR) data. Then, we discuss the potentials and challenges of river level forecasting using Jason-2/3 Interim GDR (IGDR) data, which has 1 - 2 days of latency, over the Mekong River. Finally, based on our analyses, we propose a forecasting system for the Mekong River by drawing from our experience in operationalizing Jason-2 altimetry for Bangladesh flood forecasting.

  12. Evaluation of Coastal Sea Level from Jason-2 Altimetry Offshore Hong Kong (United States)

    Birol, F.; Xu, X. Y., , Dr; Cazenave, A. A.


    In the recent years, several coastal altimetry products of Jason-2 mission have been distributed by different agencies, the most advance ones of which are XTRACK, PISTACH and ALES. Each product represents extraordinary endeavors on some aspects of retracking or advanced geophysical corrections, and each has its advantage. The motivation of this presentation is to evaluate these products in order to refine the sea level measurements at the coast. Three retrackers: MLE4, MLE3 and ALES are focused on. Within 20km coastward, neither GDR nor ALES readily provides sea level anomaly (SLA) measurements, so we recomputed the 20Hz GDR and ALES SLA from the raw data, adopting auxiliary information (such as waveform classification and wet tropospheric delay) from PISTACH. The region of interest is track #153 of the Jason-2 satellite (offshore Hong Kong, China), and the altimetry products are processed over seven years (2008-2015, cycles 1-252). The coastline offshore Hong Kong is rather complicated and we feel that it can be a good indicator of the performance of coastal altimetry under undesirable coast conditions. We computed the bias and noise level of ALES, MLE3 and MLE4 SLA over open ocean and in the coastal zone (within 10km or 5km coast-ward). The results showed that, after outlier-editing, ALES performs better than MLE4 and MLE3 both in terms of noise level and uncertainty in sea level trend estimation. We validated the coastal altimetry-based SLA by comparing with data from the Hong Kong tide gauge (located 10km across-track). An interesting , but still preliminary, result is that the computed sea level trend within 5 km from the coast is significantly larger than the trend estimated at larger distances from the coast. Keywords: Jason-2, Hong Kong coast, ALES, MLE3, MLE4

  13. Multi-technique combination of space geodesy observations: Impact of the Jason-2 satellite on the GPS satellite orbits estimation (United States)

    Zoulida, Myriam; Pollet, Arnaud; Coulot, David; Perosanz, Félix; Loyer, Sylvain; Biancale, Richard; Rebischung, Paul


    In order to improve the Precise Orbit Determination (POD) of the GPS constellation and the Jason-2 Low Earth Orbiter (LEO), we carry out a simultaneous estimation of GPS satellite orbits along with Jason-2 orbits, using GINS software. Along with GPS station observations, we use Jason-2 GPS, SLR and DORIS observations, over a data span of 6 months (28/05/2011-03/12/2011). We use the Geophysical Data Records-D (GDR-D) orbit estimation standards for the Jason-2 satellite. A GPS-only solution is computed as well, where only the GPS station observations are used. It appears that adding the LEO GPS observations results in an increase of about 0.7% of ambiguities fixed, with respect to the GPS-only solution. The resulting GPS orbits from both solutions are of equivalent quality, agreeing with each other at about 7 mm on Root Mean Square (RMS). Comparisons of the resulting GPS orbits to the International GNSS Service (IGS) final orbits show the same level of agreement for both the GPS-only orbits, at 1.38 cm in RMS, and the GPS + Jason2 orbits at 1.33 cm in RMS. We also compare the resulting Jason-2 orbits with the 3-technique Segment Sol multi-missions d'ALTimétrie, d'orbitographie et de localisation précise (SSALTO) POD products. The orbits show good agreement, with 2.02 cm of orbit differences global RMS, and 0.98 cm of orbit differences RMS on the radial component.

  14. Emergence of high-level fluoroquinolone resistance in emm6 Streptococcus pyogenes and in vitro resistance selection with ciprofloxacin, levofloxacin and moxifloxacin. (United States)

    Malhotra-Kumar, Surbhi; Van Heirstraeten, Liesbet; Lammens, Christine; Chapelle, Sabine; Goossens, Herman


    To investigate the prevalence of fluoroquinolone resistance in Streptococcus pyogenes and its in vitro selection by ciprofloxacin and the respiratory fluoroquinolones, levofloxacin and moxifloxacin. S. pyogenes (n = 5851) recovered from pharyngitis and invasive infections during 2003-06 in Belgium were screened for fluoroquinolone non-susceptibility (ciprofloxacin MIC > or =2 mg/L) and further studied for mutations in the topoisomerase genes, reserpine-sensitive efflux, clonality by PFGE and emm typing. Fourteen well-characterized fluoroquinolone-non-susceptible or -susceptible isolates were exposed stepwise to increasing levels of ciprofloxacin, levofloxacin and moxifloxacin. Selected mutants with increased MICs were analysed for resistance mechanisms. Mutation frequencies at 2x and 4x MIC of moxifloxacin and levofloxacin were estimated for a clinical emm6 parent strain carrying mutations in both parC and gyrA. Prevalence of fluoroquinolone-non-susceptible S. pyogenes (n = 437; 7.47%) increased significantly from 2.08% and 5.08% to 13.11% during 2003-05 and decreased to 8.93% in 2006 (chi(2) test; P fluoroquinolone-non-susceptible isolates. Of the 71 S. pyogenes sequenced, 70 harboured first-step parC or gyrA mutations correlating with ciprofloxacin MICs 2-8 mg/L. Reserpine-sensitive efflux was not observed. One emm6parC mutant (Ser79Ala) also showed a second-step mutation in gyrA (Ser81Tyr), with MICs of ciprofloxacin, levofloxacin and moxifloxacin of 32, 8 and 1 mg/L, respectively. Mean mutation frequencies under moxifloxacin selection were 500- to 30 000-fold higher for this strain than those for an emm6 control strain. Selection of the emm6 double mutant with moxifloxacin generated a mutant with a moxifloxacin MIC of 64 mg/L and a levofloxacin MIC of 128 mg/L, and an additional Asp83Tyr substitution in ParC. We report an emergence of levofloxacin and high-level ciprofloxacin resistance associated with a second-step gyrA mutation in a clinical emm6 S. pyogenes


    Directory of Open Access Journals (Sweden)

    Nur Rahman


    Full Text Available Kenaikan muka air laut (Sea Level Rise disebabkan oleh semakin meningkatnya suhu global bumi atau yang biasa disebut dengan pemanasan global. Fenomena ini harus diwaspadai, mengingat luas perairan di Indonesia mendominasi sebesar 75,32 % serta banyak terdapat pemukiman maupun pusat perekonomian yang terletak dekat dengan perairan. Dengan luas perairan yang sangat besar maka metode pengamatan konvensional seperti menggunakan kapal survei kelautan bukanlah metode yang efektif dan efisien. Penggunaan teknologi satelit altimetri menjadi salah satu alternatif yang tepat untuk mengamati fenomena ini. Salah satu satelit altimetri tersebut adalah Satelit Jason-2. Pemantauan kenaikan muka air laut dilakukan pada perairan Indonesia dalam kurun waktu 4 tahun (2009-2012 dengan mengambil 20 titik pengamatan. Terdapat 12 titik yang mengalami kenaikan dengan kenaikan terbesar mencapai 12 mm/tahun yaitu di titik Samudera Pasifik tepatnya sebelah utara Papua Barat, sedangkan kenaikan muka air laut terkecil terjadi pada titik Selat Makassar dengan kenaikan sebesar 0,587 mm/tahun.

  16. Local Marine Geoid Variations and Jason-2 Bias Determination using the Gavdos Permanent Cal/Val Facility

    DEFF Research Database (Denmark)

    Mertikas, S. P.; Daskalakis, A.; Tziavos, I. N.


    , but others are related to under-sampling of the Earth's gravity field due to the resolution of the geoid model. New reference surfaces for calibration have thus emerged. Finally, new updated values for the Jason-2 altimeter bias have been determined as 191.81 ± 2.80 mm with the geoid model and as 181.51 ± 2...

  17. Estimating discharge from the Godavari river using ENVISAT, Jason-2, and SARAL/AltiKa radar altimeters

    Digital Repository Service at National Institute of Oceanography (India)

    Sridevi, T.; Sharma, Rashmi; Mehra, P.; Prasad, K.V.S.R

    were used to construct rating curves. This technique was applied to the ENVISAT (2002–2010), SARAL (2013–2014) derived river heights at Yanam and ENVISAT (2002–2010), SARAL (2013–2014), Jason-2 (2008–2014) derived river heights at Bhadrachalam. A...

  18. Ensemble assimilation of JASON/ENVISAT and JASON/AltiKA altimetric observations with stochastic parameterization of the model dynamical uncertainties (United States)

    Brasseur, Pierre; Candille, Guillem; Bouttier, Pierre-Antoine; Brankart, Jean-Michel; Verron, Jacques


    The objective of this study is to explicitly simulate and quantify the uncertainty related to sea-level anomalies diagnosed from eddy-resolving ocean circulation models, in order to develop advanced methods suitable for addressing along-track altimetric data assimilation into such models. This work is carried out jointly with the MyOcean and SANGOMA (Stochastic Assimilation for the Next Generation Ocean Model Applications) consortium, funded by EU under the GMES umbrella over the 2012-2015 period. In this framework, a realistic circulation model of the North Atlantic ocean at 1/4° resolution (NATL025 configuration) has been adapted to include effects of unresolved scales on the dynamics. This is achieved by introducing stochastic perturbations of the equation of state to represent the associated model uncertainty. Assimilation experiments are designed using altimetric data from past and on-going missions (Jason-2 and Saral/AltiKA experiments, and Cryosat-2 for fully independent altimetric validation) to better control the Gulf Stream circulation, especially the frontal regions which are predominantly affected by the non-resolved dynamical scales. An ensemble based on such stochastic perturbations is then produced and evaluated -through the probabilistic criteria: the reliability and the resolution- using the model equivalent of along-track altimetric observations. These three elements (stochastic parameterization, ensemble simulation and 4D observation operator) are used together to perform optimal 4D analysis of along-track altimetry over 10-day assimilation windows. In this presentation, the results show that the free ensemble -before starting the assimilation process- well reproduces the climatological variability over the Gulf Stream area: the system is then pretty reliable but no informative (null probabilistic resolution). Updating the free ensemble with altimetric data leads to a better reliability and to an improvement of the information (resolution

  19. Investigating the Performance of the Jason-2/OSTM Radar Altimeter Over Lakes and Reservoirs (United States)

    Birkett, C. M.; Beckley, B.


    Many inland water investigations utilize archival and near-real time radar altimetry data to enable observation of the variation in surface water level. A multi-altimeter approach allows a more global outlook with improved spatial resolution, and combined long-term observations improve statistical analyses. Central to all programs is a performance assessment of each instrument. Here, we focus on data quantity and quality pertaining to the Poseidon-3 radar altimeter onboard the Jason-2/OSTM satellite.Utilizing an interim data set (IGDR), studies show that the new on-board DIODE/median and DIODE/DEM tracking modes are performing well, acquiring and maintaining the majority of lake and reservoir surfaces in varying terrains. The 20-Hz along-track resolution of the data, and particularly the availability of the range output from the ice-retracker algorithm, also improves the number of valid height measurements. Based on test-case lakes and reservoirs, output from the ice-retracker algorithm is also seen to have a clear advantage over the ocean-retracker having better height stability across calm and icy surfaces, a greater ability to gain coastline waters, and less sensitivity to loss of water surface when there is island contamination in the radar echo. Such on-board tracking and postprocessing retracking enables the lake waters to be quickly gained after coastline crossing. Values can range from <0.1 s to 2.5 s, but the majority of measurements are obtained in less than 0.4 s or <2.3 km from the coast. Validation exercises reveal that targets of 150 km2 surface area and 0.8 km width are able to be monitored offering greater potential to acquire lakes in the 100 C300 km2 size-category. Time series of height variations are also found to be accurate to 3 to 33 cm rms depending on target size and the presence of winter ice. These findings are an improvement over the IGDR/GDR results from the predecessor Jason-1 and TOPEX/Poseidon missions and can satisfy the accuracy

  20. Physical Retracking of Jason-1 LRM data for ocean surface height/gravity field determination (United States)

    Jain, Maulik; Baltazar Andersen, Ole; Stenseng, Lars; Dall, Jørgen


    Jason-1 Low Resolution Mode (LRM) waveforms can be processed to extract accurate heights of the ocean surface. These heights are adjusted taking into account various corrections available. Further the along surface slope/variation of these ocean heights can be used to make an estimation of the gravity field. An important part of this gravity field estimation is dependent on the way the LRM waveform is processed. Thus a physical model based on an error function is used, and the LRM waveforms are fit to this model. A processing system made up of 2 parameter and 3 parameter fitting models are used in order to extract the most reliable ocean surface heights. The quality of the processing system is judged by evaluating the standard deviation of the sea surface anomaly obtained after all corrections and the mean sea surface/geoid are removed. The lower the value of the standard deviation of the sea surface anomaly, the better the quality of processing is. Hence, different processing schemes are considered and evaluated in order to conclude towards the best retracking procedure which would eventually result in high accuracy gravity field estimations.

  1. Development of a Graphical Tool to integrate the Prometheus AEOlus methodology and Jason Platform

    Directory of Open Access Journals (Sweden)

    Rafhael CUNHA


    Full Text Available Software Engineering (SE is an area that intends to build high-quality software in a systematic way. However, traditional software engineering techniques and methods do not support the demand for developing Multiagent Systems (MAS. Therefore a new subarea has been studied, called Agent Oriented Software Engineering (AOSE. The AOSE area proposes solutions to issues related to the development of agent oriented systems. There is still no standardization in this subarea, resulting in several methodologies. Another issue of this subarea is that there are very few tools that are able to automatically generate code. In this work we propose a tool to support the Prometheus AEOlus Methodology because it provides modelling artifacts to all MAS dimensions: agents, environment, interaction, and organization. The tool supports all Prometheus AEOlus artifacts and can automatically generated code to the agent and interaction dimensions in the AgentSpeak Language, which is the language used in the Jason Platform. We have done some validations with the proposed tool and a case study is presented.

  2. El tacto de la poesía: P.o.E.M.M., de Jason Edward Lewis

    Directory of Open Access Journals (Sweden)

    Celia Corral Cañas


    Full Text Available he proposal of Jason Edward Lewis about tactile poetry means an innovation in the poetic field: it generates a new attitude in the reader, which is based on a continuous and required interaction. It adopts a playful and multimedia nature, and it achieves the harmony between aesthetic mechanisms and the topic itself. Under these qualities, it is originated the poetic nature of a genuine, original and outstanding creation, successfully located in the cultural paradigm of our times.

  3. Ocean Surface Topography Mission (OSTM) /Jason-3: Near Real-Time Altimetry Validation System (NRTAVS) QA Reports, 2015 - (NCEI Accession 0122600) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Jason-3 is the fourth mission in U.S.-European series of satellite missions that measure the height of the ocean surface. Scheduled to launch in 2015, the mission...

  4. Probabilistic evaluation of riprap failure under future uncertain flood conditions: the case study of river Kleine Emme (Switzerland) (United States)

    Jafarnejad, Mona; Pfister, Michael; Franca, Mário J.; Schleiss, Anton J.


    Potential failure for river bank protection measures is a critical issue to be evaluated for the safety and stability assessment. Moreover, uncertainties associated to flood conditions and sediment transport in rivers, as a possible result of climate change in the future, affects the safety level of such riverbank protection structures as riprap and walls. Bank failure can lead to uncontrolled erosion and flooding with disastrous consequences in residential areas or in critical infrastructures. The probabilistic analysis of failure on different mechanisms due to possible flood events and sediment transport is a principal step to assess embankment stability in future scenarios. Herein, a probabilistic risk assessment model to define the failure risk of river bank ripraps, developed based on Monte Carlo simulation and Moment Analysis Methods, is showed. This probabilistic simulation estimates the resistance of ripraps regarding varied flood and sediment transport scenarios in future. The failure probability of ripraps is assessed by a probabilistic function of the design safety factor. The probability of failure in different mechanisms such as direct block erosion, toe scouring and overtopping is defined by taking into account the modified bed-load transport due to a probabilistic function of the design discharge. This evaluation method is applied to a Swiss river located in Canton Lucerne, the Kleine Emme. The results highlight the failure probability of riverbank riprap associated to different mechanisms individually. A risk map to represent the risk of total failure along a longitudinal profile of the river is proposed.

  5. A Computer Clone of Human Expert for Mobility Management Scheme (E-MMS): Step toward Green Transportation (United States)

    Resdiansyah; O. K Rahmat, R. A.; Ismail, A.


    Green transportation refers to a sustainable transport that gives the least impact in terms of social and environmental but at the same time is able to supply energy sources globally that includes non-motorized transport strategies deployment to promote healthy lifestyles, also known as Mobility Management Scheme (MMS). As construction of road infrastructure cannot help solve the problem of congestion, past research has shown that MMS is an effective measure to mitigate congestion and to achieve green transportation. MMS consists of different strategies and policies that subdivided into categories according to how they are able to influence travel behaviour. Appropriate selection of mobility strategies will ensure its effectiveness in mitigating congestion problems. Nevertheless, determining appropriate strategies requires human expert and depends on a number of success factors. This research has successfully developed a computer clone system based on human expert, called E-MMS. The process of knowledge acquisition for MMS strategies and the next following process to selection of strategy has been encode in a knowledge-based system using a shell expert system. The newly developed computer cloning system was successfully verified, validated and evaluated (VV&E) by comparing the result output with the real transportation expert recommendation in which the findings suggested Introduction

  6. Biofilm formation of beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis isolates and its association with emm polymorphism. (United States)

    Ma, Jui-Shan; Chen, Sin-Yu; Lo, Hsueh-Hsia


    Biofilm formation has been well known as a determinant of bacterial virulence. Group G Streptococcus dysgalactiae subspecies equisimilis (SDSE), a relevant pathogen with increasing medical importance, was evaluated for the biofilm-forming potential. Microtiter plate assay was used to assess the most feasible medium for group G SDSE to form a biofilm. Among 246 SDSE isolates examined, 46.7%, 43.5%, 33.3%, and 26.4% of isolates showed moderate or strong biofilm-forming abilities using tryptic soy broth (TSB), brain heart infusion broth (BHI), Todd-Hewitt broth (THB), and C medium with 30 mM glucose (CMG), respectively. The addition of glucose significantly increased the biofilm-forming ability of group G SDSE. FCT (fibronectin-collagen-T-antigen) typing of SDSE was first undertaken and 11 FCT types were found. Positive associations of stG10.0 or negative associations of stG245.0, stG840.0, and stG6.1 with biofilm-forming ability of SDSE were, respectively, found. This was the first investigation demonstrating biofilm-forming potential in clinical group G SDSE isolates; also, some significant associations of biofilm-forming ability with certain emm types were presented. © 2017 APMIS. Published by John Wiley & Sons Ltd.

  7. Improving Jason-2 Sea Surface Heights within 10 km Offshore by Retracking Decontaminated Waveforms

    Directory of Open Access Journals (Sweden)

    Zhengkai Huang


    Full Text Available It is widely believed that altimetry-derived sea surface heights (SSHs in coastal zones are seriously degraded due to land contamination in altimeter waveforms from non-marine surfaces or due to inhomogeneous sea state conditions. Spurious peaks superimposed in radar waveforms adversely impact waveform retracking and hence require tailored algorithms to mitigate this problem. Here, we present an improved method to decontaminate coastal waveforms based on the waveform modification concept. SSHs within 10 km offshore are calculated from Jason-2 data by a 20% threshold retracker using decontaminated waveforms (DW-TR and compared with those using original waveforms and modified waveforms in four study regions. We then compare our results with retracked SSHs in the sensor geophysical data record (SGDR and with the state-of-the-art PISTACH (Prototype Innovant de Système de Traitement pour les Applications Côtières et l’Hydrologie and ALES (Adaptive Leading Edge Subwaveform products. Our result indicates that the DW-TR is the most robust retracker in the 0–10 km coastal band and provides consistent accuracy up to 1 km away from the coastline. In the four test regions, the DW-TR retracker outperforms other retrackers, with the smallest averaged standard deviations at 15 cm and 20 cm, as compared against the EGM08 (Earth Gravitational Model 2008 geoid model and tide gauge data, respectively. For the SGDR products, only the ICE retracker provides competitive SSHs for coastal applications. Subwaveform retrackers such as ICE3, RED3 and ALES perform well beyond 8 km offshore, but seriously degrade in the 0–8 km strip along the coast.

  8. High rate GPS positioning , JASON altimetry and marine gravimetry : monitoring the Antarctic Circumpolar Current (ACC) through the DRAKE campaigns. (United States)

    Melachroinos, S. A.; Biancale, R.; Menard, Y.; Sarrailh, M.


    The Drake campaign which took place from Jan 14, 2006 - 08 Feb, 2006 has been a very successful mission in collecting a wide range of GPS and marine gravity data all along JASON altimetry ground track n° 104. The same campaign will be repeated in 2009 along 028 and 104 JASON-2 ground track. The Drake Passage (DP) chokepoint is not only well suited geographically, as the Antarctic Circumpolar Current (ACC) is constricted to its narrowest extent of 700 km, but observations and models suggest that dynamical balances are particular effective in this area. Furthermore the space geodesy observations and their products provided from several altimetry missions (currently operating ENVISAT, JASON 1 and 2, GFO, ERS and other plannified for the future such as Altika, SWOT) require the cross comparison with independent geodetic techniques at the DP. The current experiment comprises a kinematic GPS and marine gravimetry Cal/Val geodetic approach and it aims to : validate with respect to altimetry data and surface models such a kinematic high frequency GPS technique for measuring sea state and sea surface height (SSH), compare the GPS SSH profiles with altimetry mean dynamic topography (MDT) and mean sea surface (MSS) models, give recommendations for future "offshore" Cal/Val activities on the ground tracks of altimeter satellites such as JASON-2, GFO, Altika using the GNSS technology etc. The GPS observations are collected from GPS antennas installed on a wave-rider buoy , aboard the R/V "Polarstern" and from continuous geodetic reference stations in the proximity. We also analyse problems related to the ship's attitude variations in roll, pitch and yaw and a way to correct them. We also give emphasis on the impact of the ship's acceleration profiles on the so called "squat effect" and ways to deal with it. The project will in particular benefit the GOCE mission by proposing to integrate GOCE in the ocean circulation study and validate GOCE products with our independent

  9. Distribution of virulence factors and association with emm polymorphism or isolation site among beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis. (United States)

    Lo, Hsueh-Hsia; Cheng, Wei-Shan


    Distribution of virulence factors and association with emm polymorphism or isolation site among beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis. Streptococcus dysgalactiae subspecies equisimilis (SDSE), the dominant human pathogenic species among group G streptococci, is the causative agent of several invasive and non-invasive diseases worldwide. However, limited information is available about the distribution of virulence factors among SDSE isolates, or their association with emm types and the isolation sites. In this study, 246 beta-hemolytic group G SDSE isolates collected in central Taiwan between February 2007 and August 2011 were under investigation. Of these, 66 isolates were obtained from normally sterile sites and 180 from non-sterile sites. emm typing revealed 32 types, with the most prevalent one being stG10.0 (39.8%), followed by stG245.0 (15.4%), stG840.0 (12.2%), stG6.1 (7.7%), and stG652.0 (4.1%). The virulence genes lmb (encoding laminin-binding protein), gapC (glyceraldehyde 3-phosphate dehydrogenase), sagA (streptolysin S), and hylB (hyaluronidase) existed in all isolates. Also, 99.2% of the isolates possessed slo (streptolysin O) and scpA (C5a peptidase) genes. In addition, 72.8%, 14.6%, 9.4%, and 2.4% of the isolates possessed the genes ska (streptokinase), cbp (putative collagen-binding protein, SDEG_1781), fbp (putative fibronectin-binding protein, SDEG_0161), and sicG (streptococcal inhibitor of complement), respectively. The only superantigen gene detected was spegg (streptococcus pyrogenic exotoxin G(dys) ), which was possessed by 74.4% of the isolates; these isolates correlated with non-sterile sites. Positive correlations were observed between the following emm types and virulence genes: stG10.0 and stG840.0 with spegg, stG6.1 and stG652.0 with ska, and stG840.0 with cbp. On the other hand, negative correlations were observed between the following: stG245.0, stG6.1, and stG652.0 types with spegg, stG10.0 with ska

  10. GAVDOS/west crete cal-val site: Over a decade calibrations for Jason series, SARAL/Altika, cryoSat-2, Sentinel-3 and HY-2 altimeter satellites

    DEFF Research Database (Denmark)

    Mertikas, Stelios; Tziavos, Ilias; Galanakis, Demitris

    This work presents and compares the latest altimeter calibration results for the Sentinel-3, Jason series, as well as the SARAL/AltiKa and the Chinese HY-2 missions, conducted at the Gavdos/Crete calibration/validation facilities. At first, the Jason altimeter calibration values will be given for...

  11. The Application of Jason-1 Measurements to Estimate the Global Near Surface Ocean Circulation for Climate Research (United States)

    Niiler, Peran P.


    The scientific objective of this research program was to utilize drifter, Jason-1 altimeter data and a variety of wind data for the determination of time mean and time variable wind driven surface currents of the global ocean. To accomplish this task has required the interpolation of 6-hourly winds on drifter tracks and the computation of the wind coherent motions of the drifters. These calculations showed that the Ekman current model proposed by Ralph and Niiler for the tropical Pacific was valid for all the oceans south of 40N latitude. Improvements to RN99 model were computed and poster presentations of the results were given in several ocean science venues, including the November 2004 GODAY meeting in St. Petersburg, FL.

  12. Marine geophysics. New global marine gravity model from CryoSat-2 and Jason-1 reveals buried tectonic structure. (United States)

    Sandwell, David T; Müller, R Dietmar; Smith, Walter H F; Garcia, Emmanuel; Francis, Richard


    Gravity models are powerful tools for mapping tectonic structures, especially in the deep ocean basins where the topography remains unmapped by ships or is buried by thick sediment. We combined new radar altimeter measurements from satellites CryoSat-2 and Jason-1 with existing data to construct a global marine gravity model that is two times more accurate than previous models. We found an extinct spreading ridge in the Gulf of Mexico, a major propagating rift in the South Atlantic Ocean, abyssal hill fabric on slow-spreading ridges, and thousands of previously uncharted seamounts. These discoveries allow us to understand regional tectonic processes and highlight the importance of satellite-derived gravity models as one of the primary tools for the investigation of remote ocean basins. Copyright © 2014, American Association for the Advancement of Science.

  13. Update of the corrective model for Jason-1 DORIS data in relation to the South Atlantic Anomaly and a corrective model for SPOT-5 (United States)

    Capdeville, Hugues; Štěpánek, Petr; Hecker, Louis; Lemoine, Jean-Michel


    After recalling the principle of the Jason-1 data corrective model in relation to the South Atlantic Anomaly (SAA) developed by Lemoine and Capdeville (2006), we present a model update which takes into account the orbit changes and the recent DORIS data. We propose also here a method to the International DORIS Service (IDS) Analysis Centers (ACs) in their contribution to the ITRF2014 for adding DORIS Jason-1 data into their solutions. When the Jason-1 satellite is added to the multi-satellite solution (orbit of inclination of 66° complements the polar-orbiting satellites), the stability of the geocenter Z-translation is improved (standard deviation of 11.5 mm against 16.5 mm). In a second part we take advantage of a high-energy particles dosimeter (CARMEN) on-board Jason-2 to improve the corrective model of Jason-1. We completed a correlation study showing that the CARMEN >87 MeV integrated proton flux map averaged over the period 2009-2011 is the energy band of the CARMEN maps which are the most coherent with the one obtained from Jason-1 DORIS measurements. The model based on the Jason-1 map and the one based on the CARMEN map are then compared in terms of orbit determination and station position estimation. We derive and validate a SPOT-5 data corrective model. We determine the SAA grid at the altitude of SPOT-5 from the frequency time derivative of the on-board frequency offsets and estimated the model parameters. We demonstrate the impact of the SPOT-5 data corrective model on the Precise Orbit Determination and the station position estimation from the weekly solutions, based on two individual Analysis Centers solutions, GOP (Geodetic Observatory Pecny) and GRG (Groupe de Recherche de Géodésie Spatiale). The SPOT-5 data corrective model significantly improves the Precise Orbit Determination (reduction of 1.4% in 2013 of RMS of the fit, reduction of 25% in normal direction of arc overlap RMS) and the overall statistics of the station position estimation

  14. Review of inputs provided to Jason Associates Corporation in support of RWEV-REP-001, the Analysis of Postclosure Groundwater Impacts report.

    Energy Technology Data Exchange (ETDEWEB)

    Bryan, Charles R.; Weck, Philippe F.; Vaughn, Palmer; Arnold, Bill Walter


    Report RWEV-REP-001, Analysis of Postclosure Groundwater Impacts for a Geologic Repository for the Disposal of Spent Nuclear Fuel and High Level Radioactive Waste at Yucca Mountain, Nye County, Nevada was issued by the DOE in 2009 and is currently being updated. Sandia National Laboratories (SNL) provided support for the original document, performing calculations and extracting data from the Yucca Mountain Performance Assessment Model that were used as inputs to the contaminant transport and dose calculations by Jason Associates Corporation, the primary developers of the DOE report. The inputs from SNL were documented in LSA-AR-037, Inputs to Jason Associates Corporation in Support of the Postclosure Repository Supplemental Environmental Impact Statement. To support the updating of the original Groundwater Impacts document, SNL has reviewed the inputs provided in LSA-AR-037 to verify that they are current and appropriate for use. The results of that assessment are documented here.

  15. CryoSat-2 science algorithm status, expected future improvements and impacts concerning Sentinel-3 and Jason-CS missions (United States)

    Cullen, R.; Wingham, D.; Francis, R.; Parrinello, T.


    With CryoSat-2 soon to enter its second year of post commissioning operations there is now sufficient experience and evidence showing improvements of the SIRAL's (Synthetic interferometric radar altimeter) SAR and SARIn modes over conventional pulse-width limited altimeters for both the targeted marine/land ice fields but also for non mission relevant surfaces such as the ocean, for example. In the process of understanding the CryoSat data some side effects of the end-to-end platform measurement and ground retrieval system have been identified and whilst those key to mission success are understood and are being handled others, remain open and pave the way to longer term fine-tuning. Of interest to the session will be a summary of the manditory changes made during 2011 to all the modes of CryoSat-2 science processing with a view to longer term algorithm improvements that could benefit the planned mid-to-late nominal operations re-processing. Since some of the science processor improvements have direct implication to the SAR mode processing of Sentinel-3 and Jason-CS science then these will also be highlighted. Finally a summary of the CryoSat-2 in-orbit platform and payload performances and their stability will also be provided. Expectations of the longer term uses of CryoSat's primary sensor (SIRAL) and its successors will be discussed.

  16. Phase I for the Use of TOPEX-Poseidon and Jason-1 Radar Altimetry to Monitor Coastal Wetland Inundation and Sea Level Rise in Coastal Louisiana (United States)

    Brozen, Madeline; Batina, Matthew; Parker, Stephen; Brooks, Christopher


    The objective of the first phase of this project was to determine the feasibility of applying satellite altimetry data to monitor sea level rise and inundation within coastal Louisiana. Global sea level is rising, and coastal Louisiana is subsiding. Therefore, there is a need to monitor these trends over time for coastal restoration and hazard mitigation efforts. TOPEX/POSEIDON and Jason-data are used for global sea level estimates and have also been demonstrated successfully in water level studies of lakes, river basins, and floodplains throughout the world. To employ TOPEX/POSEIDON and Jason-1 data in coastal regions, the numerous steps involved in processing the data over non-open ocean areas must be assessed. This project outlined the appropriate methodology for processing non-open ocean data, including retracking and atmospheric corrections. It also inventoried the many factors in coastal land loss including subsidence, sea level rise, coastal geomorphology, and salinity levels, among others, through a review of remote sensing and field methods. In addition, the project analyzed the socioeconomic factors within the Coastal Zone as compared to the rest of Louisiana. While sensor data uncertainty must be addressed, it was determined that it is feasible to apply radar altimetry data from TOPEX/POSEIDON and Jason 1 to see trends in change within Coastal Louisiana since

  17. Assessment of radar altimetry correction slopes for marine gravity recovery: A case study of Jason-1 GM data (United States)

    Zhang, Shengjun; Li, Jiancheng; Jin, Taoyong; Che, Defu


    Marine gravity anomaly derived from satellite altimetry can be computed using either sea surface height or sea surface slope measurements. Here we consider the slope method and evaluate the errors in the slope of the corrections supplied with the Jason-1 geodetic mission data. The slope corrections are divided into three groups based on whether they are small, comparable, or large with respect to the 1 microradian error in the current sea surface slope models. (1) The small and thus negligible corrections include dry tropospheric correction, inverted barometer correction, solid earth tide and geocentric pole tide. (2) The moderately important corrections include wet tropospheric correction, dual-frequency ionospheric correction and sea state bias. The radiometer measurements are more preferred than model values in the geophysical data records for constraining wet tropospheric effect owing to the highly variable water-vapor structure in atmosphere. The items of dual-frequency ionospheric correction and sea state bias should better not be directly added to range observations for obtaining sea surface slopes since their inherent errors may cause abnormal sea surface slopes and along-track smoothing with uniform distribution weight in certain width is an effective strategy for avoiding introducing extra noises. The slopes calculated from radiometer wet tropospheric corrections, and along-track smoothed dual-frequency ionospheric corrections, sea state bias are generally within ±0.5 microradians and no larger than 1 microradians. (3) Ocean tide has the largest influence on obtaining sea surface slopes while most of ocean tide slopes distribute within ±3 microradians. Larger ocean tide slopes mostly occur over marginal and island-surrounding seas, and extra tidal models with better precision or with extending process (e.g. Got-e) are strongly recommended for updating corrections in geophysical data records.

  18. Assessment of Current Estimates of Global and Regional Mean Sea Level from the TOPEX/Poseidon, Jason-1, and OSTM 17-Year Record (United States)

    Beckley, Brian D.; Ray, Richard D.; Lemoine, Frank G.; Zelensky, N. P.; Holmes, S. A.; Desal, Shailen D.; Brown, Shannon; Mitchum, G. T.; Jacob, Samuel; Luthcke, Scott B.


    The science value of satellite altimeter observations has grown dramatically over time as enabling models and technologies have increased the value of data acquired on both past and present missions. With the prospect of an observational time series extending into several decades from TOPEX/Poseidon through Jason-1 and the Ocean Surface Topography Mission (OSTM), and further in time with a future set of operational altimeters, researchers are pushing the bounds of current technology and modeling capability in order to monitor global sea level rate at an accuracy of a few tenths of a mm/yr. The measurement of mean sea-level change from satellite altimetry requires an extreme stability of the altimeter measurement system since the signal being measured is at the level of a few mm/yr. This means that the orbit and reference frame within which the altimeter measurements are situated, and the associated altimeter corrections, must be stable and accurate enough to permit a robust MSL estimate. Foremost, orbit quality and consistency are critical to satellite altimeter measurement accuracy. The orbit defines the altimeter reference frame, and orbit error directly affects the altimeter measurement. Orbit error remains a major component in the error budget of all past and present altimeter missions. For example, inconsistencies in the International Terrestrial Reference Frame (ITRF) used to produce the precision orbits at different times cause systematic inconsistencies to appear in the multimission time-frame between TOPEX and Jason-1, and can affect the intermission calibration of these data. In an effort to adhere to cross mission consistency, we have generated the full time series of orbits for TOPEX/Poseidon (TP), Jason-1, and OSTM based on recent improvements in the satellite force models, reference systems, and modeling strategies. The recent release of the entire revised Jason-1 Geophysical Data Records, and recalibration of the microwave radiometer correction also

  19. Simultaneous isolation of emm89-type Streptococcus pyogenes strains with a wild-type or mutated covS gene from a single streptococcal toxic shock syndrome patient. (United States)

    Masuno, Katsuaki; Okada, Ryo; Zhang, Yan; Isaka, Masanori; Tatsuno, Ichiro; Shibata, Shinichiro; Hasegawa, Tadao


    Streptococcal toxic shock syndrome (STSS) is a re-emerging infectious disease in many developed countries. Recent studies have suggested that mutations in CovRS, a two-component regulatory system in Streptococcus pyogenes, play important roles in the pathogenesis of STSS. However, in vivo evidence of the significance of CovRS in human infections has not been fully demonstrated. We investigated five S. pyogenes strains isolated simultaneously from the pharynx, sputum, knee joint, cerebrospinal fluid and blood of a single STSS patient. All were emm89-type strains, and multilocus sequence typing (MLST) analysis revealed that the strains of pharynx and blood were isogenic. The growth rates of the strains from pharynx and sputum were faster than those of the other strains. Protein profiles of the culture supernatants of strains from the pharynx and sputum were also different from those of the other strains. Sequence analyses revealed that strains from the knee joint, cerebrospinal fluid and blood contained a single nucleotide difference in the covS coding region, resulting in one amino acid change, compared with the other strains. Introduction of a plasmid containing the covS gene from the pharynx strain to the blood strain increased the production of SpeB protein. This suggests that the one amino acid alteration in CovS was relevant to pathogenesis. This report supports the idea that mutated CovS plays important roles in vivo in the dissemination of S. pyogenes from the upper respiratory tract of human to aseptic tissues such as blood and cerebrospinal fluid.

  20. Ongoing outbreak of invasive and non-invasive disease due to group A Streptococcus (GAS) type emm66 among homeless and people who inject drugs in England and Wales, January to December 2016. (United States)

    Bundle, Nick; Bubba, Laura; Coelho, Juliana; Kwiatkowska, Rachel; Cloke, Rachel; King, Sarah; Rajan-Iyer, Jill; Courtney-Pillinger, Max; Beck, Charles R; Hope, Vivian; Lamagni, Theresa; Brown, Colin S; Jermacane, Daiga; Glass, Rachel; Desai, Monica; Gobin, Maya; Balasegaram, Sooria; Anderson, Charlotte


    We report an outbreak of invasive and non-invasive disease due to an unusual type of Streptococcus pyogenes (group A Streptococcus, emm66) among a vulnerable, largely homeless population in southern England and Wales, detected in September 2016. Twenty-seven confirmed cases were subsequently identified between 5 January and 29 December 2016; 20 injected drugs and six reported problematic alcohol use. To date, we have ruled out drug-related vehicles of infection and identified few common risk factors. This article is copyright of The Authors, 2017 .

  1. Ganga-Brahmaputra river discharge from Jason-2 radar altimetry: An update to the long-term satellite-derived estimates of continental freshwater forcing flux into the Bay of Bengal

    Digital Repository Service at National Institute of Oceanography (India)

    Papa, F.; Bala, S.K.; Pandey, R.K.; Durand, F.; Gopalakrishna, V.V.; Rahman, A.; Rossow, W.B.

    TOPEX-Poseidon, ERS-2 and ENVISAT, and is now extended using Jason-2. To take full advantages of the new availability of in situ rating curves, the processing scheme is adapted and the adjustments of the methodology are discussed here. First, using a...


