WorldWideScience

Sample records for spontaneous energy release

  1. Energy released in fission

    International Nuclear Information System (INIS)

    James, M.F.

    1969-05-01

    The effective energy released in and following the fission of U-235, Pu-239 and Pu-241 by thermal neutrons, and of U-238 by fission spectrum neutrons, is discussed. The recommended values are: U-235 ... 192.9 ± 0.5 MeV/fission; U-238 ... 193.9 ± 0.8 MeV/fission; Pu-239 ... 198.5 ± 0.8 MeV/fission; Pu-241 ... 200.3 ± 0.8 MeV/fission. These values include all contributions except from antineutrinos and very long-lived fission products. The detailed contributions are discussed, and inconsistencies in the experimental data are pointed out. In Appendix A, the contribution to the total useful energy release in a reactor from reactions other than fission are discussed briefly, and in Appendix B there is a discussion of the variations in effective energy from fission with incident neutron energy. (author)

  2. Norepinephrine release in arteries of spontaneously hypertensive rats

    International Nuclear Information System (INIS)

    Zsoter, T.T.; Wolchinsky, C.; Lawrin, M.; Sirko, S.

    1982-01-01

    The role of the sympathetic nervous system in arterial hypertension cannot be properly evaluated until it is known about the activity in the vessels themselves. In this study researchers investigated the effect of transmural stimulation on the tail artery - labelled in vitro with 3 H-norepinephrine - of 7-9 week old spontaneously hypertensive rats (SHR) and Wistar Kyoto controls (WKR). Electrical stimulation using two frequencies (2 and 10 Hz) resulted in significantly more 3 H overflow in vessels from SHR than from WKR. With 10 Hz stimulation the fractional release was also greater. Column chromatographic analysis of 3 H overflow revealed that transmural stimulation in arteries of SHR enhanced mainly the release of norepinephrine and not of its metabolites. Significantly, an increased release of 3 H-norepinephrine on stimulation was observed in SHR before the full development of hypertension suggesting that it might be a cause rather than a consequence of high blood pressure

  3. A Responsive Battery with Controlled Energy Release.

    Science.gov (United States)

    Wang, Xiaopeng; Gao, Jian; Cheng, Zhihua; Chen, Nan; Qu, Liangti

    2016-11-14

    A new type of responsive battery with the fascinating feature of pressure perceptibility has been developed, which can spontaneously, timely and reliably control the power outputs (e.g., current and voltage) in response to pressure changes. The device design is based on the structure of the Zn-air battery, in which graphene-coated sponge serves as pressure-sensitive air cathode that endows the whole system with the capability of self-controlled energy release. The responsive batteries exhibit superior battery performance with high open-circuit voltage (1.3 V), and competitive areal capacity of 1.25 mAh cm -2 . This work presents an important move towards next-generation intelligent energy storage devices with energy management function. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Nuclear energy release from fragmentation

    Energy Technology Data Exchange (ETDEWEB)

    Li, Cheng [The Key Laboratory of Beam Technology and Material Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Souza, S.R. [Instituto de Física, Universidade Federal do Rio de Janeiro Cidade Universitária, Caixa Postal 68528, 21945-970 Rio de Janeiro (Brazil); Tsang, M.B. [The Key Laboratory of Beam Technology and Material Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); National Superconducting Cyclotron Laboratory and Physics and Astronomy Department, Michigan State University, East Lansing, MI 48824 (United States); Zhang, Feng-Shou, E-mail: fszhang@bnu.edu.cn [The Key Laboratory of Beam Technology and Material Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Center of Theoretical Nuclear Physics, National Laboratory of Heavy Ion Accelerator of Lanzhou, Lanzhou 730000 (China)

    2016-08-15

    It is well known that binary fission occurs with positive energy gain. In this article we examine the energetics of splitting uranium and thorium isotopes into various numbers of fragments (from two to eight) with nearly equal size. We find that the energy released by splitting {sup 230,232}Th and {sup 235,238}U into three equal size fragments is largest. The statistical multifragmentation model (SMM) is applied to calculate the probability of different breakup channels for excited nuclei. By weighing the probability distributions of fragment multiplicity at different excitation energies, we find the peaks of energy release for {sup 230,232}Th and {sup 235,238}U are around 0.7–0.75 MeV/u at excitation energy between 1.2 and 2 MeV/u in the primary breakup process. Taking into account the secondary de-excitation processes of primary fragments with the GEMINI code, these energy peaks fall to about 0.45 MeV/u.

  5. The neuropeptide Gonadotropin-releasing hormone modifies the spontaneous muscular contraction in the earthworm: Eisenia foetida.

    Science.gov (United States)

    Luis Quintanar, J; Gutiérrez-García, Karina; Castillo-Hernández, Luis

    2011-12-01

    We investigated whether the Gonadotropin-releasing hormone affects the spontaneous muscular contraction in the earthworm Eisenia foetida. In addition, we investigated the presence of Gonadotropin-releasing hormone receptor in ventral nerve cord by immunohistochemistry and polymerase chain reaction. Gonadotropin-releasing hormone induced a significant increase on both amplitude and muscular tone and decrease in the frequency of spontaneous muscular contraction. We found the presence of immunoreactive material to Gonadotropin-releasing hormone receptor in the ventral nerve cord, likewise the Gonadotropin-releasing hormone receptor mRNA expression. In conclusion, the Gonadotropin-releasing hormone modifies the spontaneous muscular contraction in E. foetida and these effects can be due to the activation of the Gonadotropin-releasing hormone receptor.

  6. Differential calcium dependence in basal and forskolin-potentiated spontaneous transmitter release in basolateral amygdala neurons.

    Science.gov (United States)

    Miura, Yuki; Naka, Masamitsu; Matsuki, Norio; Nomura, Hiroshi

    2012-10-31

    Action potential-independent transmitter release, or spontaneous release, is postulated to produce multiple postsynaptic effects (e.g., maintenance of dendritic spines and suppression of local dendritic protein synthesis). Potentiation of spontaneous release may contribute to the precise modulation of synaptic function. However, the expression mechanism underlying potentiated spontaneous release remains unclear. In this study, we investigated the involvement of extracellular and intracellular calcium in basal and potentiated spontaneous release. Miniature excitatory postsynaptic currents (mEPSCs) of the basolateral amygdala neurons in acute brain slices were recorded. Forskolin, an adenylate cyclase activator, increased mEPSC frequency, and the increase lasted at least 25 min after washout. Removal of the extracellular calcium decreased mEPSC frequency in both naïve and forskolin-treated slices. On the other hand, chelation of intracellular calcium by BAPTA-AM decreased mEPSC frequency in naïve, but not in forskolin-treated slices. A blockade of the calcium-sensing receptor (CaSR) resulted in an increase in mEPSC frequency in forskolin-treated, but not in naïve slices. These findings indicate that forskolin-induced potentiation is accompanied by changes in the mechanisms underlying Ca(2+)-dependent spontaneous release. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  7. Self energy QED: Multipole spontaneous emission

    International Nuclear Information System (INIS)

    Salamin, Y.I.

    1990-08-01

    Within the context of Barut's self-field approach, we write the exact expression of the spontaneous atomic decay rate (Phys. Rev. A37, 2284 (1988)), in the long wavelength approximation, in terms of electric- and magnetic-like multipole contributions which are related to the matrix elements of the transition charge and current distributions of the relativistic electron. A number of features of these expressions are discussed and their generalization to interacting composite systems is also pointed out. (author). 8 refs

  8. Glutamate released spontaneously from astrocytes sets the threshold for synaptic plasticity.

    Science.gov (United States)

    Bonansco, Christian; Couve, Alejandro; Perea, Gertrudis; Ferradas, Carla Á; Roncagliolo, Manuel; Fuenzalida, Marco

    2011-04-01

    Astrocytes exhibit spontaneous calcium oscillations that could induce the release of glutamate as gliotransmitter in rat hippocampal slices. However, it is unknown whether this spontaneous release of astrocytic glutamate may contribute to determining the basal neurotransmitter release probability in central synapses. Using whole-cell recordings and Ca(2+) imaging, we investigated the effects of the spontaneous astrocytic activity on neurotransmission and synaptic plasticity at CA3-CA1 hippocampal synapses. We show here that the metabolic gliotoxin fluorocitrate (FC) reduces the amplitude of evoked excitatory postsynaptic currents and increases the paired-pulse facilitation, mainly due to the reduction of the neurotransmitter release probability and the synaptic potency. FC also decreased intracellular Ca(2+) signalling and Ca(2+) -dependent glutamate release from astrocytes. The addition of glutamine rescued the effects of FC over the synaptic potency; however, the probability of neurotransmitter release remained diminished. The blockage of group I metabotropic glutamate receptors mimicked the effects of FC on the frequency of miniature synaptic responses. In the presence of FC, the Ca(2+) chelator 1,2-bis(2-aminophenoxy)ethane-N,N,N ',N '-tetra-acetate or group I metabotropic glutamate receptor antagonists, the excitatory postsynaptic current potentiation induced by the spike-timing-dependent plasticity protocol was blocked, and it was rescued by delivering a stronger spike-timing-dependent plasticity protocol. Taken together, these results suggest that spontaneous glutamate release from astrocytes contributes to setting the basal probability of neurotransmitter release via metabotropic glutamate receptor activation, which could be operating as a gain control mechanism that regulates the threshold of long-term potentiation. Therefore, endogenous astrocyte activity provides a novel non-neuronal mechanism that could be critical for transferring information in

  9. Intense Terahertz Fields for Fast Energy Release

    Science.gov (United States)

    2016-11-01

    6201 Fort Belvoir, VA 22060-6201 T E C H N IC A L R E P O R T DTRA-TR-17-10 Intense Terahertz Fields for Fast Energy Release...customary unit. Grant #  HDTRA 1-12-1-0044 Intense Terahertz Fields for Fast Energy Release Final Report PI: Keith A. Nelson 617-253-1423 kanelson

  10. Alterations in Spontaneous Transmitter Release by Divalent Cations after Treatment of the Neuromuscular Junction with Alpha-Bungarotoxin

    Science.gov (United States)

    1982-01-01

    to change the spontaneous release rate of quantal acetylcholine . The simplest interpretation of these results is that toxin treatment increases the...Gage. 1973; Kita et al.. 1981), Mn increases spontaneous relese . The potentiations of transmitte- release by cobalt and nickel after toxin treatment...and Van der Kkw.. W. (1976). Effects of the ionophore X-537A on acetylcholine release at the frog neuromuscular junction. J. PuIwOl. Loand. 29 177-4

  11. Histamine release positive test associates with disease remission in chronic spontaneous urticaria

    DEFF Research Database (Denmark)

    Berti, A; Yacoub, M R; Skov, Per Stahl

    2017-01-01

    Summary: Background. Histamine release (HR) test has previously been shown to predict the presence of endogenous histamine-releasing factors in chronic spontaneous urticaria (CSU). Objectives and methods. Twenty CSU patients unresponsive to antihistamine treatment were enrolled in order to evaluate...... with a positive HR test had a significant reduction of disease activity (p = 0.003) whereas patients with a negative HR test did not (p > 0.05), leading to disease remission and antihistamine treatment withdrawal in 67% (6/9) of positive HR test patients versus 18% (2/11) of negative HR test patients (p = 0...

  12. Stored energy release behaviour of disordered carbon

    Science.gov (United States)

    Dasgupta, K.; Barat, P.; Sarkar, A.; Mukherjee, P.; Sathiyamoorthy, D.

    2007-06-01

    The use of graphite as a moderator in a low temperature thermal nuclear reactor is restricted due to accumulation of energy caused by displacement of atoms by neutrons and high energetic particles. Thermal transients may lead to a release of stored energy that may raise the temperature of the fuel clad above the design limit. Disordered carbon is thought to be an alternative choice for this purpose. Two types of disordered carbon composites, namely, CB (made up of 15 wt. % carbon black dispersed in carbonized phenolic resin) and PAN (made up of 20 vol. % chopped polyacrylonitrile carbon fibre dispersed in carbonized phenolic resin matrix) have been irradiated with 145 MeV Ne6+ ions at three fluence levels of 1.0×1013, 5.0×1013 and 1.5×1014 Ne6+/cm2, respectively. The XRD patterns revealed that both the samples remained disordered even after irradiation. The maximum release of stored energy for CB was 212 J/g and that of PAN was 906 J/g. For CB, the release of stored energy was a first order reaction with activation energy of 2.79 eV and a frequency factor of 3.72×1028 per second. 13% of the defects got annealed by heating up to 700 °C. PAN showed a third-order release rate with activation energy of 1.69 eV and a frequency factor of 1.77×1014 per second. 56% of the total defects got annealed by heating it up to 700 °C. CB seems to be the better choice than PAN as it showed less energy release with a slower rate.

  13. Omega 3 fatty acids increase spontaneous release of cytosolic components from tumor cells

    Energy Technology Data Exchange (ETDEWEB)

    Jenski, L.J.; Sturdevant, L.K.; Ehringer, W.D.; Stillwell, W. (Department of Biology, Indiana University-Purdue University, Indianapolis (United States))

    1991-05-01

    Mice fed menhaden (fish) oil or coconut oil-rich diets were inoculated intraperitoneally with a rapidly growing leukemia, T27A. After one week, the tumor cells were harvested, and 51Cr was used to label intracellular molecules. Spontaneous release of 51Cr was used as a measure of plasma membrane permeability. Compared to cells from mice fed coconut oil (rich in saturated fatty acids), tumor cells from mice fed menhaden oil (rich in long chain polyunsaturated omega 3 fatty acids) showed an increased level of spontaneous 51Cr release, which was exacerbated by increased temperature and reduced by extracellular protein. At physiological salt concentrations, the released 51Cr was detected in particles of approximately 2700 daltons. Enhanced permeability correlated with the incorporation of dietary (fish oil) omega 3 polyunsaturated fatty acids docosahexaenoic and eicosapentaenoic acid into the tumor cells. The results demonstrate that omega 3 fatty acids are incorporated into cellular constituents of tumor cells and change properties associated with the plasma membrane. This result suggests that dietary manipulation may be used to enhance tumor cell permeability and contribute to tumor eradication.

  14. Omega 3 fatty acids increase spontaneous release of cytosolic components from tumor cells

    International Nuclear Information System (INIS)

    Jenski, L.J.; Sturdevant, L.K.; Ehringer, W.D.; Stillwell, W.

    1991-01-01

    Mice fed menhaden (fish) oil or coconut oil-rich diets were inoculated intraperitoneally with a rapidly growing leukemia, T27A. After one week, the tumor cells were harvested, and 51Cr was used to label intracellular molecules. Spontaneous release of 51Cr was used as a measure of plasma membrane permeability. Compared to cells from mice fed coconut oil (rich in saturated fatty acids), tumor cells from mice fed menhaden oil (rich in long chain polyunsaturated omega 3 fatty acids) showed an increased level of spontaneous 51Cr release, which was exacerbated by increased temperature and reduced by extracellular protein. At physiological salt concentrations, the released 51Cr was detected in particles of approximately 2700 daltons. Enhanced permeability correlated with the incorporation of dietary (fish oil) omega 3 polyunsaturated fatty acids docosahexaenoic and eicosapentaenoic acid into the tumor cells. The results demonstrate that omega 3 fatty acids are incorporated into cellular constituents of tumor cells and change properties associated with the plasma membrane. This result suggests that dietary manipulation may be used to enhance tumor cell permeability and contribute to tumor eradication

  15. Slow spontaneous [Ca2+]i oscillations reflect nucleotide release from renal epithelia

    DEFF Research Database (Denmark)

    Geyti, Christine Stride; Odgaard, Elvin V. P.; Overgaard, Morten Thaarup

    2008-01-01

    Renal epithelia can be provoked mechanically to release nucleotides, which subsequently increases the intracellular Ca(2+) concentration [Ca(2+)](i) through activation of purinergic (P2) receptors. Cultured cells often show spontaneous [Ca(2+)](i) oscillations, a feature suggested to involve...... period of 1 min, 10.9 +/- 6.7% (n = 23) of the cells showed spontaneous [Ca(2+)](i) increases. Spontaneous adenosine triphosphate (ATP) release from MDCK cells was detected directly by luciferin/luciferase. Scavenging of ATP by apyrase or hexokinase markedly reduced the [Ca(2+)](i) oscillatory activity......, whereas inhibition of ecto-ATPases (ARL67156) enhanced the [Ca(2+)](i) oscillatory activity. The association between spontaneous [Ca(2+)](i) increases and nucleotide signalling was further tested in 132-1N1 cells lacking P2 receptors. These cells hardly showed any spontaneous [Ca(2+)](i) increases...

  16. Prophage spontaneous activation promotes DNA release enhancing biofilm formation in Streptococcus pneumoniae.

    Directory of Open Access Journals (Sweden)

    Margarida Carrolo

    Full Text Available Streptococcus pneumoniae (pneumococcus is able to form biofilms in vivo and previous studies propose that pneumococcal biofilms play a relevant role both in colonization and infection. Additionally, pneumococci recovered from human infections are characterized by a high prevalence of lysogenic bacteriophages (phages residing quiescently in their host chromosome. We investigated a possible link between lysogeny and biofilm formation. Considering that extracellular DNA (eDNA is a key factor in the biofilm matrix, we reasoned that prophage spontaneous activation with the consequent bacterial host lysis could provide a source of eDNA, enhancing pneumococcal biofilm development. Monitoring biofilm growth of lysogenic and non-lysogenic pneumococcal strains indicated that phage-infected bacteria are more proficient at forming biofilms, that is their biofilms are characterized by a higher biomass and cell viability. The presence of phage particles throughout the lysogenic strains biofilm development implicated prophage spontaneous induction in this effect. Analysis of lysogens deficient for phage lysin and the bacterial major autolysin revealed that the absence of either lytic activity impaired biofilm development and the addition of DNA restored the ability of mutant strains to form robust biofilms. These findings establish that limited phage-mediated host lysis of a fraction of the bacterial population, due to spontaneous phage induction, constitutes an important source of eDNA for the S. pneumoniae biofilm matrix and that this localized release of eDNA favors biofilm formation by the remaining bacterial population.

  17. High energy γ rays from 252Cf spontaneous fission

    Science.gov (United States)

    Hofman, D. J.; Back, B. B.; Montoya, C. P.; Schadmand, S.; Varma, R.; Paul, P.

    1993-03-01

    The spontaneous fission decay of 252Cf has been analyzed in a statistical model with emphasis on describing recently reported high energy γ-ray spectra. An enhanced γ emission in the range from 3 to 10 MeV which is observed for nearly symmetric mass splits is readily understood as a result of the different fragment excitation energies. The model includes a viscous motion to the scission point with the possibility of prescission γ emission. It was found that even with saddle-to-scission times of τscneutron multiplicities, prescission γ rays are overwhelmed by fragment γ rays. Thus, the recently reported strong angular anisotropy of γ rays in the range Eγ=8-12 MeV is unexplained within the present understanding of the fission process.

  18. Serpentine locomotion through elastic energy release

    OpenAIRE

    Dal Corso, Francesco; Misseroni, Diego; Pugno, Nicola; Movchan, A. B.; Movchan, N. V.; Bigoni, Davide

    2017-01-01

    A model for serpentine locomotion is derived from a novel perspective based on concepts from configurational mechanics. The motion is realized through the release of the elastic energy of a deformable rod, sliding inside a frictionless channel, which represents a snake moving against lateral restraints. A new formulation is presented, correcting previous results and including situations never analysed so far, as in the cases when the serpent's body lies only partially inside the restraining c...

  19. Assessment of chronic spontaneous urticaria by serum-induced tumor necrosis factor alpha and matrix metalloproteinase-9 release

    DEFF Research Database (Denmark)

    Falkencrone, Sidsel; Bindslev-Jensen, Carsten; Skov, Per Stahl

    BACKGROUND Previous studies from our group have demonstrated that IgE-mediated basophil activation leads to release of TNFα that in turn can induce matrix metallo-proteinase-9 (MMP-9) release from monocytes. We wished to investigate if serum from chronic spontaneous urticaria-patients with auto-a....... Release levels appeared to be positive correlated to ASST reaction in ASST+ patients but not to disease severity for CSU patients in general....

  20. The Dark Energy Survey First Data Release

    Science.gov (United States)

    Carrasco Kind, Matias

    2018-01-01

    In this talk I will announce and highlight the main components of the first public data release (DR1) coming from the Dark Energy Survey (DES).In January 2016, the DES survey made available, in a simple unofficial release to the astronomical community, the first set of products. This data was taken and studied during the DES Science Verification period consisting on roughly 250 sq. degrees and 25 million objects at a mean depth of i=23.7 that led to over 80 publications from DES scientist.The DR1 release is the first official release from the main survey and it consists on the observations taken during the first 3 seasons from August 2013 to February 2016 (about 100 nights each season) of the survey which cover the entire DES footprint. All of the Single Epoch Images and the Year 3 Coadded images distributed in 10223 tiles are available for download in this release. The catalogs provide astrometry, photometry and basic classification for near 400M objects in roughly 5000 sq. degrees on the southern hemisphere with a approximate mean depth of i=23.3. Complementary footprint, masking and depth information is also available. All of the software used during the generation of these products are open sourced and have been made available through the Github DES Organization. Images, data and other sub products have been possible through the international and collaborative effort of all 25 institutions involved in DES and are available for exploration and download through the interfaces provided by a partnership between NCSA, NOAO and LIneA.

  1. Features of the Energy Balance and Fragmentation Mechanisms at Spontaneous Failure of Class I and Class II Rocks

    Science.gov (United States)

    Tarasov, Boris G.; Stacey, Thomas R.

    2017-10-01

    Practically, all types of rockbursts are accompanied by release of seismic energy, rock bulking (due to fracturing and fragmentation), and ejection of fragmented rocks in the opening. Principles of the energy redistribution during rockbursts in some regards are comparable with principles taking place at spontaneous failure of rock specimens under compression in loading systems. In both cases, the total potential elastic energy accumulated in the failing material and in the loading system (or surrounding rock mass) is converted into such components of dynamic energy as rupture energy, seismic energy (or energy of oscillation of the loading system due to dynamic energy release), and kinetic energy of flying fragments of the failed material. It is known that spontaneous failure takes place at the post-peak failure stage and is determined by the ratio between stiffness of the loading system and stiffness (or brittleness) of the failing material. However, principles of the energy redistribution between different components of the energy balance are still unclear. The paper discusses results of laboratory experiments conducted on rock specimens of different brittleness (including Class I and Class II) that were loaded in testing machines of different loading stiffness. The most brittle of the tested specimens are represented by quartzite and glass, and the less brittle by salt. The loading stiffness of testing machines used in experiments was variable within three decimal orders of magnitude. The specific variations of the dynamic energy balance depending on rock brittleness and loading stiffness were established. The role of each portion of elastic energy stemming from the specimen and from the loading system in determining the dynamic energy balance and fragmentation mechanisms operating at spontaneous failure is analysed. The results obtained contribute to the understanding of dynamic processes taking place during rockbursts.

  2. Norepinephrine release and reuptake by hypothalamic synaptosomes of spontaneously hypertensive rats

    International Nuclear Information System (INIS)

    Hano, T.; Jeng, Y.; Rho, J.

    1989-01-01

    We compared the overflow of endogenous norepinephrine during electrical field stimulation, the norepinephrine content, and the rate of initial neuronal uptake of [3H]norepinephrine in synaptosomes isolated from hypothalamus and brainstem of spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats at 7 and 13 weeks of age. The synaptosomes of two rats, a SHR and a WKY rat control, were simultaneously processed and subjected to the same electrical field stimulation. The overflow of endogenous norepinephrine during electrical stimulation (2 Hz, 2 minutes) in the hypothalamic synaptosomes of 7-week-old SHR was significantly greater, whereas the overflow of 13-week-old SHR was equivalent to the age-matched WKY rat. The norepinephrine content of synaptosomes was about the same in SHR and age-matched controls. There was also significantly enhanced [3H]norepinephrine uptake in the hypothalamic synaptosomes of young SHR, but neither the hypothalamic nor the brainstem samples of 13-week-old SHR showed any significant difference in their rate of [3H]norepinephrine uptake. These data are similar to those we observed (unpublished observations) in perfused mesenteric artery system in which norepinephrine release was significantly elevated during periarterial nerve stimulation only in young SHR. Thus, these results suggest that a parallel enhancement of norepinephrine release in hypothalamus with that of peripheral nervous system may play an important role during development of hypertension in young SHR

  3. Energy market review releases draft report

    International Nuclear Information System (INIS)

    Anon

    2002-01-01

    The Energy Market Review Releases draft report has made recommendations consistent with the Australian Gas Association (AGA)'s submissions in a number of areas. In particular, it has endorsed: 1. the need for an independent review of the gas access regime, to address the deficiencies with current access regulation identified by the Productivity Commission's Review of the National Access Regime; 2. the need for greater upstream gas market competition; 3. the principle that significant regulatory decisions should be subject to clear merits and judicial review; and 4. the need to avoid restrictions on retail energy prices. The report also endorses the need for a 'technology neutral' approach to greenhouse emissions abatement policy. It states that 'many of the current measures employed to reduce greenhouse gas emissions are poorly targeted', and that they 'target technologies or fuel types rather than greenhouse gas abatement.' Additionally, it explicitly recognises the key conclusions of the AGA's recently-released Research Paper, Reducing Greenhouse Emissions from Water Heating: Natural Gas as a Cost-effective Option. The draft report recommends the development of an economy-wide emissions trading system, to achieve a more cost-effective approach to greenhouse abatement

  4. The Dark Energy Survey Data Release 1

    Energy Technology Data Exchange (ETDEWEB)

    Abbott, T.M.C.; et al.

    2018-01-09

    We describe the first public data release of the Dark Energy Survey, DES DR1, consisting of reduced single epoch images, coadded images, coadded source catalogs, and associated products and services assembled over the first three years of DES science operations. DES DR1 is based on optical/near-infrared imaging from 345 distinct nights (August 2013 to February 2016) by the Dark Energy Camera mounted on the 4-m Blanco telescope at Cerro Tololo Inter-American Observatory in Chile. We release data from the DES wide-area survey covering ~5,000 sq. deg. of the southern Galactic cap in five broad photometric bands, grizY. DES DR1 has a median delivered point-spread function of g = 1.12, r = 0.96, i = 0.88, z = 0.84, and Y = 0.90 arcsec FWHM, a photometric precision of < 1% in all bands, and an astrometric precision of 151 mas. The median coadded catalog depth for a 1.95" diameter aperture at S/N = 10 is g = 24.33, r = 24.08, i = 23.44, z = 22.69, and Y = 21.44 mag. DES DR1 includes nearly 400M distinct astronomical objects detected in ~10,000 coadd tiles of size 0.534 sq. deg. produced from ~39,000 individual exposures. Benchmark galaxy and stellar samples contain ~310M and ~ 80M objects, respectively, following a basic object quality selection. These data are accessible through a range of interfaces, including query web clients, image cutout servers, jupyter notebooks, and an interactive coadd image visualization tool. DES DR1 constitutes the largest photometric data set to date at the achieved depth and photometric precision.

  5. Stochastic spontaneous calcium release events and sodium channelopathies promote ventricular arrhythmias

    Science.gov (United States)

    Campos, Fernando O.; Shiferaw, Yohannes; Vigmond, Edward J.; Plank, Gernot

    2017-09-01

    Premature ventricular complexes (PVCs), the first initiating beats of a variety of cardiac arrhythmias, have been associated with spontaneous calcium release (SCR) events at the cell level. However, the mechanisms underlying the degeneration of such PVCs into arrhythmias are not fully understood. The objective of this study was to investigate the conditions under which SCR-mediated PVCs can lead to ventricular arrhythmias. In particular, we sought to determine whether sodium (Na+) current loss-of-function in the structurally normal ventricles provides a substrate for unidirectional conduction block and reentry initiated by SCR-mediated PVCs. To achieve this goal, a stochastic model of SCR was incorporated into an anatomically accurate compute model of the rabbit ventricles with the His-Purkinje system (HPS). Simulations with reduced Na+ current due to a negative-shift in the steady-state channel inactivation showed that SCR-mediated delayed afterdepolarizations led to PVC formation in the HPS, where the electrotonic load was lower, conduction block, and reentry in the 3D myocardium. Moreover, arrhythmia initiation was only possible when intrinsic electrophysiological heterogeneity in action potential within the ventricles was present. In conclusion, while benign in healthy individuals SCR-mediated PVCs can lead to life-threatening ventricular arrhythmias when combined with Na+ channelopathies.

  6. Building an Efficient Model for Afterburn Energy Release

    Energy Technology Data Exchange (ETDEWEB)

    Alves, S; Kuhl, A; Najjar, F; Tringe, J; McMichael, L; Glascoe, L

    2012-02-03

    Many explosives will release additional energy after detonation as the detonation products mix with the ambient environment. This additional energy release, referred to as afterburn, is due to combustion of undetonated fuel with ambient oxygen. While the detonation energy release occurs on a time scale of microseconds, the afterburn energy release occurs on a time scale of milliseconds with a potentially varying energy release rate depending upon the local temperature and pressure. This afterburn energy release is not accounted for in typical equations of state, such as the Jones-Wilkins-Lee (JWL) model, used for modeling the detonation of explosives. Here we construct a straightforward and efficient approach, based on experiments and theory, to account for this additional energy release in a way that is tractable for large finite element fluid-structure problems. Barometric calorimeter experiments have been executed in both nitrogen and air environments to investigate the characteristics of afterburn for C-4 and other materials. These tests, which provide pressure time histories, along with theoretical and analytical solutions provide an engineering basis for modeling afterburn with numerical hydrocodes. It is toward this end that we have constructed a modified JWL equation of state to account for afterburn effects on the response of structures to blast. The modified equation of state includes a two phase afterburn energy release to represent variations in the energy release rate and an afterburn energy cutoff to account for partial reaction of the undetonated fuel.

  7. Presynaptic inhibition of spontaneous acetylcholine release induced by adenosine at the mouse neuromuscular junction.

    Science.gov (United States)

    De Lorenzo, Silvana; Veggetti, Mariela; Muchnik, Salomón; Losavio, Adriana

    2004-05-01

    1. At the mouse neuromuscular junction, adenosine (AD) and the A(1) agonist 2-chloro-N(6)-cyclopentyl-adenosine (CCPA) induce presynaptic inhibition of spontaneous acetylcholine (ACh) release by activation of A(1) AD receptors through a mechanism that is still unknown. To evaluate whether the inhibition is mediated by modulation of the voltage-dependent calcium channels (VDCCs) associated with tonic secretion (L- and N-type VDCCs), we measured the miniature end-plate potential (mepp) frequency in mouse diaphragm muscles. 2. Blockade of VDCCs by Cd(2+) prevented the effect of the CCPA. Nitrendipine (an L-type VDCC antagonist) but not omega-conotoxin GVIA (an N-type VDCC antagonist) blocked the action of CCPA, suggesting that the decrease in spontaneous mepp frequency by CCPA is associated with an action on L-type VDCCs only. 3. As A(1) receptors are coupled to a G(i/o) protein, we investigated whether the inhibition of PKA or the activation of PKC is involved in the presynaptic inhibition mechanism. Neither N-(2[p-bromocinnamylamino]-ethyl)-5-isoquinolinesulfonamide (H-89, a PKA inhibitor), nor 1-(5-isoquinolinesulfonyl)-2-methyl-piperazine (H-7, a PKC antagonist), nor phorbol 12-myristate 13-acetate (PHA, a PKC activator) modified CCPA-induced presynaptic inhibition, suggesting that these second messenger pathways are not involved. 4. The effect of CCPA was eliminated by the calmodulin antagonist N-(6-aminohexil)-5-chloro-1-naphthalenesulfonamide hydrochloride (W-7) and by ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid-acetoxymethyl ester epsilon6TDelta-BM, which suggests that the action of CCPA to modulate L-type VDCCs may involve Ca(2+)-calmodulin. 5. To investigate the action of CCPA on diverse degrees of nerve terminal depolarization, we studied its effect at different external K(+) concentrations. The effect of CCPA on ACh secretion evoked by 10 mm K(+) was prevented by the P/Q-type VDCC antagonist omega-agatoxin IVA. 6. CCPA failed to

  8. A positive serum basophil histamine release assay is a marker for ciclosporin-responsiveness in patients with chronic spontaneous urticaria

    DEFF Research Database (Denmark)

    Iqbal, Kamran; Bhargava, Kapil; Skov, Per Stahl

    2012-01-01

    ABSTRACT: The electronic records of 398 patients with chronic spontaneous urticaria (CSU) who had had a serum basophil histamine release assay (BHRA) performed as a marker of functional autoantibodies were audited. The BHRA was positive in 105 patients (26.4%). Fifty eight were treated with ciclo...... with ciclosporin because they were H1 anti-histamine unresponsive. CSU patients with a positive BHRA were more likely to respond clinically (P...

  9. Spontaneous Detachment of Colloids from Primary Energy Minima by Brownian Diffusion.

    Directory of Open Access Journals (Sweden)

    Zhan Wang

    Full Text Available The Derjaguin-Landau-Verwey-Overbeek (DLVO interaction energy profile has been frequently used to interpret the mechanisms controlling colloid attachment/detachment and aggregation/disaggregation behavior. This study highlighted a type of energy profile that is characterized by a shallow primary energy well (i.e., comparable to the average kinetic energy of a colloid at a small separation distance and a monotonic decrease of interaction energy with separation distance beyond the primary energy well. This energy profile is present due to variations of height, curvature, and density of discrete physical heterogeneities on collector surfaces. The energy profile indicates that colloids can be spontaneously detached from the shallow primary energy well by Brownian diffusion. The spontaneous detachment from primary minima was unambiguously confirmed by conducting laboratory column transport experiments involving flow interruptions for two model colloids (polystyrene latex microspheres and engineered nanoparticles (fullerene C60 aggregates. Whereas the spontaneous detachment has been frequently attributed to attachment in secondary minima in the literature, our study indicates that the detached colloids could be initially attached at primary minima. Our study further suggests that the spontaneous disaggregation from primary minima is more significant than spontaneous detachment because the primary minimum depth between colloid themselves is lower than that between a colloid and a collector surface.

  10. Spontaneous Detachment of Colloids from Primary Energy Minima by Brownian Diffusion.

    Science.gov (United States)

    Wang, Zhan; Jin, Yan; Shen, Chongyang; Li, Tiantian; Huang, Yuanfang; Li, Baoguo

    2016-01-01

    The Derjaguin-Landau-Verwey-Overbeek (DLVO) interaction energy profile has been frequently used to interpret the mechanisms controlling colloid attachment/detachment and aggregation/disaggregation behavior. This study highlighted a type of energy profile that is characterized by a shallow primary energy well (i.e., comparable to the average kinetic energy of a colloid) at a small separation distance and a monotonic decrease of interaction energy with separation distance beyond the primary energy well. This energy profile is present due to variations of height, curvature, and density of discrete physical heterogeneities on collector surfaces. The energy profile indicates that colloids can be spontaneously detached from the shallow primary energy well by Brownian diffusion. The spontaneous detachment from primary minima was unambiguously confirmed by conducting laboratory column transport experiments involving flow interruptions for two model colloids (polystyrene latex microspheres) and engineered nanoparticles (fullerene C60 aggregates). Whereas the spontaneous detachment has been frequently attributed to attachment in secondary minima in the literature, our study indicates that the detached colloids could be initially attached at primary minima. Our study further suggests that the spontaneous disaggregation from primary minima is more significant than spontaneous detachment because the primary minimum depth between colloid themselves is lower than that between a colloid and a collector surface.

  11. New Perspectives on Spontaneous Brain Activity: Dynamic Networks and Energy Matter

    Science.gov (United States)

    Tozzi, Arturo; Zare, Marzieh; Benasich, April A.

    2016-01-01

    Spontaneous brain activity has received increasing attention as demonstrated by the exponential rise in the number of published article on this topic over the last 30 years. Such “intrinsic” brain activity, generated in the absence of an explicit task, is frequently associated with resting-state or default-mode networks (DMN)s. The focus on characterizing spontaneous brain activity promises to shed new light on questions concerning the structural and functional architecture of the brain and how they are related to “mind”. However, many critical questions have yet to be addressed. In this review, we focus on a scarcely explored area, specifically the energetic requirements and constraints of spontaneous activity, taking into account both thermodynamical and informational perspectives. We argue that the “classical” definitions of spontaneous activity do not take into account an important feature, that is, the critical thermodynamic energetic differences between spontaneous and evoked brain activity. Spontaneous brain activity is associated with slower oscillations compared with evoked, task-related activity, hence it exhibits lower levels of enthalpy and “free-energy” (i.e., the energy that can be converted to do work), thus supporting noteworthy thermodynamic energetic differences between spontaneous and evoked brain activity. Increased spike frequency during evoked activity has a significant metabolic cost, consequently, brain functions traditionally associated with spontaneous activity, such as mind wandering, require less energy that other nervous activities. We also review recent empirical observations in neuroscience, in order to capture how spontaneous brain dynamics and mental function can be embedded in a non-linear dynamical framework, which considers nervous activity in terms of phase spaces, particle trajectories, random walks, attractors and/or paths at the edge of the chaos. This takes us from the thermodynamic free-energy, to the realm

  12. Key figures for energy. Release 2012

    International Nuclear Information System (INIS)

    2012-12-01

    Maps, graphs and tables illustrate the share of energy in the French economy (contributions of energy industries to the GDP), the monthly and annual evolution of gas and oil prices, the evolution of public opinion on nuclear energy, the energy bill evolutions (per energy type, with respect to GDP, imported crude oil price), the assessment of energy in France (production, imports, exports, consumption by different sectors, share of primary energy consumption per energy type), the French energy mix in 2011, the evolution of energy production and consumption per energy type and per sector. Then, this report addresses the different energy types: coal (production, thermal power plants, evolution of consumption per sector, of imports), oil (evolution of production, of global consumption and per sector, evolution of consumption of refined oil products and of automotive fuels, including agro-fuels, evolution of imports and bill), gas (transport, storage, compression and production sites and networks, natural gas production and consumption, imports), electricity (gross production, conventional thermal production, global assessment, consumption, nuclear sites, imports and exports, volume of radioactive wastes produced in 2010), renewable energies (total production and per sector, share in electricity consumption, evolution of wind energy, of wood consumption, of energy produced from renewable urban wastes, and solar energy), heat networks (evolution of consumption, of the number of networks). The last parts address the rational use of energy (energy intensity, evolution of GDP and energy consumption, evolution of car fuel consumption and CO 2 emissions), the evolution of energy prices, the relationship between energy and environment (CO 2 emissions)

  13. Key figures of renewable energies - Release 2015

    International Nuclear Information System (INIS)

    Carrier, Thelma; Collet, Isabelle; Louati, Sami; Reynaud, Didier; Monnoyer-Smith, Laurence

    2015-12-01

    This publication gathers numerous graphs and tables of data and statistics on renewable energies. After a presentation of various data which characterize and illustrate the share of renewable energies in the French energy mix, production and consumption, the production of renewable energies in metropolitan France and in overseas territories, data are presented regarding renewable hydraulics, wind energy, photovoltaic and thermal solar energy, heat pumps, solid biomass, waste-based energy production, biogas and bio-fuels. The next chapters propose an overview of the present situation and of objectives for 2020, and European and international comparisons

  14. Innervation by a GABAergic neuron depresses spontaneous release in glutamatergic neurons and unveils the clamping phenotype of synaptotagmin-1

    DEFF Research Database (Denmark)

    Wierda, Keimpe D B; Sørensen, Jakob Balslev

    2014-01-01

    from mice cultured on astrocyte islands with "homotypic" glutamatergic or GABAergic pairs and autaptic neurons. We measured mEPSC and mIPSC frequencies simultaneously from both neurons. Neuronal pairs formed both interneuronal synaptic and autaptic connections indiscriminately. We find that whereas m......EPSC and mIPSC frequencies did not deviate between autaptic and synaptic connections, the frequency of mEPSCs in mixed pairs was strongly depressed compared with either autaptic neurons or glutamatergic pairs. Simultaneous imaging of synapses, or comparison to evoked release amplitudes, showed......EPSC frequencies were increased by a factor of four in the synaptotagmin-1-null neurons, which is in line with data obtained from mixed cultures. The effect persisted after incubation with BAPTA-AM. We conclude that spontaneous GABA release exerts control over mEPSC release, and GABAergic innervation...

  15. The Relevance of AgRP Neuron-Derived GABA Inputs to POMC Neurons Differs for Spontaneous and Evoked Release.

    Science.gov (United States)

    Rau, Andrew R; Hentges, Shane T

    2017-08-02

    Hypothalamic agouti-related peptide (AgRP) neurons potently stimulate food intake, whereas proopiomelanocortin (POMC) neurons inhibit feeding. Whether AgRP neurons exert their orexigenic actions, at least in part, by inhibiting anorexigenic POMC neurons remains unclear. Here, the connectivity between GABA-releasing AgRP neurons and POMC neurons was examined in brain slices from male and female mice. GABA-mediated spontaneous IPSCs (sIPSCs) in POMC neurons were unaffected by disturbing GABA release from AgRP neurons either by cell type-specific deletion of the vesicular GABA transporter or by expression of botulinum toxin in AgRP neurons to prevent vesicle-associated membrane protein 2-dependent vesicle fusion. Additionally, there was no difference in the ability of μ-opioid receptor (MOR) agonists to inhibit sIPSCs in POMC neurons when MORs were deleted from AgRP neurons, and activation of the inhibitory designer receptor hM4Di on AgRP neurons did not affect sIPSCs recorded from POMC neurons. These approaches collectively indicate that AgRP neurons do not significantly contribute to the strong spontaneous GABA input to POMC neurons. Despite these observations, optogenetic stimulation of AgRP neurons reliably produced evoked IPSCs in POMC neurons, leading to the inhibition of POMC neuron firing. Thus, AgRP neurons can potently affect POMC neuron function without contributing a significant source of spontaneous GABA input to POMC neurons. Together, these results indicate that the relevance of GABAergic inputs from AgRP to POMC neurons is state dependent and highlight the need to consider different types of transmitter release in circuit mapping and physiologic regulation. SIGNIFICANCE STATEMENT Agouti-related peptide (AgRP) neurons play an important role in driving food intake, while proopiomelanocortin (POMC) neurons inhibit feeding. Despite the importance of these two well characterized neuron types in maintaining metabolic homeostasis, communication between these

  16. Key figures on renewable energies - Release 2013

    International Nuclear Information System (INIS)

    Louati, Sami; Reynaud, Didier; Thienard, Helene

    2013-06-01

    This publication presents and briefly discusses figures (tables and graphs giving data and their evolution over the past years until 2011) for France and its overseas territories about the energy mix, the shares of the different renewable energies (wood, wind, heat pumps, biofuels, hydraulic, solar and others), the production of renewable electricity, the primary consumption of thermal renewable energies per sector (household and office building, industry, agriculture, transport) and per energy sector. A second part addresses the different renewable energies (hydraulic, wind, photovoltaic and thermal solar, heat pumps, wood, biogas, biofuels), indicates installed powers per district or region, their production level and the corresponding evolutions over the past years. A third part addresses the objectives for 2020, compares them with the current situation and outlines the possible biases in 2011 in terms of production and consumption. A fourth part presents graphs comparing data between countries in Europe and in the world in terms of production and consumption (share of renewable energies, electricity production)

  17. Variation of kinetic energy release with temperature and electron energy for unimolecular ionic transitions

    International Nuclear Information System (INIS)

    Rabia, M.A.; Fahmy, M.A.

    1992-01-01

    The kinetic energy released during seven unimolecular ionic transitions, generated from benzyl alcohol and benzyl amine have been studied as a function of ion source temperature and ionizing electron energy. Only, the kinetic energy released during H CN elimination from fragment [C 7 H 8 N]+ ion of benzyl amine displays a temperature dependence. For only two transitions, generated from benzyl alcohol, the kinetic energy released show a significant ionizing electron energy dependence. These results may reveal the role of the internal energy of reacting ions in producing the kinetic energy released some transitions produced from benzyl alcohol

  18. Analytical Determination of Energy Release in a Coal Mass

    Directory of Open Access Journals (Sweden)

    Chengguo Zhang

    2018-01-01

    Full Text Available In underground mining, it is not currently feasible to forecast a coal burst incident. A coal burst usually includes suddenly abrupt energy release in line with the significant deformed shape in a coal mass as well as coal ejection. The major source of the released energy is the energy stored in the coal. The effect of geological characteristics in the coal on the possible released energy due to material and joint damping is classified as a current silent issue. Therefore, innovative research is needed to understand the influence of coal’s joint and cleat characters (directions and densities on the possible energy release and/or dissipation. A simple and novel analytical solution is developed in this paper to calculate the amount of released energy due to varying joint density. A broad validation is conducted by comparing the outcomes of the developed analytical model with the results of a three-dimensional numerical simulation using the commercial discrete element package 3DEC. An appropriate agreement has been observed between the results from the numerical modelling and the suggested closed form solution. The paper derives a novel analytical solution to calculate the amount of released energy in coal with different joint densities.

  19. TES (Thermal Energy Storage) Video News Release

    Science.gov (United States)

    1994-01-01

    TES is an in-space technology experiment that flew on STS-62. Its intent is to investigate the behavior of two different thermal energy storage materials as they undergo repeated melting and freezing in the microgravity environment.

  20. Theoretical physics: Quarks fuse to release energy

    Science.gov (United States)

    Miller, Gerald A.

    2017-11-01

    In nuclear fusion, energy is produced by the rearrangement of protons and neutrons. The discovery of an analogue of this process involving particles called quarks has implications for both nuclear and particle physics. See Letter p.89

  1. Elastic energy release in great earthquakes and eruptions

    Directory of Open Access Journals (Sweden)

    Agust eGudmundsson

    2014-05-01

    Full Text Available The sizes of earthquakes are measured using well-defined, measurable quantities such as seismic moment and released (transformed elastic energy. No similar measures exist for the sizes of volcanic eruptions, making it difficult to compare the energies released in earthquakes and eruptions. Here I provide a new measure of the elastic energy (the potential mechanical energy associated with magma chamber rupture and contraction (shrinkage during an eruption. For earthquakes and eruptions, elastic energy derives from two sources: (1 the strain energy stored in the volcano/fault zone before rupture, and (2 the external applied load (force, pressure, stress, displacement on the volcano/fault zone. From thermodynamic considerations it follows that the elastic energy released or transformed (dU during an eruption is directly proportional to the excess pressure (pe in the magma chamber at the time of rupture multiplied by the volume decrease (-dVc of the chamber, so that . This formula can be used as a basis for a new eruption magnitude scale, based on elastic energy released, which can be related to the moment-magnitude scale for earthquakes. For very large eruptions (>100 km3, the volume of the feeder-dike is negligible, so that the decrease in chamber volume during an eruption corresponds roughly to the associated volume of erupted materials , so that the elastic energy is . Using a typical excess pressures of 5 MPa, it is shown that the largest known eruptions on Earth, such as the explosive La Garita Caldera eruption (27-28 million years ago and largest single (effusive Colombia River basalt lava flows (15-16 million years ago, both of which have estimated volumes of about 5000 km3, released elastic energy of the order of 10EJ. For comparison, the seismic moment of the largest earthquake ever recorded, the M9.5 1960 Chile earthquake, is estimated at 100 ZJ and the associated elastic energy release at 10EJ.

  2. BDNF-Induced Potentiation of Spontaneous Twitching in Innervated Myocytes Requires Calcium Release From Intracellular Stores

    Science.gov (United States)

    KLEIMAN, ROBIN J.; TIAN, NING; KRIZAJ, DAVID; HWANG, THOMAS N.; COPENHAGEN, DAVID R.; REICHARDT, LOUIS F.

    2009-01-01

    Brain-derived neurotrophic factor (BDNF) can potentiate synaptic release at newly developed frog neuromuscular junctions. Although this potentiation depends on extracellular Ca2+ and reflects changes in acetylcholine release, little is known about the intracellular transduction or calcium signaling pathways. We have developed a video assay for neurotrophin-induced potentiation of myocyte twitching as a measure of potentiation of synaptic activity. We use this assay to show that BDNF-induced synaptic potentiation is not blocked by cadmium, indicating that Ca2+ influx through voltage-gated Ca2+ channels is not required. TrkB autophosphorylation is not blocked in Ca2+-free conditions, indicating that TrkB activity is not Ca2+ dependent. Additionally, an inhibitor of phospholipase C interferes with BDNF-induced potentiation. These results suggest that activation of the TrkB receptor activates phospholipase C to initiate intracellular Ca2+ release from stores which subsequently potentiates transmitter release. PMID:10899220

  3. Spontaneous symmetry breaking and self-consistent equations for the free-energy

    International Nuclear Information System (INIS)

    Lovesey, S.W.

    1980-03-01

    A variational procedure for the free-energy is used to derive self-consistent equations that allow for spontaneous symmetry breaking. For an N-component phi 4 -model the equations are identical to those obtained by summing all loops to order 1/N. (author)

  4. Dike propagation energy balance from deformation modeling and seismic release

    Science.gov (United States)

    Bonaccorso, Alessandro; Aoki, Yosuke; Rivalta, Eleonora

    2017-06-01

    Magma is transported in the crust mainly by dike intrusions. In volcanic areas, dikes can ascend toward the free surface and also move by lateral propagation, eventually feeding flank eruptions. Understanding dike mechanics is a key to forecasting the expected propagation and associated hazard. Several studies have been conducted on dike mechanisms and propagation; however, a less in-depth investigated aspect is the relation between measured dike-induced deformation and the seismicity released during its propagation. We individuated a simple x that can be used as a proxy of the expected mechanical energy released by a propagating dike and is related to its average thickness. For several intrusions around the world (Afar, Japan, and Mount Etna), we correlate such mechanical energy to the seismic moment released by the induced earthquakes. We obtain an empirical law that quantifies the expected seismic energy released before arrest. The proposed approach may be helpful to predict the total seismic moment that will be released by an intrusion and thus to control the energy status during its propagation and the time of dike arrest.Plain Language SummaryDike propagation is a dominant mechanism for magma ascent, transport, and eruptions. Besides being an intriguing physical process, it has critical hazard implications. After the magma intrusion starts, it is difficult to predict when and where a specific horizontal dike is going to halt and what its final length will be. In our study, we singled an equation that can be used as a proxy of the expected mechanical energy to be released by the opening dike. We related this expected energy to the seismic moment of several eruptive intrusions around the world (Afar region, Japanese volcanoes, and Mount Etna). The proposed novel approach is helpful to estimate the total seismic moment to be released, therefore allowing potentially predicting when the dike will end its propagation. The approach helps answer one of the

  5. Presynaptic inhibition of spontaneous acetylcholine release mediated by P2Y receptors at the mouse neuromuscular junction.

    Science.gov (United States)

    De Lorenzo, S; Veggetti, M; Muchnik, S; Losavio, A

    2006-09-29

    At the neuromuscular junction, ATP is co-released with the neurotransmitter acetylcholine (ACh) and once in the synaptic space, it is degraded to the presynaptically active metabolite adenosine. Intracellular recordings were performed on diaphragm fibers of CF1 mice to determine the action of extracellular ATP (100 muM) and the slowly hydrolysable ATP analog 5'-adenylylimidodiphosphate lithium (betagamma-imido ATP) (30 muM) on miniature end-plate potential (MEPP) frequency. We found that application of ATP and betagamma-imido ATP decreased spontaneous secretion by 45.3% and 55.9% respectively. 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX), a selective A(1) adenosine receptor antagonist and alpha,beta-methylene ADP sodium salt (alphabeta-MeADP), which is an inhibitor of ecto-5'-nucleotidase, did not prevent the inhibitory effect of ATP, demonstrating that the nucleotide is able to modulate spontaneous ACh release through a mechanism independent of the action of adenosine. Blockade of Ca(2+) channels by both, Cd(2+) or the combined application of nitrendipine and omega-conotoxin GVIA (omega-CgTx) (L-type and N-type Ca(2+) channel antagonists, respectively) prevented the effect of betagamma-imido ATP, indicating that the nucleotide modulates Ca(2+) influx through the voltage-dependent Ca(2+) channels related to spontaneous secretion. betagamma-Imido ATP-induced modulation was antagonized by the non-specific P2 receptor antagonist suramin and the P2Y receptor antagonist 1-amino-4-[[4-[[4-chloro-6-[[3(or4)-sulfophenyl] amino]-1,3,5-triazin-2-yl]amino]-3-sulfophenyl] amino]-9,10-dihydro-9,10-dioxo-2-anthracenesulfonic acid (reactive blue-2), but not by pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt (PPADS), which has a preferential antagonist effect on P2X receptors. Pertussis toxin and N-ethylmaleimide (NEM), which are blockers of G(i/o) proteins, prevented the action of the nucleotide, suggesting that the effect is mediated by P2Y receptors

  6. Effect of exercise training on Ca{sup 2+} release units of left ventricular myocytes of spontaneously hypertensive rats

    Energy Technology Data Exchange (ETDEWEB)

    Carneiro-Júnior, M.A. [Universidade Federal do Espírito Santo, Departamento de Ciências Fisiológicas, Vitória, ES (Brazil); Universidade Federal de Viçosa, Laboratório de Biologia do Exercício, Departamento de Educação Física, Viçosa, MG (Brazil); Quintão-Júnior, J.F.; Drummond, L.R.; Lavorato, V.N.; Drummond, F.R. [Universidade Federal de Viçosa, Laboratório de Biologia do Exercício, Departamento de Educação Física, Viçosa, MG (Brazil); Amadeu, M.A.; Oliveira, E.M. [Universidade de São Paulo, Laboratório de Bioquímica e Biologia Molecular do Exercício, Escola de Educação Física e Esportes, São Paulo, SP (Brazil); Felix, L.B. [Universidade Federal de Viçosa, Departamento de Engenharia Elétrica, Viçosa, MG (Brazil); Cruz, J.S. [Universidade Federal de Minas Gerais, Laboratório de Membranas Excitáveis e Biologia Cardiovascular, Departamento de Bioquímica e Imunologia, Belo Horizonte, MG (Brazil); Mill, J.G. [Universidade Federal do Espírito Santo, Departamento de Ciências Fisiológicas, Vitória, ES (Brazil); Natali, A.J.; Prímola-Gomes, T.N. [Universidade Federal de Viçosa, Laboratório de Biologia do Exercício, Departamento de Educação Física, Viçosa, MG (Brazil)

    2014-08-29

    In cardiomyocytes, calcium (Ca{sup 2+}) release units comprise clusters of intracellular Ca{sup 2+} release channels located on the sarcoplasmic reticulum, and hypertension is well established as a cause of defects in calcium release unit function. Our objective was to determine whether endurance exercise training could attenuate the deleterious effects of hypertension on calcium release unit components and Ca{sup 2+} sparks in left ventricular myocytes of spontaneously hypertensive rats. Male Wistar and spontaneously hypertensive rats (4 months of age) were divided into 4 groups: normotensive (NC) and hypertensive control (HC), and normotensive (NT) and hypertensive trained (HT) animals (7 rats per group). NC and HC rats were submitted to a low-intensity treadmill running protocol (5 days/week, 1 h/day, 0% grade, and 50-60% of maximal running speed) for 8 weeks. Gene expression of the ryanodine receptor type 2 (RyR2) and FK506 binding protein (FKBP12.6) increased (270%) and decreased (88%), respectively, in HC compared to NC rats. Endurance exercise training reversed these changes by reducing RyR2 (230%) and normalizing FKBP12.6 gene expression (112%). Hypertension also increased the frequency of Ca{sup 2+} sparks (HC=7.61±0.26 vs NC=4.79±0.19 per 100 µm/s) and decreased its amplitude (HC=0.260±0.08 vs NC=0.324±0.10 ΔF/F{sub 0}), full width at half-maximum amplitude (HC=1.05±0.08 vs NC=1.26±0.01 µm), total duration (HC=11.51±0.12 vs NC=14.97±0.24 ms), time to peak (HC=4.84±0.06 vs NC=6.31±0.14 ms), and time constant of decay (HC=8.68±0.12 vs NC=10.21±0.22 ms). These changes were partially reversed in HT rats (frequency of Ca{sup 2+} sparks=6.26±0.19 µm/s, amplitude=0.282±0.10 ΔF/F{sub 0}, full width at half-maximum amplitude=1.14±0.01 µm, total duration=13.34±0.17 ms, time to peak=5.43±0.08 ms, and time constant of decay=9.43±0.15 ms). Endurance exercise training attenuated the deleterious effects of hypertension on calcium release units of

  7. α2-Adrenoreceptor Constraint of Catecholamine Release and Blood Pressure Is Enhanced in Female Spontaneously Hypertensive Rats.

    Science.gov (United States)

    Berg, Torill

    2016-01-01

    α2-adrenoceptors (α2AR) lower central sympathetic output and peripheral catecholamine release, and may therefore prevent sympathetic hyperactivity and hypertension. The α2AR are dysfunctional in male spontaneously hypertensive rats (SHR). Premenopausal females are less hypertensive than males. The purpose of this study was to test if this difference could be explained by functional α2AR in the female SHR. A 15-min tyramine-infusion was used to stimulate norepinephrine release through the re-uptake transporter, consequently preventing re-uptake. Presynaptic control of vesicular release will therefore be reflected as differences in overflow to plasma. The surgical trauma activates secretion of epinephrine, also subjected to α2AR auto-inhibition. Blood pressure was monitored through a femoral artery catheter and cardiac output by ascending aorta flow in 12-14 weeks-old (early hypertension) SHR and normotensive rats (WKY). Total peripheral vascular resistance (TPR) was calculated. Female SHR, unlike male, were close to normotensive. Pre-treatment with none-selective (clonidine) or non-A-selective (ST-91) α2AR agonist reduced, and none-selective α2AR antagonist (L-659,066) increased tyramine-induced norepinephrine overflow in female WKY and SHR. L-659,066 also increased secretion of epinephrine. The L-659,066-induced increase in catecholamine release was further enhanced by additional pre-treatment with ST-91 or angiotensin AT1 receptor antagonist (losartan) in SHR only. L-659,066 eliminated the tyramine-induced rise in TPR in both strains in female rats. α2AR-mediated control of catecholamine release and vascular tension was therefore functional in female SHR, unlike that previously observed in male SHR. Functional α2AR is likely to have a protective function and may explain the lack of hypertension in the young female SHR.

  8. α2-ADRENOCEPTOR CONSTRAINT OF CATECHOLAMINE RELEASE AND BLOOD PRESSURE IS ENHANCED IN FEMALE SPONTANEOUSLY HYPERTENSIVE RATS

    Directory of Open Access Journals (Sweden)

    Torill eBerg

    2016-03-01

    Full Text Available α2-adrenoceptors (α2AR lower central sympathetic output and peripheral catecholamine release, and may therefore prevent sympathetic hyperactivity and hypertension. The α2AR are dysfunctional in male spontaneously hypertensive rats (SHR. Premenopausal females are less hypertensive than males. The purpose of this study was to test if this difference could be explained by functional α2AR in the female SHR. A 15-min tyramine-infusion was used to stimulate norepinephrine release through the re-uptake transporter, consequently preventing re-uptake. Presynaptic control of vesicular release will therefore be reflected as differences in overflow to plasma. The surgical trauma activates secretion of epinephrine, also subjected to α2AR auto-inhibition. Blood pressure was monitored through a femoral artery catheter and cardiac output by ascending aorta flow in 12-14 weeks-old (early hypertension SHR and normotensive rats (WKY. Total peripheral vascular resistance (TPR was calculated. Female SHR, unlike male, were close to normotensive. Pre-treatment with none-selective (clonidine or non-A-selective (ST-91 α2AR agonist reduced, and none-selective α2AR antagonist (L-659,066 increased tyramine-induced norepinephrine overflow in female and WKY and SHR. L-659,066 also increased secretion of epinephrine. The L-659,066-induced increase in catecholamine release was further enhanced by additional pre-treatment with ST-91 or angiotensin AT1 receptor antagonist (losartan in SHR only. L-659,066 eliminated the tyramine-induced rise in TPR in both strains in female rats. Conclusion: α2AR-mediated control of catecholamine release and vascular tension was therefore functional in female SHR, unlike that previously observed in male SHR. Functional α2AR is likely to have a protective function and may explain the lack of hypertension in the young female SHR.

  9. Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures

    LENUS (Irish Health Repository)

    Nic An Ultaigh, Sinead

    2011-02-23

    Abstract Introduction The aim of this study was to examine the effect of blocking Toll-like receptor 2 (TLR2) in rheumatoid arthritis (RA) synovial cells. Methods RA synovial tissue biopsies, obtained under direct visualization at arthroscopy, were established as synovial explant cultures ex vivo or snap frozen for immunohistology. Mononuclear cell cultures were isolated from peripheral blood and synovial fluid of RA patients. Cultures were incubated with the TLR1\\/2 ligand, Pam3CSK4 (200 ng, 1 and 10 μg\\/ml), an anti-TLR2 antibody (OPN301, 1 μg\\/ml) or an immunoglobulin G (IgG) (1 μg\\/ml) matched control. The comparative effect of OPN301 and adalimumab (anti-tumour necrosis factor alpha) on spontaneous release of proinflammatory cytokines from RA synovial explants was determined using quantitative cytokine MSD multiplex assays or ELISA. OPN301 penetration into RA synovial tissue explants cultures was assessed by immunohistology. Results Pam3CSK4 significantly upregulated interleukin (IL)-6 and IL-8 in RA peripheral blood mononuclear cells (PBMCs), RA synovial fluid mononuclear cells (SFMCs) and RA synovial explant cultures (P < 0.05). OPN301 significantly decreased Pam3CSK4-induced cytokine production of tumour necrosis factor alpha (TNF-α), IL-1β, IL-6, interferon (IFN)-γ and IL-8 compared to IgG control in RA PBMCs and SFMCs cultures (all P < 0.05). OPN301 penetration of RA synovial tissue cultures was detected in the lining layer and perivascular regions. OPN301 significantly decreased spontaneous cytokine production of TNF-α, IL-1β, IFN-γ and IL-8 from RA synovial tissue explant cultures (all P < 0.05). Importantly, the inhibitory effect of OPN on spontaneous cytokine secretion was comparable to inhibition by anti-TNFα monoclonal antibody adalimumab. Conclusions These findings further support targeting TLR2 as a potential therapeutic agent for the treatment of RA.

  10. Consumption of energy and release of entropy into the biosphere

    International Nuclear Information System (INIS)

    Deutscher, G.

    2014-01-01

    The short-term threat on humanity is not the shortage of energy but rather the contamination of the environment. The concept of entropy is useful to assess the impact of humane activities on the environment. During most of earth history the increase of entropy was more than compensated by the energy brought by the sun. Today the intensive use of fossil fuels has reversed the trend: the biosphere entropy increases as CO 2 piles up in the atmosphere. The release of entropy is linked to the amount of energy we consume and to the efficiency of the process we use to produce it. Nuclear power plants release entropy as low-temperature heat but this amount of entropy is far less than the entropy released by fossil-fuel power plants under the form of CO 2 . (A.C.)

  11. Temperature effect on carbachol-induced depression of spontaneous quantal transmitter release in frog neuromuscular junction

    Czech Academy of Sciences Publication Activity Database

    Strunsky, E. G.; Borisover, M. D.; Nikolsky, E. E.; Vyskočil, František

    2001-01-01

    Roč. 26, 8-9 (2001), s. 891-897 ISSN 0364-3190 R&D Projects: GA AV ČR IAA7011902; GA MŠk OK 267 Grant - others:RFBR(RU) 99-04-48286; EU(XX) Nesting Institutional research plan: CEZ:AV0Z5011922 Keywords : carbachol * temperature * acetylcholine release Subject RIV: ED - Physiology Impact factor: 1.638, year: 2001

  12. Determination of kinetic energy release from metastable peak widths

    DEFF Research Database (Denmark)

    Petersen, Allan Christian; Sølling, Theis Ivan

    2017-01-01

    The kinetic energy that is released upon bond rupture is often represented as T1/2. A value that is derived from the FWHM of a fragment peak by the use of two different conversion formulas. The choice of formula depends on whether the peak is recorded by scanning a magnetic sector or an electrost......The kinetic energy that is released upon bond rupture is often represented as T1/2. A value that is derived from the FWHM of a fragment peak by the use of two different conversion formulas. The choice of formula depends on whether the peak is recorded by scanning a magnetic sector...

  13. Computer algorithms for automated detection and analysis of local Ca2+ releases in spontaneously beating cardiac pacemaker cells.