    Directory of Open Access Journals (Sweden)

    Dewangga Eka Mahardian


    Full Text Available Indonesia adalah negara maritim dimana memiliki wilayah laut sekitar 70% sehingga segala aktifitas sangat dipengaruhi oleh kondisi laut. Sea surface high (SSH merupakan tinggi permukaan air laut di atas ellipsoid. Pengkajian tentang sea surface high (SSH sangat penting dilakukan di Indonesia untuk memperoleh informasi spasial tentang kondisi perairannya. Saat ini telah dikembangkan suatu sistem satelit yang mempunyai obyek penelitian mengamati kondisi perairan yakni satelit altimetri Jason-2.Metode analisa perbandingan tinggi permukaan laut retracking dari data SGDR dengan tinggi permukaan laut non retracking dari data GDR menggunakan metode Center of gravity. Metode ini digunakan untuk mendapatkan  sea surface high retracking. Pengolahan data netcdf satelit altimetri jason-2 menggunakan software radar altimetry toolbox (BRAT dan matrix laboratory. Pengolahan data tinggi permukaan laut dilakukan tiap pass perbulan pada tahun 2011.Hasil penelitian SSH pada 2011 didapatkan nilai SSH onboard  6,0430 m – 28,1084 m. Banyak faktor yang menyebabkan tinggi rendah SSH pada daerah pesisir yakni Ketinggian air laut , morfologi pantai , Iklim dan cuaca. Dari beberapa faktor tersebut , ketinggian air laut dapat langsung di olah dari satelit altimetri, didapatkan Ketinggian air laut onboard berkisar 5,7611 m – 28,2212 m.Hasil penelitian dari proses retracking SSH OCOG menujukan bahwa nilai SSH pada lintasan satelit dari daratan ke lautan (pass genap lebih besar  daripada lautan ke daratan (pass ganjil. Yang disebabkan oleh pantulan dan noise dari daratan yang relatif besar. Selain itu hasil ploting SSH OCOG masih sangat noise dibandingkan SSH onboard / SSH non retracking tetapi SSH memiliki keuntungan data lebih luas mencakup wilayah pesisir daripada SSH onboard.   

  3. Management of waste associated with the decommissioning of the JASON research reactor and the nuclear laboratories at the Royal Naval College Greenwich

    International Nuclear Information System (INIS)

    Beeley, P.A.; Lockwood, R.J.S.; Hoult, D.; Major, R.


    In 1996 the UK Government announced that the Royal Naval College, Greenwich would pass to non-defence use by the millennium. As a consequence of this decision, the decommissioning of the JASON 10 kW Argonaut research reactor and the relocation of the Department of Nuclear Science and Technology (DNST) were approved by the Ministry of Defence. The decommissioning of the reactor commenced in November 1997 while DNST remained operational until October 1998. The DNST was responsible for education and training in support of the UK Naval Nuclear Propulsion Programme and operated academic laboratories for atomic and nuclear physics, health physics, instrument calibration and radiochemistry. Therefore, besides the nuclear reactor, open and sealed sources (alpha, beta and gamma), intense x-ray (sealed tube) and gamma-ray ( 60 CO and 137 Cs) sources and small 241 Am/Be neutron sources had been used in the Department for over 35 years. Decommissioning of all facilities was therefore a relatively complex task and the management of waste streams was challenging. All facilities were successfully decommissioned for unrestricted site release by December 1999 and this paper will describe the methodology used for preparation, storage, characterisation and disposal of all waste streams. The most significant waste management task during this decommissioning programme was that associated with the JASON reactor. It should be noted that the JASON reactor fuel was not designated as nuclear waste, the fuel removal and storage were covered under separate contracts and therefore no high level waste was generated. With respect to other waste streams, a combination of Monte Carlo modelling and selective sampling and analysis of the reactor materials was used to estimate the quantities of waste as follows: LLW - 76 tonnes packed in 4 half height ISO containers; LLW - 6 Tonnes packed in 200litre drums in 1 full height ISO container; ILW - 60 kg packed in approved shielded containers; FRW -121

  4. Jason: heavy-ion-driven inertial fusion

    International Nuclear Information System (INIS)

    Callan, C.G. Jr.; Dashen, R.F.; Garwin, R.L.; Muller, R.A.; Richter, B.; Rosenbluth, M.N.


    A few of the problems in heavy-ion-driven inertial-fusion systems are reviewed. Nothing was found within the scope of this study that would in principle bar such systems from delivering the energy and peak power required to ignite the fuel pellet. Indeed, ion-fusion seems to show great promise, but the conceptual design of ion-fusion systems is still in a primitive state. A great deal of work, mostly theoretical, remains to be done before proceeding with massive hardware development. Conclusions are given about the state of the work


    African Journals Online (AJOL)

    toxicity of the two dyes was attributed to dilference in dye content and molecular weight. Q1}!/ISEM. Dyes are extensively used in the ... et al, 1990). The discharge of dye wastewater into the environment causes various pollution ... toxicity of a chemical to microoganisms is normally measured in terms of growth inhibition ...

  6. Open system sulphate reduction in a diagenetic environment - Isotopic analysis of barite (δ34S and δ18O) and pyrite (δ34S) from the Tom and Jason Late Devonian Zn-Pb-Ba deposits, Selwyn Basin, Canada (United States)

    Magnall, J. M.; Gleeson, S. A.; Stern, R. A.; Newton, R. J.; Poulton, S. W.; Paradis, S.


    Highly positive δ34S values in sulphide minerals are a common feature of shale hosted massive sulphide deposits (SHMS). Often this is attributed to near quantitative consumption of seawater sulphate, and for Paleozoic strata of the Selwyn Basin (Canada), this is thought to occur during bacterial sulphate reduction (BSR) in a restricted, euxinic water column. In this study, we focus on drill-core samples of sulphide and barite mineralisation from two Late Devonian SHMS deposits (Tom and Jason, Macmillan Pass, Selwyn Basin), to evaluate this euxinic basin model. The paragenetic relationship between barite, pyrite and hydrothermal base metal sulphides has been determined using transmitted and reflected light microscopy, and backscatter electron imaging. This petrographic framework provides the context for in-situ isotopic microanalysis (secondary ion mass spectrometry; SIMS) of barite and pyrite. These data are supplemented by analyses of δ34S values for bulk rock pyrite (n = 37) from drill-core samples of un-mineralised (barren), siliceous mudstone, to provide a means by which to evaluate the mass balance of sulphur in the host rock. Three generations of barite have been identified, all of which pre-date hydrothermal input. Isotopically, the three generations of barite have overlapping distributions of δ34S and δ18O values (+22.5‰ to +33.0‰ and +16.4‰ to +18.3‰, respectively) and are consistent with an origin from modified Late Devonian seawater. Radiolarian tests, enriched in barium, are abundant within the siliceous mudstones, providing evidence that primary barium enrichment was associated with biologic activity. We therefore propose that barite formed following remobilisation of productivity-derived barium within the sediment, and precipitated within diagenetic pore fluids close to the sediment water interface. Two generations of pyrite are texturally associated with barite: framboidal pyrite (py-I), which has negative δ34S values (-23‰ to -28

  7. Critical experiments on interaction systems using STACY and their analytical evaluation

    International Nuclear Information System (INIS)

    Tonoike, Kotaro; Yamamoto, Toshihiro; Miyoshi, Yoshinori


    A series of experiments with neutron interactive cores that consisted of two slab tanks was conducted to measure the neutronic characteristics of the multiple-unit system. The measured characteristics are useful to discuss the issues of criticality safety design such as the modeling scheme of multiple-unit systems, the accuracy of computation methods of the weekly-coupled system, and so far. In this presentation, conditions of the series of experiments will be outlined. Their analytical evaluation for the validation of computational methods will be also discussed. (author)

  8. 76 FR 30974 - Jason Incorporated, Janesville Accoustics Division, Subsidiary of Jason Partners Holdings LLC... (United States)


    ... Design and Gill Staffing, Grand Rapids, Michigan; Amended Certification Regarding Eligibility To Apply... industry and seat backs for the automotive and furniture industries. The Department's Notice will soon be... for workers of the subject firm. The company reports that workers leased from Imperial Design and Gill...

  9. Dadaismi emme Hannah Höch / Ragna Nukk

    Index Scriptorium Estoniae

    Nukk, Ragne, 1984-


    Saksa kunstniku Hannah Höchi näitus "Personal is Political. Hannah Höch ja tema kunsti tõlgendus" Tallinna Kunstihoones 17. oktoobrini 2010, kuraator Reet Varblane. Eksponeeritakse ka ameerika kunstniku Martha Rosleri, eesti kunstnike Silvia Jõgeveri, Valve Janovi jt. töid

  10. The AORTA Architecture : Integrating Organizational Reasoning in Jason

    NARCIS (Netherlands)

    Schmidt Jensen, A.; Dignum, V.; Villadsen, J.


    Open systems are characterized by a diversity of heterogeneous and autonomous agents that act according to private goals, and with a behavior that is hard to predict. They can be regulated through organizations similar to human organizations, which regulate the agents' behavior space and describe

  11. Improving the Quality of E-Learning: Lessons from the eMM (United States)

    Marshall, S.


    The quality of e-learning can be defined in many different ways, reflecting different stakeholders and the complexity of the systems and processes used in higher education. These different conceptions of quality can be mutually contradictory and, while politically significant, may also be beyond the direct control or influence of institutional…

  12. Picturing the Earth: Geoscience in Public Art Abstract for AGU 2013: Geoscience through the Lens of Art. Author: Stacy Levy, Sere Ltd., Spring Mills, PA (Invited) (United States)

    Levy, S.


    Public places such as parks, urban plazas, transportation centers and educational institutions offer the opportunity to reach many people in the course of daily life. Yet these public spaces are often devoid of any substantive information about the local environment and natural processes that have shaped it. Art is a particularly effective means to visualize environmental phenomena. Art has the ability to translate the processes of nature into visual information that communicates with clarity and beauty. People often have no connection to the world through which they walk: no sense of their place in the local watershed or where the rainwater goes once it hits the ground. Creating an awareness of place is critical first step for people to understand the changes in their world. Art can be a gateway for understanding geo-scientific concepts that are not frequently made accessible in a visual manner And art requires scientific knowledge to inform an accurate visualization of nature. Artists must collaborate with scientists in order to create art that informs the public about environmental processes. There is a new current in the design world that combines art and technology to create artful solutions to site issues such as storm water runoff, periodic flooding and habitat destruction. Instead of being considered functionless, art is now given a chance to do some real work on the site. This new combination of function and aesthetic concerns will have a major impact on how site issues are perceived. Site concerns that were once considered obstacles can become opportunities to visualize and celebrate how problems can be solved. This sort of artful solutions requires teamwork across many disciplines. In my presentation I will speak about various ways of I have visualized the invisible processes of the natural world in my projects. I will share eight of my permanent and temporary art commissions that are collaborations with scientists and engineers. These works reveal wetland habitats, tides, prevailing winds, rain and microorganisms, and water pollution. In examining each project I will detail the essential collaborations with scientists and engineers that brought the projects to fruition. I will discuss how the cross-discipline approach of scientists, engineers and designers made effective and artful solutions to site issues, and created visually stimulating and educational places. I will also look at the role of truth and metaphor in art and compare how accuracy and data collection have differing thresholds in art and in science.

  13. Strategická hra v multi-agentním prostředí Jason


    Vais, Roman


    Práce se zabývá umělou inteligencí využívanou v~oblasti počítačových her, zejména pak tzv. strategií v~reálném čase, a implementuje rozšíření pro jednu z~těchto her. Analyzuje možnosti využití přístupu multi-agentních systémů právě pro účely umělé inteligence v~počítačových hrách. Zabývá se konceptem swarm inteligece (inteligence roje), jako vhodné, ale nevyužívané, varianty umělé inteligence nejen pro strategické hry. Mimo jiné se tato práce pokouší o~volbu vhodné reprezentace vjemů jednotli...

  14. Game, game, game and again game, de Jason Nelson: aspectos da contemporaneidade

    Directory of Open Access Journals (Sweden)

    Flavio Pereira Senra


    Full Text Available Embora pensadores como o escritor Mario Vargas Llosa afirmem que os tempos hodiernos têm como característica principal a frivolidade, por conta da velocidade e quantidade de informações a serem digeridas diariamente, artistas em sua pulsão criativa exploram tais paradoxos de grandeza/pequenez em suas obras de arte. Este artigo visa apreender na obra Game, game, game and again game aspectos da contemporaneidade, como o conceito de lúdico e a enorme gama de entretenimentos voltados a um público imerso na indústria da cultura, através da forma como eles são trabalhados junto a conceitos como interatividade como forma de coautoria da obra de arte, finitude artística e permanência no meio digital, e transmidialidade na criação estética.

  15. Thorvaldsens Jason med det gyldne skind som ophævelsen af antikken

    DEFF Research Database (Denmark)

    Holm, Henrik


    Bertel Thorveldsen, Norma Bryson, Jacques Derrida, Sigmund Freud, Jacques Lacan, Kunsthistorie, æstetik, skulptur......Bertel Thorveldsen, Norma Bryson, Jacques Derrida, Sigmund Freud, Jacques Lacan, Kunsthistorie, æstetik, skulptur...

  16. Sustaining the natural and economical resources of the Lac Courte Oreilles, Leslie Isham; Jason Weaver

    Energy Technology Data Exchange (ETDEWEB)

    Isham, Leslie; Weaver, Jason


    The Lac Courte Oreilles Band of Lake Superior Chippewa Indians, located in northwest Wisconsin has developed a project, entitled Sustaining the Natural and Economic Resources of the LCO Ojibwe. This technical report is a summary of the project.

  17. Kithuri e. Kinoti, leonard A. Jason, & gary W. harper DePaul ...

    African Journals Online (AJOL)

    survey measuring possible psychosocial determinants of alcohol, khat and bhang (i.e., marijuana) ... The implications of these findings are ... 108 are from hospital and school settings. For ex- ample, Ndetei (1984) found that among first time admissions of patients aged 18-65 in Ke- nyatta national hospital, only two of 83 par ...

  18. 75 FR 1623 - Jason Vale; Denial of Hearing; Final Debarment Order (United States)


    ... the president of Christian Brother's Inc., guilty of three counts of criminal contempt in violation of... conduct relating to the regulation of a drug product. Mr. Vale's convictions for contempt stemmed from his... contempt trial showed that, in violation of the two injunctions, he continued to promote and sell amygdalin...

  19. Incidence and Characteristics of Scarlet Fever, South Korea, 2008–2015 (United States)

    Park, Duck Woong; Kim, Sun-Hee; Park, Jung Wook; Kim, Min-Ji; Cho, Sun Ju; Park, Hye Jung; Jung, So Hyang; Seo, Mi Hee; Lee, Yong Seok; Kim, Byung Hee; Min, Hyeran; Lee, Su Ya; Ha, Dong Ryong; Kim, Eun Sun


    The incidence rate for scarlet fever in South Korea is rising. During 2008–2015, we collected group A Streptococcus isolates and performed emm and exotoxin genotyping and disk-diffusion antimicrobial tests. Scarlet fever in South Korea was most closely associated with emm types emm4, emm28, emm1, and emm3. In 2015, tetracycline resistance started increasing. PMID:28322696

  20. Incidence and Characteristics of Scarlet Fever, South Korea, 2008-2015. (United States)

    Park, Duck Woong; Kim, Sun-Hee; Park, Jung Wook; Kim, Min-Ji; Cho, Sun Ju; Park, Hye Jung; Jung, So Hyang; Seo, Mi Hee; Lee, Yong Seok; Kim, Byung Hee; Min, Hyeran; Lee, Su Ya; Ha, Dong Ryong; Kim, Eun Sun; Hong, Yeongjin; Chung, Jae Keun


    The incidence rate for scarlet fever in South Korea is rising. During 2008-2015, we collected group A Streptococcus isolates and performed emm and exotoxin genotyping and disk-diffusion antimicrobial tests. Scarlet fever in South Korea was most closely associated with emm types emm4, emm28, emm1, and emm3. In 2015, tetracycline resistance started increasing.

  1. About Face

    Medline Plus

    Full Text Available ... Up Close As a combat photographer, Stacy Pearsall sees the unspeakable. Rather than lose what she values most, she turns to treatment. Hear Stacy's story See all Up Close stories → Treatment Works Follow Veterans ...

  2. About Face

    Medline Plus

    Full Text Available ... can treatment help me? → Our advice to you. → Up Close As a combat photographer, Stacy Pearsall sees ... turns to treatment. Hear Stacy's story See all Up Close stories → Treatment Works Follow Veterans as they ...

  3. About Face

    Medline Plus

    Full Text Available ... Stacy Pearsall sees the unspeakable. Rather than lose what she values most, she turns to treatment. Hear Stacy's story See all Up Close stories → Treatment Works Follow Veterans as they share their experiences with ...

  4. The Application of Jason-Measurements to Estimate the Global Near Surface Ocean Circulation for Climate Research (United States)

    Niiler, Pearn P.


    The scientific objective of this research program were to utilize drifter and satellite sea level data for the determination of time mean and time variable surface currents of the global ocean. To accomplish these tasks has required the processing of drifter data to include a wide variety of different configurations of drifters into a uniform format and to process the along track satellite altimeter data for computing the geostrophic current components normal to the track. These tasks were accomplished, which resulted in an increase of drifter data by about 40% and the development of new algorithms for obtaining satellite derived geostrophic velocity data that was consistent with the drifter observations of geostrophic time-variable currents. The methodologies and the research results using these methodologies were reported in the publications listed in this paper.

  5. Free and Forced Rossby Waves in the Western South China Sea Inferred from Jason-1 Satellite Altimetry Data

    Directory of Open Access Journals (Sweden)

    Dongxiao Wang


    Full Text Available Data from a subsurface mooring deployed in the western South China Sea shows clear intra-seasonal oscillations (ISO at the period of 40~70 days. Analysis of remotelysensed sea surface height (SSH anomalies in the same area indicates that these ISO signals propagate both eastward and westward. Time-longitude diagrams of ISO signals in SSH anomalies and wind-stress curl indicate that the eastward propagating SSH anomalies is forced by wind-stress curl. This is also confirmed by lag correlation between SSH anomalies and the wind-stress-curl index (wind stress curl averaged over 109.5ºE -115ºE and 12ºN -13.5ºN. Lag correlation of SSH anomaly suggests that the westward propagating signals are free Rossby waves.

  6. National Department of Defense Surveillance for Clinical Group A Streptococcal Isolates, Antibiotic Resistance, and emm Gene Types from 8 Basic Training Military Sites (United States)


    Southeast Asia. J Infect Dis 1994;169:658-61. 31. Facklam RF, Martin DR, Lovegren M, et al. Extension of the Lancefield Classification for Group A...NAVAL HEALTH RESEARCH CENTER NATIONAL DEPARTMENT OF DEFENSE SURVEILLANCE FOR CLINICAL GROUP A STREPTOCOCCAL ISOLATES, ANTIBIOTIC...Ryan G. C. Gray DoD S. pyogenes Surveillance Group Report No. 03-01 Approved for public release; distribution unlimited

  7. Patterns of host ant use by sympatric populations of Maculinea alcon and <em>M. 'rebeli' in the Carpathian Basin

    DEFF Research Database (Denmark)

    Tartally, A.; Nash, David Richard; Lengyel, S.


    , including host plant and host ant species. However, recent genetic evidence has questioned their separation as good species. Here we compare the use of host ants by M. alcon and M. ‘rebeli’ at the regional scale in NE-Hungary and Transylvania (Romania), where molecular studies have found no species......Maculinea butterflies show social parasitism via obligatory myrmecophily as their larvae are adopted and raised to pupation by Myrmica ants. Suitable hosts differ for different Maculinea species, and host ant specificity can further differ at the population-level. Although early studies suggested...... single ant species as main hosts for each Maculinea species, it has recently become clear that their host ant specificity is more complex. Maculinea alcon and Maculinea ‘rebeli’ have variously been separated according to adult and larval morphology, phenology, and their use of different ecosystems...

  8. Scientific opinion on a quantitative pathway analysis of the likelihood ofTilletia indica em>M. introduction into EU with importation of US wheat

    DEFF Research Database (Denmark)

    Baker, R.; Candresse, T.; Dormannsné Simon, E.


    wheat model for several parameters related to EU country characteristics. Further research is needed to refine parameter values, to reduce uncertainty and to determine relationship between teliospores number on soil surface and number of bunted kernels resulting from infection of a wheat plant...... the US bunted kernel standard would provide equivalent protection against introduction of Tilletia indica into EU, compared to the existing EU import requirement. The Panel on Plant Health reviewed pathway scenarios, model and parameters and found several shortcomings regarding model equations....... The Panel concluded that the US bunted kernel standard does not provide a level of protection equivalent to EU requirements and that such level of protection could only be warranted by measures which include testing at harvest and before shipment to detect T. indica teliospores....

  9. Characterization of Streptococcus pyogenes isolates responsible for adult meningitis in France from 2003 to 2013. (United States)

    Plainvert, Céline; Doloy, Alexandra; Joubrel, Caroline; Maataoui, Naouale; Dmytruk, Nicolas; Touak, Gérald; Collobert, Gislène; Fouet, Agnès; Poyart, Claire; Loubinoux, Julien


    Sixty-three cases of Streptococcus pyogenes meningitis in adults were studied. Three predominant emm types were associated with meningitis: emm1 (44%), emm3 (11%), and emm6 (11%). Streptococcal toxic shock syndrome and mortality rates were 40% and 38%, respectively. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Food allergy

    National Research Council Canada - National Science Library

    Maleki, Soheila J; Burks, A. Wesley; Helm, Ricki M


    ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii ix I. CLINICAL ASPECTS 1. Clinical Manifestations of Food Allergic Disease * Tamara T. Perry, Amy M. Scurlock, and Stacie M. Jones...

  11. Hernies inguinales a l’hôpital Jason Sendwe de Lubumbashi en République Démocratique du Congo. À propos de 41 cas


    Mukuku OK; Wakunga E; Bugeme M; Kitembo M; Kabwit D; Wakunga W


    RÉSUMÉ Objectifs. Déterminer la fréquence des hernies inguinales et de ses complications et rapporter les aspects cliniques et évolutifs des hernies inguinales (durée d’hospitalisation – mortalité). Matériel et méthode. Il s’agit d’une étude rétrospective ayant colligé 41 dossiers de patients opérés pour hernie inguinale du 1er janvier 2008 au 31 décembre 2009 à l’hôpital Sendwe de Lubumbashi (RD. Congo). Les aspects épidémiologiques, cliniques et évolutifs ont été étudiés. Résultats...

  12. Work and Rest Patterns and Psychomotor Vigilance Performance of Crewmemebers of the USS Jason Dunham: A Comparison of the 3/9 and 6/6 Watchstanding Schedules (United States)


    coworker support and the social interactions that are vital for good morale and mental health) ( Maslow , 1943; Taormina, 1997). Although this study... Maslow , A. H. (1943). A theory of human motivation. Psychological Review, 50, 370–396. Mason, D. R. (2009). A comparative analysis between the Navy

  13. A Conceptually Simple Modeling Approach for Jason-1 Sea State Bias Correction Based on 3 Parameters Exclusively Derived from Altimetric Information

    Directory of Open Access Journals (Sweden)

    Nelson Pires


    Full Text Available A conceptually simple formulation is proposed for a new empirical sea state bias (SSB model using information retrieved entirely from altimetric data. Nonparametric regression techniques are used, based on penalized smoothing splines adjusted to each predictor and then combined by a Generalized Additive Model. In addition to the significant wave height (SWH and wind speed (U10, a mediator parameter designed by the mean wave period derived from radar altimetry, has proven to improve the model performance in explaining some of the SSB variability, especially in swell ocean regions with medium-high SWH and low U10. A collinear analysis of scaled sea level anomalies (SLA variance differences shows conformity between the proposed model and the established SSB models. The new formulation aims to be a fast, reliable and flexible SSB model, in line with the well-settled SSB corrections, depending exclusively on altimetric information. The suggested method is computationally efficient and capable of generating a stable model with a small training dataset, a useful feature for forthcoming missions.

  14. Molecular epidemiology of group A streptococcus from pharyngeal isolates in Auckland, New Zealand, 2013. (United States)

    Williamson, Deborah A; Moreland, Nicole J; Carter, Philip; Upton, Arlo; Morgan, Julie; Proft, Thomas; Lennon, Diana; Baker, Michael G; Dunbar, Rod; Fraser, John D


    To describe the molecular epidemiology of emm types associated with circulating pharyngeal group A streptococcus (GAS) isolates in Auckland, New Zealand. GAS isolates were collected over a 10-day period from a community pathology provider in Auckland. PCR analysis and sequencing of the emm gene was performed at the Institute of Environmental Science and Research. A total of 52 emm types were identified from 278 GAS isolates. The three most common emm types were emm1, emm89 and emm12. Overall, the experimental 30-valent GAS M protein vaccine covered 19 / 52 (37%) of emm types in our study. Our study provides baseline data on the circulating pharyngeal GAS emm types in Auckland. Future clinical and molecular surveillance of GAS pharyngitis is essential in the context of ongoing GAS vaccine development.

  15. "La Lucha Continua": Becoming a Bilingual Teacher in the Era of Praxis II (United States)

    Hones, Donald F.; Aguilar, Nancy; Thao, Stacie


    This article provides portraits of two women on professional journeys to become bilingual teachers. Stacie Thao was born in Thailand. Nancy Aguilar was born in California, and spent some of her childhood in Mexico. Stacie's first language is Hmong, while Nancy's is Spanish. Each learned English in school, and each helped their immigrant parents…

  16. Autism, intellectual disability, and a challenge to our understanding of proxy consent. (United States)

    Graber, Abraham


    This paper focuses on a hypothetical case that represents an intervention request familiar to those who work with individuals with intellectual disability. Stacy has autism and moderate intellectual disability. Her parents have requested treatment for her hand flapping. Stacy is not competent to make her own treatment decisions; proxy consent is required. There are three primary justifications for proxy consent: the right to an open future, substituted judgment, and the best interest standard. The right to an open future justifies proxy consent on the assumption of future autonomy whereas substituted judgment justifies proxy consent via reference to past autonomy. Neither applies. Stacy has not been, nor will she be, competent to make her own treatment decisions. The best interest standard justifies proxy consent on the grounds of beneficence. It is unlikely that hand flapping harms Stacy. None of the three primary means of justifying proxy consent apply to Stacy's case.

  17. Enhanced Magnetic Model 2010 (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Enhanced Magnetic Model (EMM) extends to degree and order 720, resolving magnetic anomalies down to 56 km wavelength. The higher resolution of the EMM results in...

  18. Enhanced Magnetic Model 2015 (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Enhanced Magnetic Model (EMM) extends to degree and order 720, resolving magnetic anomalies down to 56 km wavelength. The higher resolution of the EMM results in...

  19. About Face

    Medline Plus

    Full Text Available ... sees the unspeakable. Rather than lose what she values most, she turns to treatment. Hear Stacy's story See all Up Close stories → Treatment Works Follow Veterans as they share their experiences with ...

  20. About Face

    Medline Plus

    Full Text Available ... Stacy's story See all Up Close stories → Treatment Works Follow Veterans as they share their experiences with two types of therapy that are proven to work. Learn more about Prolonged Exposure (PE) and Cognitive ...

  1. Status of criticality safety research at NUCEF

    Energy Technology Data Exchange (ETDEWEB)

    Nakajima, Ken [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment


    Two critical facilities, named STACY (Static Experiment Critical Facility) and TRACY (Transient Experiment Critical Facility), at the Nuclear Fuel Cycle Safety Engineering Research Facility (NUCEF) started their hot operations in 1995. Since then, basic experimental data for criticality safety research have been accumulated using STACY, and supercritical experiments for the study of criticality accident in a reprocessing plant have been performed using TRACY. In this paper, the outline of those critical facilities and the main results of TRACY experiments are presented. (author)

  2. ‘China: the empire of things’: Jason Steuber and Nick Pearce, Original Intentions: Essays on the Production, Reproduction, and Interpretation in the Arts of China, Gainesville, FL: University of Florida Press 2012

    Directory of Open Access Journals (Sweden)

    Michele Matteini


    Full Text Available Original Intentions: Essays on the Production, Reproduction, and Interpretation in the Arts of China is a collection of studies on the creation, circulation, and reception of three-dimensional objects from the Bronze Age to the modern times. This review concentrates on the volume’s methodological approach to and conceptual framing of issues like authenticity, and originality. The essay brings the volume and individual essays in relation to ongoing debates on materiality and making in the fields of Chinese and Western art, arguing for the possibility of a cross-cultural history of the material world.

  3. Global Gravity from Satellite Altimetry (Geosat, ERS-1, Envisat, Jason-1, and CryoSat-2) from 2010-01-01 to 2014-12-31 (NCEI Accession 0150966) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Gravity models are powerful tools for mapping tectonic structures, especially in the deep ocean basins where the topography remains unmapped by ships or is buried by...

  4. Molecular epidemiology, antimicrobial susceptibilities and resistance mechanisms of Streptococcus pyogenes isolates resistant to erythromycin and tetracycline in Spain (1994–2006

    Directory of Open Access Journals (Sweden)

    Rubio-López Virginia


    Full Text Available Abstract Background Group A Streptococcus (GAS causes human diseases ranging in severity from uncomplicated pharyngitis to life-threatening necrotizing fasciitis and shows high rates of macrolide resistance in several countries. Our goal is to identify antimicrobial resistance in Spanish GAS isolates collected between 1994 and 2006 and to determine the molecular epidemiology (emm/T typing and PFGE and resistance mechanisms of those resistant to erythromycin and tetracycline. Results Two hundred ninety-five out of 898 isolates (32.8% were erythromycin resistant, with the predominance of emm4T4, emm75T25, and emm28T28, accounting the 67.1% of the 21 emm/T types. Spread of emm4T4, emm75T25 and emm28T28 resistant clones caused high rates of macrolide resistance. The distribution of the phenotypes was M (76.9%, cMLSB (20.3%, iMLSB (2.7% with the involvement of the erythromycin resistance genes mef(A (89.5%, msr(D (81.7%, erm(B (37.3% and erm(A (35.9%. Sixty-one isolates were tetracycline resistant, with the main representation of the emm77T28 among 20 emm/T types. To note, the combination of tet(M and tet(O tetracycline resistance genes were similar to tet(M alone reaching values close to 40%. Resistance to both antibiotics was detected in 19 isolates of 7 emm/T types, being emm11T11 and the cMLSB phenotype the most frequent ones. erm(B and tet(M were present in almost all the strains, while erm(A, mef(A, msr(D and tet(O appeared in less than half of them. Conclusions Spanish GAS were highly resistant to macrolides meanwhile showed minor resistance rate to tetracycline. A remarkable correlation between antimicrobial resistance and emm/T type was noticed. Clonal spread of emm4T4, emm75T25 and emm28T28 was the main responsable for macrolide resistance where as that emm77T28 clones were it to tetraclycline resistance. A wide variety of macrolide resistance genes were responsible for three macrolide resistance phenotypes.

  5. Large remote manipulator operating and maintenance experience at IEM cell

    International Nuclear Information System (INIS)

    Hicks, D.F.; McGuinness, P.W.


    The Interim Examination and Maintenance (IEM) Cell at the Fast Flux Test Facility (FFTF) has two large Electro-Mechanical Manipulators (EMM's). These manipulators are used for cell operations (processing of reactor core components) as well as general cell maintenance. From our eleven years of operation and maintenance experience with these large EMM's, we have learned many lessons concerning manipulator design. This paper describes the IEM Cell EMM design features and discusses operating and maintenance experience at the IEM Cell

  6. PODAAC-J1SHA-NETGC (United States)

    National Aeronautics and Space Administration — These Sea Surface Height Anomalies (SSHA) are derived from the Jason-1 Geophysical Data Record (GDR) Geodetic Mission. Jason-1 is an altimetric mission whose...

  7. PODAAC-J1GPR-NCG0E (United States)

    National Aeronautics and Space Administration — These Sea Surface Height Anomalies (SSHA) are derived from the Jason-1 Geophysical Data Record (GDR) Geodetic Mission. Jason-1 is an altimetric mission whose...

  8. OW AVISO Sea-Surface Height & Niiler Climatology (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The dataset contains satellite-derived sea-surface height measurements collected by means of the TOPEX/Poseidon/ERS, JASON-1/Envisat, and Jason-2/Envisat satellite...

  9. PODAAC-ALTCY-TJ123 (United States)

    National Aeronautics and Space Administration — This dataset contains along track geo-referenced Sea Surface Height Anomalies (SSHA) from TOPEX/Poseidon, Jason-1 and OSTM/Jason-2 (depending on time period) merged...

  10. PODAAC-ALTCY-TJ124 (United States)

    National Aeronautics and Space Administration — This dataset contains along track geo-referenced Sea Surface Height Anomalies (SSHA) from TOPEX/Poseidon, Jason-1 and OSTM/Jason-2 (depending on time period) merged...

  11. PODAAC-ALTTS-TJ122 (United States)

    National Aeronautics and Space Administration — This dataset contains along track geo-referenced Sea Surface Height Anomalies (SSHA) from TOPEX/Poseidon, Jason-1 and OSTM/Jason-2 (depending on time period) merged...

  12. PODAAC-ALTTS-TJ123 (United States)

    National Aeronautics and Space Administration — This dataset contains along track geo-referenced Sea Surface Height Anomalies (SSHA) from TOPEX/Poseidon, Jason-1 and OSTM/Jason-2 (depending on time period) merged...

  13. PODAAC-ALTCY-TJ122 (United States)

    National Aeronautics and Space Administration — This dataset contains along track geo-referenced Sea Surface Height Anomalies (SSHA) from TOPEX/Poseidon, Jason-1 and OSTM/Jason-2 (depending on time period) merged...

  14. PODAAC-J1NRT-GSHAG (United States)

    National Aeronautics and Space Administration — These data are from the Jason-1 Geodetic Mission. The Jason-1 Near Real Time (NRT) Sea Surface Height Anomaly (SSHA) dataset contain SSHA that are available within 7...

  15. PODAAC-J1SHA-BIN00 (United States)

    National Aeronautics and Space Administration — The Jason-1 Sea Surface Height Anomaly product is generated from the Jason-1 Geophysical Data Record (J1 GDR). There are 127 orbits per cycle and each orbit has a...

  16. MERGED_TP_J1_OSTM_OST_ALL_V2:1 (United States)

    National Aeronautics and Space Administration — This dataset contains along track geo-referenced Sea Surface Height Anomalies (SSHA) from TOPEX/Poseidon, Jason-1 and OSTM/Jason-2 (depending on time period) merged...

  17. PODAAC-J1SHA-NETCC (United States)

    National Aeronautics and Space Administration — The SSHA are derived from the Jason-1 GDR. The instruments on Jason-1 make direct observations of the following quantities: altimeter range, significant wave height,...

  18. PODAAC-ALTTS-TJ121 (United States)

    National Aeronautics and Space Administration — This product contains along track gridded Sea Surface Height Anomalies (SSHA) from TOPEX/Poseidon, Jason-1 and OSTM/Jason-2 (depending on time period), with biases...

  19. MERGED_TP_J1_OSTM_OST_CYCLES_V2:1 (United States)

    National Aeronautics and Space Administration — This dataset contains along track geo-referenced Sea Surface Height Anomalies (SSHA) from TOPEX/Poseidon, Jason-1 and OSTM/Jason-2 (depending on time period) merged...

  20. M or M-like protein gene polymorphisms in human group G streptococci. (United States)

    Schnitzler, N; Podbielski, A; Baumgarten, G; Mignon, M; Kaufhold, A


    Many group G streptococci (GGS) isolated from infected humans (but not from animal sources) express M or M-like proteins with biological, immunochemical, and genetic features similar to those of group A streptococci (GAS). To further elucidate the recently proposed M-like protein gene (emmL gene) polymorphisms in GGS, Southern blots of genomic DNAs from 38 epidemiologically unrelated GGS strains isolated from human specimens and 12 GGS strains recovered from animal sources were hybridized with oligonucleotide probes designed to specifically detect GAS M class I and M class II M protein (emm) genes. All human-associated GGS strains showed DNA homology to the GAS M class I emm gene probe, whereas no hybridization was found with DNA from any of the animal-associated strains. The emmL genes from all human isolates were amplified by PCR, and the complete sequence of the emmL gene of the Rebecca Lancefield grouping strain D166B was determined. Again, this gene exhibited the structural features typical for emm genes of M class I GAS. The 5' regions of the PCR-amplified emmL genes of the remaining 37 human GGS strains were sequenced. This region showed a sequence diversity similar to that known for GAS emm genes. When strains whose N-terminal emmL gene sequences showed a homology of > 95% were defined as belonging to one genetic type, 30 strains were segregated into six distinct genetic types, whereas the remaining 8 strains each exhibited a unique emmL gene sequence. A high degree of homology between the N-terminal emmL gene segments of six GGS strains and the corresponding regions of either the emm12 or the emm57 gene of GAS was found, suggesting a horizontal gene transfer between strains of these species of beta-hemolytic streptococci. Besides a further understanding of the evolution of GGS emmL genes, the observed emmL gene polymorphisms in GGS could provide the basis for a molecular subspecies delineation of strains and offers the potential of typing GGS for

  1. NATO’s Preparedness for Cyberwar (United States)


    13 G. JASON HEALEY AND LEENDERT VAN BOCHOVEN ..................14 H. JASON HEALEY AND KLARA TOTHOVA JORDAN ....................15 I. JAMIE...initiatives and operational approaches to cyber stability make his work an invaluable contribution to the cyber policy debate.35 G. JASON HEALEY AND...LEENDERT VAN BOCHOVEN In “Strategic Cyber Early Warning: A Phased Adaptive Approach for NATO,” Jason Healey and Leendert van Bochoven contend that NATO

  2. Nii, nagu oli, seal, kus oli / Heili Sibrits

    Index Scriptorium Estoniae

    Sibrits, Heili, 1977-


    Arvustus: Goodwin, Jason. Janitšaride puu : [romaan] / inglise keelest tõlkinud Juhan Habicht. Tallinn : Varrak, 2006 ; Goodwin, Jason. Maokivi : [kriminaalromaan] / inglise keelest tõlkinud Juhan Habicht. Tallinn : Varrak, 2008 ; Goodwin, Jason. Bellini kaart / inglise keelest tõlkinud Juhan Habicht. Tallinn : Varrak, 2010

  3. The Invisible Student: Understanding Social Identity Construction within Performing Ensembles (United States)

    Hourigan, Ryan M.


    This article was taken from a qualitative case study about Jason, a child who suffered from traumatic brain injury syndrome. This research focused on interactions among Jason, his classmates, his band director, his parents, and his school district. Jason encountered many challenges as a child with special needs in band. The purpose of this article…

  4. Molecular Characteristics of Erythromycin-Resistant Streptococcus pyogenes Strains Isolated from Children Patients in Tunis, Tunisia. (United States)

    Ksia, Sonia; Smaoui, Hanen; Hraoui, Manel; Bouafsoun, Aida; Boutiba-Ben Boubaker, Ihem; Kechrid, Amel


    The aims of our study were to characterize phenotypically and genotypically erythromycin-resistant Streptococcus pyogenes or group A streptococci (ERGAS) isolates, to evaluate macrolide resistance and to analyze the association between emm types and virulence factors. Included in this study were all ERGAS strains isolated from 2000 to 2013 at the Children's hospital of Tunis. Antimicrobial susceptibility was performed according to the CA-SFM guidelines. Macrolide resistance genes were revealed by polymerase chain reaction (PCR) method. Virulence factor genes (pyrogenic exotoxin genes and superantigen gene) were detected by PCR, and the emm types were defined by the sequencing of the variable 5' end of the emm gene. Among the 289 GAS isolates collected, 15 (5.2%) were resistant to erythromycin; 7 of the strains were assigned to the cMLS B phenotype (46.6%); 5 harbored ermB gene alone (33.3%); and 2 strains coharbored ermB and mefA (13.3%). The remaining (53.4%) were assigned to the M phenotype and harbored the mefA gene. The frequency of detection of each toxin gene among ERGAS was 13.4% for speA (2 strains), 53.4% for speC (8 strains), and 13.4% for ssa (2 strains). Emm types 1, 58, 11, and 78 were the most frequent among ERGAS strains. The distribution of the cMLS B and M phenotypes changed over the period of investigation with a decrement of cMLS B phenotype and ermB gene that predominated between 2000 and 2006 and an increase of M phenotype and mefA gene between 2007 and 2013, but this difference was nonstatistically significant because of the low number of resistant strains. Emm types 1, 58, and 4 were only present among strains assigned to the M phenotype. However strains assigned to the cMLS B phenotype were associated to emm11, emm22, emm28, emm78, or emm76. There was diversity in emm distribution in ERGAS between the two study periods. There was diversity in emm distribution among ERGAS particularly in 2000-2006. Indeed, from 2000 to 2006, the 6 ERGAS

  5. evaluation of job performance of village extension agents in lagos ...

    African Journals Online (AJOL)


    Sole (2003) observed that inter-group conflict exist between two different groups in the form of ... destroyed (Nonli, 1989). According to Emme and Emme (1997), traders at the various market centers at Warri ... Many of the traders could not get back to the markets to continue with their trading because they could not raise ...

  6. Using Eye Movements to Model the Sequence of Text-Picture Processing for Multimedia Comprehension (United States)

    Mason, L.; Scheiter, K.; Tornatora, M. C.


    This study used eye movement modeling examples (EMME) to support students' integrative processing of verbal and graphical information during the reading of an illustrated text. EMME consists of a replay of eye movements of a model superimposed onto the materials that are processed for accomplishing the task. Specifically, the study investigated…

  7. Learning to See: Guiding Students' Attention via a Model's Eye Movements Fosters Learning (United States)

    Jarodzka, Halszka; van Gog, Tamara; Dorr, Michael; Scheiter, Katharina; Gerjets, Peter


    This study investigated how to teach perceptual tasks, that is, classifying fish locomotion, through eye movement modeling examples (EMME). EMME consisted of a replay of eye movements of a didactically behaving domain expert (model), which had been recorded while he executed the task, superimposed onto the video stimulus. Seventy-five students…

  8. Showing a model's eye movements in examples does not improve learning of problem-solving tasks

    NARCIS (Netherlands)

    van Marlen, Tim; van Wermeskerken, Margot; Jarodzka, Halszka; van Gog, Tamara


    Eye movement modeling examples (EMME) are demonstrations of a computer-based task by a human model (e.g., a teacher), with the model's eye movements superimposed on the task to guide learners' attention. EMME have been shown to enhance learning of perceptual classification tasks; however, it is an

  9. A Quality Framework for Continuous Improvement of e-Learning: The e-Learning Maturity Model (United States)

    Marshall, Stephen


    The E-Learning Maturity Model (eMM) is a quality improvement framework designed to help institutional leaders assess their institution's e-learning maturity. This paper reviews the eMM, drawing on examples of assessments conducted in New Zealand, Australia, the UK and the USA to show how it helps institutional leaders assess and compare their…

  10. Characterization of levofloxacin non-susceptible clinical Streptococcus pyogenes isolated in the central part of Italy. (United States)

    Petrelli, D; Di Luca, M C; Prenna, M; Bernaschi, P; Repetto, A; Vitali, L A


    We investigated the prevalence, genetics, and clonality of fluoroquinolone non-susceptible isolates of Streptococcus pyogenes in the central part of Italy. S. pyogenes strains (n = 197) were isolated during 2012 from patients with tonsillopharyngitis, skin, wound or invasive infections and screened for fluoroquinolone non-susceptibility (resistance to norfloxacin and levofloxacin minimum inhibitory concentration (MIC) = 2 mg/L) following EUCAST guidelines. First-step topoisomerase parC and gyrA substitutions were investigated using sequencing analysis. Clonality was determined by pulsed field gel electrophoresis (PFGE; SmaI digestion) and by emm typing. The fluoroquinolone non-susceptible phenotype was identified in 18 isolates (9.1 %) and correlated with mutations in parC, but not in gyrA, the most frequent leading to substitution of the serine at position 79 with an alanine. Most of the fluoroquinolone non-susceptible isolates belonged to the emm-type 6, even if other emm-types were also represented (emm75, emm89, and emm2). A significant level of association was measured between PFGE and both emm type and substitutions in parC. The prevalence of fluoroquinolone non-susceptible Streptococcus pyogenes isolates in Italy is of concern and, although the well-known emm type 6 is dominant, other types are appearing and spreading.

  11. Molecular epidemiological characteristics of Streptococcus pyogenes strains involved in an outbreak of scarlet fever in China, 2011. (United States)

    You, Yuan Hai; Song, Yan Yan; Yan, Xiao Mei; Wang, Hai Bin; Zhang, Meng Han; Tao, Xiao Xia; Li, Lei Lei; Zhang, Yu Xin; Jiang, Xi Hong; Zhang, Bing Hua; Zhou, Hao; Xiao, Di; Jin, Lian Mei; Feng, Zi Jian; Luo, Feng Ji; Zhang, Jian Zhong


    To investigate molecular characterization of streptococcus pyogenes isolates involved in an outbreak of scarlet fever in China in 2011. Seventy-four Streptococcal pyogenes involved in an outbreak of scarlet fever were isolated from pediatric patients in the areas with high incidence in China from May to August of 2011. Emm genotyping, pulsed-field gel electrophoresis (PFGE), superantigen (SAg) genes and antimicrobial susceptibility profiling were analyzed for these isolates. A total of 4 different emm types were identified. Emm12 was the most prevalent type which contained four predominating PFGE patterns corresponding to four different virulence and superantigen profiles. Emm12 (79.7%) and emm1 (14.9%) accounted for approximately 94% of all the isolates. The speA gene was all negative in emm12 isolates and positive in emm1 isolates. All strains were resistant to erythromycin, and 89.4% of them were resistant to erythromycin, tracycline, and clindamycin simultaneously. Several highly diversified clones with a high macrolide resistance rate comprise a predominant proportion of circulating strains, though no new emm type was found in this outbreak. The data provide a baseline for further surveillance of scarlet fever, which may contribute to the explanation of the outbreak and development of a GAS vaccine in China. Copyright © 2013 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.

  12. Association of the shuffling of Streptococcus pyogenes clones and the fluctuation of scarlet fever cases between 2000 and 2006 in central Taiwan

    Directory of Open Access Journals (Sweden)

    Wang Wan-Ling


    Full Text Available Abstract Background The number of scarlet fever occurrences reported between 2000 and 2006 fluctuated considerably in central Taiwan and throughout the nation. Isolates of Streptococcus pyogenes were collected from scarlet fever patients in central Taiwan and were characterized by emm sequencing and a standardized pulsed-field gel electrophoresis (PFGE method. National weekly report data were collected for investigating epidemiological trends. Results A total of 23 emm types were identified in 1,218 S. pyogenes isolates. The five most prevalent emm types were emm12 (50.4%, emm4 (23.2%, emm1 (16.4%, emm6 (3.8% and emm22 (3.0%. PFGE analysis with SmaI suggested that, with a few exceptions, strains with a common emm type belonged to the same clone. There were two large emm12 clones, one with DNA resistant to cleavage by SmaI. Each prevalent emm clone had major PFGE strain(s and many minor strains. Most of the minor strains emerged in the population and disappeared soon after. Even some major strains remained prevalent for only 2–3 years before declining. The large fluctuation of scarlet fever cases between 2000 and 2006 was associated with the shuffling of six prevalent emm clones. In 2003, the dramatic drop in scarlet fever cases in central Taiwan and throughout the whole country was associated with the occurrence of a severe acute respiratory syndrome (SARS outbreak that occurred between late-February and mid-June in Taiwan. Conclusion The occurrences of scarlet fever in central Taiwan in 2000–2006 were primarily caused by five emm types, which accounted for 96.8% of the isolates collected. Most of the S. pyogenes strains (as defined by PFGE genotypes emerged and lasted for only a few years. The fluctuation in the number of scarlet fever cases during the seven years can be primarily attributed to the shuffling of six prevalent emm clones and to the SARS outbreak in 2003.

  13. The Emirates Mars Mission Science Data Center (United States)

    Craft, James; Hammadi, Omran Al; DeWolfe, Alexandria; Staley, Bryan; Schafer, Corey; Pankratz, Chris


    The Emirates Mars Mission (EMM), led by the Mohammed Bin Rashid Space Center (MBRSC) in Dubai, United Arab Emirates, is expected to arrive at Mars in January 2021. The EMM Science Data Center (SDC) is to be developed as a joint effort between MBRSC and the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP). The EMM SDC is responsible for the production, management, distribution, and archiving of science data collected from the three instruments on board the Hope spacecraft. With the respective SDC teams on opposite sides of the world evolutionary techniques and cloud-based technologies are being utilized in the development of the EMM SDC. This presentation will provide a top down view of the EMM SDC, summarizing the cloud-based technologies being implemented in the design, as well as the tools, best practices, and lessons learned for software development and management in a geographically distributed team.

  14. Editorial

    Directory of Open Access Journals (Sweden)

    The Editors


    Full Text Available This issue of Higher Learning Research Communications (HLRC features research focused on faculty development from scholars across both sides of the Atlantic. The opening piece, Enhancing faculty performance through coaching: Targeted, individualized support, describes the culture within a US-based higher education institution, where emphasis is given to supporting faculty. One of their latest approaches has been to implement coaching as a means for professional development, with positive results. Promoting critical thinking skills has always been a challenge for higher education professionals. Different models and techniques have been researched and described in different contexts. And, as higher education makes its way into the 21st century, developing critical thinking skills in online learning environments can prove to be an even bigger challenge. Laura A. Schindler and Gary J. Burkholder present a literature review related to instructional design and facilitation approaches that promote critical thinking in asynchronous online discussions (AODs across multiple cognitive constructs (cognitive domain, cognitive presence, knowledge construction, and perspective-taking. According to their review of the available literature, certain design approaches are effective for promoting critical thinking. Another 21st century challenge has been globalization, with higher education professionals being able to teach face-to-face and online across the globe. However, cultural differences and language barriers may present teaching and learning challenges. In the article, Communicative differences between domestic and foreign instructors, authors Narissra Punyanunt-Carter, Jason Wrench, Stacy L Carter, and Daniel Linden researched how students perceived their instructors, depending on whether they were local or foreign. Their findings may aid international faculty make a better transition into US-based campuses and classrooms. From Spain, research conducted by

  15. Characterization of Streptococcus pyogenes from Animal Clinical Specimens, Spain. (United States)

    Vela, Ana Isabel; Villalón, Pilar; Sáez-Nieto, Juan Antonio; Chacón, Gema; Domínguez, Lucas; Fernández-Garayzábal, José Francisco


    Streptococcus pyogenes appears to be almost exclusively restricted to humans, with few reports on isolation from animals. We provide a detailed characterization (emm typing, pulsed-field gel electrophoresis [PFGE], and multilocus sequence typing [MLST]) of 15 S. pyogenes isolates from animals associated with different clinical backgrounds. We also investigated erythromycin resistance mechanisms and phenotypes and virulence genes. We observed 2 emm types: emm12 (11 isolates) and emm77 (4 isolates). Similarly, we observed 2 genetic linages, sequence type (ST) 26 and ST63. Most isolates exhibited the M macrolide resistance phenotype and the mefA/ermB genotype. Isolates were grouped into 2 clones on the basis of emm-MLST-PFGE-virulence gene profile combinations: clone 1, characterized by the combined genotype emm12-ST36-pulsotype A-speG; and clone 2, characterized by the genotype emm77-ST63-pulsotype B-speC. Our results do not show conclusively that animals may represent a new reservoir of S. pyogenes but indicate the ability of human-derived S. pyogenes isolates to colonize and infect animals.

  16. Highly virulent M1 Streptococcus pyogenes isolates resistant to clindamycin. (United States)

    Plainvert, C; Martin, C; Loubinoux, J; Touak, G; Dmytruk, N; Collobert, G; Fouet, A; Ploy, M-C; Poyart, C


    Emm1-type group A Streptococcus (GAS), or Streptococcus pyogenes, is mostly responsible for invasive infections such as necrotizing fasciitis (NF) and streptococcal toxic shock syndrome (STSS). The recommended treatment of severe invasive GAS infections is a combination of clindamycin and penicillin. Until 2012, almost all emm1 isolates were susceptible to clindamycin. We aimed to identify the phenotypic and genotypic characteristics of emm1 GAS clone resistant to clindamycin. GAS strains were characterized by emm sequence typing, detection of genes encoding pyrogenic exotoxins or superantigens. Cluster analysis was performed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). Antibiotic susceptibility was assessed using disk diffusion and resistance genes were detected by PCR. A total of 1321 GAS invasive isolates were analyzed between January 2011 and December 2012. The overall number of invasive isolates resistant to clindamycin was 52 (3.9%); seven of them were emm1 isolates. All isolates had the same genomic markers: macrolide resistance due to the presence of the erm(B) gene, emm subtype 1.0, the same toxin or superantigen profile, PFGE pattern and sequence type. This is the first description of highly virulent GAS emm1 isolates resistant to clindamycin in France. This article strengthens the need for monitoring the epidemiology of invasive GAS strains as they could lead to changes in treatment guidelines. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  17. Kuidas lennates kirjutada / Marko Tamm

    Index Scriptorium Estoniae

    Tamm, Marko


    Arvustus: Saint-Exupéry, Antoine de. Lõuna postilennuk : [romaan] / prantsuse keelest tõlkinud Merike Riives ; Inimeste maa : [romaan] / prantsuse keelest tõlkinud Merike Riives ja Maria Hange. [Tallinn] : Varrak, 2003; Schiff, Stacy. Antoine de Saint-Exupéry : [prantsuse kirjanik : 1900-1944] / tõlkinud [ja eessõna:] Lia Rajandi. [Tallinn] : Varrak, 2003

  18. Effect of oxygen deficiency on the magnetic field-dependent entropy ...

    Indian Academy of Sciences (India)

    there is a broadening of transition curve. Further, in the presence of magnetic field an additional broadening is observed for the transition curve which they have accounted due to the anisotropy of the ..... [4] N E Phillips, R A Fisher, S E Lacy, C Marcenat, J A Olsen, W K Ham, A M Stacy, J E Gordon and M L Tan, Physica ...

  19. Human Dimensions of Strategic Leadership: A Selected Bibliography (United States)


    Dalai Lama XIV. The Leader’s Way: The Art of Making the Right Decisions in Our Careers, Our Companies, and the World at Large. New York: Broadway...Officers." Military Review 88 (September-October 2008): 77-83. ProQuest Furst, Stacie, and Martha Reeves. "Queens of the Hill: Creative Destruction

  20. 977-IJBCS-Article-Dr Madjelia Some

    African Journals Online (AJOL)


    1998; Osunkoya, 1999), and behaviour of pollinators (House, 1992; Stacy et al., 1996). In addition to this, human ... on the sex ratio, reproductive success and spatial patterns of dioecious plants (Mack,. 1997; Ollerton and Lack, ..... birds and introduced honeybees. Biological Conservation, 15: 1645-1655. Gross CL. 2001.

  1. Criticality safety (prospect of study in NUCEF)

    International Nuclear Information System (INIS)

    Itagaki, Masafumi


    Experimental studies of criticality safety are under way using STACY and TRACY in NUCEF. Collection of fundamental data on criticality in a solution system is undergoing with STACY to confirm that the likelihood of criticality safety in the system constructed on the assumption of apparatuses in a reprocessing plant is enough large. Whereas some experiments simulating criticality accidents in a reprocessing plant using TRACY were designed to investigate the behaviors of fuel solution and radioactive matters in order to clarify whether it is possible to safely shut them in the facility even if a critical accident occurs. Both STACY and TRACY reached the criticality in 1995. Up to now a series of criticality experiments have been done using STACY with a core tank φ60 cm and the first periodical examination is now under way. On the other hand, we have a plan using TRACY to investigate the behaviors of nuclear heat solution at a criticality accident, and the releasing, transfer and deposition of radioactive materials. After reaching the criticality for the first, the performance verification test has been conducted. The full-scale study using TRACY is planned to begin in the second half of 1996. (M.N.)

  2. Down Syndrome: Co-Occuring Conditions (United States)

    Become an All-Star with NDSS & Zac Stacy! Learn more ! Skip to content Toggle navigation Home Our Story Mission Say Hello to Our ... a part of the 200+ advocates on the hill meeting with elected officials was inspiring and powerful. ...

  3. About Face

    Medline Plus

    Full Text Available ... sees the unspeakable. Rather than lose what she values most, she turns to treatment. Hear Stacy's story See all Up Close stories → Treatment Works Follow Veterans as they share their experiences with two types of therapy that are proven to work. Learn ...

  4. 76 FR 41791 - Environmental Impacts Statements; Notice of Availability (United States)


    .... Crabtree, PhD 727-824-5305. EIS No. 20110218, Final EIS, BPA, 00, Big Eddy-Knight Transmission Project, Proposal to Construct, Operate, and Maintain a 27-28 mile long 500-Kilovolt Transmission Line using a..., Wait Period Ends: 08/15/2011, Contact: Stacy Mason 503-230-5455. EIS No. 20110219, Final EIS, FTA, WA...

  5. Putting Knowledge to Work: Collaborating, Influencing and Learning ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Stacie Travers is Director of International Projects and Education at Tourism HR Canada, an Ottawa-based non-profit. Previously, she managed international mobility and award programmes with the Canadian Bureau for International Education and the International Development Research Centre, respectively. She holds ...

  6. What Do Trainers Need to Know to Train Higher-Order Thinking Skills (United States)


    Chris Wehmeier, CW5 Stacy McNeil, and COL Jim Payne for their interest in and ongoing support of this research. Finally, this research is in memory ...Committee on Measuring Human Capabilities: Performance Potential of Individuals and Collectives, Board on Behavioral, Cognitive, and Sensory Sciences

  7. Airpower Projection in the Anti-Access/Area Denial Environment: Dispersed Operations (United States)


    construct and the political and military threats to assured access for land based fighter aircraft power projection capabilities. 3 Pettyjohn and Vick , The...Stacie L and Alan J. Vick . The Posture Triangle: A New Framework for U.S. Air Force Global Presence. Santa Monica, CA: RAND Corporation, 2013. Schanz

  8. The Corruption of a Research Design: A Case Study of a Curriculum Innovation Project. (United States)

    Cline, Hugh F.; Mandinach, Ellen B.

    This chapter describes the corruption of research design and explains why and how a computer-based curriculum innovation project was transformed from a quasi-experimental design to a comparative case study. The first section introduces the Systems Thinking and Curriculum Innovation Network (STACI) that examined the impact of technology on teaching…

  9. Applying the Theoretical Domains Framework to identify barriers and targeted interventions to enhance nurses' use of electronic medication management systems in two Australian hospitals. (United States)

    Debono, Deborah; Taylor, Natalie; Lipworth, Wendy; Greenfield, David; Travaglia, Joanne; Black, Deborah; Braithwaite, Jeffrey


    Medication errors harm hospitalised patients and increase health care costs. Electronic Medication Management Systems (EMMS) have been shown to reduce medication errors. However, nurses do not always use EMMS as intended, largely because implementation of such patient safety strategies requires clinicians to change their existing practices, routines and behaviour. This study uses the Theoretical Domains Framework (TDF) to identify barriers and targeted interventions to enhance nurses' appropriate use of EMMS in two Australian hospitals. This qualitative study draws on in-depth interviews with 19 acute care nurses who used EMMS. A convenience sampling approach was used. Nurses working on the study units (N = 6) in two hospitals were invited to participate if available during the data collection period. Interviews inductively explored nurses' experiences of using EMMS (step 1). Data were analysed using the TDF to identify theory-derived barriers to nurses' appropriate use of EMMS (step 2). Relevant behaviour change techniques (BCTs) were identified to overcome key barriers to using EMMS (step 3) followed by the identification of potential literature-informed targeted intervention strategies to operationalise the identified BCTs (step 4). Barriers to nurses' use of EMMS in acute care were represented by nine domains of the TDF. Two closely linked domains emerged as major barriers to EMMS use: Environmental Context and Resources (availability and properties of computers on wheels (COWs); technology characteristics; specific contexts; competing demands and time pressure) and Social/Professional Role and Identity (conflict between using EMMS appropriately and executing behaviours critical to nurses' professional role and identity). The study identified three potential BCTs to address the Environmental Context and Resources domain barrier: adding objects to the environment; restructuring the physical environment; and prompts and cues. Seven BCTs to address Social

  10. The Emirates Space Data Center, a PDS4-Compliant Data Archive (United States)

    DeWolfe, A. W.; Al Hammadi, O.; Amiri, S.


    As part of the UAE's Emirates Mars Mission (EMM), we are constructing a data archive to preserve and distribute science data from this and future missions. The archive will be publicly accessible and will provide access to Level 2 and 3 science data products from EMM, as well as ancillary data such as SPICE kernels and mission event timelines. As a member of the International Planetary Data Alliance (IPDA), the UAE has committed to making its archive PDS4-compatible, and maintaining the archive beyond the end of the mission. EMM is scheduled to begin collecting science data in spring 2021, and the archive is expected to begin releasing data in September 2021.

  11. Calculation of the Fission Product Release for the HTR-10 based on its Operation History

    International Nuclear Information System (INIS)

    Xhonneux, A.; Druska, C.; Struth, S.; Allelein, H.-J.


    Since the first criticality of the HTR-10 test reactor in 2000, a rather complex operation history was performed. As the HTR-10 is the only pebble bed reactor in operation today delivering experimental data for HTR simulation codes, an attempt was made to simulate the whole reactor operation up to the presence. Special emphasis was put on the fission product release behaviour as it is an important safety aspect of such a reactor. The operation history has to be simulated with respect to the neutronics, fluid mechanics and depletion to get a detailed knowledge about the time-dependent nuclide inventory. In this paper we report about such a simulation with VSOP 99/11 and our new fission product release code STACY. While STACY (Source Term Analysis Code System) so far was able to calculate the fission product release rates in case of an equilibrium core and during transients, it now can also be applied to running-in-phases. This coupling demonstrates a first step towards an HCP Prototype. Based on the published power histogram of the HTR-10 and additional information about the fuel loading and shuffling, a coupled neutronics, fluid dynamics and depletion calculation was performed. Special emphasis was put on the complex fuel-shuffling scheme within both VSOP and STACY. The simulations have shown that the HTR-10 up to now generated about 2580 MWd while reshuffling the core about 2.3 times. Within this paper, STACY results for the equilibrium core will be compared with FRESCO-II results being published by INET. Compared to these release rates, which are based on a few user defined life histories, in this new approach the fission product release rates of Ag-110m, Cs-137, Sr-90 and I-131 have been simulated for about 4000 tracer pebbles with STACY. For the calculation of the HTR-10 operation history time-dependent release rates are being presented as well. (author)

  12. Joint Force Quarterly (Issue 71, 4th Quarter, October 2013) (United States)


    122. 6 Greg Rattray, Chris Evans, and Jason Healey , “American Security in the Cyber Commons,” in Contested Commons: The Future of American Power video/2012/02/22/cyberdeterrence-cyberwar.html>. 16 Gregory Rattray and Jason Healey , “Cat- egorizing and Understanding...Multinational Airborne Forcible Entry Capability By John W. Nicholson, Jr., Jason W. Condrey, and Claude A. Lambert 14 Revisiting NATO’s Kosovo Air War

  13. Cyber War: The Next Frontier for NATO (United States)


    Jason Healey and Klara Tothova Jordan, “NATO’s Cyber Capabilities: Yesterday, Today, and Tomorrow,” Atlantic Council, August 29, 2014, http...resort when all else has failed. In their essay to NATO in the Atlantic Council: Issue Brief, Jason Healey and Leendert van Bochoven explain why an...its monitoring system, which is 179 Jason Healey and Leendert van Bochoven, “Strategic Cyber Early Warning: Phased Adapting Approach for NATO

  14. Acquisition Dominance: Why The Make - Buy Decision And Decentralization Are Essential For DoDs Information Technology Acquisitions And Operations (United States)


    belligerent nexus).” 42 Healey , Jason “The Five Futures of Cyber Conflict and Cooperation” The Atlantic Council of the United States 2011. Available at http...Failure. New York: Farrar, Straus and Giroux, 2011. Healey , Jason “The Five Futures of Cyber Conflict and Cooperation” The Atlantic Council of the...execution. 120 Jason M. Golaboski, Major, “DOD WEAPONS SYSTEMS ACQUISITION: A CYBER DISCONNECT” 14 December 2011 Air Command and Staff College, 18. 121

  15. Seeing the Forest from the Sky: Joint Airpower Through the Lens of Complex Systems Theory (United States)


    Dr. James Mulvenon,Frank Hoffman, Lt Col Kelly Martin (USAF), Oliver Fritz, Eric Sterner,Dr. Greg Rattray, Chris Evans, Jason Healey , Robert D...Sterner,Dr. Greg Rattray, Chris Evans, Jason Healey , Robert D. Kaplan. Contested Commons:The Future of American Power in a Multipolar World. Edited...Sorrells, Lieutenant Colonel Glen R. Downing, USAF, Major Paul J. Blakesley, British Army,Major David W. Pendall, US Army, Major Jason K. Walk

  16. Complete Genome Sequence of Streptococcus pyogenes Strain JMUB1235 Isolated from an Acute Phlegmonous Gastritis Patient


    Watanabe, Shinya; Sasahara, Teppei; Arai, Naoshi; Sasaki, Kazumasa; Aiba, Yoshifumi; Sato?o, Yusuke; Cui, Longzhu


    Acute phlegmonous gastritis is an uncommon endogenous bacterial gastritis presenting with a high mortality rate. Here, we report the complete genome sequence of an emm89 Streptococcus pyogenes strain, JMUB1235, which is the causative agent of acute phlegmonous gastritis.

  17. Modified effective medium model for gas hydrate bearing,clay-dominated sediments in the Krishna-Godavari Basin

    Digital Repository Service at National Institute of Oceanography (India)

    Sriram, G.; Dewangan, P.; Ramprasad, T.

    of unconsolidated marine sediments as well as with hydrate. In this paper, we study the friction-dependent effective medium model (EMM) to understand these grain interactions. The compressional (P) and shear (S) wave velocities of fluid saturated sediments...

  18. Expectation-Maximization-Maximization: A Feasible MLE Algorithm for the Three-Parameter Logistic Model Based on a Mixture Modeling Reformulation. (United States)

    Zheng, Chanjin; Meng, Xiangbin; Guo, Shaoyang; Liu, Zhengguang


    Stable maximum likelihood estimation (MLE) of item parameters in 3PLM with a modest sample size remains a challenge. The current study presents a mixture-modeling approach to 3PLM based on which a feasible Expectation-Maximization-Maximization (EMM) MLE algorithm is proposed. The simulation study indicates that EMM is comparable to the Bayesian EM in terms of bias and RMSE. EMM also produces smaller standard errors (SEs) than MMLE/EM. In order to further demonstrate the feasibility, the method has also been applied to two real-world data sets. The point estimates in EMM are close to those from the commercial programs, BILOG-MG and flexMIRT, but the SEs are smaller.

  19. Expectation-Maximization-Maximization: A Feasible MLE Algorithm for the Three-Parameter Logistic Model Based on a Mixture Modeling Reformulation

    Directory of Open Access Journals (Sweden)

    Chanjin Zheng


    Full Text Available Stable maximum likelihood estimation (MLE of item parameters in 3PLM with a modest sample size remains a challenge. The current study presents a mixture-modeling approach to 3PLM based on which a feasible Expectation-Maximization-Maximization (EMM MLE algorithm is proposed. The simulation study indicates that EMM is comparable to the Bayesian EM in terms of bias and RMSE. EMM also produces smaller standard errors (SEs than MMLE/EM. In order to further demonstrate the feasibility, the method has also been applied to two real-world data sets. The point estimates in EMM are close to those from the commercial programs, BILOG-MG and flexMIRT, but the SEs are smaller.

  20. Erkki Luuk kuulab eksprimentaalset ambient'i / Erkki Luuk

    Index Scriptorium Estoniae

    Luuk, Erkki, 1971-


    Heliplaatidest: Killy Dog Box "The Silent Light", Legion "Zodiac", Erinevad esinejad "Bip-Hop Generation vol 6", Jason Lescalleet "Matresslessness", Francisco Lopez / Steve Roden "Le Chemin du Paradis"

  1. Prevalence of Group A beta-haemolytic Streptococcus isolated from children with acute pharyngotonsillitis in Aden, Yemen. (United States)

    Ba-Saddik, I A; Munibari, A A; Alhilali, A M; Ismail, S M; Murshed, F M; Coulter, J B S; Cuevas, L E; Hart, C A; Brabin, B J; Parry, C M


    To estimate the prevalence of Group A beta-haemolytic streptococcus (GAS) and non-GAS infections among children with acute pharyngotonsillitis in Aden, Yemen, to evaluate the value of a rapid diagnostic test and the McIsaac score for patient management in this setting and to determine the occurrence of emm genotypes among a subset of GAS isolated from children with acute pharyngotonsillitis and a history of acute rheumatic fever (ARF) or rheumatic heart disease (RHD). Group A beta-haemolytic streptococcus infections in school-aged children with acute pharyngotonsillitis in Aden, Yemen, were diagnosed by a rapid GAS antigen detection test (RADT) and/or GAS culture from a throat swab. The RADT value and the McIsaac screening score for patient management were evaluated. The emm genotype of a subset of GAS isolates was determined. Group A beta-haemolytic streptococcus pharyngotonsillitis was diagnosed in 287/691 (41.5%; 95% CI 37.8-45.3) children. Group B, Group C and Group G beta-haemolytic streptococci were isolated from 4.3% children. The RADT had a sensitivity of 238/258 (92.2%) and specificity of 404/423 (95.5%) against GAS culture. A McIsaac score of ≥4 had a sensitivity of 93% and a specificity of 82% for confirmed GAS infection. The emm genotypes in 21 GAS isolates from children with pharyngitis and a history of ARF and confirmed RHD were emm87 (11), emm12 (6), emm28 (3) and emm5 (1). This study demonstrates a very high prevalence of GAS infections in Yemeni children and the value of the RADT and the McIsaac score in this setting. More extensive emm genotyping is necessary to understand the local epidemiology of circulating strains. © 2014 John Wiley & Sons Ltd.

  2. The change of macrolide resistance rates in group A Streptococcus isolates from children between 2002 and 2013 in Asahikawa city. (United States)

    Sakata, Hiroshi


    This study targeted patients in the Department of Pediatrics, Asahikawa Kosei Hospital, between January 2002 and December 2013. In patients suspected of having hemolytic streptococcal infection, Group A Streptococcus (GAS) strains isolated from a throat swab were examined for antimicrobial susceptibility testing. The MICs were measured by the broth microdilution method. The annual number of GAS strains examined for antimicrobial susceptibility testing ranged from 28 to 65 strains, for a total of 574 strains. Some of the isolates obtained from 2006 to 2009 and from 2011 to 2013 were analyzed to determine their emm types. An erythromycin (EM) resistant strain was not detected until 2004, but one EM-resistant strain appeared in 2005. Subsequently, EM-resistant strains rapidly increased, and 48 of 65 strains (73.8%) examined in 2009 were resistant. In 2010, the number of EM-resistant strains decreased to 12 of 36 strains (33.3%). However, it gradually increased afterwards, and 37 of 60 strains (61.7%) were resistant in 2013. Out of 574 strains examined, 184 exhibited EM-resistance, and the overall resistance rate was 31.9%. Partitioning the 124 strains examined between 2006 and 2008 according to emm types, only emm28 strains, which exhibited a high resistance rate, and emm12 strains demonstrated resistance. For the 142 strains examined between 2011 and 2013, the resistance rate of emm28 strains was similarly high; the resistance of emm12 strains significantly increased, and emm1 strains exhibited a high resistance rate. The number of emm types associated with the resistant strains increased. Copyright © 2015 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  3. Molecular epidemiology, antimicrobial susceptibility, and characterization of macrolide-resistant Streptococcus pyogenes in Japan. (United States)

    Tanaka, Yuhei; Gotoh, Kenji; Teramachi, Mariko; Ishimoto, Kazuhisa; Tsumura, Naoki; Shindou, Shizuo; Yamashita, Yushiro


    Here we report the molecular epidemiology of macrolide-resistant Streptococcus pyogenes (group A streptococci, GAS) isolated from children with pharyngotonsillitis between 2011 and 2013 in Japan. In 299 isolates, 124 (41.5%) isolates were macrolide-resistant. We characterized the isolates by emm typing, multilocus sequence typing (MLST), and pulsed-field gel electrophoresis (PFGE). Of 299 isolates, 124 (41.5%) were macrolide-resistant isolates, 76 (61.3%) possessed mefA and 46 (37.1%) possessed ermB. All 76 isolates with mefA possessed msrD. There were no isolates possessed ermTR in this study. Eight emm/MLST types were observed. The predominant type was emm1/ST28 (57 isolates, 46.0%), which possessed the mefA/msrD complex, presenting as the M phenotype. The second most predominant type was emm12/ST467, which possessed ermB, presenting as the cMLS B phenotype. Of the cMLS B phenotype isolates, types emm28/ST52 and emm12/ST36 had multiple genetic backgrounds. We found high proportions of macrolide-resistant GAS in the southwestern areas of Japan. Copyright © 2016 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  4. Creating a New Military Service: Historical Precedents (United States)


    networked military operations.186 186 Jason Healey, and Karl Grindal, eds. A Fierce Domain ...187 Healey, and Grindal, A Fierce Domain , 122. 188 Gregory W. Ball, Over, Not Through: The Air Force and...Historical Division, 1955. Grier, Peter. “The Force and Space.” Air Force Magazine, February 2001. Healey, Jason and Karl Grindal, eds. A Fierce Domain

  5. NATO’s Options for Defensive Cyber Against Non-State Actors (United States)


    newsroom/testimonies (accessed December 11, 2012) 20 Jason Healey , “Breakthrough or Just Broken? China and Russia’s UNGA Proposal on Cyber Norms,” New...See Margaret Rouse’s definition in SearchNetworking, (accessed February 12, 2013) 9 Jason

  6. Strategic Studies Quarterly. Volume 10, Number 2, Summer 2016 (United States)


    United States Cyber Command,” 11 March 2014, 29–30, 39. Ibid. 40. Jason Healey $4.71 million in Fiscal Year 2015 (Oestegaard). 128. Paul Scharre, “Preface,” in Directed-Energy Weapons: Promise and Prospects, Jason D. Ellis

  7. AFCYBER: Postured to Support Air Force and USCYBERCOM Cyber Needs? (United States)


    Jason Healey , “Claiming the Lost Cyber Heritage,” Strategic Studies Quarterly, Fall 2012, 12. 11 Secretary of the Air Force Michael W. Wynne and...Fall 2008), 10. 86 Ibid., 10; Jason Healey , “Claiming the Lost Cyber Heritage,” Strategic Studies Quarterly (Fall 2012), 16. 87 “Cyber Guardian

  8. Strategic Studies Quarterly. Volume 5, Number 1, Spring 2011 (United States)


    Cyberdeterrence and Cyberwar (Santa Monica, CA: RAND, 2009). 21. Greg Rattray, Chris Evans, and Jason Healey , “American Security in the Cyber Com- 74. Jason Sherman, “CENTCOM Eyes Blogs to Shape Opinion,”, 3 March

  9. Let Slip the Dogs of (CYBER) War: Progressing Towards a Warfighting U.S. Cyber Command (United States)


    485-552. Rattray, Gregory and Jason Healey . Categorizing and Understanding Offensive Cyber Capabilities and Their Use. Washington, DC: National...spent any time in a collegiate library: Gail N., Dawn J., Jeannemarie S., Jason G., Catrina W., and Kari A. Yes, Gail, I have burned my copy of

  10. Transitions Towards Operational Space-Based Ocean Observations: From Single Research Missions into Series and Constellations (United States)


    globalisation has definitely advantages in terms of meeting temporal and spatial requirements provided that timely open access to data is guaranteed and...the Jason-3 mission. Moreover, concept definition and agency cooperation have started for a series of missions beyond Jason-3. In the context of

  11. Online Journalism in Africa: Trends, Practices and Emerging

    DEFF Research Database (Denmark)

    Ngomba, Teke Jacob


    Review of: Online Journalism in Africa: Trends, Practices and Emerging Cultures' Hayes M. Mabweazara, Okoth Fred Mudhai, and Jason Whittaker (Eds) London and New York: Routledge, 2014.......Review of: Online Journalism in Africa: Trends, Practices and Emerging Cultures' Hayes M. Mabweazara, Okoth Fred Mudhai, and Jason Whittaker (Eds) London and New York: Routledge, 2014....

  12. Creating an Online Laboratory (United States)


    Jason, David Lazer, Brooke Foucault -Welles, Brian Keegan, Christoph Riedl, M. Scott Poole, and Jefferson Hoye. “Conducting Massively-Open Online...Ceyhun Karbeyaz, Katherine Ognyanova, Brooke Foucault Welles, Waleed Meleis , David Lazer. Validating a Citizen Science Model for Online Social and...Behavioral Experiments Using Volunteer Science, Social Psychology Quarterly (03 2015) Brian Keegan, Jason Radford, Brooke Foucault Welles, Christoph

  13. Ensuring U.S. Air Force Operations During Cyber Attacks Against Combat Support Systems: Guidance for Where to Focus Mitigation Efforts (United States)


    Harris, Scott Maruoka, and Jason Frye , Cyber Threat Metrics, Albuquerque, N.M.: Sandia National Laboratories, SAND2012-2427, 2012. 15 John D. Howard...Cynthia K. Veitch, John Michalski, J. Mark Harris, Scott Maruoka, and Jason Frye , Cyber Threat Metrics, Albuquerque, N.M.: Sandia National

  14. Coding Complete Genome for the Mogiana Tick Virus, a Jingmenvirus Isolated from Ticks in Brazil (United States)


    Miranda-Santosb, Gustavo Palaciosa and Jason T Ladner#a # Corresponding author: a Center for Genome Sciences , United...unsegmented viruses of the genus Flavivirus (1). Although the Jingmenvirus group has only recently been recognized, with the first virus descriptions

  15. 78 FR 23934 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company (United States)


    ... limited liability company, individually, with Stephen L. LaFrance, Jr., Little Rock, Arkansas, as the sole... Properties, LLC, a Missouri limited liability company, with Stephen L. LaFrance, Jr., Jason P. LaFrance, and... limited liability company, with Stephen L. LaFrance, Jr. and Jason P. LaFrance as managers, the Stephen L...