    Directory of Open Access Journals (Sweden)

    Alexander V Maltsev

    Full Text Available Local Ca2+ Releases (LCRs are crucial events involved in cardiac pacemaker cell function. However, specific algorithms for automatic LCR detection and analysis have not been developed in live, spontaneously beating pacemaker cells. In the present study we measured LCRs using a high-speed 2D-camera in spontaneously contracting sinoatrial (SA node cells isolated from rabbit and guinea pig and developed a new algorithm capable of detecting and analyzing the LCRs spatially in two-dimensions, and in time. Our algorithm tracks points along the midline of the contracting cell. It uses these points as a coordinate system for affine transform, producing a transformed image series where the cell does not contract. Action potential-induced Ca2+ transients and LCRs were thereafter isolated from recording noise by applying a series of spatial filters. The LCR birth and death events were detected by a differential (frame-to-frame sensitivity algorithm applied to each pixel (cell location. An LCR was detected when its signal changes sufficiently quickly within a sufficiently large area. The LCR is considered to have died when its amplitude decays substantially, or when it merges into the rising whole cell Ca2+ transient. Ultimately, our algorithm provides major LCR parameters such as period, signal mass, duration, and propagation path area. As the LCRs propagate within live cells, the algorithm identifies splitting and merging behaviors, indicating the importance of locally propagating Ca2+-induced-Ca2+-release for the fate of LCRs and for generating a powerful ensemble Ca2+ signal. Thus, our new computer algorithms eliminate motion artifacts and detect 2D local spatiotemporal events from recording noise and global signals. While the algorithms were developed to detect LCRs in sinoatrial nodal cells, they have the potential to be used in other applications in biophysics and cell physiology, for example, to detect Ca2+ wavelets (abortive waves, sparks and

  14. Postulated weather modification effects of large energy releases

    Energy Technology Data Exchange (ETDEWEB)

    Ramsdell, J.V.; Scott, B.C.; Orgill, M.M.; Renne, D.S.; Hubbard, J.E.; McGinnis, K.A.

    1977-02-01

    Postulated impacts of large energy releases were examined in the light of existing technical information. The magnitudes of direct atmospheric modifications were estimated, and the ecological and economic implications of the modifications were explored. Energy releases from energy centers (10 to 40 power plants at a single site) and individual power plant clusters (1 to 4 power plants) were considered. In the atmosphere the energy will exist initially as increased temperature (sensible heat), moisture (latent heat), and air motion (kinetic energy). Addition of energy could result in increased cloudiness and fog, and changed precipitation patterns. A framework for economic analysis of the impacts of the postulated atmospheric modifications was established on the basis of costs and benefits. Willingness-to-pay was selected as the appropriate measure for valuing each impact. The primary and secondary atmospheric modifications may affect recreation, transportation, and aesthetics as well as agriculture and forestry. Economic values can be placed on some of the effects. However, the willingness of people to pay to gain benefits and avoid damages in many cases can only be determined through extensive surveys. The economic consequences of a given energy release would be highly site specific.

  15. Postulated weather modification effects of large energy releases

    International Nuclear Information System (INIS)

    Ramsdell, J.V.; Scott, B.C.; Orgill, M.M.; Renne, D.S.; Hubbard, J.E.; McGinnis, K.A.

    1977-02-01

    Postulated impacts of large energy releases were examined in the light of existing technical information. The magnitudes of direct atmospheric modifications were estimated, and the ecological and economic implications of the modifications were explored. Energy releases from energy centers (10 to 40 power plants at a single site) and individual power plant clusters (1 to 4 power plants) were considered. In the atmosphere the energy will exist initially as increased temperature (sensible heat), moisture (latent heat), and air motion (kinetic energy). Addition of energy could result in increased cloudiness and fog, and changed precipitation patterns. A framework for economic analysis of the impacts of the postulated atmospheric modifications was established on the basis of costs and benefits. Willingness-to-pay was selected as the appropriate measure for valuing each impact. The primary and secondary atmospheric modifications may affect recreation, transportation, and aesthetics as well as agriculture and forestry. Economic values can be placed on some of the effects. However, the willingness of people to pay to gain benefits and avoid damages in many cases can only be determined through extensive surveys. The economic consequences of a given energy release would be highly site specific

  16. Effect of crack-microcracks interaction on energy release rates

    Science.gov (United States)

    Chudnovsky, A.; Wu, Shaofu

    1990-01-01

    The energy release rates associated with the main crack advancing into its surrounding damage zone, and the damage zone translation relative to the main crack, as well as the energy of interaction between the crack and the damage zone are analyzed. The displacement and stress fields for this crack-damage interaction problem are reconstructed by employing a semi-empirical stress analysis which involves experimental evaluation of the average microcrack density in the damage zone.

  17. β- and α2-Adrenoceptor Control of Vascular Tension and Catecholamine Release in Female Normotensive and Spontaneously Hypertensive Rats.

    Science.gov (United States)

    Berg, Torill

    2017-01-01

    As in humans, young, female, spontaneously hypertensive rats (SHR) have a lower blood pressure than male SHR. In male, normotensive rats (WKY), α 2 - and β 1+2 -adrenoceptors (AR) reciprocally controlled catecholamine release and vascular smooth muscle tension. This interaction was malfunctioning in male SHR. The present study analyzed if a favorable shift in the α 2 /β 1+2 AR interaction may represent an antihypertensive protection in females. Female SHR (early hypertension, 12-14 weeks) and age-matched WKY were infused with tyramine (15 min) to stimulate norepinephrine (NE) release through the reuptake transporter, consequently preventing reuptake. Presynaptic control of vesicular release was therefore reflected as differences in overflow to plasma. The released NE increased total peripheral vascular resistance (TPR). The results showed that β 1>2 AR facilitated tyramine-stimulated NE release in both strains, also in the presence of α 2 AR-antagonist (L-659,066). βAR-antagonist (atenolol-β 1 , ICI-118551-β 2 , nadolol-β 1+2 ) had no effect on the increased secretion of epinephrine after L-659,066 in WKY, but β 1>2 AR-antagonist augmented the L-659,066-induced increase in the secretion of epinephrine in SHR. Nadolol increased the TPR response to tyramine with a greater effect in WKY than SHR, whereas β 1or2 -selective antagonists did not. One βAR-subtype may therefore substitute for the other. When both β 1+2 AR were blocked, α 2 AR-antagonist still reduced the TPR response in WKY but not SHR. Thus, α 2 /β 1+2 AR reciprocally controlled catecholamine release, with a particular negative β 1 AR-influence on α 2 AR-auto-inhibition of epinephrine secretion in SHR. Moreover, in these female rats, β 1/2 AR-independent α 2 AR-mediated vasoconstriction was seen in WKY but not SHR, but β 1/2 AR-mediated vasodilation downregulated adrenergic vasoconstriction, not only in WKY but also in SHR.

  18. Flare Ribbon Expansion and Energy Release Ayumi Asai , Takaaki ...

    Indian Academy of Sciences (India)

    Flare Ribbon Expansion and Energy Release. Ayumi Asai. 1,∗. , Takaaki Yokoyama. 2. , Masumi Shimojo. 1. ,. Satoshi Masuda. 3. & Kazunari Shibata. 4. 1Nobeyama Solar Radio Observatory, Minamisaku, Nagano, 384-1305, Japan. 2Department of Earth and Planetary Science, University of Tokyo, Hongo, Bunkyo, Tokyo,.

  19. Fracture patterns and the energy release rate of phosphorene.

    Science.gov (United States)

    Liu, Ning; Hong, Jiawang; Pidaparti, Ramana; Wang, Xianqiao

    2016-03-14

    Phosphorene, also known as monolayer black phosphorus, has been enjoying popularity in electronic devices due to its superior electrical properties. However, it's relatively low Young's modulus, low fracture strength and susceptibility to structural failure have limited its application in mechanical devices. Therefore, in order to design more mechanically reliable devices that utilize phosphorene, it is necessary to explore the fracture patterns and energy release rate of phosphorene. In this study, molecular dynamics simulations are performed to investigate phosphorene's fracture mechanism. The results indicate that fracture under uniaxial tension along the armchair direction is attributed to a break in the interlayer bond angles, while failure in the zigzag direction is triggered by the break in both intra-layer angles and bonds. Furthermore, we developed a modified Griffith criterion to analyze the energy release rate of phosphorene and its dependence on the strain rates and orientations of cracks. Simulation results indicate that phosphorene's energy release rate remains almost unchanged in the armchair direction while it fluctuates intensively in the zigzag direction. Additionally, the strain rate was found to play a negligible role in the energy release rate. The geometrical factor α in the Griffith's criterion is almost constant when the crack orientation is smaller than 45 degree, regardless of the crack orientation and loading direction. Overall, these findings provide helpful insights into the mechanical properties and failure behavior of phosphorene.

  20. Spontaneous and stimulated radiations of a classical moving charge from energy conservation

    Science.gov (United States)

    Artru, X.

    2017-07-01

    In classical electrodynamics the amplitude of the radiation by a charged particle in non-uniform motion is usually derived from the Liénard-Wiechert retarded potential. We show that it can be derived in a simpler way by supposing an initial radiation field which stimulates the emission and using energy conservation. We also compare the forces which brake (or accelerate) the particle in spontaneous and stimulated emissions (or absorption).

  1. Spontaneous emission and scattering in a two-atom system: Conservation of probability and energy

    International Nuclear Information System (INIS)

    Berman, P. R.

    2007-01-01

    An explicit calculation of conservation of probability and energy in a two-atom system is presented. One of the atoms is excited initially and undergoes spontaneous emission. The field radiated by this atom can be scattered by the second atom. It is seen that the Weisskopf-Wigner approximation must be applied using a specific prescription to guarantee conservation of probability and energy. Moreover, for consistency, it is necessary to take into account the rescattering by the source atom of radiation scattered by the second atom

  2. Obese but not lean adolescents spontaneously decrease energy intake after intensive exercise.

    Science.gov (United States)

    Thivel, David; Metz, Lore; Julien, Aucouturier; Morio, Béatrice; Duché, Pascale

    2014-01-17

    Acute intensive exercise has been shown to induce a decreased subsequent daily energy intake in obese adolescents without altering the subjective appetite feelings. It is however unclear whether or not those nutritional adaptations to acute exercise are affected by the adolescents' weight status. The aim of this study was to compare the energy intake and macronutrient preferences, appetite feeling and energy expenditure response to acute exercise between lean and obese adolescents. Ten obese and nine normal weight 12-15year old adolescents randomly completed a session with a 30minute cycling exercise at 75% VO2max and a sedentary session. During both sessions energy expenditure was assessed using Armband, ad libitum energy intake measured by weighing at both lunch and dinner time and appetite feelings assessed using visual analog scales. Daily, morning and afternoon energy expenditure were significantly higher in obese than in normal weight adolescents (padolescents. Lunch, dinner and total daily energy intake were significantly reduced after the exercise session in obese (p>0.05) but not in lean adolescents. No group or condition effects were observed on subjective appetite feelings. Post exercise spontaneous energy intake and energy expenditure are reduced in obese but not in normal weight adolescents, without appetite feeling changes. Acute exercise may have a greater impact on energy balance through the induced decreased energy intake in the absence of significant change in energy expenditure in obese youth. © 2013 Elsevier Inc. All rights reserved.

  3. Spontaneous Fission and alpha -Decay Half-Lives of Superheavy Nuclei in Different Macroscopic Energy Models

    CERN Document Server

    Lojewski, Z; Pomorski, K

    2003-01-01

    Spontaneous fission half-lives (T sub s sub f) of the heaviest nuclei are calculated in the macroscopic-microscopic approach based on the deformed Woods-Saxon potential. Four different models of the macroscopic energy are examined and their influence on the results is discussed. The calculations of (T sub s sub f) are performed within WKB approximation. Multi-dimensional dynamical-programming method (MDP) is applied to minimize the action integral in a 3-dimensional space of deformation parameters describing the nuclear shape (beta sub 2 ,beta sub 4 ,beta sub 6).

  4. Development of mass and energy release analysis methodology

    International Nuclear Information System (INIS)

    Kim, Cheol Woo; Song, Jeung Hyo; Park, Seok Jeong; Kim, Tech Mo; Han, Kee Soo; Choi, Han Rim

    2009-01-01

    Recently, new approaches to the accident analysis using the realistic evaluation have been attempted. These new approaches provide more margins to the plant safety, design, operation and maintenance. KREM (KEPRI Realistic Evaluation Methodology) for a large break loss-of-coolant accident (LOCA) is performed using RELAP5/MOD3 computer code including realistic evaluation models. KOPEC has developed KIMERA (KOPEC Improved Mass and Energy Release Analysis methodology) based on the realistic evaluation to improve the analysis method for the mass and energy (M/E) release and to obtain the adequate margin. KIMERA uses a simplified single code system unlike conventional M/E release analysis methodologies. This simple code system reduces the computing efforts especially for LOCA analysis. The computer code systems of this methodology are RELAP5K/CONTEMPT4 (or RELAP5-ME) like KREM methodology which couples RELAP5/MOD3.1/K and CONTEMPT4/MOD5. The new methodology, KIMERA based on the same engine as KREM, adopted conservative approaches for the M/E release such as break spillage model, multiplier on heat transfer coefficient (HTC), and long-term cooling model. KIMERA is developed based on a LOCA and applied to a main steam line break (MSLB) and approved by Korea Government. KIMERA has an ability of one-through calculation of the various transient stages of LOCAs in a single code system and calculate the M/E release analysis during the long term cooling period with the containment pressure and temperature (P/T) response. The containment P/T analysis results are compared with those of the Ulchin Nuclear Power Plant Units 3 and 4 (UCN 3 and 4) FSAR which is the OPR1000 (Optimized Power Reactor 1000) type nuclear power plant. The results of a large break LOCA and an MSLB are similar to those of FSAR for UCN 3 and 4. However, the containment pressure during the post-blowdown period of a large break LOCA has much lower second peak than the first peak. The resultant containment peak

  5. Tunneling and reflection in unimolecular reaction kinetic energy release distributions

    Science.gov (United States)

    Hansen, K.

    2018-02-01

    The kinetic energy release distributions in unimolecular reactions is calculated with detailed balance theory, taking into account the tunneling and the reflection coefficient in three different types of transition states; (i) a saddle point corresponding to a standard RRKM-type theory, (ii) an attachment Langevin cross section, and (iii) an absorbing sphere potential at short range, without long range interactions. Corrections are significant in the one dimensional saddle point states. Very light and lightly bound absorbing systems will show measurable effects in decays from the absorbing sphere, whereas the Langevin cross section is essentially unchanged.

  6. What if energy decoupling of emerging economies were not so spontaneous? an illustrative example on India

    International Nuclear Information System (INIS)

    Mathy, S.; Guivarch, C.

    2009-02-01

    Reference GHG emissions scenarios are critical for estimates of the costs of stabilization and for climate policy recommendations. But recently, existing reference scenarios, notably the SRES, have been the target of criticisms that question their relevance in the light of current emissions trends, dispute the suitability, for developing countries, of the modeling methodologies used and suggest they convey too optimistic views on spontaneous energy decoupling of emerging countries economies. This article focuses on an illustrative example on India. It proposes an alternative reference scenario built with a modeling framework representing as realistically as possible the processes driving energy intensity and carbon intensity changes, in particular accounting for the interactions between energy systems and economic constraints and capturing the sub-optimalities of the energy sector. The mechanisms leading to moderate energy decoupling in this alternative scenario are analysed. From a methodological point of view, our results call for the improvement of the realism of modeling tools for scenarios elaboration. From a mitigation point of view, it appears that the challenge for climate policies to lift the barriers to the diffusion of energy efficiency improvement in India is considerable, but we identify a potential for synergies between development policies and climate policies. (authors)

  7. Multiplicity and correlated energy of gamma rays emitted in the spontaneous fission of Californium-252

    International Nuclear Information System (INIS)

    Brunson, G.S. Jr.

    1982-06-01

    An array of eight high-speed plastic scintillation detectors has been used to infer a mathematical model for the emission multipliciy of prompt gammas in the spontaneous fission of 252 Cf. Exceptional time resolution and coincidence capability permitted the separation of gammas from fast neutrons over a flight path of approximately 10 cm. About 20 different distribution models were tested. The average energy of the prompt gammas is inversely related to the number emitted; however, this inverse relationship is not strong and the total gamma energy does increase with increasing gamma number. An extension of the experiment incorporated a lithium-drifted germanium gamma spectrometer that resolved nearly 100 discrete gammas associated with fission. Of these gammas, some were preferentially associated with fission in which few gammas were emitted. Certain others were more frequent when many gammas were emitted. Results are presented

  8. Influence of LOD variations on seismic energy release

    Science.gov (United States)

    Riguzzi, F.; Krumm, F.; Wang, K.; Kiszely, M.; Varga, P.

    2009-04-01

    Tidal friction causes significant time variations of geodynamical parameters, among them geometrical flattening. The axial despinning of the Earth due to tidal friction through the change of flattening generates incremental meridional and azimuthal stresses. The stress pattern in an incompressible elastic upper mantle and crust is symmetric to the equator and has its inflection points at the critical latitude close to ±45°. Consequently the distribution of seismic energy released by strong, shallow focus earthquakes should have also sharp maxima at this latitude. To investigate the influence of length of day (LOD) variations on earthquake activity an earthquake catalogue of strongest seismic events (M>7.0) was completed for the period 1900-2007. It is shown with the use of this catalogue that for the studied time-interval the catalogue is complete and consists of the seismic events responsible for more than 90% of released seismic energy. Study of the catalogue for earthquakes M>7.0 shows that the seismic energy discharged by the strongest seismic events has significant maxima at ±45°, what renders probably that the seismic activity of our planet is influenced by an external component, i.e. by the tidal friction, which acts through the variation of the hydrostatic figure of the Earth caused by it. Distribution along the latitude of earthquake numbers and energies was investigated also for the case of global linear tectonic structures, such as mid ocean ridges and subduction zones. It can be shown that the number of the shallow focus shocks has a repartition along the latitude similar to the distribution of the linear tectonic structures. This means that the position of foci of seismic events is mainly controlled by the tectonic activity.

  9. Excitatory effect of the A2A adenosine receptor agonist CGS-21680 on spontaneous and K+-evoked acetylcholine release at the mouse neuromuscular junction.

    Science.gov (United States)

    Palma, A G; Muchnik, S; Losavio, A S

    2011-01-13

    The mechanism of action of the A2A adenosine receptor agonist 2-p-(2-carboxyethyl) phenethylamino-5'-N-ethylcarboxamidoadenosine hydrochloride (CGS-21680) in the facilitation of spontaneous (isotonic and hypertonic condition) and K+-evoked acetylcholine (ACh) release was investigated in the mouse diaphragm muscles. At isotonic condition, the CGS-21680-induced excitatory effect on miniature end-plate potential (MEPP) frequency was not modified in the presence of CdCl2 and in a medium free of Ca2+ (0Ca2+-EGTA), but it was abolished after buffering the rise of intracellular Ca2+ with 1,2-bis-(2-aminophenoxy)-ethane-N,N,N',N'-tetraacetic acid tetra(acetoxy-methyl) (BAPTA-AM) and when the Ca2+-ATPase inhibitor thapsigargin was used to deplete intracellular Ca2+ stores. CGS-21680 did not have a direct effect on the Ca2+-independent neurotransmitter-releasing machinery, since the modulatory effect on the hypertonic response was also occluded by BAPTA-AM and thapsigargin. CGS-21680 facilitation on K+-evoked ACh release was not altered by the P/Q-type voltage-dependent calcium channel (VDCC) blocker ω-Agatoxin IVA, but it was completely prevented by both, the L-type VDCC blocker nitrendipine (which is known to immobilize their gating charges), or thapsigargin, suggesting that the effects of CGS-21680 on L-type VDCC and thapsigargin-sensitive internal stores are associated. We found that the VDCC pore blocker Cd2+ (2 mM Ca2+ or 0Ca2+-EGTA) failed to affect the CGS-21680 effect in high K+ whereas nitrendipine in 0Ca2+-EGTA+Cd2+ occluded its action. The blockade of Ca2+ release from endoplasmic reticulum with ryanodine antagonized the facilitating effect of CGS-21680 in control and high K+ concentration. It is concluded that, at the mouse neuromuscular junction, activation of A2A receptors facilitates spontaneous and K+-evoked ACh release by an external Ca2+-independent mechanism but that involves mobilization of Ca2+ from internal stores: during spontaneous ACh release

  10. Free energy dissipation of the spontaneous gating of a single voltage-gated potassium channel

    Science.gov (United States)

    Wang, Jia-Zeng; Wang, Rui-Zhen

    2018-02-01

    Potassium channels mainly contribute to the resting potential and re-polarizations, with the potassium electrochemical gradient being maintained by the pump Na+/K+-ATPase. In this paper, we construct a stochastic model mimicking the kinetics of a potassium channel, which integrates temporal evolving of the membrane voltage and the spontaneous gating of the channel. Its stationary probability density functions (PDFs) are found to be singular at the boundaries, which result from the fact that the evolving rates of voltage are greater than the gating rates of the channel. We apply PDFs to calculate the power dissipations of the potassium current, the leakage, and the gating currents. On a physical perspective, the essential role of the system is the K+-battery charging the leakage (L-)battery. A part of power will inevitably be dissipated among the process. So, the efficiency of energy transference is calculated.

  11. Reaction initiation and chemical energy release in nitramines

    Science.gov (United States)

    Schweigert, Igor

    2017-06-01

    Available kinetic data for condensed-phase reactions responsible for reaction initiation and chemical energy release in reacting explosives is extremely limited, even for widely used classes of molecular explosives such as nitramines. Transient temperatures and stresses generated in different initiation scenarios can vary by several orders of magnitude making it difficult to interpret kinetic data from initiation measurements. In this presentation, I will describe an ongoing theoretical effort aimed at identifying the dominant reaction mechanisms under different thermodynamic conditions, estimating the corresponding rate constants, and developing reduced-order rate models suitable for mesoscale simulations of detonation initiation. This work was supported by the Office of Naval Research, both directly and through the U.S. Naval Research Laboratory.

  12. Modelling the influence of short term depression in vesicle release and stochastic calcium channel gating on auditory nerve spontaneous firing statistics

    Directory of Open Access Journals (Sweden)

    Bahar eMoezzi

    2014-12-01

    Full Text Available We propose several modifications to an existing computational model of stochastic vesicle release in inner hair cell ribbon synapses, with the aim of producing simulated auditory nerve fibre spiking data that more closely matches empirical data. Specifically, we studied the inter-spike-interval (ISI distribution, and long and short term ISI correlations in spontaneous spiking in post-synaptic auditory nerve fibres. We introduced short term plasticity to the pre-synaptic release probability, in a manner analogous to standard stochastic models of cortical short term synaptic depression. This modification resulted in a similar distribution of vesicle release intervals to that estimated from empirical data. We also introduced a biophysical stochastic model of calcium channel opening and closing, but showed that this model is insufficient for generating a match with empirically observed spike correlations. However, by combining a phenomenological model of channel noise and our short term depression model, we generated short and long term correlations in auditory nerve spontaneous activity that qualitatively match empirical data.

  13. Carbon Dioxide Flush of an Integrated Minimized Perfusion Circuit Prior to Priming Prevents Spontaneous Air Release Into the Arterial Line During Clinical Use.

    Science.gov (United States)

    Stehouwer, Marco C; de Vroege, Roel; Hoohenkerk, Gerard J F; Hofman, Frederik N; Kelder, Johannes C; Buchner, Bas; de Mol, Bastian A; Bruins, Peter

    2017-11-01

    Recently, an oxygenator with an integrated centrifugal blood pump (IP) was designed to minimize priming volume and to reduce blood foreign surface contact even further. The use of this oxygenator with or without integrated arterial filter was compared with a conventional oxygenator and nonintegrated centrifugal pump. To compare the air removal characteristics 60 patients undergoing coronary artery bypass grafting were alternately assigned into one of three groups to be perfused with a minimized extracorporeal circuit either with the conventional oxygenator, the oxygenator with IP, or the oxygenator with IP plus integrated arterial filter (IAF). Air entering and leaving the three devices was measured accurately with a bubble counter during cardiopulmonary bypass. No significant differences between all groups were detected, considering air entering the devices. Our major finding was that in both integrated devices groups incidental spontaneous release of air into the arterial line in approximately 40% of the patients was observed. Here, detectable bolus air (>500 µm) was shown in the arterial line, whereas in the minimal extracorporeal circulation circuit (MECC) group this phenomenon was not present. We decided to conduct an amendment of the initial design with METC-approval. Ten patients were assigned to be perfused with an oxygenator with IP and IAF. Importantly, the integrated perfusion systems used in these patients were flushed with carbon dioxide (CO 2 ) prior to priming of the systems. In the group with CO 2 flush no spontaneous air release was observed in all cases and this was significantly different from the initial study with the group with the integrated device and IAF. This suggests that air spilling may be caused by residual air in the integrated device. In conclusion, integration of a blood pump may cause spontaneous release of large air bubbles (>500 µm) into the arterial line, despite the presence of an integrated arterial filter. CO 2 flushing of

  14. Provence-Alpes-Cote d'Azur regional energy observatory - Assessment 2002, Assessment 2003, Assessment 2004, Assessment 2005, Release 2007, Release 2008, Release 2009, Release 2010, Release 2011, Assessment 2011/Release 2012, Release 2013; Provence-Alpes-Cote d'Azur Energy, Climate and Air regional observatory - 2013-Release 2014, 2014-Release 2015, 2015-Release 2016, 2016-Release 2017

    International Nuclear Information System (INIS)

    Chabannes, Carole; Pamelle, Yohann; Le Maitre, Stephanie; Lyant, Valentin; Gondolo, Philippe; Belhcen, Ludovic; Laverdiere, Folco; Moynet, Matthieu; Luneau, Gaelle; Borel, F.

    2002-01-01

    Illustrated by graphs, maps and tables, this set of documents provides and comments (sometimes in a rather developed way for some issues, depending on the publication year), for years between 2002 and 2016, information and data related to regional energy consumption (in terms of consuming sector and in terms of energy source), energy production (from different sources: wood, coal, hydraulic, wastes, solar photovoltaic and thermal), greenhouse gas emissions, electric power production and demand (with a focus on some specific sectors). Issues addressed in these documents evolve in time as the concept of renewable energy emerged, as important consuming sector are identified (transports, buildings, for example), and also as the issue of energy saving is more precisely studied. Activities of the regional energy observatory are also mentioned. From 2013, issues related to climate and air quality are also addressed at the same level as power production, solar photovoltaic and thermal energy, wind energy, wood-energy, energy savings, energy prices, studies performed by the observatory, and issues related to transports

  15. Volatiles and energy released by Puracé volcano

    Science.gov (United States)

    Maldonado, Luisa Fernanda Meza; Inguaggiato, Salvatore; Jaramillo, Marco Tulio; Valencia, Gustavo Garzón; Mazot, Agnes

    2017-12-01

    Total CO2 output of Puracé volcano (Colombia) was estimated on the basis of fluids discharged by fumaroles, soil gases, and dissolved carbon species in the aquifer. The soil CO2 emission was computed from a field survey of 512 points of CO2 soil flux measurements at the main degassing areas of Puracé volcano. The CO2 flux from Puracé's plume was estimated using an indirect method, that used the SO2 plume flux and CO2/SO2 ratio of the main high temperature fumarole. The total output of CO2 was estimated at ≅ 1500 t/day. The main contribution of CO2 comes from the plume (summit degassing) and from soil degassing that emit 673 and 812 t/day, respectively. The contributions of summit and soil degassing areas are comparable, indicating an intermediate degassing style partitioned between closed and open conduit systems. The estimated water vapor discharge (as derived from the chemical composition of the fumaroles, the H2O/CO2 ratio, and the SO2 plume flux) allowed calculation of the total thermal energy (fumarolic, soil degassing, and aquifer) released from the Puracé volcanic system. This was 360 MW.

  16. Prediction of Peak Hydrogen Concentrations for Deep Sludge Retrieval in Tanks AN-101 and AN-106 from Historical Data of Spontaneous Gas Release Events

    Energy Technology Data Exchange (ETDEWEB)

    Wells, Beric E.; Cooley, Scott K.; Meacham, Joseph E.

    2013-10-21

    Radioactive and chemical wastes from nuclear fuel processing are stored in large underground storage tanks at the Hanford Site. The Tank Operations Contractor is continuing a program of moving solid wastes from single-shell tanks (SSTs) to double-shell tanks (DSTs) and preparing for waste feed delivery (WFD). A new mechanism for a large spontaneous gas release event (GRE) in deep sludge sediments has been postulated. The creation of this potential new GRE hazard, deep sludge gas release events (DSGREs), is the retrieval of sludge waste into a single DST that results in a sediment depth greater than operating experience has demonstrated is safe. The Tank Operations Contractor program of moving solid wastes from SSTs to DSTs and preparing for WFD is being negatively impacted by this sediment depth limit.

  17. The spontaneous release of prostaglandins into the cerebral ventricles of the dog and the effect of external factors on this release

    Science.gov (United States)

    Holmes, S. W.

    1970-01-01

    1. Prostaglandins E1, E2, F1α and F2α have been identified in perfusates of the cerebral ventricles of anaesthetized dogs. 2. Infusions of serotonin into the lateral ventricle caused a four-fold increase in the release of prostaglandins E into the ventricles and this increase was dissociated from the hyperthermic action. Intraventricular infusions of adrenaline and noradrenaline had no effect on the level of prostaglandin release. 3. Neither electrical stimulation of a hind foot pad nor the intraperitoneal administration of chlorpromazine, amphetamine, tranylcypromine or imipramine had any consistent effect on the amounts of prostaglandins released into the cerebrospinal fluid. 4. When prostaglandin E1 was added to the fluid perfusing the ventricular system, respiratory changes were observed but almost all the added prostaglandin was recovered from the perfusate leaving the cisterna. PMID:5441786

  18. Optically-controlled long-term storage and release of thermal energy in phase-change materials.

    Science.gov (United States)

    Han, Grace G D; Li, Huashan; Grossman, Jeffrey C

    2017-11-13

    Thermal energy storage offers enormous potential for a wide range of energy technologies. Phase-change materials offer state-of-the-art thermal storage due to high latent heat. However, spontaneous heat loss from thermally charged phase-change materials to cooler surroundings occurs due to the absence of a significant energy barrier for the liquid-solid transition. This prevents control over the thermal storage, and developing effective methods to address this problem has remained an elusive goal. Herein, we report a combination of photo-switching dopants and organic phase-change materials as a way to introduce an activation energy barrier for phase-change materials solidification and to conserve thermal energy in the materials, allowing them to be triggered optically to release their stored latent heat. This approach enables the retention of thermal energy (about 200 J g -1 ) in the materials for at least 10 h at temperatures lower than the original crystallization point, unlocking opportunities for portable thermal energy storage systems.

  19. The Midi-Pyrenees regional energy observatory - Release 2005

    International Nuclear Information System (INIS)

    Malvy, Martin; Daubigny, Jean; Fraysse, Jean-Marie; Dedieu-Casties, Francoise; RIEY, Benedicte

    2005-01-01

    Illustrated with maps and graphs, this publication proposes a synthetic and brief energy assessment for the Midi-Pyrenees region. It briefly presents the regional energy situation in terms of final energy consumption between 1990 and 2003, of primary energy production during the same period, of inventories of greenhouse gas emissions, and of CO 2 emissions by the energy sector. It also proposes an overview of the situation, evolution and production of various energy sources: hydroelectricity, wood, wind, solar photovoltaic, solar and thermal energy, co-generation, and other types of energy valorisation modes (biogas, combustion). It proposes a focus on two important sectors, transports and housing

  20. Reaction pathways and free energy profiles for spontaneous hydrolysis of urea and tetramethylurea: Unexpected substituent effects

    Science.gov (United States)

    Yao, Min; Tu, Wenlong; Chen, Xi; Zhan, Chang-Guo

    2013-01-01

    It has been difficult to directly measure the spontaneous hydrolysis rate of urea and, thus, 1,1,3,3-tetramethylurea (Me4U) was used as a model to determine the “experimental” rate constant for urea hydrolysis. The use of Me4U was based on an assumption that the rate of urea hydrolysis should be 2.8 times that of Me4U hydrolysis because the rate of acetamide hydrolysis is 2.8 times that of N,N-dimethyl-acetamide hydrolysis. The present first-principles electronic-structure calculations on the competing non-enzymatic hydrolysis pathways have demonstrated that the dominant pathway is the neutral hydrolysis via the CN addition for both urea (when pHhydrolysis of amides where alkaline hydrolysis is dominant. Based on the computational data, the substituent shift of free energy barrier calculated for the neutral hydrolysis is remarkably different from that for the alkaline hydrolysis, and the rate constant for the urea hydrolysis should be ~1.3×109-fold lower than that (4.2×10−12 s−1) measured for the Me4U hydrolysis. As a result, the rate enhancement and catalytic proficiency of urease should be 1.2×1025 and 3×1027 M−1, respectively, suggesting that urease surpasses proteases and all other enzymes in its power to enhance the rate of reaction. All of the computational results are consistent with available experimental data for Me4U, suggesting that the computational prediction for urea is reliable. PMID:24097048

  1. Chronic cigarette smoking enhances spontaneous release of tumour necrosis factor-α from alveolar macrophages of rats

    Directory of Open Access Journals (Sweden)

    G. P. Pessina

    1993-01-01

    Full Text Available Some biological effects of chronic cigarette smoking (two cigarettes for 2 h, daily for 4 months in rats were evaluated. During the smoking period, body weight of smoker rats was always significantly lower than that of control rats. Immediately after the last smoking session the carboxyhaemoglobin concentration in the blood was about 8.5% and the polymorphonuclear cells in the bronchoalveolar fluid increased significantly. At the same time, enzymatic analyses on the supernatants of bronchoalveolar fluid revealed a significant increase of β-glucuronidase in the smoker group. Alveolar macrophages, collected 0, 8 and 24 h after the last smoking session, significantly increased the generation of superoxide anion and, after incubation for 24 h at 37° C in a humidified atmosphere, released significantly high amounts of TNF-α. When challenged with lipopolysaccharide, alveolar macrophages of smoker rats released much more TNF-α but, in such a case, TNF-α release was about one half of that observed in the control group. Peritoneal macrophages of both control and smoker rats were unable either to generate high levels of superoxide anion or to release significant amounts of TNF-α. The results clearly demonstrated the activated state of alveolar macrophages and the resting state of peritoneal macrophages.

  2. Climate, air and energy - Release 2015 - Key figures

    International Nuclear Information System (INIS)

    2016-05-01

    After an indication of some remarkable key figures (general data, data about office building, housing, industries, renewable energies, wastes, transports, agriculture and forests, and households, indication of some French and European objectives for 2020 and 2030), and a table containing indications of some international official texts (Kyoto protocol and its amendment, European directives) and of their content and scope (bio-fuels in transports, energy efficiency, buildings, labelling and eco-design, transports, renewable energies, energy and climate, greenhouse gas emissions and adaptation, air quality, wastes), and national texts (laws, plans) regarding the same issues, this publication presents figures and data under the form of graphs and tables to illustrate their evolution. They are general data on energy consumptions and intensities (data per sector and per country in Europe), markets and jobs related to renewable energies, certificates of energy saving, greenhouse gas emissions and climate change, regional data for France. The other chapters present large sets of graphs and tables of relevant data concerning housing buildings, office buildings, transports, industries, agriculture and forests, renewable energies and heat networks, wastes, and households. Generally, these data are presented in terms of evolution since the 1970's or the 1990's. They propose a detailed analytical point of view of the various energy and energy-related issues in these different sectors and fields

  3. Mixed quantum-classical electrodynamics: Understanding spontaneous decay and zero-point energy

    Science.gov (United States)

    Li, Tao E.; Nitzan, Abraham; Sukharev, Maxim; Martinez, Todd; Chen, Hsing-Ta; Subotnik, Joseph E.

    2018-03-01

    The dynamics of an electronic two-level system coupled to an electromagnetic field are simulated explicitly for one- and three-dimensional systems through semiclassical propagation of the Maxwell-Liouville equations. We consider three flavors of mixed quantum-classical dynamics: (i) the classical path approximation (CPA), (ii) Ehrenfest dynamics, and (iii) symmetrical quasiclassical (SQC) dynamics. Our findings are as follows: (i) The CPA fails to recover a consistent description of spontaneous emission, (ii) a consistent "spontaneous" emission can be obtained from Ehrenfest dynamics, provided that one starts in an electronic superposition state, and (iii) spontaneous emission is always obtained using SQC dynamics. Using the SQC and Ehrenfest frameworks, we further calculate the dynamics following an incoming pulse, but here we find very different responses: SQC and Ehrenfest dynamics deviate sometimes strongly in the calculated rate of decay of the transient excited state. Nevertheless, our work confirms the earlier observations by Miller [J. Chem. Phys. 69, 2188 (1978), 10.1063/1.436793] that Ehrenfest dynamics can effectively describe some aspects of spontaneous emission and highlights interesting possibilities for studying light-matter interactions with semiclassical mechanics.

  4. Software energy profiling: comparing releases of a software product

    NARCIS (Netherlands)

    Jagroep, Erik; van der Werf, J.M.E.M.; Brinkkemper, S.; Procaccianti, Guiseppe; Lago, Patricia; Blom, Leen; van Vliet, Rob

    2016-01-01

    In the quest for energy efficiency of Information and Communication Technology, so far research has mostly focused on the role of hardware. However, as hardware technology becomes more sophisticated, the role of software becomes crucial. Recently, the impact of software on energy consumption has

  5. Software Energy Profiling: Comparing Releases of a Software Product

    NARCIS (Netherlands)

    Jagroep, E.A.; van der Werf, J.M.E.M.; Procaccianti, G.; Lago, P.; Brinkkemper, Sjaak; Blom, L.; van Vliet, Rob; Dillon, Laura; Visser, Willem; Williams, Laurie

    2016-01-01

    In the quest for energy efficiency of Information and Communication Technology, so far research has mostly focused on the role of hardware. However, as hardware technology becomes more sophisticated, the role of software becomes crucial. Recently, the impact of software on energy consumption has

  6. Mechanical efficiency of the energy release during a steam explosion

    International Nuclear Information System (INIS)

    Krieg, R.

    1997-01-01

    The mechanical processes during the expansion phase of a steam explosion with intimately fragmented liquid particles is investigated based on elementary principles and analytical solutions. During a short load pulse, the different densities of the water and the melted particles lead to different velocities. After the load pulse, viscosity effects lead to a slow down of the higher velocities and to a corresponding reconversion of the kinetic energy of the mixture into thermal energy. It is shown that both effects are proportional to each other. The ratio between the residual and the applied mechanical energy is defined as the mechanical efficiency of the steam explosion. Using data typical for a steam explosion in a pressurized water reactor, mechanical efficiencies of <50% are estimated. Considering that the thermodynamic efficiencies are quite limited, the very low conversion rates from thermal energy into mechanical energy observed during steam explosion experiments can be more easily understood

  7. An atomistic methodology of energy release rate for graphene at nanoscale

    International Nuclear Information System (INIS)

    Zhang, Zhen; Lee, James D.; Wang, Xianqiao

    2014-01-01

    Graphene is a single layer of carbon atoms packed into a honeycomb architecture, serving as a fundamental building block for electric devices. Understanding the fracture mechanism of graphene under various conditions is crucial for tailoring the electrical and mechanical properties of graphene-based devices at atomic scale. Although most of the fracture mechanics concepts, such as stress intensity factors, are not applicable in molecular dynamics simulation, energy release rate still remains to be a feasible and crucial physical quantity to characterize the fracture mechanical property of materials at nanoscale. This work introduces an atomistic simulation methodology, based on the energy release rate, as a tool to unveil the fracture mechanism of graphene at nanoscale. This methodology can be easily extended to any atomistic material system. We have investigated both opening mode and mixed mode at different temperatures. Simulation results show that the critical energy release rate of graphene is independent of initial crack length at low temperature. Graphene with inclined pre-crack possesses higher fracture strength and fracture deformation but smaller critical energy release rate compared with the graphene with vertical pre-crack. Owing to its anisotropy, graphene with armchair chirality always has greater critical energy release rate than graphene with zigzag chirality. The increase of temperature leads to the reduction of fracture strength, fracture deformation, and the critical energy release rate of graphene. Also, higher temperature brings higher randomness of energy release rate of graphene under a variety of predefined crack lengths. The energy release rate is independent of the strain rate as long as the strain rate is small enough

  8. Costs of renewable energies in France. Release 2016

    International Nuclear Information System (INIS)

    Guillerminet, Marie-Laure; Marchal, David; Gerson, Raphael; Berrou, Yolene; Grouzard, Patrice

    2016-12-01

    For each renewable energy, this study reports the assessment of the range of the theoretical variation of costs with respect to the most important parameters of the concerned sector. Low range notably corresponds to particularly favourable financing modalities added to a good field quality and to low investment costs. At the opposite, the capital cost is particularly high for high ranges. Thus, after a presentation of the adopted methodology, the report addresses the costs of electric power generation for on-shore wind energy, offshore wind energy, sea hydraulics, photovoltaic, thermodynamic solar, and geothermal energy. The next part addresses heat production costs in the case of individuals (biomass, individual thermal solar, individual heat pumps) and of collective housing and office and industrial buildings (collective biomass with or without heat network, industrial biomass, thermal solar in collective housing of in network, collective geothermal heat pumps, deep geothermal energy). The fourth chapter addresses the cost of power and heat production by co-generation (biomass co-generation, methanization). Appendices provide computation hypotheses, and reference data

  9. National Energy Board releases 1994 annual report. Part 2

    International Nuclear Information System (INIS)

    1995-01-01

    The 1994 Annual Report of the National Energy Board is published in two parts, the first being in the April 1,1995 issue and the second part in this April 15 issue. The 1994 Annual Report of the National Energy Board, has been tabled in Parliament. The report reviews the Board's major regulatory and advisory activities, including decisions taken on natural gas, oil and electricity exports, pipeline construction, toils and tariffs and certain frontier activities. It also provides an overview of the energy situation in Canada. In its overview, the Board shows that Canadian exports of natural gas, petroleum and electricity increased by 6.9% from 1993 to 1994. Natural gas exports were up 13%, crude oil 7% and electricity 52%. The value of these exports is estimated to be $17.0 billion in 1994 compared with $15.4 billion in 1993. The Canadian energy sector play an important role in the Canadian economy. In 1994, the Canadian energy sector represented about seven percent (approximately $20 billion) of total Canadian exports. 9 tabs

  10. Dependence of anaphylactic histamine release from rat mast cells on cellular energy metabolism

    DEFF Research Database (Denmark)

    Johansen, Torben

    1981-01-01

    The relation between anaphylactic histamine release and the adenosine triphosphate (ATP) content of the mast cells was studied. The cells were incubated with glycolytic (2-deoxyglucose) and respiratory inhibitors (antimycin A and oligomycin) in order to decrease the ATP content of the cells prior...... pretreated with 2-deoxyglucose. The release of histamine from these cells was reduced when respiratory inhibitors were added to the cell suspension 5 to 20 sec after exposure of the cells to antigen. This may indicate that the secretory process requires energy, and it seems necessary that energy should...... be produced as the release of histamine takes place....

  11. Energy storage and release of prosthetic feet. Part 1: biomechanical analysis related to user benefits

    NARCIS (Netherlands)

    Postema, K.; Hermens, Hermanus J.; de Vries, J.; de Vries, J.; Koopman, Hubertus F.J.M.; Eisma, W.H.

    1997-01-01

    The energy storing and releasing behaviour of 2 energy storing feet (ESF) and 2 conventional prosthetic feet (CF) were compared (ESF: Otto Bock Dynamic Pro and Hanger Quantum; CF: Otto Bock Multi Axial and Otto Bock Lager). Ten trans-tibial amputees were selected. The study was designed as a

  12. Theoretical energy release of thermites, intermetallics, and combustible metals

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, S.H.; Grubelich, M.C.

    1998-06-01

    Thermite (metal oxide) mixtures, intermetallic reactants, and metal fuels have long been used in pyrotechnic applications. Advantages of these systems typically include high energy density, impact insensitivity, high combustion temperature, and a wide range of gas production. They generally exhibit high temperature stability, and possess insensitive ignition properties. In this paper, the authors review the applications, benefits, and characteristics of thermite mixtures, intermetallic reactants, and metal fuels. Calculated values for reactant density, heat of reaction (per unit mass and per unit volume), and reaction temperature (without and with consideration of phase changes and the variation of specific heat values) are tabulated. These data are ranked in several ways, according to density, heat of reaction, reaction temperature, and gas production.

  13. Translational Science: How experimental research has contributed to the understanding of spontaneous Physical Activity and Energy Homeostasis

    Directory of Open Access Journals (Sweden)

    Izabelle D Benfato

    2017-05-01

    Full Text Available Abstract Spontaneous physical activity (SPA consists of all daily living activities other than volitional exercise (e.g. sports and fitness-related activities. SPA is an important component of energy expenditure and may protect from overweight and obesity. Little is known about the biological regulation of SPA, but animal researchhas contributedsignificantly to expand our knowledge in this field. Studies in rodents have shown that SPA is influenced by nutrients and volitional exercise. High-fat diet seems to decrease SPA, which contributes to weigh gain. Volitional exercisemayalso reduce SPA, helping to explain the commonly reported low efficiency of exercise to cause weight loss, and highlighting the need to finda volume/intensity of exercise to maximize total daily energy expenditure. Animal studieshave also allowed for the identification of some brain areas and chemical mediatorsinvolved in SPA regulation. These discoveries could enable the development of new therapeutics aiming to enhance SPA.

  14. Comparative effects of pentobarbital on spontaneous and evoked transmitter release from inhibitory and excitatory nerve terminals in rat CA3 neurons.

    Science.gov (United States)

    Shin, Min-Chul; Wakita, Masahito; Iwata, Satomi; Nonaka, Kiku; Kotani, Naoki; Akaike, Norio

    2013-01-01

    Pentobarbital (PB) modulates GABA(A) receptor-mediated postsynaptic responses through various mechanisms, and can directly activate the channel at higher doses. These channels exist both pre- and postsynaptically, and on the soma outside the synapse. PB also inhibits voltage-dependent Na⁺ and Ca²⁺ channels to decrease excitatory synaptic transmission. Just how these different sites of action combine to contribute to the overall effects of PB on inhibitory and excitatory synaptic transmission is less clear. To compare these pre- and postsynaptic actions of PB, we used a 'synaptic bouton' preparation of isolated rat hippocampal CA3 pyramidal neurons where we could measure in single neurons the effects of PB on spontaneous and single bouton evoked GABAergic inhibitory and glutamatergic excitatory postsynaptic currents (sIPSCs, sEPSCs, eIPSCs and eEPSCs), respectively. Low (sedative) concentrations (3-10 μM) of PB increased the frequency and amplitude of sIPSCs and sEPSCs, and also presynaptically increased the amplitude of both eIPSCs and eEPSCs. There was no change in current kinetics at this low concentration. At higher concentrations (30-300 μM), PB decreased the frequency, and increased the amplitude of sIPSCs, and presynaptically decreased the amplitude of eIPSCs. The current decay phase of sIPSCs and eIPSCs was increased. An increase in both frequency and amplitude was seen for sEPSCs, while the eIPSCs was also decreased by a bicuculline-sensitive presynaptic effect. The results confirm the multiple sites of action of PB on inhibitory and excitatory transmission and demonstrate that the most sensitive site of action is on transmitter release, via effects on presynaptic GABA(A) receptors. At low concentrations, however, both glutamate and GABA release is similarly enhanced, making the final effects on neuronal excitability difficult to predict and dependent on the particular systems involved and/or on subtle differences in susceptibility amongst

  15. Intermittent Coronal Loop Oscillations by Random Energy Releases

    Science.gov (United States)

    Mendoza-Briceño, César A.; Erdélyi, Robert

    2006-09-01

    High-resolution observations by the SOHO and TRACE spacecraft have confirmed the existence of coronal loop oscillations and waves. In a recent work, Mendoza-Briceño et al. studied the heating response of coronal plasma to energy pulses randomly distributed in time and space along coronal loops. In this paper we focus on the oscillatory patterns and other features, such as cool gas blobs traveling along the loop, during the evolution of spatiotemporal randomly heated flux tubes in the corona. The nature of these oscillatory patterns is investigated using wavelet analysis. Periodic features, such as wave packets, with periods of 150-220, 500-600, and 800-1000 s are found. It is also found that the periods increase with the loop length and decrease with the length of the loop segments along which the pulses are injected. On the other hand, the randomly driven intermittent cool plasma blobs that propagate from one footpoint to the other are analyzed. Although plenty of coronal loop oscillations are detected by the cohort of the current high-resolution satellites, there are more controversial observational evidences about the predicted cold plasma blobs.

  16. Theoretical Energy Release of Thermites, Intermetallics, and Combustible Metals

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, S.H.; Grubelich, M.C.

    1999-05-14

    Thermite mixtures, intermetallic reactants, and metal fuels have long been used in pyrotechnic applications. Advantages of these systems typically include high energy density, high combustion temperature, and a wide range of gas production. They generally exhibit high temperature stability and possess insensitive ignition properties. For the specific applications of humanitarian demining and disposal of unexploded ordnance, these pyrotechnic formulations offer additional benefits. The combination of high thermal input with low brisance can be used to neutralize the energetic materials in mines and other ordnance without the "explosive" high-blast-pressure events that can cause extensive collateral damage to personnel, facilities, and the environment. In this paper, we review the applications, benefits, and characteristics of thermite mixtures, intermetallic reactants, and metal fuels. Calculated values for reactant density, heat of reaction (per unit mass and per unit volume), and reaction temperature (without and with consideration of phase changes and the variation of specific heat values) are tabulated. These data are ranked in several ways, according to density, heat of reaction, reaction temperature, and gas production.

  17. Meteorological Effects of Thermal Energy Releases (METER) Program. Annual progress report, October 1978-September 1979

    International Nuclear Information System (INIS)

    Patrinos, A.A.N.; Hoffman, H.W.

    1980-04-01

    The METER (Meteorological Effects of Thermal Energy Releases) Program was organized to develop and verify methods for predicting the maximum amount of energy that can be dissipated to the atmosphere (through cooling towers or cooling ponds) from proposed nuclear energy centers without affecting...the local and regional environment. The initial program scope (mathematical modeling, laboratory and field experimentation, and societal impact assessment) has now narrowed to emphasis on the acquisition of field data of substantial quality and extent

  18. Translational and extensional energy release rates (the J- and M-integrals) for a crack layer in thermoelasticity

    Science.gov (United States)

    Chudnovsky, A.; Gommerstadt, B.

    1985-01-01

    A number of papers have been presented on the evaluation of energy release rate for thermoelasticity and corresponding J integral. Two main approaches were developed to treat energy release rate in elasticity. The first is based on direct calculation of the potential energy rate with respect to crack length. The second makes use of Lagrangian formalism. The translational and expansional energy release rates in thermoelasticity are studied by employing the formalism of irreversible thermodynamics and the Crack Layer Approach.

  19. Energy release and transformation of shock-modified zirconia upon annealing to 1550 deg C

    Science.gov (United States)

    Hammetter, W. F.; Hellmann, J. R.; Graham, R. A.; Morosin, B.

    Shock modified powder samples were studied in DTA measurements to 1550 C to determine the influence of shock modification on energy release and on the monoclinic to tetragonal transformation. Energy release over that of control samples is observed to begin at appox. 200 C and continues to the onset of the transformation. The phase transformation temperature is at approx. 1170 C and is unaffected by shock loading pressure up to 16 GPa. Above that pressure, the transformation temperature is lowered as pressure increases. The decrease in temperature correlates with both the decrease in crystallite size and retention of the tetragonal phase indicated by X-ray diffraction.

  20. A methodology to study cyclic debond growth at constant mode-mixity and energy release rate

    DEFF Research Database (Denmark)

    Quispitupa, Amilcar; Berggreen, Christian; Carlsson, Leif A.

    2010-01-01

    It is well known that face/core debond crack propagation is governed by the critical energy release rate (fracture toughness) and mode-mixity at the crack tip. Thus, the current study focuses on the developing of a methodology to perform fatigue crack growth experiments of debonded sandwich...... structures under well controlled cyclic energy release rate and mode-mixity. The proposed methodology uses the mixed mode bending (MMB) sandwich specimen and MMB test rig. Crack length measurements are based on an analytically available compliance expression. Accurate fatigue crack growth measurements...

  1. Beat-to-Beat Variation in Periodicity of Local Calcium Releases Contributes to Intrinsic Variations of Spontaneous Cycle Length in Isolated Single Sinoatrial Node Cells.

    Directory of Open Access Journals (Sweden)

    Oliver Monfredi

    Full Text Available Spontaneous, submembrane local Ca(2+ releases (LCRs generated by the sarcoplasmic reticulum in sinoatrial nodal cells, the cells of the primary cardiac pacemaker, activate inward Na(+/Ca(2+-exchange current to accelerate the diastolic depolarization rate, and therefore to impact on cycle length. Since LCRs are generated by Ca(2+ release channel (i.e. ryanodine receptor openings, they exhibit a degree of stochastic behavior, manifested as notable cycle-to-cycle variations in the time of their occurrence.The present study tested whether variation in LCR periodicity contributes to intrinsic (beat-to-beat cycle length variability in single sinoatrial nodal cells.We imaged single rabbit sinoatrial nodal cells using a 2D-camera to capture LCRs over the entire cell, and, in selected cells, simultaneously measured action potentials by perforated patch clamp.LCRs begin to occur on the descending part of the action potential-induced whole-cell Ca(2+ transient, at about the time of the maximum diastolic potential. Shortly after the maximum diastolic potential (mean 54±7.7 ms, n = 14, the ensemble of waxing LCR activity converts the decay of the global Ca(2+ transient into a rise, resulting in a late, whole-cell diastolic Ca(2+ elevation, accompanied by a notable acceleration in diastolic depolarization rate. On average, cells (n = 9 generate 13.2±3.7 LCRs per cycle (mean±SEM, varying in size (7.1±4.2 µm and duration (44.2±27.1 ms, with both size and duration being greater for later-occurring LCRs. While the timing of each LCR occurrence also varies, the LCR period (i.e. the time from the preceding Ca(2+ transient peak to an LCR's subsequent occurrence averaged for all LCRs in a given cycle closely predicts the time of occurrence of the next action potential, i.e. the cycle length.Intrinsic cycle length variability in single sinoatrial nodal cells is linked to beat-to-beat variations in the average period of individual LCRs each cycle.

  2. Current estimates of the energy released following the fission of actinide nuclides

    Science.gov (United States)

    Sonzogni, Alejandro; McCutchan, Elizabeth

    2017-09-01

    We calculate the energy released following the neutron induced fission of the main fuel nuclides in a reactor, 235U, 238U, 239Pu and 241Pu. These energies are used in a number of fields, but we were particularly motivated by their application in the recent measurements of reactor antineutrinos spectra and yields. The calculations are performed using the best estimates of cumulative fission yields for long-lived fission products and the recently released 2016 Atomic Mass Evaluation by Wang et al. Additionally, we obtain more precise values of the energy taken away by antineutrinos by using the latest Total Absorption Gamma Spectroscopy (TAGS) results. An important part of this project is also to obtain realistic estimates of the uncertainties. A comparison with earlier calculations will be presented. Work at Brookhaven National Laboratory was sponsored by the Office of Nuclear Physics, Office of Science of the U.S. Department of Energy under Contract No. DE-AC0298CH10886.

  3. Releasable Kinetic Energy-Based Inertial Control of a DFIG Wind Power Plant

    DEFF Research Database (Denmark)

    Lee, Jinsik; Muljadi, Eduard; Sørensen, Poul Ejnar

    2016-01-01

    Wind turbine generators (WTGs) in a wind power plant (WPP) contain different levels of releasable kinetic energy (KE) because of the wake effects. This paper proposes a releasable KE-based inertial control scheme for a doubly fed induction generator (DFIG) WPP that differentiates the contributions...... of the WTGs depending on their stored KE. The proposed KE-based gain scheme aims to make use of the releasable KE in a WPP to raise the frequency nadir. To achieve this, two additional loops for the inertial control are implemented in each DFIG controller: the rate of change of frequency and droop loops....... The proposed scheme adjusts the two loop gains in a DFIG controller depending on its rotor speed so that a DFIG operating at a higher rotor speed releases more KE. The performance of the proposed scheme was investigated under various wind conditions. The results clearly indicate that the proposed scheme...

  4. Flare Energy Release: Internal Conflict, Contradiction with High Resolution Observations, Possible Solutions

    Science.gov (United States)

    Pustilnik, L.

    2017-06-01

    All accepted paradigm of solar and stellar flares energy release based on 2 whales: 1. Source of energy is free energy of non-potential force free magnetic field in atmosphere above active region; 2. Process of ultrafast dissipation of magnetic fields is Reconnection in Thin Turbulent Current Sheet (RTTCS). Progress in observational techniques in last years provided ultra-high spatial resolution and in physics of turbulent plasma showed that real situation is much more complicated and standard approach is in contradiction both with observations and with problem of RTTCS stability. We present critical analysis of classic models of pre-flare energy accumulation and its dissipation during flare energy release from pioneer works Giovanelli (1939, 1947) up to topological reconnection. We show that all accepted description of global force-free fields as source of future flare cannot be agreed with discovered in last years fine and ultra-fine current-magnetic structure included numerouse arcs-threads with diameters up to 100 km with constant sequence from photosphere to corona. This magnetic skeleton of thin current magnetic threads with strong interaction between them is main source of reserved magnetic energy insolar atmosphere. Its dynamics will be controlled by percolation of magnetic stresses through network of current-magnetic threads with transition to flare state caused by critical value of global current. We show that thin turbulent current sheet is absolutely unstable configuration both caused by splitting to numerous linear currents by dissipative modes like to tearing, and as sequence of suppress of plasma turbulence caused by anomalous heating of turbulent plasma. In result of these factors primary RTTCS will be disrupted in numerous turbulent and normal plasma domains like to resistors network. Current propagation through this network will have percolation character with all accompanied properties of percolated systems: self-organization with formation power

  5. Energy consumption and water-soluble protein release by cell wall disruption of Nannochloropsis gaditana

    NARCIS (Netherlands)

    Safi, C.; Cabas Rodriguez, L.; Mulder, W.J.; Engelen-Smit, N.; Spekking, W.; Broek, van den L.A.M.; Olivieri, G.; Sijtsma, L.

    2017-01-01

    Several cell disruption methods were tested on Nannochloropsis gaditana, to evaluate their efficiency in terms of cell disintegration, energy input and release of soluble proteins. High-pressure homogenization (HPH) and bead milling were the most efficient with >95% cell disintegration, ±50%

  6. Seismic released energy nearby the nuclear waste repository site in Inshas area, Egypt

    International Nuclear Information System (INIS)

    El-hemamy, S.T.; Othman, A.A.A.

    2000-01-01

    A review of the seismicity and seismic history of Egypt indicates some areas of high activity concentrated along Oligocene-Miocene faults. These areas support the idea of recent activation of the Oligocene-Miocene stress cycle. there are similarities in the special distribution of recent and historical epicenters. From the tectonic map of Egypt, the distribution of intensity and magnitude of these epicenters show strong activity along the Nile Delta. This activity might be due to the presence of thick layers of recent alluvial sediments. The released energies of the earthquakes are effective on the structures. The present study deals with the computed released energies of the reported earthquakes in Egypt and around Inshas area. Their effects on the urban and nuclear facilities inside Inshas site are considered. Special consideration will be given to old and new waste repository sites. The application of the determined released energy revealed that Inshas site is affected by seismic activities from five seismo-tectonic source zones, namely the Red Sea, Nile Delta, El-fayum, the mediterranean Sea and the Gulf of Aqaba. El-fayum seismo-tectonic source zone has the maximum effect on the site and gave a high released energy reaching to 1.0E+21 ergs

  7. Regional distribution of released earthquake energy in northern Egypt along with Inahass area

    International Nuclear Information System (INIS)

    El-hemamy, S.T.; Adel, A.A. Othman

    1999-01-01

    A review of the seismic history of Egypt indicates sone areas of high activity concentrated along Oligocene-Miocene faults. These areas support the idea of recent activation of the Oligocene-Miocene stress cycle. There are similarities in the special distribution of recent and historical epicenters. Form the tectonic map of Egypt, distribution of Intensity and magnitude show strong activity along Nile Delta. This due to the presence of a thick layers of recent alluvial sediments. The released energy of the earthquakes are effective on the structures. The present study deals with the computed released energies of the reported earthquakes in Egypt and around Inshas area . Its effect on the urban and nuclear facilities inside Inshas site is considered. Special consideration will be given to old and new waste repository sites. The application of the determined released energy reveals that Inshas site is affected by seismic activity from five seismo-tectonic source zones, namely the Red Sea, Nile Delta, El-Faiyum, the Mediterranean Sea and the Gulf of Aqaba seismo-tectonic zones. El-Faiyum seismo-tectonic source zone has the maximum effect on the site and gave a high released energy reaching to 5.4E +2 1 erg

  8. Fission fragment mass and total kinetic energy distributions of spontaneously fissioning plutonium isotopes

    Science.gov (United States)

    Pomorski, K.; Nerlo-Pomorska, B.; Bartel, J.; Schmitt, C.

    2018-03-01

    The fission-fragment mass and total kinetic energy (TKE) distributions are evaluated in a quantum mechanical framework using elongation, mass asymmetry, neck degree of freedom as the relevant collective parameters in the Fourier shape parametrization recently developed by us. The potential energy surfaces (PES) are calculated within the macroscopic-microscopic model based on the Lublin-Strasbourg Drop (LSD), the Yukawa-folded (YF) single-particle potential and a monopole pairing force. The PES are presented and analysed in detail for even-even Plutonium isotopes with A = 236-246. They reveal deep asymmetric valleys. The fission-fragment mass and TKE distributions are obtained from the ground state of a collective Hamiltonian computed within the Born-Oppenheimer approximation, in the WKB approach by introducing a neck-dependent fission probability. The calculated mass and total kinetic energy distributions are found in good agreement with the data.

  9. The relationship between energy metabolism and the action of inhibitors of histamine release

    DEFF Research Database (Denmark)

    Garland, L G; Johansen, Torben

    1977-01-01

    1 Dextran-induced release of histamine from rat mast cells was inhibited equally in complete and glucose-free Tyrode solution by doxantrazole (0.03-3 micronmol/l), theophylline (0.1-3 mmol/l) and dicumarol (0.01-10 micronmol/litre). 2 Doxantrazole (3 micronmol/l), theophylline (3 mmol/l) and dicu......1 Dextran-induced release of histamine from rat mast cells was inhibited equally in complete and glucose-free Tyrode solution by doxantrazole (0.03-3 micronmol/l), theophylline (0.1-3 mmol/l) and dicumarol (0.01-10 micronmol/litre). 2 Doxantrazole (3 micronmol/l), theophylline (3 mmol...... of histamine release from mast cells incubated in glucose-free solution than in complete Tyrode solution (dose-ratio = 20). Like antimycin A (L MICRONMOL/L), PAPAVERINE (3 MICRONMOL/L) CAUSED A DEPLETION OF MAST CELL ATP that was greater in the absence (85%) than in the presence (25%) of extracellular glucose....... 4 These results suggest that dicumarol, like doxantrazole and theophylline, inhibits histamine release without affecting mast cell energy metabolism. In contrast, papaverine probably inhibits release by depleting ATP that is required for exocytosis. 5 Inhibition of histamine release by dibutyryl...

  10. Forecasting of future earthquakes in the northeast region of India considering energy released concept

    Science.gov (United States)

    Zarola, Amit; Sil, Arjun

    2018-04-01

    This study presents the forecasting of time and magnitude size of the next earthquake in the northeast India, using four probability distribution models (Gamma, Lognormal, Weibull and Log-logistic) considering updated earthquake catalog of magnitude Mw ≥ 6.0 that occurred from year 1737-2015 in the study area. On the basis of past seismicity of the region, two types of conditional probabilities have been estimated using their best fit model and respective model parameters. The first conditional probability is the probability of seismic energy (e × 1020 ergs), which is expected to release in the future earthquake, exceeding a certain level of seismic energy (E × 1020 ergs). And the second conditional probability is the probability of seismic energy (a × 1020 ergs/year), which is expected to release per year, exceeding a certain level of seismic energy per year (A × 1020 ergs/year). The logarithm likelihood functions (ln L) were also estimated for all four probability distribution models. A higher value of ln L suggests a better model and a lower value shows a worse model. The time of the future earthquake is forecasted by dividing the total seismic energy expected to release in the future earthquake with the total seismic energy expected to release per year. The epicentre of recently occurred 4 January 2016 Manipur earthquake (M 6.7), 13 April 2016 Myanmar earthquake (M 6.9) and the 24 August 2016 Myanmar earthquake (M 6.8) are located in zone Z.12, zone Z.16 and zone Z.15, respectively and that are the identified seismic source zones in the study area which show that the proposed techniques and models yield good forecasting accuracy.