  16. "I've Had Conversations That Have Gone on for Hours": A Portrait of an Autistic Youth's Online Relationship Building (United States)

    Kist, William; Morgan, Kate


    This article examines what that immersion in virtual worlds has looked like for Jason (a pseudonym), a 21-year-old person diagnosed on the autism spectrum who has participated in virtual games since he was 12. Over the four years we have followed Jason, what has been noticeable is not only the increasing communication skills he has demonstrated,…

  17. Observing and Modelling the HighWater Level from Satellite Radar Altimetry During Tropical Cyclones

    DEFF Research Database (Denmark)

    Deng, Xiaoli; Gharineiat, Zahra; Andersen, Ole Baltazar


    that altimetry data can capture high water levels induced by Larry and Yasi through a careful re-processing and re-editing of the data. About 18 years of data from multi-satellite altimetry missions including TOPEX/Poseidon, Jason-1 and Jason-2, and seven tide gauges around the northern Australian coast...

  18. Caracterización molecular de Streptococcus pyogenes causantes de enfermedad invasora y síndrome de shock tóxico estreptocócico Molecular characterization of Streptococcus pyogenes from invasive disease and streptococcal toxic shock syndrome episodes

    Directory of Open Access Journals (Sweden)

    F. Traverso


    Full Text Available Streptococcus pyogenes es el agente causal de varias enfermedades comunes entre las que se incluyen la faringoamigdalitis, la escarlatina y el impétigo. Sin embargo, en las últimas décadas se ha registrado mundialmente un resurgimiento de casos de enfermedad invasora y síndrome de shock tóxico estreptocócico (SSTE. El propósito del presente trabajo fue estudiar la diversidad genética, los factores de virulencia (genes spe, sme, ssa y la sensibilidad a los antibióticos de 10 cepas de S. pyogenes causantes de enfermedad invasora y SSTE. Los aislamientos fueron recuperados de hemocultivos de pacientes internados en el Hospital Santamarina y en la Nueva Clínica Chacabuco (Tandil, Argentina entre diciembre de 2000 y abril de 2005. Predominaron 2 patrones de electroforesis en campo pulsante. El más frecuente comprendió 5 aislamientos del tipo emm1-T1, con perfil de toxinas speA, speB, speF, speG y smeZ. El segundo patrón más frecuente incluyó 2 aislamientos tipo emm3-TNT (speB, speF, speG. Estos dos tipos (emm1 y emm3 fueron los prevalentes en las infecciones invasoras. Las otras tres cepas correspondieron a los tipos emm49-TNT (speB, speC, speF, speG, emm75-T25 (speB, speF, speG y emm83-TNT (speB, speF, speG, ssa, smeZ. Se encontró diversidad genética entre las cepas aisladas, pero todos los aislamientos fueron sensibles a penicilina, cefotaxima, eritromicina, clindamicina, cloranfenicol, tetraciclina y rifampicina. Por tal motivo, aún es válido el tratamiento empírico con penicilina asociada a clindamicina.Streptococcus pyogenes causes a variety of common human diseases, including pharyngitis, scarlet fever and impetigo. Nevertheless, the past decades have witnessed a worldwide resurgence in invasive disease and streptococcal toxic shock syndrome (STSS. The objective of the present study is to evaluate the genetic diversity, virulence gene distribution (spe, sme and ssa genes and susceptibility pattern of 10 S. pyogenes isolates

  19. Importance of differentiating Mycobaterium bovis in tuberculous meningitis

    Directory of Open Access Journals (Sweden)

    Alejandra Gonzàlez-Duarte


    Full Text Available The aim of the article is to describe the principal findings among patients with M.tuberculosis and <em>M. bovis CNS infection. Mycoba - cterium tuberculosis is one of the most common infectious agents that cause death and neurological sequelae around the world. Most of the complications of CNS TB can be attributed to a delay in the diagnosis. Unfortu nately, there are no specific diagnostic tools to support an early diagnosis. Other prognostic factors different from delay in treatment have not been identified. Clinical, radiological and laboratory characteristics were analyzed retrospectively from the medical files of all the patients admitted with the diagnoses of tuberculosis. Of 215 patients admitted with systemic tuberculosis, 64 (30% had a neurological infection. Positive cultures were found in 54 (84% cases, 18 (33% in the CSF and the rest in other fluids or tissues. Adenosin deaminase (ADA enzyme determination was more sensitive than <em>M. tuberculosis PCR in the CSF for supporting an early diagnosis. In addition to a later clinical stage and treatment lag, positive CSF cultures (P=0.001 and the presence of <em>M. bovis (P=0.020 were prognostic factors for a worse outcome. Neither older age, the presence of tuberculomas versus meningeal enhancement, or HIV co-infection, was associated to a worse prognosis. The isolation of <em>M. bovis subspecies was more common that previously reported, and it was associated to the development of parenchymal lesions (P=0.032 when compared to <em>M. tuberculosis. In this study, positive CSF cultures for <em>M. tuberculosis and further identifying <em>M. bovis species were additional prognostic factors for worse outcome. Positive cultures in systemic fluids other than CSF, even when the patient had no obvious systemic manifestations, and ADA determination in the CSF were noteworthy diagnostic tools for the diagnosis.

  20. Population and Whole Genome Sequence Based Characterization of Invasive Group A Streptococci Recovered in the United States during 2015

    Directory of Open Access Journals (Sweden)

    Sopio Chochua


    Full Text Available Group A streptococci (GAS are genetically diverse. Determination of strain features can reveal associations with disease and resistance and assist in vaccine formulation. We employed whole-genome sequence (WGS-based characterization of 1,454 invasive GAS isolates recovered in 2015 by Active Bacterial Core Surveillance and performed conventional antimicrobial susceptibility testing. Predictions were made for genotype, GAS carbohydrate, antimicrobial resistance, surface proteins (M family, fibronectin binding, T, R28, secreted virulence proteins (Sda1, Sic, exotoxins, hyaluronate capsule, and an upregulated nga operon (encodes NADase and streptolysin O promoter (Pnga3. Sixty-four M protein gene (emm types were identified among 69 clonal complexes (CCs, including one CC of Streptococcus dysgalactiae subsp. equisimilis. emm types predicted the presence or absence of active sof determinants and were segregated into sof-positive or sof-negative genetic complexes. Only one “emm type switch” between strains was apparent. sof-negative strains showed a propensity to cause infections in the first quarter of the year, while sof+ strain infections were more likely in summer. Of 1,454 isolates, 808 (55.6% were Pnga3 positive and 637 (78.9% were accounted for by types emm1, emm89, and emm12. Theoretical coverage of a 30-valent M vaccine combined with an M-related protein (Mrp vaccine encompassed 98% of the isolates. WGS data predicted that 15.3, 13.8, 12.7, and 0.6% of the isolates were nonsusceptible to tetracycline, erythromycin plus clindamycin, erythromycin, and fluoroquinolones, respectively, with only 19 discordant phenotypic results. Close phylogenetic clustering of emm59 isolates was consistent with recent regional emergence. This study revealed strain traits informative for GAS disease incidence tracking, outbreak detection, vaccine strategy, and antimicrobial therapy.

  1. Iridescent Virus and Nosema ceranae Linked to Honeybee Colony Collapse Disorder (United States)


    Almond Board, American Beekeeping Federation, and the U.S. Army Medical Research and Material Command, Award Number W81XWH-04-C-0013; with data...Firth, Stacy Potter, and the many U.S. beekeepers who allowed us to sample their bees. Blank CONTENTS 1. INTRODUCTION 7 2. MATERIALS AND METHODS 7...migratory beekeeping businesses that exhibited signs of CCD. In all, six different sample sets were taken. Two were from migratory beekeeping businesses

  2. Injection of Retrograde Beads into the Nucleus Accumbens (NAc) and Medial Prefronral Cortex (mPFC) to Isolate Projection-Specific Neurons in the Ventral Tegmental Area (VTA)




    Authors: Jessica Walsh, Allyson Friedman, Dipesh Chaudhury, Barbara Juarez, Stacy Ku & Ming-Hu Han ### Abstract Retrograde dyes, such as lumafluors, have been used as tracers to visualize neurons that project to a specific target region. Injection of these dyes provides an important method in being able to understand the functional role of projection-specific neurons. Lumafluors can be directly injected into a target brain region of a mouse and dye positive cells from the projection ...

  3. Optogenetic manipulation of Ventral Tegmental Area (VTA) Neurons that project to the Nucleus Accumbens (NAc) and medial Prefrontal Cortex (mPFC)




    Authors: Jessica Walsh, Dipesh Chaudhury, Allyson Friedman, Barbara Juarez, Stacy Ku, Mary Kay Lobo & Ming-Hu Han ### Abstract Optogenetics has evolved to be a critical technique used to manipulate the firing activity of specific subsets of neurons. Through the use of specific firing parameters, it has become possible to control the behavior of freely moving animals. Here we have established a system to control projection pathway-specific neurons from a particular brain region through...

  4. Preventing Flu During Pregnancy (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts


    During the influenza season, pregnant women and infants under 6 months old are especially susceptible to severe complications from the flu. The seasonal flu vaccination is the best way to protect both mother and baby. In this podcast Dr. Stacie Greby discusses the importance of pregnant women receiving the flu vaccine.  Created: 9/26/2013 by MMWR.   Date Released: 9/26/2013.

  5. Accomplishment of 10-year research in NUCEF and future development. Criticality safety research

    International Nuclear Information System (INIS)

    Miyoshi, Yoshinori


    Since 1995, static and transient critical experiments on low enriched uranyl nitrate solution have been performed using two solution type criticality facilities, STACY and TRACY constructed in NUCEF. The obtained fundamental and systematic data on aqueous solution were used to validate the criticality safety calculation codes and to develop the transient analyses codes for criticality accident evaluation. This paper describes the outline of the criticality safety research conducted in NUCEF. (author)

  6. Present status of Japanese Criticality Safety Handbook

    International Nuclear Information System (INIS)

    Okuno, Hiroshi


    A draft of the second edition of Nuclear Criticality Safety Handbook has been finalized, and it is under examination by reviewing committee for JAERI Report. Working Group designated for revising the Japanese Criticality Safety Handbook, which is chaired by Prof. Yamane, is now preparing for 'Guide on Burnup Credit for Storage and Transport of Spent Nuclear Fuel' and second edition of 'Data Collection' part of Handbook. Activities related to revising the Handbook might give a hint for a future experiment at STACY. (author)

  7. Validating a Method for Enhanced Communications and Situational Awareness at the Incident Command Level (United States)


    along with Dick Bartlett and FBI Special Agent Steve Stacy for their strong endorsements for my application. I also wish to thank the Metro ...accessed December 2005. 38 According to Doug Hamilton, Executive Director of Metro Louisville Emergency Management Agency, in personal...VoIP telephony, wireless networking, and an Ethernet switch. That pricing does not include radio interoperability or a satellite terminal. • Cisco

  8. U.S. Security-Related Agreements in Force Since 1955: Introducing a New Database (United States)


    Britain and the United States governing use of land in Bermuda will terminate when Bermuda becomes independent, but a new agreement between the United...States and Bermuda will begin in that year (assuming that both parties agree to continue the relationship). In each case of a newly independent or...279. Pettyjohn, Stacie L., and Alan J. Vick, The Posture Triangle : A New Framework for U.S. Air Force Global Presence, Santa Monica, Calif.: RAND

  9. Evaluation and Validation (E&V) Team Public Report. Volume 2. (United States)


    Gilroy. Draft the compiler implementation dependencies for the Requirements Document. AI-3-7-85-39: Helen Romanowsky . Human/computer interfaces of...Way San Diego, Ca 92110 Stacy Reddan Helen Romanowsky Rockwell International 400 Collins Rd NE Cedar Rapids, lo 52498 Lt. Darlene Sabota Ray...McClellan AFB, CA 95652-5609 3990 Sherman St. San Diego, CA92110 Reilly, Paul Rohrer, Amos Data General EGG Westboro, MA Manassas, VA Romanowsky

  10. The Accidental Change Agent: Using the Air Force in the Process of Social Change (United States)


    Beckett , Chiaying Chien and Jerry Sollinger, The Status of Gender Integration in the Military: Analysis of Selected Occupations (Santa Monica, CA: RAND...Force (Force Management and Personnel), to Assistant Secretary of Defense (Force Management Policy), memorandum, 20 March 1996. 60 Harrell, Beckett ...Frank, Stacie Furia, George Lucas, Gary Packard, Tammy Schultz, Steven Samuels , and David Segal. One Year Out: An Assessment of DADT Repeal’s Impact

  11. Construction of new critical experiment facilities in JAERI

    International Nuclear Information System (INIS)

    Takeshita, Isao; Itahashi, Takayuki; Ogawa, Kazuhiko; Tonoike, Kotaro; Matsumura, Tatsuro; Miyoshi, Yoshinori; Nakajima, Ken; Izawa, Naoki


    Japan Atomic Energy Research Institute (JAERI) has promoted the experiment research program on criticality safety since early in 1980s and two types of new critical facilities, Static Experiment Critical Facility (STACY) and Transient Experiment Critical Facility (TRACY) were completed on 1994 in Nuclear Fuel Cycle Safety Engineering Research Facility (NUCEF) of JAERI Tokai Research Establishment. STACY was designed so as to obtain critical mass data of low enriched uranium and plutonium solution which is extensively handled in LWR fuel reprocessing plant. TRACY is the critical facility where critical accident phenomenon is demonstrated with low enriched uranium nitrate solution. For criticality safety experiments with both facilities, the Fuel Treatment System is attached to them, where composition and concentration of uranium and plutonium nitrate solutions are widely varied so as to obtain experiments data covering fuel solution conditions in reprocessing plant. Design performances of both critical facilities were confirmed through mock-up tests of important components and cold function tests. Hot function test has started since January of 1995 and some of the results on STACY are to be reported. (author)

  12. Identification and Characterization of Fluoroquinolone Non-susceptible Streptococcus pyogenes Clones Harboring Tetracycline and Macrolide Resistance in Shanghai, China (United States)

    Shen, Yinfang; Cai, Jiehao; Davies, Mark R.; Zhang, Chi; Gao, Kun; Qiao, Dan; Jiang, Haoqin; Yao, Weilei; Li, Yuefang; Zeng, Mei; Chen, Mingliang


    Streptococcus pyogenes, also known as group A Streptococcus (GAS), is one of the top 10 infectious causes of death worldwide. Macrolide and tetracycline resistant GAS has emerged as a major health concern in China coinciding with an ongoing scarlet fever epidemic. Furthermore, increasing rates of fluoroquinolone (FQ) non-susceptibility within GAS from geographical regions outside of China has also been reported. Fluoroquinolones are the third most commonly prescribed antibiotic in China and is an therapeutic alternative for multi-drug resistant GAS. The purpose of this study was to investigate the epidemiological and molecular features of GAS fluoroquinolone (FQ) non-susceptibility in Shanghai, China. GAS (n = 2,258) recovered between 2011 and 2016 from children and adults were tested for FQ-non-susceptibility. Efflux phenotype and mutations in parC, parE, gyrA, and gyrB were investigated and genetic relationships were determined by emm typing, pulsed-field gel electrophoresis and phylogenetic analysis. The frequency of GAS FQ-non-susceptibility was 1.3% (30/2,258), with the phenotype more prevalent in GAS isolated from adults (14.3%) than from children (1.2%). Eighty percent (24/30) of FQ-non-susceptible isolates were also resistant to both macrolides (ermB) and tetracycline (tetM) including the GAS sequence types emm12, emm6, emm11, and emm1. Genomic fingerprinting analysis of the 30 isolates revealed that non-susceptibility may arise in various genetic backgrounds even within a single emm type. No efflux phenotype was observed in FQ non-susceptible isolates, and molecular analysis of the quinolone resistance-determining regions (QRDRs) identified several sequence polymorphisms in ParC and ParE, and none in GyrA and GyrB. Expansion of this analysis to 152 publically available GAS whole genome sequences from Hong Kong predicted 7.9% (12/152) of Hong Kong isolates harbored a S79F ParC mutation, of which 66.7% (8/12) were macrolide and tetracycline resistant

  13. Identification and Characterization of Fluoroquinolone Non-susceptible Streptococcus pyogenes Clones Harboring Tetracycline and Macrolide Resistance in Shanghai, China

    Directory of Open Access Journals (Sweden)

    Yinfang Shen


    Full Text Available Streptococcus pyogenes, also known as group A Streptococcus (GAS, is one of the top 10 infectious causes of death worldwide. Macrolide and tetracycline resistant GAS has emerged as a major health concern in China coinciding with an ongoing scarlet fever epidemic. Furthermore, increasing rates of fluoroquinolone (FQ non-susceptibility within GAS from geographical regions outside of China has also been reported. Fluoroquinolones are the third most commonly prescribed antibiotic in China and is an therapeutic alternative for multi-drug resistant GAS. The purpose of this study was to investigate the epidemiological and molecular features of GAS fluoroquinolone (FQ non-susceptibility in Shanghai, China. GAS (n = 2,258 recovered between 2011 and 2016 from children and adults were tested for FQ-non-susceptibility. Efflux phenotype and mutations in parC, parE, gyrA, and gyrB were investigated and genetic relationships were determined by emm typing, pulsed-field gel electrophoresis and phylogenetic analysis. The frequency of GAS FQ-non-susceptibility was 1.3% (30/2,258, with the phenotype more prevalent in GAS isolated from adults (14.3% than from children (1.2%. Eighty percent (24/30 of FQ-non-susceptible isolates were also resistant to both macrolides (ermB and tetracycline (tetM including the GAS sequence types emm12, emm6, emm11, and emm1. Genomic fingerprinting analysis of the 30 isolates revealed that non-susceptibility may arise in various genetic backgrounds even within a single emm type. No efflux phenotype was observed in FQ non-susceptible isolates, and molecular analysis of the quinolone resistance-determining regions (QRDRs identified several sequence polymorphisms in ParC and ParE, and none in GyrA and GyrB. Expansion of this analysis to 152 publically available GAS whole genome sequences from Hong Kong predicted 7.9% (12/152 of Hong Kong isolates harbored a S79F ParC mutation, of which 66.7% (8/12 were macrolide and tetracycline resistant

  14. Molecular characterization and evaluation of the emerging antibiotic-resistant Streptococcus pyogenes from eastern India. (United States)

    Ray, Dipanwita; Saha, Somnath; Sinha, Sukanta; Pal, Nishith Kumar; Bhattacharya, Basudev


    Group A Streptococcus strains causing wide variety of diseases, recently became noticeable in eastern India, are not amenable to standard treatment protocol thus enhancing the possibility of disease morbidity by becoming antibiotic resistance. The association of Lancefield group A Streptococcal variation with degree of vir architectural diversity was evaluated using emm typing and restriction fragment length polymorphism analyses. The antibiotic sensitivity patterns were examined by modified Kirby-Bauer method of disk diffusion. Percentage calculations, 95% confidence interval and one-way ANOVA were used to assess differences in proportions. Our observations revealed 20 different emm types and 13 different HaeIII vir typing patterns. A 1.2 kb fragment was found in all HaeIII typing pattern. Fragments of 1.2 kb and 550 bp were conserved in majority of the isolates. HinfI digestion was found proficient in differentiating the strains of same vir typing patterns. Strong predominance of speC (85%) and speF (80%) genes have been observed encoding exotoxins production. 4 isolates were found to be erythromycin resistant and were of genotype emm49. High degree of tetracycline resistance was shown by 53.57% isolates which belonged to 12 different emm genotypes. These findings suggested that in addition to emm typing, sequential application of HaeIII and HinfI restriction enzymes in vir typing analysis is an effective tool for group A streptococcal molecular characterization associated with antibiotic resistance.

  15. Strategy to minimize the impact of the South Atlantic Anomaly effect on the DORIS station position estimation (United States)

    Capdeville, H.; Moreaux, G.; Lemoine, J. M.


    All the Ultra Stable Oscillators (USO) of DORIS satellites are more or less sensitive to the South Atlantic Anomaly (SAA) effect. For Jason-1 and SPOT-5 satellites, a corrective model has been developed and used for the realization of the ITRF2014. However, Jason-2 is also impacted, not at the same level as Jason-1 but strong enough to worsen the multi-satellite solution provided for ITRF2014 for the SAA stations. The last DORIS satellites are also impacted by the SAA effect, in particular Jason-3. Thanks to the extremely precise time-tagging of the T2L2 experiment on-board Jason-2, A. Belli and the GEOAZUR team managed to draw up a model that accurately represents the variations of Jason-2 USO's frequency. This model will be evaluated by analyzing its impact on the position estimation of the SAA stations. While awaiting a DORIS data corrective model for the others satellites Jason-3 and Sentinel-3A, we propose here different strategies to minimize the SAA effect on the orbit and also and in particular on the station position estimation. We will compare the DORIS positions of the SAA stations with the GNSS positions collocated.

  16. The Galileo PPS expert monitoring and diagnostic prototype (United States)

    Bahrami, Khosrow


    The Galileo PPS Expert Monitoring Module (EMM) is a prototype system implemented on the SUN workstation that will demonstrate a knowledge-based approach to monitoring and diagnosis for the Galileo spacecraft Power/Pyro subsystems. The prototype will simulate an analysis module functioning within the SFOC Engineering Analysis Subsystem Environment (EASE). This document describes the implementation of a prototype EMM for the Galileo spacecraft Power Pyro Subsystem. Section 2 of this document provides an overview of the issues in monitoring and diagnosis and comparison between traditional and knowledge-based solutions to this problem. Section 3 describes various tradeoffs which must be considered when designing a knowledge-based approach to monitoring and diagnosis, and section 4 discusses how these issues were resolved in constructing the prototype. Section 5 presents conclusions and recommendations for constructing a full-scale demonstration of the EMM. A Glossary provides definitions of terms used in this text.

  17. Causes of informal settlements in Ekurhuleni Metropolitan Municipality: An exploration

    Directory of Open Access Journals (Sweden)

    Noah K. Marutlulle


    Full Text Available This article aims to explore the causes of informal settlements in Ekurhuleni Metropolitan Municipality (EMM. The article strongly challenges the view that the cause of informal settlements in EMM and other parts of South Africa is predominantly the apartheid government and agrees with literature which provides evidence that to a larger extent, the present government, not the apartheid government, is one of the dominant causes of informal settlements. The article further establishes a common and fertile ground for the convergence of the different views and perspectives into variables which, in addition to the present government, include population growth, government economic policies, economic variables, housing shortage, unavailability of land and unaffordability as the real causes of informal settlements in EMM.

  18. Full-genome dissection of an epidemic of severe invasive disease caused by a hypervirulent, recently emerged clone of group A Streptococcus. (United States)

    Fittipaldi, Nahuel; Beres, Stephen B; Olsen, Randall J; Kapur, Vivek; Shea, Patrick R; Watkins, M Ebru; Cantu, Concepcion C; Laucirica, Daniel R; Jenkins, Leslie; Flores, Anthony R; Lovgren, Marguerite; Ardanuy, Carmen; Liñares, Josefina; Low, Donald E; Tyrrell, Gregory J; Musser, James M


    Group A Streptococcus (GAS) causes an exceptionally broad range of infections in humans, from relatively mild pharyngitis and skin infections to life-threatening necrotizing fasciitis and toxic shock syndrome. An epidemic of severe invasive human infections caused by type emm59 GAS, heretofore an exceedingly rare cause of disease, spread west to east across Canada over a 3-year period (2006 to 2008). By sequencing the genomes of 601 epidemic, historic, and other emm59 organisms, we discovered that a recently emerged, genetically distinct emm59 clone is responsible for the Canadian epidemic. Using near-real-time genome sequencing, we were able to show spread of the Canadian epidemic clone into the United States. The extensive genome data permitted us to identify patterns of geographic dissemination as well as links between emm59 subclonal lineages that cause infections. Mouse and nonhuman primate models of infection demonstrated that the emerged clone is unusually virulent. Transmission of epidemic emm59 strains may have occurred primarily by skin contact, as suggested by an experimental model of skin transmission. In addition, the emm59 strains had a significantly impaired ability to persist in human saliva and to colonize the oropharynx of mice, and seldom caused human pharyngitis. Our study contributes new information to the rapidly emerging field of molecular pathogenomics of bacterial epidemics and illustrates how full-genome data can be used to precisely illuminate the landscape of strain dissemination during a bacterial epidemic. Copyright © 2012 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

  19. High Prevalence of Macrolide-resistance and Molecular Characterization of Streptococcus pyogenes Isolates Circulating in China from 2009 to 2016 (United States)

    Lu, Binghuai; Fang, Yujie; Fan, Yanyan; Chen, Xingchun; Wang, Junrui; Zeng, Ji; Li, Yi; Zhang, Zhijun; Huang, Lei; Li, Hongxia; Li, Dong; Zhu, Fengxia; Cui, Yanchao; Wang, Duochun


    Streptococcus pyogenes, or group A Streptococcus, is a pathogen responsible for a wide range of clinical manifestations, from mild skin and soft tissue infections and pharyngitis to severe diseases. Its epidemiological characteristics should be comprehensively under surveillance for regulating the national prevention and treatment practice. Herein, a total of 140 S. pyogenes, including 38 invasive and 102 noninvasive isolates, were collected from infected patients in 10 tertiary general hospitals from 7 cities/provinces in China during the years 2009–2016. All strains were characterized by classical and molecular techniques for its emm types/subtypes, virulent factors and antibiotic resistance profiling. Of 140 isolates, 15 distinct emm types and 31 subtypes were detected, dominated by emm12 (60 isolates, 42.9%), emm1(43, 30.7%), and emm89 (10, 7.1%), and 8 new emm variant subtypes were identified. All strains, invasive or not, harbored the superantigenic genes, speB and slo. The other virulence genes, smeZ, speF, and speC accounted for 96.4, 91.4, and 87.1% of collected isolates, respectively. Further multilocus sequence typing (MLST) placed all strains into 22 individual sequence types (STs), including 4 newly-identified STs (11, 7.9%). All isolates were phenotypically susceptible to penicillin, ampicillin, cefotaxime, and vancomycin, whereas 131(93.5%), 132(94.2%), and 121(86.4%) were resistant to erythromycin, clindamycin, and tetracycline, respectively. Our study highlights high genotypic diversity and high prevalence of macrolide resistance of S. pyogenes among clinical isolates circulating in China. PMID:28642756

  20. DNA-based culture-independent analysis detects the presence of group a streptococcus in throat samples from healthy adults in Japan. (United States)

    Kulkarni, Tejaswini; Aikawa, Chihiro; Nozawa, Takashi; Murase, Kazunori; Maruyama, Fumito; Nakagawa, Ichiro


    Group A Streptococcus (GAS; Streptococcus pyogenes) causes a range of mild to severe infections in humans. It can also colonize healthy persons asymptomatically. Therefore, it is important to study GAS carriage in healthy populations, as carriage of it might lead to subsequent disease manifestation, clonal spread in the community, and/or diversification of the organism. Throat swab culture is the gold standard method for GAS detection. Advanced culture-independent methods provide rapid and efficient detection of microorganisms directly from clinical samples. We investigated the presence of GAS in throat swab samples from healthy adults in Japan using culture-dependent and culture-independent methods. Two throat swab samples were collected from 148 healthy volunteers. One was cultured on selective medium, while total DNA extracted from the other was polymerase chain reaction (PCR) amplified with two GAS-specific primer pairs: one was a newly designed 16S rRNA-specific primer pair, the other a previously described V-Na + -ATPase primer pair. Although only 5 (3.4 %) of the 148 samples were GAS-positive by the culture-dependent method, 146 (98.6 %) were positive for the presence of GAS DNA by the culture-independent method. To obtain serotype information by emm typing, we performed nested PCR using newly designed emm primers. We detected the four different emm types in 25 (16.9 %) samples, and these differed from the common emm types associated with GAS associated diseases in Japan. The different emm types detected in the healthy volunteers indicate that the presence of unique emm types might be associated with GAS carriage. Our results suggest that culture-independent methods should be considered for profiling GAS in the healthy hosts, with a view to obtaining better understanding of these organisms. The GAS-specific primers (16S rRNA and V-Na + -ATPase) used in this study can be used to estimate the maximum potential GAS carriage in people.

  1. Necrotizing soft tissue infections caused by Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis of groups C and G in western Norway. (United States)

    Bruun, T; Kittang, B R; de Hoog, B J; Aardal, S; Flaatten, H K; Langeland, N; Mylvaganam, H; Vindenes, H A; Skrede, S


    Streptococcus pyogenes (group A streptococcus, GAS) is a major cause of necrotizing soft tissue infection (NSTI). On rare occasions, other β-haemolytic streptococci may also cause NSTI, but the significance and nature of these infections has not been thoroughly investigated. In this study, clinical and molecular characteristics of NSTI caused by GAS and β-haemolytic Streptococcus dysgalactiae subsp. equisimilis of groups C and G (GCS/GGS) in western Norway during 2000-09 are presented. Clinical data were included retrospectively. The bacterial isolates were subsequently emm typed and screened for the presence of genes encoding streptococcal superantigens. Seventy cases were identified, corresponding to a mean annual incidence rate of 1.4 per 100 000. Sixty-one of the cases were associated with GAS, whereas GCS/GGS accounted for the remaining nine cases. The in-hospital case fatality rates of GAS and GCS/GGS disease were 11% and 33%, respectively. The GCS/GGS patients were older, had comorbidities more often and had anatomically more superficial disease than the GAS patients. High age and toxic shock syndrome were associated with mortality. The Laboratory Risk Indicator for Necrotizing Fasciitis laboratory score showed high values (≥6) in only 31 of 67 cases. Among the available 42 GAS isolates, the most predominant emm types were emm1, emm3 and emm4. The virulence gene profiles were strongly correlated to emm type. The number of superantigen genes was low in the four available GCS/GGS isolates. Our findings indicate a high frequency of streptococcal necrotizing fasciitis in our community. GCS/GGS infections contribute to the disease burden, but differ from GAS cases in frequency and predisposing factors. © 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.

  2. Erythema multiforme in a patient with recurrent non-hodgkins lymphoma/chronic lymphocytic leukemia

    Directory of Open Access Journals (Sweden)

    Siva Kumara Shankari


    Full Text Available Erythema multiforme major (EMM is a hypersensitivity reaction usually secondary to medications, viruses or other infections. Its presentation is fairly typical with a symmetrical distribution of vesicles, bullae or targeted lesions on the upper body, arms, legs, palms, feet and oral mucosa. The authors present a delineated case of EMM in association with chronic lymphocytic leukemia (CLL and non-Hodgkin′s lymphoma (NHL with a very unusual clinical presentation evolving overtime into a unique, almost dermatomal distribution. Typical therapies were not initially helpful and intravenous immunoglobulin antibody had to be administered.

  3. Energy Efficiency in Ethernet Passive Optical Networks (EPONs): Protocol Design and Performance Evaluation

    DEFF Research Database (Denmark)

    Yan, Ying; Dittmann, Lars


    a suitable wakeup time scheduler at the Optical Line Terminal (OLT). A generic EPON system is considered, which is composed of an OLT and several ONUs that are EMM enabled. An energy consumption optimization problem aimed at saving energy is proposed and two heuristic sleep mode scheduling policies...... Mechanism (EMM) for downlink EPON systems. The proposed mechanism is designed to enhance the standardized control scheme in EPON with the objective to increase energy efficiency while satisfying diverse QoS requirements. The main idea is to put an Optical Network Unit (ONU) into the sleep mode and determine...

  4. 78 FR 77782 - Qualification of Drivers; Exemption Applications; Vision (United States)


    .... Greene (NY) Vincent E. Hardin (AL) Bradley O. Hart (UT) Robert W. Healey, Jr. (NJ) Daniel F. Albers (CA.... Ramirez (TX) Jason W. Rupp (PA) Eric W. Schmidt (MO) Jerry W. Stanfill (AR) Wilfred E. Sweatt (NH) Roger L...

  5. Final Environmental Impact Statement for Proposed Barry M. Goldwater Range East Range Enhancements (Including First and Second Record of Decision) (United States)


    quality and environmental management. Mary Harclerode Production A.A. Business Administration with 2 years experience. Rachel Healey ...Manned Range 3, Barry M Goldwater Range East, Arizona. EcoPlan Associates Mesa, Arizona. Neuzil, Anna, Jill Hjeilman, Jason Sperinck, Daniel

  6. PODAAC-J1IGD-NETGO (United States)

    National Aeronautics and Space Administration — The Jason-1 Interim Geophysical Data Record (IGDR) from the Geodetic mission contain full accuracy altimeter data, with the exception of an interim orbit (accuracy...

  7. Ultrasound (United States)

    ... chap 66. Cosgrove DO, Eckersley RJ, Harvey CJ, Lim A. Ultrasound. In: Adam A, Dixon AK, Gillard JH, Schaefer-Prokop CM, eds. ... by: Jason Levy, MD, Northside Radiology Associates, Atlanta, GA. Also ...

  8. 77 FR 32115 - Ocean Transportation Intermediary License Applicants (United States)


    .... Joseph) S. Lee, President/Treasurer/Secretary (Qualifying Individual), Eun J. Lim, Vice President.... (NVO), 10622 Tammy Street, Cypress, CA 90630, Officers: Jason Hsu, Director/Secretary/Treasurer/CFO...

  9. PODAAC-J2ODR-GPS00 (United States)

    National Aeronautics and Space Administration — Similar to the OSTM/Jason-2 OGDR, but also includes a GPS based orbit and SSHA calculated from that orbit, as supposed to the DORIS based orbit that is already...

  10. OSTM_L2_OST_OGDR_GPS:1 (United States)

    National Aeronautics and Space Administration — Similar to the OSTM/Jason-2 OGDR, but also includes a GPS based orbit and SSHA calculated from that orbit, as supposed to the DORIS based orbit that is already...

  11. PODAAC-J1NRT-GSHA0 (United States)

    National Aeronautics and Space Administration — Near real time Sea surface height anomaly calculated with a GPS based orbit derived from cross overs with OSTM/Jason-2. This provides a more accurate orbit than the...

  12. PODAAC-J2OGR-GPSHA (United States)

    National Aeronautics and Space Administration — This is a near real time dataset that provides a GPS based orbit and Sea Surface Height Anomalies (SSHA) from that orbit. It is similar to the Jason-3 Operation...

  13. Kanada koolimõrv nõudis ühe ohvri / Rein Kärner

    Index Scriptorium Estoniae

    Kärner, Rein


    Veidi enam kui nädal pärast tapatalguid Colorado osariigi Littletoni koolis laskis Kanadas Taberi väikelinnas W. R. Myersi keskkoolis sama kooli endine õpilane Jason Lang maha oma endise koolikaaslase

  14. Pop / Lauri Tikerpe

    Index Scriptorium Estoniae

    Tikerpe, Lauri


    Heliplaatidest: Stereotyp "Keepin' Me", Bent "Intercept!", The Mars Volta "Amputechture", X-press 2 "Makeshift Feelgood", Kosmikud "Pulmad ja matused", Beck "The Information", Ursula "Armastan end aeglaselt", Envy "Insomniac Doze", Joe Colley & Jason Lescalleet "Annihilate This Week"

  15. The inadequate treatment of pain: collateral damage from the war on drugs. (United States)

    Nickerson, Jason W; Attaran, Amir


    Jason Nickerson and Amir Attaran examine the vast inequities in medical pain relief around the world and argue that the global control of licit narcotics be shifted from the International Narcotic Control Board to WHO.

  16. The inadequate treatment of pain: collateral damage from the war on drugs.

    Directory of Open Access Journals (Sweden)

    Jason W Nickerson


    Full Text Available Jason Nickerson and Amir Attaran examine the vast inequities in medical pain relief around the world and argue that the global control of licit narcotics be shifted from the International Narcotic Control Board to WHO.

  17. The Impact of Temporal Geopotential Variations on GPS (United States)

    Melachroinos, Stavros; Lemoine, Frank G.; Zelensky, Nikita P.; Beckley, Brian D.; Chinn, Douglas S.; Nicholas, Joseph B.; McCarthy, John J.; Pennington, Teresa; Luthcke, Scott B.


    Lemoine et al. (2006) and Lemoine et al. (2010) showed that applying more detailed models of time-variable gravity (TVG) improved the quality of the altimeter satellite orbits (e.g. TOPEX/Poseidon, Jason-1, Jason-2). This modeling include application of atmospheric gravity derived from 6-hrly pressure fields obtained from the ECMWF and annual gravity variations to degree & order 20x20 in spherical harmonics derived from GRACE data. This approach allowed the development of a consistent geophysical model for application to altimeter satellite orbit determination from 1993 to 2011. In addition, we have also evaluated the impact of TVG modeling on the POD of Jason-1 and Jason-2 by application of a weekly degree & order four gravity coefficient time series developed using data from ten SLR & DORIS-tracked satellites from 1993 to 2011 (Lemoine et al., 2011).

  18. PODAAC-J1GDR-BINGC (United States)

    National Aeronautics and Space Administration — The Jason-1 Geophysical Data Records (GDR) from the Geodetic mission contain full accuracy altimeter data, with a high precision orbit, provided approximately 35...

  19. PODAAC-J2SDR-IAMR0 (United States)

    National Aeronautics and Space Administration — A correction product to be applied to the OSTM/Jason-2 AMR parameters in the IGDR. This correction product provides better rain and ice flagging and wet tropo...

  20. PODAAC-J2SDR-GAMR0 (United States)

    National Aeronautics and Space Administration — A correction product to be applied to the OSTM/Jason-2 AMR parameters in the GDR. This correction product provides better rain and ice flagging and wet tropo...

  1. PODAAC-J1SDR-BIG0C (United States)

    National Aeronautics and Space Administration — The Jason-1 binary Sensory Geophysical Data Record (SGDR) from the Geodetic mission contains all the same parameters as the binary GDR but also contains the...

  2. AT26-10 Chemosynthetic Microbial Communities at Deep-Sea Vents (EM122) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The cruise will include 16 dives with DSV Alvin or ROV Jason, to allow time for deployment and collection of experiments and for extensive sampling of discrete vents...

  3. Lophelia II 2009: Deepwater Program: Exploration and Research of Northern Gulf of Mexico Deepwater Natural and Artificial Hard Bottom Habitats with Emphasis on Coral Communities: Reefs, Rigs and Wrecks on NOAA Ship Ronald H. Brown between 20090819 and 20090912 (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This cruise used the remotely operated vehicle (ROV) Jason II to: explore 4-6 new sites for the occurrence of deep water coral reefs; made collections of Lophelia...

  4. Oceanographic Data collected during the Lophelia II 2009: Deepwater Program: Exploration and Research of Northern Gulf of Mexico Deepwater Natural and Artificial Hard Bottom Habitats with Emphasis on Coral Communities: Reefs, Rigs and Wrecks on NOAA Ship Ronald H. Brown between 2009-08-19 to 2009-09-12 (NODC Accession 0081782) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This cruise used the remotely operated vehicle (ROV) Jason II to: explore 4-6 new sites for the occurrence of deep water coral reefs; made collections of Lophelia...

  5. Automated Analysis of Zooplankton Size and Taxonomic Composition

    National Research Council Canada - National Science Library

    Davis, C. N


    .... The VPR has also been deployed on the ROV JASON for individual particle tracking, and a moored profiling system is under development, which will include on-board image processing and satellite telemetry of processed data.

  6. PODAAC-J1OSD-BINGO (United States)

    National Aeronautics and Space Administration — The Jason-1 Operational Sensor Data Record (OSDR) Geodetic Mission is a Near Real Time (NRT) wind/wave oriented dataset, dedicated to meteorological users. Its...

  7. Stormwater Calculator (SWC) webinar (United States)

    Jason Berner presents EPA’s National Stormwater Calculator developed to help support local, state and national stormwater management objectives and regulatory efforts to reduce runoff using green infrastructure practices as low impact development controls.

  8. Submersible Data (Dive Trackpoints) for Expedition to the Deep Slope 2007 - Office of Ocean Exploration (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data and information collected by the ROV Jason along its track during sixteen dives of the 2007 "Expedition to the Deep Slope" expedition sponsored by the National...

  9. Moving Beyond "Food Deserts": Reorienting United States Policies to Reduce Disparities in Diet Quality.

    Directory of Open Access Journals (Sweden)

    Jason P Block


    Full Text Available Jason Block and S. V. Subramanian explore avenues for improving the health of Americans through reducing dietary inequalities and look at whether concern over "food deserts" has been taken too far.

  10. 78 FR 78475 - Qualification of Drivers; Exemption Applications; Vision (United States)


    .... Kimmet, Jr. (WA) Robert C. Leathers (MO) Jason L. Light (ID) Kenneth R. Murphy (WA) Michael J. Richard (LA) Robert E. Sanders (PA) Robert A Sherry (PA) Stephen G. Sniffin (CT) John R. Snyder (WA) The...

  11. 75 FR 1451 - Qualification of Drivers; Exemption Applications; Vision (United States)


    ...., Ronald D. Boeve, Arthur L. Bousema, Matthew W. Daggs, Donald R. Date, Jr., John E. Kimmet, Jr., Robert C. Leathers, Jason L. Light, Robert Mollicone, Kenneth R. Murphy, Robert A. Sherry, Stephen G. Sniffin, John R...

  12. Integrating Non-Tidal Sea Level data from altimetry and tide gauges for coastal sea level prediction

    DEFF Research Database (Denmark)

    Cheng, Yongcun; Andersen, Ole Baltazar; Knudsen, Per


    The main objective of this paper is to integrate Non-Tidal Sea Level (NSL) from the joint TOPEX, Jason-1 and Jason-2 satellite altimetry with tide gauge data at the west and north coast of the United Kingdom for coastal sea level prediction. The temporal correlation coefficient between altimetric...... NSLs and tide gauge data reaches a maximum higher than 90% for each gauge. The results show that the multivariate regression approach can efficiently integrate the two types of data in the coastal waters of the area. The Multivariate Regression Model is established by integrating the along-track NSL...... from the joint TOPEX/Jason-1/Jason-2 altimeters with that from eleven tide gauges. The model results give a maximum hindcast skill of 0.95, which means maximum 95% of NSL variance can be explained by the model. The minimum Root Mean Square Error (RMSe) between altimetric observations and model...

  13. 77 FR 65536 - Notice To Solicit Applications for the Ocean Exploration Advisory Board (United States)


    ... required. Dated: October 23, 2012. Jason Donaldson, Chief Financial Officer/Chief Administrative Officer... enable them to provide expert advice concerning the Ocean Exploration Program's roles within the context...

  14. Uusi heliplaate / Tõnu Pedaru

    Index Scriptorium Estoniae

    Pedaru, Tõnu


    Heliplaatidest " Jordan Knight "S/T", "Full Of House", Clinton "Disco & The Halfway To Discontent", Apollo 440 "Gettin" High On Your Own Supply", Ben & Jason "Emoticons", Murry The hump "Thrown Like A Stone"

  15. Submarine Ring of Fire 2014 - Ironman (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — There will be 4 primary data types collected, multibeam sonar data, CTD water column data, hydrophone records, and Jason ROV dive data.

  16. PODAAC-J1GDR-BIN0C (United States)

    National Aeronautics and Space Administration — The Jason-1 Geophysical Data Records (GDR) contain full accuracy altimeter data, with a high precision orbit (accuracy ~2.5 cm), provided approximately 35 days after...

  17. An Integrated Research Program for the Modeling, Analysis and Control of Aerospace Systems (United States)


    Fabiano, Jr. - Brown University Mitchell Feigenbaum - Rockefeller University Elena Fernandez - Institudo de Desarrollo Techologico, para la Industria ...Minnesota James Sochacki - ISC, LaRamie, Wyoming Felippe de Souza - Instituto Tecnologico de Aeronautica Jason L. Speyer - University of Texas Eitan Tadmor



    europe/6665195.stm. 20 Andreas Schmidt, “The Estonian Cyberattacks,” in A Fierce Domain : Conflict in Cyberspace, 1986 to 2012, ed. Jason Healey. Cyber...against-cyberwarfare Schmidt, Andreas. “The Estonian Cyberattacks.” In A Fierce Domain : Conflict in Cyberspace, 1986 to 2012. Edited by Jason...the first known use of cyber in tandem with a conflict in the physical domain .33 Interestingly enough, one could argue that the war had started prior

  19. Looking Back To The Future Of Cyberspace Warfare (United States)

    2016-05-26 13 Jason Healey and Karl Grindal, eds. A Fierce Domain : Conflict in Cyberspace, 1986 to 2012 (Arlington, VA: Cyber Conflict...Healey, Jason and Karl Grindal, eds. A Fierce Domain : Conflict in Cyberspace, 1986 to 2012. Arlington, VA: Cyber Conflict Studies Association, 2013...should be viewed as another domain in which to operate, in other words a different or additional battles pace. Cyberspace should also be viewed as



    attack-on-syrias-al-kibar-nuclear-facility/. 45 Jason Healey, ed., A Fierce Domain : Conflict in Cyberspace, 1986 to 2012 (Vienna, VA: Cyber Conflict...targeted-private-german- companies- a -961444.html. Healey, Jason, ed. A Fierce Domain : Conflict in Cyberspace, 1986 to 2012. Vienna, VA: Cyber Conflict...capabilities in a way that U.S. involvement can be denied.3 Thomas Rid basically asserts the same for the cyber domain and defines this type of covert

  1. Hollow Threats: Why Coercive Diplomacy Fails (United States)


    130 Healey , Jason. A Fierce Domain : Conflict in Cyberspace, 1986 to 2012. Washington, DC: Atlantic Council, 2013. Henriksen, Dag. NATO’s, including P-1 centrifuges, to the US. Those centrifuges ended up in the Oak Ridge National Labaratory in Tennessee. Jason Healey , A ... Fierce Domain : Conflict in Cyberspace, 1986 to 2012 (Washington, DC: Atlantic Council, 2013), 226. 12. Quoted in Andrew, “British Perceptions of

  2. Regionally Aligned Forces: Concept Viability and Implementation (United States)


    Healey and John A. Bonin, Ph.D. RAF and SOF Integration 97 Colonel Scott W. Kelly and Colonel Chad A. Mcgougan RAF and ARFORGEN 110 Colonel Robert...Washington, DC: U.S. Department of the Army, September 04, 2012, p. 2. 4 Kimberly Field, James Learmont and Jason Charland, “Regionally Aligned Forces...October 25, 2013. Field, Kimberly, Learmont, James and Charland, Jason , “Regionally Aligned Forces; Business Not as Usual,” Parameters Vol. 43, No

  3. Adoptable Afghan Customs or Practices in a Military Operations Environment (United States)


    its culture, shows little of the interactions with western cultures. Novels by Said Hyder Akbar, Jason Elliot, Anne Seierstad, and Khaled Hosseini...Press, Princeton, NJ, 1973. Elliot, Jason , An Unexpected Light. New York, NY: Picador, 2001. ________, FM 3-24: Counterinsurgency. Washington DC...Afghanistan,‖ Third World Quarterly 23, no 5, (2002): 977-989. Healey , Edward J. Jr., (MAJ, USMC), ―Cultural Competency Training in the United States

  4. Attribution, Delayed Attribution and Covert Cyber-Attack: Under what Conditions should the United States Publicly Acknowledge Responsibility for Cyber Operations? (United States)


    Gregory Rattray and Jason Healey , in their article “Categorizing and Understanding Offensive Cyber Capabilities and Their Use,” examine what types...www.rfc- Rattray, Gregory, and Jason Healey . “Categorizing and Understanding Offensive Cyber...which is built upon later. 19 Rattray and Healey examine the different types of cyber-attacks that may be employed among states in “Categorizing and

  5. Galileo: Power, Pride, and Profit. The Relative Influence of Realist, Ideational, and Liberal Factors on the Galileo Satellite Program (United States)


    pointed out that NATO 70 Ralph Braibanti, Jason Y. Kim and Damon Wells, “GPS-Galileo Negotiations...scale.7 The Director of Galileo Industries at the time, Mike Healey (reaffirming a view also reported in November 2001)8 said, “The cost and financing...Vision.” Space Policy 22 (2006): 92-99. Braibanti, Ralph, Jason Y. Kim and Damon Wells. “GPS-Galileo Negotiations: Commercial Issues at Stake

  6. Hydrogen bonding in thiobenzamide synthon and its Cadmium ...

    Indian Academy of Sciences (India)

    Seena E B, Kurup M R P and Suresh E 2008 J. Chem. Crystallogr. 38 93. 25. Mahmood-ul-Hassan K, Shahid H, Tashfeen A and. Jason D M 2009 Acta Cryst. E65 1128. 26. Mahmood-ul-Hassan K, Shahid H, Tashfeen A and. Jason D M 2009 Acta Cryst. E65 1333. 27. Mahmood-ul-Hassan K, Shahid H, Tashfeen A and.

  7. Aircraft Evaluation Using Stochastic Duels (United States)


    LEFT BLANK xix EXECUTIVE SUMMARY In this thesis, we present a modeling paradigm for evaluating fighter aircraft using stochastic duels... EVALUATION USING STOCHASTIC DUELS by Jason W.C. Gay September 2017 Thesis Advisor: Moshe Kress Co-Advisor: Michael Atkinson Second Reader...DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE AIRCRAFT EVALUATION USING STOCHASTIC DUELS 6. AUTHOR(S) Jason W.C. Gay 7. PERFORMING

  8. The Great War and German Memory

    DEFF Research Database (Denmark)

    Leese, Peter


    Review essay on Jason Crouthamel, The Great War and German Memory. Society, Politics and Psychological Trauma, 1914-18 (2009) and Anton Kaes, Shell Shock Cinema: Weimar Culture and the Wounds of War (2009)......Review essay on Jason Crouthamel, The Great War and German Memory. Society, Politics and Psychological Trauma, 1914-18 (2009) and Anton Kaes, Shell Shock Cinema: Weimar Culture and the Wounds of War (2009)...

  9. U.S. Navy Employment Options for Unmanned Surface Vehicles (USVs) (United States)


    Savitz, Irv Blickstein, Peter Buryk, Robert W. Button, Paul DeLuca, James Dryden, Jason Mastbaum, Jan Osburg, Philip Padilla, Amy Potter, Carter C...VEHICLES (USVs) Scott Savitz, Irv Blickstein, Peter Buryk, Robert W. Button, Paul DeLuca, James Dryden, Jason Mastbaum, Jan Osburg, Philip Padilla, Bertram, Volker, “Unmanned Surface Vehicles: A Survey,” Brest , France: ENSIETA, 2008. As of

  10. Learning for Semantic Parsing Using Statistical Syntactic Parsing Techniques (United States)


    Committee: Raymond J. Mooney, Supervisor Jason M. Baldridge Risto Miikkulainen Martha Palmer Bruce W. Porter Learning for Semantic Parsing Using... Baldridge , Risto Miikku- lainen, Martha Palmer, Bruce Porter, and the former member, Ben Kuipers. I have a deeper understanding of the research thanks to...their insight and suggestions. I am especially grateful to Jason Baldridge for his valuable advice and help on my job hunting besides research. I would

  11. The Effect of Prosthetic Socket Interface Design on Socket Comfort, Residual Limb Health, and Function for the Transfemoral Amputee (United States)


    for the Transfemoral Amputee PRINCIPAL INVESTIGATOR: M. Jason Highsmith CONTRACTING ORGANIZATION: University of South Florida Tampa, FL 33620 REPORT...and Function for the Transfemoral Amputee 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Highsmith, M. Jason 5d...There are two alternative interface designs for the military and veteran above knee amputee that could provide answers to issues germane to above

  12. Best Practices in the Design of Aerobic Training Programs (United States)


    A., & Nadel, E. R. (1993). Effect of exercise training on cardiopulmonary baroreflex control of forearm vascular resistance in humans. Med Sci...Naval Health Research Center Best Practices in the Design of Aerobic Training Programs Jason Jameson, Ph.D. Ross R. Vickers Jr., Ph.D...Aerobic Training Programs Jason Jameson Ross R. Vickers, Jr. Warfighter Performance Department Naval Health Research Center 140 Sylvester Road

  13. Etude physicochimique de l'huile essentielle de Ruta Chalepensis L ...

    African Journals Online (AJOL)

    Ruta chalepensis L. (Rutacée), est une plante aromatique médicinale encore utilisée dans la médecine traditionnelle de nombreux pays comme laxatif, antiinflammatoire, analgésique, antipasmodique, abortif, antiépileptique, emménagogue et pour le traitement de pathologies cutanées. Des screening phytochimiques ont ...

  14. Does Barbie Make Girls Want to be Thin? The Effect of Experimental Exposure to Images of Dolls on the Body Image of 5- to 8-Year-Old Girls (United States)

    Dittmar, Helga; Halliwell, Emma; Ive, Suzanne


    The ubiquitous Barbie doll was examined in the present study as a possible cause for young girls' body dissatisfaction. A total of 162 girls, from age 5 to age 8, were exposed to images of either Barbie dolls, Emme dolls (U.S. size 16), or no dolls (baseline control) and then completed assessments of body image. Girls exposed to Barbie reported…

  15. Systems analysis of Mycoplasma hyopneumoniae to improve vaccine production

    NARCIS (Netherlands)

    Kamminga, Tjerko


    Mycoplasma hyopneumoniae (<em>M. hyopneumoniae) is a bacterial pathogen that has evolved from a gram-positive ancestor and specifically colonizes the lower respiratory tract of pigs where it causes enzootic pneumonia and plays a major role in the development of respiratory disease

  16. Differential search algorithm-based parametric optimization of electrochemical micromachining processes

    Directory of Open Access Journals (Sweden)

    Debkalpa Goswami


    Full Text Available Electrochemical micromachining (EMM appears to be a very promising micromachining process for having higher machining rate, better precision and control, reliability, flexibility, environmental acceptability, and capability of machining a wide range of materials. It permits machining of chemically resistant materials, like titanium, copper alloys, super alloys and stainless steel to be used in biomedical, electronic, micro-electromechanical system and nano-electromechanical system applications. Therefore, the optimal use of an EMM process for achieving enhanced machining rate and improved profile accuracy demands selection of its various machining parameters. Various optimization tools, primarily Derringer’s desirability function approach have been employed by the past researchers for deriving the best parametric settings of EMM processes, which inherently lead to sub-optimal or near optimal solutions. In this paper, an attempt is made to apply an almost new optimization tool, i.e. differential search algorithm (DSA for parametric optimization of three EMM processes. A comparative study of optimization performance between DSA, genetic algorithm and desirability function approach proves the wide acceptability of DSA as a global optimization tool.

  17. An effective medium model versus a network model for nano-structured solar cells

    International Nuclear Information System (INIS)

    Minnaert, B.; Grasso, C.; Burgelman, M.


    In this paper, two methods are compared to model the I-V curves of nano-structured solar cells. These cells consist of an interpenetrating network of an n-type transparent semiconductor oxide (e.g. TiO 2 ) and a p-type semiconductor absorber (e.g. CdTe, CuInS 2 ), deposited on TCO covered glass. The methods are also applicable when a dye and an electrolyte replace the p-semiconductor, and even to organic bulk heterojunction cells. A network model (NM) with resistors and diodes has been published by us before. Another method which has been proposed in the literature is an effective medium model (EMM). In this model, the whole p-n nano-structure is represented by one single effective semiconductor layer, which then is fed into a standard solar cell device simulator, e.g. SCAPS. In this work, it is shown that the NM and the EMM can describe the same physical structure, when they are set up properly. As an illustration, some problems are described both by EMM and NM, and the results are compared. The EMM in this work confirms the results obtained earlier with a simplified NM (constant R n , R p ): when illuminating the n-side, the structure is tolerant to R n but not to R p ; the interpenetrating geometry is disadvantageous for V oc . (authors)

  18. Climate change and urban development in southern Africa: The ...

    African Journals Online (AJOL)


    Jul 24, 2013 ... on water services including water resource management and disaster risk reduction, such as flash flooding in Ekurhuleni. (EMM), are presented. .... of implementation may seriously hamper the cost-efficiency of water delivery into .... affected by pollution from sewage works, human settlements, mining and ...

  19. Model documentation: Electricity Market Module, Electricity Fuel Dispatch Submodule

    Energy Technology Data Exchange (ETDEWEB)


    This report documents the objectives, analytical approach and development of the National Energy Modeling System Electricity Fuel Dispatch Submodule (EFD), a submodule of the Electricity Market Module (EMM). The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, model source code, and forecast results generated through the synthesis and scenario development based on these components.

  20. Interaction between root-knot nematodes and Solanum spp. : variation in pathogenicity, cytology, proteins and DNA = [De interactie tussen wortelknobbelnematoden en Solanum spp. : variatie in ziekteverwekkend vermogen, cytologie, eiwitten en DNA

    NARCIS (Netherlands)

    Beek, van der J.G.


    This thesis describes genetic variation in the root-knot nematodes Meloidogyne hapla, M. chitwoodi and <em>M. fallax, particularly with respect to their pathogenicity on Solanum spp. Significant differences in virulence and

  1. Education for Survival. A Project Under Title II Elementary and Secondary Education Act of 1965 for Fiscal Year 1973, School Year 1973-1974. (United States)

    Westminister School District 50, CO.

    Education for Survival (EFS) was a project, funded under ESEA Title II, to provide elementary and secondary school teachers in District 50 of Colorado with multimedia materials on environmental education. Materials were stored and delivered to the schools in a mobile educational resources center/classroom (ECO-EMM). The bulk of this document…

  2. Climate change and urban development in southern Africa: The ...

    African Journals Online (AJOL)

    In this paper, outcomes from an investigation of plausible climate futures over the next century, and the potential impacts on water services including water resource management and disaster risk reduction, such as flash flooding in Ekurhuleni (EMM), are presented. Four key aspects are examined: (i) the extent to which the ...

  3. Self-Regulated Learning from Illustrated Text: Eye Movement Modelling to Support Use and Regulation of Cognitive Processes during Learning from Multimedia (United States)

    Scheiter, Katharina; Schubert, Carina; Schüler, Anne


    Background: When learning with text and pictures, learners often fail to adequately process the materials, which can be explained as a failure to self-regulate one's learning by choosing adequate cognitive learning processes. Eye movement modelling examples (EMME) showing how to process multimedia instruction have improved elementary school…

  4. Fantastilisi hirmuelamusi neljandat aastat / Aare Ermel

    Index Scriptorium Estoniae

    Ermel, Aare, 1957-2013


    17.-19. aprillini Haapsalu Kultuurikeskuses toimuvast 4. Haapsalu Õudus- ja Fantaasiafilmide festivalist. Mõningate filmide tutvustusi: festivali avafilm soomlase AJ Annila "Saun", Patrick Syverseni "Inimjaht" (Norra), Gunnar B. Gudmundssoni "Astropia" (Island), Jose Mojica Marinsi "Kurjuse kehastus", inglase Steven Sheili "Emme&Issi" ning teise inglase Simeon Halligani "Killustunud"

  5. Scarlet fever is caused by a limited number of Streptococcus pyogenes lineages and is associated with the exotoxin genes ssa, speA and speC. (United States)

    Silva-Costa, Catarina; Carriço, Joao A; Ramirez, Mario; Melo-Cristino, Jose


    Several outbreaks of scarlet fever caused by Streptococcus pyogenes were recently reported. Scarlet fever is historically considered a toxin-mediated disease, dependent on the production of the exotoxins SpeA and SpeC, but a strict association between scarlet fever and these exotoxins is not always detected. The aims of this study were to characterize the scarlet fever bacterial isolates recovered from patients in a Lisbon hospital and to identify any distinctive characteristics of such isolates. We characterized a collection of 303 pharyngeal S. pyogenes collected between 2002 and 2008. One-hundred and one were isolated from scarlet fever patients and 202 were associated to a diagnosis of tonsillo-pharyngitis. Isolates were characterized by T and emm typing, pulsed field gel electrophoresis profiling and superantigen gene profiling. The diversity of the scarlet fever isolates was lower than that of the pharyngitis isolates. Specific lineages of emm87, emm4 and emm3 were overrepresented in scarlet fever isolates but only 1 pulsed field gel electrophoresis major lineage was significantly associated with scarlet fever. Multivariate analysis indicated associations of ssa, speA and speC with scarlet fever. In nonoutbreak conditions, scarlet fever is caused by a number of distinct genetic lineages. The lower diversity of these isolates and the association with specific exotoxin genes indicates that some lineages are more prone to cause this presentation than others even in nonoutbreak conditions.

  6. Description of the Pathogenic Features of Streptococcus pyogenes Isolates from Invasive and Non-Invasive Diseases in Aichi, Japan. (United States)

    Matsumoto, Masakado; Yamada, Kazuhiro; Suzuki, Masahiro; Adachi, Hirokazu; Kobayashi, Shinichi; Yamashita, Teruo; Minagawa, Hiroko; Tatsuno, Ichiro; Hasegawa, Tadao


    We identified hypervirulent Streptococcus pyogenes in 27 and 420 isolates from patients with invasive and non-invasive diseases, respectively, in Aichi Prefecture, Japan, between 2003 and 2012, in an attempt to understand why the prevalence of streptococcal toxic shock syndrome (STSS) suddenly increased in this location during 2011. Hypervirulent strains belong to the emm1 genotype, with a mutation in the covR/S genes that regulate many other genes, encoding virulence determinants and resulting in the absence of the proteinase streptococcal exotoxin B and the production of virulence factors such as the superantigen streptococcal exotoxin A, the nuclease streptococcal DNase, the cytotoxin NAD-glycohydrolase, and the hemolysin streptolysin O. We found 1 strain from invasive disease and 1 from non-invasive disease with traits similar to those of hypervirulent strains, except that the sda1 gene was absent. We also found 1 non-emm1 strain with phenotypic and genetic traits identical to those of the emm1 hypervirulent strains except that it did not belong to emm1 genotype, from non-invasive diseases cases in 2011. These findings suggested that hypervirulent and hypervirulent-like strains from invasive and non-invasive disease cases could have at least partially contributed to the sudden increase in the number of patients with STSS in Aichi during 2011.

  7. On ecology and control of Mycocentrospora acerina in caraway (Carum carvi)

    NARCIS (Netherlands)

    Evenhuis, A.


    This thesis describes aspects of the biology of Mycocentrospora acerina (Hart.) Deighton and their implications for caraway ( Carum carvi L.) cultivation. The biology of <em>M. acerina under field conditions was not yet described

  8. Clinical and epidemiological aspects of invasive Streptococcus pyogenes infections in Denmark during 2003 and 2004

    DEFF Research Database (Denmark)

    Luca-Harari, B.; Linden, M. van der; Staum-Kattoft, M.


    being higher in patients more than 70 years of age (36.5%). For streptococcal toxic shock syndrome (STSS) and necrotizing fasciitis the CFRs were 53% and 25%, respectively. Out of 16 T types recorded, three predominated: T28 (23%), T1 (22%), and the cluster T3/13/B3264 (14%). Among 21) different emm...

  9. An Overview of Major Terrestrial, Celestial, and Temporal Coordinate Systems for Target Tracking (United States)


    Radiocommunication Sector ISO International Organization for Standardization ECOSOC UN Economic and Social Council UN United Nations ITU International...atomic scale) ECEF Earth-Centered Earth-Fixed ECI Earth-Centered Inertial ECOSOC UN Economic and Social Council EGM2008 Earth Gravitation Model EMM 2010

  10. Numerical simulation of scale-up effects of methanol-to-olefins fluidized bed reactors

    DEFF Research Database (Denmark)

    Lu, Bona; Zhang, Jingyuan; Luo, Hao


    factors and is expected to speed up the experiment-based scale-up process with lower cost. In this study, we aim to investigate the scale-up effects through simulations of a series of methanol-to-olefins (MTO) reactors of different sizes. The two-fluid model and energy-minimization multi-scale (EMMS...

  11. Learning AirWatch

    CERN Document Server

    Dunkerley, Mark


    If you are a technical professional who wants to dive deeper into the functionality offered by AirWatch or manage the solution, then this book will help you choose the best set of configuration, device management, and monitoring options that you can use to effectively manage your EMM implementation.

  12. Browse Author Index

    African Journals Online (AJOL)

    Habori, M · Al-Hakimi, MS · Al-Raway, AM · Al-Rifai, MF · Al-Saadany, MM · Alaziz Gaber, OA · Alfayomi, Ghada · Alghasham, AA · Alhadad, O · Ali, E · Ali, E M · Ali, Ehab MM · Ali, Ehab MM · Ali, EMM · Ali, Heba Said · Ali, M

  13. Antihyperglycaemic activity of the methanol extract from leaves of Eremophila maculata (Scrophulariaceae) in streptozotocin-induced diabetic rats. (United States)

    Youssef, Fadia S; Ashour, Mohamed L; Ebada, Sherif S; Sobeh, Mansour; El-Beshbishy, Hesham A; Singab, Abdel Nasser; Wink, Michael


    This study was designed to evaluate the antihyperglycaemic activity of the methanol leaf extract of Eremophila maculata (EMM) both in vitro and in vivo. The antihyperglycaemic activity was assessed in vitro using differentiated 3T3-L1 adipocytes, whereas in-vivo effect was evaluated in streptozotocin-induced diabetic rats. Chemical profiling of EMM was done using LC-ESI-MS techniques. Molecular modelling experiments of the identified compounds were performed using C-Docker protocol. Eremophila maculata slightly enhanced cellular glucose uptake and utilization in vitro by 3.92% relative to the untreated control. A stronger in-vivo effect was observed for EMM and its dichloromethane fraction. A pronounced elevation in serum insulin by 88.89 and 66.67%, respectively, accompanied by an apparent decline in fasting blood glucose (FBG) level by 65.60 and 70.37% comparable to streptozotocin-induced diabetic rats was observed. This effect was stronger than that of the reference drug glibenclamide (GLB). Chemical profiling of EMM revealed that leucoseptoside A, verbascoside, syringaresinol-4-O-β-D-glucopyranoside, pinoresinol-4-O-β-D-glucopyranoside and pinoresinol-4-O-[6″-O-(E)-feruloyl]-β-D-glucopyranoside are the major compounds. Molecular modelling showed that martynoside, verbascoside and phillygenin exhibited the highest inhibition to human pancreatic α-amylase (HPA), maltase glucoamylase (MGAM) and aldose reductase (AR), respectively. Eremophila maculata offers an interesting relatively safer antihyperglycaemic candidate comparable to synthetic analogues. © 2017 Royal Pharmaceutical Society.

  14. Streptococcus pyogenes strains in Sao Paulo, Brazil: molecular characterization as a basis for StreptInCor coverage capacity analysis. (United States)

    Freschi de Barros, Samar; De Amicis, Karine Marafigo; Alencar, Raquel; Smeesters, Pierre Robert; Trunkel, Ariel; Postól, Edilberto; Almeida Junior, João Nóbrega; Rossi, Flavia; Pignatari, Antonio Carlos Campos; Kalil, Jorge; Guilherme, Luiza


    Several human diseases are caused by Streptococcus pyogenes, ranging from common infections to autoimmunity. Characterization of the most prevalent strains worldwide is a useful tool for evaluating the coverage capacity of vaccines under development. In this study, a collection of S. pyogenes strains from Sao Paulo, Brazil, was analyzed to describe the diversity of strains and assess the vaccine coverage capacity of StreptInCor. Molecular epidemiology of S. pyogenes strains was performed by emm-genotyping the 229 isolates from different clinical sites, and PCR was used for superantigen profile analysis. The emm-pattern and tissue tropism for these M types were also predicted and compared based on the emm-cluster classification. The strains were fit into 12 different emm-clusters, revealing a diverse phylogenetic origin and, consequently, different mechanisms of infection and escape of the host immune system. Forty-eight emm-types were distinguished in 229 samples, and the 10 most frequently observed types accounted for 69 % of all isolates, indicating a diverse profile of circulating strains comparable to other countries under development. A similar proportion of E and A-C emm-patterns were observed, whereas pattern D was less frequent, indicating that the strains of this collection primarily had a tissue tropism for the throat. In silico analysis of the coverage capacity of StreptInCor, an M protein-conserved regionally based vaccine candidate developed by our group, had a range of 94.5 % to 59.7 %, with a mean of 71.0 % identity between the vaccine antigen and the predicted amino acid sequence of the emm-types included here. This is the first report of S. pyogenes strain characterization in Sao Paulo, one of the largest cities in the world; thus, the strain panel described here is a representative sample for vaccine coverage capacity analysis. Our results enabled evaluation of StreptInCor candidate vaccine coverage capacity against diverse M-types, indicating

  15. Defense Infrastructure: Department of Defense Renewable Energy Initiatives (United States)


    to this report include Harold Reich, Assistant Director; Stacy Bennett; Sharon Reid; Rebecca Rygg; Christopher Turner; and Michael Willems...Photovoltaic Fully Operational 2010 No 2009 1 $37.54 $37.54 Appropriated 183 Dept Navy Naval Base San Diego CA 200 kW PV Carport, McCandless Blvd Sub...Notes from the Department of Defense 183 Dept Navy Naval Base San Diego CA 200 kW PV Carport, McCandless Blvd Sub-Station Parking Lot 0.00 0.00

  16. Outline of a fuel treatment facility in NUCEF

    International Nuclear Information System (INIS)

    Sugikawa, Susumu; Umeda, Miki; Kokusen, Junya


    This report presents outline of the nuclear fuel treatment facility for the purpose of preparing solution fuel used in Static Experiment Critical Facility (STACY) and Transient Experiment Critical Facility (TRACY) in Nuclear Fuel Cycle Safety Engineering Research Facility (NUCEF), including descriptions of process conditions and dimensions of major process equipments on dissolution system of oxide fuel, chemical adjustment system, purification system, acid recovery system, solution fuel storage system, and descriptions of safety design philosophy such as safety considerations of criticality, solvent fire, explosion of hydrogen and red-oil and so on. (author)

  17. AOAC method 966.04: preliminary evaluation of cooked meat medium with manganese sulfate for the cultivation of Clostridium sporogenes: precollaborative study. (United States)

    Tomasino, Stephen F; Samalot-Freire, Luisa C


    AOAC Method 966.04, the Sporicidal Activity of Disinfectants Test, is a carrier-based test that provides a qualitative measure of product efficacy against spores of Bacillus subtilis and Clostridium sporogenes. For regulatory purposes, Method 966.04 is accepted by the U.S. Environmental Protection Agency (EPA) and the U.S. Food and Drug Administration (FDA) for the generation of product performance data for sporicides and sterilants. In this study, we report on findings associated with proposed improvements (modifications) to the Clostridium component of the method. Egg meat medium (EMM), the culture medium for C. sporogenes currently specified in the method, is no longer commercially available and finding a suitable replacement is critical. In addition, the use of a nonstandardized extract of raw soil as an amendment to EMM, as stipulated in the current method, may result in a highly variable spore suspension. The primary focus of this study was to find replacements for EMM and soil extract. A carrier count procedure, the establishment of target carrier counts (spores/carrier), and a neutralization confirmation procedure were also evaluated. The study was limited to liquid products tested against Clostridium on a hard surface carrier (porcelain penicylinder). Spore suspensions of C. sporogenes were generated using: (1) EMM with soil extract (EMM/SE), (2) cooked meat medium with soil extract (CMM/SE), and (3) cooked meat medium with 5 microg/mL manganese sulfate (CMM/MnSO4). The titer of the spore suspension, carrier counts, resistance to hydrochloric acid (HCI), and efficacy against 3 liquid sporicidal agents were used to evaluate the potential of CMM and MnSO4 as replacements. The study was performed by the EPA Office of Pesticide Programs Microbiology Laboratory, Fort Meade, MD. Use of CMM/SE and CMM/MnSO4 resulted in comparable results for titer of spore suspensions (approximately 10(8) spores/mL) and carrier counts (approximately 3 x 10(6) spores/carrier). The

  18. Predominant role of msr(D) over mef(A) in macrolide resistance in Streptococcus pyogenes. (United States)

    Zhang, Yan; Tatsuno, Ichiro; Okada, Ryo; Hata, Nanako; Matsumoto, Masakado; Isaka, Masanori; Isobe, Ken-ichi; Hasegawa, Tadao


    In Japan, the number of patients with streptococcal toxic shock syndrome is reported to be increasing. mef(A) gene-positive macrolide-resistant emm1 strains are thought to possibly contribute to the rise in the frequency of STSS. Although analyses of macrolide-resistant mechanisms, including mef(A) resistance, have been performed mainly in Streptococcus pneumoniae, the role of this gene in Streptococcus pyogenes has not been completely investigated. Therefore, to the best of our knowledge, we established the first mef(A)-knockout strain using an emm1-type S. pyogenes strain, and tested its susceptibility to erythromycin, clarithromycin and azithromycin. We found that the antimicrobial susceptibilities were almost identical to those of the parental strain. Hence, we established a knockout strain for another gene, msr(D), that is located immediately downstream of mef(A). The macrolide resistances of the resulting strain significantly decreased, and were further altered when both mef(A) and msr(D) were knocked out. The introduction of the msr(D) gene into a macrolide-sensitive strain conferred more resistance than the introduction of the mef(A) gene. The erythromycin susceptibilities of knockout strains were further dissected using two additional emm4- and emm75-type S. pyogenes strains. We found almost identical results for both strains except for the mef(A) knockout emm4 type, whose susceptibility was altered, although the change was less than that for the msr(D) knockout. These results suggest that both mef(A) and msr(D) are involved in macrolide resistance in S. pyogenes, and that the msr(D) gene plays a more predominant role in macrolide resistance than mef(A).

  19. Molecular characterization of macrolide resistant Streptococcus pyogenes isolates from pharyngitis patients in Serbia. (United States)

    Opavski, Natasa; Gajic, Ina; Borek, Anna L; Obszańska, Katarzyna; Stanojevic, Maja; Lazarevic, Ivana; Ranin, Lazar; Sitkiewicz, Izabela; Mijac, Vera


    A steady increase in macrolide resistance in Streptococcus pyogenes, group A streptococci (GAS) was reported in Serbia during 2004-2009 (9.9%). However, there are no data on the molecular epidemiology of pharyngeal macrolide resistance GAS (MRGAS) isolates. Therefore, the aims of this first nationwide study were to examine the prevalence of macrolide resistance in Serbian GAS and to determine their resistance phenotypes, genotypes and clonal relationships. Overall 3893 non-duplicate pharyngeal S. pyogenes isolates from outpatients with GAS infection were collected throughout country during 2008 and 2009. Among 486 macrolide resistant pharyngeal isolates collected, 103 were further characterized. Macrolide resistance phenotypes and genotypes were determined by double-disk diffusion test and PCR, respectively. Strain relatedness was determined by emm typing, multilocus sequence typing (MLST), multilocus variable tandem repeat analysis (MLVA), phage profiling (PP) and virulence factor profiling (VFP). Overall, macrolide resistance among GAS isolates in Serbia was 12.5%. M phenotype was the most common (71.8%), followed by iMLS (18.4%) and cMLS (9.7%). Three clonal complexes--emm75/mefA/ST49, emm12/mefA/ST36 and emm77/ermA/tetO/ST63 comprised over 90% of the tested strains. Although MLVA, PP and VFP distinguished 10, 20 and 12 different patterns, respectively, cluster analysis disclosed only small differences between strains which belonged to the same emm/ST type. Our data indicate dominance of three major internationally widely disseminated macrolide resistant clones and a high genetic homogeneity among the Serbian MRGAS population. Continued surveillance of macrolide resistance and clonal composition in MRGAS in Serbia in future is necessary to determine stability of MRGAS clones and to guide therapy strategies. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Epidemiology of group A streptococcal pharyngitis & impetigo: a cross-sectional & follow up study in a rural community of northern India. (United States)

    Kumar, R; Vohra, H; Chakraborty, A; Sharma, Y P; Bandhopadhya, S; Dhanda, V; Sagar, V; Sharma, M; Shah, B; Ganguly, N K


    Group A streptococcus (GAS) causes a wide array of human diseases. Epidemiological picture of streptococcal infection in India is not complete. Hence, disease burden due to GAS in 5-15 yr old school children in northern India was studied and emm typing of GAS isolates was carried out to help in designing prevention strategies. A cross-sectional survey was carried out among 4249 school children (5-15 yr) from Raipur Rani Block of Panchkula district in Haryana during 2000-2002; 334 children were followed up fortnightly for one year. Standard clinical and microbiological procedures were used for collection of swabs from throat and skin and confirmation of GAS and its emm types. Of the 4249 children studied, 658 (15.5%) had pharyngitis; 579 of them could be swabbed, of which 2.8 per cent had GAS. From 3591 children without pharyngitis, 3385 who could be swabbed, GAS was found in 1.3 per cent of them. Impetigo was rare (0.7%), but 7.1 per cent (2/28) children had GAS. In the followup study, 17.4 per cent (776/4447 child-contacts) had pharyngitis, 761 could be swabbed and 2.4 per cent had GAS; among those without pharyngitis, 2016 swabs could be taken and GAS was found in 1.3 per cent; whereas only 2.6 per cent (2/75) of skin sores had GAS. Three children had GAS pharyngitis twice during follow up. Fourteen different GAS emm types were found. emm 71, 77 and 81 constituted 69 per cent of the pharyngeal isolates. GAS pharyngitis and impetigo were more common in winters and summers respectively. In north India, pharyngitis was more common than impetigo. Most prevalent emm types of GAS in this region differ from those included in M protein-based vaccines.