  11. Which research for tomorrow's energy? 2012 Energy Colloquium 2. release

    International Nuclear Information System (INIS)

    Antonini, Gerard; Arrif, Teddy; Bain, Pascal; Beguin, Francois; Bruneaux, Gilles; Cetin, Derya; Czernichowski, Isabelle; Escudie, Dany; Folacci, Marie-Ange; Gosse, Kevin; Hareux, Sylvie; Metaye, Romain; Morel, Herve; Odru, Pierre; Oukacine, Linda; Pons, Liz; Tournier, Aline; Corgier, David; Thollin, Jacques; Barret, Mickael; Mosdale, Renaut; Hervouet, Veronique; Pourcelly, Gerald; Brousse, Thierry; Lincot, Daniel; Schmidt-Laine, Claudine; Artero, Vincent; Robinson, Darren; Bigot, Bernard; Salha, Bernard; Minster, Jean-Francois; Hauet, Bertrand

    2012-01-01

    This huge publication gathers interventions and contributions of a colloquium which notably addressed the following issues: bio-energies, hydrogen and fuel cells, energy storage, photovoltaic solar energy, energy efficiency in buildings, transports and industry, CO 2 capture and storage. On the first day, after two interventions on Energies Programmes at the ANR and an overview of R and D world challenges regarding energy, the contributions addressed the above mentioned issues. During the next day, besides these issues, contributions addressed challenges for tomorrow's society and perspectives for research. Thematic sessions addressed bio-energies (optimized production of cellulose ethanol, the third generation, technological deadlocks for the thermal-chemical route), photovoltaic solar energy (new concepts, massive crystalline silicon and photovoltaic thin layers), high energy efficiency buildings, energetic equipment and climate engineering, CO 2 storage, CO 2 capture, fuel cells, hydrogen production, transport and storage, electrochemical and non-electrochemical storage of energy, transports (internal combustion engine and power units, electric transports)

  12. Standing economy: does the heterogeneity in the energy cost of posture maintenance reside in differential patterns of spontaneous weight-shifting?

    Science.gov (United States)

    Miles-Chan, Jennifer L; Fares, Elie-Jacques; Berkachy, Redina; Jacquet, Philippe; Isacco, Laurie; Schutz, Yves; Montani, Jean-Pierre; Dulloo, Abdul G

    2017-04-01

    Due to sedentarity-associated disease risks, there is much interest in methods to increase low-intensity physical activity. In this context, it is widely assumed that altering posture allocation can modify energy expenditure (EE) to impact body-weight regulation and health. However, we have recently shown the existence of two distinct phenotypes pertaining to the energy cost of standing-with most individuals having no sustained increase in EE during steady-state standing relative to sitting comfortably. Here, we investigated whether these distinct phenotypes are related to the presence/absence of spontaneous "weight-shifting", i.e. the redistribution of body-weight from one foot to the other. Using indirect calorimetry to measure EE in young adults during sitting and 10 min of steady-state standing, we examined: (i) heterogeneity in EE during standing (n = 36); (ii) EE and spontaneous weight-shifting patterns (n = 18); (iii) EE during spontaneous weight-shifting versus experimentally induced weight-shifting (n = 7), and; (iv) EE during spontaneous weight-shifting versus intermittent leg/body displacement (n = 6). Despite heterogeneity in EE response to steady-state standing, no differences were found in the amount or pattern of spontaneous weight-shifting between the two phenotypes. Whilst experimentally induced weight-shifting resulted in a mean EE increase of only 11% (range: 0-25%), intermittent leg/body displacement increased EE to >1.5 METs in all participants. Although the variability in spontaneous weight-shifting signatures between individuals does not appear to underlie heterogeneity in the energy cost of standing posture maintenance, these studies underscore the fact that leg/body displacement, rather than standing posture alone, is needed to increase EE above the currently defined sedentary threshold.

  13. Blast Shock Wave Mitigation Using the Hydraulic Energy Redirection and Release Technology

    Science.gov (United States)

    Chen, Yun; Huang, Wei; Constantini, Shlomi

    2012-01-01

    A hydraulic energy redirection and release technology has been developed for mitigating the effects of blast shock waves on protected objects. The technology employs a liquid-filled plastic tubing as a blast overpressure transformer to transfer kinetic energy of blast shock waves into hydraulic energy in the plastic tubings. The hydraulic energy is redirected through the plastic tubings to the openings at the lower ends, and then is quickly released with the liquid flowing out through the openings. The samples of the specifically designed body armor in which the liquid-filled plastic tubings were installed vertically as the outer layer of the body armor were tested. The blast test results demonstrated that blast overpressure behind the body armor samples was remarkably reduced by 97% in 0.2 msec after the liquid flowed out of its appropriate volume through the openings. The results also suggested that a volumetric liquid surge might be created when kinetic energy of blast shock wave was transferred into hydraulic energy to cause a rapid physical movement or displacement of the liquid. The volumetric liquid surge has a strong destructive power, and can cause a noncontact, remote injury in humans (such as blast-induced traumatic brain injury and post-traumatic stress disorder) if it is created in cardiovascular system. The hydraulic energy redirection and release technology can successfully mitigate blast shock waves from the outer surface of the body armor. It should be further explored as an innovative approach to effectively protect against blast threats to civilian and military personnel. PMID:22745740

  14. Blast shock wave mitigation using the hydraulic energy redirection and release technology.

    Directory of Open Access Journals (Sweden)

    Yun Chen

    Full Text Available A hydraulic energy redirection and release technology has been developed for mitigating the effects of blast shock waves on protected objects. The technology employs a liquid-filled plastic tubing as a blast overpressure transformer to transfer kinetic energy of blast shock waves into hydraulic energy in the plastic tubings. The hydraulic energy is redirected through the plastic tubings to the openings at the lower ends, and then is quickly released with the liquid flowing out through the openings. The samples of the specifically designed body armor in which the liquid-filled plastic tubings were installed vertically as the outer layer of the body armor were tested. The blast test results demonstrated that blast overpressure behind the body armor samples was remarkably reduced by 97% in 0.2 msec after the liquid flowed out of its appropriate volume through the openings. The results also suggested that a volumetric liquid surge might be created when kinetic energy of blast shock wave was transferred into hydraulic energy to cause a rapid physical movement or displacement of the liquid. The volumetric liquid surge has a strong destructive power, and can cause a noncontact, remote injury in humans (such as blast-induced traumatic brain injury and post-traumatic stress disorder if it is created in cardiovascular system. The hydraulic energy redirection and release technology can successfully mitigate blast shock waves from the outer surface of the body armor. It should be further explored as an innovative approach to effectively protect against blast threats to civilian and military personnel.

  15. Blast shock wave mitigation using the hydraulic energy redirection and release technology.

    Science.gov (United States)

    Chen, Yun; Huang, Wei; Constantini, Shlomi

    2012-01-01

    A hydraulic energy redirection and release technology has been developed for mitigating the effects of blast shock waves on protected objects. The technology employs a liquid-filled plastic tubing as a blast overpressure transformer to transfer kinetic energy of blast shock waves into hydraulic energy in the plastic tubings. The hydraulic energy is redirected through the plastic tubings to the openings at the lower ends, and then is quickly released with the liquid flowing out through the openings. The samples of the specifically designed body armor in which the liquid-filled plastic tubings were installed vertically as the outer layer of the body armor were tested. The blast test results demonstrated that blast overpressure behind the body armor samples was remarkably reduced by 97% in 0.2 msec after the liquid flowed out of its appropriate volume through the openings. The results also suggested that a volumetric liquid surge might be created when kinetic energy of blast shock wave was transferred into hydraulic energy to cause a rapid physical movement or displacement of the liquid. The volumetric liquid surge has a strong destructive power, and can cause a noncontact, remote injury in humans (such as blast-induced traumatic brain injury and post-traumatic stress disorder) if it is created in cardiovascular system. The hydraulic energy redirection and release technology can successfully mitigate blast shock waves from the outer surface of the body armor. It should be further explored as an innovative approach to effectively protect against blast threats to civilian and military personnel.

  16. Energy optimization through probabilistic annual forecast water release technique for major storage hydroelectric reservoir

    International Nuclear Information System (INIS)

    Abdul Bahari Othman; Mohd Zamri Yusoff

    2006-01-01

    One of the important decisions to be made by the management of hydroelectric power plant associated with major storage reservoir is to determine the best turbine water release decision for the next financial year. The water release decision enables firm energy generated estimation for the coming financial year to be done. This task is usually a simple and straightforward task provided that the amount of turbine water release is known. The more challenging task is to determine the best water release decision that is able to resolve the two conflicting operational objectives which are minimizing the drop of turbine gross head and maximizing upper reserve margin of the reservoir. Most techniques from literature emphasize on utilizing the statistical simulations approach. Markovians models, for example, are a class of statistical model that utilizes the past and the present system states as a basis for predicting the future [1]. This paper illustrates that rigorous solution criterion can be mathematically proven to resolve those two conflicting operational objectives. Thus, best water release decision that maximizes potential energy for the prevailing natural inflow is met. It is shown that the annual water release decision shall be made in such a manner that annual return inflow that has return frequency smaller than critical return frequency (f c ) should not be considered. This criterion enables target turbine gross head to be set to the well-defined elevation. In the other words, upper storage margin of the reservoir shall be made available to capture magnitude of future inflow that has return frequency greater than or equal to f c. A case study is shown to demonstrate practical application of the derived mathematical formulas

  17. The Temperature Condition of the Plate with Temperature-Dependent Thermal Conductivity and Energy Release

    Directory of Open Access Journals (Sweden)

    V. S. Zarubin

    2016-01-01

    Full Text Available The temperature state of a solid body, in addition to the conditions of its heat exchange with the environment, can greatly depend on the heat release (or heat absorption processes within the body volume. Among the possible causes of these processes should be noted such as a power release in the fuel elements of nuclear reactors, exothermic or endothermic chemical reactions in the solid body material, which respectively involve heat release or absorbtion, heat transfer of a part of the electric power in the current-carrying conductors (so-called Joule’s heat or the energy radiation penetrating into the body of a semitransparent material, etc. The volume power release characterizes an intensity of these processes.The extensive list of references to the theory of heat conductivity of solids offers solutions to problems to determine a stationary (steady over time and non-stationary temperature state of the solids (as a rule, of the canonical form, which act as the sources of volume power release. Thus, in general case, a possibility for changing power release according to the body volume and in solving the nonstationary problems also a possible dependence of this value on the time are taken into consideration.However, in real conditions the volume power release often also depends on the local temperature, and such dependence can be nonlinear. For example, with chemical reactions the intensity of heat release or absorption is in proportion to their rate, which, in turn, is sensitive to the temperature value, and a dependence on the temperature is exponential. A further factor that in such cases makes the analysis of the solid temperature state complicated, is dependence on the temperature and the thermal conductivity of this body material, especially when temperature distribution therein  is significantly non-uniform. Taking into account the influence of these factors requires the mathematical modeling methods, which allow us to build an adequate

  18. Data Analysis of Transient Energy Releases in the LHC Superconducting Dipole Magnets

    CERN Document Server

    Calvi, M; Bottura, L; Di Castro, M; Masi, A; Siemko, A

    2007-01-01

    Premature training quenches are caused by transient energy released within the LHC dipole magnet coils while it is energized. Voltage signals recorded across the magnet coils and on the so-called quench antenna carry information about these disturbances. The transitory events correlated to transient energy released are extracted making use of continuous wavelet transform. Several analyses are performed to understand their relevance to the so called training phenomenon. The statistical distribution of the signals amplitude, the number of events occurring at a given current level, the average frequency content of the events are the main parameters on which the analysis have been focalized. Comparisons among different regions of the magnet, among different quenches in the same magnet and among magnets made by different builders are reported. Conclusions about the efficiency of the raw data treatment and the relevance of the parameters developed with respect to the magnet global behavior are finally given.

  19. Electron transfer rates and energy releases during denitrification of municipal wastewater

    DEFF Research Database (Denmark)

    Abdul-Talib, S.; Ujang, Z; Vollertsen, J.

    2004-01-01

    could be simplified by a two-stage process. In the first stage, nitrate was utilised with significant accumulation of nitrite. In the second stage nitrite was utilised when nitrate depleted. Denitrification rates during the two stages were expressed in terms of electron equivalents (e-eq.) in order...... to compare the process when differennt electron acceptors namlely, nitrate and nitrite were utilised. The energy release rates during the two stages were calculated and compared....

  20. Status of JENDL High Energy File. Evaluation method, tools, specification, release procedure, etc

    Energy Technology Data Exchange (ETDEWEB)

    Fukahori, Tokio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-11-01

    The ENDF-6 format file should be kept as a standard distribution file and it is not difficult to convert into some other form for code`s libraries. From this point of view, status of JENDL High Energy File is introduced in this report as well as evaluation strategy, recommended specification, stored nuclides and quantities, a format structure, evaluation methods and tools, and release plan. (author)

  1. Energy release and its containment within thin-walled, backed vessels

    International Nuclear Information System (INIS)

    Chambers, D.I.

    1983-01-01

    The problem adressed is the containment of a sudden release of energy of a magnitude up to 4 x 10 11 joules in a reusable vessel. The design process began by formulating dynamic models for both the input to such a vessel and the vessel itself and using these models to generate a general response. Modifications to the input and a more specific response are discussed. Computer codes used in calculations are described and listed

  2. Thermal desorption and bombardment-induced release of deuterium implanted into stainless steels at low energy

    International Nuclear Information System (INIS)

    Farrell, G.; Donnelly, S.E.

    1978-01-01

    Thermal desorption spectra have been obtained for low energy (15-750 eV) deuterons implanted into types 321 and 304 stainless steel, to total fluences in the range 10 13 - 10 17 deuterons/cm 2 . In each case the spectra show a peak at about 350 K, but in the 321 steel there is a second peak in the region of 900 K, the population and peak temperature of which increase with energy. Activation energies of 0.99 and 2.39 eV and a rate constant of 7 x 10 15 /s have been derived for the peaks and it is thought that the first peak corresponds to release from sites close to the surface, while the second peak may be related to trapping at impurities such as Ti. Measurements have also been made of the release of deuterium resulting from post-implantation bombardment with hydrogen ions. It is found that depletion of the first peak in the 321 steel is the result of gas sputtering, but depletion of the second peak is the result of the formation of HD during desorption, while depletion of the peak in the 304 stainless steel also results from HD formation even though this peak is the same as the first peak in the 321 steel. Estimates have also been made of the deuterium self-sputtering cross section at various energies, which show a monotonic decrease as energy increases. (Auth.)

  3. Effect of Nd:YAG laser pulse energy on mercury vapor release from the dental amalgam.

    Science.gov (United States)

    Oskoee, Siavash Savadi; Bahari, Mahmoud; Kimyai, Soodabeh; Rikhtegaran, Sahand; Puralibaba, Firooz; Ajami, Hamidreza

    2013-10-01

    The aim of this study was to evaluate the effect of different pulse energies of Nd:YAG laser on the amalgam ablation, and its effect on the amount of mercury vapor release from amalgam. Toxic vapor release from amalgam restorations at the laser focus site is possible. Forty-five amalgam samples (4 mm in diameter and 5 mm in height) were placed in sealed containers and underwent Nd:YAG laser irradiation with pulse energies of 50, 150, and 250 mJ at a distance of 1 mm from the amalgam surface for 4 sec. Subsequently, 150 mL of air was collected from the inside of the container using an Apex Pump to analyze the amount of mercury vapor in the air samples using a mercury vapor analyzer. Data were analyzed using Kruskal-Wallis and Mann-Whitney U tests (pppamalgam surface, which increased in size with an increase in the energy of the laser beam. The amount of mercury vapor significantly increased with an increase in the pulse energy of the laser beam, and was significantly higher than the standard mercury vapor concentration with 250 mJ pulse energy.

  4. Anisotropic kinetic energy release and gyroscopic behavior of CO2 super rotors from an optical centrifuge

    Science.gov (United States)

    Murray, Matthew J.; Ogden, Hannah M.; Mullin, Amy S.

    2017-10-01

    An optical centrifuge is used to generate an ensemble of CO2 super rotors with oriented angular momentum. The collision dynamics and energy transfer behavior of the super rotor molecules are investigated using high-resolution transient IR absorption spectroscopy. New multipass IR detection provides improved sensitivity to perform polarization-dependent transient studies for rotational states with 76 ≤ J ≤ 100. Polarization-dependent measurements show that the collision-induced kinetic energy release is spatially anisotropic and results from both near-resonant energy transfer between super rotor molecules and non-resonant energy transfer between super rotors and thermal molecules. J-dependent studies show that the extent and duration of the orientational anisotropy increase with rotational angular momentum. The super rotors exhibit behavior akin to molecular gyroscopes, wherein molecules with larger amounts of angular momentum are less likely to change their angular momentum orientation through collisions.

  5. Differences in Adverse Event Reporting Rates of Therapeutic Failure Between Two Once-daily Extended-release Methylphenidate Medications in Canada: Analysis of Spontaneous Adverse Event Reporting Databases.

    Science.gov (United States)

    Park-Wyllie, Laura; van Stralen, Judy; Castillon, Genaro; Sherman, Stephen E; Almagor, Doron

    2017-10-01

    Our study evaluated adverse events of therapeutic failure (and specifically reduced duration of action) with the use of a branded product, Osmotic Release Oral System (OROS) methylphenidate, which is approved for the treatment of attention deficit/hyperactivity disorder, and a generic product (methylphenidate, methylphenidate ER-C), which was approved for marketing in Canada based on bioequivalence to OROS methylphenidate. This study was initiated following reports that some US-marketed generic methylphenidate ER products had substantially higher reporting rates of therapeutic failure than did the referenced brands. Through methodology similar to that used by the US Food and Drug Administration to investigate the issue with the US-marketed generic, reporting rates were calculated from cases of therapeutic failure identified in the Canadian Vigilance Adverse Reaction Online database for a 1-year period beginning 8 months after each product launch. Corresponding population exposure was estimated from the number of tablets dispensed. An in-depth analysis of narratives of individual case safety reports (ICSRs) with the use of the generic product was conducted in duplicate by 2 physicians to assess causality and to characterize the potential safety risk and clinical pattern of therapeutic failure. Similar secondary analyses were conducted on the US-marketed products. Reporting rates of therapeutic failure with the use of methylphenidate ER-C (generic) and OROS methylphenidate (brand name) were 411.5 and 37.5 cases per 100,000 patient-years, respectively (reporting rate ratio, 10.99; 95% CI, 5.93-22.21). In-depth analysis of narratives of 230 ICSRs of therapeutic failure with the Canadian-marketed generic determined that all ICSRs were either probably (60 [26%]) or possibly (170 [74%]) causally related to methylphenidate ER-C. Clinical symptoms suggestive of overdose were present in 31 reports of loss of efficacy (13.5%) and occurred primarily in the morning, and

  6. Noninvasive Fluorescence Resonance Energy Transfer Imaging of in vivo Premature Drug Release from Polymeric Nanoparticles

    Science.gov (United States)

    Zou, Peng; Chen, Hongwei; Paholak, Hayley J.; Sun, Duxin

    2013-01-01

    Understanding in vivo drug release kinetics is critical for the development of nanoparticle-based delivery systems. In this study, we developed a fluorescence resonance energy transfer (FRET) imaging approach to noninvasively monitor in vitro and in vivo cargo release from polymeric nanoparticles. The FRET donor dye (DiO or DiD) and acceptor dye (DiI or DiR) were individually encapsulated into poly(ethylene oxide)-b-polystyrene (PEO-PS) nanoparticles. When DiO (donor) nanoparticles and DiI (acceptor) nanoparticles were co-incubated with cancer cells for 2 h, increased FRET signals were observed from cell membranes, suggesting rapid release of DiO and DiI to cell membranes. Similarly, increased FRET ratios were detected in nude mice after intravenous co-administration of DiD (donor) nanoparticles and DiR (acceptor) nanoparticles. In contrast, another group of nude mice i.v. administrated with DiD/DiR co-loaded nanoparticles showed decreased FRET ratios. Based on the difference in FRET ratios between the two groups, in vivo DiD/DiR release half-life from PEO-PS nanoparticles was determined to be 9.2 min. In addition, it was observed that the presence of cell membranes facilitated burst release of lipophilic cargos while incorporation of oleic acid-coated iron oxide into PEO-PS nanoparticles slowed the release of DiD/DiR to cell membranes. The developed in vitro and in vivo FRET imaging techniques can be used to screening stable nano-formulations for lipophilic drug delivery. PMID:24033270

  7. Energy release from a stream of infalling prominence debris on 2011 September 7-8

    Science.gov (United States)

    Inglis, A. R.; Gilbert, H. R.; Ofman, L.

    2017-12-01

    In recent years high-resolution and high-cadence EUV imaging has revealed a new phenomenon, impacting prominence debris, where prominence material from failed or partial eruptions can impact the lower atmosphere and release energy. We present a clear example of this phenomenon occurring on 2011 September 7-8. The initial eruption of prominence material was associated with an X1.8-class flare from AR11283, occurring at 22:30 UT on 2011 September 7, resulting in a semi-continuous stream of this material returning to the solar surface between 00:20 - 00:40 UT on 2011 September 8. A substantial area remote from the original active region experienced brightening in multiple EUV channels observed by SDO/AIA. Using the differential emission measure, we estimated the energetic properties of this event. We found that the radiated energy of the impacted plasma was of order 10^27 ergs, while the upper limit on the thermal energy peaked at 10^28 ergs. Based on these estimates we were able to determine the mass content of the debris to be in the range 2x10^14 energy release takes place during these events, and that such impacts may be used as a novel diagnostic tool for investigating prominence material properties.

  8. ENERGY RELEASE AND TRANSFER IN SOLAR FLARES: SIMULATIONS OF THREE-DIMENSIONAL RECONNECTION

    International Nuclear Information System (INIS)

    Birn, J.; Fletcher, L.; Hesse, M.; Neukirch, T.

    2009-01-01

    Using three-dimensional magnetohydrodynamic simulations we investigate energy release and transfer in a three-dimensional extension of the standard two-ribbon flare picture. In this scenario, reconnection is initiated in a thin current sheet (suggested to form below a departing coronal mass ejection) above a bipolar magnetic field. Two cases are contrasted: an initially force-free current sheet (low beta) and a finite-pressure current sheet (high beta), where beta represents the ratio between gas (plasma) and magnetic pressure. The energy conversion process from reconnection consists of incoming Poynting flux turned into up- and downgoing Poynting flux, enthalpy flux, and bulk kinetic energy flux. In the low-beta case, the outgoing Poynting flux is the dominant contribution, whereas the outgoing enthalpy flux dominates in the high-beta case. The bulk kinetic energy flux is only a minor contribution in the downward direction. The dominance of the downgoing Poynting flux in the low-beta case is consistent with an alternative to the thick target electron beam model for solar flare energy transport, suggested recently by Fletcher and Hudson, whereas the enthalpy flux may act as an alternative transport mechanism. For plausible characteristic parameters of the reconnecting field configuration, we obtain energy release timescales and energy output rates that compare favorably with those inferred from observations for the impulsive phase of flares. Significant enthalpy flux and heating are found even in the initially force-free case with very small background beta, resulting mostly from adiabatic compression rather than Ohmic dissipation. The energy conversion mechanism is most easily understood as a two-step process (although the two steps may occur essentially simultaneously): the first step is the acceleration of the plasma by Lorentz forces in layers akin to the slow shocks in the Petschek reconnection model, involving the conversion of magnetic energy to bulk kinetic

  9. Experiment calculated ascertainment of factors affecting the energy release in IGR reactor core

    International Nuclear Information System (INIS)

    Kurpesheva, A.M.; Zhotabayev, Zh.R.

    2006-01-01

    Full text: At present energy supply resources problem is important. Nuclear reactors can, of course, solve this problem, but at the same time there is another issue, concerning safety exploitation of nuclear reactors. That is why, for the last seven years, such experiments as 'Investigation of the processes, conducting severe accidents with core melting' are being carried out at our IGR (impulse graphite reactor) reactor. Leaving out other difficulties of such experiments, it is necessary to notice, that such experiments require more accurate IGR core energy release calculations. The final aim of the present research is verification and correction of the existing method or creation of new method of IGR core energy release calculation. IGR reactor is unique and there is no the same reactor in the world. Therefore, application of the other research reactor methods here is quite useful. This work is based on evaluation of factors affecting core energy release (physical weight of experimental device, different configuration of reactor core, i.e. location of absorbers, initial temperature of core, etc), as well as interference of absorbers group. As it is known, energy release is a value of integral reactor power. During experiments with rays, Reactor power depends on currents of ion production chambers (IPC), located round the core. It is worth to notice that each ion production chamber (IPC) in the same start-up has its own ratio coefficient between IPC current and reactor present power. This task is complicated due to 'IPC current - reactor power' ratio coefficients, that change continuously, probably, because of new loading of experimental facility and different position of control rods. That is why, in order to try about reactor power, before every start-up, we have to re-determine the 'IPC current - reactor power' ratio coefficients for each ion production chamber (IPC). Therefore, the present work will investigate the behavior of ratio coefficient within the

  10. Fundamentals of Reservoir Surface Energy as Related to Surface Properties, Wettability, Capillary Action, and Oil Recovery from Fractured Reservoirs by Spontaneous Imbibition

    Energy Technology Data Exchange (ETDEWEB)

    Norman Morrow; Herbert Fischer; Yu Li; Geoffrey Mason; Douglas Ruth; Siddhartha Seth; Zhengxin Tong; Evren Unsal; Siluni Wickramathilaka; Shaochang Wo; Peigui Yin

    2008-06-30

    The objective of this project is to increase oil recovery from fractured reservoirs through improved fundamental understanding of the process of spontaneous imbibition by which oil is displaced from the rock matrix into the fractures. Spontaneous imbibition is fundamentally dependent on the reservoir surface free energy but this has never been investigated for rocks. In this project, the surface free energy of rocks will be determined by using liquids that can be solidified within the rock pore space at selected saturations. Thin sections of the rock then provide a two-dimensional view of the rock minerals and the occupant phases. Saturations and oil/rock, water/rock, and oil/water surface areas will be determined by advanced petrographic analysis and the surface free energy which drives spontaneous imbibition will be determined as a function of increase in wetting phase saturation. The inherent loss in surface free energy resulting from capillary instabilities at the microscopic (pore level) scale will be distinguished from the decrease in surface free energy that drives spontaneous imbibition. A mathematical network/numerical model will be developed and tested against experimental results of recovery versus time over broad variation of key factors such as rock properties, fluid phase viscosities, sample size, shape and boundary conditions. Two fundamentally important, but not previously considered, parameters of spontaneous imbibition, the capillary pressure acting to oppose production of oil at the outflow face and the pressure in the non-wetting phase at the no-flow boundary versus time, will also be measured and modeled. Simulation and network models will also be tested against special case solutions provided by analytic models. In the second stage of the project, application of the fundamental concepts developed in the first stage of the project will be demonstrated. The fundamental ideas, measurements, and analytic/numerical modeling will be applied to mixed

  11. FUNDAMENTALS OF RESERVOIR SURFACE ENERGY AS RELATED TO SURFACE PROPERTIES, WETTABILITY, CAPILLARY ACTION, AND OIL RECOVERY FROM FRACTURED RESERVOIRS BY SPONTANEOUS IMBIBITION

    Energy Technology Data Exchange (ETDEWEB)

    Norman R. Morrow; Herbert Fischer; Yu Li; Geoffrey Mason; Douglas Ruth; Siddhartha Seth; Peigui Yin; Shaochang Wo

    2004-10-01

    The objective of this project is to increase oil recovery from fractured reservoirs through improved fundamental understanding of the process of spontaneous imbibition by which oil is displaced from the rock matrix into the fractures. Spontaneous imbibition is fundamentally dependent on the reservoir surface free energy but this has never been investigated for rocks. In this project, the surface free energy of rocks will be determined by using liquids that can be solidified within the rock pore space at selected saturations. Thin sections of the rock then provide a two-dimensional view of the rock minerals and the occupant phases. Saturations and oil/rock, water/rock, and oil/water surface areas will be determined by advanced petrographic analysis and the surface free energy which drives spontaneous imbibition will be determined as a function of increase in wetting phase saturation. The inherent loss in surface free energy resulting from capillary instabilities at the microscopic (pore level) scale will be distinguished from the decrease in surface free energy that drives spontaneous imbibition. A mathematical network/numerical model will be developed and tested against experimental results of recovery versus time over broad variation of key factors such as rock properties, fluid phase viscosities, sample size, shape and boundary conditions. Two fundamentally important, but not previously considered, parameters of spontaneous imbibition, the capillary pressure acting to oppose production of oil at the outflow face and the pressure in the nonwetting phase at the no-flow boundary versus time, will also be measured and modeled. Simulation and network models will also be tested against special case solutions provided by analytic models. In the second stage of the project, application of the fundamental concepts developed in the first stage of the project will be demonstrated. The fundamental ideas, measurements, and analytic/numerical modeling will be applied to mixed

  12. Fundamentals of reservoir surface energy as related to surface properties, wettability, capillary action, and oil recovery from fractured reservoirs by spontaneous imbibition

    Energy Technology Data Exchange (ETDEWEB)

    Norman R. Morrow; Herbert Fischer; Yu Li; Geoffrey Mason; Douglas Ruth; Siddhartha Seth; Jason Zhengxin Tong; Peigui Yin; Shaochang Wo

    2006-06-08

    The objective of this project is to increase oil recovery from fractured reservoirs through improved fundamental understanding of the process of spontaneous imbibition by which oil is displaced from the rock matrix into the fractures. Spontaneous imbibition is fundamentally dependent on the reservoir surface free energy but this has never been investigated for rocks. In this project, the surface free energy of rocks will be determined by using liquids that can be solidified within the rock pore space at selected saturations. Thin sections of the rock then provide a two-dimensional view of the rock minerals and the occupant phases. Saturations and oil/rock, water/rock, and oil/water surface areas will be determined by advanced petrographic analysis and the surface free energy which drives spontaneous imbibition will be determined as a function of increase in wetting phase saturation. The inherent loss in surface free energy resulting from capillary instabilities at the microscopic (pore level) scale will be distinguished from the decrease in surface free energy that drives spontaneous imbibition. A mathematical network/numerical model will be developed and tested against experimental results of recovery versus time over broad variation of key factors such as rock properties, fluid phase viscosities, sample size, shape and boundary conditions. Two fundamentally important, but not previously considered, parameters of spontaneous imbibition, the capillary pressure acting to oppose production of oil at the outflow face and the pressure in the non-wetting phase at the no-flow boundary versus time, will also be measured and modeled. Simulation and network models will also be tested against special case solutions provided by analytic models. In the second stage of the project, application of the fundamental concepts developed in the first stage of the project will be demonstrated. The fundamental ideas, measurements, and analytic/numerical modeling will be applied to mixed

  13. Status of emission release and associated problems in energy systems analysis

    International Nuclear Information System (INIS)

    Yasukawa, Shigeru; Mankin, Shuichi; Sato, Osamu; Koyama, Shigeo; Ihara, Seijiro.

    1987-11-01

    OECD/IEA/ETSAP (Energy Technology System Analysis Project) has been started in March 1976. Since initiation of the projects, JAERI and ETL (Electrotechnical Laboratory) have been participating in the projects as operating agent of Japan. From last October, the ETSAP has initiated its Annex III programme, which pursues the problems laid down in energy-environment relationships. Main research objective of the programme is to investigate through the systems analysis ''how various environmental constrains would affect the pattern of fuel and technology use and the choice and timing of implementation of abatement technologies''. In this report, we describe the status of emission release in Japan and associated problems in energy system analysis which has been investigated at the start of these research programme mentioned above. (author)

  14. Spontaneous pneumothorax

    Directory of Open Access Journals (Sweden)

    Davari R

    1996-07-01

    Full Text Available A case with bilateral spontaneous pneumothorax was presented. Etiology, mechanism, and treatment were discussed on the review of literature. Spontaneous Pneumothorax is a clinical entity resulting from a sudden non traumatic rupture of the lung. Biach reported in 1880 that 78% of 916 patients with spontaneous pneumothorax had tuberculosis. Kjergaard emphasized 1932 the primary importance of subpleural bleb disease. Currently the clinical spectrum of spontaneous pneumothorax seems to have entered a third era with the recognition of the interstitial lung disease and AIDS as a significant etiology. Standard treatment is including: observation, thoracocentesis, tube thoracostomy. Chemical pleurodesis, bullectomy or wedge resection of lung with pleural abrasion and occasionally pleurectomy. Little information has been reported regarding the efficacy of such treatment in spontaneous pneumothorax secondary to non bleb disease

  15. Dividing by four CO2 releases due to energy: the Negatep scenario

    International Nuclear Information System (INIS)

    Acket, C.; Bacher, P.

    2011-01-01

    The Negatep scenario aims at dividing CO 2 releases by 4, which means, more or less, dividing the consumption of fossil energies by the same factor, in order to comply with the French 2005 energy act. After a description of the situation in 2006, of trends, and a recall of the objectives defined by the 'Grenelle de l'Environnement' regarding energy savings and renewable energies, the authors show that reaching such a reduction requires to: decrease to nearly zero oil and gas in the residential and tertiary sectors, reduce significantly the use of oil in the transport sector, reduce significantly the use of fossil fuels in industry, increase massively the share of electricity in the energy mix, maintain the share of nuclear in the electricity generation and, as long as the storage of electricity is not developed, limit the share of intermittent energies to a level compatible with that of gas turbines. The study shows that the proposed measures can fulfill the objectives for 2020 proposed by the 'Grenelle de l'Environnement'

  16. Using Sdo's AIA to Investigate Energy Transport from a Flare's Energy Release Site to the Chromosphere

    Science.gov (United States)

    Brosius, Jeffrey W.; Holman, Gordon D.

    2012-01-01

    Coordinated observations of a GOES B4.8 microflare with SDOs Atmospheric Imaging Assembly (AIA) and the RamatyHigh Energy Solar Spectroscopic Imager (RHESSI) on 2010 July 31 show that emission in all seven of AIAs EUV channels brightened simultaneously nearly 6 min before RHESSI or GOES detected emission from plasma at temperatures around 10 MK. Aims. To help interpret these and AIA flare observations in general, we characterized the expected temporal responses of AIAs 94, 131, 171, 193, 211, and 335 channels to solar flare brightenings by combining (1) AIAs nominal temperature response functions available through SSWIDL with (2) EUV spectral line data observed in a flare loop Coordinated observations of a GOES B4.8 microflare with SDOs Atmospheric Imaging Assembly (AIA) and the RamatyHigh Energy Solar Spectroscopic Imager (RHESSI) on 2010 July 31 show that emission in all seven of AIAs EUV channels brightenedsimultaneously nearly 6 min before RHESSI or GOES detected emission from plasma at temperatures around 10 MK.Aims. To help interpret these and AIA flare observations in general, we characterized the expected temporal responses of AIAs 94,131, 171, 193, 211, and 335 channels to solar flare brightenings by combining (1) AIAs nominal temperature response functionsavailable through SSWIDL with (2) EUV spectral line data observed in a flare loop

  17. Quasi-static method and finite element method for obtaining the modifications of the spontaneous emission rate and energy level shift near a plasmonic nanostructure.

    Science.gov (United States)

    Zhao, Yun-Jin; Tian, Meng; Wang, Xiao-Yun; Yang, Hong; Zhao, Heping; Huang, Yong-Gang

    2018-01-22

    We provide numerical demonstrations of the applicability and accuracy of the quasi-static method and the finite-element method in the investigation of the modifications of the spontaneous emission rate and the energy level shift of an emitter placed near a silver-air interface or a silver nano-sphere. The analytical results are presented as a reference. Our calculations show that the finite element method is an accurate and general method. For frequency away from the radiative mode, the quasi-static method can be applied more effectively for calculating the energy level shift than the spontaneous emission rate. But for frequency around, there is a blue shift for both and this shift increases with the increasing of emitter-silver distance. Applying the theory to the nanosphere dimmer, we see similar phenomenon and find extremely large modifications of the spontaneous emission rate and energy level shift. These findings are instructive in the fields of quantum light-matter interactions.

  18. Influence of ceramic dental crown coating substrate thickness ratio on strain energy release rate

    Science.gov (United States)

    Khasnulhadi, K.; Daud, R.; Mat, F.; Noor, S. N. F. M.; Basaruddin, K. S.; Sulaiman, M. H.

    2017-10-01

    This paper presents the analysis of coating substrate thickness ratio effect on the crown coating fracture behaviour. The bi-layer material is examined under four point bending with pre-crack at the bottom of the core material by using finite element. Three different coating thickness of core/substrate was tested which is 1:1, 1:2 and 2:1. The fracture parameters are analysed based on bilayer and homogenous elastic interaction. The result shows that the ratio thickness of core/veneer provided a significant effect on energy release rate.

  19. Two Stages of The Energy Release of Explosive Decomposition of Heavy Metals Azides

    Science.gov (United States)

    Aluker, E. D.; Belokurov, G. M.; Krechetov, A. G.; Aduev, B. P.; Loboyko, B. G.; Filin, V. P.

    2006-08-01

    Methods of high time-resolution spectroscopy were used to determine two stages of explosive luminescence in solid energetic materials: the pre-explosive stage and the stage of processes occurring in explosion products. It was experimentally established that in silver azides the heating of a sample at the end of the pre-explosive stage does not exceed ˜ 300 K; while at the second stage the temperature of the explosion products reaches ˜ 3000 K. As it follows from the data obtained the major portion (˜ 90%) of the energy released during the explosion in AgN3 is associated with the processes occurring in the explosion products.

  20. Nitrogen recombination dynamics at Cu(111): Rotational energy release and product angular distributions

    Science.gov (United States)

    Murphy, M. J.; Skelly, J. F.; Hodgson, A.

    1998-09-01

    Nitrogen atoms adsorbed on Cu(111) desorb thermally from an ordered Cu(100)-c(2×2)N phase in a sharp, zero order desorption feature near 700 K with an activation barrier of 143 kJ mol-1. Detailed N2 product rovibrational state distributions have been measured following recombinative desorption from a 700 K Cu(111) surface exposed to a N atom beam, with an equilibrium N coverage θN⩽10-2 ML. Although desorbing N2 is translationally and vibrationally hot, with a vibrational temperature of 5100 K and 4.2 eV of translational excitation perpendicular to the surface, rotation is excited with a temperature of just 910(±50) K for the vibrational ground state and 840(±250) K for (v=1). The energy released during recombinative desorption channels effectively into translational and vibrational motion, but not into rotational excitation. The angular distribution of recombinatively desorbed N2 is sharply peaked along the surface normal, P(θ)=cos(28±1) θ, indicating a mean energy release of 0.28 eV into translation parallel to the surface. This is inconsistent with 1D models of the translational energy release based on thermal motion parallel to the surface and a repulsive energy release directed along the surface normal. The dynamics can be described by a direct, repulsive model with a transition state at extended N2 separation, similar to the models developed for H2 dissociation on the same surface. We discuss the application of detailed balance to determine N2 sticking functions S(E,v,J) and, using a simple model for these functions, estimate a rotational efficacy of ˜0.23 for sticking of N2(v=0, J⩽24) and a vibrational efficacy of 0.7 for N2(v=1). The dynamics are compared to the models developed for H2 dissociation and the role of molecular chemisorption states and the local desorption site discussed.

  1. Relationship between ERR and seismic energy release for different geotechnical areas.

    CSIR Research Space (South Africa)

    Spottiswoode, S

    2000-04-01

    Full Text Available -induced seismicity. This control measure has been exercised through limiting the average Energy Release Rate (ERR) to some figure, typically 20 or 30 MJ/m2. Mines have responded by leaving large areas of reef as regional stability pillars. It has been found... of the effect of backfill requires a study of in-stope measurements. Further research in this area will most likely improve correlations between observed and modelled seismicity. This will be the main thrust of the GAP722 project starting in April 2000...

  2. Spatiotemporal organization of energy release events in the quiet solar corona

    Energy Technology Data Exchange (ETDEWEB)

    Uritsky, Vadim M. [Catholic University of America at NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Davila, Joseph M., E-mail: vadim.uritsky@nasa.gov [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States)

    2014-11-01

    Using data from the STEREO and SOHO spacecraft, we show that temporal organization of energy release events in the quiet solar corona is close to random, in contrast to the clustered behavior of flaring times in solar active regions. The locations of the quiet-Sun events follow the meso- and supergranulation pattern of the underling photosphere. Together with earlier reports of the scale-free event size statistics, our findings suggest that quiet solar regions responsible for bulk coronal heating operate in a driven self-organized critical state, possibly involving long-range Alfvénic interactions.

  3. Variation of the energy release rate as a crack approaches and passes through an elastic inclusion

    Science.gov (United States)

    Li, Rongshun; Chudnovsky, A.

    1993-01-01

    The variation of the energy release rate (ERP) at the tip of a crack penetrating an elastic inclusion is analyzed using an approach involving modeling the random array of microcracks or other defects by an elastic inclusion with effective elastic properties. Computations are carried out using a finite element procedure. The eight-noded isoparametric serendipity element with the shift of the midpoint to the quarter-point is used to simulate the singularity at the crack tip, and the crack growth is accommodated by implementing a mesh regeneration technique. The ERP values were calculated for various crack tip positions which simulate the process of the crack approaching and penetrating the inclusion.

  4. Linear free energy correlations for fission product release from the Fukushima-Daiichi nuclear accident.

    Science.gov (United States)

    Abrecht, David G; Schwantes, Jon M

    2015-03-03

    This paper extends the preliminary linear free energy correlations for radionuclide release performed by Schwantes et al., following the Fukushima-Daiichi Nuclear Power Plant accident. Through evaluations of the molar fractionations of radionuclides deposited in the soil relative to modeled radionuclide inventories, we confirm the initial source of the radionuclides to the environment to be from active reactors rather than the spent fuel pool. Linear correlations of the form In χ = −α ((ΔGrxn°(TC))/(RTC)) + β were obtained between the deposited concentrations, and the reduction potentials of the fission product oxide species using multiple reduction schemes to calculate ΔG°rxn (TC). These models allowed an estimate of the upper bound for the reactor temperatures of TC between 2015 and 2060 K, providing insight into the limiting factors to vaporization and release of fission products during the reactor accident. Estimates of the release of medium-lived fission products 90Sr, 121mSn, 147Pm, 144Ce, 152Eu, 154Eu, 155Eu, and 151Sm through atmospheric venting during the first month following the accident were obtained, indicating that large quantities of 90Sr and radioactive lanthanides were likely to remain in the damaged reactor cores.

  5. Effective atomic numbers, electron densities and kinetic energy released in matter of vitamins for photon interaction

    Science.gov (United States)

    Shantappa, A.; Hanagodimath, S. M.

    2014-01-01

    Effective atomic numbers, electron densities of some vitamins (Retinol, Riboflavin, Niacin, Biotin, Folic acid, Cobalamin, Phylloquinone and Flavonoids) composed of C, H, O, N, Co, P and S have been calculated for total and partial photon interactions by the direct method for energy range 1 keV-100 GeV by using WinXCOM and kinetic energy released in matter (Kerma) relative to air is calculated in energy range of 1 keV-20 MeV. Change in effective atomic number and electron density with energy is calculated for all photon interactions. Variation of photon mass attenuation coefficients with energy are shown graphically only for total photon interaction. It is observed that change in mass attenuation coefficient with composition of different chemicals is very large below 100 keV and moderate between 100 keV and 10 MeV and negligible above 10 MeV. Behaviour of vitamins is almost indistinguishable except biotin and cobalamin because of large range of atomic numbers from 1(H) to 16 (S) and 1(H) to 27(Co) respectively. K a value shows a peak due to the photoelectric effect around K-absorption edge of high- Z constituent of compound for biotin and cobalamin.

  6. DEM code-based modeling of energy accumulation and release in structurally heterogeneous rock masses

    Science.gov (United States)

    Lavrikov, S. V.; Revuzhenko, A. F.

    2015-10-01

    Based on discrete element method, the authors model loading of a physical specimen to describe its capacity to accumulate and release elastic energy. The specimen is modeled as a packing of particles with viscoelastic coupling and friction. The external elastic boundary of the packing is represented by particles connected by elastic springs. The latter means introduction of an additional special potential of interaction between the boundary particles, that exercises effect even when there is no direct contact between the particles. On the whole, the model specimen represents an element of a medium capable of accumulation of deformation energy in the form of internal stresses. The data of the numerical modeling of the physical specimen compression and the laboratory testing results show good qualitative consistency.

  7. Vorticity generation by the instantaneous release of energy near a reflective boundary

    Science.gov (United States)

    Moresco, P.; Harris, T. E.; Jodoin, V.

    2014-08-01

    The instantaneous release of energy in a localized area of a gas results in the formation of a low-density region and a series of shock and expansion waves. If this process occurs near a boundary, the shock reflections can interact with the density inhomogeneity, leading to the baroclinic generation of vorticity and the subsequent organization of the flow into several structures, including a vortex ring. By means of numerical simulations we illustrate the qualitative changes that occur in the pressure wave patterns and vorticity distribution as the distance from the area of energy release to the boundary is varied. Those changes are shown to be related to the combined effect of the shock waves that, respectively, initially move away and towards the center of the low-density region. In particular, we describe how for small enough offset distances the shocks internal to the inhomogeneity can make a substantial contribution to the vorticity field, influencing the circulation and characteristics of the resulting flow structures.

  8. Improvement in energy release properties of boron-based propellant by oxidant coating

    Energy Technology Data Exchange (ETDEWEB)

    Liang, Daolun; Liu, Jianzhong, E-mail: jzliu@zju.edu.cn; Chen, Binghong; Zhou, Junhu; Cen, Kefa

    2016-08-20

    Highlights: • NH{sub 4}ClO{sub 4}, KNO{sub 3}, KClO{sub 4} and HMX coated B were used to prepare propellant samples. • FTIR, XRD and SEM were used for the microstructure analysis of the prepared B. • Thermal oxidation and combustion characteristics of the propellants were studied. • HMX coating was the most beneficial to the energy release of the samples. - Abstract: The energy release properties of a propellant can be improved by coating boron (B) particles with oxidants. In the study, B was coated with four different oxidants, namely, NH{sub 4}ClO{sub 4}, KNO{sub 3}, LiClO{sub 4}, and cyclotetramethylenetetranitramine (HMX), and the corresponding propellant samples were prepared. First, the structural and morphological analyses of the pretreated B were carried out. Then, the thermal analysis and laser ignition experiments of the propellant samples were carried out. Coating with NH{sub 4}ClO{sub 4} showed a better performance than mechanical mixing with the same component. Coating with KNO{sub 3} efficiently improved the ignition characteristics of the samples. Coating with LiClO{sub 4} was the most beneficial in reducing the degree of difficulty of B oxidation. Coating with HMX was the most beneficial in the heat release of the samples. The KNO{sub 3}-coated sample had a very high combustion intensity in the beginning, but then it rapidly became weak. Large amounts of sparks were ejected during the combustion of the LiClO{sub 4}-coated sample. The HMX-coated sample had the longest self-sustaining combustion time (4332 ms) and the highest average combustion temperature (1163.92 °C).

  9. Soft computing analysis of the possible correlation between temporal and energy release patterns in seismic activity

    Science.gov (United States)

    Konstantaras, Anthony; Katsifarakis, Emmanouil; Artzouxaltzis, Xristos; Makris, John; Vallianatos, Filippos; Varley, Martin

    2010-05-01

    This paper is a preliminary investigation of the possible correlation of temporal and energy release patterns of seismic activity involving the preparation processes of consecutive sizeable seismic events [1,2]. The background idea is that during periods of low-level seismic activity, stress processes in the crust accumulate energy at the seismogenic area whilst larger seismic events act as a decongesting mechanism releasing considerable energy [3,4]. A dynamic algorithm is being developed aiming to identify and cluster pre- and post- seismic events to the main earthquake following on research carried out by Zubkov [5] and Dobrovolsky [6,7]. This clustering technique along with energy release equations dependent on Richter's scale [8,9] allow for an estimate to be drawn regarding the amount of the energy being released by the seismic sequence. The above approach is being implemented as a monitoring tool to investigate the behaviour of the underlying energy management system by introducing this information to various neural [10,11] and soft computing models [1,12,13,14]. The incorporation of intelligent systems aims towards the detection and simulation of the possible relationship between energy release patterns and time-intervals among consecutive sizeable earthquakes [1,15]. Anticipated successful training of the imported intelligent systems may result in a real-time, on-line processing methodology [1,16] capable to dynamically approximate the time-interval between the latest and the next forthcoming sizeable seismic event by monitoring the energy release process in a specific seismogenic area. Indexing terms: pattern recognition, long-term earthquake precursors, neural networks, soft computing, earthquake occurrence intervals References [1] Konstantaras A., Vallianatos F., Varley M.R. and Makris J. P.: ‘Soft computing modelling of seismicity in the southern Hellenic arc', IEEE Geoscience and Remote Sensing Letters, vol. 5 (3), pp. 323-327, 2008 [2] Eneva M. and

  10. Stochastic Fermi Energization of Coronal Plasma during Explosive Magnetic Energy Release

    Energy Technology Data Exchange (ETDEWEB)

    Pisokas, Theophilos; Vlahos, Loukas; Isliker, Heinz; Tsiolis, Vassilis [Department of Physics, Aristotle University of Thessaloniki GR-52124 Thessaloniki (Greece); Anastasiadis, Anastasios [Institute for Astronomy, Astrophysics, Space Applications and Remote Sensing, National Observatory of Athens GR-15236 Penteli (Greece)

    2017-02-01

    The aim of this study is to analyze the interaction of charged particles (ions and electrons) with randomly formed particle scatterers (e.g., large-scale local “magnetic fluctuations” or “coherent magnetic irregularities”) using the setup proposed initially by Fermi. These scatterers are formed by the explosive magnetic energy release and propagate with the Alfvén speed along the irregular magnetic fields. They are large-scale local fluctuations ( δB / B ≈ 1) randomly distributed inside the unstable magnetic topology and will here be called Alfvénic Scatterers (AS). We constructed a 3D grid on which a small fraction of randomly chosen grid points are acting as AS. In particular, we study how a large number of test particles evolves inside a collection of AS, analyzing the evolution of their energy distribution and their escape-time distribution. We use a well-established method to estimate the transport coefficients directly from the trajectories of the particles. Using the estimated transport coefficients and solving the Fokker–Planck equation numerically, we can recover the energy distribution of the particles. We have shown that the stochastic Fermi energization of mildly relativistic and relativistic plasma can heat and accelerate the tail of the ambient particle distribution as predicted by Parker and Tidman and Ramaty. The temperature of the hot plasma and the tail of the energetic particles depend on the mean free path ( λ {sub sc}) of the particles between the scatterers inside the energization volume.

  11. Preliminary fission product energy release measurements for thermal neutron fission of 235U

    International Nuclear Information System (INIS)

    Dickens, J.K.; Love, T.A.; McConnell, J.W.; Emery, J.F.; Peelle, R.W.

    1976-03-01

    An experimental system to measure time-dependent spectra of β and γ rays from fission-product production by thermal neutron fission of 235 U is described, and for each component (β and γ) the system has been tested with a pilot data-accumulation run. Data reduction techniques are described and test results given. Gamma-ray spectra are compared with calculations using ENDF/B-IV data files. Both β- and γ-ray spectra were integrated to give total yields and total energy-release results for times after fission between 3 and 14400 sec. These preliminary integral data are compared with previous measurements and with integral calculations using ENDF/B-IV data files

  12. An analysis methodology for hot leg break mass and energy release

    International Nuclear Information System (INIS)

    Song, Jin Ho; Kwon, Young Min; Kim, Taek Mo; Chung, Hae Yong; Lee, Sang Jong

    1996-07-01

    An analysis methodology for the hot leg break mass and energy release is developed. For the blowdown period a modified CEFLASH-4A analysis is suggested. For the post-blowdown period a new computer model named COMET is developed. Differently from previous post-blowdown analysis model FLOOD3, COMET is capable of analyzing both cold leg and hot leg break cases. The cold leg break model is essentially same as that of FLOOD3 with some improvements. The analysis results by the newly proposed hot leg break model in the COMET is in the same trend as those observed in scaled-down integral experiment. And the analyses results for the UCN 3 and 4 by COMET are qualitatively and quantitatively in good agreement with those predicted by best-estimate analysis by using RELAP5/MOD3. Therefore, the COMET code is validated and can be used for the licensing analysis. 6 tabs., 82 figs., 9 refs. (Author)

  13. Detection of cold gas releases in space via low energy neutral atom imaging

    International Nuclear Information System (INIS)

    McComas, D.J.; Funsten, H.O.; Moore, K.R.; Scime, E.E.; Thomsen, M.F.

    1993-01-01

    Low energy neutral atoms (LENAs) are produced in space plasmas by charge exchange between the ambient magnetospheric plasma ions and cold neutral atoms. Under normal conditions these cold neutrals come from the terrestrial geocorona, a shroud of few-eV hydrogen atoms surrounding the Earth. As a consequence of this charge exchange, it has become possible to remotely image many regions of the magnetosphere for the first time utilizing recently developed LENA imaging technology. In addition to the natural hydrogen geocorona, conventional explosions and maneuvering thruster firings can also introduce large amounts of cold gas into the space environment. In this paper the authors examine whether such potentially clandestine activities could also be remotely observed for the first time via LENA imaging. First, they examine the fluxes of LENAs produced in the space environment from a conventional explosion. Then they review the present state of the art in the emerging field of LENA detection and imaging. Recent work has shown that LENAs can be imaged by first converting the neutrals to ions with ultra-thin (10s of angstrom) foils and then electrostatically analyzing these newly created ions to reject the large (> 10 10 cm -2 s -1 ) UV background to which the low energy detectors are sensitive. They conclude that the sensitivities for present LENA imager designs may be just adequate for detecting some man-made releases. With additional improvements in LENA detection capabilities, this technique could become an important new method for monitoring for conventional explosions, as well as other man-made neutral releases, in the space environment

  14. Adhesive-Bonded Composite Joint Analysis with Delaminated Surface Ply Using Strain-Energy Release Rate

    Science.gov (United States)

    Chadegani, Alireza; Yang, Chihdar; Smeltzer, Stanley S. III

    2012-01-01

    This paper presents an analytical model to determine the strain energy release rate due to an interlaminar crack of the surface ply in adhesively bonded composite joints subjected to axial tension. Single-lap shear-joint standard test specimen geometry with thick bondline is followed for model development. The field equations are formulated by using the first-order shear-deformation theory in laminated plates together with kinematics relations and force equilibrium conditions. The stress distributions for the adherends and adhesive are determined after the appropriate boundary and loading conditions are applied and the equations for the field displacements are solved. The system of second-order differential equations is solved to using the symbolic computation tool Maple 9.52 to provide displacements fields. The equivalent forces at the tip of the prescribed interlaminar crack are obtained based on interlaminar stress distributions. The strain energy release rate of the crack is then determined by using the crack closure method. Finite element analyses using the J integral as well as the crack closure method are performed to verify the developed analytical model. It has been shown that the results using the analytical method correlate well with the results from the finite element analyses. An attempt is made to predict the failure loads of the joints based on limited test data from the literature. The effectiveness of the inclusion of bondline thickness is justified when compared with the results obtained from the previous model in which a thin bondline and uniform adhesive stresses through the bondline thickness are assumed.

  15. Improving containment mass and energy releases for CONTEMPT-LT/028 TU with RELAP5/MOD3

    International Nuclear Information System (INIS)

    DaSilva, H.C.; Choe, W.G.

    1996-01-01

    In order to obtain boundary conditions for RELAP5/MOD3 best estimate (BE) large break (LB) loss-of-coolant accident (LOCA) calculations, it is necessary to utilize a separate containment analysis code CONTEMPT-LT/028 TU, which in turn accepts mass and energy releases from the RELAP5/MOD3 calculation. When these boundary conditions are obtained, they are observed to be significantly lower than those reported in FSAR containment analyses. This motivates the present study, where RELAP5/MOD3 mass and energy releases are generated using the same assumptions listed in the FSAR containment calculations. Then CONTEMPT-LT/028 TU pressures and temperatures calculated with both sets of mass and energy releases are compared. It is seen that those obtained with the RELAP5/MOD3 input are still significantly lower, indicating a level of conservatism in the FSAR mass and energy releases that is even above that explicitly listed and also incorporated into the RELAP5/MOD3 calculation. An important conclusion from this finding is that Environmental Qualification (EQ) issues requiring containment re-analyses are likely to be easily resolved if new mass and energy releases are calculated with state-of-the-art LOCA codes modeling the entire reactor coolant system, even when conservative assumptions are incorporated

  16. Effects on LOCA mass and energy release of the SIT Fluidic device for SKN 3 and 4

    Energy Technology Data Exchange (ETDEWEB)

    Song, Jeung Hyo; Kim, Tae Yoon; Choi, Han Rim; Choi, Chul Jin; Seo, Jong Tae [Korea Power Engineering Company, Daejon (Korea, Republic of)

    2003-07-01

    A fluidic device is employed for the control of safety injection tank flow during a large break loss of coolant accident in Shin Kori Nuclear power plant Unit 3 and 4. It is installed in the safety injection tank and provides two stages of safety injection tank flow injection, initially high flow injection and then low flow injection after the reactor vessel downcomer annulus full. This allows a more effective use of safety injection tank water inventory during a loss of coolant accident. However, the fluidic device may have an adverse impact on the mass and energy release during the accident. That is, the steam mass and energy release will be increased by a considerable amount because the safety injection tank low flow injection via fluidic device is not credited to condense the steam flows through intact cold legs. The increased mass and energy releases have an impact on the peak pressure and temperature of the containment. This effect of the fluidic device is analyzed on the mass and energy release and the peak pressure and temperature of the containment. The calculation has been done using the CEFLASH-4A, the FLOOD3 with some modifications for the fluidic device and the CONTEMPT-LT code. The results show that the mass and energy release and the peak pressure and temperature were considerably increased when compared with the case without the fluidic device. However, the results satisfy the required design margin.

  17. Effects on LOCA mass and energy release of the SIT Fluidic device for SKN 3 and 4

    International Nuclear Information System (INIS)

    Song, Jeung Hyo; Kim, Tae Yoon; Choi, Han Rim; Choi, Chul Jin; Seo, Jong Tae

    2003-01-01

    A fluidic device is employed for the control of safety injection tank flow during a large break loss of coolant accident in Shin Kori Nuclear power plant Unit 3 and 4. It is installed in the safety injection tank and provides two stages of safety injection tank flow injection, initially high flow injection and then low flow injection after the reactor vessel downcomer annulus full. This allows a more effective use of safety injection tank water inventory during a loss of coolant accident. However, the fluidic device may have an adverse impact on the mass and energy release during the accident. That is, the steam mass and energy release will be increased by a considerable amount because the safety injection tank low flow injection via fluidic device is not credited to condense the steam flows through intact cold legs. The increased mass and energy releases have an impact on the peak pressure and temperature of the containment. This effect of the fluidic device is analyzed on the mass and energy release and the peak pressure and temperature of the containment. The calculation has been done using the CEFLASH-4A, the FLOOD3 with some modifications for the fluidic device and the CONTEMPT-LT code. The results show that the mass and energy release and the peak pressure and temperature were considerably increased when compared with the case without the fluidic device. However, the results satisfy the required design margin

  18. Spontaneous deregulation

    NARCIS (Netherlands)

    Edelman, Benjamin; Geradin, Damien

    Platform businesses such as Airbnb and Uber have risen to success partly by sidestepping laws and regulations that encumber their traditional competitors. Such rule flouting is what the authors call “spontaneous private deregulation,” and it’s happening in a growing number of industries. The authors

  19. Precise calculation of neutron-capture reactions contribution in energy release for different types of VVER-1000 fuel assemblies

    Science.gov (United States)

    Tikhomirov, Georgy; Bahdanovich, Rynat; Pham, Phu

    2017-09-01

    Precise calculation of energy release in a nuclear reactor is necessary to obtain the correct spatial power distribution and predict characteristics of burned nuclear fuel. In this work, previously developed method for calculation neutron-capture reactions - capture component - contribution in effective energy release in a fuel core of nuclear reactor is discussed. The method was improved and implemented to the different models of VVER-1000 reactor developed for MCU 5 and MCNP 4 computer codes. Different models of equivalent cell and fuel assembly in the beginning of fuel cycle were calculated. These models differ by the geometry, fuel enrichment and presence of burnable absorbers. It is shown, that capture component depends on fuel enrichment and presence of burnable absorbers. Its value varies for different types of hot fuel assemblies from 3.35% to 3.85% of effective energy release. Average capture component contribution in effective energy release for typical serial fresh fuel of VVER-1000 is 3.5%, which is 7 MeV/fission. The method will be used in future to estimate the dependency of capture energy on fuel density, burn-up, etc.

  20. Precise calculation of neutron-capture reactions contribution in energy release for different types of VVER-1000 fuel assemblies

    Directory of Open Access Journals (Sweden)

    Tikhomirov Georgy

    2017-01-01

    Full Text Available Precise calculation of energy release in a nuclear reactor is necessary to obtain the correct spatial power distribution and predict characteristics of burned nuclear fuel. In this work, previously developed method for calculation neutron-capture reactions – capture component – contribution in effective energy release in a fuel core of nuclear reactor is discussed. The method was improved and implemented to the different models of VVER-1000 reactor developed for MCU 5 and MCNP 4 computer codes. Different models of equivalent cell and fuel assembly in the beginning of fuel cycle were calculated. These models differ by the geometry, fuel enrichment and presence of burnable absorbers. It is shown, that capture component depends on fuel enrichment and presence of burnable absorbers. Its value varies for different types of hot fuel assemblies from 3.35% to 3.85% of effective energy release. Average capture component contribution in effective energy release for typical serial fresh fuel of VVER-1000 is 3.5%, which is 7 MeV/fission. The method will be used in future to estimate the dependency of capture energy on fuel density, burn-up, etc.