  1. Collection and Analysis of Open Source News for Information Awareness and Early Warning in Nuclear Safeguards

    International Nuclear Information System (INIS)

    Cojazzi, Giacomo G.M.; Van Der Goot, Erik; Verile, Marco; Wolfart, Erik; Rutan Fowler, Marcy; Feldman, Yana; Hammond, William; Schweighardt, John; Ferguson, Mattew


    Acquisition and analysis of open source information plays an increasingly important role in the IAEA’s move towards safeguards implementation based on all safeguards relevant information known about a State. The growing volume of open source information requires the development of technology and tools capable of effectively collecting relevant information, filtering out “noise”, organizing valuable information in a clear and accessible manner, and assessing its relevance. In this context, the IAEA’s Division of Information Management (SGIM) and the EC’s Joint Research Centre (JRC) are currently implementing a joint project to advance the effectiveness and efficiency of the IAEA’s workflow for open source information collection and analysis. The objective is to provide tools to support SGIM in the production of the SGIM Open Source Highlights, which is a daily news brief consisting of the most pertinent news stories relevant to safeguards and non-proliferation. The process involves the review and selection of hundreds of articles from a wide array of specifically selected sources. The joint activity exploits the JRC’s Europe Media Monitor (EMM) and NewsDesk applications: EMM automatically collects and analyses news articles from a pre-defined list of web sites, and NewsDesk allows an analyst to manually select the most relevant articles from the EMM stream for further processing. The paper discusses the IAEA’s workflow for the production of SGIM Open Source Highlights and describes the capabilities of EMM and NewsDesk. It then provides an overview of the joint activities since the project started in 2011, which were focused i) on setting up a separate EMM installation dedicated to the nuclear safeguards and security domain (Nuclear Security Media Monitor, NSMM) and ii) on evaluating the NSMM/NewsDesk for meeting the IAEA’s needs. Finally, it presents the current use NSMM/NewsDesk at the IAEA and proposes options for further integration with the

  2. Development of NUCEF project hereafter

    International Nuclear Information System (INIS)

    Takeshita, Isao; Dojiri, Shigeru


    The construction of NUCEF was started in June, 1989, and it is completed in June, 1994. The hot test is prepared from the middle of this fiscal year, and static critical ficility(STACY)/transient critical facility(TRACY) are expected to attain the initial criticality within this fiscal year. The research plan for the time being was decided, and the conception and policy for the cooperation with outside and utilization are taking shape. In the STACY, low enriched uranium experiment is carried out for about three years, and thereafter, plutonium experiment is started. In the TRACY, the performance is confirmed by raising the test condition, and it is expected to obtain useful data. In the back-end key elements research facility(BECKY), after sufficient uranium experiment, the experiment using actual spent fuel and high level waste liquid is carried out. NUCEF is the facility for carrying out the basic research on the back end of nuclear fuel cycle. The promotion of the national and international cooperation in the research, the contribution to the fostering of capable men, and the method of cooperation with outside are explained. NUCEF has the role of leading the basic research on the safety and the technical advance in this field. (K.I.)

  3. Improvement of neutron source introduction method for absolute measurements of low reactor power

    International Nuclear Information System (INIS)

    Yamamoto, Toshihiro; Miyoshi, Yoshinori


    The neutron source introduction method was applied to absolute measurements of low reactor power at the Static Experiment Critical Facility STACY. To obtain the effective neutron source intensity more accurately, which is a key parameter for the source introduction method, the neutron source is newly defined as fission neutrons from the first fission reaction caused by neutrons emitted from the external neutron source. To obtain the newly defined effective neutron source intensity, the probability that a neutron from the external neutron source causes a fission reaction is calculated using the Monte Carlo code MCNP. This calculation took into consideration the three-dimensional complicated core structures. Furthermore, the fission reaction distribution, fundamental mode forward and adjoint flux distribution in a critical state were calculated using the three-dimensional transport code THREEDANT. Following the principle of the neutron source introduction method, an external neutron source was inserted near the STACY core tank and the reactor power was measured. The reactor powers by the neutron source introduction method were in good agreement with the ones from the analyses of the FP activity generated by high power operation. (author)

  4. Safety research program of NUCEF

    International Nuclear Information System (INIS)

    Naito, Y.


    To contribute the safety and establishment of advanced technologies in the area of nuclear fuel cycle, Japan Atomic Energy Research Institute (JAERI) has constructed a new research facility NUCEF (Nuclear Fuel Cycle Safety Engineering Research Facility) as the center for the research and development, particularly on the reprocessing technology and transuranium (TRU) waste management. NUCEF consist of three buildings, administration building, experiment building A and B. Building A has two experiment facilities STACY (Static Experiment Critical Facility) and TRACY (Transient Experiment Critical Facility). The experiment building B is referred to as BECKY (Back-end Fuel Cycle Key Elements Research Facility). Researches on the reprocessing and the waste management are carried out with spent fuels, high-level liquid waste, TRU etc. in the α γ cell and glove boxes. NUCEF was constructed with the following aims. Using STACY and TRACY, are aimed, (1) research on advanced technology for criticality safety control, (2) reconfirmation of criticality safety margin of the Rokkasho reprocessing plant. Using BECKY, are aimed, (1) research on advanced technology of reprocessing process, (2) contribution to develop the scenario for TRU waste disposal, (3) development of new technology for TRU partitioning and volume reduction of radioactive waste. To realize the above aims, following 5 research subjects are settled in NUCEF, (1) Criticality safety research, (2) Research on safety and advanced technology of fuel reprocessing, (3) Research on TRU waste management, (4) Fundamental research on TRU chemistry, (5) Key technology development for TRU processing. (author)

  5. Scarlet Fever Epidemic in China Caused by Streptococcus pyogenes Serotype M12: Epidemiologic and Molecular Analysis

    Directory of Open Access Journals (Sweden)

    Yuanhai You


    Full Text Available From 2011, Hong Kong and mainland China have witnessed a sharp increase in reported cases, with subsequent reports of epidemic scarlet fever in North Asia and the United Kingdom. Here we examine epidemiological data and investigate the genomic context of the predominantly serotype M12 Streptococcus pyogenes scarlet fever isolates from mainland China. Incident case data was obtained from the Chinese Nationwide Notifiable Infectious Diseases Reporting Information System. The relative risk of scarlet fever in recent outbreak years 2011–2016 was calculated using the median age-standardised incidence rate, compared to years 2003–2010 prior this outbreak. Whole genome sequencing was performed on 32 emm12 scarlet fever isolates and 13 emm12 non-scarlet fever isolates collected from different geographic regions of China, and compared with 203 published emm12 S. pyogenes genomes predominantly from scarlet fever outbreaks in Hong Kong (n = 134 and the United Kingdom (n = 63. We found during the outbreak period (2011–2016, the median age-standardised incidence in China was 4.14/100,000 (95% confidence interval (CI 4.11-4.18, 2.62-fold higher (95% CI 2.57-2.66 than that of 1.58/100,000 (95% CI 1.56-1.61 during the baseline period prior to the outbreak (2003−2010. Highest incidence was reported for children 5 years of age (80.5/100,000. Streptococcal toxin encoding prophage φHKU.vir and φHKU.ssa in addition to the macrolide and tetracycline resistant ICE-emm12 and ICE-HKU397 elements were found amongst mainland China multi-clonal emm12 isolates suggesting a role in selection and expansion of scarlet fever lineages in China. Global dissemination of toxin encoded prophage has played a role in the expansion of scarlet fever emm12 clones. These findings emphasize the role of comprehensive surveillance approaches for monitoring of epidemic human disease.

  6. The molecular epidemiological characteristics of streptococci isolated from primary school children in Vietnam

    Directory of Open Access Journals (Sweden)

    A. G. Nosik


    Full Text Available Objectives. The goal of the study was to isolate group A, С, and G streptococci from children and characterize them by the methods of molecular epidemiology.Materials and methods. Group A, С, and G streptococci were isolated from tonsils and back wall of pharynx of Vietnamese children during 2012–2014. сpn60 gene based PCR approach and rnpB gene sequencing were used to identify streptococcal species belonging to group С and G streptococci. The presence of scpA, lmb, nga, slo virulence genes was analyzed in S. anginosus and S. dysgalactiae subsp. equisimilis strainS. emm-typing of S. pyogenes was done as published ( Antibiotic resistance of the strains was tested by the disk diffusion method.Results. A total of 1359 children were examined. Group A streptococci (S. pyogenes were isolated from 49 children, group C streptococci – from 8 children (4 stains – S. anginosus, 1 strain – S. dysgalactiae subsp. equisimilis, 1 strain – S. parasanguinis, 1 strain – S. gordonii, 1 strain – S. constellatus, and group G streptococci – from 75 children (55 stains – S. anginosus, 8 stains – S. dysgalactiae subsp. equisimilis, 4 stains – S. sanguinis, 3 stains – S. parasanguinis, 2 stains – S. australis, 2 stains – S. constellatus, 1 stain – S. mitis. emm-typing of 47 S. pyogenes strains revealed 15 different emm-subtypes belonging to 11 different emm-typeS. The subtypes emm104.0 and emm109.1 were found to be predominant. S. anginosus strains under study were genetically heterogeneous for the presence of virulence genes. All tested strains were susceptible to cephalosporins and vancomycin, and resistant to amikacine. A total of 70% and 52,5% of S. pyogenes were resistant to tetracycline and erythromycin, respectively.

  7. From Conception to Birth: The Forces Responsible for AFCyber’s Evolution (United States)


    Jason   Healey , “Claiming the Lost Cyber Heritage,” Strategic Studies Quarterly, Fall 2012, 12. Graduate  Research Project, September 2004, 15.  74  Jason   Healey , “Claiming the Lost Cyber Heritage,” Strategic Studies Quarterly, Fall 2012, 12...Environment and the Future of War.” Parameters, Winter 2008-09. Hamre, John. “Interview: Cyber War!” PBS Frontline, 24 April 2003, Healey , Jason

  8. New records of the deep-sea anemone Phelliactis callicyclus Riemann-Zurneck, 1973 (Cnidaria, Actiniaria, Hormathiidae) from the Gulf of California, Mexico. (United States)

    Hendrickx, M E; Hinojosa-Corona, A; Ayón-Parente, M


    Specimens of a deep-sea anemone were observed in photographs and video footage taken with the Remotely Operated Vehicle JASON (WHOI Deep Submergence Laboratory) in the Gulf of California, Mexico, in May 2008. Comparison of our material with photographs and description of this species available in literature indicate that the sea anemones filmed during the JASON survey are most likely to represent Phelliactis callicyclus Riemann-Zurneck, 1973. This species has previously been reported from a locality in the Gulf of California near the present record. During the JASON survey, 28 specimens of P. callicyclus were spotted in 27 locations during six dives. The specimens occurred on angular rock outcrops along the escarpments of the transform faults of the Gulf of California, between depths of 993-2543 m and at temperatures ranging from 2.3 to 4.5°C. Based on these new records, Phelliactis callicyclus appears to be widely spread in the Gulf of California.

  9. Climate-change-driven accelerated sea-level rise detected in the altimeter era. (United States)

    Nerem, R S; Beckley, B D; Fasullo, J T; Hamlington, B D; Masters, D; Mitchum, G T


    Using a 25-y time series of precision satellite altimeter data from TOPEX/Poseidon, Jason-1, Jason-2, and Jason-3, we estimate the climate-change-driven acceleration of global mean sea level over the last 25 y to be 0.084 ± 0.025 mm/y 2 Coupled with the average climate-change-driven rate of sea level rise over these same 25 y of 2.9 mm/y, simple extrapolation of the quadratic implies global mean sea level could rise 65 ± 12 cm by 2100 compared with 2005, roughly in agreement with the Intergovernmental Panel on Climate Change (IPCC) 5th Assessment Report (AR5) model projections. Copyright © 2018 the Author(s). Published by PNAS.

  10. Multi-Satellite Altimeter Validation along the French Atlantic Coast in the Southern Bay of Biscay from ERS-2 to SARAL

    Directory of Open Access Journals (Sweden)

    Phuong Lan Vu


    Full Text Available Monitoring changes in coastal sea levels is necessary given the impacts of climate change. Information on the sea level and its changes are important parameters in connection to climate change processes. In this study, radar altimetry data from successive satellite missions, European Remote Sensing-2 (ERS-2, Jason-1, Envisat, Jason-2, and Satellite with ARgos and ALtiKa (SARAL, were used to measure sea surface heights (SSH. Altimetry-derived SSH was validated for the southern Bay of Biscay, using records from seven tide gauges located along the French Atlantic coast. More detailed comparisons were performed at La Rochelle, as this was the only tide gauge whose records covered the entire observation period for the different radar altimetry missions. The results of the comparison between the altimetry-based and in-situ SSH, recorded from zero to five kilometers away from the coast, had root mean square errors (RMSE ranging from 0.08 m to 0.21 m, 0.17 m to 0.34 m, 0.1 m to 0.29 m, 0.18 m to 0.9 m, and 0.22 m to 0.89 m for SARAL, Jason-2, Jason-1, ENVISAT, and ERS-2, respectively. Comparing the missions on the same orbit, ENVISAT had better results than ERS-2, which can be accounted for by the improvements in the sensor mode of operation, whereas the better results obtained using SARAL are related to the first-time use of the Ka-band for an altimetry sensor. For Jason-1 and Jason-2, improvements were found in the ocean retracking algorithm (MLE-4 against MLE-3, and also in the bi-frequency ionosphere and radiometer wet troposphere corrections. Close to the shore, the use of model-based ionosphere (GIM and wet troposphere (ECMWF corrections, as applied to land surfaces, reduced the error on the SSH estimates.

  11. SH wave propagation in joined half-spaces composed of elastic metamaterials (United States)

    Shi, Xiaona; Shu, Haisheng; Zhou, Haiyong; Zhao, Lei; Liu, Ru; An, Shuowei; Zhu, Jie


    Based on the effective-medium theory, the propagation of a shear horizontal (SH) wave in joined half-spaces composed of elastic metamaterials (EMMs) is investigated. From the dispersion relations, the effects of negative effective-medium parameters on the properties of a SH wave traveling near the interface are analyzed in detail. It is found that a SH wave can always appear and travel along the interface under specific effective-parameter combinations no matter whether the effective transverse wave velocity is imaginary or real. This is significantly different from the classical case (joined half-spaces composed of natural media), and the existence of these SH interfacial wave modes may have important impacts on EMM-based SH wave manipulation, especially wave isolation and object protection.

  12. Teaching nanoscience across scientific and geographical borders - A European Master programme in nanoscience and nanotechnology

    International Nuclear Information System (INIS)

    Chesneau, A; Schwille, P; Groeseneken, G; Heremans, P; Rep, D; Rudquist, P; Wendin, G; Sluijter, B


    Within the Erasmus Mundus Master (EMM) Programme, five European Universities (KU Leuven, Belgium, Chalmers University of Technology, Sweden, Delft University of Technology and Leiden University, the Netherlands, and the University of Dresden, Germany) have joined forces to offer a unique master programme in Nanoscience and Nanotechnology, 'EMM-nano', at the cutting edge of state-of-the-art research. The students design and build their individual area of specialisation within nanophysics, nanotechnology, biophysics, biotechnology through their choice of trajectory between the partners. We discuss some of the challenges related to the crossdisciplinary nature of the field, educational activities in cleanrooms, and issues related to the integration of teaching programmes across the borders within Europe

  13. Ergonomic sustainability based on the ergonomic maturity level measurement. (United States)

    Vidal, Mario Cesar; Guizze, Carmen Lucia Campos; Bonfatti, Renato José; Silva e Santos, Marcello


    This paper aims at the application of an ergonomic maturity model (EMM), in order to assess the ergonomic sustainability outreach of ergonomic actions. This proposition was motivated by the widespread sensation that the development of the discipline, its educational devices and related practices depends on the attitude of ergonomics practitioners rather than environmental macroergonomic conditions. Maturity modeling in this paper is undertaken as a tool for ergonomic practitioners. Thus, its foundations were uprooted from diverse fields: Clinic Psychology, Quality Management and Project Management. The paper brings about a detailled explanation of this ergonomic maturity tool. The empirical part is fulfilled by the examination - using the EMM - of four emblematic cases excerpted from our research lab ergonomic portfolio.

  14. Infrastructuring and Ordering Devices in Health Care

    DEFF Research Database (Denmark)

    Markussen, Randi; Bossen, Claus


    and more channels through which coordination among distributed actors is enabled and formed. In this case, infrastructuring means an extended scope and intensity of the coordinative capabilities of medication plans, and an increased vulnerability to, and dependency on events outside the immediate loci......In this paper, we analyse physicians' and nurses' practices of prescribing and administering medication through the use of paper-based, and digitalized medication plans. Our point of departure is an ethnographic study of the implications of upgrading an electronic medication module (EMM......) that is part of an electronic health record (EHR), carried out at an endocrinology department. The upgrade led to a temporary breakdown of the EMM, and a return to paper-based medication plans. The breakdown made visible and noticeable the taken-for-granted capabilities of medication plans in their paper...

  15. [Carriage of Streptococcus pyogenes in primary school children: M-protein types, pyrogenic toxin genes, and investigation of the clonal relationships between the isolates]. (United States)

    Otlu, Barış; Karakurt, Cemşit; Bayındır, Yaşar; Kayabaş, Üner; Yakupoğulları, Yusuf; Gözükara Bağ, Harika


    M-protein and pyrogenic toxins are the most important virulence factors of Streptococcus pyogenes, and they play significant role in the pathophysiology of acute rheumatoid fever and scarlet fever, respectively. In this study, the pharyngeal carriage of S.pyogenes of the primary school children, clonal relationship of the strains, M-protein types, and the presence of pyrogenic toxin genes were aimed to be investigated. A total of 668 throat cultures obtained from children (age range: 6-16 years) in two primary schools in our region, were included in the study. The clonal relationships of the isolated group A streptococci (GAS) strains were investigated by DiversiLab assay (BioMérieux, France), and the clonal relatedness was confirmed by pulsed-field gel electrophoresis (PFGE) method. M-protein (emm) typing was performed by DNA sequencing as suggested by Centers for Disease Control and Prevention (CDC). The genes encoding pyrogenic toxins, speA and speC, were investigated by an in-house multiplex polymerase chain reaction (PCR) method. S.pyogenes was isolated from 134 (20.05%) of the throat samples. The GAS carriage rate of the students aged ≥10 was statistically higher than those 7-9 years age group (%22 vs %16.4, pprotein gene could be characterized only among 123 isolates by DNA sequencing, and 20 different emm types were detected. The most frequent emm type was emm1 (n=38, 30.9%) followed by emm12 (n=18, 14.6%), emm89 (n=10, 8.1%), emm118 (n=9, 7.3%), and emm4 (n=7, 5.7%). Pyrogenic toxin genes were found in 25 (18.6%) of the isolates, including speA in 11 isolates (8.2%) and speC in 12 isolates (8.9%) and both genes were detected in 2 isolates (1.5%). Sixty-two different Rep (Repetitive extragenic palindromic)-PCR profiles were detected in 134 S.pyogenes isolates by DiversiLab method. Thirteen different clusters were formed by a total of clonally related 36 isolates revealing a strain clustering ratio of 26.9%. Clonal relationship of all isolates in the same

  16. An Approach toward an Asia-Pacific Strategy 2012 to 2020 (United States)


    of Chaos,” Foreign Affairs 89, no. 2 (March/April 2010): 18–32. 23. J. R. Wu and Jason Dean, “Wen Engages Web Users in Rare Web Chat,” Wall Street...Points (New York: Lehman Brothers, 18 January 2008), http://www 8. Jason Szep, “Burma Gas Pipeline...has rejoined the Coast Guard’s fleet, complementing the medium icebreaker Healey , thus changing this equation. 18. A United Press International (UPI

  17. Progressively Communicating Rich Telemetry from Autonomous Underwater Vehicles via Relays (United States)


    like the JASON II[31] or Nereus[12] Remotely Operated Vehicles (ROVs), AUV sensor data is typically inaccessible until after the vehicle has been...Bowen, M. Heintz, M. Naiman, C. Taylor, W. Seller, J.C. How- land, and L.L. Whitcomb. Jason 2: a review of capabilities. In EOS: Trans. Amer...Sousa, M. Correia, H. Ferreira, R. Goncalves, R. Martins, D.P. Horner, A.J. Healey , G.M. Goncalves, and J.B. Sousa. AUV control and communication

  18. Optimizing Hyperspectral Imagery Anomaly Detection through Robust Parameter Design (United States)


    appreciated as well as all of the other members of the ENS department. Finally, to the OR crew, Jacob, Earl, Tiffany, Jason , Jeremy, Steve, Ben and...Technology , 41 :631–641 (2009). 10.1007/s00170-008-1509-2. [74] Shi, M and G. Healey . “Using multiband correlation models for the invari- ant...matching methods. Dissertation, Air Force Institute of Technology (AU),Wright-Patterson AFB, OH, June 2007. AFIT/DS/ENS/07-07. Williams, Jason P

  19. Real Science, Real Learning: Bridging the Gap Between Scientists, Educators and Students (United States)

    Lewis, Y.


    Today as never before, America needs its citizens to be literate in science and technology. Not only must we only inspire a new generation of scientists and engineers and technologists, we must foster a society capable of meeting complex, 21st-century challenges. Unfortunately, the need for creative, flexible thinkers is growing at a time when our young students are lagging in science interest and performance. Over the past 17 years, the JASON Project has worked to link real science and scientists to the classroom. This link provide viable pipeline to creating the next generation scientists and researchers. Ultimately, JASON's mission is to improve the way science is taught by enabling students to learn directly from leading scientists. Through partnerships with agencies such as NOAA and NASA, JASON creates multimedia classroom products based on current scientific research. Broadcasts of science expeditions, hosted by leading researchers, are coupled with classroom materials that include interactive computer-based simulations, video- on-demand, inquiry-based experiments and activities, and print materials for students and teachers. A "gated" Web site hosts online resources and provides a secure platform to network with scientists and other classrooms in a nationwide community of learners. Each curriculum is organized around a specific theme for a comprehensive learning experience. It may be taught as a complete package, or individual components can be selected to teach specific, standards-based concepts. Such thematic units include: Disappearing Wetlands, Mysteries of Earth and Mars, and Monster Storms. All JASON curriculum units are grounded in "inquiry-based learning." The highly interactive curriculum will enable students to access current, real-world scientific research and employ the scientific method through reflection, investigation, identification of problems, sharing of data, and forming and testing hypotheses. JASON specializes in effectively applying

  20. Game engine architecture

    CERN Document Server

    Gregory, Jason


    ""… this book is the best of its kind, and you're lucky to have found it. It covers the huge field of game engine architecture in a succinct, clear way, and expertly balances the breadth and depth of its coverage, offering enough detail that even a beginner can easily understand the concepts it presents. The author, Jason Gregory, is not only a world expert in his field; he's a working programmer with production-quality knowledge and many shipped game projects under his belt. … Jason is also an experienced educator who has taught in the top-ranked university game program in North America. …

  1. Auto-fiction and Identity in Esther Tusquets’ Trilogy


    Dobianer, Nicole


    This thesis investigates personal development and identity formation in Esther Tusquets and the female protagonists in her trilogy, composed of El mismo mar de todos los veranos (EMM) (1978), El amor es un juego solitario (AJS) (1979) and Varada tras el último naufragio (VUN) (1980). \\ud Recent autobiographic publications had made it possible to shed light on the author behind the literature and had provided indications that supported a hypothesis of life influencing literature.\\ud This thesi...

  2. Genève explore le centre de l'univers le CERN nourrit les espoirs des physiciens

    CERN Multimedia

    Koller, A


    "Si Albert Einstein vivait encore, il emménagerait sans doute à Genève ou en France voisine, au moins pour les quinze prochaines années. Moins pour célébrer dès aujourd'hui les 50 ans du CERN que pour travailler dès 2007 avec le Large hadron Collder (LHC)"(1/2 page)

  3. Browse Title Index

    African Journals Online (AJOL)

    (Nord-Ouest du Maroc), Abstract PDF .... Vol 3, No 6 (2009), Etude ethnobotanique des plantes galactogènes et emménagogues utilisées dans les terroirs riverains à la Zone Cynégétique de la ... Vol 7, No 2 (2013), Evaluation in vitro de l'activité antifalcémiante et effet antioxydant des extraits d'Uapaca heudelotii Baill.

  4. Invasive Group A Streptococcal Infection and Vaccine Implications, Auckland, New Zealand


    Safar, Atheer; Lennon, Diana; Stewart, Joanna; Trenholme, Adrian; Drinkovic, Dragana; Peat, Briar; Taylor, Susan; Read, Kerry; Roberts, Sally; Voss, Lesley


    We aimed to assess the effect of invasive group A streptococcal (GAS) infection and the potential effects of a multivalent GAS vaccine in New Zealand. During January 2005–December 2006, we conducted prospective population-based laboratory surveillance of Auckland residents admitted to all public hospitals with isolation of GAS from normally sterile sites. Using emm typing, we identified 225 persons with confirmed invasive GAS infection (median 53 years of age; range 0–97 years). Overall incid...

  5. Development of electromagnetic and piezoelectric hybrid actuator system


    OKEYA, Ryota; AOYAGI, Manabu; TAKANO, Takehiro; TAMURA, Hideki


    An ordinal force-feedback device typically uses an electromagnetic motor (EMM), which provides an excellent expression of elasticity. However, it is not easy to express the sense of hardness and roughness because the response of the current is delayed due to the inductance of the armature winding. On the contrary, a piezoelectric actuator, which has a rapid response, is good at expressing the sense of hardness and roughness. Thus, if different types of actuators are used in the same actuator ...

  6. An ultrasonic actuator with built in clutch mechanism(No.5)Trial hybrid composition with electromagnetic motor


    桶谷, 涼太; 青柳, 学; 高野, 剛浩; 田村, 英樹


    It is difficult for the ultrasonic motor to change the preload while driving. Then, an ultrasonic actuator that was able to electrically control a preload was developed by combining piezoelectric motor with clutch function in this study. In this paper, a hybrid actuator system combining an electromagnetic motor (EMM) with a piezoelectric motor was proposed and examined. The driving range can be widened by combining the both actuators with a different characteristic. As one of results, a riset...

  7. doi:10.21010/ajtcam.v14i2.11

    African Journals Online (AJOL)


    of 25 ± 3°C, relative humidity of 35 to 60%. They were given Harlan food and water ad libitum until the end of the experiment. Six ..... Bastos, M.L.A., M.R.F. Lima, L.M. Conserva, V.S. Andrade, E.M.M. Rocha and R.P.L. Lemos. (2009). Studies on the antimicrobial activity and brine shrimp toxicity of Zeyheriatuberculosa (Vell.) ...

  8. Evaluation of the WavTrac Expeditionary Mobility Matting System (United States)


    California Bearing Ratio (CBR) of 15 percent. 2. The EMMS must support a minimum of 500 passes of a 7-ton MTVR truck loaded to its off-road payload...scale test section construction The full-scale test sections described in this report are defined in terms of their subgrade type and California Bearing ... Ratio (CBR). The following definitions will be used to describe the subgrade conditions investigated in this report: • SP-15: loose sand test

  9. Product Manager Combat Engineering and Material Handling Equipment (United States)


    Asphalt Mixing Plant  Skid Steer Loader Type 2 & 3  EMM Water Distributor  Hasty Road Repair  Soil Density Tester  Vibratory Plate Compactor...Engineer/Material Handling Equipment  Eng Rapid Airfield Cont Capability IV  Bituminous Paving Machine  Type 2 Heavy ATEC  Water Well Drill Rig...maneuver support, enable theater access, assured mobility, and airstrip/airfield construction . The FOD also provides earthmoving operational capabilities

  10. Author Details

    African Journals Online (AJOL)

    Etude phytochimique des principales plantes galactogènes et emménagogues utilisées dans les terroirs riverains de la Zone cynégétique de la Pendjari Abstract PDF · Vol 5, No 3 (2011) - Articles Facteurs déterminant la variabilité spatiale de la biomasse herbacée dans la zone soudano-guinéenne du Bénin Abstract PDF ...

  11. Luck Is Not a Strategy: Inefficient Coercion In Operation Allied Force (United States)


    the European War,” in Emme, Impact of Air Power, 228–29. 12 5. Independent Strike Doctrine Today Based on decades of experience and technological...1,500 deaths and left hundreds of thousands homeless ; in response, NATO threatened an air campaign similar to the previous Deliberate Force if a...89 Matthew Kaminski and John Reed, “NATO Link to KLA Rebels May Have Helped Seal Victory,” Wall Street Journal , July 6, 1999,

  12. Distribution of small native plasmids in Streptococcus pyogenes in India. (United States)

    Bergmann, René; Nerlich, Andreas; Chhatwal, Gursharan S; Nitsche-Schmitz, D Patric


    Complete characterization of a Streptococcus pyogenes population from a defined geographic region comprises information on the plasmids that circulate in these bacteria. Therefore, we determined the distribution of small plasmids (pyogenes isolates from India, where diversity of strains and incidence rates of S. pyogenes infections are high. The collection comprised 77 emm-types. For plasmid detection and discrimination, we developed PCRs for different plasmid replication initiation protein genes, the putative repressor gene copG and bacteriocin genes dysA and scnM57. Plasmid distribution was limited to 13 emm-types. Co-detection analysis using aforementioned PCRs revealed four distinct plasmid sub-types, two of which were previously unknown. Representative plasmids pA852 and pA996 of the two uncharacterized plasmid sub-types were sequenced. These two plasmids could be assigned to the pMV158 and the pC194/pUB110 family of rolling-circle plasmids, respectively. The majority of small plasmids found in India belonged to the two newly characterized sub-types, with pA852- and pA996-like plasmids amounting to 42% and 22% of all detected plasmids, respectively. None of the detected plasmids coded for a known antibiotic resistance gene. Instead, all of the four plasmid sub-types carried known or potential bacteriocin genes. These genes may have influence on the evolutionary success of certain S. pyogenes genotypes. Notably, pA852-like plasmids were found in all isolates of the most prevalent emm-type 11.0. Together, a priori fitness of this genotype and increased fitness due to the acquired plasmids may have rendered type emm11.0 successful and caused the prevalence of pA852-like plasmids in India. Copyright © 2013 Elsevier GmbH. All rights reserved.

  13. Recurrent bacteremia with different strains of Streptococcus pyogenes in an immunocompromised child. (United States)

    Hattori, Takuya; Minami, Masaaki; Narita, Kotaro; Nakata, Tomohiko; Itomi, Seiko; Kubota, Kinya; Oya, Teruaki; Nishiyama, Hideki; Kato, Hideki; Yuasa, Norihiro


    We report an immunocompromised child who experienced two episodes of bacteremia due to Streptococcus pyogenes. Random amplification of polymorphic DNA profiles, emm genotypes, superantigen profiles, antimicrobial susceptibility, and resistance-related genes were investigated, and the results showed different profiles between the two isolates. This is the first report describing recurrent bacteremia caused by different strains of S. pyogenes. Copyright © 2016 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  14. 1017-IJBCS-Article-Ines Edna Deleke Koko

    African Journals Online (AJOL)


    La présente étude réalisée sur les plantes emménagogues et galactogènes utilisées dans les terroirs riverains de la Zone Cynégétique de la Pendjari a pour objectif de caractériser les groupes de substances chimiques contenus dans les drogues végétales utilisées pour le traitement traditionnel des troubles menstruels.

  15. Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes. (United States)

    Saslow, Laura R; Daubenmier, Jennifer J; Moskowitz, Judith T; Kim, Sarah; Murphy, Elizabeth J; Phinney, Stephen D; Ploutz-Snyder, Robert; Goldman, Veronica; Cox, Rachel M; Mason, Ashley E; Moran, Patricia; Hecht, Frederick M


    Dietary treatment is important in management of type 2 diabetes or prediabetes, but uncertainty exists about the optimal diet. We randomized adults (n = 34) with glycated hemoglobin (HbA1c) > 6.0% and elevated body weight (BMI > 25) to a very low-carbohydrate ketogenic (LCK) diet (n = 16) or a moderate-carbohydrate, calorie-restricted, low-fat (MCCR) diet (n = 18). All participants were encouraged to be physically active, get sufficient sleep, and practice behavioral adherence strategies based on positive affect and mindful eating. At 12 months, participants in the LCK group had greater reductions in HbA1c levels (estimated marginal mean (EMM) at baseline = 6.6%, at 12 mos = 6.1%) than participants in MCCR group (EMM at baseline = 6.9%, at 12 mos = 6.7%), p = .007. Participants in the LCK group lost more weight (EMM at baseline = 99.9 kg, at 12 mos = 92.0 kg) than participants in the MCCR group (EMM at baseline = 97.5 kg, at 12 mos = 95.8 kg), p diabetes-related medication use; of participants who took sulfonylureas or dipeptidyl peptidase-4 inhibitors at baseline, 6/10 in the LCK group discontinued these medications compared with 0/6 in the MCCR group (p = .005). In a 12-month trial, adults with elevated HbA1c and body weight assigned to an LCK diet had greater reductions in HbA1c, lost more weight, and reduced more medications than those instructed to follow an MCCR diet.

  16. AcEST: BP913956 [AcEST

    Lifescience Database Archive (English)

    Full Text Available s musculus GN=Poli... 30 7.3 sp|Q8EMM9|KDUI_OCEIH 4-deoxy-L-threo-5-hexosulose-uronate ketol-... 30 9.4 sp|Q9VDW6|DMDA_DROME, isoforms A/C/F/G/H OS=Drosophil... 30 9.4 sp|Q09744|YB63_SCHPO Uncharacterized

  17. Antifungal Activity, Toxicity and Chemical Composition of the Essential Oil of Coriandrum sativum L. Fruits

    Directory of Open Access Journals (Sweden)

    Erika H. S. Brito


    Full Text Available The aims of this study were to test the antifungal activity, toxicity and chemical composition of essential oil from C. sativum L. fruits. The essential oil, obtained by hydro-distillation, was analyzed by gas chromatography/mass spectroscopy. Linalool was the main constituent (58.22%. The oil was considered bioactive, showing an LC50 value of 23 µg/mL in the Artemia salina lethality test. The antifungal activity was evaluated against Microsporum canis and Candida spp. by the agar-well diffusion method and the minimum inhibitory concentration (MIC and the minimum fungicidal concentration (MFC were established by the broth microdilution method. The essential oil induced growth inhibition zones of 28 ± 5.42 and 9.25 ± 0.5 for <em>M. canis and Candida spp. respectively. The MICs and MFCs for <em>M. canis strains ranged from 78 to 620 and 150 to 1,250 µg/mL, and the MICs and MFCs for Candida spp strains ranged from 310 to 620 and 620 to 1,250 µg/mL, respectively. C. sativum essential oil is active in vitro against <em>M. canis and Candida spp. demonstrating good antifungal activity.

  18. On the role of tropopause folds in summertime tropospheric ozone over the eastern Mediterranean and the Middle East (United States)

    Akritidis, Dimitris; Pozzer, Andrea; Zanis, Prodromos; Tyrlis, Evangelos; Škerlak, Bojan; Sprenger, Michael; Lelieveld, Jos


    We study the contribution of tropopause folds in the summertime pool of tropospheric ozone over the eastern Mediterranean and the Middle East (EMME) with the aid of the ECHAM5/MESSy Atmospheric Chemistry (EMAC) model. Tropopause fold events in EMAC simulations were identified with a 3-D labeling algorithm that detects folds at grid points where multiple crossings of the dynamical tropopause are computed. Subsequently the events featuring the largest horizontal and vertical extent were selected for further study. For the selection of these events we identified a significant contribution of the stratospheric ozone reservoir to the high concentrations of ozone in the middle and lower free troposphere over the EMME. A distinct increase of ozone is found over the EMME in the middle troposphere during summer as a result of the fold activity, shifting towards the southeast and decreasing altitude. We find that the interannual variability of near-surface ozone over the eastern Mediterranean (EM) during summer is related to that of both tropopause folds and ozone in the free troposphere.

  19. Molecular typing of Chinese Streptococcus pyogenes isolates. (United States)

    You, Yuanhai; Wang, Haibin; Bi, Zhenwang; Walker, Mark; Peng, Xianhui; Hu, Bin; Zhou, Haijian; Song, Yanyan; Tao, Xiaoxia; Kou, Zengqiang; Meng, Fanliang; Zhang, Menghan; Bi, Zhenqiang; Luo, Fengji; Zhang, Jianzhong


    Streptococcus pyogenes causes human infections ranging from mild pharyngitis and impetigo to serious diseases including necrotizing fasciitis and streptococcal toxic shock syndrome. The objective of this study was to compare molecular emm typing and pulsed field gel electrophoresis (PFGE) with multiple-locus variable-number tandem-repeat analysis (MLVA) for genotyping of Chinese S. pyogenes isolates. Molecular emm typing and PFGE were performed using standard protocols. Seven variable number tandem repeat (VNTR) loci reported in a previous study were used to genotype 169 S. pyogenes geographically-diverse isolates from China isolated from a variety of disease syndromes. Multiple-locus variable-number tandem-repeat analysis provided greater discrimination between isolates when compared to emm typing and PFGE. Removal of a single VNTR locus (Spy2) reduced the sensitivity by only 0.7%, which suggests that Spy2 was not informative for the isolates screened. The results presented support the use of MLVA as a powerful epidemiological tool for genotyping S. pyogenes clinical isolates. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Comparative pathogenomic characterization of a non-invasive serotype M71 strain Streptococcus pyogenes NS53 reveals incongruent phenotypic implications from distinct genotypic markers. (United States)

    Bao, Yun-Juan; Li, Yang; Liang, Zhong; Agrahari, Garima; Lee, Shaun W; Ploplis, Victoria A; Castellino, Francis J


    The strains serotyped as M71 from group A Streptococcus are common causes of pharyngeal and skin diseases worldwide. Here we characterize the genome of a unique non-invasive M71 human isolate, NS53. The genome does not contain structural rearrangements or large-scale gene gains/losses, but encodes a full set of non-truncated known virulence factors, thus providing an ideal reference for comparative studies. However, the NS53 genome showed incongruent phenotypic implications from distinct genotypic markers. NS53 is characterized as an emm pattern D and FCT (fibronectin-collagen-T antigen) type-3 strain, typical of skin tropic strains, but is phylogenetically close to emm pattern E strains with preference for both skin and pharyngeal infections. We propose that this incongruence could result from recombination within the emm gene locus, or, alternatively, selection has been against those genetic alterations. Combined with the inability to select for CovS switching, a process is indicated whereby NS53 has been pre-adapted to specific host niches selecting against variations in CovS and many other genes. This may allow the strain to attain successful colonization and long-term survival. A balance between genetic variations and fitness may exist for this bacterium to form a stabilized genome optimized for survival in specific host environments. © FEMS 2017. All rights reserved. For permissions, please e-mail:

  1. Effect of electro-acupuncture, massage, mud, and sauna therapies in patient with rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Geetha B Shetty


    Full Text Available A 48-year-old married woman diagnosed with rheumatoid arthritis (RA in 2007, came to our hospital in July 2014 with the complaint of severe pain and swelling over multiple joints, especially over small joints, which was associated with stiffness (more in morning, deformities of fingers and toes, with disturbed sleep and poor quality of life (QOL for the past 7 years. She received a combination of electro acupuncture (14 sessions, massage (18 sessions, mud (18 sessions, and sauna (3 sessions (EMMS therapies for 30-min, 45-min, 30-min, and 15-min per session, respectively for 3 weeks. During and postintervention assessment showed reduction in visual analog scale score for pain, Depression Anxiety and Stress Scales and the Pittsburgh Sleep Quality Index scores. It also showed an increase in the scores of 10-Meter Walk Test, isometric hand-grip test, and short form-36 version-2 health survey. This result suggest that, the EMMS therapy might be considered as an effective treatments in reducing pain, depression, anxiety, and stress with improvement in physical functions, quality of sleep and QOL in patient with RA. EMMS therapies were tolerated and no side effects were reported by the patient. Though the results are encouraging, further studies are required with larger sample size and advanced inflammatory markers.