  1. Spontaneous release of epiretinal membrane in a young weight-lifting athlete by presumed central rupture and centrifugal pull

    Directory of Open Access Journals (Sweden)

    Mansour AM

    2014-11-01

    Full Text Available Ahmad M Mansour,1,2 Hana A Mansour,3 J Fernando Arevalo4,5 1Department of Ophthalmology, Rafic Hariri University Hospital, Beirut, Lebanon; 2Department of Ophthalmology, American University of Beirut, Beirut, Lebanon; 3Department of Biology, American University of Beirut, Beirut, Lebanon; 4Retina Department, The King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia; 5Retina Department, Wilmer Eye Institute, The Johns Hopkins University, Baltimore, MD, USA Abstract: This patient presented for surgery at the age of 32 years, 14 months after his initial complaint of metamorphopsia and visual loss in the right eye. Past tests demonstrated a whitish epiretinal membrane (ERM with translucent stress lines over a thickened macula. Visual acuity was found on last presentation to be normal with minimal alteration on Amsler grid testing. A torn ERM was found in the center with left-over ERM temporally and rolled-over ERM nasally at the site of the epicenter with no posterior vitreous detachment. Visual recovery occurred gradually over several days 2 months prior to presentation apparently following heavy weight-lifting with a sensation of severe eye pressure. Sequential funduscopy and optical coherence tomography scans demonstrated the peeling of an ERM accompanied by normalization of foveal thickness. Valsalva maneuver had put excessive tension on ERM which tore in its center at the weakest line with gradual contraction of the ERM away from the fovea towards the peripapillary area. This is a new mechanism of self-separation of ERM induced by Valsalva. ERM in young subjects is subject to rupture and subsequent separation by tangential traction. There are three mechanisms for spontaneous separation of ERM: 1 posterior vitreous detachment with pulling of ERM by detaching vitreous (most common in adults; 2 the contracting forces of the immature ERM become stronger than its adhesions to the retina resulting in slow tangential traction on the

  2. Dark energy as consequence of release of cosmological nuclear binding-energy, and its further extension towards a new theory of inflation

    International Nuclear Information System (INIS)

    Gupta, R.C.; Pradhan, Anirudh; Gupta, Sushant

    2012-01-01

    Comparatively recent observations on Type-Ia supernovae and low density (Um = 0.3) measurement of matter including dark matter suggest that the present day universe consists mainly of repulsive-gravity type 'exotic matter' with negative-pressure often said 'dark energy' (Ux = O7). But the nature of dark energy is mysterious and its puzzling questions, such as why, how, where and when about the dark energy, are intriguing. In the present paper the authors attempt to answer these questions while making an effort to reveal the genesis of dark energy, and suggest that the cosmological nuclear binding energy liberated during primordial nucleo-synthesis remains trapped dormant for a long time and then is released free which manifests itself as dark energy in the universe. It is also explained why for dark energy the parameter w = -2/3. Noting that w = 1 for stiff matter and w = 1/3 for radiation; w = -2/3 is for dark energy because '- 1' is due to 'deficiency of stiff- nuclear-matter' and that this binding energy is ultimately released as 'radiation' contributing '+ 1/3', making w = -1+ 1/3 = -2/3. When dark energy is released free at Z = 80, w = -2/3. But as on present day at Z = 0 when radiation strength has diminished to ä ? 0, the parameter w = -1 + ä 1/3 = -1. This, thus almost solves the dark- energy mystery of negative pressure and repulsive-gravity. The proposed theory makes several estimates/predictions which agree reasonably well with the astrophysical constraints and observations. Though there are many candidate-theories, the proposed model of this paper presents an entirely new approach (cosmological nuclear energy) as a possible candidate for dark energy. The secret of acceleration of big-universe is hidden in the small-nucleus. (author)

  3. Two-stage Energy Release Process of a Confined Flare with Double HXR Peaks

    Science.gov (United States)

    Ning, Hao; Chen, Yao; Wu, Zhao; Su, Yang; Tian, Hui; Li, Gang; Du, Guohui; Song, Hongqiang

    2018-02-01

    A complete understanding of the onset and subsequent evolution of confined flares has not been achieved. Earlier studies mainly analyzed disk events so as to reveal their magnetic topology and the cause of confinement. In this study, taking advantage of a tandem of instruments working at different wavelengths of X-rays, EUVs, and microwaves, we present dynamic details about a confined flare observed on the northwestern limb of the solar disk on 2016 July 24. The entire dynamic evolutionary process starting from its onset is consistent with a loop–loop interaction scenario. The X-ray profiles manifest an intriguing double-peak feature. From the spectral fitting, it has been found that the first peak is nonthermally dominated, while the second peak is mostly multithermal with a hot (∼10 MK) and a super-hot (∼30 MK) component. This double-peak feature is unique in that the two peaks are clearly separated by 4 minutes, and the second peak reaches up to 25–50 keV in addition, at energy bands above 3 keV, the X-ray fluxes decline significantly between the two peaks. This, together with other available imaging and spectral data, manifest a two-stage energy release process. A comprehensive analysis is carried out to investigate the nature of this two-stage process. We conclude that the second stage with the hot and super-hot sources mainly involves direct heating through a loop–loop reconnection at a relatively high altitude in the corona. The uniqueness of the event characteristics and the complete dataset make the study a nice addition to present literature on solar flares.

  4. The statistical analysis of energy release in small-scale coronal structures

    Science.gov (United States)

    Ulyanov, Artyom; Kuzin, Sergey; Bogachev, Sergey

    We present the results of statistical analysis of impulsive flare-like brightenings, which numerously occur in the quiet regions of solar corona. For our study, we utilized high-cadence observations performed with two EUV-telescopes - TESIS/Coronas-Photon and AIA/SDO. In total, we processed 6 sequences of images, registered throughout the period between 2009 and 2013, covering the rising phase of the 24th solar cycle. Based on high-speed DEM estimation method, we developed a new technique to evaluate the main parameters of detected events (geometrical sizes, duration, temperature and thermal energy). We then obtained the statistical distributions of these parameters and examined their variations depending on the level of solar activity. The results imply that near the minimum of the solar cycle the energy release in quiet corona is mainly provided by small-scale events (nanoflares), whereas larger events (microflares) prevail on the peak of activity. Furthermore, we investigated the coronal conditions that had specified the formation and triggering of registered flares. By means of photospheric magnetograms obtained with MDI/SoHO and HMI/SDO instruments, we examined the topology of local magnetic fields at different stages: the pre-flare phase, the peak of intensity and the ending phase. To do so, we introduced a number of topological parameters including the total magnetic flux, the distance between magnetic sources and their mutual arrangement. The found correlation between the change of these parameters and the formation of flares may offer an important tool for application of flare forecasting.

  5. Phase changing nanocomposites for low temperature thermal energy storage and release

    Directory of Open Access Journals (Sweden)

    A. Dorigato

    2017-09-01

    Full Text Available The aim of this paper is to develop new elastomeric phase change materials (PCM for the thermal energy storage/release below room temperature. In particular, poly(cyclooctene (PCO/paraffin blends filled with various concentrations of carbon nanotubes (CNTs, were prepared by a melt compounding process. The microstructural, thermo-mechanical and electrical properties of the resulting materials were investigated. The microstructure of these materials was characterized by the presence of paraffin domains inside the PCO, and CNTs were located only inside the paraffin domains in forms of aggregated clusters. DSC tests evidenced the existence of two distinct crystallization peaks at –10 and at 6 °C, respectively associated to the paraffin and the PCO phases, indicating that both the polymeric constituents are thermally active below room temperature. Moreover, CNT addition did not substantially alter the melting/crystallization properties of the material. Noticeable improvements of the mechanical properties and of the electrical conductivity with respect to the neat PCO/paraffin blend could be obtained upon CNT addition, and also thermal conductivity/diffusivity values were considerably enhanced above the percolation threshold. Finite element modeling demonstrated the efficacy of the prepared nanocomposites for applications in the thermal range from –30 to 6 °C.

  6. Spontaneous release of fluoride during the dioxygenolytic cleavage of 5-fluorosalicylate by the salicylate 1,2-dioxygenase from Pseudaminobacter salicylatoxidans BN12.

    Science.gov (United States)

    Eppinger, Erik; Bürger, Sibylle; Stolz, Andreas

    2016-01-01

    The alpha-Proteobacterium Pseudaminobacter salicylatoxidans BN12 forms a peculiar gentisate 1,2-dioxygenase (SDO) that oxidatively cleaves gentisate (2,5-dihydroxybenzoate) and additionally 1-hydroxy-2-naphthoate, salicylate and various amino-, chloro-, fluoro-, hydroxy- and methylsalicylates. In the present study, the conversion of 5-fluorosalicylate by this enzyme was analysed using various analytical techniques. Spectrophotometric assays showed that the conversion of 5-fluorosalicylate by the purified enzyme resulted in the formation of a new unstable intermediate showing an absorbance maximum at λmax = 292 nm. The analysis of the enzymatic reaction by HPLC showed that two main products with absorbance maxima at λmax = 292-296 nm were formed from 5-fluorosalicylate. The same two products (although in different relative proportions) were also formed when the SDO transformed 5-chlorosalicylate or when a purified 5-nitrosalicylate 1,2-dioxygenase from Bradyrhizobium sp. JS329 oxidized 5-nitrosalicylate. A whole cell system with recombinant Escherichia coli cells overexpressing the SDO activity was established in order to produce larger amounts of the reaction products. The reaction products were subsequently identified by (1)H-NMR and mass spectrometry as stereoisomers of 2-oxo-3-(5-oxofuran-2-ylidine)propanoic acid. The release of fluoride in the course of the dioxygenolytic cleavage reaction was confirmed by ion-chromatography and (19)F-NMR. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  7. Dose-related effects of lauric acid on antropyloroduodenal motility, gastrointestinal hormone release, appetite, and energy intake in healthy men

    NARCIS (Netherlands)

    Little, Tanya J.; Feltrin, Kate L.; Horowitz, Michael; Smout, Andre J. P. M.; Rades, Thomas; Meyer, James H.; Pilichiewicz, Amelia N.; Wishart, Judith; Feinle-Bisset, Christine

    2005-01-01

    We recently reported that intraduodenal infusion of lauric acid (C12) (0.375 kcal/min, 106 mM) stimulates isolated pyloric pressure waves (IPPWs), inhibits antral and duodenal pressure waves (PWs), stimulates release of cholecystokinin (CCK) and glucagon-like peptide-1 (GLP-1), and suppresses energy

  8. Iron oxide/aluminum/graphene energetic nanocomposites synthesized by atomic layer deposition: Enhanced energy release and reduced electrostatic ignition hazard

    Science.gov (United States)

    Yan, Ning; Qin, Lijun; Hao, Haixia; Hui, Longfei; Zhao, Fengqi; Feng, Hao

    2017-06-01

    Nanocomposites consisting of iron oxide (Fe2O3) and nano-sized aluminum (Al), possessing outstanding exothermic redox reaction characteristics, are highly promising nanothermite materials. However, the reactant diffusion inhibited in the solid state system makes the fast and complete energy release very challenging. In this work, Al nanoparticles anchored on graphene oxide (GO/Al) was initially prepared by a solution assembly approach. Fe2O3 was deposited on GO/Al substrates by atomic layer deposition (ALD). Simultaneously thermal reduction of GO occurs, resulting in rGO/Al@Fe2O3 energetic composites. Differential scanning calorimetry (DSC) analysis reveals that rGO/Al@Fe2O3 composite containing 4.8 wt% of rGO exhibits a 50% increase of the energy release compared to the Al@Fe2O3 nanothermite synthesized by ALD, and an increase of about 130% compared to a random mixture of rGO/Al/Fe2O3 nanoparticles. The enhanced energy release of rGO/Al@Fe2O3 is attributed to the improved spatial distribution as well as the increased interfacial intimacy between the oxidizer and the fuel. Moreover, the rGO/Al@Fe2O3 composite with an rGO content of 9.6 wt% exhibits significantly reduced electrostatic discharge sensitivity. These findings may inspire potential pathways for engineering energetic nanocomposites with enhanced energy release and improved safety characteristics.

  9. The Temperature Condition of the Plate with Temperature-Dependent Thermal Conductivity and Energy Release

    OpenAIRE

    V. S. Zarubin; A. V. Kotovich; G. N. Kuvyrkin

    2016-01-01

    The temperature state of a solid body, in addition to the conditions of its heat exchange with the environment, can greatly depend on the heat release (or heat absorption) processes within the body volume. Among the possible causes of these processes should be noted such as a power release in the fuel elements of nuclear reactors, exothermic or endothermic chemical reactions in the solid body material, which respectively involve heat release or absorbtion, heat transfer of a part of the elect...

  10. Iron oxide/aluminum/graphene energetic nanocomposites synthesized by atomic layer deposition: Enhanced energy release and reduced electrostatic ignition hazard

    Energy Technology Data Exchange (ETDEWEB)

    Yan, Ning; Qin, Lijun [Laboratory of Material Surface Engineering and Nanofabrication, Xi’an Modern Chemistry Research Institute, Shaanxi (China); Science and Technology on Combustion and Explosion Laboratory, Xi’an Modern Chemistry Research Institute, Shaanxi (China); Hao, Haixia [Science and Technology on Combustion and Explosion Laboratory, Xi’an Modern Chemistry Research Institute, Shaanxi (China); Hui, Longfei [Laboratory of Material Surface Engineering and Nanofabrication, Xi’an Modern Chemistry Research Institute, Shaanxi (China); Science and Technology on Combustion and Explosion Laboratory, Xi’an Modern Chemistry Research Institute, Shaanxi (China); Zhao, Fengqi [Science and Technology on Combustion and Explosion Laboratory, Xi’an Modern Chemistry Research Institute, Shaanxi (China); Feng, Hao, E-mail: fenghao98@hotmail.com [Laboratory of Material Surface Engineering and Nanofabrication, Xi’an Modern Chemistry Research Institute, Shaanxi (China); State Key Laboratory of Fluorine and Nitrogen Chemicals, Xi’an Modern Chemistry Research Institute, Shaanxi (China)

    2017-06-30

    Highlights: • Energetic rGO/Al@Fe{sub 2}O{sub 3}nanocompositeswerefabricatedbyatomiclayerdepositionapproach. • A novel Al@Fe{sub 2}O{sub 3} unit featuring core-shell structure was decorated on the graphene nanosheet. • RGO/Al@Fe{sub 2}O{sub 3} nanocomposite exhibits superior energy release and reduced electrostatic ignition hazard. - Abstract: Nanocomposites consisting of iron oxide (Fe{sub 2}O{sub 3}) and nano-sized aluminum (Al), possessing outstanding exothermic redox reaction characteristics, are highly promising nanothermite materials. However, the reactant diffusion inhibited in the solid state system makes the fast and complete energy release very challenging. In this work, Al nanoparticles anchored on graphene oxide (GO/Al) was initially prepared by a solution assembly approach. Fe{sub 2}O{sub 3} was deposited on GO/Al substrates by atomic layer deposition (ALD). Simultaneously thermal reduction of GO occurs, resulting in rGO/Al@Fe{sub 2}O{sub 3} energetic composites. Differential scanning calorimetry (DSC) analysis reveals that rGO/Al@Fe{sub 2}O{sub 3} composite containing 4.8 wt% of rGO exhibits a 50% increase of the energy release compared to the Al@Fe{sub 2}O{sub 3} nanothermite synthesized by ALD, and an increase of about 130% compared to a random mixture of rGO/Al/Fe{sub 2}O{sub 3} nanoparticles. The enhanced energy release of rGO/Al@Fe{sub 2}O{sub 3} is attributed to the improved spatial distribution as well as the increased interfacial intimacy between the oxidizer and the fuel. Moreover, the rGO/Al@Fe{sub 2}O{sub 3} composite with an rGO content of 9.6 wt% exhibits significantly reduced electrostatic discharge sensitivity. These findings may inspire potential pathways for engineering energetic nanocomposites with enhanced energy release and improved safety characteristics.

  11. Iron oxide/aluminum/graphene energetic nanocomposites synthesized by atomic layer deposition: Enhanced energy release and reduced electrostatic ignition hazard

    International Nuclear Information System (INIS)

    Yan, Ning; Qin, Lijun; Hao, Haixia; Hui, Longfei; Zhao, Fengqi; Feng, Hao

    2017-01-01

    Highlights: • Energetic rGO/Al@Fe 2 O 3 nanocompositeswerefabricatedbyatomiclayerdepositionapproach. • A novel Al@Fe 2 O 3 unit featuring core-shell structure was decorated on the graphene nanosheet. • RGO/Al@Fe 2 O 3 nanocomposite exhibits superior energy release and reduced electrostatic ignition hazard. - Abstract: Nanocomposites consisting of iron oxide (Fe 2 O 3 ) and nano-sized aluminum (Al), possessing outstanding exothermic redox reaction characteristics, are highly promising nanothermite materials. However, the reactant diffusion inhibited in the solid state system makes the fast and complete energy release very challenging. In this work, Al nanoparticles anchored on graphene oxide (GO/Al) was initially prepared by a solution assembly approach. Fe 2 O 3 was deposited on GO/Al substrates by atomic layer deposition (ALD). Simultaneously thermal reduction of GO occurs, resulting in rGO/Al@Fe 2 O 3 energetic composites. Differential scanning calorimetry (DSC) analysis reveals that rGO/Al@Fe 2 O 3 composite containing 4.8 wt% of rGO exhibits a 50% increase of the energy release compared to the Al@Fe 2 O 3 nanothermite synthesized by ALD, and an increase of about 130% compared to a random mixture of rGO/Al/Fe 2 O 3 nanoparticles. The enhanced energy release of rGO/Al@Fe 2 O 3 is attributed to the improved spatial distribution as well as the increased interfacial intimacy between the oxidizer and the fuel. Moreover, the rGO/Al@Fe 2 O 3 composite with an rGO content of 9.6 wt% exhibits significantly reduced electrostatic discharge sensitivity. These findings may inspire potential pathways for engineering energetic nanocomposites with enhanced energy release and improved safety characteristics.

  12. A method for measurements of neutral fragments kinetic energies released to a specific dissociation threshold: optical translational spectroscopy

    International Nuclear Information System (INIS)

    Roney, A.; Frigon, C.; Larzilliere, M.

    1999-01-01

    The optical translational spectroscopy technique, based on the principles of fast ion beam laser spectroscopy (FIBLAS) and translational spectroscopy, allows the kinetic energies study of neutral fragments released through free dissociation of a neutral molecule. This method presents interesting features such as near-threshold energy measurements and selection of a specific dissociation limit. The fragments resulting from free dissociation (not induced) of neutral molecules, produced by charge exchange processes with a fast ion beam, are probed by laser radiation. Monitoring of the laser-induced fluorescence allows high-resolution spectra due to the kinematic compression of the velocity spread. Measurements of kinetic energies released to the second limit of dissociation H(1s) + H(2l) of H 2 are put forth and compared with those obtained by means of off-axis translational spectroscopy

  13. Glucose Fluctuations are Not Modulated by the Proportion of Calories from Macronutrients or Spontaneous Total Energy Expenditure in Adults with Cystic Fibrosis.

    Science.gov (United States)

    Ziai, Sophie; Coriati, Adèle; St-Pierre, David; Chabot, Katherine; Desjardins, Katherine; Leroux, Catherine; Richter, Martin V; Rabasa-Lhoret, Rémi

    2016-10-01

    To determine the modifiable factors affecting glucose variability in people with cystic fibrosis (CF). CF-related diabetes (CFRD) is the most common complication of CF, and its presence increases morbidity and mortality in patients. Patients with CF (with and without CFRD) have potentially harmful glucose fluctuations and glucose excursions when compared to healthy adults. Carbohydrate intake and exercise have been shown to affect glycemia. Therefore, our hypothesis was that the proportion of energy from carbohydrates and total energy expenditure (TEE) would influence glucose fluctuations in adults with CF. A cross-sectional study involved 36 patients with CF, in whom continuous glucose monitoring systems were installed. Glucose fluctuations were then quantified using 3 indexes: mean amplitude of glucose excursions, standard deviation and coefficient of variation. Patients filled out a 3-day food diary to quantify energy intake and the proportions of calories from carbohydrates, fats and proteins, and they wore Sensewear Armbands to estimate spontaneous TEE and footsteps walked. Glucose tolerance status was determined using oral glucose tolerance tests. Patients with CF with normal and impaired glucose tolerance had fewer glucose fluctuations than patients with CFRD (p0.05). TEE and the proportion of energy from carbohydrates did not affect glucose fluctuations in adults with CF. Copyright © 2016 Canadian Diabetes Association. Published by Elsevier Inc. All rights reserved.

  14. Protocol for development of authorized release limits for concrete at U.S. Department of Energy sites

    International Nuclear Information System (INIS)

    Arnish, J.; Kamboj, S.; Chen, S.-Y.; Parker, F. L.; Smith, A. M.; Meservey, R. H.; Tripp, J. L.

    2000-01-01

    The purpose of this protocol is to assist US Department of Energy (DOE) sites in releasing concrete for reuse. Current regulations allow the sites to release surface-contaminated materials if their radioactivity falls below certain levels and to possibly release materials with volumetric contamination or higher levels of surface contamination on a case-by-case basis. In all cases, an ALARA (as low as reasonably achievable) analysis that evaluates the risks of releasing volumetrically contaminated concrete or concrete with higher levels of surface contamination is required as a basis for proposing and setting new release limits that allow for reuse of the concrete material. To evaluate the dose impacts of reusing radioactively contaminated material, the measured radiation levels (pCi/g or disintegrations per minute [dpm]/100 cm 2 ) must be converted to the estimated dose (mrem/yr) that would be received by affected individuals. The dose depends on the amounts and types of isotopes present and the time, distance, and method of exposure (e.g., inhalation or external exposure). For each disposition alternative, the protocol provides a systematic method to evaluate the impact of the dose on the affected individuals. The cost impacts of reusing concrete also need to be evaluated. They too depend on the disposition alternative and the extent and type of contamination. The protocol provides a method to perform a detailed analysis of these factors and evaluate the dose and cost impacts for various disposition alternatives. Once the dose and cost impacts of the various alternatives have been estimated, the protocol outlines the steps required to propose new release standards that allow release and reuse of the concrete material

  15. Energy and greenhouse gas profile of the Nouvelle Aquitaine region. Release 2017

    International Nuclear Information System (INIS)

    Rousset, Alain; Poitevin, Lionel; Loeb, Amandine; Philippot, Herve; Rebouillat, Lea; Jacquelin, Antoine

    2017-06-01

    This publication first proposes graphs and comments characterising final energy consumption of the Nouvelle Aquitaine region: regional situation in 2015 (analysis per sector and per energy), primary resources, social-economic analysis (energy bill, level of energy poverty, burden due to old housing and commuting for households), evolution of energy consumption between 2005 and 2015 (per sector, per source of energy, evolution of energy intensity and of the energy bill). The next part addresses greenhouse gas emissions: regional situation in 2015 (distribution in terms of emission type and per gas), evolutions between 1990 and 2015, evolutions per sector. The third part addresses renewable energies: regional situation for the different types of renewable energy, comparison with final energy consumption, comparison with national data, production evolutions, focus per sector (wood and wood by-products, heat pumps in the housing sector, urban waste valorisation units, biogas valorisation, bio-fuels, wind energy, hydroelectricity, solar photovoltaic). The last part recalls national objectives related to energy, to greenhouse gas emissions for France and for the region, in relationship with the law on energy transition and for a green growth

  16. Large diameter permanent-magnets-expanded plasma source for spontaneous generation of low-energy ion beam.

    Science.gov (United States)

    Takahashi, Kazunori; Suzuki, Tatsuya; Ando, Akira

    2014-02-01

    Diameter of a permanent-magnets-expanded, radiofrequency (rf) plasma source is enlarged up to ∼13 cm for an application to a space propulsion device and tested with being attached to a diffusion chamber. The source is operated at 13.56 MHz 300 W rf power in low-pressure (40 mPa) argon. Measurement of ion energy distribution functions downstream of the source exit shows generation of a supersonic ion beam of about 20 eV. The detailed radial measurements demonstrate that the diameter and energy of the ion beam corresponds to the source tube diameter and the potential difference between the source and downstream plasmas, and that the radial profile of the beam flux is similar to the plasma density profile in the source cavity.

  17. On the phenomenon of the fast release of energy in irradiated solid methane: discussion of models considering the local space distribution of energy

    International Nuclear Information System (INIS)

    Shabalin, E.P.

    1995-01-01

    A general idea of the phenomenon, so-called 'a burp', is provided. It is concluded that no justified and consistent theory of the burp phenomenon is proposed. The paper expresses criticism on the application of the classic theory of homogeneous chemical reactions and of thermal explosion to analyze burps as it was in common usage up to now. Two hypotheses to explain features burps display are presented instead. Both of them have to do with mechanism of storing and releasing energy accounting for local non-uniformity of temperature end energy deposition. 11 refs., 4 figs

  18. Narrowband NIR-Induced In Situ Generation of the High-Energy Trans Conformer of Trichloroacetic Acid Isolated in Solid Nitrogen and its Spontaneous Decay by Tunneling to the Low-Energy Cis Conformer

    Directory of Open Access Journals (Sweden)

    R. F. G. Apóstolo

    2015-12-01

    Full Text Available The monomeric form of trichloroacetic acid (CCl3COOH; TCA was isolated in a cryogenic nitrogen matrix (15 K and the higher energy trans conformer (O=C–O–H dihedral: 180° was generated in situ by narrowband near-infrared selective excitation the 1st OH stretching overtone of the low-energy cis conformer (O=C–O–H dihedral: 0°. The spontaneous decay, by tunneling, of the generated high-energy conformer into the cis form was then evaluated and compared with those observed previously for the trans conformers of acetic and formic acids in identical experimental conditions. The much faster decay of the high-energy conformer of TCA compared to both formic and acetic acids (by ~35 and ca. 25 times, respectively was found to correlate well with the lower energy barrier for the trans→cis isomerization in the studied compound. The experimental studies received support from quantum chemistry calculations undertaken at the DFT(B3LYP/cc-pVDZ level of approximation, which allowed a detailed characterization of the potential energy surface of the molecule and the detailed assignment of the infrared spectra of the two conformers.

  19. Fission Fragment Mass Distributions and Total Kinetic Energy Release of 235-Uranium and 238-Uranium in Neutron-Induced Fission at Intermediate and Fast Neutron Energies

    Energy Technology Data Exchange (ETDEWEB)

    Duke, Dana Lynn [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-11-12

    This Ph.D. dissertation describes a measurement of the change in mass distributions and average total kinetic energy (TKE) release with increasing incident neutron energy for fission of 235U and 238U. Although fission was discovered over seventy-five years ago, open questions remain about the physics of the fission process. The energy of the incident neutron, En, changes the division of energy release in the resulting fission fragments, however, the details of energy partitioning remain ambiguous because the nucleus is a many-body quantum system. Creating a full theoretical model is difficult and experimental data to validate existing models are lacking. Additional fission measurements will lead to higher-quality models of the fission process, therefore improving applications such as the development of next-generation nuclear reactors and defense. This work also paves the way for precision experiments such as the Time Projection Chamber (TPC) for fission cross section measurements and the Spectrometer for Ion Determination in Fission (SPIDER) for precision mass yields.

  20. Understanding Drug Release Data through Thermodynamic Analysis

    Directory of Open Access Journals (Sweden)

    Marjorie Caroline Liberato Cavalcanti Freire

    2017-06-01

    Full Text Available Understanding the factors that can modify the drug release profile of a drug from a Drug-Delivery-System (DDS is a mandatory step to determine the effectiveness of new therapies. The aim of this study was to assess the Amphotericin-B (AmB kinetic release profiles from polymeric systems with different compositions and geometries and to correlate these profiles with the thermodynamic parameters through mathematical modeling. Film casting and electrospinning techniques were used to compare behavior of films and fibers, respectively. Release profiles from the DDSs were performed, and the mathematical modeling of the data was carried out. Activation energy, enthalpy, entropy and Gibbs free energy of the drug release process were determined. AmB release profiles showed that the relationship to overcome the enthalpic barrier was PVA-fiber > PVA-film > PLA-fiber > PLA-film. Drug release kinetics from the fibers and the films were better fitted on the Peppas–Sahlin and Higuchi models, respectively. The thermodynamic parameters corroborate these findings, revealing that the AmB release from the evaluated systems was an endothermic and non-spontaneous process. Thermodynamic parameters can be used to explain the drug kinetic release profiles. Such an approach is of utmost importance for DDS containing insoluble compounds, such as AmB, which is associated with an erratic bioavailability.

  1. Understanding Drug Release Data through Thermodynamic Analysis

    Science.gov (United States)

    Freire, Marjorie Caroline Liberato Cavalcanti; Alexandrino, Francisco; Marcelino, Henrique Rodrigues; Picciani, Paulo Henrique de Souza; Silva, Kattya Gyselle de Holanda e; Genre, Julieta; de Oliveira, Anselmo Gomes; do Egito, Eryvaldo Sócrates Tabosa

    2017-01-01

    Understanding the factors that can modify the drug release profile of a drug from a Drug-Delivery-System (DDS) is a mandatory step to determine the effectiveness of new therapies. The aim of this study was to assess the Amphotericin-B (AmB) kinetic release profiles from polymeric systems with different compositions and geometries and to correlate these profiles with the thermodynamic parameters through mathematical modeling. Film casting and electrospinning techniques were used to compare behavior of films and fibers, respectively. Release profiles from the DDSs were performed, and the mathematical modeling of the data was carried out. Activation energy, enthalpy, entropy and Gibbs free energy of the drug release process were determined. AmB release profiles showed that the relationship to overcome the enthalpic barrier was PVA-fiber > PVA-film > PLA-fiber > PLA-film. Drug release kinetics from the fibers and the films were better fitted on the Peppas–Sahlin and Higuchi models, respectively. The thermodynamic parameters corroborate these findings, revealing that the AmB release from the evaluated systems was an endothermic and non-spontaneous process. Thermodynamic parameters can be used to explain the drug kinetic release profiles. Such an approach is of utmost importance for DDS containing insoluble compounds, such as AmB, which is associated with an erratic bioavailability. PMID:28773009

  2. Observational study on the fine structure and dynamics of a solar jet. II. Energy release process revealed by spectral analysis

    Science.gov (United States)

    Sakaue, Takahito; Tei, Akiko; Asai, Ayumi; Ueno, Satoru; Ichimoto, Kiyoshi; Shibata, Kazunari

    2018-01-01

    We report on a solar jet phenomenon associated with the C5.4 class flare on 2014 November 11. The data of the jet was provided by the Solar Dynamics Observatory, the X-Ray Telescope (XRT) aboard Hinode, and the Interface Region Imaging Spectrograph and Domeless Solar Telescope (DST) at Hida Observatory, Kyoto University. These plentiful data enabled us to present this series of papers to discuss all the processes of the observed phenomena, including energy storage, event trigger, and energy release. In this paper, we focus on the energy release process of the observed jet, and mainly describe our spectral analysis on the Hα data of DST to investigate the internal structure of the Hα jet and its temporal evolution. This analysis reveals that in the physical quantity distributions of the Hα jet, such as line-of-sight velocity and optical thickness, there is a significant gradient in the direction crossing the jet. We interpret this internal structure as the consequence of the migration of the energy release site, based on the idea of ubiquitous reconnection. Moreover, by measuring the horizontal flow of the fine structures in the jet, we succeeded in deriving the three-dimensional velocity field and the line-of-sight acceleration field of the Hα jet. The analysis result indicates that part of the ejecta in the Hα jet experienced additional acceleration after it had been ejected from the lower atmosphere. This secondary acceleration was found to occur in the vicinity of the intersection between the trajectories of the Hα jet and the X-ray jet observed by Hinode/XRT. We propose that a fundamental cause of this phenomenon is magnetic reconnection involving the plasmoid in the observed jet.

  3. The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity: human and rodent perspectives.

    Science.gov (United States)

    Garland, Theodore; Schutz, Heidi; Chappell, Mark A; Keeney, Brooke K; Meek, Thomas H; Copes, Lynn E; Acosta, Wendy; Drenowatz, Clemens; Maciel, Robert C; van Dijk, Gertjan; Kotz, Catherine M; Eisenmann, Joey C

    2011-01-15

    Mammals expend energy in many ways, including basic cellular maintenance and repair, digestion, thermoregulation, locomotion, growth and reproduction. These processes can vary tremendously among species and individuals, potentially leading to large variation in daily energy expenditure (DEE). Locomotor energy costs can be substantial for large-bodied species and those with high-activity lifestyles. For humans in industrialized societies, locomotion necessary for daily activities is often relatively low, so it has been presumed that activity energy expenditure and DEE are lower than in our ancestors. Whether this is true and has contributed to a rise in obesity is controversial. In humans, much attention has centered on spontaneous physical activity (SPA) or non-exercise activity thermogenesis (NEAT), the latter sometimes defined so broadly as to include all energy expended due to activity, exclusive of volitional exercise. Given that most people in Western societies engage in little voluntary exercise, increasing NEAT may be an effective way to maintain DEE and combat overweight and obesity. One way to promote NEAT is to decrease the amount of time spent on sedentary behaviours (e.g. watching television). The effects of voluntary exercise on other components of physical activity are highly variable in humans, partly as a function of age, and have rarely been studied in rodents. However, most rodent studies indicate that food consumption increases in the presence of wheels; therefore, other aspects of physical activity are not reduced enough to compensate for the energetic cost of wheel running. Most rodent studies also show negative effects of wheel access on body fat, especially in males. Sedentary behaviours per se have not been studied in rodents in relation to obesity. Several lines of evidence demonstrate the important role of dopamine, in addition to other neural signaling networks (e.g. the endocannabinoid system), in the control of voluntary exercise. A

  4. Magnetohydrodynamic and thermal processes in solar flare energy build-up and release

    International Nuclear Information System (INIS)

    Tend, W. van.

    1979-01-01

    A solar flare can be described as an instability in the upper solar atmosphere that converts 10 28 ergs to 10 32 ergs of magnetic energy into other forms of energy, mainly kinetic energy. The solar flare gives rise to a wealth of observable phenomena. The author develops a fairly simple model to explain many of these apparently very diverse features of solar flares. (Auth.)

  5. An efficient and accurate method for computation of energy release rates in beam structures with longitudinal cracks

    DEFF Research Database (Denmark)

    Blasques, José Pedro Albergaria Amaral; Bitsche, Robert

    2015-01-01

    This paper proposes a novel, efficient, and accurate framework for fracture analysis of beam structures with longitudinal cracks. The three-dimensional local stress field is determined using a high-fidelity beam model incorporating a finite element based cross section analysis tool. The Virtual...... Crack Closure Technique is used for computation of strain energy release rates. The devised framework was employed for analysis of cracks in beams with different cross section geometries. The results show that the accuracy of the proposed method is comparable to that of conventional three...

  6. Analysis and prospectives of the mechanism of release of energy efficiency titles

    International Nuclear Information System (INIS)

    Pastore, P.

    2009-01-01

    Starting from the Third annual report on the mechanism of release of energetic efficiency titles and considering the Decree Ministerial 21/12/2007, there is an analysis of the better aspects of the mechanism of release of energetic efficiency titles introduced from the norms regarding the previous annual relations. Particularly important is the role carried out from the Authority of the Electric Power and the Gas in the action of control and monitoring of the market. In this direction they have been formulated various deliberations. Analyzing the results obtained from the market of energetic efficiency titles in the course of 2007, it has been caught up 98% of the established objectives. In the course of the same year they have been cancelled many titles, as a result of verification activity. The obtained results refer to the geographic distribution, to the exchanged volumes and to the costs of the titles. At last some criticalities are placed in evidence that remain in the mechanism and that they can be resolved in order to improve the market. [it

  7. Energy dispersive X-ray microanalysis, fluoride release, and antimicrobial properties of glass ionomer cements indicated for atraumatic restorative treatment.

    Science.gov (United States)

    Saxena, Sudhanshu; Tiwari, Sonia

    2016-01-01

    The aim of this study was to compare constituents of glass powder, fluoride release, and antimicrobial properties of new atraumatic restorative treatment material with zirconia fillers and conventional glass ionomer cement (GIC) type IX. Thisin vitro study comparing Zirconomer and Fuji IX was executed in three parts: (1) energy dispersive X-ray microanalysis of glass powders (2) analysis of fluoride release at 1(st), 3(rd), 7(th), 15(th), and 30(th) day, and (3) antimicrobial activity against Streptococcus mutans, Lactobacillus casei, and Candida albicans at 48 hours. Data was analyzed using unpaired t-test and two way analysis of variance followed by least significant difference post hoc test. A P value of glass powders, mean atomic percentage of oxygen was more than 50%. According to the weight percentage, zirconium in Zirconomer and silica in Fuji IX were the second main elements. Calcium, zinc, and zirconium were observed only in Zirconomer. At all the time intervals, statistically significant higher amount of fluoride release was observed with Zirconomer than Fuji IX. At 48 hours, mean ± standard deviation (SD) of zone of inhibition against Streptococcus mutans was 11.14 ± 0.77 mm and 8.51 ± 0.43 mm for Zirconomer and Fuji IX, respectively. Against Lactobacillus casei, it was 14.06 ± 0.71 mm for Zirconomer and 11.70 ± 0.39 mm for Fuji IX. No antifungal activity was observed against Candida albicans by Zirconomer and Fuji IX. Zirconomer had higher antibacterial activity against Streptococcus mutans and Lactobacillus casei, which may be attributed to its composition and higher fluoride release. However, it failed to show antifungal effect againstCandida albicans.

  8. Lack of stimulation of 24-hour growth hormone release by hypocaloric diet in obesity

    DEFF Research Database (Denmark)

    Rasmussen, M H; Juul, A; Kjems, L L

    1995-01-01

    Obesity is associated with a marked reduction in the spontaneous secretion of GH. To investigate the effect of acute alterations in calorie intake on GH release, 24-hr spontaneous GH release was measured during habitual calorie intake as well as during a short term, very low calorie diet (VLCD......-I (IGF-I), IGF-binding protein-1 (IGFBP-1), IGF-binding protein-3 (IGFBP-3), insulin, pro-insulin, and blood glucose were measured during habitual energy intake as well as during the hypocaloric diet. Twenty-four-hour GH release profiles and IGFBP-1 were decreased, and insulin as well as proinsulin....... This suggests a reversible defect in GH release, rather than a persistent preexisting disorder. It is hypothesized that enhanced bioavailability of IGF-I, acting in concert with elevated proinsulin and insulin levels, may account for the lack of stimulation of 24-hr GH release by the hypocaloric diet in obese...

  9. EIA new releases

    International Nuclear Information System (INIS)

    1994-09-01

    This report is a compliation of news releases from the Energy Information Administration. The september-october report includes articles on energy conservation, energy consumption in commercial buildings, and a short term energy model for a personal computer

  10. Surface Meteorology and Solar Energy (SSE) Data Release 5.1

    Science.gov (United States)

    Stackhouse, Paul W. (Principal Investigator)

    The Surface meteorology and Solar Energy (SSE) data set contains over 200 parameters formulated for assessing and designing renewable energy systems.The SSE data set is formulated from NASA satellite- and reanalysis-derived insolation and meteorological data for the 10-year period July 1983 through June 1993. Results are provided for 1 degree latitude by 1 degree longitude grid cells over the globe. Average daily and monthly measurements for 1195 World Radiation Data Centre ground sites are also available. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1983-07-01; Stop_Date=1993-06-30] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Latitude_Resolution=1 degree; Longitude_Resolution=1 degree].

  11. Multifunctional glass fiber/polyamide composites with thermal energy storage/release capability

    OpenAIRE

    G. Fredi; A. Dorigato; A. Pegoretti

    2018-01-01

    Thermoplastic composite laminates with thermal energy storage (TES) capability were prepared by combining a glass fabric, a polyamide 12 (PA12) matrix and two different phase change materials (PCMs), i.e. a paraffinic wax microencapsulated in melamine-formaldehyde shells and a paraffin shape stabilized with carbon nanotubes. The melt flow index of the PA12/PCM blends decreased with the PCM concentration, especially in the systems with shape stabilized wax. Differential scanning calorimetry sh...

  12. Energy transport by energetic electrons released during solar flares. I - Thermal versus nonthermal processes

    Science.gov (United States)

    Winglee, R. M.; Dulk, G. A.; Pritchett, P. L.

    1988-01-01

    The propagation of energetic electrons through a flaring flux tube is studied in an attempt to determine how the energy of the electrons is deposited in the flux tube. One-dimensional electrostatic particle simulations are used in the present investigation. As the energetic electrons propagate into the system, a return current of ambient plasma electrons and some of the energetic electrons is drawn into the energetic electron source. It is found that, as the ambient temperature relative to the ion temperature increases above about 3, the heated return-current electrons can excite ion-sound waves.

  13. Multifunctional glass fiber/polyamide composites with thermal energy storage/release capability

    Directory of Open Access Journals (Sweden)

    G. Fredi

    2018-04-01

    Full Text Available Thermoplastic composite laminates with thermal energy storage (TES capability were prepared by combining a glass fabric, a polyamide 12 (PA12 matrix and two different phase change materials (PCMs, i.e. a paraffinic wax microencapsulated in melamine-formaldehyde shells and a paraffin shape stabilized with carbon nanotubes. The melt flow index of the PA12/PCM blends decreased with the PCM concentration, especially in the systems with shape stabilized wax. Differential scanning calorimetry showed that, for the matrices with microcapsules, the values of enthalpy were approximately the 70% of the theoretical values, which was attributed to the fracture of some microcapsules. Nevertheless, most of the energy storage capability was preserved. On the other hand, much lower relative enthalpy values were measured on the composites with shape stabilized wax, due to a considerable paraffin leakage or degradation. The subsequent characterization of the glass fabric laminates highlighted that the fiber and void volume fractions were comparable for all the laminates except for that with the higher amount of shape stabilized wax, where the high viscosity of the matrix led to a low fiber volume fraction and higher void content. The mechanical properties of the laminates were only slightly impaired by PCM addition, while a more sensible drop of the elastic modulus, of the stress at break and of the interlaminar shear strength could be observed in the shape stabilized wax systems.

  14. Idaho National Engineering Laboratory response to the December 13, 1991, Congressional inquiry on offsite release of hazardous and solid waste containing radioactive materials from Department of Energy facilities

    International Nuclear Information System (INIS)

    Shapiro, C.; Garcia, K.M.; McMurtrey, C.D.; Williams, K.L.; Jordan, P.J.

    1992-05-01

    This report is a response to the December 13, 1991, Congressional inquiry that requested information on all hazardous and solid waste containing radioactive materials sent from Department of Energy facilities to offsite facilities for treatment or disposal since January 1, 1981. This response is for the Idaho National Engineering Laboratory. Other Department of Energy laboratories are preparing responses for their respective operations. The request includes ten questions, which the report divides into three parts, each responding to a related group of questions. Part 1 answers Questions 5, 6, and 7, which call for a description of Department of Energy and contractor documentation governing the release of waste containing radioactive materials to offsite facilities. ''Offsite'' is defined as non-Department of Energy and non-Department of Defense facilities, such as commercial facilities. Also requested is a description of the review process for relevant release criteria and a list of afl Department of Energy and contractor documents concerning release criteria as of January 1, 1981. Part 2 answers Questions 4, 8, and 9, which call for information about actual releases of waste containing radioactive materials to offsite facilities from 1981 to the present, including radiation levels and pertinent documentation. Part 3 answers Question 10, which requests a description of the process for selecting offsite facilities for treatment or disposal of waste from Department of Energy facilities. In accordance with instructions from the Department of Energy, the report does not address Questions 1, 2, and 3

  15. Spontaneous pneumothorax in weightlifters.

    Science.gov (United States)

    Marnejon, T; Sarac, S; Cropp, A J

    1995-06-01

    Spontaneous pneumothorax is infrequently caused by strenuous exertion. To our knowledge there has only been one case of spontaneous pneumothorax associated with weightlifting reported in the medical literature. We describe three consecutive cases of spontaneous pneumothorax associated with weightlifting. We postulate that spontaneous pneumothorax in these patients may be secondary to improper breathing techniques. It is important that physicians and weight trainers be aware of the association between weight lifting and spontaneous pneumothorax and assure that proper instruction is given to athletes who work with weights.

  16. Effect of synchronizing the rate of degradation of dietary energy and nitrogen release on growth performance in Brahman cattle

    Directory of Open Access Journals (Sweden)

    Virote Pattarajinda

    2006-01-01

    Full Text Available The objective of this research was to determine the effect of synchronizing the rate of degradation of dietary energy and nitrogen release on growth performance in Brahman beef cattle. Fifteen Brahman cattle, 1.5 years old, with an average initial body weight of 184.8±11.1 kg were assigned to one of three treatments according to a randomized complete block design. Dietary treatments contained 3 levels of synchrony index (0.39, 0.56 and 0.74 that were derived from laboratory chemical composition analysis and degradation kinetics using nylon bag technique. Diets were fed at the rate of 2.5% BW by separate concentrate and roughage. Average daily gain increased linearly (P<0.05 with increase levels of synchrony index in the diets. The digestibility of dry matter, organic matter and neutral detergent fiber increased linearly (P<0.01. The digestibility of acid detergent fiber increased linearly (P<0.05. Ruminal total volatile fatty acids concentration increased linearly (P<0.05 at 6 h post feeding. Higher concentration and fluctuation of ruminal ammonia nitrogen and blood urea nitrogen were observed in animals that received lower synchrony index in their diets. Rumen microbial population tended to increase with diets having higher levels of synchrony index. The results indicated that synchronized rate of dietary energy and nitrogen degradation improved ruminal fermentation and digestibility, thus this increased the growth rate in Brahman cattle fed with ricestraw- based diets.

  17. Theoretical prediction of energy release rate for interface crack initiation by thermal stress in environmental barrier coatings for ceramics

    Science.gov (United States)

    Kawai, E.; Umeno, Y.

    2017-05-01

    As weight reduction of turbines for aircraft engines is demanded to improve fuel consumption and curb emission of carbon dioxide, silicon carbide (SiC) fiber reinforced SiC matrix composites (SiC/SiC) are drawing enormous attention as high-pressure turbine materials. For preventing degradation of SiC/SiC, environmental barrier coatings (EBC) for ceramics are deposited on the composites. The purpose of this study is to establish theoretical guidelines for structural design which ensures the mechanical reliability of EBC. We conducted finite element method (FEM) analysis to calculate energy release rates (ERRs) for interface crack initiation due to thermal stress in EBC consisting of Si-based bond coat, Mullite and Ytterbium (Yb)-silicate layers on a SiC/SiC substrate. In the FEM analysis, the thickness of one EBC layer was changed from 25 μm to 200 μm while the thicknesses of the other layers were fixed at 25 μm, 50 μm and 100 μm. We compared ERRs obtained by the FEM analysis and a simple theory for interface crack in a single-layered structure where ERR is estimated as nominal strain energy in the coating layers multiplied by a constant factor (independent of layer thicknesses). We found that, unlike the case of single-layered structures, the multiplication factor is no longer a constant but is determined by the combination of consisting coating layer thicknesses.

  18. Fission-product energy release for times following thermal-neutron fission of 235U between 2 and 14000 seconds

    International Nuclear Information System (INIS)

    Dickens, J.K.; Emery, J.F.; Love, T.A.; McConnell, J.W.; Northcutt, K.J.; Peelle, R.W.; Weaver, H.

    1977-10-01

    Fission-product decay energy-releases rates were measured for thermal-neutron fission of 235 U. Samples of mass 1 to 10 μg were irradiated for 1 to 100 sec by use of the fast pneumatic-tube facility at the Oak Ridge Research Reactor. The resulting beta- and gamma-ray emissions were counted for times-after-fission between 2 and 14,000 seconds. The data were obtained for beta and gamma rays separately as spectral distributions, N(E/sub γ/) vs E/sub γ/ and N(E/sub beta/) vs E/sub β/. For the gamma-ray data the spectra were obtained by using a NaI detector, while for the beta-ray data the spectra were obtained by using an NE-110 detector with an anticoincidence mantle. The raw data were unfolded to provide spectral distributions of modest resolution. These were integrated over E/sub γ/ and E/sub β/ to provide total yield and energy integrals as a function of time after fission. Results are low compared to the present 1973 ANS Decay-heat standard. A complete description of the experimental apparatus and data-reduction techniques is presented. The final integral data are given in tabular and graphical form and are compared with published data. 41 figures, 13 tables

  19. Dispersions and correlations of the distributions of products of 252Cf spontaneous fission

    International Nuclear Information System (INIS)

    Vidyakin, G.S.; Vyrodov, V.N.; Gurevich, I.I.; Kirillov, B.F.; Kozlov, Y.V.; Martem'yanov, V.P.; Sukhotin, S.V.; Tarasenkov, V.G.; Khakimov, S.K.

    1982-01-01

    We report the results of two experiments on study of the dispersions and correlations of the distributions of products of the spontaneous fission of 252 Cf. In each experiment about 10 8 fissions were recorded with simultaneous measurement of the number of neutrons produced and in one case the fragment kinetic energy and in the other case the energy of the prompt #betta# rays. The quantities obtained were the probabilities of production of a given number of neutrons per fission, the dispersions of the distributions of the number of neutrons produced and of the fragment kinetic energy, and the dependence of the average #betta#-ray energy and the average fragment kinetic energy on the number of neutrons produced. A calculation is made of the spectrum of the total energy carried away by fragments and neutrons, and its dispersion is determined. An estimate of the total energy release in the 252 Cf fission process is made

  20. Use of leaching tests to quantify trace element release from waste to energy bottom ash amended pavements.

    Science.gov (United States)

    Roessler, Justin G; Townsend, Timothy G; Ferraro, Christopher C

    2015-12-30

    A series of roadway tests strips were paved on-site at a landfill in Florida, U.S. Waste to energy (WTE) bottom ash was used as a partial course aggregate replacement in a hot mix asphalt (HMA) and a Portland cement concrete (PCC) pavement, along with control HMA and PCC sections. This allowed for a comparison of the relative degree of leaching between both materials (HMA and PCC) as well as between the ash-amended and control pavements. Batch and monolithic tank leaching tests were conducted on the pavements. Testing of the PCC samples demonstrated that Mo and Al were elevated above regulatory thresholds for both the control and ash amended samples. Further leach testing demonstrated that the release of Mo was likely from the PCC and not a result of the inclusion of the BA into pavement. Batch leach testing of ash-amended HMA samples revealed Sb as a constituent of potential concern. The results of the monolith leaching test displayed leaching of Sb within the same order of magnitude as the regulatory threshold. Calculation of the leachability index (LI) for Sb found that it would have limited mobility when incorporated in the HMA matrix. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Load-Unload Response Ratio and Accelerating Moment/Energy Release Critical Region Scaling and Earthquake Prediction

    Science.gov (United States)

    Yin, X. C.; Mora, P.; Peng, K.; Wang, Y. C.; Weatherley, D.

    The main idea of the Load-Unload Response Ratio (LURR) is that when a system is stable, its response to loading corresponds to its response to unloading, whereas when the system is approaching an unstable state, the response to loading and unloading becomes quite different. High LURR values and observations of Accelerating Moment/Energy Release (AMR/AER) prior to large earthquakes have led different research groups to suggest intermediate-term earthquake prediction is possible and imply that the LURR and AMR/AER observations may have a similar physical origin. To study this possibility, we conducted a retrospective examination of several Australian and Chinese earthquakes with magnitudes ranging from 5.0 to 7.9, including Australia's deadly Newcastle earthquake and the devastating Tangshan earthquake. Both LURR values and best-fit power-law time-to-failure functions were computed using data within a range of distances from the epicenter. Like the best-fit power-law fits in AMR/AER, the LURR value was optimal using data within a certain epicentral distance implying a critical region for LURR. Furthermore, LURR critical region size scales with mainshock magnitude and is similar to the AMR/AER critical region size. These results suggest a common physical origin for both the AMR/AER and LURR observations. Further research may provide clues that yield an understanding of this mechanism and help lead to a solid foundation for intermediate-term earthquake prediction.

  2. Methodology report on the calculation of emissions to air from the sectors Energy, Industry and Waste (Update 2016), as used by the Dutch Pollutant Release and Transfer Register

    NARCIS (Netherlands)

    Peek CJ; Montfoort JA; Droge R; Guis B; Baas C; van Huet B; van Hunnik OR; van den Berghe ACWM; DMO; MIL

    2017-01-01

    In this technical report RIVM describes the updated methods that The Netherlands Pollutant Release and Transfer Register uses to calculate the emissions of contaminated substances into the air from the Industry, Energy Generating and Waste Processing sectors. Due to international treaties, such

  3. Spontaneous uterine rupture

    African Journals Online (AJOL)

    ABSTRACT. Rupture of a gravid uterus is a surgical emergency. Predisposing factors include a scarred uterus. Spontaneous rupture of an unscarred uterus during pregnancy is a rare occurrence. We hereby present the case of a spontaneous complete uterine rupture at a gestational age of 34 weeks in a 35 year old patient ...

  4. Spontaneous intracranial hypotension.

    LENUS (Irish Health Repository)

    Fullam, L

    2012-01-31

    INTRODUCTION: Spontaneous\\/primary intracranial hypotension is characterised by orthostatic headache and is associated with characteristic magnetic resonance imaging findings. CASE REPORT: We present a case report of a patient with typical symptoms and classical radiological images. DISCUSSION: Spontaneous intracranial hypotension is an under-recognised cause of headache and can be diagnosed by history of typical orthostatic headache and findings on MRI brain.

  5. OzDES multifibre spectroscopy for the Dark Energy Survey: 3-yr results and first data release

    Science.gov (United States)

    Childress, M. J.; Lidman, C.; Davis, T. M.; Tucker, B. E.; Asorey, J.; Yuan, F.; Abbott, T. M. C.; Abdalla, F. B.; Allam, S.; Annis, J.; Banerji, M.; Benoit-Lévy, A.; Bernard, S. R.; Bertin, E.; Brooks, D.; Buckley-Geer, E.; Burke, D. L.; Carnero Rosell, A.; Carollo, D.; Carrasco Kind, M.; Carretero, J.; Castander, F. J.; Cunha, C. E.; da Costa, L. N.; D'Andrea, C. B.; Doel, P.; Eifler, T. F.; Evrard, A. E.; Flaugher, B.; Foley, R. J.; Fosalba, P.; Frieman, J.; García-Bellido, J.; Glazebrook, K.; Goldstein, D. A.; Gruen, D.; Gruendl, R. A.; Gschwend, J.; Gupta, R. R.; Gutierrez, G.; Hinton, S. R.; Hoormann, J. K.; James, D. J.; Kessler, R.; Kim, A. G.; King, A. L.; Kovacs, E.; Kuehn, K.; Kuhlmann, S.; Kuropatkin, N.; Lagattuta, D. J.; Lewis, G. F.; Li, T. S.; Lima, M.; Lin, H.; Macaulay, E.; Maia, M. A. G.; Marriner, J.; March, M.; Marshall, J. L.; Martini, P.; McMahon, R. G.; Menanteau, F.; Miquel, R.; Moller, A.; Morganson, E.; Mould, J.; Mudd, D.; Muthukrishna, D.; Nichol, R. C.; Nord, B.; Ogando, R. L. C.; Ostrovski, F.; Parkinson, D.; Plazas, A. A.; Reed, S. L.; Reil, K.; Romer, A. K.; Rykoff, E. S.; Sako, M.; Sanchez, E.; Scarpine, V.; Schindler, R.; Schubnell, M.; Scolnic, D.; Sevilla-Noarbe, I.; Seymour, N.; Sharp, R.; Smith, M.; Soares-Santos, M.; Sobreira, F.; Sommer, N. E.; Spinka, H.; Suchyta, E.; Sullivan, M.; Swanson, M. E. C.; Tarle, G.; Uddin, S. A.; Walker, A. R.; Wester, W.; Zhang, B. R.

    2017-11-01

    We present results for the first three years of OzDES, a six year programme to obtain redshifts for objects in the Dark Energy Survey (DES) supernova fields using the 2dF fibre positioner and AAOmega spectrograph on the Anglo-Australian Telescope. OzDES is a multi-object spectroscopic survey targeting multiple types of targets at multiple epochs over a multiyear baseline and is one of the first multi-object spectroscopic surveys to dynamically include transients into the target list soon after their discovery. At the end of three years, OzDES has spectroscopically confirmed almost 100 supernovae, and has measured redshifts for 17 000 objects, including the redshifts of 2566 supernova hosts. We examine how our ability to measure redshifts for targets of various types depends on signal-to-noise ratio (S/N), magnitude and exposure time, finding that our redshift success rate increases significantly at a S/N of 2-3 per 1-Å bin. We also find that the change in S/N with exposure time closely matches the Poisson limit for stacked exposures as long as 10 h. We use these results to predict the redshift yield of the full OzDES survey, as well as the potential yields of future surveys on other facilities such as (i.e. the 4-m Multi-Object Spectroscopic Telescope, the Subaru Prime Focus Spectrograph and the Maunakea Spectroscopic Explorer). This work marks the first OzDES data release, comprising 14 693 redshifts. OzDES is on target to obtain over 30 000 redshifts over the 6-yr duration of the survey, including a yield of approximately 5700 supernova host-galaxy redshifts.

  6. GdNCT of spontaneous canine melanoma

    International Nuclear Information System (INIS)

    Mitin, V.N.; Kulakov, V.N.; Khokhlov, V.F.

    2006-01-01

    The effectiveness of GdNCT has been studied in dogs with spontaneous melanoma of the mucousmembrane of the oral cavity patients on the NCT base at the IRT MEPhI reactor. The control group with melanomas was treated with neutrons. Fourteen canine patients were selected in the Clinic of Experimental Therapy affiliated with the RCRC RAMS. The calculation of doses has shown that the total dose of energy release depending on Gd concentration in the target can be several times higher than the dose produced by the reactor neutron beam. The calculations were carried out using the diffusion pharmacokinetic model. The gadolinium drug dipentast was administered intratumorally immediately prior to irradiation. The tumor size was estimated by measuring it in three projections. The tumor was irradiated for 60-90 minutes with a thermal neutron flux of 0.7x10 9 n/cm 2 s. The dose on tumor was 80-120 Gy, on surrounding tissues - 12-15 Gy. The treatment plan included immunotherapy with Roncoleikin in a dose of (15-10)x10 3 IE/kg. The results of GdNCT are still under observation. The results conform to those obtained by us earlier in cell cultures and inoculated experimental tumors. GdNCT is also effective in combination with immunotherapy. (author)

  7. The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity : human and rodent perspectives

    NARCIS (Netherlands)

    Garland, Theodore; Schutz, Heidi; Chappell, Mark A.; Keeney, Brooke K.; Meek, Thomas H.; Copes, Lynn E.; Acosta, Wendy; Drenowatz, Clemens; Maciel, Robert C.; van Dijk, Gertjan; Kotz, Catherine M.; Eisenmann, Joey C.; Garland, Jr.

    Mammals expend energy in many ways, including basic cellular maintenance and repair, digestion, thermoregulation, locomotion, growth and reproduction. These processes can vary tremendously among species and individuals, potentially leading to large variation in daily energy expenditure (DEE).

  8. Rapid fabrication of superhydrophobic Al/Fe{sub 2}O{sub 3} nanothermite film with excellent energy-release characteristics and long-term storage stability

    Energy Technology Data Exchange (ETDEWEB)

    Ke, Xiang; Zhou, Xiang, E-mail: zhouxiang@njust.edu.cn; Hao, Gaozi; Xiao, Lei; Liu, Jie; Jiang, Wei, E-mail: superfine_jw@126.com

    2017-06-15

    Highlights: • Superhydrophobic Al/Fe{sub 2}O{sub 3} nanothermite film is prepared by combining electrophoretic deposition and surface modification technologies. • The deposition system and kinetics of electrophoretic deposition process are investigated to optimize parameters to obtain smooth films. • Energy-release characteristics of superhydrophobic films are significantly improved for both fresh and aged samples. • Superhydrophobic films exhibit excellent long-time storage stability both in natural and accelerated aging test. • A preignition reaction is found to enhance the energy-release characteristics of superhydrophobic nanothermite film. - Abstract: One of the challenges for the application of energetic materials is their energy-retaining capabilities after long-term storage. In this study, we report a facile method to fabricate superhydrophobic Al/Fe{sub 2}O{sub 3} nanothermite film by combining electrophoretic deposition and surface modification technologies. Different concentrations of dispersion solvents and additives are investigated to optimize the deposition parameters. Meanwhile, the dependence of deposition rates on nanoparticle concentrations is also studied. The surface morphology and chemical composition are characterized by field-emission scanning electron microscopy, X-ray diffraction, X-ray energy-dispersive spectroscopy, and X-ray photoelectron spectroscopy. A static contact angles as high as 156° shows the superhydrophobicity of the nanothermite film. Natural and accelerated aging tests are performed and the thermal behavior is analyzed. Thermal analysis shows that the surface modification contributes to significantly improved energy-release characteristics for both fresh and aged samples, which is supposed to be attributed to the preignition reaction between Al{sub 2}O{sub 3} shell and FAS-17. Superhydrophobic Al/Fe{sub 2}O{sub 3} nanothermite film exhibits excellent long-time storage stability with 83.4% of energy left in

  9. Fission fragment yields and total kinetic energy release in neutron-induced fission of235,238U,and239Pu

    Science.gov (United States)

    Tovesson, F.; Duke, D.; Geppert-Kleinrath, V.; Manning, B.; Mayorov, D.; Mosby, S.; Schmitt, K.

    2018-03-01

    Different aspects of the nuclear fission process have been studied at Los Alamos Neutron Science Center (LANSCE) using various instruments and experimental techniques. Properties of the fragments emitted in fission have been investigated using Frisch-grid ionization chambers, a Time Projection Chamber (TPC), and the SPIDER instrument which employs the 2v-2E method. These instruments and experimental techniques have been used to determine fission product mass yields, the energy dependent total kinetic energy (TKE) release, and anisotropy in neutron-induced fission of U-235, U-238 and Pu-239.

  10. Renal epithelial cells can release ATP by vesicular fusion

    Directory of Open Access Journals (Sweden)

    Randi G Bjaelde

    2013-09-01

    Full Text Available Renal epithelial cells have the ability to release nucleotides as paracrine factors. In the intercalated cells of the collecting duct, ATP is released by connexin30 (cx30, which is selectively expressed in this cell type. However, ATP is released by virtually all renal epithelia and the aim of the present study was to identify possible alternative nucleotide release pathways in a renal epithelial cell model. We used MDCK (type1 cells to screen for various potential ATP release pathways. In these cells, inhibition of the vesicular H+-ATPases (bafilomycin reduced both the spontaneous and hypotonically (80%-induced nucleotide release. Interference with vesicular fusion using N-ethylamide markedly reduced the spontaneous nucleotide release, as did interference with trafficking from the endoplasmic reticulum to the Golgi apparatus (brefeldin A1 and vesicular transport (nocodazole. These findings were substantiated using a siRNA directed against SNAP-23, which significantly reduced spontaneous ATP release. Inhibition of pannexin and connexins did not affect the spontaneous ATP release in this cell type, which consists of ∼90% principal cells. TIRF-microscopy of either fluorescently-labeled ATP (MANT-ATP or quinacrine-loaded vesicles, revealed that spontaneous release of single vesicles could be promoted by either hypoosmolality (50% or ionomycin. This vesicular release decreased the overall cellular fluorescence by 5.8% and 7.6% respectively. In summary, this study supports the notion that spontaneous and induced ATP release can occur via exocytosis in renal epithelial cells.

  11. Energy efficient bead milling of microalgae: Effect of bead size on disintegration and release of proteins and carbohydrates

    NARCIS (Netherlands)

    Postma, P.R.; Suarez Garcia, E.; Safi, Carl; Yonathan, K.; Olivieri, G.; Barbosa, M.J.; Wijffels, R.H.; Eppink, M.H.M.

    2017-01-01

    The disintegration of three industry relevant algae (Chlorella vulgaris, Neochloris oleoabundans and Tetraselmis suecica) was studied in a lab scale bead mill at different bead sizes (0.3–1 mm). Cell disintegration, proteins and carbohydrates released into the water phase followed a first order

  12. PERIODIC-SOLUTIONS IN SPONTANEOUSLY BROKEN THEORIES

    NARCIS (Netherlands)

    BRIHAYE, Y; KUNZ, J

    A class of spontaneously broken field theories is proposed, and the occurrence of their periodic, classical solutions is investigated in detail. The emergence of multiple solutions is observed, their normal modes of oscillation are studied, and the bifurcations of the classical energy functional are

  13. Spontaneous Atraumatic Mediastinal Hemorrhage

    Directory of Open Access Journals (Sweden)

    Morkos Iskander BSc, BMBS, MRCS, PGCertMedEd

    2013-04-01

    Full Text Available Spontaneous atraumatic mediastinal hematomas are rare. We present a case of a previously fit and well middle-aged lady who presented with acute breathlessness and an increasing neck swelling and spontaneous neck bruising. On plain chest radiograph, widening of the mediastinum was noted. The bruising was later confirmed to be secondary to mediastinal hematoma. This life-threatening diagnostic conundrum was managed conservatively with a multidisciplinary team approach involving upper gastrointestinal and thoracic surgeons, gastroenterologists, radiologists, intensivists, and hematologists along with a variety of diagnostic modalities. A review of literature is also presented to help surgeons manage such challenging and complicated cases.

  14. Total kinetic energy release in 239Pu(n ,f ) post-neutron emission from 0.5 to 50 MeV incident neutron energy

    Science.gov (United States)

    Meierbachtol, K.; Tovesson, F.; Duke, D. L.; Geppert-Kleinrath, V.; Manning, B.; Meharchand, R.; Mosby, S.; Shields, D.

    2016-09-01

    The average total kinetic energy (T K E ¯) in 239Pu(n ,f ) has been measured for incident neutron energies between 0.5 and 50 MeV. The experiment was performed at the Los Alamos Neutron Science Center (LANSCE) using the neutron time-of-flight technique, and the kinetic energy of fission fragments post-neutron emission was measured in a double Frisch-gridded ionization chamber. This represents the first experimental study of the energy dependence of T K E ¯ in 239Pu above neutron energies of 6 MeV.

  15. Spontaneous Appendicocutaneous Fistula I

    African Journals Online (AJOL)

    M T0k0de* MB, BS and. Dr 0. A. AWOj0bi+ FMCS (Nig). ABSTRACT. Ruptured appendicitis is not a common cause of spontaneous enterocutaneous fistula. A case of ruptured retrocaecal appendicitis presenting as an enterocutaneous fistula in a Nigerian woman is presented. The literature on this disorder is also reviewed.

  16. [Spontaneous bacterial peritonitis].

    Science.gov (United States)

    Strauss, Edna; Caly, Wanda Regina

    2003-01-01

    Spontaneous bacterial peritonitis occurs in 30% of patients with ascites due to cirrhosis leading to high morbidity and mortality rates. The pathogenesis of spontaneous bacterial peritonitis is related to altered host defenses observed in end-stage liver disease, overgrowth of microorganisms, and bacterial translocation from the intestinal lumen to mesenteric lymph nodes. Clinical manifestations vary from severe to slight or absent, demanding analysis of the ascitic fluid. The diagnosis is confirmed by a number of neutrophils over 250/mm3 associated or not to bacterial growth in culture of an ascites sample. Enterobacteriae prevail and Escherichia coli has been the most frequent bacterium reported. Mortality rates decreased markedly in the last two decades due to early diagnosis and prompt antibiotic treatment. Third generation intravenous cephalosporins are effective in 70% to 95% of the cases. Recurrence of spontaneous bacterial peritonitis is common and can be prevented by the continuous use of oral norfloxacin. The development of bacterial resistance demands the search for new options in the prophylaxis of spontaneous bacterial peritonitis; probiotics are a promising new approach, but deserve further evaluation. Short-term antibiotic prophylaxis is recommended for patients with cirrhosis and ascites shortly after an acute episode of gastrointestinal bleeding.

  17. Spontaneous Grammar Explanations.

    Science.gov (United States)

    Tjoo, Hong Sing; Lewis, Marilyn

    1998-01-01

    Describes one New Zealand university language teacher's reflection on her own grammar explanations to university-level students of Bahasa Indonesian. Examines form-focused instruction through the teacher's spontaneous answers to students' questions about the form of the language they are studying. The teacher's experiences show that it takes time…

  18. EDITORIAL SPONTANEOUS BACTERIAL PERITONITIS ...

    African Journals Online (AJOL)

    hi-tech

    Spontaneous bacterial peritonitis (SBP) frequent]y occurs in patients with liver cirrhosis and ascites. It is defined as an infection of previously sterile ascitic fluid without any demonstrable intrabdominal source of infection. It is now internationally agreed that a polymorphonuclear (PMN) cell count in the ascitic fluid of over 250 ...

  19. Spontaneous dimensional reduction?

    Science.gov (United States)

    Carlip, Steven

    2012-10-01

    Over the past few years, evidence has begun to accumulate suggesting that spacetime may undergo a "spontaneous dimensional reduction" to two dimensions near the Planck scale. I review some of this evidence, and discuss the (still very speculative) proposal that the underlying mechanism may be related to short-distance focusing of light rays by quantum fluctuations.

  20. Exploiting the spontaneous potential of the electrodes used in the capacitive mixing technique for the extraction of energy from salinity difference

    NARCIS (Netherlands)

    Brogioli, D.; Ziano, R.; Rica, R.A.; Salerno, D.; Kozynchenko, O.; Hamelers, H.V.M.; Mantegazza, F.

    2012-01-01

    The "capacitive mixing" (CAPMIX) technique is aimed at the extraction of energy from the salinity difference between the sea and rivers. It is based on the voltage rise that takes place at the electrodes when changing the salt concentration of the solution in which the two electrodes are dipped. In

  1. Allegheny County Toxics Release Inventory

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The Toxics Release Inventory (TRI) data provides information about toxic substances released into the environment or managed through recycling, energy recovery, and...

  2. Tech-X Corporation releases simulation code for solving complex problems in plasma physics : VORPAL code provides a robust environment for simulating plasma processes in high-energy physics, IC fabrications and material processing applications

    CERN Multimedia

    2005-01-01

    Tech-X Corporation releases simulation code for solving complex problems in plasma physics : VORPAL code provides a robust environment for simulating plasma processes in high-energy physics, IC fabrications and material processing applications

  3. Research into releasing inorganic phosphate and base from 5'-dTMP irradiated by a low energy ion beam

    International Nuclear Information System (INIS)

    Shao Chunlin; Yu Zengliang

    1994-01-01

    Research into radiation damage of nucleotide is an important area in radiation biology. In this paper, the yield of inorganic phosphate and base released from 5'-dTMP irradiated by a 30 keV N + ion beam was investigated in several aspects. The effect of particle fluence on yield and the influence of treatment with 0.1 N NaOH was deduced. By analysis, it is known that the alkali treatment not only increases the yield of inorganic phosphate, but also damages and splits the base released from irradiated 5'-dTMP. When the irradiated samples are treated by 0.1 N NaOH immediately, the yield of inorganic phosphate is increased by a factor of 1.7 and the concentration of base decreased to half of the original value. But the yield of inorganic phosphate could be increased by a factor of 2.8 after 40 min of alkali treatment. On the other hand, when 5'dTMP was irradiated by the ion beam, the G(Pi) obtained was above 0.44, higher than with γ-radiation. (Author)

  4. The VAK of vacuum fluctuation, Spontaneous self-organization and complexity theory interpretation of high energy particle physics and the mass spectrum

    International Nuclear Information System (INIS)

    El Naschie, M.S.

    2003-01-01

    The paper is a rather informal introduction to the concepts and results of the E-infinity Cantorian theory of quantum physics. The fundamental tools of complexity theory and non-linear dynamics (Hausdorff dimensions, fat fractals, etc.) are used to give what we think to be a new interpretation of high energy physics and to determine the corresponding mass-spectrum. Particular attention is paid to the role played by the VAK, KAM theorem, Arnold diffusion, Newhaus sinks and knot theory in determining the stability of an elementary 'particle-wave' which emerges in self-organizatory manner out of sizzling vacuum fluctuation

  5. Spontaneous healing of spontaneous coronary artery dissection.

    Science.gov (United States)

    Almafragi, Amar; Convens, Carl; Heuvel, Paul Van Den

    2010-01-01

    Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome and sudden cardiac death. It should be suspected in every healthy young woman without cardiac risk factors, especially during the peripartum or postpartum periods. It is important to check for a history of drug abuse, collagen vascular disease or blunt trauma of the chest. Coronary angiography is essential for diagnosis and early management. We wonder whether thrombolysis might aggravate coronary dissection. All types of treatment (medical therapy, percutaneous intervention or surgery) improve the prognosis without affecting survival times if used appropriately according to the clinical stability and the angiographic features of the involved coronary arteries. Prompt recognition and targeted treatment improve outcomes. We report a case of SCAD in a young female free of traditional cardiovascular risk factors, who presented six hours after thrombolysis for ST elevation myocardial infarction. Coronary angiography showed a dissection of the left anterior descending and immediate branch. She had successful coronary artery bypass grafting, with complete healing of left anterior descending dissection.

  6. Release of systems, plant components and buildings from restrictions under the Nuclear Energy Act; Entlassung von Systemen und Anlagenteilen des Ueberwachungsbereiches aus dem Geltungsbereich des Atomgesetzes

    Energy Technology Data Exchange (ETDEWEB)

    Simic, S. [Arithmetik Umwelt- und Hygienekonzepte, Strahlenschutz, Kleinostheim (Germany); Mohrmann, W. [RWE Power AG, Kraftwerk Muelheim-Kaerlich (Germany)

    2003-07-01

    Firstly, radioactive substances released in accordance with Art. 29 StrlSchV are ''non-radioactive'' by definition. Secondly, the free-release threshold limits listed there are computed on the basis of the ''10-{mu}Sv concept''. It is important to remember in this context that all reputable international radiation safety organizations classify personal dosage levels within a range of several times 10 {mu}Sv per year as ''trivial dosages'' below which it is safe to assume that the potential risk is negligible. In keeping with this internationally recognized scientific standard, we contend that a radioactivity threshold value between 10% and one-half of the free-release thresholds limits cited above (e.g. 0.5 Bq/cm{sup 2} or 0.05 Bq/g in the case of {sup 60} Co) ensures a sufficient degree of radiation safety. In addition, sampling methods to be used in measuring surface radioactivity are to be specified for the purpose of establishing evidence. The following sections describe in detail the formal procedures proposed for use in the decommissioning the Muelheim-Kaerlich power plant, some of which have already been carried out. One of the most significant problems encountered in this context is that of responding appropriately to continual changes in radiation safety regulations resulting from revision of the Nuclear Energy Act and the Radiation Safety Directive. (orig.)

  7. Tryptophan availability modulates serotonin release from rat hypothalamic slices

    Science.gov (United States)

    Schaechter, Judith D.; Wurtman, Richard J.

    1989-01-01

    The relationship between the tryptophan availability and serononin release from rat hypothalamus was investigated using a new in vitro technique for estimating rates at which endogenous serotonin is released spontaneously or upon electrical depolarization from hypothalamic slices superfused with a solution containing various amounts of tryptophan. It was found that the spontaneous, as well as electrically induced, release of serotonin from the brain slices exhibited a dose-dependent relationship with the tryptophan concentration of the superfusion medium.

  8. Spontaneous fission of the heaviest elements

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, D.C.

    1989-04-01

    Although spontaneous fission was discovered in /sup 238/U in 1940, detailed studies of the process were first made possible in the 1960's with the availability of milligram quantities of /sup 252/Cf. The advent of solid-state detectors made it possible to perform measurements of coincident fission fragments from even very short-lived spontaneous fission activities or those available in only very small quantities. Until 1971 it was believed that the main features of the mass and kinetic-energy distributions were essentially the same as those for thermal neutron-induced fission and that all low-energy fission proceeded via asymmetric mass division with total kinetic energies which could be derived by linear extrapolation from those of lighter elements. In 1971, measurements of /sup 257/Fm showed an increase in symmetric mass division with anomalously high TKE's. Subsequent experiments showed that in /sup 258/Fm and /sup 259/Fm, the most probable mass split was symmetric with very high total kinetic energy. Measurements for the heavier elements have shown symmetric mass distributions with both high and low total kinetic energies. Recent results for spontaneous fission properties of the heaviest elements are reviewed and compared with theory. 31 refs., 8 figs., 1 tab.

  9. Spontaneous spinal epidural abscess.

    LENUS (Irish Health Repository)

    Ellanti, P

    2011-10-01

    Spinal epidural abscess is an uncommon entity, the frequency of which is increasing. They occur spontaneously or as a complication of intervention. The classical triad of fever, back pain and neurological symptoms are not always present. High index of suspicion is key to diagnosis. Any delay in diagnosis and treatment can have significant neurological consequences. We present the case of a previously well man with a one month history of back pain resulting from an epidural abscess.

  10. Quantum-kinetic modeling of electron release in low-energy surface collisions of atoms and molecules

    Energy Technology Data Exchange (ETDEWEB)

    Marbach, Johannes

    2012-09-20

    In this work we present a theoretical description of electron release in the collision of atomic and molecular projectiles with metallic and especially dielectric surfaces. The associated electron yield, the secondary electron emission coefficient, is an important input parameter for numerical simulations of dielectric barrier discharges and other bounded low-temperature gas discharges. The available reference data for emission coefficients is, however, very sparse and often uncertain, especially for molecular projectiles. With the present work we aim to contribute to the filling of these gaps by providing a flexible and easy-to-use model that allows for a convenient calculation of the emission coefficient and related quantities for a wide range of projectile-surface systems and the most dominant reaction channels.

  11. Silica-Based and Borate-Based, Titania-Containing Bioactive Coatings Characterization: Critical Strain Energy Release Rate, Residual Stresses, Hardness, and Thermal Expansion

    Directory of Open Access Journals (Sweden)

    Omar Rodriguez

    2016-12-01

    Full Text Available Silica-based and borate-based glass series, with increasing amounts of TiO2 incorporated, are characterized in terms of their mechanical properties relevant to their use as metallic coating materials. It is observed that borate-based glasses exhibit CTE (Coefficient of Thermal Expansion closer to the substrate’s (Ti6Al4V CTE, translating into higher mode I critical strain energy release rates of glasses and compressive residual stresses and strains at the coating/substrate interface, outperforming the silica-based glasses counterparts. An increase in the content of TiO2 in the glasses results in an increase in the mode I critical strain energy release rate for both the bulk glass and for the coating/substrate system, proving that the addition of TiO2 to the glass structure enhances its toughness, while decreasing its bulk hardness. Borate-based glass BRT3, with 15 mol % TiO2 incorporated, exhibits superior properties overall compared to the other proposed glasses in this work, as well as 45S5 Bioglass® and Pyrex.

  12. Final Report: Safety of Plasma-Facing Components and Aerosol Transport During Hard Disruptions and Accidental Energy Release in Fusion Reactor

    International Nuclear Information System (INIS)

    Bourham, Mohamed A.; Gilligan, John G.

    1999-01-01

    Safety considerations in large future fusion reactors like ITER are important before licensing the reactor. Several scenarios are considered hazardous, which include safety of plasma-facing components during hard disruptions, high heat fluxes and thermal stresses during normal operation, accidental energy release, and aerosol formation and transport. Disruption events, in large tokamaks like ITER, are expected to produce local heat fluxes on plasma-facing components, which may exceed 100 GW/m 2 over a period of about 0.1 ms. As a result, the surface temperature dramatically increases, which results in surface melting and vaporization, and produces thermal stresses and surface erosion. Plasma-facing components safety issues extends to cover a wide range of possible scenarios, including disruption severity and the impact of plasma-facing components on disruption parameters, accidental energy release and short/long term LOCA's, and formation of airborne particles by convective current transport during a LOVA (water/air ingress disruption) accident scenario. Study, and evaluation of, disruption-induced aerosol generation and mobilization is essential to characterize database on particulate formation and distribution for large future fusion tokamak reactor like ITER. In order to provide database relevant to ITER, the SIRENS electrothermal plasma facility at NCSU has been modified to closely simulate heat fluxes expected in ITER

  13. Nuclear reactor for release of nuclear energy, without a chain reaction using the simultaneous implosion of three, or more, atomic nuclei

    International Nuclear Information System (INIS)

    Pedrick, A.P.

    1976-01-01

    A modified form of what is known as a 'streaking nuclear reactor' is described. In this type of reactor it is proposed to obtain release of nuclear energy from atomic nuclei by stripping such nuclei of their electron clouds or shells, to form a high temperature plasma, and breaking nucleons off the surface of the nuclei. In the apparatus described it is proposed to break up nuclei by causing three or more nuclei to collide with each other at very high velocity. Streams of nuclei, stripped of their electron clouds are directed into a reactor vessel to a focal point or implosion center along three or more ducts, equi-angularly spaced around the implosion center in the same plane, the arrangement being such as to permit mutual simultaneous collision of three or more of the nuclei. The importance of achieving a release of nuclear energy in this manner is that it may be able to use any chemical element that can be converted to a plasma, but it is most likely to be successful with elements of high atomic number, such as Pb or Bi. (U.K.)

  14. Recent Advances in Nanoparticle-Based Förster Resonance Energy Transfer for Biosensing, Molecular Imaging and Drug Release Profiling

    Directory of Open Access Journals (Sweden)

    Nai-Tzu Chen

    2012-12-01

    Full Text Available Förster resonance energy transfer (FRET may be regarded as a “smart” technology in the design of fluorescence probes for biological sensing and imaging. Recently, a variety of nanoparticles that include quantum dots, gold nanoparticles, polymer, mesoporous silica nanoparticles and upconversion nanoparticles have been employed to modulate FRET. Researchers have developed a number of “visible” and “activatable” FRET probes sensitive to specific changes in the biological environment that are especially attractive from the biomedical point of view. This article reviews recent progress in bringing these nanoparticle-modulated energy transfer schemes to fruition for applications in biosensing, molecular imaging and drug delivery.

  15. The WiggleZ Dark Energy Survey: final data release and the metallicity of UV-luminous galaxies

    Science.gov (United States)

    Drinkwater, Michael J.; Byrne, Zachary J.; Blake, Chris; Glazebrook, Karl; Brough, Sarah; Colless, Matthew; Couch, Warrick; Croton, Darren J.; Croom, Scott M.; Davis, Tamara M.; Forster, Karl; Gilbank, David; Hinton, Samuel R.; Jelliffe, Ben; Jurek, Russell J.; Li, I.-hui; Martin, D. Christopher; Pimbblet, Kevin; Poole, Gregory B.; Pracy, Michael; Sharp, Rob; Smillie, Jon; Spolaor, Max; Wisnioski, Emily; Woods, David; Wyder, Ted K.; Yee, Howard K. C.

    2018-03-01

    The WiggleZ Dark Energy Survey measured the redshifts of over 200 000 ultraviolet (UV)-selected (NUV UV-luminous Lyman-break galaxies by stacking the spectra in bins of luminosity, redshift, and stellar mass. The most luminous (-25 magUV-luminous WiggleZ galaxies.

  16. Comparative effects of TV watching, recreational computer use, and sedentary video game play on spontaneous energy intake in male children. A randomised crossover trial.

    Science.gov (United States)

    Marsh, Samantha; Ni Mhurchu, Cliona; Jiang, Yannan; Maddison, Ralph

    2014-06-01

    To compare the effects of three screen-based sedentary behaviours on acute energy intake (EI) in children. Normal-weight males aged 9-13 years participated in a randomised crossover trial conducted in a laboratory setting between November 2012 and February 2013 in Auckland, New Zealand. EI during an ad libitum meal was compared for three 1-hour conditions: (1) television (TV) watching, (2) sedentary video game (VG) play, and (3) recreational computer use. The primary endpoint was total EI from food and drink. Mixed regression models were used to evaluate the treatment conditions adjusting for age, BMI, and appetite at baseline. A total of 20 participants were randomised and all completed the three conditions. Total EI from food and drink in the TV, computer, and VG conditions was estimated at 820 (SE 73.15), 685 (SE 73.33), and 696 (SE 73.16) kcal, respectively, with EI being significantly greater in the TV versus computer condition (+135; P = 0.04), a trend towards greater intake in the TV versus VG condition (+124; P = 0.06), but not significantly different between the computer and VG conditions (-10; P = 0.87). TV watching was associated with greater EI compared with computer use, and a trend towards greater EI compared with VG play. Copyright © 2014. Published by Elsevier Ltd.

  17. Spontaneous Tumour Lysis Syndrome in a Multiple Myeloma

    Directory of Open Access Journals (Sweden)

    Can Huzmeli

    2016-01-01

    Full Text Available The tumor lysis syndrome (TLS is a collection of metabolic abnormalities that occur in consequence of the release of intracellular contents following lysis of tumor cells. TLS occurs spontaneously or after chemotherapy. Spontaneous TLS is uncommon occurrence in multiple myeloma (MM. We define a case of a 70-year-old woman patient who was found to have MM with spontaneous TLS, following a compression fracture of the T-12 vertebrae. While serum uric acid and phosphorous levels were high, low calcium levels were identified. There were also acute kidney injury and metabolic acidosis. Upon the diagnosis of TLS, she was treated with hydration, allopurinol, sodium bicarbonate, and calcium gluconate. The improvement of her laboratory data was observed. We submitted this case in order to draw attention to the presentation of MM with spontaneous TLS.

  18. Spontaneous Thigh Compartment Syndrome

    Directory of Open Access Journals (Sweden)

    Khan, Sameer K

    2011-02-01

    Full Text Available A young man presented with a painful and swollen thigh, without any history of trauma, illness, coagulopathic medication or recent exertional exercise. Preliminary imaging delineated a haematoma in the anterior thigh, without any fractures or muscle trauma. Emergent fasciotomies were performed. No pathology could be identified intra-operatively, or on follow-up imaging. A review of thigh compartment syndromes described in literature is presented in a table. Emergency physicians and traumatologists should be cognisant of spontaneous atraumatic presentations of thigh compartment syndrome, to ensure prompt referral and definitive management of this limb-threatening condition. [West J Emerg Med. 2011;12(1:134-138].

  19. The Effects of the SUN Project on Teacher Knowledge and Self-Efficacy regarding Biological Energy Transfer Are Significant and Long-Lasting: Results of a Randomized Controlled Trial

    Science.gov (United States)

    Batiza, Ann Finney; Gruhl, Mary; Zhang, Bo; Harrington, Tom; Roberts, Marisa; LaFlamme, Donna; Haasch, Mary Anne; Knopp, Jonathan; Vogt, Gina; Goodsell, David; Hagedorn, Eric; Marcey, David; Hoelzer, Mark; Nelson, Dave

    2013-01-01

    Biological energy flow has been notoriously difficult to teach. Our approach to this topic relies on abiotic and biotic examples of the energy released by moving electrons in thermodynamically spontaneous reactions. A series of analogical model-building experiences was supported with common language and representations including manipulatives.…

  20. Estimating trace gas and aerosol emissions over South America: Relationship between fire radiative energy released and aerosol optical depth observations

    Science.gov (United States)

    Pereira, Gabriel; Freitas, Saulo R.; Moraes, Elisabete Caria; Ferreira, Nelson Jesus; Shimabukuro, Yosio Edemir; Rao, Vadlamudi Brahmananda; Longo, Karla M.

    2009-12-01

    Contemporary human activities such as tropical deforestation, land clearing for agriculture, pest control and grassland management lead to biomass burning, which in turn leads to land-cover changes. However, biomass burning emissions are not correctly measured and the methods to assess these emissions form a part of current research area. The traditional methods for estimating aerosols and trace gases released into the atmosphere generally use emission factors associated with fuel loading and moisture characteristics and other parameters that are hard to estimate in near real-time applications. In this paper, fire radiative power (FRP) products were extracted from Moderate Resolution Imaging Spectroradiometer (MODIS) and from the Geostationary Operational Environmental Satellites (GOES) fire products and new South America generic biomes FRE-based smoke aerosol emission coefficients were derived and applied in 2002 South America fire season. The inventory estimated by MODIS and GOES FRP measurements were included in Coupled Aerosol-Tracer Transport model coupled to the Brazilian developments on the Regional Atmospheric Modeling System (CATT-BRAMS) and evaluated with ground truth collected in Large Scale Biosphere-Atmosphere Smoke, Aerosols, Clouds, rainfall, and Climate (SMOCC) and Radiation, Cloud, and Climate Interactions (RaCCI). Although the linear regression showed that GOES FRP overestimates MODIS FRP observations, the use of a common external parameter such as MODIS aerosol optical depth product could minimize the difference between sensors. The relationship between the PM 2.5μm (Particulate Matter with diameter less than 2.5 μm) and CO (Carbon Monoxide) model shows a good agreement with SMOCC/RaCCI data in the general pattern of temporal evolution. The results showed high correlations, with values between 0.80 and 0.95 (significant at 0.5 level by student t test), for the CATT-BRAMS simulations with PM 2.5μm and CO.

  1. Spontaneous Tumor Lysis Syndrome

    Directory of Open Access Journals (Sweden)

    Alicia C. Weeks MD

    2015-08-01

    Full Text Available Tumor lysis syndrome (TLS is a known complication of malignancy and its treatment. The incidence varies on malignancy type, but is most common with hematologic neoplasms during cytotoxic treatment. Spontaneous TLS is thought to be rare. This case study is of a 62-year-old female admitted with multisystem organ failure, with subsequent diagnosis of aggressive B cell lymphoma. On admission, laboratory abnormalities included renal failure, elevated uric acid (20.7 mg/dL, and 3+ amorphous urates on urinalysis. Oliguric renal failure persisted despite aggressive hydration and diuretic use, requiring initiation of hemodialysis prior to chemotherapy. Antihyperuricemic therapy and hemodialysis were used to resolve hyperuricemia. However, due to multisystem organ dysfunction syndrome with extremely poor prognosis, the patient ultimately expired in the setting of a terminal ventilator wean. Although our patient did not meet current TLS criteria, she required hemodialysis due to uric acid nephropathy, a complication of TLS. This poses the clinical question of whether adequate diagnostic criteria exist for spontaneous TLS and if the lack of currently accepted guidelines has resulted in the underestimation of its incidence. Allopurinol and rasburicase are commonly used for prevention and treatment of TLS. Although both drugs decrease uric acid levels, allopurinol mechanistically prevents formation of the substrate rasburicase acts to solubilize. These drugs were administered together in our patient, although no established guidelines recommend combined use. This raises the clinical question of whether combined therapy is truly beneficial or, conversely, detrimental to patient outcomes.

  2. Quantifying the mode II critical strain energy release rate of borate bioactive glass coatings on Ti6Al4V substrates.

    Science.gov (United States)

    Matinmanesh, A; Li, Y; Clarkin, O; Zalzal, P; Schemitsch, E H; Towler, M R; Papini, M

    2017-11-01

    Bioactive glasses have been used as coatings for biomedical implants because they can be formulated to promote osseointegration, antibacterial behavior, bone formation, and tissue healing through the incorporation and subsequent release of certain ions. However, shear loading on coated implants has been reported to cause the delamination and loosening of such coatings. This work uses a recently developed fracture mechanics testing methodology to quantify the critical strain energy release rate under nearly pure mode II conditions, G IIC , of a series of borate-based glass coating/Ti6Al4V alloy substrate systems. Incorporating increasing amounts of SrCO 3 in the glass composition was found to increase the G IIC almost twofold, from 25.3 to 46.9J/m 2 . The magnitude and distribution of residual stresses in the coating were quantified, and it was found that the residual stresses in all cases distributed uniformly over the cross section of the coating. The crack was driven towards, but not into, the glass/Ti6Al4V substrate interface due to the shear loading. This implied that the interface had a higher fracture toughness than the coating itself. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Gamma ray transitions in de-excitation of 252Cf spontaneous fission fragments

    International Nuclear Information System (INIS)

    Khan, N.A.; Rashid, K.; Ahmad, M.; Qureshi, I.E.; Alam, G.D.; Ali, A.; Bhatti, N.; Horsch, F.

    1983-11-01

    Gamma rays in the range from 60 keV to 730 keV have been observed following the spontaneous fission of 252 Cf, with high resolution Ge(Li) detector, full width at half maximum (FWHM) of 700 eV at 122 keV, in coincidence with the two fission fragments observed with surface barrier detectors. A total number of 18, 636, 549 events were recorded over a run period of about 150 hours stretching over three weeks. The events were sorted to generate gamma ray spectra belonging to 2 amu intervals gamma of the fragment masses and 6 MeV intervals of the total kinetic energy released. Some of the prominent gamma lines belonging to various masses of the fission fragments have been identified. For some gamma lines, the intensities have been evaluated as a function of the total kinetic energy of the fission fragments. (authors)

  4. Energy release of the 2013 M(w) 8.3 Sea of Okhotsk earthquake and deep slab stress heterogeneity.

    Science.gov (United States)

    Ye, Lingling; Lay, Thorne; Kanamori, Hiroo; Koper, Keith D

    2013-09-20

    Earth's deepest earthquakes occur in subducting oceanic lithosphere, where temperatures are lower than in ambient mantle. On 24 May 2013, a magnitude 8.3 earthquake ruptured a 180-kilometer-long fault within the subducting Pacific plate about 609 kilometers below the Sea of Okhotsk. Global seismic P wave recordings indicate a radiated seismic energy of ~1.5 × 10(17) joules. A rupture velocity of ~4.0 to 4.5 kilometers/second is determined by back-projection of short-period P waves, and the fault width is constrained to give static stress drop estimates (~12 to 15 megapascals) compatible with theoretical radiation efficiency for crack models. A nearby aftershock had a stress drop one to two orders of magnitude higher, indicating large stress heterogeneity in the deep slab, and plausibly within the rupture process of the great event.

  5. Supplemental Release Limits for the Directed Reuse of Lead in Shielding Products by the Department of Energy

    Energy Technology Data Exchange (ETDEWEB)

    Coleman, R.L.

    2001-08-22

    The DOE National Center of Excellence for Metals Recycle (NMR) proposes to define and implement a complex-wide directed reuse strategy for surplus radiologically impacted lead (Pb) as part of the U.S. Department of Energy's commitment to the safe and cost-effective recycle or reuse of excess materials and equipment across the DOE complex. NMR will, under this proposal, act on behalf of the DOE Office of Environmental Management, Office of Technical Program Integration (specifically EM-22), as the Department's clearinghouse for DOE surplus lead and lead products by developing and maintaining a cost-effective commercially-based contaminated lead recycle program. It is NMR's intention, through this directed reuse strategy, to mitigate the adverse environmental and economic consequences of managing surplus lead as a waste within the complex. This approach would promote the safe and cost-effective reuse of DOE's scrap and surplus lead in support of the Department's goals of resource utilization, energy conservation, pollution prevention and waste minimization. This report discusses recommendations for supplemental radiological limits for the directed reuse of contaminated lead and lead products by the DOE within the nuclear industry. The limits were selected--with slight modification--from the recently published American National Standards Institute and Health Physics Society standard N13.12 titled Surface and Volume Radioactivity Standards for Clearance (ANSI/HPS 1999) and are being submitted for formal approval by the DOE. Health and measurement implications from the adoption and use of the limits for directed reuse scenarios are discussed within this report.

  6. Electromagnetic Energy Released in the Subduction (Benioff) Zone in Weeks Previous to Earthquake Occurrence in Central Peru and the Estimation of Earthquake Magnitudes.

    Science.gov (United States)

    Heraud, J. A.; Centa, V. A.; Bleier, T.

    2017-12-01

    During the past four years, magnetometers deployed in the Peruvian coast have been providing evidence that the ULF pulses received are indeed generated at the subduction or Benioff zone and are connected with the occurrence of earthquakes within a few kilometers of the source of such pulses. This evidence was presented at the AGU 2015 Fall meeting, showing the results of triangulation of pulses from two magnetometers located in the central area of Peru, using data collected during a two-year period. Additional work has been done and the method has now been expanded to provide the instantaneous energy released at the stress areas on the Benioff zone during the precursory stage, before an earthquake occurs. Collected data from several events and in other parts of the country will be shown in a sequential animated form that illustrates the way energy is released in the ULF part of the electromagnetic spectrum. The process has been extended in time and geographical places. Only pulses associated with the occurrence of earthquakes are taken into account in an area which is highly associated with subduction-zone seismic events and several pulse parameters have been used to estimate a function relating the magnitude of the earthquake with the value of a function generated with those parameters. The results shown, including the animated data video, constitute additional work towards the estimation of the magnitude of an earthquake about to occur, based on electromagnetic pulses that originated at the subduction zone. The method is providing clearer evidence that electromagnetic precursors in effect conveys physical and useful information prior to the advent of a seismic event

  7. 7. annual Energy-Info barometer on market opening, performed by the national mediator of energy and the Commission for energy regulation. 7. release of the annual Energy-Info barometer on market opening

    International Nuclear Information System (INIS)

    Lefeuvre, Katia; Monteil, Anne

    2013-11-01

    This publication comments the results of a survey on the relationship between French people and energy. It first outlines that energy consumption remains a strong matter of concern (people pay attention to the use of heating in winter, are aware of the existence of social tariffs, and gave their opinion about the quality of information about their consumption), and that people seem interested in a system with tariffs only based on consumption. The survey showed that people are always more aware of the possibility to change their provider, but that rules induced by this market opening are not well integrated yet (the definition of regulated tariffs is mainly unknown). It appears that this market opening is positively perceived but without perception of actual benefits on tariffs. A part of the survey assessed how well the mediator was known. A shorter text proposes a synthetic report on the survey with a focus on some key figures

  8. EIA new releases

    International Nuclear Information System (INIS)

    1994-12-01

    This report was prepared by the Energy Information Administration. It contains news releases on items of interest to the petroleum, coal, nuclear, electric and alternate fuels industries ranging from economic outlooks to environmental concerns. There is also a listing of reports by industry and an energy education resource listing containing sources for free or low-cost energy-related educational materials for educators and primary and secondary students

  9. Spontaneous Intracranial Hypotension

    International Nuclear Information System (INIS)

    Joash, Dr.

    2015-01-01

    Epidemiology is not only rare but an important cause of new daily persistent headaches among young & middle age individuals. The Etiology & Pathogenesis is generally caused by spinal CSF leak. Precise cause remains largely unknown, underlying structural weakness of spinal meninges is suspected. There are several MR Signs of Intracranial Hypotension that include:- diffuse pachymeningeal (dural) enhancement; bilateral subdural, effusion/hematomas; Downward displacement of brain; enlargement of pituitary gland; Engorgement of dural venous sinuses; prominence of spinal epidural venous plexus and Venous sinus thrombosis & isolated cortical vein thrombosis. The sum of volumes of intracranial blood, CSF & cerebral tissue must remain constant in an intact cranium. Treatment in Many cases can be resolved spontaneously or by use Conservative approach that include bed rest, oral hydration, caffeine intake and use of abdominal binder. Imaging Modalities for Detection of CSF leakage include CT myelography, Radioisotope cisternography, MR myelography, MR imaging and Intrathecal Gd-enhanced MR

  10. Spontaneous wave packet reduction

    International Nuclear Information System (INIS)

    Ghirardi, G.C.

    1994-06-01

    There are taken into account the main conceptual difficulties met by standard quantum mechanics in dealing with physical processes involving macroscopic system. It is stressed how J.A.Wheeler's remarks and lucid analysis have been relevant to pinpoint and to bring to its extreme consequences the puzzling aspects of quantum phenomena. It is shown how the recently proposed models of spontaneous dynamical reduction represent a consistent way to overcome the conceptual difficulties of the standard theory. Obviously, many nontrivial problems remain open, the first and more relevant one being that of generalizing the model theories considered to the relativistic case. This is the challenge of the dynamical reduction program. 43 refs, 2 figs

  11. Two component silicone modified epoxy foul release coatings: Effect of modulus, surface energy and surface restructuring on pseudobarnacle and macrofouling behavior

    International Nuclear Information System (INIS)

    Rath, S.K.; Chavan, J.G.; Sasane, Savita; Jagannath; Patri, M.; Samui, A.B.; Chakraborty, B.C.

    2010-01-01

    Two component silicone modified epoxy resin based low surface energy and non-toxic foul release coatings were developed. Silicone modified epoxy resin with 15 and 30% silicone content was used as component A and a polyether diamine (Jeffamine-500) was used as the component B. Free standing films were prepared by casting a mixture of components A and B in stoichiometric proportions. The surface composition, surface topography and wetting properties of the coatings were studied by angle resolved X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM) and contact angle goniometry respectively. The mechanical properties of the cured films were evaluated by tensile measurements as well as dynamic mechanical analysis. Pseudobarnacles made of aluminium studs were attached to the coated panels and adhesion tests were carried out by a pseudobarnacle tester. Coated panels were exposed in Mumbai harbor for fouling studies for a period of 90 days. Surface restructuring studies of the coatings upon immersion in seawater were carried out by measuring the changes in advancing and receding contact angles by contact angle goniometry. The effect of surface energy, modulus and surface restructuring of the coatings on the macrofouling and pseudobarnacle adhesion properties has been discussed in detail.

  12. The Sloan Digital Sky Survey Quasar Lens Search. III Constraints on Dark Energy From The Third Data Release Quasar Lens Catalog

    Energy Technology Data Exchange (ETDEWEB)

    Oguri, M; Inada, N; Strauss, M A; Kochanek, C S; Richards, G T; Schneider, D P; Becker, R H; Fukugita, M; Gregg, M D; Hall, P B; Hennawi, J F; Johnston, D E; Kayo, I; Keeton, C R; Pindor, B; Shin, M; Turner, E; White, R L; York, D G; Anderson, S F; Bahcall, N A; Brunner, R J; Burles, S; Castander, F J; Chiu, K; Clocchiatti, A; Einsenstein, D; Frieman, J; Kawano, Y; Lupton, R; Morokuma, T; Rix, H; Scranton, R; Sheldon, E S

    2007-09-12

    We present cosmological results from the statistics of lensed quasars in the Sloan Digital Sky Survey (SDSS) Quasar Lens Search. By taking proper account of the selection function, we compute the expected number of quasars lensed by early-type galaxies and their image separation distribution assuming a flat universe, which is then compared with 7 lenses found in the SDSS Data Release 3 to derive constraints on dark energy under strictly controlled criteria. For a cosmological constant model (w = -1) we obtain {Omega}{sub {Lambda}} = 0.74{sub -0.15}{sup +0.11}(stat.){sub -0.06}{sup +0.13}(syst.). Allowing w to be a free parameter we find {Omega}{sub M} = 0.26{sub -0.06}{sup +0.07}(stat.){sub -0.05}{sup +0.03}(syst.) and w = -1.1 {+-} 0.6(stat.){sub -0.5}{sup +0.3}(syst.) when combined with the constraint from the measurement of baryon acoustic oscillations in the SDSS luminous red galaxy sample. Our results are in good agreement with earlier lensing constraints obtained using radio lenses, and provide additional confirmation of the presence of dark energy consistent with a cosmological constant, derived independently of type Ia supernovae.

  13. Spontaneous compactification to homogeneous spaces

    International Nuclear Information System (INIS)

    Mourao, J.M.

    1988-01-01

    The spontaneous compactification of extra dimensions to compact homogeneous spaces is studied. The methods developed within the framework of coset space dimensional reduction scheme and the most general form of invariant metrics are used to find solutions of spontaneous compactification equations

  14. Screening for spontaneous preterm birth

    NARCIS (Netherlands)

    van Os, M.A.; van Dam, A.J.E.M.

    2015-01-01

    Preterm birth is the most important cause of perinatal morbidity and mortality worldwide. In this thesis studies on spontaneous preterm birth are presented. The main objective was to investigate the predictive capacity of mid-trimester cervical length measurement for spontaneous preterm birth in a

  15. Spontaneous Pneumomediastinum: Hamman Syndrome

    Directory of Open Access Journals (Sweden)

    Tushank Chadha, BS

    2018-04-01

    significant fat stranding. The image also showed an intraluminal stent traversing the gastric antrum and gastric pylorus with no indication of obstruction. Circumferential mural thickening of the gastric antrum and body were consistent with the patient’s history of gastric adenocarcinoma. The shotty perigastric lymph nodes with associated fat stranding, along the greater curvature of the distal gastric body suggested local regional nodal metastases and possible peritoneal carcinomatosis. The thoracic CT scans showed extensive pneumomediastinum that tracked into the soft tissues of the neck, which given the history of vomiting also raised concern for esophageal perforation. There was still no evidence of mediastinal abscess or fat stranding. Additionally, a left subclavian vein port catheter, which terminates with tip at the cavoatrial junction of the superior vena cava can also be seen on the image. Discussion: Spontaneous Pneumomediastinum, also known as Hamman syndrome, is defined by the uncommon incidence of free air in the mediastinum due to the bursting of alveoli, as a result of extended spells of shouting, coughing, or vomiting.1,2 The condition is diagnosed when a clear cause (aerodigestive rupture, barotrauma, infection secondary to gas-forming organisms3 for pneumomediastinum cannot be clearly identified on diagnostic studies. Macklin and Macklin were the first to note the pathogenesis of the syndrome and explained that the common denominator to spontaneous pneumomediastinum was that increased alveolar pressure leads to alveolar rupture.3 Common clinical findings for spontaneous pneumomediastinum include: chest pain, dyspnea, cough, and emesis.4 The condition is not always readily recognized on initial presentation in part for its rare incidence, estimated to be approximately 1 in every 44,500 ED patients3and also because of the non-specific presenting symptoms. For this patient, there was no clear singular cause, and therefore she received care for spontaneous

  16. Overview of renewable energies in Lorraine - Assessment: Year 2013. Situation note on renewable energies in Lorraine - Assessment: first half 2014, 2nd half 2014. Overview of renewable energies in the Grand East region - Assessment year 2015-release 2016. Overview of renewable and recovery energies in the Grand East region - Assessment year 2016-release 2017

    International Nuclear Information System (INIS)

    2015-02-01

    A first document proposes an overview of the development of renewable energies in Lorraine with respect to regional as well as European and national objectives defined for each renewable energy type. Annual data for 2013 are herein presented. Graphs indicate values for the share of renewable energies, the energy mix in Lorraine, locations, evolutions and levels of production for the different renewable sources (wind, photovoltaic, hydroelectricity, methanization, wood energy, geothermal and heat pumps, solar thermal, waste valorisation, bio-fuels). The second and third documents propose assessments and comments of situations and evolutions of productions and development (actions, regulatory and legal context, projects) for the different sources, an assessment of the implementation progress of the regional scheme of connection of renewable energies. Annual publications are then proposed which give the same kind of assessments, and comparisons with other French regions

  17. Gadolinium released from MR contrast agents is deposited in brain tumors: in situ demonstration using scanning electron microscopy with energy dispersive X-ray spectroscopy

    International Nuclear Information System (INIS)

    Xia, Daniel; Davis, Richard L.; Crawford, Judith A.; Abraham, Jerrold L.

    2010-01-01

    Background: Gadolinium (Gd)-containing MRI contrast agents (GdCA) are widely used in studies of brain tumors, and a number of reports suggest that under certain conditions, such as renal failure, Gd may be released from GdCA into patient's tissues. Whether this may happen in abnormal tissues in the absence of renal failure has not been studied. Purpose: To test the hypothesis that the local retention of GdCA resulting from brain tumor-associated alterations in the blood-brain barrier (BBB) may result in the deposition of Gd released from the GdCA, depending on stability. Material and Methods: In this retrospective study, 30 selected brain tumor biopsies from 28 patients (taken before and after an institutional switch from a less stable to an intermediate stable GdCA) were searched for Gd-containing deposits using scanning electron microscopy/energy dispersive X-ray spectroscopy (SEM/EDS). Relevant histories and laboratory results were obtained through institutional electronic records. Associations between the presence of deposits and other variables were tested for statistical significance using the two-tailed Fisher's exact test. Results: Insoluble deposits containing Gd associated with phosphorus and calcium were found in seven biopsies from five patients. These deposits were found in patients with estimated GFRs above 53 ml/min, and were detected more often in those receiving GdCA before the switch from a less stable to an intermediate stable GdCA (P = 0.04), and may be more frequent in patients receiving more than one contrast-enhanced MR scan (P = 0.15). Conclusion: Gd-containing deposits are present in brain tumors following contrast-enhanced MR scans in patients without severe renal disease. Further studies are needed to assess the clinical importance of the deposits we observed and to determine whether they are also found in other conditions that alter the integrity of the BBB

  18. Operational experience and validation of the triathlerTM model 425-034(1) single vial liquid scintillation counter for meeting department of energy release criteria

    International Nuclear Information System (INIS)

    Kanady, R. W.

    2008-01-01

    Triathler TM Model 425-034 single vial liquid scintillation counter (LSC) counters have been in use at the Safety and Tritium Applied Research Facility (STAR) for approximately three years. During facility setup and determination of instrumentation needs to support STAR facility operations, the Triathler was chose to assess smearable tritium contamination levels for operational conditions. The Triathler was selected due to the rapid turnaround time for obtaining tritium contamination levels versus other automated batch LSC counters currently in use at the Idaho National Laboratory (INL) and other Dept. of Energy (DOE) installations. Operational experience with the Triathler thus far has shown a high reliability for verifying removable contamination levels at a level of 2 when compared to the Packard TM Tri-Carb 1905 AB/LA Liquid Scintillation Analyzer used by the Reactor Technologies Complex (RTC) Radiochemistry Measurements Laboratory (RML). However, variances in the reported results for activity in DPM/vial from the Triathler versus the Packard Tri-Carb have been noted when operating in the range of 5,000 to 20,000 DPM. These variances make reliability and use of the Triathler suspect for verifying smearable contamination levels meet the release criteria identified in DOE Order 5400.5, Radiation Protection of the Public and Environment. Ensuring that removable tritium contamination levels on materials and equipment intended for free-release to the public are 2 is a requirement in the Idaho National Laboratory (INL) contract. Comprehensive cross-comparisons have been ongoing to ensure the Triathler LSC reported DPM values provide sufficient detection of smearable tritium contamination when cross-compared to other automated liquid scintillation counters available at the INL. (authors)

  19. Spontaneous breaking of supersymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Zumino, B.

    1981-12-01

    There has been recently a revival of interest in supersymmetric gauge theories, stimulated by the hope that supersymmetry might help in clarifying some of the questions which remain unanswered in the so called Grand Unified Theories and in particular the gauge hierarchy problem. In a Grand Unified Theory one has two widely different mass scales: the unification mass M approx. = 10/sup 15/GeV at which the unification group (e.g. SU(5)) breaks down to SU(3) x SU(2) x U(1) and the mass ..mu.. approx. = 100 GeV at which SU(2) x U(1) is broken down to the U(1) of electromagnetism. There is at present no theoretical understanding of the extreme smallness of the ratio ..mu../M of these two numbers. This is the gauge hierarchy problem. This lecture attempts to review the various mechanisms for spontaneous supersymmetry breaking in gauge theories. Most of the discussions are concerned with the tree approximation, but what is presently known about radiative correction is also reviewed.

  20. Spontaneous intracranial hypotension

    International Nuclear Information System (INIS)

    Haritanti, A.; Karacostas, D.; Drevelengas, A.; Kanellopoulos, V.; Paraskevopoulou, E.; Lefkopoulos, A.; Economou, I.; Dimitriadis, A.S.

    2009-01-01

    Spontaneous intracranial hypotension (SIH) is an uncommon but increasingly recognized syndrome. Orthostatic headache with typical findings on magnetic resonance imaging (MRI) are the key to diagnosis. Delayed diagnosis of this condition may subject patients to unnecessary procedures and prolong morbidity. We describe six patients with SIH and outline the important clinical and neuroimaging findings. They were all relatively young, 20-54 years old, with clearly orthostatic headache, minimal neurological signs (only abducent nerve paresis in two) and diffuse pachymeningeal gadolinium enhancement on brain MRI, while two of them presented subdural hygromas. Spinal MRI was helpful in detecting a cervical cerebrospinal fluid leak in three patients and dilatation of the vertebral venous plexus with extradural fluid collection in another. Conservative management resulted in rapid resolution of symptoms in five patients (10 days-3 weeks) and in one who developed cerebral venous sinus thrombosis, the condition resolved in 2 months. However, this rapid clinical improvement was not accompanied by an analogous regression of the brain MR findings that persisted on a longer follow-up. Along with recent literature data, our patients further point out that SIH, to be correctly diagnosed, necessitates increased alertness by the attending physician, in the evaluation of headaches

  1. Spontaneous lateral temporal encephalocele.

    Science.gov (United States)

    Tuncbilek, Gokhan; Calis, Mert; Akalan, Nejat

    2013-01-01

    A spontaneous encephalocele is one that develops either because of embryological maldevelopment or from a poorly understood postnatal process that permits brain herniation to occur. We here report a rare case of lateral temporal encephalocele extending to the infratemporal fossa under the zygomatic arch. At birth, the infant was noted to have a large cystic mass in the right side of the face. After being operated on initially in another center in the newborn period, the patient was referred to our clinic with a diagnosis of temporal encephalocele. He was 6 months old at the time of admission. Computerized tomography scan and magnetic resonance imaging studies revealed a 8 × 9 cm fluid-filled, multiloculated cystic mass at the right infratemporal fossa. No intracranial pathology or connection is seen. The patient was operated on to reduce the distortion effect of the growing mass. The histopathological examination of the sac revealed well-differentiated mature glial tissue stained with glial fibrillary acid protein. This rare clinical presentation of encephaloceles should be taken into consideration during the evaluation of the lateral facial masses in the infancy period, and possible intracranial connection should be ruled out before surgery to avoid complications.

  2. Lack of stimulation of 24-hour growth hormone release by hypocaloric diet in obesity

    DEFF Research Database (Denmark)

    Rasmussen, M H; Juul, A; Kjems, L L

    1995-01-01

    Obesity is associated with a marked reduction in the spontaneous secretion of GH. To investigate the effect of acute alterations in calorie intake on GH release, 24-hr spontaneous GH release was measured during habitual calorie intake as well as during a short term, very low calorie diet (VLCD...

  3. Bilateral spontaneous carotid artery dissection.

    Science.gov (United States)

    Townend, Bradley Scott; Traves, Laura; Crimmins, Denis

    2005-06-01

    Bilateral internal carotid artery dissections have been reported, but spontaneous bilateral dissections are rare. Internal carotid artery dissection can present with a spectrum of symptoms ranging from headache to completed stroke. Two cases of spontaneous bilateral carotid artery dissection are presented, one with headache and minimal symptoms and the other with a stroke syndrome. No cause could be found in either case, making the dissections completely spontaneous. Bilateral internal carotid artery dissection (ICAD) should be considered in young patients with unexplained head and neck pain with or without focal neurological symptoms and signs. The increasing availability of imaging would sustain the higher index of suspicion.

  4. Energy Release in Solar Flares,

    Science.gov (United States)

    1982-10-01

    Plasma Research, Stanford University P. Kaufmanu CRAA/CNPq -Conseiho lacional de Desenvolvimento Cientifico e Tecnologico, Slo Paulo, SP, Brasil D.F...In this case, the two flare filaments drift slowly apart (receding from the magnetic neutral line) so that, late in a flare, regions of the...that the soft X-ray emission was confined to an area small compared to the I alpha flaring region and that the images did not increase in size during

  5. Spontaneous Vesicle Fusion Is Differentially Regulated at Cholinergic and GABAergic Synapses

    Directory of Open Access Journals (Sweden)

    Haowen Liu

    2018-02-01

    Full Text Available The locomotion of C. elegans is balanced by excitatory and inhibitory neurotransmitter release at neuromuscular junctions. However, the molecular mechanisms that maintain the balance of synaptic transmission remain enigmatic. Here, we investigated the function of voltage-gated Ca2+ channels in triggering spontaneous release at cholinergic and GABAergic synapses. Recordings of the miniature excitatory/inhibitory postsynaptic currents (mEPSCs and mIPSCs, respectively showed that UNC-2/CaV2 and EGL-19/CaV1 channels are the two major triggers for spontaneous release. Notably, however, Ca2+-independent spontaneous release was observed at GABAergic but not cholinergic synapses. Functional screening led to the identification of hypomorphic unc-64/Syntaxin-1A and snb-1/VAMP2 mutants in which mEPSCs are severely impaired, whereas mIPSCs remain unaltered, indicating differential regulation of these currents at cholinergic and GABAergic synapses. Moreover, Ca2+-independent spontaneous GABA release was nearly abolished in the hypomorphic unc-64 and snb-1 mutants, suggesting distinct mechanisms for Ca2+-dependent and Ca2+-independent spontaneous release.

  6. Spontaneous intraorbital hematoma: case report

    Directory of Open Access Journals (Sweden)

    Vinodan Paramanathan

    2010-12-01

    Full Text Available Vinodan Paramanathan, Ardalan ZolnourianQueen's Hospital NHS Foundation Trust, Burton on Trent, Staffordshire DE13 0RB, UKAbstract: Spontaneous intraorbital hematoma is an uncommon clinical entity seen in ophthalmology practice. It is poorly represented in the literature. Current evidence attributes it to orbital trauma, neoplasm, vascular malformations, acute sinusitis, and systemic abnormalities. A 65-year-old female presented with spontaneous intraorbital hematoma manifesting as severe ocular pains, eyelid edema, proptosis, and diplopia, without a history of trauma. Computer tomography demonstrated a fairly well defined extraconal lesion with opacification of the paranasal sinuses. The principal differential based on all findings was that of a spreading sinus infection and an extraconal tumor. An unprecedented finding of a spontaneous orbital hematoma was discovered when the patient was taken to theater. We discuss the rarity of this condition and its management.Keywords: hemorrhage, ophthalmology, spontaneous, intra-orbital, hematoma

  7. Spontaneous ischaemic stroke in dogs

    DEFF Research Database (Denmark)

    Gredal, Hanne Birgit; Skerritt, G. C.; Gideon, P.

    2013-01-01

    Translation of experimental stroke research into the clinical setting is often unsuccessful. Novel approaches are therefore desirable. As humans, pet dogs suffer from spontaneous ischaemic stroke and may hence offer new ways of studying genuine stroke injury mechanisms.......Translation of experimental stroke research into the clinical setting is often unsuccessful. Novel approaches are therefore desirable. As humans, pet dogs suffer from spontaneous ischaemic stroke and may hence offer new ways of studying genuine stroke injury mechanisms....

  8. Spontaneity and international marketing performance

    OpenAIRE

    Souchon, Anne L.; Hughes, Paul; Farrell, Andrew M.; Nemkova, Ekaterina; Oliveira, Joao S.

    2016-01-01

    The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. Purpose – The purpose of this paper is to ascertain how today’s international marketers can perform better on the global scene by harnessing spontaneity. Design/methodology/approach – The authors draw on contingency theory to develop a model of the spontaneity – international marketing performance relationship, and identify three potential m...

  9. Computer simulation of the free energy of peptides with the local states method: analogues of gonadotropin releasing hormone in the random coil and stable states.

    Science.gov (United States)

    Meirovitch, H; Koerber, S C; Rivier, J E; Hagler, A T

    1994-07-01

    The Helmholtz free energy F (rather than the energy) is the correct criterion for stability; therefore, calculation of F is important for peptides and proteins that can populate a large number of metastable states. The local states (LS) method proposed by H. Meirovitch [(1977) Chemical Physics Letters, Vol. 45, p. 389] enables one to obtain upper and lower bounds of the conformational free energy, FB (b,l) and FA (b,l), respectively, from molecular dynamics (MD) or Monte Carlo samples. The correlation parameter b is the number of consecutive dihedral or valence angles along the chain that are taken into account explicitly. The continuum angles are approximated by a discretization parameter l; the larger are b and l, the better the approximations; while FA can be estimated efficiently, it is more difficult to estimate FB. The method is further developed here by applying it to MD trajectories of a relatively large molecule (188 atoms), the potent "Asp4-Dpr10" antagonist [cyclo(4/10)-(Ac-delta 3Pro1-D-pFPhe2-D-Trp3-Asp4-Tyr5-D-Nal6-Leu7-Arg8 -Pro9- Dpr10-NH2)] of gonadotropin releasing hormone (GnRH). The molecule was simulated in vacuo at T = 300 K in two conformational states, previously investigated [J. Rizo et al. Journal of the American Chemical Society, (1992) Vol. 114, p. 2860], which differ by the orientation of the N-terminal tail, above (tail up, TU) and below (tail down, TD) the cyclic heptapeptide ring. As in previous applications of the LS method, we have found the following: (1) While FA is a crude approximation for the correct F, results for the difference, delta FA = FA (TD)-FA (TU) converge rapidly to 5.6 (1) kcal/mole as the approximation is improved (i.e., as b and l are increased), which suggests that this is the correct value for delta F; therefore TD is more stable than TU. (The corresponding difference in entropy, T delta SA = 1.3(2) kcal/mole, is equal to the value obtained by the harmonic approximation.) (2) The lowest approximation, which has

  10. Dissipative Continuous Spontaneous Localization (CSL) model.

    Science.gov (United States)

    Smirne, Andrea; Bassi, Angelo

    2015-08-05

    Collapse models explain the absence of quantum superpositions at the macroscopic scale, while giving practically the same predictions as quantum mechanics for microscopic systems. The Continuous Spontaneous Localization (CSL) model is the most refined and studied among collapse models. A well-known problem of this model, and of similar ones, is the steady and unlimited increase of the energy induced by the collapse noise. Here we present the dissipative version of the CSL model, which guarantees a finite energy during the entire system's evolution, thus making a crucial step toward a realistic energy-conserving collapse model. This is achieved by introducing a non-linear stochastic modification of the Schrödinger equation, which represents the action of a dissipative finite-temperature collapse noise. The possibility to introduce dissipation within collapse models in a consistent way will have relevant impact on the experimental investigations of the CSL model, and therefore also on the testability of the quantum superposition principle.

  11. Energy

    International Nuclear Information System (INIS)

    Meister, F.; Ott, F.

    2002-01-01

    This chapter gives an overview of the current energy economy in Austria. The Austrian political aims of sustainable development and climate protection imply a reorientation of the Austrian energy policy as a whole. Energy consumption trends (1993-1998), final energy consumption by energy carrier (indexed data 1993-1999), comparative analysis of useful energy demand (1993 and 1999) and final energy consumption of renewable energy sources by sector (1996-1999) in Austria are given. The necessary measures to be taken in order to reduce the energy demand and increased the use of renewable energy are briefly mentioned. Figs. 5. (nevyjel)

  12. DYSFUNCTIONAL PRESYNAPTIC ALPHA-2-ADRENOCEPTORS EXPOSE FACILITATORY BETA-2-ADRENOCEPTORS IN THE VASCULATURE OF SPONTANEOUSLY HYPERTENSIVE RATS

    NARCIS (Netherlands)

    REMIE, R; VANROSSUM, JXM; COPPES, RP; ZAAGSMA, J

    1992-01-01

    Previous studies on spontaneously hypertensive rats (SHR) have yielded inconsistent information about functional aberrations of the presynaptic alpha(2)- and beta(2)-adrenoceptor-mediated modulation of sympathetic neurotransmitter release. In the present investigation we studied the capacity of

  13. Energy

    International Nuclear Information System (INIS)

    Meister, F.

    2001-01-01

    This chapter of the environmental control report deals with the environmental impact of energy production, energy conversion, atomic energy and renewable energy. The development of the energy consumption in Austria for the years 1993 to 1999 is given for the different energy types. The development of the use of renewable energy sources in Austria is given, different domestic heat-systems are compared, life cycles and environmental balance are outlined. (a.n.)

  14. A case of spontaneous ventriculocisternostomy

    International Nuclear Information System (INIS)

    Yamane, Kanji; Yoshimoto, Hisanori; Harada, Kiyoshi; Uozumi, Tohru; Kuwabara, Satoshi.

    1983-01-01

    The authors experienced a case of spontaneous ventriculocisternostomy diagnosed by CT scan with metrizamide and Conray. Patient was 23-year-old male who had been in good health until one month before admission, when he began to have headache and tinnitus. He noticed bilateral visual acuity was decreased about one week before admission and vomiting appeared two days before admission. He was admitted to our hospital because of bilateral papilledema and remarkable hydrocephalus diagnosed by CT scan. On admission, no abnormal neurological signs except for bilateral papilledema were noted. Immediately, right ventricular drainage was performed. Pressure of the ventricle was over 300mmH 2 O and CSF was clear. PVG and PEG disclosed an another cavity behind the third ventricle, which was communicated with the third ventricle, and occlusion of aqueduct of Sylvius. Metrizamide CT scan and Conray CT scan showed a communication between this cavity and quadrigeminal and supracerebellar cisterns. On these neuroradiological findings, the diagnosis of obstructive hydrocephalus due to benign aqueduct stenosis accompanied with spontaneous ventriculocisternostomy was obtained. Spontaneous ventriculocisternostomy was noticed to produce arrest of hydrocephalus, but with our case, spontaneous regression of such symptoms did not appeared. By surgical ventriculocisternostomy (method by Torkildsen, Dandy, or Scarff), arrest of hydrocephalus was seen in about 50 to 70 per cent, which was the same results as those of spontaneous ventriculocisternostomy. It is concluded that VP shunt or VA shunt is thought to be better treatment of obstructive hydrocephalus than the various kinds of surgical ventriculocisternostomy. (J.P.N.)

  15. Optical antenna enhanced spontaneous emission.

    Science.gov (United States)

    Eggleston, Michael S; Messer, Kevin; Zhang, Liming; Yablonovitch, Eli; Wu, Ming C

    2015-02-10

    Atoms and molecules are too small to act as efficient antennas for their own emission wavelengths. By providing an external optical antenna, the balance can be shifted; spontaneous emission could become faster than stimulated emission, which is handicapped by practically achievable pump intensities. In our experiments, InGaAsP nanorods emitting at ∼ 200 THz optical frequency show a spontaneous emission intensity enhancement of 35 × corresponding to a spontaneous emission rate speedup ∼ 115 ×, for antenna gap spacing, d = 40 nm. Classical antenna theory predicts ∼ 2,500 × spontaneous emission speedup at d ∼ 10 nm, proportional to 1/d(2). Unfortunately, at d antenna efficiency drops below 50%, owing to optical spreading resistance, exacerbated by the anomalous skin effect (electron surface collisions). Quantum dipole oscillations in the emitter excited state produce an optical ac equivalent circuit current, I(o) = qω|x(o)|/d, feeding the antenna-enhanced spontaneous emission, where q|x(o)| is the dipole matrix element. Despite the quantum-mechanical origin of the drive current, antenna theory makes no reference to the Purcell effect nor to local density of states models. Moreover, plasmonic effects are minor at 200 THz, producing only a small shift of antenna resonance frequency.

  16. Spontaneous subcapsular and perirrenal hemorrhage

    International Nuclear Information System (INIS)

    Fuster, M.J.; Saez, J.; Perez-Paya, F.J.; Fernandez, F.

    1997-01-01

    To assess the role of CT in the etiologic diagnosis of spontaneous subcapsular and perirrenal hemorrhage. The CT findings are described in 13 patients presenting subcapsular and perirrenal hemorrhage. Those patients in whom the bleeding was not spontaneous were excluded. Surgical confirmation was obtained in nine cases. In 11 of the 13 cases (84.6%), involving five adenocarcinomas, five angiomyolipoma, two complicated cysts and one case of panarterities nodosa, CT disclosed the underlying pathology. In two cases (15.4%), it only revealed the extension of the hematoma, but gave no clue to its origin. CT is the technique of choice when spontaneous subcapsular and perirrenal hemorrhage is suspected since, in most cases, it reveals the underlying pathology. (Author)

  17. Spontaneous breakdown of PT symmetry in the complex Coulomb ...

    Indian Academy of Sciences (India)

    P T symmetry is spontaneously broken, however, for complex values of the form L = − 1 2 + i . In this case the potential remains P T -symmetric, while the two independent solutions are transformed to each other by the P T operation and at the same time, the two series of discrete energy eigenvalues turn into each ...

  18. Spontaneous isolated celiac artery dissection

    Directory of Open Access Journals (Sweden)

    Tuba Cimilli Ozturk

    2011-01-01

    Full Text Available Dyspepsia with mild, stabbing epigastric discomfort without history of trauma is a very common symptom that emergency physicians see in their daily practice. Vascular emergencies, mostly the aortic dissection and aneurysm, are always described in the differential diagnosis with persistent symptoms. Isolated celiac artery dissection occurring spontaneously is a very rare diagnosis. The involvement of branch vessels is generally observed and patients show various clinical signs and symptoms according to the involved branch vessel. Here we are presenting a case with spontaneous isolated celiac artery dissection, without any branch vessel involvement or visceral damage, detected by computed tomography scans taken on admission.

  19. Spontaneous waves in muscle fibres

    Energy Technology Data Exchange (ETDEWEB)

    Guenther, Stefan; Kruse, Karsten [Department of Theoretical Physics, Saarland University, 66041 Saarbruecken (Germany); Max Planck Institute for the Physics of Complex Systems, Noethnitzer Street 38, 01187 Dresden (Germany)

    2007-11-15

    Mechanical oscillations are important for many cellular processes, e.g. the beating of cilia and flagella or the sensation of sound by hair cells. These dynamic states originate from spontaneous oscillations of molecular motors. A particularly clear example of such oscillations has been observed in muscle fibers under non-physiological conditions. In that case, motor oscillations lead to contraction waves along the fiber. By a macroscopic analysis of muscle fiber dynamics we find that the spontaneous waves involve non-hydrodynamic modes. A simple microscopic model of sarcomere dynamics highlights mechanical aspects of the motor dynamics and fits with the experimental observations.

  20. Cobalt release from inexpensive jewellery

    DEFF Research Database (Denmark)

    Thyssen, Jacob Pontoppidan; Jellesen, Morten Stendahl; Menné, Torkil

    2010-01-01

    . Conclusions: This study showed that only a minority of inexpensive jewellery purchased in Denmark released cobalt when analysed with the cobalt spot test. As fashion trends fluctuate and we found cobalt release from dark appearing jewellery, cobalt release from consumer items should be monitored in the future....... Microstructural characterization was made using scanning electron microscope (SEM) and energy-dispersive spectroscopy (EDS). Results: Cobalt release was found in 4 (1.1%) of 354 items. All these had a dark appearance. SEM/EDS was performed on the four dark appearing items which showed tin-cobalt plating on these...

  1. Energy

    International Nuclear Information System (INIS)

    Bobin, J.L.