  2. Adaptive root foraging strategies along a boreal-temperate forest gradient. (United States)

    Ostonen, Ivika; Truu, Marika; Helmisaari, Heljä-Sisko; Lukac, Martin; Borken, Werner; Vanguelova, Elena; Godbold, Douglas L; Lõhmus, Krista; Zang, Ulrich; Tedersoo, Leho; Preem, Jens-Konrad; Rosenvald, Katrin; Aosaar, Jürgen; Armolaitis, Kęstutis; Frey, Jane; Kabral, Naima; Kukumägi, Mai; Leppälammi-Kujansuu, Jaana; Lindroos, Antti-Jussi; Merilä, Päivi; Napa, Ülle; Nöjd, Pekka; Parts, Kaarin; Uri, Veiko; Varik, Mats; Truu, Jaak


    The tree root-mycorhizosphere plays a key role in resource uptake, but also in the adaptation of forests to changing environments. The adaptive foraging mechanisms of ectomycorrhizal (EcM) and fine roots of Picea abies, Pinus sylvestris and Betula pendula were evaluated along a gradient from temperate to subarctic boreal forest (38 sites between latitudes 48°N and 69°N) in Europe. Variables describing tree resource uptake structures and processes (absorptive fine root biomass and morphology, nitrogen (N) concentration in absorptive roots, extramatrical mycelium (EMM) biomass, community structure of root-associated EcM fungi, soil and rhizosphere bacteria) were used to analyse relationships between root system functional traits and climate, soil and stand characteristics. Absorptive fine root biomass per stand basal area increased significantly from temperate to boreal forests, coinciding with longer and thinner root tips with higher tissue density, smaller EMM biomass per root length and a shift in soil microbial community structure. The soil carbon (C) : N ratio was found to explain most of the variability in absorptive fine root and EMM biomass, root tissue density, N concentration and rhizosphere bacterial community structure. We suggest a concept of absorptive fine root foraging strategies involving both qualitative and quantitative changes in the root-mycorrhiza-bacteria continuum along climate and soil C : N gradients. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  3. Ricerche sugli enterobatteri nelle feci di Chirotteri

    Directory of Open Access Journals (Sweden)

    Dino Scaravelli


    Full Text Available Dal 2002, grazie al protocollo stipulato tra il gruppo di studio chirotteri del Museo di Onferno e l?Istituto Zooprofilattico Sperimentale della Lombardia e dell?Emilia, sezione di Forlì, si è iniziato un progetto di studio sulla enteroflora di varie specie di Chirotteri. I campioni fecali o più raramente da carcassa, sono stati procssati mediante sistemi standardizzati e tipizzati mediante Enterotubes, creando anche una collezione di riferimento. Le ricerche ad oggi hanno interessato campioni provenienti da diverse regioni e da un certo pool di specie: Myotis daubentonii, <em>M. blythii, <em>M. myotis, Miniopterus schreibersii, Nyctalus noctula, Pipistrellus kuhlii, Rhinolophus ferrumequinum, R. hipposideros. Non sono stati mai identificati vettori di zoonosi o altri batteri che siano di alcun interesse per la salute umana, mentre si descrivono qui alcune specie nuove per la fauna italiana in relazione ai Chirotteri quali Providencia alcalifaciens in N.noctula, Serratia marcescens in <em>M. schreibersii e Klebsiella oezaenale in R. hipposideros. Il lavoro invita inoltre ad una maggiore collaborazione e a stringere accordi per ampliare la possibile raccolta dei campioni.

  4. Stepped-wedge cluster randomised controlled trial to assess the effectiveness of an electronic medication management system to reduce medication errors, adverse drug events and average length of stay at two paediatric hospitals: a study protocol. (United States)

    Westbrook, J I; Li, L; Raban, M Z; Baysari, M T; Mumford, V; Prgomet, M; Georgiou, A; Kim, T; Lake, R; McCullagh, C; Dalla-Pozza, L; Karnon, J; O'Brien, T A; Ambler, G; Day, R; Cowell, C T; Gazarian, M; Worthington, R; Lehmann, C U; White, L; Barbaric, D; Gardo, A; Kelly, M; Kennedy, P


    Medication errors are the most frequent cause of preventable harm in hospitals. Medication management in paediatric patients is particularly complex and consequently potential for harms are greater than in adults. Electronic medication management (eMM) systems are heralded as a highly effective intervention to reduce adverse drug events (ADEs), yet internationally evidence of their effectiveness in paediatric populations is limited. This study will assess the effectiveness of an eMM system to reduce medication errors, ADEs and length of stay (LOS). The study will also investigate system impact on clinical work processes. A stepped-wedge cluster randomised controlled trial (SWCRCT) will measure changes pre-eMM and post-eMM system implementation in prescribing and medication administration error (MAE) rates, potential and actual ADEs, and average LOS. In stage 1, 8 wards within the first paediatric hospital will be randomised to receive the eMM system 1 week apart. In stage 2, the second paediatric hospital will randomise implementation of a modified eMM and outcomes will be assessed. Prescribing errors will be identified through record reviews, and MAEs through direct observation of nurses and record reviews. Actual and potential severity will be assigned. Outcomes will be assessed at the patient-level using mixed models, taking into account correlation of admissions within wards and multiple admissions for the same patient, with adjustment for potential confounders. Interviews and direct observation of clinicians will investigate the effects of the system on workflow. Data from site 1 will be used to develop improvements in the eMM and implemented at site 2, where the SWCRCT design will be repeated (stage 2). The research has been approved by the Human Research Ethics Committee of the Sydney Children's Hospitals Network and Macquarie University. Results will be reported through academic journals and seminar and conference presentations. Australian New Zealand

  5. Whole genome sequencing of group A Streptococcus: development and evaluation of an automated pipeline for emmgene typing

    Directory of Open Access Journals (Sweden)

    Georgia Kapatai


    Full Text Available Streptococcus pyogenes group A Streptococcus (GAS is the most common cause of bacterial throat infections, and can cause mild to severe skin and soft tissue infections, including impetigo, erysipelas, necrotizing fasciitis, as well as systemic and fatal infections including septicaemia and meningitis. Estimated annual incidence for invasive group A streptococcal infection (iGAS in industrialised countries is approximately three per 100,000 per year. Typing is currently used in England and Wales to monitor bacterial strains of S. pyogenes causing invasive infections and those isolated from patients and healthcare/care workers in cluster and outbreak situations. Sequence analysis of the emm gene is the currently accepted gold standard methodology for GAS typing. A comprehensive database of emm types observed from superficial and invasive GAS strains from England and Wales informs outbreak control teams during investigations. Each year the Bacterial Reference Department, Public Health England (PHE receives approximately 3,000 GAS isolates from England and Wales. In April 2014 the Bacterial Reference Department, PHE began genomic sequencing of referred S. pyogenes isolates and those pertaining to selected elderly/nursing care or maternity clusters from 2010 to inform future reference services and outbreak analysis (n = 3, 047. In line with the modernizing strategy of PHE, we developed a novel bioinformatics pipeline that can predict emmtypes using whole genome sequence (WGS data. The efficiency of this method was measured by comparing the emmtype assigned by this method against the result from the current gold standard methodology; concordance to emmsubtype level was observed in 93.8% (2,852/3,040 of our cases, whereas in 2.4% (n = 72 of our cases concordance was observed to emm type level. The remaining 3.8% (n = 117 of our cases corresponded to novel types/subtypes, contamination, laboratory sample transcription errors or problems arising

  6. Devolution and its effects on health workforce and commodities management - early implementation experiences in Kilifi County, Kenya. (United States)

    Tsofa, Benjamin; Goodman, Catherine; Gilson, Lucy; Molyneux, Sassy


    Decentralisation is argued to promote community participation, accountability, technical efficiency, and equity in the management of resources, and has been a recurring theme in health system reforms for several decades. In 2010, Kenya passed a new constitution that introduced 47 semi-autonomous county governments, with substantial transfer of responsibility for health service delivery from the central government to these counties. Focusing on two key elements of the health system, Human Resources for Health (HRH) and Essential Medicines and Medical Supplies (EMMS) management, we analysed the early implementation experiences of this major governance reform at county level. We employed a qualitative case study design, focusing on Kilifi County, and adapted the decision space framework developed by Bossert et al., to guide our inquiry and analysis. Data were collected through document reviews, key informant interviews, and participant and non-participant observations between December 2012 and December 2014. As with other county level functions, HRH and EMMS management functions were rapidly transferred to counties before appropriate county-level structures and adequate capacity to undertake these functions were in place. For HRH, this led to major disruptions in staff salary payments, political interference with HRH management functions and confusion over HRH management roles. There was also lack of clarity over specific roles and responsibilities at county and national government, and of key players at each level. Subsequently health worker strikes and mass resignations were witnessed. With EMMS, significant delays in procurement led to long stock-outs of essential drugs in health facilities. However, when the county finally managed to procure drugs, health facilities reported a better order fill-rate compared to the period prior to devolution. The devolved government system in Kenya has significantly increased county level decision-space for HRH and EMMS management

  7. Green Schools on Ordinary Budgets (United States)

    Hanson, Mark E.


    Some in the green building industry have spoken for some time now of green buildings not needing to cost more. Jason McLennan in his 2004 book "The Philosophy of Sustainable Design" discusses not falling into the "green is always more" syndrome. He goes on to explain the concept of tunneling through the cost barrier. A 2007…

  8. Kuula. Kuu artist The Verve. Kuu plaat / Mart Juur

    Index Scriptorium Estoniae

    Juur, Mart, 1964-


    Inglise ansamblist. Heliplaatidest: Rulers of the Deep "Ready to Go Overground", Roni Size Reprazent "New Forms", Jason Mraz "We sing, We dance, We Steal Things", Morten Harket "Letter From Egypt", Primal Scream "Beautiful Future", Bill Frisell "History, Mystery", We Are Scientists "Brain Thurst Mastery"

  9. Never a dull day as a vet working in public health. (United States)

    Aldiss, Jason


    Jason Aldiss entered vet school in New Zealand knowing that he didn't want to go into general practice. Despite that, after qualifying he did spend two years in large animal practice. Having taken a keen interest in the role vets can play in society, he came to the UK to become an Official Veterinarian. British Veterinary Association.

  10. Manhunting: Counter-Network Organization for Irregular Warfare (United States)


    ington Post, 7 April 2008, cle/2008/04/06/AR2008040601841.html; accessed July 2009. Jason Sherman, “New...MACV-SOG MIA/KIA Chronological List,” b. 2001,; accessed July 2009. 129. Paola Evans, Kim Healey , Peter Kornbluh, Ramón Cruz

  11. Final Environmental Impact Statement for Proposed Barry M. Goldwater Range East Range Enhancements and Record of Decision for the Barry M. Goldwater Range East Range Enhancements, Final Environmental Impact Statement Dated November 26, 2010 (United States)


    Administration with 2 years experience. Rachel Healey Socioeconomics Hazardous Materials and Waste B.S. in Biology, M.B.A., with 5 years...Arizona. Neuzil, Anna, Jill Hjeilman, Jason Sperinck, Daniel Garcia, Helena Ruter, Bruce G. Phillips. 2009. Draft Report on Intensive Archaeological

  12. Cyber Workforce Retention (United States)


    Project Air Force. Santa Monica, CA: RAND Corporation, 2012. Healey , Jason . “Claiming the Lost Cyber Heritage.” Strategic Studies Quarterly 6, no. 3...We next look at specific options to reshape, grow, and retain a sustainable 1B4 cyber force for the future. Notes 1. Healey , “Lost Cyber Heritage

  13. Early Life Processes, Endocrine Mediators and Number of Susceptible Cells in Relation to Breast Cancer Risk (United States)


    Sweden, for overseeing the DNA isolation from the blood sam- ples; Heng Khai Koon and Ong Eng Hu Jason for genotyping; Lim Siew Lan and Irene Chen for...polymorphisms with sporadic breast cancer. Int J Cancer 2001, 95:271-275. 35. Dunning AM, Healey CS, Pharoah PD, Teare MD, Ponder BA, Eas- ton DF: A systematic

  14. Statistical Methods for Studying Genetic Variation in Populations (United States)


    using multilocus genetic data. Genetics, 160(3):1217–1229, 2002. 2.2, 3.1 Antonis C Antoniou, Amanda B Spurdle, Olga M Sinilnikova, Sue Healey , Karen A...Timmermann, Marius Tolzmann, Jason Affour- tit, Dana Ashworth, Said Attiya, Melissa Bachorski, Eli Buglione, Adam Burke, Amanda Caprio, Christopher Celone

  15. Does It Matter How the U.S. Army Organizes To Deal with Cyber Threats? (United States)


    University Press, 2012. Healey , Jason . A Fierce Domain: Conflict in Cyberspace, 1986 to 2012. Washington, DC: Cyber Conflict Studies Association, 2013...development and appropriations to create and support organizations tasked with providing national cyber security. John Healey of the Cyber Healey demonstrates the development of cyber security by discussing case histories of actual cyber attacks and the policy issues they

  16. Nonparametric Bayesian Context Learning for Buried Threat Detection (United States)


    up for years to come. I also want to three brave souls who entered the PhD program with me in 2007 - Kyle Bradbury, Jason Yu, and Phil Brown. If I...Geoscience and Remote Sensing, vol. 46, pp. 172–178, January 2008. [127] G. Healey and D. Slater, “Invariant recognition in hyperspectral images,” in IEEE

  17. Identification, Characterization and Clinical Development of the New Generation of Breast Cancer Susceptibility Alleles (United States)


    M, Seal S, Ghoussaini M, Hines S, Healey CS, Hughes D, Warren-Perry M, Tapper W, Eccles D, Evans DG, The Breast Cancer Susceptibility Collaboration...Jake Byrnes4, Sian Caesar21, Chris M. Clee2, Alison J. Coffey2, John M. C. Connell22, Jason D. Cooper5, Anna F. Dominiczak22, Kate Downes5, Hazel E

  18. Spectral Textile Detection in the VNIR/SWIR Band (United States)


    International Con- ference on, volume 2, 195–199 vol.2. Aug 1996. ISSN 1051-4651. 104 37. Guyon, Isabelle, Jason Weston, Stephen Barnhill, Vladimir Vapnik...Manufacturing Informatization (ICSEM), 2010 International Conference on, volume 1, 27–30. Nov 2010. 109 76. Thai, B. and G. Healey . “Invariant subpixel

  19. Sensors to Support the Soldier (United States)


    sponsorship of the Office of Naval Research. Paul Gido (Asst. Vice Chief of Naval Research, ONR) served as POC. The charge, which was proposed by JASON itself...23] F. E. Nathanson . Radar- Design Principles. McGraw-Hill, New York. 2nd edition, 1990. [24] ITU Radiocommnunication Assembly. Propagation data and

  20. Long-term sea level change in the Malaysian seas from multi-mission altimetry data

    NARCIS (Netherlands)

    Din, A.H.; Omar, K.M.; Naeije, M.C.; Ses, S.


    The long-term sea level change during 1993 to 2008 was investigated in the Malaysian seas from satellite altimetry data of the TOPEX, JASON-1, ERS-1, ERS-2 and ENVISAT missions. Sea level data retrieval and reduction were carried out using the radar altimeter database system (RADS). In RADS data

  1. Video - Real Rights: Decentralization and Women in South Asia ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Material from the videos are based on research projects lead by the Centre for Development Studies, ForestAction, Rural Support Programmes, Society for Promoting Participative Eco-System Management, and UNATI – Organization for Development Education. Photography and video are by Jason Taylor. Videos are in ...

  2. The Acceleration of Structural Microarchitectural Simulation via Scheduling (United States)


    by Jason Blome and Jonathan Cheng. Ram Rangan and Julia S. Chen contributed several valuable modules and models used in this dissertation. And various...Transactions on Computer-Aided Design, 5(4), October 1986. [4] T. E. Anderson, D. E. Culler , and D. A. Patterson. A case for networks of workstations

  3. Global Genomic Analysis of Prostate, Breast and Pancreatic Cancer (United States)


    Jul-Aug;2(4):459-70. 39. Kuestner RE, Taft DW, Haran A, Brandt CS, Brender T, Lum K, et al. Identification of the IL-17 receptor related molecule...Katherine E. Varley1, Jason Gertz1, Nick S. Davis1, Devin M. Absher1, James D. Brooks2, and Richard M. Myers1 1HudsonAlpha Institute for

  4. Response to Yiannis Miralis, "Manos Hadjidakis: The Story of an Anarchic Youth and a "Magnus Eroticus"" (United States)

    Helfer, Jason


    There are two issues that struck the author, Jason Helfer, as essential from his consideration of Miralis' paper and the ideas of Manos Hadjidakis: Eros as a pedagogical idea and learner interactions in the music classroom. These ideas developed from his interpretation of Miralis' paper, from his experiences in teacher training, and teaching in…

  5. Plaadid : Pop& rock. Etno. Klassika

    Index Scriptorium Estoniae


    Uutest heliplaatidest Radiohead "I Might Be Wrong", Spears, Britney "Britney", Mick Jagger "Goddess In The Doorway", DMX "The Great Depression", Alcazar "Casino", Ben & Jason "Ten Songs About You", Rachid Taha "Live", ABBA "The Definitive Collection", James Last "Plays ABBA Greatest Hits", Musica Fiata Köln/Roland Wison "Rosenmüller-Requiem"

  6. High-resolution residual geoid and gravity anomaly data of the northern Indian Ocean - An input to geological understanding

    Digital Repository Service at National Institute of Oceanography (India)

    Sreejith, K.M.; Rajesh, S.; Majumdar, T.J.; Rao, G.S.; Radhakrishna, M.; Krishna, K.S.; Rajawat, A

    ') geoid anomaly map of the northern Indian Ocean generated from the altimeter data obtained from Geodetic Missions of GEOSAT and ERS-1 along with ERS-2, TOPEX/POSIDEON and JASON satellites is presented. The geoid map of the Indian Ocean is dominated by a...

  7. FY08 DRMRP Clinical Trial: Strengthening Pathways to PTSD Recovery Using Systems-Level Intervention (United States)


    gators: Fort Bliss—Melissa Molina, MD, Stanley Harmon, RN, MSN, FNP ; Fort Bragg—Lillie Walker, MPAS, PA-C, Andrew Fletcher, MD, LTC, MC, Thurman Saunders...MSN, FNP -C, MAJ, AN; Fort Campbell—Lisa Ford, LTC, AN, FNP -BC, Vlatka Plymale, DO, CPT, MC, Jason Dailey, MD, MAJ, MC; Fort Carson—Nicholas Piantanida

  8. 77 FR 6112 - Notice of Final National Pollutant Discharge Elimination System (NPDES) General Permit for... (United States)


    ... the permitting authority (See Part VII Definitions, ``CAFOs'') and that are subject to 40 CFR part 412... feeding operations listed above which meet the definition of a CAFO and discharge pollutants to waters of... Enterprises (Jason Hitch); Hitch Enterprises (Patricia Burt); JBS Five Rivers Cattle Feeding LLC, Oklahoma...

  9. Smoking in the United States Air Force: Trends, Most Prevalent Diseases and their Association with Cost (United States)


    Talcott, Harry Lando, and Risa J. Stein. “Smoking prevalence and risk factors for smoking in a population of United States Air Force basic trainees...Stein, Risa J., Sara A. Pyle, C. Keith Haddock, W.S. Carlos Poston, Robert Bray, and Jason Williams, “ Reported stress and its relationship to tobacco

  10. Mirror, Mirror on the Wall: Email as an Object of Practitioner Inquiry (United States)

    Maxwell, Sally V.


    As new communication technologies enter the classroom, teachers must attend to how digital platforms impact the interpersonal practices of teaching and learning. In this article, I study email exchanges with three of my students--Jorge, Adriana, and Jason--over the course of one year in an 11th-grade English class at River High School, a…

  11. There Still Be Dragons: Racial Disparity in School Funding Is No Myth (United States)

    Miller, Raegen; Epstein, Diana


    It's hard to debunk a myth that's not a myth, but Jason Richwine of the Heritage Foundation has given it a try in his recent backgrounder, "The Myth of Racial Disparities in Public School Financing." The report suggests that public education spending is broadly similar across racial and ethnic groups, and it has found a predictably receptive…

  12. 2013 Schroth faces of the future symposium to highlight early career professionals in Mycology (United States)

    The 2013 Schroth Faces of the Future symposium was created to recognize early career professionals (those within 10 years of graduation) who represent the future in their field via innovative research. For this year, future faces in mycology research were recognized. Drs. Jason Slot, Erica Goss, Jam...

  13. Cross-Cultural Competence: Leader Requirements for Intercultural Effectiveness in the Human Domain (United States)


    application, cultural anthropology , sociology, military doctrine, and defense strategy. In addition, while doing so, they managed to demonstrate great...and cultural anthropology experts, among others. Another area for further research is to determine how to resolve high ethnocentrism (or...Michael Beemer, Jason M. Brunner, and Brandon McGowen. 2009. The human dimension of advising: An analysis of interpersonal, linguistic , cultural, and

  14. Summary and Findings of the ARL Dynamic Failure Forum (United States)


    Amann JF, Balzar S, Barnes Jr PD, Crow ML, Cushing SB, Eddleman JC, et al. An 800-MeV proton radiography facility for dynamic experiments. Nuclear...Development and Engineering Center Lee Magness US Army Research Laboratory Jim McCauley US Army Research Laboratory Jason McDonald US Army Research

  15. Kaabeltelevisioon jõuab mobiiltelefonidesse / Margus Mihkels

    Index Scriptorium Estoniae

    Mihkels, Margus


    Kaabeltele- ja internetivõrguga ühendatav Slingbox suudab koju tellitud teleprogrammid interneti kaudu mis tahes mobiiltelefoni või pihuarvuti ekraanile tuua, kinnitab lahenduse välja töötanud firma Sling Media kaasasutaja Jason Krikorian

  16. Proceedings of the Edgewood Chemical Biological Center In-House Laboratory Independent Research and Surface Science Initiative Programs FY12 (United States)


    APPROVED FOR PUBLIC RELEASE "Designing Strongly Repellant Surfaces via Molecular Dynamics Simulations" (PI: Cabalo ). This study used atomistic simulations...from Metallic Nanoparticles and Nanostructured Surfaces Jason Guicheteau, Ashish Tripathi, Erik Emmons, Jerry Cabalo , Craig Knox, Brandon Scott...Surfaces via Molecular Dynamics Simulations Craig Knox, Jerry Cabalo , Stephanie Ihejirika, Gary Kilper 116 Vll APPROVED FOR PUBLIC RELEASE Vlll

  17. Direct Functionalization of Kevlar (registered trademark) with Copolymers Containing Sulfonyl Nitrene (United States)


    OF KEVLAR ® WITH COPOLYMERS CONTAINING SULFONYL NITRENES by Jeremy Yatvin* Shalli A. Sherman Shaun F. Filocamo and Jason Locklin...Journal Article 3. DATES COVERED (From - To) September 2013-January 2015 4. TITLE AND SUBTITLE DIRECT FUNCTIONALIZATION OF KEVLAR ® WITH COPOLYMERS...phenylene terephthalamide) ( Kevlar ®) fibers via thermal generation of an electrophilic nitrene, while preserving the mechanical properties of the

  18. Investigating Alternatives to Broad-Scale Pesticide Spraying for Control of Lyme Disease Risk (United States)

    More than 20,000 cases of Lyme disease are reported annually in the US. Here in the Northeast, the geographic range of the disease and infection rates continue to increase. Beginning this summer, scientists from EPA Region 1 (Robert Koethe, Bart Hoskins) and ORD (Jason Grear) w...

  19. Always Feed the Clowns and Other Tips for Building Better Partnerships between School Librarians and Providers of Educational Programs (United States)

    Edwards, Jason


    Jason Edwards travels to schools and libraries across the nation performing educational enrichment programs, such as his Monster Hunt Library Skills-Building Adventure Program, for librarians and students. In this article, he shares tips that he has gleaned that may help librarian/programmer partnerships function more smoothly. Three of the…

  20. 77 FR 44593 - Burlington Coat Factory Warehouse Corporation, Provisional Acceptance of a Settlement Agreement... (United States)


    ... Group LLC--Apple Bottom hooded jackets; Millennium Apparel Group Inc.--Disney Winnie the Pooh hooded...) days of service of the Commission's final Order accepting the Settlement Agreement. DATES: Any..., Inc.--Jewel hooded sweatshirts; Jason Evans Associates, LLC--Bay Trading hooded sweatshirts and...

  1. Acquiring Information from Wider Scope to Improve Event Extraction (United States)


    Baldridge 2004; Becker and Osborne 2005; Reichart and Rappoport 2007), and word sense disambiguation (Chen et al. 2006;   71   Zhu and Hovy 2007...Jason Baldridge . 2004. Ensemble-based active learning for parse selection. In Proceedings of Human Language Technology Conference- the North

  2. The Courage to Critique Policies and Practices from within: Youth Participatory Action Research as Critical Policy Analysis. A Response to ""Buscando la Libertad": Latino Youths in Search of Freedom in School" (United States)

    Welton, Anjale


    This response to ""Buscando la Libertad": Latino Youths in Search of Freedom in School" by Jason G. Irizarry demonstrates how youth participatory action research (YPAR) as an instrument of subverting oppressive school policies and structures is a form of critical policy analysis (CPA). As an evolving method, CPA acknowledges the absent voices in…

  3. New Innovations and Best Practices under the Workforce Investment Act. Hearing before the U.S. House of Representatives, Subcommittee on Higher Education, Lifelong Learning, and Competitiveness, Committee on Education and Labor (February 12, 2009) (United States)

    US House of Representatives, 2009


    This Subcommittee on Higher Education, Lifelong Learning, and Competitiveness hearing on "New Innovations and Best Practices under the Work-force Investment Act," better known as WIA, is about the reauthorization of the Workforce Investment Act. Members testifying before the Committee were the Honorable Jason Altmire, a Representative in…

  4. Research report 1975/1976

    International Nuclear Information System (INIS)

    Rogers, M.D.; Lakey, J.R.A.


    The activities of the Royal Naval College, Greenwich, Department of Nuclear Science and Technology, during 1975/1976 are reported under sections entitled: general; radiation physics and technology; environmental studies; chemistry and materials; engineering research; computing; the Jason Research and Training Reactor; personal research interest. (U.K.)


    National Stormwater Calculator: Low Impact Development Stormwater Control Cost Estimation Programming & Future EnhancementsJason Berner1; Michael Tryby1; Scott Struck2, Dan Pankani2, Marion Deerhake3, Michelle Simon11. USEPA2. GeoSyntec, Inc.3. RTI, Inc.The National Stormwater Ca...

  6. Assessing the Net Effects of Sanctions on the Proliferation of Weapons of Mass Destruction (United States)


    Gary Clyde Hufbauer, Jeffrey J. Schott, Kimberly Ann Elliot, and Barbara Oegg , Economic Sanctions Reconsidered: History and Current Policy, Third...Schott, Kimberly Ann Elliot, and Barbara Oegg , Economic Sanctions Reconsidered: History and Current Policy, Third edition, (Washington D.C...Jason D. and Geoffrey D. Kiefer . Combating Proliferation: Strategic Intelligence and Security Policy. Baltimore: The Johns Hopkins University Press

  7. Using Market Segmentation to Develop a Large Section, Web-Enhanced Survey Course (United States)

    Cole, Jason; Robertson, Bruce


    Increasing enrollment and decreasing budgets have caused many public universities, such as San Fransisco State University (SFU), to offer mega-sections of courses to hundreds of students. Yet the needs of many students are at odds with the large enrollments, inflexible times, and inconvenient locations of these classes. Jason Cole and Bruce…

  8. 77 FR 545 - Qualification of Drivers; Exemption Applications; Vision (United States)


    ... K. Fultz (KY) John E. Kimmet, Jr. (WA) Robert S. Larrance (TN) Robert C. Leathers (MO) Jason L. Light (WA) Donald R. McCracken (OR) Kenneth R. Murphy (WA) Michael J. Richard (LA) Robert E. Sanders (LA) Robert A. Sherry (PA) Stephen G. Sniffin (CT) John R. Snyder (WA) The exemptions are extended subject to...

  9. Vliv oceánských slapů na nízké oběžné dráhy družic Země

    Czech Academy of Sciences Publication Activity Database

    Štěpánek, P.; Bezděk, Aleš


    Roč. 59, č. 5 (2013), s. 89-99 ISSN 0016-7096 Grant - others:GA(CZ) GCP209/11/J082 Institutional support: RVO:67985815 Keywords : SPOT-5 * Jason-2 * perturbation forces Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  10. 78 FR 55064 - Solicitation for Members of the NOAA Science Advisory Board (SAB) Gulf Coast Ecosystem... (United States)


    .../index.html . Dated: September 3, 2013. Jason Donaldson, Chief Financial Officer/Chief Administrative Officer, Office of Oceanic and Atmospheric Research, National Oceanic and Atmospheric Administration... Act Science Program's roles within the context of NOAA's ocean missions and policies. They should be...

  11. 77 FR 74175 - Solicitation of Review Editors for the Draft Report of the National Climate Assessment and... (United States)


    ... Climate Change Science; The NCA Long-Term Process. Dated: December 6, 2012. Jason Donaldson, Chief Financial Officer/Chief Administrative Officer, Office of Oceanic and Atmospheric Research, National Oceanic... Assessment 2013 Draft Report. Review Editor Role In the NCA Process: One Review Editor for each NCA 2013...

  12. Prognosis of tetanus patients in the intensive care unit of Provincial ...

    African Journals Online (AJOL)

    Tetanus is still a public health problem in developing countries including the Democratic Republic of Congo. The objective of this study was to determine the prognosis of patients with tetanus admitted in the Intensive Care Unit (ICU) of Provincial Hospital Jason Sendwe,Lubumbashi, DR Congo. This is a descriptive study ...

  13. Technology: The Good, the Bad and the Ugly. FACTC Focus, 2007 (United States)

    Doerr, Mark, Ed.


    "FACTC Focus" is a publication of Faculty Association of Community and Technical Colleges (FACTC) with the purpose of presenting diverse views on faculty issues. Included in this issue are: (1) Teaching Underwater (Jill Stukenberg); (2) The Ready Made Audience (Jason Nix); (3) Success or Insanity (J. Salas); (4) U Tube and Flickr…

  14. Hacking Say and Reviving ELIZA: Lessons from Virtual Environments (United States)

    Mazar, Rochelle; Nolan, Jason


    As text-based predecessors to Second Life, MOOs can offer educators important insights on managing virtual communities to create rich, meaningful learning experiences. Rochelle Mazar and Jason Nolan outline two instructional experiments in MOOs that have implications for current educational practice in Second Life. One involves modifying and…

  15. Adolescent Nonmedical Prescription Drug Use (United States)

    Ford, Jason A.; Watkins, William C.


    For many adolescents today, the most common form of substance use is nonmedical prescription drug use. Fittingly, many researchers, policy makers, and people who work with youth are concerned about the serious problems associated with nonmedical prescription drug use (NMPDU). In this article, authors Jason Ford and William Watkins provide an…

  16. Do Public School Teachers "Really" Receive Lavish Benefits? Richwine and Biggs' Recent Report Doesn't Make the Grade. EPI Issue Brief #324 (United States)

    Morrissey, Monique


    When most people think of the perks of teaching, an image that comes to mind is a shiny apple presented by a gap-toothed pupil. A recent paper by Jason Richwine of the Heritage Foundation and Andrew Biggs of the American Enterprise Institute claims that public school teachers enjoy lavish benefits that are more valuable than their base pay and…

  17. Using Collaboration to Understand Border Security and Cartels [video


    Jones, Jason


    Jason Jones, Captain (ret) Texas Department of Public Safety, is interviewed in this first episode of a series of Casual Conversations with CHDS Alumni and other subject matter experts in Homeland Security. This video focuses on the importance of collaboration among US organizations to understand cartels and border security.

  18. Organizing a Practice Session for Maximum Effectiveness (United States)

    DeGroot, Joanna


    According to Jason Paulk, director of choral activities at Eastern New Mexico University, progress is made during those in-between times and that progress magnifies with efficient time spent alone. Paulk is a firm believer in the importance of singers organizing their practice sessions, and he details some effective organization methods, including…

  19. Jänkid vallutasid Rooma / Triin Teramäe

    Index Scriptorium Estoniae

    Teramäe, Triin


    Teiselt Rooma filmifestivalilt, kus Marcus Aureliuse parima filmi auhinna sai USA "Juno" (režissöör Jason Reitman). Huvitavaid filme : Francis Ford Coppola "Noorus ilma nooruseta" ("Jouth without Youth"), Robert Redfordi "Kes liigutavad ettureid" ("Lions for Lambs"), Sean Penni "Metsikusse loodusesse" ("Into the Wild"), dokfilm Sophie Lorenist "Sophia: eile, täna, homme" jt. Lisatud auhindade nimekiri

  20. Kepler Planet-Detection Mission: Introduction and First Results (United States)


    20 Derek Buzasi,22 David Charbonneau,10 Laurance Doyle,5 Jonathan Fortney,24 Eric B. Ford,13 Matthew J. Holman,10 Sara Seager ,25 Jason H. Steffen,26...2008), pp. 405–418. 35. I. Baraffe, G. Chabrier, T. Barman, Astron. Astrophys. 482, 315 (2008). 36. E. R. Adams, S. Seager , L. Elkins-Tanton, Astrophys

  1. Carbon nanotube reinforced polymer composites–A state of the art

    Indian Academy of Sciences (India)


    Shaffer M S P, Fan X and Windle A H 1998 Carbon 36 1603. Siochia Emilie J, Working Dennis C, Park Cheol, Lilleheia. Peter T, Rouse Jason H, Topping Crystal C, Bhattacharyya. A R and Kumar Satish 2004 Composites B35 439. Song Young Seok and Youn Jae Ryoun 2004 e-Polymers No. 080 1. Treacy M M J, Ebbesen ...

  2. 75 FR 37707 - Administrative Process for Seizures and Forfeitures Under the Immigration and Nationality Act and... (United States)


    ... and Nationality Act and Other Authorities AGENCY: Office of the Secretary, DHS. ACTION: Final rule... consolidated the asset seizure and forfeiture procedures for customs and immigration purposes. The interim... Ressin, Penalties Branch, U.S. Customs and Border Protection (202) 325-0050. For ICE: Jason J. Johnsen...

  3. 2012 Year-End Report on Neurotechnologies for In-Vehicle Applications (United States)


    Chris Stachowiak , and Kaleb McDowell ARL-SR-267 June 2013 Approved for public release...J. Lance, W. David Hairston, Greg Apker, Keith W. Whitaker, Scott E. Kerick, Chris Stachowiak , and Kaleb McDowell Human Research and Engineering...Kerick, Jason Metcalfe, * Christopher Manteuffel, * Matthew Jaswa, * Jonroy Canady, * Victor Paul, † Jennifer Ammori, † Chris Stachowiak , and

  4. Acquisition of Thermal Gravimetric Analyzer and Differential Scanning Calorimeter for Enhancing Science and Engineering Education and DOD-relevant research at Miami University (United States)


    of novel papers TGA Student project; synthesis. Moringa Seed Extract for novel coagulant for water treatment Biopolymer...Reason for Use Dr. Justin Saul Keratin hydro_gel for novel adsorbent DSC Senior Design; synthesis. Education Dr. Jason Moringa Seed Extract for novel

  5. Global gravity field from recent satellites (DTU15) - Arctic improvements

    DEFF Research Database (Denmark)

    Andersen, O. B.; Knudsen, P.; Kenyon, S.


    Global marine gravity field modelling using satellite altimetry is currently undergoing huge improvement with the completion of the Jason-1 end-of-life geodetic mission, but particularly with the continuing Cryosat-2 mission. These new satellites provide three times as many geodetic mission altim...

  6. Combining Envisat type and CryoSat-2 altimetry to inform hydrodynamic models

    DEFF Research Database (Denmark)

    Schneider, Raphael; Nygaard Godiksen, Peter; Villadsen, Heidi


    . Satellite radar altimeters provide water level measurements of inland water bodies. So far, many studies making use of satellite altimeters have been based on data from repeat-orbit missions such as Envisat, ERS or Jason or on synthetic wide-swath altimetry data as expected from the SWOT mission. This work...

  7. Komedija "Dzhuno" stala triumfatorom nezavissimogo "Oskara"

    Index Scriptorium Estoniae


    Santa Monicas USAs anti 23. veebruaril üle sõltumatu kino aastaauhinnad Spirit Awards. Parimaks filmiks tunnistati Jason Reitmani "Juno", parim stsenaarium oli samale filmile Diablo Cody sulest, parim naisnäitleja Ellen Page samast filmist, parim režissöör filmi "Skafander ja liblikas" looja Julian Schnabel

  8. Fundamental surprise in the application of airpower (United States)


    their home countries, in which case further publication or sale of copyrighted images is not permissible. iii Abstract Fundamental Surprise in...Fundamental Surprise in the Application of Airpower A Monograph by Lt Col Jason A. Mascetta United States Air Force School of Advanced...Director, School of Advanced Military Studies James C. Markert, COL Accepted this 25th day of May 2017 by

  9. 26TH International Conference on Soils, Sediment, Water and Energy (United States)


    Development of phytosensors for monitoring environmental Arsenic Blake Joyce, Jason Abercrombie, and C. Neal Stewart, Jr., The University of Tennessee...GeoScience, Golden, CO; Scott D. Andrews, Essential Management Solutions (EMS), Evergreen, CO; Sara Handy, ARCADIS, Lakewood, CO Soils/Sediments

  10. Djavol kurit Marlboro. Prekrasnaja habalka. Iosseliani uhhodit na pensiju / Stass Tõrkin

    Index Scriptorium Estoniae

    Tõrkin, Stass


    Mängufilm "Thank You for Smoking" : režissöör Jason Reitman : Ameerika Ühendriigid 2005, Woody Alleni mängufilm "Sensatsioon" ("Scoop") : Ameerika Ühendriigid 2006 ja Otar Ioseliani "Sügisaiad" ("Gardens in Autumn") : Prantsusmaa 2006

  11. The Thermal Stabilization of Vaccines Against Agents of Bioterrorism (United States)


    Stability of Adenovirus Type 2 as a Function of pH Jason Rexroad’, Talia Martin1, David McNeilly, Simon Godwin2, and C. Russell Middaugh’* ’Department of...1507-1512. 19. Huyghe BG, Liu X, Sutjipto S, Sugarman BJ, Horn MT, Shepard HM, Scandella CJ, Shabram P 1995. Purification of a type 5 recombinant

  12. Prima Vistale tuleb tuntud kirjanikke mitmest Euroopa riigist / Kaarel Kressa

    Index Scriptorium Estoniae

    Kressa, Kaarel, 1983-


    Prima Vista kirjandusfestivali külalisi: Leonie Swann, Attila Bartis, Dmitri Bõkov, Zinaida Lindén, Mihhail Šiškin, Fay Weldon, Jason Goodwin, Rosa Maria Rodríguez Magda, Inga Gaile, Juris Kronbergs, Guntars Godinš, Liana Langa

  13. Improved Multispectral Skin Detection and its Application to Search Space Reduction for Dismount Detection Based on Histograms of Oriented Gradients (United States)


    Conference Series, volume 6699 of Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series. August 2007. 12. Brand, Jason and John S. Mason ...and Michael M. Wick. “Biochemistry and Physiology of Melanin Pigmentation”. Lowell A. Goldsmith (editor), Biochemistry and physiology of the skin

  14. Design of a Monocular Multi-Spectral Skin Detection, Melanin Estimation, and False-Alarm Suppression System (United States)


    Bibliography 1. Brand, Jason and John S. Mason . “A comparative assessment of three approaches to pixel-level human skin-detection”. Proceedings of 15th...Eurographics, (3). 19. Lowel -Light Manufacturing. “ Lowel Pro-light Instructions”, 2007. 20. Marschner, Stephen R., Stephen H. Westin, Eric P. Lafortune

  15. DEVELOP students attend conference (United States)


    Last month, Madeline Brozen and Jason Jones of the DEVELOP Program at John C. Stennis Space Center joined members from the program's national office at Langley Research Center to attend the Southern Growth Policies Board annual conference in Biloxi. Pictured are (l to r): Karen Allsbrook, Jonathan Gleason, Gov. Haley Barbour, Madeline Brozen, Lindsay Rogers and Tracey Silcox.