    1996-01-01

    Object of sciences and technologies, energy plays a major part in economics and relations between nations. Jean-Louis Bobin, physicist, analyses the relations between man and energy and wonders about fears that delivers nowadays technologies bound to nuclear energy and about the fear of a possible shortage of energy resources. (N.C.). 17 refs., 14 figs., 2 tabs

  2. Human Papillomavirus Infection as a Possible Cause of Spontaneous Abortion and Spontaneous Preterm Delivery

    DEFF Research Database (Denmark)

    Ambühl, Lea Maria Margareta; Baandrup, Ulrik; Dybkær, Karen

    2016-01-01

    , and 10.9% (95% CI; 10.1–11.7) for umbilical cord blood. Summary estimates for HPV prevalence of spontaneous abortions and spontaneous preterm deliveries, in cervix (spontaneous abortions: 24.5%, and pretermdeliveries: 47%, resp.) and placenta (spontaneous abortions: 24.9%, and preterm deliveries: 50......%, resp.), were identified to be higher compared to normal full-term pregnancies (푃 spontaneous abortion, spontaneous preterm...

  3. Energy

    CERN Document Server

    Foland, Andrew Dean

    2007-01-01

    Energy is the central concept of physics. Unable to be created or destroyed but transformable from one form to another, energy ultimately determines what is and isn''t possible in our universe. This book gives readers an appreciation for the limits of energy and the quantities of energy in the world around them. This fascinating book explores the major forms of energy: kinetic, potential, electrical, chemical, thermal, and nuclear.

  4. Spontaneous emission by moving atoms

    International Nuclear Information System (INIS)

    Meystre, P.; Wilkens, M.

    1994-01-01

    It is well known that spontaneous emission is not an intrinsic atomic property, but rather results from the coupling of the atom to the vacuum modes of the electromagnetic field. As such, it can be modified by tailoring the electromagnetic environment into which the atom can radiate. This was already realized by Purcell, who noted that the spontaneous emission rate can be enhanced if the atom placed inside a cavity is resonant with one of the cavity is resonant with one of the cavity modes, and by Kleppner, who discussed the opposite case of inhibited spontaneous emission. It has also been recognized that spontaneous emission need not be an irreversible process. Indeed, a system consisting of a single atom coupled to a single mode of the electromagnetic field undergoes a periodic exchange of excitation between the atom and the field. This periodic exchange remains dominant as long as the strength of the coupling between the atom and a cavity mode is itself dominant. 23 refs., 6 figs

  5. Spontaneous Development of Moral Concepts

    Science.gov (United States)

    Siegal, M.

    1975-01-01

    Moral competence is more difficult to attain than scientific competence. Since language comprehension plays a central role in conceptual development, and moral language is difficult to learn, there is a common deficiency in moral conceptual development. This suggests a theory of non-spontaneous solutions to moral problems. (Author/MS)

  6. Shell theorem for spontaneous emission

    DEFF Research Database (Denmark)

    Kristensen, Philip Trøst; Mortensen, Jakob Egeberg; Lodahl, Peter

    2013-01-01

    and therefore is given exactly by the dipole approximation theory. This surprising result is a spontaneous emission counterpart to the shell theorems of classical mechanics and electrostatics and provides insights into the physics of mesoscopic emitters as well as great simplifications in practical calculations....

  7. Prediction of Spontaneous Preterm Birth

    NARCIS (Netherlands)

    Dijkstra, Karolien

    2002-01-01

    Preterm birth is a leading cause of neonatal morbidity and mortality. It is a major goal in obstetrics to lower the incidence of spontaneous preterm birth (SPB) and related neonatal morbidity and mortality. One of the principal objectives is to discover early markers that would allow us to identify

  8. EAMJ Dec. Spontaneous.indd

    African Journals Online (AJOL)

    2008-12-12

    Dec 12, 2008 ... surgical abortion at one month gestation without any complication. The second pregnancy which was a year prior resulted in a spontaneous miscarriage at two months followed by evacuation of retained products of conception with no post abortion complications. Antibiotics were taken following both.

  9. Spontaneous fission of superheavy nuclei

    Indian Academy of Sciences (India)

    the Yukawa-plus-exponential potential. The microscopic shell and pairing corrections are obtained using the Strutinsky and BCS approaches and the cranking formulae yield the inertia tensor. Finally, the WKB method is used to calculate penetrabilities and spontaneous fission half-lives. Calculations are performed for the ...

  10. Coherent spontaneous radiation from highly bunched electron beams

    International Nuclear Information System (INIS)

    Berryman, K.W.; Crosson, E.R.; Ricci, K.N.

    1995-01-01

    Coherent spontaneous radiation has now been observed in several FELs, and is a subject of great importance to the design of self-amplified spontaneous emission (SASE) devices. We report observations of coherent spontaneous radiation in both FIREFLY and the mid-infrared FEL at the Stanford Picosecond FEL Center. Coherent emission has been observed at wavelengths as short as 5 microns, and enhancement over incoherent levels by as much as a factor of 4x10 4 has been observed at longer wavelengths. The latter behavior was observed at 45 microns in FIREFLY with short bunches produced by off-peak acceleration and dispersive compression. We present temporal measurements of the highly bunched electron distributions responsible for the large enhancements, using both transition radiation and energy-phase techniques

  11. Stereoselectivity of presynaptic autoreceptors modulating dopamine release

    International Nuclear Information System (INIS)

    Arbilla, S.; Langer, S.Z.

    1981-01-01

    The effects of the (R)- and (S)-enantiomers of sulpiride and butaclamol were studied on the spontaneous and field stimulation-evoked release of total radioactivity from slices of rabbit caudate nucleus prelabelled with [ 3 H]dopamine. (S)-Sulpiride in concentrations ranging from 0.01-1μM enhanced the electrically evoked release of [ 3 H]dopamine while (R)-sulpiride was 10 times less potent than (S)-sulpiride. Exposure to (S)-butaclamol (0.1-1 μM) but not to (R)-butaclamol (0.1-10μM) enhanced the field-stimulated release of [ 3 H]dopamine. The facilitatory effects of (S)- and (R)-sulpiride and (S)-butaclamol on the stimulated release of the labelled neurotransmitter were observed under conditions in which these drugs did not modify the spontaneous outflow of radioactivity. Only the active enantiomers of sulpiride and butaclamol antagonized the inhibition by apomorphine (1μM) of the stimulated release of [ 3 H]dopamine. Our results indicate that the presynaptic inhibitory dopamine autoreceptors modulating the stimulation-evoked release of [ 3 H]dopamine in the caudate nucleus are, like the classical postsynaptic dopamine receptors, chemically stereoselective. (Auth.)

  12. Spontaneous Retropharyngeal Emphysema: A Case Report | Chi ...

    African Journals Online (AJOL)

    ... is a rare clinical condition in pediatric otolaryngology. The predominant symptoms are sore throat, odynophagia, dysphagia, and neck pain. Here, we report a case of spontaneous retropharyngeal emphysema. Keywords: Iatrogenic injury, retropharyngeal emphysema, spontaneous retropharyngeal emphysem, trauma ...

  13. La maladie de Grisel : Spontaneous atlantoaxial subluxation

    NARCIS (Netherlands)

    Meek, MF; Robinson, PH; Hermens, RAEC

    Objective: "La maladie de Grisel" (Grisel's syndrome) is a spontaneously occurring atlantoaxial subluxation with torticollis. We present a case of atlantoaxial subluxation occurring in a 20-year period of pharyngoplasty surgery. The occurrence of a "spontaneous" atlantoaxial subluxation after oral

  14. Deep Sludge Gas Release Event Analytical Evaluation

    International Nuclear Information System (INIS)

    Sams, Terry L.

    2013-01-01

    Long Abstract. Full Text. The purpose of the Deep Sludge Gas Release Event Analytical Evaluation (DSGRE-AE) is to evaluate the postulated hypothesis that a hydrogen GRE may occur in Hanford tanks containing waste sludges at levels greater than previously experienced. There is a need to understand gas retention and release hazards in sludge beds which are 200 -300 inches deep. These sludge beds are deeper than historical Hanford sludge waste beds, and are created when waste is retrieved from older single-shell tanks (SST) and transferred to newer double-shell tanks (DST).Retrieval of waste from SSTs reduces the risk to the environment from leakage or potential leakage of waste into the ground from these tanks. However, the possibility of an energetic event (flammable gas accident) in the retrieval receiver DST is worse than slow leakage. Lines of inquiry, therefore, are (1) can sludge waste be stored safely in deep beds; (2) can gas release events (GRE) be prevented by periodically degassing the sludge (e.g., mixer pump); or (3) does the retrieval strategy need to be altered to limit sludge bed height by retrieving into additional DSTs? The scope of this effort is to provide expert advice on whether or not to move forward with the generation of deep beds of sludge through retrieval of C-Farm tanks. Evaluation of possible mitigation methods (e.g., using mixer pumps to release gas, retrieving into an additional DST) are being evaluated by a second team and are not discussed in this report. While available data and engineering judgment indicate that increased gas retention (retained gas fraction) in DST sludge at depths resulting from the completion of SST 241-C Tank Farm retrievals is not expected and, even if gas releases were to occur, they would be small and local, a positive USQ was declared (Occurrence Report EM-RP--WRPS-TANKFARM-2012-0014, 'Potential Exists for a Large Spontaneous Gas Release Event in Deep Settled Waste Sludge'). The purpose of this technical

  15. Generalized Energy-Dependent Q Values for Fission

    Energy Technology Data Exchange (ETDEWEB)

    Vogt, R

    2010-03-31

    We extend Madland's parameterization of the energy release in fission to obtain the dependence of the fission Q value for major and minor actinides on the incident neutron energies in the range 0 {le} E{sub n} {le} 20 MeV. Our parameterization is based on the actinide evaluations recommended for the ENDF/B-VII.1 release. This paper describes the calculation of energydependent fission Q values based on the calculation of the prompt energy release in fission by Madland. This calculation was adopted for use in the LLNL ENDL database and then generalized to obtain the prompt fission energy release for all actinides. Here the calculation is further generalized to the total energy release in fission. There are several stages in a fission event, depending on the time scale. Neutrons and gammas may be emitted at any time during the fission event.While our discussion here is focussed on compound nucleus creation by an incident neutron, similar parameterizations could be obtained for incident gammas or spontaneous fission.

  16. Energy release from pit fires for producing a fire model. Natural-scale analysis of energy release from pit fires for the purpose of establishing a fire model. Final report; Energiefreisetzung von Grubenbraenden zur Erstellung eines Brandmodell. Untersuchung ueber die Energiefreisetzung von Grubenbraenden im natuerlichen Massstab zur Erstellung eines Brandmodells. Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Holke, K.; Michelis, J.

    1996-12-31

    In the context of the research project, measurements were made regarding the energy release in pit fires. The heat flow in fires with standard wood fire objects and in fires on conveyor belts in underground fire sections of the DMT Tremonia experimental pit was measured for this purpose. It was found that the distribution of the mean total heat flow in the roadway crossection depended on the geometric arrangement of the fire object. The belt fire tests carried out have shown that the heat flow depended on the burning behaviour of the belts and with increasing flame propagation on the conveyor belt, the mean heat flow increased. Further, the temperature effects after wood and conveyor belt fires were simulated with the modified `MFIRE` simulation program and were compared with the corresponding experimental results. (orig./MSK) [Deutsch] Im Rahmen des Untersuchungsvorhabens wurden Messungen bezueglich der Energiefreisetzung bei Grubenbraenden durchgefuehrt. Hierzu wurde der Waermefluss bei Braenden mit Standardholzbrandobjekten und bei Foerdergurtbraenden in den untertaegigen Brandstrecken der DMT-Versuchsgrube Tremonia gemessen. Es zeigte sich, dass die Verteilung des mittleren Gesamtwaermeflusses im Streckenquerschnitt von der geometrischen Anordnung des Brandobjektes abhing. Die durchgefuehrten Gurtbrandversuche haben ergeben, dass der Waermefluss vom Brandverhalten der Gurte abhing und mit zunehmender Flammenausbreitung am Foerdergurt der mittlere Waermefluss zunahm. Weiterhin wurden mit dem modifizierten Simulationsprogramm `MFIRE` die Temperaturauswirkungen hinter Holz- und Foerdergurtbraenden simuliert und mit den entsprechenden experimentellen Ergebnissen verglichen. (orig./MSK)

  17. Peripheral administration of palmitoylated prolactin-releasing peptide induces Fos expression in hypothalamic neurons involved in energy homeostasis in NMRI male mice

    Czech Academy of Sciences Publication Activity Database

    Pirník, Zdenko; Železná, Blanka; Kiss, A.; Maletínská, Lenka

    2015-01-01

    Roč. 1625, Nov 2 (2015), s. 151-158 ISSN 0006-8993 R&D Projects: GA ČR(CZ) GA15-08679S Institutional support: RVO:61388963 Keywords : hypothalamus * prolactin-releasing peptide * Fos * oxytocin * hypocretin * mice Subject RIV: CE - Biochemistry Impact factor: 2.561, year: 2015

  18. Energy

    CERN Document Server

    Robertson, William C

    2002-01-01

    Confounded by kinetic energy? Suspect that teaching about simple machines isn t really so simple? Exasperated by electricity? If you fear the study of energy is beyond you, this entertaining book will do more than introduce you to the topic. It will help you actually understand it. At the book s heart are easy-to-grasp explanations of energy basics work, kinetic energy, potential energy, and the transformation of energy and energy as it relates to simple machines, heat energy, temperature, and heat transfer. Irreverent author Bill Robertson suggests activities that bring the basic concepts of energy to life with common household objects. Each chapter ends with a summary and an applications section that uses practical examples such as roller coasters and home heating systems to explain energy transformations and convection cells. The final chapter brings together key concepts in an easy-to-grasp explanation of how electricity is generated. Energy is the second book in the Stop Faking It! series published by NS...

  19. Systematics of spontaneous positron lines

    International Nuclear Information System (INIS)

    Mueller, U.; Reus, T. de; Reinhardt, J.; Mueller, B.; Greiner, W.

    1985-08-01

    Dynamical and spontaneous positron emission are investigated for heavy-ion collisions with long time delay using a semiclassical description. Numerical results and analytical expressions for the characteristic quantities of the resulting spontaneous positron line, i.e., its position, width, and cross section, are compared. The expected behaviour of the line position and cross section and its visibility against the spectrum of dynamically created positrons is discussed in dependence of the united charge Zsub(u) of projectile and target nucleus in a range of systems from Zsub(u)=180 up to Zsub(u)=188. The results are confronted with presently available experimental data, and possible implications on further experiments are worked out. (orig.)

  20. Spontaneous Rotational Inversion in Phycomyces

    KAUST Repository

    Goriely, Alain

    2011-03-01

    The filamentary fungus Phycomyces blakesleeanus undergoes a series of remarkable transitions during aerial growth. During what is known as the stagea IV growth phase, the fungus extends while rotating in a counterclockwise manner when viewed from above (stagea IVa) and then, while continuing to grow, spontaneously reverses to a clockwise rotation (stagea IVb). This phase lasts for 24-48Ah and is sometimes followed by yet another reversal (stageAIVc) before the overall growth ends. Here, we propose a continuum mechanical model of this entire process using nonlinear, anisotropic, elasticity and show how helical anisotropy associated with the cell wall structure can induce spontaneous rotation and, under appropriate circumstances, the observed reversal of rotational handedness. © 2011 American Physical Society.

  1. Spontaneous regression of colon cancer.

    Science.gov (United States)

    Kihara, Kyoichi; Fujita, Shin; Ohshiro, Taihei; Yamamoto, Seiichiro; Sekine, Shigeki

    2015-01-01

    A case of spontaneous regression of transverse colon cancer is reported. A 64-year-old man was diagnosed as having cancer of the transverse colon at a local hospital. Initial and second colonoscopy examinations revealed a typical cancer of the transverse colon, which was diagnosed as moderately differentiated adenocarcinoma. The patient underwent right hemicolectomy 6 weeks after the initial colonoscopy. The resected specimen showed only a scar at the tumor site, and no cancerous tissue was proven histologically. The patient is alive with no evidence of recurrence 1 year after surgery. Although an antitumor immune response is the most likely explanation, the exact nature of the phenomenon was unclear. We describe this rare case and review the literature pertaining to spontaneous regression of colorectal cancer. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. Management of intractable spontaneous epistaxis

    Science.gov (United States)

    Rudmik, Luke

    2012-01-01

    Background: Epistaxis is a common otolaryngology emergency and is often controlled with first-line interventions such as cautery, hemostatic agents, or anterior nasal packing. A subset of patients will continue to bleed and require more aggressive therapy. Methods: Intractable spontaneous epistaxis was traditionally managed with posterior nasal packing and prolonged hospital admission. In an effort to reduce patient morbidity and shorten hospital stay, surgical and endovascular techniques have gained popularity. A literature review was conducted. Results: Transnasal endoscopic sphenopalatine artery ligation and arterial embolization provide excellent control rates but the decision to choose one over the other can be challenging. The role of transnasal endoscopic anterior ethmoid artery ligation is unclear but may be considered in certain cases when bleeding localizes to the ethmoid region. Conclusion: This article will focus on the management of intractable spontaneous epistaxis and discuss the role of endoscopic arterial ligation and embolization as it pertains to this challenging clinical scenario. PMID:22391084

  3. Spontaneous baryogenesis in warm inflation

    OpenAIRE

    Brandenberger, Robert H.; Yamaguchi, Masahide

    2003-01-01

    We discuss spontaneous baryogenesis in the warm inflation scenario. In contrast with standard inflation models, radiation always exists in the warm inflation scenario, and the inflaton must be directly coupled to it. Also, the transition to the post-inflationary radiation dominated phase is smooth and the entropy is not significantly increased at the end of the period of inflation. In addition, after the period of warm inflation ends, the inflaton does not oscillate coherently but slowly roll...

  4. Spontaneous Splenic Rupture in Melanoma

    Directory of Open Access Journals (Sweden)

    Hadi Mirfazaelian

    2014-01-01

    Full Text Available Spontaneous rupture of spleen due to malignant melanoma is a rare situation, with only a few case reports in the literature. This study reports a previously healthy, 30-year-old man who came with chief complaint of acute abdominal pain to emergency room. On physical examination, abdominal tenderness and guarding were detected to be coincident with hypotension. Ultrasonography revealed mild splenomegaly with moderate free fluid in abdominopelvic cavity. Considering acute abdominal pain and hemodynamic instability, he underwent splenectomy with splenic rupture as the source of bleeding. Histologic examination showed diffuse infiltration by tumor. Immunohistochemical study (positive for S100, HMB45, and vimentin and negative for CK, CD10, CK20, CK7, CD30, LCA, EMA, and chromogranin confirmed metastatic malignant melanoma. On further questioning, there was a past history of a nasal dark skin lesion which was removed two years ago with no pathologic examination. Spontaneous (nontraumatic rupture of spleen is an uncommon situation and it happens very rarely due to neoplastic metastasis. Metastasis of malignant melanoma is one of the rare causes of the spontaneous rupture of spleen.

  5. Energies

    International Nuclear Information System (INIS)

    2003-01-01

    In the framework of the National Debate on the energies in a context of a sustainable development some associations for the environment organized a debate on the nuclear interest facing the renewable energies. The first part presents the nuclear energy as a possible solution to fight against the greenhouse effect and the associated problem of the wastes management. The second part gives information on the solar energy and the possibilities of heat and electric power production. A presentation of the FEE (French wind power association) on the situation and the development of the wind power in France, is also provided. (A.L.B.)

  6. Conversion of concentrated solar thermal energy into chemical energy.

    Science.gov (United States)

    Tamaura, Yutaka

    2012-01-01

    When a concentrated solar beam is irradiated to the ceramics such as Ni-ferrite, the high-energy flux in the range of 1500-2500 kW/m(2) is absorbed by an excess Frenkel defect formation. This non-equilibrium state defect is generated not by heating at a low heating-rate (30 K/min), but by irradiating high flux energy of concentrated solar beam rapidly at a high heating rate (200 K/min). The defect can be spontaneously converted to chemical energy of a cation-excess spinel structure (reduced-oxide form) at the temperature around 1773 K. Thus, the O(2) releasing reaction (α-O(2) releasing reaction) proceeds in two-steps; (1) high flux energy of concentrated solar beam absorption by formation of the non-equilibrium Frenkel defect and (2) the O(2) gas formation from the O(2-) in the Frenkel defect even in air atmosphere. The 2nd step proceeds without the solar radiation. We may say that the 1st step is light reaction, and 2nd step, dark reaction, just like in photosynthesis process.

  7. The pathogenesis of radiation leukaemia and its significance for the pathogenesis of spontaneous leukaemias

    International Nuclear Information System (INIS)

    Ludwig, F.C.

    1985-01-01

    There is no radiation leukaemia per se, there is just a spontaneous disposition to this disease owing to irradiation. Weakened immunity is one component of the preleukaemic condition. Changes in organs with tumour-virus-sensitive cells should not be disregarded. Preleukaemic condition involves the release of tumour viruses and the increased occurrence of cells which can react with tumour viruses. (DG) [de

  8. Electrical current nanogeneration driven by spontaneous nanofluidic oscillations.

    Science.gov (United States)

    Gimenez, R; Mercuri, M; Berli, C L A; Bellino, M G

    2018-02-15

    Exploiting natural phenomena is a central route for providing electricity to sustainably drive wearable electronics. Here we report a nano-scale water-driven energy generator that produces tiny electrical currents from spontaneous wetting-drying oscillations in mesoporous thin films. The system was fabricated with a wormlike mesoporous silica film, which was packed in between Cu and silicon contacts. The nanogenerator runs autonomously when a water droplet is laid over the film close to the Cu electrode, as water infiltration into the film under the electrode produces a direct-current. Wetting-drying cycles, which are spontaneously triggered by water evaporation, are perfectly correlated to the generated electrical current. The autonomous water displacement through the film yields a sustained energy conversion until the droplet reservoir vanishes. This novel water-driven nanogenerator opens new alternatives for versatile, mobile and cost-effective self-powering of nanosystems and nanodevices.

  9. Spontaneous oscillations in microfluidic networks

    Science.gov (United States)

    Case, Daniel; Angilella, Jean-Regis; Motter, Adilson

    2017-11-01

    Precisely controlling flows within microfluidic systems is often difficult which typically results in systems being heavily reliant on numerous external pumps and computers. Here, I present a simple microfluidic network that exhibits flow rate switching, bistablity, and spontaneous oscillations controlled by a single pressure. That is, by solely changing the driving pressure, it is possible to switch between an oscillating and steady flow state. Such functionality does not rely on external hardware and may even serve as an on-chip memory or timing mechanism. I use an analytic model and rigorous fluid dynamics simulations to show these results.

  10. General features of spontaneous baryogenesis

    Science.gov (United States)

    Arbuzova, Elena

    2017-04-01

    The classical version of spontaneous baryogenesis is studied in details. It is shown that the relation between the time derivative of the (pseudo)goldstone field and the baryonic chemical potential essentially depends upon the representation chosen for the fermionic fields with non-zero baryonic number (quarks). The kinetic equation, used for the calculations of the cosmological baryon asymmetry, is generalized to the case of non-stationary background. The effects of the finite interval of the integration over time are also included into consideration.

  11. Spontaneous osteonecrosis of the knee

    Energy Technology Data Exchange (ETDEWEB)

    Kattapuram, Taj M. [Department of Radiology, Massachusetts General Hospital (United States); Kattapuram, Susan V. [Department of Radiology, Massachusetts General Hospital (United States)], E-mail: skattapuram@partners.org

    2008-07-15

    Spontaneous osteonecrosis of the knee presents with acute onset of severe, pain in elderly patients, usually female and usually without a history of trauma. Originally described as idiopathic osteonecrosis, the exact etiology is still debated. Evidence suggests that an acute fracture occurs as a result of chronic stress or minor trauma to a weakened subchondral bone plate. The imaging characteristics on MR reflect the age of the lesion and the symptoms. More appropriate terminology may be ' subchondral insufficiency fracture of the knee' or 'focal subchondral osteonecrosis'.

  12. Radiological evaluation of spontaneous pneumoperitoneum

    International Nuclear Information System (INIS)

    Kim, H. S.; Kim, J. D.; Rhee, H. S.

    1982-01-01

    112 cases of spontaneous penumoperitoneum, the causes of which were confirmed by clinical and surgical procedure at Presbyterian Medical Center from January, 1977 to July, 1981 were reviewed radiologically. The results were as follows: 1. Perforation of duodenal ulcer (46/112: 41.1%), stomach ulcer (22/112: 19.6%), and stomach cancer (11/112: 9.8%) were the three most common causes of spontaneous penumoperitoneum. These were 70.5% of all causes. 2. The most common site of free gas was both subdiaphragmatic areas (46: 41.1%). Others were Rt. subdiaphragmatic only (31: 27.7%), both subdiaphragmatic with subhepatic (16: 14.3%), Rt. subdiaphragmatic with subhepatic (7: 6.2%), Rt. subdiaphragmatic only (5: 4.4%), diffuse in abdomen (4: 3.6%), and subhepatic only (3: 2.7%). So 92.0% (103/112) were located in RUQ. 3. The radiological shape of free gas was classified: crescent (52: 46.4%) of small amount; half-moon (21: 18.8%) of moderate amount; large or diffuse (39: 34.8%) of large amount.4. The age between 31 and 60 occupied 69.1% (77/112), and male was predominant (5.2 times). 5. The patient's position showing free air most frequently was erect

  13. A Case of Multiple Spontaneous Keloid Scars

    Directory of Open Access Journals (Sweden)

    Abdulhadi Jfri

    2015-07-01

    Full Text Available Keloid scars result from an abnormal healing response to cutaneous injury or inflammation that extends beyond the borders of the original wound. Spontaneous keloid scars forming in the absence of any previous trauma or surgical procedure are rare. Certain syndromes have been associated with this phenomenon, and few reports have discussed the evidence of single spontaneous keloid scar, which raises the question whether they are really spontaneous. Here, we present a 27-year-old mentally retarded single female with orbital hypertelorism, broad nasal bridge, repaired cleft lip and high-arched palate who presented with progressive multiple spontaneous keloid scars in different parts of her body which were confirmed histologically by the presence of typical keloidal collagen. This report supports the fact that keloid scars can appear spontaneously and are possibly linked to a genetic factor. Furthermore, it describes a new presentation of spontaneous keloid scars in the form of multiple large lesions in different sites of the body.

  14. Spontaneity of communication in individuals with autism.

    Science.gov (United States)

    Chiang, Hsu-Min; Carter, Mark

    2008-04-01

    This article provides an examination of issues related to spontaneity of communication in children with autism. Deficits relating to spontaneity or initiation are frequently reported in individuals with autism, particularly in relation to communication and social behavior. Nevertheless, spontaneity is not necessarily clearly conceptualized or measured. Several approaches to conceptualization of communicative spontaneity are examined with a particular focus on the continuum model and how it might be practically applied. A range of possible explanations for deficits in spontaneity of communication in children with autism is subsequently explored, including external factors (highly structured teaching programs, failure to systematically instruct for spontaneity) and intrinsic characteristics (intellectual disability, stimulus overselectivity, weak central coherence). Possible implications for future research are presented.

  15. Prolonged Paroxysmal Sympathetic Storming Associated with Spontaneous Subarachnoid Hemorrhage

    Directory of Open Access Journals (Sweden)

    Yan Liu

    2013-01-01

    Full Text Available Paroxysmal sympathetic storming (PSS is a rare disorder characterized by acute onset of nonstimulated tachycardia, hypertension, tachypnea, hyperthermia, external posturing, and diaphoresis. It is most frequently associated with severe traumatic brain injuries and has been reported in intracranial tumors, hydrocephalous, severe hypoxic brain injury, and intracerebral hemorrhage. Although excessive release of catecholamine and therefore increased sympathetic activities have been reported in subarachnoid hemorrhage (SAH, there is no descriptive report of PSS primarily caused by spontaneous SAH up to date. Here, we report a case of prolonged PSS in a patient with spontaneous subarachnoid hemorrhage and consequent vasospasm. The sympathetic storming started shortly after patient was rewarmed from hypothermia protocol and symptoms responded to Labetalol, but intermittent recurrence did not resolve until 3 weeks later with treatment involving Midazolam, Fentanyl, Dexmedetomidine, Propofol, Bromocriptine, and minimizing frequency of neurological and vital checks. In conclusion, prolonged sympathetic storming can also be caused by spontaneous SAH. In this case, vasospasm might be a precipitating factor. Paralytics and hypothermia could mask the manifestations of PSS. The treatment of the refractory case will need both timely adjustment of medications and minimization of exogenous stressors or stimuli.

  16. Spontaneous cryptococcal peritonitis in cirrhotic patients.

    Directory of Open Access Journals (Sweden)

    Sungkanuparph S

    2002-07-01

    Full Text Available Spontaneous bacterial peritonitis is a common complication in patients with cirrhosis and ascites. However, spontaneous peritonitis caused by Cryptococcus neoformans is uncommon. Delayed diagnosis of cryptococcal peritonitis often results in death. We describe three cases of spontaneous cryptococcal peritonitis in patients with decompensated cirrhosis. One case had associated symptomatic human immunodeficiency virus infection. Clinical awareness of this entity may lead to the early diagnosis and proper treatment.

  17. Spontaneous Intracranial Hypotension without Orthostatic Headache

    Directory of Open Access Journals (Sweden)

    Tülay Kansu

    2009-03-01

    Full Text Available We report 2 cases of spontaneous intracranial hypotension that presented with unilateral abducens nerve palsy, without orthostatic headache. While sixth nerve palsies improved without any intervention, subdural hematoma was detected with magnetic resonance imaging. We conclude that headache may be absent in spontaneous intracranial hypotension and spontaneous improvement of sixth nerve palsy can occur, even after the development of a subdural hematoma

  18. Spontaneous renal hematoma - a case report

    International Nuclear Information System (INIS)

    Obrzut, M.; Obrzut, M.; Homa, J.; Obrzut, B.

    2006-01-01

    Spontaneous pararenal hematoma is a rare pathology most frequently coexisting with renal tumours, vascular anomalies and inflammatory processes. In some cases one cannot establish its etiology. The paper describes a case of a 58-year-old man with a spontaneous pararenal hematoma and presents a diagnostic algorithm. Ultrasonography and CT play an important role in diagnostics of spontaneous pararenal haemorrhages. These methods enable a precise evaluation of size and location of hematoma and its evolution. (author)

  19. An N-methyl-D-aspartate receptor mediated large, low-frequency, spontaneous excitatory postsynaptic current in neonatal rat spinal dorsal horn neurons.

    Science.gov (United States)

    Thomson, L M; Zeng, J; Terman, G W

    2006-09-01

    Examples of spontaneous oscillating neural activity contributing to both pathological and physiological states are abundant throughout the CNS. Here we report a spontaneous oscillating intermittent synaptic current located in lamina I of the neonatal rat spinal cord dorsal horn. The spontaneous oscillating intermittent synaptic current is characterized by its large amplitude, slow decay time, and low-frequency. We demonstrate that post-synaptic N-methyl-D-aspartate receptors (NMDARs) mediate the spontaneous oscillating intermittent synaptic current, as it is inhibited by magnesium, bath-applied d-2-amino-5-phosphonovalerate (APV), or intracellular MK-801. The NR2B subunit of the NMDAR appears important to this phenomenon, as the NR2B subunit selective NMDAR antagonist, alpha-(4-hydroxphenyl)-beta-methyl-4-benzyl-1-piperidineethanol tartrate (ifenprodil), also partially inhibited the spontaneous oscillating intermittent synaptic current. Inhibition of spontaneous glutamate release by the AMPA/kainate receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) or the mu-opioid receptor agonist [D-Ala2, N-Me-Phe4, Gly5] enkephalin-ol (DAMGO) inhibited the spontaneous oscillating intermittent synaptic current frequency. Marked inhibition of spontaneous oscillating intermittent synaptic current frequency by tetrodotoxin (TTX), but not post-synaptic N-(2,6-dimethylphenylcarbamoylmethyl)triethylammonium bromide (QX-314), suggests that the glutamate release important to the spontaneous oscillating intermittent synaptic current is dependent on active neural processes. Conversely, increasing dorsal horn synaptic glutamate release by GABAA or glycine inhibition increased spontaneous oscillating intermittent synaptic current frequency. Moreover, inhibiting glutamate transporters with threo-beta-benzyloxyaspartic acid (DL-TBOA) increased spontaneous oscillating intermittent synaptic current frequency and decay time. A possible functional role of this spontaneous NMDAR

  20. Biomarkers of spontaneous preterm birth

    DEFF Research Database (Denmark)

    Polettini, Jossimara; Cobo, Teresa; Kacerovsky, Marian

    2017-01-01

    predictors of pregnancy outcome. This systematic review was conducted to synthesize the knowledge on PTB biomarkers identified using multiplex analysis. Three electronic databases (PubMed, EMBASE and Web of Science) were searched for studies in any language reporting the use of multiplex assays for maternal......Despite decades of research on risk indicators of spontaneous preterm birth (PTB), reliable biomarkers are still not available to screen or diagnose high-risk pregnancies. Several biomarkers in maternal and fetal compartments have been mechanistically linked to PTB, but none of them are reliable......) followed by MIP-1β, GM-CSF, Eotaxin, and TNF-RI (two studies) were reported more than once in maternal serum. However, results could not be combined due to heterogeneity in type of sample, study population, assay, and analysis methods. By this systematic review, we conclude that multiplex assays...

  1. Spontaneous Strategies in Innovation Networks

    DEFF Research Database (Denmark)

    Plesner, Ursula; Husted, Emil Krastrup

    and a site ontology, we show how physical sites and objects become constitutive of the inside of virtual worlds through innovation processes. This argument is in line with ANT’s perspective on strategy, where sites and objects are considered a strategically relevant resource in the innovation process...... of materiality in relation to the organization and structuring of virtual worlds. We examine various innovation processes in five Danish entrepreneurial companies where actors continuously struggle to stabilize virtual worlds as platforms for professional communication. With inspiration from actor-network theory....... Empirically, the analysis is founded on descriptive accounts from the five entrepreneurs. By highlighting the spontaneous strategies described by actors, we show how sites and objects are actively used as an element in their strategy, and also how the sites and objects end up facilitating new ways of thinking...

  2. Swarm Intelligence-Inspired Spontaneous Fabrication of Optimal Interconnect at the Micro/Nanoscale.

    Science.gov (United States)

    Su, Meng; Huang, Zhandong; Huang, Yong; Chen, Shuoran; Qian, Xin; Li, Wenbo; Li, Yifan; Pei, Weihua; Chen, Hongda; Li, Fengyu; Song, Yanlin

    2017-02-01

    A spontaneous process is demonstrated to assemble nanoparticles into an optimal interconnect, as natural systems spontaneously figure out the shortest path. The optimal interconnect leads to a 65.9% decrease in electromagnetic interference, a 17.1% decrease in delay, and a 24.5% decrease in energy-delay. It will be of great significance for interconnect fabrication of versatile electronic circuits. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Recurrent spontaneous attacks of dizziness.

    Science.gov (United States)

    Lempert, Thomas

    2012-10-01

    This article describes the common causes of recurrent vertigo and dizziness that can be diagnosed largely on the basis of history. Ninety percent of spontaneous recurrent vertigo and dizziness can be explained by six disorders: (1) Ménière disease is characterized by vertigo attacks, lasting 20 minutes to several hours, with concomitant hearing loss, tinnitus, and aural fullness. Aural symptoms become permanent during the course of the disease. (2) Attacks of vestibular migraine may last anywhere from minutes to days. Most patients have a previous history of migraine headaches, and many experience migraine symptoms during the attack. (3) Vertebrobasilar TIAs affect older adults with vascular risk factors. Most attacks last less than 1 hour and are accompanied by other symptoms from the posterior circulation territory. (4) Vestibular paroxysmia is caused by vascular compression of the eighth cranial nerve. It manifests itself with brief attacks of vertigo that recur many times per day, sometimes with concomitant cochlear symptoms. (5) Orthostatic hypotension causes brief episodes of dizziness lasting seconds to a few minutes after standing up and is relieved by sitting or lying down. In older adults, it may be accompanied by supine hypertension. (6) Panic attacks usually last minutes, occur in specific situations, and are accompanied by choking, palpitations, tremor, heat, and anxiety. Less common causes of spontaneous recurrent vertigo and dizziness include perilymph fistula, superior canal dehiscence, autoimmune inner ear disease, otosclerosis, cardiac arrhythmia, and medication side effects. Neurologists need to venture into otolaryngology, internal medicine, and psychiatry to master the differential diagnosis of recurrent dizziness.

  4. Crows spontaneously exhibit analogical reasoning.

    Science.gov (United States)

    Smirnova, Anna; Zorina, Zoya; Obozova, Tanya; Wasserman, Edward

    2015-01-19

    Analogical reasoning is vital to advanced cognition and behavioral adaptation. Many theorists deem analogical thinking to be uniquely human and to be foundational to categorization, creative problem solving, and scientific discovery. Comparative psychologists have long been interested in the species generality of analogical reasoning, but they initially found it difficult to obtain empirical support for such thinking in nonhuman animals (for pioneering efforts, see [2, 3]). Researchers have since mustered considerable evidence and argument that relational matching-to-sample (RMTS) effectively captures the essence of analogy, in which the relevant logical arguments are presented visually. In RMTS, choice of test pair BB would be correct if the sample pair were AA, whereas choice of test pair EF would be correct if the sample pair were CD. Critically, no items in the correct test pair physically match items in the sample pair, thus demanding that only relational sameness or differentness is available to support accurate choice responding. Initial evidence suggested that only humans and apes can successfully learn RMTS with pairs of sample and test items; however, monkeys have subsequently done so. Here, we report that crows too exhibit relational matching behavior. Even more importantly, crows spontaneously display relational responding without ever having been trained on RMTS; they had only been trained on identity matching-to-sample (IMTS). Such robust and uninstructed relational matching behavior represents the most convincing evidence yet of analogical reasoning in a nonprimate species, as apes alone have spontaneously exhibited RMTS behavior after only IMTS training. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Spontaneous Superlattice Formation in Nanorods through PartialCation Exchange

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, Richard D.; Sadtler, Bryce; Demchenko, Denis O.; Erdonmez, Can K.; Wang, Lin-Wang; Alivisatos, A. Paul

    2007-03-14

    Lattice mismatch strains are widely known to controlnanoscale pattern formation in heteroepitaxy, but such effects have notbeen exploited in colloidal nanocrystal growth. We demonstrate acolloidal route to synthesizing CdS-Ag2S nanorod superlattices throughpartial cation exchange. Strain induces the spontaneous formation ofperiodic structures. Ab initio calculations of the interfacial energy andmodeling of strain energies show that these forces drive theself-organization. The nanorod superlattices exhibit high stabilityagainst ripening and phase mixing. These materials are tunablenear-infrared emitters with potential applications as nanometer-scaleoptoelectronic devices.

  6. Prompt neutron spectrum of the spontaneous fission of californium-252

    International Nuclear Information System (INIS)

    Zamyatnin, Yu.S.; Kroshkin, N.I.; Korostylev, V.A.; Nefedov, V.N.; Ryazanov, D.K.; Starostov, B.I.; Semenov, A.F.

    1976-01-01

    The californium-252 spontaneous fission neutron spectrum was measured in the energy range of 0.01 to 10 MeV by the time-of-flight technique using various neutron detectors. The measurements of 252 Cf neutron spectrum at energies of 0.01 to 5 MeV were performed as a function of fission fragment kinetic energy. The mean neutron spectrum energy in the range of 0.7 to 10 MeV was found from the results of measurements. The irregularity in the 252 Cf neutron spectrum in the neutron energy range of less than 0.7 MeV compared to theoretical values is discussed. The mechanism of 252 Cf neutron emission is also discussed on the basis of neutron yield angle measurements. 12 references

  7. News/Press Releases

    Data.gov (United States)

    Office of Personnel Management — A press release, news release, media release, press statement is written communication directed at members of the news media for the purpose of announcing programs...

  8. A method for the monitoring of metal recrystallization based on the in-situ measurement of the elastic energy release using neutron diffraction

    International Nuclear Information System (INIS)

    Christien, F.; Le Gall, R.; Telling, M. T. F.; Knight, K. S.

    2015-01-01

    A method is proposed for the monitoring of metal recrystallization using neutron diffraction that is based on the measurement of stored energy. Experiments were performed using deformed metal specimens heated in-situ while mounted at the sample position of the High Resolution Powder Diffractometer, HRPD (ISIS Facility), UK. Monitoring the breadth of the resulting Bragg lines during heating not only allows the time-dependence (or temperature-dependence) of the stored energy to be determined but also the recrystallized fraction. The analysis method presented here was developed using pure nickel (Ni270) specimens with different deformation levels from 0.29 to 0.94. In situ temperature ramping as well as isothermal annealing was undertaken. The method developed in this work allows accurate and quantitative monitoring of the recrystallization process. The results from neutron diffraction are satisfactorily compared to data obtained from calorimetry and hardness measurements

  9. A method for the monitoring of metal recrystallization based on the in-situ measurement of the elastic energy release using neutron diffraction.

    Science.gov (United States)

    Christien, F; Telling, M T F; Knight, K S; Le Gall, R

    2015-05-01

    A method is proposed for the monitoring of metal recrystallization using neutron diffraction that is based on the measurement of stored energy. Experiments were performed using deformed metal specimens heated in-situ while mounted at the sample position of the High Resolution Powder Diffractometer, HRPD (ISIS Facility), UK. Monitoring the breadth of the resulting Bragg lines during heating not only allows the time-dependence (or temperature-dependence) of the stored energy to be determined but also the recrystallized fraction. The analysis method presented here was developed using pure nickel (Ni270) specimens with different deformation levels from 0.29 to 0.94. In situ temperature ramping as well as isothermal annealing was undertaken. The method developed in this work allows accurate and quantitative monitoring of the recrystallization process. The results from neutron diffraction are satisfactorily compared to data obtained from calorimetry and hardness measurements.

  10. Stabiliteit spontane taal bij chronische milde afasie

    NARCIS (Netherlands)

    Wolthuis, Nienke; Mendez Orellana, Carolina; Nouwens, Femke; Jonkers, Roel; Visch-Brink, Evy; Bastiaanse, Roelien

    2014-01-01

    In aphasia, an analysis of spontaneous speech provides opportunities to establish the linguistic and communicative abilities, to create suitable therapy plans and to measure language progress. The current study investigated the stability of spontaneous speech within an interview of ten mild aphasic

  11. Spontaneously broken abelian gauge invariant supersymmetric model

    International Nuclear Information System (INIS)

    Mainland, G.B.; Tanaka, K.

    A model is presented that is invariant under an Abelian gauge transformation and a modified supersymmetry transformation. This model is broken spontaneously, and the interplay between symmetry breaking, Goldstone particles, and mass breaking is studied. In the present model, spontaneously breaking the Abelian symmetry of the vacuum restores the invariance of the vacuum under a modified supersymmetry transformation. (U.S.)

  12. Spontaneous Achilles tendon rupture in alkaptonuria | Mohammed ...

    African Journals Online (AJOL)

    Spontaneous Achilles tendon ruptures are uncommon. We present a 46-year-old man with spontaneous Achilles tendon rupture due to ochronosis. To our knowledge, this has not been previously reported in Sudan literature. The tendon of the reported patient healed well after debridement and primary repairs.

  13. Spontaneous rupture of choledochal cyst: case report

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Ho Seob; Nam, Kyung Jin; Lee, Jin Hwa; Kim, Chan Sung; Choi, Jong Cheol; Oh, Jong Young [Dong-a University College of Medicine, Pusan (Korea, Republic of)

    2002-11-01

    Spontaneous rupture of a choledochal cyst leading to biliary peritonitis is a rare complication which can be fatal if not promptly diagnosed. The authors report the ultrasound and CT findings of two cases of spontaneous choledochal cystic rupture and the biliary peritonitis which ensued.

  14. Spontaneity and Equilibrium II: Multireaction Systems

    Science.gov (United States)

    Raff, Lionel M.

    2014-01-01

    The thermodynamic criteria for spontaneity and equilibrium in multireaction systems are developed and discussed. When N reactions are occurring simultaneously, it is shown that G and A will depend upon N independent reaction coordinates, ?a (a = 1,2, ..., N), in addition to T and p for G or T and V for A. The general criteria for spontaneity and…

  15. Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects

    DEFF Research Database (Denmark)

    Rasmussen, M H; Hvidberg, A; Juul, A

    1995-01-01

    using anthropometric measurements and dual energy x-ray absorptiometry scanning (DXA). In the obese subjects, 24-h spontaneous GH release profiles and the GH responses to insulin-induced hypoglycemia and L-arginine as well as basal IGF-I levels and the IGF-I/IGFBP-3 molar ratio were decreased, whereas...... profiles, the decreased GH responses to insulin-induced hypoglycemia and L-arginine, the decreased basal IGF-I levels and IGF-I/IGFBP-3 molar ratio, as well as the elevated insulin levels were returned to normal after a massive weight loss in the obese subjects. In conclusion, the present study has shown...

  16. Early pregnancy angiogenic markers and spontaneous abortion

    DEFF Research Database (Denmark)

    Andersen, Louise B; Dechend, Ralf; Karumanchi, S Ananth

    2016-01-01

    BACKGROUND: Spontaneous abortion is the most commonly observed adverse pregnancy outcome. The angiogenic factors soluble Fms-like kinase 1 and placental growth factor are critical for normal pregnancy and may be associated to spontaneous abortion. OBJECTIVE: We investigated the association between...... maternal serum concentrations of soluble Fms-like kinase 1 and placental growth factor, and subsequent spontaneous abortion. STUDY DESIGN: In the prospective observational Odense Child Cohort, 1676 pregnant women donated serum in early pregnancy, gestational week ..., interquartile range 71-103). Concentrations of soluble Fms-like kinase 1 and placental growth factor were determined with novel automated assays. Spontaneous abortion was defined as complete or incomplete spontaneous abortion, missed abortion, or blighted ovum

  17. Study of spontaneous fission lifetimes using nuclear density functional theory

    Directory of Open Access Journals (Sweden)

    Sadhukhan Jhilam

    2013-12-01

    Full Text Available The spontaneous fission lifetimes have been studied microscopically by minimizing the collective action integral in a two-dimensional collective space of quadrupole moments (Q20, Q22 representing elongation and triaxiality. The microscopic collective potential and inertia tensor are obtained by solving the self-consistent Hartree-Fock-Bogoliubov (HFB equations with the Skyrme energy density functional and mixed pairing interaction. The mass tensor is computed within the perturbative Adiabatic Time-Dependent HFB (ATDHFB approach in the cranking approximation. The dynamic fission trajectories have been obtained by minimizing the collective action using two different numerical techniques. The values of spontaneous fission lifetimes obtained in this way are compared with the static results.

  18. Effects of growth hormone-releasing hormone treatment on milk production and plasma hormones and metabolites in lactating Japanese Black cows under negative energy balance.

    Science.gov (United States)

    Shingu, H; Hodate, K; Kushibiki, S; Touno, E; Oshibe, A; Ueda, Y; Shinoda, M; Ohashi, S

    2009-04-01

    The current study was performed to clarify the effects of GHRH treatment on milk production and plasma hormones and metabolites in lactating Japanese Black cows (a beef breed) under negative energy balance (EB). Ten multiparous lactating beef cows were offered a normal-energy diet daily (110% of ME requirements for maintenance and lactation) until 5 d in milk (DIM) to standardize the cows before dietary treatment. From 6 DIM to the final days (63 DIM) of the experiment, the cows were allotted to experimental dietary treatments: 5 cows were offered a diet formulated for 130% [high-energy diet (HED)] and the remaining 5 cows were offered a diet formulated for 80% [low-energy diet (LED)] of ME requirements for maintenance and lactation. In addition, all cows received daily subcutaneous injections of 3 mg of bovine GHRH from 36 to 56 DIM (GHRH treatment period). Differences in BW of HED- and LED-fed cows at 63 DIM were +28.4 and -7.2 kg compared with BW at 6 DIM, and HED- and LED-fed cows were under positive EB (+23.7 MJ/d) and negative EB (-11.6 MJ/d) throughout the experiment period. Treatment with GHRH increased (P<0.01) the average daily milk yield to 6.2 kg in HED-fed cows compared with a milk yield of 5.3 kg for 7 d before the GHRH treatment period (pretreatment period); LED-fed cows had no increase in milk production from GHRH treatment. Plasma GH, IGF-1, insulin, and glucose concentrations increased (P<0.05) after GHRH treatment in both HED- and LED-fed cows; GHRH treatment also induced an increase (P<0.05) in the net area under the curve of plasma insulin after glucose challenge in both HED- and LED-fed cows. Plasma urea N concentrations were decreased (P<0.05) by GHRH treatment in HED-fed cows, but not in LED-fed cows. Plasma NEFA concentration was unaffected by GHRH treatment in both HED- and LED-fed cows. We conclude that GHRH treatment of lactating Japanese Black cows stimulates endogenous GH and subsequent IGF-1 secretion and might induce an increase in

  19. The (perceived) meaning of spontaneous thoughts.

    Science.gov (United States)

    Morewedge, Carey K; Giblin, Colleen E; Norton, Michael I

    2014-08-01

    Spontaneous thoughts, the output of a broad category of uncontrolled and inaccessible higher order mental processes, arise frequently in everyday life. The seeming randomness by which spontaneous thoughts arise might give people good reason to dismiss them as meaningless. We suggest that it is precisely the lack of control over and access to the processes by which they arise that leads people to perceive spontaneous thoughts as revealing meaningful self-insight. Consequently, spontaneous thoughts potently influence judgment. A series of experiments provides evidence supporting two hypotheses. First, we hypothesize that the more a thought is perceived to be spontaneous, the more it is perceived to provide meaningful self-insight. Participants perceived more spontaneous kinds of thought (e.g., intuition) to reveal greater self-insight than did more controlled kinds of thought in Study 1 (e.g., deliberation). In Studies 2 and 3, participants perceived thoughts with the same content and target to reveal greater self-insight when spontaneously rather than deliberately generated (i.e., childhood memories and impressions formed). Second, we hypothesize that the greater self-insight attributed to thoughts that are (perceived to be) spontaneous leads those thoughts to more potently influence judgment. Participants felt more sexually attracted to an attractive person whom they thought of spontaneously than deliberately in Study 4, and reported their commitment to a current romantic relationship would be more affected by the spontaneous rather than deliberate recollection of a good or bad experience with their romantic partner in Study 5. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  20. Spontaneous fission of superheavy nuclei

    Indian Academy of Sciences (India)

    2015-08-02

    Aug 2, 2015 ... The macroscopic–microscopic method is extended to calculate the deformation energy and penetrability for binary nuclear configurations typical for fission processes. The deformed two-centre shell model is used to obtain single-particle energy levels for the transition region of two partially overlapped ...

  1. Spontaneous Metacognition in Rhesus Monkeys.

    Science.gov (United States)

    Rosati, Alexandra G; Santos, Laurie R

    2016-09-01

    Metacognition is the ability to think about thinking. Although monitoring and controlling one's knowledge is a key feature of human cognition, its evolutionary origins are debated. In the current study, we examined whether rhesus monkeys (Macaca mulatta; N = 120) could make metacognitive inferences in a one-shot decision. Each monkey experienced one of four conditions, observing a human appearing to hide a food reward in an apparatus consisting of either one or two tubes. The monkeys tended to search the correct location when they observed this baiting event, but engaged in information seeking-by peering into a center location where they could check both potential hiding spots-if their view had been occluded and information seeking was possible. The monkeys only occasionally approached the center when information seeking was not possible. These results show that monkeys spontaneously use information about their own knowledge states to solve naturalistic foraging problems, and thus provide the first evidence that nonhumans exhibit information-seeking responses in situations with which they have no prior experience. © The Author(s) 2016.

  2. Spontaneous flocking in human groups.

    Science.gov (United States)

    Belz, Michael; Pyritz, Lennart W; Boos, Margarete

    2013-01-01

    Flocking behaviour, as a type of self-organised collective behaviour, is described as the spatial formation of groups without global control and explicit inter-individual recruitment signals. It can be observed in many animals, such as bird flocks, shoals or herds of ungulates. Spatial attraction between humans as the central component of flocking behaviour has been simulated in a number of seminal models but it has not been detected experimentally in human groups so far. The two other sub-processes of this self-organised collective movement - collision avoidance and alignment - are excluded or held constant respectively in this study. We created a computer-based, multi-agent game where human players, represented as black dots, moved on a virtual playground. The participants were deprived of social cues about each other and could neither communicate verbally nor nonverbally. They played two games: (1) Single Game, where other players were invisible, and (2) Joint Game, where each player could see players' positions in a local radius around himself/herself. We found that individuals approached their neighbours spontaneously if their positions were visible, leading to less spatial dispersion of the whole group compared to moving alone. We conclude that human groups show the basic component of flocking behaviour without being explicitly instructed or rewarded to do so. Copyright © 2012 Elsevier B.V. All rights reserved.

  3. Simultaneous bilateral primary spontaneous pneumothorax

    Directory of Open Access Journals (Sweden)

    Arife Zeybek

    2014-04-01

    Full Text Available Simultaneous bilateral primary pneumothorax is a very rare (1.6 / 100,000 and life-threatening condition. Clinical presentation may vary from mild dyspnea to tension pneumothorax. It may be milder particularly in younger patients, but more severe in patients with advanced age, and tube thoracostomy is a life preserver in the latter group. Since mortality and recurrence rates following tube thoracostomy are high, endoscopic approaches to bilateral hemithorax have been reported in literature. Apical wedge resection and pleural procedures are recommended in video thoracoscopy or mini thoracotomy even if no bulla and/or bleb are detected. Bilateral surgical interventions and additional pleural procedures are associated with increased rate of post-operative complications and longer postoperative hospital-stays. As a first-line approach, the surgical method toward any side of lung with air leakage following a previous tube thoracostomy is considered less invasive, especially in younger patients. Here, we present a case of simultaneous bilateral primary spontaneous pneumothorax (SBPSP in a 21-year old male with no history of smoking and chronic pulmonary disease. A unilateral surgical intervention was performed, and no recurrence was observed during 5-year follow up.

  4. Bilateral spontaneous hemotympanum: Case report

    Directory of Open Access Journals (Sweden)

    Economou Nicolas C

    2006-10-01

    Full Text Available Abstract Background The most common causes of hemotympanum are therapeutic nasal packing, epistaxis, blood disorders and blunt trauma to the head. Hemotympanum is characterized as idiopathic, when it is detected in the presence of chronic otitis media. A rare case of spontaneous bilateral hemotympanum in a patient treated with anticoagulants is presented herein. Case presentation A 72-year-old male presented with acute deterioration of hearing. In the patient's medical history aortic valve replacement 1 year before presentation was reported. Since then he had been administered regularly coumarinic anticoagulants, with INR levels maintained between 3.4 and 4.0. Otoscopy revealed the presence of bilateral hemotympanum. The audiogram showed symmetrical moderately severe mixed hearing loss bilaterally, with the conductive component predominating. Tympanograms were flat bilaterally with absent acoustic reflexes. A computerized tomography scan showed the presence of fluid in the mastoid and middle ear bilaterally. Treatment was conservative and consisted of a 10-day course of antibiotics, anticongestants and temporary interruption of the anticoagulant therapy. After 3 weeks, normal tympanic membranes were found and hearing had returned to previous levels. Conclusion Anticoagulant intake should be included in the differential diagnosis of hemotympanum, because its detection and appropriate treatment may lead to resolution of the disorder.

  5. Potential gas releases from the bottom sludge layer

    International Nuclear Information System (INIS)

    Stewart, C.W.

    1994-04-01

    A layer of sludge about 50 inches deep may exist at the bottom of the tank that has not been mixed by the pump. This bottom sludge layer may be accumulating gas at a rate of 23 SCF/day, resulting in a basal level rise of 0.025 inches/day. At some point sufficient gas may accumulate to release spontaneously. Using reasonable assumptions about gas generation, waste properties and the mechanics of the release process, this may result in gas releases on the order of 1, 000 SCF

  6. Clock frequency estimation under spontaneous emission

    Science.gov (United States)

    Qin, Xi-Zhou; Huang, Jia-Hao; Zhong, Hong-Hua; Lee, Chaohong

    2018-02-01

    We investigate the quantum dynamics of a driven two-level system under spontaneous emission and its application in clock frequency estimation. By using the Lindblad equation to describe the system, we analytically obtain its exact solutions, which show three different regimes: Rabi oscillation, damped oscillation, and overdamped decay. From the analytical solutions, we explore how the spontaneous emission affects the clock frequency estimation. We find that under a moderate spontaneous emission rate, the transition frequency can still be inferred from the Rabi oscillation. Our results enable potential practical applications in frequency measurement and quantum control under decoherence.

  7. Spontaneous Bacterial Peritonitis in Subclinical Hypothyroidism

    Directory of Open Access Journals (Sweden)

    Dalip Gupta

    2013-11-01

    Full Text Available Hypothyroidism is an uncommon cause of ascites. Here we describe a case of a 75 year-old female patient with spontaneous bacterial peritonitis and subclinical hypothyroidism that resolved with thyroid replacement and antibiotic therapy respectively. Ascitic fluid analysis revealed a gram-positive bacterium on gram staining. A review of the literature revealed just one other reported case of myxoedema ascites with concomitant spontaneous bacterial peritonitis and no case has till been reported of spontaneous bacterial peritonitis in subclinical hypothyroidism.

  8. Spontaneous regression of an invasive thymoma.

    Science.gov (United States)

    Yutaka, Yojiro; Omasa, Mitsugu; Shikuma, Kei; Okuda, Masato; Taki, Toshihiko

    2009-05-01

    Although there are many reports of spontaneous regression of noninvasive thymoma, there are no reports of spontaneous regression of an invasive thymoma. Moreover, the mechanism of the spontaneous regression is still unknown. The present case concerns a 47-year-old man who presented with chest pain. Computed tomography (CT) showed a large anterior mediastinal mass with left pleural effusion that occluded the innominate vein. The tissue obtained by video-assisted thoracic surgery suggested a diagnosis of invasive thymic carcinoma. One month later CT showed prominent regression of the tumor, and the tumor was completely resected. On pathology, the diagnosis was thymoma type B3.

  9. Spontaneous Dissection of the Superior Mesenteric Artery

    International Nuclear Information System (INIS)

    Sheldon, Patrick J.; Esther, James B.; Sheldon, Elana L.; Sparks, Steven R.; Brophy, David P.; Oglevie, Steven B.

    2001-01-01

    Spontaneous dissection of the superior mesenteric artery (SMA) is a rare occurrence, especially when not associated with aortic dissection. Currently, only 28 cases appear to have been reported. Due to the scarcity of cases in the literature, the natural history of isolated, spontaneous SMA dissection is unclear. CT has been reported to be useful for the initial diagnosis of SMA dissection [2-5]. We present two recent cases of spontaneous SMA dissection in which enhanced spiral CT was instrumental in following the disease process and guiding clinical decision making

  10. Does Spontaneous Favorability to Power (vs. Universalism) Values Predict Spontaneous Prejudice and Discrimination?

    Science.gov (United States)

    Souchon, Nicolas; Maio, Gregory R; Hanel, Paul H P; Bardin, Brigitte

    2017-10-01

    We conducted five studies testing whether an implicit measure of favorability toward power over universalism values predicts spontaneous prejudice and discrimination. Studies 1 (N = 192) and 2 (N = 86) examined correlations between spontaneous favorability toward power (vs. universalism) values, achievement (vs. benevolence) values, and a spontaneous measure of prejudice toward ethnic minorities. Study 3 (N = 159) tested whether conditioning participants to associate power values with positive adjectives and universalism values with negative adjectives (or inversely) affects spontaneous prejudice. Study 4 (N = 95) tested whether decision bias toward female handball players could be predicted by spontaneous attitude toward power (vs. universalism) values. Study 5 (N = 123) examined correlations between spontaneous attitude toward power (vs. universalism) values, spontaneous importance toward power (vs. universalism) values, and spontaneous prejudice toward Black African people. Spontaneous positivity toward power (vs. universalism) values was associated with spontaneous negativity toward minorities and predicted gender bias in a decision task, whereas the explicit measures did not. These results indicate that the implicit assessment of evaluative responses attached to human values helps to model value-attitude-behavior relations. © 2016 The Authors. Journal of Personality Published by Wiley Periodicals, Inc.

  11. Spontaneous calcium waves in Bergman glia increase with age and hypoxia and may reduce tissue oxygen

    DEFF Research Database (Denmark)

    Mathiesen, Claus; Brazhe, Alexey; Thomsen, Kirsten Joan

    2013-01-01

    loading with OGB-1/AM and SR101. We report that the occurrence of spontaneous waves is 20 times more frequent in the cerebellar cortex of aging as compared with adult mice, which correlated with a reduction in resting brain oxygen tension. In adult mice, spontaneous glial wave activity increased...... on reducing resting brain oxygen tension, and ATP-evoked glial waves reduced the tissue O(2) tension. Finally, although spontaneous Purkinje cell (PC) activity was not associated with increased glia wave activity, spontaneous glial waves did affect intracellular Ca(2+) activity in PCs. The increased wave...... activity during aging, as well as low resting brain oxygen tension, suggests a relationship between glial waves, brain energy homeostasis, and pathology....

  12. Spontaneous emission effects in optically pumped x-ray FEL

    Energy Technology Data Exchange (ETDEWEB)

    Smetanin, I.V.; Grigor`ev, S.V. [P.N. Lebedev Physics Institute, Moscow (Russian Federation)

    1995-12-31

    An effect of spontaneous emission in both quantum and classical regimes of the optically pumped X-ray free electron laser (FEL) in investigated. The quantum properties of an FEL are determined by the ratio of the separation {h_bar} between the absorption and emission lines (i.e. the quanta emitted) and their effective width {Delta}{epsilon} {eta}={h_bar}/{Delta}{epsilon}. In the conventional classical regime {eta} {much_lt} 1 an electron emits and absorbes a great number of shortwavelength photons over the interaction region, the gain in FEL being the result of these competitive processes. In the quantum limit {eta} {much_gt} 1 the emission and absorption lines are completely separated and thus the FEL becomes a two-level quantum oscillator with a completely inverted active medium. Spontaneous emission causes the electron to leave the range of energies where resonant interaction with the laser field occurs, thus effectively reducing the number of particles that take part in generating the induced X-ray signal. This effect is found to be crucial for lasing in optically pumped X-ray FEL. The characteristic relaxation times are calculated for both classical and quantum FEL regimes. It is shown that spontaneous emission results in FEL electron beam threshold current, which is of rather high value. An optimal range of pumping laser intensities is determined.

  13. Ternary fission of spontaneously fissile uranium isomers excited by neutrons

    International Nuclear Information System (INIS)

    Makarenko, V.E.; Molchanov, Y.D.; Otroshchenko, G.A.; Yan'kov, G.B.

    1989-01-01

    Spontaneously fissile isomers (SFI) of uranium were excited in the reactions 236,238 U(n,n') at an average neutron energy 4.5 MeV. A pulsed electrostatic accelerator and time analysis of the fission events were used. Fission fragments were detected by the scintillation method, and long-range particles from fission were detected by an ionization method. The relative probability of fission of nuclei through a spontaneously fissile isomeric state was measured: (1.30±0.01)·10 -4 ( 236 U) and (1.48±0.02)·10 -4 ( 238 U). Half-lives of the isomers were determined: 121±2 nsec (the SFI 236 U) and 267±13 nsec (the SFI 238 U). In study of the ternary fission of spontaneously fissile isotopes of uranium it was established that the probability of the process amounts to one ternary fission per 163±44 binary fissions of the SFI 236 U and one ternary fission per 49±14 binary fissions of the SFI 238 U. The substantial increase of the probability of ternary fission of SFI of uranium in comparison with the case of ternary fission of nuclei which are not in an isomeric state may be related to a special nucleon configuration of the fissile isomers of uranium

  14. Right Diaphragm Spontaneous Rupture: A Surgical Approach

    Directory of Open Access Journals (Sweden)

    Duilio Divisi

    2011-01-01

    Full Text Available We present a case of spontaneous rupture of the diaphragm, characterized by nonspecific symptoms. The rapid diagnosis and appropriate surgical approach led to a positive resolution of the pathology.

  15. Spontaneous cecal perforation secondary to acute fulminant ...

    African Journals Online (AJOL)

    Spontaneous cecal perforation secondary to acute fulminant gastroenteritis: report of a rare case. Duvuru Ram, Vilvapathy S. Karthikeyan, Sarath C. Sistla, Sheik M. Ali, Parnandi Sridhar, Nagarajan Rajkumar ...

  16. Spontaneous Trait Inferences on Social Media.

    Science.gov (United States)

    Levordashka, Ana; Utz, Sonja

    2017-01-01

    The present research investigates whether spontaneous trait inferences occur under conditions characteristic of social media and networking sites: nonextreme, ostensibly self-generated content, simultaneous presentation of multiple cues, and self-paced browsing. We used an established measure of trait inferences (false recognition paradigm) and a direct assessment of impressions. Without being asked to do so, participants spontaneously formed impressions of people whose status updates they saw. Our results suggest that trait inferences occurred from nonextreme self-generated content, which is commonly found in social media updates (Experiment 1) and when nine status updates from different people were presented in parallel (Experiment 2). Although inferences did occur during free browsing, the results suggest that participants did not necessarily associate the traits with the corresponding status update authors (Experiment 3). Overall, the findings suggest that spontaneous trait inferences occur on social media. We discuss implications for online communication and research on spontaneous trait inferences.

  17. Spontane abdominale arteriovenøse fistler

    DEFF Research Database (Denmark)

    Flarup, S; Lindholt, Jes Sanddal

    1997-01-01

    Spontaneous arteriovenous fistulas between major abdominal vessels (AAVF) complicates about 1% of abdominal aortic aneurysms. AAVF produces severe circulatory disturbances with high operative mortality. Preoperative diagnosis is important but difficult due to the varied nature of presentation. Fo...

  18. Depressive disorder and grief following spontaneous abortion.

    Science.gov (United States)

    Kulathilaka, Susil; Hanwella, Raveen; de Silva, Varuni A

    2016-04-12

    Abortion is associated with moderate to high risk of psychological problems such as depression, use of alcohol or marijuana, anxiety, depression and suicidal behaviours. The increased risk of depression after spontaneous abortion in Asian populations has not been clearly established. Only a few studies have explored the relationship between grief and depression after abortion. A study was conducted to assess the prevalence and risk factors of depressive disorder and complicated grief among women 6-10 weeks after spontaneous abortion and compare the risk of depression with pregnant women attending an antenatal clinic. Spontaneous abortion group consisted of women diagnosed with spontaneous abortion by a Consultant Obstetrician. Women with confirmed or suspected induced abortion were excluded. The comparison group consisted of randomly selected pregnant, females attending the antenatal clinics of the two hospitals. Diagnosis of depressive disorder was made according to ICD-10 clinical criteria based on a structured clinical interview. This assessment was conducted in both groups. The severity of depressive symptoms were assessed using the Patients Health Questionnaire (PHQ-9). Grief was assessed using the Perinatal Grief Scale which was administered to the women who had experienced spontaneous abortion. The sample consisted of 137 women in each group. The spontaneous abortion group (mean age 30.39 years (SD = 6.38) were significantly older than the comparison group (mean age 28.79 years (SD = 6.26)). There were more females with ≥10 years of education in the spontaneous abortion group (n = 54; SD = 39.4) compared to the comparison group (n = 37; SD = 27.0). The prevalence of depression in the spontaneous abortion group was 18.6 % (95 CI, 11.51-25.77). The prevalence of depression in the comparison group was 9.5 % (95 CI, 4.52-14.46). Of the 64 women fulfilling criteria for grief, 17 (26.6 %) also fulfilled criteria for a depressive episode. The relative risk of

  19. Postmenopausal spontaneous uterine perforation: Case report

    Science.gov (United States)

    İşlek Seçen, Elçin; Ağış, Hilal; Altunkaya, Canan; Avşar, Ayşe Filiz

    2015-01-01

    Spontaneous uterine rupture and generalized peritonitis caused by pyometra occurs rarely with high morbidity and mortality. A correct and definite diagnosis can be made with laparotomy or laparoscopy. The clinical findings of perforated pyometra are similar to perforation of the gastrointestinal tract and gynecologic symptoms are less frequent, which makes preoperative diagnosis difficult. We report a case of a patient aged 82 years who underwent surgery for spontaneous uterine rupture and generalized peritonitis as a result of pyometra. PMID:28913055

  20. Endometriosis-related spontaneous diaphragmatic rupture.

    Science.gov (United States)

    Triponez, Frédéric; Alifano, Marco; Bobbio, Antonio; Regnard, Jean-François

    2010-10-01

    Non-traumatic, spontaneous diaphragmatic rupture is a rare event whose pathophysiology is not known. We report the case of endometriosis-related spontaneous rupture of the right diaphragm with intrathoracic herniation of the liver, gallbladder and colon. We hypothesize that the invasiveness of endometriotic tissue caused diaphragm fragility, which finally lead to its complete rupture without traumatic event. The treatment consisted of a classical management of diaphragmatic rupture, with excision of the endometriotic nodule followed by medical ovarian suppression for six months.

  1. Spontaneous regression of metastatic Merkel cell carcinoma.

    LENUS (Irish Health Repository)

    Hassan, S J

    2010-01-01

    Merkel cell carcinoma is a rare aggressive neuroendocrine carcinoma of the skin predominantly affecting elderly Caucasians. It has a high rate of local recurrence and regional lymph node metastases. It is associated with a poor prognosis. Complete spontaneous regression of Merkel cell carcinoma has been reported but is a poorly understood phenomenon. Here we present a case of complete spontaneous regression of metastatic Merkel cell carcinoma demonstrating a markedly different pattern of events from those previously published.

  2. Spontaneous intracranial epidural hematoma during rivaroxaban treatment

    Energy Technology Data Exchange (ETDEWEB)

    Ruschel, Leonardo Gilmone; Rego, Felipe Marques Monteiro do; Milano, Jeronimo Buzetti; Jung, Gustavo Simiano; Silva Junior, Luis Fernando; Ramina, Ricardo, E-mail: leonardoruschel@yahoo.com.br [Instituto de Neurologia de Curitiba (INC), Curitiba, PR (Brazil)

    2016-11-15

    According to our research, this is the first case described in the literature of spontaneous intracranial epidural hematoma secondary to the use of Xarelto®. Spontaneous intracranial epidural hematomas are rarely described in the literature. They are associated with infectious diseases of the skull, coagulation disorders, vascular malformations of the dura mater and metastasis to the skull. Long-term post-marketing monitoring and independent reports will probably detect the full spectrum of hemorrhagic complications of the use of rivaroxaban. (author)

  3. Spontaneous intracranial epidural hematoma during rivaroxaban treatment.

    Science.gov (United States)

    Ruschel, Leonardo Gilmone; Rego, Felipe Marques Monteiro do; Milano, Jerônimo Buzetti; Jung, Gustavo Simiano; Silva, Luis Fernando; Ramina, Ricardo

    2016-11-01

    According to our research, this is the first case described in the literature of spontaneous intracranial epidural hematoma secondary to the use of Xareltor. Spontaneous intracranial epidural hematomas are rarely described in the literature. They are associated with infectious diseases of the skull, coagulation disorders, vascular malformations of the dura mater and metastasis to the skull. Long-term post-marketing monitoring and independent reports will probably detect the full spectrum of hemorrhagic complications of the use of rivaroxaban.

  4. Bacterial killing by light-triggered release of silver from biomimetic metal nanorods.

    Science.gov (United States)

    Black, Kvar C L; Sileika, Tadas S; Yi, Ji; Zhang, Ran; Rivera, José G; Messersmith, Phillip B

    2014-01-15

    Illumination of noble metal nanoparticles at the plasmon resonance causes substantial heat generation, and the transient and highly localized temperature increases that result from this energy conversion can be exploited for photothermal therapy by plasmonically heating gold nanorods (NRs) bound to cell surfaces. Here, plasmonic heating is used for the first time to locally release silver from gold core/silver shell (Au@Ag) NRs targeted to bacterial cell walls. A novel biomimetic method of preparing Au@Ag core-shell NRs is employed, involving deposition of a thin organic polydopamine (PD) primer onto Au NR surfaces, followed by spontaneous electroless silver metallization, and conjugation of antibacterial antibodies and passivating polymers for targeting to gram-negative and gram-positive bacteria. Dramatic cytotoxicity of S. epidermidis and E. coli cells targeted with Au@Ag NRs is observed upon exposure to light as a result of the combined antibacterial effects of plasmonic heating and silver release. The antibacterial effect is much greater than with either plasmonic heating or silver alone, implying a strong therapeutic synergy between cell-targeted plasmonic heating and the associated silver release upon irradiation. The findings suggest a potential antibacterial use of Au@Ag NRs when coupled with light irradiation, which has not been previously described. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. FEL gain optimisation and spontaneous radiation

    Energy Technology Data Exchange (ETDEWEB)

    Bali, L.M.; Srivastava, A.; Pandya, T.P. [Lucknow Univ. (India)] [and others

    1995-12-31

    Colson have evaluated FEL gains for small deviations from perfect electron beam injection, with radiation of the same polarisation as that of the wiggler fields. We find that for optimum gain the polarisation of the optical field should be the same as that of the spontaneous emission under these conditions. With a helical wiggler the axial oscillations resulting from small departures from perfect electron beam injection lead to injection dependent unequal amplitudes and phases of the spontaneous radiation in the two transverse directions. Viewed along the axis therefore the spontaneous emission is elliptically polarised. The azimuth of the ellipse varies with the difference of phase of the two transverse components of spontaneous emission but the eccentricity remains the same. With planar wigglers the spontaneous emission viewed in the axial direction is linearly polarised, again with an injection dependent azimuth. For optimum coherent gain of a radiation field its polarisation characteristics must be the same as those of the spontaneous radiation with both types of wiggler. Thus, with a helical wiggler and the data reported earlier, an increase of 10% in the FEL gain at the fundamental frequency and of 11% at the fifth harmonic has been calculated in the small gain per pass limit. Larger enhancements in gain may result from more favourable values of input parameters.

  6. Kinetics of spontaneous baryogenesis in non-stationary background

    Directory of Open Access Journals (Sweden)

    Arbuzova Elena

    2016-01-01

    Full Text Available Generation of the cosmological baryon asymmetry in frameworks of spontaneous baryogenesis is studied in detail. It is shown that the relation between baryonic chemical potential and the time derivative of the (pseudoGoldstone field essentially depends upon the representation chosen for the fermionic fields with non-zero baryonic number (quarks. Kinetic equation is modified and numerically solved in equilibrium for the case of time dependent external background or finite integration time to be applicable to the case when energy conservation law is formally violated.

  7. Langmuir condensation by spontaneous scattering off electrons in two dimensions

    International Nuclear Information System (INIS)

    Ziebell, L F; Yoon, P H; Gaelzer, R; Pavan, J

    2012-01-01

    In a pair of recent papers (Ziebell et al 2008 Phys. Plasmas 15 032303, 2008 Plasma Phys. Control. Fusion 50 085011) it was shown, within the context of weak turbulence theory, that the Langmuir turbulence generated by the bump-in-tail instability does not lead to Langmuir condensation (or accumulation of wave energy and momentum in the long-wavelength regime) in two dimensions. The present analysis finds that it is important to include the spontaneous scattering off Langmuir turbulence of the electrons, which is ignored in the customary literature when compared with a similar process involving ions, in order to recover the condensation of Langmuir waves in two dimensions. (paper)

  8. Intracellular sphingosine releases calcium from lysosomes

    Science.gov (United States)

    Höglinger, Doris; Haberkant, Per; Aguilera-Romero, Auxiliadora; Riezman, Howard; Porter, Forbes D; Platt, Frances M; Galione, Antony; Schultz, Carsten

    2015-01-01

    To elucidate new functions of sphingosine (Sph), we demonstrate that the spontaneous elevation of intracellular Sph levels via caged Sph leads to a significant and transient calcium release from acidic stores that is independent of sphingosine 1-phosphate, extracellular and ER calcium levels. This photo-induced Sph-driven calcium release requires the two-pore channel 1 (TPC1) residing on endosomes and lysosomes. Further, uncaging of Sph leads to the translocation of the autophagy-relevant transcription factor EB (TFEB) to the nucleus specifically after lysosomal calcium release. We confirm that Sph accumulates in late endosomes and lysosomes of cells derived from Niemann-Pick disease type C (NPC) patients and demonstrate a greatly reduced calcium release upon Sph uncaging. We conclude that sphingosine is a positive regulator of calcium release from acidic stores and that understanding the interplay between Sph homeostasis, calcium signaling and autophagy will be crucial in developing new therapies for lipid storage disorders such as NPC. DOI: http://dx.doi.org/10.7554/eLife.10616.001 PMID:26613410

  9. Spontaneous fission of superheavy nuclei

    Indian Academy of Sciences (India)

    collaborators [1,2]. The importance of deformed valleys in the potential energy surfaces. (PES) is that they provide the most favoured fission channels for the decay of superheavy nuclei. For the dynamics study, one has to introduce the influence of mass tensor. We use the results from pairing calculations for the occupation ...

  10. Spontaneous fission of superheavy nuclei

    Indian Academy of Sciences (India)

    2015-08-02

    Aug 2, 2015 ... ... nuclear configurations typical for fission processes. The deformed two-centre shell model is used to obtain single-particle energy levels for the transition region of two partially overlapped daughter and emitted fragment nuclei. The macroscopic part is obtained using the Yukawa-plus-exponential potential.

  11. The correlation between increased reactivity of the bronchi and of mediator releasing cells in asthma

    OpenAIRE

    Neijenst, H.; Degenhart, Herman; Raatgeep, Rolien; Kerrebijn, K.F.

    1980-01-01

    textabstractThe hypothesis that increased reactivity in asthma is not always limited to the bronchi but also exists in the mediator releasing system was investigated in forty‐five asthmatic children, approximately half of whom had exercise‐induced bronchoconstriction (EIB). The bronchial threshold to histamine was measured as an indicator of the reactivity of the bronchi and the histamine release from leucocytes without adding allergen (spontaneous histamine release) was considered as an indi...

  12. Toxics Release Inventory (TRI)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Toxics Release Inventory (TRI) is a dataset compiled by the U.S. Environmental Protection Agency (EPA). It contains information on the release and waste...

  13. Role of membrane cholesterol in spontaneous exocytosis at frog neuromuscular synapses: reactive oxygen species-calcium interplay.

    Science.gov (United States)

    Petrov, Alexey M; Yakovleva, Anastasiya A; Zefirov, Andrey L

    2014-11-15

    Using electrophysiological and optical techniques, we studied the mechanisms by which cholesterol depletion stimulates spontaneous transmitter release by exocytosis at the frog neuromuscular junction. We found that methyl-β-cyclodextrin (MCD, 10 mM)-mediated exhaustion of cholesterol resulted in the enhancement of reactive oxygen species (ROS) production, which was prevented by the antioxidant N-acetyl cysteine (NAC) and the NADPH oxidase inhibitor apocynin. An increase in ROS levels occurred both extra- and intracellularly, and it was associated with lipid peroxidation in synaptic regions. Cholesterol depletion provoked a rise in the intracellular Ca(2+) concentration, which was diminished by NAC and transient receptor potential vanilloid (TRPV) channel blockers (ruthenium red and capsazepine). By contrast, the MCD-induced rise in [Ca(2+)]i remained unaffected if Ca(2+) release from endoplasmic stores was blocked by TMB8 (8-(diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride). The effects of cholesterol depletion on spontaneous release and exocytosis were significantly reduced by the antioxidant, intracellular Ca(2+) chelation with BAPTA-AM and blockers of TRPV channels. Bath application of the calcineurin antagonist cyclosporine A blocked MCD-induced enhancement of spontaneous release/exocytosis, whereas okadaic acid, an inhibitor of phosphatases PP1 and PP2A, had no effect. Thus, our findings indicate that enhancement of spontaneous exocytosis induced by cholesterol depletion may depend on ROS generation, leading to an influx of Ca(2+) via TRPV channels and, subsequently, activation of calcineurin.

  14. Release Data Package for Hanford Site Assessments

    Energy Technology Data Exchange (ETDEWEB)

    Riley, Robert G.; Lopresti, Charles A.; Engel, David W.

    2006-07-01

    Beginning in fiscal year (FY) 2003, the U.S. Department of Energy (DOE) Richland Operations Office initiated activities, including the development of data packages, to support a Hanford assessment. This report describes the data compiled in FY 2003 through 2005 to support the Release Module of the System Assessment Capability (SAC) for the updated composite analysis. This work was completed as part of the Characterization of Systems Project, part of the Remediation and Closure Science Project, the Hanford Assessments Project, and the Characterization of Systems Project managed by Pacific Northwest National Laboratory. Related characterization activities and data packages for the vadose zone and groundwater are being developed under the remediation Decision Support Task of the Groundwater Remediation Project managed by Fluor Hanford, Inc. The Release Module applies release models to waste inventory data from the Inventory Module and accounts for site remediation activities as a function of time. The resulting releases to the vadose zone, expressed as time profiles of annual rates, become source terms for the Vadose Zone Module. Radioactive decay is accounted for in all inputs and outputs of the Release Module. The Release Module is implemented as the VADER (Vadose zone Environmental Release) computer code. Key components of the Release Module are numerical models (i.e., liquid, soil-debris, cement, saltcake, and reactor block) that simulate contaminant release from the different waste source types found at the Hanford Site. The Release Module also handles remediation transfers to onsite and offsite repositories.

  15. Improved calculation of the prompt fission neutron spectrum from the spontaneous fission of /sup 252/Cf: Preliminary results

    International Nuclear Information System (INIS)

    Madland, D.G.

    1988-01-01

    An improved calculation is presented for the prompt fission neutron spectrum N(E) from the spontaneous fission of /sup 252/Cf. In this calculation the fission-spectrum model of Madland and Nix is used, but with several improvements leading to a physically more accurate representation of the spectrum. Specifically, the contributions to N(E) from the entire fission-fragment mass and charge distributions will be calculated instead of calculating on the basis of a seven- point approximation to the peaks of these distributions as has been done in the past. Therefore, values of the energy release in fission, fission-fragment kinetic energy, and compound nucleus cross section for the inverse process will be considered on a point-by-point basis over the fragment yield distributions instead of considering averages of these quantities over the peaks of the distributions. Preliminary results will be presented and compared with a measurement, an earlier calculation, and a recent evaluation of the spectrum. 14 refs., 4 figs

  16. Spontaneous ovulation or male effect in alpacas and llamas

    Directory of Open Access Journals (Sweden)

    Sumar JB

    2016-08-01

    Full Text Available New discoveries in ovulation induced mammals, researchers considered the question of whether spontaneous and induced ovulations are distinct entities or individual parts of a single continuum of a “malefacilitated oestrus and ovulation”. This rigid classification should be taken with precaution, because is possible that the various mechanisms involved in the spontaneous ovulation can, under specific conditions coexist in some determined species. It is possible that male hormones can provoke the ovulation by masculine pheromones. The “Ram Effect” can be used to synchronize ewes naturally, for artificial insemination. Pheromones are specialized hormones released by the ram and smelled by the ewes; they are found in the wool and wax, in such a way that synchronized the heat and the advancement of the breeding season Also, using artificial vaginal-cervical stimulation (AVS with a glass rod, ovulation has been induced in the mink, shrews and felids. This form of tactile stimulation (AVS has found no ability for induction of ovulation in SAC. Additional stimuli/cues are often necessary to facilitate the ovulatory response. They include olfactory, visual, auditory or posture, more of them very common in SAC. Few research studies in alpacas and llamas showed a variable number of females ovulating by the sole proximity of the male to the female, by adopting the copulatory position (posture (sitting or prone position, female to female mounting (tactile, males mounting females covered with aprons to avoid penis intromission (tactile and auditory, interrupted matings, sitting close to a male copulating to a female (visual, olfactory?, the guttural sound (orgling made by the copulating male (auditory, and probably other non-identified cues. The rate of spontaneous ovulation in alpacas and llamas, increase up to 50% during the breeding season. These spontaneous ovulation has been diagnosed by sexual behavior (female rejection to the male, by

  17. Spontaneous body movements in spatial cognition

    Directory of Open Access Journals (Sweden)

    Sergiu eTcaci Popescu

    2012-05-01

    Full Text Available People often perform spontaneous body movements during spatial tasks such as giving complex directions or orienting themselves on maps. How are these spontaneous gestures related to spatial problem-solving? We measured spontaneous movements during a perspective-taking task inspired by map reading. Analyzing the motion data to isolate rotation and translation components of motion in specific geometric relation to the task, we found out that most participants executed spontaneous miniature rotations of the head that were significantly related to the main task parameter. These head rotations were as if participants were trying to align themselves with the orientation on the map either in the image plane or on the ground plane, but with tiny amplitudes, typically below 1% of the actual movements. Our results are consistent with a model of sensorimotor prediction driving spatial reasoning. The efference copy of planned movements triggers this prediction mechanism. The movements themselves may then be mostly inhibited; the small spontaneous gestures that we measure are the visible traces of these planned but inhibited actions.

  18. Bilateral spontaneous rupture of 'hale' kidneys

    International Nuclear Information System (INIS)

    Naumov, N.; Zozikov, B.; Otzetov, A.; Kamenova, M.; Martinova, F.; Kalyonski, R.

    2002-01-01

    A rare case of spontaneous bilateral rupture of the kidneys, occurring consecutively over a one-year period in a young male patient with 'hale' kidneys until then, is described. The patient's past history and thorough examination performed do not justify to assign the case under the heading of some of the etiological factors as the underlying cause of spontaneous kidney rupture. The literature survey on spontaneous bilateral non-tumor ruptures of kidneys shows that over a 20-year period, only 3 cases of bilateral spontaneous ruptures have been reported. It is pointed out that panarteritis nodosa followed by hemorrhagic fever with renal syndrome is the commonest underlying cause of such ruptures. Clinically spontaneous ruptures become manifest with emergency condition presenting severe renal colic, impaired to serious general condition, often with acute abdomen and hemodynamic breakdown, and no past history evidence of renal disease or injury. In the initial phase diagnosing is not always easy; it is usually made on the ground of physical examination and the full range of imaging studies used in urological practice and during operative treatment. Emphasis is laid on the fact that the imaging methods are not invariably sufficient to identify the exact etiological factor giving rise to such a severe condition, but nevertheless these methods have an essential practical bearing on diagnosing a rupture. (authors)

  19. Surgical management of spontaneous hypertensive brainstem hemorrhage

    Directory of Open Access Journals (Sweden)

    Bal Krishna Shrestha

    2015-09-01

    Full Text Available Spontaneous hypertensive brainstem hemorrhage is the spontaneous brainstem hemorrhage associated with long term hypertension but not having definite focal or objective lesion. It is a catastrophic event which has a poor prognosis and usually managed conservatively. It is not uncommon, especially in eastern Asian populations, accounting approximately for 10% of the intracerebral hemorrhage. Before the advent of computed tomography, the diagnosis of brainstem hemorrhage was usually based on the clinical picture or by autopsy and believed to be untreatable via surgery. The introduction of computed tomography permitted to categorize the subtypes of brainstem hemorrhage with more predicted outcome. Continuous ongoing developments in the stereotactic surgery and microsurgery have added more specific surgical management in these patients. However, whether to manage conservatively or promptly with surgical evacuation of hematoma is still a controversy. Studies have shown that an accurate prognostic assessment based on clinical and radiological features on admission is critical for establishing a reasonable therapeutic approach. Some authors have advocate conservative management, whereas others have suggested the efficacy of surgical treatment in brainstem hemorrhage. With the widening knowledge in microsurgical techniques as well as neuroimaging technology, there seems to have more optimistic hope of surgical management of spontaneous hypertensive brainstem hemorrhage for better prognosis. Here we present five cases of severe spontaneous hypertensive brainstem hemorrhage patients who had undergone surgery; and explore the possibilities of surgical management in patients with the spontaneous hypertensive brainstem hemorrhage.

  20. Cursed lamp: the problem of spontaneous abortion.

    Science.gov (United States)

    Simkulet, William

    2017-08-09

    Many people believe human fetuses have the same moral status as adult human persons, that it is wrong to allow harm to befall things with this moral status, and thus voluntary, induced abortion is seriously morally wrong. Recently, many prochoice theorists have argued that this antiabortion stance is inconsistent; approximately 60% of human fetuses die from spontaneous abortion, far more than die from induced abortion, so if antiabortion theorists really believe that human fetuses have significant moral status, they have strong moral obligations to oppose spontaneous abortion. Yet, few antiabortion theorists devote any effort to doing so. Many prochoice theorists argue that to resolve this inconsistency, antiabortion theorists should abandon their opposition to induced abortion. Here, I argue that those who do not abandon their opposition to induced abortion but continue to neglect spontaneous abortion act immorally. Aristotle argues that moral responsibility requires both control and awareness; I argue that once an antiabortion theorist becomes aware of the frequency of spontaneous abortion, they have a strong moral obligation to redirect their efforts towards combating spontaneous abortion; failure to do so is morally monstrous. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  1. Energy Release Through Internal Wave Breaking

    NARCIS (Netherlands)

    van Haren, H.; Gostiaux, L.

    2012-01-01

    The sun inputs huge amounts of heat to the ocean, heat that would stay near the ocean's surface if it were not mechanically mixed into the deep. Warm water is less dense than cold water, so that heated surface waters "float" on top of the cold deep waters. Only active mechanical turbulent mixing can

  2. Flare Ribbon Expansion and Energy Release

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Nobeyama Solar Radio Observatory, Minamisaku, Nagano, 384-1305, Japan. Department of Earth and Planetary Science, University of Tokyo, Hongo, Bunkyo, Tokyo, 113-0033, Japan. Solar-Terrestrial Environment Laboratory, Nagoya University, Toyokawa, Aichi 442-8507, Japan. Kwasan and Hida ...

  3. Sunspot waves and flare energy release

    Czech Academy of Sciences Publication Activity Database

    Sych, R.A.; Karlický, Marian; Altyntsev, A.; Dudík, Jaroslav; Kashapova, L. K.

    2015-01-01

    Roč. 577, May (2015), A43/1-A43/8 ISSN 0004-6361 R&D Projects: GA ČR GAP209/12/0103; GA ČR GAP209/12/1652 Grant - others:EC(XE) 606862 Program:FP7 Institutional support: RVO:67985815 Keywords : Sun flares * Sun oscillations * Sun X-rays Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 4.378, year: 2014

  4. Recycling Frank: Spontaneous emergence of homochirality in noncatalytic systems

    Science.gov (United States)

    Plasson, Raphaël; Bersini, Hugues; Commeyras, Auguste

    2004-01-01

    In this work, we introduce a prebiotically relevant protometabolic pattern corresponding to an engine of deracemization by using an external energy source. The spontaneous formation of a nonracemic mixture of chiral compounds can be observed in out-of-equilibrium systems via a symmetry-breaking phenomenon. This observation is possible thanks to chirally selective autocatalytic reactions (Frank's model) [Frank, F. C. (1953) Biochim. Biophys. Acta 11, 459–463]. We show that the use of a Frank-like model in a recycled system composed of reversible chemical reactions, rather than the classical irreversible system, allows for the emergence of a synergetic autoinduction from simple reactions, without any autocatalytic or even catalytic reaction. This model is described as a theoretical framework, based on the stereoselective reactivity of preexisting chiral monomeric building blocks (polymerization, epimerization, and depolymerization) maintained out of equilibrium by a continuous energy income, via an activation reaction. It permits the self-conversion of all monomeric subunits into a single chiral configuration. Real prebiotic systems of amino acid derivatives can be described on this basis. They are shown to be able to spontaneously reach a stable nonracemic state in a few centuries. In such systems, the presence of epimerization reactions is no more destructive, but in contrast is the central driving force of the unstabilization of the racemic state. PMID:15548617

  5. Spontaneous preterm birth: advances toward the discovery of genetic predisposition.

    Science.gov (United States)

    Strauss, Jerome F; Romero, Roberto; Gomez-Lopez, Nardhy; Haymond-Thornburg, Hannah; Modi, Bhavi P; Teves, Maria E; Pearson, Laurel N; York, Timothy P; Schenkein, Harvey A

    2018-03-01

    innate immune response (eg, CARD6, CARD8, NLRP10, NLRP12, NOD2, TLR10) and antimicrobial peptide/proteins (eg, DEFB1, MBL2). These findings support the concept that preterm labor, at least in part, has an inflammatory etiology, which can be induced by pathogens (ie, intraamniotic infection) or "danger signals" (alarmins) released during cellular stress or necrosis (ie, sterile intraamniotic inflammation). These findings support the notion that preterm birth has a polygenic basis that involves rare mutations or damaging variants in multiple genes involved in innate immunity and host defense mechanisms against microbes and their noxious products. An overlap among the whole exome sequencing-identified genes and other inflammatory conditions associated with preterm birth, such as periodontal disease and inflammatory bowel disease, was observed, which suggests a shared genetic substrate for these conditions. We propose that whole exome sequencing, as well as whole genome sequencing, is the most promising approach for the identification of functionally significant genetic variants responsible for spontaneous preterm birth, at least in the context of pathologic inflammation. The identification of genes that contribute to preterm birth by whole exome sequencing, or whole genome sequencing, promises to yield valuable population-specific biomarkers to identify the risk for spontaneous preterm birth and potential strategies to mitigate such a risk. Published by Elsevier Inc.

  6. Spontaneous Regression of Lumbar Herniated Disc

    Directory of Open Access Journals (Sweden)

    Chun-Wei Chang

    2009-12-01

    Full Text Available Intervertebral disc herniation of the lumbar spine is a common disease presenting with low back pain and involving nerve root radiculopathy. Some neurological symptoms in the majority of patients frequently improve after a period of conservative treatment. This has been regarded as the result of a decrease of pressure exerted from the herniated disc on neighboring neurostructures and a gradual regression of inflammation. Recently, with advances in magnetic resonance imaging, many reports have demonstrated that the herniated disc has the potential for spontaneous regression. Regression coincided with the improvement of associated symptoms. However, the exact regression mechanism remains unclear. Here, we present 2 cases of lumbar intervertebral disc herniation with spontaneous regression. We review the literature and discuss the possible mechanisms, the precipitating factors of spontaneous disc regression and the proper timing of surgical intervention.

  7. Spontaneous hemothorax: primary pleural epithelioid angiosarcoma

    Directory of Open Access Journals (Sweden)

    Amit Panjwani

    2016-01-01

    Full Text Available Spontaneous hemothorax is a rare condition seen in coagulation and vascular disorders. Uncommonly, malignant neoplasms may cause spontaneous hemothorax. Primary pleural epithelioid angiosarcomas (excluding the cases with pleuropulmonary or chest wall involvement are extremely rare pleural tumors, which may be mistaken for mesothelioma or adenocarcinoma, and only 19 cases (one of them from India have been reported in the English literature, to date. It commonly occurs in older men, has a nonspecific clinicoradiological presentation, and carries a poor prognosis with no survivors beyond a year of establishing the diagnosis. We report a case of primary pleural epithelioid angiosarcoma presenting as a life-threatening spontaneous hemothorax. We also present a brief literature review on pleural angiosarcoma.

  8. Computed tomographic findings of spontaneous intracranial hemorrhage

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Seung Sook; Kim, Young Sook; Kim, Young Chul [College of Medicine, Chosun University, Kwangju (Korea, Republic of)

    1987-10-15

    Computed tomography (CT) was a reliable technique to evaluate the exact size and location of spontaneous intracranial hemorrhage and to predict it's prognosis. Fifty-nine cases of spontaneous intracranial hemorrhage were evaluated and reviewed by CT scan. The following results were obtained. 1. The sex ratio of male to female was 1 to 1.4, The highest incidence was in 6th and 7th decades. 2. The most common cause of spontaneous intracranial hemorrhage was hypertension (74.6%), followed by the aneurysm (13.5%), arteriovenous malformation (5.1%), occlusive vascular disease (3.4%), and blood dyscrasia (3.4%). 3. The most common location was basal ganglia and thalamic hemorrhage (37.3%), followed by lobar hemorrhage (27.1%), cerebellar hemorrhage (13.5%), and subarachnoid hemorrhage (11.9%). 4. Primary intraventricular hemorrhage carried the highest mortality. 5. The larger volume of hematoma, the higher the mortality rate.

  9. Spontaneous Perforation of Pyometra: A Case Report

    Directory of Open Access Journals (Sweden)

    2006-01-01

    Full Text Available Pyometra is the accumulation of purulent material in the uterine cavity. Its reported incidence is 0.01–0.5% in gynecologic patients; however, as far as elderly patients are concerned, its incidence is 13.6% [3]. The most common cause of pyometra is malignant diseases of genital tract and the consequences of their treatment (radiotherapy. Other causes are benign tumors like leiomyoma, endometrial polyps, senile cervicitis, cervical occlusion after surgery, puerperal infections, and congenital cervical anomalies. Spontaneous rupture of the uterus is an extremely rare complication of pyometra. To our knowledge, only 21 cases of spontaneous perforation of pyometra have been reported in English literature since 1980. This paper reports an additional case of spontaneous uterine rupture.

  10. Passivation of dental amalgams and mercury release.

    Science.gov (United States)

    Joska, Ludĕk; Marek, Miroslav

    2004-01-01

    In this study the rate of dissolution of mercury from two dental amalgams with different compositions and structures was determined in vitro under different oxidation and abrasion conditions, and the results were correlated with the electrochemical characteristics. A spherical high copper and a lathe-cut very high-copper amalgam were tested in aerated and deaerated artificial saliva. The electrochemical characteristics were determined by potential-time, anodic polarization, polarization resistance and cathodic stripping measurements. Mercury release tests were performed after either stabilization in the solution, or abrasion using SiC papers or rotary toothbrush, with or without toothpaste. Dissolved mercury was determined by atomic absorption spectrophotometry. Both amalgams exhibited passivation, the amalgam with the higher copper content passivating spontaneously even when the oxygen content in the solution was minimized. At a higher oxygen content in the solution the rate of mercury release from the amalgams was lower than when the oxygen content was minimized, and decreased further after a pre-exposure. Brushing generally increased the release. The results show the importance of the oxidation conditions and passivation characteristics of dental amalgams for mercury release, especially in the transient state after abrasion by chewing or tooth brushing.

  11. Spontaneous dispersion of PdO onto acid sites of zeolites studied by in situ DXAFS

    CERN Document Server

    Okumura, K; Niwa, M; Yokota, S; Kato, K; Tanida, H; Uruga, T

    2003-01-01

    The generation of highly dispersed PdO over zeolite supports was studied using in situ energy-dispersive XAFS (DXAFS) technique. From the comparison with the Na-ZSM-5, it was found that the oxidation as well as the spontaneous dispersion of Pd was promoted through the interaction between PdO and acid sites of H-form zeolites. (author)

  12. Crocin loaded nano-emulsions: Factors affecting emulsion properties in spontaneous emulsification.

    Science.gov (United States)

    Mehrnia, Mohammad-Amin; Jafari, Seid-Mahdi; Makhmal-Zadeh, Behzad S; Maghsoudlou, Yahya

    2016-03-01

    Spontaneous emulsification may be used for encapsulating bioactive compounds in food and pharmaceutical industry. It has several advantages over high energy and other low energy methods including, protecting sensitive compounds against severe conditions of high energy method and its ability to minimize surfactant, removal of cosurfactant and thermal stability compared with other low energy methods. In this study, we examined possibility of encapsulating highly soluble crocin in W/O micro-emulsions using spontaneous method which further could be used for making double emulsions. Nonionic surfactants of Span 80 and polyglycerol polyricinoleate (PGPR) were used for making micro-emulsions that showed the high potential of PGPR for spontaneous method. Surfactant to water ratio (SWR%) was evaluated to find the highest amount of aqueous phase which can be dispersed in organic phase. Droplet size decreased by increasing SWR toward the SWR=100% which had the smallest droplet size and then increased at higher levels of surfactant. By increasing SWR, shear viscosity increased which showed the high effect of PGPR on rheological properties. This study shows in addition to W/O micro-emulsions, spontaneous method could be used for preparing stable O/W micro-emulsions. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Ultrashort laser pulse filamentation from spontaneous X-Wave formation in air.

    Science.gov (United States)

    Faccio, Daniele; Averchi, Alessandro; Lotti, Antonio; Di Trapani, Paolo; Couairon, Arnaud; Papazoglou, Dimitris; Tzortzakis, Stelios

    2008-02-04

    The description of ultrashort laser pulse filamentation in condensed media as a spontaneous formation of X waves is shown to apply also to filaments generated in air. Within this framework, a simple explanation is brought for several features of the filament such as the subdiffractive propagation and the energy flux from the weakly localized tails of the X-waves to the intense core.

  14. On spontaneous breakdown in Σ-models

    International Nuclear Information System (INIS)

    Ivanov, E.A.

    1975-01-01

    The group theory aspects of spontaneous breakdown in linear Σ-models are discussed. General conditions are formulated under which multiplet of group G (compact or noncompact) is suitable for constructing the Σ-model with a given subgroup of stability of vacuum. It is shown that the Σ-models of spontaneously broken space-time symmetries can be constructed in general only if some extra coordinates are introduced in addition to an ordinary 4-coordinate xsub(μ). The connection between Σ-models of internal symmetries and appropriate nonlinear realizations has also been investigated

  15. Two cases of spontaneous temporal encephalocele.

    Science.gov (United States)

    Kamiya, Kouhei; Mori, Harushi; Kunimatsu, Akira; Kawai, Kensuke; Usami, Kenichi; Ohtomo, Kuni

    2012-12-01

    This is a report of two cases of spontaneous temporal encephalocele: one was anteroinferior and presented with epilepsy; the other was posteroinferior and presented with facial neuritis and labyrinthitis. Spontaneous temporal encephalocele is relatively rare and apparently not familiar to a majority of primary physicians. It may present with a variety of symptoms according to its anatomical location, including cerebrospinal fluid fistulas, recurrent meningitis, chronic otitis media, hearing loss, facial nerve palsy and medically intractable epilepsy. Attention should be paid to this disease entity, as it is easily overlooked in imaging studies and can leave serious neurological deficits. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  16. Spontaneous abortion and physical strain around implantation

    DEFF Research Database (Denmark)

    Hjollund, N H; Jensen, Tina Kold; Bonde, Jens Peter

    2000-01-01

    Existing studies of physical strain and spontaneous abortion are mainly retrospective or based only on pregnancies that have survived the first trimester. Furthermore, almost all studies have relied on averaged measures of physical strain, which tend to blur an effect if peak values during short...... pregnancy the women recorded physical strain prospectively in a structured diary. Physical strain around the time of implantation was associated with later spontaneous abortion. The adjusted risk ratio for women who reported physical strain higher than average at day 6 to 9 after the estimated date...

  17. Need for spontaneous breakdown of chiral symmetry

    International Nuclear Information System (INIS)

    Salomone, A.; Schechter, J.; Tudron, T.

    1981-01-01

    The question of whether the chiral symmetry of the theory of strong interactions (with massless quarks) is required to be spontaneously broken is examined in the framework of a previously discussed effective Lagrangian for quantum chromodynamics. The assumption that physical masses of the theory be finite leads in a very direct way to the necessity of spontaneous breakdown. This result holds for all N/sub F/> or =2, where N/sub F/ is the number of different flavors of light quarks. The atypical cases N/sub F/ = 1,2 are discussed separately

  18. Spontaneous subdural hematoma associated to Duret hemorrhage

    Directory of Open Access Journals (Sweden)

    William Alves Martins, MD

    2015-03-01

    Full Text Available Subdural hematoma (SH is a neurosurgical emergency, usually caused by head trauma. Non-traumatic causes include aneurysm or arterial–venous malformation rupture, coagulopathy and others. We report the case of a 66 year-old man who developed apparently unprovoked signs of increased intracranial pressure. Brain computed tomography scan showed an acute spontaneous SH, surgically treated. Throughout surgery, a ruptured cortical artery with intensive bleeding appeared and was cauterized. After surgery, patient remained comatose and a new CT demonstrated Duret hemorrhage at the brainstem. Acute spontaneous SH of arterial origin is rare and highly lethal, in which a good prognosis relies on early diagnosis and treatment.

  19. Primer on spontaneous heating and pyrophoricity

    Energy Technology Data Exchange (ETDEWEB)

    1994-12-01

    This primer was prepared as an information resource for personnel responsible for operation of DOE nuclear facilities. It has sections on combustion principles, spontaneous heating/ignition of hydrocarbons and organics, pyrophoric gases and liquids, pyrophoric nonmetallic solids, pyrophoric metals (including Pu and U), and accident case studies. Although the information in this primer is not all-encompassing, it should provide the reader with a fundamental knowledge level sufficient to recognize most spontaneous combustion hazards and how to prevent ignition and widespread fires. This primer is provided as an information resource only, and is not intended to replace any fire protection or hazardous material training.

  20. Cavity enhanced rephased amplified spontaneous emission

    International Nuclear Information System (INIS)

    A Williamson, Lewis; J Longdell, Jevon

    2014-01-01

    Amplified spontaneous emission is usually treated as an incoherent noise process. Recent theoretical and experimental work using rephasing optical pulses has shown that rephased amplified spontaneous emission (RASE) is a potential source of wide bandwidth time-delayed entanglement. Due to poor echo efficiency the plain RASE protocol does not in theory achieve perfect entanglement. Experiments done to date show a very small amount of entanglement at best. Here we show that RASE can, in principle, produce perfect multimode time-delayed two mode squeezing when the active medium is placed inside a Q-switched cavity. (paper)

  1. Spontaneous supersymmetry breaking on the lattice

    Energy Technology Data Exchange (ETDEWEB)

    Wenger, Urs [Albert Einstein Center for Fundamental Physics, Institute for Theoretical Physics, University of Bern, Sidlerstrasse 5, CH-3012 Bern (Switzerland)

    2013-07-01

    We discuss various strategies for regularising supersymmetric quantum field theories on a space-time lattice. In general, simulations of lattice models with spontaneously broken supersymmetry suffer from a fermion sign problem related to the vanishing of the Witten index. We discuss a novel approach which evades this problem in low dimensions by formulating the path integral on the lattice in terms of fermion loops. Then we present exact results on the spectrum and the Witten index for N=2 supersymmetric quantum mechanics and results from simulations of the spontaneously broken N=1 Wess-Zumino model.

  2. Differential angular distribution of prompt gamma rays from spontaneous fission of 252Cf

    Science.gov (United States)

    Skarsvåg, K.

    1980-08-01

    The differential angular distribution of prompt γ rays from spontaneous fission of 252Cf has been measured. The source was on a thick backing, and the measurements have been performed in forward and backward geometries. An NaI(Tl) crystal was used as a γ-ray detector, and the prompt neutrons from fission were rejected by time of flight. The total number of γ rays emitted within 12 ns after fission with energies greater than 0.114 MeV is 9.7 +/- 0.4 per fission, and the total γ-ray energy released is (7.0+/-0.3) MeV per fission. Results from earlier experiments that more γ rays are emitted from the light than from the heavy fragment group, are substantiated. The anisotropy A=I(0°)I(90°)-1 is small and even negative at low energies, reaches a maximum of about 25% at energies of about 0.50-0.65 MeV, and gets gradually smaller at higher energies. No significant difference in the anisotropy as measured with a nonmagnetic (Pt) and a magnetic (Ni) backing has been found. With the assumption that the angular momentum is aligned in a plane perpendicular to the direction of fission, the results can be consistently described within the statistical model in terms of pure dipole and quadrupole radiation with allowance for stretched E2 cascades from even-even fragments. It is concluded that the root mean square value of the primary angular momentum of the fragments is Jrms=(6.5+/-1.0)ℏ, the average angular momentum is decreasing 1.0ℏ per γ ray emitted, and the value of the spin cutoff parameter during γ-ray deexcitation of the fragments is σ=2.4+0.8-0.5. The dipole and the quadrupole components are about equally strong at high γ-ray energies, the dipole component predominates at low energies, and the quadrupole component at intermediate energies. Statistical dipole and quadrupole transitions (stretched for the last ones) account for 38% and 50% of the γ rays, respectively, and stretched E2 transitions in cascades from even-even fragments account for the remaining

  3. Gas retention and release behavior in Hanford single-shell waste tanks

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, C.W.; Brewster, M.E.; Gauglitz, P.A.; Mahoney, L.A.; Meyer, P.A.; Recknagle, K.P.; Reid, H.C.

    1996-12-01

    This report describes the current understanding of flammable gas retention and release in Hanford single-shell waste tanks based on theory, experimental results, and observations of tank behavior. The single-shell tanks likely to pose a flammable gas hazard are listed and described, and photographs of core extrusions and the waste surface are included. The credible mechanisms for significant flammable gas releases are described, and release volumes and rates are quantified as much as possible. The only mechanism demonstrably capable of producing large ({approximately}100 m{sup 3}) spontaneous gas releases is the buoyant displacement, which occurs only in tanks with a relatively deep layer of supernatant liquid. Only the double-shell tanks currently satisfy this condition. All release mechanisms believed plausible in single-shell tanks have been investigated, and none have the potential for large spontaneous gas releases. Only small spontaneous gas releases of several cubic meters are likely by these mechanisms. The reasons several other postulated gas release mechanisms are implausible or incredible are also given.

  4. Gas retention and release behavior in Hanford single-shell waste tanks

    International Nuclear Information System (INIS)

    Stewart, C.W.; Brewster, M.E.; Gauglitz, P.A.; Mahoney, L.A.; Meyer, P.A.; Recknagle, K.P.; Reid, H.C.

    1996-12-01

    This report describes the current understanding of flammable gas retention and release in Hanford single-shell waste tanks based on theory, experimental results, and observations of tank behavior. The single-shell tanks likely to pose a flammable gas hazard are listed and described, and photographs of core extrusions and the waste surface are included. The credible mechanisms for significant flammable gas releases are described, and release volumes and rates are quantified as much as possible. The only mechanism demonstrably capable of producing large (∼100 m 3 ) spontaneous gas releases is the buoyant displacement, which occurs only in tanks with a relatively deep layer of supernatant liquid. Only the double-shell tanks currently satisfy this condition. All release mechanisms believed plausible in single-shell tanks have been investigated, and none have the potential for large spontaneous gas releases. Only small spontaneous gas releases of several cubic meters are likely by these mechanisms. The reasons several other postulated gas release mechanisms are implausible or incredible are also given

  5. A Role for the Inflammasome in Spontaneous Labor at Term with Acute Histologic Chorioamnionitis.

    Science.gov (United States)

    Gomez-Lopez, Nardhy; Romero, Roberto; Xu, Yi; Plazyo, Olesya; Unkel, Ronald; Than, Nandor Gabor; Chaemsaithong, Piya; Chaiworapongsa, Tinnakorn; Dong, Zhong; Tarca, Adi L; Abrahams, Vikki M; Yeo, Lami; Hassan, Sonia S

    2017-06-01

    Inflammasomes are cytosolic signaling platforms that regulate the activation of caspase (CASP)-1, which induces the maturation of interleukin (IL)-1β and IL-18. Herein, we determined whether the chorioamniotic membranes from women in spontaneous labor at term with acute histologic chorioamnionitis express major inflammasome components and whether these changes are associated with the activation of CASP-1 and CASP-4 and the release of mature IL-1β and IL-18. When comparing the chorioamniotic membranes from women in spontaneous labor at term with acute histologic chorioamnionitis to those without this placental lesion, we found that (1) the messenger RNA (mRNA) abundance of NLR family pyrin domain containing 3 ( NLRP3), NLR family CARD domain containing 4 ( NLRC4), absent in melanoma 2 ( AIM2), and nucleotide binding oligomerization domain 2 ( NOD2) was higher; (2) the NLRP3 and NLRC4 protein quantities were increased; (3) the mRNA and protein expressions of CASP-1 and its active forms were greater; (4) CASP-4 was increased at the mRNA level only; (5) the mRNA and protein expressions of IL-1β and its mature form were higher; and (6) a modest increase in the total protein concentration and abundance of the mature form of IL-18 was observed. In vitro incubation of the chorioamniotic membranes with the CASP-1 inhibitor, VX765, decreased the release of endotoxin-induced IL-1β and IL-18 (2-fold) but not IL-6 or tumor necrosis factor α. In conclusion, spontaneous labor at term with acute histologic chorioamnionitis is characterized by an upregulation of inflammasome components which, in turn, may participate in the activation of CASP-1 and lead to the release of mature IL-1β by the chorioamniotic membranes. These results support a role for the inflammasome in the mechanisms responsible for spontaneous labor at term with acute histologic chorioamnionitis.

  6. Fluoroelastomer Fouling Release Coating

    National Research Council Canada - National Science Library

    Malik, Aslam

    1998-01-01

    Our goal is to develop novel fluoroelastomers that exhibit fouling release capabilities and to understand the polymer characteristics that influence the adhesion of biofouling organisms to polymeric substrates...

  7. Compassionate release in California.

    Science.gov (United States)

    Greenspan, J

    1997-01-01

    Several States have instituted compassionate release programs to allow terminally ill inmates to be released early. The programs are politically sensitive, and the California program is highlighted. Early release, called recall of sentence under the State penal code, is a lengthy and cumbersome process that has resulted in early release of nearly 100 prisoners in the past 5 years. Guidelines for community activists who are trying to establish similar programs are provided. The guidelines include contact and discussion with prisoners, outside support through influential organizations, support of State legislators and policy makers, and media involvement in building support for the initiative.

  8. Release the Body, Release the Mind.

    Science.gov (United States)

    Stoner, Martha Goff

    1998-01-01

    A college English teacher describes the anxiety and resentment of students during in-class writing assignments and the successful classroom use of meditation and body movement. Movement seemed to relax the students, change their attitudes, and release their creative impulses to write. Implications related to the body-mind connection are pondered.…

  9. The measurement of prompt neutron spectrum in spontaneous fission of {sup 244}Cm

    Energy Technology Data Exchange (ETDEWEB)

    Batenkov, O.I.; Boykov, G.S.; Drapchinsky, L.V.; Majorov, M.Ju.; Trenkin, V.A. [V.G. Khlopin Radium Inst., Saint Petersburg (Russian Federation)

    1997-03-01

    Under the Program of Measurements of Prompt Fission Neutron Spectra of Minor Actinides for Transmutation Purposes the integral neutron spectrum in spontaneous fission of {sup 244}Cm has been measured by the time-of-flight method in the energy range of 0.1-15 MeV relative to the standard neutron spectrum in {sup 252}Cf spontaneous fission. Essential attention was paid to revealing of possible systematic errors. It is shown, that the {sup 244}Cm spectrum shape may be well described by using Mannhart evaluation with appropriate parameter of Maxwell temperature T{sub M} = 1.37 MeV. (author)

  10. Frictional and elastic energy in gecko adhesive detachment.

    Science.gov (United States)

    Gravish, Nick; Wilkinson, Matt; Autumn, Kellar

    2008-03-06

    Geckos use millions of adhesive setae on their toes to climb vertical surfaces at speeds of over 1 m s(-1). Climbing presents a significant challenge for an adhesive since it requires both strong attachment and easy, rapid removal. Conventional pressure-sensitive adhesives are either strong and difficult to remove (e.g. duct tape) or weak and easy to remove (e.g. sticky notes). We discovered that the energy required to detach adhering tokay gecko setae (W(d)) is modulated by the angle (theta) of a linear path of detachment. Gecko setae resist detachment when dragged towards the animal during detachment (theta = 30 degrees ) requiring W(d) = 5.0+/-0.86(s.e.) J m(-2) to detach, largely due to frictional losses. This external frictional loss is analogous to viscous internal frictional losses during detachment of pressure-sensitive adhesives. We found that, remarkably, setae possess a built-in release mechanism. Setae acted as springs when loaded in tension during attachment and returned elastic energy when detached along the optimal path (theta=130 degrees ), resulting in W(d) = -0.8+/-0.12 J m(-2). The release of elastic energy from the setal shaft probably causes spontaneous release, suggesting that curved shafts may enable easy detachment in natural, and synthetic, gecko adhesives.

  11. Nanoscale Coloristic Pigments: Upper Limits on Releases from Pigmented Plastic during Environmental Aging, In Food Contact, and by Leaching

    DEFF Research Database (Denmark)

    Neubauer, Nicole; Scifo, Lorette; Navratilova, Jana

    2017-01-01

    The life cycle of nanoscale pigments in plastics may cause environmental or human exposure by various release scenarios. We investigated spontaneous and induced release with mechanical stress during/after simulated sunlight and rain degradation of polyethylene (PE) with organic and inorganic pigm...

  12. Wheaten ferments spontaneous fermantation in biotechnological methods

    OpenAIRE

    KAKHRAMON SANOQULOVICH RAKHMONOV; ISABAEV ISMAIL BABADJANOVICH

    2016-01-01

    In article are shown results of research of biotechnological properties of wheaten leavens of spontaneous fermentation (in the example of pea-anisetree leaven) and their analysis. Also is established influence of the given type of leavens on the basic biopolymers of the flour, on the property of the pastry and quality of bread from wheaten flour.

  13. Original article Spontaneous Pregnancy Outcome after Surgical ...

    African Journals Online (AJOL)

    2011-09-28

    Sep 28, 2011 ... Table 2: Spontaneous pregnancy in relation to postoperative semen parameters. (no statistically significant difference), comparable to the mean ages of 22, 28.4 and. 34.9 years, respectively, reported by Bach et al9, Abdel- Meguid et al10 and Baazeem et al11. The mean age of the wives who did or did.

  14. Spontaneous symmetry breakdown in gauge theories

    International Nuclear Information System (INIS)

    Scadron, M.D.

    1982-01-01

    The dynamical theory of spontaneous breakdown correctly predicts the bound states and relates the order parameters of electron-photon superconductivity and quark-gluon chiral symmetry. A similar statement cannot be made for the standard electro-weak gauge symmetry. (author)

  15. Identical Twin Primigravid Sisters -Spontaneous Labour and ...

    African Journals Online (AJOL)

    We report 2 cases of identical twin sisters, the older sibling getting married 14 months earlier but both got pregnant for their first child at about the same time and were managed by the same Obstetrician and fell into spontaneous labour within a few hours of each other. Both were delivered by emergency caesarean section ...

  16. SPONTANEOUS CP VIOLATION AND QUARK MASS AMBIGUITIES.

    Energy Technology Data Exchange (ETDEWEB)

    CREUTZ,M.

    2004-09-21

    I explore the regions of quark masses where CP will be spontaneously broken in the strong interactions. The boundaries of these regions are controlled by the chiral anomaly, which manifests itself in ambiguities in the definition of non-degenerate quark masses. In particular, the concept of a single massless quark is ill defined.

  17. 1 INFLUENCE OF SPONTANEOUS FERMENTATION ON SOME ...

    African Journals Online (AJOL)

    RopSvr

    Spontaneous fermentation has been identified to improve the quality characteristics of foods derived from them. When combined with cowpea fortification and nixtamalization, it is expected to improve the nutritional, functional, physico-chemical and sensory qualities of maize based foods thereby improving the qualities as ...

  18. Association between Nutritional Status with Spontaneous Abortion

    Directory of Open Access Journals (Sweden)

    Rahimeh Ahmadi

    2016-11-01

    Full Text Available Background: Spontaneous abortion is the most common adverse pregnancy outcome. We aimed to investigate a possible link between nutrient deficiencies and the risk of spontaneous abortion. Materials and Methods: This case-control study included the case group (n=331 experiencing a spontaneous abortion before 14 weeks of pregnancy and the control group (n=331 who were healthy pregnant women over 14 weeks of pregnancy. The participants filled out Food Frequency Questionnaire (FFQ, in which they reported their frequency of consumption for a given serving of each food item during the past three months, on a daily, weekly or monthly basis. The reported frequency for each food item was converted to a daily intake. Then, consumption of nutrients was compared between the two groups. Results: There are significant differences between the two groups regarding consumed servings/day of vegetables, bread and cereal, meat, poultry, fish, eggs, beans, fats, oils and dairy products (P=0.012, P<0.001, P=0.004, P<0.001, P=0.019, respectively. There are significant differences between the two groups in all micronutrient including folic acid, iron, vitamin C, vitamin B6, vitamin B12 and zinc (P<0.001. Conclusion: Poor nutrientions may be correlated with increased risk of spontaneous abortion

  19. Spontaneous regression of an intraspinal disc cyst

    Energy Technology Data Exchange (ETDEWEB)

    Demaerel, P.; Eerens, I.; Wilms, G. [University Hospital, Leuven (Belgium). Dept. of Radiology; Goffin, J. [Dept. of Neurosurgery, University Hospitals, Leuven (Belgium)

    2001-11-01

    We present a patient with a so-called disc cyst. Its location in the ventrolateral epidural space and its communication with the herniated disc are clearly shown. The disc cyst developed rapidly and regressed spontaneously. This observation, which has not been reported until now, appears to support focal degeneration with cyst formation as the pathogenesis. (orig.)

  20. Spontaneous rupture of an infected renal cyst

    Energy Technology Data Exchange (ETDEWEB)

    Kopp, W.; Toelly, E.; Ebner, F.; Kullnig, P.

    1986-07-01

    Spontaneous or traumatic rupture of renal cysts is a rare occurrence. The contents of the cyst can perforate into the renal calyx system or into the perirenal space. Perforation into the peritoneal cavity has also been described (1, 2, 4, 5).

  1. Proteomic Biomarkers for Spontaneous Preterm Birth

    DEFF Research Database (Denmark)

    Kacerovsky, Marian; Lenco, Juraj; Musilova, Ivana

    2014-01-01

    This review aimed to identify, synthesize, and analyze the findings of studies on proteomic biomarkers for spontaneous preterm birth (PTB). Three electronic databases (Medline, Embase, and Scopus) were searched for studies in any language reporting the use of proteomic biomarkers for PTB published...

  2. Spontaneous emission from saturated parametric amplifiers

    DEFF Research Database (Denmark)

    Rottwitt, Karsten; Ott, Johan Raunkjær; Steffensen, Henrik

    2009-01-01

    Noise performance of parametric amplifiers is typically calculated assuming un-depleted operation. However, in many applications especially when applied as regenerative amplifiers in systems based on phase shift keyed modulation schemes, this assumption is not valid. Here we show the impact...... on accumulated spontaneous emission for a parametric amplifier operated in saturation....

  3. Spontaneous Non-verbal Counting in Toddlers

    Science.gov (United States)

    Sella, Francesco; Berteletti, Ilaria; Lucangeli, Daniela; Zorzi, Marco

    2016-01-01

    A wealth of studies have investigated numerical abilities in infants and in children aged 3 or above, but research on pre-counting toddlers is sparse. Here we devised a novel version of an imitation task that was previously used to assess spontaneous focusing on numerosity (i.e. the predisposition to grasp numerical properties of the environment)…

  4. Editorial: Spontaneous bacterial peritonitis | Lule | East African ...

    African Journals Online (AJOL)

    Journal Home > Vol 81, No 3 (2004) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Editorial: Spontaneous bacterial peritonitis. GN Lule. Abstract. No Abstract Available. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT ...

  5. Spontaneous conversion of first onset atrial fibrillation

    DEFF Research Database (Denmark)

    Lindberg, Søren Østergaard; Hansen, Sidsel; Nielsen, Tonny

    2011-01-01

    Background  We studied all patients admitted to hospital with first onset atrial fibrillation (AF) to determine the probability of spontaneous conversion to sinus rhythm and to identify factors predictive of such a conversion. Methods and Results  We retrospectively reviewed charts of 438...

  6. Spontaneous dimensional reduction in quantum gravity

    Science.gov (United States)

    Carlip, S.

    2016-07-01

    Hints from a number of different approaches to quantum gravity point to a phenomenon of “spontaneous dimensional reduction” to two spacetime dimensions near the Planck scale. I examine the physical meaning of the term “dimension” in this context, summarize the evidence for dimensional reduction, and discuss possible physical explanations.

  7. Surgical management of spontaneous ruptured hepatocellular adenoma

    Directory of Open Access Journals (Sweden)

    Marcelo Augusto Fontenelle Ribeiro Junior

    2009-01-01

    Full Text Available AIMS: Spontaneous ruptured hepatocellular adenoma (SRHA is a rare life-threatening condition that may require surgical treatment to control hemorrhaging and also stabilize the patient. We report a series of emergency surgeries performed at our institution for this condition. METHODS: We reviewed medical records and radiology files of 28 patients (from 1989 to 2006 with a proven diagnosis of hepatocellular adenoma (HA. Three (10.7% of 28 patients had spontaneous ruptured hepatocellular adenoma, two of which were associated with intrahepatic hemorrhage while one had intraperitoneal bleeding. Two patients were female and one was male. Both female patients had a background history of oral contraceptive use. Sudden abdominal pain associated with hemodynamic instability occurred in all patients who suffered from spontaneous ruptured hepatocellular adenoma. The mean age was 41.6 years old. The preoperative assessment included liver function tests, ultrasonography and computed tomography. RESULTS: The surgical approaches were as follows: right hemihepatectomy for controlling intraperitoneal bleeding, and right extended hepatectomy and non-anatomic resection of the liver for intrahepatic hemorrhage. There were no deaths, and the postoperative complications were bile leakage and wound infection (re-operation, as well as intraperitoneal abscess (re-operation and pleural effusion. CONCLUSION: Spontaneous ruptured hepatocellular adenoma may be treated by surgery for controlling hemorrhages and stabilizing the patient, and the decision to operate depends upon both the patient's condition and the expertise of the surgical team.

  8. Chronic Allium sativum administration alters spontaneous ...

    African Journals Online (AJOL)

    This study was conducted to investigate the effects of Allium sativum extract on the medial prefrontal cortex and neurobehaviour of adult Wistar rats. ... altered spontaneous alternation, while cellular pathologic changes were observed in the medial prefrontal cortex of these test groups in a dose dependent sequence.

  9. Spontaneous hedonic reactions to social media cues

    NARCIS (Netherlands)

    Koningsbruggen, G.M. van; Hartmann, T.; Eden, A.; Veling, H.P.

    2017-01-01

    Why is it so difficult to resist the desire to use social media? One possibility is that frequent social media users possess strong and spontaneous hedonic reactions to social media cues, which, in turn, makes it difficult to resist social media temptations. In two studies (total N = 200), we

  10. Recurrent spontaneous intracerebral hemorrhage associated with ...

    African Journals Online (AJOL)

    Spontaneous intracerebral hemorrhage (ICH) accounts for 15% of stroke cases in the US and Europe and up to 30% in Asian populations. Intracerebral hemorrhage is a relatively uncommon form of stroke-it causes only 10 to 15 percent of all strokes. It is more disabling and has a higher mortality rate than ischemic stroke, ...

  11. Ovarian hyperstimulation syndrome in a spontaneous pregnancy ...

    African Journals Online (AJOL)

    It is known that most cases of Ovarian Hyperstimulation Syndrome (OHSS) are associated with the therapies for ovulation induction. However, OHSS may rarely be associated with a spontaneous ovulatory cycle, usually in the case of multiple gestations, hypothyroidism or polycystic ovary syndrome. We report a case of ...

  12. Spontaneous left main coronary artery dissection

    Directory of Open Access Journals (Sweden)

    Alptug Tokatli

    2016-03-01

    Full Text Available Spontaneous coronary artery dissection (SCAD is a very rare clinical condition. Physiopathology of SCAD is still mostly unclear. Clinical presentation of SCAD ranges from atypical symptoms to sudden cardiac death. The diagnosis of dissection is generally made by using conventional coronary angiography. Invasive or conservative treatment is reasonable.

  13. Spontaneous extracranial decompression of epidural hematoma

    International Nuclear Information System (INIS)

    Neely, John C.; Jones, Blaise V.; Crone, Kerry R.

    2008-01-01

    Epidural hematoma (EDH) is a common sequela of head trauma in children. An increasing number are managed nonsurgically, with close clinical and imaging observation. We report the case of a traumatic EDH that spontaneously decompressed into the subgaleal space, demonstrated on serial CT scans that showed resolution of the EDH and concurrent enlargement of the subgaleal hematoma. (orig.)

  14. Spontaneous extracranial decompression of epidural hematoma

    Energy Technology Data Exchange (ETDEWEB)

    Neely, John C. [Marshall University School of Medicine, Huntington, WV (United States); Jones, Blaise V. [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Crone, Kerry R. [Cincinnati Children' s Hospital Medical Center, Division of Neurosurgery, Cincinnati, OH (United States)

    2008-03-15

    Epidural hematoma (EDH) is a common sequela of head trauma in children. An increasing number are managed nonsurgically, with close clinical and imaging observation. We report the case of a traumatic EDH that spontaneously decompressed into the subgaleal space, demonstrated on serial CT scans that showed resolution of the EDH and concurrent enlargement of the subgaleal hematoma. (orig.)

  15. Spontaneous Sourcing among Students Reading Multiple Documents

    Science.gov (United States)

    Stromso, Helge I.; Braten, Ivar; Britt, M. Anne; Ferguson, Leila E.