  16. Prior processes and their applications nonparametric Bayesian estimation

    CERN Document Server

    Phadia, Eswar G


    This book presents a systematic and comprehensive treatment of various prior processes that have been developed over the past four decades for dealing with Bayesian approach to solving selected nonparametric inference problems. This revised edition has been substantially expanded to reflect the current interest in this area. After an overview of different prior processes, it examines the now pre-eminent Dirichlet process and its variants including hierarchical processes, then addresses new processes such as dependent Dirichlet, local Dirichlet, time-varying and spatial processes, all of which exploit the countable mixture representation of the Dirichlet process. It subsequently discusses various neutral to right type processes, including gamma and extended gamma, beta and beta-Stacy processes, and then describes the Chinese Restaurant, Indian Buffet and infinite gamma-Poisson processes, which prove to be very useful in areas such as machine learning, information retrieval and featural modeling. Tailfree and P...

  17. Alcohol advertising and youth. (United States)

    Martin, Susan E; Snyder, Leslie B; Hamilton, Mark; Fleming-Milici, Fran; Slater, Michael D; Stacy, Alan; Chen, Meng-Jinn; Grube, Joel W


    This article presents the proceedings of a symposium at the 2001 Research Society on Alcoholism meeting in Montreal, Canada. The symposium was organized and chaired by Joel W. Grube. The presentations and presenters were (1) Introduction and background, by Susan E. Martin; (2) The effect of alcohol ads on youth 15-26 years old, by Leslie Snyder, Mark Hamilton, Fran Fleming-Milici, and Michael D. Slater; (3) A comparison of exposure to alcohol advertising and drinking behavior in elementary versus middle school children, by Phyllis L. Ellickson and Rebecca L. Collins; (4) USC health and advertising project: assessment study on alcohol advertisement memory and exposure, by Alan Stacy; and (5) TV beer and soft drink advertising: what young people like and what effects? by Meng-Jinn Chen and Joel W. Grube.

  18. Emirates Mars Mission Planetary Protection Plan (United States)

    Awadhi, Mohsen Al


    The United Arab Emirates is planning to launch a spacecraft to Mars in 2020 as part of the Emirates Mars Mission (EMM). The EMM spacecraft, Amal, will arrive in early 2021 and enter orbit about Mars. Through a sequence of subsequent maneuvers, the spacecraft will enter a large science orbit and remain there throughout the primary mission. This paper describes the planetary protection plan for the EMM mission. The EMM science orbit, where Amal will conduct the majority of its operations, is very large compared to other Mars orbiters. The nominal orbit has a periapse altitude of 20,000 km, an apoapse altitude of 43,000 km, and an inclination of 25 degrees. From this vantage point, Amal will conduct a series of atmospheric investigations. Since Amal's orbit is very large, the planetary protection plan is to demonstrate a very low probability that the spacecraft will ever encounter Mars' surface or lower atmosphere during the mission. The EMM team has prepared methods to demonstrate that (1) the launch vehicle targets support a 0.01% probability of impacting Mars, or less, within 50 years; (2) the spacecraft has a 1% probability or less of impacting Mars during 20 years; and (3) the spacecraft has a 5% probability or less of impacting Mars during 50 years. The EMM mission design resembles the mission design of many previous missions, differing only in the specific parameters and final destination. The following sequence describes the mission: 1.The mission will launch in July, 2020. The launch includes a brief parking orbit and a direct injection to the interplanetary cruise. The launch targets are specified by the hyperbolic departure's energy C3, and the hyperbolic departure's direction in space, captured by the right ascension and declination of the launch asymptote, RLA and DLA, respectively. The targets of the launch vehicle are biased away from Mars such that there is a 0.01% probability or less that the launch vehicle arrives onto a trajectory that impacts Mars

  19. Scientific Payload Of The Emirates Mars Mission: Emirates Mars Infrared Spectrometer (Emirs) Overview. (United States)

    Altunaiji, E. S.; Edwards, C. S.; Christensen, P. R.; Smith, M. D.; Badri, K. M., Sr.


    The Emirates Mars Mission (EMM) will launch in 2020 to explore the dynamics in the atmosphere of Mars on a global scale. EMM has three scientific instruments to an improved understanding of circulation and weather in the Martian lower and middle atmosphere. Two of the EMM's instruments, which are the Emirates eXploration Imager (EXI) and Emirates Mars Infrared Spectrometer (EMIRS) will focus on the lower atmosphere observing dust, ice clouds, water vapor and ozone. On the other hand, the third instrument Emirates Mars Ultraviolet Spectrometer (EMUS) will focus on both the thermosphere of the planet and its exosphere. The EMIRS instrument, shown in Figure 1, is an interferometric thermal infrared spectrometer that is jointly developed by Arizona State University (ASU) and Mohammed Bin Rashid Space Centre (MBRSC). It builds on a long heritage of thermal infrared spectrometers designed, built, and managed, by ASU's Mars Space Flight Facility, including the Thermal Emission Spectrometer (TES), Miniature Thermal Emission Spectrometer (Mini-TES), and the OSIRIS-REx Thermal Emission Spectrometer (OTES). EMIRS operates in the 6-40+ µm range with 5 cm-1 spectral sampling, enabled by a Chemical Vapor-Deposited (CVD) diamond beamsplitter and state of the art electronics. This instrument utilizes a 3×3 detector array and a scan mirror to make high-precision infrared radiance measurements over most of a Martian hemisphere. The EMIRS instrument is optimized to capture the integrated, lower-middle atmosphere dynamics over a Martian hemisphere and will capture 60 global images per week ( 20 images per orbit) at a resolution of 100-300 km/pixel. After processing through an atmospheric retrieval algorithm, EMIRS will determine the vertical temperature profiles to 50km altitude and measure the column integrated global distribution and abundances of key atmospheric parameters (e.g. dust, water ice (clouds) and water vapor) over the Martian day, seasons and year.

  20. Emirates Mars Infrared Spectrometer (EMIRS) Overview from the Emirates Mars Mission (United States)

    Altunaiji, Eman; Edwards, Christopher; Smith, Michael; Christensen, Philip; AlMheiri, Suhail; Reed, Heather


    Emirates Mars Infrared Spectrometer (EMIRS) instrument is one of three scientific instruments aboard the Emirate Mars Mission (EMM), with the name of "Hope". EMM is United Arab Emirates' (UAE) mission to be launched in 2020, with the aim of exploring the dynamics of the atmosphere of Mars on a global scale with sampling on a diurnal and sub-seasonal time-scales. EMM has three scientific instruments selected to provide an improved understanding of circulation and weather in the Martian lower atmosphere as well as the thermosphere and exosphere. The EMIRS instrument is an interferometric thermal infrared spectrometer that is jointly developed by Arizona State University (ASU) and Mohammed Bin Rashid Space Centre (MBRSC), Dubai, UAE. It builds on a long heritage of thermal infrared spectrometers designed, built, and managed, by ASU's Mars Space Flight Facility, including the Thermal Emission Spectrometer (TES), Miniature Thermal Emission Spectrometer (Mini-TES), and the OSIRIS-REx Thermal Emission Spectrometer (OTES). EMIRS operates in the 6-40+ μm range with 5 cm-1 spectral sampling, enabled by a Chemical Vapor-Deposited (CVD) diamond beam splitter and state of the art electronics. This instrument utilizes a 3×3 line array detector and a scan mirror to make high-precision infrared radiance measurements over most of the Martian hemisphere. The EMIRS instrument is optimized to capture the integrated, lower-middle atmosphere dynamics over a Martian hemisphere, using a scan-mirror to make 60 global images per week ( 20 images per orbit) at a resolution of 100-300 km/pixel while requiring no special spacecraft maneuvers.

  1. Importance of whole genome sequencing for the assessment of outbreaks in diagnostic laboratories: analysis of a case series of invasive Streptococcus pyogenes infections. (United States)

    Tagini, F; Aubert, B; Troillet, N; Pillonel, T; Praz, G; Crisinel, P A; Prod'hom, G; Asner, S; Greub, G


    Outbreaks of Streptococcus pyogenes hypervirulent clones are constant public health threats. In western Switzerland, an increase of severe cases of S. pyogenes invasive infections was observed between December 2015 and March 2016. Our aim was (i) to investigate these cases by the use of Whole Genome Sequencing (WGS) and (ii) to determine the specific virulome and resistome of each isolate in order to undertake adequate public health measures. Eleven Streptococcus pyogenes strains isolated from 11 patients with severe invasive infections between December 13, 2015 and March 12, 2016 were included in our study. Practically, emm-typing, MLST and WGS were used to investigate the relatedness between the isolates. The presence of virulence and antibiotic resistance genes as well as mutations in transcriptional regulators of virulence and in genes encoding for antibiotic targets were assessed. Three and two groups of isolates shared the same emm-type and ST type, respectively. Single Nucleotide Polymorphism (SNP) analysis revealed 14 to 32 SNPs between the strains of the same emm-type group, ruling out the possibility of a clonal outbreak. Mutations found in covS and rocA could partially explain an increased virulence. As these reassuring results were obtained in less than 10 days, no specific hospital hygiene and no dedicated public health measures had to be undertaken. WGS is a powerful technique to discriminate between closely related strains, excluding an outbreak in less than 10 days. Moreover, WGS provided extensive data on the virulome and resistome of all these strains.

  2. Virulence factors of Streptococcus pyogenes strains from women in peri-labor with invasive infections. (United States)

    Golińska, E; van der Linden, M; Więcek, G; Mikołajczyk, D; Machul, A; Samet, A; Piórkowska, A; Dorycka, M; Heczko, P B; Strus, M


    Invasive group A streptococcal (GAS) infections constitute an important epidemiological problem. Many cases occur in women during the postnatal period. The objective of this study was to evaluate the presence of the genes responsible for production of iron-chelating protein (perR) and superantigens (speA, speB, speC, speF, speG, speH, speI, speJ, speK, speL, speM, smeZ, and ssa) in S. pyogenes strains isolated from invasive infections in women after delivery. Furthermore, this study sought to verify whether S. pyogenes strains show special phenotypic and genotypic (sla, spy1325) characteristics that may play a decisive role in adherence to the genital tract epithelium. Moreover, the emm-types and antibiotic susceptibility were determined. We tested 30 invasive S. pyogenes strains isolated from postpartum invasive infection and 37 GAS control strains isolated from the genital tracts of asymptomatic multiparous women. The majority of the tested strains were shown to express two types of emm genes (1 and 28), though emm -12, -28, -75 and -89 were uniquely expressed in the group of strains isolated from invasive infections. A significantly higher prevalence of perR in the strains from puerperal fever was shown. Significant differences were also found between the two groups with respect to the incidence of the genes related to adherence; GAS strains originating from women with sepsis/puerperal fever showed presence of these genes less frequently than those of the control group. Although differences in frequencies of the gene coding for various superantigens were noted between the compared groups of GAS strains, they were not significant.

  3. EFEHR - the European Facilities for Earthquake Hazard and Risk: beyond the web-platform (United States)

    Danciu, Laurentiu; Wiemer, Stefan; Haslinger, Florian; Kastli, Philipp; Giardini, Domenico


    European Facilities for Earthquake Hazard and Risk (EEFEHR) represents the sustainable community resource for seismic hazard and risk in Europe. The EFEHR web platform is the main gateway to access data, models and tools as well as provide expertise relevant for assessment of seismic hazard and risk. The main services (databases and web-platform) are hosted at ETH Zurich and operated by the Swiss Seismological Service (Schweizerischer Erdbebendienst SED). EFEHR web-portal ( collects and displays (i) harmonized datasets necessary for hazard and risk modeling, e.g. seismic catalogues, fault compilations, site amplifications, vulnerabilities, inventories; (ii) extensive seismic hazard products, namely hazard curves, uniform hazard spectra and maps for national and regional assessments. (ii) standardized configuration files for re-computing the regional seismic hazard models; (iv) relevant documentation of harmonized datasets, models and web-services. Today, EFEHR distributes full output of the 2013 European Seismic Hazard Model, ESHM13, as developed within the SHARE project (; the latest results of the 2014 Earthquake Model of the Middle East (EMME14), derived within the EMME Project (; the 2001 Global Seismic Hazard Assessment Project (GSHAP) results and the 2015 updates of the Swiss Seismic Hazard. New datasets related to either seismic hazard or risk will be incorporated as they become available. We present the currents status of the EFEHR platform, with focus on the challenges, summaries of the up-to-date datasets, user experience and feedback, as well as the roadmap to future technological innovation beyond the web-platform development. We also show the new services foreseen to fully integrate with the seismological core services of European Plate Observing System (EPOS).

  4. Rock physics modeling of shallow marine sediments in the eastern continental margin of India

    Digital Repository Service at National Institute of Oceanography (India)

    Dewangan, P.; Sriram, G.; RamPrasad, T.

    for the intermediate porosity are calculated using lower Hashin-Shtrikman bound. The fluid-saturated moduli are estimated using Gassmann’s equation. The main limitation of this model is that it requires a lot of apriori information and is computationally involved... that are in a state of suspension, i.e. having no frame stiffness. The EMM model can be extended to estimate the hydrate and free gas concentration in marine sediments from porosity and velocity profiles (Helgerud, 1999). Lee (2006) showed that shear wave...

  5. 1026-IJBCS-Article-Bleu Michel

    African Journals Online (AJOL)


    soigner l'asthme, le vertige, les maux de tête et l'hystérie en Inde alors qu'au Brésil et sur l'île de la Réunion, elle est utilisée comme emménagogue et permet de traiter les maladies de la peau, les inflammations et l'hystérie (Dhawan et al., 2004). Passiflora foetida possède plusieurs propriétés pharmacologiques. Elle joue ...

  6. Proton exchange membrane fuel cells

    CERN Document Server

    Qi, Zhigang


    Preface Proton Exchange Membrane Fuel CellsFuel CellsTypes of Fuel CellsAdvantages of Fuel CellsProton Exchange Membrane Fuel CellsMembraneCatalystCatalyst LayerGas Diffusion MediumMicroporous LayerMembrane Electrode AssemblyPlateSingle CellStackSystemCell Voltage Monitoring Module (CVM)Fuel Supply Module (FSM)Air Supply Module (ASM)Exhaust Management Module (EMM)Heat Management Module (HMM)Water Management Module (WMM)Internal Power Supply Module (IPM)Power Conditioning Module (PCM)Communications Module (COM)Controls Module (CM)SummaryThermodynamics and KineticsTheoretical EfficiencyVoltagePo

  7. The diet of the fox (Vulpes vulpes in woodlands of Orobie Alps (Lombardy region, Northern Italy / Alimentazione della Volpe (Vulpes vulpes in aree boscate delle Alpi Orobie

    Directory of Open Access Journals (Sweden)

    Marco Cantini


    Full Text Available Abstract The diet of the fox was investigated by analysis of 273 scats, collected along standard trails from April to November 1987 and 1988. Food habits of foxes were described for three altitudinal ranges. Mammals, mainly Clethrionomys glareolus and Microtus multiplex, were the staple food (percentage of frequency 42.8%, followed by fruits and other vegetables (26.7% and 37.3% respectively. Birds, Invertebrates (mainly Insects and garbage were little eaten. The game species (ungulates, hares, pheasants occurred with a low frequency (8.4% in the diet. The trophic niche breadth varied little through the altitudinal ranges and the seasons. The trophic niche overlap between the fox and the genus Martes (190 scats of <em>M. martes and <em>M. foina were examined is relatively wide (O=0.868. Riassunto La dieta della Volpe (Vulpes vulpes in aree boscate delle Alpi Orobie (Val Lesina è stata indagata nel periodo aprile-novembre 1987 e 1988 mediante l'analisi di 273 feci, raccolte lungo percorsi-campione ricadenti in tre piani vegetazionali. I Mammiferi, in particolare Clethrionomys glareolus e Microtus multiplex, sono la componente principale della dieta (frequenza percentuale 42,8%. Rilevante è anche il consumo di frutti (soprattutto in estate e autunno e di altri vegetali (26,7% e 37,3% rispettivamente, mentre poco frequente è quello di Uccelli, Invertebrati e rifiuti. Complessivamente ridotta è l'azione predatoria della Volpe nei confronti delle specie di interesse venatorio (Ungulati, lepri, Galliformi. L'ampiezza della nicchia trofica mostra modeste variazioni stagionali e altitudinali. I1 grado di sovrapposizione tra la nicchia trofica della Volpe e quella del genere Martes, quest'ultima ricavata dall'analisi di 190 feci di Martora (<em>M. martes e Faina (<em>M. foina, è elevato (O=0,868. Tuttavia, poiché in condizioni di

  8. Integrating New Bellhop Functionality into the Environmental Modelling Manager (United States)


    analysis capability and towed-array receiver beam patterns. Résumé RDDC Atlantique a mis au point un système de prédiction acoustique de... acoustique Bellhop; lorsque les résultats sont prêts, elle les affiche dans le format graphique choisi par l’opérateur. L’EMM/EA était auparavant un...Atlantique a mis au point un système de prédiction acoustique de recherche, le Banc d’essai de systèmes (System Test Bed, STB), dans le but d’appuyer le

  9. Eremophila maculata-Isolation of a rare naturally-occurring lignan glycoside and the hepatoprotective activity of the leaf extract. (United States)

    Youssef, Fadia S; Ashour, Mohamed L; Sobeh, Mansour; El-Beshbishy, Hesham A; Singab, Abdel Nasser; Wink, Michael


    The Australian plant Eremophila maculata F. Muell (Scrophulariaceae) is cultivated worldwide as an ornamental plant. This study was designed to assess the antioxidant and hepatoprotective activities of a methanol extract from E. maculata leaves (EMM) both in vitro and in vivo (rats) experiments. Detailed phytochemical study was done on the extract followed by molecular docking experiments on TNF-α ascertain the efficacy of the isolated compounds. The antiproliferative activity was evaluated in the human cancer cell lines A-495, PC3 and HepG2 cells using the SRB method. The antioxidant activitywas evaluated in vitro using the DPPH• assay while the hepatoprotective properties were investigated by determining the amelioration of CCl 4 -induced cytotoxicity and oxidative stress in HepG2 cells. The activity was confirmed in vivo by studying tamoxifen-induced hepatotoxicity in rats. An in-depth phytochemical investigation of a methanol extract was performed using 1D and 2D NMR experiments. In silico molecular modeling studies of the isolated compounds on TNF-α (PDB ID 2AZ5) were carried out using Discovery Studio 2.5 software applying C-Docker protocol. The IC 50 values of EMM were >500µg/ml for both PC3 and HepG2 cells indicating its safety. Similar to the standard drug silymarin, EMM could restore AST, ALT values; replenish GSH level, SOD activity and TAC in vitro. The hepatoprotective activity was confirmed in vivo in which the extract (20mg/kg body weight) decreased ALT and AST levels by 45.23 and 45.79%, respectively as compared to the tamoxifen treated groups. Oxidative stress was reduced by lowering of thiobarbituric acid reactive substances by 28.57%. Additionally, hepatocyte inflammation was improved by reducing the pro-inflammatory mediator TNF-α by 54.29%. Phytochemical investigation resulted in the isolation of a rare naturally-occurring lignan glycoside, namely pinoresinol-4-O-[6″-O-(E)-feruloyl]-β-D-glucopyranoside for the first time from the

  10. Väikelasteraamatu konkursi eripreemia pälvis Koidu ajakirjanik

    Index Scriptorium Estoniae


    Väikelasteraamatu konkursil sai I-II koha vääriliseks Signe Ora "Mõista, mõista, Leenukene!" ning Juhani Püttsepa "Väikese hundi lood", III koha pälvis Annika Tontsu "Meesteraamat", ergutuspreemia sai Maret Põldre "Lugu hundipojast, kes tahtis endale jänest", eripreemia said Pirgit-Maarja Hallas ("Kass ja liblikas") ja Margit Õkva ("Õnne-Triin õpetab"). Ära märgiti veel Elina Sildre "Koerad" ning Kristiina Baumi "Tubli emme". Võistluse korraldas kultuuriministeerium koos kirjastusega Päike ja Pilv

  11. Assessment of the quality of HY-2A satellite sea surface height data (United States)

    Song, Qingtao; Gao, Xuemin; Wang, Zhaohui; Liu, Yuxin


    In August 2011, China successfully launched the Ocean II (HY-2A) satellite. HY-2A carries a dual-band radar altimeter with a calibrated microwave radiometer on the orbit. The main objective of HY-2A is to observe the elements of marine dynamic environment, including sea surface height. The evaluation of HY-2A satellite sea surface data quality is a necessary part of HY-2A satellite sea surface data application. We Used the HY-2A satellite 18th to 23th cycle data and the simultaneous Jason-2 data in orbit to analyze the deviation and evaluate of HY-2A satellite radar height data quality. The results show that the number of abnormal points in HY-2A satellite 18 to 23 cycles accounted for 12% of the total. HY-2A and Jason-2 sea level anomaly standard deviation of 7.0 cm that the accuracy of HY-2A reached the satisfaction index.

  12. Wind-driven Circulation and Freshwater Fluxes off Sri Lanka: 4D-Sampling with Autonomous Gliders (United States)


    off Sri Lanka : 4D-Sampling with Autonomous Gliders Craig M. Lee, Luc Rainville and Jason I. Gobat Applied Physics Laboratory, University of Washington...into the Arabian Sea south of Sri Lanka , as they transit along different pathways setup by the seasonally varying circulation. 1 DISTRIBUTION...the west coast of Sri Lanka into international waters, 400 km offshore (Fig. 2). These sections have been obtained in roughly every month of the year

  13. 24 Times


    Dee, Jason


    Jason Dee’s installation '24 Times' was part of a large-scale international exhibition: 'The Still Point of the Turning World: Between Film and Photography' at FOMU in Antwerp. The show ran for four months and included numerous highly significant current and historic international practitioners in the fields of photography and cinema. These included: Jeff Wall, Hiroshi Sugimoto, John Stezaker, Paul Graham, John Smith and David Claerbout. The exhibition was accompanied by a 216-page bi-lin...

  14. Independent Review of the Defense Logistics Agencys Roles and Missions (United States)


    Davidson Phyllisa Goldenberg Twila Gonzales Nancy Heimbaugh Redding Hobby BG Mark Johnson Milt Lewis Charles Lilli Jim McClaugherty RADM David Pimpo...Mark Harris Col Dan Hicks Dan Jennings Col Kevin Kachinski Charles Kaminski Bill Kenny Steven Kinskie David Kless David Koch Theresa Kyte...Willie Benz Conrad Bonner Mike Cervone Susan Cole Alivia Cowan Chris Cullen Jason Detko Cathy Dickens Gene Duncan Greg Etter COL Fuller (FMS

  15. The Role of Ethics in International Arms Transfers (United States)


    A Fierce Domain (Cyber Conflict Studies Association, 2013), 226. 10 Healey, ed., A Fierce Domain , 226...11 Grimmett, U.S. Arms Sales to Pakistan. 1. 12 Healey, ed., A Fierce Domain , 226. 13 Grimmett, U.S. Arms Sales to Pakistan, 2. 14 Williams, Bryan...Saudi Arabia, 45. 15 Jason Healey, ed., A Fierce Domain (Cyber Conflict Studies Association, 2013), 226. 16 Healey, A Fierce Domain , 215.



    East West Center, Honolulu, HI, no. 117. May 2015. Healy, Jason (ed). A Fierce Domain : Conflict in Cyberspace 1986 to 2012. (Washington, DC: Cyber...The Estonian Cyber Attacks,” A Fierce Domain : Conflict in Cyberspace, 1986 to 2012, (Washington DC: Cyber Conflict Studies Association, 2013), 186...188; Andreas Hagen, “The Russo-Georgian War 2008,” A Fierce Domain : Conflict in Cyberspace, 1986 to 2012, (Washington DC: Cyber Conflict Studies

  17. Orchestra of Change: Strategically Harmonizing National Character, Military Forces, and the Character of War (United States)


    89 Jason Healey , ed., A Fierce Domain : Conflict in Cyberspace, 1986 to 2012 (Washington, DC: Atlantic Council, 2013), 70–72. 90... A Fierce Domain : Conflict in Cyberspace, 1986 to 2012. Washington, DC: Atlantic Council, 2013. Hoffman, David E. The Dead Hand: The Untold Story...ORCHESTRA OF CHANGE: STRATEGICALLY HARMONIZING NATIONAL CHARACTER, MILITARY FORCES, AND THE CHARACTER OF WAR BY SCOTT GUNN A THESIS

  18. Is It Time for a US Cyber Force? (United States)

    2015-02-17 cyber-em-spectrum-changing-navy/ Healey , Jason. A Fierce Domain : Conflict in Cyberspace...and potential of the cyberspace domain ? Or is a separate force, independent of the other services and agencies, needed to project and protect vital...Defense establishment meet the demands and potential of the cyberspace domain ? Or is a separate force, independent of the other services and agencies

  19. COMBAT: A Prospective, Randomized Investigation of Plasma First Resuscitation for Traumatic Hemorrhage and Attenuation of Acute Coagulopathy of Trauma (United States)


    principal investigator, Jason L. Sperry, MD) and Virginia Commonwealth University (principal investigator, Bruce D. Spiess, MD). Notably, the COMBAT... Healey G: Reduced expres- sion of CD47 on stored red blood cells. Transfusion 2006; 46:1263 17 Veale MF, Healey G, Sparrow RL: Longer storage of red blood...2014.0305-13 [Epub ahead of print] 21 Sparrow RL, Sran A, Healey G, et al.: In vitro measures of membrane changes reveal differences between red blood

  20. Robust Multi-Agent Sensor Network Systems (United States)


    type of target tracking and navigation, target localisation is critical (Danchik, 1988; Healey et al., 1995; Poisel, 2005; Sabour et al., 2008; Tai...21–24, November–2 December. Healey , A.J., Pascoal, A.M. and Pereira, F.L. (1995) ‘Autonomous underwater vehicles for survey operations: theory and...method,” Statistical Science, vol. 5, no. 4, pp. 403–434, 1990. [33] A. D. Barbour, L. Holst, and S. Jason , Poisson Approxi- mation. Oxford University

  1. COMBAT - A Prospective, Randomized Investigation of Plasma First Resuscitation for Traumatic Hemorrhage and Attenuation of Acute Coagulopathy of Trauma (United States)


    principal investigator, Jason L. Sperry, MD) and Virginia Commonwealth University (principal investigator, Bruce D. Spiess, MD). Notably, the COMBAT... Healey G: Reduced expres- sion of CD47 on stored red blood cells. Transfusion 2006; 46:1263 17 Veale MF, Healey G, Sparrow RL: Longer storage of red blood...2014.0305-13 [Epub ahead of print] 21 Sparrow RL, Sran A, Healey G, et al.: In vitro measures of membrane changes reveal differences between red blood

  2. Nanobiotechnology in energy, environment and electronics methods and applications

    CERN Document Server

    Nicolini, Claudio


    Introduction: Present Challenges and Future Solutions via Nanotechnology for Electronics, Environment and Energy; Claudio NicoliniPart A: MethodsInfluence of Chromosome Translocation on Yeast Life Span: Implications for Long-Term Industrial Biofermentation; Jason Sims, Dmitri Nikitin, and Carlo V. BruschiPulsed Power Nanotechnologies for Disintegration and Breaking Up of Refractory Precious Metals Ores; Valentin A. Chanturiya and Igor Zh. BuninModeling of Software Sensors in Bioprocess; Luca Belmonte and Claudio NicoliniN

  3. Exploiting the genome

    Energy Technology Data Exchange (ETDEWEB)

    Block, S. [The MITRE Corporation, McLean, VA (US). JASON Program Office; Cornwall, J. [The MITRE Corporation, McLean, VA (US). JASON Program Office; Dyson, F. [The MITRE Corporation, McLean, VA (US). JASON Program Office; Koonin, S. [The MITRE Corporation, McLean, VA (US). JASON Program Office; Lewis, N. [The MITRE Corporation, McLean, VA (US). JASON Program Office; Schwitters, R. [The MITRE Corporation, McLean, VA (US). JASON Program Office


    In 1997, JASON conducted a DOE-sponsored study of the human genome project with special emphasis on the areas of technology, quality assurance and quality control, and informatics. The present study has two aims: first, to update the 1997 Report in light of recent developments in genome sequencing technology, and second, to consider possible roles for the DOE in the ''post-genomic" era, following acquisition of the complete human genome sequence.

  4. Al-Qaeda Core: A Case Study (United States)


    Quotes Blog , February 27, 2004, osama-bin.html, accessed February 21, 2017. blogs /clausewitz/2012/05/reading-abbottabad- papers. 46 Jason Burke, The New Threat: The Past, Present, and Future of Islamic...of Osama Bin Laden Statements.” Bin Laden Quotes Blog , February 27, 2004, accessed February 21, 2017.

  5. Worldwide C-17 Availability to Support 82nd Airborne Operations from Fort Bragg/Pope Field (United States)


    and LTC Jason W. Condrey of Army Forces Command for their support and input throughout the project. We must also thank Army Forces Command for its...Improvement Program kt knots LIMS -EV Logistics, Installations, Mission Support-Enterprise View nm nautical miles PMC partially mission capable USAF...Mission Support-Enterprise View ( LIMS -EV) that give the location and status of the C-17 fleet. Chapter 4 analyzes the model output focused on a heatmap of

  6. Molecular Dynamics and Morphology of High Performance Elastomers and Fibers by Solid State NMR (United States)


    nuclear magnetic resonance (ssNMR) spectroscopy to investigate the chemical structure and physical state of the residual phosphorous in PBO fiber...ssNMR) spectroscopy to investigate the chemical structure and physical state of the residual phosphorous in PBO fiber, which has been long suspected to...Jason Cain, Jian H. Yu, David Veysset, Keith A. Nelson . Probing the Influence of Molecular Dynamics of Matrix Elastomers on Ballistic Impact Back-face

  7. Determining the Optimal Inventory Management Policy for Naval Medical Center San Diego’s Pharmacy (United States)


    budget. It is a very good tool for those hospitals that have a restrictive formulary. There is also the option to combine these to analyses into the...evaluating the inventory of a pharmacy and should be used in conjunction with a tool that takes non- monetary factors into consideration. The VEN analysis...OPTIMAL INVENTORY MANAGEMENT POLICY FOR NAVAL MEDICAL CENTER SAN DIEGO’S PHARMACY by Jason S. Galka December 2016 Thesis Advisor: Eddine

  8. Energizing the Enterprise: An Incentive-Based Approach to Homeland Security (United States)


    happen, but so far, they have not. To assume that Americans live in a vacuum—that they will only understand what we spoon - feed them—is naive...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release; distribution is unlimited ENERGIZING THE...S) Jason B. Porter 5. FUNDING NUMBERS 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School Monterey, CA 93943-5000 8

  9. Reactor physics in support of the naval nuclear propulsion programme

    International Nuclear Information System (INIS)

    Lisley, P.G.; Beeley, P.A.


    Reactor physics is a core component of all courses but in particular two postgraduate courses taught at the department in support of the naval nuclear propulsion programme. All of the courses include the following elements: lectures and problem solving exercises, laboratory work, experiments on the Jason zero power Argonaut reactor, demonstration of PWR behavior on a digital computer simulator and project work. This paper will highlight the emphasis on reactor physics in all elements of the education and training programme. (authors). 9 refs

  10. Converting a Manned LCU into an Unmanned Surface Vehicle (USV): An Open Systems Architecture (OSA) Case Study (United States)


    Ray Marcantonio, and John Vasilakos. 2010. “Standard Processes for the Design of Modular Spaces.” Engineering the Total Ship Symposium Proceedings...Savitz, Scott. Irv Blickstein, Peter Buryk, Robert W. Button, Paul DeLuca, James Dryden , Jason Mastbaum, Jan Osburg, Philip Padilla, Amy Potter, Carter C...Price, Lloyd Thrall, Susan K. Woodward, Roland J. Yardley, and John M. Yurchak. Accessed May 1, 2013.

  11. Accounting for Human Neurocognitive Function in the Design and Evaluation of 360 Degree Situational Awareness Display Systems (United States)


    situational awareness display systems Jason S. Metcalfe a , Thomas Mikulski b , and Scott Dittman c, a a DCS Corporation, 6909 Metro Park Dr., Suite...ADDRESS(ES) US Army RDECOM-TARDEC 6501 E 11 Mile Rd Warren, MI 48397-5000, USA DCS Corporation, 6909 Metro Park Dr, Suite 500, Alexandria, VA 22310...gigabit Ethernet architecture that supports high-definition (HD) video transmission. Internally, the platform will have three independently controlled

  12. Multiple Introductions of Zika Virus into the United States Revealed Through Genomic Epidemiology (United States)


    Multiple introductions of Zika virus into the United States revealed through genomic epidemiology Nathan D Grubaugh1*, Jason T Ladner2,*, Moritz UG...042 DISTRIBUTION STATEMENT A: Approved for public release; distribution is unlimited. UNCLASSIFIED Zika virus (ZIKV) is currently causing an... virus case data Weekly reports of international travel-associated Zika fever cases in Florida and ZIKV infected cases acquired in Florida were obtained

  13. Case series

    African Journals Online (AJOL)


    1 mai 2014 ... acidocétose diabétique dans le service de Médecine Interne de l'hôpital Jason Sendwe de Lubumbashi (République Démocratique du Congo). L'échantillon était exhaustif ... métabolique à trou anionique augmenté [1,2]. Son incidence dans le .... aura évolué vers l'installation d'un coma, faute de prise en ...

  14. Ocean Data Quality Control (United States)


    Float, Fixed /Drifting Buoy Altimeter SSH: Jason-1, Joson-2, ENVISAT Sea Ice: SSM/I, SSMIS Glider : Slocum , Sea- Glider , Spray CTD Stage 2...and salinity. Profile observations are also available from gliders that measure temperature and salinity at varying depths and positions along a...dive. A glider dive consists of a descending and an ascending profile in which the latitude, longitude positions and times of the observations change

  15. Assimilation of the AVISO Altimetry Data into the Ocean Dynamics Model with a High Spatial Resolution Using Ensemble Optimal Interpolation (EnOI) (United States)

    Kaurkin, M. N.; Ibrayev, R. A.; Belyaev, K. P.


    A parallel realization of the Ensemble Optimal Interpolation (EnOI) data assimilation (DA) method in conjunction with the eddy-resolving global circulation model is implemented. The results of DA experiments in the North Atlantic with the assimilation of the Archiving, Validation and Interpretation of Satellite Oceanographic (AVISO) data from the Jason-1 satellite are analyzed. The results of simulation are compared with the independent temperature and salinity data from the ARGO drifters.

  16. Anaerobic Metabolism of Biodiesel and Its Impact on Metal Corrosion (United States)


    Metabolism of Biodiesel and Its Impact on Metal Corrosion Deniz F. Aktas,† Jason S. Lee,‡ Brenda J. Little,‡ Richard I. Ray,‡ Irene A. Davidova...AND SUBTITLE Anaerobic Metabolism of Biodiesel and Its Impact on Metal Corrosion 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...The intensity of the blackening and distribution of deposits varied with the location within the exposure tank. All coupons exposed to seawater were

  17. Optimal management of type 2 diabetes in patients with increased risk of hypoglycemia


    Taylor, James; Anderson,Morgan; Powell,Jason; Campbell,Kendall


    Morgan Anderson,1 Jason Powell,2 Kendall M Campbell,3 James R Taylor2 1North Florida/South Georgia Veterans Health System, Malcom Randall VAMC, 2University of Florida, College of Pharmacy, Gainesville, 3The Center for Underrepresented Minorities in Academic Medicine, The Florida State University College of Medicine Tallahassee, FL, USA Abstract: With the number of individuals diagnosed with type 2 diabetes on the rise, it has become more important to ensure these patients are effectively tre...

  18. Oceanography in the formal and informal classroom (United States)

    Richardson, A.; Jasnow, M.; Srinivasan, M.; Rosmorduc, V.; Blanc, F.


    The TOPEX/Poseidon and Jason-1 ocean altimeter missions offer the educator in the middle school or informal education venue a unique opportunity for reinforcing ocean science studies. An educational poster from NASA's Jet Propulsion Laboratory and France's Centre National d'Etudes Spatiales provide teachers and students a tool to examine topics such as the dynamics of ocean circulation, ocean research, and the oceans' role in climate.

  19. In-Use and Emerging Disruptive Technology Trends (United States)


    Windows Server and the Azure cloud service. (Zander 2014) Although this cur- rently limits the utility of this particular program, it does not container technology in the market place. Major compa- nies supporting Docker include Microsoft ( Azure ), Google (Com- pute Engine), Red Hat...14, 2015) Zander, Jason. “New Windows Server containers and Azure support for Docker.” Octo- ber 15, 2014.

  20. Autonomous Exploration Using an Information Gain Metric (United States)


    navigation goals, serving to drive an autonomous system. By continually moving to these navigation goals and taking measurements, the system works to...ARL-TR-7638 ● MAR 2016 US Army Research Laboratory Autonomous Exploration Using an Information Gain Metric by Nicholas C Fung...Laboratory Autonomous Exploration Using an Information Gain Metric by Nicholas C Fung, Jason M Gregory, and John G Rogers Computational and