    2013-01-01

    This study used think-aloud methodology to explore undergraduates' spontaneous attention to and use of source information while reading six documents that presented conflicting views on a controversial social scientific issue in a Google-like environment. Results showed that students explicitly and implicitly paid attention to sources of documents…

  16. Massive Spontaneous Hemothorax, Giant Intrathoracic Meningocele ...

    African Journals Online (AJOL)

    haemothorax associated with von Recklinghausen's disease: Review of occurrence in Japan. Thorax 1997;52:575‑8. 3. Fedoruk LM, English J, Fradet GJ. Spontaneous hemothorax and neurofibromatosis: A review of a lethal combination. Asian Cardiovasc. Thorac Ann 2007;15:342‑4. 4. Conlon NP, Redmond KC, Celi LA.

  17. A Fatal Complication of Dermatomyositis: Spontaneous Pneumomediastinum

    Directory of Open Access Journals (Sweden)

    Ezgi Demirdöğen Çetinoğlu

    2016-04-01

    Full Text Available Interstitial lung disease (ILD is a negative prognostic factor associated with increased morbidity and mortality in patients with dermatomyositis (DM. Spontaneous pneumomediastinum is a rare complication of DM and it can be fatal. We present a 48-year-old woman with DM and ILD complicated by pneumomediastinum without pneumothorax and subcutaneous emphysema.

  18. Grooming behavior of spontaneously hypertensive rats

    NARCIS (Netherlands)

    Buuse, M. van den; Jong, Wybren de

    1987-01-01

    In an open field spontaneously hypertensive rats (SHR) exhibited lower scores for grooming when compared to their normotensive controls, the Wistar Kyoto rats (WKY). After i.c.v. injection of 1 μg ACTH1–24 cumulative 50-min grooming scores were lower in SHR. Analysis of subscores indicated that the

  19. Spontaneous abortion and physical strain around implantation

    DEFF Research Database (Denmark)

    Hjollund, N H; Jensen, Tina Kold; Bonde, Jens Peter

    2000-01-01

    Existing studies of physical strain and spontaneous abortion are mainly retrospective or based only on pregnancies that have survived the first trimester. Furthermore, almost all studies have relied on averaged measures of physical strain, which tend to blur an effect if peak values during short ...

  20. Spontaneous Hedonic Reactions to Social Media Cues.

    Science.gov (United States)

    van Koningsbruggen, Guido M; Hartmann, Tilo; Eden, Allison; Veling, Harm

    2017-05-01

    Why is it so difficult to resist the desire to use social media? One possibility is that frequent social media users possess strong and spontaneous hedonic reactions to social media cues, which, in turn, makes it difficult to resist social media temptations. In two studies (total N = 200), we investigated less-frequent and frequent social media users' spontaneous hedonic reactions to social media cues using the Affect Misattribution Procedure-an implicit measure of affective reactions. Results demonstrated that frequent social media users showed more favorable affective reactions in response to social media (vs. control) cues, whereas less-frequent social media users' affective reactions did not differ between social media and control cues (Studies 1 and 2). Moreover, the spontaneous hedonic reactions to social media (vs. control) cues were related to self-reported cravings to use social media and partially accounted for the link between social media use and social media cravings (Study 2). These findings suggest that frequent social media users' spontaneous hedonic reactions in response to social media cues might contribute to their difficulties in resisting desires to use social media.

  1. Spontaneous electric fields in solid films: spontelectrics

    DEFF Research Database (Denmark)

    Field, David; Plekan, Oksana; Cassidy, Andrew

    2013-01-01

    When dipolar gases are condensed at sufficiently low temperature onto a solid surface, they form films that may spontaneously exhibit electric fields in excess of 108V/m. This effect, called the ‘spontelectric effect’, was recently revealed using an instrument designed to measure scattering...

  2. Spontaneous Retroperitoneal Hemorrhage from Adrenal Artery Aneurysm

    International Nuclear Information System (INIS)

    Gonzalez Valverde, F.M.; Balsalobre, M.; Torregrosa, N.; Molto, M.; Gomez Ramos, M.J.; Vazquez Rojas, J.L.

    2007-01-01

    Spontaneous adrenal hemorrhage is a very rare but serious disorder of the adrenal gland that can require emergent treatment. We report on a 42-year-old man who underwent selective angiography for diagnosis and treatment of retroperitoneal hemorrhage from small adrenal artery aneurysm. This case gives further details about the value of transluminal artery embolization in the management of visceral aneurysm rupture

  3. Individual differences in spontaneous analogical transfer.

    Science.gov (United States)

    Kubricht, James R; Lu, Hongjing; Holyoak, Keith J

    2017-05-01

    Research on analogical problem solving has shown that people often fail to spontaneously notice the relevance of a semantically remote source analog when solving a target problem, although they are able to form mappings and derive inferences when given a hint to recall the source. Relatively little work has investigated possible individual differences that predict spontaneous transfer, or how such differences may interact with interventions that facilitate transfer. In this study, fluid intelligence was measured for participants in an analogical problem-solving task, using an abridged version of the Raven's Progressive Matrices (RPM) test. In two experiments, we systematically compared the effect of augmenting verbal descriptions of the source with animations or static diagrams. Solution rates to Duncker's radiation problem were measured across varying source presentation conditions, and participants' understanding of the relevant source material was assessed. The pattern of transfer was best fit by a moderated mediation model: the positive impact of fluid intelligence on spontaneous transfer was mediated by its influence on source comprehension; however, this path was in turn modulated by provision of a supplemental animation via its influence on comprehension of the source. Animated source depictions were most beneficial in facilitating spontaneous transfer for those participants with low scores on the fluid intelligence measure.

  4. Spontaneous regression of a mandibular arteriovenous malformation

    Directory of Open Access Journals (Sweden)

    Scott B. Raymond, MD, PhD

    2015-06-01

    Full Text Available Mandibular arteriovenous malformations (AVMs are rare lesions that may initially present as catastrophic bleeding during dental surgical procedures. Owing to the significant risk of bleeding, most mandibular AVMs are treated definitively by resection or embolization. In this report, we describe a mandibular AVM that spontaneously regressed after biopsy.

  5. Unified gauge theories with spontaneous symmetry breaking

    International Nuclear Information System (INIS)

    MacDowell, S.W.

    1975-01-01

    Unified gauge theories with spontaneous symmetry breaking are studied with a view to renormalize quantum field theory. Georgi-Glashow and Weinberg-Salam models to unify weak and electromagnetic interactions are discussed in detail. Gauge theories of strong interactions are also considered [pt

  6. Influence of spontaneous fermentation on some quality ...

    African Journals Online (AJOL)

    Spontaneous fermentation has been identified to improve the quality characteristics of foods derived from them. When combined with cowpea fortification and nixtamalization, it is expected to improve the nutritional, functional, physico- chemical and sensory qualities of maize based foods thereby improving the qualities as ...

  7. Maternal Factors Associated With Early Spontaneous Singleton ...

    African Journals Online (AJOL)

    Background: Knowledge of the maternal factors predisposing to preterm deliveries should affect the anticipatory care of mothers at risk of delivering preterm babies and improve perinatal outcome. Objective: To determine the maternal socio-biological characteristics associated with the delivery of early spontaneous ...

  8. Spontaneous sensorimotor coupling with multipart music.

    Science.gov (United States)

    Hurley, Brian K; Martens, Peter A; Janata, Petr

    2014-08-01

    Music often evokes spontaneous movements in listeners that are synchronized with the music, a phenomenon that has been characterized as being in "the groove." However, the musical factors that contribute to listeners' initiation of stimulus-coupled action remain unclear. Evidence suggests that newly appearing objects in auditory scenes orient listeners' attention, and that in multipart music, newly appearing instrument or voice parts can engage listeners' attention and elicit arousal. We posit that attentional engagement with music can influence listeners' spontaneous stimulus-coupled movement. Here, 2 experiments-involving participants with and without musical training-tested the effect of staggering instrument entrances across time and varying the number of concurrent instrument parts within novel multipart music on listeners' engagement with the music, as assessed by spontaneous sensorimotor behavior and self-reports. Experiment 1 assessed listeners' moment-to-moment ratings of perceived groove, and Experiment 2 examined their spontaneous tapping and head movements. We found that, for both musically trained and untrained participants, music with more instruments led to higher ratings of perceived groove, and that music with staggered instrument entrances elicited both increased sensorimotor coupling and increased reports of perceived groove. Although untrained participants were more likely to rate music as higher in groove, trained participants showed greater propensity for tapping along, and they did so more accurately. The quality of synchronization of head movements with the music, however, did not differ as a function of training. Our results shed new light on the relationship between complex musical scenes, attention, and spontaneous sensorimotor behavior.

  9. Formation of oil-in-water emulsions from natural emulsifiers using spontaneous emulsification: sunflower phospholipids.

    Science.gov (United States)

    Komaiko, Jennifer; Sastrosubroto, Ashtri; McClements, David Julian

    2015-11-18

    This study examined the possibility of producing oil-in-water emulsions using a natural surfactant (sunflower phospholipids) and a low-energy method (spontaneous emulsification). Spontaneous emulsification was carried out by titrating an organic phase (oil and phospholipid) into an aqueous phase with continuous stirring. The influence of phospholipid composition, surfactant-to-oil ratio (SOR), initial phospholipids location, storage time, phospholipid type, and preparation method was tested. The initial droplet size depended on the nature of the phospholipid used, which was attributed to differences in phospholipid composition. Droplet size decreased with increasing SOR and was smallest when the phospholipid was fully dissolved in the organic phase rather than the aqueous phase. The droplets formed using spontaneous emulsification were relatively large (d > 10 μm), and so the emulsions were unstable to gravitational separation. At low SORs (0.1 and 0.5), emulsions produced with phospholipids had a smaller particle diameter than those produced with a synthetic surfactant (Tween 80), but at a higher SOR (1.0), this trend was reversed. High-energy methods (microfluidization and sonication) formed significantly smaller droplets (d < 10 μm) than spontaneous emulsification. The results from this study show that low-energy methods could be utilized with natural surfactants for applications for which fine droplets are not essential.

  10. Large scientific releases

    International Nuclear Information System (INIS)

    Pongratz, M.B.

    1981-01-01

    The motivation for active experiments in space is considered, taking into account the use of active techniques to obtain a better understanding of the natural space environment, the utilization of the advantages of space as a laboratory to study fundamental plasma physics, and the employment of active techniques to determine the magnitude, degree, and consequences of artificial modification of the space environment. It is pointed out that mass-injection experiments in space plasmas began about twenty years ago with the Project Firefly releases. Attention is given to mass-release techniques and diagnostics, operational aspects of mass release active experiments, the active observation of mass release experiments, active perturbation mass release experiments, simulating an artificial modification of the space environment, and active experiments to study fundamental plasma physics

  11. Energies; Energies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    In the framework of the National Debate on the energies in a context of a sustainable development some associations for the environment organized a debate on the nuclear interest facing the renewable energies. The first part presents the nuclear energy as a possible solution to fight against the greenhouse effect and the associated problem of the wastes management. The second part gives information on the solar energy and the possibilities of heat and electric power production. A presentation of the FEE (French wind power association) on the situation and the development of the wind power in France, is also provided. (A.L.B.)

  12. Co-Occurrence of Chronic Spontaneous Urticaria with Immunoglobulin A Deficiency and Autoimmune Diseases.

    Science.gov (United States)

    Frossi, Barbara; De Carli, Stefano; Bossi, Fleur; Pucillo, Carlo; De Carli, Marco

    2016-01-01

    Immunoglobulin (Ig) A deficiency is a primary immunodeficiency in which autoimmunity is frequently observed. Thirty to fifty percent of patients with spontaneous chronic urticaria have autoantibodies that are able to cross-link FcεRI on mast cells and basophils. We investigated whether spontaneous chronic urticaria in patients with IgA deficiency meets the criteria for autoimmunity. Four patients were screened for positivity to a skin prick test and an autologous serum skin test and for the presence of other autoimmune diseases. Patient sera were tested for the ability to activate basophils and mast cells in vitro by measuring surface CD63 expression and β-hexosaminidase release, respectively. The autologous serum test was positive in all patients, and patient sera were found to induce CD63 upregulation on basophils and degranulation of an LAD2 mast cell line. Moreover, all patients were affected by other autoimmune disorders. For the first time, these data point out chronic autoimmune urticaria in subjects with an IgA deficiency and confirm that different autoimmune disorders are common among patients with an IgA deficiency. Patients with chronic autoimmune spontaneous urticaria should be screened for IgA deficiency, especially if they are affected by other autoimmune disorders. Thus, spontaneous urticaria could mirror more complex systemic diseases, such as immune deficiency. © 2016 S. Karger AG, Basel.

  13. Quantum theory of spontaneous and stimulated emission of surface plasmons

    International Nuclear Information System (INIS)

    Archambault, Alexandre; Marquier, Francois; Greffet, Jean-Jacques; Arnold, Christophe

    2010-01-01

    We introduce a quantization scheme that can be applied to surface waves propagating along a plane interface. An important result is the derivation of the energy of the surface wave for dispersive nonlossy media without invoking any specific model for the dielectric constant. Working in Coulomb's gauge, we use a modal representation of the fields. Each mode can be associated with a quantum harmonic oscillator. We have applied the formalism to derive quantum mechanically the spontaneous emission rate of surface plasmon by a two-level system. The result is in very good agreement with Green's tensor approach in the nonlossy case. Green's approach allows also to account for losses, so that the limitations of a quantum approach of surface plasmons are clearly defined. Finally, the issue of stimulated versus spontaneous emission has been addressed. Because of the increasing density of states near the asymptote of the dispersion relation, it is quantitatively shown that the stimulated emission probability is too small to obtain gain in this frequency region.

  14. Spontaneous emission spectra from a staggered-array undulator

    International Nuclear Information System (INIS)

    Shimada, Shigeki; Okada, Kouji; Masuda, Kai; Sobajima, Masaaki; Yoshikawa, Kiyoshi; Ohnishi, Masami; Yamamoto, Yasushi; Toku, Hisayuki

    1997-01-01

    A staggered-array undulator set inside the superconducting solenoid coils is shown to be able to provide high undulator fields larger than the longitudinal magnetic fields, a small undulator period, easy tunability through the solenoid coil current, and compact and easy fabrication. The overall performance characteristics of this undulator were studied mainly with respect to iron and aluminum disk widths, and spontaneous emission spectra through the numerical calculations. The maximum undulator field is found to be obtained for the ratio of the aluminum disk width to the undulator period of 0.45. The line widths (FWHM) of the spontaneous emission spectra, however, do not show N w -1 dependence on the number of the undulator period N w for practical beams with a Gaussian distribution, compared with for a single electron. The energy spread among various parameters is seen to play an important role in reducing the FWHM with increase of N w . The large tunability of the wavelength is proved to cover 6-10 mm by changing the solenoid magnetic field from 0.4 T to 1.6 T. (author)

  15. Minimally doubled fermions and spontaneous chiral symmetry breaking

    Directory of Open Access Journals (Sweden)

    Osmanaj (Zeqirllari Rudina

    2018-01-01

    Full Text Available Chiral symmetry breaking in massless QCD is a very important feature in the current understanding of low energy physics. Low - lying Dirac modes are suitable to help us understand the spontaneous chiral symmetry breaking, since the formation of a non zero chiral condensate is an effect of their accumulation near zero. The Banks – Casher relation links the spectral density of the Dirac operator to the condensate with an identity that can be read in both directions. In this work we propose a spectral method to achieve a reliable determination of the density of eigenvalues of Dirac operator near zero using the Gauss – Lanczos quadrature. In order to understand better the dynamical chiral symmetry breaking and use the method we propose, we have chosen to work with minimally doubled fermions. These kind of fermions have been proposed as a strictly local discretization of the QCD fermions action, which preserves chiral symmetry at finite cut-off. Being chiral fermions, is easier to work with them and their low - lying Dirac modes and to understand the dynamical spontaneous chiral symmetry breaking.

  16. Minimally doubled fermions and spontaneous chiral symmetry breaking

    Science.gov (United States)

    Osmanaj (Zeqirllari), Rudina; Hyka (Xhako), Dafina

    2018-03-01

    Chiral symmetry breaking in massless QCD is a very important feature in the current understanding of low energy physics. Low - lying Dirac modes are suitable to help us understand the spontaneous chiral symmetry breaking, since the formation of a non zero chiral condensate is an effect of their accumulation near zero. The Banks - Casher relation links the spectral density of the Dirac operator to the condensate with an identity that can be read in both directions. In this work we propose a spectral method to achieve a reliable determination of the density of eigenvalues of Dirac operator near zero using the Gauss - Lanczos quadrature. In order to understand better the dynamical chiral symmetry breaking and use the method we propose, we have chosen to work with minimally doubled fermions. These kind of fermions have been proposed as a strictly local discretization of the QCD fermions action, which preserves chiral symmetry at finite cut-off. Being chiral fermions, is easier to work with them and their low - lying Dirac modes and to understand the dynamical spontaneous chiral symmetry breaking.

  17. Spontaneous excitation of a static multilevel atom coupled with electromagnetic vacuum fluctuations in Schwarzschild spacetime

    International Nuclear Information System (INIS)

    Zhou Wenting; Yu Hongwei

    2012-01-01

    We study the spontaneous excitation of a radially polarized static multilevel atom outside a spherically symmetric black hole in multipolar interaction with quantum electromagnetic fluctuations in the Boulware, Unruh and Hartle-Hawking vacuum states. We find that spontaneous excitation does not occur in the Boulware vacuum, and, in contrast to the scalar field case, the spontaneous emission rate is not well behaved at the event horizon as a result of the blow-up of the proper acceleration of the static atom. However, spontaneous excitation can take place both in the Unruh and the Hartle-Hawking vacua as if there were thermal radiation from the black hole. Distinctive features in contrast to the scalar field case are the existence of a term proportional to the proper acceleration squared in the rate of change of the mean atomic energy in the Unruh and the Hartle-Hawking vacua and the structural similarity in the spontaneous excitation rate between the static atoms outside a black hole and uniformly accelerated ones in a flat space with a reflecting boundary, which is particularly dramatic at the event horizon where a complete equivalence exists. (paper)

  18. Multifractal fluctuations in joint angles during infant spontaneous kicking reveal multiplicativity-driven coordination

    International Nuclear Information System (INIS)

    Stephen, Damian G.; Hsu, Wen-Hao; Young, Diana; Saltzman, Elliot L.; Holt, Kenneth G.; Newman, Dava J.; Weinberg, Marc; Wood, Robert J.; Nagpal, Radhika; Goldfield, Eugene C.

    2012-01-01

    Previous research has considered infant spontaneous kicking as a form of exploration. According to this view, spontaneous kicking provides information about motor degrees of freedom and may shape multijoint coordinations for more complex movement patterns such as gait. Recent work has demonstrated that multifractal, multiplicative fluctuations in exploratory movements index energy flows underlying perceptual-motor information. If infant spontaneous kicking is exploratory and occasions an upstream flow of information from the motor periphery, we expected not only that multiplicativity of fluctuations at the hip should promote multiplicativity of fluctuations at more distal joints (i.e., reflecting downstream effects of neural control) but also that multiplicativity at more distal joints should promote multiplicativity at the hip. Multifractal analysis demonstrated that infant spontaneous kicking in four typically developing infants for evidence of multiplicative fluctuations in multiple joint angles along the leg (i.e., hip, knee, and ankle) exhibited multiplicativity. Vector autoregressive modeling demonstrated that only one leg exhibited downstream effects but that both legs exhibited upstream effects. These results confirm the exploratory aspect of infant spontaneous kicking and suggest chaotic dynamics in motor coordination. They also resonate with existing models of chaos-controlled robotics and noise-based interventions for rehabilitating motor coordination in atypically developing patients.

  19. Socioeconomic position and the risk of spontaneous abortion

    DEFF Research Database (Denmark)

    Norsker, Filippa Nyboe; Espenhain, Laura; rogvi, Sofie

    2012-01-01

    To investigate the relationship between different indicators of socioeconomic position and the risk of spontaneous abortion.......To investigate the relationship between different indicators of socioeconomic position and the risk of spontaneous abortion....

  20. Energy production in stars

    International Nuclear Information System (INIS)

    Bethe, Hans.

    1977-01-01

    Energy in stars is released partly by gravitation, partly by nuclear reactions. For ordinary stars like our sun, nuclear reactions predominate. However, at the end of the life of a star very large amounts of energy are released by gravitational collapse; this can amount to as much as 10 times the total energy released nuclear reactions. The rotational energy of pulsars is a small remnant of the energy of gravitation. The end stage of small stars is generally a white dwarf, of heavy stars a neutron star of possibly a black hole

  1. [Bacterial vaginosis and spontaneous preterm birth].

    Science.gov (United States)

    Brabant, G

    2016-12-01

    To determine if bacterial vaginosis is a marker for risk of spontaneous preterm delivery and if its detection and treatment can reduce this risk. Consultation of the database Pubmed/Medline, Science Direct, and international guidelines of medical societies. Bacterial vaginosis (BV) is a dysbiosis resulting in an imbalance in the vaginal flora through the multiplication of anaerobic bacteria and jointly of a disappearance of well-known protective Lactobacilli. His diagnosis is based on clinical Amsel criteria and/or a Gram stain with establishment of the Nugent score. The prevalence of the BV extraordinarily varies according to ethnic and/or geographical origin (4-58 %), in France, it is close to 7 % in the first trimester of pregnancy (EL2). The link between BV and spontaneous premature delivery is low with an odds ratio between 1.5 and 2 in the most recent studies (EL3). Metronidazole or clindamycin is effective to treat BV (EL3). It is recommended to prescribe one of these antibiotics in the case of symptomatic BV (Professional Consensus). The testing associated with the treatment of BV in the global population showed no benefit in the prevention of the risk of spontaneous preterm delivery (EL2). Concerning low-risk asymptomatic population (defined by the absence of antecedent of premature delivery), it has been failed profit to track and treat the BV in the prevention of the risk of spontaneous preterm delivery (EL1). Concerning the high-risk population (defined by a history of preterm delivery), it has been failed profit to track and treat the VB in the prevention of the risk of spontaneous preterm delivery (EL3). However, in the sub population of patients with a history of preterm delivery occurred in a context of materno-fetal bacterial infection, there may be a benefit to detect and treat early and systematically genital infection, and in particular the BV (Professional Consensus). The screening and treatment of BV during pregnancy in asymptomatic low

  2. Mobile energy sharing futures

    DEFF Research Database (Denmark)

    Worgan, Paul; Knibbe, Jarrod; Plasencia, Diego Martinez

    2016-01-01

    We foresee a future where energy in our mobile devices can be shared and redistributed to suit our current task needs. Many of us are beginning to carry multiple mobile devices and we seek to re-evaluate the traditional view of a mobile device as only accepting energy. In our vision, we can...... leverage the energy stored in our devices to wirelessly distribute energy between our friends, family, colleagues and strangers devices. In this paper we explore the opportunities and interactions presented by such spontaneous energy transfer interactions and present some envisaged collaborative energy...

  3. Microscopic Phase-Space Exploration Modeling of ^{258}Fm Spontaneous Fission.

    Science.gov (United States)

    Tanimura, Yusuke; Lacroix, Denis; Ayik, Sakir

    2017-04-14

    We show that the total kinetic energy (TKE) of nuclei after the spontaneous fission of ^{258}Fm can be well reproduced using simple assumptions on the quantum collective phase space explored by the nucleus after passing the fission barrier. Assuming energy conservation and phase-space exploration according to the stochastic mean-field approach, a set of initial densities is generated. Each density is then evolved in time using the nuclear time-dependent density-functional theory with pairing. This approach goes beyond the mean-field theory by allowing spontaneous symmetry breaking as well as a wider dynamical phase-space exploration leading to larger fluctuations in collective space. The total kinetic energy and mass distributions are calculated. New information on the fission process: fluctuations in scission time, strong correlation between TKE and collective deformation, as well as prescission particle emission, are obtained. We conclude that fluctuations of the TKE and mass are triggered by quantum fluctuations.

  4. F. VON HAYEK’S THEORY OF SPONTANEOUS ORDER

    Directory of Open Access Journals (Sweden)

    О. Nesterenko

    2013-04-01

    Full Text Available The essence and the genesis of spontaneous order are disclosed in the context of critical analysis of constructivism. The author’s approach to the definition of the characteristic features of the spontaneous order is proposed. The dichotomy of the order is revealed towards the economic sphere in form of spontaneous order and organization.

  5. [Spontaneous renal artery dissection: a case report].

    Science.gov (United States)

    Maehana, Takeshi; Nishida, Sachiyo; Shindo, Tetsuya; Miyamoto, Shintaro; Muranaka, Takashi; Suzuki, Kazuhiro; Yanase, Masahiro

    2008-01-01

    A 65-year-old female was admitted to our hospital complaining of left upper abdominal pain. Although the symptom improved with observation, serum creatinine rose to 2.0 mg/dl. Slight atrophy of the left kidney was seen on abdominal plain computed tomography. In order to examine the possibility of renal infarction from thrombosis with angiography, we consulted the department of cardiovascular medicine. Even though we did not detect thrombosis with left renal angiography or intravascular ultrasound, there was a dissection finding localized at the left renal artery. Based on this finding, we made a diagnosis of spontaneous renal artery dissection and performed stent placement. Spontaneous renal artery dissection is extremely rare and the frequency of occurrence is reported to be less than 0.05%. Recently, however the frequency of detection has risen with the development of clinical imaging. We must keep in mind that the condition has the possibility of leading to renal blood circulation disorders.

  6. Thermal influences on spontaneous rock dome exfoliation

    Science.gov (United States)

    Collins, Brian D.; Stock, Greg M.; Eppes, Martha C.; Lewis, Scott W.; Corbett, Skye C.; Smith, Joel B.

    2018-01-01

    Rock domes, with their onion-skin layers of exfoliation sheets, are among the most captivating landforms on Earth. Long recognized as integral in shaping domes, the exact mechanism(s) by which exfoliation occurs remains enigmatic, mainly due to the lack of direct observations of natural events. In August 2014, during the hottest days of summer, a granitic dome in California, USA, spontaneously exfoliated; witnesses observed extensive cracking, including a ~8000 kg sheet popping into the air. Subsequent exfoliation episodes during the following two summers were recorded by instrumentation that captured—for the first time—exfoliation deformation and stress conditions. Here we show that thermal cycling and cumulative dome surface heating can induce subcritical cracking that culminates in seemingly spontaneous exfoliation. Our results indicate that thermal stresses—largely discounted in dome formation literature—can play a key role in triggering exfoliation and therefore may be an important control for shaping domes worldwide.

  7. Spontaneous abortion and physical strain around implantation

    DEFF Research Database (Denmark)

    Hjøllund, Niels Henrik Ingvar; Jensen, T.K.; Bonde, J.P.

    2000-01-01

    Existing studies of physical strain and spontaneous abortion are mainly retrospective or based only on pregnancies that have survived the first trimester. Furthermore, almost all studies have relied on averaged measures of physical strain, which tend to blur an effect if peak values during short...... time periods are the relevant measure. We followed a cohort of first pregnancy planners from termination of birth control until pregnancy for a maximum of six menstrual cycles. The analyses include 181 pregnancies, of which 32 were subclinical pregnancies detected by hCG analysis only. During early...... pregnancy the women recorded physical strain prospectively in a structured diary. Physical strain around the time of implantation was associated with later spontaneous abortion. The adjusted risk ratio for women who reported physical strain higher than average at day 6 to 9 after the estimated date...

  8. Spontaneous Enterocutaneous Fistula Resulting from Richter's Hernia.

    Science.gov (United States)

    Hajong, Ranendra; Khongwar, Donkupar; Komut, Ojing; Naku, Narang; Baru, Kappa

    2017-08-01

    Richter's hernia is due to the entrapment of a part of circumference of the bowel wall. As the bowel continuity is maintained, the patients usually do not have intestinal obstruction. Some patients with Richter's hernia may present with enterocutaneous fistula either spontaneous or due to surgical intervention mistaking the obstructed hernia to be inguinal abscess. This is more so in developing countries due to lack of awareness among the masses or due to the delay in seeking medical attention. Presenting here is a case of a 53-year-old male patient with enterocutaneous fistula which occurred spontaneously and sought medical attention only after about three years of repeated discharge of yellowish fluid from the left inguinal region. Magnetic resonance fistulogram confirmed the diagnosis of enterocutaneous fistula. Laparotomy with resection and primary anastomosis of the fistulous bowel was done. Patient recovered uneventfully without any complications or recurrence.

  9. Spontaneous Coronary Artery Dissection and Pregnancy.

    Science.gov (United States)

    Naderi, Sahar

    2017-09-01

    Spontaneous coronary artery dissection (SCAD) is a non-atherosclerotic, non-traumatic cause of coronary artery dissection. SCAD is the most common cause of myocardial infarction in pregnancy or the postpartum period and results in significant cardiovascular morbidity and mortality in the pregnant population. It is important to consider pregnancy-associated spontaneous coronary artery dissection (PASCAD) high on the differential for a pregnant woman who presents with symptoms consistent with acute coronary syndrome. Management of these patients requires a thoughtful, multidisciplinary approach, with consideration of conservative management if possible. Counseling regarding future pregnancies is also critical and requires compassionate care. Given our limited understanding of SCAD, including PASCAD, more data and research are needed to help guide diagnosis, management, and determination of prognosis.

  10. Spontaneous stress fractures of the femoral neck

    International Nuclear Information System (INIS)

    Dorne, H.L.; Lander, P.H.

    1985-01-01

    The diagnosis of spontaneous stress fractures of the femoral neck, a form of insufficiency stress fracture, can be missed easily. Patients present with unremitting hip pain without a history of significant trauma or unusual increase in daily activity. The initial radiographic features include osteoporosis, minor alterations of trabecular alignment, minimal extracortical or endosteal reaction, and lucent fracture lines. Initial scintigraphic examinations performed in three of four patients showed focal increased radionuclide uptake in two and no focal abnormality in one. Emphasis is placed on the paucity of early findings. Evaluation of patients with persistent hip pain requires a high degree of clinical suspicion and close follow-up; the sequelae of undetected spontaneous fractures are subcapital fracture with displacement, angular deformity, and a vascular necrosis of the femoral head

  11. Motivational Projections of Russian Spontaneous Speech

    Directory of Open Access Journals (Sweden)

    Galina M. Shipitsina

    2017-06-01

    Full Text Available The article deals with the semantic, pragmatic and structural features of words, phrases, dialogues motivation, in the contemporary Russian popular speech. These structural features are characterized by originality and unconventional use. Language material is the result of authors` direct observation of spontaneous verbal communication between people of different social and age groups. The words and remarks were analyzed in compliance with the communication system of national Russian language and cultural background of popular speech. Studies have discovered that in spoken discourse there are some other ways to increase the expression statement. It is important to note that spontaneous speech identifies lacunae in the nominative language and its vocabulary system. It is proved, prefixation is also effective and regular way of the same action presenting. The most typical forms, ways and means to update language resources as a result of the linguistic creativity of native speakers were identified.

  12. PERMETHRIN BUT NOT DELTAMETHRIN INCREASES SPONTANEOUS GLUTAMATE RELEASE FROM HIPPOCAMPAL NEURONS IN CULTURE.

    Science.gov (United States)

    This manuscript provides important information relevant to the cumulative risk assessment of pyrethroid insecticides. Others have proposed that pyrethroid effects on voltage-gated calcium channels contribute the neurotoxicity and must be considered in cumulative risk assessments ...

  13. ACTIONS OF PYRETHROID INSECTICIDES ON THE SPONTANEOUS RELEASE OF GLUTAMATE FROM CULTURED HIPPOCAMPAL NEURONS.

    Science.gov (United States)

    Pyrethroid insecticides increase the excitability of the central and peripheral nervous systems. Modulation of voltage-gated sodium channels is likely to play a primary role in this effect, but recent studies have suggested that pyrethroid effects on other ion channels may contri...

  14. Dependence of spontaneous electrical activity and basal prolactin release on nonselective cation channels in pituitary lactotrophs

    Czech Academy of Sciences Publication Activity Database

    Kučka, M.; Kretschmannová, K.; Stojilkovic, S. S.; Zemková, Hana; Tomic, M.

    2012-01-01

    Roč. 61, č. 3 (2012), s. 267-275 ISSN 0862-8408 R&D Projects: GA ČR(CZ) GA305/07/0681; GA ČR(CZ) GBP304/12/G069 Institutional research plan: CEZ:AV0Z50110509 Institutional support: RVO:67985823 Keywords : TRPC channels * pituitary * GH3 cells * calcium influx * action potentials * resting membrane potential Subject RIV: ED - Physiology Impact factor: 1.531, year: 2012

  15. Spontaneous pneumomediastinum due to paralytic rabies

    Directory of Open Access Journals (Sweden)

    Wuping Wang

    2013-02-01

    Full Text Available Rabies is a fatal disease resulting from rabies virus infection, causing severe neurological symptoms and ultimately death by destroying the nervous system. In general, a patient tends to see a neurologist or an infectious diseases physician, with very common and typical discipline-related signs and symptoms, such as hydrophobia, aerophobia, and mental disorders. However, we reported a rabies patient who was first admitted to see a thoracic surgeon with spontaneous pneumomediastinum.

  16. Spontaneous pneumomediastinum due to paralytic rabies

    Directory of Open Access Journals (Sweden)

    Wuping Wang

    Full Text Available Rabies is a fatal disease resulting from rabies virus infection, causing severe neurological symptoms and ultimately death by destroying the nervous system. In general, a patient tends to see a neurologist or an infectious diseases physician, with very common and typical discipline-related signs and symptoms, such as hydrophobia, aerophobia, and mental disorders. However, we reported a rabies patient who was first admitted to see a thoracic surgeon with spontaneous pneumomediastinum.

  17. Quantum mechanics with spontaneous localization and experiments

    International Nuclear Information System (INIS)

    Benatti, F.; Grassi, R.

    1994-05-01

    We examine from an experimental point of view the recently proposed models of spontaneous reduction. We compare their implications about decoherence with those of environmental effects. We discuss the treatment, within the considered models, of the so called quantum telegraph phenomenon and we show that, contrary to what has been recently stated, no problems are met. Finally, we review recent interesting work investigating the implications of dynamical reduction for the proton decay. (author). 16 refs, 4 figs, 3 tabs

  18. Spontaneous atlantoaxial subluxation associated with tonsillitis

    OpenAIRE

    Shunmugam, Meenalochani; Poonnoose, Santosh

    2015-01-01

    Atlantoaxial subluxation is a rare condition and requires a high index of suspicion to diagnose and treat in order to avoid long-term sequelae. Here, we present a case of late presentation of a nontraumatic rotatory subluxation of the atlantoaxial joint or atlantoaxial rotatory subluxation. A 17-year-old girl presented 3 months after the onset of nonspecific upper limb sensory symptoms which eventually settled spontaneously. Initial conservative management by the general practitioner had no e...

  19. Miniature Release Mechanism Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective is to design, build and functionally test a miniature release mechanism for CubeSats and other small satellites. The WFF 6U satellite structure will be...

  20. Spontaneous Regression of a Cervical Disk Herniation

    Directory of Open Access Journals (Sweden)

    Emre Delen

    2014-03-01

    Full Text Available A 54 years old female patient was admitted to our outpatient clinic with a two months history of muscle spasms of her neck and pain radiating to the left upper extremity. Magnetic resonance imaging had shown a large left-sided paracentral disk herniation at the C6-C7 disk space (Figure 1. Neurological examination showed no obvious neurological deficit. She received conservative treatment including bed rest, rehabilitation, and analgesic drugs. After 13 months, requested by the patient, a second magnetic resonance imaging study showed resolution of the disc herniation.(Figure 2 Although the literature contains several reports about spontaneous regression of herniated lumbar disc without surgical intervention, that of phenomenon reported for herniated cervical level is rare, and such reports are few[1]. In conclusion, herniated intervertebral disc have the potential to spontaneously regress independently from the spine level. With further studies, determining the predictive signs for prognostic evaluation for spontaneous regression which would yield to conservative treatment would be beneficial.

  1. Spontaneously emerging cortical representations of visual attributes

    Science.gov (United States)

    Kenet, Tal; Bibitchkov, Dmitri; Tsodyks, Misha; Grinvald, Amiram; Arieli, Amos

    2003-10-01

    Spontaneous cortical activity-ongoing activity in the absence of intentional sensory input-has been studied extensively, using methods ranging from EEG (electroencephalography), through voltage sensitive dye imaging, down to recordings from single neurons. Ongoing cortical activity has been shown to play a critical role in development, and must also be essential for processing sensory perception, because it modulates stimulus-evoked activity, and is correlated with behaviour. Yet its role in the processing of external information and its relationship to internal representations of sensory attributes remains unknown. Using voltage sensitive dye imaging, we previously established a close link between ongoing activity in the visual cortex of anaesthetized cats and the spontaneous firing of a single neuron. Here we report that such activity encompasses a set of dynamically switching cortical states, many of which correspond closely to orientation maps. When such an orientation state emerged spontaneously, it spanned several hypercolumns and was often followed by a state corresponding to a proximal orientation. We suggest that dynamically switching cortical states could represent the brain's internal context, and therefore reflect or influence memory, perception and behaviour.

  2. Spontaneous prediction error generation in schizophrenia.

    Directory of Open Access Journals (Sweden)

    Yuichi Yamashita

    Full Text Available Goal-directed human behavior is enabled by hierarchically-organized neural systems that process executive commands associated with higher brain areas in response to sensory and motor signals from lower brain areas. Psychiatric diseases and psychotic conditions are postulated to involve disturbances in these hierarchical network interactions, but the mechanism for how aberrant disease signals are generated in networks, and a systems-level framework linking disease signals to specific psychiatric symptoms remains undetermined. In this study, we show that neural networks containing schizophrenia-like deficits can spontaneously generate uncompensated error signals with properties that explain psychiatric disease symptoms, including fictive perception, altered sense of self, and unpredictable behavior. To distinguish dysfunction at the behavioral versus network level, we monitored the interactive behavior of a humanoid robot driven by the network. Mild perturbations in network connectivity resulted in the spontaneous appearance of uncompensated prediction errors and altered interactions within the network without external changes in behavior, correlating to the fictive sensations and agency experienced by episodic disease patients. In contrast, more severe deficits resulted in unstable network dynamics resulting in overt changes in behavior similar to those observed in chronic disease patients. These findings demonstrate that prediction error disequilibrium may represent an intrinsic property of schizophrenic brain networks reporting the severity and variability of disease symptoms. Moreover, these results support a systems-level model for psychiatric disease that features the spontaneous generation of maladaptive signals in hierarchical neural networks.

  3. Spontaneous Large Serous Retinal Pigment Epithelial Tear

    Directory of Open Access Journals (Sweden)

    Voraporn Chaikitmongkol

    2012-10-01

    Full Text Available Purpose: To report cases of spontaneous retinal pigment epithelial (RPE tear complicating serous pigment epithelial detachment (PED. Methods: The records of 3 Asian patients with spontaneous giant RPE tear were reviewed retrospectively by including clinical presentation, angiography, optical coherence tomography, fundus autofluorescence imaging, and visual outcome. Results: Three patients (4 eyes were included in this study, with a mean age of 48.3 (42–56 years, and a mean follow-up period of 7.75 (4–18 months. Fundus examination in all patients showed giant RPE tear associated with bullous PED. Two cases had a history of prior corticosteroid use, and 1 had no history of medication use. All 3 patients developed spontaneous resolution of subretinal fluid with no treatment. However, in patients who used corticosteroids, initial progression of the tear and subretinal fluid were observed despite ceasing medication. On subsequent follow-up, an incomplete RPE regeneration was demonstrated by fundus autofluorescence imaging, and choroidal neovascularization developed in 1 patient. Conclusion: Large PED with RPE tear is a rare manifestation. When the fovea is spared, visual prognosis is favorable. No specific treatment is required, but careful choroidal neovascularization monitoring should be performed.

  4. Hemodynamic Effect of Laser Therapy in Spontaneously Hypertensive Rats

    Directory of Open Access Journals (Sweden)

    Suely Tomimura

    2014-08-01

    Full Text Available Systemic arterial hypertension (SAH is considered to be the greatest risk factor for the development of neuro-cardiovascular pathologies, thus constituting a severe Public Health issue in the world. The Low-Level Laser Therapy (LLLT, or laser therapy, activates components of the cellular structure, therefore converting luminous energy into photochemical energy and leading to biophysical and biochemical reactions in the mitochondrial respiratory chain. The LLLT promotes cellular and tissue photobiomodulation by means of changes in metabolism, leading to molecular, cellular and systemic changes. The objective of this study was to analyze the action of low-level laser in the hemodynamic modulation of spontaneously hypertensive rats, in the long term. Animals (n = 16 were randomly divided into the Laser Group (n = 8, which received three weekly LLLT irradiations for seven weeks, and into the Sham Group (n = 8, which received three weekly simulations of laser for seven weeks, accounting for 21 applications in each group. After seven weeks, animals were cannulated by the implantation of a catheter in the left carotid artery. On the following day, the systemic arterial pressure was recorded. The Laser Group showed reduced levels of mean blood pressure, with statistically significant reduction (169 ± 4 mmHg* vs. 182 ± 4 mmHg from the Sham Group and reduced levels of diastolic pressure (143 ± 4 mmHg* vs. 157 ± 3 mmHg from the Sham Group, revealing a 13 and 14 mmHg decrease, respectively. Besides, there was a concomitant important decline in heart rate (312 ± 14 bpm vs. 361 ± 13 bpm from the Sham Group. Therefore, laser therapy was able to produce hemodynamic changes, thus reducing pressure levels in spontaneously hypertensive rats.

  5. Hemodynamic Effect of Laser Therapy in Spontaneously Hypertensive Rats

    Energy Technology Data Exchange (ETDEWEB)

    Tomimura, Suely, E-mail: suelytomimura@uol.com.br [Programa de Pós-Graduação em Biofotônica em Ciências da Saúde da Universidade Nove de Julho (UNINOVE) (Brazil); Silva, Bianca Passos Assumpção [Programa de Graduação e Pós-Graduação em Medicina da UNINOVE (Brazil); Sanches, Iris Callado [Laboratório de Fisiologia Translacional da UNINOVE (Brazil); Canal, Marina [Programa de Graduação e Pós-Graduação em Medicina da UNINOVE (Brazil); Consolim-Colombo, Fernanda [Programa de Graduação e Pós-Graduação em Medicina da UNINOVE (Brazil); Unidade de Hipertensão e Central Médica de Laser do Instituto do Coração - Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo (InCor/HC-FMUSP), São Paulo, SP (Brazil); Conti, Felipe Fernandes; Angelis, Katia De [Laboratório de Fisiologia Translacional da UNINOVE (Brazil); Chavantes, Maria Cristina [Programa de Pós-Graduação em Biofotônica em Ciências da Saúde da Universidade Nove de Julho (UNINOVE) (Brazil); Programa de Graduação e Pós-Graduação em Medicina da UNINOVE (Brazil); Unidade de Hipertensão e Central Médica de Laser do Instituto do Coração - Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo (InCor/HC-FMUSP), São Paulo, SP (Brazil)

    2014-08-15

    Systemic arterial hypertension (SAH) is considered to be the greatest risk factor for the development of neuro-cardiovascular pathologies, thus constituting a severe Public Health issue in the world. The Low-Level Laser Therapy (LLLT), or laser therapy, activates components of the cellular structure, therefore converting luminous energy into photochemical energy and leading to biophysical and biochemical reactions in the mitochondrial respiratory chain. The LLLT promotes cellular and tissue photobiomodulation by means of changes in metabolism, leading to molecular, cellular and systemic changes. The objective of this study was to analyze the action of low-level laser in the hemodynamic modulation of spontaneously hypertensive rats, in the long term. Animals (n = 16) were randomly divided into the Laser Group (n = 8), which received three weekly LLLT irradiations for seven weeks, and into the Sham Group (n = 8), which received three weekly simulations of laser for seven weeks, accounting for 21 applications in each group. After seven weeks, animals were cannulated by the implantation of a catheter in the left carotid artery. On the following day, the systemic arterial pressure was recorded. The Laser Group showed reduced levels of mean blood pressure, with statistically significant reduction (169 ± 4 mmHg* vs. 182 ± 4 mmHg from the Sham Group) and reduced levels of diastolic pressure (143 ± 4 mmHg* vs. 157 ± 3 mmHg from the Sham Group), revealing a 13 and 14 mmHg decrease, respectively. Besides, there was a concomitant important decline in heart rate (312 ± 14 bpm vs. 361 ± 13 bpm from the Sham Group). Therefore, laser therapy was able to produce hemodynamic changes, thus reducing pressure levels in spontaneously hypertensive rats.

  6. Impact of Released Fual Moisture on Atmospheric Dynamics

    Science.gov (United States)

    Brian E. Potter

    2003-01-01

    A common component of fire incident reports and prescribed burn preparations is an estimate of the energy that was or will be released by the fire. Typically, this is based on the energy released by combustion of the fuel load, reduced to account for the energy that is required to evaporate moisture in the fuel materials. (e.g., Byram 1959, Anderson 1968, Simard et al...

  7. Nuclear energy: fusion and fission - From the atomic nucleus to energy

    International Nuclear Information System (INIS)

    2002-09-01

    Matter is made up of atoms. In 1912, the English physicist Ernest Rutherford (who had shown that the atom had a nucleus), and the Danish physicist Niels Bohr developed a model in which the atom was made up of a positively charged nucleus surrounded by a cloud of electrons. In 1913, Rutherford discovered the proton, and in 1932, the English physicist Chadwick discovered the neutron. In 1938, Hahn and Strassmann discovered spontaneous fission and the French physicist Frederic Joliot-Curie, assisted by Lew Kowarski and Hans Von Halban, showed in 1939 that splitting uranium nuclei caused an intense release of heat. The discovery of the chain reaction would enable the exploitation of nuclear energy. 'It was the Second World War leaders who, by encouraging research for military purposes, contributed to the development of nuclear energy'. During the Second World War, from 1939 to 1945, studies of fission continued in the United States, with the participation of emigre physicists. The Manhattan project was launched, the aim of which was to provide the country with a nuclear weapon (used at Hiroshima and Nagasaki in 1945). After the war ended, research into energy production by the nuclear fission reaction continued for civil purposes. CEA (the French Atomic Energy Commission) was set up in France in 1945 under the impetus of General de Gaulle. This public research body is responsible for giving France mastery of the atom in the research, health, energy, industrial, safety and defense sectors. (authors)

  8. Peptide secreted by human alveolar macrophages releases neutrophil granule contents

    International Nuclear Information System (INIS)

    MacArthur, C.K.; Miller, E.J.; Cohen, A.B.

    1987-01-01

    A monoclonal antibody was developed against an 8000-kDa enzyme-releasing peptide (ERP) released from human alveolar macrophages. ERP was isolated on an immunoaffinity column containing the antibody bound to staphylococcal protein A-Sepharose, and by autoradiography. Release of ERP from the macrophages is not changed by plastic adherence, phagocytosis, calcium ionophore, or phorbol esters. The peptide was not antigenically similar to interferon-γ, tumor necrosis factor, or interleukin lα or 1β. The release of constituents from azurophilic and specific granules was the main identified biologic function of ERP. ERP was a more effective secretagogue in the untreated neutrophils and f-met-leu-phe was more effective in the cytochalasin B-treated neutrophils. Absorption of ERP from macrophage-conditioned medium removed a small amount of the chemotactic activity; however, the immunopurified peptide was not chemotactic or chemokinetic for neutrophils, and at high concentrations, it suppressed base line chemokinesis. Treatment of washed macrophages with trypsin released active ERP of approximately the same m.w. of spontaneously secreted ERP. These studies showed that human alveolar macrophages release a peptide which is a secretagogue for human neutrophils under conditions which may be encountered in the lungs during certain disease states. Proteolytic enzymes which are free in the lungs may release the peptide and lead to the secretion of neutrophil enzymes

  9. Putative role of border cells in generating spontaneous morphological activity within Kölliker's organ.

    Science.gov (United States)

    Dayaratne, M W Nishani; Vlajkovic, Srdjan M; Lipski, Janusz; Thorne, Peter R

    2015-12-01

    Kölliker's organ is a transient epithelial structure, comprising a major part of the organ of Corti during pre-hearing stages of development. The auditory system is spontaneously active during development, which serves to retain and refine neural connections. Kölliker's organ is considered a key candidate for generating such spontaneous activity, most likely through purinergic (P2 receptor) signalling and inner hair cell (IHC) activation. Associated with the spontaneous neural activity, ATP released locally by epithelial cells induces rhythmic morphological changes within Kölliker's organ, the purpose of which is not understood. These changes are accompanied by a shift in cellular refractive index, allowing optical detection of this activity in real-time. Using this principle, we investigated the origin of spontaneous morphological activity within Kölliker's organ. Apical turns of Wistar rat cochleae (P9-11) were dissected, and the purinergic involvement was studied following acute tissue exposure to a P2 receptor agonist (ATPγS) and antagonist (suramin). ATPγS induced a sustained darkening throughout Kölliker's organ, reversed by suramin. This effect was most pronounced in the region closest to the inner hair cells, which also displayed the highest frequency of intrinsic morphological events. Additionally, suramin alone induced swelling of this region, suggesting a tight regulation of cell volume by ATP-mediated mechanisms. Histological analysis of cochlear tissues demonstrates the most profound volume changes in the border cell region immediately adjacent to the IHCs. Together, these results underline the role of purinergic signalling in initiating morphological events within Kölliker's organ, and suggest a key involvement of border cells surrounding IHCs in regulating this spontaneous activity. Copyright © 2015. Published by Elsevier B.V.

  10. Spontaneous Coronary Artery Dissection Associated With Pregnancy.

    Science.gov (United States)

    Tweet, Marysia S; Hayes, Sharonne N; Codsi, Elisabeth; Gulati, Rajiv; Rose, Carl H; Best, Patricia J M

    2017-07-25

    Spontaneous coronary artery dissection (SCAD) is the most common cause of pregnancy-associated myocardial infarction and remains poorly characterized. This study sought to assess presentation, clinical factors, and outcomes of pregnancy-associated spontaneous coronary artery dissection (P-SCAD) compared with spontaneous coronary artery dissection not associated with pregnancy (NP-SCAD). A Mayo Clinic registry was established in 2010 to include comprehensive retrospective and prospective SCAD data. Records were reviewed to identify women who were pregnant or ≤12 weeks postpartum at time of SCAD. Complete records were available for 323 women; 54 women met criteria for P-SCAD (4 during pregnancy) and they were compared with 269 women with NP-SCAD. Most events occurred within the first month postpartum (35 of 50). Compared with NP-SCAD, P-SCAD patients more frequently presented with ST-segment elevation myocardial infarction (57% vs. 36%; p = 0.009), left main or multivessel SCAD (24% vs. 5%; p vs. 14%; p = 0.0027, respectively), and left ventricular function ≤35% (26% vs. 10%; p = 0.0071). Among women with imaging of other vascular territories, P-SCAD was less likely with a diagnosis of fibromuscular dysplasia and extracoronary vascular abnormalities (42% vs. 64%; p = 0.047; and 46% vs. 77%; p = 0.0032, respectively). Compared with U.S. birth data, women with P-SCAD were more often multiparous (p = 0.0167), had a history of infertility therapies (p = 0.0004), and had pre-eclampsia (p = 0.001). On long-term follow-up (median 2.3 years) recurrent SCAD occurred in 51 patients, with no difference in the Kaplan Meier 5-year recurrence rates (10% vs. 23%; p = 0.18). P-SCAD patients had more acute presentations and high-risk features than women with NP-SCAD did. The highest frequency of P-SCAD occurred during the first postpartum month and P-SCAD patients less often had extracoronary vascular abnormalities. Hormonal, hemodynamic variations, and yet

  11. Why do cells release vesicles?

    NARCIS (Netherlands)

    Nieuwland, Rienk; Sturk, Augueste

    2010-01-01

    Prokaryotic and eukaryotic cells release vesicles into their environment. To answer the question why eukaryotic cells release vesicles, we may learn from prokaryotes. Bacteria release outer membrane vesicles, resembling microparticles, which act as "multi-purpose carriers". They contain signalling

  12. Effects of Combining Feed Grade Urea and a Slow-release Urea Product on Characteristics of Digestion, Microbial Protein Synthesis and Digestible Energy in Steers Fed Diets with Different Starch:ADF Ratios.

    Science.gov (United States)

    López-Soto, M A; Rivera-Méndez, C R; Aguilar-Hernández, J A; Barreras, A; Calderón-Cortés, J F; Plascencia, A; Dávila-Ramos, H; Estrada-Angulo, A; Valdes-García, Y S

    2014-02-01

    As a result of the cost of grains, the replacement of grains by co-products (i.e. DDGS) in feedlot diets is a common practice. This change produces diets that contain a lower amount of starch and greater amount of fibre. Hypothetically, combining feed grade urea (U) with slow release urea (Optigen) in this type of diet should elicit a better synchrony between starch (high-rate of digestion) and fibre (low-rate of digestion) promoting a better microbial protein synthesis and ruminal digestion with increasing the digestible energy of the diet. Four cannulated Holstein steers (213±4 kg) were used in a 4×4 Latin square design to examine the combination of Optigen and U in a finishing diet containing different starch:acid detergent fibre ratios (S:F) on the characteristics of digestive function. Three S:F ratios (3.0, 4.5, and 6.0) were tested using a combination of U (0.80%) and Optigen (1.0%). Additionally, a treatment of 4.5 S:F ratio with urea (0.80% in ration) as the sole source of non-protein nitrogen was used to compare the effect of urea combination at same S:F ratio. The S:F ratio of the diet was manipulated by replacing the corn grain by dried distillers grain with solubles and roughage. Urea combination did not affect ruminal pH. The S:F ratio did not affect ruminal pH at 0 and 2 h post-feeding but, at 4 and 6 h, the ruminal pH decreased as the S:F ratio increased (linear, p<0.05). Ruminal digestion of OM, starch and feed N were not affected by urea combination or S:F ratio. The urea combination did not affect ADF ruminal digestion. ADF ruminal digestion decreased linearly (p = 0.02) as the S:F ratio increased. Compared to the urea treatment (p<0.05) and within the urea combination treatment (quadratic, p<0.01), the flow of microbial nitrogen (MN) to the small intestine and ruminal microbial efficiency were greater for the urea combination at a S:F ratio of 4.5. Irrespective of the S:F ratio, the urea combination improved (2.8%, p = 0.02) postruminal N

  13. Effect of in vitro inorganic lead on dopamine release from superfused rat striatal synaptosomes

    International Nuclear Information System (INIS)

    Minnema, D.J.; Greenland, R.D.; Michaelson, I.A.

    1986-01-01

    The effect of inorganic lead in vitro in several aspects of [ 3 H]dopamine release from superfused rat striatal synaptosomes was examined. Under conditions of spontaneous release, lead (1-30 microM) induced dopamine release in a concentration-dependent manner. The onset of the lead-induced release was delayed by approximately 15-30 sec. The magnitude of dopamine release induced by lead was increased when calcium was removed from the superfusing buffer. Lead-induced release was unaffected in the presence of putative calcium, sodium, and/or potassium channel blockers (nickel, tetrodotoxin, tetraethylammonium, respectively). Depolarization-evoked dopamine release, produced by a 1-sec exposure to 61 mM potassium, was diminished at calcium concentrations below 0.254 mM. The onset of depolarization-evoked release was essentially immediate following exposure of the synaptosomes to high potassium. The combination of lead (3 or 10 microM) with high potassium reduced the magnitude of depolarization-evoked dopamine release. This depression of depolarization-evoked release by lead was greater in the presence of 0.25 mM than 2.54 mM calcium in the superfusing buffer. These findings demonstrate multiple actions of lead on synaptosomal dopamine release. Lead can induce dopamine release by yet unidentified neuronal mechanisms independent of external calcium. Lead can also reduce depolarization-evoked dopamine release by apparent competition with calcium influx at the neuronal membrane calcium channel

  14. Intraocular and extraocular hemorrhage associated with ligature release of non-valved glaucoma drainage implant

    Directory of Open Access Journals (Sweden)

    Michelle Go

    2017-04-01

    Conclusions and importance: This is the first report of a rare occurrence of intraocular and extraocular hemorrhage associated following spontaneous release of ligature of a non-valved glaucoma drainage implant. The presumed mechanism was sudden shallowing of the anterior chamber resulting in the tube irritating uveal vasculature. We do not have an explanation for the extraocular blood.

  15. Understanding dynamic friction through spontaneously evolving laboratory earthquakes.

    Science.gov (United States)

    Rubino, V; Rosakis, A J; Lapusta, N

    2017-06-29

    Friction plays a key role in how ruptures unzip faults in the Earth's crust and release waves that cause destructive shaking. Yet dynamic friction evolution is one of the biggest uncertainties in earthquake science. Here we report on novel measurements of evolving local friction during spontaneously developing mini-earthquakes in the laboratory, enabled by our ultrahigh speed full-field imaging technique. The technique captures the evolution of displacements, velocities and stresses of dynamic ruptures, whose rupture speed range from sub-Rayleigh to supershear. The observed friction has complex evolution, featuring initial velocity strengthening followed by substantial velocity weakening. Our measurements are consistent with rate-and-state friction formulations supplemented with flash heating but not with widely used slip-weakening friction laws. This study develops a new approach for measuring local evolution of dynamic friction and has important implications for understanding earthquake hazard since laws governing frictional resistance of faults are vital ingredients in physically-based predictive models of the earthquake source.

  16. RAVEN Beta Release

    International Nuclear Information System (INIS)

    Rabiti, Cristian; Alfonsi, Andrea; Cogliati, Joshua Joseph; Mandelli, Diego; Kinoshita, Robert Arthur; Wang, Congjian; Maljovec, Daniel Patrick; Talbot, Paul William

    2016-01-01

    This documents the release of the Risk Analysis Virtual Environment (RAVEN) code. A description of the RAVEN code is provided, and discussion of the release process for the M2LW-16IN0704045 milestone. The RAVEN code is a generic software framework to perform parametric and probabilistic analysis based on the response of complex system codes. RAVEN is capable of investigating the system response as well as the input space using Monte Carlo, Grid, or Latin Hyper Cube sampling schemes, but its strength is focused toward system feature discovery, such as limit surfaces, separating regions of the input space leading to system failure, using dynamic supervised learning techniques. RAVEN has now increased in maturity enough for the Beta 1.0 release.

  17. RAVEN Beta Release

    Energy Technology Data Exchange (ETDEWEB)

    Rabiti, Cristian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Alfonsi, Andrea [Idaho National Lab. (INL), Idaho Falls, ID (United States); Cogliati, Joshua Joseph [Idaho National Lab. (INL), Idaho Falls, ID (United States); Mandelli, Diego [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kinoshita, Robert Arthur [Idaho National Lab. (INL), Idaho Falls, ID (United States); Wang, Congjian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Maljovec, Daniel Patrick [Idaho National Lab. (INL), Idaho Falls, ID (United States); Talbot, Paul William [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-02-01

    This documents the release of the Risk Analysis Virtual Environment (RAVEN) code. A description of the RAVEN code is provided, and discussion of the release process for the M2LW-16IN0704045 milestone. The RAVEN code is a generic software framework to perform parametric and probabilistic analysis based on the response of complex system codes. RAVEN is capable of investigating the system response as well as the input space using Monte Carlo, Grid, or Latin Hyper Cube sampling schemes, but its strength is focused toward system feature discovery, such as limit surfaces, separating regions of the input space leading to system failure, using dynamic supervised learning techniques. RAVEN has now increased in maturity enough for the Beta 1.0 release.

  18. Quantitative proteome of medulla oblongata in spontaneously hypertensive rats.

    Science.gov (United States)

    Sun, Dongmei; Cheng, Yu; Zhou, Danfeng; Liu, Tanshu; Chen, Shaoqin; Liang, Jing; Tang, Chunzhi; Lai, Xinsheng

    2013-01-04

    We performed an extensive quantitative proteomic analysis on the pooled medulla sample of the 11-week-old spontaneously hypertensive rats (SHR) compared to age-matched normotensive Wistar rats, using iTRAQ technology coupled with nano two-dimentional liquid chromatography followed by high resolution mass spectrometric abundance indexes techniques. Many differentially expressed proteins identified were involved in energy metabolism, such as mitochondrial part, pyruvate dehydrogenase complex, and respiratory chain. These proteins were included in citrate cycle (TCA cycle), pyruvate metabolism and oxidative phosphorylation. The proteomic analysis and subsequent Western blotting on two independent cohorts of animials indicated that the dysregulation of energy metabolism existed in the medulla of the SHR rats. The differentially expressed proteins in the dysregulation of energy metabolism in the medulla of SHR rats included down-regulated ATP6V1D, ATP6VOA1, ATP5L, DLD proteins and up-regulated AK1 protein. MAO-A protein also exhibited decreased regulation, as well as the other 3 above-mentioned energy-relative proteins (ATP6V1D, ATP5L and DLD proteins) belonging to the heterocycle metabolic process. A receiver operating characteristic curve (ROC) analysis on 4 of the differentially expressed proteins respectively resulted in an area under the receiver operating characteristic curve (AUC) of 0.95, 0.90, 0.92, and 0.81 for differentiating the SHR rats from the normotensive rats. This dysfunction in energy metabolism localizes to the medulla, the lower part of brain stem, and is, therefore, likely to contribute to the development, as well as to pathophysiological complications of hypertension.

  19. Multiple genetic switches spontaneously modulating bacterial mutability

    Directory of Open Access Journals (Sweden)

    Johnston Randal N

    2010-09-01

    Full Text Available Abstract Background All life forms need both high genetic stability to survive as species and a degree of mutability to evolve for adaptation, but little is known about how the organisms balance the two seemingly conflicting aspects of life: genetic stability and mutability. The DNA mismatch repair (MMR system is essential for maintaining genetic stability and defects in MMR lead to high mutability. Evolution is driven by genetic novelty, such as point mutation and lateral gene transfer, both of which require genetic mutability. However, normally a functional MMR system would strongly inhibit such genomic changes. Our previous work indicated that MMR gene allele conversion between functional and non-functional states through copy number changes of small tandem repeats could occur spontaneously via slipped-strand mis-pairing during DNA replication and therefore may play a role of genetic switches to modulate the bacterial mutability at the population level. The open question was: when the conversion from functional to defective MMR is prohibited, will bacteria still be able to evolve by accepting laterally transferred DNA or accumulating mutations? Results To prohibit allele conversion, we "locked" the MMR genes through nucleotide replacements. We then scored changes in bacterial mutability and found that Salmonella strains with MMR locked at the functional state had significantly decreased mutability. To determine the generalizability of this kind of mutability 'switching' among a wider range of bacteria, we examined the distribution of tandem repeats within MMR genes in over 100 bacterial species and found that multiple genetic switches might exist in these bacteria and may spontaneously modulate bacterial mutability during evolution. Conclusions MMR allele conversion through repeats-mediated slipped-strand mis-pairing may function as a spontaneous mechanism to switch between high genetic stability and mutability during bacterial evolution.

  20. Being Spontaneous: The Future of Telehealth Implementation?

    Science.gov (United States)

    Mars, Maurice; Scott, Richard E

    2017-09-01

    The smartphone simplifies interprofessional communication, and smartphone applications can facilitate telemedicine activity. Much has been written about the steps that need to be followed to implement and establish a successful telemedicine service that is integrated into everyday clinical practice. A traditional and systematic approach has evolved incorporating activities such as strategy development, needs assessment, business cases and plans, readiness assessment, implementation plans, change management interventions, and ongoing monitoring and evaluation. This "best practice" has been promoted in the telehealth literature for many years. In contrast, several recent initiatives have arisen without any such formal undertakings. This article describes the strengths and weaknesses of two "spontaneous" telemedicine services in dermatology and burn management that have evolved in South Africa. Two spontaneous services were identified and reviewed. In one unsolicited service, doctors at rural referring hospitals have been taking photographs of skin lesions and sending them with a brief text message history to dermatologists using the instant messaging smartphone app, WhatsApp. In the other, burns service, admissions to the burns unit or the clinic were triaged by telephonic description of the case and completion of a preadmission questionnaire. More recently, management and referral decisions are made only after completion of the questionnaire and subsequent submission of photographs of the burn sent by WhatsApp, with the decision transmitted by text message. Although efficient and effective, potential legal and ethical shortcomings have been identified. These "spontaneous" telehealth services challenge traditional best practice, yet appear to lead to truly integrated practice and, therefore, are successful and warrant further study.